# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	27	1.39812e-35	6.814022622222223e-33	2.96892	180	0.01614784	115	2.356395861130435e-11	1.751823	91	118	0.01100895	
GO Biological Process	viral gene expression	28	1.493874e-34	7.020674273571429e-32	2.823293	189	0.01695523	145	1.8849986169655173e-9	1.663451	93	127	0.01125091	
GO Biological Process	viral transcription	36	1.036526e-30	3.788790453888889e-28	2.772777	172	0.01543016	162	1.5560582482716048e-8	1.668516	83	113	0.01004113	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	44	5.935082e-29	1.7749941826818182e-26	3.008107	142	0.01273885	182	1.0344405583516484e-7	1.703696	69	92	0.008347447	
GO Biological Process	multi-organism metabolic process	45	8.872245e-29	2.594441599e-26	2.390434	210	0.01883915	126	4.394959788888889e-10	1.638021	106	147	0.01282361	
GO Biological Process	rRNA metabolic process	49	1.621358e-27	4.354173453469388e-25	2.000445	298	0.02673365	224	0.0000013990496061607144	1.38576	158	259	0.01911444	
GO Biological Process	rRNA processing	50	2.007774e-27	5.2840596132e-25	2.016598	291	0.02610568	226	0.00000175965641539823	1.388197	154	252	0.01863053	
GO Biological Process	cotranslational protein targeting to membrane	56	9.883976e-27	2.3225578604285713e-24	2.837097	143	0.01282856	227	0.000001994074281585903	1.622567	70	98	0.008468425	
GO Biological Process	nuclear-transcribed mRNA catabolic process	59	8.488367e-26	1.893193582254237e-23	2.079725	253	0.02269669	183	1.0400463729508197e-7	1.479978	129	198	0.0156061	
GO Biological Process	protein targeting to ER	61	1.605335e-25	3.4630497155737706e-23	2.730483	145	0.01300798	225	0.0000014710691734666667	1.619354	72	101	0.00871038	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	65	2.057323e-24	4.1649712856923074e-22	2.558348	155	0.01390509	194	2.3033717089690724e-7	1.644202	76	105	0.00919429	
GO Biological Process	protein localization to endoplasmic reticulum	71	2.701227e-23	5.006400858169014e-21	2.360042	172	0.01543016	209	6.115732137177034e-7	1.575461	86	124	0.01040406	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	84	1.488681e-19	2.3320896760714286e-17	2.182597	168	0.01507132	434	0.001273713883294931	1.427285	71	113	0.008589402	
GO Biological Process	translational initiation	88	2.675972e-19	4.0014904031818186e-17	2.119984	177	0.01587871	269	0.000015046895803345723	1.477331	93	143	0.01125091	
GO Biological Process	regulation of DNA-templated transcription in response to stress	112	2.768141e-17	3.2523185195535716e-15	2.021387	176	0.015789	440	0.0014495209720227272	1.412588	74	119	0.008952335	
GO Biological Process	mitotic DNA damage checkpoint	114	9.479172e-17	1.0941791609473684e-14	2.056059	163	0.01462277	482	0.0027113573483402487	1.431105	63	100	0.007621582	
GO Biological Process	protein targeting to membrane	120	1.848459e-16	2.02698933175e-14	2.010667	169	0.01516103	272	0.000016127675237867648	1.491793	88	134	0.01064602	
GO Biological Process	DNA-templated transcription, elongation	147	3.236604e-14	2.8973110228571427e-12	2.100047	129	0.01157262	675	0.01989280145925926	1.342306	65	110	0.007863537	
GO Biological Process	ribonucleoprotein complex export from nucleus	159	6.670369e-14	5.520464507610063e-12	2.004612	141	0.01264914	541	0.0055262813687615535	1.362957	75	125	0.009073312	
GO Biological Process	mitochondrial translational elongation	160	6.856349e-14	5.6389185306875e-12	2.364592	97	0.008701893	481	0.002598388998066528	1.469855	55	85	0.006653762	
GO Cellular Component	ribosomal subunit	26	2.050317e-31	1.3626722215384617e-29	2.381615	232	0.02081277	33	1.0360412509090909e-8	1.522582	124	185	0.01500121	
GO Cellular Component	large ribosomal subunit	35	2.30015e-22	1.1356169142857143e-20	2.501894	147	0.0131874	44	0.000001001852770909091	1.58024	80	115	0.0096782	
