# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	protein targeting to ER	27	4.774877e-15	2.327133571962963e-12	2.312637	111	0.01101737	459	0.008675545219389978	1.405971	61	101	0.007562608	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	30	1.968563e-14	8.634773505666667e-12	2.367223	101	0.01002481	483	0.010828731810144928	1.416995	56	92	0.006942723	
GO Biological Process	cotranslational protein targeting to membrane	32	7.285066e-14	2.9957557341875e-11	2.282887	104	0.01032258	486	0.011491077796707818	1.401503	59	98	0.007314654	
GO Biological Process	viral transcription	33	1.530896e-13	6.104563776969697e-11	2.122494	119	0.01181141	701	0.04302962965192582	1.318468	64	113	0.00793454	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	41	1.649086e-12	5.292761627804877e-10	2.080385	114	0.01131514	654	0.033837624030581034	1.321785	67	118	0.008306472	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	48	6.980328e-12	1.9136278365e-9	2.045309	112	0.01111663	532	0.015735220539473682	1.374581	62	105	0.007686586	
GO Biological Process	posttranscriptional gene silencing by RNA	78	8.730604e-10	1.472897667128205e-7	2.141019	80	0.007940447	434	0.005668651605760369	1.597592	35	51	0.004339202	
GO Biological Process	posttranscriptional gene silencing	82	1.52722e-9	2.450815607317073e-7	2.113599	80	0.007940447	469	0.009434952496375265	1.566869	35	52	0.004339202	
GO Biological Process	gene silencing by miRNA	105	1.475763e-8	0.000001849482411142857	2.141928	68	0.00674938	437	0.006205462200228833	1.640125	31	44	0.003843293	
GO Biological Process	mitochondrial DNA replication	106	1.488285e-8	0.0000018475794636792453	5.145956	19	0.001885856	720	0.04925715260416667	2.32792	7	7	0.0008678403	
GO Biological Process	mitochondrial genome maintenance	109	2.327519e-8	0.00000280989197440367	2.730641	41	0.004069479	489	0.011630265957259713	1.884506	17	21	0.002107612	
GO Biological Process	positive regulation of cytoplasmic translation	110	2.825412e-8	0.000003379963318909091	6.432296	15	0.001488834	720	0.04925715260416667	2.32792	7	7	0.0008678403	
GO Biological Process	protein targeting to mitochondrion	117	3.928541e-8	0.0000044184334204273514	2.015119	74	0.007344913	385	0.002717361185168831	1.608381	38	55	0.004711133	
GO Biological Process	production of small RNA involved in gene silencing by RNA	169	5.620889e-7	0.000043766436894082836	2.136998	53	0.005260546	432	0.005537590484027777	1.784738	23	30	0.002851475	
GO Biological Process	negative regulation of Notch signaling pathway	175	6.877706e-7	0.00005171641900228571	2.04386	58	0.005756824	662	0.03437222237160121	1.622489	23	33	0.002851475	
GO Biological Process	production of miRNAs involved in gene silencing by miRNA	180	9.416639e-7	0.00006884086255611112	2.2347	46	0.004565757	445	0.007306905863370787	1.810604	21	27	0.002603521	
GO Biological Process	heart valve formation	267	0.00001146496	0.0005650464743071161	2.122778	41	0.004069479	713	0.04862569785694249	1.969778	11	13	0.001363749	
GO Biological Process	error-free translesion synthesis	513	0.0003697871	0.009485435572904483	2.138344	26	0.002580645	455	0.007952770347912088	1.960353	16	19	0.001983635	
GO Molecular Function	protein phosphatase activator activity	81	0.0002230603	0.011626673908641975	2.399513	22	0.002183623	102	0.047897596588235294	2.32792	8	8	0.0009918175	
Human Phenotype	Basal cell carcinoma	15	3.479175e-8	0.000015477689849999998	2.728765	40	0.003970223	81	0.018501946998765433	1.904662	18	22	0.002231589	
Mouse Phenotype Single KO	abnormal prechordal plate morphology	6	1.800884e-7	0.0002748449131333333	4.599073	18	0.0017866	462	0.022935430870129874	2.32792	8	8	0.0009918175	
Mouse Phenotype Single KO	abnormal thymus involution	54	0.00004554896	0.007723922717037037	2.246826	31	0.003076923	575	0.041958297662608696	1.969778	11	13	0.001363749	
Mouse Phenotype Single KO	fusion of atlas and occipital bones	88	0.0001896386	0.019733189320454543	2.488981	21	0.002084367	600	0.0465258013	2.095128	9	10	0.001115795	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	44	0.00001421354	0.0030885376349999998	2.173134	38	0.003771712	582	0.012018211498453607	1.707141	22	30	0.002727498	
Mouse Phenotype	abnormal prechordal plate morphology	73	0.00008322798	0.010900585161369863	2.407219	25	0.00248139	742	0.03394938435040431	1.969778	11	13	0.001363749	
Mouse Phenotype	abnormal platelet ATP level	121	0.0003485944	0.027544719490909093	2.320395	22	0.002183623	812	0.046708452206896546	1.862336	12	15	0.001487726	
Mouse Phenotype	abnormal adrenal chromaffin cell morphology	125	0.000390453	0.029864969064	2.007336	30	0.002977667	812	0.046708452206896546	1.862336	12	15	0.001487726