# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	negative regulation of gene expression, epigenetic	5	8.914356e-35	2.34608021208e-31	4.164054	112	0.02254882	251	0.0036754088342231075	1.703902	45	114	0.01034483	
GO Biological Process	regulation of gene expression, epigenetic	9	9.397231e-31	1.3739795858777778e-27	2.563167	195	0.03925911	182	0.00026198455546153846	1.549085	89	248	0.02045977	
GO Biological Process	ncRNA processing	13	3.350499e-29	3.3914781800769226e-26	2.248373	238	0.04791625	66	4.5372092434848485e-9	1.635057	150	396	0.03448276	
GO Biological Process	RNA catabolic process	14	4.463163e-29	4.1950544226428575e-26	2.586411	181	0.03644051	56	9.489112338035713e-10	1.862744	104	241	0.02390805	
GO Biological Process	mRNA catabolic process	20	2.297411e-26	1.51158156745e-23	2.635752	158	0.03180995	72	1.1889317332222224e-8	1.864426	92	213	0.02114943	
GO Biological Process	chromatin silencing	21	7.843636e-25	4.914971720190477e-22	4.286069	76	0.01530099	345	0.02470565633652174	1.64652	37	97	0.008505747	
GO Biological Process	viral gene expression	22	8.657956e-25	5.178638318363637e-22	3.385941	101	0.02033421	150	0.00003341500837933333	1.869373	55	127	0.01264368	
GO Biological Process	viral transcription	29	9.124142e-23	4.140158088896552e-20	3.364599	93	0.01872358	155	0.0000490449089	1.909979	50	113	0.01149425	
GO Biological Process	nuclear-transcribed mRNA catabolic process	30	9.556341e-23	4.1917297073e-20	2.58272	140	0.02818603	85	7.658336744705883e-8	1.853065	85	198	0.01954023	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	32	2.42151e-22	9.957703153125e-20	3.368458	91	0.01832092	139	0.000014023934443165467	1.93879	53	118	0.01218391	
GO Biological Process	rRNA processing	35	8.38294e-22	3.1517459274285713e-19	2.39503	154	0.03100463	106	7.899021207830189e-7	1.695788	99	252	0.02275862	
GO Biological Process	rRNA metabolic process	36	1.074975e-21	3.929332229166667e-19	2.365233	157	0.03160862	108	8.651173762314815e-7	1.683289	101	259	0.02321839	
GO Biological Process	translation	42	4.160517e-21	1.3035296000714286e-18	2.008093	219	0.044091	81	5.906383034074074e-8	1.612905	139	372	0.03195402	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	44	4.931421e-21	1.47483111225e-18	2.973914	102	0.02053553	332	0.021731775379216868	1.604382	42	113	0.009655172	
GO Biological Process	regulation of DNA-templated transcription in response to stress	45	3.964478e-20	1.159301466711111e-17	2.783713	108	0.02174351	279	0.01068661255949821	1.632309	45	119	0.01034483	
GO Biological Process	nucleosome organization	46	5.917803e-20	1.692877601673913e-17	2.490124	130	0.02617274	159	0.00006985746468742139	1.716523	68	171	0.01563218	
GO Biological Process	protein folding	47	7.658985e-20	2.1443528428723404e-17	2.243453	159	0.03201127	129	0.000007123430835271318	1.680781	88	226	0.02022989	
GO Biological Process	chromatin assembly or disassembly	48	8.461806e-20	2.3197688573750003e-17	2.430045	135	0.02717938	168	0.00016364493236309524	1.67327	69	178	0.01586207	
GO Biological Process	gene silencing	49	1.199373e-19	3.22092843e-17	2.52056	125	0.0251661	309	0.015810210589644012	1.486812	62	180	0.01425287	
GO Biological Process	multi-organism metabolic process	53	2.085339e-19	5.177542622830189e-17	2.733412	107	0.02154218	162	0.00010756134108641975	1.761858	60	147	0.0137931	
GO Cellular Component	nucleosome	22	1.158305e-24	9.097959272727273e-23	4.309346	75	0.01509966	42	0.000012116736	1.973281	48	105	0.01103448	
GO Cellular Component	DNA packaging complex	23	1.368809e-23	1.0283921530434784e-21	3.825352	82	0.01650896	40	0.0000063982958399999995	1.965573	51	112	0.01172414	
GO Cellular Component	ribosomal subunit	27	1.63495e-21	1.046368e-19	2.741539	119	0.02395812	44	0.0000190033776	1.703288	73	185	0.01678161	
GO Cellular Component	ficolin-1-rich granule lumen	28	3.908116e-19	2.4118658742857144e-17	2.821623	100	0.02013288	79	0.007064606460759493	1.601301	46	124	0.01057471	
GO Cellular Component	ribosome	36	6.45529e-17	3.0985392000000002e-15	2.218227	137	0.02758204	43	0.000012795695330232557	1.627852	89	236	0.02045977	
GO Cellular Component	small ribosomal subunit	39	2.150049e-14	9.526370953846153e-13	3.290709	58	0.01167707	61	0.0015157712891803279	1.918467	32	72	0.007356322	
