# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of gene expression, epigenetic	23	1.823855e-103	1.0434829541304346e-100	2.119379	1023	0.03246176	772	0.04587771146243523	1.096612	208	248	0.01448367	
GO Biological Process	endoplasmic reticulum unfolded protein response	101	2.992462e-46	3.898792817623762e-44	2.13801	442	0.01402551	431	0.0011376282185150814	1.192807	104	114	0.007241836	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	104	1.520061e-45	1.9233156441346152e-43	2.095481	456	0.01446976	747	0.03887119275769746	1.145508	99	113	0.00689367	
GO Biological Process	regulation of DNA-templated transcription in response to stress	105	2.466214e-45	3.090753335809524e-43	2.019053	497	0.01577077	642	0.018677687829906545	1.153676	105	119	0.007311469	
GO Biological Process	cotranslational protein targeting to membrane	202	2.454095e-27	1.5986849556930694e-25	2.028105	289	0.009170527	533	0.005203495712007505	1.187423	89	98	0.00619734	
GO Biological Process	cytoplasmic translation	385	1.5384e-16	5.2581313246753244e-15	2.285786	127	0.004029955	501	0.003631818336327345	1.277093	42	43	0.002924587	
GO Biological Process	somatic recombination of immunoglobulin gene segments	832	8.153075e-9	1.2894989654447116e-7	2.005075	83	0.00263375	778	0.046225909439588694	1.307499	22	22	0.001531927	
GO Cellular Component	histone methyltransferase complex	64	1.091608e-28	2.9473415999999998e-27	2.007992	312	0.009900362	131	0.017000960977099234	1.193804	63	69	0.004386881	
GO Cellular Component	PcG protein complex	72	5.013447e-26	1.20322728e-24	2.049987	267	0.008472425	109	0.0077977728	1.250652	44	46	0.003063853	
GO Cellular Component	sex chromosome	97	8.541305e-17	1.5215850556701029e-15	2.349675	122	0.003871295	121	0.01333413627768595	1.307499	26	26	0.001810459	
GO Cellular Component	nuclear ubiquitin ligase complex	121	1.305427e-13	1.864279219834711e-12	2.095408	124	0.003934759	102	0.004905343058823529	1.274812	39	40	0.002715688	
GO Cellular Component	COPI-coated vesicle	124	1.813444e-13	2.5271219612903224e-12	2.339708	96	0.003046265	145	0.02490115928275862	1.307499	23	23	0.00160156	
GO Molecular Function	unfolded protein binding	11	5.315518e-34	2.040192454181818e-31	2.125582	325	0.01031288	81	0.0025735373007407403	1.196485	97	106	0.006754404	
Human Phenotype	Abnormality of cells of the monocyte/macrophage lineage	32	2.756972e-13	5.749148173749999e-11	2.43906	87	0.002760678	164	0.03799126883292683	1.307499	26	26	0.001810459	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	26	7.772007e-37	2.737241080730769e-34	2.366839	280	0.00888494	264	0.0195299351375	1.220333	56	60	0.00389945	
Mouse Phenotype	abnormal cellular replicative senescence	49	1.64143e-37	3.202798414285714e-35	2.089896	375	0.01189947	205	0.0007868012742439025	1.229672	79	84	0.00550101	
Mouse Phenotype	early cellular replicative senescence	55	2.027381e-35	3.5243254074545456e-33	2.12899	338	0.01072539	291	0.005394625043298969	1.217945	68	73	0.004735046