GO Cellular Component	mitochondrial ribosome	47	1.282836e-15	4.7164693787234046e-14	2.606744	92	0.008253342	122	0.015031234622950819	1.389681	52	85	0.00629083	
GO Cellular Component	cytosolic ribosome	50	5.285012e-15	1.8265001472e-13	2.012996	152	0.01363596	45	0.0000013511808	1.582003	78	112	0.009436245	
GO Cellular Component	mitochondrial large ribosomal subunit	53	1.033603e-14	3.369935818867924e-13	3.098599	65	0.005831165	120	0.01317470256	1.514396	34	51	0.004113235	
GO Cellular Component	methyltransferase complex	59	9.978839e-14	2.9226158969491527e-12	2.046399	132	0.01184175	134	0.029656052059701496	1.347979	54	91	0.006532785	
GO Cellular Component	MLL1 complex	70	1.618897e-11	3.99636288e-10	3.063718	50	0.004485512	113	0.007637862456637167	1.723279	22	29	0.002661505	
GO Cellular Component	small ribosomal subunit	71	2.058537e-11	5.010073149295774e-10	2.224745	88	0.007894501	114	0.008021151663157896	1.451296	46	72	0.005564965	
GO Cellular Component	cytosolic large ribosomal subunit	80	3.33045e-10	7.193772000000001e-9	2.176778	81	0.007266529	75	0.00018362541312	1.638527	44	61	0.00532301	
GO Cellular Component	cytosolic small ribosomal subunit	95	4.644481e-9	8.448066492631579e-8	2.306563	62	0.005562035	142	0.03402024338028169	1.497187	29	44	0.003508347	
GO Cellular Component	AP-type membrane coat adaptor complex	102	1.673846e-8	2.8356920470588233e-7	2.071959	73	0.006548847	123	0.016340726634146343	1.530857	31	46	0.003750302	
GO Cellular Component	axon cytoplasm	119	2.607483e-7	0.0000037863282554621846	2.025305	64	0.005741455	135	0.0295981184	1.533326	27	40	0.003266392	
GO Cellular Component	clathrin adaptor complex	139	0.000001816955	0.000022587757122302155	2.051325	53	0.004754643	106	0.004616865509433962	1.741556	23	30	0.002782482	
GO Molecular Function	structural constituent of ribosome	7	1.306766e-28	7.88166578857143e-26	2.371628	212	0.01901857	26	1.3115112002307693e-8	1.570485	112	162	0.01354948	
GO Molecular Function	rRNA binding	9	6.846685e-20	3.2118560077777777e-17	3.485391	77	0.006907688	103	0.03446910073592233	1.476536	39	60	0.004718122	
GO Molecular Function	ribonucleoprotein complex binding	10	6.559423e-19	2.7693883906000003e-16	2.20715	158	0.01417422	83	0.0048372466262650606	1.402463	71	115	0.008589402	
Human Phenotype	Hamartomatous polyposis	92	0.000001140302	0.00008270907876086957	3.429211	22	0.001973625	135	0.030616163923703702	2.271594	9	9	0.001088797	
Mouse Phenotype Single KO	thin interventricular septum	48	7.014673e-9	0.0000013381950137708334	2.572069	49	0.004395802	389	0.04942699077634962	1.793364	15	19	0.001814662	
Mouse Phenotype Single KO	abnormal adipose tissue development	229	0.00004808886	0.0019229244149344977	2.240203	31	0.002781017	368	0.04475782347826087	2.065086	10	11	0.001209775	
Mouse Phenotype Single KO	decreased fatty acid oxidation	244	0.00006398218	0.002401167304344262	2.502773	24	0.002153046	385	0.049283354550649354	1.703696	18	24	0.002177595	
Mouse Phenotype Single KO	increased cellular sensitivity to hydrogen peroxide	403	0.0006095424	0.013850073838213397	2.0656	26	0.002332466	389	0.04942699077634962	1.793364	15	19	0.001814662	
Mouse Phenotype	enlarged liver sinusoidal spaces	3	1.305169e-18	4.159573603e-15	2.552591	116	0.01040639	398	0.01176101973165829	1.606738	29	41	0.003508347	
Mouse Phenotype	decreased spongiotrophoblast size	94	5.145784e-8	0.000005233919236595745	2.649939	41	0.00367812	555	0.03617186428108109	1.793364	15	19	0.001814662	
Mouse Phenotype	hemorrhagic ascites	143	8.088348e-7	0.00005407880785174825	2.720377	32	0.002870728	525	0.0327572608	2.065086	10	11	0.001209775	
Mouse Phenotype	ketoaciduria	292	0.00003208551	0.0010505806887328767	2.756049	22	0.001973625	525	0.0327572608	2.065086	10	11	0.001209775	
Mouse Phenotype	increased kidney tumor incidence	341	0.00006308657	0.0017688290198533722	2.356582	27	0.002422176	600	0.043172807045000004	1.845671	13	16	0.001572707