# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nephron development	48	2.856961e-218	7.832239541458334e-216	12.48165	286	0.2823297	8	0.0256844270475	3.6414	15	122	0.02365931	
GO Biological Process	kidney development	92	2.265885e-157	3.240954425543478e-155	6.923516	297	0.2931885	10	0.022607530452	2.692429	23	253	0.0362776	
GO Biological Process	renal system development	99	2.377412e-152	3.160036818989899e-150	6.499245	301	0.2971372	4	0.016685506728	2.752483	25	269	0.03943218	
GO Biological Process	urogenital system development	108	1.091847e-143	1.3303346919444445e-141	5.946713	304	0.3000987	1	0.019174676326999998	2.745921	28	302	0.04416404	
GO Biological Process	positive regulation of cell differentiation	132	1.622388e-124	1.6173487645454547e-122	3.455571	423	0.4175716	6	0.026779902831666664	1.838279	54	870	0.0851735	
GO Biological Process	positive regulation of developmental process	160	3.160638e-108	2.599427215125e-106	2.808572	469	0.4629812	13	0.024317153805384614	1.664411	68	1210	0.1072555	
GO Biological Process	embryo development	170	3.948729e-102	3.05654852417647e-100	3.257638	382	0.3770977	29	0.03159229055310345	1.73446	53	905	0.08359621	
GO Biological Process	regulation of cell differentiation	176	1.624952e-96	1.2149286004545455e-94	2.452029	504	0.4975321	18	0.022328015746666666	1.541061	87	1672	0.137224	
GO Biological Process	positive regulation of multicellular organismal process	191	7.257496e-84	5.000072767748691e-82	2.454878	454	0.4481737	30	0.032373363871	1.551352	77	1470	0.1214511	
GO Biological Process	tissue development	199	1.612282e-81	1.0661315998994975e-79	2.452279	445	0.4392892	11	0.021953351103636363	1.567408	86	1625	0.1356467	
GO Biological Process	embryonic placenta development	334	1.374899e-21	5.416855072155688e-20	4.982927	55	0.05429418	5	0.022969008182	4.326038	13	89	0.02050473	
GO Biological Process	regulation of osteoblast differentiation	385	2.475018e-14	8.459418665454545e-13	3.22796	58	0.05725568	32	0.0322197498171875	3.532269	13	109	0.02050473	
GO Biological Process	nephron epithelium development	516	3.449419e-8	8.796686942054263e-7	2.462813	47	0.04639684	36	0.03752544719444444	3.663924	12	97	0.01892744	
GO Biological Process	kidney epithelium development	524	5.867049e-8	0.0000014733682784541984	2.196589	57	0.05626851	16	0.022880910321875	3.470709	15	128	0.02365931	
GO Biological Process	mesoderm formation	574	4.193917e-7	0.000009614591254878048	2.89804	30	0.029615	33	0.03126780171333333	4.420406	10	67	0.01577287	
GO Biological Process	potassium ion transmembrane transport	579	4.934268e-7	0.000011214167981347151	2.197354	49	0.04837117	15	0.022467781872	3.186609	17	158	0.02681388	
GO Biological Process	mesoderm morphogenesis	602	0.000001160405	0.000025365065440199336	2.754788	30	0.029615	35	0.03804936129142857	4.292278	10	69	0.01577287	
GO Biological Process	endocardial cushion development	613	0.000002212238	0.00004748913514192496	3.072519	24	0.023692	19	0.022327228515263156	6.235099	8	38	0.0126183	
GO Biological Process	potassium ion transport	632	0.000004444806	0.00009254620593987341	2.026638	49	0.04837117	37	0.03833259377837838	2.844544	17	177	0.02681388	
GO Biological Process	mesenchyme morphogenesis	671	0.00001822041	0.000357320976438152	2.698802	24	0.023692	34	0.03188519361117647	5.510087	8	43	0.0126183	
GO Molecular Function	transcription factor binding	21	7.873109e-35	1.5828698189523808e-32	2.842993	173	0.1707799	26	0.046942583053846146	1.896362	34	531	0.05362776	
GO Molecular Function	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	30	2.038509e-16	2.868861666e-14	2.44158	104	0.1026654	12	0.021178452693333332	2.486075	23	274	0.0362776	
GO Molecular Function	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	34	9.138051e-15	1.1347309212352941e-12	2.125899	122	0.1204344	19	0.03440834449473684	2.094841	29	410	0.04574132	
GO Molecular Function	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	39	2.174913e-13	2.3544827400000002e-11	2.014705	124	0.1224087	2	0.0017731971466999998	2.517421	34	400	0.05362776	
GO Molecular Function	RNA polymerase II core promoter proximal region sequence-specific DNA binding	42	2.756747e-12	2.7711871033333333e-10	2.091192	104	0.1026654	24	0.044430058675	2.13306	26	361	0.04100946	
