# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_transf_49 PF13896.1 CBK19536.2 - 1.5e-18 66.9 5.0 1.2e-14 54.1 1.7 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK19536.2 - 0.0042 16.2 0.0 0.0089 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FadA PF09403.5 CBK19538.2 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA Ribosomal_L7Ae PF01248.21 CBK19539.2 - 0.0027 17.1 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WBP-1 PF11669.3 CBK19541.2 - 0.13 12.3 1.6 0.51 10.4 0.1 2.6 3 0 0 3 3 3 0 WW domain-binding protein 1 Ku_PK_bind PF08785.6 CBK19542.2 - 0.018 14.9 0.3 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like RNase_P_pop3 PF08228.6 CBK19542.2 - 0.077 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 Glyco_transf_49 PF13896.1 CBK19543.2 - 4.1e-09 35.9 4.5 2e-07 30.4 0.1 2.7 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK19543.2 - 0.00037 20.2 1.0 0.0012 18.5 0.3 2.0 1 1 1 2 2 2 2 F-box associated Pyr_redox_dim PF02852.17 CBK19544.2 - 1.6e-34 118.2 0.5 2.8e-34 117.4 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CBK19544.2 - 1.4e-16 61.0 0.0 1.9e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBK19544.2 - 1.3e-15 57.5 0.0 2.8e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK19544.2 - 0.0021 18.1 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBK19544.2 - 0.057 11.8 0.0 0.55 8.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_transf_90 PF05686.7 CBK19546.2 - 0.076 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Pterin_bind PF00809.17 CBK19547.2 - 1.7e-75 253.0 0.0 3.3e-75 252.0 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CBK19547.2 - 4.2e-39 133.1 0.0 7.2e-39 132.4 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glutaredoxin PF00462.19 CBK19547.2 - 1.1e-18 66.8 0.0 3.5e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CBK19547.2 - 0.0043 17.2 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBK19547.2 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PEP_mutase PF13714.1 CBK19547.2 - 0.022 13.9 0.2 0.77 8.9 0.1 2.5 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase FYRC PF05965.9 CBK19548.2 - 4.5e-08 32.7 0.0 9.6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 CBK19548.2 - 1.3e-06 27.7 0.0 3.4e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF35_N PF12172.3 CBK19548.2 - 0.001 18.8 1.9 0.0025 17.6 1.3 1.6 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) E1-E2_ATPase PF00122.15 CBK19549.2 - 5.4e-52 176.1 3.5 1e-51 175.1 2.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK19549.2 - 1.4e-41 141.9 9.6 1.4e-41 141.9 6.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK19549.2 - 2.3e-21 77.1 0.0 1.1e-15 58.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK19549.2 - 1.6e-13 50.4 0.0 3.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBK19549.2 - 2.3e-07 31.1 0.0 7e-06 26.3 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK19549.2 - 0.0045 16.6 0.5 0.036 13.6 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF663 PF04950.7 CBK19550.2 - 2e-70 237.0 0.0 2.3e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF663) WD40 PF00400.27 CBK19552.2 - 8.8e-35 117.3 12.5 2.1e-10 40.0 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBK19552.2 - 0.039 12.0 0.2 3 5.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ala_racemase_N PF01168.15 CBK19553.2 - 4.3e-13 49.3 0.0 5.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 CBK19553.2 - 0.003 17.7 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Mito_fiss_reg PF05308.6 CBK19553.2 - 0.063 12.6 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_6 PF14259.1 CBK19554.2 - 5.7e-10 39.0 0.0 1e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK19554.2 - 1.5e-08 34.1 0.3 1e-07 31.4 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19554.2 - 0.00021 21.0 0.1 0.00074 19.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBK19554.2 - 0.01 15.9 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DUF1877 PF08974.5 CBK19554.2 - 0.012 15.2 2.1 0.012 15.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) DUF2935 PF11155.3 CBK19554.2 - 0.29 11.2 11.1 1.8 8.6 1.4 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.5 CBK19554.2 - 0.63 10.1 16.5 0.24 11.5 2.0 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DNA_topoisoIV PF00521.15 CBK19554.2 - 3.4 6.4 11.8 6.9 5.3 7.2 2.1 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A TPR_MLP1_2 PF07926.7 CBK19554.2 - 3.9 7.2 25.8 2.6 7.7 7.9 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 CBK19554.2 - 4.1 5.7 16.8 3.5 5.9 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CBK19554.2 - 5.5 4.7 14.2 0.2 9.4 2.8 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family POR_N PF01855.14 CBK19555.2 - 2.9e-63 213.4 0.2 5e-63 212.6 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK19555.2 - 1.9e-26 93.0 0.0 4.4e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4_7 PF12838.2 CBK19555.2 - 3.1e-11 43.4 0.6 3.1e-05 24.2 9.1 3.4 2 2 3 5 5 5 3 4Fe-4S dicluster domain EKR PF10371.4 CBK19555.2 - 2.1e-10 40.0 0.0 6.5e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.16 CBK19555.2 - 1.1e-08 34.8 1.2 4.7e-08 32.7 0.2 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK19555.2 - 5.5e-05 22.5 12.3 0.00061 19.2 1.1 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.1 CBK19555.2 - 0.00016 21.6 16.2 0.00069 19.5 7.6 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK19555.2 - 0.00018 22.1 17.9 0.003 18.2 2.1 3.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 CBK19555.2 - 0.00033 20.9 14.0 0.00091 19.5 5.0 3.5 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK19555.2 - 0.00061 20.0 17.2 0.012 15.8 2.5 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK19555.2 - 0.0056 16.5 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_21 PF14697.1 CBK19555.2 - 0.021 14.6 18.9 0.011 15.6 9.5 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK19555.2 - 0.065 13.1 30.0 0.057 13.3 1.5 4.3 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBK19555.2 - 0.09 12.5 21.4 0.024 14.4 9.1 3.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain SH3_9 PF14604.1 CBK19556.2 - 5.3e-17 61.1 0.2 9.6e-16 57.1 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBK19556.2 - 2.3e-15 55.7 0.1 5.2e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBK19556.2 - 2.7e-13 49.2 0.1 1e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain BAR PF03114.13 CBK19556.2 - 2.2e-10 40.4 6.1 9.4e-10 38.3 4.3 2.1 1 1 1 2 2 2 1 BAR domain DUF3037 PF11236.3 CBK19556.2 - 0.086 12.9 0.2 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) Rtt106 PF08512.7 CBK19557.2 - 5.4e-14 51.9 0.1 1.1e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HLH PF00010.21 CBK19558.2 - 5.7e-12 45.1 1.1 1.6e-11 43.6 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GATase_7 PF13537.1 CBK19558.2 - 7.2e-11 41.9 0.0 3.4e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBK19558.2 - 7.9e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.16 CBK19558.2 - 1.9e-06 27.5 0.1 3.4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase PAS_9 PF13426.1 CBK19558.2 - 0.00095 19.5 0.0 0.01 16.1 0.0 2.6 3 0 0 3 3 3 1 PAS domain NPV_P10 PF05531.7 CBK19558.2 - 0.22 11.8 0.9 7.5 6.8 0.0 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Asn_synthase PF00733.16 CBK19559.2 - 1.7e-09 37.5 0.0 1.8e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Asparagine synthase PUF PF00806.14 CBK19560.2 - 3.3e-37 123.8 2.4 1.6e-05 24.1 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Aph-1 PF06105.7 CBK19561.2 - 6.1e-24 84.5 20.9 7.4e-24 84.3 14.5 1.0 1 0 0 1 1 1 1 Aph-1 protein TPR_12 PF13424.1 CBK19562.2 - 6.2e-05 22.8 4.3 3.6 7.5 0.3 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK19562.2 - 0.00043 19.8 0.8 2.2 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK19562.2 - 0.00065 19.2 2.6 0.62 9.7 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 CBK19562.2 - 0.0035 16.8 1.0 4.4 7.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK19562.2 - 0.013 15.4 1.0 8 6.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBK19562.2 - 0.033 14.3 5.0 0.086 12.9 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBK19562.2 - 0.062 13.6 0.3 27 5.1 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBK19563.2 - 6e-08 32.2 1.9 0.00028 20.4 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBK19563.2 - 0.0051 16.6 0.1 0.87 9.6 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK19563.2 - 0.008 16.8 0.0 0.3 11.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK19563.2 - 0.038 14.4 0.1 1.9 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK19563.2 - 0.05 13.2 1.8 3 7.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt PF00231.14 CBK19563.2 - 0.061 12.6 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 ATP synthase TPR_17 PF13431.1 CBK19563.2 - 0.11 12.7 0.2 3.3 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MRF_C1 PF13887.1 CBK19563.2 - 0.14 11.2 0.2 0.58 9.2 0.0 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 PRP1_N PF06424.7 CBK19564.2 - 0.77 10.0 7.3 2.9 8.2 5.0 1.9 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal WD40 PF00400.27 CBK19572.2 - 7e-19 66.9 12.4 2.6e-10 39.7 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 CBK19572.2 - 0.038 13.6 0.2 8.8 5.9 0.0 3.1 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A FeThRed_B PF02943.10 CBK19572.2 - 0.063 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain TAF PF02969.12 CBK19573.2 - 2.5e-05 24.1 0.2 4.8e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CBK19573.2 - 0.0098 15.9 0.2 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 EF-hand_1 PF00036.27 CBK19574.2 - 4.4e-14 50.6 1.3 1.8e-05 23.7 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBK19574.2 - 2.8e-13 48.5 3.2 0.00058 19.5 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBK19574.2 - 1.7e-11 44.0 3.7 4.7e-07 29.8 0.6 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 CBK19574.2 - 4.4e-05 23.0 2.2 0.11 12.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK19574.2 - 0.0019 17.4 4.2 0.38 10.1 0.0 4.1 5 0 0 5 5 5 1 EF hand YppF PF14178.1 CBK19574.2 - 0.0033 16.9 0.7 0.13 11.8 0.0 3.1 3 1 1 4 4 4 1 YppF-like protein EF-hand_10 PF14788.1 CBK19574.2 - 0.015 14.9 1.2 1.2 8.8 0.1 2.8 2 1 1 3 3 3 0 EF hand PMBR PF09373.5 CBK19574.2 - 0.1 12.5 0.3 0.8 9.7 0.0 2.5 3 0 0 3 3 3 0 Pseudomurein-binding repeat WD40 PF00400.27 CBK19575.2 - 0.00055 19.7 0.7 0.58 10.1 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 CBK19576.2 - 0.00015 21.5 1.0 0.039 14.0 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat Proteasom_PSMB PF10508.4 CBK19576.2 - 0.41 8.8 3.9 0.63 8.2 0.1 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Raptor_N PF14538.1 CBK19577.2 - 1.6e-36 125.4 0.0 2.6e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 CBK19577.2 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 Caspase domain MORN_2 PF07661.8 CBK19578.2 - 5.3 7.3 9.8 12 6.3 0.4 4.0 4 0 0 4 4 4 0 MORN repeat variant Fer4 PF00037.22 CBK19579.2 - 1.5e-13 49.7 15.7 5.5e-09 35.2 2.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CBK19579.2 - 4.6e-12 46.1 8.3 1.1e-11 44.8 5.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK19579.2 - 4.1e-11 42.9 20.1 1.4e-08 34.8 7.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK19579.2 - 3e-10 39.7 9.1 8.5e-10 38.2 6.3 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK19579.2 - 4.4e-10 39.4 17.9 2e-06 27.7 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK19579.2 - 2.3e-09 36.6 14.5 9.1e-06 25.2 1.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.1 CBK19579.2 - 1.6e-08 35.1 4.1 0.00045 20.8 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CBK19579.2 - 4.8e-08 32.7 7.0 0.00078 19.2 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK19579.2 - 7e-08 32.0 16.5 0.00077 19.2 3.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 CBK19579.2 - 1.1e-07 31.5 12.6 0.00047 20.2 2.2 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBK19579.2 - 5.7e-06 26.5 10.1 0.0003 21.0 7.2 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK19579.2 - 0.00016 21.9 13.4 0.031 14.7 1.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.2 CBK19579.2 - 0.00029 21.1 17.7 0.0017 18.7 3.2 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 CBK19579.2 - 0.00051 20.5 11.3 0.093 13.3 0.6 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 CBK19579.2 - 0.00091 19.5 13.4 0.16 12.3 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 CBK19579.2 - 0.18 11.9 6.3 0.35 11.0 0.2 2.5 1 1 1 2 2 2 0 c-SKI Smad4 binding domain RCC1 PF00415.13 CBK19580.2 - 0.0011 19.1 0.0 0.57 10.4 0.0 2.9 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK19580.2 - 0.0066 16.0 0.0 4 7.1 0.0 2.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Metallophos PF00149.23 CBK19581.2 - 2.8e-08 33.4 0.4 6.7e-08 32.1 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK19581.2 - 2.5e-07 30.6 0.0 3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 CBK19581.2 - 3.4e-06 26.3 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily DAGAT PF03982.8 CBK19582.2 - 5.5e-23 81.1 0.0 1.4e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Steroid_dh PF02544.11 CBK19583.2 - 9.8e-54 181.2 1.4 9.8e-54 181.2 1.0 1.8 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBK19583.2 - 3.2e-06 26.6 1.3 4.2e-06 26.2 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CBK19583.2 - 0.0098 15.9 1.2 0.0098 15.9 0.8 3.3 2 2 1 3 3 3 1 Phospholipid methyltransferase BP28CT PF08146.7 CBK19584.2 - 2.8e-26 92.1 0.7 2.8e-26 92.1 0.5 3.4 4 0 0 4 4 4 1 BP28CT (NUC211) domain HEAT_EZ PF13513.1 CBK19584.2 - 0.077 13.5 7.1 1 9.9 0.1 5.0 5 0 0 5 5 5 0 HEAT-like repeat SAM_decarbox PF01536.11 CBK19585.2 - 1.1e-76 257.6 0.1 2.6e-74 249.8 0.1 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PPTA PF01239.17 CBK19585.2 - 3.5e-25 86.2 13.1 3.8e-08 32.3 0.1 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat PDGF_N PF04692.8 CBK19586.2 - 0.14 12.6 3.2 0.26 11.8 2.2 1.4 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Zip PF02535.17 CBK19586.2 - 0.33 9.8 2.1 0.36 9.7 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OST3_OST6 PF04756.8 CBK19587.2 - 3.3e-10 39.7 0.9 3.3e-10 39.7 0.6 1.6 2 0 0 2 2 2 1 OST3 / OST6 family DUF2781 PF10914.3 CBK19587.2 - 0.0057 16.4 0.3 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) BRCA2 PF00634.13 CBK19588.2 - 2.4e-100 327.1 84.8 4.4e-06 25.8 0.4 21.8 17 4 5 22 22 22 20 BRCA2 repeat BRCA-2_OB1 PF09103.5 CBK19588.2 - 1.5e-22 79.4 0.0 3.9e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 HET-s_218-289 PF11558.3 CBK19588.2 - 6.5e-11 42.0 16.0 17 5.4 0.0 10.8 7 3 3 11 11 11 8 Het-s 218-289 BRCA-2_helical PF09169.5 CBK19588.2 - 2e-05 24.2 0.0 5.8e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 BRCA2, helical FmdE PF02663.9 CBK19588.2 - 0.0092 15.8 12.1 34 4.3 0.6 6.6 1 1 4 6 6 6 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Lung_7-TM_R PF06814.8 CBK19589.2 - 2.2e-42 145.0 23.2 2.4e-42 144.8 16.1 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBK19589.2 - 0.04 13.1 25.6 0.0095 15.1 15.3 1.7 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Bac_export_2 PF01312.14 CBK19589.2 - 0.093 11.5 13.1 0.15 10.9 9.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family LRR_8 PF13855.1 CBK19590.2 - 0.0018 17.9 0.6 0.025 14.3 0.1 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK19590.2 - 0.35 10.5 1.8 3.5 7.3 0.1 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Adap_comp_sub PF00928.16 CBK19592.2 - 9.4e-58 195.3 0.1 1.3e-57 194.8 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK19592.2 - 2e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rifin_STEVOR PF02009.11 CBK19593.2 - 0.005 16.5 0.8 0.007 16.0 0.6 1.2 1 0 0 1 1 1 1 Rifin/stevor family ABC2_membrane PF01061.19 CBK19594.2 - 1.9e-06 27.1 3.3 2.6e-06 26.7 2.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter MHC_I_C PF06623.6 CBK19594.2 - 0.57 9.7 5.6 4.8 6.7 3.9 2.3 1 1 0 1 1 1 0 MHC_I C-terminus ABC_tran PF00005.22 CBK19595.2 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RPOL_N PF14700.1 CBK19596.2 - 7.3e-23 81.3 0.7 9.8e-23 80.8 0.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF45 PF01863.12 CBK19596.2 - 1.4 8.7 3.9 8.4 6.1 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF45 RNA_pol PF00940.14 CBK19597.2 - 2e-157 523.8 0.0 2.4e-157 523.5 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CBK19597.2 - 9.8e-20 71.0 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sec_GG PF07549.9 CBK19597.2 - 0.069 12.4 0.0 0.22 10.8 0.0 1.8 1 0 0 1 1 1 0 SecD/SecF GG Motif Epimerase PF01370.16 CBK19598.2 - 1.9e-25 89.6 0.0 2.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBK19598.2 - 1.7e-13 50.1 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBK19598.2 - 4.7e-12 45.1 0.0 6.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK19598.2 - 3.8e-09 35.8 0.1 5.1e-08 32.1 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CBK19598.2 - 2e-06 26.9 0.0 8.2e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CBK19598.2 - 0.003 17.4 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CBK19598.2 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Prefoldin_2 PF01920.15 CBK19599.2 - 4.1e-05 23.3 0.1 4.4e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit WD40 PF00400.27 CBK19600.2 - 2.3e-48 160.4 26.5 3.3e-11 42.6 0.1 12.1 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 CBK19600.2 - 1.1e-18 67.1 0.1 2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Caldesmon PF02029.10 CBK19600.2 - 2.8e-08 32.6 31.6 3.7e-08 32.2 21.9 1.1 1 0 0 1 1 1 1 Caldesmon eIF2A PF08662.6 CBK19600.2 - 0.00011 21.9 0.8 8.7 6.0 0.0 5.4 4 1 3 7 7 7 2 Eukaryotic translation initiation factor eIF2A Mem_trans PF03547.13 CBK19600.2 - 0.025 12.9 0.3 0.036 12.3 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein PQQ_3 PF13570.1 CBK19600.2 - 0.15 12.3 6.6 3 8.2 0.1 4.5 5 0 0 5 5 4 0 PQQ-like domain DUF1513 PF07433.6 CBK19600.2 - 0.16 10.8 0.1 91 1.7 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1513) Daxx PF03344.10 CBK19600.2 - 0.22 9.9 50.6 0.36 9.2 35.1 1.2 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 CBK19600.2 - 0.4 9.2 21.8 0.58 8.7 15.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-T PF15511.1 CBK19600.2 - 1.3 8.1 32.9 1.9 7.6 22.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FLO_LFY PF01698.11 CBK19600.2 - 2.4 6.9 23.4 5.2 5.8 16.2 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein AvrE PF11725.3 CBK19600.2 - 8.6 3.2 18.8 12 2.7 13.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor BUD22 PF09073.5 CBK19600.2 - 8.8 5.2 59.2 12 4.8 41.0 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_S17 PF00366.15 CBK19601.2 - 1.4e-28 98.7 1.0 2.1e-28 98.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF913 PF06025.7 CBK19602.2 - 0.057 12.1 0.0 0.067 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Syndecan PF01034.15 CBK19602.2 - 0.077 12.6 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain CTP_transf_1 PF01148.15 CBK19603.2 - 0.00075 19.2 9.4 0.0024 17.5 6.5 1.7 1 1 0 1 1 1 1 Cytidylyltransferase family DUF1295 PF06966.7 CBK19604.2 - 6.5e-32 110.7 10.9 8.2e-32 110.3 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_transf_41 PF13844.1 CBK19605.2 - 3.3e-48 163.8 0.0 1.3e-29 102.5 0.0 2.0 1 1 0 2 2 2 2 Glycosyl transferase family 41 Cyclin_C PF02984.14 CBK19606.2 - 2.4e-08 33.9 0.8 3.5e-08 33.3 0.6 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CBK19606.2 - 0.006 16.1 2.5 0.11 12.0 0.1 2.5 3 0 0 3 3 3 2 Cyclin, N-terminal domain HEAT_2 PF13646.1 CBK19606.2 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats AAA PF00004.24 CBK19607.2 - 1.9e-77 257.8 0.0 3.6e-48 163.1 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBK19607.2 - 3.2e-08 33.3 1.1 0.00023 21.0 0.0 3.2 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CBK19607.2 - 4e-08 32.5 0.0 0.00011 21.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK19607.2 - 1.8e-07 31.3 0.0 0.003 17.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBK19607.2 - 2.5e-07 30.7 0.0 9.1e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBK19607.2 - 6.4e-07 29.1 0.3 0.0024 17.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBK19607.2 - 2.4e-06 27.4 0.0 0.00028 20.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK19607.2 - 2.4e-06 27.6 0.1 0.0017 18.3 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CBK19607.2 - 2.7e-05 23.6 0.8 0.99 8.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CBK19607.2 - 0.00031 19.9 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 CBK19607.2 - 0.001 18.8 0.0 0.12 12.0 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 CBK19607.2 - 0.0022 18.7 0.0 0.012 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBK19607.2 - 0.0025 17.9 0.0 0.039 14.1 0.0 2.6 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 CBK19607.2 - 0.0034 17.2 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CBK19607.2 - 0.0036 16.7 0.0 0.057 12.8 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBK19607.2 - 0.011 14.9 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CBK19607.2 - 0.013 14.6 0.1 0.22 10.5 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 CBK19607.2 - 0.013 14.9 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CBK19607.2 - 0.017 13.8 0.0 0.052 12.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 CBK19607.2 - 0.018 14.7 0.3 2 8.1 0.0 3.0 3 1 0 3 3 3 0 NTPase NB-ARC PF00931.17 CBK19607.2 - 0.023 13.5 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 CBK19607.2 - 0.023 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK19607.2 - 0.025 14.8 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CBK19607.2 - 0.032 13.9 0.0 0.4 10.3 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.1 CBK19607.2 - 0.033 13.9 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CBK19607.2 - 0.043 14.1 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBK19607.2 - 0.045 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 CBK19607.2 - 0.062 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 CBK19607.2 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TRP PF06011.7 CBK19608.2 - 3.6e-05 22.5 0.1 4.3e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel ODV-E18 PF10717.4 CBK19608.2 - 0.0003 20.1 0.2 0.00061 19.1 0.2 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF1517 PF07466.6 CBK19608.2 - 0.0071 15.3 0.2 0.0093 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) YodL PF14191.1 CBK19608.2 - 0.011 16.2 0.1 0.017 15.6 0.0 1.2 1 0 0 1 1 1 0 YodL-like RBP_receptor PF14752.1 CBK19608.2 - 0.022 13.1 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor EpsG PF14897.1 CBK19608.2 - 0.065 12.1 0.2 0.093 11.6 0.2 1.2 1 0 0 1 1 1 0 EpsG family TMEM154 PF15102.1 CBK19608.2 - 0.1 12.2 0.6 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family DUF3753 PF12575.3 CBK19608.2 - 0.29 10.9 4.1 0.67 9.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) SecG PF03840.9 CBK19608.2 - 4.2 7.1 11.3 0.2 11.4 2.7 2.5 2 1 1 3 3 3 0 Preprotein translocase SecG subunit SHMT PF00464.14 CBK19609.2 - 5.3e-176 584.8 0.0 6.2e-176 584.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBK19609.2 - 0.00089 18.4 0.2 0.0017 17.5 0.1 1.6 2 1 0 2 2 2 1 Beta-eliminating lyase ACBP PF00887.14 CBK19609.2 - 0.039 13.6 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Acyl CoA binding protein SHMT PF00464.14 CBK19610.2 - 6.4e-176 584.5 0.0 7.5e-176 584.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBK19610.2 - 0.0011 18.2 0.3 0.0026 16.9 0.0 1.6 2 1 0 2 2 2 1 Beta-eliminating lyase ACBP PF00887.14 CBK19610.2 - 0.043 13.4 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Acyl CoA binding protein LRR_4 PF12799.2 CBK19611.2 - 0.0081 15.7 1.3 0.46 10.1 0.1 3.3 2 2 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK19611.2 - 0.014 15.1 0.9 6.4 6.6 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeat zf-DHHC PF01529.15 CBK19612.2 - 3.6e-08 33.0 19.7 2e-07 30.5 13.6 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase ADH_N PF08240.7 CBK19612.2 - 0.0092 15.7 0.8 0.012 15.3 0.5 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FH2 PF02181.18 CBK19613.2 - 0.00062 18.7 0.0 0.00074 18.5 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF357 PF04010.8 CBK19613.2 - 0.0069 16.0 0.0 0.028 14.1 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF357) Sec8_exocyst PF04048.9 CBK19613.2 - 0.01 15.4 0.9 0.015 14.9 0.6 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain WXG100 PF06013.7 CBK19613.2 - 0.027 14.4 0.1 0.033 14.1 0.1 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Tape_meas_lam_C PF09718.5 CBK19613.2 - 0.051 13.5 2.4 0.12 12.2 1.6 1.5 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Potyvirid-P3 PF13608.1 CBK19613.2 - 0.11 11.6 0.7 0.13 11.3 0.5 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein YtxH PF12732.2 CBK19613.2 - 0.11 12.8 0.2 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 YtxH-like protein FlaC_arch PF05377.6 CBK19613.2 - 0.12 12.2 0.3 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CBK19613.2 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliE PF02049.13 CBK19613.2 - 0.14 12.2 1.6 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Annexin PF00191.15 CBK19613.2 - 0.14 12.0 0.1 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Annexin DUF3829 PF12889.2 CBK19613.2 - 0.21 10.7 2.3 0.49 9.5 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Pkinase PF00069.20 CBK19614.2 - 5.7e-79 264.9 0.0 6.5e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK19614.2 - 2.2e-43 148.2 0.0 2.7e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK19614.2 - 3e-06 26.3 0.0 6.7e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBK19614.2 - 1.3e-05 24.5 0.2 2.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBK19614.2 - 0.00041 19.4 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK19614.2 - 0.0035 17.1 0.1 0.056 13.1 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family YukC PF10140.4 CBK19614.2 - 0.12 10.9 0.9 0.39 9.2 0.3 1.8 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Glyco_transf_92 PF01697.22 CBK19615.2 - 1.3e-10 41.1 0.3 2.2e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 CBK19615.2 - 0.00023 21.4 0.0 0.0039 17.4 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Lon_C PF05362.8 CBK19616.2 - 8e-71 237.5 0.0 4.5e-59 199.2 0.0 3.0 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CBK19616.2 - 5.4e-24 84.8 0.0 1.7e-23 83.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CBK19616.2 - 1.6e-09 37.3 0.0 3.9e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON PF02190.11 CBK19616.2 - 1.7e-09 37.6 0.3 6.1e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CBK19616.2 - 5.4e-07 29.4 0.0 2.6e-06 27.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBK19616.2 - 6.4e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBK19616.2 - 1.3e-05 26.0 0.7 0.0001 23.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBK19616.2 - 4.1e-05 22.7 0.0 0.00037 19.6 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBK19616.2 - 4.1e-05 22.4 3.6 0.00013 20.8 0.1 2.5 3 0 0 3 3 3 1 TIP49 C-terminus AAA_16 PF13191.1 CBK19616.2 - 4.6e-05 23.4 0.1 0.00065 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 CBK19616.2 - 5.2e-05 22.0 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_23 PF13476.1 CBK19616.2 - 6.5e-05 23.3 4.7 0.0027 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBK19616.2 - 0.00045 19.6 1.0 0.0025 17.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF1338 PF07063.8 CBK19616.2 - 0.00098 18.2 0.5 0.0018 17.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) AAA_14 PF13173.1 CBK19616.2 - 0.0013 18.6 0.0 0.005 16.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CBK19616.2 - 0.0014 18.7 1.8 0.045 13.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBK19616.2 - 0.0015 18.2 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBK19616.2 - 0.0029 17.4 0.1 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK19616.2 - 0.0058 16.9 0.4 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBK19616.2 - 0.0082 15.8 0.1 0.063 12.9 0.0 2.5 4 0 0 4 4 3 1 NACHT domain IstB_IS21 PF01695.12 CBK19616.2 - 0.0082 15.5 0.2 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBK19616.2 - 0.0084 16.2 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBK19616.2 - 0.028 13.5 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CBK19616.2 - 0.037 14.3 0.3 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 CBK19616.2 - 0.044 13.7 0.5 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CBK19616.2 - 0.047 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CBK19616.2 - 0.049 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MobB PF03205.9 CBK19616.2 - 0.1 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBK19616.2 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CBK19616.2 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain CTDII PF01556.13 CBK19617.2 - 9.8e-21 73.4 0.0 4.2e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 CBK19617.2 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain CK_II_beta PF01214.13 CBK19618.2 - 1.6e-70 236.3 2.2 1.9e-70 236.1 1.5 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Herpes_UL92 PF03048.9 CBK19618.2 - 0.046 13.2 0.5 0.09 12.3 0.3 1.4 1 0 0 1 1 1 0 UL92 family Collagen PF01391.13 CBK19619.2 - 0.00034 20.0 26.4 0.027 14.0 1.7 3.3 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) DUF2217 PF10265.4 CBK19619.2 - 4 6.0 13.0 6.3 5.4 9.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4407 PF14362.1 CBK19619.2 - 6.1 5.6 32.2 12 4.7 22.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-binding PF00249.26 CBK19620.2 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain U-box PF04564.10 CBK19620.2 - 0.0032 17.3 0.1 0.0063 16.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain SICA_C PF12879.2 CBK19620.2 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain Atrophin-1 PF03154.10 CBK19620.2 - 0.29 9.2 3.2 0.37 8.8 2.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family EB1 PF03271.12 CBK19621.2 - 7.2e-10 38.7 0.9 1.9e-09 37.4 0.6 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CBK19621.2 - 2.2e-08 34.1 0.4 8.6e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBK19621.2 - 8.4e-05 22.1 0.4 0.00023 20.7 0.0 1.9 2 0 0 2 2 2 1 CAMSAP CH domain Prefoldin_2 PF01920.15 CBK19621.2 - 0.14 11.9 3.8 0.088 12.5 1.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit TBPIP PF07106.8 CBK19621.2 - 0.33 10.4 3.8 0.36 10.3 1.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 CBK19621.2 - 0.34 10.6 7.3 0.24 11.1 1.4 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Uds1 PF15456.1 CBK19621.2 - 0.37 10.7 4.0 1.1 9.3 2.8 1.8 1 1 0 1 1 1 0 Up-regulated During Septation SWIM PF04434.12 CBK19622.2 - 1.3e-06 27.7 0.1 3.6e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger E2_bind PF08825.5 CBK19622.2 - 0.0088 15.7 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 E2 binding domain MULE PF10551.4 CBK19622.2 - 0.016 15.3 0.1 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 MULE transposase domain Mucin PF01456.12 CBK19622.2 - 0.33 10.7 35.8 0.59 9.9 24.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIA PF03153.8 CBK19622.2 - 0.4 10.5 6.0 0.57 10.0 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CBK19622.2 - 9.8 5.2 22.6 16 4.5 15.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 CBK19623.2 - 1.6e-05 24.5 0.1 0.14 12.0 0.0 3.2 3 1 0 3 3 3 2 WD domain, G-beta repeat Mto2_bdg PF12808.2 CBK19623.2 - 0.0092 16.0 2.9 0.011 15.8 0.9 1.9 1 1 1 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region MCC-bdg_PDZ PF10506.4 CBK19623.2 - 0.022 14.5 1.2 0.052 13.3 0.8 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome IncA PF04156.9 CBK19623.2 - 0.053 13.1 4.8 0.093 12.3 3.3 1.4 1 0 0 1 1 1 0 IncA protein CorA PF01544.13 CBK19623.2 - 0.069 12.1 1.1 0.13 11.2 0.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4510 PF14971.1 CBK19623.2 - 0.078 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) MbeD_MobD PF04899.7 CBK19623.2 - 0.089 12.7 0.3 0.089 12.7 0.2 1.8 2 0 0 2 2 2 0 MbeD/MobD like WD40_alt PF14077.1 CBK19623.2 - 0.098 12.3 1.3 0.21 11.2 0.9 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF724 PF05266.9 CBK19623.2 - 0.14 11.7 5.3 0.029 14.0 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ACCA PF03255.9 CBK19623.2 - 0.15 11.5 0.8 0.32 10.5 0.6 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SlyX PF04102.7 CBK19623.2 - 0.25 11.7 2.7 0.62 10.4 1.9 1.7 1 1 0 1 1 1 0 SlyX Mnd1 PF03962.10 CBK19623.2 - 0.29 10.7 7.3 0.1 12.2 1.1 2.1 2 0 0 2 2 2 0 Mnd1 family bZIP_2 PF07716.10 CBK19623.2 - 0.39 10.5 7.8 1.1 9.1 0.9 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Herpes_BLRF2 PF05812.7 CBK19623.2 - 0.68 9.7 9.9 0.89 9.3 0.2 3.3 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DivIC PF04977.10 CBK19623.2 - 1 8.8 7.1 2.2 7.8 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 CBK19623.2 - 4.5 7.3 9.7 0.35 10.8 1.6 2.5 2 1 1 3 3 3 0 bZIP transcription factor Fer2 PF00111.22 CBK19624.2 - 2.5e-06 27.1 0.1 4.4e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cytochrome_C7 PF14522.1 CBK19624.2 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c7 Cytochrome_C554 PF13435.1 CBK19624.2 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime GSu_C4xC__C2xCH PF09698.5 CBK19624.2 - 0.1 12.7 3.3 0.11 12.6 0.8 2.1 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Transcrip_reg PF01709.15 CBK19625.2 - 8e-60 201.8 0.1 9.7e-60 201.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator PRMT5 PF05185.11 CBK19626.2 - 1.8e-15 56.8 0.0 2.2e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 CBK19626.2 - 5.6e-12 45.4 0.0 9.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBK19626.2 - 1.9e-11 43.6 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CBK19626.2 - 6.2e-10 39.1 0.0 6.4e-09 35.8 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK19626.2 - 1e-09 38.9 0.0 1.9e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK19626.2 - 8e-08 31.8 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBK19626.2 - 3.2e-07 30.7 0.0 1.1e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBK19626.2 - 4.9e-06 25.8 0.1 6.7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 CBK19626.2 - 1.8e-05 24.4 0.1 3.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 CBK19626.2 - 2.6e-05 23.9 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBK19626.2 - 0.0021 16.8 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CBK19626.2 - 0.0032 17.8 0.0 0.011 16.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 CBK19626.2 - 0.0035 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 CBK19626.2 - 0.021 15.2 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CBK19626.2 - 0.026 14.0 0.1 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CBK19626.2 - 0.03 13.7 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 CBK19626.2 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 CBK19626.2 - 0.1 13.4 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.16 CBK19627.2 - 8.9e-29 100.4 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBK19627.2 - 3.9e-07 29.8 2.1 1.6e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III PNTB PF02233.11 CBK19628.2 - 1.6e-161 538.1 14.4 1.6e-161 538.1 10.0 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CBK19628.2 - 1.3e-45 154.9 1.0 3e-45 153.8 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CBK19628.2 - 1.7e-43 147.8 0.6 5.5e-43 146.2 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 CBK19628.2 - 4.1e-33 113.4 2.7 4.1e-33 113.4 1.9 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 CBK19628.2 - 0.0004 19.5 0.7 0.49 9.5 0.0 3.4 3 1 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CBK19628.2 - 0.00052 20.3 0.2 0.0019 18.5 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBK19628.2 - 0.0059 16.6 1.8 0.29 11.1 0.3 3.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_M PF00205.17 CBK19628.2 - 0.013 15.2 0.2 0.17 11.6 0.2 2.7 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 CBK19628.2 - 0.058 13.2 1.1 0.18 11.6 0.5 2.1 2 2 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CBK19628.2 - 0.18 11.9 3.3 21 5.2 0.2 3.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L13 PF00572.13 CBK19629.2 - 9.3e-22 77.4 0.6 1.2e-21 77.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 Rhomboid PF01694.17 CBK19630.2 - 1.6e-06 28.2 17.7 2.2e-06 27.7 12.3 1.2 1 0 0 1 1 1 1 Rhomboid family C_GCAxxG_C_C PF09719.5 CBK19630.2 - 0.021 14.6 0.2 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) FixP_N PF14715.1 CBK19630.2 - 7.3 6.0 12.6 0.18 11.2 1.5 2.9 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ATP_bind_3 PF01171.15 CBK19631.2 - 3.4e-16 59.2 0.0 5.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ScdA_N PF04405.9 CBK19631.2 - 0.098 12.0 0.1 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) WEMBL PF05701.6 CBK19632.2 - 6.1e-09 34.8 252.8 0.00015 20.4 74.8 4.1 1 1 2 3 3 3 3 Weak chloroplast movement under blue light Auto_anti-p27 PF06677.7 CBK19632.2 - 0.015 15.0 1.4 0.028 14.1 0.9 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CAF1 PF04857.15 CBK19633.2 - 1.1e-39 136.3 0.0 1.7e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Piwi PF02171.12 CBK19634.2 - 9.7e-73 244.7 0.0 1.4e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBK19634.2 - 3.7e-19 68.3 5.3 1e-17 63.6 2.4 2.4 2 0 0 2 2 2 2 PAZ domain DUF1785 PF08699.5 CBK19634.2 - 0.0038 16.5 0.1 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Menin PF05053.8 CBK19634.2 - 0.077 11.1 5.3 0.12 10.5 3.6 1.2 1 0 0 1 1 1 0 Menin PP2C PF00481.16 CBK19637.2 - 4.5e-17 62.2 0.0 5.4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Clathrin PF00637.15 CBK19638.2 - 1.1e-17 63.9 11.8 2.6e-11 43.3 1.2 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS TPR_11 PF13414.1 CBK19638.2 - 0.092 12.4 2.5 0.91 9.2 0.1 3.3 3 0 0 3 3 3 0 TPR repeat Apc3 PF12895.2 CBK19638.2 - 1.7 8.8 7.7 19 5.5 0.1 4.1 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 CBK19638.2 - 1.8 8.7 4.2 13 6.0 0.1 4.2 4 0 0 4 4 4 0 PPR repeat zf-C3HC4_2 PF13923.1 CBK19639.2 - 0.00058 19.8 7.2 0.00058 19.8 5.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK19639.2 - 0.0013 18.4 7.4 0.0029 17.4 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain VPS11_C PF12451.3 CBK19639.2 - 0.0064 16.3 0.1 0.0097 15.7 0.1 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 CBK19639.2 - 0.012 15.3 8.0 0.012 15.3 5.5 1.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBK19639.2 - 0.034 13.8 5.9 0.034 13.8 4.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBK19639.2 - 0.29 11.2 7.0 0.5 10.5 4.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Di19 PF05605.7 CBK19639.2 - 0.33 11.1 4.2 0.48 10.6 2.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4 PF00097.20 CBK19639.2 - 1.3 8.7 11.9 0.047 13.3 4.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBK19639.2 - 1.4 8.6 5.3 0.64 9.7 2.0 1.8 2 0 0 2 2 2 0 RING-type zinc-finger Med27 PF11571.3 CBK19639.2 - 9.3 6.4 8.5 5.9 7.0 2.2 2.2 1 1 1 2 2 2 0 Mediator complex subunit 27 PC_rep PF01851.17 CBK19640.2 - 1e-05 25.4 5.6 0.24 11.7 0.0 6.2 6 0 0 6 6 6 2 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBK19640.2 - 9.7e-05 22.5 2.0 0.00052 20.2 0.3 2.6 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 CBK19640.2 - 0.34 10.8 3.0 1.3 8.9 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat XRN_N PF03159.13 CBK19642.2 - 2.9e-76 255.9 0.0 3.9e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Ribosom_S12_S23 PF00164.20 CBK19643.2 - 1.2e-37 128.0 1.7 1.5e-37 127.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L18e PF00828.14 CBK19644.2 - 1.2e-31 109.8 0.0 1.5e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Fibrillarin PF01269.12 CBK19645.2 - 2.1e-108 360.5 0.0 2.5e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBK19645.2 - 4.9e-05 22.9 0.1 0.0001 21.8 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBK19645.2 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CBK19645.2 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pro_isomerase PF00160.16 CBK19647.2 - 8.2e-47 159.2 0.0 1.5e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CBK19647.2 - 2.8e-11 42.8 0.5 0.0021 17.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SAP PF02037.22 CBK19647.2 - 2.9e-06 26.6 0.0 4.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-GRF PF06839.7 CBK19648.2 - 2.6e-16 59.2 3.2 2.6e-16 59.2 2.3 2.5 3 0 0 3 3 3 1 GRF zinc finger zf-CCHC PF00098.18 CBK19648.2 - 6.2e-08 32.1 0.5 1.4e-07 31.1 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CBK19648.2 - 0.0027 17.3 0.6 0.0058 16.2 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CBK19648.2 - 0.016 14.9 2.2 0.029 14.0 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle U79_P34 PF03064.11 CBK19648.2 - 0.076 12.5 3.4 0.085 12.3 2.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Topoisom_bac PF01131.15 CBK19649.2 - 2e-61 208.0 0.0 3e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBK19649.2 - 2.3e-14 53.1 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Zn-ribbon_8 PF09723.5 CBK19649.2 - 0.14 12.1 7.1 29 4.7 0.7 4.3 3 1 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 CBK19649.2 - 0.38 10.4 10.5 5.3 6.7 1.7 3.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.8 CBK19649.2 - 2.9 7.6 5.4 26 4.5 0.0 3.0 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Cys_rich_KTR PF14205.1 CBK19649.2 - 6.7 6.2 8.9 23 4.5 0.1 3.4 3 0 0 3 3 3 0 Cysteine-rich KTR MORN PF02493.15 CBK19651.2 - 6.2e-08 31.9 33.7 0.00024 20.6 0.1 6.8 7 0 0 7 7 7 4 MORN repeat MORN_2 PF07661.8 CBK19651.2 - 2.9e-06 26.6 7.1 0.35 11.0 0.0 7.2 7 0 0 7 7 7 2 MORN repeat variant Nup35_RRM PF05172.8 CBK19651.2 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif F-box-like PF12937.2 CBK19652.2 - 0.00025 20.6 0.2 0.00055 19.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like BCDHK_Adom3 PF10436.4 CBK19653.2 - 8.1e-17 61.2 0.0 1.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBK19653.2 - 2.3e-16 59.4 0.0 2.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK19653.2 - 0.00013 21.5 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF2_N PF00176.18 CBK19654.2 - 5.3e-65 219.1 1.1 8.8e-65 218.4 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK19654.2 - 2.2e-16 59.4 0.0 5.6e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FYRN PF05964.9 CBK19654.2 - 6.5e-13 47.9 0.2 1.3e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus ResIII PF04851.10 CBK19654.2 - 3.9e-05 23.5 0.0 0.0014 18.5 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK19654.2 - 0.00058 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBK19654.2 - 0.015 14.1 0.1 0.04 12.7 0.1 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 PBP_sp32 PF07222.7 CBK19654.2 - 0.038 13.1 0.7 0.081 12.0 0.5 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Biotin_lipoyl_2 PF13533.1 CBK19654.2 - 0.099 12.3 0.3 0.29 10.8 0.2 1.8 1 1 0 1 1 1 0 Biotin-lipoyl like RNA_pol_Rpb5_C PF01191.14 CBK19655.2 - 2.3e-32 110.4 0.2 4.2e-32 109.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CBK19655.2 - 3e-19 69.2 1.6 5.8e-19 68.2 0.6 1.8 1 1 1 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Pyr_excise PF03013.9 CBK19655.2 - 0.065 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase ERCC4 PF02732.10 CBK19655.2 - 0.075 12.7 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 ERCC4 domain Pkinase PF00069.20 CBK19656.2 - 4.6e-45 153.8 0.7 7.4e-44 149.8 0.5 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK19656.2 - 3.1e-27 95.2 0.0 4e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK19656.2 - 0.00012 21.1 0.0 0.0012 17.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBK19656.2 - 0.00018 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBK19656.2 - 0.0002 20.4 0.1 0.00029 19.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK19656.2 - 0.0064 16.0 0.3 0.0088 15.6 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBK19656.2 - 0.0087 14.8 0.2 0.012 14.4 0.2 1.3 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase YukC PF10140.4 CBK19656.2 - 0.019 13.5 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF2462 PF09495.5 CBK19657.2 - 3.8e-07 30.7 16.9 3.8e-07 30.7 11.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2462) MetJ PF01340.15 CBK19657.2 - 0.55 10.0 3.3 0.87 9.3 2.3 1.3 1 1 0 1 1 1 0 Met Apo-repressor, MetJ DEAD PF00270.24 CBK19658.2 - 7.1e-43 146.0 0.2 5.8e-41 139.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK19658.2 - 2.6e-27 94.5 0.4 1.7e-26 91.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBK19658.2 - 0.00081 17.9 0.0 0.035 12.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) ResIII PF04851.10 CBK19658.2 - 0.0012 18.6 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIB PF00382.14 CBK19658.2 - 0.039 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat PX PF00787.19 CBK19659.2 - 0.013 15.2 0.4 0.041 13.6 0.0 2.0 2 0 0 2 2 2 0 PX domain zf-C4pol PF14260.1 CBK19659.2 - 0.086 12.8 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF3169 PF11368.3 CBK19660.2 - 0.016 14.4 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1460 PF07313.7 CBK19660.2 - 0.095 11.8 0.0 0.42 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) UPF0542 PF15086.1 CBK19660.2 - 0.12 12.0 0.7 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Pro_isomerase PF00160.16 CBK19662.2 - 1.5e-13 51.2 0.0 1.7e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetate_kinase PF00871.12 CBK19663.2 - 0.021 13.3 0.1 0.023 13.2 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family Vps52 PF04129.7 CBK19664.2 - 6.6e-15 54.6 2.3 8.2e-15 54.3 1.6 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DDRGK PF09756.4 CBK19665.2 - 2.4e-34 118.3 30.1 2.4e-34 118.3 20.9 1.9 2 0 0 2 2 2 1 DDRGK domain STN1_2 PF09170.5 CBK19665.2 - 0.0093 15.7 2.2 0.015 15.0 0.3 2.0 2 0 0 2 2 2 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 HTH_24 PF13412.1 CBK19665.2 - 0.015 14.7 0.6 1.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 CBK19665.2 - 0.016 14.7 0.3 0.67 9.5 0.0 2.7 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain HTH_40 PF14493.1 CBK19665.2 - 0.031 14.4 3.2 0.092 12.9 0.6 3.0 1 1 1 2 2 2 0 Helix-turn-helix domain FeoC PF09012.5 CBK19665.2 - 0.051 13.2 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator EF1_GNE PF00736.14 CBK19665.2 - 0.054 13.1 3.6 0.12 12.1 0.4 2.7 2 1 0 2 2 2 0 EF-1 guanine nucleotide exchange domain FumaraseC_C PF10415.4 CBK19665.2 - 0.11 12.5 0.2 16 5.6 0.0 3.6 4 0 0 4 4 4 0 Fumarase C C-terminus DUF3987 PF13148.1 CBK19665.2 - 3.3 6.1 17.1 6.1 5.3 11.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ORC6 PF05460.8 CBK19665.2 - 8.5 5.3 14.8 12 4.8 10.1 1.5 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RPN7 PF10602.4 CBK19666.2 - 6.8e-33 113.5 3.6 1.2e-32 112.7 2.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CBK19666.2 - 2.6e-12 46.9 0.6 1e-11 45.0 0.0 2.3 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.1 CBK19666.2 - 0.0001 22.1 0.1 0.00059 19.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK19666.2 - 0.00028 20.5 0.2 0.037 13.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK19666.2 - 0.00031 20.3 0.0 0.0065 16.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK19666.2 - 0.0022 17.5 0.6 0.039 13.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK19666.2 - 0.011 15.8 0.1 0.57 10.3 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBK19666.2 - 0.023 14.4 1.2 0.1 12.4 0.8 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK19666.2 - 0.041 14.3 0.3 0.31 11.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBK19666.2 - 0.13 11.9 0.2 0.75 9.4 0.2 2.3 1 1 0 1 1 1 0 TPR repeat DUF3887 PF13026.1 CBK19666.2 - 0.74 10.1 8.3 0.13 12.5 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) Ribosomal_L4 PF00573.17 CBK19667.2 - 1.2e-32 112.8 0.6 1.5e-32 112.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family GHL13 PF14883.1 CBK19667.2 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 CPSF_A PF03178.10 CBK19668.2 - 9e-85 284.5 0.0 2.9e-83 279.6 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 CBK19668.2 - 2.2e-53 181.1 0.0 3.7e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MCM PF00493.18 CBK19669.2 - 2.5e-130 434.1 0.1 3.3e-130 433.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBK19669.2 - 7e-06 25.3 0.0 7.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBK19669.2 - 0.00045 19.8 0.0 0.0026 17.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK19669.2 - 0.0027 17.4 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBK19669.2 - 0.087 12.2 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 CBK19670.2 - 2e-44 151.0 0.0 4.9e-44 149.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK19670.2 - 2.1e-24 85.1 0.2 1.6e-22 79.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK19670.2 - 0.00013 21.8 0.0 0.00097 19.0 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBK19670.2 - 0.00018 20.3 0.0 0.00029 19.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 CBK19670.2 - 0.013 14.7 0.0 0.41 9.9 0.0 2.4 2 1 0 2 2 2 0 SecA DEAD-like domain DUF1675 PF07897.6 CBK19671.2 - 0.088 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AAA PF00004.24 CBK19672.2 - 0.00018 21.7 0.1 0.00088 19.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PEX11 PF05648.9 CBK19674.2 - 0.028 13.6 0.3 0.051 12.8 0.2 1.5 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) He_PIG PF05345.7 CBK19675.2 - 9.8e-10 38.3 16.2 0.00065 19.6 0.7 4.0 3 0 0 3 3 3 3 Putative Ig domain Bac_rhamnosid PF05592.6 CBK19676.2 - 0.034 12.3 3.1 0.038 12.2 2.0 1.2 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DUF812 PF05667.6 CBK19676.2 - 0.42 9.0 22.5 0.71 8.3 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2580 PF10824.3 CBK19676.2 - 1.2 9.5 6.0 2 8.7 0.3 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2580) CENP-F_leu_zip PF10473.4 CBK19676.2 - 3 7.7 28.9 6.6 6.5 4.8 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CBK19676.2 - 3.4 7.2 23.0 1.2 8.7 3.8 3.4 2 1 1 3 3 3 0 Septum formation initiator SOBP PF15279.1 CBK19676.2 - 3.4 7.9 4.9 4 7.7 3.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Kinesin PF00225.18 CBK19677.2 - 2.4e-97 325.6 0.0 4.4e-97 324.7 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Rabaptin PF03528.10 CBK19677.2 - 0.018 14.9 0.7 0.057 13.3 0.5 1.8 1 1 0 1 1 1 0 Rabaptin DUF1192 PF06698.6 CBK19677.2 - 0.03 14.1 0.0 0.03 14.1 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) DUF3584 PF12128.3 CBK19677.2 - 0.041 11.2 0.1 0.052 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 CBK19677.2 - 0.097 12.4 0.4 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Lzipper-MIP1 PF14389.1 CBK19677.2 - 0.12 12.5 0.9 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 THOC7 PF05615.8 CBK19677.2 - 0.27 11.4 2.1 0.6 10.3 0.1 2.1 1 1 0 2 2 2 0 Tho complex subunit 7 ETF_alpha PF00766.14 CBK19678.2 - 2.5e-14 52.6 0.5 3.6e-14 52.1 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Kinesin PF00225.18 CBK19679.2 - 3.5e-32 111.4 0.0 3.5e-32 111.4 0.0 3.3 4 1 0 4 4 4 1 Kinesin motor domain Cep57_CLD_2 PF14197.1 CBK19679.2 - 8.3e-05 22.4 16.7 8.3e-05 22.4 11.6 8.1 7 3 1 8 8 8 2 Centrosome localisation domain of PPC89 Mitofilin PF09731.4 CBK19679.2 - 0.00067 18.4 17.1 0.00067 18.4 11.8 3.1 2 1 1 3 3 3 1 Mitochondrial inner membrane protein Rab5-bind PF09311.6 CBK19679.2 - 0.0076 16.1 8.5 0.0076 16.1 5.9 6.1 2 2 3 5 5 5 3 Rabaptin-like protein HALZ PF02183.13 CBK19679.2 - 0.14 11.8 67.5 0.095 12.4 1.1 8.9 7 2 0 8 8 8 0 Homeobox associated leucine zipper Mto2_bdg PF12808.2 CBK19679.2 - 2.7 8.1 65.1 0.21 11.7 3.2 7.5 5 1 1 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 CBK19679.2 - 3.1 6.8 19.3 0.24 10.5 2.6 3.8 3 1 1 4 4 4 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBK19679.2 - 3.3 7.5 123.8 0.31 10.8 16.6 6.2 3 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinesin PF00225.18 CBK19680.2 - 1.3e-36 125.9 0.7 1.5e-36 125.8 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain Thioredoxin_6 PF13848.1 CBK19681.2 - 4.3e-20 72.3 0.1 8.4e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBK19681.2 - 2.6e-17 62.4 0.0 1.8e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CBK19681.2 - 0.00015 21.8 0.2 0.03 14.4 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK19681.2 - 0.00053 20.1 0.4 0.025 14.7 0.2 3.1 3 1 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.1 CBK19681.2 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 CBK19681.2 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 CBK19681.2 - 0.031 14.3 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 CBK19681.2 - 0.035 14.0 0.1 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin ERp29_N PF07912.8 CBK19681.2 - 0.059 13.2 0.2 0.42 10.5 0.1 2.4 2 1 0 2 2 2 0 ERp29, N-terminal domain Ribosomal_S4 PF00163.14 CBK19682.2 - 3.6e-20 72.1 0.4 7.2e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBK19682.2 - 6.3e-13 47.9 0.4 6.3e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.7 CBK19682.2 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger CoA_binding PF02629.14 CBK19683.2 - 9.4e-29 99.7 1.3 9.4e-29 99.7 0.9 2.6 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBK19683.2 - 1.9e-23 82.7 0.1 3.8e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBK19683.2 - 2.2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK19683.2 - 5.2e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CBK19683.2 - 0.0042 17.6 0.1 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SseB PF07179.7 CBK19683.2 - 0.068 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 SseB protein N-terminal domain RRM_1 PF00076.17 CBK19684.2 - 1.7e-35 120.4 0.0 7.6e-17 60.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19684.2 - 5.1e-24 84.0 0.0 2.1e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19684.2 - 7.9e-15 54.4 0.2 3.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC27 PF09507.5 CBK19684.2 - 0.05 12.8 58.8 0.071 12.3 40.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nup35_RRM_2 PF14605.1 CBK19684.2 - 0.069 12.9 0.0 0.7 9.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Asp-B-Hydro_N PF05279.6 CBK19684.2 - 5.5 6.7 53.6 8.2 6.2 37.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L21e PF01157.13 CBK19685.2 - 1.1e-39 134.2 4.0 1.6e-39 133.6 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Put_Phosphatase PF06888.7 CBK19685.2 - 0.054 12.6 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase MSP1b PF03429.8 CBK19685.2 - 0.15 9.8 0.0 0.18 9.6 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B MFS_1 PF07690.11 CBK19688.2 - 5e-35 120.8 21.1 7.4e-35 120.2 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK19688.2 - 8.4e-10 37.8 16.0 1.2e-09 37.3 11.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Thioredoxin PF00085.15 CBK19690.2 - 1.1e-38 131.0 0.0 4.2e-20 71.3 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CBK19690.2 - 9.8e-30 103.7 0.1 7.4e-20 71.5 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK19690.2 - 2.4e-07 30.9 1.1 0.042 14.0 0.4 4.0 4 1 0 4 4 4 2 Thioredoxin-like domain ERp29_N PF07912.8 CBK19690.2 - 5.9e-05 23.0 0.3 0.015 15.2 0.0 3.7 4 1 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.1 CBK19690.2 - 0.00037 20.5 0.1 0.15 12.2 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBK19690.2 - 0.00084 19.3 0.1 0.025 14.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBK19690.2 - 0.0036 17.0 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.12 CBK19690.2 - 0.018 13.8 0.3 0.32 9.7 0.0 2.5 3 0 0 3 3 3 0 Calsequestrin Glutaredoxin PF00462.19 CBK19690.2 - 0.11 12.4 1.2 28 4.8 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin PAP2 PF01569.16 CBK19691.2 - 3.3e-22 78.5 0.4 4.4e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF3593 PF12159.3 CBK19691.2 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) ATP_synt_I PF03899.10 CBK19691.2 - 0.8 9.8 4.3 5.8 7.1 0.1 2.5 2 1 1 3 3 3 0 ATP synthase I chain CTD_bind PF04818.8 CBK19692.2 - 2.1e-08 34.2 0.2 1.4e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Serpentine_r_xa PF03383.10 CBK19692.2 - 0.052 13.2 0.9 0.085 12.6 0.6 1.3 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa IPK PF03770.11 CBK19693.2 - 1.8e-34 119.1 0.0 3e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase Transket_pyr PF02779.19 CBK19693.2 - 0.0098 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF2634 PF10934.3 CBK19693.2 - 0.011 15.4 0.2 0.017 14.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) WD40 PF00400.27 CBK19694.2 - 8.1e-36 120.6 4.1 5.7e-10 38.6 0.3 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK19694.2 - 5.6e-06 24.7 0.6 2.1e-05 22.8 0.2 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK19694.2 - 0.049 12.3 0.0 4.9 5.8 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like IL10 PF00726.12 CBK19696.2 - 0.001 18.3 0.1 0.033 13.4 0.0 2.6 3 0 0 3 3 3 2 Interleukin 10 SET PF00856.23 CBK19699.2 - 2.6e-19 70.1 0.9 5.8e-19 68.9 0.6 1.7 1 1 0 1 1 1 1 SET domain DnaJ PF00226.26 CBK19700.2 - 8.4e-27 92.6 1.1 9.7e-26 89.2 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.23 CBK19700.2 - 1.2e-06 27.8 1.6 2.1e-06 27.0 0.2 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK19700.2 - 3.7e-06 27.4 0.1 4.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK19700.2 - 4.2e-06 26.9 0.3 1.9e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK19700.2 - 8.2e-06 25.3 0.2 3.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBK19700.2 - 5.3e-05 22.8 0.5 0.00027 20.6 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK19700.2 - 0.00016 21.4 0.1 0.00037 20.3 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CBK19700.2 - 0.00019 20.9 0.2 0.00093 18.8 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK19700.2 - 0.00021 21.5 0.1 0.00058 20.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CBK19700.2 - 0.00053 19.2 0.5 0.00067 18.9 0.3 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.1 CBK19700.2 - 0.0019 18.0 0.1 0.014 15.3 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK19700.2 - 0.0029 17.2 0.1 0.02 14.6 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK19700.2 - 0.0093 16.3 1.0 0.087 13.3 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat YfdX PF10938.3 CBK19700.2 - 0.063 12.9 1.6 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 YfdX protein TPR_17 PF13431.1 CBK19700.2 - 0.1 12.8 0.1 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBK19700.2 - 0.15 12.0 2.9 0.29 11.0 0.1 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF1771 PF08590.5 CBK19700.2 - 1.4 8.9 5.8 0.4 10.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) Kelch_6 PF13964.1 CBK19701.2 - 0.083 13.1 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Kelch motif CIDE-N PF02017.10 CBK19701.2 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CIDE-N domain Ribosomal_S8e PF01201.17 CBK19702.2 - 2.8e-32 111.6 0.1 3.3e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Dynamin_M PF01031.15 CBK19703.2 - 8.1e-71 238.2 0.2 1.2e-70 237.6 0.1 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBK19703.2 - 9.4e-52 175.2 0.0 2.3e-51 173.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBK19703.2 - 0.0024 17.8 0.0 0.0068 16.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK19703.2 - 0.056 12.7 0.2 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 CBK19703.2 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 CBK19703.2 - 0.097 12.0 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain DUF4203 PF13886.1 CBK19704.2 - 8.9e-28 97.1 29.9 1e-27 96.9 20.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1191 PF06697.7 CBK19704.2 - 0.11 11.2 0.4 1.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1191) DUF3789 PF12664.2 CBK19704.2 - 3.1 7.1 9.4 1.3 8.4 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3789) FANCI_S4 PF14678.1 CBK19705.2 - 1.6e-27 96.2 2.5 2.7e-27 95.4 1.7 1.4 1 1 0 1 1 1 1 FANCI solenoid 4 Myb_DNA-bind_6 PF13921.1 CBK19706.2 - 1.8e-35 120.8 16.0 2.8e-14 52.9 0.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CBK19706.2 - 3.3e-35 119.9 14.7 1.8e-13 50.2 0.4 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CBK19706.2 - 0.015 15.1 5.2 0.67 9.8 0.1 3.1 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CBK19706.2 - 0.065 13.3 12.0 1.1 9.4 0.3 3.8 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Collagen PF01391.13 CBK19706.2 - 0.072 12.6 2.8 0.14 11.6 1.9 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) V-SNARE_C PF12352.3 CBK19707.2 - 2.2e-07 30.8 0.6 2.2e-07 30.8 0.4 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CBK19707.2 - 4.4e-07 29.9 2.2 4.4e-07 29.9 1.5 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Bcr-Abl_Oligo PF09036.5 CBK19707.2 - 0.0062 16.4 0.1 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain Sec20 PF03908.8 CBK19707.2 - 0.0098 15.5 6.0 0.015 14.9 0.1 3.2 1 1 1 3 3 3 1 Sec20 tRNA_NucTran2_2 PF13735.1 CBK19707.2 - 0.046 13.5 2.3 0.071 12.9 0.6 1.9 1 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Syntaxin-6_N PF09177.6 CBK19707.2 - 0.079 13.3 4.4 0.085 13.2 1.0 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spectrin PF00435.16 CBK19707.2 - 0.15 12.3 2.8 0.15 12.3 0.6 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF2408 PF10303.4 CBK19707.2 - 0.2 11.7 6.0 0.22 11.6 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.5 CBK19707.2 - 0.37 10.9 12.2 0.053 13.6 4.6 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 CBK19707.2 - 0.85 9.0 10.1 2.6 7.4 0.4 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Potass_KdpF PF09604.5 CBK19707.2 - 2 8.3 5.0 3.7 7.4 3.4 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Adenine_glyco PF03352.8 CBK19707.2 - 2.3 7.6 7.3 5 6.6 1.3 2.5 1 1 3 4 4 4 0 Methyladenine glycosylase Rifin_STEVOR PF02009.11 CBK19707.2 - 3.4 7.2 17.0 34 3.9 11.8 2.1 1 1 0 1 1 1 0 Rifin/stevor family CENP-Q PF13094.1 CBK19707.2 - 4.1 7.4 9.4 16 5.4 3.2 2.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SNARE PF05739.14 CBK19707.2 - 4.1 7.1 7.4 2.2 8.0 0.5 3.3 3 1 0 3 3 3 0 SNARE domain DUF2203 PF09969.4 CBK19707.2 - 5.2 7.3 7.9 1.6 8.9 1.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.20 CBK19707.2 - 7.4 6.7 12.8 12 6.1 4.4 3.2 1 1 1 2 2 2 0 Syntaxin FliJ PF02050.11 CBK19707.2 - 8.5 6.4 11.8 2.9 7.9 5.2 2.2 2 1 0 2 2 2 0 Flagellar FliJ protein AP_endonuc_2 PF01261.19 CBK19709.2 - 4.6e-28 97.9 0.0 6.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1899 PF08953.6 CBK19709.2 - 0.0051 16.4 0.2 1.2 8.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) XPG_I PF00867.13 CBK19710.2 - 7.2e-29 99.6 0.4 1.7e-28 98.4 0.3 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBK19710.2 - 3.5e-24 84.9 0.5 1e-23 83.5 0.1 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CBK19710.2 - 1.2e-06 28.6 0.5 1.1e-05 25.5 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 CBK19710.2 - 4e-05 23.0 0.1 0.00022 20.6 0.0 2.2 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DUF4192 PF13830.1 CBK19710.2 - 0.094 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Peptidase_C1 PF00112.18 CBK19711.2 - 1e-16 61.4 0.0 1.5e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease tRNA_NucTran2_2 PF13735.1 CBK19713.2 - 0.06 13.1 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.2 CBK19714.2 - 0.0015 18.0 0.2 0.0041 16.6 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Aa_trans PF01490.13 CBK19716.2 - 1.1e-21 76.7 18.9 1.4e-21 76.4 13.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBK19716.2 - 0.00033 19.5 15.6 0.00044 19.1 10.8 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family FUSC PF04632.7 CBK19716.2 - 0.1 11.0 4.9 0.17 10.3 3.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_hydro_20 PF00728.17 CBK19718.2 - 3.1e-71 240.3 0.0 3.8e-67 226.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain DEAD PF00270.24 CBK19718.2 - 4.3e-43 146.7 0.0 7.8e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.23 CBK19718.2 - 9.1e-26 90.3 0.4 1.9e-25 89.3 0.3 1.6 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 CBK19718.2 - 5.5e-22 77.4 0.0 1.1e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK19718.2 - 0.0012 18.6 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Glyco_hydro_97 PF10566.4 CBK19718.2 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 Hat1_N PF10394.4 CBK19719.2 - 9.7e-15 54.9 0.1 2e-14 53.9 0.0 1.5 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Glycohydro_20b2 PF14845.1 CBK19719.2 - 0.0023 18.6 0.5 0.013 16.2 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like zf-H2C2_2 PF13465.1 CBK19720.2 - 8.6e-07 28.9 6.3 8.6e-07 28.9 4.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CBK19720.2 - 6.8e-06 26.1 18.0 0.0062 16.8 4.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBK19720.2 - 1e-05 25.4 16.5 0.006 16.7 3.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBK19720.2 - 0.00013 22.0 16.4 0.032 14.5 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3505 PF12013.3 CBK19720.2 - 0.077 13.2 8.2 0.93 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) TGS PF02824.16 CBK19721.2 - 4.2e-23 80.9 0.0 8.1e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBK19721.2 - 3.4e-18 65.6 0.0 6.7e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK19721.2 - 7.9e-11 41.4 0.1 7.1e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBK19721.2 - 0.00055 19.8 0.2 0.11 12.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CBK19721.2 - 0.0039 15.9 0.1 0.0098 14.6 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CBK19721.2 - 0.0054 17.2 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein HSP70 PF00012.15 CBK19722.2 - 1.9e-46 158.2 14.4 3.9e-46 157.1 0.9 2.2 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK19722.2 - 1.4e-09 37.0 0.3 4.9e-08 31.9 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein DUF1786 PF08735.5 CBK19722.2 - 0.00096 18.3 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF1682 PF07946.9 CBK19723.2 - 0.31 9.8 15.8 0.34 9.7 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Gti1_Pac2 PF09729.4 CBK19723.2 - 0.37 10.6 3.2 0.42 10.4 2.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.9 CBK19723.2 - 1.9 6.4 10.9 1.9 6.4 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 CBK19723.2 - 2.3 6.3 8.4 2.4 6.2 5.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Herpes_DNAp_acc PF04929.7 CBK19723.2 - 9 5.1 8.1 9.1 5.1 5.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNB PF00773.14 CBK19725.2 - 1.5e-91 307.1 0.2 1.5e-91 307.1 0.1 1.6 2 0 0 2 2 2 1 RNB domain Aldo_ket_red PF00248.16 CBK19726.2 - 8.9e-67 224.8 0.0 1.7e-66 223.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 CBK19727.2 - 4.5e-65 217.9 1.1 5.7e-65 217.6 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK19727.2 - 1.3e-23 83.7 1.1 1.6e-23 83.4 0.3 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK19727.2 - 1.3e-18 66.7 0.4 1.7e-18 66.4 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK19727.2 - 2.3e-07 30.1 0.1 2.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBK19727.2 - 2.9e-07 30.1 0.4 9.8e-07 28.3 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBK19727.2 - 0.00058 19.1 0.3 0.00095 18.4 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBK19727.2 - 0.0007 19.7 0.1 0.0032 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CBK19727.2 - 0.0018 17.5 0.1 0.0072 15.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.15 CBK19727.2 - 0.0022 16.7 3.1 0.69 8.5 0.6 3.0 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.12 CBK19727.2 - 0.003 17.1 0.2 0.011 15.2 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CBK19727.2 - 0.016 14.8 0.9 0.016 14.8 0.6 1.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBK19727.2 - 0.017 14.8 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CBK19727.2 - 0.02 14.0 0.1 0.042 13.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MCM PF00493.18 CBK19727.2 - 0.037 12.8 0.3 0.1 11.3 0.0 1.7 1 1 0 1 1 1 0 MCM2/3/5 family YTH PF04146.10 CBK19727.2 - 0.05 13.1 0.0 0.075 12.6 0.0 1.3 1 1 0 1 1 1 0 YT521-B-like domain Oxidored_nitro PF00148.14 CBK19727.2 - 0.062 11.9 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ribosomal_S21e PF01249.13 CBK19728.2 - 1.4e-30 105.0 0.0 1.5e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CNTF PF01110.12 CBK19729.2 - 0.039 13.2 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 Ciliary neurotrophic factor DUF3631 PF12307.3 CBK19729.2 - 0.095 12.5 1.0 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) DUF2072 PF09845.4 CBK19729.2 - 0.12 12.3 0.4 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) ASCH PF04266.9 CBK19730.2 - 3.3e-14 53.1 0.0 7.9e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 ASCH domain Stc1 PF12898.2 CBK19730.2 - 0.0029 17.6 1.2 0.0055 16.7 0.8 1.4 1 0 0 1 1 1 1 Stc1 domain UPF0565 PF10561.4 CBK19731.2 - 1.1e-27 96.8 1.3 3.1e-16 59.1 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 DUF2846 PF11008.3 CBK19731.2 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) PGM_PMM_I PF02878.11 CBK19732.2 - 5.7e-34 116.5 0.0 1.1e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CBK19732.2 - 9.7e-21 74.0 0.0 2.3e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBK19732.2 - 6.6e-13 48.6 0.1 2.4e-12 46.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CBK19732.2 - 3.9e-07 29.9 0.0 1.1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1349 PF07081.6 CBK19733.2 - 2e-55 186.9 0.2 2.5e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Methyltransf_26 PF13659.1 CBK19734.2 - 1.2e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK19734.2 - 0.00013 22.5 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK19734.2 - 0.0041 16.5 0.0 0.0076 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBK19734.2 - 0.0094 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Trefoil PF00088.13 CBK19736.2 - 0.00014 21.4 3.5 0.00014 21.4 2.4 2.7 2 1 0 2 2 2 1 Trefoil (P-type) domain DUF1217 PF06748.7 CBK19736.2 - 0.18 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) IncA PF04156.9 CBK19737.2 - 7.7e-06 25.6 33.3 0.0044 16.6 10.6 2.3 1 1 1 2 2 2 2 IncA protein ECM11 PF15463.1 CBK19737.2 - 7.8e-06 26.2 14.1 1.2e-05 25.5 9.8 1.4 1 0 0 1 1 1 1 Extracellular mutant protein 11 Reo_sigmaC PF04582.7 CBK19737.2 - 0.00022 20.5 2.3 0.00032 19.9 1.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Taxilin PF09728.4 CBK19737.2 - 0.00029 20.0 34.5 0.0031 16.6 11.2 2.2 1 1 1 2 2 2 2 Myosin-like coiled-coil protein ATG16 PF08614.6 CBK19737.2 - 0.00071 19.4 29.0 0.00073 19.4 14.0 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 CBK19737.2 - 0.0036 17.4 14.8 0.0036 17.4 10.2 2.1 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family DivIC PF04977.10 CBK19737.2 - 0.0058 16.0 4.7 0.0058 16.0 3.2 4.1 1 1 2 4 4 4 1 Septum formation initiator DUF641 PF04859.7 CBK19737.2 - 0.012 15.4 22.5 0.014 15.1 7.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Bacillus_HBL PF05791.6 CBK19737.2 - 0.019 14.3 16.7 0.12 11.6 3.1 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CBK19737.2 - 0.022 13.2 26.2 0.029 12.8 18.1 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 CBK19737.2 - 0.051 13.3 16.8 0.028 14.2 5.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.16 CBK19737.2 - 0.079 12.4 30.1 0.63 9.4 9.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein Sipho_Gp157 PF05565.6 CBK19737.2 - 0.13 11.8 23.4 0.091 12.3 9.4 2.5 1 1 2 3 3 3 0 Siphovirus Gp157 Spectrin PF00435.16 CBK19737.2 - 0.2 11.9 21.9 1 9.6 7.0 2.6 1 1 1 2 2 2 0 Spectrin repeat Seryl_tRNA_N PF02403.17 CBK19737.2 - 0.21 11.6 27.7 0.46 10.5 3.5 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 CBK19737.2 - 0.27 8.4 27.3 0.037 11.3 10.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.4 CBK19737.2 - 0.42 10.7 24.6 0.55 10.3 8.6 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THP2 PF09432.5 CBK19737.2 - 0.44 10.4 17.0 0.54 10.1 1.0 2.1 1 1 0 2 2 2 0 Tho complex subunit THP2 FAD-SLDH PF12318.3 CBK19737.2 - 0.45 10.1 6.2 0.69 9.5 0.6 2.3 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Laminin_II PF06009.7 CBK19737.2 - 0.45 10.2 19.8 0.019 14.6 6.0 2.2 2 0 0 2 2 2 0 Laminin Domain II WXG100 PF06013.7 CBK19737.2 - 0.46 10.5 8.8 0.73 9.8 1.8 3.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG FadA PF09403.5 CBK19737.2 - 0.52 10.3 28.5 0.41 10.6 6.4 3.9 1 1 2 3 3 3 0 Adhesion protein FadA DUF4200 PF13863.1 CBK19737.2 - 0.52 10.2 36.0 0.045 13.7 5.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 CBK19737.2 - 0.54 10.5 0.1 0.54 10.5 0.1 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TarH PF02203.10 CBK19737.2 - 0.6 9.9 15.1 5.6 6.7 2.5 2.3 1 1 1 2 2 2 0 Tar ligand binding domain homologue CCDC155 PF14662.1 CBK19737.2 - 0.61 9.6 32.2 2.3 7.7 21.7 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF948 PF06103.6 CBK19737.2 - 0.73 9.7 15.7 1.7 8.5 1.3 3.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Mitovir_RNA_pol PF05919.6 CBK19737.2 - 0.98 8.2 9.4 1.2 7.9 6.5 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase DUF812 PF05667.6 CBK19737.2 - 1 7.7 27.4 8.1 4.8 18.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 CBK19737.2 - 1.1 9.6 28.7 3 8.2 3.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2680 PF10925.3 CBK19737.2 - 1.1 9.1 0.1 1.1 9.1 0.0 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF2680) GAS PF13851.1 CBK19737.2 - 1.2 8.3 34.2 2.6 7.2 11.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF664 PF04978.7 CBK19737.2 - 1.3 9.2 5.8 3.4 7.8 0.5 3.1 1 1 2 3 3 2 0 Protein of unknown function (DUF664) TEX12 PF15219.1 CBK19737.2 - 1.5 8.8 9.8 0.24 11.4 1.9 2.4 1 1 1 2 2 2 0 Testis-expressed 12 Ribosomal_S6 PF01250.12 CBK19737.2 - 1.7 8.5 9.3 1.5 8.7 1.1 3.0 1 1 1 2 2 2 0 Ribosomal protein S6 AAA_27 PF13514.1 CBK19737.2 - 2.3 5.7 25.1 3.1 5.3 17.4 1.1 1 0 0 1 1 1 0 AAA domain Lebercilin PF15619.1 CBK19737.2 - 3.1 7.1 32.7 1.9 7.8 17.6 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 CBK19737.2 - 3.3 7.6 31.1 0.27 11.1 7.2 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding T2SF PF00482.18 CBK19737.2 - 3.8 7.4 7.6 1.1 9.2 1.2 2.5 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F PEARLI-4 PF05278.7 CBK19737.2 - 3.9 6.7 20.9 4.5 6.5 14.0 1.5 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF148 PF02520.12 CBK19737.2 - 4 7.2 17.8 0.64 9.8 5.9 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF2205 PF10224.4 CBK19737.2 - 4.4 6.9 23.9 0.38 10.3 1.4 3.6 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF724 PF05266.9 CBK19737.2 - 5.2 6.6 28.9 0.24 11.0 13.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_I PF06008.9 CBK19737.2 - 5.6 6.2 28.8 5.4 6.2 4.0 2.8 1 1 1 2 2 2 0 Laminin Domain I SlyX PF04102.7 CBK19737.2 - 8.6 6.8 23.6 0.24 11.8 1.2 4.1 1 1 3 4 4 4 0 SlyX Atg14 PF10186.4 CBK19737.2 - 9 5.1 28.8 65 2.3 20.0 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2265 PF10023.4 CBK19737.2 - 9.5 5.2 15.9 3.2 6.7 5.2 2.0 1 1 1 2 2 2 0 Predicted aminopeptidase (DUF2265) ARD PF03079.9 CBK19737.2 - 9.6 6.1 14.6 0.61 10.0 3.9 2.4 1 1 1 2 2 2 0 ARD/ARD' family DUF914 PF06027.7 CBK19738.2 - 2.2e-67 227.2 22.3 2.8e-67 226.9 15.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CBK19738.2 - 2.4e-09 36.5 23.0 3.2e-09 36.1 15.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBK19738.2 - 2.1e-08 34.2 27.7 0.00029 20.8 5.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBK19738.2 - 5.8e-08 32.5 25.2 5.1e-06 26.2 7.6 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBK19738.2 - 6.4e-08 32.7 22.9 8.1e-07 29.2 4.4 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Mg_trans_NIPA PF05653.9 CBK19738.2 - 3.4e-05 22.9 5.1 3.4e-05 22.9 3.6 2.3 1 1 1 2 2 2 1 Magnesium transporter NIPA Nuc_sug_transp PF04142.10 CBK19738.2 - 0.11 11.5 18.3 0.037 13.1 10.3 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter UPF0546 PF10639.4 CBK19738.2 - 0.14 11.9 6.9 1.5 8.6 0.1 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 RINGv PF12906.2 CBK19739.2 - 0.035 14.1 0.5 0.058 13.4 0.4 1.4 1 0 0 1 1 1 0 RING-variant domain WD40 PF00400.27 CBK19740.2 - 3e-12 45.9 9.1 9.6e-07 28.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Pyr_redox_2 PF07992.9 CBK19741.2 - 2.4e-36 125.5 0.0 2.6e-35 122.1 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBK19741.2 - 3.1e-19 69.1 8.0 1.2e-18 67.2 0.6 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK19741.2 - 1.6e-10 41.3 0.0 7.3e-06 26.1 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBK19741.2 - 2.4e-09 36.5 1.1 0.00081 18.3 0.1 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_dim PF02852.17 CBK19741.2 - 4.2e-09 36.4 0.0 1.2e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.1 CBK19741.2 - 3.1e-08 33.5 0.2 0.0013 18.6 0.0 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBK19741.2 - 9.1e-07 27.6 4.5 0.0039 15.7 0.0 3.8 3 1 1 4 4 4 2 HI0933-like protein Rhodanese PF00581.15 CBK19741.2 - 9.7e-06 25.9 0.0 9.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Lycopene_cycl PF05834.7 CBK19741.2 - 2.9e-05 23.1 2.4 0.57 9.0 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 CBK19741.2 - 6.3e-05 23.1 0.5 0.052 13.8 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 CBK19741.2 - 0.0002 21.1 1.7 7.1 6.3 0.1 4.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CBK19741.2 - 0.0003 20.5 0.1 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 CBK19741.2 - 0.0011 17.9 0.1 0.0027 16.7 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 CBK19741.2 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 CBK19741.2 - 0.002 18.1 0.2 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.19 CBK19741.2 - 0.0048 15.7 0.6 0.58 8.9 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.19 CBK19741.2 - 0.0066 15.5 0.9 1.2 8.1 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.10 CBK19741.2 - 0.0083 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CBK19741.2 - 0.01 15.8 0.2 0.04 13.9 0.0 2.1 3 0 0 3 3 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 CBK19741.2 - 0.019 14.5 1.4 0.022 14.3 0.0 1.7 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CBK19741.2 - 0.028 14.4 0.8 0.065 13.3 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CBK19741.2 - 0.029 13.4 0.1 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 CBK19741.2 - 0.041 13.3 0.1 0.76 9.2 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 CBK19741.2 - 0.054 12.8 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 CBK19741.2 - 0.072 12.9 0.7 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBK19741.2 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_pol_E_B PF04042.11 CBK19742.2 - 1.8e-06 27.3 0.0 2.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.11 CBK19744.2 - 1.4e-21 76.5 25.0 1.4e-12 47.0 1.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 CBK19744.2 - 5.7e-15 55.1 7.0 5.7e-15 55.1 4.8 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_2 PF13347.1 CBK19744.2 - 3.6e-06 25.6 26.7 0.0039 15.6 0.1 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein Cytochrom_B561 PF03188.11 CBK19744.2 - 0.0081 15.9 0.3 0.0081 15.9 0.2 3.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 TRADD_N PF09034.5 CBK19745.2 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain RRM_1 PF00076.17 CBK19746.2 - 9.2e-18 63.6 0.0 1.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19746.2 - 4.5e-14 52.1 0.0 7.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19746.2 - 1.8e-13 50.0 0.0 2.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CBK19746.2 - 0.00083 19.1 3.8 0.0013 18.5 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CBK19746.2 - 0.0059 16.2 1.8 0.007 16.0 0.1 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CBK19746.2 - 0.03 14.0 2.1 0.053 13.2 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Viral_NABP PF05515.6 CBK19746.2 - 0.061 13.5 0.1 0.081 13.1 0.1 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding DUF1866 PF08952.6 CBK19746.2 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 CBK19746.2 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PWI PF01480.12 CBK19747.2 - 1.1e-22 79.9 1.8 2.3e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 PWI domain ISN1 PF06437.6 CBK19747.2 - 0.11 11.2 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase ABC_tran PF00005.22 CBK19748.2 - 3.1e-47 160.3 1.2 1.4e-23 83.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CBK19748.2 - 9.7e-19 68.4 4.5 1.7e-05 24.9 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 CBK19748.2 - 1.1e-13 50.9 1.3 1.3e-05 24.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBK19748.2 - 7.7e-09 34.9 0.2 0.0038 16.7 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 CBK19748.2 - 3.7e-08 32.7 0.0 0.0028 16.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran_2 PF12848.2 CBK19748.2 - 3.1e-07 30.1 3.6 3.1e-07 30.1 2.5 2.7 4 0 0 4 4 2 1 ABC transporter AAA_16 PF13191.1 CBK19748.2 - 4.2e-06 26.8 0.5 0.069 13.1 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 CBK19748.2 - 5.8e-06 26.7 0.2 0.009 16.5 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 CBK19748.2 - 1.1e-05 25.6 0.6 0.61 10.2 0.2 4.2 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CBK19748.2 - 1.5e-05 24.4 0.0 0.075 12.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 CBK19748.2 - 2.5e-05 24.1 0.2 0.011 15.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBK19748.2 - 2.8e-05 23.3 8.8 0.08 11.9 0.0 4.6 4 1 0 5 5 5 2 AAA ATPase domain NACHT PF05729.7 CBK19748.2 - 5.8e-05 22.7 0.0 0.39 10.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 CBK19748.2 - 9.9e-05 22.4 0.0 0.57 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase FlxA PF14282.1 CBK19748.2 - 0.00026 20.9 7.7 0.0016 18.3 0.6 2.5 2 0 0 2 2 2 1 FlxA-like protein MMR_HSR1 PF01926.18 CBK19748.2 - 0.00074 19.4 1.6 0.15 12.0 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CBK19748.2 - 0.00076 20.2 5.0 0.27 12.0 0.0 3.8 4 1 0 4 4 3 1 AAA domain ArgK PF03308.11 CBK19748.2 - 0.00081 18.2 0.1 0.3 9.8 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 CBK19748.2 - 0.0012 19.1 3.3 1.9 8.7 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 CBK19748.2 - 0.0014 18.3 0.5 1.2 8.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CBK19748.2 - 0.0018 18.1 10.2 0.39 10.5 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function DUF87 AAA_14 PF13173.1 CBK19748.2 - 0.0021 17.9 0.1 11 5.9 0.0 3.8 3 1 0 3 3 3 0 AAA domain MobB PF03205.9 CBK19748.2 - 0.0043 16.7 0.0 0.85 9.3 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CBK19748.2 - 0.0059 15.4 0.1 0.17 10.6 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 CBK19748.2 - 0.0073 16.1 0.4 3.9 7.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 CBK19748.2 - 0.01 15.5 0.1 3.2 7.4 0.0 2.9 3 0 0 3 3 2 0 NTPase SRP54 PF00448.17 CBK19748.2 - 0.01 15.2 0.0 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CBK19748.2 - 0.013 15.1 0.1 0.95 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBK19748.2 - 0.014 15.5 3.9 6 7.0 0.0 4.0 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBK19748.2 - 0.016 15.2 0.4 4.1 7.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Seryl_tRNA_N PF02403.17 CBK19748.2 - 0.016 15.1 3.2 0.016 15.1 2.2 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain AAA_10 PF12846.2 CBK19748.2 - 0.057 12.8 6.8 2.2 7.6 0.2 4.1 4 2 1 5 5 5 0 AAA-like domain OmpH PF03938.9 CBK19748.2 - 0.057 13.3 6.6 0.63 9.9 2.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MRP-L28 PF09812.4 CBK19748.2 - 0.084 12.6 2.4 0.26 11.1 1.7 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 AAA_23 PF13476.1 CBK19748.2 - 0.31 11.3 22.0 0.55 10.5 0.0 4.4 4 1 0 5 5 4 0 AAA domain MerR-DNA-bind PF09278.6 CBK19748.2 - 0.35 11.2 9.3 0.17 12.3 3.1 2.5 2 0 0 2 2 2 0 MerR, DNA binding Mnd1 PF03962.10 CBK19748.2 - 3.4 7.2 9.6 0.69 9.5 1.2 3.1 3 0 0 3 3 3 0 Mnd1 family eIF-4B PF06273.6 CBK19748.2 - 7.1 5.2 8.5 8 5.0 1.6 2.2 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B IncA PF04156.9 CBK19748.2 - 7.1 6.1 11.5 2.9 7.4 1.5 2.3 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 CBK19748.2 - 7.3 5.4 8.9 3.1 6.6 0.7 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FtsK_SpoIIIE PF01580.13 CBK19748.2 - 8.6 5.7 8.0 9.7 5.5 0.0 3.2 4 0 0 4 4 3 0 FtsK/SpoIIIE family HSP70 PF00012.15 CBK19749.2 - 1.4e-268 891.8 12.3 1.6e-268 891.6 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK19749.2 - 1e-14 53.9 1.6 2.5e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK19749.2 - 1.5e-05 24.8 3.0 0.0081 15.9 0.2 4.3 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 CBK19749.2 - 0.0011 18.6 0.0 0.0034 17.0 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CBK19749.2 - 0.0038 16.5 0.0 0.12 11.6 0.0 2.7 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family PEP-utilisers_N PF05524.8 CBK19749.2 - 0.58 9.9 6.2 1.8 8.3 0.0 3.4 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal CRAL_TRIO PF00650.15 CBK19750.2 - 2.5e-11 43.3 0.1 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain PH PF00169.24 CBK19750.2 - 0.0047 17.1 1.4 0.0085 16.2 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 CBK19750.2 - 0.0091 16.2 1.4 0.017 15.3 1.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4327 PF14217.1 CBK19750.2 - 0.11 12.3 0.2 0.53 10.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4327) Melibiase PF02065.13 CBK19751.2 - 1.4e-21 76.7 1.2 8.1e-16 57.6 0.0 2.3 2 1 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 CBK19751.2 - 0.031 13.3 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 PAP_central PF04928.12 CBK19752.2 - 1.3e-46 158.4 0.2 1.3e-45 155.2 0.1 2.0 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBK19752.2 - 4.2e-20 71.8 0.0 7.5e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBK19752.2 - 0.00025 21.2 0.0 0.00093 19.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain RRM_1 PF00076.17 CBK19753.2 - 2.2e-18 65.6 0.2 3.6e-16 58.5 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19753.2 - 4.8e-15 55.2 0.1 1.8e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19753.2 - 2.5e-05 24.0 0.1 3.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 CBK19754.2 - 1.3e-59 200.2 0.0 1.7e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK19754.2 - 2.4e-22 79.6 0.0 3.8e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK19754.2 - 2.1e-14 53.1 0.1 2.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBK19754.2 - 9e-08 31.5 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBK19754.2 - 1.6e-05 24.4 0.0 6.7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK19754.2 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK19754.2 - 3.1e-05 23.2 0.1 3.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBK19754.2 - 0.00076 19.6 0.0 0.014 15.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 CBK19754.2 - 0.0023 17.2 0.2 0.084 12.1 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.1 CBK19754.2 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CBK19754.2 - 0.023 14.2 0.1 0.65 9.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 CBK19754.2 - 0.026 14.7 0.1 0.2 11.8 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK19754.2 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CBK19754.2 - 0.074 12.9 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBK19754.2 - 0.076 12.4 0.1 7.5 5.9 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CBK19754.2 - 0.078 12.1 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CBK19754.2 - 0.12 12.1 0.0 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Got1 PF04178.7 CBK19755.2 - 7.8e-12 45.3 12.0 9.1e-12 45.1 8.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 CBK19755.2 - 0.00063 19.6 4.1 0.00063 19.6 2.8 2.4 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) INT_SG_DDX_CT_C PF15300.1 CBK19755.2 - 0.043 13.2 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF373 PF04123.8 CBK19755.2 - 0.31 10.0 3.5 0.19 10.7 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CD20 PF04103.10 CBK19755.2 - 1.8 8.5 9.3 0.23 11.3 3.4 1.8 2 0 0 2 2 2 0 CD20-like family DUF2892 PF11127.3 CBK19755.2 - 7.2 6.5 8.6 2.6 7.9 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Prefoldin_2 PF01920.15 CBK19756.2 - 1.9e-12 46.8 4.4 2.3e-12 46.6 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4200 PF13863.1 CBK19756.2 - 0.11 12.4 2.7 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 CBK19756.2 - 0.12 12.0 3.3 9.5 5.8 2.3 2.1 1 1 0 1 1 1 0 Prefoldin subunit THOC7 PF05615.8 CBK19756.2 - 0.26 11.5 4.2 0.67 10.2 2.9 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Ribosomal_S25 PF03297.10 CBK19757.2 - 4.9e-20 71.5 0.3 6.1e-20 71.2 0.2 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Rhodanese PF00581.15 CBK19758.2 - 8.3e-25 87.3 0.0 7.3e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain WD40 PF00400.27 CBK19759.2 - 0.0081 16.0 0.7 4.1 7.4 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DSHCT PF08148.7 CBK19760.2 - 8.7e-43 145.6 0.6 1.6e-42 144.7 0.0 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CBK19760.2 - 6.9e-20 71.2 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK19760.2 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain VWA PF00092.23 CBK19761.2 - 9.5e-26 90.5 1.7 2e-25 89.5 1.2 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBK19761.2 - 1.5e-22 80.5 0.2 2.1e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBK19761.2 - 3.4e-07 30.0 0.0 9.7e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain TIG PF01833.19 CBK19761.2 - 2.3e-05 24.3 0.0 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain Anth_Ig PF05587.8 CBK19761.2 - 0.034 13.9 0.0 0.14 12.0 0.0 2.0 1 1 0 1 1 1 0 Anthrax receptor extracellular domain VWA_CoxE PF05762.9 CBK19761.2 - 0.046 12.8 0.2 0.077 12.1 0.2 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein ICMT PF04140.9 CBK19761.2 - 0.22 11.7 1.4 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ribosomal_L15e PF00827.12 CBK19762.2 - 4.1e-80 267.8 10.5 5.7e-79 264.0 7.3 1.9 1 1 0 1 1 1 1 Ribosomal L15 DUF1647 PF07801.6 CBK19763.2 - 0.048 13.1 1.1 0.22 11.0 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) Ribosomal_L22 PF00237.14 CBK19764.2 - 1.1e-28 99.2 0.1 1.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e POR_N PF01855.14 CBK19766.2 - 1.4e-57 194.9 0.1 2.7e-57 193.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK19766.2 - 2.9e-25 89.1 1.7 3.3e-25 88.9 0.2 1.9 2 0 0 2 2 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 CBK19766.2 - 6.8e-13 47.9 0.0 1.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function Fer4_7 PF12838.2 CBK19766.2 - 3.8e-09 36.7 6.8 3.8e-09 36.7 4.7 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK19766.2 - 1e-08 35.3 5.9 0.00019 21.6 1.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 CBK19766.2 - 1.8e-08 34.1 0.4 5.9e-08 32.4 0.3 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.1 CBK19766.2 - 2.3e-07 30.4 10.4 1.1e-05 25.0 7.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 CBK19766.2 - 2.5e-07 29.9 19.2 8.9e-05 21.9 1.0 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.1 CBK19766.2 - 1.7e-06 28.6 8.6 2.2e-05 25.1 5.9 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 CBK19766.2 - 5.4e-06 26.3 10.8 6.6e-06 26.0 6.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK19766.2 - 2.7e-05 23.8 16.6 0.0026 17.5 1.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.1 CBK19766.2 - 2.9e-05 23.8 14.2 0.00049 19.8 9.9 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK19766.2 - 0.00035 20.9 9.4 0.036 14.4 0.6 3.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK19766.2 - 0.00093 18.9 19.8 0.01 15.6 1.6 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBK19766.2 - 0.0013 19.0 11.1 0.0037 17.5 6.7 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK19766.2 - 0.024 14.5 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fer4_4 PF12800.2 CBK19766.2 - 0.025 14.8 20.1 0.027 14.7 2.8 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.1 CBK19766.2 - 0.06 13.7 10.4 0.33 11.3 0.7 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 CBK19766.2 - 0.26 11.8 8.7 2.8 8.5 0.2 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain Collagen PF01391.13 CBK19768.2 - 0.00083 18.8 2.6 0.0016 17.9 1.8 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Med3 PF11593.3 CBK19768.2 - 2 7.5 30.4 2.9e+02 0.4 21.0 2.2 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Fcf2 PF08698.6 CBK19769.2 - 1.5e-18 66.6 0.2 3.1e-18 65.5 0.1 1.5 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing AMP-binding PF00501.23 CBK19770.2 - 1.9e-67 227.4 0.0 2.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UQ_con PF00179.21 CBK19771.2 - 1.1e-13 50.7 0.7 1.7e-13 50.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SopD PF11047.3 CBK19771.2 - 0.0086 15.0 0.1 0.01 14.8 0.1 1.1 1 0 0 1 1 1 1 Salmonella outer protein D BTB PF00651.26 CBK19772.2 - 2.3e-06 27.5 0.2 3.3e-06 27.0 0.2 1.3 1 1 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 CBK19772.2 - 0.00041 20.3 0.4 0.00091 19.2 0.3 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Cystatin PF00031.16 CBK19773.2 - 1.8e-05 24.7 0.0 2.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain DUF1478 PF07349.6 CBK19774.2 - 0.062 12.6 0.3 0.062 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) Chorein_N PF12624.2 CBK19775.2 - 1.3e-14 53.7 2.0 1.6e-14 53.4 1.4 1.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter mIF3 PF14877.1 CBK19775.2 - 0.047 13.0 0.4 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial translation initiation factor DUF3996 PF13161.1 CBK19775.2 - 0.16 11.5 1.8 0.22 11.1 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3996) NifU PF01106.12 CBK19776.2 - 0.0049 16.6 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain SGT1 PF07093.6 CBK19776.2 - 0.019 13.3 0.6 0.019 13.3 0.4 1.0 1 0 0 1 1 1 0 SGT1 protein LUC7 PF03194.10 CBK19776.2 - 0.026 14.0 2.5 0.028 13.9 1.7 1.1 1 0 0 1 1 1 0 LUC7 N_terminus eIF-6 PF01912.13 CBK19777.2 - 2.5e-76 255.1 0.8 5e-76 254.2 0.6 1.5 1 0 0 1 1 1 1 eIF-6 family ApbA PF02558.11 CBK19777.2 - 1.4e-21 76.5 0.0 4.6e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CBK19777.2 - 2.5e-18 66.2 0.1 5.1e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Mso1_C PF14477.1 CBK19778.2 - 3.4 8.0 7.1 6.9 7.0 2.2 2.7 2 1 0 2 2 2 0 Membrane-polarising domain of Mso1 CH PF00307.26 CBK19779.2 - 0.002 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain HSP70 PF00012.15 CBK19781.2 - 6e-62 209.4 0.0 6.9e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK19781.2 - 5e-15 54.9 0.0 1.1e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 CBK19781.2 - 6.9e-05 21.8 0.1 0.18 10.5 0.0 2.5 2 1 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.3 CBK19781.2 - 0.00063 18.7 0.0 0.03 13.2 0.0 2.1 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.13 CBK19781.2 - 0.04 13.0 0.1 0.21 10.6 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Actin PF00022.14 CBK19781.2 - 0.099 11.0 0.0 1.7 6.9 0.0 2.1 1 1 0 1 1 1 0 Actin MutL PF13941.1 CBK19781.2 - 0.1 10.9 0.1 0.23 9.7 0.0 1.5 2 0 0 2 2 2 0 MutL protein Carboxyl_trans PF01039.17 CBK19782.2 - 6.8e-191 634.8 0.1 8.1e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK19782.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) MSC PF09402.5 CBK19783.2 - 1.6e-12 46.8 4.5 2.8e-12 45.9 3.1 1.3 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain TIL PF01826.12 CBK19783.2 - 0.024 14.7 5.8 0.059 13.4 4.0 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain TEX19 PF15553.1 CBK19783.2 - 0.035 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 cEGF PF12662.2 CBK19783.2 - 0.039 13.5 0.5 0.039 13.5 0.4 2.5 2 0 0 2 2 2 0 Complement Clr-like EGF-like EB PF01683.13 CBK19783.2 - 0.098 12.7 7.9 0.25 11.4 5.5 1.7 1 0 0 1 1 1 0 EB module Tme5_EGF_like PF09064.5 CBK19783.2 - 0.12 12.0 8.8 0.86 9.2 0.7 2.5 1 1 1 2 2 2 0 Thrombomodulin like fifth domain, EGF-like ARID PF01388.16 CBK19784.2 - 2.3e-16 59.4 0.0 4.6e-16 58.4 0.0 1.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-CW PF07496.10 CBK19784.2 - 6.1e-11 41.8 1.0 6.1e-11 41.8 0.7 1.6 2 0 0 2 2 2 1 CW-type Zinc Finger TFIIS_C PF01096.13 CBK19784.2 - 0.19 11.3 1.2 0.53 9.9 0.8 1.7 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Ribosomal_L13e PF01294.13 CBK19785.2 - 4.6e-72 241.2 2.0 6.1e-72 240.8 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e WD40 PF00400.27 CBK19786.2 - 1.5e-07 31.0 0.0 3.2e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat HSP70 PF00012.15 CBK19787.2 - 1.4e-100 336.9 3.1 1.5e-99 333.5 2.1 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK19787.2 - 3.4e-11 42.3 0.0 1.2e-10 40.4 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CBK19787.2 - 6.9e-05 22.5 0.1 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CBK19787.2 - 0.0062 16.3 0.4 4.4 7.1 0.0 3.3 2 1 0 2 2 2 2 Cell division protein FtsA ABC_tran PF00005.22 CBK19788.2 - 4e-49 166.4 0.0 3.4e-28 98.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK19788.2 - 1.9e-38 132.4 30.2 1.1e-19 70.8 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBK19788.2 - 3.9e-07 29.5 3.5 0.0081 15.4 0.0 4.0 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBK19788.2 - 3.4e-06 26.5 0.4 0.0035 16.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CBK19788.2 - 2.1e-05 24.9 0.5 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 CBK19788.2 - 3.6e-05 23.1 0.1 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 CBK19788.2 - 0.00016 21.5 0.3 0.05 13.4 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_23 PF13476.1 CBK19788.2 - 0.00018 21.9 0.1 0.085 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBK19788.2 - 0.0003 20.7 0.7 0.59 10.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 CBK19788.2 - 0.00063 19.8 0.0 2.7 7.8 0.0 3.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 CBK19788.2 - 0.0012 18.7 0.0 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CBK19788.2 - 0.0022 18.0 0.4 0.66 9.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 CBK19788.2 - 0.0033 16.3 0.0 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 CBK19788.2 - 0.005 17.6 0.9 0.86 10.4 0.2 2.7 2 1 0 2 2 2 1 AAA domain Chordopox_A13L PF05961.6 CBK19788.2 - 0.006 16.4 0.5 0.34 10.8 0.0 3.1 2 0 0 2 2 2 1 Chordopoxvirus A13L protein AAA_10 PF12846.2 CBK19788.2 - 0.0064 15.9 2.8 6.5 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CBK19788.2 - 0.0084 15.6 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 CBK19788.2 - 0.012 14.7 0.3 2.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 CBK19788.2 - 0.013 15.3 4.8 0.84 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 CBK19788.2 - 0.015 15.4 1.7 2.8 8.0 0.0 3.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBK19788.2 - 0.022 14.9 0.7 1.4 9.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBK19788.2 - 0.031 14.4 1.1 3.7 7.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ArgK PF03308.11 CBK19788.2 - 0.037 12.7 2.0 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 CBK19788.2 - 0.056 12.5 2.3 5.6 5.9 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 CBK19788.2 - 0.066 12.7 0.6 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 CBK19788.2 - 0.11 12.1 3.3 0.12 12.0 0.1 2.5 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 CBK19788.2 - 0.11 12.0 4.3 1.2 8.7 0.1 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 CBK19788.2 - 0.12 11.8 0.0 8.9 5.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 CBK19788.2 - 0.16 11.0 0.5 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC KAP_NTPase PF07693.9 CBK19788.2 - 0.17 10.8 0.0 0.63 8.9 0.0 1.9 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 CBK19788.2 - 0.2 11.9 0.7 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 CBK19788.2 - 0.22 10.3 1.2 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.9 CBK19788.2 - 0.25 11.0 1.7 8.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CBK19788.2 - 0.38 10.1 3.4 23 4.3 0.1 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein NTPase_1 PF03266.10 CBK19788.2 - 0.94 9.1 4.1 15 5.2 0.1 3.8 4 0 0 4 4 4 0 NTPase RseC_MucC PF04246.7 CBK19788.2 - 6.1 6.4 7.8 0.56 9.7 1.5 2.2 2 0 0 2 2 1 0 Positive regulator of sigma(E), RseC/MucC DUF3334 PF11813.3 CBK19789.2 - 0.046 13.2 2.0 0.063 12.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Daxx PF03344.10 CBK19789.2 - 0.66 8.3 16.4 0.81 8.0 11.4 1.1 1 0 0 1 1 1 0 Daxx Family Prog_receptor PF02161.10 CBK19789.2 - 1.4 7.6 8.0 1.7 7.3 5.5 1.1 1 0 0 1 1 1 0 Progesterone receptor CDC45 PF02724.9 CBK19789.2 - 2.6 5.9 10.0 3 5.7 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 CBK19789.2 - 4.8 6.2 8.5 8.8 5.4 5.9 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nop14 PF04147.7 CBK19789.2 - 6.2 4.6 17.4 7.7 4.3 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CBK19789.2 - 8.1 5.5 15.1 10 5.2 10.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIS_M PF07500.9 CBK19790.2 - 9.7e-24 83.6 1.8 1.6e-23 82.9 1.3 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RRM_1 PF00076.17 CBK19792.2 - 1.5e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19792.2 - 0.00033 20.4 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19792.2 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CBK19793.2 - 1.3e-42 145.7 0.3 2.9e-25 88.8 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK19793.2 - 3.2e-18 65.7 0.0 3.6e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBK19793.2 - 0.00021 20.3 0.0 0.094 11.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.15 CBK19793.2 - 0.0025 17.4 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CBK19793.2 - 0.0064 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK19793.2 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBK19793.2 - 0.11 11.8 0.1 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSP70 PF00012.15 CBK19794.2 - 3.4e-75 253.1 0.0 4.1e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK19794.2 - 1.4e-16 60.0 0.1 6e-15 54.6 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 CBK19794.2 - 2e-06 26.8 0.1 0.0021 16.9 0.0 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.3 CBK19794.2 - 0.0028 16.6 0.0 0.11 11.3 0.0 2.1 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.1 CBK19794.2 - 0.0087 15.8 0.4 35 4.2 0.0 3.9 4 0 0 4 4 4 0 Cell division protein FtsA Actin PF00022.14 CBK19794.2 - 0.12 10.7 0.0 0.82 8.0 0.0 1.9 1 1 0 1 1 1 0 Actin 14-3-3 PF00244.15 CBK19795.2 - 5.8e-88 293.9 5.1 6.4e-88 293.8 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein RGS PF00615.14 CBK19795.2 - 0.054 13.6 0.2 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Regulator of G protein signaling domain DUF2096 PF09869.4 CBK19795.2 - 0.065 13.1 1.5 0.1 12.4 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Helicase_C_2 PF13307.1 CBK19796.2 - 8.2e-52 175.5 0.2 5.3e-51 172.8 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBK19796.2 - 3.5e-43 147.0 0.2 2.6e-42 144.1 0.1 2.1 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 CBK19796.2 - 0.0039 17.0 0.1 2.8 7.7 0.1 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK19796.2 - 0.027 13.9 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK19796.2 - 0.051 13.7 0.2 17 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBK19796.2 - 0.17 11.1 0.2 8.7 5.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-C2H2 PF00096.21 CBK19797.2 - 4.3e-27 92.7 67.8 9.7e-06 25.6 1.3 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK19797.2 - 4.5e-25 86.1 59.4 8.3e-05 22.6 1.8 8.3 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK19797.2 - 4.3e-19 67.7 68.6 1.6e-05 24.9 1.1 9.5 9 1 0 9 9 9 5 Zinc-finger double domain PyrI_C PF02748.10 CBK19797.2 - 1.8e-05 24.0 20.3 0.1 12.0 0.2 4.2 3 1 0 4 4 4 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 CBK19797.2 - 0.0053 16.9 0.2 0.0053 16.9 0.1 9.2 9 2 0 9 9 9 3 C2H2-type zinc-finger domain Ogr_Delta PF04606.7 CBK19797.2 - 0.024 14.2 23.1 0.15 11.7 0.8 4.5 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 CBK19797.2 - 0.033 14.0 0.7 0.033 14.0 0.5 6.5 7 0 0 7 7 7 0 C2H2-type zinc finger zf-FCS PF06467.9 CBK19797.2 - 0.041 13.5 25.2 0.94 9.1 0.4 4.9 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 CBK19797.2 - 0.074 13.2 52.2 0.12 12.5 1.7 8.1 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBK19797.2 - 0.084 13.0 48.5 0.39 10.8 0.8 6.5 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding DUF2946 PF11162.3 CBK19797.2 - 0.11 12.6 1.3 3.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) YyzF PF14116.1 CBK19797.2 - 0.47 10.4 8.4 20 5.2 0.2 3.7 3 0 0 3 3 3 0 YyzF-like protein SIR2 PF02146.12 CBK19798.2 - 2.9e-32 111.8 0.0 3.1e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_2 PF13240.1 CBK19798.2 - 0.00034 19.9 1.3 0.19 11.2 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 CBK19798.2 - 0.0026 17.5 1.2 0.0048 16.6 0.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.1 CBK19798.2 - 0.0069 16.0 2.1 0.16 11.6 0.2 2.3 2 0 0 2 2 2 1 Nudix N-terminal zf-ribbon_3 PF13248.1 CBK19798.2 - 0.016 14.4 5.3 0.052 12.7 3.7 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 CBK19798.2 - 0.026 14.0 0.2 0.026 14.0 0.1 2.2 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ATPase-cat_bd PF12156.3 CBK19798.2 - 0.076 13.5 1.3 0.14 12.7 0.9 1.4 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Cys_rich_CPXG PF14255.1 CBK19798.2 - 0.12 12.2 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG zf-RING_3 PF14369.1 CBK19798.2 - 0.22 11.5 5.0 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 zinc-finger Zn-ribbon_8 PF09723.5 CBK19798.2 - 0.78 9.7 5.2 4 7.4 3.6 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.2 CBK19798.2 - 2.5 8.1 6.0 16 5.6 0.3 2.3 1 1 1 2 2 2 0 zinc-finger binding domain of transposase IS66 HemS PF05171.7 CBK19799.2 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain He_PIG PF05345.7 CBK19801.2 - 4e-10 39.5 25.3 2.6e-06 27.3 1.3 4.9 4 1 1 5 5 5 3 Putative Ig domain Shisa PF13908.1 CBK19801.2 - 0.00029 21.0 3.5 0.00065 19.9 2.4 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Tme5_EGF_like PF09064.5 CBK19801.2 - 0.0039 16.7 1.4 2.8 7.6 0.1 3.4 3 0 0 3 3 3 2 Thrombomodulin like fifth domain, EGF-like Neurensin PF14927.1 CBK19801.2 - 0.022 14.1 0.5 0.039 13.3 0.3 1.4 1 0 0 1 1 1 0 Neurensin HRM PF02793.17 CBK19801.2 - 0.028 14.4 6.7 6.3 6.8 0.1 4.2 4 0 0 4 4 4 0 Hormone receptor domain PIRT PF15099.1 CBK19801.2 - 0.039 13.1 0.8 0.11 11.7 0.6 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family hEGF PF12661.2 CBK19801.2 - 0.12 12.5 1.3 22 5.4 0.1 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF DUF4245 PF14030.1 CBK19801.2 - 0.18 11.5 3.8 0.4 10.3 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF3040 PF11239.3 CBK19801.2 - 0.21 11.6 2.7 0.45 10.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FAP PF07174.6 CBK19801.2 - 1.4 8.1 36.4 2.6 7.2 25.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Bromodomain PF00439.20 CBK19803.2 - 6e-08 32.5 0.1 2e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 Bromodomain DUF4055 PF13264.1 CBK19803.2 - 0.075 13.1 1.2 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Mnd1 PF03962.10 CBK19803.2 - 0.078 12.6 2.9 0.13 11.9 2.0 1.5 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 CBK19803.2 - 0.12 12.3 5.6 0.095 12.7 1.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CBK19803.2 - 0.45 10.0 3.6 12 5.4 2.5 2.2 1 1 0 1 1 1 0 IncA protein DUF3835 PF12927.2 CBK19803.2 - 3.1 8.8 7.1 4.3 8.3 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) SPT16 PF08644.6 CBK19804.2 - 1.5e-38 132.0 0.4 1.5e-38 132.0 0.3 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 CBK19804.2 - 2.6e-23 82.7 0.0 4.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CBK19804.2 - 5e-21 74.5 1.2 2.7e-20 72.1 0.1 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Fer2_4 PF13510.1 CBK19804.2 - 0.046 13.5 0.1 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Prefoldin_2 PF01920.15 CBK19805.2 - 2.8e-14 52.7 9.7 3.2e-14 52.5 6.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Myosin_tail_1 PF01576.14 CBK19805.2 - 0.00038 18.3 3.5 0.00038 18.3 2.4 1.9 2 0 0 2 2 2 1 Myosin tail Acyl-ACP_TE PF01643.12 CBK19805.2 - 0.01 14.8 0.5 0.015 14.2 0.2 1.3 1 1 0 1 1 1 0 Acyl-ACP thioesterase Prefoldin PF02996.12 CBK19805.2 - 0.012 15.2 10.8 0.047 13.3 2.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit AAA_13 PF13166.1 CBK19805.2 - 0.013 14.0 5.8 0.016 13.7 4.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 CBK19805.2 - 0.02 14.1 2.2 0.44 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.1 CBK19805.2 - 0.024 13.6 0.3 0.028 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lipoprotein_20 PF13942.1 CBK19805.2 - 0.031 13.8 1.3 0.031 13.8 0.9 1.9 2 0 0 2 2 2 0 YfhG lipoprotein Syntaxin-6_N PF09177.6 CBK19805.2 - 0.031 14.6 3.7 2.9 8.3 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RhoGEF PF00621.15 CBK19805.2 - 0.037 13.9 2.5 0.054 13.3 1.7 1.3 1 0 0 1 1 1 0 RhoGEF domain DASH_Dad3 PF08656.5 CBK19805.2 - 0.053 13.2 0.8 0.053 13.2 0.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DegS PF05384.6 CBK19805.2 - 0.054 12.6 5.9 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 Sensor protein DegS MIF4G_like_2 PF09090.6 CBK19805.2 - 0.081 12.1 3.0 0.1 11.8 2.1 1.1 1 0 0 1 1 1 0 MIF4G like HA2 PF04408.18 CBK19805.2 - 0.13 12.2 0.4 0.27 11.2 0.1 1.6 1 1 1 2 2 2 0 Helicase associated domain (HA2) Folliculin PF11704.3 CBK19805.2 - 0.13 11.8 4.7 1.2 8.7 0.2 2.0 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Fib_alpha PF08702.5 CBK19805.2 - 0.19 11.8 2.8 1.7 8.7 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.1 CBK19805.2 - 0.44 10.3 4.2 2.2 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Sas10_Utp3 PF04000.10 CBK19805.2 - 0.45 10.7 5.2 6.2 7.0 0.5 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DNA_topoisoIV PF00521.15 CBK19805.2 - 0.52 9.0 3.8 0.66 8.7 2.6 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF342 PF03961.8 CBK19805.2 - 0.58 8.5 11.8 4.1 5.7 8.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Med22 PF06179.7 CBK19805.2 - 0.65 10.0 8.9 4.1 7.4 0.6 2.1 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Phage_GPO PF05929.6 CBK19805.2 - 0.7 9.0 8.0 3.5 6.7 0.1 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3671 PF12420.3 CBK19805.2 - 1 9.3 4.2 1.8 8.5 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function COG2 PF06148.6 CBK19805.2 - 1.4 8.8 8.6 38 4.1 5.7 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 CBK19805.2 - 1.5 9.1 12.1 1.8e+02 2.5 8.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Tho2 PF11262.3 CBK19805.2 - 1.8 7.5 7.7 2.7 6.9 5.4 1.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.9 CBK19805.2 - 2.3 8.1 10.8 7.3 6.4 7.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NYD-SP28 PF14772.1 CBK19805.2 - 2.3 8.3 11.5 3.2 7.9 2.9 2.1 2 0 0 2 2 2 0 Sperm tail Nup54 PF13874.1 CBK19805.2 - 3.6 7.2 7.3 31 4.1 5.1 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 CDC37_N PF03234.9 CBK19805.2 - 3.9 7.7 12.0 10 6.3 8.3 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Seryl_tRNA_N PF02403.17 CBK19805.2 - 4 7.4 12.6 3.6 7.6 0.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 CBK19805.2 - 4.7 6.9 13.8 1.2 8.9 2.9 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CBK19805.2 - 5.5 6.5 12.8 3.3 7.2 3.1 2.1 1 1 1 2 2 2 0 IncA protein IFT20 PF14931.1 CBK19805.2 - 5.8 6.8 11.1 9.7 6.1 4.2 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 PCRF PF03462.13 CBK19805.2 - 6.1 6.5 8.4 11 5.6 1.6 2.2 2 0 0 2 2 2 0 PCRF domain Med21 PF11221.3 CBK19805.2 - 6.4 6.7 9.0 0.91 9.4 2.1 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Ax_dynein_light PF10211.4 CBK19805.2 - 7.5 6.3 10.5 11 5.7 0.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain CCDC-167 PF15188.1 CBK19805.2 - 8.2 6.4 10.9 28 4.7 4.2 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mannosyl_trans PF05007.8 CBK19807.2 - 9.3e-53 179.5 30.4 9.3e-53 179.5 21.1 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 CBK19807.2 - 1.8e-10 40.7 2.9 1.8e-10 40.7 2.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 CBK19807.2 - 3.4e-07 29.4 38.6 6.2e-07 28.6 26.7 1.4 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Adap_comp_sub PF00928.16 CBK19808.2 - 1.3e-25 89.9 0.0 2.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK19808.2 - 0.00015 21.4 0.4 0.00026 20.7 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2076 PF09849.4 CBK19808.2 - 0.033 14.2 5.4 0.051 13.6 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L34e PF01199.13 CBK19809.2 - 6.9e-26 90.3 7.0 6.9e-26 90.3 4.9 2.8 2 1 0 2 2 2 1 Ribosomal protein L34e FYVE PF01363.16 CBK19809.2 - 0.00019 21.2 4.4 0.00032 20.5 3.1 1.5 1 1 0 1 1 1 1 FYVE zinc finger NAD_kinase PF01513.16 CBK19810.2 - 6.9e-53 179.2 0.0 1.2e-52 178.4 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Radical_SAM PF04055.16 CBK19812.2 - 3.2e-23 82.6 0.0 6.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 CBK19812.2 - 0.0044 17.1 0.2 0.0044 17.1 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain PolC_DP2 PF03833.8 CBK19812.2 - 0.34 8.5 0.9 0.46 8.0 0.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PTPA PF03095.10 CBK19813.2 - 6.3e-90 301.3 0.0 7.6e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_20 PF00728.17 CBK19814.2 - 0.039 13.1 0.2 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain FANCI_HD2 PF14680.1 CBK19814.2 - 0.074 12.1 0.6 0.086 11.9 0.4 1.3 1 1 0 1 1 1 0 FANCI helical domain 2 Caudo_TAP PF02413.12 CBK19814.2 - 0.51 10.5 3.6 0.73 10.0 2.5 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Proteasome PF00227.21 CBK19815.2 - 1.2e-40 138.8 0.0 1.3e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CS PF04969.11 CBK19816.2 - 6.9e-13 48.9 0.7 1.1e-12 48.2 0.5 1.3 1 0 0 1 1 1 1 CS domain Apyrase PF06079.6 CBK19816.2 - 0.005 16.0 0.3 0.0066 15.6 0.2 1.2 1 0 0 1 1 1 1 Apyrase TetR_C_8 PF14278.1 CBK19816.2 - 0.062 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region SPRY PF00622.23 CBK19816.2 - 0.095 12.7 0.2 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 SPRY domain Mt_ATP-synt_D PF05873.7 CBK19816.2 - 0.17 11.5 1.5 1.2 8.7 0.4 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TAP42 PF04177.7 CBK19817.2 - 1.3e-24 86.7 13.3 1.5e-24 86.6 9.2 1.0 1 0 0 1 1 1 1 TAP42-like family SART-1 PF03343.8 CBK19817.2 - 0.0094 14.3 5.8 0.0095 14.3 4.0 1.0 1 0 0 1 1 1 1 SART-1 family DUF572 PF04502.8 CBK19817.2 - 7 5.7 14.1 15 4.7 9.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.14 CBK19818.2 - 4.3e-24 84.7 15.4 5e-24 84.5 10.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF867 PF05908.6 CBK19818.2 - 0.063 12.3 0.1 0.085 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Sigma70_ner PF04546.8 CBK19818.2 - 1.8 8.1 7.6 2.3 7.7 5.2 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 CBK19818.2 - 7.7 5.5 7.8 7.7 5.5 5.0 1.2 1 1 0 1 1 1 0 Myc amino-terminal region FAINT PF04385.10 CBK19819.2 - 0.0041 16.9 1.6 0.0044 16.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Scytalone_dh PF02982.9 CBK19819.2 - 0.1 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Scytalone dehydratase Bombinin PF05298.6 CBK19820.2 - 0.00055 19.4 0.2 0.001 18.5 0.0 1.5 1 1 0 1 1 1 1 Bombinin IFT43 PF15305.1 CBK19820.2 - 0.0019 18.2 0.5 0.0022 18.0 0.4 1.1 1 0 0 1 1 1 1 Intraflagellar transport protein 43 DUF1053 PF06327.9 CBK19820.2 - 0.047 14.0 1.1 0.06 13.6 0.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) MPP6 PF10175.4 CBK19820.2 - 0.37 11.1 3.0 0.27 11.6 0.3 1.9 1 1 0 2 2 2 0 M-phase phosphoprotein 6 Methyltransf_8 PF05148.10 CBK19822.2 - 3.3e-63 213.2 0.1 4.8e-63 212.7 0.1 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CBK19822.2 - 5.2e-05 23.6 0.0 0.00018 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK19822.2 - 0.00081 18.8 0.0 0.15 11.3 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain DUF2325 PF10087.4 CBK19822.2 - 0.079 12.8 0.2 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Ribosomal_L5_C PF00673.16 CBK19823.2 - 2.8e-22 78.2 0.0 4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBK19823.2 - 2.7e-18 65.4 0.6 1.4e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Dyp_perox PF04261.7 CBK19824.2 - 5.4e-66 222.4 0.0 5.9e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family GTP_EFTU PF00009.22 CBK19825.2 - 3.1e-32 111.5 0.0 1.5e-31 109.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBK19825.2 - 5.5e-18 64.8 0.0 1.7e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CBK19825.2 - 7.1e-13 48.4 7.7 2.3e-10 40.4 0.1 4.2 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK19825.2 - 1.2e-07 31.6 0.0 5.7e-07 29.5 0.0 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBK19825.2 - 1.7e-06 27.5 0.9 0.0091 15.6 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 CBK19825.2 - 4.5e-05 23.1 0.0 0.00013 21.5 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 CBK19825.2 - 5e-05 23.7 0.0 0.00024 21.5 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CBK19825.2 - 0.00057 20.0 1.2 0.002 18.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CBK19825.2 - 0.00061 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Trypan_PARP PF05887.6 CBK19825.2 - 0.00073 19.3 38.9 0.00073 19.3 27.0 4.5 3 1 1 4 4 3 1 Procyclic acidic repetitive protein (PARP) Ras PF00071.17 CBK19825.2 - 0.0024 17.2 0.0 0.013 14.9 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 CBK19825.2 - 0.12 12.3 0.0 0.12 12.3 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain Fer2_3 PF13085.1 CBK19826.2 - 7.4e-33 112.6 0.1 1.3e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK19826.2 - 1.1e-09 38.5 6.9 1.1e-09 38.5 4.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK19826.2 - 1.4e-09 37.8 4.9 1.4e-09 37.8 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK19826.2 - 5.3e-06 26.7 3.2 5.3e-06 26.7 2.2 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CBK19826.2 - 0.00011 21.9 0.4 0.00011 21.9 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CBK19826.2 - 0.00018 21.7 8.4 0.063 13.5 0.8 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK19826.2 - 0.00023 20.8 3.5 0.00023 20.8 2.4 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK19826.2 - 0.0021 18.3 5.1 0.0021 18.3 3.6 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBK19826.2 - 3.3 8.3 8.3 2.4 8.7 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 CBK19826.2 - 5.7 7.0 19.5 1.4 9.0 2.8 4.1 4 0 0 4 4 4 0 4Fe-4S binding domain Got1 PF04178.7 CBK19827.2 - 0.00023 21.2 12.9 0.00031 20.8 8.7 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family B12D PF06522.6 CBK19827.2 - 0.37 10.5 0.1 0.37 10.5 0.1 2.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit TRAP_alpha PF03896.11 CBK19829.2 - 4.1e-09 35.8 3.3 4.9e-09 35.5 2.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ribosomal_S5 PF00333.15 CBK19830.2 - 4.6e-26 90.3 2.2 4.6e-26 90.3 1.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBK19830.2 - 3.5e-24 83.8 0.0 5.9e-24 83.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain dCMP_cyt_deam_1 PF00383.17 CBK19831.2 - 4.4e-18 64.8 0.1 6e-16 57.9 0.1 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CBK19831.2 - 3e-06 27.1 0.5 0.00013 21.8 0.3 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 CBK19831.2 - 0.016 14.8 0.1 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 APOBEC-like N-terminal domain Dus PF01207.12 CBK19832.2 - 8.9e-48 162.6 0.0 1.1e-29 103.2 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) GOLD_2 PF13897.1 CBK19833.2 - 0.00065 19.9 1.7 0.002 18.3 0.0 2.1 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.19 CBK19833.2 - 0.0061 16.3 7.5 0.028 14.1 5.3 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4349 PF14257.1 CBK19833.2 - 0.024 13.8 5.8 0.033 13.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AAA_23 PF13476.1 CBK19833.2 - 0.031 14.6 5.5 0.035 14.4 3.8 1.1 1 0 0 1 1 1 0 AAA domain Psu PF07455.6 CBK19833.2 - 0.074 12.5 3.1 0.073 12.5 1.6 1.3 1 1 0 1 1 1 0 Phage polarity suppression protein (Psu) Atg14 PF10186.4 CBK19833.2 - 0.18 10.7 9.1 0.23 10.3 6.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 CBK19833.2 - 0.28 10.2 8.3 0.36 9.8 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4201 PF13870.1 CBK19833.2 - 0.31 10.4 17.8 0.19 11.1 10.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2051 PF09738.4 CBK19833.2 - 0.33 10.1 10.9 0.12 11.5 5.5 1.7 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) APG6 PF04111.7 CBK19833.2 - 2.9 6.8 11.6 3.7 6.4 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 CBK19833.2 - 4 7.2 13.4 1.4 8.7 2.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mgr1 PF08602.5 CBK19833.2 - 5.6 5.8 6.5 7.1 5.5 4.5 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Bap31 PF05529.7 CBK19833.2 - 6.7 6.1 13.7 15 5.0 9.5 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 CBK19833.2 - 7.5 7.0 10.0 3.4 8.1 0.5 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Aminotran_1_2 PF00155.16 CBK19835.2 - 1.1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK19835.2 - 0.0025 17.0 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Helicase_IV_N PF12462.3 CBK19836.2 - 0.0057 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal PTPA PF03095.10 CBK19836.2 - 0.11 11.6 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein TPR_11 PF13414.1 CBK19837.2 - 1.5e-24 85.4 8.3 1.5e-17 63.0 1.1 3.9 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 CBK19837.2 - 4.4e-14 51.3 12.4 5e-05 22.7 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK19837.2 - 1.7e-13 49.3 12.5 0.00095 18.9 0.1 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBK19837.2 - 2.8e-09 37.3 1.0 0.0058 17.2 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK19837.2 - 4.4e-09 36.1 5.3 8.9e-05 22.3 1.0 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CBK19837.2 - 5.3e-07 29.6 6.0 0.0039 17.2 2.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBK19837.2 - 5.9e-07 28.8 12.7 0.027 14.2 0.5 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK19837.2 - 1.2e-06 28.3 0.5 0.056 13.3 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBK19837.2 - 3.6e-06 26.3 0.4 0.18 11.6 0.0 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK19837.2 - 5.6e-06 26.5 0.5 0.58 10.9 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBK19837.2 - 0.00065 19.5 0.0 4.2 7.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 CBK19837.2 - 0.09 12.6 0.2 0.09 12.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBK19837.2 - 0.13 12.5 7.1 9.3 6.6 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ComJ PF11033.3 CBK19837.2 - 0.15 11.6 0.3 0.42 10.2 0.0 1.9 2 1 0 2 2 2 0 Competence protein J (ComJ) Clathrin PF00637.15 CBK19837.2 - 0.21 11.1 3.4 2.5 7.6 0.0 3.5 4 1 1 5 5 5 0 Region in Clathrin and VPS TPR_17 PF13431.1 CBK19837.2 - 0.26 11.5 2.7 16 6.0 0.0 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK19837.2 - 0.54 10.8 9.0 30 5.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 CBK19839.2 - 1.2e-32 113.1 0.2 1.4e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBK19839.2 - 2.7e-16 60.0 0.0 3.3e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBK19839.2 - 4.9e-16 58.9 0.2 6.7e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBK19839.2 - 0.00043 19.7 0.3 0.0013 18.2 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 CBK19839.2 - 0.0014 18.4 0.3 0.0014 18.4 0.2 2.0 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBK19839.2 - 0.002 17.2 0.3 0.0044 16.0 0.2 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 CBK19839.2 - 0.005 15.7 0.1 0.0078 15.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CBK19839.2 - 0.0093 15.9 0.1 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Ubie_methyltran PF01209.13 CBK19839.2 - 0.0093 15.1 0.2 0.02 13.9 0.1 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.13 CBK19839.2 - 0.05 13.2 0.2 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S6e PF01092.14 CBK19840.2 - 9.8e-59 196.5 0.3 1.7e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Nicastrin PF05450.10 CBK19841.2 - 4.3e-11 42.5 0.0 8.7e-10 38.2 0.0 2.2 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 CBK19841.2 - 0.00017 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Not3 PF04065.10 CBK19842.2 - 3.1e-18 65.9 4.9 4.7e-18 65.3 3.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CBK19842.2 - 2.6e-10 40.3 0.7 6.9e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family PFEMP PF03011.10 CBK19842.2 - 0.11 12.8 1.0 0.2 12.0 0.7 1.4 1 0 0 1 1 1 0 PFEMP DBL domain Atg14 PF10186.4 CBK19842.2 - 0.24 10.3 5.4 0.34 9.8 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EMP70 PF02990.11 CBK19843.2 - 7.8e-134 446.9 17.9 9.9e-134 446.6 12.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3373 PF11853.3 CBK19844.2 - 0.0067 15.0 3.5 0.0079 14.7 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) Atg14 PF10186.4 CBK19844.2 - 0.053 12.4 2.1 0.05 12.5 1.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 CBK19844.2 - 0.07 12.4 1.2 0.084 12.2 0.8 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GrpE PF01025.14 CBK19844.2 - 0.07 12.6 3.1 0.069 12.6 2.2 1.1 1 0 0 1 1 1 0 GrpE Lge1 PF11488.3 CBK19844.2 - 0.095 12.9 2.4 0.11 12.7 1.7 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 FlxA PF14282.1 CBK19844.2 - 0.18 11.7 3.1 0.2 11.6 2.1 1.2 1 0 0 1 1 1 0 FlxA-like protein bZIP_1 PF00170.16 CBK19844.2 - 0.22 11.4 3.6 0.26 11.2 2.5 1.1 1 0 0 1 1 1 0 bZIP transcription factor DUF641 PF04859.7 CBK19844.2 - 0.32 10.7 3.8 0.33 10.7 2.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 CBK19844.2 - 0.44 10.3 6.9 0.51 10.1 4.8 1.1 1 0 0 1 1 1 0 Prefoldin subunit ATP-synt_E PF05680.7 CBK19844.2 - 0.48 10.3 3.9 0.51 10.3 2.7 1.1 1 0 0 1 1 1 0 ATP synthase E chain Spc24 PF08286.6 CBK19844.2 - 0.66 9.6 4.3 0.79 9.4 3.0 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Vfa1 PF08432.5 CBK19844.2 - 1.5 8.8 6.0 1.4 8.8 4.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.4 CBK19844.2 - 6.8 4.8 7.0 6.5 4.9 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein BPL_N PF09825.4 CBK19846.2 - 3.3e-50 170.9 0.1 3.8e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.9 CBK19846.2 - 0.00066 19.2 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF869 PF05911.6 CBK19847.2 - 0.0011 17.3 33.8 0.0011 17.3 23.4 2.0 2 0 0 2 2 2 1 Plant protein of unknown function (DUF869) GAS PF13851.1 CBK19847.2 - 2.3 7.3 64.7 0.37 9.9 12.2 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 CBK19847.2 - 3.7 6.1 60.2 0.17 10.5 19.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Mnd1 PF03962.10 CBK19847.2 - 8 6.0 58.3 0.27 10.8 5.1 4.1 1 1 3 4 4 4 0 Mnd1 family PDDEXK_1 PF12705.2 CBK19848.2 - 1.7e-07 30.8 0.1 3.8e-06 26.4 0.1 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily CitMHS PF03600.11 CBK19849.2 - 2.1e-54 184.4 45.2 7.7e-54 182.5 20.2 2.3 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.10 CBK19849.2 - 6.8e-19 68.1 33.3 1e-18 67.5 23.1 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein Na_sulph_symp PF00939.14 CBK19849.2 - 1.2e-12 47.4 42.2 1.2e-08 34.2 11.6 3.2 2 1 1 3 3 3 2 Sodium:sulfate symporter transmembrane region DUF3989 PF13150.1 CBK19850.2 - 0.13 11.7 0.4 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Mur_ligase_M PF08245.7 CBK19851.2 - 1.1e-11 45.1 0.1 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain NTPase_1 PF03266.10 CBK19851.2 - 0.088 12.5 0.2 0.17 11.6 0.1 1.5 2 0 0 2 2 2 0 NTPase zf-RING_2 PF13639.1 CBK19852.2 - 3.3e-08 33.2 1.5 5.5e-08 32.5 1.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBK19852.2 - 5.4e-07 29.2 1.8 9.4e-07 28.4 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBK19852.2 - 2.1e-05 24.0 0.7 3.6e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK19852.2 - 0.00014 21.8 1.6 0.00025 20.9 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK19852.2 - 0.00052 19.6 1.1 0.00097 18.7 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBK19852.2 - 0.00078 19.4 0.6 0.002 18.2 0.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger Prok-RING_1 PF14446.1 CBK19852.2 - 0.0018 17.9 1.8 0.0038 16.9 0.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 CBK19852.2 - 0.035 13.9 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CBK19852.2 - 0.041 13.5 1.1 0.088 12.5 0.7 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 CBK19852.2 - 0.15 11.7 1.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Microtub_bind PF13931.1 CBK19852.2 - 0.23 11.6 3.4 0.4 10.8 2.3 1.4 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding zf-C3HC4_4 PF15227.1 CBK19852.2 - 0.77 9.6 2.8 1.8 8.4 2.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CDC45 PF02724.9 CBK19852.2 - 3.2 5.6 7.2 4.5 5.1 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0113 PF03657.8 CBK19853.2 - 1.6e-13 50.6 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 CBK19853.2 - 0.0024 17.9 0.0 0.042 13.9 0.0 2.2 1 1 1 2 2 2 1 pre-rRNA processing and ribosome biogenesis PP1 PF07430.6 CBK19853.2 - 0.035 13.6 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 PUA PF01472.15 CBK19853.2 - 0.055 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain SNase PF00565.12 CBK19854.2 - 0.0003 21.0 0.0 0.00037 20.7 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TUDOR PF00567.19 CBK19854.2 - 0.058 13.2 0.0 0.43 10.4 0.0 2.2 3 0 0 3 3 3 0 Tudor domain Ras PF00071.17 CBK19855.2 - 1.3e-52 177.5 0.0 1.5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK19855.2 - 7e-15 55.5 0.0 1.4e-14 54.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK19855.2 - 2.9e-13 49.4 0.0 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK19855.2 - 8.9e-07 28.2 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBK19855.2 - 3.5e-06 26.5 0.0 2.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK19855.2 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBK19855.2 - 0.046 13.1 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBK19855.2 - 0.068 12.6 0.1 0.19 11.2 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 CBK19856.2 - 3e-31 108.1 0.0 6.1e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK19856.2 - 4.3e-23 80.9 0.0 1.4e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ELMO_CED12 PF04727.8 CBK19857.2 - 3.5e-32 111.2 0.2 8.6e-32 110.0 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family Glyco_transf_20 PF00982.16 CBK19858.2 - 2e-79 267.3 0.0 2.5e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CBK19858.2 - 1.9e-48 164.4 0.1 4.7e-48 163.1 0.0 1.7 1 1 0 1 1 1 1 Trehalose-phosphatase DUF4123 PF13503.1 CBK19858.2 - 0.018 14.9 0.1 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) ApbE PF02424.10 CBK19858.2 - 0.044 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 ApbE family Hydrolase_3 PF08282.7 CBK19858.2 - 0.089 12.3 0.0 2.6 7.5 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Coatomer_WDAD PF04053.9 CBK19859.2 - 6.8e-112 374.4 0.1 4e-110 368.6 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 CBK19859.2 - 6e-52 171.7 11.2 2.7e-11 42.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_12 PF13424.1 CBK19859.2 - 5.9e-05 22.9 0.0 0.0005 19.9 0.0 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat Nup160 PF11715.3 CBK19859.2 - 0.0028 15.8 2.1 0.13 10.3 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 TPR_19 PF14559.1 CBK19859.2 - 0.072 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Acyltransferase PF01553.16 CBK19860.2 - 8.4e-08 31.7 0.0 9.2e-07 28.3 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase SURF2 PF05477.6 CBK19860.2 - 0.077 12.1 10.3 0.15 11.1 7.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.7 CBK19860.2 - 1.4 8.1 8.7 2 7.6 6.0 1.1 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 CBK19860.2 - 2.7 8.0 14.5 5.1 7.1 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 CBK19860.2 - 3.7 5.9 13.9 5.5 5.3 9.7 1.1 1 0 0 1 1 1 0 Daxx Family Lin-8 PF03353.10 CBK19860.2 - 4.6 6.4 10.4 7.7 5.7 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MDFI PF15316.1 CBK19860.2 - 5.3 6.9 4.8 9.9 6.1 3.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Nop14 PF04147.7 CBK19860.2 - 5.7 4.7 15.6 8.7 4.1 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBK19860.2 - 6.3 4.7 6.5 9.7 4.0 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CBK19860.2 - 8.4 5.4 9.2 10 5.1 5.3 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DnaJ PF00226.26 CBK19861.2 - 3.1e-09 36.4 0.2 6.6e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Iron_traffic PF04362.9 CBK19861.2 - 0.14 11.6 1.4 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking DUF4207 PF13904.1 CBK19861.2 - 0.17 11.2 7.6 0.23 10.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PC4 PF02229.11 CBK19862.2 - 1.8e-17 62.2 0.0 2.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Ribosomal_L34e PF01199.13 CBK19863.2 - 6.9e-26 90.3 7.0 6.9e-26 90.3 4.9 2.8 2 1 0 2 2 2 1 Ribosomal protein L34e FYVE PF01363.16 CBK19863.2 - 0.00019 21.2 4.4 0.00032 20.5 3.1 1.5 1 1 0 1 1 1 1 FYVE zinc finger Clat_adaptor_s PF01217.15 CBK19864.2 - 0.00017 21.3 0.4 0.00027 20.6 0.3 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CBK19864.2 - 0.035 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Adaptor complexes medium subunit family DUF2076 PF09849.4 CBK19864.2 - 8.7 6.3 12.4 0.071 13.1 2.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2228 PF10228.4 CBK19866.2 - 0.00046 19.8 0.3 0.00046 19.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF1825 PF08855.5 CBK19866.2 - 0.00074 19.4 1.2 0.0012 18.8 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) Apolipoprotein PF01442.13 CBK19866.2 - 0.0018 17.8 0.7 0.0023 17.4 0.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phage_Mu_Gam PF07352.7 CBK19866.2 - 0.0019 17.7 2.2 0.0026 17.2 1.5 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein ISG65-75 PF11727.3 CBK19866.2 - 0.0028 16.7 1.1 0.0033 16.5 0.7 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Cnl2_NKP2 PF09447.5 CBK19866.2 - 0.017 14.7 0.6 0.017 14.7 0.4 1.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein THOC7 PF05615.8 CBK19866.2 - 0.018 15.3 4.1 0.03 14.5 2.8 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Effector_1 PF04518.7 CBK19866.2 - 0.023 13.6 1.0 0.025 13.5 0.7 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF2215 PF10225.4 CBK19866.2 - 0.038 13.4 0.3 0.044 13.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Phasin PF05597.6 CBK19866.2 - 0.053 13.2 2.6 0.11 12.2 1.8 1.5 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Gln-synt_N PF03951.14 CBK19866.2 - 0.091 12.3 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain IncA PF04156.9 CBK19866.2 - 0.091 12.3 1.8 0.12 12.0 1.2 1.2 1 0 0 1 1 1 0 IncA protein YlqD PF11068.3 CBK19866.2 - 0.097 12.7 5.0 0.13 12.2 3.5 1.2 1 0 0 1 1 1 0 YlqD protein DUF853 PF05872.7 CBK19866.2 - 0.15 10.3 0.3 0.17 10.1 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) V_ATPase_I PF01496.14 CBK19866.2 - 0.17 9.7 1.1 0.18 9.5 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.8 CBK19866.2 - 0.2 12.0 1.1 0.4 11.0 0.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 CBK19866.2 - 0.21 10.5 3.8 0.28 10.2 2.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.9 CBK19866.2 - 0.27 11.1 3.3 0.38 10.6 2.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PRKCSH-like PF12999.2 CBK19866.2 - 0.28 10.7 3.6 0.52 9.8 2.5 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Peptidase_C97 PF05903.9 CBK19868.2 - 7.7e-31 106.9 0.0 1.1e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4231 PF14015.1 CBK19868.2 - 7.3 6.6 7.3 13 5.8 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) TFIIS_C PF01096.13 CBK19869.2 - 2.2e-19 68.7 6.6 3.8e-19 68.0 4.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 CBK19869.2 - 1.7e-14 53.8 0.1 2.6e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Zn_Tnp_IS1595 PF12760.2 CBK19869.2 - 0.014 15.1 1.0 0.056 13.2 0.7 2.1 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 CBK19869.2 - 0.09 12.4 4.4 0.075 12.7 1.1 2.2 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 CBK19869.2 - 0.13 11.6 1.6 0.35 10.2 1.1 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain TPR_1 PF00515.23 CBK19869.2 - 0.27 10.9 1.4 0.56 9.9 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 CBK19870.2 - 6.8e-17 61.2 0.0 8.9e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBK19870.2 - 5.6e-08 32.8 0.0 8.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK19870.2 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CBK19870.2 - 1.4e-05 24.9 0.0 4.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBK19870.2 - 0.00087 19.4 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBK19870.2 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CBK19870.2 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SMC_N PF02463.14 CBK19871.2 - 9e-14 51.2 11.4 2.1e-07 30.3 8.3 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK19871.2 - 2.7e-13 49.9 0.2 1.6e-12 47.4 0.0 2.6 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK19871.2 - 0.00089 19.3 3.3 0.2 11.6 0.0 3.0 2 1 1 3 3 3 2 AAA domain tRNA-synt_2b PF00587.20 CBK19872.2 - 7.1e-34 116.8 0.0 3.5e-33 114.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK19872.2 - 1.4e-15 56.9 0.0 4.9e-15 55.2 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain DUF4063 PF13272.1 CBK19872.2 - 0.13 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) Abhydrolase_2 PF02230.11 CBK19873.2 - 3.5e-35 121.4 0.0 4.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CBK19873.2 - 1.2e-07 31.8 0.0 1.7e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBK19873.2 - 1.7e-07 31.1 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBK19873.2 - 1.5e-05 24.6 0.0 3.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 CBK19873.2 - 0.00021 20.8 0.0 0.00058 19.3 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF2974 PF11187.3 CBK19873.2 - 0.035 13.4 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.7 CBK19873.2 - 0.062 11.7 0.0 0.09 11.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 CBK19873.2 - 0.068 12.4 0.0 0.43 9.7 0.0 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase CDC50 PF03381.10 CBK19874.2 - 2.9e-65 220.2 0.0 6.4e-65 219.0 0.0 1.4 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family BAH PF01426.13 CBK19876.2 - 0.00051 19.7 0.0 0.00086 19.0 0.0 1.4 1 1 0 1 1 1 1 BAH domain Ribosomal_L22 PF00237.14 CBK19876.2 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e tRNA-synt_1c PF00749.16 CBK19877.2 - 5.6e-97 324.1 1.5 7.5e-97 323.7 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBK19877.2 - 1.6e-36 125.5 0.2 3.2e-36 124.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CBK19877.2 - 6.9e-06 26.4 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBK19877.2 - 0.00092 19.0 0.0 0.0031 17.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBK19877.2 - 0.0047 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 CBK19877.2 - 0.0074 15.4 0.1 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain hSac2 PF12456.3 CBK19878.2 - 0.0073 15.6 1.2 0.42 10.0 0.0 3.1 1 1 2 3 3 3 1 Inositol phosphatase LRR_8 PF13855.1 CBK19878.2 - 0.041 13.6 2.4 6.1 6.6 0.1 3.0 1 1 2 3 3 3 0 Leucine rich repeat Sec63 PF02889.11 CBK19879.2 - 3.3e-131 437.2 9.3 1.2e-81 274.4 0.6 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBK19879.2 - 3.7e-52 176.2 2.4 3.5e-25 88.4 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CBK19879.2 - 1.4e-17 64.1 0.1 6.6e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBK19879.2 - 3e-15 55.8 0.0 2.7e-06 27.1 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBK19879.2 - 5.2e-08 33.0 0.7 0.0055 16.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 CBK19879.2 - 0.00012 22.2 1.6 0.077 13.1 0.0 3.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBK19879.2 - 0.00081 19.0 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 CBK19879.2 - 0.0022 17.3 3.0 0.7 9.1 0.0 3.3 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 CBK19879.2 - 0.003 17.0 0.0 0.37 10.1 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 CBK19879.2 - 0.0083 15.0 0.0 0.36 9.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.11 CBK19879.2 - 0.0083 15.3 0.1 0.28 10.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 CBK19879.2 - 0.019 14.3 0.7 1 8.7 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein HhH-GPD PF00730.20 CBK19880.2 - 2.1e-20 73.0 0.0 4.1e-20 72.0 0.0 1.4 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBK19880.2 - 1.5e-08 33.8 0.9 2.4e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CBK19880.2 - 0.075 13.2 1.2 0.14 12.3 0.8 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III zf-4CXXC_R1 PF10497.4 CBK19881.2 - 0.068 13.3 15.5 0.12 12.4 10.8 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_3 PF13920.1 CBK19882.2 - 8.4e-05 22.1 13.8 0.00016 21.2 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK19882.2 - 0.00031 20.4 16.6 0.00062 19.4 11.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBK19882.2 - 0.00043 20.0 15.0 0.00043 20.0 10.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBK19882.2 - 0.0077 16.2 16.8 0.017 15.1 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK19882.2 - 0.29 10.8 15.5 0.72 9.5 10.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBK19882.2 - 0.57 9.7 10.8 3.4 7.2 3.6 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 CBK19882.2 - 4 7.2 12.3 11 5.8 8.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger CENP-F_leu_zip PF10473.4 CBK19883.2 - 0.0096 15.7 132.6 0.097 12.5 14.4 6.5 1 1 6 7 7 7 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 CBK19883.2 - 4.7 6.6 94.3 0.084 12.3 16.8 6.0 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) GAS PF13851.1 CBK19883.2 - 9.7 5.3 111.5 0.025 13.7 8.6 6.3 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 CBK19884.2 - 0.029 14.2 2.9 0.033 14.0 2.0 1.1 1 0 0 1 1 1 0 Tropomyosin like WD40_alt PF14077.1 CBK19884.2 - 0.12 12.0 0.1 0.38 10.4 0.1 1.9 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF3338 PF11819.3 CBK19884.2 - 0.14 11.6 0.7 0.24 10.8 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) Packaging_FI PF14000.1 CBK19884.2 - 0.88 9.7 7.4 0.37 10.9 0.4 2.0 1 1 1 2 2 2 0 DNA packaging protein FI Glyco_hydro_20 PF00728.17 CBK19885.2 - 9.1e-81 271.7 6.8 1.3e-80 271.2 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBK19885.2 - 4.1e-24 85.6 0.1 1.1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBK19885.2 - 1.5e-07 31.9 0.0 2.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.1 CBK19885.2 - 0.043 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 dUTPase PF00692.14 CBK19886.2 - 5.7e-36 122.8 0.0 1.2e-34 118.5 0.0 2.0 1 1 0 1 1 1 1 dUTPase tRNA-synt_1 PF00133.17 CBK19887.2 - 7.1e-219 727.7 0.0 9.3e-219 727.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBK19887.2 - 3.4e-24 85.3 0.0 7.1e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBK19887.2 - 7e-18 64.4 1.3 3.3e-06 26.0 0.1 3.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBK19887.2 - 9.8e-05 21.6 0.0 0.00078 18.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain MutS_V PF00488.16 CBK19888.2 - 3e-83 278.8 0.5 5.4e-83 277.9 0.3 1.5 1 0 0 1 1 1 1 MutS domain V S1-P1_nuclease PF02265.11 CBK19888.2 - 2.3e-37 128.9 0.0 3.7e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 S1/P1 Nuclease MutS_I PF01624.15 CBK19888.2 - 1.9e-29 102.0 0.0 1.7e-28 98.9 0.0 2.6 2 1 0 2 2 2 1 MutS domain I MutS_III PF05192.13 CBK19888.2 - 1.1e-27 97.1 1.4 3.6e-27 95.4 0.5 2.3 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CBK19888.2 - 2.7e-14 53.4 0.0 6.3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CBK19888.2 - 3.5e-09 36.7 0.0 1e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 CBK19888.2 - 0.0042 17.4 0.2 0.019 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBK19888.2 - 0.028 14.5 0.1 0.27 11.3 0.0 2.6 1 1 1 2 2 2 0 AAA domain zf-LITAF-like PF10601.4 CBK19889.2 - 3.8e-09 36.2 9.8 4.5e-05 23.2 1.8 2.3 1 1 1 2 2 2 2 LITAF-like zinc ribbon domain Folate_carrier PF01770.13 CBK19889.2 - 0.077 11.5 2.1 0.1 11.0 1.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier Zn_Tnp_IS1595 PF12760.2 CBK19889.2 - 0.17 11.7 1.5 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain 2TM PF13239.1 CBK19889.2 - 1.5 8.9 5.6 2.4 8.2 3.9 1.4 1 0 0 1 1 1 0 2TM domain YjgP_YjgQ PF03739.9 CBK19889.2 - 1.8 7.2 9.2 7.1 5.2 6.4 1.8 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4131 PF13567.1 CBK19889.2 - 7.3 5.9 9.0 10 5.4 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HRM PF02793.17 CBK19890.2 - 5e-09 36.0 3.7 4.2e-07 29.8 0.7 2.6 1 1 1 2 2 2 2 Hormone receptor domain RINGv PF12906.2 CBK19890.2 - 0.019 15.0 1.4 0.036 14.1 0.2 2.0 2 0 0 2 2 2 0 RING-variant domain Pacifastin_I PF05375.8 CBK19890.2 - 1.3 8.5 4.7 6.1 6.4 0.0 3.2 4 0 0 4 4 4 0 Pacifastin inhibitor (LCMII) UDPG_MGDP_dh_N PF03721.9 CBK19891.2 - 2.1e-50 170.6 0.0 5e-50 169.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 CBK19891.2 - 3.6e-25 87.9 0.0 7.1e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 CBK19891.2 - 9.1e-22 77.2 0.4 3.3e-21 75.4 0.3 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.10 CBK19891.2 - 2.9e-06 27.2 0.1 2e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CBK19891.2 - 8e-05 22.3 0.4 0.00088 18.9 0.0 2.6 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBK19891.2 - 0.0019 17.4 0.3 0.46 9.6 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 CBK19891.2 - 0.02 13.8 1.0 1.7 7.4 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 CBK19891.2 - 0.052 13.2 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 CBK19891.2 - 0.1 12.9 1.6 0.56 10.6 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CBK19891.2 - 0.11 12.5 3.1 4.9 7.1 0.0 3.4 4 0 0 4 4 4 0 TrkA-N domain UQ_con PF00179.21 CBK19892.2 - 4.6e-47 158.9 0.0 6.1e-47 158.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ArfGap PF01412.13 CBK19893.2 - 2.2e-36 124.1 0.2 8.4e-36 122.3 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF159 PF02586.9 CBK19893.2 - 0.004 16.7 2.6 0.009 15.5 1.8 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Ribosomal_L44 PF00935.14 CBK19894.2 - 2.1e-32 110.9 12.2 2.1e-32 110.9 8.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 CBK19894.2 - 0.03 14.5 4.0 0.03 14.5 2.8 2.8 2 1 0 2 2 2 0 Ribosomal protein L33 DUF1272 PF06906.6 CBK19894.2 - 0.21 11.4 3.5 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UBR PF02207.15 CBK19894.2 - 0.3 10.8 4.8 0.49 10.1 0.6 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) SNase PF00565.12 CBK19894.2 - 0.74 10.0 3.2 2.3 8.5 0.2 2.1 1 1 1 2 2 2 0 Staphylococcal nuclease homologue NOB1_Zn_bind PF08772.6 CBK19894.2 - 1.1 9.1 7.8 0.082 12.7 1.2 2.0 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.11 CBK19894.2 - 2.9 7.8 8.6 8.7 6.3 5.9 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-DNL PF05180.7 CBK19894.2 - 4.8 6.9 6.8 13 5.5 0.7 2.3 2 0 0 2 2 2 0 DNL zinc finger Melibiase PF02065.13 CBK19895.2 - 2.1e-12 46.4 2.3 3.2e-11 42.5 0.3 2.4 2 0 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 CBK19895.2 - 0.0019 17.3 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 LRR_8 PF13855.1 CBK19897.2 - 0.00019 21.0 9.1 0.07 12.8 0.1 4.4 3 2 1 4 4 4 3 Leucine rich repeat PLRV_ORF5 PF01690.12 CBK19897.2 - 0.0002 20.6 5.4 0.0003 20.0 3.8 1.1 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein hSac2 PF12456.3 CBK19897.2 - 0.0095 15.3 0.5 0.65 9.4 0.0 3.4 2 1 2 4 4 4 1 Inositol phosphatase LRR_4 PF12799.2 CBK19897.2 - 0.19 11.3 9.9 13 5.5 0.3 4.9 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) DNA_pol_B_2 PF03175.8 CBK19898.2 - 1.1e-07 30.9 7.9 0.00052 18.8 0.3 3.4 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral TPT PF03151.11 CBK19899.2 - 2.7e-15 56.3 35.5 7.5e-15 54.8 8.4 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CBK19899.2 - 2.5e-10 39.7 27.8 3.6e-10 39.2 19.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBK19899.2 - 2.2e-06 27.6 33.4 0.00019 21.4 7.7 2.8 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBK19899.2 - 1.4 9.1 28.9 0.033 14.3 5.0 3.1 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Sas10_Utp3 PF04000.10 CBK19900.2 - 7.4e-10 38.8 0.5 9.7e-10 38.5 0.4 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF806 PF05657.6 CBK19900.2 - 0.066 13.2 0.1 0.076 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF806) Methyltransf_1N PF02870.10 CBK19900.2 - 0.086 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DPRP PF04244.8 CBK19900.2 - 0.094 12.2 0.2 0.1 12.1 0.2 1.0 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein WES_acyltransf PF03007.11 CBK19901.2 - 6.8e-06 25.8 0.0 2e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Exo70 PF03081.10 CBK19902.2 - 9.2e-05 21.3 0.8 0.00011 21.1 0.5 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Beach PF02138.13 CBK19903.2 - 2e-80 270.0 0.2 3.7e-80 269.2 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CBK19903.2 - 6.7e-08 32.3 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH dUTPase PF00692.14 CBK19905.2 - 9.4e-37 125.3 0.0 2e-35 121.0 0.0 2.1 1 1 0 1 1 1 1 dUTPase Ribosomal_S25 PF03297.10 CBK19906.2 - 3.7e-26 91.2 1.5 8e-26 90.1 1.0 1.5 1 0 0 1 1 1 1 S25 ribosomal protein Baculo_gp64 PF03273.8 CBK19906.2 - 0.19 9.8 2.8 0.095 10.8 0.5 1.5 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family Adaptin_N PF01602.15 CBK19907.2 - 2.9e-88 296.4 11.8 3.5e-88 296.2 8.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CBK19907.2 - 4.8e-14 52.2 0.0 1.4e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CBK19907.2 - 1.4e-10 41.5 0.0 2.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Daxx PF03344.10 CBK19907.2 - 3.3e-05 22.6 24.9 5.3e-05 21.9 17.2 1.3 1 0 0 1 1 1 1 Daxx Family HEAT_2 PF13646.1 CBK19907.2 - 0.00018 21.7 0.0 0.0067 16.6 0.0 3.3 1 1 1 2 2 2 1 HEAT repeats Nop14 PF04147.7 CBK19907.2 - 0.0089 14.0 42.7 0.015 13.2 29.6 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 CBK19907.2 - 0.044 13.0 34.0 0.097 11.9 23.6 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CBK19907.2 - 0.045 11.7 25.4 0.074 11.0 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CBK19907.2 - 0.079 12.3 26.0 0.16 11.3 18.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CBK19907.2 - 0.33 10.9 15.0 1.1 9.2 10.4 1.9 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 CBK19907.2 - 0.37 10.2 10.8 0.81 9.0 7.5 1.6 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 CBK19907.2 - 0.46 9.4 31.6 0.045 12.8 17.9 2.0 2 0 0 2 2 2 0 BUD22 Astro_capsid PF03115.9 CBK19907.2 - 0.63 8.2 10.1 1 7.5 7.0 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CobT PF06213.7 CBK19907.2 - 0.95 8.5 41.8 1.9 7.5 29.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.6 CBK19907.2 - 1.7 8.1 34.9 4.6 6.7 24.2 1.7 1 0 0 1 1 1 0 PPP4R2 CENP-T PF15511.1 CBK19907.2 - 1.7 7.7 24.4 2.9 7.0 16.9 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T UCH PF00443.24 CBK19908.2 - 8.4e-17 61.1 0.0 1.1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK19908.2 - 4.7e-07 29.5 0.0 7.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TRAPPC-Trs85 PF12739.2 CBK19909.2 - 1.3e-35 122.8 2.9 2.4e-35 122.0 2.0 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Transglut_C PF00927.17 CBK19909.2 - 0.023 14.7 0.0 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain MORN PF02493.15 CBK19910.2 - 1.3e-11 43.4 6.2 0.0078 15.8 0.9 5.5 5 0 0 5 5 5 4 MORN repeat Reo_sigmaC PF04582.7 CBK19912.2 - 0.055 12.6 17.8 0.023 13.9 10.6 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 CBK19912.2 - 0.079 11.9 30.3 0.041 12.9 13.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 CBK19912.2 - 0.12 11.0 25.2 0.089 11.4 16.0 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 CBK19912.2 - 0.17 11.4 39.5 0.85 9.1 26.4 2.2 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 CBK19912.2 - 0.34 8.1 26.8 0.46 7.7 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lge1 PF11488.3 CBK19912.2 - 0.36 11.0 23.2 0.56 10.4 7.5 2.8 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 LsmAD PF06741.8 CBK19912.2 - 1 9.5 4.6 0.46 10.6 0.9 2.2 2 0 0 2 2 1 0 LsmAD domain Laminin_II PF06009.7 CBK19912.2 - 1.1 8.9 22.6 7 6.4 9.1 2.3 1 1 1 2 2 2 0 Laminin Domain II CENP-Q PF13094.1 CBK19912.2 - 1.4 8.9 34.5 0.24 11.4 11.8 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 CBK19912.2 - 1.8 7.6 25.8 0.46 9.6 3.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 CBK19912.2 - 2.7 7.3 27.7 0.46 9.8 8.8 2.2 1 1 1 2 2 2 0 Intermediate filament protein Seryl_tRNA_N PF02403.17 CBK19912.2 - 2.8 7.9 19.9 8.3 6.4 1.6 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CBK19912.2 - 2.8 8.0 24.2 0.88 9.6 9.1 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 CBK19912.2 - 4.7 7.2 24.9 1.9 8.5 9.6 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 CBK19912.2 - 5.9 6.7 35.2 1 9.2 9.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 CBK19912.2 - 6.7 6.5 30.9 1.1 9.1 4.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 CBK19912.2 - 7.9 5.9 24.9 11 5.5 8.0 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 CBK19912.2 - 9.6 6.0 33.5 4.3 7.1 8.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_S13 PF00416.17 CBK19913.2 - 6.4e-23 81.2 0.2 7.4e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF3597 PF12200.3 CBK19914.2 - 0.0028 18.0 0.1 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3597) DivIC PF04977.10 CBK19914.2 - 0.2 11.1 15.1 0.82 9.2 0.2 3.8 3 1 1 4 4 4 0 Septum formation initiator ATG16 PF08614.6 CBK19914.2 - 0.72 9.6 22.7 1.3 8.8 8.9 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) PP2C PF00481.16 CBK19915.2 - 1.1e-29 103.5 0.1 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C MMR_HSR1 PF01926.18 CBK19917.2 - 6.9e-25 87.2 0.0 1.4e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 CBK19917.2 - 4.3e-20 71.9 2.5 3.2e-15 56.1 0.3 2.6 2 1 1 3 3 3 2 GTP1/OBG FeoB_N PF02421.13 CBK19917.2 - 2.5e-14 52.8 0.0 4.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CBK19917.2 - 8.1e-08 31.7 0.0 2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK19917.2 - 9.6e-05 21.8 0.0 0.37 10.1 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBK19917.2 - 0.00029 19.7 0.2 0.0066 15.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CBK19917.2 - 0.0012 19.3 0.0 0.0035 17.8 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBK19917.2 - 0.0039 16.6 0.0 0.021 14.2 0.0 2.1 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 CBK19917.2 - 0.0062 16.3 1.3 1.5 8.5 0.0 2.7 2 1 1 3 3 3 2 Dynamin family NOG1 PF06858.9 CBK19917.2 - 0.0093 15.8 0.2 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Topoisom_I_N PF02919.10 CBK19918.2 - 0.63 9.2 5.9 1 8.5 4.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Adap_comp_sub PF00928.16 CBK19919.2 - 2.1e-82 276.2 0.0 2.6e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK19919.2 - 2.9e-09 36.7 0.2 5.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF788 PF05620.6 CBK19920.2 - 1e-11 44.9 0.3 1.3e-11 44.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) SHP PF03579.8 CBK19920.2 - 0.72 9.2 3.5 1.2 8.5 2.5 1.5 1 0 0 1 1 1 0 Small hydrophobic protein PAP2 PF01569.16 CBK19921.2 - 4.5e-21 74.8 5.7 6.8e-21 74.2 2.5 2.1 2 1 0 2 2 2 1 PAP2 superfamily CDC27 PF09507.5 CBK19922.2 - 8.9 5.4 54.8 0.28 10.3 19.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 IMS PF00817.15 CBK19923.2 - 2.8e-35 121.3 0.0 4.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBK19923.2 - 2.4e-05 24.2 0.1 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Cdd1 PF11731.3 CBK19923.2 - 0.016 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus HHH_5 PF14520.1 CBK19923.2 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain BRCT PF00533.21 CBK19924.2 - 0.0017 18.4 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBK19924.2 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 twin BRCT domain CVNH PF08881.5 CBK19924.2 - 0.033 14.4 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 CVNH domain KH_1 PF00013.24 CBK19926.2 - 5e-08 32.4 0.9 1e-07 31.4 0.6 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBK19926.2 - 0.00042 19.8 2.0 0.0013 18.3 1.4 1.9 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 CBK19926.2 - 0.0011 18.8 1.8 0.0017 18.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CBK19926.2 - 0.061 13.0 1.4 0.16 11.7 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_2 PF13240.1 CBK19926.2 - 0.076 12.5 0.2 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain RNase_H2_suC PF08615.6 CBK19927.2 - 3.9e-13 49.4 0.1 1.8e-12 47.2 0.1 1.8 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cpn60_TCP1 PF00118.19 CBK19928.2 - 3.8e-138 461.1 6.7 4.3e-138 460.9 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MORN PF02493.15 CBK19929.2 - 2.7e-05 23.6 16.8 0.023 14.4 0.3 5.3 4 1 1 5 5 5 3 MORN repeat LRR_8 PF13855.1 CBK19929.2 - 0.0075 15.9 8.0 0.39 10.5 0.1 3.7 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CBK19929.2 - 0.16 11.6 6.9 6.8 6.4 1.2 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Thr_synth_N PF14821.1 CBK19930.2 - 1.6e-22 79.3 0.0 3.7e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 Threonine synthase N terminus Carboxyl_trans PF01039.17 CBK19931.2 - 6.9e-191 634.8 0.1 8.2e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK19931.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) PE-PPE PF08237.6 CBK19932.2 - 0.67 9.3 2.7 20 4.4 1.9 2.1 1 1 0 1 1 1 0 PE-PPE domain THRAP3_BCLAF1 PF15440.1 CBK19932.2 - 2.3 6.7 18.6 3.1 6.3 12.9 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Perilipin PF03036.11 CBK19932.2 - 4.9 5.8 10.8 0.03 13.1 0.9 2.0 2 1 1 3 3 3 0 Perilipin family Ribosomal_L13e PF01294.13 CBK19933.2 - 9.3e-40 135.9 0.2 1.3e-39 135.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e SIR2 PF02146.12 CBK19934.2 - 1.1e-55 188.1 0.0 4.5e-55 186.1 0.0 1.8 2 0 0 2 2 2 1 Sir2 family IF-2B PF01008.12 CBK19935.2 - 0.015 14.3 0.1 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family RPT PF13446.1 CBK19935.2 - 0.015 14.6 0.1 0.036 13.4 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein FdsD PF11390.3 CBK19935.2 - 0.072 13.1 0.3 4.9 7.3 0.1 3.0 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD LETM1 PF07766.8 CBK19937.2 - 5e-50 170.0 0.0 9.1e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein YL1 PF05764.8 CBK19938.2 - 1.7e-08 34.4 14.4 2.7e-08 33.7 10.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein zf-HIT PF04438.11 CBK19938.2 - 7e-05 22.3 2.6 0.00028 20.4 0.2 2.3 2 0 0 2 2 2 1 HIT zinc finger Alba PF01918.16 CBK19938.2 - 0.38 10.3 2.4 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 Alba Vps39_2 PF10367.4 CBK19939.2 - 3.1e-17 62.7 3.0 3.7e-17 62.4 0.9 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CBK19939.2 - 1.3e-09 38.0 0.0 5e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 CBK19939.2 - 0.00035 20.1 0.1 0.049 13.2 0.0 3.2 4 0 0 4 4 4 1 Region in Clathrin and VPS PPR PF01535.15 CBK19939.2 - 0.0008 19.2 0.0 0.21 11.6 0.0 3.7 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 CBK19939.2 - 0.014 15.5 0.4 3.5 8.1 0.0 3.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBK19939.2 - 0.015 15.2 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family Ribosomal_L23 PF00276.15 CBK19940.2 - 5.2e-17 61.5 2.2 1.2e-16 60.4 1.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 MFS_1 PF07690.11 CBK19941.2 - 5.7e-10 38.4 35.0 1.8e-08 33.4 8.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1624 PF07786.7 CBK19941.2 - 0.084 12.1 2.4 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) DmpG_comm PF07836.6 CBK19941.2 - 0.14 11.5 0.1 0.39 10.1 0.1 1.7 1 0 0 1 1 1 0 DmpG-like communication domain TBP PF00352.16 CBK19942.2 - 3.2e-59 196.2 0.1 9.2e-30 101.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CBK19942.2 - 2.1e-07 30.9 0.0 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF3793 PF12672.2 CBK19942.2 - 0.057 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) ADH_zinc_N PF00107.21 CBK19943.2 - 1.7e-16 59.9 0.6 1.2e-15 57.2 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBK19943.2 - 4.6e-11 42.4 0.0 8.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CBK19943.2 - 0.13 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Synaptobrevin PF00957.16 CBK19944.2 - 1.9e-30 104.3 2.1 1.9e-30 104.3 1.4 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 CBK19944.2 - 3.3e-23 81.0 0.3 4.9e-23 80.4 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nyv1_N PF09426.5 CBK19944.2 - 0.015 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal OppC_N PF12911.2 CBK19944.2 - 0.15 11.4 2.2 0.28 10.6 1.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C 4HB_MCP_1 PF12729.2 CBK19944.2 - 0.33 10.2 4.6 4.8 6.4 0.0 3.0 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction DUF3753 PF12575.3 CBK19944.2 - 1.2 9.0 6.8 0.79 9.5 2.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) DUF3154 PF11351.3 CBK19945.2 - 0.94 9.2 6.1 0.78 9.4 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) TPR_11 PF13414.1 CBK19946.2 - 1.9e-14 53.0 19.4 1.7e-09 37.2 2.6 5.5 4 2 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 CBK19946.2 - 8.6e-12 44.0 17.2 5.6e-05 22.7 0.2 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK19946.2 - 1.1e-09 38.0 9.1 0.0055 17.2 0.7 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK19946.2 - 2.1e-09 37.7 12.0 2.5e-06 27.9 2.7 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBK19946.2 - 2.8e-09 36.1 14.5 2e-05 24.0 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK19946.2 - 1.2e-08 34.0 4.4 0.0026 17.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK19946.2 - 1.8e-08 34.5 11.8 1.3e-06 28.6 2.8 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK19946.2 - 1.5e-07 31.1 2.0 1.1e-06 28.3 1.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK19946.2 - 2.4e-07 30.5 9.8 0.00033 20.4 0.7 4.1 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 CBK19946.2 - 5.9e-06 26.1 15.8 0.00013 21.7 0.8 4.3 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBK19946.2 - 0.00016 21.2 1.5 2.9 7.9 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK19946.2 - 0.0016 18.5 6.5 15 6.1 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK19946.2 - 0.0017 18.7 6.0 2.1 8.9 0.1 4.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_18 PF13512.1 CBK19946.2 - 0.008 16.1 3.1 0.11 12.5 0.7 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK19946.2 - 0.029 14.4 23.7 0.03 14.4 3.7 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP_bind_4 PF01902.12 CBK19947.2 - 1.2e-40 139.1 0.0 2.8e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region DUF601 PF04642.7 CBK19947.2 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 tRNA_Me_trans PF03054.11 CBK19947.2 - 0.05 12.1 0.1 0.14 10.6 0.0 1.7 2 0 0 2 2 2 0 tRNA methyl transferase KH_1 PF00013.24 CBK19949.2 - 4e-39 132.0 18.4 9.6e-16 57.1 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CBK19949.2 - 2.9e-28 96.9 18.0 2.8e-10 39.6 0.2 4.1 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 CBK19949.2 - 3.5e-08 32.9 2.5 0.075 12.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBK19949.2 - 4.6e-07 29.3 12.4 0.0036 16.8 0.2 4.0 1 1 1 3 3 3 3 KH domain KH_5 PF13184.1 CBK19949.2 - 1.4e-05 24.8 3.0 1.2 9.0 0.1 3.7 3 0 0 3 3 3 3 NusA-like KH domain Band_7 PF01145.20 CBK19951.2 - 1.1e-16 61.2 0.1 2.2e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Imm41 PF15583.1 CBK19951.2 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 41 Band_7_1 PF13421.1 CBK19951.2 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family NGP1NT PF08153.7 CBK19952.2 - 8.1e-41 139.0 0.3 8.1e-41 139.0 0.2 2.0 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBK19952.2 - 1e-19 70.6 0.6 8.6e-16 57.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK19952.2 - 3.5e-06 26.3 0.2 3.1e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 CBK19952.2 - 0.00019 20.6 0.0 0.00045 19.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBK19952.2 - 0.0021 17.5 0.2 0.3 10.4 0.0 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CBK19952.2 - 0.0035 16.6 0.6 0.19 10.9 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBK19952.2 - 0.0077 16.7 0.7 3.6 8.0 0.2 2.8 2 0 0 2 2 2 2 Miro-like protein cobW PF02492.14 CBK19952.2 - 0.04 13.3 0.2 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CBK19952.2 - 0.39 10.5 10.9 4.8 6.9 3.3 4.3 2 2 0 2 2 2 0 Dynamin family Vmethyltransf_C PF08456.5 CBK19952.2 - 7.5 5.8 11.1 0.23 10.8 0.1 2.4 2 0 0 2 2 2 0 Viral methyltransferase C-terminal Ribosomal_L36e PF01158.13 CBK19953.2 - 1.6e-24 85.7 5.5 1.9e-24 85.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dak2 PF02734.12 CBK19953.2 - 0.043 13.4 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain ArfGap PF01412.13 CBK19953.2 - 0.084 12.6 1.5 0.12 12.1 0.9 1.3 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf D5_N PF08706.6 CBK19953.2 - 0.27 11.3 1.7 0.3 11.1 1.2 1.1 1 0 0 1 1 1 0 D5 N terminal like CENP-H PF05837.7 CBK19953.2 - 0.81 9.8 4.8 2.2 8.4 0.8 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ribosomal_L13e PF01294.13 CBK19954.2 - 1.7e-34 118.8 0.3 1.3e-33 115.9 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L13e HSP70 PF00012.15 CBK19955.2 - 9.9e-76 254.9 0.0 1.4e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK19955.2 - 4.2e-13 48.5 0.0 1.3e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 CBK19955.2 - 0.082 11.7 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain tRNA-synt_2b PF00587.20 CBK19956.2 - 1.4e-37 128.9 0.1 2.1e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBK19956.2 - 2.1e-24 85.5 4.6 4.1e-24 84.6 3.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.6 CBK19956.2 - 0.26 10.0 4.7 0.42 9.3 3.3 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein IncA PF04156.9 CBK19956.2 - 0.72 9.4 2.5 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein RRM_1 PF00076.17 CBK19957.2 - 6.7e-11 41.6 0.0 1.9e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19957.2 - 0.00015 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19957.2 - 0.0059 16.4 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Patatin PF01734.17 CBK19958.2 - 2.3e-15 57.0 2.5 2.3e-13 50.5 1.7 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase zf-DHHC PF01529.15 CBK19959.2 - 9.9e-22 77.1 15.2 9.9e-22 77.1 10.6 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF35_N PF12172.3 CBK19959.2 - 0.063 13.2 3.6 0.063 13.2 2.5 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) C1_1 PF00130.17 CBK19959.2 - 0.78 9.5 13.9 3.3 7.5 6.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 CBK19959.2 - 6.7 6.6 12.7 6 6.7 6.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBK19959.2 - 8.1 6.0 8.6 10 5.7 4.4 2.3 2 1 0 2 2 2 0 zinc-ribbon domain AAA PF00004.24 CBK19960.2 - 5e-38 130.2 0.4 1.2e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBK19960.2 - 1.9e-07 31.1 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBK19960.2 - 2.8e-06 27.0 0.5 7.6e-05 22.4 0.0 3.2 2 2 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBK19960.2 - 4e-06 26.9 2.3 0.00021 21.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBK19960.2 - 1.3e-05 25.3 2.1 0.0002 21.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBK19960.2 - 7.1e-05 21.9 0.1 0.00074 18.6 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBK19960.2 - 0.00013 22.7 0.5 0.0004 21.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBK19960.2 - 0.00029 20.6 1.1 0.28 10.8 0.0 3.0 2 1 1 3 3 3 2 Archaeal ATPase AAA_24 PF13479.1 CBK19960.2 - 0.00039 20.0 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK19960.2 - 0.0005 18.9 0.6 0.02 13.6 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBK19960.2 - 0.00093 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBK19960.2 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBK19960.2 - 0.0015 18.0 0.1 0.0089 15.5 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBK19960.2 - 0.0016 18.3 0.0 0.0047 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBK19960.2 - 0.0034 16.5 0.1 0.022 13.8 0.0 2.2 2 1 0 2 2 2 1 KaiC AAA_19 PF13245.1 CBK19960.2 - 0.0047 16.6 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 CBK19960.2 - 0.0074 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CBK19960.2 - 0.0087 15.2 0.0 0.021 13.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBK19960.2 - 0.0088 16.2 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 CBK19960.2 - 0.011 16.0 0.3 0.027 14.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain CCDC155 PF14662.1 CBK19960.2 - 0.021 14.4 1.5 0.021 14.4 1.0 2.0 3 0 0 3 3 2 0 Coiled-coil region of CCDC155 PhoH PF02562.11 CBK19960.2 - 0.04 13.1 0.1 0.09 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 CBK19960.2 - 0.043 13.4 0.0 0.099 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBK19960.2 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBK19960.2 - 0.068 12.0 0.1 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MutS_IV PF05190.13 CBK19960.2 - 0.082 13.0 0.3 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 MutS family domain IV Sigma54_activ_2 PF14532.1 CBK19960.2 - 0.093 12.7 0.0 0.42 10.6 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 CBK19960.2 - 0.095 11.6 0.3 0.67 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 CBK19960.2 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 CBK19960.2 - 0.12 12.5 0.8 1.8 8.8 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NACHT PF05729.7 CBK19960.2 - 0.25 11.0 1.2 1.3 8.6 0.1 2.6 2 1 0 2 2 2 0 NACHT domain FlxA PF14282.1 CBK19960.2 - 0.48 10.3 3.5 3.1 7.7 1.2 2.3 2 0 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.6 CBK19960.2 - 0.77 9.1 3.3 6.9 6.0 0.1 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 HSP70 PF00012.15 CBK19961.2 - 7.5e-11 40.6 0.0 1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein tRNA-synt_2b PF00587.20 CBK19962.2 - 1.4e-37 128.9 0.1 2.1e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBK19962.2 - 9.2e-19 67.4 1.8 1.7e-18 66.5 1.3 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MBOAT PF03062.14 CBK19963.2 - 0.0012 18.0 0.7 0.0012 18.0 0.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Grp1_Fun34_YaaH PF01184.14 CBK19963.2 - 0.0049 16.1 1.1 0.005 16.1 0.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PI31_Prot_C PF08577.6 CBK19964.2 - 0.29 11.8 8.2 1.1 9.9 5.7 2.0 1 1 0 1 1 1 0 PI31 proteasome regulator PNRC PF15365.1 CBK19964.2 - 0.66 10.0 0.2 0.66 10.0 0.1 2.4 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator VHS PF00790.14 CBK19965.2 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain CSD PF00313.17 CBK19969.2 - 0.026 14.2 0.1 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Phage_stabilise PF11134.3 CBK19969.2 - 0.056 12.0 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein Mso1_C PF14477.1 CBK19969.2 - 0.15 12.3 5.2 0.28 11.5 2.8 1.9 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 RRM_1 PF00076.17 CBK19970.2 - 2.2e-66 219.4 0.1 5.9e-19 67.4 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK19970.2 - 1.7e-51 172.1 0.0 1.6e-15 56.7 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK19970.2 - 2.6e-34 116.8 0.0 1.1e-10 41.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK19970.2 - 9.4e-05 22.0 0.1 1.4 8.6 0.0 4.6 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 CBK19970.2 - 0.00037 20.2 0.0 1.1 9.1 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBK19970.2 - 0.0013 18.5 0.7 0.85 9.5 0.0 4.0 4 1 0 4 4 4 1 RNA binding motif RNA_bind PF08675.6 CBK19970.2 - 0.0049 16.8 0.0 0.93 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA binding domain Ish1 PF10281.4 CBK19970.2 - 0.011 15.7 0.1 50 4.0 0.0 3.9 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein CDC45 PF02724.9 CBK19970.2 - 2.1 6.2 18.6 3.7 5.4 0.4 2.1 2 0 0 2 2 2 0 CDC45-like protein RRM_6 PF14259.1 CBK19971.2 - 2.7e-09 36.8 0.0 4.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK19971.2 - 3.5e-05 23.3 0.0 9.5e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAM2 PF07145.10 CBK19971.2 - 0.064 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RRM_5 PF13893.1 CBK19971.2 - 0.15 11.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 CBK19971.2 - 0.16 11.6 0.6 0.29 10.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S9 PF00380.14 CBK19972.2 - 4.4e-35 120.5 0.4 5e-35 120.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 CBK19972.2 - 0.034 11.6 0.0 0.039 11.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Peptidase_M1 PF01433.15 CBK19973.2 - 1.7e-09 37.3 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 DinI PF06183.8 CBK19976.2 - 0.016 15.2 0.1 0.029 14.3 0.0 1.5 2 0 0 2 2 2 0 DinI-like family TP_methylase PF00590.15 CBK19976.2 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2271 PF10029.4 CBK19976.2 - 0.056 12.9 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) DJ-1_PfpI PF01965.19 CBK19977.2 - 1.5e-33 115.3 0.3 1.8e-33 115.0 0.2 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CBK19977.2 - 1.7e-15 56.6 0.0 2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 CBK19977.2 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain ELFV_dehydrog PF00208.16 CBK19977.2 - 0.057 12.9 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1154 PF06631.6 CBK19977.2 - 0.098 12.3 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) LRR_8 PF13855.1 CBK19978.2 - 8.2e-05 22.2 2.7 0.0023 17.6 0.2 3.5 1 1 2 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 CBK19978.2 - 0.0021 17.6 0.8 2.1 8.0 0.2 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF563 PF04577.9 CBK19979.2 - 5.4e-17 62.3 0.0 6.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Proteasome PF00227.21 CBK19980.2 - 4.1e-31 107.7 0.1 5.6e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.23 CBK19981.2 - 3.2e-43 147.4 0.1 4e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NTPase_I-T PF01931.13 CBK19982.2 - 1.3e-44 151.8 0.0 1.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF84 Sec63 PF02889.11 CBK19983.2 - 9.5e-32 110.4 2.9 1.3e-31 109.9 2.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CBK19983.2 - 1.3e-18 66.5 0.2 2.7e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Pmp3 PF01679.12 CBK19983.2 - 0.09 12.4 4.1 3.1 7.5 0.2 2.6 2 0 0 2 2 2 0 Proteolipid membrane potential modulator DUF4064 PF13273.1 CBK19983.2 - 1.2 9.2 7.0 2.4 8.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.1 CBK19983.2 - 5.5 7.4 7.1 2.6 8.5 0.0 3.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain ER_lumen_recept PF00810.13 CBK19984.2 - 4.4e-23 82.4 3.6 4.4e-23 82.4 2.5 2.7 3 0 0 3 3 3 1 ER lumen protein retaining receptor 6PGD PF00393.14 CBK19986.2 - 2.6e-45 154.8 0.0 3.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBK19986.2 - 1.2e-18 67.5 0.0 2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase EF-hand_7 PF13499.1 CBK19987.2 - 4.3e-06 26.7 0.2 0.084 13.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBK19987.2 - 0.0029 17.3 2.7 0.81 9.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBK19987.2 - 0.016 14.4 2.1 0.31 10.4 0.1 2.3 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 CBK19987.2 - 0.076 13.0 0.0 7 6.7 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 CBK19987.2 - 0.12 11.7 0.2 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 EF hand IncA PF04156.9 CBK19988.2 - 0.0039 16.8 12.3 0.0039 16.8 8.5 5.1 1 1 3 4 4 4 1 IncA protein Reo_sigmaC PF04582.7 CBK19988.2 - 0.11 11.7 41.9 0.029 13.5 2.3 4.4 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Bcr-Abl_Oligo PF09036.5 CBK19988.2 - 0.12 12.3 12.3 0.16 11.9 0.2 4.2 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain PRELI PF04707.9 CBK19989.2 - 5.6e-29 100.7 0.0 6.5e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family PRELI PF04707.9 CBK19990.2 - 2.4e-24 85.6 0.1 3e-24 85.3 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family EF-hand_1 PF00036.27 CBK19991.2 - 1.4e-34 114.7 11.6 1.8e-08 33.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBK19991.2 - 2e-32 111.1 8.2 3.9e-16 58.9 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK19991.2 - 2.6e-27 92.9 11.0 1.4e-07 30.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBK19991.2 - 3.7e-27 93.7 10.7 5.8e-13 48.2 0.2 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBK19991.2 - 9.7e-27 90.4 4.0 9e-08 31.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.1 CBK19991.2 - 2.1e-13 49.9 0.4 1.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBK19991.2 - 3.6e-13 49.5 1.5 1.9e-06 27.8 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBK19991.2 - 5.8e-08 32.4 5.9 0.0015 18.1 0.4 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CBK19991.2 - 5.5e-07 29.1 0.1 0.002 17.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 CBK19991.2 - 3.6e-05 23.5 0.5 0.016 14.9 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CBK19991.2 - 0.00011 21.7 0.0 0.25 10.9 0.0 2.4 1 1 0 2 2 2 2 Caleosin related protein EFhand_Ca_insen PF08726.5 CBK19991.2 - 0.0015 18.4 1.8 0.057 13.3 0.1 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.11 CBK19991.2 - 0.0053 16.7 0.6 3 7.8 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb4 Toprim PF01751.17 CBK19991.2 - 0.0056 16.6 0.1 0.14 12.1 0.1 2.5 1 1 0 1 1 1 1 Toprim domain DUF2267 PF10025.4 CBK19991.2 - 0.022 14.8 0.0 0.037 14.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF533 PF04391.7 CBK19991.2 - 0.04 13.2 2.0 5.4 6.3 0.1 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF533) DUF1007 PF06226.8 CBK19991.2 - 0.042 13.5 1.8 0.73 9.5 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1007) OB_RNB PF08206.6 CBK19991.2 - 0.043 13.3 0.1 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain MotA_activ PF09114.5 CBK19991.2 - 0.049 13.3 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Adenine_glyco PF03352.8 CBK19991.2 - 0.15 11.5 1.1 2.9 7.3 0.0 2.1 1 1 1 2 2 2 0 Methyladenine glycosylase RloB PF13707.1 CBK19991.2 - 0.29 10.7 6.7 1.4 8.5 1.0 2.3 1 1 1 2 2 2 0 RloB-like protein Toprim_2 PF13155.1 CBK19991.2 - 0.49 10.7 2.7 18 5.7 0.2 2.9 1 1 2 3 3 3 0 Toprim-like Ribosomal_L36e PF01158.13 CBK19992.2 - 1.6e-24 85.7 5.5 1.9e-24 85.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dak2 PF02734.12 CBK19992.2 - 0.043 13.4 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain ArfGap PF01412.13 CBK19992.2 - 0.084 12.6 1.5 0.12 12.1 0.9 1.3 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf D5_N PF08706.6 CBK19992.2 - 0.27 11.3 1.7 0.3 11.1 1.2 1.1 1 0 0 1 1 1 0 D5 N terminal like CENP-H PF05837.7 CBK19992.2 - 0.81 9.8 4.8 2.2 8.4 0.8 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Ribosomal_L13e PF01294.13 CBK19993.2 - 1.7e-34 118.8 0.3 1.3e-33 115.9 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L13e SecE PF00584.15 CBK19994.2 - 1e-13 50.6 0.0 1.2e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Acetyltransf_7 PF13508.1 CBK19995.2 - 6.1e-10 39.1 0.0 9.1e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBK19995.2 - 1.5e-08 34.7 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK19995.2 - 4.2e-07 29.8 0.0 4.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CBK19995.2 - 0.00047 20.0 0.0 0.036 13.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBK19995.2 - 0.00054 20.1 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK19995.2 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBK19995.2 - 0.11 12.3 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Het-C PF07217.6 CBK19997.2 - 0.071 11.2 0.5 0.078 11.1 0.3 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Oxygenase-NA PF09859.4 CBK19997.2 - 0.11 11.8 0.4 0.28 10.4 0.2 1.6 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA Cnd1_N PF12922.2 CBK19997.2 - 0.19 11.3 1.6 0.22 11.1 1.1 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NIF3 PF01784.13 CBK19998.2 - 2.9e-51 174.4 0.0 3.4e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) OTU PF02338.14 CBK19999.2 - 2e-11 44.5 0.0 3.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBK19999.2 - 0.00042 19.7 0.2 0.014 14.7 0.0 2.0 1 1 1 2 2 2 2 Peptidase C65 Otubain Adaptin_N PF01602.15 CBK20000.2 - 2.1e-75 254.0 12.3 2.1e-75 254.0 8.6 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 CBK20000.2 - 1.8e-09 37.7 6.7 9.3e-08 32.1 0.7 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK20000.2 - 1.2e-06 28.6 0.9 0.00023 21.3 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CBK20000.2 - 9.3e-06 25.3 3.0 0.16 12.0 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CBK20000.2 - 0.00029 21.1 1.1 0.092 13.1 0.1 3.6 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBK20000.2 - 0.0019 18.0 5.7 0.0047 16.7 0.4 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CBK20000.2 - 0.0046 17.3 0.1 0.0046 17.3 0.0 4.7 5 2 1 6 6 6 2 HEAT-like repeat Arm PF00514.18 CBK20000.2 - 0.094 12.5 0.3 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Histone PF00125.19 CBK20002.2 - 7.6e-33 112.4 0.5 1.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK20002.2 - 5.8e-05 23.1 0.1 8.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20002.2 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK20003.2 - 9.7e-15 54.4 0.1 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBK20003.2 - 6e-05 22.9 0.1 8.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CBK20003.2 - 8.1e-05 22.7 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20003.2 - 0.00075 19.5 0.1 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBK20003.2 - 0.016 14.9 0.1 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HTH_17 PF12728.2 CBK20003.2 - 0.048 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-31kDa PF02291.10 CBK20003.2 - 0.07 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 CBK20003.2 - 0.15 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CLPTM1 PF05602.7 CBK20004.2 - 3.1e-119 398.5 4.0 4.5e-119 398.0 2.8 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CBK20004.2 - 0.00029 20.3 3.8 0.11 12.0 0.6 2.7 2 0 0 2 2 2 2 PQ loop repeat Glyco_transf_49 PF13896.1 CBK20005.2 - 0.00012 21.2 0.1 0.00012 21.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Ribosomal_S27e PF01667.12 CBK20006.2 - 0.59 9.7 4.4 0.31 10.6 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein S27 Transketolase_N PF00456.16 CBK20007.2 - 1.6e-128 428.2 0.0 2.1e-128 427.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CBK20007.2 - 3.7e-41 140.5 0.0 7.6e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBK20007.2 - 2.5e-12 46.7 0.1 5.3e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CBK20007.2 - 5.3e-06 25.5 0.0 0.00011 21.2 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CBK20007.2 - 0.015 14.0 0.0 0.03 13.0 0.0 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF498 PF04430.9 CBK20007.2 - 0.048 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Kelch_1 PF01344.20 CBK20007.2 - 2.5 7.7 4.6 63 3.2 0.2 3.4 3 0 0 3 3 3 0 Kelch motif Choline_kinase PF01633.15 CBK20008.2 - 1.1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBK20008.2 - 1.1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CBK20008.2 - 0.15 11.2 0.1 1.8 7.6 0.0 2.5 3 0 0 3 3 3 0 Protein kinase domain Pkinase PF00069.20 CBK20009.2 - 1.2e-77 260.5 0.0 1.4e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20009.2 - 4.3e-30 104.6 0.0 5.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK20009.2 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CBK20009.2 - 0.02 13.9 0.1 0.034 13.2 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDK PF00334.14 CBK20010.2 - 7.4e-57 190.8 0.0 8.4e-57 190.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase LNS2 PF08235.8 CBK20011.2 - 4.2e-55 185.6 0.0 5.6e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) HAD PF12710.2 CBK20011.2 - 0.057 13.5 0.0 0.085 13.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA_bind PF01588.15 CBK20012.2 - 1e-28 99.0 0.0 4.6e-28 96.8 0.0 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain zf-C2H2_2 PF12756.2 CBK20013.2 - 2.3e-21 75.7 1.8 6.1e-21 74.4 1.3 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) HSP90 PF00183.13 CBK20013.2 - 0.12 10.7 0.8 0.16 10.3 0.6 1.1 1 0 0 1 1 1 0 Hsp90 protein Clp1 PF06807.9 CBK20014.2 - 5e-11 42.7 0.0 9.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CBK20014.2 - 0.15 11.7 0.1 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Metallophos PF00149.23 CBK20015.2 - 1.4e-40 138.8 0.0 1.7e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK20015.2 - 0.00017 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 60KD_IMP PF02096.15 CBK20016.2 - 1.6e-47 161.7 0.1 3e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein POM121 PF15229.1 CBK20016.2 - 0.14 11.5 0.3 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 POM121 family Glutaredoxin PF00462.19 CBK20017.2 - 5.2e-13 48.7 0.0 8.1e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CBK20017.2 - 0.031 14.5 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EST1_DNA_bind PF10373.4 CBK20018.2 - 2.6e-24 85.9 1.5 3.9e-24 85.3 1.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_17 PF13431.1 CBK20018.2 - 0.00012 22.0 0.0 0.00069 19.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat EST1 PF10374.4 CBK20018.2 - 0.00012 22.0 10.1 0.07 13.1 0.9 4.0 3 1 1 4 4 4 2 Telomerase activating protein Est1 TPR_11 PF13414.1 CBK20018.2 - 0.00057 19.4 0.7 0.0015 18.0 0.5 1.7 1 0 0 1 1 1 1 TPR repeat Usp PF00582.21 CBK20019.2 - 1.7e-15 57.4 0.0 4.3e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family Aminotran_1_2 PF00155.16 CBK20020.2 - 1e-58 199.0 0.0 1.3e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_5 PF14501.1 CBK20020.2 - 0.0065 16.1 0.1 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Romo1 PF10247.4 CBK20020.2 - 0.012 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Ribosomal_L5_C PF00673.16 CBK20021.2 - 6.4e-22 77.1 0.1 1.3e-21 76.1 0.0 1.5 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBK20021.2 - 3.3e-19 68.4 0.7 1e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Peptidase_A22B PF04258.8 CBK20022.2 - 4.5e-30 105.1 21.6 6.4e-27 94.7 7.5 2.0 1 1 1 2 2 2 2 Signal peptide peptidase Tubulin PF00091.20 CBK20023.2 - 1.7e-71 240.4 0.1 2.6e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK20023.2 - 1.9e-43 147.4 0.1 3.2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBK20023.2 - 7.6e-08 32.4 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBK20023.2 - 0.035 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Glyco_hydro_18 PF00704.23 CBK20024.2 - 3.7e-97 325.8 4.1 5.3e-97 325.3 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ish1 PF10281.4 CBK20024.2 - 3.3 7.8 4.4 0.79 9.8 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF563 PF04577.9 CBK20025.2 - 5.4e-17 62.3 0.0 6.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Proteasome PF00227.21 CBK20026.2 - 4.4e-31 107.6 0.1 5.6e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.23 CBK20027.2 - 9.2e-44 149.2 0.1 1.2e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Dimer_Tnp_hAT PF05699.9 CBK20028.2 - 0.0063 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mito_carr PF00153.22 CBK20029.2 - 3.5e-63 209.3 7.9 2.3e-24 84.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pr_beta_C PF12465.3 CBK20029.2 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Proteasome beta subunits C terminal ER_lumen_recept PF00810.13 CBK20030.2 - 2.6e-25 89.6 6.1 2.6e-25 89.6 4.2 2.7 3 0 0 3 3 3 1 ER lumen protein retaining receptor DUF4131 PF13567.1 CBK20030.2 - 2.3 7.5 15.3 0.22 10.8 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) FH2 PF02181.18 CBK20031.2 - 1.5e-76 257.7 0.0 1.9e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF2360 PF10152.4 CBK20031.2 - 0.0048 17.1 15.3 0.21 11.8 0.1 3.4 3 0 0 3 3 3 3 Predicted coiled-coil domain-containing protein (DUF2360) Acyltransferase PF01553.16 CBK20032.2 - 7.2e-10 38.4 0.0 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NARP1 PF12569.3 CBK20033.2 - 3.3e-93 313.2 11.1 1.8e-92 310.7 2.3 2.7 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CBK20033.2 - 5.5e-07 29.1 17.6 0.032 13.8 1.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_14 PF13428.1 CBK20033.2 - 7.6e-07 29.2 1.8 3.1 8.6 0.0 6.8 8 3 2 10 10 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20033.2 - 1.6e-06 28.6 13.2 0.021 15.5 0.3 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK20033.2 - 4.5e-05 23.6 8.6 0.25 11.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK20033.2 - 0.00017 21.4 1.9 1.9 8.8 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK20033.2 - 0.001 18.6 7.1 1.1 9.2 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBK20033.2 - 0.0023 18.2 0.7 26 5.5 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK20033.2 - 0.0043 16.5 12.7 0.053 13.1 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20033.2 - 0.01 15.7 9.8 1.9 8.4 1.5 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20033.2 - 0.023 14.5 21.3 0.19 11.7 0.2 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Smoothelin PF12510.3 CBK20033.2 - 0.081 12.7 0.1 0.38 10.6 0.1 2.2 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein AF-4 PF05110.8 CBK20033.2 - 4.6 4.9 9.2 6.6 4.4 6.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GTP_EFTU PF00009.22 CBK20034.2 - 7e-57 191.8 0.1 1.3e-56 191.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBK20034.2 - 4e-36 123.2 0.1 2.3e-35 120.7 0.0 2.3 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.1 CBK20034.2 - 2.5e-29 100.9 0.0 5.9e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBK20034.2 - 2.2e-26 91.5 0.1 6.3e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBK20034.2 - 5.1e-12 45.7 0.0 2.1e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK20034.2 - 0.004 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CBK20034.2 - 0.019 14.0 0.1 0.072 12.1 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Methyltransf_31 PF13847.1 CBK20035.2 - 0.0023 17.5 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CBK20035.2 - 0.0024 16.8 0.0 0.0064 15.4 0.0 1.6 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.1 CBK20035.2 - 0.0027 17.4 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBK20035.2 - 0.02 14.5 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 CBK20035.2 - 0.035 13.2 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CBK20035.2 - 0.054 13.9 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LRR_8 PF13855.1 CBK20036.2 - 4.8e-05 23.0 2.2 0.0013 18.4 0.2 3.4 1 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 CBK20036.2 - 0.0013 18.3 0.9 2 8.1 0.0 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DJ-1_PfpI PF01965.19 CBK20037.2 - 1.5e-33 115.3 0.3 1.8e-33 115.0 0.2 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CBK20037.2 - 1.7e-15 56.6 0.0 2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 CBK20037.2 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain ELFV_dehydrog PF00208.16 CBK20037.2 - 0.057 12.9 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1154 PF06631.6 CBK20037.2 - 0.098 12.3 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) TP_methylase PF00590.15 CBK20038.2 - 1.7e-25 89.9 0.0 2.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Peptidase_M1 PF01433.15 CBK20041.2 - 3.1e-12 46.2 0.2 4.4e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 Ank_2 PF12796.2 CBK20042.2 - 5.4e-31 106.7 17.4 6.6e-14 52.0 0.8 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBK20042.2 - 2.1e-22 79.0 2.9 4.2e-09 36.6 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBK20042.2 - 1.2e-19 69.0 9.3 1.6e-06 27.6 0.5 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBK20042.2 - 6.2e-18 64.4 9.1 7.1e-05 22.9 0.1 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK20042.2 - 2.4e-17 61.2 7.8 0.00019 21.3 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Syja_N PF02383.13 CBK20044.2 - 9.9e-60 201.9 0.0 1.1e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain Lyase_1 PF00206.15 CBK20045.2 - 3e-93 312.4 0.0 3.8e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CBK20045.2 - 1.3e-17 63.5 0.0 3.9e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus SspK PF08176.7 CBK20046.2 - 0.018 15.0 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Aa_trans PF01490.13 CBK20047.2 - 2e-21 75.9 17.0 2.2e-21 75.8 11.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF373 PF04123.8 CBK20047.2 - 1.5 7.7 12.2 0.34 9.8 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1212 PF06738.7 CBK20047.2 - 3.3 7.1 8.2 0.1 12.0 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Colicin PF01024.14 CBK20047.2 - 6.1 6.3 5.8 0.74 9.3 1.1 1.6 2 0 0 2 2 2 0 Colicin pore forming domain Sec23_trunk PF04811.10 CBK20049.2 - 4.1e-21 75.4 0.0 6.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 CBK20049.2 - 3e-13 49.1 2.2 7.5e-13 47.8 1.5 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CBK20049.2 - 3.6e-11 42.4 0.1 1.1e-10 40.8 0.1 1.9 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CBK20049.2 - 4.5e-09 36.7 0.0 1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain CRM1_C PF08767.6 CBK20050.2 - 2.2e-05 23.5 3.9 6.7e-05 21.9 2.7 1.9 1 0 0 1 1 1 1 CRM1 C terminal DDE_Tnp_4 PF13359.1 CBK20051.2 - 6e-12 45.4 0.0 9.9e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tsg PF04668.7 CBK20051.2 - 0.011 15.8 0.2 0.032 14.4 0.1 1.8 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region NADH-u_ox-rdase PF10785.4 CBK20052.2 - 2.1e-09 37.4 0.1 2.5e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit BRX PF08381.6 CBK20053.2 - 0.028 13.4 0.0 12 5.0 0.0 4.5 6 0 0 6 6 6 0 Transcription factor regulating root and shoot growth via Pin3 MOZ_SAS PF01853.13 CBK20055.2 - 1.4e-77 259.2 4.2 1.9e-77 258.7 2.9 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2_4 PF13894.1 CBK20055.2 - 0.015 15.6 3.3 0.035 14.4 2.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBK20055.2 - 0.14 12.5 4.3 0.38 11.1 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNAP PF14938.1 CBK20056.2 - 1.2e-15 57.4 12.9 2e-08 33.7 0.8 3.2 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBK20056.2 - 7.8e-10 38.5 12.3 0.00017 21.4 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20056.2 - 0.00018 21.2 17.8 0.002 17.8 1.1 6.3 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK20056.2 - 0.0005 19.6 16.9 0.082 12.5 5.0 4.1 4 1 0 4 4 4 2 TPR repeat PPR_3 PF13812.1 CBK20056.2 - 0.0026 17.9 0.7 0.06 13.6 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_1 PF00515.23 CBK20056.2 - 0.0058 16.1 2.1 0.0058 16.1 1.5 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20056.2 - 0.0076 16.8 8.5 13 6.6 1.4 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20056.2 - 0.042 14.4 11.3 7.1 7.5 0.0 5.4 6 1 0 6 6 5 0 Tetratricopeptide repeat VEFS-Box PF09733.4 CBK20056.2 - 0.044 13.4 1.5 5 6.7 0.1 2.6 2 0 0 2 2 2 0 VEFS-Box of polycomb protein PPR PF01535.15 CBK20056.2 - 0.22 11.5 1.3 4.5 7.4 0.0 3.6 4 0 0 4 4 4 0 PPR repeat TPR_8 PF13181.1 CBK20056.2 - 3.4 7.6 10.7 0.71 9.7 1.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1423 PF07227.6 CBK20057.2 - 0.059 12.0 0.5 0.06 12.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) LSM PF01423.17 CBK20058.2 - 5.2e-15 54.7 0.3 1.2e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 LSM domain Mnd1 PF03962.10 CBK20058.2 - 0.27 10.8 11.1 1.5 8.4 2.4 2.4 2 0 0 2 2 2 0 Mnd1 family DUF3007 PF11460.3 CBK20058.2 - 1.1 9.3 5.9 0.098 12.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) SKIP_SNW PF02731.10 CBK20059.2 - 3.2e-56 189.1 0.3 3.2e-56 189.1 0.2 2.6 2 0 0 2 2 2 1 SKIP/SNW domain Nab1 PF04902.7 CBK20059.2 - 0.13 11.7 6.4 0.086 12.3 1.2 2.5 2 1 0 2 2 2 0 Conserved region in Nab1 Pkinase PF00069.20 CBK20060.2 - 6.2e-58 195.9 0.0 7.7e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20060.2 - 9e-33 113.4 0.0 1.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBK20060.2 - 3e-07 30.5 0.0 4.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CBK20060.2 - 0.0004 19.4 0.0 0.00069 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Nudix_N_2 PF14803.1 CBK20060.2 - 0.076 12.7 3.0 0.36 10.5 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal APH PF01636.18 CBK20060.2 - 0.16 11.7 0.0 6.4 6.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.1 CBK20060.2 - 0.16 12.1 0.5 4.9 7.3 0.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Acetyltransf_1 PF00583.19 CBK20061.2 - 3e-05 23.9 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CBK20061.2 - 0.00091 19.4 0.0 0.0021 18.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK20061.2 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0227 PF05728.7 CBK20061.2 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Bot1p PF12298.3 CBK20062.2 - 3.6e-05 23.7 0.0 3.6e-05 23.7 0.0 3.0 2 2 1 3 3 3 1 Eukaryotic mitochondrial regulator protein HTH_23 PF13384.1 CBK20062.2 - 0.0011 18.5 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CBK20062.2 - 0.043 13.8 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TRAP_alpha PF03896.11 CBK20062.2 - 0.16 10.9 0.0 0.16 10.9 0.0 3.0 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.1 CBK20062.2 - 0.64 8.9 6.5 0.9 8.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 CBK20062.2 - 1 7.5 11.6 1.6 6.8 8.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF874 PF05917.6 CBK20062.2 - 2.7 6.7 12.2 4.5 6.0 8.5 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF2201_N PF13203.1 CBK20062.2 - 7.5 5.6 16.5 33 3.5 10.6 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain THF_DHG_CYH_C PF02882.14 CBK20063.2 - 1.1e-71 239.1 1.0 1.6e-71 238.5 0.7 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBK20063.2 - 1.9e-41 140.7 1.1 3e-41 140.1 0.7 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 CBK20064.2 - 1.3e-08 34.3 0.0 0.0017 18.1 0.0 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.3 CBK20064.2 - 0.0024 16.0 0.1 0.57 8.2 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CBK20064.2 - 0.023 14.1 0.0 5.9 6.2 0.0 2.7 1 1 2 3 3 3 0 PQQ-like domain Coatomer_WDAD PF04053.9 CBK20064.2 - 0.16 10.7 0.1 0.9 8.2 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region HSP70 PF00012.15 CBK20065.2 - 5.5e-27 93.9 0.0 7.2e-26 90.2 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20065.2 - 0.014 14.0 0.6 0.033 12.7 0.4 1.7 1 1 0 1 1 1 0 MreB/Mbl protein StbA PF06406.6 CBK20065.2 - 0.019 13.9 0.2 0.046 12.6 0.1 1.7 2 0 0 2 2 2 0 StbA protein DnaJ PF00226.26 CBK20067.2 - 3.6e-23 81.0 0.7 6.4e-23 80.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBK20067.2 - 1e-22 79.7 0.6 4.3e-20 71.3 0.0 3.1 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBK20067.2 - 2.1e-13 50.1 20.8 7.4e-13 48.3 14.4 2.0 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBK20067.2 - 0.13 11.9 12.2 0.18 11.4 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Epimerase PF01370.16 CBK20068.2 - 1.1e-45 155.9 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBK20068.2 - 1.1e-27 95.7 0.1 1.9e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBK20068.2 - 2.2e-12 46.2 0.0 3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBK20068.2 - 2.2e-11 43.2 0.0 5.7e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CBK20068.2 - 3.8e-11 42.4 0.0 1.6e-09 37.1 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBK20068.2 - 4.4e-09 36.4 0.0 7.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CBK20068.2 - 5e-09 35.4 0.0 7.5e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBK20068.2 - 1.4e-08 34.9 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBK20068.2 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 CBK20068.2 - 0.0061 17.1 0.0 0.11 13.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 CBK20068.2 - 0.0062 15.8 0.0 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Histone PF00125.19 CBK20069.2 - 1.4e-23 82.7 0.1 1.8e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20069.2 - 1.8e-05 24.6 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFX_C PF14601.1 CBK20069.2 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Histone PF00125.19 CBK20070.2 - 7.5e-21 74.0 0.2 1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20070.2 - 2.6e-05 24.2 0.2 5.3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADH_N PF08240.7 CBK20071.2 - 3.5e-11 42.8 0.3 1e-10 41.3 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CBK20071.2 - 8.6e-11 42.8 0.0 2.5e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CBK20071.2 - 9.6e-10 38.1 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CBK20071.2 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DNA_processg_A PF02481.10 CBK20071.2 - 0.16 10.8 0.3 0.26 10.1 0.2 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Glyco_hydro_18 PF00704.23 CBK20072.2 - 7.8e-97 324.7 3.6 9.9e-97 324.4 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3149 PF11346.3 CBK20072.2 - 0.24 11.0 1.6 0.5 9.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Tubulin PF00091.20 CBK20073.2 - 1.7e-71 240.4 0.1 2.6e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK20073.2 - 1.9e-43 147.4 0.1 3.2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBK20073.2 - 7.6e-08 32.4 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBK20073.2 - 0.035 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain MFS_1 PF07690.11 CBK20074.2 - 1.5e-20 73.2 64.1 7.3e-18 64.3 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nitroreductase PF00881.19 CBK20075.2 - 2e-27 96.0 0.0 2.6e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.19 CBK20076.2 - 9.7e-07 28.7 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Proteasome PF00227.21 CBK20077.2 - 1e-54 184.6 0.6 1.5e-54 184.1 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK20077.2 - 3.7e-11 42.1 0.1 6.8e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1206 PF06724.6 CBK20077.2 - 0.011 15.4 0.5 0.048 13.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) ABC2_membrane_2 PF12679.2 CBK20077.2 - 0.11 11.2 8.9 0.46 9.2 4.6 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein CopD PF05425.8 CBK20077.2 - 0.82 9.9 13.7 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Copper resistance protein D DUF3551 PF12071.3 CBK20077.2 - 1.6 8.3 7.9 5.7 6.5 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) DUF805 PF05656.9 CBK20077.2 - 1.7 8.4 9.2 0.45 10.3 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF983 PF06170.7 CBK20077.2 - 9 6.4 19.3 2.9 8.0 9.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Ribosomal_L38e PF01781.13 CBK20079.2 - 5.2e-30 103.0 4.1 7.6e-30 102.4 2.9 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Laminin_II PF06009.7 CBK20079.2 - 0.043 13.5 1.2 0.063 13.0 0.3 1.6 1 1 1 2 2 2 0 Laminin Domain II WavE PF07507.6 CBK20079.2 - 0.067 12.0 0.4 0.41 9.4 0.0 1.9 1 1 1 2 2 2 0 WavE lipopolysaccharide synthesis DHO_dh PF01180.16 CBK20080.2 - 1e-49 169.0 0.0 1.3e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase SURF2 PF05477.6 CBK20081.2 - 5.2e-25 87.9 1.5 6e-25 87.7 1.1 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF2870 PF11069.3 CBK20081.2 - 0.029 14.4 1.4 0.071 13.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) PHO4 PF01384.15 CBK20082.2 - 1.9e-112 375.1 26.9 3.3e-112 374.3 18.6 1.4 1 0 0 1 1 1 1 Phosphate transporter family DUF2048 PF09752.4 CBK20082.2 - 1.5e-70 237.7 0.0 2.4e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CBK20082.2 - 2e-07 31.1 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBK20082.2 - 1.6e-06 27.9 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family He_PIG PF05345.7 CBK20083.2 - 5.7e-18 64.6 38.0 1.9e-05 24.5 1.5 6.5 5 0 0 5 5 5 5 Putative Ig domain PA14 PF07691.7 CBK20083.2 - 3.6e-16 59.1 1.4 6.5e-10 38.8 0.0 3.4 3 0 0 3 3 3 2 PA14 domain F5_F8_type_C PF00754.20 CBK20083.2 - 0.0013 18.5 3.1 0.0013 18.5 2.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain TMEM154 PF15102.1 CBK20083.2 - 0.22 11.2 0.3 0.52 9.9 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family PCI PF01399.22 CBK20085.2 - 0.0069 16.6 2.3 0.0079 16.4 0.1 2.2 2 1 0 2 2 2 1 PCI domain Cyclin_N PF00134.18 CBK20086.2 - 0.00023 20.7 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CBK20086.2 - 0.026 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin Adenylsucc_synt PF00709.16 CBK20087.2 - 3.9e-158 526.5 0.0 4.5e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Pkinase PF00069.20 CBK20089.2 - 4.5e-74 248.8 0.0 5.9e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20089.2 - 4.3e-39 134.1 0.0 6.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.19 CBK20089.2 - 4.7e-10 39.2 0.1 1.7e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.1 CBK20089.2 - 2.7e-06 26.5 0.0 2.2e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBK20089.2 - 0.04 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.1 CBK20090.2 - 0.084 12.6 0.0 0.38 10.5 0.0 2.1 1 1 1 2 2 2 0 Leucine rich repeat PrmA PF06325.8 CBK20091.2 - 1.4e-10 40.7 0.0 2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CBK20091.2 - 2.9e-08 33.4 0.0 5.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK20091.2 - 3.7e-08 33.9 0.0 6.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK20091.2 - 9.8e-08 32.0 0.4 2e-07 31.0 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK20091.2 - 1.4e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBK20091.2 - 0.00065 20.1 0.0 0.0019 18.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain DOT1 PF08123.8 CBK20091.2 - 0.00066 19.0 0.0 0.00094 18.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 CBK20091.2 - 0.0015 17.5 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CBK20091.2 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBK20091.2 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 CBK20091.2 - 0.0055 16.2 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 CBK20091.2 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBK20091.2 - 0.012 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PRMT5 PF05185.11 CBK20091.2 - 0.014 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 CBK20091.2 - 0.024 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 CBK20091.2 - 0.037 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 CBK20091.2 - 0.044 14.1 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CBK20091.2 - 0.05 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Homeobox_KN PF05920.6 CBK20092.2 - 1.4e-12 47.0 0.5 2.8e-12 46.1 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBK20092.2 - 1.7e-08 33.9 0.1 4.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Proteasome PF00227.21 CBK20093.2 - 1e-32 112.9 0.0 1.2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK20093.2 - 8.4e-13 47.3 1.0 3.6e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Shufflon_N PF04917.7 CBK20093.2 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Radical_SAM PF04055.16 CBK20094.2 - 5.4e-14 52.6 0.1 9.3e-13 48.6 0.1 2.4 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CBK20094.2 - 2.9e-11 43.2 0.1 9.5e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBK20094.2 - 0.024 14.7 0.7 0.93 9.7 0.4 2.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK20094.2 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Corona_nucleoca PF00937.13 CBK20095.2 - 0.016 14.1 13.7 0.022 13.7 9.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MDFI PF15316.1 CBK20095.2 - 1.7 8.6 7.2 3.4 7.6 5.0 1.5 1 0 0 1 1 1 0 MyoD family inhibitor Hid1 PF12722.2 CBK20095.2 - 3.3 5.2 15.7 3.6 5.1 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CBK20095.2 - 7.2 4.9 6.4 7.8 4.7 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.27 CBK20096.2 - 4.5e-27 92.8 23.4 3.9e-06 26.5 0.3 9.1 8 1 1 9 9 9 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBK20096.2 - 3.9e-05 22.5 0.3 0.014 14.1 0.1 3.5 3 1 1 4 4 4 1 Nup133 N terminal like PDZ PF00595.19 CBK20096.2 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBK20096.2 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.27 CBK20097.2 - 1.2e-22 78.8 0.4 5e-06 26.1 0.5 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBK20097.2 - 0.012 14.3 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 CBK20097.2 - 0.029 12.5 0.3 1.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RNase_T PF00929.19 CBK20098.2 - 2.2e-24 86.6 0.0 3.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Maf PF02545.9 CBK20098.2 - 1.7e-15 56.6 0.1 3.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Maf-like protein TFIIF_alpha PF05793.7 CBK20098.2 - 0.12 10.6 14.4 0.16 10.3 10.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L31e PF01198.14 CBK20099.2 - 4e-30 103.2 0.2 4.9e-30 103.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e VPS9 PF02204.13 CBK20100.2 - 1.2e-28 99.1 0.0 1.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DEAD PF00270.24 CBK20101.2 - 9.4e-41 139.1 0.0 1.7e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK20101.2 - 7.9e-23 80.1 0.1 1.7e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 CBK20101.2 - 1.4e-20 73.0 0.0 3.9e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain CMS1 PF14617.1 CBK20101.2 - 0.095 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Gp-FAR-1 PF05823.7 CBK20101.2 - 0.13 12.1 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ResIII PF04851.10 CBK20101.2 - 0.17 11.7 0.0 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 CBK20102.2 - 1.2e-58 194.5 6.8 3.8e-14 52.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20102.2 - 1.2e-45 153.3 1.2 1.2e-09 37.9 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20102.2 - 3.8e-27 93.8 3.4 3.1e-06 26.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBK20102.2 - 2.3e-16 59.2 0.0 7.1e-16 57.6 0.0 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CBK20102.2 - 3.8e-08 33.1 9.3 0.0068 16.2 0.2 4.4 3 1 1 4 4 4 3 RNA binding motif DUF4651 PF15513.1 CBK20102.2 - 0.00079 18.8 1.4 0.65 9.4 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4651) Nup35_RRM_2 PF14605.1 CBK20102.2 - 0.0078 15.9 0.6 15 5.4 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Ribosomal_L37 PF08561.5 CBK20103.2 - 0.51 9.9 2.4 0.6 9.7 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF3886 PF13025.1 CBK20103.2 - 0.57 10.1 11.5 0.75 9.8 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) LRR_8 PF13855.1 CBK20104.2 - 3.8e-06 26.5 0.1 0.029 14.1 0.0 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK20104.2 - 5.7e-06 25.8 1.2 0.057 13.0 0.1 4.2 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) RNA_pol_Rpb4 PF03874.11 CBK20106.2 - 1e-09 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Na_Ca_ex PF01699.19 CBK20107.2 - 5.9e-20 71.3 9.6 5.9e-20 71.3 6.7 2.6 2 1 1 3 3 3 1 Sodium/calcium exchanger protein YfhO PF09586.5 CBK20107.2 - 0.0033 15.5 0.7 0.0033 15.5 0.5 2.3 2 1 1 3 3 3 1 Bacterial membrane protein YfhO FixQ PF05545.6 CBK20107.2 - 6.4 6.4 6.7 3.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ SMC_N PF02463.14 CBK20108.2 - 9.9e-19 67.4 11.2 1.7e-18 66.7 7.7 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK20108.2 - 4.3e-06 26.9 1.8 8.7e-06 25.9 1.2 1.8 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CBK20108.2 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cas_APE2256 PF09651.5 CBK20108.2 - 0.017 14.8 0.0 0.072 12.7 0.0 2.2 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) SR-25 PF10500.4 CBK20108.2 - 0.049 13.1 10.8 0.029 13.8 6.2 1.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF885 PF05960.6 CBK20108.2 - 0.27 10.3 9.7 0.43 9.6 6.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CCDC92 PF14916.1 CBK20108.2 - 0.31 10.6 10.1 0.4 10.2 0.8 2.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ABC_tran PF00005.22 CBK20108.2 - 0.64 10.3 9.9 22 5.3 6.8 2.7 1 1 0 1 1 1 0 ABC transporter Allexi_40kDa PF05549.6 CBK20108.2 - 1.8 7.8 13.1 2.1 7.5 1.8 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.17 CBK20108.2 - 2.1 8.4 27.3 2.2 8.3 7.6 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 CBK20108.2 - 3.5 7.9 20.1 1.7 9.0 4.0 3.4 3 0 0 3 3 3 0 Snapin/Pallidin ABC_tran_2 PF12848.2 CBK20108.2 - 3.9 7.3 16.8 0.15 11.8 0.2 3.3 3 0 0 3 3 3 0 ABC transporter DUF4407 PF14362.1 CBK20108.2 - 7 5.5 24.4 3.1 6.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Striatin PF08232.7 CBK20108.2 - 8.9 6.6 20.8 4.2 7.6 4.1 2.3 2 0 0 2 2 2 0 Striatin family SMC_N PF02463.14 CBK20109.2 - 8.7e-20 70.8 0.2 8.7e-20 70.8 0.1 1.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBK20109.2 - 6.2e-16 59.3 16.3 6.2e-16 59.3 11.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 CBK20109.2 - 2.4e-08 33.3 0.0 6.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBK20109.2 - 2e-06 27.9 0.3 3.8e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBK20109.2 - 4.8e-06 25.8 8.7 3.4e-05 23.0 6.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 CBK20109.2 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.1 CBK20109.2 - 0.0014 17.1 12.5 0.014 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CBK20109.2 - 0.005 17.1 4.5 0.012 15.9 0.0 2.8 2 1 0 2 2 2 1 ABC transporter Reo_sigmaC PF04582.7 CBK20109.2 - 0.052 12.7 0.3 0.087 11.9 0.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Miro PF08477.8 CBK20109.2 - 0.14 12.7 0.4 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 CBK20109.2 - 0.23 12.2 0.8 3 8.6 0.6 2.8 1 1 0 1 1 1 0 AAA domain DUF745 PF05335.8 CBK20109.2 - 0.68 9.4 3.3 1.1 8.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) WXG100 PF06013.7 CBK20109.2 - 6 6.9 8.8 2.8 8.0 1.4 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Fer2_3 PF13085.1 CBK20110.2 - 7.8e-33 112.5 0.1 1.4e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK20110.2 - 9.6e-10 38.6 6.9 9.6e-10 38.6 4.8 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK20110.2 - 1.3e-09 37.9 4.9 1.3e-09 37.9 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK20110.2 - 4.3e-06 27.0 3.0 4.3e-06 27.0 2.1 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK20110.2 - 0.0002 21.0 3.5 0.0002 21.0 2.4 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CBK20110.2 - 0.0003 20.4 0.4 0.0003 20.4 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CBK20110.2 - 0.0006 20.0 10.7 0.048 13.9 0.2 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK20110.2 - 0.002 18.4 5.2 0.002 18.4 3.6 2.9 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK20110.2 - 1.2 9.1 16.3 1.3 9.0 2.8 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.1 CBK20110.2 - 3.3 8.3 8.7 2.3 8.8 0.2 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain Sec6 PF06046.8 CBK20111.2 - 2.9e-07 28.9 0.4 5.6e-07 28.0 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 AAA_13 PF13166.1 CBK20111.2 - 0.0042 15.6 3.3 0.0055 15.2 2.3 1.1 1 0 0 1 1 1 1 AAA domain Frigida PF07899.6 CBK20111.2 - 0.013 14.3 2.0 1.3 7.7 0.6 2.1 2 0 0 2 2 2 0 Frigida-like protein IncA PF04156.9 CBK20111.2 - 0.016 14.7 4.2 0.031 13.8 2.9 1.5 1 1 0 1 1 1 0 IncA protein Sec8_exocyst PF04048.9 CBK20111.2 - 0.022 14.4 5.2 0.07 12.7 3.0 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.7 CBK20111.2 - 0.13 12.5 6.6 2.5 8.4 2.2 3.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein HrpJ PF07201.6 CBK20111.2 - 0.2 11.6 3.4 1 9.3 0.1 2.4 2 0 0 2 2 2 0 HrpJ-like domain COG2 PF06148.6 CBK20111.2 - 0.21 11.4 4.5 0.45 10.3 2.4 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.8 CBK20111.2 - 0.26 11.5 5.5 0.44 10.8 0.4 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Baculo_PEP_C PF04513.7 CBK20111.2 - 0.44 10.3 6.9 0.97 9.2 4.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.1 CBK20111.2 - 1.7 9.0 5.4 3.2 8.2 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Ribosomal_S3Ae PF01015.13 CBK20112.2 - 1.7e-74 249.3 4.0 2.2e-74 249.0 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.17 CBK20112.2 - 0.0025 17.5 0.1 0.0025 17.5 0.1 2.0 3 0 0 3 3 3 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.11 CBK20112.2 - 0.04 13.2 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF1875 PF08961.5 CBK20113.2 - 0.027 13.7 2.7 0.037 13.3 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Phage_Nu1 PF07471.7 CBK20113.2 - 0.03 13.7 3.2 0.038 13.4 1.3 1.8 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 DUF106 PF01956.11 CBK20113.2 - 0.14 11.6 5.4 0.25 10.8 3.7 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF4407 PF14362.1 CBK20113.2 - 0.22 10.4 3.6 0.3 10.0 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spectrin PF00435.16 CBK20113.2 - 0.38 11.0 9.3 3.8 7.8 2.5 2.7 2 1 0 2 2 2 0 Spectrin repeat FlgM PF04316.8 CBK20113.2 - 0.76 9.7 4.9 8.9 6.3 0.0 3.1 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM OEP PF02321.13 CBK20113.2 - 1.1 8.7 9.8 2.3 7.7 6.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4140 PF13600.1 CBK20113.2 - 2 8.9 8.1 1.8 9.0 2.3 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3829 PF12889.2 CBK20113.2 - 2 7.5 17.0 3.5 6.7 11.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2407_C PF13373.1 CBK20113.2 - 9.7 6.1 9.4 3.3 7.6 2.7 2.4 2 1 1 3 3 3 0 DUF2407 C-terminal domain SNARE PF05739.14 CBK20114.2 - 1.4e-08 34.3 5.7 3.7e-08 32.9 3.9 1.7 1 1 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 CBK20114.2 - 0.00047 19.6 1.9 0.00047 19.6 1.3 1.4 1 1 1 2 2 2 1 Synaptobrevin T2SF PF00482.18 CBK20114.2 - 0.0028 17.5 0.1 0.0033 17.3 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Cauli_AT PF03233.8 CBK20114.2 - 0.0072 16.0 1.6 0.0085 15.8 1.1 1.1 1 0 0 1 1 1 1 Aphid transmission protein Rifin_STEVOR PF02009.11 CBK20114.2 - 0.0097 15.5 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 CBK20114.2 - 0.013 15.4 1.3 0.017 15.1 0.9 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FliJ PF02050.11 CBK20114.2 - 0.017 15.1 8.0 0.02 14.9 5.6 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein AAA_27 PF13514.1 CBK20114.2 - 0.034 11.8 3.6 0.036 11.7 2.5 1.0 1 0 0 1 1 1 0 AAA domain Peptidase_C65 PF10275.4 CBK20114.2 - 0.037 13.3 1.5 0.041 13.2 1.0 1.0 1 0 0 1 1 1 0 Peptidase C65 Otubain Lebercilin PF15619.1 CBK20114.2 - 0.039 13.3 11.6 0.05 13.0 8.0 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_UL25 PF01499.11 CBK20114.2 - 0.05 11.9 5.8 0.056 11.7 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2959 PF11172.3 CBK20114.2 - 0.053 13.2 1.4 0.065 12.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF1664 PF07889.7 CBK20114.2 - 0.065 13.0 3.7 0.054 13.2 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Acyl-CoA_dh_C PF12806.2 CBK20114.2 - 0.084 12.7 1.2 4 7.2 0.2 2.0 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like CALCOCO1 PF07888.6 CBK20114.2 - 0.088 11.0 4.3 0.1 10.8 3.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like PEP-utilisers_N PF05524.8 CBK20114.2 - 0.099 12.4 3.3 0.48 10.2 0.4 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal HXXSHH PF07586.6 CBK20114.2 - 0.1 11.5 1.3 0.11 11.3 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4404 PF14357.1 CBK20114.2 - 0.11 12.9 5.6 0.16 12.4 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Serine_rich PF08824.5 CBK20114.2 - 0.12 12.1 2.4 0.17 11.5 1.4 1.4 1 1 0 1 1 1 0 Serine rich protein interaction domain ALIX_LYPXL_bnd PF13949.1 CBK20114.2 - 0.12 11.2 5.5 0.14 11.0 3.8 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TMP_2 PF06791.8 CBK20114.2 - 0.15 11.6 0.4 0.16 11.5 0.3 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Syntaxin PF00804.20 CBK20114.2 - 0.2 11.8 8.1 0.27 11.4 5.6 1.1 1 0 0 1 1 1 0 Syntaxin FixQ PF05545.6 CBK20114.2 - 0.27 10.9 2.0 0.4 10.3 1.4 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RmuC PF02646.11 CBK20114.2 - 0.29 9.9 7.1 0.33 9.7 4.9 1.1 1 0 0 1 1 1 0 RmuC family DUF4559 PF15112.1 CBK20114.2 - 0.31 10.1 4.6 0.34 10.0 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) PilJ PF13675.1 CBK20114.2 - 0.36 11.1 2.4 0.48 10.7 1.7 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2312 PF10073.4 CBK20114.2 - 0.4 10.0 4.9 0.61 9.4 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3435 PF11917.3 CBK20114.2 - 0.42 9.2 4.1 0.48 9.0 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) BMFP PF04380.8 CBK20114.2 - 0.65 10.1 4.8 8.7 6.5 0.4 2.2 1 1 1 2 2 2 0 Membrane fusogenic activity DUF883 PF05957.8 CBK20114.2 - 0.74 10.2 3.1 1.2 9.5 2.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF812 PF05667.6 CBK20114.2 - 1 7.8 8.8 1.1 7.6 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF342 PF03961.8 CBK20114.2 - 1.4 7.2 6.3 1.5 7.1 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 CBK20114.2 - 1.8 8.5 11.9 2.8 7.9 8.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 CBK20114.2 - 2.4 8.2 5.4 4.5 7.4 3.8 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.6 CBK20114.2 - 2.5 7.3 4.9 2.9 7.1 3.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein HSCB_C PF07743.8 CBK20114.2 - 2.6 8.5 6.7 1.3 9.4 1.2 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF848 PF05852.6 CBK20114.2 - 2.6 7.8 7.9 6.9 6.5 5.5 1.6 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) EMP24_GP25L PF01105.19 CBK20114.2 - 3.3 7.3 7.5 27 4.4 5.2 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.7 CBK20114.2 - 3.5 7.9 6.8 41 4.5 4.6 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mnd1 PF03962.10 CBK20114.2 - 3.7 7.1 7.3 4.4 6.9 5.0 1.1 1 0 0 1 1 1 0 Mnd1 family Spc7 PF08317.6 CBK20114.2 - 3.8 6.0 8.0 4.3 5.8 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 CBK20114.2 - 4.8 7.6 9.1 3.1 8.2 1.1 2.2 1 1 1 2 2 2 0 SlyX Laps PF10169.4 CBK20114.2 - 6 7.1 7.6 6.8 6.9 5.3 1.1 1 0 0 1 1 1 0 Learning-associated protein TB2_DP1_HVA22 PF03134.14 CBK20115.2 - 4.6e-05 23.0 5.1 4.6e-05 23.0 3.5 2.3 1 1 1 2 2 2 1 TB2/DP1, HVA22 family YwiC PF14256.1 CBK20115.2 - 0.62 10.1 8.0 1.4 8.9 5.7 1.5 1 1 1 2 2 2 0 YwiC-like protein DUF161 PF02588.10 CBK20115.2 - 9.3 6.6 7.2 0.69 10.2 1.5 1.6 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 PAT1 PF09770.4 CBK20116.2 - 0.00013 20.3 0.3 0.00017 20.0 0.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PNP_UDP_1 PF01048.15 CBK20117.2 - 4.2e-31 107.7 0.1 5e-31 107.4 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily UAA PF08449.6 CBK20119.2 - 1.7e-41 142.1 13.5 2e-41 141.8 9.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBK20119.2 - 9.7e-05 22.0 14.2 0.00064 19.3 9.8 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 CBK20119.2 - 0.00036 20.5 12.6 0.00048 20.1 4.5 2.2 2 0 0 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.10 CBK20119.2 - 0.2 10.7 4.7 0.08 12.0 1.3 1.7 1 1 1 2 2 2 0 Nucleotide-sugar transporter ASFV_J13L PF05568.6 CBK20119.2 - 0.21 11.1 0.4 0.45 10.0 0.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3671 PF12420.3 CBK20119.2 - 0.33 10.9 6.4 3.9 7.4 4.4 2.2 1 1 0 1 1 1 0 Protein of unknown function EmrE PF13536.1 CBK20119.2 - 2.2 8.5 16.9 1.9 8.6 5.1 2.6 3 0 0 3 3 3 0 Multidrug resistance efflux transporter PsbT PF01405.12 CBK20119.2 - 7.2 6.2 6.4 0.76 9.4 0.7 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre T protein bZIP_1 PF00170.16 CBK20120.2 - 2.4e-08 33.8 11.7 4.4e-08 32.9 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBK20120.2 - 2.5e-05 23.9 12.0 4.9e-05 23.0 8.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper GvpL_GvpF PF06386.6 CBK20120.2 - 0.11 12.0 4.0 0.17 11.4 2.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Cortex-I_coil PF09304.5 CBK20120.2 - 0.13 12.3 5.0 0.27 11.3 3.5 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil NAM-associated PF14303.1 CBK20120.2 - 0.15 12.3 6.6 0.23 11.7 4.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Acetyltransf_1 PF00583.19 CBK20121.2 - 1.3e-13 50.8 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBK20121.2 - 1.4e-08 34.3 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBK20121.2 - 3.2e-07 30.4 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBK20121.2 - 2.8e-06 27.3 0.0 3.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBK20121.2 - 4.3e-06 26.7 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBK20121.2 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBK20121.2 - 0.00039 20.5 0.0 0.00051 20.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK20121.2 - 0.0077 16.1 0.0 0.0099 15.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 CBK20121.2 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region V-ATPase_H_C PF11698.3 CBK20122.2 - 4e-33 113.8 5.1 8.8e-32 109.5 0.0 3.2 2 1 1 3 3 3 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 CBK20122.2 - 2.5e-22 79.3 9.7 3.2e-21 75.7 2.0 2.4 2 0 0 2 2 2 2 V-ATPase subunit H Pico_P2B PF01552.12 CBK20122.2 - 0.22 11.6 2.4 6.1 7.0 0.2 2.7 2 0 0 2 2 2 0 Picornavirus 2B protein Arm PF00514.18 CBK20122.2 - 0.6 10.0 3.0 20 5.1 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat AAA PF00004.24 CBK20123.2 - 7.3e-37 126.5 0.0 1.5e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK20123.2 - 1.5e-06 28.4 0.1 0.00021 21.4 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CBK20123.2 - 2.7e-06 28.1 0.3 1.1e-05 26.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK20123.2 - 6.7e-06 26.0 0.0 2.3e-05 24.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBK20123.2 - 1.1e-05 25.4 0.0 0.00056 19.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBK20123.2 - 3.8e-05 23.4 0.3 0.00043 20.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK20123.2 - 3.9e-05 22.8 0.0 8.9e-05 21.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBK20123.2 - 4.4e-05 23.3 0.0 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK20123.2 - 4.4e-05 23.7 0.0 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBK20123.2 - 4.9e-05 22.2 0.1 0.00019 20.2 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 CBK20123.2 - 0.00014 21.0 0.0 0.00033 19.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 CBK20123.2 - 0.00014 21.8 0.0 0.0006 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CBK20123.2 - 0.00049 19.5 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBK20123.2 - 0.00081 18.8 0.2 0.0082 15.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBK20123.2 - 0.00085 18.5 0.1 0.0018 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBK20123.2 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK20123.2 - 0.0015 18.6 0.5 0.019 15.1 0.0 2.8 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.1 CBK20123.2 - 0.0024 17.4 0.2 0.0057 16.2 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBK20123.2 - 0.0032 16.9 0.7 2.4 7.4 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain Sigma54_activ_2 PF14532.1 CBK20123.2 - 0.0034 17.4 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 1 1 Sigma-54 interaction domain DUF815 PF05673.8 CBK20123.2 - 0.0038 16.1 0.1 0.018 13.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CBK20123.2 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CBK20123.2 - 0.0052 16.4 0.6 0.024 14.3 0.0 2.4 3 1 1 4 4 3 1 NACHT domain IPT PF01745.11 CBK20123.2 - 0.006 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase Parvo_NS1 PF01057.12 CBK20123.2 - 0.0093 14.8 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 CPT PF07931.7 CBK20123.2 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 CBK20123.2 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 CBK20123.2 - 0.019 14.8 0.0 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.21 CBK20123.2 - 0.02 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 CBK20123.2 - 0.033 13.7 0.0 0.061 12.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 CBK20123.2 - 0.044 13.4 0.2 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CBK20123.2 - 0.076 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 CBK20123.2 - 0.11 11.9 0.3 3.9 6.8 0.0 3.0 2 1 1 3 3 3 0 Guanylate kinase AAA_21 PF13304.1 CBK20123.2 - 0.21 11.5 1.3 22 4.8 0.0 2.6 2 1 0 3 3 3 0 AAA domain FKBP_C PF00254.23 CBK20124.2 - 2.5e-32 110.7 0.0 1.2e-31 108.6 0.0 2.0 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Enolase_C PF00113.17 CBK20125.2 - 2.3e-119 397.7 0.0 3.1e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBK20125.2 - 3.2e-53 179.1 0.0 5.8e-53 178.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CBK20125.2 - 0.00044 19.2 0.0 0.00071 18.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CBK20125.2 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Enolase C-terminal domain-like Prokineticin PF06607.6 CBK20125.2 - 0.066 13.3 0.5 5.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Prokineticin SUI1 PF01253.17 CBK20126.2 - 2.1e-08 33.8 0.4 4.7e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 IPK PF03770.11 CBK20128.2 - 9e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase DnaJ_CXXCXGXG PF00684.14 CBK20129.2 - 1.4e-05 25.0 21.8 0.0004 20.3 14.9 2.8 1 1 1 2 2 2 2 DnaJ central domain DUF3439 PF11921.3 CBK20129.2 - 2 8.1 8.8 5.9 6.6 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) ABC_tran PF00005.22 CBK20132.2 - 1.9e-73 245.2 0.0 1.3e-37 129.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK20132.2 - 7.6e-49 166.5 16.1 6.7e-26 91.3 1.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CBK20132.2 - 4.7e-17 62.8 0.2 0.0047 16.9 0.0 4.9 3 2 1 4 4 4 3 AAA domain AAA_16 PF13191.1 CBK20132.2 - 2.7e-12 47.0 0.0 5.2e-06 26.5 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CBK20132.2 - 8.6e-12 44.7 0.5 0.00025 20.3 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBK20132.2 - 2.4e-11 43.8 1.8 0.00021 21.4 0.2 4.4 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK20132.2 - 1.1e-09 37.7 0.1 0.00089 18.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK20132.2 - 5.4e-09 35.4 0.2 0.0043 16.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK20132.2 - 7.5e-09 36.4 0.0 0.0076 17.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBK20132.2 - 1.6e-08 34.2 1.8 0.13 11.6 0.0 3.7 3 1 0 3 3 3 3 AAA domain AAA PF00004.24 CBK20132.2 - 2e-08 34.4 0.2 0.0014 18.8 0.0 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 CBK20132.2 - 4.9e-08 31.9 1.5 0.0006 18.5 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CBK20132.2 - 2.1e-07 30.7 3.4 0.0028 17.5 0.5 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CBK20132.2 - 3.1e-07 30.7 0.4 0.01 16.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 CBK20132.2 - 4.8e-07 29.5 2.0 0.11 11.9 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain AAA_30 PF13604.1 CBK20132.2 - 2.9e-06 26.9 0.8 0.41 10.1 0.1 4.6 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.9 CBK20132.2 - 1.4e-05 24.7 0.6 1.4 8.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CBK20132.2 - 5.5e-05 22.0 7.1 0.054 12.1 0.0 3.1 3 0 0 3 3 2 2 G-protein alpha subunit MobB PF03205.9 CBK20132.2 - 9.1e-05 22.1 0.2 0.67 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBK20132.2 - 0.00014 22.2 8.9 0.018 15.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CBK20132.2 - 0.00014 21.7 0.1 0.51 10.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase NB-ARC PF00931.17 CBK20132.2 - 0.00028 19.8 0.1 0.16 10.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 CBK20132.2 - 0.00035 20.4 0.2 0.48 10.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBK20132.2 - 0.00036 20.6 0.0 1.2 9.3 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 CBK20132.2 - 0.00046 19.8 0.8 1.2 8.9 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain ArgK PF03308.11 CBK20132.2 - 0.001 17.9 0.0 0.29 9.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein IstB_IS21 PF01695.12 CBK20132.2 - 0.0011 18.4 0.1 6.2 6.1 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBK20132.2 - 0.0019 17.3 0.0 0.6 9.1 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin Rad17 PF03215.10 CBK20132.2 - 0.002 16.8 0.0 0.14 10.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PRK PF00485.13 CBK20132.2 - 0.0024 17.4 2.4 0.72 9.3 0.0 2.9 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.21 CBK20132.2 - 0.0026 17.2 0.0 4.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Miro PF08477.8 CBK20132.2 - 0.0028 18.1 0.1 0.61 10.5 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CBK20132.2 - 0.0038 16.7 0.0 0.082 12.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family PhoH PF02562.11 CBK20132.2 - 0.0045 16.2 0.1 4.2 6.5 0.0 3.5 3 0 0 3 3 3 0 PhoH-like protein AAA_14 PF13173.1 CBK20132.2 - 0.0052 16.6 0.0 5.9 6.8 0.0 3.3 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.12 CBK20132.2 - 0.006 16.1 0.5 0.52 9.7 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Sigma54_activ_2 PF14532.1 CBK20132.2 - 0.009 16.0 0.0 7.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBK20132.2 - 0.0099 15.0 0.0 0.8 8.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBK20132.2 - 0.013 15.2 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 CBK20132.2 - 0.013 14.5 4.9 0.14 11.1 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain T2SE PF00437.15 CBK20132.2 - 0.016 14.1 0.1 0.14 11.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 CBK20132.2 - 0.021 13.8 0.1 0.24 10.3 0.0 2.5 3 0 0 3 3 2 0 KAP family P-loop domain DUF815 PF05673.8 CBK20132.2 - 0.025 13.5 0.0 1.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 CBK20132.2 - 0.028 14.1 0.9 11 5.6 0.0 3.1 4 0 0 4 4 2 0 NTPase DUF87 PF01935.12 CBK20132.2 - 0.028 14.2 5.7 0.22 11.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 CBK20132.2 - 0.035 13.6 0.2 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 CBK20132.2 - 0.072 12.7 0.1 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MoeA_C PF03454.10 CBK20132.2 - 0.11 12.4 0.0 7.9 6.5 0.0 3.2 3 0 0 3 3 2 0 MoeA C-terminal region (domain IV) AAA_28 PF13521.1 CBK20132.2 - 0.13 12.2 0.7 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AcetylCoA_hyd_C PF13336.1 CBK20133.2 - 1.8e-41 141.4 0.0 2.7e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 CBK20133.2 - 8.9e-37 126.7 0.0 2.4e-36 125.3 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.18 CBK20133.2 - 0.053 12.6 0.1 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Coenzyme A transferase Ribosomal_L19e PF01280.15 CBK20134.2 - 2.1e-56 189.8 11.7 2.7e-56 189.4 8.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Arm PF00514.18 CBK20135.2 - 6.1e-41 136.8 10.1 1.3e-12 46.9 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBK20135.2 - 2.5e-08 34.0 0.0 8.8e-05 22.7 0.0 3.8 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 CBK20135.2 - 4.2e-08 33.4 0.1 1.8e-05 25.0 0.0 4.3 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 CBK20135.2 - 2e-05 24.2 0.0 0.0091 16.0 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Atx10homo_assoc PF09759.4 CBK20135.2 - 0.0031 17.1 1.5 0.1 12.3 0.0 3.6 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.8 CBK20135.2 - 0.0047 16.0 0.6 3.4 6.6 0.0 3.2 2 1 2 4 4 4 1 Armadillo-like Peptidase_A22B PF04258.8 CBK20136.2 - 9.9e-64 215.6 14.7 1.1e-63 215.4 10.2 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CBK20136.2 - 5.9e-05 22.3 14.4 0.00012 21.3 6.5 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1119) VIT1 PF01988.14 CBK20136.2 - 0.16 11.4 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 VIT family MgtE PF01769.11 CBK20136.2 - 2 8.7 6.2 1.9 8.8 0.2 2.6 2 0 0 2 2 2 0 Divalent cation transporter UPF0016 PF01169.14 CBK20137.2 - 4e-35 119.7 24.3 4.7e-21 74.6 4.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 IF4E PF01652.13 CBK20138.2 - 4.2e-42 143.4 0.2 5.2e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA PF00004.24 CBK20139.2 - 1e-39 135.7 0.0 1.9e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK20139.2 - 2e-06 27.9 0.0 5.7e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBK20139.2 - 3.9e-06 26.6 0.0 2.2e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK20139.2 - 4.6e-05 22.5 0.0 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK20139.2 - 0.00017 21.7 0.0 0.088 12.9 0.0 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 CBK20139.2 - 0.00018 20.3 0.0 0.00034 19.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CBK20139.2 - 0.00061 19.7 0.0 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBK20139.2 - 0.002 18.9 0.0 0.0047 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK20139.2 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK20139.2 - 0.0046 17.1 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CBK20139.2 - 0.012 15.0 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 CBK20139.2 - 0.02 14.2 0.6 0.27 10.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain Vps4_C PF09336.5 CBK20139.2 - 0.022 14.6 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain NACHT PF05729.7 CBK20139.2 - 0.056 13.0 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CBK20139.2 - 0.077 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CBK20139.2 - 0.078 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBK20139.2 - 0.082 11.5 0.0 0.22 10.1 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 CBK20139.2 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CBK20139.2 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBK20139.2 - 0.11 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CBK20139.2 - 0.11 11.6 0.1 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SNARE PF05739.14 CBK20140.2 - 1.3e-11 43.9 6.9 1.3e-11 43.9 4.8 3.4 4 1 1 5 5 4 1 SNARE domain V_ATPase_I PF01496.14 CBK20140.2 - 0.0053 14.6 1.2 0.0053 14.6 0.8 2.1 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family UPF0184 PF03670.8 CBK20140.2 - 0.0097 16.0 0.9 0.0097 16.0 0.6 3.5 2 2 2 4 4 4 1 Uncharacterised protein family (UPF0184) Reo_sigmaC PF04582.7 CBK20140.2 - 0.011 14.9 0.6 0.055 12.6 0.0 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 CBK20140.2 - 0.016 15.2 1.5 0.016 15.2 1.0 3.1 2 1 1 3 3 3 0 DivIVA protein TMPIT PF07851.8 CBK20140.2 - 0.031 13.3 0.6 0.031 13.3 0.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein SlyX PF04102.7 CBK20140.2 - 0.057 13.7 1.8 0.057 13.7 1.3 3.8 2 2 1 4 4 4 0 SlyX AAA_13 PF13166.1 CBK20140.2 - 0.094 11.1 15.1 0.34 9.2 0.4 2.0 2 0 0 2 2 2 0 AAA domain Eno-Rase_FAD_bd PF07055.7 CBK20140.2 - 0.099 12.6 4.0 0.65 9.9 0.3 3.3 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain ATG16 PF08614.6 CBK20140.2 - 0.12 12.2 14.9 0.92 9.3 1.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FimP PF09766.4 CBK20140.2 - 0.19 10.7 8.3 0.24 10.4 0.1 2.4 2 1 0 2 2 2 0 Fms-interacting protein DUF2400 PF09674.5 CBK20140.2 - 0.37 10.4 8.8 0.33 10.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) DASH_Duo1 PF08651.5 CBK20140.2 - 0.4 10.3 11.7 0.13 11.8 0.6 4.0 3 2 1 4 4 4 0 DASH complex subunit Duo1 HeLo PF14479.1 CBK20140.2 - 0.45 10.2 12.8 4.9 6.8 4.2 2.8 2 1 0 2 2 2 0 Prion-inhibition and propagation Mnd1 PF03962.10 CBK20140.2 - 0.49 10.0 18.7 0.54 9.8 0.5 2.9 2 1 1 3 3 3 0 Mnd1 family Laminin_II PF06009.7 CBK20140.2 - 0.54 10.0 15.9 0.052 13.3 2.3 2.9 2 1 0 2 2 2 0 Laminin Domain II COG5 PF10392.4 CBK20140.2 - 0.57 10.1 6.9 1.5 8.8 0.3 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 KMP11 PF03037.11 CBK20140.2 - 0.61 10.7 9.3 1.1 9.9 0.7 2.8 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 NPV_P10 PF05531.7 CBK20140.2 - 0.71 10.1 13.1 0.33 11.2 2.2 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 CBK20140.2 - 1.1 9.2 14.5 0.2 11.5 4.1 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Bacillus_HBL PF05791.6 CBK20140.2 - 1.6 8.0 16.2 1.4 8.2 3.0 2.7 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YjcZ PF13990.1 CBK20140.2 - 2.2 7.3 5.6 2.1 7.4 0.2 2.2 2 0 0 2 2 2 0 YjcZ-like protein ALIX_LYPXL_bnd PF13949.1 CBK20140.2 - 2.9 6.7 18.2 3.4 6.5 2.2 2.8 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4337 PF14235.1 CBK20140.2 - 3 7.6 12.5 16 5.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) Atg14 PF10186.4 CBK20140.2 - 3.3 6.5 18.9 0.73 8.7 1.7 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF883 PF05957.8 CBK20140.2 - 4.4 7.7 14.0 2.1 8.7 0.8 3.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Ran-binding PF05508.6 CBK20140.2 - 5.5 5.7 12.6 0.065 12.1 1.0 2.2 2 0 0 2 2 2 0 RanGTP-binding protein NESP55 PF06390.7 CBK20141.2 - 0.0075 15.6 8.7 0.008 15.5 6.0 1.2 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) SURF6 PF04935.7 CBK20141.2 - 0.17 11.1 5.3 0.21 10.8 3.7 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Nop14 PF04147.7 CBK20141.2 - 1.5 6.6 11.5 1.8 6.4 7.9 1.0 1 0 0 1 1 1 0 Nop14-like family FNIP_N PF14636.1 CBK20141.2 - 2.8 8.4 8.3 3.7 8.0 5.7 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF2413 PF10310.4 CBK20141.2 - 4.9 5.8 10.4 5.1 5.8 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Peptidase_S64 PF08192.6 CBK20141.2 - 5.1 5.3 7.6 5.8 5.1 5.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Trypan_PARP PF05887.6 CBK20141.2 - 6.7 6.5 16.6 9.6 6.0 11.5 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 CBK20141.2 - 7.3 5.8 9.6 9.1 5.5 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CBK20141.2 - 7.4 4.1 10.3 8.6 3.8 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.6 CBK20142.2 - 1.3e-61 208.4 6.9 3.2e-49 167.5 2.2 2.0 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.27 CBK20143.2 - 6.7e-23 79.6 7.4 7.8e-09 35.0 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Collagen PF01391.13 CBK20143.2 - 1.5e-06 27.6 9.0 2.5e-06 26.9 6.2 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Urm1 PF09138.6 CBK20144.2 - 6.7e-24 83.8 0.3 6.9e-24 83.7 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CBK20144.2 - 2e-05 24.8 0.1 2.5e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 ThiS family TrkA_C PF02080.16 CBK20144.2 - 0.1 12.1 0.1 0.28 10.7 0.1 1.8 1 1 1 2 2 2 0 TrkA-C domain RRP14 PF15459.1 CBK20145.2 - 1.5e-18 66.6 2.0 1.5e-18 66.6 1.4 2.7 3 0 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 DUF2591 PF10765.4 CBK20145.2 - 0.096 12.9 0.5 0.096 12.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) Aldedh PF00171.17 CBK20145.2 - 0.56 8.4 3.9 0.61 8.3 2.7 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Vps39_2 PF10367.4 CBK20145.2 - 2.4 8.3 5.1 15 5.8 1.2 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rep-A_N PF04057.7 CBK20146.2 - 6.9e-10 38.6 0.3 1.1e-09 38.0 0.2 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 CBK20146.2 - 2.2e-06 27.4 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TFIIA PF03153.8 CBK20146.2 - 5 6.9 24.3 6.7 6.4 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CBK20146.2 - 9 4.3 47.8 11 4.0 33.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rep_fac-A_C PF08646.5 CBK20147.2 - 1.1e-36 125.7 0.5 1.3e-36 125.5 0.4 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ribosomal_L7Ae PF01248.21 CBK20148.2 - 3.8e-21 74.3 0.6 6.6e-21 73.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family He_PIG PF05345.7 CBK20149.2 - 2.4e-06 27.4 5.9 0.0026 17.7 0.2 3.1 3 0 0 3 3 3 2 Putative Ig domain He_PIG PF05345.7 CBK20150.2 - 0.00091 19.2 0.2 0.0034 17.3 0.1 2.0 1 0 0 1 1 1 1 Putative Ig domain Shisa PF13908.1 CBK20150.2 - 0.0026 17.9 0.6 0.0049 17.0 0.4 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBK20150.2 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 CBK20150.2 - 0.064 13.6 1.0 0.13 12.6 0.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 CBK20150.2 - 0.16 12.2 1.4 0.35 11.0 1.0 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Myc_target_1 PF15179.1 CBK20150.2 - 0.16 11.5 1.0 9.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Myc target protein 1 Sushi PF00084.15 CBK20150.2 - 0.23 11.8 0.2 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Sushi domain (SCR repeat) Synaptobrevin PF00957.16 CBK20150.2 - 0.42 10.2 8.6 0.88 9.2 6.0 1.5 1 0 0 1 1 1 0 Synaptobrevin DEAD PF00270.24 CBK20151.2 - 3.2e-38 130.8 0.3 5.1e-38 130.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK20151.2 - 2.4e-19 68.9 0.3 6.7e-12 45.1 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBK20151.2 - 2.2e-08 34.1 0.0 2.2e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Astro_capsid PF03115.9 CBK20151.2 - 0.16 10.1 2.5 0.28 9.4 1.7 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CBK20151.2 - 0.5 8.2 13.7 0.89 7.3 9.5 1.3 1 0 0 1 1 1 0 Nop14-like family mRNA_triPase PF02940.10 CBK20152.2 - 1.4e-11 44.5 1.8 2.9e-11 43.5 1.3 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain SynMuv_product PF06047.6 CBK20152.2 - 0.028 14.1 0.1 0.072 12.8 0.0 1.7 1 1 0 1 1 1 0 Ras-induced vulval development antagonist Ribosomal_L3 PF00297.17 CBK20153.2 - 5.2e-40 137.4 3.6 1.9e-38 132.3 2.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 KOW PF00467.24 CBK20153.2 - 0.46 10.2 3.6 3 7.7 0.1 3.5 3 0 0 3 3 3 0 KOW motif MTS PF05175.9 CBK20154.2 - 0.00036 19.9 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBK20154.2 - 0.00048 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBK20154.2 - 0.0056 15.7 0.0 0.0068 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 CBK20154.2 - 0.022 15.1 0.0 0.051 13.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.7 CBK20154.2 - 0.038 13.2 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase WD40 PF00400.27 CBK20155.2 - 1.1e-12 47.2 2.5 9.2e-06 25.3 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Sec16_C PF12931.2 CBK20155.2 - 5.5e-07 29.6 0.1 1.2e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DUF512 PF04459.7 CBK20155.2 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Fe-S_biosyn PF01521.15 CBK20156.2 - 2.2e-12 46.9 0.0 2.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3753 PF12575.3 CBK20157.2 - 0.044 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) WD40 PF00400.27 CBK20158.2 - 1.1e-09 37.8 0.3 0.00027 20.6 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat LisH PF08513.6 CBK20158.2 - 0.069 12.9 0.1 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 LisH DASH_Dad2 PF08654.5 CBK20159.2 - 1.6e-07 31.2 0.3 1.6e-07 31.2 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DHC_N2 PF08393.8 CBK20159.2 - 0.006 15.1 0.0 0.0069 14.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DASH_Duo1 PF08651.5 CBK20159.2 - 0.069 12.7 0.1 0.087 12.4 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 Histone PF00125.19 CBK20160.2 - 7.5e-21 74.0 0.2 1e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20160.2 - 2.6e-05 24.2 0.2 5.3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK20161.2 - 1.4e-23 82.7 0.1 1.8e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20161.2 - 1.8e-05 24.6 0.0 2.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFX_C PF14601.1 CBK20161.2 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Epimerase PF01370.16 CBK20162.2 - 1.3e-42 145.8 0.0 1.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBK20162.2 - 1.3e-24 85.8 0.0 2.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBK20162.2 - 2.5e-10 39.5 0.0 3.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK20162.2 - 2.8e-09 36.3 0.0 1.2e-07 30.9 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBK20162.2 - 1.2e-08 35.0 0.0 2.2e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CBK20162.2 - 3.1e-08 32.8 0.0 1e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CBK20162.2 - 3.1e-06 26.2 0.0 4.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBK20162.2 - 3.5e-06 27.1 0.0 6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBK20162.2 - 0.00012 21.7 0.0 0.00033 20.3 0.0 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 CBK20162.2 - 0.0048 17.4 0.0 0.098 13.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 CBK20162.2 - 0.0051 16.0 0.0 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family UQ_con PF00179.21 CBK20163.2 - 1.7e-51 173.3 0.0 1.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK20163.2 - 0.0012 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK20163.2 - 0.025 14.4 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 CBK20163.2 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain ACT_7 PF13840.1 CBK20165.2 - 0.016 14.7 0.9 3.9 7.0 0.0 2.9 2 0 0 2 2 2 0 ACT domain Arm PF00514.18 CBK20165.2 - 0.28 11.0 3.9 0.71 9.7 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cpn60_TCP1 PF00118.19 CBK20166.2 - 4.9e-122 407.9 0.2 5.5e-122 407.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ARPC4 PF05856.7 CBK20167.2 - 5.6e-51 172.2 0.8 6.6e-51 172.0 0.5 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DnaJ PF00226.26 CBK20168.2 - 4.1e-15 55.2 0.0 1.1e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain zf-DNL PF05180.7 CBK20169.2 - 4.7e-31 106.3 0.6 6.3e-31 105.9 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger NLBH PF05211.7 CBK20169.2 - 0.014 14.6 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) RNA_pol_Rpb2_2 PF04561.9 CBK20169.2 - 0.077 12.3 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TFIIS_C PF01096.13 CBK20169.2 - 0.17 11.5 0.7 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GDE_C PF06202.9 CBK20170.2 - 7.3e-83 278.3 0.1 1.3e-82 277.4 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CBK20170.2 - 1.8e-27 96.1 0.9 6.4e-14 51.7 0.3 2.2 2 0 0 2 2 2 2 central domain of human glycogen debranching enzyme hDGE_amylase PF14701.1 CBK20170.2 - 2e-21 76.3 0.0 3.2e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_100 PF12899.2 CBK20170.2 - 0.03 12.7 0.8 4.7 5.4 0.1 2.3 2 0 0 2 2 2 0 Alkaline and neutral invertase HEAT_2 PF13646.1 CBK20171.2 - 4.7e-07 29.9 0.0 0.0018 18.4 0.0 2.7 1 1 2 3 3 3 2 HEAT repeats Arm PF00514.18 CBK20171.2 - 0.00055 19.6 2.3 5 7.1 0.0 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 CBK20171.2 - 0.0022 17.8 0.5 0.0054 16.6 0.1 1.8 2 0 0 2 2 2 1 V-ATPase subunit H CDC14 PF08045.6 CBK20171.2 - 0.0025 16.9 2.6 0.02 13.9 0.0 2.2 1 1 0 2 2 2 1 Cell division control protein 14, SIN component Fes1 PF08609.5 CBK20171.2 - 0.0047 17.3 2.1 0.16 12.4 0.3 2.5 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 CBK20171.2 - 0.021 14.8 0.5 3.1 8.1 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat DUF3554 PF12074.3 CBK20171.2 - 0.033 13.6 4.1 1.1 8.5 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3554) UNC45-central PF11701.3 CBK20171.2 - 0.037 13.6 2.4 0.42 10.2 0.4 2.9 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central RICTOR_V PF14668.1 CBK20171.2 - 0.11 12.3 0.1 15 5.5 0.0 3.0 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Clat_adaptor_s PF01217.15 CBK20173.2 - 6.2e-35 119.9 3.9 6.9e-35 119.8 2.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mnd1 PF03962.10 CBK20174.2 - 0.0048 16.5 3.3 0.0048 16.5 2.3 3.2 2 1 1 3 3 3 2 Mnd1 family Phage_30_3 PF08010.6 CBK20174.2 - 0.042 13.3 0.3 0.042 13.3 0.2 2.0 3 0 0 3 3 3 0 Bacteriophage protein GP30.3 ATG16 PF08614.6 CBK20174.2 - 0.17 11.6 45.5 0.43 10.3 6.2 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 CBK20174.2 - 0.3 11.2 28.6 0.034 14.2 8.2 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 CBK20174.2 - 0.34 10.8 47.8 0.72 9.7 7.2 3.8 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CBK20174.2 - 0.91 9.3 43.1 0.084 12.7 8.2 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 CBK20174.2 - 1.7 6.7 33.7 0.45 8.6 3.1 2.7 1 1 1 3 3 3 0 Plant protein of unknown function (DUF869) DUF4200 PF13863.1 CBK20174.2 - 4.5 7.2 43.3 0.14 12.0 14.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) IncA PF04156.9 CBK20174.2 - 4.6 6.7 48.4 0.27 10.8 11.5 3.1 2 1 1 3 3 3 0 IncA protein RRM_2 PF04059.7 CBK20175.2 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 TFIIA PF03153.8 CBK20175.2 - 4.9 6.9 6.8 6 6.6 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S8e PF01201.17 CBK20176.2 - 2.8e-32 111.6 0.1 3.3e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e ECH PF00378.15 CBK20177.2 - 2.6e-08 33.3 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CBK20177.2 - 0.029 14.5 0.1 0.14 12.3 0.0 2.1 3 0 0 3 3 3 0 2-enoyl-CoA Hydratase C-terminal region zf-RING_4 PF14570.1 CBK20178.2 - 4.8e-18 64.4 16.8 1.2e-17 63.2 11.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CBK20178.2 - 8.7e-05 22.1 10.5 8.7e-05 22.1 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK20178.2 - 0.0033 17.2 12.7 0.0087 15.8 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.17 CBK20178.2 - 0.0063 16.1 0.0 0.36 10.4 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FdhE PF04216.7 CBK20178.2 - 0.087 12.5 5.4 0.14 11.8 3.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation RRM_5 PF13893.1 CBK20178.2 - 0.12 12.1 0.2 1.9 8.3 0.1 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4656 PF15551.1 CBK20178.2 - 0.6 9.2 5.3 1.3 8.1 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4656) zf-RING_5 PF14634.1 CBK20178.2 - 1.6 8.5 15.5 1.8 8.3 8.5 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK20178.2 - 9.6 6.3 19.1 1.4 8.9 10.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 CBK20180.2 - 7e-10 38.0 21.2 0.0016 18.0 0.1 6.5 8 0 0 8 8 8 4 MORN repeat Nucleotid_trans PF03407.11 CBK20181.2 - 5.8e-30 104.6 0.1 8.9e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Aminotran_1_2 PF00155.16 CBK20182.2 - 1.1e-90 304.1 0.0 1.3e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_N PF00288.21 CBK20183.2 - 1.6e-08 34.5 0.0 3.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Myb_DNA-binding PF00249.26 CBK20184.2 - 5e-28 96.8 8.9 3.3e-15 55.8 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK20184.2 - 2.4e-23 82.0 9.4 4.3e-15 55.5 0.7 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CBK20184.2 - 0.0047 17.0 2.4 0.0047 17.0 1.7 3.0 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain SH3BP5 PF05276.9 CBK20184.2 - 0.0099 15.2 0.5 0.016 14.5 0.4 1.4 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) MADF_DNA_bdg PF10545.4 CBK20184.2 - 0.017 15.2 2.6 0.66 10.2 0.3 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PPP5 PF08321.7 CBK20184.2 - 0.16 11.9 1.4 0.54 10.2 0.0 2.6 3 0 0 3 3 3 0 PPP5 TPR repeat region Myb_DNA-bind_5 PF13873.1 CBK20184.2 - 0.23 11.4 0.2 0.23 11.4 0.1 3.3 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CBK20184.2 - 0.43 11.2 5.0 4.2 8.0 0.1 2.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Connexin43 PF03508.8 CBK20184.2 - 4.6 6.5 6.9 0.65 9.2 0.7 2.4 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) PAP_assoc PF03828.14 CBK20185.2 - 1.4e-15 56.9 0.5 2.8e-15 56.0 0.4 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBK20185.2 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PRP38 PF03371.10 CBK20187.2 - 4e-59 199.1 0.0 5.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family TPR_14 PF13428.1 CBK20188.2 - 0.0047 17.4 2.1 0.17 12.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20188.2 - 0.0056 16.5 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Bestrophin PF01062.16 CBK20188.2 - 0.02 13.8 0.4 0.028 13.3 0.3 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel zinc_ribbon_6 PF14599.1 CBK20190.2 - 7.3e-15 54.5 0.2 1.3e-14 53.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon zf-RING_2 PF13639.1 CBK20190.2 - 3.5e-07 29.9 1.9 3.5e-07 29.9 1.3 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBK20190.2 - 3.4e-06 26.6 4.6 1.1e-05 24.9 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20190.2 - 1.6e-05 24.5 7.3 3e-05 23.6 1.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK20190.2 - 3.8e-05 23.6 2.7 3.8e-05 23.6 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBK20190.2 - 9.2e-05 22.4 1.0 9.2e-05 22.4 0.7 1.8 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBK20190.2 - 0.00015 21.3 2.4 0.00015 21.3 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CBK20190.2 - 0.0057 16.9 2.5 2.7 8.5 1.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type PHD PF00628.24 CBK20190.2 - 0.0077 15.8 4.5 0.14 11.8 1.4 2.4 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 CBK20190.2 - 0.06 13.1 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.1 CBK20190.2 - 0.061 13.6 2.2 0.51 10.7 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_UBOX PF13445.1 CBK20190.2 - 0.063 13.0 1.8 0.063 13.0 1.3 2.1 2 1 0 2 2 2 0 RING-type zinc-finger zinc-ribbons_6 PF07191.7 CBK20190.2 - 0.087 12.6 0.3 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons Gin PF10764.4 CBK20190.2 - 0.1 12.3 5.4 2 8.1 0.7 2.7 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin FANCL_C PF11793.3 CBK20190.2 - 0.13 12.2 4.0 0.42 10.6 0.9 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain DZR PF12773.2 CBK20190.2 - 0.14 12.0 2.2 0.48 10.2 1.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 CBK20190.2 - 0.21 11.2 2.3 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger RINGv PF12906.2 CBK20190.2 - 0.23 11.5 2.6 0.3 11.1 0.5 2.1 2 0 0 2 2 2 0 RING-variant domain zf-CHY PF05495.7 CBK20190.2 - 0.27 11.4 2.8 11 6.2 0.5 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-Di19 PF05605.7 CBK20190.2 - 0.3 11.2 1.9 0.6 10.2 0.4 2.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-HYPF PF07503.7 CBK20190.2 - 0.58 9.6 4.8 41 3.7 0.3 3.1 3 0 0 3 3 3 0 HypF finger zf-RING-like PF08746.6 CBK20190.2 - 0.67 9.9 5.8 0.36 10.8 1.2 2.1 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 CBK20190.2 - 0.67 9.5 5.0 0.16 11.6 0.8 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBK20190.2 - 0.82 9.5 6.5 0.39 10.6 1.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2296 PF10058.4 CBK20190.2 - 1.1 9.0 3.6 0.97 9.2 1.1 1.9 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Tnp_zf-ribbon_2 PF13842.1 CBK20190.2 - 5.7 7.4 8.4 0.52 10.7 1.0 2.3 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Peptidase_M48 PF01435.13 CBK20191.2 - 1.8e-39 135.6 0.1 2.5e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 CBK20191.2 - 0.032 13.3 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DAGK_prokar PF01219.14 CBK20191.2 - 0.064 12.8 0.1 0.064 12.8 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Peptidase_M56 PF05569.6 CBK20191.2 - 0.089 11.7 6.4 0.49 9.3 0.0 2.4 1 1 1 2 2 2 0 BlaR1 peptidase M56 RRM_6 PF14259.1 CBK20191.2 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M50 PF02163.17 CBK20191.2 - 3.6 6.4 7.8 2.1 7.2 0.4 2.4 2 0 0 2 2 2 0 Peptidase family M50 PK PF00224.16 CBK20192.2 - 4.2e-127 423.5 2.4 1.2e-126 422.0 0.4 2.0 1 1 1 2 2 2 1 Pyruvate kinase, barrel domain HCaRG PF07258.9 CBK20192.2 - 2.6e-17 62.9 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 HCaRG protein PK_C PF02887.11 CBK20192.2 - 2.5e-08 33.4 0.2 5.8e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CBK20192.2 - 0.0018 17.1 0.0 0.003 16.4 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MIT PF04212.13 CBK20193.2 - 0.038 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_L27e PF01777.13 CBK20194.2 - 6e-19 67.9 7.7 1.2e-18 67.0 5.3 1.5 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBK20194.2 - 2.9e-06 26.7 0.5 5.5e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 KOW motif Scaffolding_pro PF11418.3 CBK20194.2 - 0.11 12.7 0.2 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 Phi29 scaffolding protein DUF974 PF06159.8 CBK20195.2 - 9.8e-09 35.0 0.1 1.4e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) LRR_4 PF12799.2 CBK20196.2 - 6.8e-06 25.5 0.9 0.00022 20.7 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK20196.2 - 6.9e-05 22.5 2.6 0.014 15.1 0.6 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBK20196.2 - 0.0081 16.0 2.6 3.1 8.1 0.4 4.4 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.1 CBK20196.2 - 0.017 15.1 1.8 10 6.5 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 CBK20196.2 - 1.2 9.6 4.0 30 5.4 0.0 4.6 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 CBK20197.2 - 1.5e-16 59.5 29.6 2.2e-06 27.1 3.1 5.6 3 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK20197.2 - 2.5e-10 39.9 28.8 2.4e-08 33.5 5.3 4.4 2 1 3 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 CBK20197.2 - 5.2e-09 34.8 15.6 0.099 12.9 0.0 7.8 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 CBK20197.2 - 3.1e-08 32.8 23.5 0.074 13.1 0.4 7.8 5 3 2 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.28 CBK20197.2 - 3.5e-08 32.3 23.8 0.044 13.8 0.1 7.5 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_2 PF07723.8 CBK20197.2 - 0.95 10.0 6.0 1.3e+02 3.2 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat HSP70 PF00012.15 CBK20198.2 - 1.9e-35 121.9 0.3 1e-33 116.1 0.2 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20198.2 - 7.8e-08 31.2 0.0 2e-06 26.6 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK20198.2 - 1.1e-05 25.2 0.3 0.24 11.2 0.0 3.8 4 0 0 4 4 4 2 Cell division protein FtsA StbA PF06406.6 CBK20198.2 - 0.0022 16.9 0.4 0.19 10.6 0.1 2.9 2 1 0 3 3 3 1 StbA protein DDR PF08841.5 CBK20198.2 - 0.019 13.8 0.0 0.072 11.9 0.0 1.8 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain GLTP PF08718.6 CBK20198.2 - 0.067 13.2 0.1 6.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) MutL PF13941.1 CBK20198.2 - 0.17 10.1 0.1 0.66 8.2 0.0 1.8 2 0 0 2 2 2 0 MutL protein Glyco_transf_49 PF13896.1 CBK20200.2 - 0.00055 19.1 1.7 0.00064 18.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Spexin PF15171.1 CBK20201.2 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Clathrin_lg_ch PF01086.12 CBK20202.2 - 2.1e-17 63.8 16.6 2.6e-17 63.5 11.5 1.1 1 0 0 1 1 1 1 Clathrin light chain Exonuc_VII_L PF02601.10 CBK20202.2 - 0.073 12.2 2.8 0.077 12.1 1.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Caudo_TAP PF02413.12 CBK20202.2 - 0.31 11.1 8.1 0.52 10.4 5.5 1.7 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein AAA_23 PF13476.1 CBK20202.2 - 0.5 10.6 5.9 0.56 10.5 4.1 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBK20202.2 - 5.4 6.5 8.8 7.5 6.1 6.1 1.2 1 0 0 1 1 1 0 IncA protein Hex_IIIa PF02455.11 CBK20202.2 - 7.7 5.0 8.9 8.5 4.9 6.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MORN PF02493.15 CBK20203.2 - 7e-57 185.8 114.3 4.4e-05 22.9 0.2 19.0 19 0 0 19 19 19 18 MORN repeat HSP70 PF00012.15 CBK20203.2 - 8e-25 86.7 0.0 1.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein SGL PF08450.7 CBK20203.2 - 0.07 12.4 0.2 0.16 11.3 0.2 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Lipoprotein_1 PF00820.14 CBK20203.2 - 0.11 11.5 0.4 0.4 9.7 0.3 1.9 2 0 0 2 2 2 0 Borrelia lipoprotein Filament PF00038.16 CBK20204.2 - 0.00014 21.4 31.4 0.00014 21.4 21.8 3.4 1 1 1 2 2 2 1 Intermediate filament protein ADIP PF11559.3 CBK20204.2 - 0.00019 21.3 100.4 0.0031 17.4 8.7 6.5 2 2 4 6 6 6 4 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 CBK20204.2 - 0.00037 20.5 16.7 0.00037 20.5 11.6 5.4 1 1 4 5 5 5 1 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 CBK20204.2 - 0.79 9.5 100.0 1.3 8.8 11.6 5.6 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CBK20204.2 - 0.93 9.3 121.4 1.7 8.4 16.3 6.0 1 1 5 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 CBK20204.2 - 2.8 6.5 97.5 0.1 11.2 19.3 5.2 1 1 4 5 5 5 0 Spc7 kinetochore protein GAS PF13851.1 CBK20204.2 - 6.4 5.9 99.8 3.6 6.7 12.5 5.3 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBK20204.2 - 8.4 5.9 121.3 0.75 9.3 12.0 5.8 1 1 5 6 6 6 0 IncA protein PhaC_N PF07167.8 CBK20204.2 - 9.4 5.6 7.9 4.9 6.5 0.2 3.3 1 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Reo_sigmaC PF04582.7 CBK20204.2 - 9.9 5.2 43.0 0.35 9.9 4.8 5.1 2 2 1 4 4 4 0 Reovirus sigma C capsid protein Ribosomal_L4 PF00573.17 CBK20205.2 - 3e-43 147.4 0.2 5.3e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBK20205.2 - 9.6e-22 76.6 4.4 1.1e-21 76.4 2.