# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of viral process	37	6.547314e-8	0.000023285433763783784	2.638991	40	0.03327787	185	0.02414994449891892	1.888025	32	190	0.01910448	
GO Biological Process	positive regulation of viral process	45	2.224053e-7	0.00006503625206	3.138083	28	0.02329451	181	0.021582613892265193	2.263588	21	104	0.01253731	
GO Biological Process	regulation of symbiosis, encompassing mutualism through parasitism	48	3.558264e-7	0.00009754832495	2.375701	43	0.03577371	200	0.0306776490745	1.799795	35	218	0.02089552	
GO Biological Process	regulation of viral life cycle	61	0.000003161346	0.0006819697051475411	2.445519	34	0.02828619	223	0.04357337899730942	1.847827	30	182	0.01791045	
GO Biological Process	cardiac vascular smooth muscle cell development	66	0.000006983074	0.0013922768297878786	13.58936	6	0.004991681	220	0.04238939174954546	11.21015	3	3	0.001791045	
GO Biological Process	positive regulation of viral life cycle	67	0.000007534646	0.001479826965880597	2.855475	24	0.01996672	187	0.024886638571122995	2.287786	20	98	0.0119403	
GO Biological Process	secondary alcohol metabolic process	70	0.000009358907	0.0017593408173285714	2.624892	27	0.02246256	213	0.03766047109624413	2.107891	22	117	0.01313433	
GO Biological Process	cholesterol metabolic process	71	0.00001385671	0.002568175308309859	2.62172	26	0.02163062	233	0.047085076341201716	2.101903	21	112	0.01253731	
GO Biological Process	cellular response to vascular endothelial growth factor stimulus	83	0.00005476324	0.008682282833253011	3.251596	16	0.01331115	142	0.011823611706338027	3.865569	10	29	0.005970149	
GO Biological Process	positive regulation by host of viral transcription	84	0.0000555422	0.008700950116666667	5.46217	9	0.007487521	111	0.0031284929752252253	5.605075	8	16	0.004776119	
GO Biological Process	positive regulation of viral transcription	92	0.00008036522	0.011494847065	3.936099	12	0.009983361	236	0.048896056076271184	2.935991	11	42	0.006567164	
GO Biological Process	protein methylation	93	0.00008229407	0.01164416846376344	2.101638	33	0.02745424	117	0.004461569072307692	2.275745	27	133	0.0161194	
GO Biological Process	regulation of cyclin-dependent protein serine/threonine kinase activity	103	0.0001293915	0.016530706296116505	2.550669	21	0.01747088	172	0.017487928470930232	2.491144	18	81	0.01074627	
GO Biological Process	regulation of cyclin-dependent protein kinase activity	117	0.0003023812	0.03400883940854701	2.391376	21	0.01747088	194	0.02907368452371134	2.373914	18	85	0.01074627	
GO Biological Process	positive regulation of signal transduction by p53 class mediator	128	0.0003771537	0.03877316826796875	4.208881	9	0.007487521	175	0.020894950517142855	4.270533	8	21	0.004776119	
GO Cellular Component	transcriptional repressor complex	21	0.000004037997	0.00033226946742857143	2.638555	29	0.02412646	14	0.00007330422857142858	3.106427	23	83	0.01373134	
GO Cellular Component	ruffle membrane	30	0.00008482458	0.004885895808	2.443808	24	0.01996672	18	0.0022160553599999996	2.675149	21	88	0.01253731	
GO Cellular Component	collagen type VI trimer	31	0.0001449133	0.008077747819354839	7.831941	6	0.004991681	35	0.034989092022857146	11.21015	3	3	0.001791045	
GO Cellular Component	euchromatin	39	0.0006244972	0.027670029784615382	3.128801	12	0.009983361	26	0.02815013686153846	3.397015	10	33	0.005970149	
GO Cellular Component	histone deacetylase complex	41	0.0007125263	0.030030376741463416	2.186771	22	0.01830283	19	0.004598987418947369	2.989373	16	60	0.009552239	
GO Molecular Function	histone deacetylase binding	7	0.000003395143	0.0020477562494285715	2.476343	33	0.02745424	21	0.000034545831438095234	2.906335	28	108	0.01671642	
Mouse Phenotype Single KO	increased mammary adenocarcinoma incidence	2	0.000003281479	0.0150242516015	7.856675	9	0.007487521	156	0.02363763913525641	4.076418	8	22	0.004776119	
Mouse Phenotype Single KO	interrupted aortic arch	3	0.000005968899	0.018219069381000003	3.068892	22	0.01830283	26	0.0008343752742307693	4.130055	14	38	0.008358209	
Mouse Phenotype Single KO	abnormal mean corpuscular volume	5	0.000009099312	0.016664479996800003	2.084383	43	0.03577371	138	0.019816530989855075	1.842043	35	213	0.02089552	
Mouse Phenotype Single KO	abnormal mean corpuscular hemoglobin	10	0.00002340218	0.021429376226	2.132259	37	0.03078203	153	0.022535257300653595	1.92174	30	175	0.01791045	
Mouse Phenotype Single KO	interrupted aorta	11	0.00002349073	0.019554964964545455	2.801687	22	0.01830283	36	0.0012193100007222223	3.923552	14	40	0.008358209	
Mouse Phenotype Single KO	abnormal fourth pharyngeal arch artery morphology	18	0.00004915694	0.025007227754444444	3.637049	14	0.01164725	129	0.017486966734108527	4.90444	7	16	0.004179104	
Mouse Phenotype Single KO	increased sensitivity to induced cell death	22	0.00006647388	0.027668241780000002	2.294611	28	0.02329451	163	0.02779328145766871	1.996328	26	146	0.01552239	
Mouse Phenotype Single KO	abnormal sixth pharyngeal arch artery morphology	31	0.0001579044	0.046642922283870965	3.432471	13	0.01081531	76	0.0055358727840789474	5.275364	8	17	0.004776119	
Mouse Phenotype Single KO	decreased NK cell degranulation	34	0.0001841819	0.04960451936176471	9.838999	5	0.004159734	135	0.019881264639259256	8.968119	4	5	0.00238806	
Mouse Phenotype	abnormal interventricular groove morphology	4	0.000002744194	0.0065593097085	6.959656	10	0.008319468	252	0.01975675934285714	6.227861	5	9	0.002985075	
Mouse Phenotype	increased body temperature	5	0.000003646688	0.006973196793599999	4.077488	16	0.01331115	275	0.024766056473454548	3.2029	10	35	0.005970149	
Mouse Phenotype	abnormal third pharyngeal arch artery morphology	10	0.00002324091	0.022220634051000002	3.9027	14	0.01164725	362	0.04440775484254143	3.736716	7	21	0.004179104	
Mouse Phenotype	interrupted aortic arch	21	0.00009293059	0.042309970047142854	2.42885	24	0.01996672	51	0.00039996587541176474	3.736716	16	48	0.009552239	
Mouse Phenotype	abnormal liver vasculature morphology	24	0.0001228107	0.0489247126125	2.08272	32	0.0266223	233	0.015172006211587983	2.182507	22	113	0.01313433