# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	actin polymerization or depolymerization	8	1.912775e-138	3.146275778125e-135	8.795211	241	0.03328729	358	0.009334685841340782	1.853457	25	43	0.004244482	
GO Biological Process	chondrocyte development	27	3.742746e-72	1.8241035042222222e-69	4.686945	210	0.02900552	391	0.014153207883887468	2.173599	15	22	0.002546689	
GO Biological Process	positive regulation of cell-substrate adhesion	37	1.366465e-57	4.8598143067567564e-55	2.903993	304	0.04198895	485	0.03247920659175258	1.4599	49	107	0.008319185	
GO Biological Process	positive regulation of cell morphogenesis involved in differentiation	38	3.043873e-57	1.054061179131579e-54	2.545716	376	0.0519337	444	0.023696116669819817	1.41945	61	137	0.01035654	
GO Biological Process	regulation of protein localization to nucleus	52	2.578256e-52	6.524475135384615e-50	2.377382	390	0.0538674	487	0.03345523083983573	1.312684	91	221	0.01544992	
GO Biological Process	chondrocyte differentiation	61	2.83057e-46	6.106142726229508e-44	2.785097	260	0.0359116	258	0.0019072506688759688	1.799647	35	62	0.005942275	
GO Biological Process	nephron development	70	8.83218e-44	1.660323666e-41	2.241005	367	0.05069061	467	0.027818171084368307	1.437189	55	122	0.009337861	
GO Biological Process	regulation of dendrite development	80	1.424369e-40	2.342908958875e-38	2.212589	349	0.04820442	511	0.0401068809001957	1.400764	58	132	0.009847199	
GO Biological Process	embryonic skeletal system development	82	1.1356e-39	1.822361024390244e-37	2.244109	331	0.04571823	318	0.005435535990566037	1.515581	58	122	0.009847199	
GO Biological Process	cartilage development	83	1.175328e-39	1.863390500240964e-37	2.158093	360	0.04972376	492	0.03490991763821138	1.381443	65	150	0.01103565	
GO Biological Process	embryonic placenta development	105	1.58795e-34	1.9900794333333332e-32	2.649348	209	0.0288674	367	0.009971685823160763	1.576063	44	89	0.007470289	
GO Biological Process	regulation of cell-substrate adhesion	110	1.293258e-33	1.5470892747272727e-31	2.003125	362	0.05	541	0.04827647924399261	1.326875	77	185	0.01307301	
GO Biological Process	placenta development	125	1.049905e-31	1.1052559916000002e-29	2.289324	252	0.03480663	469	0.02784682608763326	1.397456	64	146	0.01086587	
GO Biological Process	endosome organization	250	2.33297e-17	1.2279820891999999e-15	2.787185	92	0.01270718	436	0.022254926354816514	1.593973	36	72	0.006112054	
GO Biological Process	negative regulation of embryonic development	290	8.730818e-15	3.961683933172414e-13	2.547224	90	0.01243094	297	0.003575742920909091	2.207039	18	26	0.003056027	
GO Biological Process	regulation of myotube differentiation	325	2.299629e-13	9.31102092646154e-12	2.486361	84	0.01160221	537	0.04793355661080075	1.622954	28	55	0.00475382	
GO Biological Process	negative regulation of Notch signaling pathway	339	8.319189e-13	3.2292686740707964e-11	2.942259	60	0.008287293	514	0.04171515645136187	1.835484	19	33	0.003225806	
GO Biological Process	modulation by virus of host morphology or physiology	405	8.711743e-11	2.830563608320987e-9	2.636366	59	0.008149171	233	0.0007922841880257511	2.125297	24	36	0.004074703	
GO Biological Process	embryonic skeletal joint development	445	8.467106e-10	2.5037898394157302e-8	2.600017	54	0.007458564	473	0.02838118097040169	2.337827	11	15	0.001867572	
