# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process	62	7.82342e-63	1.6604578029032256e-60	2.009883	703	0.02193448	142	8.871116682746477e-12	1.305079	182	198	0.01376181	
GO Biological Process	secondary alcohol metabolic process	85	3.455387e-54	5.349345592117647e-52	2.063672	566	0.01765991	607	0.013736597720757825	1.189243	98	117	0.007410208	
GO Biological Process	cholesterol metabolic process	91	4.503807e-52	6.512702891538461e-50	2.061037	545	0.01700468	740	0.027543760849999998	1.17895	93	112	0.007032136	
GO Biological Process	xenobiotic metabolic process	116	1.00703e-44	1.1423713594827586e-42	2.185808	406	0.01266771	801	0.04070840969163545	1.176415	87	105	0.00657845	
GO Biological Process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	122	1.121108e-43	1.209234440327869e-41	2.383046	330	0.01029641	501	0.004384463231936128	1.271473	60	67	0.004536862	
GO Biological Process	endoplasmic reticulum unfolded protein response	125	6.82622e-43	7.1860983184e-41	2.078473	437	0.01363495	466	0.0022837097170171675	1.220539	98	114	0.007410208	
GO Biological Process	protein import into mitochondrial matrix	152	2.37305e-40	2.0544055888157894e-38	4.856932	112	0.00349454	807	0.04198642293060718	1.419811	17	17	0.001285444	
GO Biological Process	regulation of cholesterol metabolic process	184	5.126854e-38	3.666536510108696e-36	2.428709	275	0.008580343	473	0.0025926395949682876	1.312655	49	53	0.003705104	
GO Biological Process	mitochondrial transmembrane transport	192	1.295483e-37	8.878781665104165e-36	2.215413	329	0.01026521	677	0.020518379700147714	1.214537	71	83	0.00536862	
GO Biological Process	regulation of plasma lipoprotein particle levels	225	4.089914e-33	2.391963481155555e-31	2.089999	329	0.01026521	841	0.0495663072841855	1.205867	62	73	0.004688091	
GO Biological Process	snRNA metabolic process	241	4.027508e-32	2.1990862146058092e-30	2.186302	287	0.008954758	315	0.00005002145291111111	1.304245	79	86	0.005973535	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	245	5.742845e-32	3.0844937695918367e-30	2.007816	350	0.01092044	236	0.0000011792599549576272	1.299488	108	118	0.008166352	
GO Biological Process	gluconeogenesis	252	1.080575e-31	5.642573978174603e-30	2.371783	238	0.007425897	651	0.016568321042396316	1.293606	41	45	0.003100189	
GO Biological Process	regulation of cholesterol biosynthetic process	258	1.773234e-31	9.044180699999999e-30	2.398825	231	0.007207488	455	0.0019633826662197804	1.352201	40	42	0.003024575	
GO Biological Process	hexose biosynthetic process	259	2.423319e-31	1.231214467992278e-29	2.293606	252	0.007862715	552	0.008750847042210146	1.301493	44	48	0.003327032	
GO Biological Process	monosaccharide biosynthetic process	261	2.842661e-31	1.4332021493869732e-29	2.237815	265	0.008268331	543	0.007638120951197053	1.288347	49	54	0.003705104	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	270	9.463219e-31	4.6120925489259257e-29	2.111282	297	0.009266771	823	0.0455257110291616	1.214041	59	69	0.004461248	
GO Biological Process	ncRNA transcription	300	3.750376e-29	1.6450399261333333e-27	2.004029	319	0.009953198	440	0.001579440377159091	1.250051	81	92	0.006124764	
GO Biological Process	protein transmembrane transport	312	3.966939e-28	1.6731073814423078e-26	2.135706	263	0.008205928	405	0.0009243271496296296	1.307128	58	63	0.004385633	
GO Biological Process	snRNA transcription from RNA polymerase II promoter	318	7.467663e-28	3.0901565225471694e-26	2.133115	261	0.008143526	462	0.0022484532652380955	1.27783	63	70	0.004763705	
GO Cellular Component	protein-lipid complex	93	5.241232e-22	9.7385472e-21	2.126907	204	0.006365055	145	0.021450319448275863	1.284591	38	42	0.002873346	
GO Cellular Component	plasma lipoprotein particle	102	4.977414e-20	8.432324894117647e-19	2.089637	192	0.00599064	158	0.0329142768607595	1.27783	36	40	0.002722117	
GO Cellular Component	CCR4-NOT complex	130	8.728545e-16	1.1602250584615383e-14	2.644854	91	0.002839314	168	0.03761664685714286	1.419811	16	16	0.00120983	
GO Cellular Component	endoribonuclease complex	133	3.096337e-15	4.0229100270676693e-14	2.303468	114	0.003556942	160	0.035027899200000004	1.321893	27	29	0.002041588	
GO Cellular Component	U12-type spliceosomal complex	182	6.838811e-11	6.493112861538462e-10	2.219569	84	0.002620905	137	0.016463425401459855	1.365203	25	26	0.001890359	
GO Molecular Function	snRNA binding	36	9.413174e-26	1.1039561285555555e-23	2.916858	132	0.004118565	88	0.0013177269806818183	1.382448	37	38	0.002797732	
GO Molecular Function	rRNA binding	55	7.92263e-21	6.081698883636363e-19	2.377211	151	0.004711388	145	0.026366777259310345	1.254166	53	60	0.004007561	
Human Phenotype	Glycosuria	22	2.348756e-27	7.124203994545455e-25	2.625153	168	0.00524181	269	0.012488837025650559	1.370852	28	29	0.002117202	
Human Phenotype	Hepatic fibrosis	31	2.814542e-23	6.058528634193548e-21	2.289863	184	0.00574103	212	0.003931432574056604	1.34882	38	40	0.002873346	
Mouse Phenotype Single KO	abnormal circulating ketone body level	47	1.308337e-38	2.5490301934042555e-36	2.201095	343	0.01070203	221	0.005383661336651584	1.327215	43	46	0.003251418	
Mouse Phenotype Single KO	increased circulating ketone body level	97	9.993892e-28	9.434440107628866e-26	2.054942	284	0.008861154	331	0.028060533746223568	1.333762	31	33	0.002344045	
Mouse Phenotype Single KO	spontaneous chromosome breakage	315	2.017717e-14	5.865471291746032e-13	2.211302	117	0.003650546	374	0.043796780254010695	1.363019	24	25	0.001814745	
Mouse Phenotype Single KO	abnormal hypoglossal nerve topology	594	5.080574e-9	7.832123925589226e-8	2.037219	82	0.002558502	376	0.044149842303191494	1.419811	18	18	0.001361059	
Mouse Phenotype	abnormal circulating ketone body level	82	6.222781e-38	7.255610870853658e-36	2.088638	380	0.01185647	189	0.0003463456567936508	1.34375	53	56	0.004007561	
Mouse Phenotype	abnormal bile salt level	185	5.247979e-24	2.712212282108108e-22	2.066738	240	0.0074883	555	0.03708653328108109	1.301493	33	36	0.002495274	
Mouse Phenotype	lymphoid hyperplasia	212	4.220751e-22	1.9035188825943397e-20	2.163629	197	0.006146646	492	0.026429382908536588	1.331073	30	32	0.002268431	
Mouse Phenotype	abnormal hypoglossal nerve topology	772	5.080574e-9	6.292146115803109e-8	2.037219	82	0.002558502	526	0.032951968323193914	1.419811	18	18	0.001361059