# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	14	5.139299e-22	4.830573967214286e-19	3.434886	87	0.02371865	257	0.017991261292607003	1.703369	38	113	0.01025088	
GO Biological Process	regulation of DNA-templated transcription in response to stress	18	2.98538e-19	2.1824786344444443e-16	3.071484	88	0.02399128	279	0.025044090887813616	1.66005	39	119	0.01052064	
GO Biological Process	liver regeneration	20	1.132641e-18	7.452211459499999e-16	4.753818	50	0.01363141	271	0.021602144588929888	2.315557	16	35	0.004316159	
GO Biological Process	ncRNA processing	21	3.050414e-18	1.9114475155238095e-15	2.110766	165	0.04498364	140	0.0012867894722142857	1.445396	113	396	0.03048287	
GO Biological Process	rRNA processing	29	4.006654e-15	1.8180537926206897e-12	2.316582	110	0.02998909	175	0.0035506854505714287	1.527625	76	252	0.02050175	
GO Biological Process	macromolecular complex disassembly	31	6.437513e-15	2.7326204376451613e-12	2.375805	103	0.0280807	26	1.660709325923077e-7	1.988985	75	191	0.02023199	
GO Biological Process	cellular protein complex disassembly	32	9.375637e-15	3.85543772759375e-12	2.818744	75	0.02044711	34	3.080623688735294e-7	2.211036	55	126	0.0148368	
GO Biological Process	rRNA metabolic process	34	1.294866e-14	5.0115122629411765e-12	2.264447	111	0.03026172	191	0.004940500390157068	1.505895	77	259	0.02077151	
GO Biological Process	translational elongation	39	7.58167e-14	2.558133218717949e-11	3.077056	61	0.01663032	51	0.0000015441018298823529	2.216061	49	112	0.01321824	
GO Biological Process	protein targeting to ER	40	1.599013e-13	5.26035301675e-11	3.204706	56	0.01526718	182	0.004087634396648352	1.855598	37	101	0.009981117	
GO Biological Process	mitochondrial translational termination	41	4.128434e-13	1.3250259269756098e-10	3.497947	48	0.01308615	59	0.000006000316651525424	2.328865	40	87	0.0107904	
GO Biological Process	protein complex disassembly	42	4.523926e-13	1.4173891008095236e-10	2.415598	86	0.02344602	41	6.343501358780488e-7	2.038856	64	159	0.01726463	
GO Biological Process	regulation of cellular amino acid metabolic process	43	5.051669e-13	1.5459281946744184e-10	4.123837	39	0.0106325	243	0.012987933	2.026113	24	60	0.006474238	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	45	5.431102e-13	1.5881749159555557e-10	3.144172	55	0.01499455	245	0.013827165680816328	1.883246	29	78	0.007823037	
GO Biological Process	mitochondrial translation	47	6.593451e-13	1.846025993808511e-10	3.089889	56	0.01526718	76	0.000017879548847368418	2.130259	45	107	0.0121392	
GO Biological Process	cotranslational protein targeting to membrane	48	7.796015e-13	2.1372450288541665e-10	3.195529	53	0.01444929	160	0.0021741472511875	1.912402	37	98	0.009981117	
GO Biological Process	protein localization to endoplasmic reticulum	50	1.016666e-12	2.6756615788e-10	2.752098	66	0.01799346	217	0.008969089503225806	1.71566	42	124	0.01132992	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	52	1.429326e-12	3.6170193911538463e-10	2.926517	59	0.01608506	125	0.000508201948536	1.927497	43	113	0.01159968	
GO Biological Process	mRNA catabolic process	53	1.579618e-12	3.9219232569811323e-10	2.2138	98	0.02671756	208	0.006954759251923077	1.545743	65	213	0.01753439	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	55	2.841563e-12	6.798568639454545e-10	2.907251	58	0.01581243	320	0.03720120029625	1.631192	38	118	0.01025088	
GO Cellular Component	ribosomal subunit	30	1.248374e-14	7.19063424e-13	2.620544	84	0.02290076	27	0.0000031398304	1.861833	68	185	0.01834367	
GO Cellular Component	ribosome	31	2.449343e-14	1.3653111948387097e-12	2.302182	105	0.02862595	24	0.00000131170968	1.781434	83	236	0.02239007	
