# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of gene expression, epigenetic	52	2.566912e-299	6.495768270769231e-297	2.454723	2189	0.03759812	589	0.011173577229202038	1.119082	207	248	0.01478044	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	145	1.42584e-142	1.2939743834482758e-140	2.718741	870	0.01494306	689	0.022984953261248185	1.162762	98	113	0.006997501	
GO Biological Process	cytoskeleton-dependent intracellular transport	148	1.641883e-140	1.459833675472973e-138	2.115216	1411	0.02423524	309	0.00008679876553074432	1.205762	134	149	0.009568011	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	149	2.13944e-139	1.8894557691275168e-137	2.484896	999	0.01715876	345	0.0002659103971449275	1.222086	103	113	0.007354516	
GO Biological Process	transport along microtubule	155	3.897983e-137	3.3092618256129034e-135	2.206903	1251	0.02148709	367	0.00044012014495912804	1.204567	115	128	0.008211353	
GO Biological Process	organelle transport along microtubule	162	3.482141e-133	2.8284872480864194e-131	2.671651	837	0.01437626	421	0.0014195550995961994	1.259479	62	66	0.00442699	
GO Biological Process	regulation of DNA-templated transcription in response to stress	183	5.898331e-125	4.2413189961202185e-123	2.297902	1045	0.01794885	308	0.0000854884261525974	1.228069	109	119	0.007782935	
GO Biological Process	chromatin assembly or disassembly	193	7.866222e-122	5.363296129430052e-120	2.042428	1330	0.02284399	616	0.013806202771266233	1.137365	151	178	0.01078186	
GO Biological Process	multi-organism metabolic process	228	2.42965e-100	1.40227036622807e-98	2.137985	981	0.01684959	204	0.0000012298472355392157	1.240408	136	147	0.009710818	
GO Biological Process	regulation of megakaryocyte differentiation	230	1.09659e-99	6.273925134782609e-98	2.43196	742	0.01274454	679	0.02012243659646539	1.199605	68	76	0.004855409	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to hypoxia	247	4.221651e-93	2.24909738902834e-91	2.452677	681	0.01169681	431	0.0018094834040371232	1.237602	72	78	0.005141021	
GO Biological Process	ribonucleoprotein complex export from nucleus	264	3.381509e-86	1.6855029140530304e-84	2.183052	802	0.0137751	435	0.0018775645382298853	1.190573	111	125	0.007925741	
GO Biological Process	ribonucleoprotein complex localization	287	8.89529e-80	4.078505962020906e-78	2.108481	803	0.01379227	475	0.003217885238105263	1.182381	112	127	0.007997144	
GO Biological Process	ncRNA transcription	289	2.193844e-79	9.989201797923876e-78	2.292848	663	0.01138764	226	0.000004588359889159292	1.282443	88	92	0.00628347	
GO Biological Process	snRNA metabolic process	303	1.455499e-75	6.321092851815181e-74	2.402875	573	0.00984181	361	0.0003654013719944598	1.247196	80	86	0.005712246	
GO Biological Process	viral gene expression	310	6.040216e-74	2.56397426916129e-72	2.113571	739	0.01269301	264	0.00001814056873560606	1.235166	117	127	0.008354159	
GO Biological Process	positive regulation of actin filament polymerization	317	1.060801e-72	4.403495381388012e-71	2.071542	762	0.01308806	609	0.013099953038916257	1.212172	66	73	0.004712603	
GO Biological Process	RNA 3'-end processing	319	1.53933e-72	6.349856887147335e-71	2.194313	665	0.011422	446	0.0021980994230493276	1.202903	96	107	0.006854695	
GO Biological Process	histone lysine methylation	325	2.368006e-71	9.587874139692307e-70	2.02876	787	0.01351746	590	0.011155011429322034	1.222435	62	68	0.00442699	
GO Biological Process	snRNA transcription from RNA polymerase II promoter	329	3.965707e-70	1.5861622617933129e-68	2.398001	533	0.009154772	324	0.00011863468020061728	1.283275	67	70	0.004784006	
GO Cellular Component	histone methyltransferase complex	56	2.204039e-127	6.801034628571429e-126	2.713743	779	0.01338005	140	0.0164504736	1.204719	62	69	0.00442699	
GO Cellular Component	methyltransferase complex	57	1.336395e-124	4.051386947368422e-123	2.540788	856	0.0147026	121	0.007377070492561983	1.193402	81	91	0.005783649	
GO Cellular Component	PcG protein complex	68	2.55291e-108	6.487394823529412e-107	2.726262	656	0.01126741	88	0.0004471527927272727	1.311589	45	46	0.003213138	
GO Cellular Component	intrinsic component of mitochondrial membrane	80	8.231396e-83	1.7779815359999998e-81	2.530065	570	0.009790282	156	0.03173105353846154	1.196349	58	65	0.004141378	