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L2_C PF03947.13 CBK20206.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK20206.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HSP70 PF00012.15 CBK20207.2 - 1.6e-202 673.6 4.9 2e-202 673.3 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20207.2 - 2.5e-21 75.6 0.0 2.1e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBK20207.2 - 0.001 18.8 5.9 0.031 14.1 0.8 4.4 4 1 0 4 4 4 1 Cell division protein FtsA Hydantoinase_A PF01968.13 CBK20207.2 - 0.017 14.2 0.6 0.12 11.5 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase CAP59_mtransfer PF11735.3 CBK20207.2 - 0.047 12.9 0.4 0.087 12.0 0.3 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF2922 PF11148.3 CBK20207.2 - 0.062 12.9 0.4 0.33 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Vps53_N PF04100.7 CBK20208.2 - 3.1e-70 236.9 12.2 1.8e-69 234.3 8.4 1.8 1 1 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CBK20208.2 - 0.00046 19.1 5.9 0.00048 19.1 3.4 1.5 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Laminin_II PF06009.7 CBK20208.2 - 0.0011 18.7 3.5 0.0011 18.7 2.4 1.9 1 1 1 2 2 2 1 Laminin Domain II Epsilon_antitox PF08998.6 CBK20208.2 - 0.0096 15.8 0.1 1.1 9.2 0.1 2.8 2 0 0 2 2 2 1 Bacterial epsilon antitoxin Sec5 PF15469.1 CBK20208.2 - 0.039 13.6 3.9 0.07 12.8 2.7 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 AAA_13 PF13166.1 CBK20208.2 - 0.086 11.2 5.2 0.15 10.5 3.6 1.4 1 0 0 1 1 1 0 AAA domain DUF3958 PF13125.1 CBK20208.2 - 0.098 12.5 2.6 2.1 8.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) PRT_C PF08372.5 CBK20208.2 - 0.11 12.0 0.2 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Laminin_I PF06008.9 CBK20208.2 - 0.14 11.4 10.5 0.029 13.7 4.3 2.1 3 0 0 3 3 3 0 Laminin Domain I DUF2884 PF11101.3 CBK20208.2 - 0.19 11.0 6.1 0.11 11.8 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) ING PF12998.2 CBK20208.2 - 0.2 11.9 7.8 0.23 11.7 4.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.6 CBK20208.2 - 0.33 9.5 7.8 0.59 8.7 5.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 CBK20208.2 - 1.7 8.4 6.6 4.6 7.0 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBK20208.2 - 5.3 6.6 15.7 0.068 12.7 4.5 2.5 3 0 0 3 3 3 0 IncA protein DUF724 PF05266.9 CBK20208.2 - 9.6 5.7 10.0 0.55 9.8 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Histone PF00125.19 CBK20209.2 - 9e-24 83.3 0.1 1.1e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20209.2 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFX_C PF14601.1 CBK20209.2 - 0.015 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Histone PF00125.19 CBK20210.2 - 1.8e-17 63.2 0.1 2.3e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK20210.2 - 0.078 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBK20210.2 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Proteasome PF00227.21 CBK20211.2 - 8.1e-17 61.1 0.0 9.4e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit KH_1 PF00013.24 CBK20212.2 - 9.8e-10 37.9 0.3 2.6e-09 36.5 0.1 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CBK20212.2 - 1.8e-06 27.4 0.8 6.2e-06 25.7 0.1 2.3 2 0 0 2 2 2 1 KH domain zf-CCHC_4 PF14392.1 CBK20212.2 - 0.4 10.3 3.0 0.7 9.6 0.3 2.6 3 0 0 3 3 3 0 Zinc knuckle IF-2B PF01008.12 CBK20213.2 - 1.2e-43 149.1 0.2 1.4e-43 148.9 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2096 PF09869.4 CBK20213.2 - 0.057 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) PRKCSH-like PF12999.2 CBK20215.2 - 2.7e-20 72.6 19.4 3e-20 72.5 13.4 1.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Defensin_beta_2 PF13841.1 CBK20215.2 - 0.21 12.0 4.1 0.27 11.6 0.6 2.8 2 1 0 2 2 2 0 Beta defensin Sod_Fe_C PF02777.13 CBK20217.2 - 1.4e-40 137.4 0.7 1.4e-40 137.4 0.5 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBK20217.2 - 1.3e-19 70.2 4.5 7.3e-19 67.8 3.1 2.1 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Aminotran_5 PF00266.14 CBK20219.2 - 3.6e-36 124.6 0.0 5.7e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V CreA PF05981.7 CBK20219.2 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CreA protein DENN PF02141.16 CBK20220.2 - 1.7e-18 67.0 8.4 2.9e-18 66.2 5.8 1.4 1 1 0 1 1 1 1 DENN (AEX-3) domain Peptidase_M41 PF01434.13 CBK20221.2 - 9.2e-62 208.2 0.7 1.5e-61 207.5 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBK20221.2 - 6.9e-44 149.2 0.0 1.5e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK20221.2 - 2.1e-05 24.3 0.0 9.1e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBK20221.2 - 7.5e-05 23.5 0.1 0.00033 21.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK20221.2 - 0.00048 19.8 0.1 0.0016 18.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 CBK20221.2 - 0.00077 19.4 0.1 0.0034 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CBK20221.2 - 0.001 17.8 0.3 0.0042 15.8 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CBK20221.2 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK20221.2 - 0.0016 18.5 0.1 0.052 13.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK20221.2 - 0.0036 17.3 0.1 0.039 13.9 0.1 2.2 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CBK20221.2 - 0.0045 16.0 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBK20221.2 - 0.0055 16.1 0.4 0.018 14.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 CBK20221.2 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBK20221.2 - 0.015 14.4 0.0 0.038 13.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CBK20221.2 - 0.017 14.3 0.0 0.052 12.7 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 CBK20221.2 - 0.018 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBK20221.2 - 0.019 14.0 0.1 0.08 12.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CBK20221.2 - 0.041 14.1 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CBK20221.2 - 0.05 12.7 0.5 0.7 8.9 0.0 2.3 2 0 0 2 2 2 0 KaiC CRA_rpt PF07046.6 CBK20221.2 - 0.13 12.2 2.6 0.48 10.4 1.8 2.0 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Zn_peptidase_2 PF04298.7 CBK20221.2 - 0.24 10.7 0.4 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase UNC-93 PF05978.11 CBK20222.2 - 1e-20 73.8 11.9 1e-20 73.8 8.3 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 CBK20222.2 - 1.6e-11 43.5 33.4 2.1e-11 43.1 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily T_cell_tran_alt PF15128.1 CBK20222.2 - 0.35 10.3 2.6 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 T-cell leukemia translocation-altered Sugar_tr PF00083.19 CBK20222.2 - 0.38 9.2 28.8 3.1e+02 -0.4 20.0 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter UFD1 PF03152.9 CBK20223.2 - 9.7e-37 125.7 0.4 1.2e-36 125.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SLS PF14611.1 CBK20224.2 - 0.055 12.8 7.6 0.1 11.9 0.0 2.9 1 1 1 3 3 3 0 Mitochondrial inner-membrane-bound regulator Fib_alpha PF08702.5 CBK20224.2 - 0.46 10.6 13.1 0.23 11.5 1.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3993 PF13158.1 CBK20224.2 - 0.52 10.1 2.8 0.89 9.3 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3993) Spc24 PF08286.6 CBK20224.2 - 0.96 9.1 12.3 0.085 12.5 2.2 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 KOG2701 PF09762.4 CBK20225.2 - 1.3e-22 80.7 0.0 1.6e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein (DUF2037) FYVE PF01363.16 CBK20226.2 - 4.3e-16 58.5 6.1 4.3e-16 58.5 4.2 2.4 2 1 0 2 2 2 2 FYVE zinc finger zf-SNAP50_C PF12251.3 CBK20226.2 - 0.0065 15.8 2.1 0.0065 15.8 1.4 2.1 2 0 0 2 2 2 2 snRNA-activating protein of 50kDa MW C terminal Thymidylat_synt PF00303.14 CBK20227.2 - 8.2e-114 379.1 0.0 1.1e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 CBK20227.2 - 1.6e-38 131.8 0.1 2.4e-38 131.2 0.1 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase DUF2012 PF09430.5 CBK20229.2 - 0.00029 20.6 0.0 0.00084 19.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DnaJ_CXXCXGXG PF00684.14 CBK20230.2 - 0.00016 21.6 25.0 0.00061 19.7 15.8 2.6 1 1 1 2 2 2 1 DnaJ central domain Pkinase PF00069.20 CBK20232.2 - 8.3e-56 189.0 0.0 9.8e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20232.2 - 4.4e-22 78.3 0.0 1.8e-21 76.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.24 CBK20233.2 - 2.1e-38 131.4 0.1 5.7e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK20233.2 - 1.7e-25 88.6 0.0 4.3e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK20233.2 - 0.00019 21.3 0.2 0.00072 19.4 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Metallophos PF00149.23 CBK20234.2 - 7.8e-24 84.1 0.2 1.2e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 CBK20235.2 - 2.3e-08 33.4 27.7 0.035 13.7 0.3 9.0 7 2 3 10 10 10 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBK20235.2 - 8.7e-07 28.3 33.0 3 8.1 0.0 12.6 13 1 1 14 14 14 3 Leucine Rich repeat LRR_1 PF00560.28 CBK20235.2 - 0.028 14.4 32.7 5.4 7.4 0.0 11.8 12 1 1 13 13 13 0 Leucine Rich Repeat F-box PF00646.28 CBK20235.2 - 0.19 11.4 4.7 0.19 11.4 0.2 2.8 2 0 0 2 2 2 0 F-box domain FAM176 PF14851.1 CBK20236.2 - 0.014 15.0 0.1 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 FAM176 family MFS_1 PF07690.11 CBK20236.2 - 0.014 14.1 0.0 0.014 14.1 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily TEX19 PF15553.1 CBK20236.2 - 0.13 12.1 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 cwf21 PF08312.7 CBK20237.2 - 3.2e-08 33.2 7.5 8.9e-08 31.8 5.2 1.8 1 0 0 1 1 1 1 cwf21 domain XG_FTase PF03254.8 CBK20237.2 - 4.8e-05 22.0 6.5 0.019 13.4 0.0 3.1 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase DUF605 PF04652.11 CBK20237.2 - 1.4 8.2 21.4 1.9 7.8 14.9 1.2 1 0 0 1 1 1 0 Vta1 like EMP24_GP25L PF01105.19 CBK20238.2 - 2e-21 76.5 1.8 2.4e-21 76.3 1.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AOX PF01786.12 CBK20239.2 - 4.3e-62 209.2 0.0 5.6e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_M16 PF00675.15 CBK20240.2 - 8.1e-46 155.4 0.0 1.8e-45 154.3 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBK20240.2 - 2.4e-30 105.5 0.0 7.7e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M44 PF03410.8 CBK20240.2 - 0.012 13.8 0.0 0.12 10.6 0.0 2.0 1 1 0 1 1 1 0 Protein G1 DUF3919 PF13057.1 CBK20240.2 - 0.067 12.6 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Gtr1_RagA PF04670.7 CBK20240.2 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.17 CBK20241.2 - 1.3e-17 63.1 0.0 1.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20241.2 - 4.4e-12 45.8 0.0 5.9e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20241.2 - 4.5e-12 45.6 0.0 6.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NifU_N PF01592.11 CBK20242.2 - 4e-50 168.9 0.1 4.8e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF4061 PF13270.1 CBK20243.2 - 0.00055 19.9 0.9 0.00074 19.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF2272 PF10030.4 CBK20243.2 - 0.021 14.3 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) IF4E PF01652.13 CBK20244.2 - 3.3e-34 117.8 0.0 4.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 14-3-3 PF00244.15 CBK20245.2 - 1.3e-71 240.4 8.4 1.6e-71 240.1 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_11 PF13414.1 CBK20245.2 - 0.0044 16.6 1.0 0.0094 15.5 0.2 1.9 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CBK20245.2 - 0.011 15.7 2.0 0.078 12.9 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat FlaF PF07309.6 CBK20245.2 - 0.054 13.3 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF Gam PF06064.6 CBK20245.2 - 0.12 12.4 2.0 10 6.2 0.2 3.2 2 1 1 3 3 3 0 Host-nuclease inhibitor protein Gam TPR_2 PF07719.12 CBK20245.2 - 0.91 9.5 3.4 3.5 7.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ERCC4 PF02732.10 CBK20247.2 - 8.3e-23 80.7 0.0 1.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_L11_N PF03946.9 CBK20248.2 - 5.9e-14 51.2 0.2 9e-14 50.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBK20248.2 - 2.3e-12 46.8 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Rib_5-P_isom_A PF06026.9 CBK20248.2 - 0.068 12.4 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) STIL_N PF15253.1 CBK20248.2 - 0.14 10.8 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus GHMP_kinases_C PF08544.8 CBK20249.2 - 1.2e-08 34.9 0.0 2.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBK20249.2 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pkinase PF00069.20 CBK20252.2 - 2.4e-17 62.9 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20252.2 - 8.3e-11 41.4 0.0 8.7e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PEP-utilizers PF00391.18 CBK20253.2 - 5.3e-19 67.5 0.4 1e-18 66.6 0.2 1.5 1 1 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF1311 PF07007.7 CBK20253.2 - 0.14 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Spermine_synth PF01564.12 CBK20254.2 - 1.1e-08 34.2 0.2 2.9e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 CBK20254.2 - 4e-07 30.0 0.0 6.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK20254.2 - 9.6e-07 29.3 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK20254.2 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CBK20254.2 - 0.0022 17.0 0.2 0.0046 16.0 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 CBK20254.2 - 0.004 16.5 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBK20254.2 - 0.0075 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBK20254.2 - 0.012 16.4 0.0 0.027 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CBK20254.2 - 0.014 14.4 0.0 0.031 13.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.17 CBK20255.2 - 3.3e-14 52.2 0.0 5.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20255.2 - 9.2e-12 44.7 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20255.2 - 3.1e-07 30.1 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK20255.2 - 0.011 15.6 3.8 0.019 14.8 2.6 1.4 1 0 0 1 1 1 0 RNA binding motif Trypan_PARP PF05887.6 CBK20255.2 - 0.16 11.7 2.2 0.28 10.9 1.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 CBK20255.2 - 9.8 4.5 44.3 0.2 10.0 23.2 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 PA28_beta PF02252.13 CBK20257.2 - 4.8e-41 139.7 0.1 5.1e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Carboxyl_trans PF01039.17 CBK20258.2 - 6.8e-191 634.8 0.1 8.1e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK20258.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Glyco_transf_49 PF13896.1 CBK20259.2 - 3.1e-26 92.2 0.1 1.2e-23 83.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK20259.2 - 0.0057 15.7 0.1 0.084 11.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycophorin_A PF01102.13 CBK20260.2 - 0.0084 15.8 1.0 0.035 13.8 0.7 2.2 1 0 0 1 1 1 1 Glycophorin A EphA2_TM PF14575.1 CBK20260.2 - 0.009 16.3 0.3 0.024 14.9 0.2 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 CBK20260.2 - 0.011 15.4 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family ODV-E18 PF10717.4 CBK20260.2 - 0.014 14.8 0.3 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2561 PF10812.3 CBK20260.2 - 0.017 14.7 1.0 0.026 14.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) LRRC37AB_C PF14914.1 CBK20260.2 - 0.039 13.3 2.6 0.08 12.3 1.8 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF929 PF06053.6 CBK20260.2 - 0.1 11.6 1.7 0.17 10.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) DUF1510 PF07423.6 CBK20260.2 - 0.12 11.7 0.2 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ATP-synt_8 PF00895.15 CBK20260.2 - 0.16 12.1 0.2 0.47 10.6 0.2 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 SP_C-Propep PF08999.5 CBK20260.2 - 0.34 10.3 3.0 0.64 9.5 2.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3827 PF12877.2 CBK20260.2 - 1.1 7.2 2.9 1.6 6.6 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Shisa PF13908.1 CBK20260.2 - 1.7 8.7 29.9 8.3 6.5 19.1 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 CBK20260.2 - 2.5 7.6 5.9 4.7 6.7 4.1 1.4 1 0 0 1 1 1 0 Rifin/stevor family Glyco_hydro_63 PF03200.11 CBK20261.2 - 2.4e-13 48.8 0.0 2.4e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Glyco_hydro_63 PF03200.11 CBK20262.2 - 4.3e-141 471.4 5.0 2.5e-140 468.8 3.5 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase zf-C3HC4_2 PF13923.1 CBK20263.2 - 1.9e-10 40.6 13.3 2.6e-10 40.1 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK20263.2 - 2.8e-10 39.8 10.8 4e-10 39.3 7.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBK20263.2 - 9.8e-10 37.9 10.8 1.3e-09 37.5 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20263.2 - 3e-09 36.4 11.4 4.3e-09 35.9 7.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.9 CBK20263.2 - 4e-06 26.2 8.4 6.2e-06 25.5 3.5 2.2 2 0 0 2 2 2 1 P-11 zinc finger zf-C3HC4 PF00097.20 CBK20263.2 - 1.6e-05 24.4 12.7 2.8e-05 23.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBK20263.2 - 6.7e-05 22.6 3.9 0.0001 22.0 2.7 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CBK20263.2 - 7.9e-05 22.6 9.0 0.00017 21.6 6.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 CBK20263.2 - 0.0002 20.8 8.5 0.00031 20.2 5.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBK20263.2 - 0.00059 19.6 10.5 0.0023 17.7 7.4 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBK20263.2 - 0.0034 17.0 4.9 0.0034 17.0 3.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 CBK20263.2 - 0.0075 15.7 7.4 0.0096 15.4 4.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.7 CBK20263.2 - 0.02 14.0 2.6 0.024 13.8 1.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-TFIIIC PF12660.2 CBK20263.2 - 0.037 13.9 2.8 0.042 13.7 1.9 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex IBR PF01485.16 CBK20263.2 - 0.082 12.7 10.9 0.11 12.4 6.0 2.0 1 1 1 2 2 2 0 IBR domain FYVE PF01363.16 CBK20263.2 - 0.082 12.8 10.9 0.34 10.8 7.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.11 CBK20263.2 - 0.11 12.3 13.7 0.04 13.8 5.5 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 CBK20263.2 - 0.13 12.1 8.9 2 8.3 1.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.24 CBK20263.2 - 0.19 11.4 9.1 0.32 10.7 6.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.1 CBK20263.2 - 0.37 10.5 3.1 0.56 9.9 2.2 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF4637 PF15470.1 CBK20263.2 - 0.5 9.9 3.3 0.69 9.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-Nse PF11789.3 CBK20263.2 - 0.67 9.5 6.0 1.1 8.8 4.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OrfB_Zn_ribbon PF07282.6 CBK20263.2 - 0.74 9.5 7.2 7.8 6.2 2.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-B_box PF00643.19 CBK20263.2 - 1.3 8.9 11.4 0.31 10.9 4.4 2.2 2 1 0 2 2 2 0 B-box zinc finger zf-C2HC5 PF06221.8 CBK20263.2 - 3.2 7.6 11.3 0.79 9.5 5.0 1.9 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-RING_3 PF14369.1 CBK20263.2 - 3.5 7.7 8.5 0.6 10.1 1.4 2.4 1 1 1 2 2 2 0 zinc-finger zf-Apc11 PF12861.2 CBK20263.2 - 4.9 7.0 9.9 20 5.1 6.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LRR_6 PF13516.1 CBK20264.2 - 1.7e-08 33.6 0.8 0.00044 20.0 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CBK20264.2 - 0.0024 17.6 2.3 0.67 10.2 0.5 3.9 2 2 1 3 3 3 1 Leucine Rich Repeat LRR_9 PF14580.1 CBK20264.2 - 0.0049 16.4 2.0 0.014 14.9 0.3 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 CBK20264.2 - 0.027 14.6 1.7 2 8.9 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 CBK20264.2 - 0.05 13.2 6.3 3.5 7.3 2.0 2.8 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF2996 PF11210.3 CBK20264.2 - 0.087 13.1 0.1 19 5.5 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2996) DUF1854 PF08909.6 CBK20264.2 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) XdhC_CoxI PF02625.11 CBK20264.2 - 0.13 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 XdhC and CoxI family AAA PF00004.24 CBK20265.2 - 3.4e-30 104.9 0.0 1.8e-28 99.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK20265.2 - 3.1e-09 37.0 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK20265.2 - 3.1e-07 31.2 0.0 5.2e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK20265.2 - 5.8e-06 26.4 0.3 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CBK20265.2 - 1.5e-05 25.2 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK20265.2 - 1.6e-05 24.6 0.0 0.0002 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBK20265.2 - 3.8e-05 23.5 0.0 6.8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBK20265.2 - 5e-05 22.3 0.0 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBK20265.2 - 5.3e-05 23.1 0.0 9.2e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBK20265.2 - 6.9e-05 22.5 0.1 0.00024 20.7 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 CBK20265.2 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 CBK20265.2 - 0.0003 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBK20265.2 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase KAP_NTPase PF07693.9 CBK20265.2 - 0.00078 18.5 0.0 0.5 9.3 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_28 PF13521.1 CBK20265.2 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBK20265.2 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 CBK20265.2 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBK20265.2 - 0.0023 17.1 0.0 0.0096 15.1 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBK20265.2 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBK20265.2 - 0.0037 16.8 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBK20265.2 - 0.0037 16.3 0.1 0.0091 15.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CBK20265.2 - 0.0041 16.8 0.1 0.24 11.0 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 CBK20265.2 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CBK20265.2 - 0.0071 15.0 0.3 0.011 14.4 0.2 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CBK20265.2 - 0.0071 15.1 0.0 0.0098 14.6 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CBK20265.2 - 0.015 15.2 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 CBK20265.2 - 0.017 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 CBK20265.2 - 0.019 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CBK20265.2 - 0.025 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 CBK20265.2 - 0.026 14.1 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 CBK20265.2 - 0.028 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBK20265.2 - 0.032 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 CBK20265.2 - 0.038 13.4 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CBK20265.2 - 0.052 12.7 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.4 CBK20265.2 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 CBK20265.2 - 0.066 12.1 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 CBK20265.2 - 0.084 12.5 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 1 0 NTPase AAA_10 PF12846.2 CBK20265.2 - 0.088 12.2 0.0 0.93 8.8 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain KaiC PF06745.8 CBK20265.2 - 0.096 11.7 0.1 0.91 8.5 0.0 2.0 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 CBK20265.2 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CBK20265.2 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pinin_SDK_memA PF04696.8 CBK20266.2 - 3.9e-07 29.7 4.3 2.6e-05 23.8 0.3 6.6 2 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region DUF945 PF06097.6 CBK20267.2 - 0.23 10.1 0.5 0.32 9.7 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) ABC_membrane PF00664.18 CBK20268.2 - 8.5e-58 195.9 34.4 8.1e-31 107.4 9.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBK20268.2 - 9e-53 178.2 0.5 1.6e-29 102.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CBK20268.2 - 5.4e-09 35.6 13.8 0.0055 15.9 0.3 4.7 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK20268.2 - 2.6e-08 34.1 0.2 0.21 11.4 0.0 4.7 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK20268.2 - 1.8e-06 27.2 0.0 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBK20268.2 - 9.2e-06 25.7 1.2 0.12 12.3 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.18 CBK20268.2 - 3.6e-05 23.6 4.1 0.013 15.3 0.0 3.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 CBK20268.2 - 3.9e-05 23.5 4.5 0.022 14.7 0.0 3.0 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CBK20268.2 - 0.00014 21.2 0.2 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CBK20268.2 - 0.00042 19.7 0.0 0.055 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBK20268.2 - 0.0017 18.7 14.2 0.006 16.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 CBK20268.2 - 0.002 18.6 11.1 0.62 10.5 0.0 4.5 5 0 0 5 5 4 2 Miro-like protein Zeta_toxin PF06414.7 CBK20268.2 - 0.0037 16.4 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.8 CBK20268.2 - 0.005 15.8 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sec62 PF03839.11 CBK20268.2 - 0.017 14.5 0.2 0.049 13.0 0.2 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_10 PF12846.2 CBK20268.2 - 0.024 14.0 0.0 6.1 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 CBK20268.2 - 0.032 13.2 0.0 0.032 13.2 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 CBK20268.2 - 0.037 13.8 3.2 0.46 10.2 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 CBK20268.2 - 0.041 14.0 0.2 8.7 6.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBK20268.2 - 0.045 13.9 0.2 15 5.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBK20268.2 - 0.068 13.9 0.0 21 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CBK20268.2 - 0.12 11.7 1.7 0.88 8.9 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CBK20270.2 - 2.7e-53 180.3 0.0 5e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CBK20270.2 - 6.5e-38 130.7 9.2 1.2e-37 129.8 6.4 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CBK20270.2 - 6.5e-07 28.9 3.3 6.5e-07 28.9 0.2 2.5 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 CBK20270.2 - 3.8e-06 26.9 0.4 2.3e-05 24.4 0.4 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 CBK20270.2 - 6.9e-06 25.0 0.0 2.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 CBK20270.2 - 0.00015 21.8 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CBK20270.2 - 0.00093 18.9 0.0 0.39 10.4 0.0 2.9 2 1 1 3 3 3 1 NTPase MobB PF03205.9 CBK20270.2 - 0.0022 17.6 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CoA_binding_2 PF13380.1 CBK20270.2 - 0.0025 17.9 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 1 CoA binding domain DAP3 PF10236.4 CBK20270.2 - 0.003 16.5 0.1 0.0063 15.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CBK20270.2 - 0.0033 17.4 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 CBK20270.2 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TerB-C PF15615.1 CBK20270.2 - 0.013 15.7 0.7 0.013 15.7 0.5 2.7 1 1 1 2 2 1 0 TerB-C domain FKBP_N PF01346.13 CBK20270.2 - 0.15 12.0 3.4 5.1 7.1 2.2 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GAGA_bind PF06217.7 CBK20270.2 - 4.9 7.0 8.3 7.3 6.4 5.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DnaJ PF00226.26 CBK20271.2 - 1e-28 98.8 6.0 1e-28 98.8 4.1 3.1 4 0 0 4 4 2 1 DnaJ domain TPR_11 PF13414.1 CBK20271.2 - 1e-23 82.7 16.1 7.1e-11 41.5 0.5 5.6 4 2 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 CBK20271.2 - 2.1e-19 67.7 11.3 4.2e-05 23.1 0.1 7.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBK20271.2 - 5.4e-17 60.5 17.7 0.0061 16.1 0.1 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20271.2 - 2.3e-14 53.0 12.5 2.3e-05 24.2 0.3 5.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20271.2 - 7.4e-14 51.0 0.0 0.0075 16.8 0.1 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20271.2 - 8.9e-14 51.7 1.5 0.0033 18.0 0.0 5.2 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK20271.2 - 1.6e-12 47.5 11.1 0.00012 22.2 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBK20271.2 - 1.2e-09 38.0 9.9 0.024 15.0 0.0 6.8 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK20271.2 - 2.5e-09 36.2 13.0 0.00015 21.2 0.0 7.2 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK20271.2 - 1.3e-05 25.2 25.7 0.014 15.5 2.4 4.9 4 2 2 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBK20271.2 - 1.9e-05 24.0 14.3 0.016 14.9 0.1 6.0 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK20271.2 - 2.2e-05 24.3 6.1 0.21 11.8 0.0 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK20271.2 - 2.6e-05 23.9 0.6 0.98 9.3 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBK20271.2 - 7.6e-05 22.5 1.3 0.022 14.6 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBK20271.2 - 0.013 15.5 11.8 0.87 9.7 0.9 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Apc5 PF12862.2 CBK20271.2 - 0.021 14.6 0.8 3.6 7.4 0.4 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Alkyl_sulf_dimr PF14863.1 CBK20271.2 - 0.03 14.5 4.9 0.29 11.3 0.9 3.4 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation FlbT PF07378.6 CBK20271.2 - 0.049 13.4 4.0 6.6 6.6 0.6 3.7 2 1 1 3 3 3 0 Flagellar protein FlbT DUF3366 PF11846.3 CBK20271.2 - 0.066 13.0 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Erf4 PF10256.4 CBK20271.2 - 0.085 12.7 0.5 0.7 9.7 0.0 2.6 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Glyco_hyd_65N_2 PF14498.1 CBK20271.2 - 0.12 12.0 1.4 5.3 6.6 0.2 2.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain TPR_4 PF07721.9 CBK20271.2 - 0.25 11.8 1.7 2.4 8.8 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat NEMO PF11577.3 CBK20271.2 - 0.88 9.3 7.8 0.9 9.3 0.5 3.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO ADP_ribosyl_GH PF03747.9 CBK20271.2 - 0.91 9.2 2.6 2.8 7.6 1.8 1.9 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase TPR_3 PF07720.7 CBK20271.2 - 0.98 9.2 10.6 16 5.4 0.9 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat FUN14 PF04930.10 CBK20271.2 - 1.1 9.5 6.0 11 6.4 0.0 4.5 4 2 1 5 5 2 0 FUN14 family DUF4363 PF14276.1 CBK20271.2 - 1.4 8.6 13.9 2.3 7.9 0.7 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4363) DUF964 PF06133.6 CBK20271.2 - 1.8 8.5 22.1 1.6 8.7 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF964) PTN_MK_C PF01091.13 CBK20271.2 - 3.2 7.7 7.7 0.21 11.5 0.6 2.7 3 0 0 3 3 1 0 PTN/MK heparin-binding protein family, C-terminal domain DUF1771 PF08590.5 CBK20272.2 - 5.7e-18 64.6 9.0 9.5e-18 63.9 6.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 CBK20272.2 - 8.3e-13 48.3 0.2 1.9e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Smr domain Methyltransf_24 PF13578.1 CBK20272.2 - 0.04 14.7 0.0 0.058 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2450 PF10475.4 CBK20273.2 - 0.0003 19.8 0.2 0.0016 17.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Snapin_Pallidin PF14712.1 CBK20273.2 - 0.1 12.8 4.1 0.91 9.8 0.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Vps54 PF07928.7 CBK20274.2 - 1.5e-25 89.9 0.9 1.5e-25 89.9 0.7 2.0 2 0 0 2 2 2 1 Vps54-like protein PLRV_ORF5 PF01690.12 CBK20275.2 - 0.00018 20.7 8.9 0.0003 20.0 6.2 1.2 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein LRR_8 PF13855.1 CBK20275.2 - 0.25 11.1 12.4 1.1 9.1 0.5 4.5 4 1 1 5 5 5 0 Leucine rich repeat GBP PF02263.14 CBK20276.2 - 1.2e-36 126.0 0.0 1.6e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MFS_1 PF07690.11 CBK20277.2 - 1.7e-43 148.7 24.1 1.3e-31 109.6 9.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK20277.2 - 8.1e-14 51.0 28.0 2.2e-13 49.5 19.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CBK20277.2 - 4.3e-06 25.2 4.0 4.3e-06 25.2 2.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 CBK20277.2 - 0.0047 16.7 0.2 0.018 14.8 0.1 2.0 1 0 0 1 1 1 1 MFS_1 like family FAM176 PF14851.1 CBK20277.2 - 0.0054 16.4 0.1 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 FAM176 family AXH PF08517.7 CBK20277.2 - 2.5 8.3 5.0 31 4.7 0.0 3.1 4 0 0 4 4 4 0 Ataxin-1 and HBP1 module (AXH) NUC153 PF08159.7 CBK20278.2 - 1.2e-11 43.9 0.5 2.6e-11 42.9 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 CBK20278.2 - 0.0015 18.3 0.0 3.8 7.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Radical_SAM PF04055.16 CBK20279.2 - 2e-19 70.3 0.2 2e-19 70.3 0.1 2.3 3 1 0 3 3 3 1 Radical SAM superfamily Wyosine_form PF08608.7 CBK20279.2 - 4.3e-18 65.1 0.0 1.7e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation DUF668 PF05003.7 CBK20279.2 - 0.00095 19.3 0.1 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF668) Na_sulph_symp PF00939.14 CBK20280.2 - 1.8e-78 264.5 37.6 2.2e-78 264.2 26.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBK20280.2 - 2.2e-22 79.0 44.4 1.5e-14 53.4 9.3 3.1 1 1 2 3 3 3 3 Citrate transporter DctM PF06808.7 CBK20280.2 - 1.1e-06 27.5 30.5 3.5e-06 25.8 9.7 2.3 2 0 0 2 2 2 2 DctM-like transporters tRNA-synt_2d PF01409.15 CBK20281.2 - 7.3e-84 280.8 0.0 1e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBK20281.2 - 1.7e-07 30.9 0.1 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CBK20281.2 - 1.5e-05 23.9 0.1 5.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) MarR PF01047.17 CBK20281.2 - 0.0013 18.4 0.0 0.0046 16.6 0.0 1.9 1 0 0 1 1 1 1 MarR family Ribonuc_red_lgC PF02867.10 CBK20282.2 - 1.4e-09 37.1 0.0 0.0027 16.3 0.0 3.2 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBK20282.2 - 0.00016 21.3 0.0 0.00038 20.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain TFIIF_alpha PF05793.7 CBK20283.2 - 0.25 9.6 31.0 0.29 9.4 21.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOBP PF15279.1 CBK20283.2 - 1.1 9.5 8.7 1.4 9.1 6.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RRM_1 PF00076.17 CBK20284.2 - 7e-05 22.3 0.0 0.00024 20.6 0.0 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_2 PF07486.7 CBK20284.2 - 0.0058 17.1 0.0 0.0075 16.7 0.0 1.2 1 0 0 1 1 1 1 Cell Wall Hydrolase RRM_6 PF14259.1 CBK20284.2 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20284.2 - 0.027 14.3 0.0 0.16 11.8 0.0 2.2 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S27e PF01667.12 CBK20285.2 - 1.9e-24 84.9 4.6 2.5e-24 84.5 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CBK20285.2 - 7e-05 22.6 1.3 9.2e-05 22.2 0.9 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CBK20285.2 - 0.02 14.2 2.6 0.031 13.5 1.8 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding FYVE_2 PF02318.11 CBK20285.2 - 0.09 12.6 0.5 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-NADH-PPase PF09297.6 CBK20285.2 - 0.11 12.0 1.6 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.1 CBK20285.2 - 0.18 11.4 1.7 9.4 6.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK20285.2 - 0.3 10.7 1.7 12 5.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 CBK20285.2 - 0.3 10.1 2.9 2 7.5 0.0 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.1 CBK20285.2 - 1 8.6 4.3 1.3 8.3 2.1 1.8 1 1 1 2 2 2 0 zinc-ribbon domain Acetyltransf_1 PF00583.19 CBK20286.2 - 9e-16 57.6 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBK20286.2 - 4.5e-08 33.1 0.1 8.2e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK20286.2 - 5.4e-07 29.2 0.0 8.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBK20286.2 - 2.2e-06 27.7 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBK20286.2 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBK20286.2 - 0.00042 20.5 0.0 0.00074 19.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK20286.2 - 0.0011 18.9 0.2 0.0023 17.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBK20286.2 - 0.0041 17.0 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HGD-D PF06050.8 CBK20286.2 - 0.024 13.4 0.3 0.028 13.2 0.2 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF3749 PF12568.3 CBK20286.2 - 0.095 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MORN PF02493.15 CBK20287.2 - 8.1e-10 37.8 8.9 0.027 14.1 0.0 4.5 4 0 0 4 4 4 4 MORN repeat HSP70 PF00012.15 CBK20288.2 - 3.5e-13 48.3 0.0 6.7e-13 47.4 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein Histone PF00125.19 CBK20289.2 - 8.5e-33 112.3 0.8 1.3e-32 111.6 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK20289.2 - 5.6e-05 23.2 0.1 9.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20289.2 - 0.0096 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK20290.2 - 9.7e-15 54.4 0.1 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBK20290.2 - 6e-05 22.9 0.1 8.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CBK20290.2 - 8.1e-05 22.7 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20290.2 - 0.00075 19.5 0.1 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBK20290.2 - 0.016 14.9 0.1 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HTH_17 PF12728.2 CBK20290.2 - 0.048 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-31kDa PF02291.10 CBK20290.2 - 0.07 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 CBK20290.2 - 0.15 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SMN PF06003.7 CBK20291.2 - 2.1e-12 46.7 4.2 6.3e-08 32.0 0.1 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) TUDOR PF00567.19 CBK20291.2 - 1.4e-05 24.9 2.9 0.0026 17.5 0.2 3.1 1 1 2 3 3 3 2 Tudor domain Borrelia_P83 PF05262.6 CBK20292.2 - 0.34 9.1 17.2 0.4 8.9 11.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.12 CBK20292.2 - 0.83 9.4 6.1 0.96 9.1 4.2 1.2 1 0 0 1 1 1 0 DDHD domain CT47 PF15623.1 CBK20292.2 - 1.6 8.3 22.1 2 8.0 15.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Herpes_UL17 PF04559.7 CBK20292.2 - 3.6 6.0 6.5 3.3 6.2 2.5 1.4 1 1 1 2 2 2 0 Herpesvirus UL17 protein DUF2992 PF11208.3 CBK20292.2 - 7.1 6.5 17.5 17 5.3 12.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pkinase PF00069.20 CBK20293.2 - 1.1e-23 83.7 0.0 8.8e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20293.2 - 3.4e-20 72.1 0.0 3.2e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF605 PF04652.11 CBK20293.2 - 0.021 14.2 20.5 0.026 13.9 14.2 1.1 1 0 0 1 1 1 0 Vta1 like Kinase-like PF14531.1 CBK20293.2 - 0.094 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RCC1 PF00415.13 CBK20294.2 - 4.4e-28 97.2 16.1 1e-09 38.4 0.0 7.3 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK20294.2 - 1.6e-18 65.7 27.5 4e-06 26.2 0.0 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF3548 PF12068.3 CBK20294.2 - 0.032 13.5 1.9 0.05 12.8 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Hom_end_hint PF05203.11 CBK20294.2 - 0.74 9.5 3.6 0.59 9.8 1.4 1.5 2 0 0 2 2 2 0 Hom_end-associated Hint DUF1510 PF07423.6 CBK20294.2 - 1.5 8.1 11.9 2.3 7.5 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Acylphosphatase PF00708.13 CBK20295.2 - 1.5e-07 31.4 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase WD40 PF00400.27 CBK20296.2 - 7.8e-24 82.6 4.0 1.7e-07 30.8 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBK20296.2 - 0.0073 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region DUF3312 PF11768.3 CBK20296.2 - 0.014 13.6 0.2 0.56 8.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) DUF2203 PF09969.4 CBK20297.2 - 1.8 8.7 0.1 3.8e+02 1.2 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) DNA_pol_B_2 PF03175.8 CBK20298.2 - 8.5e-09 34.5 7.8 0.0019 16.9 0.1 3.6 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Vac14_Fig4_bd PF11916.3 CBK20299.2 - 3.6e-12 45.8 0.2 6.6e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding HEAT_2 PF13646.1 CBK20299.2 - 1.5e-09 37.9 0.4 0.026 14.7 0.0 3.8 2 2 1 3 3 3 3 HEAT repeats CLASP_N PF12348.3 CBK20299.2 - 8.4e-08 31.8 0.1 7e-07 28.8 0.0 2.4 2 2 1 3 3 3 1 CLASP N terminal HEAT PF02985.17 CBK20299.2 - 9e-07 28.4 4.1 0.017 15.1 0.1 5.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.2 CBK20299.2 - 6.7e-06 26.0 2.1 0.72 9.6 0.1 3.4 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBK20299.2 - 0.003 17.9 2.8 0.75 10.3 0.1 3.8 3 1 0 3 3 3 1 HEAT-like repeat ParcG PF10274.4 CBK20299.2 - 0.0058 16.5 3.7 0.32 10.8 0.0 3.7 2 2 1 4 4 4 1 Parkin co-regulated protein DRIM PF07539.7 CBK20299.2 - 0.38 10.1 5.3 6.8 6.1 0.0 3.5 3 1 1 4 4 4 0 Down-regulated in metastasis Vac14_Fab1_bd PF12755.2 CBK20300.2 - 8.9e-33 112.5 0.3 2.8e-32 110.9 0.1 1.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CBK20300.2 - 2e-09 36.7 0.0 5.3e-05 22.9 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat DUF2454 PF10521.4 CBK20300.2 - 6.7e-05 22.0 0.0 7.5e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT_2 PF13646.1 CBK20300.2 - 0.00011 22.3 0.0 0.002 18.3 0.0 2.1 1 1 0 1 1 1 1 HEAT repeats CLASP_N PF12348.3 CBK20300.2 - 0.0031 16.8 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Adaptin_N PF01602.15 CBK20300.2 - 0.0064 14.8 0.3 0.87 7.8 0.0 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 CBK20300.2 - 0.028 14.8 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat Thioredoxin PF00085.15 CBK20301.2 - 2.8e-27 94.4 0.1 7.3e-27 93.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin WD40 PF00400.27 CBK20301.2 - 2.5e-07 30.3 0.4 9e-07 28.5 0.3 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Thioredoxin_2 PF13098.1 CBK20301.2 - 3.5e-07 30.4 0.0 3e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK20301.2 - 2.4e-06 27.5 0.0 0.0023 18.0 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBK20301.2 - 2.9e-05 23.9 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBK20301.2 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 CBK20301.2 - 0.047 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.6 CBK20301.2 - 0.048 13.5 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 CBK20301.2 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Arf PF00025.16 CBK20302.2 - 5.1e-60 201.6 0.0 5.7e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBK20302.2 - 1.2e-12 47.3 0.3 5.3e-10 38.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBK20302.2 - 9.2e-12 44.6 0.0 2.9e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBK20302.2 - 9.6e-10 39.0 0.0 1.5e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK20302.2 - 2.9e-07 30.4 0.0 1.1e-06 28.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK20302.2 - 7e-07 28.6 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBK20302.2 - 1.6e-06 27.4 0.0 3.1e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBK20302.2 - 2e-05 24.1 0.0 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBK20302.2 - 0.053 13.0 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CBK20302.2 - 0.059 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.14 CBK20302.2 - 0.077 12.4 0.1 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CBK20302.2 - 0.1 11.5 0.1 17 4.2 0.0 2.6 2 1 1 3 3 3 0 Septin Glyco_transf_8 PF01501.15 CBK20303.2 - 2.8e-24 85.8 1.5 2.4e-23 82.7 1.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CBK20303.2 - 0.00045 19.6 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Ribosomal_L7Ae PF01248.21 CBK20303.2 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HSP70 PF00012.15 CBK20304.2 - 5.5e-17 60.9 0.0 4.4e-16 57.9 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MMR_HSR1 PF01926.18 CBK20306.2 - 4.5e-18 65.3 0.0 1.3e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CBK20306.2 - 1.4e-14 53.6 0.0 2.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CBK20306.2 - 6.6e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBK20306.2 - 4.8e-05 23.2 0.3 0.027 14.3 0.0 2.7 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 CBK20306.2 - 0.00061 20.2 0.0 0.0035 17.8 0.0 2.3 3 1 0 3 3 3 1 Miro-like protein AAA_28 PF13521.1 CBK20306.2 - 0.011 15.6 0.1 0.095 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain GPAT_N PF14829.1 CBK20306.2 - 0.017 14.8 0.2 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_16 PF13191.1 CBK20306.2 - 0.04 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Proteasome PF00227.21 CBK20307.2 - 4.6e-53 179.3 0.0 5.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK20307.2 - 4.8e-15 54.5 0.3 9.7e-15 53.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CS PF04969.11 CBK20308.2 - 7.9e-12 45.5 0.3 2e-09 37.8 0.2 2.5 2 1 0 2 2 2 1 CS domain Ras PF00071.17 CBK20309.2 - 1.6e-59 199.8 0.4 1.9e-59 199.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK20309.2 - 4e-18 66.0 0.1 6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK20309.2 - 5.2e-16 58.3 0.0 6.4e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK20309.2 - 8.4e-08 31.6 0.1 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBK20309.2 - 1.2e-05 24.6 0.1 0.056 12.7 0.0 2.0 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CBK20309.2 - 1.3e-05 25.1 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CBK20309.2 - 4.4e-05 22.7 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 CBK20309.2 - 4.6e-05 22.9 0.0 0.00022 20.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CBK20309.2 - 0.0094 15.6 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 CBK20309.2 - 0.014 14.6 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBK20309.2 - 0.037 13.5 0.0 0.46 9.9 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 CBK20309.2 - 0.069 13.0 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBK20309.2 - 0.071 13.2 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 CBK20310.2 - 2e-40 138.0 14.4 4e-40 137.0 10.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Colicin_V PF02674.11 CBK20310.2 - 0.024 14.4 1.1 0.045 13.5 0.8 1.4 1 0 0 1 1 1 0 Colicin V production protein 7TMR-DISM_7TM PF07695.6 CBK20310.2 - 0.19 11.3 8.5 0.034 13.8 3.5 1.5 2 0 0 2 2 2 0 7TM diverse intracellular signalling DZR PF12773.2 CBK20310.2 - 1 9.2 12.2 0.4 10.5 6.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 CBK20311.2 - 7.2e-34 114.4 23.9 6.2e-12 44.9 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBK20311.2 - 0.00041 19.2 1.6 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like Apc4_WD40 PF12894.2 CBK20311.2 - 0.0041 16.5 0.0 0.3 10.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 CBK20311.2 - 0.0095 13.8 0.6 1.2 6.8 0.1 2.9 3 0 0 3 3 3 2 IKI3 family DUF3312 PF11768.3 CBK20311.2 - 0.05 11.8 0.0 4.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) WD40 PF00400.27 CBK20312.2 - 2.3e-08 33.5 0.9 7.7e-07 28.7 0.6 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CBK20312.2 - 0.0042 17.3 1.6 0.44 10.8 0.1 2.4 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 CBK20312.2 - 0.048 11.7 0.0 0.054 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1381 PF07129.6 CBK20312.2 - 0.77 9.2 2.6 1.9 7.9 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1381) HSP70 PF00012.15 CBK20313.2 - 7.7e-66 222.2 0.0 1.8e-65 221.0 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20313.2 - 7.3e-11 41.2 0.1 9e-05 21.2 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein DDR PF08841.5 CBK20313.2 - 0.0057 15.5 0.0 0.91 8.2 0.0 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBK20313.2 - 0.0074 15.2 0.0 0.16 10.9 0.0 2.3 2 0 0 2 2 2 1 StbA protein Band_7 PF01145.20 CBK20314.2 - 1.3e-22 80.5 2.9 1.5e-22 80.3 1.1 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family Carboxyl_trans PF01039.17 CBK20315.2 - 9e-143 476.1 0.0 1.1e-142 475.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CRAL_TRIO PF00650.15 CBK20316.2 - 3.3e-26 91.6 0.2 5e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBK20316.2 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RNA_pol_Rbc25 PF08292.7 CBK20316.2 - 0.071 13.3 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 RNA_pol_Rpb2_6 PF00562.23 CBK20317.2 - 5.7e-110 367.6 0.0 7.7e-110 367.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBK20317.2 - 1.7e-30 105.4 0.0 2.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBK20317.2 - 1.4e-23 82.4 0.0 2.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CBK20317.2 - 8.5e-23 80.7 0.1 1.3e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CBK20317.2 - 2.6e-20 72.4 0.0 7.4e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 CBK20317.2 - 1.5e-11 44.0 0.0 4.1e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_5 PF04567.12 CBK20317.2 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Herpes_UL45 PF05473.7 CBK20318.2 - 0.012 15.0 0.1 0.012 15.0 0.0 3.9 3 1 0 3 3 3 0 UL45 protein Mito_carr PF00153.22 CBK20319.2 - 1.1e-30 105.1 4.2 4.5e-10 39.0 0.0 4.5 3 2 1 4 4 4 4 Mitochondrial carrier protein Ribosomal_S11 PF00411.14 CBK20320.2 - 2.5e-41 140.2 0.3 3.2e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 CBK20320.2 - 0.031 13.1 0.1 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 CBK20320.2 - 0.077 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Condensin2nSMC PF12422.3 CBK20321.2 - 4.9e-14 52.3 0.3 1.4e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 CBK20321.2 - 1e-07 31.4 2.6 0.3 11.2 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBK20321.2 - 2.6e-05 24.1 1.3 0.0005 19.9 0.1 2.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBK20321.2 - 0.0075 14.6 0.4 0.063 11.5 0.0 2.0 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 CBK20321.2 - 0.011 15.9 0.1 3.6 7.9 0.1 3.0 2 1 1 3 3 3 0 HEAT repeats Toxin_4 PF00706.12 CBK20321.2 - 0.044 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin RNA_pol_A_bac PF01000.21 CBK20322.2 - 3.2e-25 88.4 0.5 1.5e-24 86.3 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBK20322.2 - 5.7e-16 57.4 0.0 8e-16 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 CBK20322.2 - 0.065 12.6 0.0 14 5.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain G-patch PF01585.18 CBK20323.2 - 1.4e-11 43.9 4.1 2.9e-11 42.9 2.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK20323.2 - 5.3e-05 22.9 1.9 5.7e-05 22.8 0.6 1.6 1 1 0 1 1 1 1 DExH-box splicing factor binding site AAA_34 PF13872.1 CBK20324.2 - 7.2e-97 323.8 0.0 1.1e-96 323.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 CBK20324.2 - 1.1e-76 257.9 1.8 1.3e-67 228.1 0.1 3.1 3 1 0 4 4 4 2 Helicase_C-like Helicase_C PF00271.26 CBK20324.2 - 0.00069 19.4 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MIS13 PF08202.6 CBK20324.2 - 0.0037 16.3 0.4 0.0037 16.3 0.3 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family DUF2042 PF09743.4 CBK20325.2 - 4.2e-58 196.7 3.3 7.5e-58 195.9 2.3 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) HTH_24 PF13412.1 CBK20325.2 - 0.011 15.0 5.1 0.021 14.1 0.0 3.4 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 CBK20325.2 - 0.015 14.9 0.0 0.36 10.5 0.0 2.8 2 0 0 2 2 2 0 MarR family HTH_11 PF08279.7 CBK20325.2 - 0.1 12.2 0.2 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 HTH domain HTH_27 PF13463.1 CBK20325.2 - 0.12 12.7 1.1 6.6 7.1 0.0 3.3 4 0 0 4 4 4 0 Winged helix DNA-binding domain DUF413 PF04219.7 CBK20326.2 - 0.035 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF WD40 PF00400.27 CBK20327.2 - 4.5e-60 197.5 18.6 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK20327.2 - 4.3e-05 21.8 8.9 0.0062 14.7 0.1 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK20327.2 - 0.002 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK20327.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK20327.2 - 0.0071 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK20327.2 - 0.011 14.6 0.2 0.45 9.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Gmad1 PF10647.4 CBK20327.2 - 0.067 12.5 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK20327.2 - 0.068 13.4 0.1 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Ribosomal_L37e PF01907.14 CBK20328.2 - 1.9e-26 91.5 11.2 1.9e-26 91.5 7.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CBK20328.2 - 0.0026 17.5 1.2 0.0039 16.9 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon AMOP PF03782.12 CBK20328.2 - 0.014 15.4 0.3 0.016 15.2 0.2 1.0 1 0 0 1 1 1 0 AMOP domain HypA PF01155.14 CBK20328.2 - 0.097 12.3 0.4 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 CBK20328.2 - 0.28 10.4 1.6 11 5.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S14 PF00253.16 CBK20328.2 - 0.29 10.5 9.4 3.5 7.0 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e LRR_6 PF13516.1 CBK20329.2 - 2e-10 39.6 6.8 4.3e-05 23.1 0.2 3.7 3 1 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 CBK20329.2 - 1.4e-06 27.7 7.9 3.8e-06 26.3 1.0 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK20329.2 - 0.0051 16.5 4.8 0.2 11.4 0.6 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CBK20329.2 - 0.019 15.0 7.0 5.7 7.5 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CBK20329.2 - 0.069 13.2 13.0 0.83 9.9 0.4 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.1 CBK20329.2 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 Leucine-rich repeat Ovate PF04844.8 CBK20330.2 - 0.062 13.1 2.3 0.063 13.0 0.2 2.1 1 1 1 2 2 2 0 Transcriptional repressor, ovate WD40 PF00400.27 CBK20332.2 - 7.1e-08 32.0 4.1 0.0038 17.0 0.3 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat BAR PF03114.13 CBK20333.2 - 0.025 14.0 0.1 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 BAR domain NT5C PF06941.7 CBK20334.2 - 4.9e-11 42.5 0.1 9.5e-11 41.5 0.0 1.4 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 CBK20334.2 - 0.00034 20.8 0.0 0.00048 20.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 CBK20334.2 - 0.046 13.3 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Trehalose_PPase PF02358.11 CBK20334.2 - 0.061 12.2 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase zf-Tim10_DDP PF02953.10 CBK20335.2 - 9.6e-08 31.2 0.4 1.1e-07 31.0 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4372 PF14294.1 CBK20335.2 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4372) Pro_isomerase PF00160.16 CBK20336.2 - 1.9e-44 151.5 0.2 2.1e-44 151.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD S_100 PF01023.14 CBK20337.2 - 0.1 11.9 0.2 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Adap_comp_sub PF00928.16 CBK20338.2 - 2.1e-82 276.2 0.0 2.6e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK20338.2 - 2.9e-09 36.7 0.2 5.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TRAPPC9-Trs120 PF08626.6 CBK20339.2 - 6.4e-17 60.2 1.3 1.1e-11 42.9 0.0 3.3 3 0 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GATase_2 PF00310.16 CBK20340.2 - 2.1e-23 82.6 0.0 5.4e-19 68.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBK20340.2 - 2.8e-14 53.1 0.0 7.2e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBK20340.2 - 1.5e-12 47.3 0.0 3.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CBK20340.2 - 1.1e-08 34.8 0.2 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CBK20340.2 - 1.8e-05 23.6 0.0 2.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA_27 PF13514.1 CBK20340.2 - 0.19 9.3 0.0 0.27 8.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.7 CBK20341.2 - 2.4e-40 138.7 18.8 9.3e-37 127.0 9.4 2.0 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein RD3 PF14473.1 CBK20341.2 - 0.081 12.4 4.9 0.16 11.4 3.4 1.4 1 0 0 1 1 1 0 RD3 protein TFIIF_alpha PF05793.7 CBK20341.2 - 0.16 10.2 13.7 0.19 10.0 9.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Antigen_Bd37 PF11641.3 CBK20341.2 - 0.57 9.4 5.9 0.85 8.8 4.1 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein PA26 PF04636.8 CBK20341.2 - 0.76 8.3 3.8 0.88 8.1 2.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.9 CBK20341.2 - 6.7 4.6 10.2 7.4 4.4 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SseC PF04888.7 CBK20341.2 - 7.2 5.8 6.3 10 5.3 4.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Vps39_2 PF10367.4 CBK20342.2 - 1e-21 77.1 0.6 3e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 CBK20342.2 - 0.0002 20.9 4.1 0.0002 20.9 0.3 2.4 3 0 0 3 3 3 1 Region in Clathrin and VPS CNH PF00780.17 CBK20343.2 - 1.7e-22 80.1 0.0 2.8e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain TPR_11 PF13414.1 CBK20343.2 - 0.028 14.0 0.1 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 CBK20343.2 - 0.15 11.7 0.7 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat He_PIG PF05345.7 CBK20344.2 - 3.5e-16 58.9 31.6 4.4e-05 23.4 0.1 5.6 5 1 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK20344.2 - 1.2e-05 25.0 7.6 1.7 8.5 0.1 4.5 4 0 0 4 4 4 3 Immunoglobulin I-set domain IncA PF04156.9 CBK20344.2 - 0.01 15.4 0.4 0.016 14.8 0.3 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK20344.2 - 0.012 15.5 13.7 1.2 9.2 0.1 5.0 5 0 0 5 5 5 0 Hormone receptor domain PIRT PF15099.1 CBK20344.2 - 0.019 14.1 0.0 0.06 12.5 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Mg_trans_NIPA PF05653.9 CBK20344.2 - 0.055 12.4 0.2 2.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium transporter NIPA DUF4097 PF13349.1 CBK20344.2 - 0.39 10.2 4.2 0.26 10.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) PKD PF00801.15 CBK20344.2 - 0.74 9.6 0.0 0.74 9.6 0.0 3.9 6 0 0 6 6 6 0 PKD domain hEGF PF12661.2 CBK20344.2 - 1.1 9.4 7.6 22 5.4 0.1 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF DUF3185 PF11381.3 CBK20344.2 - 6.1 6.6 10.4 17 5.2 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) DEAD_2 PF06733.10 CBK20345.2 - 3.4e-09 36.3 3.0 3.4e-09 36.3 2.1 1.7 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 CBK20345.2 - 1.8e-07 31.1 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK20345.2 - 0.00031 20.2 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CBK20345.2 - 0.0015 18.1 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK20345.2 - 0.045 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3128 PF11326.3 CBK20345.2 - 0.053 13.6 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) SNF2_N PF00176.18 CBK20345.2 - 0.11 11.2 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD_2 PF06733.10 CBK20346.2 - 2.9e-20 72.3 0.0 4.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 DUF483 PF04467.7 CBK20346.2 - 0.07 13.2 0.1 2.7 8.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF483) Helicase_C_2 PF13307.1 CBK20347.2 - 1.2e-36 126.1 0.0 1.7e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain PAD_porph PF04371.10 CBK20348.2 - 1.6e-134 448.0 0.0 1.9e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 CBK20348.2 - 0.044 12.8 0.0 12 4.8 0.0 3.0 3 0 0 3 3 3 0 Amidinotransferase DBP10CT PF08147.7 CBK20349.2 - 9.1e-15 54.2 4.1 2.3e-14 52.9 2.8 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DEAD PF00270.24 CBK20351.2 - 7.9e-29 100.3 0.0 5.4e-23 81.3 0.0 3.9 3 1 0 3 3 3 3 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK20351.2 - 3.7e-24 84.3 0.0 8.9e-24 83.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBK20351.2 - 0.008 14.6 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) SRPRB PF09439.5 CBK20352.2 - 6.7e-27 93.8 0.0 8.7e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBK20352.2 - 5.2e-09 35.5 0.0 7.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK20352.2 - 3.1e-06 26.4 0.0 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK20352.2 - 0.00012 22.5 0.0 0.00027 21.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CBK20352.2 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBK20352.2 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK20352.2 - 0.02 13.6 0.1 3.9 6.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 CBK20352.2 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIM PF00121.13 CBK20353.2 - 6e-84 280.9 0.2 6e-84 280.9 0.1 1.5 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_C PF02800.15 CBK20353.2 - 1.6e-69 232.3 0.0 5.9e-69 230.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBK20353.2 - 4.2e-56 189.1 0.1 1e-55 187.8 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.9 CBK20353.2 - 0.035 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family Rib_5-P_isom_A PF06026.9 CBK20354.2 - 2.5e-59 199.4 0.3 3e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CBK20354.2 - 0.0016 18.1 0.2 0.0049 16.5 0.0 1.8 2 0 0 2 2 2 1 DeoR C terminal sensor domain eIF3_N PF09440.5 CBK20356.2 - 1.5e-11 44.5 0.2 5.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain GHMP_kinases_C PF08544.8 CBK20357.2 - 1e-08 35.2 0.1 2.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 GHMP kinases C terminal CSTF2_hinge PF14327.1 CBK20357.2 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3215 PF11503.3 CBK20357.2 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) TYW3 PF02676.9 CBK20358.2 - 8.1e-57 191.6 0.0 9.2e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 He_PIG PF05345.7 CBK20360.2 - 4.1e-05 23.5 0.1 0.00014 21.8 0.1 1.9 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.15 CBK20360.2 - 0.094 13.0 3.7 0.55 10.6 0.2 2.8 2 0 0 2 2 2 0 Sushi domain (SCR repeat) P12 PF12669.2 CBK20360.2 - 0.29 11.3 2.2 0.66 10.2 1.5 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family LRR_8 PF13855.1 CBK20361.2 - 0.0011 18.7 3.3 0.047 13.4 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK20361.2 - 0.0023 17.5 2.5 0.0083 15.7 0.5 2.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) hSac2 PF12456.3 CBK20361.2 - 0.061 12.7 0.9 1.3 8.4 0.0 3.0 2 1 2 4 4 4 0 Inositol phosphatase LRR_6 PF13516.1 CBK20361.2 - 0.51 10.5 4.7 2.5 8.4 0.0 3.8 3 1 1 4 4 4 0 Leucine Rich repeat Actin PF00022.14 CBK20362.2 - 6.8e-146 485.7 0.0 7.7e-146 485.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK20362.2 - 0.0072 14.9 0.0 0.025 13.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Methyltransf_29 PF03141.11 CBK20362.2 - 0.042 12.1 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 CBK20362.2 - 0.1 13.0 0.0 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) POR_N PF01855.14 CBK20363.2 - 6.5e-72 241.7 0.5 2.6e-71 239.8 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.15 CBK20363.2 - 7.3e-43 146.5 0.0 1.2e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBK20363.2 - 2.8e-25 88.9 0.1 7e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin EKR PF10371.4 CBK20363.2 - 5.1e-21 73.9 0.2 4.4e-20 71.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function POR PF01558.13 CBK20363.2 - 4.7e-20 72.1 0.0 1.5e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.16 CBK20363.2 - 1.7e-08 35.0 0.0 6.5e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.1 CBK20363.2 - 3.5e-08 33.5 10.5 0.0011 19.1 1.3 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK20363.2 - 1e-07 32.1 9.9 1e-07 32.1 6.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK20363.2 - 1.7e-07 31.8 8.9 0.0036 18.0 1.2 3.0 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.16 CBK20363.2 - 2.2e-07 30.5 0.1 5.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK20363.2 - 1.6e-06 27.4 23.8 0.00015 21.1 3.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.1 CBK20363.2 - 2.4e-06 27.2 8.8 2.4e-06 27.2 6.1 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK20363.2 - 8.1e-06 25.7 0.2 2.9e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 Transketolase, C-terminal domain Fer4_8 PF13183.1 CBK20363.2 - 1.1e-05 25.4 7.9 3.7e-05 23.6 5.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 CBK20363.2 - 4.3e-05 23.7 7.1 0.017 15.4 1.5 3.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CBK20363.2 - 9.6e-05 22.1 14.2 0.001 18.9 9.9 2.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK20363.2 - 0.00025 20.7 7.0 0.00025 20.7 4.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBK20363.2 - 0.00034 20.9 5.9 0.086 13.2 0.2 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK20363.2 - 0.00045 19.9 18.1 0.0013 18.5 1.7 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Flavodoxin_5 PF12724.2 CBK20363.2 - 0.082 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain GSH-S_N PF02951.9 CBK20363.2 - 0.088 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Fer4_15 PF13459.1 CBK20363.2 - 2 9.0 11.5 3.4 8.3 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain GTP_EFTU PF00009.22 CBK20364.2 - 1.7e-56 190.6 0.0 2.3e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK20364.2 - 1e-33 115.4 0.1 3.1e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK20364.2 - 5.6e-10 39.1 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK20364.2 - 0.00011 22.1 0.1 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK20364.2 - 0.029 13.5 0.4 0.072 12.2 0.1 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK20364.2 - 0.04 14.4 0.4 0.61 10.5 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein Glyco_hydro_35 PF01301.14 CBK20365.2 - 1.7e-102 343.0 1.2 2.1e-102 342.7 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBK20365.2 - 2.7e-11 43.2 0.2 6.4e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 Beta-galactosidase ArfGap PF01412.13 CBK20366.2 - 5.7e-35 119.6 0.6 1.2e-34 118.6 0.4 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RGS PF00615.14 CBK20366.2 - 0.072 13.2 0.1 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain RRM_1 PF00076.17 CBK20367.2 - 2.7e-12 46.1 0.0 5.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20367.2 - 5.8e-08 32.6 0.0 9.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20367.2 - 5.8e-05 22.8 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2723 PF11028.3 CBK20368.2 - 4e-12 45.9 4.4 8.4e-12 44.9 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Actin PF00022.14 CBK20369.2 - 2.2e-147 490.5 0.0 2.9e-147 490.2 0.0 1.1 1 0 0 1 1 1 1 Actin AAA PF00004.24 CBK20369.2 - 1.5e-41 141.7 0.0 4e-41 140.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBK20369.2 - 7.8e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBK20369.2 - 5.1e-05 23.4 0.2 0.0097 16.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBK20369.2 - 7.6e-05 22.2 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBK20369.2 - 0.00024 21.1 0.4 0.0011 18.9 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CBK20369.2 - 0.00036 20.2 0.1 0.004 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBK20369.2 - 0.0042 16.9 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBK20369.2 - 0.0048 17.7 0.1 0.013 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBK20369.2 - 0.008 16.2 0.0 0.025 14.6 0.0 1.8 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 CBK20369.2 - 0.0082 16.4 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK20369.2 - 0.0088 15.7 0.0 0.03 14.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CBK20369.2 - 0.022 13.4 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CBK20369.2 - 0.038 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBK20369.2 - 0.044 13.1 0.1 0.16 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBK20369.2 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CBK20369.2 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.24 CBK20369.2 - 0.17 11.4 0.1 7.3 6.0 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 CBK20369.2 - 0.26 10.3 0.0 0.66 9.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.27 CBK20370.2 - 0.011 15.5 0.1 15 5.6 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat MFS_1 PF07690.11 CBK20371.2 - 1e-26 93.5 41.7 2.1e-26 92.5 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CBK20371.2 - 0.003 17.5 1.9 0.0078 16.2 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) YajC PF02699.10 CBK20371.2 - 0.028 14.0 0.2 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit MORN PF02493.15 CBK20372.2 - 0.00097 18.7 21.4 0.058 13.1 0.0 5.6 6 0 0 6 6 6 3 MORN repeat Orn_Arg_deC_N PF02784.11 CBK20373.2 - 1.3e-46 158.8 0.0 1.7e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBK20373.2 - 2.7e-12 46.4 0.0 5.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Pkinase PF00069.20 CBK20374.2 - 1.2e-31 109.8 0.4 7.8e-27 94.0 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20374.2 - 4.3e-19 68.6 0.1 9e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TP53IP5 PF15331.1 CBK20374.2 - 2.3 8.0 6.5 4 7.2 4.5 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Daxx PF03344.10 CBK20374.2 - 4.8 5.5 18.6 6.4 5.1 12.9 1.1 1 0 0 1 1 1 0 Daxx Family MCM PF00493.18 CBK20375.2 - 1.4e-118 395.4 0.0 1.9e-118 395.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CBK20375.2 - 1.8e-07 30.9 0.0 5.2e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBK20375.2 - 4.3e-07 29.2 0.3 0.0023 17.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBK20375.2 - 0.00056 19.4 0.1 0.0022 17.5 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBK20375.2 - 0.01 15.4 0.1 0.13 11.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cadherin PF00028.12 CBK20376.2 - 1.4e-80 265.6 17.4 4.7e-11 42.7 0.4 14.2 14 0 0 14 14 14 12 Cadherin domain TIG PF01833.19 CBK20376.2 - 5e-52 173.8 65.7 2.6e-11 43.3 0.9 14.5 13 0 0 13 13 13 11 IPT/TIG domain PKD PF00801.15 CBK20376.2 - 0.26 11.0 5.6 38 4.1 0.0 5.2 5 0 0 5 5 5 0 PKD domain Phage_lysis PF03245.8 CBK20376.2 - 5 7.1 3.9 8.6 6.3 2.7 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Cadherin PF00028.12 CBK20377.2 - 8.6e-09 35.5 0.2 2.8e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 Cadherin domain DUF462 PF04315.7 CBK20378.2 - 5.9e-19 68.0 0.1 60 2.9 0.0 23.9 31 0 0 31 31 31 2 Protein of unknown function, DUF462 Helitron_like_N PF14214.1 CBK20379.2 - 0.038 13.7 0.5 0.057 13.1 0.3 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Pox_P4B PF03292.9 CBK20379.2 - 0.5 8.2 2.4 0.63 7.9 1.7 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein zf-BED PF02892.10 CBK20379.2 - 2.9 7.7 6.6 3.5 7.4 1.0 2.4 1 1 1 2 2 2 0 BED zinc finger Miro PF08477.8 CBK20380.2 - 0.0035 17.8 0.1 0.019 15.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Ctr PF04145.10 CBK20380.2 - 0.21 11.6 0.3 0.44 10.6 0.2 1.6 1 0 0 1 1 1 0 Ctr copper transporter family SNARE PF05739.14 CBK20382.2 - 2.8e-09 36.5 3.8 3.4e-09 36.2 2.6 1.1 1 0 0 1 1 1 1 SNARE domain PgaD PF13994.1 CBK20382.2 - 0.012 15.1 0.1 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Dispanin PF04505.7 CBK20382.2 - 0.014 14.9 0.6 0.017 14.6 0.4 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF4366 PF14283.1 CBK20382.2 - 0.014 14.7 0.1 0.016 14.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Rifin_STEVOR PF02009.11 CBK20382.2 - 0.025 14.2 2.3 0.028 14.0 1.6 1.1 1 0 0 1 1 1 0 Rifin/stevor family Neurensin PF14927.1 CBK20382.2 - 0.029 13.7 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Neurensin Synaptobrevin PF00957.16 CBK20382.2 - 0.029 13.9 3.3 0.038 13.5 2.3 1.2 1 0 0 1 1 1 0 Synaptobrevin Fusion_gly PF00523.13 CBK20382.2 - 0.03 12.3 0.7 0.031 12.3 0.5 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF3753 PF12575.3 CBK20382.2 - 0.032 14.0 1.3 0.036 13.8 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Epiglycanin_C PF14654.1 CBK20382.2 - 0.034 14.1 0.2 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2562 PF10814.3 CBK20382.2 - 0.037 13.9 0.8 0.038 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) LRRC37AB_C PF14914.1 CBK20382.2 - 0.053 12.9 0.9 0.057 12.8 0.6 1.0 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Herpes_US9 PF06072.6 CBK20382.2 - 0.055 13.3 0.3 0.069 12.9 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MEDS PF14417.1 CBK20382.2 - 0.079 12.0 0.1 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PAS_7 PF12860.2 CBK20382.2 - 0.091 12.7 0.2 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 PAS fold Nup54 PF13874.1 CBK20382.2 - 0.1 12.2 0.6 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF805 PF05656.9 CBK20382.2 - 0.13 12.1 0.1 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) TOM20_plant PF06552.7 CBK20382.2 - 0.13 11.8 0.4 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DUF912 PF06024.7 CBK20382.2 - 0.14 12.2 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3708 PF12501.3 CBK20382.2 - 0.18 11.6 0.8 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter CENP-H PF05837.7 CBK20382.2 - 0.29 11.3 2.7 0.35 11.0 0.9 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) NapE PF06796.6 CBK20382.2 - 1.3 8.3 6.8 3.2 7.1 4.7 1.8 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE LRR_8 PF13855.1 CBK20384.2 - 0.0079 15.9 5.3 0.83 9.4 0.2 3.1 2 1 1 3 3 3 2 Leucine rich repeat Trypan_PARP PF05887.6 CBK20384.2 - 0.027 14.2 9.4 0.04 13.7 6.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.8 CBK20384.2 - 2.4 6.7 14.9 3.3 6.2 10.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PLRV_ORF5 PF01690.12 CBK20384.2 - 8.7 5.3 32.7 0.67 9.0 11.2 2.2 1 1 1 2 2 2 0 Potato leaf roll virus readthrough protein DUF1888 PF08985.6 CBK20386.2 - 0.011 15.3 0.0 2.7 7.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1888) SpoU_methylase PF00588.14 CBK20387.2 - 1.4e-25 89.7 0.0 2.4e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-C2H2 PF00096.21 CBK20388.2 - 2.3e-16 59.0 54.8 0.00034 20.7 0.2 8.1 7 1 1 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBK20388.2 - 1.2e-14 53.7 53.5 1.1e-05 25.4 0.7 8.0 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBK20388.2 - 1.8e-13 49.7 52.1 0.0034 17.6 1.1 8.1 7 1 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.2 CBK20388.2 - 0.00054 20.0 36.3 0.064 13.4 1.4 8.2 8 0 0 8 8 8 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CBK20388.2 - 0.0052 16.9 3.0 0.0052 16.9 2.1 7.5 9 1 0 9 9 9 2 C2H2-type zinc-finger domain zf-met2 PF12907.2 CBK20388.2 - 0.012 15.5 0.1 0.012 15.5 0.1 4.4 4 1 1 5 5 5 0 Zinc-binding ALAD PF00490.16 CBK20388.2 - 0.33 9.7 1.5 0.83 8.4 0.7 1.7 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase zf-RAG1 PF10426.4 CBK20388.2 - 0.4 10.6 0.0 0.4 10.6 0.0 4.1 6 0 0 6 6 6 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_jaz PF12171.3 CBK20388.2 - 4 7.7 41.0 0.24 11.5 0.7 6.6 7 1 1 8 8 8 0 Zinc-finger double-stranded RNA-binding DUF3510 PF12022.3 CBK20389.2 - 1.6e-07 31.4 0.1 2.4e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Ribosomal_L6e PF01159.14 CBK20390.2 - 3.3e-22 78.7 0.2 4.4e-21 75.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e Myb_DNA-binding PF00249.26 CBK20391.2 - 2.8e-41 139.3 16.9 1.4e-12 47.4 0.4 5.5 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK20391.2 - 2.2e-37 126.9 14.8 2.1e-14 53.3 0.4 6.0 1 1 4 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CBK20391.2 - 0.00089 19.0 3.4 0.21 11.4 0.7 4.1 3 1 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.3 CBK20391.2 - 0.016 15.0 5.2 0.19 11.6 0.3 3.8 3 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CBK20391.2 - 0.28 11.3 20.8 0.44 10.7 0.1 5.3 5 1 1 6 6 6 0 Myb/SANT-like DNA-binding domain eIF-4B PF06273.6 CBK20391.2 - 2.2 6.9 4.2 1.7 7.3 0.1 2.1 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B DUF4366 PF14283.1 CBK20392.2 - 0.0038 16.6 0.4 0.0043 16.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Rsd_AlgQ PF04353.8 CBK20392.2 - 0.0069 16.0 0.0 0.0085 15.8 0.0 1.1 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CYSTM PF12734.2 CBK20392.2 - 0.067 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF4131 PF13567.1 CBK20392.2 - 0.13 11.6 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fcf1 PF04900.7 CBK20393.2 - 1.1e-40 137.8 0.8 1.1e-40 137.8 0.6 1.9 2 0 0 2 2 2 1 Fcf1 Cpn60_TCP1 PF00118.19 CBK20394.2 - 2.6e-148 494.6 0.1 3.1e-148 494.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PHO4 PF01384.15 CBK20396.2 - 1.7e-99 332.5 19.8 2.1e-97 325.6 13.7 2.8 1 1 0 1 1 1 1 Phosphate transporter family FAM176 PF14851.1 CBK20396.2 - 0.019 14.6 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 FAM176 family Tmemb_9 PF05434.6 CBK20396.2 - 0.067 12.9 0.1 3 7.5 0.0 2.3 2 0 0 2 2 2 0 TMEM9 HTH_IclR PF09339.5 CBK20396.2 - 0.12 12.0 0.1 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF1049 PF06305.6 CBK20396.2 - 0.13 11.7 0.0 0.13 11.7 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1049) IncA PF04156.9 CBK20396.2 - 0.77 9.3 0.0 0.77 9.3 0.0 3.1 4 0 0 4 4 4 0 IncA protein tRNA-synt_1g PF09334.6 CBK20397.2 - 5e-140 466.6 0.0 8e-140 465.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBK20397.2 - 1.4e-09 36.5 0.4 0.00026 19.1 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) zf-ribbon_3 PF13248.1 CBK20397.2 - 0.015 14.5 4.2 2.2 7.6 1.6 3.2 2 0 0 2 2 2 0 zinc-ribbon domain GST_C PF00043.20 CBK20397.2 - 0.017 15.0 0.0 0.095 12.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PDDEXK_1 PF12705.2 CBK20397.2 - 0.035 13.4 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DZR PF12773.2 CBK20397.2 - 0.082 12.7 8.1 0.7 9.7 5.6 2.6 1 1 0 1 1 1 0 Double zinc ribbon GST_C_2 PF13410.1 CBK20397.2 - 0.38 10.6 1.8 0.6 10.0 0.0 2.2 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain zf-RING_3 PF14369.1 CBK20397.2 - 1 9.4 5.7 0.14 12.1 0.8 2.0 2 0 0 2 2 2 0 zinc-finger Cnd3 PF12719.2 CBK20398.2 - 7.3e-17 61.2 4.3 3.3e-15 55.8 0.6 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CBK20398.2 - 0.00056 19.7 0.9 17 5.8 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat LRR_8 PF13855.1 CBK20399.2 - 0.00024 20.7 1.8 0.081 12.6 0.1 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK20399.2 - 0.0074 15.8 0.9 1.5 8.5 0.1 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) hSac2 PF12456.3 CBK20399.2 - 0.033 13.5 1.0 2 7.8 0.0 3.0 1 1 2 3 3 3 0 Inositol phosphatase Mtc PF03820.12 CBK20400.2 - 0.17 10.5 0.6 0.22 10.1 0.4 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier DnaJ PF00226.26 CBK20402.2 - 2.1e-15 56.2 0.1 1e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 CBK20402.2 - 3.3e-13 49.0 1.1 1.9e-06 27.3 0.0 3.8 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 CBK20402.2 - 8.1e-10 37.8 0.6 0.04 13.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK20402.2 - 1.2e-09 37.2 4.4 0.025 14.3 0.0 5.7 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20402.2 - 8.7e-08 31.5 0.0 1.5 8.9 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK20402.2 - 4.2e-07 29.7 0.0 0.00078 19.2 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK20402.2 - 4.4e-07 29.5 0.6 0.32 11.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK20402.2 - 1.3e-06 28.6 0.0 0.025 14.8 0.0 3.6 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20402.2 - 1.9e-05 25.1 0.0 0.0094 16.6 0.0 3.4 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20402.2 - 8.9e-05 22.7 0.0 3.6 8.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20402.2 - 9.2e-05 22.3 0.0 0.1 12.5 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK20402.2 - 0.0018 18.3 0.0 4.1 7.5 0.0 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBK20402.2 - 0.0097 16.3 0.1 2.4 8.8 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBK20402.2 - 0.049 12.6 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribophorin_I PF04597.9 CBK20403.2 - 7.1e-99 331.2 1.9 8.2e-99 331.0 1.3 1.0 1 0 0 1 1 1 1 Ribophorin I YscJ_FliF PF01514.12 CBK20403.2 - 0.082 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family DEAD PF00270.24 CBK20404.2 - 1.1e-14 54.3 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK20404.2 - 2.4e-06 27.4 0.0 6.5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBK20404.2 - 0.008 16.3 0.1 0.1 12.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain Ribosomal_L14 PF00238.14 CBK20405.2 - 9.1e-35 119.0 0.0 1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_1 PF00133.17 CBK20407.2 - 7.5e-34 116.6 0.0 3.1e-22 78.3 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBK20407.2 - 5.8e-24 84.4 1.0 6.8e-12 44.7 0.0 3.9 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBK20407.2 - 2.7e-10 40.2 0.1 1e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CBK20407.2 - 6.3e-10 38.6 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 CBK20407.2 - 0.011 14.4 0.0 0.021 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) YchF-GTPase_C PF06071.8 CBK20407.2 - 0.076 12.8 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF933) CIA30 PF08547.7 CBK20408.2 - 4.4e-20 72.1 0.0 5.4e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Med6 PF04934.9 CBK20409.2 - 6.4e-17 61.4 3.2 9.8e-12 44.6 0.3 2.5 1 1 1 2 2 2 2 MED6 mediator sub complex component Pox_int_trans PF05718.7 CBK20410.2 - 0.029 12.9 0.8 0.14 10.6 0.1 1.8 1 1 1 2 2 2 0 Poxvirus intermediate transcription factor CPW_WPC PF09717.5 CBK20410.2 - 0.091 13.4 2.3 0.16 12.6 1.6 1.4 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Cytochrom_C1 PF02167.10 CBK20410.2 - 0.095 12.3 0.2 0.13 11.8 0.2 1.3 1 1 0 1 1 1 0 Cytochrome C1 family PolC_DP2 PF03833.8 CBK20410.2 - 0.11 10.1 0.6 0.12 10.0 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FERM_M PF00373.13 CBK20410.2 - 0.22 11.7 1.6 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 FERM central domain Tom22 PF04281.8 CBK20413.2 - 2.9e-07 30.1 0.2 3.7e-06 26.5 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial import receptor subunit Tom22 Pkinase PF00069.20 CBK20414.2 - 1e-61 208.3 0.0 1.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20414.2 - 6.2e-33 113.9 0.0 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20414.2 - 1.2e-09 37.6 0.0 1.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK20414.2 - 0.0027 17.4 0.0 0.29 10.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family FANCI_HD1 PF14679.1 CBK20414.2 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 FANCI helical domain 1 EF-hand_7 PF13499.1 CBK20415.2 - 1.1e-09 38.3 9.4 7.9e-05 22.7 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBK20415.2 - 1.3e-09 37.5 6.0 0.0033 16.9 0.5 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBK20415.2 - 2.8e-09 36.0 9.6 3.4e-05 23.3 0.3 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBK20415.2 - 2e-07 29.8 13.4 0.0001 21.3 0.7 3.9 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 CBK20415.2 - 1.2e-06 27.6 0.7 0.003 16.8 0.1 3.5 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 CBK20415.2 - 1e-05 25.3 0.4 0.00032 20.5 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CBK20415.2 - 0.0006 19.8 1.6 0.21 11.5 0.0 2.7 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dehydratase_SU PF02287.10 CBK20415.2 - 0.11 12.2 0.1 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Dehydratase small subunit Sec23_helical PF04815.10 CBK20415.2 - 0.13 11.7 2.1 0.56 9.6 0.1 2.6 2 1 1 3 3 3 0 Sec23/Sec24 helical domain FRG1 PF06229.7 CBK20415.2 - 0.13 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 FRG1-like family Gp_dh_N PF00044.19 CBK20416.2 - 7.9e-33 113.5 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 CBK20416.2 - 4.2e-28 97.7 0.0 5.9e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DapB_N PF01113.15 CBK20416.2 - 0.012 15.4 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 CBK20416.2 - 0.017 14.6 0.0 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 CBK20416.2 - 0.07 13.5 0.0 7.2 7.1 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent COPI_assoc PF08507.5 CBK20417.2 - 3.9e-15 55.7 12.1 5.3e-15 55.3 8.4 1.2 1 0 0 1 1 1 1 COPI associated protein PRA1 PF03208.14 CBK20417.2 - 0.007 15.7 4.8 0.014 14.7 3.0 1.7 1 1 0 1 1 1 1 PRA1 family protein SLAC1 PF03595.12 CBK20417.2 - 0.011 14.4 7.3 0.014 14.0 5.1 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF1206 PF06724.6 CBK20417.2 - 0.35 10.6 2.8 7.5 6.3 0.0 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF872 PF05915.7 CBK20417.2 - 7.4 6.4 13.0 0.9 9.4 2.6 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Cytochrom_B561 PF03188.11 CBK20417.2 - 7.6 6.3 9.1 10 5.9 4.3 2.3 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 MBOAT PF03062.14 CBK20418.2 - 2.8e-24 85.8 18.4 3.6e-24 85.4 12.8 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CBK20418.2 - 3.8e-06 26.8 3.0 3.8e-06 26.8 2.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family EF-hand_7 PF13499.1 CBK20420.2 - 4.4e-13 49.1 0.5 1.1e-12 47.9 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair Na_Ca_ex PF01699.19 CBK20420.2 - 7.7e-13 48.2 8.4 1.3e-12 47.4 5.8 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein EF-hand_1 PF00036.27 CBK20420.2 - 2.7e-09 35.6 0.9 0.00049 19.2 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBK20420.2 - 1.7e-08 33.9 1.7 3e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBK20420.2 - 2.3e-08 33.2 3.2 0.00074 19.1 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBK20420.2 - 0.0014 17.8 0.2 0.12 11.7 0.0 2.5 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 CBK20420.2 - 0.02 14.9 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SAP PF02037.22 CBK20420.2 - 0.023 14.2 0.1 0.81 9.2 0.0 2.5 2 0 0 2 2 2 0 SAP domain DUF3522 PF12036.3 CBK20420.2 - 0.027 14.2 4.8 0.053 13.3 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF3816 PF12822.2 CBK20420.2 - 0.36 10.7 9.2 0.69 9.7 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) RRP7 PF12923.2 CBK20421.2 - 2.1e-07 31.0 2.6 3.3e-07 30.3 1.8 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CBK20421.2 - 0.00031 20.2 0.1 0.004 16.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20421.2 - 0.0059 16.5 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COX16 PF14138.1 CBK20421.2 - 6.3 7.0 6.0 2.4 8.4 0.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 BRCT PF00533.21 CBK20422.2 - 7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBK20422.2 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 twin BRCT domain SSPI PF14098.1 CBK20422.2 - 0.25 11.2 2.1 0.57 10.1 1.3 1.7 2 0 0 2 2 2 0 Small, acid-soluble spore protein I GILT PF03227.11 CBK20423.2 - 1.1e-25 89.5 1.3 1.6e-25 89.0 0.9 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF1604 PF07713.8 CBK20424.2 - 3.7e-28 97.1 1.9 4.1e-28 97.0 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) Toxin_3 PF00537.13 CBK20425.2 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain Notch PF00066.12 CBK20426.2 - 5.4e-15 55.3 29.2 2.1e-07 31.1 7.4 2.4 2 0 0 2 2 2 2 LNR domain DUF3184 PF11380.3 CBK20426.2 - 2.7e-07 28.9 0.2 0.00074 17.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF167 PF02594.11 CBK20427.2 - 2.7e-21 75.2 0.1 3.9e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Exo_endo_phos PF03372.18 CBK20428.2 - 6.3e-17 62.3 0.0 8.4e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cullin PF00888.17 CBK20429.2 - 0.00014 20.5 3.6 0.00016 20.4 2.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBK20430.2 - 2e-09 37.1 1.4 3.7e-09 36.2 0.4 1.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.17 CBK20430.2 - 1.1e-08 34.1 1.1 2.6e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Cullin family FolB PF02152.13 CBK20430.2 - 0.047 13.8 0.2 0.076 13.1 0.1 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase Yip1 PF04893.12 CBK20431.2 - 3 7.3 10.7 1.2 8.6 5.4 1.6 2 0 0 2 2 2 0 Yip1 domain GILT PF03227.11 CBK20432.2 - 1.1e-16 60.6 1.4 1.7e-16 60.0 0.9 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) ubiquitin PF00240.18 CBK20433.2 - 1.8e-35 120.1 0.7 1.9e-35 120.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK20433.2 - 1.4e-20 72.7 0.7 1.6e-20 72.5 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBK20433.2 - 1.1e-06 28.7 0.1 4.5e-06 26.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBK20433.2 - 4.9e-05 23.0 0.0 5.4e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBK20433.2 - 0.003 17.4 0.1 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK20433.2 - 0.0054 16.8 0.0 0.0065 16.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBK20433.2 - 0.061 13.3 0.0 0.18 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Fucokinase PF07959.7 CBK20434.2 - 2.4e-30 105.4 0.0 3.4e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.8 CBK20434.2 - 1.5e-07 31.5 0.0 4.2e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBK20434.2 - 7.2e-06 25.9 0.3 7.2e-06 25.9 0.2 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain Corona_NS2A PF05213.7 CBK20434.2 - 0.24 10.6 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein LSM PF01423.17 CBK20435.2 - 9.1e-15 53.9 0.1 1.1e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 CBK20436.2 - 3.2e-57 193.6 0.0 3.2e-57 193.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20436.2 - 6.9e-23 81.0 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK20436.2 - 0.059 12.4 0.2 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK20436.2 - 0.19 11.4 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SBP_bac_3 PF00497.15 CBK20437.2 - 2.8e-07 29.9 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NIF PF03031.13 CBK20438.2 - 2.7e-49 166.8 0.2 3.4e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cofilin_ADF PF00241.15 CBK20439.2 - 1.2e-21 76.9 0.1 1.2e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NDUF_B7 PF05676.8 CBK20441.2 - 7.5e-21 73.3 2.2 7.9e-21 73.2 1.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 CBK20441.2 - 0.0081 15.9 1.3 0.01 15.6 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Chordopox_G3 PF06129.7 CBK20442.2 - 0.011 15.8 0.8 0.012 15.6 0.5 1.1 1 0 0 1 1 1 0 Chordopoxvirus G3 protein DUF3278 PF11683.3 CBK20442.2 - 0.051 13.5 0.1 0.053 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Transket_pyr PF02779.19 CBK20444.2 - 6.5e-47 159.3 0.0 9e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBK20444.2 - 1.4e-42 144.5 0.1 3.3e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Na_H_Exchanger PF00999.16 CBK20445.2 - 4e-13 48.6 19.8 5.2e-13 48.2 13.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AgrB PF04647.10 CBK20445.2 - 3.1 6.8 12.4 0.018 14.1 0.9 2.5 3 0 0 3 3 3 0 Accessory gene regulator B Trypan_PARP PF05887.6 CBK20447.2 - 0.042 13.6 7.9 0.061 13.1 5.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) hSac2 PF12456.3 CBK20447.2 - 0.07 12.5 0.3 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Inositol phosphatase LRR_8 PF13855.1 CBK20447.2 - 0.35 10.6 5.1 18 5.1 1.0 3.1 2 1 1 3 3 3 0 Leucine rich repeat Sialidase PF02973.11 CBK20447.2 - 0.39 9.6 3.5 5.4 5.9 0.1 3.0 2 1 1 3 3 3 0 Sialidase, N-terminal domain DEC-1_N PF04625.8 CBK20447.2 - 9 4.8 13.8 13 4.3 9.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Beach PF02138.13 CBK20448.2 - 1e-78 264.5 0.0 1.3e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CBK20448.2 - 4e-11 42.7 0.0 7.9e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH Ras PF00071.17 CBK20449.2 - 7.4e-66 220.5 1.1 8.7e-66 220.2 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK20449.2 - 2.8e-20 72.9 0.1 5e-20 72.1 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBK20449.2 - 1.2e-17 63.7 0.3 1.4e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK20449.2 - 7.9e-08 31.7 0.2 9.3e-08 31.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK20449.2 - 0.0001 22.2 0.1 0.0003 20.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK20449.2 - 0.00012 21.5 0.4 0.00022 20.7 0.2 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBK20449.2 - 0.0007 19.7 0.0 0.0025 17.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 CBK20449.2 - 0.0012 19.0 0.1 0.064 13.4 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 CBK20449.2 - 0.0019 17.4 0.1 0.0024 17.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CBK20449.2 - 0.0034 16.5 0.0 0.016 14.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CBK20449.2 - 0.004 16.4 0.1 0.023 14.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 CBK20449.2 - 0.0069 16.3 0.0 0.061 13.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Ank PF00023.25 CBK20449.2 - 0.033 13.9 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat AAA_29 PF13555.1 CBK20449.2 - 0.04 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CBK20449.2 - 0.055 13.3 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBK20449.2 - 0.12 12.1 0.1 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CBK20449.2 - 0.31 9.6 4.7 2.6 6.6 0.6 2.7 1 1 1 2 2 2 0 G-protein alpha subunit UPRTase PF14681.1 CBK20450.2 - 6e-60 201.9 0.0 6.8e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBK20450.2 - 9.8e-07 28.5 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.20 CBK20451.2 - 2.3e-61 207.2 0.4 2.6e-61 207.0 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20451.2 - 9.3e-26 90.4 0.4 1.2e-25 90.1 0.3 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20451.2 - 0.00099 18.1 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBK20451.2 - 0.01 15.1 0.4 0.018 14.4 0.3 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CBK20451.2 - 0.087 11.8 0.1 0.18 10.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn10 PF00166.16 CBK20452.2 - 7.6e-23 80.2 0.0 1e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SoxG PF04268.7 CBK20452.2 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family MBF1 PF08523.5 CBK20453.2 - 3.1e-14 52.7 1.5 6.2e-14 51.7 1.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CBK20453.2 - 2.4e-13 49.6 0.2 3.7e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CBK20453.2 - 1.3e-07 31.6 0.0 3.1e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 CBK20453.2 - 2.1e-07 30.8 0.1 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 CBK20453.2 - 0.00012 21.6 0.1 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 CBK20453.2 - 0.041 13.6 0.2 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain FSA_C PF10479.4 CBK20453.2 - 0.044 11.8 0.1 0.045 11.8 0.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HTH_26 PF13443.1 CBK20453.2 - 0.14 12.3 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Pox_vIL-18BP PF05566.7 CBK20454.2 - 0.11 12.4 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein FpoO PF10621.4 CBK20455.2 - 0.06 13.4 2.4 0.082 12.9 1.7 1.2 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF3795 PF12675.2 CBK20455.2 - 0.17 12.1 3.5 0.25 11.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) DUF2769 PF10967.3 CBK20455.2 - 0.54 10.5 6.4 1.3 9.4 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) ADK_lid PF05191.9 CBK20455.2 - 0.99 9.1 8.8 0.4 10.3 0.4 2.6 3 1 0 3 3 3 0 Adenylate kinase, active site lid DZR PF12773.2 CBK20455.2 - 3.9 7.3 6.4 24 4.8 4.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon Pup PF05639.6 CBK20457.2 - 3.1 8.3 7.5 0.35 11.3 1.0 2.2 2 1 0 2 2 2 0 Pup-like protein HEAT_2 PF13646.1 CBK20458.2 - 0.031 14.5 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 HEAT repeats PUL PF08324.6 CBK20458.2 - 0.094 11.5 0.7 0.18 10.5 0.3 1.5 1 1 1 2 2 2 0 PUL domain Lactamase_B PF00753.22 CBK20459.2 - 3.7e-19 69.1 0.0 5.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBK20459.2 - 8.5e-06 25.4 0.0 1.2e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_S6e PF01092.14 CBK20460.2 - 9.8e-59 196.5 0.3 1.7e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e MutS_III PF05192.13 CBK20461.2 - 4e-24 85.5 2.0 4.5e-24 85.3 0.4 1.7 2 0 0 2 2 2 1 MutS domain III RAG1 PF12940.2 CBK20461.2 - 0.058 11.7 0.3 0.13 10.5 0.0 1.7 2 0 0 2 2 2 0 Recombination-activation protein 1 (RAG1) MutS_V PF00488.16 CBK20462.2 - 6.5e-37 127.1 0.0 9.9e-37 126.5 0.0 1.3 1 1 0 1 1 1 1 MutS domain V AAA_33 PF13671.1 CBK20462.2 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nitroreductase PF00881.19 CBK20463.2 - 3.3e-24 85.5 0.0 4.6e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Pro_isomerase PF00160.16 CBK20464.2 - 6.3e-44 149.8 0.1 7.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2_C PF14360.1 CBK20465.2 - 9.1e-10 38.6 8.2 4.7e-08 33.1 5.7 2.7 1 1 0 1 1 1 1 PAP2 superfamily C-terminal NicO PF03824.11 CBK20465.2 - 0.0053 16.1 1.0 0.009 15.3 0.7 1.4 1 0 0 1 1 1 1 High-affinity nickel-transport protein Cad PF03596.8 CBK20465.2 - 0.0078 15.9 2.1 0.013 15.2 1.1 1.5 1 1 0 1 1 1 1 Cadmium resistance transporter RRM_2 PF04059.7 CBK20466.2 - 2.4e-29 101.1 0.5 4.1e-29 100.4 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 Cnd2 PF05786.9 CBK20467.2 - 8.7e-36 123.7 0.5 1e-35 123.4 0.4 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Pkinase PF00069.20 CBK20469.2 - 4.8e-08 32.4 0.0 1.1e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20469.2 - 7e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase INCENP_ARK-bind PF03941.10 CBK20470.2 - 0.00038 20.2 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.22 CBK20470.2 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain Epimerase PF01370.16 CBK20471.2 - 2.4e-65 220.2 0.0 3.3e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBK20471.2 - 2.4e-06 26.6 0.0 6.7e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBK20471.2 - 0.0041 16.0 0.0 0.0082 15.0 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBK20471.2 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 CBK20471.2 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 CBK20471.2 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 CBK20471.2 - 0.089 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family zf-TRAF PF02176.13 CBK20472.2 - 0.0068 16.7 9.2 0.012 15.9 5.0 2.3 2 0 0 2 2 2 1 TRAF-type zinc finger Peptidase_S46 PF10459.4 CBK20472.2 - 0.073 11.4 9.7 0.092 11.1 6.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Asp-B-Hydro_N PF05279.6 CBK20472.2 - 0.58 9.9 13.7 0.76 9.5 9.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMPIT PF07851.8 CBK20472.2 - 3.4 6.6 9.5 5.1 6.0 6.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein PFK PF00365.15 CBK20473.2 - 8.5e-26 90.5 0.2 1.5e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Phosphofructokinase DUF2186 PF09952.4 CBK20473.2 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) UQ_con PF00179.21 CBK20474.2 - 1.9e-32 111.5 1.4 4.3e-31 107.2 1.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme ATP_transf PF09830.4 CBK20475.2 - 1.4e-17 63.2 0.0 1.5e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 ATP adenylyltransferase NUDIX PF00293.23 CBK20476.2 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Myosin_HC-like PF07058.6 CBK20476.2 - 0.12 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like DnaJ PF00226.26 CBK20477.2 - 6.4e-31 105.8 3.7 1.1e-30 105.1 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBK20477.2 - 2.1e-25 88.4 0.2 3.9e-22 77.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain Aa_trans PF01490.13 CBK20478.2 - 2.6e-38 131.5 32.3 2.9e-38 131.4 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Copine PF07002.11 CBK20479.2 - 3.9e-16 59.0 0.0 5.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Copine DHHA2 PF02833.9 CBK20480.2 - 0.048 13.8 0.1 0.055 13.6 0.1 1.1 1 0 0 1 1 1 0 DHHA2 domain PSP1 PF04468.7 CBK20481.2 - 4.5e-26 90.6 1.3 9.4e-26 89.6 0.9 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Mito_carr PF00153.22 CBK20482.2 - 1.1e-51 172.5 3.8 9.3e-22 76.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 CBK20483.2 - 0.00021 21.5 0.0 0.00023 21.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBK20483.2 - 0.0017 18.8 0.3 0.32 11.5 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK20483.2 - 0.0055 16.8 0.0 0.28 11.5 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 CBK20483.2 - 0.066 13.0 0.6 0.21 11.4 0.3 2.0 2 2 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 CBK20483.2 - 0.12 12.6 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Ankyrin repeats (many copies) FoP_duplication PF13865.1 CBK20486.2 - 3.4e-06 27.4 17.8 3.9e-05 24.0 12.3 2.5 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 EspB PF05802.6 CBK20486.2 - 0.056 12.3 0.5 0.065 12.1 0.3 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein SseC PF04888.7 CBK20486.2 - 0.23 10.7 1.2 0.26 10.5 0.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Mnd1 PF03962.10 CBK20486.2 - 0.72 9.4 4.7 0.92 9.1 3.2 1.1 1 0 0 1 1 1 0 Mnd1 family Thioredoxin PF00085.15 CBK20487.2 - 0.0081 15.8 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin FliJ PF02050.11 CBK20488.2 - 0.0073 16.3 47.6 0.021 14.8 8.9 3.3 1 1 2 3 3 3 2 Flagellar FliJ protein YlqD PF11068.3 CBK20488.2 - 0.0089 16.0 11.2 0.0089 16.0 7.7 3.7 1 1 4 5 5 5 1 YlqD protein TMF_DNA_bd PF12329.3 CBK20488.2 - 0.018 14.8 51.9 0.8 9.5 1.4 5.4 2 2 2 5 5 4 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 CBK20488.2 - 0.027 14.2 52.2 0.081 12.6 16.5 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 CBK20488.2 - 0.028 11.7 41.4 0.038 11.3 28.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 CBK20488.2 - 0.044 13.6 53.0 0.44 10.3 18.3 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CBK20488.2 - 0.064 12.4 49.4 0.73 9.0 16.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 CBK20488.2 - 0.065 11.6 37.4 0.086 11.2 25.1 1.7 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 CBK20488.2 - 0.092 11.9 11.2 0.21 10.7 1.0 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CBK20488.2 - 0.14 10.8 39.5 0.98 8.0 12.3 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.1 CBK20488.2 - 0.29 11.1 52.2 1.3 8.9 11.9 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) WEMBL PF05701.6 CBK20488.2 - 0.39 9.1 46.0 6.3 5.1 30.9 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light ATG16 PF08614.6 CBK20488.2 - 0.78 9.5 44.8 3.3 7.4 8.8 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Sec8_exocyst PF04048.9 CBK20488.2 - 0.78 9.3 28.8 0.25 10.9 2.8 3.7 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Prefoldin_2 PF01920.15 CBK20488.2 - 1.1 9.0 49.0 0.073 12.8 7.5 5.2 1 1 3 5 5 5 0 Prefoldin subunit Tropomyosin PF00261.15 CBK20488.2 - 1.2 8.1 45.9 2.3 7.2 27.3 3.1 1 1 1 2 2 2 0 Tropomyosin Filament PF00038.16 CBK20488.2 - 1.6 8.0 45.5 22 4.3 31.6 2.1 1 1 0 1 1 1 0 Intermediate filament protein DivIC PF04977.10 CBK20488.2 - 1.9 8.0 43.6 0.27 10.7 1.5 5.7 1 1 4 6 6 6 0 Septum formation initiator Baculo_PEP_C PF04513.7 CBK20488.2 - 1.9 8.3 12.9 3.8 7.3 5.5 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 CBK20488.2 - 2 8.1 27.6 3.5 7.3 5.3 3.6 1 1 1 3 3 3 0 Laminin Domain II Tropomyosin_1 PF12718.2 CBK20488.2 - 2 8.2 52.5 7.8 6.3 9.0 3.5 1 1 3 4 4 4 0 Tropomyosin like Rab5-bind PF09311.6 CBK20488.2 - 3.2 7.6 48.4 1.5 8.7 18.1 3.4 1 1 0 2 2 2 0 Rabaptin-like protein HrpB7 PF09486.5 CBK20488.2 - 3.3 7.6 24.5 0.9 9.4 1.9 4.0 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF1515 PF07439.6 CBK20488.2 - 3.6 7.4 15.3 1.7 8.4 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Atg14 PF10186.4 CBK20488.2 - 3.9 6.3 39.8 0.5 9.2 13.6 2.9 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBK20488.2 - 3.9 7.0 55.5 37 3.8 17.8 2.9 1 1 1 2 2 2 0 IncA protein HEAT_2 PF13646.1 CBK20489.2 - 7.3e-06 26.1 0.1 0.26 11.6 0.0 3.1 2 2 0 2 2 2 2 HEAT repeats V-ATPase_H_N PF03224.9 CBK20489.2 - 0.029 13.5 4.3 0.051 12.6 3.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 CBK20489.2 - 0.27 9.4 4.7 0.39 8.9 2.9 1.5 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit Ras PF00071.17 CBK20490.2 - 6.2e-15 54.9 0.2 7e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK20490.2 - 0.007 16.8 0.0 0.0073 16.7 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK20490.2 - 0.015 14.5 0.1 0.017 14.3 0.1 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family Toxin_56 PF15534.1 CBK20490.2 - 0.018 15.5 0.2 0.02 15.3 0.1 1.1 1 0 0 1 1 1 0 Putative toxin 56 zf-C3HC4_4 PF15227.1 CBK20491.2 - 5.2e-07 29.4 12.8 1.8e-06 27.7 8.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBK20491.2 - 7.3e-06 25.5 11.3 1.6e-05 24.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 CBK20491.2 - 1.3e-05 24.6 8.5 2.2e-05 23.8 4.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 CBK20491.2 - 1.5e-05 24.9 13.8 3.5e-05 23.7 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK20491.2 - 4.3e-05 23.2 13.1 0.00011 21.8 9.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBK20491.2 - 9.6e-05 21.9 13.8 0.00024 20.7 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20491.2 - 0.00098 18.8 14.7 0.0012 18.5 9.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBK20491.2 - 0.0015 18.1 11.1 0.0015 18.1 7.7 2.4 3 0 0 3 3 3 1 RING-type zinc-finger BRCT PF00533.21 CBK20491.2 - 0.02 15.0 1.3 0.25 11.5 0.0 3.0 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain zf-rbx1 PF12678.2 CBK20491.2 - 0.17 12.0 6.4 0.49 10.5 4.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBK20491.2 - 1.1 8.8 10.0 2.3 7.8 6.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain S1-P1_nuclease PF02265.11 CBK20492.2 - 8.6e-17 61.5 0.2 1e-16 61.3 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Glyco_transf_7C PF02709.9 CBK20494.2 - 0.0088 15.4 0.1 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase BPL_LplA_LipB PF03099.14 CBK20495.2 - 5.5e-17 61.9 0.1 9.2e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CBK20495.2 - 2.2e-08 33.6 0.0 5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain TPR_14 PF13428.1 CBK20496.2 - 1.9e-07 31.1 3.5 0.0013 19.1 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBK20496.2 - 2.3e-07 30.3 3.8 0.041 13.5 0.2 3.5 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 CBK20496.2 - 7.3e-06 26.2 2.1 0.0019 18.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20496.2 - 9e-06 25.2 4.0 0.013 15.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBK20496.2 - 1.1e-05 25.4 3.2 0.0041 17.2 0.4 3.1 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBK20496.2 - 0.00011 21.6 5.2 0.011 15.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK20496.2 - 0.00087 19.3 0.8 0.18 12.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20496.2 - 0.00095 19.0 5.1 0.31 11.0 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK20496.2 - 0.0025 17.6 1.2 3.8 7.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK20496.2 - 0.0035 17.0 0.7 0.027 14.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20496.2 - 0.0051 17.4 2.9 0.032 14.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK20496.2 - 0.01 16.2 2.2 0.25 11.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBK20496.2 - 0.017 15.2 3.0 0.046 13.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK20496.2 - 0.039 13.8 2.4 0.87 9.5 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Lipase_bact_N PF12262.3 CBK20496.2 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal UFD1 PF03152.9 CBK20497.2 - 6.3e-05 22.1 0.0 7.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.20 CBK20498.2 - 1.7e-36 125.7 0.0 1.9e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20498.2 - 1.6e-12 47.0 0.0 1.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBK20498.2 - 0.016 14.0 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.3 CBK20498.2 - 0.016 14.6 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 CBK20498.2 - 0.05 13.1 0.6 0.065 12.7 0.4 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CBK20498.2 - 0.055 13.1 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1725 PF08333.6 CBK20498.2 - 4.7 6.6 5.8 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) He_PIG PF05345.7 CBK20499.2 - 9.4e-14 51.1 16.0 5e-05 23.2 0.0 6.6 6 0 0 6 6 6 4 Putative Ig domain PA14 PF07691.7 CBK20499.2 - 1.8e-10 40.5 0.0 4.4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 PA14 domain RabGAP-TBC PF00566.13 CBK20500.2 - 8.7e-48 162.6 0.7 1.4e-47 161.9 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GDI PF00996.13 CBK20501.2 - 9.3e-165 548.1 0.8 1.2e-164 547.8 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 CBK20501.2 - 0.0022 16.9 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Exo5 PF09810.4 CBK20501.2 - 0.021 14.0 0.1 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Amino_oxidase PF01593.19 CBK20501.2 - 0.023 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBK20501.2 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CBK20501.2 - 0.082 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain N6-adenineMlase PF10237.4 CBK20501.2 - 0.097 12.3 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Probable N6-adenine methyltransferase Pkinase PF00069.20 CBK20502.2 - 6.5e-50 169.6 0.1 3.6e-49 167.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20502.2 - 6.1e-25 87.7 0.0 9.2e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20502.2 - 0.024 13.5 0.1 0.051 12.5 0.1 1.5 1 1 0 1 1 1 0 Kinase-like PHD PF00628.24 CBK20503.2 - 7.5e-12 44.7 11.0 1.4e-11 43.8 5.8 2.4 2 0 0 2 2 2 1 PHD-finger SET PF00856.23 CBK20503.2 - 0.00024 21.4 0.0 0.0081 16.4 0.0 2.4 1 1 0 1 1 1 1 SET domain Prok-RING_1 PF14446.1 CBK20503.2 - 0.0015 18.2 0.7 0.0015 18.2 0.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBK20503.2 - 1.4 8.2 10.3 0.11 11.8 3.3 2.1 2 1 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 CBK20503.2 - 3.2 7.6 7.9 18 5.2 5.5 2.1 1 1 0 1 1 1 0 Ring finger domain DUF2116 PF09889.4 CBK20503.2 - 6.8 6.5 10.5 0.79 9.5 1.4 2.6 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_S13_N PF08069.7 CBK20504.2 - 1.8e-28 98.1 1.9 2.9e-28 97.4 0.1 2.1 3 0 0 3 3 3 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBK20504.2 - 6.4e-23 80.3 0.2 1e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 GrpE PF01025.14 CBK20505.2 - 1e-39 135.7 0.1 1.4e-39 135.3 0.1 1.0 1 0 0 1 1 1 1 GrpE Prefoldin PF02996.12 CBK20505.2 - 0.0015 18.1 7.0 0.0017 17.9 1.9 2.6 3 0 0 3 3 3 1 Prefoldin subunit Lge1 PF11488.3 CBK20505.2 - 0.004 17.3 0.5 0.058 13.5 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 Myosin_tail_1 PF01576.14 CBK20505.2 - 0.0042 14.8 1.2 0.0049 14.6 0.8 1.0 1 0 0 1 1 1 1 Myosin tail DUF3391 PF11871.3 CBK20505.2 - 0.019 15.1 0.6 0.032 14.4 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2913 PF11140.3 CBK20505.2 - 0.021 14.1 0.3 0.031 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) FlxA PF14282.1 CBK20505.2 - 0.041 13.8 1.1 0.041 13.8 0.8 1.5 2 0 0 2 2 2 0 FlxA-like protein CHDCT2 PF08074.6 CBK20505.2 - 0.088 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CCDC-167 PF15188.1 CBK20505.2 - 0.14 12.1 1.7 0.25 11.2 1.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF342 PF03961.8 CBK20505.2 - 0.14 10.5 1.5 5.6 5.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 CBK20505.2 - 0.19 11.2 3.2 0.36 10.3 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.11 CBK20506.2 - 5.8e-16 58.1 31.9 5.8e-16 58.1 22.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CBK20506.2 - 5.3e-06 26.0 15.5 5.3e-06 26.0 10.8 3.1 3 2 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_2 PF13347.1 CBK20506.2 - 0.071 11.4 33.1 0.013 13.8 4.6 3.1 1 1 1 3 3 3 0 MFS/sugar transport protein Pex24p PF06398.6 CBK20506.2 - 6 5.5 6.4 1.3 7.7 1.9 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Ins134_P3_kin PF05770.6 CBK20507.2 - 5.4e-28 97.8 0.1 7.2e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase AAA_2 PF07724.9 CBK20508.2 - 4.7e-54 182.8 0.0 4.5e-52 176.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBK20508.2 - 2e-27 96.0 0.2 1.4e-15 57.6 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBK20508.2 - 2.6e-21 75.2 2.0 1e-20 73.4 0.1 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBK20508.2 - 1.5e-16 60.3 0.2 9.7e-11 41.5 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBK20508.2 - 3.1e-14 53.3 3.0 6.3e-05 23.0 0.0 4.7 3 2 2 5 5 5 3 AAA ATPase domain Clp_N PF02861.15 CBK20508.2 - 6.4e-13 48.4 0.1 5.8e-05 22.9 0.0 3.6 3 0 0 3 3 3 2 Clp amino terminal domain AAA_22 PF13401.1 CBK20508.2 - 1.6e-12 47.7 0.5 0.00015 21.8 0.0 4.2 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CBK20508.2 - 2.8e-09 36.9 0.0 0.00086 19.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBK20508.2 - 1.5e-08 34.2 0.0 0.0054 16.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBK20508.2 - 7.1e-07 28.8 0.0 0.00015 21.2 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CBK20508.2 - 1.5e-06 28.9 9.1 0.00097 19.9 0.0 4.4 4 1 1 5 5 2 1 AAA domain Zeta_toxin PF06414.7 CBK20508.2 - 1.7e-05 24.0 0.0 0.0013 17.9 0.0 3.2 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 CBK20508.2 - 1.7e-05 24.5 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 CBK20508.2 - 2.7e-05 24.4 12.4 0.026 14.8 0.0 4.3 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CBK20508.2 - 3.4e-05 23.3 0.0 0.19 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBK20508.2 - 3.5e-05 23.4 0.0 0.17 11.6 0.1 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CBK20508.2 - 7.6e-05 22.8 0.0 0.31 11.2 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Arch_ATPase PF01637.13 CBK20508.2 - 0.0001 22.0 12.3 0.077 12.6 0.5 4.9 3 3 0 3 3 2 2 Archaeal ATPase DUF815 PF05673.8 CBK20508.2 - 0.00015 20.7 0.1 0.015 14.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBK20508.2 - 0.0003 19.9 2.9 0.093 11.7 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 CBK20508.2 - 0.00057 19.5 0.0 0.34 10.6 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CBK20508.2 - 0.0012 17.8 0.0 0.0069 15.3 0.0 2.2 2 1 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 CBK20508.2 - 0.0012 18.0 0.0 1.8 7.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 CBK20508.2 - 0.0017 18.3 5.1 0.55 10.1 0.0 4.0 4 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 CBK20508.2 - 0.002 17.3 0.0 1.6 7.8 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBK20508.2 - 0.0026 17.6 0.0 1.3 8.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 CBK20508.2 - 0.0033 17.2 0.0 0.54 10.0 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CBK20508.2 - 0.0033 17.0 0.0 3 7.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CBK20508.2 - 0.0044 16.9 0.3 0.97 9.4 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase DNA_pol3_delta2 PF13177.1 CBK20508.2 - 0.0082 15.8 0.0 0.096 12.3 0.0 2.8 2 1 0 2 2 1 1 DNA polymerase III, delta subunit NTPase_1 PF03266.10 CBK20508.2 - 0.014 15.1 0.1 4.8 6.8 0.0 3.0 3 0 0 3 3 2 0 NTPase Miro PF08477.8 CBK20508.2 - 0.014 15.8 0.2 2.8 8.4 0.0 3.5 3 0 0 3 3 3 0 Miro-like protein AAA_10 PF12846.2 CBK20508.2 - 0.015 14.7 6.5 0.17 11.3 0.1 4.3 3 2 0 4 4 4 0 AAA-like domain AAA_24 PF13479.1 CBK20508.2 - 0.017 14.6 0.0 2.5 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CBK20508.2 - 0.019 14.3 5.1 0.28 10.6 0.0 3.5 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain PhoH PF02562.11 CBK20508.2 - 0.023 13.9 0.0 0.72 9.0 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein UPF0079 PF02367.12 CBK20508.2 - 0.034 13.7 0.0 6.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Ras PF00071.17 CBK20508.2 - 0.05 12.9 0.1 19 4.6 0.0 3.3 3 0 0 3 3 3 0 Ras family AAA_29 PF13555.1 CBK20508.2 - 0.054 13.0 0.0 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CBK20508.2 - 0.19 12.0 0.0 0.19 12.0 0.0 4.6 3 1 0 3 3 2 0 AAA domain DUF515 PF04415.7 CBK20508.2 - 0.28 9.3 7.8 0.71 8.0 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF87 PF01935.12 CBK20508.2 - 0.36 10.5 7.3 0.5 10.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF87 DUF4108 PF13390.1 CBK20508.2 - 1.4 8.6 7.1 5.2 6.7 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF4108) ABC_tran PF00005.22 CBK20508.2 - 1.4 9.2 8.1 2 8.7 0.0 3.7 4 2 0 4 4 2 0 ABC transporter Arf PF00025.16 CBK20510.2 - 3.3e-65 218.5 0.1 3.8e-65 218.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBK20510.2 - 2.1e-15 56.3 6.6 2.2e-10 39.8 0.7 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBK20510.2 - 5.3e-11 42.1 0.0 6.4e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBK20510.2 - 5e-10 38.9 0.0 6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBK20510.2 - 1.6e-09 37.2 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBK20510.2 - 1.1e-08 35.5 0.0 1.6e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK20510.2 - 9.4e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK20510.2 - 1.8e-05 24.2 0.0 0.00066 19.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBK20510.2 - 0.014 14.7 0.1 0.055 12.7 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CBK20510.2 - 0.022 14.2 0.1 0.069 12.6 0.0 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBK20510.2 - 0.029 13.8 0.0 0.71 9.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 CBK20510.2 - 0.04 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Arch_ATPase PF01637.13 CBK20510.2 - 0.095 12.3 0.4 0.2 11.3 0.2 1.5 1 1 1 2 2 2 0 Archaeal ATPase WD40 PF00400.27 CBK20512.2 - 3.8e-17 61.4 9.4 5.5e-08 32.3 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 CBK20512.2 - 0.11 12.1 0.5 0.42 10.2 0.0 2.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CBK20513.2 - 4.5e-60 197.5 18.6 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK20513.2 - 4.3e-05 21.8 8.9 0.0062 14.7 0.1 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK20513.2 - 0.002 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK20513.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK20513.2 - 0.0071 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK20513.2 - 0.011 14.6 0.2 0.45 9.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Gmad1 PF10647.4 CBK20513.2 - 0.067 12.5 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK20513.2 - 0.068 13.4 0.1 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Ribosomal_L37e PF01907.14 CBK20514.2 - 2.2e-26 91.3 11.2 2.2e-26 91.3 7.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CBK20514.2 - 0.0028 17.4 1.1 0.0041 16.9 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon AMOP PF03782.12 CBK20514.2 - 0.029 14.3 0.5 0.034 14.1 0.3 1.1 1 0 0 1 1 1 0 AMOP domain HypA PF01155.14 CBK20514.2 - 0.051 13.2 0.2 0.068 12.8 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S14 PF00253.16 CBK20514.2 - 0.36 10.2 9.5 4 6.9 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e GFA PF04828.9 CBK20514.2 - 0.83 9.6 4.4 5.7 6.9 2.9 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Actin PF00022.14 CBK20515.2 - 6.8e-146 485.7 0.0 7.7e-146 485.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK20515.2 - 0.0072 14.9 0.0 0.025 13.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Methyltransf_29 PF03141.11 CBK20515.2 - 0.042 12.1 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 CBK20515.2 - 0.1 13.0 0.0 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) POR_N PF01855.14 CBK20516.2 - 6.5e-72 241.7 0.5 2.6e-71 239.8 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.15 CBK20516.2 - 2.3e-43 148.1 0.0 3.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBK20516.2 - 2.8e-25 88.9 0.1 7e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin EKR PF10371.4 CBK20516.2 - 5.1e-21 73.9 0.2 4.4e-20 71.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function POR PF01558.13 CBK20516.2 - 4.7e-20 72.1 0.0 1.5e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.16 CBK20516.2 - 1.7e-08 35.0 0.0 6.5e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.1 CBK20516.2 - 3.5e-08 33.5 10.5 0.0011 19.1 1.3 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK20516.2 - 1e-07 32.1 9.9 1e-07 32.1 6.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK20516.2 - 1.7e-07 31.8 8.9 0.0036 18.0 1.2 3.0 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.16 CBK20516.2 - 2.2e-07 30.5 0.1 5.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK20516.2 - 1.6e-06 27.4 23.8 0.00015 21.1 3.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.1 CBK20516.2 - 2.4e-06 27.2 8.8 2.4e-06 27.2 6.1 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK20516.2 - 8.1e-06 25.7 0.2 2.9e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 Transketolase, C-terminal domain Fer4_8 PF13183.1 CBK20516.2 - 1.1e-05 25.4 7.9 3.7e-05 23.6 5.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 CBK20516.2 - 4.3e-05 23.7 7.1 0.017 15.4 1.5 3.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CBK20516.2 - 9.7e-05 22.1 14.2 0.001 18.9 9.9 2.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK20516.2 - 0.00025 20.7 7.0 0.00025 20.7 4.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBK20516.2 - 0.00034 20.9 5.9 0.086 13.2 0.2 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK20516.2 - 0.00045 19.9 18.1 0.0013 18.5 1.7 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Flavodoxin_5 PF12724.2 CBK20516.2 - 0.082 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain GSH-S_N PF02951.9 CBK20516.2 - 0.088 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Fer4_15 PF13459.1 CBK20516.2 - 2 9.0 11.5 3.4 8.3 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain PseudoU_synth_1 PF01416.15 CBK20517.2 - 5.1e-13 49.3 0.0 1e-11 45.1 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase GTP_EFTU PF00009.22 CBK20518.2 - 1.7e-56 190.6 0.0 2.3e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK20518.2 - 1e-33 115.4 0.1 3.1e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK20518.2 - 5.6e-10 39.1 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK20518.2 - 0.00011 22.1 0.1 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK20518.2 - 0.029 13.5 0.4 0.072 12.2 0.1 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK20518.2 - 0.04 14.4 0.4 0.61 10.5 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein Glyco_hydro_35 PF01301.14 CBK20519.2 - 1.6e-112 375.9 1.7 2e-112 375.6 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBK20519.2 - 3e-14 52.9 0.1 1.2e-12 47.6 0.1 2.4 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.13 CBK20519.2 - 0.049 12.8 0.2 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NIF PF03031.13 CBK20520.2 - 3.7e-37 127.4 0.9 1.2e-36 125.8 0.6 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.20 CBK20521.2 - 7e-40 136.8 0.0 8.8e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20521.2 - 5.6e-09 35.4 0.0 9.4e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20521.2 - 0.042 12.7 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 CBK20521.2 - 0.053 13.2 0.0 4.8 6.8 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Thioredoxin PF00085.15 CBK20522.2 - 7.7e-05 22.3 0.1 8.4e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Sep15_SelM PF08806.6 CBK20522.2 - 0.049 13.3 0.0 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 Sep15/SelM redox domain Thioredoxin_6 PF13848.1 CBK20522.2 - 0.12 12.1 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.15 CBK20523.2 - 0.00015 21.3 0.1 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBK20523.2 - 0.033 14.2 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK20523.2 - 0.045 13.8 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK20523.2 - 0.13 12.4 0.1 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain EF-hand_7 PF13499.1 CBK20524.2 - 1.2e-12 47.7 0.4 3.4e-06 27.0 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBK20524.2 - 3.1e-11 42.1 1.1 1.5e-05 24.4 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBK20524.2 - 1.2e-10 39.8 0.2 4.2e-05 22.5 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBK20524.2 - 2.8e-08 32.7 1.4 0.0086 15.3 0.0 3.0 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBK20524.2 - 1.9e-07 30.5 2.7 0.42 10.2 0.0 4.0 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 CBK20524.2 - 0.00038 20.3 0.0 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 CBK20524.2 - 0.018 14.5 0.2 0.94 9.0 0.0 2.2 1 1 1 2 2 2 0 Caleosin related protein ArdA PF07275.6 CBK20524.2 - 0.044 14.0 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein (ArdA) GTPase_Cys_C PF12631.2 CBK20524.2 - 0.085 13.2 0.1 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Got1 PF04178.7 CBK20525.2 - 3.3e-22 78.8 16.2 4.5e-22 78.3 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family MARVEL PF01284.18 CBK20525.2 - 0.14 11.9 5.6 0.3 10.9 3.9 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF2628 PF10947.3 CBK20525.2 - 7.2 6.4 9.6 8.9 6.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) RAI16-like PF10257.4 CBK20527.2 - 4.5e-05 22.5 0.2 6.7e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein GAS PF13851.1 CBK20527.2 - 0.017 14.3 1.0 0.027 13.6 0.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nnf1 PF03980.9 CBK20527.2 - 0.055 13.4 1.9 0.071 13.1 1.3 1.3 1 1 0 1 1 1 0 Nnf1 DUF1759 PF03564.10 CBK20527.2 - 0.13 12.0 0.6 0.45 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Enolase_C PF00113.17 CBK20528.2 - 4.5e-150 498.5 0.1 7e-150 497.9 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBK20528.2 - 3.5e-56 188.7 0.5 5.5e-56 188.1 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CBK20528.2 - 2.2e-05 23.5 0.1 3.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CBK20528.2 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like Alpha-amylase PF00128.19 CBK20529.2 - 0.053 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 CBK20529.2 - 0.096 12.8 0.0 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Thioredoxin_7 PF13899.1 CBK20530.2 - 2.3e-10 40.3 0.0 3.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK20530.2 - 0.00045 20.3 0.0 0.00082 19.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 CBK20530.2 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4117 PF13491.1 CBK20530.2 - 0.067 12.6 7.0 0.11 11.9 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) DUF1129 PF06570.6 CBK20530.2 - 1.7 7.9 4.8 2.7 7.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ICMT PF04140.9 CBK20531.2 - 8.9e-22 77.1 1.0 8.9e-22 77.1 0.7 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBK20531.2 - 2e-11 43.9 2.5 2e-11 43.9 1.7 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase Frag1 PF10277.4 CBK20531.2 - 7.8e-09 35.3 10.3 7.8e-09 35.3 7.2 3.0 2 1 1 3 3 3 1 Frag1/DRAM/Sfk1 family DUF1295 PF06966.7 CBK20531.2 - 0.00022 20.6 1.7 0.00046 19.5 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ada_Zn_binding PF02805.11 CBK20531.2 - 0.024 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 Metal binding domain of Ada VHP PF02209.14 CBK20531.2 - 0.029 14.0 0.8 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 Villin headpiece domain DAP3 PF10236.4 CBK20532.2 - 1.6e-29 102.8 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CBK20532.2 - 5e-05 23.3 0.0 0.00019 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBK20532.2 - 0.0073 16.4 0.0 0.034 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK20532.2 - 0.023 14.6 0.0 0.081 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK20532.2 - 0.038 13.6 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 CBK20532.2 - 0.045 13.4 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK20532.2 - 0.068 13.4 0.1 0.29 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain Actin PF00022.14 CBK20533.2 - 8.7e-101 337.1 0.0 1.1e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBK20533.2 - 0.16 12.3 0.1 0.53 10.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Collagen PF01391.13 CBK20534.2 - 5.7e-31 105.8 107.0 6.2e-10 38.4 18.8 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) MerC PF03203.9 CBK20535.2 - 0.013 15.8 4.9 0.018 15.3 3.4 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein SPC25 PF06703.6 CBK20535.2 - 0.12 11.9 1.6 0.2 11.2 1.1 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TMEM190 PF15431.1 CBK20535.2 - 0.17 11.8 0.8 0.3 11.0 0.5 1.6 1 0 0 1 1 1 0 Transmembrane protein 190 DUF4064 PF13273.1 CBK20535.2 - 0.64 10.1 4.8 0.51 10.4 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) PRA1 PF03208.14 CBK20535.2 - 5.5 6.3 10.2 7.4 5.8 6.5 1.5 1 1 0 1 1 1 0 PRA1 family protein DUF3816 PF12822.2 CBK20535.2 - 8 6.3 13.2 12 5.7 9.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Reo_sigmaC PF04582.7 CBK20536.2 - 0.0028 16.9 2.8 0.17 11.0 0.5 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein DUF4200 PF13863.1 CBK20536.2 - 0.0082 16.0 59.8 0.13 12.1 16.6 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) DUF1843 PF08898.5 CBK20536.2 - 0.039 13.9 1.7 0.039 13.9 1.2 4.5 4 2 1 5 5 4 0 Domain of unknown function (DUF1843) Tropomyosin PF00261.15 CBK20536.2 - 0.51 9.3 55.0 5.3 6.0 18.9 2.7 1 1 1 2 2 2 0 Tropomyosin DUF4407 PF14362.1 CBK20536.2 - 0.67 8.8 38.3 0.31 9.9 14.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 CBK20536.2 - 1.1 9.0 60.6 0.11 12.3 17.7 2.6 1 1 1 2 2 2 0 Tropomyosin like Laminin_II PF06009.7 CBK20536.2 - 1.5 8.5 25.9 2.1 8.1 7.0 2.6 2 1 0 2 2 2 0 Laminin Domain II Rootletin PF15035.1 CBK20536.2 - 1.6 8.7 55.7 0.27 11.1 10.8 3.5 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 CBK20536.2 - 1.6 8.5 12.1 0.69 9.7 2.5 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 CBK20536.2 - 3.7 6.9 54.1 0.33 10.3 18.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein Mga PF05043.8 CBK20536.2 - 3.9 7.8 16.7 0.26 11.5 4.8 3.2 2 2 2 4 4 4 0 Mga helix-turn-helix domain DUF3584 PF12128.3 CBK20536.2 - 4.7 4.4 47.9 32 1.6 33.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 CBK20536.2 - 5.1 6.9 55.2 0.65 9.8 12.4 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HrpB7 PF09486.5 CBK20536.2 - 6.6 6.6 33.2 4.7 7.1 9.5 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HOOK PF05622.7 CBK20536.2 - 6.7 4.3 51.0 3.8 5.2 12.3 2.0 1 1 1 2 2 2 0 HOOK protein ERM PF00769.14 CBK20536.2 - 6.9 6.1 61.8 1 8.8 25.8 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Lectin_N PF03954.9 CBK20536.2 - 8.6 5.7 17.8 6.8 6.0 5.4 2.6 2 2 0 2 2 2 0 Hepatic lectin, N-terminal domain Nuc_sug_transp PF04142.10 CBK20537.2 - 8.1e-09 34.9 0.5 8.1e-09 34.9 0.3 2.5 3 0 0 3 3 3 1 Nucleotide-sugar transporter EamA PF00892.15 CBK20537.2 - 2e-05 24.6 0.8 2e-05 24.6 0.5 4.2 5 1 0 5 5 5 1 EamA-like transporter family Dispanin PF04505.7 CBK20537.2 - 0.14 11.6 1.2 0.63 9.6 0.1 2.5 2 0 0 2 2 2 0 Interferon-induced transmembrane protein SDH_alpha PF03313.10 CBK20538.2 - 3.2e-82 275.7 8.9 5.1e-82 275.1 6.2 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CBK20538.2 - 1.4e-19 70.7 0.2 1.7e-08 34.6 0.0 2.4 1 1 1 2 2 2 2 Serine dehydratase beta chain CBM_X2 PF03442.9 CBK20538.2 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 MmgE_PrpD PF03972.9 CBK20538.2 - 0.056 11.6 1.1 0.075 11.1 0.7 1.2 1 0 0 1 1 1 0 MmgE/PrpD family RF-1 PF00472.15 CBK20539.2 - 1.5e-32 111.7 0.2 2.5e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CBK20539.2 - 6.9e-27 93.4 0.0 1.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 PCRF domain C1_1 PF00130.17 CBK20540.2 - 6.5e-07 28.9 2.0 1.2e-06 28.1 1.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Apt1 PF10351.4 CBK20540.2 - 0.0024 16.8 0.2 0.0024 16.8 0.1 1.3 2 0 0 2 2 2 1 Golgi-body localisation protein domain C1_3 PF07649.7 CBK20540.2 - 0.0032 17.4 1.9 0.0054 16.7 1.3 1.4 1 0 0 1 1 1 1 C1-like domain FYVE PF01363.16 CBK20540.2 - 0.027 14.3 0.9 0.048 13.5 0.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger C1_2 PF03107.11 CBK20540.2 - 0.16 12.0 3.6 0.28 11.3 2.5 1.4 1 0 0 1 1 1 0 C1 domain Tnp_zf-ribbon_2 PF13842.1 CBK20540.2 - 0.43 11.0 4.1 0.79 10.1 2.5 1.7 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Pkinase PF00069.20 CBK20541.2 - 2.1e-44 151.6 0.2 3.1e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20541.2 - 1.5e-35 122.5 0.1 2.1e-35 122.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK20541.2 - 4.6e-06 25.8 0.0 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK20541.2 - 0.00051 19.4 0.1 0.0014 18.0 0.0 1.7 1 1 0 2 2 2 1 RIO1 family APH PF01636.18 CBK20541.2 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4468 PF14730.1 CBK20541.2 - 0.081 12.6 0.9 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold LRR_6 PF13516.1 CBK20542.2 - 1.1e-26 89.8 13.7 0.081 13.0 0.0 12.5 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.2 CBK20542.2 - 2.5e-16 58.8 24.2 8.7e-05 22.0 0.6 8.1 6 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK20542.2 - 1.7e-07 30.8 30.5 0.16 11.7 0.9 9.9 4 3 4 8 8 8 4 Leucine rich repeat LRR_1 PF00560.28 CBK20542.2 - 4.5e-07 29.0 19.4 0.46 10.7 0.1 10.6 10 2 1 11 11 11 2 Leucine Rich Repeat LRR_7 PF13504.1 CBK20542.2 - 1.7e-06 27.2 15.6 27 5.5 0.0 10.2 11 0 0 11 11 11 0 Leucine rich repeat F-box PF00646.28 CBK20542.2 - 0.026 14.1 0.0 0.083 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain LRR_9 PF14580.1 CBK20542.2 - 0.093 12.2 2.4 1.4 8.4 0.4 3.2 3 2 1 4 4 4 0 Leucine-rich repeat zf-MYND PF01753.13 CBK20543.2 - 5e-08 32.6 13.2 5e-08 32.6 9.1 2.8 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.11 CBK20543.2 - 6.9e-05 22.4 8.0 6.9e-05 22.4 5.6 3.1 3 0 0 3 3 3 1 HIT zinc finger Ldh_1_C PF02866.13 CBK20544.2 - 1.9e-24 86.3 0.0 2.5e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBK20544.2 - 2.6e-22 79.1 0.0 5.9e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain vATP-synt_AC39 PF01992.11 CBK20546.2 - 1.3e-53 182.2 0.0 5e-52 177.0 0.0 2.0 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit S4 PF01479.20 CBK20547.2 - 7.4e-13 47.7 0.0 1.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 CBK20547.2 - 0.00062 20.1 2.7 0.001 19.3 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain NIT PF08376.5 CBK20547.2 - 0.042 13.3 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing TSP9 PF11493.3 CBK20548.2 - 0.00032 21.1 0.6 0.00067 20.1 0.4 1.5 1 0 0 1 1 1 1 Thylakoid soluble phosphoprotein TSP9 Filament PF00038.16 CBK20549.2 - 1.5e-15 57.5 289.5 0.00021 20.8 34.9 10.5 2 1 8 11 11 11 7 Intermediate filament protein AAA_13 PF13166.1 CBK20549.2 - 3.4e-08 32.4 257.5 5.2e-06 25.2 25.2 8.0 1 1 7 8 8 8 7 AAA domain Tropomyosin PF00261.15 CBK20549.2 - 1e-05 24.7 34.2 1e-05 24.7 23.7 11.4 1 1 10 11 11 5 2 Tropomyosin DUF3584 PF12128.3 CBK20549.2 - 0.0001 19.8 116.8 0.00023 18.6 40.6 7.0 1 1 6 7 7 7 4 Protein of unknown function (DUF3584) Atg14 PF10186.4 CBK20549.2 - 0.00041 19.3 20.6 0.00041 19.3 14.3 13.7 2 1 11 14 14 14 2 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 CBK20549.2 - 0.00086 18.7 23.4 0.00086 18.7 16.2 16.4 3 3 11 16 16 15 6 Domain of unknown function (DUF4201) WEMBL PF05701.6 CBK20549.2 - 0.00095 17.7 92.3 0.0017 16.9 28.4 7.9 1 1 6 7 7 6 4 Weak chloroplast movement under blue light Apolipoprotein PF01442.13 CBK20549.2 - 0.0032 17.0 36.5 0.0032 17.0 25.3 9.5 1 1 7 8 8 7 2 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.6 CBK20549.2 - 0.0046 16.3 4.9 0.0046 16.3 3.4 16.2 6 3 12 18 18 17 1 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 CBK20549.2 - 0.61 9.6 359.7 0.0086 15.6 13.0 14.8 1 1 13 15 15 14 0 IncA protein Myosin_tail_1 PF01576.14 CBK20549.2 - 2.7 5.6 332.4 0.14 9.8 58.2 6.8 1 1 4 6 6 6 0 Myosin tail KH_5 PF13184.1 CBK20549.2 - 5 6.9 7.8 44 3.9 0.2 5.3 5 0 0 5 5 5 0 NusA-like KH domain G-patch PF01585.18 CBK20550.2 - 3.1e-10 39.6 1.2 4.9e-10 39.0 0.8 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK20550.2 - 4.9e-08 32.7 0.7 6.9e-08 32.2 0.5 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site GCFC PF07842.7 CBK20551.2 - 3.2e-12 46.4 0.2 3.2e-12 46.4 0.1 2.6 3 1 0 3 3 3 1 GC-rich sequence DNA-binding factor-like protein Pox_H7 PF04787.7 CBK20551.2 - 0.0013 18.5 0.2 0.82 9.4 0.0 2.4 2 0 0 2 2 2 2 Late protein H7 Ribosomal_L18ae PF01775.12 CBK20552.2 - 1e-41 141.6 0.4 1.6e-41 141.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ribosomal_S5 PF00333.15 CBK20553.2 - 4e-26 90.5 2.2 4e-26 90.5 1.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBK20553.2 - 2.9e-24 84.1 0.0 5.1e-24 83.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain TPR_15 PF13429.1 CBK20554.2 - 0.042 12.9 2.1 0.63 9.0 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20554.2 - 0.056 14.1 2.7 0.8 10.5 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBK20554.2 - 0.071 12.2 0.6 1.4 8.0 0.1 2.4 2 1 1 3 3 3 0 Coatomer epsilon subunit HSP70 PF00012.15 CBK20555.2 - 1.1e-100 337.2 0.0 1.4e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20555.2 - 6.1e-19 67.7 0.1 4.4e-17 61.6 0.1 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK20555.2 - 0.0085 15.9 0.5 8.4 6.2 0.0 3.6 4 0 0 4 4 4 1 Cell division protein FtsA OrfB_IS605 PF01385.14 CBK20555.2 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Probable transposase Hydantoinase_A PF01968.13 CBK20555.2 - 0.021 13.9 0.7 0.48 9.4 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CBK20555.2 - 0.029 14.0 0.1 0.062 12.9 0.1 1.7 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CBK20555.2 - 0.13 11.1 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Ketoacyl-synt_C PF02801.17 CBK20555.2 - 0.15 11.9 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Peptidase_C1 PF00112.18 CBK20556.2 - 9.1e-67 225.1 0.1 1.2e-66 224.7 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK20556.2 - 5.5e-10 39.3 0.6 1e-09 38.5 0.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBK20556.2 - 1.1e-06 27.4 0.7 0.011 14.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-RING_4 PF14570.1 CBK20557.2 - 2.7e-13 49.2 13.2 2.7e-13 49.2 9.2 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 CBK20557.2 - 4.7e-09 35.7 0.0 7.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20557.2 - 3.9e-08 33.0 0.1 8.5e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20557.2 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CBK20557.2 - 8.3e-05 22.1 12.3 0.00029 20.4 8.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 CBK20557.2 - 0.012 14.8 0.4 0.032 13.5 0.3 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_2 PF13639.1 CBK20557.2 - 0.013 15.2 14.4 0.044 13.6 10.0 2.0 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.1 CBK20557.2 - 0.97 9.2 8.1 0.13 11.9 2.7 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 CBK20557.2 - 5.1 6.8 19.6 0.42 10.3 9.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DUF2034 PF10356.4 CBK20558.2 - 9.1e-15 54.3 0.4 1e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CBK20558.2 - 4.3e-08 32.9 0.0 6.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease ATP-synt_ab PF00006.20 CBK20559.2 - 3.5e-60 203.1 0.0 4.6e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK20559.2 - 5.1e-13 49.4 0.0 9.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK20559.2 - 2.9e-10 40.2 0.5 5.2e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBK20559.2 - 0.0032 17.3 0.1 0.0071 16.2 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain Pkinase PF00069.20 CBK20560.2 - 1.4e-49 168.5 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20560.2 - 1.2e-29 103.2 0.0 1.4e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20560.2 - 4.7e-10 38.9 0.0 6.5e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK20560.2 - 0.021 14.5 0.1 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CBK20560.2 - 0.092 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBK20561.2 - 0.00026 20.2 1.4 0.00073 18.7 0.6 1.9 2 1 0 2 2 2 1 Protein kinase domain PBD PF00786.23 CBK20561.2 - 0.00033 21.0 0.0 0.0008 19.7 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain DUF505 PF04458.7 CBK20561.2 - 0.002 16.3 0.0 0.0028 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) SHQ1 PF04925.10 CBK20561.2 - 0.026 13.9 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein NB-ARC PF00931.17 CBK20561.2 - 0.065 12.0 0.2 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF2873 PF11395.3 CBK20562.2 - 0.096 12.2 2.2 0.14 11.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Hydrolase PF00702.21 CBK20563.2 - 1.2e-20 74.8 0.0 9.2e-20 71.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBK20563.2 - 5.6e-20 71.3 0.0 5.5e-19 68.1 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBK20563.2 - 2.7e-15 57.0 0.0 6.3e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK20563.2 - 0.00017 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK20563.2 - 0.19 11.2 0.1 2.7 7.4 0.0 2.4 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Glycos_transf_2 PF00535.21 CBK20564.2 - 6.7e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBK20564.2 - 3.7e-05 23.6 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBK20564.2 - 0.016 14.6 0.1 0.056 12.9 0.1 2.0 1 1 0 1 1 1 0 N-terminal domain of galactosyltransferase MORN PF02493.15 CBK20565.2 - 8.9e-10 37.7 86.1 0.023 14.4 0.3 15.7 14 0 0 14 14 14 10 MORN repeat ABC2_membrane PF01061.19 CBK20566.2 - 1.5e-37 128.8 16.9 1.9e-37 128.4 11.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBK20566.2 - 0.00013 21.0 10.9 0.00013 21.0 7.6 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1546 PF07571.8 CBK20567.2 - 0.14 12.3 0.2 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) NPV_P10 PF05531.7 CBK20567.2 - 0.26 11.5 16.4 0.17 12.1 0.7 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 CBK20567.2 - 1.6 8.5 18.6 4.6 7.0 1.3 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ion_trans_2 PF07885.11 CBK20569.2 - 4.3e-06 26.3 1.0 1.5e-05 24.6 0.7 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 CBK20569.2 - 2.3e-05 24.2 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit SBDS PF01172.13 CBK20570.2 - 1.2e-27 95.5 0.1 2.9e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 CBK20570.2 - 7.8e-24 83.7 1.7 1.3e-23 83.0 1.2 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.3 CBK20570.2 - 0.025 14.6 2.1 0.06 13.5 1.5 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBK20570.2 - 0.042 13.9 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBK20570.2 - 0.13 12.0 4.4 0.17 11.6 0.3 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Ras PF00071.17 CBK20571.2 - 2.5e-48 163.5 0.1 3.4e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBK20571.2 - 7.5e-16 57.8 0.4 2.5e-15 56.1 0.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBK20571.2 - 1.2e-15 58.0 0.0 1.6e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBK20571.2 - 1.4e-07 31.1 0.0 2.9e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK20571.2 - 0.00027 20.8 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK20571.2 - 0.00046 19.4 0.1 0.0013 17.9 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBK20571.2 - 0.0027 16.8 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBK20571.2 - 0.0051 16.0 0.2 0.054 12.7 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Chordopox_A33R PF05966.7 CBK20571.2 - 0.0087 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Chordopoxvirus A33R protein DUF2688 PF10892.3 CBK20571.2 - 0.087 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) ABC_tran PF00005.22 CBK20571.2 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Peptidase_U35_2 PF14550.1 CBK20571.2 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative phage protease XkdF DUF4448 PF14610.1 CBK20572.2 - 0.00025 20.5 0.3 0.0018 17.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) He_PIG PF05345.7 CBK20572.2 - 0.0018 18.2 0.2 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 Putative Ig domain DUF3753 PF12575.3 CBK20572.2 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF912 PF06024.7 CBK20572.2 - 0.047 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 CBK20572.2 - 0.23 11.0 0.4 0.41 10.2 0.3 1.3 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 CBK20572.2 - 0.24 11.8 2.1 0.52 10.7 1.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HSP70 PF00012.15 CBK20573.2 - 3.5e-67 226.7 0.0 5.9e-67 225.9 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK20573.2 - 3e-10 39.2 0.0 1.1e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 CBK20573.2 - 0.17 10.7 0.0 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain TCR PF03638.10 CBK20575.2 - 2.4e-25 88.1 55.5 1.3e-12 47.3 18.1 2.6 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain SWIB PF02201.13 CBK20575.2 - 1.4e-12 47.0 1.2 1.9e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain SWIB PF02201.13 CBK20576.2 - 1.2e-26 92.1 0.0 1.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_S17 PF00366.15 CBK20577.2 - 6e-26 90.2 1.1 7.6e-26 89.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 NUDIX PF00293.23 CBK20578.2 - 1.1e-10 41.2 0.1 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.27 CBK20579.2 - 1.5e-14 52.0 1.6 3.3e-07 29.1 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBK20579.2 - 8.3e-14 50.1 1.6 4.1e-06 26.2 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBK20579.2 - 5e-13 48.4 1.2 1.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBK20579.2 - 4.3e-09 36.3 0.3 0.0044 17.1 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK20579.2 - 5.1e-07 28.7 4.6 3.7e-05 22.8 0.7 4.0 4 0 0 4 4 4 1 EF hand zf-MIZ PF02891.15 CBK20579.2 - 0.015 14.8 2.4 0.03 13.8 0.5 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Zn_Tnp_IS91 PF14319.1 CBK20579.2 - 0.063 12.7 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.7 CBK20579.2 - 0.19 11.5 1.1 0.45 10.3 0.4 1.8 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.1 CBK20579.2 - 0.32 10.7 2.2 1.4 8.6 1.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK20579.2 - 0.39 10.3 2.1 1.7 8.3 1.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 CBK20579.2 - 0.59 9.6 2.5 9.1 5.8 0.2 2.6 2 0 0 2 2 2 0 InsA N-terminal domain DNA_ligase_ZBD PF03119.11 CBK20579.2 - 2.6 7.8 5.7 3.7 7.3 0.5 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Orn_Arg_deC_N PF02784.11 CBK20580.2 - 1.9e-43 148.4 0.0 2.5e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBK20580.2 - 1.2e-12 47.5 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K_channel_TID PF07941.6 CBK20580.2 - 0.033 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3879 PF12995.2 CBK20580.2 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) PseudoU_synth_1 PF01416.15 CBK20581.2 - 2.6e-11 43.8 0.0 5.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 CBK20581.2 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ribonuc_red_lgN PF00317.16 CBK20583.2 - 0.03 14.1 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Mnd1 PF03962.10 CBK20583.2 - 0.062 12.9 1.9 0.098 12.3 1.3 1.3 1 0 0 1 1 1 0 Mnd1 family Rho_Binding PF08912.6 CBK20583.2 - 0.27 11.5 0.3 0.27 11.5 0.2 2.3 1 1 1 2 2 2 0 Rho Binding Ribosomal_60s PF00428.14 CBK20584.2 - 9.5e-19 67.5 11.3 1.3e-18 67.1 7.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Myc_N PF01056.13 CBK20584.2 - 0.0045 16.2 1.0 0.0049 16.0 0.7 1.1 1 0 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.6 CBK20584.2 - 0.021 14.0 2.6 0.024 13.9 1.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 CBK20584.2 - 0.51 9.9 4.4 0.67 9.5 3.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Exonuc_VIII PF06630.6 CBK20584.2 - 1 8.6 3.9 1.9 7.7 2.1 1.7 1 1 1 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII DAP3 PF10236.4 CBK20585.2 - 1.6e-29 102.8 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CBK20585.2 - 5e-05 23.3 0.0 0.00019 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBK20585.2 - 0.0073 16.4 0.0 0.034 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK20585.2 - 0.023 14.6 0.0 0.081 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK20585.2 - 0.038 13.6 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 CBK20585.2 - 0.045 13.4 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK20585.2 - 0.068 13.4 0.1 0.29 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain Aldo_ket_red PF00248.16 CBK20586.2 - 9.1e-49 165.7 0.0 1.2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Terminase_2 PF03592.11 CBK20586.2 - 0.16 12.2 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 Terminase small subunit SBDS_C PF09377.5 CBK20587.2 - 9.1e-10 38.3 0.2 1.3e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CBK20587.2 - 4.6e-09 35.9 0.2 8.1e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Band_7 PF01145.20 CBK20589.2 - 6.6e-35 120.6 5.7 6.6e-35 120.6 4.0 2.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBK20589.2 - 0.00022 20.8 0.4 0.00051 19.6 0.1 1.7 2 0 0 2 2 2 1 SPFH domain-Band 7 family Gemin7 PF11095.3 CBK20589.2 - 0.057 13.1 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SurA_N_2 PF13623.1 CBK20589.2 - 0.39 10.6 0.0 0.39 10.6 0.0 2.5 3 0 0 3 3 3 0 SurA N-terminal domain CBS PF00571.23 CBK20590.2 - 1.4e-19 69.5 0.6 0.0001 22.0 0.0 4.3 4 0 0 4 4 4 4 CBS domain AAA_12 PF13087.1 CBK20591.2 - 8.2e-59 198.3 0.1 8.3e-58 195.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBK20591.2 - 9.8e-49 166.0 1.8 1.8e-48 165.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.5 CBK20591.2 - 8.8e-27 93.5 5.5 2.5e-26 92.0 3.8 1.8 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.1 CBK20591.2 - 1.1e-13 51.1 0.0 2.2e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK20591.2 - 2.3e-08 33.6 0.0 5.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CBK20591.2 - 9.3e-08 31.8 0.0 0.0061 16.1 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CBK20591.2 - 0.0095 15.1 0.0 0.096 11.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Prok-RING_2 PF14445.1 CBK20591.2 - 0.19 11.6 3.3 0.66 9.9 2.3 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 AAA PF00004.24 CBK20592.2 - 8.6e-44 148.9 0.2 3.9e-43 146.8 0.0 2.2 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK20592.2 - 4.5e-07 30.0 0.0 2.2e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBK20592.2 - 1.4e-06 28.0 0.0 6.1e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK20592.2 - 5.7e-06 26.4 0.1 0.00029 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK20592.2 - 1.6e-05 24.8 0.1 4.3e-05 23.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBK20592.2 - 1.7e-05 25.5 0.4 0.00013 22.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK20592.2 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBK20592.2 - 0.00021 20.4 0.0 0.00039 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBK20592.2 - 0.0004 19.8 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBK20592.2 - 0.0006 18.9 0.5 0.0023 17.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin DivIC PF04977.10 CBK20592.2 - 0.0008 18.8 2.5 0.002 17.5 1.7 1.6 1 0 0 1 1 1 1 Septum formation initiator AAA_14 PF13173.1 CBK20592.2 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK20592.2 - 0.001 17.8 0.5 0.0017 17.1 0.0 1.6 2 0 0 2 2 1 1 TIP49 C-terminus AAA_33 PF13671.1 CBK20592.2 - 0.0038 17.1 0.0 0.0038 17.1 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 CBK20592.2 - 0.0045 16.9 1.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CBK20592.2 - 0.0054 15.9 0.0 0.07 12.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.7 CBK20592.2 - 0.0062 16.2 0.0 0.51 9.9 0.0 2.5 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 CBK20592.2 - 0.0067 16.7 0.1 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain TMF_DNA_bd PF12329.3 CBK20592.2 - 0.0093 15.7 3.3 0.026 14.2 2.3 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Mg_chelatase PF01078.16 CBK20592.2 - 0.011 14.9 0.1 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBK20592.2 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBK20592.2 - 0.014 15.4 0.0 0.11 12.4 0.0 2.5 2 1 1 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBK20592.2 - 0.015 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK20592.2 - 0.015 14.6 0.4 0.13 11.6 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_13 PF13166.1 CBK20592.2 - 0.02 13.3 0.4 0.82 8.0 0.7 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBK20592.2 - 0.026 14.6 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CBK20592.2 - 0.027 13.5 0.2 0.16 11.0 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.1 CBK20592.2 - 0.028 13.9 0.4 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBK20592.2 - 0.029 13.8 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CBK20592.2 - 0.038 12.8 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CBK20592.2 - 0.038 12.8 0.0 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 CBK20592.2 - 0.038 12.8 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CBK20592.2 - 0.11 12.1 0.3 1.9 8.1 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 CBK20592.2 - 0.14 12.4 0.3 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CBK20592.2 - 0.15 12.3 1.7 19 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain APG6 PF04111.7 CBK20592.2 - 0.16 10.9 1.6 0.27 10.2 1.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 CBK20592.2 - 0.27 11.6 1.7 0.64 10.5 1.2 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 CBK20593.2 - 0.00016 20.9 0.2 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBK20593.2 - 0.0085 15.9 0.6 0.042 13.6 0.5 1.9 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 CBK20593.2 - 0.012 14.5 4.4 0.019 13.9 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 CBK20593.2 - 0.012 15.1 3.4 0.022 14.3 2.4 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2730 PF10805.3 CBK20593.2 - 0.04 13.6 0.3 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF948 PF06103.6 CBK20593.2 - 0.043 13.6 4.1 2.1 8.2 0.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 CBK20593.2 - 0.045 13.3 3.3 0.12 11.9 2.3 1.7 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 CBK20593.2 - 0.051 11.9 1.7 0.087 11.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 CBK20593.2 - 0.057 11.8 2.8 0.098 11.0 1.9 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Herpes_UL49_2 PF04823.7 CBK20593.2 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Seadorna_VP6 PF07407.6 CBK20593.2 - 0.061 12.0 0.9 0.081 11.6 0.6 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Snapin_Pallidin PF14712.1 CBK20593.2 - 0.082 13.2 2.5 0.16 12.2 1.1 2.0 1 1 0 1 1 1 0 Snapin/Pallidin Syntaxin PF00804.20 CBK20593.2 - 0.12 12.5 4.1 0.36 11.0 2.8 1.8 1 0 0 1 1 1 0 Syntaxin COG5 PF10392.4 CBK20593.2 - 0.13 12.2 6.6 2.3 8.1 1.5 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 AAA_27 PF13514.1 CBK20593.2 - 0.14 9.8 1.0 0.25 8.9 0.7 1.4 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 CBK20593.2 - 0.64 9.8 7.5 1.1 9.1 2.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBK20593.2 - 1.2 8.6 5.2 11 5.6 1.0 2.6 1 1 1 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBK20593.2 - 1.4 8.7 8.8 2.3 7.9 3.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 CBK20593.2 - 2 8.8 6.9 1 9.7 2.3 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF972) Aldo_ket_red PF00248.16 CBK20594.2 - 3.7e-07 29.2 0.0 4.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TT_ORF1 PF02956.9 CBK20594.2 - 5.4 5.3 7.0 6.6 5.0 4.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 Pkinase PF00069.20 CBK20595.2 - 8.3e-67 225.0 0.0 1.5e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20595.2 - 9.5e-42 142.8 0.0 1.4e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CBK20595.2 - 4.2e-06 27.0 0.3 1.2e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CBK20595.2 - 5.4e-05 22.2 0.0 0.00051 19.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBK20595.2 - 0.0023 17.6 0.4 0.02 14.6 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBK20595.2 - 0.014 14.2 0.2 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KH_1 PF00013.24 CBK20597.2 - 1.5e-10 40.5 1.3 1.8e-10 40.2 0.9 1.1 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBK20597.2 - 1.1e-07 31.3 2.6 1.5e-07 30.9 1.8 1.2 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBK20597.2 - 0.032 13.7 0.2 0.036 13.6 0.1 1.4 1 1 0 1 1 1 0 KH domain LRR19-TM PF15176.1 CBK20598.2 - 0.0091 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Hum_adeno_E3A PF05393.6 CBK20598.2 - 0.13 11.8 0.1 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein WD40 PF00400.27 CBK20599.2 - 1e-06 28.3 1.2 0.00012 21.7 0.2 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat NTR PF01759.16 CBK20599.2 - 0.037 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Phyto_Pns9_10 PF05878.6 CBK20599.2 - 0.053 12.5 0.1 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Nup160 PF11715.3 CBK20599.2 - 0.1 10.6 0.0 0.15 10.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ribosomal_S9 PF00380.14 CBK20601.2 - 1.5e-33 115.5 0.1 1.7e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AICARFT_IMPCHas PF01808.13 CBK20603.2 - 1.3e-93 313.5 0.1 2e-93 312.9 0.1 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CBK20603.2 - 2e-26 91.7 0.0 5e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain N6-adenineMlase PF10237.4 CBK20603.2 - 0.0049 16.5 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase WD40 PF00400.27 CBK20604.2 - 3.1e-16 58.5 14.7 1.2e-06 28.1 0.4 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 CBK20604.2 - 0.064 12.6 0.0 0.22 10.9 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain tRNA-synt_2 PF00152.15 CBK20605.2 - 9.1e-69 231.7 0.0 1.5e-68 231.0 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CBK20605.2 - 0.00065 18.9 0.3 0.17 11.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UQ_con PF00179.21 CBK20606.2 - 2.1e-34 117.9 0.0 5.4e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ycf1 PF05758.7 CBK20606.2 - 0.025 12.3 11.9 0.03 12.0 8.2 1.0 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 CBK20606.2 - 0.045 12.2 19.7 0.052 12.0 13.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 CBK20606.2 - 0.6 10.1 18.8 0.96 9.4 13.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2413 PF10310.4 CBK20606.2 - 0.69 8.6 17.1 0.87 8.3 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SID-1_RNA_chan PF13965.1 CBK20606.2 - 0.76 7.8 2.4 0.89 7.6 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SPATIAL PF15256.1 CBK20606.2 - 0.82 9.6 8.8 1.2 9.1 6.1 1.2 1 0 0 1 1 1 0 SPATIAL FAM60A PF15396.1 CBK20606.2 - 1.2 8.7 10.5 1.7 8.3 7.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 CBK20606.2 - 1.6 6.3 17.0 2.1 5.9 11.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CBK20606.2 - 2 6.7 6.4 2.5 6.3 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.12 CBK20606.2 - 2.2 7.0 9.2 3 6.5 6.4 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 CBK20606.2 - 2.7 7.8 4.4 3.4 7.4 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.1 CBK20606.2 - 3.7 7.1 9.2 5 6.7 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Pox_Ag35 PF03286.9 CBK20606.2 - 4.9 6.6 21.2 7 6.1 14.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHHW PF14286.1 CBK20606.2 - 5.4 6.2 12.1 6.9 5.8 8.4 1.1 1 0 0 1 1 1 0 DHHW protein TFIIF_alpha PF05793.7 CBK20606.2 - 7.3 4.8 30.2 9.6 4.4 21.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Alpha-amylase PF00128.19 CBK20608.2 - 0.0069 15.8 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.1 CBK20608.2 - 0.024 14.6 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Amidohydro_5 PF13594.1 CBK20609.2 - 7.7e-11 41.6 1.9 4.9e-10 39.0 1.3 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CBK20609.2 - 6.3e-05 23.1 0.0 7.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBK20609.2 - 0.0018 17.9 0.1 0.0025 17.5 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBK20609.2 - 0.041 13.0 1.2 0.89 8.6 0.4 2.0 1 1 1 2 2 2 0 Amidohydrolase family XPA_C PF05181.7 CBK20609.2 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 XPA protein C-terminus Amidohydro_4 PF13147.1 CBK20610.2 - 3.6e-13 50.1 0.1 4.8e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CBK20610.2 - 1.3e-06 27.9 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 CBK20610.2 - 8.2e-06 25.6 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family ADH_zinc_N PF00107.21 CBK20611.2 - 1.5e-31 108.6 0.0 2.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBK20611.2 - 5.3e-17 62.8 0.0 3.9e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBK20611.2 - 1.1e-11 44.3 2.2 9e-11 41.5 0.1 2.7 1 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Proteasome PF00227.21 CBK20612.2 - 2.3e-52 177.0 0.1 3.1e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK20612.2 - 2.5e-15 55.4 1.1 2.9e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CofC PF01983.11 CBK20612.2 - 0.076 11.9 1.5 0.12 11.3 1.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like Abhydrolase_6 PF12697.2 CBK20613.2 - 1.6e-15 57.6 0.4 3.2e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 CBK20613.2 - 1.4e-11 43.5 0.0 3.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 CBK20613.2 - 5.2e-07 29.5 0.6 3e-06 27.0 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBK20613.2 - 0.00052 19.6 0.8 0.0061 16.1 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 CBK20613.2 - 0.0026 17.5 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 CBK20613.2 - 0.0075 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family UDPGP PF01704.13 CBK20614.2 - 6.4e-09 34.7 0.0 9.9e-09 34.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sec1 PF00995.18 CBK20615.2 - 4.5e-14 51.9 0.0 4.9e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBK20616.2 - 1.6e-42 145.9 0.1 2.7e-42 145.1 0.1 1.3 1 1 0 1 1 1 1 Sec1 family EF-hand_4 PF12763.2 CBK20618.2 - 2.2e-78 258.6 0.0 9.4e-17 60.6 0.0 5.2 5 0 0 5 5 5 5 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBK20618.2 - 4.3e-27 94.0 7.7 2.7e-05 24.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 CBK20618.2 - 7.2e-20 70.3 1.5 0.0021 17.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CBK20618.2 - 7.7e-20 68.6 12.3 0.0084 15.3 0.1 7.9 8 0 0 8 8 8 4 EF hand EF-hand_6 PF13405.1 CBK20618.2 - 1.1e-12 46.6 15.3 1.1 9.3 0.0 8.2 8 0 0 8 8 8 4 EF-hand domain End3 PF12761.2 CBK20618.2 - 1.9e-11 43.9 15.0 0.64 9.6 0.0 6.3 6 0 0 6 6 6 5 Actin cytoskeleton-regulatory complex protein END3 EF-hand_5 PF13202.1 CBK20618.2 - 1.6e-09 36.6 20.2 0.23 10.8 0.1 7.2 8 0 0 8 8 8 4 EF hand DUF2421 PF10334.4 CBK20618.2 - 3.6e-08 33.2 10.3 1.5 8.3 0.0 5.2 4 1 1 5 5 5 4 Protein of unknown function (DUF2421) MgsA_C PF12002.3 CBK20618.2 - 4.7e-06 26.3 5.9 5.6 6.6 0.0 4.3 4 0 0 4 4 4 4 MgsA AAA+ ATPase C terminal VCBS PF13517.1 CBK20618.2 - 6.3e-05 23.2 1.0 42 4.5 0.0 4.3 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Nucleoplasmin PF03066.10 CBK20618.2 - 0.0048 16.4 36.8 0.13 11.7 0.6 5.1 5 0 0 5 5 5 3 Nucleoplasmin Secretin_N PF03958.12 CBK20618.2 - 0.0076 16.4 0.5 1.4e+02 2.7 0.0 4.4 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain FG-GAP PF01839.18 CBK20618.2 - 0.057 13.1 8.4 44 3.9 0.1 4.2 4 0 0 4 4 4 0 FG-GAP repeat AAA_22 PF13401.1 CBK20618.2 - 0.21 11.7 0.0 2.5e+02 1.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain Sugar_transport PF06800.7 CBK20619.2 - 0.0049 15.9 1.8 0.0049 15.9 1.3 2.7 3 0 0 3 3 3 1 Sugar transport protein Totivirus_coat PF05518.6 CBK20619.2 - 2.6 5.7 8.9 3.4 5.3 6.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein CCT PF06203.9 CBK20620.2 - 2.9e-15 55.6 14.0 4.3e-15 55.0 9.7 1.3 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.5 CBK20620.2 - 0.00098 18.6 3.5 0.0025 17.3 2.4 1.7 1 0 0 1 1 1 1 Divergent CCT motif B56 PF01603.15 CBK20621.2 - 3.6e-112 374.9 4.0 6.9e-112 374.0 0.4 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.24 CBK20621.2 - 0.073 13.2 0.3 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 PH domain NADH_B2 PF14813.1 CBK20622.2 - 1.8e-05 24.3 2.3 2.3e-05 23.9 1.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 RRM_2 PF04059.7 CBK20623.2 - 4.5e-25 87.4 0.3 7.8e-25 86.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 WD40 PF00400.27 CBK20624.2 - 9.2e-05 22.1 0.1 0.046 13.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ PF01011.16 CBK20624.2 - 0.025 14.1 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat ESCRT-II PF05871.7 CBK20625.2 - 4.9e-28 97.7 0.0 6.2e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Git3 PF11710.3 CBK20625.2 - 0.36 10.3 5.5 0.35 10.3 2.7 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Shisa PF13908.1 CBK20626.2 - 5.5e-05 23.4 3.6 5.5e-05 23.4 2.5 2.3 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator LAT PF15234.1 CBK20626.2 - 0.0012 18.4 0.3 0.002 17.6 0.2 1.4 1 0 0 1 1 1 1 Linker for activation of T-cells 7TM_GPCR_Srd PF10317.4 CBK20626.2 - 0.0029 16.6 0.9 1.2 8.0 0.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srd Cytadhesin_P30 PF07271.6 CBK20626.2 - 0.009 15.3 7.8 0.013 14.7 5.4 1.3 1 0 0 1 1 1 1 Cytadhesin P30/P32 Trypan_PARP PF05887.6 CBK20626.2 - 0.022 14.5 0.0 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4064 PF13273.1 CBK20626.2 - 0.082 13.0 0.3 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CAMSAP_CKK PF08683.6 CBK20628.2 - 0.035 13.8 0.1 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Rab5-bind PF09311.6 CBK20628.2 - 0.046 13.6 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 Rabaptin-like protein Sod_Cu PF00080.15 CBK20629.2 - 3.2e-31 108.4 0.4 3.7e-31 108.1 0.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HSP20 PF00011.16 CBK20630.2 - 5e-10 39.1 0.0 5.3e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family UQ_con PF00179.21 CBK20631.2 - 3e-43 146.6 0.1 4.4e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK20631.2 - 0.00014 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK20631.2 - 0.13 12.1 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain ArgK PF03308.11 CBK20632.2 - 6.3e-81 271.0 0.0 1.3e-80 270.0 0.0 1.5 1 1 0 1 1 1 1 ArgK protein cobW PF02492.14 CBK20632.2 - 2.4e-08 33.6 0.1 7.7e-08 31.9 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CBK20632.2 - 7.9e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CBK20632.2 - 8.7e-06 25.2 0.0 1.7e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CBK20632.2 - 6.3e-05 22.6 0.0 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CBK20632.2 - 0.00029 20.3 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK20632.2 - 0.00034 21.4 0.1 0.00093 20.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBK20632.2 - 0.00057 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBK20632.2 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CBK20632.2 - 0.0025 18.0 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBK20632.2 - 0.0031 16.9 0.1 0.031 13.7 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 CBK20632.2 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.1 CBK20632.2 - 0.0037 17.3 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CBK20632.2 - 0.0062 15.9 0.0 0.49 9.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBK20632.2 - 0.0065 16.7 0.2 0.017 15.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 CBK20632.2 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_31 PF13614.1 CBK20632.2 - 0.0075 16.2 0.6 0.3 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 CBK20632.2 - 0.0096 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_10 PF12846.2 CBK20632.2 - 0.012 15.0 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CBK20632.2 - 0.014 15.1 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CBK20632.2 - 0.019 14.8 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_trans_4_4 PF13579.1 CBK20632.2 - 0.02 15.0 0.0 0.13 12.3 0.0 2.2 3 0 0 3 3 2 0 Glycosyl transferase 4-like domain AAA_25 PF13481.1 CBK20632.2 - 0.027 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 CBK20632.2 - 0.032 13.2 0.5 0.073 12.1 0.2 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase AAA PF00004.24 CBK20632.2 - 0.044 13.9 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CBK20632.2 - 0.048 13.9 0.1 0.08 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBK20632.2 - 0.085 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 CBK20632.2 - 0.11 12.5 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBK20632.2 - 0.12 12.5 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.5 CBK20632.2 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 CBK20632.2 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Agouti PF05039.7 CBK20633.2 - 0.12 12.7 18.3 0.45 10.9 3.0 2.2 1 1 1 2 2 2 0 Agouti protein Asp-B-Hydro_N PF05279.6 CBK20633.2 - 0.5 10.1 34.5 0.6 9.9 23.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3801 PF12687.2 CBK20633.2 - 0.6 9.6 21.7 0.79 9.2 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF3728 PF12528.3 CBK20633.2 - 1 9.8 3.2 19 5.7 0.1 2.4 1 1 1 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) CENP-T PF15511.1 CBK20633.2 - 3.1 6.9 19.6 3.8 6.6 13.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF966 PF06136.8 CBK20633.2 - 7.1 5.9 18.3 9 5.6 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RRM_1 PF00076.17 CBK20634.2 - 5.4e-24 83.6 1.4 3.1e-20 71.5 0.2 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20634.2 - 1.4e-17 63.4 0.4 1.7e-15 56.7 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20634.2 - 2.3e-10 40.1 0.1 5.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK20634.2 - 0.0001 22.0 0.0 0.00036 20.2 0.0 2.0 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Suf PF05843.9 CBK20634.2 - 0.00051 19.8 19.2 0.0036 17.0 13.3 2.0 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) Nup35_RRM PF05172.8 CBK20634.2 - 0.0075 15.9 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SOBP PF15279.1 CBK20634.2 - 2.8 8.2 5.3 4.1 7.6 3.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_S28e PF01200.13 CBK20635.2 - 5.4e-29 99.7 1.9 5.8e-29 99.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e GNT-I PF03071.10 CBK20636.2 - 4.9e-34 117.6 0.0 6.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 GNT-I family LSM PF01423.17 CBK20637.2 - 8e-13 47.7 0.0 1.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBK20637.2 - 0.041 13.8 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Mito_carr PF00153.22 CBK20638.2 - 6.3e-71 234.1 2.3 1.9e-22 78.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 CBK20639.2 - 2e-18 65.7 0.0 2.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20639.2 - 7.8e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20639.2 - 5.2e-09 35.8 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 CBK20640.2 - 7.5e-21 73.8 0.2 1.2e-20 73.1 0.2 1.3 1 0 0 1 1 1 1 Bromodomain ABC_tran PF00005.22 CBK20641.2 - 7.8e-34 116.9 0.0 1.3e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBK20641.2 - 2.7e-14 53.8 7.0 0.0089 16.0 0.0 4.5 3 2 1 5 5 4 4 AAA domain SMC_N PF02463.14 CBK20641.2 - 1.1e-13 50.9 1.8 0.00032 19.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 CBK20641.2 - 7.2e-12 44.6 3.4 7.2e-12 44.6 2.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 CBK20641.2 - 3.3e-08 32.8 3.0 3.3e-08 32.8 2.1 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.1 CBK20641.2 - 9.4e-08 31.5 0.2 0.44 9.5 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain Fer4_6 PF12837.2 CBK20641.2 - 4.3e-06 26.3 10.0 6.4e-06 25.7 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 CBK20641.2 - 1.2e-05 25.4 0.3 0.029 14.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBK20641.2 - 2.9e-05 23.4 0.1 0.12 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 CBK20641.2 - 3.1e-05 23.6 0.4 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CBK20641.2 - 4.2e-05 23.7 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 CBK20641.2 - 5.5e-05 23.4 0.2 5.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain DUF258 PF03193.11 CBK20641.2 - 8.2e-05 21.8 0.0 0.36 10.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SRP54 PF00448.17 CBK20641.2 - 0.00015 21.3 1.4 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.2 CBK20641.2 - 0.00019 21.1 1.9 0.00019 21.1 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain MobB PF03205.9 CBK20641.2 - 0.0002 21.1 0.7 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBK20641.2 - 0.00026 21.8 0.7 0.11 13.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK20641.2 - 0.00026 20.8 0.1 0.12 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 CBK20641.2 - 0.00053 20.2 2.3 0.00053 20.2 1.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_16 PF13191.1 CBK20641.2 - 0.00054 19.9 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CBK20641.2 - 0.00059 20.2 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBK20641.2 - 0.00063 20.2 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 CBK20641.2 - 0.00064 19.5 0.0 0.17 11.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 CBK20641.2 - 0.0011 18.5 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_10 PF13237.1 CBK20641.2 - 0.0012 18.5 1.7 0.0012 18.5 1.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 CBK20641.2 - 0.0015 18.6 0.0 2.7 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 CBK20641.2 - 0.002 17.7 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_16 PF13484.1 CBK20641.2 - 0.0021 18.7 0.2 0.0021 18.7 0.1 2.2 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain AAA_18 PF13238.1 CBK20641.2 - 0.0034 17.6 0.0 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBK20641.2 - 0.005 15.5 0.1 0.073 11.7 0.1 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 CBK20641.2 - 0.0058 16.4 11.4 0.019 14.8 8.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CBK20641.2 - 0.0078 15.6 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBK20641.2 - 0.012 15.3 0.6 1 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_3 PF12798.2 CBK20641.2 - 0.013 16.0 4.7 0.013 16.0 3.2 2.2 2 0 0 2 2 1 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 CBK20641.2 - 0.018 14.3 0.1 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase DUF815 PF05673.8 CBK20641.2 - 0.02 13.8 0.2 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBK20641.2 - 0.022 14.7 1.7 1.9 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Fer4_15 PF13459.1 CBK20641.2 - 0.023 15.2 0.6 0.073 13.6 0.5 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain AAA_30 PF13604.1 CBK20641.2 - 0.027 14.0 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CBK20641.2 - 0.035 12.7 0.2 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 CBK20641.2 - 0.036 13.9 0.1 5.6 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CBK20641.2 - 0.036 14.4 2.5 0.036 14.4 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.10 CBK20641.2 - 0.076 12.7 1.2 10 5.8 0.0 3.1 3 0 0 3 3 2 0 NTPase Arch_ATPase PF01637.13 CBK20641.2 - 0.091 12.4 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 CBK20641.2 - 0.12 11.1 0.1 6.8 5.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CBK20641.2 - 0.13 11.7 0.8 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF359 PF04019.7 CBK20641.2 - 0.14 11.5 0.2 0.39 10.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF359) AAA_24 PF13479.1 CBK20641.2 - 0.14 11.6 0.3 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK20641.2 - 0.17 10.7 0.4 0.84 8.4 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_13 PF13166.1 CBK20641.2 - 0.25 9.7 0.8 0.53 8.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.1 CBK20641.2 - 0.55 10.3 8.4 0.097 12.7 1.0 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK20641.2 - 3.4 8.1 8.8 0.49 10.8 2.9 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain EMG1 PF03587.9 CBK20642.2 - 1.4e-58 197.5 0.0 1.5e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MoeZ_MoeB PF05237.8 CBK20643.2 - 0.0013 18.2 0.6 0.0026 17.3 0.4 1.6 1 1 0 1 1 1 1 MoeZ/MoeB domain Fer4_11 PF13247.1 CBK20643.2 - 0.12 12.3 0.1 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain ThiF PF00899.16 CBK20644.2 - 1.9e-27 95.7 0.0 2.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.14 CBK20644.2 - 0.00024 20.2 0.0 0.00028 20.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CBK20644.2 - 0.00029 20.2 0.0 0.00035 20.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CBK20644.2 - 0.0052 16.5 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CBK20644.2 - 0.0052 16.8 0.0 0.0088 16.1 0.0 1.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CBK20644.2 - 0.0064 15.5 0.2 0.0079 15.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Ldh_1_N PF00056.18 CBK20644.2 - 0.014 15.2 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 CBK20644.2 - 0.026 14.1 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HHH_5 PF14520.1 CBK20644.2 - 0.041 14.0 0.0 0.075 13.2 0.0 1.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain ApbA PF02558.11 CBK20644.2 - 0.069 12.5 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 CBK20644.2 - 0.089 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 CBK20644.2 - 0.092 11.7 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 CBK20644.2 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 CBK20644.2 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF647 PF04884.9 CBK20645.2 - 1.9e-28 99.3 0.6 2.6e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MORN PF02493.15 CBK20647.2 - 0.0007 19.1 21.5 0.11 12.2 1.0 7.3 6 0 0 6 6 6 2 MORN repeat MORN PF02493.15 CBK20648.2 - 9.3e-10 37.6 41.9 0.0033 17.0 0.6 8.0 9 0 0 9 9 9 5 MORN repeat ABC_tran PF00005.22 CBK20649.2 - 1.7e-31 109.3 0.0 3.3e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CBK20649.2 - 5.9e-07 29.7 1.5 0.0075 16.2 0.5 2.3 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBK20649.2 - 0.00017 20.9 0.4 0.19 10.9 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBK20649.2 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK20649.2 - 0.00052 19.4 0.1 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBK20649.2 - 0.0021 18.0 0.5 0.004 17.1 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 CBK20649.2 - 0.0047 16.8 0.4 0.065 13.1 0.3 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CBK20649.2 - 0.011 15.6 0.1 0.031 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CBK20649.2 - 0.013 15.4 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 CBK20649.2 - 0.017 14.5 0.2 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBK20649.2 - 0.023 15.2 0.1 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CBK20649.2 - 0.028 14.7 0.1 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBK20649.2 - 0.034 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CBK20649.2 - 0.049 14.4 0.1 0.1 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBK20649.2 - 0.061 13.4 0.3 0.12 12.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBK20649.2 - 0.071 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBK20649.2 - 0.078 13.2 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CBK20649.2 - 0.1 11.6 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 CBK20649.2 - 0.14 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 CBK20649.2 - 0.15 11.7 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CBK20649.2 - 0.17 11.5 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CBK20649.2 - 0.27 11.0 1.8 0.27 11.0 0.4 1.6 2 0 0 2 2 2 0 Dynamin family Ribosomal_L10 PF00466.15 CBK20650.2 - 1.1e-21 76.6 0.2 2.8e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 Mito_carr PF00153.22 CBK20650.2 - 9.7e-20 70.0 0.1 7.8e-10 38.3 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_60s PF00428.14 CBK20650.2 - 2.7e-12 46.8 7.2 6.3e-12 45.7 5.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein WD40 PF00400.27 CBK20651.2 - 4.7e-31 105.5 1.4 8.3e-11 41.3 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 CBK20651.2 - 3.3e-05 23.6 0.1 0.034 13.8 0.0 2.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBK20651.2 - 0.092 10.8 1.0 0.13 10.3 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 BSP_II PF05432.6 CBK20651.2 - 0.12 11.6 13.4 0.18 11.0 9.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med17 PF10156.4 CBK20651.2 - 0.2 9.8 3.6 0.24 9.6 2.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RRN3 PF05327.6 CBK20651.2 - 0.5 8.4 4.8 0.61 8.1 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 CBK20651.2 - 0.56 9.4 12.4 0.73 9.0 8.6 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 CBK20651.2 - 1.6 8.3 6.6 1.6 8.3 3.9 1.5 2 0 0 2 2 2 0 FAM176 family VID27 PF08553.5 CBK20651.2 - 6 4.9 14.1 13 3.8 9.9 1.4 1 1 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 CBK20651.2 - 6.3 5.8 11.0 8.9 5.3 7.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PI3K_1B_p101 PF10486.4 CBK20651.2 - 6.5 4.1 6.0 8 3.8 4.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ribosomal_60s PF00428.14 CBK20651.2 - 7 7.1 16.3 15 6.0 11.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 CBK20651.2 - 7.9 5.3 8.4 10 5.0 5.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SIR2 PF02146.12 CBK20652.2 - 8.5e-54 181.9 0.0 1e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family MORN PF02493.15 CBK20654.2 - 8.4e-10 37.7 11.3 0.00019 20.9 0.1 3.7 3 0 0 3 3 3 3 MORN repeat MORN_2 PF07661.8 CBK20654.2 - 0.031 14.2 7.7 0.17 11.9 0.3 3.1 3 0 0 3 3 3 0 MORN repeat variant Guanylate_cyc_2 PF09778.4 CBK20655.2 - 2.6e-18 66.0 2.0 4.3e-18 65.3 1.4 1.3 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.1 CBK20655.2 - 0.0012 19.2 0.0 0.01 16.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase_C39 like family RRM_5 PF13893.1 CBK20656.2 - 2.2e-11 43.4 0.0 2.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK20656.2 - 1.2e-10 40.8 0.0 1.9e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20656.2 - 1.8e-06 27.8 0.0 3.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CHORD PF04968.7 CBK20657.2 - 4.3e-50 167.8 32.0 2.4e-25 88.5 7.6 2.5 2 1 1 3 3 3 2 CHORD DEC-1_N PF04625.8 CBK20657.2 - 1.2 7.7 12.5 1.5 7.4 8.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retinal PF15449.1 CBK20657.2 - 6.8 4.2 11.9 8.3 3.9 8.2 1.0 1 0 0 1 1 1 0 Retinal protein FAP PF07174.6 CBK20657.2 - 9.2 5.4 20.7 12 5.0 14.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ank_2 PF12796.2 CBK20658.2 - 1.5e-11 44.4 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBK20658.2 - 1.7e-11 43.2 0.0 5e-10 38.6 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBK20658.2 - 5.3e-11 42.7 0.3 8.5e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBK20658.2 - 5.7e-11 42.2 0.5 1.3e-10 41.1 0.1 1.9 2 1 0 2 2 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK20658.2 - 3e-08 33.1 0.0 1.2e-06 28.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat TPR_1 PF00515.23 CBK20658.2 - 0.0003 20.2 0.5 0.0031 17.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20658.2 - 0.0021 17.8 1.8 0.015 15.1 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20658.2 - 0.0025 17.6 0.0 0.0076 16.1 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK20658.2 - 0.0029 17.2 0.1 0.046 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK20658.2 - 0.023 14.3 0.0 0.081 12.5 0.0 1.9 1 0 0 1 1 1 0 TPR repeat DUF2385 PF09539.5 CBK20658.2 - 0.047 14.0 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Cytochrom_B562 PF07361.6 CBK20658.2 - 0.051 13.9 0.9 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome b562 TPR_8 PF13181.1 CBK20658.2 - 0.11 12.3 0.2 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SRX PF09201.5 CBK20658.2 - 0.11 12.1 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 SRX zf-TRM13_CCCH PF11722.3 CBK20658.2 - 0.12 11.7 1.8 0.35 10.2 0.3 2.3 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein PPR PF01535.15 CBK20658.2 - 0.33 11.0 2.1 4 7.6 0.1 3.4 4 0 0 4 4 4 0 PPR repeat PurS PF02700.9 CBK20659.2 - 0.018 14.9 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Swi3 PF07962.7 CBK20660.2 - 0.087 12.4 0.1 0.092 12.3 0.0 1.0 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 MMS1_N PF10433.4 CBK20661.2 - 2e-06 26.2 0.1 3.1e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 CBK20662.2 - 4.4e-12 45.7 0.0 4.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Sigma70_r4 PF04545.11 CBK20662.2 - 0.03 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2281 PF10047.4 CBK20663.2 - 0.15 12.3 1.4 0.41 10.9 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) HLH PF00010.21 CBK20664.2 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain HSP70 PF00012.15 CBK20665.2 - 7e-243 806.9 20.1 6.8e-195 648.4 2.0 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK20665.2 - 1.2e-19 70.0 1.7 8.9e-18 63.9 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CBK20665.2 - 0.0009 18.4 7.0 0.004 16.2 0.1 3.1 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CBK20665.2 - 0.0011 18.6 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain plasmid_Toxin PF12703.2 CBK20665.2 - 0.05 13.4 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system FtsA PF14450.1 CBK20665.2 - 0.083 12.7 5.9 17 5.2 4.1 3.8 1 1 0 1 1 1 0 Cell division protein FtsA LRR_8 PF13855.1 CBK20666.2 - 1.1e-07 31.5 3.4 0.00047 19.8 0.3 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK20666.2 - 0.0022 17.5 6.5 3.2 7.4 1.2 5.0 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) MIF4G PF02854.14 CBK20667.2 - 8.6e-14 51.4 2.8 8.6e-14 51.4 1.9 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBK20667.2 - 5.5e-13 48.5 0.5 1.7e-12 47.0 0.3 1.9 1 0 0 1 1 1 1 MA3 domain Ferritin PF00210.19 CBK20667.2 - 0.023 14.4 0.1 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Ferritin-like domain YCII PF03795.9 CBK20668.2 - 9e-09 35.4 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Tom7 PF08038.7 CBK20669.2 - 6.5e-10 38.3 0.5 7.1e-10 38.1 0.3 1.2 1 0 0 1 1 1 1 TOM7 family Nup54 PF13874.1 CBK20670.2 - 0.0083 15.7 15.9 0.011 15.3 11.0 1.2 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF3584 PF12128.3 CBK20670.2 - 0.013 12.8 15.8 0.016 12.5 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-Q PF13094.1 CBK20670.2 - 0.015 15.2 25.0 0.025 14.5 17.3 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TelA PF05816.6 CBK20670.2 - 0.019 13.6 8.5 0.024 13.3 5.9 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) EMP24_GP25L PF01105.19 CBK20670.2 - 0.02 14.6 7.4 0.02 14.6 5.1 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Hemerythrin PF01814.18 CBK20670.2 - 0.02 15.0 5.1 0.028 14.5 3.5 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Nup88 PF10168.4 CBK20670.2 - 0.024 12.5 15.1 0.027 12.3 10.5 1.1 1 0 0 1 1 1 0 Nuclear pore component GOLGA2L5 PF15070.1 CBK20670.2 - 0.024 13.1 17.4 0.026 13.0 12.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 CENP-K PF11802.3 CBK20670.2 - 0.029 13.6 11.9 0.034 13.3 8.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K ISG65-75 PF11727.3 CBK20670.2 - 0.029 13.4 10.3 0.038 13.0 7.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3417 PF11897.3 CBK20670.2 - 0.039 13.9 0.9 0.039 13.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) Spc7 PF08317.6 CBK20670.2 - 0.043 12.4 16.8 0.046 12.3 11.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 CBK20670.2 - 0.061 12.2 17.9 0.071 12.0 12.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CBK20670.2 - 0.11 11.5 20.8 0.12 11.3 14.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Z1 PF10593.4 CBK20670.2 - 0.11 11.6 5.7 0.13 11.4 4.0 1.1 1 0 0 1 1 1 0 Z1 domain Rab5-bind PF09311.6 CBK20670.2 - 0.13 12.1 25.1 0.17 11.7 17.4 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF2381 PF09544.5 CBK20670.2 - 0.14 11.2 2.3 0.14 11.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Tropomyosin PF00261.15 CBK20670.2 - 0.15 11.0 23.1 0.21 10.6 16.0 1.1 1 0 0 1 1 1 0 Tropomyosin AAA_32 PF13654.1 CBK20670.2 - 0.29 9.7 12.7 0.31 9.6 8.8 1.0 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 CBK20670.2 - 0.3 9.9 11.5 0.35 9.6 8.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain TBPIP PF07106.8 CBK20670.2 - 0.34 10.4 17.4 0.41 10.1 12.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4404 PF14357.1 CBK20670.2 - 0.39 11.1 16.0 0.12 12.8 8.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ParB PF08775.5 CBK20670.2 - 0.46 10.8 11.2 0.093 13.0 2.5 2.0 1 1 1 2 2 2 0 ParB family RRN3 PF05327.6 CBK20670.2 - 0.51 8.3 11.3 0.57 8.2 7.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HemX PF04375.9 CBK20670.2 - 0.52 8.8 6.9 0.57 8.7 4.8 1.2 1 0 0 1 1 1 0 HemX Laminin_II PF06009.7 CBK20670.2 - 0.71 9.6 10.5 0.98 9.1 7.3 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.3 CBK20670.2 - 0.71 9.0 14.3 0.87 8.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PDDEXK_2 PF12784.2 CBK20670.2 - 0.73 8.9 10.0 1 8.4 6.9 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase BLOC1_2 PF10046.4 CBK20670.2 - 0.73 10.0 13.6 2.7 8.1 3.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RE_Alw26IDE PF09665.5 CBK20670.2 - 0.75 8.4 11.4 0.87 8.2 7.9 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) ATP11 PF06644.6 CBK20670.2 - 0.81 9.1 9.3 0.89 9.0 6.4 1.1 1 0 0 1 1 1 0 ATP11 protein DUF812 PF05667.6 CBK20670.2 - 0.83 8.0 16.8 1 7.7 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF342 PF03961.8 CBK20670.2 - 0.85 7.9 15.0 0.89 7.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CBK20670.2 - 0.95 7.2 13.7 1.1 7.0 9.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDRGK PF09756.4 CBK20670.2 - 0.96 8.8 18.6 1.1 8.6 12.9 1.1 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.1 CBK20670.2 - 0.97 9.1 10.4 1.2 8.8 7.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.5 CBK20670.2 - 1 9.3 12.5 1.3 8.9 8.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fib_alpha PF08702.5 CBK20670.2 - 1 9.4 12.4 1.2 9.2 8.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BID PF06393.6 CBK20670.2 - 1.1 8.5 8.4 1.5 8.1 5.8 1.1 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF2203 PF09969.4 CBK20670.2 - 1.2 9.3 8.5 2.2 8.5 5.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) zf-CpG_bind_C PF12269.3 CBK20670.2 - 1.2 8.5 9.8 1.4 8.3 6.8 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain HlyD PF00529.15 CBK20670.2 - 1.2 8.3 9.0 1.3 8.2 6.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein eIF-4B PF06273.6 CBK20670.2 - 1.3 7.7 13.6 1.4 7.6 9.4 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B HAUS6_N PF14661.1 CBK20670.2 - 1.5 8.1 13.1 2.1 7.6 9.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 CBK20670.2 - 1.5 8.8 16.9 1.5 8.8 11.2 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.13 CBK20670.2 - 1.6 7.7 8.6 0.83 8.6 0.5 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ToxN_toxin PF13958.1 CBK20670.2 - 1.6 8.4 7.0 0.66 9.6 3.1 1.7 1 1 1 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system EzrA PF06160.7 CBK20670.2 - 1.7 6.7 16.9 3.7 5.5 11.8 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMPIT PF07851.8 CBK20670.2 - 1.8 7.5 12.4 2.1 7.3 8.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ycf1 PF05758.7 CBK20670.2 - 2 6.0 13.1 2.3 5.8 9.1 1.0 1 0 0 1 1 1 0 Ycf1 UvrD_C PF13361.1 CBK20670.2 - 2 7.7 9.4 2.3 7.5 6.5 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CDC37_N PF03234.9 CBK20670.2 - 2.1 8.6 16.8 2.5 8.4 11.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Bud13 PF09736.4 CBK20670.2 - 2.4 8.4 12.0 2.8 8.1 8.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex LemA PF04011.7 CBK20670.2 - 2.4 7.2 8.4 3.2 6.8 5.8 1.1 1 0 0 1 1 1 0 LemA family FDF PF09532.5 CBK20670.2 - 3 8.4 8.5 7.1 7.2 5.9 1.7 1 1 0 1 1 1 0 FDF domain OmpH PF03938.9 CBK20670.2 - 3.5 7.5 18.0 4.8 7.0 12.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IBR PF01485.16 CBK20670.2 - 3.6 7.5 6.7 6.3 6.7 4.6 1.8 1 1 0 1 1 1 0 IBR domain DUF1664 PF07889.7 CBK20670.2 - 3.7 7.3 11.4 6.3 6.6 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PA26 PF04636.8 CBK20670.2 - 3.8 6.0 9.3 3.8 6.1 6.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF972 PF06156.8 CBK20670.2 - 4.5 7.6 23.1 28 5.1 16.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Potyvirid-P3 PF13608.1 CBK20670.2 - 4.6 6.2 13.3 5.9 5.9 9.2 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Rootletin PF15035.1 CBK20670.2 - 4.9 7.0 23.7 0.93 9.4 9.8 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_GPO PF05929.6 CBK20670.2 - 6.1 6.0 10.2 7.3 5.7 7.1 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3482 PF11981.3 CBK20670.2 - 6.4 5.9 9.8 11 5.1 6.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) YscO PF07321.7 CBK20670.2 - 6.5 6.5 24.8 3.9 7.2 16.2 1.4 1 1 0 1 1 1 0 Type III secretion protein YscO Exonuc_VII_L PF02601.10 CBK20670.2 - 6.7 5.8 11.1 9.2 5.3 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mnd1 PF03962.10 CBK20670.2 - 7.6 6.1 20.3 15 5.2 14.1 1.5 1 1 0 1 1 1 0 Mnd1 family SidE PF12252.3 CBK20670.2 - 7.6 3.6 9.7 8.3 3.5 6.8 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein DUF2317 PF10079.4 CBK20670.2 - 9.8 4.6 15.6 11 4.5 10.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PPDK_N PF01326.14 CBK20671.2 - 1.1e-78 264.5 0.0 1.4e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 CBK20672.2 - 3.9e-22 77.6 0.1 7.2e-22 76.7 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GYD PF08734.6 CBK20672.2 - 0.02 14.6 0.0 0.061 13.0 0.0 1.8 1 0 0 1 1 1 0 GYD domain MAM1 PF10434.4 CBK20672.2 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Monopolin complex protein MAM1 DUF563 PF04577.9 CBK20673.2 - 3.6e-13 49.9 0.0 5.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) UBA_4 PF14555.1 CBK20674.2 - 5.2e-15 54.7 0.2 9.3e-15 53.8 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 CBK20674.2 - 0.054 13.3 0.3 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain CUE PF02845.11 CBK20674.2 - 0.084 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CUE domain Rhodanese PF00581.15 CBK20675.2 - 2.4e-09 37.5 0.0 3.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF1381 PF07129.6 CBK20675.2 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) HA2 PF04408.18 CBK20676.2 - 5.7e-14 51.9 0.0 3.3e-13 49.5 0.0 2.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBK20676.2 - 5.5e-12 45.3 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK20676.2 - 2e-07 30.6 0.9 1.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CBK20676.2 - 1e-06 28.5 0.0 3.5e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CBK20676.2 - 1.9e-05 24.7 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK20676.2 - 0.0018 17.2 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CBK20676.2 - 0.0077 15.3 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.1 CBK20676.2 - 0.45 10.8 0.0 0.45 10.8 0.0 4.3 3 1 0 3 3 3 0 AAA domain Galactosyl_T PF01762.16 CBK20677.2 - 5.3e-35 120.7 0.0 7.3e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase NAS PF03059.11 CBK20677.2 - 0.054 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein DAGK_cat PF00781.19 CBK20678.2 - 2.3e-19 69.1 0.0 3.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Phage_base_V PF04717.7 CBK20678.2 - 0.091 12.7 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Phage-related baseplate assembly protein DUF4379 PF14311.1 CBK20679.2 - 4.1e-52 173.8 42.0 3.1e-19 68.5 3.5 6.0 6 1 0 6 6 6 5 Domain of unknown function (DUF4379) Cys_rich_KTR PF14205.1 CBK20679.2 - 0.33 10.4 5.6 3.7 7.0 0.1 3.7 3 0 0 3 3 3 0 Cysteine-rich KTR HMG_box PF00505.14 CBK20680.2 - 0.028 14.6 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.5 CBK20680.2 - 0.11 12.8 0.6 0.26 11.6 0.4 1.7 1 1 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 CBK20681.2 - 1.4e-12 47.7 2.3 1.6e-12 47.5 1.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBK20681.2 - 7.7e-10 38.9 4.5 9e-10 38.7 3.1 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CBK20681.2 - 0.038 13.7 2.5 0.045 13.5 1.4 1.3 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF2740 PF10872.3 CBK20681.2 - 0.076 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Plus-3 PF03126.13 CBK20681.2 - 0.11 12.5 0.8 0.14 12.2 0.5 1.3 1 1 0 1 1 1 0 Plus-3 domain Bromo_MP PF01573.11 CBK20682.2 - 0.081 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Bromovirus movement protein dCMP_cyt_deam_1 PF00383.17 CBK20683.2 - 2.4e-09 36.7 0.1 3.8e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Fer4_10 PF13237.1 CBK20683.2 - 0.56 10.0 3.7 0.55 10.0 1.0 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF1980 PF09323.5 CBK20684.2 - 0.076 12.7 0.1 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ribosomal_L13e PF01294.13 CBK20685.2 - 1.7e-34 118.8 0.3 1.3e-33 115.9 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L13e AAA PF00004.24 CBK20686.2 - 1.4e-42 145.0 0.0 2.5e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK20686.2 - 6.1e-07 29.6 0.2 8.4e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK20686.2 - 1.6e-06 27.8 1.1 0.00011 21.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBK20686.2 - 3.9e-06 26.8 0.3 1.9e-05 24.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CBK20686.2 - 0.00012 21.0 0.0 0.0003 19.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBK20686.2 - 0.00019 21.4 0.0 0.00049 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 CBK20686.2 - 0.00037 19.4 0.1 0.044 12.6 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.1 CBK20686.2 - 0.0011 19.3 0.2 0.0067 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBK20686.2 - 0.0015 18.6 0.0 0.0048 17.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase KaiC PF06745.8 CBK20686.2 - 0.0024 17.0 0.3 0.26 10.3 0.0 2.5 1 1 1 2 2 2 1 KaiC RuvB_N PF05496.7 CBK20686.2 - 0.0029 16.7 0.0 0.0074 15.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBK20686.2 - 0.0039 16.6 1.6 0.23 10.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBK20686.2 - 0.0083 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBK20686.2 - 0.0091 15.7 0.3 0.026 14.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBK20686.2 - 0.0097 15.7 0.1 0.078 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK20686.2 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 CBK20686.2 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 CBK20686.2 - 0.012 14.3 0.0 0.025 13.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CBK20686.2 - 0.015 14.9 0.0 0.039 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBK20686.2 - 0.017 15.9 1.3 0.053 14.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 CBK20686.2 - 0.018 14.6 0.7 0.11 12.1 0.1 2.4 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.21 CBK20686.2 - 0.03 13.7 0.2 0.13 11.7 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CBK20686.2 - 0.041 13.0 0.1 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 CBK20686.2 - 0.049 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBK20686.2 - 0.051 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBK20686.2 - 0.068 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBK20686.2 - 0.068 13.1 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 CBK20686.2 - 0.095 11.6 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1129 PF06570.6 CBK20687.2 - 0.0046 16.2 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF4231 PF14015.1 CBK20687.2 - 0.074 13.0 1.6 0.11 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3611 PF12263.3 CBK20687.2 - 0.15 11.4 1.5 0.27 10.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) CKS PF01111.14 CBK20688.2 - 8e-36 121.7 0.2 1e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DENN PF02141.16 CBK20689.2 - 0.11 12.1 1.6 0.26 10.9 0.6 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain ArfGap PF01412.13 CBK20691.2 - 4.2e-24 84.5 0.4 8.1e-24 83.6 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf WD40 PF00400.27 CBK20692.2 - 1.2e-10 40.8 3.9 0.0028 17.4 0.3 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBK20692.2 - 0.0087 14.8 0.1 0.0087 14.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Apc4_WD40 PF12894.2 CBK20693.2 - 8.9e-05 21.9 0.0 0.00026 20.4 0.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Kri1_C PF12936.2 CBK20694.2 - 2e-29 101.3 1.8 2e-29 101.3 1.3 2.9 1 1 1 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.7 CBK20694.2 - 8.7e-09 35.5 7.8 8.7e-09 35.5 5.4 3.4 2 1 1 3 3 3 1 KRI1-like family DUF3799 PF12684.2 CBK20695.2 - 0.049 12.9 2.9 0.065 12.5 2.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) HD_assoc PF13286.1 CBK20695.2 - 0.053 13.8 0.2 0.053 13.8 0.1 1.7 2 0 0 2 2 2 0 Phosphohydrolase-associated domain HSP90 PF00183.13 CBK20696.2 - 2.1e-180 600.6 66.0 2.1e-180 600.6 45.7 3.1 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.21 CBK20696.2 - 7e-10 38.6 0.2 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK20696.2 - 2e-09 37.1 0.1 2e-09 37.1 0.1 3.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.5 CBK20696.2 - 0.0021 16.5 5.4 0.0037 15.7 2.0 2.1 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup UvrD_C PF13361.1 CBK20697.2 - 1.3e-09 38.0 3.3 1.8e-09 37.5 2.3 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1160 PF06648.6 CBK20697.2 - 0.56 9.9 3.5 0.96 9.2 0.4 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1160) PDDEXK_1 PF12705.2 CBK20698.2 - 1.6e-14 53.9 0.1 2.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Exo5 PF09810.4 CBK20698.2 - 0.0055 15.9 5.1 0.02 14.1 3.3 2.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Cas_Cas4 PF01930.12 CBK20698.2 - 0.0085 16.0 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF83 BOP1NT PF08145.7 CBK20698.2 - 0.039 13.6 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 BOP1NT (NUC169) domain UBN2 PF14223.1 CBK20698.2 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HSP90 PF00183.13 CBK20700.2 - 1.2e-230 766.4 32.9 1.6e-230 766.0 22.8 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CBK20700.2 - 1.1e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK20700.2 - 1.4e-11 44.2 0.1 4.8e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pfg27 PF09216.5 CBK20701.2 - 0.021 14.4 0.3 0.048 13.2 0.2 1.6 1 0 0 1 1 1 0 Pfg27 ABC_tran PF00005.22 CBK20702.2 - 1.4e-45 154.9 0.0 1.3e-26 93.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK20702.2 - 2.2e-40 138.8 24.5 1.4e-25 90.2 9.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBK20702.2 - 2.1e-08 33.6 2.4 0.0013 17.9 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBK20702.2 - 4.5e-05 22.9 0.2 0.14 11.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBK20702.2 - 7.4e-05 22.1 0.3 0.095 12.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK20702.2 - 0.00011 23.0 0.7 0.75 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CBK20702.2 - 0.00015 21.3 0.2 0.63 9.4 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 CBK20702.2 - 0.00016 21.7 0.1 0.7 9.8 0.0 4.0 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 CBK20702.2 - 0.00022 21.6 1.7 0.086 13.3 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 CBK20702.2 - 0.00026 20.8 5.2 0.21 11.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CBK20702.2 - 0.00043 20.2 1.8 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 CBK20702.2 - 0.00068 18.6 0.0 0.16 10.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 CBK20702.2 - 0.00081 19.2 0.5 0.053 13.3 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_30 PF13604.1 CBK20702.2 - 0.0019 17.8 1.6 2.1 7.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CBK20702.2 - 0.0019 17.3 0.4 0.4 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBK20702.2 - 0.0036 16.4 1.0 0.19 10.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 CBK20702.2 - 0.004 16.8 2.9 0.15 11.7 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CBK20702.2 - 0.0046 16.5 0.3 0.026 14.1 0.1 2.3 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CBK20702.2 - 0.0049 17.0 2.8 4.8 7.3 0.1 4.3 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 CBK20702.2 - 0.0062 15.9 0.6 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CBK20702.2 - 0.0065 16.0 3.9 0.68 9.4 0.9 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.24 CBK20702.2 - 0.01 16.0 1.4 2.5 8.2 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK20702.2 - 0.017 15.1 6.6 0.046 13.6 0.1 3.7 4 1 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 CBK20702.2 - 0.022 15.0 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK20702.2 - 0.025 14.0 6.6 8.8 5.6 0.1 3.4 3 0 0 3 3 3 0 AAA-like domain DUF3040 PF11239.3 CBK20702.2 - 0.037 14.0 5.0 0.65 10.0 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DnaB_C PF03796.10 CBK20702.2 - 0.045 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.1 CBK20702.2 - 0.059 13.1 5.5 0.69 9.7 0.2 4.1 3 0 0 3 3 3 0 Part of AAA domain NACHT PF05729.7 CBK20702.2 - 0.085 12.5 2.5 0.96 9.0 0.0 3.1 3 0 0 3 3 3 0 NACHT domain ResIII PF04851.10 CBK20702.2 - 0.11 12.2 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ArgK PF03308.11 CBK20702.2 - 0.2 10.3 2.2 5.9 5.5 0.1 2.2 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 CBK20702.2 - 0.25 11.1 1.1 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBK20702.2 - 0.28 11.3 1.0 50 4.1 0.0 3.2 3 0 0 3 3 3 0 RNA helicase DUF2207 PF09972.4 CBK20702.2 - 1.9 6.9 4.5 2.6 6.5 1.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NB-ARC PF00931.17 CBK20702.2 - 4.1 6.1 5.3 8.1 5.1 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain Pkinase PF00069.20 CBK20703.2 - 1.8e-46 158.4 0.0 2.3e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20703.2 - 1e-33 116.5 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20703.2 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ovate PF04844.8 CBK20703.2 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional repressor, ovate ENTH PF01417.15 CBK20704.2 - 3e-13 49.7 0.0 3.9e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.11 CBK20704.2 - 0.00036 19.3 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 ANTH domain VHS PF00790.14 CBK20704.2 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 VHS domain DUF764 PF05561.6 CBK20704.2 - 0.0048 16.3 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF764) HEAT PF02985.17 CBK20704.2 - 0.013 15.5 0.0 0.06 13.4 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat Adaptin_N PF01602.15 CBK20704.2 - 0.022 13.1 0.1 1.6 6.9 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.1 CBK20704.2 - 0.072 13.3 0.0 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats PC_rep PF01851.17 CBK20705.2 - 2.8e-07 30.3 9.2 0.007 16.5 0.2 4.7 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Apc3 PF12895.2 CBK20705.2 - 0.0084 16.2 4.2 0.21 11.7 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.1 CBK20706.2 - 7.4e-08 32.5 0.1 1.3e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 CBK20706.2 - 4.4e-05 23.2 0.1 1.7 8.9 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 CBK20706.2 - 0.036 14.5 5.5 1.2 9.6 0.3 3.4 2 1 0 3 3 3 0 HEAT-like repeat DUF2910 PF11139.3 CBK20706.2 - 0.049 12.7 0.1 0.065 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) CBFNT PF08143.6 CBK20706.2 - 2 9.5 23.8 0.15 13.1 5.4 2.7 2 0 0 2 2 2 0 CBFNT (NUC161) domain RRM_1 PF00076.17 CBK20708.2 - 1.5e-07 30.9 0.0 0.00014 21.4 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20708.2 - 7.7e-07 28.9 0.0 5.4e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20708.2 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2890 PF11081.3 CBK20708.2 - 0.016 15.2 7.0 0.021 14.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RXT2_N PF08595.6 CBK20708.2 - 0.055 13.2 3.3 0.1 12.3 2.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 CBK20708.2 - 0.73 9.5 5.3 1.4 8.5 3.7 1.4 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 CBK20708.2 - 0.81 8.2 7.7 1.1 7.7 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Metallophos PF00149.23 CBK20709.2 - 3.1e-20 72.4 0.0 4.5e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3142 PF11340.3 CBK20709.2 - 0.13 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) UPF0081 PF03652.10 CBK20710.2 - 8.1e-25 87.5 0.0 9.5e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) TAXi_C PF14541.1 CBK20711.2 - 3.4e-19 68.9 0.0 9.1e-19 67.5 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.18 CBK20711.2 - 3.2e-08 33.1 0.0 4.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBK20711.2 - 0.025 14.5 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal CBS PF00571.23 CBK20712.2 - 2.5e-31 107.2 0.2 1.2e-10 40.9 0.0 3.2 3 0 0 3 3 3 3 CBS domain Complex1_LYR_1 PF13232.1 CBK20713.2 - 0.00052 20.1 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBK20713.2 - 0.00056 19.6 0.4 0.00091 18.9 0.0 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) UFD1 PF03152.9 CBK20714.2 - 1e-48 164.8 0.0 1.2e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CBK20714.2 - 2e-06 27.3 0.2 9.9e-06 25.1 0.1 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 eIF-1a PF01176.14 CBK20714.2 - 0.062 12.7 0.4 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 DUF4134 PF13572.1 CBK20715.2 - 0.013 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) COX7B PF05392.6 CBK20716.2 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Fibrillarin PF01269.12 CBK20717.2 - 1.7e-108 360.8 0.0 2e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBK20717.2 - 1.3e-05 24.8 0.1 2.8e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBK20717.2 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) XPG_I PF00867.13 CBK20718.2 - 2.6e-22 78.6 0.0 4.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBK20718.2 - 0.00021 21.4 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain TPR_1 PF00515.23 CBK20718.2 - 0.0043 16.6 0.1 0.0078 15.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF846 PF05832.7 CBK20719.2 - 4.6e-42 143.0 12.0 5.9e-42 142.7 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Bud13 PF09736.4 CBK20720.2 - 1.3e-29 103.3 14.3 7.8e-29 100.8 9.9 1.9 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Peptidase_S46 PF10459.4 CBK20720.2 - 0.11 10.9 5.5 0.13 10.6 3.8 1.1 1 0 0 1 1 1 0 Peptidase S46 Arg_repressor PF01316.16 CBK20720.2 - 2.3 7.8 6.0 2.3 7.8 0.3 2.9 2 1 0 3 3 3 0 Arginine repressor, DNA binding domain DUF334 PF03904.8 CBK20720.2 - 4.6 6.5 8.0 6 6.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ThiF PF00899.16 CBK20722.2 - 7.4e-52 174.7 2.1 1.3e-34 118.9 0.0 3.1 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 CBK20722.2 - 7.7e-29 99.0 4.7 7.2e-24 83.1 0.5 2.9 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CBK20722.2 - 5.3e-19 68.6 0.0 9.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CBK20722.2 - 1.3e-13 50.1 0.5 8.4e-11 41.0 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CBK20722.2 - 0.1 12.7 1.5 7.9 6.5 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rhodanese PF00581.15 CBK20724.2 - 0.011 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain RNA_pol_L_2 PF13656.1 CBK20725.2 - 2.6e-26 90.8 0.0 3.3e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBK20725.2 - 1.9e-09 36.4 0.0 2.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Topoisom_bac PF01131.15 CBK20726.2 - 6.4e-81 272.2 0.0 8e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBK20726.2 - 4.3e-18 65.1 0.0 7.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain ACPS PF01648.15 CBK20727.2 - 7.9e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_transf_49 PF13896.1 CBK20728.2 - 1.8e-19 69.9 0.8 2.5e-15 56.4 0.2 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK20728.2 - 0.00026 20.1 0.2 0.00071 18.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Sed5p PF11416.3 CBK20728.2 - 0.066 12.6 0.6 0.18 11.2 0.4 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p Nol1_Nop2_Fmu PF01189.12 CBK20729.2 - 1.2e-31 110.1 0.0 3.4e-19 69.2 0.0 3.0 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBK20729.2 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1510 PF07423.6 CBK20729.2 - 0.015 14.6 14.7 0.03 13.6 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CBK20729.2 - 0.44 8.2 6.3 0.63 7.6 4.4 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CBK20729.2 - 0.71 8.8 4.1 1.1 8.2 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 CBK20729.2 - 1.3 8.9 6.7 2.1 8.2 4.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Myb_DNA-binding PF00249.26 CBK20730.2 - 1.1e-10 41.3 12.4 2.1e-10 40.4 0.5 3.8 3 1 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK20730.2 - 3.8e-07 30.1 9.7 4.7e-06 26.6 0.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain TRM13 PF05206.9 CBK20731.2 - 6.4e-54 182.9 2.7 9.3e-53 179.1 1.9 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 RNase_HII PF01351.13 CBK20731.2 - 1.6e-17 63.7 0.0 3.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease HII zf-U11-48K PF05253.7 CBK20731.2 - 8.5e-09 34.9 1.0 8.5e-09 34.9 0.7 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 CBK20731.2 - 8.7e-07 28.7 0.1 2.1e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain zf-TRM13_CCCH PF11722.3 CBK20731.2 - 4.3e-06 25.9 2.4 4.3e-06 25.9 1.6 3.0 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-C3Hc3H PF13891.1 CBK20731.2 - 0.006 16.6 0.7 0.006 16.6 0.5 2.7 2 0 0 2 2 2 1 Potential DNA-binding domain Methyltransf_12 PF08242.7 CBK20731.2 - 0.04 14.4 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RNase_HII PF01351.13 CBK20732.2 - 6.8e-23 81.3 0.0 8.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Rad51 PF08423.6 CBK20733.2 - 0.01 14.7 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Rad51 AAA_25 PF13481.1 CBK20733.2 - 0.021 14.2 0.0 0.039 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain CwfJ_C_1 PF04677.10 CBK20734.2 - 1.3e-27 95.9 0.1 2.8e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CBK20734.2 - 2.9e-07 30.8 0.7 2.9e-07 30.8 0.5 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 CBK20736.2 - 1.3e-68 230.9 0.0 1.6e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20736.2 - 4.9e-31 107.7 0.0 5.6e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK20736.2 - 0.00078 18.5 0.1 0.0014 17.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK20736.2 - 0.0017 18.0 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Spc97_Spc98 PF04130.8 CBK20737.2 - 5.9e-58 196.5 19.0 7.1e-58 196.2 13.2 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 CBK20738.2 - 6.2e-54 182.8 0.0 1.7e-53 181.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20738.2 - 6.6e-30 104.0 0.0 1.3e-25 90.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase LSM PF01423.17 CBK20738.2 - 1.2e-14 53.5 0.1 3.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 LSM domain APH PF01636.18 CBK20738.2 - 1e-05 25.4 0.0 0.0009 19.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBK20738.2 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CBK20738.2 - 0.027 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBK20738.2 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SecY PF00344.15 CBK20739.2 - 1.2e-84 284.2 11.9 1.7e-84 283.6 8.2 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBK20739.2 - 1.2e-18 66.2 0.2 4.2e-18 64.5 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p MNHE PF01899.11 CBK20739.2 - 0.13 11.9 2.1 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF1430 PF07242.6 CBK20739.2 - 1.8 8.6 6.3 11 6.1 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Ribosomal_S8 PF00410.14 CBK20740.2 - 8.6e-25 87.0 0.0 1.2e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Pribosyltran PF00156.22 CBK20741.2 - 1.5e-17 63.4 0.0 1.9e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBK20741.2 - 0.11 11.6 0.1 0.24 10.5 0.0 1.6 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase BPL_LplA_LipB PF03099.14 CBK20742.2 - 8.7e-11 41.9 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ECR1_N PF14382.1 CBK20743.2 - 1.4e-07 30.7 0.1 3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CBK20743.2 - 0.00057 19.7 0.1 0.059 13.3 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 CpcD PF01383.16 CBK20743.2 - 0.07 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Archease PF01951.11 CBK20744.2 - 3.3e-33 114.5 0.2 4.2e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ribosomal_L39 PF00832.15 CBK20745.2 - 1.1e-21 75.9 10.5 1.2e-21 75.8 7.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein PTPlike_phytase PF14566.1 CBK20746.2 - 5.5e-26 91.4 1.9 7.6e-26 90.9 0.1 1.9 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBK20746.2 - 0.07 13.3 2.1 0.34 11.1 0.4 2.5 2 1 0 2 2 2 0 Tyrosine phosphatase family PEGA PF08308.6 CBK20747.2 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PEGA domain RRM_6 PF14259.1 CBK20749.2 - 3.1e-05 23.8 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK20749.2 - 6e-05 22.5 0.0 0.00022 20.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20749.2 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rab5ip PF07019.7 CBK20750.2 - 5.8e-15 55.2 6.2 7.3e-15 54.8 4.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF1979 PF09322.5 CBK20751.2 - 0.011 15.3 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) RNA_POL_M_15KD PF02150.11 CBK20752.2 - 0.13 11.9 2.0 0.75 9.5 0.4 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Med27 PF11571.3 CBK20752.2 - 2.2 8.4 5.9 4.4 7.5 4.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 27 CFC PF09443.5 CBK20752.2 - 3.2 7.4 6.6 7.8 6.2 1.5 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) AMP-binding PF00501.23 CBK20753.2 - 4.5e-43 147.2 0.0 7.2e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.26 CBK20754.2 - 3.7e-27 93.8 0.1 8.7e-27 92.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CBK20754.2 - 1.6e-05 24.9 0.2 2.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBK20754.2 - 0.00026 21.0 0.2 0.00057 19.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBK20754.2 - 0.0093 15.8 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF4407 PF14362.1 CBK20754.2 - 0.042 12.8 4.3 0.056 12.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.21 CBK20754.2 - 0.12 12.7 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2317 PF10079.4 CBK20754.2 - 0.57 8.7 9.8 0.94 8.0 6.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4192 PF13830.1 CBK20754.2 - 4.6 6.7 7.4 7.6 6.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) PsiA PF06952.6 CBK20754.2 - 6 5.8 12.8 4.9 6.1 7.9 1.5 1 1 0 1 1 1 0 PsiA protein Ribosomal_S13 PF00416.17 CBK20755.2 - 6.4e-23 81.2 0.2 7.4e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Vps16_C PF04840.7 CBK20756.2 - 1.6e-16 60.1 4.9 4.5e-16 58.6 3.4 1.7 1 1 0 1 1 1 1 Vps16, C-terminal region Phage_lambd_GpG PF06894.6 CBK20756.2 - 0.051 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) Mito_carr PF00153.22 CBK20757.2 - 3.5e-56 186.9 2.4 7.7e-20 70.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PA PF02225.17 CBK20757.2 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 PA domain NMD3 PF04981.8 CBK20758.2 - 3.3e-53 180.2 0.4 4.4e-53 179.8 0.3 1.1 1 0 0 1 1 1 1 NMD3 family Macoilin PF09726.4 CBK20760.2 - 0.21 9.8 24.4 0.25 9.5 16.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 CBK20760.2 - 0.24 10.5 12.0 0.32 10.1 8.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NARP1 PF12569.3 CBK20760.2 - 0.32 9.7 4.7 0.42 9.3 3.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2457 PF10446.4 CBK20760.2 - 0.57 8.8 23.7 0.8 8.3 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CBK20760.2 - 0.58 9.3 13.4 0.82 8.8 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ycf1 PF05758.7 CBK20760.2 - 0.82 7.3 7.3 0.9 7.1 5.1 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CBK20760.2 - 2.1 8.1 7.1 3.1 7.6 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 CBK20760.2 - 5.1 6.8 22.5 7.8 6.2 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RAP1 PF07218.6 CBK20760.2 - 7.1 4.5 27.5 9.1 4.2 19.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF572 PF04502.8 CBK20760.2 - 8.8 5.4 24.9 13 4.9 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Actin PF00022.14 CBK20761.2 - 5.2e-92 308.2 0.0 6.1e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 Actin Kinesin PF00225.18 CBK20762.2 - 1.4e-103 346.1 0.8 2e-103 345.6 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CBK20762.2 - 0.0082 16.2 0.2 0.065 13.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Med4 PF10018.4 CBK20762.2 - 0.85 8.9 6.7 0.32 10.3 1.3 2.2 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1154 PF06631.6 CBK20762.2 - 1.3 8.7 3.6 8 6.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) DUF4201 PF13870.1 CBK20762.2 - 5.9 6.3 10.0 53 3.1 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) IncA PF04156.9 CBK20762.2 - 6.2 6.3 9.3 5.8 6.4 4.9 1.9 1 1 1 2 2 2 0 IncA protein Peptidase_C1 PF00112.18 CBK20763.2 - 1.4e-72 244.1 5.4 2.1e-72 243.5 3.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK20763.2 - 2.9e-10 40.2 1.8 5.5e-10 39.3 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBK20763.2 - 0.00058 18.4 3.4 0.21 10.0 0.7 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF167 PF02594.11 CBK20764.2 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 YokU PF14122.1 CBK20764.2 - 0.066 12.9 0.1 37 4.1 0.0 3.1 3 0 0 3 3 3 0 YokU-like protein SLA_LP_auto_ag PF05889.8 CBK20765.2 - 1.6e-123 412.0 0.0 1.9e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBK20765.2 - 0.018 14.2 0.0 0.043 12.9 0.0 1.5 1 1 1 2 2 2 0 Beta-eliminating lyase DUF2002 PF09400.5 CBK20765.2 - 0.034 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) WD40 PF00400.27 CBK20766.2 - 1.7e-61 202.0 27.0 7e-12 44.7 0.0 11.9 12 0 0 12 12 12 10 WD domain, G-beta repeat Nup160 PF11715.3 CBK20766.2 - 2.2e-07 29.3 2.0 0.037 12.1 0.0 5.2 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Utp12 PF04003.7 CBK20766.2 - 2.3e-06 27.4 0.2 5.5e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 CBK20766.2 - 4.1e-05 22.5 0.6 0.29 9.8 0.0 3.6 2 2 1 3 3 3 2 Nup133 N terminal like Apc4_WD40 PF12894.2 CBK20766.2 - 0.095 12.2 0.2 3.3 7.2 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M3 PF01432.15 CBK20768.2 - 1.5e-37 129.7 0.0 2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 MADF_DNA_bdg PF10545.4 CBK20768.2 - 0.03 14.5 0.5 1 9.6 0.2 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MORN PF02493.15 CBK20769.2 - 9.6e-09 34.4 7.2 0.00033 20.1 0.2 3.5 4 0 0 4 4 4 2 MORN repeat LRR_8 PF13855.1 CBK20769.2 - 0.0026 17.4 7.9 0.45 10.2 1.6 4.3 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 CBK20769.2 - 0.82 9.3 12.3 23 4.7 0.1 4.3 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) DDRGK PF09756.4 CBK20770.2 - 4 6.7 2.9 7.7 5.8 2.0 1.3 1 0 0 1 1 1 0 DDRGK domain Metal_resist PF13801.1 CBK20770.2 - 4.7 7.2 0.4 8.4 6.4 0.3 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Ras PF00071.17 CBK20771.2 - 7.3e-61 204.2 0.0 8.4e-61 204.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK20771.2 - 2.2e-21 76.5 0.0 4.4e-21 75.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK20771.2 - 6.1e-15 54.8 0.0 6.9e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK20771.2 - 2.9e-05 23.3 0.0 3.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK20771.2 - 0.0042 17.0 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase UQ_con PF00179.21 CBK20772.2 - 1.2e-36 125.1 0.1 1.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK20772.2 - 4.6e-05 23.1 0.0 5.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK20772.2 - 0.016 15.0 0.3 0.026 14.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain TauE PF01925.14 CBK20773.2 - 0.042 13.3 6.2 0.067 12.6 4.3 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Cytochrom_B_N PF00033.14 CBK20773.2 - 0.17 11.2 5.2 0.16 11.3 2.8 1.5 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1211 PF06736.6 CBK20773.2 - 0.32 11.1 4.4 0.97 9.6 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) DUF1705 PF08019.7 CBK20773.2 - 0.47 9.9 5.1 0.29 10.6 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1705) DUF2976 PF11190.3 CBK20773.2 - 0.65 9.5 5.6 0.12 11.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) DUF1119 PF06550.6 CBK20773.2 - 0.92 8.5 6.0 1.1 8.3 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) OppC_N PF12911.2 CBK20773.2 - 0.95 8.8 4.6 1.2 8.5 0.1 2.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C O-antigen_lig PF13425.1 CBK20773.2 - 2.1 8.2 15.4 3.5 7.6 3.7 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein P12 PF12669.2 CBK20773.2 - 3.8 7.7 9.8 16 5.7 0.8 3.2 3 0 0 3 3 3 0 Virus attachment protein p12 family DUF1129 PF06570.6 CBK20773.2 - 6.3 6.0 5.8 3.1 7.0 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) LMBR1 PF04791.11 CBK20774.2 - 7.5e-13 47.8 0.4 9.6e-13 47.5 0.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF334 PF03904.8 CBK20774.2 - 0.01 15.1 0.5 0.01 15.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF2207 PF09972.4 CBK20774.2 - 0.014 13.9 5.4 0.024 13.2 3.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.1 CBK20774.2 - 1.6 8.7 3.5 1.5 8.7 1.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) ThiF PF00899.16 CBK20776.2 - 1.5e-37 128.4 0.1 3.7e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 CBK20776.2 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ribosomal_S26e PF01283.14 CBK20776.2 - 0.014 15.5 0.6 0.045 13.9 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S26e ApbA PF02558.11 CBK20776.2 - 0.017 14.5 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 CBK20776.2 - 0.024 13.7 0.0 0.059 12.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBK20776.2 - 0.026 14.7 0.2 0.25 11.6 0.2 2.5 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CBK20776.2 - 0.029 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 CBK20776.2 - 0.09 11.8 1.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Peptidase_S9 PF00326.16 CBK20777.2 - 2e-22 79.4 0.0 3.2e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBK20777.2 - 2.6e-08 34.0 0.0 4.4e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBK20777.2 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBK20777.2 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CBK20777.2 - 0.075 12.4 0.0 0.44 9.9 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 CBK20777.2 - 0.078 12.3 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Het-C PF07217.6 CBK20777.2 - 0.2 9.7 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C PA28_beta PF02252.13 CBK20778.2 - 1.9e-19 69.6 0.0 2e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PRP38 PF03371.10 CBK20779.2 - 8.8e-31 106.8 0.0 1.5e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 PRP38 family DIX PF00778.12 CBK20779.2 - 0.0027 17.3 0.4 3.6 7.3 0.0 2.8 2 0 0 2 2 2 2 DIX domain Zip PF02535.17 CBK20779.2 - 2.7 6.9 18.9 0.019 13.9 7.5 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Innate_immun PF12782.2 CBK20779.2 - 3.1 6.9 17.7 4.7 6.3 12.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF1900 PF08954.6 CBK20780.2 - 1.1e-45 154.4 0.0 1.7e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CBK20780.2 - 1.6e-13 50.0 0.0 4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CBK20780.2 - 1.9e-13 49.7 0.2 0.00014 21.5 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat CCDC-167 PF15188.1 CBK20780.2 - 0.0072 16.2 2.6 0.012 15.5 1.8 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 VHP PF02209.14 CBK20781.2 - 7.7e-11 41.4 3.3 1.3e-10 40.7 2.3 1.4 1 0 0 1 1 1 1 Villin headpiece domain HTH_37 PF13744.1 CBK20781.2 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Frankia_peptide PF14407.1 CBK20781.2 - 0.035 13.8 0.4 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. LIM PF00412.17 CBK20782.2 - 3.8e-10 39.6 12.6 4e-09 36.3 4.6 2.3 2 0 0 2 2 2 2 LIM domain zf-MYND PF01753.13 CBK20782.2 - 0.016 15.0 6.9 0.22 11.4 1.5 2.5 1 1 1 2 2 2 0 MYND finger DUF1272 PF06906.6 CBK20782.2 - 0.016 15.0 8.9 0.057 13.2 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-FCS PF06467.9 CBK20782.2 - 0.052 13.1 0.2 0.052 13.1 0.1 4.3 3 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-B_box PF00643.19 CBK20782.2 - 0.056 13.3 1.1 0.056 13.3 0.8 3.0 2 1 0 2 2 2 0 B-box zinc finger Ecl1 PF12855.2 CBK20782.2 - 3.4 7.0 8.2 4.2 6.7 0.0 2.7 1 1 1 2 2 2 0 Life-span regulatory factor DUF4428 PF14471.1 CBK20782.2 - 3.6 7.4 11.7 6 6.6 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Arif-1 PF06770.6 CBK20782.2 - 5.4 6.3 11.0 0.99 8.7 4.4 2.0 1 1 1 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) VHP PF02209.14 CBK20783.2 - 1.5e-14 53.3 0.8 1.5e-14 53.3 0.5 2.4 2 0 0 2 2 2 1 Villin headpiece domain PAP2 PF01569.16 CBK20784.2 - 2.2e-09 37.0 0.4 2.2e-09 37.0 0.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF106 PF01956.11 CBK20784.2 - 0.03 13.8 7.3 0.081 12.4 1.0 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF106 DUF212 PF02681.9 CBK20784.2 - 0.048 13.3 0.1 0.094 12.4 0.0 1.5 1 1 1 2 2 2 0 Divergent PAP2 family VP7 PF00434.13 CBK20784.2 - 0.083 11.7 1.0 0.1 11.4 0.7 1.1 1 0 0 1 1 1 0 Glycoprotein VP7 ArfGap PF01412.13 CBK20785.2 - 1.4e-42 144.1 2.4 1.4e-42 144.1 1.7 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PAT1 PF09770.4 CBK20785.2 - 0.0071 14.6 59.2 0.012 13.9 41.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Nucleoplasmin PF03066.10 CBK20785.2 - 0.011 15.2 3.0 0.021 14.3 2.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin Med15 PF09606.5 CBK20785.2 - 0.013 13.7 73.7 0.017 13.3 51.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HC2 PF07382.6 CBK20785.2 - 0.013 15.3 7.5 0.013 15.3 5.2 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 DUF810 PF05664.6 CBK20785.2 - 0.054 11.7 0.2 0.076 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF810) KRTAP PF11759.3 CBK20785.2 - 0.44 10.8 11.3 24 5.2 7.8 2.3 1 1 0 1 1 1 0 Keratin-associated matrix DUF4611 PF15387.1 CBK20785.2 - 3 8.0 8.4 0.68 10.1 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Aa_trans PF01490.13 CBK20787.2 - 1.6e-55 188.2 31.5 2e-55 187.9 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBK20787.2 - 1.8e-07 30.3 29.7 3.7e-07 29.3 20.6 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Histone PF00125.19 CBK20788.2 - 9.7e-15 54.4 0.1 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBK20788.2 - 6e-05 22.9 0.1 8.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CBK20788.2 - 8.1e-05 22.7 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20788.2 - 0.00075 19.5 0.1 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBK20788.2 - 0.016 14.9 0.1 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HTH_17 PF12728.2 CBK20788.2 - 0.048 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-31kDa PF02291.10 CBK20788.2 - 0.07 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 CBK20788.2 - 0.15 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 CBK20789.2 - 7.6e-33 112.4 0.5 1.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK20789.2 - 5.8e-05 23.1 0.1 8.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK20789.2 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_6 PF13405.1 CBK20790.2 - 0.00035 20.2 0.3 0.0011 18.7 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CBK20790.2 - 0.00056 19.0 0.1 0.0013 17.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBK20790.2 - 0.001 19.1 0.7 0.005 16.9 0.6 2.1 1 1 0 1 1 1 1 EF-hand domain pair DUF621 PF04789.10 CBK20790.2 - 0.023 13.7 1.2 0.034 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) DUF3867 PF12983.2 CBK20790.2 - 0.024 14.6 0.6 0.046 13.6 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF4422 PF14393.1 CBK20790.2 - 0.06 12.9 0.8 0.14 11.7 0.2 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4422) Pkinase PF00069.20 CBK20791.2 - 3.9e-68 229.4 0.0 4.8e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20791.2 - 6.3e-33 113.9 0.0 1.4e-32 112.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20791.2 - 1.7e-05 23.9 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK20791.2 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSP70 PF00012.15 CBK20792.2 - 2e-19 68.9 0.0 3.8e-19 68.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein Actin PF00022.14 CBK20792.2 - 0.00051 18.5 0.0 0.00079 17.9 0.0 1.3 1 0 0 1 1 1 1 Actin OB_NTP_bind PF07717.11 CBK20793.2 - 1.8e-25 88.9 0.0 4.4e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBK20793.2 - 3.9e-23 81.4 0.0 8.9e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBK20793.2 - 2.1e-10 40.3 0.0 4.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK20793.2 - 1.9e-06 27.4 0.1 4.2e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK20793.2 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 CBK20793.2 - 0.00051 19.8 0.1 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain Podovirus_Gp16 PF05894.7 CBK20793.2 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Podovirus DNA encapsidation protein (Gp16) ResIII PF04851.10 CBK20793.2 - 0.012 15.4 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CBK20793.2 - 0.045 14.0 4.4 0.47 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK20793.2 - 0.047 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Clat_adaptor_s PF01217.15 CBK20794.2 - 9.4e-45 151.8 7.7 1e-44 151.6 5.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GDE_C PF06202.9 CBK20794.2 - 0.019 13.6 0.2 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase EF-hand_5 PF13202.1 CBK20795.2 - 0.0007 18.8 0.4 0.0016 17.7 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBK20795.2 - 0.00088 19.3 0.1 0.0019 18.3 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBK20795.2 - 0.0017 18.0 0.1 0.0056 16.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CBK20795.2 - 0.0017 17.4 0.4 0.0049 16.0 0.3 1.8 1 0 0 1 1 1 1 EF hand Sex_peptide PF08138.6 CBK20796.2 - 0.054 13.3 0.7 1.4 8.7 0.6 2.4 2 0 0 2 2 2 0 Sex peptide (SP) family EGF_2 PF07974.8 CBK20796.2 - 0.066 13.3 9.6 0.29 11.3 6.6 2.2 1 1 0 1 1 1 0 EGF-like domain AP2 PF00847.15 CBK20797.2 - 0.00089 19.3 0.8 0.0018 18.4 0.5 1.5 1 0 0 1 1 1 1 AP2 domain TFIID_20kDa PF03847.8 CBK20798.2 - 5.6e-09 36.1 0.0 7.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID_30kDa PF03540.8 CBK20798.2 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Dus PF01207.12 CBK20799.2 - 7.2e-45 153.1 0.0 9.5e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CBK20799.2 - 2.7e-07 30.0 6.4 0.00056 19.5 0.1 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cyclin PF08613.6 CBK20800.2 - 2.1e-23 83.4 3.7 3.2e-23 82.8 2.5 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBK20800.2 - 5e-09 35.8 0.3 7e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HMG_box_2 PF09011.5 CBK20802.2 - 4.5e-13 49.3 0.8 9.5e-13 48.3 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBK20802.2 - 4.6e-12 46.0 0.3 9.7e-12 44.9 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box zf-C2H2 PF00096.21 CBK20802.2 - 0.00084 19.5 7.3 0.018 15.3 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type MCR_beta PF02241.13 CBK20802.2 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain zf-C2H2_4 PF13894.1 CBK20802.2 - 2.3 8.7 7.1 0.78 10.2 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK20803.2 - 1.6e-13 50.2 8.0 6.3e-07 29.3 0.0 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBK20803.2 - 8.7e-11 41.5 4.6 2e-06 27.7 0.3 2.7 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK20803.2 - 3.4e-08 33.2 2.6 0.00029 20.9 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBK20803.2 - 0.00011 22.1 7.7 0.025 14.6 0.2 3.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding DUF1644 PF07800.7 CBK20803.2 - 0.0078 16.0 2.8 0.013 15.4 1.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1644) zf-C2HC_2 PF13913.1 CBK20803.2 - 0.012 15.2 0.3 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CHORD PF04968.7 CBK20803.2 - 0.017 15.3 3.0 1.5 9.1 0.2 2.2 1 1 1 2 2 2 0 CHORD zf-C2H2_6 PF13912.1 CBK20803.2 - 0.04 13.8 1.1 0.04 13.8 0.7 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CBK20803.2 - 0.14 12.2 4.9 7.1 6.8 0.2 2.8 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 CBK20803.2 - 0.15 11.7 2.0 0.64 9.7 0.0 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-met PF12874.2 CBK20803.2 - 0.26 11.5 9.1 1.3 9.2 0.0 3.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 CBK20803.2 - 0.58 10.5 5.5 0.93 9.9 3.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger Glutaredoxin PF00462.19 CBK20804.2 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin EF1G PF00647.14 CBK20805.2 - 2.5e-34 117.1 0.1 4.6e-34 116.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain DUF3583 PF12126.3 CBK20805.2 - 0.082 11.9 0.5 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Pox_P35 PF03213.9 CBK20805.2 - 0.22 10.4 1.6 2.7 6.9 0.4 2.0 2 0 0 2 2 2 0 Poxvirus P35 protein OAD_gamma PF04277.8 CBK20805.2 - 3.8 7.9 5.0 7.6 6.9 3.4 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Mo25 PF08569.6 CBK20806.2 - 4.2e-73 246.2 9.8 4.7e-73 246.1 6.8 1.0 1 0 0 1 1 1 1 Mo25-like TFIIA_gamma_N PF02268.11 CBK20806.2 - 0.037 13.6 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Ribosomal_L18p PF00861.17 CBK20807.2 - 2.6e-42 143.7 0.5 2.6e-42 143.7 0.3 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBK20807.2 - 1.3e-31 109.0 5.9 2.3e-31 108.2 4.1 1.4 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region TPR_11 PF13414.1 CBK20808.2 - 9.3e-08 31.6 6.3 0.00023 20.7 0.4 2.6 1 1 0 2 2 2 2 TPR repeat TPR_9 PF13371.1 CBK20808.2 - 0.0011 18.7 1.6 0.0076 16.0 0.9 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK20808.2 - 0.0026 17.2 5.9 0.15 11.7 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20808.2 - 0.0031 17.3 7.3 0.024 14.5 0.9 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat PMEI PF04043.10 CBK20808.2 - 0.0039 17.0 1.6 0.023 14.5 1.1 2.1 1 1 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor TPR_12 PF13424.1 CBK20808.2 - 0.039 13.9 6.3 2.5 8.0 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20808.2 - 0.039 14.6 0.2 0.039 14.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.8 CBK20808.2 - 1.9 8.1 17.5 4 7.0 12.1 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CybS PF05328.7 CBK20809.2 - 5e-13 48.8 1.0 6e-13 48.5 0.7 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 CBK20809.2 - 0.035 13.9 0.2 0.053 13.3 0.2 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit AMP-binding PF00501.23 CBK20810.2 - 8.6e-78 261.5 0.0 1.6e-77 260.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.5 CBK20810.2 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Myb_DNA-binding PF00249.26 CBK20813.2 - 9e-42 140.9 12.7 4.2e-14 52.3 1.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK20813.2 - 2.6e-37 126.7 11.1 9.1e-15 54.5 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.5 CBK20813.2 - 1e-05 25.2 0.0 0.12 12.0 0.0 3.3 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.1 CBK20813.2 - 0.0053 16.8 11.1 0.5 10.5 0.7 4.0 4 1 0 4 4 4 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CBK20813.2 - 0.013 15.3 1.9 16 5.4 0.0 3.6 2 2 1 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.3 CBK20813.2 - 0.027 14.3 7.1 6.3 6.7 0.3 3.3 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 CBK20813.2 - 0.048 13.5 9.0 3.5 7.5 2.2 4.3 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain DUF288 PF03385.12 CBK20814.2 - 3.1e-12 45.6 0.1 5.4e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF288 zf-B_box PF00643.19 CBK20815.2 - 2.5e-05 24.0 10.8 2.5e-05 24.0 7.5 2.4 2 0 0 2 2 2 1 B-box zinc finger zf-RING_5 PF14634.1 CBK20815.2 - 0.013 15.2 13.9 0.21 11.3 7.3 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 CBK20815.2 - 0.029 13.8 5.9 0.059 12.8 4.1 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain REV PF00424.13 CBK20815.2 - 0.03 14.2 1.0 0.057 13.3 0.7 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Aha1_N PF09229.6 CBK20815.2 - 0.037 13.8 3.8 0.056 13.2 2.6 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal PHF5 PF03660.9 CBK20815.2 - 0.077 13.0 5.7 0.037 14.0 2.0 1.9 2 0 0 2 2 2 0 PHF5-like protein Lactamase_B_5 PF14597.1 CBK20815.2 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Transposase_24 PF03004.9 CBK20815.2 - 0.12 12.2 0.1 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) zf-UBP PF02148.14 CBK20815.2 - 0.28 11.3 8.6 0.79 9.8 6.0 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein ZZ PF00569.12 CBK20815.2 - 0.39 10.2 15.3 0.099 12.1 7.4 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-C3HC4 PF00097.20 CBK20815.2 - 0.56 9.9 18.2 0.14 11.8 9.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK20815.2 - 0.68 9.6 16.9 0.027 14.1 6.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMEM51 PF15345.1 CBK20815.2 - 0.75 9.4 6.3 1.6 8.3 4.4 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 zf-C3HC4_2 PF13923.1 CBK20815.2 - 0.76 9.8 18.7 0.09 12.8 7.3 2.9 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Tetraspannin PF00335.15 CBK20815.2 - 1.1 8.4 3.7 0.36 10.0 0.7 1.5 2 0 0 2 2 2 0 Tetraspanin family HD_3 PF13023.1 CBK20816.2 - 4.5e-42 143.5 0.0 5.5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 HD domain HD PF01966.17 CBK20816.2 - 0.0016 18.4 0.0 0.0085 16.1 0.0 2.0 1 1 0 1 1 1 1 HD domain RTC PF01137.16 CBK20817.2 - 2.2e-62 209.8 0.0 2.8e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CBK20817.2 - 5.7e-26 90.5 0.0 8.4e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.16 CBK20818.2 - 3e-46 157.4 0.0 9e-46 155.9 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CBK20818.2 - 1.9e-13 50.2 7.6 1.9e-13 50.2 5.3 1.8 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 CBK20818.2 - 0.0027 17.1 0.2 0.012 15.1 0.1 2.1 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Fez1 PF06818.10 CBK20818.2 - 0.0072 16.3 0.6 0.013 15.5 0.4 1.4 1 0 0 1 1 1 1 Fez1 U-box PF04564.10 CBK20818.2 - 0.016 15.1 0.0 0.065 13.2 0.0 2.1 1 1 1 2 2 2 0 U-box domain FHA PF00498.21 CBK20820.2 - 2.6e-19 69.1 0.0 5.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Peptidase_C13 PF01650.13 CBK20821.2 - 1.8e-10 40.5 3.3 2.5e-10 40.0 2.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family FixQ PF05545.6 CBK20822.2 - 0.0087 15.6 0.0 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ Uso1_p115_head PF04869.9 CBK20822.2 - 0.081 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region EGF_2 PF07974.8 CBK20822.2 - 0.16 12.1 7.7 0.39 10.9 5.3 1.7 1 0 0 1 1 1 0 EGF-like domain Pkinase PF00069.20 CBK20823.2 - 5.5e-36 124.0 0.0 6.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20823.2 - 4e-12 45.7 0.0 4.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK20823.2 - 0.011 14.7 0.0 0.21 10.5 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBK20823.2 - 0.033 12.9 0.3 0.051 12.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Scramblase PF03803.10 CBK20824.2 - 3e-52 176.9 0.0 4.3e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Scramblase Nuc_sug_transp PF04142.10 CBK20825.2 - 3e-70 236.1 17.3 3e-70 236.1 12.0 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CBK20825.2 - 7.5e-11 42.1 29.4 5.3e-08 32.9 3.0 2.8 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBK20825.2 - 4e-08 32.5 22.1 1.5e-07 30.6 15.3 2.2 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBK20825.2 - 3.7e-07 29.9 3.6 3.7e-07 29.9 2.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 CBK20825.2 - 0.00011 22.3 1.0 0.00011 22.3 0.7 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF1195 PF06708.6 CBK20825.2 - 0.21 10.9 0.7 0.43 10.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Chorein_N PF12624.2 CBK20826.2 - 3.5e-36 123.3 1.9 1.9e-35 120.9 1.3 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PX PF00787.19 CBK20827.2 - 0.0023 17.7 0.8 0.0049 16.6 0.6 1.5 1 0 0 1 1 1 1 PX domain ATG_C PF09333.6 CBK20827.2 - 0.037 14.1 0.1 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 ATG C terminal domain He_PIG PF05345.7 CBK20828.2 - 1.4e-25 89.0 51.1 9.1e-07 28.8 1.2 8.8 8 0 0 8 8 8 7 Putative Ig domain S-AdoMet_synt_C PF02773.11 CBK20829.2 - 8.9e-75 248.9 0.1 1.6e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBK20829.2 - 7.8e-50 167.8 0.1 1.8e-49 166.6 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBK20829.2 - 3.7e-42 142.5 0.2 3.7e-42 142.5 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain WW PF00397.21 CBK20830.2 - 0.00036 20.3 1.9 0.00054 19.7 1.3 1.3 1 0 0 1 1 1 1 WW domain Acyltransferase PF01553.16 CBK20831.2 - 9.4e-21 73.6 0.0 2.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase AhpC-TSA PF00578.16 CBK20832.2 - 6.3e-37 126.0 0.0 8.7e-37 125.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK20832.2 - 1.8e-14 53.5 0.0 2.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK20832.2 - 1e-11 44.2 0.0 2.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PGK PF00162.14 CBK20833.2 - 9.6e-149 495.1 2.7 1.1e-148 494.8 1.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DASH_Duo1 PF08651.5 CBK20834.2 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 Cullin PF00888.17 CBK20836.2 - 6.8e-14 51.3 2.9 2e-13 49.7 0.5 2.2 2 0 0 2 2 2 2 Cullin family Ribosomal_S13 PF00416.17 CBK20837.2 - 6.4e-23 81.2 0.2 7.4e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 SUR7 PF06687.7 CBK20838.2 - 0.069 12.7 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 SUR7/PalI family Tricorn_C1 PF14684.1 CBK20838.2 - 0.12 12.3 0.8 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain Lipase_3 PF01764.20 CBK20839.2 - 8.4e-13 48.1 0.0 2.4e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF433 PF04255.9 CBK20839.2 - 0.023 14.1 0.1 2 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Lactamase_B_3 PF13483.1 CBK20840.2 - 3.8e-18 65.7 0.0 4.8e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 CBK20840.2 - 1.9e-12 47.1 0.1 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK20840.2 - 0.00047 19.8 1.2 0.0044 16.6 0.8 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-H2C2_2 PF13465.1 CBK20842.2 - 1.6e-24 84.9 35.2 2.4e-07 30.7 0.2 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBK20842.2 - 1.3e-15 56.6 35.1 7.7e-05 22.8 0.4 5.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CBK20842.2 - 1.7e-14 53.0 25.9 0.01 16.0 0.1 5.7 5 0 0 5 5 5 5 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CBK20842.2 - 2.3e-11 43.1 32.3 0.0071 16.6 0.5 5.6 6 0 0 6 6 6 5 C2H2-type zinc finger DUF3505 PF12013.3 CBK20842.2 - 0.0096 16.1 18.2 6 7.1 0.1 5.3 3 2 2 5 5 5 3 Protein of unknown function (DUF3505) IBR PF01485.16 CBK20842.2 - 0.96 9.3 19.5 21 5.0 1.7 5.3 1 1 2 3 3 3 0 IBR domain DUF711 PF05167.7 CBK20843.2 - 6.8e-07 28.3 0.1 7e-07 28.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) DUF458 PF04308.7 CBK20843.2 - 0.1 12.3 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF458) DUF711 PF05167.7 CBK20844.2 - 1.9e-28 99.3 0.0 2.3e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) Ribosomal_L35Ae PF01247.13 CBK20846.2 - 6.7e-33 112.3 1.6 7.6e-33 112.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Cadherin-like PF12733.2 CBK20846.2 - 0.11 12.8 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Bromodomain PF00439.20 CBK20847.2 - 1.7e-18 66.2 0.5 3.6e-18 65.2 0.3 1.6 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 CBK20847.2 - 5.8e-10 39.2 1.7 6.2e-10 39.0 0.4 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK20847.2 - 7.7e-08 32.2 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBK20847.2 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK20847.2 - 0.0032 17.4 1.3 0.0051 16.7 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Y_phosphatase2 PF03162.8 CBK20848.2 - 3.6e-35 120.7 0.5 4e-35 120.6 0.4 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-C3HC4_3 PF13920.1 CBK20849.2 - 1.7e-06 27.6 12.5 1.7e-06 27.6 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK20849.2 - 4.6e-06 26.5 15.2 4.6e-06 26.5 10.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK20849.2 - 5.2e-06 26.0 14.8 1.3e-05 24.7 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20849.2 - 5.8e-05 22.7 12.9 5.8e-05 22.7 9.0 2.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBK20849.2 - 9e-05 22.2 12.9 9e-05 22.2 8.9 2.3 2 1 1 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 CBK20849.2 - 0.00015 21.7 6.8 0.00015 21.7 4.7 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 CBK20849.2 - 0.00022 20.9 3.7 0.00052 19.7 2.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CBK20849.2 - 0.00093 18.9 3.0 0.002 17.9 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBK20849.2 - 0.0015 18.2 10.5 0.0037 16.9 7.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger KSHV_K1 PF11049.3 CBK20849.2 - 0.018 14.9 0.3 0.03 14.3 0.2 1.3 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Prok-RING_4 PF14447.1 CBK20849.2 - 0.086 12.3 6.9 0.24 10.9 4.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 CBK20849.2 - 0.1 12.1 9.3 0.19 11.2 6.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CBK20849.2 - 0.61 9.7 14.2 29 4.3 10.3 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain AAA PF00004.24 CBK20850.2 - 5.4e-36 123.7 0.0 1.8e-35 122.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK20850.2 - 9.3e-06 25.7 0.2 5.2e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBK20850.2 - 0.00021 21.4 0.3 0.049 13.7 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 CBK20850.2 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBK20850.2 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK20850.2 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.9 CBK20850.2 - 0.003 17.5 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBK20850.2 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CBK20850.2 - 0.012 15.2 0.0 0.56 9.8 0.0 2.5 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 CBK20850.2 - 0.02 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 CBK20850.2 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBK20850.2 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CBK20850.2 - 0.036 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 CBK20850.2 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 CBK20850.2 - 0.071 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 CBK20850.2 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBK20850.2 - 0.073 11.7 0.0 0.15 10.6 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 CBK20850.2 - 0.089 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK20850.2 - 0.095 12.0 0.1 0.48 9.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBK20850.2 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Bax1-I PF01027.15 CBK20851.2 - 2e-26 92.9 21.5 2.3e-26 92.7 14.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Nucleos_tra2_N PF01773.15 CBK20851.2 - 0.28 11.5 3.8 0.44 10.9 0.6 2.4 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus NnrU PF07298.6 CBK20851.2 - 5.7 6.2 8.2 18 4.6 3.7 2.6 1 1 1 2 2 2 0 NnrU protein Bax1-I PF01027.15 CBK20852.2 - 1.1e-05 25.1 5.0 1.2e-05 24.9 3.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4173 PF13777.1 CBK20852.2 - 0.15 11.3 5.7 0.16 11.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) zf-RING_2 PF13639.1 CBK20853.2 - 1.1e-15 57.1 5.3 1.6e-15 56.6 3.3 1.6 2 0 0 2 2 1 1 Ring finger domain PA PF02225.17 CBK20853.2 - 1.1e-10 41.0 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 CBK20853.2 - 3.5e-09 36.5 6.0 6.8e-09 35.6 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20853.2 - 7.7e-09 35.1 3.7 1.2e-08 34.4 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBK20853.2 - 8.4e-09 35.4 1.3 1.7e-08 34.4 0.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBK20853.2 - 1.3e-08 34.3 4.7 2.2e-08 33.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK20853.2 - 9e-08 31.6 3.1 1.5e-07 30.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBK20853.2 - 7.8e-06 25.6 1.7 3.1e-05 23.7 1.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBK20853.2 - 0.00021 20.9 2.4 0.00085 18.9 0.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.1 CBK20853.2 - 0.002 17.8 3.6 0.067 12.9 0.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 CBK20853.2 - 0.0033 16.9 3.0 0.0059 16.1 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBK20853.2 - 0.0038 17.0 4.1 0.0083 15.9 2.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CBK20853.2 - 0.015 15.2 2.6 0.052 13.5 1.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CBK20853.2 - 0.039 13.6 3.1 0.082 12.6 2.1 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_6 PF14835.1 CBK20853.2 - 0.044 13.5 0.5 0.18 11.5 0.5 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RINGv PF12906.2 CBK20853.2 - 0.047 13.7 4.7 0.11 12.5 3.3 1.6 1 0 0 1 1 1 0 RING-variant domain Rtf2 PF04641.7 CBK20853.2 - 0.14 11.3 0.2 0.23 10.6 0.1 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 CBK20853.2 - 0.19 11.2 3.3 0.44 10.1 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Collagen PF01391.13 CBK20854.2 - 6.6e-29 99.2 110.0 2e-08 33.6 18.1 4.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DNA_pol_B_2 PF03175.8 CBK20855.2 - 4.2e-08 32.2 7.6 0.00076 18.2 0.3 3.4 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral zf-C3HC4_3 PF13920.1 CBK20856.2 - 2.9e-09 36.4 9.6 2.9e-09 36.4 6.7 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK20856.2 - 1.6e-08 34.2 19.1 7.7e-06 25.6 8.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 CBK20856.2 - 3e-07 29.9 12.0 3e-07 29.9 8.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK20856.2 - 1.4e-05 24.9 12.9 1.4e-05 24.9 9.0 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20856.2 - 4.7e-05 23.0 11.0 4.7e-05 23.0 7.6 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBK20856.2 - 0.0031 17.3 10.6 0.0031 17.3 7.3 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBK20856.2 - 0.0086 15.7 8.3 0.017 14.8 2.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Pox_MCEL PF03291.11 CBK20856.2 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme zf-Apc11 PF12861.2 CBK20856.2 - 0.66 9.8 7.8 2.2 8.2 5.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.7 CBK20856.2 - 2.2 8.4 13.8 0.44 10.7 0.8 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 CBK20856.2 - 8.2 6.1 18.0 1.6 8.3 6.4 2.9 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CBK20858.2 - 1.9e-07 30.6 7.9 3.2e-07 29.9 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK20858.2 - 2.8e-06 26.8 11.0 7e-06 25.5 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK20858.2 - 3.4e-05 23.7 8.2 3.4e-05 23.7 5.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK20858.2 - 0.00022 20.9 11.1 0.00034 20.2 6.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBK20858.2 - 0.00023 20.9 13.1 0.00038 20.2 8.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBK20858.2 - 0.66 10.1 8.6 2 8.5 5.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CBK20858.2 - 1.2 8.8 18.9 0.047 13.2 8.2 2.4 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBK20858.2 - 1.7 8.4 7.2 4.3 7.1 1.3 2.6 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 CBK20858.2 - 2.7 7.8 6.3 2.8 7.7 3.3 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBK20858.2 - 8.5 6.3 16.2 12 5.8 8.6 3.2 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Peptidase_C13 PF01650.13 CBK20860.2 - 1.8e-58 197.8 0.1 2.5e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF3242 PF11586.3 CBK20860.2 - 0.0037 16.7 1.9 0.0083 15.6 0.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3242) PHD PF00628.24 CBK20861.2 - 5.3e-06 26.0 8.1 5.3e-06 26.0 5.6 4.2 4 1 1 5 5 5 1 PHD-finger zf-C2H2 PF00096.21 CBK20861.2 - 0.011 15.9 4.5 0.011 15.9 3.1 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 CBK20861.2 - 0.052 13.7 6.2 0.38 11.0 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.6 CBK20861.2 - 3.8 7.1 8.3 0.16 11.5 1.2 2.1 2 0 0 2 2 2 0 GAGA factor Mrr_cat PF04471.7 CBK20862.2 - 1.9e-09 37.3 0.3 7.1e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease PHA_synth_III_E PF09712.5 CBK20862.2 - 0.0061 15.9 1.6 0.011 15.1 1.1 1.3 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Toxin_61 PF15538.1 CBK20862.2 - 0.015 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 61 DUF3287 PF11690.3 CBK20862.2 - 0.044 13.8 0.1 0.044 13.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) CRISPR_Cse1 PF09481.5 CBK20862.2 - 0.13 10.9 2.0 2 7.1 0.3 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF1279 PF06916.8 CBK20862.2 - 0.13 12.5 0.3 0.79 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) YpjP PF14005.1 CBK20862.2 - 0.42 10.3 5.3 0.15 11.8 1.8 1.6 2 0 0 2 2 2 0 YpjP-like protein adh_short PF00106.20 CBK20863.2 - 4.8e-30 104.6 0.0 6.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBK20863.2 - 2.4e-14 53.7 0.0 3.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBK20863.2 - 2.8e-12 46.6 0.0 3.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 CBK20863.2 - 0.0044 16.1 0.1 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 CBK20863.2 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L13 PF00572.13 CBK20864.2 - 9.2e-27 93.6 0.0 1.5e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 FAD_binding_2 PF00890.19 CBK20865.2 - 2e-121 405.7 3.2 2.7e-121 405.3 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBK20865.2 - 7.7e-48 161.5 1.8 1.1e-47 161.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBK20865.2 - 1.2e-06 27.7 0.1 8.6e-06 24.8 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBK20865.2 - 1.4e-06 27.6 0.2 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CBK20865.2 - 2.6e-05 24.2 1.4 0.00034 20.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBK20865.2 - 4.5e-05 22.4 0.9 0.0025 16.7 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CBK20865.2 - 0.00027 20.1 0.2 0.00045 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CBK20865.2 - 0.017 15.4 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 CBK20865.2 - 0.022 13.2 1.5 0.038 12.4 0.2 2.0 3 0 0 3 3 3 0 HI0933-like protein NodZ PF05830.6 CBK20866.2 - 2.6e-05 22.9 0.0 8e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) XG_FTase PF03254.8 CBK20866.2 - 6.1e-05 21.7 0.1 0.01 14.3 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase MORN PF02493.15 CBK20867.2 - 2.7e-12 45.6 43.5 0.035 13.8 0.2 11.3 12 0 0 12 12 12 5 MORN repeat LRR_8 PF13855.1 CBK20867.2 - 3.6e-05 23.4 0.2 0.47 10.2 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBK20867.2 - 8.4e-05 22.0 0.1 0.55 9.9 0.0 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.1 CBK20867.2 - 0.062 13.0 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) RCC1 PF00415.13 CBK20868.2 - 1.3e-33 114.9 2.9 2.4e-09 37.2 0.0 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK20868.2 - 1.8e-30 103.8 23.6 2.6e-07 30.0 1.6 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 CBK20869.2 - 5e-69 232.8 0.0 5.9e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Suf PF05843.9 CBK20870.2 - 0.00036 20.3 4.4 0.3 10.7 0.0 3.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CBK20870.2 - 0.0019 18.8 2.5 4.8 7.9 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20870.2 - 0.0053 17.2 12.6 5.7 7.8 0.4 6.9 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20870.2 - 0.055 13.3 3.2 2.2 8.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MCPVI PF02993.9 CBK20870.2 - 0.33 11.0 4.4 0.57 10.2 3.1 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Mob1_phocein PF03637.12 CBK20871.2 - 4.4e-48 163.2 0.8 6.7e-48 162.6 0.6 1.2 1 0 0 1 1 1 1 Mob1/phocein family Trypan_PARP PF05887.6 CBK20873.2 - 1.3 8.8 49.9 0.68 9.7 4.7 2.8 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Methyltransf_28 PF02636.12 CBK20875.2 - 9.6e-26 90.6 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lyase_1 PF00206.15 CBK20876.2 - 4e-93 312.0 0.0 7.8e-93 311.0 0.0 1.4 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.4 CBK20876.2 - 1.4e-20 73.1 0.0 4.6e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus Thioredoxin PF00085.15 CBK20878.2 - 9.2e-06 25.2 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBK20878.2 - 0.025 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain GTP_EFTU PF00009.22 CBK20879.2 - 3.7e-60 202.5 0.0 5e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK20879.2 - 5.2e-29 100.3 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK20879.2 - 1.5e-16 60.2 3.0 4e-16 58.8 2.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK20879.2 - 8.8e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBK20879.2 - 7.3e-05 22.3 1.4 0.00023 20.7 1.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CBK20879.2 - 0.0067 16.9 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 CBK20879.2 - 0.045 13.2 0.3 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored_q6 PF01058.17 CBK20880.2 - 4.9e-23 81.1 0.0 7.5e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_LYR_2 PF13233.1 CBK20881.2 - 0.0032 17.9 0.2 0.0049 17.3 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBK20881.2 - 0.1 12.3 0.2 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) SNF2_N PF00176.18 CBK20882.2 - 4.3e-40 137.3 0.0 5.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK20882.2 - 3.1e-10 39.7 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBK20882.2 - 4.8e-07 28.8 0.1 0.0015 17.3 0.2 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBK20882.2 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK20882.2 - 0.00081 19.2 0.0 0.0022 17.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LRR_6 PF13516.1 CBK20883.2 - 2.9e-15 54.5 0.3 0.31 11.2 0.0 9.4 9 0 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.1 CBK20883.2 - 3.4e-07 29.9 4.4 1.9 8.3 0.3 6.0 4 3 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CBK20883.2 - 1e-06 28.2 3.2 0.66 9.6 0.0 6.1 3 3 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBK20883.2 - 1.3e-05 24.5 3.6 7.7 6.9 0.1 6.6 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBK20883.2 - 9e-05 22.0 7.7 8.7 7.0 0.0 7.2 7 0 0 7 7 7 1 Leucine rich repeat FBD PF08387.5 CBK20883.2 - 0.16 11.4 1.4 5.8 6.4 0.1 2.9 2 1 0 2 2 2 0 FBD Aha1_N PF09229.6 CBK20884.2 - 1.9e-18 66.6 0.2 3.5e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal ComZ PF10815.3 CBK20884.2 - 0.028 14.1 0.3 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 ComZ Ribosomal_L14 PF00238.14 CBK20885.2 - 1.2e-33 115.4 0.0 1.3e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ICMT PF04140.9 CBK20886.2 - 2.6e-22 78.8 0.1 2.6e-22 78.8 0.0 1.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBK20886.2 - 2.5e-10 40.3 1.6 2.5e-10 40.3 1.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CBK20886.2 - 0.0029 16.9 0.5 0.0029 16.9 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PrgI PF12666.2 CBK20886.2 - 0.017 15.2 4.3 0.022 14.8 0.6 2.3 2 0 0 2 2 2 0 PrgI family protein FtsX PF02687.16 CBK20886.2 - 0.17 11.6 5.8 1.4 8.6 1.3 2.3 2 0 0 2 2 2 0 FtsX-like permease family PRTP PF01366.13 CBK20887.2 - 0.018 13.0 0.9 0.027 12.4 0.4 1.4 1 1 0 1 1 1 0 Herpesvirus processing and transport protein SdpI PF13630.1 CBK20888.2 - 0.025 14.3 14.0 0.44 10.2 2.2 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3784 PF12650.2 CBK20888.2 - 2.9 7.8 15.5 0.88 9.5 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) LRR_8 PF13855.1 CBK20889.2 - 0.025 14.3 2.6 0.085 12.6 0.4 2.7 2 1 0 2 2 2 0 Leucine rich repeat MORN PF02493.15 CBK20889.2 - 0.058 13.1 14.1 0.41 10.4 0.6 4.2 5 0 0 5 5 5 0 MORN repeat LRR_4 PF12799.2 CBK20889.2 - 0.069 12.7 0.2 0.069 12.7 0.1 2.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Nup96 PF12110.3 CBK20890.2 - 4.6e-20 71.9 0.1 6.2e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Rad60-SLD PF11976.3 CBK20891.2 - 0.011 15.3 0.2 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FAP PF07174.6 CBK20891.2 - 5.2 6.2 30.3 7.1 5.8 21.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Nuc_sug_transp PF04142.10 CBK20892.2 - 1.2e-07 31.0 4.8 2.1e-07 30.2 3.3 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter TraX PF05857.6 CBK20892.2 - 0.025 14.2 3.3 0.037 13.6 2.3 1.4 1 0 0 1 1 1 0 TraX protein EamA PF00892.15 CBK20892.2 - 0.029 14.3 0.2 0.029 14.3 0.1 2.8 2 1 1 3 3 3 0 EamA-like transporter family tRNA_anti-codon PF01336.20 CBK20893.2 - 1.1e-07 31.5 0.1 2.2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.17 CBK20895.2 - 2.7e-14 52.5 0.0 6.2e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20895.2 - 2e-11 43.6 0.0 5.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20895.2 - 1.3e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1319 PF07028.6 CBK20895.2 - 0.0016 18.6 8.5 0.14 12.3 4.1 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1319) RNase_T PF00929.19 CBK20895.2 - 0.13 12.5 2.4 0.79 9.9 0.3 2.4 1 1 1 2 2 2 0 Exonuclease CAP_GLY PF01302.20 CBK20896.2 - 1.4e-22 79.1 2.2 2.3e-22 78.4 1.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CBK20896.2 - 7.7e-22 77.3 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CBK20896.2 - 5.8e-06 25.6 0.0 6.2e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin family DUF563 PF04577.9 CBK20897.2 - 1.2e-19 71.0 0.0 2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Mpv17_PMP22 PF04117.7 CBK20897.2 - 4.3e-05 23.0 2.6 0.00016 21.2 1.5 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family Ribosomal_L1 PF00687.16 CBK20898.2 - 1e-46 159.0 5.9 1.2e-46 158.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Vps5 PF09325.5 CBK20899.2 - 8.6e-24 84.0 1.5 2e-23 82.8 1.0 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CBK20899.2 - 2.6e-22 78.7 0.2 5.9e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.13 CBK20899.2 - 8.4e-09 35.2 5.9 8.4e-09 35.2 4.1 1.9 2 0 0 2 2 2 1 BAR domain Clat_adaptor_s PF01217.15 CBK20900.2 - 7.6e-34 116.4 5.4 8.9e-34 116.2 3.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NADPH_Ox PF08414.5 CBK20900.2 - 0.0029 17.6 0.1 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase AP-5_subunit_s1 PF15001.1 CBK20900.2 - 0.053 13.4 0.2 0.25 11.2 0.0 1.7 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 FYVE PF01363.16 CBK20902.2 - 9.6e-19 67.0 9.7 9.6e-19 67.0 6.7 1.8 2 0 0 2 2 2 1 FYVE zinc finger F-box PF00646.28 CBK20902.2 - 0.011 15.4 0.3 0.036 13.7 0.2 2.0 1 0 0 1 1 1 0 F-box domain DBD_Tnp_Mut PF03108.10 CBK20902.2 - 0.014 14.9 2.5 0.07 12.7 0.1 2.4 2 0 0 2 2 2 0 MuDR family transposase FYVE_2 PF02318.11 CBK20902.2 - 0.66 9.8 6.7 1.8 8.4 4.7 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger HECT PF00632.20 CBK20903.2 - 6.5e-64 216.0 0.0 1.2e-63 215.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.21 CBK20904.2 - 1.6e-21 75.6 0.3 2.1e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF496 PF04363.7 CBK20904.2 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Mpv17_PMP22 PF04117.7 CBK20905.2 - 7.8e-19 67.0 4.3 7.8e-19 67.0 3.0 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.27 CBK20906.2 - 1.1e-25 88.4 7.4 3e-07 30.0 0.1 6.7 7 1 0 7 7 7 5 WD domain, G-beta repeat FYVE PF01363.16 CBK20907.2 - 1.8e-14 53.3 5.4 1.8e-14 53.3 3.