[M::bwa_idx_load_from_disk] read 0 ALT contigs [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26887, 1915850, 63647, 4711) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 146, 281) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 687) [M::mem_pestat] mean and std.dev: (153.93, 113.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 890) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 236, 306) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 562) [M::mem_pestat] mean and std.dev: (245.31, 97.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 690) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 443, 760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1730) [M::mem_pestat] mean and std.dev: (506.97, 341.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2215) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (745, 2036, 4826) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12988) [M::mem_pestat] mean and std.dev: (3045.38, 2750.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17069) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 162.316 CPU sec, 22.663 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (25655, 1913180, 63361, 4719) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (79, 150, 286) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700) [M::mem_pestat] mean and std.dev: (155.96, 115.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 907) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 235, 304) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558) [M::mem_pestat] mean and std.dev: (244.22, 96.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 685) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 444, 759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727) [M::mem_pestat] mean and std.dev: (507.58, 341.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2211) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (828, 2198, 4898) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13038) [M::mem_pestat] mean and std.dev: (3129.74, 2743.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17108) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 147.178 CPU sec, 12.705 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (26229, 1916223, 62723, 4720) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (77, 142, 268) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 650) [M::mem_pestat] mean and std.dev: (149.33, 107.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 841) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 234, 302) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 554) [M::mem_pestat] mean and std.dev: (242.37, 95.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 680) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 443, 760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1726) [M::mem_pestat] mean and std.dev: (505.67, 338.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2209) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (772, 2021, 4814) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12898) [M::mem_pestat] mean and std.dev: (3022.54, 2735.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16940) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 141.419 CPU sec, 10.765 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28069, 1926191, 63839, 4853) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 146, 274) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666) [M::mem_pestat] mean and std.dev: (153.26, 111.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 862) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 236, 305) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559) [M::mem_pestat] mean and std.dev: (244.67, 97.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 686) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 442, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734) [M::mem_pestat] mean and std.dev: (507.74, 341.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (777, 2118, 4894) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13128) [M::mem_pestat] mean and std.dev: (3090.49, 2767.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17245) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 149.802 CPU sec, 12.993 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29939, 1932828, 64132, 4858) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (75, 141, 267) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 651) [M::mem_pestat] mean and std.dev: (150.79, 110.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 843) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 308) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568) [M::mem_pestat] mean and std.dev: (246.26, 99.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 698) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 444, 768) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754) [M::mem_pestat] mean and std.dev: (511.45, 347.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2247) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (773, 2099, 4773) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12773) [M::mem_pestat] mean and std.dev: (3020.41, 2698.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16773) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 142.455 CPU sec, 11.584 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (31487, 1932233, 64863, 4838) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 142, 262) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630) [M::mem_pestat] mean and std.dev: (151.01, 107.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 814) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 239, 310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570) [M::mem_pestat] mean and std.dev: (248.47, 99.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 700) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 443, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740) [M::mem_pestat] mean and std.dev: (507.01, 342.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2228) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (769, 2164, 4813) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12901) [M::mem_pestat] mean and std.dev: (3080.79, 2753.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16945) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 162.996 CPU sec, 19.899 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33732, 1936970, 63883, 4887) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (74, 137, 251) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605) [M::mem_pestat] mean and std.dev: (146.54, 103.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 782) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 236, 306) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 564) [M::mem_pestat] mean and std.dev: (245.02, 98.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 693) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 445, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1739) [M::mem_pestat] mean and std.dev: (506.95, 342.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2227) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (760, 2048, 4791) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12853) [M::mem_pestat] mean and std.dev: (3016.37, 2720.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16884) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 142.760 CPU sec, 10.996 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35992, 1934755, 64194, 5020) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (75, 138, 246) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 588) [M::mem_pestat] mean and std.dev: (147.16, 101.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 759) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 238, 309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569) [M::mem_pestat] mean and std.dev: (247.54, 99.