# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process	6	6.621591e-17	1.45222526615e-13	2.170927	144	0.023692	91	0.00005564938207912088	1.516363	100	198	0.01598977	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	11	1.456331e-15	1.742169057181818e-12	2.661987	88	0.01447845	111	0.00010479055842432434	1.653864	65	118	0.01039335	
GO Biological Process	mRNA catabolic process	13	3.901535e-15	3.9492537742307694e-12	2.031268	149	0.02451464	97	0.000060420850834020616	1.494151	106	213	0.01694915	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	15	6.086381e-15	5.3393791719333334e-12	2.874974	74	0.01217506	79	0.000027736307002531642	1.794912	55	92	0.008794372	
GO Biological Process	viral gene expression	16	7.755435e-15	6.3783605728125e-12	2.520457	92	0.01513656	208	0.0014525131951923077	1.536661	65	127	0.01039335	
GO Biological Process	protein targeting to ER	18	3.137155e-14	2.293434591388889e-11	2.693788	78	0.01283317	100	0.000069834365594	1.72415	58	101	0.009274065	
GO Biological Process	viral transcription	22	9.23939e-14	5.5264151368181817e-11	2.51306	85	0.01398486	178	0.0008080853187640448	1.594194	60	113	0.00959386	
GO Biological Process	cotranslational protein targeting to membrane	24	1.428131e-13	7.830323262083332e-11	2.692571	74	0.01217506	136	0.0002678148707205882	1.68502	55	98	0.008794372	
GO Biological Process	multi-organism metabolic process	27	2.44313e-13	1.1907091729629632e-10	2.212894	106	0.01743995	306	0.009190572424836601	1.429714	70	147	0.01119284	
GO Biological Process	translational initiation	28	3.335173e-13	1.5674121966785713e-10	2.240561	102	0.01678184	125	0.000180844979176	1.574685	75	143	0.01199232	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	33	2.90155e-12	1.157015043939394e-9	2.421671	80	0.01316222	96	0.00005892761946041667	1.715656	60	105	0.00959386	
GO Biological Process	protein localization to endoplasmic reticulum	35	1.039963e-11	3.909963747714286e-9	2.239642	89	0.01464297	120	0.00016785455912499998	1.622264	67	124	0.01071314	
GO Biological Process	ER-nucleus signaling pathway	92	2.745479e-7	0.00003926930234891304	2.584902	38	0.006252057	156	0.0003755745618076923	2.14457	25	35	0.003997442	
GO Biological Process	negative regulation of endoplasmic reticulum unfolded protein response	482	0.001293557	0.03531517959128631	2.876455	12	0.001974334	236	0.0028017384484745763	3.002398	9	9	0.001439079	
GO Cellular Component	ribosomal subunit	16	1.588609e-18	1.71569772e-16	2.409855	128	0.02105956	50	0.000020697092351999998	1.525543	94	185	0.01503038	
GO Cellular Component	large ribosomal subunit	25	6.578867e-13	4.5473128704e-11	2.497117	80	0.01316222	65	0.0005883696443076923	1.566469	60	115	0.00959386	
GO Cellular Component	cytosolic ribosome	28	2.719189e-11	1.6781280685714284e-9	2.185945	90	0.0148075	37	3.4921955286486486e-7	1.796078	67	112	0.01071314	
GO Cellular Component	cytosolic large ribosomal subunit	32	2.697489e-9	1.45664406e-7	2.562889	52	0.008555446	46	0.00000938377627826087	1.968786	40	61	0.006395907	
GO Cellular Component	cytosolic small ribosomal subunit	53	0.0000106271	0.00034648356226415095	2.319797	34	0.005593945	120	0.0426511296	1.637672	24	44	0.003837544	
GO Molecular Function	structural constituent of ribosome	4	1.11776e-14	1.1797956799999999e-11	2.277357	111	0.01826259	43	0.0007563845551162789	1.501199	81	162	0.01295171	