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger ParBc_2 PF08857.6 CBK20907.2 - 0.12 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative ParB-like nuclease zf-RING_2 PF13639.1 CBK20907.2 - 1.3 8.9 10.8 1.2 8.9 4.2 2.3 2 0 0 2 2 2 0 Ring finger domain Toxin_38 PF14866.1 CBK20908.2 - 0.089 12.8 0.1 0.089 12.8 0.1 1.1 1 0 0 1 1 1 0 Potassium channel toxin Pkinase PF00069.20 CBK20909.2 - 1.3e-29 103.1 0.1 1.9e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK20909.2 - 6.1e-24 84.4 0.0 8.6e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK20909.2 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK20909.2 - 0.0061 16.3 0.0 0.066 12.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family UEV PF05743.8 CBK20909.2 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain Snf7 PF03357.16 CBK20911.2 - 1.8e-10 40.4 22.4 1.8e-10 40.4 15.5 1.8 1 1 1 2 2 2 1 Snf7 DUF948 PF06103.6 CBK20911.2 - 0.00091 19.0 10.6 0.0078 16.0 2.8 2.8 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 CBK20911.2 - 0.012 15.8 13.2 0.49 10.7 4.1 2.6 1 1 1 2 2 2 0 Spectrin repeat Erf4 PF10256.4 CBK20911.2 - 0.019 14.8 0.9 0.039 13.8 0.3 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF3813 PF12758.2 CBK20911.2 - 0.022 14.9 1.6 0.25 11.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) SPOUT_MTase_2 PF14419.1 CBK20911.2 - 0.04 13.1 0.3 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP TPR_20 PF14561.1 CBK20911.2 - 0.04 14.0 1.3 0.04 14.0 0.9 2.6 2 2 0 2 2 2 0 Tetratricopeptide repeat DUF4226 PF10774.4 CBK20911.2 - 0.066 13.2 7.0 0.38 10.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Reo_sigmaC PF04582.7 CBK20911.2 - 0.083 12.0 2.1 0.06 12.5 0.3 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CBK20911.2 - 0.54 10.0 18.9 0.48 10.1 7.8 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AnfG_VnfG PF03139.10 CBK20911.2 - 0.59 9.9 4.6 0.33 10.7 0.7 2.2 2 1 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit IncA PF04156.9 CBK20911.2 - 0.64 9.5 12.6 0.43 10.1 7.5 1.6 1 1 1 2 2 2 0 IncA protein Noelin-1 PF12308.3 CBK20911.2 - 0.93 9.3 13.8 1.5 8.6 0.5 3.3 1 1 2 3 3 3 0 Neurogenesis glycoprotein DUF2730 PF10805.3 CBK20911.2 - 1 9.1 8.3 0.12 12.0 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF883 PF05957.8 CBK20911.2 - 1.7 9.0 8.3 0.59 10.5 0.2 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Uteroglobin PF01099.12 CBK20911.2 - 1.7 8.4 7.9 18 5.2 0.1 3.4 3 0 0 3 3 3 0 Uteroglobin family Adenine_glyco PF03352.8 CBK20911.2 - 2 7.8 5.7 1.5 8.3 2.6 1.7 1 1 0 1 1 1 0 Methyladenine glycosylase PEP-utilisers_N PF05524.8 CBK20911.2 - 2.2 8.1 9.0 4.5 7.0 0.3 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Baculo_PEP_C PF04513.7 CBK20911.2 - 2.9 7.7 6.6 2 8.2 2.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.5 CBK20911.2 - 3.4 7.9 13.5 0.18 12.0 2.5 2.7 1 1 0 2 2 2 0 Tup N-terminal Rb_C PF08934.5 CBK20911.2 - 3.5 7.2 7.2 0.25 10.9 0.5 2.1 1 1 1 2 2 2 0 Rb C-terminal domain NPV_P10 PF05531.7 CBK20911.2 - 4 7.7 14.7 2.8 8.2 5.1 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.1 CBK20911.2 - 4.6 7.4 16.5 2.7 8.1 6.0 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF342 PF03961.8 CBK20911.2 - 5.4 5.3 15.0 0.8 8.0 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Baculo_p24 PF05073.7 CBK20911.2 - 7.5 6.0 10.6 67 2.9 7.4 2.1 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Mnd1 PF03962.10 CBK20911.2 - 8 6.0 18.0 19 4.8 8.8 2.2 1 1 1 2 2 2 0 Mnd1 family DUF2229 PF09989.4 CBK20911.2 - 8.9 5.7 9.0 2.3 7.6 0.2 2.1 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) PI3_PI4_kinase PF00454.22 CBK20912.2 - 2.5e-26 92.6 0.5 1.8e-25 89.8 0.3 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RCC1 PF00415.13 CBK20913.2 - 3.8e-21 75.0 9.9 2.6e-09 37.1 1.4 3.7 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK20913.2 - 1.9e-14 52.7 16.7 2.9e-07 29.9 2.2 2.2 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat TFCD_C PF12612.3 CBK20915.2 - 7.2e-08 32.0 1.5 7.6e-07 28.7 0.1 3.0 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CBK20915.2 - 0.0055 16.9 1.8 6.8 7.0 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats RRM_1 PF00076.17 CBK20916.2 - 1e-07 31.4 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20916.2 - 1.6e-06 27.9 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Orn_DAP_Arg_deC PF00278.17 CBK20917.2 - 2.1e-16 59.7 0.0 3.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mob1_phocein PF03637.12 CBK20918.2 - 2.7e-48 163.9 0.2 5.4e-48 162.9 0.2 1.5 1 0 0 1 1 1 1 Mob1/phocein family WBS_methylT PF12589.3 CBK20919.2 - 4e-15 56.0 3.5 6.2e-15 55.4 2.4 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CBK20919.2 - 1.4e-10 41.4 0.0 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK20919.2 - 2.1e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBK20919.2 - 4.9e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK20919.2 - 9.6e-05 22.9 0.2 0.0002 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK20919.2 - 0.00023 21.4 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK20919.2 - 0.00051 20.4 0.2 0.0016 18.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK20919.2 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain SMN PF06003.7 CBK20919.2 - 4.9 6.1 10.3 6.4 5.7 7.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1279 PF06916.8 CBK20920.2 - 5.8e-06 26.5 0.3 1.1e-05 25.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) GRP PF07172.6 CBK20920.2 - 7.2 7.1 20.2 2.3 8.7 11.5 1.9 2 0 0 2 2 2 0 Glycine rich protein family IBN_N PF03810.14 CBK20923.2 - 3.9e-14 52.3 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain CHD5 PF04420.9 CBK20923.2 - 0.013 15.1 0.4 0.043 13.4 0.1 2.1 1 1 0 1 1 1 0 CHD5-like protein HEAT_2 PF13646.1 CBK20923.2 - 0.017 15.4 0.1 0.043 14.1 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats Ribosomal_L22e PF01776.12 CBK20924.2 - 5.5e-18 65.0 0.0 6.4e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Caldesmon PF02029.10 CBK20925.2 - 0.022 13.1 17.4 0.031 12.7 12.1 1.3 1 0 0 1 1 1 0 Caldesmon C2 PF00168.25 CBK20926.2 - 2.6e-09 36.7 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF4436 PF14494.1 CBK20927.2 - 0.039 13.2 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Peptidase_S24 PF00717.18 CBK20928.2 - 4e-08 32.7 0.4 6.2e-08 32.1 0.3 1.4 1 1 0 1 1 1 1 Peptidase S24-like WD40 PF00400.27 CBK20929.2 - 1.8e-30 103.6 15.2 1.4e-09 37.4 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK20929.2 - 0.012 13.7 0.0 0.017 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ribosomal_L2_C PF03947.13 CBK20930.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK20930.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain zf-DHHC PF01529.15 CBK20931.2 - 1.3e-23 83.2 6.9 1.6e-23 82.9 4.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cys_rich_CPCC PF14206.1 CBK20931.2 - 2.1 7.9 6.8 1.4 8.4 3.5 1.7 2 0 0 2 2 2 0 Cysteine-rich CPCC ubiquitin PF00240.18 CBK20932.2 - 1e-34 117.7 0.7 1.4e-34 117.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.9 CBK20932.2 - 3.3e-27 93.9 6.3 5.6e-27 93.2 4.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.3 CBK20932.2 - 8.2e-20 70.2 0.7 1.2e-19 69.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CBK20932.2 - 8.6e-06 25.5 0.4 1.4e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Ubiquitin_2 PF14560.1 CBK20932.2 - 8.7e-06 25.9 0.1 2.9e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 CBK20932.2 - 8.5e-05 22.6 0.4 0.00015 21.8 0.3 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBK20932.2 - 0.0098 15.7 0.3 0.025 14.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CBK20932.2 - 0.045 13.7 0.3 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) AIG2 PF06094.7 CBK20932.2 - 0.087 13.3 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 AIG2-like family Plexin_cytopl PF08337.7 CBK20932.2 - 0.27 9.5 1.2 5.6 5.1 0.0 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain AAA_5 PF07728.9 CBK20935.2 - 3.4e-56 188.8 0.0 1.7e-13 50.4 0.0 7.7 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK20935.2 - 2.5e-14 53.5 0.4 0.043 13.9 0.0 6.8 5 2 0 5 5 5 3 AAA domain AAA_14 PF13173.1 CBK20935.2 - 1.4e-13 50.8 0.2 0.0067 16.3 0.0 6.0 5 0 0 5 5 5 3 AAA domain AAA_3 PF07726.6 CBK20935.2 - 1e-11 44.5 0.0 2.6e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBK20935.2 - 7.8e-08 31.9 0.0 0.004 16.6 0.0 4.7 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA PF00004.24 CBK20935.2 - 1.5e-06 28.4 0.0 0.036 14.2 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBK20935.2 - 0.00012 21.9 0.0 0.64 9.8 0.0 4.5 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CBK20935.2 - 0.00028 20.9 0.3 5.1 7.0 0.0 4.4 5 0 0 5 5 5 1 AAA ATPase domain VWA_2 PF13519.1 CBK20935.2 - 0.0013 18.8 0.0 0.004 17.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_19 PF13245.1 CBK20935.2 - 0.046 13.4 0.0 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBK20935.2 - 0.078 12.4 0.0 15 4.9 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBK20935.2 - 0.16 11.4 0.0 46 3.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain D-aminoacyl_C PF07908.7 CBK20935.2 - 2.7 7.3 0.0 6.2 6.2 0.0 1.6 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region AAA_17 PF13207.1 CBK20935.2 - 4.2 8.2 7.5 26 5.6 0.0 5.3 7 0 0 7 7 5 0 AAA domain FtsX PF02687.16 CBK20936.2 - 1.1e-13 50.9 15.7 1.1e-13 50.9 10.9 3.8 3 1 1 4 4 4 1 FtsX-like permease family IP_trans PF02121.13 CBK20937.2 - 1.1e-06 28.0 0.8 1.3e-06 27.7 0.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.13 CBK20938.2 - 7.9e-45 153.0 0.0 7.4e-44 149.8 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein UEV PF05743.8 CBK20939.2 - 7.6e-08 32.0 0.1 1.8e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 UEV domain EzrA PF06160.7 CBK20939.2 - 0.00056 18.2 0.3 0.00098 17.4 0.2 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA THOC7 PF05615.8 CBK20939.2 - 0.0028 17.9 1.2 0.0059 16.8 0.4 1.8 1 1 0 1 1 1 1 Tho complex subunit 7 HOOK PF05622.7 CBK20939.2 - 0.011 13.5 3.4 0.015 13.1 2.3 1.1 1 0 0 1 1 1 0 HOOK protein Alpha-2-MRAP_C PF06401.6 CBK20939.2 - 0.026 14.3 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain TPR_MLP1_2 PF07926.7 CBK20939.2 - 0.035 13.8 5.3 0.026 14.2 2.3 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 CBK20939.2 - 0.046 14.0 1.5 0.1 12.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) APG6 PF04111.7 CBK20939.2 - 0.053 12.5 3.1 0.085 11.8 2.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 CBK20939.2 - 0.061 12.5 4.0 0.78 8.9 3.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 CBK20939.2 - 0.081 12.9 7.6 1.2 9.1 2.1 3.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG bZIP_1 PF00170.16 CBK20939.2 - 0.084 12.8 0.7 0.084 12.8 0.5 2.3 2 1 1 3 3 3 0 bZIP transcription factor IncA PF04156.9 CBK20939.2 - 0.44 10.1 4.9 0.98 8.9 3.4 1.5 1 1 0 1 1 1 0 IncA protein DUF4215 PF13948.1 CBK20939.2 - 0.61 10.3 8.0 0.66 10.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) COG5 PF10392.4 CBK20939.2 - 0.89 9.5 4.6 0.21 11.5 0.5 1.9 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Glyco_transf_49 PF13896.1 CBK20940.2 - 0.022 13.8 1.2 0.023 13.7 0.7 1.2 1 1 0 1 1 1 0 Glycosyl-transferase for dystroglycan DUF3982 PF13138.1 CBK20940.2 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) HECT PF00632.20 CBK20941.2 - 6.3e-28 97.8 0.0 8.4e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Uteroglobin PF01099.12 CBK20941.2 - 0.0046 16.7 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Uteroglobin family Lectin_leg-like PF03388.8 CBK20942.2 - 1.1e-32 112.9 0.5 1.8e-32 112.3 0.3 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CBK20942.2 - 1.7e-07 30.8 2.3 5.1e-07 29.3 1.2 2.0 2 1 0 2 2 2 1 Legume lectin domain Lipase PF00151.14 CBK20942.2 - 0.065 12.4 0.3 0.099 11.8 0.2 1.2 1 0 0 1 1 1 0 Lipase IZUMO PF15005.1 CBK20942.2 - 1.3 9.0 4.3 3.2 7.7 2.6 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion CRAL_TRIO PF00650.15 CBK20943.2 - 2.8e-25 88.6 0.3 5.5e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBK20943.2 - 0.048 13.7 0.6 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain DUF1886 PF09171.5 CBK20943.2 - 0.061 12.3 1.0 0.4 9.6 0.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1886) Prp18 PF02840.10 CBK20944.2 - 5.5e-37 126.8 0.0 8.6e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain Xpo1 PF08389.7 CBK20945.2 - 0.004 17.0 0.6 0.012 15.5 0.3 1.9 2 0 0 2 2 2 1 Exportin 1-like protein Bromodomain PF00439.20 CBK20947.2 - 3.5e-11 42.8 0.0 9.5e-11 41.4 0.0 1.7 2 0 0 2 2 2 1 Bromodomain Mito_fiss_reg PF05308.6 CBK20950.2 - 0.64 9.3 4.3 0.81 9.0 2.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DNA_pol_B_2 PF03175.8 CBK20951.2 - 3.7e-07 29.1 10.8 0.0016 17.2 0.4 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral POR_N PF01855.14 CBK20953.2 - 3.2e-58 196.9 0.1 5.5e-58 196.1 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK20953.2 - 6.9e-26 91.1 0.4 1.5e-25 90.0 0.3 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 CBK20953.2 - 7e-11 41.5 0.0 1.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_16 PF13484.1 CBK20953.2 - 2.4e-09 37.7 5.7 0.00051 20.7 0.8 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.2 CBK20953.2 - 2.8e-09 37.2 6.5 2.8e-09 37.2 4.5 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 CBK20953.2 - 1.6e-08 34.2 0.2 4.6e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK20953.2 - 3.8e-08 32.6 18.7 1.3e-05 24.5 0.9 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 CBK20953.2 - 8.1e-07 29.2 10.8 0.0017 18.5 1.0 2.9 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK20953.2 - 6.5e-06 25.8 13.4 3.4e-05 23.5 8.2 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK20953.2 - 1.6e-05 24.8 11.2 0.0003 20.7 8.1 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.1 CBK20953.2 - 1.8e-05 24.5 14.0 0.0012 18.6 9.9 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK20953.2 - 2.8e-05 23.8 19.2 0.0002 21.0 2.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 CBK20953.2 - 0.00035 21.0 4.2 0.52 10.9 0.5 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 CBK20953.2 - 0.00086 19.5 11.9 0.003 17.8 7.0 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBK20953.2 - 0.0021 18.3 6.4 0.13 12.6 0.8 3.2 3 0 0 3 3 2 1 4Fe-4S single cluster domain Fer4_18 PF13746.1 CBK20953.2 - 0.0026 18.1 12.2 0.51 10.7 0.1 3.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK20953.2 - 0.0042 17.3 19.8 0.0093 16.2 1.3 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 CBK20953.2 - 0.0044 16.8 2.7 0.0044 16.8 1.9 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Transketolase_C PF02780.15 CBK20953.2 - 0.016 15.1 0.0 0.054 13.4 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glycos_transf_N PF04413.11 CBK20953.2 - 0.034 13.2 0.0 0.48 9.5 0.0 2.4 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) BrkDBD PF09607.5 CBK20953.2 - 0.11 12.0 0.3 0.8 9.3 0.1 2.4 2 0 0 2 2 2 0 Brinker DNA-binding domain RabGAP-TBC PF00566.13 CBK20954.2 - 2.9e-10 40.0 0.9 2.9e-10 40.0 0.6 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Baculo_PEP_C PF04513.7 CBK20954.2 - 0.87 9.4 9.4 0.46 10.3 2.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AbiH PF14253.1 CBK20954.2 - 6.8 6.2 8.8 1.9 8.0 1.3 2.1 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Lectin_leg-like PF03388.8 CBK20955.2 - 1.4e-37 129.0 0.9 1.8e-37 128.6 0.6 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CBK20955.2 - 5.7e-11 42.2 0.1 9.1e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Legume lectin domain PTEN_C2 PF10409.4 CBK20956.2 - 3e-09 36.6 0.0 4.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein ADP_ribosyl_GH PF03747.9 CBK20957.2 - 1.3e-55 189.2 0.4 1.5e-55 188.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MFS_1 PF07690.11 CBK20958.2 - 5.9e-09 35.0 8.5 7.4e-09 34.7 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Adeno_E3_14_5 PF04834.7 CBK20958.2 - 0.3 11.5 5.2 7.6 7.0 1.4 2.8 3 0 0 3 3 3 0 Early E3 14.5 kDa protein Pox_P21 PF05313.7 CBK20958.2 - 1.2 8.3 6.0 0.36 10.0 1.6 1.8 1 1 0 1 1 1 0 Poxvirus P21 membrane protein DUF4149 PF13664.1 CBK20958.2 - 6.2 6.9 9.0 8.6 6.4 1.4 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4149) Yip1 PF04893.12 CBK20958.2 - 6.4 6.2 15.8 12 5.3 6.9 2.5 1 1 1 2 2 2 0 Yip1 domain ubiquitin PF00240.18 CBK20960.2 - 1e-34 117.7 0.7 1.4e-34 117.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.9 CBK20960.2 - 3.3e-27 93.9 6.3 5.6e-27 93.2 4.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.3 CBK20960.2 - 8.2e-20 70.2 0.7 1.2e-19 69.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CBK20960.2 - 8.6e-06 25.5 0.4 1.4e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Ubiquitin_2 PF14560.1 CBK20960.2 - 8.7e-06 25.9 0.1 2.9e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 CBK20960.2 - 8.5e-05 22.6 0.4 0.00015 21.8 0.3 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBK20960.2 - 0.0098 15.7 0.3 0.025 14.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CBK20960.2 - 0.045 13.7 0.3 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) AIG2 PF06094.7 CBK20960.2 - 0.087 13.3 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 AIG2-like family Plexin_cytopl PF08337.7 CBK20960.2 - 0.27 9.5 1.2 5.6 5.1 0.0 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain PH PF00169.24 CBK20961.2 - 2.2e-16 59.9 0.1 2.4e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK20961.2 - 3.5e-07 30.4 3.7 1e-05 25.7 2.6 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBK20961.2 - 0.00016 21.6 0.1 0.00021 21.2 0.1 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 CBK20961.2 - 0.00099 18.9 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 CBK20961.2 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 CBK20961.2 - 0.0015 18.6 0.3 0.028 14.5 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Exo_endo_phos PF03372.18 CBK20963.2 - 2.3e-12 47.3 0.6 3.4e-12 46.8 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family cNMP_binding PF00027.24 CBK20963.2 - 2.4e-08 33.6 0.0 6.6e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Dymeclin PF09742.4 CBK20964.2 - 0.00013 20.2 0.1 0.00021 19.5 0.0 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Dymeclin PF09742.4 CBK20965.2 - 0.048 11.7 0.5 0.052 11.6 0.4 1.0 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Glyco_hydro_88 PF07470.8 CBK20965.2 - 0.061 12.3 0.1 0.063 12.3 0.1 1.0 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DUF2357 PF09823.4 CBK20965.2 - 0.1 11.6 0.6 0.11 11.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF427 PF04248.7 CBK20965.2 - 0.1 12.2 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF427) MORN_2 PF07661.8 CBK20966.2 - 4.8 7.5 8.6 20 5.6 0.7 3.7 3 0 0 3 3 3 0 MORN repeat variant He_PIG PF05345.7 CBK20967.2 - 0.0011 18.9 0.3 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 Putative Ig domain DUF2012 PF09430.5 CBK20968.2 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) DUF2997 PF11211.3 CBK20968.2 - 2 7.8 5.8 0.27 10.6 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) UEV PF05743.8 CBK20969.2 - 0.00053 19.6 0.1 0.00076 19.1 0.1 1.2 1 0 0 1 1 1 1 UEV domain zinc_ribbon_4 PF13717.1 CBK20969.2 - 0.1 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain CS PF04969.11 CBK20970.2 - 4.1e-08 33.6 0.0 1.2e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 CS domain DUF793 PF05633.6 CBK20970.2 - 0.015 14.0 1.7 0.022 13.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF793) DUF1682 PF07946.9 CBK20970.2 - 0.044 12.6 6.8 0.065 12.0 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GCN5L1 PF06320.8 CBK20970.2 - 0.11 12.3 7.7 0.029 14.1 2.8 1.9 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Maf1 PF09174.5 CBK20971.2 - 5.5e-23 81.7 0.4 6.5e-23 81.4 0.3 1.0 1 0 0 1 1 1 1 Maf1 regulator DnaB PF00772.16 CBK20971.2 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain TPR_11 PF13414.1 CBK20972.2 - 1e-58 194.8 23.9 1.4e-18 66.2 0.2 6.7 7 0 0 7 7 7 6 TPR repeat TPR_1 PF00515.23 CBK20972.2 - 3.6e-44 146.6 26.2 1.9e-07 30.4 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CBK20972.2 - 5.4e-39 128.9 19.5 2e-05 24.1 0.6 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 CBK20972.2 - 2.9e-24 83.2 13.8 9.3e-05 22.3 0.0 9.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBK20972.2 - 3e-19 69.1 15.7 2.5e-05 24.8 0.0 6.4 5 2 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBK20972.2 - 1.4e-16 60.1 20.8 4.4e-09 36.1 0.1 6.6 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBK20972.2 - 1.8e-15 55.4 23.1 0.0057 16.3 0.0 8.9 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBK20972.2 - 5.3e-14 51.4 8.2 0.23 12.1 0.0 9.1 4 3 6 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK20972.2 - 1.2e-10 41.5 8.3 0.00025 21.3 0.0 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK20972.2 - 1.1e-09 38.0 4.3 0.02 14.7 0.2 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3147 PF11345.3 CBK20972.2 - 2.1e-06 27.7 23.0 2.4e-06 27.5 5.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3147) TPR_7 PF13176.1 CBK20972.2 - 8.2e-06 25.2 5.7 3.9 7.5 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBK20972.2 - 2.4e-05 24.3 1.4 1.3 9.2 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF2360 PF10152.4 CBK20972.2 - 0.0092 16.2 10.8 0.64 10.2 4.6 2.5 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein (DUF2360) Fis1_TPR_C PF14853.1 CBK20972.2 - 0.039 13.8 6.7 3.6 7.5 0.0 4.4 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 CBK20972.2 - 0.56 10.5 8.0 3.7 7.8 0.0 4.0 2 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CBK20972.2 - 0.67 9.9 0.0 0.67 9.9 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF1129 PF06570.6 CBK20972.2 - 0.84 8.9 7.2 0.19 11.0 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MIT PF04212.13 CBK20972.2 - 1.6 8.6 15.9 0.95 9.3 0.1 5.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Hum_adeno_E3A PF05393.6 CBK20972.2 - 4.3 7.0 7.8 18 5.0 5.4 2.1 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein RRM_1 PF00076.17 CBK20974.2 - 3.1e-29 100.3 2.6 2e-14 52.9 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK20974.2 - 5.3e-20 71.1 0.1 2.6e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK20974.2 - 1e-12 47.6 0.6 8.2e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBK20974.2 - 1.8e-05 24.6 0.1 0.00062 19.7 0.0 2.4 2 0 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.1 CBK20974.2 - 0.0022 17.7 0.0 0.059 13.1 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBK20974.2 - 0.0037 17.1 0.2 0.027 14.3 0.1 2.2 2 1 0 2 2 2 1 RNA binding motif HATPase_c PF02518.21 CBK20974.2 - 0.013 15.1 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OB_RNB PF08206.6 CBK20974.2 - 0.023 14.2 0.5 8.5 5.9 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Clathrin PF00637.15 CBK20976.2 - 2.1e-08 33.8 4.2 3.7e-05 23.3 0.0 4.0 4 1 0 4 4 4 2 Region in Clathrin and VPS Vps39_1 PF10366.4 CBK20976.2 - 4.4e-05 23.4 3.2 0.00014 21.8 0.3 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CBK20976.2 - 0.0064 16.6 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_11 PF13414.1 CBK20976.2 - 0.055 13.1 0.1 0.6 9.8 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 CBK20976.2 - 0.071 12.7 0.0 1.5 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.17 CBK20977.2 - 2.9e-14 52.3 0.7 2.9e-14 52.3 0.5 1.6 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 CBK20977.2 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain PAP2_C PF14360.1 CBK20978.2 - 7.6e-17 61.3 3.2 7.6e-17 61.3 2.2 3.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 CBK20978.2 - 2.6e-07 30.3 1.7 2.6e-07 30.3 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 CBK20978.2 - 0.0096 15.5 3.1 0.0096 15.5 2.2 2.6 2 0 0 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 CBK20978.2 - 6.1 6.2 15.9 2.9 7.2 2.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) ATP-grasp_5 PF13549.1 CBK20979.2 - 2.3e-58 197.0 0.6 3.7e-58 196.3 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CBK20979.2 - 8.1e-39 132.3 0.0 1.1e-37 128.6 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK20979.2 - 1.7e-22 79.7 0.1 4.3e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 CBK20979.2 - 9.1e-10 38.9 2.5 2.5e-09 37.5 1.8 1.8 1 0 0 1 1 1 1 CoA binding domain mIF3 PF14877.1 CBK20979.2 - 0.035 13.4 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Prefoldin PF02996.12 CBK20980.2 - 4.9e-12 45.5 2.8 6.9e-12 45.0 2.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF489 PF04356.7 CBK20980.2 - 0.047 13.2 6.0 0.08 12.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Prefoldin_2 PF01920.15 CBK20980.2 - 0.7 9.6 8.0 22 4.8 5.5 2.3 1 1 0 1 1 1 0 Prefoldin subunit AAA PF00004.24 CBK20981.2 - 5.9e-13 49.1 0.2 2.6e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CBK20981.2 - 9.4e-07 28.8 0.0 2.4e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RuvB_N PF05496.7 CBK20981.2 - 1.5e-06 27.4 0.0 2.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 CBK20981.2 - 1.1e-05 24.3 0.1 1.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CBK20981.2 - 3.6e-05 24.5 0.2 0.00013 22.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBK20981.2 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBK20981.2 - 0.00013 21.1 0.1 0.00038 19.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CBK20981.2 - 0.00018 21.5 0.4 0.0022 18.0 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CBK20981.2 - 0.00028 20.5 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBK20981.2 - 0.0004 20.2 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBK20981.2 - 0.00043 19.2 0.0 0.00068 18.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 CBK20981.2 - 0.00043 19.9 0.1 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBK20981.2 - 0.00077 19.2 0.9 0.002 17.8 0.1 2.2 2 1 0 2 2 2 1 NTPase RNA_helicase PF00910.17 CBK20981.2 - 0.00084 19.4 0.0 0.0023 18.0 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CBK20981.2 - 0.00093 19.5 0.1 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK20981.2 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBK20981.2 - 0.0076 16.2 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBK20981.2 - 0.0081 14.9 0.0 0.037 12.7 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 CBK20981.2 - 0.027 14.1 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CBK20981.2 - 0.031 14.3 0.0 0.38 10.7 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.24 CBK20981.2 - 0.033 13.6 0.1 7.5 6.0 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase PTCB-BRCT PF12738.2 CBK20981.2 - 0.047 13.5 0.0 0.21 11.4 0.0 2.2 3 0 0 3 3 1 0 twin BRCT domain SKI PF01202.17 CBK20981.2 - 0.063 13.1 0.2 0.26 11.1 0.0 2.1 2 1 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.22 CBK20981.2 - 0.067 13.4 1.4 0.21 11.8 0.1 2.4 1 1 1 2 2 2 0 ABC transporter NACHT PF05729.7 CBK20981.2 - 0.15 11.7 0.1 0.38 10.3 0.0 2.0 2 1 0 2 2 1 0 NACHT domain RecX PF02631.11 CBK20982.2 - 0.033 14.3 4.5 0.042 14.0 3.1 1.1 1 0 0 1 1 1 0 RecX family DUF4635 PF15466.1 CBK20982.2 - 0.1 11.8 1.1 0.12 11.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) G6PD_bact PF10786.4 CBK20982.2 - 0.13 11.7 1.1 0.15 11.4 0.8 1.0 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) E1_dh PF00676.15 CBK20982.2 - 0.22 10.2 4.5 0.32 9.6 3.1 1.4 1 1 0 1 1 1 0 Dehydrogenase E1 component Seryl_tRNA_N PF02403.17 CBK20982.2 - 0.33 11.0 7.5 0.3 11.1 4.6 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 CBK20982.2 - 0.78 9.3 8.4 0.84 9.2 5.8 1.1 1 0 0 1 1 1 0 Mnd1 family PBP_sp32 PF07222.7 CBK20982.2 - 2 7.5 6.1 2.1 7.4 4.2 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_60s PF00428.14 CBK20983.2 - 7.2e-16 58.3 15.1 8.3e-16 58.1 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3381 PF11861.3 CBK20983.2 - 0.0021 17.5 0.6 0.003 17.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Myc_N PF01056.13 CBK20983.2 - 0.023 13.8 4.5 0.025 13.7 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region AF1Q PF15017.1 CBK20983.2 - 0.034 14.0 1.5 0.043 13.7 1.1 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 CBK20983.2 - 0.085 12.3 3.6 0.099 12.1 2.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 CBK20983.2 - 0.14 11.4 7.2 0.13 11.5 5.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.3 CBK20983.2 - 0.2 11.5 6.3 0.18 11.6 4.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Shadoo PF14999.1 CBK20983.2 - 0.26 11.1 2.1 0.31 10.9 1.5 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Sigma70_ner PF04546.8 CBK20983.2 - 0.33 10.5 5.9 0.32 10.5 4.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytomega_UL84 PF06284.6 CBK20983.2 - 0.41 9.0 2.0 0.42 8.9 1.4 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein OCC1 PF15506.1 CBK20983.2 - 0.72 9.7 3.1 0.97 9.3 2.2 1.2 1 0 0 1 1 1 0 OCC1 family DUF3824 PF12868.2 CBK20983.2 - 0.73 10.7 4.2 0.9 10.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GMP_synt_C PF00958.17 CBK20984.2 - 2.9e-38 129.4 0.1 7.9e-38 128.0 0.0 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CBK20984.2 - 1.3e-35 122.6 0.1 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CBK20984.2 - 8.2e-10 37.9 0.1 9.4e-06 24.7 0.1 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CBK20984.2 - 2.5e-07 30.3 0.1 9.9e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 CBK20984.2 - 0.00079 18.0 0.3 0.0031 16.1 0.1 1.8 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 CBK20984.2 - 0.0034 16.8 0.0 0.0079 15.6 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) SNO PF01174.14 CBK20984.2 - 0.0064 16.1 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Asn_synthase PF00733.16 CBK20984.2 - 0.015 14.7 0.1 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.8 CBK20984.2 - 0.019 14.2 0.0 0.96 8.6 0.0 2.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Alg6_Alg8 PF03155.10 CBK20985.2 - 4.4e-123 411.5 26.6 5.4e-123 411.2 18.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 CBK20985.2 - 4.4e-06 26.3 4.9 4.4e-06 26.3 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) LRR_8 PF13855.1 CBK20986.2 - 9.2e-06 25.3 6.9 0.14 11.9 0.0 4.8 3 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 CBK20986.2 - 0.0012 18.3 16.9 0.88 9.2 0.0 6.5 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) NAC PF01849.13 CBK20986.2 - 0.056 12.9 0.0 0.68 9.5 0.3 2.3 2 0 0 2 2 2 0 NAC domain DNA_pol_B_2 PF03175.8 CBK20987.2 - 1e-06 27.7 11.9 0.0062 15.2 8.3 3.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.8 CBK20988.2 - 1e-07 30.9 9.5 0.016 13.8 0.0 3.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral He_PIG PF05345.7 CBK20989.2 - 6.7e-18 64.4 26.1 4.2e-05 23.4 0.1 5.2 5 0 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK20989.2 - 0.00076 19.2 6.6 2 8.2 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain IncA PF04156.9 CBK20989.2 - 0.009 15.6 0.3 0.014 15.0 0.2 1.2 1 0 0 1 1 1 1 IncA protein PIRT PF15099.1 CBK20989.2 - 0.015 14.5 0.0 0.049 12.8 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Mg_trans_NIPA PF05653.9 CBK20989.2 - 0.044 12.7 0.4 3 6.7 0.2 2.4 2 0 0 2 2 2 0 Magnesium transporter NIPA DUF4097 PF13349.1 CBK20989.2 - 0.092 12.2 1.8 0.27 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) HRM PF02793.17 CBK20989.2 - 0.11 12.5 11.2 7.2 6.6 0.0 5.2 5 0 0 5 5 5 0 Hormone receptor domain PKD PF00801.15 CBK20989.2 - 0.7 9.6 0.0 0.7 9.6 0.0 3.8 6 0 0 6 6 6 0 PKD domain DUF3185 PF11381.3 CBK20989.2 - 5.7 6.7 10.4 16 5.3 7.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Peptidase_S8 PF00082.17 CBK20990.2 - 5.1e-41 140.6 1.5 6.3e-41 140.3 1.0 1.1 1 0 0 1 1 1 1 Subtilase family PAP2_C PF14360.1 CBK20991.2 - 1.9e-16 60.0 1.4 1.9e-16 60.0 1.0 3.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 CBK20991.2 - 4.3e-07 29.6 1.5 9.8e-07 28.4 1.0 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 CBK20991.2 - 6.5e-06 25.8 5.7 6.5e-06 25.8 3.9 2.7 2 1 1 3 3 3 1 PAP2 superfamily Peptidase_M50B PF13398.1 CBK20991.2 - 0.55 9.5 10.0 2.9 7.2 0.6 3.0 3 0 0 3 3 3 0 Peptidase M50B-like RDD PF06271.7 CBK20991.2 - 3.9 7.3 15.2 0.15 11.9 3.1 2.5 2 1 0 2 2 2 0 RDD family DUF1516 PF07457.6 CBK20991.2 - 6 6.9 7.7 0.44 10.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) Vip3A_N PF12495.3 CBK20992.2 - 0.27 10.8 6.3 1 9.0 0.1 2.4 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal UPF0242 PF06785.6 CBK20992.2 - 1.9 7.0 11.2 0.13 10.9 1.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) DUF1183 PF06682.7 CBK20993.2 - 3.3e-51 174.7 0.2 4.2e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) NVEALA PF14055.1 CBK20993.2 - 0.19 11.4 2.1 0.33 10.6 1.4 1.6 1 1 0 1 1 1 0 NVEALA protein zf-NF-X1 PF01422.12 CBK20994.2 - 6.7e-13 48.2 279.3 2.1e-06 27.5 8.7 16.5 16 0 0 16 16 16 11 NF-X1 type zinc finger MORN PF02493.15 CBK20995.2 - 5.4e-07 28.9 35.5 3.1e-06 26.5 0.8 6.0 6 1 0 6 6 6 4 MORN repeat MORN_2 PF07661.8 CBK20995.2 - 0.015 15.2 14.4 3.4 7.9 1.1 4.4 3 0 0 3 3 3 0 MORN repeat variant VASP_tetra PF08776.6 CBK20995.2 - 0.042 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain P12 PF12669.2 CBK20996.2 - 0.0022 18.1 0.2 0.0038 17.4 0.2 1.3 1 0 0 1 1 1 1 Virus attachment protein p12 family DUF350 PF03994.9 CBK20996.2 - 0.013 15.1 0.1 0.013 15.1 0.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) CcmH PF03918.9 CBK20996.2 - 0.02 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3098 PF11297.3 CBK20996.2 - 0.072 12.8 0.1 0.072 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) DUF3357 PF11837.3 CBK20996.2 - 0.072 12.9 0.0 9.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) OSTbeta PF15048.1 CBK20996.2 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2754 PF10953.3 CBK20996.2 - 0.14 12.2 0.3 0.14 12.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF3827 PF12877.2 CBK20996.2 - 0.15 10.1 0.5 0.2 9.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ABC2_membrane_3 PF12698.2 CBK20996.2 - 0.7 8.8 3.5 0.27 10.2 0.2 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein XPG_I PF00867.13 CBK20997.2 - 6.2e-26 90.2 0.0 2e-25 88.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CBK20997.2 - 0.003 17.0 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 CBK20998.2 - 2.3e-29 101.5 0.0 3.3e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain XRN_N PF03159.13 CBK20998.2 - 2e-05 24.0 0.0 2.3e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PS_Dcarbxylase PF02666.10 CBK20999.2 - 2.2e-55 187.0 0.0 3.6e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Fe-ADH PF00465.14 CBK21000.2 - 5.6e-72 242.3 0.0 6.3e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK21000.2 - 8.6e-12 44.8 0.1 4.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CbiK PF06180.6 CBK21000.2 - 0.0043 16.1 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) DHQ_synthase PF01761.15 CBK21000.2 - 0.014 14.3 0.1 0.085 11.7 0.0 2.2 2 0 0 2 2 2 0 3-dehydroquinate synthase HSP70 PF00012.15 CBK21001.2 - 8.1e-67 225.4 2.8 9.1e-67 225.3 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21001.2 - 4.3e-12 45.2 0.4 3.8e-11 42.1 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK21001.2 - 0.0019 18.0 6.8 0.0022 17.8 1.3 3.0 2 2 0 2 2 2 1 Cell division protein FtsA E1-E2_ATPase PF00122.15 CBK21002.2 - 1.3e-65 220.6 0.4 2.1e-64 216.7 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK21002.2 - 1.4e-48 164.8 0.3 1.4e-48 164.8 0.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK21002.2 - 1.8e-30 106.9 0.0 7.4e-30 104.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBK21002.2 - 1.3e-16 59.7 0.4 5.9e-16 57.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBK21002.2 - 2.2e-15 56.3 0.0 4.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBK21002.2 - 1.6e-13 51.2 0.0 6.2e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK21002.2 - 8.5e-05 22.2 0.8 0.00031 20.4 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ADK PF00406.17 CBK21003.2 - 5.6e-27 94.4 0.0 7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBK21003.2 - 7.1e-06 25.5 6.1 3.8e-05 23.2 4.2 2.0 1 1 0 1 1 1 1 Adenylate kinase, active site lid GFA PF04828.9 CBK21003.2 - 0.0041 17.0 0.1 0.43 10.5 0.0 2.2 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 CBK21003.2 - 0.053 12.9 1.1 10 5.7 0.3 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C4_Topoisom PF01396.14 CBK21003.2 - 0.13 11.8 0.6 20 4.7 0.0 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger CENP-F_leu_zip PF10473.4 CBK21004.2 - 0.0019 18.0 14.5 0.0019 18.0 10.1 3.4 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gp58 PF07902.6 CBK21004.2 - 0.0057 14.9 11.1 0.0071 14.6 7.7 1.2 1 0 0 1 1 1 1 gp58-like protein GAS PF13851.1 CBK21004.2 - 0.011 14.9 42.7 0.78 8.8 3.5 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 CBK21004.2 - 0.99 6.6 49.2 0.013 12.8 23.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 CBK21004.2 - 3 7.2 41.5 0.23 10.8 9.7 3.3 1 1 1 2 2 2 0 Intermediate filament protein FlxA PF14282.1 CBK21004.2 - 3.2 7.7 47.8 2.5 8.0 11.7 3.8 1 1 3 4 4 4 0 FlxA-like protein Reo_sigmaC PF04582.7 CBK21004.2 - 3.8 6.6 15.4 1 8.5 2.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF464 PF04327.7 CBK21004.2 - 4 7.7 8.6 46 4.3 0.7 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF464) APG6 PF04111.7 CBK21004.2 - 7.7 5.4 45.4 3.4 6.6 8.1 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 COG6 PF06419.6 CBK21005.2 - 1.1e-40 139.3 16.8 1.2e-30 106.2 4.3 2.9 2 1 0 2 2 2 2 Conserved oligomeric complex COG6 LRR_8 PF13855.1 CBK21006.2 - 9.8e-09 34.8 4.2 1.7 8.4 0.1 6.8 6 2 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 CBK21006.2 - 0.0022 17.5 13.9 2.3 7.9 0.0 8.1 6 3 2 8 8 8 1 Leucine Rich repeats (2 copies) RRM_1 PF00076.17 CBK21007.2 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21007.2 - 0.00052 19.9 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21007.2 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.6 CBK21008.2 - 1.1e-36 126.4 0.1 8.8e-35 120.1 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CBK21008.2 - 0.00012 21.8 2.6 0.0053 16.5 0.4 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.17 CBK21008.2 - 0.00067 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21008.2 - 0.0017 18.2 0.0 0.0066 16.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21008.2 - 0.028 14.2 0.0 0.091 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_efflux PF01545.16 CBK21009.2 - 1.9e-65 220.7 5.2 2.3e-65 220.5 3.6 1.0 1 0 0 1 1 1 1 Cation efflux family Aa_trans PF01490.13 CBK21010.2 - 4.7e-30 104.4 24.8 5.2e-30 104.2 17.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2435 PF10363.4 CBK21011.2 - 2.8e-16 59.2 1.0 3.4e-15 55.7 0.1 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 CBK21011.2 - 6e-06 26.4 6.3 0.014 15.6 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBK21011.2 - 3.7e-05 23.4 4.3 0.12 12.5 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 CBK21011.2 - 0.0027 16.1 0.6 0.017 13.5 0.1 2.1 2 0 0 2 2 2 1 Adaptin N terminal region ParcG PF10274.4 CBK21011.2 - 0.022 14.6 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT_EZ PF13513.1 CBK21011.2 - 0.023 15.1 6.4 0.19 12.2 0.1 4.0 2 2 2 4 4 4 0 HEAT-like repeat DUF2411 PF10304.4 CBK21011.2 - 0.053 13.0 0.2 0.17 11.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Cnd1 PF12717.2 CBK21011.2 - 0.079 12.8 1.1 12 5.7 0.0 3.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Sugar_tr PF00083.19 CBK21012.2 - 8.1e-37 126.8 20.3 7.1e-36 123.7 14.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBK21012.2 - 2.6e-12 46.1 18.5 3.6e-12 45.6 12.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CBK21012.2 - 2.6e-05 22.8 20.4 0.0065 14.9 9.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Ribosomal_L30 PF00327.15 CBK21013.2 - 2.5e-21 75.0 1.3 5.6e-21 73.8 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBK21013.2 - 5.2e-13 48.8 7.2 1e-12 47.8 5.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L19e PF01280.15 CBK21015.2 - 2.1e-56 189.8 11.7 2.7e-56 189.4 8.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e PP2C PF00481.16 CBK21016.2 - 4.9e-33 114.5 0.0 7.8e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBK21016.2 - 1.7e-08 34.0 0.0 7.2e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C FBA PF04300.8 CBK21016.2 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box associated region Thymidylate_kin PF02223.12 CBK21017.2 - 3.2e-45 153.7 0.0 3.6e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase PRK PF00485.13 CBK21017.2 - 0.00019 21.0 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.1 CBK21017.2 - 0.0035 16.0 0.0 0.0041 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 CBK21017.2 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBK21017.2 - 0.0063 16.2 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 CBK21017.2 - 0.1 12.7 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF3316 PF11777.3 CBK21019.2 - 0.0054 16.4 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3316) WHIM3 PF15614.1 CBK21019.2 - 0.073 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 NTF2 PF02136.15 CBK21020.2 - 3.7e-12 46.6 0.0 4.3e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Adaptin_N PF01602.15 CBK21021.2 - 7.3e-130 433.7 9.5 8.6e-130 433.5 6.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK21021.2 - 1.1e-23 84.0 3.8 6.4e-21 74.9 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK21021.2 - 8.3e-17 61.2 2.9 9.3e-06 25.8 0.0 5.1 3 2 1 4 4 4 4 HEAT repeats HEAT PF02985.17 CBK21021.2 - 5.4e-10 38.4 11.0 0.26 11.4 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.2 CBK21021.2 - 5.4e-07 28.8 1.9 1.3e-05 24.3 0.3 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CBK21021.2 - 7.6e-05 23.0 3.7 0.26 11.8 0.0 5.0 4 2 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 CBK21021.2 - 0.00012 21.5 0.1 0.15 11.3 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 CBK21021.2 - 0.0052 16.5 0.6 8.9 6.3 0.0 4.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CBK21021.2 - 0.09 13.2 0.1 13 6.6 0.0 3.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat TFIIA PF03153.8 CBK21021.2 - 0.47 10.2 4.9 0.66 9.8 3.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 CBK21021.2 - 0.63 7.8 11.6 1.4 6.7 8.0 1.5 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 CBK21021.2 - 0.72 9.3 11.8 1.4 8.4 8.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_M24 PF00557.19 CBK21022.2 - 3e-49 167.4 0.1 4.3e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CBK21022.2 - 1.1e-33 115.5 0.0 2.4e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain C2 PF00168.25 CBK21024.2 - 0.017 14.9 0.1 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain MazG PF03819.12 CBK21026.2 - 2.8e-07 30.3 0.0 1.2e-06 28.3 0.0 2.0 1 1 1 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MitMem_reg PF13012.1 CBK21027.2 - 2.4e-20 72.7 2.3 2.6e-20 72.6 0.5 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CBK21027.2 - 5.9e-17 61.4 0.2 1.4e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HJURP_C PF12347.3 CBK21027.2 - 0.086 12.4 0.9 0.6 9.7 0.0 2.7 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat DUF2465 PF10239.4 CBK21027.2 - 0.088 12.0 2.8 0.088 12.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) CUE PF02845.11 CBK21027.2 - 0.095 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 CUE domain WD40 PF00400.27 CBK21028.2 - 3.7e-30 102.6 7.1 1.9e-07 30.7 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CBK21028.2 - 2.4e-05 22.6 2.4 0.039 12.1 0.1 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK21028.2 - 0.00046 19.0 1.3 0.16 10.6 0.1 3.3 2 2 1 3 3 3 2 Nup133 N terminal like Hira PF07569.6 CBK21028.2 - 0.022 13.9 0.6 1.1 8.4 0.0 3.1 1 1 2 3 3 3 0 TUP1-like enhancer of split Adap_comp_sub PF00928.16 CBK21028.2 - 0.039 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Nbas_N PF15492.1 CBK21028.2 - 0.055 12.5 0.0 2.9 6.9 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ras PF00071.17 CBK21029.2 - 8.6e-50 168.2 0.5 9.8e-50 168.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK21029.2 - 4.8e-18 65.7 0.1 8.3e-18 65.0 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK21029.2 - 4.7e-13 48.7 0.1 6.1e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK21029.2 - 2.6e-06 26.7 0.2 3.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK21029.2 - 3.8e-05 23.6 0.1 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK21029.2 - 0.0002 20.6 0.1 0.007 15.5 0.0 2.0 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CBK21029.2 - 0.05 13.3 0.0 0.083 12.5 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 CBK21029.2 - 0.051 13.7 0.0 0.078 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBK21029.2 - 0.084 12.0 0.0 0.36 10.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CBK21029.2 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBK21029.2 - 0.13 11.4 0.0 0.21 10.8 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B eIF-5_eIF-2B PF01873.12 CBK21030.2 - 4.4e-32 110.3 0.0 7e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF3797 PF12677.2 CBK21030.2 - 0.017 14.7 3.2 0.42 10.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Lar_restr_allev PF14354.1 CBK21030.2 - 0.021 15.1 0.6 0.051 13.8 0.1 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar SelP_N PF04592.9 CBK21030.2 - 0.039 13.3 8.2 0.061 12.7 5.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RP-C_C PF11800.3 CBK21030.2 - 0.092 12.4 1.3 0.15 11.7 0.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Ndc1_Nup PF09531.5 CBK21030.2 - 0.1 10.9 0.9 0.13 10.7 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BSMAP PF12280.3 CBK21030.2 - 0.19 11.5 3.7 0.3 10.9 2.6 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein zf-LITAF-like PF10601.4 CBK21030.2 - 0.23 11.3 2.8 0.45 10.4 1.9 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF2387 PF09526.5 CBK21030.2 - 0.36 10.7 6.1 2.1 8.3 4.2 2.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zip PF02535.17 CBK21030.2 - 0.46 9.4 3.2 0.52 9.2 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 CBK21030.2 - 3 7.6 5.2 4.5 7.0 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IBN_N PF03810.14 CBK21031.2 - 0.00017 21.4 7.3 0.0012 18.6 0.0 4.5 4 1 1 5 5 5 1 Importin-beta N-terminal domain HEAT PF02985.17 CBK21031.2 - 0.019 15.0 0.2 0.31 11.2 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat Peptidase_C1 PF00112.18 CBK21032.2 - 3.6e-70 236.2 2.1 7.7e-70 235.1 1.5 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK21032.2 - 4.1e-09 36.5 4.9 1e-08 35.3 3.4 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) V_ATPase_I PF01496.14 CBK21033.2 - 0.00077 17.4 10.8 0.00077 17.4 7.5 4.2 1 1 2 4 4 4 2 V-type ATPase 116kDa subunit family Filament PF00038.16 CBK21033.2 - 0.0083 15.6 9.1 0.0083 15.6 6.3 6.7 3 3 3 6 6 6 3 Intermediate filament protein TUDOR PF00567.19 CBK21033.2 - 0.0096 15.7 1.6 0.035 13.9 0.1 2.8 2 0 0 2 2 2 1 Tudor domain DUF972 PF06156.8 CBK21033.2 - 0.016 15.5 3.8 0.016 15.5 2.7 8.5 6 2 2 9 9 9 0 Protein of unknown function (DUF972) IncA PF04156.9 CBK21033.2 - 1.4 8.4 108.7 0.015 14.8 16.3 7.1 3 3 3 6 6 6 0 IncA protein HSP20 PF00011.16 CBK21034.2 - 2.6e-12 46.4 0.0 2.8e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Mito_carr PF00153.22 CBK21035.2 - 1.8e-58 194.2 2.8 3.4e-19 68.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sulf_transp PF04143.9 CBK21036.2 - 1.7e-05 24.7 26.4 0.00026 20.9 5.9 3.2 2 1 1 3 3 3 2 Sulphur transport DUF3382 PF11862.3 CBK21036.2 - 0.0067 16.3 5.0 0.24 11.3 0.2 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF3382) DUF1182 PF06681.8 CBK21036.2 - 0.11 11.6 1.7 0.24 10.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) IF-2B PF01008.12 CBK21038.2 - 2.2e-37 128.5 0.0 2.7e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF676 PF05057.9 CBK21039.2 - 3.8e-21 75.3 0.0 6.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CBK21039.2 - 0.0042 16.7 0.1 0.013 15.1 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CBK21039.2 - 0.013 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RanBP PF00641.13 CBK21039.2 - 0.13 11.3 3.0 0.29 10.2 2.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Phosphodiest PF01663.17 CBK21040.2 - 0.0013 18.0 2.9 0.0025 17.2 0.2 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CBK21040.2 - 0.02 14.0 0.3 0.043 13.0 0.2 1.6 1 1 0 1 1 1 0 Sulfatase Alpha-amylase PF00128.19 CBK21041.2 - 1.5e-05 24.5 0.0 0.00036 20.0 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CBK21041.2 - 0.0002 21.3 0.0 0.00069 19.6 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Y_phosphatase PF00102.22 CBK21042.2 - 4.6e-07 29.4 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBK21042.2 - 5.8e-06 26.6 0.0 7.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 CBK21042.2 - 0.00032 20.1 0.0 0.00076 18.9 0.0 1.7 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CBK21042.2 - 0.0013 18.8 0.0 0.0033 17.4 0.0 1.6 1 1 1 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 CBK21042.2 - 0.0043 16.6 0.0 0.0055 16.2 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 CBK21042.2 - 0.019 14.3 0.9 0.037 13.4 0.6 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family YjeF_N PF03853.10 CBK21042.2 - 0.092 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ribosomal_L29 PF00831.18 CBK21044.2 - 6.9e-18 64.0 1.1 6.9e-18 64.0 0.7 2.2 1 1 1 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CBK21044.2 - 0.014 15.5 7.0 0.023 14.9 4.9 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF382 PF04037.8 CBK21044.2 - 0.046 13.5 1.7 0.068 12.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) tRNA-synt_1c PF00749.16 CBK21046.2 - 2e-105 351.9 0.0 2.8e-105 351.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBK21046.2 - 1.2e-36 125.9 0.0 2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CBK21047.2 - 7.6e-25 87.3 0.0 1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 ArfGap PF01412.13 CBK21048.2 - 1.2e-37 128.2 7.8 7e-37 125.7 5.4 2.1 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf PMM PF03332.8 CBK21049.2 - 3e-74 249.3 0.6 3.6e-74 249.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Corona_nucleoca PF00937.13 CBK21050.2 - 0.22 10.4 14.2 0.36 9.7 9.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1777 PF08648.7 CBK21050.2 - 0.46 10.1 16.2 0.86 9.3 11.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CENP-F_leu_zip PF10473.4 CBK21051.2 - 0.73 9.6 41.3 0.15 11.9 9.3 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 CBK21051.2 - 2 6.7 24.9 3.4 6.0 17.3 1.3 1 0 0 1 1 1 0 AAA domain PilJ PF13675.1 CBK21051.2 - 4.4 7.6 17.4 0.55 10.5 4.2 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF948 PF06103.6 CBK21051.2 - 6.3 6.7 9.9 0.88 9.4 1.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Bac_rhamnosid_N PF08531.5 CBK21052.2 - 0.061 12.8 0.5 3.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Alpha-L-rhamnosidase N-terminal domain AhpC-TSA PF00578.16 CBK21053.2 - 1.1e-35 122.0 0.0 1.4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK21053.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK21053.2 - 2.7e-11 42.9 0.0 5.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kinesin PF00225.18 CBK21054.2 - 5.1e-27 94.4 0.0 8.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_30 PF13604.1 CBK21054.2 - 0.058 12.9 0.0 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain zinc_ribbon_5 PF13719.1 CBK21054.2 - 0.061 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBK21054.2 - 0.082 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.27 CBK21055.2 - 1.1e-07 31.4 6.1 0.001 18.8 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat E2F_TDP PF02319.15 CBK21056.2 - 1.2e-14 53.5 0.4 3.2e-08 33.0 0.0 2.5 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.6 CBK21056.2 - 0.15 11.7 0.5 21 4.8 0.0 2.5 2 0 0 2 2 2 0 CDC6, C terminal WD40 PF00400.27 CBK21057.2 - 5.5e-17 60.9 0.1 5.9e-07 29.1 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat YfmQ PF10787.4 CBK21057.2 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group EFG_II PF14492.1 CBK21057.2 - 0.15 11.9 0.1 8.7 6.2 0.0 2.6 2 1 0 2 2 2 0 Elongation Factor G, domain II Pkinase PF00069.20 CBK21058.2 - 4.9e-32 111.0 0.0 5.9e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21058.2 - 1.5e-30 106.1 0.0 1.8e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBK21058.2 - 0.018 14.6 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RNA_pol_Rpb6 PF01192.17 CBK21059.2 - 3.8e-22 77.7 0.2 4.6e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 CBK21060.2 - 4e-10 39.4 14.9 0.00093 19.3 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type HMG_box PF00505.14 CBK21060.2 - 1.1e-07 31.9 0.4 1.1e-07 31.9 0.2 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box zf-C2H2_4 PF13894.1 CBK21060.2 - 5.5e-06 26.3 10.5 0.13 12.6 0.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK21060.2 - 7e-06 26.0 19.1 2.5e-05 24.3 0.1 4.6 5 0 0 5 5 4 2 Zinc-finger double domain HMG_box_2 PF09011.5 CBK21060.2 - 9.4e-06 25.9 0.3 9.4e-06 25.9 0.2 2.8 2 1 1 3 3 3 1 HMG-box domain GAS PF13851.1 CBK21060.2 - 0.0019 17.4 6.3 0.0031 16.7 4.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 CBK21060.2 - 0.016 13.6 1.4 0.021 13.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4071 PF13281.1 CBK21060.2 - 0.019 13.8 0.4 0.028 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) zf-C2H2_jaz PF12171.3 CBK21060.2 - 0.02 15.0 4.4 0.22 11.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding bZIP_1 PF00170.16 CBK21060.2 - 0.048 13.6 8.1 0.1 12.5 5.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-H2C2_5 PF13909.1 CBK21060.2 - 0.058 13.6 0.1 0.058 13.6 0.1 3.9 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CBK21060.2 - 0.083 12.8 3.8 0.083 12.8 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3133 PF11331.3 CBK21060.2 - 0.13 11.8 1.7 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Ogr_Delta PF04606.7 CBK21060.2 - 0.14 11.8 1.9 0.23 11.1 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger CpXC PF14353.1 CBK21060.2 - 0.19 11.7 5.6 1 9.3 0.0 2.8 1 1 1 2 2 2 0 CpXC protein IncA PF04156.9 CBK21060.2 - 0.24 10.9 3.5 0.37 10.3 2.4 1.3 1 0 0 1 1 1 0 IncA protein Cauli_AT PF03233.8 CBK21060.2 - 0.48 10.1 5.9 1.1 8.9 2.6 2.1 2 0 0 2 2 2 0 Aphid transmission protein zf-AN1 PF01428.11 CBK21060.2 - 4.3 7.2 7.4 0.9 9.4 0.4 2.9 3 0 0 3 3 3 0 AN1-like Zinc finger HSP70 PF00012.15 CBK21061.2 - 1e-127 426.6 0.1 1.5e-127 426.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21061.2 - 2.7e-17 62.3 0.4 1.5e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Methyltransf_31 PF13847.1 CBK21063.2 - 2.9e-05 23.7 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK21063.2 - 0.00033 21.0 0.0 0.00037 20.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK21063.2 - 0.004 17.7 0.0 0.0046 17.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK21063.2 - 0.015 15.7 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Hexokinase_2 PF03727.11 CBK21063.2 - 0.13 11.4 0.2 0.15 11.2 0.1 1.0 1 0 0 1 1 1 0 Hexokinase Ribosomal_S6e PF01092.14 CBK21064.2 - 9.7e-59 196.5 0.3 1.7e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Galactosyl_T PF01762.16 CBK21065.2 - 5.8e-30 104.3 0.1 2.8e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 Galactosyltransferase Dus PF01207.12 CBK21066.2 - 7.6e-55 185.9 0.0 8.4e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CBK21066.2 - 8.6e-08 31.7 0.0 2.1e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 CBK21066.2 - 0.00034 19.7 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 CBK21066.2 - 0.00067 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 CBK21066.2 - 0.0023 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) NanE PF04131.9 CBK21066.2 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.20 CBK21066.2 - 0.02 13.8 0.1 0.039 12.8 0.0 1.4 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CBK21066.2 - 0.026 13.3 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IGPS PF00218.16 CBK21066.2 - 0.052 12.5 0.0 0.1 11.5 0.0 1.3 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Oxidored_FMN PF00724.15 CBK21066.2 - 0.055 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family NMO PF03060.10 CBK21066.2 - 0.14 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribosomal_S3Ae PF01015.13 CBK21067.2 - 2.6e-74 248.7 4.1 3.4e-74 248.4 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.17 CBK21067.2 - 0.00096 18.9 0.3 0.0029 17.3 0.1 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.11 CBK21067.2 - 0.048 13.0 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Chitin_bind_1 PF00187.14 CBK21067.2 - 0.23 11.4 4.0 0.49 10.4 2.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein NIF PF03031.13 CBK21068.2 - 3e-18 65.9 0.3 3.7e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ENTH PF01417.15 CBK21070.2 - 2.4e-31 108.1 0.1 4.2e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CBK21070.2 - 0.0045 15.7 0.0 0.0092 14.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain Nop14 PF04147.7 CBK21070.2 - 0.58 8.0 27.5 0.74 7.6 19.0 1.3 1 0 0 1 1 1 0 Nop14-like family AMP-binding PF00501.23 CBK21071.2 - 1.8e-79 267.0 0.0 2.3e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RhoGEF PF00621.15 CBK21072.2 - 3.1e-48 164.0 0.4 3.9e-48 163.7 0.3 1.1 1 0 0 1 1 1 1 RhoGEF domain Sec63 PF02889.11 CBK21073.2 - 8.6e-160 531.0 0.0 3.2e-94 315.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBK21073.2 - 8.1e-45 152.3 0.4 9.8e-26 90.2 0.1 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 CBK21073.2 - 4.2e-14 52.8 0.0 6.9e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBK21073.2 - 2.5e-09 36.8 0.0 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBK21073.2 - 1.3e-06 27.4 0.1 3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CBK21073.2 - 0.01 15.9 0.1 0.1 12.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0158 PF03682.8 CBK21073.2 - 0.018 14.6 0.7 0.053 13.1 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) AAA_19 PF13245.1 CBK21073.2 - 0.022 14.4 0.8 0.15 11.8 0.0 3.0 4 0 0 4 4 4 0 Part of AAA domain E1-E2_ATPase PF00122.15 CBK21074.2 - 5.5e-66 221.8 0.6 1.7e-65 220.2 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK21074.2 - 6.5e-49 165.9 0.6 6.5e-49 165.9 0.4 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK21074.2 - 1e-28 101.2 0.2 1.3e-27 97.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK21074.2 - 2.7e-23 81.7 0.0 4.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBK21074.2 - 2e-20 71.9 0.9 6e-20 70.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBK21074.2 - 1.3e-12 48.2 0.0 4.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK21074.2 - 3.3e-05 23.5 0.6 0.0003 20.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RrnaAD PF00398.15 CBK21075.2 - 1.4e-56 191.4 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CBK21075.2 - 9e-09 35.3 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK21075.2 - 8.5e-07 28.4 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBK21075.2 - 1e-06 29.2 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK21075.2 - 2.6e-06 27.1 0.0 5.4e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CBK21075.2 - 2e-05 24.2 0.1 3.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 CBK21075.2 - 0.00014 21.4 0.3 0.0067 16.0 0.1 2.1 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.13 CBK21075.2 - 0.00035 20.2 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 CBK21075.2 - 0.00042 20.7 0.0 0.00082 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBK21075.2 - 0.00045 19.6 0.0 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 CBK21075.2 - 0.00082 18.9 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PRMT5 PF05185.11 CBK21075.2 - 0.0021 17.0 0.1 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 CBK21075.2 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK21075.2 - 0.0033 17.8 0.0 0.0098 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK21075.2 - 0.0042 17.4 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBK21075.2 - 0.0069 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 CBK21075.2 - 0.0071 15.4 0.1 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 CBK21075.2 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.6 CBK21075.2 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Acetyltransf_4 PF13420.1 CBK21076.2 - 0.067 13.1 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK21076.2 - 0.09 12.8 0.1 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HSP70 PF00012.15 CBK21077.2 - 1.2e-73 247.9 0.0 1.6e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.6 CBK21077.2 - 0.00043 19.3 0.2 0.026 13.4 0.1 2.3 1 1 1 2 2 2 2 StbA protein FtsA PF14450.1 CBK21077.2 - 0.19 11.5 0.9 21 4.9 0.0 3.4 2 1 0 2 2 2 0 Cell division protein FtsA HAT PF02184.11 CBK21078.2 - 1.1e-10 41.0 7.9 5.8e-07 29.1 0.5 3.5 3 0 0 3 3 3 3 HAT (Half-A-TPR) repeat U3_assoc_6 PF08640.6 CBK21078.2 - 0.00021 21.0 4.7 0.0034 17.1 1.3 2.3 1 1 1 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 CBK21078.2 - 0.0012 18.6 0.0 1.5 8.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21078.2 - 0.0026 18.2 0.2 0.79 10.5 0.0 3.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21078.2 - 0.005 17.4 0.0 0.012 16.2 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21078.2 - 0.015 15.6 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.9 CBK21078.2 - 0.018 14.7 0.3 0.018 14.7 0.2 1.5 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) TPR_12 PF13424.1 CBK21078.2 - 0.11 12.4 0.1 5.9 6.9 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.15 CBK21079.2 - 3.6e-84 282.8 0.0 4.4e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21079.2 - 1.4e-15 56.7 0.3 1.4e-13 50.1 0.1 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBK21079.2 - 0.2 11.4 4.4 8.8 6.1 0.5 3.5 3 1 0 3 3 3 0 Cell division protein FtsA HSP70 PF00012.15 CBK21080.2 - 1.3e-64 218.1 0.1 1.7e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21080.2 - 1e-14 53.9 0.0 3.7e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.6 CBK21080.2 - 0.00064 18.7 0.7 0.026 13.4 0.5 2.3 1 1 0 1 1 1 1 StbA protein Pyrophosphatase PF00719.14 CBK21081.2 - 1.1e-37 128.9 0.1 1.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lung_7-TM_R PF06814.8 CBK21082.2 - 1.6e-25 89.6 7.1 7.4e-25 87.4 5.1 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBK21082.2 - 9.1e-05 21.7 7.2 9.1e-05 21.7 5.0 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain zf-RING_2 PF13639.1 CBK21083.2 - 1.8e-14 53.2 8.1 1.8e-14 53.2 5.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_3 PF14369.1 CBK21083.2 - 2.6e-09 36.9 15.8 8.6e-08 32.0 2.6 3.4 3 0 0 3 3 3 2 zinc-finger zf-rbx1 PF12678.2 CBK21083.2 - 1.9e-08 34.3 5.5 1.9e-08 34.3 3.8 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBK21083.2 - 4.4e-08 33.0 8.4 4.4e-08 33.0 5.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK21083.2 - 1.2e-06 28.0 9.3 1.2e-06 28.0 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK21083.2 - 2.6e-06 26.9 7.1 2.6e-06 26.9 4.9 3.1 2 2 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK21083.2 - 2.8e-06 26.9 5.8 2.8e-06 26.9 4.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBK21083.2 - 4e-05 23.3 2.0 4e-05 23.3 1.4 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 CBK21083.2 - 0.0017 18.1 10.8 0.41 10.5 1.0 3.3 3 0 0 3 3 3 2 Double zinc ribbon TerY-C PF15616.1 CBK21083.2 - 0.0031 17.4 1.0 0.0031 17.4 0.7 2.1 2 0 0 2 2 2 1 TerY-C metal binding domain Rad50_zn_hook PF04423.9 CBK21083.2 - 0.007 15.8 1.7 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif PHD PF00628.24 CBK21083.2 - 0.049 13.3 19.8 0.086 12.5 3.8 3.2 2 1 1 3 3 3 0 PHD-finger HypA PF01155.14 CBK21083.2 - 0.059 13.0 7.9 0.079 12.6 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 CBK21083.2 - 0.097 12.4 11.7 0.37 10.6 3.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Vps39_2 PF10367.4 CBK21083.2 - 0.1 12.7 0.4 0.1 12.7 0.3 3.4 4 0 0 4 4 3 0 Vacuolar sorting protein 39 domain 2 zf-RING_6 PF14835.1 CBK21083.2 - 0.24 11.1 3.3 0.39 10.5 1.1 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein YdjO PF14169.1 CBK21083.2 - 0.26 10.7 0.1 0.26 10.7 0.0 3.0 3 1 0 3 3 3 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.1 CBK21083.2 - 0.33 10.8 17.0 0.65 9.9 4.7 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sgf11 PF08209.6 CBK21083.2 - 0.59 9.4 0.1 0.59 9.4 0.1 3.2 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-CHY PF05495.7 CBK21083.2 - 0.61 10.2 11.7 0.3 11.2 1.8 2.8 2 1 0 2 2 2 0 CHY zinc finger Prok-RING_1 PF14446.1 CBK21083.2 - 0.77 9.5 14.4 0.84 9.4 3.4 3.5 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 CBK21083.2 - 0.87 9.3 9.7 0.12 12.1 3.4 2.1 2 1 0 2 2 1 0 RING-type zinc-finger zinc_ribbon_2 PF13240.1 CBK21083.2 - 1.6 8.3 11.1 6.8 6.3 1.8 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 CBK21083.2 - 2.7 7.8 16.7 6.9 6.5 2.6 3.2 2 2 1 3 3 3 0 zinc-ribbons FANCL_C PF11793.3 CBK21083.2 - 3 7.8 9.4 13 5.8 4.5 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 CBK21083.2 - 3.1 7.4 12.1 6.3 6.4 3.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 LIM PF00412.17 CBK21083.2 - 5.7 7.0 13.2 6.1 7.0 1.2 3.4 2 2 0 2 2 2 0 LIM domain zf-RING_4 PF14570.1 CBK21083.2 - 7.7 6.1 15.8 0.067 12.7 3.5 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L18e PF00828.14 CBK21084.2 - 6e-09 36.3 0.0 8.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Slx4 PF09494.5 CBK21084.2 - 0.0033 17.1 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease MORN PF02493.15 CBK21084.2 - 0.11 12.2 0.2 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 MORN repeat Porin_3 PF01459.17 CBK21087.2 - 0.032 13.5 0.0 0.033 13.4 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic porin PT PF04886.7 CBK21088.2 - 0.00018 20.7 7.7 0.00018 20.7 5.3 8.1 5 2 3 8 8 8 3 PT repeat NDUFB10 PF10249.4 CBK21089.2 - 5.2e-06 26.6 0.1 6.1e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 COX17 PF05051.8 CBK21089.2 - 0.0077 16.2 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) GDA1_CD39 PF01150.12 CBK21090.2 - 1.9e-07 29.9 0.0 2.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.12 CBK21091.2 - 3e-39 134.7 0.0 7.7e-39 133.3 0.0 1.5 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family OxoDH_E1alpha_N PF12573.3 CBK21091.2 - 0.055 13.0 0.4 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal EMG1 PF03587.9 CBK21092.2 - 3.5e-53 179.9 0.0 3.9e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TBCC PF07986.7 CBK21092.2 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C PHF5 PF03660.9 CBK21093.2 - 2e-43 146.8 13.9 2.3e-43 146.6 9.6 1.0 1 0 0 1 1 1 1 PHF5-like protein C1_2 PF03107.11 CBK21093.2 - 0.021 14.9 2.2 0.021 14.9 1.5 2.9 2 1 0 2 2 2 0 C1 domain DZR PF12773.2 CBK21093.2 - 0.083 12.7 1.7 0.083 12.7 1.2 3.0 2 1 0 2 2 2 0 Double zinc ribbon PolC_DP2 PF03833.8 CBK21093.2 - 0.26 8.8 5.5 0.3 8.7 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Adaptin_N PF01602.15 CBK21094.2 - 4.2e-128 427.9 8.9 5.2e-128 427.6 6.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK21094.2 - 4.2e-20 72.3 0.2 4.2e-20 72.3 0.2 3.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK21094.2 - 1.8e-08 34.5 5.9 1.4e-05 25.3 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CBK21094.2 - 2.6e-08 33.2 7.8 0.0052 16.7 0.1 5.7 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.3 CBK21094.2 - 4.2e-05 23.0 0.2 0.0005 19.4 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.1 CBK21094.2 - 0.00046 20.5 4.1 0.17 12.4 0.3 4.6 4 0 0 4 4 4 1 HEAT-like repeat SMC_N PF02463.14 CBK21095.2 - 1.4e-59 201.0 0.0 1.2e-58 197.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK21095.2 - 6.6e-22 77.7 0.7 6e-21 74.6 0.1 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK21095.2 - 6.2e-11 42.7 0.7 5.7e-07 29.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CBK21095.2 - 0.044 13.3 0.0 0.45 10.0 0.0 2.3 1 1 0 1 1 1 0 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CBK21095.2 - 0.054 12.6 16.4 0.77 8.8 0.9 4.6 2 2 2 4 4 4 0 Reovirus sigma C capsid protein tRNA-synt_2b PF00587.20 CBK21096.2 - 5.8e-44 149.7 0.0 1.1e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK21096.2 - 1.2e-20 73.2 0.2 2.2e-20 72.3 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CBK21096.2 - 1.6e-10 40.7 0.0 9.2e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CBK21096.2 - 9.1e-09 35.0 0.0 1.8e-06 27.7 0.0 3.0 2 1 0 2 2 2 1 TGS domain He_PIG PF05345.7 CBK21097.2 - 1.3e-08 34.6 15.0 2.9e-06 27.1 1.3 3.3 3 0 0 3 3 3 2 Putative Ig domain OSTbeta PF15048.1 CBK21097.2 - 0.021 14.9 0.2 0.057 13.5 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Rifin_STEVOR PF02009.11 CBK21097.2 - 0.21 11.2 0.9 0.37 10.3 0.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family P12 PF12669.2 CBK21097.2 - 5 7.3 6.4 9.6 6.4 4.5 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family RELT PF12606.3 CBK21097.2 - 5.9 6.1 9.1 14 4.9 6.3 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 RNA_pol_Rpb2_6 PF00562.23 CBK21098.2 - 5.7e-110 367.6 0.0 7.7e-110 367.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBK21098.2 - 1.7e-30 105.4 0.0 2.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBK21098.2 - 1.4e-23 82.4 0.0 2.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CBK21098.2 - 8.5e-23 80.7 0.1 1.3e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CBK21098.2 - 2.6e-20 72.4 0.0 7.4e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 CBK21098.2 - 1.5e-11 44.0 0.0 4.1e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_5 PF04567.12 CBK21098.2 - 0.0006 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_S11 PF00411.14 CBK21099.2 - 2.5e-41 140.2 0.3 3.2e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 CBK21099.2 - 0.03 13.2 0.1 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 CBK21099.2 - 0.074 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Condensin2nSMC PF12422.3 CBK21100.2 - 5.1e-14 52.2 0.3 1.4e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 CBK21100.2 - 1.3e-07 31.0 2.8 0.3 11.2 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CBK21100.2 - 3.4e-05 23.7 1.7 0.00062 19.6 0.2 2.7 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK21100.2 - 0.0048 17.1 0.1 3.6 7.9 0.1 3.0 2 1 1 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 CBK21100.2 - 0.0059 14.9 0.4 0.065 11.5 0.0 2.1 1 1 1 2 2 2 1 Adaptin N terminal region Toxin_4 PF00706.12 CBK21100.2 - 0.044 14.0 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin RNA_pol_A_bac PF01000.21 CBK21101.2 - 3.2e-25 88.4 0.5 1.5e-24 86.3 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBK21101.2 - 5.7e-16 57.4 0.0 8e-16 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 CBK21101.2 - 0.066 12.6 0.0 14 5.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CCCH PF00642.19 CBK21103.2 - 0.0025 17.4 5.1 0.0044 16.6 3.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAT1 PF09770.4 CBK21103.2 - 0.099 10.8 15.2 0.13 10.4 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCCH_2 PF14608.1 CBK21103.2 - 0.49 10.4 6.0 1.2 9.2 4.2 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Neisseria_TspB PF05616.8 CBK21103.2 - 0.65 8.2 3.2 1.3 7.3 2.4 1.4 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein NOA36 PF06524.7 CBK21103.2 - 1.6 7.9 4.9 3.2 6.9 3.4 1.4 1 0 0 1 1 1 0 NOA36 protein PHD PF00628.24 CBK21104.2 - 8.9e-09 34.9 0.6 1.2e-08 34.4 0.4 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBK21104.2 - 0.0027 17.7 0.1 0.0033 17.5 0.1 1.1 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CBK21104.2 - 0.007 15.6 2.1 0.01 15.1 0.2 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CBK21104.2 - 0.0088 15.7 1.0 0.013 15.2 0.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 CBK21104.2 - 0.015 15.0 3.2 0.027 14.1 2.2 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 CBK21104.2 - 0.015 15.2 0.1 0.025 14.5 0.1 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_jaz PF12171.3 CBK21104.2 - 0.044 13.9 2.1 4.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-PHD-like PF15446.1 CBK21104.2 - 0.1 11.8 0.4 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_3 PF07649.7 CBK21104.2 - 0.15 12.1 5.4 0.27 11.3 3.7 1.4 1 1 0 1 1 1 0 C1-like domain zf-H2C2_2 PF13465.1 CBK21104.2 - 0.32 11.3 3.5 8.6 6.8 2.4 2.3 1 1 0 1 1 1 0 Zinc-finger double domain C1_2 PF03107.11 CBK21104.2 - 2.1 8.5 5.3 15 5.8 3.7 2.0 1 1 0 1 1 1 0 C1 domain WD40 PF00400.27 CBK21105.2 - 4.4e-60 197.5 18.6 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK21105.2 - 6.1e-05 21.3 9.4 0.0065 14.6 0.1 4.3 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK21105.2 - 0.002 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK21105.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK21105.2 - 0.007 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK21105.2 - 0.01 14.7 0.2 0.54 9.1 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.1 CBK21105.2 - 0.058 13.6 0.1 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Gmad1 PF10647.4 CBK21105.2 - 0.073 12.4 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Ribosomal_L23 PF00276.15 CBK21107.2 - 1.5e-09 37.7 0.1 1.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Asp23 PF03780.8 CBK21107.2 - 0.071 13.3 0.1 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Asp23 family SapB_1 PF05184.10 CBK21107.2 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 HALZ PF02183.13 CBK21108.2 - 0.00057 19.5 1.7 0.00057 19.5 1.2 4.8 5 0 0 5 5 5 1 Homeobox associated leucine zipper Not3 PF04065.10 CBK21108.2 - 0.0031 16.8 8.6 0.0031 16.8 6.0 2.9 1 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component TPR_MLP1_2 PF07926.7 CBK21108.2 - 0.014 15.0 13.1 0.014 15.0 9.1 3.7 2 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 CBK21108.2 - 0.016 14.7 21.1 0.56 9.7 1.5 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Kinesin-relat_1 PF12711.2 CBK21108.2 - 0.028 14.8 1.0 0.028 14.8 0.7 3.5 3 1 1 4 4 4 0 Kinesin motor Fib_alpha PF08702.5 CBK21108.2 - 0.14 12.2 11.6 0.071 13.2 5.3 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 CBK21108.2 - 0.2 11.5 3.6 19 5.2 0.0 3.4 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FTO_CTD PF12934.2 CBK21108.2 - 0.22 11.0 4.6 1.5 8.4 0.1 2.5 1 1 1 2 2 2 0 FTO C-terminal domain BRE1 PF08647.6 CBK21108.2 - 0.23 11.4 22.4 0.079 12.9 8.7 3.4 2 1 2 4 4 3 0 BRE1 E3 ubiquitin ligase Phage_GP20 PF06810.6 CBK21108.2 - 0.29 10.5 15.8 5.6 6.3 2.9 4.1 2 1 0 3 3 3 0 Phage minor structural protein GP20 Macoilin PF09726.4 CBK21108.2 - 0.46 8.7 23.9 0.79 7.9 16.5 1.4 1 1 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CBK21108.2 - 0.5 9.9 30.6 0.26 10.8 3.7 3.1 1 1 1 2 2 2 0 IncA protein FUSC PF04632.7 CBK21108.2 - 0.55 8.5 3.4 0.61 8.4 2.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF812 PF05667.6 CBK21108.2 - 0.62 8.5 24.3 0.17 10.3 13.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.1 CBK21108.2 - 0.65 8.8 6.8 0.14 11.1 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIVA PF05103.8 CBK21108.2 - 0.65 10.0 20.4 0.14 12.1 8.6 3.1 2 2 1 3 3 3 0 DivIVA protein Tweety PF04906.8 CBK21108.2 - 0.76 8.1 4.6 11 4.2 1.6 2.2 2 0 0 2 2 2 0 Tweety DUF3573 PF12097.3 CBK21108.2 - 1 7.8 7.3 1.3 7.5 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.10 CBK21108.2 - 1.5 8.3 19.9 1.3 8.5 0.3 5.0 2 2 3 5 5 5 0 Septum formation initiator DUF972 PF06156.8 CBK21108.2 - 1.7 9.0 24.0 10 6.4 6.7 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 CBK21108.2 - 1.9 8.2 13.5 1.3 8.7 4.3 2.7 1 1 1 2 2 2 0 Laminin Domain II DUF883 PF05957.8 CBK21108.2 - 4 7.8 14.2 0.67 10.3 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 CBK21108.2 - 5.9 6.7 8.1 2.2 8.0 3.2 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) DUF2968 PF11180.3 CBK21108.2 - 6 6.2 14.1 1.3 8.3 5.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Prefoldin PF02996.12 CBK21108.2 - 9.3 5.9 18.7 0.68 9.5 1.3 4.4 4 2 0 4 4 4 0 Prefoldin subunit HSP70 PF00012.15 CBK21109.2 - 1e-84 284.5 0.0 1.3e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21109.2 - 3.2e-16 58.8 0.1 5.3e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBK21109.2 - 0.27 11.0 4.5 14 5.5 0.5 3.7 2 2 0 2 2 2 0 Cell division protein FtsA HAT PF02184.11 CBK21110.2 - 2.6e-23 81.4 45.0 4.9e-07 29.3 0.7 12.2 12 1 0 12 12 12 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CBK21110.2 - 2.8e-23 80.3 11.8 0.066 13.8 0.0 11.5 5 4 7 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21110.2 - 3.4e-18 65.7 0.9 5.8e-05 23.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21110.2 - 4.7e-14 52.5 8.3 0.00068 20.2 0.0 7.5 7 2 1 8 8 8 2 Tetratricopeptide repeat Suf PF05843.9 CBK21110.2 - 5.2e-14 52.6 37.8 5.1e-11 42.8 1.7 7.5 2 2 3 5 5 5 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBK21110.2 - 1.4e-08 33.9 12.0 0.32 11.0 0.1 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBK21110.2 - 3.9e-07 29.8 25.8 0.0027 17.4 2.0 7.1 8 0 0 8 8 8 4 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 CBK21110.2 - 9.6e-07 28.5 2.3 0.84 9.9 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK21110.2 - 2.8e-06 26.7 11.1 3 7.8 0.1 7.8 6 2 2 8 8 8 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CBK21110.2 - 4.5e-06 26.3 22.4 0.0094 15.6 0.9 8.1 5 2 3 8 8 8 2 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 CBK21110.2 - 1.6e-05 24.7 14.0 0.049 13.5 0.1 7.3 6 3 3 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK21110.2 - 0.0001 22.4 15.9 16 6.2 0.1 9.3 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBK21110.2 - 0.00016 21.1 15.2 1.4 8.9 0.2 7.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21110.2 - 0.00026 20.4 0.6 4.3 7.0 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK21110.2 - 0.016 14.8 18.4 2 8.1 0.1 6.4 4 2 4 8 8 8 0 TPR repeat AAA_16 PF13191.1 CBK21110.2 - 0.044 13.7 0.7 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ist1 PF03398.9 CBK21111.2 - 4.7e-12 45.6 5.4 8.2e-12 44.8 3.7 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3827 PF12877.2 CBK21111.2 - 7.9 4.4 19.4 10 4.1 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4407 PF14362.1 CBK21111.2 - 9.1 5.1 12.5 4.7 6.0 7.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GWT1 PF06423.7 CBK21112.2 - 7.5e-13 48.7 11.9 2.5e-12 47.0 8.3 2.0 1 1 0 1 1 1 1 GWT1 DUF3989 PF13150.1 CBK21112.2 - 0.12 11.8 0.1 0.12 11.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Prenyltrans PF00432.16 CBK21113.2 - 3.1e-39 132.1 4.6 3.6e-11 42.4 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBK21113.2 - 8.9e-25 87.2 0.5 1.7e-14 54.1 0.0 3.1 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBK21113.2 - 0.00016 21.6 0.1 0.0099 15.8 0.0 3.2 1 1 1 2 2 2 2 Prenyltransferase-like RICTOR_N PF14664.1 CBK21114.2 - 0.054 12.0 0.0 0.096 11.2 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Pkinase PF00069.20 CBK21115.2 - 8.8e-13 47.9 0.0 3.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain GAS PF13851.1 CBK21116.2 - 0.005 16.0 15.0 0.005 16.0 10.4 2.3 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 CBK21116.2 - 0.011 15.7 18.1 0.21 11.6 6.2 3.2 2 1 1 3 3 3 0 DivIVA protein DUF3256 PF11644.3 CBK21116.2 - 0.026 14.0 0.8 0.041 13.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) NDUFB10 PF10249.4 CBK21116.2 - 0.053 13.6 0.8 0.053 13.6 0.6 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 IncA PF04156.9 CBK21116.2 - 0.11 12.1 24.3 0.53 9.8 9.2 2.1 2 0 0 2 2 2 0 IncA protein HALZ PF02183.13 CBK21116.2 - 0.18 11.5 0.1 0.18 11.5 0.0 3.8 3 2 0 3 3 3 0 Homeobox associated leucine zipper DUF2203 PF09969.4 CBK21116.2 - 0.49 10.6 13.1 0.076 13.2 0.6 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.3 CBK21116.2 - 0.58 10.0 25.4 0.11 12.4 1.1 3.1 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CBK21116.2 - 0.69 8.9 23.4 0.85 8.6 2.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 CBK21116.2 - 0.84 9.4 24.4 2.5 7.8 7.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 CBK21116.2 - 0.9 9.9 18.4 1.3 9.3 1.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) CASP_C PF08172.7 CBK21116.2 - 1.2 8.1 18.1 0.25 10.3 0.3 2.8 2 1 1 3 3 3 0 CASP C terminal FAD-SLDH PF12318.3 CBK21116.2 - 1.9 8.1 4.9 1.9 8.1 0.8 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Rotamase PF00639.16 CBK21116.2 - 2.2 9.0 5.4 1.4 9.6 1.0 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF3450 PF11932.3 CBK21116.2 - 2.3 7.4 17.7 0.61 9.3 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) THOC7 PF05615.8 CBK21116.2 - 5.3 7.3 17.9 11 6.3 6.6 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 Tropomyosin PF00261.15 CBK21117.2 - 0.00095 18.3 5.6 0.00095 18.3 3.9 3.3 2 1 1 3 3 3 1 Tropomyosin Filament PF00038.16 CBK21117.2 - 0.0043 16.5 9.8 0.0043 16.5 6.8 3.7 1 1 3 4 4 4 2 Intermediate filament protein ATG16 PF08614.6 CBK21117.2 - 0.01 15.7 58.3 0.029 14.2 13.7 3.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) IncA PF04156.9 CBK21117.2 - 0.02 14.5 69.7 0.23 11.0 13.2 4.1 1 1 2 3 3 3 0 IncA protein AAA_13 PF13166.1 CBK21117.2 - 0.12 10.8 32.5 0.17 10.2 19.1 2.0 2 0 0 2 2 2 0 AAA domain EzrA PF06160.7 CBK21117.2 - 0.16 10.0 41.8 0.53 8.4 17.8 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.9 CBK21117.2 - 0.2 11.2 31.8 0.17 11.5 6.5 3.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain WEMBL PF05701.6 CBK21117.2 - 0.36 9.2 56.3 2.1 6.6 15.1 3.8 1 1 2 3 3 3 0 Weak chloroplast movement under blue light DUF641 PF04859.7 CBK21117.2 - 0.46 10.2 38.9 0.087 12.5 2.0 4.3 3 2 1 4 4 4 0 Plant protein of unknown function (DUF641) ACT_5 PF13710.1 CBK21117.2 - 0.58 10.0 6.3 1 9.2 0.2 3.0 2 1 0 2 2 2 0 ACT domain DUF310 PF03750.8 CBK21117.2 - 0.64 10.2 12.9 0.96 9.6 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF310) Tropomyosin_1 PF12718.2 CBK21117.2 - 0.73 9.6 52.6 0.08 12.7 15.1 3.4 2 1 1 3 3 3 0 Tropomyosin like Atg14 PF10186.4 CBK21117.2 - 0.89 8.4 48.2 2 7.2 3.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 CBK21117.2 - 1.1 8.5 86.6 0.12 11.6 7.0 4.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 CBK21117.2 - 1.1 7.8 44.6 0.35 9.4 2.6 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CBK21117.2 - 1.1 8.9 49.2 0.097 12.4 8.9 4.4 1 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 CBK21117.2 - 1.9 7.6 46.4 0.34 10.0 1.5 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 CBK21117.2 - 2.4 7.9 20.8 3.6 7.3 6.4 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 CBK21117.2 - 2.6 8.1 38.6 0.027 14.4 6.1 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.14 CBK21117.2 - 3.3 5.2 53.5 2.5 5.7 3.1 3.3 1 1 0 2 2 2 0 Myosin tail Laminin_II PF06009.7 CBK21117.2 - 3.3 7.4 41.2 0.085 12.6 6.7 4.2 1 1 3 4 4 4 0 Laminin Domain II DUF4140 PF13600.1 CBK21117.2 - 6.1 7.3 48.1 1.5 9.2 1.6 5.5 2 2 4 6 6 6 0 N-terminal domain of unknown function (DUF4140) Leu_zip PF15294.1 CBK21117.2 - 7.1 5.6 45.7 0.039 13.0 2.6 3.0 1 1 2 3 3 3 0 Leucine zipper CorA PF01544.13 CBK21117.2 - 7.5 5.4 29.1 0.47 9.4 0.1 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Reo_sigmaC PF04582.7 CBK21117.2 - 7.6 5.6 33.7 0.71 8.9 5.3 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 CBK21117.2 - 7.7 6.4 20.9 6.2 6.7 2.3 5.3 2 2 5 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF148 PF02520.12 CBK21117.2 - 9.1 6.1 36.6 0.76 9.5 2.6 4.4 2 1 2 4 4 4 0 Domain of unknown function DUF148 TMF_DNA_bd PF12329.3 CBK21118.2 - 2.1e-07 30.6 51.9 0.0014 18.3 9.3 5.2 3 1 1 5 5 5 4 TATA element modulatory factor 1 DNA binding GAS PF13851.1 CBK21118.2 - 1.2e-06 27.9 46.1 1.7e-05 24.0 9.2 3.8 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 CBK21118.2 - 1.4e-06 28.0 50.1 0.0062 16.2 2.0 5.2 2 1 2 5 5 5 3 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 CBK21118.2 - 0.00017 21.3 31.5 0.00047 19.9 5.1 4.7 2 1 2 5 5 5 3 Protein of unknown function (DUF1664) DUF3584 PF12128.3 CBK21118.2 - 0.00031 18.2 51.7 0.00031 18.2 35.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) ADIP PF11559.3 CBK21118.2 - 0.00083 19.2 61.2 0.03 14.2 8.8 5.1 2 1 3 5 5 5 3 Afadin- and alpha -actinin-Binding phiKZ_IP PF12699.2 CBK21118.2 - 0.00099 18.1 8.3 0.0017 17.3 5.8 1.4 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins Reo_sigmaC PF04582.7 CBK21118.2 - 0.0014 17.8 31.4 0.0031 16.7 6.0 2.8 1 1 3 4 4 4 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBK21118.2 - 0.002 16.6 37.7 0.027 12.9 17.7 2.3 1 1 1 2 2 2 2 AAA domain Filament PF00038.16 CBK21118.2 - 0.0038 16.7 49.9 0.089 12.2 18.5 3.9 1 1 1 3 3 3 2 Intermediate filament protein IncA PF04156.9 CBK21118.2 - 0.0042 16.7 73.5 0.32 10.5 15.2 4.9 1 1 4 5 5 5 3 IncA protein BLOC1_2 PF10046.4 CBK21118.2 - 0.0056 16.7 1.2 0.0056 16.7 0.8 5.3 2 1 3 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 CBK21118.2 - 0.007 15.8 2.0 0.007 15.8 1.4 7.4 2 1 5 7 7 7 2 Septum formation initiator Myosin_tail_1 PF01576.14 CBK21118.2 - 0.01 13.6 50.0 0.0083 13.9 29.1 3.1 2 1 1 3 3 3 0 Myosin tail FliJ PF02050.11 CBK21118.2 - 0.014 15.3 21.5 0.014 15.3 14.9 4.5 2 2 2 4 4 3 0 Flagellar FliJ protein Tropomyosin_1 PF12718.2 CBK21118.2 - 0.015 15.1 51.6 0.13 12.0 12.0 4.4 2 1 1 4 4 4 0 Tropomyosin like ATG16 PF08614.6 CBK21118.2 - 0.016 15.0 10.4 0.016 15.0 7.2 4.3 1 1 3 4 4 3 0 Autophagy protein 16 (ATG16) ERM PF00769.14 CBK21118.2 - 0.022 14.2 52.6 0.053 13.0 7.9 4.0 1 1 3 4 4 4 0 Ezrin/radixin/moesin family Spc7 PF08317.6 CBK21118.2 - 0.023 13.3 47.5 0.24 10.0 13.7 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4062 PF13271.1 CBK21118.2 - 0.044 13.8 0.5 9.1 6.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) bZIP_2 PF07716.10 CBK21118.2 - 0.057 13.2 0.1 0.057 13.2 0.1 8.4 8 1 0 8 8 8 0 Basic region leucine zipper DUF342 PF03961.8 CBK21118.2 - 0.062 11.7 27.3 0.19 10.1 5.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBK21118.2 - 0.084 13.2 40.6 1.1 9.5 2.7 5.6 2 1 4 6 6 6 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 CBK21118.2 - 0.12 11.4 42.2 0.016 14.3 12.8 2.3 1 1 1 2 2 2 0 TMCO5 family COG2 PF06148.6 CBK21118.2 - 0.25 11.2 36.8 0.14 12.0 1.8 5.7 4 2 1 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.4 CBK21118.2 - 0.31 11.0 41.3 0.15 12.0 4.7 3.8 2 1 2 4 4 3 0 JNK_SAPK-associated protein-1 APG6 PF04111.7 CBK21118.2 - 0.53 9.2 53.7 0.4 9.6 12.4 3.7 1 1 3 4 4 4 0 Autophagy protein Apg6 Osmo_CC PF08946.5 CBK21118.2 - 0.57 10.2 19.5 3.9 7.5 1.2 5.0 3 1 1 4 4 4 0 Osmosensory transporter coiled coil Tropomyosin PF00261.15 CBK21118.2 - 1 8.3 43.0 2.9 6.9 6.1 4.0 1 1 1 2 2 2 0 Tropomyosin EzrA PF06160.7 CBK21118.2 - 1 7.4 38.4 0.47 8.5 9.8 2.8 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.7 CBK21118.2 - 1.1 9.0 57.7 0.02 14.6 15.5 4.5 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.1 CBK21118.2 - 1.3 8.4 50.6 0.16 11.3 19.5 3.5 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.8 CBK21118.2 - 1.9 6.4 47.1 0.1 10.6 10.2 2.9 1 1 2 3 3 3 0 Mitotic checkpoint protein Ax_dynein_light PF10211.4 CBK21118.2 - 2.1 8.1 43.7 0.029 14.1 7.9 4.6 3 2 2 6 6 6 0 Axonemal dynein light chain DUF2353 PF09789.4 CBK21118.2 - 4.2 6.5 38.7 0.16 11.1 5.2 3.3 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.1 CBK21118.2 - 4.6 7.1 50.8 0.64 9.9 4.2 4.9 1 1 4 5 5 5 0 Ciliary rootlet component, centrosome cohesion DUF479 PF04336.7 CBK21118.2 - 4.9 7.3 20.8 1 9.5 1.5 4.4 2 2 1 4 4 4 0 Protein of unknown function, DUF479 RTBV_P46 PF06216.6 CBK21118.2 - 5.1 5.8 14.1 0.35 9.6 0.8 2.8 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein Atg14 PF10186.4 CBK21118.2 - 6.3 5.6 53.2 4.4 6.1 16.9 3.9 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 CBK21118.2 - 7.3 6.0 44.7 12 5.2 4.2 4.6 1 1 2 4 4 4 0 Phage minor structural protein GP20 DUF2730 PF10805.3 CBK21118.2 - 9.9 5.9 18.5 1.4 8.7 1.4 4.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Ribosomal_L22e PF01776.12 CBK21119.2 - 8.2e-42 141.7 2.3 9.7e-42 141.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2407 PF10302.4 CBK21119.2 - 0.088 13.0 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Apyrase PF06079.6 CBK21121.2 - 1.7e-109 365.5 1.9 2.1e-109 365.2 1.3 1.1 1 0 0 1 1 1 1 Apyrase adh_short PF00106.20 CBK21122.2 - 9.1e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TMCO5 PF14992.1 CBK21123.2 - 0.0013 17.9 18.4 0.0016 17.5 12.8 1.1 1 0 0 1 1 1 1 TMCO5 family CENP-F_leu_zip PF10473.4 CBK21123.2 - 0.012 15.4 20.6 0.05 13.4 1.8 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 CBK21123.2 - 0.018 13.5 16.8 0.051 12.0 8.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HIM1 PF08732.5 CBK21123.2 - 0.052 12.0 2.7 0.056 11.9 1.8 1.1 1 0 0 1 1 1 0 HIM1 Reo_sigmaC PF04582.7 CBK21123.2 - 0.053 12.7 2.8 0.094 11.8 1.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Prefoldin PF02996.12 CBK21123.2 - 0.059 13.0 12.1 0.95 9.1 0.1 3.6 2 1 1 4 4 4 0 Prefoldin subunit Baculo_PEP_C PF04513.7 CBK21123.2 - 0.06 13.1 10.1 0.032 14.0 4.6 2.2 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.1 CBK21123.2 - 0.064 10.9 10.5 0.12 10.0 7.3 1.4 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CBK21123.2 - 0.065 12.9 15.8 1.8 8.1 4.0 2.2 1 1 1 2 2 2 0 Mnd1 family NusB PF01029.13 CBK21123.2 - 0.076 13.0 7.4 0.44 10.5 0.6 2.3 1 1 1 2 2 2 0 NusB family UPF0515 PF15135.1 CBK21123.2 - 0.079 12.0 1.0 0.12 11.4 0.6 1.2 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 IncA PF04156.9 CBK21123.2 - 0.099 12.2 21.5 0.021 14.4 2.6 3.1 1 1 2 3 3 3 0 IncA protein Sigma70_r4_2 PF08281.7 CBK21123.2 - 0.1 12.0 1.9 1.8 8.0 0.3 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 LOH1CR12 PF10158.4 CBK21123.2 - 0.11 12.2 6.4 3 7.6 0.6 2.9 1 1 0 2 2 2 0 Tumour suppressor protein Nnf1 PF03980.9 CBK21123.2 - 0.14 12.1 0.1 0.14 12.1 0.1 3.2 2 1 0 2 2 2 0 Nnf1 Seryl_tRNA_N PF02403.17 CBK21123.2 - 0.2 11.6 18.4 0.92 9.5 2.5 3.3 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CBK21123.2 - 0.32 11.1 14.6 0.088 12.9 4.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 CBK21123.2 - 0.65 9.6 9.4 0.083 12.5 1.3 2.7 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 CDC37_N PF03234.9 CBK21123.2 - 1.3 9.2 15.1 81 3.4 10.5 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF2681 PF10883.3 CBK21123.2 - 1.5 9.1 12.1 3.1 8.0 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) DUF2203 PF09969.4 CBK21123.2 - 1.8 8.8 6.9 1.5 9.0 3.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DivIVA PF05103.8 CBK21123.2 - 2 8.4 13.4 6.3 6.8 0.1 3.3 2 1 1 3 3 3 0 DivIVA protein Prominin PF05478.6 CBK21123.2 - 2.3 5.6 10.4 4.1 4.8 5.5 2.3 1 1 1 2 2 2 0 Prominin AAA_13 PF13166.1 CBK21123.2 - 2.5 6.4 16.2 0.36 9.2 7.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2316 PF10078.4 CBK21123.2 - 3.5 7.6 6.0 8.8 6.4 1.9 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF1664 PF07889.7 CBK21123.2 - 4.2 7.1 14.8 1.7 8.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CBK21123.2 - 4.7 6.9 13.3 1.3 8.8 3.0 2.8 1 1 2 3 3 3 0 Laminin Domain II Med4 PF10018.4 CBK21123.2 - 7.3 5.9 15.7 0.48 9.7 1.4 3.1 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 CBK21123.2 - 7.5 7.0 11.7 5.4 7.4 0.1 3.4 2 1 0 3 3 3 0 SlyX DUF4559 PF15112.1 CBK21123.2 - 7.9 5.5 11.8 12 4.9 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) APG6 PF04111.7 CBK21123.2 - 8.7 5.2 17.8 8 5.4 8.7 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-S PF15630.1 CBK21124.2 - 2.6e-19 69.1 0.0 4.7e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 CBK21124.2 - 3e-06 27.2 0.1 5.3e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 CBK21124.2 - 5.5e-06 25.8 0.1 8.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBK21124.2 - 0.00096 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 CBK21124.2 - 0.0026 17.5 0.4 0.0044 16.8 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Kinetochor_Ybp2 PF08568.5 CBK21124.2 - 0.039 12.2 0.3 0.048 11.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin TFIID_90kDa PF04494.10 CBK21124.2 - 0.045 13.8 0.3 0.074 13.1 0.2 1.3 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit TFIID-31kDa PF02291.10 CBK21124.2 - 0.045 13.5 0.1 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 CBK21124.2 - 0.049 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBK21124.2 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) SNF2_N PF00176.18 CBK21125.2 - 3.9e-10 39.0 0.0 6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 CBK21126.2 - 8.5e-26 90.4 0.4 1.5e-25 89.6 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain MIP-T3 PF10243.4 CBK21127.2 - 2.8e-05 22.8 47.0 4e-05 22.3 32.6 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 CBK21127.2 - 0.00051 18.7 0.0 0.0012 17.5 0.0 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein SprA-related PF12118.3 CBK21127.2 - 0.0021 17.4 19.6 0.0034 16.7 13.6 1.4 1 0 0 1 1 1 1 SprA-related family Daxx PF03344.10 CBK21127.2 - 0.75 8.2 39.5 1 7.7 27.4 1.1 1 0 0 1 1 1 0 Daxx Family U79_P34 PF03064.11 CBK21127.2 - 2.3 7.6 33.1 4.9 6.6 23.0 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cpn60_TCP1 PF00118.19 CBK21128.2 - 2.3e-151 504.7 1.5 2.6e-151 504.5 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2360 PF10152.4 CBK21129.2 - 9.5e-84 279.0 37.2 3.1e-10 40.5 0.2 11.3 11 1 0 11 11 11 9 Predicted coiled-coil domain-containing protein (DUF2360) FH2 PF02181.18 CBK21129.2 - 6.5e-67 225.9 9.6 6.5e-67 225.9 6.7 2.2 1 1 1 2 2 2 1 Formin Homology 2 Domain PHD PF00628.24 CBK21129.2 - 3.5e-06 26.6 8.2 1.3e-05 24.7 5.7 2.1 1 1 0 1 1 1 1 PHD-finger PLAC PF08686.6 CBK21129.2 - 6.1e-05 23.2 22.7 19 5.6 0.1 7.4 7 0 0 7 7 7 0 PLAC (protease and lacunin) domain Thy1 PF02511.10 CBK21129.2 - 0.00059 19.2 6.5 8.5 5.6 0.0 5.9 1 1 3 6 6 6 1 Thymidylate synthase complementing protein Zn_ribbon_recom PF13408.1 CBK21129.2 - 0.0091 16.2 1.4 0.038 14.2 1.0 2.1 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Snapin_Pallidin PF14712.1 CBK21129.2 - 0.15 12.3 5.7 2.4 8.5 1.4 3.6 2 1 1 3 3 3 0 Snapin/Pallidin C1_1 PF00130.17 CBK21129.2 - 0.16 11.6 8.3 0.014 15.1 1.8 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WXG100 PF06013.7 CBK21129.2 - 0.24 11.4 2.5 1.7 8.6 0.2 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG zf-RING_2 PF13639.1 CBK21129.2 - 0.6 9.9 4.9 1.3 8.9 3.4 1.6 1 0 0 1 1 1 0 Ring finger domain OrfB_Zn_ribbon PF07282.6 CBK21129.2 - 0.77 9.4 4.2 0.37 10.4 0.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-PHD-like PF15446.1 CBK21129.2 - 2.4 7.4 9.4 0.21 10.8 2.8 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 CBK21129.2 - 5.9 6.7 10.9 0.31 10.8 3.7 1.7 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 Proteasome PF00227.21 CBK21130.2 - 3.8e-58 195.9 0.1 4.7e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK21130.2 - 2.1e-11 42.9 0.4 2.6e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HSP70 PF00012.15 CBK21132.2 - 0.0004 18.4 0.0 0.0011 17.0 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein TGT_C1 PF14809.1 CBK21132.2 - 0.0061 16.3 0.5 1.6 8.6 0.1 3.0 2 1 1 3 3 3 2 C1 domain of tRNA-guanine transglycosylase dimerisation DUF2828 PF11443.3 CBK21133.2 - 0.22 9.7 0.8 0.3 9.2 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2201_N PF13203.1 CBK21133.2 - 1.7 7.7 4.4 2.5 7.1 3.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain U79_P34 PF03064.11 CBK21133.2 - 7 6.0 17.3 10 5.5 12.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_L6 PF00347.18 CBK21134.2 - 2.4e-29 101.6 4.6 1.2e-14 54.5 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Rsm22 PF09243.5 CBK21135.2 - 4.7e-09 35.6 0.0 8.6e-09 34.8 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CBK21135.2 - 0.0048 17.4 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_5 PF00266.14 CBK21136.2 - 1.3e-32 113.0 0.0 2.1e-32 112.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Myc_N PF01056.13 CBK21137.2 - 0.018 14.2 1.8 0.02 14.0 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region End3 PF12761.2 CBK21137.2 - 0.028 14.0 3.4 0.1 12.2 0.0 2.7 2 1 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Daxx PF03344.10 CBK21137.2 - 0.2 10.1 4.7 0.22 9.9 3.2 1.0 1 0 0 1 1 1 0 Daxx Family Adeno_terminal PF02459.10 CBK21137.2 - 0.2 9.7 2.1 0.24 9.4 1.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein FAM176 PF14851.1 CBK21137.2 - 0.24 11.0 3.0 0.3 10.7 2.1 1.2 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.6 CBK21137.2 - 0.25 11.1 3.0 0.34 10.7 2.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Spt5_N PF11942.3 CBK21137.2 - 0.25 11.9 10.3 0.41 11.3 7.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal BSP_II PF05432.6 CBK21137.2 - 0.27 10.4 5.6 0.31 10.2 3.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 CBK21137.2 - 0.82 10.1 5.6 1.5 9.2 3.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3811 PF11656.3 CBK21138.2 - 0.088 12.8 0.8 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 YjbD family (DUF3811) DUF490 PF04357.8 CBK21138.2 - 0.096 11.7 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF490) Mitofilin PF09731.4 CBK21139.2 - 0.061 11.9 31.4 0.077 11.6 21.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PROCN PF08083.6 CBK21140.2 - 4e-208 690.8 5.9 6.8e-208 690.1 4.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CBK21140.2 - 1.6e-106 354.8 1.6 2.9e-106 354.0 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CBK21140.2 - 1.1e-89 297.8 2.8 2.4e-89 296.7 2.0 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CBK21140.2 - 6e-78 259.7 2.5 2.1e-77 258.0 1.5 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CBK21140.2 - 8.6e-67 222.9 0.1 2.3e-66 221.5 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CBK21140.2 - 1.5e-38 130.5 0.1 4.5e-38 128.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CBK21140.2 - 3.7e-38 130.0 0.0 1e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CBK21140.2 - 3e-07 30.1 0.0 1e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF869 PF05911.6 CBK21141.2 - 0.0012 17.1 53.7 0.0012 17.1 37.2 3.0 1 1 1 3 3 3 1 Plant protein of unknown function (DUF869) Filament PF00038.16 CBK21141.2 - 0.0024 17.4 36.9 0.0024 17.4 25.6 3.5 1 1 1 2 2 2 1 Intermediate filament protein TMF_DNA_bd PF12329.3 CBK21141.2 - 0.0075 16.0 87.9 0.018 14.8 6.2 8.5 8 0 0 8 8 8 5 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 CBK21141.2 - 0.21 11.3 44.4 0.13 12.0 1.5 7.7 7 1 0 7 7 7 0 Homeobox associated leucine zipper Strep_SA_rep PF06696.6 CBK21141.2 - 0.68 9.7 5.8 3.7 7.4 0.2 3.7 3 0 0 3 3 3 0 Streptococcal surface antigen repeat GAS PF13851.1 CBK21141.2 - 2.8 7.0 80.3 2.3 7.3 1.4 5.9 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Peptidase_M41 PF01434.13 CBK21142.2 - 2.1e-63 213.6 0.3 3.2e-63 213.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBK21142.2 - 6.3e-41 139.6 0.0 1.7e-40 138.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBK21142.2 - 4.6e-05 24.2 0.1 0.00019 22.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK21142.2 - 0.00057 19.8 0.1 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CBK21142.2 - 0.00058 19.5 0.3 0.0017 18.0 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBK21142.2 - 0.00067 19.7 0.0 0.024 14.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain FtsH_ext PF06480.10 CBK21142.2 - 0.0011 19.1 2.1 0.0058 16.7 0.0 2.8 3 0 0 3 3 3 1 FtsH Extracellular AAA_5 PF07728.9 CBK21142.2 - 0.0012 18.5 0.0 0.0039 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBK21142.2 - 0.0015 18.4 0.0 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK21142.2 - 0.002 18.1 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CBK21142.2 - 0.0038 16.3 0.0 0.0098 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 CBK21142.2 - 0.005 15.6 0.7 0.0096 14.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 CBK21142.2 - 0.012 14.6 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBK21142.2 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zn_peptidase_2 PF04298.7 CBK21142.2 - 0.03 13.6 0.2 8 5.7 0.0 2.3 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase AAA_25 PF13481.1 CBK21142.2 - 0.03 13.7 1.2 0.65 9.3 0.6 2.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 CBK21142.2 - 0.049 13.9 0.1 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBK21142.2 - 0.084 12.0 0.2 0.24 10.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SF PF00482.18 CBK21143.2 - 0.024 14.5 0.5 0.42 10.5 0.1 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2458 PF10454.4 CBK21143.2 - 0.29 10.9 11.1 0.02 14.7 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Sld5 PF05916.6 CBK21144.2 - 5.3e-06 26.6 1.1 9.8e-06 25.8 0.7 1.6 2 0 0 2 2 2 1 GINS complex protein Ribosomal_S8e PF01201.17 CBK21145.2 - 2.8e-32 111.6 0.1 3.3e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e ACR_tran PF00873.14 CBK21146.2 - 0.069 10.5 0.2 0.1 9.9 0.0 1.2 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family DUF722 PF05263.6 CBK21146.2 - 0.18 11.9 1.8 7.1 6.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF722) Pentapeptide PF00805.17 CBK21148.2 - 0.03 13.5 0.0 0.065 12.4 0.0 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) He_PIG PF05345.7 CBK21151.2 - 8.3e-18 64.1 27.0 4.3e-05 23.4 0.1 5.5 5 0 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK21151.2 - 4.9e-05 23.0 5.1 2.1 8.2 0.0 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.17 CBK21151.2 - 0.0094 15.9 10.4 5.5 7.0 0.0 5.3 5 0 0 5 5 5 1 Hormone receptor domain IncA PF04156.9 CBK21151.2 - 0.01 15.4 0.4 0.016 14.8 0.3 1.2 1 0 0 1 1 1 0 IncA protein PIRT PF15099.1 CBK21151.2 - 0.079 12.1 0.0 0.22 10.7 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family cEGF PF12662.2 CBK21151.2 - 0.15 11.7 4.4 8.4 6.1 0.1 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like DUF4097 PF13349.1 CBK21151.2 - 0.74 9.3 4.4 0.39 10.2 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) hEGF PF12661.2 CBK21151.2 - 1 9.5 7.6 21 5.4 0.1 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF DUF3185 PF11381.3 CBK21151.2 - 5.3 6.8 10.4 15 5.4 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Miro PF08477.8 CBK21152.2 - 9.7e-23 80.9 0.0 4.7e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 CBK21152.2 - 1.1e-16 60.6 0.0 1.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CBK21152.2 - 4e-10 39.6 0.0 2.2e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CBK21152.2 - 1.5e-06 28.3 0.0 0.023 14.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CBK21152.2 - 1.4e-05 24.3 0.0 0.087 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 EF-hand_7 PF13499.1 CBK21152.2 - 2.2e-05 24.4 0.1 0.0024 17.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.1 CBK21152.2 - 2.3e-05 23.8 0.0 0.038 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CBK21152.2 - 5.3e-05 23.0 0.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase MobB PF03205.9 CBK21152.2 - 5.9e-05 22.7 0.0 0.0065 16.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 CBK21152.2 - 7.8e-05 21.9 0.0 0.00027 20.2 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK21152.2 - 7.8e-05 21.9 0.4 0.00022 20.4 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region EF-hand_6 PF13405.1 CBK21152.2 - 0.00014 21.4 1.2 0.0019 17.9 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBK21152.2 - 0.0003 19.8 0.7 0.0003 19.8 0.5 2.6 3 0 0 3 3 3 1 EF hand AAA_16 PF13191.1 CBK21152.2 - 0.00034 20.6 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 CBK21152.2 - 0.00049 19.9 0.5 0.29 10.9 0.1 3.5 3 1 1 4 4 3 1 Dynamin family NACHT PF05729.7 CBK21152.2 - 0.00058 19.5 0.1 0.71 9.5 0.0 3.2 2 1 0 2 2 2 1 NACHT domain SPARC_Ca_bdg PF10591.4 CBK21152.2 - 0.00089 19.2 0.4 1.1 9.2 0.0 3.1 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.22 CBK21152.2 - 0.00093 19.4 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 CBK21152.2 - 0.0011 19.2 0.0 0.68 10.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CBK21152.2 - 0.0019 17.6 0.0 0.11 11.9 0.0 3.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 CBK21152.2 - 0.003 17.0 0.0 0.34 10.3 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 CBK21152.2 - 0.0046 16.9 0.1 0.038 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 CBK21152.2 - 0.0054 15.8 0.0 0.0093 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 CBK21152.2 - 0.01 15.4 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBK21152.2 - 0.011 15.7 0.0 2.4 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK21152.2 - 0.011 15.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 CBK21152.2 - 0.012 15.9 0.0 0.092 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.1 CBK21152.2 - 0.016 14.5 0.5 0.037 13.3 0.4 1.7 1 0 0 1 1 1 0 EF hand EF_assoc_2 PF08356.7 CBK21152.2 - 0.019 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 EF hand associated FeoB_N PF02421.13 CBK21152.2 - 0.02 14.2 0.2 0.52 9.5 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B EF-hand_8 PF13833.1 CBK21152.2 - 0.033 13.8 0.3 0.43 10.2 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair Septin PF00735.13 CBK21152.2 - 0.052 12.5 0.0 0.5 9.3 0.0 2.5 3 0 0 3 3 3 0 Septin DUF815 PF05673.8 CBK21152.2 - 0.073 11.9 0.0 1.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBK21152.2 - 0.097 12.5 0.0 16 5.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_32 PF13654.1 CBK21152.2 - 0.1 11.2 0.0 5.6 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK21152.2 - 0.11 11.9 0.0 0.96 8.8 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CBK21152.2 - 0.12 12.6 0.0 31 4.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_17 PF13207.1 CBK21152.2 - 0.12 13.1 0.0 37 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 CBK21152.2 - 0.14 12.0 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 CBK21152.2 - 0.24 9.9 0.0 4.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.12 CBK21152.2 - 0.34 10.4 1.4 8.3 5.8 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Cpn60_TCP1 PF00118.19 CBK21153.2 - 4.3e-135 451.0 1.1 4.8e-135 450.9 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cript PF10235.4 CBK21154.2 - 6.6e-17 61.6 2.5 6.6e-17 61.6 1.7 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 CBK21154.2 - 0.012 15.4 4.0 0.012 15.4 2.8 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-dskA_traR PF01258.12 CBK21154.2 - 0.021 14.5 5.9 0.61 9.8 0.0 3.3 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger DUF1272 PF06906.6 CBK21154.2 - 0.06 13.2 6.2 0.052 13.3 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-FPG_IleRS PF06827.9 CBK21154.2 - 0.9 9.2 0.1 0.9 9.2 0.0 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Sar8_2 PF03058.9 CBK21154.2 - 1 9.7 12.4 1.1 9.6 5.4 2.4 2 1 0 2 2 2 0 Sar8.2 family zf-HC5HC2H PF13771.1 CBK21154.2 - 1.3 9.2 8.9 1.1 9.4 3.6 2.3 2 1 0 2 2 2 0 PHD-like zinc-binding domain zinc_ribbon_2 PF13240.1 CBK21154.2 - 2.9 7.5 0.0 2.9 7.5 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DUF2039 PF10217.4 CBK21154.2 - 3.3 7.7 15.0 1.6 8.8 5.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) LIM PF00412.17 CBK21154.2 - 4.2 7.5 8.4 2.9 8.0 0.1 3.2 3 1 0 3 3 3 0 LIM domain zf-C3HC4_3 PF13920.1 CBK21154.2 - 8.5 6.1 11.8 28 4.4 0.4 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF3395 PF11875.3 CBK21155.2 - 4.7e-16 58.7 0.0 7.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CBK21155.2 - 4e-09 36.0 1.2 5e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Sec34 PF04136.10 CBK21155.2 - 0.04 13.6 0.4 0.068 12.8 0.3 1.4 1 0 0 1 1 1 0 Sec34-like family Tubulin PF00091.20 CBK21156.2 - 5.8e-70 235.4 0.0 8.4e-70 234.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK21156.2 - 6.9e-47 158.6 0.6 1e-46 158.0 0.4 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBK21156.2 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain P53 PF00870.13 CBK21156.2 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain AAA_16 PF13191.1 CBK21157.2 - 7e-08 32.6 0.0 7.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBK21157.2 - 4.6e-07 30.1 0.0 5.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBK21157.2 - 2.8e-05 23.7 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBK21157.2 - 3.2e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK21157.2 - 0.00024 20.7 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBK21157.2 - 0.001 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 CBK21157.2 - 0.0034 17.1 0.0 0.004 16.8 0.0 1.2 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 CBK21157.2 - 0.0051 15.6 0.0 0.0065 15.3 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 CBK21157.2 - 0.0053 17.5 0.0 0.0086 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK21157.2 - 0.0064 15.2 0.0 0.0069 15.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus ArgK PF03308.11 CBK21157.2 - 0.0093 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 ArgK protein PIF1 PF05970.9 CBK21157.2 - 0.01 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.1 CBK21157.2 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBK21157.2 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBK21157.2 - 0.016 15.3 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 CBK21157.2 - 0.05 12.5 0.0 0.057 12.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_32 PF13654.1 CBK21157.2 - 0.088 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBK21157.2 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CBK21157.2 - 0.1 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBK21157.2 - 0.1 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 CBK21157.2 - 0.12 11.9 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CBK21157.2 - 0.13 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CBK21157.2 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 CBK21157.2 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein GvpD PF07088.6 CBK21157.2 - 0.14 10.4 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein UvrD-helicase PF00580.16 CBK21157.2 - 0.15 11.3 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 CBK21158.2 - 0.00016 21.9 0.3 0.00031 20.9 0.1 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1874 PF08960.5 CBK21158.2 - 0.015 14.9 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1874) GAS PF13851.1 CBK21160.2 - 1.1e-05 24.6 17.9 1.6e-05 24.1 12.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2408 PF10303.4 CBK21160.2 - 8.5e-05 22.6 11.1 0.00015 21.8 7.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Apolipoprotein PF01442.13 CBK21160.2 - 9.8e-05 21.9 10.6 0.00014 21.4 7.3 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.7 CBK21160.2 - 0.00015 21.5 21.9 0.00026 20.7 15.2 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Tup_N PF08581.5 CBK21160.2 - 0.00021 21.3 19.2 0.0006 19.9 2.4 3.2 1 1 2 3 3 3 1 Tup N-terminal Spc7 PF08317.6 CBK21160.2 - 0.0003 19.5 14.7 0.00044 19.0 10.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Lipoprotein_7 PF01540.11 CBK21160.2 - 0.00035 19.7 9.8 0.00049 19.2 6.8 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein ATG16 PF08614.6 CBK21160.2 - 0.00035 20.4 20.2 0.00081 19.2 14.0 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 CBK21160.2 - 0.00045 17.7 11.1 0.00046 17.6 7.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 CBK21160.2 - 0.00073 18.1 11.3 0.00089 17.8 7.8 1.2 1 0 0 1 1 1 1 AAA domain DUF4200 PF13863.1 CBK21160.2 - 0.00093 19.1 10.9 0.00093 19.1 7.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) DUF4455 PF14643.1 CBK21160.2 - 0.0014 17.3 7.6 0.0014 17.3 5.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4455) Filament PF00038.16 CBK21160.2 - 0.0018 17.7 18.8 0.016 14.6 5.0 2.0 1 1 1 2 2 2 2 Intermediate filament protein Seryl_tRNA_N PF02403.17 CBK21160.2 - 0.0019 18.2 17.4 0.0083 16.1 7.3 2.1 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.6 CBK21160.2 - 0.0019 16.6 14.2 0.0022 16.3 9.9 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.14 CBK21160.2 - 0.004 16.7 14.1 0.0054 16.3 9.8 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Cast PF10174.4 CBK21160.2 - 0.0042 15.2 17.6 0.009 14.1 12.2 1.6 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone MbeD_MobD PF04899.7 CBK21160.2 - 0.0049 16.7 5.3 0.11 12.4 1.0 2.3 1 1 1 2 2 2 1 MbeD/MobD like Atg14 PF10186.4 CBK21160.2 - 0.0056 15.6 14.3 0.0081 15.1 9.9 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FlxA PF14282.1 CBK21160.2 - 0.0064 16.4 24.9 0.54 10.2 13.7 2.2 1 1 1 2 2 2 1 FlxA-like protein DUF2046 PF09755.4 CBK21160.2 - 0.0067 15.3 11.2 0.0067 15.3 7.8 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Prominin PF05478.6 CBK21160.2 - 0.0077 13.8 10.1 0.0054 14.3 5.7 1.5 1 1 0 1 1 1 1 Prominin TMF_TATA_bd PF12325.3 CBK21160.2 - 0.011 15.4 14.7 0.011 15.4 10.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Mitofilin PF09731.4 CBK21160.2 - 0.019 13.6 18.0 0.023 13.3 12.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tropomyosin_1 PF12718.2 CBK21160.2 - 0.021 14.6 25.4 0.21 11.4 16.9 2.0 1 1 1 2 2 2 0 Tropomyosin like Josephin PF02099.12 CBK21160.2 - 0.021 14.4 5.0 0.063 12.9 1.4 2.0 1 1 1 2 2 2 0 Josephin Lebercilin PF15619.1 CBK21160.2 - 0.021 14.2 21.5 0.053 12.9 14.9 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spectrin PF00435.16 CBK21160.2 - 0.022 15.0 5.0 0.022 15.0 3.5 2.3 1 1 1 2 2 2 0 Spectrin repeat AKNA PF12443.3 CBK21160.2 - 0.023 14.7 15.3 0.046 13.7 4.1 3.0 1 1 2 3 3 3 0 AT-hook-containing transcription factor FliJ PF02050.11 CBK21160.2 - 0.023 14.7 17.2 0.045 13.7 10.6 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 CBK21160.2 - 0.029 14.1 5.5 0.024 14.4 2.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 CBK21160.2 - 0.03 13.6 15.8 1.2 8.4 7.9 2.1 1 1 1 2 2 2 0 Laminin Domain I WXG100 PF06013.7 CBK21160.2 - 0.031 14.2 2.3 3.7 7.6 0.0 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF342 PF03961.8 CBK21160.2 - 0.032 12.6 12.0 0.041 12.3 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 CBK21160.2 - 0.034 13.9 26.0 0.078 12.7 12.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NAAA-beta PF15508.1 CBK21160.2 - 0.036 14.4 1.3 0.081 13.2 0.4 2.0 1 1 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1640 PF07798.6 CBK21160.2 - 0.044 13.8 17.6 9.9 6.1 12.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3450 PF11932.3 CBK21160.2 - 0.048 12.9 14.0 0.084 12.1 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 CBK21160.2 - 0.049 13.2 25.2 0.32 10.5 2.7 2.3 1 1 1 2 2 2 0 IncA protein zf-C4H2 PF10146.4 CBK21160.2 - 0.06 13.3 16.0 0.078 12.9 11.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein COG5 PF10392.4 CBK21160.2 - 0.063 13.2 14.9 0.07 13.0 9.0 1.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Alpha-2-MRAP_C PF06401.6 CBK21160.2 - 0.069 12.9 14.0 0.89 9.3 0.3 2.4 1 1 2 3 3 2 0 Alpha-2-macroglobulin RAP, C-terminal domain ApoLp-III PF07464.6 CBK21160.2 - 0.07 13.1 11.2 0.12 12.3 7.8 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.16 CBK21160.2 - 0.07 12.6 8.7 0.097 12.2 6.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HrpB7 PF09486.5 CBK21160.2 - 0.084 12.8 5.9 0.42 10.5 0.3 2.5 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.1 CBK21160.2 - 0.085 12.8 17.3 0.071 13.0 8.0 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.10 CBK21160.2 - 0.086 12.0 11.1 0.13 11.4 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HlyD PF00529.15 CBK21160.2 - 0.1 11.9 6.0 0.12 11.6 4.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Ax_dynein_light PF10211.4 CBK21160.2 - 0.11 12.3 19.6 0.081 12.7 9.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain ALMT PF11744.3 CBK21160.2 - 0.14 10.8 3.3 0.16 10.5 2.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.1 CBK21160.2 - 0.14 11.1 10.0 0.18 10.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 CBK21160.2 - 0.18 12.2 11.9 1.9 8.9 3.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.14 CBK21160.2 - 0.19 9.5 11.3 0.23 9.2 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MRP-S26 PF14943.1 CBK21160.2 - 0.21 11.1 12.8 0.28 10.7 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Reo_sigmaC PF04582.7 CBK21160.2 - 0.21 10.7 5.4 0.35 10.0 3.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Uds1 PF15456.1 CBK21160.2 - 0.24 11.4 14.9 0.2 11.6 9.5 1.4 1 1 0 1 1 1 0 Up-regulated During Septation DUF948 PF06103.6 CBK21160.2 - 0.3 10.9 10.3 0.29 10.9 3.0 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF684 PF05075.9 CBK21160.2 - 0.3 9.6 6.2 0.079 11.5 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF684) Sec8_exocyst PF04048.9 CBK21160.2 - 0.33 10.5 15.7 1 8.9 3.6 2.6 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain IFT57 PF10498.4 CBK21160.2 - 0.35 9.5 15.9 0.46 9.1 11.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 bZIP_1 PF00170.16 CBK21160.2 - 0.36 10.8 15.7 0.13 12.2 3.6 3.2 2 1 1 3 3 3 0 bZIP transcription factor Mnd1 PF03962.10 CBK21160.2 - 0.39 10.3 20.8 0.7 9.5 2.0 2.0 1 1 1 2 2 2 0 Mnd1 family RmuC PF02646.11 CBK21160.2 - 0.4 9.4 12.5 0.097 11.4 3.7 2.0 1 1 1 2 2 2 0 RmuC family TBPIP PF07106.8 CBK21160.2 - 0.46 10.0 20.1 47 3.4 13.9 2.2 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 CBK21160.2 - 0.46 9.4 22.1 0.7 8.8 14.9 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4515 PF14988.1 CBK21160.2 - 0.5 9.9 20.3 0.041 13.5 8.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) DUF3490 PF11995.3 CBK21160.2 - 0.51 9.8 7.7 0.49 9.9 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) HSCB_C PF07743.8 CBK21160.2 - 0.56 10.6 12.7 0.97 9.9 2.1 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1515 PF07439.6 CBK21160.2 - 0.58 9.9 6.9 0.82 9.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Ead_Ea22 PF13935.1 CBK21160.2 - 0.58 10.4 10.3 27 5.0 7.1 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein DASH_Dam1 PF08653.5 CBK21160.2 - 0.63 9.8 2.2 7.2 6.4 0.3 2.7 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF3138 PF11336.3 CBK21160.2 - 0.66 8.0 2.1 2.6 6.1 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF445 PF04286.7 CBK21160.2 - 0.69 9.3 8.5 0.88 9.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Bacillus_HBL PF05791.6 CBK21160.2 - 0.7 9.2 15.2 0.63 9.3 3.6 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TFR_dimer PF04253.10 CBK21160.2 - 0.79 9.3 4.6 3.6 7.1 0.1 2.7 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain Snapin_Pallidin PF14712.1 CBK21160.2 - 1 9.7 15.1 1.1 9.6 4.6 3.0 1 1 2 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.5 CBK21160.2 - 1.1 9.3 16.7 2.9 8.0 11.4 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.6 CBK21160.2 - 1.1 9.0 16.2 3 7.7 11.1 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Lectin_N PF03954.9 CBK21160.2 - 1.2 8.5 11.3 0.76 9.1 5.1 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Phage_GPO PF05929.6 CBK21160.2 - 1.2 8.3 12.7 2 7.5 8.8 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GLE1 PF07817.8 CBK21160.2 - 1.3 7.8 11.2 1.4 7.8 3.9 1.8 1 1 1 2 2 2 0 GLE1-like protein DUF1664 PF07889.7 CBK21160.2 - 1.4 8.7 12.3 2 8.2 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 CBK21160.2 - 1.4 9.1 19.4 33 4.7 13.5 2.2 1 1 0 1 1 1 0 Syntaxin Mod_r PF07200.8 CBK21160.2 - 1.5 8.6 19.0 9.1 6.1 13.3 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HAUS6_N PF14661.1 CBK21160.2 - 1.7 7.9 12.5 3 7.1 8.6 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cytochrom_B562 PF07361.6 CBK21160.2 - 1.7 9.0 10.7 6.2 7.2 0.8 2.1 1 1 1 2 2 2 0 Cytochrome b562 DNA_topoisoIV PF00521.15 CBK21160.2 - 1.7 7.3 10.3 2.1 7.1 7.1 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DREPP PF05558.7 CBK21160.2 - 2 8.2 11.9 0.3 10.9 3.4 2.3 1 1 0 2 2 2 0 DREPP plasma membrane polypeptide Phage_GP20 PF06810.6 CBK21160.2 - 2.1 7.7 21.5 9.5 5.6 14.7 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fzo_mitofusin PF04799.8 CBK21160.2 - 2.2 7.6 12.3 1.2 8.4 4.9 2.2 1 1 0 2 2 2 0 fzo-like conserved region Laminin_II PF06009.7 CBK21160.2 - 2.2 8.0 14.9 2 8.1 7.2 2.0 1 1 1 2 2 2 0 Laminin Domain II YlqD PF11068.3 CBK21160.2 - 2.3 8.2 17.9 0.42 10.6 8.2 2.0 1 1 1 2 2 2 0 YlqD protein RRF PF01765.14 CBK21160.2 - 2.4 7.5 15.9 5.3 6.4 5.7 2.3 1 1 2 3 3 3 0 Ribosome recycling factor COG2 PF06148.6 CBK21160.2 - 2.5 7.9 14.8 7.4 6.4 1.0 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4559 PF15112.1 CBK21160.2 - 2.9 6.9 14.0 14 4.7 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Phage_DsbA PF11126.3 CBK21160.2 - 3 7.9 7.4 0.83 9.7 2.3 2.1 1 1 1 2 2 1 0 Transcriptional regulator DsbA V-ATPase_G PF03179.10 CBK21160.2 - 3 8.1 16.2 9.7 6.5 4.4 3.0 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit GrpE PF01025.14 CBK21160.2 - 3.2 7.2 15.9 14 5.1 10.5 2.2 1 1 0 1 1 1 0 GrpE TMCO5 PF14992.1 CBK21160.2 - 3.2 6.7 18.5 4.5 6.3 12.8 1.2 1 0 0 1 1 1 0 TMCO5 family DUF3810 PF12725.2 CBK21160.2 - 3.4 6.4 9.0 0.87 8.4 3.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF972 PF06156.8 CBK21160.2 - 3.6 7.9 16.7 2.4 8.5 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HSP70 PF00012.15 CBK21160.2 - 3.7 5.3 15.3 3.7 5.3 10.1 1.3 1 1 0 1 1 1 0 Hsp70 protein NPV_P10 PF05531.7 CBK21160.2 - 4 7.7 10.9 5e+02 1.0 7.6 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 CBK21160.2 - 4.3 7.7 12.7 3.8 7.9 2.6 3.2 1 1 2 3 3 3 0 SlyX DUF3373 PF11853.3 CBK21160.2 - 4.3 5.7 11.5 1 7.8 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) RP-C_C PF11800.3 CBK21160.2 - 4.6 6.8 11.4 9 5.9 7.9 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region CENP-Q PF13094.1 CBK21160.2 - 4.6 7.2 22.0 1.4e+02 2.4 15.4 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Swi5 PF07061.6 CBK21160.2 - 4.8 7.0 10.7 0.97 9.2 2.9 2.5 2 1 0 2 2 2 0 Swi5 AAA_23 PF13476.1 CBK21160.2 - 5.5 7.2 17.0 8.2 6.6 11.8 1.3 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.7 CBK21160.2 - 5.6 6.6 13.8 7.3 6.2 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Prefoldin PF02996.12 CBK21160.2 - 5.9 6.5 18.1 2 8.0 3.6 3.6 1 1 4 5 5 5 0 Prefoldin subunit LMBR1 PF04791.11 CBK21160.2 - 6.1 5.3 10.0 7.9 4.9 6.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.4 CBK21160.2 - 6.8 6.9 12.1 2.2e+02 2.0 8.4 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CCDC-167 PF15188.1 CBK21160.2 - 7 6.6 17.8 1.4 8.8 0.8 2.8 1 1 1 2 2 1 0 Coiled-coil domain-containing protein 167 S_layer_C PF05124.7 CBK21160.2 - 7.1 6.1 10.5 8.8 5.8 7.3 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region P4Ha_N PF08336.6 CBK21160.2 - 8.6 6.1 13.0 1.6 8.5 3.8 2.7 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Bap31 PF05529.7 CBK21160.2 - 8.9 5.7 20.4 1.2 8.5 4.2 2.4 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like TEX13 PF15186.1 CBK21160.2 - 9.1 5.8 10.6 1.4 8.4 2.5 2.1 1 1 2 3 3 3 0 Testis-expressed sequence 13 protein family Allexi_40kDa PF05549.6 CBK21160.2 - 9.2 5.4 11.9 8.3 5.6 4.6 1.8 1 1 2 3 3 3 0 Allexivirus 40kDa protein DivIC PF04977.10 CBK21160.2 - 9.3 5.8 24.6 0.079 12.4 3.7 3.6 2 1 2 4 4 3 0 Septum formation initiator ADIP PF11559.3 CBK21160.2 - 9.4 6.1 22.0 30 4.4 12.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YtxH PF12732.2 CBK21160.2 - 9.6 6.6 17.1 8.8e+03 -2.9 11.8 2.9 1 1 0 1 1 0 0 YtxH-like protein FHA PF00498.21 CBK21161.2 - 2.8e-07 30.5 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain CAF1 PF04857.15 CBK21163.2 - 2.3e-59 200.8 0.3 4e-59 200.0 0.2 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 CBK21163.2 - 0.0061 16.0 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease RNase_H_2 PF13482.1 CBK21163.2 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 RNase_H superfamily Ras PF00071.17 CBK21164.2 - 6.8e-38 129.6 0.5 8.3e-38 129.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK21164.2 - 1.1e-15 58.1 0.1 1.6e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK21164.2 - 3.5e-15 55.6 0.6 4.3e-15 55.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK21164.2 - 1.5e-06 27.8 0.8 0.00014 21.3 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBK21164.2 - 7.8e-06 25.1 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBK21164.2 - 9.5e-06 24.9 0.4 1.2e-05 24.5 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBK21164.2 - 0.0002 21.3 0.1 0.00031 20.6 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBK21164.2 - 0.00061 19.9 0.0 0.0022 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CBK21164.2 - 0.0013 18.1 0.6 0.14 11.5 0.4 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 CBK21164.2 - 0.015 14.0 1.0 2.4 6.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 CBK21164.2 - 0.037 14.0 0.0 0.048 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF2726 PF10881.3 CBK21164.2 - 0.042 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) FeoB_N PF02421.13 CBK21164.2 - 0.076 12.2 0.4 0.48 9.6 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B HSP90 PF00183.13 CBK21165.2 - 1.3e-231 769.6 31.5 1.7e-231 769.2 21.8 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CBK21165.2 - 1.1e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK21165.2 - 1.5e-11 44.1 0.1 4.8e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tom37_C PF11801.3 CBK21165.2 - 7.9 6.3 8.6 12 5.6 2.0 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain RRM_6 PF14259.1 CBK21166.2 - 7.6e-35 118.7 0.0 5.2e-19 67.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK21166.2 - 9.6e-35 118.0 0.0 3.6e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21166.2 - 2.6e-09 36.7 0.1 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK21166.2 - 0.015 15.0 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DNA_topoisoIV PF00521.15 CBK21166.2 - 0.015 14.1 1.3 0.13 11.0 0.6 2.0 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A RNA_pol_Rpc4 PF05132.9 CBK21166.2 - 0.89 9.5 7.9 3 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 LRR_8 PF13855.1 CBK21167.2 - 0.059 13.1 2.8 2.4 7.9 0.6 2.8 2 1 0 2 2 2 0 Leucine rich repeat AAA PF00004.24 CBK21168.2 - 1.6e-40 138.3 0.0 6.3e-40 136.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBK21168.2 - 3.1e-06 27.2 0.2 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBK21168.2 - 4.5e-06 26.8 0.1 0.00033 20.8 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CBK21168.2 - 9.1e-06 25.4 0.0 0.00012 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBK21168.2 - 5.3e-05 23.2 0.1 0.0002 21.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBK21168.2 - 0.0014 18.3 0.1 0.0046 16.6 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 CBK21168.2 - 0.0016 18.5 0.0 0.071 13.2 0.0 2.9 2 1 0 2 2 2 1 RNA helicase DUF815 PF05673.8 CBK21168.2 - 0.0026 16.7 0.0 0.0064 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBK21168.2 - 0.0037 17.1 0.0 0.049 13.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CBK21168.2 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBK21168.2 - 0.0083 16.9 0.1 0.023 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBK21168.2 - 0.019 14.9 0.1 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK21168.2 - 0.021 14.5 1.9 9.7 5.8 0.0 3.3 2 2 1 3 3 3 0 Archaeal ATPase AAA_33 PF13671.1 CBK21168.2 - 0.022 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBK21168.2 - 0.033 13.3 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CBK21168.2 - 0.04 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CBK21168.2 - 0.043 13.4 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBK21168.2 - 0.062 12.8 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBK21168.2 - 0.063 13.5 0.1 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 CBK21168.2 - 0.069 13.2 0.9 0.29 11.2 0.2 2.4 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mg_chelatase PF01078.16 CBK21168.2 - 0.082 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TBPIP PF07106.8 CBK21168.2 - 0.11 12.0 1.7 0.23 10.9 0.8 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4094 PF13334.1 CBK21168.2 - 0.13 12.6 1.9 44 4.5 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) AAA_25 PF13481.1 CBK21168.2 - 0.15 11.4 1.0 1.6 8.0 0.1 2.7 2 1 0 3 3 3 0 AAA domain RRM_2 PF04059.7 CBK21169.2 - 1.3e-22 79.5 0.0 2.6e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_6 PF14259.1 CBK21169.2 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK21169.2 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UNC-50 PF05216.8 CBK21170.2 - 3e-57 193.5 18.1 3.3e-57 193.3 12.5 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1129 PF06570.6 CBK21170.2 - 0.28 10.4 7.7 0.069 12.4 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) COX2-transmemb PF09125.5 CBK21170.2 - 1.5 8.4 7.3 1.7 8.2 1.3 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane COX14 PF14880.1 CBK21170.2 - 2 8.0 4.4 8.8 6.0 0.6 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly NfeD PF01957.13 CBK21170.2 - 4 7.5 10.1 2.7 8.1 0.1 2.7 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding WD40 PF00400.27 CBK21171.2 - 1.6e-14 53.1 0.1 0.023 14.5 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBK21171.2 - 0.00047 19.6 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain IKI3 PF04762.7 CBK21171.2 - 0.0035 15.2 0.3 3.9 5.1 0.0 3.0 1 1 1 3 3 3 1 IKI3 family CDRT4 PF15213.1 CBK21171.2 - 0.024 14.7 0.4 0.04 14.0 0.3 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein CDC45 PF02724.9 CBK21171.2 - 0.045 11.7 17.9 0.064 11.2 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PQQ PF01011.16 CBK21171.2 - 0.079 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF2138 PF09909.4 CBK21171.2 - 0.08 11.0 0.1 0.11 10.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Drc1-Sld2 PF11719.3 CBK21171.2 - 0.081 12.0 10.2 0.11 11.5 7.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.7 CBK21171.2 - 0.099 10.5 18.6 0.14 10.0 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 CBK21171.2 - 0.26 10.2 19.1 0.36 9.8 13.2 1.1 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 CBK21171.2 - 4 6.0 16.5 7.3 5.2 11.4 1.3 1 0 0 1 1 1 0 Paf1 Ank_2 PF12796.2 CBK21172.2 - 5.4e-25 87.5 3.7 2.2e-14 53.5 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21172.2 - 4.2e-19 67.3 7.4 6.2e-07 28.9 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBK21172.2 - 2.1e-18 65.9 2.4 9.4e-08 32.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK21172.2 - 8.8e-14 50.2 9.7 4.7e-05 23.2 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 CBK21172.2 - 1.3e-10 41.4 4.8 3.5e-07 30.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Collagen PF01391.13 CBK21172.2 - 0.0027 17.2 8.1 0.0027 17.2 5.6 1.6 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Hid1 PF12722.2 CBK21172.2 - 0.16 9.6 0.1 0.2 9.3 0.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 CBK21172.2 - 7.4 4.1 23.3 11 3.5 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FliJ PF02050.11 CBK21173.2 - 0.058 13.4 0.4 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein DUF773 PF05600.7 CBK21174.2 - 0.023 13.5 0.1 0.58 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF773) MSP1_C PF07462.6 CBK21174.2 - 2.7 6.2 4.4 4.4 5.5 3.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 CBK21174.2 - 9.6 5.3 8.3 15 4.6 5.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_5 PF13202.1 CBK21175.2 - 2.3e-09 36.1 0.1 0.00047 19.3 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 CBK21175.2 - 3.4e-09 35.3 0.0 0.00042 19.4 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 CBK21175.2 - 1.6e-08 34.1 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBK21175.2 - 6.5e-08 32.5 0.1 2e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBK21175.2 - 8.5e-08 31.4 0.0 0.0053 16.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBK21175.2 - 4.8e-06 26.0 0.5 0.011 15.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBK21175.2 - 0.0041 17.1 0.2 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CBK21175.2 - 0.027 14.1 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 EF hand S1 PF00575.18 CBK21175.2 - 0.038 14.0 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Pescadillo_N PF06732.6 CBK21176.2 - 2.2e-107 358.5 1.0 2.9e-107 358.1 0.7 1.1 1 0 0 1 1 1 1 Pescadillo N-terminus Sec8_exocyst PF04048.9 CBK21176.2 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain BRCT PF00533.21 CBK21177.2 - 9.3e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HemX PF04375.9 CBK21177.2 - 2.8 6.4 11.7 4.2 5.8 8.1 1.2 1 0 0 1 1 1 0 HemX DUF416 PF04222.7 CBK21177.2 - 9.2 5.3 11.6 16 4.6 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF416) zf-C3HC4_3 PF13920.1 CBK21178.2 - 6.9e-14 51.2 18.6 6.9e-14 51.2 12.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK21178.2 - 6.5e-06 26.0 20.4 6.5e-06 26.0 14.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK21178.2 - 0.00067 19.4 20.3 0.0021 17.8 14.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBK21178.2 - 0.011 15.4 18.8 0.034 13.8 13.0 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Nop16 PF09420.5 CBK21179.2 - 3.6e-11 43.4 0.3 4.1e-11 43.2 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Ribosomal_L7Ae PF01248.21 CBK21180.2 - 1.7e-24 85.1 0.1 2e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Abhydrolase_6 PF12697.2 CBK21181.2 - 2e-05 24.5 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBK21181.2 - 7.6e-05 22.4 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBK21181.2 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 CBK21181.2 - 0.0015 18.2 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CBK21181.2 - 0.078 12.1 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family PFK PF00365.15 CBK21183.2 - 3.3e-13 49.2 0.0 1.8e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Phosphofructokinase N2227 PF07942.7 CBK21185.2 - 8.5e-81 270.8 0.1 9.6e-81 270.7 0.1 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CBK21185.2 - 0.0008 19.1 0.1 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK21185.2 - 0.0018 18.7 0.0 0.0079 16.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Relaxase PF03432.9 CBK21185.2 - 0.035 13.4 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Methyltransf_18 PF12847.2 CBK21185.2 - 0.05 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CBK21185.2 - 0.084 13.3 0.0 0.78 10.2 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain Pept_tRNA_hydro PF01195.14 CBK21186.2 - 2.6e-38 131.3 0.0 9.4e-37 126.2 0.0 2.1 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase NPL4 PF05021.10 CBK21187.2 - 5.2e-26 91.5 0.0 8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CBK21187.2 - 1.1e-11 44.5 10.5 1.1e-11 44.5 7.3 3.4 1 1 2 3 3 3 2 NPL4 family, putative zinc binding region DHODB_Fe-S_bind PF10418.4 CBK21187.2 - 7.9 6.0 17.3 4 7.0 0.4 4.8 5 0 0 5 5 5 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Pkinase PF00069.20 CBK21189.2 - 1e-45 155.9 0.0 1.2e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21189.2 - 4.4e-29 101.3 0.0 5.4e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mis12 PF05859.7 CBK21189.2 - 0.056 13.2 0.4 0.099 12.4 0.0 1.5 2 0 0 2 2 2 0 Mis12 protein Kinase-like PF14531.1 CBK21189.2 - 0.1 11.5 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CBK21189.2 - 0.12 11.1 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UQ_con PF00179.21 CBK21190.2 - 3.3e-48 162.6 0.0 4.1e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK21190.2 - 7.9e-06 25.6 0.0 9.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK21190.2 - 0.0038 17.0 0.0 0.005 16.7 0.0 1.5 1 1 0 1 1 1 1 RWD domain DEAD PF00270.24 CBK21191.2 - 1e-37 129.2 0.0 2.4e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21191.2 - 5e-21 74.3 0.0 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-met PF12874.2 CBK21191.2 - 0.00036 20.6 1.4 0.00074 19.6 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Helicase_C_2 PF13307.1 CBK21191.2 - 0.00091 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain CpXC PF14353.1 CBK21191.2 - 0.023 14.6 0.3 0.063 13.2 0.2 1.7 1 0 0 1 1 1 0 CpXC protein zf-C2H2_jaz PF12171.3 CBK21191.2 - 0.032 14.3 0.4 0.032 14.3 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBK21191.2 - 0.071 13.4 0.8 0.071 13.4 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Neur_chan_memb PF02932.11 CBK21191.2 - 0.56 10.0 6.4 1.6 8.5 0.8 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L32e PF01655.13 CBK21192.2 - 2.7e-46 156.1 0.3 3.4e-46 155.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 RNase_T PF00929.19 CBK21193.2 - 2.1e-13 50.9 0.0 2.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBK21193.2 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease TFIID-31kDa PF02291.10 CBK21194.2 - 2.9e-12 46.5 0.1 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CBK21194.2 - 0.0066 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CBK21194.2 - 0.013 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Ribosomal_L2_C PF03947.13 CBK21195.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK21195.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain H_PPase PF03030.11 CBK21196.2 - 3.6e-257 855.0 27.1 4.1e-257 854.8 18.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Put_DNA-bind_N PF06971.8 CBK21197.2 - 1.9 8.2 4.6 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus LMBR1 PF04791.11 CBK21198.2 - 1.3e-08 33.8 0.7 1.5e-08 33.7 0.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4179 PF13786.1 CBK21198.2 - 0.013 15.7 0.8 0.024 14.8 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Fib_alpha PF08702.5 CBK21198.2 - 0.32 11.1 4.1 0.15 12.1 1.4 1.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 CBK21200.2 - 4e-36 123.2 10.9 1.7e-14 53.8 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBK21200.2 - 4.8e-30 102.9 6.0 4e-09 36.4 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBK21200.2 - 7.6e-30 102.7 5.8 5.9e-11 42.5 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 CBK21200.2 - 1.2e-26 91.1 9.9 5.8e-07 29.0 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 CBK21200.2 - 5.1e-23 78.8 5.1 4.5e-05 23.3 0.0 6.2 7 1 0 7 7 7 5 Ankyrin repeat Ribosomal_L7Ae PF01248.21 CBK21201.2 - 3e-25 87.5 0.2 3.7e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_hydro_85 PF03644.8 CBK21202.2 - 4.1e-51 173.9 0.0 5.6e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF3565 PF12088.3 CBK21203.2 - 0.028 14.1 1.3 0.068 12.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) WD40 PF00400.27 CBK21204.2 - 1.7e-05 24.4 6.9 0.18 11.7 0.7 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF837 PF05769.6 CBK21204.2 - 0.035 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) PH_8 PF15409.1 CBK21205.2 - 1.2e-06 28.4 0.1 1.9e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CBK21205.2 - 1.5e-05 25.1 0.1 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK21205.2 - 0.00069 19.8 0.6 0.0045 17.2 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Band_7 PF01145.20 CBK21206.2 - 2.9e-30 105.5 0.4 7.1e-30 104.2 0.3 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBK21206.2 - 0.0055 16.2 0.3 0.0091 15.5 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Ribul_P_3_epim PF00834.14 CBK21207.2 - 1.9e-67 226.3 0.3 2.2e-67 226.1 0.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 CBK21207.2 - 0.0093 15.2 0.6 0.015 14.5 0.4 1.3 1 1 0 1 1 1 1 PcrB family QRPTase_C PF01729.14 CBK21207.2 - 0.022 14.3 0.2 0.031 13.7 0.1 1.5 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Bac_luciferase PF00296.15 CBK21207.2 - 0.13 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Band_7 PF01145.20 CBK21208.2 - 3.3e-30 105.2 0.4 7.1e-30 104.2 0.3 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBK21208.2 - 0.0054 16.2 0.3 0.0091 15.5 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.20 CBK21209.2 - 9.5e-25 87.5 8.9 6.6e-24 84.7 6.2 2.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family DivIVA PF05103.8 CBK21209.2 - 0.0039 17.2 4.8 0.0073 16.3 3.3 1.4 1 0 0 1 1 1 1 DivIVA protein SUKH_5 PF14567.1 CBK21209.2 - 0.082 12.3 0.2 0.6 9.5 0.0 2.2 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall Caudo_TAP PF02413.12 CBK21209.2 - 0.24 11.5 4.5 1.7 8.8 3.1 2.1 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein V-ATPase_G PF03179.10 CBK21209.2 - 0.94 9.8 11.8 0.11 12.8 2.7 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CBK21209.2 - 1.1 9.0 10.0 0.32 10.8 3.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) ArfGap PF01412.13 CBK21210.2 - 3.1e-19 68.8 1.4 7.9e-19 67.5 0.9 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Daxx PF03344.10 CBK21210.2 - 0.23 9.9 11.6 0.29 9.5 8.1 1.1 1 0 0 1 1 1 0 Daxx Family YchF-GTPase_C PF06071.8 CBK21211.2 - 4e-39 132.2 1.0 1e-38 130.9 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBK21211.2 - 1.5e-16 60.3 0.0 3.2e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK21211.2 - 8.5e-07 28.3 0.0 2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CBK21211.2 - 0.0074 17.1 0.0 0.03 15.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 CBK21211.2 - 0.0089 14.8 0.1 0.022 13.5 0.0 1.6 2 0 0 2 2 2 1 ArgK protein TGS PF02824.16 CBK21211.2 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 TGS domain AAA_18 PF13238.1 CBK21211.2 - 0.023 15.0 0.0 0.18 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CBK21211.2 - 0.068 12.9 0.0 0.9 9.3 0.0 2.7 1 1 0 1 1 1 0 Dynamin family MRP-S31 PF15433.1 CBK21211.2 - 0.11 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DEAD PF00270.24 CBK21212.2 - 5.1e-47 159.4 0.0 1.6e-45 154.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21212.2 - 3e-26 91.0 0.4 1.2e-25 89.1 0.2 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21212.2 - 0.0013 18.5 0.0 0.004 17.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CBK21212.2 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain GRP PF07172.6 CBK21212.2 - 3 8.3 17.4 0.096 13.1 5.2 2.4 2 0 0 2 2 2 0 Glycine rich protein family DUF566 PF04484.7 CBK21212.2 - 8.3 5.8 21.9 12 5.2 15.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) PHD PF00628.24 CBK21213.2 - 1.6e-09 37.3 58.0 5.9e-05 22.6 7.7 4.3 4 0 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.1 CBK21213.2 - 0.0096 16.0 50.0 0.022 14.8 8.6 3.9 1 1 2 3 3 3 1 PHD-like zinc-binding domain zf-RING_2 PF13639.1 CBK21213.2 - 0.019 14.7 6.2 0.019 14.7 4.3 4.6 2 2 2 4 4 4 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 CBK21213.2 - 0.034 14.1 42.0 0.039 13.9 14.8 3.3 1 1 2 3 3 3 0 PHD-zinc-finger like domain DUF563 PF04577.9 CBK21214.2 - 3.4e-15 56.5 1.3 5.6e-15 55.8 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DUF3760 PF12586.3 CBK21214.2 - 1.4 8.8 4.2 2.8 7.8 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3760) Nucleotid_trans PF03407.11 CBK21215.2 - 2.1e-20 73.4 0.1 3.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1371 PF07115.6 CBK21215.2 - 0.5 10.5 6.1 0.83 9.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1371) Glyco_transf_49 PF13896.1 CBK21216.2 - 3.6e-09 36.1 4.3 1.2e-07 31.1 0.4 2.7 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK21216.2 - 0.00037 20.2 1.0 0.0012 18.5 0.3 2.0 1 1 1 2 2 2 2 F-box associated Ku_PK_bind PF08785.6 CBK21217.2 - 0.057 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like RNase_P_pop3 PF08228.6 CBK21217.2 - 0.065 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.21 CBK21218.2 - 0.018 14.5 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FadA PF09403.5 CBK21219.2 - 0.079 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA RNA_helicase PF00910.17 CBK21220.2 - 7e-10 39.0 0.1 3.9e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 CBK21220.2 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK21220.2 - 0.059 13.0 0.3 1.1 8.9 0.0 2.8 3 1 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 CBK21221.2 - 7.5e-09 35.7 0.0 3.2e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 CBK21221.2 - 0.064 12.9 0.1 0.88 9.2 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 CBK21221.2 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 CBK21222.2 - 4.6e-79 265.3 1.6 6.4e-79 264.8 1.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK21222.2 - 4.8e-17 61.5 0.0 2.4e-16 59.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBK21222.2 - 1.2e-11 43.9 0.1 4.3e-11 42.1 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBK21222.2 - 1.1e-07 31.4 0.0 4.1e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK21222.2 - 1.5e-06 28.1 0.0 3.5e-05 23.7 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2522 PF10747.4 CBK21222.2 - 0.00095 19.2 2.0 0.0019 18.2 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2522) Arch_ATPase PF01637.13 CBK21222.2 - 0.009 15.7 1.7 0.9 9.1 0.0 3.2 4 0 0 4 4 4 1 Archaeal ATPase AAA_14 PF13173.1 CBK21222.2 - 0.05 13.4 0.1 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBK21222.2 - 0.22 11.6 1.4 2 8.5 0.0 3.2 3 2 0 3 3 3 0 AAA domain Ribosomal_S26e PF01283.14 CBK21223.2 - 2.6e-44 150.1 7.7 2.9e-44 149.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 CBK21223.2 - 0.0005 20.4 0.9 0.02 15.2 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP19 PF01922.12 CBK21223.2 - 0.0069 16.9 0.4 0.0095 16.4 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein Fer4_6 PF12837.2 CBK21223.2 - 0.017 14.9 3.0 0.059 13.2 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBK21223.2 - 0.019 14.7 0.8 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain RNA_pol_N PF01194.12 CBK21223.2 - 0.033 14.1 2.0 0.072 13.1 1.4 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.4 CBK21223.2 - 0.034 13.2 0.7 0.085 11.9 0.5 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Fer4_19 PF06902.6 CBK21223.2 - 0.06 13.1 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 CBK21223.2 - 0.07 12.7 3.5 0.087 12.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 CBK21223.2 - 0.37 10.8 4.1 0.49 10.4 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 CBK21223.2 - 0.6 10.1 4.1 2.6 8.1 2.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK21223.2 - 1.2 9.4 5.5 3.1 8.1 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK21223.2 - 5.4 7.6 8.5 1.8 9.0 2.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain MAP65_ASE1 PF03999.7 CBK21224.2 - 1.8e-06 26.8 6.8 2.3e-06 26.5 4.7 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MAP65_ASE1 PF03999.7 CBK21225.2 - 1.2e-13 50.5 20.5 1.7e-13 50.1 14.2 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 CBK21225.2 - 0.0013 18.5 2.2 0.0013 18.5 1.5 2.9 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 CBK21225.2 - 0.046 13.1 0.5 0.046 13.1 0.4 3.0 2 1 1 3 3 3 0 fzo-like conserved region DUF4279 PF14106.1 CBK21225.2 - 0.16 11.8 1.4 3.4 7.5 0.0 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4279) DUF896 PF05979.7 CBK21225.2 - 0.55 9.8 5.7 8.1 6.1 0.2 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) EF-hand_2 PF09068.6 CBK21225.2 - 1.3 9.0 5.9 5 7.1 2.4 2.7 2 1 0 2 2 2 0 EF hand ATP-synt_C PF00137.16 CBK21226.2 - 6.2e-24 83.6 15.7 5.9e-15 54.9 6.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C HCV_NS4b PF01001.14 CBK21226.2 - 1.1 8.6 7.5 4.4 6.6 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b QueT PF06177.6 CBK21226.2 - 3.6 7.5 11.4 0.93 9.4 0.2 2.8 2 1 0 3 3 3 0 QueT transporter YEATS PF03366.11 CBK21227.2 - 1.8e-27 94.8 0.1 2.3e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 YEATS family Fe_hyd_SSU PF02256.12 CBK21227.2 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Iron hydrogenase small subunit UCH PF00443.24 CBK21228.2 - 7.2e-48 163.0 0.0 8.8e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21228.2 - 4e-13 49.4 0.0 9.1e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBK21228.2 - 0.08 12.2 0.1 0.4 9.9 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ubiquitin PF00240.18 CBK21228.2 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DKCLD PF08068.7 CBK21229.2 - 5.6e-31 106.2 0.9 9.6e-30 102.3 0.1 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 CBK21229.2 - 3.6e-21 75.8 7.2 4.4e-20 72.3 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CBK21229.2 - 4.3e-21 74.4 1.7 9.1e-21 73.3 1.2 1.6 1 0 0 1 1 1 1 PUA domain eIF_4EBP PF05456.6 CBK21229.2 - 1.9 8.2 6.5 4.2 7.0 4.5 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CDC45 PF02724.9 CBK21229.2 - 7 4.5 14.4 9 4.1 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 CBK21229.2 - 7.6 6.3 17.4 12 5.7 12.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.3 CBK21229.2 - 8.8 4.7 18.1 13 4.2 12.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 14-3-3 PF00244.15 CBK21230.2 - 3.5e-87 291.4 3.3 3.9e-87 291.2 2.3 1.0 1 0 0 1 1 1 1 14-3-3 protein YfhD PF14151.1 CBK21230.2 - 0.12 12.5 0.2 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 YfhD-like protein ATG16 PF08614.6 CBK21231.2 - 3.6e-05 23.6 13.6 4.5e-05 23.3 9.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF241 PF03087.9 CBK21231.2 - 0.00054 19.5 2.4 0.00054 19.5 1.7 1.7 1 1 1 2 2 2 1 Arabidopsis protein of unknown function CCDC92 PF14916.1 CBK21231.2 - 0.0042 16.6 1.3 0.0042 16.6 0.9 1.8 2 0 0 2 2 2 1 Coiled-coil domain of unknown function IncA PF04156.9 CBK21231.2 - 0.006 16.2 17.9 0.0079 15.8 12.4 1.1 1 0 0 1 1 1 1 IncA protein CALCOCO1 PF07888.6 CBK21231.2 - 0.022 13.0 12.2 0.026 12.8 8.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med14 PF08638.6 CBK21231.2 - 0.033 13.4 0.6 0.038 13.2 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 DUF4201 PF13870.1 CBK21231.2 - 0.056 12.8 14.3 0.13 11.6 9.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) SDP_N PF12278.3 CBK21231.2 - 0.13 11.9 4.3 0.035 13.7 1.1 1.5 1 1 1 2 2 2 0 Sex determination protein N terminal DUF496 PF04363.7 CBK21231.2 - 0.16 11.7 3.3 0.18 11.6 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF496) TSC22 PF01166.13 CBK21231.2 - 0.29 11.1 11.9 0.038 13.9 4.5 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 CBK21231.2 - 0.38 8.5 7.5 0.41 8.4 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40_alt PF14077.1 CBK21231.2 - 0.54 9.9 4.6 1 9.0 2.7 1.9 1 1 0 1 1 1 0 Alternative WD40 repeat motif EMP24_GP25L PF01105.19 CBK21231.2 - 0.72 9.5 5.5 1 9.0 3.8 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF812 PF05667.6 CBK21231.2 - 0.76 8.2 16.1 0.91 7.9 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 CBK21231.2 - 0.92 9.1 12.6 1.3 8.6 8.7 1.3 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 CBK21231.2 - 1.1 8.2 17.4 1.3 8.0 12.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2968 PF11180.3 CBK21231.2 - 1.4 8.2 10.8 2.5 7.4 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF848 PF05852.6 CBK21231.2 - 1.4 8.7 10.5 2.3 8.0 7.3 1.5 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ERM PF00769.14 CBK21231.2 - 2.4 7.6 19.1 4.2 6.8 13.2 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 CBK21231.2 - 2.8 8.3 13.4 0.26 11.6 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) UPF0449 PF15136.1 CBK21231.2 - 3.2 7.9 11.0 5.2 7.3 2.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF948 PF06103.6 CBK21231.2 - 3.8 7.4 6.9 1.6 8.6 2.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 CBK21231.2 - 4.5 7.2 19.2 17 5.3 13.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) GAS PF13851.1 CBK21231.2 - 4.8 6.3 19.4 14 4.8 13.3 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 CBK21231.2 - 6 6.6 21.0 12 5.6 14.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PEP-utilisers_N PF05524.8 CBK21231.2 - 6.7 6.5 7.6 33 4.2 4.1 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal ADIP PF11559.3 CBK21231.2 - 7 6.5 15.8 9.7 6.0 11.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 CBK21231.2 - 9.1 5.1 11.5 13 4.6 8.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 CBK21231.2 - 9.9 4.7 17.7 16 3.9 12.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein MORN PF02493.15 CBK21232.2 - 0.00057 19.4 6.3 0.0036 16.9 0.2 4.5 6 0 0 6 6 6 1 MORN repeat LRR_4 PF12799.2 CBK21232.2 - 0.0021 17.6 0.7 0.1 12.2 0.1 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK21232.2 - 0.13 12.0 0.5 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat MORN_2 PF07661.8 CBK21232.2 - 1.7 8.9 7.5 41 4.6 0.0 4.2 4 0 0 4 4 4 0 MORN repeat variant Ank_4 PF13637.1 CBK21234.2 - 3.7e-11 43.2 0.1 4.5e-06 27.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBK21234.2 - 8.4e-11 42.0 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21234.2 - 2.3e-09 36.6 0.0 0.00052 19.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CBK21234.2 - 1.2e-08 34.3 0.0 0.00027 20.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBK21234.2 - 2.3e-06 27.6 0.2 0.0029 17.7 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Trypan_PARP PF05887.6 CBK21234.2 - 0.21 11.3 11.7 0.36 10.6 8.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L11_N PF03946.9 CBK21235.2 - 5.5e-14 51.3 0.2 9e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBK21235.2 - 2.2e-12 46.9 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Rib_5-P_isom_A PF06026.9 CBK21235.2 - 0.068 12.4 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) STIL_N PF15253.1 CBK21235.2 - 0.14 10.8 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus DEAD PF00270.24 CBK21236.2 - 2.1e-22 79.3 0.0 9.2e-22 77.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21236.2 - 2e-15 56.4 0.1 4.4e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21236.2 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Snf7 PF03357.16 CBK21236.2 - 0.018 14.4 0.5 0.031 13.6 0.3 1.2 1 0 0 1 1 1 0 Snf7 AAA_22 PF13401.1 CBK21236.2 - 0.021 14.9 0.0 0.057 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_L13 PF00572.13 CBK21237.2 - 6e-32 110.3 0.3 6e-32 110.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L13 Glyco_trans_1_2 PF13524.1 CBK21237.2 - 0.29 11.4 3.6 0.16 12.2 1.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBK21238.2 - 1.2e-31 109.4 0.0 2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBK21238.2 - 2.4e-09 37.1 0.0 4.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 CBK21238.2 - 2.8e-08 33.9 0.0 5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBK21238.2 - 1.2e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CBK21238.2 - 1.9e-06 28.0 0.0 5.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CBK21238.2 - 0.00032 20.5 0.5 0.00081 19.2 0.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like Pkinase PF00069.20 CBK21239.2 - 4.6e-47 160.3 0.0 6.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Vps16_C PF04840.7 CBK21239.2 - 4.8e-25 88.1 0.4 7.1e-25 87.6 0.3 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Pkinase_Tyr PF07714.12 CBK21239.2 - 1.9e-09 36.9 0.0 5.2e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CBK21239.2 - 0.16 11.3 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Hemopexin PF00045.14 CBK21240.2 - 0.14 11.8 0.3 0.43 10.3 0.2 1.8 1 0 0 1 1 1 0 Hemopexin Prefoldin PF02996.12 CBK21241.2 - 1.2e-13 50.7 0.2 1.2e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit MORN PF02493.15 CBK21242.2 - 5.2e-23 79.3 49.8 9.5e-05 21.9 0.6 11.4 12 0 0 12 12 12 8 MORN repeat MORN_2 PF07661.8 CBK21242.2 - 3.1e-06 26.5 24.3 1.2 9.3 0.8 8.9 8 0 0 8 8 8 3 MORN repeat variant D-aminoacyl_C PF07908.7 CBK21242.2 - 3 7.2 6.0 14 5.0 0.4 3.6 2 1 1 3 3 3 0 D-aminoacylase, C-terminal region DEAD PF00270.24 CBK21243.2 - 2.5e-45 153.9 0.2 4.2e-45 153.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21243.2 - 2.7e-27 94.4 0.1 3.9e-26 90.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21243.2 - 5.7e-08 32.7 0.1 6.7e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3849 PF12960.2 CBK21243.2 - 0.065 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) CMS1 PF14617.1 CBK21243.2 - 0.11 11.5 0.0 0.11 11.5 0.0 2.6 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF563 PF04577.9 CBK21244.2 - 5.7e-17 62.3 2.2 6.6e-17 62.1 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Pkinase PF00069.20 CBK21245.2 - 5.3e-114 379.7 0.0 3.2e-61 206.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21245.2 - 2.5e-45 154.5 0.0 5.1e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBK21245.2 - 8.9e-11 41.2 0.0 0.00031 19.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CBK21245.2 - 7.4e-09 34.9 0.0 0.00018 20.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBK21245.2 - 9.4e-06 25.0 0.1 0.025 13.9 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBK21245.2 - 0.00019 20.3 0.2 0.37 9.5 0.0 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.18 CBK21245.2 - 0.0002 21.1 0.8 0.59 9.8 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBK21245.2 - 0.007 15.7 0.1 0.55 9.5 0.0 2.4 2 0 0 2 2 2 1 RIO1 family DUF572 PF04502.8 CBK21246.2 - 9.6e-67 225.5 15.6 1.1e-66 225.2 10.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 CBK21246.2 - 0.015 14.6 2.6 0.038 13.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.9 CBK21246.2 - 0.067 13.1 1.2 1.1 9.2 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-FCS PF06467.9 CBK21246.2 - 0.13 11.9 0.8 18 5.0 0.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 CBK21246.2 - 0.13 11.4 2.9 2.1 7.6 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain CAF-1_p150 PF11600.3 CBK21246.2 - 0.15 11.4 31.4 0.35 10.2 21.8 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 CBK21246.2 - 0.75 8.6 16.8 1 8.1 11.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zn_ribbon_recom PF13408.1 CBK21246.2 - 0.79 10.0 2.7 5.9 7.2 1.5 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain AAA_23 PF13476.1 CBK21246.2 - 0.93 9.7 15.7 1.5 9.0 10.8 1.5 1 0 0 1 1 1 0 AAA domain DUF501 PF04417.7 CBK21246.2 - 2 8.2 11.6 0.99 9.2 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF501) 6PF2K PF01591.13 CBK21247.2 - 2.3e-42 144.5 0.1 3.1e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CBK21247.2 - 5.9e-32 110.9 0.0 1.9e-31 109.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CBK21247.2 - 5.4e-08 33.6 0.1 4e-07 30.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBK21247.2 - 1.4e-06 28.1 0.0 8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 CBK21247.2 - 0.00014 21.4 0.0 0.0093 15.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CBK21247.2 - 0.0007 19.9 0.0 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBK21247.2 - 0.0035 16.4 0.0 0.0083 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 CBK21247.2 - 0.0046 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain APS_kinase PF01583.15 CBK21247.2 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.1 CBK21247.2 - 0.011 15.6 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBK21247.2 - 0.014 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) His_Phos_2 PF00328.17 CBK21247.2 - 0.027 13.8 0.1 0.35 10.1 0.0 2.5 2 1 0 3 3 3 0 Histidine phosphatase superfamily (branch 2) NTPase_1 PF03266.10 CBK21247.2 - 0.03 14.0 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CBK21247.2 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CBK21247.2 - 0.064 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CBK21247.2 - 0.12 12.0 0.1 0.41 10.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Methyltransf_32 PF13679.1 CBK21247.2 - 0.12 12.0 0.0 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.1 CBK21247.2 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPI_Ypi1 PF07491.6 CBK21248.2 - 4.4e-24 83.8 2.9 6e-24 83.4 2.0 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor MCM PF00493.18 CBK21249.2 - 3e-100 335.2 0.0 4e-100 334.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBK21249.2 - 0.0011 18.1 0.0 0.013 14.6 0.0 2.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBK21249.2 - 0.0039 16.9 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sars6 PF12133.3 CBK21249.2 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Ogr_Delta PF04606.7 CBK21249.2 - 0.044 13.4 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger DUF4413 PF14372.1 CBK21249.2 - 0.18 11.7 0.3 0.99 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Asp PF00026.18 CBK21250.2 - 3.2e-28 98.8 0.0 4.1e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 CBK21250.2 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal RNA_POL_M_15KD PF02150.11 CBK21251.2 - 1.1e-08 34.5 2.8 1.1e-08 34.5 2.0 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CBK21251.2 - 7.6e-08 31.8 3.1 7.6e-08 31.8 2.2 3.5 4 0 0 4 4 4 2 Transcription factor S-II (TFIIS) Rpr2 PF04032.11 CBK21251.2 - 0.017 14.9 3.3 0.017 14.9 2.3 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 CBK21251.2 - 0.029 14.1 1.7 0.029 14.1 1.2 2.8 2 2 0 2 2 2 0 Double zinc ribbon RecR PF02132.10 CBK21251.2 - 0.23 10.9 9.1 0.47 9.9 0.2 3.2 3 0 0 3 3 3 0 RecR protein RPA_interact_C PF14768.1 CBK21251.2 - 0.53 10.7 9.0 0.79 10.1 1.6 2.3 2 0 0 2 2 2 0 Replication protein A interacting C-terminal HSP70 PF00012.15 CBK21252.2 - 1.7e-57 194.7 0.1 2.5e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21252.2 - 2.2e-12 46.2 0.0 4e-07 28.9 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein PilM_2 PF11104.3 CBK21252.2 - 0.072 11.9 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; FtsA PF14450.1 CBK21252.2 - 0.18 11.6 2.4 11 5.8 0.1 3.4 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CBK21252.2 - 0.21 10.6 0.0 4.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 CBK21253.2 - 3.9e-45 153.8 0.1 5e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21253.2 - 1.5e-13 50.0 0.1 9.2e-10 37.6 0.0 3.7 2 1 0 2 2 2 2 MreB/Mbl protein StbA PF06406.6 CBK21253.2 - 3.6e-05 22.8 0.3 0.049 12.5 0.1 2.3 2 0 0 2 2 2 2 StbA protein DUF4379 PF14311.1 CBK21254.2 - 1.6e-17 63.0 13.4 2.3e-10 40.1 3.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4379) FANCL_C PF11793.3 CBK21254.2 - 0.0033 17.3 2.4 0.079 12.9 0.1 2.7 3 0 0 3 3 3 2 FANCL C-terminal domain Glyco_transf_49 PF13896.1 CBK21255.2 - 1.7e-16 60.2 0.0 1e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Tim54 PF11711.3 CBK21255.2 - 0.056 12.0 2.6 0.079 11.5 1.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FancD2 PF14631.1 CBK21255.2 - 1.5 5.7 5.0 2.2 5.2 3.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ribosomal_60s PF00428.14 CBK21255.2 - 3.8 7.9 15.7 7.3 7.0 10.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein UDP-g_GGTase PF06427.6 CBK21256.2 - 5.1e-30 104.3 0.0 1.9e-29 102.4 0.0 1.9 1 1 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CBK21256.2 - 9.5e-07 28.3 1.0 2.1e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 6PGD PF00393.14 CBK21257.2 - 2.6e-48 164.7 0.0 3.5e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBK21257.2 - 1.3e-25 90.1 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CBK21257.2 - 0.0045 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Peptidase_M14 PF00246.19 CBK21258.2 - 1.2e-24 87.4 0.0 1.6e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Proteasome PF00227.21 CBK21260.2 - 7.9e-46 155.7 0.4 1e-45 155.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK21260.2 - 3.4e-14 51.8 0.1 5.4e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DNA_pol_B_2 PF03175.8 CBK21261.2 - 1e-08 34.3 9.4 0.0013 17.5 0.2 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral bZIP_1 PF00170.16 CBK21262.2 - 1.2e-08 34.7 18.7 2.5e-08 33.7 13.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CBK21262.2 - 1e-07 31.6 18.1 1e-07 31.6 12.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CBK21262.2 - 0.00016 21.8 16.0 0.00021 21.5 10.5 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor Macoilin PF09726.4 CBK21262.2 - 0.0082 14.4 3.4 0.0091 14.3 2.4 1.0 1 0 0 1 1 1 1 Transmembrane protein Syntaxin PF00804.20 CBK21262.2 - 0.027 14.6 3.9 0.047 13.8 2.7 1.3 1 0 0 1 1 1 0 Syntaxin DUF2400 PF09674.5 CBK21262.2 - 0.12 12.0 0.9 0.16 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) NYD-SP28_assoc PF14775.1 CBK21262.2 - 0.14 11.8 3.3 0.29 10.8 2.3 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain Atg14 PF10186.4 CBK21262.2 - 1.1 8.1 13.8 1.5 7.7 9.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 CBK21262.2 - 1.3 8.0 6.2 1.8 7.5 4.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CENP-H PF05837.7 CBK21262.2 - 1.6 8.9 11.4 0.04 14.0 2.8 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SPT6_acidic PF14632.1 CBK21262.2 - 2.8 8.1 9.5 5.3 7.2 6.6 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DivIC PF04977.10 CBK21262.2 - 4.9 6.7 8.4 2.1 7.8 3.9 1.9 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_3 PF13758.1 CBK21263.2 - 0.0065 16.2 0.6 0.021 14.6 0.4 1.8 2 0 0 2 2 2 1 Prefoldin subunit RICH PF05062.7 CBK21263.2 - 0.083 13.0 0.3 0.87 9.7 0.4 2.2 2 0 0 2 2 2 0 RICH domain ETC_C1_NDUFA5 PF04716.9 CBK21264.2 - 5.8e-20 70.5 0.5 1e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2247 PF10004.4 CBK21264.2 - 0.13 11.9 0.6 0.18 11.4 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) He_PIG PF05345.7 CBK21265.2 - 5.7e-06 26.2 0.4 0.017 15.1 1.1 2.6 2 0 0 2 2 2 2 Putative Ig domain RNA_pol_L_2 PF13656.1 CBK21266.2 - 2.7e-14 52.3 0.0 4.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBK21266.2 - 0.024 13.7 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 CBK21266.2 - 0.061 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Tn916-Xis PF09035.5 CBK21266.2 - 0.13 12.3 0.1 0.35 11.0 0.0 1.8 2 1 1 3 3 3 0 Excisionase from transposon Tn916 PTPLA PF04387.9 CBK21267.2 - 7.4e-54 181.5 13.0 7.4e-54 181.5 9.0 1.3 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Actin PF00022.14 CBK21268.2 - 3.8e-23 81.5 0.0 4.5e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Actin Copine PF07002.11 CBK21269.2 - 2.7e-45 153.7 0.0 4.2e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 CBK21269.2 - 2.4e-11 43.3 0.1 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.4 CBK21269.2 - 4.5e-08 33.1 0.0 8.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 CBK21269.2 - 0.043 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain GCV_H PF01597.14 CBK21270.2 - 1.5e-42 144.1 0.0 1.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Pentapeptide_4 PF13599.1 CBK21270.2 - 0.03 14.1 1.6 0.049 13.4 1.1 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Biotin_lipoyl PF00364.17 CBK21270.2 - 0.053 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme Ribosomal_S8e PF01201.17 CBK21271.2 - 2.8e-32 111.6 0.1 3.3e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_4 PF14570.1 CBK21272.2 - 1.7e-15 56.2 14.5 1.7e-15 56.2 10.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CBK21272.2 - 9.7e-05 21.9 14.4 0.00025 20.6 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CBK21272.2 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CBK21272.2 - 0.0027 17.5 17.6 0.0082 15.9 12.2 1.9 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CBK21272.2 - 0.011 14.9 8.9 0.022 13.9 6.2 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger RRM_6 PF14259.1 CBK21272.2 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21272.2 - 0.017 14.9 0.1 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad50_zn_hook PF04423.9 CBK21272.2 - 0.039 13.4 0.5 0.039 13.4 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_2 PF13923.1 CBK21272.2 - 0.94 9.5 14.3 2.7 8.0 9.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 CBK21272.2 - 1 9.2 14.7 2.4 8.0 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rad51 PF08423.6 CBK21274.2 - 2e-125 416.9 0.3 2.4e-125 416.5 0.2 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK21274.2 - 4.7e-15 55.5 0.1 6.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK21274.2 - 1.3e-11 44.2 0.3 1.6e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBK21274.2 - 1.2e-07 31.0 0.2 2.5e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBK21274.2 - 0.00023 20.1 0.8 0.0016 17.4 0.0 2.2 2 1 1 3 3 3 1 DnaB-like helicase C terminal domain AAA_24 PF13479.1 CBK21274.2 - 0.0015 18.1 0.0 0.0047 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK21274.2 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 CBK21274.2 - 0.11 12.7 0.1 0.48 10.6 0.0 2.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain Actin PF00022.14 CBK21275.2 - 1.4e-86 290.3 0.0 1.6e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK21275.2 - 0.0036 15.9 0.0 0.32 9.5 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein XLF PF09302.6 CBK21276.2 - 0.063 13.0 0.1 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 XLF (XRCC4-like factor) HCaRG PF07258.9 CBK21277.2 - 6.1e-10 38.9 0.2 7.4e-10 38.6 0.1 1.0 1 0 0 1 1 1 1 HCaRG protein SAICAR_synt PF01259.13 CBK21278.2 - 4e-72 242.3 0.0 5.4e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.15 CBK21278.2 - 2.1e-38 130.9 0.0 3.4e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 AIR carboxylase Ribosomal_L5_C PF00673.16 CBK21280.2 - 2.8e-22 78.2 0.0 4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBK21280.2 - 2.7e-18 65.4 0.6 1.4e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Rotamase PF00639.16 CBK21281.2 - 4.4e-20 72.2 0.0 6.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBK21281.2 - 3e-15 56.5 0.0 4.1e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBK21281.2 - 0.00012 22.6 0.0 0.00041 20.9 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain NADH_4Fe-4S PF10589.4 CBK21281.2 - 0.31 10.2 4.0 0.31 10.2 1.8 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Ribosomal_60s PF00428.14 CBK21283.2 - 3.7e-24 84.9 16.4 4.3e-24 84.7 11.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF867 PF05908.6 CBK21283.2 - 0.055 12.5 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Myc_N PF01056.13 CBK21283.2 - 0.31 10.1 3.3 0.29 10.2 2.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 CBK21283.2 - 5.3 6.6 8.4 6.8 6.2 5.7 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_Rpb5_C PF01191.14 CBK21284.2 - 1.5e-25 88.5 0.0 3.1e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CBK21284.2 - 3e-07 30.7 0.0 4.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CBK21284.2 - 0.051 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Pkinase PF00069.20 CBK21285.2 - 1e-22 80.5 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21285.2 - 6.6e-11 41.7 0.0 2.1e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK21285.2 - 0.022 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK21285.2 - 0.066 12.1 0.1 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Cadherin_C PF01049.12 CBK21285.2 - 0.072 13.1 0.4 0.69 9.9 0.0 2.5 3 0 0 3 3 3 0 Cadherin cytoplasmic region Seadorna_VP7 PF07387.6 CBK21285.2 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_N PF00134.18 CBK21286.2 - 8.5e-33 112.6 1.2 1.5e-32 111.8 0.9 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mito_fiss_reg PF05308.6 CBK21287.2 - 0.061 12.6 1.5 0.07 12.4 1.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 CBK21287.2 - 5.3 6.2 6.1 7.7 5.7 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2417 PF10329.4 CBK21288.2 - 0.015 14.6 0.2 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Hist_deacetyl PF00850.14 CBK21289.2 - 2.8e-77 260.0 0.0 4e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MIF4G PF02854.14 CBK21290.2 - 1.3e-27 96.5 1.3 1.3e-27 96.5 0.9 2.3 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBK21290.2 - 1.6e-16 60.0 1.2 2.7e-15 56.0 0.2 2.6 2 1 0 2 2 2 1 MA3 domain PBP1_TM PF14812.1 CBK21290.2 - 0.11 12.8 11.6 0.21 11.8 8.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 CBK21290.2 - 0.14 11.3 12.1 0.2 10.7 8.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.7 CBK21290.2 - 0.23 11.1 13.0 0.4 10.3 9.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 CBK21290.2 - 0.31 10.7 4.7 0.59 9.8 3.2 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 CBK21290.2 - 0.34 8.8 10.1 0.49 8.3 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 CBK21290.2 - 0.39 10.2 16.7 0.71 9.3 11.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF506 PF04720.7 CBK21290.2 - 0.5 9.9 3.9 0.99 8.9 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Vfa1 PF08432.5 CBK21290.2 - 0.74 9.8 8.0 1.3 8.9 5.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.6 CBK21290.2 - 1.2 8.7 8.7 2 8.0 6.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2722 PF10846.3 CBK21290.2 - 8.4 5.3 6.7 12 4.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2890 PF11081.3 CBK21290.2 - 8.5 6.3 13.4 15 5.5 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 CBK21290.2 - 8.9 4.9 25.0 12 4.4 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sua5_yciO_yrdC PF01300.13 CBK21291.2 - 2.7e-49 166.8 0.0 4.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CBK21291.2 - 5.3e-14 52.3 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding V-ATPase_H_C PF11698.3 CBK21292.2 - 0.053 13.4 0.1 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 V-ATPase subunit H HSP20 PF00011.16 CBK21293.2 - 1.4e-27 95.4 3.2 1.7e-27 95.2 2.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF104 PF01954.11 CBK21293.2 - 0.08 12.9 2.2 0.52 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK21293.2 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Radical_SAM PF04055.16 CBK21294.2 - 6.3e-25 88.2 0.4 2.2e-24 86.4 0.2 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 CBK21294.2 - 0.11 12.5 5.0 0.26 11.3 3.5 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.1 CBK21294.2 - 0.36 10.9 5.4 0.96 9.5 3.7 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain IBN_N PF03810.14 CBK21296.2 - 1.4e-05 24.8 0.1 4.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CBK21296.2 - 3.9e-05 22.1 0.1 9.2e-05 20.9 0.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region ParcG PF10274.4 CBK21296.2 - 0.094 12.6 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein SAPS PF04499.10 CBK21296.2 - 0.14 10.7 0.0 0.14 10.7 0.0 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Vps35 PF03635.12 CBK21297.2 - 1.3e-12 46.7 0.2 1.3e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Hormone_recep PF00104.25 CBK21297.2 - 0.064 12.3 0.1 0.068 12.2 0.1 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Vps35 PF03635.12 CBK21298.2 - 1.3e-73 248.5 8.6 1.4e-71 241.7 6.0 2.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RabGAP-TBC PF00566.13 CBK21299.2 - 6.5e-21 74.8 0.0 7.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MORN PF02493.15 CBK21300.2 - 2.5e-05 23.7 9.9 0.016 14.9 0.6 3.1 3 0 0 3 3 3 2 MORN repeat MORN_2 PF07661.8 CBK21300.2 - 0.073 13.1 3.7 25 5.3 0.0 3.8 3 0 0 3 3 3 0 MORN repeat variant MORN PF02493.15 CBK21301.2 - 0.0029 17.2 28.8 1.4 8.7 0.1 8.4 7 0 0 7 7 7 4 MORN repeat Slu7 PF11708.3 CBK21304.2 - 1.9e-42 145.7 4.5 3.2e-42 144.9 3.2 1.4 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor DUF2031 PF09592.5 CBK21304.2 - 0.056 12.5 0.3 0.073 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) AKAP2_C PF15304.1 CBK21304.2 - 0.069 12.7 5.8 0.085 12.4 4.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF2235 PF09994.4 CBK21304.2 - 0.23 10.8 0.2 0.23 10.8 0.1 1.7 1 1 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) HORMA PF02301.13 CBK21305.2 - 5.4e-40 137.1 1.0 6e-40 136.9 0.7 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 CBK21305.2 - 0.0062 15.9 0.2 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Autophagy-related protein 13 Neur_chan_LBD PF02931.18 CBK21305.2 - 0.018 14.1 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain PcfJ PF14284.1 CBK21305.2 - 0.082 12.3 0.1 0.13 11.7 0.1 1.4 1 1 0 1 1 1 0 PcfJ-like protein SRP40_C PF05022.7 CBK21306.2 - 1.3e-22 80.0 2.2 4.6e-22 78.2 1.5 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain B56 PF01603.15 CBK21307.2 - 7.8e-24 84.0 2.7 8.8e-24 83.8 1.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.15 CBK21308.2 - 2e-13 49.7 0.0 2.3e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Asparaginase PF00710.15 CBK21309.2 - 2.4e-71 240.1 0.0 2.9e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Radical_SAM PF04055.16 CBK21310.2 - 1.3e-31 110.0 0.2 2.8e-31 108.9 0.2 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 CBK21310.2 - 3.4e-20 71.7 0.6 6.2e-20 70.8 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 CBK21310.2 - 0.00022 20.9 0.0 0.00075 19.2 0.0 1.9 1 1 0 1 1 1 1 TRAM domain TRAM_LAG1_CLN8 PF03798.11 CBK21311.2 - 5.6e-22 78.2 28.5 5.6e-22 78.2 19.7 2.6 1 1 1 2 2 2 1 TLC domain TRAM1 PF08390.6 CBK21311.2 - 1.1e-07 31.2 0.2 1.1e-07 31.2 0.1 2.5 2 0 0 2 2 2 1 TRAM1-like protein WD40 PF00400.27 CBK21312.2 - 9.5e-09 34.8 1.1 0.002 17.9 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 CBK21312.2 - 1.3e-06 26.5 0.0 3.2e-05 21.9 0.1 1.9 1 1 1 2 2 2 2 IKI3 family eIF2A PF08662.6 CBK21312.2 - 2e-05 24.4 0.3 2.5e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 CBK21312.2 - 0.053 13.2 1.7 0.74 9.5 0.9 2.7 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term VRR_NUC PF08774.6 CBK21312.2 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 VRR-NUC domain Apc4_WD40 PF12894.2 CBK21312.2 - 0.55 9.7 2.7 18 4.8 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NARP1 PF12569.3 CBK21313.2 - 2.7e-93 313.4 0.4 2.2e-88 297.2 0.0 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 CBK21313.2 - 1.6e-08 34.7 6.8 0.0034 17.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21313.2 - 5e-06 26.6 12.9 0.71 10.6 0.6 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK21313.2 - 5.1e-06 26.0 9.4 0.32 11.0 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBK21313.2 - 4.5e-05 23.0 12.7 0.073 12.7 0.2 5.0 5 1 2 7 7 7 3 TPR repeat TPR_12 PF13424.1 CBK21313.2 - 8.8e-05 22.3 1.7 0.097 12.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21313.2 - 9.6e-05 21.8 2.7 0.2 11.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21313.2 - 0.00074 20.1 18.8 0.29 11.8 0.2 7.1 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBK21313.2 - 0.002 17.7 4.5 0.48 10.3 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Clathrin PF00637.15 CBK21314.2 - 2.5e-18 66.0 4.6 8.8e-17 61.0 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CBK21314.2 - 6.2e-09 36.0 4.2 4.6e-08 33.2 0.3 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 CBK21314.2 - 0.0011 19.0 1.1 0.004 17.2 0.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBK21314.2 - 0.0023 17.7 8.6 0.025 14.4 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain TPR_15 PF13429.1 CBK21314.2 - 0.028 13.4 0.3 0.64 9.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 CBK21314.2 - 1.4 8.9 8.4 8.1 6.5 5.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 CBK21314.2 - 4.3 7.1 7.8 0.5 10.1 2.3 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DHC_N1 PF08385.7 CBK21315.2 - 0.016 13.6 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Sfi1 PF08457.5 CBK21315.2 - 0.052 11.9 0.0 0.06 11.7 0.0 1.0 1 0 0 1 1 1 0 Sfi1 spindle body protein Vps52 PF04129.7 CBK21316.2 - 3.3e-27 95.2 1.2 4e-27 94.9 0.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family NA37 PF04245.8 CBK21316.2 - 0.071 12.4 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Band_7 PF01145.20 CBK21317.2 - 9.5e-25 87.5 8.9 6.6e-24 84.7 6.2 2.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family DivIVA PF05103.8 CBK21317.2 - 0.0039 17.2 4.8 0.0073 16.3 3.3 1.4 1 0 0 1 1 1 1 DivIVA protein SUKH_5 PF14567.1 CBK21317.2 - 0.082 12.3 0.2 0.6 9.5 0.0 2.2 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall Caudo_TAP PF02413.12 CBK21317.2 - 0.24 11.5 4.5 1.7 8.8 3.1 2.1 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein V-ATPase_G PF03179.10 CBK21317.2 - 0.94 9.8 11.8 0.11 12.8 2.7 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CBK21317.2 - 1.1 9.0 10.0 0.32 10.8 3.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) He_PIG PF05345.7 CBK21318.2 - 1.6e-05 24.7 0.9 4.4e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Putative Ig domain DUF912 PF06024.7 CBK21318.2 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ODV-E18 PF10717.4 CBK21318.2 - 0.02 14.2 0.1 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.1 CBK21318.2 - 0.077 13.1 0.4 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CD34_antigen PF06365.7 CBK21318.2 - 0.098 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3844 PF12955.2 CBK21318.2 - 0.11 12.6 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) TMEM154 PF15102.1 CBK21318.2 - 0.11 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SP_C-Propep PF08999.5 CBK21318.2 - 0.13 11.7 2.9 0.3 10.6 2.0 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.1 CBK21318.2 - 0.24 11.8 3.4 0.42 11.0 2.4 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4389 PF14333.1 CBK21318.2 - 0.24 11.1 2.2 0.47 10.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF1180 PF06679.7 CBK21318.2 - 1.5 8.6 4.1 2.5 7.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pyr_redox_2 PF07992.9 CBK21319.2 - 5.3e-34 117.8 0.0 4.7e-33 114.7 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBK21319.2 - 1.1e-17 64.2 4.0 1.6e-17 63.6 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBK21319.2 - 1.3e-11 44.4 0.4 4.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 CBK21319.2 - 2.3e-11 44.1 0.0 1.6e-06 28.3 0.0 3.2 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBK21319.2 - 1.5e-08 33.9 3.4 0.0012 17.8 0.0 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Rhodanese PF00581.15 CBK21319.2 - 4.3e-07 30.2 0.0 9.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain NAD_binding_8 PF13450.1 CBK21319.2 - 7.1e-07 29.1 1.4 0.031 14.3 0.0 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBK21319.2 - 1.1e-05 24.1 2.3 0.17 10.2 0.0 3.9 3 1 1 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.7 CBK21319.2 - 5.8e-05 22.1 1.1 0.75 8.6 0.1 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein DUF1188 PF06690.6 CBK21319.2 - 0.00019 20.6 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.13 CBK21319.2 - 0.00051 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 CBK21319.2 - 0.00086 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CBK21319.2 - 0.0048 16.6 1.0 7.8 6.2 0.1 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CBK21319.2 - 0.0064 15.3 1.1 1.9 7.2 0.1 3.3 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 CBK21319.2 - 0.0093 16.2 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 CBK21319.2 - 0.027 14.4 0.3 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Cyclin_N PF00134.18 CBK21320.2 - 2.5e-07 30.3 2.9 1.9e-06 27.4 0.1 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain MutS_V PF00488.16 CBK21321.2 - 7.2e-82 274.3 0.0 1.1e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBK21321.2 - 2.4e-33 115.6 0.2 3.7e-33 115.0 0.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 CBK21321.2 - 2.9e-08 33.7 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_25 PF13481.1 CBK21321.2 - 0.12 11.8 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CBK21322.2 - 1.6e-30 104.5 0.0 1e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21322.2 - 1.8e-16 59.8 0.0 7.3e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21322.2 - 3.4e-13 49.2 0.0 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK21322.2 - 0.0027 17.4 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 Ribosomal_L29e PF01779.12 CBK21323.2 - 1.7e-17 62.9 8.4 1.7e-17 62.9 5.8 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family Radical_SAM PF04055.16 CBK21324.2 - 2.3e-09 37.6 1.4 5.5e-09 36.4 1.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 CBK21324.2 - 1.7e-07 31.2 0.2 4.4e-07 29.9 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 CBK21324.2 - 3.8e-07 30.2 0.5 9.9e-07 28.9 0.4 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain GTP_EFTU PF00009.22 CBK21325.2 - 4.1e-30 104.6 3.0 4.1e-30 104.6 2.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBK21325.2 - 5.2e-12 45.6 1.0 1.5e-11 44.1 0.1 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CBK21325.2 - 3.3e-08 33.5 0.2 8.8e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBK21325.2 - 2.5e-06 27.9 0.1 5.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CBK21325.2 - 2.4e-05 23.8 0.1 9.7e-05 21.8 0.2 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CBK21325.2 - 4e-05 22.8 0.0 8.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CBK21325.2 - 0.0014 18.4 0.9 0.11 12.3 0.0 2.9 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 CBK21325.2 - 0.0023 17.1 0.0 0.0057 15.9 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 CBK21325.2 - 0.0038 16.5 0.1 0.0081 15.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Flg_hook PF02120.11 CBK21325.2 - 0.022 14.4 0.1 0.066 12.8 0.1 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Ras PF00071.17 CBK21325.2 - 0.037 13.4 0.1 0.098 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras family GTP_EFTU_D2 PF03144.20 CBK21325.2 - 0.22 11.6 3.0 0.23 11.6 0.1 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBK21326.2 - 0.0067 16.0 0.1 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DUF4362 PF14275.1 CBK21326.2 - 0.13 12.3 0.3 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) FYVE PF01363.16 CBK21327.2 - 0.0039 17.0 15.9 0.0076 16.1 11.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger Med22 PF06179.7 CBK21327.2 - 0.064 13.2 4.0 0.41 10.6 0.7 2.9 2 1 1 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex ADIP PF11559.3 CBK21327.2 - 0.075 12.9 14.5 0.039 13.8 8.4 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 CBK21327.2 - 0.076 13.1 4.3 0.29 11.2 1.5 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sigma70_ner PF04546.8 CBK21327.2 - 0.24 11.0 8.8 0.38 10.3 6.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TBPIP PF07106.8 CBK21327.2 - 0.42 10.1 14.4 0.085 12.3 2.3 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 CBK21327.2 - 1.2 9.2 10.4 0.46 10.6 1.3 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CBK21327.2 - 1.3 6.8 5.7 1.6 6.5 3.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 CBK21327.2 - 1.4 7.2 11.4 0.34 9.3 5.8 1.4 2 0 0 2 2 2 0 AAA domain SlyX PF04102.7 CBK21327.2 - 1.6 9.1 7.1 1.1 9.6 1.1 3.1 1 1 1 2 2 2 0 SlyX Asp PF00026.18 CBK21328.2 - 4e-06 26.3 0.0 4.1e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Thioredoxin PF00085.15 CBK21329.2 - 2.9e-21 75.0 0.0 4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CBK21329.2 - 5.8e-06 25.8 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBK21329.2 - 8.9e-05 22.5 0.1 0.016 15.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBK21329.2 - 0.0081 16.1 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBK21329.2 - 0.014 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 CBK21329.2 - 0.026 14.7 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DUF953 PF06110.6 CBK21329.2 - 0.029 13.8 0.5 0.12 11.8 0.3 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) HSP20 PF00011.16 CBK21331.2 - 1.4e-27 95.4 3.2 1.7e-27 95.2 2.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF104 PF01954.11 CBK21331.2 - 0.08 12.9 2.2 0.52 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK21331.2 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF563 PF04577.9 CBK21332.2 - 7.3e-18 65.2 1.3 1.2e-17 64.5 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) HSP20 PF00011.16 CBK21333.2 - 1.4e-27 95.4 3.2 1.7e-27 95.2 2.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF104 PF01954.11 CBK21333.2 - 0.08 12.9 2.2 0.52 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK21333.2 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Snf7 PF03357.16 CBK21334.2 - 0.0039 16.6 6.1 0.0056 16.0 4.3 1.2 1 0 0 1 1 1 1 Snf7 Ino80_Iec3 PF14612.1 CBK21334.2 - 0.013 15.5 0.3 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling BNIP2 PF12496.3 CBK21334.2 - 0.026 14.7 2.2 0.03 14.4 1.5 1.0 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Nuc_sug_transp PF04142.10 CBK21335.2 - 8.1e-54 182.3 17.5 8.1e-54 182.3 12.1 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CBK21335.2 - 6.4e-11 42.3 27.6 1.9e-09 37.6 5.1 3.0 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBK21335.2 - 7.6e-10 38.6 27.8 8.8e-06 25.4 7.9 3.6 2 2 1 3 3 3 3 Triose-phosphate Transporter family UAA PF08449.6 CBK21335.2 - 7.6e-09 34.9 34.8 5.3e-06 25.5 5.3 3.2 2 1 1 3 3 3 3 UAA transporter family EmrE PF13536.1 CBK21335.2 - 1.2e-07 31.8 23.4 3e-05 24.1 2.6 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF1195 PF06708.6 CBK21335.2 - 0.059 12.7 0.6 0.15 11.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) CBFB_NFYA PF02045.10 CBK21336.2 - 1.7e-23 82.9 5.4 2.2e-23 82.5 3.7 1.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF2040 PF09745.4 CBK21336.2 - 0.038 13.8 0.8 0.042 13.6 0.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) DnaJ PF00226.26 CBK21337.2 - 6.8e-17 60.9 1.1 6.8e-17 60.9 0.7 2.1 2 0 0 2 2 2 1 DnaJ domain HI0933_like PF03486.9 CBK21338.2 - 0.57 8.5 3.0 0.78 8.1 2.0 1.3 1 0 0 1 1 1 0 HI0933-like protein SLY PF12485.3 CBK21338.2 - 1.1 9.5 9.6 2 8.6 6.7 1.5 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF2939 PF11159.3 CBK21338.2 - 1.2 9.3 11.6 1.3e+03 -0.5 7.2 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) DUF445 PF04286.7 CBK21338.2 - 2.2 7.7 11.9 2.2 7.6 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4468 PF14730.1 CBK21338.2 - 2.4 7.8 10.5 1.6e+03 -1.2 7.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Spore_III_AF PF09581.5 CBK21338.2 - 9.7 6.0 7.4 34 4.2 5.1 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) APG6 PF04111.7 CBK21339.2 - 0.009 15.0 3.4 0.01 14.9 2.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 ExbD PF02472.11 CBK21339.2 - 0.057 13.4 0.7 0.088 12.7 0.5 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR RabGAP-TBC PF00566.13 CBK21340.2 - 1.6e-15 57.1 3.7 3.2e-15 56.2 2.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gag_p24 PF00607.15 CBK21341.2 - 0.16 11.4 1.8 0.17 11.4 0.4 1.6 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) MFS_1 PF07690.11 CBK21342.2 - 1.3e-06 27.3 10.1 3.2e-06 26.0 5.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK21342.2 - 0.05 12.1 4.0 0.02 13.4 0.8 1.6 1 1 1 2 2 2 0 Sugar (and other) transporter PrkA PF06798.7 CBK21343.2 - 0.041 13.1 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain FliE PF02049.13 CBK21343.2 - 0.098 12.6 0.1 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Exo_endo_phos PF03372.18 CBK21344.2 - 3e-10 40.4 0.0 6.1e-10 39.4 0.0 1.5 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family UDPG_MGDP_dh_N PF03721.9 CBK21345.2 - 6.4e-49 165.8 0.1 1.5e-48 164.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 CBK21345.2 - 3.8e-25 87.9 0.0 7.1e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 CBK21345.2 - 4.2e-22 78.2 0.4 3.9e-21 75.1 0.2 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.10 CBK21345.2 - 6.1e-06 26.1 0.1 3.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 CBK21345.2 - 0.00099 18.2 0.2 0.19 10.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBK21345.2 - 0.0012 18.5 0.9 0.0082 15.8 0.0 2.6 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CBK21345.2 - 0.0047 16.6 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 CBK21345.2 - 0.052 12.4 1.4 2.3 7.0 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBK21345.2 - 0.29 11.5 3.4 0.93 9.9 1.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cation_efflux PF01545.16 CBK21346.2 - 3.4e-45 154.3 0.1 4.4e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Galactosyl_T PF01762.16 CBK21347.2 - 3.2e-33 114.9 0.0 4.7e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.16 CBK21348.2 - 1.8e-31 109.2 0.0 2.8e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.16 CBK21349.2 - 2e-33 115.6 0.0 2.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Trypan_PARP PF05887.6 CBK21351.2 - 0.023 14.5 12.7 0.033 14.0 8.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) hSac2 PF12456.3 CBK21351.2 - 0.096 12.0 0.6 2.8 7.3 0.0 3.0 1 1 3 4 4 4 0 Inositol phosphatase DEC-1_N PF04625.8 CBK21351.2 - 0.16 10.6 21.4 0.22 10.1 14.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LRR_8 PF13855.1 CBK21351.2 - 0.18 11.5 2.4 7.8 6.3 0.0 3.1 2 1 1 3 3 3 0 Leucine rich repeat PLRV_ORF5 PF01690.12 CBK21351.2 - 0.43 9.6 37.1 0.051 12.7 9.9 2.1 1 1 1 2 2 2 0 Potato leaf roll virus readthrough protein DUF2360 PF10152.4 CBK21351.2 - 0.7 10.1 3.0 1 9.6 2.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ArfGap PF01412.13 CBK21352.2 - 2.7e-35 120.6 0.0 3.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.12 CBK21352.2 - 2.1 8.1 6.9 0.77 9.5 0.1 2.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-H2C2_2 PF13465.1 CBK21353.2 - 1e-18 66.5 34.0 2.5e-09 36.9 0.5 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBK21353.2 - 6.1e-18 63.9 32.3 0.00019 21.5 2.4 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK21353.2 - 8.3e-14 50.8 29.7 6.3e-05 23.0 2.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 CBK21353.2 - 2.1e-07 30.9 6.3 0.32 11.2 0.0 4.7 4 1 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBK21353.2 - 0.00028 20.9 10.2 0.11 12.7 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Toxin_8 PF07365.7 CBK21353.2 - 2.1 8.3 7.7 0.13 12.2 0.9 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor zf-H2C2_5 PF13909.1 CBK21353.2 - 5.6 7.3 17.3 3 8.2 1.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain AhpC-TSA PF00578.16 CBK21354.2 - 1.7e-35 121.4 0.0 2.3e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK21354.2 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK21354.2 - 2.2e-12 46.4 0.0 4.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LMWPc PF01451.16 CBK21356.2 - 2.1e-24 86.4 0.0 2.3e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyco_transf_49 PF13896.1 CBK21357.2 - 2.4e-18 66.3 0.1 2.3e-15 56.5 0.0 3.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK21357.2 - 0.0042 16.2 0.1 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Sec63 PF02889.11 CBK21358.2 - 6e-160 531.6 0.0 3.2e-94 315.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBK21358.2 - 8.1e-45 152.3 0.4 9.8e-26 90.2 0.1 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 CBK21358.2 - 4.2e-14 52.8 0.0 6.9e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBK21358.2 - 2.5e-09 36.8 0.0 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBK21358.2 - 1.3e-06 27.4 0.1 3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CBK21358.2 - 0.01 15.9 0.1 0.1 12.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0158 PF03682.8 CBK21358.2 - 0.018 14.6 0.7 0.053 13.1 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) AAA_19 PF13245.1 CBK21358.2 - 0.022 14.4 0.8 0.15 11.8 0.0 3.0 4 0 0 4 4 4 0 Part of AAA domain NAD_binding_2 PF03446.10 CBK21362.2 - 3e-26 92.2 0.2 4e-26 91.7 0.2 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBK21362.2 - 4.8e-10 39.5 0.5 8.6e-10 38.7 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CBF PF03914.12 CBK21363.2 - 7.3e-32 110.0 33.6 6.6e-30 103.7 21.5 4.1 2 2 0 2 2 2 1 CBF/Mak21 family BUD22 PF09073.5 CBK21363.2 - 0.00018 20.7 55.0 0.00018 20.7 38.1 3.5 3 0 0 3 3 3 1 BUD22 eIF-3c_N PF05470.7 CBK21363.2 - 0.0042 15.2 0.1 0.0042 15.2 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hid1 PF12722.2 CBK21363.2 - 6.9 4.2 32.7 0.0083 13.8 14.5 1.8 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF3630 PF12305.3 CBK21364.2 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3630) DUF563 PF04577.9 CBK21365.2 - 2.4e-18 66.8 0.6 5.9e-18 65.5 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) NAD_binding_2 PF03446.10 CBK21366.2 - 5.9e-46 156.2 0.2 8.7e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBK21366.2 - 7.2e-34 116.4 0.1 1.3e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CBK21366.2 - 2.3e-06 27.7 0.0 4.9e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CBK21366.2 - 0.031 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 CBK21368.2 - 1.9e-23 82.2 3.4 3.3e-23 81.5 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBK21368.2 - 2.4e-08 33.5 0.0 3.9e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBK21368.2 - 0.00082 20.2 0.0 0.0013 19.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CBK21368.2 - 0.097 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LMBR1 PF04791.11 CBK21369.2 - 0.00018 20.2 1.5 0.00025 19.7 1.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein CENP-F_leu_zip PF10473.4 CBK21369.2 - 0.00033 20.5 14.6 0.00054 19.8 10.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.11 CBK21369.2 - 0.055 13.2 22.1 0.17 11.6 10.3 2.4 1 1 1 2 2 2 0 Hr1 repeat APG6 PF04111.7 CBK21369.2 - 0.12 11.4 13.2 0.18 10.8 9.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Apolipoprotein PF01442.13 CBK21369.2 - 0.17 11.3 10.4 1.6 8.1 7.2 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.10 CBK21369.2 - 0.19 10.8 5.1 0.31 10.1 3.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ctr PF04145.10 CBK21369.2 - 0.31 11.0 4.5 0.54 10.3 0.8 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF883 PF05957.8 CBK21369.2 - 0.76 10.2 7.9 0.97 9.8 0.5 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) DUF342 PF03961.8 CBK21369.2 - 0.88 7.9 10.8 1.2 7.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 CBK21369.2 - 1.9 8.4 14.3 3.8 7.4 8.9 2.0 1 1 0 1 1 1 0 FlxA-like protein AAA_13 PF13166.1 CBK21369.2 - 2.3 6.5 15.5 4.2 5.6 10.8 1.3 1 0 0 1 1 1 0 AAA domain DUF2968 PF11180.3 CBK21369.2 - 2.6 7.3 12.0 1.1 8.5 4.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF4140 PF13600.1 CBK21369.2 - 5.4 7.5 11.2 11 6.5 2.4 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF607 PF04678.8 CBK21369.2 - 8.8 6.2 9.0 0.85 9.5 2.3 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF607 MgsA_C PF12002.3 CBK21370.2 - 2.1e-39 134.8 0.0 3.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CBK21370.2 - 9e-14 51.8 0.0 1.9e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBK21370.2 - 1.1e-09 37.6 0.0 4.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBK21370.2 - 2.7e-06 27.1 0.0 2.2e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBK21370.2 - 4.4e-06 26.2 0.0 0.0048 16.4 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CBK21370.2 - 6.7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBK21370.2 - 1.6e-05 24.9 0.0 7.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 CBK21370.2 - 0.00011 21.0 0.2 0.00064 18.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CBK21370.2 - 0.00056 19.9 1.1 0.055 13.4 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBK21370.2 - 0.0013 18.8 0.6 0.11 12.6 0.5 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK21370.2 - 0.0046 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 CBK21370.2 - 0.0059 17.4 2.3 0.0068 17.2 0.0 2.3 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBK21370.2 - 0.006 15.7 0.1 3.2 6.8 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CBK21370.2 - 0.0061 16.8 0.4 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CBK21370.2 - 0.019 15.2 0.9 0.056 13.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 CBK21370.2 - 0.049 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBK21370.2 - 0.069 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 CBK21370.2 - 0.16 11.4 0.0 0.37 10.2 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 CBK21370.2 - 0.22 11.0 0.5 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 CBK21370.2 - 1.2 9.3 0.0 1.2 9.3 0.0 2.4 2 1 0 2 2 1 0 AAA domain ADH_N PF08240.7 CBK21371.2 - 2.9e-09 36.6 0.0 3.8e-08 33.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBK21371.2 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 CBK21372.2 - 1.4e-63 214.5 0.0 1.8e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21372.2 - 4.1e-30 104.7 0.0 5.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21372.2 - 0.0038 16.2 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK21372.2 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK21372.2 - 0.026 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med14 PF08638.6 CBK21375.2 - 4.7e-13 48.8 0.0 1.3e-12 47.3 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit MED14 CBFD_NFYB_HMF PF00808.18 CBK21376.2 - 7.9e-06 25.8 0.2 2.6e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCT PF06203.9 CBK21377.2 - 7e-05 22.3 2.6 0.00012 21.6 1.8 1.4 1 0 0 1 1 1 1 CCT motif Oxysterol_BP PF01237.13 CBK21378.2 - 1.6e-29 102.5 0.0 2.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein MyTH4 PF00784.12 CBK21379.2 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain FERM_M PF00373.13 CBK21379.2 - 2.8e-10 40.4 0.0 5.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 FERM central domain RA PF00788.18 CBK21379.2 - 0.0022 18.4 0.0 1.6 9.2 0.0 3.4 2 1 1 3 3 3 2 Ras association (RalGDS/AF-6) domain Peptidase_S24 PF00717.18 CBK21380.2 - 1.1e-07 31.4 0.0 2.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CBK21380.2 - 0.0002 20.8 0.0 0.21 11.1 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 AHSA1 PF08327.6 CBK21381.2 - 2.5e-10 40.5 0.0 2.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RNA_pol_Rpb1_5 PF04998.12 CBK21382.2 - 2.8e-91 305.6 0.0 3.4e-90 302.0 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBK21382.2 - 4.6e-56 189.3 0.0 1.3e-55 187.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBK21382.2 - 1.9e-34 118.6 0.0 4.7e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBK21382.2 - 2.4e-18 65.8 0.0 2.4e-18 65.8 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 CBK21382.2 - 3.9 5.2 42.1 0.58 8.0 21.0 2.2 2 0 0 2 2 2 0 Nop14-like family RNA_pol_Rpb1_1 PF04997.7 CBK21383.2 - 1.8e-24 86.6 0.6 2.1e-24 86.4 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNase_PH PF01138.16 CBK21384.2 - 1.6e-23 83.4 0.0 2.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBK21384.2 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MORN_2 PF07661.8 CBK21385.2 - 1.6e-09 36.7 10.8 0.29 11.2 0.1 8.6 9 0 0 9 9 9 3 MORN repeat variant MORN PF02493.15 CBK21385.2 - 0.16 11.7 10.1 1.1 9.1 0.5 5.2 5 0 0 5 5 5 0 MORN repeat HSP70 PF00012.15 CBK21386.2 - 6.5e-09 34.2 0.0 1.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein Snf7 PF03357.16 CBK21387.2 - 9.3e-07 28.3 6.2 1.2e-06 27.9 4.2 1.3 1 1 0 1 1 1 1 Snf7 DUF3490 PF11995.3 CBK21387.2 - 0.037 13.6 1.1 0.064 12.8 0.3 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3490) KAP_NTPase PF07693.9 CBK21387.2 - 0.086 11.8 0.3 0.15 11.0 0.2 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Enkurin PF13864.1 CBK21387.2 - 1 9.5 4.5 4.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Calmodulin-binding BING4CT PF08149.6 CBK21388.2 - 1.4e-30 104.6 0.0 5.8e-30 102.6 0.0 2.0 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CBK21388.2 - 0.00079 19.2 0.1 2.5 8.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat PRD PF00874.15 CBK21389.2 - 0.13 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 PRD domain SH3_1 PF00018.23 CBK21391.2 - 1.4e-28 98.0 2.9 2.1e-10 39.8 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBK21391.2 - 2.7e-27 94.0 1.2 6.2e-11 41.6 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.1 CBK21391.2 - 2.7e-27 94.0 2.8 3.7e-09 36.0 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.6 CBK21391.2 - 5.9e-07 29.5 3.7 0.52 10.5 0.2 3.6 3 0 0 3 3 3 3 Bacterial SH3 domain SH3_4 PF06347.8 CBK21391.2 - 0.00035 20.0 0.5 1.3 8.5 0.0 3.5 3 0 0 3 3 3 1 Bacterial SH3 domain Trypan_PARP PF05887.6 CBK21391.2 - 0.0069 16.2 38.8 0.0069 16.2 26.9 3.5 2 1 1 3 3 2 1 Procyclic acidic repetitive protein (PARP) PBP5_C PF07943.8 CBK21391.2 - 0.007 16.3 8.5 1.4 8.9 0.1 4.1 3 1 1 4 4 4 1 Penicillin-binding protein 5, C-terminal domain Methyltransf_5 PF01795.14 CBK21391.2 - 0.0083 15.4 6.2 0.11 11.7 0.3 2.7 1 1 2 3 3 3 2 MraW methylase family DUF237 PF03072.9 CBK21391.2 - 0.019 14.8 1.1 24 4.8 0.0 3.3 3 0 0 3 3 3 0 MG032/MG096/MG288 family 1 F1F0-ATPsyn_F PF10791.4 CBK21391.2 - 0.15 12.3 1.8 73 3.6 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF3892 PF13031.1 CBK21391.2 - 0.27 11.6 8.8 11 6.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) CaKB PF03185.10 CBK21391.2 - 6.4 6.1 12.1 7.8 5.8 0.5 3.1 1 1 2 3 3 3 0 Calcium-activated potassium channel, beta subunit Pyr_redox_2 PF07992.9 CBK21392.2 - 9.8e-45 152.9 2.4 4.1e-44 150.8 1.6 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBK21392.2 - 4.2e-38 129.7 0.1 9.6e-38 128.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBK21392.2 - 9.2e-21 74.0 8.6 3.9e-18 65.6 0.7 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK21392.2 - 4e-12 46.6 0.8 9.1e-05 22.6 0.1 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBK21392.2 - 5.1e-12 45.5 5.9 2.9e-11 43.0 0.2 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CBK21392.2 - 9.2e-12 44.5 3.1 1.3e-10 40.6 0.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBK21392.2 - 3.5e-07 29.0 9.2 0.00035 19.1 0.9 3.9 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.19 CBK21392.2 - 3.9e-07 29.2 2.5 3.9e-07 29.2 1.7 3.9 4 1 1 5 5 5 1 FAD binding domain DAO PF01266.19 CBK21392.2 - 2.3e-06 26.7 19.6 0.0008 18.4 0.4 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 CBK21392.2 - 3.9e-06 26.1 1.9 1.4e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CBK21392.2 - 4.1e-06 26.7 7.8 0.0011 18.9 1.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CBK21392.2 - 9.2e-05 21.6 13.8 0.012 14.6 0.6 3.3 2 1 1 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 CBK21392.2 - 0.00017 20.5 2.3 0.017 14.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CBK21392.2 - 0.013 15.0 1.6 0.43 10.1 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 CBK21392.2 - 0.023 13.8 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CBK21392.2 - 0.44 9.4 9.3 0.49 9.2 0.4 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein DUF872 PF05915.7 CBK21394.2 - 0.071 12.9 0.2 0.095 12.5 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TCRP1 PF14944.1 CBK21395.2 - 0.11 12.3 9.9 0.17 11.8 6.8 1.3 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 CHASE PF03924.8 CBK21395.2 - 0.53 9.4 3.4 0.81 8.8 2.4 1.4 1 1 0 1 1 1 0 CHASE domain DUF3449 PF11931.3 CBK21396.2 - 6.7e-68 228.0 5.6 6.7e-68 228.0 3.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 CBK21396.2 - 7.1e-15 54.0 0.0 2.1e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 CBK21396.2 - 4.5e-09 35.6 0.1 1.4e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain UPF0149 PF03695.8 CBK21396.2 - 0.0034 17.2 0.8 0.0034 17.2 0.6 2.2 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0149) Med11 PF10280.4 CBK21396.2 - 0.0052 16.8 1.2 0.014 15.4 0.9 1.8 1 0 0 1 1 1 1 Mediator complex protein Latarcin PF10279.4 CBK21396.2 - 0.088 13.0 8.7 8.6 6.6 0.0 4.8 3 3 1 4 4 4 0 Latarcin precursor Desulfoferrod_N PF06397.7 CBK21396.2 - 0.21 11.0 0.7 0.4 10.0 0.5 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DUF2175 PF09943.4 CBK21396.2 - 1.1 9.3 6.7 2.1 8.4 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) PTS_EIIC_2 PF13303.1 CBK21397.2 - 1.3e-99 333.1 47.9 1.5e-99 332.9 33.2 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PP2C PF00481.16 CBK21400.2 - 0.0014 18.1 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Dimer_Tnp_hAT PF05699.9 CBK21400.2 - 0.068 12.7 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Nitroreductase PF00881.19 CBK21401.2 - 9.6e-28 97.0 0.0 1.9e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 Nitroreductase family ATP_bind_1 PF03029.12 CBK21402.2 - 4.9e-65 219.3 0.1 1.2e-63 214.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBK21402.2 - 5e-05 24.1 0.1 0.00044 21.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CBK21402.2 - 0.0023 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 CBK21402.2 - 0.0092 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_31 PF13614.1 CBK21402.2 - 0.0095 15.8 0.0 0.21 11.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 CBK21402.2 - 0.014 15.5 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 CBK21402.2 - 0.017 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 CBK21402.2 - 0.02 14.3 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 CBK21402.2 - 0.026 14.8 0.2 0.071 13.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain T2SE PF00437.15 CBK21402.2 - 0.028 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CBK21402.2 - 0.052 13.4 0.1 0.14 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBK21402.2 - 0.078 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBK21402.2 - 0.081 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.1 CBK21402.2 - 0.082 13.2 0.7 0.17 12.2 0.5 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_29 PF13555.1 CBK21402.2 - 0.095 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 CBK21402.2 - 0.11 11.8 0.0 0.37 10.1 0.0 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 CBK21402.2 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBK21402.2 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain Peptidase_S8 PF00082.17 CBK21403.2 - 9.6e-40 136.4 0.1 1.3e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Subtilase family HSP20 PF00011.16 CBK21404.2 - 6.2e-27 93.4 1.7 7.3e-27 93.2 1.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family MmlI PF09448.5 CBK21404.2 - 0.03 14.0 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase HSP70 PF00012.15 CBK21406.2 - 2.3e-27 95.1 2.6 1.5e-23 82.5 0.0 2.5 2 1 1 3 3 3 2 Hsp70 protein TPR_11 PF13414.1 CBK21406.2 - 9.4e-19 66.8 4.1 7.5e-11 41.5 0.4 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBK21406.2 - 3.2e-11 42.3 2.0 0.0016 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK21406.2 - 1.2e-09 37.3 3.8 0.006 16.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21406.2 - 1.3e-08 34.9 1.1 0.0002 21.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBK21406.2 - 9.6e-05 22.4 2.5 0.00022 21.2 1.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBK21406.2 - 9.8e-05 22.5 2.2 1.5 9.4 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21406.2 - 0.00027 21.3 0.1 0.031 14.8 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21406.2 - 0.00029 21.4 0.3 0.011 16.4 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK21406.2 - 0.00032 20.2 0.7 1.4 8.9 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat FGGY_C PF02782.11 CBK21406.2 - 0.00038 20.1 0.1 0.00083 19.0 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Fis1_TPR_C PF14853.1 CBK21406.2 - 0.00042 20.1 0.2 0.61 10.0 0.0 3.8 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CBK21406.2 - 0.00059 19.4 0.0 0.0082 15.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK21406.2 - 0.0021 17.8 1.5 0.0042 16.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK21406.2 - 0.0076 16.1 0.8 0.29 11.0 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK21406.2 - 0.027 14.6 0.1 0.17 12.1 0.0 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat SIP PF04954.8 CBK21406.2 - 0.028 14.8 0.5 0.073 13.4 0.4 1.7 1 0 0 1 1 1 0 Siderophore-interacting protein MIT PF04212.13 CBK21406.2 - 0.038 13.8 3.4 0.04 13.7 0.1 2.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain MutL PF13941.1 CBK21406.2 - 0.046 12.0 0.0 0.076 11.3 0.0 1.3 1 0 0 1 1 1 0 MutL protein MreB_Mbl PF06723.8 CBK21406.2 - 0.089 11.3 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein HisKA_3 PF07730.8 CBK21406.2 - 5.4 7.4 9.9 13 6.1 0.2 3.5 3 0 0 3 3 3 0 Histidine kinase Ndufs5 PF10200.4 CBK21407.2 - 0.0011 18.9 1.9 0.0014 18.5 1.3 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PRE_C2HC PF07530.6 CBK21407.2 - 0.023 14.6 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Associated with zinc fingers CHCH PF06747.8 CBK21407.2 - 0.032 14.1 0.3 0.032 14.1 0.2 2.4 3 0 0 3 3 3 0 CHCH domain Pet191_N PF10203.4 CBK21407.2 - 0.073 13.1 1.7 0.11 12.6 1.2 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 CBK21407.2 - 0.56 10.0 5.4 7.5 6.4 0.2 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF3128 PF11326.3 CBK21407.2 - 3.4 7.8 9.5 1.1e+02 3.0 6.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) adh_short PF00106.20 CBK21408.2 - 0.0025 17.7 1.7 0.029 14.2 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Coatomer_E PF04733.9 CBK21410.2 - 3.7e-11 42.7 0.0 3.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit DUF3595 PF12166.3 CBK21411.2 - 2.4e-42 145.2 5.2 2.9e-42 144.9 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) DUF3028 PF11229.3 CBK21411.2 - 0.076 11.2 0.1 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) RRM_1 PF00076.17 CBK21412.2 - 2e-35 120.2 0.0 2.3e-22 78.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21412.2 - 5.6e-27 93.5 0.0 1.6e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21412.2 - 2e-15 56.3 0.0 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 CBK21412.2 - 0.027 13.7 23.3 0.033 13.4 16.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MIP-T3 PF10243.4 CBK21412.2 - 0.088 11.2 70.9 0.12 10.8 49.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 EF-hand_1 PF00036.27 CBK21413.2 - 4.9e-10 37.9 2.6 0.0013 17.9 0.0 4.0 3 1 2 5 5 5 2 EF hand EF-hand_6 PF13405.1 CBK21413.2 - 1.4e-09 37.0 2.2 0.0049 16.6 0.0 3.9 3 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBK21413.2 - 2.7e-09 37.0 1.6 1.3e-08 34.8 0.5 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBK21413.2 - 7.8e-07 28.6 1.5 0.00026 20.5 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK21413.2 - 1.2e-05 24.4 2.5 0.044 13.1 0.0 3.5 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CBK21413.2 - 0.0032 17.4 4.2 0.016 15.2 2.9 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TFIIB PF00382.14 CBK21415.2 - 9e-34 115.1 1.3 2.4e-16 59.3 0.0 3.2 2 1 1 3 3 3 3 Transcription factor TFIIB repeat BRF1 PF07741.8 CBK21415.2 - 1.5e-17 63.6 6.0 1.5e-17 63.6 4.1 2.1 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CBK21415.2 - 3.7e-07 29.3 4.8 3.7e-07 29.3 3.4 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 CBK21415.2 - 1.4e-05 24.6 0.6 0.0092 15.5 0.1 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 CBK21415.2 - 7.9 5.8 7.2 24 4.3 1.0 2.2 1 1 1 2 2 2 0 zinc-ribbon domain FKBP_C PF00254.23 CBK21417.2 - 2.4e-27 94.7 0.0 3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sad1_UNC PF07738.8 CBK21418.2 - 0.00021 21.0 0.0 0.00078 19.2 0.0 1.8 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF869 PF05911.6 CBK21418.2 - 0.0066 14.7 0.9 0.0089 14.3 0.6 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) BLOC1_2 PF10046.4 CBK21418.2 - 0.012 15.7 1.8 0.16 12.1 0.6 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.6 CBK21418.2 - 0.019 13.4 1.0 0.024 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tnp_P_element PF12017.3 CBK21418.2 - 0.038 13.2 0.9 0.077 12.2 0.2 1.7 1 1 1 2 2 2 0 Transposase protein Tropomyosin_1 PF12718.2 CBK21418.2 - 0.062 13.1 1.2 0.068 13.0 0.1 1.5 2 0 0 2 2 2 0 Tropomyosin like GAS PF13851.1 CBK21419.2 - 0.00093 18.4 13.3 0.00093 18.4 9.2 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 CBK21419.2 - 0.0065 16.1 12.3 0.0065 16.1 8.5 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding OmpH PF03938.9 CBK21419.2 - 0.0098 15.8 9.1 0.012 15.5 6.3 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Apt1 PF10351.4 CBK21419.2 - 0.013 14.4 4.8 0.013 14.3 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain KH_5 PF13184.1 CBK21419.2 - 0.044 13.5 0.8 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 NusA-like KH domain PXA PF02194.10 CBK21419.2 - 0.051 13.1 3.9 0.085 12.4 2.7 1.4 1 0 0 1 1 1 0 PXA domain DUF812 PF05667.6 CBK21419.2 - 0.054 11.9 9.1 0.065 11.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2058 PF09831.4 CBK21419.2 - 0.16 11.8 12.9 0.024 14.5 6.2 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Radial_spoke_3 PF06098.6 CBK21419.2 - 0.17 10.8 14.6 0.2 10.6 10.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Arc_PepC_II PF06847.6 CBK21419.2 - 0.18 12.2 3.5 0.41 11.1 1.2 2.3 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II CENP-H PF05837.7 CBK21419.2 - 0.19 11.9 15.1 0.068 13.3 7.4 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 CBK21419.2 - 0.39 9.7 14.7 0.046 12.7 7.0 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Lipoprotein_20 PF13942.1 CBK21419.2 - 0.55 9.7 9.0 0.2 11.1 4.1 1.7 2 0 0 2 2 2 0 YfhG lipoprotein DivIC PF04977.10 CBK21419.2 - 0.66 9.5 23.6 0.2 11.1 5.1 3.1 2 1 1 3 3 3 0 Septum formation initiator Vps51 PF08700.6 CBK21419.2 - 0.85 9.5 0.0 0.85 9.5 0.0 3.1 2 1 0 2 2 1 0 Vps51/Vps67 DegS PF05384.6 CBK21419.2 - 1.4 8.0 15.7 7.4 5.7 10.9 2.1 1 1 0 1 1 1 0 Sensor protein DegS Allexi_40kDa PF05549.6 CBK21419.2 - 1.4 8.1 4.2 21 4.2 1.5 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CDC37_N PF03234.9 CBK21419.2 - 1.5 9.0 12.0 1.4 9.2 5.7 2.3 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Mnd1 PF03962.10 CBK21419.2 - 2.1 8.0 13.5 0.36 10.4 6.3 1.8 2 0 0 2 2 2 0 Mnd1 family DUF4337 PF14235.1 CBK21419.2 - 2.6 7.8 8.7 2.3 8.0 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DivIVA PF05103.8 CBK21419.2 - 2.9 7.9 17.4 16 5.5 12.1 2.3 1 1 0 1 1 1 0 DivIVA protein V_ATPase_I PF01496.14 CBK21419.2 - 2.9 5.6 7.3 3.2 5.5 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4163 PF13739.1 CBK21419.2 - 3.2 8.5 5.2 3.2 8.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) DIRP PF06584.8 CBK21419.2 - 4.9 7.0 9.2 0.81 9.5 0.6 2.3 1 1 1 2 2 2 0 DIRP IncA PF04156.9 CBK21419.2 - 5 6.6 19.3 10 5.6 13.3 1.5 1 1 0 1 1 1 0 IncA protein RCC1 PF00415.13 CBK21420.2 - 2.1e-49 165.5 14.8 2.1e-13 50.2 0.7 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Ala_racemase_N PF01168.15 CBK21420.2 - 6.9e-38 130.3 0.0 9.3e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain RCC1_2 PF13540.1 CBK21420.2 - 2.8e-24 84.1 31.2 4.5e-09 35.6 0.5 4.6 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Sld5 PF05916.6 CBK21421.2 - 0.00024 21.3 0.3 0.00035 20.8 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein Pox_int_trans PF05718.7 CBK21421.2 - 0.017 13.7 0.3 0.024 13.1 0.2 1.3 1 1 0 1 1 1 0 Poxvirus intermediate transcription factor MCM PF00493.18 CBK21422.2 - 1.2e-127 425.2 0.0 1.5e-127 424.9 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBK21422.2 - 1.2e-09 37.6 0.1 2.4e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBK21422.2 - 0.00063 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBK21422.2 - 0.00096 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK21422.2 - 0.0014 18.3 0.0 0.0047 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBK21422.2 - 0.0018 17.7 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM_N PF14551.1 CBK21422.2 - 0.051 14.0 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 MCM N-terminal domain Ribosomal_L5_C PF00673.16 CBK21423.2 - 2.8e-22 78.2 0.0 4e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBK21423.2 - 2.7e-18 65.4 0.6 1.4e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 DUF1681 PF07933.9 CBK21424.2 - 1.6e-24 86.2 0.1 2.6e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SMN PF06003.7 CBK21424.2 - 0.012 14.6 0.5 0.016 14.3 0.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) AMP-binding PF00501.23 CBK21425.2 - 8.4e-69 231.9 0.0 1.9e-68 230.7 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBK21425.2 - 0.0038 18.1 0.0 0.0099 16.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Complex1_LYR PF05347.10 CBK21426.2 - 2e-05 24.2 0.1 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_6 PF14259.1 CBK21427.2 - 6.6e-14 51.6 0.0 0.00022 21.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21427.2 - 6e-12 45.2 0.2 5.8e-05 22.8 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK21427.2 - 8.4e-11 41.3 0.0 0.0006 19.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SurE PF01975.12 CBK21427.2 - 0.0019 17.5 0.0 0.0069 15.7 0.1 1.9 2 0 0 2 2 2 1 Survival protein SurE Laminin_B PF00052.13 CBK21427.2 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) YihI PF04220.7 CBK21427.2 - 0.11 11.8 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Der GTPase activator (YihI) Corona_nucleoca PF00937.13 CBK21427.2 - 0.56 9.1 9.2 0.92 8.3 6.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ribosomal_S15 PF00312.17 CBK21428.2 - 9.6e-24 82.9 4.5 1.2e-23 82.6 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 DivIC PF04977.10 CBK21429.2 - 0.0034 16.8 0.4 0.0034 16.8 0.3 5.9 3 1 3 6 6 6 1 Septum formation initiator MLANA PF14991.1 CBK21429.2 - 0.023 14.7 0.0 0.079 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein melan-A ODV-E18 PF10717.4 CBK21429.2 - 0.037 13.4 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Laminin_EGF PF00053.19 CBK21429.2 - 0.052 13.4 1.8 0.11 12.4 1.2 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DUF4448 PF14610.1 CBK21429.2 - 0.11 11.9 1.3 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) LMBR1 PF04791.11 CBK21429.2 - 0.42 9.1 7.0 0.29 9.6 3.4 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.10 CBK21429.2 - 0.51 9.4 14.9 0.027 13.6 6.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit C1_2 PF03107.11 CBK21429.2 - 0.65 10.1 0.1 0.65 10.1 0.1 2.7 2 1 0 2 2 2 0 C1 domain OGG_N PF07934.7 CBK21429.2 - 1.9 8.4 7.5 0.63 10.0 1.7 2.4 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain bZIP_1 PF00170.16 CBK21429.2 - 5.4 7.0 30.6 0.59 10.1 2.0 4.9 4 2 1 5 5 5 0 bZIP transcription factor eRF1_3 PF03465.10 CBK21430.2 - 3.2e-40 136.9 0.1 6.4e-40 135.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 CBK21430.2 - 2.5e-38 131.3 0.0 3.9e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_1 PF03463.10 CBK21430.2 - 9.4e-26 89.9 0.0 1.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Glyco_tran_28_C PF04101.11 CBK21431.2 - 6.8e-27 94.1 0.0 7.8e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Transketolase_C PF02780.15 CBK21431.2 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 Transketolase, C-terminal domain Glyco_trans_1_3 PF13528.1 CBK21431.2 - 0.031 13.4 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 MerC PF03203.9 CBK21432.2 - 0.15 12.4 1.3 0.16 12.3 0.9 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DNA_pol_B_2 PF03175.8 CBK21433.2 - 2.5e-09 36.3 14.3 1.1e-06 27.6 9.9 3.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Glyco_tran_28_C PF04101.11 CBK21434.2 - 6.8e-27 94.1 0.0 7.8e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Transketolase_C PF02780.15 CBK21434.2 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 Transketolase, C-terminal domain Glyco_trans_1_3 PF13528.1 CBK21434.2 - 0.031 13.4 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Pkinase PF00069.20 CBK21435.2 - 4.9e-38 130.7 0.0 6.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21435.2 - 4.8e-19 68.4 0.0 7.2e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21435.2 - 0.00077 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK21435.2 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBK21435.2 - 0.0071 15.7 0.1 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 CBK21435.2 - 0.034 13.1 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK21435.2 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L17 PF01196.14 CBK21436.2 - 1.6e-20 73.4 1.7 2.3e-20 72.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Prefoldin_3 PF13758.1 CBK21436.2 - 0.0028 17.3 0.4 0.0032 17.2 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Acyl-CoA_dh_2 PF08028.6 CBK21436.2 - 0.27 11.5 3.3 0.32 11.2 2.3 1.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_11 PF08241.7 CBK21438.2 - 2e-05 25.0 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK21438.2 - 0.00021 21.6 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBK21438.2 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBK21438.2 - 0.0059 16.2 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RNA_pol_N PF01194.12 CBK21439.2 - 2.7e-29 100.9 0.6 3.2e-29 100.7 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 CBK21439.2 - 0.11 12.2 0.3 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 YhfH-like protein DUF2053 PF09767.4 CBK21440.2 - 2.8e-25 89.1 10.5 6.4e-25 87.9 7.3 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2053) PetN PF03742.9 CBK21440.2 - 1.9 8.1 6.6 11 5.6 0.0 2.5 2 0 0 2 2 2 0 PetN E1-E2_ATPase PF00122.15 CBK21441.2 - 5.5e-66 221.8 0.6 1.7e-65 220.2 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK21441.2 - 6.5e-49 165.9 0.6 6.5e-49 165.9 0.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK21441.2 - 1.4e-28 100.8 0.1 2e-27 97.0 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK21441.2 - 2.7e-23 81.7 0.0 4.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBK21441.2 - 1.4e-19 69.3 0.3 6.2e-19 67.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBK21441.2 - 1.5e-12 48.0 0.0 4.2e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK21441.2 - 6e-06 26.0 0.4 0.00031 20.3 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PPR_2 PF13041.1 CBK21442.2 - 7.6e-39 131.4 0.1 2.5e-08 33.7 0.0 9.2 3 3 6 9 9 9 8 PPR repeat family PPR PF01535.15 CBK21442.2 - 4.2e-25 85.9 5.6 0.0028 17.5 0.0 9.8 10 1 0 10 10 10 6 PPR repeat PPR_3 PF13812.1 CBK21442.2 - 1.5e-24 84.1 0.9 0.0097 16.1 0.1 9.5 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBK21442.2 - 1.7e-17 62.5 0.0 0.00028 20.3 0.0 6.0 6 0 0 6 6 6 4 PPR repeat TPR_16 PF13432.1 CBK21442.2 - 0.00044 20.8 0.0 1.1 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank_2 PF12796.2 CBK21443.2 - 2.2e-37 127.2 6.1 4.3e-13 49.4 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21443.2 - 1.4e-27 94.0 11.8 1.4e-07 30.9 0.4 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CBK21443.2 - 4.1e-22 77.6 9.9 5.9e-09 35.8 0.2 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK21443.2 - 4.2e-21 72.9 7.5 5.4e-05 23.0 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CBK21443.2 - 3.1e-18 65.7 6.2 6.3e-09 36.1 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) cwf18 PF08315.7 CBK21444.2 - 1.3e-14 54.8 7.9 1.9e-14 54.2 5.5 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor ApbA PF02558.11 CBK21444.2 - 0.14 11.6 0.2 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4463 PF14703.1 CBK21444.2 - 0.54 10.8 4.4 0.72 10.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Peptidase_S8 PF00082.17 CBK21445.2 - 8.3e-45 153.1 0.1 1e-44 152.8 0.1 1.1 1 0 0 1 1 1 1 Subtilase family AA_permease_2 PF13520.1 CBK21446.2 - 0.0021 16.6 0.1 0.0021 16.6 0.1 1.1 1 0 0 1 1 1 1 Amino acid permease Amnionless PF14828.1 CBK21446.2 - 0.0063 15.0 0.1 0.0066 14.9 0.1 1.0 1 0 0 1 1 1 1 Amnionless DUF912 PF06024.7 CBK21446.2 - 0.039 13.9 0.8 0.09 12.8 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1406 PF07190.6 CBK21446.2 - 0.043 13.5 0.2 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1406) ODV-E18 PF10717.4 CBK21446.2 - 0.062 12.7 0.6 0.18 11.2 0.4 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 LRRC37AB_C PF14914.1 CBK21446.2 - 0.078 12.4 0.3 0.096 12.1 0.2 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Peptidase_M76 PF09768.4 CBK21446.2 - 0.097 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Protocadherin PF08374.6 CBK21446.2 - 0.11 12.1 0.9 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.1 CBK21446.2 - 0.27 10.9 3.5 0.45 10.2 2.3 1.5 1 1 0 1 1 1 0 TMEM154 protein family DUF3753 PF12575.3 CBK21446.2 - 0.53 10.1 4.1 0.67 9.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Shisa PF13908.1 CBK21446.2 - 0.69 10.0 4.8 0.76 9.9 2.9 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.3 CBK21446.2 - 0.71 10.4 2.5 1.6 9.2 1.8 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.1 CBK21446.2 - 0.71 10.3 4.0 1.8 9.0 2.8 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CBK21446.2 - 3.9 7.0 5.3 7.6 6.0 3.9 1.3 1 1 0 1 1 1 0 Rifin/stevor family P12 PF12669.2 CBK21446.2 - 3.9 7.7 5.2 7.3 6.8 3.6 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family Proteasome PF00227.21 CBK21448.2 - 2.9e-42 144.1 2.8 6.3e-42 143.0 1.9 1.5 1 1 0 1 1 1 1 Proteasome subunit Exo_endo_phos PF03372.18 CBK21449.2 - 1.4e-06 28.4 0.0 1.8e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Motile_Sperm PF00635.21 CBK21449.2 - 0.00091 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain F-box-like PF12937.2 CBK21449.2 - 0.086 12.5 0.1 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like eIF-1a PF01176.14 CBK21450.2 - 1.3e-27 95.0 1.0 1.8e-27 94.5 0.7 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HSBP1 PF06825.7 CBK21451.2 - 0.00075 19.0 2.5 0.0086 15.6 0.1 2.2 1 1 1 2 2 2 1 Heat shock factor binding protein 1 Striatin PF08232.7 CBK21451.2 - 0.019 15.3 0.8 0.022 15.0 0.6 1.2 1 0 0 1 1 1 0 Striatin family bZIP_2 PF07716.10 CBK21451.2 - 0.02 14.7 5.3 0.52 10.1 2.0 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF3373 PF11853.3 CBK21451.2 - 0.023 13.2 0.6 0.022 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) bZIP_1 PF00170.16 CBK21451.2 - 0.074 13.0 5.6 0.91 9.5 2.0 2.1 1 1 1 2 2 2 0 bZIP transcription factor CALCOCO1 PF07888.6 CBK21451.2 - 0.086 11.1 1.8 0.092 11.0 1.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ribosomal_L29 PF00831.18 CBK21451.2 - 0.12 12.0 5.3 0.28 10.8 1.7 2.0 1 1 1 2 2 2 0 Ribosomal L29 protein XhlA PF10779.4 CBK21451.2 - 0.13 12.2 1.9 0.17 11.8 1.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TMF_DNA_bd PF12329.3 CBK21451.2 - 0.13 12.0 6.4 0.23 11.2 4.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 CBK21451.2 - 0.14 12.4 0.5 0.16 12.2 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.1 CBK21451.2 - 0.36 10.9 3.4 2.3 8.3 2.3 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CBK21451.2 - 2.1 7.9 5.6 2.3 7.7 2.1 1.9 1 1 1 2 2 2 0 Septum formation initiator MtrG PF04210.8 CBK21451.2 - 6.2 6.5 5.6 12 5.6 2.4 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G HSBP1 PF06825.7 CBK21452.2 - 9.5e-08 31.4 1.0 9.9e-08 31.4 0.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 TMF_TATA_bd PF12325.3 CBK21453.2 - 0.032 13.9 13.2 0.022 14.4 1.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding VWA_3 PF13768.1 CBK21453.2 - 0.073 12.7 0.3 0.15 11.7 0.1 1.6 1 1 1 2 2 2 0 von Willebrand factor type A domain FUSC PF04632.7 CBK21453.2 - 0.1 11.0 1.9 0.096 11.1 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phlebovirus_NSM PF07246.6 CBK21453.2 - 0.16 11.1 10.0 0.12 11.5 0.8 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Toxin_trans PF07952.7 CBK21453.2 - 0.18 10.7 5.0 0.2 10.5 3.5 1.0 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF4140 PF13600.1 CBK21453.2 - 0.33 11.4 13.7 0.16 12.4 3.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HrpA_pilin PF09589.5 CBK21453.2 - 0.42 11.0 7.8 0.11 12.8 3.0 1.8 2 0 0 2 2 2 0 HrpA pilus formation protein Init_tRNA_PT PF04179.7 CBK21453.2 - 0.88 8.3 5.8 1.1 8.0 4.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Muted PF14942.1 CBK21453.2 - 1.4 8.8 16.0 2.1 8.2 2.3 2.1 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein PilJ PF13675.1 CBK21453.2 - 1.5 9.1 7.3 0.91 9.8 3.5 1.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.3 CBK21453.2 - 2 8.3 13.9 3.2 7.6 2.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NTPase_1 PF03266.10 CBK21453.2 - 2.3 7.9 4.9 1.9 8.1 0.5 2.0 1 1 1 2 2 2 0 NTPase KfrA_N PF11740.3 CBK21453.2 - 2.3 8.6 13.8 19 5.7 6.7 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CDC37_N PF03234.9 CBK21453.2 - 2.3 8.4 12.2 3.1 8.0 8.5 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Ax_dynein_light PF10211.4 CBK21453.2 - 2.4 7.9 16.0 4 7.2 3.4 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain CENP-H PF05837.7 CBK21453.2 - 3.2 7.9 13.2 0.85 9.8 2.0 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TMCO5 PF14992.1 CBK21453.2 - 3.7 6.6 17.9 0.038 13.1 3.0 2.0 1 1 0 2 2 2 0 TMCO5 family DUF2360 PF10152.4 CBK21453.2 - 4.4 7.5 9.5 9.9 6.4 6.2 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1706 PF08020.6 CBK21453.2 - 4.5 6.7 8.4 3.4 7.1 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) cwf18 PF08315.7 CBK21453.2 - 4.5 7.7 12.5 15 6.0 8.7 1.8 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor MRP-S26 PF14943.1 CBK21453.2 - 5.7 6.4 19.6 1.4 8.3 2.7 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF4407 PF14362.1 CBK21453.2 - 6.4 5.6 12.9 9.2 5.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_E PF05680.7 CBK21453.2 - 9.6 6.2 12.5 2.8 7.9 1.7 2.2 2 0 0 2 2 2 0 ATP synthase E chain Ank_2 PF12796.2 CBK21454.2 - 1.1e-47 160.2 34.4 2.5e-14 53.3 0.5 8.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21454.2 - 5.7e-33 111.0 24.7 7e-06 25.5 0.0 11.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 CBK21454.2 - 3e-30 103.5 25.0 0.001 19.2 0.1 11.5 6 3 7 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK21454.2 - 2.1e-29 98.5 20.4 9.6e-05 22.2 0.0 12.4 12 0 0 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 CBK21454.2 - 1.2e-28 98.9 27.5 3.2e-06 27.4 0.0 11.2 6 3 7 13 13 13 8 Ankyrin repeats (many copies) Glycos_transf_2 PF00535.21 CBK21455.2 - 1.8e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Oxidored_q1_C PF01010.14 CBK21455.2 - 0.00048 19.7 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Glyco_transf_7C PF02709.9 CBK21455.2 - 0.0017 17.8 1.6 0.0025 17.2 0.3 1.9 1 1 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBK21455.2 - 0.022 14.5 0.3 0.28 10.9 0.1 2.4 2 1 0 2 2 2 0 Glycosyltransferase like family 2 GlcNAc PF11397.3 CBK21455.2 - 0.035 13.2 0.3 0.66 9.0 0.2 2.0 2 0 0 2 2 2 0 Glycosyltransferase (GlcNAc) Hexapep PF00132.19 CBK21456.2 - 7.6e-14 50.5 12.2 2.7e-06 26.6 0.1 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBK21456.2 - 0.23 11.0 9.4 28 4.3 4.0 3.9 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DEAD PF00270.24 CBK21457.2 - 4.1e-28 97.9 0.1 9.2e-28 96.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21457.2 - 1.8e-14 53.3 0.0 4.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21457.2 - 1.3e-06 28.3 0.0 4.6e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBK21457.2 - 0.0072 16.4 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBK21457.2 - 0.008 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK21457.2 - 0.046 12.6 0.0 0.67 8.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Helicase_C_2 PF13307.1 CBK21457.2 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Aminotran_1_2 PF00155.16 CBK21458.2 - 4.8e-09 35.6 0.0 8.4e-09 34.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Ank_2 PF12796.2 CBK21459.2 - 4.1e-47 158.4 17.1 6.1e-18 64.9 1.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21459.2 - 3.9e-24 83.1 10.7 0.00012 21.7 0.2 6.1 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 CBK21459.2 - 2.7e-21 73.5 6.2 0.00058 19.8 0.1 5.6 6 0 0 6 6 5 5 Ankyrin repeat Ank_4 PF13637.1 CBK21459.2 - 4.9e-21 74.6 0.6 3.7e-07 30.4 0.3 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) TPR_11 PF13414.1 CBK21459.2 - 1.2e-19 69.6 0.0 2.2e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 TPR repeat Ank_5 PF13857.1 CBK21459.2 - 3e-18 65.4 7.5 1.1e-08 35.0 0.3 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) TPR_1 PF00515.23 CBK21459.2 - 4.8e-12 44.9 0.0 0.00048 19.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK21459.2 - 5.3e-11 41.5 0.0 0.0012 18.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBK21459.2 - 2e-07 30.6 0.0 0.00042 20.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK21459.2 - 2.1e-07 30.2 0.0 0.012 15.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK21459.2 - 2.6e-06 27.2 0.0 0.0024 17.7 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21459.2 - 9.8e-06 26.1 0.0 0.0038 17.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21459.2 - 5.4e-05 23.4 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21459.2 - 0.00069 20.0 0.0 3.6 8.4 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat NYD-SP12_N PF15015.1 CBK21459.2 - 0.0015 16.8 0.2 0.0027 16.0 0.0 1.4 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal TPR_6 PF13174.1 CBK21459.2 - 0.0085 16.4 0.1 2.3 8.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBK21459.2 - 0.01 15.8 0.1 0.05 13.7 0.0 2.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK21459.2 - 0.031 14.1 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Fe-S_biosyn PF01521.15 CBK21460.2 - 7.8e-20 70.8 0.0 1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 CBK21460.2 - 0.035 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) SPARC_Ca_bdg PF10591.4 CBK21461.2 - 0.89 9.6 4.1 1 9.3 0.2 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 CBK21462.2 - 8.8e-38 129.9 0.0 8.8e-38 129.9 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21462.2 - 4.3e-20 71.8 0.0 4.3e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK21462.2 - 9.6e-06 25.4 0.0 0.00051 19.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK21462.2 - 0.0022 17.0 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBK21462.2 - 0.0061 15.4 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUSP PF06337.7 CBK21463.2 - 1.8e-09 37.9 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 DUSP domain zf-MYND PF01753.13 CBK21463.2 - 2e-09 37.1 8.9 4.5e-09 36.0 6.2 1.7 1 0 0 1 1 1 1 MYND finger UCH PF00443.24 CBK21463.2 - 2.7e-09 36.5 0.0 4.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21463.2 - 0.0037 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.11 CBK21463.2 - 0.0058 16.2 7.2 0.0058 16.2 5.0 2.9 4 0 0 4 4 4 1 HIT zinc finger UCH PF00443.24 CBK21464.2 - 2.3e-25 89.2 0.0 2.4e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21464.2 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NADH_u_ox_C PF12853.2 CBK21464.2 - 0.084 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Metallophos PF00149.23 CBK21465.2 - 3.2e-43 147.4 0.6 4e-43 147.1 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_His PF13393.1 CBK21466.2 - 1.1e-43 149.4 0.0 1.1e-43 149.4 0.0 2.5 2 1 1 3 3 3 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CBK21466.2 - 5.3e-19 68.4 0.0 7.5e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK21466.2 - 5.5e-17 61.5 0.2 1.6e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 CBK21466.2 - 6.1e-09 35.4 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 CBK21466.2 - 1.9e-06 26.9 0.0 3.4e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CBK21466.2 - 0.088 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF4515 PF14988.1 CBK21466.2 - 0.39 10.3 5.8 1 8.9 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) TRAM_LAG1_CLN8 PF03798.11 CBK21467.2 - 8.4e-23 80.9 21.6 8.4e-23 80.9 15.0 1.5 2 0 0 2 2 2 1 TLC domain DUF788 PF05620.6 CBK21467.2 - 0.17 11.7 0.1 0.17 11.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Nucleoplasmin PF03066.10 CBK21467.2 - 3.6 7.0 9.5 5.7 6.4 6.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 CBK21467.2 - 7.6 4.4 10.7 57 1.5 7.6 1.9 2 0 0 2 2 2 0 CDC45-like protein ChW PF07538.6 CBK21468.2 - 3.4e-45 151.2 12.1 6.1e-15 54.4 0.1 6.0 6 0 0 6 6 6 5 Clostridial hydrophobic W PepSY_TM_1 PF13172.1 CBK21469.2 - 0.093 12.5 0.3 0.093 12.5 0.2 1.8 2 0 0 2 2 2 0 PepSY-associated TM helix Nol1_Nop2_Fmu PF01189.12 CBK21470.2 - 1.7e-95 319.6 0.0 2.8e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CBK21470.2 - 6e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CBK21470.2 - 0.0017 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Collagen PF01391.13 CBK21470.2 - 0.017 14.6 9.5 0.039 13.4 6.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Methyltransf_18 PF12847.2 CBK21470.2 - 0.083 13.4 0.3 0.39 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Adap_comp_sub PF00928.16 CBK21471.2 - 1.8e-82 276.3 0.0 2.3e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK21471.2 - 0.00013 21.7 4.0 0.00019 21.1 2.5 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 CBK21471.2 - 0.093 12.3 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain SNF2_N PF00176.18 CBK21472.2 - 8.6e-63 211.8 0.5 1.5e-62 211.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK21472.2 - 3e-16 59.0 0.2 1e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 CBK21472.2 - 1.3e-10 40.7 0.7 3.5e-10 39.3 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.3 CBK21472.2 - 3.6e-08 32.5 0.0 1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBK21472.2 - 3.3e-05 23.4 0.1 0.00015 21.3 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK21472.2 - 0.00034 20.4 0.0 0.003 17.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1949 PF09186.6 CBK21474.2 - 0.0036 16.8 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) DNA_pol_B_2 PF03175.8 CBK21475.2 - 2.9e-09 36.1 7.6 0.0012 17.6 0.2 3.5 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral ABC_tran PF00005.22 CBK21476.2 - 2.9e-18 66.4 0.0 5.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK21476.2 - 2.5e-09 37.5 0.1 4.2e-09 36.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CBK21476.2 - 0.00071 18.8 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBK21476.2 - 0.0077 16.1 0.1 0.054 13.4 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IP_trans PF02121.13 CBK21479.2 - 1.3e-23 83.4 0.2 2.2e-22 79.4 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein ELYS PF13934.1 CBK21479.2 - 0.041 13.6 0.6 4.3 6.9 0.2 2.2 1 1 1 2 2 2 0 Nuclear pore complex assembly RepC PF06504.6 CBK21480.2 - 0.068 12.1 0.1 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) DUF3813 PF12758.2 CBK21481.2 - 0.0072 16.4 0.9 0.0072 16.4 0.6 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3813) Atg14 PF10186.4 CBK21481.2 - 0.074 11.9 10.3 0.16 10.9 7.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec34 PF04136.10 CBK21481.2 - 0.33 10.6 4.6 2.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Sec34-like family FUSC PF04632.7 CBK21481.2 - 0.35 9.2 5.9 0.4 9.0 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CK2S PF15011.1 CBK21481.2 - 0.36 10.6 12.1 0.21 11.3 1.1 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate PAS_7 PF12860.2 CBK21481.2 - 0.4 10.7 3.7 0.92 9.5 0.7 2.5 1 1 1 2 2 2 0 PAS fold DUF948 PF06103.6 CBK21481.2 - 0.46 10.3 2.9 0.41 10.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.2 CBK21481.2 - 3.5 6.8 24.6 0.056 12.7 11.4 2.0 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Mito_carr PF00153.22 CBK21482.2 - 5.5e-70 231.1 1.1 7.7e-24 83.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA_25 PF13481.1 CBK21484.2 - 1.6e-24 86.4 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBK21484.2 - 2e-13 50.0 0.0 4.5e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 KaiC ChlI PF13541.1 CBK21484.2 - 9.4e-12 44.5 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.10 CBK21484.2 - 2.4e-07 29.8 0.0 7.1e-06 25.0 0.0 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 CBK21484.2 - 2.9e-05 24.1 0.1 5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBK21484.2 - 6.1e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CBK21484.2 - 0.00012 21.7 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK21484.2 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBK21484.2 - 0.00076 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.8 CBK21484.2 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain NACHT PF05729.7 CBK21484.2 - 0.0049 16.5 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Rad51 PF08423.6 CBK21484.2 - 0.0057 15.5 0.0 0.026 13.4 0.0 1.9 1 1 0 1 1 1 1 Rad51 GvpD PF07088.6 CBK21484.2 - 0.014 13.7 0.1 0.13 10.5 0.0 2.1 1 1 0 1 1 1 0 GvpD gas vesicle protein NTPase_1 PF03266.10 CBK21484.2 - 0.015 14.9 0.0 0.091 12.4 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CBK21484.2 - 0.028 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 CBK21484.2 - 0.037 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CBK21484.2 - 0.045 14.0 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CBK21484.2 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CBK21484.2 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 CBK21484.2 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_31 PF13614.1 CBK21484.2 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SF-assemblin PF06705.6 CBK21485.2 - 0.054 12.6 0.1 0.061 12.4 0.0 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin FadA PF09403.5 CBK21487.2 - 0.083 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA MoeZ_MoeB PF05237.8 CBK21487.2 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain DUF2129 PF09902.4 CBK21489.2 - 0.056 13.2 0.9 0.064 13.0 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Glyco_transf_49 PF13896.1 CBK21490.2 - 1.5e-08 34.1 3.3 1.9e-07 30.4 0.1 2.5 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK21490.2 - 0.00073 19.2 1.0 0.0023 17.6 0.4 1.9 1 1 1 2 2 2 2 F-box associated Ku_PK_bind PF08785.6 CBK21491.2 - 0.06 13.2 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like Toxin_25 PF08095.6 CBK21493.2 - 0.28 10.9 1.7 0.77 9.5 1.2 1.7 1 0 0 1 1 1 0 Hefutoxin family Pkinase PF00069.20 CBK21494.2 - 3.4e-35 121.4 0.0 4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21494.2 - 2.2e-14 53.1 0.0 2.7e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK21494.2 - 0.00037 20.2 0.0 0.0012 18.6 0.0 1.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBK21494.2 - 0.033 12.9 0.1 0.055 12.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_M41 PF01434.13 CBK21495.2 - 4.3e-51 173.4 0.1 7.1e-51 172.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBK21495.2 - 4.2e-41 140.2 0.0 8.5e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK21495.2 - 2.5e-05 23.9 0.0 0.0001 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBK21495.2 - 3.6e-05 23.4 0.3 0.00014 21.5 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CBK21495.2 - 3.8e-05 23.8 0.3 0.0034 17.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK21495.2 - 7.1e-05 22.8 0.2 0.00084 19.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 CBK21495.2 - 0.00011 21.0 0.0 0.00018 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBK21495.2 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBK21495.2 - 0.0002 22.1 0.1 0.00088 20.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 CBK21495.2 - 0.00057 19.1 1.0 0.075 12.2 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.7 CBK21495.2 - 0.00088 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBK21495.2 - 0.001 18.5 0.2 0.042 13.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK21495.2 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK21495.2 - 0.0017 18.2 0.0 0.0051 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CBK21495.2 - 0.0029 16.7 0.0 0.011 14.8 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CBK21495.2 - 0.0044 17.3 0.2 0.013 15.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBK21495.2 - 0.01 15.0 0.2 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBK21495.2 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBK21495.2 - 0.015 14.8 0.0 0.058 12.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CBK21495.2 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK21495.2 - 0.025 14.8 0.4 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 CBK21495.2 - 0.026 13.6 0.1 0.067 12.2 0.1 1.7 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 CBK21495.2 - 0.034 14.2 0.0 0.097 12.7 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 CBK21495.2 - 0.057 12.3 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CBK21495.2 - 0.074 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Peptidase_M50B PF13398.1 CBK21495.2 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like NTPase_1 PF03266.10 CBK21495.2 - 0.094 12.4 0.2 0.53 9.9 0.0 2.3 1 1 1 2 2 2 0 NTPase Parvo_NS1 PF01057.12 CBK21495.2 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CBK21495.2 - 0.11 11.2 0.1 1.8 7.3 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain EF1_GNE PF00736.14 CBK21496.2 - 3.3e-25 87.5 0.3 7.6e-25 86.4 0.2 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CBK21496.2 - 9.7e-06 25.6 12.9 9.7e-06 25.6 8.9 3.2 2 0 0 2 2 1 1 Eukaryotic elongation factor 1 beta central acidic region Cnd2 PF05786.9 CBK21496.2 - 4.7e-05 22.1 9.7 6.4e-05 21.6 6.7 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Cwf_Cwc_15 PF04889.7 CBK21496.2 - 0.0061 16.2 4.9 0.0087 15.7 3.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein HBS1_N PF08938.5 CBK21496.2 - 0.013 15.5 3.9 0.67 10.1 0.1 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Sigma70_ner PF04546.8 CBK21496.2 - 0.05 13.2 13.6 0.084 12.4 9.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region IFT43 PF15305.1 CBK21496.2 - 0.069 13.1 5.6 0.11 12.4 3.9 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 DUF1510 PF07423.6 CBK21496.2 - 0.11 11.9 7.5 0.15 11.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GOLD_2 PF13897.1 CBK21496.2 - 0.12 12.5 3.8 0.26 11.5 2.6 1.6 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Spore_coat_CotO PF14153.1 CBK21496.2 - 0.29 10.5 6.8 0.43 10.0 4.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PBP1_TM PF14812.1 CBK21496.2 - 0.34 11.2 5.9 0.68 10.2 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 CBK21496.2 - 0.35 8.7 12.6 0.46 8.3 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.6 CBK21496.2 - 0.55 9.3 7.2 0.93 8.5 5.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TRAP_alpha PF03896.11 CBK21496.2 - 0.98 8.3 5.8 1.9 7.4 4.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 CBK21496.2 - 1.1 7.2 5.4 1.4 6.8 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CBK21496.2 - 5.3 5.3 12.7 6.8 5.0 8.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF3381 PF11861.3 CBK21496.2 - 6.8 6.1 16.1 14 5.1 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Pox_Ag35 PF03286.9 CBK21496.2 - 7.1 6.1 11.3 12 5.3 7.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.20 CBK21498.2 - 6.5e-53 179.5 0.0 8.1e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21498.2 - 4.5e-44 150.4 0.0 5.6e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBK21498.2 - 0.00042 19.7 0.0 0.18 11.1 0.0 2.4 3 0 0 3 3 3 2 RIO1 family APH PF01636.18 CBK21498.2 - 0.004 16.9 0.0 0.0097 15.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK21498.2 - 0.018 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBK21498.2 - 0.036 12.8 0.0 0.054 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBK21498.2 - 0.042 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynein_light PF01221.13 CBK21499.2 - 2.2e-27 94.8 0.2 2.4e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C1 PF00112.18 CBK21500.2 - 1.3e-12 48.0 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK21500.2 - 0.067 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) V-SNARE_C PF12352.3 CBK21501.2 - 1.4e-05 25.0 3.2 4.3e-05 23.5 2.0 1.8 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBK21501.2 - 2.5e-05 23.9 0.8 3.3e-05 23.4 0.6 1.3 1 0 0 1 1 1 1 Sec20 DUF912 PF06024.7 CBK21501.2 - 0.0032 17.4 0.2 0.0045 17.0 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0118 PF01594.11 CBK21501.2 - 0.0047 15.9 0.5 0.0048 15.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 Prominin PF05478.6 CBK21501.2 - 0.04 11.4 0.4 0.047 11.2 0.3 1.0 1 0 0 1 1 1 0 Prominin DUF3592 PF12158.3 CBK21501.2 - 0.066 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Chordopox_A13L PF05961.6 CBK21501.2 - 0.094 12.6 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein OppC_N PF12911.2 CBK21501.2 - 0.1 12.0 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Synaptobrevin PF00957.16 CBK21501.2 - 0.14 11.7 4.6 0.29 10.7 3.2 1.6 1 1 0 1 1 1 0 Synaptobrevin TarH PF02203.10 CBK21501.2 - 3.2 7.5 5.5 18 5.0 0.1 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue Pkinase PF00069.20 CBK21502.2 - 8.7e-38 129.9 0.0 8.7e-38 129.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21502.2 - 4.2e-20 71.9 0.0 4.2e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK21502.2 - 9.4e-06 25.5 0.0 0.00051 19.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK21502.2 - 0.0022 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBK21502.2 - 0.006 15.4 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RRM_1 PF00076.17 CBK21504.2 - 1.5e-42 143.0 0.2 3.6e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21504.2 - 1.7e-30 104.8 0.0 7.1e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21504.2 - 4.5e-21 74.4 0.4 6.2e-10 38.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK21504.2 - 0.00014 21.5 0.0 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CBK21504.2 - 0.0015 18.2 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBK21504.2 - 5.5 6.8 14.6 0.17 11.6 0.2 3.6 3 1 0 3 3 3 0 Limkain b1 PHD PF00628.24 CBK21505.2 - 2.3e-10 39.9 5.2 2.9e-10 39.6 3.6 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBK21505.2 - 0.0023 18.0 3.4 0.003 17.6 2.3 1.3 1 1 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CBK21505.2 - 0.0044 16.3 2.0 0.0071 15.6 1.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBK21505.2 - 0.027 14.4 1.5 0.027 14.4 1.0 1.3 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 CBK21505.2 - 0.1 12.6 2.9 0.21 11.6 2.0 1.5 1 1 0 1 1 1 0 RING-like domain zf-MIZ PF02891.15 CBK21505.2 - 0.52 9.8 3.1 1.5 8.3 2.2 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Sec8_exocyst PF04048.9 CBK21506.2 - 2.6e-11 43.3 0.5 4.3e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CBK21506.2 - 9.5e-08 31.2 3.7 1.2e-07 30.9 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CBK21506.2 - 0.0046 16.8 0.7 0.0081 16.0 0.5 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2366 PF10171.4 CBK21506.2 - 0.067 12.6 0.6 0.15 11.4 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2366) DEAD PF00270.24 CBK21507.2 - 7.1e-43 146.0 0.0 4.1e-41 140.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21507.2 - 1.4e-27 95.3 0.0 1.4e-26 92.1 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBK21507.2 - 0.015 14.3 0.1 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 CBK21507.2 - 0.029 12.7 0.0 0.14 10.5 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) PP2C PF00481.16 CBK21508.2 - 4.6e-69 232.6 0.0 5.7e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBK21508.2 - 2e-09 37.1 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SPRY PF00622.23 CBK21510.2 - 5e-07 29.8 0.1 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 2 SPRY domain HECT PF00632.20 CBK21511.2 - 1.5e-39 136.0 0.0 3.6e-36 124.9 0.0 2.6 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBK21511.2 - 4e-10 39.8 0.8 9.6e-10 38.6 0.6 1.6 1 0 0 1 1 1 1 SPRY domain TPR_11 PF13414.1 CBK21512.2 - 3e-16 58.7 2.8 3.5e-12 45.7 0.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBK21512.2 - 1.7e-15 55.6 1.4 0.00029 20.5 0.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21512.2 - 2e-11 42.9 3.9 2.4e-05 23.7 0.3 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21512.2 - 2.4e-06 27.6 0.0 0.69 10.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK21512.2 - 5.3e-06 26.2 4.6 0.048 13.5 0.2 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21512.2 - 9.3e-06 26.1 0.7 0.34 11.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21512.2 - 3.9e-05 23.9 0.2 0.038 14.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBK21512.2 - 0.00012 22.1 7.7 0.013 15.6 1.5 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBK21512.2 - 0.00054 19.5 0.5 1.7 8.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.15 CBK21512.2 - 0.00066 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin TPR_8 PF13181.1 CBK21512.2 - 0.0012 18.4 2.8 4.6 7.2 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK21512.2 - 0.0018 18.1 0.5 0.027 14.2 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK21512.2 - 0.0045 17.0 7.0 0.17 12.1 0.3 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBK21512.2 - 0.018 14.9 1.3 0.25 11.3 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_8 PF13905.1 CBK21512.2 - 0.03 14.4 0.5 0.73 9.9 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like Coatomer_E PF04733.9 CBK21512.2 - 0.063 12.4 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit SHNi-TPR PF10516.4 CBK21512.2 - 0.067 12.4 0.1 0.39 9.9 0.1 2.1 2 0 0 2 2 2 0 SHNi-TPR DUF1028 PF06267.7 CBK21512.2 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF1028) TPR_6 PF13174.1 CBK21512.2 - 0.82 10.2 3.6 12 6.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBK21512.2 - 1.2 8.9 5.4 6.8 6.5 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBK21513.2 - 4.5e-10 39.1 0.0 4.8e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBK21513.2 - 0.00023 21.3 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Myosin_tail_1 PF01576.14 CBK21514.2 - 0.00049 17.9 32.1 0.0011 16.7 22.2 1.5 1 1 0 1 1 1 1 Myosin tail Filament PF00038.16 CBK21514.2 - 0.0012 18.3 22.9 0.003 17.0 10.9 2.1 1 1 1 2 2 2 1 Intermediate filament protein IncA PF04156.9 CBK21514.2 - 0.0056 16.3 25.0 0.14 11.7 17.6 2.0 1 1 0 1 1 1 1 IncA protein FlxA PF14282.1 CBK21514.2 - 0.012 15.5 18.8 0.016 15.1 12.2 1.8 1 1 1 2 2 2 0 FlxA-like protein Syntaxin-6_N PF09177.6 CBK21514.2 - 0.014 15.7 15.2 0.44 10.9 2.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2732 PF10809.3 CBK21514.2 - 0.018 14.5 9.4 0.026 14.0 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2732) HOOK PF05622.7 CBK21514.2 - 0.043 11.6 18.0 0.055 11.2 12.5 1.1 1 0 0 1 1 1 0 HOOK protein CENP-F_leu_zip PF10473.4 CBK21514.2 - 0.044 13.6 26.4 0.086 12.6 6.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 CBK21514.2 - 0.052 13.5 21.2 0.1 12.5 14.7 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pox_A_type_inc PF04508.7 CBK21514.2 - 0.071 12.9 12.8 0.18 11.6 0.2 4.8 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat GAS PF13851.1 CBK21514.2 - 0.076 12.2 22.5 0.1 11.7 15.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3573 PF12097.3 CBK21514.2 - 0.076 11.6 1.3 0.097 11.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) MAD PF05557.8 CBK21514.2 - 0.084 10.9 20.8 0.11 10.6 14.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein COG5 PF10392.4 CBK21514.2 - 0.091 12.7 4.6 0.13 12.2 1.4 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3829 PF12889.2 CBK21514.2 - 0.11 11.6 10.4 0.14 11.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF948 PF06103.6 CBK21514.2 - 0.13 12.1 6.7 2.4 8.0 2.3 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 CBK21514.2 - 0.18 11.4 25.8 0.79 9.3 12.1 2.1 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 CBK21514.2 - 0.22 11.9 16.6 2.8 8.3 11.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 CBK21514.2 - 0.27 11.0 2.9 0.6 9.9 1.8 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 CBK21514.2 - 0.36 10.7 24.4 0.081 12.8 10.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mitofilin PF09731.4 CBK21514.2 - 0.38 9.3 19.0 0.47 9.0 13.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.6 CBK21514.2 - 0.46 10.3 18.3 0.63 9.8 12.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PspA_IM30 PF04012.7 CBK21514.2 - 0.48 9.7 27.1 2.8 7.2 5.5 2.2 1 1 1 2 2 2 0 PspA/IM30 family DUF3584 PF12128.3 CBK21514.2 - 0.49 7.6 23.8 0.59 7.3 16.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 CBK21514.2 - 0.53 10.0 24.5 38 4.0 17.0 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 CBK21514.2 - 0.59 9.8 18.2 0.52 10.0 4.0 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4200 PF13863.1 CBK21514.2 - 0.81 9.6 30.6 0.99 9.3 8.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) APG6 PF04111.7 CBK21514.2 - 1 8.3 28.1 0.4 9.6 7.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CBK21514.2 - 1.3 8.8 11.7 0.83 9.4 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 CBK21514.2 - 1.4 8.3 24.3 1.1 8.6 5.8 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 Apt1 PF10351.4 CBK21514.2 - 1.6 7.4 13.4 3 6.6 9.3 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF4140 PF13600.1 CBK21514.2 - 1.7 9.1 19.5 8.6 6.8 3.3 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 CBK21514.2 - 1.8 8.8 8.1 3 8.1 4.0 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TROVE PF05731.6 CBK21514.2 - 2.4 6.8 12.0 2.5 6.7 7.3 1.6 1 1 1 2 2 2 0 TROVE domain MCPVI PF02993.9 CBK21514.2 - 2.5 8.1 5.6 3.4 7.7 3.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI AAA_13 PF13166.1 CBK21514.2 - 2.9 6.2 20.2 7.4 4.8 14.0 1.5 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 CBK21514.2 - 3.3 7.2 20.4 2 7.9 10.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NUDE_C PF04880.8 CBK21514.2 - 3.5 7.9 13.7 0.77 10.0 2.8 2.2 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region ERM PF00769.14 CBK21514.2 - 4.3 6.7 31.5 1.2 8.6 5.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Med9 PF07544.8 CBK21514.2 - 4.6 7.0 25.5 1.9 8.3 3.0 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 CBK21514.2 - 5.1 6.8 27.9 4.3 7.1 6.9 3.3 1 1 0 2 2 2 0 Prefoldin subunit Herpes_UL25 PF01499.11 CBK21514.2 - 5.3 5.2 9.4 6.3 4.9 6.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Cob_adeno_trans PF01923.13 CBK21514.2 - 5.4 6.7 11.3 30 4.3 7.1 2.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase TMF_DNA_bd PF12329.3 CBK21514.2 - 5.9 6.7 29.7 6.1 6.7 0.3 3.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBK21514.2 - 6.3 5.9 17.0 8.4 5.5 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.8 CBK21514.2 - 6.4 6.1 9.4 2.6 7.3 3.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region CENP-H PF05837.7 CBK21514.2 - 6.6 6.9 19.0 11 6.2 8.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BBP1_C PF15272.1 CBK21514.2 - 7.2 6.1 17.2 8.5 5.8 9.9 1.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Spc7 PF08317.6 CBK21514.2 - 7.3 5.1 24.5 1.6 7.3 9.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1479 PF07350.7 CBK21514.2 - 7.4 4.9 11.0 17 3.7 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1479) PilJ PF13675.1 CBK21514.2 - 8.1 6.7 9.4 42 4.4 4.8 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term UPF0242 PF06785.6 CBK21514.2 - 8.4 4.9 15.0 11 4.5 10.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) EAP30 PF04157.11 CBK21514.2 - 9.5 5.3 13.2 2.8 7.0 0.5 2.2 1 1 1 2 2 2 0 EAP30/Vps36 family zf-CCCH_2 PF14608.1 CBK21515.2 - 0.00017 21.4 24.4 0.13 12.3 5.7 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CBK21515.2 - 0.0021 17.6 20.2 0.0023 17.5 2.9 3.6 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HSP70 PF00012.15 CBK21516.2 - 1.3e-74 251.2 0.0 2.1e-74 250.5 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK21516.2 - 9.4e-14 50.7 0.0 8.7e-13 47.5 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK21516.2 - 7.5e-08 32.2 1.9 0.0044 16.8 0.2 3.7 4 0 0 4 4 4 2 Cell division protein FtsA DEDD_Tnp_IS110 PF01548.12 CBK21516.2 - 0.0065 16.1 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Transposase DDR PF08841.5 CBK21516.2 - 0.013 14.3 0.1 1.8 7.3 0.0 2.7 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBK21516.2 - 0.019 13.9 0.0 0.043 12.7 0.0 1.6 1 0 0 1 1 1 0 StbA protein UPF0184 PF03670.8 CBK21516.2 - 0.16 12.1 1.1 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) TRAP_alpha PF03896.11 CBK21517.2 - 3.2e-11 42.7 1.3 3.7e-11 42.5 0.9 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Peptidase_C50 PF03568.12 CBK21518.2 - 8.7e-25 87.1 5.1 3.5e-08 32.5 0.1 4.2 4 0 0 4 4 4 4 Peptidase family C50 DUF4028 PF13220.1 CBK21518.2 - 0.21 11.2 2.0 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) RAP1 PF07218.6 CBK21518.2 - 2.6 6.0 4.5 3.8 5.5 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2 PF00096.21 CBK21519.2 - 6.7e-11 41.8 25.3 7.3e-05 22.8 0.8 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK21519.2 - 9.9e-09 34.9 25.0 0.0019 18.3 0.4 5.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK21519.2 - 5e-06 26.5 30.7 3e-05 24.0 1.6 6.7 7 1 0 7 7 7 3 Zinc-finger double domain DUF2197 PF09963.4 CBK21519.2 - 0.025 14.5 0.7 0.068 13.