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 699) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737) [M::mem_pestat] mean and std.dev: (506.26, 341.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2224) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (798, 2164, 5016) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13452) [M::mem_pestat] mean and std.dev: (3101.32, 2733.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17670) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 146.978 CPU sec, 13.949 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35031, 1933246, 65075, 4883) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (75, 139, 252) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 606) [M::mem_pestat] mean and std.dev: (148.92, 104.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 783) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 239, 310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570) [M::mem_pestat] mean and std.dev: (248.28, 99.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 700) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 445, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734) [M::mem_pestat] mean and std.dev: (507.87, 342.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (765, 2106, 4781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12813) [M::mem_pestat] mean and std.dev: (3042.61, 2735.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16829) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 141.936 CPU sec, 11.716 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36676, 1932892, 65110, 4826) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 135, 243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 583) [M::mem_pestat] mean and std.dev: (145.44, 101.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 753) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 238, 309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569) [M::mem_pestat] mean and std.dev: (247.33, 99.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 699) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 445, 758) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720) [M::mem_pestat] mean and std.dev: (506.23, 339.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2201) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (783, 2013, 4782) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12780) [M::mem_pestat] mean and std.dev: (3023.14, 2699.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16779) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 158.818 CPU sec, 19.795 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (37210, 1933486, 64349, 4966) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 136, 242) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 580) [M::mem_pestat] mean and std.dev: (145.28, 101.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 749) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 237, 308) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 566) [M::mem_pestat] mean and std.dev: (246.53, 98.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 695) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 445, 766) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744) [M::mem_pestat] mean and std.dev: (510.13, 345.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2233) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (782, 2089, 4859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13013) [M::mem_pestat] mean and std.dev: (3047.33, 2725.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17090) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 144.035 CPU sec, 11.565 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34776, 1932310, 63963, 4864) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (74, 138, 251) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 605) [M::mem_pestat] mean and std.dev: (147.78, 104.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 782) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (245.79, 98.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 441, 758) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1722) [M::mem_pestat] mean and std.dev: (503.58, 338.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2204) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (774, 2125, 4807) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12873) [M::mem_pestat] mean and std.dev: (3040.67, 2707.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16906) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 149.951 CPU sec, 14.113 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34654, 1929554, 64612, 4900) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (76, 140, 253) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607) [M::mem_pestat] mean and std.dev: (149.75, 105.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 784) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 238, 309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567) [M::mem_pestat] mean and std.dev: (247.74, 98.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 696) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (274, 444, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1744) [M::mem_pestat] mean and std.dev: (507.98, 344.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2234) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (755, 1988, 4738) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12704) [M::mem_pestat] mean and std.dev: (3015.22, 2741.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16687) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 140.598 CPU sec, 11.520 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33485, 1929931, 65631, 4820) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 144, 260) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 624) [M::mem_pestat] mean and std.dev: (153.68, 108.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 806) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (182, 241, 313) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 575) [M::mem_pestat] mean and std.dev: (250.87, 100.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 706) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734) [M::mem_pestat] mean and std.dev: (506.87, 342.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (828, 2162, 5049) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13491) [M::mem_pestat] mean and std.dev: (3131.92, 2757.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17712) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 153.791 CPU sec, 16.592 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (38648, 1935481, 63930, 4809) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 134, 243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 583) [M::mem_pestat] mean and std.dev: (146.38, 103.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 753) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 236, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 567) [M::mem_pestat] mean and std.dev: (245.56, 98.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 697) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 768) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1752) [M::mem_pestat] mean and std.dev: (511.11, 346.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2244) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (753, 2046, 4718) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12648) [M::mem_pestat] mean and std.dev: (2979.73, 2682.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16613) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 138.255 CPU sec, 9.326 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35786, 1933136, 63564, 4891) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (74, 137, 248) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 596) [M::mem_pestat] mean and std.dev: (146.72, 103.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 770) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (245.91, 98.