# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	DNA replication-dependent nucleosome assembly	4	1.61879e-25	5.3254144025e-22	25.31593	24	0.01011378	222	0.009116549272522522	2.782838	14	32	0.004742547	
GO Biological Process	ribonucleoprotein complex biogenesis	13	1.087539e-19	1.1008404385384614e-16	2.261158	152	0.06405394	37	2.1109571774864863e-10	1.835377	131	454	0.04437669	
GO Biological Process	chromatin silencing	14	1.678781e-19	1.5779342270714284e-16	5.43	46	0.01938475	160	0.0005519573802625	2.163974	33	97	0.01117886	
GO Biological Process	ncRNA metabolic process	17	2.601104e-18	2.013407502117647e-15	2.154019	156	0.06573957	105	0.000014174949994285715	1.535754	134	555	0.04539295	
GO Biological Process	ribosome biogenesis	19	6.041694e-18	4.184350070842105e-15	2.542433	110	0.04635483	61	6.415599261967213e-8	1.870815	95	323	0.03218157	
GO Biological Process	rRNA processing	21	1.449943e-17	9.085619017619048e-15	2.864635	88	0.03708386	101	0.000008543076859900991	1.842605	73	252	0.024729	
GO Biological Process	chromatin silencing at rDNA	22	1.981757e-17	1.1853609255909092e-14	11.10664	24	0.01011378	266	0.03294581727556391	2.473634	14	36	0.004742547	
GO Biological Process	ncRNA processing	24	2.890493e-17	1.5848332244583333e-14	2.372843	120	0.0505689	107	0.00001782552574766355	1.638381	102	396	0.03455285	
GO Biological Process	negative regulation of gene expression, epigenetic	26	3.396815e-17	1.7191803301923076e-14	4.124494	53	0.0223346	159	0.0005522355596603774	2.064461	37	114	0.01253388	
GO Biological Process	rRNA metabolic process	29	9.194458e-17	4.1720645800689655e-14	2.774939	88	0.03708386	114	0.000025084782383333334	1.792805	73	259	0.024729	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	30	1.70566e-16	7.481593313333333e-14	4.028928	52	0.02191319	148	0.00020492252854729728	2.102289	39	118	0.01321138	
GO Biological Process	cotranslational protein targeting to membrane	31	1.014635e-15	4.306961924193548e-13	4.287028	46	0.01938475	103	0.000012211329702330098	2.401516	37	98	0.01253388	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	32	1.053028e-15	4.3302485787500003e-13	3.910216	51	0.02149178	169	0.0010959297956213017	2.026441	36	113	0.01219512	
GO Biological Process	protein targeting to ER	33	1.51942e-15	6.058802357575757e-13	4.157475	47	0.01980615	118	0.000026149509041525423	2.330184	37	101	0.01253388	
GO Biological Process	nuclear-transcribed mRNA catabolic process	34	2.039936e-15	7.895152301176471e-13	2.896056	75	0.03160556	136	0.00009197304048897058	1.863257	58	198	0.0196477	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	35	2.040961e-15	7.673430228285715e-13	4.378425	44	0.01854193	110	0.00002024607851818182	2.419859	35	92	0.01185637	
GO Biological Process	mRNA catabolic process	36	4.641303e-15	1.6965251715833336e-12	2.758488	79	0.03329119	138	0.00011143928002173913	1.82163	61	213	0.02066396	
GO Biological Process	viral gene expression	38	3.030609e-14	1.0494679955526316e-11	3.578694	51	0.02149178	172	0.0012654360000581397	1.953308	39	127	0.01321138	
GO Biological Process	regulation of hematopoietic stem cell differentiation	40	5.254859e-14	1.728717239525e-11	3.902721	45	0.01896334	198	0.004741311979444445	1.976162	32	103	0.01084011	
GO Biological Process	protein localization to endoplasmic reticulum	41	5.73605e-14	1.840992242682927e-11	3.416076	53	0.0223346	141	0.00011825974634751774	2.103159	41	124	0.01388889	
GO Cellular Component	intracellular ribonucleoprotein complex	15	5.524718e-24	6.364475135999999e-22	2.018851	239	0.1007164	21	5.876370925714286e-11	1.601914	205	814	0.06944444	
GO Cellular Component	ribonucleoprotein complex	17	6.501521e-24	6.608604875294118e-22	2.01628	239	0.1007164	22	8.167384145454545e-11	1.596032	205	817	0.06944444	
GO Cellular Component	nuclear nucleosome	22	7.803183e-18	6.129045556363636e-16	10.82143	25	0.01053519	76	0.015442540294736842	2.38529	15	40	0.005081301	
GO Cellular Component	nucleosome	24	1.391227e-17	1.00168344e-15	5.171481	43	0.01812052	37	0.0000033988265513513516	2.362573	39	105	0.01321138	
