# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	beta-catenin-TCF complex assembly	103	4.120327e-42	5.264017766310679e-40	2.578092	273	0.01204341	520	0.007600656114038462	1.383148	38	43	0.003167459	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	163	9.349837e-32	7.54812914619632e-30	2.098363	311	0.01371978	810	0.046628786534567895	1.215482	73	94	0.006084855	
GO Biological Process	regulation of mitochondrial membrane permeability	167	1.716184e-31	1.3522913326946108e-29	2.205627	275	0.01213164	824	0.04783119236771845	1.243537	58	73	0.004834542	
GO Biological Process	regulation of response to reactive oxygen species	392	3.387746e-19	1.1372283064795917e-17	2.07101	187	0.008249515	697	0.027331639469153513	1.381007	30	34	0.002500625	
GO Biological Process	cell differentiation involved in embryonic placenta development	431	1.16414e-17	3.554273378190256e-16	2.069051	171	0.007543674	309	0.00023535591199352752	1.565141	27	27	0.002250563	
GO Biological Process	regulation of hydrogen peroxide-induced cell death	432	1.184669e-17	3.608578558101852e-16	2.228715	144	0.006352567	558	0.010999188332616488	1.497092	22	23	0.001833792	
GO Biological Process	labyrinthine layer morphogenesis	478	3.827301e-16	1.0536287418200837e-14	2.026208	163	0.007190753	431	0.00249099931062645	1.565141	21	21	0.001750438	
GO Biological Process	regulation of transcription elongation from RNA polymerase II promoter	754	1.206544e-10	2.1056913124668435e-9	2.310473	75	0.003308629	643	0.021247589673405908	1.444746	24	26	0.0020005	
GO Biological Process	DNA catabolic process	895	2.564554e-9	3.770610735865921e-8	2.161538	74	0.003264514	600	0.015618592553333333	1.449205	25	27	0.002083854	
GO Biological Process	regulation of receptor biosynthetic process	1021	2.047328e-8	2.638666910088149e-7	2.302067	57	0.002514558	713	0.029054536781206168	1.486884	19	20	0.001583729	
GO Biological Process	mismatch repair	1023	2.23754e-8	2.8781807292277616e-7	2.094197	70	0.003088054	787	0.04324269782083863	1.397448	25	28	0.002083854	
GO Cellular Component	cytoplasmic stress granule	83	1.702605e-15	3.544700530120482e-14	2.0625	149	0.006573143	135	0.047154560000000005	1.310351	36	43	0.00300075	
GO Molecular Function	protein phosphatase 2A binding	64	3.485562e-14	2.299381681875e-12	2.087515	131	0.005779072	106	0.02836498920754717	1.449205	25	27	0.002083854	
Mouse Phenotype Single KO	increased B cell derived lymphoma incidence	45	3.184372e-37	6.479843200888889e-35	2.578137	240	0.01058761	582	0.04145539103608247	1.304284	40	48	0.003334167	
Mouse Phenotype Single KO	abnormal Paneth cell morphology	84	2.297039e-29	2.5040459670238096e-27	2.937981	150	0.006617258	528	0.03267228005681818	1.565141	14	14	0.001166958	
Mouse Phenotype Single KO	abnormal cellular replicative senescence	206	7.526104e-17	3.3454628314563106e-15	2.021294	172	0.007587789	549	0.035516500322404373	1.278199	49	60	0.004084354	
Mouse Phenotype Single KO	increased lung adenoma incidence	313	4.371329e-13	1.2788581358785943e-11	2.129688	114	0.005029116	435	0.019024372694252875	1.413676	28	31	0.002333917	
Mouse Phenotype Single KO	abnormal parietal endoderm morphology	435	2.478452e-10	5.217283899770115e-9	2.007848	100	0.004411505	619	0.046797580764135704	1.429042	21	23	0.001750438	
Mouse Phenotype Single KO	increased incidence of tumors by ionizing radiation induction	655	1.378361e-7	0.0000019269697216793896	2.457609	44	0.001941062	471	0.02339137180467091	1.565141	15	15	0.001250313	
Mouse Phenotype	abnormal pancreatic duct morphology	105	1.041873e-33	9.48699786e-32	2.593192	214	0.009440621	627	0.007112261688038277	1.497092	22	23	0.001833792	
Mouse Phenotype	abnormal Paneth cell morphology	119	8.042289e-31	6.461539926806723e-29	2.276626	251	0.01107288	1055	0.046668917573459714	1.318014	32	38	0.002667334	
Mouse Phenotype	increased B cell derived lymphoma incidence	128	1.879283e-29	1.403736309609375e-27	2.046933	305	0.01345509	594	0.005730369254040404	1.284218	64	78	0.005334667	
Mouse Phenotype	increased skin papilloma incidence	342	2.039691e-15	5.702188786842105e-14	2.005023	159	0.007014293	1035	0.045137702704347825	1.304284	35	42	0.002917396	
Mouse Phenotype	lethality during fetal growth through weaning, incomplete penetrance	347	3.183817e-15	8.772470990489913e-14	2.827162	78	0.003440974	1060	0.047004789399056605	1.473074	16	17	0.001333667	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	374	1.650505e-14	4.2193792259358284e-13	2.440091	96	0.004235045	768	0.01602399946484375	1.408627	27	30	0.002250563	
Mouse Phenotype	abnormal epidermis suprabasal layer morphology	379	1.989396e-14	5.018631967282322e-13	2.071835	136	0.005999647	958	0.036397479479123175	1.391237	24	27	0.0020005	
Mouse Phenotype	increased adrenal gland tumor incidence	638	8.75871e-10	1.3125709452978057e-8	2.479332	59	0.002602788	1060	0.047004789399056605	1.473074	16	17	0.001333667	
Mouse Phenotype	absent embryonic cilia	714	7.268539e-9	9.733123442436974e-8	2.515433	51	0.002249868	951	0.03524279104100946	1.478189	17	18	0.001417021	
Mouse Phenotype	increased incidence of tumors by ionizing radiation induction	1024	0.00000192996	0.0000180198706640625	2.098096	50	0.002205753	872	0.02578762877408257	1.482765	18	19	0.001500375