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 443, 761) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1731) [M::mem_pestat] mean and std.dev: (506.76, 342.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2216) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (785, 2149, 4934) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13232) [M::mem_pestat] mean and std.dev: (3096.01, 2762.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17381) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 148.374 CPU sec, 11.749 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36013, 1930882, 64935, 4948) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (75, 139, 251) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603) [M::mem_pestat] mean and std.dev: (148.95, 105.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 779) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (181, 239, 310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 568) [M::mem_pestat] mean and std.dev: (248.78, 99.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 697) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 444, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1738) [M::mem_pestat] mean and std.dev: (507.08, 342.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2225) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (788, 2070, 4928) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13208) [M::mem_pestat] mean and std.dev: (3072.95, 2742.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17348) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 143.051 CPU sec, 11.633 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35903, 1933140, 64617, 4749) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (75, 139, 250) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 600) [M::mem_pestat] mean and std.dev: (148.45, 104.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 775) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 239, 310) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 570) [M::mem_pestat] mean and std.dev: (248.37, 99.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 700) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 442, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1742) [M::mem_pestat] mean and std.dev: (506.15, 342.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2231) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (819, 2118, 4908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13086) [M::mem_pestat] mean and std.dev: (3089.77, 2745.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17175) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 158.831 CPU sec, 18.531 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40333, 1929951, 64215, 4829) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 134, 237) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (145.48, 100.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 729) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 238, 309) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569) [M::mem_pestat] mean and std.dev: (247.48, 99.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 699) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 447, 770) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1758) [M::mem_pestat] mean and std.dev: (509.87, 345.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2252) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (758, 2138, 5128) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13868) [M::mem_pestat] mean and std.dev: (3143.61, 2807.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 18238) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 142.680 CPU sec, 12.111 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39343, 1935763, 63709, 4785) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 134, 237) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (145.05, 100.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 729) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (246.16, 98.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 447, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1732) [M::mem_pestat] mean and std.dev: (508.70, 342.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2217) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (768, 2102, 4773) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12783) [M::mem_pestat] mean and std.dev: (3035.84, 2706.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16788) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 158.111 CPU sec, 19.311 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41067, 1931260, 63778, 4802) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (72, 132, 231) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 549) [M::mem_pestat] mean and std.dev: (142.75, 98.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 708) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (246.12, 98.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 442, 765) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743) [M::mem_pestat] mean and std.dev: (507.10, 342.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2232) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (779, 2062, 4873) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13061) [M::mem_pestat] mean and std.dev: (3063.27, 2744.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17155) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 142.453 CPU sec, 11.579 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36141, 1919605, 62367, 4721) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (71, 132, 238) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 572) [M::mem_pestat] mean and std.dev: (142.27, 100.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 739) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 234, 303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559) [M::mem_pestat] mean and std.dev: (242.29, 97.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 687) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 443, 767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1747) [M::mem_pestat] mean and std.dev: (509.71, 345.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2237) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (771, 2045, 4771) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12771) [M::mem_pestat] mean and std.dev: (3017.18, 2711.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16771) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 157.995 CPU sec, 17.966 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32203, 1920794, 62840, 4838) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (74, 136, 246) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590) [M::mem_pestat] mean and std.dev: (145.22, 102.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 762) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555) [M::mem_pestat] mean and std.dev: (242.98, 96.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 681) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 441, 759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1727) [M::mem_pestat] mean and std.dev: (505.05, 339.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2211) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (788, 2183, 4846) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12962) [M::mem_pestat] mean and std.dev: (3082.88, 2733.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17020) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 142.560 CPU sec, 11.728 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28842, 1915805, 64321, 4795) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 144, 265) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639) [M::mem_pestat] mean and std.dev: (151.25, 107.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 826) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 565) [M::mem_pestat] mean and std.dev: (245.93, 97.