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) YppF PF14178.1 CBK21519.2 - 0.035 13.6 0.4 0.085 12.4 0.3 1.7 1 0 0 1 1 1 0 YppF-like protein zf-C2H2_6 PF13912.1 CBK21519.2 - 0.046 13.6 0.2 0.046 13.6 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBK21519.2 - 0.075 13.1 0.0 0.075 13.1 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 CBK21519.2 - 0.14 12.3 2.0 0.26 11.4 0.2 2.4 2 0 0 2 2 2 0 CHY zinc finger DivIC PF04977.10 CBK21519.2 - 4.6 6.7 7.6 0.94 9.0 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator zf-C2HC PF01530.13 CBK21519.2 - 9.1 6.1 6.9 22 4.8 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2HC type Glucosamine_iso PF01182.15 CBK21520.2 - 0.0053 16.4 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Med26 PF08711.6 CBK21521.2 - 1.2e-07 31.1 0.7 2e-07 30.3 0.5 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HSP70 PF00012.15 CBK21522.2 - 1.3e-150 502.2 12.4 4e-118 394.9 0.5 2.9 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK21522.2 - 5.6e-14 51.4 0.8 5.2e-12 45.0 0.2 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBK21522.2 - 1.2e-05 25.1 4.1 0.12 12.2 0.1 3.5 3 0 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 CBK21522.2 - 0.0072 15.4 0.2 0.029 13.4 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF2805 PF10985.3 CBK21522.2 - 0.33 10.9 3.9 0.2 11.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Ribosomal_60s PF00428.14 CBK21523.2 - 5.1e-18 65.2 8.3 6.8e-18 64.8 5.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Myc_N PF01056.13 CBK21523.2 - 0.045 12.9 0.3 0.056 12.5 0.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Shadoo PF14999.1 CBK21523.2 - 2.5 7.9 6.9 3.1 7.6 4.4 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective SpoIIE PF07228.7 CBK21524.2 - 7.3e-05 22.5 0.0 0.00026 20.7 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBK21524.2 - 0.00062 19.2 0.1 0.002 17.5 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.17 CBK21525.2 - 1.6e-52 177.1 1.1 2.3e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK21525.2 - 1.8e-15 57.4 0.2 8.5e-15 55.2 0.1 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK21525.2 - 1.3e-12 47.2 0.1 1.8e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK21525.2 - 6.7e-06 25.6 0.2 2.3e-05 23.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBK21525.2 - 9e-05 21.7 0.5 0.00017 20.7 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK21525.2 - 0.00075 19.4 0.1 0.0018 18.2 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK21525.2 - 0.0028 16.9 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CBK21525.2 - 0.0029 17.1 0.1 0.014 14.9 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CBK21525.2 - 0.0046 16.5 0.5 0.0064 16.0 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK21525.2 - 0.024 14.7 0.0 0.43 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Methyltransf_27 PF13708.1 CBK21525.2 - 0.026 14.0 0.2 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_5 PF07728.9 CBK21525.2 - 0.027 14.2 0.0 0.066 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CBK21525.2 - 0.047 12.8 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CBK21525.2 - 0.075 12.3 0.1 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B BRCT PF00533.21 CBK21526.2 - 2.8e-09 37.0 0.0 1.1e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.13 CBK21526.2 - 1.7e-05 23.8 6.5 3.2e-05 22.9 4.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PTCB-BRCT PF12738.2 CBK21526.2 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Nop14 PF04147.7 CBK21526.2 - 0.011 13.7 18.7 0.014 13.3 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 CBK21526.2 - 0.098 10.3 13.9 0.13 9.9 9.6 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 CBK21526.2 - 0.1 10.8 16.8 0.16 10.2 11.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.11 CBK21526.2 - 0.75 8.3 2.5 0.99 7.9 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3c_N PF05470.7 CBK21526.2 - 0.94 7.4 14.9 1.4 6.9 10.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RR_TM4-6 PF06459.7 CBK21526.2 - 1.2 8.9 19.4 1.8 8.4 13.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RabGAP-TBC PF00566.13 CBK21526.2 - 3.1 7.2 6.3 4.4 6.7 3.8 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Afi1 PF07792.7 CBK21526.2 - 3.5 7.6 11.3 6.9 6.6 7.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.9 CBK21526.2 - 7.1 4.5 15.9 10 4.0 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 CBK21526.2 - 7.5 4.6 16.1 12 3.9 11.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF3513 PF12026.3 CBK21526.2 - 9.6 5.6 12.4 16 4.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) HSP90 PF00183.13 CBK21526.2 - 10 4.4 25.2 15 3.8 17.5 1.2 1 0 0 1 1 1 0 Hsp90 protein MFS_1 PF07690.11 CBK21527.2 - 4.4e-32 111.1 32.3 4.4e-25 88.1 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBK21527.2 - 2.9e-06 25.9 11.6 2.9e-06 25.9 8.0 3.0 1 1 2 3 3 3 1 MFS/sugar transport protein DUF788 PF05620.6 CBK21527.2 - 0.39 10.5 0.0 0.39 10.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Peptidase_C13 PF01650.13 CBK21528.2 - 3.2e-43 147.8 0.0 4e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family zf-B_box PF00643.19 CBK21529.2 - 0.0043 16.9 4.7 0.0043 16.9 3.3 2.0 2 0 0 2 2 2 1 B-box zinc finger IBD PF10416.4 CBK21529.2 - 0.013 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Myb_DNA-binding PF00249.26 CBK21529.2 - 0.018 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain FYVE PF01363.16 CBK21529.2 - 0.19 11.6 8.9 0.49 10.3 6.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.17 CBK21529.2 - 1 9.1 8.1 1.7 8.4 5.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tnp_zf-ribbon_2 PF13842.1 CBK21529.2 - 1.5 9.3 9.6 4.2 7.8 6.7 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-RING_5 PF14634.1 CBK21529.2 - 2.1 8.1 12.7 0.53 10.0 6.0 2.2 3 0 0 3 3 3 0 zinc-RING finger domain SWIRM PF04433.12 CBK21530.2 - 7.5e-06 25.9 0.0 3.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 SWIRM domain Ion_trans PF00520.26 CBK21531.2 - 0.0015 17.8 0.4 0.0017 17.6 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein DUF3671 PF12420.3 CBK21531.2 - 0.0076 16.2 0.9 0.01 15.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function Cytochrom_B_C PF00032.12 CBK21531.2 - 0.011 16.0 1.9 0.013 15.7 1.3 1.1 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF2207 PF09972.4 CBK21531.2 - 0.018 13.6 0.2 0.02 13.4 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF843 PF05814.6 CBK21531.2 - 0.018 14.8 6.8 0.031 14.0 4.7 1.5 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) MARVEL PF01284.18 CBK21531.2 - 0.075 12.8 1.4 0.095 12.5 1.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain KASH PF10541.4 CBK21531.2 - 0.084 12.7 0.9 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF3278 PF11683.3 CBK21531.2 - 0.59 10.1 5.2 0.76 9.7 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF3043 PF11241.3 CBK21531.2 - 1.4 8.4 3.5 2.3 7.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF912 PF06024.7 CBK21531.2 - 2.1 8.4 7.9 7.9 6.5 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spt5-NGN PF03439.8 CBK21532.2 - 0.00024 20.8 0.5 0.0023 17.6 0.0 2.4 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section ICMT PF04140.9 CBK21532.2 - 0.054 13.6 0.2 0.099 12.8 0.2 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 7TM_GPCR_Str PF10326.4 CBK21533.2 - 0.037 13.1 0.4 0.047 12.8 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF3609 PF12259.3 CBK21533.2 - 0.047 12.3 0.1 0.056 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) SP_C-Propep PF08999.5 CBK21533.2 - 0.23 10.9 2.5 0.45 10.0 1.7 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.1 CBK21533.2 - 1.6 9.1 5.7 3.9 7.9 4.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RRM_1 PF00076.17 CBK21535.2 - 1e-06 28.2 0.0 0.005 16.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21535.2 - 0.00031 20.6 0.0 0.0007 19.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F_bP_aldolase PF01116.15 CBK21536.2 - 2.4e-88 295.9 0.0 2.8e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.1 CBK21536.2 - 0.11 12.4 0.3 0.89 9.5 0.1 2.3 2 0 0 2 2 2 0 Enolase C-terminal domain-like HAD_2 PF13419.1 CBK21537.2 - 4.1e-16 59.7 0.0 5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBK21537.2 - 1.2e-09 37.7 0.0 2.4e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 CBK21537.2 - 0.025 14.9 0.0 0.034 14.5 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF59 PF01883.14 CBK21538.2 - 0.015 15.2 0.1 0.035 14.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF59 ATG16 PF08614.6 CBK21539.2 - 0.0011 18.8 8.6 0.0011 18.8 6.0 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 CBK21539.2 - 0.061 13.0 17.3 0.051 13.2 6.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Thioredoxin PF00085.15 CBK21540.2 - 1.2e-25 89.1 0.1 2.8e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBK21540.2 - 3.5e-05 23.6 0.0 0.038 13.8 0.0 2.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK21540.2 - 0.00031 20.9 2.4 0.1 12.7 0.2 3.4 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK21540.2 - 0.009 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK21540.2 - 0.024 14.7 0.1 1.7 8.8 0.1 2.6 1 1 1 2 2 2 0 Thioredoxin-like PsbN PF02468.10 CBK21540.2 - 0.083 12.5 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Peptidase_M48 PF01435.13 CBK21541.2 - 5.9e-13 48.9 0.3 1.4e-11 44.3 0.2 2.3 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 CBK21541.2 - 0.0082 15.3 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M13 Rubrerythrin PF02915.12 CBK21541.2 - 0.064 13.5 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 Rubrerythrin DUF45 PF01863.12 CBK21541.2 - 0.14 11.9 0.5 0.37 10.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function DUF45 GOLD_2 PF13897.1 CBK21542.2 - 0.0067 16.6 2.3 0.034 14.3 0.0 2.6 2 1 1 3 3 3 1 Golgi-dynamics membrane-trafficking zf-SNAP50_C PF12251.3 CBK21542.2 - 0.026 13.8 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal FCH PF00611.18 CBK21542.2 - 0.057 13.6 1.1 0.11 12.6 0.7 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain F-box-like PF12937.2 CBK21542.2 - 0.1 12.3 0.4 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 F-box-like DivIC PF04977.10 CBK21542.2 - 0.79 9.2 4.9 1.7 8.1 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator DEAD PF00270.24 CBK21543.2 - 7.3e-48 162.2 0.1 3.2e-47 160.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21543.2 - 2.7e-26 91.2 0.2 2.9e-25 87.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21543.2 - 3e-05 23.9 0.0 3e-05 23.9 0.0 4.2 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBK21543.2 - 0.0046 17.1 2.0 0.0087 16.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBK21543.2 - 0.033 13.9 1.6 0.056 13.2 0.2 2.1 2 0 0 2 2 2 0 Part of AAA domain DUF3573 PF12097.3 CBK21543.2 - 0.069 11.7 4.8 0.11 11.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1162 PF06650.7 CBK21544.2 - 2.7e-24 85.8 0.1 7.6e-22 77.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) UCH PF00443.24 CBK21545.2 - 5.3e-22 78.1 0.0 4.2e-21 75.2 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21545.2 - 0.00036 20.0 6.1 0.0005 19.5 0.1 3.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Glycos_transf_2 PF00535.21 CBK21546.2 - 1.9e-18 66.7 0.0 3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBK21546.2 - 3.3e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBK21546.2 - 1.5e-05 24.2 0.0 2.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBK21546.2 - 0.0027 17.1 0.3 0.0063 15.9 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Ribosomal_S6e PF01092.14 CBK21547.2 - 9.8e-59 196.5 0.3 1.7e-58 195.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e He_PIG PF05345.7 CBK21548.2 - 6.9e-12 45.1 15.8 1.8e-06 27.8 0.1 4.0 4 0 0 4 4 4 3 Putative Ig domain His_Phos_1 PF00300.17 CBK21549.2 - 2.6e-41 141.3 0.0 3.3e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ycf15 PF10705.4 CBK21549.2 - 0.029 14.4 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative BCAS2 PF05700.6 CBK21550.2 - 1.2e-29 103.3 6.8 1.4e-29 103.1 4.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CtIP_N PF10482.4 CBK21550.2 - 0.017 14.9 4.3 0.02 14.6 0.8 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF2003 PF09404.5 CBK21550.2 - 0.025 12.9 0.1 0.029 12.7 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF2003) DSS1_SEM1 PF05160.8 CBK21551.2 - 2.8e-16 59.0 13.7 3.3e-16 58.8 9.5 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 CBK21551.2 - 0.00046 19.8 3.7 0.00046 19.8 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) Aminotran_1_2 PF00155.16 CBK21552.2 - 1.1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK21552.2 - 0.0025 17.0 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase LON PF02190.11 CBK21553.2 - 0.034 13.8 0.0 0.041 13.5 0.0 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF4597 PF15366.1 CBK21553.2 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) VHP PF02209.14 CBK21554.2 - 1.5e-16 59.7 0.5 4e-16 58.3 0.4 1.8 1 0 0 1 1 1 1 Villin headpiece domain LIM PF00412.17 CBK21555.2 - 1.4e-09 37.8 4.1 1.4e-09 37.8 2.8 2.9 2 1 1 3 3 3 1 LIM domain DUF2685 PF10886.3 CBK21555.2 - 0.35 10.9 9.3 0.48 10.4 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2685) XPA_N PF01286.13 CBK21555.2 - 0.46 10.2 0.1 0.46 10.2 0.1 4.4 3 2 1 4 4 4 0 XPA protein N-terminal Rad50_zn_hook PF04423.9 CBK21555.2 - 2.1 7.8 0.0 2.1 7.8 0.0 3.9 2 1 1 4 4 4 0 Rad50 zinc hook motif HNH_5 PF14279.1 CBK21555.2 - 3.1 7.8 10.1 0.13 12.3 0.9 2.4 2 1 0 2 2 2 0 HNH endonuclease Pkinase PF00069.20 CBK21556.2 - 1.4e-37 129.3 0.0 1.6e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21556.2 - 6e-23 81.2 0.0 6.4e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21556.2 - 0.0018 17.2 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK21556.2 - 0.027 14.2 0.5 0.038 13.7 0.3 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CBK21556.2 - 0.15 11.3 0.1 0.21 10.8 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Peptidase_M49 PF03571.10 CBK21558.2 - 2.1e-182 607.0 0.0 2.6e-182 606.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SHS2_Rpb7-N PF03876.12 CBK21559.2 - 2.8e-13 49.8 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Atx10homo_assoc PF09759.4 CBK21561.2 - 4.7e-25 87.2 0.3 3.1e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF498 PF04430.9 CBK21562.2 - 1.6e-24 85.5 0.0 1.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF1900 PF08954.6 CBK21563.2 - 1.2e-48 164.1 0.0 1.9e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CBK21563.2 - 3.8e-12 45.6 0.1 4.2e-06 26.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.6 CBK21564.2 - 8.4e-13 47.7 0.0 9.6e-13 47.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) tRNA_Me_trans PF03054.11 CBK21565.2 - 1.7e-104 349.1 0.0 2.2e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 CBK21565.2 - 1.4e-06 27.9 0.0 4.5e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 CBK21565.2 - 2.3e-06 26.7 0.0 9e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 CBK21565.2 - 0.00026 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CBK21565.2 - 0.03 13.6 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 CBK21565.2 - 0.04 13.4 0.1 9.4 5.6 0.0 2.3 2 0 0 2 2 2 0 PP-loop family Lung_7-TM_R PF06814.8 CBK21566.2 - 4.5e-29 101.3 22.1 5.8e-29 100.9 15.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBK21566.2 - 0.00044 19.5 22.8 0.00044 19.5 15.8 1.5 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain HD PF01966.17 CBK21567.2 - 0.00056 19.9 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 CBK21567.2 - 0.024 13.9 0.1 0.063 12.5 0.1 1.6 1 1 0 1 1 1 0 HDOD domain Peptidase_M14 PF00246.19 CBK21569.2 - 1.3e-11 44.6 0.0 8.2e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Zinc carboxypeptidase AstE_AspA PF04952.9 CBK21569.2 - 0.035 12.9 0.0 3 6.6 0.0 2.1 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Ribosomal_S28e PF01200.13 CBK21570.2 - 4.5e-29 99.9 1.8 4.8e-29 99.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ABC1 PF03109.11 CBK21571.2 - 3.4e-28 97.9 0.0 5.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CBK21571.2 - 0.0011 18.7 0.0 0.31 10.7 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 CBK21571.2 - 0.0022 17.1 0.0 0.059 12.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 CBK21571.2 - 0.0076 15.0 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Dynactin_p62 PF05502.8 CBK21572.2 - 7.7e-14 51.3 31.7 3.7e-12 45.7 17.1 2.1 1 1 1 2 2 2 2 Dynactin p62 family Imm21 PF15569.1 CBK21573.2 - 0.47 10.2 2.5 0.62 9.8 1.7 1.2 1 0 0 1 1 1 0 Immunity protein 21 UDPGP PF01704.13 CBK21574.2 - 3.2e-09 35.7 0.0 4.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF624 PF04854.9 CBK21575.2 - 0.079 12.8 0.2 0.079 12.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 ASFV_J13L PF05568.6 CBK21576.2 - 0.026 14.0 0.8 0.045 13.3 0.6 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2868 PF11067.3 CBK21576.2 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TMEM154 PF15102.1 CBK21576.2 - 0.14 11.8 1.6 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF4006 PF13179.1 CBK21576.2 - 0.26 10.8 4.2 0.72 9.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) EphA2_TM PF14575.1 CBK21576.2 - 2.2 8.7 4.4 1.7 9.1 0.8 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 CBK21576.2 - 2.9 7.3 7.7 0.99 8.8 0.9 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family MMS19_C PF12460.3 CBK21577.2 - 0.019 13.7 1.0 0.022 13.5 0.7 1.0 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DUF1237 PF06824.6 CBK21578.2 - 6.4e-156 519.2 0.0 7.4e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) PT PF04886.7 CBK21579.2 - 0.0024 17.1 5.1 0.0024 17.1 3.5 3.0 3 0 0 3 3 3 1 PT repeat DUF948 PF06103.6 CBK21579.2 - 0.15 11.9 0.5 0.71 9.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PIP5K PF01504.13 CBK21580.2 - 7.2e-57 192.3 0.6 1.4e-56 191.4 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1199 PF06712.6 CBK21580.2 - 0.074 12.8 0.1 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Cpn60_TCP1 PF00118.19 CBK21581.2 - 5.5e-08 31.8 0.2 5.9e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 CBK21582.2 - 1.4e-07 30.5 0.0 1.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CBK21583.2 - 6.9e-14 51.4 11.0 7.3e-14 51.4 7.6 1.0 1 0 0 1 1 1 1 FYVE zinc finger C1_4 PF07975.7 CBK21583.2 - 0.0011 18.9 10.7 0.0015 18.4 7.4 1.3 1 0 0 1 1 1 1 TFIIH C1-like domain MU117 PF15474.1 CBK21583.2 - 0.1 13.1 4.0 0.13 12.7 2.8 1.2 1 0 0 1 1 1 0 Meiotically up-regulated gene family zf-RING_2 PF13639.1 CBK21583.2 - 1.1 9.2 11.7 1.3 8.8 8.1 1.3 1 0 0 1 1 1 0 Ring finger domain FYVE_2 PF02318.11 CBK21583.2 - 1.1 9.1 9.9 1.3 8.9 6.8 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.5 CBK21583.2 - 6.2 6.8 9.8 21 5.1 3.0 2.8 1 1 1 2 2 2 0 Zinc ribbon domain IBR PF01485.16 CBK21583.2 - 6.9 6.6 14.7 15 5.5 10.2 1.5 1 1 0 1 1 1 0 IBR domain ER_lumen_recept PF00810.13 CBK21584.2 - 6.2e-45 153.2 10.9 6.2e-45 153.2 7.6 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBK21584.2 - 0.009 15.5 16.4 0.046 13.2 0.5 3.9 4 0 0 4 4 4 2 PQ loop repeat zf-DHHC PF01529.15 CBK21585.2 - 3e-35 121.1 8.8 3e-35 121.1 6.1 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.8 CBK21585.2 - 7.7 6.1 8.4 0.93 9.0 0.3 2.7 3 0 0 3 3 3 0 HemY protein N-terminus Mito_carr PF00153.22 CBK21586.2 - 6.2e-69 227.7 2.3 1.6e-28 98.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PhoU PF01895.14 CBK21587.2 - 1.4 9.4 7.5 4.7 7.7 0.6 2.8 3 1 0 3 3 3 0 PhoU domain SF3b1 PF08920.5 CBK21588.2 - 1.1e-24 87.1 0.5 1.8e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CBK21588.2 - 7e-15 55.0 1.5 0.1 12.8 0.0 7.3 4 2 2 8 8 7 6 HEAT repeats HEAT_EZ PF13513.1 CBK21588.2 - 8e-13 48.4 5.6 0.031 14.7 0.0 8.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.17 CBK21588.2 - 1.6e-11 43.2 16.4 0.023 14.7 0.1 10.5 11 0 0 11 11 11 2 HEAT repeat Adaptin_N PF01602.15 CBK21588.2 - 2.5e-07 29.4 2.9 0.0058 15.0 0.0 3.6 3 1 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 CBK21588.2 - 5.4e-05 22.8 13.4 1.4 8.8 0.0 7.7 10 0 0 10 10 10 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CBK21588.2 - 0.00016 21.0 0.6 4.9 6.4 0.0 4.6 4 1 1 5 5 5 2 CLASP N terminal NUC173 PF08161.7 CBK21588.2 - 0.0012 18.2 0.4 3 7.1 0.0 4.9 5 1 0 5 5 5 1 NUC173 domain Proteasom_PSMB PF10508.4 CBK21588.2 - 0.022 13.0 0.1 3.5 5.7 0.1 3.1 1 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.2 CBK21588.2 - 0.067 13.5 3.0 39 4.7 0.0 4.7 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF4021 PF13213.1 CBK21588.2 - 0.15 11.7 0.2 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4021) CTD PF12815.2 CBK21588.2 - 0.49 10.8 11.1 2.1 8.7 7.7 2.0 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Cnd1 PF12717.2 CBK21588.2 - 2.4 7.9 5.8 47 3.7 0.1 5.0 5 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 LRR_8 PF13855.1 CBK21589.2 - 0.0011 18.6 0.2 0.18 11.5 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat BRCA-2_OB1 PF09103.5 CBK21589.2 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 MORN PF02493.15 CBK21590.2 - 0.00057 19.4 20.6 0.12 12.1 1.1 7.1 7 0 0 7 7 7 4 MORN repeat DYW_deaminase PF14432.1 CBK21590.2 - 0.093 12.7 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases DUF1472 PF07339.7 CBK21591.2 - 0.047 14.0 0.3 0.07 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) ERCC4 PF02732.10 CBK21592.2 - 8.2e-15 54.8 0.0 2.3e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 ERCC4 domain Gtr1_RagA PF04670.7 CBK21595.2 - 7.2e-29 100.5 1.1 8.4e-29 100.3 0.8 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region tRNA-synt_1f PF01921.13 CBK21595.2 - 0.021 13.4 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) XRN_N PF03159.13 CBK21596.2 - 9.2e-80 267.4 0.0 6.5e-79 264.6 0.0 2.0 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Peptidase_M20 PF01546.23 CBK21597.2 - 1.9e-17 63.4 0.0 2.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBK21597.2 - 0.034 13.8 0.1 0.15 11.8 0.1 2.0 1 1 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBK21597.2 - 0.044 13.5 0.1 0.2 11.3 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M28 RhoGAP PF00620.22 CBK21598.2 - 1e-20 73.8 0.0 9.7e-16 57.7 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain Clat_adaptor_s PF01217.15 CBK21599.2 - 1.6e-09 37.5 0.2 1.9e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L18p PF00861.17 CBK21600.2 - 9.1e-42 142.0 0.4 9.1e-42 142.0 0.3 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBK21600.2 - 1.3e-31 109.0 5.9 2.3e-31 108.2 4.1 1.4 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region TPR_12 PF13424.1 CBK21602.2 - 0.00079 19.3 0.2 0.0054 16.6 0.2 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK21602.2 - 0.0016 18.0 0.1 0.0045 16.6 0.0 1.7 1 1 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 CBK21602.2 - 0.0061 17.0 0.3 0.016 15.8 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK21602.2 - 0.0073 16.1 0.0 0.083 12.8 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21602.2 - 0.052 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBK21602.2 - 0.095 12.5 0.1 0.32 10.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaJ_CXXCXGXG PF00684.14 CBK21605.2 - 0.00032 20.6 25.5 0.0012 18.7 16.1 2.6 1 1 1 2 2 2 1 DnaJ central domain DUF3591 PF12157.3 CBK21607.2 - 5.7e-22 77.7 2.3 1.6e-18 66.3 0.0 3.1 3 1 1 4 4 4 2 Protein of unknown function (DUF3591) Bromodomain PF00439.20 CBK21607.2 - 1.9e-10 40.5 0.0 6e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Bromodomain RmlD_sub_bind PF04321.12 CBK21608.2 - 0.044 12.6 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBK21608.2 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DEAD PF00270.24 CBK21609.2 - 3.5e-18 65.6 0.0 6.8e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21609.2 - 1.9e-06 27.6 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK21609.2 - 0.00024 20.9 0.0 0.0041 16.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_8 PF13855.1 CBK21610.2 - 0.0013 18.4 1.4 0.91 9.3 0.3 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBK21610.2 - 0.0092 15.5 0.0 5.4 6.7 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) MORN_2 PF07661.8 CBK21610.2 - 0.77 9.9 4.2 31 5.0 0.1 3.2 2 0 0 2 2 2 0 MORN repeat variant AMP-binding PF00501.23 CBK21611.2 - 1.6e-76 257.3 0.0 2e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AAA_23 PF13476.1 CBK21612.2 - 1.6e-23 84.1 0.1 1.9e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBK21612.2 - 5e-08 32.4 0.1 1.2e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 CBK21612.2 - 1.4e-06 27.7 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK21612.2 - 5.8e-06 26.4 0.1 7.1e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 CBK21612.2 - 3.1e-05 22.6 0.1 5.9e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CBK21612.2 - 3.1e-05 24.2 0.0 5.6e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CBK21612.2 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBK21612.2 - 0.016 15.3 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBK21612.2 - 0.023 13.8 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBK21612.2 - 0.042 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ham1p_like PF01725.11 CBK21612.2 - 0.12 11.7 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 Ham1 family Miro PF08477.8 CBK21612.2 - 0.12 12.8 0.4 0.21 12.0 0.1 1.9 2 1 0 2 2 1 0 Miro-like protein NACHT PF05729.7 CBK21612.2 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 1 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 CBK21613.2 - 4.1e-11 42.6 0.2 1.8e-10 40.6 0.0 2.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBK21613.2 - 1e-07 31.4 0.2 1.3e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 CBK21613.2 - 1.9e-07 30.5 0.2 4.3e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK21613.2 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 CBK21613.2 - 0.013 14.0 0.8 0.02 13.4 0.6 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK21613.2 - 0.047 13.9 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Pfg27 PF09216.5 CBK21614.2 - 0.021 14.4 2.3 0.048 13.2 0.2 2.2 2 0 0 2 2 2 0 Pfg27 HSP90 PF00183.13 CBK21615.2 - 1.4e-238 792.5 31.1 1.9e-238 792.2 21.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CBK21615.2 - 1.1e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK21615.2 - 1.3e-11 44.2 0.1 4.8e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_14 PF13428.1 CBK21616.2 - 0.012 16.2 20.1 0.39 11.4 0.0 7.3 5 2 3 8 8 8 0 Tetratricopeptide repeat Enkurin PF13864.1 CBK21617.2 - 0.013 15.6 9.0 0.017 15.3 6.2 1.1 1 0 0 1 1 1 0 Calmodulin-binding Cas_DxTHG PF09455.5 CBK21617.2 - 0.04 13.0 1.7 0.042 12.9 1.2 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF1967 PF09269.6 CBK21617.2 - 0.059 13.0 0.9 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Adaptin_binding PF10199.4 CBK21617.2 - 0.084 13.1 3.1 0.096 12.9 2.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Uds1 PF15456.1 CBK21617.2 - 0.14 12.1 5.1 0.16 11.9 3.6 1.2 1 0 0 1 1 1 0 Up-regulated During Septation MerR-DNA-bind PF09278.6 CBK21617.2 - 0.24 11.8 3.3 0.52 10.7 2.3 1.6 1 0 0 1 1 1 0 MerR, DNA binding DUF4094 PF13334.1 CBK21617.2 - 0.85 10.0 5.4 26 5.2 3.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) IncA PF04156.9 CBK21617.2 - 1.5 8.3 7.9 2 7.9 5.5 1.1 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 CBK21617.2 - 1.9 8.3 4.2 2.3 8.0 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 CBK21617.2 - 2.3 5.9 6.2 2.6 5.7 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CBK21617.2 - 4.5 6.1 7.6 5.2 5.9 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2721 PF11026.3 CBK21617.2 - 6.1 6.4 6.1 4.4 6.9 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) EzrA PF06160.7 CBK21618.2 - 0.00079 17.7 2.6 0.0011 17.3 1.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA RPW8 PF05659.6 CBK21618.2 - 0.006 16.1 0.8 0.013 15.0 0.6 1.6 1 1 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 MscS_porin PF12795.2 CBK21618.2 - 0.01 15.1 2.7 0.023 14.0 1.9 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 CBK21618.2 - 0.019 14.8 5.0 0.06 13.1 0.6 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pox_G5 PF04599.7 CBK21618.2 - 0.024 13.3 1.8 0.037 12.7 1.3 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein BLOC1_2 PF10046.4 CBK21618.2 - 0.036 14.1 5.3 0.14 12.3 0.2 3.3 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 M-factor PF03855.8 CBK21618.2 - 0.065 13.2 0.5 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 M-factor RAMPs PF03787.10 CBK21618.2 - 0.073 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 RAMP superfamily HeLo PF14479.1 CBK21618.2 - 0.081 12.6 0.9 0.15 11.8 0.5 1.4 1 1 0 1 1 1 0 Prion-inhibition and propagation DNA_topoisoIV PF00521.15 CBK21618.2 - 0.09 11.6 3.8 0.11 11.3 2.6 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A EST1 PF10374.4 CBK21618.2 - 0.13 12.2 2.2 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Telomerase activating protein Est1 TMPIT PF07851.8 CBK21618.2 - 0.29 10.1 2.9 0.25 10.3 0.2 1.8 2 0 0 2 2 2 0 TMPIT-like protein HAUS-augmin3 PF14932.1 CBK21618.2 - 0.46 9.6 9.3 0.047 12.8 1.2 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1319 PF07028.6 CBK21618.2 - 0.62 10.2 4.9 0.56 10.4 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) COG5 PF10392.4 CBK21618.2 - 0.64 9.9 9.6 0.28 11.1 1.5 2.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF1640 PF07798.6 CBK21618.2 - 2 8.4 6.7 11 6.0 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) IncA PF04156.9 CBK21618.2 - 2.4 7.7 9.1 0.56 9.7 3.7 1.8 2 0 0 2 2 2 0 IncA protein V-SNARE PF05008.10 CBK21618.2 - 3 8.0 10.5 1.5 8.9 0.4 3.5 3 2 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus GCN5L1 PF06320.8 CBK21619.2 - 0.041 13.7 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) CHCH PF06747.8 CBK21619.2 - 0.048 13.5 4.3 4.1 7.4 0.4 2.4 2 0 0 2 2 2 0 CHCH domain Glyco_hydro_71 PF03659.9 CBK21620.2 - 7.5e-06 24.6 0.9 2.9e-05 22.7 0.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.1 CBK21620.2 - 0.0011 18.2 11.8 0.0051 16.0 0.8 3.1 2 1 0 2 2 2 1 Glycosyltransferase WbsX DNA_pol_A_exo1 PF01612.15 CBK21621.2 - 1e-19 70.7 0.1 2.1e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CBK21621.2 - 1.4e-08 34.3 0.1 2.6e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 HRDC domain Glycos_transf_1 PF00534.15 CBK21624.2 - 3.2e-13 49.4 0.0 4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBK21624.2 - 9.2e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBK21624.2 - 1.1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 PUF PF00806.14 CBK21625.2 - 4.7e-14 50.9 1.4 0.051 13.0 0.1 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat DUF830 PF05708.7 CBK21625.2 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) Cpn60_TCP1 PF00118.19 CBK21626.2 - 2.1e-133 445.5 1.1 2.1e-133 445.5 0.7 1.4 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family VWA_2 PF13519.1 CBK21626.2 - 0.011 15.8 1.2 0.017 15.2 0.1 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain IF4E PF01652.13 CBK21627.2 - 3.7e-27 94.8 3.0 5.7e-27 94.2 2.1 1.3 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Suf PF05843.9 CBK21628.2 - 5.3e-25 88.7 1.3 2.8e-22 79.7 0.0 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CBK21628.2 - 0.0008 19.7 1.2 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21628.2 - 0.0041 17.6 6.9 2.8 8.8 0.1 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF1360 PF07098.6 CBK21628.2 - 0.084 12.6 1.0 0.23 11.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) TPR_16 PF13432.1 CBK21628.2 - 0.24 12.1 6.1 2.8 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.11 CBK21628.2 - 0.36 10.6 5.0 9 6.1 0.0 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Peptidase_C1 PF00112.18 CBK21629.2 - 2.2e-94 315.4 24.7 1.4e-50 172.2 6.3 2.0 2 0 0 2 2 2 2 Papain family cysteine protease HhH-GPD PF00730.20 CBK21630.2 - 3.2e-18 65.9 0.0 5.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBK21630.2 - 4e-09 35.6 0.7 1.5e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CBK21630.2 - 0.00039 20.4 5.2 0.00039 20.4 3.6 2.0 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III HHH_2 PF12826.2 CBK21630.2 - 0.00052 19.8 0.1 0.98 9.3 0.0 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix motif PDDEXK_1 PF12705.2 CBK21630.2 - 0.016 14.5 2.3 0.11 11.8 1.6 2.1 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HHH_8 PF14716.1 CBK21630.2 - 0.065 13.4 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain YyzF PF14116.1 CBK21630.2 - 0.31 11.0 0.0 0.31 11.0 0.0 2.8 3 0 0 3 3 3 0 YyzF-like protein RseC_MucC PF04246.7 CBK21630.2 - 4.1 6.9 5.3 8.3 5.9 3.7 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Asp_Glu_race PF01177.17 CBK21631.2 - 2.7e-05 24.1 0.0 3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Flavodoxin_1 PF00258.20 CBK21632.2 - 1.5e-21 76.8 0.1 2e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin He_PIG PF05345.7 CBK21633.2 - 8.8e-16 57.6 29.2 4.3e-05 23.4 0.1 5.5 5 1 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK21633.2 - 5.5e-05 22.9 4.9 1.7 8.5 0.1 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.17 CBK21633.2 - 0.00046 20.1 12.5 0.4 10.7 0.1 5.3 5 0 0 5 5 5 2 Hormone receptor domain IncA PF04156.9 CBK21633.2 - 0.021 14.4 0.6 0.031 13.8 0.4 1.2 1 0 0 1 1 1 0 IncA protein PIRT PF15099.1 CBK21633.2 - 0.027 13.7 0.0 0.077 12.2 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4097 PF13349.1 CBK21633.2 - 0.33 10.5 3.6 0.28 10.7 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) hEGF PF12661.2 CBK21633.2 - 0.46 10.6 7.3 11 6.4 0.1 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF PKD PF00801.15 CBK21633.2 - 0.73 9.6 0.0 0.73 9.6 0.0 3.7 5 0 0 5 5 5 0 PKD domain DUF3185 PF11381.3 CBK21633.2 - 6.2 6.6 10.4 17 5.2 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) DUF1336 PF07059.7 CBK21634.2 - 6.7e-13 48.5 0.0 7.9e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) RhoGAP PF00620.22 CBK21635.2 - 4e-13 49.2 0.0 6.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 CBK21635.2 - 8.4e-11 42.2 0.1 1.7e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_12 PF13087.1 CBK21636.2 - 1.8e-26 92.7 0.0 2.2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CBK21636.2 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PRP38 PF03371.10 CBK21636.2 - 0.065 12.8 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 PRP38 family Viral_helicase1 PF01443.13 CBK21636.2 - 0.12 11.8 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.20 CBK21637.2 - 2.3e-66 223.6 0.0 2.8e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21637.2 - 1.3e-31 109.5 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21637.2 - 0.00012 21.1 0.0 0.00042 19.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBK21637.2 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK21637.2 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arb2 PF09757.4 CBK21638.2 - 4.6e-13 48.9 0.0 8.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Arb2 domain B56 PF01603.15 CBK21639.2 - 4.5e-93 312.0 1.2 4.9e-93 311.9 0.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dopey_N PF04118.9 CBK21639.2 - 0.052 12.3 0.3 3.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Dopey, N-terminal HSP70 PF00012.15 CBK21640.2 - 9.5e-08 30.4 0.0 9.5e-08 30.4 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein NT-C2 PF10358.4 CBK21640.2 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_S3_C PF00189.15 CBK21641.2 - 1.2e-15 57.4 0.2 2e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBK21641.2 - 2.3e-11 43.1 0.2 4.1e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CBK21641.2 - 0.0099 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 SHMT PF00464.14 CBK21642.2 - 5.7e-178 591.3 0.0 6.5e-178 591.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBK21642.2 - 0.0045 16.1 0.1 0.02 14.0 0.0 1.8 1 1 1 2 2 2 1 Beta-eliminating lyase Macro PF01661.16 CBK21642.2 - 0.031 14.1 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Macro domain LSM PF01423.17 CBK21643.2 - 4.8e-09 35.6 0.0 5.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain PCIF1_WW PF12237.3 CBK21644.2 - 1.2e-41 141.9 1.3 2.1e-41 141.1 0.9 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain CPSF100_C PF13299.1 CBK21645.2 - 3e-06 27.5 0.0 0.0093 16.1 0.0 2.5 2 0 0 2 2 2 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 CBK21645.2 - 0.00074 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase DUF2204 PF09970.4 CBK21645.2 - 0.0022 17.4 0.5 0.0058 16.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase of unknown function (DUF2204) Peroxin-22 PF12827.2 CBK21645.2 - 0.015 14.9 1.7 0.088 12.5 0.5 2.1 1 1 1 2 2 2 0 Peroxisomal biogenesis protein family Beta-Casp PF10996.3 CBK21646.2 - 2.9e-14 53.0 0.0 5.8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CBK21646.2 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBK21646.2 - 0.0034 16.9 0.1 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PI3_PI4_kinase PF00454.22 CBK21649.2 - 4.4e-34 117.9 0.2 9.1e-34 116.9 0.1 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBK21649.2 - 6e-15 54.3 0.0 1.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 FATC domain WW PF00397.21 CBK21650.2 - 4.4e-08 32.8 13.9 0.0001 22.0 0.1 2.8 3 0 0 3 3 3 2 WW domain Colicin_Pyocin PF01320.13 CBK21650.2 - 0.0026 17.5 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Colicin immunity protein / pyocin immunity protein RhoGEF PF00621.15 CBK21650.2 - 0.061 13.1 1.6 0.087 12.6 0.0 2.0 2 1 0 2 2 2 0 RhoGEF domain Sugar_transport PF06800.7 CBK21651.2 - 2.4e-07 30.1 0.3 2.8e-07 29.8 0.2 1.0 1 0 0 1 1 1 1 Sugar transport protein EmrE PF13536.1 CBK21651.2 - 0.01 16.0 1.8 0.012 15.8 1.2 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Tmemb_14 PF03647.8 CBK21651.2 - 0.82 10.1 7.4 1.4 9.3 5.2 1.4 1 1 0 1 1 1 0 Transmembrane proteins 14C Ureide_permease PF07168.6 CBK21652.2 - 0.0046 15.6 0.0 0.0076 14.9 0.0 1.3 1 0 0 1 1 1 1 Ureide permease Shisa PF13908.1 CBK21652.2 - 0.015 15.4 2.6 0.022 14.9 1.2 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FAP PF07174.6 CBK21652.2 - 0.39 9.9 11.6 0.6 9.3 8.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Lamp PF01299.12 CBK21652.2 - 0.96 8.5 5.9 1.4 7.9 4.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) adh_short PF00106.20 CBK21653.2 - 3.9e-07 30.1 0.0 7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase tRNA-synt_2 PF00152.15 CBK21654.2 - 2.9e-75 253.1 0.3 8.3e-75 251.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 CBK21654.2 - 4.4e-15 55.0 2.4 1.5e-14 53.3 1.7 2.0 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.20 CBK21654.2 - 1.2e-07 31.4 0.4 2.1e-07 30.6 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBK21654.2 - 8.4e-05 21.8 0.1 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF383 PF04063.9 CBK21655.2 - 3.4e-22 78.9 2.0 1.2e-20 73.8 0.1 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF383) DUF384 PF04064.8 CBK21655.2 - 2.5e-09 36.5 0.5 8.3e-09 34.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 CBK21655.2 - 0.00025 21.2 0.2 0.018 15.3 0.3 2.9 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 CBK21655.2 - 0.011 15.7 0.7 0.057 13.5 0.0 2.6 3 0 0 3 3 3 0 HEAT repeat Proteasom_PSMB PF10508.4 CBK21655.2 - 0.019 13.2 3.7 0.052 11.8 0.9 2.3 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 CBK21655.2 - 0.053 14.0 0.2 16 6.1 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat 4HBT_2 PF13279.1 CBK21656.2 - 1.1e-11 45.1 0.0 1.4e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CBK21656.2 - 2.5e-07 30.7 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CBK21656.2 - 0.12 11.3 0.6 0.7 8.7 0.1 1.9 2 0 0 2 2 2 0 Acyl-ACP thioesterase YIF1 PF03878.10 CBK21657.2 - 1e-41 142.6 4.5 1.4e-41 142.2 3.1 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CBK21657.2 - 0.0017 17.8 5.6 0.0026 17.2 3.9 1.3 1 0 0 1 1 1 1 Yip1 domain CorA PF01544.13 CBK21658.2 - 6.2e-38 130.4 0.3 8.4e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ETRAMP PF09716.5 CBK21658.2 - 0.076 12.9 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) EF-hand_8 PF13833.1 CBK21659.2 - 1.1e-12 47.3 1.1 2.6e-06 26.9 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBK21659.2 - 3.4e-11 41.5 0.6 5.7e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBK21659.2 - 1.7e-10 39.8 0.4 1.7e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBK21659.2 - 2.2e-10 39.3 0.4 1.5e-06 27.2 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBK21659.2 - 3.4e-09 36.7 1.3 6.4e-09 35.8 0.9 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 CBK21659.2 - 0.015 14.9 0.2 0.029 14.0 0.0 1.5 1 1 1 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 CBK21659.2 - 0.022 14.8 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3215 PF11503.3 CBK21659.2 - 0.079 12.5 0.1 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Mito_carr PF00153.22 CBK21660.2 - 6.3e-58 192.4 7.6 1.1e-24 85.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1470 PF07336.6 CBK21661.2 - 0.5 10.6 3.5 0.67 10.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) DUF4229 PF14012.1 CBK21662.2 - 9.1 6.2 9.8 13 5.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) RRM_1 PF00076.17 CBK21663.2 - 2.9e-25 87.6 0.0 7.1e-16 57.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21663.2 - 2.6e-16 59.3 0.0 2.9e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK21663.2 - 5.7e-10 38.8 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK21663.2 - 0.0029 17.4 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif IBB PF01749.15 CBK21664.2 - 1.2 9.3 7.9 2.2 8.4 5.5 1.4 1 0 0 1 1 1 0 Importin beta binding domain Pkinase PF00069.20 CBK21665.2 - 6.6e-31 107.3 0.0 7.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21665.2 - 4.5e-16 58.7 0.0 5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21665.2 - 0.00027 19.9 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK21665.2 - 0.01 14.8 0.0 0.021 13.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Curto_V3 PF07436.6 CBK21665.2 - 0.033 14.3 0.0 0.66 10.1 0.0 2.2 1 1 1 2 2 2 0 Curtovirus V3 protein Pox_ser-thr_kin PF05445.6 CBK21665.2 - 0.055 12.2 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CBK21665.2 - 0.092 12.4 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Calreticulin PF00262.13 CBK21666.2 - 2.9e-114 381.5 17.5 4.3e-114 380.9 12.1 1.2 1 0 0 1 1 1 1 Calreticulin family Ank_4 PF13637.1 CBK21667.2 - 1.4e-13 50.9 0.0 1e-08 35.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBK21667.2 - 3.8e-12 46.3 0.0 1.7e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21667.2 - 2.7e-10 39.5 0.1 0.0012 18.5 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBK21667.2 - 2.4e-09 37.1 0.0 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK21667.2 - 2.6e-07 30.2 0.2 0.012 15.8 0.0 4.2 3 2 0 3 3 3 2 Ankyrin repeat Glyco_trans_1_2 PF13524.1 CBK21667.2 - 0.069 13.4 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sdh_cyt PF01127.17 CBK21668.2 - 8.5e-14 51.4 3.8 1.2e-13 50.9 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1691 PF07950.6 CBK21668.2 - 0.14 12.1 1.1 7.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Ribosomal_L40e PF01020.12 CBK21669.2 - 1e-31 108.2 13.7 1.7e-31 107.5 9.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBK21669.2 - 1.7e-17 62.5 0.0 2.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK21669.2 - 6.2e-11 41.8 0.3 8.9e-11 41.3 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK21669.2 - 0.025 14.7 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PCP_red PF08369.5 CBK21670.2 - 2.5 8.0 7.1 13 5.7 0.2 2.8 2 1 1 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit TM2 PF05154.11 CBK21671.2 - 3.3 7.9 11.7 0.21 11.8 2.3 2.0 2 0 0 2 2 2 0 TM2 domain Pep_deformylase PF01327.16 CBK21672.2 - 1.9e-30 105.3 0.0 3.3e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Polypeptide deformylase zf-CHCC PF10276.4 CBK21673.2 - 5.5e-10 38.9 2.9 8e-10 38.3 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-FCS PF06467.9 CBK21673.2 - 0.011 15.3 0.3 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.1 CBK21673.2 - 0.076 12.5 1.2 0.18 11.3 0.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 CBK21673.2 - 1.1 9.0 4.0 0.4 10.4 0.6 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 CBK21673.2 - 2.3 8.7 4.0 2.1 8.8 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_C1 PF00112.18 CBK21674.2 - 8.8e-101 336.3 26.3 5e-57 193.2 4.3 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBK21674.2 - 0.0087 14.6 12.2 0.03 12.8 1.1 3.1 3 0 0 3 3 3 2 Peptidase C1-like family Ketoacyl-synt_C PF02801.17 CBK21675.2 - 2.6e-27 95.0 0.1 4.9e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 CBK21675.2 - 1.5e-17 63.9 1.1 3e-17 62.9 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 CBK21675.2 - 0.0031 16.5 0.0 0.014 14.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBK21675.2 - 0.04 13.3 0.3 0.078 12.4 0.2 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain Alg14 PF08660.6 CBK21676.2 - 9.9e-53 178.6 0.0 1.2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Proteasom_Rpn13 PF04683.8 CBK21677.2 - 0.00036 20.5 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Linker_histone PF00538.14 CBK21678.2 - 1.9e-10 40.6 1.7 3.1e-10 39.9 0.0 2.2 1 1 1 2 2 2 1 linker histone H1 and H5 family Mitofilin PF09731.4 CBK21678.2 - 0.043 12.4 48.8 0.052 12.2 33.8 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 CBK21678.2 - 7.7 4.0 36.6 9.6 3.7 25.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sugar_transport PF06800.7 CBK21680.2 - 5.1e-09 35.6 1.1 2.1e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Sugar transport protein EmrE PF13536.1 CBK21680.2 - 5 7.3 20.6 0.041 14.0 4.6 3.3 2 2 1 3 3 3 0 Multidrug resistance efflux transporter Ank_2 PF12796.2 CBK21681.2 - 5.1e-24 84.4 0.0 5.6e-06 26.6 0.0 5.8 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBK21681.2 - 6.2e-23 79.4 17.4 0.00064 19.4 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 CBK21681.2 - 5.9e-18 64.8 7.5 0.00052 20.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBK21681.2 - 3.7e-17 61.9 15.8 0.085 13.1 0.1 7.9 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK21681.2 - 2.3e-13 48.9 4.6 0.36 11.1 0.0 8.7 8 0 0 8 8 8 3 Ankyrin repeat FYVE PF01363.16 CBK21681.2 - 1.6e-09 37.5 13.6 5.3e-09 35.8 9.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CBK21681.2 - 0.00013 21.8 9.0 0.00028 20.7 6.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Mito_carr PF00153.22 CBK21682.2 - 2.9e-11 42.9 0.1 3e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein LRR_8 PF13855.1 CBK21683.2 - 0.00036 20.2 2.7 0.58 9.9 0.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK21683.2 - 0.00084 18.9 0.5 2.6 7.7 0.0 3.1 2 2 0 2 2 2 2 Leucine Rich repeats (2 copies) FTH PF01827.22 CBK21683.2 - 0.029 13.9 0.8 7 6.2 0.1 2.9 2 1 1 3 3 3 0 FTH domain LRR_1 PF00560.28 CBK21683.2 - 0.098 12.7 0.7 49 4.5 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 CBK21683.2 - 0.37 10.9 4.4 58 4.2 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeat RNase_PH PF01138.16 CBK21684.2 - 7.7e-14 52.1 0.3 2e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBK21684.2 - 3.9e-06 26.7 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1253 PF06862.7 CBK21685.2 - 2.7e-86 289.7 0.0 3.9e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) CLASP_N PF12348.3 CBK21686.2 - 1.1e-06 28.1 1.7 1.8e-06 27.4 1.2 1.3 1 0 0 1 1 1 1 CLASP N terminal CAP_GLY PF01302.20 CBK21686.2 - 0.016 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain zf-DHHC PF01529.15 CBK21687.2 - 2.1e-25 89.1 11.4 2.3e-25 89.0 7.9 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase PSI PF01437.20 CBK21687.2 - 0.25 11.5 4.9 0.45 10.7 3.4 1.4 1 0 0 1 1 1 0 Plexin repeat DUF2726 PF10881.3 CBK21689.2 - 0.089 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) WD40 PF00400.27 CBK21690.2 - 8e-54 177.7 13.3 1.9e-10 40.1 0.0 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CBK21690.2 - 0.0015 18.2 0.0 0.65 9.6 0.1 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CBK21690.2 - 0.013 14.6 0.1 1.2 8.2 0.0 3.3 2 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CBK21690.2 - 0.016 13.5 0.0 3.5 5.8 0.0 2.9 1 1 2 3 3 3 0 Cytochrome D1 heme domain DUF3312 PF11768.3 CBK21690.2 - 0.083 11.1 0.0 0.28 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) APG6 PF04111.7 CBK21691.2 - 3.2e-09 36.2 0.0 3.8e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF1281 PF06924.6 CBK21691.2 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) MFS_1 PF07690.11 CBK21693.2 - 4e-31 107.9 0.8 4.2e-31 107.9 0.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK21693.2 - 1.7e-19 69.7 3.5 2.1e-19 69.4 2.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.13 CBK21693.2 - 0.0001 21.0 0.4 0.00013 20.6 0.3 1.0 1 0 0 1 1 1 1 Reduced folate carrier DUF106 PF01956.11 CBK21693.2 - 0.001 18.6 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 Integral membrane protein DUF106 TRI12 PF06609.8 CBK21693.2 - 0.0016 16.7 1.1 0.0019 16.4 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CBK21693.2 - 0.0022 16.4 5.3 0.013 13.9 1.6 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 CBK21693.2 - 0.015 13.7 7.6 0.013 13.9 4.0 1.8 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF2232 PF09991.4 CBK21693.2 - 0.017 14.1 0.0 0.017 14.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Mem_trans PF03547.13 CBK21693.2 - 0.049 11.9 0.1 0.065 11.5 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein LacY_symp PF01306.14 CBK21693.2 - 0.053 12.0 5.4 0.061 11.8 3.3 1.3 1 1 0 1 1 1 0 LacY proton/sugar symporter Galanin PF01296.13 CBK21693.2 - 0.087 12.6 0.4 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Galanin Peptidase_A24 PF01478.13 CBK21693.2 - 0.8 9.8 6.9 2.1 8.5 4.8 1.7 1 1 0 1 1 1 0 Type IV leader peptidase family He_PIG PF05345.7 CBK21694.2 - 0.0011 18.9 3.1 0.0049 16.8 2.2 2.2 1 1 0 1 1 1 1 Putative Ig domain TMEM154 PF15102.1 CBK21694.2 - 0.0043 16.7 0.1 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Sushi PF00084.15 CBK21694.2 - 0.048 14.0 8.6 0.046 14.0 1.0 3.0 3 0 0 3 3 3 0 Sushi domain (SCR repeat) Rifin_STEVOR PF02009.11 CBK21694.2 - 0.059 13.0 1.4 0.1 12.2 0.9 1.3 1 0 0 1 1 1 0 Rifin/stevor family ASFV_J13L PF05568.6 CBK21694.2 - 0.063 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein P12 PF12669.2 CBK21694.2 - 0.078 13.1 1.8 0.18 12.0 1.2 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family He_PIG PF05345.7 CBK21695.2 - 1.1e-21 76.5 61.9 3.8e-07 30.0 1.5 8.9 8 1 0 8 8 8 5 Putative Ig domain PA14 PF07691.7 CBK21695.2 - 1.8e-21 76.3 0.7 3.6e-12 46.1 0.1 3.9 3 0 0 3 3 3 2 PA14 domain F5_F8_type_C PF00754.20 CBK21695.2 - 0.0022 17.8 2.8 0.0084 15.9 1.9 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF3413 PF11893.3 CBK21695.2 - 0.038 12.8 0.3 0.064 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) HRM PF02793.17 CBK21695.2 - 0.044 13.7 0.6 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Hormone receptor domain DUF912 PF06024.7 CBK21695.2 - 0.1 12.6 0.5 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2500 PF10694.4 CBK21695.2 - 0.12 12.3 0.7 0.33 10.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF2363 PF10155.4 CBK21696.2 - 6.5e-08 32.5 1.8 6.5e-08 32.5 1.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2363) Abhydrolase_3 PF07859.8 CBK21697.2 - 5.9e-36 124.0 0.0 7.2e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBK21697.2 - 1.3e-05 24.5 0.0 1.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBK21697.2 - 2.9e-05 23.7 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CBK21697.2 - 8.8e-05 21.3 0.0 0.00011 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBK21697.2 - 0.00042 20.0 0.0 0.00048 19.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CBK21697.2 - 0.0018 17.0 0.0 0.003 16.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 CBK21697.2 - 0.019 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family APG6 PF04111.7 CBK21698.2 - 0.00082 18.5 5.6 0.00082 18.5 3.9 2.3 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF4200 PF13863.1 CBK21698.2 - 0.004 17.1 2.6 0.004 17.1 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) DUF3074 PF11274.3 CBK21698.2 - 0.015 14.9 0.2 0.086 12.4 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) TBPIP PF07106.8 CBK21698.2 - 0.025 14.1 0.7 0.025 14.1 0.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_2 PF07716.10 CBK21698.2 - 0.062 13.1 10.4 0.22 11.3 0.2 3.1 2 1 1 3 3 3 0 Basic region leucine zipper Ndufs5 PF10200.4 CBK21698.2 - 0.082 12.9 0.1 0.28 11.2 0.1 2.0 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Reo_sigmaC PF04582.7 CBK21698.2 - 0.12 11.4 8.4 0.029 13.5 1.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein M PF02370.11 CBK21698.2 - 0.15 12.5 2.9 1.6 9.3 0.3 3.3 2 0 0 2 2 2 0 M protein repeat GAS PF13851.1 CBK21698.2 - 0.22 10.6 9.5 0.016 14.4 1.7 2.5 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 CBK21698.2 - 0.69 10.0 6.0 0.33 11.0 1.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 CBK21698.2 - 1.4 8.7 15.3 0.063 13.1 4.7 2.7 2 2 1 2 2 2 0 Tropomyosin like DUF2968 PF11180.3 CBK21698.2 - 1.5 8.2 10.7 1.6 8.0 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 CBK21698.2 - 1.8 8.0 6.6 3.3 7.2 0.2 3.0 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBK21698.2 - 7.6 6.4 13.7 0.31 10.8 1.7 3.8 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBK21698.2 - 7.8 6.5 10.5 0.33 10.9 1.7 2.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Formyl_trans_N PF00551.14 CBK21699.2 - 9e-17 61.1 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CBK21699.2 - 1.5e-10 41.0 0.0 4.2e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain RIO1 PF01163.17 CBK21700.2 - 1.1e-73 246.6 1.5 1.7e-73 245.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBK21700.2 - 0.00064 19.5 0.2 0.76 9.4 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1840 PF08895.6 CBK21700.2 - 1.7 8.7 11.9 24 5.0 2.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Ribosomal_L3 PF00297.17 CBK21701.2 - 1.8e-114 381.5 8.0 2.2e-114 381.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR PF01535.15 CBK21702.2 - 0.00064 19.5 0.2 0.022 14.7 0.0 3.3 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 CBK21702.2 - 0.007 16.3 0.1 0.18 11.8 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family TPR_2 PF07719.12 CBK21702.2 - 0.011 15.5 1.0 0.052 13.4 0.7 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21702.2 - 0.012 15.2 1.4 0.039 13.5 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBK21702.2 - 0.017 15.4 0.6 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1186 PF06685.6 CBK21702.2 - 0.025 13.7 0.7 0.046 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) SE PF08491.5 CBK21702.2 - 0.026 13.3 0.4 1.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Squalene epoxidase PPR_3 PF13812.1 CBK21702.2 - 0.031 14.5 0.0 1.5 9.3 0.0 3.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_12 PF13424.1 CBK21702.2 - 0.083 12.8 0.2 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK21702.2 - 0.096 13.3 0.0 1.3 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGEF PF00621.15 CBK21703.2 - 1e-51 175.3 0.2 1.3e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain Peptidase_S31 PF05578.7 CBK21703.2 - 0.042 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 Bromodomain PF00439.20 CBK21704.2 - 2.3e-19 69.1 0.0 1.3e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Bromodomain GreA_GreB_N PF03449.10 CBK21704.2 - 0.0036 17.3 3.6 0.35 10.9 0.8 3.0 3 0 0 3 3 3 1 Transcription elongation factor, N-terminal CALCOCO1 PF07888.6 CBK21704.2 - 0.036 12.3 9.9 0.048 11.9 6.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Pox_A_type_inc PF04508.7 CBK21704.2 - 0.11 12.3 0.4 0.62 9.9 0.3 2.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Macoilin PF09726.4 CBK21704.2 - 0.12 10.6 5.3 0.17 10.1 3.7 1.3 1 0 0 1 1 1 0 Transmembrane protein LZ_Tnp_IS66 PF13007.2 CBK21704.2 - 0.59 10.8 0.1 0.59 10.8 0.1 3.1 2 1 1 3 3 3 0 Transposase C of IS166 homeodomain LRS4 PF10422.4 CBK21704.2 - 0.82 8.9 7.7 0.22 10.8 3.1 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Mnd1 PF03962.10 CBK21704.2 - 0.86 9.2 9.7 1.8 8.2 6.8 1.6 1 1 0 1 1 1 0 Mnd1 family TBPIP PF07106.8 CBK21704.2 - 1.1 8.8 7.7 1.2 8.7 3.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1192 PF06698.6 CBK21704.2 - 1.4 8.7 5.4 0.36 10.6 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) KAT11 PF08214.6 CBK21705.2 - 6e-21 74.9 0.6 2.5e-20 72.8 0.1 1.8 1 1 1 2 2 2 1 Histone acetylation protein PHD PF00628.24 CBK21705.2 - 0.00021 20.9 1.8 0.00021 20.9 1.2 2.2 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 CBK21705.2 - 3.6 7.4 11.3 0.078 12.8 2.5 2.2 2 0 0 2 2 2 0 Ring finger domain zf-TAZ PF02135.11 CBK21706.2 - 1.4e-07 31.4 15.2 1.6e-07 31.2 10.6 1.0 1 0 0 1 1 1 1 TAZ zinc finger VWC PF00093.13 CBK21706.2 - 0.45 10.6 14.9 2 8.6 1.0 2.1 1 1 1 2 2 2 0 von Willebrand factor type C domain Adaptin_N PF01602.15 CBK21707.2 - 5e-73 246.2 1.1 6.2e-73 245.8 0.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBK21707.2 - 2.5e-40 137.7 0.0 4.5e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBK21707.2 - 1.9e-06 28.0 18.3 0.0003 20.9 0.3 4.7 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 CBK21707.2 - 0.0057 16.6 16.2 1.1 9.4 0.7 5.8 5 0 0 5 5 5 2 HEAT repeat DUF2013 PF09431.5 CBK21707.2 - 0.095 12.4 0.3 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) HEAT_PBS PF03130.11 CBK21707.2 - 0.49 11.0 5.4 3.2 8.4 1.4 3.9 2 1 1 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CBK21707.2 - 0.57 10.7 28.4 0.25 11.9 3.6 6.2 5 1 0 5 5 5 0 HEAT-like repeat Arm PF00514.18 CBK21707.2 - 0.83 9.5 4.2 3.1 7.7 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Peptidase_C1 PF00112.18 CBK21708.2 - 1.4e-69 234.3 4.6 1.8e-69 233.9 3.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK21708.2 - 1.3e-17 63.7 0.2 2.1e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBK21708.2 - 2.2e-07 29.7 0.6 4.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ESAG1 PF03238.8 CBK21708.2 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 ESAG protein PIF1 PF05970.9 CBK21709.2 - 5.8e-35 120.9 0.1 2.4e-21 76.1 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CBK21709.2 - 2.2e-06 27.4 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Glyoxalase_4 PF13669.1 CBK21710.2 - 1.2e-18 67.1 0.0 1.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CBK21710.2 - 0.0014 19.2 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CBK21710.2 - 0.12 12.3 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-DHHC PF01529.15 CBK21711.2 - 3.8e-27 94.7 17.9 3.8e-27 94.7 12.4 2.1 2 1 1 3 3 3 1 DHHC palmitoyltransferase Claudin_2 PF13903.1 CBK21711.2 - 0.0027 17.4 1.6 0.0051 16.5 1.1 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Pex24p PF06398.6 CBK21711.2 - 0.63 8.7 9.9 0.013 14.3 0.9 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin ABC_tran PF00005.22 CBK21712.2 - 2.1e-47 160.8 0.7 6e-22 78.4 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CBK21712.2 - 6.4e-19 69.0 7.8 4.5e-07 30.1 0.2 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CBK21712.2 - 3e-11 42.9 0.5 0.0069 15.6 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBK21712.2 - 1.1e-06 28.1 0.0 0.048 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK21712.2 - 2.7e-06 28.1 3.5 0.048 14.4 0.1 4.0 4 0 0 4 4 4 2 AAA domain ABC_tran_2 PF12848.2 CBK21712.2 - 3e-06 26.9 6.7 3e-06 26.9 4.7 3.9 3 1 0 4 4 2 1 ABC transporter AAA_10 PF12846.2 CBK21712.2 - 7e-06 25.6 0.2 0.032 13.6 0.0 3.0 2 1 1 3 3 3 2 AAA-like domain DUF258 PF03193.11 CBK21712.2 - 1.6e-05 24.1 0.0 0.021 14.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 CBK21712.2 - 3.8e-05 23.8 0.0 0.86 9.7 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBK21712.2 - 6.7e-05 22.6 0.2 0.23 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 CBK21712.2 - 8.8e-05 22.4 0.6 0.23 11.3 0.2 3.7 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CBK21712.2 - 0.00072 19.0 0.0 0.7 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CBK21712.2 - 0.00082 19.5 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 CBK21712.2 - 0.0013 18.4 0.8 0.88 9.2 0.1 3.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBK21712.2 - 0.0015 18.5 1.5 0.48 10.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CBK21712.2 - 0.0019 18.0 0.0 4.7 7.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 CBK21712.2 - 0.0031 17.9 9.4 0.39 11.2 0.0 4.1 4 0 0 4 4 4 2 Miro-like protein SbcCD_C PF13558.1 CBK21712.2 - 0.0053 16.6 0.4 3.1 7.7 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CBK21712.2 - 0.0064 16.6 7.7 0.21 11.7 0.0 3.7 4 1 0 4 4 3 2 AAA domain NTPase_1 PF03266.10 CBK21712.2 - 0.0073 16.0 0.4 2.4 7.8 0.0 3.1 2 1 1 3 3 3 1 NTPase MMR_HSR1 PF01926.18 CBK21712.2 - 0.018 15.0 0.0 11 6.0 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_5 PF07728.9 CBK21712.2 - 0.042 13.5 0.1 8 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK21712.2 - 0.22 11.8 0.1 0.22 11.8 0.1 5.1 3 2 0 4 4 2 0 AAA domain DUF262 PF03235.9 CBK21712.2 - 7.8 6.4 17.7 1.5 8.7 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF262 Aa_trans PF01490.13 CBK21714.2 - 1.2e-48 165.6 33.9 1.5e-48 165.3 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2231 PF09990.4 CBK21714.2 - 0.045 14.1 0.3 0.045 14.1 0.2 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2231) DUF202 PF02656.10 CBK21714.2 - 0.11 12.7 6.6 4 7.7 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) UPF0020 PF01170.13 CBK21715.2 - 7.7e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBK21715.2 - 6.7e-08 32.5 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CBK21715.2 - 0.00013 21.5 0.0 0.0017 17.9 0.0 2.4 2 1 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.10 CBK21715.2 - 0.0038 16.6 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 EGF_2 PF07974.8 CBK21716.2 - 0.0078 16.3 8.5 0.0078 16.3 5.9 7.0 5 2 0 5 5 5 3 EGF-like domain Brix PF04427.13 CBK21717.2 - 2.1e-47 161.2 1.2 3.1e-47 160.7 0.8 1.2 1 0 0 1 1 1 1 Brix domain LIM PF00412.17 CBK21718.2 - 0.45 10.6 2.4 0.96 9.5 0.4 2.2 2 0 0 2 2 2 0 LIM domain DUF581 PF04570.9 CBK21718.2 - 0.58 9.4 3.2 0.77 9.0 0.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF581) LRR_5 PF13306.1 CBK21719.2 - 0.39 10.4 7.4 0.35 10.5 1.0 2.7 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) UQ_con PF00179.21 CBK21720.2 - 2e-38 130.9 0.0 2.6e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK21720.2 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK21720.2 - 0.027 14.3 0.2 0.038 13.8 0.1 1.7 1 1 0 1 1 1 0 RWD domain UCH PF00443.24 CBK21721.2 - 7.3e-12 44.9 0.0 8.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21721.2 - 0.059 12.7 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 CBK21722.2 - 2.5e-23 82.5 0.0 4.1e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21722.2 - 0.00038 19.9 0.0 0.0009 18.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RCC1 PF00415.13 CBK21723.2 - 4.4e-43 145.2 8.3 1.9e-12 47.1 0.0 5.5 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK21723.2 - 6.9e-21 73.3 27.7 6.1e-08 32.0 0.2 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Nucleoporin_N PF08801.6 CBK21723.2 - 0.0074 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like RRM_1 PF00076.17 CBK21724.2 - 2.3e-06 27.1 0.1 3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21724.2 - 0.0068 16.3 0.0 0.0092 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SDH_alpha PF03313.10 CBK21726.2 - 5.6e-81 271.6 8.1 7.9e-81 271.1 5.6 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CBK21726.2 - 1.5e-30 106.3 0.3 2.9e-20 72.9 0.0 2.4 1 1 1 2 2 2 2 Serine dehydratase beta chain CBM_X2 PF03442.9 CBK21726.2 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 TCR PF03638.10 CBK21727.2 - 2.5e-25 88.0 53.9 1.2e-12 47.4 15.7 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain K_channel_TID PF07941.6 CBK21727.2 - 0.96 9.7 7.1 3.7 7.8 3.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MRG PF05712.8 CBK21729.2 - 3.1e-17 62.0 0.7 3.7e-17 61.8 0.5 1.0 1 0 0 1 1 1 1 MRG AA_permease PF00324.16 CBK21730.2 - 2.9e-13 48.9 10.8 3e-13 48.9 7.5 1.0 1 0 0 1 1 1 1 Amino acid permease FeoB_C PF07664.7 CBK21730.2 - 0.36 10.2 2.6 0.75 9.2 0.2 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus AA_permease PF00324.16 CBK21731.2 - 2.2e-43 148.3 14.6 2.8e-43 147.9 10.1 1.1 1 0 0 1 1 1 1 Amino acid permease Collagen PF01391.13 CBK21732.2 - 1.6e-31 107.5 106.7 5e-10 38.7 18.7 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Actin PF00022.14 CBK21733.2 - 8.7e-101 337.1 0.0 1.1e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBK21733.2 - 0.16 12.3 0.1 0.53 10.7 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DAP3 PF10236.4 CBK21734.2 - 1.6e-29 102.8 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CBK21734.2 - 5e-05 23.3 0.0 0.00019 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBK21734.2 - 0.0073 16.4 0.0 0.034 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK21734.2 - 0.023 14.6 0.0 0.081 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK21734.2 - 0.038 13.6 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 CBK21734.2 - 0.045 13.4 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK21734.2 - 0.068 13.4 0.1 0.29 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain NDUF_B12 PF08122.7 CBK21735.2 - 2.2e-05 24.0 0.4 2.6e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Nop25 PF09805.4 CBK21736.2 - 1.2e-06 28.6 31.8 8e-05 22.7 22.0 2.5 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) RHH_1 PF01402.16 CBK21736.2 - 2 8.4 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Metallophos PF00149.23 CBK21738.2 - 1e-42 145.7 0.2 1.4e-42 145.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4095 PF13338.1 CBK21738.2 - 0.033 14.3 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) GBP PF02263.14 CBK21739.2 - 7.6e-44 149.7 0.1 5.7e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain Ribosomal_S14 PF00253.16 CBK21740.2 - 1.5e-17 62.6 4.0 1.7e-17 62.5 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e FYVE PF01363.16 CBK21740.2 - 0.089 12.6 0.6 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 CBK21740.2 - 0.11 12.3 0.8 0.16 11.8 0.6 1.3 1 1 0 1 1 1 0 Double zinc ribbon zf-dskA_traR PF01258.12 CBK21740.2 - 0.14 11.9 2.8 2.6 7.8 0.2 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ATP-grasp_5 PF13549.1 CBK21741.2 - 1.1e-54 184.9 0.0 1.6e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CBK21741.2 - 2e-40 137.5 0.0 2.5e-39 134.0 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK21741.2 - 4.5e-19 68.7 0.0 1.3e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Abhydrolase_6 PF12697.2 CBK21742.2 - 3.9e-24 85.8 0.0 5e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBK21742.2 - 2.6e-10 40.2 0.0 3.8e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBK21742.2 - 5.6e-07 30.0 0.0 1.4e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 CBK21742.2 - 8e-06 25.5 0.0 0.00082 18.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 CBK21742.2 - 7.1e-05 21.7 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.8 CBK21742.2 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 CBK21742.2 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2305 PF10230.4 CBK21742.2 - 0.005 16.3 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2974 PF11187.3 CBK21742.2 - 0.0052 16.1 0.1 0.02 14.2 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 CBK21742.2 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 CBK21742.2 - 0.1 12.1 0.1 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PG_binding_1 PF01471.13 CBK21742.2 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain PCI PF01399.22 CBK21743.2 - 4.9e-06 26.7 0.6 8.9e-06 25.9 0.0 1.9 2 1 0 2 2 2 1 PCI domain Suf PF05843.9 CBK21743.2 - 0.44 10.2 15.4 0.58 9.8 10.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gag_spuma PF03276.9 CBK21743.2 - 0.61 8.3 17.3 0.68 8.1 12.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4557 PF15101.1 CBK21743.2 - 1.1 9.0 13.1 1.4 8.7 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) eIF-3c_N PF05470.7 CBK21744.2 - 1.2e-15 56.6 0.0 1.3e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus eIF-3c_N PF05470.7 CBK21745.2 - 5.7e-30 103.9 10.9 7e-30 103.6 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus tRNA-synt_1e PF01406.14 CBK21745.2 - 0.0051 15.9 0.9 0.0067 15.5 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MbeB_N PF04837.7 CBK21745.2 - 0.039 14.0 0.2 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF1786 PF08735.5 CBK21745.2 - 0.074 12.2 0.2 0.091 11.9 0.2 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) IlvC PF01450.14 CBK21745.2 - 0.56 10.1 2.9 4.6 7.1 0.1 2.1 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Spermine_synth PF01564.12 CBK21746.2 - 5.1e-85 284.3 0.0 7e-85 283.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 CBK21746.2 - 4e-05 24.1 0.0 7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 CBK21746.2 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.1 CBK21746.2 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK21746.2 - 0.008 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK21746.2 - 0.094 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CBK21746.2 - 0.096 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldose_epim PF01263.15 CBK21748.2 - 1.3e-41 142.6 0.1 1.6e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PUA_2 PF14306.1 CBK21748.2 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PUA-like domain HRM PF02793.17 CBK21749.2 - 3.5e-16 58.9 32.6 8.6e-10 38.4 3.0 5.4 2 1 3 5 5 5 4 Hormone receptor domain Sushi PF00084.15 CBK21749.2 - 1.1e-07 32.0 30.7 0.00057 20.1 1.9 5.7 5 1 1 6 6 6 4 Sushi domain (SCR repeat) DUF4493 PF14900.1 CBK21749.2 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) Pkinase PF00069.20 CBK21750.2 - 4.2e-34 117.8 0.0 4.9e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21750.2 - 2.1e-09 36.8 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK21750.2 - 0.031 13.9 0.0 0.93 9.1 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family DNA_pol_B_2 PF03175.8 CBK21751.2 - 0.00019 20.2 0.2 0.00037 19.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TF_Zn_Ribbon PF08271.7 CBK21751.2 - 0.88 8.9 5.2 2.7 7.3 0.1 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding CybS PF05328.7 CBK21753.2 - 8.6e-13 48.0 0.8 1.1e-12 47.6 0.6 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 CBK21753.2 - 0.035 13.9 0.2 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Thioredoxin_7 PF13899.1 CBK21754.2 - 3.5e-10 39.7 0.0 4.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.10 CBK21754.2 - 0.0014 18.3 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Gin PF10764.4 CBK21754.2 - 0.0017 18.0 3.4 0.0023 17.5 0.9 2.2 2 0 0 2 2 2 1 Inhibitor of sigma-G Gin AhpC-TSA PF00578.16 CBK21754.2 - 0.0095 15.6 0.4 1.1 8.9 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family Neisseria_PilC PF05567.6 CBK21754.2 - 0.015 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Thioredoxin_2 PF13098.1 CBK21754.2 - 0.025 14.7 0.1 0.039 14.1 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.5 CBK21754.2 - 0.074 12.5 0.1 4.8 6.7 0.0 2.1 1 1 1 2 2 2 0 Redoxin zf-met2 PF12907.2 CBK21755.2 - 1.4e-15 56.9 1.3 1.4e-15 56.9 0.9 2.0 2 0 0 2 2 2 1 Zinc-binding zf-Di19 PF05605.7 CBK21755.2 - 0.3 11.2 1.6 2.4 8.3 0.9 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L18p PF00861.17 CBK21756.2 - 2.6e-42 143.7 0.5 2.6e-42 143.7 0.3 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBK21756.2 - 1.3e-31 109.0 5.9 2.3e-31 108.2 4.1 1.4 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region EF1G PF00647.14 CBK21757.2 - 6.5e-34 115.8 0.1 1.2e-33 114.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CBK21757.2 - 6e-15 55.0 0.0 6e-15 55.0 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBK21757.2 - 3.4e-11 43.1 0.0 6.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBK21757.2 - 6.4e-10 39.1 0.2 1.7e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBK21757.2 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBK21757.2 - 4.1e-08 33.6 1.1 1e-07 32.3 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBK21757.2 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pox_Ag35 PF03286.9 CBK21757.2 - 0.29 10.6 7.8 0.48 9.9 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SR-25 PF10500.4 CBK21757.2 - 0.56 9.6 11.1 0.84 9.0 7.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.3 CBK21757.2 - 1.7 7.3 7.8 2.5 6.7 5.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.1 CBK21757.2 - 8.2 4.8 9.6 7.3 5.0 5.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Tyr-DNA_phospho PF06087.7 CBK21758.2 - 1.4e-55 188.7 0.0 2.1e-55 188.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase tRNA-synt_1 PF00133.17 CBK21759.2 - 1.1e-52 178.8 0.0 4.6e-32 110.7 0.1 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CBK21759.2 - 5.3e-43 146.4 0.0 1.3e-42 145.1 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CBK21759.2 - 5.1e-25 87.9 0.0 4.2e-19 68.4 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBK21759.2 - 3.6e-08 33.3 0.0 8.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CBK21759.2 - 0.0017 17.2 0.0 0.0039 16.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CBK21759.2 - 0.017 14.2 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Adaptin_N PF01602.15 CBK21760.2 - 3.3e-07 28.9 0.0 4.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region NIF PF03031.13 CBK21762.2 - 2e-44 151.0 0.4 3.1e-44 150.4 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GCS PF03074.11 CBK21763.2 - 2.4e-140 467.8 1.2 2.9e-140 467.5 0.8 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase FliS PF02561.9 CBK21764.2 - 0.015 15.1 0.2 0.039 13.8 0.0 1.6 1 1 1 2 2 2 0 Flagellar protein FliS Aminotran_1_2 PF00155.16 CBK21765.2 - 3.2e-85 286.2 0.0 3.6e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Biotin_lipoyl PF00364.17 CBK21766.2 - 1.4e-18 66.2 2.4 1.6e-18 66.0 1.7 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 CBK21766.2 - 0.0033 16.6 0.4 0.081 12.0 0.0 1.9 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CBK21766.2 - 0.0043 16.6 1.8 0.13 11.9 0.0 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like Tbf5 PF06331.7 CBK21766.2 - 0.076 12.8 1.6 3.9 7.3 0.1 2.5 2 1 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Snf7 PF03357.16 CBK21767.2 - 3.8e-06 26.3 10.7 4.6e-06 26.1 7.4 1.1 1 0 0 1 1 1 1 Snf7 Syntaxin-18_N PF10496.4 CBK21767.2 - 0.0027 17.4 0.4 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.20 CBK21767.2 - 0.11 12.6 2.5 0.14 12.3 1.0 1.8 1 1 1 2 2 2 0 Syntaxin WD40 PF00400.27 CBK21768.2 - 4.1e-30 102.5 18.6 2.2e-08 33.6 0.1 5.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.9 CBK21768.2 - 3.3e-15 55.8 6.8 6.6e-15 54.9 4.7 1.5 1 0 0 1 1 1 1 Sof1-like domain Coatomer_WDAD PF04053.9 CBK21768.2 - 0.00085 18.2 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.6 CBK21768.2 - 0.001 17.9 0.3 0.26 10.0 0.0 2.6 1 1 1 3 3 3 2 Nup133 N terminal like Y_phosphatase PF00102.22 CBK21769.2 - 4.5e-09 36.0 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBK21769.2 - 3e-07 30.0 0.0 1.3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBK21769.2 - 0.00042 20.3 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBK21769.2 - 0.00059 20.1 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 CBK21769.2 - 0.021 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 CBK21769.2 - 0.074 12.4 0.7 0.17 11.2 0.2 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family He_PIG PF05345.7 CBK21771.2 - 2.9e-07 30.3 0.0 6.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Putative Ig domain CD34_antigen PF06365.7 CBK21771.2 - 0.1 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 CBK21771.2 - 0.16 12.3 0.7 9 6.7 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ELMO_CED12 PF04727.8 CBK21772.2 - 1e-28 100.0 0.1 1.2e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Rad50_zn_hook PF04423.9 CBK21772.2 - 0.034 13.5 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif hGDE_central PF14702.1 CBK21772.2 - 0.099 11.8 0.0 0.16 11.0 0.0 1.3 1 1 0 1 1 1 0 central domain of human glycogen debranching enzyme PPARgamma_N PF12577.3 CBK21773.2 - 0.094 13.0 0.2 0.095 13.0 0.2 1.2 1 1 0 1 1 1 0 PPAR gamma N-terminal region zf-DHHC PF01529.15 CBK21774.2 - 5e-19 68.3 9.6 5.6e-19 68.1 6.6 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase PSI PF01437.20 CBK21774.2 - 0.012 15.7 1.6 0.017 15.3 1.1 1.2 1 0 0 1 1 1 0 Plexin repeat NHL PF01436.16 CBK21774.2 - 0.021 14.7 1.0 0.038 13.9 0.7 1.5 1 0 0 1 1 1 0 NHL repeat Fer4_2 PF12797.2 CBK21774.2 - 0.22 11.4 0.6 0.22 11.4 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 CBK21774.2 - 2.3 7.9 5.3 0.5 10.0 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.18 CBK21775.2 - 1.9e-60 204.2 0.0 3.1e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK21775.2 - 2.3e-14 52.9 0.0 6.1e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CBK21775.2 - 6.8e-08 32.2 12.1 1.7e-07 30.9 8.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBK21775.2 - 1.6e-05 24.4 12.4 3.7e-05 23.2 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK21775.2 - 3.9e-05 23.2 14.1 9.8e-05 21.9 9.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK21775.2 - 0.00037 20.4 13.8 0.00037 20.4 9.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBK21775.2 - 0.0088 15.9 14.3 0.022 14.6 9.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING AsiA PF09010.5 CBK21775.2 - 0.026 14.3 0.4 0.081 12.8 0.3 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A zf-UDP PF14569.1 CBK21775.2 - 0.33 10.7 6.7 0.95 9.2 4.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.1 CBK21775.2 - 0.35 10.6 12.2 0.97 9.1 8.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.20 CBK21776.2 - 9.8e-56 188.7 0.1 1.3e-55 188.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21776.2 - 3.4e-23 82.0 0.0 6.4e-23 81.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK21776.2 - 2.3e-06 27.5 4.4 2.2e-05 24.2 0.0 3.2 2 2 0 3 3 3 1 Phosphotransferase enzyme family Mtc PF03820.12 CBK21777.2 - 3.7e-05 22.5 0.0 4.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier PEPCK_ATP PF01293.15 CBK21778.2 - 1.8e-05 23.5 0.0 2.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase LTXXQ PF07813.7 CBK21780.2 - 0.00078 19.8 4.4 0.0036 17.7 0.8 2.7 2 1 0 2 2 2 1 LTXXQ motif family protein API5 PF05918.6 CBK21782.2 - 1.2 7.4 5.4 1.5 7.2 3.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Dynamin_N PF00350.18 CBK21783.2 - 3.9e-16 59.3 0.1 5.4e-14 52.3 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBK21783.2 - 1.3e-10 41.2 0.0 3.5e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBK21783.2 - 0.00066 20.1 0.0 0.024 15.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CBK21783.2 - 0.0025 17.1 0.8 0.078 12.2 0.0 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.22 CBK21783.2 - 0.0042 17.3 0.0 0.51 10.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter DUF1273 PF06908.6 CBK21783.2 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) TcdA_TcdB_pore PF12920.2 CBK21783.2 - 0.18 9.6 0.0 0.24 9.2 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain MtrA PF04208.9 CBK21785.2 - 0.2 11.0 1.3 0.4 10.0 0.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Pantoate_ligase PF02569.10 CBK21786.2 - 1.8e-88 295.9 0.0 2e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_M24 PF00557.19 CBK21787.2 - 4.4e-49 166.8 0.0 6.6e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CBK21787.2 - 7.3e-06 25.7 10.6 1.8e-05 24.5 7.4 1.7 1 0 0 1 1 1 1 MYND finger WW PF00397.21 CBK21788.2 - 3.4e-07 30.0 8.0 5.6e-07 29.3 5.5 1.3 1 0 0 1 1 1 1 WW domain Prp31_C PF09785.4 CBK21788.2 - 0.026 14.9 0.2 0.031 14.6 0.2 1.2 1 0 0 1 1 1 0 Prp31 C terminal domain TEX19 PF15553.1 CBK21788.2 - 0.13 12.1 1.1 0.16 11.7 0.8 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Adap_comp_sub PF00928.16 CBK21789.2 - 4.1e-57 193.2 0.1 5.7e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK21789.2 - 4.2e-06 26.5 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Lung_7-TM_R PF06814.8 CBK21790.2 - 8.2e-49 166.1 23.0 1e-48 165.8 15.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBK21790.2 - 8e-06 25.2 15.7 8e-06 25.2 10.9 1.9 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Inhibitor_I71 PF12628.2 CBK21790.2 - 0.071 12.7 0.2 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor LEP503 PF15221.1 CBK21790.2 - 0.27 10.9 1.9 0.59 9.8 1.3 1.5 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 RhoGAP PF00620.22 CBK21791.2 - 2e-21 76.1 0.0 1.4e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain MyTH4 PF00784.12 CBK21791.2 - 6.5e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain Glyco_hydro_3 PF00933.16 CBK21792.2 - 2.2e-29 102.4 0.0 2.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CBK21793.2 - 2.7e-43 148.1 0.0 3.5e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CBK21793.2 - 5.6e-14 51.8 0.0 3.7e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 Fibronectin type III-like domain Peptidase_S6 PF02395.11 CBK21793.2 - 0.069 11.2 0.0 0.53 8.3 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin A1 protease Glyco_tran_WecB PF03808.8 CBK21793.2 - 0.097 12.0 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family CARDB PF07705.6 CBK21793.2 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 CARDB TPK_catalytic PF04263.11 CBK21793.2 - 0.16 11.5 0.0 0.64 9.6 0.0 1.9 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain UCH PF00443.24 CBK21794.2 - 1.8e-14 53.5 0.1 3.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LRR_4 PF12799.2 CBK21795.2 - 0.013 15.1 0.1 0.88 9.2 0.0 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK21795.2 - 0.02 14.6 2.8 4.6 7.0 0.3 2.8 2 1 0 2 2 2 0 Leucine rich repeat MORN_2 PF07661.8 CBK21795.2 - 0.24 11.5 9.9 7.7 6.9 0.5 3.9 3 0 0 3 3 3 0 MORN repeat variant LRR_6 PF13516.1 CBK21795.2 - 0.74 10.0 6.3 21 5.5 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat RmlD_sub_bind PF04321.12 CBK21796.2 - 5.4e-16 58.3 0.0 1.3e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 CBK21796.2 - 1.1e-15 57.7 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBK21796.2 - 4e-06 25.7 0.3 1.2e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK21796.2 - 0.00029 19.8 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CBK21796.2 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CBK21796.2 - 0.0049 16.7 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CBK21796.2 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Proteasome PF00227.21 CBK21797.2 - 1.6e-51 174.2 0.1 2.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK21797.2 - 2.3e-10 39.6 0.0 3.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SICA_C PF12879.2 CBK21797.2 - 0.0058 16.4 0.1 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 SICA C-terminal inner membrane domain HEAT PF02985.17 CBK21798.2 - 1.1e-07 31.2 0.6 0.16 12.1 0.0 5.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CBK21798.2 - 1.2e-06 28.6 0.0 0.00097 19.3 0.0 3.2 3 2 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 CBK21798.2 - 0.0047 17.3 0.0 18 5.9 0.0 3.8 3 1 1 4 4 4 2 HEAT-like repeat DUF1981 PF09324.5 CBK21798.2 - 0.039 13.4 0.9 15 5.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) CTDII PF01556.13 CBK21799.2 - 1.6e-33 114.4 3.6 4.6e-24 84.1 0.2 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CBK21799.2 - 7e-25 86.5 2.4 1.3e-24 85.7 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBK21799.2 - 5.5e-12 45.5 15.3 9.5e-12 44.7 10.6 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-TFIIB PF13453.1 CBK21799.2 - 0.37 10.0 11.8 1.9 7.7 1.9 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.14 CBK21799.2 - 1.3 8.7 11.0 0.66 9.6 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CBK21799.2 - 2.3 8.0 15.6 5.7 6.8 3.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Ogr_Delta PF04606.7 CBK21799.2 - 5.5 6.7 9.7 0.61 9.7 0.1 3.4 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger MFS_1 PF07690.11 CBK21800.2 - 0.0019 17.0 0.4 0.0021 16.8 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CBK21801.2 - 1.4e-13 50.3 11.8 1.7e-13 50.0 8.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK21801.2 - 9.2e-09 34.3 9.2 6.1e-08 31.6 6.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Myb_DNA-binding PF00249.26 CBK21802.2 - 0.004 17.1 0.1 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain GNAT_acetyltr_2 PF13718.1 CBK21803.2 - 5.8e-77 257.4 0.0 1.1e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CBK21803.2 - 2.6e-61 206.3 0.0 5.2e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CBK21803.2 - 5.6e-36 122.1 0.0 1.6e-35 120.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CBK21803.2 - 1.7e-22 79.4 1.5 3.5e-22 78.4 0.3 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CBK21803.2 - 0.00082 19.4 0.2 0.0072 16.4 0.2 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Auxin_resp PF06507.8 CBK21803.2 - 0.017 14.9 0.2 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Auxin response factor Acetyltransf_1 PF00583.19 CBK21803.2 - 0.026 14.5 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CRM1_C PF08767.6 CBK21804.2 - 0.0027 16.6 0.1 0.0069 15.3 0.1 1.6 1 0 0 1 1 1 1 CRM1 C terminal FAD_binding_1 PF00667.15 CBK21807.2 - 2.4e-55 187.3 0.0 3.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBK21807.2 - 3.1e-22 79.1 0.1 5.1e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CBK21807.2 - 6.3e-11 42.8 0.0 1.3e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DNA_pol_B_exo1 PF03104.14 CBK21808.2 - 6.1e-08 31.9 1.7 6.3e-08 31.8 0.1 1.8 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CBK21809.2 - 4.1e-73 246.7 0.0 5.1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 CBK21809.2 - 0.016 15.1 0.1 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta He_PIG PF05345.7 CBK21810.2 - 0.00061 19.7 0.4 0.0016 18.3 0.3 1.8 1 0 0 1 1 1 1 Putative Ig domain Rifin_STEVOR PF02009.11 CBK21810.2 - 0.0042 16.7 1.7 0.0062 16.2 1.2 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 CBK21810.2 - 0.031 13.9 0.3 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 CBK21810.2 - 0.054 13.5 0.5 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HemY_N PF07219.8 CBK21810.2 - 0.43 10.1 2.1 0.73 9.4 1.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Protocadherin PF08374.6 CBK21810.2 - 0.8 9.3 3.1 1.5 8.3 2.2 1.4 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 CBK21810.2 - 1.2 9.6 4.9 2.1 8.7 3.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 CBK21810.2 - 1.5 8.1 6.6 3.2 7.1 4.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FAM117 PF15388.1 CBK21811.2 - 0.002 17.4 0.1 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Protein Family FAM117 Phi-29_GP3 PF05435.6 CBK21811.2 - 0.015 14.5 4.8 0.19 10.9 0.2 2.3 1 1 1 2 2 2 0 Phi-29 DNA terminal protein GP3 FH2 PF02181.18 CBK21812.2 - 5e-44 150.7 2.4 1.3e-43 149.3 1.7 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CBK21812.2 - 2.4e-15 56.4 2.7 2.4e-15 56.4 1.8 2.1 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF2360 PF10152.4 CBK21812.2 - 5.1e-14 52.7 3.7 2.8e-08 34.1 0.0 3.4 3 0 0 3 3 3 2 Predicted coiled-coil domain-containing protein (DUF2360) Drf_GBD PF06371.8 CBK21812.2 - 7.8e-07 28.6 0.1 7.8e-07 28.6 0.1 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain FAD_binding_2 PF00890.19 CBK21813.2 - 2e-121 405.7 3.2 2.7e-121 405.3 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBK21813.2 - 7.7e-48 161.5 1.8 1.1e-47 161.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBK21813.2 - 1.2e-06 27.7 0.1 8.6e-06 24.8 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBK21813.2 - 1.4e-06 27.6 0.2 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CBK21813.2 - 2.6e-05 24.2 1.4 0.00034 20.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBK21813.2 - 4.5e-05 22.4 0.9 0.0025 16.7 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CBK21813.2 - 0.00027 20.1 0.2 0.00045 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CBK21813.2 - 0.017 15.4 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 CBK21813.2 - 0.022 13.2 1.5 0.038 12.4 0.2 2.0 3 0 0 3 3 3 0 HI0933-like protein DNA_pol_B_2 PF03175.8 CBK21814.2 - 7.1e-09 34.8 9.8 0.0019 16.9 0.1 3.5 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral Peptidase_C13 PF01650.13 CBK21815.2 - 6.1e-95 317.3 0.1 8.1e-95 316.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF896 PF05979.7 CBK21815.2 - 0.12 11.9 1.9 0.42 10.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) NIF PF03031.13 CBK21816.2 - 1.4e-47 161.2 0.3 2e-47 160.8 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBK21816.2 - 0.029 14.5 0.1 0.28 11.3 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Ribosomal_S3Ae PF01015.13 CBK21817.2 - 3.2e-73 245.2 4.3 4.9e-73 244.6 3.0 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Metallophos PF00149.23 CBK21817.2 - 1.8e-05 24.2 0.3 0.00018 20.9 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SUI1 PF01253.17 CBK21817.2 - 0.0026 17.5 0.1 0.0076 16.0 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 AlcCBM31 PF11606.3 CBK21817.2 - 0.055 13.4 0.2 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein Abhydro_lipase PF04083.11 CBK21817.2 - 0.11 11.8 0.0 0.33 10.3 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region IPPT PF01715.12 CBK21818.2 - 6.8e-58 195.6 0.2 1e-57 195.0 0.2 1.2 1 0 0 1 1 1 1 IPP transferase LXG PF04740.7 CBK21818.2 - 0.032 14.0 0.2 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily CAS_CSE1 PF03378.10 CBK21818.2 - 0.1 10.9 0.1 0.2 9.9 0.1 1.5 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus BLOC1_2 PF10046.4 CBK21819.2 - 4.4e-06 26.7 7.0 0.00078 19.5 1.4 2.6 2 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 CBK21819.2 - 0.0022 17.2 6.2 0.019 14.1 0.6 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Gcd10p PF04189.8 CBK21819.2 - 0.0044 16.1 0.4 0.006 15.7 0.1 1.4 2 0 0 2 2 2 1 Gcd10p family IncA PF04156.9 CBK21819.2 - 0.0057 16.2 10.6 0.019 14.6 3.0 2.1 1 1 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 CBK21819.2 - 0.0073 15.5 4.1 0.067 12.3 0.4 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF1664 PF07889.7 CBK21819.2 - 0.0082 15.9 3.1 0.66 9.7 0.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Spectrin PF00435.16 CBK21819.2 - 0.0097 16.1 2.0 0.062 13.5 0.2 2.3 2 0 0 2 2 2 1 Spectrin repeat DUF948 PF06103.6 CBK21819.2 - 0.011 15.5 3.7 3 7.7 0.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 CBK21819.2 - 0.021 14.7 8.5 6.5 6.7 0.0 3.2 1 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF869 PF05911.6 CBK21819.2 - 0.022 13.0 5.9 0.025 12.8 4.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Borrelia_lipo_1 PF05714.6 CBK21819.2 - 0.031 13.3 8.1 0.15 11.1 0.3 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein NPV_P10 PF05531.7 CBK21819.2 - 0.04 14.1 2.1 4.9 7.4 0.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DELLA PF12041.3 CBK21819.2 - 0.04 13.5 1.9 0.21 11.2 0.1 2.6 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal Laminin_I PF06008.9 CBK21819.2 - 0.043 13.1 6.2 0.078 12.2 4.3 1.4 1 1 0 1 1 1 0 Laminin Domain I DHC_N2 PF08393.8 CBK21819.2 - 0.056 11.9 5.8 0.49 8.8 4.0 2.1 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 TBPIP PF07106.8 CBK21819.2 - 0.077 12.5 9.3 0.18 11.3 2.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rootletin PF15035.1 CBK21819.2 - 0.085 12.8 2.7 0.12 12.3 1.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FadA PF09403.5 CBK21819.2 - 0.14 12.1 5.3 7.5 6.5 0.0 3.0 1 1 1 3 3 3 0 Adhesion protein FadA FlaC_arch PF05377.6 CBK21819.2 - 0.15 11.9 9.0 1.6 8.7 0.5 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Cytochrom_B562 PF07361.6 CBK21819.2 - 0.15 12.4 3.0 0.86 10.0 0.2 2.8 2 2 1 3 3 3 0 Cytochrome b562 DUF972 PF06156.8 CBK21819.2 - 0.18 12.1 7.9 1.3 9.4 0.2 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) YtxH PF12732.2 CBK21819.2 - 0.21 11.9 1.2 0.54 10.6 0.7 2.0 1 1 0 1 1 1 0 YtxH-like protein Seryl_tRNA_N PF02403.17 CBK21819.2 - 0.21 11.5 4.1 7.2 6.6 0.2 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 CBK21819.2 - 0.36 10.5 10.9 1.6 8.4 0.5 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 CBK21819.2 - 0.4 9.0 9.5 1.5 7.2 1.8 1.9 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.8 CBK21819.2 - 0.75 9.1 5.8 1.9 7.8 0.9 2.3 1 1 1 2 2 2 0 fzo-like conserved region Transposase_22 PF02994.9 CBK21819.2 - 0.79 8.1 6.5 4.3 5.7 4.5 1.9 1 1 0 1 1 1 0 L1 transposable element LOH1CR12 PF10158.4 CBK21819.2 - 1.2 8.9 5.5 2.1 8.1 0.1 2.7 1 1 1 3 3 3 0 Tumour suppressor protein Phage_GP20 PF06810.6 CBK21819.2 - 1.2 8.5 4.4 1.5 8.2 0.4 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.7 CBK21819.2 - 3.3 8.1 6.3 20 5.6 0.5 3.2 3 1 0 3 3 3 0 SlyX Snapin_Pallidin PF14712.1 CBK21819.2 - 3.9 7.8 7.3 12 6.3 1.4 2.9 2 2 0 2 2 2 0 Snapin/Pallidin Vps51 PF08700.6 CBK21819.2 - 5.6 6.8 8.3 4.4 7.1 0.2 3.6 3 2 0 3 3 3 0 Vps51/Vps67 TSC22 PF01166.13 CBK21819.2 - 7.1 6.6 8.2 1.4 8.9 0.3 3.3 3 2 2 5 5 4 0 TSC-22/dip/bun family Lung_7-TM_R PF06814.8 CBK21820.2 - 3.9e-21 75.2 2.9 5.4e-21 74.8 2.0 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF432 PF04254.8 CBK21820.2 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Sec62 PF03839.11 CBK21820.2 - 0.019 14.3 4.5 0.037 13.4 3.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF986 PF06173.7 CBK21820.2 - 0.1 12.3 1.5 0.24 11.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF986) Transaldolase PF00923.14 CBK21823.2 - 2.4e-95 318.9 0.0 2.7e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase CTNNBL PF08216.6 CBK21824.2 - 1.5e-23 82.4 1.5 1.5e-23 82.4 1.0 3.3 4 1 0 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear PLU-1 PF08429.6 CBK21824.2 - 0.087 11.7 3.5 0.075 11.9 0.7 1.9 2 0 0 2 2 2 0 PLU-1-like protein Myb_DNA-binding PF00249.26 CBK21825.2 - 5.1e-13 48.8 1.1 7.3e-13 48.3 0.7 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK21825.2 - 2.5e-05 24.2 0.9 3.7e-05 23.7 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain KKLCAg1 PF15204.1 CBK21825.2 - 0.27 11.3 1.3 2.9 7.9 0.1 2.1 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Ribosomal_S4e PF00900.15 CBK21826.2 - 1.1e-28 98.6 0.7 2.6e-28 97.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.24 CBK21826.2 - 0.0004 19.9 2.0 0.0004 19.9 1.4 3.4 4 0 0 4 4 4 1 KOW motif S4 PF01479.20 CBK21826.2 - 0.012 15.0 0.3 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 S4 domain Clat_adaptor_s PF01217.15 CBK21827.2 - 4.4e-17 62.1 1.9 5.1e-17 61.9 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glycos_transf_4 PF00953.16 CBK21828.2 - 1e-34 119.6 3.7 1e-34 119.6 2.6 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF3392 PF11872.3 CBK21828.2 - 0.0017 18.2 1.4 0.0028 17.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3392) DUF4236 PF14020.1 CBK21829.2 - 0.42 10.7 5.2 0.22 11.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) AAA_5 PF07728.9 CBK21830.2 - 1.2e-56 190.3 0.0 1.7e-13 50.5 0.0 6.7 6 0 0 6 6 6 5 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK21830.2 - 1.6e-14 54.1 0.7 0.044 13.9 0.1 6.8 6 2 0 6 6 4 3 AAA domain AAA_14 PF13173.1 CBK21830.2 - 4.5e-14 52.4 0.0 0.004 17.0 0.0 5.6 4 0 0 4 4 4 3 AAA domain AAA_3 PF07726.6 CBK21830.2 - 2e-12 46.8 0.0 2.6e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBK21830.2 - 2.4e-07 30.9 0.6 0.051 13.7 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBK21830.2 - 3.5e-07 29.8 0.0 0.0066 15.9 0.0 4.5 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.1 CBK21830.2 - 3.7e-05 23.8 0.4 1 9.3 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain AAA_33 PF13671.1 CBK21830.2 - 5.7e-05 23.0 0.0 0.32 10.8 0.0 4.6 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 CBK21830.2 - 0.0037 18.0 0.1 7.7 7.3 0.0 5.7 6 0 0 6 6 5 1 AAA domain MobB PF03205.9 CBK21830.2 - 0.004 16.8 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBK21830.2 - 0.023 14.4 0.0 7 6.4 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBK21830.2 - 0.033 13.6 0.1 15 4.9 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.7 CBK21830.2 - 0.067 12.8 0.0 59 3.2 0.0 4.2 4 0 0 4 4 4 0 NACHT domain AAA_29 PF13555.1 CBK21830.2 - 0.098 12.1 0.0 9.5 5.8 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CBK21830.2 - 0.19 11.2 0.0 46 3.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain KfrA_N PF11740.3 CBK21830.2 - 4.4 7.7 3.7 9.7 6.6 2.6 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term XPG_I PF00867.13 CBK21831.2 - 6e-24 83.9 0.1 1.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBK21831.2 - 4e-15 55.9 0.0 6.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CBK21831.2 - 0.001 18.6 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing DUF1232 PF06803.7 CBK21831.2 - 0.043 13.2 2.1 0.11 11.9 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) DUF2480 PF10652.4 CBK21831.2 - 0.052 13.1 0.1 0.63 9.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2480) Adaptin_N PF01602.15 CBK21832.2 - 5.6e-148 493.5 15.4 6.6e-148 493.2 10.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK21832.2 - 1.8e-26 93.1 5.9 8e-24 84.4 0.2 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK21832.2 - 3.5e-20 72.0 3.1 2.9e-08 33.8 0.0 6.5 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.17 CBK21832.2 - 4.9e-11 41.7 7.5 0.0039 17.1 0.0 7.5 8 0 0 8 8 7 2 HEAT repeat Cnd3 PF12719.2 CBK21832.2 - 6.9e-07 28.5 1.6 0.0003 19.8 0.0 3.1 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 CBK21832.2 - 1.7e-06 27.6 0.7 0.32 10.8 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBK21832.2 - 0.0002 21.7 1.8 5.2 7.6 0.0 5.6 6 1 0 6 6 4 1 HEAT-like repeat CLASP_N PF12348.3 CBK21832.2 - 0.00023 20.6 2.0 0.53 9.5 0.0 3.8 2 1 1 3 3 3 1 CLASP N terminal FANCI_S3 PF14677.1 CBK21832.2 - 0.0067 15.8 0.4 0.061 12.7 0.1 2.5 2 0 0 2 2 2 1 FANCI solenoid 3 UNC45-central PF11701.3 CBK21832.2 - 0.03 13.9 3.0 0.99 9.0 0.0 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.1 CBK21832.2 - 0.058 13.3 2.2 1.5 8.7 0.1 3.9 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N PF14664.1 CBK21832.2 - 0.2 10.2 6.8 0.39 9.2 0.7 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Sec7_N PF12783.2 CBK21832.2 - 0.26 10.6 4.3 0.12 11.8 0.3 2.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.3 CBK21832.2 - 0.66 9.9 4.5 10 6.0 0.0 4.3 4 1 0 4 4 4 0 V-ATPase subunit H FANCI_S2 PF14676.1 CBK21832.2 - 0.71 9.7 4.4 8 6.3 0.1 3.9 3 2 1 4 4 4 0 FANCI solenoid 2 CobT PF06213.7 CBK21832.2 - 3 6.8 34.8 6.3 5.8 24.1 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 CBK21832.2 - 4.1 5.5 12.3 7.7 4.6 8.5 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CBK21832.2 - 7.5 4.3 47.5 2.5 5.9 30.4 2.1 2 0 0 2 2 2 0 Nop14-like family ATP-grasp_5 PF13549.1 CBK21833.2 - 1.4e-79 266.3 0.9 2e-79 265.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CBK21833.2 - 5.6e-57 191.2 0.6 1.9e-56 189.5 0.4 2.0 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK21833.2 - 1.3e-23 83.3 3.8 7.9e-23 80.8 0.1 3.5 4 0 0 4 4 4 1 CoA binding domain CoA_binding PF02629.14 CBK21833.2 - 2.3e-15 56.8 0.7 9.4e-15 54.9 0.1 2.5 2 0 0 2 2 1 1 CoA binding domain Acetyltransf_1 PF00583.19 CBK21833.2 - 3.9e-07 30.0 0.1 9e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ATP-grasp_4 PF13535.1 CBK21833.2 - 9.9e-06 25.4 0.2 0.0012 18.6 0.0 3.8 4 1 1 5 5 5 1 ATP-grasp domain Acetyltransf_3 PF13302.1 CBK21833.2 - 3.5e-05 24.0 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK21833.2 - 3.5e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBK21833.2 - 4.7e-05 23.1 1.5 0.0014 18.4 0.1 3.1 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase ATP-grasp_2 PF08442.5 CBK21833.2 - 9.7e-05 21.8 0.1 0.00027 20.3 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_10 PF13673.1 CBK21833.2 - 0.00042 20.4 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBK21833.2 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.12 CBK21833.2 - 0.0094 15.2 0.1 0.028 13.7 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CBK21833.2 - 0.024 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Pkinase PF00069.20 CBK21834.2 - 2e-28 99.2 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21834.2 - 6.3e-11 41.8 0.0 1.9e-10 40.2 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBK21834.2 - 0.013 14.6 0.0 0.071 12.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBK21834.2 - 0.035 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Bac_export_2 PF01312.14 CBK21836.2 - 0.45 9.3 5.0 0.66 8.7 2.8 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF3671 PF12420.3 CBK21836.2 - 7.8 6.5 8.6 14 5.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function adh_short PF00106.20 CBK21837.2 - 2.6e-19 69.7 0.0 3.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBK21837.2 - 6.3e-09 35.7 0.1 9.2e-09 35.2 0.1 1.3 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 CBK21837.2 - 0.012 14.8 0.2 0.055 12.7 0.2 1.8 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 CBK21837.2 - 0.014 15.3 0.1 0.023 14.7 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 CBK21837.2 - 0.062 12.7 0.1 0.085 12.2 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAR2 PF05282.6 CBK21838.2 - 7.1e-51 173.2 13.8 7.9e-29 100.7 0.3 2.0 1 1 1 2 2 2 2 AAR2 protein Rep_3 PF01051.16 CBK21838.2 - 0.2 11.2 5.4 3.3 7.2 0.3 2.1 2 0 0 2 2 2 0 Initiator Replication protein MORN PF02493.15 CBK21839.2 - 6.5e-07 28.7 24.4 0.019 14.6 0.9 8.0 9 0 0 9 9 9 3 MORN repeat LRR_4 PF12799.2 CBK21839.2 - 8.4e-05 22.1 0.7 0.81 9.3 0.0 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK21839.2 - 0.0037 16.9 0.6 0.32 10.7 0.1 2.8 2 1 0 2 2 2 1 Leucine rich repeat Pro_isomerase PF00160.16 CBK21840.2 - 5.6e-22 78.6 0.0 1.1e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PIGA PF08288.7 CBK21841.2 - 7.8e-24 83.8 0.9 1.7e-23 82.8 0.6 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CBK21841.2 - 4.7e-15 55.4 0.0 8.6e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBK21841.2 - 3.1e-11 43.3 0.2 1.1e-10 41.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CBK21841.2 - 3.5e-08 33.6 0.0 7.3e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBK21841.2 - 1.5e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 CBK21841.2 - 0.00061 19.6 0.2 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CBK21841.2 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CBK21841.2 - 0.049 13.1 0.4 5.6 6.3 0.0 2.2 1 1 1 2 2 2 0 Starch synthase catalytic domain Actin PF00022.14 CBK21842.2 - 8.1e-10 37.6 0.0 0.00033 19.2 0.0 2.1 1 1 1 2 2 2 2 Actin BRO1 PF03097.13 CBK21843.2 - 4.5e-20 71.7 0.0 5.2e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain Toprim_2 PF13155.1 CBK21843.2 - 0.081 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Toprim-like ALIX_LYPXL_bnd PF13949.1 CBK21844.2 - 1.7e-12 46.9 7.8 3.6e-10 39.2 2.2 2.5 1 1 1 2 2 2 2 ALIX V-shaped domain binding to HIV Snapin_Pallidin PF14712.1 CBK21844.2 - 0.0026 18.0 0.9 0.0026 18.0 0.6 3.2 3 1 1 4 4 4 1 Snapin/Pallidin Methyltransf_22 PF13383.1 CBK21844.2 - 0.027 13.9 0.1 0.065 12.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain ING PF12998.2 CBK21844.2 - 0.11 12.7 2.1 0.36 11.1 0.4 2.6 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PAP_RNA-bind PF04926.10 CBK21844.2 - 0.15 11.5 1.6 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Tup_N PF08581.5 CBK21844.2 - 1 9.6 5.9 0.15 12.3 0.2 2.5 3 0 0 3 3 3 0 Tup N-terminal Syntaxin-6_N PF09177.6 CBK21844.2 - 2.1 8.8 7.4 4.7 7.6 0.1 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Methyltransf_5 PF01795.14 CBK21845.2 - 1.7e-53 181.9 0.0 2e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family PseudoU_synth_2 PF00849.17 CBK21846.2 - 9.7e-32 110.0 0.0 1.4e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 CBK21846.2 - 7.6e-06 25.2 0.1 2.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.1 CBK21846.2 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin ThiS PF02597.15 CBK21846.2 - 0.02 15.3 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 ThiS family TGS PF02824.16 CBK21846.2 - 0.059 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 TGS domain Hist_deacetyl PF00850.14 CBK21848.2 - 3.6e-18 65.9 0.0 6.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain PHD PF00628.24 CBK21848.2 - 1.9e-06 27.4 7.0 4.2e-06 26.3 4.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK21848.2 - 0.018 14.3 3.8 0.032 13.5 2.6 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 CBK21849.2 - 1.1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21849.2 - 2.3e-31 108.8 0.0 3.4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21849.2 - 0.0018 17.2 0.0 0.0035 16.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK21849.2 - 0.0032 16.5 0.0 0.0073 15.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK21849.2 - 0.0049 16.6 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family NTP_transferase PF00483.18 CBK21850.2 - 2.8e-43 148.0 0.0 3.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBK21850.2 - 3.4e-11 42.1 1.1 1.3e-06 27.6 0.5 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CBK21850.2 - 3.7e-08 33.5 0.0 5.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CBK21850.2 - 2.5e-06 26.9 7.7 5e-06 25.9 1.7 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CBK21850.2 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 1 0 1 1 1 0 Cytidylyltransferase Aminotran_1_2 PF00155.16 CBK21851.2 - 1.1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK21851.2 - 0.0025 17.0 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase DUF563 PF04577.9 CBK21852.2 - 1.9e-16 60.6 0.0 2.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Aldedh PF00171.17 CBK21853.2 - 3.7e-80 269.5 0.0 4.1e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CBK21853.2 - 0.016 13.9 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Syntaxin PF00804.20 CBK21853.2 - 0.038 14.1 0.1 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 Syntaxin mRNA_cap_enzyme PF01331.14 CBK21854.2 - 9.7e-47 159.1 0.2 1.4e-46 158.6 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CBK21854.2 - 2.7e-08 33.4 0.0 1.3e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Mur_ligase_M PF08245.7 CBK21855.2 - 2.5e-07 30.9 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 2 Mur ligase middle domain mit_SMPDase PF14724.1 CBK21856.2 - 0.14 9.9 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase AhpC-TSA PF00578.16 CBK21857.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK21857.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK21857.2 - 2.2e-12 46.4 0.0 4.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.20 CBK21858.2 - 1.6e-13 50.4 0.1 1.7e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21858.2 - 1.6e-06 27.3 0.0 1.9e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBK21859.2 - 3e-18 65.9 0.0 5.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21859.2 - 3.8e-12 45.8 0.0 1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase E3_UbLigase_R4 PF13764.1 CBK21859.2 - 0.0046 14.9 3.3 0.0065 14.4 2.3 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DUF1765 PF08578.5 CBK21859.2 - 0.046 13.7 0.2 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) HECT PF00632.20 CBK21860.2 - 8.4e-67 225.5 0.0 1.8e-66 224.4 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.8 CBK21861.2 - 9.9e-17 60.6 6.8 1.6e-16 60.0 4.7 1.3 1 0 0 1 1 1 1 Mib_herc2 MORN_2 PF07661.8 CBK21862.2 - 0.11 12.5 4.2 7.4 6.9 0.5 3.1 2 0 0 2 2 2 0 MORN repeat variant AhpC-TSA PF00578.16 CBK21864.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK21864.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK21864.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_pol_B_2 PF03175.8 CBK21865.2 - 3e-07 29.4 10.9 0.0011 17.7 0.4 3.5 3 1 0 3 3 3 3 DNA polymerase type B, organellar and viral AhpC-TSA PF00578.16 CBK21867.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK21867.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK21867.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Mo25 PF08569.6 CBK21868.2 - 2.7e-38 131.8 7.3 4.9e-38 130.9 5.0 1.4 1 1 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.9 CBK21868.2 - 0.056 12.5 0.2 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H CorA PF01544.13 CBK21870.2 - 3.7 6.5 16.5 0.071 12.1 5.0 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Nfu_N PF08712.6 CBK21871.2 - 3.1e-25 87.5 0.2 9.7e-25 86.0 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CBK21871.2 - 7.8e-20 70.4 0.0 1.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Upf2 PF04050.9 CBK21871.2 - 0.0081 15.9 4.9 0.51 10.0 3.2 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Med10 PF09748.4 CBK21871.2 - 0.0096 15.7 1.3 0.02 14.7 0.9 1.5 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FPL PF09758.4 CBK21873.2 - 1e-37 129.1 8.9 1.3e-37 128.8 6.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein RIX1 PF08167.7 CBK21873.2 - 0.026 14.1 1.2 0.039 13.6 0.8 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis RPEL PF02755.10 CBK21874.2 - 0.015 14.6 7.4 0.38 10.1 0.2 3.7 3 0 0 3 3 3 0 RPEL repeat DUF448 PF04296.8 CBK21874.2 - 0.03 13.9 0.7 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF448) PaaSYMP PF14738.1 CBK21874.2 - 0.49 10.1 4.8 0.96 9.1 0.2 2.3 1 1 1 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 ER PF01133.12 CBK21876.2 - 7.2e-24 83.4 0.1 1.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary PTPA PF03095.10 CBK21877.2 - 2.1e-72 243.8 0.0 2.5e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Syntaxin-6_N PF09177.6 CBK21878.2 - 4.2e-12 46.3 2.3 4.2e-12 46.3 1.6 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CBK21878.2 - 1.2e-11 44.0 5.8 1.2e-11 44.0 4.0 2.8 3 0 0 3 3 3 1 SNARE domain TBPIP PF07106.8 CBK21878.2 - 0.012 15.2 2.6 0.012 15.2 1.8 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 CBK21878.2 - 0.041 14.0 7.8 1.7 8.8 0.5 2.8 1 1 0 2 2 2 0 Syntaxin Lzipper-MIP1 PF14389.1 CBK21878.2 - 0.073 13.1 2.1 0.1 12.7 0.1 2.2 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Orbi_VP5 PF00901.12 CBK21878.2 - 0.084 11.0 4.6 0.07 11.3 2.2 1.5 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 LXG PF04740.7 CBK21878.2 - 0.088 12.5 6.6 0.1 12.4 2.4 2.2 2 1 0 2 2 2 0 LXG domain of WXG superfamily FliJ PF02050.11 CBK21878.2 - 0.11 12.5 8.7 0.076 13.0 1.2 3.0 1 1 2 3 3 3 0 Flagellar FliJ protein Baculo_PEP_C PF04513.7 CBK21878.2 - 0.24 11.2 2.9 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.19 CBK21878.2 - 0.35 10.5 4.2 0.35 10.5 0.7 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Use1 PF09753.4 CBK21878.2 - 0.36 10.2 10.3 0.77 9.1 7.1 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 Atg14 PF10186.4 CBK21878.2 - 0.45 9.4 10.0 0.32 9.8 2.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 CBK21878.2 - 0.48 10.8 4.0 4.3 7.7 0.7 3.4 2 1 1 3 3 3 0 SlyX TBCA PF02970.11 CBK21878.2 - 0.6 10.2 7.8 0.2 11.7 1.3 2.8 1 1 0 2 2 2 0 Tubulin binding cofactor A NPV_P10 PF05531.7 CBK21878.2 - 1.1 9.5 4.2 3.2 8.0 0.7 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBK21878.2 - 3.4 7.4 6.7 4 7.2 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 CBK21878.2 - 3.5 6.4 10.6 1.9 7.3 5.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Med2 PF11214.3 CBK21878.2 - 3.8 7.5 8.4 0.51 10.4 2.2 2.2 2 1 0 2 2 2 0 Mediator complex subunit 2 Cep57_CLD_2 PF14197.1 CBK21878.2 - 5.2 7.0 8.9 1.1 9.2 0.3 3.6 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 CBK21878.2 - 7.9 6.5 9.0 1.1 9.2 0.1 3.4 3 1 0 3 3 3 0 bZIP transcription factor TMF_DNA_bd PF12329.3 CBK21878.2 - 8.5 6.2 9.6 10 6.0 0.4 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding MMS19_N PF14500.1 CBK21880.2 - 8.2e-24 84.2 0.1 1.5e-23 83.3 0.0 1.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 CBK21880.2 - 2e-05 24.2 0.3 0.021 14.8 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CBK21880.2 - 3.5e-05 23.9 0.2 0.11 12.7 0.1 2.9 2 0 0 2 2 2 2 HEAT repeats Adaptin_N PF01602.15 CBK21880.2 - 0.085 11.1 0.1 2.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Nuc_sug_transp PF04142.10 CBK21881.2 - 1e-31 109.8 17.7 2.7e-31 108.5 12.3 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 CBK21881.2 - 3.3e-06 26.8 26.0 0.0019 17.8 8.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBK21881.2 - 0.00035 20.6 19.5 0.015 15.3 4.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBK21881.2 - 0.013 15.6 2.3 0.013 15.6 1.6 2.5 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Lactamase_B PF00753.22 CBK21882.2 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Zip PF02535.17 CBK21883.2 - 1e-07 31.3 5.1 0.00014 20.9 1.4 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter DUF401 PF04165.7 CBK21883.2 - 0.16 10.9 3.9 0.19 10.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) Zip PF02535.17 CBK21884.2 - 1e-20 74.0 0.6 1.2e-20 73.7 0.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBK21884.2 - 0.0023 17.0 0.1 0.004 16.2 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase UPF0060 PF02694.10 CBK21884.2 - 0.19 11.7 1.2 0.24 11.4 0.3 1.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Zip PF02535.17 CBK21885.2 - 4.4e-19 68.6 0.2 5.2e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.15 CBK21885.2 - 0.0022 17.0 0.2 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Zip PF02535.17 CBK21886.2 - 3.4e-07 29.5 7.3 0.00045 19.3 0.3 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Ribosomal_L11 PF00298.14 CBK21887.2 - 3e-24 84.9 0.1 4.9e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CBK21887.2 - 1.4e-20 72.4 0.1 1.2e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ras PF00071.17 CBK21888.2 - 1.1e-49 167.9 0.0 1.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK21888.2 - 1.6e-12 47.9 0.0 2.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK21888.2 - 1.7e-05 24.1 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Helicase_C PF00271.26 CBK21889.2 - 5.7e-19 67.7 0.8 1.2e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK21889.2 - 9e-06 25.2 0.0 2.2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3987 PF13148.1 CBK21889.2 - 0.021 13.3 0.1 0.1 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF3052 PF11253.3 CBK21889.2 - 0.049 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) XG_FTase PF03254.8 CBK21890.2 - 4e-06 25.6 0.3 0.00053 18.6 0.1 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.6 CBK21890.2 - 0.00015 20.4 0.0 0.00022 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.4 CBK21890.2 - 0.047 12.8 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase DUF2479 PF10651.4 CBK21890.2 - 0.13 11.8 0.2 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) Phospholip_B PF04916.8 CBK21891.2 - 2.8e-122 408.6 0.7 3.7e-122 408.2 0.5 1.0 1 0 0 1 1 1 1 Phospholipase B AAA PF00004.24 CBK21891.2 - 1.3e-34 119.2 0.0 2.2e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK21891.2 - 4.4e-06 26.7 4.1 9.5e-05 22.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBK21891.2 - 8e-06 26.0 0.1 0.00017 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBK21891.2 - 0.0014 18.3 0.1 0.031 14.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CBK21891.2 - 0.0016 17.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 CBK21891.2 - 0.0023 17.6 0.3 0.12 11.9 0.1 2.5 2 1 0 2 2 1 1 NACHT domain AAA_24 PF13479.1 CBK21891.2 - 0.0026 17.4 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK21891.2 - 0.0036 18.0 1.0 0.027 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK21891.2 - 0.0064 16.2 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CBK21891.2 - 0.01 15.8 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 CBK21891.2 - 0.011 14.8 0.0 0.058 12.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CBK21891.2 - 0.012 14.6 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CBK21891.2 - 0.028 14.1 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 CBK21891.2 - 0.057 12.8 0.0 0.56 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBK21891.2 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CBK21891.2 - 0.08 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 CBK21891.2 - 0.14 12.4 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBK21891.2 - 0.24 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_transf_49 PF13896.1 CBK21893.2 - 3.7e-18 65.6 0.2 1.1e-17 64.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Nsp1 PF11501.3 CBK21893.2 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 NOA36 PF06524.7 CBK21894.2 - 2.7e-85 286.4 44.6 3.3e-85 286.1 30.9 1.1 1 0 0 1 1 1 1 NOA36 protein zf-H2C2_2 PF13465.1 CBK21894.2 - 0.19 12.1 0.2 0.19 12.1 0.2 6.4 6 2 1 7 7 7 0 Zinc-finger double domain HA2 PF04408.18 CBK21895.2 - 3.5e-24 84.7 0.0 8.1e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK21895.2 - 4e-23 81.4 0.0 1.2e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK21895.2 - 4.8e-11 42.3 0.0 1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK21895.2 - 2.7e-07 30.2 0.2 5.7e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CBK21895.2 - 3.4e-05 23.5 0.0 0.00062 19.4 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 CBK21895.2 - 5.7e-05 23.2 0.1 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBK21895.2 - 0.0025 17.6 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBK21895.2 - 0.0037 16.2 0.1 0.01 14.7 0.0 1.7 1 1 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 CBK21895.2 - 0.023 14.1 0.0 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CBK21895.2 - 0.029 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBK21895.2 - 0.054 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK21895.2 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nup54 PF13874.1 CBK21896.2 - 0.00027 20.6 11.1 0.00027 20.6 7.7 3.9 2 2 1 3 3 3 2 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.2 CBK21896.2 - 0.00033 20.4 15.1 0.00033 20.4 10.5 3.9 3 2 1 4 4 4 1 Tropomyosin like CENP-F_leu_zip PF10473.4 CBK21896.2 - 0.0024 17.7 15.4 0.0024 17.7 10.7 4.6 2 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CBK21896.2 - 0.003 17.5 18.9 0.003 17.5 13.1 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF4200) Filament PF00038.16 CBK21896.2 - 0.0049 16.3 38.7 0.15 11.5 19.3 2.9 2 1 0 2 2 2 2 Intermediate filament protein DUF2746 PF10874.3 CBK21896.2 - 0.0068 16.5 8.4 0.13 12.5 1.1 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2746) CENP-H PF05837.7 CBK21896.2 - 0.009 16.1 3.6 0.009 16.1 2.5 4.3 3 1 1 4 4 3 1 Centromere protein H (CENP-H) DivIC PF04977.10 CBK21896.2 - 0.012 15.0 2.7 0.012 15.0 1.9 5.6 3 1 2 5 5 5 0 Septum formation initiator CALCOCO1 PF07888.6 CBK21896.2 - 0.17 10.1 32.3 0.0057 15.0 12.6 2.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 CBK21896.2 - 0.51 8.9 40.8 0.053 12.1 15.7 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Hemerythrin PF01814.18 CBK21896.2 - 1.2 9.2 7.8 0.51 10.4 2.6 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF972 PF06156.8 CBK21896.2 - 1.3 9.3 41.7 0.37 11.1 1.9 5.0 2 2 2 4 4 4 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 CBK21896.2 - 1.5 6.0 34.9 0.49 7.6 16.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Ax_dynein_light PF10211.4 CBK21896.2 - 1.6 8.5 37.9 0.057 13.2 3.2 4.2 2 1 1 3 3 3 0 Axonemal dynein light chain DUF2730 PF10805.3 CBK21896.2 - 2.5 7.8 18.8 0.44 10.3 0.5 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.7 CBK21896.2 - 2.6 8.0 13.4 0.03 14.2 2.6 2.8 3 0 0 3 3 3 0 MbeD/MobD like GAS PF13851.1 CBK21896.2 - 2.8 7.0 50.2 0.041 13.0 9.3 4.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 CBK21896.2 - 4.7 6.6 47.4 5.1 6.5 4.8 3.1 2 1 0 2 2 2 0 Ezrin/radixin/moesin family WEMBL PF05701.6 CBK21896.2 - 5.1 5.4 37.0 0.018 13.5 12.0 3.1 2 1 0 3 3 3 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 CBK21896.2 - 6.2 4.3 51.0 0.069 10.8 23.2 2.4 2 1 0 2 2 2 0 Myosin tail TMF_TATA_bd PF12325.3 CBK21896.2 - 6.7 6.4 42.2 2.2 8.0 7.2 4.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 CBK21896.2 - 7 7.0 55.2 1.3 9.3 9.8 5.9 3 1 1 4 4 4 0 Protein of unknown function (DUF904) Mnd1 PF03962.10 CBK21896.2 - 9.3 5.8 43.3 0.36 10.4 10.8 4.1 2 1 2 4 4 4 0 Mnd1 family potato_inhibit PF00280.13 CBK21898.2 - 1.6e-19 69.8 0.3 2.1e-19 69.4 0.2 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.3 CBK21898.2 - 0.083 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Ribosomal_L18e PF00828.14 CBK21900.2 - 2.9e-24 85.9 0.0 4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 OprF PF05736.6 CBK21900.2 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Sec7 PF01369.15 CBK21901.2 - 4e-23 82.0 0.7 7.9e-23 81.1 0.5 1.5 1 0 0 1 1 1 1 Sec7 domain Ribosomal_60s PF00428.14 CBK21902.2 - 6.8e-23 80.8 19.5 7.9e-23 80.6 13.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Myc_N PF01056.13 CBK21902.2 - 0.0099 15.0 1.4 0.012 14.7 1.0 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF867 PF05908.6 CBK21902.2 - 0.1 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) RR_TM4-6 PF06459.7 CBK21902.2 - 0.27 11.0 4.0 0.32 10.8 2.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.8 CBK21902.2 - 0.48 10.0 6.1 0.59 9.7 4.0 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region Shadoo PF14999.1 CBK21902.2 - 0.58 10.0 4.2 0.79 9.5 2.9 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Thioredoxin_6 PF13848.1 CBK21903.2 - 4.4e-08 33.1 0.0 6.8e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBK21903.2 - 0.0003 20.4 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PHD PF00628.24 CBK21904.2 - 1.7e-05 24.4 11.9 1.7e-05 24.4 8.2 3.2 3 1 0 3 3 3 1 PHD-finger GAGA PF09237.6 CBK21904.2 - 0.00013 21.4 0.5 0.00013 21.4 0.4 2.1 2 0 0 2 2 2 1 GAGA factor zf-Di19 PF05605.7 CBK21904.2 - 0.00019 21.4 2.5 0.00019 21.4 1.8 3.5 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBK21904.2 - 0.0011 19.1 1.4 0.1 12.8 0.3 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBK21904.2 - 0.014 15.5 1.1 7.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PHD_2 PF13831.1 CBK21904.2 - 0.077 12.3 7.7 0.021 14.1 2.7 2.1 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.8 CBK21904.2 - 0.11 12.2 8.8 0.13 11.9 0.4 3.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.9 CBK21904.2 - 0.43 10.0 2.6 1.6 8.2 0.3 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Fork_head_N PF08430.7 CBK21904.2 - 2.4 8.5 65.8 42 4.5 45.6 2.3 1 1 0 1 1 1 0 Forkhead N-terminal region FYVE_2 PF02318.11 CBK21904.2 - 7.6 6.4 12.0 0.37 10.6 3.8 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger Rhomboid PF01694.17 CBK21905.2 - 6.9e-14 52.0 7.4 1.9e-13 50.6 5.1 1.6 1 1 0 1 1 1 1 Rhomboid family DUF4079 PF13301.1 CBK21905.2 - 0.088 12.8 0.1 3.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Ist1 PF03398.9 CBK21907.2 - 7.2e-22 77.5 0.0 9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Peptidase_M24 PF00557.19 CBK21908.2 - 1.1e-38 132.8 0.0 1.5e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TPR_11 PF13414.1 CBK21910.2 - 1.8e-06 27.5 0.3 0.00013 21.5 0.0 3.3 4 0 0 4 4 4 1 TPR repeat Cohesin_load PF10345.4 CBK21910.2 - 0.0012 17.1 0.5 0.0024 16.1 0.3 1.5 1 0 0 1 1 1 1 Cohesin loading factor TPR_8 PF13181.1 CBK21910.2 - 0.0028 17.3 0.0 10 6.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK21910.2 - 0.0045 16.8 0.1 5.3 7.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK21910.2 - 0.0046 17.4 0.1 17 6.3 0.0 4.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK21910.2 - 0.063 12.9 0.2 9.9 5.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Phlebovirus_G1 PF07243.6 CBK21910.2 - 0.093 10.8 0.1 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 TPR_16 PF13432.1 CBK21910.2 - 0.12 13.0 0.0 60 4.4 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.1 CBK21911.2 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Herpes_TK_C PF08465.5 CBK21911.2 - 0.043 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal P21-Arc PF04062.9 CBK21912.2 - 9.1e-50 168.8 0.1 1.1e-49 168.5 0.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Cyclin_N PF00134.18 CBK21913.2 - 2.6e-14 52.8 0.6 3.6e-14 52.4 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBK21913.2 - 0.00061 19.7 2.0 0.00064 19.6 0.1 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain PCI PF01399.22 CBK21914.2 - 2.1e-13 50.4 0.9 1.5e-12 47.7 0.0 2.7 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 CBK21914.2 - 9.6e-06 25.4 0.2 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 zf-DHHC PF01529.15 CBK21915.2 - 6.3e-13 48.4 4.4 7.7e-13 48.2 3.0 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Acetyltransf_3 PF13302.1 CBK21916.2 - 3.7e-33 114.6 0.0 4.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK21916.2 - 1.3e-11 44.6 0.2 1.5e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK21916.2 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SMK-1 PF04802.10 CBK21917.2 - 3.7e-25 88.5 2.0 3.7e-25 88.5 1.4 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 FUR PF01475.14 CBK21917.2 - 0.082 12.8 0.1 0.28 11.1 0.1 1.9 1 1 0 1 1 1 0 Ferric uptake regulator family Aa_trans PF01490.13 CBK21918.2 - 1.2e-37 129.4 22.7 1.4e-37 129.2 15.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1218 PF06749.7 CBK21918.2 - 0.14 12.6 2.2 0.22 11.9 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Bromodomain PF00439.20 CBK21919.2 - 1.1e-17 63.6 0.0 2.2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain SH3_1 PF00018.23 CBK21919.2 - 0.00089 18.5 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBK21919.2 - 0.0055 16.2 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBK21919.2 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Acetyltransf_1 PF00583.19 CBK21920.2 - 1.9e-10 40.6 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBK21920.2 - 2.5e-05 24.3 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBK21920.2 - 0.00025 21.1 0.1 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK21920.2 - 0.0015 18.4 0.4 0.0015 18.4 0.3 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBK21920.2 - 0.034 13.9 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK21920.2 - 0.047 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.19 CBK21921.2 - 1.8e-18 66.3 0.1 3.5e-15 55.7 0.0 3.0 4 0 0 4 4 4 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBK21921.2 - 1.7e-10 41.0 0.0 7.1e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK21921.2 - 9.3e-09 34.9 0.0 8.7e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 CBK21921.2 - 1.2e-07 31.7 1.7 5.4e-07 29.6 0.1 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBK21921.2 - 7.4e-05 22.9 0.1 0.0039 17.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBK21921.2 - 8.9e-05 22.4 0.1 0.00075 19.4 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain NMT PF01233.14 CBK21921.2 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain RRM_1 PF00076.17 CBK21922.2 - 1.8e-06 27.4 0.0 5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK21922.2 - 1.2e-05 25.1 0.0 5.4e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 CBK21924.2 - 1.9e-98 329.2 0.8 2.2e-98 329.0 0.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Mak16 PF04874.9 CBK21924.2 - 0.059 13.4 0.4 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region SSF PF00474.12 CBK21925.2 - 3.5e-26 91.7 27.5 3.5e-26 91.7 19.0 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family UPF0093 PF03653.8 CBK21925.2 - 0.024 14.5 0.0 0.024 14.5 0.0 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0093) PNP_UDP_1 PF01048.15 CBK21926.2 - 2.7e-25 88.7 0.0 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily BAF1_ABF1 PF04684.8 CBK21927.2 - 9.4 4.9 14.2 17 4.1 9.8 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SGS PF05002.10 CBK21928.2 - 9.2e-17 60.5 2.2 1.6e-16 59.8 1.5 1.5 1 1 0 1 1 1 1 SGS domain CS PF04969.11 CBK21928.2 - 1.3e-12 48.1 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 CS domain XG_FTase PF03254.8 CBK21929.2 - 0.00031 19.3 0.0 0.00036 19.1 0.0 1.1 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase zf-RING_2 PF13639.1 CBK21931.2 - 2.3e-14 52.9 6.2 6.4e-14 51.5 4.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBK21931.2 - 9.2e-10 38.0 4.9 2.6e-09 36.6 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBK21931.2 - 7.7e-09 35.5 4.8 1.6e-08 34.5 2.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBK21931.2 - 6e-08 32.2 5.7 1.8e-07 30.7 3.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK21931.2 - 7.9e-08 32.2 6.3 2.3e-07 30.7 4.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK21931.2 - 2.4e-07 30.3 2.3 7.1e-07 28.8 1.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 CBK21931.2 - 3.9e-06 26.4 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-Apc11 PF12861.2 CBK21931.2 - 5.6e-06 26.1 0.9 1.9e-05 24.3 0.6 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CBK21931.2 - 0.0039 16.8 3.7 0.0083 15.7 2.6 1.6 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 CBK21931.2 - 0.0041 17.1 5.3 0.0089 16.0 3.7 1.6 1 0 0 1 1 1 1 RING-variant domain COX14 PF14880.1 CBK21931.2 - 0.015 14.9 0.5 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly zf-RING_4 PF14570.1 CBK21931.2 - 0.026 14.1 3.8 0.067 12.7 2.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CBK21931.2 - 0.046 13.2 3.3 0.16 11.5 2.3 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pribosyl_synth PF14572.1 CBK21931.2 - 0.062 13.0 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain FANCL_C PF11793.3 CBK21931.2 - 0.079 12.9 4.0 0.37 10.7 2.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 CBK21931.2 - 0.098 12.4 6.0 0.14 11.9 0.4 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 CBK21931.2 - 0.51 10.2 5.9 0.67 9.8 2.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 CBK21931.2 - 0.64 10.2 4.0 3.9 7.7 1.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Metallophos_2 PF12850.2 CBK21932.2 - 3.5e-10 39.9 0.0 4.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Hydrolase PF00702.21 CBK21933.2 - 1.4e-09 38.6 0.0 1.7e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK21933.2 - 2.4e-07 31.1 0.1 9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK21933.2 - 3.9e-06 26.7 0.0 1.7e-05 24.6 0.0 2.0 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK21933.2 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PUF PF00806.14 CBK21935.2 - 6.3e-40 132.4 5.0 3.1e-05 23.2 0.0 8.1 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF260 PF03195.9 CBK21935.2 - 0.052 13.8 1.6 0.28 11.4 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function DUF260 TFIIA PF03153.8 CBK21935.2 - 0.68 9.7 13.4 0.96 9.2 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.8 CBK21935.2 - 4 5.8 7.0 6.1 5.2 4.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF918 PF06033.6 CBK21936.2 - 0.0048 16.4 0.0 0.0055 16.2 0.0 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) MIF PF01187.13 CBK21936.2 - 0.0083 16.1 0.0 0.009 16.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF4054 PF13262.1 CBK21936.2 - 0.11 12.7 0.0 0.13 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Sdh_cyt PF01127.17 CBK21938.2 - 1.2e-12 47.6 4.4 1.7e-12 47.1 3.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PgaD PF13994.1 CBK21938.2 - 0.078 12.4 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein Glyco_hydro_32N PF00251.15 CBK21938.2 - 0.079 12.2 0.2 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Ribosomal_S10 PF00338.17 CBK21939.2 - 2.2e-30 104.3 1.3 2.6e-30 104.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e B12-binding PF02310.14 CBK21939.2 - 0.08 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Ribosomal_S19e PF01090.14 CBK21940.2 - 2.5e-34 117.6 0.0 2.7e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HrcA_DNA-bdg PF03444.10 CBK21940.2 - 0.049 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ribosomal_L40e PF01020.12 CBK21941.2 - 1e-31 108.2 13.7 1.7e-31 107.5 9.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBK21941.2 - 1.7e-17 62.5 0.0 2.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK21941.2 - 6.2e-11 41.8 0.3 8.9e-11 41.3 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK21941.2 - 0.025 14.7 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain FGGY_C PF02782.11 CBK21942.2 - 1.7e-58 197.5 1.5 2.4e-58 197.0 1.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBK21942.2 - 7.6e-56 189.1 0.0 1.1e-55 188.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RabGAP-TBC PF00566.13 CBK21943.2 - 1.5e-12 47.4 0.1 2.6e-11 43.4 0.1 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 CBK21944.2 - 4.3e-20 72.1 1.8 4.3e-20 72.1 1.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF2935 PF11155.3 CBK21944.2 - 0.075 13.1 2.9 0.13 12.3 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Syntaxin PF00804.20 CBK21944.2 - 9.3 6.4 11.9 1.6e+02 2.5 8.2 2.3 1 1 0 1 1 1 0 Syntaxin FKBP_C PF00254.23 CBK21945.2 - 8.6e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIS_C PF01096.13 CBK21946.2 - 4.7e-15 54.9 1.0 4.7e-15 54.9 0.7 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) MOSC PF03473.12 CBK21946.2 - 0.0039 16.6 0.2 0.0085 15.5 0.0 1.6 2 0 0 2 2 2 1 MOSC domain Rpr2 PF04032.11 CBK21946.2 - 0.085 12.7 7.8 0.13 12.1 0.3 2.4 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 CBK21946.2 - 0.099 12.4 0.4 0.099 12.4 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 CBK21946.2 - 0.16 11.6 7.5 0.079 12.7 0.8 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIIC PF12660.2 CBK21946.2 - 0.22 11.4 2.6 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Baculo_LEF5_C PF11792.3 CBK21946.2 - 0.59 9.5 0.0 0.59 9.5 0.0 3.0 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain GFA PF04828.9 CBK21946.2 - 0.66 9.9 5.4 6.6 6.7 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-FPG_IleRS PF06827.9 CBK21946.2 - 1 9.0 6.5 3.1 7.5 0.5 3.2 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF2387 PF09526.5 CBK21946.2 - 1.1 9.2 3.7 4.5 7.2 0.2 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Auto_anti-p27 PF06677.7 CBK21946.2 - 3.2 7.5 0.0 3.2 7.5 0.0 2.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.2 CBK21946.2 - 3.8 7.3 7.2 1.1 9.0 0.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 CBK21946.2 - 5.5 7.3 8.4 0.48 10.7 0.3 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Coatomer_WDAD PF04053.9 CBK21947.2 - 7.4e-86 288.6 0.0 2.2e-85 287.1 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 CBK21947.2 - 1.6e-59 201.5 0.3 2.4e-59 200.9 0.2 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CBK21947.2 - 4.4e-59 194.3 13.3 4.1e-10 39.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CBK21947.2 - 7.7e-05 21.0 5.7 0.065 11.3 0.1 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK21947.2 - 0.74 8.4 3.6 5.5 5.6 0.2 3.1 2 1 2 4 4 4 0 Nup133 N terminal like FSH1 PF03959.8 CBK21948.2 - 3.6e-51 173.6 0.0 4e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CBK21948.2 - 2.1e-07 30.6 0.0 5.8e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBK21948.2 - 4.8e-06 26.3 0.0 7.9e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBK21948.2 - 7.5e-05 22.7 0.0 0.079 12.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBK21948.2 - 0.0018 17.5 0.0 0.0056 15.9 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 CBK21948.2 - 0.014 15.1 0.3 0.063 12.9 0.0 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CBK21948.2 - 0.025 13.8 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DEAD PF00270.24 CBK21949.2 - 6e-42 143.0 0.4 9.8e-42 142.3 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21949.2 - 2.6e-22 78.4 0.0 5.8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBK21949.2 - 2.8e-09 36.3 0.0 6.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBK21949.2 - 1.3e-07 31.6 0.0 5.5e-07 29.5 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBK21949.2 - 1.6e-05 23.8 0.0 2.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2348 PF09807.4 CBK21949.2 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) AAA_22 PF13401.1 CBK21949.2 - 0.12 12.5 2.1 0.74 9.9 1.5 2.3 1 1 0 1 1 1 0 AAA domain Urocanase PF01175.13 CBK21950.2 - 6.8e-220 730.7 0.2 8.7e-220 730.3 0.1 1.0 1 0 0 1 1 1 1 Urocanase DUF1828 PF08861.5 CBK21951.2 - 0.019 14.6 1.4 0.28 10.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Alpha-2-MRAP_C PF06401.6 CBK21951.2 - 0.19 11.5 14.1 0.11 12.2 7.7 2.1 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain ALMT PF11744.3 CBK21951.2 - 0.3 9.6 6.1 0.43 9.1 4.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TBPIP PF07106.8 CBK21951.2 - 1.9 8.0 24.1 2.4 7.6 10.4 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF745 PF05335.8 CBK21951.2 - 7.3 6.0 10.7 1.9 7.9 4.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF745) EST1_DNA_bind PF10373.4 CBK21953.2 - 2.7e-28 98.9 1.3 4e-28 98.4 0.9 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CBK21953.2 - 3.5e-06 27.0 1.9 0.079 12.9 0.0 2.5 1 1 1 2 2 2 2 Telomerase activating protein Est1 TPR_11 PF13414.1 CBK21953.2 - 0.0037 16.8 0.2 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 CBK21953.2 - 0.024 14.7 0.2 0.23 11.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat NAP PF00956.13 CBK21954.2 - 1 8.4 2.4 3.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Ribosomal_S8e PF01201.17 CBK21958.2 - 3.3e-39 134.0 2.9 1.4e-38 132.0 2.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e UCH PF00443.24 CBK21959.2 - 2.1e-28 99.1 0.4 3e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBK21959.2 - 3.5e-17 62.2 11.2 3.5e-17 62.2 7.8 2.7 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBK21959.2 - 8.1e-11 41.8 2.7 1.5e-09 37.7 1.9 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBK21959.2 - 0.0007 18.9 1.4 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UPF1_Zn_bind PF09416.5 CBK21959.2 - 0.24 10.9 7.5 0.12 11.9 3.0 2.1 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) DUF3795 PF12675.2 CBK21959.2 - 4 7.6 14.4 5 7.3 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) UBA_4 PF14555.1 CBK21960.2 - 2.1e-07 30.3 0.0 4.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-UBP PF02148.14 CBK21960.2 - 0.0005 20.1 2.2 0.0005 20.1 1.5 2.3 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2180 PF09947.4 CBK21960.2 - 0.0083 15.8 1.1 0.026 14.2 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2180) Pkinase PF00069.20 CBK21961.2 - 2.2e-34 118.7 0.0 2.6e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21961.2 - 7.7e-12 44.8 0.0 9.6e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK21961.2 - 0.0018 18.0 0.0 0.14 11.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family TBPIP PF07106.8 CBK21962.2 - 4.6e-43 146.6 7.2 5.7e-43 146.3 5.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 CBK21962.2 - 1.1e-05 25.2 6.9 1.3e-05 24.9 4.8 1.2 1 0 0 1 1 1 1 Mnd1 family Reo_sigmaC PF04582.7 CBK21962.2 - 0.00042 19.6 0.2 0.00056 19.1 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DivIC PF04977.10 CBK21962.2 - 0.00063 19.1 7.4 0.084 12.3 2.8 3.0 1 1 1 2 2 2 2 Septum formation initiator Penicillinase_R PF03965.11 CBK21962.2 - 0.0022 18.0 2.1 0.085 12.9 0.2 3.0 1 1 3 4 4 4 1 Penicillinase repressor WEMBL PF05701.6 CBK21962.2 - 0.0031 16.0 10.5 0.0039 15.7 7.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light V_ATPase_I PF01496.14 CBK21962.2 - 0.013 13.3 5.6 0.015 13.1 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.4 CBK21962.2 - 0.019 15.0 6.4 0.02 15.0 3.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 CBK21962.2 - 0.023 14.3 12.6 0.028 14.0 8.0 1.7 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 CBK21962.2 - 0.023 15.0 9.9 0.59 10.4 2.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 CBK21962.2 - 0.026 14.4 8.6 0.51 10.2 1.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 CBK21962.2 - 0.027 14.4 3.9 0.039 13.8 1.9 1.9 1 1 0 1 1 1 0 FlxA-like protein DUF1192 PF06698.6 CBK21962.2 - 0.033 14.0 13.6 0.14 11.9 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 CBK21962.2 - 0.042 13.6 7.5 0.079 12.8 5.2 1.5 1 0 0 1 1 1 0 Tropomyosin like AAA_27 PF13514.1 CBK21962.2 - 0.056 11.1 9.4 0.25 8.9 6.4 1.8 1 1 1 2 2 2 0 AAA domain SCO1-SenC PF02630.9 CBK21962.2 - 0.056 13.0 0.6 0.27 10.8 0.3 1.9 1 1 1 2 2 2 0 SCO1/SenC CENP-F_leu_zip PF10473.4 CBK21962.2 - 0.056 13.2 9.9 0.13 12.1 6.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PilJ PF13675.1 CBK21962.2 - 0.057 13.7 3.6 0.081 13.2 0.4 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 CBK21962.2 - 0.059 13.1 0.4 0.19 11.5 0.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 CBK21962.2 - 0.06 13.3 3.3 0.69 9.9 1.2 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Pro_dh PF01619.13 CBK21962.2 - 0.07 12.0 2.3 0.09 11.7 1.6 1.3 1 0 0 1 1 1 0 Proline dehydrogenase ATG16 PF08614.6 CBK21962.2 - 0.071 12.9 8.8 0.54 10.0 1.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 CBK21962.2 - 0.073 13.0 9.5 0.13 12.2 2.6 2.9 2 1 1 3 3 3 0 bZIP transcription factor NUC194 PF08163.7 CBK21962.2 - 0.078 11.8 4.3 0.098 11.4 3.0 1.1 1 0 0 1 1 1 0 NUC194 domain AAA_13 PF13166.1 CBK21962.2 - 0.09 11.2 6.2 0.12 10.7 4.3 1.3 1 0 0 1 1 1 0 AAA domain Chorismate_synt PF01264.16 CBK21962.2 - 0.099 11.1 0.4 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 Chorismate synthase Cep57_CLD_2 PF14197.1 CBK21962.2 - 0.12 12.3 6.6 1.2 9.1 4.6 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 FUSC PF04632.7 CBK21962.2 - 0.14 10.5 1.3 0.18 10.2 0.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seadorna_VP6 PF07407.6 CBK21962.2 - 0.15 10.8 1.2 0.19 10.4 0.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein TMF_DNA_bd PF12329.3 CBK21962.2 - 0.18 11.6 13.7 0.47 10.2 7.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3166 PF11365.3 CBK21962.2 - 0.2 12.1 7.3 0.67 10.4 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Fib_alpha PF08702.5 CBK21962.2 - 0.26 11.3 6.0 0.76 9.8 0.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 CBK21962.2 - 0.31 11.4 6.5 1.7 9.0 1.7 2.9 1 1 2 3 3 3 0 SlyX APG6 PF04111.7 CBK21962.2 - 0.32 9.9 12.4 0.099 11.6 6.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CBK21962.2 - 0.35 10.6 13.3 0.74 9.5 5.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.15 CBK21962.2 - 0.36 10.6 10.5 5.5 6.8 3.5 2.9 1 1 1 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.1 CBK21962.2 - 0.36 11.1 7.3 0.34 11.2 3.1 2.2 2 1 1 3 3 2 0 Snapin/Pallidin FtsK_SpoIIIE PF01580.13 CBK21962.2 - 0.43 10.0 4.9 0.23 10.9 1.4 1.8 1 1 0 2 2 2 0 FtsK/SpoIIIE family Med9 PF07544.8 CBK21962.2 - 0.43 10.3 7.2 0.17 11.6 1.8 2.4 2 2 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Spc24 PF08286.6 CBK21962.2 - 0.48 10.1 8.3 1.2 8.8 4.3 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 CBK21962.2 - 0.59 9.0 6.0 0.98 8.2 4.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CBK21962.2 - 0.73 8.1 9.8 0.41 9.0 3.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) FliJ PF02050.11 CBK21962.2 - 0.79 9.7 9.5 0.45 10.5 2.9 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein PspB PF06667.7 CBK21962.2 - 0.84 9.6 3.3 2.4 8.1 0.4 2.5 1 1 1 2 2 2 0 Phage shock protein B Ax_dynein_light PF10211.4 CBK21962.2 - 0.89 9.3 13.8 0.25 11.1 4.5 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain HALZ PF02183.13 CBK21962.2 - 1 9.0 7.7 0.86 9.3 1.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper CCDC155 PF14662.1 CBK21962.2 - 1.2 8.7 12.5 4.9 6.7 8.7 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Metal_resist PF13801.1 CBK21962.2 - 1.3 8.9 4.7 0.64 10.0 1.5 1.8 1 1 1 2 2 2 0 Heavy-metal resistance TPR_MLP1_2 PF07926.7 CBK21962.2 - 1.4 8.7 9.7 6 6.6 6.7 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 CBK21962.2 - 1.5 9.3 7.0 1.5 9.3 0.9 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.14 CBK21962.2 - 1.6 8.2 11.5 0.47 9.9 0.5 2.6 1 1 2 3 3 3 0 GrpE AAA_23 PF13476.1 CBK21962.2 - 1.6 9.0 10.5 2.1 8.6 7.3 1.2 1 0 0 1 1 1 0 AAA domain SYF2 PF08231.7 CBK21962.2 - 1.6 8.8 7.5 3 7.9 0.4 2.6 1 1 1 2 2 2 0 SYF2 splicing factor Seryl_tRNA_N PF02403.17 CBK21962.2 - 1.9 8.5 10.3 1.8 8.6 5.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.10 CBK21962.2 - 1.9 8.6 10.9 5.2 7.2 1.4 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus BRE1 PF08647.6 CBK21962.2 - 2.7 8.0 10.2 11 6.0 3.4 2.9 1 1 2 3 3 2 0 BRE1 E3 ubiquitin ligase DUF1843 PF08898.5 CBK21962.2 - 2.7 8.0 12.8 4.8 7.2 0.8 4.0 2 1 2 4 4 3 0 Domain of unknown function (DUF1843) FlaC_arch PF05377.6 CBK21962.2 - 3.6 7.5 11.2 0.55 10.1 1.6 3.4 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 CBK21962.2 - 5 7.4 10.0 9.5 6.5 6.4 1.9 1 1 0 1 1 1 0 Striatin family TBCA PF02970.11 CBK21962.2 - 6.3 6.9 10.8 5.9 7.0 4.3 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A bZIP_2 PF07716.10 CBK21962.2 - 6.4 6.6 11.7 5.2 6.9 1.4 2.8 3 0 0 3 3 2 0 Basic region leucine zipper zf-CCCH PF00642.19 CBK21963.2 - 2.1e-05 24.1 23.9 2.6e-05 23.7 3.5 2.8 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CBK21963.2 - 5 6.6 8.1 14 5.2 0.1 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain GD_AH_C PF04295.8 CBK21964.2 - 4e-94 315.5 0.0 5.1e-87 292.1 0.0 2.8 2 1 0 2 2 2 2 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.7 CBK21964.2 - 0.032 14.6 0.0 0.087 13.2 0.0 1.8 1 1 0 1 1 1 0 SAF domain Glyco_transf_22 PF03901.12 CBK21965.2 - 1.4e-28 100.0 22.5 1.7e-28 99.7 15.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Longin PF13774.1 CBK21966.2 - 8.5e-15 54.0 0.4 1.6e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBK21966.2 - 1.3e-14 53.5 0.4 5.2e-14 51.6 0.1 1.9 2 0 0 2 2 2 1 Synaptobrevin LOH1CR12 PF10158.4 CBK21966.2 - 0.084 12.6 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressor protein IncA PF04156.9 CBK21966.2 - 0.19 11.2 1.2 0.3 10.6 0.2 1.6 2 0 0 2 2 2 0 IncA protein Sec20 PF03908.8 CBK21966.2 - 9.3 6.0 7.3 2.8 7.7 1.3 2.7 2 2 0 2 2 2 0 Sec20 Sedlin_N PF04628.8 CBK21967.2 - 0.0014 18.4 0.2 0.0023 17.8 0.2 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region G10 PF01125.12 CBK21968.2 - 4.8e-49 165.6 9.0 5.4e-49 165.4 6.2 1.0 1 0 0 1 1 1 1 G10 protein IRF-2BP1_2 PF11261.3 CBK21968.2 - 0.066 12.6 2.4 0.11 11.9 1.7 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger DUF2387 PF09526.5 CBK21968.2 - 0.2 11.6 0.4 0.2 11.6 0.3 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Tmpp129 PF10272.4 CBK21968.2 - 4.7 5.8 10.7 5.5 5.6 7.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor SPASM PF13186.1 CBK21970.2 - 0.074 13.3 0.3 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Bac_rhamnosid_N PF08531.5 CBK21970.2 - 0.08 12.4 0.4 3.8 7.0 0.0 2.9 3 0 0 3 3 3 0 Alpha-L-rhamnosidase N-terminal domain LamB PF02264.10 CBK21971.2 - 0.0085 15.2 0.7 0.0093 15.0 0.5 1.1 1 0 0 1 1 1 1 LamB porin Peptidase_U57 PF05582.7 CBK21971.2 - 0.24 10.3 2.5 1.3 7.9 0.0 2.0 1 1 1 2 2 2 0 YabG peptidase U57 rRNA_proc-arch PF13234.1 CBK21972.2 - 1.1e-64 218.2 0.0 1.6e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CBK21972.2 - 1e-56 191.0 1.0 6e-56 188.5 0.3 2.4 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CBK21972.2 - 2.6e-12 46.5 0.0 1e-11 44.6 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK21972.2 - 9.1e-09 35.0 0.0 3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_1 PF00170.16 CBK21972.2 - 0.0081 16.1 0.4 0.027 14.4 0.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor DUF3450 PF11932.3 CBK21972.2 - 0.023 13.9 0.2 0.048 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 CBK21972.2 - 0.08 12.4 3.6 0.078 12.4 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.20 CBK21973.2 - 3.2e-67 226.4 0.0 3.7e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK21973.2 - 3.4e-36 124.6 0.0 4.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK21973.2 - 0.0015 17.5 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UDPGP PF01704.13 CBK21974.2 - 4.9e-12 45.0 0.0 6.1e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CBK21974.2 - 0.04 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain UDPGP PF01704.13 CBK21975.2 - 4.8e-24 84.6 0.0 7.1e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DnaJ PF00226.26 CBK21976.2 - 1.2e-21 76.2 1.2 2.3e-21 75.2 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBK21976.2 - 1.5e-16 60.0 0.0 9.5e-15 54.2 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBK21976.2 - 5.6e-15 55.1 14.2 1e-14 54.2 9.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Mitofilin PF09731.4 CBK21976.2 - 0.017 13.7 22.1 0.026 13.2 15.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ycf1 PF05758.7 CBK21976.2 - 0.025 12.3 7.4 0.033 11.9 5.1 1.2 1 0 0 1 1 1 0 Ycf1 DUF3482 PF11981.3 CBK21976.2 - 0.056 12.6 1.2 0.1 11.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) MIP-T3 PF10243.4 CBK21976.2 - 0.057 11.8 42.7 0.094 11.1 29.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HypA PF01155.14 CBK21976.2 - 0.07 12.8 10.3 0.25 11.0 0.9 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DDHD PF02862.12 CBK21976.2 - 0.085 12.6 9.0 0.19 11.5 6.2 1.6 1 0 0 1 1 1 0 DDHD domain ATP-synt_B PF00430.13 CBK21976.2 - 1 9.1 20.6 2 8.2 14.3 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) zf-RING_3 PF14369.1 CBK21976.2 - 1.1 9.3 8.6 3.4 7.7 1.4 3.3 3 1 1 4 4 4 0 zinc-finger DZR PF12773.2 CBK21976.2 - 4.3 7.2 12.2 75 3.2 8.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon CDC27 PF09507.5 CBK21976.2 - 7.4 5.6 34.9 13 4.8 24.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.15 CBK21976.2 - 9.5 3.9 16.5 13 3.5 11.4 1.2 1 0 0 1 1 1 0 Hsp70 protein GAGA_bind PF06217.7 CBK21976.2 - 9.8 6.0 16.3 20 5.0 11.3 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Pkinase PF00069.20 CBK21977.2 - 0.064 12.4 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain tRNA-synt_2c PF01411.14 CBK21978.2 - 4.9e-133 444.3 0.0 6.5e-133 443.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBK21978.2 - 2.4e-07 30.5 0.3 5.1e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Spike_rec_bind PF09408.5 CBK21979.2 - 0.0014 18.1 0.4 0.0023 17.4 0.3 1.3 1 0 0 1 1 1 1 Spike receptor binding domain LRR_8 PF13855.1 CBK21979.2 - 0.0052 16.5 0.5 4.7 7.0 0.0 2.8 2 1 0 2 2 2 2 Leucine rich repeat Sec5 PF15469.1 CBK21981.2 - 0.00087 19.0 1.2 0.0017 18.0 0.2 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 DUF2760 PF10816.3 CBK21981.2 - 0.043 13.3 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) Sec5 PF15469.1 CBK21982.2 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 CBK21982.2 - 0.0065 16.2 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 tRNA-synt_2c PF01411.14 CBK21983.2 - 7.1e-210 697.9 0.0 2.1e-209 696.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBK21983.2 - 2.4e-12 46.5 0.0 5.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CBK21983.2 - 8.8e-07 28.5 0.1 2.8e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain HSP20 PF00011.16 CBK21984.2 - 3.1e-27 94.3 2.9 3.7e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3716 PF12511.3 CBK21984.2 - 0.063 12.9 1.0 0.47 10.1 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF104 PF01954.11 CBK21984.2 - 0.089 12.8 1.8 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK21984.2 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Cpn60_TCP1 PF00118.19 CBK21985.2 - 5e-156 520.0 0.3 5.7e-156 519.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cullin PF00888.17 CBK21986.2 - 6.1e-45 153.8 10.2 9.6e-45 153.1 7.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBK21986.2 - 4.3e-07 29.6 0.3 1.5e-06 27.9 0.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_24 PF13412.1 CBK21986.2 - 0.037 13.4 1.9 0.079 12.3 0.0 2.7 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 CBK21986.2 - 0.045 13.4 1.5 0.3 10.7 0.0 3.1 3 0 0 3 3 3 0 HTH domain Porin_3 PF01459.17 CBK21987.2 - 6e-17 61.8 0.1 7.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin CcoS PF03597.10 CBK21987.2 - 0.34 10.4 1.5 0.6 9.6 1.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DER1 PF04511.10 CBK21988.2 - 5.1e-29 101.1 9.5 6e-29 100.9 6.6 1.0 1 0 0 1 1 1 1 Der1-like family UCH PF00443.24 CBK21989.2 - 3.7e-48 163.9 15.7 8.7e-22 77.4 21.7 2.9 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21989.2 - 1.2e-09 38.0 16.8 8.2e-08 32.0 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MIP-T3 PF10243.4 CBK21989.2 - 3.3 6.0 62.7 7.7 4.8 43.5 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF543 PF04418.7 CBK21990.2 - 8.6e-08 32.0 0.1 9.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF340 PF03956.8 CBK21990.2 - 0.091 12.0 0.5 0.11 11.7 0.4 1.1 1 0 0 1 1 1 0 Membrane protein of unknown function (DUF340) MtrF PF09472.5 CBK21990.2 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PHD PF00628.24 CBK21991.2 - 2.3e-06 27.1 17.6 2.3e-06 27.1 12.2 2.6 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CBK21991.2 - 0.00011 21.3 12.9 0.00011 21.3 9.0 2.0 2 0 0 2 2 2 1 PHD-finger NAD_binding_6 PF08030.7 CBK21992.2 - 5.1e-13 49.2 0.0 8.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CBK21992.2 - 0.0083 16.2 2.0 0.018 15.1 1.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component UCH PF00443.24 CBK21993.2 - 3.2e-08 33.0 0.1 4.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21993.2 - 0.0046 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.9 CBK21993.2 - 0.034 13.7 0.2 0.079 12.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS UCH PF00443.24 CBK21994.2 - 6.4e-36 123.8 0.0 7.1e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK21994.2 - 1.5e-08 34.4 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2514 PF10721.4 CBK21995.2 - 0.18 11.5 1.2 0.28 10.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) WD40 PF00400.27 CBK21996.2 - 4.9e-19 67.4 20.9 4.8e-06 26.2 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat RRM_5 PF13893.1 CBK21996.2 - 0.032 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop PF01798.13 CBK21997.2 - 7.4e-37 125.9 0.4 1.4e-36 125.0 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CBK21997.2 - 9.7e-20 71.2 1.6 9.7e-20 71.2 1.1 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 CBK21997.2 - 6.9e-13 48.1 0.4 2.3e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain DUF3184 PF11380.3 CBK21998.2 - 2.2e-08 32.5 0.1 2.4e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3184) AAA_18 PF13238.1 CBK21999.2 - 1.4e-14 54.4 0.3 3.1e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Porin_3 PF01459.17 CBK22000.2 - 9.1e-16 57.9 0.1 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Rep_fac-A_3 PF08661.6 CBK22001.2 - 2.1e-15 56.5 0.0 2.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 RNase_T PF00929.19 CBK22002.2 - 6.7e-25 88.2 0.0 9.3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBK22002.2 - 0.00056 19.4 0.0 0.0019 17.6 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Cpn60_TCP1 PF00118.19 CBK22003.2 - 5e-156 520.0 0.3 5.7e-156 519.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP20 PF00011.16 CBK22004.2 - 3.1e-27 94.3 2.9 3.7e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3716 PF12511.3 CBK22004.2 - 0.063 12.9 1.0 0.47 10.1 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF104 PF01954.11 CBK22004.2 - 0.089 12.8 1.8 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK22004.2 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Pkinase PF00069.20 CBK22006.2 - 2.8e-45 154.5 0.0 3.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22006.2 - 2.5e-24 85.7 0.0 3.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK22006.2 - 2.1e-06 27.6 0.0 0.00096 18.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK22006.2 - 2.9e-05 23.1 0.0 0.0031 16.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 CBK22006.2 - 0.0053 15.6 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 V-SNARE_C PF12352.3 CBK22007.2 - 1.4e-05 25.0 3.2 4.3e-05 23.5 2.0 1.8 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBK22007.2 - 2.4e-05 23.9 0.8 3.3e-05 23.4 0.6 1.3 1 0 0 1 1 1 1 Sec20 DUF912 PF06024.7 CBK22007.2 - 0.0037 17.2 0.2 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0118 PF01594.11 CBK22007.2 - 0.0043 16.0 0.7 0.0044 16.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 Prominin PF05478.6 CBK22007.2 - 0.039 11.4 0.4 0.047 11.2 0.3 1.0 1 0 0 1 1 1 0 Prominin OppC_N PF12911.2 CBK22007.2 - 0.12 11.8 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Synaptobrevin PF00957.16 CBK22007.2 - 0.14 11.7 4.6 0.29 10.7 3.2 1.6 1 1 0 1 1 1 0 Synaptobrevin TarH PF02203.10 CBK22007.2 - 3.5 7.4 5.7 18 5.1 0.1 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue WD40 PF00400.27 CBK22008.2 - 1.3e-21 75.5 1.2 2.6e-06 27.0 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBK22008.2 - 0.00031 19.1 0.0 0.015 13.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 CBK22008.2 - 0.0021 16.7 0.0 0.28 9.7 0.0 2.3 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) DUF2694 PF10904.3 CBK22008.2 - 0.0099 15.8 0.3 0.018 14.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2694) SGL PF08450.7 CBK22008.2 - 0.01 15.2 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Cpn10 PF00166.16 CBK22010.2 - 1e-24 86.2 0.0 1.2e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF128 PF01995.11 CBK22010.2 - 0.061 12.2 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF128 Peptidase_U4 PF03419.8 CBK22010.2 - 0.1 11.6 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TPR_12 PF13424.1 CBK22011.2 - 1.1e-19 70.1 0.6 5.6e-07 29.4 0.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBK22011.2 - 5.3e-11 42.0 1.1 0.00017 21.1 0.6 4.4 3 1 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 CBK22011.2 - 4.8e-10 38.4 0.6 0.0076 15.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK22011.2 - 1.3e-08 34.7 0.1 0.54 11.0 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK22011.2 - 2.9e-08 33.0 6.7 0.17 11.8 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK22011.2 - 1.3e-06 28.6 0.3 0.0047 17.2 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_6 PF13516.1 CBK22011.2 - 1.4e-06 27.7 1.0 0.048 13.7 0.3 4.0 3 0 0 3 3 3 2 Leucine Rich repeat TPR_6 PF13174.1 CBK22011.2 - 1.5e-06 28.2 2.9 0.63 10.6 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK22011.2 - 1.9e-05 24.0 6.6 2 8.3 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBK22011.2 - 0.0003 20.5 0.1 0.19 11.6 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK22011.2 - 0.00036 20.0 8.4 0.019 14.5 0.0 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat LRR_4 PF12799.2 CBK22011.2 - 0.00039 19.9 0.3 0.0014 18.1 0.2 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) TPR_16 PF13432.1 CBK22011.2 - 0.00052 20.6 3.5 0.025 15.2 0.2 4.5 5 2 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK22011.2 - 0.00065 19.7 1.0 0.9 9.7 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBK22011.2 - 0.0065 16.5 0.0 15 6.0 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat LRR_1 PF00560.28 CBK22011.2 - 0.01 15.7 0.6 0.68 10.1 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CBK22011.2 - 0.026 14.6 2.7 0.36 11.2 0.1 4.1 3 0 0 3 3 2 0 Leucine rich repeat PKD_channel PF08016.7 CBK22011.2 - 0.037 12.4 0.1 0.1 10.9 0.0 1.7 2 0 0 2 2 2 0 Polycystin cation channel E1-E2_ATPase PF00122.15 CBK22014.2 - 1.1e-52 178.4 0.1 1.1e-52 178.4 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK22014.2 - 4.7e-36 124.0 10.1 4.7e-36 124.0 7.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK22014.2 - 8.6e-23 81.8 0.0 8.7e-17 62.2 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK22014.2 - 3.1e-14 52.6 0.0 9.6e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBK22014.2 - 1.6e-10 41.4 0.0 7e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK22014.2 - 0.005 16.4 0.2 0.12 11.9 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KRTAP PF11759.3 CBK22015.2 - 0.053 13.7 11.1 0.093 12.9 7.7 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Gly-zipper_Omp PF13488.1 CBK22015.2 - 0.18 11.4 48.2 1.5e+04 -12.0 33.4 2.7 1 1 0 1 1 1 0 Glycine zipper tRNA_m1G_MT PF01746.16 CBK22016.2 - 3.8e-28 98.3 0.2 3.8e-28 98.3 0.1 1.9 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Plectin PF00681.15 CBK22016.2 - 0.099 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Plectin repeat Di19_C PF14571.1 CBK22016.2 - 2 8.7 7.0 3.9 7.8 4.9 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Ribosomal_L37 PF08561.5 CBK22017.2 - 1.7e-12 46.7 1.8 2.6e-12 46.1 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 LRR_6 PF13516.1 CBK22018.2 - 4.8e-18 63.1 22.1 0.0047 16.8 0.2 12.6 14 0 0 14 14 14 5 Leucine Rich repeat LRR_4 PF12799.2 CBK22018.2 - 6e-12 44.9 18.5 0.00025 20.6 0.7 9.1 8 1 1 9 9 9 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBK22018.2 - 1.2e-06 27.6 27.2 0.22 11.6 0.1 10.6 11 1 1 12 12 12 2 Leucine Rich Repeat LRR_8 PF13855.1 CBK22018.2 - 0.0005 19.7 26.1 0.41 10.4 2.0 8.8 9 3 1 10 10 10 3 Leucine rich repeat LRR_7 PF13504.1 CBK22018.2 - 0.0011 18.8 21.8 6.1 7.5 0.0 9.5 11 0 0 11 11 11 2 Leucine rich repeat DUF2893 PF11459.3 CBK22018.2 - 0.14 12.0 0.8 25 4.7 0.1 3.4 4 0 0 4 4 4 0 Protein of unknwon function (DUF2893) HAD PF12710.2 CBK22019.2 - 1.6e-16 61.0 0.0 2.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CBK22019.2 - 0.0006 19.2 0.0 0.0008 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 CBK22019.2 - 0.004 17.3 0.0 0.0062 16.7 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBK22019.2 - 0.0099 16.3 0.0 0.036 14.4 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Rdx PF10262.4 CBK22020.2 - 6.7e-07 29.2 0.0 9.6e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Rdx family ABC2_membrane_2 PF12679.2 CBK22020.2 - 0.048 12.5 0.6 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Nsp1_C PF05064.8 CBK22021.2 - 3.1e-13 49.4 9.8 1.1e-10 41.2 3.8 2.2 1 1 1 2 2 2 2 Nsp1-like C-terminal region NPV_P10 PF05531.7 CBK22021.2 - 9.8e-05 22.5 3.9 0.0022 18.2 0.1 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 CBK22021.2 - 0.00018 21.3 1.9 0.082 12.7 0.0 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 CBK22021.2 - 0.00028 20.2 2.9 0.27 10.6 0.0 3.3 3 1 0 3 3 3 1 Chordopoxvirus fusion protein Fez1 PF06818.10 CBK22021.2 - 0.0004 20.4 6.3 0.00046 20.2 4.3 1.1 1 0 0 1 1 1 1 Fez1 Snapin_Pallidin PF14712.1 CBK22021.2 - 0.00046 20.4 9.9 0.0026 18.0 3.0 3.0 2 1 1 3 3 3 1 Snapin/Pallidin DUF1664 PF07889.7 CBK22021.2 - 0.00072 19.3 10.6 0.0036 17.1 5.3 2.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) DUF677 PF05055.7 CBK22021.2 - 0.00072 18.3 2.0 0.00092 17.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) APG6 PF04111.7 CBK22021.2 - 0.00087 18.4 5.3 0.0012 18.0 3.6 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-K PF11802.3 CBK22021.2 - 0.001 18.3 4.3 0.0011 18.2 3.0 1.2 1 0 0 1 1 1 1 Centromere-associated protein K DUF3584 PF12128.3 CBK22021.2 - 0.0012 16.3 7.9 0.0016 15.8 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) V-SNARE PF05008.10 CBK22021.2 - 0.0018 18.3 7.7 0.0094 16.0 4.1 2.7 2 1 1 3 3 2 1 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.8 CBK22021.2 - 0.0033 18.1 8.8 0.22 12.2 2.8 3.0 1 1 2 3 3 3 1 Occludin homology domain PspA_IM30 PF04012.7 CBK22021.2 - 0.0045 16.3 5.2 0.39 10.0 1.3 3.4 2 1 1 3 3 3 1 PspA/IM30 family Laminin_II PF06009.7 CBK22021.2 - 0.0045 16.7 7.0 0.046 13.4 2.0 2.7 1 1 2 3 3 3 2 Laminin Domain II AAA_13 PF13166.1 CBK22021.2 - 0.005 15.3 7.9 0.0067 14.9 5.5 1.3 1 1 0 1 1 1 1 AAA domain WXG100 PF06013.7 CBK22021.2 - 0.0052 16.7 3.3 0.068 13.1 0.5 3.2 1 1 2 3 3 2 2 Proteins of 100 residues with WXG DUF3375 PF11855.3 CBK22021.2 - 0.0054 15.5 2.1 0.012 14.3 1.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3375) PTRF_SDPR PF15237.1 CBK22021.2 - 0.0056 16.1 5.5 0.0098 15.3 3.8 1.3 1 0 0 1 1 1 1 PTRF/SDPR family Spectrin PF00435.16 CBK22021.2 - 0.0061 16.8 7.8 0.038 14.2 4.5 2.4 1 1 1 2 2 2 1 Spectrin repeat Sipho_Gp157 PF05565.6 CBK22021.2 - 0.0084 15.7 3.4 0.36 10.4 0.4 3.0 1 1 1 2 2 2 1 Siphovirus Gp157 Reo_sigmaC PF04582.7 CBK22021.2 - 0.009 15.2 4.8 0.023 13.9 2.9 1.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein TMPIT PF07851.8 CBK22021.2 - 0.012 14.7 5.2 0.019 14.0 3.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF1515 PF07439.6 CBK22021.2 - 0.014 15.1 2.3 0.22 11.3 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) Prefoldin_2 PF01920.15 CBK22021.2 - 0.016 14.9 10.2 0.89 9.3 0.2 3.1 3 1 0 3 3 3 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CBK22021.2 - 0.016 14.8 8.8 0.028 14.1 3.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KCNQ_channel PF03520.9 CBK22021.2 - 0.019 14.3 5.1 0.021 14.1 2.5 1.8 1 1 1 2 2 2 0 KCNQ voltage-gated potassium channel DUF4200 PF13863.1 CBK22021.2 - 0.02 14.8 6.8 0.1 12.5 4.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 CBK22021.2 - 0.023 14.8 10.0 0.8 9.8 0.9 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HeLo PF14479.1 CBK22021.2 - 0.032 13.9 3.9 0.042 13.5 2.7 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation EzrA PF06160.7 CBK22021.2 - 0.04 12.1 9.6 1.2 7.2 2.9 2.5 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF3452 PF11934.3 CBK22021.2 - 0.045 13.0 1.3 0.33 10.2 0.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) IFT57 PF10498.4 CBK22021.2 - 0.045 12.4 7.4 0.058 12.1 5.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4164 PF13747.1 CBK22021.2 - 0.054 13.6 4.8 0.076 13.1 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Dynamitin PF04912.9 CBK22021.2 - 0.056 12.2 9.3 0.097 11.4 5.0 1.9 1 1 0 2 2 2 0 Dynamitin FH2 PF02181.18 CBK22021.2 - 0.058 12.2 4.3 0.83 8.4 3.1 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain Prefoldin PF02996.12 CBK22021.2 - 0.066 12.8 6.0 1.9 8.1 0.7 3.0 3 1 1 4 4 2 0 Prefoldin subunit HSP70 PF00012.15 CBK22021.2 - 0.077 10.9 3.7 0.091 10.6 2.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Tropomyosin PF00261.15 CBK22021.2 - 0.093 11.8 6.3 0.24 10.4 4.4 1.7 1 1 0 1 1 1 0 Tropomyosin DUF3391 PF11871.3 CBK22021.2 - 0.099 12.8 2.3 0.14 12.3 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2408 PF10303.4 CBK22021.2 - 0.1 12.7 7.0 0.074 13.1 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) MCPsignal PF00015.16 CBK22021.2 - 0.1 12.1 4.7 1.4 8.3 0.5 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.6 CBK22021.2 - 0.1 12.4 6.0 4.2 7.3 0.8 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AATF-Che1 PF13339.1 CBK22021.2 - 0.11 12.6 7.2 0.21 11.7 5.0 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor IncA PF04156.9 CBK22021.2 - 0.11 12.0 12.7 0.081 12.5 7.0 1.7 1 1 0 2 2 2 0 IncA protein Selenoprotein_S PF06936.6 CBK22021.2 - 0.13 11.8 1.8 0.19 11.2 1.2 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) TACC PF05010.9 CBK22021.2 - 0.2 11.4 10.2 0.17 11.6 1.3 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) DUF964 PF06133.6 CBK22021.2 - 0.23 11.5 6.6 1.2 9.1 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Tropomyosin_1 PF12718.2 CBK22021.2 - 0.23 11.3 8.5 0.26 11.1 5.0 1.8 1 1 1 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 CBK22021.2 - 0.25 11.2 9.2 1.3 8.8 4.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4570 PF15134.1 CBK22021.2 - 0.26 11.1 5.3 1.1 9.1 1.4 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4570) DUF342 PF03961.8 CBK22021.2 - 0.26 9.6 5.3 0.42 8.9 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBK22021.2 - 0.27 11.6 7.6 1.3 9.3 3.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EMP24_GP25L PF01105.19 CBK22021.2 - 0.3 10.7 8.9 0.31 10.7 0.9 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 CBK22021.2 - 0.31 11.1 12.7 0.47 10.5 7.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 CBK22021.2 - 0.32 10.9 13.8 0.44 10.5 1.7 2.4 1 1 1 2 2 2 0 FlxA-like protein ORF6C PF10552.4 CBK22021.2 - 0.34 10.6 5.0 2.7 7.7 0.0 3.1 2 2 1 3 3 3 0 ORF6C domain DUF724 PF05266.9 CBK22021.2 - 0.34 10.5 7.1 0.6 9.6 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.11 CBK22021.2 - 0.36 11.0 9.1 0.68 10.1 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.14 CBK22021.2 - 0.37 8.5 3.5 0.42 8.3 2.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CBK22021.2 - 0.37 11.2 9.3 1.4 9.3 1.8 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Spc24 PF08286.6 CBK22021.2 - 0.39 10.4 8.1 4.1 7.1 0.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Allexi_40kDa PF05549.6 CBK22021.2 - 0.46 9.7 9.0 3.4 6.8 0.2 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2203 PF09969.4 CBK22021.2 - 0.51 10.5 4.7 2.4 8.3 2.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) EAP30 PF04157.11 CBK22021.2 - 0.53 9.4 6.5 0.46 9.6 3.1 1.9 1 1 0 2 2 2 0 EAP30/Vps36 family FliJ PF02050.11 CBK22021.2 - 0.53 10.3 9.3 0.7 9.9 3.3 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein GCN5L1 PF06320.8 CBK22021.2 - 0.66 9.8 5.9 1.7 8.4 1.6 2.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) PspB PF06667.7 CBK22021.2 - 0.71 9.8 5.3 14 5.7 0.0 3.3 2 1 2 4 4 4 0 Phage shock protein B Jnk-SapK_ap_N PF09744.4 CBK22021.2 - 0.73 9.8 8.0 4.2 7.3 0.1 2.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF3734 PF12536.3 CBK22021.2 - 0.76 9.9 5.9 2.2 8.4 2.5 2.1 1 1 1 2 2 2 0 Patatin phospholipase DivIC PF04977.10 CBK22021.2 - 0.83 9.1 6.1 0.8 9.2 0.1 2.8 2 1 1 3 3 2 0 Septum formation initiator Cortex-I_coil PF09304.5 CBK22021.2 - 0.94 9.5 9.0 1.6 8.8 2.7 2.8 1 1 2 3 3 3 0 Cortexillin I, coiled coil IFP_35_N PF07334.8 CBK22021.2 - 1.1 9.3 5.2 0.88 9.5 0.4 2.8 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Med9 PF07544.8 CBK22021.2 - 1.1 8.9 9.1 3.5 7.4 2.2 3.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YlqD PF11068.3 CBK22021.2 - 1.3 9.0 8.5 0.88 9.6 3.4 2.2 1 1 2 3 3 3 0 YlqD protein Prominin PF05478.6 CBK22021.2 - 1.4 6.3 7.2 2.3 5.6 5.0 1.4 1 1 0 1 1 1 0 Prominin CorA PF01544.13 CBK22021.2 - 2.2 7.2 7.5 4.2 6.3 3.5 1.9 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Syntaxin_2 PF14523.1 CBK22021.2 - 2.2 8.3 10.6 14 5.7 7.0 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Syntaxin PF00804.20 CBK22021.2 - 2.7 8.2 11.9 4.2 7.5 5.9 2.6 1 1 1 2 2 2 0 Syntaxin DUF3713 PF12506.3 CBK22021.2 - 2.7 8.0 6.9 34 4.5 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF948 PF06103.6 CBK22021.2 - 4.1 7.3 6.7 3.6 7.5 2.2 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 CBK22021.2 - 6.7 6.3 8.6 12 5.5 4.5 2.3 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF2951 PF11166.3 CBK22021.2 - 6.7 6.6 8.3 14 5.6 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) SHIPPO-rpt PF07004.7 CBK22022.2 - 1.2e-06 29.1 79.2 10 7.2 0.3 19.1 4 3 9 13 13 13 5 Sperm-tail PG-rich repeat Nucleoporin_FG PF13634.1 CBK22022.2 - 0.89 9.7 128.6 1.5e+04 -83.6 89.2 5.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region GIY-YIG PF01541.19 CBK22023.2 - 7.3e-12 45.4 0.2 1.2e-11 44.7 0.2 1.5 1 1 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 CBK22023.2 - 0.00021 21.6 0.5 0.00027 21.2 0.4 1.3 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 CBK22023.2 - 0.025 15.0 0.2 0.038 14.4 0.2 1.4 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Ribosomal_L37e PF01907.14 CBK22023.2 - 0.037 13.8 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e EF-hand_1 PF00036.27 CBK22024.2 - 2.8e-25 85.6 4.2 2.4e-07 29.5 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CBK22024.2 - 2.2e-23 80.0 3.0 4.4e-07 29.2 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CBK22024.2 - 1.3e-20 73.2 1.5 3.2e-11 43.1 0.1 3.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 CBK22024.2 - 2.5e-20 71.8 6.1 2.2e-08 33.5 0.0 4.9 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 CBK22024.2 - 8e-17 59.7 7.0 6.9e-05 21.9 0.3 5.1 5 0 0 5 5 5 4 EF hand EF-hand_10 PF14788.1 CBK22024.2 - 0.0035 16.9 0.6 1 9.0 0.0 3.3 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 CBK22024.2 - 0.0036 17.3 0.1 1.4 8.9 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBK22024.2 - 0.018 14.7 1.5 5 6.9 0.1 3.6 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand C2 PF00168.25 CBK22025.2 - 8.5e-09 35.1 0.1 1.3e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain DAO PF01266.19 CBK22026.2 - 1.2e-32 113.1 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Herpes_UL51 PF04540.8 CBK22026.2 - 0.13 11.7 0.0 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus UL51 protein 2TM PF13239.1 CBK22028.2 - 0.0013 18.7 0.5 0.0015 18.5 0.3 1.1 1 0 0 1 1 1 1 2TM domain CbiQ PF02361.11 CBK22028.2 - 0.096 12.2 0.3 0.1 12.1 0.2 1.0 1 0 0 1 1 1 0 Cobalt transport protein Pkinase PF00069.20 CBK22029.2 - 2.7e-52 177.4 0.2 1.1e-50 172.2 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22029.2 - 3.3e-28 98.4 0.0 1.7e-23 83.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBK22029.2 - 0.0013 17.7 0.0 0.0024 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK22029.2 - 0.046 13.4 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CBK22029.2 - 0.15 11.0 0.1 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.15 CBK22030.2 - 1.7e-17 62.9 0.1 3.5e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBK22030.2 - 0.00011 21.9 0.1 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CBK22030.2 - 0.00036 20.6 1.0 0.002 18.2 0.1 2.6 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK22030.2 - 0.00073 19.7 1.1 0.0015 18.7 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK22030.2 - 0.0027 17.7 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 CBK22030.2 - 0.016 14.7 0.2 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Redoxin Thioredoxin_9 PF14595.1 CBK22030.2 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 CBK22030.2 - 0.81 9.1 0.0 0.81 9.1 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein CDC27 PF09507.5 CBK22030.2 - 2.2 7.3 17.0 3.1 6.8 11.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mito_carr PF00153.22 CBK22031.2 - 1e-05 25.1 0.1 1.2e-05 24.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Dynein_IC2 PF11540.3 CBK22031.2 - 0.061 12.6 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 AP3B1_C PF14796.1 CBK22031.2 - 0.11 12.1 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal DUF3675 PF12428.3 CBK22032.2 - 0.061 13.5 0.1 0.061 13.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF4407 PF14362.1 CBK22032.2 - 0.13 11.2 16.4 0.18 10.7 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1777 PF08648.7 CBK22032.2 - 2.3 7.9 29.1 3.5 7.3 20.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CDC27 PF09507.5 CBK22032.2 - 2.6 7.1 45.4 3.3 6.8 31.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MMR1 PF08505.5 CBK22032.2 - 7.5 6.5 20.6 9.8 6.1 14.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2146 PF10220.4 CBK22032.2 - 8.6 4.1 17.0 9.5 4.0 11.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MIP-T3 PF10243.4 CBK22032.2 - 8.7 4.6 48.3 11 4.3 33.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_C1 PF00112.18 CBK22033.2 - 1.4e-86 289.9 21.4 3.9e-46 157.6 5.2 2.0 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBK22033.2 - 0.00025 19.6 7.1 0.004 15.7 0.6 2.2 2 0 0 2 2 2 2 Peptidase C1-like family SNF2_N PF00176.18 CBK22034.2 - 1.1e-64 218.1 0.1 1.7e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK22034.2 - 6.3e-18 64.4 0.0 6.6e-17 61.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK22034.2 - 3.1e-07 30.4 0.0 9.1e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK22034.2 - 3.7e-05 23.2 0.0 0.00032 20.2 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBK22034.2 - 0.00061 18.6 0.3 0.002 16.9 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Viral_helicase1 PF01443.13 CBK22034.2 - 0.021 14.3 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CAF1 PF04857.15 CBK22035.2 - 2e-52 178.1 0.0 3.6e-52 177.3 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease SpoU_methylase PF00588.14 CBK22036.2 - 3.7e-28 98.1 0.2 4.8e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF2423 PF10338.4 CBK22039.2 - 0.022 14.7 0.3 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) S4 PF01479.20 CBK22041.2 - 6.8e-13 47.8 0.1 1.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.17 CBK22041.2 - 3.8e-11 43.0 0.0 1.6e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase RRM_2 PF04059.7 CBK22042.2 - 3.6e-08 33.2 0.0 4.2e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 CBK22042.2 - 1.1e-06 28.1 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK22042.2 - 7.7e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22042.2 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3023 PF11224.3 CBK22042.2 - 0.018 14.7 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) zf-RING_4 PF14570.1 CBK22042.2 - 0.053 13.1 0.2 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain BRAP2 PF07576.7 CBK22042.2 - 0.053 13.0 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Bromodomain PF00439.20 CBK22043.2 - 3.8e-17 61.9 0.0 5.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain MoeA_C PF03454.10 CBK22043.2 - 0.079 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) UCH PF00443.24 CBK22044.2 - 9.2e-10 38.0 0.2 1e-09 37.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FGGY_N PF00370.16 CBK22045.2 - 7.6e-56 189.1 0.0 9.5e-25 87.3 0.0 4.5 2 2 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBK22045.2 - 2.1e-33 115.6 0.0 2.3e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain MOR2-PAG1_mid PF14228.1 CBK22045.2 - 0.031 11.8 0.0 3.2 5.1 0.0 2.1 2 0 0 2 2 2 0 Cell morphogenesis central region Transpos_assoc PF13963.1 CBK22045.2 - 0.093 12.7 0.8 21 5.1 0.1 2.6 2 0 0 2 2 2 0 Transposase-associated domain HECT PF00632.20 CBK22046.2 - 3.2e-60 203.9 0.0 4.2e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) adh_short_C2 PF13561.1 CBK22047.2 - 4e-68 229.7 0.1 4.5e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBK22047.2 - 5.2e-10 39.4 0.0 6.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.3 CBK22047.2 - 0.036 13.0 0.0 0.089 11.7 0.0 1.6 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region OmpH PF03938.9 CBK22048.2 - 0.015 15.2 5.2 0.015 15.2 3.6 3.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.1 CBK22048.2 - 0.027 13.6 45.7 0.13 11.4 2.4 4.3 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2580 PF10824.3 CBK22048.2 - 2.2 8.6 7.7 3.2 8.1 0.2 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2580) CENP-F_leu_zip PF10473.4 CBK22048.2 - 5.2 6.9 55.2 0.44 10.3 13.2 5.0 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2877 PF11392.3 CBK22048.2 - 5.9 7.1 7.4 1.9 8.7 0.1 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2877) DUF1664 PF07889.7 CBK22048.2 - 8.2 6.2 17.1 2.8 7.7 2.8 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Ras PF00071.17 CBK22050.2 - 2.8e-57 192.6 0.1 4.7e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK22050.2 - 6.1e-21 75.1 0.0 1.2e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK22050.2 - 3.4e-13 49.2 0.1 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK22050.2 - 2.5e-07 30.0 0.1 3.4e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBK22050.2 - 1.2e-06 27.8 0.0 2.7e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBK22050.2 - 4.7e-05 22.8 0.1 0.00041 19.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK22050.2 - 0.0008 19.3 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBK22050.2 - 0.0037 17.2 0.3 0.57 10.1 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 CBK22050.2 - 0.014 15.0 0.0 0.033 13.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CBK22050.2 - 0.023 14.9 0.0 0.047 13.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CBK22050.2 - 0.043 13.9 0.0 0.33 11.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF2491 PF10679.4 CBK22050.2 - 0.063 12.2 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF2075 PF09848.4 CBK22050.2 - 0.065 12.2 0.0 0.24 10.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 CBK22050.2 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain BT1 PF03092.11 CBK22051.2 - 4.3e-15 55.3 9.6 5.1e-15 55.1 6.7 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBK22051.2 - 0.029 13.0 15.7 0.032 12.9 10.9 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Dpy19 PF10034.4 CBK22051.2 - 7.7 4.5 11.0 8 4.4 7.6 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation MORN PF02493.15 CBK22052.2 - 5.3e-06 25.8 14.6 0.42 10.4 1.7 4.9 5 0 0 5 5 5 4 MORN repeat DUF563 PF04577.9 CBK22053.2 - 1.1e-18 67.9 0.2 2.6e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) zf-DHHC PF01529.15 CBK22054.2 - 1.1e-24 86.7 13.9 1.1e-24 86.7 9.7 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 CBK22054.2 - 0.023 14.8 6.8 0.047 13.8 4.7 1.5 1 0 0 1 1 1 0 Plexin repeat DUF2207 PF09972.4 CBK22054.2 - 0.043 12.4 1.0 0.056 12.0 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4239 PF14023.1 CBK22054.2 - 0.046 13.0 2.5 0.048 13.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Ank_2 PF12796.2 CBK22055.2 - 1.6e-34 118.1 7.3 1.8e-20 73.0 0.8 3.0 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBK22055.2 - 2.9e-26 89.9 3.0 7.7e-08 31.7 0.1 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CBK22055.2 - 1.4e-21 76.4 1.2 6.2e-08 32.9 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBK22055.2 - 4.5e-21 74.3 3.6 4.5e-12 45.7 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK22055.2 - 1e-17 62.4 1.5 0.00039 20.3 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat NOG1 PF06858.9 CBK22056.2 - 5.3e-23 80.6 0.2 1.3e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CBK22056.2 - 4.9e-15 55.4 0.0 1.1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.6 CBK22056.2 - 1.1e-13 50.6 0.6 1.1e-13 50.6 0.4 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.13 CBK22056.2 - 1.9e-07 30.4 0.0 3.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBK22056.2 - 0.0069 16.8 0.0 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 CBK22056.2 - 0.011 14.8 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF258 PF03193.11 CBK22056.2 - 0.017 14.3 0.0 0.14 11.3 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBK22056.2 - 0.098 12.4 0.9 15 5.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family VWA_2 PF13519.1 CBK22057.2 - 1.9e-05 24.8 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_transf_49 PF13896.1 CBK22058.2 - 5.2e-07 29.0 0.7 5.9e-07 28.8 0.5 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Arm PF00514.18 CBK22059.2 - 3e-08 33.1 50.9 0.087 12.6 0.0 23.1 27 0 0 27 27 27 5 Armadillo/beta-catenin-like repeat ADP_ribosyl_GH PF03747.9 CBK22059.2 - 4.1 7.1 0.0 18 5.0 0.0 2.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase tRNA_U5-meth_tr PF05958.6 CBK22060.2 - 5.7e-21 74.5 0.0 1.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CBK22060.2 - 5.8e-14 51.9 0.6 1e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBK22060.2 - 4.5e-08 32.6 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBK22060.2 - 6.4e-08 32.6 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22060.2 - 9.6e-08 32.5 0.0 2.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH PF00642.19 CBK22060.2 - 4.3e-06 26.2 1.1 1.2e-05 24.8 0.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_25 PF13649.1 CBK22060.2 - 1.1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBK22060.2 - 1.7e-05 23.9 0.0 1.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 CBK22060.2 - 4.5e-05 22.6 0.0 8.4e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CBK22060.2 - 0.00023 21.5 0.0 0.00085 19.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK22060.2 - 0.00097 19.5 0.1 0.0042 17.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 CBK22060.2 - 0.0023 17.5 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 CBK22060.2 - 0.0027 16.8 0.0 0.0027 16.8 0.0 2.1 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 CBK22060.2 - 0.0034 16.9 3.4 0.0097 15.4 0.0 3.0 4 0 0 4 4 4 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 CBK22060.2 - 0.006 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CBK22060.2 - 0.072 12.4 0.0 0.072 12.4 0.0 2.2 2 0 0 2 2 1 0 Conserved hypothetical protein 95 Ndc1_Nup PF09531.5 CBK22060.2 - 0.08 11.3 1.2 0.16 10.3 0.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.7 CBK22060.2 - 0.48 8.1 10.1 0.74 7.4 7.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBK22060.2 - 0.54 10.0 10.5 1.1 9.0 7.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mitofilin PF09731.4 CBK22060.2 - 0.63 8.6 18.1 0.87 8.1 12.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ECH PF00378.15 CBK22061.2 - 4.2e-20 71.9 0.0 4.9e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family LRR_4 PF12799.2 CBK22062.2 - 2.4e-17 62.1 6.1 0.0055 16.2 0.2 5.7 5 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBK22062.2 - 3.9e-12 44.9 24.9 0.37 11.0 0.2 9.3 10 1 1 11 11 11 6 Leucine Rich repeat LRR_8 PF13855.1 CBK22062.2 - 5.3e-10 38.9 15.7 0.015 15.0 0.2 5.4 3 1 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBK22062.2 - 1.6e-07 30.3 27.9 4.3 7.7 0.0 9.2 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 CBK22062.2 - 6e-05 22.6 22.9 9.7 6.8 0.0 9.5 9 1 1 10 10 10 1 Leucine rich repeat Pkinase PF00069.20 CBK22063.2 - 1.6e-44 152.0 0.0 2.3e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22063.2 - 1.6e-41 142.0 0.0 2.1e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK22063.2 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1939 PF09154.5 CBK22063.2 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) UEV PF05743.8 CBK22063.2 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 UEV domain He_PIG PF05345.7 CBK22064.2 - 2.8e-39 132.8 53.7 3e-08 33.5 1.1 7.7 6 0 0 6 6 6 6 Putative Ig domain F5_F8_type_C PF00754.20 CBK22064.2 - 6.6e-08 32.4 14.0 1.6e-05 24.7 0.5 4.1 4 0 0 4 4 4 2 F5/8 type C domain RCR PF12273.3 CBK22064.2 - 0.0016 18.9 0.8 0.004 17.7 0.0 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF843 PF05814.6 CBK22064.2 - 0.18 11.5 0.9 0.39 10.5 0.6 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF2036 PF09724.4 CBK22065.2 - 0.016 14.3 4.6 0.02 14.0 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Peptidase_S10 PF00450.17 CBK22065.2 - 0.63 9.1 12.6 0.69 9.0 8.7 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase ACCA PF03255.9 CBK22065.2 - 0.83 9.1 8.7 1.7 8.1 6.0 1.6 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4045 PF13254.1 CBK22065.2 - 1.2 8.3 13.5 1.5 8.0 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Fork_head_N PF08430.7 CBK22065.2 - 8.2 6.8 70.4 8e+02 0.3 48.8 2.1 1 1 0 1 1 1 0 Forkhead N-terminal region DUF4206 PF13901.1 CBK22065.2 - 8.3 5.9 13.1 9.9 5.6 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) SNF2_N PF00176.18 CBK22066.2 - 1.2e-68 231.0 1.7 1.7e-68 230.6 1.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK22066.2 - 4.9e-16 58.3 0.1 2.1e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22066.2 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.19 CBK22066.2 - 2e-06 27.3 2.3 2.4e-05 23.9 1.6 2.6 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 CBK22066.2 - 1.1e-05 25.3 0.0 0.00011 22.0 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBK22066.2 - 0.028 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3 PF00933.16 CBK22068.2 - 1.8e-62 211.0 0.0 2.5e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CBK22068.2 - 9.7e-35 120.1 0.0 1.4e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CBK22068.2 - 1.1e-11 44.4 0.1 2.6e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_M16_C PF05193.16 CBK22069.2 - 1.7e-27 96.2 0.0 3.6e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBK22069.2 - 1.2e-19 70.5 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PseudoU_synth_2 PF00849.17 CBK22070.2 - 2.2e-22 79.6 0.0 3.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Hydrolase_6 PF13344.1 CBK22071.2 - 1.1e-31 108.6 0.0 1.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBK22071.2 - 6.4e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBK22071.2 - 1.4e-08 35.3 0.0 4.6e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK22071.2 - 3e-06 27.5 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CBK22071.2 - 0.00042 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.9 CBK22071.2 - 0.00052 19.4 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M22 PF00814.20 CBK22072.2 - 1.1e-84 284.1 0.0 1.4e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family NPFF PF15085.1 CBK22075.2 - 0.011 15.9 0.6 0.022 15.0 0.4 1.5 1 0 0 1 1 1 0 Neuropeptide FF He_PIG PF05345.7 CBK22076.2 - 4e-16 58.7 41.3 1.5e-05 24.9 4.6 5.5 4 1 0 4 4 4 3 Putative Ig domain I-set PF07679.11 CBK22076.2 - 0.00022 21.0 2.5 3.2 7.6 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain TMEM154 PF15102.1 CBK22076.2 - 0.0026 17.4 2.4 0.0026 17.4 1.7 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF912 PF06024.7 CBK22076.2 - 0.0047 16.9 1.0 0.0098 15.9 0.7 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 CBK22076.2 - 0.022 15.1 1.0 0.045 14.1 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 CBK22076.2 - 0.034 13.5 0.5 0.061 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rifin_STEVOR PF02009.11 CBK22076.2 - 0.046 13.3 4.4 0.11 12.1 3.1 1.5 1 0 0 1 1 1 0 Rifin/stevor family F5_F8_type_C PF00754.20 CBK22076.2 - 0.047 13.5 18.1 0.08 12.7 0.1 4.7 5 1 0 5 5 4 0 F5/8 type C domain Baculo_11_kDa PF06143.6 CBK22076.2 - 0.055 12.8 3.2 0.11 11.8 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.1 CBK22076.2 - 0.071 13.2 2.5 0.16 12.1 1.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.4 CBK22076.2 - 0.14 11.6 2.1 0.4 10.1 1.4 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1180 PF06679.7 CBK22076.2 - 0.22 11.4 2.8 0.2 11.5 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) OAD_gamma PF04277.8 CBK22076.2 - 0.29 11.5 4.4 0.79 10.1 3.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain P12 PF12669.2 CBK22076.2 - 0.46 10.7 3.8 0.88 9.8 2.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family ASFV_J13L PF05568.6 CBK22076.2 - 6.6 6.2 9.8 1.9 7.9 3.9 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein HCO3_cotransp PF00955.16 CBK22077.2 - 6e-20 71.3 0.6 8.3e-20 70.9 0.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family SAM_2 PF07647.12 CBK22077.2 - 0.00057 19.6 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HCO3_cotransp PF00955.16 CBK22078.2 - 1.3e-27 96.6 0.2 1.3e-27 96.6 0.1 2.3 3 0 0 3 3 3 2 HCO3- transporter family WD40 PF00400.27 CBK22079.2 - 5.1e-30 102.2 12.9 1.9e-10 40.2 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat tRNA-synt_1f PF01921.13 CBK22079.2 - 0.17 10.5 2.2 0.36 9.4 1.5 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) TFIIIC_delta PF12657.2 CBK22079.2 - 0.89 9.2 11.5 2.6 7.7 0.0 3.7 2 2 2 4 4 4 0 Transcription factor IIIC subunit delta N-term He_PIG PF05345.7 CBK22080.2 - 4.1e-16 58.7 43.9 1.5e-05 24.9 4.6 5.4 4 1 0 4 4 4 3 Putative Ig domain I-set PF07679.11 CBK22080.2 - 0.00016 21.4 2.7 2.1 8.2 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain TMEM154 PF15102.1 CBK22080.2 - 0.0027 17.4 2.5 0.0027 17.4 1.7 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF912 PF06024.7 CBK22080.2 - 0.0055 16.7 0.9 0.011 15.7 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) F5_F8_type_C PF00754.20 CBK22080.2 - 0.0067 16.2 18.2 0.065 13.0 0.6 4.9 5 1 0 5 5 4 2 F5/8 type C domain EphA2_TM PF14575.1 CBK22080.2 - 0.022 15.1 1.0 0.045 14.1 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CBK22080.2 - 0.023 14.3 3.6 0.055 13.1 2.5 1.5 1 0 0 1 1 1 0 Rifin/stevor family DUF1510 PF07423.6 CBK22080.2 - 0.034 13.5 0.5 0.061 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Baculo_11_kDa PF06143.6 CBK22080.2 - 0.055 12.8 3.2 0.11 11.8 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.1 CBK22080.2 - 0.088 12.9 2.7 0.19 11.8 1.9 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.4 CBK22080.2 - 0.088 12.2 1.7 0.25 10.7 1.2 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1180 PF06679.7 CBK22080.2 - 0.091 12.6 3.0 0.072 12.9 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) OAD_gamma PF04277.8 CBK22080.2 - 0.29 11.5 4.4 0.79 10.1 3.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain P12 PF12669.2 CBK22080.2 - 0.46 10.7 3.8 0.88 9.8 2.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family ASFV_J13L PF05568.6 CBK22080.2 - 6.5 6.2 9.8 1.9 7.9 3.9 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein NPFF PF15085.1 CBK22081.2 - 0.013 15.7 0.5 0.029 14.6 0.3 1.6 1 0 0 1 1 1 0 Neuropeptide FF Zip PF02535.17 CBK22082.2 - 1.8e-17 63.3 6.1 2.3e-17 62.9 4.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Pyr_redox_2 PF07992.9 CBK22083.2 - 2.9e-28 99.1 0.0 4.5e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBK22083.2 - 1e-27 96.3 0.0 1.5e-26 92.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBK22083.2 - 3e-17 62.7 0.0 8.8e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK22083.2 - 4.5e-11 43.1 0.0 6.1e-10 39.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBK22083.2 - 2.5e-07 29.5 0.5 5.6e-05 21.7 0.1 2.4 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 CBK22083.2 - 3.5e-05 22.8 2.8 0.00018 20.4 1.9 2.0 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 CBK22083.2 - 3.6e-05 22.8 0.0 0.00022 20.2 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 CBK22083.2 - 6.2e-05 22.2 0.6 0.0001 21.5 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CBK22083.2 - 6.3e-05 22.0 0.8 0.00022 20.2 0.6 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 CBK22083.2 - 0.00083 18.3 1.5 0.0032 16.4 0.3 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBK22083.2 - 0.0016 17.6 0.1 0.0028 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CBK22083.2 - 0.0029 17.5 0.8 0.017 15.1 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CBK22083.2 - 0.061 12.2 0.1 0.18 10.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DFP PF04127.10 CBK22084.2 - 1.3e-15 57.4 0.0 3.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein COMPASS-Shg1 PF05205.7 CBK22084.2 - 0.082 13.2 0.0 0.73 10.1 0.0 2.3 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 RRM_1 PF00076.17 CBK22085.2 - 5.1e-19 67.6 0.0 8.8e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK22085.2 - 1e-11 44.5 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22085.2 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3752 PF12572.3 CBK22086.2 - 4.8e-05 23.5 2.4 4.8e-05 23.5 1.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3752) Seryl_tRNA_N PF02403.17 CBK22086.2 - 0.069 13.1 0.4 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain VIT1 PF01988.14 CBK22086.2 - 0.28 10.6 0.7 0.44 9.9 0.5 1.3 1 0 0 1 1 1 0 VIT family Atrophin-1 PF03154.10 CBK22086.2 - 0.44 8.6 2.5 0.5 8.4 1.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Snf7 PF03357.16 CBK22087.2 - 1.7e-14 53.5 7.4 2e-14 53.3 5.2 1.0 1 0 0 1 1 1 1 Snf7 DUF725 PF05267.7 CBK22087.2 - 2.1 8.2 10.1 0.34 10.8 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF725) PAP2 PF01569.16 CBK22088.2 - 1.9e-19 69.6 1.9 2.7e-19 69.1 1.3 1.3 1 0 0 1 1 1 1 PAP2 superfamily RseC_MucC PF04246.7 CBK22088.2 - 5 6.6 5.4 0.94 9.0 0.6 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC E1_DerP2_DerF2 PF02221.10 CBK22089.2 - 3.3e-11 43.5 0.0 4.1e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 ML domain Peptidase_M24 PF00557.19 CBK22090.2 - 3.8e-38 131.1 0.0 5.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CBK22090.2 - 7e-28 97.7 0.0 4.6e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pkinase PF00069.20 CBK22091.2 - 7.3e-56 189.1 0.0 1.6e-55 188.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22091.2 - 7.1e-26 90.8 0.0 9.3e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22091.2 - 1.9e-06 27.0 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK22091.2 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MT-A70 PF05063.9 CBK22092.2 - 0.00044 19.8 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 MT-A70 AMP-binding PF00501.23 CBK22093.2 - 8.9e-68 228.5 0.0 2.5e-67 227.0 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBK22093.2 - 0.00077 20.3 0.4 0.0019 19.1 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 CBK22094.2 - 5.3e-27 94.3 1.4 1.6e-26 92.7 1.0 1.7 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4131 PF13567.1 CBK22095.2 - 0.064 12.6 0.1 0.074 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NADH-u_ox-rdase PF10785.4 CBK22095.2 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SET PF00856.23 CBK22096.2 - 6.8e-07 29.7 0.1 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 SET domain TruB_N PF01509.13 CBK22097.2 - 0.0006 20.0 0.0 0.0019 18.3 0.0 1.9 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Rdx PF10262.4 CBK22098.2 - 2e-07 30.9 1.7 3.2e-07 30.2 1.2 1.4 1 1 0 1 1 1 1 Rdx family PHD PF00628.24 CBK22099.2 - 9.1e-14 50.8 38.8 0.00012 21.7 7.6 3.3 2 1 1 3 3 3 3 PHD-finger zf-RING-like PF08746.6 CBK22099.2 - 0.0015 18.5 4.6 0.0015 18.5 3.2 3.5 3 1 0 3 3 3 2 RING-like domain zf-PHD-like PF15446.1 CBK22099.2 - 0.096 11.9 25.4 0.13 11.5 3.2 3.3 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-C4_ClpX PF06689.8 CBK22099.2 - 0.12 11.8 0.5 0.12 11.8 0.4 4.3 3 2 1 4 4 4 0 ClpX C4-type zinc finger Histone PF00125.19 CBK22100.2 - 3.2e-22 78.4 0.1 3.9e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK22100.2 - 0.002 18.1 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Spc97_Spc98 PF04130.8 CBK22103.2 - 4.1e-23 81.5 0.5 5.7e-23 81.0 0.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Sdh5 PF03937.11 CBK22104.2 - 1.3e-21 76.0 0.3 2.3e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Na_H_antiporter PF03553.9 CBK22105.2 - 1.1e-47 162.5 16.0 1.1e-47 162.5 11.1 2.7 1 1 0 2 2 2 1 Na+/H+ antiporter family DUF1517 PF07466.6 CBK22105.2 - 0.14 11.0 0.1 0.14 11.0 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1517) ASF1_hist_chap PF04729.8 CBK22106.2 - 8e-51 171.7 0.3 1.3e-50 171.0 0.2 1.3 1 1 0 1 1 1 1 ASF1 like histone chaperone Pkinase PF00069.20 CBK22107.2 - 5.1e-62 209.3 0.0 6.9e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22107.2 - 1.9e-28 99.2 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK22107.2 - 0.00032 19.8 0.0 0.00063 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.24 CBK22107.2 - 0.016 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_8 PF15409.1 CBK22107.2 - 0.037 14.0 0.1 0.094 12.7 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.1 CBK22107.2 - 0.041 14.1 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.18 CBK22107.2 - 0.056 13.1 0.3 1 9.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_C13 PF01650.13 CBK22108.2 - 1.6e-80 270.1 0.0 2.5e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.13 CBK22109.2 - 1.2e-76 257.4 0.0 1.9e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family DUF1764 PF08576.5 CBK22111.2 - 4.5e-14 53.0 0.9 4.7e-14 52.9 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) zf-Tim10_DDP PF02953.10 CBK22112.2 - 1.6e-13 49.6 2.2 1.9e-13 49.5 1.5 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Neur_chan_memb PF02932.11 CBK22113.2 - 0.011 15.6 0.4 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RsbRD_N PF14361.1 CBK22113.2 - 0.082 13.3 0.5 0.17 12.3 0.4 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain SieB PF14163.1 CBK22113.2 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B FLO_LFY PF01698.11 CBK22113.2 - 0.13 11.0 7.5 0.18 10.6 5.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2413 PF10310.4 CBK22113.2 - 0.37 9.5 13.7 0.53 9.0 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4228 PF14009.1 CBK22113.2 - 0.52 10.4 6.1 0.94 9.5 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Senescence_reg PF04520.8 CBK22113.2 - 1.7 9.1 8.2 2.7 8.4 5.7 1.3 1 0 0 1 1 1 0 Senescence regulator Vfa1 PF08432.5 CBK22113.2 - 1.9 8.5 18.5 3 7.8 12.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF740 PF05340.7 CBK22113.2 - 6.8 4.9 10.7 8.7 4.5 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Daxx PF03344.10 CBK22113.2 - 8.6 4.7 20.7 11 4.3 14.4 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 CBK22113.2 - 8.7 6.2 20.0 14 5.5 13.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Bax1-I PF01027.15 CBK22114.2 - 9.6e-21 74.3 14.8 1.2e-20 74.0 10.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CbiN PF02553.10 CBK22114.2 - 0.19 11.7 0.3 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 Cobalt transport protein component CbiN NUDIX PF00293.23 CBK22115.2 - 4.5e-05 23.1 0.0 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ACPS PF01648.15 CBK22116.2 - 6.1e-20 71.1 0.0 7.8e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mre11_DNA_bind PF04152.9 CBK22116.2 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain Mito_morph_reg PF14972.1 CBK22116.2 - 0.096 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator Pkinase PF00069.20 CBK22117.2 - 1.6e-62 211.0 0.0 2.2e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22117.2 - 5.1e-32 110.9 0.2 2.6e-31 108.6 0.1 2.0 1 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK22117.2 - 3.7e-06 26.8 0.1 2.8e-05 23.9 0.0 2.3 1 1 2 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBK22117.2 - 0.0017 17.7 0.1 0.0062 15.9 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBK22117.2 - 0.008 15.2 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBK22117.2 - 0.022 13.5 0.1 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBK22117.2 - 0.062 12.2 0.0 0.35 9.7 0.0 2.2 3 0 0 3 3 3 0 Kinase-like Seadorna_VP7 PF07387.6 CBK22117.2 - 0.12 11.1 0.1 0.24 10.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Ras PF00071.17 CBK22118.2 - 8.5e-61 204.0 0.5 9.7e-61 203.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK22118.2 - 9.3e-22 77.7 0.1 1.4e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK22118.2 - 2.2e-16 59.5 0.0 2.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK22118.2 - 1.5e-06 27.5 0.1 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK22118.2 - 6.8e-06 26.0 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK22118.2 - 1.3e-05 24.6 0.2 3.7e-05 23.2 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBK22118.2 - 0.00014 21.1 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CBK22118.2 - 0.0017 17.5 0.1 0.0035 16.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 CBK22118.2 - 0.0074 15.8 0.1 0.052 13.0 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 CBK22118.2 - 0.0085 16.3 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CBK22118.2 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK22118.2 - 0.016 15.1 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.4 CBK22118.2 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 CBK22118.2 - 0.035 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CBK22118.2 - 0.055 12.7 0.0 0.66 9.2 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 CBK22118.2 - 0.059 12.9 0.1 0.083 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain YTH PF04146.10 CBK22118.2 - 0.084 12.4 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 YT521-B-like domain NACHT PF05729.7 CBK22118.2 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 CBK22118.2 - 0.1 11.5 0.2 0.51 9.3 0.1 2.0 1 1 1 2 2 2 0 Septin AAA_5 PF07728.9 CBK22118.2 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HECT PF00632.20 CBK22119.2 - 2.9e-46 158.0 0.0 4.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DNA_pol_B_2 PF03175.8 CBK22122.2 - 2.7e-07 29.6 11.3 0.00079 18.2 0.4 3.6 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral zf-C3HC4_2 PF13923.1 CBK22123.2 - 1.1e-09 38.0 11.1 2e-09 37.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK22123.2 - 2.1e-08 33.6 9.0 4e-08 32.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22123.2 - 5.1e-08 32.4 10.0 8.2e-08 31.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBK22123.2 - 1.3e-07 31.3 9.2 2.4e-07 30.4 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBK22123.2 - 1.2e-06 28.1 13.6 2.6e-06 27.1 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBK22123.2 - 2.6e-06 27.0 11.0 4.7e-06 26.2 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBK22123.2 - 1.2e-05 24.9 3.7 1.2e-05 24.9 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 CBK22123.2 - 0.00022 20.6 6.6 0.00045 19.6 4.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBK22123.2 - 0.073 12.8 4.9 0.14 11.9 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rotavirus_VP1 PF12289.3 CBK22123.2 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein zf-MIZ PF02891.15 CBK22123.2 - 0.2 11.2 13.0 0.42 10.1 9.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 CBK22123.2 - 0.68 9.7 5.4 1.5 8.7 2.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Rad50_zn_hook PF04423.9 CBK22123.2 - 1.2 8.7 6.9 3.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Metallothio_11 PF02066.10 CBK22123.2 - 2.2 8.1 6.0 5.1 7.0 4.2 1.6 1 0 0 1 1 1 0 Metallothionein family 11 zf-rbx1 PF12678.2 CBK22123.2 - 2.8 8.1 11.0 8.1 6.6 7.6 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DnaJ PF00226.26 CBK22124.2 - 1.8e-22 78.8 1.1 1.8e-22 78.8 0.8 3.7 3 1 0 3 3 3 1 DnaJ domain DUF2610 PF11020.3 CBK22124.2 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) DUF605 PF04652.11 CBK22124.2 - 2.3 7.5 17.1 2.8 7.2 11.9 1.2 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 CBK22125.2 - 3e-21 74.8 0.4 1.9e-15 56.2 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBK22125.2 - 6e-16 57.3 0.1 0.00032 20.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK22125.2 - 3.1e-11 42.3 0.9 0.0037 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK22125.2 - 2.3e-08 34.2 0.0 0.058 13.7 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK22125.2 - 0.00025 21.4 1.4 54 4.8 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK22125.2 - 0.00031 21.3 0.0 0.0075 16.9 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK22125.2 - 0.00041 20.3 0.0 2.1 8.7 0.0 3.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK22125.2 - 0.00046 20.0 3.0 0.86 9.5 0.1 3.6 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK22125.2 - 0.00096 18.7 0.1 0.36 10.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK22125.2 - 0.002 18.4 0.3 5.2 7.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK22125.2 - 0.0023 18.0 1.6 0.048 13.7 0.3 2.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CBK22125.2 - 0.0029 17.3 0.1 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK22125.2 - 0.0085 15.9 0.1 0.094 12.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 CBK22125.2 - 0.081 12.8 0.2 1 9.2 0.2 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 CBK22125.2 - 0.12 12.2 0.2 7 6.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_49 PF13896.1 CBK22126.2 - 5.1e-12 45.5 1.3 2.3e-07 30.2 0.2 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK22126.2 - 0.0005 19.2 0.0 0.00068 18.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2375 PF09558.5 CBK22126.2 - 0.14 11.9 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Adaptin_N PF01602.15 CBK22127.2 - 7e-130 433.8 9.8 8.3e-130 433.5 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK22127.2 - 7.6e-24 84.5 4.0 3.9e-21 75.7 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK22127.2 - 7.3e-17 61.4 2.7 9.4e-06 25.8 0.0 5.1 3 2 1 4 4 4 4 HEAT repeats HEAT PF02985.17 CBK22127.2 - 5.7e-10 38.4 11.0 0.26 11.4 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.2 CBK22127.2 - 8.2e-07 28.2 2.6 1.3e-05 24.3 0.3 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CBK22127.2 - 9.4e-05 22.7 3.9 0.26 11.8 0.0 5.0 4 3 1 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 CBK22127.2 - 0.00011 21.6 0.1 0.14 11.5 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 CBK22127.2 - 0.0053 16.5 0.6 8.9 6.3 0.0 4.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CBK22127.2 - 0.086 13.3 0.1 13 6.5 0.0 3.6 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Nucleoplasmin PF03066.10 CBK22127.2 - 0.24 10.9 6.6 0.4 10.1 4.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin DER1 PF04511.10 CBK22128.2 - 6.6e-18 64.9 2.3 8.1e-18 64.6 1.6 1.0 1 0 0 1 1 1 1 Der1-like family DUF3989 PF13150.1 CBK22128.2 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) 4F5 PF04419.9 CBK22129.2 - 6.1e-05 23.6 5.6 6.1e-05 23.6 3.9 2.4 2 1 0 2 2 2 1 4F5 protein family DUF3653 PF12375.3 CBK22129.2 - 0.53 10.5 3.9 0.92 9.7 2.7 1.5 1 1 0 1 1 1 0 Phage protein tRNA-synt_1c PF00749.16 CBK22130.2 - 7e-80 268.0 0.0 8.3e-80 267.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Thioredoxin_7 PF13899.1 CBK22131.2 - 5.6e-10 39.1 0.1 7.7e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK22131.2 - 4.4e-05 23.6 0.0 5.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK22131.2 - 0.0061 16.6 0.3 0.022 14.8 0.1 2.0 2 1 0 2 2 2 1 Thioredoxin-like TraF PF13728.1 CBK22131.2 - 0.011 15.2 0.1 0.17 11.3 0.0 2.1 1 1 1 2 2 2 0 F plasmid transfer operon protein Glyco_hydro_38 PF01074.17 CBK22132.2 - 4.4e-09 36.0 0.0 7.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_57 PF03065.10 CBK22132.2 - 0.03 13.2 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Gas_vesicle_C PF01304.12 CBK22132.2 - 0.56 9.8 3.9 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain XG_FTase PF03254.8 CBK22133.2 - 0.0014 17.2 0.0 0.0061 15.1 0.0 1.8 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase DUF4286 PF14114.1 CBK22134.2 - 0.085 13.1 0.2 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF4070 PF13282.1 CBK22134.2 - 0.68 9.4 3.6 13 5.2 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4070) Lactamase_B PF00753.22 CBK22135.2 - 3.6e-14 52.8 0.0 8.8e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta-Casp PF10996.3 CBK22135.2 - 1.1e-12 48.0 0.0 3.8e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 CBK22135.2 - 1.7e-12 47.3 0.0 3.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBK22135.2 - 2.3e-05 24.1 0.1 8.4e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CBK22135.2 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase PDEase_II PF02112.10 CBK22135.2 - 0.032 13.1 1.1 0.075 11.9 0.7 1.6 1 1 0 1 1 1 0 cAMP phosphodiesterases class-II Mito_fiss_reg PF05308.6 CBK22137.2 - 0.37 10.1 3.3 0.46 9.8 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator EF-hand_7 PF13499.1 CBK22138.2 - 2.3e-10 40.4 1.3 6.8e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBK22138.2 - 8e-10 37.3 0.2 0.00023 20.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBK22138.2 - 3.3e-09 35.8 1.2 0.00056 19.5 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBK22138.2 - 2e-08 33.7 1.8 0.0048 16.4 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK22138.2 - 0.00016 20.8 0.1 0.01 15.1 0.0 2.6 2 1 0 2 2 2 1 EF hand Pkinase PF00069.20 CBK22139.2 - 7.6e-63 212.0 0.0 9.1e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22139.2 - 1.1e-27 96.7 0.0 1.3e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 CBK22139.2 - 0.019 14.1 0.1 0.039 13.1 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase Kinase-like PF14531.1 CBK22139.2 - 0.021 13.8 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBK22139.2 - 0.022 14.4 0.0 0.25 11.0 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CBK22139.2 - 0.11 11.5 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 CBK22140.2 - 5.9e-40 136.5 0.0 8e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK22140.2 - 3.9e-05 23.8 0.7 0.0011 19.1 0.5 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBK22140.2 - 4.5e-05 22.6 0.0 7.5e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBK22140.2 - 0.00011 22.1 0.1 0.00026 20.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBK22140.2 - 0.00029 20.5 0.5 0.0017 18.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CBK22140.2 - 0.00031 19.7 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CBK22140.2 - 0.00048 19.5 1.3 0.41 10.0 0.2 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.1 CBK22140.2 - 0.00098 19.4 0.1 0.002 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK22140.2 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK22140.2 - 0.0022 18.7 0.0 0.0045 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK22140.2 - 0.0031 16.2 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 CBK22140.2 - 0.004 16.7 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBK22140.2 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22140.2 - 0.0059 16.6 0.2 0.1 12.5 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CBK22140.2 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBK22140.2 - 0.0095 15.1 0.1 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 CBK22140.2 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBK22140.2 - 0.037 13.7 0.6 0.17 11.6 0.3 2.1 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 CBK22140.2 - 0.045 13.5 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 CBK22140.2 - 0.055 12.9 0.1 0.96 8.8 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 CBK22140.2 - 0.067 12.6 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase NACHT PF05729.7 CBK22140.2 - 0.092 12.4 0.2 12 5.5 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CBK22140.2 - 0.14 11.2 0.1 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 CBK22140.2 - 0.16 11.0 1.2 1.6 7.7 0.1 2.1 1 1 1 2 2 2 0 KaiC Ribosomal_L1 PF00687.16 CBK22141.2 - 9.7e-39 132.9 0.0 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1935 PF09149.5 CBK22141.2 - 0.094 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Ran_BP1 PF00638.13 CBK22142.2 - 1.4e-38 131.6 2.6 2.2e-38 131.0 1.8 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 CBK22142.2 - 0.00016 21.2 0.8 0.0002 20.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 CBK22142.2 - 0.0013 18.4 0.4 0.0035 17.0 0.3 1.7 1 1 0 1 1 1 1 WH1 domain DERM PF14704.1 CBK22142.2 - 0.059 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Dermatopontin Flagellin_D3 PF08884.6 CBK22142.2 - 0.12 12.5 2.8 7.3 6.8 1.1 2.5 1 1 1 2 2 2 0 Flagellin D3 domain DUF563 PF04577.9 CBK22143.2 - 1.1e-19 71.2 1.3 8.8e-19 68.2 0.1 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF563) Collagen PF01391.13 CBK22144.2 - 7.6e-31 105.4 115.2 7.5e-09 35.0 19.3 4.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) NUC153 PF08159.7 CBK22145.2 - 3.5e-06 26.4 0.2 3.5e-06 26.4 0.2 2.5 3 0 0 3 3 3 1 NUC153 domain Antirestrict PF03230.8 CBK22145.2 - 0.098 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein CAGE1 PF15066.1 CBK22146.2 - 0.0072 14.8 0.0 0.0096 14.4 0.0 1.1 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family Rap1-DNA-bind PF09197.5 CBK22146.2 - 0.03 14.8 0.2 0.03 14.8 0.1 1.5 2 0 0 2 2 2 0 Rap1, DNA-binding CDT1 PF08839.6 CBK22146.2 - 0.069 13.0 0.1 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 DNA replication factor CDT1 like AKNA PF12443.3 CBK22146.2 - 0.12 12.3 0.8 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor RhoGAP PF00620.22 CBK22147.2 - 8.3e-23 80.6 0.1 1.1e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain MORN PF02493.15 CBK22148.2 - 0.076 12.7 23.6 0.079 12.7 0.2 5.9 7 0 0 7 7 7 0 MORN repeat GCFC PF07842.7 CBK22149.2 - 0.00055 19.3 0.0 0.14 11.5 0.0 2.7 3 0 0 3 3 3 2 GC-rich sequence DNA-binding factor-like protein Enkurin PF13864.1 CBK22149.2 - 0.073 13.2 0.1 0.33 11.1 0.0 2.0 1 1 1 2 2 2 0 Calmodulin-binding PUF PF00806.14 CBK22150.2 - 3.4e-06 26.2 0.0 0.078 12.4 0.0 4.0 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat TRA-1_regulated PF02343.11 CBK22150.2 - 0.0042 16.5 0.2 0.016 14.7 0.0 1.9 2 1 0 2 2 2 1 TRA-1 regulated protein R03H10.4 AAA_25 PF13481.1 CBK22151.2 - 1.1e-21 77.1 0.0 3e-20 72.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBK22151.2 - 1.5e-08 34.8 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22151.2 - 2e-07 31.2 0.0 6.2e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 CBK22151.2 - 2.1e-05 23.5 0.0 4.5e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_29 PF13555.1 CBK22151.2 - 0.00012 21.5 0.1 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBK22151.2 - 0.00084 19.6 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 CBK22151.2 - 0.0013 19.1 2.7 0.0028 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBK22151.2 - 0.002 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 CBK22151.2 - 0.0032 17.3 0.1 0.012 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBK22151.2 - 0.0038 16.8 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain KaiC PF06745.8 CBK22151.2 - 0.0046 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 KaiC cobW PF02492.14 CBK22151.2 - 0.0091 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CBK22151.2 - 0.011 15.2 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CBK22151.2 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 CBK22151.2 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CBK22151.2 - 0.016 15.1 0.4 0.047 13.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBK22151.2 - 0.031 15.1 1.2 0.059 14.1 0.1 2.1 2 1 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CBK22151.2 - 0.041 13.5 0.2 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 CBK22151.2 - 0.043 14.1 0.1 0.043 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 CBK22151.2 - 0.052 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRPRB PF09439.5 CBK22151.2 - 0.054 12.7 0.1 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 CBK22151.2 - 0.054 12.4 0.1 0.087 11.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 CBK22151.2 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CBK22151.2 - 0.087 12.5 0.2 0.22 11.2 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CBK22151.2 - 0.094 12.1 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 CBK22151.2 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 CBK22151.2 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase APS_kinase PF01583.15 CBK22151.2 - 0.11 12.1 0.1 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_21 PF13304.1 CBK22151.2 - 0.21 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MORN PF02493.15 CBK22152.2 - 6.9e-08 31.7 0.4 0.00082 18.9 0.0 2.3 2 0 0 2 2 2 2 MORN repeat AAA PF00004.24 CBK22153.2 - 7.1e-42 142.7 0.0 2.6e-41 140.9 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 CBK22153.2 - 5.9e-16 58.0 0.1 1.7e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.5 CBK22153.2 - 2.9e-10 39.8 0.0 1.8e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CBK22153.2 - 2.7e-08 34.0 0.0 1e-05 25.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBK22153.2 - 1.8e-07 30.4 0.0 5.9e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBK22153.2 - 4.4e-06 26.8 0.0 0.0044 17.0 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.12 CBK22153.2 - 9.6e-06 25.1 0.0 3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 CBK22153.2 - 1.1e-05 25.2 0.4 0.069 12.8 0.0 2.9 2 1 1 3 3 3 2 Archaeal ATPase AAA_14 PF13173.1 CBK22153.2 - 1.1e-05 25.2 0.0 3.3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK22153.2 - 1.8e-05 24.4 0.0 0.00023 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBK22153.2 - 2.8e-05 24.9 0.0 0.00015 22.5 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CBK22153.2 - 3.9e-05 23.1 0.1 0.12 11.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CBK22153.2 - 0.00024 20.1 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 CBK22153.2 - 0.00054 19.9 0.0 0.0038 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBK22153.2 - 0.00082 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK22153.2 - 0.0018 18.4 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CBK22153.2 - 0.0039 17.4 1.6 0.018 15.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 CBK22153.2 - 0.0068 15.1 0.0 0.026 13.2 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 CBK22153.2 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CBK22153.2 - 0.014 15.3 0.5 0.086 12.7 0.0 2.4 2 1 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 CBK22153.2 - 0.014 15.0 0.0 0.17 11.4 0.0 2.2 1 1 0 1 1 1 0 Bacterial dnaA protein DUF927 PF06048.6 CBK22153.2 - 0.014 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_19 PF13245.1 CBK22153.2 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CBK22153.2 - 0.016 14.8 0.0 0.65 9.6 0.0 2.5 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CBK22153.2 - 0.017 15.1 0.0 0.071 13.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CBK22153.2 - 0.019 14.0 0.0 4.2 6.4 0.0 2.5 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 CBK22153.2 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBK22153.2 - 0.032 13.7 0.0 0.21 11.0 0.0 2.3 2 1 1 3 3 3 0 Sigma-54 interaction domain CPT PF07931.7 CBK22153.2 - 0.036 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 CBK22153.2 - 0.044 13.3 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 CBK22153.2 - 0.045 13.7 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CBK22153.2 - 0.045 12.8 0.1 0.21 10.6 0.0 2.1 2 1 1 3 3 3 0 Zeta toxin TPR_1 PF00515.23 CBK22153.2 - 0.054 13.1 0.3 0.19 11.3 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat KAP_NTPase PF07693.9 CBK22153.2 - 0.057 12.3 0.0 1.7 7.5 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Peptidase_M28 PF04389.12 CBK22153.2 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M28 PhoH PF02562.11 CBK22153.2 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CBK22153.2 - 0.064 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 CBK22153.2 - 0.088 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bap31 PF05529.7 CBK22153.2 - 0.29 10.5 2.0 0.6 9.5 1.4 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ABC_tran PF00005.22 CBK22154.2 - 7.4e-74 246.5 0.0 1e-37 129.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK22154.2 - 2.4e-48 164.9 15.7 9e-24 84.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CBK22154.2 - 1.5e-16 61.2 1.5 0.016 15.1 0.0 5.0 4 1 1 5 5 5 4 AAA domain AAA_16 PF13191.1 CBK22154.2 - 2.1e-12 47.3 0.0 1.1e-05 25.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBK22154.2 - 4.3e-12 46.3 1.6 0.00036 20.6 0.2 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBK22154.2 - 8.9e-12 44.7 1.8 0.0016 17.7 0.0 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBK22154.2 - 3.3e-09 36.4 2.1 0.00012 21.5 0.1 3.6 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK22154.2 - 4.4e-09 35.7 0.0 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK22154.2 - 6.3e-09 35.2 0.2 0.0043 16.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 CBK22154.2 - 7.6e-09 35.8 1.6 0.00031 20.9 0.0 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBK22154.2 - 1.4e-08 35.5 1.9 0.0071 17.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CBK22154.2 - 9.6e-08 31.8 1.8 0.11 11.9 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain SbcCD_C PF13558.1 CBK22154.2 - 1.8e-07 30.9 4.0 0.0028 17.5 0.5 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 CBK22154.2 - 2.6e-07 29.5 1.5 0.0033 16.0 0.0 3.0 4 0 0 4 4 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 CBK22154.2 - 4.4e-07 29.6 0.4 0.069 12.7 0.0 4.5 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.9 CBK22154.2 - 2.3e-06 27.3 0.6 0.53 10.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK22154.2 - 1.1e-05 25.9 13.5 0.018 15.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.15 CBK22154.2 - 1.8e-05 23.6 13.1 0.012 14.3 0.0 3.2 3 0 0 3 3 2 2 G-protein alpha subunit Raftlin PF15250.1 CBK22154.2 - 1.8e-05 23.4 5.9 3.4e-05 22.5 4.1 1.3 1 0 0 1 1 1 1 Raftlin AAA_18 PF13238.1 CBK22154.2 - 2.1e-05 24.8 9.9 0.01 16.1 0.0 4.6 4 1 0 4 4 3 2 AAA domain MobB PF03205.9 CBK22154.2 - 7.3e-05 22.4 0.1 0.67 9.6 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBK22154.2 - 0.00015 21.6 0.1 0.49 10.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBK22154.2 - 0.00018 21.6 0.2 1 9.5 0.0 3.6 4 0 0 4 4 3 1 RNA helicase Miro PF08477.8 CBK22154.2 - 0.00023 21.6 0.2 0.6 10.6 0.0 3.7 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 CBK22154.2 - 0.00034 20.5 0.2 0.4 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBK22154.2 - 0.00035 19.5 0.1 0.15 10.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 CBK22154.2 - 0.00058 19.0 0.0 0.18 10.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CBK22154.2 - 0.00071 19.2 0.3 1.8 8.3 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 CBK22154.2 - 0.0015 17.9 0.3 6 6.2 0.0 3.9 5 0 0 5 5 3 0 IstB-like ATP binding protein PRK PF00485.13 CBK22154.2 - 0.0017 17.9 0.2 0.71 9.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 CBK22154.2 - 0.0018 18.1 0.0 2.1 8.2 0.0 3.3 3 1 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CBK22154.2 - 0.0018 17.7 0.0 0.081 12.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 CBK22154.2 - 0.0041 15.9 0.0 0.29 9.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein ATP_bind_1 PF03029.12 CBK22154.2 - 0.0042 16.6 0.3 0.42 10.1 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ycf1 PF05758.7 CBK22154.2 - 0.0064 14.2 0.7 0.0099 13.6 0.5 1.2 1 0 0 1 1 1 1 Ycf1 Sigma54_activat PF00158.21 CBK22154.2 - 0.0093 15.4 0.0 4.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF87 PF01935.12 CBK22154.2 - 0.014 15.2 6.6 0.21 11.3 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 NACHT PF05729.7 CBK22154.2 - 0.014 15.0 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.9 CBK22154.2 - 0.015 14.3 0.3 0.11 11.5 0.2 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 CBK22154.2 - 0.015 15.3 0.0 7 6.6 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBK22154.2 - 0.016 14.4 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 CBK22154.2 - 0.022 14.2 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 CBK22154.2 - 0.022 14.4 0.1 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Sec62 PF03839.11 CBK22154.2 - 0.031 13.6 1.3 0.067 12.5 0.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 T2SE PF00437.15 CBK22154.2 - 0.043 12.7 0.3 0.15 10.9 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein CDC45 PF02724.9 CBK22154.2 - 0.047 11.7 8.2 0.086 10.8 5.7 1.4 1 0 0 1 1 1 0 CDC45-like protein AAA_28 PF13521.1 CBK22154.2 - 0.052 13.5 0.2 3.3 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.5 CBK22154.2 - 1 9.3 20.7 2.3 8.1 11.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 CBK22154.2 - 1.5 8.1 17.9 0.09 12.1 8.8 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CBK22154.2 - 2 8.2 5.9 5 7.0 4.1 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3987 PF13148.1 CBK22154.2 - 4.3 5.8 20.5 1.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Tim54 PF11711.3 CBK22154.2 - 4.9 5.6 9.8 10 4.6 6.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 CBK22154.2 - 7.5 6.3 14.7 13 5.5 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 KH_1 PF00013.24 CBK22155.2 - 5.5e-48 160.4 13.4 2.6e-08 33.3 0.5 10.0 10 0 0 10 10 10 7 KH domain KH_3 PF13014.1 CBK22155.2 - 1.6e-26 91.4 2.7 0.00016 21.2 0.0 8.1 8 0 0 8 8 8 6 KH domain SLS PF14611.1 CBK22155.2 - 1.6e-15 57.1 10.6 0.012 14.9 0.0 7.7 2 2 6 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CBK22155.2 - 1.9e-10 40.1 14.9 0.021 14.4 0.0 6.1 6 1 0 6 6 6 3 KH domain Acyl_transf_1 PF00698.16 CBK22155.2 - 1.8e-05 24.2 8.1 0.0016 17.8 0.8 3.0 2 1 1 3 3 3 2 Acyl transferase domain KH_4 PF13083.1 CBK22155.2 - 0.00031 20.3 0.1 0.088 12.4 0.0 4.3 4 0 0 4 4 4 1 KH domain Secretin_N PF03958.12 CBK22155.2 - 0.0015 18.6 5.0 10 6.4 0.1 5.6 5 1 1 6 6 6 1 Bacterial type II/III secretion system short domain KH_5 PF13184.1 CBK22155.2 - 0.0028 17.4 9.1 0.51 10.1 0.2 5.1 6 0 0 6 6 6 1 NusA-like KH domain DUF1828 PF08861.5 CBK22155.2 - 0.023 14.3 2.3 27 4.5 0.1 4.6 5 0 0 5 5 5 0 Domain of unknown function DUF1828 DNA_pol3_beta_3 PF02768.10 CBK22155.2 - 3.1 7.4 14.1 3.9 7.0 0.2 4.4 3 2 2 5 5 5 0 DNA polymerase III beta subunit, C-terminal domain BRF1 PF07741.8 CBK22155.2 - 7.3 6.8 11.6 1.5 9.1 4.6 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain KH_1 PF00013.24 CBK22156.2 - 1.1e-14 53.7 0.7 3.3e-11 42.6 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBK22156.2 - 2.3e-05 23.9 3.0 6.5e-05 22.4 0.1 3.2 3 2 1 4 4 4 1 KH domain KH_2 PF07650.12 CBK22156.2 - 0.00065 19.2 2.7 0.0024 17.3 1.2 2.6 1 1 1 2 2 2 1 KH domain KH_5 PF13184.1 CBK22156.2 - 0.0012 18.5 4.7 0.066 13.0 0.1 3.1 3 0 0 3 3 3 2 NusA-like KH domain Phage_HK97_TLTM PF06120.6 CBK22156.2 - 0.0034 16.7 2.7 0.004 16.5 1.6 1.4 1 1 0 1 1 1 1 Tail length tape measure protein MIS13 PF08202.6 CBK22156.2 - 0.006 15.6 6.6 0.01 14.9 4.5 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family NPV_P10 PF05531.7 CBK22156.2 - 0.19 11.9 1.0 0.98 9.7 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 CBK22156.2 - 0.5 9.9 6.7 1.4 8.5 0.1 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.6 CBK22156.2 - 1.3 9.5 13.1 4.2 7.8 3.0 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.13 CBK22156.2 - 7.3 5.5 12.4 4.5 6.2 5.4 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Telomerase_RBD PF12009.3 CBK22158.2 - 2.4e-15 56.6 0.8 6.8e-15 55.1 0.6 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain HCV_NS5a_1b PF08301.8 CBK22158.2 - 0.081 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Pkinase PF00069.20 CBK22159.2 - 6.9e-53 179.4 0.0 8.6e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22159.2 - 7.5e-24 84.1 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBK22159.2 - 0.012 14.3 0.1 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBK22159.2 - 0.04 12.8 0.0 0.1 11.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 CBK22159.2 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phos_pyr_kin PF08543.7 CBK22160.2 - 2.1e-84 282.5 0.0 2.9e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CBK22160.2 - 8.4e-17 61.6 1.2 1.4e-16 60.8 0.9 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CBK22160.2 - 4.6e-07 29.2 0.0 7.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Spore_YtrH PF14034.1 CBK22160.2 - 0.076 12.9 0.2 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Sporulation protein YtrH Ribosomal_L19e PF01280.15 CBK22161.2 - 2.1e-56 189.8 11.7 2.7e-56 189.4 8.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e AcetylCoA_hyd_C PF13336.1 CBK22162.2 - 1.7e-41 141.4 0.0 2.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 CBK22162.2 - 8.5e-37 126.8 0.0 2.3e-36 125.4 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.18 CBK22162.2 - 0.052 12.7 0.1 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Coenzyme A transferase DNA_primase_lrg PF04104.9 CBK22163.2 - 1.6e-28 99.6 0.0 1.8e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CRM1_C PF08767.6 CBK22164.2 - 6.1e-53 179.7 4.1 3.8e-52 177.2 0.5 2.7 2 0 0 2 2 2 2 CRM1 C terminal Xpo1 PF08389.7 CBK22164.2 - 8.6e-22 77.6 4.1 4.2e-21 75.4 2.8 2.3 1 0 0 1 1 1 1 Exportin 1-like protein VHS PF00790.14 CBK22165.2 - 3.9e-21 75.1 0.0 8.1e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain uDENN PF03456.13 CBK22166.2 - 2.4e-12 46.6 0.1 3.3e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 uDENN domain DENN PF02141.16 CBK22167.2 - 6.9e-37 126.9 1.0 7.7e-37 126.8 0.7 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 CBK22167.2 - 6.2e-05 22.6 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CBK22167.2 - 0.00055 18.5 0.1 0.0018 16.8 0.1 1.7 1 1 1 2 2 2 1 Transport protein Avl9 NAD_binding_5 PF07994.7 CBK22168.2 - 6.8e-111 370.4 0.0 8e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CBK22168.2 - 2.4e-44 149.7 0.0 4.4e-44 148.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase CBFD_NFYB_HMF PF00808.18 CBK22169.2 - 4.6e-12 45.8 0.1 6.6e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NLE PF08154.7 CBK22169.2 - 0.093 12.7 0.4 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 NLE (NUC135) domain zf-RING_5 PF14634.1 CBK22170.2 - 0.0037 16.9 4.4 0.0037 16.9 3.1 3.5 3 0 0 3 3 3 1 zinc-RING finger domain Virul_Fac PF10139.4 CBK22170.2 - 0.0052 14.7 0.2 0.006 14.5 0.1 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor YbfN PF13982.1 CBK22170.2 - 0.013 15.6 1.9 1.2 9.3 0.9 2.6 2 0 0 2 2 2 0 YbfN-like lipoprotein GATA PF00320.22 CBK22170.2 - 0.016 14.5 0.5 0.016 14.5 0.4 3.1 2 1 1 3 3 3 0 GATA zinc finger Topoisom_I_N PF02919.10 CBK22170.2 - 0.095 11.9 2.8 0.17 11.1 1.9 1.5 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Pox_polyA_pol_C PF12629.2 CBK22170.2 - 0.12 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Lectin_N PF03954.9 CBK22170.2 - 0.17 11.2 2.3 0.34 10.3 0.4 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF2175 PF09943.4 CBK22170.2 - 0.6 10.1 7.2 7.5 6.6 1.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Pkinase PF00069.20 CBK22171.2 - 1.8e-45 155.1 0.0 2.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22171.2 - 7.2e-34 117.0 0.0 8.7e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PI-PLC-X PF00388.14 CBK22172.2 - 3.7e-05 23.1 0.0 0.00013 21.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HAD_2 PF13419.1 CBK22172.2 - 0.044 14.0 0.0 0.082 13.1 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RNA_helicase PF00910.17 CBK22173.2 - 1.1e-08 35.1 0.0 2.7e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CBK22173.2 - 0.096 12.2 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rep_2 PF01719.12 CBK22173.2 - 0.1 12.0 2.9 0.091 12.2 0.7 1.9 2 1 0 2 2 2 0 Plasmid replication protein Arch_ATPase PF01637.13 CBK22173.2 - 0.13 11.9 1.0 1.4 8.5 0.0 2.9 4 0 0 4 4 4 0 Archaeal ATPase DNA_pol_B_2 PF03175.8 CBK22174.2 - 1.4e-09 37.1 8.6 0.0013 17.5 0.2 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Ku_PK_bind PF08785.6 CBK22177.2 - 0.029 14.2 0.3 0.06 13.2 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Glyco_transf_49 PF13896.1 CBK22181.2 - 1e-18 67.5 4.8 7.7e-15 54.7 1.5 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Ku_PK_bind PF08785.6 CBK22183.2 - 0.028 14.2 0.3 0.059 13.2 0.2 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Bacteriocin_IIi PF11758.3 CBK22184.2 - 0.042 13.4 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin TRAPP PF04051.11 CBK22185.2 - 3.3e-29 101.3 0.1 4.8e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Rad60-SLD PF11976.3 CBK22185.2 - 2.2e-14 52.8 0.2 9.8e-14 50.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBK22185.2 - 9.9e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family SH3_9 PF14604.1 CBK22186.2 - 9.4e-18 63.5 2.1 1.8e-11 43.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CBK22186.2 - 4.1e-17 61.3 3.2 1.1e-11 43.9 0.1 3.1 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 CBK22186.2 - 2.8e-13 49.1 0.3 3.4e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CBK22186.2 - 2.1e-06 27.8 0.8 0.061 13.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.8 CBK22186.2 - 0.0053 16.2 0.7 2.6 7.6 0.0 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain CppA_C PF14507.1 CBK22186.2 - 0.28 11.4 1.9 0.58 10.3 0.0 2.3 2 1 1 3 3 3 0 CppA C-terminal Methyltransf_23 PF13489.1 CBK22187.2 - 4.3e-16 59.0 0.0 5.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK22187.2 - 7.6e-16 58.3 0.0 1.4e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK22187.2 - 3.8e-11 42.8 0.1 3.5e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBK22187.2 - 6.3e-09 36.2 0.2 9.9e-08 32.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBK22187.2 - 1.6e-08 34.0 0.0 3.7e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 CBK22187.2 - 5.4e-07 29.4 0.0 1.5e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 CBK22187.2 - 0.0008 19.7 0.1 0.0085 16.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22187.2 - 0.0061 17.1 0.1 0.12 12.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 CBK22187.2 - 0.068 11.4 0.0 0.1 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DNAPolymera_Pol PF11590.3 CBK22187.2 - 0.087 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol tRNA-synt_1d PF00750.14 CBK22190.2 - 4.3e-79 265.8 0.0 5.2e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBK22190.2 - 1.5e-30 105.6 0.0 6.4e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain DUF3456 PF11938.3 CBK22190.2 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP tRNA-synt_1e PF01406.14 CBK22190.2 - 0.075 12.1 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain FTCD_N PF07837.7 CBK22191.2 - 5.5e-72 241.0 0.0 8.7e-72 240.3 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 CBK22191.2 - 1.2e-61 207.3 0.0 2.4e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.9 CBK22191.2 - 9.6e-56 187.4 0.1 1.6e-55 186.6 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain Oxysterol_BP PF01237.13 CBK22192.2 - 6.7e-69 232.0 0.0 8.8e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein gag-asp_proteas PF13975.1 CBK22192.2 - 0.092 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease THUMP PF02926.12 CBK22193.2 - 3.9e-07 30.0 0.1 6.7e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 THUMP domain Atg14 PF10186.4 CBK22194.2 - 0.014 14.4 3.0 0.023 13.6 2.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Siah-Interact_N PF09032.6 CBK22194.2 - 0.053 13.5 3.2 0.095 12.7 2.2 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal GCV_H PF01597.14 CBK22195.2 - 7.9e-06 25.5 0.0 9.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Jiv90 PF14901.1 CBK22195.2 - 0.095 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone SET PF00856.23 CBK22196.2 - 2.4e-13 50.6 2.0 4.1e-11 43.4 0.0 2.8 2 1 0 2 2 2 2 SET domain CytochromB561_N PF09786.4 CBK22196.2 - 0.17 10.3 13.3 0.21 9.9 9.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal fn3 PF00041.16 CBK22197.2 - 2.1e-05 24.5 0.3 2.8 8.1 0.0 5.3 5 0 0 5 5 5 1 Fibronectin type III domain IncA PF04156.9 CBK22197.2 - 0.00039 20.0 0.6 0.00069 19.2 0.4 1.3 1 0 0 1 1 1 1 IncA protein EGF_2 PF07974.8 CBK22197.2 - 0.00062 19.8 6.6 0.00062 19.8 4.6 3.4 3 0 0 3 3 2 2 EGF-like domain hEGF PF12661.2 CBK22197.2 - 0.0043 17.0 8.2 0.048 13.7 0.8 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF DUF4446 PF14584.1 CBK22197.2 - 0.0052 16.6 1.5 0.011 15.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) EGF PF00008.22 CBK22197.2 - 0.01 15.8 16.4 0.37 10.8 4.2 3.0 2 0 0 2 2 2 2 EGF-like domain EphA2_TM PF14575.1 CBK22197.2 - 0.041 14.2 1.4 0.13 12.6 1.0 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S49_N PF08496.5 CBK22197.2 - 0.041 13.6 1.7 0.73 9.6 0.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal WTX PF09422.5 CBK22197.2 - 0.31 9.9 2.5 0.5 9.2 1.7 1.2 1 0 0 1 1 1 0 WTX protein Ycf1 PF05758.7 CBK22197.2 - 0.6 7.7 0.3 0.84 7.2 0.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF4355 PF14265.1 CBK22197.2 - 0.94 9.4 13.6 1.7 8.6 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1682 PF07946.9 CBK22197.2 - 5.7 5.6 10.4 9.2 5.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TPR_12 PF13424.1 CBK22198.2 - 1.6e-13 50.3 0.0 1.1e-08 34.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK22198.2 - 2.5e-11 42.5 0.0 0.00018 21.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBK22198.2 - 1.3e-10 40.3 0.0 2.7e-05 23.5 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBK22198.2 - 8e-10 38.2 0.0 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 CBK22198.2 - 2.4e-09 36.2 0.0 0.0024 17.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBK22198.2 - 7.3e-05 22.2 0.0 0.0019 17.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK22198.2 - 0.00077 19.4 0.0 1.6 9.0 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK22198.2 - 0.00087 19.5 0.0 0.003 17.8 0.0 2.0 2 1 0 2 2 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK22198.2 - 0.00094 19.2 0.1 0.1 12.7 0.0 2.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBK22198.2 - 0.0011 19.3 0.1 2.3 8.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 CBK22198.2 - 0.0015 17.9 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_10 PF13374.1 CBK22198.2 - 0.0056 16.5 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 CBK22198.2 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3808 PF10300.4 CBK22198.2 - 0.027 13.0 0.1 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_14 PF13428.1 CBK22198.2 - 0.051 14.2 0.1 6.1 7.7 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBK22198.2 - 0.088 11.9 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 Coatomer epsilon subunit TPR_16 PF13432.1 CBK22198.2 - 0.11 13.1 0.0 0.39 11.4 0.0 2.0 2 1 0 2 2 1 0 Tetratricopeptide repeat TruD PF01142.13 CBK22200.2 - 8.8e-63 212.2 0.0 3.2e-59 200.4 0.0 2.6 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) MRP-L47 PF06984.8 CBK22200.2 - 3.4e-27 94.1 0.4 3.4e-27 94.1 0.3 2.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) UDG PF03167.14 CBK22200.2 - 9.7e-23 80.3 0.0 1.9e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Methyltransf_10 PF05971.7 CBK22201.2 - 7.7e-57 192.7 0.1 1.1e-55 188.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF890) PrmA PF06325.8 CBK22201.2 - 7e-05 22.0 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CBK22201.2 - 0.0004 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK22201.2 - 0.00085 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBK22201.2 - 0.031 14.7 0.0 0.39 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Integrase_DNA PF02920.10 CBK22201.2 - 0.052 12.9 1.1 1.6 8.2 0.2 3.0 3 0 0 3 3 3 0 DNA binding domain of tn916 integrase SCP2 PF02036.12 CBK22202.2 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family AAA PF00004.24 CBK22203.2 - 4.9e-34 117.3 0.0 7e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBK22203.2 - 2.3e-05 24.3 0.0 4.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBK22203.2 - 0.00038 20.4 0.5 0.014 15.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBK22203.2 - 0.001 19.2 0.8 0.3 11.2 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK22203.2 - 0.0015 18.2 0.1 0.013 15.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBK22203.2 - 0.0035 18.1 0.0 0.0066 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK22203.2 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK22203.2 - 0.015 14.7 0.7 3.2 7.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBK22203.2 - 0.02 14.9 0.1 0.19 11.7 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBK22203.2 - 0.02 14.7 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBK22203.2 - 0.02 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 CBK22203.2 - 0.026 13.2 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 CBK22203.2 - 0.027 14.6 0.1 0.35 11.0 0.0 2.6 2 1 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 CBK22203.2 - 0.036 13.7 0.1 1 8.9 0.1 2.8 2 1 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 CBK22203.2 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBK22203.2 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBK22203.2 - 0.089 11.8 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 CBK22203.2 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF1664 PF07889.7 CBK22204.2 - 0.0016 18.2 5.9 0.0023 17.7 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Med21 PF11221.3 CBK22204.2 - 0.0023 17.9 1.3 0.0023 17.9 0.9 2.2 2 0 0 2 2 2 1 Subunit 21 of Mediator complex Mod_r PF07200.8 CBK22204.2 - 0.0036 17.2 18.1 0.0066 16.3 12.3 1.6 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 CBK22204.2 - 0.0037 15.9 17.5 0.0047 15.6 12.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 CBK22204.2 - 0.01 15.4 15.4 0.012 15.2 10.6 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CBK22204.2 - 0.015 14.2 12.6 0.019 13.8 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 CBK22204.2 - 0.03 14.3 13.9 0.04 13.9 9.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Reo_sigmaC PF04582.7 CBK22204.2 - 0.036 13.2 1.5 0.045 12.9 1.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CBK22204.2 - 0.14 12.2 12.7 0.26 11.4 8.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.8 CBK22204.2 - 0.15 11.4 12.7 0.04 13.3 2.0 2.2 1 1 1 2 2 2 0 fzo-like conserved region Mgr1 PF08602.5 CBK22204.2 - 0.22 10.4 5.5 0.25 10.3 3.8 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF3828 PF12883.2 CBK22204.2 - 0.29 11.0 5.6 0.26 11.1 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3828) DUF793 PF05633.6 CBK22204.2 - 0.36 9.5 6.8 0.44 9.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) DUF4446 PF14584.1 CBK22204.2 - 0.67 9.7 12.0 0.16 11.8 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF948 PF06103.6 CBK22204.2 - 0.98 9.3 5.2 1.9 8.3 3.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 CBK22204.2 - 1.2 7.5 13.5 1.4 7.2 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin_2 PF14523.1 CBK22204.2 - 1.2 9.1 14.2 0.59 10.2 4.5 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF2570 PF10828.3 CBK22204.2 - 1.3 8.6 16.9 0.39 10.3 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Nbl1_Borealin_N PF10444.4 CBK22204.2 - 1.4 8.3 9.3 5.3 6.4 1.3 2.7 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal ALMT PF11744.3 CBK22204.2 - 1.5 7.3 5.1 1.8 7.0 3.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4559 PF15112.1 CBK22204.2 - 2 7.4 14.6 5.3 6.1 9.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF972 PF06156.8 CBK22204.2 - 2.1 8.7 15.8 24 5.3 5.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) COG2 PF06148.6 CBK22204.2 - 2.3 8.0 10.5 3.5 7.4 5.6 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 CBK22204.2 - 2.6 7.9 18.5 3.6 7.4 12.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_Mu_Gam PF07352.7 CBK22204.2 - 2.7 7.4 15.7 0.17 11.4 2.5 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.10 CBK22204.2 - 2.8 7.0 10.3 3.5 6.7 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 CBK22204.2 - 4.4 6.2 20.3 11 4.9 14.1 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CBK22204.2 - 5.7 6.4 21.1 2.3 7.7 4.6 2.5 1 1 1 2 2 2 0 Septum formation initiator MutS_III PF05192.13 CBK22204.2 - 8.3 6.1 8.7 45 3.7 5.8 2.0 1 1 0 1 1 1 0 MutS domain III DUF2203 PF09969.4 CBK22204.2 - 8.4 6.6 9.2 91 3.3 6.8 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) EMP24_GP25L PF01105.19 CBK22204.2 - 8.6 6.0 14.1 27 4.3 9.7 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.17 CBK22204.2 - 8.9 6.3 16.9 98 3.0 11.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF607 PF04678.8 CBK22204.2 - 9 6.1 10.6 49 3.7 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF607 PseudoU_synth_1 PF01416.15 CBK22205.2 - 4.5e-26 91.3 0.0 1.7e-17 63.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 CBK22206.2 - 1.5e-57 193.4 0.0 1.9e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK22206.2 - 1.1e-18 67.8 0.0 1.9e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK22206.2 - 1.5e-13 50.3 0.1 2.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK22206.2 - 9.8e-06 24.8 0.1 2.1e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBK22206.2 - 5.9e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK22206.2 - 0.00094 19.1 0.0 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBK22206.2 - 0.0032 17.4 2.9 0.86 9.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBK22206.2 - 0.033 14.3 0.1 0.33 11.0 0.0 2.6 1 1 0 1 1 1 0 AAA domain DUF2450 PF10475.4 CBK22207.2 - 7.8e-29 100.4 3.4 3.8e-28 98.2 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 CBK22207.2 - 0.00021 20.9 2.8 0.00021 20.9 1.9 2.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 CBK22207.2 - 0.0035 17.0 2.5 0.0065 16.2 1.7 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 CBK22207.2 - 0.57 10.0 4.2 0.71 9.7 1.4 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M1 PF01433.15 CBK22208.2 - 1.6e-106 356.6 0.1 2.2e-106 356.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBK22208.2 - 1.9e-21 76.6 0.0 2.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBK22208.2 - 2e-15 56.9 0.0 4.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily XPA_N PF01286.13 CBK22209.2 - 0.005 16.4 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal IIGP PF05049.8 CBK22209.2 - 0.079 11.7 0.0 0.083 11.6 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Med3 PF11593.3 CBK22209.2 - 0.12 11.6 0.1 0.13 11.5 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MORN_2 PF07661.8 CBK22210.2 - 0.012 15.5 7.1 7.7 6.9 0.5 4.0 3 0 0 3 3 3 0 MORN repeat variant hSac2 PF12456.3 CBK22210.2 - 0.051 12.9 1.2 4.3 6.7 0.0 3.3 2 1 2 4 4 4 0 Inositol phosphatase WD40 PF00400.27 CBK22212.2 - 2e-34 116.2 5.6 6.3e-14 51.2 0.0 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat IKI3 PF04762.7 CBK22212.2 - 1.7e-05 22.8 0.0 7.9e-05 20.6 0.0 1.7 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 CBK22212.2 - 0.00024 20.9 0.0 0.0033 17.1 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CBK22212.2 - 0.00067 18.5 0.0 0.015 14.1 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 CBK22212.2 - 0.0016 16.6 0.5 0.42 8.6 0.1 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MMS1_N PF10433.4 CBK22212.2 - 0.0059 14.7 1.4 1.1 7.3 0.0 2.3 1 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.7 CBK22212.2 - 0.036 13.7 0.5 0.89 9.2 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CBK22212.2 - 0.085 12.3 0.1 16 5.0 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4303 PF14136.1 CBK22212.2 - 0.13 11.9 0.9 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) PSK_trans_fac PF07704.6 CBK22213.2 - 0.65 10.7 3.9 0.55 10.9 1.2 2.0 1 1 0 1 1 1 0 Rv0623-like transcription factor Glyco_transf_20 PF00982.16 CBK22214.2 - 5e-69 233.0 0.0 7.2e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CBK22214.2 - 1.2e-34 119.2 0.0 2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Acetyltransf_3 PF13302.1 CBK22215.2 - 2.6e-21 76.3 0.1 3.5e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK22215.2 - 1.8e-09 37.7 2.1 2.3e-09 37.3 1.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK22215.2 - 3.8e-09 36.4 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CBK22215.2 - 6.9e-08 32.4 0.2 9.7e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK22215.2 - 1.2e-06 28.2 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CBK22215.2 - 2.7e-05 24.2 0.1 6.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 CBK22215.2 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF2649 PF10854.3 CBK22215.2 - 0.12 12.5 0.3 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) TALPID3 PF15324.1 CBK22216.2 - 7.8 3.6 8.0 9.6 3.3 5.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Big_5 PF13205.1 CBK22217.2 - 2.1e-07 31.4 0.2 3.7e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain Sld5 PF05916.6 CBK22218.2 - 1.1e-14 54.5 0.6 1.6e-14 54.1 0.4 1.2 1 0 0 1 1 1 1 GINS complex protein CSD PF00313.17 CBK22219.2 - 9e-12 44.6 0.0 1.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain BRE1 PF08647.6 CBK22220.2 - 0.032 14.2 5.9 0.035 14.0 2.0 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF342 PF03961.8 CBK22220.2 - 0.035 12.5 3.7 0.037 12.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBK22220.2 - 0.08 13.2 4.2 0.094 13.0 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CBK22220.2 - 0.57 9.7 5.1 0.71 9.4 3.6 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBK22220.2 - 0.6 9.9 7.3 0.57 10.0 2.8 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cortex-I_coil PF09304.5 CBK22221.2 - 0.034 14.2 24.6 0.48 10.4 5.5 2.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil TMF_TATA_bd PF12325.3 CBK22221.2 - 0.22 11.2 27.1 2.2 8.0 8.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3708 PF12501.3 CBK22221.2 - 0.27 11.0 4.8 0.28 11.0 2.6 1.6 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter ParB PF08775.5 CBK22221.2 - 0.46 10.7 5.9 0.46 10.7 3.0 1.8 1 1 0 1 1 1 0 ParB family Laminin_II PF06009.7 CBK22221.2 - 0.51 10.1 18.9 0.064 13.0 3.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Lipoprotein_7 PF01540.11 CBK22221.2 - 0.91 8.5 10.0 7.2 5.5 7.0 1.9 1 1 0 1 1 1 0 Adhesin lipoprotein bZIP_1 PF00170.16 CBK22221.2 - 1.2 9.1 24.6 0.9 9.5 1.1 4.2 3 1 1 4 4 4 0 bZIP transcription factor Phage_GPO PF05929.6 CBK22221.2 - 1.3 8.2 12.7 0.58 9.3 7.2 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_MLP1_2 PF07926.7 CBK22221.2 - 1.9 8.2 29.2 7.2 6.3 1.8 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 CBK22221.2 - 2 8.3 27.9 0.5 10.2 5.9 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBK22221.2 - 2.1 7.8 31.0 13 5.3 16.4 2.2 1 1 1 2 2 2 0 IncA protein Rab5-bind PF09311.6 CBK22221.2 - 2.2 8.1 28.2 5.3 6.8 19.6 1.6 1 1 0 1 1 1 0 Rabaptin-like protein ATG16 PF08614.6 CBK22221.2 - 2.3 7.9 26.1 0.56 9.9 10.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 CBK22221.2 - 3.5 4.8 26.6 3.9 4.6 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF904 PF06005.7 CBK22221.2 - 3.9 7.8 31.0 99 3.3 9.2 4.0 2 2 0 2 2 2 0 Protein of unknown function (DUF904) MscS_porin PF12795.2 CBK22221.2 - 4.1 6.6 32.5 4.6 6.4 2.1 3.5 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 CBK22221.2 - 5.1 5.6 20.8 8.3 4.9 14.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Tup_N PF08581.5 CBK22221.2 - 7 6.9 18.2 1.4 9.1 7.6 2.8 1 1 1 2 2 2 0 Tup N-terminal Atg14 PF10186.4 CBK22221.2 - 7.2 5.4 24.8 0.3 10.0 3.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CBK22221.2 - 7.3 6.1 27.0 1.6 8.2 2.9 4.2 2 2 2 4 4 4 0 Septum formation initiator Phage_GP20 PF06810.6 CBK22221.2 - 7.4 6.0 21.4 5.2 6.5 2.8 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3450 PF11932.3 CBK22221.2 - 8.1 5.6 23.2 0.5 9.5 10.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NOT2_3_5 PF04153.13 CBK22222.2 - 1.3e-16 60.7 0.7 2.6e-16 59.7 0.5 1.6 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NIF PF03031.13 CBK22223.2 - 8.3e-19 67.7 0.0 1.9e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CBK22223.2 - 8e-05 22.7 0.0 0.00032 20.7 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBK22223.2 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain HAD_2 PF13419.1 CBK22223.2 - 0.022 14.9 1.5 0.82 9.8 0.0 3.5 3 1 0 4 4 4 0 Haloacid dehalogenase-like hydrolase THF_DHG_CYH PF00763.18 CBK22224.2 - 1.8e-19 69.8 0.6 6.1e-19 68.1 0.3 2.0 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CBK22224.2 - 4.3e-19 68.1 0.0 6.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DDRGK PF09756.4 CBK22224.2 - 0.016 14.6 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain Ribosomal_L7Ae PF01248.21 CBK22225.2 - 5.6e-25 86.6 0.0 6.4e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF_assoc_1 PF08355.7 CBK22226.2 - 1.7e-07 30.3 0.2 3.1e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 CBK22226.2 - 5.3e-05 22.8 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Bac_chlorC PF02043.12 CBK22227.2 - 0.00055 19.6 1.7 1 9.1 0.1 2.5 2 0 0 2 2 2 2 Bacteriochlorophyll C binding protein SAM_PNT PF02198.11 CBK22227.2 - 0.069 12.9 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF1215 PF06744.7 CBK22227.2 - 0.26 10.9 0.3 29 4.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) Peptidase_M16 PF00675.15 CBK22229.2 - 3.6e-33 114.4 0.1 4e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBK22230.2 - 0.00078 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain DEAD PF00270.24 CBK22232.2 - 2.5e-36 124.7 0.1 9.5e-36 122.8 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK22232.2 - 5.4e-23 80.6 0.1 1e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK22232.2 - 7.6e-08 32.4 0.1 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBK22232.2 - 2.2e-05 23.6 0.0 7.1e-05 21.9 0.0 1.8 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF187 PF02638.10 CBK22232.2 - 0.049 12.4 0.1 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 UDG PF03167.14 CBK22233.2 - 3e-05 23.5 0.0 0.0008 18.8 0.0 2.2 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Clathrin_lg_ch PF01086.12 CBK22234.2 - 1.6e-17 64.2 6.5 1.9e-17 63.9 4.5 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF2072 PF09845.4 CBK22234.2 - 0.083 12.8 1.8 0.13 12.2 1.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) LRR_8 PF13855.1 CBK22235.2 - 7.9e-36 121.6 51.5 4.1e-15 55.2 4.0 4.9 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 CBK22235.2 - 4.1e-35 118.8 53.5 2.2e-11 43.0 1.9 6.4 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBK22235.2 - 2.1e-17 60.4 33.9 0.0021 17.8 0.2 8.9 8 2 1 9 9 9 6 Leucine Rich Repeat LRR_7 PF13504.1 CBK22235.2 - 6.2e-12 43.6 31.0 0.1 12.8 0.1 9.3 9 1 1 10 10 10 6 Leucine rich repeat LRR_6 PF13516.1 CBK22235.2 - 2.5e-09 36.2 40.0 0.06 13.4 0.1 9.3 7 2 2 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.1 CBK22235.2 - 1.8e-07 30.9 7.6 0.0032 17.0 0.5 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.1 CBK22235.2 - 9e-07 28.6 0.9 3e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) DNA_pol_B_2 PF03175.8 CBK22237.2 - 4.5e-08 32.2 14.6 2.2e-05 23.3 10.1 2.8 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.8 CBK22238.2 - 1.2e-07 30.8 9.8 0.0011 17.7 1.1 3.4 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.8 CBK22239.2 - 2.3e-10 39.7 9.5 0.00095 17.9 0.1 3.6 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral AhpC-TSA PF00578.16 CBK22241.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK22241.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK22241.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin EMP24_GP25L PF01105.19 CBK22242.2 - 1e-28 100.2 3.2 1.2e-28 100.1 2.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FtsK_SpoIIIE_N PF12538.3 CBK22242.2 - 0.068 13.2 0.6 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 DNA transporter WEMBL PF05701.6 CBK22242.2 - 0.084 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TAA-Trp-ring PF15401.1 CBK22242.2 - 0.38 10.9 3.2 0.38 11.0 0.6 2.0 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin SNF2_N PF00176.18 CBK22243.2 - 2.6e-62 210.3 0.1 4e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK22243.2 - 7.8e-16 57.7 0.1 2.8e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22243.2 - 6.1e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK22243.2 - 0.0001 22.1 0.0 0.0009 19.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBK22243.2 - 0.00063 18.6 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ACBP PF00887.14 CBK22244.2 - 5e-17 61.3 0.0 9e-17 60.5 0.0 1.5 1 1 0 1 1 1 1 Acyl CoA binding protein DUF581 PF04570.9 CBK22246.2 - 2.9e-10 39.2 4.2 2.9e-10 39.2 2.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF581) PyrI_C PF02748.10 CBK22246.2 - 0.014 14.7 0.3 0.014 14.7 0.2 1.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HECT_2 PF09814.4 CBK22246.2 - 0.032 12.9 0.0 0.035 12.8 0.0 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RPAP2_Rtr1 PF04181.8 CBK22246.2 - 0.062 13.3 2.0 0.09 12.8 1.4 1.4 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-FCS PF06467.9 CBK22246.2 - 0.12 12.0 7.0 2.3 7.9 4.9 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.1 CBK22246.2 - 0.17 11.4 3.6 1.5 8.4 2.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain DSPc PF00782.15 CBK22247.2 - 2.3e-13 49.8 0.1 3.6e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SAMP PF05924.6 CBK22247.2 - 0.15 11.2 1.8 0.42 9.8 0.3 2.2 2 0 0 2 2 2 0 SAMP Motif IBR PF01485.16 CBK22248.2 - 0.2 11.5 1.1 1 9.2 0.1 2.1 1 1 1 2 2 2 0 IBR domain Ribosomal_L6e PF01159.14 CBK22250.2 - 1e-21 77.2 0.3 2.4e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L6e GHMP_kinases_N PF00288.21 CBK22252.2 - 0.012 15.6 2.5 0.028 14.4 0.6 2.5 2 1 1 3 3 3 0 GHMP kinases N terminal domain TPR_MLP1_2 PF07926.7 CBK22253.2 - 0.00034 20.3 6.8 0.00034 20.3 4.7 2.8 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 CBK22253.2 - 0.0035 17.3 4.0 0.0035 17.3 2.8 3.7 2 2 1 3 3 2 1 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 CBK22253.2 - 0.009 15.2 35.6 0.16 11.1 14.2 3.0 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 CBK22253.2 - 0.013 15.3 1.0 0.013 15.3 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Surfac_D-trimer PF09006.6 CBK22253.2 - 0.063 13.0 1.7 4.6 7.0 0.0 3.6 2 1 1 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Filament PF00038.16 CBK22253.2 - 0.18 11.2 29.3 0.11 11.9 4.8 2.5 2 0 0 2 2 2 0 Intermediate filament protein Shugoshin_N PF07558.6 CBK22253.2 - 0.18 11.5 12.0 1.3 8.8 0.5 4.2 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2207 PF09972.4 CBK22253.2 - 0.23 9.9 2.8 0.36 9.3 2.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ALIX_LYPXL_bnd PF13949.1 CBK22253.2 - 0.42 9.5 28.8 0.0092 14.9 3.6 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV KAR PF15222.1 CBK22253.2 - 0.77 9.8 4.6 0.39 10.8 1.2 2.0 2 0 0 2 2 2 0 Kidney androgen-regulated APG6 PF04111.7 CBK22253.2 - 1.5 7.7 35.7 0.94 8.4 5.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 CBK22253.2 - 1.7 8.1 39.8 0.77 9.3 9.1 3.5 2 2 1 3 3 3 0 IncA protein bZIP_1 PF00170.16 CBK22253.2 - 2.2 8.2 30.0 0.16 11.9 2.2 5.1 3 1 2 5 5 4 0 bZIP transcription factor DUF972 PF06156.8 CBK22253.2 - 2.9 8.2 32.8 1.3 9.4 2.3 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF972) MMPL PF03176.10 CBK22253.2 - 4.5 5.8 9.2 0.11 11.2 1.3 1.8 2 0 0 2 2 2 0 MMPL family CENP-F_leu_zip PF10473.4 CBK22253.2 - 4.6 7.1 38.9 11 5.8 1.4 3.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 CBK22253.2 - 5.1 7.0 32.3 0.34 10.8 3.6 3.7 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 CBK22253.2 - 6.9 5.7 13.7 16 4.5 0.1 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein BRCT PF00533.21 CBK22254.2 - 1.2e-24 86.2 0.6 5.5e-10 39.2 0.0 5.3 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBK22254.2 - 2.6e-19 68.8 0.1 4.1e-08 32.9 0.0 3.5 5 0 0 5 5 5 2 twin BRCT domain adh_short PF00106.20 CBK22255.2 - 5.5e-05 23.1 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBK22255.2 - 0.021 14.2 0.1 0.066 12.6 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Terminase_6 PF03237.10 CBK22255.2 - 0.038 12.7 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family Cpl-7 PF08230.6 CBK22255.2 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain Peptidase_C78 PF07910.8 CBK22256.2 - 4e-43 147.0 0.1 5.8e-43 146.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 CBK22256.2 - 0.023 13.8 0.4 0.39 9.8 0.1 2.2 1 1 0 2 2 2 0 Peptidase family C54 Y_phosphatase PF00102.22 CBK22258.2 - 3.3e-06 26.5 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBK22258.2 - 3.6e-06 26.5 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBK22258.2 - 0.042 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_S3Ae PF01015.13 CBK22259.2 - 2e-74 249.1 4.0 2.6e-74 248.8 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.17 CBK22259.2 - 0.0027 17.4 0.1 0.0027 17.4 0.1 2.0 3 0 0 3 3 3 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.11 CBK22259.2 - 0.04 13.2 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region zf-RING_2 PF13639.1 CBK22261.2 - 2e-13 49.9 8.8 4.9e-13 48.6 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CBK22261.2 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 CBK22261.2 - 2.9e-07 30.3 8.9 2.9e-07 30.3 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK22261.2 - 8.9e-07 28.5 7.2 8.9e-07 28.5 5.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBK22261.2 - 1.6e-06 27.6 6.7 1.6e-06 27.6 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22261.2 - 0.00015 21.3 10.4 0.00015 21.3 7.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBK22261.2 - 0.00078 19.5 9.2 0.0017 18.4 6.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBK22261.2 - 0.0056 16.3 6.8 0.012 15.2 1.2 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 CBK22261.2 - 0.042 13.0 3.2 0.064 12.4 2.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Phage_Gp23 PF10669.4 CBK22261.2 - 0.054 13.6 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RINGv PF12906.2 CBK22261.2 - 0.055 13.5 3.8 0.14 12.2 2.6 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CBK22261.2 - 0.055 13.4 10.4 0.093 12.7 4.9 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 CBK22261.2 - 0.067 13.0 6.1 0.22 11.4 4.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 CBK22261.2 - 1.7 8.2 12.1 0.17 11.4 4.