Mouse Phenotype Single KO	abnormal B-2 B cell morphology	42	2.447019e-9	5.335084043571429e-7	3.451335	33	0.005429418	307	0.011861288787947883	2.14457	15	21	0.002398465	
Mouse Phenotype Single KO	abnormal B cell apoptosis	63	8.216993e-8	0.00001194333411126984	2.151832	60	0.009871668	495	0.04611711236565656	1.693661	22	39	0.003517749	
Mouse Phenotype Single KO	absent mature B cells	76	2.786377e-7	0.000033572176564473684	2.245793	50	0.00822639	389	0.025137754028277632	1.801439	21	35	0.003357851	
Mouse Phenotype Single KO	abnormal cell cycle checkpoint function	88	8.302976e-7	0.0000863981264	2.12375	52	0.008555446	337	0.01910233074925816	1.674415	29	52	0.004637032	
Mouse Phenotype Single KO	impaired conditioned place preference behavior	120	0.000007893429	0.000602334411275	2.09186	44	0.007239223	113	0.0001784564781238938	2.401919	20	25	0.003197953	
Mouse Phenotype Single KO	decreased T cell apoptosis	149	0.00002228285	0.001369423204362416	2.058971	41	0.00674564	344	0.019222776349709304	1.901519	19	30	0.003038056	
Mouse Phenotype Single KO	abnormal Peyer's patch T cell area morphology	289	0.0007200773	0.022815736457093425	3.528484	10	0.001645278	497	0.04739683467002012	2.627099	7	8	0.001119284	
Mouse Phenotype Single KO	bicuspid aortic valve	313	0.0009588379	0.028051369489776358	2.102681	23	0.00378414	193	0.0021721651819170983	2.472563	14	17	0.002238567	
Mouse Phenotype Single KO	abnormal carbon dioxide level	368	0.001629768	0.04055376515217391	2.377326	16	0.002632445	375	0.023367491904	2.668799	8	9	0.001279181	
Mouse Phenotype	abnormal B-2 B cell morphology	47	2.610687e-11	5.310803916382979e-9	3.193423	46	0.007568279	509	0.024143497308447934	1.84018	19	31	0.003038056	
Mouse Phenotype	decreased B cell apoptosis	89	3.394506e-8	0.0000036466148164044946	2.770874	39	0.006416584	553	0.031147524965641955	2.001599	14	21	0.002238567	
Mouse Phenotype	abnormal lymph node B cell domain morphology	90	3.718388e-8	0.000003950167518666667	2.141223	64	0.01052978	564	0.0338745382393617	1.58021	30	57	0.00479693	
Mouse Phenotype	increased anti-histone antibody level	107	3.726633e-7	0.00003329938141401869	2.937786	30	0.004935834	383	0.008397928065274153	2.295952	13	17	0.00207867	
Mouse Phenotype	increased follicular B cell number	122	0.000001299557	0.00010184479079508197	2.22784	45	0.007403751	431	0.014908666949651973	1.876499	20	32	0.003197953	
Mouse Phenotype	abnormal leukotriene level	130	0.000001550023	0.00011399823002307692	5.408141	13	0.002138861	662	0.048769216740181275	2.401919	8	10	0.001279181	
Mouse Phenotype	decreased T cell apoptosis	150	0.000004913896	0.00031321173104	2.006886	51	0.008390918	496	0.021669004137096774	1.705908	25	44	0.003997442	
Mouse Phenotype	impaired conditioned place preference behavior	178	0.00002035192	0.0010931725119101123	2.009111	44	0.007239223	221	0.0007480362002714933	2.223999	20	27	0.003197953	
Mouse Phenotype	abnormal Purkinje cell innervation	229	0.0001365958	0.005703023772052401	2.054663	33	0.005429418	545	0.028605722559633028	2.309537	10	13	0.001598977	
Mouse Phenotype	abnormal carbon dioxide level	352	0.001629768	0.04426764729545454	2.377326	16	0.002632445	474	0.019302569772151897	2.668799	8	9	0.001279181