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 440, 762) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1734) [M::mem_pestat] mean and std.dev: (506.27, 340.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (752, 2067, 4949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13343) [M::mem_pestat] mean and std.dev: (3070.62, 2759.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17540) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 157.718 CPU sec, 18.445 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (32859, 1920843, 62493, 4848) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (73, 135, 243) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 583) [M::mem_pestat] mean and std.dev: (143.32, 100.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 753) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 232, 299) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 547) [M::mem_pestat] mean and std.dev: (240.23, 94.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 671) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1749) [M::mem_pestat] mean and std.dev: (508.71, 342.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2240) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (760, 2126, 4892) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13156) [M::mem_pestat] mean and std.dev: (3088.00, 2770.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17288) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 145.569 CPU sec, 11.912 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (28784, 1914518, 63961, 4821) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (76, 142, 264) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 640) [M::mem_pestat] mean and std.dev: (148.70, 106.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 828) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 235, 303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555) [M::mem_pestat] mean and std.dev: (243.22, 96.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 681) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 442, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737) [M::mem_pestat] mean and std.dev: (506.75, 341.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2224) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (797, 2150, 4964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13298) [M::mem_pestat] mean and std.dev: (3109.94, 2762.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17465) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 159.871 CPU sec, 19.386 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23011, 1910209, 62680, 4773) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (82, 155, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757) [M::mem_pestat] mean and std.dev: (161.51, 124.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 982) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 302) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 552) [M::mem_pestat] mean and std.dev: (242.80, 95.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 677) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 442, 759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1723) [M::mem_pestat] mean and std.dev: (504.10, 336.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2205) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (758, 2010, 4900) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13184) [M::mem_pestat] mean and std.dev: (3033.79, 2754.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17326) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 141.425 CPU sec, 11.772 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22909, 1908009, 63806, 4735) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (82, 155, 305) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 751) [M::mem_pestat] mean and std.dev: (161.04, 123.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 974) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 561) [M::mem_pestat] mean and std.dev: (246.28, 97.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 688) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (275, 442, 767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1751) [M::mem_pestat] mean and std.dev: (508.41, 344.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2243) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (794, 2106, 4841) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12935) [M::mem_pestat] mean and std.dev: (3067.98, 2740.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16982) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 160.292 CPU sec, 19.937 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (23624, 1913450, 62139, 4571) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 146, 285) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (152.06, 114.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 906) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (174, 232, 298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546) [M::mem_pestat] mean and std.dev: (239.53, 94.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 670) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 442, 758) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1720) [M::mem_pestat] mean and std.dev: (504.66, 336.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2201) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (760, 2050, 4753) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12739) [M::mem_pestat] mean and std.dev: (3025.45, 2720.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16732) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 141.160 CPU sec, 11.176 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22119, 1908177, 63451, 4782) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (81, 155, 315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 783) [M::mem_pestat] mean and std.dev: (161.41, 126.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1017) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 236, 304) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 556) [M::mem_pestat] mean and std.dev: (244.17, 96.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 682) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 445, 765) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1743) [M::mem_pestat] mean and std.dev: (508.47, 341.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2232) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (812, 2172, 5073) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13595) [M::mem_pestat] mean and std.dev: (3153.35, 2766.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17856) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 153.273 CPU sec, 18.787 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (22382, 1912408, 64484, 4778) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (84, 157, 316) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 780) [M::mem_pestat] mean and std.dev: (163.09, 127.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1012) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (180, 237, 306) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 558) [M::mem_pestat] mean and std.dev: (246.32, 96.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 684) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 764) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740) [M::mem_pestat] mean and std.dev: (507.76, 341.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2228) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (816, 2251, 5021) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13431) [M::mem_pestat] mean and std.dev: (3158.52, 2770.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17636) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 137.564 CPU sec, 9.445 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24475, 1909499, 63845, 4835) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (81, 151, 298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732) [M::mem_pestat] mean and std.dev: (157.38, 119.