GO Biological Process	modification by symbiont of host morphology or physiology	459	1.565939e-9	4.489366296514161e-8	2.37467	62	0.008563536	408	0.01810751613063726	1.763544	26	47	0.004414261	
GO Molecular Function	histone deacetylase binding	18	5.538491e-19	1.2990838334444443e-16	2.130389	171	0.02361878	42	0.0017635113057142856	1.623491	55	108	0.009337861	
Mouse Phenotype Single KO	small kidney	48	1.515675e-34	2.891465828125e-32	2.026112	362	0.05	186	0.024036140376344085	1.376217	79	183	0.01341256	
Mouse Phenotype Single KO	abnormal osteoblast differentiation	146	1.540047e-16	9.659048204794521e-15	2.50696	105	0.01450276	204	0.02941084311911765	1.771081	25	45	0.004244482	
Mouse Phenotype	dilated esophagus	8	4.324463e-100	5.168273842875e-97	8.098665	184	0.02541436	360	0.022082019204166668	2.608319	9	11	0.001528014	
Mouse Phenotype	kinked tail	28	2.777124e-64	9.48288663e-62	2.828336	354	0.04889503	393	0.026085132763358776	1.4282	56	125	0.00950764	
Mouse Phenotype	abnormal fibroblast physiology	32	1.353251e-60	4.0432602534375e-58	2.446389	428	0.05911602	193	0.0026047057069430056	1.373463	109	253	0.01850594	
Mouse Phenotype	increased cell proliferation	33	3.223702e-60	9.339943885454546e-58	2.355833	457	0.06312155	130	0.0005399523267692307	1.421132	111	249	0.0188455	
Mouse Phenotype	abnormal basisphenoid bone morphology	57	1.198942e-41	2.0110674494736843e-39	2.697857	246	0.0339779	474	0.0398666872721519	1.593973	30	60	0.005093379	
Mouse Phenotype	abnormal incisor morphology	76	8.283949e-34	1.0421425840657894e-31	2.224924	286	0.03950276	240	0.005683699783749999	1.549282	52	107	0.008828523	
Mouse Phenotype	decreased epididymal fat pad weight	100	4.903258e-29	4.6880049737999994e-27	3.193389	130	0.0179558	348	0.019485485592241378	1.645391	32	62	0.005432937	
Mouse Phenotype	abnormal zygomatic arch morphology	108	8.933428e-27	7.9085652877777785e-25	3.93433	91	0.01256906	483	0.043364756788819875	2.125297	12	18	0.002037351	
Mouse Phenotype	epidermal hyperplasia	176	5.802641e-19	3.152218784147727e-17	2.180779	162	0.02237569	405	0.028260026081481482	1.4599	49	107	0.008319185	
Mouse Phenotype	decreased bone ossification	209	7.631776e-17	3.4912636524401913e-15	2.437476	113	0.01560773	455	0.03761814324395604	1.700238	24	45	0.004074703	
Mouse Phenotype	abnormal epidermis stratum basale morphology	252	4.44006e-14	1.684579907142857e-12	2.229823	111	0.01533149	329	0.016704720558966567	1.675022	31	59	0.005263158	
Mouse Phenotype	intestine polyps	280	6.242169e-13	2.131477778892857e-11	2.59114	75	0.01035912	441	0.03532635570068027	1.835484	19	33	0.003225806	
Mouse Phenotype	increased B cell derived lymphoma incidence	299	4.294816e-12	1.3733356446822744e-10	2.143278	102	0.0140884	479	0.042522677242171195	1.512231	37	78	0.006281834	
Mouse Phenotype	gastrointestinal tract polyps	361	5.12731e-10	1.3579559808864266e-8	2.202752	77	0.01063536	406	0.028437710896551723	1.809375	21	37	0.003565365	
Mouse Phenotype	abnormal Paneth cell morphology	395	3.421867e-9	8.282650730886077e-8	2.129874	75	0.01035912	468	0.038965549057692304	1.761759	21	38	0.003565365	
Mouse Phenotype	tumor regression	442	4.622209e-8	9.998402771266967e-7	6.188171	15	0.002071823	450	0.036773050773333336	2.789452	7	8	0.001188455