GO Cellular Component	DNA packaging complex	26	1.897016e-16	1.2607860184615385e-14	4.491711	46	0.01938475	35	8.290751451428572e-7	2.38529	42	112	0.01422764	
GO Cellular Component	ribosomal subunit	27	4.120902e-16	2.63737728e-14	3.230864	67	0.0282343	47	0.00020741628868085107	1.822275	53	185	0.01795393	
GO Cellular Component	protein-DNA complex	29	2.25126e-14	1.3414404413793103e-12	2.694725	78	0.03286979	27	1.26575744e-8	2.14125	68	202	0.02303523	
GO Cellular Component	ribosome	30	5.873154e-14	3.382936704e-12	2.643483	78	0.03286979	45	0.000089926272	1.751908	65	236	0.02201897	
GO Cellular Component	large ribosomal subunit	38	3.724733e-11	1.693773322105263e-9	3.357848	42	0.01769912	68	0.00755978654117647	1.825265	33	115	0.01117886	
GO Cellular Component	nuclear chromosome, telomeric region	47	5.087124e-10	1.870329845106383e-8	2.935706	45	0.01896334	88	0.03866596363636364	1.638381	34	132	0.01151762	
GO Cellular Component	cytosolic part	48	5.201002e-10	1.87236072e-8	2.176255	78	0.03286979	57	0.002012135343157895	1.616696	61	240	0.02066396	
GO Cellular Component	cytosolic ribosome	50	2.116095e-9	7.31322432e-8	2.799446	45	0.01896334	51	0.00038219361882352944	2.044534	36	112	0.01219512	
GO Cellular Component	U1 snRNP	55	9.489261e-8	0.0000029813532741818182	5.837689	15	0.006321113	40	0.00001603389168	4.352107	13	19	0.004403794	
GO Cellular Component	spliceosomal snRNP complex	56	1.500098e-7	0.000004628873828571428	3.607365	24	0.01011378	58	0.0032573753379310346	2.257048	22	62	0.007452575	
GO Cellular Component	spliceosomal complex	57	2.557138e-7	0.00000775216572631579	2.084778	59	0.02486304	41	0.000023225938419512194	1.915071	56	186	0.01897019	
GO Cellular Component	cytosolic large ribosomal subunit	58	2.769776e-7	0.000008252022289655173	3.282182	26	0.0109566	65	0.006718578313846154	2.189774	21	61	0.007113821	
GO Cellular Component	small nuclear ribonucleoprotein complex	61	0.000001076272	0.000030488492065573773	3.129703	25	0.01053519	64	0.0061136856	2.120257	23	69	0.007791328	
GO Cellular Component	cytosolic small ribosomal subunit	64	0.000008941803	0.00024142868099999998	3.320378	19	0.008006743	89	0.04054320970786517	2.168445	15	44	0.005081301	
GO Cellular Component	proteasome complex	65	0.00001096278	0.00029144128984615384	2.798054	24	0.01011378	82	0.02714142204878049	1.964356	21	68	0.007113821	
GO Cellular Component	endopeptidase complex	66	0.00001106212	0.0002896264145454545	2.796474	24	0.01011378	86	0.03177528781395349	1.935887	21	69	0.007113821	
GO Molecular Function	structural constituent of ribosome	6	1.040941e-15	7.324754836666666e-13	3.310637	63	0.02654867	11	0.00014838414747272727	2.002465	51	162	0.01727642	
GO Molecular Function	exonuclease activity	9	1.326527e-10	6.22288554888889e-8	3.463535	38	0.01601349	21	0.001177587574	2.343442	28	76	0.009485095	
GO Molecular Function	nuclease activity	12	2.596276e-8	0.000009134564393333333	2.110928	67	0.0282343	51	0.045578650670588236	1.560189	52	212	0.01761518	
GO Molecular Function	snRNA binding	15	9.843604e-8	0.000027706464058666665	5.073651	17	0.007163928	45	0.03345176916444444	2.510831	15	38	0.005081301	
GO Molecular Function	rRNA binding	16	1.279515e-7	0.0000337632020625	4.252566	20	0.00842815	52	0.04610367977307693	2.120257	20	60	0.006775068	
GO Molecular Function	snRNP binding	18	2.342103e-7	0.00005493532703333333	17.42384	7	0.002949853	34	0.011310251228235294	5.452091	6	7	0.00203252	
GO Molecular Function	3'-5' exonuclease activity	20	4.820375e-7	0.00010175811625000001	3.37502	24	0.01011378	31	0.004236450135483871	2.544309	20	50	0.006775068	
GO Molecular Function	protein carboxyl O-methyltransferase activity	35	0.00005210772	0.006285679824	7.544105	7	0.002949853	49	0.04303195953061224	5.300644	5	6	0.001693767	
Mouse Phenotype Single KO	chromosome breakage	11	0.0000296036	0.02464365138181818	2.566673	25	0.01053519	129	0.0428038215255814	2.158119	19	56	0.006436314	
Mouse Phenotype	small pancreas	15	0.00004073446	0.025964144804	2.017352	40	0.0168563	127	0.011224757038582677	2.43604	18	47	0.006097561