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 949) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 236, 305) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 559) [M::mem_pestat] mean and std.dev: (244.73, 96.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 686) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 444, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1737) [M::mem_pestat] mean and std.dev: (507.92, 342.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2224) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (755, 1992, 4665) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12485) [M::mem_pestat] mean and std.dev: (2979.55, 2704.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16395) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 143.312 CPU sec, 10.078 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (24332, 1914394, 63019, 4826) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (79, 148, 285) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697) [M::mem_pestat] mean and std.dev: (153.42, 113.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 903) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 235, 303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553) [M::mem_pestat] mean and std.dev: (243.43, 95.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 678) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 442, 763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1735) [M::mem_pestat] mean and std.dev: (507.40, 341.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2221) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (765, 2052, 4866) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13068) [M::mem_pestat] mean and std.dev: (3058.13, 2766.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17169) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 137.573 CPU sec, 10.442 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (27207, 1911960, 63213, 4659) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (76, 141, 267) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649) [M::mem_pestat] mean and std.dev: (148.91, 108.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 840) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 233, 301) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 553) [M::mem_pestat] mean and std.dev: (241.62, 95.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 679) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (276, 442, 755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1713) [M::mem_pestat] mean and std.dev: (505.05, 338.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2192) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (786, 2051, 4812) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12864) [M::mem_pestat] mean and std.dev: (3030.87, 2727.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16890) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 156.038 CPU sec, 18.977 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29177, 1932648, 65055, 5012) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (78, 146, 273) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663) [M::mem_pestat] mean and std.dev: (155.25, 113.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 858) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (181, 240, 312) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 574) [M::mem_pestat] mean and std.dev: (250.03, 100.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 705) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (277, 446, 771) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1759) [M::mem_pestat] mean and std.dev: (511.63, 348.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2253) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (769, 2048, 4638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12376) [M::mem_pestat] mean and std.dev: (2978.06, 2685.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16245) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 5673008 sequences (200000066 bp)... [M::mem_process_seqs] Processed 5714286 reads in 142.305 CPU sec, 11.209 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (35653, 1813327, 79353, 6069) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (70, 128, 255) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625) [M::mem_pestat] mean and std.dev: (139.17, 104.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 810) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 237, 307) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 563) [M::mem_pestat] mean and std.dev: (245.71, 97.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 691) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (289, 467, 804) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1834) [M::mem_pestat] mean and std.dev: (537.29, 360.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2349) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (751, 1939, 4659) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12475) [M::mem_pestat] mean and std.dev: (2962.75, 2700.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16383) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5673008 reads in 156.654 CPU sec, 19.279 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48681, 1469354, 121935, 9373) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (61, 105, 213) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 517) [M::mem_pestat] mean and std.dev: (111.80, 81.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 669) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (173, 230, 293) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 533) [M::mem_pestat] mean and std.dev: (235.59, 90.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 653) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 498, 848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1932) [M::mem_pestat] mean and std.dev: (574.09, 378.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2474) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (757, 2035, 4673) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12505) [M::mem_pestat] mean and std.dev: (2979.68, 2680.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16421) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5555556 sequences (200000016 bp)... [M::mem_process_seqs] Processed 5555556 reads in 139.659 CPU sec, 11.011 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56752, 1472443, 118954, 9423) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 100, 188) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 446) [M::mem_pestat] mean and std.dev: (106.68, 73.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 575) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (171, 228, 289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 525) [M::mem_pestat] mean and std.dev: (232.47, 89.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 643) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 498, 849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935) [M::mem_pestat] mean and std.dev: (574.07, 378.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2478) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (743, 1970, 4603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12323) [M::mem_pestat] mean and std.dev: (2955.91, 2698.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16183) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 160.879 CPU sec, 20.518 real sec [M::process] read 5687032 sequences (200000014 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47811, 1481163, 127008, 9724) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (62, 109, 231) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 569) [M::mem_pestat] mean and std.dev: (116.59, 89.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 738) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (239.22, 91.