# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	cytoplasmic sequestering of protein	87	3.092921e-41	4.67813188954023e-39	3.079022	200	0.004819626	1006	0.00995628383528827	1.24799	38	39	0.002592087	
GO Biological Process	maintenance of protein localization in organelle	149	4.134147e-29	3.651089957919463e-27	2.737765	167	0.004024387	1363	0.04337833938517975	1.239515	30	31	0.002046385	
GO Biological Process	gene silencing by miRNA	164	1.138275e-27	9.133268734756098e-26	2.087791	273	0.006578789	655	0.0003691201959389313	1.280832	44	44	0.003001364	
GO Biological Process	IRE1-mediated unfolded protein response	170	2.768566e-27	2.1430329408235298e-25	2.135282	255	0.006145023	763	0.0014577729910353865	1.236666	56	58	0.003819918	
GO Biological Process	negative regulation of Notch signaling pathway	184	6.889096e-26	4.9268268621739126e-24	2.113238	247	0.005952238	1262	0.030185995248811413	1.242019	32	33	0.00218281	
GO Biological Process	response to arsenic-containing substance	381	5.005087e-17	1.728659838136483e-15	2.018517	175	0.004217172	1000	0.009984075434000001	1.280832	29	29	0.001978172	
GO Biological Process	histone H2A ubiquitination	492	2.078581e-14	5.559359223373983e-13	2.008369	147	0.003542425	1342	0.04218319443591654	1.280832	22	22	0.001500682	
GO Biological Process	positive regulation of transcription from RNA polymerase I promoter	847	4.281059e-10	6.651057305903189e-9	2.003042	98	0.002361617	1342	0.04218319443591654	1.280832	22	22	0.001500682	
GO Cellular Component	PcG protein complex	40	9.129554e-35	3.943967328e-33	2.069927	355	0.008554835	123	0.00015713055219512197	1.280832	46	46	0.00313779	
GO Cellular Component	cytoplasmic stress granule	51	8.901117e-25	3.0159078776470587e-23	2.011342	266	0.006410102	229	0.01505307584279476	1.221259	41	43	0.002796726	
GO Cellular Component	nuclear ubiquitin ligase complex	61	1.143785e-20	3.240099147540983e-19	2.220138	173	0.004168976	251	0.025284701832669326	1.216791	38	40	0.002592087	
GO Cellular Component	INO80-type complex	212	3.238555e-8	2.639727849056604e-7	2.074284	70	0.001686869	246	0.023585352585365857	1.280832	23	23	0.001568895	
GO Molecular Function	NF-kappaB binding	66	4.248143e-16	2.7175242039393942e-14	2.077888	153	0.003687014	156	0.02631195055769231	1.280832	28	28	0.001909959	
Human Phenotype	Abnormality of subcutaneous fat tissue	70	4.301555e-18	4.1006109307142856e-16	2.159984	159	0.003831602	529	0.020135115245746696	1.280832	26	26	0.001773533	
Mouse Phenotype Single KO	abnormal interventricular septum thickness	11	2.170194e-39	1.8065878598181817e-36	2.217667	345	0.008313854	346	0.000623211658034682	1.280832	43	43	0.002933151	
Mouse Phenotype Single KO	thoracic vertebral transformation	19	8.395627e-33	4.0462503388947366e-30	2.188957	293	0.007060751	412	0.0021976224353640775	1.254148	47	48	0.003206003	
Mouse Phenotype Single KO	increased hemangiosarcoma incidence	151	1.141149e-16	6.920199598013244e-15	2.047068	165	0.003976191	702	0.03418283316096866	1.280832	24	24	0.001637108	
Mouse Phenotype	thoracic vertebral transformation	27	6.3967e-38	2.2651425444444446e-35	2.178435	345	0.008313854	579	0.0017311734461139896	1.235891	55	57	0.003751705	
Mouse Phenotype	increased incidence of corneal inflammation	201	2.968149e-17	1.4118643079104475e-15	2.165398	150	0.003614719	1167	0.0451575451722365	1.280832	21	21	0.001432469	
Mouse Phenotype	increased embryonic neuroepithelium apoptosis	203	3.785828e-17	1.7830690398029557e-15	2.068368	166	0.004000289	963	0.02030582653894081	1.280832	25	25	0.001705321