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Mito_carr PF00153.22 CBK22262.2 - 7.2e-60 198.7 5.7 4.7e-25 87.1 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Polysacc_synt_C PF14667.1 CBK22262.2 - 0.39 10.4 4.8 0.38 10.5 0.5 2.9 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain eIF-5a PF01287.15 CBK22264.2 - 1.5e-14 53.6 2.7 2.3e-14 53.0 1.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CBK22264.2 - 0.0016 18.2 0.1 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CBK22264.2 - 0.0082 15.8 0.4 0.024 14.3 0.3 1.9 1 0 0 1 1 1 1 KOW motif Pec_lyase PF09492.5 CBK22264.2 - 0.046 12.8 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 Pectic acid lyase Imm16 PF15565.1 CBK22264.2 - 0.13 12.1 0.6 0.21 11.4 0.4 1.2 1 0 0 1 1 1 0 Immunity protein 16 Ribosomal_L7Ae PF01248.21 CBK22265.2 - 5.4e-27 93.1 0.0 6.8e-27 92.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK22265.2 - 0.0025 17.6 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CBK22265.2 - 0.032 13.9 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Adenosine_kin PF04008.9 CBK22265.2 - 0.048 13.1 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase Porin_3 PF01459.17 CBK22266.2 - 4.4e-16 59.0 3.0 5.4e-16 58.7 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin OB_NTP_bind PF07717.11 CBK22267.2 - 3.4e-25 88.0 0.0 7.8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBK22267.2 - 6.7e-21 74.2 0.6 1.7e-20 72.9 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBK22267.2 - 8.9e-10 38.3 0.0 2.7e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22267.2 - 1.4e-09 37.6 0.1 1.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK22267.2 - 7.9e-06 26.0 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBK22267.2 - 0.00015 21.6 0.9 0.11 12.3 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Collagen PF01391.13 CBK22267.2 - 0.00049 19.5 5.4 0.00049 19.5 3.8 3.9 3 1 1 4 4 3 2 Collagen triple helix repeat (20 copies) T2SE PF00437.15 CBK22267.2 - 0.0043 15.9 0.0 0.0084 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 CBK22267.2 - 0.0054 17.0 0.8 0.027 14.7 0.1 2.4 2 1 1 3 3 3 1 ABC transporter KaiC PF06745.8 CBK22267.2 - 0.012 14.7 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.4 CBK22267.2 - 0.015 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CBK22267.2 - 0.033 14.1 0.3 0.43 10.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK22267.2 - 0.042 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBK22267.2 - 0.047 14.0 0.1 0.047 14.0 0.0 2.6 2 1 1 3 3 3 0 AAA domain Miro PF08477.8 CBK22267.2 - 0.049 14.1 0.2 0.18 12.3 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein SRP54 PF00448.17 CBK22267.2 - 0.05 13.0 1.0 0.33 10.3 0.5 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 CBK22267.2 - 0.057 13.4 0.1 0.76 9.8 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain NB-ARC PF00931.17 CBK22267.2 - 0.061 12.1 0.0 0.061 12.1 0.0 1.6 2 0 0 2 2 1 0 NB-ARC domain PhoH PF02562.11 CBK22267.2 - 0.062 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein AAA_29 PF13555.1 CBK22267.2 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CBK22267.2 - 0.16 11.6 1.5 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase UFC1 PF08694.6 CBK22268.2 - 1.1e-72 242.7 0.1 1.3e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CBK22268.2 - 1.2e-06 28.0 0.3 1.8e-06 27.4 0.2 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBK22268.2 - 0.0031 17.3 0.4 0.0098 15.7 0.3 1.6 1 1 1 2 2 2 1 RWD domain Prok-E2_B PF14461.1 CBK22268.2 - 0.07 12.8 0.2 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B PepSY_TM_2 PF13703.1 CBK22269.2 - 0.13 12.4 0.0 0.13 12.4 0.0 2.1 3 0 0 3 3 3 0 PepSY-associated TM helix Mito_carr PF00153.22 CBK22270.2 - 3.7e-35 119.4 4.3 9e-18 63.7 0.1 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein Got1 PF04178.7 CBK22271.2 - 1.1e-19 70.6 19.0 1.7e-19 70.0 13.2 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family QCR10 PF09796.4 CBK22271.2 - 0.021 14.4 0.5 0.05 13.2 0.4 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF912 PF06024.7 CBK22271.2 - 0.1 12.6 1.8 0.12 12.4 0.0 2.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_S30 PF04758.9 CBK22272.2 - 3.7e-27 93.8 6.3 5.5e-27 93.2 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.18 CBK22272.2 - 1.8e-21 75.2 0.0 2.6e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK22272.2 - 1e-09 37.9 0.0 1.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK22272.2 - 8.1e-05 22.7 0.7 0.00038 20.6 0.5 1.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 CBK22272.2 - 0.00047 19.8 0.4 0.00079 19.1 0.3 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBK22272.2 - 0.001 18.9 0.4 0.0039 17.0 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.20 CBK22274.2 - 1.8e-12 46.9 0.2 2.6e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22274.2 - 2.3e-10 40.0 0.1 2.8e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBK22274.2 - 4.5e-09 35.9 0.0 7.7e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBK22274.2 - 9.9e-07 28.0 0.0 4.5e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 CBK22274.2 - 3.3e-05 23.2 0.8 4.2e-05 22.8 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 CBK22274.2 - 3.9e-05 23.4 0.0 0.00056 19.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBK22274.2 - 0.00014 21.1 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CBK22274.2 - 0.036 13.6 0.2 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 CBK22274.2 - 0.088 11.4 0.1 0.2 10.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) WD40 PF00400.27 CBK22275.2 - 5.5e-07 29.2 1.2 1.7 8.6 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 CBK22275.2 - 3.7e-05 23.5 0.2 4.3 7.0 0.0 4.3 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBK22275.2 - 0.0065 16.1 2.3 2.1 8.0 0.0 3.7 3 1 1 4 4 4 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 CBK22275.2 - 0.069 12.8 3.3 0.33 10.6 0.1 2.8 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Nucleoporin2 PF04096.9 CBK22276.2 - 3.6e-24 85.1 0.0 5e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin autopeptidase BCA_ABC_TP_C PF12399.3 CBK22278.2 - 0.59 9.8 2.4 1 9.0 0.2 2.4 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter Nuc_sug_transp PF04142.10 CBK22279.2 - 1.6e-14 53.5 4.2 4.4e-14 52.1 2.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CBK22279.2 - 0.0036 17.3 11.9 0.016 15.2 5.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family zf-like PF04071.7 CBK22280.2 - 0.029 14.0 9.5 0.057 13.1 6.6 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain Glyco_transf_15 PF01793.11 CBK22280.2 - 0.058 12.3 0.2 0.083 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SDH_alpha PF03313.10 CBK22281.2 - 1.3e-80 270.4 8.3 2.1e-80 269.7 5.7 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CBK22281.2 - 2.1e-30 105.8 0.4 1.2e-19 70.8 0.0 2.5 1 1 1 2 2 2 2 Serine dehydratase beta chain TPR_11 PF13414.1 CBK22282.2 - 5.2e-36 122.1 7.7 1e-15 57.1 0.1 4.2 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CBK22282.2 - 4.7e-28 95.6 9.4 3.1e-05 23.3 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBK22282.2 - 8.2e-24 81.5 11.3 0.0024 17.6 0.0 6.7 7 1 0 7 7 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 CBK22282.2 - 4.2e-13 48.0 4.3 0.047 13.4 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK22282.2 - 1.6e-12 47.6 1.2 0.2 12.3 0.0 4.5 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBK22282.2 - 1.8e-12 46.4 6.4 0.00018 21.4 0.1 5.5 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK22282.2 - 2.1e-12 46.4 1.8 0.0007 20.0 0.0 5.6 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK22282.2 - 1.6e-11 43.9 4.6 0.0006 19.6 0.0 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK22282.2 - 4.1e-10 39.8 0.7 0.17 12.2 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBK22282.2 - 1.5e-09 37.5 1.1 0.035 13.9 0.0 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBK22282.2 - 2.6e-09 36.1 3.9 0.52 10.2 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK22282.2 - 6.5e-05 22.9 3.2 0.021 14.9 0.1 3.1 2 2 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBK22282.2 - 0.0017 18.6 7.7 20 5.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK22282.2 - 0.0021 17.9 5.2 4 7.4 0.0 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CBK22282.2 - 0.022 14.6 8.7 0.14 12.1 0.3 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 CBK22282.2 - 0.055 13.3 1.0 4.2 7.1 0.1 3.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 CBK22282.2 - 0.092 12.6 2.7 6.2 6.7 0.0 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 CBK22282.2 - 1.4 9.8 4.8 32 5.7 0.1 4.0 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat Cofilin_ADF PF00241.15 CBK22283.2 - 5.5e-30 103.8 0.0 1.2e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2420 PF10336.4 CBK22283.2 - 0.013 15.0 0.5 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Ras PF00071.17 CBK22284.2 - 7.8e-25 87.1 0.0 1.6e-24 86.1 0.0 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CBK22284.2 - 1.2e-13 51.5 0.0 3.7e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein EF-hand_6 PF13405.1 CBK22284.2 - 1.9e-08 33.5 0.5 0.0013 18.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF_assoc_2 PF08356.7 CBK22284.2 - 3.2e-08 33.2 0.0 8.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.27 CBK22284.2 - 2.3e-06 26.4 0.1 0.039 13.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBK22284.2 - 5.5e-06 26.4 0.0 0.016 15.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK22284.2 - 0.00012 21.2 3.3 0.11 11.8 0.1 2.7 2 0 0 2 2 2 2 EF hand Arf PF00025.16 CBK22284.2 - 0.00035 19.8 0.4 0.0042 16.3 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBK22284.2 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_8 PF13833.1 CBK22284.2 - 0.0079 15.7 0.3 2.8 7.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair GTP_EFTU PF00009.22 CBK22284.2 - 0.014 14.8 0.3 0.19 11.1 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MORN PF02493.15 CBK22286.2 - 6.6e-05 22.3 19.7 0.0044 16.6 4.1 3.4 3 0 0 3 3 3 2 MORN repeat Lipase_3 PF01764.20 CBK22287.2 - 9.2e-18 64.2 0.0 1.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBK22287.2 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 CBK22287.2 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPT PF03151.11 CBK22288.2 - 1.9e-10 40.6 19.1 6.1e-10 38.9 7.0 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBK22288.2 - 2.4e-05 24.3 18.3 0.001 19.1 5.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBK22288.2 - 2.5e-05 23.3 16.5 5.6e-05 22.1 11.5 1.5 1 1 0 1 1 1 1 UAA transporter family DUF4190 PF13828.1 CBK22288.2 - 0.27 10.8 6.2 0.98 9.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Ribosomal_L1 PF00687.16 CBK22289.2 - 8.1e-47 159.3 6.2 9.4e-47 159.1 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CPSase_L_D2 PF02786.12 CBK22290.2 - 2.8e-72 242.4 0.0 4.7e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK22290.2 - 6.8e-40 135.6 0.0 1.6e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK22290.2 - 2.1e-34 117.7 0.0 4.5e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK22290.2 - 2.9e-18 65.2 0.2 6.1e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK22290.2 - 1.8e-09 36.7 0.0 3.5e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK22290.2 - 4.1e-08 32.7 0.1 5.3e-07 29.1 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK22290.2 - 4.9e-08 32.9 0.0 1.4e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK22290.2 - 8.2e-08 31.8 0.1 3.4e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK22290.2 - 6.9e-05 22.2 0.0 0.00016 21.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK22290.2 - 0.00079 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK22290.2 - 0.0025 17.0 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK22290.2 - 0.004 16.8 0.4 0.013 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK22290.2 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK22290.2 - 0.016 15.5 0.0 0.47 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK22290.2 - 0.044 13.8 0.1 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK22290.2 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK22290.2 - 0.046 13.1 0.0 0.16 11.4 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK22290.2 - 0.075 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain LRR_8 PF13855.1 CBK22291.2 - 0.043 13.5 2.5 2.6 7.8 0.2 2.3 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 CBK22291.2 - 1.3 8.6 5.1 12 5.7 3.1 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) RF-1 PF00472.15 CBK22292.2 - 4.1e-19 68.4 2.4 6.8e-19 67.7 1.6 1.4 1 1 0 1 1 1 1 RF-1 domain Exonuc_VII_S PF02609.11 CBK22293.2 - 0.0014 18.3 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit zf-DHHC PF01529.15 CBK22295.2 - 1.5e-22 79.7 12.9 3.3e-22 78.7 9.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1011 PF06237.7 CBK22295.2 - 0.15 11.9 4.4 0.56 10.1 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1011) PIP49_N PF14875.1 CBK22295.2 - 0.4 10.3 7.9 0.05 13.2 2.3 1.8 1 1 1 2 2 2 0 N-term cysteine-rich ER, FAM69 CH PF00307.26 CBK22297.2 - 2.8e-24 85.2 3.6 8.7e-12 45.0 0.0 3.5 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBK22297.2 - 8.5e-06 25.3 0.0 0.035 13.7 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain AAA_13 PF13166.1 CBK22297.2 - 0.0021 16.6 43.8 0.0035 15.8 12.9 2.6 1 1 1 2 2 2 2 AAA domain DUF948 PF06103.6 CBK22297.2 - 0.056 13.3 9.6 5.4 6.9 0.3 4.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cation_ATPase_N PF00690.21 CBK22297.2 - 0.093 12.2 0.5 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus MCPsignal PF00015.16 CBK22297.2 - 0.16 11.5 5.7 0.85 9.1 2.1 2.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Thioredoxin PF00085.15 CBK22298.2 - 7.7e-64 211.9 0.0 8.6e-31 105.7 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CBK22298.2 - 1.1e-33 116.5 0.0 4.2e-24 85.3 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK22298.2 - 2.5e-13 50.1 2.5 7.3e-05 22.9 0.0 4.5 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK22298.2 - 1e-12 47.9 0.1 3.7e-05 23.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK22298.2 - 5.3e-11 42.4 0.1 1.8e-05 24.7 0.0 4.1 4 1 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.5 CBK22298.2 - 3.5e-08 33.1 0.5 0.00073 19.0 0.0 3.2 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 CBK22298.2 - 8.5e-08 31.9 0.1 0.0067 16.1 0.0 2.8 2 1 1 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 CBK22298.2 - 1.1e-05 25.3 0.1 0.9 9.4 0.0 3.6 3 1 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 CBK22298.2 - 0.0047 16.4 0.1 0.74 9.3 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_4 PF13462.1 CBK22298.2 - 0.021 14.8 0.5 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.1 CBK22298.2 - 0.062 13.1 0.0 1.8 8.4 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin domain HyaE PF07449.6 CBK22298.2 - 0.07 13.0 0.3 9.7 6.1 0.0 3.6 5 0 0 5 5 5 0 Hydrogenase-1 expression protein HyaE DUF3053 PF11254.3 CBK22299.2 - 0.06 12.5 0.1 0.06 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Sec7_N PF12783.2 CBK22300.2 - 1.5e-11 43.9 1.2 1.7e-11 43.8 0.8 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.15 CBK22301.2 - 1.5e-31 109.5 0.4 2e-31 109.1 0.3 1.2 1 0 0 1 1 1 1 Sec7 domain Ribosomal_S4 PF00163.14 CBK22302.2 - 3.6e-20 72.1 0.4 7.2e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBK22302.2 - 6.3e-13 47.9 0.4 6.3e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.7 CBK22302.2 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger Met_10 PF02475.11 CBK22303.2 - 4.8e-27 94.8 0.0 1.2e-26 93.5 0.0 1.6 1 1 1 2 2 2 1 Met-10+ like-protein MTS PF05175.9 CBK22303.2 - 1.6e-06 27.6 0.1 9.9e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBK22303.2 - 2.2e-06 28.1 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK22303.2 - 2.4e-06 27.5 0.0 4.2e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK22303.2 - 4.3e-06 26.3 0.0 7.2e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBK22303.2 - 8.3e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 CBK22303.2 - 2.4e-05 23.1 0.1 9.5e-05 21.2 0.0 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.15 CBK22303.2 - 0.00013 21.0 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 CBK22303.2 - 0.00073 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 CBK22303.2 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 CBK22303.2 - 0.036 13.1 0.2 0.095 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase ATLF PF07737.6 CBK22303.2 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain AhpC-TSA PF00578.16 CBK22304.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK22304.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK22304.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF461 PF04314.8 CBK22305.2 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF461) GCC2_GCC3 PF07699.8 CBK22307.2 - 0.00034 20.1 2.6 0.00076 19.0 1.8 1.5 1 0 0 1 1 1 1 GCC2 and GCC3 NCD3G PF07562.9 CBK22307.2 - 0.0032 17.1 2.8 0.0068 16.0 2.0 1.5 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR eIF-3_zeta PF05091.7 CBK22308.2 - 2.4e-77 260.7 1.5 2.7e-77 260.5 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_L27 PF01016.14 CBK22309.2 - 4.6e-35 119.2 0.2 5.4e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein ArfGap PF01412.13 CBK22310.2 - 3.6e-26 91.2 0.1 8.7e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.20 CBK22310.2 - 2.9e-17 62.7 0.0 1e-16 60.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain ANTH PF07651.11 CBK22310.2 - 9.5e-17 60.6 0.1 1.7e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 ANTH domain Pkinase_Tyr PF07714.12 CBK22310.2 - 9.2e-09 34.7 0.0 4.7e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22310.2 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ENTH PF01417.15 CBK22310.2 - 0.048 13.5 0.1 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 ENTH domain Pkinase_Tyr PF07714.12 CBK22311.2 - 8.9e-64 215.0 0.0 1.1e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBK22311.2 - 9.9e-54 182.2 0.0 1.3e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Nitroreductase PF00881.19 CBK22313.2 - 5.3e-31 107.6 0.0 7.8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.1 CBK22313.2 - 0.015 14.4 0.4 1.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Putative TM nitroreductase DEAD PF00270.24 CBK22314.2 - 2.2e-18 66.3 0.0 9.1e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK22314.2 - 8.8e-18 63.9 0.0 2.1e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK22314.2 - 1.7e-15 57.3 0.0 3.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-HC5HC2H_2 PF13832.1 CBK22316.2 - 6.4e-24 84.0 7.7 1e-23 83.4 5.3 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBK22316.2 - 2.7e-15 56.2 7.4 2.7e-15 56.2 5.1 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.17 CBK22316.2 - 0.008 15.8 6.0 0.008 15.8 4.1 2.3 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Adaptin_N PF01602.15 CBK22317.2 - 5.6e-148 493.5 15.4 6.7e-148 493.2 10.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK22317.2 - 1.8e-26 93.0 6.0 8.1e-24 84.4 0.2 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK22317.2 - 3e-20 72.3 2.8 2.9e-08 33.8 0.0 6.5 2 2 5 7 7 7 4 HEAT repeats HEAT PF02985.17 CBK22317.2 - 5e-11 41.7 7.5 0.0039 17.1 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat Cnd3 PF12719.2 CBK22317.2 - 6.6e-07 28.5 1.6 0.00031 19.8 0.0 3.1 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 CBK22317.2 - 1.7e-06 27.6 0.7 0.33 10.8 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBK22317.2 - 0.0002 21.7 1.8 5.3 7.6 0.0 5.6 6 1 0 6 6 4 1 HEAT-like repeat CLASP_N PF12348.3 CBK22317.2 - 0.00021 20.7 1.8 0.44 9.8 0.0 3.7 2 1 1 3 3 3 1 CLASP N terminal FANCI_S3 PF14677.1 CBK22317.2 - 0.0068 15.8 0.3 0.061 12.7 0.1 2.5 2 0 0 2 2 2 1 FANCI solenoid 3 UNC45-central PF11701.3 CBK22317.2 - 0.028 14.0 2.9 1 9.0 0.0 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.1 CBK22317.2 - 0.058 13.3 2.2 1.5 8.7 0.1 3.8 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N PF14664.1 CBK22317.2 - 0.2 10.1 6.8 0.39 9.2 0.7 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Sec7_N PF12783.2 CBK22317.2 - 0.27 10.6 4.3 0.12 11.8 0.3 2.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal V-ATPase_H_C PF11698.3 CBK22317.2 - 0.67 9.8 4.5 11 6.0 0.0 4.3 4 1 0 4 4 4 0 V-ATPase subunit H FANCI_S2 PF14676.1 CBK22317.2 - 0.71 9.7 4.4 8 6.3 0.1 3.9 3 2 1 4 4 4 0 FANCI solenoid 2 NPR3 PF03666.8 CBK22317.2 - 3.7 5.9 9.0 4.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Astro_capsid PF03115.9 CBK22317.2 - 4.3 5.4 12.3 8.2 4.5 8.6 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Gar1 PF04410.9 CBK22318.2 - 1.2e-23 83.3 0.1 1.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_60s PF00428.14 CBK22319.2 - 1.6e-24 86.0 14.8 1.9e-24 85.8 10.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CBK22319.2 - 3.1 7.3 7.8 4 6.9 5.3 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 CBK22319.2 - 6.5 5.8 7.7 6.3 5.8 5.0 1.2 1 1 0 1 1 1 0 Myc amino-terminal region Ribosomal_S4e PF00900.15 CBK22320.2 - 1.1e-28 98.6 0.7 2.6e-28 97.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.24 CBK22320.2 - 0.0004 19.9 2.0 0.0004 19.9 1.4 3.4 4 0 0 4 4 4 1 KOW motif S4 PF01479.20 CBK22320.2 - 0.012 15.0 0.3 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 S4 domain zf-rbx1 PF12678.2 CBK22321.2 - 1.1e-28 99.0 9.7 1.6e-28 98.6 6.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBK22321.2 - 1e-14 54.0 11.9 7.9e-13 48.0 8.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBK22321.2 - 7.9e-08 32.0 11.3 8.3e-06 25.5 7.9 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBK22321.2 - 4.2e-05 23.1 8.2 7.8e-05 22.2 0.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK22321.2 - 0.00017 21.5 0.3 0.00017 21.5 0.2 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22321.2 - 0.0011 18.6 10.3 0.0044 16.6 0.5 2.6 1 1 3 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBK22321.2 - 0.016 15.1 1.0 0.016 15.1 0.7 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.3 CBK22321.2 - 0.018 14.5 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 CBK22321.2 - 0.035 14.2 8.2 0.21 11.7 0.5 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 CBK22321.2 - 0.18 11.5 11.1 7.2 6.4 7.7 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 CBK22321.2 - 0.55 10.2 9.0 22 5.1 6.2 2.1 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 CBK22321.2 - 2.8 7.9 10.6 46 4.1 7.4 2.2 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 CBK22321.2 - 4 7.2 6.2 1.3 8.7 0.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Baculo_RING PF05883.6 CBK22321.2 - 4.9 6.9 6.5 23 4.8 4.5 2.0 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 CBK22321.2 - 5 6.8 10.7 1.2 8.9 0.7 2.3 2 0 0 2 2 2 0 PHD-finger EMP24_GP25L PF01105.19 CBK22322.2 - 1.8e-23 83.2 0.2 1.9e-23 83.1 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cep57_CLD_2 PF14197.1 CBK22322.2 - 0.045 13.6 1.0 0.074 13.0 0.7 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2664 PF10867.3 CBK22322.2 - 0.061 13.9 1.1 0.097 13.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) RIO1 PF01163.17 CBK22323.2 - 2.8e-06 26.8 0.0 4e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 RIO1 family Herpes_IE1 PF07340.6 CBK22323.2 - 0.026 12.9 0.1 0.03 12.7 0.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein FtsA PF14450.1 CBK22323.2 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsA Suf PF05843.9 CBK22324.2 - 1.3e-08 34.8 0.1 1.6e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBK22324.2 - 0.025 14.4 0.2 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBK22324.2 - 0.042 14.4 0.0 0.092 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S7 PF00177.16 CBK22324.2 - 0.079 12.5 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S7p/S5e TPR_15 PF13429.1 CBK22324.2 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.15 CBK22324.2 - 0.14 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat Fis1_TPR_C PF14853.1 CBK22324.2 - 0.21 11.4 1.4 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Synaptobrevin PF00957.16 CBK22325.2 - 3.4e-11 42.5 1.5 6.2e-11 41.7 1.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBK22325.2 - 1.4e-09 37.3 0.3 4.4e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain potato_inhibit PF00280.13 CBK22326.2 - 9.2e-19 67.3 0.1 1.3e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.3 CBK22326.2 - 0.00063 19.4 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family Ribosomal_L18e PF00828.14 CBK22327.2 - 3.1e-24 85.7 0.0 4.4e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 OprF PF05736.6 CBK22327.2 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Ribosomal_60s PF00428.14 CBK22328.2 - 1.6e-24 86.0 14.8 1.9e-24 85.8 10.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CBK22328.2 - 3.1 7.3 7.8 4 6.9 5.3 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 CBK22328.2 - 6.5 5.8 7.7 6.3 5.8 5.0 1.2 1 1 0 1 1 1 0 Myc amino-terminal region Carboxyl_trans PF01039.17 CBK22329.2 - 1.2e-149 498.8 0.9 1.8e-149 498.2 0.6 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CBK22329.2 - 4.1e-111 372.3 0.0 5.8e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 CBK22329.2 - 8.9e-48 162.3 0.5 5.8e-47 159.6 0.0 2.4 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_C13 PF01650.13 CBK22329.2 - 3.1e-32 111.9 0.0 6.6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C13 family CPSase_L_chain PF00289.17 CBK22329.2 - 2.2e-26 92.1 0.1 5.5e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK22329.2 - 3.2e-24 84.9 0.1 2.8e-23 81.9 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CBK22329.2 - 5.2e-13 49.1 0.0 1.6e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBK22329.2 - 2.8e-11 42.7 0.0 6.7e-09 34.9 0.0 3.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CBK22329.2 - 1.4e-10 40.6 0.0 6.3e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBK22329.2 - 0.00025 20.5 0.0 0.0009 18.6 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK22329.2 - 0.0022 17.3 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBK22329.2 - 0.069 13.0 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain IncA PF04156.9 CBK22329.2 - 3.2 7.3 15.0 0.3 10.6 1.1 2.5 2 0 0 2 2 2 0 IncA protein Peptidase_C1 PF00112.18 CBK22330.2 - 1.5e-97 325.8 23.4 3e-55 187.5 4.0 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Octopine_DH PF02317.12 CBK22330.2 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Peptidase_C1_2 PF03051.10 CBK22330.2 - 0.48 8.8 8.0 0.89 8.0 0.6 3.0 3 0 0 3 3 3 0 Peptidase C1-like family XG_FTase PF03254.8 CBK22331.2 - 0.019 13.4 0.2 0.57 8.6 0.0 2.3 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Mei5 PF10376.4 CBK22331.2 - 0.42 10.1 6.1 3.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Double-strand recombination repair protein CDP-OH_P_transf PF01066.16 CBK22336.2 - 1.9e-19 69.8 1.9 1.9e-19 69.8 1.3 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Form-deh_trans PF09163.6 CBK22336.2 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane TPT PF03151.11 CBK22337.2 - 1.3e-20 73.5 14.6 1.3e-20 73.5 10.1 2.3 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CBK22337.2 - 3.9e-15 56.0 24.8 1.1e-07 31.8 10.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBK22337.2 - 1.3e-09 37.4 23.3 2.4e-09 36.5 16.1 1.4 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CBK22337.2 - 3.6e-07 30.3 14.9 0.0011 19.1 0.7 2.7 1 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF3796 PF12676.2 CBK22337.2 - 0.17 12.0 9.6 0.39 10.9 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Multi_Drug_Res PF00893.14 CBK22337.2 - 5.6 7.5 10.5 4.5 7.8 0.9 3.5 3 2 0 3 3 3 0 Small Multidrug Resistance protein UPF0546 PF10639.4 CBK22337.2 - 8.3 6.2 12.1 10 5.9 0.9 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 Phosducin PF02114.11 CBK22338.2 - 0.0066 15.1 0.0 0.007 15.1 0.0 1.0 1 0 0 1 1 1 1 Phosducin DUF4239 PF14023.1 CBK22339.2 - 2.2e-05 23.9 0.0 2.4e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Prominin PF05478.6 CBK22339.2 - 0.023 12.2 0.2 0.026 12.0 0.1 1.0 1 0 0 1 1 1 0 Prominin GatB_Yqey PF02637.13 CBK22339.2 - 0.13 11.9 1.3 0.26 11.0 0.2 1.9 1 1 1 2 2 2 0 GatB domain DNA_pol_phi PF04931.8 CBK22339.2 - 0.15 9.8 5.4 0.17 9.6 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF843 PF05814.6 CBK22339.2 - 6 6.7 6.8 49 3.8 0.0 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) NYD-SP28_assoc PF14775.1 CBK22341.2 - 0.021 14.5 3.1 0.13 11.9 0.3 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Glyco_hydro_20 PF00728.17 CBK22342.2 - 1.6e-76 257.7 3.8 7.5e-76 255.5 2.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CBK22342.2 - 2.7e-24 86.2 0.0 6.4e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CBK22342.2 - 1.2e-07 32.2 0.0 2.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CFIA_Pcf11 PF11526.3 CBK22342.2 - 0.0076 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Glyco_hydro_97 PF10566.4 CBK22342.2 - 0.02 13.9 0.3 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycoside hydrolase 97 DEAD PF00270.24 CBK22344.2 - 1.7e-11 43.9 0.0 5.2e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK22344.2 - 7.6e-10 38.5 0.1 1.7e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CBK22344.2 - 0.084 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nol1_Nop2_Fmu PF01189.12 CBK22346.2 - 1e-38 133.3 0.0 2e-20 73.3 0.0 2.9 1 1 1 3 3 3 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBK22346.2 - 4.1e-10 39.9 0.0 8.6e-10 38.8 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CBK22346.2 - 0.00017 21.6 0.0 0.00083 19.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22346.2 - 0.056 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBK22346.2 - 0.07 12.7 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 CBK22347.2 - 4.4e-53 178.7 0.6 2.9e-34 117.8 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CBK22347.2 - 2.4e-30 103.9 0.5 2.5e-25 87.8 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBK22347.2 - 6.5e-21 73.4 4.1 4.9e-20 70.6 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 CBK22347.2 - 1.6e-19 70.2 0.0 3.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Shikimate_DH PF01488.15 CBK22347.2 - 0.1 12.6 1.4 9.3 6.3 0.3 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-RING_2 PF13639.1 CBK22348.2 - 5.4e-14 51.7 6.1 5.4e-14 51.7 4.2 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK22348.2 - 4.8e-09 36.1 4.3 1.3e-08 34.8 2.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBK22348.2 - 5.2e-09 35.9 6.6 1.4e-08 34.5 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK22348.2 - 3.2e-08 33.1 4.4 3.2e-08 33.1 3.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBK22348.2 - 3.7e-08 32.9 5.3 1e-07 31.5 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22348.2 - 6.8e-07 28.8 2.5 1.4e-06 27.9 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.17 CBK22348.2 - 5.6e-06 25.9 0.2 9.7e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 PA domain zf-Apc11 PF12861.2 CBK22348.2 - 4.2e-05 23.3 3.2 0.00011 21.9 2.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBK22348.2 - 0.005 16.5 2.0 0.018 14.7 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 CBK22348.2 - 0.027 13.9 6.7 0.027 13.9 2.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 CBK22348.2 - 0.028 14.1 3.3 0.071 12.8 2.3 1.8 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 CBK22348.2 - 0.038 13.8 5.5 0.11 12.4 3.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CBK22348.2 - 0.052 13.1 3.6 0.12 12.0 2.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CBK22348.2 - 0.09 12.8 4.1 0.2 11.7 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 CBK22348.2 - 0.18 11.5 6.4 1.3 8.7 0.4 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBK22348.2 - 0.35 10.8 6.9 0.26 11.2 2.8 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_6 PF14835.1 CBK22348.2 - 0.91 9.3 4.0 4 7.3 1.0 2.9 3 0 0 3 3 3 0 zf-RING of BARD1-type protein AAA_12 PF13087.1 CBK22349.2 - 3.7e-44 150.5 0.0 8.1e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK22349.2 - 2e-11 43.9 0.1 1.8e-07 31.0 0.0 3.0 1 1 2 3 3 3 3 AAA domain Viral_helicase1 PF01443.13 CBK22349.2 - 3.2e-06 26.8 0.0 0.012 15.1 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CBK22349.2 - 0.00098 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 CBK22349.2 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CBK22349.2 - 0.0064 16.2 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 CBK22349.2 - 0.062 12.9 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase LUC7 PF03194.10 CBK22350.2 - 1.8e-54 184.9 7.4 1.8e-54 184.9 5.1 1.5 1 1 0 1 1 1 1 LUC7 N_terminus HrcA PF01628.16 CBK22350.2 - 0.021 14.4 1.4 0.033 13.7 1.0 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF2524 PF10732.4 CBK22350.2 - 0.22 11.6 4.0 0.19 11.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) V_ATPase_I PF01496.14 CBK22350.2 - 1.4 6.6 4.2 1.7 6.4 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adaptin_N PF01602.15 CBK22351.2 - 1.9e-88 297.1 6.5 2.3e-88 296.8 4.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK22351.2 - 3.3e-15 56.3 8.1 6.8e-12 45.5 1.0 3.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 CBK22351.2 - 5.5e-12 45.5 0.9 1e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 CBK22351.2 - 8.5e-10 38.7 2.5 4.4e-06 26.8 0.3 4.9 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.17 CBK22351.2 - 2e-06 27.3 7.4 0.75 10.0 0.0 6.0 7 1 1 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 CBK22351.2 - 2.1e-05 24.8 8.7 0.041 14.3 0.0 5.6 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 CBK22351.2 - 0.02 14.7 0.3 2.4 8.1 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Cut8_M PF14483.1 CBK22351.2 - 0.1 12.4 0.3 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Cut8 dimerisation domain ABC_tran PF00005.22 CBK22352.2 - 4.5e-50 169.5 1.5 9.2e-38 129.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CBK22352.2 - 1.3e-46 159.2 17.6 2e-27 96.3 0.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CBK22352.2 - 1.8e-11 44.5 2.4 0.026 14.5 0.1 4.1 3 1 1 4 4 4 3 AAA domain DUF258 PF03193.11 CBK22352.2 - 1.4e-09 37.3 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBK22352.2 - 2.1e-09 37.6 0.7 0.00032 20.8 0.3 3.4 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK22352.2 - 4.1e-09 36.6 0.1 0.0013 18.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBK22352.2 - 5.9e-09 35.3 0.1 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK22352.2 - 8.3e-07 29.8 4.6 0.0064 17.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 CBK22352.2 - 1.5e-06 27.6 0.5 0.025 13.8 0.0 3.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBK22352.2 - 9.4e-06 26.0 15.2 0.016 15.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Raftlin PF15250.1 CBK22352.2 - 1.1e-05 24.1 6.4 2.1e-05 23.2 4.4 1.3 1 0 0 1 1 1 1 Raftlin AAA_25 PF13481.1 CBK22352.2 - 1.6e-05 24.3 0.3 0.22 10.9 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CBK22352.2 - 2.2e-05 24.1 0.1 0.061 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBK22352.2 - 2.5e-05 23.8 1.6 0.099 12.0 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 CBK22352.2 - 3.5e-05 23.5 0.1 0.4 10.3 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CBK22352.2 - 8.5e-05 22.2 0.4 1.1 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CBK22352.2 - 0.00011 22.4 0.9 1.2 9.3 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CBK22352.2 - 0.00015 21.7 0.0 0.44 10.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_11 PF13086.1 CBK22352.2 - 0.00017 21.2 1.1 0.0011 18.6 0.6 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBK22352.2 - 0.00024 20.0 0.1 0.14 10.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 CBK22352.2 - 0.00037 20.6 0.3 1.7 8.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase ABC_ATPase PF09818.4 CBK22352.2 - 0.00037 19.2 0.7 0.0013 17.4 0.0 2.1 3 0 0 3 3 2 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 CBK22352.2 - 0.00055 19.6 0.8 0.98 9.2 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBK22352.2 - 0.0006 19.3 0.0 0.074 12.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CBK22352.2 - 0.0007 19.4 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC45 PF02724.9 CBK22352.2 - 0.00075 17.6 5.9 0.0012 16.9 4.1 1.3 1 0 0 1 1 1 1 CDC45-like protein AAA_18 PF13238.1 CBK22352.2 - 0.00097 19.4 11.7 0.0094 16.2 0.0 4.0 3 1 0 3 3 2 2 AAA domain Ycf1 PF05758.7 CBK22352.2 - 0.0013 16.5 0.3 0.0019 16.0 0.2 1.2 1 0 0 1 1 1 1 Ycf1 Miro PF08477.8 CBK22352.2 - 0.0016 18.9 0.1 0.54 10.7 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 CBK22352.2 - 0.0024 16.6 17.9 0.067 11.8 0.0 3.2 3 0 0 3 3 2 2 G-protein alpha subunit ArgK PF03308.11 CBK22352.2 - 0.0031 16.3 0.0 0.26 10.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 CBK22352.2 - 0.0037 16.9 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF1510 PF07423.6 CBK22352.2 - 0.0087 15.4 15.1 0.017 14.4 10.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Sec62 PF03839.11 CBK22352.2 - 0.0088 15.4 2.3 0.019 14.4 1.6 1.5 1 0 0 1 1 1 1 Translocation protein Sec62 KAP_NTPase PF07693.9 CBK22352.2 - 0.0097 14.9 0.4 0.06 12.3 0.2 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_14 PF13173.1 CBK22352.2 - 0.01 15.7 0.1 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 CBK22352.2 - 0.015 15.1 5.9 0.19 11.5 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 CBK22352.2 - 0.018 14.5 0.2 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 CBK22352.2 - 0.019 14.3 0.1 5.5 6.3 0.0 2.9 4 0 0 4 4 2 0 IstB-like ATP binding protein PRK PF00485.13 CBK22352.2 - 0.027 14.0 5.6 0.64 9.5 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.1 CBK22352.2 - 0.03 14.2 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sigma54_activat PF00158.21 CBK22352.2 - 0.033 13.6 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 CBK22352.2 - 0.034 13.0 0.1 0.13 11.1 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AP-5_subunit_s1 PF15001.1 CBK22352.2 - 0.071 13.0 0.4 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 CT47 PF15623.1 CBK22352.2 - 0.17 11.6 13.9 0.27 10.9 9.7 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 AIF_C PF14721.1 CBK22352.2 - 0.68 10.1 5.5 3.2 8.0 2.7 2.6 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.17 CBK22352.2 - 0.72 8.8 5.7 0.89 8.4 0.1 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 CBK22352.2 - 0.78 9.5 16.7 1.3 8.8 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 CBK22352.2 - 1.3 8.8 7.8 2.4 8.0 5.1 1.6 2 0 0 2 2 1 0 GAGA binding protein-like family Vfa1 PF08432.5 CBK22352.2 - 2.1 8.3 23.4 1.3 9.0 13.9 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 CBK22352.2 - 2.5 6.6 11.7 4.3 5.8 8.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3987 PF13148.1 CBK22352.2 - 2.6 6.5 20.6 1.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) DDHD PF02862.12 CBK22352.2 - 4.5 6.9 7.4 8.9 6.0 5.1 1.4 1 0 0 1 1 1 0 DDHD domain Laminin_II PF06009.7 CBK22353.2 - 0.013 15.2 4.6 0.013 15.2 3.2 4.6 2 1 3 5 5 5 0 Laminin Domain II Reo_sigmaC PF04582.7 CBK22353.2 - 0.018 14.2 19.7 0.12 11.5 2.1 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF869 PF05911.6 CBK22353.2 - 0.8 7.8 64.6 0.082 11.1 19.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Pox_A_type_inc PF04508.7 CBK22353.2 - 3.6 7.6 12.9 1 9.3 0.1 5.5 4 1 1 5 5 5 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 CBK22353.2 - 7.6 6.4 25.4 0.068 13.0 0.6 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) RRF PF01765.14 CBK22354.2 - 1.5e-26 92.8 17.3 3.1e-26 91.7 12.0 1.5 1 1 0 1 1 1 1 Ribosome recycling factor MtrG PF04210.8 CBK22354.2 - 0.041 13.5 2.2 0.048 13.3 0.5 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1319 PF07028.6 CBK22354.2 - 0.066 13.4 9.0 0.089 12.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF1204 PF06721.6 CBK22354.2 - 0.094 11.9 9.2 0.19 10.9 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3810 PF12725.2 CBK22354.2 - 0.23 10.2 3.0 0.29 10.0 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TPR_MLP1_2 PF07926.7 CBK22354.2 - 0.37 10.5 7.8 0.76 9.5 5.3 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 CBK22354.2 - 0.45 10.9 3.9 1.1 9.7 1.4 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0154 PF03672.8 CBK22354.2 - 1.7 8.3 8.4 0.34 10.5 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PRKCSH-like PF12999.2 CBK22354.2 - 2.3 7.7 6.4 3.1 7.3 4.5 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF1515 PF07439.6 CBK22354.2 - 2.7 7.8 7.3 5.1 6.9 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) YtxH PF12732.2 CBK22354.2 - 6.2 7.2 8.7 14 6.1 6.0 1.6 1 1 0 1 1 1 0 YtxH-like protein RNase_H2-Ydr279 PF09468.5 CBK22355.2 - 1.2e-29 103.4 8.4 7.4e-28 97.6 5.8 2.0 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) PP2C PF00481.16 CBK22356.2 - 1.2e-73 247.6 0.0 1.4e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBK22356.2 - 4.4e-05 22.9 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Syntaxin PF00804.20 CBK22357.2 - 0.033 14.3 2.3 0.033 14.3 1.6 2.5 2 1 0 2 2 2 0 Syntaxin SpoIIIAH PF12685.2 CBK22357.2 - 0.062 12.7 4.8 0.11 11.9 3.3 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein SRP_SPB PF02978.14 CBK22357.2 - 0.45 10.7 5.4 0.91 9.8 3.8 1.9 1 1 0 1 1 1 0 Signal peptide binding domain zf-DBF PF07535.7 CBK22357.2 - 0.65 9.7 5.3 1.5 8.5 1.7 2.3 2 0 0 2 2 2 0 DBF zinc finger Cache_2 PF08269.6 CBK22357.2 - 1.4 8.9 5.4 8.2 6.4 0.1 2.6 2 1 0 2 2 2 0 Cache domain SieB PF14163.1 CBK22357.2 - 1.4 8.4 19.8 0.67 9.5 1.9 3.1 2 2 1 3 3 3 0 Superinfection exclusion protein B LRR_4 PF12799.2 CBK22360.2 - 0.61 9.7 2.7 8.6 6.1 0.5 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 CBK22361.2 - 2.4e-65 220.2 0.0 2.7e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22361.2 - 4.1e-43 147.3 0.0 4.9e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22361.2 - 1.8e-09 36.9 0.0 2.3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK22361.2 - 9.1e-07 28.1 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK22361.2 - 0.016 14.5 0.0 0.056 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CBK22361.2 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SH2_2 PF14633.1 CBK22362.2 - 0.00055 19.0 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 CBK22362.2 - 0.04 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Fer2 PF00111.22 CBK22363.2 - 0.013 15.2 0.2 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF208 PF02677.9 CBK22363.2 - 0.12 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 eIF-3c_N PF05470.7 CBK22365.2 - 2.5e-52 177.7 0.4 3.2e-52 177.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CBK22365.2 - 1.5e-06 28.4 0.0 4.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 PCI domain eIF-3c_N PF05470.7 CBK22366.2 - 5.7e-30 103.9 10.9 7e-30 103.6 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus tRNA-synt_1e PF01406.14 CBK22366.2 - 0.0051 15.9 0.9 0.0067 15.5 0.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain MbeB_N PF04837.7 CBK22366.2 - 0.039 14.0 0.2 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF1786 PF08735.5 CBK22366.2 - 0.074 12.2 0.2 0.091 11.9 0.2 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) IlvC PF01450.14 CBK22366.2 - 0.56 10.1 2.9 4.6 7.1 0.1 2.1 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain EXOSC1 PF10447.4 CBK22367.2 - 7e-22 77.1 1.8 1.3e-21 76.2 0.4 1.9 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CBK22367.2 - 3.7e-10 38.9 0.0 7e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region WD40 PF00400.27 CBK22368.2 - 2.5e-34 115.8 5.7 9.5e-11 41.1 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK22368.2 - 0.00034 18.8 0.1 1.5 6.8 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Sushi PF00084.15 CBK22368.2 - 0.093 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Sushi domain (SCR repeat) PIP5K PF01504.13 CBK22369.2 - 1.7e-71 240.3 0.1 2.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_6 PF13405.1 CBK22370.2 - 8.7e-12 43.8 2.8 1.6e-05 24.3 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBK22370.2 - 1.5e-11 42.7 6.4 3.2e-07 29.1 0.6 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBK22370.2 - 1.8e-10 40.8 7.7 5.4e-09 36.0 1.3 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CBK22370.2 - 1.5e-08 34.0 4.1 2.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK22370.2 - 6.8e-07 28.3 6.2 1.6e-06 27.1 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 CBK22370.2 - 0.0075 15.9 1.6 0.099 12.3 0.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBK22370.2 - 0.028 14.4 0.5 0.093 12.7 0.1 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.7 CBK22370.2 - 0.15 12.3 0.7 5.4 7.2 0.1 2.4 1 1 2 3 3 3 0 p25-alpha Topoisom_I PF01028.15 CBK22371.2 - 2.7e-80 268.8 1.3 4.6e-80 268.0 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 CBK22371.2 - 2.3e-52 177.4 0.3 2.4e-51 174.0 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 CBK22371.2 - 2.8e-29 100.5 0.1 7.7e-29 99.1 0.1 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-grasp_5 PF13549.1 CBK22373.2 - 5.3e-55 186.0 0.1 7.4e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding_2 PF13380.1 CBK22373.2 - 6.6e-21 74.6 0.0 1.7e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 CBK22373.2 - 1.1e-08 35.4 0.1 6.8e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Med3 PF11593.3 CBK22373.2 - 4.2 6.4 9.8 6.1 5.9 6.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-MYND PF01753.13 CBK22374.2 - 8.8e-14 51.0 14.6 1.1e-13 50.8 10.1 1.1 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 CBK22374.2 - 0.00042 19.9 14.1 0.00087 18.8 7.5 2.1 2 0 0 2 2 2 1 HIT zinc finger NDUFB10 PF10249.4 CBK22374.2 - 0.049 13.7 0.2 0.061 13.4 0.1 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Trm112p PF03966.11 CBK22374.2 - 0.063 13.6 0.8 0.1 12.9 0.6 1.3 1 0 0 1 1 1 0 Trm112p-like protein zf-Mss51 PF13824.1 CBK22374.2 - 0.2 11.5 8.7 0.3 10.9 6.0 1.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Prok-RING_1 PF14446.1 CBK22374.2 - 2.1 8.1 9.1 20 5.0 0.0 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 CBK22374.2 - 3 5.3 4.6 3.1 5.3 3.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-FCS PF06467.9 CBK22374.2 - 7.1 6.3 14.8 54 3.5 0.0 3.5 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 CBK22374.2 - 7.3 6.2 9.3 14 5.3 6.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF329) PH_3 PF14593.1 CBK22376.2 - 3.6e-22 78.1 0.2 4.8e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 PH domain FERM_C PF09380.5 CBK22376.2 - 0.098 12.8 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 FERM C-terminal PH-like domain Arf PF00025.16 CBK22377.2 - 2.7e-27 95.1 0.0 3.2e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBK22377.2 - 2.8e-09 37.5 0.0 3.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBK22377.2 - 1.6e-07 30.8 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CBK22377.2 - 3.2e-06 27.0 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK22377.2 - 3.7e-06 26.2 0.0 4.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBK22377.2 - 0.00011 21.0 1.0 0.011 14.4 0.6 2.0 1 1 1 2 2 2 1 G-protein alpha subunit cobW PF02492.14 CBK22377.2 - 0.0005 19.5 0.1 0.0029 17.0 0.1 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBK22377.2 - 0.0012 19.0 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.13 CBK22377.2 - 0.0029 16.8 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 CBK22377.2 - 0.013 15.1 0.0 0.047 13.3 0.0 1.8 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CBK22377.2 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 1 1 2 2 2 0 NTPase DUF258 PF03193.11 CBK22377.2 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CBK22377.2 - 0.018 14.9 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBK22377.2 - 0.022 15.0 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBK22377.2 - 0.028 15.2 0.1 0.055 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBK22377.2 - 0.029 14.5 0.0 0.091 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 CBK22377.2 - 0.034 14.3 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CBK22377.2 - 0.05 12.9 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase PEPCK_ATP PF01293.15 CBK22377.2 - 0.073 11.5 0.1 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_10 PF12846.2 CBK22377.2 - 0.09 12.1 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 CBK22377.2 - 0.094 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin SRP54 PF00448.17 CBK22377.2 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4379 PF14311.1 CBK22378.2 - 2e-44 149.1 28.4 1.1e-18 66.7 5.0 4.2 4 0 0 4 4 4 4 Domain of unknown function (DUF4379) Cytochrome_C7 PF14522.1 CBK22378.2 - 1.8 8.2 12.2 4.9 6.8 0.8 3.3 3 0 0 3 3 3 0 Cytochrome c7 DnaJ_CXXCXGXG PF00684.14 CBK22378.2 - 9.5 6.3 9.9 3.2 7.8 0.1 3.3 3 0 0 3 3 3 0 DnaJ central domain V-ATPase_C PF03223.10 CBK22379.2 - 4.1e-77 259.5 0.6 5.2e-77 259.2 0.4 1.1 1 0 0 1 1 1 1 V-ATPase subunit C DHHA2 PF02833.9 CBK22380.2 - 1.1e-08 35.3 0.0 1.1e-08 35.3 0.0 2.3 3 0 0 3 3 3 1 DHHA2 domain Methyltransf_23 PF13489.1 CBK22381.2 - 5.1e-24 84.8 0.0 7.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK22381.2 - 3.4e-21 75.4 0.1 9.2e-21 74.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK22381.2 - 2e-15 57.0 0.0 4.8e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK22381.2 - 1.6e-13 50.9 0.0 5e-13 49.3 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22381.2 - 1.6e-13 51.1 0.0 2.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBK22381.2 - 2.4e-10 39.6 0.0 3.9e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CBK22381.2 - 4.9e-09 35.7 0.0 7.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBK22381.2 - 2e-08 34.4 0.0 1.4e-07 31.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK22381.2 - 5.2e-07 29.6 0.0 1e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBK22381.2 - 2.1e-06 27.0 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CBK22381.2 - 2.1e-05 23.7 0.0 4.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CBK22381.2 - 4.6e-05 23.1 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CBK22381.2 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 CBK22381.2 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 CBK22381.2 - 0.0018 17.4 0.0 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 CBK22381.2 - 0.0035 16.4 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 CBK22381.2 - 0.0055 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 CBK22381.2 - 0.0091 15.0 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 CBK22381.2 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.7 CBK22381.2 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.7 CBK22381.2 - 0.029 13.2 0.0 0.057 12.2 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.8 CBK22381.2 - 0.066 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 CBK22381.2 - 0.083 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4050 PF13259.1 CBK22382.2 - 0.0034 17.2 2.8 0.0046 16.8 0.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) DUF3552 PF12072.3 CBK22383.2 - 0.049 12.8 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) A_deaminase_N PF08451.6 CBK22383.2 - 0.098 12.6 1.3 0.86 9.6 0.9 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal RELT PF12606.3 CBK22383.2 - 0.91 8.7 6.1 2 7.5 4.2 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Ufm1 PF03671.9 CBK22384.2 - 6.1e-31 105.9 0.0 1.1e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Acyltransferase PF01553.16 CBK22384.2 - 9.1e-13 47.7 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Glycos_transf_2 PF00535.21 CBK22385.2 - 0.031 13.9 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_C1 PF00112.18 CBK22386.2 - 3.9e-11 43.2 0.1 9.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK22386.2 - 0.0015 18.7 1.9 0.0023 18.1 0.5 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.18 CBK22387.2 - 1.3e-11 44.8 0.1 3.2e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK22387.2 - 0.0021 18.2 0.9 0.0021 18.2 0.6 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) AMP-binding PF00501.23 CBK22388.2 - 0.00062 18.2 0.0 0.00076 17.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FtsJ PF01728.14 CBK22389.2 - 4.1e-56 189.8 0.3 1.1e-55 188.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.7 CBK22389.2 - 3.3e-42 144.4 21.9 3.3e-42 144.4 15.2 4.6 3 3 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 CBK22389.2 - 1.8e-32 112.0 10.5 1.8e-32 112.0 7.3 4.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) Collagen PF01391.13 CBK22389.2 - 1.5 8.4 9.2 0.45 10.1 1.5 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) GCV_T PF01571.16 CBK22390.2 - 8.7e-63 211.4 0.0 1.2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBK22390.2 - 5.1e-25 87.3 0.5 1.2e-24 86.1 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBK22390.2 - 0.044 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Yip1 PF04893.12 CBK22391.2 - 2.1e-08 33.8 16.0 2.8e-08 33.4 9.9 1.8 1 1 1 2 2 2 1 Yip1 domain Ipi1_N PF12333.3 CBK22393.2 - 5.8e-11 42.2 0.7 2.8e-09 36.8 0.2 3.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 CBK22393.2 - 8.9e-05 22.4 4.8 0.044 13.6 0.2 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 BPL_LplA_LipB PF03099.14 CBK22396.2 - 9.3e-15 54.7 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HpaB_N PF11794.3 CBK22396.2 - 0.044 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1765 PF08578.5 CBK22397.2 - 7.6e-12 45.3 6.4 1.1e-11 44.9 1.7 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) RCC1 PF00415.13 CBK22398.2 - 2.5e-26 91.6 9.4 1.8e-09 37.6 0.0 4.3 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK22398.2 - 9.9e-17 60.0 6.2 8.3e-05 22.0 0.0 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat API5 PF05918.6 CBK22399.2 - 2 6.8 6.0 3.5 5.9 4.2 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) 2Fe-2S_thioredx PF01257.14 CBK22400.2 - 4.6e-59 198.1 1.0 6.1e-59 197.7 0.7 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Hexokinase_2 PF03727.11 CBK22401.2 - 1.1e-58 198.3 0.0 1.5e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CBK22401.2 - 5.1e-38 130.4 0.0 6.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase RmlD_sub_bind PF04321.12 CBK22403.2 - 0.00096 18.1 0.0 0.00097 18.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Glutaredoxin PF00462.19 CBK22404.2 - 5.9e-18 64.6 0.0 2.9e-17 62.4 0.0 2.1 3 0 0 3 3 3 1 Glutaredoxin DUF4502 PF14950.1 CBK22404.2 - 0.033 13.3 0.1 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) eIF3g PF12353.3 CBK22405.2 - 8.3e-14 51.6 0.2 1.5e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CBK22405.2 - 6.4e-09 35.3 0.0 1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK22405.2 - 2.9e-08 33.5 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22405.2 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha_L_fucos PF01120.12 CBK22406.2 - 9.3e-28 97.1 0.3 3.6e-27 95.1 0.2 1.9 1 1 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 CBK22406.2 - 0.00082 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Toxin_32 PF08120.6 CBK22406.2 - 0.18 11.4 1.6 0.36 10.4 1.1 1.5 1 0 0 1 1 1 0 Tamulustoxin family LRR_5 PF13306.1 CBK22407.2 - 0.00026 20.6 1.0 0.00045 19.9 0.7 1.3 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) hSac2 PF12456.3 CBK22407.2 - 0.014 14.8 0.7 2.3 7.6 0.0 3.5 2 1 2 4 4 4 0 Inositol phosphatase LRR_8 PF13855.1 CBK22407.2 - 0.18 11.5 4.4 6.2 6.6 0.1 3.3 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CBK22407.2 - 1.3 8.7 5.0 9 6.0 0.9 3.2 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) MORN_2 PF07661.8 CBK22407.2 - 3 8.1 7.9 7.7 6.8 0.5 3.5 3 0 0 3 3 3 0 MORN repeat variant RNA_pol_Rpc4 PF05132.9 CBK22408.2 - 1.2e-15 57.5 0.1 3e-15 56.3 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase III RPC4 Suf PF05843.9 CBK22409.2 - 6.5e-15 55.6 12.9 0.00014 21.7 0.2 5.4 4 1 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CBK22409.2 - 1.9e-10 40.3 6.4 0.76 10.5 0.0 10.4 9 2 2 11 11 10 1 Tetratricopeptide repeat NRDE-2 PF08424.5 CBK22409.2 - 7.5e-10 38.1 10.9 0.00034 19.6 1.6 5.6 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 CBK22409.2 - 5.6e-09 35.4 3.1 0.4 9.6 0.2 5.7 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK22409.2 - 4.1e-08 33.4 0.0 0.97 9.8 0.0 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK22409.2 - 1e-06 28.2 3.8 1.9 8.1 0.0 6.2 7 0 0 7 7 6 2 TPR repeat TPR_16 PF13432.1 CBK22409.2 - 3.6e-05 24.2 12.0 6 7.6 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBK22409.2 - 0.00014 21.6 8.2 5.5 6.7 0.0 6.5 5 1 2 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 CBK22409.2 - 0.00015 21.6 4.4 3.1 7.8 0.0 5.6 6 1 0 6 6 5 1 Tetratricopeptide repeat HAT PF02184.11 CBK22409.2 - 0.00084 19.0 6.3 3.5 7.4 0.0 5.8 6 0 0 6 6 6 1 HAT (Half-A-TPR) repeat TPR_2 PF07719.12 CBK22409.2 - 0.0011 18.7 18.0 0.016 15.1 0.0 8.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK22409.2 - 0.0037 16.9 1.0 4 7.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK22409.2 - 0.014 15.1 7.1 2.5 8.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBK22409.2 - 0.06 13.5 0.6 16 5.9 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK22409.2 - 1.5 9.4 6.9 72 4.1 0.0 5.6 7 0 0 7 7 4 0 Tetratricopeptide repeat Big_5 PF13205.1 CBK22410.2 - 5.9e-05 23.6 1.5 0.19 12.3 0.0 3.2 2 2 1 3 3 3 2 Bacterial Ig-like domain DENN PF02141.16 CBK22411.2 - 1.8e-19 70.1 3.8 3.2e-19 69.3 1.7 2.1 2 1 0 2 2 2 1 DENN (AEX-3) domain Cyclin_N PF00134.18 CBK22413.2 - 6.2e-13 48.4 0.1 8.9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 CBK22414.2 - 2.6e-13 49.4 7.8 1.2e-12 47.2 5.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK22414.2 - 0.021 13.4 0.3 0.021 13.4 0.2 2.0 2 1 1 3 3 3 0 Sugar (and other) transporter Sec23_helical PF04815.10 CBK22414.2 - 6.4 6.2 6.8 11 5.4 0.6 2.7 3 0 0 3 3 3 0 Sec23/Sec24 helical domain zf-C2H2 PF00096.21 CBK22415.2 - 3.3e-07 30.2 32.0 0.0033 17.6 0.4 5.8 5 2 1 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK22415.2 - 0.0023 18.1 33.3 0.0052 17.0 0.6 6.0 6 1 0 6 6 6 3 C2H2-type zinc finger Syntaxin PF00804.20 CBK22415.2 - 0.0081 16.3 0.8 0.019 15.1 0.6 1.5 1 0 0 1 1 1 1 Syntaxin zf-Di19 PF05605.7 CBK22415.2 - 0.03 14.4 1.4 0.03 14.4 1.0 3.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBK22415.2 - 0.044 13.9 0.3 0.044 13.9 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBK22415.2 - 0.051 13.7 0.7 0.051 13.7 0.5 4.5 3 1 0 3 3 3 0 Zinc-finger of C2H2 type HLH PF00010.21 CBK22416.2 - 3e-08 33.2 1.5 6.9e-08 32.0 1.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4656 PF15551.1 CBK22416.2 - 0.001 18.3 0.2 0.001 18.3 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4656) PAS PF00989.19 CBK22416.2 - 0.003 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold MTBP_C PF14920.1 CBK22416.2 - 0.0052 16.3 2.4 0.0082 15.6 1.7 1.2 1 0 0 1 1 1 1 MDM2-binding PAS_8 PF13188.1 CBK22416.2 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 CBK22416.2 - 0.047 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.5 CBK22416.2 - 0.074 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pox_A11 PF05061.8 CBK22416.2 - 0.081 11.9 2.1 0.11 11.5 1.4 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein COPIIcoated_ERV PF07970.7 CBK22417.2 - 1.4e-40 139.2 0.0 1.7e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Baseplate_J PF04865.9 CBK22418.2 - 0.0079 15.5 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Baseplate J-like protein WaaY PF06176.6 CBK22418.2 - 0.024 13.8 0.4 0.25 10.5 0.0 2.0 1 1 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) VASP_tetra PF08776.6 CBK22418.2 - 0.63 9.3 7.2 3.9 6.8 0.6 3.2 4 0 0 4 4 4 0 VASP tetramerisation domain Syntaxin-6_N PF09177.6 CBK22419.2 - 0.012 16.0 0.7 0.046 14.1 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Pox_G5 PF04599.7 CBK22419.2 - 0.014 14.0 2.0 0.02 13.6 1.4 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein DUF842 PF05811.8 CBK22419.2 - 0.055 12.9 2.3 0.42 10.0 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) GAS PF13851.1 CBK22419.2 - 0.069 12.3 3.6 0.042 13.0 0.6 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ferritin PF00210.19 CBK22419.2 - 0.088 12.5 1.0 0.29 10.8 0.4 2.0 1 1 0 1 1 1 0 Ferritin-like domain Bac_surface_Ag PF01103.18 CBK22420.2 - 7.6e-05 22.3 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Surface antigen TIM PF00121.13 CBK22421.2 - 6e-84 280.9 0.2 6e-84 280.9 0.1 1.5 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_C PF02800.15 CBK22421.2 - 1.7e-69 232.3 0.0 5.9e-69 230.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBK22421.2 - 5.8e-56 188.6 0.1 1.4e-55 187.3 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.9 CBK22421.2 - 0.035 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family GIDA PF01134.17 CBK22422.2 - 6.9e-136 453.1 0.0 9.7e-136 452.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CBK22422.2 - 3.1e-12 46.3 0.0 7.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 CBK22422.2 - 6.3e-11 41.9 0.5 1.9e-09 37.1 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBK22422.2 - 1.3e-09 38.1 0.4 4.2e-09 36.5 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBK22422.2 - 7.2e-07 28.4 0.9 0.022 13.6 0.7 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBK22422.2 - 3e-05 23.0 3.0 4.9e-05 22.3 1.7 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CBK22422.2 - 0.00029 21.1 0.4 0.00093 19.5 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CBK22422.2 - 0.0021 17.6 0.3 0.0045 16.5 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 CBK22422.2 - 0.0026 17.8 0.9 0.059 13.4 0.6 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBK22422.2 - 0.0029 16.7 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CBK22422.2 - 0.012 14.0 2.6 0.024 13.1 1.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 CBK22422.2 - 0.12 11.3 0.7 0.2 10.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain DBR1 PF05011.8 CBK22422.2 - 0.14 12.0 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Lycopene_cycl PF05834.7 CBK22422.2 - 0.19 10.5 0.9 1.2 8.0 0.5 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein DUF1012 PF06241.7 CBK22423.2 - 0.013 15.1 0.2 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1012) Stc1 PF12898.2 CBK22423.2 - 0.032 14.2 6.1 0.052 13.5 4.2 1.3 1 0 0 1 1 1 0 Stc1 domain DnaJ PF00226.26 CBK22424.2 - 0.13 11.9 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 DnaJ domain Pkinase PF00069.20 CBK22425.2 - 5.7e-34 117.4 0.0 7e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22425.2 - 2.8e-14 52.8 0.0 3.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK22425.2 - 0.00062 19.5 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBK22425.2 - 0.022 13.5 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EGF_2 PF07974.8 CBK22426.2 - 7e-30 102.8 127.4 6.8e-05 22.9 3.7 9.6 9 0 0 9 9 9 9 EGF-like domain EGF PF00008.22 CBK22426.2 - 3.4e-08 33.2 92.1 0.00045 20.1 1.7 8.7 8 0 0 8 8 8 6 EGF-like domain zf-RanBP PF00641.13 CBK22426.2 - 3.1e-07 29.3 3.4 1.7e-06 27.0 2.3 2.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DSL PF01414.14 CBK22426.2 - 0.0017 18.2 17.1 0.0017 18.2 11.8 7.4 1 1 7 8 8 8 1 Delta serrate ligand DnaJ PF00226.26 CBK22427.2 - 4.5e-09 35.9 0.0 7.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBK22427.2 - 3e-06 27.0 0.0 4.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF1891 PF09004.5 CBK22427.2 - 0.061 12.7 1.1 4.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) XPG_I PF00867.13 CBK22429.2 - 6.1e-22 77.4 0.1 1.7e-21 76.0 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBK22429.2 - 9.2e-06 25.8 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CBK22429.2 - 0.089 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 XPG domain containing Reo_sigmaC PF04582.7 CBK22430.2 - 0.0014 17.9 0.6 0.0019 17.4 0.4 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1110 PF06533.7 CBK22430.2 - 0.02 14.6 0.3 0.037 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) ORF6C PF10552.4 CBK22430.2 - 0.076 12.7 11.9 0.21 11.3 0.8 2.6 2 1 0 2 2 2 0 ORF6C domain Laminin_II PF06009.7 CBK22430.2 - 0.077 12.7 13.2 0.73 9.5 1.8 2.4 1 1 1 2 2 2 0 Laminin Domain II M PF02370.11 CBK22430.2 - 0.082 13.2 2.5 0.082 13.2 1.7 5.0 4 1 0 4 4 4 0 M protein repeat NPV_P10 PF05531.7 CBK22430.2 - 0.2 11.9 3.8 13 6.1 2.6 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IFP_35_N PF07334.8 CBK22430.2 - 0.23 11.4 14.5 1.8 8.6 0.3 3.7 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Tnp_P_element PF12017.3 CBK22430.2 - 0.35 10.0 9.5 0.36 10.0 2.1 2.2 1 1 1 2 2 2 0 Transposase protein Bacillus_HBL PF05791.6 CBK22430.2 - 0.4 10.0 13.8 0.018 14.4 3.0 2.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Ax_dynein_light PF10211.4 CBK22430.2 - 0.52 10.1 21.4 3.9 7.2 6.5 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain AAA_13 PF13166.1 CBK22430.2 - 0.59 8.5 17.4 1.2 7.4 11.9 1.6 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 CBK22430.2 - 0.94 8.6 10.8 1.1 8.3 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.3 CBK22430.2 - 0.94 8.0 11.1 1.9 7.0 6.8 1.7 1 1 1 2 2 2 0 Aluminium activated malate transporter DUF4407 PF14362.1 CBK22430.2 - 1.1 8.0 8.5 16 4.3 5.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.8 CBK22430.2 - 1.2 8.5 13.9 0.83 9.0 5.6 2.4 1 1 1 2 2 2 0 fzo-like conserved region Transposase_22 PF02994.9 CBK22430.2 - 1.2 7.5 24.2 0.33 9.4 2.7 2.2 1 1 1 2 2 2 0 L1 transposable element Seryl_tRNA_N PF02403.17 CBK22430.2 - 1.9 8.5 21.7 4.1 7.4 6.9 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 CBK22430.2 - 1.9 8.8 21.2 3.2 8.1 5.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 CBK22430.2 - 2.5 5.8 14.0 2.9 5.6 9.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 CBK22430.2 - 3 5.9 18.1 3.5 5.8 12.5 1.3 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CBK22430.2 - 3.5 7.1 33.4 0.4 10.2 18.5 2.1 1 1 1 2 2 2 0 IncA protein DUF730 PF05325.6 CBK22430.2 - 3.7 7.3 7.0 1.8 8.3 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF730) DUF1192 PF06698.6 CBK22430.2 - 4.2 7.2 10.2 4.4 7.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) GvpK PF05121.7 CBK22430.2 - 4.3 7.2 11.9 0.31 10.8 1.7 2.8 2 2 0 2 2 2 0 Gas vesicle protein K RNA_pol_Rpb1_2 PF00623.15 CBK22430.2 - 4.5 7.1 6.4 2.9 7.7 1.8 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 2 5_nucleotid PF05761.9 CBK22430.2 - 5.5 5.3 14.0 50 2.2 9.7 1.9 1 1 0 1 1 1 0 5' nucleotidase family DUF1664 PF07889.7 CBK22430.2 - 5.7 6.7 13.2 7.5 6.3 5.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.6 CBK22430.2 - 5.9 6.7 6.7 1.5 8.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) SlyX PF04102.7 CBK22430.2 - 6 7.3 15.3 3.4 8.1 1.4 2.8 2 1 1 3 3 2 0 SlyX DivIC PF04977.10 CBK22430.2 - 6.4 6.3 15.6 0.84 9.1 1.5 2.9 1 1 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 CBK22430.2 - 6.4 5.3 24.8 17 3.9 17.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 CBK22430.2 - 6.5 6.6 17.5 3.6 7.5 5.7 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GreA_GreB_N PF03449.10 CBK22430.2 - 7.7 6.6 15.5 31 4.7 6.2 3.7 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal DUF4140 PF13600.1 CBK22430.2 - 9.3 6.7 9.9 49 4.4 1.2 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 CBK22430.2 - 9.9 6.0 30.9 6.5 6.6 10.4 2.3 1 1 2 3 3 3 0 Tropomyosin like DUF4005 PF13178.1 CBK22432.2 - 0.043 14.0 6.7 0.13 12.5 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) IF4E PF01652.13 CBK22433.2 - 6.9e-44 149.2 1.2 8e-44 149.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FAD_binding_2 PF00890.19 CBK22434.2 - 2e-121 405.7 3.2 2.7e-121 405.3 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBK22434.2 - 7.7e-48 161.5 1.8 1.1e-47 161.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBK22434.2 - 1.2e-06 27.7 0.1 8.6e-06 24.8 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBK22434.2 - 1.4e-06 27.6 0.2 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CBK22434.2 - 2.6e-05 24.2 1.4 0.00034 20.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBK22434.2 - 4.5e-05 22.4 0.9 0.0025 16.7 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CBK22434.2 - 0.00027 20.1 0.2 0.00045 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CBK22434.2 - 0.017 15.4 0.0 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 CBK22434.2 - 0.022 13.2 1.5 0.038 12.4 0.2 2.0 3 0 0 3 3 3 0 HI0933-like protein Ribosomal_L13 PF00572.13 CBK22435.2 - 6.7e-22 77.9 0.1 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 PRP21_like_P PF12230.3 CBK22437.2 - 7.6e-20 71.3 7.3 1.2e-18 67.4 5.0 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CBK22437.2 - 0.0037 16.8 0.1 0.034 13.8 0.1 2.2 1 1 0 1 1 1 1 Surp module MBOAT PF03062.14 CBK22438.2 - 2e-28 99.4 18.9 2e-28 99.4 13.1 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family FANCI_S2 PF14676.1 CBK22438.2 - 0.099 12.5 0.5 0.31 10.9 0.1 1.9 2 1 0 2 2 2 0 FANCI solenoid 2 ATP_bind_1 PF03029.12 CBK22439.2 - 1.3e-76 257.3 0.4 1.7e-76 256.9 0.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CBK22439.2 - 8.2e-09 35.3 0.1 5e-08 32.7 0.1 1.9 1 1 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 CBK22439.2 - 2.9e-06 26.8 0.0 0.0043 16.5 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK22439.2 - 6.6e-06 26.0 0.1 1.7e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CBK22439.2 - 2.4e-05 25.1 0.0 4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 CBK22439.2 - 6.8e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 CBK22439.2 - 8.6e-05 21.8 0.3 0.0073 15.5 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.17 CBK22439.2 - 0.00011 21.7 0.2 0.00035 20.0 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CBK22439.2 - 0.00058 19.0 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CBK22439.2 - 0.00059 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 CBK22439.2 - 0.00061 18.7 0.0 0.0013 17.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.9 CBK22439.2 - 0.00073 19.2 0.1 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CBK22439.2 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK22439.2 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CBK22439.2 - 0.0018 17.9 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 CBK22439.2 - 0.0024 16.6 0.0 0.035 12.9 0.0 2.1 2 0 0 2 2 2 1 ArgK protein PduV-EutP PF10662.4 CBK22439.2 - 0.0031 16.9 0.2 0.068 12.6 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CBK22439.2 - 0.0048 16.1 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 CBK22439.2 - 0.0049 16.3 0.3 0.042 13.2 0.0 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBK22439.2 - 0.0058 15.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CBK22439.2 - 0.01 15.2 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Ras family Arch_ATPase PF01637.13 CBK22439.2 - 0.011 15.4 0.1 0.018 14.7 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase 6PF2K PF01591.13 CBK22439.2 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_18 PF13238.1 CBK22439.2 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CBK22439.2 - 0.017 14.1 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.13 CBK22439.2 - 0.018 14.6 0.0 0.037 13.5 0.0 1.5 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBK22439.2 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 CBK22439.2 - 0.018 15.2 0.1 0.24 11.5 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBK22439.2 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CBK22439.2 - 0.021 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CBK22439.2 - 0.034 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CBK22439.2 - 0.034 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 CBK22439.2 - 0.052 13.2 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 CBK22439.2 - 0.08 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 CBK22439.2 - 0.094 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase T2SE PF00437.15 CBK22439.2 - 0.097 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CBK22439.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 CBK22439.2 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 CBK22439.2 - 0.1 12.0 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.12 CBK22439.2 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 1 0 Thymidylate kinase G-alpha PF00503.15 CBK22439.2 - 0.11 11.1 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Thioredoxin_7 PF13899.1 CBK22439.2 - 0.12 12.4 0.1 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like KTI12 PF08433.5 CBK22439.2 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 CBK22439.2 - 0.14 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CBK22439.2 - 0.14 11.3 0.1 1.1 8.4 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBK22439.2 - 0.16 11.7 0.3 1.7 8.4 0.2 2.1 1 1 0 1 1 1 0 Dynamin family BCIP PF13862.1 CBK22440.2 - 1.2e-36 126.1 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Ribosomal_60s PF00428.14 CBK22441.2 - 1.5e-23 83.0 17.5 1.7e-23 82.8 12.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein BUD22 PF09073.5 CBK22441.2 - 0.041 12.9 2.2 0.045 12.8 1.5 1.1 1 0 0 1 1 1 0 BUD22 DUF867 PF05908.6 CBK22441.2 - 0.055 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Myc_N PF01056.13 CBK22441.2 - 0.063 12.4 3.4 0.06 12.5 2.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.7 CBK22441.2 - 0.21 11.4 4.4 0.25 11.1 3.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.8 CBK22441.2 - 1.2 8.6 8.0 1.5 8.4 5.4 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.6 CBK22441.2 - 2.5 7.3 11.4 2.8 7.1 7.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_L18e PF00828.14 CBK22442.2 - 4.3e-24 85.3 0.0 6.5e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 OprF PF05736.6 CBK22442.2 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Ribosomal_S17e PF00833.13 CBK22443.2 - 2.1e-52 176.0 0.9 2.9e-52 175.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal S17 ParA PF10609.4 CBK22444.2 - 5.5e-30 103.0 0.0 1.3e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBK22444.2 - 1.1e-16 60.8 0.0 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBK22444.2 - 7.9e-11 42.1 0.0 1.9e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 CBK22444.2 - 3.4e-07 29.6 0.0 5.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ DUF59 PF01883.14 CBK22444.2 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Fer4_NifH PF00142.13 CBK22444.2 - 0.00035 19.8 0.0 0.0014 17.8 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 CBK22444.2 - 0.00092 18.3 5.6 0.041 12.9 0.5 3.7 3 2 1 4 4 4 1 Anion-transporting ATPase YhjQ PF06564.7 CBK22444.2 - 0.0012 18.2 0.6 0.005 16.2 0.4 1.9 1 1 0 1 1 1 1 YhjQ protein VirC1 PF07015.6 CBK22444.2 - 0.039 13.0 0.2 0.1 11.6 0.1 1.7 1 1 1 2 2 2 0 VirC1 protein Cas_Csd1 PF09709.5 CBK22446.2 - 0.037 12.3 0.4 0.047 11.9 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DUF310 PF03750.8 CBK22446.2 - 0.087 13.0 0.2 0.093 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF310) AA_synth PF06684.6 CBK22446.2 - 0.09 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Amino acid synthesis Y_phosphatase3 PF13350.1 CBK22447.2 - 0.00013 22.3 0.0 0.00019 21.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 CBK22447.2 - 0.00015 21.2 0.1 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 CBK22447.2 - 0.00058 19.2 0.1 0.00082 18.7 0.1 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBK22447.2 - 0.0094 15.5 0.1 0.026 14.1 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBK22447.2 - 0.013 15.5 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ion_trans PF00520.26 CBK22447.2 - 0.044 13.0 2.7 0.3 10.3 1.4 2.0 2 0 0 2 2 2 0 Ion transport protein Y_phosphatase2 PF03162.8 CBK22447.2 - 0.1 11.9 0.3 0.26 10.6 0.2 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.4 CBK22448.2 - 2.7e-06 27.1 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Ribosomal_L29 PF00831.18 CBK22449.2 - 3.7e-12 45.7 0.4 3.7e-12 45.7 0.3 2.2 1 1 1 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CBK22449.2 - 0.00043 20.5 5.6 0.00063 19.9 3.9 1.3 1 1 0 1 1 1 1 Ribosomal protein S9/S16 DUF382 PF04037.8 CBK22449.2 - 0.0019 18.0 1.0 0.0024 17.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF382) Rogdi_lz PF10259.4 CBK22449.2 - 0.0038 16.3 0.0 0.0044 16.1 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein CHASE3 PF05227.8 CBK22449.2 - 0.015 14.9 5.5 0.017 14.8 3.8 1.0 1 0 0 1 1 1 0 CHASE3 domain RhaA PF06134.6 CBK22449.2 - 0.1 11.4 0.2 0.16 10.8 0.1 1.4 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) PP2C PF00481.16 CBK22450.2 - 3.6e-35 121.5 0.0 5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBK22450.2 - 2.1e-06 27.2 0.0 6.6e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PEPCK_ATP PF01293.15 CBK22451.2 - 0.00014 20.5 0.0 0.00022 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Syncollin PF15138.1 CBK22451.2 - 0.068 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Syncollin Sugar_tr PF00083.19 CBK22452.2 - 0.00069 18.3 9.3 0.00078 18.1 6.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter EamA PF00892.15 CBK22452.2 - 0.59 10.1 6.0 1.2 9.1 4.2 1.6 1 1 0 1 1 1 0 EamA-like transporter family 2-Hacid_dh_C PF02826.14 CBK22453.2 - 2.9e-62 208.9 0.0 3.9e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBK22453.2 - 3.3e-28 97.8 0.0 4.1e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 CBK22453.2 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 CBK22453.2 - 0.0009 19.1 0.0 0.0021 17.9 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CBK22453.2 - 0.026 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NmrA PF05368.8 CBK22453.2 - 0.07 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Hydrolase_6 PF13344.1 CBK22454.2 - 1.5e-30 105.0 0.0 2.3e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBK22454.2 - 9.6e-14 50.8 0.0 3.8e-13 48.9 0.0 2.0 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 CBK22454.2 - 8e-10 39.4 0.0 1e-09 39.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK22454.2 - 8.7e-05 22.8 0.1 0.1 12.7 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CBK22454.2 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 CBK22454.2 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase LAGLIDADG_3 PF14528.1 CBK22454.2 - 0.13 12.4 0.3 0.86 9.8 0.1 2.2 2 1 0 2 2 2 0 LAGLIDADG-like domain MRP-L27 PF09809.4 CBK22456.2 - 9.1e-18 63.9 0.2 1e-17 63.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 F-actin_cap_A PF01267.12 CBK22457.2 - 3.1e-31 108.4 0.0 3.6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Tim17 PF02466.14 CBK22458.2 - 8.6e-14 51.6 3.1 1.1e-13 51.3 2.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 CBK22458.2 - 0.56 10.3 5.7 14 5.9 0.0 2.7 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DnaJ_CXXCXGXG PF00684.14 CBK22459.2 - 6.4e-05 22.9 5.9 6.4e-05 22.9 4.1 2.9 3 0 0 3 3 3 1 DnaJ central domain zinc-ribbons_6 PF07191.7 CBK22459.2 - 0.047 13.4 4.5 0.56 10.0 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbons zf-Di19 PF05605.7 CBK22459.2 - 0.086 12.9 12.7 2 8.5 0.0 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding MRP-S26 PF14943.1 CBK22460.2 - 0.00049 19.6 2.0 0.00049 19.6 1.4 2.7 3 0 0 3 3 3 1 Mitochondrial ribosome subunit S26 TMCO5 PF14992.1 CBK22460.2 - 0.0071 15.5 10.2 0.0071 15.5 7.1 2.8 3 0 0 3 3 3 1 TMCO5 family PBC PF03792.8 CBK22460.2 - 0.22 11.1 12.2 0.045 13.4 2.2 3.0 3 0 0 3 3 3 0 PBC domain DUF4407 PF14362.1 CBK22460.2 - 0.38 9.6 10.5 0.35 9.7 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 CBK22460.2 - 1.7 8.5 16.7 0.19 11.6 0.6 4.3 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) TSC22 PF01166.13 CBK22460.2 - 3.7 7.5 16.5 1.5 8.8 0.2 4.1 3 1 1 4 4 4 0 TSC-22/dip/bun family Filament PF00038.16 CBK22460.2 - 9.4 5.5 32.7 4.1 6.7 10.0 3.5 2 2 0 2 2 2 0 Intermediate filament protein Shugoshin_N PF07558.6 CBK22460.2 - 9.4 6.0 8.6 6 6.6 0.2 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region F_actin_bind PF08919.5 CBK22462.2 - 0.013 15.2 0.1 0.083 12.6 0.0 2.3 2 0 0 2 2 2 0 F-actin binding POR_N PF01855.14 CBK22463.2 - 1.5e-45 155.5 0.0 2.7e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK22463.2 - 5.5e-26 91.5 0.3 1.2e-25 90.4 0.2 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 CBK22463.2 - 6.9e-11 41.5 0.0 1.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_16 PF13484.1 CBK22463.2 - 2.4e-09 37.8 5.7 0.0005 20.7 0.8 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.2 CBK22463.2 - 2.8e-09 37.2 6.5 2.8e-09 37.2 4.5 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 CBK22463.2 - 1.6e-08 34.2 0.2 4.6e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK22463.2 - 3.7e-08 32.6 18.7 1.3e-05 24.5 0.9 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.1 CBK22463.2 - 4.1e-07 30.1 9.9 0.0017 18.5 1.0 2.9 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK22463.2 - 6.5e-06 25.8 13.5 3.5e-05 23.4 8.2 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK22463.2 - 1.5e-05 24.8 11.2 0.0003 20.7 8.1 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.1 CBK22463.2 - 1.8e-05 24.5 14.0 0.0012 18.7 9.9 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK22463.2 - 2.7e-05 23.8 19.2 0.0002 21.0 2.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_15 PF13459.1 CBK22463.2 - 0.0004 20.8 4.2 0.52 10.9 0.5 2.9 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_17 PF13534.1 CBK22463.2 - 0.0006 20.1 11.4 0.0023 18.2 6.8 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 CBK22463.2 - 0.0022 18.3 6.4 0.13 12.6 0.8 3.1 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_18 PF13746.1 CBK22463.2 - 0.0026 18.1 12.2 0.51 10.8 0.1 3.7 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK22463.2 - 0.004 17.3 19.8 0.0093 16.2 1.3 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 CBK22463.2 - 0.0044 16.8 2.7 0.0044 16.8 1.9 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Transketolase_C PF02780.15 CBK22463.2 - 0.016 15.1 0.0 0.053 13.4 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain BrkDBD PF09607.5 CBK22463.2 - 0.11 12.0 0.3 0.8 9.3 0.1 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain Brix PF04427.13 CBK22464.2 - 2.4e-38 131.7 1.0 4.8e-38 130.7 0.7 1.5 1 0 0 1 1 1 1 Brix domain Fe-ADH PF00465.14 CBK22465.2 - 1.9e-45 155.0 0.0 2.1e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK22465.2 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Chal_sti_synt_N PF00195.14 CBK22465.2 - 0.059 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DASH_Dad3 PF08656.5 CBK22466.2 - 0.00048 19.7 0.4 0.00059 19.4 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 SlyX PF04102.7 CBK22466.2 - 0.0055 17.0 0.9 0.0077 16.5 0.6 1.4 1 1 0 1 1 1 1 SlyX Prominin PF05478.6 CBK22466.2 - 0.02 12.4 1.1 0.02 12.4 0.8 1.0 1 0 0 1 1 1 0 Prominin Fzo_mitofusin PF04799.8 CBK22466.2 - 0.032 13.6 1.9 0.061 12.7 1.3 1.6 1 1 0 1 1 1 0 fzo-like conserved region DASH_Dad4 PF08650.5 CBK22466.2 - 0.033 14.0 1.1 0.047 13.6 0.8 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad4 TMF_DNA_bd PF12329.3 CBK22466.2 - 0.058 13.1 0.6 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 CBK22466.2 - 0.06 12.5 0.3 0.076 12.2 0.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0118 PF01594.11 CBK22466.2 - 0.062 12.2 0.6 0.071 12.0 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 Laminin_II PF06009.7 CBK22466.2 - 0.083 12.6 1.6 0.15 11.7 1.1 1.6 1 1 0 1 1 1 0 Laminin Domain II Sec2p PF06428.6 CBK22466.2 - 0.083 12.7 0.2 0.095 12.5 0.2 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.6 CBK22466.2 - 0.1 12.2 1.8 0.16 11.6 1.2 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Chordopox_A30L PF06015.7 CBK22466.2 - 0.12 11.9 0.9 0.29 10.7 0.6 1.6 1 1 0 1 1 1 0 Chordopoxvirus A30L protein VBS PF08913.5 CBK22466.2 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Vinculin Binding Site DASH_Hsk3 PF08227.6 CBK22466.2 - 0.17 12.1 1.4 0.77 9.9 1.0 2.0 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like MORN PF02493.15 CBK22467.2 - 2.8e-09 36.1 11.0 3e-06 26.6 0.7 3.5 3 0 0 3 3 3 2 MORN repeat MORN_2 PF07661.8 CBK22468.2 - 4e-08 32.3 19.0 0.086 12.9 0.8 6.9 6 0 0 6 6 6 4 MORN repeat variant MORN PF02493.15 CBK22468.2 - 0.00018 21.0 36.9 0.00026 20.5 0.4 9.2 10 0 0 10 10 10 4 MORN repeat DUF2963 PF11178.3 CBK22468.2 - 0.03 13.7 2.0 8.7 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) Aminotran_5 PF00266.14 CBK22469.2 - 1.6e-35 122.5 0.0 2.2e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBK22469.2 - 0.0037 16.2 0.0 0.02 13.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II WEMBL PF05701.6 CBK22470.2 - 1e-14 53.9 116.8 1.5e-06 27.0 22.0 5.5 1 1 4 5 5 5 4 Weak chloroplast movement under blue light AAA_27 PF13514.1 CBK22470.2 - 4e-09 34.7 95.4 7.9e-05 20.5 26.3 3.3 1 1 1 2 2 2 2 AAA domain Baculo_PEP_C PF04513.7 CBK22470.2 - 1.4e-07 31.4 69.5 0.019 14.8 0.2 7.0 2 1 2 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 CBK22470.2 - 1.5e-06 28.0 75.1 0.022 14.5 3.7 9.3 1 1 7 9 9 9 4 Protein of unknown function (DUF1664) Laminin_II PF06009.7 CBK22470.2 - 1.7e-06 27.8 93.4 0.00018 21.3 2.4 9.6 1 1 8 9 9 9 1 Laminin Domain II CENP-F_leu_zip PF10473.4 CBK22470.2 - 1.1e-05 25.2 99.3 0.09 12.6 4.6 8.8 2 2 4 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 CBK22470.2 - 3.2e-05 21.9 101.9 0.0009 17.1 30.9 4.0 1 1 2 3 3 3 2 Myosin tail DUF869 PF05911.6 CBK22470.2 - 5.3e-05 21.6 94.8 0.046 11.9 21.3 3.3 1 1 2 3 3 3 3 Plant protein of unknown function (DUF869) Tropomyosin PF00261.15 CBK22470.2 - 6.2e-05 22.2 24.2 6.2e-05 22.2 16.8 5.8 1 1 2 4 4 4 1 Tropomyosin DUF3584 PF12128.3 CBK22470.2 - 9.4e-05 19.9 96.1 0.0002 18.8 46.3 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) Syntaxin PF00804.20 CBK22470.2 - 0.00011 22.2 83.9 0.11 12.7 2.8 7.8 3 2 5 8 8 8 4 Syntaxin AAA_13 PF13166.1 CBK22470.2 - 0.00018 20.1 79.2 0.012 14.1 10.9 4.3 1 1 3 4 4 4 4 AAA domain Spc7 PF08317.6 CBK22470.2 - 0.00019 20.2 91.4 0.012 14.3 9.1 6.1 1 1 5 6 6 6 4 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CBK22470.2 - 0.00084 19.0 3.6 0.00084 19.0 2.5 9.9 1 1 8 10 10 9 1 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 CBK22470.2 - 0.002 17.9 63.2 0.1 12.4 1.6 10.2 3 3 7 10 10 10 2 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CBK22470.2 - 0.0031 16.7 86.0 0.15 11.1 8.6 6.2 1 1 4 6 6 6 4 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CBK22470.2 - 0.0042 17.3 67.0 1.1 9.5 0.3 11.1 5 2 4 10 10 10 2 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 CBK22470.2 - 0.0048 16.8 4.0 0.0048 16.8 2.8 7.7 2 1 3 7 7 7 1 Modifier of rudimentary (Mod(r)) protein APG17 PF04108.7 CBK22470.2 - 0.0071 15.1 1.6 0.0071 15.1 1.1 6.4 1 1 2 3 3 3 1 Autophagy protein Apg17 IncA PF04156.9 CBK22470.2 - 0.049 13.2 92.4 0.8 9.2 11.5 6.5 1 1 2 5 5 4 0 IncA protein DUF4294 PF14127.1 CBK22470.2 - 0.11 12.0 0.1 0.11 12.0 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF4294) TPR_MLP1_2 PF07926.7 CBK22470.2 - 0.13 11.9 108.2 0.18 11.5 2.0 9.2 2 1 8 10 10 9 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 CBK22470.2 - 0.21 11.0 96.9 0.086 12.2 6.3 6.4 1 1 3 5 5 5 0 Intermediate filament protein DUF812 PF05667.6 CBK22470.2 - 0.48 8.8 102.8 0.13 10.7 12.7 5.9 1 1 4 5 5 5 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 CBK22470.2 - 0.55 10.3 72.0 0.54 10.3 2.3 7.6 1 1 7 8 8 8 0 Fibrinogen alpha/beta chain family Activin_recp PF01064.18 CBK22470.2 - 0.73 10.5 7.7 0.2 12.2 2.8 2.0 2 0 0 2 2 1 0 Activin types I and II receptor domain B2 PF11473.3 CBK22470.2 - 1.5 8.4 9.5 0.43 10.2 1.4 3.7 3 0 0 3 3 3 0 RNA binding protein B2 Laminin_I PF06008.9 CBK22470.2 - 1.5 8.0 94.5 0.32 10.2 2.4 6.4 1 1 2 4 4 4 0 Laminin Domain I EzrA PF06160.7 CBK22470.2 - 1.9 6.5 77.5 15 3.5 22.5 5.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DASH_Dam1 PF08653.5 CBK22470.2 - 2.5 7.9 18.5 12 5.7 0.1 7.5 7 1 0 8 8 6 0 DASH complex subunit Dam1 HALZ PF02183.13 CBK22470.2 - 2.5 7.8 24.3 3.1 7.5 0.1 7.7 10 0 0 10 10 7 0 Homeobox associated leucine zipper MCPsignal PF00015.16 CBK22470.2 - 3.3 7.1 109.8 0.023 14.2 5.5 7.3 1 1 5 7 7 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2730 PF10805.3 CBK22470.2 - 5.7 6.7 35.5 0.34 10.6 1.4 8.2 4 4 1 7 7 7 0 Protein of unknown function (DUF2730) ALIX_LYPXL_bnd PF13949.1 CBK22470.2 - 9.1 5.1 91.2 1.1 8.1 16.4 4.6 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV DUF1537 PF07005.6 CBK22471.2 - 0.045 13.4 0.4 0.086 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 Pkinase PF00069.20 CBK22472.2 - 7.8e-54 182.5 0.0 9.4e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22472.2 - 7.5e-19 67.7 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK22472.2 - 1.9e-06 27.7 0.0 3e-05 23.8 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBK22472.2 - 0.0019 17.8 0.2 0.0084 15.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.1 CBK22472.2 - 0.019 13.9 0.0 0.044 12.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 CBK22472.2 - 0.032 13.5 0.1 0.82 8.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 CBK22472.2 - 0.071 12.1 0.1 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRP4 PF08799.6 CBK22473.2 - 1.7e-13 49.5 0.3 2.5e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Haemadin PF09065.5 CBK22473.2 - 0.12 11.9 0.3 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Haemadin WD40 PF00400.27 CBK22474.2 - 1.9e-37 125.8 6.1 1.2e-08 34.5 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBK22474.2 - 1.8e-05 23.0 2.3 0.16 10.0 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 CSD PF00313.17 CBK22475.2 - 1.2e-26 92.2 0.1 1.5e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CBK22475.2 - 0.00016 21.0 0.1 0.00027 20.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain MORN PF02493.15 CBK22476.2 - 2.6e-09 36.2 16.0 0.00054 19.5 0.2 5.7 5 0 0 5 5 5 3 MORN repeat LRR_8 PF13855.1 CBK22476.2 - 2.7e-05 23.8 7.8 0.23 11.2 0.3 4.4 2 2 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 CBK22476.2 - 0.02 14.4 0.2 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Pox_I5 PF04713.7 CBK22476.2 - 0.042 13.5 4.7 0.13 12.0 1.7 2.2 2 0 0 2 2 2 0 Poxvirus protein I5 LRR_4 PF12799.2 CBK22476.2 - 0.047 13.3 8.4 1.5 8.5 0.5 5.1 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF1295 PF06966.7 CBK22477.2 - 3.3e-10 39.6 1.6 4.6e-10 39.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CBK22477.2 - 9e-09 35.2 2.8 1.2e-08 34.8 1.9 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CBK22477.2 - 3.5e-08 33.5 2.6 5e-08 33.0 1.2 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 CBK22477.2 - 5.1e-06 26.5 1.4 1.1e-05 25.5 0.9 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 CBK22477.2 - 5.8e-05 21.8 2.8 7.7e-05 21.4 1.9 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UbiA PF01040.13 CBK22477.2 - 0.64 9.1 7.5 1.8 7.7 5.2 1.6 1 1 0 1 1 1 0 UbiA prenyltransferase family Dynamin_N PF00350.18 CBK22478.2 - 2.1e-51 174.0 0.0 3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CBK22478.2 - 1.9e-27 95.8 0.1 2.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 CBK22478.2 - 0.00012 22.0 0.1 0.00041 20.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBK22478.2 - 0.021 15.3 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CBK22478.2 - 0.025 13.8 0.2 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B GED PF02212.13 CBK22479.2 - 1.5e-22 79.2 3.8 3.1e-22 78.2 2.6 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 CBK22479.2 - 5.7e-06 26.4 0.1 1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK22479.2 - 0.0036 17.5 1.6 0.015 15.5 1.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain REV PF00424.13 CBK22479.2 - 0.027 14.3 0.3 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PH_8 PF15409.1 CBK22479.2 - 0.043 13.8 0.2 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 CBK22480.2 - 3.6e-17 62.3 0.0 4.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22480.2 - 1.7e-09 37.1 0.0 2.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B_2 PF03175.8 CBK22481.2 - 2.1e-07 30.0 11.2 0.0011 17.7 7.8 3.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral He_PIG PF05345.7 CBK22482.2 - 2.7e-14 52.8 44.2 1.5e-05 24.9 3.4 5.4 4 1 0 4 4 4 3 Putative Ig domain I-set PF07679.11 CBK22482.2 - 0.00022 21.0 3.1 2.1 8.2 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain TMEM154 PF15102.1 CBK22482.2 - 0.0027 17.4 2.5 0.0027 17.4 1.7 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF912 PF06024.7 CBK22482.2 - 0.0055 16.7 0.9 0.011 15.7 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) F5_F8_type_C PF00754.20 CBK22482.2 - 0.0067 16.2 18.2 0.065 13.0 0.6 4.9 5 1 0 5 5 4 2 F5/8 type C domain EphA2_TM PF14575.1 CBK22482.2 - 0.022 15.1 1.0 0.045 14.1 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CBK22482.2 - 0.023 14.3 3.6 0.055 13.1 2.5 1.5 1 0 0 1 1 1 0 Rifin/stevor family DUF1510 PF07423.6 CBK22482.2 - 0.034 13.5 0.5 0.061 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Baculo_11_kDa PF06143.6 CBK22482.2 - 0.055 12.8 3.2 0.11 11.8 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.1 CBK22482.2 - 0.088 12.9 2.7 0.19 11.8 1.9 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.4 CBK22482.2 - 0.088 12.2 1.7 0.25 10.7 1.2 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1180 PF06679.7 CBK22482.2 - 0.091 12.6 3.0 0.072 12.9 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) OAD_gamma PF04277.8 CBK22482.2 - 0.29 11.5 4.4 0.79 10.1 3.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain P12 PF12669.2 CBK22482.2 - 0.46 10.7 3.8 0.88 9.8 2.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family ASFV_J13L PF05568.6 CBK22482.2 - 6.5 6.2 9.8 1.9 7.9 3.9 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein Fe_hyd_lg_C PF02906.9 CBK22483.2 - 2.9e-57 194.1 0.0 4.4e-51 173.8 0.0 2.3 1 1 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain NAPRTase PF04095.11 CBK22483.2 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family MFS_1 PF07690.11 CBK22484.2 - 1.7e-29 102.6 50.7 9e-26 90.4 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Guanylate_kin PF00625.16 CBK22485.2 - 2.9e-55 186.5 0.3 3.9e-55 186.1 0.2 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CBK22485.2 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK22485.2 - 1.5e-06 29.0 0.0 3e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK22485.2 - 1.5e-05 25.1 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22485.2 - 2.5e-05 24.3 0.1 0.0001 22.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CBK22485.2 - 3.2e-05 24.2 0.5 0.00031 21.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBK22485.2 - 0.00012 21.3 0.1 0.00028 20.1 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CBK22485.2 - 0.00027 20.6 0.2 0.00065 19.4 0.1 1.8 1 1 0 1 1 1 1 NTPase AAA PF00004.24 CBK22485.2 - 0.00037 20.6 0.6 0.0014 18.8 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CBK22485.2 - 0.00047 19.8 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBK22485.2 - 0.00075 19.8 0.1 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 CBK22485.2 - 0.00089 19.7 0.2 0.0023 18.3 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein AAA_14 PF13173.1 CBK22485.2 - 0.0009 19.1 0.4 0.0039 17.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBK22485.2 - 0.00094 19.3 0.1 0.0054 16.8 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Septin PF00735.13 CBK22485.2 - 0.0014 17.7 0.2 0.003 16.6 0.0 1.7 2 0 0 2 2 2 1 Septin Thymidylate_kin PF02223.12 CBK22485.2 - 0.0014 18.0 1.3 0.99 8.7 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_24 PF13479.1 CBK22485.2 - 0.0032 17.0 0.1 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBK22485.2 - 0.0032 17.1 0.4 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 CBK22485.2 - 0.0036 16.7 0.1 0.0097 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain DUF815 PF05673.8 CBK22485.2 - 0.0043 16.0 0.0 0.0075 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PTS_IIB PF02302.12 CBK22485.2 - 0.005 17.2 0.0 0.54 10.7 0.0 2.5 1 1 1 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit MMR_HSR1 PF01926.18 CBK22485.2 - 0.0052 16.7 0.1 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CBK22485.2 - 0.0064 16.1 0.1 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 CBK22485.2 - 0.0082 15.0 0.1 0.18 10.6 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.15 CBK22485.2 - 0.01 14.5 0.1 0.019 13.6 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.17 CBK22485.2 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CBK22485.2 - 0.013 15.0 0.3 0.098 12.1 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_2 PF07724.9 CBK22485.2 - 0.02 14.7 0.2 0.094 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 CBK22485.2 - 0.038 13.9 0.0 0.08 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 CBK22485.2 - 0.043 13.3 0.2 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 CBK22485.2 - 0.055 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 CBK22485.2 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 CBK22485.2 - 0.1 12.3 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBK22485.2 - 0.13 11.5 0.0 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CBK22485.2 - 0.21 10.7 1.4 7.6 5.7 0.0 3.1 2 2 2 4 4 4 0 ADP-ribosylation factor family AAA_23 PF13476.1 CBK22485.2 - 0.3 11.3 4.3 2.4 8.4 3.0 2.0 1 1 0 1 1 1 0 AAA domain PH PF00169.24 CBK22486.2 - 0.0002 21.5 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK22486.2 - 0.1 12.8 0.0 0.63 10.3 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain HSP70 PF00012.15 CBK22488.2 - 2e-53 181.2 0.0 4.4e-53 180.1 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22488.2 - 6.1e-07 28.3 0.0 1.2e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Ribosomal_S13 PF00416.17 CBK22489.2 - 5.1e-36 123.3 0.8 6.1e-36 123.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CBK22489.2 - 0.0019 16.8 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CBK22489.2 - 0.0049 16.8 0.1 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif DUF3556 PF12077.3 CBK22490.2 - 0.037 12.0 2.6 0.042 11.8 1.8 1.0 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) DRMBL PF07522.9 CBK22491.2 - 1.3e-12 47.7 0.0 3.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBK22491.2 - 1.2e-08 34.7 0.3 2e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK22491.2 - 0.096 12.3 0.3 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Amidohydro_1 PF01979.15 CBK22492.2 - 1.8e-47 162.6 1.8 2.2e-47 162.3 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CBK22492.2 - 1.4e-15 58.1 1.4 6.1e-12 46.1 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CBK22492.2 - 4.3e-15 55.8 3.2 7e-13 48.5 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CBK22492.2 - 6.7e-07 29.0 0.1 1.8e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase ASF1_hist_chap PF04729.8 CBK22493.2 - 4.2e-50 169.3 0.3 6.4e-50 168.7 0.2 1.3 1 1 0 1 1 1 1 ASF1 like histone chaperone SAC3_GANP PF03399.11 CBK22494.2 - 3.9e-41 140.8 5.9 4.9e-41 140.5 4.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TMP-TENI PF02581.12 CBK22495.2 - 6.3e-58 194.8 0.9 9.1e-58 194.3 0.6 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 CBK22495.2 - 0.028 13.4 2.9 0.055 12.5 1.0 1.9 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 CBK22495.2 - 0.14 11.1 0.2 0.52 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) HCO3_cotransp PF00955.16 CBK22496.2 - 2.1e-33 115.7 0.4 3.1e-33 115.1 0.3 1.2 1 0 0 1 1 1 1 HCO3- transporter family WD40 PF00400.27 CBK22496.2 - 1.2e-32 110.6 18.3 6.4e-10 38.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat HCO3_cotransp PF00955.16 CBK22497.2 - 6e-20 71.3 0.6 8.3e-20 70.9 0.4 1.2 1 0 0 1 1 1 1 HCO3- transporter family SAM_2 PF07647.12 CBK22497.2 - 0.00057 19.6 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) He_PIG PF05345.7 CBK22498.2 - 6.6e-16 58.0 41.7 1.5e-05 24.9 3.1 5.6 4 1 0 4 4 4 3 Putative Ig domain I-set PF07679.11 CBK22498.2 - 0.00024 20.8 2.6 2.8 7.8 0.0 5.6 5 0 0 5 5 5 1 Immunoglobulin I-set domain TMEM154 PF15102.1 CBK22498.2 - 0.0031 17.2 2.3 0.0031 17.2 1.6 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF912 PF06024.7 CBK22498.2 - 0.0072 16.3 0.9 0.015 15.3 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) F5_F8_type_C PF00754.20 CBK22498.2 - 0.018 14.9 37.0 0.061 13.1 3.2 6.2 7 1 0 7 7 6 0 F5/8 type C domain EphA2_TM PF14575.1 CBK22498.2 - 0.029 14.7 1.0 0.059 13.7 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CBK22498.2 - 0.031 13.9 3.5 0.069 12.7 2.4 1.5 1 0 0 1 1 1 0 Rifin/stevor family DUF1510 PF07423.6 CBK22498.2 - 0.044 13.1 0.5 0.08 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Baculo_11_kDa PF06143.6 CBK22498.2 - 0.072 12.4 3.2 0.15 11.4 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1180 PF06679.7 CBK22498.2 - 0.072 12.9 2.3 0.1 12.4 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) ODV-E18 PF10717.4 CBK22498.2 - 0.11 11.9 1.7 0.34 10.3 1.2 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OAD_gamma PF04277.8 CBK22498.2 - 0.41 11.0 4.4 1 9.7 3.1 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain P12 PF12669.2 CBK22498.2 - 0.61 10.3 3.8 1.1 9.4 2.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Ribosomal_S8 PF00410.14 CBK22500.2 - 9.1e-25 86.9 0.0 1.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 SecY PF00344.15 CBK22501.2 - 1.3e-84 284.0 12.8 2e-84 283.5 8.9 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBK22501.2 - 1.2e-18 66.2 0.2 4.2e-18 64.5 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p MNHE PF01899.11 CBK22501.2 - 0.099 12.2 2.3 0.11 12.1 0.2 2.2 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF1430 PF07242.6 CBK22501.2 - 1.5 8.9 6.9 7.4 6.7 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Pkinase PF00069.20 CBK22502.2 - 5.7e-43 146.9 0.0 7.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22502.2 - 1.5e-28 99.6 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK22502.2 - 0.00019 21.2 0.0 0.00059 19.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBK22502.2 - 0.0014 18.0 0.1 0.0036 16.6 0.0 1.6 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.9 CBK22502.2 - 0.015 14.3 0.2 0.025 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK22502.2 - 0.029 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBK22502.2 - 0.055 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBK22502.2 - 0.13 11.2 0.0 0.77 8.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 CBK22504.2 - 2.1e-45 154.8 0.0 2.6e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22504.2 - 6.8e-31 107.2 0.0 8.2e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ipi1_N PF12333.3 CBK22506.2 - 5.3 7.0 8.4 0.55 10.2 0.1 3.5 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation dsrm PF00035.20 CBK22507.2 - 6.9e-10 39.3 0.1 1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_M1 PF01433.15 CBK22508.2 - 2.8e-62 211.0 0.0 1.5e-61 208.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBK22508.2 - 1.3e-11 44.5 0.0 2.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Hydrolase PF00702.21 CBK22511.2 - 1.7e-20 74.3 0.1 2.3e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBK22511.2 - 8.9e-14 51.0 0.0 2.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBK22511.2 - 1.3e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK22511.2 - 3.7e-05 23.4 0.3 0.0003 20.4 0.2 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2726 PF10881.3 CBK22511.2 - 0.11 12.0 0.1 12 5.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2726) DNA_pol_B_exo1 PF03104.14 CBK22512.2 - 4.3e-52 176.9 0.4 1e-51 175.7 0.3 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.7 CBK22512.2 - 1.9e-35 122.1 0.0 5.1e-34 117.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.16 CBK22512.2 - 1.3e-21 76.9 0.0 5.3e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CBK22512.2 - 3.2e-07 30.1 1.2 3.6e-06 26.6 0.8 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CBK22512.2 - 1.3e-05 25.0 0.0 7.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 CBK22513.2 - 0.034 13.5 4.8 0.045 13.1 3.3 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger C1_1 PF00130.17 CBK22513.2 - 0.28 10.9 7.7 2.7 7.8 0.7 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 CBK22513.2 - 7.4 6.4 11.4 11 5.9 1.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 CBK22513.2 - 8.1 6.3 10.3 5.4 6.9 2.3 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Pro_isomerase PF00160.16 CBK22514.2 - 9.3e-45 152.6 0.0 9.3e-45 152.6 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ_CXXCXGXG PF00684.14 CBK22515.2 - 3.3e-11 43.0 10.0 5.6e-11 42.3 6.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBK22515.2 - 0.00029 20.4 3.5 0.012 15.3 0.1 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DnaJ PF00226.26 CBK22515.2 - 0.003 17.2 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Coiled PF05710.7 CBK22515.2 - 0.029 14.8 2.3 0.029 14.8 1.6 1.5 2 0 0 2 2 1 0 Coiled coil DZR PF12773.2 CBK22515.2 - 0.14 11.9 10.3 2.2 8.1 7.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon PHF5 PF03660.9 CBK22515.2 - 0.18 11.9 4.1 0.31 11.1 2.9 1.4 1 0 0 1 1 1 0 PHF5-like protein FdhE PF04216.7 CBK22515.2 - 1.4 8.5 7.8 12 5.5 4.7 2.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation OrfB_Zn_ribbon PF07282.6 CBK22515.2 - 1.7 8.3 14.6 2.5 7.8 3.7 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain NRDD PF13597.1 CBK22515.2 - 2.5 6.0 10.4 3.8 5.4 3.9 2.0 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase zf-IS66 PF13005.2 CBK22515.2 - 3.5 7.6 14.5 11 6.0 0.0 4.2 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.1 CBK22515.2 - 6.1 7.2 12.9 1.5e+03 -0.5 9.0 3.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 CBK22515.2 - 7.2 6.1 11.6 35 4.0 0.3 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-RING_3 PF14369.1 CBK22515.2 - 8.4 6.4 19.0 4.3 7.4 0.4 4.0 2 2 2 4 4 4 0 zinc-finger Aminotran_5 PF00266.14 CBK22516.2 - 4.7e-34 117.7 0.0 6.7e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MORN PF02493.15 CBK22516.2 - 1.3e-16 59.1 34.0 0.0046 16.5 3.7 9.0 8 0 0 8 8 8 8 MORN repeat GST_C_2 PF13410.1 CBK22517.2 - 2.1e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBK22517.2 - 2.2e-05 24.8 0.0 4.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBK22517.2 - 0.00098 19.0 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 CBK22519.2 - 9.5e-10 37.9 5.2 0.00027 20.6 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBK22519.2 - 0.0063 16.2 0.0 0.43 10.3 0.0 3.1 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region U-box PF04564.10 CBK22520.2 - 0.0047 16.8 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 U-box domain MutS_III PF05192.13 CBK22521.2 - 0.028 14.1 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 MutS domain III SCHIP-1 PF10148.4 CBK22521.2 - 0.054 12.8 0.4 0.054 12.8 0.3 1.8 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Pap_E4 PF02711.9 CBK22521.2 - 0.11 13.3 0.7 0.36 11.6 0.5 1.9 1 0 0 1 1 1 0 E4 protein ORC6 PF05460.8 CBK22521.2 - 0.15 11.1 3.6 0.25 10.4 2.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CK_II_beta PF01214.13 CBK22522.2 - 2.7e-38 131.3 0.0 3.1e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit TerY-C PF15616.1 CBK22522.2 - 0.037 13.9 0.2 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 CBK22522.2 - 0.041 13.4 3.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF932 PF06067.6 CBK22522.2 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) RabGAP-TBC PF00566.13 CBK22523.2 - 3.9e-30 104.9 6.6 3.9e-30 104.9 4.6 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain G-patch PF01585.18 CBK22523.2 - 1.4e-12 47.2 5.0 3e-12 46.1 3.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK22523.2 - 9.1e-09 35.0 2.1 9.1e-09 35.0 1.5 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site Rhodanese PF00581.15 CBK22523.2 - 8.4e-07 29.3 1.8 1.2e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain eIF-1a PF01176.14 CBK22524.2 - 1.5e-14 53.1 0.3 2.9e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 Kdo PF06293.9 CBK22524.2 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2076 PF09849.4 CBK22524.2 - 0.42 10.6 6.3 0.6 10.1 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4637 PF15470.1 CBK22524.2 - 2.6 7.6 10.1 3.9 7.0 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cwf_Cwc_15 PF04889.7 CBK22524.2 - 3.2 7.3 13.1 3.9 7.1 9.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein tRNA-synt_1e PF01406.14 CBK22525.2 - 5.7e-100 334.3 0.2 8.2e-100 333.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBK22525.2 - 2.6e-12 46.0 0.0 3.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBK22525.2 - 5.5e-05 21.3 0.2 0.0002 19.5 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) PhaP_Bmeg PF09602.5 CBK22525.2 - 0.0087 15.8 0.7 0.021 14.6 0.5 1.6 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) LXG PF04740.7 CBK22525.2 - 0.015 15.0 0.2 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 LXG domain of WXG superfamily tRNA-synt_1f PF01921.13 CBK22525.2 - 0.018 13.6 0.0 0.049 12.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) PTRF_SDPR PF15237.1 CBK22525.2 - 0.04 13.3 0.3 0.094 12.1 0.2 1.6 1 0 0 1 1 1 0 PTRF/SDPR family HSP70 PF00012.15 CBK22526.2 - 6.3e-54 182.9 0.0 8.1e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22526.2 - 2.6e-11 42.6 0.0 3.8e-09 35.6 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBK22526.2 - 0.00025 20.8 2.4 0.017 14.9 0.1 3.0 3 1 0 3 3 3 2 Cell division protein FtsA HSP70 PF00012.15 CBK22527.2 - 2.9e-24 84.9 0.1 5.2e-24 84.1 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22527.2 - 0.016 13.7 0.0 0.063 11.8 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Aha1_N PF09229.6 CBK22527.2 - 1.6 8.5 5.3 0.83 9.4 0.1 2.7 2 1 0 3 3 3 0 Activator of Hsp90 ATPase, N-terminal IF-2B PF01008.12 CBK22528.2 - 6.8e-25 87.6 0.0 7.8e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CSD PF00313.17 CBK22529.2 - 0.00044 19.9 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Ribosomal_L21p PF00829.16 CBK22530.2 - 7.5e-28 96.5 1.1 1e-27 96.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein AAA PF00004.24 CBK22531.2 - 1.6e-15 57.4 0.0 3.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CBK22531.2 - 7.7e-12 45.1 0.0 3.1e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CBK22531.2 - 7.1e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CBK22531.2 - 1e-06 28.9 0.0 2.9e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK22531.2 - 7.6e-06 25.6 0.0 1.6e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22531.2 - 1.6e-05 24.9 0.1 0.0001 22.3 0.0 2.2 2 2 1 3 3 3 1 AAA ATPase domain ResIII PF04851.10 CBK22531.2 - 4.7e-05 23.3 0.0 0.00016 21.6 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 CBK22531.2 - 0.00014 20.6 0.0 0.17 10.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 CBK22531.2 - 0.00087 19.0 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBK22531.2 - 0.0009 19.1 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBK22531.2 - 0.0011 18.7 0.0 0.0055 16.4 0.0 2.1 2 1 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 CBK22531.2 - 0.0011 19.2 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.16 CBK22531.2 - 0.0013 17.9 0.0 0.0084 15.2 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBK22531.2 - 0.0033 16.5 0.1 0.013 14.5 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 CBK22531.2 - 0.0037 16.8 0.0 0.0081 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBK22531.2 - 0.0041 15.8 0.0 1.8 7.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBK22531.2 - 0.0098 15.3 0.3 2.9 7.2 0.0 2.8 1 1 1 3 3 3 1 AAA-like domain AAA_5 PF07728.9 CBK22531.2 - 0.019 14.7 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK22531.2 - 0.024 14.9 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBK22531.2 - 0.037 12.9 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SNF2_N PF00176.18 CBK22531.2 - 0.061 12.1 0.0 4.8 5.8 0.0 2.2 1 1 1 2 2 2 0 SNF2 family N-terminal domain zf-CCHC_4 PF14392.1 CBK22531.2 - 0.067 12.8 0.1 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle AAA_18 PF13238.1 CBK22531.2 - 0.074 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK22531.2 - 0.077 11.9 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CBK22531.2 - 0.083 12.2 0.1 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF4187 PF13821.1 CBK22531.2 - 0.086 12.4 0.1 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) AAA_28 PF13521.1 CBK22531.2 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBK22531.2 - 0.13 13.1 0.0 0.32 11.8 0.0 1.9 1 1 1 2 2 1 0 AAA domain Na_H_antiporter PF03553.9 CBK22532.2 - 8.2e-49 166.2 13.6 8.2e-49 166.2 9.5 2.6 1 1 1 2 2 2 1 Na+/H+ antiporter family MscS_TM PF12794.2 CBK22532.2 - 5 5.6 16.9 3.4 6.1 0.9 3.8 4 0 0 4 4 4 0 Mechanosensitive ion channel inner membrane domain 1 ABC1 PF03109.11 CBK22533.2 - 1.9e-22 79.4 0.0 3.2e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 CBK22534.2 - 0.033 13.3 0.1 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Methyltransf_23 PF13489.1 CBK22535.2 - 2.9e-13 49.8 0.1 4.2e-13 49.3 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK22535.2 - 5.5e-10 39.6 0.1 6.6e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22535.2 - 6.6e-06 26.6 0.0 2e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK22535.2 - 4.2e-05 23.8 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK22535.2 - 5.2e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK22535.2 - 0.00092 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ORF6N PF10543.4 CBK22535.2 - 0.0011 18.9 0.4 0.08 12.9 0.3 2.4 1 1 0 1 1 1 1 ORF6N domain Methyltransf_26 PF13659.1 CBK22535.2 - 0.0042 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CBK22535.2 - 0.0053 15.7 0.1 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 CBK22535.2 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBK22535.2 - 0.068 12.3 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF4457 PF14652.1 CBK22536.2 - 3.1e-112 374.7 0.0 3.6e-112 374.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) Sad1_UNC PF07738.8 CBK22536.2 - 0.078 12.7 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal AhpC-TSA PF00578.16 CBK22537.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK22537.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK22537.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_pol_B_2 PF03175.8 CBK22538.2 - 6.7e-09 34.9 10.0 0.0019 16.9 0.1 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral ACBP PF00887.14 CBK22540.2 - 1.7e-29 101.3 0.4 1.8e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4090 PF13319.1 CBK22541.2 - 0.0091 15.9 1.0 0.011 15.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) IATP PF04568.7 CBK22541.2 - 0.021 14.8 5.4 0.024 14.6 3.4 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4460 PF14687.1 CBK22541.2 - 0.079 12.7 1.2 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) RabGAP-TBC PF00566.13 CBK22543.2 - 7.7e-19 68.0 0.1 2.9e-18 66.1 0.0 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PDZ PF00595.19 CBK22543.2 - 0.013 15.6 0.6 0.69 10.1 0.0 2.6 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBK22543.2 - 0.017 14.9 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 PDZ domain RabGAP-TBC PF00566.13 CBK22544.2 - 2.5e-14 53.2 1.8 2.8e-14 53.1 1.2 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1772 PF08592.6 CBK22544.2 - 0.033 13.9 0.2 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Glyco_hydro_35 PF01301.14 CBK22545.2 - 1.6e-68 231.4 3.4 2.3e-68 230.8 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CBK22545.2 - 3.1e-08 33.8 3.6 0.0011 19.2 0.1 3.3 3 0 0 3 3 3 3 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.10 CBK22545.2 - 3.2e-05 23.2 0.2 6.2e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_N PF02837.13 CBK22545.2 - 0.0024 17.4 5.8 0.0095 15.5 0.1 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 2, sugar binding domain Xpo1 PF08389.7 CBK22546.2 - 2.4e-13 50.2 6.4 1.2e-11 44.6 2.3 2.7 2 0 0 2 2 2 2 Exportin 1-like protein HEAT_2 PF13646.1 CBK22546.2 - 0.0077 16.4 0.1 0.37 11.0 0.0 3.2 2 1 0 3 3 3 1 HEAT repeats Arm PF00514.18 CBK22546.2 - 0.022 14.5 0.3 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 CBK22546.2 - 0.024 14.5 3.1 0.028 14.3 0.1 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain UTP15_C PF09384.5 CBK22546.2 - 0.054 13.1 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 UTP15 C terminal AAA_5 PF07728.9 CBK22548.2 - 8.8e-12 44.9 0.0 9.9e-05 22.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Synaptobrevin PF00957.16 CBK22549.2 - 3.4e-11 42.5 0.0 4e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Sedlin_N PF04628.8 CBK22550.2 - 0.003 17.4 0.2 0.0049 16.7 0.1 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region G10 PF01125.12 CBK22551.2 - 4.8e-49 165.6 9.0 5.4e-49 165.4 6.2 1.0 1 0 0 1 1 1 1 G10 protein IRF-2BP1_2 PF11261.3 CBK22551.2 - 0.066 12.6 2.4 0.11 11.9 1.7 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger DUF2387 PF09526.5 CBK22551.2 - 0.2 11.6 0.4 0.2 11.6 0.3 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Tmpp129 PF10272.4 CBK22551.2 - 4.7 5.8 10.7 5.5 5.6 7.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor CBFD_NFYB_HMF PF00808.18 CBK22553.2 - 1.4e-25 89.1 0.1 1.7e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK22553.2 - 1.4e-06 28.3 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CBK22553.2 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PAN_3 PF08277.7 CBK22553.2 - 0.058 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 PAN-like domain GED PF02212.13 CBK22554.2 - 1.5e-22 79.2 3.8 3.1e-22 78.2 2.6 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.24 CBK22554.2 - 5.8e-06 26.4 0.1 1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK22554.2 - 0.0037 17.4 1.6 0.015 15.5 1.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain REV PF00424.13 CBK22554.2 - 0.028 14.3 0.3 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PH_8 PF15409.1 CBK22554.2 - 0.043 13.8 0.5 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Dynamin_N PF00350.18 CBK22555.2 - 2.1e-51 174.0 0.0 3e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CBK22555.2 - 1.9e-27 95.8 0.1 2.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 CBK22555.2 - 0.00012 22.0 0.1 0.00041 20.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBK22555.2 - 0.021 15.3 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CBK22555.2 - 0.025 13.8 0.2 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B 2-oxoacid_dh PF00198.18 CBK22556.2 - 6.5e-71 238.2 0.2 8.6e-71 237.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBK22556.2 - 5.3e-17 61.2 0.3 1.3e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CBK22556.2 - 7.7e-10 38.2 0.1 1.7e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CBK22556.2 - 5.9e-08 32.2 0.1 2.2e-06 27.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CBK22556.2 - 0.0016 17.7 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CBK22556.2 - 0.0024 18.2 0.3 0.033 14.5 0.2 2.5 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK22556.2 - 0.0041 16.3 0.0 0.0081 15.3 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein PYNP_C PF07831.8 CBK22556.2 - 0.1 12.0 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain QRPTase_N PF02749.11 CBK22556.2 - 0.16 11.8 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain PAT1 PF09770.4 CBK22556.2 - 0.93 7.6 10.7 1.2 7.2 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CBK22556.2 - 1.1 9.1 5.4 1.3 8.8 3.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2360 PF10152.4 CBK22556.2 - 1.5 9.0 10.7 0.43 10.8 5.0 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Histone PF00125.19 CBK22558.2 - 3.5e-33 113.5 0.8 5.5e-33 112.9 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK22558.2 - 2.9e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK22558.2 - 0.0043 17.0 0.1 0.0087 16.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBK22558.2 - 0.14 11.4 1.1 0.35 10.0 0.1 1.7 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T PIG-Y PF15159.1 CBK22559.2 - 0.023 14.8 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y UPF0242 PF06785.6 CBK22559.2 - 0.085 11.5 0.6 0.1 11.2 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) EPL1 PF10513.4 CBK22560.2 - 4.9e-14 52.8 0.3 9.6e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like KH_1 PF00013.24 CBK22561.2 - 1.7e-05 24.3 1.3 3.5e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 KH domain tRNA-synt_2b PF00587.20 CBK22562.2 - 1.4e-37 128.9 0.1 2.1e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBK22562.2 - 2.1e-24 85.5 4.6 4.1e-24 84.6 3.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.6 CBK22562.2 - 0.26 10.0 4.7 0.42 9.3 3.3 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein IncA PF04156.9 CBK22562.2 - 0.72 9.4 2.5 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein zf-Sec23_Sec24 PF04810.10 CBK22563.2 - 3.1e-05 23.4 1.2 6.1e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CBK22563.2 - 0.0068 16.8 0.4 0.12 12.8 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Zn_Tnp_IS1595 PF12760.2 CBK22563.2 - 0.26 11.1 3.3 0.52 10.1 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Gelsolin PF00626.17 CBK22564.2 - 2.6e-06 27.0 0.0 7.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat DUF4573 PF15140.1 CBK22565.2 - 0.0068 16.0 6.2 0.011 15.3 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) Thioredoxin PF00085.15 CBK22566.2 - 2.4e-16 59.2 0.1 4.2e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CBK22566.2 - 2.5e-06 27.9 0.6 5.8e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_3 PF13192.1 CBK22566.2 - 0.024 14.4 1.4 7.4 6.4 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin domain Mito_carr PF00153.22 CBK22567.2 - 1.3e-43 146.6 3.0 6.2e-16 57.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PS_Dcarbxylase PF02666.10 CBK22568.2 - 1.8e-46 157.9 0.0 2.4e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.17 CBK22568.2 - 0.044 13.4 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF4187 PF13821.1 CBK22569.2 - 5.4e-17 61.1 3.1 5.4e-17 61.1 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CBK22569.2 - 1.1e-15 57.0 6.6 2.3e-15 56.0 4.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK22569.2 - 2.6e-08 33.5 1.1 6.3e-08 32.3 0.8 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-C2H2_jaz PF12171.3 CBK22569.2 - 0.076 13.1 3.3 0.15 12.2 2.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DNA_pol_B PF00136.16 CBK22570.2 - 9.2e-110 367.5 3.3 1.4e-109 367.0 2.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBK22570.2 - 0.00011 21.2 0.0 0.00011 21.2 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain Metallophos PF00149.23 CBK22571.2 - 2.8e-41 141.1 0.3 4e-41 140.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Apc3 PF12895.2 CBK22572.2 - 0.014 15.4 0.9 0.025 14.7 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBK22572.2 - 0.093 12.6 0.2 7.2 6.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF758 PF05527.6 CBK22572.2 - 0.12 11.9 3.0 0.15 11.6 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF758) Glycoprotein PF03409.10 CBK22572.2 - 0.14 10.8 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein Peptidase_M41 PF01434.13 CBK22573.2 - 4.6e-58 196.1 0.0 7e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBK22573.2 - 6e-38 130.0 0.1 1.7e-37 128.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK22573.2 - 2.1e-05 24.2 0.0 7.9e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK22573.2 - 6.5e-05 22.0 0.0 0.00016 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK22573.2 - 9.7e-05 22.5 0.1 0.0037 17.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK22573.2 - 9.8e-05 22.0 0.6 0.00037 20.1 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CBK22573.2 - 0.00023 19.9 0.0 0.00043 19.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CBK22573.2 - 0.0003 21.6 0.0 0.0013 19.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22573.2 - 0.00042 20.3 1.7 0.0075 16.2 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CBK22573.2 - 0.00098 18.3 0.3 0.0021 17.2 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CBK22573.2 - 0.0022 17.4 0.1 0.007 15.7 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBK22573.2 - 0.0071 16.2 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK22573.2 - 0.0083 16.0 0.0 0.036 13.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBK22573.2 - 0.0097 15.8 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBK22573.2 - 0.022 14.4 1.6 3.1 7.4 0.1 3.3 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.1 CBK22573.2 - 0.026 14.4 0.1 0.066 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 CBK22573.2 - 0.029 14.6 0.5 0.13 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 CBK22573.2 - 0.032 13.3 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC ATP-synt_8 PF00895.15 CBK22573.2 - 0.054 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 Sigma54_activat PF00158.21 CBK22573.2 - 0.056 12.9 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 CBK22573.2 - 0.091 12.3 0.4 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBK22573.2 - 0.16 11.3 5.1 0.95 8.8 0.2 3.4 3 1 2 5 5 4 0 AAA domain HEAT PF02985.17 CBK22575.2 - 1.4e-07 30.9 2.7 1.3 9.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CBK22575.2 - 5.7e-07 29.7 0.4 0.76 10.0 0.0 5.3 2 2 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 CBK22575.2 - 5.7e-05 23.4 0.6 1.6 9.3 0.0 5.9 5 1 1 6 6 6 1 HEAT-like repeat DUF2454 PF10521.4 CBK22575.2 - 0.00085 18.4 0.3 0.9 8.4 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2454) FliH PF02108.11 CBK22575.2 - 0.034 14.0 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH DUF3385 PF11865.3 CBK22575.2 - 0.63 9.9 7.4 0.18 11.7 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) DNA_pol_phi PF04931.8 CBK22576.2 - 1.1e-11 43.3 34.3 1.4e-11 42.9 23.8 1.3 1 0 0 1 1 1 1 DNA polymerase phi DUF1510 PF07423.6 CBK22576.2 - 0.0018 17.6 21.7 0.0046 16.3 15.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CENP-T PF15511.1 CBK22576.2 - 0.016 14.5 14.5 0.023 13.9 10.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Zip PF02535.17 CBK22576.2 - 0.044 12.7 1.5 0.056 12.4 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CBK22576.2 - 0.095 12.4 9.4 0.017 14.9 3.6 1.9 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.1 CBK22576.2 - 0.91 9.6 11.6 0.26 11.4 6.0 1.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GAGA_bind PF06217.7 CBK22576.2 - 1.2 9.0 5.5 2.2 8.1 3.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family PH_7 PF15408.1 CBK22577.2 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Leuk-A4-hydro_C PF09127.6 CBK22578.2 - 0.04 13.4 0.1 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Ribosomal_L28e PF01778.12 CBK22579.2 - 4.6e-32 110.8 3.0 4.6e-32 110.8 2.1 1.9 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CBK22579.2 - 2.8e-19 69.0 14.3 2.8e-19 69.0 9.9 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.10 CBK22579.2 - 0.33 10.1 6.6 0.45 9.6 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRICHOS PF04089.9 CBK22579.2 - 1.8 8.5 6.7 2.5 8.0 0.1 3.0 2 1 1 3 3 3 0 BRICHOS domain DUF4168 PF13767.1 CBK22579.2 - 2.3 8.9 7.0 4.1 8.0 2.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Pkinase PF00069.20 CBK22581.2 - 8.4e-74 247.9 0.0 1.1e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22581.2 - 1.2e-40 139.2 0.0 1.7e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22581.2 - 1.6e-06 27.3 0.0 1.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 CBK22581.2 - 0.0003 20.9 0.0 0.00071 19.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1940 PF09155.5 CBK22581.2 - 0.021 14.6 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) APH PF01636.18 CBK22581.2 - 0.028 14.1 0.0 2.5 7.7 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family GST_N PF02798.15 CBK22582.2 - 4e-08 33.3 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBK22582.2 - 3.6e-06 27.1 0.0 6.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBK22582.2 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain YdjC PF04794.7 CBK22583.2 - 3e-30 105.5 0.0 3.3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein Glycos_transf_1 PF00534.15 CBK22584.2 - 2.6e-12 46.5 0.0 3.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBK22584.2 - 1.7e-06 28.1 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBK22584.2 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 HSP20 PF00011.16 CBK22585.2 - 3.3e-17 62.2 0.2 4.2e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 CBK22585.2 - 0.11 12.0 1.2 0.12 11.9 0.2 1.5 2 0 0 2 2 2 0 GvpH ADK PF00406.17 CBK22586.2 - 7.3e-30 103.8 0.0 1.6e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CBK22586.2 - 6.7e-08 32.8 0.0 2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Tub PF01167.13 CBK22586.2 - 4.5e-07 29.1 0.0 1.2e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Tub family AAA_33 PF13671.1 CBK22586.2 - 0.00011 22.1 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK22586.2 - 0.00032 21.5 0.1 0.0013 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain BTB PF00651.26 CBK22586.2 - 0.02 14.8 0.1 0.064 13.2 0.1 1.9 1 1 0 1 1 1 0 BTB/POZ domain GCD14 PF08704.5 CBK22587.2 - 1.6e-75 253.8 0.6 3.1e-70 236.4 0.0 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CBK22587.2 - 3.7e-08 33.0 0.0 9e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBK22587.2 - 2.9e-05 24.8 0.1 0.0001 23.0 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK22587.2 - 0.00013 22.0 0.0 0.0004 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22587.2 - 0.00018 22.0 0.0 0.00036 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK22587.2 - 0.00024 20.5 0.0 0.00074 18.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 CBK22587.2 - 0.0013 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.1 CBK22587.2 - 0.0091 15.5 0.1 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term RrnaAD PF00398.15 CBK22587.2 - 0.03 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 CBK22587.2 - 0.032 13.3 0.0 0.084 11.9 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) XRN_N PF03159.13 CBK22587.2 - 3 7.1 8.3 0.56 9.5 0.7 2.5 2 1 1 3 3 3 0 XRN 5'-3' exonuclease N-terminus CDC45 PF02724.9 CBK22587.2 - 3.2 5.6 10.8 4.3 5.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CBK22587.2 - 4.9 4.6 12.2 6.4 4.3 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CBK22587.2 - 5 6.4 19.1 7.8 5.7 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 CBK22587.2 - 7.2 6.0 18.0 12 5.2 12.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CBK22587.2 - 8.9 4.6 24.7 12 4.2 17.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF2201_N PF13203.1 CBK22587.2 - 8.9 5.3 11.6 13 4.8 8.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NUDIX PF00293.23 CBK22588.2 - 9.6e-05 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain LRR_5 PF13306.1 CBK22589.2 - 1.7e-08 34.1 2.8 0.00028 20.5 0.1 4.0 1 1 1 3 3 3 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBK22589.2 - 5.2e-05 22.9 3.9 2.3 8.0 0.0 5.6 5 1 1 6 6 6 3 Leucine rich repeat Peptidase_A3 PF02160.10 CBK22589.2 - 0.082 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) GDC-P PF02347.11 CBK22590.2 - 7.4e-181 601.5 0.2 1.7e-170 567.4 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CBK22590.2 - 8.1e-08 31.3 1.7 0.00042 19.1 0.1 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBK22590.2 - 0.00027 20.1 0.1 0.00027 20.1 0.0 2.2 3 0 0 3 3 3 1 Beta-eliminating lyase DEAD PF00270.24 CBK22591.2 - 3.5e-37 127.5 0.1 1.8e-35 121.9 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK22591.2 - 3.5e-12 46.0 0.0 9.4e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK22591.2 - 7.3e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBK22591.2 - 1.2e-05 24.2 0.1 1.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-HIT PF04438.11 CBK22592.2 - 7e-08 31.9 1.7 8.7e-08 31.6 1.2 1.2 1 0 0 1 1 1 1 HIT zinc finger DUF2116 PF09889.4 CBK22592.2 - 0.033 13.9 5.0 0.11 12.3 3.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Toprim_C_rpt PF13368.1 CBK22592.2 - 0.034 14.6 0.0 0.048 14.1 0.0 1.3 1 1 0 1 1 1 0 Topoisomerase C-terminal repeat Prok-RING_2 PF14445.1 CBK22592.2 - 0.57 10.1 3.0 1.2 9.1 1.8 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 MCM PF00493.18 CBK22593.2 - 2.4e-128 427.5 0.0 4.3e-128 426.7 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBK22593.2 - 7.1e-20 71.6 0.4 2.7e-19 69.8 0.2 2.1 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBK22593.2 - 8.7e-09 34.8 0.1 1.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBK22593.2 - 1.5e-06 27.9 0.1 8.7e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zn-ribbon_8 PF09723.5 CBK22593.2 - 0.0028 17.5 2.3 0.0074 16.2 1.6 1.6 1 0 0 1 1 1 1 Zinc ribbon domain AAA_3 PF07726.6 CBK22593.2 - 0.0028 17.2 0.0 0.008 15.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SIR2 PF02146.12 CBK22593.2 - 0.011 15.4 0.2 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Sir2 family Sigma54_activat PF00158.21 CBK22593.2 - 0.024 14.1 0.0 7.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 CBK22593.2 - 0.029 14.5 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhnA_Zn_Ribbon PF08274.7 CBK22593.2 - 0.31 10.8 2.3 19 5.1 0.1 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon AAA_16 PF13191.1 CBK22593.2 - 0.32 10.9 1.6 8 6.3 0.0 3.3 3 1 0 4 4 4 0 AAA ATPase domain Ribosomal_L23 PF00276.15 CBK22594.2 - 5.2e-17 61.5 2.2 1.2e-16 60.4 1.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 RabGAP-TBC PF00566.13 CBK22596.2 - 1.2e-28 100.1 1.5 3.4e-28 98.5 1.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PIG-L PF02585.12 CBK22596.2 - 4.1e-21 75.8 0.0 1e-20 74.5 0.0 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1515 PF07439.6 CBK22596.2 - 0.51 10.1 4.0 1.3 8.8 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) DnaJ PF00226.26 CBK22597.2 - 6.7e-28 96.2 3.5 9.7e-28 95.7 2.5 1.2 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.4 CBK22597.2 - 6.2e-06 25.9 41.4 0.00037 20.1 11.9 3.4 1 1 1 3 3 3 3 Transmembrane Fragile-X-F protein RPT PF13446.1 CBK22597.2 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein Aldo_ket_red PF00248.16 CBK22598.2 - 5.7e-51 173.0 0.0 7.2e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3581 PF12119.3 CBK22598.2 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) LRR_8 PF13855.1 CBK22599.2 - 6e-06 25.9 1.4 0.0074 16.0 0.2 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK22599.2 - 0.00077 19.0 5.1 2.6 7.7 0.0 4.2 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBK22599.2 - 0.033 14.2 1.2 37 4.8 0.0 4.4 3 2 1 5 5 5 0 Leucine Rich repeat hSac2 PF12456.3 CBK22599.2 - 0.043 13.2 0.1 5.3 6.4 0.0 2.7 2 1 1 3 3 3 0 Inositol phosphatase DNA_pol_B_2 PF03175.8 CBK22600.2 - 4e-09 35.6 6.6 0.0023 16.6 2.1 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.8 CBK22601.2 - 1.9e-08 33.4 8.1 0.0066 15.1 0.0 3.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Ifi-6-16 PF06140.8 CBK22602.2 - 8.8e-05 22.2 28.2 8.8e-05 22.2 19.6 2.4 1 1 2 3 3 3 1 Interferon-induced 6-16 family ubiquitin PF00240.18 CBK22603.2 - 1.2e-09 37.4 0.1 1.3e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK22603.2 - 0.016 14.8 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2340 PF10209.4 CBK22603.2 - 0.055 13.6 0.1 0.068 13.3 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Ubiquitin_2 PF14560.1 CBK22603.2 - 0.075 13.2 0.1 0.49 10.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Glucosamine_iso PF01182.15 CBK22604.2 - 6.2e-18 65.2 0.0 6.8e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RNase_Zc3h12a PF11977.3 CBK22605.2 - 1.5e-05 24.8 0.0 5.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF1980 PF09323.5 CBK22605.2 - 0.012 15.4 0.6 0.032 13.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) RRM_1 PF00076.17 CBK22606.2 - 1.4e-18 66.3 0.1 2.1e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK22606.2 - 6.4e-15 54.8 0.0 9.6e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22606.2 - 7.8e-12 44.8 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK22606.2 - 0.018 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 OB_RNB PF08206.6 CBK22606.2 - 0.039 13.4 0.1 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain DEAD PF00270.24 CBK22607.2 - 2.3e-40 137.8 0.0 7.4e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK22607.2 - 1.2e-29 102.0 0.1 6.6e-29 99.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBK22607.2 - 0.028 12.8 0.0 0.48 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CBK22607.2 - 0.03 14.4 0.1 0.076 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 CBK22608.2 - 9.6e-08 31.8 1.6 1.2e-07 31.5 1.1 1.1 1 0 0 1 1 1 1 IncA protein GOLD_2 PF13897.1 CBK22608.2 - 0.00015 21.9 8.9 0.11 12.6 0.0 3.3 3 0 0 3 3 3 2 Golgi-dynamics membrane-trafficking Spc7 PF08317.6 CBK22608.2 - 0.00054 18.7 9.1 0.00078 18.1 6.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein EMP24_GP25L PF01105.19 CBK22608.2 - 0.0015 18.2 4.0 0.0088 15.7 2.8 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Phlebovirus_NSM PF07246.6 CBK22608.2 - 0.0046 16.1 2.5 0.0073 15.5 1.7 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF342 PF03961.8 CBK22608.2 - 0.0053 15.2 2.1 0.007 14.8 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ADIP PF11559.3 CBK22608.2 - 0.0064 16.4 6.3 0.0098 15.7 4.3 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 CBK22608.2 - 0.0098 14.4 4.6 0.013 13.9 3.2 1.1 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.7 CBK22608.2 - 0.011 15.4 4.8 0.015 15.0 2.1 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF848 PF05852.6 CBK22608.2 - 0.013 15.3 7.1 0.021 14.6 5.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 CBK22608.2 - 0.018 14.0 9.9 0.027 13.5 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF919 PF06034.6 CBK22608.2 - 0.018 14.6 6.0 0.046 13.3 4.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Reo_sigmaC PF04582.7 CBK22608.2 - 0.029 13.5 1.4 0.04 13.0 1.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_23 PF13476.1 CBK22608.2 - 0.032 14.5 2.2 0.044 14.1 1.5 1.3 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CBK22608.2 - 0.041 12.8 8.2 0.062 12.2 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2730 PF10805.3 CBK22608.2 - 0.043 13.5 2.8 0.18 11.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4200 PF13863.1 CBK22608.2 - 0.043 13.7 14.2 0.046 13.6 8.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COG5 PF10392.4 CBK22608.2 - 0.044 13.7 2.3 0.066 13.1 1.6 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TBPIP PF07106.8 CBK22608.2 - 0.065 12.7 9.7 0.11 12.0 6.7 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 CBK22608.2 - 0.07 12.3 10.4 0.11 11.6 7.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CBK22608.2 - 0.076 10.8 3.0 0.091 10.6 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 CBK22608.2 - 0.09 12.5 11.5 0.15 11.8 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMPIT PF07851.8 CBK22608.2 - 0.095 11.7 5.5 0.14 11.2 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4201 PF13870.1 CBK22608.2 - 0.2 11.0 10.6 0.3 10.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) FliJ PF02050.11 CBK22608.2 - 0.21 11.6 9.4 0.34 10.9 6.5 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3450 PF11932.3 CBK22608.2 - 0.21 10.7 3.9 0.35 10.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.4 CBK22608.2 - 0.44 8.8 6.8 0.64 8.3 4.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Syntaxin-6_N PF09177.6 CBK22608.2 - 0.59 10.5 5.6 1.2 9.6 3.9 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 CBK22608.2 - 0.63 10.0 8.5 1.2 9.2 5.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 CBK22608.2 - 0.65 10.3 8.9 0.2 12.0 3.8 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF972) DUF3847 PF12958.2 CBK22608.2 - 0.67 9.7 9.9 0.093 12.4 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) DUF641 PF04859.7 CBK22608.2 - 0.8 9.4 6.9 1.5 8.6 4.8 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) YscO PF07321.7 CBK22608.2 - 1 9.2 12.0 3.8 7.3 8.3 1.8 1 1 0 1 1 1 0 Type III secretion protein YscO DivIC PF04977.10 CBK22608.2 - 1 8.8 11.9 1.4 8.4 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 CBK22608.2 - 1.2 9.2 10.4 0.44 10.6 3.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 CBK22608.2 - 2.1 8.1 15.6 6.7 6.5 2.8 2.4 1 1 1 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 CBK22608.2 - 3.5 8.1 7.2 7.4 7.0 2.9 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cauli_DNA-bind PF03310.8 CBK22608.2 - 5.6 6.8 8.9 10 6.0 1.1 2.2 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Pox_A_type_inc PF04508.7 CBK22608.2 - 6.3 6.8 8.1 2.2 8.2 1.4 2.8 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat Laps PF10169.4 CBK22608.2 - 8.1 6.6 10.0 0.92 9.7 2.0 2.1 1 1 1 2 2 2 0 Learning-associated protein Yippee-Mis18 PF03226.9 CBK22609.2 - 0.017 15.1 0.1 0.071 13.1 0.0 1.9 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TPT PF03151.11 CBK22610.2 - 7.9e-13 48.3 10.4 1.2e-12 47.7 7.2 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 CBK22610.2 - 6.8e-05 22.9 7.1 8.6e-05 22.5 5.0 1.1 1 0 0 1 1 1 1 EamA-like transporter family UAA PF08449.6 CBK22610.2 - 0.0021 17.0 4.5 0.0026 16.7 3.1 1.1 1 0 0 1 1 1 1 UAA transporter family DUF2427 PF10348.4 CBK22610.2 - 1 8.9 5.6 2.2 7.8 3.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Homeobox_KN PF05920.6 CBK22611.2 - 3e-16 58.8 0.3 6.5e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBK22611.2 - 5.9e-07 29.0 2.1 7.8e-07 28.6 0.3 1.9 2 0 0 2 2 2 1 Homeobox domain EamA PF00892.15 CBK22611.2 - 9e-06 25.7 11.9 1.5e-05 24.9 8.3 1.4 1 0 0 1 1 1 1 EamA-like transporter family zf-H2C2_2 PF13465.1 CBK22612.2 - 1.8e-31 106.8 30.2 1.1e-07 31.7 0.2 6.4 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.21 CBK22612.2 - 1.6e-14 53.2 36.1 0.0011 19.1 0.1 6.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK22612.2 - 1.2e-07 31.5 41.9 0.011 15.9 1.7 6.7 7 0 0 7 7 7 4 C2H2-type zinc finger DUF3505 PF12013.3 CBK22612.2 - 0.18 12.0 26.3 3.4 7.9 1.0 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF3505) RNA_pol_I_A49 PF06870.7 CBK22614.2 - 1.9e-07 30.0 3.9 3.3e-07 29.2 2.7 1.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor HMG_box PF00505.14 CBK22616.2 - 2.2e-49 165.6 27.4 8.2e-27 93.2 4.7 2.7 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CBK22616.2 - 1.8e-28 98.6 29.0 4e-15 55.9 4.7 2.8 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 CBK22616.2 - 8.1e-06 25.4 0.2 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain Tol_Tol_Ttg2 PF05494.7 CBK22616.2 - 2e-05 24.1 2.6 0.074 12.6 0.3 2.3 2 0 0 2 2 2 2 Toluene tolerance, Ttg2 YABBY PF04690.8 CBK22616.2 - 0.00012 22.3 0.8 0.00012 22.3 0.5 3.0 1 1 2 3 3 3 2 YABBY protein KfrA_N PF11740.3 CBK22616.2 - 0.0015 18.9 1.1 0.35 11.3 0.3 2.3 2 0 0 2 2 2 2 Plasmid replication region DNA-binding N-term DUF1014 PF06244.7 CBK22616.2 - 0.034 14.3 2.0 0.034 14.3 1.4 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1014) DUF399 PF04187.8 CBK22616.2 - 0.33 10.4 7.9 1.6 8.1 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF399 DUF2924 PF11149.3 CBK22616.2 - 1.1 9.2 11.6 2.1 8.3 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2924) CPSase_L_D2 PF02786.12 CBK22617.2 - 2.7e-72 242.4 0.0 4.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK22617.2 - 6.2e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK22617.2 - 7.8e-35 119.1 0.0 1.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK22617.2 - 2.8e-18 65.3 0.2 5.9e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK22617.2 - 1.8e-09 36.7 0.0 4.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK22617.2 - 3.8e-08 32.8 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK22617.2 - 4.5e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK22617.2 - 7.7e-08 31.9 0.1 3.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK22617.2 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK22617.2 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK22617.2 - 0.0024 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK22617.2 - 0.0037 16.9 0.4 0.012 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK22617.2 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK22617.2 - 0.015 15.6 0.0 0.46 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK22617.2 - 0.041 13.9 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK22617.2 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK22617.2 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK22617.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Vps5 PF09325.5 CBK22618.2 - 1.2e-23 83.6 1.6 3.1e-23 82.2 1.1 1.7 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CBK22618.2 - 2e-22 79.1 0.2 4.7e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.13 CBK22618.2 - 1.6e-08 34.3 6.2 1.6e-08 34.3 4.3 2.0 2 0 0 2 2 2 1 BAR domain INTS5_N PF14837.1 CBK22618.2 - 0.11 11.8 0.4 0.29 10.4 0.1 1.8 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Ribosomal_L1 PF00687.16 CBK22619.2 - 2.6e-46 157.7 7.5 3e-46 157.5 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family E1-E2_ATPase PF00122.15 CBK22620.2 - 3.1e-22 78.7 0.0 4.2e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 CBK22620.2 - 2.6e-05 23.5 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus GTP_EFTU PF00009.22 CBK22621.2 - 1.8e-56 190.5 0.0 2.5e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK22621.2 - 1.1e-33 115.3 0.1 3.2e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK22621.2 - 5.8e-10 39.1 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK22621.2 - 0.00011 22.1 0.1 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK22621.2 - 0.032 13.3 0.5 0.075 12.1 0.1 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK22621.2 - 0.042 14.3 0.4 0.64 10.5 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein HSP90 PF00183.13 CBK22622.2 - 2.6e-182 606.9 59.9 2.6e-182 606.9 41.5 2.7 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.21 CBK22622.2 - 6.2e-10 38.7 0.2 1.4e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK22622.2 - 1.9e-09 37.3 0.1 1.9e-09 37.3 0.1 3.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.5 CBK22622.2 - 0.01 14.3 4.9 0.022 13.2 1.8 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Diphthamide_syn PF01866.12 CBK22623.2 - 1.8e-41 142.4 0.0 2.9e-41 141.6 0.0 1.4 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Imm14 PF15428.1 CBK22624.2 - 0.031 14.6 2.4 0.031 14.6 1.7 1.8 1 1 0 1 1 1 0 Immunity protein 14 Fucose_iso_N2 PF07882.7 CBK22624.2 - 1.6 8.3 6.7 0.92 9.1 3.4 1.5 1 1 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF896 PF05979.7 CBK22624.2 - 1.8 8.1 9.3 6.6 6.4 0.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF896) BRO1 PF03097.13 CBK22625.2 - 2.2e-16 59.6 13.4 2.2e-16 59.6 9.3 1.8 2 0 0 2 2 2 1 BRO1-like domain FlaC_arch PF05377.6 CBK22625.2 - 0.028 14.3 8.3 2.2 8.2 0.0 6.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CBK22625.2 - 0.031 14.1 9.9 1.8 8.3 0.2 4.9 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 CBK22625.2 - 0.15 11.1 13.6 1.9 7.5 0.6 3.9 3 1 1 4 4 4 0 SF-assemblin/beta giardin UME PF08064.8 CBK22625.2 - 0.82 9.6 4.3 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 UME (NUC010) domain 6PGD PF00393.14 CBK22626.2 - 2.1e-114 381.6 0.0 2.7e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBK22626.2 - 4.2e-42 143.7 0.0 6.4e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBK22626.2 - 0.05 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 CBK22626.2 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1133 PF06576.6 CBK22626.2 - 0.12 11.5 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Rad51 PF08423.6 CBK22627.2 - 9.9e-22 77.0 0.0 1.2e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK22627.2 - 1e-10 41.3 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK22627.2 - 1.6e-06 27.4 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBK22627.2 - 0.00011 21.4 0.5 0.00029 20.0 0.3 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBK22627.2 - 0.00015 20.7 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain SPRY PF00622.23 CBK22628.2 - 2.8e-28 98.4 0.2 4.9e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Telomere_Sde2 PF13019.1 CBK22628.2 - 0.0041 16.8 0.1 0.0098 15.5 0.1 1.6 1 0 0 1 1 1 1 Telomere stability and silencing zf-CCCH PF00642.19 CBK22628.2 - 0.0081 15.8 2.3 0.0081 15.8 1.6 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HlyIII PF03006.15 CBK22629.2 - 1.6e-53 181.3 21.0 1.9e-53 181.1 14.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 CBK22629.2 - 1.6 8.6 7.9 0.82 9.5 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF962) HlyIII PF03006.15 CBK22630.2 - 1.7e-49 168.2 0.2 3.5e-49 167.2 0.1 1.5 1 1 0 1 1 1 1 Haemolysin-III related YejG PF13989.1 CBK22631.2 - 0.051 13.6 0.5 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 YejG-like protein Syntaxin_2 PF14523.1 CBK22631.2 - 0.06 13.3 0.4 0.06 13.3 0.3 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Seryl_tRNA_N PF02403.17 CBK22631.2 - 0.25 11.3 2.5 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Thioredoxin PF00085.15 CBK22632.2 - 2.1e-13 49.8 0.0 3.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBK22632.2 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain CTP_transf_1 PF01148.15 CBK22632.2 - 0.0051 16.4 2.1 0.0073 15.9 0.2 2.0 2 0 0 2 2 2 1 Cytidylyltransferase family Thioredoxin_2 PF13098.1 CBK22632.2 - 0.022 14.9 0.0 0.047 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Inositol_P PF00459.20 CBK22634.2 - 2.2e-55 187.8 0.1 2.7e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 CBK22634.2 - 0.027 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase zf-H2C2_2 PF13465.1 CBK22635.2 - 2.8e-20 71.5 24.6 8e-08 32.2 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBK22635.2 - 4.1e-08 33.0 27.4 0.021 15.1 1.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type CH PF00307.26 CBK22635.2 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CBK22635.2 - 0.045 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain UBA PF00627.26 CBK22637.2 - 2.4e-05 24.0 0.3 5.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain ING PF12998.2 CBK22637.2 - 0.002 18.3 0.1 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Amelogenin PF02948.10 CBK22637.2 - 0.038 14.6 1.5 0.067 13.8 1.1 1.3 1 0 0 1 1 1 0 Amelogenin NUDIX PF00293.23 CBK22638.2 - 2.8e-15 56.1 0.0 3.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 CBK22638.2 - 0.00066 19.0 0.0 0.00078 18.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase NTP_transf_2 PF01909.18 CBK22639.2 - 8.3e-09 35.6 0.0 1.7e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAZ_siRNAbind PF12212.3 CBK22641.2 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain Tmemb_161AB PF10268.4 CBK22642.2 - 9.2e-08 31.0 6.5 1.1e-07 30.8 4.5 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB ABC2_membrane_5 PF13346.1 CBK22642.2 - 0.002 17.4 8.9 0.002 17.4 6.2 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF1443 PF07280.6 CBK22642.2 - 0.5 9.9 9.1 0.06 12.9 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1443) DUF2254 PF10011.4 CBK22642.2 - 2.9 6.2 7.1 4.9 5.5 4.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Pkinase PF00069.20 CBK22644.2 - 6e-52 176.3 0.0 8.4e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22644.2 - 1.1e-30 106.5 1.5 3.2e-28 98.5 1.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22644.2 - 1.1e-07 31.1 0.1 1.1e-06 27.9 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBK22644.2 - 0.008 15.9 0.2 0.5 10.0 0.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBK22644.2 - 0.28 10.5 2.5 2.5 7.4 1.7 2.1 1 1 0 1 1 1 0 RIO1 family FHA PF00498.21 CBK22645.2 - 8e-18 64.3 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF4098 PF13345.1 CBK22648.2 - 0.00015 21.6 3.5 0.0078 16.1 0.6 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4098) adh_short PF00106.20 CBK22649.2 - 5.3e-26 91.5 0.0 6.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBK22649.2 - 8.3e-11 42.1 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBK22649.2 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBK22649.2 - 0.0032 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CBK22649.2 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.8 CBK22649.2 - 0.077 12.3 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DDE_Tnp_ISL3 PF01610.12 CBK22649.2 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase Polysacc_synt_2 PF02719.10 CBK22649.2 - 0.094 11.5 0.1 0.16 10.8 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ProRS-C_1 PF09180.6 CBK22649.2 - 0.11 12.4 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Ribosomal_L6 PF00347.18 CBK22650.2 - 1.5e-29 102.2 4.1 9.7e-15 54.8 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 CBK22651.2 - 3.6e-20 72.1 0.4 7.2e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBK22651.2 - 6.3e-13 47.9 0.4 6.3e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.7 CBK22651.2 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger PI3_PI4_kinase PF00454.22 CBK22652.2 - 3.7e-34 118.2 1.4 6.4e-34 117.4 1.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBK22652.2 - 2.4e-13 49.2 0.1 5.8e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 FATC domain EamA PF00892.15 CBK22653.2 - 1.1e-15 57.7 30.0 6.1e-11 42.4 5.9 3.2 1 1 2 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CBK22653.2 - 0.00017 21.7 10.1 0.00017 21.7 7.0 3.8 1 1 3 4 4 4 2 Multidrug resistance efflux transporter DUF606 PF04657.8 CBK22653.2 - 0.081 13.0 21.5 0.091 12.8 3.3 3.0 2 1 1 3 3 3 0 Protein of unknown function, DUF606 DUF2809 PF10990.3 CBK22653.2 - 4.2 7.8 13.5 0.2 12.1 2.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2809) LRR_6 PF13516.1 CBK22654.2 - 1.9e-17 61.3 14.6 0.00019 21.1 0.0 8.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 CBK22654.2 - 4.8e-10 38.8 16.7 0.0012 18.4 0.0 7.0 8 0 0 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK22654.2 - 0.00015 21.4 13.2 0.58 9.9 0.0 6.1 7 1 0 7 7 7 3 Leucine rich repeat LRR_7 PF13504.1 CBK22654.2 - 0.0071 16.3 8.0 5.9 7.5 0.0 6.8 8 0 0 8 8 8 1 Leucine rich repeat LRR_1 PF00560.28 CBK22654.2 - 0.055 13.5 19.1 1.2 9.4 0.0 8.1 9 2 1 10 10 10 0 Leucine Rich Repeat Peptidase_M17 PF00883.16 CBK22656.2 - 9.4e-98 326.9 0.0 1.1e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RNA_pol_Rpb2_6 PF00562.23 CBK22657.2 - 2.8e-123 411.4 0.0 4.1e-123 410.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBK22657.2 - 2.5e-40 137.6 0.1 3.9e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CBK22657.2 - 2.7e-35 121.5 0.0 6.8e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CBK22657.2 - 5.1e-29 100.3 0.0 1.5e-28 98.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CBK22657.2 - 3.7e-21 74.6 0.1 8.2e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 CBK22657.2 - 1.5e-14 53.5 3.2 1.3e-13 50.5 0.1 3.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 CBK22657.2 - 1.1e-13 50.9 1.1 2e-13 50.0 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 zf-C3HC4_2 PF13923.1 CBK22658.2 - 1.1e-09 38.1 10.4 2.2e-09 37.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22658.2 - 9.6e-09 34.7 8.6 1.7e-08 33.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CBK22658.2 - 5.3e-08 32.3 0.8 1.3e-07 31.0 0.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 CBK22658.2 - 6.7e-08 32.1 10.2 1.5e-07 30.9 7.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBK22658.2 - 1.3e-07 31.3 8.0 2.7e-07 30.2 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBK22658.2 - 1.8e-06 27.4 10.1 4.5e-06 26.2 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBK22658.2 - 2.9e-06 26.9 4.5 7e-06 25.6 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBK22658.2 - 9.9e-06 25.3 9.0 3.1e-05 23.7 6.2 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CBK22658.2 - 0.0011 18.4 4.7 0.0017 17.7 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.1 CBK22658.2 - 0.066 13.2 0.6 0.066 13.2 0.4 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-rbx1 PF12678.2 CBK22658.2 - 0.24 11.5 6.1 0.71 10.0 4.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE_2 PF02318.11 CBK22658.2 - 0.78 9.6 8.5 0.75 9.7 4.8 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Cript PF10235.4 CBK22658.2 - 1.6 9.1 10.5 0.036 14.4 2.4 1.9 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT CDP-OH_P_transf PF01066.16 CBK22659.2 - 2.4e-18 66.2 11.5 5.7e-18 65.0 8.0 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase GILT PF03227.11 CBK22660.2 - 4e-75 248.6 8.7 2.3e-24 85.3 0.2 3.2 3 0 0 3 3 3 3 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.1 CBK22660.2 - 2.4e-05 24.4 4.0 5.7 6.9 0.1 5.3 3 3 0 3 3 3 3 Thioredoxin Galactosyl_T PF01762.16 CBK22660.2 - 0.0034 17.0 0.2 5 6.6 0.0 3.1 3 0 0 3 3 3 2 Galactosyltransferase DUF1392 PF07154.6 CBK22660.2 - 0.024 14.5 0.0 57 3.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1392) BOP1NT PF08145.7 CBK22660.2 - 0.067 12.9 0.1 10 5.7 0.0 2.7 3 0 0 3 3 3 0 BOP1NT (NUC169) domain GST_N_3 PF13417.1 CBK22660.2 - 0.1 12.8 0.0 91 3.3 0.0 3.4 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain DUF1438 PF07270.6 CBK22660.2 - 0.13 12.1 8.2 16 5.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) RE_Bpu10I PF09549.5 CBK22660.2 - 0.26 10.8 2.6 20 4.6 0.0 2.9 3 0 0 3 3 3 0 Bpu10I restriction endonuclease Peptidase_C13 PF01650.13 CBK22661.2 - 3.5e-50 170.7 0.0 6.9e-50 169.7 0.0 1.4 2 0 0 2 2 2 1 Peptidase C13 family DUF1307 PF06998.6 CBK22661.2 - 0.23 11.5 1.4 0.42 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) PEPCK_ATP PF01293.15 CBK22662.2 - 4.9e-211 701.2 0.0 5.7e-211 701.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK PF00821.13 CBK22662.2 - 0.031 12.4 0.1 0.2 9.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 CBK22662.2 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.18 CBK22663.2 - 2.7e-62 210.2 0.1 4.1e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK22663.2 - 8.9e-16 57.5 0.1 2.8e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22663.2 - 6.2e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK22663.2 - 0.00011 22.1 0.0 0.00092 19.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBK22663.2 - 0.00065 18.6 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Serglycin PF04360.7 CBK22663.2 - 0.0076 15.9 1.2 0.015 15.0 0.8 1.4 1 0 0 1 1 1 1 Serglycin DUF3246 PF11596.3 CBK22663.2 - 1.4 8.1 3.5 2.2 7.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) EMP24_GP25L PF01105.19 CBK22664.2 - 1.1e-28 100.1 2.9 1.3e-28 100.0 2.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FtsK_SpoIIIE_N PF12538.3 CBK22664.2 - 0.065 13.3 0.5 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 DNA transporter WEMBL PF05701.6 CBK22664.2 - 0.088 11.2 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TAA-Trp-ring PF15401.1 CBK22664.2 - 0.34 11.1 3.0 0.39 10.9 0.6 2.0 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin AhpC-TSA PF00578.16 CBK22665.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK22665.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK22665.2 - 2.2e-12 46.4 0.0 4.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin HA2 PF04408.18 CBK22666.2 - 6.2e-27 93.6 0.0 1.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK22666.2 - 2.8e-26 91.5 0.0 8.4e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK22666.2 - 6.9e-14 51.4 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22666.2 - 3.1e-07 30.0 0.1 7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CBK22666.2 - 1.2e-05 24.3 0.0 2.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBK22666.2 - 0.0002 21.4 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBK22666.2 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBK22666.2 - 0.0035 17.0 0.0 0.009 15.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBK22666.2 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK22666.2 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HAD_2 PF13419.1 CBK22666.2 - 0.036 14.2 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NB-ARC PF00931.17 CBK22666.2 - 0.058 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 CBK22666.2 - 0.06 13.1 0.0 2.9 7.6 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CBK22666.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBK22666.2 - 0.1 12.5 0.1 2.2 8.1 0.1 2.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK22666.2 - 0.11 12.7 0.2 3.4 7.9 0.1 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CBK22666.2 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CBK22666.2 - 0.14 11.8 0.1 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 NACHT domain CTP_synth_N PF06418.9 CBK22667.2 - 4.5e-125 416.2 0.0 6e-125 415.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CBK22667.2 - 2e-48 164.3 0.0 3.4e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBK22667.2 - 2.8e-09 36.7 0.2 7.8e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CBK22667.2 - 5.3e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2726 PF10881.3 CBK22667.2 - 0.094 12.3 0.0 0.29 10.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2726) Spectrin PF00435.16 CBK22668.2 - 0.017 15.3 0.4 0.035 14.3 0.3 1.4 1 0 0 1 1 1 0 Spectrin repeat CHASE3 PF05227.8 CBK22668.2 - 0.043 13.4 0.1 0.066 12.8 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain zf-CCHC_3 PF13917.1 CBK22669.2 - 6.9e-16 57.7 5.5 1.3e-15 56.8 3.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Zn_ribbon_2 PF12674.2 CBK22669.2 - 0.0093 16.2 1.2 0.023 15.0 0.2 2.0 2 0 0 2 2 2 1 Putative zinc ribbon domain zf-C4pol PF14260.1 CBK22669.2 - 0.025 14.5 0.7 0.064 13.2 0.5 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Phospholip_B PF04916.8 CBK22670.2 - 1.8e-121 405.9 3.2 2.2e-121 405.6 2.2 1.0 1 0 0 1 1 1 1 Phospholipase B Helicase_C PF00271.26 CBK22671.2 - 5.6e-16 58.1 0.0 7.9e-07 28.8 0.0 3.3 3 0 0 3 3 3 3 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22671.2 - 1e-12 47.8 0.0 7e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase GHMP_kinases_C PF08544.8 CBK22671.2 - 0.098 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal Smr PF01713.16 CBK22672.2 - 4.3e-08 33.2 0.0 8.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Smr domain Pribosyltran_N PF13793.1 CBK22673.2 - 6.6e-41 138.6 0.0 1.1e-38 131.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBK22673.2 - 4.4e-22 78.7 0.6 8.5e-22 77.7 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBK22673.2 - 1.9e-05 24.3 0.6 0.00018 21.1 0.1 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBK22673.2 - 0.017 14.3 0.1 0.034 13.3 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GYF PF02213.11 CBK22674.2 - 4.1e-06 26.2 0.1 6.6e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 GYF domain GCIP PF13324.1 CBK22674.2 - 0.1 11.8 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Abhydrolase_5 PF12695.2 CBK22675.2 - 6.6e-06 25.9 0.0 8.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBK22675.2 - 0.0012 18.8 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CBK22675.2 - 0.0029 17.0 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CBK22675.2 - 0.0036 16.5 0.0 0.0048 16.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 CBK22675.2 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CBK22675.2 - 0.033 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LRR_7 PF13504.1 CBK22677.2 - 0.089 13.0 10.6 27 5.5 0.1 4.9 5 0 0 5 5 5 0 Leucine rich repeat IncA PF04156.9 CBK22678.2 - 0.0015 18.1 8.4 0.0015 18.1 5.9 8.0 3 3 3 7 7 7 3 IncA protein DUF972 PF06156.8 CBK22678.2 - 0.011 16.0 6.9 0.011 16.0 4.8 9.2 5 2 3 8 8 8 0 Protein of unknown function (DUF972) IncA PF04156.9 CBK22679.2 - 0.00024 20.7 242.4 0.032 13.8 16.8 8.4 1 1 7 8 8 8 5 IncA protein AAA_13 PF13166.1 CBK22679.2 - 0.27 9.6 188.7 0.022 13.2 24.1 6.8 1 1 4 5 5 5 0 AAA domain E1_DerP2_DerF2 PF02221.10 CBK22680.2 - 0.00011 22.4 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 ML domain Herpes_pp38 PF04846.8 CBK22682.2 - 0.021 14.1 0.2 0.042 13.1 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein B3_4 PF03483.12 CBK22684.2 - 7.7e-20 71.0 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CBK22684.2 - 6.8e-13 48.2 0.0 6.6e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 CBK22684.2 - 0.088 11.9 0.1 7.4 5.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) LRR_6 PF13516.1 CBK22685.2 - 7e-08 31.7 7.8 0.00052 19.8 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CBK22685.2 - 0.00078 19.0 2.6 0.00078 19.0 1.8 3.9 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBK22685.2 - 0.22 11.8 13.4 0.89 10.0 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 CBK22685.2 - 0.25 11.5 16.2 2.9 8.2 0.1 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat HAD_2 PF13419.1 CBK22688.2 - 1.6e-19 70.8 0.0 2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBK22688.2 - 5.8e-08 32.3 0.0 1.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBK22688.2 - 5.2e-06 27.0 0.0 0.004 17.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK22688.2 - 0.0013 18.9 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Y_phosphatase3 PF13350.1 CBK22689.2 - 0.00052 20.2 0.0 0.00085 19.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBK22689.2 - 0.051 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.9 CBK22689.2 - 0.073 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.15 CBK22689.2 - 0.087 12.4 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain IpgD PF05925.7 CBK22689.2 - 0.095 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Proteasome PF00227.21 CBK22690.2 - 3.9e-49 166.5 0.1 4.7e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Skp1_POZ PF03931.10 CBK22691.2 - 4e-11 42.8 1.2 6.6e-11 42.1 0.8 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 CBK22691.2 - 6.5e-09 35.7 0.7 1.4e-08 34.6 0.5 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Glyco_transf_49 PF13896.1 CBK22692.2 - 1.3e-05 24.5 0.6 1.5e-05 24.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_hydro_35 PF01301.14 CBK22693.2 - 1e-109 366.7 0.9 1.7e-109 366.0 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBK22693.2 - 4.3e-18 65.5 0.1 3.8e-16 59.1 0.0 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 CBK22693.2 - 4.8e-05 23.5 0.1 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.13 CBK22693.2 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HSP70 PF00012.15 CBK22694.2 - 4.7e-46 156.9 2.3 5.7e-46 156.6 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22694.2 - 8.4e-11 41.0 0.1 9.1e-09 34.3 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein StbA PF06406.6 CBK22694.2 - 0.003 16.5 0.1 0.0085 15.0 0.0 1.8 2 1 0 2 2 2 1 StbA protein Hexokinase_1 PF00349.16 CBK22694.2 - 0.0037 16.6 1.0 0.12 11.6 0.0 2.7 2 1 1 3 3 3 1 Hexokinase FtsA PF14450.1 CBK22694.2 - 0.0065 16.3 5.7 0.015 15.0 2.4 2.5 2 2 0 2 2 2 1 Cell division protein FtsA Hydantoinase_A PF01968.13 CBK22694.2 - 0.039 13.0 0.5 0.54 9.2 0.0 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase YqzH PF14164.1 CBK22694.2 - 0.099 12.5 0.5 0.25 11.2 0.3 1.6 1 0 0 1 1 1 0 YqzH-like protein BRCT PF00533.21 CBK22695.2 - 1e-10 41.6 0.0 2.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pescadillo_N PF06732.6 CBK22696.2 - 1.1e-104 349.6 1.0 1.7e-104 349.0 0.7 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus AMP-binding PF00501.23 CBK22696.2 - 4.2e-73 246.1 0.0 7.3e-73 245.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme FAM60A PF15396.1 CBK22697.2 - 1.6 8.4 8.4 1.9 8.2 5.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 CBK22697.2 - 5.6 4.8 17.1 6.4 4.6 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein EF-hand_1 PF00036.27 CBK22698.2 - 1.9e-11 42.3 0.0 0.00029 19.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBK22698.2 - 5.5e-11 42.4 0.4 1.7e-10 40.8 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.2 CBK22698.2 - 3.7e-09 36.2 0.0 9.9e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 CBK22698.2 - 4.2e-09 35.5 0.1 0.0028 17.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBK22698.2 - 4.5e-09 35.2 0.0 0.0023 17.1 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBK22698.2 - 2.3e-06 27.1 1.8 0.005 16.4 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBK22698.2 - 0.00028 20.8 0.0 0.00028 20.8 0.0 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF812 PF05667.6 CBK22698.2 - 0.005 15.4 4.3 0.0067 14.9 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DivIC PF04977.10 CBK22698.2 - 0.027 13.9 9.1 0.093 12.2 6.3 1.9 1 0 0 1 1 1 0 Septum formation initiator Cauli_AT PF03233.8 CBK22698.2 - 0.048 13.3 3.3 0.084 12.5 2.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein End3 PF12761.2 CBK22698.2 - 0.33 10.5 9.6 16 5.0 5.0 2.5 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 MFS_1 PF07690.11 CBK22699.2 - 4.6e-13 48.6 2.2 2.8e-12 46.0 1.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CBK22699.2 - 0.0069 14.4 0.1 0.014 13.4 0.0 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRIQK PF15168.1 CBK22699.2 - 6.5 6.7 8.6 1.4 8.9 1.7 2.8 2 1 1 3 3 3 0 Triple QxxK/R motif-containing protein family WBP-1 PF11669.3 CBK22700.2 - 0.092 12.8 1.2 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Transcrip_act PF04949.8 CBK22701.2 - 7.9e-10 38.5 18.7 5.2e-09 35.9 11.3 2.2 1 1 1 2 2 2 1 Transcriptional activator Phasin PF05597.6 CBK22701.2 - 0.0042 16.8 6.5 0.0042 16.8 4.5 2.4 1 1 2 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4200 PF13863.1 CBK22701.2 - 0.0054 16.6 16.2 0.0054 16.6 11.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Rnk_N PF14760.1 CBK22701.2 - 0.011 15.7 3.2 0.21 11.7 0.1 3.2 3 0 0 3 3 3 0 Rnk N-terminus Reo_sigmaC PF04582.7 CBK22701.2 - 0.43 9.7 3.5 0.27 10.3 1.1 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF763 PF05559.6 CBK22701.2 - 0.48 9.3 4.7 0.67 8.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Laminin_II PF06009.7 CBK22701.2 - 0.74 9.5 14.6 0.054 13.2 4.5 2.6 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 CBK22701.2 - 1.1 9.1 10.5 0.32 10.8 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CBK22701.2 - 1.1 9.0 31.2 0.036 13.9 6.5 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Late_protein_L2 PF00513.13 CBK22701.2 - 4 6.1 6.6 2.1 7.1 2.3 1.8 1 1 1 2 2 2 0 Late Protein L2 COG2 PF06148.6 CBK22701.2 - 6.4 6.6 12.1 14 5.5 4.9 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CBK22701.2 - 7.7 6.0 26.6 1e+02 2.3 0.9 2.5 1 1 1 2 2 2 0 IncA protein PhoU_div PF01865.11 CBK22702.2 - 0.0025 17.0 2.4 0.31 10.1 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function DUF47 DUF912 PF06024.7 CBK22702.2 - 0.011 15.7 1.4 0.011 15.7 1.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAH PF02671.16 CBK22702.2 - 1 9.0 6.4 1.9 8.1 1.0 2.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat UPF0118 PF01594.11 CBK22702.2 - 1.7 7.5 3.4 0.74 8.7 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF20 DUF2023 PF09633.5 CBK22703.2 - 0.06 13.2 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) DUF3798 PF12683.2 CBK22703.2 - 0.096 11.7 0.2 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) RRM_2 PF04059.7 CBK22705.2 - 4.3e-20 71.5 0.1 5.7e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 DWNN PF08783.6 CBK22706.2 - 4.6e-11 42.4 0.1 8.2e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 CBK22706.2 - 0.00045 19.6 3.3 0.00045 19.6 2.3 2.0 3 0 0 3 3 3 1 Zinc knuckle LsmAD PF06741.8 CBK22707.2 - 7.2e-06 26.0 0.0 7.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 LsmAD domain Collagen PF01391.13 CBK22707.2 - 0.0038 16.7 4.5 0.0038 16.7 3.1 2.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Adeno_terminal PF02459.10 CBK22707.2 - 3.5 5.6 11.2 4.5 5.3 7.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Ank_2 PF12796.2 CBK22708.2 - 7.1e-34 116.0 9.5 1.7e-15 57.0 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBK22708.2 - 1.1e-28 99.0 12.7 1.2e-12 47.9 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBK22708.2 - 2.7e-26 90.0 7.9 3.2e-07 29.8 0.0 5.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 CBK22708.2 - 1.1e-24 85.8 16.1 4.1e-09 36.3 0.4 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK22708.2 - 9.4e-22 74.9 2.5 5.6e-05 22.9 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat GLTP PF08718.6 CBK22709.2 - 8.6e-27 94.0 0.2 1.6e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) E1_DerP2_DerF2 PF02221.10 CBK22710.2 - 0.026 14.7 0.4 1 9.6 0.1 2.2 2 0 0 2 2 2 0 ML domain HCaRG PF07258.9 CBK22711.2 - 3.6e-06 26.6 0.0 4.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 HCaRG protein DNA_pol_E_B PF04042.11 CBK22712.2 - 4e-25 88.3 0.3 4.9e-25 88.0 0.2 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B He_PIG PF05345.7 CBK22715.2 - 1.1e-27 95.7 42.5 7.2e-06 25.9 0.7 7.5 7 0 0 7 7 7 6 Putative Ig domain I-set PF07679.11 CBK22715.2 - 0.0014 18.4 5.2 4.9 7.0 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain IncA PF04156.9 CBK22715.2 - 0.038 13.5 0.2 0.06 12.9 0.2 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK22715.2 - 0.16 11.9 12.4 1.2 9.2 0.1 4.7 5 0 0 5 5 5 0 Hormone receptor domain hEGF PF12661.2 CBK22715.2 - 1.7 8.9 5.4 29 5.0 0.1 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF Thg1C PF14413.1 CBK22716.2 - 2.6e-45 153.0 0.2 4.3e-45 152.3 0.1 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 CBK22716.2 - 1.9e-42 144.0 0.2 2.9e-42 143.4 0.2 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 CBK22717.2 - 3.8e-37 124.8 6.3 6.8e-07 28.9 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBK22717.2 - 0.012 15.3 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cystatin PF00031.16 CBK22718.2 - 1.8e-10 40.7 0.2 2.2e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Cystatin domain Rota_NS53 PF00981.12 CBK22718.2 - 0.037 12.6 0.2 0.04 12.5 0.1 1.0 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) MCP_N PF05581.7 CBK22718.2 - 0.056 13.5 0.1 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Vibrio chemotaxis protein N terminus UPF0016 PF01169.14 CBK22718.2 - 0.068 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 AARP2CN PF08142.7 CBK22719.2 - 8e-26 89.3 0.3 6e-25 86.5 0.0 2.7 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CBK22719.2 - 1.4e-07 31.0 0.0 5.2e-05 22.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBK22719.2 - 6.2e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CBK22719.2 - 0.00085 19.0 0.5 0.0025 17.5 0.4 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBK22719.2 - 0.001 18.9 0.1 0.0028 17.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CBK22719.2 - 0.002 17.6 0.0 0.0049 16.3 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBK22719.2 - 0.0023 17.8 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBK22719.2 - 0.0027 17.7 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBK22719.2 - 0.0061 16.7 0.4 0.015 15.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBK22719.2 - 0.0082 15.8 1.2 0.023 14.4 0.5 2.0 2 0 0 2 2 2 1 NTPase Miro PF08477.8 CBK22719.2 - 0.0097 16.3 0.0 0.0097 16.3 0.0 2.3 2 0 0 2 2 1 1 Miro-like protein AAA_25 PF13481.1 CBK22719.2 - 0.014 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBK22719.2 - 0.026 14.7 0.0 0.093 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 CBK22719.2 - 0.059 14.1 0.0 0.059 14.1 0.0 3.9 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.22 CBK22719.2 - 0.56 10.4 0.0 0.56 10.4 0.0 2.6 2 1 0 2 2 1 0 ABC transporter F_actin_cap_B PF01115.12 CBK22720.2 - 1.7e-70 236.9 0.2 2e-70 236.7 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 CBK22720.2 - 0.00011 21.4 0.7 0.00021 20.4 0.5 1.6 1 1 0 1 1 1 1 F-actin capping protein alpha subunit ABC_transp_aux PF09822.4 CBK22720.2 - 0.0048 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Peptidase_C13 PF01650.13 CBK22721.2 - 4.8e-49 166.9 0.1 7.7e-49 166.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family HTH_24 PF13412.1 CBK22721.2 - 0.029 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SopD PF11047.3 CBK22722.2 - 0.099 11.5 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Salmonella outer protein D ABC_tran PF00005.22 CBK22723.2 - 1.3e-29 103.2 0.0 2.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK22723.2 - 7.5e-11 42.5 1.3 6.2e-07 29.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBK22723.2 - 0.00034 19.9 0.6 0.2 10.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBK22723.2 - 0.00038 20.5 0.4 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK22723.2 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA12 PF10443.4 CBK22723.2 - 0.0026 16.3 0.0 0.0037 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein SbcCD_C PF13558.1 CBK22723.2 - 0.004 17.0 0.1 0.049 13.5 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBK22723.2 - 0.02 14.4 0.1 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CBK22723.2 - 0.031 13.9 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 CBK22723.2 - 0.032 15.0 0.6 0.12 13.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK22723.2 - 0.037 12.9 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 CBK22723.2 - 0.038 13.1 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CBK22723.2 - 0.068 13.0 0.1 0.18 11.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK22723.2 - 0.079 12.3 0.1 3 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 CBK22723.2 - 0.1 11.9 0.3 0.9 8.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBK22723.2 - 0.11 12.6 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CBK22723.2 - 0.15 12.3 2.8 0.29 11.4 1.9 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBK22723.2 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Syntaxin PF00804.20 CBK22724.2 - 7.1e-09 35.7 4.7 1e-08 35.2 3.3 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin-6_N PF09177.6 CBK22724.2 - 0.0021 18.4 3.9 0.003 17.9 1.7 1.8 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SPO22 PF08631.5 CBK22724.2 - 0.026 13.5 0.9 0.032 13.3 0.6 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Spc7 PF08317.6 CBK22724.2 - 0.19 10.3 5.5 0.25 9.9 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 CBK22724.2 - 1.9 7.6 7.2 0.4 9.8 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) Syntaxin_2 PF14523.1 CBK22724.2 - 4.8 7.2 8.6 7.6 6.6 3.9 2.4 1 1 1 2 2 2 0 Syntaxin-like protein AcetylCoA_hyd_C PF13336.1 CBK22725.2 - 2.1e-62 209.3 0.0 3.2e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 CBK22725.2 - 7.6e-21 74.7 0.0 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain polyprenyl_synt PF00348.12 CBK22726.2 - 1.7e-54 184.4 0.0 2.2e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Thioredoxin PF00085.15 CBK22727.2 - 1.1e-38 131.0 0.0 2.5e-27 94.5 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CBK22727.2 - 9.5e-28 97.2 4.5 1.9e-20 73.4 0.3 3.5 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK22727.2 - 3.1e-13 49.8 0.6 8.2e-10 38.8 0.0 3.7 2 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK22727.2 - 2e-07 30.9 0.0 1.8e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 CBK22727.2 - 0.0001 21.9 0.3 0.079 12.6 0.0 3.1 2 1 2 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CBK22727.2 - 0.00097 18.7 0.1 0.56 9.7 0.0 2.9 3 0 0 3 3 3 2 Redoxin Thioredoxin_8 PF13905.1 CBK22727.2 - 0.0027 17.7 1.7 0.073 13.1 0.1 3.7 4 1 1 5 5 5 1 Thioredoxin-like Nucleoplasmin PF03066.10 CBK22727.2 - 0.14 11.7 6.3 0.45 10.0 4.5 1.8 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 CBK22727.2 - 4.5 7.4 10.8 11 6.2 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 CBK22727.2 - 5.5 7.3 11.3 11 6.4 7.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM PF00493.18 CBK22729.2 - 3e-129 430.5 0.0 4.2e-129 430.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBK22729.2 - 6.6e-13 49.2 0.2 1.5e-12 48.0 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBK22729.2 - 7.4e-07 28.5 0.1 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TPR_11 PF13414.1 CBK22729.2 - 2.4e-06 27.1 0.4 6.3e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 TPR repeat AAA_5 PF07728.9 CBK22729.2 - 3.8e-05 23.4 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TPR_2 PF07719.12 CBK22729.2 - 0.0026 17.5 0.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Sigma54_activat PF00158.21 CBK22729.2 - 0.0098 15.3 0.0 0.56 9.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 CBK22729.2 - 0.021 15.1 0.7 0.07 13.5 0.5 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBK22729.2 - 0.044 13.3 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBK22729.2 - 0.12 12.6 0.1 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Metallophos PF00149.23 CBK22730.2 - 1.9e-31 109.0 0.0 3.5e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CBK22730.2 - 4.9e-17 61.7 0.7 2.2e-16 59.6 0.5 2.1 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 CBK22730.2 - 2e-10 39.8 0.5 5e-09 35.3 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK22730.2 - 3.8e-09 35.7 0.2 3.4e-08 32.7 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK22730.2 - 1.3e-06 27.9 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 CBK22730.2 - 1.1e-05 24.7 0.1 2.9e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK22730.2 - 0.004 17.5 0.2 0.0089 16.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK22730.2 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBK22730.2 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBK22730.2 - 0.023 13.9 0.0 0.056 12.6 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR Fis1_TPR_C PF14853.1 CBK22730.2 - 0.041 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CBK22730.2 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBK22730.2 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK22730.2 - 0.15 12.7 0.1 0.4 11.4 0.0 1.7 2 0 0 2 2 1 0 Tetratricopeptide repeat PEPCK_ATP PF01293.15 CBK22731.2 - 4.6e-211 701.3 0.0 5.4e-211 701.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK PF00821.13 CBK22731.2 - 0.03 12.5 0.1 0.2 9.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 CBK22731.2 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SAM_2 PF07647.12 CBK22732.2 - 2.6e-08 33.5 1.0 1.7e-06 27.7 0.0 2.6 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CBK22732.2 - 2.5e-06 27.5 1.7 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FKBP_N PF01346.13 CBK22732.2 - 0.057 13.4 0.1 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HHH_5 PF14520.1 CBK22732.2 - 0.068 13.3 0.0 1.9 8.7 0.0 2.7 2 1 0 2 2 2 0 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 CBK22732.2 - 0.1 12.0 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain NCD1 PF04904.8 CBK22732.2 - 0.13 12.0 0.2 3.3 7.5 0.0 2.4 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) Ank PF00023.25 CBK22733.2 - 6.8e-31 104.5 0.1 1.6e-09 37.0 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CBK22733.2 - 4.5e-27 94.2 0.1 2.2e-16 59.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBK22733.2 - 4.1e-22 76.0 1.3 7.3e-06 25.7 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBK22733.2 - 4.4e-21 74.4 1.2 1.7e-07 31.2 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBK22733.2 - 7.6e-16 58.1 0.2 1.3e-07 31.8 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Methyltransf_8 PF05148.10 CBK22733.2 - 0.018 14.6 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase L51_S25_CI-B8 PF05047.11 CBK22735.2 - 6.1e-10 38.6 0.0 8.4e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ERGIC_N PF13850.1 CBK22736.2 - 2.5e-23 81.8 2.0 5.2e-23 80.8 1.4 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.15 CBK22736.2 - 7.6e-19 67.3 0.0 1.3e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBK22736.2 - 7e-06 25.9 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like COPIIcoated_ERV PF07970.7 CBK22736.2 - 0.0001 22.0 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredox_DsbH PF03190.10 CBK22736.2 - 0.00028 20.6 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 CBK22736.2 - 0.0031 17.6 0.0 0.007 16.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK22736.2 - 0.0088 16.1 0.1 0.037 14.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like RCC1 PF00415.13 CBK22737.2 - 9.6e-71 233.8 14.5 4.4e-16 58.8 0.0 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK22737.2 - 8.9e-42 139.8 29.6 2.4e-09 36.5 0.5 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 CBK22737.2 - 0.024 14.4 0.5 21 4.8 0.0 4.2 4 1 0 5 5 5 0 SUKH-3 immunity protein GAD-like PF08887.6 CBK22737.2 - 0.08 13.0 0.0 0.92 9.6 0.0 2.4 2 0 0 2 2 2 0 GAD-like domain YL1 PF05764.8 CBK22738.2 - 0.026 14.1 5.0 0.025 14.1 3.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Kdo PF06293.9 CBK22738.2 - 0.054 12.5 0.1 0.057 12.4 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps52 PF04129.7 CBK22739.2 - 1.7e-40 139.0 1.1 1.7e-40 139.0 0.8 2.1 1 1 1 2 2 2 1 Vps52 / Sac2 family Cytochrom_B562 PF07361.6 CBK22739.2 - 0.048 14.0 8.2 0.78 10.1 1.1 2.9 3 0 0 3 3 3 0 Cytochrome b562 Pyridox_oxase_2 PF12766.2 CBK22739.2 - 0.12 12.6 0.1 0.61 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Toxin_ToxA PF11584.3 CBK22739.2 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA PHD PF00628.24 CBK22740.2 - 1.4e-06 27.8 12.5 1.8e-05 24.3 8.6 2.4 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK22740.2 - 0.013 14.8 0.6 0.013 14.8 0.4 2.5 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 CBK22740.2 - 0.028 13.6 3.2 0.036 13.3 1.1 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_3 PF13922.1 CBK22740.2 - 0.81 9.9 4.6 0.23 11.7 0.3 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_2 PF13639.1 CBK22740.2 - 1.7 8.5 7.0 3.6 7.5 4.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 CBK22741.2 - 2.3e-23 82.2 5.2 4.6e-23 81.3 3.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBK22741.2 - 3.7e-20 71.8 1.8 3.7e-20 71.8 1.2 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Trehalose_PPase PF02358.11 CBK22741.2 - 0.088 11.7 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase zf-MIZ PF02891.15 CBK22742.2 - 1.9e-14 52.8 0.6 3e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBK22742.2 - 1.9e-06 27.2 1.3 3.3e-06 26.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pribosyltran_N PF13793.1 CBK22743.2 - 2.5e-36 123.9 0.2 1.1e-35 121.8 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBK22743.2 - 3.5e-15 56.2 0.1 6.2e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBK22743.2 - 7.7e-07 28.8 0.0 4.1e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Cation_efflux PF01545.16 CBK22744.2 - 2.7e-56 190.7 4.9 3.3e-56 190.4 3.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1449 PF07290.6 CBK22744.2 - 0.0035 16.7 0.5 0.0061 15.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1449) Peptidase_C1 PF00112.18 CBK22745.2 - 1.1e-55 188.9 9.5 1.4e-55 188.6 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Reprolysin_5 PF13688.1 CBK22746.2 - 2.4e-06 27.6 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Shisa PF13908.1 CBK22746.2 - 9.1e-06 25.9 2.7 2e-05 24.8 1.9 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Reprolysin_2 PF13574.1 CBK22746.2 - 9e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CBK22746.2 - 0.00018 22.0 0.0 0.00051 20.5 0.0 1.8 2 0 0 2 2 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CBK22746.2 - 0.0019 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CBK22746.2 - 0.0026 17.4 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Rhabdo_glycop PF00974.13 CBK22746.2 - 0.14 10.3 0.1 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein ODV-E18 PF10717.4 CBK22746.2 - 0.2 11.0 0.8 0.45 9.9 0.5 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Rifin_STEVOR PF02009.11 CBK22746.2 - 0.22 11.1 0.7 0.42 10.2 0.5 1.3 1 0 0 1 1 1 0 Rifin/stevor family RELT PF12606.3 CBK22746.2 - 0.35 10.0 8.1 0.89 8.7 5.6 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF2668 PF10873.3 CBK22746.2 - 0.38 10.9 3.0 0.88 9.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF912 PF06024.7 CBK22746.2 - 1.8 8.6 3.8 1.2 9.1 0.1 2.4 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HSP70 PF00012.15 CBK22748.2 - 2.8e-87 293.0 0.4 3.4e-87 292.7 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22748.2 - 1.3e-11 43.6 0.1 2.2e-05 23.2 0.0 3.3 2 1 0 3 3 3 3 MreB/Mbl protein StbA PF06406.6 CBK22748.2 - 0.045 12.6 0.0 0.36 9.7 0.0 2.2 1 1 1 2 2 2 0 StbA protein DDR PF08841.5 CBK22748.2 - 0.069 11.9 0.1 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CBK22748.2 - 0.13 12.1 3.4 4.3 7.1 0.2 3.0 3 0 0 3 3 3 0 Cell division protein FtsA RNA_pol_A_bac PF01000.21 CBK22749.2 - 2e-21 76.2 0.0 5.3e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBK22749.2 - 1.7e-13 49.4 0.0 2.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 CBK22749.2 - 0.0011 19.3 0.6 0.0024 18.2 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK22749.2 - 0.0076 16.4 1.4 0.016 15.4 1.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF22 PF01629.11 CBK22749.2 - 0.047 13.1 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF22 Fer4 PF00037.22 CBK22749.2 - 0.16 11.6 2.2 0.19 11.3 0.5 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_5 PF07728.9 CBK22750.2 - 3.3e-125 412.4 0.0 5.6e-22 77.9 0.0 10.0 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBK22750.2 - 7.1e-32 109.7 0.0 8.3e-10 38.3 0.0 8.9 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBK22750.2 - 5.4e-25 88.1 0.0 8e-05 22.8 0.0 7.5 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK22750.2 - 6.5e-23 81.6 6.7 0.001 19.0 0.0 9.1 8 0 0 8 8 8 5 AAA ATPase domain AAA_22 PF13401.1 CBK22750.2 - 8e-21 74.5 0.3 0.059 13.5 0.0 8.0 6 1 0 6 6 6 5 AAA domain T2SE PF00437.15 CBK22750.2 - 1.4e-16 60.2 0.0 0.027 13.3 0.0 7.1 7 0 0 7 7 7 5 Type II/IV secretion system protein Zeta_toxin PF06414.7 CBK22750.2 - 6e-16 58.1 0.0 0.14 11.2 0.0 6.7 6 0 0 6 6 6 5 Zeta toxin AAA_33 PF13671.1 CBK22750.2 - 1.2e-15 57.6 0.1 0.097 12.5 0.0 7.9 8 0 0 8 8 7 3 AAA domain Sigma54_activ_2 PF14532.1 CBK22750.2 - 5.3e-15 55.6 0.3 0.11 12.4 0.0 8.0 7 1 1 8 8 7 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 CBK22750.2 - 7.7e-15 54.7 0.1 0.059 12.8 0.1 6.7 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_19 PF13245.1 CBK22750.2 - 2e-14 53.0 0.4 0.028 14.1 0.1 6.5 7 0 0 7 7 6 3 Part of AAA domain NACHT PF05729.7 CBK22750.2 - 6.9e-14 51.8 2.9 0.15 11.7 0.0 7.0 7 0 0 7 7 6 4 NACHT domain AAA_29 PF13555.1 CBK22750.2 - 4.2e-13 48.6 0.2 0.025 14.0 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK22750.2 - 1.5e-12 48.3 15.4 0.65 10.8 0.0 9.1 7 1 0 7 7 6 3 AAA domain RNA_helicase PF00910.17 CBK22750.2 - 1.5e-11 44.4 0.5 1.2 9.3 0.0 6.7 6 0 0 6 6 6 2 RNA helicase ABC_tran PF00005.22 CBK22750.2 - 5.9e-11 42.8 23.1 0.0064 16.7 0.0 8.8 8 0 0 8 8 6 3 ABC transporter UPF0079 PF02367.12 CBK22750.2 - 2.1e-09 37.0 1.5 1.5 8.4 0.0 5.8 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CBK22750.2 - 4.4e-09 36.2 0.1 0.011 15.2 0.0 5.6 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase Miro PF08477.8 CBK22750.2 - 1.3e-08 35.3 0.3 4.4 7.8 0.0 7.3 6 0 0 6 6 6 1 Miro-like protein IstB_IS21 PF01695.12 CBK22750.2 - 3e-08 33.2 0.0 0.99 8.7 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.7 CBK22750.2 - 3.5e-07 29.5 1.3 0.33 9.9 0.0 6.0 7 0 0 7 7 7 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBK22750.2 - 1.3e-06 27.9 0.0 6.1 6.2 0.0 5.8 5 0 0 5 5 5 0 AAA domain PduV-EutP PF10662.4 CBK22750.2 - 7.5e-06 25.4 6.9 0.89 9.0 0.0 5.8 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 CBK22750.2 - 1.7e-05 24.3 0.5 8.8 5.7 0.0 5.6 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CBK22750.2 - 2.6e-05 23.8 0.3 1.4 8.3 0.0 4.4 4 0 0 4 4 4 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 CBK22750.2 - 0.00024 20.8 4.2 5 6.7 0.0 5.0 6 0 0 6 6 4 0 NTPase MobB PF03205.9 CBK22750.2 - 0.00043 20.0 0.7 9.2 5.9 0.0 5.4 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 CBK22750.2 - 0.0005 19.6 0.0 2.5 7.5 0.0 4.1 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 CBK22750.2 - 0.0014 18.6 0.1 45 4.0 0.0 5.4 5 0 0 5 5 5 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CBK22750.2 - 1.2 9.4 0.0 0.42 10.9 0.0 10.5 10 2 0 10 10 6 0 AAA domain Filament PF00038.16 CBK22751.2 - 0.0012 18.3 6.8 0.0012 18.3 4.7 5.4 1 1 1 4 4 4 4 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBK22751.2 - 0.0043 16.7 7.3 0.0043 16.7 5.1 6.1 3 1 2 5 5 5 3 TPR/MLP1/MLP2-like protein DUF2353 PF09789.4 CBK22751.2 - 0.015 14.6 63.4 0.013 14.8 5.6 4.4 2 2 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) AAA_13 PF13166.1 CBK22751.2 - 0.018 13.5 65.5 0.0065 14.9 11.3 3.1 2 1 1 3 3 3 0 AAA domain Paralemmin PF03285.10 CBK22751.2 - 0.019 14.4 0.0 0.019 14.4 0.0 4.5 4 1 0 4 4 4 0 Paralemmin Matrilin_ccoil PF10393.4 CBK22751.2 - 0.63 9.4 11.9 16 4.9 0.0 4.8 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF869 PF05911.6 CBK22751.2 - 1.3 7.1 67.1 2.8 6.0 29.7 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF972 PF06156.8 CBK22751.2 - 2 8.7 63.0 0.76 10.1 3.2 7.8 1 1 5 7 7 7 0 Protein of unknown function (DUF972) IncA PF04156.9 CBK22751.2 - 3 7.3 88.7 0.23 11.0 4.9 5.6 1 1 3 6 6 6 0 IncA protein Pkinase PF00069.20 CBK22752.2 - 6.3e-38 130.4 0.1 1e-37 129.7 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22752.2 - 1.1e-20 73.7 0.0 7.7e-20 71.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBK22752.2 - 0.0001 21.2 0.3 0.00015 20.7 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CBK22752.2 - 0.025 13.9 0.0 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ank_4 PF13637.1 CBK22753.2 - 5.2e-11 42.7 0.0 5.1e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBK22753.2 - 1.3e-09 38.2 0.1 2e-07 31.2 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBK22753.2 - 5.6e-08 32.2 0.4 0.0044 16.7 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBK22753.2 - 2.9e-07 30.5 0.4 0.0006 19.9 0.1 3.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK22753.2 - 1e-05 25.2 0.0 0.03 14.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Nol1_Nop2_Fmu PF01189.12 CBK22754.2 - 1.5e-17 63.9 0.0 2.1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBK22754.2 - 7.6e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CBK22754.2 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBK22754.2 - 0.012 15.2 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HSP20 PF00011.16 CBK22755.2 - 3.1e-27 94.3 2.9 3.7e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3716 PF12511.3 CBK22755.2 - 0.063 12.9 1.0 0.47 10.1 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF104 PF01954.11 CBK22755.2 - 0.089 12.8 1.8 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK22755.2 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase HA2 PF04408.18 CBK22756.2 - 7.6e-22 77.2 0.0 1.7e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK22756.2 - 1.6e-18 66.5 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK22756.2 - 1.6e-12 47.0 0.0 1e-11 44.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK22756.2 - 4.8e-09 35.9 0.6 1.4e-07 31.1 0.2 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK22756.2 - 1.5e-06 28.3 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBK22756.2 - 0.00016 21.5 0.2 0.015 15.1 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CBK22756.2 - 0.0077 16.5 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBK22756.2 - 0.0082 15.6 0.1 0.66 9.3 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 CBK22756.2 - 0.015 15.0 0.1 0.042 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CBK22756.2 - 0.018 14.5 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CBK22756.2 - 0.027 13.4 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.5 CBK22756.2 - 0.048 12.8 0.1 6.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 CBK22756.2 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Flavi_DEAD PF07652.9 CBK22756.2 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 CBK22756.2 - 0.06 13.6 0.8 0.31 11.3 0.1 2.2 1 1 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 CBK22756.2 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ACR_tran PF00873.14 CBK22757.2 - 0.075 10.4 0.0 0.13 9.5 0.0 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMTV_SAg PF01054.12 CBK22758.2 - 0.11 11.4 0.0 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen TK PF00265.13 CBK22759.2 - 0.11 12.0 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase YbbR PF07949.7 CBK22759.2 - 0.14 12.3 0.4 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 YbbR-like protein zf-RING_2 PF13639.1 CBK22762.2 - 1.5e-10 40.6 4.2 2.4e-10 40.0 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK22762.2 - 2.2e-07 30.8 4.3 3.4e-07 30.2 3.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBK22762.2 - 1.1e-06 28.5 4.0 1.8e-06 27.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK22762.2 - 1.4e-06 27.8 1.7 2e-06 27.3 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK22762.2 - 5.3e-06 25.9 3.6 8.1e-06 25.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK22762.2 - 7.9e-06 25.5 2.6 1.2e-05 24.9 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBK22762.2 - 0.00054 19.7 1.1 0.00075 19.2 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 CBK22762.2 - 0.00084 18.6 0.1 0.00088 18.5 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBK22762.2 - 0.0058 16.3 2.3 0.012 15.3 1.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CBK22762.2 - 0.012 15.5 3.0 0.084 12.8 2.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 CBK22762.2 - 0.017 14.9 2.0 0.032 14.1 1.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CBK22762.2 - 0.025 14.5 2.8 0.043 13.8 1.9 1.3 1 0 0 1 1 1 0 RING-variant domain Fe-ADH PF00465.14 CBK22762.2 - 0.033 12.8 0.1 0.035 12.7 0.1 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase zf-RING_4 PF14570.1 CBK22762.2 - 0.13 11.8 1.4 0.24 11.0 1.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 CBK22762.2 - 0.16 11.6 3.0 9.8 5.9 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING-like PF08746.6 CBK22762.2 - 0.34 10.9 5.1 0.14 12.1 1.9 1.5 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 CBK22762.2 - 0.42 10.3 2.2 9.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 CBK22762.2 - 0.88 9.1 3.5 0.46 10.0 1.1 1.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Aminotran_1_2 PF00155.16 CBK22764.2 - 1.1e-37 129.8 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK22764.2 - 0.0025 17.0 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase DUF2478 PF10649.4 CBK22765.2 - 0.059 12.7 0.2 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) ATP_bind_3 PF01171.15 CBK22766.2 - 4e-10 39.4 0.0 9.3e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 CBK22766.2 - 0.022 13.3 0.2 0.035 12.6 0.1 1.3 1 1 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 CBK22766.2 - 0.053 13.0 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase AAA PF00004.24 CBK22768.2 - 4.3e-44 149.8 0.0 6.7e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBK22768.2 - 2.2e-06 26.8 0.0 5.7e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBK22768.2 - 9.4e-05 21.2 0.0 0.00015 20.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 CBK22768.2 - 0.00029 20.8 0.0 0.0078 16.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBK22768.2 - 0.00038 20.2 0.0 0.0066 16.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBK22768.2 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBK22768.2 - 0.011 15.8 0.0 0.21 11.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBK22768.2 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBK22768.2 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBK22768.2 - 0.018 15.8 0.0 0.045 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBK22768.2 - 0.041 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CBK22768.2 - 0.049 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 CBK22768.2 - 0.075 12.1 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBK22768.2 - 0.095 12.3 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Taxilin PF09728.4 CBK22770.2 - 0.046 12.8 2.6 0.046 12.7 1.8 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ELO PF01151.13 CBK22771.2 - 2.5e-60 203.8 22.5 2.5e-60 203.8 15.6 1.4 2 0 0 2 2 2 1 GNS1/SUR4 family Rho_Binding PF08912.6 CBK22772.2 - 0.045 14.0 2.3 0.045 14.0 1.6 2.4 2 0 0 2 2 2 0 Rho Binding HALZ PF02183.13 CBK22772.2 - 0.11 12.1 4.8 1.4 8.7 1.3 2.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3972 PF13118.1 CBK22772.2 - 0.46 10.5 5.7 2.4 8.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Sigma70_ner PF04546.8 CBK22772.2 - 1.5 8.3 9.6 0.22 11.0 1.9 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region DUF342 PF03961.8 CBK22772.2 - 1.6 7.0 4.3 2.1 6.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NYD-SP28_assoc PF14775.1 CBK22772.2 - 1.8 8.3 8.7 0.15 11.7 1.5 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain DivIC PF04977.10 CBK22772.2 - 2.6 7.5 9.8 1.2 8.6 1.4 2.6 1 1 1 2 2 2 0 Septum formation initiator Ndc1_Nup PF09531.5 CBK22772.2 - 2.9 6.2 7.6 3.7 5.8 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FlgN PF05130.7 CBK22772.2 - 3 8.0 8.4 7.7 6.7 5.8 1.7 1 1 0 1 1 1 0 FlgN protein TSC22 PF01166.13 CBK22772.2 - 3.3 7.7 10.7 0.21 11.5 3.1 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 CBK22772.2 - 6.1 7.2 8.6 1.4 9.3 1.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CBK22772.2 - 6.6 6.2 14.3 26 4.3 9.6 1.9 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBK22772.2 - 6.8 6.5 12.6 1.4e+02 2.3 6.3 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_C13 PF01650.13 CBK22774.2 - 2.7e-53 180.8 0.0 3.7e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.13 CBK22775.2 - 3.7e-53 180.4 0.0 5.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF563 PF04577.9 CBK22776.2 - 0.00024 21.0 0.1 0.00059 19.8 0.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF563) PfkB PF00294.19 CBK22776.2 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Connexin_CCC PF10582.4 CBK22776.2 - 0.77 9.6 4.8 34 4.3 0.1 3.4 3 0 0 3 3 3 0 Gap junction channel protein cysteine-rich domain DUF1394 PF07159.7 CBK22777.2 - 1.3e-07 31.0 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF1315 PF07023.7 CBK22778.2 - 0.0066 16.3 0.0 0.0087 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) Pkinase PF00069.20 CBK22779.2 - 3e-71 239.6 0.0 3.6e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22779.2 - 3.8e-42 144.1 0.0 4.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22779.2 - 0.00032 19.7 0.0 0.0018 17.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBK22779.2 - 0.0037 16.3 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK22779.2 - 0.0085 15.4 0.3 0.03 13.6 0.2 1.7 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 CBK22779.2 - 0.0091 14.8 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBK22779.2 - 0.019 14.7 0.1 0.045 13.4 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.4 CBK22779.2 - 0.027 13.0 0.2 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 CBK22779.2 - 0.033 13.7 2.1 0.091 12.3 1.5 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CBK22779.2 - 0.077 12.3 0.2 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PRMT5 PF05185.11 CBK22780.2 - 2.5e-107 359.6 0.0 3e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CBK22780.2 - 0.0038 17.2 0.0 0.0084 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK22780.2 - 0.013 16.0 0.0 0.029 14.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 CBK22780.2 - 0.017 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 CBK22780.2 - 0.023 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CBK22780.2 - 0.072 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.22 CBK22781.2 - 1.5e-41 141.8 0.4 1.8e-41 141.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK22781.2 - 4.5e-09 36.3 0.1 1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CBK22781.2 - 0.0018 18.1 0.0 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RNA_pol_Rpb4 PF03874.11 CBK22782.2 - 0.0011 18.9 1.2 0.0017 18.3 0.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 Acetyltransf_2 PF00797.12 CBK22782.2 - 0.073 12.6 0.5 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 N-acetyltransferase RST PF12174.3 CBK22782.2 - 0.084 12.6 1.1 0.22 11.3 0.0 2.2 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Cpn60_TCP1 PF00118.19 CBK22783.2 - 3e-81 273.5 0.2 3.6e-81 273.2 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IF4E PF01652.13 CBK22784.2 - 9.3e-15 54.5 1.0 7.1e-14 51.6 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CBK22785.2 - 7.5e-43 146.5 0.0 1.2e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22785.2 - 4.6e-17 61.9 0.0 6.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22785.2 - 2.1e-11 43.3 0.0 1.1e-09 37.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBK22785.2 - 5.6e-09 36.0 2.2 0.00047 19.9 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CBK22785.2 - 6.9e-07 28.5 0.1 1.9e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBK22785.2 - 0.00096 18.5 1.1 0.012 15.0 0.0 2.7 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBK22785.2 - 0.0089 15.3 0.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DHDPS PF00701.17 CBK22785.2 - 0.24 9.9 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family TPR_19 PF14559.1 CBK22786.2 - 0.071 13.4 0.2 0.26 11.6 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 CBK22787.2 - 6.8e-05 22.1 24.2 0.0014 17.8 2.1 3.8 1 1 3 4 4 4 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBK22787.2 - 0.00041 20.2 20.0 0.00041 20.2 13.9 4.9 1 1 4 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 CBK22787.2 - 0.0066 16.2 7.3 0.0066 16.2 5.1 7.3 3 2 3 7 7 7 3 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 CBK22787.2 - 0.069 12.5 71.3 0.1 12.0 13.1 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) IncA PF04156.9 CBK22787.2 - 0.58 9.7 96.2 0.28 10.7 10.6 4.4 1 1 3 4 4 4 0 IncA protein GAS PF13851.1 CBK22787.2 - 4.2 6.5 81.3 7.7 5.6 18.9 4.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 CBK22787.2 - 4.4 6.7 83.0 0.27 10.6 2.5 6.2 1 1 5 6 6 6 0 Phage minor structural protein GP20 AAA_13 PF13166.1 CBK22787.2 - 7.8 4.8 64.0 0.05 12.0 15.8 3.0 1 1 2 3 3 3 0 AAA domain dCMP_cyt_deam_1 PF00383.17 CBK22788.2 - 2.2e-26 91.4 0.2 3.6e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PWWP PF00855.12 CBK22788.2 - 1.4e-06 28.3 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PWWP domain zf-4CXXC_R1 PF10497.4 CBK22789.2 - 0.1 12.7 18.5 0.19 11.8 12.8 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ank PF00023.25 CBK22790.2 - 1.5e-09 37.2 0.2 1.3e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBK22790.2 - 2.5e-08 33.3 0.2 7.1e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBK22790.2 - 1.3e-07 31.8 0.0 0.00025 21.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBK22790.2 - 1.4e-07 31.4 0.0 2.2e-05 24.5 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBK22790.2 - 2.1e-06 28.0 0.0 0.017 15.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Hist_deacetyl PF00850.14 CBK22791.2 - 4.2e-46 157.6 0.0 1.1e-45 156.2 0.0 1.7 1 1 0 1 1 1 1 Histone deacetylase domain GPI PF06560.6 CBK22792.2 - 0.1 11.6 0.5 0.13 11.2 0.4 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MORN_2 PF07661.8 CBK22794.2 - 0.1 12.7 9.5 8.9 6.6 0.4 4.0 3 0 0 3 3 3 0 MORN repeat variant 6PF2K PF01591.13 CBK22795.2 - 5.8e-55 185.7 0.0 8.8e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase UpxZ PF06603.6 CBK22795.2 - 0.036 14.0 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists ABC_tran PF00005.22 CBK22796.2 - 6.1e-45 152.8 0.0 2.8e-21 76.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBK22796.2 - 1.8e-14 54.3 7.9 0.00011 22.2 0.2 4.4 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 CBK22796.2 - 1e-13 50.8 0.2 1e-13 50.8 0.1 2.9 4 0 0 4 4 3 1 ABC transporter SMC_N PF02463.14 CBK22796.2 - 3.4e-10 39.5 0.9 0.00019 20.7 0.2 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBK22796.2 - 4.3e-06 26.0 4.7 0.12 11.4 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CBK22796.2 - 4.4e-06 26.8 0.1 0.022 14.9 0.0 3.0 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CBK22796.2 - 6.2e-06 26.0 0.2 0.0072 16.2 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 CBK22796.2 - 1.7e-05 25.2 0.3 0.045 14.2 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CBK22796.2 - 2.1e-05 23.7 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBK22796.2 - 2.4e-05 25.1 1.9 0.31 11.8 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA_16 PF13191.1 CBK22796.2 - 2.4e-05 24.3 0.4 0.22 11.4 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CBK22796.2 - 7.1e-05 22.2 0.1 0.055 12.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CBK22796.2 - 7.7e-05 22.1 0.7 0.45 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBK22796.2 - 0.00013 22.0 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 CBK22796.2 - 0.00055 19.8 0.4 0.29 11.1 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBK22796.2 - 0.00065 19.6 0.5 2.6 7.9 0.1 3.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 CBK22796.2 - 0.00075 19.2 0.1 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 CBK22796.2 - 0.00089 19.0 0.2 2 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CBK22796.2 - 0.0011 19.1 0.0 0.84 9.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBK22796.2 - 0.0014 18.3 0.6 0.1 12.2 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 CBK22796.2 - 0.0016 18.2 1.0 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 CBK22796.2 - 0.0018 18.2 0.0 0.41 10.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 CBK22796.2 - 0.0035 16.2 0.0 0.24 10.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 CBK22796.2 - 0.0054 16.2 0.0 2.4 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 CBK22796.2 - 0.0089 15.7 0.1 3.4 7.3 0.0 2.7 2 0 0 2 2 2 1 NTPase MobB PF03205.9 CBK22796.2 - 0.014 15.0 0.1 4.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CBK22796.2 - 0.036 13.9 2.1 3.1 7.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CBK22796.2 - 0.036 13.6 0.1 5.1 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBK22796.2 - 0.039 12.7 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ATP-synt_ab PF00006.20 CBK22796.2 - 0.11 11.9 0.0 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 CBK22796.2 - 0.2 11.9 10.4 3.2 8.0 0.0 4.1 4 1 1 5 5 4 0 AAA domain Dynamin_N PF00350.18 CBK22796.2 - 0.25 11.1 2.3 13 5.5 0.3 2.9 2 1 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 CBK22796.2 - 0.43 10.8 12.8 0.91 9.8 0.2 3.7 3 1 0 4 4 4 0 AAA domain Vps16_N PF04841.8 CBK22797.2 - 2.1e-31 108.8 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 CBK22797.2 - 5.7e-08 32.0 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_C PF04840.7 CBK22798.2 - 9.6e-28 97.0 0.1 9.8e-28 97.0 0.1 1.0 1 0 0 1 1 1 1 Vps16, C-terminal region DAGK_acc PF00609.14 CBK22799.2 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBK22799.2 - 4.7e-23 81.0 0.0 7.9e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CBK22799.2 - 1.6e-09 37.3 5.4 3.1e-09 36.4 3.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 CBK22799.2 - 1.4 8.8 8.5 3.8 7.4 5.9 1.8 1 0 0 1 1 1 0 Ring finger domain Indigoidine_A PF04227.7 CBK22801.2 - 1.7e-10 40.6 0.0 2.1e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Succ_DH_flav_C PF02910.15 CBK22803.2 - 1.2e-30 105.9 0.3 1.3e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.19 CBK22804.2 - 2.1e-121 405.7 3.2 2.7e-121 405.3 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBK22804.2 - 7.9e-48 161.5 1.8 1.2e-47 161.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBK22804.2 - 1.2e-06 27.6 0.1 1e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBK22804.2 - 1.4e-06 27.5 0.2 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CBK22804.2 - 2.7e-05 24.1 1.4 0.00035 20.5 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBK22804.2 - 4.6e-05 22.4 0.9 0.0025 16.7 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CBK22804.2 - 0.00027 20.0 0.2 0.00046 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CBK22804.2 - 0.016 15.4 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 CBK22804.2 - 0.022 13.2 1.5 0.039 12.4 0.2 1.9 3 0 0 3 3 3 0 HI0933-like protein WD40 PF00400.27 CBK22806.2 - 1.5e-21 75.4 14.1 3.7e-09 36.1 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBK22806.2 - 6.2e-19 67.6 0.0 1.6e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex IKI3 PF04762.7 CBK22806.2 - 0.0031 15.3 0.9 0.7 7.6 0.0 2.3 1 1 1 2 2 2 2 IKI3 family RRM_1 PF00076.17 CBK22807.2 - 7.2e-14 51.1 0.0 1.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22807.2 - 2.3e-12 46.5 0.0 3.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK22807.2 - 2.5e-12 46.5 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK22807.2 - 0.0043 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CBK22807.2 - 0.0044 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 CBK22807.2 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain DUF1765 PF08578.5 CBK22808.2 - 2.3e-10 40.5 3.2 2.3e-10 40.5 2.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) AAA_5 PF07728.9 CBK22809.2 - 6.7e-56 187.8 0.0 8.1e-14 51.5 0.0 7.0 6 0 0 6 6 6 5 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK22809.2 - 1.1e-15 57.9 3.2 0.039 14.0 0.0 8.3 7 2 0 7 7 6 3 AAA domain AAA_14 PF13173.1 CBK22809.2 - 4.5e-13 49.2 2.1 0.0064 16.3 0.0 6.6 6 0 0 6 6 6 3 AAA domain AAA_3 PF07726.6 CBK22809.2 - 1.5e-11 43.9 0.0 2.7e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBK22809.2 - 3.5e-07 29.8 0.0 0.004 16.6 0.0 4.5 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA PF00004.24 CBK22809.2 - 4.4e-07 30.1 0.6 0.044 13.9 0.0 5.8 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK22809.2 - 3.4e-05 23.9 0.6 1.1 9.2 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain AAA_33 PF13671.1 CBK22809.2 - 8.4e-05 22.4 0.0 0.33 10.8 0.0 4.5 5 0 0 5 5 5 1 AAA domain AAA_10 PF12846.2 CBK22809.2 - 0.0011 18.5 0.0 0.027 13.9 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_17 PF13207.1 CBK22809.2 - 0.0014 19.4 0.7 3.2 8.6 0.0 5.9 6 0 0 6 6 5 1 AAA domain MobB PF03205.9 CBK22809.2 - 0.0017 18.0 1.7 0.028 14.1 0.0 3.6 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2930 PF11152.3 CBK22809.2 - 0.006 15.7 0.1 0.02 14.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2930) AAA_19 PF13245.1 CBK22809.2 - 0.021 14.5 0.0 6.3 6.6 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CBK22809.2 - 0.031 13.7 0.3 17 4.8 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family VWA_2 PF13519.1 CBK22809.2 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_29 PF13555.1 CBK22809.2 - 0.12 11.9 0.0 9.2 5.8 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CBK22809.2 - 0.22 11.0 0.0 36 3.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain HRM PF02793.17 CBK22810.2 - 2.8e-13 49.6 90.4 0.00072 19.5 0.5 13.3 7 3 4 11 11 11 8 Hormone receptor domain fn3 PF00041.16 CBK22810.2 - 3.8e-10 39.7 0.3 0.0013 18.8 0.0 5.1 5 0 0 5 5 5 4 Fibronectin type III domain Big_5 PF13205.1 CBK22810.2 - 5.4e-08 33.3 6.3 9.8e-06 26.1 0.0 4.9 3 1 1 4 4 4 2 Bacterial Ig-like domain Zn_ribbon_2 PF12674.2 CBK22811.2 - 0.029 14.7 11.7 0.41 11.0 6.2 3.5 3 1 0 3 3 3 0 Putative zinc ribbon domain UPF0728 PF15092.1 CBK22811.2 - 0.14 12.0 0.5 16 5.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 ABC_tran PF00005.22 CBK22812.2 - 7.1e-34 117.0 0.0 1.3e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBK22812.2 - 2.7e-14 53.8 7.0 0.0089 16.0 0.0 4.5 3 2 1 5 5 4 4 AAA domain SMC_N PF02463.14 CBK22812.2 - 1.5e-13 50.5 1.9 0.00032 19.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 CBK22812.2 - 7.2e-12 44.6 3.4 7.2e-12 44.6 2.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 CBK22812.2 - 3.3e-08 32.8 3.0 3.3e-08 32.8 2.1 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.1 CBK22812.2 - 9.4e-08 31.5 0.2 0.44 9.5 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain Fer4_6 PF12837.2 CBK22812.2 - 4.3e-06 26.3 10.0 6.4e-06 25.7 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 CBK22812.2 - 1.2e-05 25.4 0.3 0.029 14.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CBK22812.2 - 3.1e-05 23.6 0.4 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CBK22812.2 - 4.2e-05 23.7 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 CBK22812.2 - 5.3e-05 23.5 0.2 5.3e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain DUF258 PF03193.11 CBK22812.2 - 6.7e-05 22.1 0.0 0.36 10.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK22812.2 - 9.5e-05 21.8 0.1 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 CBK22812.2 - 0.00015 21.3 1.4 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.2 CBK22812.2 - 0.00019 21.1 1.9 0.00019 21.1 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain MobB PF03205.9 CBK22812.2 - 0.0002 21.1 0.7 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBK22812.2 - 0.00026 21.8 0.7 0.11 13.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK22812.2 - 0.00026 20.8 0.1 0.12 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK22812.2 - 0.00042 20.3 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.1 CBK22812.2 - 0.00053 20.2 2.3 0.00053 20.2 1.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_23 PF13476.1 CBK22812.2 - 0.0006 20.2 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBK22812.2 - 0.00063 20.2 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 CBK22812.2 - 0.00064 19.5 0.0 0.17 11.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 CBK22812.2 - 0.00075 19.0 0.0 0.79 9.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_10 PF13237.1 CBK22812.2 - 0.0012 18.5 1.7 0.0012 18.5 1.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 CBK22812.2 - 0.0015 18.6 0.0 2.7 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 CBK22812.2 - 0.0019 17.8 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_16 PF13484.1 CBK22812.2 - 0.002 18.8 0.2 0.002 18.8 0.1 2.2 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain AAA_18 PF13238.1 CBK22812.2 - 0.0034 17.6 0.0 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBK22812.2 - 0.0042 15.8 0.1 0.059 12.0 0.0 2.4 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 CBK22812.2 - 0.0058 16.4 11.4 0.019 14.8 8.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CBK22812.2 - 0.0091 15.4 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBK22812.2 - 0.012 15.3 0.6 1 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_3 PF12798.2 CBK22812.2 - 0.013 16.0 4.7 0.013 16.0 3.2 2.2 2 0 0 2 2 1 0 4Fe-4S binding domain DUF815 PF05673.8 CBK22812.2 - 0.017 14.0 0.1 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 CBK22812.2 - 0.018 14.3 0.1 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 CBK22812.2 - 0.022 14.7 1.7 1.9 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Fer4_15 PF13459.1 CBK22812.2 - 0.023 15.2 0.6 0.073 13.6 0.5 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain AAA_30 PF13604.1 CBK22812.2 - 0.024 14.1 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBK22812.2 - 0.036 13.9 0.1 5.6 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CBK22812.2 - 0.036 14.4 2.5 0.036 14.4 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain TrwB_AAD_bind PF10412.4 CBK22812.2 - 0.038 12.6 0.2 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 CBK22812.2 - 0.062 12.9 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CBK22812.2 - 0.076 12.7 1.2 10 5.8 0.0 3.1 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 CBK22812.2 - 0.092 11.7 0.0 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 CBK22812.2 - 0.11 11.3 0.1 5.9 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CBK22812.2 - 0.14 11.6 0.9 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF359 PF04019.7 CBK22812.2 - 0.14 11.5 0.2 0.39 10.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF359) AAA_24 PF13479.1 CBK22812.2 - 0.14 11.6 0.3 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK22812.2 - 0.24 10.2 0.9 0.84 8.4 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_13 PF13166.1 CBK22812.2 - 0.34 9.3 1.2 0.53 8.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.1 CBK22812.2 - 0.6 10.1 8.5 0.098 12.7 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK22812.2 - 3.3 8.1 8.8 0.49 10.8 2.9 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain tRNA-synt_1b PF00579.20 CBK22814.2 - 9.2e-73 244.8 0.0 1.2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) VBS PF08913.5 CBK22814.2 - 0.026 14.7 0.0 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 Vinculin Binding Site GATase_5 PF13507.1 CBK22815.2 - 9.6e-106 352.4 0.0 1.4e-105 351.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CBK22815.2 - 4.7e-38 130.5 2.3 1.1e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CBK22815.2 - 1.5e-16 60.4 0.9 2e-15 56.8 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Epimerase PF01370.16 CBK22816.2 - 1.9e-62 210.7 0.4 2.7e-62 210.2 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBK22816.2 - 4.6e-26 91.1 0.3 6.2e-26 90.7 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK22816.2 - 6.1e-23 81.1 0.1 6.1e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CBK22816.2 - 1.9e-22 79.4 0.0 3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Histone PF00125.19 CBK22816.2 - 3.6e-21 75.0 0.1 6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 NAD_binding_4 PF07993.7 CBK22816.2 - 1.6e-20 73.1 0.3 2e-17 62.9 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 CBK22816.2 - 1.1e-05 25.4 0.0 4.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding CBFD_NFYB_HMF PF00808.18 CBK22816.2 - 0.017 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4110 PF13422.1 CBK22817.2 - 0.017 14.9 2.6 0.022 14.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Tho2 PF11262.3 CBK22817.2 - 0.06 12.3 2.4 0.071 12.1 1.7 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PHD PF00628.24 CBK22818.2 - 5.9e-11 41.8 38.7 0.00014 21.4 6.2 3.3 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.1 CBK22818.2 - 0.0022 17.2 14.4 0.0067 15.7 3.6 4.6 5 1 1 6 6 6 2 PHD-finger He_PIG PF05345.7 CBK22819.2 - 2.5e-27 94.6 47.7 1e-06 28.6 0.8 7.6 8 0 0 8 8 8 6 Putative Ig domain F5_F8_type_C PF00754.20 CBK22819.2 - 2e-06 27.6 20.2 0.0014 18.4 2.1 4.0 3 0 0 3 3 3 2 F5/8 type C domain I-set PF07679.11 CBK22819.2 - 0.0027 17.5 5.4 6 6.8 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain Shisa PF13908.1 CBK22819.2 - 0.012 15.7 1.7 0.024 14.7 1.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 CBK22819.2 - 0.036 13.6 0.4 0.055 13.0 0.3 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK22819.2 - 0.3 11.1 13.1 4.2 7.4 0.1 5.1 5 0 0 5 5 5 0 Hormone receptor domain Colicin_D PF11429.3 CBK22819.2 - 1.2 9.3 7.1 0.12 12.5 0.8 2.5 3 0 0 3 3 3 0 Colicin D hEGF PF12661.2 CBK22819.2 - 2.6 8.3 5.4 36 4.7 0.1 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF MatE PF01554.13 CBK22820.2 - 1.1e-32 112.8 22.6 1.4e-19 70.3 2.2 2.7 2 1 0 2 2 2 2 MatE IF4E PF01652.13 CBK22821.2 - 3.4e-30 104.7 1.1 6.6e-30 103.8 0.7 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E PCNA_N PF00705.13 CBK22822.2 - 2.8e-48 162.6 3.4 4.6e-48 161.9 2.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CBK22822.2 - 7.1e-44 148.8 0.0 1.3e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CBK22822.2 - 4.1e-07 29.0 0.7 5.5e-06 25.3 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBK22822.2 - 2e-05 23.8 0.1 2.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBK22822.2 - 0.024 13.5 0.0 2.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein Collagen PF01391.13 CBK22823.2 - 3.3e-60 199.4 236.8 4.7e-09 35.6 23.7 8.1 2 2 7 9 9 9 9 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.21 CBK22824.2 - 1.4e-18 65.9 29.2 2.4e-05 24.3 0.2 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBK22824.2 - 2.4e-18 65.4 31.5 9.6e-09 35.1 1.0 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBK22824.2 - 2.7e-16 58.6 24.5 5.8e-05 23.1 0.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 CBK22824.2 - 0.087 13.0 11.2 0.57 10.4 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBK22824.2 - 0.53 10.5 0.0 0.53 10.5 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBK22824.2 - 0.9 9.5 13.9 13 5.8 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger OAF PF14941.1 CBK22824.2 - 3.4 6.7 12.5 1.9 7.5 2.3 2.4 1 1 1 2 2 2 0 Transcriptional regulator, Out at first Isy1 PF06246.7 CBK22826.2 - 1e-59 202.0 2.7 1.2e-59 201.8 1.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF4559 PF15112.1 CBK22826.2 - 0.07 12.2 0.4 0.099 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) PCNA_N PF00705.13 CBK22827.2 - 2.8e-48 162.6 3.4 4.6e-48 161.9 2.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CBK22827.2 - 7.1e-44 148.8 0.0 1.3e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CBK22827.2 - 4.1e-07 29.0 0.7 5.5e-06 25.3 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBK22827.2 - 2e-05 23.8 0.1 2.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBK22827.2 - 0.024 13.5 0.0 2.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein IF4E PF01652.13 CBK22828.2 - 3.4e-30 104.7 1.1 6.6e-30 103.8 0.7 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E PCNA_N PF00705.13 CBK22829.2 - 2.8e-48 162.6 3.4 4.6e-48 161.9 2.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CBK22829.2 - 7.1e-44 148.8 0.0 1.3e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CBK22829.2 - 4.1e-07 29.0 0.7 5.5e-06 25.3 0.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CBK22829.2 - 2e-05 23.8 0.1 2.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 CBK22829.2 - 0.024 13.5 0.0 2.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein ESSS PF10183.4 CBK22831.2 - 1.4e-09 38.2 0.1 1.7e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Histone PF00125.19 CBK22831.2 - 0.078 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Cyclin PF08613.6 CBK22832.2 - 1.9e-10 41.3 0.8 2.6e-10 40.8 0.6 1.2 1 0 0 1 1 1 1 Cyclin RNA_pol_Rpc82 PF05645.8 CBK22834.2 - 0.00016 21.2 0.4 0.00065 19.3 0.1 2.0 2 1 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 CBK22834.2 - 0.0018 17.7 1.1 0.0088 15.5 0.0 2.5 3 0 0 3 3 3 1 TFIIE alpha subunit BLOC1_2 PF10046.4 CBK22835.2 - 5e-06 26.5 0.3 6.4e-06 26.2 0.2 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 CBK22835.2 - 0.0025 16.5 0.2 0.0029 16.3 0.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein iPGM_N PF06415.8 CBK22836.2 - 1.3e-08 34.4 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 CBK22836.2 - 0.00023 20.6 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CBK22837.2 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 CBK22837.2 - 0.007 15.7 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Macro PF01661.16 CBK22838.2 - 8.2e-07 28.9 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain Utp13 PF08625.6 CBK22838.2 - 0.092 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain RRM_6 PF14259.1 CBK22839.2 - 2.2e-15 56.3 0.1 6.8e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK22839.2 - 5.1e-15 54.8 0.0 9.5e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK22839.2 - 2.2e-10 40.2 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 CBK22840.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK22840.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain OmpH PF03938.9 CBK22841.2 - 0.0023 17.9 11.3 0.003 17.5 7.8 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) APG6 PF04111.7 CBK22841.2 - 0.015 14.4 13.7 0.019 14.0 9.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBK22841.2 - 0.015 14.9 18.1 0.019 14.5 12.5 1.2 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 CBK22841.2 - 0.02 13.4 12.3 0.027 12.9 8.5 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.1 CBK22841.2 - 0.034 11.8 12.4 0.038 11.6 8.6 1.0 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.1 CBK22841.2 - 0.035 14.1 10.2 0.12 12.3 7.0 1.8 1 1 0 1 1 1 0 Syntaxin-like protein DUF3037 PF11236.3 CBK22841.2 - 0.052 13.5 1.6 0.4 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Ly49 PF08391.5 CBK22841.2 - 0.34 11.0 16.2 0.67 10.0 3.1 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Hemerythrin PF01814.18 CBK22841.2 - 0.47 10.6 6.7 5 7.2 4.6 2.2 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF607 PF04678.8 CBK22841.2 - 1.4 8.7 9.1 3.3 7.5 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF607 ADIP PF11559.3 CBK22841.2 - 1.5 8.6 19.8 0.86 9.5 9.7 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 CBK22841.2 - 1.6 8.7 22.7 0.16 12.0 8.3 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Spc7 PF08317.6 CBK22841.2 - 1.9 7.0 20.6 2.3 6.7 14.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.9 CBK22841.2 - 6.3 6.3 20.2 1.3 8.5 11.9 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4200 PF13863.1 CBK22841.2 - 6.5 6.7 28.4 46 3.9 18.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 CBK22841.2 - 7.5 6.1 23.6 2 8.0 7.7 2.0 1 1 1 2 2 2 0 Mnd1 family AAA_12 PF13087.1 CBK22842.2 - 9.8e-52 175.2 0.1 2.4e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBK22842.2 - 4.7e-41 140.8 0.3 1.5e-40 139.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK22842.2 - 3.6e-14 52.2 0.6 2.5e-12 46.3 0.5 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBK22842.2 - 1.4e-10 41.0 0.0 1e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CBK22842.2 - 1e-09 38.3 0.0 0.028 13.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CBK22842.2 - 2.6e-06 27.4 0.0 0.0013 18.8 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 CBK22842.2 - 3.1e-05 23.6 0.0 0.00045 19.9 0.0 2.5 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.1 CBK22842.2 - 0.00018 21.6 1.0 0.037 14.1 0.1 4.1 4 2 0 4 4 4 1 AAA domain AAA PF00004.24 CBK22842.2 - 0.00034 20.8 0.0 0.0083 16.3 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CBK22842.2 - 0.00086 18.3 0.1 0.02 13.8 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 CBK22842.2 - 0.00098 18.6 0.9 0.14 11.6 0.4 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 CBK22842.2 - 0.0017 17.7 0.0 0.042 13.1 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain T2SE PF00437.15 CBK22842.2 - 0.002 17.1 0.2 0.0046 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 CBK22842.2 - 0.0027 17.5 0.0 0.0092 15.8 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CBK22842.2 - 0.0033 17.4 2.5 0.041 13.8 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CBK22842.2 - 0.046 13.3 0.0 0.79 9.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 CBK22842.2 - 0.051 13.2 0.0 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 CBK22842.2 - 0.07 13.9 0.3 0.21 12.3 0.2 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK22842.2 - 0.12 11.8 0.8 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 CBK22842.2 - 0.23 10.2 1.1 1.5 7.5 0.1 2.6 2 1 1 3 3 3 0 SNF2 family N-terminal domain DUF4147 PF13660.1 CBK22843.2 - 1.4e-80 269.8 0.0 2e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.8 CBK22843.2 - 8.8e-37 125.5 2.0 2.3e-36 124.1 1.4 1.8 1 0 0 1 1 1 1 MOFRL family FLgD_tudor PF13861.1 CBK22843.2 - 0.97 9.4 4.9 2.3 8.2 0.5 2.9 3 0 0 3 3 3 0 FlgD Tudor-like domain DUF4490 PF14892.1 CBK22844.2 - 0.13 11.9 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) AIRS_C PF02769.17 CBK22846.2 - 1.7e-22 80.1 0.1 2.4e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PsaA_PsaB PF00223.14 CBK22846.2 - 0.055 11.5 0.1 0.066 11.2 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein CAF1C_H4-bd PF12265.3 CBK22847.2 - 1.9e-07 30.9 0.4 4.6e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CBK22848.2 - 0.025 14.4 0.0 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat MIF4G PF02854.14 CBK22849.2 - 1.9e-06 27.4 4.1 4.2e-06 26.3 2.9 1.6 1 0 0 1 1 1 1 MIF4G domain Rep_fac_C PF08542.6 CBK22849.2 - 0.036 14.0 2.2 1.2 9.1 0.1 3.2 3 1 0 3 3 3 0 Replication factor C C-terminal domain MA3 PF02847.12 CBK22849.2 - 0.065 12.9 0.6 0.53 10.0 0.0 2.8 2 0 0 2 2 2 0 MA3 domain XPG_I_2 PF12813.2 CBK22850.2 - 3.3e-09 36.6 0.1 6.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Spore_coat_CotO PF14153.1 CBK22850.2 - 0.038 13.4 1.7 0.064 12.6 1.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO XPG_I PF00867.13 CBK22850.2 - 0.051 13.6 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 XPG I-region Tau95 PF09734.4 CBK22851.2 - 1.5e-26 93.5 1.7 7.5e-26 91.1 1.2 1.9 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Cas_Csa5 PF09702.5 CBK22851.2 - 0.067 13.2 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Adap_comp_sub PF00928.16 CBK22852.2 - 4.1e-57 193.2 0.1 5.7e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK22852.2 - 4.2e-06 26.5 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NAD_Gly3P_dh_C PF07479.9 CBK22853.2 - 8.3e-50 168.3 0.1 1.2e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CBK22853.2 - 1.4e-36 125.6 0.0 2.5e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CBK22853.2 - 0.003 17.9 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 CBK22854.2 - 6.8e-74 248.2 0.0 1e-73 247.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22854.2 - 3.1e-55 187.0 0.0 5.5e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22854.2 - 0.00061 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF148 PF02520.12 CBK22854.2 - 0.057 13.2 1.3 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 WHEP-TRS PF00458.15 CBK22854.2 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 WHEP-TRS domain Lactamase_B_3 PF13483.1 CBK22855.2 - 2.3e-25 89.1 0.3 2.8e-25 88.9 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 CBK22855.2 - 2.4e-16 59.8 2.4 2.9e-16 59.5 1.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK22855.2 - 1e-11 44.8 5.6 6.2e-11 42.3 3.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alpha-amylase_C PF02806.13 CBK22856.2 - 0.0012 18.8 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain LRR_8 PF13855.1 CBK22858.2 - 0.03 14.0 0.9 8.6 6.2 0.1 2.7 1 1 1 2 2 2 0 Leucine rich repeat MORN_2 PF07661.8 CBK22858.2 - 0.61 10.2 9.9 8.2 6.8 0.5 3.9 3 0 0 3 3 3 0 MORN repeat variant Ins_P5_2-kin PF06090.7 CBK22859.2 - 6.5e-17 61.5 0.0 8e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4379 PF14311.1 CBK22860.2 - 1.5e-28 98.3 17.9 3.1e-16 58.8 1.4 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4379) zf-Di19 PF05605.7 CBK22860.2 - 0.028 14.5 6.8 0.26 11.4 0.5 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.1 CBK22860.2 - 0.054 13.1 8.0 8.2 6.1 0.1 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.4 CBK22860.2 - 0.19 11.6 2.9 14 5.6 0.0 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-C2HC5 PF06221.8 CBK22860.2 - 0.35 10.6 5.0 7.1 6.4 0.2 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type FANCL_C PF11793.3 CBK22860.2 - 0.39 10.7 4.6 3.8 7.5 0.1 3.1 3 0 0 3 3 3 0 FANCL C-terminal domain zf-H2C2_2 PF13465.1 CBK22860.2 - 2.1 8.7 5.6 62 4.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_4 PF14570.1 CBK22860.2 - 2.6 7.6 7.5 11 5.7 0.2 3.4 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain zf-Sec23_Sec24 PF04810.10 CBK22860.2 - 5.2 6.7 10.0 4.1 7.0 0.1 3.6 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Zn_Tnp_IS1 PF03811.8 CBK22860.2 - 6.6 6.3 10.6 17 5.0 0.2 3.7 3 0 0 3 3 3 0 InsA N-terminal domain Cyclin_N PF00134.18 CBK22861.2 - 1.2e-15 57.1 1.9 1.3e-15 57.0 1.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyt_c_ox_IV PF12270.3 CBK22861.2 - 0.025 14.3 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV SK_channel PF03530.9 CBK22861.2 - 0.15 11.8 1.7 0.16 11.7 1.2 1.0 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Pkinase PF00069.20 CBK22862.2 - 1.1e-09 37.7 0.0 1.4e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Dus PF01207.12 CBK22863.2 - 9.1e-43 146.2 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CBK22863.2 - 0.032 13.8 8.4 0.038 13.6 0.5 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LamB PF02264.10 CBK22864.2 - 0.091 11.8 0.1 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 LamB porin hSac2 PF12456.3 CBK22865.2 - 0.064 12.6 0.7 8.1 5.8 0.0 3.3 1 1 2 3 3 3 0 Inositol phosphatase MORN_2 PF07661.8 CBK22865.2 - 0.25 11.4 11.0 8.5 6.7 0.5 4.4 4 0 0 4 4 4 0 MORN repeat variant AAA PF00004.24 CBK22866.2 - 5.1e-38 130.2 0.0 2e-37 128.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBK22866.2 - 8.3e-07 28.8 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CBK22866.2 - 1.9e-05 23.8 0.0 2.9e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK22866.2 - 2.3e-05 24.5 0.1 0.00013 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK22866.2 - 0.00014 21.5 0.1 0.0015 18.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBK22866.2 - 0.00017 21.0 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBK22866.2 - 0.0002 21.0 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 CBK22866.2 - 0.00028 20.0 0.1 0.43 9.6 0.0 3.0 2 1 1 3 3 3 1 KaiC AAA_33 PF13671.1 CBK22866.2 - 0.00043 20.1 0.4 0.0015 18.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK22866.2 - 0.00049 20.1 0.2 0.0047 16.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 CBK22866.2 - 0.00065 18.5 0.0 0.00097 17.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 CBK22866.2 - 0.00098 19.4 0.2 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBK22866.2 - 0.0012 19.6 0.1 0.0024 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK22866.2 - 0.0033 17.3 0.0 0.0073 16.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CBK22866.2 - 0.0044 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MHCassoc_trimer PF08831.5 CBK22866.2 - 0.0051 16.6 0.1 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Class II MHC-associated invariant chain trimerisation domain AAA_24 PF13479.1 CBK22866.2 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 CBK22866.2 - 0.0079 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 CBK22866.2 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CBK22866.2 - 0.012 15.0 0.8 0.051 12.9 0.2 2.3 1 1 2 3 3 3 0 AAA domain RNA_helicase PF00910.17 CBK22866.2 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CBK22866.2 - 0.015 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CBK22866.2 - 0.032 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 CBK22866.2 - 0.065 13.5 0.0 0.1 12.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CBK22866.2 - 0.069 12.6 0.0 0.25 10.7 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CBK22866.2 - 0.085 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CBK22866.2 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 CBK22866.2 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CBK22866.2 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 CBK22866.2 - 0.13 11.1 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PHO4 PF01384.15 CBK22867.2 - 3e-115 384.3 11.3 7.7e-114 379.7 7.8 2.0 1 1 0 1 1 1 1 Phosphate transporter family YajC PF02699.10 CBK22867.2 - 0.098 12.3 0.0 0.46 10.1 0.0 2.2 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4381 PF14316.1 CBK22867.2 - 0.28 11.2 0.0 0.28 11.2 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Na_H_antiporter PF03553.9 CBK22868.2 - 1.2e-48 165.7 15.5 1.2e-48 165.7 10.7 2.7 1 1 1 2 2 2 1 Na+/H+ antiporter family DUF4491 PF14898.1 CBK22868.2 - 0.0045 17.1 0.6 0.038 14.1 0.4 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4491) IncA PF04156.9 CBK22868.2 - 0.017 14.6 0.0 0.017 14.6 0.0 2.7 3 0 0 3 3 3 0 IncA protein DUF3278 PF11683.3 CBK22868.2 - 5.1 7.1 0.0 5.1 7.1 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3278) WD40 PF00400.27 CBK22869.2 - 4e-34 115.2 12.9 1.9e-10 40.2 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CBK22869.2 - 0.0048 16.6 0.1 4.7 6.8 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Collagen PF01391.13 CBK22869.2 - 1 8.9 24.8 36 3.9 17.2 2.3 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) HLH PF00010.21 CBK22870.2 - 9.6e-09 34.8 4.1 2.2e-08 33.6 2.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.1 CBK22870.2 - 0.0074 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain DUF2423 PF10338.4 CBK22870.2 - 0.047 13.6 1.6 0.059 13.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Laminin_I PF06008.9 CBK22870.2 - 0.058 12.7 3.5 0.077 12.3 2.5 1.1 1 0 0 1 1 1 0 Laminin Domain I PAS_4 PF08448.5 CBK22870.2 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 PAS fold IFP_35_N PF07334.8 CBK22870.2 - 0.086 12.8 0.4 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FliJ PF02050.11 CBK22870.2 - 0.13 12.3 4.3 0.19 11.7 3.0 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein bZIP_2 PF07716.10 CBK22870.2 - 0.33 10.7 3.0 5 7.0 0.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Filament PF00038.16 CBK22871.2 - 0.0081 15.6 44.7 0.14 11.6 10.5 3.4 1 1 3 4 4 4 3 Intermediate filament protein CCDC144C PF14915.1 CBK22871.2 - 0.061 12.2 46.1 0.23 10.3 20.8 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region PCP_red PF08369.5 CBK22871.2 - 0.097 12.5 0.4 0.097 12.5 0.2 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit GAS PF13851.1 CBK22871.2 - 0.11 11.6 38.9 0.79 8.8 13.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AP_endonuc_2 PF01261.19 CBK22871.2 - 0.55 9.4 4.9 16 4.7 3.2 2.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Tup_N PF08581.5 CBK22871.2 - 8.6 6.6 30.3 0.62 10.2 0.3 5.0 4 1 1 5 5 5 0 Tup N-terminal Histone PF00125.19 CBK22873.2 - 7.6e-33 112.4 0.5 1.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK22873.2 - 5.8e-05 23.1 0.1 8.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK22873.2 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK22874.2 - 9.7e-15 54.4 0.1 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBK22874.2 - 6e-05 22.9 0.1 8.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CBK22874.2 - 8.1e-05 22.7 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK22874.2 - 0.00075 19.5 0.1 0.0012 18.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBK22874.2 - 0.016 14.9 0.1 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HTH_17 PF12728.2 CBK22874.2 - 0.048 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-31kDa PF02291.10 CBK22874.2 - 0.07 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 CBK22874.2 - 0.15 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Fer2 PF00111.22 CBK22875.2 - 2.9e-12 46.1 0.8 4.4e-12 45.5 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4457 PF14652.1 CBK22876.2 - 1.3e-13 50.6 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) PBP1_TM PF14812.1 CBK22877.2 - 3.2 8.1 7.8 1.1 9.6 3.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_tran PF00005.22 CBK22878.2 - 2.1e-47 160.8 0.1 9.1e-29 100.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK22878.2 - 5.3e-43 147.3 29.5 7.5e-26 91.1 7.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBK22878.2 - 1.3e-07 31.0 8.3 8.2e-05 21.9 0.3 4.1 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 CBK22878.2 - 4e-05 23.1 0.2 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBK22878.2 - 8.8e-05 22.4 0.2 0.37 10.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CBK22878.2 - 0.00011 22.6 1.9 0.099 13.1 0.1 3.3 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 CBK22878.2 - 0.00012 21.5 0.6 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 CBK22878.2 - 0.00021 20.2 0.1 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 CBK22878.2 - 0.00024 21.9 0.0 1.4 9.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK22878.2 - 0.00048 19.3 0.6 0.18 10.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBK22878.2 - 0.00051 20.0 0.0 0.18 11.7 0.0 3.8 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 CBK22878.2 - 0.00074 19.3 4.2 0.075 12.8 0.2 3.8 3 1 0 3 3 3 1 Dynamin family AAA_25 PF13481.1 CBK22878.2 - 0.00089 18.7 0.9 0.26 10.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CBK22878.2 - 0.00099 18.9 5.6 0.26 11.0 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_16 PF13191.1 CBK22878.2 - 0.0023 17.9 0.7 0.1 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CBK22878.2 - 0.0033 16.5 3.1 0.4 9.7 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 CBK22878.2 - 0.004 17.3 3.4 2.2 8.4 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK22878.2 - 0.0065 16.6 4.6 3.2 7.9 0.0 4.5 4 1 0 4 4 3 1 AAA domain UPF0079 PF02367.12 CBK22878.2 - 0.0083 15.7 0.7 0.028 14.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CBK22878.2 - 0.0091 15.7 3.2 0.37 10.5 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2207 PF09972.4 CBK22878.2 - 0.0092 14.6 10.8 0.048 12.2 0.0 2.8 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) AAA_30 PF13604.1 CBK22878.2 - 0.01 15.4 2.9 2.9 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 CBK22878.2 - 0.018 14.5 0.8 0.4 10.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1505 PF07403.6 CBK22878.2 - 0.057 13.3 0.1 0.28 11.1 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) AAA_10 PF12846.2 CBK22878.2 - 0.069 12.5 8.7 9.4 5.5 0.2 3.4 2 1 0 3 3 3 0 AAA-like domain ATP_bind_1 PF03029.12 CBK22878.2 - 0.088 12.3 8.1 1.3 8.4 1.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 CBK22878.2 - 0.11 12.7 3.4 24 5.1 0.0 4.1 4 0 0 4 4 4 0 RNA helicase RseC_MucC PF04246.7 CBK22878.2 - 0.21 11.1 10.6 0.048 13.2 1.4 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC AAA_33 PF13671.1 CBK22878.2 - 0.22 11.4 1.0 4.9 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBK22878.2 - 0.3 10.7 2.8 1.3 8.6 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.1 CBK22878.2 - 8.9 6.5 10.1 14 5.9 0.0 3.8 3 1 0 3 3 3 0 AAA domain DUF1860 PF08949.5 CBK22881.2 - 0.049 13.2 1.0 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) KH_1 PF00013.24 CBK22882.2 - 1.1e-14 53.7 0.7 3.3e-11 42.6 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBK22882.2 - 2.3e-05 23.9 3.0 6.5e-05 22.4 0.1 3.2 3 2 1 4 4 4 1 KH domain KH_2 PF07650.12 CBK22882.2 - 0.00065 19.2 2.7 0.0024 17.3 1.2 2.6 1 1 1 2 2 2 1 KH domain KH_5 PF13184.1 CBK22882.2 - 0.0012 18.5 4.7 0.066 13.0 0.1 3.1 3 0 0 3 3 3 2 NusA-like KH domain Phage_HK97_TLTM PF06120.6 CBK22882.2 - 0.0034 16.7 2.7 0.004 16.5 1.6 1.4 1 1 0 1 1 1 1 Tail length tape measure protein MIS13 PF08202.6 CBK22882.2 - 0.006 15.6 6.6 0.01 14.9 4.5 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family NPV_P10 PF05531.7 CBK22882.2 - 0.19 11.9 1.0 0.98 9.7 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 CBK22882.2 - 0.5 9.9 6.7 1.4 8.5 0.1 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.6 CBK22882.2 - 1.3 9.5 13.1 4.2 7.8 3.0 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.13 CBK22882.2 - 7.3 5.5 12.4 4.5 6.2 5.4 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein KH_1 PF00013.24 CBK22883.2 - 2.7e-29 100.5 0.1 6.7e-08 32.0 0.0 6.2 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 CBK22883.2 - 9.6e-18 63.4 0.1 8.9e-05 22.0 0.0 5.1 5 0 0 5 5 5 4 KH domain SLS PF14611.1 CBK22883.2 - 4.6e-09 36.0 0.0 0.0062 15.9 0.0 4.1 2 2 2 4 4 4 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CBK22883.2 - 6.5e-09 35.2 1.5 0.011 15.2 0.0 3.6 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 CBK22883.2 - 0.0014 18.2 0.4 0.05 13.2 0.0 2.8 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 CBK22883.2 - 0.07 12.9 1.0 13 5.6 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain TolA PF06519.6 CBK22883.2 - 0.11 12.4 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 TolA C-terminal BRF1 PF07741.8 CBK22883.2 - 0.85 9.8 6.7 2 8.7 4.6 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Prefoldin_2 PF01920.15 CBK22885.2 - 3.1e-13 49.3 7.6 3.1e-13 49.3 5.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit zf-MYND PF01753.13 CBK22885.2 - 3.2e-09 36.5 16.8 3.2e-09 36.5 11.6 1.9 2 0 0 2 2 2 1 MYND finger Osmo_CC PF08946.5 CBK22885.2 - 0.0082 16.1 1.3 0.017 15.1 0.9 1.5 1 0 0 1 1 1 1 Osmosensory transporter coiled coil LRS4 PF10422.4 CBK22885.2 - 0.0089 15.4 7.9 0.01 15.2 5.5 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Matrilin_ccoil PF10393.4 CBK22885.2 - 0.053 12.8 3.6 0.055 12.8 0.4 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin BLOC1_2 PF10046.4 CBK22885.2 - 0.072 13.2 0.6 0.072 13.2 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.5 CBK22885.2 - 0.15 12.1 0.4 0.15 12.1 0.3 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil GAS PF13851.1 CBK22885.2 - 0.15 11.2 14.1 0.24 10.5 2.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.12 CBK22885.2 - 0.16 11.6 11.9 0.1 12.2 1.5 2.4 1 1 0 2 2 2 0 Prefoldin subunit Transposase_22 PF02994.9 CBK22885.2 - 0.19 10.1 8.6 0.23 9.9 6.0 1.0 1 0 0 1 1 1 0 L1 transposable element DUF2681 PF10883.3 CBK22885.2 - 0.21 11.7 0.3 0.21 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Cep57_CLD PF14073.1 CBK22885.2 - 0.23 11.2 11.7 0.29 10.9 8.1 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 NPV_P10 PF05531.7 CBK22885.2 - 0.41 10.9 2.5 2.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CBK22885.2 - 0.43 10.4 13.7 8.4 6.2 9.5 2.2 1 1 0 1 1 1 0 Tropomyosin like Uds1 PF15456.1 CBK22885.2 - 0.52 10.3 7.5 0.091 12.7 1.8 1.9 1 1 1 2 2 2 0 Up-regulated During Septation Syntaxin-6_N PF09177.6 CBK22885.2 - 0.53 10.7 5.7 2.1 8.7 0.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF489 PF04356.7 CBK22885.2 - 0.6 9.6 3.9 0.76 9.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Laminin_II PF06009.7 CBK22885.2 - 0.65 9.7 8.0 1.8 8.3 0.5 2.1 1 1 0 2 2 2 0 Laminin Domain II ADIP PF11559.3 CBK22885.2 - 0.69 9.8 10.3 0.28 11.0 0.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DMPK_coil PF08826.5 CBK22885.2 - 0.97 9.3 9.1 0.16 11.8 1.0 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF3450 PF11932.3 CBK22885.2 - 1.4 8.1 8.0 1.1 8.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.6 CBK22885.2 - 1.5 8.8 13.9 0.5 10.3 2.4 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.6 CBK22885.2 - 1.5 8.7 3.6 1.4 8.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC155 PF14662.1 CBK22885.2 - 1.6 8.2 12.2 7.1 6.1 8.5 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 FliJ PF02050.11 CBK22885.2 - 2.8 7.9 10.8 1.9 8.5 3.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.6 CBK22885.2 - 3.1 7.7 5.6 4.6 7.2 1.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AKNA PF12443.3 CBK22885.2 - 3.9 7.5 10.5 11 6.0 0.8 2.8 1 1 0 2 2 2 0 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.17 CBK22885.2 - 5.5 7.0 9.8 0.58 10.1 1.0 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-Q PF13094.1 CBK22885.2 - 6.5 6.7 10.5 3 7.8 1.0 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med4 PF10018.4 CBK22885.2 - 9.2 5.6 9.6 0.16 11.3 1.2 2.0 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Helicase_C PF00271.26 CBK22886.2 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBK22886.2 - 6.4e-05 23.1 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CBK22886.2 - 0.00014 21.4 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 CBK22886.2 - 0.00074 19.4 0.9 0.048 13.5 0.6 2.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBK22886.2 - 0.0068 16.1 0.1 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Viral_helicase1 PF01443.13 CBK22886.2 - 0.02 14.4 0.1 0.43 10.0 0.0 2.4 1 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CBK22886.2 - 0.039 13.5 0.1 0.094 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CBK22886.2 - 0.04 12.7 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CBK22886.2 - 0.043 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Helicase_RecD PF05127.9 CBK22886.2 - 0.045 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Helicase Sigma54_activat PF00158.21 CBK22886.2 - 0.082 12.3 0.2 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CBK22886.2 - 0.085 11.9 0.2 0.28 10.2 0.1 1.9 1 1 0 1 1 1 0 KaiC AAA_19 PF13245.1 CBK22886.2 - 0.15 11.8 0.1 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CBK22886.2 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Stc1 PF12898.2 CBK22887.2 - 0.0026 17.7 4.3 0.0032 17.4 3.0 1.2 1 0 0 1 1 1 1 Stc1 domain zf-C3HC4_3 PF13920.1 CBK22887.2 - 0.034 13.8 5.0 0.049 13.3 3.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 CBK22887.2 - 0.1 12.2 1.2 0.11 12.1 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C6_DPF PF10170.4 CBK22887.2 - 0.11 12.5 2.3 0.12 12.4 1.6 1.1 1 0 0 1 1 1 0 Cysteine-rich domain Endonuclease_7 PF02945.10 CBK22887.2 - 0.16 11.7 1.8 0.19 11.4 1.2 1.4 1 1 0 1 1 1 0 Recombination endonuclease VII DUF1272 PF06906.6 CBK22887.2 - 0.42 10.5 2.9 0.56 10.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.1 CBK22887.2 - 0.54 10.3 6.0 2 8.5 4.2 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK22887.2 - 0.85 9.4 7.7 1.7 8.3 5.3 1.5 1 1 0 1 1 1 0 zinc-RING finger domain TNFR_c6 PF00020.13 CBK22887.2 - 5.4 7.1 7.7 3.8 7.6 0.2 2.1 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region He_PIG PF05345.7 CBK22888.2 - 3.8e-11 42.8 0.0 2.3e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Putative Ig domain Phospholamban PF04272.9 CBK22888.2 - 0.04 13.3 0.1 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Phospholamban DUF1129 PF06570.6 CBK22888.2 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Hum_adeno_E3A PF05393.6 CBK22888.2 - 0.12 12.0 0.6 0.28 10.8 0.4 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein ODV-E18 PF10717.4 CBK22888.2 - 0.14 11.5 0.6 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SNF2_N PF00176.18 CBK22889.2 - 9.2e-79 264.3 1.4 1.4e-78 263.7 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK22889.2 - 8.6e-17 60.7 0.0 3.7e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBK22889.2 - 2.4e-11 42.9 0.1 8.3e-11 41.2 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBK22889.2 - 5.3e-08 32.5 0.0 7e-07 28.8 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK22889.2 - 3.8e-06 26.8 0.0 6.6e-05 22.8 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2522 PF10747.4 CBK22889.2 - 0.0019 18.2 2.0 0.003 17.6 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2522) Peptidase_M3_N PF08439.5 CBK22889.2 - 0.005 16.8 0.7 0.37 10.8 0.2 3.0 2 0 0 2 2 2 1 Oligopeptidase F S_100 PF01023.14 CBK22889.2 - 0.032 13.5 0.2 0.47 9.8 0.0 2.5 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Arch_ATPase PF01637.13 CBK22889.2 - 0.041 13.5 2.8 1.3 8.7 0.0 3.3 3 1 0 3 3 3 0 Archaeal ATPase Ribosomal_S26e PF01283.14 CBK22890.2 - 2.6e-44 150.1 7.7 2.9e-44 149.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 CBK22890.2 - 0.0005 20.4 0.9 0.02 15.2 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP19 PF01922.12 CBK22890.2 - 0.0069 16.9 0.4 0.0095 16.4 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein Fer4_6 PF12837.2 CBK22890.2 - 0.017 14.9 3.0 0.059 13.2 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBK22890.2 - 0.019 14.7 0.8 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain RNA_pol_N PF01194.12 CBK22890.2 - 0.033 14.1 2.0 0.072 13.1 1.4 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.4 CBK22890.2 - 0.034 13.2 0.7 0.085 11.9 0.5 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Fer4_19 PF06902.6 CBK22890.2 - 0.06 13.1 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 CBK22890.2 - 0.07 12.7 3.5 0.087 12.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 CBK22890.2 - 0.37 10.8 4.1 0.49 10.4 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 CBK22890.2 - 0.6 10.1 4.1 2.6 8.1 2.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK22890.2 - 1.2 9.4 5.5 3.1 8.1 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK22890.2 - 5.4 7.6 8.5 1.8 9.0 2.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain MAP65_ASE1 PF03999.7 CBK22891.2 - 1.8e-06 26.8 6.8 2.3e-06 26.5 4.7 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MAP65_ASE1 PF03999.7 CBK22892.2 - 5.5e-14 51.7 3.3 6.6e-14 51.4 2.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) CALCOCO1 PF07888.6 CBK22892.2 - 0.0018 16.6 1.7 0.0021 16.4 1.2 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cor1 PF04803.7 CBK22892.2 - 0.01 15.6 2.4 2.1 8.1 0.3 2.6 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region Hemagglutinin PF00509.13 CBK22892.2 - 0.015 13.4 0.6 0.02 13.0 0.4 1.2 1 0 0 1 1 1 0 Haemagglutinin DUF550 PF04447.7 CBK22892.2 - 0.042 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Baculo_PEP_C PF04513.7 CBK22892.2 - 0.064 13.0 3.3 0.042 13.6 1.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GreA_GreB_N PF03449.10 CBK22892.2 - 0.11 12.5 0.5 18 5.5 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF4404 PF14357.1 CBK22892.2 - 0.29 11.5 2.0 2.1 8.8 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) ATP-synt_C PF00137.16 CBK22893.2 - 5.3e-25 87.1 18.4 1.4e-14 53.7 6.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C QueT PF06177.6 CBK22893.2 - 8.5 6.3 10.8 1.4 8.8 0.2 3.0 2 1 0 3 3 3 0 QueT transporter YEATS PF03366.11 CBK22894.2 - 1.8e-27 94.8 0.1 2.3e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 YEATS family Fe_hyd_SSU PF02256.12 CBK22894.2 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Iron hydrogenase small subunit UCH PF00443.24 CBK22895.2 - 9.4e-48 162.6 0.0 1.2e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK22895.2 - 4.3e-13 49.3 0.0 9.9e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBK22895.2 - 0.08 12.2 0.1 0.4 9.9 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ubiquitin PF00240.18 CBK22895.2 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DKCLD PF08068.7 CBK22896.2 - 6.1e-31 106.1 0.9 1e-29 102.2 0.1 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain PUA PF01472.15 CBK22896.2 - 4.5e-21 74.3 1.7 9.5e-21 73.3 1.2 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 CBK22896.2 - 6.7e-21 75.0 7.9 4.6e-20 72.2 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) SET PF00856.23 CBK22896.2 - 0.014 15.6 0.2 0.019 15.3 0.1 1.4 1 0 0 1 1 1 0 SET domain GAGA_bind PF06217.7 CBK22896.2 - 8.3 6.2 24.6 13 5.6 17.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family zf-H2C2_2 PF13465.1 CBK22897.2 - 4.2e-25 86.7 37.8 5.1e-07 29.6 0.3 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CBK22897.2 - 5e-24 83.1 41.3 1e-06 28.7 1.3 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK22897.2 - 2e-23 80.9 33.7 2.8e-05 24.1 0.4 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.7 CBK22897.2 - 3.7e-06 26.9 18.6 0.00051 20.1 0.1 4.0 2 1 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBK22897.2 - 6e-06 26.2 27.0 0.041 14.1 0.8 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-TRAF PF02176.13 CBK22897.2 - 3.3e-05 24.1 18.2 0.11 12.9 1.9 3.4 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 CBK22897.2 - 0.00011 22.2 30.2 0.11 12.7 0.6 5.6 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CBK22897.2 - 0.0078 15.9 0.8 0.0078 15.9 0.5 4.6 3 1 2 5 5 5 1 BED zinc finger zf-C2H2_6 PF13912.1 CBK22897.2 - 0.023 14.6 2.2 0.023 14.6 1.5 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger GAGA PF09237.6 CBK22897.2 - 0.033 13.7 3.9 1.6 8.4 0.0 3.1 3 1 0 3 3 3 0 GAGA factor Zn_ribbon_recom PF13408.1 CBK22897.2 - 0.079 13.2 17.3 0.29 11.4 1.8 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.2 CBK22897.2 - 0.11 12.6 21.6 1.1 9.3 0.1 4.2 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_L31 PF01197.13 CBK22897.2 - 0.19 11.7 7.4 11 6.0 0.3 4.0 1 1 2 3 3 3 0 Ribosomal protein L31 zf-C2HC_2 PF13913.1 CBK22897.2 - 0.23 11.1 21.7 0.78 9.4 0.1 4.8 4 1 0 4 4 4 0 zinc-finger of a C2HC-type DUF4187 PF13821.1 CBK22897.2 - 0.28 10.7 3.4 6.7 6.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) ROS_MUCR PF05443.6 CBK22897.2 - 0.49 10.1 7.7 0.67 9.7 0.1 3.2 2 2 1 3 3 3 0 ROS/MUCR transcriptional regulator protein Mmp37 PF09139.6 CBK22898.2 - 1.1e-80 271.1 0.0 1.5e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Gon7 PF08738.5 CBK22899.2 - 9.1e-05 22.3 1.2 9.1e-05 22.3 0.8 2.4 2 1 0 2 2 2 1 Gon7 family DUF948 PF06103.6 CBK22899.2 - 0.00083 19.1 2.3 0.0067 16.2 0.1 2.4 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Spc24 PF08286.6 CBK22899.2 - 0.0093 15.6 5.9 0.43 10.2 0.4 2.2 2 1 0 2 2 2 2 Spc24 subunit of Ndc80 IncA PF04156.9 CBK22899.2 - 0.018 14.6 2.6 0.018 14.6 1.8 2.1 1 1 1 2 2 2 0 IncA protein TSC22 PF01166.13 CBK22899.2 - 0.024 14.6 1.8 4.3 7.3 0.1 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family CorA PF01544.13 CBK22899.2 - 0.026 13.5 4.5 0.034 13.1 3.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3573 PF12097.3 CBK22899.2 - 0.028 13.0 0.3 0.028 13.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Caudo_TAP PF02413.12 CBK22899.2 - 0.042 14.0 0.6 0.06 13.5 0.4 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein HR1 PF02185.11 CBK22899.2 - 0.043 13.5 11.4 0.18 11.5 2.5 2.5 2 0 0 2 2 2 0 Hr1 repeat Fmp27_WPPW PF10359.4 CBK22899.2 - 0.044 12.2 8.2 0.47 8.8 1.2 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4446 PF14584.1 CBK22899.2 - 0.055 13.3 0.4 0.055 13.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) NPV_P10 PF05531.7 CBK22899.2 - 0.081 13.1 2.3 9.3 6.5 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3138 PF11336.3 CBK22899.2 - 0.14 10.3 3.5 2.6 6.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF972 PF06156.8 CBK22899.2 - 0.15 12.3 6.8 0.24 11.7 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Transposase_22 PF02994.9 CBK22899.2 - 0.17 10.3 4.8 0.73 8.2 0.2 2.0 1 1 1 2 2 2 0 L1 transposable element TBPIP PF07106.8 CBK22899.2 - 0.2 11.1 6.4 0.9 9.0 0.6 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 CBK22899.2 - 0.21 10.7 2.0 0.49 9.5 0.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein RasGAP_C PF03836.10 CBK22899.2 - 0.26 10.9 11.1 0.28 10.8 1.0 2.1 1 1 1 2 2 2 0 RasGAP C-terminus Prefoldin PF02996.12 CBK22899.2 - 0.44 10.2 4.3 1.8 8.2 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit ATG16 PF08614.6 CBK22899.2 - 0.56 10.0 10.8 0.65 9.7 0.7 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 CBK22899.2 - 0.71 9.7 13.7 0.55 10.1 1.3 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding MbeD_MobD PF04899.7 CBK22899.2 - 0.84 9.5 10.4 0.31 10.9 1.3 2.4 2 0 0 2 2 2 0 MbeD/MobD like FlxA PF14282.1 CBK22899.2 - 0.88 9.5 17.5 2.6 8.0 2.8 2.9 2 2 0 2 2 2 0 FlxA-like protein Striatin PF08232.7 CBK22899.2 - 1.7 8.9 12.9 4e+02 1.2 8.9 2.1 1 1 0 1 1 1 0 Striatin family GAS PF13851.1 CBK22899.2 - 1.9 7.6 8.5 1.2 8.2 0.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EMP24_GP25L PF01105.19 CBK22899.2 - 2.4 7.8 8.6 0.63 9.7 2.1 2.0 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2968 PF11180.3 CBK22899.2 - 3.5 6.9 10.7 6 6.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.10 CBK22899.2 - 4 6.9 10.9 2.4 7.6 0.4 3.1 1 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 CBK22899.2 - 4.6 7.5 8.5 5.7 7.3 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF904) Enkurin PF13864.1 CBK22899.2 - 5.3 7.3 9.8 19 5.5 1.8 2.5 1 1 1 2 2 2 0 Calmodulin-binding SlyX PF04102.7 CBK22899.2 - 5.8 7.3 12.5 1.4 9.3 0.8 3.0 2 2 0 2 2 2 0 SlyX Cep57_MT_bd PF06657.8 CBK22899.2 - 7.2 6.6 10.2 14 5.6 0.9 2.8 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.3 CBK22899.2 - 8.8 6.2 7.8 15 5.4 1.