# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1	7.136409e-19	9.3908006031e-15	2.705304	106	0.01471405	270	0.002337329360111111	1.506387	63	118	0.009466566	
GO Biological Process	nuclear-transcribed mRNA catabolic process	2	3.987665e-18	2.62368418675e-14	2.111435	166	0.02304275	322	0.007352856881987578	1.353744	95	198	0.01427498	
GO Biological Process	mRNA catabolic process	3	4.599662e-18	2.0175650752666666e-14	2.047331	178	0.0247085	303	0.005072955187458746	1.351135	102	213	0.01532682	
GO Biological Process	protein localization to endoplasmic reticulum	7	3.121011e-15	5.867054821285714e-12	2.335438	110	0.01526929	230	0.000960128126826087	1.524513	67	124	0.01006762	
GO Biological Process	protein targeting to ER	8	4.545136e-15	7.476180578e-12	2.593259	89	0.01235425	282	0.0032505991752127656	1.536454	55	101	0.008264463	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	9	2.230011e-14	3.2605238609999995e-11	2.655059	81	0.01124375	365	0.012357804370684932	1.502749	49	92	0.007362885	
GO Biological Process	cotranslational protein targeting to membrane	10	3.489604e-14	4.5919699036e-11	2.578706	84	0.01166019	304	0.005153826236842105	1.525907	53	98	0.007963937	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	11	1.604662e-13	1.9196133870909092e-10	2.375172	93	0.01290949	276	0.00278037130807971	1.531665	57	105	0.008564989	
GO Biological Process	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	34	3.510839e-9	0.0000013587979529705882	6.425759	17	0.0023598	400	0.02306379574875	2.821488	7	7	0.001051841	
GO Biological Process	positive regulation of cytoplasmic translation	37	2.625698e-8	0.000009338259454594595	7.796317	13	0.001804553	400	0.02306379574875	2.821488	7	7	0.001051841	
GO Biological Process	positive regulation of pri-miRNA transcription from RNA polymerase II promoter	139	0.00006238255	0.005905697665107913	2.206822	31	0.004303165	499	0.04586713170541082	1.975041	14	20	0.002103681	
GO Biological Process	deoxyribose phosphate catabolic process	255	0.0005749567	0.029670020452156862	2.467468	18	0.002498612	499	0.04586713170541082	1.975041	14	20	0.002103681	
GO Biological Process	negative regulation of mRNA splicing, via spliceosome	304	0.001013822	0.04388448584868421	2.022731	25	0.003470294	499	0.04586713170541082	1.975041	14	20	0.002103681	
Mouse Phenotype Single KO	abnormal gastrulation movements	37	0.000005015001	0.0012411449772162162	3.789373	17	0.0023598	204	0.011145963242156864	2.821488	8	8	0.001202104	
Mouse Phenotype Single KO	small thyroid gland	80	0.0001142155	0.01307339166875	2.131803	31	0.004303165	259	0.027386840452509654	2.078991	14	19	0.002103681	
Mouse Phenotype Single KO	abnormal head fold morphology	119	0.0005656149	0.04352382890168067	2.11069	25	0.003470294	224	0.01606609549017857	2.387413	11	13	0.001652893	
Mouse Phenotype	decreased urine ammonia level	39	0.000009497724	0.0023284035683076923	4.558941	13	0.001804553	464	0.04078347578017241	2.821488	6	6	0.0009015778