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 657) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 500, 851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1939) [M::mem_pestat] mean and std.dev: (574.89, 379.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2483) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (764, 2016, 4779) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12809) [M::mem_pestat] mean and std.dev: (3004.48, 2706.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16824) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5687032 reads in 140.810 CPU sec, 11.483 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52922, 1482100, 126322, 9858) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 103, 208) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 506) [M::mem_pestat] mean and std.dev: (109.87, 81.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 655) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (174, 232, 295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (237.25, 91.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 658) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 495, 848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934) [M::mem_pestat] mean and std.dev: (573.13, 380.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2477) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (768, 2073, 4796) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12852) [M::mem_pestat] mean and std.dev: (3040.39, 2731.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16880) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 163.698 CPU sec, 20.345 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53125, 1483234, 127185, 9930) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (61, 105, 210) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 508) [M::mem_pestat] mean and std.dev: (111.72, 80.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 657) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (239.15, 91.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 657) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 496, 847) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929) [M::mem_pestat] mean and std.dev: (572.68, 377.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2470) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (764, 2074, 4688) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12536) [M::mem_pestat] mean and std.dev: (3015.97, 2710.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16460) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 140.871 CPU sec, 11.673 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55717, 1480098, 126807, 9913) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 102, 200) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 482) [M::mem_pestat] mean and std.dev: (108.62, 78.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 623) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 233, 296) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536) [M::mem_pestat] mean and std.dev: (238.00, 91.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 656) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 499, 848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1930) [M::mem_pestat] mean and std.dev: (574.35, 378.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2471) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (766, 2021, 4698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12562) [M::mem_pestat] mean and std.dev: (2995.35, 2707.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16494) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 163.899 CPU sec, 20.999 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53695, 1479016, 128255, 9913) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 104, 208) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 504) [M::mem_pestat] mean and std.dev: (110.56, 80.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 652) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 233, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539) [M::mem_pestat] mean and std.dev: (238.69, 91.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 660) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (308, 502, 855) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949) [M::mem_pestat] mean and std.dev: (578.61, 383.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2496) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (749, 2049, 4723) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12671) [M::mem_pestat] mean and std.dev: (3002.33, 2715.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16645) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 139.336 CPU sec, 9.490 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48787, 1477910, 127533, 9814) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (63, 109, 227) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 555) [M::mem_pestat] mean and std.dev: (115.79, 87.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 719) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (178, 234, 298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538) [M::mem_pestat] mean and std.dev: (239.97, 91.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 658) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 497, 851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1941) [M::mem_pestat] mean and std.dev: (574.31, 380.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2486) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (779, 2029, 4678) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12476) [M::mem_pestat] mean and std.dev: (2987.81, 2687.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16375) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 140.213 CPU sec, 10.266 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52998, 1481599, 126803, 9750) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (61, 106, 214) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 520) [M::mem_pestat] mean and std.dev: (112.41, 82.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 673) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 233, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539) [M::mem_pestat] mean and std.dev: (238.56, 91.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 660) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 499, 852) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1942) [M::mem_pestat] mean and std.dev: (575.54, 380.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2487) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (737, 1919, 4504) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12038) [M::mem_pestat] mean and std.dev: (2916.96, 2688.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 15805) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 141.363 CPU sec, 9.669 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54976, 1479308, 127000, 9912) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 103, 203) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 489) [M::mem_pestat] mean and std.dev: (109.69, 78.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 632) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 233, 296) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 536) [M::mem_pestat] mean and std.dev: (238.17, 91.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 656) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 497, 850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1938) [M::mem_pestat] mean and std.dev: (574.41, 380.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2482) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (757, 2055, 4695) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12571) [M::mem_pestat] mean and std.dev: (2992.16, 2677.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16509) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 145.465 CPU sec, 10.016 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52253, 1480188, 127918, 9790) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (61, 105, 212) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 514) [M::mem_pestat] mean and std.dev: (112.42, 82.