# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	chordate embryonic development	113	1.327018e-88	1.545330076283186e-86	2.984978	414	0.2067932	108	0.031155102188888888	1.497894	75	555	0.04427391	
GO Biological Process	embryo development ending in birth or egg hatching	116	6.979561e-88	7.917589930948276e-86	2.968277	414	0.2067932	117	0.03774930202905983	1.48452	75	560	0.04427391	
GO Biological Process	macromolecular complex assembly	143	2.375397e-68	2.1858635750349652e-66	2.17758	535	0.2672328	87	0.009010440721494253	1.316596	179	1507	0.1056671	
GO Biological Process	in utero embryonic development	320	1.292518e-17	5.315076363125e-16	2.125773	153	0.07642358	80	0.00402228850175	1.806087	51	313	0.03010626	
GO Biological Process	mitotic cell cycle checkpoint	560	0.00001193603	0.00028047539066071425	2.04817	44	0.02197802	118	0.03896201472881356	2.008585	27	149	0.01593861	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	581	0.00002590282	0.0005866698939414803	2.479611	27	0.01348651	116	0.03606245503534483	2.160522	23	118	0.01357733	
GO Biological Process	mitochondrial genome maintenance	797	0.0010472	0.017289968381430366	3.351674	10	0.004995005	112	0.03529354241607143	4.222635	8	21	0.00472255	
GO Cellular Component	perinuclear region of cytoplasm	7	3.225827e-92	7.963184365714287e-90	3.211116	391	0.1953047	29	0.0172178515862069	1.448723	86	658	0.05076741	
GO Cellular Component	chromatin	28	4.160714e-26	2.567754925714286e-24	2.344557	188	0.09390609	34	0.042712058541176476	1.482484	65	486	0.03837072	
GO Cellular Component	nuclear chromatin	31	1.188748e-23	6.626311432258065e-22	2.588183	142	0.07092907	30	0.02572535808	1.648631	47	316	0.02774498	
GO Cellular Component	nuclear chromosome part	39	1.091812e-16	4.8375670153846154e-15	2.006815	165	0.08241758	36	0.041613979200000005	1.466421	68	514	0.04014168	
GO Cellular Component	COPI vesicle coat	133	0.001153937	0.014992504781954888	3.9627	8	0.003996004	31	0.029268105909677423	5.115884	6	13	0.003541913	
GO Cellular Component	glycine cleavage complex	167	0.004823288	0.049908033916167674	8.992416	3	0.001498501	25	0.0045640668672	11.08442	4	4	0.002361275	
GO Molecular Function	transcription factor binding	24	8.684598e-27	1.5277655314999998e-24	2.070496	249	0.1243756	7	0.0001468263226857143	1.753467	84	531	0.04958678	
Mouse Phenotype Single KO	abnormal fibroblast physiology	22	2.578234e-155	1.0731313062727274e-152	7.118412	303	0.1513487	25	0.047621234895999995	1.900186	36	210	0.02125148	
Mouse Phenotype Single KO	decreased embryo size	45	5.181493e-87	1.0543762533555556e-84	3.194256	373	0.1863137	5	0.000008491148745000001	1.895149	86	503	0.05076741	
Mouse Phenotype Single KO	abnormal embryo size	49	8.078302e-81	1.5096532941632651e-78	2.920003	392	0.1958042	4	0.0000034404543045	1.829291	101	612	0.0596222	
Mouse Phenotype Single KO	embryonic lethality	57	2.451818e-72	3.938824109824562e-70	2.076705	612	0.3056943	12	0.0014914051684999999	1.372356	195	1575	0.1151122	
Mouse Phenotype Single KO	embryonic lethality during organogenesis	58	3.306351e-72	5.22004415637931e-70	2.516608	440	0.2197802	17	0.018134140360588233	1.487841	100	745	0.05903188	
Mouse Phenotype Single KO	abnormal prenatal body size	62	9.103109e-66	1.3444704695645163e-63	2.498604	409	0.2042957	8	0.00001319115068875	1.696139	114	745	0.06729634	
Mouse Phenotype Single KO	abnormal embryonic growth/weight/body size	64	5.382824e-63	7.701643651249999e-61	2.370865	429	0.2142857	7	0.00001392762694142857	1.660637	123	821	0.07260921	
Mouse Phenotype Single KO	abnormal prenatal growth/weight/body size	81	1.239726e-49	1.4015025903703702e-47	2.052653	453	0.2262737	6	0.000014717051039333333	1.594639	143	994	0.08441558	
Mouse Phenotype Single KO	abnormal trophoblast layer morphology	227	3.0795e-11	1.2422458810572687e-9	2.44636	70	0.03496503	29	0.04885319494137931	2.1076	27	142	0.01593861	
Mouse Phenotype Single KO	abnormal placenta labyrinth morphology	284	3.754887e-8	0.0000012106866288380282	2.073709	68	0.03396603	22	0.050361835090909086	2.073858	29	155	0.01711924	
Mouse Phenotype Single KO	decreased fibroblast proliferation	389	0.00002150698	0.0005062709919280206	2.147778	37	0.01848152	24	0.04756336570833333	2.34478	22	104	0.01298701	
Mouse Phenotype	abnormal fibroblast physiology	42	1.412661e-147	3.215821862142857e-145	6.428603	311	0.1553447	22	0.007453112405454545	1.927724	44	253	0.02597403	
Mouse Phenotype	decreased embryo size	90	1.356819e-84	1.441394051e-82	2.892764	414	0.2067932	8	0.00006926577596625	1.728599	97	622	0.05726092	
Mouse Phenotype	abnormal embryo size	94	3.014072e-79	3.0656959991489367e-77	2.691899	432	0.2157842	6	0.000040749236959999995	1.685439	111	730	0.06552538	
Mouse Phenotype	abnormal embryonic growth/weight/body size	114	9.097513e-68	7.629940508157894e-66	2.262977	496	0.2477522	5	0.000014349385912800001	1.597754	144	999	0.0850059	
Mouse Phenotype	abnormal prenatal body size	119	2.048388e-65	1.6457678712605045e-63	2.348387	451	0.2252747	12	0.00011727506665	1.576339	126	886	0.07438017	
Mouse Phenotype	embryonic lethality during organogenesis	133	5.980743e-58	4.29938976112782e-56	2.141548	478	0.2387612	16	0.0014623878159375	1.487918	129	961	0.07615112	
Mouse Phenotype	abnormal prenatal growth/weight/body size	142	6.084616e-55	4.096831941971831e-53	2.002176	521	0.2602398	4	0.000014887404417	1.543635	166	1192	0.09799292	
Mouse Phenotype	abnormal trophoblast layer morphology	367	2.638763e-10	6.874444970844686e-9	2.261965	74	0.03696304	31	0.024500802706451615	2.091399	30	159	0.01770956	
Mouse Phenotype	decreased fibroblast proliferation	496	0.000004390907	0.00008464004400604839	2.157082	43	0.02147852	20	0.005340535575	2.387413	28	130	0.01652893