# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	26	1.647315e-31	8.337314648076924e-29	2.849345	169	0.01549748	278	0.0000010400040512230216	1.550479	84	118	0.009743649	
GO Biological Process	nuclear-transcribed mRNA catabolic process	39	2.000145e-26	6.748694373076924e-24	2.109072	251	0.02301696	240	1.4582233576666666e-7	1.452036	132	198	0.01531145	
GO Biological Process	mRNA catabolic process	43	2.470968e-25	7.561736723720931e-23	2.021146	266	0.02439248	194	7.569653703092783e-9	1.472487	144	213	0.0167034	
GO Biological Process	viral gene expression	68	1.644375e-20	3.1821074448529416e-18	2.336243	153	0.01403026	358	0.0000198698143226257	1.474902	86	127	0.009975641	
GO Biological Process	multi-organism metabolic process	77	1.913246e-18	3.2696628719480514e-16	2.071141	178	0.01632279	365	0.00002447541192630137	1.437219	97	147	0.01125159	
GO Biological Process	SRP-dependent cotranslational protein targeting to membrane	81	4.076617e-18	6.62274112382716e-16	2.511859	116	0.01063732	581	0.001401480156695353	1.444144	61	92	0.007075745	
GO Biological Process	viral transcription	82	4.29018e-18	6.884692514634146e-16	2.290518	139	0.01274645	394	0.000047838041568527915	1.48416	77	113	0.008931678	
GO Biological Process	protein targeting to ER	83	5.436065e-18	8.618455341566264e-16	2.406101	125	0.01146263	582	0.0014136313503608248	1.423283	66	101	0.007655724	
GO Biological Process	cotranslational protein targeting to membrane	88	1.089801e-17	1.6296240180681817e-15	2.433614	120	0.01100413	503	0.00037969051850894636	1.466852	66	98	0.007655724	
GO Biological Process	protein localization to endoplasmic reticulum	98	1.147676e-16	1.5410478044897958e-14	2.117876	151	0.01384686	446	0.00012525187618609866	1.440326	82	124	0.009511658	
GO Biological Process	multi-organism transport	112	3.49084e-15	4.101425317857143e-13	2.366861	107	0.009812013	588	0.0015460945495408163	1.503164	49	71	0.005683795	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	113	4.236382e-15	4.933323074159292e-13	2.018554	152	0.01393856	519	0.0005220575901541425	1.426336	74	113	0.008583691	
GO Biological Process	establishment of protein localization to endoplasmic reticulum	121	1.278325e-14	1.3902048491735537e-12	2.142713	127	0.01164603	593	0.001649210812833052	1.410549	68	105	0.007887716	
GO Biological Process	transport of virus	125	4.18936e-14	4.4102230592e-12	2.326411	102	0.009353508	563	0.0011855298369626997	1.527888	47	67	0.005451804	
GO Biological Process	regulation of viral transcription	129	1.065929e-13	1.0873302101550387e-11	2.289736	102	0.009353508	1118	0.0463651362236136	1.373849	41	65	0.004755829	
GO Biological Process	negative regulation of ubiquitin-protein transferase activity	135	2.301692e-13	2.2435529650370372e-11	2.191917	109	0.009995415	678	0.004478727757374631	1.426107	55	84	0.00637977	
GO Biological Process	base-excision repair, AP site formation	145	1.048556e-12	9.515826485517242e-11	7.489779	22	0.002017423	732	0.007461041543989071	2.178054	10	10	0.001159958	
GO Biological Process	multi-organism intracellular transport	148	1.239577e-12	1.1021347123648648e-10	2.266951	95	0.0087116	624	0.0025439257163461537	1.507883	45	65	0.005219812	
GO Biological Process	intracellular transport of virus	156	2.316425e-12	1.9539638830128206e-10	2.26308	93	0.008528198	654	0.003708938596941896	1.497412	44	64	0.005103816	
GO Biological Process	snRNA metabolic process	170	7.459007e-12	5.773710183117647e-10	2.171713	97	0.008895002	511	0.0004436434530528376	1.494246	59	86	0.006843754	
GO Cellular Component	ribosomal subunit	32	7.732119e-20	4.17534426e-18	2.056705	196	0.01797341	87	0.00011654474151724138	1.353925	115	185	0.01333952	
GO Cellular Component	methyltransferase complex	45	4.163206e-13	1.5986711039999998e-11	2.028424	128	0.01173773	147	0.0053554458122448976	1.38821	58	91	0.006727758	
GO Cellular Component	histone methyltransferase complex	50	2.405644e-12	8.313905664e-11	2.083067	112	0.01027052	94	0.00038305017191489363	1.546734	49	69	0.005683795	