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WASH_WAHD PF11945.3 CBK22900.2 - 0.0014 18.0 0.1 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF4298 PF14131.1 CBK22900.2 - 0.11 12.4 0.3 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Ribosomal_L11_N PF03946.9 CBK22901.2 - 5.5e-14 51.3 0.2 9e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBK22901.2 - 3.9e-12 46.1 0.0 6.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Rib_5-P_isom_A PF06026.9 CBK22901.2 - 0.086 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) STIL_N PF15253.1 CBK22901.2 - 0.15 10.7 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus RNA_pol_Rpb8 PF03870.10 CBK22902.2 - 2.8e-41 140.9 1.0 3.2e-41 140.7 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_L31e PF01198.14 CBK22903.2 - 7e-31 105.7 0.2 8.9e-31 105.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e PPTA PF01239.17 CBK22904.2 - 6.5e-08 31.6 2.8 0.00093 18.4 0.1 3.3 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat C2 PF00168.25 CBK22905.2 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain RRM_6 PF14259.1 CBK22907.2 - 2.3e-09 37.1 0.0 5.2e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK22907.2 - 1.5e-05 24.5 0.0 4.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 CBK22907.2 - 0.19 11.3 1.9 0.41 10.3 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S9 PF00380.14 CBK22908.2 - 4.4e-35 120.5 0.4 5e-35 120.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 CBK22908.2 - 0.034 11.6 0.0 0.039 11.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Adaptin_N PF01602.15 CBK22910.2 - 2.2e-43 148.3 10.6 3e-43 147.9 7.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DUF1368 PF07112.6 CBK22911.2 - 0.069 11.7 0.5 0.09 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Inhibitor_I29 PF08246.7 CBK22913.2 - 0.07 13.4 0.3 0.2 11.9 0.2 1.9 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Peptidase_S21 PF00716.12 CBK22913.2 - 0.14 11.4 7.7 0.22 10.7 5.4 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) PAT1 PF09770.4 CBK22913.2 - 3.5 5.7 36.9 4.2 5.4 25.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GRIM-19 PF06212.7 CBK22914.2 - 4.1e-32 110.6 0.1 4.8e-32 110.3 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein dCMP_cyt_deam_2 PF08211.6 CBK22915.2 - 1.1e-19 70.6 0.0 6.7e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.17 CBK22915.2 - 7.1e-13 48.0 0.0 3.5e-12 45.8 0.1 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region OTT_1508_deam PF14441.1 CBK22915.2 - 0.00067 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase Seryl_tRNA_N PF02403.17 CBK22916.2 - 0.045 13.7 14.9 0.48 10.4 0.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Streptin-Immun PF11083.3 CBK22916.2 - 0.43 10.6 3.7 9.1 6.3 0.3 2.7 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein Cortex-I_coil PF09304.5 CBK22916.2 - 0.48 10.4 17.0 0.63 10.1 2.3 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil APG6 PF04111.7 CBK22916.2 - 0.49 9.3 21.4 0.11 11.5 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 CBK22916.2 - 0.57 8.7 17.0 1.9 7.0 1.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.6 CBK22916.2 - 2.1 8.0 12.0 0.42 10.3 1.2 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YlqD PF11068.3 CBK22916.2 - 2.7 8.0 18.3 1.5e+02 2.4 6.9 2.7 1 1 1 2 2 2 0 YlqD protein ADIP PF11559.3 CBK22916.2 - 3 7.7 17.3 7.1 6.5 3.9 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CCDC-167 PF15188.1 CBK22916.2 - 3.4 7.6 12.6 16 5.5 1.9 3.8 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 CBK22916.2 - 4 6.5 16.7 0.73 8.9 8.0 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 CBK22916.2 - 5.7 7.3 9.4 0.72 10.2 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 CBK22916.2 - 7.1 6.4 9.2 1.5 8.6 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 CBK22916.2 - 7.6 7.0 13.4 4.1 7.8 0.6 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UQ_con PF00179.21 CBK22917.2 - 1.4e-37 128.2 0.0 1.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK22917.2 - 0.00021 21.0 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK22917.2 - 0.024 14.5 0.1 0.036 13.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.21 CBK22918.2 - 1.8e-43 147.2 0.1 2e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBK22918.2 - 0.049 13.5 0.1 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 CBK22918.2 - 0.18 11.5 0.4 0.35 10.5 0.3 1.5 1 1 0 1 1 1 0 UEV domain CSD PF00313.17 CBK22919.2 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain YozD PF14162.1 CBK22919.2 - 0.046 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 YozD-like protein MatE PF01554.13 CBK22920.2 - 3.8e-26 91.6 31.0 3.2e-18 65.8 3.0 3.5 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.1 CBK22920.2 - 3.4e-05 23.6 9.3 3.4e-05 23.6 6.4 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain RNA_pol_Rpb1_5 PF04998.12 CBK22921.2 - 1e-91 307.0 0.0 1.5e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CBK22921.2 - 2.9e-75 253.6 0.1 4.9e-75 252.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CBK22921.2 - 6.6e-68 227.8 0.0 2.2e-67 226.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBK22921.2 - 1.1e-33 116.2 0.0 2.7e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBK22921.2 - 1.4e-27 95.5 0.0 1.4e-27 95.5 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Macoilin PF09726.4 CBK22921.2 - 0.44 8.7 3.7 0.65 8.2 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 CBK22921.2 - 0.82 7.4 13.2 1.1 6.9 9.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_S13_N PF08069.7 CBK22925.2 - 1.8e-28 98.1 1.9 2.9e-28 97.4 0.1 2.1 3 0 0 3 3 3 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBK22925.2 - 6.4e-23 80.3 0.2 1e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 zf-CCHC PF00098.18 CBK22926.2 - 1.7e-58 191.8 57.6 7.6e-10 38.2 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CBK22926.2 - 1e-14 53.7 42.4 0.0042 16.5 1.0 7.1 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CBK22926.2 - 3.1e-12 46.0 40.3 0.027 14.1 0.1 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 CBK22926.2 - 6.8e-10 38.4 42.9 0.024 14.2 0.6 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 CBK22926.2 - 6e-07 29.0 51.5 0.0017 17.9 0.8 7.1 5 2 2 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.1 CBK22926.2 - 2.1 7.9 53.6 0.21 11.1 2.1 7.1 5 1 2 7 7 7 0 GAG-polyprotein viral zinc-finger DUF747 PF05346.6 CBK22927.2 - 0.076 12.0 2.4 0.089 11.8 1.7 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family YniB PF14002.1 CBK22927.2 - 0.33 10.3 3.1 1.3 8.4 0.8 2.1 2 0 0 2 2 2 0 YniB-like protein zf-DHHC PF01529.15 CBK22927.2 - 6.5 6.1 6.8 7.9 5.8 4.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase CDP-OH_P_transf PF01066.16 CBK22928.2 - 2.5e-19 69.4 7.3 2.5e-19 69.4 5.0 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HSP70 PF00012.15 CBK22929.2 - 2.6e-84 283.2 0.0 1.5e-70 237.7 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK22929.2 - 8.5e-12 44.2 0.0 1.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.6 CBK22929.2 - 0.05 12.5 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 StbA protein DDR PF08841.5 CBK22929.2 - 0.1 11.3 0.0 9.5 4.9 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBK22929.2 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PH PF00169.24 CBK22930.2 - 0.00015 21.9 0.0 0.00026 21.1 0.0 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CBK22930.2 - 0.0076 16.4 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosomal_L22 PF00237.14 CBK22932.2 - 1e-28 99.3 0.1 1.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Rad51 PF08423.6 CBK22933.2 - 6.2e-132 438.1 0.0 1e-131 437.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK22933.2 - 3.7e-15 55.8 0.0 5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK22933.2 - 2.8e-11 43.0 0.1 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBK22933.2 - 5.7e-07 29.6 0.5 1.4e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBK22933.2 - 6.5e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBK22933.2 - 0.00012 21.0 0.0 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CBK22933.2 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein AAA PF00004.24 CBK22933.2 - 0.085 13.0 0.0 0.49 10.5 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK22933.2 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cir_Bir_Yir PF06022.6 CBK22934.2 - 0.18 11.0 1.7 0.28 10.3 1.2 1.3 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir SopD PF11047.3 CBK22934.2 - 0.19 10.6 0.1 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Salmonella outer protein D Rad51 PF08423.6 CBK22936.2 - 6.2e-132 438.1 0.0 1e-131 437.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK22936.2 - 3.7e-15 55.8 0.0 5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK22936.2 - 2.8e-11 43.0 0.1 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBK22936.2 - 5.7e-07 29.6 0.5 1.4e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBK22936.2 - 6.5e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBK22936.2 - 0.00012 21.0 0.0 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CBK22936.2 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein AAA PF00004.24 CBK22936.2 - 0.085 13.0 0.0 0.49 10.5 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK22936.2 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CBK22938.2 - 7.7e-73 244.8 0.0 9.8e-73 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22938.2 - 2.2e-28 99.0 0.0 3e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK22938.2 - 0.0018 17.2 0.0 0.025 13.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBK22938.2 - 0.0035 17.1 0.1 0.0063 16.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 CBK22939.2 - 1.6e-09 37.5 0.2 1.7e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.17 CBK22940.2 - 9.1e-26 90.1 0.0 1.1e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK22940.2 - 9.3e-08 32.5 0.0 1.1e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK22940.2 - 0.00093 18.4 0.0 0.00098 18.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family vATP-synt_E PF01991.13 CBK22941.2 - 1.9e-48 164.4 4.1 2.2e-48 164.1 2.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OmpH PF03938.9 CBK22941.2 - 8.8 6.2 22.2 14 5.5 15.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) P16-Arc PF04699.9 CBK22942.2 - 7.5e-10 39.0 0.0 9.2e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 CBK22942.2 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 1 1 2 2 2 0 Dip2/Utp12 Family RNA_helicase PF00910.17 CBK22943.2 - 6e-09 36.0 0.1 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CBK22943.2 - 0.0054 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBK22943.2 - 0.053 13.2 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 CBK22943.2 - 0.097 12.8 0.1 0.36 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK22943.2 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Exotox-A_cataly PF09009.5 CBK22944.2 - 0.0087 14.9 0.2 0.016 14.1 0.2 1.3 1 0 0 1 1 1 1 Exotoxin A catalytic Yae1_N PF09811.4 CBK22945.2 - 0.00068 19.1 3.4 0.0013 18.2 2.3 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal GBP PF02263.14 CBK22946.2 - 1.3e-22 80.0 0.0 1.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain CobD_Cbib PF03186.8 CBK22947.2 - 1.9 7.5 4.6 0.45 9.5 0.6 1.7 2 0 0 2 2 2 0 CobD/Cbib protein DUF2910 PF11139.3 CBK22947.2 - 3.4 6.7 9.3 2 7.5 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2910) DUF1032 PF06278.6 CBK22948.2 - 2.2e-22 79.2 0.2 2.3e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1032) ScpA_ScpB PF02616.9 CBK22948.2 - 0.0043 16.6 1.2 0.0051 16.4 0.9 1.1 1 0 0 1 1 1 1 ScpA/B protein MRP-L20 PF12824.2 CBK22948.2 - 0.032 14.1 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Ribosomal_L4 PF00573.17 CBK22949.2 - 3e-43 147.4 0.2 5.3e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBK22949.2 - 9.6e-22 76.6 4.4 1.1e-21 76.4 2.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L2_C PF03947.13 CBK22950.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK22950.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RIO1 PF01163.17 CBK22951.2 - 1.9e-47 161.0 0.1 1.9e-47 161.0 0.1 2.5 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 CBK22951.2 - 3.9e-24 84.5 0.2 1.3e-23 82.7 0.1 2.0 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CBK22951.2 - 9.8e-10 38.5 0.2 0.00023 20.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBK22951.2 - 1.2e-07 31.0 0.1 7.5e-06 25.1 0.0 2.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK22951.2 - 0.34 10.4 0.0 0.34 10.4 0.0 2.5 2 1 0 2 2 2 0 Choline/ethanolamine kinase MIG-14_Wnt-bd PF06664.7 CBK22952.2 - 0.0049 15.7 4.1 0.0051 15.6 2.9 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion MARVEL PF01284.18 CBK22952.2 - 0.011 15.5 0.9 0.012 15.4 0.7 1.1 1 0 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.7 CBK22952.2 - 0.014 14.9 2.4 0.017 14.6 1.7 1.1 1 0 0 1 1 1 0 SUR7/PalI family PIRT PF15099.1 CBK22952.2 - 0.024 13.8 0.7 0.026 13.7 0.5 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family OPT PF03169.10 CBK22952.2 - 0.029 12.8 2.5 0.032 12.6 1.8 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein CoA_binding_3 PF13727.1 CBK22952.2 - 0.029 14.2 1.6 0.031 14.0 1.1 1.1 1 0 0 1 1 1 0 CoA-binding domain DUF485 PF04341.7 CBK22952.2 - 0.031 13.9 1.9 0.043 13.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 7tm_7 PF08395.7 CBK22952.2 - 0.036 13.0 3.4 0.041 12.9 2.4 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF2569 PF10754.4 CBK22952.2 - 0.044 14.0 5.0 0.046 13.9 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) PMP22_Claudin PF00822.15 CBK22952.2 - 0.049 13.2 0.7 0.052 13.2 0.5 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF4231 PF14015.1 CBK22952.2 - 0.079 12.9 0.7 0.093 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2663 PF10864.3 CBK22952.2 - 0.079 13.1 0.8 0.087 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF3816 PF12822.2 CBK22952.2 - 0.097 12.5 5.7 0.11 12.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF2207 PF09972.4 CBK22952.2 - 0.13 10.8 2.4 0.14 10.7 1.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.6 CBK22952.2 - 0.13 11.5 2.4 0.14 11.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF962 PF06127.6 CBK22952.2 - 0.59 10.0 3.3 0.9 9.4 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF843 PF05814.6 CBK22952.2 - 0.6 9.9 4.3 0.86 9.4 2.9 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Dispanin PF04505.7 CBK22952.2 - 1.2 8.6 4.2 2.2 7.8 0.2 2.7 1 1 2 3 3 3 0 Interferon-induced transmembrane protein DUF2583 PF10762.4 CBK22952.2 - 1.5 9.0 4.6 4.9 7.3 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) SdpI PF13630.1 CBK22952.2 - 1.5 8.5 8.7 2.7 7.7 6.0 1.4 1 1 0 1 1 1 0 SdpI/YhfL protein family DUF2628 PF10947.3 CBK22952.2 - 2.1 8.1 5.6 2.8 7.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF307 PF03733.8 CBK22952.2 - 3 8.3 6.2 8.9 6.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF307) PfkB PF00294.19 CBK22953.2 - 8.5e-31 107.1 0.0 1e-29 103.6 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SIS PF01380.17 CBK22953.2 - 3.4e-16 59.0 0.0 6.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 CBK22953.2 - 8.2e-08 32.0 0.1 0.00047 19.8 0.0 2.3 1 1 1 2 2 2 2 SIS domain PAF-AH_p_II PF03403.8 CBK22953.2 - 0.043 12.1 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF563 PF04577.9 CBK22954.2 - 5.7e-20 72.1 0.2 7e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.20 CBK22955.2 - 2.7e-37 128.3 0.0 3.3e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK22955.2 - 1.1e-20 73.7 0.0 3.3e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBK22955.2 - 0.11 11.7 0.2 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Peptidase_S9_N PF02897.10 CBK22956.2 - 1.3e-22 79.9 1.2 7.1e-22 77.5 0.4 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBK22956.2 - 1.6e-19 70.0 0.0 3.7e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBK22956.2 - 0.0096 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family HSP70 PF00012.15 CBK22957.2 - 2e-61 207.7 0.0 2.4e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22957.2 - 2.1e-10 39.7 0.0 4.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 CBK22957.2 - 0.00044 20.0 0.1 0.63 9.8 0.0 3.6 3 1 0 3 3 3 1 Cell division protein FtsA StbA PF06406.6 CBK22957.2 - 0.11 11.4 0.0 0.79 8.6 0.0 2.0 1 1 1 2 2 2 0 StbA protein CP_ATPgrasp_1 PF04174.8 CBK22957.2 - 0.15 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Fe-ADH PF00465.14 CBK22958.2 - 5.7e-70 235.7 0.0 6.9e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK22958.2 - 1.5e-09 37.5 0.1 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CbiK PF06180.6 CBK22958.2 - 0.019 14.0 0.1 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) tRNA-synt_2b PF00587.20 CBK22959.2 - 5e-61 205.2 0.0 8.4e-61 204.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK22959.2 - 1.6e-17 63.1 1.6 2.6e-17 62.5 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain WHEP-TRS PF00458.15 CBK22959.2 - 5.1e-11 42.0 8.4 1.1e-10 40.9 5.8 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Ribonuc_red_lgC PF02867.10 CBK22960.2 - 1.4e-09 37.1 0.0 0.0024 16.5 0.0 3.2 2 1 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBK22960.2 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain TIM PF00121.13 CBK22961.2 - 1.1e-87 293.1 0.2 1.3e-87 292.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.19 CBK22961.2 - 0.0015 17.8 0.1 0.0034 16.6 0.1 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel IGPS PF00218.16 CBK22961.2 - 0.0021 17.1 0.1 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase WD40 PF00400.27 CBK22962.2 - 8.1e-68 222.0 36.8 2.1e-09 36.8 0.0 13.5 14 0 0 14 14 14 11 WD domain, G-beta repeat eIF2A PF08662.6 CBK22962.2 - 1.7e-05 24.6 0.1 0.036 13.7 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBK22962.2 - 0.0052 14.9 2.0 2.6 6.0 0.0 4.7 5 1 1 6 6 6 1 Nucleoporin Nup120/160 Imm15 PF15590.1 CBK22962.2 - 0.15 11.1 0.0 0.38 9.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 15 U3_assoc_6 PF08640.6 CBK22963.2 - 7.9e-23 80.0 4.2 1.6e-22 79.0 0.3 2.6 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CBK22963.2 - 0.00076 18.4 1.3 0.1 11.4 0.1 2.3 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 CBK22963.2 - 0.0024 17.6 0.0 0.026 14.2 0.0 2.1 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) TPR_12 PF13424.1 CBK22964.2 - 0.046 13.6 1.2 0.081 12.8 0.8 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 CBK22965.2 - 1.6e-26 91.0 41.8 7.5e-06 25.9 0.9 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK22965.2 - 1.8e-20 71.6 37.6 0.0007 19.7 0.1 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK22965.2 - 1.9e-17 62.6 34.8 0.0013 18.8 2.5 7.4 7 0 0 7 7 7 6 Zinc-finger double domain zf-met PF12874.2 CBK22965.2 - 9e-05 22.5 24.9 0.31 11.3 0.6 6.4 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBK22965.2 - 0.00073 19.6 0.4 0.00073 19.6 0.3 6.7 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding PhnA_Zn_Ribbon PF08274.7 CBK22965.2 - 0.05 13.3 1.3 3.7 7.4 0.0 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_2 PF12756.2 CBK22965.2 - 0.11 12.6 0.3 0.11 12.6 0.2 4.5 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CBK22965.2 - 0.12 12.3 23.3 3.2 7.8 0.2 6.0 6 0 0 6 6 6 0 C2H2-type zinc finger DUF555 PF04475.7 CBK22965.2 - 0.17 11.8 0.0 0.85 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF555) zf-Di19 PF05605.7 CBK22965.2 - 0.59 10.3 27.0 0.11 12.6 1.9 4.3 1 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 CBK22965.2 - 1.7 8.3 0.0 1.7 8.3 0.0 4.2 6 0 0 6 6 5 0 XPA protein N-terminal AAA PF00004.24 CBK22966.2 - 8.9e-99 326.8 0.0 3.7e-48 163.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CBK22966.2 - 2.6e-17 62.5 0.8 7.1e-17 61.1 0.5 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CBK22966.2 - 8.3e-15 54.4 0.0 8.7e-07 28.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBK22966.2 - 8.3e-14 51.8 0.0 1.1e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBK22966.2 - 3.6e-13 49.7 0.3 3e-05 24.1 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK22966.2 - 2.5e-12 47.1 0.0 3e-05 24.0 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CBK22966.2 - 3.2e-12 46.5 0.0 4e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBK22966.2 - 1.1e-11 44.5 0.1 8.8e-06 25.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBK22966.2 - 2.7e-11 44.3 0.0 5.5e-05 23.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CBK22966.2 - 3.4e-10 39.9 0.0 0.00013 21.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBK22966.2 - 2.4e-09 36.5 0.0 0.00046 19.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 CBK22966.2 - 5e-08 32.0 0.0 0.00085 18.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 CBK22966.2 - 1.8e-07 31.1 0.1 0.0029 17.3 0.1 3.5 2 2 2 4 4 4 2 Archaeal ATPase Vps4_C PF09336.5 CBK22966.2 - 2e-07 30.7 0.1 1.8e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 CBK22966.2 - 2.5e-07 30.8 0.0 0.009 16.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CBK22966.2 - 4.4e-07 30.2 0.0 0.0083 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBK22966.2 - 5.6e-07 29.1 0.1 0.052 12.9 0.0 3.1 2 1 1 3 3 3 2 IstB-like ATP binding protein CDC48_2 PF02933.12 CBK22966.2 - 8.1e-07 28.5 0.1 4.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 CBK22966.2 - 8.4e-07 28.3 0.5 0.047 12.8 0.0 2.9 4 0 0 4 4 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CBK22966.2 - 1.6e-06 28.1 0.0 0.032 14.2 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 CBK22966.2 - 1.7e-06 27.6 0.4 0.021 14.5 0.2 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 CBK22966.2 - 1.7e-06 27.5 2.6 1.4 8.2 0.0 4.0 2 2 2 4 4 4 3 AAA domain NACHT PF05729.7 CBK22966.2 - 4e-06 26.5 0.0 0.23 11.0 0.0 4.0 3 1 0 4 4 4 2 NACHT domain ResIII PF04851.10 CBK22966.2 - 6e-06 26.2 0.0 0.0034 17.2 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CBK22966.2 - 1.4e-05 25.4 0.0 0.79 10.0 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_28 PF13521.1 CBK22966.2 - 1.4e-05 25.0 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBK22966.2 - 2.2e-05 24.0 0.0 0.22 11.0 0.0 3.8 2 2 1 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.1 CBK22966.2 - 2.3e-05 24.1 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CBK22966.2 - 3e-05 23.6 0.0 0.0084 15.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CBK22966.2 - 7.6e-05 21.7 0.0 0.3 9.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Bac_DnaA PF00308.13 CBK22966.2 - 8.8e-05 22.2 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein Molydop_binding PF01568.16 CBK22966.2 - 0.00014 21.6 0.0 0.00042 20.0 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain KaiC PF06745.8 CBK22966.2 - 0.00018 20.6 1.3 0.83 8.7 0.0 3.8 4 1 1 5 5 3 1 KaiC NTPase_1 PF03266.10 CBK22966.2 - 0.00021 21.0 1.7 1.3 8.7 0.0 4.6 4 1 1 5 5 5 1 NTPase DUF815 PF05673.8 CBK22966.2 - 0.00022 20.2 0.0 0.16 10.8 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CBK22966.2 - 0.00027 19.9 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Cytidylate_kin2 PF13189.1 CBK22966.2 - 0.00045 20.1 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 CBK22966.2 - 0.001 18.7 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CBK22966.2 - 0.0012 18.1 0.1 2 7.6 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein UFD1 PF03152.9 CBK22966.2 - 0.0043 16.2 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2075 PF09848.4 CBK22966.2 - 0.011 14.7 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CBK22966.2 - 0.011 15.3 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CBK22966.2 - 0.014 14.9 0.1 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CBK22966.2 - 0.016 15.0 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.10 CBK22966.2 - 0.029 13.0 0.0 0.34 9.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBK22966.2 - 0.032 13.6 0.8 7.5 5.8 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 CBK22966.2 - 0.043 12.7 0.0 11 4.8 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 CBK22966.2 - 0.056 12.4 0.1 12 4.7 0.0 3.2 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 CBK22966.2 - 0.066 12.6 0.1 8.5 5.7 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 CBK22966.2 - 0.078 12.5 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBK22966.2 - 0.088 12.2 0.0 3.4 7.1 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 CBK22966.2 - 0.1 11.5 0.0 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.5 CBK22966.2 - 0.11 11.7 0.0 12 5.0 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CBK22966.2 - 0.11 12.0 0.0 5.8 6.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pro_isomerase PF00160.16 CBK22967.2 - 2.4e-49 167.5 0.5 3.2e-49 167.1 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.15 CBK22968.2 - 5.2e-21 73.9 1.3 5.2e-21 73.9 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBK22968.2 - 2e-05 24.5 12.2 4.3e-05 23.4 8.5 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Nucleoporin2 PF04096.9 CBK22970.2 - 1.4e-19 70.2 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase HSP20 PF00011.16 CBK22971.2 - 1.4e-18 66.5 0.0 2.1e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Amidohydro_1 PF01979.15 CBK22972.2 - 3.4e-10 40.1 0.0 4.2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBK22972.2 - 2.8e-08 33.4 0.0 4.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CBK22972.2 - 0.0091 16.0 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBK22973.2 - 1.2e-33 117.1 2.6 1.4e-33 116.9 1.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBK22973.2 - 2.2e-13 50.2 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CBK22973.2 - 3.2e-12 47.0 0.1 4e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 CBK22973.2 - 0.024 13.5 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase DUF2450 PF10475.4 CBK22974.2 - 0.021 13.7 0.1 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Snapin_Pallidin PF14712.1 CBK22974.2 - 0.38 11.0 4.3 0.71 10.2 0.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Vps54 PF07928.7 CBK22975.2 - 1.5e-25 89.9 0.9 1.5e-25 89.9 0.7 2.0 2 0 0 2 2 2 1 Vps54-like protein LRR_8 PF13855.1 CBK22977.2 - 0.048 13.4 12.5 0.72 9.6 0.6 4.7 4 2 0 4 4 4 0 Leucine rich repeat Trypan_PARP PF05887.6 CBK22977.2 - 1.3 8.7 14.3 0.19 11.5 6.7 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DNA_pol_B_2 PF03175.8 CBK22978.2 - 5.7e-08 31.8 9.7 0.001 17.7 0.1 3.6 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral hSac2 PF12456.3 CBK22979.2 - 0.0001 21.6 0.4 0.0022 17.3 0.0 3.0 1 1 2 3 3 3 1 Inositol phosphatase LRR_8 PF13855.1 CBK22979.2 - 0.00024 20.8 8.5 0.46 10.2 0.3 4.6 4 2 1 5 5 5 3 Leucine rich repeat Trypan_PARP PF05887.6 CBK22979.2 - 0.0025 17.6 12.9 0.0039 17.0 9.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 CBK22979.2 - 0.0036 16.5 12.6 0.0036 16.5 8.7 2.1 1 1 1 2 2 2 1 Potato leaf roll virus readthrough protein Sialidase PF02973.11 CBK22979.2 - 0.063 12.2 0.4 2.5 7.0 0.0 2.6 2 1 0 2 2 2 0 Sialidase, N-terminal domain LRR_4 PF12799.2 CBK22979.2 - 8 6.2 14.6 68 3.2 0.0 5.3 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) GBP PF02263.14 CBK22980.2 - 3.6e-36 124.5 0.0 4.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MFS_1 PF07690.11 CBK22981.2 - 4.6e-44 150.5 20.5 1.2e-32 113.0 8.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK22981.2 - 3.5e-13 48.9 27.3 9.9e-13 47.4 18.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CBK22981.2 - 8.8e-07 27.4 3.5 8.8e-07 27.4 2.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 CBK22981.2 - 0.0044 16.7 0.2 0.018 14.8 0.1 2.0 1 0 0 1 1 1 1 MFS_1 like family NUC153 PF08159.7 CBK22982.2 - 1.1e-11 44.1 0.5 2.3e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 CBK22982.2 - 0.0036 17.1 0.0 3.5 7.6 0.0 3.0 4 0 0 4 4 4 2 WD domain, G-beta repeat BCDHK_Adom3 PF10436.4 CBK22983.2 - 4.3e-40 136.9 0.0 6.4e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBK22983.2 - 1.3e-16 60.3 0.0 2.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK22983.2 - 0.00076 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PA14_2 PF10528.4 CBK22983.2 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 GLEYA domain Chitin_synth_2 PF03142.10 CBK22985.2 - 8.4e-28 97.0 2.5 3.1e-26 91.8 0.6 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1 PF01644.12 CBK22985.2 - 2.2e-22 79.5 0.1 1.1e-17 64.2 0.0 2.5 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CBK22985.2 - 3e-14 53.2 0.1 6.5e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CBK22985.2 - 1.9e-10 40.9 0.0 5.3e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.1 CBK22986.2 - 2.2e-14 53.3 0.0 1.2e-09 37.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan ATG_C PF09333.6 CBK22987.2 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATG C terminal domain Longin PF13774.1 CBK22987.2 - 0.17 11.4 0.4 0.34 10.4 0.3 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain Chorein_N PF12624.2 CBK22989.2 - 4.5e-38 129.4 1.1 2e-37 127.3 0.8 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter zf-HIT PF04438.11 CBK22993.2 - 2e-11 43.3 9.3 2e-11 43.3 6.5 1.5 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.19 CBK22993.2 - 0.34 10.8 10.9 0.48 10.3 7.5 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 CBK22993.2 - 4.2 7.4 11.1 5.9 6.9 7.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCM PF00493.18 CBK22994.2 - 1.4e-130 434.9 0.1 2e-130 434.4 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBK22994.2 - 1.1e-17 64.6 0.1 3e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBK22994.2 - 5.3e-08 32.2 0.0 2.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBK22994.2 - 5.2e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBK22994.2 - 0.0043 16.5 0.1 2 7.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 CBK22994.2 - 0.017 14.7 0.0 0.15 11.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_binding_2 PF03446.10 CBK22995.2 - 9.3e-26 90.6 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.14 CBK22995.2 - 9.1e-22 77.6 0.0 1.3e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain IlvN PF07991.7 CBK22995.2 - 0.0032 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain zf-primase PF09329.6 CBK22996.2 - 8.8e-13 47.6 2.6 9.7e-13 47.5 0.5 2.0 2 0 0 2 2 2 1 Primase zinc finger tRNA_anti-codon PF01336.20 CBK22996.2 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain T-box PF00907.17 CBK22996.2 - 0.067 12.6 0.2 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 T-box HSP70 PF00012.15 CBK22997.2 - 1.2e-85 287.7 0.6 1.5e-85 287.3 0.4 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK22997.2 - 4e-11 42.0 0.6 1.3e-07 30.5 0.1 3.1 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBK22997.2 - 9.7e-06 24.7 0.2 0.13 11.2 0.1 2.4 1 1 1 2 2 2 2 StbA protein DDR PF08841.5 CBK22997.2 - 0.00022 20.1 0.0 0.12 11.1 0.0 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBK22997.2 - 0.0031 16.6 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FtsA PF14450.1 CBK22997.2 - 0.0095 15.7 4.2 1.8 8.4 0.0 3.9 3 1 0 3 3 3 1 Cell division protein FtsA BcrAD_BadFG PF01869.15 CBK22997.2 - 0.081 12.2 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Myc_N PF01056.13 CBK22997.2 - 0.38 9.8 3.3 0.66 9.0 2.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region HATPase_c PF02518.21 CBK22998.2 - 1e-08 34.8 0.1 2.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK22998.2 - 5.7e-08 32.4 0.6 2.4e-07 30.4 0.4 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 CBK22999.2 - 1.8e-12 46.7 0.1 2.1e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CBK23000.2 - 1.9e-32 111.8 0.1 2.4e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DUF805 PF05656.9 CBK23001.2 - 0.029 14.1 1.4 0.042 13.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Pex14_N PF04695.8 CBK23001.2 - 0.066 13.2 0.2 0.066 13.2 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AIF-MLS PF14962.1 CBK23001.2 - 0.089 12.4 0.1 0.089 12.4 0.1 1.7 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Aa_trans PF01490.13 CBK23002.2 - 1.4e-12 46.7 9.8 1.6e-12 46.6 6.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein KbaA PF14089.1 CBK23002.2 - 0.0077 15.7 3.6 0.045 13.2 0.5 2.0 2 0 0 2 2 2 1 KinB-signalling pathway activation in sporulation Polysacc_synt_C PF14667.1 CBK23002.2 - 0.012 15.4 9.3 0.014 15.1 6.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF3433 PF11915.3 CBK23002.2 - 0.085 13.0 1.4 9.1 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) CstA PF02554.9 CBK23002.2 - 0.1 11.2 8.2 0.099 11.2 5.7 1.0 1 0 0 1 1 1 0 Carbon starvation protein CstA Strabismus PF06638.6 CBK23002.2 - 0.12 10.6 1.1 0.14 10.4 0.8 1.1 1 0 0 1 1 1 0 Strabismus protein DUF4181 PF13789.1 CBK23002.2 - 0.14 12.1 4.4 0.18 11.7 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF2545 PF10810.3 CBK23002.2 - 0.45 10.9 7.0 0.92 9.9 4.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2545) DUF3042 PF11240.3 CBK23002.2 - 1.4 8.7 4.2 1.8 8.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Herpes_US9 PF06072.6 CBK23002.2 - 4.5 7.1 5.1 24 4.8 0.2 2.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Aa_trans PF01490.13 CBK23003.2 - 3.9e-37 127.7 24.2 5.9e-36 123.8 16.7 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBK23003.2 - 4e-05 22.6 7.1 6.7e-05 21.8 4.9 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family RWD PF05773.17 CBK23004.2 - 1.7e-14 53.6 1.3 3e-14 52.8 0.9 1.4 1 0 0 1 1 1 1 RWD domain FNIP_M PF14637.1 CBK23004.2 - 0.002 17.7 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain HC2 PF07382.6 CBK23005.2 - 9.2e-24 84.3 63.6 4.9e-07 29.8 3.2 5.1 5 0 0 5 5 5 5 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.6 CBK23005.2 - 0.00034 20.2 22.6 0.015 14.8 0.6 5.5 6 0 0 6 6 6 3 African swine fever virus J13L protein Glyco_hydro_47 PF01532.15 CBK23006.2 - 2.2e-93 313.3 0.1 2.8e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 CBK23007.2 - 9.2e-05 21.7 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBK23008.2 - 8.3e-45 152.9 0.0 9.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23008.2 - 6e-23 81.2 0.0 6.7e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23008.2 - 1.1e-06 27.8 0.0 1.8e-05 23.8 0.0 2.2 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 CBK23008.2 - 0.033 13.9 0.1 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CM_1 PF07736.6 CBK23008.2 - 0.093 12.8 0.1 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 Chorismate mutase type I PAS_10 PF13596.1 CBK23008.2 - 0.093 13.0 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 PAS domain HSP70 PF00012.15 CBK23009.2 - 3.6e-183 609.7 1.2 3.9e-87 292.5 0.0 4.1 4 0 0 4 4 4 4 Hsp70 protein MreB_Mbl PF06723.8 CBK23009.2 - 1.2e-26 93.0 0.1 1.1e-09 37.3 0.0 4.8 3 2 0 4 4 4 4 MreB/Mbl protein DDR PF08841.5 CBK23009.2 - 1e-07 31.1 0.9 0.015 14.1 0.0 4.5 5 0 0 5 5 5 2 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CBK23009.2 - 0.0023 16.9 0.0 2.8 6.7 0.0 2.9 2 0 0 2 2 2 2 StbA protein Cbl_N PF02262.11 CBK23009.2 - 0.0025 17.4 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 2 CBL proto-oncogene N-terminal domain 1 MOZ_SAS PF01853.13 CBK23009.2 - 0.14 11.3 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 MOZ/SAS family Chlam_vir PF05475.6 CBK23009.2 - 1.2 8.1 4.5 14 4.7 0.2 3.3 4 0 0 4 4 4 0 Chlamydia virulence protein PGP3-D RecA PF00154.16 CBK23010.2 - 4.2e-161 535.3 0.2 5.3e-161 535.0 0.1 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 CBK23010.2 - 1.2e-08 34.2 0.2 1.6e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK23010.2 - 1.2e-06 28.0 0.4 4.4e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CBK23010.2 - 2.3e-06 26.8 0.3 2.5e-05 23.5 0.3 2.4 1 1 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 CBK23010.2 - 0.0018 18.0 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 CBK23010.2 - 0.0061 16.8 0.0 0.019 15.2 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 CBK23010.2 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.1 CBK23010.2 - 0.029 13.0 0.0 0.056 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain CobU PF02283.11 CBK23010.2 - 0.043 13.2 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_16 PF13191.1 CBK23010.2 - 0.045 13.7 0.3 0.15 12.0 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 CBK23010.2 - 0.046 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DFP PF04127.10 CBK23010.2 - 0.047 13.3 0.0 7.4 6.1 0.0 3.0 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein AAA PF00004.24 CBK23010.2 - 0.051 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBK23010.2 - 0.07 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.26 CBK23011.2 - 9.7e-24 82.8 0.2 1.3e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CBK23011.2 - 3e-12 45.8 7.8 4.8e-12 45.2 5.4 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 CBK23011.2 - 0.0029 17.1 0.9 0.0056 16.2 0.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBK23011.2 - 0.003 17.1 1.0 0.0057 16.3 0.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Spectrin PF00435.16 CBK23011.2 - 0.076 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Enolase_C PF00113.17 CBK23011.2 - 0.084 11.8 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain CactinC_cactus PF09732.4 CBK23011.2 - 0.087 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein DUF4613 PF15390.1 CBK23012.2 - 4.7 5.2 10.4 5.8 4.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Homeobox_KN PF05920.6 CBK23013.2 - 1.2e-15 56.8 2.3 3.4e-15 55.4 1.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CBK23013.2 - 2.2e-08 33.5 3.7 2.2e-08 33.5 2.6 2.4 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CBK23013.2 - 0.0044 16.0 0.3 0.012 14.6 0.2 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Phage_integrase PF00589.17 CBK23013.2 - 0.58 9.7 6.0 0.087 12.4 0.6 2.1 2 1 0 2 2 2 0 Phage integrase family MT-A70 PF05063.9 CBK23014.2 - 4.2e-35 120.8 0.0 7.4e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 MT-A70 PHD PF00628.24 CBK23014.2 - 5.8e-09 35.5 8.6 9.8e-09 34.7 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK23014.2 - 0.00022 20.4 5.2 0.00047 19.4 3.6 1.5 1 0 0 1 1 1 1 PHD-finger Methyltransf_26 PF13659.1 CBK23014.2 - 0.022 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Prok-RING_1 PF14446.1 CBK23014.2 - 0.3 10.8 5.9 0.75 9.5 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Fer2_BFD PF04324.10 CBK23014.2 - 0.87 9.6 4.8 6.2 6.9 3.3 2.1 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain zf-Sec23_Sec24 PF04810.10 CBK23014.2 - 1.2 8.7 6.3 2.9 7.5 4.3 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Ras PF00071.17 CBK23015.2 - 9.7e-42 142.1 0.2 1.1e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBK23015.2 - 1.3e-10 40.7 0.1 1.6e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBK23015.2 - 6e-07 29.9 0.0 9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBK23015.2 - 0.00097 18.6 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 CBK23016.2 - 3.2e-09 36.3 0.0 3.6e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBK23016.2 - 1.1e-05 24.7 0.0 1.2e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBK23016.2 - 0.0042 17.5 0.0 0.0045 17.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK23016.2 - 0.0063 16.4 0.0 0.0066 16.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CBK23016.2 - 0.026 14.0 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.18 CBK23016.2 - 0.11 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 MCM2/3/5 family G-alpha PF00503.15 CBK23016.2 - 0.11 11.1 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK23016.2 - 0.15 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_transf_5 PF08323.6 CBK23017.2 - 4.5e-30 104.9 0.0 8.6e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CBK23017.2 - 3.1e-13 49.5 0.0 7.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBK23017.2 - 0.015 15.4 0.0 0.1 12.7 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBK23017.2 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain CBM_48 PF02922.13 CBK23018.2 - 0.0001 22.2 0.2 0.00028 20.8 0.1 1.8 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 CBK23019.2 - 0.042 13.2 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain UPF0016 PF01169.14 CBK23021.2 - 3.3e-35 120.0 20.1 1.3e-19 70.0 3.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CBK23021.2 - 0.004 16.6 4.8 0.011 15.2 2.2 2.1 2 0 0 2 2 2 1 Integral membrane protein TerC family LRR_6 PF13516.1 CBK23022.2 - 4.2e-08 32.4 13.6 0.86 9.8 0.0 10.3 12 0 0 12 12 12 3 Leucine Rich repeat LRR_4 PF12799.2 CBK23022.2 - 0.00013 21.4 8.0 0.81 9.3 0.1 7.6 7 4 2 9 9 9 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBK23022.2 - 0.52 10.7 16.8 40 5.0 0.1 8.6 9 0 0 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 CBK23022.2 - 0.89 9.8 17.7 27 5.3 0.2 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat E1-E2_ATPase PF00122.15 CBK23023.2 - 3.2e-19 68.9 0.0 1.2e-18 67.0 0.0 1.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBK23023.2 - 1.7e-12 48.2 0.0 4.4e-11 43.6 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK23023.2 - 2e-10 41.1 0.0 5.9e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK23023.2 - 6.1e-10 38.9 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK23023.2 - 0.0078 15.8 0.1 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_2d PF01409.15 CBK23024.2 - 7.6e-49 166.1 0.0 1.3e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CBK23024.2 - 5.4e-23 80.9 2.3 1.2e-22 79.8 0.1 2.5 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 CBK23024.2 - 0.00016 20.5 1.5 0.065 11.9 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class II (D, K and N) LRR_8 PF13855.1 CBK23025.2 - 0.0015 18.2 5.0 0.16 11.7 0.1 3.9 4 1 0 4 4 4 2 Leucine rich repeat TAXi_C PF14541.1 CBK23026.2 - 1.1e-17 64.0 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 CBK23026.2 - 0.0042 16.3 0.0 0.011 15.0 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Ribonuc_red_lgC PF02867.10 CBK23027.2 - 1.7e-09 36.7 0.0 0.0027 16.3 0.0 3.2 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBK23027.2 - 0.00024 20.8 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain DAGK_cat PF00781.19 CBK23028.2 - 3.4e-19 68.5 0.0 5.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sod_Fe_C PF02777.13 CBK23029.2 - 7.5e-38 128.6 0.3 7.5e-38 128.6 0.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain THF_DHG_CYH_C PF02882.14 CBK23029.2 - 9.4e-31 106.0 0.4 9.4e-31 106.0 0.3 3.1 3 1 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.16 CBK23029.2 - 3.1e-30 104.7 2.2 1.9e-27 95.7 2.8 2.6 2 1 0 2 2 2 1 ThiF family Sod_Fe_N PF00081.17 CBK23029.2 - 1e-28 99.4 0.3 2e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MoeZ_MoeB PF05237.8 CBK23029.2 - 2.5e-14 52.6 1.1 4.1e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain Saccharop_dh PF03435.13 CBK23029.2 - 6.2e-06 25.4 0.0 1.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CBK23029.2 - 0.0006 19.9 0.1 0.0021 18.1 0.1 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBK23029.2 - 0.0027 17.9 0.0 0.0085 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH PF00763.18 CBK23030.2 - 5.4e-27 94.1 0.0 6.1e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF2368 PF10166.4 CBK23030.2 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Ribosomal_S27e PF01667.12 CBK23031.2 - 1.5e-24 85.2 3.2 1.5e-24 85.2 2.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S27 IBR PF01485.16 CBK23031.2 - 0.00046 20.0 2.5 0.00083 19.1 1.8 1.4 1 0 0 1 1 1 1 IBR domain zf-NADH-PPase PF09297.6 CBK23031.2 - 0.084 12.4 0.8 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TF_Zn_Ribbon PF08271.7 CBK23031.2 - 0.16 11.3 2.9 0.31 10.3 2.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-B_box PF00643.19 CBK23031.2 - 1.6 8.7 6.1 3.8 7.4 2.0 2.3 2 1 0 2 2 2 0 B-box zinc finger Mu-like_Com PF10122.4 CBK23031.2 - 3 6.9 7.0 1.4 7.9 0.1 2.9 2 1 1 3 3 3 0 Mu-like prophage protein Com zinc_ribbon_4 PF13717.1 CBK23031.2 - 7.4 6.3 8.3 10 5.9 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain tRNA-synt_2b PF00587.20 CBK23032.2 - 5e-61 205.2 0.0 8.6e-61 204.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK23032.2 - 1.6e-17 63.2 1.4 2.7e-17 62.5 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain WHEP-TRS PF00458.15 CBK23032.2 - 3.6e-08 32.9 6.7 7.9e-08 31.8 4.6 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Steroid_dh PF02544.11 CBK23033.2 - 2.5e-29 101.9 4.0 4.6e-29 101.1 2.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBK23033.2 - 0.0016 17.8 0.7 0.0022 17.3 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.1 CBK23033.2 - 0.005 17.0 0.3 0.009 16.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain PEMT PF04191.8 CBK23033.2 - 0.03 14.4 0.7 0.03 14.4 0.5 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.18 CBK23033.2 - 0.077 12.4 0.8 0.48 9.8 0.5 2.0 1 1 0 1 1 1 0 Ubiquitin family UPF0004 PF00919.15 CBK23034.2 - 2.8e-21 75.1 0.1 5.3e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 CBK23034.2 - 6.5e-20 71.9 0.0 2.2e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.15 CBK23034.2 - 0.094 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 TRAM domain Sugar_tr PF00083.19 CBK23035.2 - 7.2e-49 166.5 37.5 7.4e-35 120.3 17.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBK23035.2 - 3.6e-12 45.6 59.6 4.2e-11 42.1 20.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBK23035.2 - 1.1e-07 30.6 17.0 1.1e-07 30.6 11.8 2.8 1 1 1 3 3 3 1 MFS/sugar transport protein DUF1129 PF06570.6 CBK23035.2 - 0.42 9.9 12.2 0.3 10.3 6.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) VIT1 PF01988.14 CBK23035.2 - 5 6.5 16.4 0.15 11.5 4.5 2.5 2 0 0 2 2 2 0 VIT family DUF4345 PF14248.1 CBK23035.2 - 6.8 6.1 23.3 10 5.5 11.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4345) BPL_LplA_LipB PF03099.14 CBK23036.2 - 2.6e-19 69.4 0.0 4.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family eIF2A PF08662.6 CBK23037.2 - 6.5e-37 127.1 0.0 6.8e-35 120.5 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CBK23037.2 - 7.2e-05 22.5 2.6 0.0046 16.7 0.4 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBK23037.2 - 0.0023 16.8 0.0 0.67 8.6 0.0 3.0 1 1 2 3 3 3 2 Coatomer WD associated region YlqD PF11068.3 CBK23037.2 - 7.4 6.6 12.9 2.9 7.9 6.8 1.7 2 0 0 2 2 2 0 YlqD protein DNA_pol_B PF00136.16 CBK23038.2 - 5.6e-134 447.4 1.3 8.1e-134 446.9 0.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBK23038.2 - 1e-56 192.1 0.1 1.7e-56 191.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBK23038.2 - 7.6e-17 61.0 13.9 1.7e-16 59.9 9.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 CBK23038.2 - 0.00025 20.8 0.4 0.0027 17.5 0.3 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 CBK23038.2 - 0.009 14.7 3.6 0.017 13.7 1.1 2.3 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral 2-oxoacid_dh PF00198.18 CBK23039.2 - 7.3e-71 238.0 0.2 9.6e-71 237.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBK23039.2 - 5.7e-17 61.1 0.3 1.4e-16 59.8 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CBK23039.2 - 7.8e-10 38.2 0.1 1.8e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CBK23039.2 - 6.9e-08 32.0 0.1 2.4e-06 27.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CBK23039.2 - 0.0012 18.2 0.9 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CBK23039.2 - 0.0027 18.0 0.3 0.037 14.3 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK23039.2 - 0.0046 16.1 0.0 0.0087 15.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein PYNP_C PF07831.8 CBK23039.2 - 0.11 11.9 0.0 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain PAT1 PF09770.4 CBK23039.2 - 1.3 7.2 11.3 1.6 6.8 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CBK23039.2 - 2.3 8.0 5.8 3 7.6 4.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 CBK23040.2 - 4.2e-49 162.7 19.8 3.4e-10 39.4 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBK23040.2 - 0.014 14.2 0.1 0.73 8.5 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like Mito_carr PF00153.22 CBK23041.2 - 1.5e-21 75.9 0.0 3e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_L10 PF00466.15 CBK23042.2 - 3.8e-22 78.0 0.4 9.4e-22 76.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CBK23042.2 - 1.6e-13 50.8 8.8 3.5e-13 49.7 5.9 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Med30 PF11315.3 CBK23042.2 - 0.087 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 30 TnpB_IS66 PF05717.8 CBK23043.2 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 IS66 Orf2 like protein DIE2_ALG10 PF04922.7 CBK23044.2 - 1.7e-57 195.2 32.9 2.9e-57 194.4 22.8 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family ABC_tran PF00005.22 CBK23044.2 - 2.1e-30 105.8 0.0 3.8e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK23044.2 - 1.1e-07 32.0 9.6 0.00035 20.6 0.0 3.8 3 1 0 4 4 4 2 AAA domain SMC_N PF02463.14 CBK23044.2 - 0.0001 21.6 1.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBK23044.2 - 0.00091 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK23044.2 - 0.0022 17.4 0.1 0.0049 16.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 CBK23044.2 - 0.0039 16.7 0.0 0.028 14.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK23044.2 - 0.0062 16.5 0.7 0.016 15.1 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 CBK23044.2 - 0.031 14.1 0.2 0.22 11.4 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 CBK23044.2 - 0.053 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CBK23044.2 - 0.086 13.3 0.1 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 CBK23044.2 - 0.097 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBK23044.2 - 0.098 12.5 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBK23044.2 - 0.11 12.8 0.1 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBK23044.2 - 0.15 11.4 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CBK23044.2 - 0.22 12.3 0.3 0.52 11.1 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBK23044.2 - 0.22 11.6 1.1 0.96 9.5 0.8 2.0 1 1 0 1 1 1 0 AAA domain Nucleoporin_FG PF13634.1 CBK23045.2 - 9.1e-31 106.4 157.6 5.9e-13 49.0 39.6 4.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region PI3_PI4_kinase PF00454.22 CBK23046.2 - 1.4e-43 149.1 1.4 3.1e-29 102.1 0.1 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.16 CBK23046.2 - 0.00016 21.4 4.0 0.00037 20.3 2.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF4135 PF13575.1 CBK23046.2 - 0.0012 17.8 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) tRNA-Thr_ED PF08915.6 CBK23046.2 - 0.026 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Met_gamma_lyase PF06838.6 CBK23046.2 - 0.096 10.9 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase FYVE_2 PF02318.11 CBK23046.2 - 0.72 9.7 9.2 0.61 10.0 4.8 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger PI3Ka PF00613.15 CBK23047.2 - 6.1e-21 74.4 0.0 9.6e-21 73.7 0.0 1.3 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Rpn3_C PF08375.6 CBK23047.2 - 0.15 12.5 0.9 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Trypan_PARP PF05887.6 CBK23047.2 - 2.3 8.0 22.4 7 6.4 15.6 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) COPI_assoc PF08507.5 CBK23048.2 - 3e-12 46.4 8.9 4.2e-12 45.9 6.2 1.2 1 0 0 1 1 1 1 COPI associated protein DUF2207 PF09972.4 CBK23048.2 - 4.1 5.8 6.4 10 4.5 3.4 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF563 PF04577.9 CBK23049.2 - 2.3e-22 79.9 1.5 3.1e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) RRM_1 PF00076.17 CBK23052.2 - 2.7e-05 23.7 0.0 0.00011 21.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23052.2 - 0.00015 21.5 0.1 0.00035 20.3 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23052.2 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SLBP_RNA_bind PF15247.1 CBK23052.2 - 0.41 10.4 4.3 0.34 10.7 1.2 2.2 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Peptidase_S8 PF00082.17 CBK23053.2 - 3.6e-27 95.2 0.2 8.2e-27 94.0 0.0 1.6 2 0 0 2 2 2 1 Subtilase family NIF PF03031.13 CBK23054.2 - 9.8e-40 135.8 0.3 1.1e-39 135.6 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_11 PF13414.1 CBK23055.2 - 2.4e-36 123.2 26.2 4.9e-12 45.3 0.3 7.4 5 2 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 CBK23055.2 - 1.4e-26 90.1 25.2 0.00016 21.3 0.0 11.1 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23055.2 - 1.6e-26 90.7 19.5 8e-05 22.0 0.0 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23055.2 - 3.1e-20 71.9 20.5 0.0024 17.7 2.2 7.7 3 1 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23055.2 - 1.3e-19 70.3 20.0 7.4e-07 29.6 0.0 7.5 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23055.2 - 5e-17 60.3 20.5 0.0039 16.8 0.1 9.9 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBK23055.2 - 3.4e-16 58.0 6.8 0.0022 18.0 0.1 8.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23055.2 - 5.6e-15 55.4 12.3 0.0013 19.0 0.1 6.6 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23055.2 - 2e-13 49.6 18.8 0.0083 16.6 0.0 9.8 3 2 8 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK23055.2 - 3.9e-12 45.8 11.6 5.6e-05 22.9 0.3 6.6 4 2 3 7 7 7 3 Tetratricopeptide repeat NARP1 PF12569.3 CBK23055.2 - 4.6e-12 45.4 7.7 0.0068 15.2 0.4 5.6 3 3 4 7 7 7 4 NMDA receptor-regulated protein 1 Apc3 PF12895.2 CBK23055.2 - 1e-11 44.7 11.9 1.4e-05 25.1 0.2 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBK23055.2 - 1.8e-07 31.1 34.2 0.011 16.1 0.0 11.0 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_5 PF12688.2 CBK23055.2 - 1.1e-06 28.7 5.0 0.015 15.3 0.1 3.3 4 0 0 4 4 4 2 Tetratrico peptide repeat TPR_7 PF13176.1 CBK23055.2 - 3.5e-05 23.2 16.9 0.0023 17.5 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat Suf PF05843.9 CBK23055.2 - 0.0015 18.2 2.1 0.31 10.7 0.1 2.5 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) MIT PF04212.13 CBK23055.2 - 0.012 15.4 10.6 0.45 10.4 0.5 4.0 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 CBK23055.2 - 0.02 13.6 1.0 3.3 6.3 0.0 3.4 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 CBK23055.2 - 0.029 14.7 0.3 38 5.1 0.0 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Clathrin PF00637.15 CBK23055.2 - 0.075 12.6 1.3 6.9 6.2 0.0 2.8 2 0 0 2 2 2 0 Region in Clathrin and VPS Vps5 PF09325.5 CBK23055.2 - 0.47 9.6 9.4 0.21 10.8 0.8 3.3 4 0 0 4 4 4 0 Vps5 C terminal like TPR_10 PF13374.1 CBK23055.2 - 0.9 9.5 0.0 0.9 9.5 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat PRKCSH_1 PF13015.1 CBK23056.2 - 7e-05 22.3 0.9 0.00076 18.9 0.6 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CBK23056.2 - 0.00016 22.4 1.5 0.00016 22.4 1.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein EF_TS PF00889.14 CBK23059.2 - 3.3e-58 196.6 1.0 4.4e-58 196.2 0.7 1.2 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.26 CBK23059.2 - 1.3e-08 34.3 0.4 5.3e-08 32.4 0.3 2.1 1 1 0 1 1 1 1 UBA/TS-N domain DUF4332 PF14229.1 CBK23059.2 - 0.029 14.3 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) U-box PF04564.10 CBK23060.2 - 7e-23 80.3 1.8 9.7e-23 79.9 1.2 1.2 1 0 0 1 1 1 1 U-box domain DUF1076 PF06416.7 CBK23060.2 - 0.095 12.4 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1076) SF3b10 PF07189.6 CBK23061.2 - 6.7e-24 83.5 0.0 7.4e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) HVSL PF09749.4 CBK23063.2 - 2.6e-38 131.4 0.6 3e-38 131.1 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 CBK23063.2 - 0.0059 16.3 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ribosomal_S27e PF01667.12 CBK23064.2 - 2.6e-21 74.9 5.3 2.7e-21 74.8 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 CBK23064.2 - 0.0052 16.0 2.8 0.0068 15.6 1.9 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 CBK23064.2 - 0.011 15.5 2.7 0.012 15.5 1.9 1.2 1 0 0 1 1 1 0 IBR domain zf-NADH-PPase PF09297.6 CBK23064.2 - 0.012 15.1 1.3 0.035 13.5 0.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.1 CBK23064.2 - 0.017 14.8 1.4 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK23064.2 - 0.029 13.9 1.4 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CBK23064.2 - 0.22 10.7 4.7 0.27 10.4 2.2 1.9 1 1 1 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 CBK23064.2 - 0.25 11.1 1.8 0.28 10.9 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF164 PF02591.10 CBK23064.2 - 0.28 11.0 2.1 1.2 9.0 1.5 2.0 1 1 0 1 1 1 0 Putative zinc ribbon domain DUF3133 PF11331.3 CBK23064.2 - 0.31 10.6 0.2 0.31 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-LSD1 PF06943.7 CBK23064.2 - 0.34 10.5 2.5 8.3 6.1 0.5 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Mu-like_Com PF10122.4 CBK23064.2 - 0.36 9.9 4.5 2.3 7.3 0.1 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com Sgf11 PF08209.6 CBK23064.2 - 1 8.7 3.7 3.8 6.9 0.4 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 CBK23064.2 - 1 9.2 4.4 2.4 8.0 3.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.19 CBK23064.2 - 1.1 9.1 4.7 3.5 7.6 3.3 1.7 1 1 0 1 1 1 0 B-box zinc finger Prok-RING_1 PF14446.1 CBK23064.2 - 1.3 8.7 5.1 1.9 8.3 3.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 CBK23064.2 - 2.9 7.6 5.1 26 4.5 2.5 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) zf-C4_Topoisom PF01396.14 CBK23064.2 - 5.9 6.4 6.0 4.9 6.7 0.6 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Tfb2 PF03849.9 CBK23066.2 - 6.6e-30 103.9 0.0 1e-29 103.3 0.0 1.2 1 1 0 1 1 1 1 Transcription factor Tfb2 DUF3226 PF11536.3 CBK23067.2 - 0.02 14.3 0.0 0.02 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Arm PF00514.18 CBK23068.2 - 5.1e-08 32.4 4.1 7.7e-05 22.3 0.1 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBK23068.2 - 0.13 12.5 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats Chordopox_A13L PF05961.6 CBK23069.2 - 0.072 13.0 0.1 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein APC10 PF03256.11 CBK23071.2 - 1.5e-32 112.7 0.1 1.7e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CBK23071.2 - 3.8e-09 36.4 0.1 4.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain ubiquitin PF00240.18 CBK23072.2 - 9.3e-08 31.3 0.1 1.3e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK23072.2 - 0.00015 21.4 0.1 0.00036 20.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cob_adeno_trans PF01923.13 CBK23073.2 - 2e-48 164.2 0.0 3e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase SNARE PF05739.14 CBK23075.2 - 8e-08 31.8 1.7 8e-08 31.8 1.2 3.4 5 0 0 5 5 5 1 SNARE domain DUF745 PF05335.8 CBK23075.2 - 0.23 10.9 7.6 0.075 12.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3858 PF12970.2 CBK23075.2 - 0.55 10.0 3.1 0.43 10.3 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) NPV_P10 PF05531.7 CBK23075.2 - 1.1 9.5 8.5 1.3 9.3 0.6 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 CBK23075.2 - 6.5 6.7 8.1 0.22 11.4 0.4 2.1 2 1 0 2 2 2 0 FlxA-like protein Syntaxin-6_N PF09177.6 CBK23075.2 - 8.2 6.9 9.5 16 5.9 1.3 3.1 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Phage_GPO PF05929.6 CBK23075.2 - 8.5 5.5 8.3 3 7.0 1.4 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PPTA PF01239.17 CBK23076.2 - 3.8e-28 95.6 8.7 2.8e-07 29.6 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 CBK23077.2 - 0.059 13.1 0.2 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23077.2 - 0.077 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBK23078.2 - 9.8e-30 102.3 0.0 1.3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBK23078.2 - 7.3e-06 26.1 0.0 3.4e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK23078.2 - 5.5e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.8 CBK23078.2 - 6e-05 22.9 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.1 CBK23078.2 - 0.00055 20.0 0.0 0.0026 17.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CBK23078.2 - 0.0021 17.8 0.0 0.088 12.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBK23078.2 - 0.043 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family SGS PF05002.10 CBK23079.2 - 1.9e-08 33.9 0.0 3.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CBK23079.2 - 4e-08 33.6 0.3 8.3e-08 32.6 0.2 1.6 1 1 0 1 1 1 1 CS domain IF-2B PF01008.12 CBK23080.2 - 4e-69 232.7 0.0 4.7e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.20 CBK23081.2 - 4.1e-12 46.3 0.0 5.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBK23081.2 - 4.2e-05 23.2 0.0 0.00043 19.9 0.0 2.0 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CBK23081.2 - 0.063 12.9 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nop PF01798.13 CBK23082.2 - 2.5e-61 205.3 0.9 9.3e-61 203.5 0.6 2.0 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBK23082.2 - 1.2e-26 92.2 0.4 2.3e-26 91.3 0.3 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBK23082.2 - 3.5e-20 71.9 0.5 3.5e-20 71.9 0.3 3.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain SprA-related PF12118.3 CBK23082.2 - 0.34 10.2 34.7 0.57 9.4 24.0 1.4 1 0 0 1 1 1 0 SprA-related family CDC27 PF09507.5 CBK23082.2 - 1.1 8.4 60.6 1.4 8.0 42.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_S17e PF00833.13 CBK23083.2 - 2.4e-53 179.0 1.4 2.8e-53 178.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 TruD PF01142.13 CBK23084.2 - 2.5e-44 151.4 0.0 5.9e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Ribosomal_L22 PF00237.14 CBK23085.2 - 1e-16 60.7 0.1 1.9e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LIM PF00412.17 CBK23086.2 - 2.4e-25 88.3 24.6 2.1e-14 53.2 5.7 2.5 2 0 0 2 2 2 2 LIM domain CH PF00307.26 CBK23086.2 - 7.4e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DZR PF12773.2 CBK23086.2 - 0.12 12.2 24.3 2.3 8.0 1.6 4.9 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBK23086.2 - 0.2 11.6 23.2 9.8 6.2 3.4 4.7 4 1 0 4 4 4 0 Zinc ribbon domain PSCyt3 PF07627.6 CBK23086.2 - 0.72 9.7 3.7 15 5.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1588) zf-C2HC5 PF06221.8 CBK23086.2 - 1.5 8.6 24.7 0.14 11.9 3.3 4.8 3 2 2 5 5 5 0 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 CBK23086.2 - 1.7 7.9 16.3 1.2 8.5 0.3 4.5 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 CBK23086.2 - 6.9 6.3 22.9 2.6 7.6 0.6 4.9 4 2 0 4 4 4 0 zinc-ribbon domain Calsarcin PF05556.6 CBK23087.2 - 0.006 15.8 0.3 0.0094 15.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) DUF676 PF05057.9 CBK23088.2 - 2.8e-22 79.1 0.1 5.5e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CBK23088.2 - 0.05 13.1 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Lipase PF00151.14 CBK23088.2 - 0.094 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase Abhydrolase_8 PF06259.7 CBK23088.2 - 0.094 12.2 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DNA_pol3_delta2 PF13177.1 CBK23089.2 - 1.4e-15 57.3 0.0 7.4e-13 48.4 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 CBK23089.2 - 2.2e-15 57.0 0.0 4.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBK23089.2 - 8.4e-12 44.9 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CBK23089.2 - 1.7e-10 40.2 0.0 1.8e-05 23.6 0.0 2.5 1 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBK23089.2 - 3.1e-07 30.5 0.3 9.8e-05 22.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBK23089.2 - 3.4e-07 29.5 0.0 8.4e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBK23089.2 - 6.6e-07 29.2 0.0 3.5e-06 26.9 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.1 CBK23089.2 - 2.7e-05 23.8 0.0 8.1e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK23089.2 - 3e-05 23.6 0.0 7.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBK23089.2 - 5.4e-05 23.2 0.0 0.00026 21.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CBK23089.2 - 8.2e-05 21.6 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CBK23089.2 - 0.00034 21.4 0.0 0.00081 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK23089.2 - 0.00085 19.0 0.2 0.0029 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK23089.2 - 0.00093 19.5 0.0 0.0022 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CBK23089.2 - 0.0012 18.3 0.2 0.064 12.7 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.1 CBK23089.2 - 0.0012 18.4 0.5 0.019 14.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK23089.2 - 0.0026 18.0 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBK23089.2 - 0.0028 16.8 0.1 0.028 13.5 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CBK23089.2 - 0.0029 17.2 0.2 0.006 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBK23089.2 - 0.0052 16.2 0.3 0.83 9.0 0.1 2.4 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 CBK23089.2 - 0.0055 16.2 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit PhoH PF02562.11 CBK23089.2 - 0.0088 15.2 0.0 4 6.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 CBK23089.2 - 0.0096 15.7 0.1 0.018 14.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBK23089.2 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBK23089.2 - 0.011 15.1 0.3 0.12 11.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.6 CBK23089.2 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBK23089.2 - 0.017 15.3 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 CBK23089.2 - 0.019 13.8 0.0 0.052 12.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 CBK23089.2 - 0.019 14.7 0.0 0.046 13.5 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 CBK23089.2 - 0.021 14.2 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 CBK23089.2 - 0.028 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SNF2_N PF00176.18 CBK23089.2 - 0.032 13.0 0.0 0.3 9.8 0.0 2.0 2 0 0 2 2 2 0 SNF2 family N-terminal domain MobB PF03205.9 CBK23089.2 - 0.033 13.8 0.1 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CBK23089.2 - 0.042 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK23089.2 - 0.057 12.8 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CBK23089.2 - 0.066 12.6 0.1 0.16 11.3 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 CBK23089.2 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CBK23089.2 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter MCM PF00493.18 CBK23090.2 - 1.9e-133 444.3 0.8 2.9e-133 443.7 0.5 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBK23090.2 - 5.9e-15 55.8 0.1 1.8e-14 54.2 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBK23090.2 - 1.1e-05 24.7 0.0 0.00011 21.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBK23090.2 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBK23090.2 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBK23090.2 - 0.03 13.7 0.0 0.066 12.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain LSM PF01423.17 CBK23091.2 - 2.2e-19 68.7 0.0 2.5e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 CBK23092.2 - 2.1e-40 137.9 0.0 4.1e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23092.2 - 3e-20 71.8 0.0 7.2e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBK23092.2 - 3.7e-11 42.3 0.0 7.3e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBK23092.2 - 0.06 13.1 1.5 2.9 7.6 0.0 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit efThoc1 PF11957.3 CBK23094.2 - 5.8e-29 100.9 2.4 5.2e-28 97.7 1.6 2.3 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 CBK23096.2 - 5.4e-59 198.7 0.0 6.6e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CBK23096.2 - 1.3e-06 28.3 0.0 3.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK23096.2 - 3.9e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK23096.2 - 4.1e-05 23.6 0.0 8.1e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBK23096.2 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBK23096.2 - 0.00012 22.2 0.0 0.0005 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBK23096.2 - 0.00052 19.7 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 CBK23096.2 - 0.00067 19.7 0.0 0.0019 18.3 0.0 1.9 2 1 0 2 2 1 1 RNA helicase AAA_17 PF13207.1 CBK23096.2 - 0.00069 20.4 0.0 0.003 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 CBK23096.2 - 0.00072 20.0 0.0 0.002 18.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_5 PF07728.9 CBK23096.2 - 0.0025 17.5 0.2 0.017 14.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CBK23096.2 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 CBK23096.2 - 0.019 15.1 0.0 0.045 13.9 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CBK23096.2 - 0.036 14.3 0.1 0.061 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 CBK23096.2 - 0.037 13.7 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBK23096.2 - 0.041 13.7 0.0 0.075 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBK23096.2 - 0.055 12.8 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 CBK23096.2 - 0.065 12.3 0.0 0.72 8.9 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.1 CBK23096.2 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fimbrillin_C PF15495.1 CBK23096.2 - 0.085 13.0 0.7 0.14 12.3 0.1 1.6 2 0 0 2 2 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal PhnA PF03831.9 CBK23096.2 - 0.09 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 PhnA protein Ras PF00071.17 CBK23096.2 - 0.098 12.0 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 CBK23096.2 - 0.1 12.1 0.1 1.8 8.0 0.0 2.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 CBK23096.2 - 0.12 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pkinase PF00069.20 CBK23097.2 - 1.5e-56 191.4 0.0 2.3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23097.2 - 5.8e-26 91.1 0.0 9.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CBK23097.2 - 4.4e-14 52.3 5.2 9.6e-08 32.0 0.3 3.0 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CBK23097.2 - 2.9e-13 48.0 7.3 5e-06 25.4 1.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBK23097.2 - 1.6e-12 46.1 6.1 1.5e-05 24.4 0.3 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBK23097.2 - 2.4e-07 30.2 6.1 3.5e-05 23.3 2.7 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK23097.2 - 1.2e-05 24.4 3.7 0.011 15.0 0.8 3.9 3 0 0 3 3 3 1 EF hand Kdo PF06293.9 CBK23097.2 - 0.0012 17.9 0.0 0.0036 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK23097.2 - 0.011 15.4 0.0 0.09 12.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 CBK23097.2 - 0.016 14.3 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 CBK23097.2 - 0.017 14.7 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.20 CBK23098.2 - 9.4e-59 198.6 0.0 1.6e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23098.2 - 1.2e-29 103.1 0.0 2.8e-28 98.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK23098.2 - 2.5e-05 24.1 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBK23098.2 - 0.0024 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 CBK23098.2 - 0.021 14.3 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CBK23098.2 - 0.035 13.0 0.0 0.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 CBK23098.2 - 0.046 13.0 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family ATS3 PF06232.6 CBK23098.2 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) zf-Di19 PF05605.7 CBK23099.2 - 0.009 16.1 20.1 0.72 10.0 0.1 4.4 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding PEPCK_ATP PF01293.15 CBK23100.2 - 8e-05 21.3 0.0 0.0001 20.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DNA_pol_A PF00476.15 CBK23101.2 - 5.1e-70 236.0 0.0 6.1e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A nsp7 PF08716.5 CBK23101.2 - 0.91 9.9 5.3 1.3 9.4 1.9 2.6 2 1 0 2 2 2 0 nsp7 replicase PHD_2 PF13831.1 CBK23102.2 - 0.021 14.1 15.1 0.021 14.1 10.4 2.7 3 0 0 3 3 3 0 PHD-finger zf-CCCH_2 PF14608.1 CBK23103.2 - 0.042 13.8 7.8 0.13 12.3 5.4 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Macoilin PF09726.4 CBK23103.2 - 4.2 5.5 13.3 5.4 5.1 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein CPSF_A PF03178.10 CBK23104.2 - 2.5e-11 43.2 0.0 3.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region DUF2713 PF10897.3 CBK23104.2 - 0.037 13.2 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Prok-RING_2 PF14445.1 CBK23105.2 - 0.041 13.8 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Xpo1 PF08389.7 CBK23106.2 - 1.2e-12 48.0 9.2 1.2e-11 44.6 2.3 2.9 3 0 0 3 3 3 2 Exportin 1-like protein HEAT_2 PF13646.1 CBK23106.2 - 0.0077 16.4 0.1 0.37 11.0 0.0 3.2 2 1 0 3 3 3 1 HEAT repeats Arm PF00514.18 CBK23106.2 - 0.021 14.6 0.3 8.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 CBK23106.2 - 0.024 14.5 3.1 0.028 14.3 0.1 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain UTP15_C PF09384.5 CBK23106.2 - 0.053 13.2 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 UTP15 C terminal Mito_carr PF00153.22 CBK23107.2 - 1.3e-78 258.7 3.7 2.8e-26 91.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAP PF03866.8 CBK23107.2 - 0.057 13.2 0.3 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) UCR_Fe-S_N PF10399.4 CBK23107.2 - 0.41 9.8 4.4 0.1 11.7 0.7 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal EF-hand_6 PF13405.1 CBK23108.2 - 1.4e-08 33.9 1.7 0.097 12.6 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CBK23108.2 - 2.1e-08 32.8 0.2 0.015 14.5 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBK23108.2 - 2e-05 24.6 4.5 0.14 12.3 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBK23108.2 - 9.7e-05 21.5 0.3 0.046 13.0 0.0 3.7 4 0 0 4 4 4 1 EF hand DUF2934 PF11154.3 CBK23108.2 - 0.0052 16.1 0.1 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) EF-hand_8 PF13833.1 CBK23108.2 - 0.01 15.4 0.1 0.24 11.0 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain pair DEAD PF00270.24 CBK23110.2 - 7.7e-10 38.5 0.2 8e-09 35.2 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase PA28_beta PF02252.13 CBK23110.2 - 0.034 13.6 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit Myb_DNA-binding PF00249.26 CBK23111.2 - 2.1e-20 72.5 7.0 4.4e-11 42.6 0.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK23111.2 - 1.1e-19 70.3 8.5 5.2e-13 48.8 1.9 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 CBK23111.2 - 3.8e-14 52.4 10.0 3.8e-14 52.4 7.0 3.8 4 1 1 5 5 5 1 pre-mRNA splicing factor component DUF325 PF03804.8 CBK23111.2 - 0.024 14.3 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 Viral domain of unknown function GTP_EFTU PF00009.22 CBK23112.2 - 3e-62 209.4 0.0 5.1e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBK23112.2 - 1.2e-33 115.2 0.0 2.8e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBK23112.2 - 1.1e-19 70.0 0.0 2.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBK23112.2 - 5.2e-15 55.0 0.0 1.5e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBK23112.2 - 7.4e-13 48.4 0.1 2.3e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK23112.2 - 9.8e-05 22.2 0.0 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2703 PF10865.3 CBK23112.2 - 0.12 12.3 0.1 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Carboxyl_trans PF01039.17 CBK23113.2 - 6.8e-191 634.8 0.1 8.1e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK23113.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Rep_fac_C PF08542.6 CBK23114.2 - 4.3e-14 52.2 0.5 2.3e-13 49.8 0.0 2.5 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBK23114.2 - 2.8e-13 49.8 0.3 5.4e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBK23114.2 - 5.9e-08 32.9 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBK23114.2 - 0.00087 18.0 0.1 0.0014 17.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 CBK23114.2 - 0.0019 18.2 0.1 0.014 15.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 CBK23114.2 - 0.0045 17.1 0.2 0.031 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK23114.2 - 0.0076 16.2 0.1 0.099 12.6 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CBK23114.2 - 0.0083 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBK23114.2 - 0.013 15.3 0.0 0.068 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK23114.2 - 0.015 14.7 0.0 0.073 12.5 0.0 1.9 1 1 2 3 3 3 0 AAA-like domain Bac_DnaA PF00308.13 CBK23114.2 - 0.016 14.8 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein DNA_pol3_delta PF06144.8 CBK23114.2 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 CBK23114.2 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain UPF0126 PF03458.8 CBK23115.2 - 3.6e-05 23.3 1.1 3.6e-05 23.3 0.7 2.6 3 0 0 3 3 3 1 UPF0126 domain LRR_8 PF13855.1 CBK23116.2 - 0.34 10.7 2.3 0.79 9.5 0.3 2.5 2 1 0 2 2 2 0 Leucine rich repeat CPSase_L_D2 PF02786.12 CBK23117.2 - 2.7e-72 242.4 0.0 4.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK23117.2 - 6.2e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK23117.2 - 7.8e-35 119.1 0.0 1.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK23117.2 - 2.8e-18 65.3 0.2 5.9e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK23117.2 - 1.8e-09 36.7 0.0 4.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK23117.2 - 3.8e-08 32.8 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK23117.2 - 4.5e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK23117.2 - 7.7e-08 31.9 0.1 3.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK23117.2 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK23117.2 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK23117.2 - 0.0024 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK23117.2 - 0.0037 16.9 0.4 0.012 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK23117.2 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK23117.2 - 0.015 15.6 0.0 0.46 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK23117.2 - 0.041 13.9 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK23117.2 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK23117.2 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK23117.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain HrpB7 PF09486.5 CBK23118.2 - 0.019 14.8 9.0 0.15 11.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.1 CBK23118.2 - 0.043 13.0 14.7 0.046 12.9 9.1 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AARP2CN PF08142.7 CBK23118.2 - 0.055 13.0 0.5 0.092 12.2 0.4 1.4 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Bap31 PF05529.7 CBK23118.2 - 0.41 10.0 12.1 0.59 9.5 6.0 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 CBK23118.2 - 1.5 8.7 12.8 3.6 7.5 8.9 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.7 CBK23118.2 - 1.9 6.7 5.1 2.2 6.5 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 CBK23118.2 - 2.2 8.6 10.3 6.3 7.1 5.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 CBK23118.2 - 5.1 6.0 15.8 4 6.4 10.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Flagellin_N PF00669.15 CBK23118.2 - 6.5 6.5 9.8 0.3 10.8 1.7 2.2 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region FAM150 PF15129.1 CBK23118.2 - 9.5 6.1 6.7 28 4.5 2.7 2.3 2 1 0 2 2 2 0 FAM150 family Ras PF00071.17 CBK23119.2 - 8.6e-61 204.0 0.2 1e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK23119.2 - 3.6e-19 69.4 0.1 9.4e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK23119.2 - 2.1e-12 46.6 0.1 2.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBK23119.2 - 2.1e-05 24.4 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK23119.2 - 7.1e-05 22.0 0.0 9.2e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBK23119.2 - 0.00015 21.2 0.0 0.00072 19.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBK23119.2 - 0.066 13.3 0.1 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBK23119.2 - 0.07 13.0 0.1 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBK23119.2 - 0.08 12.1 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L30 PF00327.15 CBK23121.2 - 1.7e-19 69.0 0.2 3.7e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBK23121.2 - 9.8e-10 38.3 12.1 1.8e-09 37.4 8.4 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DBINO PF13892.1 CBK23121.2 - 0.064 13.3 5.5 0.12 12.4 3.8 1.4 1 0 0 1 1 1 0 DNA-binding domain Guanylate_cyc PF00211.15 CBK23121.2 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain AlaDh_PNT_C PF01262.16 CBK23121.2 - 0.11 12.0 0.6 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pro_isomerase PF00160.16 CBK23122.2 - 1e-45 155.7 0.0 1.2e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glycos_transf_2 PF00535.21 CBK23123.2 - 1.6e-24 86.4 0.0 2.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBK23123.2 - 6.9e-13 48.3 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CBK23123.2 - 5.6e-07 29.5 0.0 8.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CBK23123.2 - 0.0019 18.4 0.0 0.022 15.0 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CBK23123.2 - 0.0038 16.6 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CAP59_mtransfer PF11735.3 CBK23123.2 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Anp1 PF03452.9 CBK23123.2 - 0.089 11.9 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 Anp1 PolyG_pol PF01518.11 CBK23124.2 - 0.014 13.9 0.0 0.026 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma NS protein UQ_con PF00179.21 CBK23125.2 - 1.9e-39 134.3 0.0 2.8e-39 133.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBK23125.2 - 0.0024 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBK23125.2 - 0.047 13.5 0.1 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 RWD domain DUF367 PF04034.8 CBK23127.2 - 3.9e-48 162.2 0.0 5.1e-48 161.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CBK23127.2 - 3.1e-12 45.8 0.1 6e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI A_deamin PF02137.13 CBK23128.2 - 1.3e-71 241.7 0.3 1.7e-71 241.3 0.2 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain UPF0158 PF03682.8 CBK23128.2 - 0.086 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Fer2 PF00111.22 CBK23129.2 - 2.8e-13 49.4 2.7 4.2e-13 48.8 1.9 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Aa_trans PF01490.13 CBK23130.2 - 5.6e-26 90.9 22.5 6.7e-26 90.6 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2427 PF10348.4 CBK23130.2 - 0.74 9.4 10.8 0.12 11.9 3.4 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2427) Cytochrom_B_C PF00032.12 CBK23130.2 - 5.5 7.2 12.0 5.3 7.3 2.6 2.5 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD H_PPase PF03030.11 CBK23132.2 - 7.2e-258 857.3 26.2 8.3e-258 857.1 18.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Ribosomal_L2_C PF03947.13 CBK23133.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK23133.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Phosphorylase PF00343.15 CBK23134.2 - 9.1e-276 916.3 0.1 1.1e-275 916.0 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GTP_EFTU PF00009.22 CBK23136.2 - 2.5e-38 131.4 0.0 3.6e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBK23136.2 - 1.3e-22 79.5 0.0 2.7e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBK23136.2 - 1.5e-17 63.2 0.0 3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBK23136.2 - 1.7e-08 34.4 0.0 4.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CBK23136.2 - 1.5e-07 31.1 0.0 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CBK23136.2 - 0.00074 20.0 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein TGT PF01702.13 CBK23137.2 - 3.7e-51 173.6 0.3 4.6e-51 173.3 0.2 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF832 PF05734.6 CBK23137.2 - 0.019 14.1 0.2 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Mak10 PF04112.8 CBK23138.2 - 4.2e-11 42.3 0.4 7.2e-11 41.5 0.3 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Dynein_heavy PF03028.10 CBK23139.2 - 4.3e-136 454.7 0.0 4.3e-136 454.7 0.0 2.2 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBK23139.2 - 4.8e-123 410.6 16.8 4.8e-123 410.6 11.6 5.0 5 2 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBK23139.2 - 7.7e-108 361.3 16.5 7.7e-108 361.3 11.4 4.7 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBK23139.2 - 1.2e-85 286.7 0.0 4.2e-85 284.9 0.0 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CBK23139.2 - 3.6e-43 147.0 0.1 9.3e-43 145.6 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBK23139.2 - 1.1e-41 142.5 0.3 1.1e-40 139.3 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 CBK23139.2 - 2.7e-35 121.1 0.0 2.2e-15 56.5 0.0 7.4 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) MT PF12777.2 CBK23139.2 - 3.8e-26 91.6 6.8 8.8e-26 90.4 4.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBK23139.2 - 6.1e-24 84.5 1.0 6.7e-22 77.8 0.0 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region D3 AAA PF00004.24 CBK23139.2 - 2e-17 63.6 0.0 0.00013 22.1 0.0 5.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBK23139.2 - 5e-16 59.2 2.7 0.00026 21.0 0.0 6.8 6 0 0 6 6 4 3 AAA ATPase domain AAA_22 PF13401.1 CBK23139.2 - 9.3e-16 58.1 2.6 0.00038 20.5 0.0 7.5 8 0 0 8 8 5 3 AAA domain AAA_33 PF13671.1 CBK23139.2 - 8.8e-10 38.6 0.1 0.012 15.4 0.0 5.8 6 0 0 6 6 4 2 AAA domain AAA_17 PF13207.1 CBK23139.2 - 1.9e-08 35.1 0.0 1.6 9.5 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 CBK23139.2 - 3.8e-08 33.2 0.0 0.32 10.8 0.0 5.9 5 0 0 5 5 5 2 AAA domain Zeta_toxin PF06414.7 CBK23139.2 - 9.7e-08 31.3 0.0 0.017 14.1 0.0 4.5 5 0 0 5 5 5 2 Zeta toxin AAA_18 PF13238.1 CBK23139.2 - 2.8e-07 30.8 0.0 0.62 10.3 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBK23139.2 - 1.6e-06 27.7 0.0 0.58 9.9 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_29 PF13555.1 CBK23139.2 - 2.5e-06 26.9 0.0 0.063 12.8 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CBK23139.2 - 6.9e-06 25.3 0.1 1.7 7.7 0.0 4.7 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 CBK23139.2 - 1.9e-05 24.2 0.0 1.4 8.3 0.0 4.9 5 0 0 5 5 5 1 FtsK/SpoIIIE family DUF258 PF03193.11 CBK23139.2 - 4.8e-05 22.6 0.0 0.36 10.0 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBK23139.2 - 0.00011 21.8 11.1 0.094 12.1 0.0 6.8 6 1 0 6 6 6 1 AAA-like domain RNA_helicase PF00910.17 CBK23139.2 - 0.00038 20.6 0.0 6.1 7.0 0.0 5.0 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 CBK23139.2 - 0.0011 18.4 0.0 2.3 7.5 0.0 4.0 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 CBK23139.2 - 0.0042 16.7 2.0 5.8 6.5 0.0 4.3 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CBK23139.2 - 0.0078 15.6 1.0 1.9 7.9 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBK23139.2 - 0.0088 16.3 0.0 0.0088 16.3 0.0 5.8 7 0 0 7 7 4 1 ABC transporter MobB PF03205.9 CBK23139.2 - 0.043 13.5 0.7 4.9 6.8 0.0 3.7 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBK23139.2 - 0.26 11.2 0.1 2.8 7.9 0.0 3.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 CBK23139.2 - 1.7 7.8 1.2 7.7 5.6 0.0 2.7 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain SRP9-21 PF05486.7 CBK23142.2 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Peptidase_M16 PF00675.15 CBK23142.2 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) HSP70 PF00012.15 CBK23143.2 - 1.5e-106 356.7 11.2 8.4e-105 350.9 7.8 3.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23143.2 - 0.01 14.4 0.0 0.022 13.3 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein Baculo_FP PF03258.9 CBK23143.2 - 0.039 13.0 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Baculovirus FP protein zf-CCCH PF00642.19 CBK23144.2 - 2.1e-06 27.2 8.8 8.8e-06 25.2 0.6 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ARF7EP_C PF14949.1 CBK23144.2 - 0.042 14.2 1.2 0.042 14.2 0.8 4.1 3 2 0 4 4 4 0 ARF7 effector protein C-terminus zf-CCCH_2 PF14608.1 CBK23144.2 - 3.4 7.8 16.5 0.55 10.3 0.9 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type SecA_DEAD PF07517.9 CBK23144.2 - 4.4 6.5 8.1 0.19 10.9 1.2 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain RNase_Zc3h12a PF11977.3 CBK23145.2 - 2.2e-09 37.3 1.0 1.4e-08 34.7 0.7 2.0 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain LSM PF01423.17 CBK23146.2 - 1.9e-06 27.3 0.1 2.3e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain HSP70 PF00012.15 CBK23147.2 - 9.9e-79 264.8 0.5 1.3e-78 264.4 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23147.2 - 4.1e-14 51.9 4.1 4.7e-10 38.5 0.5 3.1 3 0 0 3 3 3 3 MreB/Mbl protein Hydantoinase_A PF01968.13 CBK23147.2 - 1.4e-05 24.4 0.2 0.0016 17.6 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FtsA PF14450.1 CBK23147.2 - 3.4e-05 23.6 5.1 1.9 8.3 0.1 4.3 4 0 0 4 4 4 3 Cell division protein FtsA StbA PF06406.6 CBK23147.2 - 0.0012 17.8 0.3 0.0054 15.7 0.0 2.0 2 0 0 2 2 2 1 StbA protein Beach PF02138.13 CBK23148.2 - 4e-101 337.9 1.9 6.7e-101 337.2 1.3 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CBK23148.2 - 1.8e-25 88.8 1.0 5.2e-25 87.3 0.7 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 CBK23148.2 - 4.3e-16 58.0 1.3 8.2e-08 31.8 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 CBK23149.2 - 1e-09 38.8 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBK23149.2 - 0.00022 21.2 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Lipase_3 PF01764.20 CBK23150.2 - 1.2e-17 63.8 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CBK23150.2 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CBK23150.2 - 0.0099 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 CBK23150.2 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBK23150.2 - 0.02 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 CBK23150.2 - 0.046 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Adap_comp_sub PF00928.16 CBK23151.2 - 1.7e-82 276.4 0.0 2.1e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK23151.2 - 0.00013 21.7 4.0 0.00019 21.1 2.5 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 CBK23151.2 - 0.093 12.3 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain LRR_4 PF12799.2 CBK23152.2 - 6.2e-07 28.8 2.5 0.033 13.8 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBK23152.2 - 5.7e-05 22.7 1.9 0.67 10.1 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 CBK23152.2 - 6.4e-05 22.4 4.0 0.15 12.2 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CBK23152.2 - 7e-05 22.3 2.4 2.6 8.6 0.3 4.9 4 0 0 4 4 4 2 Leucine rich repeat Cep57_CLD_2 PF14197.1 CBK23152.2 - 0.00082 19.2 11.8 0.00082 19.2 8.2 8.3 6 1 2 8 8 8 3 Centrosome localisation domain of PPC89 LRR_8 PF13855.1 CBK23152.2 - 0.0031 17.2 3.7 0.42 10.4 0.1 3.8 3 1 0 3 3 3 1 Leucine rich repeat DUF1993 PF09351.5 CBK23152.2 - 2.8 7.8 20.7 0.51 10.2 0.2 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1993) Filament PF00038.16 CBK23152.2 - 2.8 7.3 101.6 0.6 9.5 22.4 4.2 1 1 1 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CBK23152.2 - 3.3 7.4 109.5 0.16 11.6 11.2 8.1 2 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 CBK23152.2 - 5.2 6.2 104.1 0.94 8.6 10.1 6.1 2 2 5 7 7 7 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.17 CBK23153.2 - 3.2e-11 42.7 0.0 5.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23153.2 - 2.1e-09 37.2 0.0 3.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 CBK23153.2 - 2.3e-07 30.3 0.0 4.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 CBK23153.2 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAGA PF09237.6 CBK23154.2 - 0.13 11.8 1.8 0.17 11.4 0.6 1.7 1 1 1 2 2 2 0 GAGA factor LRR_6 PF13516.1 CBK23155.2 - 1.7e-22 76.8 21.1 0.0015 18.4 0.1 9.0 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.2 CBK23155.2 - 1.7e-11 43.4 17.8 0.00057 19.4 0.0 6.1 6 1 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK23155.2 - 2.4e-08 33.5 21.7 0.014 15.1 0.5 7.3 3 2 3 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CBK23155.2 - 4.6e-08 32.0 22.4 0.32 11.1 0.0 8.9 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 CBK23155.2 - 8.1e-08 31.2 12.2 1.7 9.1 0.0 8.1 8 0 0 8 8 8 2 Leucine rich repeat HSP70 PF00012.15 CBK23156.2 - 1e-151 505.8 0.1 1.1e-151 505.7 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23156.2 - 5e-18 64.7 0.0 1.9e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 CBK23156.2 - 0.00083 18.2 0.1 1.3 7.7 0.0 2.7 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CBK23156.2 - 0.033 14.0 5.1 1.1 9.1 0.0 3.8 4 0 0 4 4 4 0 Cell division protein FtsA FGGY_C PF02782.11 CBK23156.2 - 0.043 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MM_CoA_mutase PF01642.17 CBK23157.2 - 1.7e-238 791.9 0.9 2.1e-238 791.6 0.7 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 CBK23157.2 - 7.7e-11 41.9 0.6 2.1e-10 40.4 0.2 1.9 2 0 0 2 2 2 1 B12 binding domain Pox_Ag35 PF03286.9 CBK23159.2 - 0.038 13.5 17.5 0.045 13.2 12.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.6 CBK23159.2 - 0.076 12.5 19.3 0.092 12.2 13.4 1.0 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 CBK23159.2 - 0.26 10.6 20.8 0.28 10.5 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CTP_transf_2 PF01467.21 CBK23159.2 - 0.29 11.1 2.1 0.38 10.7 1.5 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Paf1 PF03985.8 CBK23159.2 - 0.34 9.6 22.5 0.34 9.5 15.6 1.0 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.7 CBK23159.2 - 2 7.0 6.0 2.3 6.9 4.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.5 CBK23159.2 - 2.2 8.2 20.1 2.9 7.8 14.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 CBK23159.2 - 2.4 5.9 23.3 2.5 5.9 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family APG6 PF04111.7 CBK23159.2 - 2.6 6.9 17.0 2.7 6.9 11.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 NPR3 PF03666.8 CBK23159.2 - 2.7 6.4 14.8 2.7 6.4 10.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNase_H2-Ydr279 PF09468.5 CBK23159.2 - 4.4 6.4 12.4 5 6.2 8.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Spore_coat_CotO PF14153.1 CBK23159.2 - 6.4 6.1 22.8 8.1 5.8 15.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.1 CBK23159.2 - 7.9 6.1 12.2 9.2 5.9 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CBK23159.2 - 9.2 5.9 10.9 12 5.5 7.6 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 CBK23159.2 - 9.5 6.0 6.7 10 5.9 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region He_PIG PF05345.7 CBK23160.2 - 5.5e-14 51.9 14.5 0.00023 21.1 1.3 5.1 4 0 0 4 4 4 3 Putative Ig domain TMEM154 PF15102.1 CBK23160.2 - 0.0028 17.3 0.9 0.0085 15.7 0.6 1.8 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 CBK23160.2 - 0.0031 17.2 1.2 0.0071 16.0 0.9 1.5 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 CBK23160.2 - 0.022 15.1 4.0 0.052 13.9 2.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CBK23160.2 - 0.033 14.3 2.9 0.07 13.3 2.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Baculo_11_kDa PF06143.6 CBK23160.2 - 0.066 12.5 5.6 0.16 11.3 3.9 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family IncA PF04156.9 CBK23160.2 - 0.19 11.3 1.0 0.29 10.6 0.7 1.2 1 0 0 1 1 1 0 IncA protein HemY_N PF07219.8 CBK23160.2 - 0.36 10.4 0.9 0.78 9.3 0.6 1.5 1 0 0 1 1 1 0 HemY protein N-terminus SP_C-Propep PF08999.5 CBK23160.2 - 0.41 10.1 4.5 0.85 9.1 3.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide LRRC37AB_C PF14914.1 CBK23160.2 - 1.4 8.3 6.9 0.15 11.4 1.5 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain NosD PF05048.8 CBK23162.2 - 0.55 9.3 8.8 0.6 9.2 6.1 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF3139 PF11337.3 CBK23162.2 - 0.98 9.7 7.0 10 6.5 4.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) GST_C PF00043.20 CBK23163.2 - 0.0002 21.3 0.0 0.00031 20.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBK23163.2 - 0.0043 17.4 0.0 0.0054 17.1 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBK23163.2 - 0.029 14.2 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bac_DnaA_C PF08299.6 CBK23163.2 - 0.07 12.9 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix DUF3546 PF12066.3 CBK23165.2 - 1.9e-06 27.8 1.7 5.6e-06 26.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) zf-C2H2 PF00096.21 CBK23165.2 - 8.9e-06 25.7 0.1 3.5e-05 23.8 0.1 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CBK23165.2 - 0.00013 22.0 5.6 0.00018 21.5 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CBK23165.2 - 0.00015 20.4 0.4 0.00023 19.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) ARS2 PF04959.8 CBK23165.2 - 0.00026 21.2 1.4 0.00044 20.5 1.0 1.3 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_2 PF12756.2 CBK23165.2 - 0.00027 21.0 3.0 0.0029 17.7 0.2 2.8 2 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBK23165.2 - 0.0007 19.7 0.3 0.0007 19.7 0.2 2.6 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBK23165.2 - 0.0078 16.0 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger RRM_1 PF00076.17 CBK23165.2 - 0.03 13.9 0.1 1.4 8.5 0.0 3.0 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.2 CBK23165.2 - 0.034 14.3 0.1 0.034 14.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NT5C PF06941.7 CBK23165.2 - 0.069 12.6 1.4 2.4 7.6 0.1 2.4 1 1 1 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) U1snRNP70_N PF12220.3 CBK23165.2 - 0.37 11.1 4.6 4.2 7.7 1.2 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Prefoldin_2 PF01920.15 CBK23165.2 - 1.5 8.5 8.2 0.16 11.7 0.9 2.8 3 0 0 3 3 3 0 Prefoldin subunit SPC25 PF06703.6 CBK23166.2 - 1.6e-11 44.0 0.1 1.9e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) ADH_N PF08240.7 CBK23167.2 - 7.8e-10 38.4 0.3 2.6e-07 30.3 0.0 3.2 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBK23167.2 - 0.0061 16.0 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KH_1 PF00013.24 CBK23169.2 - 7.5e-08 31.9 0.1 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBK23169.2 - 0.0008 19.0 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 KH domain ATP_synt_H PF05493.8 CBK23170.2 - 7.4e-14 51.5 9.4 1.2e-13 50.9 6.5 1.3 1 1 0 1 1 1 1 ATP synthase subunit H DUF4491 PF14898.1 CBK23170.2 - 0.0074 16.4 3.3 0.0083 16.2 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4491) DUF4079 PF13301.1 CBK23170.2 - 0.02 14.9 1.1 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3623 PF12291.3 CBK23170.2 - 0.021 13.8 2.4 0.025 13.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) DUF1772 PF08592.6 CBK23170.2 - 0.066 12.9 1.7 0.074 12.7 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) MARVEL PF01284.18 CBK23170.2 - 0.11 12.3 2.4 0.12 12.1 1.7 1.0 1 0 0 1 1 1 0 Membrane-associating domain DUF2938 PF11158.3 CBK23170.2 - 0.18 11.1 2.5 0.19 11.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) DUF1345 PF07077.6 CBK23170.2 - 0.37 10.2 2.8 0.42 10.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF1129 PF06570.6 CBK23170.2 - 0.59 9.4 2.9 0.68 9.2 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TRP PF06011.7 CBK23170.2 - 0.69 8.4 5.5 0.76 8.2 3.8 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Tmemb_9 PF05434.6 CBK23170.2 - 0.97 9.1 6.9 0.2 11.4 1.4 1.8 1 1 1 2 2 2 0 TMEM9 Flavi_NS4A PF01350.12 CBK23170.2 - 1.1 8.8 5.3 1.2 8.6 3.6 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A SdpI PF13630.1 CBK23170.2 - 4.6 7.0 6.6 6.8 6.4 4.6 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family MgsA_C PF12002.3 CBK23172.2 - 1.7e-56 190.5 0.1 2.7e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CBK23172.2 - 2.9e-06 27.5 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBK23172.2 - 0.0017 17.4 0.1 0.011 14.8 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta2 PF13177.1 CBK23172.2 - 0.02 14.5 0.1 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Sigma54_activat PF00158.21 CBK23172.2 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Atg14 PF10186.4 CBK23173.2 - 9.1e-06 24.8 3.5 1.4e-05 24.2 2.4 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CBK23173.2 - 4.1e-05 22.1 6.2 4.9e-05 21.9 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF3573 PF12097.3 CBK23173.2 - 0.00028 19.6 2.2 0.00036 19.2 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) SYCE1 PF15233.1 CBK23173.2 - 0.00085 19.2 8.4 0.039 13.8 0.2 2.1 1 1 1 2 2 2 2 Synaptonemal complex central element protein 1 TBPIP PF07106.8 CBK23173.2 - 0.00086 18.8 8.3 0.0012 18.4 5.8 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 CBK23173.2 - 0.0047 16.3 7.5 0.0068 15.8 5.2 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) APG6 PF04111.7 CBK23173.2 - 0.0048 15.9 3.8 0.006 15.6 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Fmp27_WPPW PF10359.4 CBK23173.2 - 0.006 15.0 4.1 0.0067 14.9 2.9 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.3 CBK23173.2 - 0.0074 15.5 0.8 0.011 15.0 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Polyoma_lg_T_C PF06431.6 CBK23173.2 - 0.0079 14.8 2.1 0.0097 14.6 1.3 1.3 1 1 0 1 1 1 1 Polyomavirus large T antigen C-terminus Sec5 PF15469.1 CBK23173.2 - 0.0099 15.6 4.6 0.015 15.0 3.2 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 DUF4446 PF14584.1 CBK23173.2 - 0.01 15.6 1.5 0.01 15.6 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Filament PF00038.16 CBK23173.2 - 0.012 15.1 6.7 0.016 14.7 4.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.7 CBK23173.2 - 0.012 15.4 0.8 0.033 13.9 0.4 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBK23173.2 - 0.013 15.0 2.5 0.02 14.5 1.7 1.3 1 0 0 1 1 1 0 IncA protein Apt1 PF10351.4 CBK23173.2 - 0.028 13.3 5.8 0.033 13.0 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1664 PF07889.7 CBK23173.2 - 0.028 14.2 6.9 0.85 9.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.7 CBK23173.2 - 0.029 13.9 6.3 0.04 13.4 3.9 1.6 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Med3 PF11593.3 CBK23173.2 - 0.036 13.3 0.2 0.043 13.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Tweety PF04906.8 CBK23173.2 - 0.056 11.8 1.2 0.056 11.8 0.4 1.4 1 1 0 1 1 1 0 Tweety M_domain PF12938.2 CBK23173.2 - 0.059 13.1 0.2 0.077 12.8 0.1 1.1 1 0 0 1 1 1 0 M domain of GW182 RPW8 PF05659.6 CBK23173.2 - 0.073 12.6 6.2 0.1 12.1 4.0 1.5 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MtrB PF05440.7 CBK23173.2 - 0.083 12.9 2.2 0.22 11.5 1.3 1.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B HOOK PF05622.7 CBK23173.2 - 0.099 10.4 8.2 0.13 10.0 5.7 1.1 1 0 0 1 1 1 0 HOOK protein RmuC PF02646.11 CBK23173.2 - 0.11 11.3 5.6 0.15 10.8 2.6 1.9 2 0 0 2 2 2 0 RmuC family DivIC PF04977.10 CBK23173.2 - 0.11 11.9 9.9 0.19 11.2 3.4 2.7 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 CBK23173.2 - 0.12 12.3 6.3 0.17 11.8 4.4 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF2797 PF10977.3 CBK23173.2 - 0.12 11.9 2.8 0.17 11.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) EMP24_GP25L PF01105.19 CBK23173.2 - 0.13 11.9 5.8 0.16 11.6 3.5 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prefoldin_2 PF01920.15 CBK23173.2 - 0.14 11.9 11.8 1.2 8.8 3.9 2.5 1 1 1 2 2 2 0 Prefoldin subunit Allexi_40kDa PF05549.6 CBK23173.2 - 0.16 11.2 1.8 0.22 10.7 1.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1192 PF06698.6 CBK23173.2 - 0.16 11.8 2.2 3.6 7.4 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS5 PF14817.1 CBK23173.2 - 0.16 10.4 5.2 0.93 7.9 0.9 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 COG5 PF10392.4 CBK23173.2 - 0.2 11.6 4.8 1.2 9.0 0.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Mnd1 PF03962.10 CBK23173.2 - 0.22 11.1 7.8 4.1 7.0 0.6 1.8 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 CBK23173.2 - 0.23 11.9 2.7 8.6 6.8 0.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CYTL1 PF15153.1 CBK23173.2 - 0.25 11.0 3.6 0.51 10.0 1.2 2.0 1 1 0 2 2 2 0 Cytokine-like protein 1 CR6_interact PF10147.4 CBK23173.2 - 0.26 10.5 5.8 0.36 10.1 4.0 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 zf-C4H2 PF10146.4 CBK23173.2 - 0.28 11.1 6.8 0.44 10.5 4.6 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein DUF812 PF05667.6 CBK23173.2 - 0.36 9.2 10.3 1.6 7.1 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Spc24 PF08286.6 CBK23173.2 - 0.37 10.4 9.7 6.4 6.5 6.7 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 CBK23173.2 - 0.38 10.7 11.7 2.5 8.1 3.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 CBK23173.2 - 0.41 11.0 6.1 0.78 10.1 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Fzo_mitofusin PF04799.8 CBK23173.2 - 0.47 9.8 4.8 2.8 7.2 3.2 2.1 1 1 0 1 1 1 0 fzo-like conserved region bZIP_1 PF00170.16 CBK23173.2 - 0.48 10.4 6.7 0.25 11.3 0.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF4164 PF13747.1 CBK23173.2 - 0.51 10.4 4.3 0.85 9.7 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.4 CBK23173.2 - 0.57 9.9 9.0 0.88 9.3 6.0 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Med4 PF10018.4 CBK23173.2 - 0.57 9.5 5.4 1 8.7 3.7 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Med9 PF07544.8 CBK23173.2 - 0.59 9.9 8.1 0.45 10.2 3.6 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 CBK23173.2 - 0.64 10.4 4.6 9.8 6.6 0.8 2.5 1 1 1 2 2 2 0 SlyX DUF2758 PF10957.3 CBK23173.2 - 0.7 9.7 4.7 0.34 10.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) V-SNARE PF05008.10 CBK23173.2 - 0.7 10.0 10.8 1.7 8.8 5.6 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Borrelia_orfD PF02999.9 CBK23173.2 - 0.72 10.0 6.3 7.8 6.6 0.4 3.0 1 1 2 3 3 3 0 Borrelia orf-D family TPR_MLP1_2 PF07926.7 CBK23173.2 - 0.74 9.5 9.2 1.9 8.2 6.3 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 CBK23173.2 - 0.74 9.9 13.0 0.93 9.6 4.1 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2681 PF10883.3 CBK23173.2 - 1 9.6 6.4 1.8 8.7 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) TMF_DNA_bd PF12329.3 CBK23173.2 - 1.1 9.0 13.8 1.4 8.8 4.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 CBK23173.2 - 1.2 9.1 10.2 1.4 8.8 0.3 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 CBK23173.2 - 1.6 8.4 8.8 2 8.1 2.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Tup_N PF08581.5 CBK23173.2 - 2.6 8.2 9.5 5.8 7.1 5.5 2.0 1 1 1 2 2 2 0 Tup N-terminal Nsp1_C PF05064.8 CBK23173.2 - 5.4 6.6 8.6 1.1 8.9 2.0 2.1 2 1 2 4 4 3 0 Nsp1-like C-terminal region Fib_alpha PF08702.5 CBK23173.2 - 6.2 6.9 9.7 14 5.7 2.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4163 PF13739.1 CBK23173.2 - 7.1 7.4 7.2 9.9 7.0 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) MMR_HSR1 PF01926.18 CBK23174.2 - 0.00019 21.3 0.0 0.0012 18.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK23174.2 - 0.043 13.0 0.2 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CBK23174.2 - 0.053 12.6 1.3 0.31 10.1 0.2 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK23174.2 - 0.11 13.0 0.1 1.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 CBK23174.2 - 0.13 12.1 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain fn3 PF00041.16 CBK23175.2 - 7.1e-09 35.6 0.6 0.0003 20.8 0.0 4.9 5 0 0 5 5 5 2 Fibronectin type III domain Big_5 PF13205.1 CBK23175.2 - 4.8e-08 33.5 4.8 1.5e-06 28.7 0.0 4.2 4 0 0 4 4 4 1 Bacterial Ig-like domain HRM PF02793.17 CBK23175.2 - 2.3e-06 27.5 14.6 0.0002 21.2 0.7 21.7 10 4 7 17 17 17 6 Hormone receptor domain CNH PF00780.17 CBK23177.2 - 1.8e-22 80.1 0.0 2.8e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain TPR_11 PF13414.1 CBK23177.2 - 0.028 14.0 0.1 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 CBK23177.2 - 0.15 11.7 0.7 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.4 CBK23178.2 - 7.3e-22 77.6 0.7 2.1e-21 76.1 0.0 2.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 CBK23178.2 - 0.00024 20.7 0.6 0.00024 20.7 0.4 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS Cwf_Cwc_15 PF04889.7 CBK23179.2 - 1.1e-40 139.8 19.8 4.3e-37 128.1 10.0 2.0 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 CBK23179.2 - 0.034 12.5 14.5 0.04 12.2 10.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 CBK23179.2 - 0.035 13.3 8.1 0.038 13.2 5.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HNF-1_N PF04814.8 CBK23179.2 - 0.19 11.7 5.0 0.27 11.3 3.5 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Antigen_Bd37 PF11641.3 CBK23179.2 - 0.56 9.4 5.9 0.87 8.8 4.1 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein PA26 PF04636.8 CBK23179.2 - 0.94 8.0 4.5 1.1 7.8 3.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RD3 PF14473.1 CBK23179.2 - 1.3 8.4 9.0 0.16 11.4 3.4 1.5 2 0 0 2 2 2 0 RD3 protein SseC PF04888.7 CBK23179.2 - 7.2 5.8 6.3 10 5.3 4.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CDC45 PF02724.9 CBK23179.2 - 8.1 4.3 11.3 8.8 4.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GATase_2 PF00310.16 CBK23180.2 - 2.1e-23 82.6 0.0 5.4e-19 68.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CBK23180.2 - 2.8e-14 53.1 0.0 7.2e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBK23180.2 - 1.5e-12 47.3 0.0 3.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CBK23180.2 - 1.1e-08 34.8 0.2 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CBK23180.2 - 1.8e-05 23.6 0.0 2.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA_27 PF13514.1 CBK23180.2 - 0.19 9.3 0.0 0.27 8.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Adap_comp_sub PF00928.16 CBK23181.2 - 2.1e-82 276.2 0.0 2.6e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK23181.2 - 2.9e-09 36.7 0.2 5.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain S_100 PF01023.14 CBK23182.2 - 0.1 11.9 0.2 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Pro_isomerase PF00160.16 CBK23183.2 - 1.9e-44 151.5 0.2 2.1e-44 151.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_8 PF01501.15 CBK23184.2 - 0.044 13.1 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 Metallophos PF00149.23 CBK23185.2 - 2.5e-34 118.4 0.1 3e-34 118.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OTU PF02338.14 CBK23186.2 - 9.1e-21 74.6 0.6 2.2e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBK23186.2 - 5.2e-10 39.1 0.4 5.6e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Transglut_core3 PF13471.1 CBK23186.2 - 0.0078 16.0 0.2 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily GvpL_GvpF PF06386.6 CBK23186.2 - 0.053 13.1 3.5 0.067 12.7 2.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FlaG PF03646.10 CBK23186.2 - 0.078 13.1 7.9 0.13 12.3 5.5 1.3 1 0 0 1 1 1 0 FlaG protein Protocadherin PF08374.6 CBK23186.2 - 0.3 10.7 2.5 0.46 10.0 1.8 1.3 1 0 0 1 1 1 0 Protocadherin DUF2956 PF11169.3 CBK23186.2 - 0.59 10.1 7.5 1 9.3 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Nop25 PF09805.4 CBK23186.2 - 1.8 8.6 15.9 2.6 8.1 10.9 1.4 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Sec62 PF03839.11 CBK23186.2 - 2.9 7.2 6.4 3.9 6.8 4.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Mpp10 PF04006.7 CBK23187.2 - 9.3e-71 238.9 65.1 1.7e-59 201.7 9.3 2.1 2 0 0 2 2 2 2 Mpp10 protein Seryl_tRNA_N PF02403.17 CBK23188.2 - 0.0042 17.0 1.2 0.0042 17.0 0.8 4.8 3 1 2 5 5 5 2 Seryl-tRNA synthetase N-terminal domain SNF2_N PF00176.18 CBK23191.2 - 5.7e-69 232.1 1.6 8.4e-69 231.6 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK23191.2 - 8.4e-15 54.4 0.0 2.3e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBK23191.2 - 1.4e-05 24.0 0.0 0.00032 19.6 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 CBK23191.2 - 0.00024 20.7 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 CBK23191.2 - 0.00036 20.4 0.6 0.004 16.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ycf1 PF05758.7 CBK23191.2 - 0.0052 14.5 2.6 0.01 13.6 1.8 1.4 1 0 0 1 1 1 1 Ycf1 Glyco_trans_4_3 PF12000.3 CBK23191.2 - 0.022 14.4 0.4 0.041 13.4 0.3 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group HGTP_anticodon2 PF12745.2 CBK23191.2 - 5.2 6.1 11.4 9.6 5.2 0.1 2.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs TPR_11 PF13414.1 CBK23192.2 - 1.3e-07 31.1 0.1 3.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CBK23192.2 - 4.5e-07 29.2 0.9 0.02 14.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23192.2 - 1.1e-05 24.8 0.1 0.007 15.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23192.2 - 0.00014 21.6 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23192.2 - 0.0033 18.0 0.0 0.0082 16.7 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK23192.2 - 0.013 15.6 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBK23192.2 - 0.018 14.7 0.3 0.097 12.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23192.2 - 0.031 14.9 0.1 0.14 12.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_32 PF13679.1 CBK23192.2 - 0.22 11.1 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-NF-X1 PF01422.12 CBK23193.2 - 0.01 15.8 11.9 0.01 15.8 8.3 14.0 15 0 0 15 15 15 8 NF-X1 type zinc finger TRAP_alpha PF03896.11 CBK23193.2 - 5.5 5.8 6.8 12 4.8 4.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Acyl-CoA_dh_1 PF00441.19 CBK23194.2 - 8.9e-34 116.7 0.1 1.4e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBK23194.2 - 2.1e-28 99.1 0.1 5.5e-28 97.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBK23194.2 - 1.1e-19 69.6 0.2 2.1e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBK23194.2 - 1e-12 48.4 0.0 1.7e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NIF PF03031.13 CBK23195.2 - 8.5e-20 71.0 0.1 1.7e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CBK23195.2 - 1.4e-10 41.2 0.0 3.4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBK23195.2 - 1.7e-06 27.7 0.0 3.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain CAMSAP_CH PF11971.3 CBK23196.2 - 0.0044 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBK23196.2 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain POR_N PF01855.14 CBK23197.2 - 2.9e-63 213.4 0.2 5e-63 212.6 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK23197.2 - 1.9e-26 93.0 0.0 4.4e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4_7 PF12838.2 CBK23197.2 - 3.1e-11 43.4 0.6 3.1e-05 24.2 9.1 3.4 2 2 3 5 5 5 3 4Fe-4S dicluster domain EKR PF10371.4 CBK23197.2 - 2.1e-10 40.0 0.0 6.5e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.16 CBK23197.2 - 1.1e-08 34.8 1.2 4.7e-08 32.7 0.2 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK23197.2 - 5.5e-05 22.5 12.3 0.00061 19.2 1.1 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.1 CBK23197.2 - 0.00016 21.6 16.2 0.00069 19.5 7.6 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK23197.2 - 0.00018 22.1 17.9 0.003 18.2 2.1 3.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 CBK23197.2 - 0.00033 20.9 14.0 0.00091 19.5 5.0 3.5 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK23197.2 - 0.00061 20.0 17.2 0.012 15.8 2.5 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK23197.2 - 0.0056 16.5 0.0 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_21 PF14697.1 CBK23197.2 - 0.021 14.6 18.9 0.011 15.6 9.5 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK23197.2 - 0.065 13.1 30.0 0.057 13.3 1.5 4.3 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBK23197.2 - 0.09 12.5 21.4 0.024 14.4 9.1 3.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain ABC_tran PF00005.22 CBK23198.2 - 5.8e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK23198.2 - 2.4e-10 40.8 0.0 3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBK23198.2 - 0.0075 15.3 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 CBK23198.2 - 0.015 15.1 0.0 0.1 12.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CBK23198.2 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 CBK23199.2 - 1.2e-15 58.0 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK23199.2 - 2.1e-10 41.0 0.1 4.3e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CBK23199.2 - 0.00083 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBK23199.2 - 0.0015 18.4 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit PGM_PMM_I PF02878.11 CBK23200.2 - 1.7e-28 98.8 0.1 3.3e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CBK23200.2 - 2e-18 66.4 0.0 4.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CBK23200.2 - 2.7e-11 43.6 0.1 2.4e-10 40.6 0.0 2.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CBK23200.2 - 2e-08 34.0 0.0 6.4e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LSM PF01423.17 CBK23201.2 - 1.5e-14 53.3 0.0 2.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain API5 PF05918.6 CBK23201.2 - 0.0059 15.1 4.4 0.0054 15.2 3.0 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) SM-ATX PF14438.1 CBK23201.2 - 0.015 15.2 0.1 0.039 13.8 0.0 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain Caprin-1_C PF12287.3 CBK23201.2 - 0.53 9.6 5.4 0.65 9.3 3.7 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Prefoldin PF02996.12 CBK23202.2 - 2.5e-16 59.3 0.1 3e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CBK23202.2 - 8.9e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBK23202.2 - 0.00088 19.0 0.2 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit Osmo_CC PF08946.5 CBK23202.2 - 0.0012 18.8 1.1 0.013 15.5 0.1 2.1 2 0 0 2 2 2 1 Osmosensory transporter coiled coil Enkurin PF13864.1 CBK23202.2 - 0.066 13.4 0.2 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Calmodulin-binding BLOC1_2 PF10046.4 CBK23202.2 - 0.072 13.2 1.1 9.2 6.4 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4631 PF15450.1 CBK23202.2 - 0.098 10.9 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) HNOB PF07700.10 CBK23202.2 - 0.12 11.8 0.0 8.8 5.8 0.0 2.0 1 1 1 2 2 2 0 Heme NO binding DCX PF03607.12 CBK23202.2 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Doublecortin Bac_surface_Ag PF01103.18 CBK23203.2 - 3.6e-15 56.2 0.0 5.1e-15 55.7 0.0 1.3 1 1 0 1 1 1 1 Surface antigen zf-MYND PF01753.13 CBK23203.2 - 8.5e-11 41.5 12.9 8.5e-11 41.5 8.9 2.0 2 0 0 2 2 2 1 MYND finger DS PF01916.12 CBK23204.2 - 1.3e-129 431.6 0.0 1.5e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 CBK23204.2 - 0.03 13.4 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Methyltransf_11 PF08241.7 CBK23205.2 - 2.9e-11 43.6 0.0 1.1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBK23205.2 - 1.1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK23205.2 - 8.1e-06 25.4 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK23205.2 - 9e-06 26.0 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK23205.2 - 0.00026 21.3 0.1 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK23205.2 - 0.0011 19.5 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 CBK23205.2 - 0.056 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 CBK23205.2 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PHD PF00628.24 CBK23206.2 - 7.9e-15 54.2 5.3 9e-15 54.1 2.8 1.8 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CBK23206.2 - 0.0038 16.9 1.7 0.037 13.7 0.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBK23206.2 - 0.027 13.7 1.0 0.077 12.3 0.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 CBK23206.2 - 0.027 13.7 0.5 0.027 13.7 0.3 1.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-B_box PF00643.19 CBK23206.2 - 0.043 13.7 6.1 0.14 12.1 0.2 2.9 3 0 0 3 3 3 0 B-box zinc finger C1_1 PF00130.17 CBK23206.2 - 0.067 12.9 1.6 0.13 12.0 1.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 CBK23206.2 - 0.14 11.9 3.8 0.31 10.9 2.6 1.6 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.2 CBK23206.2 - 0.15 11.9 6.4 1.7 8.5 4.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon C1_3 PF07649.7 CBK23206.2 - 0.21 11.6 4.0 0.47 10.5 2.8 1.6 1 0 0 1 1 1 0 C1-like domain Prim_Zn_Ribbon PF08273.7 CBK23206.2 - 0.38 10.8 5.3 6.5 6.9 0.1 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DNA_pol_B_2 PF03175.8 CBK23208.2 - 2.8e-09 36.1 7.6 0.0012 17.6 0.2 3.5 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral Thioredoxin PF00085.15 CBK23210.2 - 7.3e-19 67.3 0.0 2.6e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 CBK23210.2 - 1.9e-17 63.6 0.1 3.2e-13 49.8 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK23210.2 - 2.1e-05 24.6 0.5 0.00086 19.4 0.4 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CBK23210.2 - 0.00016 21.4 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 CBK23210.2 - 0.099 12.6 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like FKBP_C PF00254.23 CBK23212.2 - 1.5e-27 95.3 0.0 4.1e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIF_alpha PF05793.7 CBK23212.2 - 0.00067 18.1 36.0 0.00087 17.7 25.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mitofilin PF09731.4 CBK23212.2 - 0.0025 16.5 21.4 0.0031 16.2 14.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein HSP70 PF00012.15 CBK23212.2 - 0.0041 15.0 16.6 0.0048 14.8 11.5 1.0 1 0 0 1 1 1 1 Hsp70 protein SprA-related PF12118.3 CBK23212.2 - 0.0063 15.8 18.1 0.0076 15.6 12.5 1.1 1 0 0 1 1 1 1 SprA-related family Ycf1 PF05758.7 CBK23212.2 - 0.0068 14.2 16.5 0.007 14.1 11.5 1.2 1 0 0 1 1 1 1 Ycf1 CDC45 PF02724.9 CBK23212.2 - 0.01 13.8 26.3 0.014 13.5 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CBK23212.2 - 0.011 13.6 42.6 0.015 13.2 29.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CBK23212.2 - 0.03 13.5 23.5 0.037 13.2 16.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SAPS PF04499.10 CBK23212.2 - 0.04 12.5 12.2 0.049 12.2 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 CBK23212.2 - 0.054 11.9 39.2 0.075 11.5 27.2 1.1 1 0 0 1 1 1 0 Daxx Family Pilt PF15453.1 CBK23212.2 - 0.058 13.0 14.2 0.073 12.7 9.8 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SDA1 PF05285.7 CBK23212.2 - 0.059 12.6 39.4 0.078 12.2 27.3 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.6 CBK23212.2 - 0.078 11.9 33.9 0.11 11.4 23.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Raftlin PF15250.1 CBK23212.2 - 0.086 11.3 10.2 0.1 11.0 7.1 1.2 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 CBK23212.2 - 0.095 11.1 39.1 0.12 10.8 27.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 CBK23212.2 - 0.15 11.5 16.8 0.22 10.9 11.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAGA_bind PF06217.7 CBK23212.2 - 0.16 11.9 10.2 0.21 11.5 7.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CBK23212.2 - 0.17 11.0 16.4 0.23 10.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CBK23212.2 - 0.27 10.3 14.8 0.34 10.0 10.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AvrE PF11725.3 CBK23212.2 - 0.5 7.3 7.7 0.55 7.1 5.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF966 PF06136.8 CBK23212.2 - 0.59 9.4 13.2 0.88 8.9 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mpp10 PF04006.7 CBK23212.2 - 0.87 7.8 44.2 1.1 7.4 30.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Hid1 PF12722.2 CBK23212.2 - 0.93 7.0 12.1 1.1 6.8 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TATR PF03430.8 CBK23212.2 - 0.94 8.0 9.1 1.1 7.8 6.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Zip PF02535.17 CBK23212.2 - 1 8.3 11.0 1.3 7.9 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CBK23212.2 - 1.2 8.5 38.5 1.7 7.9 26.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CBK23212.2 - 1.9 8.2 32.6 2.9 7.7 22.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 CBK23212.2 - 2.1 7.2 18.4 2.3 7.0 12.2 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Caldesmon PF02029.10 CBK23212.2 - 2.1 6.6 41.8 3 6.1 29.0 1.1 1 0 0 1 1 1 0 Caldesmon RNA_polI_A34 PF08208.6 CBK23212.2 - 2.3 7.8 36.6 4.3 6.9 25.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Tim54 PF11711.3 CBK23212.2 - 3.1 6.3 21.1 5.2 5.5 14.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Merozoite_SPAM PF07133.6 CBK23212.2 - 3.1 7.6 52.9 5.6 6.8 36.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2151 PF10221.4 CBK23212.2 - 3.6 5.6 13.3 4 5.5 9.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2201_N PF13203.1 CBK23212.2 - 3.8 6.6 12.7 5.1 6.1 8.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Mem_trans PF03547.13 CBK23212.2 - 6.3 4.9 8.8 8.1 4.6 6.1 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC27 PF09507.5 CBK23212.2 - 8.4 5.4 37.5 12 4.9 26.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Drc1-Sld2 PF11719.3 CBK23212.2 - 9.7 5.1 24.6 14 4.6 17.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Paramyxo_ncap PF00973.14 CBK23212.2 - 9.7 4.7 9.5 12 4.4 6.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glyco_transf_49 PF13896.1 CBK23214.2 - 1.6e-07 30.7 0.2 1.7e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DEAD PF00270.24 CBK23215.2 - 1.9e-35 121.8 0.0 4.2e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23215.2 - 6.6e-24 83.5 0.0 2.1e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBK23215.2 - 1.3e-12 47.0 1.0 4.8e-11 42.0 0.1 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.9 CBK23215.2 - 0.027 13.7 5.1 0.1 11.8 0.0 3.2 3 0 0 3 3 3 0 SecA DEAD-like domain AAA_22 PF13401.1 CBK23215.2 - 0.058 13.5 1.5 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF3658 PF12395.3 CBK23215.2 - 0.14 11.6 6.5 0.12 11.9 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function Patched PF02460.13 CBK23216.2 - 2.6e-25 88.5 15.1 2.6e-25 88.5 10.5 2.5 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 CBK23216.2 - 1.2e-05 24.8 9.4 2.6e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation HTH_16 PF12645.2 CBK23216.2 - 0.0079 16.1 0.4 0.016 15.1 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain LSM PF01423.17 CBK23217.2 - 3.6e-08 32.8 0.1 5.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBK23217.2 - 0.0058 16.5 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4522 PF15022.1 CBK23217.2 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) CedA PF10729.4 CBK23217.2 - 0.14 11.7 0.1 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 Cell division activator CedA RRM_1 PF00076.17 CBK23218.2 - 1.3e-14 53.5 0.3 0.00025 20.6 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23218.2 - 1.7e-09 37.4 0.0 0.0025 17.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23218.2 - 0.00032 20.4 0.0 0.0082 15.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps51 PF08700.6 CBK23219.2 - 2.1e-13 49.8 0.3 3.9e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Sec8_exocyst PF04048.9 CBK23219.2 - 0.00085 18.9 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 CBK23219.2 - 0.036 13.9 0.1 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dam1 PF08653.5 CBK23219.2 - 0.094 12.5 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Dna2 PF08696.6 CBK23221.2 - 4.4e-28 98.0 0.0 3.5e-27 95.1 0.0 2.1 1 1 0 1 1 1 1 DNA replication factor Dna2 Cas_Cas4 PF01930.12 CBK23221.2 - 0.015 15.2 1.8 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF83 AAA_12 PF13087.1 CBK23222.2 - 4.9e-50 169.7 0.7 4.9e-50 169.7 0.5 1.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBK23222.2 - 4.4e-32 111.5 1.8 3.9e-16 59.3 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 CBK23222.2 - 2.4e-12 46.8 0.0 1.3e-11 44.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CBK23222.2 - 2.9e-09 36.8 0.2 0.0052 16.3 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBK23222.2 - 6.7e-08 32.1 0.0 4.5e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Helicase_RecD PF05127.9 CBK23222.2 - 4.7e-05 23.0 0.0 0.00016 21.3 0.0 2.0 1 1 0 1 1 1 1 Helicase PhoH PF02562.11 CBK23222.2 - 0.0048 16.1 0.2 0.027 13.6 0.0 2.3 2 1 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.1 CBK23222.2 - 0.017 15.2 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 CBK23222.2 - 0.068 12.1 0.0 0.26 10.2 0.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CBK23222.2 - 0.1 12.4 0.0 0.95 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 CBK23222.2 - 0.12 11.8 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 CBK23222.2 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3524 PF12038.3 CBK23223.2 - 2.4e-52 176.9 0.0 3.8e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.15 CBK23223.2 - 1.4e-09 37.5 0.0 3.6e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBK23223.2 - 1.1e-07 32.0 0.0 4.6e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 G3P_antiterm PF04309.7 CBK23223.2 - 0.065 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Mnd1 PF03962.10 CBK23224.2 - 0.00041 20.0 9.1 0.00059 19.5 6.3 1.2 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 CBK23224.2 - 0.0089 15.6 7.3 0.012 15.2 5.0 1.3 1 0 0 1 1 1 1 IncA protein HAP1_N PF04849.8 CBK23224.2 - 0.031 13.2 10.9 0.032 13.1 6.5 1.7 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF1258 PF06869.7 CBK23224.2 - 0.038 13.0 0.5 0.11 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) SlyX PF04102.7 CBK23224.2 - 0.048 14.0 6.9 3.8 7.9 2.4 2.6 1 1 1 2 2 2 0 SlyX Senescence_reg PF04520.8 CBK23224.2 - 0.077 13.4 1.2 0.098 13.1 0.8 1.2 1 0 0 1 1 1 0 Senescence regulator DUF1635 PF07795.6 CBK23224.2 - 0.08 12.3 5.5 0.12 11.7 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TP53IP5 PF15331.1 CBK23224.2 - 0.16 11.8 6.4 0.25 11.2 4.5 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4559 PF15112.1 CBK23224.2 - 0.19 10.8 6.4 0.27 10.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CALCOCO1 PF07888.6 CBK23224.2 - 0.22 9.7 10.8 0.25 9.5 7.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Herpes_UL6 PF01763.11 CBK23224.2 - 0.24 9.5 4.2 0.36 8.9 2.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Allexi_40kDa PF05549.6 CBK23224.2 - 0.29 10.3 3.6 0.41 9.9 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein AAA_13 PF13166.1 CBK23224.2 - 0.4 9.0 10.4 0.49 8.8 7.2 1.1 1 0 0 1 1 1 0 AAA domain Prp18 PF02840.10 CBK23224.2 - 0.41 10.4 4.9 0.64 9.8 3.4 1.3 1 0 0 1 1 1 0 Prp18 domain ADIP PF11559.3 CBK23224.2 - 0.49 10.2 12.5 0.76 9.6 8.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 CBK23224.2 - 0.77 8.0 8.2 0.93 7.8 5.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-Q PF13094.1 CBK23224.2 - 0.8 9.7 16.5 3.5 7.6 11.4 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 CBK23224.2 - 0.96 7.2 7.0 1.2 6.9 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 CBK23224.2 - 1 9.5 14.7 2 8.6 10.2 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3373 PF11853.3 CBK23224.2 - 1.1 7.6 4.8 1.2 7.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2951 PF11166.3 CBK23224.2 - 1.8 8.5 10.3 3.4 7.5 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DivIC PF04977.10 CBK23224.2 - 1.8 8.0 11.5 5.7 6.4 3.7 2.4 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CBK23224.2 - 2.2 7.1 10.2 3.1 6.6 7.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 CBK23224.2 - 2.4 8.1 14.3 1.9 8.5 2.9 2.5 1 1 1 2 2 2 0 bZIP transcription factor CAF1C_H4-bd PF12265.3 CBK23227.2 - 2.4e-14 52.9 0.8 4.6e-14 52.0 0.5 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GH97_C PF14509.1 CBK23227.2 - 0.07 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF3688 PF12461.3 CBK23227.2 - 0.42 11.0 3.7 0.17 12.3 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3688) Myb_DNA-binding PF00249.26 CBK23228.2 - 1.5e-05 24.9 0.0 4.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Gly_acyl_tr_N PF06021.6 CBK23228.2 - 0.066 12.6 0.2 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Myb_DNA-bind_6 PF13921.1 CBK23228.2 - 0.31 11.1 1.9 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain T2SK PF03934.8 CBK23229.2 - 0.065 12.3 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Methyltransf_32 PF13679.1 CBK23230.2 - 2.1e-10 40.4 1.9 2.9e-10 39.9 1.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain potato_inhibit PF00280.13 CBK23231.2 - 3.7e-14 52.6 0.3 4e-14 52.4 0.2 1.0 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.3 CBK23231.2 - 0.00015 21.3 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family tRNA-synt_1d PF00750.14 CBK23232.2 - 9.3e-103 343.7 0.0 1.2e-102 343.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBK23232.2 - 4.4e-31 107.3 0.0 1.1e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CBK23232.2 - 7.1e-17 61.7 0.0 6.2e-15 55.5 0.0 2.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 CBK23232.2 - 0.00012 21.2 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBK23232.2 - 0.0022 16.7 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) SBP_bac_5 PF00496.17 CBK23232.2 - 0.05 12.4 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle OTCace_N PF02729.16 CBK23233.2 - 1.2e-37 128.6 0.0 1.8e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CBK23233.2 - 9.1e-15 54.8 0.0 2.2e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DnaJ PF00226.26 CBK23234.2 - 2.3e-22 78.5 0.6 4.1e-22 77.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBK23234.2 - 1e-17 63.7 0.0 3.1e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBK23234.2 - 1.8e-10 40.6 5.9 4.4e-10 39.4 4.1 1.6 1 1 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBK23234.2 - 0.00073 19.2 5.0 0.056 13.1 0.4 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 CBK23234.2 - 0.024 14.2 2.4 0.13 11.9 1.8 2.1 1 1 0 1 1 1 0 Cytochrome c7 DUF4265 PF14085.1 CBK23234.2 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Cytochrom_c3_2 PF14537.1 CBK23234.2 - 0.16 12.3 1.8 0.42 10.9 1.1 1.9 1 1 0 1 1 1 0 Cytochrome c3 DUF3353 PF11833.3 CBK23234.2 - 0.31 10.4 0.7 0.55 9.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Zn-ribbon_8 PF09723.5 CBK23234.2 - 0.5 10.3 5.3 17 5.4 0.4 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Vps39_2 PF10367.4 CBK23234.2 - 0.67 10.1 3.7 17 5.6 0.1 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Cytochrome_CBB3 PF13442.1 CBK23234.2 - 2.9 8.1 5.6 31 4.8 0.4 3.0 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III HA2 PF04408.18 CBK23235.2 - 6.4e-19 67.8 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK23235.2 - 6.7e-17 61.3 0.0 1.8e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK23235.2 - 1.1e-13 50.8 0.0 3.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK23235.2 - 1e-06 28.3 0.0 4.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK23235.2 - 0.0051 16.9 0.1 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CBK23235.2 - 0.015 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 CBK23235.2 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CBK23235.2 - 0.087 12.7 0.0 2 8.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBK23235.2 - 0.088 12.5 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2_jaz PF12171.3 CBK23236.2 - 0.25 11.5 1.7 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HIT PF01230.18 CBK23237.2 - 1.9e-25 89.2 0.0 2.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBK23237.2 - 6.2e-22 78.0 0.1 8.4e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding His_biosynth PF00977.16 CBK23237.2 - 0.083 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein KTI12 PF08433.5 CBK23238.2 - 5.4e-59 199.6 2.2 1.4e-58 198.2 1.5 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CBK23238.2 - 2.3e-08 34.0 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK23238.2 - 0.00034 21.4 0.0 0.00058 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CBK23238.2 - 0.00054 19.5 0.1 0.0016 17.9 0.0 1.9 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CBK23238.2 - 0.0009 19.1 0.1 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CBK23238.2 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 CBK23238.2 - 0.066 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain BK_channel_a PF03493.13 CBK23238.2 - 0.091 12.7 1.0 3.1 7.7 0.1 2.6 2 1 1 3 3 3 0 Calcium-activated BK potassium channel alpha subunit Zeta_toxin PF06414.7 CBK23238.2 - 0.096 11.7 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ER_lumen_recept PF00810.13 CBK23239.2 - 5.2e-32 111.3 6.6 5.2e-32 111.3 4.6 2.0 2 1 0 2 2 2 1 ER lumen protein retaining receptor Herpes_U26 PF07402.6 CBK23239.2 - 0.00043 19.6 1.0 0.00079 18.8 0.7 1.4 1 0 0 1 1 1 1 Human herpesvirus U26 protein Metallophos PF00149.23 CBK23240.2 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK23240.2 - 0.00037 20.3 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MORN PF02493.15 CBK23241.2 - 0.0061 16.2 2.5 0.0061 16.2 1.7 6.0 8 0 0 8 8 8 1 MORN repeat Chordopox_G2 PF05796.7 CBK23241.2 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 MORN_2 PF07661.8 CBK23241.2 - 0.7 10.1 6.9 8.7 6.7 0.0 4.6 6 0 0 6 6 6 0 MORN repeat variant SNARE PF05739.14 CBK23242.2 - 9.5e-10 38.0 4.7 9.8e-10 37.9 3.3 1.0 1 0 0 1 1 1 1 SNARE domain Ras PF00071.17 CBK23243.2 - 5.3e-41 139.7 0.0 6.3e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBK23243.2 - 3e-15 55.9 0.0 3.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBK23243.2 - 7e-14 52.3 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBK23243.2 - 2.8e-09 36.7 0.0 2.9e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBK23243.2 - 9.6e-07 28.1 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK23243.2 - 0.0003 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK23243.2 - 0.0036 16.6 0.0 0.16 11.2 0.0 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CBK23243.2 - 0.0075 15.4 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBK23243.2 - 0.057 13.5 0.0 0.3 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain Beta_elim_lyase PF01212.16 CBK23244.2 - 7.7e-75 251.7 0.0 1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 CBK23244.2 - 7.5e-05 21.3 0.0 0.00012 20.6 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 CBK23244.2 - 0.0047 15.9 0.0 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 CBK23244.2 - 0.0061 15.0 0.0 0.01 14.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ABC1 PF03109.11 CBK23245.2 - 2.5e-32 111.3 0.3 9.9e-32 109.4 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 CBK23245.2 - 0.024 14.3 0.0 1.4 8.6 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FKBP_N PF01346.13 CBK23245.2 - 0.63 10.1 3.1 1.2 9.2 2.1 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AAA PF00004.24 CBK23246.2 - 2.6e-38 131.1 0.0 6.2e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK23246.2 - 1.6e-06 28.3 0.1 0.00021 21.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK23246.2 - 4.2e-06 26.5 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK23246.2 - 1.6e-05 24.0 0.0 8.1e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBK23246.2 - 2e-05 24.5 0.0 7.4e-05 22.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBK23246.2 - 3.6e-05 23.8 0.8 0.043 13.7 0.0 3.3 1 1 2 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CBK23246.2 - 3.6e-05 23.2 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBK23246.2 - 4.8e-05 22.2 0.1 0.00017 20.4 0.0 1.9 2 1 1 3 3 3 1 TIP49 C-terminus AAA_25 PF13481.1 CBK23246.2 - 6e-05 22.5 0.9 0.11 11.8 0.2 3.5 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.1 CBK23246.2 - 6e-05 23.8 0.5 0.00078 20.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK23246.2 - 0.00013 21.8 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK23246.2 - 0.00016 22.0 0.6 0.00075 19.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 CBK23246.2 - 0.00029 20.7 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CBK23246.2 - 0.0015 17.7 0.2 0.0041 16.3 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBK23246.2 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBK23246.2 - 0.0093 16.0 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CBK23246.2 - 0.011 15.9 0.0 0.048 13.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_19 PF13245.1 CBK23246.2 - 0.014 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CBK23246.2 - 0.024 14.3 0.1 0.25 10.9 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CBK23246.2 - 0.029 13.4 0.0 0.065 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 CBK23246.2 - 0.041 13.5 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 CBK23246.2 - 0.065 12.8 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_10 PF12846.2 CBK23246.2 - 0.07 12.5 0.1 3.5 6.9 0.0 2.8 1 1 1 2 2 2 0 AAA-like domain AAA_24 PF13479.1 CBK23246.2 - 0.097 12.2 0.7 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBK23246.2 - 0.14 11.3 0.1 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Trypan_PARP PF05887.6 CBK23246.2 - 1 9.1 5.5 0.19 11.5 0.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) eIF-3_zeta PF05091.7 CBK23247.2 - 0.36 9.4 3.3 0.4 9.2 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Oxidored_FMN PF00724.15 CBK23248.2 - 3.3e-72 243.3 0.0 4.1e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family S_100 PF01023.14 CBK23248.2 - 0.086 12.1 0.0 0.28 10.5 0.0 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain PCI PF01399.22 CBK23249.2 - 7.9e-09 35.7 0.8 9.7e-09 35.5 0.6 1.1 1 0 0 1 1 1 1 PCI domain Rrp15p PF07890.7 CBK23250.2 - 1.9e-11 44.1 18.7 1.9e-11 44.1 10.3 2.3 1 1 1 2 2 2 1 Rrp15p Mif2_N PF15624.1 CBK23250.2 - 1.8 9.1 10.3 0.24 11.9 3.8 1.9 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Hist_deacetyl PF00850.14 CBK23251.2 - 1.2e-77 261.2 0.0 1.8e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.20 CBK23252.2 - 1.4e-50 171.8 0.0 1.4e-50 171.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23252.2 - 4.9e-21 74.9 0.2 1.1e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23252.2 - 0.015 14.3 0.1 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.11 CBK23253.2 - 5.9e-28 97.5 13.8 5.9e-28 97.5 9.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK23253.2 - 6.8e-18 64.4 18.0 1.2e-17 63.6 12.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PigN PF04987.9 CBK23253.2 - 0.00018 20.2 8.9 0.00018 20.2 6.2 2.2 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) PIRT PF15099.1 CBK23253.2 - 4 6.6 7.7 6.3 6.0 1.1 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Lig_chan PF00060.21 CBK23253.2 - 5 6.8 10.2 27 4.4 0.0 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel MFS_1 PF07690.11 CBK23254.2 - 4.7e-12 45.2 43.0 1.4e-07 30.5 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu_cyclase_2 PF05096.7 CBK23255.2 - 7.6e-29 100.5 0.2 9.6e-29 100.2 0.2 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SBBP PF06739.6 CBK23255.2 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat MFS_1 PF07690.11 CBK23256.2 - 5.6e-15 54.9 42.7 1.3e-12 47.1 9.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu_cyclase_2 PF05096.7 CBK23257.2 - 8.4e-43 146.2 0.2 1.1e-42 145.9 0.1 1.1 1 0 0 1 1 1 1 Glutamine cyclotransferase PFK PF00365.15 CBK23261.2 - 3.3e-13 49.2 0.0 1.8e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Phosphofructokinase VPS28 PF03997.7 CBK23262.2 - 0.13 11.9 4.8 0.3 10.6 0.4 2.2 1 1 1 2 2 2 0 VPS28 protein Amelogenin PF02948.10 CBK23262.2 - 4.2 7.9 6.5 2.1 8.9 1.9 1.9 1 1 1 2 2 2 0 Amelogenin Dynamin_N PF00350.18 CBK23263.2 - 1.2e-19 70.7 0.0 2.4e-18 66.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 CBK23263.2 - 1.1e-18 66.9 0.7 3.9e-18 65.1 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 CBK23263.2 - 8.6e-10 38.5 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 CBK23263.2 - 0.00034 19.6 0.3 0.0014 17.7 0.1 2.2 2 0 0 2 2 2 1 EF hand Miro PF08477.8 CBK23263.2 - 0.00043 20.7 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CBK23263.2 - 0.00076 18.9 0.0 0.0023 17.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBK23263.2 - 0.002 17.2 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBK23263.2 - 0.011 15.8 0.0 0.038 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain EF-hand_6 PF13405.1 CBK23263.2 - 0.069 13.0 0.0 0.87 9.6 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain AIG1 PF04548.11 CBK23263.2 - 0.12 11.5 0.0 0.32 10.0 0.0 1.7 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.1 CBK23263.2 - 0.17 11.8 0.1 2.4 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 CBK23264.2 - 1.5e-30 103.9 10.1 1.4e-05 24.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Rav1p_C PF12234.3 CBK23265.2 - 5.4e-33 114.0 7.0 7.3e-32 110.3 1.2 2.2 2 0 0 2 2 2 2 RAVE protein 1 C terminal WT1 PF02165.10 CBK23266.2 - 0.012 14.7 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 Wilm's tumour protein AAA PF00004.24 CBK23267.2 - 4e-45 153.2 0.0 1e-44 151.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK23267.2 - 2.9e-08 33.5 0.1 7.8e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBK23267.2 - 3.6e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBK23267.2 - 7.5e-07 29.3 0.2 0.00039 20.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBK23267.2 - 4.6e-05 22.4 0.0 9e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBK23267.2 - 8.9e-05 21.6 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBK23267.2 - 0.00012 22.1 0.0 0.0013 18.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CBK23267.2 - 0.00024 20.3 0.2 0.00064 18.9 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBK23267.2 - 0.00032 21.4 0.0 0.0021 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK23267.2 - 0.00039 20.7 0.0 0.003 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBK23267.2 - 0.00042 19.4 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CBK23267.2 - 0.00044 20.1 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK23267.2 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBK23267.2 - 0.0011 18.3 0.1 0.0032 16.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBK23267.2 - 0.0013 18.4 0.1 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CBK23267.2 - 0.0024 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK23267.2 - 0.0025 16.6 0.0 0.0051 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 CBK23267.2 - 0.0034 16.8 0.1 0.1 12.0 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 CBK23267.2 - 0.0063 16.1 0.6 0.04 13.5 0.0 2.5 2 1 1 3 3 2 1 NACHT domain AAA_24 PF13479.1 CBK23267.2 - 0.0064 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 CBK23267.2 - 0.0085 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CBK23267.2 - 0.011 15.8 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 CBK23267.2 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBK23267.2 - 0.019 14.4 1.2 0.11 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 CBK23267.2 - 0.021 13.9 0.3 0.32 10.0 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.6 CBK23267.2 - 0.033 13.8 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBK23267.2 - 0.036 14.1 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CBK23267.2 - 0.042 13.0 0.1 0.11 11.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 CBK23267.2 - 0.057 13.1 0.0 0.8 9.3 0.0 2.2 1 1 0 2 2 2 0 Archaeal ATPase Bac_DnaA PF00308.13 CBK23267.2 - 0.058 13.0 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein NTPase_1 PF03266.10 CBK23267.2 - 0.078 12.6 0.9 3.8 7.2 0.0 3.1 2 1 1 3 3 3 0 NTPase NB-ARC PF00931.17 CBK23267.2 - 0.086 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 CBK23267.2 - 0.098 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.16 CBK23267.2 - 0.11 11.9 0.1 7.8 5.9 0.0 2.9 3 0 0 3 3 3 0 Guanylate kinase DUF89 PF01937.14 CBK23268.2 - 4.6e-58 196.7 0.0 5.1e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ribosomal_L1 PF00687.16 CBK23269.2 - 9.4e-34 116.6 1.7 9.4e-34 116.6 1.2 2.8 1 1 2 3 3 3 1 Ribosomal protein L1p/L10e family CDC45 PF02724.9 CBK23269.2 - 0.012 13.7 10.9 0.017 13.1 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CBK23269.2 - 0.38 8.3 17.6 0.49 8.0 12.2 1.1 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 CBK23269.2 - 0.41 9.0 28.5 0.62 8.4 19.8 1.2 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 CBK23269.2 - 0.68 9.4 39.2 1.6 8.2 27.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Spt5_N PF11942.3 CBK23269.2 - 4.1 8.0 23.7 12 6.6 16.5 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2201_N PF13203.1 CBK23269.2 - 9.1 5.3 8.9 13 4.8 6.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-C3HC4_2 PF13923.1 CBK23270.2 - 6.4e-12 45.2 12.0 1.1e-11 44.4 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK23270.2 - 9.5e-11 41.3 13.0 1.4e-10 40.7 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBK23270.2 - 1.5e-10 40.5 7.8 2.4e-10 39.9 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23270.2 - 5.7e-10 38.6 9.5 9.8e-10 37.9 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23270.2 - 2.6e-07 30.2 9.2 7.3e-07 28.8 6.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBK23270.2 - 6.8e-06 25.8 12.3 1.4e-05 24.8 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBK23270.2 - 5e-05 22.9 4.0 5e-05 22.9 2.8 3.0 3 0 0 3 3 3 1 RING-type zinc-finger Rtf2 PF04641.7 CBK23270.2 - 0.014 14.6 0.5 0.017 14.3 0.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.2 CBK23270.2 - 0.022 14.8 9.9 0.044 13.8 6.8 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CBK23270.2 - 0.024 14.1 10.1 0.074 12.6 7.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 CBK23270.2 - 0.026 14.4 0.0 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-RING_6 PF14835.1 CBK23270.2 - 0.03 14.0 5.7 0.048 13.4 4.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CBK23270.2 - 0.11 12.3 5.3 0.18 11.6 3.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 CBK23270.2 - 0.12 12.0 4.6 0.21 11.3 3.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBK23270.2 - 0.13 11.8 8.1 0.27 10.8 5.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 CBK23270.2 - 2.9 7.8 10.1 9.3 6.2 7.1 1.9 1 1 0 1 1 1 0 IBR domain DUF1644 PF07800.7 CBK23270.2 - 3.4 7.4 6.8 10 5.9 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-C4_ClpX PF06689.8 CBK23271.2 - 0.063 12.8 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger HSP70 PF00012.15 CBK23272.2 - 3.4e-88 296.0 0.1 7.2e-81 271.8 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK23272.2 - 1.4e-13 50.1 0.1 1.4e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.15 CBK23272.2 - 0.059 12.6 0.0 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UPF0160 PF03690.8 CBK23273.2 - 4.6e-119 397.5 0.0 5.2e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endonuclease_5 PF04493.9 CBK23274.2 - 4.4e-37 127.4 0.0 9e-37 126.4 0.0 1.5 1 1 1 2 2 2 1 Endonuclease V Ribosomal_L25p PF01386.14 CBK23275.2 - 9.1e-13 48.1 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.1 CBK23275.2 - 0.0022 18.1 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L15e PF00827.12 CBK23276.2 - 4.1e-80 267.8 10.5 5.7e-79 264.0 7.3 1.9 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L16 PF00252.13 CBK23277.2 - 8.2e-31 106.5 0.2 1e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.3 CBK23277.2 - 0.14 11.8 0.3 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ribosomal_S16 PF00886.14 CBK23278.2 - 3.2e-25 87.6 0.0 4.2e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L24e PF01246.15 CBK23279.2 - 9.8e-32 108.6 1.7 9.8e-32 108.6 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e CDK5_activator PF03261.10 CBK23279.2 - 0.21 10.8 9.3 0.24 10.7 6.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2175 PF09943.4 CBK23279.2 - 3.9 7.6 14.5 0.11 12.5 0.6 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TAF8_C PF10406.4 CBK23279.2 - 4.8 7.3 5.4 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term TPT PF03151.11 CBK23280.2 - 3.2e-17 62.5 5.5 3.5e-17 62.4 3.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.6 CBK23280.2 - 5.7e-07 28.7 2.1 6.5e-07 28.5 1.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBK23280.2 - 9.9e-06 25.6 5.2 1.2e-05 25.3 3.6 1.1 1 0 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 CBK23280.2 - 0.00065 19.8 3.9 0.00078 19.6 2.7 1.1 1 0 0 1 1 1 1 Multidrug resistance efflux transporter Mg_trans_NIPA PF05653.9 CBK23280.2 - 0.00065 18.7 3.8 0.00074 18.5 2.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Transgly_assoc PF04226.8 CBK23280.2 - 0.47 10.5 4.6 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein adh_short PF00106.20 CBK23281.2 - 8e-09 35.6 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 CBK23282.2 - 4.5e-12 46.1 0.0 5.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBK23282.2 - 2e-06 27.6 0.0 2.2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CBK23282.2 - 0.0002 20.5 0.2 0.00023 20.3 0.1 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBK23282.2 - 0.00028 20.5 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 CBK23282.2 - 0.00044 20.0 0.1 0.00051 19.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CBK23282.2 - 0.0025 17.5 0.2 0.0074 16.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UDPG_MGDP_dh_N PF03721.9 CBK23282.2 - 0.0059 16.0 0.0 0.0081 15.5 0.0 1.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CagE_TrbE_VirB PF03135.9 CBK23282.2 - 0.02 14.6 0.1 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system NAD_Gly3P_dh_N PF01210.18 CBK23282.2 - 0.027 14.2 0.1 0.038 13.7 0.1 1.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3335 PF11814.3 CBK23282.2 - 0.04 13.0 0.1 0.053 12.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family Oxidored_nitro PF00148.14 CBK23282.2 - 0.045 12.3 0.1 0.067 11.8 0.0 1.4 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.16 CBK23282.2 - 0.05 13.1 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 CBK23282.2 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain XdhC_C PF13478.1 CBK23282.2 - 0.1 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 XdhC Rossmann domain DUF458 PF04308.7 CBK23282.2 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF458) Nuc_sug_transp PF04142.10 CBK23283.2 - 8.5e-68 228.0 18.6 1.5e-67 227.2 12.9 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CBK23283.2 - 4e-06 26.8 29.8 3.8e-05 23.7 3.6 3.1 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBK23283.2 - 0.0003 20.4 8.1 0.0003 20.4 5.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 CBK23283.2 - 0.0052 16.9 4.1 0.0052 16.9 2.8 3.5 1 1 3 4 4 4 2 Multidrug resistance efflux transporter Orthopox_A47 PF06334.6 CBK23283.2 - 0.12 11.4 1.6 1.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Orthopoxvirus A47 protein DUF1195 PF06708.6 CBK23283.2 - 0.19 11.1 0.8 0.41 10.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) ELMO_CED12 PF04727.8 CBK23284.2 - 9.7e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family RhoGAP PF00620.22 CBK23284.2 - 9.1e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Dor1 PF04124.7 CBK23285.2 - 1.4e-23 82.9 5.2 2.1e-23 82.3 3.6 1.2 1 0 0 1 1 1 1 Dor1-like family TBPIP PF07106.8 CBK23285.2 - 0.058 12.9 2.2 0.091 12.2 1.5 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RasGAP PF00616.14 CBK23285.2 - 0.059 13.0 2.5 0.088 12.4 1.7 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase TPR_12 PF13424.1 CBK23285.2 - 0.098 12.6 0.2 7.6 6.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C PF00271.26 CBK23286.2 - 5.1e-11 42.2 0.0 1.9e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBK23286.2 - 4.6e-06 26.5 0.0 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CBK23286.2 - 7.6e-05 22.2 0.1 0.00018 21.0 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 CBK23286.2 - 0.075 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBK23286.2 - 0.098 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CBK23286.2 - 0.14 12.5 0.1 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 CBK23287.2 - 9.1e-08 31.6 2.1 1.1e-07 31.3 0.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBK23287.2 - 0.034 14.1 0.4 0.084 12.9 0.3 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type YolD PF08863.5 CBK23287.2 - 1.9 8.4 5.1 19 5.1 0.5 2.5 2 0 0 2 2 2 0 YolD-like protein Bac_rhamnosid_N PF08531.5 CBK23291.2 - 0.11 11.9 0.3 5.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Alpha-L-rhamnosidase N-terminal domain SF-assemblin PF06705.6 CBK23292.2 - 0.12 11.5 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DDHD PF02862.12 CBK23293.2 - 0.072 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 DDHD domain AdoHcyase PF05221.12 CBK23294.2 - 2.1e-118 394.1 0.0 2.4e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBK23294.2 - 1.2e-78 262.6 5.6 1.7e-78 262.1 3.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBK23294.2 - 1.3e-08 34.2 0.9 2.4e-08 33.3 0.2 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBK23294.2 - 0.00051 20.2 1.1 0.0012 19.1 0.7 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 CBK23294.2 - 0.00094 18.8 1.9 0.028 13.9 0.2 2.8 1 1 2 3 3 3 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.14 CBK23294.2 - 0.0011 18.1 3.6 0.0053 15.8 2.5 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 CBK23294.2 - 0.012 15.5 0.5 0.035 14.1 0.3 1.8 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 CBK23294.2 - 0.02 15.0 1.9 0.052 13.6 1.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CBK23294.2 - 0.029 13.7 0.2 0.049 12.9 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Malic_M PF03949.10 CBK23294.2 - 0.19 11.2 3.5 1.2 8.5 0.1 2.4 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain Pkinase PF00069.20 CBK23295.2 - 3.3e-74 249.3 0.0 4.6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23295.2 - 2.8e-34 118.3 0.0 4.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23295.2 - 6.3e-07 28.6 0.0 4.2e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CBK23295.2 - 1.9e-06 27.0 0.0 6.9e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ste5_C PF12194.3 CBK23295.2 - 0.0013 18.4 0.7 0.0021 17.6 0.5 1.4 1 0 0 1 1 1 1 Protein kinase Fus3-binding Pox_ser-thr_kin PF05445.6 CBK23295.2 - 0.011 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CBK23295.2 - 0.025 14.3 0.0 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBK23295.2 - 0.049 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HGD-D PF06050.8 CBK23295.2 - 0.055 12.2 0.0 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Rtf2 PF04641.7 CBK23296.2 - 1.4e-43 148.9 1.6 1.7e-43 148.6 1.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Mid2 PF04478.7 CBK23297.2 - 0.03 13.7 0.2 0.078 12.3 0.1 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 CBK23297.2 - 0.3 11.5 2.1 1.7 9.0 1.6 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CTP_transf_1 PF01148.15 CBK23298.2 - 6.2e-61 206.3 30.2 1e-60 205.6 20.9 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family Rcd1 PF04078.8 CBK23299.2 - 9.7e-07 27.8 0.4 1.2e-06 27.5 0.3 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Myosin_head PF00063.16 CBK23300.2 - 1.2e-196 654.9 0.1 9.9e-196 651.8 0.1 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) WW PF00397.21 CBK23300.2 - 5e-06 26.2 1.9 5e-06 26.2 1.3 2.0 2 0 0 2 2 2 1 WW domain Myosin_N PF02736.14 CBK23300.2 - 0.005 16.4 1.1 0.005 16.4 0.7 1.8 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain PilM PF07419.7 CBK23300.2 - 0.0088 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 PilM AAA_16 PF13191.1 CBK23300.2 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CBK23300.2 - 0.13 12.4 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPT PF03151.11 CBK23301.2 - 2.4e-20 72.7 11.6 2.4e-20 72.7 8.0 2.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CBK23301.2 - 1.6e-12 46.9 25.7 2.5e-12 46.3 17.8 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBK23301.2 - 5.3e-10 39.4 27.2 5.1e-07 29.7 4.9 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CBK23301.2 - 0.0051 16.9 24.0 0.01 16.0 2.7 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DNA_ligase_A_C PF04679.10 CBK23302.2 - 2.2e-20 72.8 0.0 3.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.16 CBK23302.2 - 1.4e-17 63.7 0.0 2.2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CBK23302.2 - 0.00017 21.1 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 2 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 CBK23302.2 - 0.056 13.1 0.0 1.4 8.5 0.0 2.2 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Cnd1 PF12717.2 CBK23303.2 - 8.7e-30 103.8 2.4 1.2e-29 103.4 1.7 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBK23303.2 - 7.1e-05 21.3 1.3 8.4e-05 21.0 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Nipped-B_C PF12830.2 CBK23303.2 - 0.00014 21.5 0.6 0.0017 18.0 0.5 2.0 1 1 1 2 2 2 2 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 CBK23303.2 - 0.0013 18.9 0.0 0.0033 17.6 0.0 1.7 1 1 0 1 1 1 1 HEAT repeats Cnd3 PF12719.2 CBK23303.2 - 0.0021 17.0 1.4 0.017 14.1 1.0 2.3 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CBK23303.2 - 0.055 13.5 0.5 11 6.4 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Vac14_Fab1_bd PF12755.2 CBK23303.2 - 0.14 12.5 1.7 6.7 7.1 0.1 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Ribosomal_L7Ae PF01248.21 CBK23304.2 - 2.7e-27 94.1 0.1 3.3e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK23304.2 - 0.0009 19.1 0.1 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CBK23304.2 - 0.024 14.3 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF2229 PF09989.4 CBK23304.2 - 0.048 13.1 0.2 0.17 11.2 0.0 1.7 1 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) MFS_1 PF07690.11 CBK23305.2 - 1.9e-08 33.4 16.5 1.9e-08 33.4 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CBK23305.2 - 0.00018 19.7 0.4 0.00026 19.1 0.3 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 CBK23305.2 - 0.0026 16.4 3.9 0.0026 16.4 2.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter ROK PF00480.15 CBK23306.2 - 4.8e-15 55.8 0.1 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 ROK family UPF0180 PF03698.8 CBK23306.2 - 0.034 13.9 0.1 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Dpy-30 PF05186.8 CBK23307.2 - 7e-19 67.0 0.1 9e-19 66.6 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.12 CBK23307.2 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF1950 PF09187.5 CBK23307.2 - 0.054 13.6 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF1950) zf-RING_2 PF13639.1 CBK23308.2 - 3.5e-16 58.7 4.9 5.7e-16 58.0 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBK23308.2 - 8.6e-10 38.4 5.7 1.6e-09 37.5 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23308.2 - 3.5e-09 36.1 5.1 6.6e-09 35.2 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23308.2 - 4.9e-09 35.7 3.6 8.4e-09 35.0 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBK23308.2 - 1.6e-08 34.5 4.4 3.4e-08 33.4 3.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBK23308.2 - 5e-07 29.2 2.9 9.7e-07 28.3 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBK23308.2 - 7.9e-05 22.4 5.1 8.8e-05 22.2 2.4 2.0 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBK23308.2 - 0.00019 21.0 1.7 0.0003 20.4 0.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBK23308.2 - 0.00069 19.4 2.6 0.00069 19.4 1.8 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 CBK23308.2 - 0.0012 18.5 3.9 0.011 15.4 0.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBK23308.2 - 0.0012 18.7 4.8 0.03 14.2 3.4 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain Baculo_RING PF05883.6 CBK23308.2 - 0.0086 15.9 0.6 0.059 13.1 0.3 2.1 1 1 1 2 2 2 1 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.1 CBK23308.2 - 0.0092 15.5 4.7 0.087 12.3 3.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.3 CBK23308.2 - 0.013 14.9 3.2 0.029 13.8 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBK23308.2 - 0.015 15.0 2.4 0.92 9.3 0.4 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBK23308.2 - 0.015 14.8 4.2 0.027 14.0 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YlaC PF10777.4 CBK23308.2 - 0.024 14.1 0.8 0.037 13.5 0.6 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC YdjO PF14169.1 CBK23308.2 - 0.047 13.1 1.5 7.7 6.0 0.3 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO PHD PF00628.24 CBK23308.2 - 0.058 13.0 3.9 0.1 12.2 2.7 1.5 1 0 0 1 1 1 0 PHD-finger Rtf2 PF04641.7 CBK23308.2 - 0.06 12.5 1.0 0.63 9.1 0.5 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger Rad50_zn_hook PF04423.9 CBK23308.2 - 0.072 12.5 0.1 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.2 CBK23308.2 - 0.11 12.5 4.0 0.22 11.5 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain FYVE PF01363.16 CBK23308.2 - 0.2 11.5 3.4 0.73 9.7 2.3 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.15 CBK23308.2 - 0.38 10.2 5.8 1.8 8.1 4.0 2.2 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING-like PF08746.6 CBK23308.2 - 0.4 10.7 4.3 1.6 8.7 3.0 2.0 1 1 1 2 2 2 0 RING-like domain PQ-loop PF04193.9 CBK23309.2 - 9.4e-25 85.9 14.8 5.6e-15 54.6 1.0 3.1 2 1 1 3 3 3 2 PQ loop repeat zf-RING_6 PF14835.1 CBK23310.2 - 1.8e-09 37.2 3.5 1.8e-09 37.2 2.5 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 CBK23310.2 - 2.9e-09 36.7 13.9 4.9e-09 36.0 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK23310.2 - 3.9e-09 36.2 12.8 1.3e-08 34.5 6.5 2.5 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 CBK23310.2 - 4.4e-09 35.6 0.0 7.1e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.1 CBK23310.2 - 3.8e-08 32.8 11.3 4e-08 32.7 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23310.2 - 7.8e-08 31.8 14.6 8.3e-08 31.7 6.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23310.2 - 2.2e-07 30.4 9.9 2.2e-07 30.4 6.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.7 CBK23310.2 - 7.9e-06 25.2 2.0 2.2e-05 23.8 0.5 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger zf-rbx1 PF12678.2 CBK23310.2 - 2.2e-05 24.4 6.1 2.6e-05 24.2 2.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBK23310.2 - 0.00022 20.8 2.4 0.00022 20.8 1.7 2.6 2 1 1 3 3 3 1 RING-type zinc-finger U-box PF04564.10 CBK23310.2 - 0.00029 20.7 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.1 CBK23310.2 - 0.0081 15.7 5.6 0.0081 15.7 3.9 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBK23310.2 - 0.012 15.4 9.8 0.012 15.4 6.8 3.0 3 1 1 4 4 3 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBK23310.2 - 0.021 14.6 3.8 0.025 14.4 1.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Det1 PF09737.4 CBK23310.2 - 0.038 12.7 0.1 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 zf-MIZ PF02891.15 CBK23310.2 - 0.042 13.3 12.9 0.17 11.4 6.6 2.8 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBK23310.2 - 0.16 11.5 8.6 0.067 12.7 3.7 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 CBK23310.2 - 1.4 8.4 6.5 29 4.1 0.5 3.6 3 0 0 3 3 3 0 RecR protein zf-C2H2_4 PF13894.1 CBK23310.2 - 1.7 9.1 10.0 22 5.6 0.1 4.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK23310.2 - 3 8.2 14.3 0.54 10.6 0.4 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 CBK23310.2 - 3.9 7.6 11.7 46 4.2 0.1 3.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.1 CBK23310.2 - 7.1 6.2 11.0 35 4.0 4.1 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.7 CBK23310.2 - 8.3 6.2 9.8 7.4 6.4 3.5 2.9 2 1 1 3 3 3 0 zinc-ribbons CPSase_L_D2 PF02786.12 CBK23311.2 - 2.1e-76 255.9 0.0 4.3e-76 254.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CBK23311.2 - 8.2e-58 195.0 0.0 1.4e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CBK23311.2 - 1.5e-37 128.0 0.1 3.4e-37 126.9 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK23311.2 - 6.1e-30 103.3 0.0 2.1e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CBK23311.2 - 1.8e-27 96.5 0.0 3.3e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 CBK23311.2 - 7e-19 67.7 0.0 1.5e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBK23311.2 - 2e-17 63.5 0.0 5.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CBK23311.2 - 3.3e-17 61.8 3.9 8.8e-17 60.5 2.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBK23311.2 - 6.6e-12 45.2 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CBK23311.2 - 3.1e-10 39.5 0.3 0.00057 19.4 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 CBK23311.2 - 7.9e-08 32.0 0.0 2.6e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 CBK23311.2 - 4.1e-07 29.5 0.0 9.1e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBK23311.2 - 7.9e-07 29.0 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK23311.2 - 2.2e-05 23.9 1.4 0.016 14.5 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 CBK23311.2 - 0.00029 20.1 1.3 0.19 10.8 0.1 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 CBK23311.2 - 0.00053 20.2 0.2 0.4 11.0 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 CBK23311.2 - 0.02 14.0 1.9 0.038 13.1 1.3 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 CBK23311.2 - 0.038 13.6 2.0 0.15 11.7 1.3 2.0 1 1 0 1 1 1 0 Glycine cleavage H-protein LRR_5 PF13306.1 CBK23312.2 - 0.11 12.2 2.9 0.2 11.3 2.0 1.4 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) DEC-1_N PF04625.8 CBK23312.2 - 1.4 7.5 11.3 2.3 6.7 7.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1949 PF09186.6 CBK23314.2 - 0.0064 16.0 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) Lactamase_B_2 PF12706.2 CBK23318.2 - 0.00031 20.3 0.2 0.00075 19.0 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ATG_C PF09333.6 CBK23319.2 - 0.00011 22.3 0.0 0.00051 20.1 0.0 2.1 1 1 0 1 1 1 1 ATG C terminal domain Methyltransf_15 PF09445.5 CBK23320.2 - 1.1e-35 122.6 0.0 1.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 CBK23320.2 - 4.8e-12 45.8 0.0 8.1e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBK23320.2 - 2.9e-09 36.9 0.0 5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBK23320.2 - 5.4e-06 25.9 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 CBK23320.2 - 1.5e-05 25.5 0.0 2.5e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBK23320.2 - 0.00056 19.5 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 CBK23320.2 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DNA_methylase PF00145.12 CBK23320.2 - 0.053 12.6 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase LRR_4 PF12799.2 CBK23321.2 - 1.2e-60 200.2 30.7 2.7e-11 42.8 0.3 6.9 2 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK23321.2 - 3e-25 87.7 24.4 3.6e-10 39.4 1.9 5.8 3 3 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CBK23321.2 - 1.3e-18 64.1 23.3 0.0053 16.5 0.1 10.9 10 1 1 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 CBK23321.2 - 2.1e-17 61.1 14.3 0.48 10.6 0.0 10.6 6 1 5 11 11 11 7 Leucine Rich repeat LRR_7 PF13504.1 CBK23321.2 - 3.9e-15 53.2 18.0 0.14 12.4 0.0 10.6 9 1 1 10 10 10 5 Leucine rich repeat LRR_9 PF14580.1 CBK23321.2 - 1.7e-09 37.4 5.6 0.0084 15.6 1.7 3.7 1 1 2 3 3 3 3 Leucine-rich repeat Myb_DNA-binding PF00249.26 CBK23322.2 - 1.9e-12 46.9 1.8 3.9e-12 46.0 1.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK23322.2 - 3.1e-08 33.6 0.3 3.1e-08 33.6 0.2 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain SAGA-Tad1 PF12767.2 CBK23322.2 - 0.019 14.6 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ER-remodelling PF14755.1 CBK23322.2 - 0.1 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Myb_DNA-bind_4 PF13837.1 CBK23322.2 - 7.2 6.8 6.9 3.2 7.9 1.0 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Prenyltransf PF01255.14 CBK23323.2 - 2.7e-25 88.8 0.0 2.8e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase TMP_2 PF06791.8 CBK23323.2 - 0.088 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein Prenyltransf PF01255.14 CBK23324.2 - 1.1e-29 103.1 0.1 1.3e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AMMECR1 PF01871.12 CBK23325.2 - 3.5e-44 149.9 0.0 4.5e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 RestrictionMunI PF11407.3 CBK23325.2 - 0.015 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction enzyme MunI RabGAP-TBC PF00566.13 CBK23326.2 - 1.5e-14 53.9 0.8 1.9e-14 53.6 0.6 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pox_F16 PF04708.7 CBK23326.2 - 0.053 12.7 0.0 0.2 10.9 0.0 1.9 3 0 0 3 3 3 0 Poxvirus F16 protein DUF566 PF04484.7 CBK23327.2 - 0.29 10.5 3.2 0.35 10.3 2.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aldose_epim PF01263.15 CBK23328.2 - 1.9e-18 66.6 0.1 2.3e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase UPF0449 PF15136.1 CBK23329.2 - 0.0017 18.5 0.1 0.0022 18.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 Med21 PF11221.3 CBK23329.2 - 0.099 12.6 0.8 0.13 12.2 0.5 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF2335 PF10097.4 CBK23329.2 - 0.23 11.0 1.1 0.57 9.8 0.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Ist1 PF03398.9 CBK23330.2 - 1.5e-13 50.4 0.1 1.7e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RRM_2 PF04059.7 CBK23331.2 - 2.7e-28 97.8 0.1 3.6e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 CBK23331.2 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 CBK23331.2 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family RRM_1 PF00076.17 CBK23331.2 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.13 CBK23331.2 - 0.36 10.4 8.8 3.2 7.3 6.1 2.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Coatomer_WDAD PF04053.9 CBK23332.2 - 0.0041 15.9 0.0 0.059 12.1 0.0 2.2 1 1 0 1 1 1 1 Coatomer WD associated region DnaJ PF00226.26 CBK23334.2 - 1.7e-24 85.2 1.0 2.8e-24 84.6 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBK23334.2 - 1.7e-21 75.8 0.0 1e-19 70.2 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBK23334.2 - 1e-12 47.8 17.2 1.8e-12 47.0 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 CBK23334.2 - 0.65 9.5 7.5 1.4 8.4 0.2 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain HypA PF01155.14 CBK23334.2 - 2.2 8.0 10.6 2.2 8.0 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Pro_isomerase PF00160.16 CBK23335.2 - 9.7e-51 172.0 0.0 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NDUFA12 PF05071.11 CBK23336.2 - 1.7e-14 54.1 5.7 1.7e-14 54.1 3.9 1.8 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Defensin_4 PF07936.7 CBK23338.2 - 0.049 13.2 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Potassium-channel blocking toxin Phage_GP20 PF06810.6 CBK23339.2 - 0.009 15.4 6.4 0.009 15.4 4.4 4.5 2 1 2 4 4 4 2 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 CBK23339.2 - 2.1 7.4 30.2 0.91 8.6 2.1 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 CBK23339.2 - 9.3 5.6 72.0 0.067 12.6 13.3 4.2 1 1 2 3 3 3 0 Intermediate filament protein Bromodomain PF00439.20 CBK23340.2 - 5.4e-20 71.1 0.0 1.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain ATP-synt PF00231.14 CBK23340.2 - 0.032 13.5 0.0 0.054 12.8 0.0 1.4 2 0 0 2 2 2 0 ATP synthase PRMT5 PF05185.11 CBK23341.2 - 3.8e-10 39.2 0.2 4.8e-10 38.9 0.2 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 CBK23341.2 - 5.8e-10 38.9 0.1 8.4e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK23341.2 - 8.6e-10 39.1 0.0 6.6e-09 36.3 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK23341.2 - 3.1e-08 33.6 0.0 5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK23341.2 - 6.3e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBK23341.2 - 3.1e-07 29.8 0.0 4.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CBK23341.2 - 2.9e-05 23.8 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK23341.2 - 8.9e-05 21.9 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CBK23341.2 - 0.00015 20.5 0.1 0.00025 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CBK23341.2 - 0.00081 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBK23341.2 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK23341.2 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBK23341.2 - 0.0018 19.0 0.0 0.0038 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CBK23341.2 - 0.0038 16.2 0.3 0.029 13.4 0.2 2.1 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 CBK23341.2 - 0.0046 16.5 0.1 0.0074 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CBK23341.2 - 0.013 14.9 0.1 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Herpes_UL49_2 PF04823.7 CBK23341.2 - 0.054 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Cons_hypoth95 PF03602.10 CBK23341.2 - 0.13 11.6 0.0 0.31 10.3 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical protein 95 zf-DHHC PF01529.15 CBK23342.2 - 3.3e-40 137.3 11.4 4.8e-40 136.7 7.9 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 CBK23342.2 - 0.086 12.8 1.2 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Transglut_core3 PF13471.1 CBK23342.2 - 0.13 12.0 0.2 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily Metallophos_2 PF12850.2 CBK23344.2 - 3.8e-05 23.5 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CBK23344.2 - 0.00016 21.1 6.4 0.0023 17.3 4.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Calreticulin PF00262.13 CBK23345.2 - 4e-127 423.8 0.0 5.4e-127 423.4 0.0 1.2 1 0 0 1 1 1 1 Calreticulin family E1-E2_ATPase PF00122.15 CBK23346.2 - 2e-23 82.6 0.0 3.7e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBK23346.2 - 2.4e-12 47.7 0.0 2.5e-10 41.1 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK23346.2 - 4.3e-12 46.5 0.0 1.6e-11 44.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK23346.2 - 2.3e-07 30.6 0.0 1.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK23346.2 - 2.9e-05 23.7 0.4 0.006 16.1 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Citrus_P18 PF05520.6 CBK23346.2 - 0.032 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Herpes_U47 PF05467.6 CBK23346.2 - 0.09 10.6 0.1 0.14 9.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 RRM_5 PF13893.1 CBK23347.2 - 3.3e-15 55.6 0.0 3.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK23347.2 - 6.1e-10 38.5 0.0 0.00037 20.0 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23347.2 - 1.1e-09 38.1 0.0 5.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBK23347.2 - 1.5e-05 24.7 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 CBK23347.2 - 0.0098 15.4 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 CBK23347.2 - 0.039 13.6 0.0 0.31 10.7 0.0 2.4 3 0 0 3 3 3 0 Limkain b1 DUF106 PF01956.11 CBK23347.2 - 0.043 13.3 0.4 0.069 12.6 0.3 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 LSM PF01423.17 CBK23348.2 - 4.8e-09 35.6 0.0 5.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SHMT PF00464.14 CBK23349.2 - 5e-181 601.3 0.0 5.9e-181 601.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBK23349.2 - 0.0062 15.7 0.1 0.025 13.7 0.1 1.8 1 1 1 2 2 2 1 Beta-eliminating lyase Macro PF01661.16 CBK23349.2 - 0.036 13.9 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Macro domain Ribosomal_S3_C PF00189.15 CBK23350.2 - 1.2e-15 57.4 0.2 2e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBK23350.2 - 2.3e-11 43.1 0.2 4.1e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CBK23350.2 - 0.0099 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.15 CBK23351.2 - 1.5e-07 29.7 0.0 1.5e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein NT-C2 PF10358.4 CBK23351.2 - 0.033 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins B56 PF01603.15 CBK23352.2 - 2.2e-90 303.2 1.4 5.2e-90 301.9 0.9 1.6 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) AAA_12 PF13087.1 CBK23352.2 - 2.7e-29 101.9 0.0 5.7e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK23352.2 - 6.6e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK23352.2 - 3.8e-10 39.3 0.0 1.2e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBK23352.2 - 0.00015 21.4 0.0 0.013 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBK23352.2 - 0.00046 19.6 0.0 0.00099 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CBK23352.2 - 0.0015 18.0 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 CBK23352.2 - 0.0024 18.0 0.0 0.007 16.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CBK23352.2 - 0.0037 17.4 0.0 0.033 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CBK23352.2 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 CBK23352.2 - 0.011 15.8 0.0 0.093 12.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CBK23352.2 - 0.034 13.9 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CBK23352.2 - 0.038 13.9 1.1 0.54 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 CBK23352.2 - 0.045 12.7 0.0 0.11 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CBK23352.2 - 0.092 13.5 1.0 1.1 10.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain RhoGAP PF00620.22 CBK23353.2 - 4e-13 49.2 0.0 6.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 CBK23353.2 - 8.4e-11 42.2 0.1 1.7e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1336 PF07059.7 CBK23354.2 - 6.7e-13 48.5 0.0 7.9e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Nucleotid_trans PF03407.11 CBK23355.2 - 2.2e-22 79.8 2.5 2.2e-22 79.8 1.8 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 CBK23355.2 - 0.039 13.2 0.6 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Mannosyltransferase putative Glyco_transf_49 PF13896.1 CBK23359.2 - 1.3e-10 40.9 4.0 6.8e-07 28.6 0.3 2.7 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK23359.2 - 0.0021 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UPF0223 PF05256.7 CBK23359.2 - 0.076 13.1 0.3 0.63 10.1 0.2 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) Ku_PK_bind PF08785.6 CBK23360.2 - 0.0099 15.7 0.3 0.014 15.3 0.2 1.2 1 0 0 1 1 1 1 Ku C terminal domain like Ribosomal_L7Ae PF01248.21 CBK23362.2 - 2.9e-21 74.7 0.6 5e-21 74.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK23362.2 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Glyco_transf_49 PF13896.1 CBK23363.2 - 1.4e-11 44.0 1.7 4e-07 29.4 0.4 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK23363.2 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ku_PK_bind PF08785.6 CBK23365.2 - 0.057 13.3 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Ku C terminal domain like Glyco_transf_49 PF13896.1 CBK23366.2 - 3.3e-09 36.2 3.5 2.7e-07 30.0 0.1 2.5 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK23366.2 - 0.00052 19.7 0.5 0.0013 18.4 0.2 1.7 1 1 0 1 1 1 1 F-box associated Ribosomal_L7Ae PF01248.21 CBK23367.2 - 3.8e-21 74.3 0.6 6.6e-21 73.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Surface_Ag_2 PF01617.12 CBK23368.2 - 0.056 12.6 0.1 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Surface antigen Ank_2 PF12796.2 CBK23369.2 - 1.7e-14 53.9 0.1 5.7e-12 45.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBK23369.2 - 2.2e-10 40.7 0.1 1.7e-07 31.5 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 CBK23369.2 - 2.1e-07 30.4 0.2 0.072 12.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CBK23369.2 - 1.6e-06 27.8 0.2 9.9 6.7 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 CBK23369.2 - 8.1e-05 22.7 0.2 0.7 10.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MoeZ_MoeB PF05237.8 CBK23369.2 - 0.0026 17.3 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 MoeZ/MoeB domain Alpha_E3_glycop PF01563.11 CBK23369.2 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein U1snRNP70_N PF12220.3 CBK23369.2 - 0.28 11.5 6.9 0.58 10.5 0.1 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Fer2_3 PF13085.1 CBK23370.2 - 2.3e-32 111.1 0.0 3.8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK23370.2 - 7.2e-10 39.0 6.7 7.2e-10 39.0 4.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK23370.2 - 2.7e-09 36.8 4.9 2.7e-09 36.8 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK23370.2 - 6.2e-06 26.5 9.1 8.5e-06 26.1 2.1 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK23370.2 - 0.00056 19.6 4.8 0.00056 19.6 3.3 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK23370.2 - 0.0014 18.8 10.4 0.01 16.0 5.6 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CBK23370.2 - 0.009 15.7 0.5 0.009 15.7 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 CBK23370.2 - 0.018 15.4 7.6 0.018 15.4 5.3 2.5 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBK23370.2 - 0.059 13.9 1.1 1.6 9.3 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 CBK23370.2 - 1.1 9.2 16.7 0.35 10.8 3.3 3.8 4 0 0 4 4 4 0 4Fe-4S binding domain Ribosomal_L44 PF00935.14 CBK23371.2 - 2.2e-32 110.8 12.2 2.2e-32 110.8 8.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 CBK23371.2 - 0.045 14.0 4.1 0.045 14.0 2.8 2.8 2 1 0 2 2 2 0 Ribosomal protein L33 DUF1272 PF06906.6 CBK23371.2 - 0.23 11.3 3.3 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UBR PF02207.15 CBK23371.2 - 0.4 10.4 5.1 0.6 9.8 0.7 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) NOB1_Zn_bind PF08772.6 CBK23371.2 - 1.6 8.6 8.3 0.084 12.7 1.2 2.0 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.11 CBK23371.2 - 3.8 7.4 9.0 12 5.9 6.2 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-DNL PF05180.7 CBK23371.2 - 5.1 6.8 6.8 14 5.5 0.7 2.3 2 0 0 2 2 2 0 DNL zinc finger Tnp_zf-ribbon_2 PF13842.1 CBK23371.2 - 8.3 6.9 14.0 1.6 9.2 0.8 2.7 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Ribosomal_L37ae PF01780.14 CBK23372.2 - 1.9e-38 130.2 9.8 2.2e-38 130.0 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 CBK23372.2 - 0.019 14.3 4.7 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4518 PF15008.1 CBK23372.2 - 0.039 12.9 0.3 0.048 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) zf-BED PF02892.10 CBK23372.2 - 0.05 13.3 0.5 0.05 13.3 0.3 2.7 1 1 2 3 3 3 0 BED zinc finger Zn-ribbon_8 PF09723.5 CBK23372.2 - 0.23 11.4 2.3 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBK23372.2 - 0.27 11.0 8.2 0.57 10.0 5.7 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain CarbpepA_inh PF02977.10 CBK23372.2 - 5.3 6.6 8.6 6.4 6.4 2.6 2.7 2 1 1 3 3 3 0 Carboxypeptidase A inhibitor Frataxin_Cyay PF01491.11 CBK23374.2 - 5.3e-27 93.7 0.3 9e-27 93.0 0.2 1.4 1 1 0 1 1 1 1 Frataxin-like domain TCTP PF00838.12 CBK23375.2 - 5.6e-24 85.0 11.7 7.4e-20 71.5 8.1 3.1 1 1 0 1 1 1 1 Translationally controlled tumour protein UvrD_C PF13361.1 CBK23375.2 - 0.0079 15.7 1.4 0.0093 15.4 1.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Polysacc_synt_4 PF04669.8 CBK23375.2 - 0.015 14.7 0.6 0.022 14.1 0.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis DUF4239 PF14023.1 CBK23375.2 - 0.036 13.4 0.5 0.055 12.8 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) ISG65-75 PF11727.3 CBK23375.2 - 0.075 12.0 3.5 0.058 12.4 0.8 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein Interferon PF00143.14 CBK23375.2 - 0.11 12.3 1.0 0.18 11.6 0.4 1.6 1 1 0 1 1 1 0 Interferon alpha/beta domain PPR PF01535.15 CBK23375.2 - 5.2 7.2 6.0 49 4.2 0.1 3.6 4 0 0 4 4 4 0 PPR repeat Pkinase PF00069.20 CBK23376.2 - 1.3e-53 181.8 0.0 1.9e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23376.2 - 5.8e-28 97.6 0.0 9.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CBK23376.2 - 2.9e-20 72.0 0.0 1.1e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CBK23376.2 - 1.3e-08 34.1 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBK23376.2 - 0.0031 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 CBK23377.2 - 0.0001 21.5 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GP40 PF11025.3 CBK23378.2 - 0.26 10.8 1.5 0.32 10.5 1.0 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Galactosyl_T PF01762.16 CBK23380.2 - 2.6e-33 115.2 0.0 4.3e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Baculo_gp41 PF04700.7 CBK23380.2 - 0.011 15.1 0.3 0.026 13.9 0.2 1.6 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Thioredoxin PF00085.15 CBK23382.2 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Ctr PF04145.10 CBK23382.2 - 0.11 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Thioredoxin PF00085.15 CBK23383.2 - 1.5e-15 56.7 0.1 1.1e-10 41.0 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBK23383.2 - 6.9e-07 29.2 2.5 5.1e-05 23.1 0.4 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBK23383.2 - 0.061 13.5 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CBK23383.2 - 0.11 12.2 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Sas10 PF09368.5 CBK23384.2 - 4e-25 87.7 5.6 4e-25 87.7 3.9 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CBK23384.2 - 0.00073 19.6 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ebola_NP PF05505.7 CBK23384.2 - 0.9 7.5 11.2 1.4 6.8 7.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein SH3_9 PF14604.1 CBK23385.2 - 2.8e-16 58.8 0.1 6.1e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBK23385.2 - 6.6e-15 54.2 0.1 1.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBK23385.2 - 7.9e-13 47.6 0.0 1.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 CBK23385.2 - 1.3e-08 34.6 9.4 2.2e-08 33.8 6.5 1.4 1 1 0 1 1 1 1 BAR domain TPR_MLP1_2 PF07926.7 CBK23385.2 - 0.096 12.4 4.7 0.56 9.9 3.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PUF PF00806.14 CBK23386.2 - 1.8e-19 68.0 3.4 1.1e-05 24.6 0.2 5.3 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF445 PF04286.7 CBK23386.2 - 0.28 10.6 0.1 0.38 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TFIIA PF03153.8 CBK23386.2 - 0.99 9.2 19.0 1.5 8.6 13.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-5_eIF-2B PF01873.12 CBK23387.2 - 4.6e-34 116.7 0.6 5.4e-34 116.5 0.4 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 CBK23387.2 - 0.0024 18.1 0.9 0.027 14.7 0.7 2.1 1 1 1 2 2 2 2 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 CBK23387.2 - 0.026 13.8 0.3 0.041 13.1 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 CBK23387.2 - 0.39 10.2 2.9 3 7.3 2.0 2.3 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 CBK23387.2 - 1.2 9.3 5.5 1.1 9.5 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain zinc_ribbon_6 PF14599.1 CBK23387.2 - 2.1 8.1 7.4 3 7.6 2.0 2.6 2 1 1 3 3 3 0 Zinc-ribbon DUF1682 PF07946.9 CBK23388.2 - 8.5e-33 113.5 0.0 1.7e-32 112.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4090 PF13319.1 CBK23389.2 - 0.0087 15.9 1.0 0.01 15.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) IATP PF04568.7 CBK23389.2 - 0.019 15.0 5.3 0.026 14.5 3.6 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4432 PF14486.1 CBK23389.2 - 0.046 12.2 0.0 0.049 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) DUF4460 PF14687.1 CBK23389.2 - 0.075 12.7 1.2 0.12 12.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) ACBP PF00887.14 CBK23390.2 - 1.7e-29 101.3 0.4 1.8e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein GTP_EFTU PF00009.22 CBK23391.2 - 1.2e-50 171.5 0.0 1.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBK23392.2 - 1.2e-15 57.1 0.0 3.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBK23392.2 - 7.2e-10 38.5 0.0 1.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBK23392.2 - 3.5e-05 23.3 0.0 0.0002 20.8 0.0 2.2 3 0 0 3 3 3 1 Elongation factor G, domain IV SRP-alpha_N PF04086.8 CBK23392.2 - 0.0043 16.4 7.9 0.0043 16.4 5.5 1.6 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal Pex14_N PF04695.8 CBK23392.2 - 1.9 8.5 16.3 0.47 10.5 7.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CBK23392.2 - 5.5 4.5 19.1 3.3 5.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Lin-8 PF03353.10 CBK23392.2 - 6.2 6.0 15.0 11 5.2 10.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Kei1 PF08552.6 CBK23392.2 - 7.5 6.1 5.7 7.4 6.1 2.8 1.8 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 WD40 PF00400.27 CBK23394.2 - 5.6e-19 67.2 17.3 3.2e-10 39.4 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat FeThRed_B PF02943.10 CBK23394.2 - 0.082 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain zf-C2HC5 PF06221.8 CBK23395.2 - 2.4e-11 43.1 7.8 3.8e-11 42.5 5.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TerY-C PF15616.1 CBK23395.2 - 0.01 15.7 4.2 0.026 14.4 2.9 1.7 1 0 0 1 1 1 1 TerY-C metal binding domain DUF3275 PF11679.3 CBK23395.2 - 0.091 12.3 1.0 0.16 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) zf-ribbon_3 PF13248.1 CBK23395.2 - 0.3 10.3 4.5 0.59 9.4 3.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Pol_alpha_B_N PF08418.5 CBK23395.2 - 0.71 9.3 6.9 0.29 10.6 2.0 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal TAF PF02969.12 CBK23396.2 - 6.7e-05 22.7 0.2 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CBK23396.2 - 0.012 15.6 0.3 0.024 14.7 0.2 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 ProRS-C_1 PF09180.6 CBK23397.2 - 7.7e-22 76.9 3.2 1.2e-21 76.3 1.6 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CBK23397.2 - 3.1e-19 69.1 0.1 5.1e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK23397.2 - 5.2e-15 55.1 0.3 1.6e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain DUF92 PF01940.11 CBK23398.2 - 2.6e-18 66.0 0.0 4.5e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Integral membrane protein DUF92 UMPH-1 PF05822.7 CBK23400.2 - 1.7e-72 243.7 0.6 2.1e-72 243.4 0.4 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.2 CBK23400.2 - 0.011 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK23400.2 - 0.13 12.4 0.1 6.3 6.9 0.0 2.9 1 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 CBK23401.2 - 1.8e-17 62.7 0.0 3.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23401.2 - 2.4e-15 56.2 0.0 3.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23401.2 - 4.3e-14 52.0 0.0 6.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK23401.2 - 0.0037 16.9 0.1 0.007 16.0 0.1 1.4 1 0 0 1 1 1 1 Limkain b1 DUF566 PF04484.7 CBK23401.2 - 9 5.7 35.6 0.02 14.4 6.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) Pkinase PF00069.20 CBK23402.2 - 1.2e-74 250.7 0.0 1.4e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23402.2 - 8.4e-38 129.9 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23402.2 - 8.3e-05 21.6 0.0 0.0003 19.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 CBK23402.2 - 0.0069 16.8 0.4 0.013 15.9 0.3 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain zf-DHHC PF01529.15 CBK23403.2 - 3.5e-30 104.6 11.9 3.5e-30 104.6 8.3 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.2 CBK23403.2 - 9.2e-13 48.3 0.1 1.9e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBK23403.2 - 3.5e-12 45.4 0.8 4.6e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBK23403.2 - 1.1e-10 41.6 0.2 2.2e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBK23403.2 - 5.6e-09 35.9 0.2 0.0022 18.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK23403.2 - 8.5e-07 28.6 0.4 0.097 12.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Baculo_11_kDa PF06143.6 CBK23403.2 - 0.031 13.6 3.8 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ribosomal_L40e PF01020.12 CBK23403.2 - 1.5 8.4 8.1 3.6 7.2 5.6 1.6 1 0 0 1 1 1 0 Ribosomal L40e family DUF4131 PF13567.1 CBK23403.2 - 9 5.6 10.9 0.44 9.9 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 CBK23404.2 - 6.6e-19 67.3 0.4 2e-11 43.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23404.2 - 1.1e-15 57.3 0.0 1.3e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23404.2 - 1.6e-05 24.6 0.1 0.079 12.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.10 CBK23404.2 - 1.2 7.7 11.9 0.085 11.4 2.7 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Beach PF02138.13 CBK23405.2 - 9.9e-92 307.1 0.0 1.3e-91 306.8 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CBK23405.2 - 4.2e-06 26.4 0.9 0.012 15.5 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1748 PF08520.5 CBK23407.2 - 9e-08 31.6 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2560 PF10834.3 CBK23408.2 - 0.095 12.6 2.9 0.38 10.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) DUF948 PF06103.6 CBK23408.2 - 0.29 10.9 6.3 0.3 10.9 1.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MRF_C1 PF13887.1 CBK23408.2 - 0.37 9.8 3.1 7 5.7 0.1 2.5 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Spore_coat_CotO PF14153.1 CBK23408.2 - 4 6.8 33.3 2.5 7.5 10.1 2.1 1 1 1 2 2 2 0 Spore coat protein CotO DUF3508 PF12018.3 CBK23408.2 - 8.3 5.3 11.4 7.9 5.3 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Lebercilin PF15619.1 CBK23409.2 - 0.0031 16.9 21.4 0.14 11.5 0.5 3.0 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.1 CBK23409.2 - 0.0081 15.6 16.3 0.33 10.3 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4201) DUF972 PF06156.8 CBK23409.2 - 0.022 15.1 17.9 2 8.7 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF934 PF06073.7 CBK23409.2 - 0.031 13.9 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) Atg14 PF10186.4 CBK23409.2 - 0.045 12.6 19.5 0.061 12.2 13.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_31 PF13847.1 CBK23409.2 - 0.056 13.0 0.3 0.1 12.1 0.1 1.5 2 0 0 2 2 2 0 Methyltransferase domain IncA PF04156.9 CBK23409.2 - 0.2 11.2 33.9 0.28 10.7 17.2 2.1 1 1 1 2 2 2 0 IncA protein Pox_A12 PF04651.8 CBK23409.2 - 0.23 11.5 3.4 0.37 10.9 2.4 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Myosin_tail_1 PF01576.14 CBK23409.2 - 0.36 8.4 24.8 0.7 7.5 6.7 2.1 1 1 1 2 2 2 0 Myosin tail Tnp_P_element PF12017.3 CBK23409.2 - 0.62 9.2 10.9 0.43 9.7 2.2 2.3 1 1 1 2 2 2 0 Transposase protein DUF4404 PF14357.1 CBK23409.2 - 0.75 10.2 14.2 0.23 11.9 2.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Mnd1 PF03962.10 CBK23409.2 - 0.87 9.2 20.0 1 8.9 3.6 2.3 1 1 1 2 2 2 0 Mnd1 family Fib_alpha PF08702.5 CBK23409.2 - 1.2 9.2 15.9 1.6 8.8 4.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RTBV_P46 PF06216.6 CBK23409.2 - 1.4 7.6 6.5 0.19 10.5 1.7 1.5 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Presenilin PF01080.12 CBK23409.2 - 1.7 7.4 4.5 2.1 7.0 3.1 1.1 1 0 0 1 1 1 0 Presenilin Spc7 PF08317.6 CBK23409.2 - 2 6.9 20.6 0.75 8.3 10.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein SPT16 PF08644.6 CBK23409.2 - 2.2 8.1 6.2 0.56 10.0 2.1 1.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Uso1_p115_C PF04871.8 CBK23409.2 - 5.1 7.0 21.3 1.4 8.8 2.0 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region GrpE PF01025.14 CBK23409.2 - 5.3 6.5 13.7 1.4 8.4 0.4 2.8 1 1 1 2 2 2 0 GrpE BLOC1_2 PF10046.4 CBK23409.2 - 6.3 7.0 12.3 12 6.0 1.9 3.2 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.8 CBK23409.2 - 6.5 6.2 13.8 7.7 5.9 7.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Mod_r PF07200.8 CBK23409.2 - 6.9 6.5 23.1 3.1 7.6 1.8 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 CBK23409.2 - 7.6 6.0 21.0 5.4 6.5 1.1 3.9 1 1 4 5 5 5 0 Septum formation initiator DUF342 PF03961.8 CBK23409.2 - 7.8 4.7 12.5 1.2 7.4 3.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ATG16 PF08614.6 CBK23409.2 - 9.6 5.9 25.9 4.9 6.9 0.7 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) E1_dh PF00676.15 CBK23410.2 - 4.2e-92 308.0 0.2 5.5e-92 307.6 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CBK23410.2 - 4.8e-05 22.3 0.0 6.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CBK23410.2 - 0.064 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Sec66 PF09802.4 CBK23410.2 - 0.12 11.7 0.1 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 RdgC PF04381.7 CBK23411.2 - 0.0054 15.7 0.2 0.0063 15.5 0.1 1.2 1 0 0 1 1 1 1 Putative exonuclease, RdgC DUF843 PF05814.6 CBK23411.2 - 0.06 13.1 0.4 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) MyTH4 PF00784.12 CBK23411.2 - 0.088 12.7 1.6 0.12 12.3 1.1 1.2 1 0 0 1 1 1 0 MyTH4 domain DUF2762 PF10960.3 CBK23411.2 - 0.96 9.2 3.7 3.6 7.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) Metallophos PF00149.23 CBK23412.2 - 2.8e-23 82.3 0.0 4.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3801 PF12687.2 CBK23412.2 - 0.00023 20.8 1.8 0.0003 20.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) FimP PF09766.4 CBK23412.2 - 0.43 9.5 15.1 0.59 9.1 10.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CBK23412.2 - 1.1 8.9 12.3 1.7 8.3 8.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CBK23412.2 - 2.3 7.5 11.7 0.31 10.3 5.5 1.5 2 0 0 2 2 2 0 Spt20 family Serinc PF03348.10 CBK23412.2 - 5.9 5.4 8.1 3.6 6.1 3.4 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) KAT11 PF08214.6 CBK23413.2 - 1.6e-34 119.5 0.0 1.1e-33 116.7 0.0 2.0 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.20 CBK23413.2 - 1.5e-18 66.4 0.0 3.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 CBK23413.2 - 0.0083 15.8 7.4 0.0083 15.8 5.1 3.4 3 0 0 3 3 3 1 PHD-finger Utp14 PF04615.8 CBK23415.2 - 5.7e-67 226.4 58.5 1.8e-47 162.0 24.2 2.5 2 1 0 2 2 2 2 Utp14 protein Rotamase PF00639.16 CBK23415.2 - 1.4 9.6 9.2 0.98 10.2 2.9 3.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Peptidase_M18 PF02127.10 CBK23416.2 - 2e-130 435.1 0.0 2.4e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBK23416.2 - 3.7e-05 22.6 0.0 6.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase He_PIG PF05345.7 CBK23418.2 - 1.2e-06 28.3 4.6 0.0003 20.7 0.3 3.0 2 0 0 2 2 2 2 Putative Ig domain Rifin_STEVOR PF02009.11 CBK23418.2 - 0.0034 17.0 1.0 0.0071 16.0 0.7 1.4 1 0 0 1 1 1 1 Rifin/stevor family ASFV_J13L PF05568.6 CBK23418.2 - 0.011 15.2 0.5 0.011 15.2 0.4 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein TMEM154 PF15102.1 CBK23418.2 - 0.014 15.0 0.1 0.056 13.1 0.1 2.0 1 0 0 1 1 1 0 TMEM154 protein family P12 PF12669.2 CBK23418.2 - 0.22 11.7 3.3 0.5 10.6 2.3 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family EphA2_TM PF14575.1 CBK23418.2 - 0.24 11.8 2.5 0.54 10.6 1.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OSTbeta PF15048.1 CBK23418.2 - 0.43 10.6 1.5 0.8 9.7 1.1 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Baculo_11_kDa PF06143.6 CBK23418.2 - 0.52 9.6 3.3 1.1 8.6 2.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ribosomal_L7Ae PF01248.21 CBK23419.2 - 3e-21 74.7 0.6 5e-21 74.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK23419.2 - 0.072 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 KH_1 PF00013.24 CBK23420.2 - 2.3e-31 107.2 0.0 5.4e-06 25.9 0.0 7.3 8 0 0 8 8 8 6 KH domain KH_3 PF13014.1 CBK23420.2 - 4.4e-21 74.0 7.5 2.6e-05 23.7 0.0 6.4 7 0 0 7 7 7 4 KH domain SLS PF14611.1 CBK23420.2 - 3e-11 43.1 0.9 0.001 18.5 0.4 4.3 3 2 1 4 4 4 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CBK23420.2 - 0.03 13.8 4.8 13 5.3 0.2 5.3 6 0 0 6 6 6 0 KH domain PNMA PF14893.1 CBK23420.2 - 0.07 12.1 0.1 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 PNMA EF-hand_7 PF13499.1 CBK23421.2 - 8.3e-08 32.2 0.5 0.00014 21.8 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBK23421.2 - 1.8e-06 27.3 0.8 0.0073 16.0 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBK23421.2 - 9.6e-05 21.9 2.3 0.038 13.6 0.2 3.0 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBK23421.2 - 0.0011 18.8 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBK23421.2 - 0.007 15.5 3.3 0.72 9.3 0.1 3.6 4 0 0 4 4 4 1 EF hand SR-25 PF10500.4 CBK23422.2 - 0.16 11.4 10.1 0.2 11.1 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CBK23422.2 - 0.79 9.7 12.8 1.3 9.1 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ArfGap PF01412.13 CBK23423.2 - 2.7e-19 69.0 1.4 7.3e-19 67.6 0.9 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Daxx PF03344.10 CBK23423.2 - 0.23 9.8 12.3 0.29 9.5 8.5 1.1 1 0 0 1 1 1 0 Daxx Family TB2_DP1_HVA22 PF03134.14 CBK23424.2 - 0.0031 17.2 3.4 0.0031 17.2 2.4 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Spore_YhaL PF14147.1 CBK23424.2 - 0.1 12.0 0.7 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL Col_cuticle_N PF01484.12 CBK23424.2 - 0.11 12.2 0.0 0.11 12.2 0.0 2.3 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Abi PF02517.11 CBK23424.2 - 1.1 9.4 7.9 1.3e+02 2.7 5.5 2.2 1 1 0 1 1 1 0 CAAX protease self-immunity SdpI PF13630.1 CBK23424.2 - 1.1 8.9 4.7 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF4181 PF13789.1 CBK23424.2 - 7.9 6.4 12.9 5.7 6.9 3.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) UAA PF08449.6 CBK23425.2 - 6.2e-50 169.8 11.6 7.3e-50 169.5 8.1 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBK23425.2 - 2.3e-06 27.6 8.0 6.5e-06 26.2 0.6 2.4 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CBK23425.2 - 3.3e-06 26.8 8.7 2.4e-05 24.0 2.4 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBK23425.2 - 0.00021 21.4 9.0 0.036 14.2 0.2 2.5 3 0 0 3 3 3 2 Multidrug resistance efflux transporter IL32 PF15225.1 CBK23425.2 - 0.037 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 Interleukin 32 Acyltransferase PF01553.16 CBK23426.2 - 3.4e-07 29.7 0.0 9.5e-07 28.3 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase DUF2029 PF09594.5 CBK23426.2 - 0.0043 16.5 0.1 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) Cas_TM1802 PF09484.5 CBK23426.2 - 0.095 11.1 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) CcmH PF03918.9 CBK23426.2 - 0.099 11.6 0.2 0.48 9.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein G-patch PF01585.18 CBK23427.2 - 7.7e-15 54.4 1.8 1.2e-14 53.7 1.2 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK23427.2 - 2.5e-06 27.2 1.1 2.5e-06 27.2 0.8 1.8 2 1 0 2 2 2 1 DExH-box splicing factor binding site DUF4561 PF15120.1 CBK23427.2 - 0.099 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) RhoGEF PF00621.15 CBK23428.2 - 1.3e-24 87.1 0.7 1.9e-24 86.4 0.5 1.2 1 0 0 1 1 1 1 RhoGEF domain Ribosomal_L37ae PF01780.14 CBK23429.2 - 2e-25 88.4 3.9 2.2e-25 88.3 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.10 CBK23429.2 - 0.0037 17.0 4.3 0.033 13.9 0.2 2.3 1 1 1 2 2 2 1 BED zinc finger A2L_zn_ribbon PF08792.5 CBK23429.2 - 0.0071 15.7 4.7 0.1 12.0 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain DUF4518 PF15008.1 CBK23429.2 - 0.033 13.2 0.3 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) zf-Sec23_Sec24 PF04810.10 CBK23429.2 - 0.081 12.5 1.1 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 CBK23429.2 - 0.16 11.9 2.7 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBK23429.2 - 0.22 11.3 8.4 0.6 9.9 5.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CBK23429.2 - 0.41 10.3 3.3 0.52 10.0 2.3 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.6 CBK23429.2 - 0.51 10.0 2.8 0.67 9.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Rep_fac-A_C PF08646.5 CBK23429.2 - 1.2 8.8 5.4 13 5.5 3.7 2.0 1 1 0 1 1 1 0 Replication factor-A C terminal domain CarbpepA_inh PF02977.10 CBK23429.2 - 1.5 8.4 6.5 0.5 9.9 0.9 2.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2_6 PF13912.1 CBK23429.2 - 2.2 8.2 5.0 7 6.7 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBK23429.2 - 7.2 7.1 7.6 25 5.4 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBK23429.2 - 7.6 7.0 9.1 5.3 7.5 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger double domain UCH PF00443.24 CBK23430.2 - 9.8e-26 90.4 0.0 2.1e-25 89.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBK23430.2 - 1.2e-11 44.5 2.1 2.3e-11 43.6 1.4 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein IPK PF03770.11 CBK23431.2 - 4.1e-35 121.2 0.0 1.5e-34 119.3 0.0 1.8 1 1 0 1 1 1 1 Inositol polyphosphate kinase TIP49 PF06068.8 CBK23432.2 - 7.4e-181 601.1 1.2 8.9e-181 600.9 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CBK23432.2 - 1.1e-11 45.0 0.1 2.7e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBK23432.2 - 1.9e-08 33.6 3.5 3.5e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK23432.2 - 1.5e-06 28.4 0.1 0.073 13.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK23432.2 - 5.3e-06 26.5 0.0 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CBK23432.2 - 3.6e-05 23.5 0.0 0.0082 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBK23432.2 - 0.00015 21.2 0.3 0.00067 19.1 0.1 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBK23432.2 - 0.00015 21.4 0.0 0.00037 20.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CBK23432.2 - 0.00017 20.8 0.3 0.0041 16.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBK23432.2 - 0.0022 17.5 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 CBK23432.2 - 0.0029 17.0 0.1 0.0077 15.6 0.1 1.7 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CBK23432.2 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK23432.2 - 0.0068 17.2 0.0 0.025 15.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBK23432.2 - 0.0086 15.9 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK23432.2 - 0.013 15.8 0.0 0.09 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBK23432.2 - 0.015 14.3 0.1 0.035 13.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 CBK23432.2 - 0.036 13.6 0.1 0.057 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CBK23432.2 - 0.061 12.5 0.1 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 CBK23432.2 - 0.064 12.2 0.0 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 CBK23432.2 - 0.066 12.1 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Sigma54_activ_2 PF14532.1 CBK23432.2 - 0.09 12.8 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CBK23432.2 - 0.096 12.9 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DnaB_C PF03796.10 CBK23432.2 - 0.097 11.5 0.1 0.31 9.8 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RRS1 PF04939.7 CBK23433.2 - 8.6e-36 122.8 2.0 1e-35 122.6 1.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U1snRNP70_N PF12220.3 CBK23433.2 - 0.095 13.0 0.9 0.12 12.6 0.6 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_L29e PF01779.12 CBK23433.2 - 0.13 12.1 0.7 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Ribosomal L29e protein family DUF4088 PF13317.1 CBK23434.2 - 0.056 12.7 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Nrap PF03813.9 CBK23435.2 - 5.1e-62 209.7 0.0 5.6e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein ESCRT-II PF05871.7 CBK23436.2 - 0.02 14.8 0.2 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit zf-TAZ PF02135.11 CBK23437.2 - 8.4e-10 38.5 10.0 1.9e-09 37.3 7.0 1.6 1 0 0 1 1 1 1 TAZ zinc finger zf-CW PF07496.10 CBK23437.2 - 1.7e-07 30.8 0.8 4.3e-07 29.5 0.6 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger ARID PF01388.16 CBK23437.2 - 7.3e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MFS_1 PF07690.11 CBK23438.2 - 3e-30 105.1 25.8 1.7e-29 102.6 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIIIAH PF12685.2 CBK23438.2 - 0.00096 18.6 1.7 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 SpoIIIAH-like protein Peptidase_S49_N PF08496.5 CBK23438.2 - 0.0085 15.8 2.1 0.16 11.7 0.0 2.9 3 0 0 3 3 3 1 Peptidase family S49 N-terminal OSTbeta PF15048.1 CBK23438.2 - 0.0085 16.1 0.2 0.0085 16.1 0.1 2.7 2 1 0 3 3 3 1 Organic solute transporter subunit beta protein Pox_P35 PF03213.9 CBK23438.2 - 0.74 8.7 4.3 1.8 7.4 3.0 1.6 1 0 0 1 1 1 0 Poxvirus P35 protein Pex14_N PF04695.8 CBK23438.2 - 3.3 7.7 7.3 0.14 12.2 0.9 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2681 PF10883.3 CBK23438.2 - 4 7.7 9.0 2.7 8.2 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) SecY PF00344.15 CBK23439.2 - 7.5e-84 281.6 12.2 1.1e-83 281.0 8.4 1.2 1 0 0 1 1 1 1 SecY translocase Pkinase PF00069.20 CBK23439.2 - 1.1e-62 211.5 0.0 1.7e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23439.2 - 5.2e-28 97.8 0.0 8.2e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plug_translocon PF10559.4 CBK23439.2 - 3e-18 65.0 0.2 8.7e-18 63.5 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Kdo PF06293.9 CBK23439.2 - 0.0017 17.4 0.0 0.0078 15.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.1 CBK23439.2 - 0.0096 16.0 0.1 0.029 14.5 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBK23439.2 - 0.013 15.3 0.4 0.038 13.8 0.3 1.8 1 0 0 1 1 1 0 EF-hand domain EcKinase PF02958.15 CBK23439.2 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase EF-hand_1 PF00036.27 CBK23439.2 - 0.018 14.2 0.3 0.043 13.1 0.2 1.6 1 0 0 1 1 1 0 EF hand APH PF01636.18 CBK23439.2 - 0.044 13.5 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PCI PF01399.22 CBK23440.2 - 2e-14 53.7 3.0 2.5e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 PCI domain MarR_2 PF12802.2 CBK23440.2 - 0.0069 16.0 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.15 CBK23440.2 - 0.0089 16.1 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator TnpV PF14198.1 CBK23440.2 - 0.013 15.3 2.6 0.66 9.8 0.3 2.8 2 1 0 2 2 2 0 Transposon-encoded protein TnpV Sigma70_r4_2 PF08281.7 CBK23440.2 - 0.025 14.0 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 CBK23440.2 - 0.049 12.8 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TFCD_C PF12612.3 CBK23440.2 - 0.051 12.9 2.9 0.24 10.7 0.2 2.5 1 1 2 3 3 3 0 Tubulin folding cofactor D C terminal TrmB PF01978.14 CBK23440.2 - 0.11 12.2 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.1 CBK23440.2 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain SRA1 PF07304.6 CBK23441.2 - 0.11 12.2 1.0 16 5.2 0.1 2.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) DUF4611 PF15387.1 CBK23441.2 - 0.93 9.6 6.1 1.9 8.7 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.11 CBK23442.2 - 8.8e-07 27.9 3.7 1.1e-06 27.6 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SHR3_chaperone PF08229.6 CBK23442.2 - 0.00031 19.7 0.2 0.00031 19.7 0.1 1.8 2 0 0 2 2 2 1 ER membrane protein SH3 CDP-OH_P_tran_2 PF08009.6 CBK23442.2 - 0.028 14.1 2.6 0.028 14.1 1.8 2.6 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 MacB_PCD PF12704.2 CBK23442.2 - 0.033 13.7 0.6 0.5 9.9 0.6 2.0 2 0 0 2 2 2 0 MacB-like periplasmic core domain UPF0547 PF10571.4 CBK23444.2 - 0.18 11.5 0.3 0.18 11.5 0.2 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 CBK23444.2 - 1.6 8.0 9.6 1.1 8.4 4.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.18 CBK23445.2 - 8.2e-11 41.1 0.2 9.8e-11 40.9 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain FAM47 PF14642.1 CBK23445.2 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 FAM47 family RNA_pol_Rbc25 PF08292.7 CBK23446.2 - 0.012 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 WD40 PF00400.27 CBK23447.2 - 1.8e-40 135.3 0.0 2.5e-07 30.2 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBK23447.2 - 4.2e-24 84.2 0.4 8.3e-24 83.2 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CBK23448.2 - 4.9e-05 23.0 0.0 4.9e-05 23.0 0.0 3.0 5 0 0 5 5 5 1 WD domain, G-beta repeat RAP1 PF07218.6 CBK23448.2 - 8.2 4.3 9.7 11 3.9 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PHO4 PF01384.15 CBK23449.2 - 1.9e-107 358.7 19.1 2.5e-107 358.3 13.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Peptidase_M20 PF01546.23 CBK23450.2 - 4.8e-17 62.0 0.0 6.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBK23450.2 - 3.1e-07 30.1 0.1 7.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ATP-synt_ab PF00006.20 CBK23451.2 - 3.5e-60 203.1 0.0 4.6e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK23451.2 - 5.1e-13 49.4 0.0 9.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK23451.2 - 2.9e-10 40.2 0.5 5.2e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBK23451.2 - 0.0032 17.3 0.1 0.0071 16.2 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain 14-3-3 PF00244.15 CBK23452.2 - 2.8e-65 219.7 7.4 3.1e-65 219.5 5.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CBK23452.2 - 0.17 11.8 4.8 0.42 10.5 0.7 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 CBK23452.2 - 0.29 10.7 3.6 0.16 11.6 0.4 2.0 2 1 0 2 2 2 0 Archaeal ATPase TPR_1 PF00515.23 CBK23452.2 - 1.9 8.2 4.4 27 4.5 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TIP49 PF06068.8 CBK23454.2 - 3e-142 474.0 4.1 3.5e-142 473.8 2.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CBK23454.2 - 0.02 15.0 0.0 0.091 12.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain Sipho_tail PF05709.6 CBK23454.2 - 0.03 13.4 0.1 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein CENP-X PF09415.5 CBK23455.2 - 2.8e-12 46.2 0.3 3e-12 46.1 0.2 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Histone PF00125.19 CBK23455.2 - 0.1 12.7 0.2 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Limkain-b1 PF11608.3 CBK23455.2 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Limkain b1 Pkinase PF00069.20 CBK23457.2 - 3.7e-15 55.7 0.0 6.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23457.2 - 3.8e-05 22.8 0.0 0.00025 20.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DIM1 PF02966.11 CBK23457.2 - 0.084 12.3 0.0 12 5.4 0.0 2.7 3 0 0 3 3 3 0 Mitosis protein DIM1 Pkinase PF00069.20 CBK23458.2 - 1.1e-20 73.8 0.0 1.7e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23458.2 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BAF1_ABF1 PF04684.8 CBK23458.2 - 5.8 5.6 13.8 8.6 5.0 9.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RabGAP-TBC PF00566.13 CBK23459.2 - 2.5e-52 177.4 0.5 3.5e-52 176.9 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NAD_binding_1 PF00175.16 CBK23459.2 - 0.091 13.3 0.0 0.45 11.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain ETC_C1_NDUFA5 PF04716.9 CBK23460.2 - 2.1e-19 68.7 0.5 3.4e-19 68.0 0.4 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pkinase PF00069.20 CBK23461.2 - 2.1e-55 187.6 0.0 2.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23461.2 - 6.5e-17 61.4 0.0 1.7e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK23461.2 - 7.2e-07 29.1 0.0 2.2e-06 27.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBK23461.2 - 0.0029 17.1 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Trm112p PF03966.11 CBK23462.2 - 5.1e-13 49.1 0.0 6.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-BED PF02892.10 CBK23462.2 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Zn_ribbon_recom PF13408.1 CBK23462.2 - 0.05 13.8 0.2 0.095 12.9 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain HypA PF01155.14 CBK23462.2 - 0.092 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family MRP-L46 PF11788.3 CBK23463.2 - 0.037 14.6 0.1 0.037 14.6 0.1 2.5 3 0 0 3 3 3 0 39S mitochondrial ribosomal protein L46 5-FTHF_cyc-lig PF01812.15 CBK23464.2 - 8e-30 103.9 0.0 8.8e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GTP_EFTU PF00009.22 CBK23465.2 - 3.9e-46 156.8 0.0 5e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK23465.2 - 3.4e-21 75.2 0.6 2e-20 72.8 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK23465.2 - 2.6e-07 30.6 0.2 6.4e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK23465.2 - 0.0004 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBK23465.2 - 0.0046 16.5 0.1 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FeoB_N PF02421.13 CBK23465.2 - 0.087 12.0 0.1 2.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.1 CBK23465.2 - 0.1 12.1 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-RING_2 PF13639.1 CBK23466.2 - 6e-15 54.8 5.5 1.3e-14 53.7 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK23466.2 - 2.2e-10 40.4 3.5 4.3e-10 39.5 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBK23466.2 - 1e-08 34.7 3.0 2e-08 33.7 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23466.2 - 6.2e-08 32.1 5.7 1.4e-07 31.0 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23466.2 - 6.3e-08 32.2 4.5 1.2e-07 31.3 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK23466.2 - 4.1e-07 29.9 5.7 8.1e-07 28.9 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBK23466.2 - 0.00098 18.9 2.9 0.0026 17.5 2.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger IncA PF04156.9 CBK23466.2 - 0.003 17.1 6.6 0.003 17.1 4.6 2.2 2 0 0 2 2 2 1 IncA protein Prok-RING_1 PF14446.1 CBK23466.2 - 0.0031 17.2 3.7 0.012 15.2 2.6 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 CBK23466.2 - 0.014 15.2 6.5 0.017 15.0 3.2 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_PEP_C PF04513.7 CBK23466.2 - 0.016 14.9 2.0 0.46 10.3 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_4 PF14570.1 CBK23466.2 - 0.051 13.1 3.0 0.097 12.2 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBK23466.2 - 0.12 12.1 3.5 0.48 10.1 2.4 2.2 1 0 0 1 1 1 0 RING-type zinc-finger TFIIA_gamma_N PF02268.11 CBK23466.2 - 0.13 11.8 0.6 0.36 10.4 0.4 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Prok-RING_4 PF14447.1 CBK23466.2 - 0.21 11.1 6.7 0.72 9.4 4.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3508 PF12018.3 CBK23466.2 - 0.62 9.0 6.4 1.2 8.0 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) RINGv PF12906.2 CBK23466.2 - 0.71 9.9 6.2 0.69 9.9 3.0 2.0 1 1 1 2 2 2 0 RING-variant domain DUF4279 PF14106.1 CBK23466.2 - 0.72 9.7 4.2 1.1 9.1 1.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4279) Fzo_mitofusin PF04799.8 CBK23466.2 - 1.8 7.9 6.4 1.7 8.0 0.4 2.2 2 0 0 2 2 2 0 fzo-like conserved region PHD PF00628.24 CBK23466.2 - 6 6.6 7.7 1.9 8.2 3.2 1.8 2 0 0 2 2 1 0 PHD-finger TauE PF01925.14 CBK23467.2 - 1.7e-42 145.5 11.9 7.5e-23 81.2 0.5 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE UPF0016 PF01169.14 CBK23467.2 - 0.098 12.8 10.4 0.069 13.3 0.7 3.3 2 2 1 3 3 3 0 Uncharacterized protein family UPF0016 Lung_7-TM_R PF06814.8 CBK23468.2 - 2.1e-49 168.0 27.0 2.6e-49 167.8 18.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBK23468.2 - 0.00026 20.2 26.9 0.00069 18.8 17.0 2.2 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain ELMO_CED12 PF04727.8 CBK23468.2 - 0.13 11.7 1.7 0.23 11.0 1.2 1.3 1 0 0 1 1 1 0 ELMO/CED-12 family FG-GAP PF01839.18 CBK23469.2 - 0.0014 18.2 1.7 0.0014 18.2 1.2 2.5 2 0 0 2 2 2 1 FG-GAP repeat PQQ_2 PF13360.1 CBK23469.2 - 0.0067 15.9 0.0 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain Filamin PF00630.14 CBK23469.2 - 0.03 14.8 0.0 0.063 13.8 0.0 1.5 1 1 0 1 1 1 0 Filamin/ABP280 repeat VCBS PF13517.1 CBK23469.2 - 0.038 14.3 7.8 0.066 13.5 0.8 2.9 2 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Clathrin PF00637.15 CBK23470.2 - 1e-14 54.3 11.3 8.2e-14 51.4 4.4 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS Pep3_Vps18 PF05131.9 CBK23470.2 - 1.7e-11 43.7 0.0 3.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 CBK23470.2 - 9e-08 32.2 0.0 6.8e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CBK23470.2 - 0.0001 22.0 1.6 0.00033 20.4 1.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBK23470.2 - 0.0031 17.2 2.8 0.0058 16.3 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Apolipoprotein PF01442.13 CBK23470.2 - 0.012 15.1 3.7 0.15 11.5 0.7 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2758 PF10957.3 CBK23470.2 - 0.13 12.1 1.7 0.29 10.9 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) zf-C3HC4_2 PF13923.1 CBK23470.2 - 0.28 11.2 2.5 0.53 10.3 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23470.2 - 0.65 9.6 4.1 0.43 10.2 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aa_trans PF01490.13 CBK23471.2 - 1e-14 53.9 21.4 1.2e-14 53.6 14.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2039 PF10217.4 CBK23472.2 - 2.2e-27 94.9 15.6 2.2e-27 94.9 10.8 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) PHF5 PF03660.9 CBK23472.2 - 0.098 12.7 12.8 0.92 9.6 6.8 2.1 2 0 0 2 2 2 0 PHF5-like protein Ist1 PF03398.9 CBK23473.2 - 1.3e-12 47.4 3.8 2.3e-12 46.6 2.6 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hexapep PF00132.19 CBK23474.2 - 2.6e-15 55.1 13.1 1.7e-07 30.3 0.1 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBK23474.2 - 0.00021 20.7 15.5 0.00083 18.8 0.4 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CBK23474.2 - 0.1 11.1 3.3 0.29 9.6 1.5 1.9 1 1 1 2 2 2 0 L-fucokinase ATP_bind_1 PF03029.12 CBK23476.2 - 0.0078 15.7 0.0 0.0095 15.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RAP-1 PF03085.10 CBK23476.2 - 0.019 14.3 0.4 0.12 11.6 0.1 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) ADK PF00406.17 CBK23477.2 - 2.4e-36 124.9 0.0 2.9e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CBK23477.2 - 2.4e-11 44.0 0.1 2.4e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK23477.2 - 2.8e-08 33.7 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK23477.2 - 7.6e-07 29.9 0.7 1.1e-06 29.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBK23477.2 - 8.7e-07 28.2 0.0 2.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin CPT PF07931.7 CBK23477.2 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_PrkA PF08298.6 CBK23477.2 - 0.029 13.0 0.0 0.066 11.8 0.0 1.5 2 0 0 2 2 2 0 PrkA AAA domain CoaE PF01121.15 CBK23477.2 - 0.048 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_28 PF13521.1 CBK23477.2 - 0.09 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CBK23477.2 - 0.18 11.1 1.3 3.3 7.0 0.0 2.7 2 1 1 3 3 3 0 Thymidylate kinase LSM PF01423.17 CBK23478.2 - 9.1e-18 63.5 2.2 1.2e-17 63.1 1.5 1.2 1 0 0 1 1 1 1 LSM domain NaeI PF09126.5 CBK23478.2 - 0.13 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Sec1 PF00995.18 CBK23479.2 - 1.5e-44 152.5 0.4 1.1e-43 149.7 0.3 2.3 1 1 0 1 1 1 1 Sec1 family PH PF00169.24 CBK23479.2 - 0.036 14.2 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 PH domain OapA_N PF08525.6 CBK23479.2 - 0.13 12.0 1.7 7.4 6.4 0.2 2.8 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif WD40 PF00400.27 CBK23480.2 - 9.5e-28 95.0 33.4 4.1e-05 23.2 0.0 12.6 12 2 0 12 12 12 8 WD domain, G-beta repeat DUF1148 PF06618.6 CBK23480.2 - 0.028 14.3 0.1 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1148) Acetyltransf_1 PF00583.19 CBK23481.2 - 1.1e-12 47.7 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBK23481.2 - 2.1e-08 34.2 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBK23481.2 - 5.9e-07 29.6 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK23481.2 - 5.7e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CBK23481.2 - 0.00014 21.8 0.3 0.00018 21.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBK23481.2 - 0.00021 21.4 0.0 0.00022 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBK23481.2 - 0.00064 19.6 0.0 0.00089 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 CBK23481.2 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family TPR_11 PF13414.1 CBK23482.2 - 1.1e-22 79.3 5.1 4.5e-19 67.8 2.4 2.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBK23482.2 - 4.7e-14 51.0 4.3 2.1e-06 27.2 1.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23482.2 - 9.1e-13 47.2 5.0 3.8e-06 26.2 1.5 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23482.2 - 1.5e-07 31.9 0.6 2.8e-06 27.8 0.8 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK23482.2 - 1.5e-06 27.9 0.9 0.15 12.2 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23482.2 - 3e-06 27.0 0.9 0.11 12.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK23482.2 - 1.5e-05 24.7 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23482.2 - 0.0001 21.8 2.4 1.1 9.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23482.2 - 0.00042 20.5 0.6 0.04 14.2 0.0 2.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBK23482.2 - 0.00066 19.7 2.0 0.0026 17.8 0.5 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBK23482.2 - 0.0016 18.8 0.0 1.2 10.0 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBK23482.2 - 0.0056 17.0 0.5 0.19 12.2 0.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat SNAP PF14938.1 CBK23482.2 - 0.012 14.7 0.3 0.024 13.8 0.2 1.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CBK23482.2 - 0.029 14.1 2.0 0.35 10.7 0.2 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBK23482.2 - 0.065 13.0 0.5 0.19 11.5 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3785 PF12653.2 CBK23482.2 - 0.071 12.9 0.2 0.071 12.9 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) MIT PF04212.13 CBK23482.2 - 0.18 11.6 0.9 0.29 11.0 0.3 1.6 2 0 0 2 2 1 0 MIT (microtubule interacting and transport) domain DUF357 PF04010.8 CBK23482.2 - 2.5 7.8 6.5 1.9 8.2 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF357) adh_short PF00106.20 CBK23483.2 - 1.3e-26 93.5 0.0 1.9e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBK23483.2 - 7.5e-16 58.6 0.1 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DnaJ PF00226.26 CBK23483.2 - 5.3e-14 51.6 6.3 3.5e-13 49.0 0.1 2.9 2 1 1 3 3 3 2 DnaJ domain KR PF08659.5 CBK23483.2 - 7.2e-12 45.3 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBK23483.2 - 0.0003 20.8 0.0 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBK23483.2 - 0.00057 19.4 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CBK23483.2 - 0.002 17.3 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF4446 PF14584.1 CBK23483.2 - 0.81 9.5 5.1 2.5 7.9 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) IPPT PF01715.12 CBK23484.2 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 IPP transferase Ribosomal_L22e PF01776.12 CBK23485.2 - 1.1e-40 138.0 3.7 1.3e-40 137.8 2.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.3 CBK23485.2 - 0.021 15.0 0.3 0.037 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF2218 PF09981.4 CBK23485.2 - 0.1 12.8 0.6 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) HAD_2 PF13419.1 CBK23486.2 - 1.9e-16 60.7 0.1 2.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBK23486.2 - 2.5e-09 36.7 0.0 4.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Apyrase PF06079.6 CBK23487.2 - 1.8e-109 365.3 2.0 2.5e-109 364.9 1.4 1.2 1 0 0 1 1 1 1 Apyrase Sulfate_transp PF00916.15 CBK23487.2 - 3.3e-45 154.2 0.3 1.4e-44 152.2 0.2 2.1 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBK23487.2 - 1.4e-32 111.1 3.3 1.4e-32 111.1 2.3 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBK23487.2 - 3.5e-08 32.8 0.0 7.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CBK23487.2 - 0.00016 21.6 0.0 0.00042 20.3 0.0 1.7 1 0 0 1 1 1 1 STAS domain WhiA_N PF10298.4 CBK23487.2 - 0.17 11.7 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain Nuc_sug_transp PF04142.10 CBK23488.2 - 1.8e-06 27.2 0.3 2.2e-06 26.9 0.2 1.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CBK23488.2 - 0.0058 16.6 2.5 0.0066 16.4 1.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 CBK23488.2 - 0.018 14.7 1.3 0.02 14.5 0.9 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family UPF0546 PF10639.4 CBK23488.2 - 0.083 12.7 0.4 0.089 12.6 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 LSM PF01423.17 CBK23489.2 - 4.5e-14 51.7 0.5 5.6e-14 51.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain Img2 PF05046.9 CBK23489.2 - 0.064 13.4 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CKS PF01111.14 CBK23490.2 - 1.4e-28 98.4 0.3 1.9e-28 98.0 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PfkB PF00294.19 CBK23491.2 - 6.6e-17 61.5 0.1 8.1e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.19 CBK23492.2 - 1.5e-23 83.3 0.1 1.8e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UBA_4 PF14555.1 CBK23492.2 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.20 CBK23493.2 - 6.8e-71 238.4 0.0 1.2e-70 237.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23493.2 - 1.5e-52 178.2 0.0 2.5e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF21 PF01595.15 CBK23493.2 - 2.1e-28 98.8 0.2 7.1e-28 97.1 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBK23493.2 - 7.5e-05 22.4 1.1 0.095 12.5 0.1 2.7 2 0 0 2 2 2 2 CBS domain Kinase-like PF14531.1 CBK23493.2 - 0.022 13.7 0.0 0.087 11.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DSBA PF01323.15 CBK23495.2 - 0.0003 20.3 0.0 0.00033 20.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 CBK23495.2 - 0.07 13.1 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin ThiF PF00899.16 CBK23496.2 - 5e-25 87.9 0.6 8e-25 87.2 0.1 1.4 2 0 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.4 CBK23496.2 - 1.9e-12 46.3 3.0 3.7e-12 45.4 2.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 CBK23496.2 - 0.051 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein Vps51 PF08700.6 CBK23497.2 - 1e-05 25.2 1.7 2.9e-05 23.8 0.1 2.6 3 0 0 3 3 3 1 Vps51/Vps67 Zw10 PF06248.8 CBK23497.2 - 1.3e-05 23.6 1.0 1.3e-05 23.6 0.7 1.6 2 1 1 3 3 3 1 Centromere/kinetochore Zw10 DUF2450 PF10475.4 CBK23497.2 - 0.00019 20.4 0.7 0.00035 19.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF4363 PF14276.1 CBK23497.2 - 0.031 13.9 0.2 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pox_polyA_pol_N PF12630.2 CBK23497.2 - 0.063 13.3 1.8 0.14 12.2 0.9 1.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain LOH1CR12 PF10158.4 CBK23497.2 - 0.075 12.8 0.3 0.36 10.6 0.2 2.1 1 1 1 2 2 2 0 Tumour suppressor protein C5-epim_C PF06662.8 CBK23497.2 - 0.1 11.8 0.2 0.23 10.7 0.1 1.5 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus DUF2120 PF09893.4 CBK23497.2 - 0.11 12.4 3.2 23 4.9 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) E2F_TDP PF02319.15 CBK23498.2 - 1.9e-14 52.9 0.0 4.4e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Prefoldin_2 PF01920.15 CBK23498.2 - 0.021 14.6 0.2 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.20 CBK23499.2 - 7.8e-42 143.2 0.0 1e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23499.2 - 1e-22 80.4 0.0 1.2e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23499.2 - 3.2e-09 36.1 0.0 3.9e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK23499.2 - 7e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK23499.2 - 0.00031 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBK23499.2 - 0.027 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SET PF00856.23 CBK23500.2 - 1.9e-24 86.8 2.6 5.6e-24 85.2 1.8 1.8 1 1 0 1 1 1 1 SET domain FYRC PF05965.9 CBK23500.2 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus Bromodomain PF00439.20 CBK23501.2 - 5.5e-11 42.2 0.9 8.9e-11 41.5 0.2 1.7 2 0 0 2 2 2 1 Bromodomain PHD PF00628.24 CBK23501.2 - 6.6e-08 32.1 14.8 6.6e-08 32.1 10.2 3.2 3 1 0 3 3 3 2 PHD-finger DPBB_1 PF03330.13 CBK23501.2 - 0.87 9.6 3.5 10 6.1 2.0 2.3 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF389 PF04087.9 CBK23502.2 - 2.8e-35 121.2 4.2 3.6e-35 120.9 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF389) FtsX PF02687.16 CBK23502.2 - 3.5 7.4 17.8 1.1 8.9 1.8 2.8 1 1 2 3 3 3 0 FtsX-like permease family DUF1049 PF06305.6 CBK23502.2 - 8.3 5.9 10.5 0.41 10.1 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Dus PF01207.12 CBK23503.2 - 7.8e-37 126.7 0.0 4.5e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Bromodomain PF00439.20 CBK23504.2 - 5.5e-11 42.2 0.9 8.9e-11 41.5 0.2 1.7 2 0 0 2 2 2 1 Bromodomain PHD PF00628.24 CBK23504.2 - 6.6e-08 32.1 14.8 6.6e-08 32.1 10.2 3.2 3 1 0 3 3 3 2 PHD-finger DPBB_1 PF03330.13 CBK23504.2 - 0.87 9.6 3.5 10 6.1 2.0 2.3 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SET PF00856.23 CBK23505.2 - 2.4e-24 86.4 2.2 6.6e-24 85.0 1.5 1.8 1 1 0 1 1 1 1 SET domain Collagen PF01391.13 CBK23505.2 - 1.2e-08 34.3 12.2 3.2e-08 32.9 8.5 1.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_14 PF13428.1 CBK23506.2 - 2.2e-30 102.3 19.8 5.5e-05 23.4 0.1 12.5 7 6 6 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23506.2 - 5.3e-17 61.9 13.8 6.9e-05 23.1 0.5 7.5 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23506.2 - 1.1e-16 60.9 9.1 0.0024 18.5 0.1 8.1 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBK23506.2 - 3.3e-14 52.2 9.6 0.0035 16.9 0.2 7.1 6 1 2 8 8 8 5 TPR repeat PRP1_N PF06424.7 CBK23506.2 - 1.8e-10 41.2 1.2 1.8e-10 41.2 0.8 1.9 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.12 CBK23506.2 - 1.6e-09 36.9 10.1 0.0088 15.8 0.3 7.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 CBK23506.2 - 3.1e-08 33.7 0.0 0.056 13.1 0.0 4.5 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_17 PF13431.1 CBK23506.2 - 2.4e-07 30.4 8.7 0.25 11.6 0.2 7.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23506.2 - 1.1e-06 28.5 8.7 0.011 15.6 0.2 6.1 5 1 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 CBK23506.2 - 2e-05 23.6 12.9 0.011 14.5 1.4 4.7 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference RPN7 PF10602.4 CBK23506.2 - 0.00045 19.6 0.5 0.34 10.2 0.0 3.5 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 CBK23506.2 - 0.00067 19.2 6.2 0.22 11.3 0.4 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK23506.2 - 0.00095 18.9 2.8 1.5 8.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK23506.2 - 0.0031 17.8 7.9 0.51 10.9 0.5 6.1 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23506.2 - 0.0041 16.6 6.8 0.081 12.5 0.3 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 CBK23506.2 - 0.0062 15.3 0.1 3.8 6.1 0.0 3.6 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 CBK23506.2 - 0.014 15.5 2.1 2.5 8.2 0.0 4.3 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HAT PF02184.11 CBK23506.2 - 0.018 14.7 0.1 28 4.5 0.0 4.1 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat DUF3808 PF10300.4 CBK23506.2 - 0.033 12.7 2.8 7.6 4.9 0.0 4.3 4 1 0 5 5 5 0 Protein of unknown function (DUF3808) Mad3_BUB1_I PF08311.7 CBK23506.2 - 0.035 13.8 1.1 1.5 8.5 0.0 3.8 4 1 0 4 4 3 0 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 CBK23506.2 - 0.044 13.5 6.8 1 9.2 0.4 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Cadherin PF00028.12 CBK23507.2 - 6.3e-80 263.5 20.2 3.8e-11 43.0 0.0 14.6 14 0 0 14 14 14 13 Cadherin domain TIG PF01833.19 CBK23507.2 - 6.1e-52 173.5 77.5 2.2e-11 43.5 0.7 15.1 15 0 0 15 15 15 11 IPT/TIG domain TarH PF02203.10 CBK23507.2 - 2.2 8.0 0.3 37 4.1 0.3 2.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue Phage_lysis PF03245.8 CBK23507.2 - 5.8 6.9 3.9 10 6.1 2.7 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF462 PF04315.7 CBK23508.2 - 4.6e-13 48.8 1.1 24 4.2 0.0 16.2 20 0 0 20 20 20 3 Protein of unknown function, DUF462 DUF2254 PF10011.4 CBK23509.2 - 0.081 11.3 0.5 0.096 11.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) tRNA-synt_His PF13393.1 CBK23510.2 - 1.9e-29 102.7 0.0 3.2e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CBK23510.2 - 1.6e-18 66.8 0.0 2.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK23511.2 - 1.1e-09 38.1 0.1 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain RNA_polI_A34 PF08208.6 CBK23512.2 - 0.00021 21.0 0.1 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Brix PF04427.13 CBK23513.2 - 5.2e-41 140.4 0.4 5.2e-41 140.4 0.2 1.5 2 0 0 2 2 2 1 Brix domain Ribosomal_S8e PF01201.17 CBK23513.2 - 0.036 14.2 1.0 0.073 13.2 0.7 1.6 1 0 0 1 1 1 0 Ribosomal protein S8e 6PF2K PF01591.13 CBK23514.2 - 1e-43 148.9 0.0 1.6e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CBK23514.2 - 1.3e-26 93.5 0.0 5e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CBK23514.2 - 0.025 14.4 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1622 PF07784.6 CBK23514.2 - 0.049 13.2 0.2 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) DHDPS PF00701.17 CBK23515.2 - 2.6e-34 118.1 0.0 3.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CPSF_A PF03178.10 CBK23516.2 - 4.3e-53 180.4 0.0 7e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CBK23517.2 - 1.6e-08 33.1 0.0 2.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CTV_P33 PF07184.6 CBK23517.2 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein CBFD_NFYB_HMF PF00808.18 CBK23519.2 - 1.9e-17 63.0 3.9 3.2e-16 59.1 2.7 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK23519.2 - 1.8e-12 47.2 0.1 2.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBK23519.2 - 0.013 15.4 0.1 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Aminotran_4 PF01063.14 CBK23520.2 - 2e-22 79.8 0.0 2.4e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Thioredoxin PF00085.15 CBK23521.2 - 2e-29 101.3 0.3 1.2e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CBK23521.2 - 4e-08 33.4 0.5 0.00098 19.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 CBK23521.2 - 7.9e-07 29.0 3.4 7.6e-05 22.5 0.4 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK23521.2 - 4.4e-06 26.7 3.8 0.0035 17.4 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBK23521.2 - 4.8e-05 23.0 0.3 0.22 11.1 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.1 CBK23521.2 - 0.00027 20.9 0.2 0.68 9.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 CBK23521.2 - 0.0026 17.5 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 CBK23521.2 - 0.033 14.1 0.7 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin zf-FCS PF06467.9 CBK23521.2 - 0.045 13.3 0.6 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Sas10 PF09368.5 CBK23522.2 - 4e-25 87.7 5.6 4e-25 87.7 3.9 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CBK23522.2 - 0.00072 19.7 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Utp11 PF03998.8 CBK23524.2 - 1.1e-51 176.0 29.8 1.2e-51 175.8 20.7 1.0 1 0 0 1 1 1 1 Utp11 protein HemS PF05171.7 CBK23524.2 - 0.074 12.8 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain ACR_tran PF00873.14 CBK23524.2 - 3 5.1 10.4 3.4 4.9 0.2 2.0 1 1 1 2 2 2 0 AcrB/AcrD/AcrF family Serinc PF03348.10 CBK23525.2 - 7.6e-20 71.0 36.7 8.6e-18 64.2 25.4 2.1 1 1 0 1 1 1 1 Serine incorporator (Serinc) Fis1_TPR_C PF14853.1 CBK23526.2 - 3.5e-15 55.6 1.1 3.5e-15 55.6 0.8 1.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CBK23526.2 - 4.6e-11 41.8 0.0 8.2e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_11 PF13414.1 CBK23526.2 - 7.5e-07 28.7 0.3 7.8e-06 25.4 0.2 2.2 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBK23526.2 - 2.8e-05 23.9 0.7 8.6e-05 22.4 0.1 2.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK23526.2 - 2.9e-05 23.6 5.5 5.6e-05 22.7 0.2 3.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23526.2 - 0.00036 21.1 0.3 0.073 13.7 0.0 2.5 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBK23526.2 - 0.00085 19.6 0.4 0.92 10.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23526.2 - 0.0024 17.5 1.3 0.018 14.7 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23526.2 - 0.009 16.3 0.3 0.009 16.3 0.2 2.4 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK23526.2 - 0.011 15.8 0.7 36 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23526.2 - 0.045 14.4 0.2 0.58 10.9 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23526.2 - 0.068 12.8 3.7 0.094 12.3 0.3 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBK23526.2 - 0.085 12.8 1.0 0.46 10.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat COPI_C PF06957.6 CBK23526.2 - 0.097 11.1 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Peptidase_M26_C PF07580.9 CBK23526.2 - 0.099 10.9 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Mito_carr PF00153.22 CBK23527.2 - 2.3e-43 145.7 2.9 7.1e-16 57.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ETF_QO PF05187.8 CBK23528.2 - 9.1e-22 77.1 0.0 1.6e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CBK23528.2 - 9.3e-12 44.5 0.8 5.2e-05 22.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBK23528.2 - 1.1e-09 37.6 1.0 5.7e-05 22.1 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBK23528.2 - 9.4e-07 28.7 0.1 7.5e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CBK23528.2 - 9.8e-07 29.0 0.0 6.8e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBK23528.2 - 1e-06 28.7 0.0 2.1e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBK23528.2 - 1.2e-05 24.5 0.2 0.00076 18.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.14 CBK23528.2 - 2.8e-05 23.4 0.0 0.0088 15.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_oxidored PF12831.2 CBK23528.2 - 3.1e-05 23.2 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBK23528.2 - 0.00029 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CBK23528.2 - 0.00041 19.3 0.0 0.00065 18.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBK23528.2 - 0.00044 19.3 0.1 0.0036 16.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CBK23528.2 - 0.00089 17.8 0.4 0.00089 17.8 0.3 1.8 3 0 0 3 3 3 1 HI0933-like protein Fer4_7 PF12838.2 CBK23528.2 - 0.0029 17.9 1.7 0.0065 16.8 1.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK23528.2 - 0.04 13.7 0.7 0.094 12.5 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.22 CBK23528.2 - 0.09 13.2 0.7 18 5.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SAM_2 PF07647.12 CBK23528.2 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Trp_halogenase PF04820.9 CBK23528.2 - 0.15 10.6 0.2 0.46 9.0 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_9 PF13187.1 CBK23528.2 - 0.19 12.0 1.9 0.46 10.7 1.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK23528.2 - 0.22 11.5 2.9 0.23 11.4 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 CBK23528.2 - 4 7.2 6.8 0.24 11.0 0.7 2.1 3 0 0 3 3 3 0 4Fe-4S binding domain DUF4446 PF14584.1 CBK23529.2 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) FAM176 PF14851.1 CBK23529.2 - 0.0052 16.4 0.3 0.0066 16.1 0.2 1.1 1 0 0 1 1 1 1 FAM176 family TMEM51 PF15345.1 CBK23529.2 - 0.021 14.5 0.3 0.024 14.3 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1049 PF06305.6 CBK23529.2 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4381 PF14316.1 CBK23529.2 - 0.047 13.8 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SID-1_RNA_chan PF13965.1 CBK23529.2 - 0.05 11.7 0.1 0.055 11.6 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.10 CBK23529.2 - 0.055 13.5 0.1 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family MENTAL PF10457.4 CBK23529.2 - 0.056 13.0 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF2215 PF10225.4 CBK23529.2 - 0.079 12.3 0.5 0.09 12.2 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) TRAP_alpha PF03896.11 CBK23529.2 - 0.11 11.4 0.1 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Inp1 PF12634.2 CBK23529.2 - 0.24 11.0 1.1 0.3 10.7 0.8 1.1 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 WGG PF10273.4 CBK23530.2 - 1.1e-11 44.6 0.8 2.1e-11 43.7 0.6 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Abhydrolase_6 PF12697.2 CBK23531.2 - 2.3e-08 34.1 0.1 3.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CBK23531.2 - 2.4e-05 24.0 0.3 0.00012 21.7 0.2 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CBK23531.2 - 0.0016 17.7 0.2 0.016 14.5 0.2 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CBK23531.2 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-RING_2 PF13639.1 CBK23533.2 - 6.6e-12 45.0 11.9 1.5e-11 43.8 8.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK23533.2 - 1.5e-07 31.3 5.9 1.5e-07 31.3 4.1 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBK23533.2 - 8.6e-07 28.5 8.1 1.5e-06 27.7 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23533.2 - 2.8e-05 23.7 10.8 5.2e-05 22.8 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBK23533.2 - 4e-05 23.3 5.4 9.9e-05 22.1 3.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CBK23533.2 - 6.1e-05 22.9 12.9 0.00013 21.9 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23533.2 - 0.00014 21.4 13.1 0.0003 20.3 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBK23533.2 - 0.026 14.4 11.9 0.24 11.3 8.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBK23533.2 - 0.08 12.6 8.9 0.063 13.0 2.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 CBK23533.2 - 0.1 12.7 4.0 0.67 10.1 3.0 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.2 CBK23533.2 - 0.38 10.8 13.4 0.19 11.7 7.7 1.7 2 0 0 2 2 2 0 RING-variant domain Claudin_2 PF13903.1 CBK23533.2 - 4.5 6.9 17.0 2.7 7.6 3.6 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RRM_1 PF00076.17 CBK23534.2 - 1.2e-32 111.3 0.4 1.4e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23534.2 - 2.5e-28 97.8 0.2 6.5e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23534.2 - 2.2e-12 46.6 0.3 1.8e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CBK23534.2 - 0.18 9.9 2.8 0.19 9.8 1.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PGI PF00342.14 CBK23535.2 - 1.9e-192 640.0 0.0 2.2e-192 639.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Imm22 PF15592.1 CBK23535.2 - 0.09 13.0 0.1 6 7.2 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 22 Lysine_decarbox PF03641.9 CBK23536.2 - 5.9e-13 48.7 0.0 6.6e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Possible lysine decarboxylase RRM_2 PF04059.7 CBK23537.2 - 2.6e-08 33.7 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 CBK23537.2 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23537.2 - 0.00027 20.8 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 CBK23537.2 - 0.085 12.8 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Ank_2 PF12796.2 CBK23538.2 - 3.2e-29 101.0 2.3 1.6e-15 57.1 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBK23538.2 - 1.5e-25 87.6 12.2 2.3e-06 27.1 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CBK23538.2 - 6.2e-25 86.6 10.1 2.6e-07 30.6 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK23538.2 - 6.1e-23 78.6 6.2 2.5e-05 24.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBK23538.2 - 5.1e-20 71.4 9.6 8e-11 42.1 0.3 4.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Shikimate_DH PF01488.15 CBK23538.2 - 0.084 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase VEFS-Box PF09733.4 CBK23538.2 - 0.14 11.8 0.3 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Alpha_adaptin_C PF02296.11 CBK23539.2 - 0.047 13.6 0.3 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain DUF966 PF06136.8 CBK23539.2 - 0.14 11.5 13.8 0.22 10.9 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.1 CBK23539.2 - 0.15 12.4 10.7 0.29 11.4 7.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Na_trans_assoc PF06512.8 CBK23539.2 - 0.31 10.9 8.5 0.62 9.9 5.9 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIA PF03153.8 CBK23539.2 - 0.56 10.0 15.1 0.9 9.3 10.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MORN_2 PF07661.8 CBK23541.2 - 0.075 13.0 12.1 0.24 11.5 0.0 3.9 5 0 0 5 5 5 0 MORN repeat variant IlvGEDA_leader PF08046.6 CBK23541.2 - 1.3 8.2 5.0 2.2 7.5 3.4 1.2 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Arm PF00514.18 CBK23542.2 - 2.2e-58 192.2 20.8 8.1e-13 47.6 0.1 8.4 9 1 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBK23542.2 - 8.2e-23 80.2 2.5 2.3e-05 24.7 0.0 5.5 5 3 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.1 CBK23542.2 - 7.4e-22 77.4 0.0 2.7e-07 30.7 0.0 4.6 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.17 CBK23542.2 - 7.2e-19 66.1 2.2 0.00033 20.4 0.0 6.8 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 CBK23542.2 - 5.1e-08 32.3 0.0 0.063 12.3 0.0 3.1 1 1 1 3 3 3 3 Armadillo-like Atx10homo_assoc PF09759.4 CBK23542.2 - 1.4e-05 24.7 5.1 0.012 15.3 0.0 4.4 2 1 3 6 6 6 3 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.15 CBK23542.2 - 1.4e-05 23.6 0.2 0.0074 14.6 0.1 2.3 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.1 CBK23542.2 - 9.9e-05 22.2 3.7 4.8 7.1 0.0 4.8 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 UNC45-central PF11701.3 CBK23542.2 - 0.00075 19.1 1.0 0.39 10.3 0.0 3.5 2 1 1 4 4 4 1 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.3 CBK23542.2 - 0.003 17.4 0.0 0.5 10.2 0.0 3.3 2 1 2 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.11 CBK23542.2 - 0.049 14.1 0.2 6.5 7.5 0.0 4.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat YadA_stalk PF05662.9 CBK23542.2 - 0.11 12.2 0.4 0.36 10.6 0.2 1.9 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin ABC_tran PF00005.22 CBK23544.2 - 1.7e-05 25.1 0.0 2.1e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Thioredoxin PF00085.15 CBK23545.2 - 5.9e-26 90.1 0.0 1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBK23545.2 - 1.6e-05 24.8 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK23545.2 - 1.8e-05 24.9 0.1 0.00044 20.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK23545.2 - 0.00073 19.6 0.0 0.021 14.9 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CBK23545.2 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 CBK23545.2 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 CBK23545.2 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain ATPase_gene1 PF09527.5 CBK23545.2 - 0.23 11.2 2.9 16 5.3 1.1 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) MacB_PCD PF12704.2 CBK23545.2 - 0.26 10.8 1.0 0.63 9.5 0.0 1.9 2 0 0 2 2 2 0 MacB-like periplasmic core domain eIF-3_zeta PF05091.7 CBK23546.2 - 5.8e-100 335.3 2.5 7.5e-100 334.9 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_L27 PF01016.14 CBK23547.2 - 4.6e-35 119.2 0.2 5.4e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Pkinase PF00069.20 CBK23548.2 - 7.4e-10 38.4 0.0 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23548.2 - 0.00094 18.3 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23548.2 - 0.0026 16.7 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ANTH PF07651.11 CBK23548.2 - 0.068 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 ANTH domain PAZ PF02170.17 CBK23548.2 - 0.075 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 PAZ domain Pkinase_Tyr PF07714.12 CBK23550.2 - 3.2e-66 223.0 0.0 4.3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBK23550.2 - 2e-56 191.0 0.0 2.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.1 CBK23552.2 - 0.011 15.4 0.4 6.8 6.5 0.0 2.6 2 1 0 2 2 2 0 Leucine rich repeat MORN_2 PF07661.8 CBK23552.2 - 0.22 11.6 9.9 7.6 6.9 0.5 4.0 3 0 0 3 3 3 0 MORN repeat variant PP2C PF00481.16 CBK23553.2 - 5.2e-47 160.3 0.0 5.2e-47 160.3 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CBK23553.2 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CDC45 PF02724.9 CBK23553.2 - 0.14 10.1 22.4 0.19 9.7 15.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CBK23553.2 - 0.21 9.4 23.0 0.26 9.1 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.1 CBK23553.2 - 0.59 8.5 10.5 0.74 8.2 7.3 1.1 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 CBK23553.2 - 1.6 7.0 29.2 2.2 6.6 20.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HOOK PF05622.7 CBK23554.2 - 3.9e-07 28.3 0.2 3.9e-07 28.3 0.1 4.2 2 1 2 4 4 4 2 HOOK protein CH PF00307.26 CBK23554.2 - 4.5e-06 26.6 0.0 1.7e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain ADIP PF11559.3 CBK23554.2 - 0.0071 16.2 14.8 0.0071 16.2 10.3 6.0 2 2 2 5 5 5 1 Afadin- and alpha -actinin-Binding FliD_N PF02465.13 CBK23554.2 - 7.7 6.9 21.5 18 5.8 0.1 5.0 3 2 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_S4 PF00163.14 CBK23555.2 - 3.6e-20 72.1 0.4 7.2e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBK23555.2 - 6.3e-13 47.9 0.4 6.3e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.7 CBK23555.2 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger RRM_1 PF00076.17 CBK23556.2 - 1.6e-08 34.0 0.0 2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23556.2 - 4.7e-08 32.7 0.0 5.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23556.2 - 0.00014 21.7 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK23556.2 - 0.042 13.6 0.0 0.047 13.4 0.0 1.0 1 0 0 1 1 1 0 Limkain b1 CoA_binding PF02629.14 CBK23557.2 - 1.2e-28 99.4 1.6 1.2e-28 99.4 1.1 2.6 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBK23557.2 - 1.9e-23 82.7 0.1 3.8e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBK23557.2 - 2.2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK23557.2 - 3.5e-05 23.9 0.0 9.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CBK23557.2 - 0.0058 17.1 0.1 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PFK PF00365.15 CBK23558.2 - 1.3e-31 109.6 1.4 2.2e-31 108.8 1.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 CBK23558.2 - 0.046 12.4 0.0 0.046 12.4 0.0 1.5 2 0 0 2 2 2 0 ATP-NAD kinase DAGK_cat PF00781.19 CBK23558.2 - 0.34 10.3 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TrmE_N PF10396.4 CBK23559.2 - 4.6e-31 107.1 0.0 1.4e-30 105.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CBK23559.2 - 7.8e-20 70.9 0.1 2e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CBK23559.2 - 4.3e-19 68.6 2.7 4.3e-19 68.6 1.8 3.2 2 1 1 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CBK23559.2 - 9.2e-11 41.2 0.9 2.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 CBK23559.2 - 2.7e-06 27.8 0.0 7.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 CBK23559.2 - 1.3e-05 25.5 0.4 0.00072 19.8 0.3 2.4 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 CBK23559.2 - 9.2e-05 22.3 0.0 0.00027 20.7 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Ras PF00071.17 CBK23559.2 - 0.0011 18.3 0.2 0.011 15.1 0.1 2.2 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 CBK23559.2 - 0.0015 18.0 2.2 0.0061 16.0 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBK23559.2 - 0.0024 17.0 0.4 0.011 14.9 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBK23559.2 - 0.0031 17.6 0.4 0.044 13.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 CBK23559.2 - 0.0085 15.5 0.0 0.067 12.6 0.0 2.2 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CBK23559.2 - 0.024 14.0 0.2 0.83 9.1 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CBK23559.2 - 0.051 12.9 0.5 1.1 8.5 0.4 2.5 1 1 0 1 1 1 0 AAA domain Y_phosphatase PF00102.22 CBK23560.2 - 4.5e-07 29.4 0.0 5.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBK23560.2 - 1.5e-05 24.6 0.0 4e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBK23560.2 - 0.001 19.3 0.1 0.0021 18.3 0.1 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBK23560.2 - 0.027 14.5 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myb_DNA-binding PF00249.26 CBK23562.2 - 0.029 14.4 0.4 0.051 13.6 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain NPR3 PF03666.8 CBK23563.2 - 1.4e-19 69.9 7.5 4.5e-18 65.0 5.2 2.1 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Big_5 PF13205.1 CBK23564.2 - 1.5e-11 44.8 0.5 0.0055 17.2 0.0 4.4 3 1 1 4 4 4 3 Bacterial Ig-like domain DUF1336 PF07059.7 CBK23565.2 - 6.8e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Trypan_PARP PF05887.6 CBK23566.2 - 0.46 10.3 12.6 1 9.1 8.7 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neur_chan_memb PF02932.11 CBK23566.2 - 1.3 8.8 4.2 2.3 8.0 2.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CBK23566.2 - 3.4 5.5 11.0 5 5.0 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CBK23566.2 - 3.4 5.2 8.1 4.3 4.9 5.6 1.1 1 0 0 1 1 1 0 Ycf1 Sec7 PF01369.15 CBK23567.2 - 2.7e-62 209.8 0.9 4.2e-62 209.1 0.7 1.3 1 0 0 1 1 1 1 Sec7 domain Phosphorylase PF00343.15 CBK23569.2 - 9.4e-292 969.2 1.5 1.1e-291 968.9 1.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF4243 PF14027.1 CBK23570.2 - 0.065 12.6 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Nicastrin PF05450.10 CBK23571.2 - 0.024 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Nicastrin HSP70 PF00012.15 CBK23572.2 - 2.6e-31 108.2 0.3 3e-31 108.0 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23572.2 - 4.2e-13 48.5 0.1 6.8e-13 47.8 0.1 1.4 2 0 0 2 2 2 1 MreB/Mbl protein MutL PF13941.1 CBK23572.2 - 6.5e-05 21.4 0.0 9.5e-05 20.9 0.0 1.2 1 0 0 1 1 1 1 MutL protein StbA PF06406.6 CBK23572.2 - 0.0013 17.7 0.1 0.0031 16.4 0.0 1.5 1 1 0 2 2 2 1 StbA protein Hydantoinase_A PF01968.13 CBK23572.2 - 0.0044 16.1 0.8 0.022 13.8 0.4 1.9 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase EutA PF06277.6 CBK23572.2 - 0.0053 15.4 0.0 0.0065 15.1 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA SrfB PF07520.6 CBK23572.2 - 0.0069 13.9 0.1 0.0093 13.5 0.1 1.2 1 0 0 1 1 1 1 Virulence factor SrfB Ppx-GppA PF02541.11 CBK23572.2 - 0.016 14.4 0.1 0.022 13.9 0.1 1.5 1 1 0 1 1 1 0 Ppx/GppA phosphatase family PilM_2 PF11104.3 CBK23572.2 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Actin PF00022.14 CBK23572.2 - 0.031 12.6 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Actin DDR PF08841.5 CBK23572.2 - 0.036 12.9 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CBK23572.2 - 0.12 12.1 1.6 0.17 11.7 0.4 1.8 2 0 0 2 2 2 0 Cell division protein FtsA DEAD PF00270.24 CBK23573.2 - 7.8e-06 25.4 0.0 9.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase TMF_DNA_bd PF12329.3 CBK23574.2 - 0.013 15.3 8.2 0.013 15.3 5.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MCPsignal PF00015.16 CBK23575.2 - 0.034 13.7 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Peptidase_M3 PF01432.15 CBK23576.2 - 1e-125 420.3 0.0 1.2e-125 420.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 PMM PF03332.8 CBK23578.2 - 2.1e-94 315.2 0.9 2.8e-94 314.8 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase WD40 PF00400.27 CBK23578.2 - 2.4e-25 87.4 20.2 9.3e-08 31.6 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Hydrolase_3 PF08282.7 CBK23578.2 - 2.6e-05 23.9 0.0 0.00058 19.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TFIIIC_delta PF12657.2 CBK23578.2 - 0.01 15.5 0.4 0.69 9.6 0.0 3.2 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term CTV_P13 PF06922.6 CBK23578.2 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein He_PIG PF05345.7 CBK23579.2 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.15 CBK23579.2 - 0.0054 17.0 3.4 0.015 15.6 0.4 2.6 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SNARE_assoc PF09335.6 CBK23579.2 - 0.014 15.5 0.7 0.21 11.7 0.2 2.5 2 1 1 3 3 3 0 SNARE associated Golgi protein P12 PF12669.2 CBK23579.2 - 0.087 13.0 1.0 0.22 11.7 0.7 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family RRM_1 PF00076.17 CBK23580.2 - 2.6e-17 62.1 1.0 0.00011 21.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23580.2 - 4.4e-16 58.6 0.1 5.1e-12 45.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23580.2 - 8.2e-09 35.1 0.4 0.039 13.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 CBK23581.2 - 3.8e-28 98.0 0.1 5.5e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK23581.2 - 5.2e-13 48.8 0.0 9.6e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBK23581.2 - 6.1e-10 38.6 0.0 1.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.16 CBK23581.2 - 3.1e-05 23.1 0.1 0.00012 21.2 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 CBK23581.2 - 0.002 17.6 0.1 0.23 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CBK23581.2 - 0.022 14.8 0.0 0.08 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PAXNEB PF05625.6 CBK23581.2 - 0.053 12.3 0.4 0.19 10.4 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein ATP-synt_ab PF00006.20 CBK23583.2 - 7e-109 362.3 0.0 1e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK23583.2 - 4.1e-25 88.4 0.4 8.2e-25 87.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK23583.2 - 8e-13 48.4 2.4 2.6e-12 46.7 0.2 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_17 PF13207.1 CBK23583.2 - 0.032 15.0 0.1 0.53 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBK23583.2 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK23583.2 - 0.085 12.8 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_L24e PF01246.15 CBK23584.2 - 6.7e-23 80.3 1.7 6.7e-23 80.3 1.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Phospholip_A2_1 PF00068.14 CBK23584.2 - 0.03 14.5 0.1 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A2 Longin PF13774.1 CBK23585.2 - 9.1e-15 53.9 0.0 1.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBK23585.2 - 7.6e-11 41.4 1.0 1.6e-10 40.4 0.7 1.5 1 0 0 1 1 1 1 Synaptobrevin Sin3_corepress PF08295.7 CBK23586.2 - 1.7e-20 72.6 0.0 4.3e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 CBK23586.2 - 1.1e-17 63.3 0.3 3.1e-08 33.1 0.0 3.8 3 0 0 3 3 3 2 Paired amphipathic helix repeat MFS_1 PF07690.11 CBK23587.2 - 4.3e-31 107.8 5.5 6.8e-31 107.2 3.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK23587.2 - 1.1e-15 57.1 5.2 1.1e-15 57.1 3.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CBK23587.2 - 6.2e-12 44.3 10.0 9.5e-07 27.2 0.8 3.0 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 CBK23587.2 - 0.0066 14.6 0.6 0.011 13.9 0.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4514 PF14986.1 CBK23587.2 - 1.9 8.3 5.7 2.9 7.7 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4514) ELF PF03317.8 CBK23587.2 - 1.9 7.6 4.7 1.1 8.4 0.4 2.1 2 0 0 2 2 2 0 ELF protein zf-CCCH PF00642.19 CBK23589.2 - 2.3e-07 30.2 13.4 0.00012 21.6 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBK23589.2 - 1.6 8.8 10.8 0.58 10.2 0.7 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type UDPG_MGDP_dh_N PF03721.9 CBK23591.2 - 8.7e-47 158.8 0.1 1.7e-46 157.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CBK23591.2 - 1.8e-34 118.0 0.1 5.7e-33 113.2 0.1 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CBK23591.2 - 6.5e-32 109.6 0.0 1.4e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 CBK23591.2 - 0.024 14.3 0.1 0.93 9.2 0.0 2.6 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus LRR_8 PF13855.1 CBK23592.2 - 7.2e-08 32.0 2.6 0.00041 20.0 0.1 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 CBK23592.2 - 2.1e-05 24.0 0.1 0.0003 20.3 0.0 2.4 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBK23592.2 - 0.037 14.0 0.7 25 5.3 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat MORN PF02493.15 CBK23592.2 - 0.23 11.2 11.3 0.35 10.6 1.6 3.6 3 0 0 3 3 3 0 MORN repeat WD40 PF00400.27 CBK23593.2 - 2.1e-34 116.1 8.2 4.6e-07 29.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBK23593.2 - 7.7e-11 41.7 0.1 2.7e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TP6A_N PF04406.9 CBK23594.2 - 0.0099 15.5 0.3 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase PGM_PMM_I PF02878.11 CBK23595.2 - 4.9e-14 51.9 0.1 8.8e-09 34.9 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CBK23595.2 - 5.7e-10 39.0 0.2 1.5e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CBK23595.2 - 9.3e-07 29.1 0.0 4.1e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBK23595.2 - 1.8e-06 27.9 0.0 4.6e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III AcetylCoA_hyd_C PF13336.1 CBK23596.2 - 7.4e-63 210.8 0.0 1.1e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 CBK23596.2 - 7.7e-21 74.7 0.0 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Syntaxin PF00804.20 CBK23597.2 - 7.1e-09 35.7 4.7 1e-08 35.2 3.3 1.3 1 0 0 1 1 1 1 Syntaxin Syntaxin-6_N PF09177.6 CBK23597.2 - 0.0021 18.4 3.9 0.003 17.9 1.7 1.8 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SPO22 PF08631.5 CBK23597.2 - 0.026 13.5 0.9 0.032 13.3 0.6 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Spc7 PF08317.6 CBK23597.2 - 0.19 10.3 5.5 0.25 9.9 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 CBK23597.2 - 1.9 7.6 7.2 0.4 9.8 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) Syntaxin_2 PF14523.1 CBK23597.2 - 4.9 7.2 8.6 7.6 6.6 3.9 2.4 1 1 1 2 2 2 0 Syntaxin-like protein ABC_tran PF00005.22 CBK23598.2 - 1.3e-29 103.2 0.0 2.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK23598.2 - 7.5e-11 42.5 1.3 6.2e-07 29.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBK23598.2 - 0.00034 19.9 0.6 0.2 10.