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 665) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (239.25, 91.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 657) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 498, 844) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1918) [M::mem_pestat] mean and std.dev: (572.59, 376.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2455) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (749, 2019, 4688) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12566) [M::mem_pestat] mean and std.dev: (2992.23, 2712.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16505) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5714286 sequences (200000010 bp)... [M::mem_process_seqs] Processed 5714286 reads in 142.649 CPU sec, 11.783 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56570, 1477736, 127915, 9823) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 104, 202) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 486) [M::mem_pestat] mean and std.dev: (110.63, 78.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 628) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (177, 234, 298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 540) [M::mem_pestat] mean and std.dev: (239.75, 91.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 661) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 499, 853) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945) [M::mem_pestat] mean and std.dev: (575.91, 379.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2491) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (777, 2059, 4749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12693) [M::mem_pestat] mean and std.dev: (3014.86, 2718.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16665) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 160.857 CPU sec, 20.003 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59589, 1479163, 127176, 9946) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 101, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 470) [M::mem_pestat] mean and std.dev: (108.72, 76.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 607) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (176, 233, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539) [M::mem_pestat] mean and std.dev: (238.71, 91.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 660) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 498, 849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1935) [M::mem_pestat] mean and std.dev: (574.67, 380.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2478) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (773, 1986, 4718) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12608) [M::mem_pestat] mean and std.dev: (2981.23, 2695.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16553) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5713138 sequences (200000032 bp)... [M::mem_process_seqs] Processed 5714286 reads in 141.621 CPU sec, 11.534 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65739, 1472537, 125389, 9762) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (57, 96, 181) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 429) [M::mem_pestat] mean and std.dev: (104.43, 72.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 553) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (174, 232, 295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (237.03, 91.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 658) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (308, 501, 850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1934) [M::mem_pestat] mean and std.dev: (574.89, 377.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2476) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (759, 2048, 4761) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12765) [M::mem_pestat] mean and std.dev: (3024.01, 2737.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16767) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5713138 reads in 162.956 CPU sec, 20.461 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56973, 1465341, 123524, 9640) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (58, 100, 196) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 472) [M::mem_pestat] mean and std.dev: (107.97, 77.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 610) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (174, 233, 298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 546) [M::mem_pestat] mean and std.dev: (238.52, 93.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 670) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 500, 854) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1950) [M::mem_pestat] mean and std.dev: (577.12, 382.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2498) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (748, 2052, 4818) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12958) [M::mem_pestat] mean and std.dev: (3022.35, 2734.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17028) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 139.420 CPU sec, 11.278 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56387, 1471003, 118983, 9433) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (58, 99, 189) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 451) [M::mem_pestat] mean and std.dev: (105.38, 73.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 582) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (171, 228, 291) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531) [M::mem_pestat] mean and std.dev: (233.27, 90.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 651) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 499, 853) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949) [M::mem_pestat] mean and std.dev: (576.47, 382.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2497) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (736, 1979, 4678) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12562) [M::mem_pestat] mean and std.dev: (2968.89, 2713.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16504) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 158.206 CPU sec, 18.247 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54942, 1467809, 122442, 9452) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 103, 201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 485) [M::mem_pestat] mean and std.dev: (110.06, 79.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 627) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (174, 231, 295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 537) [M::mem_pestat] mean and std.dev: (236.97, 91.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 658) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 499, 852) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1944) [M::mem_pestat] mean and std.dev: (574.81, 380.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2490) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (756, 1957, 4630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12378) [M::mem_pestat] mean and std.dev: (2960.59, 2698.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16252) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 139.975 CPU sec, 11.301 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55123, 1468674, 120684, 9673) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 102, 198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 474) [M::mem_pestat] mean and std.dev: (109.34, 77.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 612) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (172, 230, 293) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 535) [M::mem_pestat] mean and std.dev: (235.00, 91.