# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	regulation of gene expression, epigenetic	13	1.483875e-38	1.5020239326923078e-35	2.271718	315	0.0347951	191	0.00000900103847068063	1.399368	142	248	0.01848236	
GO Biological Process	response to topologically incorrect protein	27	1.61389e-27	7.8656216703703705e-25	2.265038	223	0.02463272	194	0.000011429419024742267	1.46638	108	180	0.01405701	
GO Biological Process	nucleosome organization	30	9.827275e-26	4.310570390833333e-23	2.238509	213	0.02352811	187	0.0000076471874828877	1.486389	104	171	0.01353638	
GO Biological Process	macromolecular complex disassembly	33	9.557793e-24	3.811242366272727e-21	2.102775	225	0.02485364	142	1.6234388036619717e-7	1.522681	119	191	0.01548874	
GO Biological Process	chromatin assembly or disassembly	35	1.399193e-23	5.260565910571429e-21	2.133222	216	0.02385949	209	0.000023270438561722487	1.455396	106	178	0.01379669	
GO Biological Process	cellular response to topologically incorrect protein	44	2.044935e-22	6.115749923863636e-20	2.316836	171	0.01888877	250	0.000133484001188	1.47693	84	139	0.01093323	
GO Biological Process	regulation of hematopoietic progenitor cell differentiation	51	1.672199e-21	4.3146013021568623e-19	2.612637	130	0.01435988	626	0.03891187770607029	1.340938	62	113	0.008069764	
GO Biological Process	chromatin assembly	57	1.022498e-20	2.36053529508772e-18	2.123339	190	0.02098752	308	0.0006881593042857142	1.407601	91	158	0.01184433	
GO Biological Process	multi-organism metabolic process	62	3.835356e-20	8.140233807096775e-18	2.25657	161	0.01778416	169	0.000002699795433964497	1.546183	93	147	0.01210465	
GO Biological Process	gene silencing	64	1.295568e-19	2.6638092675000002e-17	2.079919	188	0.0207666	384	0.0030466830517447917	1.344182	99	180	0.01288559	
GO Biological Process	nucleosome assembly	68	1.892396e-19	3.6620645535294114e-17	2.152338	172	0.01899923	365	0.0026241281227397262	1.394094	81	142	0.01054276	
GO Biological Process	response to unfolded protein	70	2.303151e-19	4.329594858428572e-17	2.067895	188	0.0207666	264	0.00018669047135227271	1.435831	94	160	0.0122348	
GO Biological Process	regulation of transcription from RNA polymerase II promoter in response to stress	79	1.841698e-17	3.0677093648101267e-15	2.239535	140	0.01546449	399	0.004173991926065163	1.42745	66	113	0.008590394	
GO Biological Process	regulation of DNA-templated transcription in response to stress	81	2.530716e-17	4.11131998074074e-15	2.149542	152	0.01679001	321	0.0011115095747352025	1.458165	71	119	0.009241182	
GO Biological Process	regulation of gene silencing	99	1.049222e-15	1.3946174038383837e-13	2.070037	149	0.01645863	474	0.011733658207172995	1.361905	73	131	0.009501497	
GO Biological Process	translational elongation	100	1.235229e-15	1.6254378410999998e-13	2.329954	114	0.01259251	422	0.005720170526303317	1.418374	65	112	0.008460237	
GO Biological Process	endoplasmic reticulum unfolded protein response	102	1.31284e-15	1.6936923098039218e-13	2.18898	130	0.01435988	378	0.0030221091686243387	1.436367	67	114	0.008720552	
GO Biological Process	viral gene expression	104	1.763682e-15	2.2315664844230767e-13	2.243983	122	0.0134762	245	0.00012729925292653062	1.501019	78	127	0.01015228	
GO Biological Process	regulation of cellular response to heat	105	1.794081e-15	2.248410655142857e-13	2.252041	121	0.01336574	292	0.00048548868678082195	1.597979	51	78	0.006638032	
GO Biological Process	regulation of membrane permeability	108	2.52054e-15	3.0710912833333334e-13	2.207654	125	0.01380758	449	0.008440226561024498	1.478449	49	81	0.006377717	
GO Cellular Component	ribosomal subunit	36	3.626437e-18	1.74068976e-16	2.11089	167	0.01844692	71	0.00022321162546478873	1.387117	105	185	0.01366654	
GO Cellular Component	ficolin-1-rich granule lumen	37	4.771475e-17	2.228407783783784e-15	2.19831	142	0.01568541	134	0.027058855164179104	1.320531	67	124	0.008720552	
GO Cellular Component	methyltransferase complex	40	7.310056e-16	3.157944192e-14	2.290673	120	0.01325527	50	4.2683016959999997e-7	1.718834	64	91	0.008330079	
