# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	cellular response to epidermal growth factor stimulus	20	1.338462e-26	8.806410729e-24	3.512028	104	0.01530312	188	0.00037901335740425537	2.277541	24	38	0.00460918	
GO Biological Process	response to epidermal growth factor	24	3.339713e-25	1.8311368069583334e-22	3.316994	106	0.01559741	218	0.0009425586467889908	2.146492	25	42	0.004801229	
GO Biological Process	mRNA catabolic process	27	1.883283e-24	9.178563332222222e-22	2.304359	189	0.02781048	372	0.01408598080268817	1.388267	82	213	0.01574803	
GO Biological Process	nuclear-transcribed mRNA catabolic process	32	4.925484e-23	2.025451373625e-20	2.332578	173	0.02545615	407	0.022690936655773954	1.384162	76	198	0.01459574	
GO Biological Process	RNA catabolic process	34	9.935781e-23	3.845439475852941e-20	2.140985	205	0.0301648	313	0.0064753126715654955	1.391568	93	241	0.01786057	
GO Biological Process	macromolecular complex disassembly	39	2.1461e-21	7.241161512820512e-19	2.215999	178	0.02619188	116	0.000011037245108793105	1.642572	87	191	0.01670828	
GO Biological Process	protein complex disassembly	44	1.055988e-20	3.158124111818182e-18	2.334656	154	0.02266039	125	0.000031799281441600004	1.678314	74	159	0.01421164	
GO Biological Process	mitochondrial translational elongation	45	1.255998e-20	3.672817262666667e-18	3.358678	84	0.01236021	145	0.00007161991756413793	1.909116	45	85	0.008642212	
GO Biological Process	mitochondrial translation	51	1.105e-19	2.8511166666666666e-17	2.918481	98	0.01442025	156	0.0001132956158974359	1.786203	53	107	0.01017861	
GO Biological Process	mitochondrial translational termination	52	1.117346e-19	2.8275300026923073e-17	3.264571	83	0.01221307	165	0.0001467465362	1.865228	45	87	0.008642212	
GO Biological Process	translational elongation	54	1.981823e-19	4.8294090475925924e-17	2.804263	103	0.01515597	152	0.00010494146669736841	1.770856	55	112	0.0105627	
GO Biological Process	translational termination	66	4.78767e-18	9.545598413636365e-16	2.92123	89	0.01309594	139	0.00006876413427841726	1.859992	49	95	0.009410409	
GO Biological Process	cellular protein complex disassembly	76	2.304358e-17	3.989874595e-15	2.413889	119	0.0175103	183	0.0002600616046284153	1.688574	59	126	0.0113309	
GO Biological Process	rRNA processing	77	2.737165e-17	4.6777083422077925e-15	2.01189	177	0.02604473	244	0.0023129223752868856	1.416685	99	252	0.01901287	
GO Biological Process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	81	4.970639e-17	8.075140568024692e-15	2.651286	98	0.01442025	480	0.043512454081250006	1.466891	48	118	0.00921836	
GO Biological Process	negative regulation of intrinsic apoptotic signaling pathway	102	6.239892e-15	8.050072434117647e-13	2.36303	105	0.01545026	471	0.038745655747346064	1.534514	40	94	0.007681967	
GO Biological Process	regulation of cholesterol homeostasis	107	1.184332e-14	1.4565069895327102e-12	5.557046	33	0.004855798	429	0.027642783091841493	2.70458	9	12	0.001728442	
GO Biological Process	macroautophagy	126	1.219254e-13	1.2733463004761906e-11	2.049212	130	0.0191289	466	0.03768212369527898	1.418402	59	150	0.0113309	
GO Biological Process	ribonucleoprotein complex export from nucleus	141	7.551615e-13	7.047638424468086e-11	2.261974	97	0.0142731	214	0.0008737852707943924	1.644385	57	125	0.0109468	
GO Biological Process	multi-organism metabolic process	143	8.098484e-13	7.452304262657342e-11	2.109796	113	0.01662743	212	0.0007977432709433961	1.594537	65	147	0.0124832	
