# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	147	5.790602e-62	5.183573586258503e-60	2.157982	587	0.01173718	435	0.00001035307466689655	1.19479	114	118	0.007508398	
GO Biological Process	regulation of mitochondrial membrane permeability	158	1.340745e-53	1.1166369275316458e-51	2.057571	566	0.01131728	545	0.00007883433760733945	1.219771	72	73	0.004742146	
GO Biological Process	gene silencing by miRNA	198	4.81544e-45	3.200321967676768e-43	2.309767	364	0.007278253	963	0.013464861346313604	1.208605	43	44	0.002832115	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	230	4.302499e-41	2.4615906235217393e-39	2.049172	434	0.008677917	572	0.00013839819513811189	1.196385	89	92	0.005861819	
GO Biological Process	posttranscriptional gene silencing by RNA	235	1.073767e-40	6.01263827787234e-39	2.124211	394	0.007878109	813	0.004112577576137761	1.212463	50	51	0.003293157	
GO Biological Process	posttranscriptional gene silencing	239	1.663433e-40	9.158625458995817e-39	2.112973	397	0.007938095	787	0.003495453427573062	1.212929	51	52	0.00335902	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	241	8.666385e-40	4.731990050414937e-38	2.00901	441	0.008817884	1024	0.019372091243164063	1.165019	65	69	0.004281104	
GO Biological Process	axonal transport	300	1.416153e-33	6.211719109e-32	2.17151	306	0.006118532	1103	0.030552108080689026	1.205002	38	39	0.002502799	
GO Biological Process	axo-dendritic transport	338	1.235681e-30	4.8107474198224854e-29	2.001783	338	0.006758378	907	0.00972522786427784	1.209827	45	46	0.002963841	
GO Biological Process	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	385	2.219705e-28	7.586778725974027e-27	2.000825	312	0.006238503	843	0.005967672060854092	1.236712	37	37	0.002436936	
GO Biological Process	production of miRNAs involved in gene silencing by miRNA	398	1.174509e-27	3.883257269095478e-26	2.25092	230	0.004598896	1143	0.0369828456727909	1.236712	27	27	0.001778305	
GO Biological Process	cytoplasmic translation	728	5.593123e-17	1.010987713695055e-15	2.007402	177	0.003539151	988	0.01590182573279352	1.207951	42	43	0.002766252	
GO Cellular Component	axon cytoplasm	74	8.176014e-34	1.9092097556756757e-32	2.172426	308	0.006158522	223	0.016410103103139013	1.205794	39	40	0.002568662	
Mouse Phenotype Single KO	abnormal liver sinusoid morphology	47	1.608406e-55	3.1336539876595747e-53	2.079465	572	0.01143726	497	0.010968245387726358	1.180498	63	66	0.004149378	
Mouse Phenotype Single KO	increased squamous cell carcinoma incidence	269	1.168768e-19	3.978590548698885e-18	2.06008	195	0.003899064	749	0.04858545266755675	1.236712	26	26	0.001712442	
Mouse Phenotype	abnormal liver sinusoid morphology	68	1.379671e-71	1.9398580045588233e-69	2.06147	758	0.01515636	524	0.0013538819382251908	1.189146	75	78	0.004939735