GO Cellular Component	histone methyltransferase complex	47	2.101939e-14	7.727979982978724e-13	2.329978	104	0.0114879	53	0.0000034284139471698114	1.770991	50	69	0.006507875	
GO Cellular Component	host cell	55	2.995718e-13	9.41200128e-12	2.388697	90	0.009941456	67	0.0001918325014925373	1.653272	46	68	0.005987245	
GO Cellular Component	other organism cell	61	1.94094e-12	5.49826937704918e-11	2.281195	92	0.01016238	79	0.0005831234430379747	1.585276	48	74	0.00624756	
GO Cellular Component	small ribosomal subunit	73	7.217102e-11	1.708377021369863e-9	2.334664	75	0.008284547	98	0.0030798866938775513	1.52748	45	72	0.005857087	
GO Cellular Component	BLOC complex	77	9.115993e-10	2.0457708966233766e-8	3.301427	37	0.004087043	124	0.019218788129032258	1.806411	17	23	0.002212677	
GO Cellular Component	cytoplasmic stress granule	128	0.000001131866	0.000015280191000000002	2.010279	58	0.006406716	146	0.0364541957260274	1.534584	27	43	0.003514252	
GO Cellular Component	spliceosomal snRNP complex	142	0.000004841934	0.000058921563042253514	2.009344	51	0.005633492	96	0.0026402723999999996	1.576753	40	62	0.0052063	
GO Cellular Component	MLL1 complex	161	0.00002191145	0.00023517382360248445	2.338869	31	0.003424279	80	0.0006125742720000001	1.938319	23	29	0.002993622	
GO Cellular Component	precatalytic spliceosome	225	0.000400352	0.0030747033599999997	2.247722	23	0.002540594	149	0.04181581401342282	1.658406	19	28	0.002472992	
GO Cellular Component	MLL3/4 complex	346	0.006927989	0.034599898820809244	2.038574	16	0.00176737	156	0.04974766892307693	2.172415	8	9	0.00104126	
GO Molecular Function	ribonucleoprotein complex binding	13	2.30051e-17	7.471348630769231e-15	2.287662	133	0.01469126	53	0.0004039995156226416	1.508884	71	115	0.009241182	
GO Molecular Function	snRNA binding	33	2.793091e-9	3.5734636975757575e-7	3.050995	39	0.004307964	78	0.008842816615384615	1.736503	27	38	0.003514252	
GO Molecular Function	histone methyltransferase activity (H3-K4 specific)	69	0.000001458629	0.00008925118315942029	3.003354	26	0.002871976	102	0.024509078390196077	2.012679	14	17	0.001822205	
GO Molecular Function	ribosomal small subunit binding	80	0.000003911653	0.00020643748707499998	2.714647	28	0.003092897	107	0.03056703536074766	2.094829	12	14	0.00156189	
GO Molecular Function	SUMO transferase activity	98	0.00001358574	0.00058529586	2.532144	28	0.003092897	76	0.0077031001078947375	2.058078	16	19	0.00208252	
GO Molecular Function	microtubule plus-end binding	273	0.001075451	0.01663206638095238	2.124643	22	0.002430134	92	0.0184533065	2.240303	11	12	0.001431732	
Human Phenotype	Abnormal concentration of calcium in blood	24	5.949256e-13	1.6541410536666666e-10	2.722644	69	0.007621783	108	0.03765399660555556	1.649678	27	40	0.003514252	
Human Phenotype	Abnormality of divalent inorganic cation homeostasis	28	6.737972e-12	1.6058031127142856e-9	2.382136	80	0.00883685	124	0.04922052156774193	1.516945	36	58	0.00468567	
Human Phenotype	Basal cell carcinoma	147	0.00004700764	0.0021338910321088435	2.277613	30	0.003313819	72	0.0098365858875	1.99961	18	22	0.002342835	
Mouse Phenotype Single KO	increased integument system tumor incidence	32	1.444204e-12	4.1326800087499997e-10	2.216749	99	0.0109356	131	0.005132146200152672	1.543558	48	76	0.00624756	
Mouse Phenotype Single KO	abnormal DNA repair	58	4.904957e-10	7.743912284310344e-8	2.026532	94	0.0103833	150	0.00797528915	1.471636	56	93	0.007288819	
Mouse Phenotype	abnormal DNA repair	6	4.830296e-20	7.697076676e-17	2.384271	143	0.01579587	71	0.000030635975645070424	1.562536	78	122	0.01015228	
Mouse Phenotype	early cellular replicative senescence	25	1.388825e-14	5.311422329999999e-12	2.324201	106	0.01170883	179	0.005968633184916201	1.540034	46	73	0.005987245	
Mouse Phenotype	abnormal cellular replicative senescence	33	3.992281e-13	1.1566726860909092e-10	2.153414	111	0.01226113	193	0.009511644433678756	1.483837	51	84	0.006638032	
Mouse Phenotype	increased cellular sensitivity to ultraviolet irradiation	132	2.02548e-7	0.000014670919909090908	2.545749	40	0.004418425	287	0.040167126857142854	1.710777	21	30	0.002733307