# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	small molecule catabolic process	1	1.284694e-9	0.000016905288346000002	3.613788	31	0.08933718	1	0.000073055372978	3.405991	30	346	0.06276151	
GO Biological Process	carboxylic acid catabolic process	2	1.564672e-8	0.00010294759424000001	3.999389	24	0.06916427	2	0.000101151061765	4.033463	23	224	0.04811715	
GO Biological Process	branched-chain amino acid catabolic process	3	2.071171e-8	0.00009084846396333334	14.41586	9	0.0259366	3	0.00011097568082333334	14.96473	8	21	0.0167364	
GO Biological Process	branched-chain amino acid metabolic process	4	9.788784e-8	0.00032202652164	11.98275	9	0.0259366	4	0.00028124480679000003	13.09414	8	24	0.0167364	
GO Biological Process	carboxylic acid metabolic process	5	3.778943e-7	0.0009945422187399998	2.182773	48	0.1383285	6	0.0007338932207999999	2.205823	47	837	0.09832636	
GO Biological Process	cellular amino acid catabolic process	6	3.834862e-7	0.0008410491509666666	4.80955	16	0.04610951	5	0.00047565389894000006	5.214481	15	113	0.03138075	
GO Biological Process	cofactor metabolic process	7	0.000006411503	0.012052709711	2.765997	25	0.07204611	14	0.014091578330000002	2.655713	24	355	0.05020921	
GO Biological Process	cellular amino acid metabolic process	12	0.00004101155	0.04497258220416667	2.590746	23	0.06628242	15	0.02300212499866667	2.700667	22	320	0.0460251	
GO Cellular Component	mitochondrial matrix	1	2.686954e-10	4.643056512e-7	3.568739	34	0.09798271	1	0.0012049236864	2.68228	31	454	0.06485356	
GO Cellular Component	mitochondrial part	2	2.911855e-8	0.0000251584272	2.280387	52	0.1498559	3	0.00974514816	1.877892	49	1025	0.1025105	
GO Cellular Component	Seh1-associated complex	5	0.00001501119	0.005187867264	16.75384	5	0.01440922	4	0.01099621008	13.09414	5	15	0.01046025	
GO Cellular Component	GATOR2 complex	6	0.0001228321	0.0353756448	16.28498	4	0.01152738	12	0.0170952768	14.28452	4	11	0.008368201	
Human Phenotype	Abnormality of the urinary system physiology	1	0.000001851344	0.012354018512	2.643248	30	0.08645533	2	0.0027557654925	2.771753	29	411	0.06066946	
Human Phenotype	Abnormality of urine homeostasis	2	0.000002176879	0.0072631567835	3.03007	24	0.06916427	7	0.0020734631585714288	3.062698	23	295	0.04811715	
Human Phenotype	Pancreatitis	3	0.000002941439	0.006542740815666667	9.431447	8	0.02305476	6	0.0023817382816666666	10.99908	7	25	0.01464435	
Human Phenotype	Abnormality of the abdominal organs	4	0.000004768683	0.00795535541475	2.428359	32	0.09221902	13	0.0033680288983846157	2.367303	32	531	0.06694561	
Human Phenotype	Abnormality of abdomen morphology	5	0.00000489065	0.006527061490000001	2.810576	25	0.07204611	3	0.002497227892666667	2.926485	26	349	0.05439331	
Human Phenotype	Visceromegaly	6	0.000005929169	0.006594224122833333	2.935086	23	0.06628242	8	0.00215623147575	2.946182	24	320	0.05020921	
Human Phenotype	Aciduria	8	0.000007793688	0.006500910003	4.009305	15	0.04322767	5	0.0018451819258	4.463912	15	132	0.03138075	
Human Phenotype	Delayed myelination	9	0.000009053113	0.006712380338777778	5.385909	11	0.03170029	15	0.004676078057999999	5.611775	10	70	0.0209205	
Human Phenotype	Hepatomegaly	10	0.000009577625	0.0063911491625	3.133651	20	0.05763689	11	0.0028268429519999996	3.112947	21	265	0.04393305	
Human Phenotype	Acidosis	11	0.00001062854	0.006447658856363636	3.110841	20	0.05763689	19	0.010351140039473685	2.938449	19	254	0.03974895	
Human Phenotype	Abnormality of blood glucose concentration	12	0.00001697869	0.009441566530833332	3.978269	14	0.04034582	10	0.0027035686192000002	4.364714	14	126	0.0292887	
Human Phenotype	Abnormality of carboxylic acid metabolism	13	0.00002620152	0.013449441766153848	3.271946	17	0.04899135	4	0.0020222426405000003	4.022899	17	166	0.03556485	
Human Phenotype	Abnormality of acid-base homeostasis	14	0.00002769338	0.013199851767142858	2.905587	20	0.05763689	26	0.018206803123846156	2.754118	19	271	0.03974895	
Human Phenotype	Hypoglycemia	15	0.00003139346	0.013965903905333334	4.313245	12	0.03458213	20	0.0103780264345	4.171585	12	113	0.0251046	
Human Phenotype	Lethargy	17	0.0000499334	0.019600328129411766	4.457451	11	0.03170029	14	0.004301993491142857	5.144127	11	84	0.02301255	
Human Phenotype	Abnormality of branched chain family amino acid metabolism	19	0.00006627171	0.02327532214894737	19.13837	4	0.01152738	17	0.010506210642941176	19.64121	4	8	0.008368201	
Human Phenotype	Abnormality of amino acid metabolism	20	0.00007780416	0.025959357984	3.270997	15	0.04322767	9	0.0021608093391111112	4.208831	15	140	0.03138075	
Human Phenotype	Abnormality of lipid metabolism	21	0.00007811724	0.02482268297714286	4.235934	11	0.03170029	34	0.048754547370588236	3.600889	11	120	0.02301255	
Human Phenotype	Abnormal glucose homeostasis	23	0.0001188658	0.03448658623478261	2.886228	17	0.04899135	25	0.0180815852028	2.968006	17	225	0.03556485	
Human Phenotype	Ketosis	24	0.000151282	0.04206269941666666	7.735438	6	0.01729107	23	0.017900818623043477	8.417663	6	28	0.0125523	
Mouse Phenotype Single KO	aciduria	1	0.000002327345	0.021311498164999998	7.036617	10	0.02881844	5	0.028691554844	6.983543	8	45	0.0167364