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBK23598.2 - 0.00038 20.5 0.4 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK23598.2 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA12 PF10443.4 CBK23598.2 - 0.0026 16.3 0.0 0.0037 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein SbcCD_C PF13558.1 CBK23598.2 - 0.004 17.0 0.1 0.049 13.5 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBK23598.2 - 0.02 14.4 0.1 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CBK23598.2 - 0.031 13.9 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 CBK23598.2 - 0.032 15.0 0.6 0.12 13.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK23598.2 - 0.037 12.9 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 CBK23598.2 - 0.038 13.1 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CBK23598.2 - 0.068 13.0 0.1 0.18 11.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK23598.2 - 0.079 12.3 0.1 3 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 CBK23598.2 - 0.1 11.9 0.3 0.9 8.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBK23598.2 - 0.11 12.6 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CBK23598.2 - 0.15 12.3 2.8 0.29 11.4 1.9 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBK23598.2 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Cir_Bir_Yir PF06022.6 CBK23599.2 - 0.066 12.4 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir SopD PF11047.3 CBK23599.2 - 0.19 10.6 0.1 0.19 10.6 0.0 1.4 2 0 0 2 2 2 0 Salmonella outer protein D TUG-UBL1 PF11470.3 CBK23601.2 - 0.22 11.4 2.8 13 5.7 0.0 4.0 4 0 0 4 4 4 0 GLUT4 regulating protein TUG Ras PF00071.17 CBK23602.2 - 6.3e-30 103.7 0.2 6.8e-30 103.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK23602.2 - 1.2e-13 51.5 0.1 1.4e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK23602.2 - 9.4e-08 31.4 0.0 1.1e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK23602.2 - 0.00017 20.8 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK23602.2 - 0.00066 19.6 0.0 0.00077 19.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK23602.2 - 0.0058 15.8 0.0 0.0067 15.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CBK23602.2 - 0.033 14.0 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK23602.2 - 0.069 13.1 0.0 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 CBK23602.2 - 0.1 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBK23602.2 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase Cyclin PF08613.6 CBK23603.2 - 5.8e-27 94.9 0.8 7.8e-27 94.5 0.5 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBK23603.2 - 1.3e-11 44.1 0.3 1.7e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain IKKbetaNEMObind PF12179.3 CBK23603.2 - 0.061 13.1 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain V-SNARE_C PF12352.3 CBK23604.2 - 4.2e-07 29.9 0.3 4.2e-07 29.9 0.2 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBK23604.2 - 0.00013 21.5 2.4 0.0071 16.0 0.1 2.6 2 1 0 2 2 2 2 Sec20 ABC2_membrane_6 PF06182.6 CBK23604.2 - 0.015 14.8 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Glucos_trans_II PF14264.1 CBK23604.2 - 0.017 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII ACP53EA PF06313.6 CBK23604.2 - 0.027 14.3 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 Drosophila ACP53EA protein NPV_P10 PF05531.7 CBK23604.2 - 0.064 13.5 2.3 0.23 11.7 0.1 2.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein UDPGP PF01704.13 CBK23605.2 - 3.2e-21 75.3 0.0 4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sec62 PF03839.11 CBK23606.2 - 3.8e-15 55.9 0.1 4.8e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 RhoGAP PF00620.22 CBK23607.2 - 9e-12 44.8 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 CBK23607.2 - 4e-09 36.4 0.1 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain RNA_polI_A14 PF08203.6 CBK23607.2 - 0.058 13.6 0.1 2 8.6 0.0 2.9 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 SNF2_N PF00176.18 CBK23608.2 - 4.9e-54 183.1 1.4 4.9e-54 183.1 1.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK23608.2 - 2.2e-11 43.4 0.0 6.1e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK23608.2 - 6e-06 25.8 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TFIIA PF03153.8 CBK23608.2 - 0.00062 19.7 2.3 0.00062 19.7 1.6 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Denso_VP4 PF02336.10 CBK23608.2 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Capsid protein VP4 CENP-B_dimeris PF09026.5 CBK23608.2 - 1.2 9.4 11.8 3.9 7.7 8.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 CBK23608.2 - 3.3 6.6 9.3 6.7 5.6 6.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_1 PF00076.17 CBK23609.2 - 4.7e-11 42.1 0.1 7.9e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23609.2 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23609.2 - 6.2e-05 22.7 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma70_ner PF04546.8 CBK23609.2 - 0.029 13.9 15.8 0.047 13.2 11.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 CBK23609.2 - 0.067 11.2 19.2 0.085 10.8 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CBK23609.2 - 0.11 11.9 14.8 0.2 11.1 10.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 CBK23609.2 - 0.12 11.8 14.4 0.18 11.2 10.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin SLX9 PF15341.1 CBK23609.2 - 0.13 12.6 15.7 0.2 12.1 10.9 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 BTV_NS2 PF04514.7 CBK23609.2 - 0.15 10.9 15.1 0.23 10.3 10.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TSA PF03249.8 CBK23609.2 - 0.2 10.1 2.2 0.28 9.6 1.5 1.1 1 0 0 1 1 1 0 Type specific antigen DUF2457 PF10446.4 CBK23609.2 - 0.25 10.0 19.6 0.36 9.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ycf1 PF05758.7 CBK23609.2 - 0.5 8.0 9.2 0.61 7.7 6.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF2722 PF10846.3 CBK23609.2 - 0.59 9.0 7.7 0.73 8.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.7 CBK23609.2 - 1.3 8.2 9.8 1.9 7.6 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3684 PF12449.3 CBK23609.2 - 1.3 6.4 4.7 1.7 6.1 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Nop14 PF04147.7 CBK23609.2 - 1.9 6.3 21.1 2.7 5.8 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 CBK23609.2 - 2 8.1 17.7 0.035 13.9 6.8 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal RRN3 PF05327.6 CBK23609.2 - 2.3 6.2 7.4 2.6 6.0 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleo_P87 PF07267.6 CBK23609.2 - 3.2 6.3 12.6 4 6.0 8.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.5 CBK23609.2 - 3.3 6.8 21.3 4.2 6.4 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UPF0560 PF10577.4 CBK23609.2 - 5.8 5.0 10.0 7.2 4.7 6.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tom22 PF04281.8 CBK23609.2 - 6.8 6.2 15.1 12 5.4 10.5 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CENP-B_dimeris PF09026.5 CBK23609.2 - 9.1 6.5 17.5 19 5.5 12.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sec1 PF00995.18 CBK23610.2 - 9.6e-13 47.6 0.5 3.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Sec1 family Gemini_AL1_M PF08283.6 CBK23610.2 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Geminivirus rep protein central domain Mpv17_PMP22 PF04117.7 CBK23611.2 - 0.92 9.1 4.9 0.8 9.3 2.1 1.8 1 1 1 2 2 2 0 Mpv17 / PMP22 family P5CR_dimer PF14748.1 CBK23612.2 - 3.1e-37 126.8 0.0 4.4e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBK23612.2 - 2.6e-09 37.3 0.0 7.1e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBK23612.2 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2576 PF10845.3 CBK23613.2 - 0.12 11.5 0.9 0.15 11.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) UPF0020 PF01170.13 CBK23614.2 - 0.00056 19.5 0.0 0.0048 16.4 0.0 2.3 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBK23614.2 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SART-1 PF03343.8 CBK23615.2 - 1.8e-18 66.2 1.7 1.2e-12 46.9 0.4 3.1 3 0 0 3 3 3 2 SART-1 family DUF1777 PF08648.7 CBK23615.2 - 1.3e-05 25.0 40.1 1.3e-05 25.0 27.8 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) SART-1 PF03343.8 CBK23616.2 - 2.1e-16 59.4 4.2 9.5e-15 53.9 2.9 2.0 1 1 0 1 1 1 1 SART-1 family Tom37_C PF11801.3 CBK23617.2 - 4 7.2 8.6 0.45 10.3 1.7 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain TPR_14 PF13428.1 CBK23620.2 - 9.2e-10 38.2 22.5 0.031 14.9 0.0 8.4 5 4 5 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23620.2 - 3.8e-09 36.7 22.6 0.023 15.0 2.3 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23620.2 - 3.8e-07 30.6 17.9 0.039 14.6 1.6 6.0 4 1 0 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 CBK23620.2 - 9.8e-06 24.5 6.0 0.0003 19.6 1.9 2.8 3 1 0 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CBK23620.2 - 1.9e-05 24.1 15.2 0.32 10.6 0.0 6.0 6 2 2 8 8 8 3 TPR repeat Suf PF05843.9 CBK23620.2 - 0.001 18.8 3.6 0.031 13.9 0.0 3.0 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBK23620.2 - 0.0082 15.9 16.7 3.1 7.9 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat Nucleoplasmin PF03066.10 CBK23620.2 - 0.038 13.5 0.8 0.067 12.7 0.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin TPR_17 PF13431.1 CBK23620.2 - 0.56 10.5 5.0 18 5.8 0.0 5.6 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23620.2 - 1.2 9.0 18.8 7 6.6 0.0 6.1 9 0 0 9 9 9 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.5 CBK23620.2 - 3.4 7.9 8.2 8.9 6.6 5.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CBK23620.2 - 7.4 6.9 10.5 1.1 9.5 4.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ldh_1_N PF00056.18 CBK23621.2 - 1.3e-40 138.4 0.1 2.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBK23621.2 - 2.2e-34 118.6 0.0 3e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CBK23621.2 - 0.0062 15.2 0.0 0.0096 14.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 CBK23621.2 - 0.013 14.5 0.1 0.083 11.9 0.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 CBK23621.2 - 0.083 12.1 0.5 0.54 9.5 0.2 2.3 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 CBK23621.2 - 0.1 12.9 0.1 0.38 11.0 0.0 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain La PF05383.12 CBK23622.2 - 7.7e-21 73.6 0.4 1.9e-20 72.4 0.3 1.7 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBK23622.2 - 6.1e-06 26.1 0.1 6.7e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK23622.2 - 9.5e-05 21.9 0.1 0.0003 20.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23622.2 - 0.14 12.0 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L3 PF00297.17 CBK23623.2 - 1.8e-114 381.5 8.0 2.2e-114 381.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 GST_N PF02798.15 CBK23624.2 - 5.6e-13 48.8 0.1 1.7e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBK23624.2 - 8.5e-10 38.5 0.2 1.2e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBK23624.2 - 3.1e-08 33.7 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBK23624.2 - 7e-06 26.4 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBK23624.2 - 2e-05 24.4 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBK23624.2 - 0.00071 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Toxin_61 PF15538.1 CBK23624.2 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 61 Exo_endo_phos_2 PF14529.1 CBK23625.2 - 4e-09 36.1 0.0 4.6e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CBK23625.2 - 2.1e-08 34.4 0.0 3.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_pol_Rpb4 PF03874.11 CBK23626.2 - 1.9e-10 40.7 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 CENP-B_N PF04218.8 CBK23626.2 - 0.1 11.9 0.0 0.48 9.8 0.0 2.1 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Clathrin PF00637.15 CBK23627.2 - 1.3e-16 60.4 11.5 1.2e-11 44.3 0.8 3.1 4 1 0 4 4 4 2 Region in Clathrin and VPS TPR_11 PF13414.1 CBK23627.2 - 0.0077 15.8 0.1 0.031 13.9 0.0 2.1 1 0 0 1 1 1 1 TPR repeat C1_1 PF00130.17 CBK23627.2 - 0.099 12.3 2.4 0.26 11.0 1.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_2 PF07719.12 CBK23627.2 - 0.15 12.0 0.2 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 CBK23627.2 - 0.41 10.7 5.6 1.5 8.9 3.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK23627.2 - 2.7 7.8 10.8 0.21 11.4 3.6 2.1 2 0 0 2 2 2 0 Ring finger domain Pyr_redox_2 PF07992.9 CBK23629.2 - 1.4e-33 116.4 0.0 1.8e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBK23629.2 - 3.2e-25 88.3 0.0 5.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBK23629.2 - 4.8e-16 58.9 0.6 2.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK23629.2 - 5.3e-11 42.9 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBK23629.2 - 9.6e-06 24.6 0.7 2.8e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CBK23629.2 - 0.00018 20.4 0.3 0.00029 19.8 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBK23629.2 - 0.00021 20.4 3.8 0.001 18.2 1.8 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.19 CBK23629.2 - 0.00034 19.6 0.9 0.077 11.8 0.6 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBK23629.2 - 0.00067 18.2 0.3 0.0041 15.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CBK23629.2 - 0.0019 17.3 0.1 0.0042 16.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CBK23629.2 - 0.017 15.1 2.9 0.2 11.7 0.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pribosyltran_N PF13793.1 CBK23630.2 - 1.5e-45 153.6 0.0 1.6e-44 150.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBK23630.2 - 4.6e-25 88.4 0.7 4.6e-25 88.4 0.5 1.6 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBK23630.2 - 3.5e-12 46.1 0.1 9.1e-12 44.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBK23630.2 - 0.0039 16.4 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HTH_31 PF13560.1 CBK23630.2 - 0.044 13.9 0.2 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Creatininase PF02633.9 CBK23630.2 - 0.085 11.9 0.0 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Creatinine amidohydrolase Gram_pos_anchor PF00746.16 CBK23630.2 - 0.19 11.5 1.0 0.4 10.5 0.7 1.4 1 0 0 1 1 1 0 Gram positive anchor Peptidase_M24 PF00557.19 CBK23631.2 - 9.9e-39 133.0 0.5 1.3e-38 132.6 0.3 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Shugoshin_N PF07558.6 CBK23632.2 - 0.67 9.7 6.3 0.15 11.7 0.4 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region AAA_13 PF13166.1 CBK23632.2 - 3.1 6.1 24.0 0.048 12.1 6.9 2.1 1 1 1 2 2 2 0 AAA domain MerR-DNA-bind PF09278.6 CBK23633.2 - 0.031 14.6 3.2 0.031 14.6 2.2 3.2 1 1 1 2 2 2 0 MerR, DNA binding DivIC PF04977.10 CBK23633.2 - 0.11 12.0 13.4 0.48 9.9 0.4 2.8 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.7 CBK23633.2 - 0.17 10.2 12.0 0.2 10.0 8.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 CBK23633.2 - 0.4 8.4 4.2 0.5 8.1 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 CBK23633.2 - 0.41 10.4 10.6 0.84 9.4 0.5 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.1 CBK23633.2 - 0.44 10.5 16.0 0.21 11.5 9.3 1.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.6 CBK23633.2 - 0.45 10.3 15.2 0.12 12.1 2.2 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 CBK23633.2 - 0.61 10.4 10.4 5.6 7.3 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 CBK23633.2 - 0.72 9.6 3.1 2.7 7.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 CBK23633.2 - 0.86 8.9 5.5 0.3 10.4 1.6 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4172 PF13776.1 CBK23633.2 - 0.88 9.7 3.6 4.8 7.3 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4172) DUF4618 PF15397.1 CBK23633.2 - 1.9 7.7 10.7 0.19 11.0 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 CBK23633.2 - 2.9 7.9 15.5 0.66 9.9 0.8 3.2 3 1 0 3 3 2 0 bZIP transcription factor Spc24 PF08286.6 CBK23633.2 - 3.7 7.2 10.7 4.3 7.0 2.2 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 CBK23633.2 - 4.5 7.1 16.8 2.8 7.7 10.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CBK23633.2 - 8.6 5.4 11.7 35 3.5 8.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 CBK23633.2 - 9.5 5.8 14.2 25 4.4 8.9 2.1 1 1 0 1 1 1 0 Mnd1 family RRM_1 PF00076.17 CBK23634.2 - 5.1e-40 134.9 0.1 1.6e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23634.2 - 2.9e-29 100.8 0.0 1.4e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23634.2 - 1.8e-12 46.9 0.4 4.5e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBK23634.2 - 7.7e-05 22.3 0.0 0.015 15.0 0.0 2.7 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBK23634.2 - 0.013 15.2 0.4 0.22 11.3 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.1 CBK23634.2 - 0.019 14.7 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3402 PF11882.3 CBK23634.2 - 0.045 12.8 2.2 0.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Cgr1 PF03879.9 CBK23635.2 - 0.16 12.1 30.8 0.09 12.9 19.7 1.8 1 1 0 1 1 1 0 Cgr1 family DUF2514 PF10721.4 CBK23635.2 - 0.33 10.6 7.7 0.61 9.7 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) CDC50 PF03381.10 CBK23635.2 - 0.5 9.4 7.3 1.1 8.3 4.6 1.7 1 1 1 2 2 2 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Rota_VP2 PF05087.7 CBK23635.2 - 3.9 5.2 13.9 5 4.9 9.6 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Atg14 PF10186.4 CBK23635.2 - 4.5 6.1 13.8 4.8 6.0 9.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GvpL_GvpF PF06386.6 CBK23635.2 - 5.2 6.5 9.1 8.3 5.9 6.3 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PGC7_Stella PF15549.1 CBK23635.2 - 8.4 6.3 16.7 2.2 8.2 8.7 1.8 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain DASH_Dad4 PF08650.5 CBK23636.2 - 1.8e-08 34.1 1.1 1.9e-08 34.0 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 CBK23636.2 - 0.00058 19.5 0.2 0.00073 19.1 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SNARE PF05739.14 CBK23636.2 - 0.02 14.5 0.7 0.029 14.0 0.5 1.4 1 0 0 1 1 1 0 SNARE domain DUF948 PF06103.6 CBK23636.2 - 0.083 12.7 0.1 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA PF00004.24 CBK23637.2 - 2e-32 112.1 0.0 3.9e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBK23637.2 - 1e-07 31.2 0.0 8e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBK23637.2 - 2.1e-05 25.3 0.2 0.00011 23.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK23637.2 - 6e-05 23.3 0.1 0.00071 19.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBK23637.2 - 0.0002 21.0 0.7 0.019 14.6 0.3 3.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK23637.2 - 0.00021 21.4 0.5 0.018 15.2 0.3 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK23637.2 - 0.00034 20.6 0.8 0.0032 17.4 0.2 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.1 CBK23637.2 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CBK23637.2 - 0.00063 19.6 0.1 0.0053 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBK23637.2 - 0.00078 19.3 0.0 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK23637.2 - 0.0034 17.1 0.0 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 CBK23637.2 - 0.0046 16.5 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBK23637.2 - 0.0073 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ResIII PF04851.10 CBK23637.2 - 0.0089 15.8 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 CBK23637.2 - 0.019 13.6 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 CBK23637.2 - 0.024 14.7 0.0 0.087 12.8 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CBK23637.2 - 0.035 13.5 0.0 0.69 9.3 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.7 CBK23637.2 - 0.04 13.5 0.9 4.8 6.8 0.0 3.3 4 0 0 4 4 4 0 NACHT domain HTH_38 PF13936.1 CBK23637.2 - 0.072 12.6 4.3 1.5 8.4 0.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Mg_chelatase PF01078.16 CBK23637.2 - 0.1 11.7 0.0 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Gar1 PF04410.9 CBK23638.2 - 1.6e-09 37.3 0.3 2e-09 37.1 0.2 1.3 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA_12 PF13087.1 CBK23639.2 - 2.7e-53 180.3 0.0 3.4e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK23639.2 - 2.1e-24 86.3 0.0 3.2e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CBK23639.2 - 8.3e-05 22.2 0.2 0.013 14.9 0.0 2.2 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase PRTase_1 PF11202.3 CBK23639.2 - 0.03 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) zf-CCCH PF00642.19 CBK23640.2 - 9.5e-12 44.3 15.6 1.1e-06 28.2 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CBK23640.2 - 4e-07 29.5 0.0 6.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23640.2 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23640.2 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK23640.2 - 0.032 14.0 0.1 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Scramblase PF03803.10 CBK23642.2 - 1.3e-08 34.2 0.0 1.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Scramblase PEPCK_ATP PF01293.15 CBK23646.2 - 7.1e-05 21.5 0.0 0.0002 20.0 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase Cupin_2 PF07883.6 CBK23646.2 - 0.17 11.4 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UCH PF00443.24 CBK23647.2 - 3.2e-39 134.6 0.1 4.2e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CBK23647.2 - 2.9e-09 37.2 0.7 9e-09 35.6 0.0 2.1 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.1 CBK23647.2 - 2.4e-06 27.2 2.1 3.6e-06 26.6 1.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.1 CBK23647.2 - 4.7e-06 26.1 0.5 9.3e-06 25.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.1 CBK23647.2 - 0.00075 19.7 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 CBK23647.2 - 0.13 11.7 0.4 0.61 9.5 0.3 2.0 1 1 0 1 1 1 0 Ubiquitin family WD40 PF00400.27 CBK23649.2 - 3.8e-84 273.8 17.8 3.4e-13 48.8 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CBK23649.2 - 7.9e-16 57.8 0.6 1.4e-15 56.9 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CBK23649.2 - 5.3e-09 36.0 0.0 0.00011 22.0 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBK23649.2 - 1.3e-08 33.4 3.8 0.017 13.2 0.0 4.5 3 2 2 5 5 5 4 Nucleoporin Nup120/160 PD40 PF07676.7 CBK23649.2 - 0.00088 18.8 1.2 23 4.7 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CBK23649.2 - 0.0014 17.7 0.3 0.52 9.3 0.0 3.7 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 CBK23649.2 - 0.015 14.6 1.3 10 5.5 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 CBK23649.2 - 0.022 13.4 0.0 0.45 9.1 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.7 CBK23649.2 - 0.036 11.8 0.0 0.31 8.8 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.11 CBK23649.2 - 0.037 12.3 0.1 0.98 7.6 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain Histone PF00125.19 CBK23650.2 - 1.4e-23 82.7 0.1 1.8e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK23650.2 - 1.8e-05 24.7 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFX_C PF14601.1 CBK23650.2 - 0.021 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Histone PF00125.19 CBK23651.2 - 7.5e-21 74.0 0.2 1.1e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK23651.2 - 2.8e-05 24.0 0.0 5.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NMT PF01233.14 CBK23652.2 - 4.3e-69 231.2 0.0 6.3e-69 230.7 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CBK23652.2 - 7.8e-64 214.5 0.2 1.3e-63 213.7 0.1 1.4 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CBK23652.2 - 2.5e-06 27.3 0.0 6.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK23652.2 - 0.0001 22.3 0.1 0.064 13.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Snf7 PF03357.16 CBK23653.2 - 9e-08 31.6 2.5 9e-08 31.6 1.7 2.1 1 1 1 2 2 2 1 Snf7 Baculo_PEP_C PF04513.7 CBK23653.2 - 0.0075 16.0 0.1 0.27 11.0 0.0 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GPO PF05929.6 CBK23653.2 - 0.014 14.6 1.2 0.058 12.6 0.0 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Wbp11 PF09429.5 CBK23653.2 - 0.02 14.8 2.5 0.066 13.2 0.0 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 DnaG_DnaB_bind PF08278.6 CBK23653.2 - 0.28 11.4 2.8 8.4 6.6 0.6 2.5 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Snapin_Pallidin PF14712.1 CBK23653.2 - 0.34 11.2 3.8 29 5.0 0.0 3.5 2 1 1 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.7 CBK23653.2 - 0.47 10.7 2.6 2.6 8.3 0.0 3.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlgN PF05130.7 CBK23653.2 - 0.9 9.7 6.8 0.47 10.6 2.0 2.2 2 1 0 2 2 2 0 FlgN protein Tweety PF04906.8 CBK23653.2 - 2.2 6.6 5.6 1.4 7.2 0.8 2.0 1 1 0 2 2 2 0 Tweety DUF16 PF01519.11 CBK23653.2 - 3.2 8.0 8.3 34 4.7 5.6 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 RE_MjaI PF09568.5 CBK23653.2 - 4 6.9 9.1 1.1 8.8 1.5 2.8 2 1 0 2 2 2 0 MjaI restriction endonuclease Metallophos PF00149.23 CBK23654.2 - 3.8e-31 108.0 0.1 4.9e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mpp10 PF04006.7 CBK23655.2 - 0.0022 16.4 0.0 0.0028 16.1 0.0 1.0 1 0 0 1 1 1 1 Mpp10 protein Rad51 PF08423.6 CBK23656.2 - 2.6e-129 429.6 0.1 3.1e-129 429.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK23656.2 - 3.8e-14 52.5 0.0 5.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK23656.2 - 1.6e-11 43.8 0.0 2.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBK23656.2 - 5e-10 39.4 0.1 1.1e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBK23656.2 - 1.4e-08 34.1 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 CBK23656.2 - 0.0025 16.7 0.0 0.0047 15.7 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein DnaB_C PF03796.10 CBK23656.2 - 0.0032 16.3 0.1 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA PF00004.24 CBK23656.2 - 0.0056 16.8 0.1 0.089 12.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK23656.2 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBK23656.2 - 0.053 13.4 0.3 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain GvpD PF07088.6 CBK23656.2 - 0.1 10.9 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein ubiquitin PF00240.18 CBK23657.2 - 1.1e-07 31.1 0.2 3.7e-07 29.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBK23657.2 - 1.7e-05 24.9 0.1 6.8e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CBK23657.2 - 0.029 14.0 0.1 0.15 11.7 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_S49_N PF08496.5 CBK23659.2 - 1.2 8.8 3.2 1.2 8.8 2.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 CBK23659.2 - 2.8 7.5 9.6 2.8 7.5 6.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DnaJ PF00226.26 CBK23660.2 - 2.6e-20 71.9 0.7 7.6e-20 70.4 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain JAB PF01398.16 CBK23661.2 - 1.9e-10 40.4 0.0 3.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0197 PF05251.7 CBK23662.2 - 4.3e-10 39.7 6.0 5.2e-10 39.4 4.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) SyrA PF11089.3 CBK23662.2 - 0.51 10.1 5.1 8 6.3 0.1 2.2 2 0 0 2 2 2 0 Exopolysaccharide production repressor Pkinase PF00069.20 CBK23664.2 - 4.5e-68 229.2 0.0 6.7e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23664.2 - 2.5e-49 167.6 0.0 3.4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23664.2 - 0.0047 15.9 0.0 0.022 13.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like NLE PF08154.7 CBK23666.2 - 1.1e-18 67.0 0.2 1.5e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain Peptidase_M3_N PF08439.5 CBK23666.2 - 0.29 11.2 2.7 7.7 6.6 0.1 2.1 2 0 0 2 2 2 0 Oligopeptidase F Memo PF01875.12 CBK23667.2 - 2.7e-39 134.7 0.0 3.1e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Gtr1_RagA PF04670.7 CBK23668.2 - 6e-25 87.7 0.5 7.1e-25 87.5 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1992 PF09350.5 CBK23668.2 - 0.0024 17.6 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RF-1 PF00472.15 CBK23669.2 - 2e-36 124.2 0.3 2.7e-36 123.8 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CBK23669.2 - 6.6e-05 22.5 0.4 0.00039 20.1 0.0 2.2 2 0 0 2 2 2 1 PCRF domain MAT_Alpha1 PF04769.7 CBK23669.2 - 0.091 12.0 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 SH3_2 PF07653.12 CBK23670.2 - 1.5e-06 27.5 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBK23670.2 - 2.6e-06 26.6 0.0 3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBK23670.2 - 3.6e-05 23.2 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain FAA_hydrolase PF01557.13 CBK23671.2 - 2.8e-55 187.1 0.0 3.1e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribosomal_S17 PF00366.15 CBK23672.2 - 3.1e-10 39.9 3.9 5e-10 39.2 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PMSI1 PF15322.1 CBK23672.2 - 0.0088 15.1 0.1 0.0088 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative Biotin_lipoyl PF00364.17 CBK23672.2 - 0.062 12.9 1.4 0.12 12.0 0.9 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF778 PF05608.7 CBK23673.2 - 7.7e-15 55.0 0.2 8.9e-08 32.1 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) MiAMP1 PF09117.5 CBK23673.2 - 0.057 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 MiAMP1 Fst_toxin PF13955.1 CBK23673.2 - 1.1 9.0 5.3 1.8 8.3 3.7 1.3 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system zf-CCHC PF00098.18 CBK23674.2 - 7.8e-12 44.5 39.9 7.6e-05 22.4 2.4 5.7 7 0 0 7 7 7 4 Zinc knuckle zf-CCHC_3 PF13917.1 CBK23674.2 - 3.4e-08 33.0 27.4 0.001 18.7 1.3 4.5 2 1 2 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 CBK23674.2 - 0.029 13.8 0.5 0.029 13.8 0.3 4.8 2 2 3 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBK23674.2 - 0.036 13.7 2.5 0.036 13.7 1.7 4.8 5 0 0 5 5 5 0 Zinc knuckle Peptidase_C5 PF00770.13 CBK23674.2 - 0.12 11.8 2.0 0.24 10.9 1.4 1.5 1 0 0 1 1 1 0 Adenovirus endoprotease zf-CCHC_6 PF15288.1 CBK23674.2 - 3 7.5 23.5 3.4 7.4 1.5 4.7 4 0 0 4 4 4 0 Zinc knuckle Myb_DNA-binding PF00249.26 CBK23675.2 - 0.023 14.7 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAPS_reduct PF01507.14 CBK23676.2 - 2.9e-22 79.3 0.0 7.9e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AAA_2 PF07724.9 CBK23677.2 - 1.6e-51 174.5 0.0 6.9e-50 169.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CBK23677.2 - 1.1e-23 82.8 0.0 2.8e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CBK23677.2 - 2.2e-23 82.8 0.0 1.4e-12 47.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK23677.2 - 1.8e-15 56.9 0.0 1e-10 41.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBK23677.2 - 6.3e-13 49.1 2.4 0.00011 22.2 0.0 4.8 4 1 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 CBK23677.2 - 4.2e-09 36.6 1.1 0.0089 16.1 0.0 4.4 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CBK23677.2 - 9e-08 31.7 0.0 9e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBK23677.2 - 2.2e-06 27.5 1.3 0.03 14.0 0.1 4.1 4 1 0 4 4 3 1 Archaeal ATPase AAA_17 PF13207.1 CBK23677.2 - 5.8e-06 27.1 0.1 0.016 16.0 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK23677.2 - 1.5e-05 24.8 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBK23677.2 - 3.1e-05 24.2 0.0 0.51 10.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBK23677.2 - 8e-05 21.7 0.3 0.24 10.4 0.0 3.2 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBK23677.2 - 0.00011 21.6 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CBK23677.2 - 0.00015 21.9 0.0 0.14 12.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_3 PF07726.6 CBK23677.2 - 0.00028 20.4 0.0 0.062 12.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBK23677.2 - 0.00073 18.9 0.1 1.8 7.9 0.0 3.1 2 2 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CBK23677.2 - 0.00093 18.4 0.0 1.8 7.6 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBK23677.2 - 0.0012 18.5 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 CBK23677.2 - 0.0013 18.4 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBK23677.2 - 0.004 17.0 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CBK23677.2 - 0.004 16.8 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DNA_pol3_delta2 PF13177.1 CBK23677.2 - 0.0047 16.6 0.0 0.16 11.6 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ABC_tran PF00005.22 CBK23677.2 - 0.006 16.8 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 CBK23677.2 - 0.006 16.1 0.1 0.47 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBK23677.2 - 0.0067 15.9 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 CBK23677.2 - 0.0082 15.8 0.1 3.2 7.4 0.0 2.9 3 0 0 3 3 2 1 NTPase Miro PF08477.8 CBK23677.2 - 0.0082 16.6 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 CBK23677.2 - 0.0098 15.3 0.2 12 5.2 0.0 3.6 3 2 1 4 4 4 0 AAA-like domain DUF258 PF03193.11 CBK23677.2 - 0.02 14.0 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBK23677.2 - 0.025 14.9 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 CBK23677.2 - 0.027 14.2 0.0 1 9.1 0.0 3.2 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit RHH_3 PF12651.2 CBK23677.2 - 0.028 14.1 0.1 1.8 8.3 0.0 3.2 3 0 0 3 3 3 0 Ribbon-helix-helix domain ATP_bind_1 PF03029.12 CBK23677.2 - 0.03 13.8 0.2 3.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 CBK23677.2 - 0.039 13.5 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CBK23677.2 - 0.054 12.3 0.0 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 CBK23677.2 - 0.058 13.3 1.5 21 5.0 0.0 3.6 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 CBK23677.2 - 0.11 12.3 0.1 9.2 6.0 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 PCI_Csn8 PF10075.4 CBK23677.2 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 GDPD PF03009.12 CBK23678.2 - 3.2e-40 138.2 0.0 8.4e-40 136.8 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Bromodomain PF00439.20 CBK23679.2 - 1.3e-09 37.7 0.1 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain SprT-like PF10263.4 CBK23680.2 - 2.6e-32 111.6 3.3 3.3e-32 111.3 2.3 1.1 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 CBK23680.2 - 0.0068 16.2 2.6 0.016 15.0 1.9 1.4 1 1 0 1 1 1 1 WLM domain TMEM18 PF14770.1 CBK23680.2 - 0.027 13.9 1.0 0.31 10.5 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 18 MFS_2 PF13347.1 CBK23680.2 - 0.055 11.8 0.0 0.055 11.8 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein ASFV_J13L PF05568.6 CBK23680.2 - 0.075 12.5 0.8 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_L20 PF00453.13 CBK23680.2 - 0.086 12.7 0.5 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L20 DUF2367 PF10164.4 CBK23680.2 - 0.1 12.4 0.5 0.25 11.1 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Vpu PF00558.14 CBK23680.2 - 0.52 9.9 2.9 0.61 9.6 1.0 1.8 2 0 0 2 2 2 0 Vpu protein DEAD PF00270.24 CBK23681.2 - 5.3e-41 139.9 0.0 7.7e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23681.2 - 3.6e-25 87.6 0.1 6.3e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bax1-I PF01027.15 CBK23682.2 - 2.2e-17 63.3 26.0 2.5e-17 63.1 18.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SH PF01445.12 CBK23682.2 - 4.4 7.0 7.0 5.9 6.6 3.3 2.3 2 0 0 2 2 2 0 Viral small hydrophobic protein Pkinase PF00069.20 CBK23684.2 - 3.3e-56 190.3 0.1 7.3e-56 189.2 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23684.2 - 2.7e-31 108.5 1.3 4.4e-23 81.6 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBK23684.2 - 0.0014 17.6 1.3 0.023 13.6 0.1 2.8 2 1 0 2 2 2 1 Kinase-like DUF148 PF02520.12 CBK23684.2 - 0.043 13.6 1.7 0.072 12.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Aminotran_1_2 PF00155.16 CBK23685.2 - 5.9e-48 163.6 0.0 7e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK23685.2 - 0.00019 20.6 0.0 0.00045 19.4 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Ldh_1_N PF00056.18 CBK23685.2 - 0.11 12.3 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Ribosomal_L30 PF00327.15 CBK23686.2 - 3.8e-21 74.4 1.3 3.8e-21 74.4 0.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Mon1 PF03164.9 CBK23687.2 - 1.4e-43 149.1 4.2 1.1e-38 133.0 3.1 1.9 2 0 0 2 2 2 2 Trafficking protein Mon1 Ribosomal_S7e PF01251.13 CBK23688.2 - 1.4e-55 187.6 0.7 1.7e-55 187.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SPC22 PF04573.7 CBK23689.2 - 3.1e-12 46.0 0.1 5.2e-12 45.3 0.1 1.3 1 1 0 1 1 1 1 Signal peptidase subunit TPR_1 PF00515.23 CBK23690.2 - 1.2e-15 56.3 7.1 0.0032 16.9 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23690.2 - 1.3e-15 57.6 10.7 4e-08 33.7 0.2 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBK23690.2 - 4.7e-15 54.2 13.7 0.0082 15.9 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBK23690.2 - 3e-14 52.4 12.0 2.2e-07 30.4 0.3 4.9 2 1 4 6 6 6 5 TPR repeat TPR_17 PF13431.1 CBK23690.2 - 2.5e-12 45.9 2.5 0.031 14.4 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23690.2 - 8.4e-10 38.4 12.9 0.005 17.3 0.1 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23690.2 - 4.8e-09 36.0 15.1 0.00021 21.1 0.5 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23690.2 - 4.7e-08 32.2 0.1 0.29 11.0 0.1 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23690.2 - 6.6e-08 32.7 11.5 0.00024 21.3 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBK23690.2 - 6.9e-07 28.5 4.8 1.1 9.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBK23690.2 - 1.3e-06 28.4 9.6 1.5 9.4 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK23690.2 - 1.8e-05 24.4 16.9 0.0033 17.2 2.2 4.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBK23690.2 - 0.0036 17.3 2.9 30 4.8 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBK23690.2 - 0.043 13.9 16.0 0.26 11.4 0.2 4.3 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CBK23690.2 - 0.13 12.0 7.7 1 9.2 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBK23690.2 - 0.38 10.7 13.2 7.5 6.6 0.3 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBK23690.2 - 2.6 8.7 13.8 9.8 6.9 0.8 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 CBK23691.2 - 4.6e-21 75.3 0.1 1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.18 CBK23691.2 - 0.00098 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family COPI_assoc PF08507.5 CBK23692.2 - 3.7e-15 55.8 14.8 4.9e-15 55.4 10.3 1.1 1 0 0 1 1 1 1 COPI associated protein TRP PF06011.7 CBK23692.2 - 0.0021 16.7 16.4 0.0037 15.9 11.4 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Herpes_LMP1 PF05297.6 CBK23692.2 - 0.14 11.0 3.2 0.16 10.8 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TerC PF03741.11 CBK23692.2 - 0.33 10.3 12.8 0.085 12.2 5.0 2.0 1 1 1 2 2 2 0 Integral membrane protein TerC family FA_desaturase PF00487.19 CBK23692.2 - 0.7 9.2 7.4 0.42 10.0 4.0 1.4 1 1 0 1 1 1 0 Fatty acid desaturase EmrE PF13536.1 CBK23692.2 - 0.7 10.1 15.4 0.16 12.1 7.3 1.9 1 1 1 2 2 2 0 Multidrug resistance efflux transporter NPCC PF08058.6 CBK23692.2 - 6.2 6.6 12.1 16 5.3 6.3 2.6 1 1 1 2 2 2 0 Nuclear pore complex component DUF3784 PF12650.2 CBK23692.2 - 9 6.3 20.3 0.34 10.8 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) MORN PF02493.15 CBK23693.2 - 1.2e-06 27.8 17.6 0.0001 21.7 0.2 3.6 4 0 0 4 4 4 2 MORN repeat HAD_2 PF13419.1 CBK23694.2 - 4.8e-10 39.9 0.0 6.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBK23694.2 - 0.0019 18.6 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBK23694.2 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 CBK23695.2 - 1.2e-27 95.3 4.8 7.7e-20 70.3 1.3 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBK23695.2 - 1e-17 62.9 4.0 6.6e-06 25.5 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK23695.2 - 1.4e-16 58.9 3.2 0.00011 21.8 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23695.2 - 2.2e-09 36.3 3.0 0.0037 16.9 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23695.2 - 7.8e-09 35.3 0.8 8.5e-05 22.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBK23695.2 - 1.7e-07 30.4 0.4 0.0073 16.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK23695.2 - 7.5e-06 25.7 0.3 0.0076 16.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23695.2 - 2.1e-05 24.7 0.0 3.1 8.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK23695.2 - 6.6e-05 22.9 2.7 0.00011 22.2 1.9 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBK23695.2 - 7.7e-05 22.9 0.0 0.072 13.4 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBK23695.2 - 0.00021 20.4 0.1 3 7.1 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_16 PF13432.1 CBK23695.2 - 0.00067 20.2 0.0 0.11 13.2 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBK23695.2 - 0.0015 18.3 0.1 0.14 12.0 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 CBK23695.2 - 0.0025 17.6 3.5 0.09 12.6 0.1 2.7 2 2 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CBK23695.2 - 0.015 15.6 0.2 10 6.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CBK23695.2 - 0.034 13.5 0.4 0.63 9.3 0.0 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 P53_C PF11619.3 CBK23695.2 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain BTAD PF03704.12 CBK23695.2 - 0.13 12.5 0.0 8 6.7 0.0 1.9 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Sec5 PF15469.1 CBK23695.2 - 0.13 11.9 0.4 3.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 YchF-GTPase_C PF06071.8 CBK23696.2 - 1.2e-28 98.6 0.4 2.4e-28 97.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBK23696.2 - 0.00046 20.1 0.1 0.0017 18.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CBK23696.2 - 0.037 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 TGS domain zf-CCHC PF00098.18 CBK23697.2 - 6.8e-33 111.0 46.5 7.9e-07 28.7 1.4 6.8 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 CBK23697.2 - 2.6e-06 27.0 37.1 0.12 12.1 0.5 6.2 3 1 3 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 CBK23697.2 - 1.8e-05 24.2 33.3 0.06 13.0 0.7 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 CBK23697.2 - 4.1 6.9 43.0 0.068 12.6 1.3 6.2 4 1 3 7 7 7 0 Zinc knuckle DUF2845 PF11006.3 CBK23697.2 - 4.9 7.0 14.4 0.36 10.6 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) Ras PF00071.17 CBK23698.2 - 9.9e-22 77.0 0.0 1.4e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK23698.2 - 4.2e-08 33.6 0.0 1.2e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBK23698.2 - 0.0017 18.5 0.0 0.0058 16.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBK23698.2 - 0.011 15.7 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Herpes_UL55 PF04537.7 CBK23698.2 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL55 protein NB-ARC PF00931.17 CBK23698.2 - 0.052 12.3 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CBK23698.2 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CBK23698.2 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Cytochrom_C_asm PF01578.15 CBK23698.2 - 0.075 12.5 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein ABC_tran PF00005.22 CBK23698.2 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 CBK23698.2 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBK23698.2 - 0.22 11.1 2.2 0.31 10.6 0.1 2.4 3 1 0 3 3 3 0 NACHT domain tRNA-synt_1 PF00133.17 CBK23699.2 - 4.7e-201 668.8 0.0 2.2e-200 666.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBK23699.2 - 9.1e-43 145.6 0.2 2.3e-42 144.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBK23699.2 - 9.4e-18 64.0 0.4 1.1e-07 30.8 0.0 4.3 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CBK23699.2 - 5.9e-14 51.7 0.1 1.1e-09 37.8 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CBK23699.2 - 0.0011 18.9 7.3 0.0011 18.9 5.0 2.6 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 CBK23699.2 - 0.04 13.0 0.0 0.27 10.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Jag_N PF14804.1 CBK23699.2 - 0.044 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Jag N-terminus IncA PF04156.9 CBK23699.2 - 0.82 9.2 3.3 1.7 8.2 2.3 1.5 1 0 0 1 1 1 0 IncA protein CYTH PF01928.16 CBK23700.2 - 6.2e-08 32.5 0.0 6.2e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 CYTH domain PHP PF02811.14 CBK23701.2 - 1.3e-05 25.0 0.1 2.1e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 PHP domain AP_endonuc_2 PF01261.19 CBK23701.2 - 0.027 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PHP_C PF13263.1 CBK23701.2 - 0.16 11.5 0.0 0.48 9.9 0.0 1.8 1 0 0 1 1 1 0 PHP-associated Cpn60_TCP1 PF00118.19 CBK23702.2 - 7.6e-138 460.1 6.6 8.6e-138 459.9 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_primase_S PF01896.14 CBK23703.2 - 1.4e-30 106.0 0.2 1.7e-30 105.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Rer1 PF03248.8 CBK23704.2 - 3.4e-57 192.8 12.3 4.1e-57 192.6 8.5 1.1 1 0 0 1 1 1 1 Rer1 family Ndc1_Nup PF09531.5 CBK23704.2 - 0.11 10.9 5.5 0.15 10.4 3.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ANF_receptor PF01094.23 CBK23705.2 - 2.8e-15 55.9 0.1 3.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF444 PF04285.7 CBK23705.2 - 0.01 14.5 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF444) DUF1825 PF08855.5 CBK23705.2 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) Na_H_Exchanger PF00999.16 CBK23706.2 - 2.6e-38 131.5 37.7 5.4e-38 130.4 26.1 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TGT PF01702.13 CBK23707.2 - 3.2e-86 288.4 0.0 4.3e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF3596 PF12167.3 CBK23707.2 - 0.042 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) IRK PF01007.15 CBK23708.2 - 9.5e-35 119.9 2.4 1.9e-33 115.6 1.7 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBK23708.2 - 0.054 13.2 6.6 0.098 12.3 4.6 1.5 1 0 0 1 1 1 0 Ion channel Skp1 PF01466.14 CBK23709.2 - 2.2e-32 110.9 0.6 3.9e-32 110.1 0.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CBK23709.2 - 1.4e-05 25.0 0.9 3e-05 24.0 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF2136 PF09907.4 CBK23709.2 - 0.12 12.5 0.1 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2136) DEAD PF00270.24 CBK23710.2 - 1.9e-19 69.8 0.0 2.5e-18 66.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23710.2 - 1.2e-16 60.3 0.0 2.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 CBK23710.2 - 1.5e-06 27.8 0.0 6.1e-06 25.8 0.0 2.2 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 CBK23710.2 - 7.1e-06 25.6 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 CBK23710.2 - 0.00013 21.8 0.0 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0029 PF01205.14 CBK23711.2 - 6.8e-32 109.4 0.0 9.2e-32 108.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 NodZ PF05830.6 CBK23712.2 - 1.1e-12 47.2 0.0 1.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) LepA_C PF06421.7 CBK23713.2 - 6.5e-38 128.9 0.6 1e-37 128.2 0.4 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 CBK23713.2 - 2.6e-34 118.2 0.1 3.9e-34 117.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBK23713.2 - 6e-14 51.6 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 CBK23713.2 - 7.7e-05 22.1 0.0 0.00027 20.3 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 CBK23713.2 - 0.00036 20.3 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II PduV-EutP PF10662.4 CBK23713.2 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBK23713.2 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 CBK23713.2 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF434 PF04256.7 CBK23713.2 - 0.13 11.6 0.1 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Patatin PF01734.17 CBK23714.2 - 3.2e-14 53.3 8.4 7.3e-13 48.9 5.8 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Complex1_LYR_2 PF13233.1 CBK23714.2 - 0.059 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like NanE PF04131.9 CBK23715.2 - 1.4e-61 206.7 0.6 2e-61 206.2 0.4 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ROK PF00480.15 CBK23715.2 - 1.3e-31 109.8 1.7 4.8e-28 98.1 0.9 2.6 2 1 0 2 2 2 2 ROK family IMPDH PF00478.20 CBK23715.2 - 4.9e-07 28.9 0.1 1.7e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CBK23715.2 - 1.4e-06 27.7 0.0 4.4e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CBK23715.2 - 1.5e-05 24.2 0.2 0.0011 18.0 0.0 2.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 CBK23715.2 - 0.00014 20.7 0.1 0.00068 18.5 0.0 1.9 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) NMO PF03060.10 CBK23715.2 - 0.00084 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 CBK23715.2 - 0.00098 18.4 0.1 0.0069 15.6 0.0 2.5 3 1 1 4 4 4 1 PcrB family Trp_syntA PF00290.15 CBK23715.2 - 0.008 14.7 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain IGPS PF00218.16 CBK23715.2 - 0.015 14.3 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 CBK23715.2 - 0.029 13.2 0.0 0.077 11.8 0.0 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Arf PF00025.16 CBK23716.2 - 2.9e-72 241.5 0.1 3.4e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBK23716.2 - 2.2e-12 46.5 0.0 2.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBK23716.2 - 4.6e-12 45.6 0.0 5.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK23716.2 - 9.2e-11 41.0 1.6 1.2e-07 30.7 0.3 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK23716.2 - 4e-08 32.6 0.0 5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK23716.2 - 5.8e-08 33.2 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK23716.2 - 2.4e-06 27.4 0.1 4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK23716.2 - 0.01 15.2 0.5 0.2 11.0 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBK23716.2 - 0.013 14.3 0.4 0.072 11.8 0.4 2.0 2 1 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 CBK23716.2 - 0.06 12.6 1.1 0.36 10.0 0.8 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4005 PF13178.1 CBK23717.2 - 7.3e-14 51.8 47.8 0.0085 16.3 5.3 8.1 1 1 6 7 7 7 7 Protein of unknown function (DUF4005) HSP70 PF00012.15 CBK23718.2 - 9.7e-99 330.9 0.8 1.2e-98 330.5 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23718.2 - 1.9e-10 39.8 0.4 4.1e-09 35.4 0.0 2.9 3 1 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 CBK23718.2 - 0.00014 21.5 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CBK23718.2 - 0.00015 21.5 1.0 5.6 6.8 0.0 4.8 3 2 0 3 3 3 2 Cell division protein FtsA UBN2 PF14223.1 CBK23718.2 - 0.053 13.3 0.2 0.16 11.7 0.2 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GARS_A PF01071.14 CBK23719.2 - 8.9e-77 257.0 0.0 1.6e-76 256.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 CBK23719.2 - 9.5e-42 142.5 0.3 2.3e-41 141.3 0.2 1.7 2 0 0 2 2 2 1 Formyl transferase GARS_N PF02844.10 CBK23719.2 - 3.2e-38 130.2 0.9 1e-36 125.4 0.1 2.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 CBK23719.2 - 1.8e-31 108.1 0.3 6.4e-31 106.3 0.2 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 CBK23719.2 - 2.1e-30 105.7 0.1 8.2e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CBK23719.2 - 1.9e-14 53.6 0.7 7.6e-14 51.7 0.5 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CBK23719.2 - 2.5e-12 46.9 0.0 9.1e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CBK23719.2 - 1.9e-05 24.0 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 CBK23719.2 - 7.1e-05 21.6 0.1 0.00018 20.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CBK23719.2 - 0.0011 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBK23719.2 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ubiquitin PF00240.18 CBK23719.2 - 0.16 11.3 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Imm13 PF15564.1 CBK23719.2 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 13 He_PIG PF05345.7 CBK23721.2 - 8.4e-16 57.7 30.9 4.3e-05 23.4 0.1 5.5 5 1 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK23721.2 - 0.00015 21.5 5.5 1.7 8.5 0.1 4.3 4 0 0 4 4 4 2 Immunoglobulin I-set domain PIRT PF15099.1 CBK23721.2 - 0.026 13.7 0.0 0.081 12.1 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family IncA PF04156.9 CBK23721.2 - 0.03 13.9 1.2 0.047 13.2 0.8 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK23721.2 - 0.049 13.6 14.5 0.4 10.7 0.1 5.2 5 0 0 5 5 5 0 Hormone receptor domain Mg_trans_NIPA PF05653.9 CBK23721.2 - 0.059 12.3 0.5 2.5 6.9 0.3 2.2 2 0 0 2 2 2 0 Magnesium transporter NIPA DUF4097 PF13349.1 CBK23721.2 - 0.45 10.0 3.9 0.31 10.5 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) PKD PF00801.15 CBK23721.2 - 0.65 9.7 0.0 0.65 9.7 0.0 3.5 5 0 0 5 5 5 0 PKD domain DUF3185 PF11381.3 CBK23721.2 - 6.1 6.6 10.4 17 5.2 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) hEGF PF12661.2 CBK23721.2 - 9.7 6.5 12.6 10 6.4 0.1 4.3 4 0 0 4 4 4 0 Human growth factor-like EGF PQ-loop PF04193.9 CBK23723.2 - 1.6e-23 82.0 14.2 3.2e-18 65.0 4.3 3.5 4 0 0 4 4 4 2 PQ loop repeat PAP2_C PF14360.1 CBK23723.2 - 0.009 16.2 2.7 0.009 16.2 1.9 2.9 2 2 1 3 3 3 1 PAP2 superfamily C-terminal DUF202 PF02656.10 CBK23723.2 - 1.5 9.1 8.4 6.7 7.0 1.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Tim17 PF02466.14 CBK23725.2 - 9.3e-10 38.6 0.1 1.2e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1212 PF06738.7 CBK23725.2 - 0.0043 16.5 0.1 0.0087 15.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF2648 PF10855.3 CBK23725.2 - 0.096 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) COX7a PF02238.10 CBK23725.2 - 0.11 12.2 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa DUF754 PF05449.6 CBK23725.2 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF754) GDI PF00996.13 CBK23726.2 - 9.4e-173 574.5 0.0 1.1e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CBK23726.2 - 0.00036 20.4 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.20 CBK23727.2 - 2e-46 158.2 0.0 2.3e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23727.2 - 3.3e-31 108.3 0.0 4.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK23727.2 - 0.021 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBK23727.2 - 0.035 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CBK23727.2 - 0.044 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pro_isomerase PF00160.16 CBK23729.2 - 5.8e-41 140.2 1.1 9.8e-41 139.5 0.7 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBK23729.2 - 9.3e-17 60.4 0.1 2.3e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23729.2 - 4.2e-12 45.8 0.0 1.1e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23729.2 - 2.5e-11 43.2 0.5 1.6e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.13 CBK23730.2 - 9.8e-123 409.4 0.4 1.1e-122 409.2 0.3 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Tubulin PF00091.20 CBK23731.2 - 6.2e-69 232.1 0.1 1.2e-68 231.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK23731.2 - 3.5e-43 146.6 0.4 6.5e-43 145.7 0.3 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBK23731.2 - 8.4e-05 22.6 0.0 0.00055 19.9 0.0 2.2 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain BolA PF01722.13 CBK23732.2 - 3.8e-12 45.9 0.0 7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein CTP_transf_2 PF01467.21 CBK23732.2 - 7.9e-09 35.7 0.0 1.7e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase Myb_DNA-binding PF00249.26 CBK23733.2 - 1.1e-12 47.7 0.2 1.8e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK23733.2 - 7.1e-08 32.4 0.3 1.2e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Thioredoxin PF00085.15 CBK23734.2 - 6.8e-65 215.2 0.3 9.3e-32 108.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CBK23734.2 - 3.5e-18 65.8 2.3 4.6e-09 36.4 0.1 3.4 3 2 0 3 3 3 2 Thioredoxin-like domain ERp29 PF07749.7 CBK23734.2 - 2.3e-15 57.0 2.3 5.5e-14 52.5 1.7 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 CBK23734.2 - 1.3e-14 53.9 0.1 5.3e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK23734.2 - 2.7e-14 53.0 0.5 3.3e-05 23.9 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBK23734.2 - 3.7e-11 42.7 1.2 0.00011 21.9 0.2 2.7 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CBK23734.2 - 4.6e-09 35.9 0.1 0.00059 19.4 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 CBK23734.2 - 1.3e-07 31.5 3.8 1.5e-05 24.9 0.1 3.9 3 1 0 3 3 3 1 Thioredoxin-like domain ERp29_N PF07912.8 CBK23734.2 - 2.3e-07 30.7 0.4 0.0043 16.9 0.0 2.3 1 1 1 2 2 2 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 CBK23734.2 - 0.00064 19.7 2.6 0.81 9.6 0.1 3.9 3 1 1 4 4 4 1 Thioredoxin HyaE PF07449.6 CBK23734.2 - 0.0027 17.5 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 CBK23734.2 - 0.0056 16.2 0.5 1.9 8.0 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Fer4_15 PF13459.1 CBK23734.2 - 0.007 16.9 1.3 3.8 8.1 0.0 2.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF2458 PF10454.4 CBK23734.2 - 0.0075 16.1 0.9 0.016 15.0 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Apolipoprotein PF01442.13 CBK23734.2 - 0.0085 15.6 0.6 0.015 14.8 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 CBK23734.2 - 0.024 14.4 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cas_APE2256 PF09651.5 CBK23734.2 - 0.027 14.1 0.4 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) DDE_Tnp_1_2 PF13586.1 CBK23734.2 - 0.032 14.4 0.0 9.7 6.4 0.0 2.9 2 0 0 2 2 2 0 Transposase DDE domain DUF445 PF04286.7 CBK23734.2 - 0.036 13.5 2.7 0.096 12.1 1.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF445) SQS_PSY PF00494.14 CBK23734.2 - 0.05 12.8 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF948 PF06103.6 CBK23734.2 - 0.055 13.3 0.1 0.055 13.3 0.1 2.0 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) DUF2017 PF09438.5 CBK23734.2 - 0.069 12.7 0.2 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) Glutaredoxin PF00462.19 CBK23734.2 - 0.086 12.8 7.0 5.1 7.1 0.9 3.6 2 2 0 2 2 2 0 Glutaredoxin Glyco_trans_1_2 PF13524.1 CBK23734.2 - 0.71 10.1 4.6 41 4.5 0.0 3.7 3 1 1 4 4 4 0 Glycosyl transferases group 1 Ribosom_S12_S23 PF00164.20 CBK23735.2 - 1.2e-37 128.0 1.7 1.5e-37 127.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PLDc_2 PF13091.1 CBK23736.2 - 0.00071 19.3 0.0 0.00093 18.9 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain RRM_1 PF00076.17 CBK23737.2 - 1.1e-09 37.8 0.8 2.7e-09 36.5 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23737.2 - 9.7e-06 25.4 0.1 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23737.2 - 0.0055 16.5 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK23737.2 - 0.0055 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CBK23737.2 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L18e PF00828.14 CBK23738.2 - 1.3e-31 109.5 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 CTP_transf_2 PF01467.21 CBK23739.2 - 2.9e-24 85.9 0.1 5.2e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Rsd_AlgQ PF04353.8 CBK23739.2 - 0.011 15.4 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Dimeth_Pyl PF09505.5 CBK23739.2 - 0.031 12.5 0.0 2.9 6.0 0.0 2.2 1 1 1 2 2 2 0 Dimethylamine methyltransferase (Dimeth_PyL) Kinesin PF00225.18 CBK23740.2 - 2.9e-94 315.4 0.0 2.9e-94 315.4 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain LPP PF04728.8 CBK23740.2 - 0.029 14.1 0.3 0.029 14.1 0.2 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3450 PF11932.3 CBK23740.2 - 1.1 8.5 21.7 0.18 11.0 1.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Speriolin_N PF15058.1 CBK23740.2 - 1.1 9.1 4.8 2.4 8.0 3.3 1.7 1 1 0 1 1 1 0 Speriolin N terminus DUF342 PF03961.8 CBK23740.2 - 1.2 7.4 13.7 1.9 6.7 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mago_nashi PF02792.9 CBK23741.2 - 4.6e-61 204.7 0.6 5.1e-61 204.5 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein SEA PF01390.15 CBK23742.2 - 0.04 13.5 0.5 0.09 12.4 0.3 1.5 1 0 0 1 1 1 0 SEA domain RPAP3_C PF13877.1 CBK23742.2 - 0.11 12.4 0.8 4.2 7.3 0.0 2.5 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Hexokinase_2 PF03727.11 CBK23743.2 - 7.5e-57 192.3 0.0 1e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CBK23743.2 - 1.1e-43 148.9 0.0 1.8e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase ArfGap PF01412.13 CBK23744.2 - 9.7e-25 86.6 0.3 1.5e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Acyltransferase PF01553.16 CBK23745.2 - 1.9e-05 24.0 0.1 0.00017 21.0 0.1 2.2 1 1 0 1 1 1 1 Acyltransferase Imm10 PF15562.1 CBK23745.2 - 0.054 13.2 1.6 0.1 12.3 1.1 1.5 1 0 0 1 1 1 0 Immunity protein 10 LRR_8 PF13855.1 CBK23746.2 - 0.0002 21.0 11.2 0.016 14.9 0.2 4.8 4 2 1 5 5 5 3 Leucine rich repeat hSac2 PF12456.3 CBK23746.2 - 0.086 12.2 0.1 4.8 6.6 0.0 3.1 2 1 1 3 3 3 0 Inositol phosphatase Metallophos PF00149.23 CBK23747.2 - 2.2e-41 141.4 0.2 3.2e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1712 PF08217.6 CBK23748.2 - 1.4e-11 43.3 2.0 3.7e-09 35.3 0.0 2.5 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) ODR4-like PF14778.1 CBK23748.2 - 0.0022 16.7 0.2 0.069 11.8 0.0 2.3 2 0 0 2 2 2 2 Olfactory receptor 4-like SLT_beta PF02258.11 CBK23748.2 - 0.093 12.5 0.3 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Shiga-like toxin beta subunit FPL PF09758.4 CBK23749.2 - 8.4e-36 122.9 5.6 4.1e-35 120.7 3.9 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein UME PF08064.8 CBK23749.2 - 0.0016 18.3 0.5 0.003 17.4 0.3 1.4 1 0 0 1 1 1 1 UME (NUC010) domain Nup188 PF10487.4 CBK23749.2 - 0.014 13.3 0.2 0.014 13.3 0.2 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 ATP-synt_A PF00119.15 CBK23749.2 - 0.035 13.5 0.2 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 ATP synthase A chain RAI16-like PF10257.4 CBK23749.2 - 0.062 12.2 0.2 0.094 11.6 0.1 1.4 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein He_PIG PF05345.7 CBK23750.2 - 4.6e-15 55.3 30.5 0.00031 20.6 3.0 5.5 4 2 0 5 5 5 4 Putative Ig domain I-set PF07679.11 CBK23750.2 - 2.4e-05 24.0 4.8 1.8 8.4 0.0 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.17 CBK23750.2 - 9.2e-05 22.3 8.6 0.33 10.9 0.1 4.6 4 0 0 4 4 4 2 Hormone receptor domain DUF59 PF01883.14 CBK23750.2 - 0.026 14.4 0.8 1.7 8.6 0.1 3.7 4 1 0 4 4 4 0 Domain of unknown function DUF59 hEGF PF12661.2 CBK23750.2 - 0.35 11.0 7.3 9 6.6 0.1 3.7 3 0 0 3 3 3 0 Human growth factor-like EGF Asp_protease PF09668.5 CBK23751.2 - 9.8e-13 47.7 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CBK23751.2 - 2.2e-09 36.5 0.0 3.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.1 CBK23751.2 - 2.2e-08 34.4 0.1 4.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CBK23751.2 - 1e-05 25.2 0.1 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 CBK23751.2 - 9e-05 22.0 0.3 0.0005 19.7 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 CBK23751.2 - 0.00015 21.5 0.1 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease dsDNA_bind PF01984.15 CBK23753.2 - 3e-22 78.6 4.9 4e-22 78.2 3.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Flu_M2 PF00599.12 CBK23753.2 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M2) DUF4094 PF13334.1 CBK23753.2 - 2 8.8 4.5 1.7 9.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) RCC1 PF00415.13 CBK23754.2 - 1.4e-38 130.8 10.5 2e-14 53.5 0.1 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBK23754.2 - 5.7e-24 83.1 22.2 5.3e-06 25.9 0.1 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.18 CBK23755.2 - 2.5e-11 43.8 0.0 4.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK23755.2 - 0.0016 18.6 0.6 0.003 17.7 0.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) MFS_1 PF07690.11 CBK23756.2 - 1.2e-22 80.1 27.2 7.8e-22 77.4 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CBK23756.2 - 0.0004 20.3 0.4 0.001 19.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) BT1 PF03092.11 CBK23756.2 - 0.025 13.2 8.8 0.17 10.5 1.9 3.0 3 0 0 3 3 3 0 BT1 family zf-C2H2 PF00096.21 CBK23757.2 - 1.5e-10 40.7 12.8 6.5e-06 26.1 2.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type HMG_box_2 PF09011.5 CBK23757.2 - 1.5e-09 38.0 0.6 3e-09 37.1 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBK23757.2 - 2.7e-08 33.9 0.6 5.2e-08 33.0 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box zf-C2H2_4 PF13894.1 CBK23757.2 - 8.6e-06 25.7 10.9 0.0061 16.8 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK23757.2 - 0.0002 21.4 15.0 0.0042 17.3 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 CBK23757.2 - 0.012 15.7 6.5 0.054 13.6 4.5 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CBK23757.2 - 0.029 14.5 10.1 0.98 9.7 0.9 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBK23757.2 - 0.91 9.7 13.6 1.8 8.8 1.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CBK23757.2 - 3.6 8.0 9.7 8.1 6.9 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 CBK23757.2 - 4 7.2 8.8 0.36 10.6 1.7 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 CBK23757.2 - 4 7.6 10.2 11 6.1 1.8 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Syntaxin-6_N PF09177.6 CBK23759.2 - 0.01 16.2 0.3 0.025 14.9 0.1 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.10 CBK23759.2 - 0.049 13.1 0.3 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.6 CBK23759.2 - 0.058 13.7 4.2 0.13 12.6 2.9 1.7 1 0 0 1 1 1 0 MerR, DNA binding DUF2205 PF10224.4 CBK23759.2 - 0.059 12.9 1.2 0.11 12.1 0.2 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3618 PF12277.3 CBK23759.2 - 0.069 13.1 3.7 0.15 12.1 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF1049 PF06305.6 CBK23759.2 - 0.097 12.1 2.4 0.18 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) GED PF02212.13 CBK23759.2 - 0.11 12.4 0.3 0.92 9.4 0.2 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain RbsD_FucU PF05025.8 CBK23760.2 - 2.1e-21 76.7 0.0 2.3e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family PHD PF00628.24 CBK23761.2 - 1.9e-07 30.6 5.0 1.9e-07 30.6 3.4 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CBK23761.2 - 5.9e-05 22.2 3.7 5.9e-05 22.2 2.6 2.5 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBK23761.2 - 0.0004 20.3 3.5 0.0019 18.1 0.0 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 CBK23761.2 - 0.018 14.7 4.5 0.018 14.7 3.2 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Myb_DNA-bind_6 PF13921.1 CBK23761.2 - 0.075 13.1 0.8 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain PHD PF00628.24 CBK23762.2 - 2.1e-07 30.4 9.1 2.1e-07 30.4 6.3 2.6 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 CBK23762.2 - 0.012 15.2 17.4 0.012 15.2 3.6 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1033 PF06279.6 CBK23762.2 - 2.9 7.7 5.8 67 3.3 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) Zn-ribbon_8 PF09723.5 CBK23762.2 - 9.9 6.2 16.3 2.8 7.9 0.3 3.7 3 1 1 4 4 4 0 Zinc ribbon domain DUF1049 PF06305.6 CBK23763.2 - 4.9 6.6 5.3 3.6 7.1 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 CBK23764.2 - 3.2e-45 154.3 0.0 4.9e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23764.2 - 1.6e-17 63.4 0.0 2.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK23764.2 - 1e-06 28.7 0.0 2.3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBK23764.2 - 0.012 14.6 0.3 0.031 13.3 0.1 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK23764.2 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF814 PF05670.8 CBK23765.2 - 1.1e-21 76.4 0.0 4.4e-20 71.3 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 CBK23765.2 - 2.2e-19 69.0 0.0 2.2e-19 69.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) zf-CCHC PF00098.18 CBK23765.2 - 0.077 12.9 0.7 0.16 11.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBK23765.2 - 0.13 11.9 1.0 0.31 10.7 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF572 PF04502.8 CBK23765.2 - 7.6 5.6 25.1 0.7 9.0 2.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) FbpA PF05833.6 CBK23766.2 - 5.3e-32 110.9 0.1 5.8e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Fe_hyd_lg_C PF02906.9 CBK23766.2 - 0.15 11.2 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain PHD PF00628.24 CBK23767.2 - 4.9e-10 38.9 10.3 6.5e-10 38.5 7.2 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK23767.2 - 0.00015 20.9 3.2 0.00015 20.9 2.2 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 CBK23767.2 - 0.066 13.3 7.3 0.1 12.7 5.1 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 CBK23767.2 - 0.12 11.6 5.7 0.039 13.2 2.2 1.5 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.1 CBK23767.2 - 0.14 12.1 6.4 0.18 11.7 4.4 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 CBK23767.2 - 1.3 8.9 11.1 2.2 8.1 7.7 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.1 CBK23767.2 - 7.4 6.3 11.3 2.5 7.9 4.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 HMG_box_2 PF09011.5 CBK23768.2 - 3.3e-07 30.5 5.8 6.9e-07 29.5 4.0 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBK23768.2 - 1.1e-06 28.7 8.8 3.4e-06 27.2 6.1 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_5 PF14887.1 CBK23768.2 - 0.015 15.1 1.5 0.027 14.2 1.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 zf-C2H2 PF00096.21 CBK23769.2 - 1.5e-09 37.5 11.7 0.0003 20.9 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK23769.2 - 3.6e-09 36.2 8.3 0.00084 19.5 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBK23769.2 - 1.7e-08 34.3 17.1 0.00051 20.2 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 CBK23769.2 - 3.2e-05 23.9 3.6 0.0016 18.4 0.6 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CBK23769.2 - 0.0044 17.1 12.3 0.82 9.8 1.3 4.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBK23769.2 - 0.08 12.8 9.6 0.088 12.7 0.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger Ribosomal_L37ae PF01780.14 CBK23769.2 - 0.4 10.5 3.6 15 5.5 0.1 2.5 1 1 1 2 2 2 0 Ribosomal L37ae protein family DNA_RNApol_7kD PF03604.8 CBK23769.2 - 1.9 7.9 4.7 1.5 8.3 0.2 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 CBK23769.2 - 2.8 7.9 6.1 3.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain HSP70 PF00012.15 CBK23772.2 - 1.3e-82 277.7 0.1 1.6e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK23772.2 - 2e-10 39.7 0.3 9.1e-06 24.4 0.0 2.7 3 0 0 3 3 3 2 MreB/Mbl protein Actin PF00022.14 CBK23772.2 - 0.00018 20.0 0.2 0.0097 14.3 0.2 2.1 1 1 0 1 1 1 1 Actin Hydantoinase_A PF01968.13 CBK23772.2 - 0.0049 15.9 0.6 1.3 8.0 0.0 2.8 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase StbA PF06406.6 CBK23772.2 - 0.017 14.0 0.0 0.18 10.7 0.0 2.2 2 0 0 2 2 2 0 StbA protein DDR PF08841.5 CBK23772.2 - 0.1 11.4 0.1 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CBK23772.2 - 0.12 12.1 1.1 43 3.9 0.0 3.7 4 0 0 4 4 4 0 Cell division protein FtsA RRM_6 PF14259.1 CBK23773.2 - 3.2e-12 46.2 0.0 6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK23773.2 - 1.2e-11 44.0 0.0 2.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23773.2 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK23773.2 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif NIPSNAP PF07978.8 CBK23773.2 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP DUF4651 PF15513.1 CBK23773.2 - 0.13 11.6 0.8 17 4.9 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4651) A2M_comp PF07678.9 CBK23774.2 - 5.9e-08 32.2 0.0 9.2e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin complement component A2M_recep PF07677.9 CBK23774.2 - 1.1e-06 28.7 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 A-macroglobulin receptor Thiol-ester_cl PF10569.4 CBK23774.2 - 5.6e-06 25.4 0.1 1.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Alpha-macro-globulin thiol-ester bond-forming region A2M_N PF01835.14 CBK23774.2 - 0.0039 17.3 0.0 0.072 13.3 0.0 2.8 2 0 0 2 2 2 1 MG2 domain Arrestin_C PF02752.17 CBK23774.2 - 0.024 14.7 0.1 0.41 10.7 0.1 2.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain PIN_4 PF13638.1 CBK23774.2 - 0.048 13.7 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 PIN domain EF-hand_4 PF12763.2 CBK23775.2 - 3.2e-11 42.8 0.1 9.4e-11 41.3 0.0 1.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBK23775.2 - 1.5e-08 33.3 0.1 0.0017 17.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CBK23775.2 - 5.1e-08 32.9 0.7 3e-07 30.4 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBK23775.2 - 1.8e-06 27.3 0.3 0.067 13.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBK23775.2 - 0.00042 19.5 0.8 5.5 6.5 0.0 4.1 3 1 1 4 4 4 2 EF hand Laminin_II PF06009.7 CBK23775.2 - 0.0018 18.0 2.2 0.0026 17.5 1.5 1.2 1 0 0 1 1 1 1 Laminin Domain II GAS PF13851.1 CBK23775.2 - 0.02 14.1 6.1 0.03 13.5 4.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBK23775.2 - 0.024 14.2 4.9 0.035 13.7 3.4 1.2 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 CBK23775.2 - 0.033 12.8 6.9 0.044 12.4 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EF-hand_8 PF13833.1 CBK23775.2 - 0.063 12.9 0.0 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair APG6 PF04111.7 CBK23775.2 - 0.2 10.6 5.7 0.27 10.2 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 CBK23775.2 - 0.58 10.6 7.3 0.52 10.7 2.8 2.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PHD PF00628.24 CBK23776.2 - 3.8e-10 39.3 2.7 7.3e-10 38.3 1.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK23776.2 - 0.0013 18.0 0.6 0.0027 16.9 0.4 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBK23776.2 - 0.013 15.6 2.0 0.015 15.4 0.2 2.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain GlnD_UR_UTase PF08335.6 CBK23777.2 - 0.12 12.2 1.8 0.13 12.1 1.3 1.1 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Cyclin_N PF00134.18 CBK23777.2 - 0.38 10.3 5.4 0.48 9.9 3.7 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain SR-25 PF10500.4 CBK23777.2 - 0.48 9.8 13.9 0.49 9.8 9.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NST1 PF13945.1 CBK23777.2 - 1.4 8.9 14.8 1.7 8.6 10.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Rtf2 PF04641.7 CBK23777.2 - 1.5 7.9 13.3 1.5 7.9 9.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RloB PF13707.1 CBK23777.2 - 3 7.4 8.4 3.4 7.2 5.8 1.1 1 0 0 1 1 1 0 RloB-like protein Protocadherin PF08374.6 CBK23777.2 - 3.1 7.3 8.7 3.5 7.2 6.0 1.2 1 0 0 1 1 1 0 Protocadherin RNA_pol_Rpb1_5 PF04998.12 CBK23777.2 - 8.9 5.4 10.0 9.1 5.4 6.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Ribosomal_S26e PF01283.14 CBK23778.2 - 4.5e-48 162.2 9.8 4.7e-48 162.1 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 CBK23778.2 - 0.00039 20.7 1.1 0.015 15.6 0.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP19 PF01922.12 CBK23778.2 - 0.0073 16.8 0.4 0.01 16.4 0.3 1.3 1 0 0 1 1 1 1 SRP19 protein Fer4_10 PF13237.1 CBK23778.2 - 0.014 15.1 0.6 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK23778.2 - 0.018 14.8 3.0 0.061 13.2 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain RNA_pol_N PF01194.12 CBK23778.2 - 0.03 14.3 1.8 0.065 13.2 1.3 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.4 CBK23778.2 - 0.039 13.0 0.7 0.088 11.8 0.5 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Fer4_19 PF06902.6 CBK23778.2 - 0.063 13.1 0.3 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 CBK23778.2 - 0.074 12.6 3.5 0.089 12.4 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Zn_ribbon_2 PF12674.2 CBK23778.2 - 0.1 12.9 0.1 11 6.4 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_2 PF12797.2 CBK23778.2 - 0.38 10.7 4.1 0.5 10.3 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 CBK23778.2 - 0.54 10.3 4.1 2.1 8.4 1.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK23778.2 - 0.92 9.8 5.4 2 8.7 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK23778.2 - 5.5 7.5 8.5 1.9 9.0 2.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain EGF_2 PF07974.8 CBK23779.2 - 0.00018 21.5 5.4 0.00018 21.5 3.8 2.9 2 1 1 3 3 3 1 EGF-like domain DUF3404 PF11884.3 CBK23779.2 - 0.017 14.0 1.1 0.04 12.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3404) DUF3139 PF11337.3 CBK23779.2 - 0.17 12.1 4.9 1.6 9.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) PHD PF00628.24 CBK23780.2 - 4.3e-09 35.9 12.6 1e-08 34.6 8.8 1.7 1 0 0 1 1 1 1 PHD-finger SAP30_Sin3_bdg PF13867.1 CBK23780.2 - 6.7e-07 29.0 0.5 3.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-HC5HC2H PF13771.1 CBK23780.2 - 0.14 12.2 9.7 0.23 11.6 6.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.1 CBK23780.2 - 0.23 11.1 5.5 0.42 10.3 3.8 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.7 CBK23780.2 - 0.26 11.0 4.8 1.8 8.4 0.6 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING-like PF08746.6 CBK23780.2 - 8.5 6.4 11.4 12 5.9 6.9 2.0 1 1 0 1 1 1 0 RING-like domain ABC_tran PF00005.22 CBK23781.2 - 4.9e-16 59.2 0.0 7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBK23781.2 - 6e-06 25.6 0.0 7.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK23781.2 - 6.4e-05 23.0 0.0 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 CBK23781.2 - 0.017 13.7 0.0 0.031 12.8 0.0 1.3 1 1 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CBK23781.2 - 0.042 13.7 0.1 0.38 10.7 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Thioredoxin PF00085.15 CBK23782.2 - 1.1e-21 76.4 0.1 1.3e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBK23782.2 - 9e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK23782.2 - 1.8e-05 24.7 0.1 3.9e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK23782.2 - 8.2e-05 22.7 0.1 0.00032 20.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBK23782.2 - 0.00094 18.8 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CBK23782.2 - 0.016 14.7 0.1 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredox_DsbH PF03190.10 CBK23782.2 - 0.023 14.3 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_3 PF13192.1 CBK23782.2 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.19 CBK23782.2 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin NMD3 PF04981.8 CBK23783.2 - 1.4e-42 145.4 4.1 1.4e-42 145.4 2.9 1.8 2 0 0 2 2 2 1 NMD3 family Yippee-Mis18 PF03226.9 CBK23783.2 - 0.059 13.4 0.1 0.49 10.4 0.1 2.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF164 PF02591.10 CBK23783.2 - 0.4 10.5 3.9 0.58 10.0 0.4 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain Pox_Ag35 PF03286.9 CBK23783.2 - 0.48 9.9 16.3 0.85 9.1 11.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DZR PF12773.2 CBK23783.2 - 2.1 8.2 5.3 37 4.2 3.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF1510 PF07423.6 CBK23783.2 - 4.6 6.5 20.8 1.3 8.2 12.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DNA_pol_B_2 PF03175.8 CBK23784.2 - 4.7e-09 35.4 10.5 0.0013 17.5 0.2 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral GHMP_kinases_C PF08544.8 CBK23786.2 - 1e-08 35.2 0.1 2.4e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 GHMP kinases C terminal CSTF2_hinge PF14327.1 CBK23786.2 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3215 PF11503.3 CBK23786.2 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) eIF3_N PF09440.5 CBK23787.2 - 1.5e-11 44.5 0.2 5.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain Rib_5-P_isom_A PF06026.9 CBK23789.2 - 2.5e-59 199.4 0.3 3e-59 199.2 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CBK23789.2 - 0.0016 18.1 0.2 0.0049 16.5 0.0 1.8 2 0 0 2 2 2 1 DeoR C terminal sensor domain TIM PF00121.13 CBK23790.2 - 6e-84 280.9 0.2 6e-84 280.9 0.1 1.5 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_C PF02800.15 CBK23790.2 - 1.7e-69 232.2 0.0 5.9e-69 230.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBK23790.2 - 5.9e-56 188.6 0.1 1.4e-55 187.3 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.9 CBK23790.2 - 0.035 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family SRPRB PF09439.5 CBK23791.2 - 6.7e-27 93.8 0.0 8.7e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBK23791.2 - 5.2e-09 35.5 0.0 7.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK23791.2 - 3.1e-06 26.4 0.0 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK23791.2 - 0.00012 22.5 0.0 0.00027 21.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CBK23791.2 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBK23791.2 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK23791.2 - 0.02 13.6 0.1 3.9 6.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 CBK23791.2 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain SET PF00856.23 CBK23792.2 - 9.3e-05 22.7 0.0 0.32 11.3 0.0 3.1 2 1 0 2 2 2 2 SET domain Rubis-subs-bind PF09273.6 CBK23792.2 - 0.0012 18.7 0.9 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF3658 PF12395.3 CBK23792.2 - 0.0041 16.6 0.2 0.31 10.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function DEAD PF00270.24 CBK23793.2 - 1.9e-28 99.0 0.1 2.7e-24 85.5 0.0 3.9 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23793.2 - 3.1e-24 84.6 0.0 7.5e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBK23793.2 - 0.0066 14.9 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DBP10CT PF08147.7 CBK23795.2 - 6.8e-15 54.6 4.1 1.6e-14 53.4 2.8 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain PAD_porph PF04371.10 CBK23796.2 - 2e-134 447.7 0.0 2.3e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 CBK23796.2 - 0.054 12.5 0.0 13 4.7 0.0 3.0 3 0 0 3 3 3 0 Amidinotransferase Helicase_C_2 PF13307.1 CBK23797.2 - 1.2e-36 126.1 0.0 1.7e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBK23798.2 - 2.9e-20 72.3 0.0 4.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 DUF483 PF04467.7 CBK23798.2 - 0.07 13.2 0.1 2.7 8.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF483) DEAD_2 PF06733.10 CBK23799.2 - 3.5e-09 36.2 3.0 3.5e-09 36.2 2.1 1.7 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 CBK23799.2 - 1.9e-07 31.0 0.0 2.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK23799.2 - 0.00033 20.1 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CBK23799.2 - 0.0015 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Herpes_U44 PF04533.8 CBK23799.2 - 0.018 14.2 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Herpes virus U44 protein T2SE PF00437.15 CBK23799.2 - 0.044 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3128 PF11326.3 CBK23799.2 - 0.061 13.4 0.5 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) SNF2_N PF00176.18 CBK23799.2 - 0.11 11.2 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DAGK_acc PF00609.14 CBK23800.2 - 2.1e-25 89.7 0.0 2.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Leo1 PF04004.8 CBK23801.2 - 5e-18 65.3 1.2 8.7e-18 64.6 0.9 1.4 1 0 0 1 1 1 1 Leo1-like protein Ank_2 PF12796.2 CBK23802.2 - 2.8e-14 53.2 1.6 1.5e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBK23802.2 - 1.3e-12 47.8 1.2 3e-07 30.7 0.0 4.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBK23802.2 - 1.3e-11 43.5 2.7 0.044 14.0 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 CBK23802.2 - 3.8e-09 35.8 6.2 0.11 12.3 0.3 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBK23802.2 - 0.00068 19.7 3.2 0.0073 16.5 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) UBA PF00627.26 CBK23802.2 - 0.055 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain DNA_pol_B_2 PF03175.8 CBK23803.2 - 8.7e-10 37.8 8.5 0.0019 16.9 0.1 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral MyTH4 PF00784.12 CBK23804.2 - 2.5e-10 40.3 0.4 6.6e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 CBK23804.2 - 5.5e-06 26.1 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 WW domain RA PF00788.18 CBK23804.2 - 0.00011 22.6 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IRS PF02174.12 CBK23804.2 - 0.008 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) FERM_M PF00373.13 CBK23804.2 - 0.036 14.2 0.8 0.57 10.3 0.6 2.6 1 1 0 1 1 1 0 FERM central domain DUF2668 PF10873.3 CBK23805.2 - 0.079 13.1 1.6 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) DUF1179 PF06678.6 CBK23805.2 - 0.41 10.9 1.9 2.1 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Aa_trans PF01490.13 CBK23806.2 - 5.2e-06 25.2 2.7 5.6e-06 25.0 1.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2700 PF10912.3 CBK23806.2 - 0.022 14.7 1.6 0.026 14.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) Cytochrom_B_C PF00032.12 CBK23806.2 - 0.023 14.9 1.6 0.028 14.6 1.1 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD CcmB PF03379.8 CBK23806.2 - 0.031 13.4 1.2 0.035 13.3 0.8 1.2 1 0 0 1 1 1 0 CcmB protein DUF3989 PF13150.1 CBK23806.2 - 0.25 10.7 1.0 0.49 9.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) DUF3270 PF11674.3 CBK23806.2 - 3.4 7.7 5.3 1.1 9.3 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3270) Peptidase_M41 PF01434.13 CBK23808.2 - 4.1e-62 209.4 0.2 8.6e-62 208.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBK23808.2 - 1.4e-40 138.5 0.0 5.1e-40 136.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M16_C PF05193.16 CBK23808.2 - 8.4e-12 45.1 0.1 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBK23808.2 - 5.7e-08 32.6 0.0 2.2e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) AAA_17 PF13207.1 CBK23808.2 - 4.8e-05 24.1 2.7 0.00024 21.9 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CBK23808.2 - 0.00058 19.5 0.0 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBK23808.2 - 0.0014 18.3 0.3 0.0034 17.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBK23808.2 - 0.0021 18.1 0.1 0.063 13.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBK23808.2 - 0.0045 16.1 0.2 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 CBK23808.2 - 0.0068 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK23808.2 - 0.011 15.7 0.0 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.9 CBK23808.2 - 0.029 14.2 0.0 0.029 14.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CBK23808.2 - 0.031 13.3 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBK23808.2 - 0.04 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CBK23808.2 - 0.23 10.8 2.5 1.3 8.3 0.5 2.7 2 1 1 3 3 3 0 AAA domain Pox_Ag35 PF03286.9 CBK23808.2 - 0.28 10.7 12.4 0.52 9.7 8.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AAA_18 PF13238.1 CBK23808.2 - 0.52 10.6 0.0 0.52 10.6 0.0 4.0 4 1 0 4 4 4 0 AAA domain AAA_11 PF13086.1 CBK23808.2 - 0.92 9.0 6.2 14 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pantoate_transf PF02548.10 CBK23810.2 - 3.6e-101 337.6 0.0 5.2e-101 337.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase NanE PF04131.9 CBK23810.2 - 0.0017 17.3 0.0 0.06 12.3 0.0 2.4 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase ETC_C1_NDUFA4 PF04800.7 CBK23811.2 - 2.1e-06 27.5 0.0 3.3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 ETC complex I subunit conserved region RCC1 PF00415.13 CBK23812.2 - 2.1e-36 123.8 1.6 1e-13 51.2 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.13 CBK23812.2 - 2.9e-36 124.9 0.0 6.5e-36 123.8 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RCC1_2 PF13540.1 CBK23812.2 - 5.4e-26 89.5 20.0 5.2e-09 35.4 0.5 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Oxidored_q1 PF00361.15 CBK23813.2 - 4.5e-69 232.7 35.9 4.5e-69 232.7 24.9 3.2 1 1 2 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q5_N PF01059.12 CBK23813.2 - 0.0028 17.5 22.7 0.0028 17.5 15.7 5.9 4 1 0 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus Complex1_49kDa PF00346.14 CBK23814.2 - 4.8e-115 383.2 0.1 6e-115 382.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DASH_Dad4 PF08650.5 CBK23814.2 - 0.12 12.3 0.1 0.39 10.6 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 Oxidored_q3 PF00499.15 CBK23815.2 - 3e-21 75.6 41.7 3.8e-21 75.3 28.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oxidored_q4 PF00507.14 CBK23816.2 - 7.7e-31 105.9 12.5 1.1e-30 105.4 8.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SUR7 PF06687.7 CBK23816.2 - 0.1 12.1 6.0 0.16 11.5 4.1 1.3 1 1 0 1 1 1 0 SUR7/PalI family Sulfate_transp PF00916.15 CBK23816.2 - 0.1 11.5 2.8 0.18 10.8 2.0 1.4 1 1 0 1 1 1 0 Sulfate transporter family SNARE_assoc PF09335.6 CBK23816.2 - 1.5 9.0 8.3 2.2 8.4 5.8 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein ABC2_membrane_4 PF12730.2 CBK23816.2 - 3 6.9 17.9 8.3 5.4 12.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Ribosom_S12_S23 PF00164.20 CBK23817.2 - 3.8e-43 145.8 3.4 4.4e-43 145.5 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Oxidored_q2 PF00420.19 CBK23818.2 - 3.1e-22 77.9 12.2 3.8e-22 77.7 8.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NADHdh PF00146.16 CBK23819.2 - 1.7e-119 398.5 23.3 2e-119 398.3 16.2 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Peptidase_M50 PF02163.17 CBK23819.2 - 0.044 12.7 0.0 0.085 11.8 0.0 1.8 1 1 0 1 1 1 0 Peptidase family M50 Molybdopterin PF00384.17 CBK23820.2 - 1.7e-23 83.0 0.2 5.2e-18 64.9 0.0 2.5 2 1 0 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 CBK23820.2 - 2.9e-17 61.6 0.3 2.9e-17 61.6 0.2 2.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.22 CBK23820.2 - 0.0019 17.9 0.8 0.011 15.4 0.0 2.1 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 CBK23820.2 - 0.11 12.9 2.1 0.28 11.6 1.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 CBK23820.2 - 1.6 9.0 5.5 1.3 9.4 1.8 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Oxidored_q1 PF00361.15 CBK23821.2 - 2e-49 168.2 45.4 2e-49 168.2 31.4 3.9 2 2 2 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF2648 PF10855.3 CBK23821.2 - 0.033 13.6 0.3 0.033 13.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2648) BNIP3 PF06553.7 CBK23821.2 - 8.5 5.6 5.5 22 4.3 0.6 2.4 2 0 0 2 2 2 0 BNIP3 Complex1_30kDa PF00329.14 CBK23822.2 - 1.5e-31 108.6 0.1 4.8e-31 107.0 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q1 PF00361.15 CBK23823.2 - 5.3e-83 278.3 25.4 5.3e-83 278.3 17.6 4.5 4 1 1 5 5 5 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 CBK23823.2 - 2.2e-24 84.7 10.2 2.2e-24 84.7 7.0 4.1 4 0 0 4 4 4 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.6 CBK23823.2 - 1.1e-13 50.9 40.2 8e-13 48.1 5.4 5.5 3 3 2 5 5 5 3 NADH dehydrogenase subunit 5 C-terminus Ribosomal_L14 PF00238.14 CBK23824.2 - 7.7e-19 67.6 5.9 1.2e-18 67.0 4.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e SF-assemblin PF06705.6 CBK23826.2 - 0.12 11.5 0.1 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin E1_DerP2_DerF2 PF02221.10 CBK23827.2 - 1.5e-12 47.9 0.1 1.7e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 ML domain DIM PF08194.7 CBK23827.2 - 0.015 15.2 0.7 0.51 10.3 0.1 2.5 2 0 0 2 2 2 0 DIM protein WD40 PF00400.27 CBK23828.2 - 3.7e-26 89.9 16.8 5.9e-08 32.3 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat tRNA-synt_1f PF01921.13 CBK23828.2 - 0.17 10.5 2.2 0.32 9.6 1.5 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) TFIIIC_delta PF12657.2 CBK23828.2 - 0.98 9.1 11.1 4.2 7.0 0.0 3.7 2 2 2 4 4 4 0 Transcription factor IIIC subunit delta N-term DUF1888 PF08985.6 CBK23830.2 - 0.016 14.9 0.0 3.5 7.3 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF1888) DUF563 PF04577.9 CBK23831.2 - 1.4e-20 74.0 1.4 2.1e-20 73.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_transf_49 PF13896.1 CBK23832.2 - 3.1e-12 46.2 1.3 1e-07 31.4 0.2 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK23832.2 - 0.0016 17.6 0.1 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FadA PF09403.5 CBK23833.2 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adhesion protein FadA Ribosomal_L7Ae PF01248.21 CBK23834.2 - 0.0027 17.1 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_49 PF13896.1 CBK23836.2 - 3.3e-09 36.2 3.4 1.5e-07 30.8 0.3 2.5 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK23836.2 - 0.00052 19.7 0.5 0.0013 18.4 0.2 1.7 1 1 0 1 1 1 1 F-box associated Glyco_hydro_35 PF01301.14 CBK23838.2 - 2.7e-19 69.6 0.0 3.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBK23838.2 - 0.044 12.9 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_35 PF01301.14 CBK23839.2 - 1.7e-35 122.9 2.3 2.6e-35 122.3 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CBK23839.2 - 5.6e-07 29.8 3.3 0.037 14.2 0.1 3.3 3 0 0 3 3 3 3 Beta-galactosidase jelly roll domain Glyco_hydro_2_N PF02837.13 CBK23839.2 - 0.012 15.2 5.7 0.071 12.6 0.1 2.7 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, sugar binding domain RabGAP-TBC PF00566.13 CBK23840.2 - 7.1e-14 51.7 1.8 7.1e-14 51.7 1.3 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1772 PF08592.6 CBK23840.2 - 0.053 13.2 0.1 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RabGAP-TBC PF00566.13 CBK23841.2 - 5.5e-26 91.3 0.0 1.3e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4090 PF13319.1 CBK23843.2 - 0.0095 15.8 1.0 0.012 15.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) IATP PF04568.7 CBK23843.2 - 0.02 14.9 5.3 0.025 14.5 3.4 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4460 PF14687.1 CBK23843.2 - 0.081 12.6 1.2 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF4432 PF14486.1 CBK23843.2 - 0.11 11.0 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) ACBP PF00887.14 CBK23844.2 - 1.7e-29 101.3 0.4 1.8e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TRIC PF05197.8 CBK23845.2 - 8e-08 31.9 0.4 1.3e-07 31.2 0.3 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 CBK23845.2 - 2e-05 24.0 2.7 0.012 15.2 0.2 2.2 2 0 0 2 2 2 2 UPF0126 domain Imm23 PF15593.1 CBK23846.2 - 0.087 13.0 1.4 0.14 12.3 1.0 1.4 1 0 0 1 1 1 0 Immunity protein 23 SNAP PF14938.1 CBK23847.2 - 3.2e-104 348.0 18.1 3.6e-104 347.8 12.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CBK23847.2 - 4.1e-12 45.5 14.7 3.8e-05 23.2 0.5 3.6 1 1 3 4 4 4 4 TPR repeat TPR_7 PF13176.1 CBK23847.2 - 3.8e-11 41.9 7.3 0.16 11.8 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK23847.2 - 9.5e-11 41.4 10.8 0.00013 21.8 0.5 3.8 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 CBK23847.2 - 3.3e-08 32.8 18.8 0.012 15.1 0.1 5.9 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBK23847.2 - 9.5e-08 31.4 17.5 0.39 10.7 0.0 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK23847.2 - 1.2e-07 31.9 5.5 0.0028 17.9 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK23847.2 - 1.5e-07 31.9 8.5 1.9e-05 25.2 0.8 3.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK23847.2 - 9e-07 28.9 12.6 0.5 10.9 0.4 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK23847.2 - 2e-06 27.9 2.5 11 6.9 0.0 5.5 4 1 3 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBK23847.2 - 2.2e-05 24.2 2.6 2.2 8.3 0.0 5.5 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK23847.2 - 0.00028 20.4 17.1 0.53 10.1 0.2 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat PPR PF01535.15 CBK23847.2 - 0.00051 19.8 7.1 3.9 7.6 0.1 4.5 3 1 1 4 4 4 2 PPR repeat Apc3 PF12895.2 CBK23847.2 - 0.0033 17.5 13.3 0.29 11.3 0.5 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Foie-gras_1 PF11817.3 CBK23847.2 - 0.006 16.0 2.1 2.2 7.6 0.0 2.5 1 1 1 2 2 2 2 Foie gras liver health family 1 MIT PF04212.13 CBK23847.2 - 0.016 15.0 10.7 3.8 7.4 0.1 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.1 CBK23847.2 - 0.028 14.3 7.6 2.7 8.0 0.1 4.0 3 1 1 4 4 4 0 PPR repeat family HHH_8 PF14716.1 CBK23847.2 - 0.061 13.5 5.7 1.9 8.7 0.0 3.8 4 1 0 4 4 3 0 Helix-hairpin-helix domain Sel1 PF08238.7 CBK23847.2 - 0.078 13.6 11.2 6.4 7.5 0.1 4.4 5 0 0 5 5 4 0 Sel1 repeat Clathrin PF00637.15 CBK23847.2 - 0.13 11.8 5.8 16 5.0 3.9 3.4 1 1 0 1 1 1 0 Region in Clathrin and VPS RPN7 PF10602.4 CBK23847.2 - 0.22 10.8 9.6 1.2 8.5 0.0 3.9 1 1 3 4 4 4 0 26S proteasome subunit RPN7 PPR_1 PF12854.2 CBK23847.2 - 0.28 10.7 2.6 38 3.8 0.1 3.5 3 0 0 3 3 3 0 PPR repeat NSF PF02071.15 CBK23847.2 - 9.5 7.3 29.1 0.88 10.4 0.2 7.1 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat vATP-synt_E PF01991.13 CBK23848.2 - 1.9e-48 164.4 4.1 2.2e-48 164.1 2.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OmpH PF03938.9 CBK23848.2 - 8.8 6.2 22.2 14 5.5 15.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 CBK23849.2 - 1.3e-28 99.8 0.0 1.5e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23849.2 - 2e-16 59.8 0.0 2.6e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23849.2 - 0.00089 18.3 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBK23849.2 - 0.096 11.4 0.1 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CBK23849.2 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CBK23850.2 - 7.9e-73 244.8 0.0 9.7e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23850.2 - 2.2e-28 99.0 0.0 3.1e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23850.2 - 0.0033 16.4 0.0 0.025 13.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBK23850.2 - 0.0034 17.1 0.1 0.0076 16.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family AP2 PF00847.15 CBK23850.2 - 0.2 11.8 0.8 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AP2 domain Rad51 PF08423.6 CBK23852.2 - 6.2e-132 438.1 0.0 1e-131 437.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBK23852.2 - 3.7e-15 55.8 0.0 5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBK23852.2 - 2.8e-11 43.0 0.1 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBK23852.2 - 5.7e-07 29.6 0.5 1.4e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBK23852.2 - 6.5e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CBK23852.2 - 0.00012 21.0 0.0 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CBK23852.2 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein AAA PF00004.24 CBK23852.2 - 0.085 13.0 0.0 0.49 10.5 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK23852.2 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain POR_N PF01855.14 CBK23853.2 - 1.4e-57 194.9 0.1 2.7e-57 193.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.13 CBK23853.2 - 2.9e-25 89.1 1.7 3.3e-25 88.9 0.2 1.9 2 0 0 2 2 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.4 CBK23853.2 - 6.8e-13 47.9 0.0 1.9e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function Fer4_7 PF12838.2 CBK23853.2 - 3.8e-09 36.7 6.8 3.8e-09 36.7 4.7 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK23853.2 - 1e-08 35.3 5.9 0.00019 21.6 1.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain TPP_enzyme_C PF02775.16 CBK23853.2 - 1.8e-08 34.1 0.4 5.9e-08 32.4 0.3 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.1 CBK23853.2 - 2.3e-07 30.4 10.4 1.1e-05 25.0 7.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 CBK23853.2 - 2.5e-07 29.9 19.2 8.9e-05 21.9 1.0 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.1 CBK23853.2 - 1.7e-06 28.6 8.6 2.2e-05 25.1 5.9 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 CBK23853.2 - 5.4e-06 26.3 10.8 6.6e-06 26.0 6.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK23853.2 - 2.7e-05 23.8 16.6 0.0026 17.5 1.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.1 CBK23853.2 - 2.9e-05 23.8 14.2 0.00049 19.8 9.9 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK23853.2 - 0.00035 20.9 9.4 0.036 14.4 0.6 3.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK23853.2 - 0.00093 18.9 19.8 0.01 15.6 1.6 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CBK23853.2 - 0.0013 19.0 11.1 0.0037 17.5 6.7 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK23853.2 - 0.024 14.5 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fer4_4 PF12800.2 CBK23853.2 - 0.026 14.8 20.1 0.027 14.7 2.8 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_13 PF13370.1 CBK23853.2 - 0.06 13.7 10.4 0.33 11.3 0.7 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 CBK23853.2 - 0.26 11.8 8.7 2.8 8.5 0.2 3.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain Ribosomal_L22 PF00237.14 CBK23855.2 - 1.1e-28 99.2 0.1 1.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HORMA PF02301.13 CBK23857.2 - 3.6e-47 160.5 0.4 7.1e-47 159.5 0.0 1.6 2 0 0 2 2 2 1 HORMA domain Ribosomal_L16 PF00252.13 CBK23858.2 - 8.2e-31 106.5 0.2 1e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.3 CBK23858.2 - 0.14 11.8 0.3 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme zf-CCHC PF00098.18 CBK23859.2 - 8.8e-58 189.6 57.2 3.4e-10 39.3 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CBK23859.2 - 1e-17 63.3 44.5 0.00067 19.1 1.7 7.1 4 1 3 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CBK23859.2 - 1e-11 44.3 38.0 0.028 14.1 0.1 7.1 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CBK23859.2 - 2e-09 36.9 46.7 0.047 13.3 0.8 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 CBK23859.2 - 0.0002 20.9 51.9 0.0026 17.4 1.1 7.1 5 2 2 7 7 7 4 Zinc knuckle zf-CCHC_5 PF14787.1 CBK23859.2 - 0.024 14.1 1.4 0.024 14.1 1.0 6.7 6 1 1 7 7 7 0 GAG-polyprotein viral zinc-finger ZZ PF00569.12 CBK23859.2 - 2.6 7.6 31.9 2.3 7.8 0.2 6.4 4 1 3 7 7 7 0 Zinc finger, ZZ type NAC PF01849.13 CBK23861.2 - 7.3e-12 44.6 1.2 1.6e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBK23861.2 - 0.0001 22.0 0.3 0.0002 21.1 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBK23861.2 - 0.0043 16.5 0.1 0.021 14.3 0.1 2.2 2 1 0 2 2 2 1 UBA-like domain Peptidase_S49_N PF08496.5 CBK23861.2 - 0.025 14.3 0.3 0.025 14.3 0.2 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Zip PF02535.17 CBK23861.2 - 0.05 12.5 2.7 0.065 12.2 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter N-SET PF11764.3 CBK23861.2 - 0.2 11.5 3.0 0.15 11.9 0.2 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N CT47 PF15623.1 CBK23861.2 - 3 7.4 19.9 0.05 13.3 5.9 2.1 2 0 0 2 2 2 0 Cancer/testis gene family 47 Brix PF04427.13 CBK23862.2 - 2.3e-38 131.8 0.1 3e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF382 PF04037.8 CBK23863.2 - 1e-51 174.1 0.0 2e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 CBK23863.2 - 3.1e-20 71.3 8.2 5.8e-20 70.4 5.7 1.5 1 0 0 1 1 1 1 PSP Adaptin_N PF01602.15 CBK23864.2 - 1.6e-112 376.5 3.2 2.1e-112 376.1 2.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CBK23864.2 - 2.2e-19 69.8 0.1 4.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.2 CBK23864.2 - 0.00044 20.1 3.3 0.0054 16.5 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Med3 PF11593.3 CBK23864.2 - 0.0059 15.8 1.2 0.0099 15.1 0.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal V-SNARE_C PF12352.3 CBK23865.2 - 1.8e-07 31.1 4.3 2.8e-07 30.4 0.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Cyclin PF08613.6 CBK23866.2 - 3.6e-34 118.3 0.2 5e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBK23866.2 - 7.6e-12 44.8 0.0 1.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain ELO PF01151.13 CBK23867.2 - 2.2e-51 174.5 28.6 2.7e-51 174.3 19.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3311 PF11755.3 CBK23867.2 - 0.022 14.2 1.0 0.66 9.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) YwiC PF14256.1 CBK23867.2 - 0.15 12.1 0.1 0.15 12.1 0.1 2.5 2 1 0 2 2 2 0 YwiC-like protein C2 PF00168.25 CBK23868.2 - 1.6e-10 40.7 0.1 2.3e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 C2 domain Copine PF07002.11 CBK23869.2 - 7.4e-43 145.7 0.0 1.4e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 CBK23869.2 - 1.7e-06 27.9 0.0 3.3e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus EspA PF03433.8 CBK23869.2 - 0.14 11.6 0.1 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 EspA-like secreted protein ATP-synt_F PF01990.12 CBK23870.2 - 3e-30 104.4 1.6 3.5e-30 104.2 1.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Lipase_3 PF01764.20 CBK23871.2 - 5.8e-06 25.9 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CBK23871.2 - 0.0045 16.8 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CBK23871.2 - 0.015 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBK23871.2 - 0.027 14.2 0.0 0.058 13.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Arf PF00025.16 CBK23872.2 - 2e-15 56.4 0.0 4.5e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBK23872.2 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK23872.2 - 0.037 13.4 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PAP_assoc PF03828.14 CBK23872.2 - 0.26 11.2 1.6 14 5.6 0.6 2.4 2 0 0 2 2 2 0 Cid1 family poly A polymerase PP-binding PF00550.20 CBK23873.2 - 3.2e-10 40.1 0.4 3.3e-10 40.0 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CBK23873.2 - 0.0017 18.3 0.6 0.002 18.0 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier TAF PF02969.12 CBK23873.2 - 0.032 14.1 0.1 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Guanylate_cyc PF00211.15 CBK23873.2 - 0.04 13.2 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Glu-tRNAGln PF02686.10 CBK23873.2 - 0.078 12.7 0.1 0.094 12.5 0.1 1.3 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DEAD PF00270.24 CBK23874.2 - 2.1e-40 137.9 0.0 6.8e-40 136.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK23874.2 - 1.1e-29 102.1 0.1 6.2e-29 99.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBK23874.2 - 0.026 12.9 0.0 0.45 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CBK23874.2 - 0.028 14.5 0.1 0.071 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.18 CBK23875.2 - 5.7e-73 245.4 3.1 7.4e-73 245.0 2.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK23875.2 - 2.8e-11 43.4 2.9 4.9e-11 42.7 2.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBK23875.2 - 0.0077 14.8 1.8 1.1 7.7 0.1 2.4 2 1 0 2 2 2 2 Peptidase C1-like family ER PF01133.12 CBK23876.2 - 2e-14 53.1 0.2 2.5e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary HSP70 PF00012.15 CBK23877.2 - 3.7e-112 375.2 0.1 2.9e-90 302.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBK23877.2 - 6.6e-11 41.3 0.4 3.7e-10 38.9 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK23877.2 - 0.46 10.3 4.8 10 6.0 0.9 3.9 2 2 0 2 2 2 0 Cell division protein FtsA SOBP PF15279.1 CBK23877.2 - 2.5 8.3 23.2 4.1 7.7 16.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Lyase_1 PF00206.15 CBK23878.2 - 3.4e-93 312.2 0.0 4.8e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 Lyase SWIB PF02201.13 CBK23878.2 - 7.2e-25 86.4 1.8 1.3e-15 56.8 0.0 2.8 3 0 0 3 3 3 2 SWIB/MDM2 domain FumaraseC_C PF10415.4 CBK23878.2 - 2.8e-17 62.4 0.0 7.6e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus DEK_C PF08766.6 CBK23878.2 - 1.2e-12 47.3 1.1 3.1e-12 46.0 0.8 1.7 1 0 0 1 1 1 1 DEK C terminal domain Tweety PF04906.8 CBK23879.2 - 0.088 11.2 0.1 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Tweety SdiA-regulated PF06977.6 CBK23879.2 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 SdiA-regulated CPSase_L_D2 PF02786.12 CBK23880.2 - 2.7e-72 242.4 0.0 4.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK23880.2 - 6.2e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK23880.2 - 7.8e-35 119.1 0.0 1.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK23880.2 - 2.8e-18 65.3 0.2 5.9e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK23880.2 - 1.8e-09 36.7 0.0 4.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK23880.2 - 3.8e-08 32.8 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK23880.2 - 4.5e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK23880.2 - 7.7e-08 31.9 0.1 3.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK23880.2 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK23880.2 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK23880.2 - 0.0024 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK23880.2 - 0.0037 16.9 0.4 0.012 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK23880.2 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK23880.2 - 0.015 15.6 0.0 0.46 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK23880.2 - 0.041 13.9 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK23880.2 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK23880.2 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK23880.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DNA_pol_E_B PF04042.11 CBK23881.2 - 4.2e-15 55.5 0.0 5.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COPIIcoated_ERV PF07970.7 CBK23882.2 - 1.1e-16 61.2 0.9 1.1e-16 61.1 0.6 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Shisa PF13908.1 CBK23883.2 - 0.00012 22.3 1.5 0.00021 21.5 1.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.6 CBK23883.2 - 0.0076 15.8 0.7 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein TMEM154 PF15102.1 CBK23883.2 - 0.017 14.8 1.1 0.043 13.5 0.8 1.7 1 1 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.1 CBK23883.2 - 0.068 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein GRP PF07172.6 CBK23883.2 - 1 9.8 13.0 2.9 8.4 7.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family Sulfatase PF00884.18 CBK23884.2 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Sulfatase TPT PF03151.11 CBK23885.2 - 3.7e-07 29.8 4.4 4.3e-07 29.6 3.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.15 CBK23885.2 - 0.029 14.4 0.5 0.034 14.1 0.3 1.2 1 0 0 1 1 1 0 EamA-like transporter family UAA PF08449.6 CBK23886.2 - 0.005 15.7 0.6 0.0066 15.4 0.4 1.1 1 0 0 1 1 1 1 UAA transporter family AsmA_1 PF13109.1 CBK23886.2 - 0.087 12.0 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region Tenui_NS3 PF05310.7 CBK23886.2 - 0.15 11.9 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus movement protein EamA PF00892.15 CBK23886.2 - 3.6 7.6 7.9 0.35 10.9 0.3 2.3 3 0 0 3 3 3 0 EamA-like transporter family Pkinase PF00069.20 CBK23887.2 - 5.5e-10 38.8 0.0 6.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23887.2 - 2.1e-05 23.7 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBK23888.2 - 6.3e-33 114.0 0.0 2.5e-32 112.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23888.2 - 2.8e-19 69.2 0.0 8.4e-19 67.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23888.2 - 1e-07 31.2 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK23888.2 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.27 CBK23889.2 - 2.9e-31 106.2 11.3 3.8e-09 36.0 0.6 4.5 4 1 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK23889.2 - 0.13 10.3 0.2 1.3 7.1 0.1 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase PF00069.20 CBK23890.2 - 3.4e-16 59.1 0.0 5e-15 55.3 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23890.2 - 1.5e-13 50.4 0.0 1.4e-12 47.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Spore_III_AF PF09581.5 CBK23890.2 - 0.14 12.0 0.5 0.24 11.2 0.3 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Histone PF00125.19 CBK23891.2 - 3.5e-33 113.5 0.8 5.5e-33 112.9 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK23891.2 - 2.9e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBK23891.2 - 0.0043 17.0 0.1 0.0087 16.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBK23891.2 - 0.14 11.4 1.1 0.35 10.0 0.1 1.7 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T PIG-Y PF15159.1 CBK23892.2 - 0.023 14.8 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y UPF0242 PF06785.6 CBK23892.2 - 0.085 11.5 0.6 0.1 11.2 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) EPL1 PF10513.4 CBK23893.2 - 4.9e-14 52.8 0.3 9.6e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like KH_1 PF00013.24 CBK23894.2 - 1.7e-05 24.3 1.3 3.5e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 KH domain tRNA-synt_2b PF00587.20 CBK23895.2 - 1.4e-37 128.9 0.1 2.1e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBK23895.2 - 2.1e-24 85.5 4.6 4.1e-24 84.6 3.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.6 CBK23895.2 - 0.26 10.0 4.7 0.42 9.3 3.3 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein IncA PF04156.9 CBK23895.2 - 0.72 9.4 2.5 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein zf-RING_2 PF13639.1 CBK23896.2 - 6.7e-15 54.6 6.8 1.1e-14 53.9 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBK23896.2 - 3.2e-09 36.6 7.2 5.5e-09 35.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23896.2 - 1.3e-08 34.3 5.7 2e-08 33.8 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBK23896.2 - 3.8e-08 33.3 7.6 6.3e-08 32.6 5.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBK23896.2 - 6.9e-08 32.0 7.3 1e-07 31.4 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23896.2 - 6.9e-08 32.0 5.6 1.1e-07 31.3 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBK23896.2 - 4.9e-06 26.2 5.6 9.1e-06 25.4 3.9 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBK23896.2 - 0.0029 17.2 1.9 0.0029 17.2 1.3 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBK23896.2 - 0.0037 16.8 3.7 0.0058 16.1 2.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CBK23896.2 - 0.025 14.5 7.2 0.32 10.9 5.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1989 PF09347.5 CBK23896.2 - 0.038 13.4 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) Baculo_RING PF05883.6 CBK23896.2 - 0.043 13.6 2.5 0.07 12.9 1.7 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 CBK23896.2 - 0.06 13.0 10.0 0.26 11.0 5.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 CBK23896.2 - 0.28 11.2 6.7 0.55 10.3 4.7 1.5 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 CBK23896.2 - 2.3 8.0 11.0 1.7 8.4 5.3 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_1 PF00583.19 CBK23897.2 - 1.7e-07 31.1 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBK23897.2 - 1.1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK23897.2 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBK23897.2 - 0.00046 20.2 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBK23897.2 - 0.012 15.5 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK23897.2 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TRAM1 PF08390.6 CBK23898.2 - 0.074 12.5 0.5 0.074 12.5 0.3 1.5 2 0 0 2 2 2 0 TRAM1-like protein FixQ PF05545.6 CBK23898.2 - 6.7 6.4 6.1 15 5.3 4.2 1.7 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ eIF2A PF08662.6 CBK23900.2 - 2.3e-44 151.4 0.0 3e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CBK23900.2 - 1.2e-06 28.2 0.5 0.0021 17.8 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Metallophos PF00149.23 CBK23901.2 - 9e-41 139.4 0.2 1.2e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-DHHC PF01529.15 CBK23902.2 - 7.5e-23 80.8 9.6 8.3e-23 80.6 6.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase zf-RanBP PF00641.13 CBK23902.2 - 0.022 13.8 1.3 0.057 12.5 0.9 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Auto_anti-p27 PF06677.7 CBK23902.2 - 0.75 9.6 6.5 2.8 7.7 0.1 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MFS_1 PF07690.11 CBK23903.2 - 2.9e-06 26.2 0.0 3.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HEAT PF02985.17 CBK23905.2 - 1.4e-07 30.9 2.7 1.3 9.3 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CBK23905.2 - 5.7e-07 29.7 0.4 0.76 10.0 0.0 5.3 2 2 4 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 CBK23905.2 - 5.7e-05 23.4 0.6 1.6 9.3 0.0 5.9 5 1 1 6 6 6 1 HEAT-like repeat DUF2454 PF10521.4 CBK23905.2 - 0.00085 18.4 0.3 0.9 8.4 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2454) FliH PF02108.11 CBK23905.2 - 0.034 14.0 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH DUF3385 PF11865.3 CBK23905.2 - 0.63 9.9 7.4 0.18 11.7 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) hSac2 PF12456.3 CBK23906.2 - 0.056 12.8 0.4 1.6 8.1 0.0 3.1 2 1 2 4 4 4 0 Inositol phosphatase LRR_8 PF13855.1 CBK23907.2 - 0.003 17.2 1.1 0.48 10.2 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat hSac2 PF12456.3 CBK23907.2 - 0.011 15.1 1.1 1.8 7.9 0.0 3.3 1 1 2 3 3 3 0 Inositol phosphatase MORN_2 PF07661.8 CBK23907.2 - 7.1 7.0 12.4 29 5.1 0.1 4.1 4 0 0 4 4 4 0 MORN repeat variant DNA_pol_phi PF04931.8 CBK23908.2 - 3.5e-12 44.9 31.2 4.5e-12 44.5 21.6 1.2 1 0 0 1 1 1 1 DNA polymerase phi CENP-T PF15511.1 CBK23908.2 - 0.0064 15.7 13.6 0.011 15.0 9.4 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T DUF1510 PF07423.6 CBK23908.2 - 0.0064 15.8 20.5 0.0064 15.8 14.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Zip PF02535.17 CBK23908.2 - 0.059 12.3 1.1 0.075 12.0 0.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CBK23908.2 - 1.2 8.8 12.7 0.019 14.7 3.2 2.0 2 1 0 2 2 2 0 DDHD domain GAGA_bind PF06217.7 CBK23908.2 - 1.7 8.5 4.9 3.3 7.5 3.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Mem_trans PF03547.13 CBK23908.2 - 6.4 4.9 6.8 4.2 5.5 3.5 1.5 2 0 0 2 2 2 0 Membrane transport protein CPSF100_C PF13299.1 CBK23908.2 - 6.6 6.8 13.3 0.44 10.7 5.5 1.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PH_7 PF15408.1 CBK23909.2 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Leuk-A4-hydro_C PF09127.6 CBK23910.2 - 0.04 13.4 0.1 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Ribosomal_L28e PF01778.12 CBK23911.2 - 4.6e-32 110.8 3.0 4.6e-32 110.8 2.1 1.9 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CBK23911.2 - 2.8e-19 69.0 14.3 2.8e-19 69.0 9.9 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.10 CBK23911.2 - 0.33 10.1 6.6 0.45 9.6 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BRICHOS PF04089.9 CBK23911.2 - 1.8 8.5 6.7 2.5 8.0 0.1 3.0 2 1 1 3 3 3 0 BRICHOS domain DUF4168 PF13767.1 CBK23911.2 - 2.3 8.9 7.0 4.1 8.0 2.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Sds3 PF08598.6 CBK23912.2 - 0.0024 17.4 3.5 0.003 17.1 2.5 1.4 1 1 0 1 1 1 1 Sds3-like Taeniidae_ag PF05596.6 CBK23913.2 - 0.042 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Taeniidae antigen HSP20 PF00011.16 CBK23914.2 - 1.6e-19 69.6 0.0 2.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4062 PF13271.1 CBK23914.2 - 0.14 12.2 0.9 17 5.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4062) NAD_binding_2 PF03446.10 CBK23915.2 - 3.5e-05 23.6 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Vert_HS_TF PF06546.6 CBK23915.2 - 0.095 12.0 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Bromodomain PF00439.20 CBK23916.2 - 3.5e-09 36.4 0.0 8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ApoLp-III PF07464.6 CBK23916.2 - 0.02 14.9 1.8 0.039 13.9 1.3 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FGase PF05013.7 CBK23916.2 - 0.055 13.3 0.4 0.076 12.8 0.3 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase GAGA_bind PF06217.7 CBK23916.2 - 0.068 13.1 1.6 0.089 12.7 1.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tup_N PF08581.5 CBK23916.2 - 0.28 11.3 3.5 0.85 9.8 0.1 3.1 3 1 0 3 3 3 0 Tup N-terminal UPF0126 PF03458.8 CBK23917.2 - 2.3e-05 23.9 1.1 2.3e-05 23.9 0.7 2.6 3 0 0 3 3 3 1 UPF0126 domain TRIC PF05197.8 CBK23917.2 - 5.5 6.3 8.6 3.3 7.0 0.6 2.7 1 1 2 3 3 3 0 TRIC channel Rep_fac_C PF08542.6 CBK23918.2 - 4.3e-14 52.2 0.5 2.3e-13 49.8 0.0 2.5 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBK23918.2 - 2.8e-13 49.8 0.3 5.4e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBK23918.2 - 5.9e-08 32.9 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBK23918.2 - 0.00087 18.0 0.1 0.0014 17.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 CBK23918.2 - 0.0019 18.2 0.1 0.014 15.4 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 CBK23918.2 - 0.0045 17.1 0.2 0.031 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK23918.2 - 0.0076 16.2 0.1 0.099 12.6 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CBK23918.2 - 0.0083 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBK23918.2 - 0.013 15.3 0.0 0.068 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK23918.2 - 0.015 14.7 0.0 0.073 12.5 0.0 1.9 1 1 2 3 3 3 0 AAA-like domain Bac_DnaA PF00308.13 CBK23918.2 - 0.016 14.8 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein DNA_pol3_delta PF06144.8 CBK23918.2 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 CBK23918.2 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.17 CBK23919.2 - 4.4e-72 243.0 0.3 6e-72 242.5 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain GTP_EFTU PF00009.22 CBK23920.2 - 3e-62 209.4 0.0 5.1e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBK23920.2 - 1.2e-33 115.2 0.0 2.8e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBK23920.2 - 1.1e-19 70.0 0.0 2.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBK23920.2 - 5.2e-15 55.0 0.0 1.5e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBK23920.2 - 7.4e-13 48.4 0.1 2.3e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK23920.2 - 9.8e-05 22.2 0.0 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2703 PF10865.3 CBK23920.2 - 0.12 12.3 0.1 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) zf-CCCH PF00642.19 CBK23921.2 - 2.1e-05 24.1 23.9 2.6e-05 23.7 3.5 2.8 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CBK23921.2 - 5 6.6 8.1 14 5.2 0.1 3.3 3 0 0 3 3 3 0 Putative zinc-finger domain TBPIP PF07106.8 CBK23922.2 - 4.6e-43 146.7 7.2 5.6e-43 146.4 5.0 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 CBK23922.2 - 1e-05 25.2 6.9 1.3e-05 24.9 4.8 1.2 1 0 0 1 1 1 1 Mnd1 family Reo_sigmaC PF04582.7 CBK23922.2 - 0.00041 19.6 0.2 0.00055 19.2 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DivIC PF04977.10 CBK23922.2 - 0.00062 19.2 7.4 0.084 12.3 2.8 3.0 1 1 1 2 2 2 2 Septum formation initiator Penicillinase_R PF03965.11 CBK23922.2 - 0.0024 17.9 2.2 0.083 12.9 0.2 3.0 1 1 3 4 4 4 1 Penicillinase repressor WEMBL PF05701.6 CBK23922.2 - 0.0031 16.0 10.5 0.0039 15.7 7.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light V_ATPase_I PF01496.14 CBK23922.2 - 0.016 13.0 5.9 0.019 12.8 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.4 CBK23922.2 - 0.019 15.0 6.4 0.02 15.0 3.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 CBK23922.2 - 0.023 15.0 9.9 0.59 10.5 2.3 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF972) FlxA PF14282.1 CBK23922.2 - 0.024 14.5 3.8 0.042 13.7 1.9 1.9 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 CBK23922.2 - 0.025 14.1 12.8 0.032 13.8 8.2 1.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 CBK23922.2 - 0.025 14.4 8.6 0.87 9.4 3.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.6 CBK23922.2 - 0.032 14.0 13.6 0.13 12.1 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 CBK23922.2 - 0.042 13.6 7.5 0.078 12.8 5.2 1.5 1 0 0 1 1 1 0 Tropomyosin like AAA_27 PF13514.1 CBK23922.2 - 0.055 11.1 9.4 0.25 9.0 6.4 1.8 1 1 1 2 2 2 0 AAA domain SCO1-SenC PF02630.9 CBK23922.2 - 0.055 13.0 0.6 0.27 10.8 0.3 1.9 1 1 1 2 2 2 0 SCO1/SenC CENP-F_leu_zip PF10473.4 CBK23922.2 - 0.056 13.3 9.9 0.13 12.1 6.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PilJ PF13675.1 CBK23922.2 - 0.056 13.7 3.6 0.08 13.2 0.4 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term WXG100 PF06013.7 CBK23922.2 - 0.058 13.4 3.3 0.68 9.9 1.2 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.7 CBK23922.2 - 0.058 13.2 0.4 0.18 11.5 0.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 CBK23922.2 - 0.069 12.9 8.8 0.53 10.0 1.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Pro_dh PF01619.13 CBK23922.2 - 0.07 12.1 2.4 0.089 11.7 1.6 1.3 1 0 0 1 1 1 0 Proline dehydrogenase bZIP_1 PF00170.16 CBK23922.2 - 0.075 12.9 9.5 0.13 12.2 2.6 2.9 2 1 1 3 3 3 0 bZIP transcription factor AAA_13 PF13166.1 CBK23922.2 - 0.09 11.2 6.2 0.12 10.8 4.3 1.3 1 0 0 1 1 1 0 AAA domain NUC194 PF08163.7 CBK23922.2 - 0.092 11.5 4.6 0.11 11.2 3.2 1.1 1 0 0 1 1 1 0 NUC194 domain Chorismate_synt PF01264.16 CBK23922.2 - 0.098 11.1 0.4 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 Chorismate synthase Cep57_CLD_2 PF14197.1 CBK23922.2 - 0.11 12.4 6.6 1.2 9.1 4.5 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 FUSC PF04632.7 CBK23922.2 - 0.14 10.6 1.3 0.17 10.2 0.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seadorna_VP6 PF07407.6 CBK23922.2 - 0.14 10.8 1.2 0.19 10.4 0.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein TMF_DNA_bd PF12329.3 CBK23922.2 - 0.17 11.6 13.7 0.47 10.3 7.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3166 PF11365.3 CBK23922.2 - 0.2 12.1 7.4 0.73 10.3 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) APG6 PF04111.7 CBK23922.2 - 0.24 10.4 12.0 0.1 11.6 6.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 CBK23922.2 - 0.26 11.4 6.0 0.75 9.9 0.9 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 CBK23922.2 - 0.31 11.4 6.5 1.7 9.0 1.7 2.9 1 1 2 3 3 3 0 SlyX Snapin_Pallidin PF14712.1 CBK23922.2 - 0.33 11.2 7.2 0.33 11.2 3.1 2.2 2 1 1 3 3 2 0 Snapin/Pallidin TMF_TATA_bd PF12325.3 CBK23922.2 - 0.36 10.5 13.4 0.77 9.4 5.6 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.13 CBK23922.2 - 0.42 10.0 4.9 0.22 10.9 1.4 1.8 1 1 0 2 2 2 0 FtsK/SpoIIIE family Prefoldin_2 PF01920.15 CBK23922.2 - 0.46 10.2 10.9 4 7.2 4.0 2.9 1 1 3 4 4 4 0 Prefoldin subunit Spc24 PF08286.6 CBK23922.2 - 0.47 10.1 8.3 1.2 8.8 4.3 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.8 CBK23922.2 - 0.48 10.1 7.4 0.17 11.6 1.8 2.4 2 2 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.4 CBK23922.2 - 0.58 9.0 6.0 0.97 8.3 4.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CBK23922.2 - 0.72 8.1 9.8 0.41 9.0 3.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 CBK23922.2 - 0.72 9.6 13.5 0.33 10.7 5.0 2.7 1 1 2 3 3 3 0 Axonemal dynein light chain FliJ PF02050.11 CBK23922.2 - 0.78 9.8 9.5 0.45 10.5 2.9 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein PspB PF06667.7 CBK23922.2 - 0.82 9.6 3.3 2.4 8.1 0.4 2.5 1 1 1 2 2 2 0 Phage shock protein B HALZ PF02183.13 CBK23922.2 - 1 9.1 7.7 0.86 9.3 1.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper CCDC155 PF14662.1 CBK23922.2 - 1.2 8.6 12.6 1.7 8.1 7.3 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Metal_resist PF13801.1 CBK23922.2 - 1.3 9.0 4.7 0.64 10.0 1.5 1.8 1 1 1 2 2 2 0 Heavy-metal resistance TPR_MLP1_2 PF07926.7 CBK23922.2 - 1.4 8.7 9.7 6 6.6 6.7 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 CBK23922.2 - 1.4 9.3 7.0 1.5 9.3 0.9 2.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.1 CBK23922.2 - 1.4 9.1 10.4 1.9 8.7 7.2 1.2 1 0 0 1 1 1 0 AAA domain GrpE PF01025.14 CBK23922.2 - 1.5 8.3 11.5 0.47 9.9 0.5 2.6 1 1 2 3 3 3 0 GrpE Seryl_tRNA_N PF02403.17 CBK23922.2 - 1.8 8.6 10.3 1.7 8.6 5.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.10 CBK23922.2 - 2.1 8.5 11.0 5.3 7.2 1.4 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SYF2 PF08231.7 CBK23922.2 - 2.2 8.4 7.9 3.3 7.8 0.4 2.6 1 1 1 2 2 2 0 SYF2 splicing factor BRE1 PF08647.6 CBK23922.2 - 2.5 8.1 10.2 0.94 9.4 0.9 2.9 1 1 2 3 3 2 0 BRE1 E3 ubiquitin ligase DUF1843 PF08898.5 CBK23922.2 - 2.7 8.1 12.8 4.8 7.3 0.8 4.0 2 1 2 4 4 3 0 Domain of unknown function (DUF1843) FlaC_arch PF05377.6 CBK23922.2 - 3.5 7.5 11.2 0.54 10.1 1.6 3.4 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Striatin PF08232.7 CBK23922.2 - 5.6 7.2 10.2 10 6.4 6.5 1.9 1 1 0 1 1 1 0 Striatin family TBCA PF02970.11 CBK23922.2 - 6.2 6.9 10.8 5.8 7.0 4.3 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A bZIP_2 PF07716.10 CBK23922.2 - 6.2 6.7 11.7 5.2 6.9 1.4 2.8 3 0 0 3 3 2 0 Basic region leucine zipper Pkinase PF00069.20 CBK23923.2 - 2.2e-34 118.7 0.0 2.6e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23923.2 - 7.7e-12 44.8 0.0 9.6e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK23923.2 - 0.0018 18.0 0.0 0.14 11.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family UBA_4 PF14555.1 CBK23924.2 - 2.1e-07 30.3 0.0 4.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-UBP PF02148.14 CBK23924.2 - 0.0005 20.1 2.2 0.0005 20.1 1.5 2.3 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2180 PF09947.4 CBK23924.2 - 0.0081 15.8 1.1 0.026 14.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2180) UCH PF00443.24 CBK23925.2 - 2.3e-28 99.0 0.3 3.4e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBK23925.2 - 5.4e-17 61.6 11.0 5.4e-17 61.6 7.6 2.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBK23925.2 - 1.1e-11 44.7 2.6 2.3e-10 40.4 1.8 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CBK23925.2 - 0.00014 21.2 0.9 0.023 13.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UPF1_Zn_bind PF09416.5 CBK23925.2 - 0.11 12.0 7.3 0.059 12.9 2.9 2.1 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) DUF3795 PF12675.2 CBK23925.2 - 5.1 7.3 14.5 5.5 7.2 0.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) UCH PF00443.24 CBK23926.2 - 1.3e-10 40.9 0.1 1.3e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK23926.2 - 9e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8e PF01201.17 CBK23927.2 - 3.3e-39 134.0 2.9 1.4e-38 132.0 2.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e SAP PF02037.22 CBK23930.2 - 4.7e-07 29.1 0.0 7.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SAP domain DUF4407 PF14362.1 CBK23930.2 - 3.1 6.6 7.8 5.9 5.7 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) fn3 PF00041.16 CBK23931.2 - 2.9e-10 40.1 0.1 9.9e-05 22.4 0.0 4.8 5 0 0 5 5 5 3 Fibronectin type III domain Big_5 PF13205.1 CBK23931.2 - 6.5e-07 29.9 2.9 0.038 14.5 0.0 5.1 4 1 1 5 5 5 2 Bacterial Ig-like domain Pentapeptide_2 PF01469.13 CBK23931.2 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Mnd1 PF03962.10 CBK23932.2 - 9.4e-49 165.6 9.2 1.1e-48 165.4 6.4 1.0 1 0 0 1 1 1 1 Mnd1 family YscO PF07321.7 CBK23932.2 - 8.8e-05 22.3 6.3 0.00015 21.6 4.4 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO TBPIP PF07106.8 CBK23932.2 - 9.6e-05 21.9 5.6 0.00013 21.5 3.9 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CBK23932.2 - 0.0017 17.4 4.2 0.002 17.1 2.9 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CBK23932.2 - 0.0061 16.0 9.3 0.37 10.2 0.8 2.8 2 1 1 3 3 3 2 Septum formation initiator DUF2252 PF10009.4 CBK23932.2 - 0.011 14.6 1.9 0.015 14.2 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Spc7 PF08317.6 CBK23932.2 - 0.03 13.0 6.0 0.041 12.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1932 PF09130.6 CBK23932.2 - 0.032 13.9 0.5 0.86 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1932) Allexi_40kDa PF05549.6 CBK23932.2 - 0.057 12.7 0.9 0.07 12.4 0.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein GldM_N PF12081.3 CBK23932.2 - 0.061 12.8 2.0 0.16 11.4 1.3 1.6 1 1 0 1 1 1 0 GldM N-terminal domain HALZ PF02183.13 CBK23932.2 - 0.061 13.0 9.1 0.3 10.8 0.5 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper ParBc PF02195.13 CBK23932.2 - 0.066 13.3 0.9 0.49 10.5 0.6 2.1 1 1 0 1 1 1 0 ParB-like nuclease domain Methyltransf_28 PF02636.12 CBK23932.2 - 0.083 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4226 PF10774.4 CBK23932.2 - 0.1 12.6 2.4 6.3 6.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Borrelia_REV PF03978.8 CBK23932.2 - 0.12 12.1 2.0 0.18 11.4 0.9 1.9 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein Seryl_tRNA_N PF02403.17 CBK23932.2 - 0.17 11.8 8.1 0.18 11.8 3.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pil1 PF13805.1 CBK23932.2 - 0.27 10.3 5.6 0.46 9.5 3.8 1.4 1 1 0 1 1 1 0 Eisosome component PIL1 APG6 PF04111.7 CBK23932.2 - 0.35 9.8 5.7 0.43 9.5 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBK23932.2 - 0.4 8.4 4.4 0.48 8.2 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CBK23932.2 - 0.57 8.5 11.4 0.086 11.2 4.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF342) DUF904 PF06005.7 CBK23932.2 - 1 9.6 11.2 4.5 7.6 6.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Snapin_Pallidin PF14712.1 CBK23932.2 - 1.1 9.6 5.8 11 6.3 1.1 2.6 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.12 CBK23932.2 - 1.3 8.7 6.1 6.1 6.5 0.4 2.7 1 1 1 2 2 2 0 Prefoldin subunit IncA PF04156.9 CBK23932.2 - 1.5 8.4 8.1 2.6 7.6 5.6 1.4 1 0 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 CBK23932.2 - 4 7.5 6.1 4.3 7.4 3.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 CBK23932.2 - 4.1 7.3 8.2 12 5.8 5.7 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 CBK23932.2 - 10 6.0 15.6 38 4.1 2.8 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Aa_trans PF01490.13 CBK23933.2 - 1.3e-42 145.8 33.6 1.7e-42 145.3 23.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBK23933.2 - 0.00012 21.0 28.3 0.00058 18.7 19.1 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Scs3p PF10261.4 CBK23933.2 - 0.033 13.2 4.3 0.052 12.5 0.9 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM NdhN PF11909.3 CBK23934.2 - 0.13 11.6 0.2 0.33 10.2 0.1 1.6 1 1 1 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N Choline_kinase PF01633.15 CBK23936.2 - 7.8e-06 25.6 1.1 2e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase Choline_kinase PF01633.15 CBK23937.2 - 1.4e-16 60.7 0.0 1.8e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pro_isomerase PF00160.16 CBK23938.2 - 4.1e-44 150.4 0.0 4.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Synaptobrevin PF00957.16 CBK23939.2 - 4e-27 93.6 2.5 6.6e-27 92.9 1.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBK23939.2 - 5.4e-15 54.7 0.6 9.7e-15 53.8 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Rifin_STEVOR PF02009.11 CBK23939.2 - 1.6 8.3 5.9 2.4 7.7 3.8 1.4 1 1 0 1 1 1 0 Rifin/stevor family Sigma_reg_N PF13800.1 CBK23939.2 - 2.1 8.4 4.8 43 4.2 2.3 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal NAD_synthase PF02540.12 CBK23940.2 - 7.8e-32 110.0 0.0 1.2e-31 109.4 0.0 1.3 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 CBK23940.2 - 0.083 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBK23940.2 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ctf8 PF09696.5 CBK23941.2 - 8e-14 51.4 0.0 3.2e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Ctf8 Adaptin_N PF01602.15 CBK23942.2 - 4.5e-92 309.0 1.1 5.3e-92 308.8 0.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 CBK23942.2 - 0.0039 17.1 2.4 5.9 7.2 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat Herpes_glycop PF01528.11 CBK23942.2 - 0.0066 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus glycoprotein M TIP120 PF08623.5 CBK23942.2 - 0.013 15.1 1.3 0.039 13.5 0.0 2.4 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF641 PF04859.7 CBK23942.2 - 0.099 12.4 0.2 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Cnd1 PF12717.2 CBK23942.2 - 0.11 12.3 6.4 0.17 11.7 0.2 3.4 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NAD_binding_10 PF13460.1 CBK23943.2 - 1.4e-09 38.1 0.0 2.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBK23943.2 - 1.8e-06 27.0 0.0 0.00074 18.4 0.0 2.7 2 2 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 CBK23943.2 - 0.0032 16.7 0.0 0.067 12.4 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 CBK23943.2 - 0.051 12.4 0.0 4.4 6.1 0.0 2.6 1 1 1 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 CBK23943.2 - 0.098 11.3 0.0 2 7.0 0.0 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 CBK23943.2 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase LRR_8 PF13855.1 CBK23945.2 - 0.044 13.5 0.2 7.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat ACBP PF00887.14 CBK23946.2 - 1.7e-29 101.3 0.4 1.8e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4090 PF13319.1 CBK23947.2 - 0.0094 15.8 1.0 0.012 15.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) IATP PF04568.7 CBK23947.2 - 0.019 14.9 5.2 0.026 14.5 3.5 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4460 PF14687.1 CBK23947.2 - 0.081 12.6 1.2 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Acyl_transf_1 PF00698.16 CBK23948.2 - 1.5e-10 40.9 0.0 1.9e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain RabGAP-TBC PF00566.13 CBK23949.2 - 9.7e-12 44.8 3.0 9.7e-12 44.8 2.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Uds1 PF15456.1 CBK23949.2 - 0.09 12.7 2.4 1.7 8.6 1.6 2.4 1 1 0 1 1 1 0 Up-regulated During Septation E1-E2_ATPase PF00122.15 CBK23950.2 - 1e-12 47.6 0.0 2.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CBK23950.2 - 2.6e-12 47.3 0.0 7.1e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBK23950.2 - 2.8e-09 37.7 0.3 1.4e-05 25.5 0.2 3.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK23950.2 - 9.2e-07 28.7 0.0 2.8e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK23950.2 - 0.035 13.6 0.0 0.035 13.6 0.0 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase E2F_TDP PF02319.15 CBK23951.2 - 1.9e-10 40.1 0.1 2.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Radical_SAM_N PF08497.5 CBK23951.2 - 0.063 12.2 0.0 0.069 12.0 0.0 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal HTH_38 PF13936.1 CBK23951.2 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_8 PF13855.1 CBK23952.2 - 0.0038 16.9 0.8 0.34 10.6 0.1 2.9 2 1 0 2 2 2 2 Leucine rich repeat GDI PF00996.13 CBK23953.2 - 9.4e-173 574.5 0.0 1.1e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CBK23953.2 - 0.00036 20.4 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SNF2_N PF00176.18 CBK23954.2 - 3e-63 213.3 0.0 5.6e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBK23954.2 - 7.7e-15 54.5 0.0 6.2e-14 51.6 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Thr_dehydrat_C PF00585.13 CBK23954.2 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Aldedh PF00171.17 CBK23955.2 - 5.2e-168 559.1 0.0 5.9e-168 558.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBK23955.2 - 0.17 11.0 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NIF PF03031.13 CBK23956.2 - 6.7e-50 168.8 0.0 1.3e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBK23956.2 - 0.0041 17.3 0.2 3 8.0 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase HMG_box PF00505.14 CBK23957.2 - 1.6e-23 82.7 1.6 2.6e-23 82.0 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBK23957.2 - 2e-15 56.9 0.9 3e-15 56.3 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CBK23957.2 - 0.014 15.1 0.7 0.014 15.1 0.5 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF1295 PF06966.7 CBK23959.2 - 1.3e-22 80.2 0.1 2e-22 79.6 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 CBK23959.2 - 0.00011 21.9 0.3 0.00011 21.9 0.2 2.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CBK23959.2 - 0.014 15.4 0.7 0.014 15.4 0.5 3.1 3 2 0 3 3 3 0 Phospholipid methyltransferase AzlD PF05437.7 CBK23959.2 - 0.53 10.2 11.4 1.3 9.0 0.4 3.8 3 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) ICMT PF04140.9 CBK23959.2 - 0.85 9.8 0.0 0.85 9.8 0.0 3.0 2 2 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-RING_2 PF13639.1 CBK23960.2 - 2.6e-09 36.7 10.0 2.6e-09 36.7 7.0 2.0 2 0 0 2 2 2 1 Ring finger domain zf-CCCH PF00642.19 CBK23960.2 - 4.4e-07 29.4 11.7 2.1e-05 24.0 0.3 2.9 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CBK23960.2 - 3.7e-06 26.4 7.5 9e-06 25.2 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK23960.2 - 1.1e-05 24.9 8.6 2.6e-05 23.7 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK23960.2 - 3.1e-05 23.5 9.1 9.2e-05 22.0 6.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK23960.2 - 0.0004 20.3 10.3 0.0004 20.3 7.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 CBK23960.2 - 0.00059 19.7 11.9 0.22 11.5 2.5 3.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-C3HC4_4 PF15227.1 CBK23960.2 - 0.0017 18.2 2.5 0.0017 18.2 1.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBK23960.2 - 0.0065 16.5 11.8 0.0085 16.1 7.1 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger Baculo_RING PF05883.6 CBK23960.2 - 0.023 14.5 3.9 0.045 13.5 2.7 1.6 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 CBK23960.2 - 0.29 10.9 5.9 0.32 10.7 3.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 CBK23960.2 - 0.31 10.8 7.8 0.1 12.4 3.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBK23960.2 - 0.32 10.6 8.1 1.2 8.7 5.6 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 CBK23960.2 - 3 7.3 0.0 3 7.3 0.0 2.5 3 0 0 3 3 2 0 Rad50 zinc hook motif He_PIG PF05345.7 CBK23961.2 - 3.7e-06 26.8 6.1 1.5e-05 24.8 4.2 2.1 1 0 0 1 1 1 1 Putative Ig domain TMEM154 PF15102.1 CBK23961.2 - 0.00015 21.4 2.6 0.00026 20.7 1.8 1.3 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 CBK23961.2 - 0.0012 18.5 1.7 0.0012 18.5 1.2 1.6 2 0 0 2 2 2 1 Rifin/stevor family DUF912 PF06024.7 CBK23961.2 - 0.0023 17.9 0.9 0.0045 16.9 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 CBK23961.2 - 0.0026 17.6 1.6 0.0026 17.6 1.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.1 CBK23961.2 - 0.01 16.2 1.1 0.02 15.2 0.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 CBK23961.2 - 0.011 15.0 3.2 0.023 14.0 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1510 PF07423.6 CBK23961.2 - 0.019 14.3 0.7 0.032 13.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) OAD_gamma PF04277.8 CBK23961.2 - 0.033 14.5 4.6 0.18 12.2 3.4 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Shisa PF13908.1 CBK23961.2 - 0.061 13.5 4.9 0.048 13.8 2.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.4 CBK23961.2 - 0.071 12.5 1.5 0.19 11.2 1.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1049 PF06305.6 CBK23961.2 - 0.11 12.0 0.9 0.18 11.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) OSTbeta PF15048.1 CBK23961.2 - 0.11 12.5 0.4 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein P12 PF12669.2 CBK23961.2 - 0.26 11.5 3.9 0.53 10.5 2.7 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family Peptidase_S49_N PF08496.5 CBK23961.2 - 0.29 10.9 2.3 0.47 10.2 1.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SP_C-Propep PF08999.5 CBK23961.2 - 0.32 10.5 4.7 0.68 9.4 3.2 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ASFV_J13L PF05568.6 CBK23961.2 - 1.7 8.1 11.0 0.32 10.4 4.6 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein RAMP PF04901.8 CBK23961.2 - 2.1 8.1 5.2 4 7.2 3.6 1.4 1 0 0 1 1 1 0 Receptor activity modifying family F5_F8_type_C PF00754.20 CBK23961.2 - 7.1 6.4 9.3 0.15 11.9 0.2 2.6 3 0 0 3 3 2 0 F5/8 type C domain DNA_pol_B_2 PF03175.8 CBK23962.2 - 1.2e-08 34.1 6.9 0.011 14.4 2.3 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral F_actin_bind PF08919.5 CBK23962.2 - 0.085 12.5 0.0 0.29 10.8 0.0 1.9 1 0 0 1 1 1 0 F-actin binding DUF1949 PF09186.6 CBK23963.2 - 0.0043 16.6 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) RRM_1 PF00076.17 CBK23965.2 - 1e-20 73.1 0.1 1.4e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK23965.2 - 5.7e-18 64.6 0.0 8.6e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK23965.2 - 4.9e-11 42.2 0.0 6.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK23965.2 - 0.00014 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CBK23965.2 - 0.0035 17.0 0.0 0.0081 15.8 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBK23965.2 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Macoilin PF09726.4 CBK23965.2 - 0.71 8.0 5.1 0.73 8.0 3.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Fra10Ac1 PF09725.4 CBK23966.2 - 4.1e-36 123.6 1.1 4.1e-36 123.6 0.8 1.8 2 0 0 2 2 2 1 Folate-sensitive fragile site protein Fra10Ac1 Tmemb_cc2 PF10267.4 CBK23966.2 - 0.09 11.3 13.7 0.12 10.9 9.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FAM104 PF15434.1 CBK23966.2 - 0.1 12.8 9.8 8.4 6.6 5.5 2.6 2 0 0 2 2 2 0 Family 104 Macoilin PF09726.4 CBK23966.2 - 0.88 7.7 17.1 1.2 7.3 11.9 1.1 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 CBK23966.2 - 2.3 8.5 9.5 3.2 8.0 6.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CytochromB561_N PF09786.4 CBK23966.2 - 3.6 5.9 12.8 4.9 5.4 8.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal NST1 PF13945.1 CBK23966.2 - 4.8 7.1 20.9 1.8 8.5 12.3 1.8 1 1 1 2 2 2 0 Salt tolerance down-regulator SR-25 PF10500.4 CBK23966.2 - 9.7 5.5 26.8 0.9 8.9 14.8 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Skp1 PF01466.14 CBK23968.2 - 7.4e-08 32.3 3.8 9.5e-07 28.7 2.7 2.2 1 1 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CBK23968.2 - 1.8e-05 24.7 0.5 0.00047 20.2 0.1 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain tRNA-synt_1f PF01921.13 CBK23968.2 - 0.024 13.3 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) BTB PF00651.26 CBK23968.2 - 0.029 14.3 0.5 1.6 8.7 0.3 2.3 1 1 0 1 1 1 0 BTB/POZ domain EF-hand_7 PF13499.1 CBK23969.2 - 0.00052 20.0 2.7 0.013 15.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CBK23970.2 - 0.019 14.6 0.1 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PI3_PI4_kinase PF00454.22 CBK23971.2 - 2.2e-26 92.8 0.2 3.3e-25 88.9 0.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 CBK23971.2 - 0.018 14.0 0.1 0.035 13.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) DegV PF02645.11 CBK23971.2 - 0.054 12.5 0.1 0.1 11.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 IncA PF04156.9 CBK23971.2 - 0.064 12.8 0.2 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 IncA protein DUF4206 PF13901.1 CBK23973.2 - 5.4e-31 107.7 1.7 9.2e-31 106.9 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) HC2 PF07382.6 CBK23973.2 - 3.9e-21 75.7 114.9 1.2e-06 28.5 27.5 3.8 1 1 3 4 4 4 4 Histone H1-like nucleoprotein HC2 PX PF00787.19 CBK23973.2 - 0.00028 20.6 0.0 0.00071 19.3 0.0 1.6 1 0 0 1 1 1 1 PX domain Adaptin_N PF01602.15 CBK23974.2 - 5.6e-80 269.1 1.8 7.5e-80 268.7 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK23974.2 - 2.1e-11 44.0 4.5 6.3e-08 32.6 0.1 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBK23974.2 - 4.8e-07 29.9 0.1 0.1 12.8 0.0 4.1 3 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CBK23974.2 - 4.1e-05 23.9 0.1 0.12 12.8 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 CBK23974.2 - 0.0034 17.3 3.6 5.7 7.2 0.1 4.1 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CBK23974.2 - 0.0081 16.5 2.1 0.42 11.0 0.2 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Nucleoporin_FG PF13634.1 CBK23974.2 - 0.097 12.9 84.7 0.27 11.4 26.1 3.2 1 1 1 2 2 2 0 Nucleoporin FG repeat region ParcG PF10274.4 CBK23974.2 - 0.11 12.3 0.2 3 7.7 0.0 2.4 1 1 1 2 2 2 0 Parkin co-regulated protein Lyase_1 PF00206.15 CBK23975.2 - 4e-93 312.0 0.0 7.8e-93 311.0 0.0 1.4 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.4 CBK23975.2 - 1.4e-20 73.1 0.0 4.6e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 Fumarase C C-terminus GalKase_gal_bdg PF10509.4 CBK23976.2 - 6.1e-18 63.8 0.1 1.5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CBK23976.2 - 1.3e-11 44.3 0.2 3.1e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain TBCC PF07986.7 CBK23977.2 - 2.2e-15 56.0 7.9 6.2e-15 54.6 5.5 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C SMC_N PF02463.14 CBK23979.2 - 4.5e-54 182.9 0.0 8.9e-54 182.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK23979.2 - 4e-24 84.8 0.0 1.7e-23 82.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK23979.2 - 2.5e-16 60.5 1.5 5.7e-07 29.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBK23979.2 - 8e-06 26.3 34.5 8e-06 26.3 23.9 6.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CBK23979.2 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBK23979.2 - 0.0046 16.0 1.1 0.0046 16.0 0.7 3.3 3 1 0 3 3 3 2 AAA ATPase domain DDE_Tnp_4 PF13359.1 CBK23979.2 - 0.22 11.1 4.2 2 8.0 0.1 2.8 2 0 0 2 2 2 0 DDE superfamily endonuclease PRKCSH_1 PF13015.1 CBK23980.2 - 0.0056 16.1 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein SIR2 PF02146.12 CBK23981.2 - 3.9e-39 134.1 0.0 6e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBK23981.2 - 0.013 15.2 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain OrfB_Zn_ribbon PF07282.6 CBK23981.2 - 0.11 12.2 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ogr_Delta PF04606.7 CBK23981.2 - 0.42 10.3 2.6 0.78 9.4 1.8 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger RNase_Zc3h12a PF11977.3 CBK23982.2 - 2.8e-27 95.4 0.0 3.7e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain AMP-binding PF00501.23 CBK23983.2 - 7.7e-77 258.4 0.6 9.5e-77 258.1 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.5 CBK23983.2 - 0.041 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Pkinase PF00069.20 CBK23984.2 - 1.6e-80 269.9 0.0 1.8e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK23984.2 - 2.2e-42 144.9 0.0 2.5e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK23984.2 - 2.3e-06 26.7 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK23984.2 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK23984.2 - 0.00035 19.9 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CBK23984.2 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CBK23984.2 - 0.045 13.4 0.1 0.2 11.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBK23984.2 - 0.11 12.0 2.5 0.37 10.3 1.7 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase YukC PF10140.4 CBK23984.2 - 0.19 10.2 1.5 2.7 6.4 0.0 2.0 1 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.6 CBK23984.2 - 0.28 9.9 1.7 0.65 8.7 0.1 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Polysacc_deac_1 PF01522.16 CBK23985.2 - 4.5e-11 42.4 0.6 1.2e-10 41.1 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L35Ae PF01247.13 CBK23987.2 - 2.8e-37 126.3 1.1 3.1e-37 126.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Ribosomal_L38e PF01781.13 CBK23988.2 - 2.7e-30 103.9 3.0 2.9e-30 103.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Acyltransferase PF01553.16 CBK23989.2 - 6.6e-15 54.7 0.0 1.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF4120 PF13496.1 CBK23989.2 - 0.086 12.8 0.3 6.8 6.7 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4120) SANTA PF09133.5 CBK23990.2 - 2.9e-14 52.7 0.1 5.7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 SANTA (SANT Associated) PHD PF00628.24 CBK23990.2 - 2.1e-06 27.2 7.8 5.5e-06 25.9 5.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK23990.2 - 0.00083 18.6 2.2 0.00083 18.6 1.5 2.0 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 CBK23990.2 - 0.056 12.7 6.8 0.76 9.0 2.0 2.4 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 CBK23990.2 - 2.4 8.2 7.6 5.9 6.9 5.3 1.7 1 0 0 1 1 1 0 RING-like domain CTDII PF01556.13 CBK23993.2 - 4.5e-26 90.5 1.9 6.6e-24 83.6 0.1 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CBK23993.2 - 3.2e-22 78.0 2.6 3.2e-22 78.0 1.8 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBK23993.2 - 8.8e-18 64.1 12.6 2.2e-17 62.8 8.7 1.7 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_CBB3 PF13442.1 CBK23993.2 - 0.029 14.5 5.3 1.5 9.0 0.2 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III PADR1 PF08063.7 CBK23993.2 - 2.4 7.6 11.0 1 8.8 1.4 3.1 2 1 1 3 3 3 0 PADR1 (NUC008) domain Acetyltransf_3 PF13302.1 CBK23994.2 - 2e-05 24.8 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK23994.2 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RNA_pol_Rpb1_1 PF04997.7 CBK23995.2 - 1.8e-69 234.6 0.5 3e-69 233.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CBK23995.2 - 1.2e-68 231.3 0.0 2.4e-68 230.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBK23995.2 - 2e-66 223.0 0.0 4.3e-66 221.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CBK23995.2 - 1.8e-49 168.0 1.1 1.8e-49 168.0 0.8 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CBK23995.2 - 6.9e-43 146.1 1.4 2e-42 144.6 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBK23995.2 - 1.3e-28 98.8 0.2 2.9e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 CBK23995.2 - 2.9e-23 82.0 0.0 7.9e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Baculo_PEP_C PF04513.7 CBK23995.2 - 0.0012 18.6 0.0 0.67 9.7 0.0 3.7 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSP70 PF00012.15 CBK23996.2 - 1.5e-12 46.2 0.3 9.8e-12 43.5 0.0 2.0 1 1 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 CBK23996.2 - 0.0004 19.7 0.0 0.86 8.8 0.0 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family PhoU_div PF01865.11 CBK23996.2 - 0.044 12.9 0.1 0.12 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF47 Prp19 PF08606.6 CBK23997.2 - 1.3e-34 117.7 0.8 3.1e-34 116.4 0.5 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 CBK23997.2 - 1.7e-33 113.2 0.0 1.1e-05 25.1 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat zf-Nse PF11789.3 CBK23997.2 - 8.7e-06 25.1 0.0 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.3 CBK23997.2 - 2.5e-05 22.6 3.7 0.42 8.6 0.1 3.8 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CBK23997.2 - 5.5e-05 21.6 0.0 0.45 8.7 0.0 3.2 1 1 1 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 CBK23997.2 - 0.0023 17.7 0.0 0.22 11.1 0.0 3.0 2 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A Arena_nucleocap PF00843.12 CBK23997.2 - 0.15 9.9 0.4 2.8 5.6 0.0 2.1 1 1 1 2 2 2 0 Arenavirus nucleocapsid protein Na_sulph_symp PF00939.14 CBK23998.2 - 7.1e-71 239.4 29.4 9.7e-71 239.0 20.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBK23998.2 - 5.5e-12 44.9 37.4 7.5e-07 28.0 9.8 2.3 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.7 CBK23998.2 - 0.00024 19.8 2.6 0.00024 19.8 1.8 2.6 3 0 0 3 3 3 2 DctM-like transporters Zip PF02535.17 CBK23999.2 - 6.2e-26 91.1 7.3 7.3e-26 90.9 5.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.7 CBK23999.2 - 0.023 14.2 0.0 0.023 14.2 0.0 2.0 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Bax1-I PF01027.15 CBK23999.2 - 1.2 8.7 16.6 1.8 8.1 11.4 1.3 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF204 PF02659.10 CBK23999.2 - 7 6.8 9.5 18 5.5 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF DEAD PF00270.24 CBK24000.2 - 3e-13 49.5 0.0 4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK24000.2 - 0.00038 20.3 0.0 0.0009 19.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBK24000.2 - 0.00079 19.1 0.0 0.0019 17.8 0.0 1.6 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 CBK24000.2 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBK24000.2 - 0.0084 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK24000.2 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.16 CBK24000.2 - 0.053 12.8 0.2 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_C PF00271.26 CBK24001.2 - 7.9e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XG_FTase PF03254.8 CBK24002.2 - 5.2e-05 21.9 0.0 7.3e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase NodZ PF05830.6 CBK24002.2 - 0.005 15.4 0.0 0.0065 15.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) SGS PF05002.10 CBK24002.2 - 0.021 14.5 0.1 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 SGS domain ER_lumen_recept PF00810.13 CBK24003.2 - 1.7e-31 109.6 7.1 1.7e-31 109.6 4.9 2.6 3 1 0 3 3 3 1 ER lumen protein retaining receptor DUF4234 PF14018.1 CBK24003.2 - 3.7 7.3 13.1 1.5 8.5 1.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) Fer2_3 PF13085.1 CBK24005.2 - 7.6e-33 112.6 0.0 1.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK24005.2 - 9.5e-10 38.6 6.9 9.5e-10 38.6 4.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK24005.2 - 1.3e-09 37.9 4.9 1.3e-09 37.9 3.4 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK24005.2 - 4.8e-06 26.8 3.2 4.8e-06 26.8 2.2 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK24005.2 - 0.0002 21.0 3.5 0.0002 21.0 2.4 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CBK24005.2 - 0.0003 20.4 0.4 0.0003 20.4 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 CBK24005.2 - 0.002 18.4 5.2 0.002 18.4 3.6 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK24005.2 - 0.002 18.3 12.2 0.39 11.0 0.1 3.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBK24005.2 - 3.2 8.3 8.3 2.3 8.8 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Methyltransf_11 PF08241.7 CBK24006.2 - 2e-05 25.0 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK24006.2 - 0.00021 21.6 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBK24006.2 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBK24006.2 - 0.0059 16.2 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain SAC3_GANP PF03399.11 CBK24007.2 - 8.6e-15 54.8 0.8 1.1e-14 54.4 0.6 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBK24007.2 - 2.9e-14 53.0 0.1 4.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TAP42 PF04177.7 CBK24007.2 - 0.082 11.8 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 TAP42-like family DEAD PF00270.24 CBK24008.2 - 1.5e-46 158.0 0.2 7.9e-46 155.6 0.1 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24008.2 - 1.8e-22 78.9 0.0 4.3e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBK24008.2 - 3.7e-21 74.4 0.4 7.3e-20 70.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBK24008.2 - 0.0071 16.1 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CBK24008.2 - 0.019 14.2 0.0 0.049 12.9 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain CbiG_mid PF11761.3 CBK24008.2 - 0.026 14.7 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Salt_tol_Pase PF09506.5 CBK24008.2 - 0.033 12.7 0.0 0.058 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) AAA_22 PF13401.1 CBK24008.2 - 0.23 11.6 0.9 0.97 9.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain Nop10p PF04135.7 CBK24010.2 - 3.4e-21 74.7 0.6 3.9e-21 74.5 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PBCV_basic_adap PF08789.5 CBK24010.2 - 0.14 11.8 0.7 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain zf-CCCH PF00642.19 CBK24011.2 - 4.6e-05 22.9 4.3 5.6e-05 22.7 0.8 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CART PF06373.6 CBK24011.2 - 1.4 8.9 4.6 3.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Opy2 PF09463.5 CBK24011.2 - 2.3 8.3 4.5 2.6 8.2 0.2 2.5 3 0 0 3 3 3 0 Opy2 protein zf-CCCH_2 PF14608.1 CBK24011.2 - 5.2 7.2 5.8 5.6 7.1 1.2 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S7e PF01251.13 CBK24012.2 - 5.6e-56 189.0 0.9 6.2e-56 188.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SHIPPO-rpt PF07004.7 CBK24013.2 - 4.6e-37 125.0 104.8 3.7 8.6 0.4 30.6 2 1 10 12 12 12 7 Sperm-tail PG-rich repeat Nucleoporin_FG PF13634.1 CBK24013.2 - 1.3e-29 102.6 95.1 2.1e-06 27.9 9.1 6.0 1 1 7 8 8 8 8 Nucleoporin FG repeat region DUF2738 PF10927.3 CBK24013.2 - 2.5e-13 49.6 35.2 7.5 5.5 0.0 17.4 1 1 27 28 28 28 14 Protein of unknown function (DUF2738) Ran_BP1 PF00638.13 CBK24013.2 - 5.5e-05 23.1 0.2 0.0001 22.3 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF3570 PF12094.3 CBK24013.2 - 0.00034 19.4 6.9 15 4.1 0.1 6.3 1 1 6 7 7 7 3 Protein of unknown function (DUF3570) Myb_DNA-binding PF00249.26 CBK24014.2 - 8.4e-29 99.3 4.1 3.1e-15 55.9 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK24014.2 - 2.6e-21 75.4 2.3 1.4e-13 50.6 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 CBK24014.2 - 0.088 13.0 0.2 5.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.5 CBK24014.2 - 0.09 12.5 0.2 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.1 CBK24014.2 - 0.26 11.4 4.3 3 8.0 0.7 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sec23_trunk PF04811.10 CBK24015.2 - 1e-55 188.7 0.1 1.4e-55 188.3 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 CBK24015.2 - 5e-16 57.9 3.5 1.1e-15 56.8 2.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CBK24015.2 - 1e-11 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CBK24015.2 - 5.4e-11 41.8 0.5 9.7e-11 41.0 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain VWA_2 PF13519.1 CBK24015.2 - 5.2e-07 29.9 0.1 9.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Gelsolin PF00626.17 CBK24015.2 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Nipped-B_C PF12830.2 CBK24015.2 - 0.055 13.1 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus GAS PF13851.1 CBK24016.2 - 0.0058 15.8 11.9 0.0073 15.5 8.2 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MRP-L28 PF09812.4 CBK24016.2 - 0.0067 16.2 2.9 0.0082 15.9 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 APG6 PF04111.7 CBK24016.2 - 0.0078 15.2 8.2 0.0095 15.0 5.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 ChitinaseA_N PF08329.5 CBK24016.2 - 0.018 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain LMBR1 PF04791.11 CBK24016.2 - 0.053 12.1 2.3 0.062 11.8 1.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL6 PF01763.11 CBK24016.2 - 0.065 11.3 4.6 0.078 11.1 3.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like LRS4 PF10422.4 CBK24016.2 - 0.068 12.5 2.3 0.072 12.4 1.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF2852 PF11014.3 CBK24016.2 - 0.11 12.4 2.6 0.14 12.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SlyX PF04102.7 CBK24016.2 - 0.19 12.0 5.7 8.4 6.8 2.0 2.4 2 1 0 2 2 2 0 SlyX Fib_alpha PF08702.5 CBK24016.2 - 0.48 10.5 12.1 2.6 8.1 8.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF29 PF01724.11 CBK24016.2 - 0.54 10.1 6.1 5.1 6.9 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF29 Phlebovirus_NSM PF07246.6 CBK24016.2 - 0.54 9.3 5.4 0.65 9.1 3.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_DNA_bd PF12329.3 CBK24016.2 - 0.63 9.8 9.7 3.8 7.3 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.9 CBK24016.2 - 0.64 9.9 11.4 0.9 9.4 7.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 CBK24016.2 - 0.74 7.5 3.9 0.85 7.3 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CBK24016.2 - 0.9 7.8 4.6 1.1 7.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Remorin_C PF03763.8 CBK24016.2 - 0.99 8.9 12.8 2.3 7.7 9.0 1.5 1 1 0 1 1 1 0 Remorin, C-terminal region PRP1_N PF06424.7 CBK24016.2 - 1 9.6 7.6 1.3 9.3 5.2 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3450 PF11932.3 CBK24016.2 - 1.1 8.4 10.2 2.8 7.1 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1843 PF08898.5 CBK24016.2 - 1.1 9.2 6.6 4.8 7.3 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Atg14 PF10186.4 CBK24016.2 - 1.3 7.9 6.4 1.9 7.3 4.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 CBK24016.2 - 4.2 7.1 12.8 5.6 6.7 8.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain I_LWEQ PF01608.12 CBK24016.2 - 6.5 6.6 7.7 3.5 7.5 4.1 1.4 1 1 0 1 1 1 0 I/LWEQ domain PMSR PF01625.16 CBK24017.2 - 2.5e-16 59.9 11.0 1.5e-14 54.1 7.6 2.1 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase Biotin_carb_C PF02785.14 CBK24018.2 - 0.042 13.8 3.6 1.9 8.4 0.1 3.3 2 1 1 3 3 3 0 Biotin carboxylase C-terminal domain Reo_sigmaC PF04582.7 CBK24018.2 - 0.59 9.2 19.6 0.22 10.6 3.6 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein SGT1 PF07093.6 CBK24019.2 - 7.8e-35 120.3 0.0 8.4e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 SGT1 protein Rdx PF10262.4 CBK24020.2 - 2.3e-05 24.2 0.2 3.5e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Rdx family DUF3043 PF11241.3 CBK24020.2 - 5.1 6.6 5.9 15 5.1 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Mod_r PF07200.8 CBK24021.2 - 9.4e-05 22.3 6.0 0.00015 21.6 4.2 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 CBK24021.2 - 0.00063 18.3 10.0 0.00073 18.1 6.9 1.0 1 0 0 1 1 1 1 AAA domain Syntaxin PF00804.20 CBK24021.2 - 0.00081 19.5 9.5 0.0028 17.7 6.5 1.8 1 1 0 1 1 1 1 Syntaxin Atg14 PF10186.4 CBK24021.2 - 0.0016 17.4 7.7 0.0018 17.2 5.3 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BMFP PF04380.8 CBK24021.2 - 0.0039 17.3 1.3 0.34 11.0 0.2 2.7 2 2 1 3 3 3 1 Membrane fusogenic activity SF-assemblin PF06705.6 CBK24021.2 - 0.0048 16.0 9.8 0.0097 15.0 6.8 1.3 1 1 0 1 1 1 1 SF-assemblin/beta giardin OmpH PF03938.9 CBK24021.2 - 0.006 16.5 8.8 0.01 15.7 6.1 1.4 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) FH2 PF02181.18 CBK24021.2 - 0.0061 15.4 5.5 0.4 9.5 0.1 2.1 1 1 1 2 2 2 2 Formin Homology 2 Domain Syntaxin-6_N PF09177.6 CBK24021.2 - 0.0089 16.4 6.5 0.12 12.7 0.5 2.2 1 1 1 2 2 2 1 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 CBK24021.2 - 0.0099 15.7 7.9 0.035 13.9 5.5 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_32 PF13654.1 CBK24021.2 - 0.01 14.5 3.9 0.012 14.2 2.7 1.1 1 0 0 1 1 1 0 AAA domain KAR9 PF08580.5 CBK24021.2 - 0.011 14.0 3.2 0.014 13.7 2.1 1.3 1 1 0 1 1 1 0 Yeast cortical protein KAR9 DUF1204 PF06721.6 CBK24021.2 - 0.011 14.9 1.9 0.012 14.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF812 PF05667.6 CBK24021.2 - 0.012 14.1 7.0 0.015 13.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 CBK24021.2 - 0.017 14.3 4.2 0.022 13.9 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 CBK24021.2 - 0.022 13.9 5.2 0.026 13.7 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mitofilin PF09731.4 CBK24021.2 - 0.039 12.6 9.0 0.056 12.0 6.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AKNA PF12443.3 CBK24021.2 - 0.039 13.9 2.9 0.092 12.7 0.4 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor MitMem_reg PF13012.1 CBK24021.2 - 0.054 13.5 8.6 0.42 10.7 5.0 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Apolipoprotein PF01442.13 CBK24021.2 - 0.059 12.8 6.7 0.17 11.3 4.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lipase_GDSL_3 PF14606.1 CBK24021.2 - 0.063 13.0 3.2 0.1 12.3 2.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Rootletin PF15035.1 CBK24021.2 - 0.067 13.1 6.0 0.14 12.0 3.9 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TAFH PF07531.9 CBK24021.2 - 0.068 12.8 1.2 8.9 6.0 0.3 2.4 1 1 1 2 2 2 0 NHR1 homology to TAF 4HB_MCP_1 PF12729.2 CBK24021.2 - 0.071 12.4 7.8 0.096 12.0 5.4 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Peptidase_M3 PF01432.15 CBK24021.2 - 0.074 12.0 2.1 0.1 11.5 0.7 1.6 1 1 1 2 2 2 0 Peptidase family M3 TMF_DNA_bd PF12329.3 CBK24021.2 - 0.08 12.7 10.4 2.5 7.9 0.3 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 CBK24021.2 - 0.086 12.4 8.4 0.14 11.8 5.8 1.4 1 1 0 1 1 1 0 Mnd1 family USP8_interact PF08941.5 CBK24021.2 - 0.098 11.9 2.5 0.14 11.5 1.7 1.2 1 0 0 1 1 1 0 USP8 interacting DUF4047 PF13256.1 CBK24021.2 - 0.1 12.5 5.8 0.072 13.0 2.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4047) PilJ PF13675.1 CBK24021.2 - 0.1 12.8 2.5 0.99 9.7 1.7 2.0 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term TBPIP PF07106.8 CBK24021.2 - 0.11 12.0 10.5 0.14 11.6 7.0 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RPN7 PF10602.4 CBK24021.2 - 0.11 11.8 3.4 0.2 11.0 2.0 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 IncA PF04156.9 CBK24021.2 - 0.13 11.8 2.6 0.17 11.4 1.8 1.3 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 CBK24021.2 - 0.13 12.6 10.3 2 8.8 2.0 3.0 1 1 2 3 3 3 0 Snapin/Pallidin CorA PF01544.13 CBK24021.2 - 0.15 11.0 3.0 0.35 9.8 0.5 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein FlgN PF05130.7 CBK24021.2 - 0.16 12.2 3.1 0.21 11.8 2.1 1.4 1 0 0 1 1 1 0 FlgN protein WXG100 PF06013.7 CBK24021.2 - 0.17 11.8 3.3 2 8.4 0.3 3.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF4259 PF14078.1 CBK24021.2 - 0.18 12.3 1.3 0.63 10.5 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) NAAA-beta PF15508.1 CBK24021.2 - 0.18 12.1 1.2 30 5.0 0.1 2.6 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase V_ATPase_I PF01496.14 CBK24021.2 - 0.18 9.5 5.3 0.33 8.7 3.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family hDGE_amylase PF14701.1 CBK24021.2 - 0.24 10.2 4.8 0.27 10.0 3.3 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Syntaxin_2 PF14523.1 CBK24021.2 - 0.29 11.1 9.7 0.23 11.5 4.9 2.0 1 1 1 2 2 2 0 Syntaxin-like protein Carbpep_Y_N PF05388.6 CBK24021.2 - 0.31 11.2 5.3 2.2 8.4 1.0 2.2 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Spore_III_AB PF09548.5 CBK24021.2 - 0.31 10.7 2.6 0.78 9.4 1.5 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LemA PF04011.7 CBK24021.2 - 0.32 10.0 6.2 0.55 9.3 3.8 1.8 1 1 0 1 1 1 0 LemA family Sec20 PF03908.8 CBK24021.2 - 0.32 10.7 6.3 4.6 7.0 0.0 3.0 1 1 1 2 2 2 0 Sec20 DUF2203 PF09969.4 CBK24021.2 - 0.33 11.1 5.2 4.2 7.5 3.3 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF572 PF04502.8 CBK24021.2 - 0.33 10.1 5.3 0.37 9.9 3.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Abi_C PF14355.1 CBK24021.2 - 0.35 10.8 3.3 4 7.4 0.3 3.0 1 1 3 4 4 3 0 Abortive infection C-terminus THOC7 PF05615.8 CBK24021.2 - 0.39 10.9 9.2 1.2 9.3 2.3 2.6 1 1 2 3 3 3 0 Tho complex subunit 7 DUF4446 PF14584.1 CBK24021.2 - 0.42 10.4 5.2 3.1 7.5 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) Prominin PF05478.6 CBK24021.2 - 0.43 8.0 8.3 0.45 7.9 4.5 1.5 1 1 0 1 1 1 0 Prominin DUF4164 PF13747.1 CBK24021.2 - 0.44 10.7 4.9 1.2 9.3 1.3 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) GLE1 PF07817.8 CBK24021.2 - 0.44 9.4 6.8 1.2 8.0 4.8 1.6 1 1 0 1 1 1 0 GLE1-like protein DUF4226 PF10774.4 CBK24021.2 - 0.48 10.4 4.1 8.3 6.4 1.4 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4226) DUF445 PF04286.7 CBK24021.2 - 0.48 9.9 5.6 0.68 9.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3708 PF12501.3 CBK24021.2 - 0.55 10.0 2.3 2.4 7.9 0.5 2.0 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter COG2 PF06148.6 CBK24021.2 - 0.61 9.9 6.7 3.7 7.4 4.7 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 CBK24021.2 - 0.74 10.1 8.8 1.6 9.1 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 CBK24021.2 - 0.75 9.7 9.1 2.5 8.0 0.3 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) DUF848 PF05852.6 CBK24021.2 - 0.81 9.5 6.9 0.22 11.3 1.0 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 CBK24021.2 - 0.89 9.6 12.7 0.94 9.5 7.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 CBK24021.2 - 1.5 9.1 8.8 4.8 7.5 4.4 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF1451 PF07295.6 CBK24021.2 - 1.7 8.4 7.2 2.3 7.9 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Allexi_40kDa PF05549.6 CBK24021.2 - 1.8 7.7 7.7 3.2 6.9 3.2 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3810 PF12725.2 CBK24021.2 - 1.8 7.3 4.7 2.7 6.7 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) bZIP_1 PF00170.16 CBK24021.2 - 2.6 8.0 6.2 1.5 8.8 0.1 2.7 3 1 0 3 3 2 0 bZIP transcription factor DUF2935 PF11155.3 CBK24021.2 - 3 7.9 5.2 27 4.8 3.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF16 PF01519.11 CBK24021.2 - 4.8 7.4 11.2 12 6.2 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Hemagglutinin PF00509.13 CBK24021.2 - 5.7 4.9 8.7 8.5 4.3 6.0 1.3 1 1 0 1 1 1 0 Haemagglutinin Med4 PF10018.4 CBK24021.2 - 5.9 6.2 8.6 17 4.7 5.3 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FlaC_arch PF05377.6 CBK24021.2 - 7.8 6.4 11.7 0.97 9.3 0.4 3.4 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) SNARE PF05739.14 CBK24022.2 - 2.1e-09 36.9 0.6 2.4e-09 36.7 0.4 1.2 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.13 CBK24022.2 - 8.2e-05 20.8 1.1 8.8e-05 20.7 0.8 1.0 1 0 0 1 1 1 1 Fusion glycoprotein F0 Herpes_US9 PF06072.6 CBK24022.2 - 0.0041 16.9 3.1 0.0058 16.4 2.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF912 PF06024.7 CBK24022.2 - 0.007 16.3 0.5 0.0082 16.1 0.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3753 PF12575.3 CBK24022.2 - 0.012 15.3 0.6 0.017 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Rifin_STEVOR PF02009.11 CBK24022.2 - 0.017 14.7 0.8 0.019 14.6 0.6 1.0 1 0 0 1 1 1 0 Rifin/stevor family DUF2562 PF10814.3 CBK24022.2 - 0.02 14.8 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DUF3671 PF12420.3 CBK24022.2 - 0.022 14.7 0.8 0.025 14.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2116 PF09889.4 CBK24022.2 - 0.036 13.8 0.4 0.05 13.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Scs3p PF10261.4 CBK24022.2 - 0.12 11.3 0.1 0.13 11.3 0.1 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM ETRAMP PF09716.5 CBK24022.2 - 0.13 12.2 2.7 0.19 11.7 1.9 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OppC_N PF12911.2 CBK24022.2 - 0.16 11.3 1.3 0.24 10.7 0.9 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Synaptobrevin PF00957.16 CBK24022.2 - 5.6 6.6 6.6 13 5.4 4.5 1.7 1 1 0 1 1 1 0 Synaptobrevin Ribosomal_60s PF00428.14 CBK24023.2 - 7.2e-16 58.3 15.1 8.3e-16 58.1 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3381 PF11861.3 CBK24023.2 - 0.0021 17.5 0.6 0.003 17.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Myc_N PF01056.13 CBK24023.2 - 0.023 13.8 4.5 0.025 13.7 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region AF1Q PF15017.1 CBK24023.2 - 0.034 14.0 1.5 0.043 13.7 1.1 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 CBK24023.2 - 0.085 12.3 3.6 0.099 12.1 2.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 CBK24023.2 - 0.14 11.4 7.2 0.13 11.5 5.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.3 CBK24023.2 - 0.2 11.5 6.3 0.18 11.6 4.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Shadoo PF14999.1 CBK24023.2 - 0.26 11.1 2.1 0.31 10.9 1.5 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Sigma70_ner PF04546.8 CBK24023.2 - 0.33 10.5 5.9 0.32 10.5 4.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytomega_UL84 PF06284.6 CBK24023.2 - 0.41 9.0 2.0 0.42 8.9 1.4 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein OCC1 PF15506.1 CBK24023.2 - 0.72 9.7 3.1 0.97 9.3 2.2 1.2 1 0 0 1 1 1 0 OCC1 family DUF3824 PF12868.2 CBK24023.2 - 0.73 10.7 4.2 0.9 10.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GMP_synt_C PF00958.17 CBK24024.2 - 2.9e-38 129.4 0.1 7.9e-38 128.0 0.0 1.8 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CBK24024.2 - 1.3e-35 122.6 0.1 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CBK24024.2 - 8.2e-10 37.9 0.1 9.4e-06 24.7 0.1 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CBK24024.2 - 2.5e-07 30.3 0.1 9.9e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 CBK24024.2 - 0.00079 18.0 0.3 0.0031 16.1 0.1 1.8 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 CBK24024.2 - 0.0034 16.8 0.0 0.0079 15.6 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) SNO PF01174.14 CBK24024.2 - 0.0064 16.1 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Asn_synthase PF00733.16 CBK24024.2 - 0.015 14.7 0.1 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.8 CBK24024.2 - 0.019 14.2 0.0 0.96 8.6 0.0 2.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Hexapep PF00132.19 CBK24026.2 - 4.2e-11 41.8 18.5 4.4e-07 29.1 2.0 4.1 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBK24026.2 - 2.3e-07 30.2 15.4 0.0015 18.0 2.1 3.0 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase Cation_efflux PF01545.16 CBK24027.2 - 1.1e-36 126.3 3.1 1.5e-36 125.9 2.2 1.2 1 0 0 1 1 1 1 Cation efflux family Herpes_pp38 PF04846.8 CBK24027.2 - 0.048 12.9 0.1 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein tRNA-synt_1g PF09334.6 CBK24030.2 - 7.7e-73 245.3 1.8 1.8e-72 244.1 1.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBK24030.2 - 4.4e-18 64.6 0.2 3e-13 48.6 0.2 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CBK24030.2 - 6.5e-05 22.2 0.0 0.068 12.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CBK24030.2 - 0.048 12.4 0.2 2.1 7.0 0.0 2.8 2 1 0 3 3 3 0 tRNA synthetases class I (R) He_PIG PF05345.7 CBK24031.2 - 2.7e-19 68.9 22.2 1.6e-07 31.2 2.0 4.3 3 2 0 3 3 3 3 Putative Ig domain DUF1510 PF07423.6 CBK24031.2 - 3.6e-08 33.0 11.2 7.1e-08 32.0 7.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) HRM PF02793.17 CBK24031.2 - 3.1e-06 27.1 18.3 0.00096 19.1 0.3 3.5 3 0 0 3 3 3 3 Hormone receptor domain Rifin_STEVOR PF02009.11 CBK24031.2 - 0.00036 20.2 0.9 0.00036 20.2 0.7 2.0 2 0 0 2 2 1 1 Rifin/stevor family Neur_chan_memb PF02932.11 CBK24031.2 - 0.00052 19.9 2.0 0.0012 18.8 1.4 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Cytomega_TRL10 PF06084.6 CBK24031.2 - 0.0074 16.0 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein Ycf1 PF05758.7 CBK24031.2 - 0.014 13.1 10.8 0.018 12.8 7.5 1.1 1 0 0 1 1 1 0 Ycf1 Mem_trans PF03547.13 CBK24031.2 - 0.017 13.4 2.3 0.028 12.7 1.6 1.3 1 0 0 1 1 1 0 Membrane transport protein IncA PF04156.9 CBK24031.2 - 0.021 14.4 2.5 0.051 13.1 0.5 2.1 2 0 0 2 2 2 0 IncA protein SID-1_RNA_chan PF13965.1 CBK24031.2 - 0.05 11.7 4.9 0.078 11.1 3.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.10 CBK24031.2 - 3.5 6.2 8.2 8.9 4.9 5.7 1.6 1 1 0 1 1 1 0 Serine incorporator (Serinc) AFG1_ATPase PF03969.11 CBK24032.2 - 6.9e-75 252.1 0.1 4.2e-74 249.5 0.0 1.9 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.1 CBK24032.2 - 0.00086 19.3 0.0 0.006 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 CBK24032.2 - 0.057 13.4 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.1 CBK24032.2 - 0.062 13.4 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CBK24032.2 - 0.39 10.3 4.8 3.3 7.2 0.5 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein Peptidase_C12 PF01088.16 CBK24035.2 - 1.1e-17 64.0 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3584 PF12128.3 CBK24036.2 - 0.018 12.4 11.1 0.022 12.1 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arch_flagellin PF01917.11 CBK24036.2 - 0.068 12.7 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin GIDA PF01134.17 CBK24036.2 - 0.42 9.4 3.9 0.48 9.2 2.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Galactosyl_T PF01762.16 CBK24037.2 - 1.3e-25 90.1 0.1 1.7e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CBK24037.2 - 2.5e-05 23.6 0.2 3e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Fringe-like SET_assoc PF11767.3 CBK24037.2 - 0.039 13.2 0.1 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Pam16 PF03656.8 CBK24038.2 - 1.8e-18 66.5 1.5 5.1e-18 65.0 0.5 2.2 1 1 1 2 2 2 1 Pam16 eIF3_p135 PF12807.2 CBK24039.2 - 3.8e-12 46.4 0.3 5.9e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 6PGD PF00393.14 CBK24040.2 - 1.2e-44 152.7 0.0 2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DEAD PF00270.24 CBK24040.2 - 5.3e-33 113.8 0.1 1.1e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24040.2 - 4.9e-21 74.3 0.0 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAD_binding_2 PF03446.10 CBK24040.2 - 3.9e-18 65.8 0.0 7.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CMS1 PF14617.1 CBK24040.2 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L29e PF01779.12 CBK24041.2 - 1.7e-17 62.9 8.4 1.7e-17 62.9 5.8 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family IRK PF01007.15 CBK24042.2 - 4.8e-12 45.3 0.0 5.8e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Inward rectifier potassium channel Lactamase_B PF00753.22 CBK24044.2 - 8.6e-20 71.2 0.5 1.1e-19 70.8 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBK24044.2 - 5.3e-05 22.8 0.1 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Bystin PF05291.6 CBK24045.2 - 8.2e-124 412.4 5.1 1.5e-123 411.5 3.5 1.3 1 0 0 1 1 1 1 Bystin BCDHK_Adom3 PF10436.4 CBK24045.2 - 0.13 11.7 2.7 0.27 10.7 1.9 1.6 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase zf-Tim10_DDP PF02953.10 CBK24046.2 - 1.6e-12 46.5 0.9 2.2e-12 46.0 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CBK24046.2 - 0.11 11.9 0.5 0.14 11.6 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ins_beta PF03488.9 CBK24046.2 - 0.2 11.4 1.1 0.32 10.8 0.7 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type UPF0020 PF01170.13 CBK24047.2 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBK24047.2 - 3.9e-10 39.7 0.0 6.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CBK24047.2 - 1.5e-06 27.8 0.0 4.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.10 CBK24047.2 - 0.0035 16.7 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Glyco_transf_49 PF13896.1 CBK24048.2 - 6.7e-10 38.5 0.0 0.00022 20.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan R3H PF01424.17 CBK24048.2 - 0.13 12.0 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 R3H domain TB2_DP1_HVA22 PF03134.14 CBK24049.2 - 0.0025 17.5 1.2 0.0044 16.7 0.5 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family DUF3635 PF12330.3 CBK24049.2 - 0.085 12.9 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3635) Mito_carr PF00153.22 CBK24050.2 - 4.2e-62 205.8 2.9 4e-21 74.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin_7 PF13899.1 CBK24051.2 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK24051.2 - 0.00062 19.9 0.0 0.0022 18.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBK24051.2 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin DUF792 PF05632.6 CBK24051.2 - 0.058 12.7 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) Ribosomal_L19e PF01280.15 CBK24052.2 - 4.9e-56 188.6 11.7 6.6e-56 188.1 8.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Aminotran_1_2 PF00155.16 CBK24053.2 - 1e-58 199.0 0.0 1.3e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_5 PF14501.1 CBK24053.2 - 0.0084 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Romo1 PF10247.4 CBK24053.2 - 0.012 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Cwf_Cwc_15 PF04889.7 CBK24054.2 - 0.01 15.5 0.5 0.017 14.8 0.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ufd2P_core PF10408.4 CBK24055.2 - 1.3e-16 59.9 1.0 1.7e-16 59.5 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBK24055.2 - 1e-15 57.4 0.3 2.1e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 U-box domain HAND PF09110.6 CBK24055.2 - 0.0097 16.2 1.3 0.012 16.0 0.4 1.5 2 0 0 2 2 2 1 HAND DUF3696 PF12476.3 CBK24055.2 - 0.18 11.7 1.8 0.41 10.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) Ufd2P_core PF10408.4 CBK24056.2 - 1.2e-14 53.5 6.3 1e-12 47.1 2.2 2.1 2 0 0 2 2 2 2 Ubiquitin elongating factor core Aa_trans PF01490.13 CBK24057.2 - 3.4e-47 160.8 28.9 4e-47 160.6 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma_reg_N PF13800.1 CBK24057.2 - 1.8 8.6 0.0 1.8 8.6 0.0 3.8 4 1 1 5 5 5 0 Sigma factor regulator N-terminal Dyp_perox PF04261.7 CBK24058.2 - 2.1e-53 181.0 0.0 2.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Usp PF00582.21 CBK24059.2 - 2.5e-23 82.8 0.0 7.8e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family PH PF00169.24 CBK24060.2 - 2e-07 31.1 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase PF00069.20 CBK24060.2 - 4.1e-05 22.8 0.0 8.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PH_11 PF15413.1 CBK24060.2 - 0.00022 21.4 0.3 0.00088 19.5 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBK24060.2 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_Tyr PF07714.12 CBK24060.2 - 0.02 13.9 0.0 0.08 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase PH_9 PF15410.1 CBK24060.2 - 0.13 12.4 0.2 0.59 10.2 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain TFIID_30kDa PF03540.8 CBK24061.2 - 2.1e-14 53.0 0.1 3.3e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 CBK24061.2 - 0.031 13.9 0.1 0.17 11.6 0.0 2.0 1 1 0 1 1 1 0 Bromodomain associated CSTF2_hinge PF14327.1 CBK24061.2 - 0.091 12.8 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 GTP_EFTU PF00009.22 CBK24062.2 - 8.2e-31 106.9 0.1 1.2e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBK24062.2 - 4.6e-08 33.0 0.1 2.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK24062.2 - 1.5e-06 28.1 0.1 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBK24062.2 - 0.00095 18.4 0.7 0.0083 15.3 0.5 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 CBK24062.2 - 0.0018 17.7 0.2 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.1 CBK24062.2 - 0.0043 16.6 0.1 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 CBK24062.2 - 0.0044 16.5 0.3 1.9 7.9 0.0 3.1 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF663 PF04950.7 CBK24062.2 - 0.0073 15.2 2.1 0.0082 15.1 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF663) Miro PF08477.8 CBK24062.2 - 0.055 13.9 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 Miro-like protein HMG_box PF00505.14 CBK24063.2 - 1.2e-09 38.2 2.9 2.3e-09 37.3 2.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBK24063.2 - 1e-07 32.2 3.3 1e-07 32.2 2.3 1.8 2 0 0 2 2 2 1 HMG-box domain zf-C2H2 PF00096.21 CBK24063.2 - 0.0006 19.9 9.4 0.14 12.5 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CBK24063.2 - 0.013 15.7 11.1 0.19 12.1 0.8 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBK24063.2 - 0.074 13.4 8.9 0.83 10.1 0.2 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger UNC-93 PF05978.11 CBK24064.2 - 1.5e-15 57.0 11.2 1.5e-15 57.0 7.8 3.3 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF485 PF04341.7 CBK24064.2 - 0.037 13.7 0.5 0.037 13.7 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function, DUF485 DUF1751 PF08551.5 CBK24064.2 - 0.43 10.9 10.9 0.16 12.2 1.3 3.5 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Orai-1 PF07856.7 CBK24064.2 - 2.4 7.7 10.1 2.7 7.5 5.3 2.4 2 1 0 2 2 2 0 Mediator of CRAC channel activity PTEN_C2 PF10409.4 CBK24065.2 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 CBK24065.2 - 2.5e-05 23.8 0.1 4.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 CBK24065.2 - 0.00014 21.3 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CBK24065.2 - 0.00051 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBK24065.2 - 0.0039 17.2 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 CBK24065.2 - 0.023 14.0 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBK24065.2 - 0.035 13.4 0.1 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Herpes_BLLF1 PF05109.8 CBK24065.2 - 1.1 7.1 10.3 1.6 6.6 7.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mpv17_PMP22 PF04117.7 CBK24066.2 - 3.6e-15 55.3 0.1 5.7e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family MOZART1 PF12554.3 CBK24067.2 - 8.7e-13 47.5 0.0 9.5e-13 47.4 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 CBK24067.2 - 0.00052 19.5 0.0 0.00053 19.5 0.0 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Reo_sigmaC PF04582.7 CBK24068.2 - 0.002 17.3 28.3 0.0024 17.1 8.4 3.1 1 1 2 3 3 3 2 Reovirus sigma C capsid protein DUF3851 PF12962.2 CBK24068.2 - 0.0087 16.0 2.0 0.022 14.7 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3851) YscO PF07321.7 CBK24068.2 - 0.012 15.4 18.6 0.012 15.4 12.9 5.8 1 1 4 6 6 6 0 Type III secretion protein YscO WEMBL PF05701.6 CBK24068.2 - 0.41 9.0 79.6 17 3.6 55.1 2.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 CBK24068.2 - 0.59 9.8 86.4 0.02 14.6 8.7 5.9 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 CBK24068.2 - 0.63 9.8 79.1 0.91 9.3 8.5 5.0 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CBK24068.2 - 0.91 9.0 89.1 2.2 7.8 19.0 4.3 1 1 2 3 3 3 0 IncA protein Spc7 PF08317.6 CBK24068.2 - 1.4 7.5 67.7 0.78 8.3 12.3 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein ADIP PF11559.3 CBK24068.2 - 4.1 7.3 77.0 0.82 9.5 14.9 4.8 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 CBK24069.2 - 0.0014 17.1 17.7 0.0014 17.1 12.2 3.9 1 1 3 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 CBK24069.2 - 0.071 12.2 45.8 0.42 9.7 6.1 4.6 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Sec5 PF15469.1 CBK24070.2 - 4.2e-24 85.2 5.1 4.5e-24 85.1 1.2 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 CBK24070.2 - 8.9e-09 35.0 0.5 8.9e-09 35.0 0.3 2.7 3 0 0 3 3 3 1 Vps51/Vps67 DUF2450 PF10475.4 CBK24070.2 - 1.5e-07 30.6 3.5 2e-07 30.2 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Dor1 PF04124.7 CBK24070.2 - 2e-07 29.8 3.4 3e-07 29.2 1.3 1.7 1 1 1 2 2 2 1 Dor1-like family COG2 PF06148.6 CBK24070.2 - 0.00045 20.0 7.7 0.0052 16.6 0.6 2.4 1 1 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 BBP1_C PF15272.1 CBK24070.2 - 0.026 14.0 2.4 0.059 12.9 0.0 2.5 2 1 0 3 3 3 0 Spindle pole body component BBP1, C-terminal CENP-F_leu_zip PF10473.4 CBK24070.2 - 0.093 12.5 0.3 0.093 12.5 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.4 CBK24070.2 - 0.17 11.8 3.9 1.4 8.8 0.3 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 CBK24070.2 - 0.23 10.5 3.1 0.19 10.8 0.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 CBK24070.2 - 0.67 9.7 3.1 1.1 9.0 0.2 2.4 2 1 1 3 3 3 0 Laminin Domain II Sel1 PF08238.7 CBK24072.2 - 1.4e-29 101.7 21.4 1.9e-07 31.4 0.0 9.6 10 0 0 10 10 10 8 Sel1 repeat Ank_2 PF12796.2 CBK24072.2 - 0.011 16.0 0.2 0.1 12.9 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) TPR_11 PF13414.1 CBK24072.2 - 0.11 12.1 5.5 1.6 8.4 0.2 3.5 2 1 1 3 3 3 0 TPR repeat tRNA-synt_1c PF00749.16 CBK24073.2 - 4e-103 344.3 0.0 5.8e-103 343.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBK24073.2 - 2.1e-39 134.9 0.0 3.8e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CBK24073.2 - 1.8e-21 76.3 0.3 3.6e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CBK24073.2 - 4.3e-06 27.3 5.0 1.5e-05 25.5 3.5 2.0 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FliL PF03748.9 CBK24073.2 - 0.063 13.2 0.2 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL MFS_1 PF07690.11 CBK24074.2 - 9.3e-14 50.9 4.5 1.1e-13 50.6 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF647 PF04884.9 CBK24074.2 - 0.042 13.0 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis MFS_1 PF07690.11 CBK24075.2 - 3.3e-05 22.7 2.7 3.4e-05 22.7 1.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2207 PF09972.4 CBK24075.2 - 0.029 12.9 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 CBK24075.2 - 0.039 12.5 5.4 0.054 12.0 3.8 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter YqhR PF11085.3 CBK24075.2 - 0.3 10.6 4.1 0.36 10.3 2.8 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR Bromodomain PF00439.20 CBK24076.2 - 8.1e-05 22.4 0.0 9.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Bromodomain NIF PF03031.13 CBK24078.2 - 1.4e-09 37.7 0.0 2.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HEAT PF02985.17 CBK24079.2 - 4e-06 26.4 1.1 0.0031 17.4 0.0 4.1 4 1 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 CBK24079.2 - 6.1e-05 23.3 0.0 0.39 11.2 0.0 3.1 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 CBK24079.2 - 0.00013 22.1 0.0 0.0041 17.3 0.0 2.6 2 1 1 3 3 3 2 HEAT repeats CLASP_N PF12348.3 CBK24079.2 - 0.0054 16.1 0.0 0.087 12.1 0.0 2.2 1 1 1 2 2 2 1 CLASP N terminal Adaptin_N PF01602.15 CBK24079.2 - 0.014 13.7 0.0 0.017 13.4 0.0 1.3 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.2 CBK24079.2 - 0.092 12.5 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBK24080.2 - 4.6e-07 29.3 0.5 0.15 12.2 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 CBK24080.2 - 0.00071 19.8 0.3 0.45 10.8 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats IBN_N PF03810.14 CBK24080.2 - 0.0013 18.5 0.0 0.0087 15.9 0.0 2.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CBK24080.2 - 0.0029 16.0 2.0 0.43 8.8 0.1 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Katanin_con80 PF13925.1 CBK24080.2 - 0.0035 17.0 0.1 0.0084 15.8 0.1 1.6 1 0 0 1 1 1 1 con80 domain of Katanin HEAT_EZ PF13513.1 CBK24080.2 - 0.016 15.6 4.5 6 7.4 0.1 4.4 5 1 1 6 6 6 0 HEAT-like repeat Arm PF00514.18 CBK24080.2 - 0.028 14.2 4.7 0.17 11.7 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1765 PF08578.5 CBK24080.2 - 0.071 13.1 0.5 0.33 11.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) Vac14_Fab1_bd PF12755.2 CBK24080.2 - 0.1 12.9 0.1 3.9 7.9 0.0 3.1 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 CBK24080.2 - 1.2 7.7 7.0 2.3 6.8 0.2 2.0 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal Use1 PF09753.4 CBK24081.2 - 3.2e-06 26.7 16.0 0.0011 18.4 1.9 2.0 1 1 1 2 2 2 2 Membrane fusion protein Use1 Gag_p30 PF02093.11 CBK24081.2 - 0.0059 15.8 0.9 0.028 13.6 0.1 2.1 2 0 0 2 2 2 1 Gag P30 core shell protein BAG PF02179.11 CBK24081.2 - 0.2 11.7 6.4 0.8 9.8 1.4 3.3 2 1 1 3 3 3 0 BAG domain FHIPEP PF00771.15 CBK24081.2 - 0.28 9.4 4.0 0.69 8.1 2.8 1.7 1 1 0 1 1 1 0 FHIPEP family GvpK PF05121.7 CBK24081.2 - 0.43 10.4 4.0 0.42 10.4 0.1 2.7 2 2 1 3 3 3 0 Gas vesicle protein K DASH_Dam1 PF08653.5 CBK24081.2 - 0.72 9.6 4.5 2 8.2 0.0 3.5 3 2 1 4 4 4 0 DASH complex subunit Dam1 CK_II_beta PF01214.13 CBK24081.2 - 1.3 8.4 6.8 0.14 11.6 0.6 2.1 2 1 0 2 2 2 0 Casein kinase II regulatory subunit ISG65-75 PF11727.3 CBK24081.2 - 2.5 7.0 8.3 0.28 10.2 1.7 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein Cauli_AT PF03233.8 CBK24081.2 - 2.7 7.6 13.5 4.3 7.0 3.0 2.2 2 0 0 2 2 2 0 Aphid transmission protein Spore_II_R PF09551.5 CBK24081.2 - 6.1 6.8 7.7 1.2 9.1 0.5 2.6 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) Ribosomal_L18e PF00828.14 CBK24082.2 - 2.1e-31 109.0 0.0 3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosom_S12_S23 PF00164.20 CBK24083.2 - 1.2e-37 128.0 1.7 1.5e-37 127.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nucleotid_trans PF03407.11 CBK24084.2 - 6.2e-23 81.6 0.1 9.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Ribonuc_L-PSP PF01042.16 CBK24085.2 - 1.1e-42 144.6 0.1 1.3e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.1 CBK24085.2 - 0.02 14.8 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease PPR_2 PF13041.1 CBK24086.2 - 5.5e-23 80.6 0.1 1.5e-11 44.0 0.0 4.5 2 1 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 CBK24086.2 - 2.6e-19 67.7 0.1 6.6e-06 25.9 0.0 5.7 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.15 CBK24086.2 - 8.7e-16 56.7 2.7 3.7e-07 29.6 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 CBK24086.2 - 4.2e-14 51.7 0.0 2.3e-07 30.1 0.0 3.7 3 0 0 3 3 3 3 PPR repeat TPR_19 PF14559.1 CBK24086.2 - 0.035 14.4 0.1 1.6 9.1 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24086.2 - 0.074 13.0 0.5 0.98 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 CBK24087.2 - 5.7e-21 74.6 0.0 7.7e-14 51.8 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBK24087.2 - 1.9e-20 71.5 1.6 3e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CBK24087.2 - 1.1e-19 68.5 2.4 4.8e-05 23.1 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBK24087.2 - 6e-17 61.2 3.3 5e-06 26.5 0.1 3.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBK24087.2 - 6.6e-16 58.3 1.1 4.9e-08 33.2 0.0 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) HTH_18 PF12833.2 CBK24087.2 - 0.04 14.0 0.1 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.18 CBK24087.2 - 0.13 12.0 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family UQ_con PF00179.21 CBK24088.2 - 7.3e-30 103.2 0.1 9.4e-30 102.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBK24088.2 - 0.00041 20.2 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Kinesin PF00225.18 CBK24090.2 - 1.4e-68 231.0 0.3 1.4e-68 231.0 0.2 3.9 4 1 1 5 5 5 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBK24090.2 - 2.5 7.1 50.7 0.056 12.6 5.3 6.0 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Cation_efflux PF01545.16 CBK24091.2 - 3.4e-16 59.1 0.0 4.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family XFP_N PF09364.5 CBK24091.2 - 0.088 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain SNARE PF05739.14 CBK24092.2 - 8.9e-11 41.3 6.2 8.9e-11 41.3 4.3 2.3 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 CBK24092.2 - 1.4e-06 27.9 4.9 2.1e-06 27.3 3.4 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4239 PF14023.1 CBK24092.2 - 0.00062 19.1 3.8 0.0011 18.3 2.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF4239) ASD2 PF08687.6 CBK24092.2 - 0.0088 15.3 3.9 0.012 14.9 2.7 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Syntaxin-6_N PF09177.6 CBK24092.2 - 0.039 14.3 11.9 0.049 14.0 0.4 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF812 PF05667.6 CBK24092.2 - 0.041 12.4 8.2 0.051 12.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-Q PF13094.1 CBK24092.2 - 0.087 12.8 10.0 0.12 12.4 6.9 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF445 PF04286.7 CBK24092.2 - 0.1 12.1 6.9 0.13 11.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DHquinase_I PF01487.10 CBK24092.2 - 0.1 12.2 1.9 0.21 11.2 0.0 2.2 1 1 2 3 3 3 0 Type I 3-dehydroquinase Polyhedrin PF00738.13 CBK24092.2 - 0.14 11.2 0.7 0.19 10.8 0.5 1.3 1 1 0 1 1 1 0 Polyhedrin Baculo_p24 PF05073.7 CBK24092.2 - 0.2 11.2 2.5 0.27 10.7 1.8 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Sec2p PF06428.6 CBK24092.2 - 0.24 11.2 7.8 0.3 10.9 4.6 1.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.5 CBK24092.2 - 0.27 11.3 7.8 0.37 10.8 5.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 CBK24092.2 - 0.58 9.9 6.0 1.1 8.9 0.9 2.1 1 1 0 2 2 2 0 Laminin Domain II CorA PF01544.13 CBK24092.2 - 0.75 8.7 8.2 1.2 8.1 5.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF745 PF05335.8 CBK24092.2 - 0.88 9.0 4.8 1.7 8.1 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Sec34 PF04136.10 CBK24092.2 - 0.9 9.2 4.9 1.7 8.3 1.5 2.2 1 1 1 2 2 2 0 Sec34-like family FliJ PF02050.11 CBK24092.2 - 1.2 9.1 13.7 1.6 8.7 0.3 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Ly49 PF08391.5 CBK24092.2 - 2.9 8.0 4.8 6.9 6.8 0.2 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF1664 PF07889.7 CBK24092.2 - 4.9 6.9 7.1 1.5 8.6 1.9 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 CBK24092.2 - 5.9 7.3 6.6 3.4 8.1 1.3 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 CBK24092.2 - 8.9 5.8 13.5 0.25 10.9 2.4 2.0 1 1 0 2 2 2 0 IncA protein NUC173 PF08161.7 CBK24093.2 - 6.9e-25 87.5 0.0 2.4e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 NUC173 domain DPM2 PF07297.7 CBK24093.2 - 0.022 15.0 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GTP_EFTU PF00009.22 CBK24094.2 - 1.1e-46 158.7 0.1 3.1e-46 157.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBK24094.2 - 1e-23 82.9 0.1 3.2e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBK24094.2 - 1.8e-07 31.1 0.4 3.6e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CBK24094.2 - 0.00034 20.1 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBK24094.2 - 0.0099 15.7 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus T2SM_b PF10741.4 CBK24094.2 - 0.022 14.3 0.1 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b AIG1 PF04548.11 CBK24094.2 - 0.031 13.3 0.0 0.081 12.0 0.0 1.7 1 0 0 1 1 1 0 AIG1 family LRR_4 PF12799.2 CBK24095.2 - 2.3e-07 30.2 1.6 0.011 15.3 0.0 4.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK24095.2 - 0.00022 20.9 4.3 0.27 10.9 0.1 4.0 4 0 0 4 4 4 2 Leucine rich repeat tRNA-synt_1 PF00133.17 CBK24096.2 - 7.6e-148 493.1 0.1 1.1e-147 492.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBK24096.2 - 9.7e-31 106.5 0.2 1.7e-30 105.7 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBK24096.2 - 4.7e-17 61.7 0.2 1.8e-08 33.4 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CBK24096.2 - 9.9e-05 21.7 0.0 0.00023 20.4 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 CBK24096.2 - 0.011 14.9 0.0 0.33 10.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UCH PF00443.24 CBK24097.2 - 1.4e-16 60.4 1.5 1.5e-16 60.3 0.8 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24097.2 - 0.0013 18.2 2.1 0.0018 17.7 1.5 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 CBK24098.2 - 2e-25 89.4 1.8 8.1e-25 87.4 1.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24098.2 - 6.5e-09 35.6 0.2 1.2e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase tRNA_anti_2 PF13742.1 CBK24098.2 - 0.11 12.3 1.4 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain ECH PF00378.15 CBK24099.2 - 2.6e-24 85.6 0.0 3.1e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CPSase_L_D2 PF02786.12 CBK24100.2 - 1.1e-53 181.6 0.0 2.9e-53 180.3 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK24100.2 - 2.9e-38 130.3 0.0 5.3e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CBK24100.2 - 2.9e-15 55.8 0.0 7.1e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBK24100.2 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK24100.2 - 1.2e-07 31.2 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK24100.2 - 0.0011 18.3 0.0 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_N PF02844.10 CBK24100.2 - 0.15 12.5 0.1 2.5 8.6 0.0 2.9 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain Biotin_lipoyl PF00364.17 CBK24101.2 - 2.6e-16 59.0 0.8 3.2e-16 58.7 0.6 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBK24101.2 - 2.5e-07 30.2 0.1 2.1e-05 24.0 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 CBK24101.2 - 0.00023 20.4 0.0 0.00067 18.9 0.0 1.7 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CBK24101.2 - 0.00067 19.9 0.0 0.045 14.0 0.0 2.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 CBK24101.2 - 0.00075 18.8 0.1 0.001 18.4 0.0 1.2 1 1 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.1 CBK24101.2 - 0.012 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 CBK24101.2 - 0.017 14.7 0.1 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_S24 PF00717.18 CBK24101.2 - 0.039 13.5 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase S24-like PYNP_C PF07831.8 CBK24101.2 - 0.044 13.2 0.1 0.095 12.1 0.1 1.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.6 CBK24101.2 - 0.083 12.0 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Mob1_phocein PF03637.12 CBK24102.2 - 3.7e-50 170.0 0.2 4.3e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family TMEM213 PF15192.1 CBK24102.2 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TMEM213 family Mei4 PF13971.1 CBK24102.2 - 0.11 11.3 0.0 0.35 9.7 0.0 1.7 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 TPR_12 PF13424.1 CBK24103.2 - 2.7e-16 59.2 4.4 5.6e-13 48.6 1.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBK24103.2 - 8.7e-14 50.9 3.1 8.1e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBK24103.2 - 5.9e-08 31.9 8.2 9.6e-08 31.3 1.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK24103.2 - 2.6e-07 30.1 3.0 2.6e-07 30.1 2.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBK24103.2 - 9e-07 28.3 6.5 5.9e-06 25.7 0.6 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK24103.2 - 3.3e-05 23.3 1.2 0.00026 20.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK24103.2 - 0.00022 20.7 2.2 0.00022 20.7 1.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.4 CBK24103.2 - 0.0012 18.3 0.9 0.0014 18.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.1 CBK24103.2 - 0.011 16.4 1.5 0.045 14.4 1.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBK24103.2 - 0.013 16.0 0.6 0.66 10.7 0.0 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ENTH PF01417.15 CBK24103.2 - 0.042 13.7 0.1 0.071 12.9 0.0 1.6 1 1 0 1 1 1 0 ENTH domain DUF4404 PF14357.1 CBK24103.2 - 0.094 13.1 0.1 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_6 PF13174.1 CBK24103.2 - 0.71 10.4 2.7 0.75 10.3 0.5 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat HECT PF00632.20 CBK24104.2 - 1.9e-62 211.2 0.6 5.7e-62 209.7 0.0 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Big_3_2 PF12245.3 CBK24104.2 - 0.063 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Thioredoxin PF00085.15 CBK24105.2 - 2.2e-20 72.2 0.0 3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBK24105.2 - 5.2e-06 26.3 0.0 1.3e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK24105.2 - 7.2e-06 26.1 0.1 0.00013 22.0 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK24105.2 - 0.07 13.2 0.2 4.2 7.5 0.1 2.4 1 1 1 2 2 2 0 Thioredoxin-like AAA_5 PF07728.9 CBK24106.2 - 1.3e-54 183.7 0.0 1.7e-13 50.4 0.0 7.4 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBK24106.2 - 4.6e-15 55.9 0.7 0.0094 16.0 0.0 6.5 6 2 0 6 6 5 3 AAA domain AAA_14 PF13173.1 CBK24106.2 - 3.1e-14 52.9 0.0 0.0088 15.9 0.0 6.3 5 0 0 5 5 5 3 AAA domain AAA_3 PF07726.6 CBK24106.2 - 2.1e-12 46.7 0.0 2.7e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBK24106.2 - 3.3e-08 33.1 0.0 0.0046 16.4 0.0 4.6 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA PF00004.24 CBK24106.2 - 1.1e-05 25.5 0.6 1.1 9.5 0.0 5.5 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBK24106.2 - 2.3e-05 24.3 0.0 0.12 12.2 0.0 4.6 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CBK24106.2 - 4.3e-05 23.5 0.4 1.4 8.9 0.0 4.7 5 0 0 5 5 5 1 AAA ATPase domain VWA_2 PF13519.1 CBK24106.2 - 0.00067 19.7 0.1 0.0078 16.3 0.0 2.8 4 0 0 4 4 3 1 von Willebrand factor type A domain ABC_tran PF00005.22 CBK24106.2 - 0.026 14.8 4.7 5.3 7.3 0.0 4.5 4 0 0 4 4 3 0 ABC transporter AAA_17 PF13207.1 CBK24106.2 - 0.046 14.5 3.3 12 6.7 0.0 5.8 6 1 0 6 6 4 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK24106.2 - 0.046 13.1 0.1 15 4.9 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CBK24106.2 - 0.074 12.6 0.0 17 4.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 CBK24106.2 - 0.14 11.6 0.0 12 5.5 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBK24106.2 - 0.26 11.0 0.0 59 3.5 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain D-aminoacyl_C PF07908.7 CBK24106.2 - 2.5 7.4 0.0 5.6 6.3 0.0 1.6 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region KfrA_N PF11740.3 CBK24106.2 - 3 8.3 1.4 6.7 7.1 1.0 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Hydrolase PF00702.21 CBK24107.2 - 5.1e-11 43.4 0.2 1.1e-09 39.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK24107.2 - 9.7e-07 29.1 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBK24107.2 - 0.072 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK24107.2 - 0.086 12.4 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pox_P35 PF03213.9 CBK24107.2 - 2.2 7.1 6.6 3.3 6.6 4.6 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein E1-E2_ATPase PF00122.15 CBK24108.2 - 7.1e-14 51.4 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase PHD PF00628.24 CBK24109.2 - 2.4e-07 30.3 4.5 2.4e-07 30.3 3.1 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBK24109.2 - 5.3e-05 23.1 0.3 9.8e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBK24109.2 - 0.0002 21.4 1.8 0.00044 20.3 1.3 1.7 1 1 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.17 CBK24109.2 - 0.13 12.0 3.3 0.16 11.7 0.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC_5 PF14787.1 CBK24109.2 - 0.16 11.4 1.1 0.41 10.1 0.7 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger cEGF PF12662.2 CBK24109.2 - 0.16 11.6 1.1 0.53 9.9 0.8 1.9 1 0 0 1 1 1 0 Complement Clr-like EGF-like zf-RING_2 PF13639.1 CBK24109.2 - 0.79 9.6 10.0 0.34 10.7 5.2 1.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_3 PF14369.1 CBK24109.2 - 1.2 9.2 4.9 1.2 9.1 1.4 2.2 2 0 0 2 2 2 0 zinc-finger zf-rbx1 PF12678.2 CBK24109.2 - 1.9 8.6 4.8 6.7 6.8 3.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 CBK24109.2 - 8.9 6.1 8.3 64 3.3 6.1 2.1 1 1 1 2 2 2 0 zinc-RING finger domain RRM_1 PF00076.17 CBK24110.2 - 1.8e-24 85.1 0.1 4.8e-20 70.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24110.2 - 1.9e-17 62.9 0.0 2.8e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24110.2 - 2.6e-07 30.3 0.2 6.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK24110.2 - 0.029 14.2 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif MSP1_C PF07462.6 CBK24110.2 - 8.9 4.5 6.7 13 4.0 4.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cyclin_N PF00134.18 CBK24111.2 - 5.9e-17 61.4 0.0 1.3e-16 60.3 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cpn60_TCP1 PF00118.19 CBK24112.2 - 2.3e-129 432.2 13.2 2.6e-129 432.0 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 CBK24112.2 - 0.2 11.3 1.6 0.51 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) RRM_6 PF14259.1 CBK24113.2 - 9.1e-09 35.1 0.0 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK24113.2 - 0.00043 19.9 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CBK24113.2 - 0.00047 19.9 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK24113.2 - 0.0015 18.0 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK24113.2 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Viral_NABP PF05515.6 CBK24113.2 - 0.084 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral nucleic acid binding ING PF12998.2 CBK24113.2 - 0.12 12.7 0.4 0.43 10.8 0.2 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Hid1 PF12722.2 CBK24114.2 - 2.4 5.7 20.0 3.2 5.2 13.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec7_N PF12783.2 CBK24115.2 - 6.5e-29 100.5 4.2 6.5e-29 100.5 2.9 2.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4175 PF13779.1 CBK24115.2 - 1.2 6.7 4.0 1.7 6.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SMC_N PF02463.14 CBK24116.2 - 1.8e-78 262.7 8.4 6.6e-78 260.9 5.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK24116.2 - 1.2e-22 80.1 0.0 3.9e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK24116.2 - 4.1e-16 59.8 8.9 5.2e-08 33.1 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBK24116.2 - 5.3e-07 30.1 32.0 5.3e-07 30.1 22.2 6.1 2 2 2 4 4 2 1 AAA domain AAA_29 PF13555.1 CBK24116.2 - 1.5e-06 27.5 0.0 3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CBK24116.2 - 8.3e-05 21.9 16.7 0.004 16.3 0.3 4.7 2 2 3 5 5 5 3 Reovirus sigma C capsid protein IncA PF04156.9 CBK24116.2 - 0.00018 21.1 8.1 0.00018 21.1 5.6 7.6 4 2 2 6 6 6 1 IncA protein Tropomyosin_1 PF12718.2 CBK24116.2 - 0.0027 17.5 13.0 0.0027 17.5 9.0 6.4 2 2 4 6 6 3 2 Tropomyosin like ABC_tran PF00005.22 CBK24116.2 - 0.091 13.0 0.0 0.091 13.0 0.0 6.3 3 2 0 3 3 2 0 ABC transporter Baculo_PEP_C PF04513.7 CBK24116.2 - 0.13 12.0 17.7 0.26 11.0 0.1 5.1 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SecD-TM1 PF13721.1 CBK24116.2 - 1.1 9.5 9.6 1.1 9.5 3.7 3.2 2 1 1 3 3 3 0 SecD export protein N-terminal TM region Carn_acyltransf PF00755.15 CBK24117.2 - 0.015 13.4 0.1 0.015 13.4 0.1 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase RBFA PF02033.13 CBK24117.2 - 0.18 11.8 0.5 1.6 8.7 0.0 2.0 1 1 1 2 2 2 0 Ribosome-binding factor A Beach PF02138.13 CBK24118.2 - 3.4e-80 269.3 0.0 4.4e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Herpes_gE PF02480.11 CBK24120.2 - 0.021 13.0 3.2 0.022 13.0 0.0 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E LSR PF05624.9 CBK24120.2 - 0.025 14.3 3.2 0.038 13.7 2.3 1.2 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) IncA PF04156.9 CBK24120.2 - 0.034 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein FAM176 PF14851.1 CBK24120.2 - 0.07 12.8 0.0 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 FAM176 family Tweety PF04906.8 CBK24120.2 - 0.091 11.1 0.5 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 CBK24120.2 - 0.58 10.3 21.9 5.5 7.1 12.0 2.8 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator L51_S25_CI-B8 PF05047.11 CBK24121.2 - 5.8e-10 38.7 0.3 9.9e-10 38.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Adap_comp_sub PF00928.16 CBK24123.2 - 2.1e-82 276.2 0.0 2.6e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK24123.2 - 2.9e-09 36.7 0.2 5.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.18 CBK24124.2 - 2.2e-66 223.6 0.1 3.6e-66 222.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-HC5HC2H_2 PF13832.1 CBK24124.2 - 1.5e-21 76.4 7.6 1.5e-21 76.4 5.3 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBK24124.2 - 2.3e-17 62.8 3.4 2.3e-17 62.8 2.4 2.4 2 1 1 3 3 3 1 PHD-like zinc-binding domain Helicase_C PF00271.26 CBK24124.2 - 2.6e-14 52.8 0.1 7.9e-14 51.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBK24124.2 - 3.1e-06 26.2 0.1 1.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD_2 PF13831.1 CBK24124.2 - 4.2e-06 25.9 9.7 4.2e-06 25.9 6.7 2.7 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 CBK24124.2 - 0.0013 18.3 15.4 0.0013 18.3 10.6 2.9 3 0 0 3 3 3 1 PHD-finger DEAD PF00270.24 CBK24124.2 - 0.0023 17.4 0.0 0.0072 15.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK24124.2 - 0.0024 18.0 0.1 0.017 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain Sigma_reg_N PF13800.1 CBK24125.2 - 0.023 14.7 1.2 0.054 13.5 0.8 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EGF_2 PF07974.8 CBK24125.2 - 0.073 13.2 11.7 0.21 11.7 8.1 1.9 1 0 0 1 1 1 0 EGF-like domain RAMP4 PF06624.7 CBK24127.2 - 3.6e-13 48.8 0.1 6.4e-13 48.0 0.0 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 RtcB PF01139.12 CBK24128.2 - 2.9e-140 467.9 0.0 3.4e-140 467.7 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cytochrom_c3_2 PF14537.1 CBK24128.2 - 0.059 13.7 0.2 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c3 CitX PF03802.9 CBK24128.2 - 0.49 9.7 3.2 1 8.7 2.2 1.5 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Pro_isomerase PF00160.16 CBK24129.2 - 6.9e-29 101.0 0.1 6.9e-29 101.0 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zip PF02535.17 CBK24129.2 - 0.01 14.8 5.1 0.011 14.7 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Strabismus PF06638.6 CBK24129.2 - 0.3 9.3 4.7 0.4 8.9 3.3 1.1 1 0 0 1 1 1 0 Strabismus protein CDC45 PF02724.9 CBK24129.2 - 1.3 6.9 7.7 1.6 6.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.9 CBK24129.2 - 1.5 8.1 12.9 2 7.7 8.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Med7 PF05983.6 CBK24130.2 - 6.2e-07 29.3 0.3 7.4e-07 29.0 0.2 1.0 1 0 0 1 1 1 1 MED7 protein FYVE PF01363.16 CBK24131.2 - 4.4e-16 58.5 7.0 9.1e-16 57.5 4.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 CBK24131.2 - 0.004 17.0 3.9 0.0096 15.7 2.7 1.7 1 0 0 1 1 1 1 IBR domain GAS PF13851.1 CBK24131.2 - 0.0044 16.2 20.7 0.0044 16.2 14.4 1.8 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 CBK24131.2 - 0.017 14.6 23.8 0.023 14.2 16.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family COQ7 PF03232.8 CBK24131.2 - 0.029 13.8 7.5 0.032 13.7 4.6 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF4201 PF13870.1 CBK24131.2 - 0.038 13.4 19.4 0.074 12.4 13.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Striatin PF08232.7 CBK24131.2 - 0.077 13.3 19.8 0.18 12.1 13.7 1.7 1 1 0 1 1 1 0 Striatin family THP2 PF09432.5 CBK24131.2 - 0.13 12.1 8.9 0.21 11.4 5.9 1.5 1 1 0 1 1 1 0 Tho complex subunit THP2 V_ATPase_I PF01496.14 CBK24131.2 - 0.55 8.0 8.9 0.67 7.7 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 CBK24131.2 - 0.61 9.7 18.8 1.1 8.8 13.0 1.4 1 0 0 1 1 1 0 Mnd1 family Reo_sigmaC PF04582.7 CBK24131.2 - 1 8.4 6.0 0.69 9.0 2.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4349 PF14257.1 CBK24131.2 - 1.6 7.8 11.2 3.1 6.9 6.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) CENP-H PF05837.7 CBK24131.2 - 2 8.6 19.0 0.49 10.5 10.4 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1993 PF09351.5 CBK24131.2 - 2.1 8.2 8.1 3.2 7.6 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Seryl_tRNA_N PF02403.17 CBK24131.2 - 2.3 8.2 21.1 0.3 11.1 10.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CBK24131.2 - 2.3 7.1 21.4 4.1 6.3 14.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 CBK24131.2 - 2.9 6.4 17.4 5.6 5.5 12.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 CBK24131.2 - 4 7.4 14.5 1.3 9.0 1.2 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) HypA PF01155.14 CBK24131.2 - 5.1 6.8 11.4 0.52 10.0 3.0 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1049 PF06305.6 CBK24131.2 - 6.1 6.4 6.4 9 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3735 PF12537.3 CBK24131.2 - 7.7 6.6 5.9 13 5.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) Pox_A_type_inc PF04508.7 CBK24131.2 - 8.2 6.5 6.9 8.4 6.4 0.1 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat ADIP PF11559.3 CBK24131.2 - 8.3 6.2 25.6 7.8 6.3 5.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 CBK24131.2 - 8.8 6.0 18.5 2.5 7.8 5.4 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 CBK24131.2 - 9.8 6.0 32.2 0.52 10.1 12.3 3.0 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding HC2 PF07382.6 CBK24132.2 - 0.072 12.9 52.6 2.8 7.7 14.6 3.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 tRNA-synt_1 PF00133.17 CBK24133.2 - 8.1e-135 450.1 0.0 4.9e-131 437.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBK24133.2 - 1.2e-15 57.0 1.2 8.9e-08 31.1 0.1 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CBK24133.2 - 0.0013 18.1 0.0 1.8 7.8 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.8 CBK24133.2 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CBK24133.2 - 0.11 11.6 0.0 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CBK24133.2 - 0.18 10.5 0.1 2.7 6.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 CBK24133.2 - 0.3 9.7 2.0 5.2 5.6 0.2 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain MORN PF02493.15 CBK24134.2 - 0.035 13.8 0.0 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 MORN repeat LRR_5 PF13306.1 CBK24134.2 - 0.036 13.7 16.7 0.06 13.0 0.2 4.6 2 1 0 4 4 4 0 Leucine rich repeats (6 copies) ABC_tran PF00005.22 CBK24135.2 - 9.7e-73 242.9 1.0 8.1e-37 126.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CBK24135.2 - 1.2e-44 152.8 8.7 7.2e-24 84.6 0.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CBK24135.2 - 3.2e-17 63.4 0.7 0.02 14.8 0.0 5.2 3 2 1 5 5 5 4 AAA domain AAA_16 PF13191.1 CBK24135.2 - 1.1e-12 48.2 0.0 8.8e-06 25.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBK24135.2 - 5.2e-11 42.8 2.8 0.00057 20.0 0.3 4.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK24135.2 - 2.6e-09 36.4 0.0 0.0019 17.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBK24135.2 - 4.2e-09 36.0 0.9 0.14 11.5 0.0 4.0 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 CBK24135.2 - 4.9e-09 35.7 7.8 0.0049 16.1 0.0 4.4 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBK24135.2 - 4.9e-09 35.5 0.3 0.0042 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK24135.2 - 1e-08 36.0 0.0 0.0071 17.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CBK24135.2 - 1e-07 30.9 1.9 0.0013 17.4 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA PF00004.24 CBK24135.2 - 1.2e-07 31.9 1.6 0.0017 18.5 0.0 4.3 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CBK24135.2 - 1.5e-07 31.2 3.8 0.0026 17.6 0.5 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CBK24135.2 - 3.1e-07 30.7 0.4 0.01 16.1 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.1 CBK24135.2 - 6.4e-07 29.1 0.6 0.15 11.6 0.1 4.6 3 2 1 4 4 4 2 AAA domain AAA_10 PF12846.2 CBK24135.2 - 8.5e-07 28.6 3.4 0.14 11.5 0.1 4.3 4 0 0 4 4 4 1 AAA-like domain AAA_5 PF07728.9 CBK24135.2 - 4.4e-06 26.4 0.8 1.1 8.9 0.0 4.7 5 0 0 5 5 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBK24135.2 - 7.1e-06 26.1 0.1 0.22 11.7 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_23 PF13476.1 CBK24135.2 - 2e-05 24.9 8.4 0.018 15.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 CBK24135.2 - 7.7e-05 22.4 0.1 0.66 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CBK24135.2 - 8.2e-05 21.4 8.5 0.014 14.0 0.0 3.0 3 0 0 3 3 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CBK24135.2 - 0.00011 22.1 0.1 0.46 10.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase NB-ARC PF00931.17 CBK24135.2 - 0.00027 19.9 0.2 0.14 11.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 CBK24135.2 - 0.00029 20.7 0.2 0.46 10.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK24135.2 - 0.00036 20.2 0.3 1.1 9.0 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain PRK PF00485.13 CBK24135.2 - 0.00071 19.1 0.2 0.65 9.5 0.1 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CBK24135.2 - 0.00082 19.8 0.0 0.24 11.8 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein IstB_IS21 PF01695.12 CBK24135.2 - 0.0011 18.4 0.8 6.3 6.1 0.0 4.1 5 0 0 5 5 4 0 IstB-like ATP binding protein ArgK PF03308.11 CBK24135.2 - 0.0017 17.2 0.0 0.31 9.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 CBK24135.2 - 0.0019 17.3 0.0 0.53 9.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.11 CBK24135.2 - 0.0024 17.1 0.1 1.8 7.7 0.0 3.3 3 0 0 3 3 3 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 CBK24135.2 - 0.0028 17.1 0.0 0.08 12.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 CBK24135.2 - 0.0031 17.0 0.1 4.3 6.7 0.0 3.4 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBK24135.2 - 0.004 17.0 0.0 3.5 7.5 0.0 3.3 4 0 0 4 4 2 0 AAA domain Rad17 PF03215.10 CBK24135.2 - 0.004 15.8 0.0 0.24 10.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 CBK24135.2 - 0.0049 16.4 0.5 0.55 9.7 0.0 2.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 CBK24135.2 - 0.0058 15.8 0.0 0.41 9.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBK24135.2 - 0.0097 15.5 0.2 1.3 8.6 0.1 2.9 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 CBK24135.2 - 0.012 15.6 0.0 8.5 6.4 0.0 3.5 3 0 0 3 3 3 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 CBK24135.2 - 0.016 14.2 0.0 0.42 9.5 0.0 3.2 4 1 0 4 4 4 0 KAP family P-loop domain ATP-synt_ab PF00006.20 CBK24135.2 - 0.02 14.3 0.1 3.1 7.2 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 CBK24135.2 - 0.024 13.5 0.1 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 CBK24135.2 - 0.032 13.8 0.1 2.7 7.6 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 CBK24135.2 - 0.071 13.0 0.2 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CBK24135.2 - 0.075 12.8 7.1 0.17 11.6 0.0 3.1 3 1 0 3 3 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 CBK24135.2 - 0.1 11.6 8.8 0.14 11.2 0.0 3.6 5 0 0 5 5 4 0 AAA ATPase domain He_PIG PF05345.7 CBK24137.2 - 0.0022 17.9 0.5 0.0022 17.9 0.3 3.4 3 0 0 3 3 3 1 Putative Ig domain F5_F8_type_C PF00754.20 CBK24137.2 - 0.16 11.8 19.3 0.065 13.0 1.8 4.2 4 0 0 4 4 4 0 F5/8 type C domain DUF563 PF04577.9 CBK24139.2 - 8.7e-17 61.7 0.2 1.8e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SPX PF03105.14 CBK24140.2 - 1.5e-24 87.2 4.8 4.3e-14 52.9 0.0 2.6 1 1 1 2 2 2 2 SPX domain IGR PF09597.5 CBK24140.2 - 0.013 15.3 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 IGR protein motif PLU-1 PF08429.6 CBK24140.2 - 0.056 12.3 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 PLU-1-like protein FliJ PF02050.11 CBK24140.2 - 0.072 13.1 2.1 0.66 10.0 0.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein EXS PF03124.9 CBK24141.2 - 2.7e-49 168.0 13.7 2.4e-48 164.9 9.5 1.9 1 1 0 1 1 1 1 EXS family DUF805 PF05656.9 CBK24141.2 - 0.46 10.3 3.9 1.4 8.7 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) NACHT PF05729.7 CBK24142.2 - 0.096 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF4472 PF14739.1 CBK24142.2 - 0.42 11.0 0.2 0.42 11.0 0.2 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) Aminotran_1_2 PF00155.16 CBK24143.2 - 7.7e-77 258.6 0.0 8.7e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4014 PF13198.1 CBK24144.2 - 0.089 13.2 1.4 2.9 8.3 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) NUDIX PF00293.23 CBK24146.2 - 3e-09 36.6 0.1 3.6e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain EMP70 PF02990.11 CBK24147.2 - 1.6e-38 132.5 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Spt20 PF12090.3 CBK24147.2 - 0.094 12.0 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Spt20 family STAT1_TAZ2bind PF12162.3 CBK24148.2 - 0.0019 17.5 0.0 0.87 9.0 0.0 2.8 2 0 0 2 2 2 2 STAT1 TAZ2 binding domain DUF2562 PF10814.3 CBK24148.2 - 2.5 8.0 0.0 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2562) XG_FTase PF03254.8 CBK24149.2 - 1.3e-08 33.8 0.0 0.00046 18.8 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase BRCT PF00533.21 CBK24149.2 - 2e-05 24.6 0.0 0.00043 20.3 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 CBK24149.2 - 0.0017 18.4 0.1 0.0063 16.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.2 CBK24149.2 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain TBPIP_N PF15517.1 CBK24149.2 - 0.017 14.7 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Tetraspannin PF00335.15 CBK24150.2 - 8.4e-21 74.2 17.5 1.1e-20 73.9 12.1 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.10 CBK24150.2 - 5.7e-07 29.5 14.1 1e-06 28.7 9.8 1.4 1 1 0 1 1 1 1 CD20-like family RSN1_TM PF13967.1 CBK24150.2 - 0.0025 17.4 0.6 0.0068 15.9 0.4 1.8 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF1372 PF07116.6 CBK24150.2 - 0.62 10.0 3.6 1 9.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) WSS_VP PF12175.3 CBK24150.2 - 0.75 8.8 5.6 0.17 10.9 0.4 1.9 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP SUR7 PF06687.7 CBK24150.2 - 5.3 6.5 16.0 0.19 11.3 5.5 2.1 2 0 0 2 2 2 0 SUR7/PalI family DUF4231 PF14015.1 CBK24151.2 - 0.8 9.7 3.1 0.47 10.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Tetraspannin PF00335.15 CBK24151.2 - 1.3 8.2 32.9 3.3 6.9 12.3 3.0 1 1 1 2 2 2 0 Tetraspanin family Methyltransf_11 PF08241.7 CBK24152.2 - 2e-05 25.0 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK24152.2 - 0.00021 21.6 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBK24152.2 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBK24152.2 - 0.0059 16.2 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Fer2_3 PF13085.1 CBK24153.2 - 2e-33 114.5 0.0 3.7e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK24153.2 - 1.1e-09 38.4 6.9 1.1e-09 38.4 4.8 2.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK24153.2 - 1.6e-09 37.6 4.9 1.6e-09 37.6 3.4 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK24153.2 - 5.6e-06 26.6 3.1 5.6e-06 26.6 2.2 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CBK24153.2 - 3.1e-05 23.6 0.2 3.1e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 CBK24153.2 - 0.00026 20.7 3.6 0.00026 20.7 2.5 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK24153.2 - 0.00043 20.4 9.1 0.048 13.9 0.2 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK24153.2 - 0.0024 18.2 5.2 0.0024 18.2 3.6 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK24153.2 - 4.4 7.4 17.9 1.5 8.9 2.8 3.8 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_15 PF13459.1 CBK24153.2 - 7.1 7.2 9.0 2.7 8.6 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain 6PGD PF00393.14 CBK24154.2 - 2.6e-45 154.8 0.0 3.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBK24154.2 - 1.2e-18 67.5 0.0 2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP_bind_1 PF03029.12 CBK24155.2 - 1.4e-70 237.5 0.0 1.6e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBK24155.2 - 2.7e-06 28.1 0.1 7.6e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK24155.2 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBK24155.2 - 0.00098 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 CBK24155.2 - 0.0014 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBK24155.2 - 0.0025 17.8 0.0 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 CBK24155.2 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBK24155.2 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBK24155.2 - 0.021 14.6 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBK24155.2 - 0.026 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 CBK24155.2 - 0.052 13.8 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 CBK24155.2 - 0.057 12.3 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 CBK24155.2 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 CBK24155.2 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase DUF258 PF03193.11 CBK24155.2 - 0.084 12.0 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBK24155.2 - 0.085 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK24155.2 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 CBK24155.2 - 0.17 11.4 0.0 0.45 10.0 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA_int_endo PF01974.12 CBK24156.2 - 8e-16 57.6 0.2 1e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.20 CBK24157.2 - 0.0023 17.1 0.0 0.0025 16.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBK24159.2 - 8.2e-53 179.2 0.0 1.3e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24159.2 - 5.4e-27 94.4 0.0 9.6e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PCI PF01399.22 CBK24159.2 - 1.3e-08 35.1 0.1 1e-06 29.0 0.0 3.3 3 0 0 3 3 3 1 PCI domain Kinase-like PF14531.1 CBK24159.2 - 1.6e-07 30.5 0.0 2.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MmgE_PrpD PF03972.9 CBK24159.2 - 0.054 11.6 0.0 0.12 10.5 0.0 1.5 1 0 0 1 1 1 0 MmgE/PrpD family AAA_5 PF07728.9 CBK24160.2 - 4.9e-54 181.8 0.0 5.3e-13 48.8 0.0 7.3 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) PRELI PF04707.9 CBK24160.2 - 5.9e-26 90.9 0.0 1.4e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 PRELI-like family AAA_22 PF13401.1 CBK24160.2 - 3.9e-15 56.1 0.3 0.023 14.8 0.0 6.2 6 2 0 6 6 4 3 AAA domain AAA_14 PF13173.1 CBK24160.2 - 1.7e-13 50.5 0.0 0.0054 16.6 0.0 5.8 4 0 0 4 4 4 3 AAA domain AAA_3 PF07726.6 CBK24160.2 - 2.6e-11 43.2 0.0 5.1e-07 29.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBK24160.2 - 4.7e-06 26.8 0.0 0.21 11.7 0.0 4.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBK24160.2 - 3.2e-05 23.8 0.0 0.17 11.7 0.0 4.6 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CBK24160.2 - 0.00047 20.2 1.7 2.9 7.8 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain AAA_10 PF12846.2 CBK24160.2 - 0.009 15.4 0.0 0.18 11.1 0.0 3.4 4 0 0 4 4 4 1 AAA-like domain AAA_17 PF13207.1 CBK24160.2 - 0.042 14.6 1.4 11 6.8 0.0 5.0 5 1 0 5 5 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK24160.2 - 0.046 13.1 0.0 15 4.9 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CBK24160.2 - 0.056 13.7 0.0 10 6.4 0.0 3.2 2 0 0 2 2 2 0 ABC transporter Virul_Fac PF10139.4 CBK24160.2 - 0.079 10.8 0.1 1.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative bacterial virulence factor AAA_30 PF13604.1 CBK24160.2 - 0.092 12.3 0.0 22 4.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 CBK24160.2 - 0.23 11.0 0.1 20 4.8 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBK24160.2 - 0.49 10.1 0.0 59 3.5 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain KfrA_N PF11740.3 CBK24160.2 - 3.3 8.1 0.2 7.9 6.9 0.1 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RRM_1 PF00076.17 CBK24161.2 - 4.9e-21 74.1 0.1 8.8e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24161.2 - 5.9e-14 51.7 0.0 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24161.2 - 4.1e-10 39.3 0.0 6.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CBK24161.2 - 0.12 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PRP1_N PF06424.7 CBK24163.2 - 0.048 13.9 0.2 14 5.9 0.1 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF822 PF05687.8 CBK24164.2 - 0.22 11.8 2.8 0.36 11.1 2.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) AAA PF00004.24 CBK24165.2 - 6.8e-40 136.3 0.0 1e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBK24165.2 - 1e-06 28.8 0.4 7.1e-05 22.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBK24165.2 - 2.7e-06 26.5 0.0 4.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBK24165.2 - 1.8e-05 24.4 0.3 6.7e-05 22.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBK24165.2 - 3e-05 24.0 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CBK24165.2 - 3.1e-05 23.4 0.8 0.032 13.6 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 CBK24165.2 - 5.6e-05 23.9 0.0 0.00012 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBK24165.2 - 5.8e-05 23.0 0.1 0.00027 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CBK24165.2 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBK24165.2 - 0.00019 20.3 0.0 0.0003 19.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Vps4_C PF09336.5 CBK24165.2 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 CBK24165.2 - 0.00036 19.9 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBK24165.2 - 0.00066 19.7 0.1 0.003 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CBK24165.2 - 0.00081 18.6 0.1 0.0019 17.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CBK24165.2 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CBK24165.2 - 0.001 17.9 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 CBK24165.2 - 0.0013 18.4 0.1 0.14 11.7 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 CBK24165.2 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK24165.2 - 0.0039 16.9 0.4 0.013 15.2 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 CBK24165.2 - 0.0045 16.5 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBK24165.2 - 0.0078 16.3 0.0 0.021 15.0 0.0 1.9 2 1 0 2 2 1 1 RNA helicase AAA_11 PF13086.1 CBK24165.2 - 0.0096 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBK24165.2 - 0.011 14.8 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CBK24165.2 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBK24165.2 - 0.014 14.8 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 CBK24165.2 - 0.016 14.6 0.0 0.068 12.5 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase ResIII PF04851.10 CBK24165.2 - 0.022 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CBK24165.2 - 0.045 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Bac_DnaA PF00308.13 CBK24165.2 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 CBK24165.2 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 CBK24165.2 - 0.11 11.3 0.0 0.72 8.6 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein KaiC PF06745.8 CBK24165.2 - 0.16 11.0 0.5 1.1 8.2 0.1 2.1 1 1 1 2 2 2 0 KaiC Phycoerythr_ab PF02972.9 CBK24166.2 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain DUF1375 PF07119.7 CBK24167.2 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1375) WD40 PF00400.27 CBK24168.2 - 3.4e-10 39.4 18.7 1.2e-05 25.0 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Sec16_C PF12931.2 CBK24168.2 - 7.1e-08 32.5 0.1 1.4e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DUF3312 PF11768.3 CBK24168.2 - 0.0058 14.9 0.1 0.0091 14.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 CBK24168.2 - 0.012 15.0 1.0 68 3.0 0.0 5.0 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF512 PF04459.7 CBK24168.2 - 0.2 10.7 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Methyltransf_26 PF13659.1 CBK24169.2 - 3.6e-11 43.1 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK24169.2 - 1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBK24169.2 - 0.0035 16.9 0.0 0.0037 16.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBK24169.2 - 0.0053 15.8 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 CBK24169.2 - 0.017 15.4 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CBK24169.2 - 0.067 12.2 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L3 PF00297.17 CBK24170.2 - 5.2e-40 137.4 3.6 1.9e-38 132.3 2.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 KOW PF00467.24 CBK24170.2 - 0.46 10.2 3.6 3 7.7 0.1 3.5 3 0 0 3 3 3 0 KOW motif DEAD PF00270.24 CBK24172.2 - 3.2e-38 130.8 0.3 5e-38 130.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24172.2 - 2.3e-19 69.0 0.3 6.6e-12 45.1 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBK24172.2 - 2.2e-08 34.1 0.0 2.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Astro_capsid PF03115.9 CBK24172.2 - 0.12 10.6 2.0 0.18 10.0 1.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CBK24172.2 - 0.5 8.2 13.7 0.89 7.4 9.5 1.3 1 0 0 1 1 1 0 Nop14-like family SAP PF02037.22 CBK24173.2 - 4.7e-07 29.1 0.0 7.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SAP domain DUF4407 PF14362.1 CBK24173.2 - 2.5 6.9 8.4 1.4 7.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) fn3 PF00041.16 CBK24174.2 - 3.2e-10 39.9 0.1 0.0001 22.3 0.0 4.8 5 0 0 5 5 5 3 Fibronectin type III domain Big_5 PF13205.1 CBK24174.2 - 8.5e-07 29.5 3.1 0.039 14.5 0.0 5.1 4 1 1 5 5 5 2 Bacterial Ig-like domain GETHR PF05671.6 CBK24174.2 - 0.00012 21.1 6.0 0.024 13.7 1.0 3.1 1 1 1 2 2 2 2 GETHR pentapeptide repeat (5 copies) Aa_trans PF01490.13 CBK24175.2 - 9e-58 195.6 30.1 1.1e-57 195.3 20.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PT PF04886.7 CBK24175.2 - 0.29 10.4 6.2 0.63 9.4 4.3 1.5 1 0 0 1 1 1 0 PT repeat AAA PF00004.24 CBK24177.2 - 1.1e-08 35.4 0.0 2.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Choline_kinase PF01633.15 CBK24178.2 - 2.7e-19 69.6 0.6 2.7e-19 69.6 0.4 1.9 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CBK24178.2 - 3.5e-08 33.4 0.1 3.5e-08 33.4 0.1 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBK24178.2 - 0.0098 15.0 0.2 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pro_isomerase PF00160.16 CBK24179.2 - 4.1e-44 150.5 0.0 4.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CCT PF06203.9 CBK24180.2 - 0.0014 18.1 0.1 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 CCT motif PsbM PF05151.7 CBK24180.2 - 0.55 9.8 3.9 2 8.0 0.8 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) Synaptobrevin PF00957.16 CBK24181.2 - 4e-27 93.6 2.5 6.6e-27 92.9 1.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBK24181.2 - 5.4e-15 54.7 0.6 9.7e-15 53.8 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Rifin_STEVOR PF02009.11 CBK24181.2 - 1.6 8.3 5.9 2.4 7.7 3.8 1.4 1 1 0 1 1 1 0 Rifin/stevor family Sigma_reg_N PF13800.1 CBK24181.2 - 2.1 8.4 4.8 43 4.2 2.3 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal NAD_synthase PF02540.12 CBK24182.2 - 1.2e-31 109.4 0.0 2.4e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 CBK24182.2 - 0.067 11.7 0.1 0.094 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBK24182.2 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MORN_2 PF07661.8 CBK24184.2 - 0.00067 19.3 12.5 0.39 10.8 0.3 4.9 4 0 0 4 4 4 2 MORN repeat variant Laminin_G_3 PF13385.1 CBK24184.2 - 4.9 7.3 8.1 6.3 7.0 1.6 2.5 2 1 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Aminotran_5 PF00266.14 CBK24185.2 - 3.7e-89 299.0 0.0 4.9e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBK24185.2 - 1.2e-10 40.9 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK24185.2 - 3.4e-10 39.5 0.0 4.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBK24185.2 - 6.7e-08 31.9 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CBK24185.2 - 0.0005 18.6 0.1 0.00067 18.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NIPSNAP PF07978.8 CBK24185.2 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NIPSNAP Es2 PF09751.4 CBK24186.2 - 1e-42 147.0 8.5 5.4e-41 141.3 5.9 2.2 1 1 0 1 1 1 1 Nuclear protein Es2 Actin PF00022.14 CBK24188.2 - 1.3e-141 471.5 0.0 1.5e-141 471.3 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBK24188.2 - 0.012 15.9 0.1 0.047 14.0 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M18 PF02127.10 CBK24189.2 - 1.9e-142 474.7 0.0 2.2e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBK24189.2 - 1.9e-08 33.4 0.7 3.8e-05 22.6 0.1 2.9 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 CBK24189.2 - 4.2e-05 23.1 0.0 8.7e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Ribosomal_S9 PF00380.14 CBK24190.2 - 8.5e-39 132.5 0.9 1.2e-38 132.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Big_5 PF13205.1 CBK24191.2 - 1.3e-06 28.9 0.7 0.012 16.2 0.0 3.2 2 1 1 3 3 3 2 Bacterial Ig-like domain fn3 PF00041.16 CBK24192.2 - 4.9e-07 29.7 0.0 3.6 7.7 0.0 5.0 5 0 0 5 5 5 3 Fibronectin type III domain SAP PF02037.22 CBK24193.2 - 3e-07 29.7 0.0 3.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 SAP domain Trypan_PARP PF05887.6 CBK24194.2 - 0.0041 16.9 7.6 0.0059 16.4 5.3 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) hSac2 PF12456.3 CBK24194.2 - 0.13 11.6 1.2 5.9 6.3 0.0 3.0 1 1 2 3 3 3 0 Inositol phosphatase DUF2360 PF10152.4 CBK24194.2 - 0.22 11.7 1.3 0.33 11.2 0.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Neisseria_TspB PF05616.8 CBK24194.2 - 3.2 6.0 10.4 4.5 5.5 7.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Fer2_3 PF13085.1 CBK24195.2 - 9.4e-33 112.3 0.1 1.7e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBK24195.2 - 1.1e-09 38.4 6.9 1.1e-09 38.4 4.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK24195.2 - 1.5e-09 37.7 4.9 1.5e-09 37.7 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK24195.2 - 4.2e-06 27.0 2.8 4.2e-06 27.0 1.9 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK24195.2 - 0.00025 20.7 3.6 0.00025 20.7 2.5 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CBK24195.2 - 0.00034 20.2 0.4 0.00034 20.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CBK24195.2 - 0.00081 19.6 10.6 0.054 13.7 0.2 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK24195.2 - 0.0023 18.2 5.2 0.0023 18.2 3.6 2.9 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK24195.2 - 1.7 8.7 16.3 1.4 8.9 2.8 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.1 CBK24195.2 - 5.3 7.6 9.1 2.6 8.6 0.2 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain CBF PF03914.12 CBK24196.2 - 8.9e-20 70.7 3.2 8.9e-20 70.7 0.4 2.3 3 0 0 3 3 3 1 CBF/Mak21 family Elongin_A PF06881.6 CBK24196.2 - 0.36 11.2 3.0 1.2 9.5 1.7 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3134 PF11332.3 CBK24196.2 - 1.7 8.7 6.0 3.8 7.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) XRN_N PF03159.13 CBK24197.2 - 2.2e-94 315.2 1.4 7.1e-94 313.6 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PI3_PI4_kinase PF00454.22 CBK24197.2 - 5.6e-20 71.8 0.1 4e-19 69.0 0.0 2.4 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase zf-CCHC PF00098.18 CBK24197.2 - 0.048 13.6 0.6 0.13 12.2 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Attacin_C PF03769.10 CBK24197.2 - 0.095 12.8 1.2 0.53 10.4 0.3 2.1 2 0 0 2 2 2 0 Attacin, C-terminal region zf-CCHC_3 PF13917.1 CBK24197.2 - 0.12 12.1 0.6 0.26 11.0 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle ENTH PF01417.15 CBK24198.2 - 2.4e-31 108.1 0.1 4.2e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CBK24198.2 - 0.0045 15.7 0.0 0.0092 14.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain Nop14 PF04147.7 CBK24198.2 - 0.58 8.0 27.5 0.74 7.6 19.0 1.3 1 0 0 1 1 1 0 Nop14-like family RNase_PH PF01138.16 CBK24200.2 - 5.6e-26 91.4 0.0 1.3e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Mre11_DNA_bind PF04152.9 CBK24200.2 - 7e-19 68.3 0.0 7.8e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CBK24200.2 - 9.8e-16 57.7 0.6 2.2e-15 56.6 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK24200.2 - 0.0016 18.2 0.0 0.0042 16.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 CBK24202.2 - 1.9e-38 132.1 0.0 2.3e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24202.2 - 5.6e-21 74.7 0.0 5.8e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24202.2 - 5.4e-06 25.5 0.0 6e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK24202.2 - 0.091 11.8 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK24202.2 - 0.1 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Big_5 PF13205.1 CBK24203.2 - 8.8e-19 68.0 7.7 2.9e-09 37.4 0.0 6.2 7 0 0 7 7 7 3 Bacterial Ig-like domain fn3 PF00041.16 CBK24203.2 - 7e-09 35.6 2.2 0.02 15.0 0.0 5.8 5 0 0 5 5 5 1 Fibronectin type III domain CopC PF04234.7 CBK24203.2 - 3.5e-05 24.3 0.8 0.61 10.7 0.0 4.1 3 1 1 4 4 4 2 CopC domain MMR_HSR1 PF01926.18 CBK24204.2 - 9.4e-43 144.8 0.0 4.3e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 CBK24204.2 - 2.2e-28 98.0 0.1 7.2e-28 96.3 0.0 1.9 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 CBK24204.2 - 6.6e-21 74.2 0.0 1.8e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.11 CBK24204.2 - 3.9e-14 52.2 0.0 1.9e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 CBK24204.2 - 5.5e-13 49.0 0.6 0.0099 15.7 0.0 4.4 3 1 1 4 4 4 3 Dynamin family GTP_EFTU PF00009.22 CBK24204.2 - 4.7e-09 35.9 0.9 6.9e-05 22.3 0.1 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBK24204.2 - 6.4e-09 35.1 0.3 0.001 18.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBK24204.2 - 2.5e-07 31.0 0.1 0.027 14.7 0.0 2.6 2 1 0 2 2 2 2 ABC transporter Miro PF08477.8 CBK24204.2 - 1.3e-06 28.9 0.0 0.012 16.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein SRPRB PF09439.5 CBK24204.2 - 1.7e-05 24.1 0.1 0.075 12.2 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CBK24204.2 - 0.00048 19.5 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arf PF00025.16 CBK24204.2 - 0.00059 19.1 0.4 0.11 11.7 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family Septin PF00735.13 CBK24204.2 - 0.00069 18.7 1.2 0.86 8.5 0.0 3.2 2 1 1 3 3 3 2 Septin G-alpha PF00503.15 CBK24204.2 - 0.00069 18.4 0.3 1 7.9 0.1 3.3 4 0 0 4 4 4 1 G-protein alpha subunit AAA_14 PF13173.1 CBK24204.2 - 0.0015 18.4 0.1 0.31 10.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 CBK24204.2 - 0.0016 18.1 0.5 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBK24204.2 - 0.0021 18.3 0.2 2.9 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBK24204.2 - 0.0027 17.6 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 CBK24204.2 - 0.0029 17.0 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Ras family cobW PF02492.14 CBK24204.2 - 0.0038 16.7 0.7 1.8 7.9 0.1 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CBK24204.2 - 0.0057 16.3 0.1 3.6 7.2 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CBK24204.2 - 0.0063 16.0 0.1 0.3 10.5 0.0 2.8 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_10 PF12846.2 CBK24204.2 - 0.0064 15.9 0.1 0.88 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CBK24204.2 - 0.015 15.3 0.1 8.2 6.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 CBK24204.2 - 0.032 13.3 0.0 0.11 11.5 0.0 1.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 CBK24204.2 - 0.033 15.0 0.0 9.4 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain GBP PF02263.14 CBK24204.2 - 0.057 12.4 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain NB-ARC PF00931.17 CBK24204.2 - 0.059 12.2 0.0 4.7 5.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_21 PF13304.1 CBK24204.2 - 0.09 12.7 0.3 8.6 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PCP_red PF08369.5 CBK24205.2 - 0.088 12.6 1.1 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Big_5 PF13205.1 CBK24206.2 - 1.3e-25 90.0 0.9 7e-10 39.4 0.0 3.1 3 0 0 3 3 3 3 Bacterial Ig-like domain CopC PF04234.7 CBK24206.2 - 0.017 15.7 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 0 CopC domain SPX PF03105.14 CBK24207.2 - 0.0094 15.7 4.3 0.011 15.5 3.0 1.1 1 0 0 1 1 1 1 SPX domain DUF4611 PF15387.1 CBK24207.2 - 0.034 14.3 2.3 0.048 13.8 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) GSIII_N PF12437.3 CBK24208.2 - 2.5e-61 205.8 0.0 6e-61 204.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 CBK24208.2 - 1.3e-37 129.3 0.0 2.1e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain LAGLIDADG_3 PF14528.1 CBK24208.2 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 LAGLIDADG-like domain La PF05383.12 CBK24209.2 - 1.1e-20 73.2 0.1 2.3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBK24209.2 - 6.5e-19 67.6 0.1 9.3e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK24209.2 - 7.4e-14 51.1 0.4 1.3e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK24209.2 - 2.2e-12 46.7 5.0 5.2e-10 39.1 1.2 2.5 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.1 CBK24209.2 - 1.7e-09 37.3 0.5 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.11 CBK24209.2 - 0.017 14.4 0.0 0.034 13.4 0.0 1.5 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Lactamase_B_2 PF12706.2 CBK24210.2 - 8.4e-22 77.6 0.0 4.2e-20 72.1 0.0 2.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK24210.2 - 1.3e-06 28.2 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 CBK24210.2 - 0.13 11.2 0.1 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Thioredoxin PF00085.15 CBK24211.2 - 9.4e-11 41.3 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 CBK24211.2 - 0.0013 18.2 1.1 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 CBK24211.2 - 0.0023 18.0 0.1 0.0042 17.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CBK24211.2 - 0.0061 16.5 2.7 0.016 15.1 1.9 1.8 1 1 0 1 1 1 1 Thioredoxin DUF393 PF04134.7 CBK24211.2 - 0.012 16.7 0.1 0.022 15.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF393 HyaE PF07449.6 CBK24211.2 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 CBK24211.2 - 0.13 12.3 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Acetyltransf_7 PF13508.1 CBK24212.2 - 1e-06 28.7 0.1 1.4e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBK24212.2 - 0.0026 17.7 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NodZ PF05830.6 CBK24213.2 - 2.9e-10 39.2 0.0 4.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.4 CBK24213.2 - 0.00096 18.3 0.2 0.0027 16.8 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.8 CBK24213.2 - 0.0094 14.4 0.4 0.041 12.3 0.0 1.9 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Phospholip_B PF04916.8 CBK24213.2 - 0.091 10.8 0.1 0.14 10.2 0.1 1.2 1 0 0 1 1 1 0 Phospholipase B Glyco_hydro_47 PF01532.15 CBK24214.2 - 1e-144 482.6 0.5 1.2e-144 482.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA_12 PF13087.1 CBK24215.2 - 1.4e-61 207.3 0.0 2.8e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK24215.2 - 2.2e-50 171.4 0.2 4.9e-50 170.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 CBK24215.2 - 2e-32 111.8 10.2 8.6e-32 109.8 4.6 3.0 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_19 PF13245.1 CBK24215.2 - 8.2e-14 51.1 0.4 3.3e-13 49.1 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBK24215.2 - 1.8e-10 40.7 0.0 2.6e-09 36.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBK24215.2 - 6.1e-06 25.4 0.0 3e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CBK24215.2 - 1.6e-05 24.5 0.0 0.28 10.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CBK24215.2 - 3e-05 23.9 0.1 0.0001 22.1 0.0 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK24215.2 - 0.0001 21.8 0.0 0.00029 20.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 CBK24215.2 - 0.00012 21.2 0.0 0.036 13.0 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 CBK24215.2 - 0.00089 18.6 0.0 0.072 12.3 0.0 2.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain KaiC PF06745.8 CBK24215.2 - 0.0046 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC PhoH PF02562.11 CBK24215.2 - 0.0046 16.2 0.1 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 CBK24215.2 - 0.0052 16.4 0.0 0.0052 16.4 0.0 1.8 2 0 0 2 2 1 1 Helicase Sigma54_activat PF00158.21 CBK24215.2 - 0.0068 15.8 0.0 0.48 9.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 CBK24215.2 - 0.011 15.7 0.0 0.26 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_25 PF13481.1 CBK24215.2 - 0.018 14.4 0.0 0.051 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBK24215.2 - 0.024 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CBK24215.2 - 0.044 14.0 0.1 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBK24215.2 - 0.071 13.2 0.0 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CBK24215.2 - 0.088 12.2 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.1 CBK24215.2 - 0.11 12.6 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain SMC_N PF02463.14 CBK24215.2 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DnaB_C PF03796.10 CBK24215.2 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA PF00004.24 CBK24215.2 - 0.14 12.3 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Syja_N PF02383.13 CBK24216.2 - 2.2e-07 29.9 0.0 4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.13 CBK24217.2 - 9.6e-53 178.9 0.0 1.3e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain zf-ribbon_3 PF13248.1 CBK24217.2 - 0.11 11.7 4.5 0.25 10.6 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain RIC1 PF07064.8 CBK24218.2 - 7.5e-11 41.9 6.8 3e-10 40.0 4.7 2.1 1 1 0 1 1 1 1 RIC1 Ras PF00071.17 CBK24219.2 - 1.1e-57 194.0 1.5 1.5e-57 193.4 1.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK24219.2 - 3.5e-18 66.2 0.1 6.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK24219.2 - 5.2e-14 51.8 0.1 7.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK24219.2 - 5.2e-06 26.0 0.3 1.1e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBK24219.2 - 5.6e-05 22.4 0.2 8.4e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBK24219.2 - 0.00015 21.8 0.1 0.00046 20.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CBK24219.2 - 0.001 18.2 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain VirE PF05272.6 CBK24219.2 - 0.004 16.6 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E SRPRB PF09439.5 CBK24219.2 - 0.0055 15.9 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBK24219.2 - 0.017 15.0 0.3 0.03 14.2 0.2 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK24219.2 - 0.037 13.3 0.2 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Pho88 PF10032.4 CBK24219.2 - 0.079 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphate transport (Pho88) Sp38 PF07354.7 CBK24219.2 - 0.16 10.6 0.0 0.16 10.6 0.0 2.1 3 0 0 3 3 3 0 Zona-pellucida-binding protein (Sp38) Proteasome PF00227.21 CBK24220.2 - 4.5e-30 104.3 0.0 5.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Calsequestrin PF01216.12 CBK24220.2 - 0.012 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin ATP-grasp_2 PF08442.5 CBK24221.2 - 1e-67 227.4 0.0 1.6e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBK24221.2 - 6.4e-24 84.3 1.3 9.9e-24 83.6 0.9 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBK24221.2 - 0.021 14.4 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain E2F_TDP PF02319.15 CBK24222.2 - 2.3e-06 27.0 0.2 5.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PspA_IM30 PF04012.7 CBK24222.2 - 5.5e-05 22.6 0.4 7.9e-05 22.1 0.3 1.1 1 0 0 1 1 1 1 PspA/IM30 family Uds1 PF15456.1 CBK24222.2 - 0.0084 16.0 0.4 0.014 15.4 0.3 1.3 1 0 0 1 1 1 1 Up-regulated During Septation Pox_A_type_inc PF04508.7 CBK24222.2 - 0.66 9.9 5.0 1.5 8.7 3.4 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ras PF00071.17 CBK24223.2 - 1.3e-42 144.9 0.4 1.6e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK24223.2 - 4.4e-16 59.4 0.0 6.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK24223.2 - 3.9e-12 45.7 0.0 5.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBK24223.2 - 2.7e-07 29.9 0.1 3.4e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBK24223.2 - 4.1e-05 23.5 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK24223.2 - 0.00046 19.6 0.2 0.0024 17.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBK24223.2 - 0.0019 16.9 0.0 0.09 11.4 0.0 2.2 2 1 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.13 CBK24223.2 - 0.0037 16.5 0.2 0.029 13.6 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF815 PF05673.8 CBK24223.2 - 0.038 12.9 0.0 0.082 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBK24223.2 - 0.039 13.8 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain She9_MDM33 PF05546.6 CBK24224.2 - 8.5e-15 54.8 13.2 9.4e-15 54.7 9.1 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Exonuc_VII_L PF02601.10 CBK24224.2 - 0.13 11.4 6.3 0.15 11.2 4.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.3 CBK24224.2 - 0.66 9.7 9.9 1.2 8.9 6.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IcmL PF11393.3 CBK24224.2 - 2.4 8.1 6.0 2.4 8.1 0.1 2.9 1 1 1 3 3 3 0 Macrophage killing protein with similarity to conjugation protein Phage_Gp23 PF10669.4 CBK24224.2 - 6.4 6.9 7.7 0.41 10.7 1.1 2.0 1 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) PH PF00169.24 CBK24225.2 - 4.2e-07 30.1 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 PH domain zf-RING_2 PF13639.1 CBK24226.2 - 4.9e-13 48.6 1.7 6.9e-13 48.2 1.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK24226.2 - 1.2e-07 31.6 1.4 1.8e-07 31.1 0.8 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBK24226.2 - 2.1e-07 30.8 3.1 3.3e-07 30.1 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK24226.2 - 3.5e-07 29.7 1.8 5.8e-07 29.0 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK24226.2 - 8.1e-06 25.4 2.0 1.2e-05 24.9 1.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBK24226.2 - 2.5e-05 23.9 1.2 2.5e-05 23.9 0.8 1.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CBK24226.2 - 0.00011 21.7 2.1 0.00016 21.3 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBK24226.2 - 0.0015 18.3 1.8 0.0074 16.0 1.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 CBK24226.2 - 0.0019 18.3 2.1 0.0027 17.8 1.5 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.3 CBK24226.2 - 0.0022 17.8 1.7 0.0047 16.8 1.2 1.5 1 1 0 1 1 1 1 FANCL C-terminal domain DUF2175 PF09943.4 CBK24226.2 - 0.023 14.7 0.8 0.083 12.9 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) SUD-M PF11633.3 CBK24226.2 - 0.03 13.5 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain DUF3918 PF13056.1 CBK24226.2 - 0.037 13.3 1.0 0.051 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) zf-C3HC4_4 PF15227.1 CBK24226.2 - 0.042 13.7 4.2 0.39 10.6 3.0 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 CBK24226.2 - 0.069 12.8 0.9 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 CBK24226.2 - 0.076 12.7 1.5 0.12 12.0 1.1 1.3 1 0 0 1 1 1 0 PHD-finger Ribosomal_S3Ae PF01015.13 CBK24227.2 - 2e-74 249.1 4.0 2.6e-74 248.7 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.17 CBK24227.2 - 0.0027 17.4 0.1 0.0027 17.4 0.1 2.0 3 0 0 3 3 3 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.11 CBK24227.2 - 0.042 13.2 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Collagen PF01391.13 CBK24228.2 - 0.27 10.8 6.5 0.33 10.5 3.4 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) PRKCSH PF07915.8 CBK24230.2 - 1.5e-06 28.9 1.6 3.6e-06 27.6 1.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.9 CBK24230.2 - 7.1e-05 22.7 0.1 0.00021 21.2 0.1 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRKCSH_1 PF13015.1 CBK24230.2 - 0.00053 19.4 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF2757 PF10955.3 CBK24230.2 - 0.0074 16.4 0.2 4.8 7.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2757) zf-LITAF-like PF10601.4 CBK24230.2 - 0.13 12.1 6.0 0.15 11.9 0.6 2.7 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain CMS1 PF14617.1 CBK24231.2 - 1e-22 80.4 0.4 1e-22 80.4 0.3 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 CBK24231.2 - 0.0018 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CRAL_TRIO PF00650.15 CBK24231.2 - 0.024 14.1 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Cas_Csy4 PF09618.5 CBK24231.2 - 0.095 12.5 1.5 0.19 11.5 1.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) BRCT PF00533.21 CBK24232.2 - 2.8e-11 43.3 0.0 6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TcdB_N PF12918.2 CBK24232.2 - 6.4 6.9 7.2 4 7.5 0.8 2.4 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DNA_ligase_A_M PF01068.16 CBK24233.2 - 5e-63 212.1 0.2 8.1e-63 211.4 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CBK24233.2 - 1.6e-46 158.3 0.0 3.1e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CBK24233.2 - 1.8e-20 73.1 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CBK24233.2 - 0.036 13.7 0.9 8 6.2 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Peptidase_A21 PF03566.8 CBK24234.2 - 2 6.4 4.5 2.4 6.1 3.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 He_PIG PF05345.7 CBK24235.2 - 2.6e-06 27.3 6.8 1e-05 25.4 4.7 2.1 1 0 0 1 1 1 1 Putative Ig domain Shisa PF13908.1 CBK24235.2 - 3.2e-06 27.4 3.3 5.8e-06 26.5 2.3 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 CBK24235.2 - 0.00026 20.7 2.0 0.00047 19.9 1.4 1.3 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 CBK24235.2 - 0.0007 19.3 2.8 0.0012 18.6 2.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 CBK24235.2 - 0.0029 17.6 0.8 0.0054 16.7 0.6 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OAD_gamma PF04277.8 CBK24235.2 - 0.0091 16.3 0.2 0.04 14.2 0.2 2.0 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain Neur_chan_memb PF02932.11 CBK24235.2 - 0.03 14.2 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region F5_F8_type_C PF00754.20 CBK24235.2 - 0.036 13.9 0.1 0.036 13.9 0.1 2.6 3 0 0 3 3 2 0 F5/8 type C domain EphA2_TM PF14575.1 CBK24235.2 - 0.047 14.0 3.9 0.15 12.4 2.7 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tenui_PVC2 PF06656.6 CBK24235.2 - 0.07 10.9 1.7 0.1 10.3 1.2 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein DUF1510 PF07423.6 CBK24235.2 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4446 PF14584.1 CBK24235.2 - 0.1 12.4 0.9 0.33 10.7 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) ODV-E18 PF10717.4 CBK24235.2 - 0.11 11.9 1.5 0.29 10.6 1.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 CBK24235.2 - 0.23 10.8 5.9 0.45 9.9 4.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Peptidase_S49_N PF08496.5 CBK24235.2 - 0.33 10.7 2.4 0.52 10.0 1.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SP_C-Propep PF08999.5 CBK24235.2 - 0.36 10.3 4.7 0.76 9.3 3.2 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide RAMP PF04901.8 CBK24235.2 - 1.1 9.0 4.6 2 8.1 3.2 1.4 1 0 0 1 1 1 0 Receptor activity modifying family ASFV_J13L PF05568.6 CBK24235.2 - 1.2 8.6 7.8 0.24 10.9 2.5 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein P12 PF12669.2 CBK24235.2 - 1.2 9.3 5.0 2.5 8.3 3.5 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1180 PF06679.7 CBK24235.2 - 1.7 8.5 14.0 0.031 14.1 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CarboxypepD_reg PF13620.1 CBK24236.2 - 1.7e-27 95.2 1.9 4.2e-07 29.9 0.0 6.2 7 0 0 7 7 7 5 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 CBK24236.2 - 4.8e-10 39.3 0.0 0.33 10.7 0.0 5.5 4 2 0 5 5 5 3 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 CBK24237.2 - 4.8e-22 77.8 1.3 1.6e-05 24.8 0.0 4.3 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 CBK24237.2 - 5.2e-11 42.1 0.0 0.00011 21.8 0.0 4.2 4 0 0 4 4 4 3 Cna protein B-type domain DUF4480 PF13715.1 CBK24237.2 - 2.3e-08 33.9 0.1 0.0027 17.7 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4480) UDP-g_GGTase PF06427.6 CBK24237.2 - 0.0005 19.4 0.0 0.00086 18.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase fn3_3 PF14686.1 CBK24237.2 - 0.0059 16.7 0.0 0.52 10.4 0.0 3.0 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II MG1 PF11974.3 CBK24237.2 - 0.092 13.3 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 Alpha-2-macroglobulin MG1 domain Imm38 PF15599.1 CBK24238.2 - 0.07 12.6 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 38 Tetraspannin PF00335.15 CBK24239.2 - 4e-09 36.0 25.2 1.4e-08 34.2 11.4 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF2975 PF11188.3 CBK24239.2 - 3.2 7.4 10.5 12 5.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Fibrinogen_BP PF08017.6 CBK24240.2 - 2.2e-17 62.3 164.2 1.8e-12 46.1 49.5 3.3 2 1 2 4 4 4 3 Fibrinogen binding protein Peptidase_C1 PF00112.18 CBK24241.2 - 6.3e-91 304.1 15.0 1.4e-48 165.6 1.4 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Pox_I6 PF04595.8 CBK24241.2 - 0.015 14.0 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family Peptidase_C1_2 PF03051.10 CBK24241.2 - 0.023 13.2 0.1 0.023 13.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family AAA PF00004.24 CBK24242.2 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NAC PF01849.13 CBK24244.2 - 2.1e-11 43.1 0.0 3.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 NAC domain GSH_synth_ATP PF03917.12 CBK24245.2 - 4.3e-76 255.9 0.0 6.6e-76 255.2 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBK24245.2 - 1.1e-25 89.7 0.1 3e-25 88.3 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic glutathione synthase Sybindin PF04099.7 CBK24246.2 - 2.3e-11 43.5 0.0 2.4e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBK24246.2 - 0.11 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Dynamin_N PF00350.18 CBK24247.2 - 3.4e-09 36.7 0.0 1.4e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBK24247.2 - 9.3e-06 25.5 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK24247.2 - 0.0019 17.6 0.3 0.011 15.1 0.1 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBK24247.2 - 0.0068 16.8 0.1 0.035 14.6 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MFS_1 PF07690.11 CBK24247.2 - 0.02 13.6 0.3 0.032 12.9 0.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily AIG1 PF04548.11 CBK24247.2 - 0.06 12.4 0.2 9.2 5.3 0.0 2.5 2 1 0 2 2 2 0 AIG1 family Nop PF01798.13 CBK24248.2 - 1.3e-59 199.8 0.1 3.1e-59 198.5 0.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBK24248.2 - 1.7e-26 91.8 0.1 3.9e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBK24248.2 - 4.7e-23 81.1 1.3 4.7e-23 81.1 0.9 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 CBK24248.2 - 0.0059 16.6 14.2 0.0087 16.0 9.9 1.2 1 0 0 1 1 1 1 GAGA binding protein-like family RNA_polI_A34 PF08208.6 CBK24248.2 - 0.32 10.6 45.9 0.52 9.9 31.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YqfQ PF14181.1 CBK24248.2 - 1.1 9.3 30.8 2 8.3 21.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein DDHD PF02862.12 CBK24248.2 - 2 8.1 14.1 4.8 6.9 9.5 1.9 2 0 0 2 2 2 0 DDHD domain RR_TM4-6 PF06459.7 CBK24248.2 - 2.5 7.9 27.9 4.1 7.2 19.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.1 CBK24248.2 - 2.9 7.3 10.6 5.5 6.5 7.4 1.5 1 0 0 1 1 1 0 AAA domain Med19 PF10278.4 CBK24248.2 - 3.1 7.4 28.5 8.3 6.0 19.8 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Cation_efflux PF01545.16 CBK24249.2 - 4.6e-69 232.6 4.7 6e-69 232.2 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1510 PF07423.6 CBK24249.2 - 2.1e-05 24.0 1.2 4.5e-05 22.9 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Zip PF02535.17 CBK24249.2 - 0.00023 20.2 25.4 0.00032 19.8 16.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF647 PF04884.9 CBK24249.2 - 0.0031 16.7 0.1 0.0072 15.5 0.1 1.5 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HGTP_anticodon2 PF12745.2 CBK24249.2 - 0.068 12.3 3.1 0.12 11.5 2.2 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Peptidase_M50 PF02163.17 CBK24249.2 - 0.6 9.0 2.6 0.64 8.9 0.0 2.3 2 1 0 2 2 2 0 Peptidase family M50 MatE PF01554.13 CBK24249.2 - 1.1 8.8 9.2 0.82 9.2 0.0 2.9 2 1 1 3 3 3 0 MatE Anoctamin PF04547.7 CBK24249.2 - 1.5 7.4 5.5 0.62 8.6 0.1 2.4 2 1 0 2 2 2 0 Calcium-activated chloride channel FAM176 PF14851.1 CBK24249.2 - 1.6 8.4 5.8 1 9.0 0.0 2.6 1 1 1 2 2 2 0 FAM176 family DUF202 PF02656.10 CBK24249.2 - 2.1 8.6 3.8 15 5.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) BUD22 PF09073.5 CBK24249.2 - 8.1 5.3 14.0 12 4.7 9.7 1.2 1 0 0 1 1 1 0 BUD22 DBR1 PF05011.8 CBK24250.2 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CBK24250.2 - 7.2e-07 28.7 0.6 1.5e-06 27.7 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Yip1 PF04893.12 CBK24251.2 - 1.3e-07 31.2 15.6 2.3e-07 30.5 10.3 1.7 1 1 1 2 2 2 1 Yip1 domain ABC2_membrane_3 PF12698.2 CBK24251.2 - 0.2 10.6 15.6 0.25 10.3 10.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-H2C2_2 PF13465.1 CBK24252.2 - 2.4e-08 33.8 5.4 2.4e-08 33.8 3.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CBK24252.2 - 5.6e-05 23.2 17.2 0.0021 18.2 1.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK24252.2 - 7.7e-05 22.7 15.4 0.0033 17.6 1.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBK24252.2 - 0.00095 19.2 2.2 0.00095 19.2 1.5 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF3505 PF12013.3 CBK24252.2 - 0.014 15.6 3.0 2.3 8.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) MENTAL PF10457.4 CBK24252.2 - 0.023 14.3 0.0 0.028 14.0 0.0 1.3 1 1 0 1 1 1 0 Cholesterol-capturing domain MMR_HSR1 PF01926.18 CBK24253.2 - 1.7e-08 34.4 0.2 1e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK24253.2 - 3.6e-05 23.2 0.0 6.4e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CBK24253.2 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.13 CBK24253.2 - 0.017 14.4 0.2 0.051 12.8 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2331 PF10093.4 CBK24253.2 - 0.13 10.9 0.0 0.24 10.