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 656) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 500, 853) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1945) [M::mem_pestat] mean and std.dev: (575.72, 380.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2491) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (740, 1953, 4743) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12749) [M::mem_pestat] mean and std.dev: (2976.28, 2722.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16752) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 158.813 CPU sec, 18.420 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54252, 1470613, 119723, 9290) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 102, 197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 471) [M::mem_pestat] mean and std.dev: (108.64, 76.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 608) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (171, 229, 291) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 531) [M::mem_pestat] mean and std.dev: (233.51, 90.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 651) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 499, 851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943) [M::mem_pestat] mean and std.dev: (574.90, 379.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2489) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (739, 1987, 4714) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12664) [M::mem_pestat] mean and std.dev: (2975.42, 2711.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16639) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::process] read 5555556 sequences (200000016 bp)... [M::mem_process_seqs] Processed 5555556 reads in 139.782 CPU sec, 10.995 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52822, 1471066, 122390, 9603) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 104, 204) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 492) [M::mem_pestat] mean and std.dev: (110.30, 79.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 636) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 231, 294) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 532) [M::mem_pestat] mean and std.dev: (236.50, 90.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 651) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 498, 847) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929) [M::mem_pestat] mean and std.dev: (572.30, 376.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2470) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (758, 2001, 4779) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12821) [M::mem_pestat] mean and std.dev: (3001.11, 2719.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16842) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 160.741 CPU sec, 19.974 real sec [M::process] read 5555556 sequences (200000016 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56374, 1469808, 120330, 9444) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (59, 100, 191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 455) [M::mem_pestat] mean and std.dev: (106.89, 74.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 587) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (173, 229, 291) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 527) [M::mem_pestat] mean and std.dev: (233.90, 89.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 645) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (306, 498, 847) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1929) [M::mem_pestat] mean and std.dev: (572.90, 376.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2470) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (736, 1988, 4700) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12628) [M::mem_pestat] mean and std.dev: (2962.59, 2704.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16592) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5555556 reads in 138.970 CPU sec, 10.089 real sec [M::process] read 5650570 sequences (200000068 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50231, 1476182, 125008, 9660) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (60, 105, 218) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 534) [M::mem_pestat] mean and std.dev: (111.92, 84.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 692) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 232, 296) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 538) [M::mem_pestat] mean and std.dev: (237.65, 91.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 659) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 497, 851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1943) [M::mem_pestat] mean and std.dev: (574.01, 379.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2489) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (741, 1993, 4720) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12678) [M::mem_pestat] mean and std.dev: (2994.76, 2733.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16657) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5650570 reads in 144.187 CPU sec, 10.015 real sec [M::process] read 5714286 sequences (200000010 bp)... [M::process] read 3745218 sequences (131082630 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44260, 1484046, 130056, 10033) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (65, 115, 262) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656) [M::mem_pestat] mean and std.dev: (124.99, 103.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 853) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (179, 235, 299) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 539) [M::mem_pestat] mean and std.dev: (241.30, 91.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 659) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (308, 502, 855) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1949) [M::mem_pestat] mean and std.dev: (577.41, 382.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2496) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (783, 2131, 4798) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12828) [M::mem_pestat] mean and std.dev: (3048.95, 2710.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16843) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 5714286 reads in 143.125 CPU sec, 11.934 real sec [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (29421, 970613, 82761, 6413) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (61, 110, 248) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622) [M::mem_pestat] mean and std.dev: (118.19, 96.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 809) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (175, 232, 297) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 541) [M::mem_pestat] mean and std.dev: (238.31, 92.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 663) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (308, 502, 851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1937) [M::mem_pestat] mean and std.dev: (576.79, 379.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2480) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (801, 2118, 4727) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12579) [M::mem_pestat] mean and std.dev: (3033.14, 2708.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16505) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 3745218 reads in 105.443 CPU sec, 12.856 real sec [main] Version: 0.7.17-r1188 [main] CMD: bwa mem -SP5M -t 20 /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Euryarchaeota/Haloferax_volcanii_DS2_uid46845/bwa-indexes/all.fa /oak/stanford/groups/akundaje/marinovg/papers/2021_Haloferax-chromatin/2021-09-14-Hi-C-rerun/juicer-H.volcanii_WT_stationary-pooled/splits/reads_R1.fastq.gz /oak/stanford/groups/akundaje/marinovg/papers/2021_Haloferax-chromatin/2021-09-14-Hi-C-rerun/juicer-H.volcanii_WT_stationary-pooled/splits/reads_R2.fastq.gz [main] Real time: 1154.826 sec; CPU: 9324.929 sec slurmstepd: error: *** JOB 33560400 ON sh02-05n33 CANCELLED AT 2021-09-20T09:16:11 ***