# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of intrinsic apoptotic signaling pathway	39	2.364655e-91	7.978588498717948e-89	2.080547	948	0.02158077	610	0.0012596135639672131	1.149695	141	155	0.009490476	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	40	5.220206e-91	1.7173172688499998e-88	2.360445	716	0.0162994	929	0.018054176329386436	1.140819	102	113	0.006865451	
GO Biological Process	endoplasmic reticulum unfolded protein response	59	1.916625e-83	4.27472345338983e-81	2.331948	672	0.01529776	433	0.00008283751568591223	1.19733	108	114	0.007269301	
GO Biological Process	regulation of DNA-templated transcription in response to stress	62	1.63315e-82	3.4662291693548386e-80	2.197479	754	0.01716445	806	0.008929831275682382	1.147022	108	119	0.007269301	
GO Biological Process	cellular response to topologically incorrect protein	74	6.537587e-79	1.1625419909864864e-76	2.138844	766	0.01743763	370	0.000020571973277567566	1.191109	131	139	0.008817392	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	76	4.168842e-78	7.218130510263158e-76	2.283998	656	0.01493353	1083	0.034470286036934444	1.142842	85	94	0.005721209	
GO Biological Process	liver regeneration	85	5.600934e-74	8.670904765411766e-72	3.008844	379	0.008627755	1079	0.0342145341862836	1.227739	34	35	0.002288484	
GO Biological Process	cellular response to unfolded protein	90	9.602935e-73	1.4040557962777777e-70	2.151022	696	0.01584411	383	0.000025606170251174936	1.201179	115	121	0.007740459	
GO Biological Process	IRE1-mediated unfolded protein response	102	6.747057e-68	8.704365006176471e-66	2.903062	367	0.00835458	865	0.013243896087167629	1.198477	55	58	0.003701959	
GO Biological Process	cellular response to epidermal growth factor stimulus	129	1.022232e-60	1.0427558827906977e-58	2.398001	459	0.01044892	954	0.020624222082809226	1.23059	37	38	0.002490409	
GO Biological Process	platelet-derived growth factor receptor signaling pathway	145	1.36699e-56	1.2405669937931035e-54	2.306636	462	0.01051721	787	0.007312805757560356	1.263849	33	33	0.002221175	
GO Biological Process	response to epidermal growth factor	149	5.846645e-56	5.163490037248322e-54	2.275352	470	0.01069933	826	0.01020970646646489	1.233757	41	42	0.002759642	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	164	1.811579e-51	1.4535712232317074e-49	2.117839	506	0.01151885	635	0.0015659889708976378	1.167453	109	118	0.007336609	
GO Biological Process	regulation of mitochondrial membrane permeability	177	7.185551e-49	5.342071503333334e-47	2.077662	502	0.01142779	478	0.0002050181284665272	1.229223	71	73	0.004778892	
GO Biological Process	negative regulation of Notch signaling pathway	240	9.633956e-41	5.282217791833333e-39	2.416562	299	0.006806593	1176	0.04759669605017008	1.22555	32	33	0.002153867	
GO Biological Process	intrinsic apoptotic signaling pathway in response to DNA damage	253	1.807874e-39	9.403088524110672e-38	2.079796	401	0.009128574	992	0.024776844980846775	1.172265	64	69	0.004307734	
GO Biological Process	cotranslational protein targeting to membrane	255	2.69072e-39	1.3885170384313726e-37	2.059103	409	0.00931069	500	0.00029424866218	1.199367	93	98	0.006259676	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	295	2.900748e-36	1.293930268881356e-34	2.048078	381	0.008673284	570	0.0007781789349473685	1.195161	87	92	0.005855826	
GO Biological Process	protein transmembrane transport	357	1.553172e-32	5.7249832907563025e-31	2.038125	344	0.007830996	472	0.00018807121592372882	1.243788	62	63	0.004173117	
GO Biological Process	regulation of pri-miRNA transcription from RNA polymerase II promoter	360	1.775362e-32	6.48944126611111e-31	2.041355	342	0.007785467	909	0.016181589004400438	1.263849	29	29	0.001951942	
GO Cellular Component	cleavage furrow	50	2.098747e-41	7.253269632e-40	2.137755	395	0.008991987	139	0.00676757027913669	1.215239	50	52	0.003365417	
GO Cellular Component	mitochondrial ribosome	86	5.703106e-27	1.1459264148837207e-25	2.034762	283	0.00644236	134	0.005762655617910448	1.174636	79	85	0.005317359	
GO Cellular Component	nuclear ubiquitin ligase complex	89	1.792446e-26	3.480164817977528e-25	2.376103	196	0.004461847	214	0.045195468560747666	1.200656	38	40	0.002557717	
GO Cellular Component	mitochondrial large ribosomal subunit	114	2.77001e-21	4.198752e-20	2.201608	182	0.004143143	148	0.007751316454054055	1.214286	49	51	0.003298109	
GO Molecular Function	cyclin-dependent protein serine/threonine kinase regulator activity	67	4.354115e-21	2.743742317910448e-19	2.126696	195	0.004439082	138	0.034198047028985504	1.263849	29	29	0.001951942	
Human Phenotype	Abnormality of transition element cation homeostasis	117	1.270614e-19	7.246843779487179e-18	2.557952	123	0.002800036	306	0.024375967434640523	1.263849	29	29	0.001951942	
Mouse Phenotype	extramedullary hematopoiesis	18	9.489598e-120	5.040558137666667e-117	2.009225	1355	0.03084593	597	0.005431721010050252	1.126631	156	175	0.0105001	
Mouse Phenotype	increased liver adenoma incidence	553	5.995324e-20	1.0365514062206148e-18	2.193359	171	0.003892734	754	0.01792091522546419	1.263849	28	28	0.001884634