GO Molecular Function	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	59	1.5687e-9	1.1225510847457627e-7	2.544493	53	0.05231984	20	0.03470021691	3.117549	14	133	0.02208202	
GO Molecular Function	ATPase activity, coupled	65	2.738267e-9	1.7786097344615384e-7	2.342401	60	0.05923001	21	0.03440811381904762	2.270931	24	313	0.03785489	
GO Molecular Function	voltage-gated cation channel activity	69	1.102391e-8	6.745354785507245e-7	2.473692	50	0.04935834	8	0.00835421917	3.458887	16	137	0.02523659	
GO Molecular Function	voltage-gated potassium channel activity	73	4.130868e-8	0.0000023891129720547947	2.681287	40	0.03948667	15	0.026107997970666666	3.70209	12	96	0.01892744	
GO Molecular Function	voltage-gated ion channel activity	85	0.000001063893	0.00005284419112941176	2.082146	52	0.05133268	25	0.04850503808	2.622314	17	192	0.02681388	
GO Molecular Function	potassium ion transmembrane transporter activity	86	0.000001261359	0.00006192392672093023	2.124118	49	0.04837117	11	0.015889911523636363	3.070026	17	164	0.02681388	
Mouse Phenotype	decreased embryo size	83	2.44279e-150	2.8139174927710842e-148	4.985107	361	0.3563672	2	0.0359693663925	2.047458	43	622	0.06782334	
Mouse Phenotype	abnormal embryo size	102	2.919996e-138	2.7370668388235292e-136	4.494925	365	0.3603159	13	0.027918509794615385	1.866259	46	730	0.07255521	
Mouse Phenotype	abnormal cranium morphology	103	7.069835e-138	6.56259149854369e-136	3.92301	409	0.4037512	11	0.029847947007272727	1.87396	46	727	0.07255521	
Mouse Phenotype	abnormal craniofacial bone morphology	108	5.970195e-136	5.2852809625e-134	3.861442	410	0.4047384	8	0.03281637566625	1.875992	47	742	0.07413249	
Mouse Phenotype	abnormal viscerocranium morphology	111	5.678579e-134	4.891251695405406e-132	4.560963	351	0.3464956	17	0.02659398336529412	2.034736	36	524	0.05678233	
Mouse Phenotype	abnormal prenatal body size	125	1.455965e-117	1.1136385092e-115	3.797294	369	0.3642646	28	0.04986297110357143	1.7048	51	886	0.08044164	
Mouse Phenotype	abnormal jaw morphology	131	3.240288e-110	2.364915539541985e-108	4.42071	304	0.3000987	24	0.040633373575	2.055824	32	461	0.05047319	
Mouse Phenotype	abnormal embryonic growth/weight/body size	132	9.339796e-109	6.764984057272728e-107	3.435406	381	0.3761106	27	0.04902069885555555	1.660196	56	999	0.08832808	
Mouse Phenotype	embryonic lethality during organogenesis	138	5.28448e-105	3.6612256e-103	3.355782	379	0.3741362	21	0.042403572237142854	1.695026	55	961	0.08675079	
Mouse Phenotype	abnormal craniofacial morphology	150	5.635115e-97	3.591822301e-95	2.781089	436	0.4304047	5	0.046331669022	1.679299	66	1164	0.1041009	
Mouse Phenotype	craniofacial phenotype	151	7.315752e-97	4.632179130596027e-95	2.778895	436	0.4304047	7	0.03680076705	1.673547	66	1168	0.1041009	
Mouse Phenotype	abnormal facial morphology	180	1.322596e-83	7.025189086666666e-82	3.110674	340	0.3356367	18	0.029906733636666665	1.821971	47	764	0.07413249	
Mouse Phenotype	abnormal skeleton morphology	182	3.461306e-83	1.8183267398901097e-81	2.190851	524	0.5172754	19	0.03624723547105263	1.442013	104	2136	0.1640379	
Mouse Phenotype	abnormal head morphology	185	1.111493e-80	5.744315985405405e-79	2.841376	367	0.3622902	15	0.026301048948000002	1.747768	55	932	0.08675079	
Mouse Phenotype	abnormal digestive system morphology	202	9.901033e-76	4.6863255699504954e-74	2.689506	373	0.3682132	1	0.064889560461	1.739106	67	1141	0.1056782	
Mouse Phenotype	digestive/alimentary phenotype	208	2.617391e-70	1.2031190072596152e-68	2.465387	394	0.3889437	12	0.0284085594625	1.585874	77	1438	0.1214511	
Mouse Phenotype	muscle phenotype	215	1.430729e-64	6.362418590232559e-63	2.313446	403	0.3978282	22	0.041706372735	1.53879	77	1482	0.1214511	
Mouse Phenotype	small ectoplacental cone	408	4.223763e-13	9.897891677205884e-12	11.59374	17	0.01678184	4	0.0453725620875	9.87224	6	18	0.009463722	
Mouse Phenotype	abnormal pancreas development	488	2.551456e-10	4.998866970491803e-9	3.498512	36	0.03553801	16	0.027546215026875	5.22648	9	51	0.01419558	
Mouse Phenotype	abnormal endoderm development	505	1.463682e-9	2.7711413073267326e-8	3.771231	30	0.029615	29	0.049375179951724135	4.517805	9	59	0.01419558