GO Cellular Component	mitochondrial large ribosomal subunit	33	4.40186e-21	2.3049739636363635e-19	4.613267	59	0.008681577	43	0.00003194186299534884	2.191947	31	51	0.005953524	
GO Cellular Component	mitochondrial ribosome	35	1.871971e-19	9.242188251428572e-18	3.485592	75	0.0110359	42	0.00003246933394285714	1.909116	45	85	0.008642212	
GO Cellular Component	ribosome	37	2.943646e-18	1.3747622399999999e-16	2.070925	175	0.02575044	40	0.00001798326576	1.543292	101	236	0.01939697	
GO Cellular Component	ribosomal subunit	38	4.524503e-17	2.0574582063157897e-15	2.25628	134	0.01971748	49	0.0005566364081632653	1.520413	78	185	0.01497983	
GO Cellular Component	large ribosomal subunit	39	5.336229e-17	2.364359926153846e-15	2.679954	96	0.01412596	58	0.0013068607779310344	1.630588	52	115	0.009986557	
GO Cellular Component	late endosome membrane	40	2.239246e-14	9.67354272e-13	2.199653	117	0.01721601	85	0.03270933232941176	1.454075	50	124	0.009602458	
GO Cellular Component	condensed chromosome, centromeric region	44	3.61244e-13	1.4187037090909092e-11	2.004355	132	0.01942319	65	0.0033372412061538465	1.585444	51	116	0.009794507	
GO Cellular Component	spliceosomal snRNP complex	51	1.438699e-11	4.874650729411765e-10	2.886595	55	0.008092996	79	0.0230189942278481	1.686728	29	62	0.005569426	
GO Cellular Component	catalytic step 2 spliceosome	54	2.495891e-11	7.9868512e-10	2.248744	85	0.01250736	64	0.0030170664000000002	1.652799	44	96	0.008450163	
GO Cellular Component	preribosome	55	1.597955e-10	5.020484072727273e-9	2.441256	66	0.009711595	54	0.000991384	1.803054	38	76	0.007297868	
GO Cellular Component	ESCRT complex	63	6.653731e-10	1.82502336e-8	3.643743	33	0.004855798	67	0.006738949826865672	2.189422	17	28	0.003264836	
GO Cellular Component	peptidase complex	82	4.89387e-8	0.0000010312935804878048	2.058912	69	0.01015303	98	0.046625037061224485	1.516204	37	88	0.007105819	
GO Cellular Component	ESCRT III complex	84	7.650007e-8	0.000001573715725714286	4.62368	19	0.002795762	78	0.019964815753846156	2.70458	9	12	0.001728442	
GO Cellular Component	preribosome, large subunit precursor	146	0.00003687472	0.0004364350421917808	2.658249	23	0.003384344	100	0.04667486976	2.01942	14	25	0.002688688	
GO Cellular Component	Golgi transport complex	214	0.0003584707	0.0028945671476635518	2.656983	17	0.002501471	77	0.018926373319480518	2.575791	10	14	0.001920492	
GO Cellular Component	mRNA cleavage and polyadenylation specificity factor complex	310	0.00332466	0.018532298322580645	2.355893	14	0.002060035	88	0.03732216872727273	2.404071	10	15	0.001920492	
GO Molecular Function	structural constituent of ribosome	10	6.575117e-17	2.7760143973999996e-14	2.31199	126	0.01854032	26	0.0025742329684615385	1.558194	70	162	0.01344344	
GO Molecular Function	peroxiredoxin activity	353	0.002805158	0.03355064327478753	3.143774	9	0.001324308	68	0.04731487987352941	3.155344	7	8	0.001344344	
Human Phenotype	Dysphonia	20	9.303169e-12	3.10400233685e-9	3.595883	41	0.006032961	51	0.02557980716470588	2.351809	15	23	0.002880737	
Human Phenotype	Overgrowth	105	1.398229e-7	0.000008886078206666667	3.412755	26	0.00382578	39	0.017478879774358972	2.524275	14	20	0.002688688	
Human Phenotype	Positive Romberg sign	239	0.00007799754	0.00217773047874477	5.97985	8	0.001177163	63	0.0480666887984127	3.606107	6	6	0.001152295	
Mouse Phenotype	abnormal lipoprotein lipase activity	410	0.00004389609	0.0010236354060731707	3.060536	18	0.002648617	214	0.03984409143084112	2.884886	8	10	0.001536393