GO Cellular Component	nuclear chromosome, telomeric region	42	1.014506e-13	4.173967542857143e-12	2.555745	82	0.01650896	67	0.002575931663283582	1.635057	50	132	0.01149425	
GO Cellular Component	protein-DNA complex	45	8.928659e-13	3.428605056e-11	2.030152	123	0.02476344	45	0.0000953640576	1.624049	76	202	0.01747126	
GO Cellular Component	chromosome, telomeric region	46	6.428856e-12	2.415013732173913e-10	2.224358	92	0.01852225	93	0.026407611870967743	1.447466	56	167	0.01287356	
GO Cellular Component	cytosolic ribosome	49	1.614783e-11	5.694581681632653e-10	2.347958	79	0.01590497	55	0.001326217693090909	1.734329	45	112	0.01034483	
GO Cellular Component	mitotic spindle	50	2.265214e-11	7.828579584e-10	2.392083	75	0.01509966	59	0.0014711204989830506	1.865177	35	81	0.008045977	
GO Cellular Component	methyltransferase complex	57	2.92377e-10	8.863639578947368e-9	2.36586	68	0.01369036	94	0.029280371744680855	1.612778	34	91	0.007816092	
GO Cellular Component	melanosome	64	1.257938e-9	3.3964326000000004e-8	2.026647	89	0.01791826	66	0.0022114286836363638	1.726621	42	105	0.009655172	
GO Cellular Component	large ribosomal subunit	67	1.663293e-9	4.2898064238805976e-8	2.368138	62	0.01248238	95	0.029562387536842104	1.538945	41	115	0.009425287	
GO Cellular Component	mitochondrial ribosome	70	3.521704e-9	8.693577874285714e-8	2.797867	44	0.008858466	97	0.033254522721649485	1.625055	32	85	0.007356322	
GO Cellular Component	cytosolic small ribosomal subunit	71	4.94656e-9	1.2038951661971831e-7	3.089152	37	0.007449164	87	0.018320692965517242	1.962069	20	44	0.004597701	
GO Cellular Component	small-subunit processome	97	3.421114e-7	0.000006094520610309279	3.251024	26	0.005234548	77	0.005684453485714286	2.219941	18	35	0.004137931	
GO Cellular Component	NuA4 histone acetyltransferase complex	102	5.378885e-7	0.000009112464	3.468615	23	0.004630562	103	0.04994440077669903	2.398084	10	18	0.002298851	
GO Cellular Component	preribosome	105	7.275321e-7	0.000011973099702857143	2.277409	45	0.009059795	64	0.00195850818	1.874292	33	76	0.007586207	
GO Cellular Component	aggresome	133	0.00002899654	0.00037673700090225563	2.098667	38	0.007650493	91	0.025102428131868134	1.992255	18	39	0.004137931	
GO Molecular Function	unfolded protein binding	7	6.910339e-24	4.167921608285714e-21	3.651628	88	0.01771693	31	0.000019790420709677418	1.995387	49	106	0.01126437	
GO Molecular Function	ribonucleoprotein complex binding	10	9.772299e-20	4.1258646378e-17	2.978257	95	0.01912623	59	0.006411049752542372	1.689085	45	115	0.01034483	
GO Molecular Function	structural constituent of ribosome	11	2.504459e-16	9.612568998181819e-14	2.535689	101	0.02033421	37	0.00011497133594594594	1.73195	65	162	0.01494253	
GO Molecular Function	nucleosome binding	12	4.522532e-15	1.5911775086666668e-12	3.053476	68	0.01369036	72	0.02328232455	1.831264	28	66	0.006436782	
GO Molecular Function	protein binding involved in protein folding	13	3.400448e-13	1.1043608812307691e-10	4.758168	34	0.006845178	68	0.017172686976470588	2.398084	15	27	0.003448276	
GO Molecular Function	translation initiation factor binding	131	0.0001462449	0.004713327998473283	2.130173	30	0.006039863	75	0.029719496770666667	2.227898	16	31	0.003678161	
Mouse Phenotype Single KO	abnormal embryonic erythropoiesis	29	1.221018e-9	3.8554695951724135e-7	2.944431	43	0.008657137	46	0.03843025685217392	2.381546	16	29	0.003678161	
Mouse Phenotype Single KO	abnormal embryonic hematopoiesis	47	1.149974e-7	0.000022404918974468084	2.0207	68	0.01369036	14	0.000004532183239928571	2.60622	32	53	0.007356322	
Mouse Phenotype	abnormal embryonic erythropoiesis	37	2.304397e-9	5.95468641e-7	2.762988	46	0.009261123	46	0.00633361170326087	2.506385	18	31	0.004137931	
Mouse Phenotype	decreased cellular sensitivity to ultraviolet irradiation	48	9.507543e-9	0.0000018937837213125	4.772382	21	0.004227904	55	0.009377286254181818	3.165471	11	15	0.002528736	
Mouse Phenotype	abnormal embryonic erythrocyte morphology	59	6.696984e-8	0.000010852519326101695	2.432694	47	0.009462452	96	0.041967521490625	2.102935	19	39	0.004367816	
Mouse Phenotype	increased fibroblast apoptosis	74	2.781729e-7	0.00003594069049864865	2.477835	41	0.00825448	101	0.04271961769603961	1.97842	22	48	0.005057471	
Mouse Phenotype	increased incidence of tumors by UV-induction	107	0.000001725516	0.00015418372407476638	5.353705	13	0.002617274	107	0.048171802850467293	2.988382	9	13	0.002068966