GO Cellular Component	integral component of mitochondrial membrane	86	8.404784e-80	1.6887752037209302e-78	2.50301	560	0.009618523	160	0.0373168728	1.194093	57	64	0.004069975	
GO Cellular Component	ficolin-1-rich granule lumen	93	1.119391e-72	2.0799006967741935e-71	2.000389	831	0.0142732	98	0.0013106400391836735	1.189362	110	124	0.007854338	
GO Cellular Component	host cell	106	4.02971e-59	6.569187622641509e-58	2.203803	534	0.009171948	166	0.0471357906506024	1.183002	60	68	0.004284184	
GO Cellular Component	AP-type membrane coat adaptor complex	118	1.274808e-52	1.866837477966102e-51	2.314974	426	0.007316947	106	0.0030549067471698117	1.282443	44	46	0.003141735	
GO Cellular Component	sex chromosome	131	1.822571e-48	2.404124189312977e-47	2.825147	271	0.004654678	169	0.049057807526627216	1.289169	25	26	0.001785077	
GO Cellular Component	euchromatin	155	3.023333e-38	3.370528660645161e-37	2.083207	387	0.006647086	167	0.04748980656287425	1.259479	31	33	0.002213495	
GO Cellular Component	nuclear euchromatin	187	1.754499e-30	1.6212696641711232e-29	2.014551	331	0.005685234	127	0.00886739391496063	1.340735	25	25	0.001785077	
GO Molecular Function	protein transporter activity	67	1.876807e-76	1.1826685304477612e-74	2.08909	786	0.01350028	100	0.008557386032	1.201076	86	96	0.006140664	
GO Molecular Function	histone methyltransferase activity	81	2.123741e-60	1.1069672224691358e-58	2.010327	679	0.01166246	102	0.009537406937254902	1.249838	55	59	0.003927169	
Mouse Phenotype Single KO	abnormal erythropoiesis	28	2.775944e-162	9.078328288571429e-160	2.168685	1539	0.02643376	215	0.014251648146976745	1.182285	97	110	0.006926098	
Mouse Phenotype Single KO	extramedullary hematopoiesis	60	5.823046e-122	8.886938703666667e-120	2.20061	1119	0.01921987	179	0.008437791826815642	1.187845	101	114	0.00721171	
Mouse Phenotype Single KO	abnormal liver sinusoid morphology	111	1.355029e-73	1.1178378876576577e-71	2.167253	694	0.0119201	250	0.0276773951172	1.21885	60	66	0.004284184	
Mouse Phenotype Single KO	enlarged liver sinusoidal spaces	117	9.835158e-72	7.697482205641025e-70	2.508797	500	0.008587967	114	0.0015413359600877192	1.340735	37	37	0.002641914	
Mouse Phenotype Single KO	abnormal circulating tumor necrosis factor level	120	4.187064e-71	3.1950787539999996e-69	2.020789	792	0.01360334	59	0.00009488010029661017	1.251353	98	105	0.006997501	
Mouse Phenotype Single KO	increased circulating tumor necrosis factor level	158	1.117684e-56	6.477615435443038e-55	2.185311	521	0.008948661	167	0.006336073743712574	1.254236	58	62	0.004141378	
Mouse Phenotype Single KO	decreased total retina thickness	211	4.322645e-47	1.8759459841232228e-45	2.316939	379	0.006509679	306	0.041092815545751636	1.27017	36	38	0.002570511	
Mouse Phenotype Single KO	increased circulating interferon-gamma level	246	1.264933e-42	4.708533122357723e-41	2.315752	342	0.005874169	222	0.0164358993	1.278376	41	43	0.002927526	
Mouse Phenotype	abnormal erythropoiesis	37	1.778928e-183	4.59684611027027e-181	2.105764	1860	0.03194724	256	0.004030241607421875	1.169769	130	149	0.009282399	
Mouse Phenotype	abnormal megakaryocyte progenitor cell morphology	64	4.84838e-150	7.243025184374999e-148	2.126614	1488	0.02555779	349	0.015353801694842404	1.166331	107	123	0.007640129	
Mouse Phenotype	abnormal embryonic hematopoiesis	117	2.90093e-95	2.37058048974359e-93	2.11358	956	0.01642019	464	0.042663572250000004	1.20886	55	61	0.003927169	
Mouse Phenotype	enlarged liver sinusoidal spaces	178	2.62993e-68	1.412627007303371e-66	2.325631	552	0.009481115	148	0.00038256177354729725	1.340735	41	41	0.002927526	
Mouse Phenotype	increased circulating interferon-gamma level	239	1.671965e-53	6.688559566945608e-52	2.396337	404	0.006939077	210	0.0018452748211428573	1.289169	50	52	0.003570154	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	248	9.674993e-51	3.7299438739112905e-49	2.820417	285	0.004895141	442	0.03649628380995475	1.296044	29	30	0.002070689	
Mouse Phenotype	interstitial pneumonia	570	9.042899e-25	1.516827321736842e-23	2.116281	235	0.004036344	432	0.034805625374999996	1.340735	22	22	0.001570868