# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	cellular response to arsenic-containing substance	237	6.45955e-19	3.5865493016877635e-17	3.203111	82	0.003564907	815	0.012139277605276073	1.614948	15	15	0.001290101	
GO Biological Process	response to arsenic-containing substance	242	7.572109e-19	4.117412493016529e-17	2.517855	121	0.005260412	522	0.0004316134353831418	1.55926	28	29	0.002408188	
GO Biological Process	pyrimidine deoxyribonucleotide catabolic process	287	2.251797e-17	1.0324528474912891e-15	4.694208	47	0.002043301	1063	0.03925074690216369	1.614948	12	12	0.001032081	
GO Biological Process	pyrimidine nucleotide catabolic process	316	1.19823e-16	4.989717901898734e-15	4.399886	48	0.002086775	963	0.026817946347871234	1.614948	13	13	0.001118087	
GO Biological Process	positive regulation of mRNA catabolic process	547	2.439508e-12	5.868644565265082e-11	2.055594	116	0.00504304	1120	0.0485988188	1.421154	22	25	0.001892148	
GO Biological Process	positive regulation of mitochondrial membrane permeability	689	1.543428e-10	2.9477458711175614e-9	2.169208	85	0.003695331	844	0.014173577609478674	1.534201	19	20	0.001634127	
GO Biological Process	pyrimidine deoxyribonucleotide metabolic process	773	8.278588e-10	1.409287703648124e-8	2.363212	65	0.002825841	989	0.028658372722952477	1.525229	17	18	0.001462114	
GO Biological Process	mitochondrial outer membrane permeabilization involved in programmed cell death	778	9.052813e-10	1.5311820856940874e-8	2.165522	78	0.003391009	989	0.028658372722952477	1.525229	17	18	0.001462114	
GO Biological Process	mitochondrion transport along microtubule	779	9.13651e-10	1.543354750834403e-8	2.190128	76	0.003304061	989	0.028658372722952477	1.525229	17	18	0.001462114	
GO Biological Process	positive regulation of membrane permeability	805	1.485565e-9	2.4283912838509317e-8	2.05463	86	0.003738805	1021	0.03442652166895201	1.468135	20	22	0.001720134	
GO Biological Process	regulation of Rac protein signal transduction	993	2.847441e-8	3.773361139879154e-7	2.012683	76	0.003304061	883	0.018102879517553797	1.614948	14	14	0.001204094	
GO Cellular Component	cytoplasmic stress granule	58	9.795475e-21	2.918376e-19	2.264454	166	0.007216764	91	0.00221221978021978	1.427163	38	43	0.003268255	
Human Phenotype	Trigonocephaly	16	6.356625e-21	2.6511099140625e-18	2.709212	119	0.005173463	342	0.04202618327777778	1.525229	17	18	0.001462114	
Human Phenotype	Abnormality of subcutaneous fat tissue	162	7.294465e-13	3.0046891941358024e-11	2.303735	94	0.004086601	243	0.014771273163374486	1.490721	24	26	0.002064161	
Human Phenotype	Aplasia/hypoplasia of the femur	182	3.313308e-12	1.2148189167032966e-10	2.0597	114	0.004956091	277	0.023705998722743683	1.419197	29	33	0.002494195	
Human Phenotype	Distal upper limb amyotrophy	344	3.544001e-9	6.874743800290698e-8	3.195718	36	0.001565081	328	0.039927875155487805	1.614948	13	13	0.001118087	
Human Phenotype	Lipomatous tumor	612	0.000001734644	0.000018913855248366014	2.228669	44	0.001912877	296	0.027385135331081084	1.614948	14	14	0.001204094	
Mouse Phenotype Single KO	abnormal interventricular septum thickness	31	6.115814e-27	1.8065325418709677e-24	2.354097	203	0.00882532	758	0.020185277647757256	1.352049	36	43	0.003096242	
Mouse Phenotype Single KO	increased mammary adenocarcinoma incidence	144	8.023756e-15	5.102328728611111e-13	3.056398	67	0.00291279	850	0.02877599100235294	1.468135	20	22	0.001720134	
Mouse Phenotype Single KO	short premaxilla	166	5.768191e-14	3.1818870474096385e-12	2.143046	121	0.005260412	780	0.023040268152564103	1.614948	13	13	0.001118087	
Mouse Phenotype Single KO	abnormal white fat cell number	265	2.861696e-11	9.888509536603774e-10	2.119691	97	0.004217025	807	0.024440191857496907	1.525229	17	18	0.001462114	
Mouse Phenotype Single KO	multiple persisting craniopharyngeal ducts	404	4.041742e-9	9.16094838960396e-8	2.101488	77	0.003347535	632	0.010893406267246835	1.614948	15	15	0.001290101	
Mouse Phenotype Single KO	increased incidence of corneal inflammation	411	5.825795e-9	1.2979757862530414e-7	2.212569	67	0.00291279	979	0.04723140380286006	1.514014	15	16	0.001290101	
Mouse Phenotype Single KO	decreased white fat cell number	684	0.000001295341	0.000017341282948830407	2.147822	49	0.00213025	887	0.03273315728410372	1.614948	12	12	0.001032081	
Mouse Phenotype	abnormal stapedial artery morphology	66	1.899904e-26	2.7522700218181822e-24	3.077236	125	0.00543431	1437	0.0387767945427975	1.453453	18	20	0.001548121	
Mouse Phenotype	increased kidney tumor incidence	175	3.19453e-16	1.7453086474285716e-14	3.087693	73	0.003173637	1388	0.034783572391210375	1.514014	15	16	0.001290101	
Mouse Phenotype	short premaxilla	221	1.124267e-14	4.863853749773756e-13	2.034489	145	0.0063038	1093	0.012254997634034766	1.529951	18	19	0.001548121	
Mouse Phenotype	decreased liver function	326	5.953319e-12	1.7460025447546013e-10	2.928139	56	0.002434571	1400	0.03498233314285715	1.614948	11	11	0.0009460738	
Mouse Phenotype	liver failure	510	1.54745e-9	2.901013617647059e-8	2.507986	56	0.002434571	1501	0.04901764182211859	1.507285	14	15	0.001204094	
Mouse Phenotype	multiple persisting craniopharyngeal ducts	551	4.041742e-9	7.013265927767697e-8	2.101488	77	0.003347535	973	0.00738784955364851	1.614948	15	15	0.001290101	
Mouse Phenotype	absent vas deferens	634	2.94591e-8	4.442562383280757e-7	2.032339	74	0.003217112	1267	0.023926821312549328	1.614948	12	12	0.001032081	
Mouse Phenotype	absent metanephros	652	4.128265e-8	6.053733384202455e-7	2.084817	68	0.002956265	1267	0.023926821312549328	1.614948	12	12	0.001032081