GO Cellular Component	large ribosomal subunit	51	6.787943e-12	2.2999148047058822e-10	2.018096	116	0.01063732	132	0.002931646254545455	1.363651	72	115	0.008351699	
GO Cellular Component	mitochondrial ribosome	70	1.581706e-9	3.9045542400000004e-8	2.172222	75	0.006877579	200	0.02825158176	1.332456	52	85	0.006031783	
GO Cellular Component	spliceosomal snRNP complex	99	1.810288e-7	0.0000031597754181818184	2.060589	63	0.005777166	143	0.00510079257062937	1.475456	42	62	0.004871825	
GO Cellular Component	proteasome regulatory particle, lid subcomplex	103	3.47986e-7	0.0000058380563883495136	5.271182	15	0.001375516	211	0.03517296500473934	2.178054	7	7	0.0008119708	
GO Cellular Component	axon cytoplasm	110	5.420107e-7	0.00000851449536	2.005555	62	0.005685465	152	0.006720236336842106	1.579089	29	40	0.003363879	
GO Cellular Component	mitochondrial nucleoid	114	6.870165e-7	0.000010413723789473685	2.158229	51	0.004676754	218	0.04247087119266055	1.452036	28	42	0.003247883	
GO Cellular Component	nuclear transcriptional repressor complex	127	0.00000152429	0.000020739945826771656	2.033228	55	0.005043558	163	0.01074679244171779	1.652317	22	29	0.002551908	
GO Cellular Component	INO80-type complex	134	0.000002241753	0.000028908576	2.931802	26	0.002384227	136	0.004299122964705882	1.799262	19	23	0.002203921	
GO Cellular Component	Cul4-RING E3 ubiquitin ligase complex	144	0.000005548671	0.00006658405200000001	2.1458	43	0.003943145	191	0.023909367958115185	1.565476	23	32	0.002667904	
GO Cellular Component	MLL1 complex	156	0.0000110124	0.0001219835076923077	2.254829	36	0.003301238	205	0.029505743297560977	1.577211	21	29	0.002435912	
GO Cellular Component	cytoplasmic exosome (RNase complex)	157	0.00001127333	0.00012407843464968155	3.940268	15	0.001375516	215	0.04022760692093023	1.842968	11	13	0.001275954	
GO Cellular Component	ESCRT complex	167	0.00002169715	0.0002245070371257485	2.270782	33	0.003026135	175	0.016783382674285717	1.63354	21	28	0.002435912	
GO Cellular Component	exosome (RNase complex)	196	0.0001198416	0.0010565626775510203	2.225685	28	0.00256763	136	0.004299122964705882	1.799262	19	23	0.002203921	
GO Cellular Component	telomerase holoenzyme complex	199	0.0001307043	0.001134959951758794	2.336476	25	0.002292526	192	0.025086069000000003	1.683041	17	22	0.001971929	
GO Cellular Component	Swr1 complex	248	0.0008902593	0.006203097058064516	3.196197	11	0.001008712	160	0.009768442320000001	2.178054	9	9	0.001043962	
GO Molecular Function	DNA N-glycosylase activity	35	1.974472e-9	2.3817773668571425e-7	4.403741	25	0.002292526	124	0.010968098866129032	2.022478	13	14	0.001507946	
GO Molecular Function	NF-kappaB binding	73	4.352731e-7	0.000025174288057534246	2.325596	45	0.004126547	129	0.01415362006356589	1.711328	22	28	0.002551908	
GO Molecular Function	K63-linked polyubiquitin binding	130	0.00003685283	0.0011968665250769233	2.150958	35	0.003209537	115	0.00722379060173913	1.866903	18	21	0.002087925	
GO Molecular Function	cyclin-dependent protein serine/threonine kinase inhibitor activity	148	0.00007704894	0.0021979771937837836	2.827331	19	0.00174232	158	0.03538233739240506	1.996549	11	12	0.001275954	
Human Phenotype	Trigonocephaly	16	2.497171e-9	0.0000010414763801875	2.545141	53	0.004860156	192	0.04459784857812501	1.815045	15	18	0.001739937	
Human Phenotype	Heterotopia	25	4.924738e-8	0.0000131451106696	2.362115	51	0.004676754	81	0.004081222452716049	1.960248	18	20	0.002087925	
Mouse Phenotype	enlarged liver sinusoidal spaces	15	1.285031e-11	8.190787594000001e-9	2.159369	96	0.008803301	548	0.019813898863138685	1.540574	29	41	0.003363879	
Mouse Phenotype	increased sensitivity to skin irradiation	20	5.820557e-11	2.78251727385e-8	5.75301	23	0.002109124	671	0.03791723038301043	1.980049	10	11	0.001159958	
Mouse Phenotype	tumor regression	62	6.594012e-8	0.000010168604634193548	4.930108	18	0.001650619	611	0.03084254979869067	2.178054	8	8	0.0009279666	
Mouse Phenotype	decreased mortality induced by ionizing radiation	439	0.001549185	0.03373976716400911	2.568334	14	0.001283815	611	0.03084254979869067	2.178054	8	8	0.0009279666