# GREAT version 4.0.4	Species assembly: hg38	Association rule: Basal+extension: 5000 bp upstream, 1000 bp downstream, 1000000 bp max extension, curated regulatory domains included
# Ontology	 Term Name 	 Binom Rank 	 Binom Raw P-Value 	  Binom FDR Q-Val  	 Binom Fold Enrichment 	 Binom Observed Region Hits 	 Binom Region Set Coverage 	 Hyper Rank 	  Hyper FDR Q-Val  	 Hyper Fold Enrichment 	 Hyper Observed Gene Hits 	 Hyper Total Genes 	 Hyper Gene Set Coverage
GO Biological Process	gene silencing by miRNA	148	4.705543e-62	4.183800022770271e-60	2.546107	419	0.008022978	786	0.007154081205725191	1.23446	43	44	0.002892701	
GO Biological Process	posttranscriptional gene silencing	169	2.597843e-56	2.0227820140236683e-54	2.319053	455	0.008712303	635	0.0015872014861259842	1.238877	51	52	0.003430878	
GO Biological Process	negative regulation of Notch signaling pathway	170	2.953302e-56	2.2860294716470587e-54	2.556098	376	0.007199617	1170	0.04858650332564103	1.224891	32	33	0.002152708	
GO Biological Process	posttranscriptional gene silencing by RNA	173	1.505002e-55	1.1447584576878613e-53	2.31816	449	0.008597415	653	0.0019159425408728943	1.238401	50	51	0.003363606	
GO Biological Process	regulation of mitochondrial membrane permeability	185	4.055161e-52	2.8844250594054055e-50	2.015639	579	0.01108664	1094	0.038160715093235834	1.159346	67	73	0.004507232	
GO Biological Process	regulation of cholesterol metabolic process	303	3.207246e-38	1.3928762413861386e-36	2.086667	385	0.007371948	1014	0.02893631656706114	1.191668	50	53	0.003363606	
GO Biological Process	adherens junction assembly	322	2.759954e-36	1.127895487142857e-34	2.032287	389	0.00744854	1109	0.04166585548241659	1.226017	33	34	0.00221998	
GO Biological Process	apoptotic cell clearance	358	6.798398e-34	2.4988860134636875e-32	2.349026	261	0.004997607	984	0.024245671467479673	1.263169	27	27	0.001816347	
GO Biological Process	IRE1-mediated unfolded protein response	408	1.3875e-31	4.4750275735294116e-30	2.089214	314	0.006012446	1115	0.041535988139910315	1.176053	54	58	0.003632694	
GO Biological Process	regulation of cholesterol biosynthetic process	416	4.904687e-31	1.551460967139423e-29	2.052069	322	0.006165629	1149	0.044644192287206265	1.203018	40	42	0.002690885	
GO Biological Process	thyroid gland development	530	3.615476e-26	8.976612959245282e-25	2.199907	228	0.004365725	1124	0.04282564940302491	1.263169	24	24	0.001614531	
GO Biological Process	production of miRNAs involved in gene silencing by miRNA	539	1.306738e-25	3.190234757328386e-24	2.164911	231	0.004423169	984	0.024245671467479673	1.263169	27	27	0.001816347	
GO Biological Process	maintenance of protein localization in organelle	630	4.235019e-23	8.845811908095238e-22	2.318665	178	0.003408329	846	0.011059069359101656	1.263169	31	31	0.002085436	
GO Biological Process	cellular component disassembly involved in execution phase of apoptosis	692	2.78852e-21	5.3026206184971096e-20	2.324459	162	0.003101963	1022	0.02949838351663405	1.263169	26	26	0.001749075	
GO Biological Process	apoptotic nuclear changes	858	7.459128e-18	1.1439937686713285e-16	2.215868	148	0.002833892	1124	0.04282564940302491	1.263169	24	24	0.001614531	
Human Phenotype	Aplasia/Hypoplasia involving the femoral head and neck	32	1.328241e-29	2.7697975603125e-27	2.507327	199	0.003810436	418	0.03657388286602871	1.263169	26	26	0.001749075	
Human Phenotype	Aplasia/hypoplasia of the femur	74	3.023708e-25	2.7266491194594596e-23	2.053081	258	0.004940163	301	0.009869925669767441	1.263169	33	33	0.00221998	
Mouse Phenotype Single KO	abnormal interventricular septum thickness	118	2.585705e-39	2.0065509055084748e-37	2.068571	405	0.007754907	431	0.000909776207099768	1.263169	43	43	0.002892701	
Mouse Phenotype	increased lactate dehydrogenase level	451	5.45741e-25	1.1569467186252771e-23	2.053678	255	0.004882719	957	0.00897638930815047	1.263169	30	30	0.002018163