GO Cellular Component	mitochondrial ribosome	39	1.528132e-11	6.770800246153846e-10	3.530394	41	0.01117775	37	0.00007226570724324325	2.145296	36	85	0.009711357	
GO Cellular Component	large ribosomal subunit	43	1.429698e-9	5.7453910325581397e-8	2.637852	51	0.01390403	41	0.0003429166688780488	1.893975	43	115	0.01159968	
GO Cellular Component	nuclear nucleosome	44	1.526457e-9	5.994812945454545e-8	5.600707	20	0.005452563	66	0.021964943127272728	2.152745	17	40	0.004585919	
GO Cellular Component	methyltransferase complex	46	4.251447e-9	1.5970653078260868e-7	2.497014	53	0.01444929	44	0.00039842653090909095	2.003848	36	91	0.009711357	
GO Cellular Component	mitochondrial large ribosomal subunit	50	7.949071e-8	0.0000027471989376	3.621768	25	0.006815703	47	0.0012870059438297872	2.284343	23	51	0.006204478	
GO Cellular Component	proteasome complex	59	4.820161e-7	0.000014117352894915254	2.639863	35	0.009541985	65	0.02147879808	1.862236	25	68	0.006743998	
GO Cellular Component	endopeptidase complex	60	4.881462e-7	0.00001405861056	2.638372	35	0.009541985	74	0.024109990054054054	1.835247	25	69	0.006743998	
GO Cellular Component	Bcl-2 family protein complex	64	8.080857e-7	0.0000218183139	6.30773	12	0.003271538	58	0.010227799613793104	4.34167	6	7	0.001618559	
GO Cellular Component	small ribosomal subunit	66	8.742544e-7	0.000022889569745454544	2.612193	34	0.009269357	70	0.021626201417142856	1.82913	26	72	0.007013758	
GO Cellular Component	nucleosome	76	0.000001796694	0.000040851147789473685	2.567609	33	0.008996728	80	0.0318467376	1.640187	34	105	0.009171837	
GO Cellular Component	histone methyltransferase complex	77	0.000002397978	0.00005381436342857143	2.267073	41	0.01117775	51	0.005277335717647059	1.982067	27	69	0.007283518	
GO Cellular Component	DNA packaging complex	93	0.00002071199	0.0003848421367741935	2.211009	35	0.009541985	76	0.02872006484210526	1.628126	36	112	0.009711357	
GO Cellular Component	proteasome accessory complex	104	0.0000916341	0.0015225358153846155	3.434332	14	0.003816794	68	0.0218310336	2.532641	12	24	0.003237119	
GO Cellular Component	transcription factor TFIIIC complex	172	0.001542552	0.015497266604651163	6.120602	5	0.001363141	81	0.032009621333333335	4.221068	5	6	0.0013488	
GO Cellular Component	Sin3-type complex	174	0.001904738	0.01891601875862069	2.615305	13	0.003544166	78	0.029514417230769235	2.849221	9	16	0.002427839	
GO Molecular Function	structural constituent of ribosome	6	2.811361e-15	1.9782610236666663e-12	2.75375	81	0.02208288	9	0.000015893512591111113	1.938565	62	162	0.01672511	
GO Molecular Function	unfolded protein binding	22	2.152192e-9	4.130252101818182e-7	2.69718	48	0.01308615	16	0.0033979078199999997	1.911427	40	106	0.0107904	
GO Molecular Function	NF-kappaB binding	48	0.000001404145	0.00012350625395833335	3.380188	22	0.005997819	28	0.010677177140714285	2.713544	15	28	0.004046399	
GO Molecular Function	SNAP receptor activity	97	0.0001568565	0.006827300443298969	2.305298	25	0.006815703	37	0.0420400401027027	2.223782	18	41	0.004855678	
GO Molecular Function	ligase activity, forming carbon-sulfur bonds	113	0.0002490938	0.00930684976637168	2.193874	26	0.007088332	27	0.010860962085185185	2.406009	19	40	0.005125438	
Mouse Phenotype Single KO	abnormal adrenal chromaffin cell morphology	56	1.796197e-7	0.000029371028444642858	4.165273	20	0.005452563	49	0.039753956859183676	3.683841	8	11	0.002158079	
Mouse Phenotype Single KO	abnormal neuroendocrine cell morphology	125	0.00002058503	0.00150797695768	2.691587	24	0.006543075	34	0.017800502372352943	3.277535	11	17	0.002967359	
Mouse Phenotype	abnormal neuroendocrine cell morphology	176	0.00009510817	0.00516664325778409	2.336916	26	0.007088332	59	0.030316569772881358	2.743694	13	24	0.003506879