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) CDC73 PF05179.9 CBK24254.2 - 8e-05 22.1 0.0 9.6e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Ribosomal_L32e PF01655.13 CBK24255.2 - 6.2e-46 154.9 0.3 7.8e-46 154.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Nucleotid_trans PF03407.11 CBK24256.2 - 3.3e-19 69.5 0.1 5.2e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Coatomer_WDAD PF04053.9 CBK24257.2 - 7.5e-94 315.0 0.0 1.3e-93 314.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CBK24257.2 - 1e-44 148.8 0.9 1.1e-11 44.1 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK24257.2 - 0.00011 20.5 0.0 0.044 11.9 0.0 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TPR_2 PF07719.12 CBK24257.2 - 0.083 12.8 2.8 0.26 11.3 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_2 PF13646.1 CBK24258.2 - 1.9e-34 117.8 37.6 8.7e-06 25.9 0.0 15.3 5 3 10 15 15 15 11 HEAT repeats HEAT PF02985.17 CBK24258.2 - 2.2e-34 114.4 25.7 0.039 14.0 0.0 21.4 24 0 0 24 24 23 7 HEAT repeat HEAT_EZ PF13513.1 CBK24258.2 - 3.3e-17 62.4 36.1 0.31 11.5 0.1 16.7 16 3 2 18 18 18 4 HEAT-like repeat CLASP_N PF12348.3 CBK24258.2 - 3.6e-15 55.9 11.7 0.015 14.6 0.1 9.0 6 4 4 10 10 10 5 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBK24258.2 - 2.5e-14 53.4 11.5 0.2 12.0 0.1 11.3 11 3 4 16 16 14 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBK24258.2 - 2.5e-09 37.2 15.4 0.00091 19.1 0.0 9.5 9 3 1 11 11 11 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBK24258.2 - 2.7e-09 35.9 22.7 0.0038 15.6 0.0 8.3 3 2 2 7 7 7 4 Adaptin N terminal region ParcG PF10274.4 CBK24258.2 - 4.9e-08 33.0 3.1 0.62 9.9 0.0 7.2 8 1 1 9 9 8 1 Parkin co-regulated protein Cohesin_HEAT PF12765.2 CBK24258.2 - 0.00066 19.5 3.8 2.8 7.9 0.1 6.0 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 CBK24258.2 - 0.0011 18.7 20.6 36 4.3 0.0 10.4 11 0 0 11 11 11 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 CBK24258.2 - 0.011 15.6 2.8 0.22 11.4 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) DUF3437 PF11919.3 CBK24258.2 - 0.053 13.2 0.4 11 5.7 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) DUF2669 PF10876.3 CBK24258.2 - 0.092 12.4 0.0 7.3 6.2 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2669) RNA_pol_Rbc25 PF08292.7 CBK24259.2 - 2.9e-23 82.3 1.6 1.8e-20 73.3 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CBK24259.2 - 1.6e-17 63.3 0.0 2.7e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_S3_C PF00189.15 CBK24260.2 - 8.5e-15 54.7 0.2 1.4e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBK24260.2 - 2.1e-11 43.2 0.2 3.9e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CBK24260.2 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pro_isomerase PF00160.16 CBK24261.2 - 5.6e-50 169.5 0.3 6.2e-50 169.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Diphthamide_syn PF01866.12 CBK24263.2 - 2.6e-106 355.3 0.0 3.1e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EamA PF00892.15 CBK24264.2 - 1.2e-09 38.3 12.9 2.4e-05 24.3 1.5 3.2 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 CBK24264.2 - 0.00084 18.3 13.2 0.35 9.7 9.1 2.1 1 1 0 1 1 1 1 UAA transporter family TGS PF02824.16 CBK24265.2 - 4.2e-23 80.9 0.0 8.1e-23 80.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBK24265.2 - 3.4e-18 65.6 0.0 6.7e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK24265.2 - 7.9e-11 41.4 0.1 7.1e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBK24265.2 - 0.00055 19.8 0.2 0.11 12.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CBK24265.2 - 0.0039 15.9 0.1 0.0098 14.6 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CBK24265.2 - 0.0054 17.2 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein SET PF00856.23 CBK24266.2 - 1.2e-09 38.7 0.0 2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-UBP PF02148.14 CBK24268.2 - 3.6e-20 71.8 26.2 6.7e-17 61.3 7.9 3.4 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 CBK24268.2 - 2.7e-16 59.5 0.3 4.5e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24268.2 - 9.6e-05 21.9 0.6 0.00015 21.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UPF0547 PF10571.4 CBK24268.2 - 0.13 11.9 0.1 0.13 11.9 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 UPF1_Zn_bind PF09416.5 CBK24268.2 - 0.48 10.0 16.9 0.1 12.1 3.1 2.6 3 0 0 3 3 3 0 RNA helicase (UPF2 interacting domain) UCH PF00443.24 CBK24269.2 - 3.1e-11 42.9 0.0 3.4e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24269.2 - 2.8e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8e PF01201.17 CBK24270.2 - 3.6e-30 104.7 0.5 5.6e-30 104.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Dynein_heavy PF03028.10 CBK24273.2 - 0.082 10.9 0.0 0.094 10.7 0.0 1.0 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Glycos_transf_2 PF00535.21 CBK24275.2 - 1.9e-28 99.2 0.0 2.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBK24275.2 - 1.2e-07 31.8 0.0 1.6e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CBK24275.2 - 0.00019 20.7 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 CBK24275.2 - 0.00046 19.3 0.0 0.00078 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBK24275.2 - 0.0072 16.0 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF3842 PF12953.2 CBK24275.2 - 0.034 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Glyco_tranf_2_5 PF13712.1 CBK24275.2 - 0.039 13.1 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family zf-ribbon_3 PF13248.1 CBK24276.2 - 0.0016 17.5 0.4 0.96 8.7 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CBK24276.2 - 0.0035 17.1 0.4 1.4 8.7 0.1 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBK24276.2 - 0.008 15.6 2.4 2.4 7.7 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain YkuI_C PF10388.4 CBK24276.2 - 0.02 14.5 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain TFIIS_C PF01096.13 CBK24276.2 - 0.036 13.6 2.0 2.9 7.5 0.1 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CBK24276.2 - 0.067 13.5 0.6 0.82 10.0 0.2 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Rpr2 PF04032.11 CBK24276.2 - 0.079 12.8 1.0 0.15 11.9 0.7 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.7 CBK24276.2 - 0.09 12.1 2.9 4.1 6.8 0.9 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 CBK24276.2 - 0.096 12.6 3.9 3.6 7.6 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 CBK24276.2 - 0.1 12.2 1.5 2 8.1 1.0 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNL PF05180.7 CBK24276.2 - 0.11 12.2 0.5 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 DNL zinc finger YhfH PF14149.1 CBK24276.2 - 0.11 12.2 0.7 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 YhfH-like protein UPF0547 PF10571.4 CBK24276.2 - 0.21 11.2 3.8 0.33 10.6 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CpXC PF14353.1 CBK24276.2 - 0.25 11.3 4.3 0.69 9.8 1.6 2.6 2 1 1 3 3 2 0 CpXC protein zf-H2C2_2 PF13465.1 CBK24276.2 - 0.27 11.6 3.7 0.32 11.3 0.3 2.5 2 1 0 2 2 2 0 Zinc-finger double domain RNA_POL_M_15KD PF02150.11 CBK24276.2 - 0.3 10.7 3.1 7.2 6.4 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_5 PF13719.1 CBK24276.2 - 0.32 10.6 2.1 3.4 7.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CBK24276.2 - 0.33 10.8 2.1 1.1 9.1 1.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 CBK24276.2 - 0.33 10.4 5.9 2.4 7.7 0.2 2.7 2 1 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_4 PF13717.1 CBK24276.2 - 0.35 10.5 2.4 3.6 7.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 CBK24276.2 - 1.5 8.9 9.5 0.17 12.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C2H2 PF00096.21 CBK24276.2 - 3.2 8.3 6.3 1.2 9.6 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type PHD PF00628.24 CBK24278.2 - 0.00016 21.3 14.3 0.00016 21.3 9.9 2.8 3 0 0 3 3 3 2 PHD-finger Colicin_V PF02674.11 CBK24279.2 - 0.5 10.2 3.9 7.7 6.3 1.0 2.2 2 0 0 2 2 2 0 Colicin V production protein DZR PF12773.2 CBK24280.2 - 0.39 10.5 4.0 1.3 8.8 2.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon Ras PF00071.17 CBK24281.2 - 2.1e-47 160.5 0.3 2.8e-47 160.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK24281.2 - 4.7e-18 65.7 0.0 1.2e-17 64.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK24281.2 - 1.3e-11 44.0 0.1 1.7e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK24281.2 - 0.0001 21.8 0.5 0.00037 19.9 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBK24281.2 - 0.018 14.2 0.0 0.026 13.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.4 CBK24281.2 - 0.028 13.0 0.2 0.037 12.6 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SieB PF14163.1 CBK24282.2 - 0.22 11.0 5.1 0.25 10.8 3.5 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF4131 PF13567.1 CBK24282.2 - 0.58 9.5 5.4 0.62 9.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HSP20 PF00011.16 CBK24283.2 - 2.2e-27 94.9 1.4 2.8e-27 94.5 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 CBK24283.2 - 0.021 14.3 0.7 0.028 13.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PMI_typeI PF01238.16 CBK24284.2 - 3e-91 306.1 0.0 3.6e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 CBK24284.2 - 0.06 12.8 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain MA3 PF02847.12 CBK24285.2 - 5.6e-20 71.1 0.4 1.4e-19 69.8 0.1 1.8 2 0 0 2 2 2 1 MA3 domain AMP-binding PF00501.23 CBK24286.2 - 7.1e-78 261.8 0.0 9e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.16 CBK24288.2 - 8.2e-48 163.1 0.0 1.1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBK24288.2 - 3.6e-06 26.3 0.0 7.5e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Pec_lyase_C PF00544.14 CBK24288.2 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Pectate lyase Herpes_gE PF02480.11 CBK24289.2 - 6.4e-05 21.4 0.4 6.4e-05 21.4 0.3 1.8 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 CBK24289.2 - 9.8e-05 22.0 1.1 0.00021 20.9 0.7 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.1 CBK24289.2 - 0.00055 20.1 2.9 0.00055 20.1 2.0 2.6 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator FAM163 PF15069.1 CBK24289.2 - 0.034 14.7 2.5 0.034 14.7 1.8 2.8 2 1 0 2 2 2 0 FAM163 family TMEM154 PF15102.1 CBK24289.2 - 0.071 12.8 9.6 0.69 9.6 6.7 2.3 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 CBK24289.2 - 0.099 13.0 0.2 0.26 11.6 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF605 PF04652.11 CBK24289.2 - 0.1 11.9 16.4 0.14 11.5 11.4 1.2 1 0 0 1 1 1 0 Vta1 like Met_10 PF02475.11 CBK24290.2 - 1.8e-53 181.1 0.0 2.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBK24290.2 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK24290.2 - 0.0021 18.5 0.0 0.004 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK24290.2 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FmrO PF07091.6 CBK24290.2 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 CBK24290.2 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.6 CBK24290.2 - 0.016 13.9 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.1 CBK24290.2 - 0.024 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 CBK24290.2 - 0.03 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.8 CBK24290.2 - 0.048 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.12 CBK24290.2 - 0.058 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase TehB PF03848.9 CBK24290.2 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB AD PF09793.4 CBK24291.2 - 1.1e-11 44.3 0.1 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain DDOST_48kD PF03345.9 CBK24292.2 - 3.7e-72 243.1 5.8 1.3e-38 132.6 2.4 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta PAXNEB PF05625.6 CBK24293.2 - 1e-20 73.9 0.1 2.4e-20 72.7 0.1 1.6 1 1 0 1 1 1 1 PAXNEB protein DNA_topoisoIV PF00521.15 CBK24295.2 - 3.4e-114 381.9 0.1 5.5e-114 381.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBK24295.2 - 2.9e-20 72.1 0.0 1.1e-19 70.3 0.0 2.0 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CBK24295.2 - 4.5e-14 52.2 0.1 2.3e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 CBK24295.2 - 6.9e-10 38.6 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ERp29 PF07749.7 CBK24295.2 - 0.004 17.7 6.1 0.56 10.8 0.9 4.1 3 0 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Peptidase_C48 PF02902.14 CBK24297.2 - 1.1e-24 87.2 0.9 2.6e-24 86.0 0.6 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain V-SNARE PF05008.10 CBK24298.2 - 0.0044 17.1 0.5 0.0044 17.1 0.3 3.5 1 1 2 3 3 3 1 Vesicle transport v-SNARE protein N-terminus AAA_13 PF13166.1 CBK24298.2 - 0.006 15.1 16.2 0.011 14.2 11.2 1.4 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 CBK24298.2 - 0.0084 15.9 15.7 0.0084 15.9 10.9 2.2 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.4 CBK24298.2 - 0.01 15.8 11.6 0.027 14.4 8.0 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.3 CBK24298.2 - 0.012 15.4 22.0 0.3 10.9 3.2 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NYD-SP28_assoc PF14775.1 CBK24298.2 - 0.017 14.7 1.4 0.017 14.7 1.0 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Tup_N PF08581.5 CBK24298.2 - 0.018 15.2 12.0 0.83 9.8 0.8 2.7 2 0 0 2 2 2 0 Tup N-terminal DivIVA PF05103.8 CBK24298.2 - 0.018 15.1 15.4 0.018 15.1 10.7 2.2 1 1 1 2 2 2 0 DivIVA protein Scaffolding_pro PF11418.3 CBK24298.2 - 0.021 15.1 2.3 0.021 15.1 1.6 2.4 1 1 1 2 2 2 0 Phi29 scaffolding protein DUF3450 PF11932.3 CBK24298.2 - 0.022 14.0 22.2 0.14 11.4 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.20 CBK24298.2 - 0.023 14.8 16.1 0.11 12.6 1.7 2.6 2 0 0 2 2 2 0 Syntaxin Reo_sigmaC PF04582.7 CBK24298.2 - 0.024 13.8 9.6 0.6 9.2 3.4 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 CBK24298.2 - 0.026 14.0 23.7 0.17 11.2 8.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein DUF904 PF06005.7 CBK24298.2 - 0.035 14.4 24.9 16 5.8 14.4 3.2 2 1 0 2 2 1 0 Protein of unknown function (DUF904) FUSC PF04632.7 CBK24298.2 - 0.048 12.0 7.7 0.056 11.8 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.3 CBK24298.2 - 0.063 13.0 18.9 0.037 13.7 2.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 CBK24298.2 - 0.066 12.7 22.7 0.35 10.3 3.2 3.3 1 1 3 4 4 4 0 Septum formation initiator DUF972 PF06156.8 CBK24298.2 - 0.083 13.2 19.2 0.37 11.1 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Hemagglutinin PF00509.13 CBK24298.2 - 0.097 10.8 3.1 0.14 10.2 2.2 1.2 1 0 0 1 1 1 0 Haemagglutinin CCDC92 PF14916.1 CBK24298.2 - 0.099 12.2 0.1 0.099 12.2 0.1 3.4 3 1 0 3 3 3 0 Coiled-coil domain of unknown function GAS PF13851.1 CBK24298.2 - 0.15 11.2 21.4 0.34 10.0 14.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 CBK24298.2 - 0.18 11.5 28.2 1 9.0 12.5 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 CBK24298.2 - 0.22 11.2 16.7 0.35 10.6 1.4 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.2 CBK24298.2 - 0.32 10.8 21.5 0.63 9.8 13.3 2.2 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.3 CBK24298.2 - 0.4 10.5 33.5 1 9.2 8.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding RasGAP_C PF03836.10 CBK24298.2 - 0.45 10.2 15.8 0.45 10.2 9.1 2.3 1 1 0 2 2 2 0 RasGAP C-terminus V_ATPase_I PF01496.14 CBK24298.2 - 0.68 7.7 15.7 2.1 6.0 11.0 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 CBK24298.2 - 0.79 9.2 22.6 1.4 8.4 14.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF2968 PF11180.3 CBK24298.2 - 0.81 9.0 25.9 0.02 14.2 13.2 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF2968) Snapin_Pallidin PF14712.1 CBK24298.2 - 0.86 9.9 18.0 2.7 8.3 1.2 2.7 2 1 1 3 3 2 0 Snapin/Pallidin DUF4140 PF13600.1 CBK24298.2 - 0.97 9.9 13.9 2.5 8.5 4.9 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) MbeD_MobD PF04899.7 CBK24298.2 - 1 9.3 19.9 0.045 13.6 1.6 3.0 3 0 0 3 3 2 0 MbeD/MobD like DUF948 PF06103.6 CBK24298.2 - 1.2 9.0 10.2 13 5.7 3.7 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.4 CBK24298.2 - 1.2 7.7 28.9 0.057 12.1 14.7 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 BRE1 PF08647.6 CBK24298.2 - 1.3 9.0 21.3 5.5 7.0 2.7 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Sec2p PF06428.6 CBK24298.2 - 1.7 8.5 17.5 1.5 8.6 6.2 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.1 CBK24298.2 - 2.4 8.1 25.4 1.1 9.2 10.4 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2203 PF09969.4 CBK24298.2 - 2.9 8.1 8.9 8.3 6.6 3.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) USP8_interact PF08941.5 CBK24298.2 - 3.2 7.0 13.6 1.4 8.1 3.0 2.9 2 1 1 3 3 3 0 USP8 interacting YlqD PF11068.3 CBK24298.2 - 3.6 7.6 19.1 10 6.1 9.2 2.3 1 1 1 2 2 2 0 YlqD protein IncA PF04156.9 CBK24298.2 - 3.7 7.1 32.8 0.86 9.1 4.8 2.3 1 1 1 2 2 2 0 IncA protein Spc24 PF08286.6 CBK24298.2 - 3.8 7.2 21.9 3.1 7.4 6.4 3.4 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CBK24298.2 - 5.1 6.0 27.0 0.73 8.8 12.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 SH3_1 PF00018.23 CBK24299.2 - 6.1e-15 54.3 0.2 8.5e-07 28.2 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CBK24299.2 - 1.8e-07 30.6 0.2 0.0061 16.1 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CBK24299.2 - 2.7e-06 26.7 0.0 0.00037 19.9 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_4 PF06347.8 CBK24299.2 - 0.00017 21.0 0.8 0.056 12.9 0.1 2.2 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_3 PF08239.6 CBK24299.2 - 0.0054 16.9 0.5 2.2 8.5 0.1 2.2 2 0 0 2 2 2 2 Bacterial SH3 domain DUF2862 PF11061.3 CBK24299.2 - 0.019 14.6 1.1 0.047 13.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) SH3_6 PF12913.2 CBK24299.2 - 0.078 12.2 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type DUF1713 PF08213.6 CBK24300.2 - 6.4e-06 25.6 17.6 7.2e-06 25.5 12.2 1.1 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) POPLD PF08170.7 CBK24300.2 - 0.49 10.2 4.5 0.47 10.3 3.1 1.0 1 0 0 1 1 1 0 POPLD (NUC188) domain GTP_EFTU PF00009.22 CBK24302.2 - 1.8e-56 190.5 0.0 2.5e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK24302.2 - 1.7e-33 114.6 0.1 5.4e-33 113.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK24302.2 - 5.8e-10 39.1 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK24302.2 - 0.00011 22.1 0.1 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK24302.2 - 0.032 13.3 0.5 0.075 12.1 0.1 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK24302.2 - 0.043 14.3 0.4 0.64 10.5 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein He_PIG PF05345.7 CBK24303.2 - 0.0023 17.8 0.0 0.0074 16.2 0.0 1.9 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.15 CBK24303.2 - 0.011 16.0 4.5 0.02 15.2 0.6 2.5 2 0 0 2 2 2 0 Sushi domain (SCR repeat) LRRC37AB_C PF14914.1 CBK24303.2 - 0.11 11.9 0.2 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain P12 PF12669.2 CBK24303.2 - 0.45 10.7 2.4 0.97 9.6 1.6 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family DNA_pol_B_2 PF03175.8 CBK24304.2 - 6.9e-08 31.5 9.0 0.00084 18.1 0.2 3.5 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral HA2 PF04408.18 CBK24305.2 - 6.2e-27 93.6 0.0 1.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK24305.2 - 2.8e-26 91.5 0.0 8.4e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK24305.2 - 6.9e-14 51.4 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK24305.2 - 3.2e-07 30.0 0.1 7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CBK24305.2 - 1.2e-05 24.3 0.0 2.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBK24305.2 - 0.0002 21.4 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBK24305.2 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBK24305.2 - 0.0035 17.0 0.0 0.009 15.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CBK24305.2 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK24305.2 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HAD_2 PF13419.1 CBK24305.2 - 0.046 13.9 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NB-ARC PF00931.17 CBK24305.2 - 0.059 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 CBK24305.2 - 0.07 12.9 0.0 3.3 7.4 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CBK24305.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK24305.2 - 0.11 12.7 0.2 3.4 7.9 0.1 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CBK24305.2 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CBK24305.2 - 0.14 11.8 0.1 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 NACHT domain CTP_synth_N PF06418.9 CBK24306.2 - 6.5e-125 415.7 0.0 8.5e-125 415.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CBK24306.2 - 2.9e-48 163.8 0.0 4.6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBK24306.2 - 4e-09 36.2 0.2 1e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CBK24306.2 - 7.4e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2726 PF10881.3 CBK24306.2 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2726) HEAT PF02985.17 CBK24307.2 - 0.00016 21.4 0.5 0.17 12.0 0.0 5.1 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 CBK24307.2 - 0.013 15.7 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats YfbU PF03887.9 CBK24308.2 - 0.023 14.2 0.0 0.22 11.1 0.0 2.3 2 1 1 3 3 3 0 YfbU domain HA2 PF04408.18 CBK24309.2 - 7.8e-28 96.4 0.0 1.8e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK24309.2 - 5.9e-26 90.5 0.0 1.5e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK24309.2 - 1.7e-13 50.1 0.0 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK24309.2 - 3.2e-07 29.9 0.1 7.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CBK24309.2 - 1.3e-05 24.2 0.0 2.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBK24309.2 - 0.0002 21.4 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBK24309.2 - 0.0015 17.9 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBK24309.2 - 0.0032 17.2 0.0 0.0094 15.6 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBK24309.2 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK24309.2 - 0.023 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CBK24309.2 - 0.067 13.0 0.0 3 7.6 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 CBK24309.2 - 0.069 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CBK24309.2 - 0.07 13.4 0.2 3.5 7.9 0.1 2.8 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 CBK24309.2 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBK24309.2 - 0.11 12.8 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBK24309.2 - 0.11 12.3 0.1 2.3 8.1 0.1 2.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CBK24309.2 - 0.13 11.5 0.0 0.92 8.7 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activ_2 PF14532.1 CBK24309.2 - 0.13 12.2 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CBK24309.2 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DnaJ PF00226.26 CBK24310.2 - 1.1e-18 66.7 1.4 2e-18 65.8 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF501 PF04417.7 CBK24310.2 - 0.58 9.9 4.4 0.97 9.2 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) V_ATPase_I PF01496.14 CBK24310.2 - 0.59 7.9 6.2 0.64 7.7 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dict-STAT-coil PF09267.5 CBK24310.2 - 1.8 8.8 5.6 1.3 9.2 0.3 2.2 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil DUF342 PF03961.8 CBK24310.2 - 7.1 4.9 8.0 8.6 4.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) tRNA_bind PF01588.15 CBK24311.2 - 4.4e-27 93.7 0.0 8.3e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DEAD PF00270.24 CBK24312.2 - 1.7e-42 144.8 0.5 3e-42 143.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24312.2 - 2.4e-20 72.1 0.2 2.4e-19 68.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CBK24312.2 - 0.00086 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CBK24312.2 - 0.015 14.9 0.2 0.038 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.1 CBK24312.2 - 0.039 13.0 0.0 0.091 11.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 CBK24312.2 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.12 CBK24313.2 - 2e-25 88.9 3.7 2.5e-25 88.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CBK24313.2 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 KOW motif Pox_J1 PF03338.10 CBK24313.2 - 0.017 14.8 0.1 0.06 13.0 0.0 1.8 1 1 1 2 2 2 0 Poxvirus J1 protein WD40 PF00400.27 CBK24314.2 - 1.9e-46 154.3 23.6 5.8e-11 41.8 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CBK24314.2 - 5.2e-05 21.5 5.5 0.25 9.4 0.1 3.7 2 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK24314.2 - 0.00011 21.0 4.4 0.0062 15.3 0.1 3.7 1 1 3 5 5 5 2 Nup133 N terminal like SH3_9 PF14604.1 CBK24315.2 - 1.3e-13 50.2 0.0 2.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBK24315.2 - 3.3e-13 48.8 0.1 6.9e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBK24315.2 - 1.1e-11 44.0 0.0 2.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 CBK24315.2 - 9.4e-08 31.8 5.3 8.9e-07 28.6 0.4 2.5 1 1 1 2 2 2 2 BAR domain TP_methylase PF00590.15 CBK24316.2 - 7e-21 74.8 0.0 1.3e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.20 CBK24317.2 - 1.6e-67 227.4 0.0 1.8e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24317.2 - 1.5e-29 102.8 0.0 2.1e-29 102.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24317.2 - 9.2e-05 21.5 0.0 0.0064 15.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 CBK24317.2 - 0.00079 19.2 0.1 0.0019 17.9 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBK24317.2 - 0.016 14.0 0.2 0.028 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBK24317.2 - 0.026 13.6 0.0 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBK24317.2 - 0.11 12.0 0.2 0.22 11.0 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase zf-RING_2 PF13639.1 CBK24318.2 - 5.2e-05 22.9 15.5 8.7e-05 22.2 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 CBK24318.2 - 9.8e-05 22.2 10.4 0.00056 19.8 7.2 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 CBK24318.2 - 0.00015 21.7 6.5 0.00027 20.9 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBK24318.2 - 0.0007 19.3 5.3 0.0013 18.5 3.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBK24318.2 - 0.0042 17.0 12.2 0.0072 16.3 8.4 1.4 1 0 0 1 1 1 1 RING-variant domain MRL1 PF13003.2 CBK24318.2 - 0.014 15.1 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 zf-C3HC4 PF00097.20 CBK24318.2 - 0.078 12.6 14.6 0.15 11.7 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK24318.2 - 0.72 9.5 13.3 2.1 8.1 9.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CBK24318.2 - 1.3 9.0 11.6 0.061 13.3 3.8 1.8 2 0 0 2 2 2 0 RING-like domain CS PF04969.11 CBK24319.2 - 6.9e-07 29.7 0.9 1.8e-06 28.4 0.1 2.1 2 1 0 2 2 2 1 CS domain ATP-synt_C PF00137.16 CBK24320.2 - 7.7e-28 96.1 32.0 1.7e-16 59.8 8.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 CBK24320.2 - 0.018 14.5 0.7 0.018 14.5 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) BofA PF07441.6 CBK24320.2 - 0.22 11.5 9.7 0.93 9.5 1.2 2.4 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA KRTAP PF11759.3 CBK24320.2 - 0.23 11.7 7.4 0.46 10.7 3.0 2.2 2 0 0 2 2 2 0 Keratin-associated matrix Flp_Fap PF04964.9 CBK24320.2 - 1.7 8.3 5.8 8.3 6.0 0.1 2.8 2 0 0 2 2 2 0 Flp/Fap pilin component FAIM1 PF06905.8 CBK24321.2 - 4.3e-05 22.7 0.1 6.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Astro_capsid PF03115.9 CBK24321.2 - 0.02 13.1 5.6 0.023 13.0 3.9 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CBK24321.2 - 1.1 7.0 22.9 1.3 6.8 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CBK24321.2 - 1.7 7.0 23.8 2.1 6.7 16.5 1.1 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 CBK24321.2 - 1.8 8.0 10.5 2.5 7.5 7.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CBK24321.2 - 2.7 5.9 11.0 2.8 5.8 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CBK24321.2 - 2.7 7.8 13.0 3.9 7.2 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VID27 PF08553.5 CBK24321.2 - 4.7 5.3 13.1 5.3 5.1 9.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Na_trans_assoc PF06512.8 CBK24321.2 - 8.7 6.2 18.8 12 5.7 13.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Euplotes_phero PF05842.6 CBK24322.2 - 0.024 14.9 17.3 0.48 10.7 0.8 4.8 1 1 3 4 4 4 0 Euplotes octocarinatus mating pheromone protein YpjP PF14005.1 CBK24322.2 - 0.33 10.6 14.2 0.94 9.2 0.7 3.5 1 1 2 3 3 3 0 YpjP-like protein COMPASS-Shg1 PF05205.7 CBK24322.2 - 6.3 7.1 10.9 2.5 8.4 3.5 2.2 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Pox_A9 PF04835.7 CBK24323.2 - 0.17 11.7 0.8 0.26 11.2 0.5 1.3 1 0 0 1 1 1 0 A9 protein conserved region SDA1 PF05285.7 CBK24325.2 - 0.00061 19.1 22.7 0.00067 19.0 15.7 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 CBK24325.2 - 0.0042 15.2 14.6 0.0049 14.9 10.1 1.1 1 0 0 1 1 1 1 CDC45-like protein MIP-T3 PF10243.4 CBK24325.2 - 0.039 12.4 25.3 0.039 12.4 17.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CBK24325.2 - 0.055 11.9 33.7 0.066 11.6 23.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF2413 PF10310.4 CBK24325.2 - 0.097 11.4 20.7 0.16 10.7 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 CBK24325.2 - 0.18 11.6 3.5 0.22 11.3 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CBK24325.2 - 0.24 9.0 14.7 0.26 8.9 10.2 1.1 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 CBK24325.2 - 0.47 9.5 35.1 0.73 8.9 24.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.1 CBK24325.2 - 0.59 8.5 9.2 0.78 8.1 6.4 1.2 1 0 0 1 1 1 0 Raftlin CENP-T PF15511.1 CBK24325.2 - 0.74 8.9 29.2 0.99 8.5 20.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RR_TM4-6 PF06459.7 CBK24325.2 - 0.75 9.6 25.4 1.1 9.0 17.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CBK24325.2 - 3 6.7 7.0 4.4 6.2 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDRGK PF09756.4 CBK24325.2 - 3.1 7.1 28.6 6.1 6.2 19.8 1.5 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.2 CBK24325.2 - 3.2 5.3 13.1 4 5.0 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CBK24325.2 - 3.8 6.8 32.9 5.6 6.2 22.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2146 PF10220.4 CBK24325.2 - 5.3 4.8 13.9 6.5 4.5 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) eIF-3c_N PF05470.7 CBK24325.2 - 7.8 4.4 17.3 9.6 4.1 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Gcd10p PF04189.8 CBK24326.2 - 1.7e-52 178.4 0.3 4.1e-52 177.1 0.2 1.5 1 1 0 1 1 1 1 Gcd10p family HSP70 PF00012.15 CBK24327.2 - 3.1e-61 207.0 0.2 3.9e-61 206.7 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24327.2 - 2.6e-14 52.5 1.5 5.3e-14 51.5 1.1 1.5 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.6 CBK24327.2 - 2.2e-06 26.8 0.6 7.3e-05 21.8 0.4 2.1 1 1 0 1 1 1 1 StbA protein DUF2237 PF09996.4 CBK24327.2 - 0.019 14.4 0.3 0.04 13.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) FtsA PF14450.1 CBK24327.2 - 0.027 14.2 5.7 18 5.1 0.1 4.2 2 2 0 2 2 2 0 Cell division protein FtsA DDR PF08841.5 CBK24327.2 - 0.049 12.4 0.0 3 6.5 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF1654 PF07867.6 CBK24327.2 - 0.06 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DMAP1 PF05499.7 CBK24327.2 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF373 PF04123.8 CBK24329.2 - 0.16 10.9 1.3 0.21 10.5 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phos_pyr_kin PF08543.7 CBK24330.2 - 1.2e-82 276.8 0.0 1.7e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CBK24330.2 - 1.2e-21 77.4 0.4 2.3e-21 76.5 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CBK24330.2 - 2.3e-11 43.3 0.0 1.2e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GILT PF03227.11 CBK24331.2 - 6.8e-22 77.3 0.1 1.3e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DEAD PF00270.24 CBK24332.2 - 6.3e-41 139.6 0.0 9.1e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24332.2 - 3.6e-25 87.6 0.1 6.3e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Abhydrolase_5 PF12695.2 CBK24334.2 - 8.6e-17 61.2 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBK24334.2 - 8.8e-07 29.0 0.0 0.0016 18.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBK24334.2 - 2e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 CBK24334.2 - 0.00013 21.5 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CBK24334.2 - 0.0022 17.2 0.0 0.005 16.0 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBK24334.2 - 0.026 14.0 0.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 CBK24334.2 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family TFIIS_C PF01096.13 CBK24335.2 - 2.1e-18 65.6 3.6 2.1e-18 65.6 2.5 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CBK24335.2 - 1.1e-05 24.9 0.6 1.1e-05 24.9 0.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CBK24335.2 - 0.0012 18.6 1.1 0.0012 18.6 0.7 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain Terminase_GpA PF05876.7 CBK24335.2 - 0.0017 16.8 1.7 0.0017 16.8 1.2 1.5 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 CBK24335.2 - 0.0028 17.9 5.1 0.2 12.0 0.4 2.2 2 0 0 2 2 2 2 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.3 CBK24335.2 - 0.0041 16.4 1.7 0.0041 16.4 1.2 1.9 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain Mut7-C PF01927.11 CBK24335.2 - 0.0078 16.1 0.7 0.01 15.7 0.5 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain TF_Zn_Ribbon PF08271.7 CBK24335.2 - 0.012 14.9 0.8 0.012 14.9 0.5 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zf-DNA_Pol PF08996.5 CBK24335.2 - 0.012 14.9 1.5 0.044 13.1 0.4 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DZR PF12773.2 CBK24335.2 - 0.026 14.3 10.6 0.046 13.5 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 CBK24335.2 - 0.032 13.9 5.7 1.7 8.4 0.3 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.7 CBK24335.2 - 0.099 12.4 7.5 0.72 9.6 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbons PyrI_C PF02748.10 CBK24335.2 - 0.11 11.9 3.4 1.2 8.6 0.3 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF329 PF03884.9 CBK24335.2 - 0.15 11.5 6.5 7.9 6.1 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF329) Zn_ribbon_recom PF13408.1 CBK24335.2 - 0.22 11.7 5.5 0.97 9.7 0.1 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.4 CBK24335.2 - 0.4 10.4 0.0 0.4 10.4 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF164 PF02591.10 CBK24335.2 - 0.71 9.7 8.5 1.9 8.3 0.9 2.8 2 1 0 2 2 2 0 Putative zinc ribbon domain DiS_P_DiS PF06750.8 CBK24335.2 - 1.9 8.3 5.3 0.26 11.0 0.6 2.0 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Tnp_zf-ribbon_2 PF13842.1 CBK24335.2 - 4.9 7.6 17.2 4.7 7.7 0.4 4.0 3 1 1 4 4 4 0 DDE_Tnp_1-like zinc-ribbon zf-BED PF02892.10 CBK24335.2 - 5.2 6.9 7.3 4.8 7.0 0.1 2.9 2 1 1 3 3 3 0 BED zinc finger Lung_7-TM_R PF06814.8 CBK24336.2 - 5.7e-18 64.8 1.6 7.7e-18 64.4 1.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor zf-RING_2 PF13639.1 CBK24337.2 - 1.4e-13 50.4 13.9 2.7e-13 49.4 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBK24337.2 - 2.7e-12 46.4 11.2 6.2e-12 45.3 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBK24337.2 - 2.8e-10 39.6 11.9 4.9e-10 38.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK24337.2 - 8.3e-10 38.1 10.8 1.4e-09 37.4 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBK24337.2 - 1.9e-09 37.2 8.5 4.9e-09 35.9 6.0 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBK24337.2 - 1e-07 31.5 5.1 1.2e-07 31.3 1.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBK24337.2 - 9e-07 28.5 12.5 3.6e-06 26.5 8.8 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBK24337.2 - 6.7e-06 26.1 11.0 2e-05 24.5 7.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 CBK24337.2 - 0.00049 20.0 0.0 0.00091 19.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 CBK24337.2 - 0.0014 18.4 4.7 0.0025 17.5 3.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CBK24337.2 - 0.012 15.4 8.2 0.031 14.1 5.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CBK24337.2 - 0.015 14.7 8.2 0.027 14.0 5.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CBK24337.2 - 0.035 13.6 10.9 0.093 12.2 7.5 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CBK24337.2 - 0.043 13.4 12.8 0.12 11.9 6.9 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 CBK24337.2 - 0.049 13.1 5.0 0.55 9.7 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-MIZ PF02891.15 CBK24337.2 - 0.19 11.2 12.0 0.33 10.5 8.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_1 PF14446.1 CBK24337.2 - 0.31 10.8 6.5 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 CBK24337.2 - 0.91 9.3 8.7 1.7 8.5 6.0 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-P11 PF03854.9 CBK24337.2 - 1.4 8.4 9.0 22 4.6 6.3 2.3 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.2 CBK24337.2 - 1.5 8.7 10.2 11 5.8 7.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CBK24337.2 - 4.2 7.0 7.1 4.5 6.9 0.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CBK24338.2 - 0.0049 16.0 0.4 0.0073 15.4 0.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBK24338.2 - 0.0094 15.4 0.5 0.016 14.7 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBK24338.2 - 0.029 14.1 1.0 0.049 13.4 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 CBK24338.2 - 0.089 12.5 1.8 2.1 8.2 1.6 2.3 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-RanBP PF00641.13 CBK24338.2 - 0.11 11.6 5.5 0.19 10.8 3.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others OrfB_Zn_ribbon PF07282.6 CBK24338.2 - 0.11 12.2 0.8 0.25 11.0 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 CBK24338.2 - 5 6.7 6.7 1.2e+02 2.3 3.0 3.1 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NAD_binding_5 PF07994.7 CBK24339.2 - 6.8e-111 370.4 0.0 8e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CBK24339.2 - 2.3e-44 149.7 0.0 4.4e-44 148.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Asp-B-Hydro_N PF05279.6 CBK24340.2 - 0.027 14.3 17.5 0.036 13.9 12.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 CBK24340.2 - 0.12 11.7 15.5 0.17 11.2 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 CBK24340.2 - 0.12 11.3 2.7 0.15 11.0 1.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 CBK24340.2 - 0.22 11.3 15.0 0.28 11.0 10.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.7 CBK24340.2 - 0.28 10.4 16.0 0.33 10.1 11.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CBK24340.2 - 0.32 8.8 15.2 0.35 8.7 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CBK24340.2 - 0.34 9.3 15.9 0.37 9.2 11.0 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 CBK24340.2 - 1 8.4 15.4 1.4 7.9 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Zip PF02535.17 CBK24340.2 - 1.5 7.7 3.9 1.7 7.5 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.5 CBK24340.2 - 1.7 8.6 16.4 3.2 7.7 11.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CBK24340.2 - 1.9 8.1 7.0 2.4 7.9 4.8 1.3 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 CBK24340.2 - 2.7 7.4 14.9 4.2 6.8 10.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNase_H2-Ydr279 PF09468.5 CBK24340.2 - 3.3 6.8 12.4 21 4.1 8.2 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) CPSF100_C PF13299.1 CBK24340.2 - 3.3 7.8 7.5 5 7.2 5.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.9 CBK24340.2 - 3.5 5.5 10.0 4.4 5.2 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein COG7 PF10191.4 CBK24341.2 - 1.9e-25 88.9 5.4 2.1e-25 88.8 3.7 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DUF2730 PF10805.3 CBK24341.2 - 0.03 14.0 1.7 0.37 10.5 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.7 CBK24341.2 - 0.14 11.9 4.1 0.26 11.0 2.8 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 CBK24341.2 - 0.24 10.9 9.9 0.14 11.6 3.7 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spectrin PF00435.16 CBK24341.2 - 0.36 11.1 4.9 0.63 10.3 0.7 2.5 1 1 1 2 2 2 0 Spectrin repeat Cauli_DNA-bind PF03310.8 CBK24341.2 - 2.5 7.9 6.8 3.2 7.6 0.8 2.6 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein Ribosomal_L14 PF00238.14 CBK24342.2 - 9.1e-35 119.0 0.0 1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 CBK24343.2 - 9.5e-21 74.1 0.0 3.1e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBK24343.2 - 2.5e-07 30.6 0.2 1.1e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CBK24343.2 - 1.1e-06 27.9 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBK24343.2 - 0.006 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CBK24343.2 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 CBK24343.2 - 0.048 12.7 0.3 0.078 12.1 0.2 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_ser-thr_kin PF05445.6 CBK24343.2 - 0.07 11.9 0.4 0.11 11.3 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RE_SinI PF09570.5 CBK24343.2 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease DUF1664 PF07889.7 CBK24344.2 - 0.0086 15.8 20.1 0.016 15.0 1.8 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 CBK24344.2 - 0.14 12.0 25.3 0.044 13.6 7.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SIM_C PF06621.7 CBK24344.2 - 0.2 11.1 1.8 0.35 10.4 1.2 1.3 1 0 0 1 1 1 0 Single-minded protein C-terminus DUF972 PF06156.8 CBK24344.2 - 2 8.7 18.5 0.039 14.3 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Anthrax_toxA PF03497.11 CBK24344.2 - 3.6 7.3 9.0 0.4 10.4 1.5 2.0 1 1 1 2 2 2 0 Anthrax toxin LF subunit HAUS6_N PF14661.1 CBK24344.2 - 4.8 6.4 18.6 0.35 10.1 6.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus He_PIG PF05345.7 CBK24346.2 - 9.5e-27 92.7 46.1 1.1e-05 25.3 0.6 7.5 7 0 0 7 7 7 6 Putative Ig domain I-set PF07679.11 CBK24346.2 - 0.00076 19.2 6.9 5.8 6.8 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain Shisa PF13908.1 CBK24346.2 - 0.0018 18.4 0.8 0.0035 17.5 0.6 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 CBK24346.2 - 0.013 15.0 0.2 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK24346.2 - 0.074 13.0 10.5 1.6 8.7 0.1 4.7 5 0 0 5 5 5 0 Hormone receptor domain PGP_phosphatase PF09419.5 CBK24347.2 - 1.6e-32 112.1 0.0 2.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CBK24347.2 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBK24347.2 - 9.8e-06 26.1 0.0 0.024 15.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBK24347.2 - 0.081 13.0 0.1 0.36 10.9 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK24347.2 - 0.082 13.1 0.0 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 CBK24348.2 - 0.013 15.3 2.7 1.9 8.5 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.27 CBK24349.2 - 0.0022 17.7 0.0 1.6 8.7 0.0 3.3 3 1 0 3 3 3 2 WD domain, G-beta repeat A_deaminase PF00962.17 CBK24350.2 - 1.2e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.15 CBK24350.2 - 0.0022 17.7 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Pkinase PF00069.20 CBK24351.2 - 3.2e-40 137.9 0.0 3.8e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24351.2 - 5.4e-27 94.5 0.0 6.1e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24351.2 - 0.0049 15.8 0.0 0.012 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBK24351.2 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ogr_Delta PF04606.7 CBK24351.2 - 0.035 13.7 0.2 0.091 12.4 0.0 1.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger RIO1 PF01163.17 CBK24351.2 - 0.11 11.8 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CBK24351.2 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family G6PD_C PF02781.11 CBK24352.2 - 2.6e-118 394.1 0.0 3.4e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CBK24352.2 - 2.1e-54 184.5 0.0 6.1e-54 183.0 0.0 1.7 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CASP_C PF08172.7 CBK24353.2 - 3.9e-06 26.0 7.5 3.9e-06 26.0 5.2 2.4 2 2 0 2 2 2 1 CASP C terminal Filament PF00038.16 CBK24353.2 - 2.6e-05 23.8 21.4 0.0053 16.2 2.4 3.1 2 1 1 3 3 3 3 Intermediate filament protein Reo_sigmaC PF04582.7 CBK24353.2 - 0.00077 18.7 6.6 0.0012 18.1 0.4 2.5 2 1 0 2 2 2 1 Reovirus sigma C capsid protein FlgN PF05130.7 CBK24353.2 - 0.0024 18.1 13.0 0.058 13.6 1.7 2.5 2 1 0 2 2 2 2 FlgN protein DUF2046 PF09755.4 CBK24353.2 - 0.0033 16.3 2.4 0.0033 16.3 1.7 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF4200 PF13863.1 CBK24353.2 - 0.011 15.7 21.9 0.33 10.9 3.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 CBK24353.2 - 0.02 13.8 11.2 0.074 11.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 CBK24353.2 - 0.061 13.4 14.9 0.28 11.3 0.5 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CBK24353.2 - 0.079 12.5 22.5 0.058 12.9 7.2 2.8 2 1 0 2 2 2 0 IncA protein GAS PF13851.1 CBK24353.2 - 0.12 11.5 19.4 1.1 8.3 2.8 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.7 CBK24353.2 - 0.18 11.1 24.0 0.2 10.9 5.5 3.3 2 1 1 3 3 3 0 PspA/IM30 family PhaP_Bmeg PF09602.5 CBK24353.2 - 0.19 11.5 4.5 2.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CagZ PF09053.5 CBK24353.2 - 0.23 10.7 2.1 2.4 7.4 0.1 2.2 1 1 1 2 2 2 0 CagZ HsbA PF12296.3 CBK24353.2 - 0.26 11.1 4.6 2.4 8.0 0.3 2.8 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Ax_dynein_light PF10211.4 CBK24353.2 - 0.3 10.8 19.0 0.16 11.8 2.0 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain ADIP PF11559.3 CBK24353.2 - 0.34 10.7 23.7 0.57 10.0 2.4 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 CBK24353.2 - 0.57 10.0 21.3 2.6 7.9 2.3 3.1 2 1 0 2 2 2 0 Tropomyosin like Nexin_C PF08628.7 CBK24353.2 - 0.62 10.1 5.2 1 9.4 0.1 2.7 3 0 0 3 3 2 0 Sorting nexin C terminal Mod_r PF07200.8 CBK24353.2 - 0.65 9.9 16.1 0.16 11.8 0.6 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF2407_C PF13373.1 CBK24353.2 - 0.95 9.3 6.2 0.43 10.4 0.8 2.5 2 1 0 2 2 2 0 DUF2407 C-terminal domain bZIP_1 PF00170.16 CBK24353.2 - 1 9.3 22.4 0.64 10.0 0.3 4.8 3 2 2 5 5 5 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 CBK24353.2 - 1.2 8.8 22.8 5.7 6.6 1.9 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein AbiH PF14253.1 CBK24353.2 - 1.4 8.4 6.8 0.26 10.8 1.9 1.7 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Mnd1 PF03962.10 CBK24353.2 - 1.4 8.4 21.4 0.15 11.6 3.1 3.0 2 1 0 2 2 2 0 Mnd1 family DUF724 PF05266.9 CBK24353.2 - 1.6 8.2 15.9 0.61 9.6 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) RGS PF00615.14 CBK24353.2 - 1.6 8.8 5.5 0.99 9.5 1.0 2.5 2 1 1 3 3 3 0 Regulator of G protein signaling domain DUF2968 PF11180.3 CBK24353.2 - 1.8 7.8 18.0 0.29 10.5 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2968) HAUS5 PF14817.1 CBK24353.2 - 1.9 6.9 14.3 0.26 9.7 3.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 OmpH PF03938.9 CBK24353.2 - 2 8.3 21.5 0.13 12.1 3.5 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.5 CBK24353.2 - 2 8.6 16.8 2.2 8.5 0.7 3.4 3 0 0 3 3 3 0 Tup N-terminal TBPIP PF07106.8 CBK24353.2 - 2.2 7.8 13.1 6.9 6.1 0.4 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 CBK24353.2 - 2.3 7.5 8.6 5.4 6.3 0.1 3.0 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Striatin PF08232.7 CBK24353.2 - 2.8 8.2 19.0 1.7 8.9 0.5 3.6 3 1 0 3 3 3 0 Striatin family Occludin_ELL PF07303.8 CBK24353.2 - 3.7 8.3 13.5 1 10.1 0.4 3.4 3 1 1 4 4 4 0 Occludin homology domain FUSC PF04632.7 CBK24353.2 - 4.4 5.6 8.3 1.2 7.4 2.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF2317 PF10079.4 CBK24353.2 - 5.3 5.5 11.1 1.7 7.1 1.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4618 PF15397.1 CBK24353.2 - 5.4 6.2 13.1 6 6.1 0.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) Phage_Mu_Gam PF07352.7 CBK24353.2 - 7.4 6.0 11.6 0.24 10.9 1.9 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein YlqD PF11068.3 CBK24353.2 - 8.9 6.3 12.4 1.9 8.5 0.8 3.0 2 1 1 3 3 3 0 YlqD protein DUF342 PF03961.8 CBK24353.2 - 9.1 4.5 15.5 6 5.1 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF4259 PF14078.1 CBK24353.2 - 9.7 6.7 7.8 1.6 9.1 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4259) PUL PF08324.6 CBK24354.2 - 0.0028 16.5 2.4 0.0028 16.5 1.7 1.9 2 1 0 2 2 2 1 PUL domain DUF342 PF03961.8 CBK24354.2 - 0.0051 15.2 10.1 0.0065 14.9 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF4164 PF13747.1 CBK24354.2 - 0.011 15.8 8.8 0.011 15.8 6.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF641 PF04859.7 CBK24354.2 - 0.011 15.4 7.8 0.011 15.4 5.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.17 CBK24354.2 - 0.019 14.9 6.1 0.019 14.9 4.2 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 CBK24354.2 - 0.034 13.3 21.1 0.26 10.4 7.6 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3209 PF11483.3 CBK24354.2 - 0.14 12.4 2.5 0.11 12.7 0.7 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3209) Enkurin PF13864.1 CBK24354.2 - 0.15 12.2 13.8 1.9 8.7 0.3 2.2 2 0 0 2 2 2 0 Calmodulin-binding DivIVA PF05103.8 CBK24354.2 - 0.17 11.8 15.4 0.085 12.9 1.0 3.2 2 1 1 3 3 3 0 DivIVA protein TBPIP PF07106.8 CBK24354.2 - 0.23 11.0 16.5 0.35 10.3 7.2 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 CBK24354.2 - 0.29 10.3 14.5 0.053 12.7 5.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) PDDEXK_2 PF12784.2 CBK24354.2 - 0.44 9.6 9.3 0.41 9.7 5.0 1.9 1 1 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DUF972 PF06156.8 CBK24354.2 - 0.46 10.8 20.2 0.53 10.6 3.9 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF972) DUF4414 PF14377.1 CBK24354.2 - 0.47 10.4 7.6 0.44 10.4 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4414) Atg14 PF10186.4 CBK24354.2 - 0.5 9.2 20.6 0.051 12.5 8.8 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ARD PF03079.9 CBK24354.2 - 0.6 10.0 4.1 0.27 11.1 0.4 1.9 2 0 0 2 2 2 0 ARD/ARD' family CCDC155 PF14662.1 CBK24354.2 - 0.7 9.4 24.0 0.069 12.7 11.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 CDC37_N PF03234.9 CBK24354.2 - 0.76 10.0 14.7 14 5.9 10.2 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Cep57_MT_bd PF06657.8 CBK24354.2 - 0.99 9.3 22.8 1.9 8.4 3.0 4.2 2 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.4 CBK24354.2 - 1.2 9.4 9.5 2.6 8.2 2.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.6 CBK24354.2 - 1.2 9.1 14.7 0.079 12.9 5.9 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Bap31 PF05529.7 CBK24354.2 - 1.5 8.2 12.2 2.4 7.5 3.9 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Rootletin PF15035.1 CBK24354.2 - 1.6 8.7 18.1 14 5.6 12.6 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 CBK24354.2 - 1.7 6.9 15.6 18 3.6 11.1 1.8 1 1 0 1 1 1 0 AAA domain FliT PF05400.8 CBK24354.2 - 1.8 9.0 12.9 0.38 11.1 5.6 2.3 2 2 1 3 3 2 0 Flagellar protein FliT DivIC PF04977.10 CBK24354.2 - 1.8 8.1 14.7 0.64 9.5 3.9 3.7 2 1 1 3 3 3 0 Septum formation initiator bZIP_1 PF00170.16 CBK24354.2 - 1.9 8.5 19.2 0.42 10.6 3.4 4.5 2 2 3 5 5 5 0 bZIP transcription factor ADIP PF11559.3 CBK24354.2 - 2 8.2 20.0 0.078 12.8 7.7 2.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBK24354.2 - 2.8 7.5 25.4 54 3.3 17.6 2.2 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 CBK24354.2 - 3.9 6.4 21.5 2.6 6.9 9.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CBK24354.2 - 5.9 6.6 20.3 0.23 11.1 8.3 2.5 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Kinesin-relat_1 PF12711.2 CBK24354.2 - 8 6.9 13.8 4.1 7.8 4.9 3.1 1 1 3 4 4 3 0 Kinesin motor Tropomyosin_1 PF12718.2 CBK24354.2 - 8.3 6.2 24.6 0.45 10.3 10.9 2.4 1 1 2 3 3 3 0 Tropomyosin like DUF4140 PF13600.1 CBK24354.2 - 9.2 6.7 13.3 8.4 6.8 0.8 3.2 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 CBK24354.2 - 9.4 6.0 21.0 1.9 8.2 9.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SHQ1 PF04925.10 CBK24355.2 - 5.7e-51 172.6 3.4 6.6e-51 172.4 2.3 1.0 1 0 0 1 1 1 1 SHQ1 protein zf-HIT PF04438.11 CBK24357.2 - 1.9e-09 36.9 1.6 1.9e-09 36.9 1.1 2.6 3 0 0 3 3 3 1 HIT zinc finger zf-CCHC PF00098.18 CBK24357.2 - 0.00052 19.8 2.5 0.00052 19.8 1.8 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF2981 PF11200.3 CBK24357.2 - 0.039 13.0 1.5 0.06 12.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) zf-CCHC_5 PF14787.1 CBK24357.2 - 0.046 13.1 1.3 0.15 11.6 0.9 1.9 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 CBK24357.2 - 0.047 13.1 0.8 0.047 13.1 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle FlaG PF03646.10 CBK24357.2 - 0.054 13.6 4.3 0.11 12.6 3.0 1.4 1 0 0 1 1 1 0 FlaG protein DUF4404 PF14357.1 CBK24357.2 - 0.16 12.4 2.7 0.32 11.4 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PI3_PI4_kinase PF00454.22 CBK24359.2 - 7.7e-57 192.4 0.6 1.7e-56 191.3 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CBK24359.2 - 1.1e-47 162.7 0.7 3.1e-47 161.2 0.5 1.8 1 0 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 CBK24359.2 - 9.4e-24 83.4 3.0 9.6e-23 80.1 1.3 3.1 2 0 0 2 2 2 1 Rapamycin binding domain DUF3385 PF11865.3 CBK24359.2 - 4.5e-18 65.6 0.1 4.5e-18 65.6 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) FATC PF02260.15 CBK24359.2 - 3.1e-10 39.2 2.0 5.2e-10 38.5 0.2 2.3 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 CBK24359.2 - 3.7e-07 29.6 3.7 0.086 12.9 0.1 7.5 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 CBK24359.2 - 4.4e-05 23.6 6.1 0.57 10.4 0.1 7.1 7 1 0 7 7 7 1 HEAT repeats TPR_19 PF14559.1 CBK24359.2 - 0.017 15.4 2.3 0.91 9.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBK24359.2 - 0.035 13.9 3.2 0.14 12.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.2 CBK24359.2 - 0.037 14.0 0.0 2.4 8.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion TPR_16 PF13432.1 CBK24359.2 - 7.1 7.4 6.6 49 4.7 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.17 CBK24360.2 - 3.2e-54 182.9 0.0 3.6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CBK24360.2 - 0.0073 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Ribosomal_S2 PF00318.15 CBK24361.2 - 1.7e-44 151.5 1.2 6e-22 77.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 TusA PF01206.12 CBK24361.2 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA RRM_1 PF00076.17 CBK24362.2 - 3.2e-36 122.7 0.0 8.9e-17 60.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24362.2 - 9.5e-19 67.1 0.0 1.6e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24362.2 - 5.9e-18 64.4 0.0 7.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBK24362.2 - 0.041 13.6 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 DUF1620 PF07774.8 CBK24362.2 - 0.13 11.4 0.1 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) Coatomer_WDAD PF04053.9 CBK24364.2 - 2.9e-96 322.9 0.0 5e-96 322.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CBK24364.2 - 7.8e-64 215.7 0.0 1.2e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CBK24364.2 - 7e-60 196.9 11.4 3.6e-11 42.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CBK24364.2 - 0.014 13.5 1.2 0.15 10.2 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 zinc_ribbon_5 PF13719.1 CBK24364.2 - 0.036 13.6 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBK24364.2 - 0.041 13.5 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain IKI3 PF04762.7 CBK24364.2 - 0.13 10.0 0.3 4.2 5.0 0.0 2.3 2 0 0 2 2 2 0 IKI3 family zf-ribbon_3 PF13248.1 CBK24364.2 - 0.13 11.4 0.1 0.33 10.2 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ras PF00071.17 CBK24365.2 - 3.4e-49 166.3 0.0 4.2e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK24365.2 - 2.9e-20 72.9 0.0 4.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBK24365.2 - 3.7e-12 45.8 0.0 4.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBK24365.2 - 0.00088 18.7 0.0 0.0022 17.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBK24365.2 - 0.045 13.2 0.1 8.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 CBK24365.2 - 0.082 11.5 0.1 6.6 5.3 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK24365.2 - 0.15 11.1 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region tRNA-synt_2 PF00152.15 CBK24366.2 - 5.5e-87 291.6 0.0 7.2e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBK24366.2 - 5.5e-11 42.1 0.0 1.5e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBK24366.2 - 9.5e-09 34.8 0.2 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) U-box PF04564.10 CBK24368.2 - 0.0024 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.26 CBK24368.2 - 0.0094 15.9 0.0 0.029 14.4 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain CH PF00307.26 CBK24369.2 - 1.3e-09 38.0 0.1 1.6e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DIX PF00778.12 CBK24370.2 - 3.3e-08 33.1 0.1 5.1e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 DIX domain DUF966 PF06136.8 CBK24370.2 - 0.0003 20.3 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) ORC6 PF05460.8 CBK24370.2 - 0.013 14.6 0.7 0.014 14.4 0.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Acatn PF13000.2 CBK24371.2 - 4e-37 127.9 4.0 1.1e-36 126.5 2.8 1.6 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 CBK24371.2 - 1.5e-05 23.8 0.1 1.8e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF805 PF05656.9 CBK24371.2 - 0.18 11.6 3.0 1.5 8.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Ribosomal_L19 PF01245.15 CBK24372.2 - 9e-19 67.3 0.1 1.4e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 TMF_TATA_bd PF12325.3 CBK24373.2 - 9.9e-07 28.5 13.1 9.9e-07 28.5 9.0 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 CBK24373.2 - 0.0034 17.0 8.8 0.0034 17.0 6.1 2.2 2 0 0 2 2 2 1 IncA protein UPF0242 PF06785.6 CBK24373.2 - 0.0092 14.6 6.3 0.014 14.1 4.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) Macoilin PF09726.4 CBK24373.2 - 0.035 12.3 23.5 0.049 11.9 16.3 1.2 1 0 0 1 1 1 0 Transmembrane protein YejG PF13989.1 CBK24373.2 - 0.076 13.0 0.2 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 YejG-like protein DUF4047 PF13256.1 CBK24373.2 - 0.27 11.2 5.2 0.96 9.4 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF1664 PF07889.7 CBK24373.2 - 0.46 10.2 6.7 3 7.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 CBK24373.2 - 2.3 7.3 21.6 0.012 14.8 5.9 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 CBK24373.2 - 2.5 7.7 16.8 0.027 14.1 2.5 2.2 2 0 0 2 2 2 0 Mnd1 family SOBP PF15279.1 CBK24373.2 - 3.8 7.8 8.5 4.5 7.5 5.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein HCMV_UL139 PF12507.3 CBK24373.2 - 4.2 7.5 10.5 0.16 12.1 2.1 2.1 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein CPSF73-100_C PF11718.3 CBK24374.2 - 9.9e-22 77.3 1.8 1.6e-21 76.6 1.2 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CBK24374.2 - 2.2e-21 76.0 0.0 6.9e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 CBK24374.2 - 2.9e-14 52.5 0.0 8.5e-14 51.0 0.0 1.9 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBK24374.2 - 5.3e-12 45.6 0.1 4.6e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK24374.2 - 1.7e-11 44.1 0.2 1.2e-08 34.8 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 CBK24374.2 - 0.0079 15.9 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain KOW PF00467.24 CBK24376.2 - 2.9e-10 39.4 2.4 2.9e-10 39.4 1.7 1.9 2 1 0 2 2 2 1 KOW motif tRNA-synt_2 PF00152.15 CBK24377.2 - 1.7e-91 306.5 0.0 2.2e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBK24377.2 - 2e-11 43.5 0.1 5.5e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CBK24377.2 - 0.00011 21.8 0.1 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CBK24377.2 - 0.021 14.0 0.2 0.38 9.8 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Complex1_51K PF01512.12 CBK24378.2 - 5.2e-43 146.3 0.0 8.2e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CBK24378.2 - 2e-18 65.2 0.8 4.4e-18 64.1 0.5 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CBK24378.2 - 2.7e-07 30.3 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Tubulin PF00091.20 CBK24379.2 - 4.2e-72 242.4 0.1 6.5e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK24379.2 - 2e-43 147.4 0.1 3.2e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBK24379.2 - 6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBK24379.2 - 0.034 13.5 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DUF1681 PF07933.9 CBK24380.2 - 3.4e-39 133.9 0.0 5.8e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) TEX19 PF15553.1 CBK24380.2 - 0.16 11.7 3.7 0.75 9.6 2.3 2.1 2 1 0 2 2 2 0 Testis-expressed protein 19 Utp12 PF04003.7 CBK24381.2 - 2.8e-05 23.9 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family MMR_HSR1 PF01926.18 CBK24382.2 - 9.6e-14 51.3 0.0 1.1e-11 44.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBK24382.2 - 2.1e-05 23.7 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PT PF04886.7 CBK24382.2 - 0.0004 19.6 20.6 0.057 12.7 4.8 2.4 2 0 0 2 2 2 2 PT repeat FeoB_N PF02421.13 CBK24382.2 - 0.002 17.4 0.1 0.0098 15.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CBK24382.2 - 0.034 12.9 0.0 0.08 11.7 0.0 1.6 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 CBK24382.2 - 0.1 12.0 0.2 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2890 PF11081.3 CBK24382.2 - 0.25 11.4 23.8 0.66 10.0 16.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ABC_tran PF00005.22 CBK24382.2 - 0.28 11.4 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter CDC45 PF02724.9 CBK24382.2 - 0.45 8.4 14.3 0.63 8.0 9.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CBK24382.2 - 0.53 7.9 10.9 0.78 7.3 7.5 1.2 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 CBK24382.2 - 2.6 6.3 26.8 5.2 5.4 18.5 1.4 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 CBK24382.2 - 3.8 5.7 31.0 0.029 12.7 16.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Astro_capsid PF03115.9 CBK24382.2 - 4.1 5.5 9.8 14 3.8 7.2 1.5 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Hid1 PF12722.2 CBK24382.2 - 7.4 4.1 10.7 11 3.5 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EF-hand_7 PF13499.1 CBK24383.2 - 1.8e-26 92.0 11.5 8.6e-15 54.6 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBK24383.2 - 2e-22 76.7 22.9 1.7e-06 26.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBK24383.2 - 5.4e-18 64.3 14.2 5e-10 38.8 0.2 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBK24383.2 - 8.8e-15 53.2 13.1 0.00012 21.6 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBK24383.2 - 3.2e-13 48.3 17.5 1.2e-05 24.4 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CBK24383.2 - 2.9e-09 36.7 0.1 0.00041 20.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBK24383.2 - 0.00016 21.6 0.8 0.42 10.6 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBK24383.2 - 0.00045 19.9 5.9 0.47 10.2 0.4 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF2789 PF10982.3 CBK24383.2 - 0.0015 18.5 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2789) EF-hand_10 PF14788.1 CBK24383.2 - 0.011 15.4 8.2 0.037 13.6 0.1 3.8 2 2 1 3 3 3 0 EF hand Glutaredoxin PF00462.19 CBK24383.2 - 0.14 12.1 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin SecE PF00584.15 CBK24384.2 - 4.3e-14 51.8 0.0 5.1e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 CBK24385.2 - 4.5e-60 197.5 18.6 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK24385.2 - 4.3e-05 21.8 8.9 0.0062 14.7 0.1 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK24385.2 - 0.002 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK24385.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK24385.2 - 0.0071 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK24385.2 - 0.011 14.6 0.2 0.45 9.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Gmad1 PF10647.4 CBK24385.2 - 0.067 12.5 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK24385.2 - 0.068 13.4 0.1 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain GAT PF03127.9 CBK24386.2 - 0.091 12.7 1.3 1.8 8.5 0.3 2.6 2 1 0 2 2 2 0 GAT domain FUSC PF04632.7 CBK24386.2 - 0.15 10.4 7.6 0.039 12.4 2.5 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Syja_N PF02383.13 CBK24387.2 - 5.4e-64 215.9 0.0 1.1e-63 215.0 0.0 1.5 1 1 0 1 1 1 1 SacI homology domain HEAT PF02985.17 CBK24388.2 - 1.3e-25 87.1 3.9 2.9e-06 26.9 0.0 5.8 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 CBK24388.2 - 1e-12 48.1 0.3 2.2e-07 31.0 0.0 3.4 2 1 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.2 CBK24388.2 - 1.4e-07 31.8 1.0 0.007 16.7 0.0 4.2 2 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CBK24388.2 - 4.1e-07 28.7 5.6 7.2e-06 24.6 0.6 2.1 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 CBK24388.2 - 1.7e-06 28.3 0.6 0.01 16.3 0.0 5.0 3 1 2 5 5 5 1 HEAT-like repeat CLASP_N PF12348.3 CBK24388.2 - 5.8e-06 25.8 0.3 0.005 16.2 0.1 2.9 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 CBK24388.2 - 0.0013 18.4 0.2 0.15 11.8 0.0 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CBK24388.2 - 0.0013 18.6 1.6 0.84 9.4 0.1 2.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.6 CBK24388.2 - 0.0022 17.5 0.1 0.18 11.2 0.0 3.0 2 2 0 2 2 2 1 DNA alkylation repair enzyme DUF1546 PF07571.8 CBK24388.2 - 0.019 15.0 0.1 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1546) DIM1 PF02966.11 CBK24389.2 - 3e-62 207.9 0.7 3.4e-62 207.8 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CBK24389.2 - 0.01 15.5 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RhaT PF06379.7 CBK24389.2 - 0.052 12.5 0.0 0.06 12.3 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) GidB PF02527.10 CBK24389.2 - 0.081 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Thioredoxin_7 PF13899.1 CBK24389.2 - 0.14 12.1 0.1 0.28 11.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like GTP_EFTU PF00009.22 CBK24390.2 - 7.5e-37 126.5 0.0 1.3e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CBK24390.2 - 4.5e-36 122.7 0.4 9.8e-36 121.6 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CBK24390.2 - 9.7e-11 41.6 1.5 2.4e-10 40.3 1.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK24390.2 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBK24390.2 - 0.07 12.9 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Dynamin family E3_binding PF02817.12 CBK24391.2 - 9.2e-10 38.0 0.0 2.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.18 CBK24391.2 - 1.2e-05 24.7 3.4 0.00016 20.9 2.3 2.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF612 PF04747.7 CBK24391.2 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF612 DUF2763 PF10961.3 CBK24393.2 - 0.002 18.5 1.4 0.0042 17.4 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) Nucleotid_trans PF03407.11 CBK24393.2 - 0.093 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase HEAT_2 PF13646.1 CBK24394.2 - 1e-05 25.7 0.1 0.0087 16.3 0.0 3.3 2 1 2 4 4 3 1 HEAT repeats HEAT PF02985.17 CBK24394.2 - 0.052 13.6 0.7 1.4 9.1 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 CBK24394.2 - 0.56 10.7 5.5 14 6.3 0.0 4.7 3 1 1 4 4 4 0 HEAT-like repeat GATase_5 PF13507.1 CBK24395.2 - 1.9e-96 321.9 0.0 2.9e-96 321.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CBK24395.2 - 2e-24 86.3 0.2 2.8e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CBK24395.2 - 4.4e-13 49.2 0.1 1.1e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain HIT PF01230.18 CBK24396.2 - 3.1e-23 82.1 0.2 3.6e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBK24396.2 - 1.6e-20 73.4 0.0 1.9e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3165 PF11364.3 CBK24396.2 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) TRAP_beta PF05753.9 CBK24397.2 - 1.5e-13 50.3 0.0 1.8e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) SMC_N PF02463.14 CBK24398.2 - 4e-29 101.4 5.3 8.5e-29 100.3 3.7 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK24398.2 - 3.1e-06 27.3 11.1 0.00069 19.6 0.1 3.1 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBK24398.2 - 8.5e-06 26.2 40.1 8.5e-06 26.2 27.8 5.8 3 2 1 4 4 2 1 AAA domain AAA_29 PF13555.1 CBK24398.2 - 7.1e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBK24398.2 - 0.0055 16.5 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CBK24398.2 - 0.024 14.7 2.0 1.9 8.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CBK24398.2 - 0.052 12.9 1.3 2.9 7.2 0.0 3.5 3 1 0 3 3 3 0 AAA domain Reo_sigmaC PF04582.7 CBK24398.2 - 0.075 12.2 23.7 0.22 10.6 2.3 4.1 3 1 1 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CBK24398.2 - 0.43 10.8 0.0 0.43 10.8 0.0 6.3 3 2 0 3 3 1 0 ABC transporter AAA_13 PF13166.1 CBK24398.2 - 5.6 5.3 89.0 0.16 10.4 16.5 5.4 2 2 3 5 5 5 0 AAA domain NPV_P10 PF05531.7 CBK24398.2 - 6.1 7.1 33.3 0.11 12.7 0.6 7.5 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein Carboxyl_trans PF01039.17 CBK24399.2 - 1e-190 634.3 0.1 1.2e-190 634.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK24399.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) PPDK_N PF01326.14 CBK24400.2 - 1.3e-60 205.1 0.0 2.1e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 CBK24400.2 - 4.7e-20 70.9 0.2 1e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain CaM_binding PF07839.6 CBK24400.2 - 0.89 9.7 3.3 3.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Plant calmodulin-binding domain Endomucin PF07010.7 CBK24401.2 - 0.00018 20.9 1.0 0.00025 20.4 0.1 1.7 2 0 0 2 2 2 1 Endomucin He_PIG PF05345.7 CBK24401.2 - 0.0026 17.7 0.0 0.0086 16.0 0.0 1.9 1 0 0 1 1 1 1 Putative Ig domain P12 PF12669.2 CBK24401.2 - 0.0036 17.4 0.6 0.0082 16.3 0.4 1.6 1 0 0 1 1 1 1 Virus attachment protein p12 family Sushi PF00084.15 CBK24401.2 - 0.0047 17.2 3.3 0.012 15.8 0.4 2.5 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SecG PF03840.9 CBK24401.2 - 0.0092 15.6 1.3 0.018 14.7 0.9 1.5 1 0 0 1 1 1 1 Preprotein translocase SecG subunit HSP90 PF00183.13 CBK24402.2 - 2.6e-182 606.9 59.9 2.6e-182 606.9 41.5 2.7 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.21 CBK24402.2 - 7e-10 38.6 0.2 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBK24402.2 - 2e-09 37.1 0.1 2e-09 37.1 0.1 3.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.5 CBK24402.2 - 0.01 14.3 4.9 0.022 13.2 1.8 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup BRO1 PF03097.13 CBK24403.2 - 5.2e-27 94.5 2.0 8.3e-27 93.9 0.4 2.0 1 1 1 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CBK24403.2 - 2.5e-20 72.6 17.8 2e-19 69.6 11.1 2.8 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV PspA_IM30 PF04012.7 CBK24403.2 - 1.5 8.0 13.9 0.36 10.1 5.5 2.9 2 1 1 3 3 3 0 PspA/IM30 family FlaC_arch PF05377.6 CBK24403.2 - 1.7 8.5 4.4 16 5.4 0.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CLU PF13236.1 CBK24404.2 - 9.8e-15 54.5 0.0 2.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria CLU_N PF15044.1 CBK24404.2 - 5.2e-14 52.1 0.2 1.3e-13 50.8 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.7 CBK24404.2 - 1.4e-07 31.3 0.1 3.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Flagellin_IN PF07196.8 CBK24404.2 - 0.067 13.1 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif 6PGD PF00393.14 CBK24405.2 - 2.2e-114 381.5 0.0 2.8e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBK24405.2 - 2.6e-42 144.4 0.0 4e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBK24405.2 - 0.051 13.6 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 CBK24405.2 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF563 PF04577.9 CBK24406.2 - 2.7e-14 53.5 0.6 3.7e-14 53.1 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF563) CofC PF01983.11 CBK24406.2 - 0.033 13.1 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Rod_cone_degen PF15201.1 CBK24406.2 - 0.073 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration RAP1 PF07218.6 CBK24408.2 - 0.19 9.8 8.3 0.22 9.5 5.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1777 PF08648.7 CBK24408.2 - 0.41 10.3 56.7 0.59 9.8 39.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Transformer PF06495.6 CBK24408.2 - 2.7 7.8 51.5 0.88 9.4 28.9 2.3 1 1 1 2 2 2 0 Fruit fly transformer protein UPF0004 PF00919.15 CBK24410.2 - 9.4e-17 60.6 0.0 1.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 CBK24410.2 - 4.5e-16 59.4 0.0 7.3e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.15 CBK24410.2 - 0.00041 20.0 0.1 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 TRAM domain Polysacc_deac_2 PF04748.8 CBK24410.2 - 0.068 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF1450 PF07293.6 CBK24410.2 - 0.11 12.5 0.0 0.44 10.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) AAA PF00004.24 CBK24412.2 - 7e-16 58.6 0.0 7.4e-12 45.6 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBK24412.2 - 2.9e-06 27.4 0.0 0.0005 20.1 0.0 2.8 1 1 1 2 2 2 1 RNA helicase AAA_18 PF13238.1 CBK24412.2 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK24412.2 - 0.00022 20.2 0.0 0.00051 19.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 CBK24412.2 - 0.0003 21.5 0.0 0.001 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBK24412.2 - 0.00048 19.6 0.0 0.00093 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 CBK24412.2 - 0.00051 19.7 0.0 0.028 14.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CBK24412.2 - 0.00075 19.2 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UFD1 PF03152.9 CBK24412.2 - 0.0051 15.9 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 DUF3760 PF12586.3 CBK24412.2 - 0.0076 16.0 0.0 4 7.3 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3760) Miro PF08477.8 CBK24412.2 - 0.011 16.2 0.4 0.05 14.1 0.0 2.5 3 1 0 3 3 1 0 Miro-like protein AAA_29 PF13555.1 CBK24412.2 - 0.012 15.1 0.4 0.36 10.3 0.3 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CBK24412.2 - 0.012 15.7 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBK24412.2 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 CBK24412.2 - 0.014 14.0 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CBK24412.2 - 0.016 15.1 0.7 0.24 11.3 0.0 3.0 2 1 2 4 4 4 0 AAA ATPase domain AAA_14 PF13173.1 CBK24412.2 - 0.035 13.9 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBK24412.2 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBK24412.2 - 0.048 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBK24412.2 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CBK24412.2 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CBK24412.2 - 0.067 12.6 0.1 0.26 10.6 0.0 2.0 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 CBK24412.2 - 0.072 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 CBK24412.2 - 0.081 12.3 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CBK24412.2 - 4.8 7.4 6.2 1.3 9.3 1.6 1.9 2 1 0 2 2 1 0 AAA domain YTH PF04146.10 CBK24413.2 - 0.099 12.2 0.1 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 YT521-B-like domain Glyco_transf_49 PF13896.1 CBK24414.2 - 1.5e-09 37.3 3.6 8e-08 31.7 0.5 2.5 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK24414.2 - 0.00089 18.9 0.8 0.0029 17.3 0.4 2.0 1 1 1 2 2 2 2 F-box associated Ku_PK_bind PF08785.6 CBK24415.2 - 0.037 13.9 0.3 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Ku C terminal domain like RNase_P_pop3 PF08228.6 CBK24415.2 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.21 CBK24417.2 - 1.3e-21 75.9 0.6 2.1e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK24417.2 - 0.042 13.6 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 MoeZ_MoeB PF05237.8 CBK24418.2 - 0.1 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 MoeZ/MoeB domain Glyco_transf_49 PF13896.1 CBK24419.2 - 2.5e-19 69.5 5.6 1.9e-15 56.8 1.9 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK24419.2 - 0.0015 17.6 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PHD PF00628.24 CBK24421.2 - 3.5e-06 26.6 12.7 6.1e-06 25.8 8.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK24421.2 - 0.063 12.6 9.1 0.13 11.6 6.3 1.6 1 0 0 1 1 1 0 PHD-finger Collagen PF01391.13 CBK24421.2 - 0.2 11.2 7.6 0.4 10.2 5.3 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF1517 PF07466.6 CBK24421.2 - 0.68 8.8 4.0 1.6 7.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1423 PF07227.6 CBK24421.2 - 5.1 5.6 7.0 12 4.4 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) C1_1 PF00130.17 CBK24421.2 - 9.1 6.0 10.6 1.3 8.8 4.3 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CBK24422.2 - 7.1e-08 32.0 11.8 9.4e-08 31.6 8.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CBK24422.2 - 0.0054 16.0 7.4 0.0054 16.0 5.1 2.2 1 1 1 2 2 2 1 PHD-finger PHF5 PF03660.9 CBK24422.2 - 0.024 14.7 4.4 0.026 14.5 3.1 1.1 1 0 0 1 1 1 0 PHF5-like protein DUF4428 PF14471.1 CBK24422.2 - 0.082 12.6 0.0 0.082 12.6 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DZR PF12773.2 CBK24422.2 - 0.22 11.3 10.5 1.8 8.4 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 CBK24422.2 - 0.23 11.2 12.2 0.077 12.7 5.0 2.0 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.1 CBK24422.2 - 3.8 7.9 8.8 16 5.9 6.1 1.8 1 1 0 1 1 1 0 Cytochrome c3 Zn-ribbon_8 PF09723.5 CBK24422.2 - 7.2 6.6 10.9 6.1 6.8 0.2 2.7 2 1 0 2 2 2 0 Zinc ribbon domain Glyco_hydro_47 PF01532.15 CBK24423.2 - 1e-99 334.2 0.1 1.2e-99 334.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_fac_C PF08542.6 CBK24424.2 - 1.7e-18 66.3 0.0 3.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBK24424.2 - 3.5e-13 49.5 0.1 4.4e-11 42.7 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBK24424.2 - 1.7e-12 47.7 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBK24424.2 - 2.1e-09 36.6 0.1 9.1e-06 24.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CBK24424.2 - 3.1e-07 29.6 0.0 6.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK24424.2 - 5.9e-06 26.4 0.1 0.00076 19.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBK24424.2 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBK24424.2 - 4.4e-05 22.7 0.2 0.00035 19.8 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBK24424.2 - 5.9e-05 23.1 0.0 0.0015 18.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 CBK24424.2 - 7.5e-05 22.3 0.0 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CBK24424.2 - 8.6e-05 22.1 0.0 0.0046 16.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_5 PF07728.9 CBK24424.2 - 9.1e-05 22.2 0.2 0.00059 19.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBK24424.2 - 0.00018 21.1 0.1 0.00044 19.9 0.1 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBK24424.2 - 0.00057 19.3 0.3 0.001 18.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBK24424.2 - 0.0025 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBK24424.2 - 0.0046 16.5 0.2 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBK24424.2 - 0.0081 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 CBK24424.2 - 0.01 14.6 0.3 0.026 13.3 0.1 1.7 2 1 0 2 2 2 1 ArgK protein SRP54 PF00448.17 CBK24424.2 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 CBK24424.2 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBK24424.2 - 0.019 14.4 0.4 0.078 12.3 0.3 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CBK24424.2 - 0.021 13.5 0.1 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus CbiA PF01656.18 CBK24424.2 - 0.031 13.6 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.24 CBK24424.2 - 0.038 13.4 0.2 6.2 6.2 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase DUF3804 PF12707.2 CBK24424.2 - 0.046 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) RNA_helicase PF00910.17 CBK24424.2 - 0.046 13.8 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase MipZ PF09140.6 CBK24424.2 - 0.053 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 CBK24424.2 - 0.055 13.7 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBK24424.2 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBK24424.2 - 0.085 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 CBK24424.2 - 0.092 12.4 0.2 1 9.0 0.1 2.2 1 1 1 2 2 2 0 NTPase PhoH PF02562.11 CBK24424.2 - 0.11 11.6 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Integrase_Zn PF02022.14 CBK24424.2 - 0.19 11.2 2.3 0.38 10.2 1.6 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain BPL_N PF09825.4 CBK24425.2 - 1.1e-40 139.6 0.0 1.3e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase PF00117.23 CBK24425.2 - 0.00077 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CBK24425.2 - 0.0032 17.0 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain IKI3 PF04762.7 CBK24426.2 - 2.5e-28 98.4 0.1 3.8e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 IKI3 family Herpes_U34 PF04541.8 CBK24426.2 - 0.025 13.4 0.5 9.9 5.0 0.0 3.0 2 1 1 3 3 3 0 Herpesvirus virion protein U34 TPR_2 PF07719.12 CBK24426.2 - 0.081 12.8 1.3 0.38 10.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.15 CBK24427.2 - 5.8e-29 100.4 0.1 6.9e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24427.2 - 1.4e-09 37.0 0.1 1.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBK24427.2 - 0.014 14.3 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 StbA protein MutL PF13941.1 CBK24427.2 - 0.017 13.4 0.1 0.025 12.9 0.1 1.2 1 0 0 1 1 1 0 MutL protein Hydantoinase_A PF01968.13 CBK24427.2 - 0.033 13.2 0.1 0.066 12.3 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Hexokinase_1 PF00349.16 CBK24427.2 - 0.049 12.9 0.0 2.3 7.5 0.0 3.0 3 1 0 3 3 3 0 Hexokinase Methyltransf_8 PF05148.10 CBK24427.2 - 0.1 12.1 0.0 11 5.5 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF4379 PF14311.1 CBK24428.2 - 3.5e-34 116.3 16.1 8.5e-18 63.9 1.5 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4379) PhageMin_Tail PF10145.4 CBK24429.2 - 0.14 11.7 16.4 0.23 11.0 11.3 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein DUF4225 PF13988.1 CBK24429.2 - 8.3 5.8 8.7 14 5.0 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Methyltransf_11 PF08241.7 CBK24430.2 - 3.2e-15 56.3 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK24430.2 - 1.5e-12 47.3 0.2 1.6e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK24430.2 - 4.4e-08 33.5 0.1 5.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK24430.2 - 9.9e-08 32.5 0.0 1.4e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBK24430.2 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK24430.2 - 0.0013 19.0 0.0 0.0032 17.7 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBK24430.2 - 0.0054 15.8 0.1 0.0068 15.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CBK24430.2 - 0.014 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 CBK24430.2 - 0.024 13.8 0.3 0.033 13.3 0.2 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 CBK24430.2 - 0.041 13.5 0.3 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase NodS PF05401.6 CBK24430.2 - 0.063 12.6 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) E1-E2_ATPase PF00122.15 CBK24431.2 - 6.3e-11 41.7 0.2 1e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase V-ATPase_G PF03179.10 CBK24432.2 - 5.6e-25 87.6 14.3 6.7e-25 87.4 9.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.13 CBK24432.2 - 0.00047 19.5 11.9 0.00059 19.1 8.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3552 PF12072.3 CBK24432.2 - 0.0023 17.1 14.6 0.0023 17.1 10.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) MCD PF05292.6 CBK24432.2 - 0.025 13.3 0.1 0.031 12.9 0.1 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) Rootletin PF15035.1 CBK24432.2 - 0.029 14.3 6.7 0.034 14.1 4.6 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RRF PF01765.14 CBK24432.2 - 0.046 13.1 6.6 0.06 12.8 4.6 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF3450 PF11932.3 CBK24432.2 - 0.052 12.8 8.5 0.058 12.6 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATP-synt_B PF00430.13 CBK24432.2 - 0.055 13.2 20.3 0.19 11.5 13.4 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DDRGK PF09756.4 CBK24432.2 - 0.12 11.7 13.6 0.16 11.3 9.4 1.1 1 0 0 1 1 1 0 DDRGK domain AIF-MLS PF14962.1 CBK24432.2 - 0.66 9.6 9.9 0.78 9.3 6.9 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence PEPcase_2 PF14010.1 CBK24432.2 - 0.71 8.1 6.2 0.14 10.3 0.4 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase Herpes_UL36 PF03586.8 CBK24432.2 - 1 8.3 7.0 1.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein CPSF73-100_C PF11718.3 CBK24432.2 - 1.4 8.2 6.7 1.7 7.9 4.7 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Kinetocho_Slk19 PF12709.2 CBK24432.2 - 2 8.5 10.8 11 6.2 2.9 2.8 1 1 2 3 3 3 0 Central kinetochore-associated Casc1 PF12366.3 CBK24432.2 - 2.3 7.6 9.1 6.4 6.2 6.3 1.7 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 Fib_alpha PF08702.5 CBK24432.2 - 2.3 8.3 6.2 4.1 7.5 4.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HrpE PF06188.7 CBK24432.2 - 2.9 7.5 10.4 3.9 7.1 7.0 1.3 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E HSP70 PF00012.15 CBK24432.2 - 3.7 5.3 11.8 4.3 5.1 8.2 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF883 PF05957.8 CBK24432.2 - 4.9 7.6 9.4 8.9 6.7 6.3 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Vfa1 PF08432.5 CBK24432.2 - 6 6.8 13.0 7.6 6.5 9.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FlgN PF05130.7 CBK24432.2 - 6.5 7.0 11.3 9.7 6.4 7.9 1.3 1 1 0 1 1 1 0 FlgN protein DUF4230 PF14014.1 CBK24432.2 - 6.5 6.5 9.4 6.5 6.5 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) DRY_EERY PF09750.4 CBK24432.2 - 6.9 6.8 9.8 32 4.6 0.2 2.1 1 1 1 2 2 2 0 Alternative splicing regulator Muted PF14942.1 CBK24432.2 - 9.9 6.0 12.4 19 5.1 8.1 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Stanniocalcin PF03298.8 CBK24433.2 - 0.077 12.0 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Stanniocalcin family PRP38_assoc PF12871.2 CBK24433.2 - 0.48 10.9 81.4 0.07 13.6 33.4 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIP-T3 PF10243.4 CBK24433.2 - 1.7 7.0 27.7 2.2 6.6 19.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nucleo_P87 PF07267.6 CBK24433.2 - 2.3 6.7 21.0 2.9 6.4 14.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1777 PF08648.7 CBK24433.2 - 6.6 6.4 66.8 6.4 6.4 45.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) ORC6 PF05460.8 CBK24433.2 - 6.8 5.6 20.1 8.3 5.3 14.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SH3_1 PF00018.23 CBK24434.2 - 5.8e-16 57.6 0.1 6.7e-16 57.4 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CBK24434.2 - 1.8e-13 49.7 0.1 2.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBK24434.2 - 5.4e-09 35.4 0.1 6.3e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain FtsJ PF01728.14 CBK24435.2 - 2.3e-65 219.9 0.3 2.8e-65 219.6 0.2 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CBK24435.2 - 0.12 12.9 0.0 0.42 11.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain SGT1 PF07093.6 CBK24436.2 - 0.021 13.2 15.9 0.025 12.9 11.0 1.0 1 0 0 1 1 1 0 SGT1 protein TFIIF_alpha PF05793.7 CBK24436.2 - 0.021 13.2 25.2 0.025 12.9 17.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 CBK24436.2 - 0.053 12.7 28.5 0.061 12.5 19.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CBK24436.2 - 2.6 5.8 29.8 3.4 5.4 20.7 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 CBK24436.2 - 3 6.8 30.0 4 6.3 20.8 1.2 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 CBK24436.2 - 4.8 6.4 11.2 6.5 6.0 7.8 1.2 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 CBK24436.2 - 6.1 4.3 9.7 6.4 4.3 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sin3_corepress PF08295.7 CBK24437.2 - 1.9e-29 101.3 0.1 4.1e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor TFIIE-A_C-term PF11521.3 CBK24437.2 - 0.83 9.6 0.0 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ribosomal_60s PF00428.14 CBK24437.2 - 5.7 7.4 12.2 1.7 9.0 6.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HSP70 PF00012.15 CBK24438.2 - 1.1e-258 859.1 8.9 3.2e-258 857.6 6.2 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24438.2 - 4.7e-15 55.0 0.2 8.4e-14 50.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBK24438.2 - 0.0051 16.6 0.7 0.063 13.1 0.0 3.0 2 2 0 2 2 2 1 Cell division protein FtsA DDR PF08841.5 CBK24438.2 - 0.008 15.0 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBK24438.2 - 0.0084 15.2 0.1 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase WD40 PF00400.27 CBK24439.2 - 3.6e-43 143.9 26.7 4.8e-09 35.7 0.4 9.1 10 0 0 10 10 10 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBK24439.2 - 0.00016 20.5 0.1 1.1 7.9 0.0 3.5 3 1 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 CBK24439.2 - 0.067 11.3 0.1 0.18 9.8 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Bromodomain PF00439.20 CBK24440.2 - 4.6e-30 103.3 12.7 1.2e-15 57.1 0.2 6.0 5 1 0 5 5 5 4 Bromodomain STAG PF08514.6 CBK24440.2 - 0.17 11.6 4.3 0.15 11.7 0.5 2.8 4 0 0 4 4 4 0 STAG domain Peptidase_M20 PF01546.23 CBK24441.2 - 5.2e-19 68.4 0.0 1.4e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CBK24441.2 - 0.0085 14.8 0.0 0.058 12.1 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase M20_dimer PF07687.9 CBK24441.2 - 0.036 13.7 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain HOOK PF05622.7 CBK24442.2 - 4.4e-09 34.7 0.6 4.4e-09 34.7 0.4 5.5 3 2 2 5 5 5 3 HOOK protein ATG16 PF08614.6 CBK24442.2 - 0.00013 21.8 68.0 0.023 14.5 9.8 4.4 2 1 1 4 4 4 3 Autophagy protein 16 (ATG16) CH PF00307.26 CBK24442.2 - 0.0019 18.2 0.0 0.0097 15.9 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LPP PF04728.8 CBK24442.2 - 0.0047 16.6 0.2 0.0047 16.6 0.2 4.0 4 0 0 4 4 4 1 Lipoprotein leucine-zipper APG6 PF04111.7 CBK24442.2 - 0.083 11.9 72.7 0.01 14.9 12.7 4.6 2 2 2 4 4 4 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CBK24442.2 - 5.5 6.8 75.6 0.017 14.8 7.9 7.9 4 1 5 9 9 9 0 TATA element modulatory factor 1 DNA binding Seadorna_VP6 PF07407.6 CBK24442.2 - 5.9 5.5 11.1 0.26 10.0 3.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF3584 PF12128.3 CBK24442.2 - 7.1 3.8 57.4 0.23 8.7 22.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ATG27 PF09451.5 CBK24443.2 - 5.7e-05 22.4 0.0 0.00021 20.6 0.0 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 CBK24443.2 - 0.00069 19.3 0.7 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat WAK_assoc PF14380.1 CBK24443.2 - 0.44 11.0 7.5 1.2 9.7 4.2 2.4 2 1 0 2 2 2 0 Wall-associated receptor kinase C-terminal EGF_2 PF07974.8 CBK24443.2 - 1.2 9.3 18.4 0.12 12.5 8.8 2.4 2 0 0 2 2 2 0 EGF-like domain Pkinase PF00069.20 CBK24444.2 - 4.1e-65 219.5 0.0 5.6e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24444.2 - 4.5e-42 143.9 0.0 7.8e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24444.2 - 5.9e-07 28.7 0.0 2.1e-05 23.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like PBD PF00786.23 CBK24444.2 - 2.6e-06 27.7 0.0 1.4e-05 25.3 0.0 2.2 3 0 0 3 3 3 1 P21-Rho-binding domain APH PF01636.18 CBK24444.2 - 0.061 13.0 0.1 5.4 6.6 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBK24444.2 - 0.13 11.0 0.1 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PWI PF01480.12 CBK24445.2 - 0.0033 17.4 0.5 0.0083 16.2 0.1 1.9 2 0 0 2 2 2 1 PWI domain PRKCSH_1 PF13015.1 CBK24445.2 - 0.24 10.8 3.1 8.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Asp-B-Hydro_N PF05279.6 CBK24445.2 - 3.4 7.4 18.4 5.3 6.8 12.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ENTH PF01417.15 CBK24446.2 - 6e-24 84.2 0.1 1.1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 ENTH domain AAT PF03417.11 CBK24446.2 - 1.1e-19 70.8 0.0 1.1e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase eIF-3_zeta PF05091.7 CBK24446.2 - 5.7 5.4 16.4 10 4.6 11.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Symplekin_C PF12295.3 CBK24447.2 - 0.059 13.2 1.0 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal MutS_III PF05192.13 CBK24447.2 - 0.21 11.3 3.1 0.45 10.2 2.1 1.7 1 1 0 1 1 1 0 MutS domain III Proteasome PF00227.21 CBK24448.2 - 8.8e-43 145.8 0.1 1.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 CBK24449.2 - 1.2e-24 86.8 0.0 2.8e-24 85.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24449.2 - 9e-20 70.8 0.0 2.3e-19 69.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBK24449.2 - 0.00087 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CBK24450.2 - 0.002 17.3 0.5 0.0024 17.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain DUF4094 PF13334.1 CBK24450.2 - 0.012 15.9 0.4 0.014 15.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Med9 PF07544.8 CBK24450.2 - 0.046 13.4 3.5 0.086 12.5 2.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.4 CBK24450.2 - 0.054 12.4 0.5 0.058 12.3 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med4 PF10018.4 CBK24450.2 - 0.057 12.8 1.3 0.085 12.2 0.9 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4200 PF13863.1 CBK24450.2 - 0.067 13.1 6.7 0.089 12.7 3.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 CBK24450.2 - 0.097 12.2 1.0 0.13 11.8 0.5 1.3 1 1 0 1 1 1 0 IncA protein Osmo_CC PF08946.5 CBK24450.2 - 0.11 12.5 3.6 0.28 11.2 1.4 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil RbsD_FucU PF05025.8 CBK24450.2 - 0.13 12.6 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 RbsD / FucU transport protein family CCDC-167 PF15188.1 CBK24450.2 - 0.6 10.0 3.7 2.9 7.8 1.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ribosomal_S8e PF01201.17 CBK24451.2 - 6.5e-35 120.1 0.1 7.7e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Rifin_STEVOR PF02009.11 CBK24452.2 - 0.00014 21.6 0.3 0.00022 21.0 0.2 1.3 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 CBK24452.2 - 0.0079 16.5 0.5 0.018 15.4 0.4 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 CBK24452.2 - 0.017 13.4 0.2 0.026 12.7 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.9 CBK24452.2 - 0.023 14.4 2.6 0.053 13.2 1.8 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF912 PF06024.7 CBK24452.2 - 0.038 14.0 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 CBK24452.2 - 0.041 13.5 0.1 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SP_C-Propep PF08999.5 CBK24452.2 - 0.044 13.2 1.8 0.096 12.1 1.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF4448 PF14610.1 CBK24452.2 - 0.062 12.7 0.4 0.095 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FixQ PF05545.6 CBK24452.2 - 0.073 12.7 1.0 0.18 11.4 0.7 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF3302 PF11742.3 CBK24452.2 - 0.099 12.5 3.6 0.19 11.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Syndecan PF01034.15 CBK24452.2 - 0.11 12.1 1.3 0.22 11.2 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4245 PF14030.1 CBK24452.2 - 0.19 11.4 1.1 0.34 10.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Ribosomal_S13_N PF08069.7 CBK24453.2 - 1.8e-28 98.1 1.9 2.9e-28 97.4 0.1 2.1 3 0 0 3 3 3 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBK24453.2 - 6.4e-23 80.3 0.2 1e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Pkinase PF00069.20 CBK24454.2 - 3.6e-68 229.5 0.0 4.2e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24454.2 - 1.8e-37 128.8 0.0 2.1e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24454.2 - 4.2e-05 22.6 0.0 7.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK24454.2 - 0.011 14.7 0.0 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBK24454.2 - 0.031 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBK24454.2 - 0.073 11.8 0.1 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 AAA_2 PF07724.9 CBK24456.2 - 2.5e-54 183.7 0.0 2.5e-52 177.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBK24456.2 - 2e-26 92.7 0.8 1.4e-15 57.6 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBK24456.2 - 3.8e-22 77.9 1.6 2.2e-21 75.5 0.1 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBK24456.2 - 4.2e-16 58.9 1.6 9.4e-11 41.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CBK24456.2 - 6e-15 54.9 2.9 3.3e-07 30.1 0.0 4.2 5 0 0 5 5 4 2 Clp amino terminal domain AAA_16 PF13191.1 CBK24456.2 - 5.5e-14 52.5 4.3 6.3e-05 23.0 0.0 4.8 3 2 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 CBK24456.2 - 1.3e-12 47.9 1.6 0.00016 21.8 0.0 4.7 4 2 0 4 4 4 2 AAA domain AAA_14 PF13173.1 CBK24456.2 - 2.3e-09 37.2 0.0 0.0009 19.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CBK24456.2 - 1.6e-08 34.2 0.0 0.0056 16.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBK24456.2 - 6.3e-07 29.0 0.0 0.00016 21.2 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CBK24456.2 - 5.2e-06 27.2 10.3 0.0014 19.4 0.0 4.3 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 CBK24456.2 - 1.6e-05 24.6 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.7 CBK24456.2 - 1.6e-05 24.0 0.0 0.0013 17.8 0.0 3.2 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 CBK24456.2 - 3.5e-05 24.1 13.9 0.026 14.8 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 CBK24456.2 - 3.5e-05 23.4 0.0 0.17 11.6 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 CBK24456.2 - 4e-05 23.1 0.0 0.19 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CBK24456.2 - 5.9e-05 23.1 0.1 0.31 11.2 0.0 3.5 4 0 0 4 4 2 1 RNA helicase DUF815 PF05673.8 CBK24456.2 - 0.00016 20.6 0.1 0.016 14.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBK24456.2 - 0.00031 19.8 2.8 0.094 11.7 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 CBK24456.2 - 0.0007 19.3 0.0 0.34 10.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CBK24456.2 - 0.0013 17.7 0.0 0.0078 15.1 0.0 2.2 2 1 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 CBK24456.2 - 0.0013 17.9 0.0 1.8 7.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 CBK24456.2 - 0.002 17.3 0.0 1.7 7.7 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBK24456.2 - 0.0025 17.7 5.6 0.55 10.1 0.0 3.9 4 1 0 4 4 3 1 AAA domain AAA_3 PF07726.6 CBK24456.2 - 0.0028 17.2 0.0 3 7.4 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBK24456.2 - 0.003 17.2 17.7 0.077 12.6 0.5 5.2 4 3 0 4 4 2 2 Archaeal ATPase ResIII PF04851.10 CBK24456.2 - 0.0036 17.1 0.2 0.54 10.0 0.0 3.8 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CBK24456.2 - 0.0043 16.9 0.0 1.3 8.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.1 CBK24456.2 - 0.0056 16.3 0.1 0.097 12.3 0.0 3.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit MMR_HSR1 PF01926.18 CBK24456.2 - 0.0079 16.1 0.0 0.98 9.3 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBK24456.2 - 0.013 15.2 0.1 4.8 6.8 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.1 CBK24456.2 - 0.017 14.6 0.0 2.6 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.7 CBK24456.2 - 0.026 14.2 6.5 0.1 12.3 4.5 2.1 1 0 0 1 1 1 0 Laminin Domain II AAA_10 PF12846.2 CBK24456.2 - 0.032 13.6 8.1 0.21 11.0 0.1 4.4 3 2 0 4 4 4 0 AAA-like domain UPF0079 PF02367.12 CBK24456.2 - 0.037 13.6 0.0 6.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CBK24456.2 - 0.058 12.9 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 CBK24456.2 - 0.058 13.8 1.9 2.9 8.4 0.0 3.7 4 1 0 4 4 3 0 Miro-like protein AAA_23 PF13476.1 CBK24456.2 - 0.081 13.2 0.0 0.081 13.2 0.0 5.0 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.17 CBK24456.2 - 0.095 12.1 8.7 0.28 10.5 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 CBK24456.2 - 0.23 11.2 9.1 0.5 10.1 0.0 3.7 4 0 0 4 4 3 0 Domain of unknown function DUF87 Ank_5 PF13857.1 CBK24457.2 - 1.2e-10 41.2 0.4 1.8e-09 37.5 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBK24457.2 - 3.4e-10 39.2 0.9 3.8e-08 32.7 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBK24457.2 - 4.7e-10 39.7 0.3 2.6e-09 37.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBK24457.2 - 1.7e-09 37.8 0.1 2.8e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBK24457.2 - 3.1e-08 33.0 0.1 9.8e-06 25.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat TatD_DNase PF01026.16 CBK24458.2 - 2.7e-46 157.8 0.0 3.1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Actin PF00022.14 CBK24459.2 - 4.3e-89 298.6 0.0 8e-89 297.7 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK24459.2 - 0.0016 17.0 0.0 0.26 9.8 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein LRR_5 PF13306.1 CBK24460.2 - 9.6e-25 86.7 146.6 1.3e-07 31.3 4.9 12.9 4 3 7 12 12 12 10 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CBK24460.2 - 4.6e-19 67.9 128.0 2.3e-05 24.0 2.5 24.4 12 6 16 29 29 29 19 Leucine rich repeat He_PIG PF05345.7 CBK24463.2 - 1.1e-21 76.5 37.5 1e-05 25.4 0.8 6.7 6 0 0 6 6 6 5 Putative Ig domain I-set PF07679.11 CBK24463.2 - 0.00034 20.3 5.0 4 7.3 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF2627 PF11118.3 CBK24463.2 - 0.32 11.1 0.6 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) IncA PF04156.9 CBK24463.2 - 0.38 10.3 0.1 0.57 9.7 0.1 1.2 1 0 0 1 1 1 0 IncA protein HRM PF02793.17 CBK24463.2 - 1.3 9.1 11.0 11 6.0 0.0 4.9 5 0 0 5 5 5 0 Hormone receptor domain DUF3185 PF11381.3 CBK24463.2 - 3.3 7.5 7.9 11 5.9 5.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) hEGF PF12661.2 CBK24463.2 - 4.6 7.5 7.3 24 5.2 0.1 3.3 3 0 0 3 3 3 0 Human growth factor-like EGF Img2 PF05046.9 CBK24464.2 - 2e-10 40.7 0.0 3.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CBK24464.2 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 3Beta_HSD PF01073.14 CBK24464.2 - 0.029 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family L_protein_N PF15518.1 CBK24464.2 - 0.051 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus CLP_protease PF00574.18 CBK24464.2 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Clp protease WD40 PF00400.27 CBK24466.2 - 4.8e-16 57.9 1.3 6.6e-07 28.9 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CBK24466.2 - 0.00096 19.2 1.2 0.0017 18.4 0.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Ala_racemase_C PF00842.16 CBK24466.2 - 0.047 13.1 0.1 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Lgl_C PF08596.5 CBK24466.2 - 0.13 10.6 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Carb_kinase PF01256.12 CBK24467.2 - 4.3e-49 166.9 0.0 5.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase JAB PF01398.16 CBK24468.2 - 8.7e-33 112.4 0.1 1.3e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBK24468.2 - 3e-09 36.3 0.0 5.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CBK24468.2 - 0.0047 16.4 0.0 0.016 14.6 0.0 1.9 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0172) Nop52 PF05997.7 CBK24469.2 - 3.4e-54 183.5 8.2 4e-54 183.3 5.7 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 XPA_C PF05181.7 CBK24469.2 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 XPA protein C-terminus Ribosomal_L6 PF00347.18 CBK24470.2 - 8.3e-30 103.1 4.4 4.7e-15 55.8 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 TPR_11 PF13414.1 CBK24471.2 - 6.8e-18 64.0 0.0 1e-09 37.8 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBK24471.2 - 3.7e-14 51.4 0.0 0.0017 18.1 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBK24471.2 - 5e-13 48.0 0.0 0.00069 19.1 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBK24471.2 - 6e-10 38.8 0.0 0.031 14.8 0.0 5.4 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK24471.2 - 4.2e-09 36.8 0.0 0.00027 21.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24471.2 - 1.4e-07 31.3 0.0 0.017 15.0 0.0 4.0 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBK24471.2 - 6e-07 28.7 0.0 2.9 7.9 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK24471.2 - 1.2e-05 25.4 0.0 0.037 14.3 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK24471.2 - 9.6e-05 21.9 0.0 0.28 11.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBK24471.2 - 0.00021 21.1 0.4 1.4 8.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 CBK24471.2 - 0.00038 19.8 0.9 2.6 7.3 0.0 4.6 2 2 2 5 5 5 1 26S proteasome subunit RPN7 Apc3 PF12895.2 CBK24471.2 - 0.00046 20.2 0.0 17 5.6 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBK24471.2 - 0.0097 15.7 0.0 0.034 14.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK24471.2 - 0.011 15.9 0.1 1.7 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 CBK24471.2 - 0.09 12.7 1.3 26 5.0 0.0 3.8 3 1 1 4 4 4 0 PPR repeat HSP90 PF00183.13 CBK24472.2 - 1.2e-83 281.3 0.3 1.2e-83 281.3 0.2 2.9 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.1 CBK24472.2 - 2.6e-14 53.0 0.3 6.6e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBK24472.2 - 1.1e-07 31.5 0.1 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fibritin_C PF07921.7 CBK24472.2 - 0.016 15.0 0.3 0.044 13.6 0.2 1.7 1 0 0 1 1 1 0 Fibritin C-terminal region Cytochrom_C PF00034.16 CBK24472.2 - 0.06 14.1 0.2 1.9 9.3 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c Acyltransferase PF01553.16 CBK24473.2 - 5.2e-15 55.0 0.0 1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MORN_2 PF07661.8 CBK24474.2 - 0.38 10.9 0.0 0.38 10.9 0.0 3.7 4 0 0 4 4 4 0 MORN repeat variant LRR_8 PF13855.1 CBK24475.2 - 0.0064 16.2 1.0 0.056 13.2 0.1 2.9 2 1 1 3 3 3 1 Leucine rich repeat MORN PF02493.15 CBK24475.2 - 0.05 13.3 7.7 1.2 9.0 2.1 2.7 2 0 0 2 2 2 0 MORN repeat ABC_tran PF00005.22 CBK24476.2 - 1.6e-38 132.1 0.0 6.1e-22 78.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CBK24476.2 - 1.2e-21 77.1 26.4 1.9e-21 76.4 18.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBK24476.2 - 4.6e-21 76.0 0.7 1.1e-09 38.6 0.3 3.8 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBK24476.2 - 1.5e-08 34.1 1.0 0.09 11.9 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBK24476.2 - 1.4e-06 27.6 0.0 0.14 11.1 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain YtpI PF14007.1 CBK24476.2 - 0.0003 20.6 2.0 0.0059 16.4 0.2 2.9 2 0 0 2 2 2 1 YtpI-like protein SbcCD_C PF13558.1 CBK24476.2 - 0.00036 20.3 0.0 0.1 12.4 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PcfK PF14058.1 CBK24476.2 - 0.087 12.9 0.2 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein AAA_23 PF13476.1 CBK24476.2 - 0.16 12.2 9.6 0.24 11.6 4.3 2.6 2 1 0 2 2 2 0 AAA domain PA28_beta PF02252.13 CBK24477.2 - 6.9e-15 54.8 0.1 1.5e-11 44.0 0.1 2.4 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBK24477.2 - 0.059 13.5 0.6 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit KOW PF00467.24 CBK24478.2 - 2.7e-06 26.8 2.0 6.4e-06 25.6 1.4 1.7 1 0 0 1 1 1 1 KOW motif TmoB PF06234.7 CBK24478.2 - 0.054 13.3 0.3 0.26 11.1 0.0 2.1 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Ribosomal_L3 PF00297.17 CBK24479.2 - 1.8e-114 381.5 8.0 2.2e-114 381.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF912 PF06024.7 CBK24480.2 - 0.00026 20.9 2.3 0.55 10.3 0.1 2.5 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1673 PF07895.6 CBK24480.2 - 0.00043 19.8 1.2 0.0007 19.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) LRR_4 PF12799.2 CBK24480.2 - 0.0057 16.2 0.1 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Rifin_STEVOR PF02009.11 CBK24480.2 - 0.007 16.0 0.0 0.76 9.3 0.1 2.3 2 0 0 2 2 2 1 Rifin/stevor family Kei1 PF08552.6 CBK24480.2 - 0.019 14.6 0.2 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FAM176 PF14851.1 CBK24480.2 - 0.038 13.6 2.0 0.052 13.2 0.3 2.0 1 1 1 2 2 2 0 FAM176 family Protocadherin PF08374.6 CBK24480.2 - 0.042 13.5 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Protocadherin DUF3753 PF12575.3 CBK24480.2 - 2.2 8.1 12.6 0.19 11.5 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) POLO_box PF00659.13 CBK24481.2 - 0.037 14.0 0.0 87 3.2 0.0 3.6 3 0 0 3 3 3 0 POLO box duplicated region gag-asp_proteas PF13975.1 CBK24481.2 - 0.65 9.8 4.0 86 3.0 0.1 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease PORR PF11955.3 CBK24481.2 - 2.3 6.8 0.0 1.8e+02 0.6 0.0 2.7 3 0 0 3 3 3 0 Plant organelle RNA recognition domain AAA PF00004.24 CBK24482.2 - 4.9e-56 188.5 0.0 2.2e-41 141.1 0.0 2.9 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBK24482.2 - 3.9e-08 33.2 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBK24482.2 - 7.3e-08 33.2 0.0 0.0051 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBK24482.2 - 1.3e-07 31.8 0.0 0.00032 20.7 0.0 2.8 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 CBK24482.2 - 1e-06 28.5 0.1 0.0014 18.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK24482.2 - 1e-06 28.0 0.2 0.011 14.7 0.0 3.3 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK24482.2 - 2.1e-06 27.8 3.0 0.0042 17.2 0.3 4.1 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBK24482.2 - 3.4e-06 27.0 0.0 5.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CBK24482.2 - 4e-06 26.9 0.0 0.0081 16.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 CBK24482.2 - 4.9e-06 26.3 0.2 0.24 11.0 0.0 3.7 3 1 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 CBK24482.2 - 6.2e-06 26.0 0.3 0.31 10.7 0.1 4.2 2 2 1 4 4 4 1 Archaeal ATPase ABC_tran PF00005.22 CBK24482.2 - 6.7e-05 23.2 0.1 0.0041 17.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.12 CBK24482.2 - 7.3e-05 22.2 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CBK24482.2 - 8.3e-05 22.8 0.0 0.04 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK24482.2 - 0.00012 21.9 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBK24482.2 - 0.00018 21.1 0.0 0.081 12.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 CBK24482.2 - 0.00019 20.2 0.0 0.042 12.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 CBK24482.2 - 0.0003 20.2 0.0 0.89 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 CBK24482.2 - 0.00053 19.9 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBK24482.2 - 0.00084 18.5 0.2 0.0089 15.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CBK24482.2 - 0.0011 18.0 0.0 0.01 14.9 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.1 CBK24482.2 - 0.0022 17.5 2.0 0.071 12.6 0.0 3.2 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 CBK24482.2 - 0.0024 16.7 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 CBK24482.2 - 0.0029 17.0 4.1 0.53 9.6 0.0 3.9 2 2 1 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CBK24482.2 - 0.0075 15.3 0.0 0.74 8.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.11 CBK24482.2 - 0.01 15.0 0.0 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.17 CBK24482.2 - 0.012 15.4 0.0 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activ_2 PF14532.1 CBK24482.2 - 0.015 15.3 0.0 4.3 7.3 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 CBK24482.2 - 0.018 14.6 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBK24482.2 - 0.025 14.1 0.0 0.62 9.6 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 CBK24482.2 - 0.032 13.7 0.0 1 8.7 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 CBK24482.2 - 0.11 11.9 0.0 0.37 10.1 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain CENP-Q PF13094.1 CBK24483.2 - 0.0012 18.8 8.9 0.0017 18.3 6.1 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 CBK24483.2 - 0.0041 16.7 4.7 0.0056 16.3 3.2 1.1 1 0 0 1 1 1 1 Mnd1 family ATG16 PF08614.6 CBK24483.2 - 0.0084 15.9 5.2 0.011 15.5 3.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TBPIP PF07106.8 CBK24483.2 - 0.012 15.2 3.5 0.012 15.2 2.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3440 PF11922.3 CBK24483.2 - 0.017 14.7 0.4 0.022 14.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Fmp27_WPPW PF10359.4 CBK24483.2 - 0.04 12.3 4.9 0.045 12.1 3.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 CBK24483.2 - 0.15 9.8 3.7 0.17 9.6 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 CBK24483.2 - 0.23 10.6 12.3 0.045 12.9 3.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Elongin_A PF06881.6 CBK24483.2 - 0.53 10.6 5.2 0.2 12.0 1.7 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A APG6 PF04111.7 CBK24483.2 - 0.92 8.4 12.8 1.6 7.6 8.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 CBK24483.2 - 1.3 8.0 7.0 1.6 7.7 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 CBK24483.2 - 2.2 8.4 7.6 3.8 7.6 5.2 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 CBK24483.2 - 2.7 7.5 8.5 1.3 8.5 3.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Nsp1_C PF05064.8 CBK24483.2 - 3 7.5 9.5 2.2 7.9 2.7 2.2 1 1 2 3 3 3 0 Nsp1-like C-terminal region Seryl_tRNA_N PF02403.17 CBK24483.2 - 3.4 7.7 8.5 27 4.8 5.8 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 CBK24483.2 - 4.8 5.4 8.3 7 4.9 5.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 CBK24483.2 - 8.8 6.7 15.1 18 5.6 10.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Ssu72 PF04722.8 CBK24485.2 - 1e-52 178.3 0.0 1.3e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PB1-F2 PF11986.3 CBK24486.2 - 0.026 14.5 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Influenza A Proapoptotic protein Omptin PF01278.15 CBK24486.2 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Omptin family COG4 PF08318.7 CBK24487.2 - 1.2e-06 27.5 1.0 6.3e-06 25.1 0.7 2.1 1 1 0 1 1 1 1 COG4 transport protein TACC PF05010.9 CBK24487.2 - 0.0047 16.7 0.0 6.2 6.5 2.7 2.9 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) DUF544 PF04424.8 CBK24487.2 - 0.046 13.5 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF544) FTR_C PF02741.10 CBK24487.2 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 FTR, proximal lobe SRP1_TIP1 PF00660.12 CBK24487.2 - 0.052 13.3 0.2 0.39 10.5 0.0 2.5 3 0 0 3 3 3 0 Seripauperin and TIP1 family Sec10 PF07393.6 CBK24488.2 - 0.0018 16.5 0.3 0.002 16.4 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sec6 PF06046.8 CBK24488.2 - 0.039 12.0 0.2 0.043 11.8 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 Radical_SAM PF04055.16 CBK24489.2 - 4.9e-12 46.3 0.3 9.4e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF3792 PF12670.2 CBK24489.2 - 1.3 8.9 8.9 0.067 13.0 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) Actin PF00022.14 CBK24490.2 - 3.4e-89 299.0 0.0 6.3e-89 298.1 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK24490.2 - 0.0016 17.1 0.0 0.26 9.8 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein Ribosomal_S8e PF01201.17 CBK24491.2 - 2.8e-32 111.6 0.1 3.3e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e S-AdoMet_synt_M PF02772.11 CBK24492.2 - 0.044 13.7 0.0 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain PFK PF00365.15 CBK24494.2 - 8.5e-26 90.5 0.2 1.5e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Phosphofructokinase DUF2186 PF09952.4 CBK24494.2 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) NUDIX PF00293.23 CBK24495.2 - 3.6e-14 52.5 0.0 4.5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain EGF_2 PF07974.8 CBK24496.2 - 4e-16 58.8 90.0 0.00022 21.3 6.8 6.8 7 0 0 7 7 7 6 EGF-like domain EGF PF00008.22 CBK24496.2 - 1.1e-05 25.2 75.3 0.0012 18.7 4.6 6.8 6 0 0 6 6 6 5 EGF-like domain DSL PF01414.14 CBK24496.2 - 0.00013 21.8 19.3 0.00013 21.8 13.4 4.9 1 1 2 4 4 4 2 Delta serrate ligand Laminin_EGF PF00053.19 CBK24496.2 - 0.0013 18.5 79.5 0.64 9.9 8.2 6.3 2 2 4 6 6 6 4 Laminin EGF-like (Domains III and V) hEGF PF12661.2 CBK24496.2 - 0.011 15.7 38.6 0.31 11.2 3.0 6.4 5 0 0 5 5 5 0 Human growth factor-like EGF Lyase_1 PF00206.15 CBK24497.2 - 1e-23 84.0 0.0 1.6e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CBK24497.2 - 2.1e-15 56.4 0.0 8.1e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Mito_carr PF00153.22 CBK24498.2 - 2.5e-11 43.1 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 CBK24499.2 - 4.3e-19 68.0 0.0 2.2e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1510 PF07423.6 CBK24500.2 - 0.039 13.3 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ctr PF04145.10 CBK24500.2 - 0.42 10.6 3.8 0.71 9.9 2.6 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Sox_N PF12444.3 CBK24500.2 - 2.3 9.3 9.2 37 5.5 6.4 2.1 1 1 0 1 1 1 0 Sox developmental protein N terminal Spore_YhaL PF14147.1 CBK24501.2 - 0.01 15.2 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL LRRC37AB_C PF14914.1 CBK24501.2 - 0.016 14.6 0.2 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain HRM PF02793.17 CBK24501.2 - 0.02 14.8 0.3 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 Hormone receptor domain Glycoprotein_G PF00802.14 CBK24501.2 - 0.025 13.7 0.4 0.032 13.3 0.2 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Phi-29_GP16_7 PF06720.6 CBK24501.2 - 0.037 13.6 0.2 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 P12 PF12669.2 CBK24501.2 - 0.042 14.0 0.6 0.07 13.3 0.4 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family WBP-1 PF11669.3 CBK24501.2 - 0.057 13.5 0.9 0.076 13.0 0.7 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 RICTOR_V PF14668.1 CBK24502.2 - 7.2e-11 41.8 0.5 6.5e-10 38.8 0.2 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.1 CBK24503.2 - 1.6e-22 79.6 4.9 2e-22 79.2 3.4 1.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Acetyltransf_1 PF00583.19 CBK24504.2 - 7.5e-08 32.3 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBK24504.2 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Choline_transpo PF04515.7 CBK24505.2 - 1.8e-58 197.9 33.4 3.1e-58 197.1 23.1 1.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter Methyltransf_4 PF02390.12 CBK24506.2 - 1e-34 119.3 0.0 1.3e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CBK24506.2 - 7.9e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBK24506.2 - 0.00022 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CBK24506.2 - 0.00042 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBK24506.2 - 0.0009 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBK24506.2 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK24506.2 - 0.0024 18.4 0.0 0.0032 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK24506.2 - 0.003 17.8 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain YlzJ PF14035.1 CBK24506.2 - 0.0031 17.5 0.1 0.0082 16.1 0.0 1.7 1 0 0 1 1 1 1 YlzJ-like protein CheR PF01739.13 CBK24506.2 - 0.0036 16.6 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Zds_C PF08632.5 CBK24506.2 - 0.013 14.8 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term RrnaAD PF00398.15 CBK24506.2 - 0.015 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FmrO PF07091.6 CBK24506.2 - 0.039 12.9 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 CBK24506.2 - 0.04 14.3 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CBK24506.2 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBK24506.2 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CBK24506.2 - 0.15 11.1 0.2 0.3 10.1 0.1 1.5 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Kdo_hydroxy PF11004.3 CBK24507.2 - 0.055 12.4 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase TPR_14 PF13428.1 CBK24508.2 - 0.00015 22.1 0.1 93 4.0 0.0 6.2 3 3 4 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK24508.2 - 0.00017 22.1 0.0 5.3 7.8 0.0 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK24508.2 - 0.0042 17.1 0.8 1.5 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3275 PF11679.3 CBK24508.2 - 0.014 15.0 3.6 0.03 13.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Suf PF05843.9 CBK24508.2 - 0.037 13.7 27.9 0.25 11.0 0.0 3.6 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) BOFC_N PF08977.5 CBK24508.2 - 0.06 13.1 4.3 4.6 7.1 0.0 4.1 4 0 0 4 4 4 0 Bypass of Forespore C, N terminal FHIPEP PF00771.15 CBK24508.2 - 0.25 9.6 7.5 0.36 9.0 5.2 1.1 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.4 CBK24508.2 - 0.91 7.6 41.9 1.4 7.0 29.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF912 PF06024.7 CBK24508.2 - 3.8 7.6 6.6 13 5.9 4.6 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Helicase_C_3 PF13625.1 CBK24509.2 - 5.3e-16 58.5 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBK24509.2 - 6.9e-15 55.3 0.0 2.1e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBK24509.2 - 8.3e-09 35.2 0.2 3.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBK24509.2 - 6.8e-06 25.0 0.0 1.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CBK24509.2 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase B56 PF01603.15 CBK24510.2 - 7.5e-17 61.0 6.1 5.5e-16 58.1 3.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Glycos_transf_1 PF00534.15 CBK24511.2 - 1.9e-26 92.5 0.0 3.5e-26 91.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBK24511.2 - 4.8e-13 49.1 0.0 8.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CBK24511.2 - 1.5e-12 47.9 0.0 3.8e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CBK24511.2 - 2.1e-12 47.3 0.0 2.1e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CBK24511.2 - 0.0016 18.2 0.0 0.0093 15.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CBK24511.2 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 NmrA PF05368.8 CBK24511.2 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family PS_pyruv_trans PF04230.8 CBK24511.2 - 0.038 13.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Glycos_transf_N PF04413.11 CBK24511.2 - 0.046 12.8 0.0 4.4 6.4 0.0 3.3 4 0 0 4 4 4 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Toprim_3 PF13362.1 CBK24511.2 - 0.06 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Toprim domain adh_short_C2 PF13561.1 CBK24512.2 - 1.7e-22 80.3 0.4 2.6e-22 79.7 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBK24512.2 - 1.3e-20 74.0 0.1 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBK24512.2 - 1.4e-06 28.0 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBK24512.2 - 0.01 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CBK24512.2 - 0.058 12.5 0.0 0.33 10.0 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Methyltransf_28 PF02636.12 CBK24513.2 - 4.4e-11 42.6 0.0 1.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MRG PF05712.8 CBK24514.2 - 1.1e-19 70.1 5.7 1.4e-19 69.7 4.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CBK24514.2 - 1.5e-08 34.1 0.5 4.9e-08 32.5 0.4 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CBK24514.2 - 0.0091 15.6 0.7 0.029 14.0 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Snf7 PF03357.16 CBK24515.2 - 2.8e-26 91.9 8.5 3.6e-26 91.5 5.9 1.1 1 0 0 1 1 1 1 Snf7 GLE1 PF07817.8 CBK24515.2 - 0.043 12.7 1.4 0.069 12.0 1.0 1.3 1 0 0 1 1 1 0 GLE1-like protein GED PF02212.13 CBK24515.2 - 0.32 10.9 3.8 0.59 10.0 0.0 2.6 2 1 0 2 2 2 0 Dynamin GTPase effector domain Phage_GP20 PF06810.6 CBK24515.2 - 0.91 8.9 7.1 0.51 9.7 2.3 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.15 CBK24515.2 - 3.8 7.3 9.5 0.37 10.5 2.2 2.5 3 0 0 3 3 3 0 Prefoldin subunit GalKase_gal_bdg PF10509.4 CBK24516.2 - 1.9e-22 78.3 0.1 3.7e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CBK24516.2 - 2.4e-11 43.5 3.1 5.6e-11 42.3 2.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBK24516.2 - 4.4e-10 39.6 0.4 3.9e-09 36.5 0.3 2.5 1 1 0 1 1 1 1 GHMP kinases C terminal Adaptin_N PF01602.15 CBK24517.2 - 1.5e-73 247.9 1.0 1.9e-73 247.6 0.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBK24517.2 - 2.5e-40 137.7 0.0 4.5e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBK24517.2 - 6.6e-06 26.3 20.0 0.00043 20.5 0.6 4.7 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 CBK24517.2 - 0.0052 16.7 16.2 1.1 9.4 0.7 5.9 5 0 0 5 5 5 2 HEAT repeat DUF2013 PF09431.5 CBK24517.2 - 0.091 12.5 0.3 0.25 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) HEAT_EZ PF13513.1 CBK24517.2 - 0.36 11.3 28.1 0.24 11.9 3.6 6.5 5 1 0 5 5 5 0 HEAT-like repeat HEAT_PBS PF03130.11 CBK24517.2 - 0.45 11.1 5.5 3.2 8.4 1.4 3.9 2 1 1 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.18 CBK24517.2 - 0.78 9.6 4.2 3 7.7 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RGS PF00615.14 CBK24518.2 - 1.4e-06 28.4 0.2 1.7e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Nol1_Nop2_Fmu PF01189.12 CBK24520.2 - 2.2e-07 30.5 0.0 2.6e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CBK24520.2 - 0.00019 21.0 0.0 0.00076 19.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CBK24520.2 - 0.0013 17.8 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CBK24520.2 - 0.035 14.6 0.0 0.04 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CBK24520.2 - 0.052 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 CBK24520.2 - 0.095 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MutS_V PF00488.16 CBK24521.2 - 4.5e-81 271.7 0.0 1.3e-80 270.1 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CBK24521.2 - 3e-40 138.2 0.1 5.7e-40 137.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CBK24521.2 - 1.7e-30 105.3 0.2 3.5e-30 104.3 0.2 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CBK24521.2 - 5.3e-13 48.9 0.2 1.9e-12 47.2 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CBK24521.2 - 9.6e-08 32.1 0.2 6.9e-06 26.1 0.0 3.1 2 1 0 2 2 2 1 MutS domain II DUF2400 PF09674.5 CBK24521.2 - 0.015 15.0 1.3 0.04 13.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) ABC_tran PF00005.22 CBK24521.2 - 0.042 14.1 0.5 13 6.1 0.2 2.8 2 0 0 2 2 2 0 ABC transporter Sec1 PF00995.18 CBK24524.2 - 1.6e-119 400.1 0.0 1.9e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GTP_EFTU PF00009.22 CBK24525.2 - 3.6e-18 65.6 0.0 5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBK24525.2 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBK24525.2 - 7.7e-06 26.3 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBK24525.2 - 8.1e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 CBK24525.2 - 0.00033 20.1 0.2 0.013 14.9 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBK24525.2 - 0.0033 16.4 0.0 0.31 10.0 0.0 2.2 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.12 CBK24525.2 - 0.016 14.7 0.0 0.064 12.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 CBK24525.2 - 0.022 14.0 0.0 0.15 11.3 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 CBK24525.2 - 0.027 14.3 0.0 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Arf PF00025.16 CBK24525.2 - 0.029 13.5 0.1 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family NadA PF02445.11 CBK24525.2 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein C2 PF00168.25 CBK24527.2 - 3.8e-16 58.6 0.0 9.8e-16 57.3 0.0 1.7 2 0 0 2 2 2 1 C2 domain YbjQ_1 PF01906.12 CBK24527.2 - 0.0023 18.3 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative heavy-metal-binding YccV-like PF08755.6 CBK24527.2 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Isochorismatase PF00857.15 CBK24528.2 - 2.4e-29 102.5 0.4 3.3e-29 102.0 0.3 1.2 1 0 0 1 1 1 1 Isochorismatase family HSF_DNA-bind PF00447.12 CBK24529.2 - 3.1e-27 94.7 0.4 3.1e-27 94.7 0.3 1.7 2 0 0 2 2 1 1 HSF-type DNA-binding S1 PF00575.18 CBK24529.2 - 6.9e-10 38.8 0.1 1.3e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain TPR_19 PF14559.1 CBK24529.2 - 1.4e-08 34.8 0.9 0.055 13.8 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 CBK24529.2 - 8.8e-07 28.9 1.3 0.0042 16.8 0.3 3.5 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CBK24529.2 - 1.3e-05 25.4 12.6 0.0013 19.2 1.1 4.6 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBK24529.2 - 0.00017 22.1 8.1 0.022 15.4 0.3 3.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24529.2 - 0.00021 21.1 0.6 0.52 10.2 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Collagen PF01391.13 CBK24529.2 - 0.00037 19.9 11.1 0.00065 19.1 7.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_6 PF13174.1 CBK24529.2 - 0.0095 16.3 0.6 2.2 8.9 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK24529.2 - 0.032 13.8 1.0 0.26 10.9 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CBK24529.2 - 0.042 13.7 0.3 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBK24529.2 - 0.047 13.9 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.22 CBK24530.2 - 2.2e-67 222.8 2.8 1.2e-23 82.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Isochorismatase PF00857.15 CBK24530.2 - 2.5e-12 47.0 0.0 1.1e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family Ribosomal_L13e PF01294.13 CBK24531.2 - 1.7e-34 118.8 0.3 1.3e-33 115.9 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein L13e ubiquitin PF00240.18 CBK24532.2 - 6.5e-35 118.3 0.7 1.4e-34 117.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CBK24532.2 - 1.8e-24 85.2 2.8 3.5e-24 84.3 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CBK24532.2 - 1.1e-19 69.8 0.7 1.1e-19 69.8 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBK24532.2 - 7.8e-06 26.0 0.7 2.8e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBK24532.2 - 0.00019 21.1 0.6 0.0003 20.5 0.0 1.5 1 1 1 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBK24532.2 - 0.00023 21.0 1.0 0.00049 19.9 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK24532.2 - 0.0012 18.9 0.7 0.0016 18.5 0.5 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain zf-ribbon_3 PF13248.1 CBK24532.2 - 0.006 15.7 3.0 0.013 14.7 2.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBK24532.2 - 0.017 14.9 0.4 0.026 14.3 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 CBK24532.2 - 0.036 13.9 0.9 0.056 13.3 0.6 1.4 1 1 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CBK24532.2 - 0.053 13.5 1.0 0.1 12.6 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CBK24532.2 - 0.084 11.1 3.9 0.39 8.9 0.3 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zinc_ribbon_2 PF13240.1 CBK24532.2 - 0.37 10.3 3.4 9.3 5.8 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK24532.2 - 1.1 8.8 5.0 4.6 6.9 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBK24532.2 - 2.5 7.8 5.5 4.3 7.1 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain P34-Arc PF04045.9 CBK24533.2 - 1.8e-37 128.8 0.0 2.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 CBK24534.2 - 2e-22 78.1 13.4 1.5e-08 34.1 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 CBK24535.2 - 1.1e-12 47.2 6.1 7.1e-06 25.6 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat DUF543 PF04418.7 CBK24535.2 - 0.028 14.3 2.0 0.036 14.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) CPSF_A PF03178.10 CBK24535.2 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region Lactamase_B_2 PF12706.2 CBK24536.2 - 4.2e-19 68.8 0.0 1.3e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBK24536.2 - 3.4e-08 33.3 0.0 6.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 CBK24536.2 - 0.0083 15.0 0.1 0.046 12.6 0.0 1.9 2 0 0 2 2 2 1 cAMP phosphodiesterases class-II CM2 PF03021.9 CBK24536.2 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein TRM PF02005.11 CBK24537.2 - 4.6e-15 55.4 0.0 5.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TRM PF02005.11 CBK24538.2 - 2.5e-75 253.7 0.2 3e-75 253.4 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.6 CBK24538.2 - 0.0013 17.5 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CBK24538.2 - 0.0032 17.0 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBK24538.2 - 0.015 14.9 0.0 0.028 13.9 0.0 1.4 1 1 0 1 1 1 0 Met-10+ like-protein ecTbetaR2 PF08917.5 CBK24538.2 - 0.37 10.5 3.2 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain MIP-T3 PF10243.4 CBK24539.2 - 1.1 7.7 54.3 1.8 6.9 37.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_13 PF13166.1 CBK24540.2 - 0.00031 19.3 15.0 0.00031 19.3 10.4 1.9 1 1 1 2 2 2 2 AAA domain NPV_P10 PF05531.7 CBK24540.2 - 0.0013 18.9 1.9 1.2 9.4 0.0 3.8 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 CBK24540.2 - 0.0078 16.0 26.2 0.11 12.2 6.9 2.2 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) Mnd1 PF03962.10 CBK24540.2 - 0.013 15.2 6.7 0.013 15.2 4.6 2.8 1 1 1 2 2 2 0 Mnd1 family Vps51 PF08700.6 CBK24540.2 - 0.019 14.7 0.4 0.019 14.7 0.3 4.3 4 1 2 6 6 5 0 Vps51/Vps67 TPR_MLP1_2 PF07926.7 CBK24540.2 - 0.022 14.5 29.0 0.026 14.2 4.4 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 CBK24540.2 - 0.023 14.6 30.2 0.22 11.4 4.2 5.0 4 1 1 5 5 5 0 bZIP transcription factor WXG100 PF06013.7 CBK24540.2 - 0.039 13.9 10.2 5.5 7.0 0.3 4.3 3 1 1 4 4 4 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 CBK24540.2 - 0.039 14.0 19.1 0.035 14.2 3.6 4.1 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2935 PF11155.3 CBK24540.2 - 0.048 13.7 14.5 4.7 7.3 0.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) TBPIP PF07106.8 CBK24540.2 - 0.11 12.0 27.7 0.03 13.8 5.1 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlgN PF05130.7 CBK24540.2 - 0.11 12.7 22.2 0.1 12.8 4.1 2.4 2 1 0 2 2 2 0 FlgN protein CENP-F_leu_zip PF10473.4 CBK24540.2 - 0.11 12.3 32.9 0.77 9.6 4.3 3.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CBK24540.2 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Cytochrom_B562 PF07361.6 CBK24540.2 - 0.13 12.7 12.7 0.039 14.3 2.9 2.9 1 1 1 2 2 2 0 Cytochrome b562 CDC37_N PF03234.9 CBK24540.2 - 0.14 12.4 21.3 0.086 13.1 9.8 2.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding IncA PF04156.9 CBK24540.2 - 0.15 11.6 31.9 0.35 10.4 10.4 2.7 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 CBK24540.2 - 0.2 10.6 31.7 0.046 12.7 13.1 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 SlyX PF04102.7 CBK24540.2 - 0.26 11.6 20.1 2.5 8.5 3.6 4.6 3 1 1 4 4 4 0 SlyX Cep57_CLD_2 PF14197.1 CBK24540.2 - 0.38 10.7 19.6 0.099 12.5 1.9 4.3 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.7 CBK24540.2 - 0.4 10.5 3.8 8.2 6.2 0.2 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 CBK24540.2 - 0.44 8.9 2.1 0.68 8.2 1.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 CBK24540.2 - 0.49 8.7 24.6 0.035 12.5 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2400 PF09674.5 CBK24540.2 - 0.65 9.6 8.1 0.25 11.0 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) ADIP PF11559.3 CBK24540.2 - 0.68 9.8 27.7 1.2 8.9 7.3 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 CBK24540.2 - 0.69 9.7 14.4 0.7 9.7 2.9 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 CBK24540.2 - 0.76 9.6 26.7 0.42 10.4 4.4 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBK24540.2 - 0.82 9.1 30.3 0.99 8.9 3.8 4.4 3 1 1 4 4 4 0 Septum formation initiator DUF972 PF06156.8 CBK24540.2 - 0.9 9.9 22.6 1.7 8.9 1.5 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Syntaxin_2 PF14523.1 CBK24540.2 - 0.97 9.4 14.9 6.2 6.9 7.1 2.8 1 1 2 3 3 3 0 Syntaxin-like protein Seryl_tRNA_N PF02403.17 CBK24540.2 - 1.1 9.2 25.1 0.88 9.6 4.4 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 CBK24540.2 - 1.2 8.9 13.8 1.4 8.7 1.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.1 CBK24540.2 - 1.3 8.1 27.3 0.61 9.2 7.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HOOK PF05622.7 CBK24540.2 - 1.9 6.2 30.3 0.12 10.2 9.6 2.2 1 1 1 2 2 2 0 HOOK protein Fib_alpha PF08702.5 CBK24540.2 - 1.9 8.5 18.5 1.6 8.8 4.2 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.7 CBK24540.2 - 2.1 7.6 24.6 0.1 11.9 1.0 3.4 2 2 1 3 3 3 0 PspA/IM30 family Tropomyosin PF00261.15 CBK24540.2 - 2.6 7.0 29.3 5.2 6.0 12.3 3.1 1 1 2 3 3 3 0 Tropomyosin Tropomyosin_1 PF12718.2 CBK24540.2 - 2.6 7.8 35.9 0.25 11.1 7.2 3.8 1 1 0 3 3 3 0 Tropomyosin like CASP_C PF08172.7 CBK24540.2 - 2.7 6.9 21.9 6.9 5.6 7.7 2.9 2 1 0 2 2 2 0 CASP C terminal ACCA PF03255.9 CBK24540.2 - 3 7.4 13.0 0.5 9.9 0.3 3.6 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Laminin_II PF06009.7 CBK24540.2 - 3.5 7.3 12.6 0.49 10.1 1.2 3.1 2 2 2 4 4 4 0 Laminin Domain II FlxA PF14282.1 CBK24540.2 - 3.8 7.5 24.7 0.11 12.4 6.0 3.6 2 1 0 2 2 1 0 FlxA-like protein DUF479 PF04336.7 CBK24540.2 - 3.9 7.6 8.2 1.3 9.1 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function, DUF479 CCDC-167 PF15188.1 CBK24540.2 - 4.6 7.2 27.1 0.057 13.3 5.7 3.5 2 1 2 4 4 4 0 Coiled-coil domain-containing protein 167 TMF_TATA_bd PF12325.3 CBK24540.2 - 4.8 6.9 29.0 0.72 9.6 5.1 4.1 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Cauli_AT PF03233.8 CBK24540.2 - 5.2 6.7 13.2 4 7.1 1.2 2.7 1 1 2 3 3 3 0 Aphid transmission protein DivIVA PF05103.8 CBK24540.2 - 6 6.9 28.0 6.4 6.8 2.0 4.4 1 1 3 4 4 4 0 DivIVA protein Spectrin PF00435.16 CBK24540.2 - 6.1 7.1 23.8 5 7.4 2.0 3.5 1 1 2 3 3 3 0 Spectrin repeat FlpD PF02662.11 CBK24540.2 - 6.4 6.4 6.4 2.5 7.8 0.2 2.6 2 1 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit CorA PF01544.13 CBK24540.2 - 6.6 5.6 12.4 5.4 5.9 6.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.3 CBK24540.2 - 7.7 5.7 23.9 6.6 5.9 5.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 CBK24540.2 - 9.9 3.8 21.9 5.7 4.6 3.9 2.1 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Myb_DNA-binding PF00249.26 CBK24541.2 - 0.00016 21.6 0.3 0.00016 21.6 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK24541.2 - 0.13 12.4 0.4 0.13 12.4 0.3 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain KAT11 PF08214.6 CBK24542.2 - 4.3e-28 98.3 2.7 5.7e-28 97.9 1.9 1.1 1 0 0 1 1 1 1 Histone acetylation protein HSP70 PF00012.15 CBK24543.2 - 8.1e-223 740.7 4.5 9.9e-223 740.4 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24543.2 - 5.3e-12 44.9 0.0 1.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 CBK24543.2 - 0.0049 15.7 0.0 0.45 9.3 0.0 2.5 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBK24543.2 - 0.064 12.3 0.2 1.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase UvsW PF11637.3 CBK24543.2 - 0.14 11.8 2.8 0.13 11.9 0.5 2.0 1 1 1 2 2 2 0 ATP-dependant DNA helicase UvsW His_Phos_2 PF00328.17 CBK24544.2 - 4.2e-15 55.9 0.0 1.5e-14 54.1 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YjeF_N PF03853.10 CBK24546.2 - 5.4e-35 120.4 0.0 8.2e-35 119.8 0.0 1.3 1 1 0 1 1 1 1 YjeF-related protein N-terminus DUF1625 PF07787.7 CBK24548.2 - 5.5e-07 29.0 0.1 5.5e-07 29.0 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1625) PRKCSH-like PF12999.2 CBK24549.2 - 4.2e-37 127.4 7.2 4.6e-37 127.2 5.0 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 CBK24549.2 - 2.2e-07 30.6 14.5 0.00068 19.4 0.9 2.6 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A zf-UBR PF02207.15 CBK24549.2 - 3.1 7.5 12.3 11 5.8 0.8 2.4 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) PRKCSH_1 PF13015.1 CBK24550.2 - 1e-18 67.2 0.8 2e-18 66.3 0.5 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Peptidase_M4 PF01447.13 CBK24550.2 - 0.064 13.3 0.0 0.2 11.7 0.0 1.7 1 1 1 2 2 2 0 Thermolysin metallopeptidase, catalytic domain DUF4248 PF14053.1 CBK24550.2 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) PRKCSH PF07915.8 CBK24550.2 - 0.13 13.0 4.7 0.28 12.0 2.8 1.9 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein HEAT_2 PF13646.1 CBK24551.2 - 9e-05 22.6 0.4 2.7 8.3 0.1 3.9 3 0 0 3 3 3 2 HEAT repeats Ribosomal_L38e PF01781.13 CBK24552.2 - 2.1e-26 91.4 1.0 2.1e-26 91.4 0.7 1.8 2 0 0 2 2 2 1 Ribosomal L38e protein family BRK PF07533.11 CBK24552.2 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 BRK domain Laminin_II PF06009.7 CBK24552.2 - 0.047 13.4 0.1 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Laminin Domain II HALZ PF02183.13 CBK24553.2 - 0.01 15.5 12.0 0.24 11.1 0.3 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper CCDC155 PF14662.1 CBK24553.2 - 0.022 14.3 14.7 0.14 11.7 10.2 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 CBK24553.2 - 0.023 14.1 10.3 1.3 8.5 0.1 3.5 2 1 1 3 3 3 0 Septum formation initiator LRR_6 PF13516.1 CBK24553.2 - 0.039 14.0 13.7 2.8 8.2 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat ATG16 PF08614.6 CBK24553.2 - 0.093 12.5 12.8 0.18 11.6 8.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 CBK24553.2 - 0.16 11.7 15.7 1.7 8.4 0.2 4.5 3 1 1 4 4 4 0 Basic region leucine zipper DivIVA PF05103.8 CBK24553.2 - 0.23 11.5 10.0 0.087 12.8 4.2 2.1 1 1 1 2 2 2 0 DivIVA protein Nif11 PF07862.6 CBK24553.2 - 0.27 11.2 3.2 2.5 8.1 0.8 2.7 1 1 1 2 2 2 0 Nitrogen fixation protein of unknown function YscO PF07321.7 CBK24553.2 - 0.27 11.0 10.5 0.56 10.0 1.4 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO V_ATPase_I PF01496.14 CBK24553.2 - 0.48 8.2 6.3 0.73 7.6 4.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myosin_tail_1 PF01576.14 CBK24553.2 - 0.49 8.0 16.4 0.88 7.2 6.9 1.8 1 1 1 2 2 2 0 Myosin tail Mod_r PF07200.8 CBK24553.2 - 0.57 10.0 12.9 4 7.3 2.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 CBK24553.2 - 1.3 8.9 18.4 3.8 7.3 7.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 CBK24553.2 - 1.7 7.7 8.3 10 5.1 0.1 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SlyX PF04102.7 CBK24553.2 - 1.8 8.9 11.0 0.36 11.2 0.2 2.8 2 1 0 2 2 2 0 SlyX Spc42p PF11544.3 CBK24553.2 - 2 8.4 8.8 0.041 13.8 0.7 2.2 3 0 0 3 3 2 0 Spindle pole body component Spc42p TPR_MLP1_2 PF07926.7 CBK24553.2 - 2.5 7.8 16.2 5 6.8 10.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein End3 PF12761.2 CBK24553.2 - 2.7 7.5 13.1 5.8 6.4 2.8 2.4 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 IncA PF04156.9 CBK24553.2 - 5 6.6 20.7 0.85 9.1 4.8 2.2 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 CBK24553.2 - 7.3 4.8 6.3 10 4.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CBK24553.2 - 7.5 5.4 14.9 3.7 6.4 7.4 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 CBK24554.2 - 2.2e-05 23.7 0.0 2.2e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ins_beta PF03488.9 CBK24555.2 - 0.00064 19.4 1.7 0.12 12.1 0.0 3.4 3 0 0 3 3 3 2 Nematode insulin-related peptide beta type DUF3245 PF11595.3 CBK24556.2 - 0.00077 19.7 10.0 0.0048 17.1 6.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) G-patch_2 PF12656.2 CBK24556.2 - 0.004 16.9 1.0 0.009 15.8 0.0 2.0 2 1 0 2 2 2 1 DExH-box splicing factor binding site Ribosomal_L12 PF00542.14 CBK24557.2 - 2.6e-19 69.0 6.4 2.6e-19 69.0 4.4 2.9 2 1 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain DUF2259 PF10016.4 CBK24557.2 - 0.017 14.8 0.4 0.027 14.1 0.3 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Ribosomal_60s PF00428.14 CBK24557.2 - 0.026 14.9 10.8 0.026 14.9 7.5 3.2 3 1 0 3 3 3 0 60s Acidic ribosomal protein RRN3 PF05327.6 CBK24558.2 - 0.085 10.9 5.8 0.089 10.8 4.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rtf2 PF04641.7 CBK24558.2 - 0.12 11.6 3.5 0.16 11.1 2.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NESP55 PF06390.7 CBK24558.2 - 0.31 10.3 4.3 0.4 10.0 3.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CDC45 PF02724.9 CBK24558.2 - 0.75 7.7 8.2 0.72 7.8 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CTDII PF01556.13 CBK24559.2 - 5.1e-12 45.5 0.1 1.9e-11 43.6 0.0 2.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBK24559.2 - 0.00042 20.2 1.2 0.00089 19.2 0.9 1.5 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 CBK24559.2 - 0.63 9.5 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain BRX_N PF13713.1 CBK24560.2 - 0.9 9.0 2.8 8.1 6.0 0.2 2.2 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain IP_trans PF02121.13 CBK24561.2 - 7.6e-57 192.3 2.2 3.7e-56 190.1 1.5 1.9 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein Ssl1 PF04056.9 CBK24561.2 - 1.3e-41 142.2 0.7 2.2e-41 141.5 0.5 1.4 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CBK24561.2 - 1.2e-05 25.2 19.3 1.2e-05 25.2 13.4 3.4 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 CBK24561.2 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Vps26 PF03643.10 CBK24562.2 - 7.4e-84 280.7 6.0 8.6e-84 280.5 4.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CBK24562.2 - 0.0018 18.1 1.3 0.11 12.2 0.1 2.9 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CBK24562.2 - 0.019 15.0 0.7 0.11 12.6 0.1 2.2 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Tubulin PF00091.20 CBK24563.2 - 7.1e-70 235.1 0.0 1.8e-69 233.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBK24563.2 - 1.4e-37 128.5 0.0 3.8e-37 127.1 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBK24563.2 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain EF-hand_3 PF09069.6 CBK24563.2 - 0.023 14.7 0.1 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand Ribosomal_L20 PF00453.13 CBK24564.2 - 9.9e-35 118.7 8.2 1.2e-34 118.5 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L24e PF01246.15 CBK24566.2 - 2.7e-23 81.6 1.7 2.7e-23 81.6 1.2 1.9 1 1 1 2 2 2 1 Ribosomal protein L24e Pox_P4B PF03292.9 CBK24566.2 - 1.8 6.4 5.6 2 6.2 3.9 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein FragX_IP PF05994.6 CBK24568.2 - 1.4e-18 66.0 0.5 2.7e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family Pkinase PF00069.20 CBK24570.2 - 7e-68 228.5 0.0 9.1e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24570.2 - 1.8e-30 105.8 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CBK24570.2 - 7.5e-20 70.5 10.7 1.6e-19 69.5 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arb2 PF09757.4 CBK24570.2 - 8.6e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain FYVE_2 PF02318.11 CBK24570.2 - 0.00077 19.3 7.6 0.0019 18.0 5.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.1 CBK24570.2 - 0.0016 17.4 0.0 0.0042 16.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBK24570.2 - 0.024 13.7 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CBK24571.2 - 1.1e-20 72.6 0.9 1.7e-06 27.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK24571.2 - 0.062 11.4 0.1 0.098 10.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 COPIIcoated_ERV PF07970.7 CBK24572.2 - 1.1e-55 188.7 0.2 1.6e-55 188.1 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBK24572.2 - 1.8e-29 101.5 0.1 4.1e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Syntaxin-18_N PF10496.4 CBK24573.2 - 0.021 14.6 1.3 0.021 14.6 0.9 4.4 4 1 1 5 5 5 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.6 CBK24573.2 - 0.65 9.9 7.2 6.1 6.8 0.0 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 CBK24573.2 - 1.1 8.3 8.7 3.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein FTCD_N PF07837.7 CBK24574.2 - 5.5e-72 241.0 0.0 8.7e-72 240.3 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 CBK24574.2 - 1.2e-61 207.3 0.0 2.4e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.9 CBK24574.2 - 9.6e-56 187.4 0.1 1.6e-55 186.6 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain Ribosomal_L28e PF01778.12 CBK24575.2 - 6.9e-05 23.2 2.0 6.9e-05 23.2 1.4 2.0 1 1 1 2 2 2 1 Ribosomal L28e protein family Transglut_prok PF09017.5 CBK24575.2 - 0.0059 15.7 1.4 0.0067 15.5 1.0 1.0 1 0 0 1 1 1 1 Microbial transglutaminase Pkinase PF00069.20 CBK24576.2 - 7.3e-24 84.3 0.0 8.3e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24576.2 - 2.7e-18 65.9 0.0 3e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK24576.2 - 0.00036 20.3 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK24576.2 - 0.0036 16.3 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBK24576.2 - 0.0097 15.4 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CBK24576.2 - 0.025 13.6 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBK24576.2 - 0.066 12.0 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CBK24576.2 - 0.095 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3446 PF11928.3 CBK24577.2 - 0.03 14.5 9.3 0.03 14.5 6.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) AMPKBI PF04739.10 CBK24578.2 - 3.9e-23 81.2 0.7 6.5e-23 80.5 0.5 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain RabGAP-TBC PF00566.13 CBK24579.2 - 9.3e-41 139.6 2.8 7.2e-40 136.7 1.9 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain AAA_33 PF13671.1 CBK24580.2 - 4.1e-22 78.6 0.2 3.4e-21 75.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBK24580.2 - 1.7e-07 30.7 0.1 0.0023 17.2 0.0 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBK24580.2 - 1.2e-06 27.7 0.0 0.00031 19.8 0.0 2.1 1 1 1 2 2 2 2 Zeta toxin AAA_16 PF13191.1 CBK24580.2 - 2.1e-05 24.5 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBK24580.2 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 CBK24580.2 - 0.0038 16.3 0.0 0.46 9.5 0.0 2.5 1 1 2 3 3 3 1 6-phosphofructo-2-kinase ABC_tran PF00005.22 CBK24580.2 - 0.0079 16.5 0.0 0.0097 16.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 CBK24580.2 - 0.011 16.5 0.0 0.019 15.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBK24580.2 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBK24580.2 - 0.036 14.2 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PNK3P PF08645.6 CBK24580.2 - 0.039 13.3 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase AAA_14 PF13173.1 CBK24580.2 - 0.042 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 CBK24580.2 - 0.046 12.4 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.1 CBK24580.2 - 0.052 13.8 0.0 0.19 12.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBK24580.2 - 0.069 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CBK24580.2 - 0.069 12.5 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 CBK24580.2 - 0.16 11.3 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain LSM PF01423.17 CBK24581.2 - 3.6e-07 29.6 0.3 0.00048 19.6 0.0 2.2 2 0 0 2 2 2 2 LSM domain CactinC_cactus PF09732.4 CBK24582.2 - 2.6e-51 172.4 9.1 4.1e-51 171.7 6.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 CBK24582.2 - 2e-22 79.4 0.7 3.2e-22 78.7 0.2 1.5 1 1 0 1 1 1 1 Conserved mid region of cactin DUF3299 PF11736.3 CBK24582.2 - 0.026 14.4 1.8 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) BOP1NT PF08145.7 CBK24584.2 - 2.2e-46 158.6 5.9 6.9e-46 157.0 4.1 1.7 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CBK24584.2 - 6.7e-18 63.8 3.4 1.9e-05 24.3 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat TCP PF03634.8 CBK24584.2 - 0.017 15.4 0.3 0.055 13.8 0.2 1.9 1 0 0 1 1 1 0 TCP family transcription factor eIF2A PF08662.6 CBK24584.2 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A V-ATPase_C PF03223.10 CBK24585.2 - 4.2e-77 259.5 0.6 5.3e-77 259.2 0.4 1.1 1 0 0 1 1 1 1 V-ATPase subunit C SH3_9 PF14604.1 CBK24586.2 - 1.9e-16 59.3 0.1 4.2e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBK24586.2 - 1.2e-14 53.3 0.0 2.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBK24586.2 - 5.2e-11 41.8 0.0 1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 CBK24586.2 - 8e-09 35.3 12.4 1.1e-08 34.8 8.6 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 CBK24586.2 - 0.00019 20.8 10.0 0.00028 20.3 6.9 1.2 1 0 0 1 1 1 1 Arfaptin-like domain Fe_hyd_SSU PF02256.12 CBK24586.2 - 0.095 12.7 0.1 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit DUF4611 PF15387.1 CBK24586.2 - 1.9 8.7 5.9 1.3 9.1 1.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Ribosomal_L14e PF01929.12 CBK24587.2 - 8.4e-27 93.3 4.7 1.1e-26 92.9 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CBK24587.2 - 0.0012 18.4 0.1 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 KOW motif HMG_CoA_synt_C PF08540.5 CBK24587.2 - 0.015 14.7 0.0 0.018 14.5 0.0 1.0 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal PUF PF00806.14 CBK24588.2 - 4.8e-47 154.8 7.8 1.1e-08 34.0 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1397 PF07165.6 CBK24588.2 - 0.02 14.1 3.0 0.058 12.5 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1397) DUF3549 PF12069.3 CBK24588.2 - 0.044 12.5 0.1 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Complex1_LYR PF05347.10 CBK24589.2 - 3.9e-10 39.3 0.5 5.7e-10 38.8 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBK24589.2 - 1.9e-07 31.1 1.1 2.8e-07 30.6 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like WSK PF03832.8 CBK24589.2 - 0.044 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 WSK motif Clathrin PF00637.15 CBK24590.2 - 2.8e-178 584.6 36.7 5.8e-32 110.2 0.0 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CBK24590.2 - 1.6e-20 72.7 1.0 5.9e-20 70.9 0.2 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CBK24590.2 - 4e-13 48.7 0.9 5e-05 23.3 0.0 6.0 7 0 0 7 7 7 2 Clathrin propeller repeat TPR_7 PF13176.1 CBK24590.2 - 0.063 13.1 12.6 16 5.5 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24590.2 - 0.16 11.9 7.8 13 5.8 0.0 5.9 5 1 2 7 7 7 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBK24591.2 - 6.8e-24 83.5 0.0 1.2e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBK24591.2 - 1.8e-08 34.5 0.2 7.5e-08 32.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBK24591.2 - 2.9e-06 27.2 0.1 4.3e-05 23.5 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBK24591.2 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CBK24591.2 - 0.0024 17.4 0.1 0.0083 15.6 0.0 1.7 1 1 1 2 2 2 1 Redoxin tRNA-synt_1b PF00579.20 CBK24592.2 - 1.2e-18 67.3 0.1 6.9e-18 64.7 0.0 2.3 3 1 0 3 3 3 1 tRNA synthetases class I (W and Y) AAA PF00004.24 CBK24593.2 - 1.1e-36 125.9 0.0 1.7e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBK24593.2 - 9.7e-06 25.3 0.4 0.0001 22.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 CBK24593.2 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CBK24593.2 - 8.5e-05 21.7 0.0 0.00019 20.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBK24593.2 - 8.8e-05 22.6 0.9 0.016 15.3 0.5 2.7 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 CBK24593.2 - 0.0016 17.8 0.8 0.43 9.9 0.2 2.3 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 CBK24593.2 - 0.003 16.3 0.1 0.0084 14.8 0.0 1.5 1 1 1 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 CBK24593.2 - 0.0085 16.9 0.1 0.018 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBK24593.2 - 0.0093 15.4 0.6 0.018 14.4 0.4 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBK24593.2 - 0.015 14.8 0.1 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 CBK24593.2 - 0.042 13.6 4.1 0.045 13.4 1.1 2.2 2 1 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 CBK24593.2 - 0.049 12.7 0.2 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBK24593.2 - 0.063 13.2 2.6 0.25 11.3 0.2 2.6 3 1 0 3 3 3 0 AAA ATPase domain AAA_2 PF07724.9 CBK24593.2 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CBK24593.2 - 0.11 12.8 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBK24593.2 - 0.11 12.0 0.7 0.23 11.0 0.1 1.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBK24593.2 - 0.11 12.3 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Ribosomal_S2 PF00318.15 CBK24594.2 - 1.1e-44 152.2 2.7 2.3e-41 141.3 1.8 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 CENP-H PF05837.7 CBK24595.2 - 2.8e-08 33.8 10.9 2.8e-08 33.8 7.6 3.0 1 1 2 3 3 3 1 Centromere protein H (CENP-H) HALZ PF02183.13 CBK24595.2 - 0.011 15.3 3.2 0.011 15.3 2.2 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3511 PF12023.3 CBK24595.2 - 0.091 12.0 0.1 0.28 10.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) OTU PF02338.14 CBK24595.2 - 0.86 10.1 5.1 2.8 8.5 3.3 2.2 1 1 0 1 1 1 0 OTU-like cysteine protease Amidohydro_2 PF04909.9 CBK24596.2 - 3.2e-31 108.9 0.5 3.6e-31 108.7 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.16 CBK24596.2 - 4.7e-05 22.4 0.0 0.0002 20.4 0.0 1.8 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) TraF PF13728.1 CBK24597.2 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein RRM_6 PF14259.1 CBK24598.2 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK24598.2 - 0.00012 21.6 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.2 CBK24598.2 - 0.012 16.1 52.7 0.018 15.5 36.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 CBK24598.2 - 0.021 14.5 36.1 0.036 13.8 25.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RRM_5 PF13893.1 CBK24598.2 - 0.025 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC73 PF05179.9 CBK24598.2 - 0.82 8.9 9.9 0.99 8.6 6.9 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family MIP-T3 PF10243.4 CBK24598.2 - 9.9 4.4 26.5 12 4.1 18.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MORN_2 PF07661.8 CBK24599.2 - 3.1 8.1 7.3 4.4 7.6 0.5 3.3 3 0 0 3 3 3 0 MORN repeat variant Ribosomal_L28 PF00830.14 CBK24600.2 - 3.6e-21 74.7 0.5 5e-21 74.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Peptidase_M3 PF01432.15 CBK24600.2 - 0.0078 15.2 0.0 0.0095 15.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 WD40 PF00400.27 CBK24601.2 - 1e-25 88.5 14.0 9.4e-08 31.6 0.1 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBK24601.2 - 0.0015 18.0 0.5 0.024 14.0 0.1 2.5 1 1 2 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.1 CBK24601.2 - 0.015 15.0 0.0 0.9 9.3 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Gmad1 PF10647.4 CBK24601.2 - 0.049 13.0 0.0 0.13 11.6 0.0 1.9 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK24601.2 - 0.47 10.7 3.8 40 4.6 0.2 4.2 5 0 0 5 5 5 0 PQQ-like domain Pkinase PF00069.20 CBK24602.2 - 4.2e-39 134.2 0.0 6.5e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24602.2 - 1.7e-07 30.5 0.0 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Urocanase PF01175.13 CBK24603.2 - 1.1e-219 730.0 0.2 1.4e-219 729.7 0.1 1.0 1 0 0 1 1 1 1 Urocanase Ldh_1_C PF02866.13 CBK24604.2 - 7.1e-33 113.7 0.0 1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBK24604.2 - 5.7e-29 100.7 0.1 9.5e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MmoB_DmpM PF02406.12 CBK24604.2 - 0.027 14.4 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 MmoB/DmpM family AraC_binding_2 PF14525.1 CBK24604.2 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AraC-binding-like domain NAD_kinase PF01513.16 CBK24604.2 - 0.11 11.2 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase GNT-I PF03071.10 CBK24605.2 - 6.9e-94 314.8 0.2 8e-94 314.6 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Bot1p PF12298.3 CBK24606.2 - 3.6e-05 23.7 0.0 3.6e-05 23.7 0.0 3.0 2 2 1 3 3 3 1 Eukaryotic mitochondrial regulator protein HTH_23 PF13384.1 CBK24606.2 - 0.0011 18.5 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CBK24606.2 - 0.043 13.8 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TRAP_alpha PF03896.11 CBK24606.2 - 0.16 10.9 0.0 0.16 10.9 0.0 3.0 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.1 CBK24606.2 - 0.7 8.8 5.6 1 8.2 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 CBK24606.2 - 1.6 6.9 11.9 2.6 6.2 8.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF874 PF05917.6 CBK24606.2 - 2.1 7.0 11.6 3.7 6.3 8.1 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) CHCH PF06747.8 CBK24607.2 - 9.3e-07 28.6 3.1 9.3e-07 28.6 2.1 2.4 2 1 0 2 2 2 1 CHCH domain Ndufs5 PF10200.4 CBK24607.2 - 0.047 13.6 4.3 0.13 12.2 3.0 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.4 CBK24607.2 - 0.094 12.7 10.7 0.18 11.8 4.6 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CBK24607.2 - 2.2 8.0 12.2 0.51 10.1 2.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Vanabin-2 PF11437.3 CBK24607.2 - 6.4 6.8 10.8 14 5.7 7.5 1.6 1 1 0 1 1 1 0 Vanadium-binding protein 2 LSM PF01423.17 CBK24608.2 - 3e-13 49.1 0.0 3.7e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBK24608.2 - 0.0022 17.8 0.0 0.0029 17.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UCH PF00443.24 CBK24609.2 - 1.3e-19 70.3 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24609.2 - 4e-06 26.4 0.1 3.1e-05 23.5 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FlaC_arch PF05377.6 CBK24609.2 - 0.7 9.8 2.6 0.72 9.7 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-CCCH PF00642.19 CBK24610.2 - 0.00028 20.5 1.8 0.00053 19.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CBK24611.2 - 3e-16 58.7 0.1 7.1e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24611.2 - 4.1e-15 55.5 0.1 1e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24611.2 - 4.8e-12 45.5 0.4 1.1e-11 44.4 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK24611.2 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Vac_Fusion PF02346.11 CBK24612.2 - 0.34 10.3 3.1 0.86 9.0 0.1 3.1 3 1 0 3 3 3 0 Chordopoxvirus fusion protein ABC_tran PF00005.22 CBK24613.2 - 2.5e-73 244.8 0.0 9.9e-38 129.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBK24613.2 - 6.4e-53 179.9 11.0 8.7e-31 107.3 1.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CBK24613.2 - 6.5e-17 62.4 0.3 0.019 14.9 0.0 5.1 4 1 1 5 5 5 4 AAA domain SMC_N PF02463.14 CBK24613.2 - 1.9e-12 46.8 1.0 0.00018 20.8 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBK24613.2 - 3.6e-12 46.6 0.0 1.9e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBK24613.2 - 7.2e-12 45.5 1.3 0.00062 19.9 0.3 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBK24613.2 - 2.7e-09 37.8 0.2 0.0071 17.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CBK24613.2 - 2.8e-09 37.2 0.4 0.00024 21.3 0.0 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBK24613.2 - 4e-09 36.1 1.7 0.11 11.8 0.0 3.7 3 1 0 3 3 3 3 AAA domain DUF258 PF03193.11 CBK24613.2 - 5e-09 35.5 0.0 0.003 16.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK24613.2 - 7.1e-09 35.0 0.3 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBK24613.2 - 1.7e-07 31.0 3.5 0.0032 17.3 0.4 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CBK24613.2 - 2.1e-07 30.7 2.3 0.11 11.8 0.0 4.3 4 0 0 4 4 4 1 AAA-like domain ABC_ATPase PF09818.4 CBK24613.2 - 2.7e-07 29.5 2.7 0.0008 18.0 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 CBK24613.2 - 1.4e-06 28.0 2.5 0.061 12.9 0.0 4.7 4 2 1 5 5 4 2 AAA domain AAA_18 PF13238.1 CBK24613.2 - 1.5e-06 28.5 5.1 0.011 16.0 0.0 4.4 4 1 1 5 5 4 2 AAA domain AAA_5 PF07728.9 CBK24613.2 - 4.4e-06 26.4 0.6 0.66 9.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK24613.2 - 8.3e-06 26.2 8.5 0.018 15.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.15 CBK24613.2 - 3e-05 22.9 4.5 0.039 12.6 0.0 2.7 3 0 0 3 3 2 2 G-protein alpha subunit MobB PF03205.9 CBK24613.2 - 9.7e-05 22.0 0.1 0.68 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 CBK24613.2 - 0.00011 21.3 3.7 0.12 11.3 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 CBK24613.2 - 0.00015 21.7 0.1 0.5 10.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBK24613.2 - 0.0002 21.5 0.0 1 9.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase NB-ARC PF00931.17 CBK24613.2 - 0.00033 19.6 0.1 0.14 10.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 CBK24613.2 - 0.00035 20.4 0.2 0.44 10.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 CBK24613.2 - 0.00076 19.9 0.0 0.62 10.5 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 CBK24613.2 - 0.00078 19.1 0.3 2 8.2 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain Zeta_toxin PF06414.7 CBK24613.2 - 0.00085 18.4 0.0 0.22 10.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.9 CBK24613.2 - 0.00091 18.3 0.1 0.0065 15.4 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain PRK PF00485.13 CBK24613.2 - 0.0021 17.6 0.1 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 CBK24613.2 - 0.0027 16.5 0.0 0.25 10.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_14 PF13173.1 CBK24613.2 - 0.0034 17.2 0.0 3.2 7.6 0.0 3.3 3 1 1 4 4 3 0 AAA domain IstB_IS21 PF01695.12 CBK24613.2 - 0.0038 16.6 0.5 10 5.4 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBK24613.2 - 0.0068 15.8 0.0 4.6 6.6 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad17 PF03215.10 CBK24613.2 - 0.008 14.9 0.0 0.35 9.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 CBK24613.2 - 0.01 15.3 0.5 0.88 9.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CBK24613.2 - 0.011 15.2 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 CBK24613.2 - 0.015 15.0 0.1 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 CBK24613.2 - 0.017 14.0 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CBK24613.2 - 0.02 14.0 0.0 2.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 CBK24613.2 - 0.021 14.6 4.7 0.22 11.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 CBK24613.2 - 0.025 14.2 1.6 6.8 6.3 0.0 3.2 4 0 0 4 4 3 0 NTPase APS_kinase PF01583.15 CBK24613.2 - 0.035 13.7 0.1 3.5 7.2 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.20 CBK24613.2 - 0.042 13.3 0.0 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 CBK24613.2 - 0.052 13.5 0.8 3.3 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 CBK24613.2 - 0.053 12.4 0.2 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Raftlin PF15250.1 CBK24613.2 - 0.099 11.1 2.3 0.16 10.4 1.6 1.2 1 0 0 1 1 1 0 Raftlin SMC_N PF02463.14 CBK24614.2 - 9.5e-16 57.6 0.1 9.8e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBK24614.2 - 1.4e-15 58.1 0.1 1.9e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CBK24614.2 - 6.1e-05 23.1 2.0 0.00074 19.5 0.8 2.0 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 CBK24614.2 - 7.5e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 CBK24614.2 - 0.0002 20.0 0.3 0.00032 19.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CBK24614.2 - 0.0013 17.8 1.4 0.0018 17.3 1.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CBK24614.2 - 0.015 15.5 0.9 0.031 14.5 0.6 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CBK24614.2 - 0.068 13.9 0.9 0.17 12.7 0.6 1.7 1 1 0 1 1 1 0 AAA domain 7TM_GPCR_Srt PF10321.4 CBK24614.2 - 0.075 11.7 0.2 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt MOZ_SAS PF01853.13 CBK24615.2 - 2.1e-76 255.3 1.7 2.8e-76 254.9 1.2 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2_jaz PF12171.3 CBK24615.2 - 0.0038 17.3 1.0 0.0097 16.0 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBK24615.2 - 0.0047 17.1 2.1 0.0067 16.7 0.5 2.1 1 1 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBK24615.2 - 0.029 14.6 2.0 0.047 14.0 0.4 2.2 1 1 0 1 1 1 0 C2H2-type zinc finger GTP_EFTU PF00009.22 CBK24616.2 - 0.00095 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CDC24 PF06395.6 CBK24616.2 - 0.0021 18.0 0.1 0.013 15.5 0.0 2.1 1 1 1 2 2 2 1 CDC24 Calponin DUF4262 PF14081.1 CBK24616.2 - 0.0043 17.1 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) Nop53 PF07767.6 CBK24617.2 - 4e-08 32.6 19.9 4.7e-08 32.4 13.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4613 PF15390.1 CBK24617.2 - 0.087 10.9 6.7 0.1 10.7 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Drc1-Sld2 PF11719.3 CBK24617.2 - 0.15 11.0 12.6 0.18 10.8 8.7 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein FNIP_N PF14636.1 CBK24617.2 - 0.34 11.3 7.5 1.5 9.2 4.9 1.8 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus NAM-associated PF14303.1 CBK24617.2 - 0.92 9.8 19.5 1.1 9.5 13.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain eIF3_subunit PF08597.5 CBK24617.2 - 3.6 7.0 19.0 4.4 6.7 13.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1700 PF08006.6 CBK24617.2 - 4.6 6.5 4.9 6.3 6.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF1770 PF08589.5 CBK24617.2 - 5.1 7.7 6.0 6.2 7.4 0.2 2.1 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) AIG1 PF04548.11 CBK24617.2 - 6.6 5.7 8.6 7.8 5.5 6.0 1.1 1 0 0 1 1 1 0 AIG1 family Nup88 PF10168.4 CBK24617.2 - 6.9 4.3 10.3 7.8 4.2 7.1 1.1 1 0 0 1 1 1 0 Nuclear pore component SprA-related PF12118.3 CBK24617.2 - 7.8 5.7 14.4 9.4 5.4 10.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF4337 PF14235.1 CBK24617.2 - 8.3 6.2 10.9 13 5.5 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Metallophos PF00149.23 CBK24618.2 - 1.9e-23 82.9 0.0 3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.15 CBK24619.2 - 3.7e-58 196.2 6.7 3.7e-58 196.2 4.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK24619.2 - 6.3e-41 139.9 13.0 6.3e-41 139.9 9.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK24619.2 - 8.7e-24 85.1 0.0 7.5e-18 65.7 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK24619.2 - 4.2e-13 49.0 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBK24619.2 - 2.2e-10 41.0 0.0 9.2e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK24619.2 - 0.0058 16.2 0.2 0.12 11.9 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PA14 PF07691.7 CBK24620.2 - 8.9e-16 57.8 4.2 8.9e-09 35.1 0.1 2.6 2 0 0 2 2 2 2 PA14 domain He_PIG PF05345.7 CBK24620.2 - 1.5e-12 47.3 17.6 2.9e-05 23.9 0.5 5.3 5 0 0 5 5 5 3 Putative Ig domain He_PIG PF05345.7 CBK24621.2 - 9e-06 25.6 0.8 1.5e-05 24.9 0.6 1.3 1 0 0 1 1 1 1 Putative Ig domain Med31 PF05669.7 CBK24622.2 - 1.7e-33 114.4 8.9 2.1e-33 114.1 6.2 1.1 1 0 0 1 1 1 1 SOH1 Ribosomal_S19e PF01090.14 CBK24623.2 - 1.8e-34 118.1 0.0 2e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HrcA_DNA-bdg PF03444.10 CBK24623.2 - 0.046 13.1 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ribosomal_L40e PF01020.12 CBK24624.2 - 9.8e-32 108.3 13.7 1.7e-31 107.5 9.5 1.4 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBK24624.2 - 9.9e-18 63.3 0.0 1.3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK24624.2 - 5.2e-11 42.0 0.4 7.4e-11 41.5 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK24624.2 - 0.025 14.7 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF866 PF05907.8 CBK24625.2 - 3.8e-24 85.0 4.2 8.9e-23 80.5 2.9 2.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_4 PF13717.1 CBK24625.2 - 0.28 10.8 6.3 0.41 10.3 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK24625.2 - 0.48 10.0 6.2 0.56 9.8 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CBK24625.2 - 4.6 7.1 7.8 22 4.9 5.4 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ribonuc_red_lgC PF02867.10 CBK24626.2 - 2.7e-08 32.8 0.0 0.0002 20.0 0.0 3.1 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBK24626.2 - 0.14 11.9 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Glycos_transf_1 PF00534.15 CBK24627.2 - 8.8e-13 48.0 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBK24627.2 - 2.3e-05 24.5 0.0 5.9e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBK24627.2 - 0.0092 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3135 PF11333.3 CBK24627.2 - 0.013 15.6 0.3 0.025 14.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Pkinase PF00069.20 CBK24628.2 - 2.7e-19 69.3 0.0 3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24628.2 - 6.1e-10 38.5 0.0 6.7e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FKBP_C PF00254.23 CBK24629.2 - 6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PH_3 PF14593.1 CBK24629.2 - 0.003 17.4 0.0 0.0078 16.0 0.0 1.6 1 1 0 1 1 1 1 PH domain Glyco_transf_49 PF13896.1 CBK24630.2 - 9.6e-07 28.1 0.2 0.017 14.2 0.0 2.4 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan Adap_comp_sub PF00928.16 CBK24631.2 - 2.5e-36 125.1 0.0 3.4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK24631.2 - 1.9e-06 27.6 0.3 2.9e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_8 PF13855.1 CBK24632.2 - 2.5e-05 23.9 6.1 0.095 12.4 0.0 4.7 3 2 1 4 4 4 3 Leucine rich repeat hSac2 PF12456.3 CBK24632.2 - 0.00021 20.6 4.7 11 5.3 0.0 5.2 3 1 2 5 5 5 2 Inositol phosphatase LRR_4 PF12799.2 CBK24632.2 - 0.021 14.4 3.1 3.4 7.3 0.1 4.2 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Trypan_PARP PF05887.6 CBK24632.2 - 0.084 12.6 1.3 0.14 11.9 0.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SVS_QK PF10578.4 CBK24632.2 - 2.6 8.6 5.7 2.8 8.5 1.2 3.0 2 0 0 2 2 2 0 Seminal vesicle protein repeat NESP55 PF06390.7 CBK24632.2 - 8 5.7 7.3 12 5.1 5.1 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) HEAT_2 PF13646.1 CBK24635.2 - 3.4e-16 59.3 22.7 2.9e-05 24.2 0.0 8.4 7 4 1 8 8 8 4 HEAT repeats HEAT PF02985.17 CBK24635.2 - 9e-10 37.8 13.1 0.00078 19.3 0.0 10.6 13 0 0 13 13 11 2 HEAT repeat ParcG PF10274.4 CBK24635.2 - 7.7e-07 29.1 1.3 0.033 14.0 0.0 4.0 4 0 0 4 4 4 2 Parkin co-regulated protein IBN_N PF03810.14 CBK24635.2 - 7.3e-05 22.6 8.8 0.0087 15.9 0.4 5.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain DUF3385 PF11865.3 CBK24635.2 - 0.00076 19.4 11.1 0.91 9.4 0.0 6.4 7 0 0 7 7 7 2 Domain of unknown function (DUF3385) DUF3384 PF11864.3 CBK24635.2 - 0.002 16.7 2.7 0.0084 14.6 0.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) HEAT_EZ PF13513.1 CBK24635.2 - 0.0043 17.5 22.3 5.2 7.6 0.0 10.2 8 4 5 13 13 13 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CBK24635.2 - 0.0045 17.3 1.0 2.3 8.6 0.0 4.6 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.9 CBK24635.2 - 0.03 13.4 6.9 0.075 12.1 0.6 3.8 4 1 1 5 5 5 0 V-ATPase subunit H HEAT_PBS PF03130.11 CBK24635.2 - 0.2 12.2 3.0 18 6.1 0.0 5.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 CBK24635.2 - 0.3 10.9 5.8 13 5.5 0.0 4.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBK24635.2 - 0.75 9.7 11.0 18 5.3 0.0 6.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat RNase_PH PF01138.16 CBK24636.2 - 1.5e-15 57.6 0.0 2.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBK24636.2 - 0.0023 17.8 0.1 0.007 16.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Ribosomal_S24e PF01282.14 CBK24637.2 - 1.6e-27 95.1 0.0 2.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e CAS_CSE1 PF03378.10 CBK24638.2 - 2.4e-13 49.2 0.1 3e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Utp13 PF08625.6 CBK24638.2 - 0.082 12.5 0.2 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF2813 PF11398.3 CBK24640.2 - 0.15 11.1 0.4 0.17 10.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Mitofilin PF09731.4 CBK24642.2 - 0.0058 15.3 31.4 0.044 12.4 21.7 2.6 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Unstab_antitox PF09720.5 CBK24642.2 - 0.014 15.0 2.4 0.014 15.0 1.7 3.2 3 0 0 3 3 3 0 Putative addiction module component ORC3_N PF07034.6 CBK24642.2 - 1.1 8.1 9.5 0.6 9.0 3.1 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus PPR_2 PF13041.1 CBK24643.2 - 4.3e-44 148.2 8.7 1.5e-08 34.5 0.1 9.1 5 2 5 10 10 10 8 PPR repeat family PPR_3 PF13812.1 CBK24643.2 - 7.7e-35 116.2 5.6 5e-05 23.2 0.0 10.5 10 0 0 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.15 CBK24643.2 - 3e-32 108.3 9.9 0.00045 20.0 0.0 8.9 9 0 0 9 9 9 7 PPR repeat PPR_1 PF12854.2 CBK24643.2 - 1.5e-17 62.7 3.2 0.0081 15.6 0.0 8.6 10 1 0 10 10 10 5 PPR repeat TPR_14 PF13428.1 CBK24643.2 - 8.7e-05 22.8 0.3 5.6 7.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK24643.2 - 9.3e-05 22.6 0.0 0.99 9.7 0.0 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.15 CBK24643.2 - 0.0011 18.6 0.2 0.17 11.4 0.0 3.7 3 1 1 4 4 4 1 Region in Clathrin and VPS Sulfotransfer_1 PF00685.22 CBK24643.2 - 0.013 14.7 0.1 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain MRP-S27 PF10037.4 CBK24643.2 - 0.032 13.1 0.3 0.067 12.1 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.2 CBK24643.2 - 0.097 12.0 0.0 13 5.1 0.0 3.1 2 2 0 2 2 2 0 Mitochondrial ATPase expression Y_phosphatase2 PF03162.8 CBK24644.2 - 2e-36 124.8 0.0 2.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBK24644.2 - 0.0021 17.4 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBK24644.2 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family RRM_1 PF00076.17 CBK24645.2 - 2.3e-12 46.3 0.1 8e-11 41.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24645.2 - 3.9e-11 42.7 0.0 1.2e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBK24645.2 - 2.5e-06 27.4 0.0 6.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 CBK24645.2 - 4.8e-05 23.1 0.0 9.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A3L PF05288.6 CBK24645.2 - 0.011 15.4 0.2 0.034 13.8 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A3L Protein Spo7_2_N PF15407.1 CBK24645.2 - 0.027 13.9 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 Sporulation protein family 7 Sin3_corepress PF08295.7 CBK24646.2 - 1.8e-29 101.4 0.0 3.7e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor TFIIE-A_C-term PF11521.3 CBK24646.2 - 0.82 9.6 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ribosomal_60s PF00428.14 CBK24646.2 - 9.3 6.7 11.1 2.7 8.4 5.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HSP70 PF00012.15 CBK24647.2 - 6.2e-276 916.1 7.0 7e-276 915.9 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24647.2 - 7.6e-20 70.7 0.3 1.3e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CBK24647.2 - 0.00011 21.3 0.2 0.02 14.0 0.0 2.5 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase DDR PF08841.5 CBK24647.2 - 0.00055 18.8 0.2 0.014 14.2 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 CBK24647.2 - 0.00069 19.4 0.4 0.065 13.0 0.0 3.4 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 CBK24647.2 - 0.028 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CBK24647.2 - 0.042 13.1 0.1 8.9 5.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Carboxyl_trans PF01039.17 CBK24649.2 - 6.8e-191 634.8 0.1 8.1e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK24649.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Kin17_mid PF10357.4 CBK24650.2 - 2.6e-40 136.9 2.1 2.6e-40 136.9 1.5 2.3 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CBK24650.2 - 0.47 10.7 2.5 1.1 9.5 1.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PGA2 PF07543.7 CBK24650.2 - 5.7 6.7 14.6 3.3 7.5 5.8 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 IP_trans PF02121.13 CBK24652.2 - 7.3e-38 130.1 0.1 1.5e-37 129.1 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein EamA PF00892.15 CBK24652.2 - 2.5e-05 24.2 3.5 2.5e-05 24.2 2.4 3.8 4 0 0 4 4 4 1 EamA-like transporter family EmrE PF13536.1 CBK24652.2 - 0.0013 18.9 11.3 0.0063 16.7 0.7 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EcsC PF12787.2 CBK24652.2 - 0.045 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 EcsC protein family Col_cuticle_N PF01484.12 CBK24652.2 - 0.073 12.7 1.4 0.48 10.1 1.0 2.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain LRR_8 PF13855.1 CBK24654.2 - 0.021 14.5 0.2 0.41 10.4 0.1 2.2 1 1 1 2 2 2 0 Leucine rich repeat hSac2 PF12456.3 CBK24654.2 - 0.047 13.0 0.2 0.68 9.3 0.0 2.3 1 1 2 3 3 3 0 Inositol phosphatase Tim17 PF02466.14 CBK24655.2 - 3.4e-26 91.7 0.7 5.3e-26 91.1 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oxysterol_BP PF01237.13 CBK24656.2 - 3.5e-69 232.9 0.0 4.6e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein gag-asp_proteas PF13975.1 CBK24656.2 - 0.092 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PRA1 PF03208.14 CBK24657.2 - 9.1e-19 67.3 9.8 1.1e-18 67.0 6.8 1.1 1 0 0 1 1 1 1 PRA1 family protein UBX PF00789.15 CBK24658.2 - 5.2e-05 23.2 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain DUF4520 PF15016.1 CBK24659.2 - 0.078 12.5 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF3650 PF12368.3 CBK24659.2 - 0.15 11.6 0.1 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) ROK PF00480.15 CBK24660.2 - 4.3e-41 140.7 2.8 5.3e-41 140.4 1.9 1.1 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.15 CBK24660.2 - 8.6e-08 31.8 0.5 1.1e-07 31.4 0.4 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.16 CBK24660.2 - 2.8e-05 23.5 0.0 5.2e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L22 PF00237.14 CBK24661.2 - 4.5e-29 100.4 0.1 6.8e-29 99.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e tRNA_m1G_MT PF01746.16 CBK24662.2 - 1.3e-22 80.3 0.0 3.1e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase dsrm PF00035.20 CBK24662.2 - 4.8e-05 23.8 2.3 0.00019 21.9 1.6 2.0 1 1 0 1 1 1 1 Double-stranded RNA binding motif NUDIX PF00293.23 CBK24663.2 - 6.3e-24 84.1 0.0 7.8e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TRAP-gamma PF07074.7 CBK24664.2 - 9.2e-06 25.2 9.4 0.0012 18.4 2.4 2.1 1 1 1 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) PrgI PF12666.2 CBK24664.2 - 0.052 13.7 3.6 0.058 13.5 0.0 2.2 2 0 0 2 2 2 0 PrgI family protein DUF4118 PF13493.1 CBK24664.2 - 7.9 6.7 14.1 9.1 6.5 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) PDR_assoc PF08370.6 CBK24666.2 - 0.074 12.5 0.2 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Viral_Beta_CD PF04530.7 CBK24666.2 - 0.088 12.9 0.1 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Viral Beta C/D like family FYVE PF01363.16 CBK24667.2 - 8.8e-18 63.9 17.0 8.8e-18 63.9 11.8 2.1 2 1 0 2 2 2 1 FYVE zinc finger MEDS PF14417.1 CBK24667.2 - 0.14 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ATP-synt_ab PF00006.20 CBK24668.2 - 3.7e-60 203.0 0.0 5e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK24668.2 - 5.2e-13 49.4 0.0 9.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK24668.2 - 3e-10 40.1 0.5 5.4e-10 39.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBK24668.2 - 0.0033 17.2 0.1 0.0074 16.1 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain PTS-HPr PF00381.14 CBK24669.2 - 0.018 14.9 0.0 0.018 14.8 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site Pro_isomerase PF00160.16 CBK24670.2 - 1.1e-35 123.1 0.1 1.7e-35 122.4 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prp19_bind PF06991.6 CBK24671.2 - 1.4e-39 136.0 24.2 1.6e-39 135.9 16.8 1.0 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain CDC45 PF02724.9 CBK24671.2 - 0.87 7.5 18.8 1 7.2 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.1 CBK24671.2 - 6.6 6.9 8.4 1.6 8.9 3.1 1.9 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CorA PF01544.13 CBK24673.2 - 1.1e-14 54.2 1.7 1.2e-14 54.1 1.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3533 PF12051.3 CBK24673.2 - 0.051 12.3 2.4 0.063 12.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Mem_trans PF03547.13 CBK24673.2 - 0.23 9.7 1.6 0.27 9.4 1.1 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2101 PF09874.4 CBK24673.2 - 0.71 9.3 6.7 0.95 8.9 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) YbgT_YccB PF08173.6 CBK24673.2 - 2.3 8.1 5.4 4.5 7.1 3.8 1.5 1 0 0 1 1 1 0 Membrane bound YbgT-like protein DUF947 PF06102.7 CBK24674.2 - 9.1e-38 129.7 39.2 1e-37 129.5 27.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF947) RRM_1 PF00076.17 CBK24675.2 - 1.8e-07 30.7 0.3 3.9e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med20 PF08612.6 CBK24675.2 - 0.00018 20.7 0.1 0.00045 19.4 0.1 1.6 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RRM_6 PF14259.1 CBK24675.2 - 0.00024 21.0 0.2 0.00073 19.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24675.2 - 0.013 15.2 0.1 0.013 15.2 0.1 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK24675.2 - 0.015 15.1 0.1 0.015 15.1 0.1 2.5 2 1 0 2 2 2 0 RNA binding motif RTC4 PF14474.1 CBK24675.2 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 RTC4-like domain Nup35_RRM_2 PF14605.1 CBK24675.2 - 0.07 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Borrelia_P83 PF05262.6 CBK24675.2 - 0.18 10.0 6.8 0.23 9.7 4.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC50 PF03381.10 CBK24676.2 - 2.5e-45 154.8 0.1 2.9e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Toxin_YhaV PF11663.3 CBK24676.2 - 0.046 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Toxin with endonuclease activity YhaV He_PIG PF05345.7 CBK24678.2 - 7.3e-07 29.1 0.2 1.9e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Putative Ig domain Protocadherin PF08374.6 CBK24678.2 - 0.0036 16.9 2.6 0.0053 16.4 1.8 1.2 1 0 0 1 1 1 1 Protocadherin DUF912 PF06024.7 CBK24678.2 - 0.013 15.5 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) P12 PF12669.2 CBK24678.2 - 0.033 14.3 2.7 0.083 13.1 1.9 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family ASFV_J13L PF05568.6 CBK24678.2 - 0.037 13.5 0.9 0.074 12.5 0.6 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Endomucin PF07010.7 CBK24678.2 - 0.051 12.8 0.6 0.08 12.2 0.4 1.2 1 0 0 1 1 1 0 Endomucin Shisa PF13908.1 CBK24678.2 - 0.093 12.9 0.7 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HemY_N PF07219.8 CBK24678.2 - 0.1 12.1 0.9 0.16 11.5 0.6 1.2 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.1 CBK24678.2 - 0.14 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 CBK24678.2 - 0.16 12.4 1.6 0.29 11.5 1.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CBK24678.2 - 0.29 10.7 3.9 0.46 10.0 2.7 1.2 1 0 0 1 1 1 0 Rifin/stevor family ETF PF01012.16 CBK24679.2 - 6.3e-33 113.8 0.1 7.7e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ADH_zinc_N PF00107.21 CBK24679.2 - 0.098 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3895 PF13034.1 CBK24679.2 - 0.1 12.0 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) DUF4383 PF14325.1 CBK24680.2 - 0.048 13.6 0.6 0.048 13.6 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) Fun_ATP-synt_8 PF05933.8 CBK24681.2 - 3 7.9 7.9 0.65 10.0 3.0 1.7 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) zf-Tim10_DDP PF02953.10 CBK24682.2 - 3.9e-12 45.2 5.2 4.8e-12 44.9 3.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.22 CBK24683.2 - 1.4e-78 258.7 3.7 2.9e-26 91.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HAP PF03866.8 CBK24683.2 - 0.057 13.1 0.3 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) UCR_Fe-S_N PF10399.4 CBK24683.2 - 0.41 9.8 4.4 0.1 11.7 0.7 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_transf_92 PF01697.22 CBK24685.2 - 3.6e-13 49.4 4.5 3.6e-13 49.4 3.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 CBK24685.2 - 1.4e-05 25.3 0.2 5.6e-05 23.3 0.1 2.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 TatD_DNase PF01026.16 CBK24686.2 - 3.9e-46 157.3 0.0 4.4e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase zf-Mss51 PF13824.1 CBK24686.2 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PX PF00787.19 CBK24687.2 - 3.3e-22 78.4 0.2 5.6e-22 77.6 0.2 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CBK24687.2 - 1.8e-09 37.2 7.8 3.3e-09 36.3 5.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like EF-hand_4 PF12763.2 CBK24687.2 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 CBK24687.2 - 0.0088 15.8 1.1 0.03 14.1 0.8 2.0 1 0 0 1 1 1 1 EF-hand domain Mt_ATP-synt_B PF05405.9 CBK24687.2 - 0.083 12.3 2.8 0.3 10.5 2.0 1.9 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_B PF00430.13 CBK24687.2 - 0.14 12.0 14.0 0.018 14.8 6.2 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Adap_comp_sub PF00928.16 CBK24688.2 - 1.7e-43 148.6 0.1 2.3e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK24688.2 - 5e-05 23.0 0.1 8.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Baculo_gp41 PF04700.7 CBK24688.2 - 0.012 15.0 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DisA-linker PF10635.4 CBK24688.2 - 0.024 14.1 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region DUF1391 PF07151.7 CBK24688.2 - 0.16 11.5 0.4 0.3 10.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Peptidase_M24 PF00557.19 CBK24689.2 - 8.7e-26 90.7 0.1 8.7e-26 90.7 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 NodZ PF05830.6 CBK24690.2 - 0.06 11.9 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) tRNA-synt_2 PF00152.15 CBK24691.2 - 1.6e-89 300.0 0.0 2.4e-89 299.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBK24691.2 - 1.4e-13 50.4 0.1 2.9e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBK24691.2 - 1.6e-07 30.7 0.0 0.0034 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UCH PF00443.24 CBK24692.2 - 3.2e-24 85.4 0.0 4.9e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK24692.2 - 3.6e-07 29.9 0.0 9.5e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SYF2 PF08231.7 CBK24693.2 - 4.9e-29 101.4 13.2 5.6e-29 101.2 9.2 1.0 1 0 0 1 1 1 1 SYF2 splicing factor DUF2963 PF11178.3 CBK24693.2 - 0.073 12.5 1.5 0.14 11.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) CmcH_NodU PF02543.10 CBK24693.2 - 0.18 10.8 0.9 0.21 10.7 0.6 1.1 1 0 0 1 1 1 0 Carbamoyltransferase DUF4298 PF14131.1 CBK24693.2 - 0.45 10.4 3.3 2.6 7.9 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) tRNA-synt_1b PF00579.20 CBK24694.2 - 1.1e-35 123.2 0.1 1.4e-35 122.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1762 PF08574.5 CBK24694.2 - 0.015 15.7 0.4 0.78 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1762) MT-A70 PF05063.9 CBK24695.2 - 1.9e-34 118.7 0.0 2.3e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 MT-A70 4HBT PF03061.17 CBK24696.2 - 0.00016 21.7 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Rpr2 PF04032.11 CBK24699.2 - 0.038 13.8 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribophorin_II PF05817.9 CBK24700.2 - 2.3e-12 45.9 0.0 3.3e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Cadherin-like PF12733.2 CBK24700.2 - 0.034 14.4 0.0 0.17 12.2 0.0 1.9 1 1 1 2 2 2 0 Cadherin-like beta sandwich domain RabGAP-TBC PF00566.13 CBK24701.2 - 5.4e-34 117.5 0.0 7.3e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4085 PF13315.1 CBK24701.2 - 0.094 12.0 0.0 5.9 6.1 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4085) SpoIISA_toxin PF14171.1 CBK24702.2 - 0.0022 17.2 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system Bap31 PF05529.7 CBK24702.2 - 0.0043 16.5 3.0 0.0092 15.4 2.1 1.6 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF968 PF06147.6 CBK24702.2 - 0.055 13.3 1.5 0.08 12.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF968) 2TM PF13239.1 CBK24702.2 - 0.13 12.3 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 2TM domain OAD_gamma PF04277.8 CBK24702.2 - 0.16 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ubiquitin PF00240.18 CBK24703.2 - 1.3e-16 59.6 0.4 2.9e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family MBT PF02820.13 CBK24703.2 - 2.6e-06 27.2 0.1 5.4e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 mbt repeat Rad60-SLD PF11976.3 CBK24703.2 - 2.4e-05 23.9 0.1 4.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Tudor-knot PF11717.3 CBK24703.2 - 0.00077 19.1 1.8 0.0021 17.7 1.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Rad60-SLD_2 PF13881.1 CBK24703.2 - 0.0039 17.0 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBK24703.2 - 0.013 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 CBK24703.2 - 0.046 13.9 0.1 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Metallophos PF00149.23 CBK24704.2 - 1.1e-42 145.7 0.3 1.3e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase REV PF00424.13 CBK24705.2 - 0.47 10.3 3.9 0.44 10.4 0.3 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Macoilin PF09726.4 CBK24705.2 - 0.85 7.8 25.6 0.9 7.7 17.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 CBK24705.2 - 0.86 7.2 27.2 1.1 6.8 18.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S4 PF00163.14 CBK24706.2 - 3.6e-20 72.1 0.4 7.2e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBK24706.2 - 6.3e-13 47.9 0.4 6.3e-13 47.9 0.3 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.7 CBK24706.2 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger Phospholip_B PF04916.8 CBK24707.2 - 4.2e-142 474.0 1.1 5.5e-142 473.6 0.8 1.0 1 0 0 1 1 1 1 Phospholipase B Pkinase PF00069.20 CBK24708.2 - 8.6e-69 231.5 0.0 8.6e-69 231.5 0.0 2.0 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24708.2 - 1.3e-41 142.4 0.0 3e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Not3 PF04065.10 CBK24708.2 - 9.7e-40 136.2 26.5 1.7e-39 135.5 18.4 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Kinase-like PF14531.1 CBK24708.2 - 0.00021 20.3 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Snapin_Pallidin PF14712.1 CBK24708.2 - 0.00089 19.5 6.5 0.00089 19.5 4.5 2.9 2 1 0 2 2 2 1 Snapin/Pallidin Baculo_PEP_C PF04513.7 CBK24708.2 - 0.0076 16.0 1.7 0.15 11.8 0.2 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 CBK24708.2 - 0.07 12.0 13.5 0.11 11.4 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YrbL-PhoP_reg PF10707.4 CBK24708.2 - 0.12 11.7 0.1 0.12 11.7 0.0 2.7 3 1 0 3 3 2 0 PhoP regulatory network protein YrbL DUF2203 PF09969.4 CBK24708.2 - 0.19 11.9 13.2 0.05 13.8 1.5 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 CBK24708.2 - 0.5 10.1 15.1 0.94 9.2 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.3 CBK24708.2 - 0.96 9.4 27.7 2.5 8.1 6.1 2.5 2 0 0 2 2 2 0 YlqD protein DUF3584 PF12128.3 CBK24708.2 - 1.4 6.1 24.7 2 5.6 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 CBK24708.2 - 1.7 8.9 9.3 1 9.6 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 CBK24708.2 - 1.8 8.9 17.6 0.67 10.3 5.0 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.1 CBK24708.2 - 3.5 7.6 32.8 70 3.4 9.2 2.8 1 1 1 2 2 2 0 FlxA-like protein DUF3573 PF12097.3 CBK24708.2 - 4.3 5.8 17.7 0.72 8.4 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF3450 PF11932.3 CBK24708.2 - 5 6.3 18.5 0.23 10.7 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.10 CBK24708.2 - 7.2 5.7 14.5 13 4.8 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4164 PF13747.1 CBK24708.2 - 7.6 6.7 14.1 3.5 7.8 2.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.8 CBK24708.2 - 7.8 5.4 23.5 4.9 6.1 4.8 2.3 1 1 1 2 2 2 0 TMPIT-like protein PAP_central PF04928.12 CBK24709.2 - 5.4e-25 87.6 0.0 8.3e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBK24709.2 - 6.9e-14 51.6 3.9 9.9e-14 51.1 0.1 2.6 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain DUF4576 PF15144.1 CBK24709.2 - 0.018 14.6 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) DUF3895 PF13034.1 CBK24709.2 - 0.12 11.9 0.1 0.58 9.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) EMP70 PF02990.11 CBK24710.2 - 2.2e-85 287.0 26.2 3e-85 286.6 18.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.11 CBK24711.2 - 2.8e-15 55.7 0.0 3.4e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF563 PF04577.9 CBK24712.2 - 1.6e-22 80.4 0.2 4.1e-22 79.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF3142 PF11340.3 CBK24712.2 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) TAFII55_N PF04658.8 CBK24713.2 - 1.4e-17 63.6 0.0 4.3e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 TAFII55 protein conserved region Cyclin PF08613.6 CBK24714.2 - 2.3e-24 86.4 1.5 2.9e-24 86.1 1.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBK24714.2 - 1.2e-11 44.2 0.8 1.6e-11 43.8 0.6 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CAP_C PF08603.6 CBK24716.2 - 6.2e-46 155.6 8.8 9e-46 155.1 6.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 CBK24716.2 - 1.7e-34 119.5 4.6 3.2e-34 118.6 3.2 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 CBK24716.2 - 0.0081 15.5 9.0 0.017 14.5 5.8 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C NUDIX PF00293.23 CBK24717.2 - 2.3e-18 66.1 0.1 3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Glucosamine_iso PF01182.15 CBK24718.2 - 5.4e-20 71.9 0.0 8.8e-20 71.2 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Viral_env_E26 PF11050.3 CBK24719.2 - 0.024 13.8 0.0 0.056 12.6 0.0 1.6 2 0 0 2 2 2 0 Virus envelope protein E26 Peptidase_M22 PF00814.20 CBK24720.2 - 7.7e-49 166.5 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Na_Ca_ex PF01699.19 CBK24721.2 - 1.8e-19 69.7 10.7 1.8e-19 69.7 7.4 1.8 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DUF788 PF05620.6 CBK24721.2 - 0.0027 17.6 0.2 0.0027 17.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF788) DUF4519 PF15012.1 CBK24721.2 - 0.13 12.1 0.3 0.13 12.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Na_Ca_ex PF01699.19 CBK24722.2 - 5e-22 78.0 7.8 5e-22 78.0 5.4 2.2 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DUF3432 PF11914.3 CBK24722.2 - 0.91 9.5 10.3 1.1 9.2 6.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DUF572 PF04502.8 CBK24722.2 - 2.7 7.1 4.7 3.9 6.6 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4131 PF13567.1 CBK24722.2 - 4.8 6.5 13.8 0.18 11.2 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ras PF00071.17 CBK24723.2 - 1e-54 184.3 0.3 1.5e-54 183.7 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBK24723.2 - 6.8e-18 65.2 0.0 8e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBK24723.2 - 3e-14 52.6 0.0 4.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBK24723.2 - 1.1e-06 28.6 0.2 1e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK24723.2 - 1.7e-05 24.0 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DCX PF03607.12 CBK24723.2 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Doublecortin GTP_EFTU PF00009.22 CBK24723.2 - 0.00043 19.7 0.1 0.0022 17.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBK24723.2 - 0.011 14.9 0.2 0.11 11.7 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF3354 PF11834.3 CBK24723.2 - 0.028 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) SRP19 PF01922.12 CBK24724.2 - 3.4e-24 85.2 0.0 4.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein zf-primase PF09329.6 CBK24724.2 - 0.1 12.2 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Primase zinc finger DUF1399 PF07173.7 CBK24725.2 - 0.0086 16.3 0.4 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1399) UPF0020 PF01170.13 CBK24725.2 - 0.067 12.7 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 NPCC PF08058.6 CBK24725.2 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore complex component Sec1 PF00995.18 CBK24726.2 - 5.3e-84 282.8 0.0 6e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Evr1_Alr PF04777.8 CBK24728.2 - 2.2e-27 94.7 3.5 2.2e-27 94.7 2.4 1.7 2 0 0 2 2 2 1 Erv1 / Alr family SfsA PF03749.8 CBK24728.2 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 1 0 1 1 1 0 Sugar fermentation stimulation protein LmjF365940-deam PF14421.1 CBK24728.2 - 0.047 13.0 0.0 0.083 12.2 0.0 1.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Fe-ADH PF00465.14 CBK24729.2 - 5.5e-79 265.4 0.1 6.3e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK24729.2 - 1.3e-11 44.2 0.1 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase E1-E2_ATPase PF00122.15 CBK24730.2 - 4.4e-65 218.9 2.1 8.6e-65 217.9 1.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBK24730.2 - 4.9e-40 136.9 2.0 1.5e-21 76.7 0.0 3.5 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBK24730.2 - 2.4e-30 106.5 0.0 2.5e-29 103.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK24730.2 - 1.3e-23 82.7 0.0 3e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBK24730.2 - 2.1e-16 59.1 0.0 3.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBK24730.2 - 7.3e-12 45.8 0.0 3e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBK24730.2 - 0.0011 18.6 1.0 0.022 14.3 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK24730.2 - 0.17 12.0 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Asp_protease PF09668.5 CBK24730.2 - 0.6 9.6 3.4 0.35 10.4 0.1 2.2 3 0 0 3 3 3 0 Aspartyl protease PepSY_TM_3 PF13706.1 CBK24730.2 - 2.4 7.6 5.8 1.3 8.4 0.1 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix Snf7 PF03357.16 CBK24731.2 - 1.2e-22 80.1 21.6 1.4e-22 79.8 14.9 1.1 1 0 0 1 1 1 1 Snf7 Sec34 PF04136.10 CBK24731.2 - 0.0021 17.7 10.0 0.034 13.8 0.8 2.4 1 1 1 2 2 2 2 Sec34-like family Ribosomal_L29 PF00831.18 CBK24731.2 - 0.049 13.3 3.0 0.21 11.2 0.2 2.7 2 0 0 2 2 2 0 Ribosomal L29 protein NPV_P10 PF05531.7 CBK24731.2 - 0.06 13.5 6.5 2.7 8.2 0.4 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Macoilin PF09726.4 CBK24731.2 - 0.13 10.5 8.5 0.15 10.2 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Nup54 PF13874.1 CBK24731.2 - 0.15 11.7 9.5 0.021 14.4 2.9 2.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Tex_N PF09371.5 CBK24731.2 - 0.17 11.2 5.2 2.6 7.3 0.1 2.9 2 1 1 3 3 3 0 Tex-like protein N-terminal domain Syntaxin-6_N PF09177.6 CBK24731.2 - 0.17 12.3 3.5 8.4 6.8 0.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2450 PF10475.4 CBK24731.2 - 0.29 10.0 9.7 0.38 9.6 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CBK24731.2 - 0.3 10.9 10.5 0.11 12.3 1.7 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 CBK24731.2 - 0.31 10.1 5.3 0.92 8.6 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V-ATPase_C PF03223.10 CBK24731.2 - 0.31 9.8 10.9 1.3 7.8 2.1 2.1 1 1 1 2 2 2 0 V-ATPase subunit C CENP-F_leu_zip PF10473.4 CBK24731.2 - 0.56 10.0 13.0 0.36 10.7 1.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 CBK24731.2 - 1.2 8.9 9.4 0.2 11.5 3.1 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.15 CBK24731.2 - 1.3 8.8 14.4 1.3 8.8 0.3 3.7 3 2 0 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.2 CBK24731.2 - 1.7 8.4 10.8 7.2 6.4 1.6 2.3 1 1 1 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 CBK24731.2 - 1.8 8.3 8.3 2 8.2 2.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KLRAQ PF10205.4 CBK24731.2 - 2 8.4 7.8 3.5 7.7 1.7 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 CBK24731.2 - 2.4 7.1 12.5 0.25 10.3 1.2 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 CBK24731.2 - 2.5 7.8 7.9 1.4 8.6 1.9 2.4 1 1 1 2 2 2 0 Laminin Domain II ECM11 PF15463.1 CBK24731.2 - 3.9 7.7 12.0 1.6 9.0 0.6 3.2 2 1 1 3 3 3 0 Extracellular mutant protein 11 DUF342 PF03961.8 CBK24731.2 - 4.5 5.5 9.5 3.5 5.9 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Beta_helix PF13229.1 CBK24732.2 - 4.7e-08 32.9 12.8 6.7e-06 25.9 6.9 2.4 1 1 1 2 2 2 2 Right handed beta helix region PAN_4 PF14295.1 CBK24732.2 - 5.7e-05 22.7 0.3 0.00013 21.5 0.2 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CBK24732.2 - 7.2e-05 22.4 0.1 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 PAN domain NosD PF05048.8 CBK24732.2 - 0.00048 19.3 6.2 0.00083 18.5 4.3 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 CBK24732.2 - 0.0013 17.9 2.9 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1565) MANEC PF07502.9 CBK24732.2 - 0.03 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 MANEC domain ABC_tran PF00005.22 CBK24733.2 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF563 PF04577.9 CBK24734.2 - 6e-23 81.8 0.3 1.1e-22 80.9 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Rhomboid PF01694.17 CBK24735.2 - 9.2e-08 32.2 10.0 9.2e-08 32.2 6.9 3.0 3 1 0 3 3 3 1 Rhomboid family LIM PF00412.17 CBK24736.2 - 1.1e-24 86.2 24.6 5.1e-14 52.0 5.7 2.7 2 0 0 2 2 2 2 LIM domain CH PF00307.26 CBK24736.2 - 1.8e-09 37.6 0.0 4.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Tudor-knot PF11717.3 CBK24736.2 - 0.14 11.8 0.3 0.3 10.8 0.2 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DZR PF12773.2 CBK24736.2 - 0.91 9.3 23.5 5 7.0 1.0 4.7 1 1 2 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CBK24736.2 - 2.2 8.2 22.7 21 5.1 3.4 4.8 4 1 0 4 4 4 0 Zinc ribbon domain Proteasome PF00227.21 CBK24737.2 - 5.4e-52 175.8 0.1 7e-52 175.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK24737.2 - 3.6e-11 42.1 0.0 6.9e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Yae1_N PF09811.4 CBK24737.2 - 1e-06 28.1 17.5 0.00066 19.1 12.1 2.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SICA_C PF12879.2 CBK24737.2 - 0.031 14.1 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain Sugarporin_N PF11471.3 CBK24738.2 - 0.0095 15.5 0.0 0.065 12.8 0.0 2.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension RPEL PF02755.10 CBK24738.2 - 0.041 13.2 7.4 0.58 9.5 0.2 3.7 3 0 0 3 3 3 0 RPEL repeat DUF448 PF04296.8 CBK24738.2 - 0.27 10.8 3.0 19 4.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF448) FPL PF09758.4 CBK24739.2 - 3.2e-46 156.7 10.5 3.2e-46 156.7 7.3 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein RAI16-like PF10257.4 CBK24739.2 - 3.9e-05 22.7 5.7 0.0002 20.4 1.7 2.5 1 1 1 2 2 2 2 Retinoic acid induced 16-like protein RIX1 PF08167.7 CBK24739.2 - 0.0012 18.5 0.9 0.0029 17.2 0.6 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 CBK24740.2 - 2.9e-10 40.3 1.9 0.022 15.2 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 CBK24740.2 - 6.5e-09 35.1 3.9 0.39 10.9 0.0 5.8 6 0 0 6 6 6 4 HEAT repeat CLASP_N PF12348.3 CBK24740.2 - 2.1e-06 27.2 0.5 0.00034 20.0 0.0 3.0 2 2 1 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 CBK24740.2 - 4.4e-05 23.6 2.3 0.76 10.1 0.1 4.2 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 CBK24740.2 - 0.13 12.1 0.8 16 5.3 0.0 3.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DEAD PF00270.24 CBK24742.2 - 5.4e-34 117.1 0.0 1.4e-33 115.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK24742.2 - 1.2e-07 31.7 0.0 6.6e-07 29.3 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBK24742.2 - 0.02 13.6 0.0 0.066 12.0 0.0 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_19 PF13245.1 CBK24742.2 - 0.045 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 CBK24742.2 - 0.049 12.7 0.1 0.08 11.9 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Tim17 PF02466.14 CBK24746.2 - 2.2e-15 56.8 2.4 2.8e-15 56.4 1.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ank_4 PF13637.1 CBK24747.2 - 3.4e-27 94.3 12.8 1.3e-10 41.5 0.1 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBK24747.2 - 2.4e-26 91.8 5.4 1e-16 61.0 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBK24747.2 - 1.2e-23 82.6 4.8 3.3e-09 36.6 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBK24747.2 - 3.9e-22 76.8 8.6 3.4e-09 36.0 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CBK24747.2 - 2.1e-19 67.6 8.2 4.7e-08 32.5 0.1 4.7 4 1 0 4 4 4 4 Ankyrin repeat MORN PF02493.15 CBK24748.2 - 0.00055 19.4 1.0 0.00055 19.4 0.7 3.4 3 0 0 3 3 3 2 MORN repeat NTP_transf_2 PF01909.18 CBK24749.2 - 3e-06 27.4 0.0 3.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cpn60_TCP1 PF00118.19 CBK24750.2 - 6.1e-156 519.8 0.3 7e-156 519.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_mis_repair PF01119.14 CBK24751.2 - 7.5e-18 64.1 0.1 1.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBK24751.2 - 6.6e-10 38.7 0.2 1.4e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBK24751.2 - 6.5e-05 22.6 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med15 PF09606.5 CBK24751.2 - 0.22 9.6 6.3 0.29 9.2 4.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Metallophos PF00149.23 CBK24752.2 - 2.3e-43 147.9 0.4 2.8e-43 147.6 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Big_5 PF13205.1 CBK24753.2 - 5.1e-16 59.2 11.3 2.6e-05 24.7 0.0 5.7 6 0 0 6 6 6 3 Bacterial Ig-like domain fn3 PF00041.16 CBK24753.2 - 0.054 13.6 0.0 0.34 11.0 0.0 2.5 1 1 0 1 1 1 0 Fibronectin type III domain Yae1_N PF09811.4 CBK24755.2 - 0.0031 17.0 18.6 0.0084 15.6 1.5 3.8 2 1 2 4 4 4 3 Essential protein Yae1, N terminal MFS_1 PF07690.11 CBK24756.2 - 9.9e-39 133.0 18.4 1.2e-38 132.7 12.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK24756.2 - 2e-13 49.7 18.8 3.2e-13 49.0 13.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 CBK24756.2 - 4.1e-05 23.2 4.4 0.00011 21.8 0.4 3.4 3 1 1 4 4 4 1 MFS_1 like family MFS_2 PF13347.1 CBK24756.2 - 0.00061 18.3 7.6 0.00061 18.3 5.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 CBK24756.2 - 0.0058 14.8 7.7 0.0039 15.3 1.9 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector DnaJ PF00226.26 CBK24757.2 - 1.1e-18 66.6 0.1 2.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain ParA PF10609.4 CBK24759.2 - 7.6e-29 99.4 0.0 1.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBK24759.2 - 3.2e-17 62.6 0.0 4.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CBK24759.2 - 2.8e-08 33.1 0.0 5e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CBK24759.2 - 9.9e-08 31.3 1.0 2.8e-06 26.6 0.5 2.3 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 CBK24759.2 - 1.5e-06 28.2 0.0 9.8e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CBK24759.2 - 2.9e-05 22.9 0.2 4.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 CBK24759.2 - 0.00074 18.9 0.2 0.0011 18.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.1 CBK24759.2 - 0.0008 19.0 0.5 0.18 11.4 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBK24759.2 - 0.0036 16.8 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 CBK24759.2 - 0.012 14.7 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBK24759.2 - 0.023 13.5 0.1 0.035 12.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 CBK24759.2 - 0.025 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 CBK24759.2 - 0.026 13.9 0.1 0.075 12.4 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain YhjQ PF06564.7 CBK24759.2 - 0.031 13.6 0.2 0.056 12.7 0.1 1.6 1 1 0 1 1 1 0 YhjQ protein AAA_17 PF13207.1 CBK24759.2 - 0.033 14.9 0.1 0.049 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 CBK24759.2 - 0.035 13.2 0.1 0.062 12.4 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 CBK24759.2 - 0.042 13.3 0.5 0.33 10.5 0.3 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBK24759.2 - 0.068 13.1 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CBK24759.2 - 0.071 13.4 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain P12 PF12669.2 CBK24759.2 - 0.1 12.8 2.6 0.18 12.0 1.8 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family AAA_30 PF13604.1 CBK24759.2 - 0.15 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain DDE_Tnp_1_6 PF13751.1 CBK24759.2 - 0.39 10.7 2.1 0.77 9.7 1.5 1.4 1 1 0 1 1 1 0 Transposase DDE domain IMPDH PF00478.20 CBK24760.2 - 2e-135 451.2 2.6 2.4e-135 450.9 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CBK24760.2 - 3.6e-15 55.4 0.2 1.1e-06 28.3 0.1 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CBK24760.2 - 1.8e-12 47.0 4.4 1e-09 38.0 0.7 3.0 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 CBK24760.2 - 6e-09 35.1 2.7 2.1e-08 33.4 1.9 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CBK24760.2 - 7.4e-08 31.9 1.7 2.3e-07 30.3 0.7 2.1 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 CBK24760.2 - 2.5e-06 26.7 1.5 7.4e-06 25.2 0.6 2.1 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 CBK24760.2 - 0.0051 16.0 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 KDPG and KHG aldolase NanE PF04131.9 CBK24760.2 - 0.027 13.4 1.1 1.6 7.6 0.9 3.0 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.7 CBK24760.2 - 0.035 13.0 0.2 0.28 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.12 CBK24760.2 - 0.056 12.2 1.9 0.73 8.5 0.0 2.7 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) KTI12 PF08433.5 CBK24761.2 - 2e-11 43.5 0.5 3.8e-10 39.4 0.4 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CBK24761.2 - 2.4e-10 40.4 0.0 5.3e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBK24761.2 - 3.8e-07 30.9 0.0 4.9e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBK24761.2 - 7.7e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 CBK24761.2 - 1.1e-05 24.6 0.0 0.00016 20.7 0.0 2.0 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_14 PF13173.1 CBK24761.2 - 0.00048 20.0 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK24761.2 - 0.0059 16.7 0.1 0.036 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBK24761.2 - 0.012 15.6 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain GvpD PF07088.6 CBK24761.2 - 0.024 12.9 0.0 0.03 12.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.1 CBK24761.2 - 0.033 14.1 0.0 0.045 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CBK24761.2 - 0.04 14.0 0.0 0.71 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 CBK24761.2 - 0.068 12.2 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin CPT PF07931.7 CBK24761.2 - 0.069 12.7 0.0 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ribosomal_L15e PF00827.12 CBK24762.2 - 4.1e-80 267.8 10.5 5.7e-79 264.0 7.3 1.9 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L16 PF00252.13 CBK24763.2 - 8.2e-31 106.5 0.2 1e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.3 CBK24763.2 - 0.14 11.8 0.3 0.14 11.8 0.2 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ribosomal_S16 PF00886.14 CBK24764.2 - 3.3e-25 87.5 0.0 4.3e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L24e PF01246.15 CBK24765.2 - 9.6e-32 108.6 1.7 9.6e-32 108.6 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.4 CBK24765.2 - 0.088 12.8 0.8 0.088 12.8 0.5 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) CDK5_activator PF03261.10 CBK24765.2 - 0.54 9.5 8.2 0.61 9.3 5.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TAF8_C PF10406.4 CBK24765.2 - 4.7 7.3 5.4 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term COPIIcoated_ERV PF07970.7 CBK24766.2 - 5e-35 121.1 1.2 6.9e-35 120.6 0.8 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Chorein_N PF12624.2 CBK24768.2 - 3.1e-14 52.5 1.7 1.7e-13 50.1 0.3 2.2 1 1 1 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Adaptin_N PF01602.15 CBK24769.2 - 3.5e-70 236.8 9.6 5.3e-70 236.2 6.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CBK24769.2 - 4e-50 168.8 0.1 1.1e-49 167.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CBK24769.2 - 6.6e-47 158.7 0.9 1.4e-46 157.6 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CBK24769.2 - 1.8e-07 31.3 1.7 0.094 13.0 0.1 4.8 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.17 CBK24769.2 - 2.7e-05 23.8 0.1 1.2 9.3 0.0 4.6 3 1 1 4 4 4 2 HEAT repeat AP4E_app_platf PF14807.1 CBK24769.2 - 0.017 15.3 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.2 CBK24769.2 - 0.026 14.3 5.5 0.61 9.9 0.0 4.4 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 NAPRTase PF04095.11 CBK24770.2 - 1.1e-32 113.2 0.0 2.4e-30 105.6 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Helicase_C_2 PF13307.1 CBK24771.2 - 1e-57 194.7 0.0 1.3e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBK24772.2 - 3.1e-36 124.3 2.0 4.5e-36 123.8 1.4 1.2 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CBK24772.2 - 2.6e-07 30.3 0.2 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK24772.2 - 7.9e-07 29.0 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.11 CBK24772.2 - 0.00056 19.2 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 CBK24772.2 - 0.00094 18.8 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 CBK24772.2 - 0.0014 17.4 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain T2SE PF00437.15 CBK24772.2 - 0.021 13.7 0.0 0.046 12.6 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 CBK24772.2 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 CBK24772.2 - 0.064 12.2 0.0 0.52 9.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF2201 PF09967.4 CBK24772.2 - 0.14 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) DAGAT PF03982.8 CBK24773.2 - 2e-09 36.5 0.2 2.6e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DDHD PF02862.12 CBK24774.2 - 0.038 13.7 6.2 0.32 10.7 2.2 2.0 1 1 0 2 2 2 0 DDHD domain BSP_II PF05432.6 CBK24774.2 - 0.3 10.3 25.9 1.1 8.5 4.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF3899 PF13038.1 CBK24774.2 - 0.41 10.8 4.0 0.73 10.0 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Pox_Ag35 PF03286.9 CBK24774.2 - 0.5 9.8 21.4 0.035 13.6 3.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 CBK24774.2 - 0.91 9.0 22.8 2.5 7.5 5.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin Peptidase_S49_N PF08496.5 CBK24774.2 - 0.92 9.2 7.0 0.96 9.2 0.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PRP1_N PF06424.7 CBK24774.2 - 1.6 9.0 15.6 0.56 10.5 4.9 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Myc_N PF01056.13 CBK24774.2 - 4.1 6.4 18.7 1.4 7.9 2.4 2.4 2 0 0 2 2 2 0 Myc amino-terminal region DUF2457 PF10446.4 CBK24774.2 - 6.7 5.3 30.1 0.18 10.5 7.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF1840 PF08895.6 CBK24774.2 - 6.8 6.7 7.4 7.6 6.6 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Voldacs PF03517.8 CBK24774.2 - 7.1 6.4 12.3 1 9.1 1.3 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling BSD PF03909.12 CBK24776.2 - 1.2e-06 28.1 0.0 5e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 BSD domain Metallophos PF00149.23 CBK24778.2 - 3e-33 114.9 0.1 3.9e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBK24779.2 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S10_plectin PF03501.10 CBK24780.2 - 2.5e-30 104.1 0.1 3.1e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Response_reg PF00072.19 CBK24781.2 - 5.4e-20 71.4 0.0 9.3e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CBK24781.2 - 2.1e-15 56.4 0.2 4.2e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rft-1 PF04506.8 CBK24782.2 - 1.1e-84 284.8 28.6 3.4e-83 279.8 19.8 2.0 1 1 0 1 1 1 1 Rft protein Ribosomal_S17 PF00366.15 CBK24783.2 - 1.4e-28 98.7 1.0 2.1e-28 98.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Sybindin PF04099.7 CBK24784.2 - 3.3e-34 117.6 0.2 3.9e-34 117.4 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBK24784.2 - 0.0047 16.7 0.1 0.0079 16.0 0.0 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region tRNA-synt_1b PF00579.20 CBK24785.2 - 7.8e-66 222.1 0.0 1e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.15 CBK24785.2 - 7.6e-25 86.5 0.0 1.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain DUF2024 PF09630.5 CBK24785.2 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Epimerase PF01370.16 CBK24786.2 - 1.9e-25 89.6 0.0 2.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBK24786.2 - 1.7e-13 50.1 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBK24786.2 - 4.7e-12 45.1 0.0 6.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK24786.2 - 3.8e-09 35.8 0.1 5.1e-08 32.1 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CBK24786.2 - 2e-06 26.9 0.0 8.2e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CBK24786.2 - 0.003 17.4 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CBK24786.2 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding LRR_8 PF13855.1 CBK24787.2 - 0.031 14.0 1.8 0.4 10.4 0.8 2.5 2 0 0 2 2 2 0 Leucine rich repeat WD40 PF00400.27 CBK24788.2 - 3.1e-09 36.3 10.5 0.19 11.6 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BORG_CEP PF14957.1 CBK24789.2 - 0.54 11.1 3.7 1.2 10.0 2.6 1.8 1 1 0 1 1 1 0 Cdc42 effector Neur_chan_memb PF02932.11 CBK24789.2 - 6.6 6.5 6.5 7.2 6.4 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2_jaz PF12171.3 CBK24790.2 - 1.1e-07 31.7 2.4 2.2e-07 30.7 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBK24790.2 - 5.1e-06 26.5 0.2 6.8e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CBK24790.2 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger AKAP95 PF04988.7 CBK24790.2 - 0.057 13.2 0.3 0.098 12.4 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.7 CBK24790.2 - 0.088 12.4 1.1 0.15 11.7 0.7 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-met PF12874.2 CBK24790.2 - 0.096 12.9 1.1 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type PyrI_C PF02748.10 CBK24790.2 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-U1 PF06220.7 CBK24790.2 - 1.3 8.5 5.4 2.9 7.5 3.7 1.6 1 1 0 1 1 1 0 U1 zinc finger Pkr1 PF08636.5 CBK24791.2 - 0.00064 19.7 6.0 0.00085 19.3 4.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 AgrB PF04647.10 CBK24791.2 - 0.072 12.1 4.8 0.033 13.2 1.6 1.6 1 1 0 1 1 1 0 Accessory gene regulator B DUF3311 PF11755.3 CBK24791.2 - 2.2 7.8 6.1 15 5.1 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3311) TIMELESS PF04821.9 CBK24792.2 - 0.0069 15.6 0.1 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Timeless protein LSM PF01423.17 CBK24793.2 - 3.2e-13 49.0 0.5 4e-13 48.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain CwfJ_C_1 PF04677.10 CBK24794.2 - 5.7e-29 100.2 1.8 5.7e-29 100.2 1.2 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DUF4450 PF14614.1 CBK24794.2 - 0.0015 17.6 0.2 0.0079 15.3 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4450) CwfJ_C_2 PF04676.9 CBK24795.2 - 1.4e-12 47.9 0.0 1.5e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-ZPR1 PF03367.8 CBK24796.2 - 1.1e-101 336.7 10.1 3.1e-53 179.2 0.3 2.8 3 0 0 3 3 3 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 CBK24796.2 - 0.092 12.4 4.4 0.13 11.9 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF4131 PF13567.1 CBK24796.2 - 0.25 10.7 0.1 0.52 9.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ribosomal_L6e PF01159.14 CBK24796.2 - 1.1 9.5 9.4 0.24 11.6 4.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L6e zf-C2H2_4 PF13894.1 CBK24796.2 - 8.5 6.9 9.9 18 5.9 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1610 PF07754.6 CBK24796.2 - 9.3 6.4 10.3 2.4 8.3 0.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) LRR_9 PF14580.1 CBK24797.2 - 2.9e-36 124.6 0.9 3.2e-36 124.5 0.6 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBK24797.2 - 6.2e-05 22.5 13.5 0.00043 19.8 2.2 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK24797.2 - 0.023 14.4 4.1 0.04 13.6 0.8 2.5 1 1 0 2 2 2 0 Leucine rich repeat GNT-I PF03071.10 CBK24798.2 - 2.6e-89 299.7 0.1 3.2e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_transf_8 PF01501.15 CBK24798.2 - 0.0019 17.5 0.2 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.1 CBK24798.2 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBK24798.2 - 0.0078 15.9 0.5 0.46 10.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 ATP-synt_D PF01813.12 CBK24799.2 - 1.5e-58 197.5 3.9 1.9e-58 197.2 2.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HALZ PF02183.13 CBK24799.2 - 0.00032 20.3 0.9 0.00097 18.8 0.6 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper Prefoldin PF02996.12 CBK24799.2 - 0.089 12.4 3.8 1.4 8.5 0.8 2.8 2 1 0 2 2 2 0 Prefoldin subunit GAS PF13851.1 CBK24799.2 - 0.28 10.3 8.4 0.085 12.0 1.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Glycos_transf_2 PF00535.21 CBK24800.2 - 2.9e-05 23.8 0.0 4.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 CBK24800.2 - 0.0011 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 OMPdecase PF00215.19 CBK24802.2 - 3e-30 105.2 0.0 5.6e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 CBK24802.2 - 5.8e-17 61.5 0.5 1.4e-16 60.3 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GAF PF01590.21 CBK24802.2 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 GAF domain Nop14 PF04147.7 CBK24803.2 - 4e-103 345.9 56.7 2.3e-102 343.4 39.3 2.1 1 1 0 1 1 1 1 Nop14-like family Ribosomal_L30 PF00327.15 CBK24804.2 - 3.8e-21 74.4 1.3 3.8e-21 74.4 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TPR_11 PF13414.1 CBK24806.2 - 6.3e-18 64.1 0.7 2.2e-11 43.2 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBK24806.2 - 3e-15 55.0 1.9 3.5e-07 29.5 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK24806.2 - 3.6e-13 48.3 0.8 7.4e-05 22.3 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBK24806.2 - 6.5e-09 35.5 0.0 0.0011 18.8 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK24806.2 - 5.4e-08 32.5 1.2 0.00056 19.7 0.0 2.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CBK24806.2 - 8.9e-06 25.8 0.0 0.11 13.0 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK24806.2 - 1e-05 25.2 0.1 0.029 14.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBK24806.2 - 2.2e-05 24.9 0.0 0.00012 22.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBK24806.2 - 4.5e-05 22.9 0.4 0.67 9.8 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK24806.2 - 6.7e-05 23.1 0.0 0.067 13.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24806.2 - 0.00028 20.7 0.5 0.0016 18.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK24806.2 - 0.0004 20.4 1.6 0.0013 18.7 0.2 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBK24806.2 - 0.003 17.8 0.2 0.18 12.1 0.0 2.4 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBK24806.2 - 0.017 14.8 0.0 0.82 9.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 CBK24806.2 - 0.048 13.3 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide deacetylase TPR_20 PF14561.1 CBK24806.2 - 0.079 13.0 0.6 1.3 9.2 0.4 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBK24806.2 - 0.08 12.1 2.1 0.13 11.3 0.2 2.1 2 1 0 2 2 2 0 Coatomer epsilon subunit DUF3128 PF11326.3 CBK24806.2 - 0.11 12.6 0.6 0.57 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) LCM PF04072.9 CBK24807.2 - 5.4e-08 32.6 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TrbH PF07283.6 CBK24807.2 - 0.051 13.4 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Conjugal transfer protein TrbH AAA PF00004.24 CBK24808.2 - 3.9e-11 43.2 0.0 8.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBK24808.2 - 5.8e-06 25.2 1.3 0.0002 20.2 0.0 2.6 1 1 2 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CBK24808.2 - 0.00017 21.6 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBK24808.2 - 0.00053 20.7 0.0 0.0016 19.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBK24808.2 - 0.0006 19.7 0.1 0.0023 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBK24808.2 - 0.00088 19.4 0.1 0.011 15.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBK24808.2 - 0.0012 18.8 0.0 0.0044 17.0 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 CBK24808.2 - 0.0028 17.5 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBK24808.2 - 0.0033 16.5 0.0 0.0064 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBK24808.2 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 CBK24808.2 - 0.016 15.3 0.0 0.12 12.5 0.0 2.3 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CBK24808.2 - 0.019 14.6 0.2 0.05 13.3 0.0 1.8 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.22 CBK24808.2 - 0.03 14.6 0.0 0.37 11.0 0.0 2.8 2 1 1 3 3 3 0 ABC transporter DNA_pol3_delta PF06144.8 CBK24808.2 - 0.039 13.4 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Zeta_toxin PF06414.7 CBK24808.2 - 0.053 12.6 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin EPL1 PF10513.4 CBK24808.2 - 0.12 12.5 8.1 0.28 11.3 5.6 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like RNA_pol_Rpb2_6 PF00562.23 CBK24809.2 - 2e-109 365.9 0.0 2.9e-109 365.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBK24809.2 - 9.6e-39 132.4 0.3 1.3e-38 131.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CBK24809.2 - 1.9e-22 79.5 0.0 3.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 CBK24809.2 - 4e-19 68.1 0.9 9.5e-19 66.9 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBK24809.2 - 5.5e-18 64.4 0.0 1.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBK24809.2 - 5.8e-13 48.5 0.6 1.3e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_7 PF04560.15 CBK24809.2 - 2.9e-12 46.6 0.0 7.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Sec23_trunk PF04811.10 CBK24810.2 - 6.9e-59 199.1 0.0 9.5e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBK24810.2 - 4.1e-30 103.2 0.2 8.5e-30 102.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CBK24810.2 - 4e-26 91.3 0.2 1.2e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBK24810.2 - 3e-19 68.2 8.3 6.2e-19 67.2 5.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBK24810.2 - 1.9e-12 46.6 0.0 3.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-A20 PF01754.11 CBK24810.2 - 0.081 12.5 1.7 0.29 10.7 1.2 2.1 1 0 0 1 1 1 0 A20-like zinc finger tRNA-synt_1e PF01406.14 CBK24811.2 - 6.6e-116 386.6 0.3 6.6e-116 386.6 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBK24811.2 - 7e-14 51.2 3.3 4e-06 25.7 0.4 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 CBK24811.2 - 0.00051 18.8 0.1 0.00051 18.8 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.6 CBK24811.2 - 0.00062 19.9 0.0 0.0034 17.5 0.0 2.3 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.17 CBK24811.2 - 0.18 9.7 0.0 0.18 9.7 0.0 3.3 3 1 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) ALG3 PF05208.8 CBK24812.2 - 8.9e-113 377.2 24.0 1.1e-112 377.0 16.7 1.1 1 0 0 1 1 1 1 ALG3 protein GFO_IDH_MocA PF01408.17 CBK24813.2 - 6.1e-14 52.5 0.1 1.5e-13 51.3 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CBK24813.2 - 0.00021 21.0 0.0 0.00055 19.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Nucleotid_trans PF03407.11 CBK24814.2 - 2e-17 63.6 0.1 2.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PTCB-BRCT PF12738.2 CBK24816.2 - 2.2e-10 40.2 4.3 1.3e-05 24.9 0.1 4.4 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 CBK24816.2 - 8.3e-07 29.0 4.6 0.0037 17.3 0.5 4.9 4 2 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain UDPGP PF01704.13 CBK24818.2 - 1.8e-08 33.3 0.0 2.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Thioredoxin_8 PF13905.1 CBK24819.2 - 1.9e-71 236.2 0.0 3.9e-25 87.7 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK24819.2 - 1.3e-22 80.0 0.1 6.3e-08 32.7 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin PF00085.15 CBK24819.2 - 6.8e-20 70.6 0.2 1e-07 31.5 0.0 4.9 3 2 1 4 4 4 2 Thioredoxin AhpC-TSA PF00578.16 CBK24819.2 - 2.8e-12 46.4 0.0 4e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CBK24819.2 - 6.9e-11 41.8 0.0 0.00038 20.0 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_7 PF13899.1 CBK24819.2 - 8.3e-06 25.7 0.1 0.2 11.7 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CBK24819.2 - 7.6e-05 22.2 0.0 0.41 10.2 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin SCO1-SenC PF02630.9 CBK24819.2 - 0.0014 18.2 0.0 1.5 8.4 0.0 2.9 3 0 0 3 3 3 2 SCO1/SenC Glutaredoxin PF00462.19 CBK24819.2 - 0.0037 17.2 1.2 10 6.1 0.0 4.7 4 2 0 4 4 4 1 Glutaredoxin NADH_4Fe-4S PF10589.4 CBK24819.2 - 0.0053 15.8 0.0 2.3 7.4 0.0 2.7 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_6 PF13848.1 CBK24819.2 - 0.0073 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain RestrictionMunI PF11407.3 CBK24819.2 - 0.087 12.4 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Type II restriction enzyme MunI RVT_connect PF06815.8 CBK24819.2 - 0.11 12.4 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase connection domain tRNA_edit PF04073.10 CBK24820.2 - 2.3e-14 53.2 0.0 2.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain GST_C PF00043.20 CBK24822.2 - 6.7e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBK24822.2 - 0.0033 17.2 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-C2H2_jaz PF12171.3 CBK24823.2 - 3.2e-05 23.9 8.6 0.0045 17.0 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBK24823.2 - 4.8e-05 23.4 3.4 0.002 18.1 0.4 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBK24823.2 - 0.00021 21.4 6.5 0.13 12.6 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Amelogenin PF02948.10 CBK24823.2 - 0.0023 18.5 12.4 0.0046 17.6 8.6 1.5 1 0 0 1 1 1 1 Amelogenin Med3 PF11593.3 CBK24823.2 - 0.0039 16.4 19.0 0.0049 16.1 13.2 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C2H2_2 PF12756.2 CBK24823.2 - 0.01 15.9 4.4 0.069 13.2 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBK24823.2 - 0.013 15.7 5.3 0.93 9.9 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CCDC84 PF14968.1 CBK24823.2 - 0.046 13.2 0.8 0.085 12.3 0.5 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 PyrI_C PF02748.10 CBK24823.2 - 0.047 13.1 7.8 1.3 8.5 0.4 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 CBK24823.2 - 0.13 12.2 2.9 3.7 7.5 0.0 2.5 1 1 1 2 2 2 0 C2H2-type zinc finger DUF4573 PF15140.1 CBK24823.2 - 0.2 11.2 15.7 0.35 10.4 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) zf-CHCC PF10276.4 CBK24823.2 - 0.32 10.8 3.2 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-H2C2_2 PF13465.1 CBK24823.2 - 1.4 9.3 7.6 2.1 8.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-UBP PF02148.14 CBK24823.2 - 2 8.6 4.9 0.45 10.6 0.6 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Fork_head_N PF08430.7 CBK24823.2 - 2.3 8.5 45.4 12 6.2 31.5 2.0 1 1 0 1 1 1 0 Forkhead N-terminal region Ribosomal_S7 PF00177.16 CBK24824.2 - 3.5e-41 140.2 0.2 4.2e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.27 CBK24825.2 - 2.8e-06 26.9 0.7 0.044 13.6 0.0 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat HSP70 PF00012.15 CBK24826.2 - 7.7e-39 133.0 1.0 1.1e-35 122.6 0.0 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBK24826.2 - 2.7e-07 29.5 0.0 1.9e-06 26.7 0.0 2.3 2 1 1 3 3 3 1 MreB/Mbl protein Cauli_DNA-bind PF03310.8 CBK24826.2 - 0.064 13.1 0.8 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Ribosomal_S9 PF00380.14 CBK24827.2 - 1.5e-33 115.5 0.1 1.7e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AICARFT_IMPCHas PF01808.13 CBK24828.2 - 1.3e-93 313.5 0.1 2e-93 312.9 0.1 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CBK24828.2 - 2e-26 91.7 0.0 5e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain N6-adenineMlase PF10237.4 CBK24828.2 - 0.0049 16.5 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Glyco_hydro_47 PF01532.15 CBK24829.2 - 1.9e-50 171.8 0.0 2.4e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Dus PF01207.12 CBK24830.2 - 6.3e-26 90.9 0.0 7.8e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF410 PF04190.8 CBK24831.2 - 3e-15 56.4 0.1 3.4e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2450 PF10475.4 CBK24832.2 - 0.00079 18.4 0.1 0.00086 18.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Exo_endo_phos PF03372.18 CBK24833.2 - 1.5e-23 84.0 0.3 2e-23 83.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family T2SE PF00437.15 CBK24833.2 - 0.15 10.9 0.1 0.25 10.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Met_10 PF02475.11 CBK24834.2 - 1.8e-63 213.7 0.0 2.3e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CBK24834.2 - 9.8e-07 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK24834.2 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBK24834.2 - 0.0029 17.1 0.1 0.0054 16.2 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 CBK24834.2 - 0.0033 17.0 0.1 0.0078 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 CBK24834.2 - 0.004 16.1 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 CBK24834.2 - 0.0042 16.4 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CBK24834.2 - 0.021 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBK24834.2 - 0.042 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.11 CBK24834.2 - 0.084 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF885 PF05960.6 CBK24835.2 - 0.039 13.1 0.2 0.05 12.7 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF433 PF04255.9 CBK24835.2 - 0.04 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HpcH_HpaI PF03328.9 CBK24836.2 - 3e-45 153.7 0.0 9.3e-45 152.1 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CBK24836.2 - 3.8e-13 48.9 0.0 5.6e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 CBK24836.2 - 0.0014 17.3 0.1 0.0021 16.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PEP-utilizers_C PF02896.13 CBK24836.2 - 0.018 13.9 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Sulfate_transp PF00916.15 CBK24837.2 - 1.6e-58 197.9 10.5 2.2e-58 197.5 7.3 1.1 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBK24837.2 - 1e-13 50.7 5.1 1e-13 50.7 3.5 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif DUF1282 PF06930.7 CBK24837.2 - 0.00033 20.3 2.1 0.00033 20.3 1.5 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1282) UMP1 PF05348.6 CBK24838.2 - 4.1e-07 30.0 0.0 5e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DEAD PF00270.24 CBK24839.2 - 5.8e-42 143.0 0.0 2.1e-39 134.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK24839.2 - 9.8e-23 79.8 0.1 2.4e-22 78.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TatD_DNase PF01026.16 CBK24840.2 - 2e-49 168.1 0.0 2.8e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase PUB PF09409.5 CBK24841.2 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 PUB domain WD40 PF00400.27 CBK24842.2 - 1.1e-28 97.9 8.5 4.7e-10 38.9 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.7 CBK24842.2 - 0.027 14.1 1.3 0.11 12.1 0.2 2.5 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CBK24842.2 - 0.06 12.8 0.2 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Lar_restr_allev PF14354.1 CBK24842.2 - 0.29 11.4 1.7 1.6 9.0 0.2 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar RabGAP-TBC PF00566.13 CBK24843.2 - 0.028 13.8 2.7 0.049 13.0 1.9 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TLD PF07534.11 CBK24844.2 - 2.6e-13 50.1 0.0 4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 TLD DUF1533 PF07550.6 CBK24844.2 - 0.09 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) Cas_csx3 PF09620.5 CBK24844.2 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Alpha-amylase_C PF02806.13 CBK24845.2 - 0.0013 18.8 0.1 0.032 14.3 0.0 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CBK24845.2 - 0.031 13.6 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Whi5 PF08528.6 CBK24845.2 - 2.7 7.6 4.6 1.3 8.7 1.3 1.9 2 0 0 2 2 2 0 Whi5 like Peptidase_C1 PF00112.18 CBK24846.2 - 4.5e-63 213.0 5.6 6.6e-63 212.5 3.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBK24846.2 - 1.9e-10 40.8 0.5 3.1e-10 40.1 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) EMP24_GP25L PF01105.19 CBK24847.2 - 8e-19 68.0 0.4 3.1e-17 62.8 0.3 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Xpo1 PF08389.7 CBK24848.2 - 1.3e-11 44.6 1.6 2.2e-11 43.8 0.9 1.5 1 1 0 1 1 1 1 Exportin 1-like protein DNA_pol_phi PF04931.8 CBK24848.2 - 2.5e-05 22.2 0.2 3.1e-05 21.9 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi TPR_7 PF13176.1 CBK24848.2 - 0.058 13.2 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Cor1 PF04803.7 CBK24848.2 - 0.17 11.6 5.8 0.14 11.8 2.3 1.9 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region FKBP_C PF00254.23 CBK24849.2 - 2.7e-32 110.6 0.0 6.3e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3112 PF11309.3 CBK24849.2 - 0.57 9.9 3.3 0.26 11.0 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) NeA_P2 PF12312.3 CBK24850.2 - 1.8 7.6 5.8 0.37 9.9 1.4 1.6 1 1 1 2 2 2 0 Nepovirus subgroup A polyprotein ADK PF00406.17 CBK24851.2 - 5.1e-37 127.0 0.0 6.1e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBK24851.2 - 8e-12 44.6 3.5 9e-11 41.2 2.4 2.1 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 CBK24851.2 - 4.1e-05 23.8 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBK24851.2 - 0.00017 22.4 0.0 0.00024 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain A2L_zn_ribbon PF08792.5 CBK24851.2 - 0.016 14.6 0.3 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2HC_2 PF13913.1 CBK24851.2 - 0.019 14.6 0.2 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_29 PF13555.1 CBK24851.2 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DZR PF12773.2 CBK24851.2 - 0.025 14.3 0.4 0.052 13.3 0.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.7 CBK24851.2 - 0.062 13.1 0.6 0.38 10.5 0.1 2.2 2 0 0 2 2 2 0 NinF protein Mg_chelatase PF01078.16 CBK24851.2 - 0.064 12.4 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TerY-C PF15616.1 CBK24851.2 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain AAA_33 PF13671.1 CBK24851.2 - 0.13 12.1 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhnA_Zn_Ribbon PF08274.7 CBK24851.2 - 4.1 7.2 5.7 31 4.4 3.9 2.1 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-CCHC PF00098.18 CBK24852.2 - 1.7e-11 43.4 47.4 5.3e-06 26.1 1.0 7.1 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.1 CBK24852.2 - 0.0054 16.2 1.2 0.0054 16.2 0.8 5.8 6 1 1 7 7 7 2 Zinc knuckle eIF3g PF12353.3 CBK24852.2 - 0.037 13.9 0.5 0.037 13.9 0.4 5.3 3 2 3 6 6 6 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 CBK24852.2 - 0.038 13.6 1.4 0.038 13.6 1.0 6.9 7 0 0 7 7 7 0 Zinc knuckle ProRS-C_1 PF09180.6 CBK24852.2 - 7.1 6.6 17.2 30 4.6 0.1 5.2 3 2 2 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Ribosomal_S7 PF00177.16 CBK24853.2 - 3.5e-41 140.2 0.2 4.2e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C2H2_jaz PF12171.3 CBK24854.2 - 3.7e-05 23.7 8.6 0.0048 17.0 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CBK24854.2 - 5.3e-05 23.2 3.4 0.0022 18.0 0.4 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBK24854.2 - 0.00024 21.2 6.5 0.14 12.5 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Amelogenin PF02948.10 CBK24854.2 - 0.00029 21.4 18.2 0.00053 20.6 12.6 1.5 1 0 0 1 1 1 1 Amelogenin Med3 PF11593.3 CBK24854.2 - 0.0017 17.6 23.3 0.0024 17.2 16.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C2H2_2 PF12756.2 CBK24854.2 - 0.011 15.7 4.4 0.074 13.1 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBK24854.2 - 0.015 15.5 5.3 0.99 9.8 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CCDC84 PF14968.1 CBK24854.2 - 0.042 13.3 0.5 0.075 12.5 0.3 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 PyrI_C PF02748.10 CBK24854.2 - 0.055 12.9 7.9 1.4 8.4 0.5 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 CBK24854.2 - 0.15 12.0 2.9 3.9 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.4 CBK24854.2 - 0.36 10.7 3.2 14 5.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain Fork_head_N PF08430.7 CBK24854.2 - 0.69 10.3 54.8 8.7 6.7 38.0 2.3 1 1 0 1 1 1 0 Forkhead N-terminal region zf-H2C2_2 PF13465.1 CBK24854.2 - 1.3 9.4 7.2 2.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-UBP PF02148.14 CBK24854.2 - 2.2 8.4 4.9 0.48 10.5 0.6 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GST_C PF00043.20 CBK24855.2 - 6.7e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBK24855.2 - 0.0033 17.2 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA_edit PF04073.10 CBK24857.2 - 2.3e-14 53.2 0.0 2.6e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Thioredoxin_8 PF13905.1 CBK24858.2 - 2.6e-28 97.9 0.0 3.4e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBK24858.2 - 3.6e-10 40.0 0.0 4.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 CBK24858.2 - 1.7e-08 34.0 0.0 1.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 CBK24858.2 - 4.9e-08 32.6 0.0 5.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK24858.2 - 8.2e-08 31.9 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CBK24858.2 - 0.001 19.0 0.1 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like DUF3008 PF11450.3 CBK24858.2 - 0.0072 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) SCO1-SenC PF02630.9 CBK24858.2 - 0.0074 15.9 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC RVT_connect PF06815.8 CBK24858.2 - 0.054 13.3 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase connection domain Kinesin PF00225.18 CBK24859.2 - 7.1e-96 320.8 2.1 8.3e-96 320.5 1.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF1423 PF07227.6 CBK24859.2 - 0.039 12.6 0.3 0.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) Fe-ADH PF00465.14 CBK24860.2 - 0.0053 15.4 0.0 0.0073 14.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CBK24860.2 - 0.024 13.5 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase Fe-ADH PF00465.14 CBK24861.2 - 4.4e-39 134.1 0.1 5.4e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK24861.2 - 2.5e-28 99.0 0.1 3e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CBK24861.2 - 6.6e-07 28.5 0.0 9.4e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.15 CBK24861.2 - 0.028 13.7 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 AIR carboxylase HHH_5 PF14520.1 CBK24862.2 - 1.8e-06 27.9 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 CBK24862.2 - 6.2e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 CBK24862.2 - 0.054 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HSBP1 PF06825.7 CBK24862.2 - 0.1 12.2 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Aldose_epim PF01263.15 CBK24863.2 - 3e-78 262.9 0.0 3.5e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AMP-binding PF00501.23 CBK24864.2 - 3.5e-82 276.0 0.0 4.1e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EF-hand_4 PF12763.2 CBK24865.2 - 8.7e-95 311.3 0.0 7e-17 61.0 0.0 5.2 5 0 0 5 5 5 5 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CBK24865.2 - 3.5e-32 110.3 12.0 6.5e-05 22.9 0.1 5.3 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.1 CBK24865.2 - 4.5e-24 83.8 6.4 0.0049 16.4 0.0 5.4 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.27 CBK24865.2 - 1e-17 62.0 16.2 0.11 11.8 0.1 9.3 10 0 0 10 10 10 5 EF hand End3 PF12761.2 CBK24865.2 - 4.4e-14 52.5 8.0 0.083 12.5 0.0 6.2 6 0 0 6 6 6 5 Actin cytoskeleton-regulatory complex protein END3 EF-hand_6 PF13405.1 CBK24865.2 - 1.4e-11 43.1 18.7 4.9 7.3 0.0 9.9 10 0 0 10 10 10 5 EF-hand domain DUF2421 PF10334.4 CBK24865.2 - 3.8e-11 43.0 1.7 0.59 9.7 0.0 5.2 3 2 2 5 5 5 4 Protein of unknown function (DUF2421) MgsA_C PF12002.3 CBK24865.2 - 7.5e-07 28.9 10.0 7.5 6.2 0.0 5.4 5 0 0 5 5 5 5 MgsA AAA+ ATPase C terminal VCBS PF13517.1 CBK24865.2 - 6e-05 23.3 2.8 83 3.6 0.0 5.3 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.1 CBK24865.2 - 0.00057 19.1 36.8 1.3 8.4 0.1 7.9 10 0 0 10 10 10 5 EF hand Secretin_N PF03958.12 CBK24865.2 - 0.0034 17.5 3.9 1.4e+02 2.7 0.0 5.3 5 0 0 5 5 5 0 Bacterial type II/III secretion system short domain Ribosomal_S2 PF00318.15 CBK24865.2 - 0.13 11.4 1.1 0.22 10.7 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 FG-GAP PF01839.18 CBK24865.2 - 0.69 9.6 11.8 1.1e+02 2.6 0.1 5.3 5 0 0 5 5 5 0 FG-GAP repeat Nucleoplasmin PF03066.10 CBK24865.2 - 0.7 9.3 30.4 0.26 10.7 2.0 5.1 5 0 0 5 5 5 0 Nucleoplasmin PRKCSH PF07915.8 CBK24866.2 - 0.016 15.9 0.5 0.031 15.0 0.4 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Ribosomal_L21e PF01157.13 CBK24867.2 - 2e-38 130.1 2.9 3.3e-38 129.4 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Put_Phosphatase PF06888.7 CBK24867.2 - 0.067 12.3 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase PP2C PF00481.16 CBK24868.2 - 4.8e-24 85.1 0.0 5.4e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBK24868.2 - 0.00087 19.0 0.0 0.00099 18.8 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.20 CBK24869.2 - 0.00031 19.9 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CBK24870.2 - 9.6e-17 60.9 0.0 4e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24870.2 - 3.7e-08 32.7 0.0 6.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBK24870.2 - 0.009 14.9 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like HSP70 PF00012.15 CBK24871.2 - 6.5e-14 50.7 0.2 6.5e-14 50.7 0.1 1.5 2 0 0 2 2 2 1 Hsp70 protein Ribosomal_L13 PF00572.13 CBK24871.2 - 0.049 13.6 0.3 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L13 Auts2 PF15336.1 CBK24871.2 - 1.3 8.9 14.5 0.044 13.8 1.6 2.4 1 1 1 2 2 2 0 Autism susceptibility gene 2 protein RRM_2 PF04059.7 CBK24872.2 - 5.4e-25 87.2 0.3 9.1e-25 86.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 CBK24872.2 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pga1 PF10333.4 CBK24872.2 - 0.073 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator DUF4111 PF13427.1 CBK24872.2 - 0.19 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Epimerase PF01370.16 CBK24873.2 - 4.5e-52 176.8 0.0 6.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBK24873.2 - 1.1e-06 27.8 0.0 1.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBK24873.2 - 5e-06 25.6 1.3 2.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CBK24873.2 - 3e-05 22.8 0.5 9.2e-05 21.2 0.3 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBK24873.2 - 0.00011 21.2 0.3 0.00071 18.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Pox_MCEL PF03291.11 CBK24875.2 - 9.8e-43 146.2 0.1 1.2e-42 145.9 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 CBK24875.2 - 1.4e-12 47.4 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK24875.2 - 3e-10 40.4 0.0 5.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK24875.2 - 7.9e-10 39.0 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBK24875.2 - 9.5e-09 35.1 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBK24875.2 - 3.1e-08 34.0 0.0 5.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK24875.2 - 1.1e-06 29.2 0.0 1.5e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK24875.2 - 0.00043 20.2 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CBK24875.2 - 0.0014 18.0 1.0 0.0028 17.0 0.0 1.9 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 CBK24875.2 - 0.0039 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 CBK24875.2 - 0.0092 15.3 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.6 CBK24875.2 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MORN PF02493.15 CBK24876.2 - 3.1e-33 111.5 50.6 9.7e-05 21.8 0.3 13.5 13 0 0 13 13 13 8 MORN repeat Ribosomal_L30 PF00327.15 CBK24876.2 - 1.5e-20 72.5 1.3 2.7e-20 71.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MIP-T3 PF10243.4 CBK24876.2 - 0.019 13.4 31.6 0.024 13.1 21.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 CBK24876.2 - 0.024 12.6 8.5 0.028 12.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CBK24876.2 - 0.088 10.5 13.6 0.11 10.2 9.4 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 CBK24876.2 - 0.28 10.6 20.8 0.43 9.9 14.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO NPR3 PF03666.8 CBK24876.2 - 0.66 8.4 13.5 0.93 7.9 9.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.10 CBK24876.2 - 1.3 7.5 9.2 1.8 7.1 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.3 CBK24876.2 - 1.4 7.4 14.6 2.2 6.7 10.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Menin PF05053.8 CBK24876.2 - 4.8 5.2 7.1 6.7 4.7 4.9 1.1 1 0 0 1 1 1 0 Menin Fcf1 PF04900.7 CBK24877.2 - 2.3e-17 62.9 1.0 5e-17 61.8 0.7 1.6 1 0 0 1 1 1 1 Fcf1 PerC PF06069.6 CBK24877.2 - 0.17 11.9 1.9 0.52 10.3 0.5 2.2 2 0 0 2 2 2 0 PerC transcriptional activator Aa_trans PF01490.13 CBK24878.2 - 1.9e-43 148.4 30.6 2.3e-43 148.2 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBK24878.2 - 1.8e-07 30.3 22.0 3.3e-07 29.4 15.2 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family SSrecog PF03531.9 CBK24879.2 - 1.8e-47 161.5 0.1 2.3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Collagen PF01391.13 CBK24880.2 - 3e-06 26.6 10.6 3e-06 26.6 7.3 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TIM21 PF08294.6 CBK24881.2 - 4.4e-17 62.0 0.0 5.8e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 CBK24881.2 - 7.3e-05 22.2 0.0 0.00057 19.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MMR_HSR1_C PF08438.5 CBK24882.2 - 2.4e-23 82.4 2.0 1.2e-22 80.2 1.4 2.0 1 1 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CBK24882.2 - 1e-17 64.1 0.0 3.1e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK24882.2 - 2.3e-09 36.7 0.2 2.7e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CBK24882.2 - 0.13 11.0 0.7 0.47 9.1 0.0 2.0 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 CBK24882.2 - 0.13 11.7 0.7 8.8 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FH2 PF02181.18 CBK24883.2 - 3.8e-70 236.6 1.3 3.8e-70 236.6 0.9 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Fe_bilin_red PF05996.7 CBK24883.2 - 0.00093 18.7 1.5 0.0016 17.9 1.0 1.4 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Borrelia_lipo_2 PF06238.6 CBK24883.2 - 0.026 14.5 1.4 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein AAA_23 PF13476.1 CBK24883.2 - 2.3 8.4 8.1 21 5.3 5.6 2.3 1 1 0 1 1 1 0 AAA domain EamA PF00892.15 CBK24884.2 - 1.3e-06 28.4 0.9 1.3e-06 28.4 0.7 3.3 3 1 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 CBK24884.2 - 4.4e-06 25.9 10.0 2.5e-05 23.5 7.0 2.1 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 CBK24884.2 - 0.0032 17.1 20.0 0.0066 16.1 7.5 2.9 2 2 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBK24884.2 - 0.0098 16.0 2.5 0.0098 16.0 1.8 3.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Phage_cap_P2 PF05125.7 CBK24884.2 - 0.029 13.2 0.0 0.083 11.7 0.0 1.7 2 0 0 2 2 2 0 Phage major capsid protein, P2 family YWFCY PF14293.1 CBK24884.2 - 0.24 11.2 4.7 1.6 8.6 0.3 2.9 2 0 0 2 2 2 0 YWFCY protein DUF2976 PF11190.3 CBK24884.2 - 3.4 7.2 20.0 0.12 11.9 1.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) UDPGP PF01704.13 CBK24886.2 - 2.4e-13 49.3 0.0 3.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3737 PF12541.3 CBK24886.2 - 0.085 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) G8 PF10162.4 CBK24886.2 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 G8 domain Nop PF01798.13 CBK24887.2 - 1.1e-59 199.9 0.1 2.8e-59 198.7 0.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBK24887.2 - 1.4e-26 92.0 0.1 3.7e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBK24887.2 - 3.9e-23 81.3 1.2 3.9e-23 81.3 0.9 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 CBK24887.2 - 0.12 12.2 17.7 0.18 11.7 12.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 CBK24887.2 - 0.22 11.1 47.0 0.35 10.5 32.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 CBK24887.2 - 0.83 9.4 13.8 2.5 7.8 9.5 1.9 2 0 0 2 2 2 0 DDHD domain AAA_11 PF13086.1 CBK24887.2 - 1.6 8.2 12.0 3.3 7.2 8.3 1.5 1 0 0 1 1 1 0 AAA domain YqfQ PF14181.1 CBK24887.2 - 1.7 8.7 32.1 3.2 7.7 22.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 CBK24887.2 - 2.7 7.7 28.8 5.3 6.8 20.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SQS_PSY PF00494.14 CBK24888.2 - 1e-28 100.4 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase UPF0004 PF00919.15 CBK24888.2 - 0.086 12.6 0.1 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 SDA1 PF05285.7 CBK24889.2 - 8.3e-33 114.0 78.1 5.1e-30 104.8 51.6 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CBK24889.2 - 5.7e-16 58.5 0.2 1.2e-14 54.3 0.0 2.6 2 0 0 2 2 2 1 NUC130/3NT domain BUD22 PF09073.5 CBK24889.2 - 0.2 10.7 77.1 0.0049 16.0 46.3 2.2 2 0 0 2 2 2 0 BUD22 Thioredoxin PF00085.15 CBK24890.2 - 1.3e-25 89.0 0.0 3.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.7 CBK24890.2 - 7.5e-08 32.8 1.2 7.5e-08 32.8 0.9 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CBK24890.2 - 0.00011 22.3 4.0 0.00084 19.5 0.0 3.4 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK24890.2 - 0.00071 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CBK24890.2 - 0.0017 18.4 0.2 0.05 13.7 0.0 2.9 2 2 2 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBK24890.2 - 0.012 15.4 0.1 0.099 12.4 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin domain DDE_Tnp_1_2 PF13586.1 CBK24890.2 - 0.024 14.8 0.9 0.038 14.1 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain NUC153 PF08159.7 CBK24890.2 - 0.087 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 NUC153 domain Rtt102p PF09510.5 CBK24890.2 - 0.12 12.3 4.5 0.52 10.2 1.1 2.4 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein FtsJ PF01728.14 CBK24892.2 - 1.1e-51 175.3 0.1 1.6e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.1 CBK24892.2 - 0.034 11.9 0.1 0.057 11.2 0.0 1.4 2 0 0 2 2 2 0 Virus-capping methyltransferase Methyltransf_23 PF13489.1 CBK24892.2 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ebp2 PF05890.7 CBK24893.2 - 1.8e-24 86.4 11.5 2.2e-24 86.2 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 MutS_I PF01624.15 CBK24893.2 - 0.0017 18.3 0.1 0.0023 17.9 0.1 1.2 1 0 0 1 1 1 1 MutS domain I Spectrin PF00435.16 CBK24893.2 - 0.016 15.4 3.0 0.066 13.4 2.1 1.9 1 1 0 1 1 1 0 Spectrin repeat Noc2 PF03715.8 CBK24894.2 - 1e-86 290.5 4.3 1.2e-86 290.2 3.0 1.0 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.7 CBK24894.2 - 0.00016 19.8 0.0 0.00024 19.2 0.0 1.2 1 0 0 1 1 1 1 Nop14-like family Spore_III_AF PF09581.5 CBK24894.2 - 0.11 12.3 0.1 0.21 11.4 0.0 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) RRM_1 PF00076.17 CBK24895.2 - 1.2e-33 114.5 0.0 3.5e-15 55.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24895.2 - 8.7e-30 102.5 0.1 4.4e-11 42.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24895.2 - 2.7e-24 84.7 0.9 1.3e-07 31.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CBK24895.2 - 6.4e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Limkain-b1 PF11608.3 CBK24895.2 - 0.00016 21.3 0.2 0.0017 18.0 0.0 2.6 2 0 0 2 2 2 1 Limkain b1 DUF1777 PF08648.7 CBK24895.2 - 0.0023 17.6 37.4 0.0051 16.5 25.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CBK24895.2 - 0.27 9.6 14.5 0.35 9.2 10.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rhodanese PF00581.15 CBK24896.2 - 1.2e-14 54.5 0.0 1.8e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain ArsA_ATPase PF02374.10 CBK24897.2 - 2e-100 335.8 0.1 2.8e-100 335.2 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CBK24897.2 - 9.9e-21 74.0 0.0 7.7e-20 71.1 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 CBK24897.2 - 2.8e-08 33.4 0.1 1.2e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_31 PF13614.1 CBK24897.2 - 3e-08 33.7 0.2 4.4e-07 29.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CBK24897.2 - 1.8e-07 30.6 0.0 9.2e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 CBK24897.2 - 1.7e-06 27.3 0.1 0.0021 17.1 0.0 3.0 2 1 0 3 3 3 1 ATPase MipZ AAA_25 PF13481.1 CBK24897.2 - 0.0001 21.7 0.1 0.00077 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 CBK24897.2 - 0.0013 18.1 0.0 0.0045 16.3 0.0 1.8 2 0 0 2 2 2 1 YhjQ protein AAA_10 PF12846.2 CBK24897.2 - 0.0036 16.7 0.1 0.0078 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain IstB_IS21 PF01695.12 CBK24897.2 - 0.0041 16.5 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 CBK24897.2 - 0.0068 15.4 0.1 0.016 14.1 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 CBK24897.2 - 0.0084 14.9 0.0 0.024 13.4 0.0 1.7 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 CBK24897.2 - 0.0087 15.7 0.8 0.062 13.0 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBK24897.2 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ParA PF10609.4 CBK24897.2 - 0.012 15.5 0.4 0.059 13.2 0.2 2.2 2 0 0 2 2 2 0 ParA/MinD ATPase like ATP_bind_1 PF03029.12 CBK24897.2 - 0.012 15.1 0.2 0.043 13.3 0.1 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1611 PF07755.6 CBK24897.2 - 0.028 13.0 0.0 0.15 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) VirC1 PF07015.6 CBK24897.2 - 0.03 13.3 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein AAA_18 PF13238.1 CBK24897.2 - 0.032 14.5 0.1 0.12 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 CBK24897.2 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 CBK24897.2 - 0.055 14.2 0.0 0.16 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 CBK24897.2 - 0.061 12.4 0.0 0.17 11.0 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 CBK24897.2 - 0.067 13.3 0.3 1.1 9.4 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK24897.2 - 0.078 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CBK24897.2 - 0.083 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.13 CBK24897.2 - 0.091 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ResIII PF04851.10 CBK24897.2 - 0.1 12.4 0.4 0.23 11.2 0.3 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 CBK24897.2 - 0.1 11.6 0.0 0.41 9.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin CTP_synth_N PF06418.9 CBK24897.2 - 0.11 11.5 0.2 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 CTP synthase N-terminus TelA PF05816.6 CBK24897.2 - 0.13 10.9 0.1 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF2847 PF11009.3 CBK24898.2 - 0.075 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) XRN_N PF03159.13 CBK24900.2 - 0.0095 15.3 3.8 0.012 14.9 2.6 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Pet191_N PF10203.4 CBK24900.2 - 0.036 14.0 1.6 0.066 13.2 1.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF4175 PF13779.1 CBK24900.2 - 0.062 10.9 10.0 0.077 10.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CHCH PF06747.8 CBK24900.2 - 0.27 11.2 3.4 1.8 8.5 2.3 2.4 1 1 0 1 1 1 0 CHCH domain SDA1 PF05285.7 CBK24900.2 - 4.1 6.5 27.5 5.4 6.2 19.0 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 CBK24900.2 - 5.3 5.4 28.9 6.5 5.1 20.1 1.1 1 0 0 1 1 1 0 Daxx Family Prefoldin PF02996.12 CBK24901.2 - 4.6e-17 61.7 0.1 7e-17 61.1 0.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBK24901.2 - 0.037 13.7 0.6 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 Prefoldin subunit DUF2855 PF11017.3 CBK24901.2 - 0.087 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) GP41 PF00517.12 CBK24901.2 - 0.11 12.0 0.4 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Mnd1 PF03962.10 CBK24902.2 - 0.00057 19.6 10.3 0.00073 19.2 7.1 1.1 1 0 0 1 1 1 1 Mnd1 family HAP1_N PF04849.8 CBK24902.2 - 0.013 14.4 9.6 0.019 13.9 6.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SlyX PF04102.7 CBK24902.2 - 0.026 14.8 6.8 2.3 8.6 2.3 2.4 1 1 1 2 2 2 0 SlyX DUF1635 PF07795.6 CBK24902.2 - 0.044 13.1 5.2 0.051 12.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) NUFIP2 PF15293.1 CBK24902.2 - 0.063 11.9 2.6 0.076 11.7 1.8 1.0 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 DUF4559 PF15112.1 CBK24902.2 - 0.11 11.6 6.1 0.13 11.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CALCOCO1 PF07888.6 CBK24902.2 - 0.12 10.6 10.8 0.13 10.5 7.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TP53IP5 PF15331.1 CBK24902.2 - 0.13 12.1 6.8 0.17 11.7 4.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LUC7 PF03194.10 CBK24902.2 - 0.14 11.6 6.9 0.15 11.5 4.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Herpes_UL6 PF01763.11 CBK24902.2 - 0.16 10.1 4.1 0.2 9.8 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Allexi_40kDa PF05549.6 CBK24902.2 - 0.19 11.0 3.6 0.22 10.7 2.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Lipoprotein_6 PF01441.14 CBK24902.2 - 0.22 11.3 9.4 0.27 11.0 6.5 1.1 1 0 0 1 1 1 0 Lipoprotein Prp18 PF02840.10 CBK24902.2 - 0.28 10.9 5.0 0.37 10.5 3.4 1.1 1 0 0 1 1 1 0 Prp18 domain AAA_13 PF13166.1 CBK24902.2 - 0.3 9.4 10.9 0.32 9.3 7.5 1.0 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 CBK24902.2 - 0.33 10.8 12.5 0.43 10.4 8.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CBK24902.2 - 0.41 10.2 13.5 0.53 9.8 9.4 1.4 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CBK24902.2 - 0.52 8.1 6.8 0.61 7.8 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 CBK24902.2 - 0.6 8.4 8.4 0.59 8.4 5.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3373 PF11853.3 CBK24902.2 - 0.69 8.3 4.8 0.65 8.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CENP-H PF05837.7 CBK24902.2 - 0.72 10.0 14.7 1.1 9.4 10.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.10 CBK24902.2 - 0.91 9.0 11.4 3.7 7.0 3.6 2.3 1 1 1 2 2 2 0 Septum formation initiator CENP-Q PF13094.1 CBK24902.2 - 0.93 9.5 17.6 4.4 7.3 12.2 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2400 PF09674.5 CBK24902.2 - 0.94 9.1 3.4 1.1 8.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) bZIP_1 PF00170.16 CBK24902.2 - 1.2 9.1 14.0 1.1 9.2 2.8 2.4 1 1 1 2 2 2 0 bZIP transcription factor DUF2951 PF11166.3 CBK24902.2 - 1.2 8.9 10.3 2 8.2 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF342 PF03961.8 CBK24902.2 - 1.3 7.3 7.8 1.5 7.1 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 CBK24902.2 - 1.3 7.8 10.2 1.7 7.5 7.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Muted PF14942.1 CBK24902.2 - 2.5 7.9 11.3 3.4 7.5 7.8 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein RPN7 PF10602.4 CBK24902.2 - 3.4 7.0 8.1 5.9 6.2 5.5 1.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TROVE PF05731.6 CBK24902.2 - 4.1 6.0 9.6 4.3 5.9 6.6 1.1 1 0 0 1 1 1 0 TROVE domain CR6_interact PF10147.4 CBK24902.2 - 5 6.3 15.7 5 6.3 10.3 1.4 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Cas_CT1975 PF09344.5 CBK24902.2 - 6.2 6.0 9.2 7.8 5.7 6.4 1.1 1 0 0 1 1 1 0 CT1975-like protein Tropomyosin_1 PF12718.2 CBK24902.2 - 6.3 6.6 22.5 8.8 6.1 15.6 1.5 1 1 0 1 1 1 0 Tropomyosin like Orbi_VP5 PF00901.12 CBK24902.2 - 7 4.7 11.0 8.1 4.5 7.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ArfGap PF01412.13 CBK24903.2 - 1.1e-23 83.2 0.3 2.1e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_S21e PF01249.13 CBK24904.2 - 3.1e-26 91.1 0.1 3.6e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Clp_N PF02861.15 CBK24905.2 - 0.37 10.7 5.0 0.41 10.5 0.3 3.2 3 0 0 3 3 3 0 Clp amino terminal domain DSX_dimer PF08828.5 CBK24905.2 - 0.41 10.2 2.2 1.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Doublesex dimerisation domain vATP-synt_AC39 PF01992.11 CBK24906.2 - 1.4e-45 155.9 0.0 9.2e-45 153.2 0.0 2.2 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Svf1 PF08622.5 CBK24906.2 - 0.025 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Svf1-like Pkinase PF00069.20 CBK24907.2 - 2.1e-67 227.0 0.0 3e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24907.2 - 6e-47 159.8 0.0 8.6e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK24907.2 - 5.3e-09 35.4 0.0 8.9e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBK24907.2 - 0.031 13.9 0.0 0.79 9.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_19 PF14559.1 CBK24908.2 - 0.0058 16.9 4.1 0.017 15.4 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK24908.2 - 0.0084 16.0 1.4 0.07 13.0 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK24908.2 - 0.0092 15.8 0.2 0.0092 15.8 0.2 3.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CBK24908.2 - 0.096 12.6 7.1 0.9 9.6 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBK24908.2 - 0.12 13.1 1.2 0.45 11.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK24908.2 - 0.27 10.9 8.2 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 CBK24909.2 - 4.7e-15 54.9 0.0 2e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.26 CBK24909.2 - 1.2e-11 44.4 0.3 2.3e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_6 PF14259.1 CBK24909.2 - 3.4e-11 42.9 0.0 7.5e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24909.2 - 5.8e-06 26.0 0.1 1.8e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 CBK24909.2 - 9.8e-06 25.5 1.7 9.8e-06 25.5 1.2 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Ten_N PF06484.7 CBK24909.2 - 0.0021 17.2 3.0 0.014 14.5 2.5 1.9 2 0 0 2 2 2 1 Teneurin Intracellular Region Pyr_redox_2 PF07992.9 CBK24910.2 - 1.4e-33 116.4 0.0 1.8e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBK24910.2 - 3.2e-25 88.3 0.0 5.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBK24910.2 - 4.8e-16 58.9 0.6 2.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBK24910.2 - 5.3e-11 42.9 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBK24910.2 - 9.6e-06 24.6 0.7 2.8e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CBK24910.2 - 0.00018 20.4 0.3 0.00029 19.8 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBK24910.2 - 0.00021 20.4 3.8 0.001 18.2 1.8 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase DAO PF01266.19 CBK24910.2 - 0.00034 19.6 0.9 0.077 11.8 0.6 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBK24910.2 - 0.00067 18.2 0.3 0.0041 15.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 CBK24910.2 - 0.0019 17.3 0.1 0.0042 16.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CBK24910.2 - 0.017 15.1 2.9 0.2 11.7 0.3 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain eRF1_1 PF03463.10 CBK24911.2 - 2.4e-33 114.4 0.3 3.6e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CBK24911.2 - 2e-22 79.9 0.0 3.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBK24911.2 - 7.6e-22 77.7 0.0 2.5e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 peroxidase PF00141.18 CBK24911.2 - 0.0051 16.3 0.0 1.1 8.7 0.0 2.4 2 1 0 2 2 2 2 Peroxidase Pribosyltran_N PF13793.1 CBK24912.2 - 4.7e-43 145.6 0.2 5.7e-40 135.6 0.0 2.6 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBK24912.2 - 4.7e-29 101.4 0.1 9.7e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBK24912.2 - 1.7e-07 30.9 0.0 7.4e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBK24912.2 - 0.011 14.9 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_L6 PF00347.18 CBK24913.2 - 4.2e-30 104.0 5.9 1.1e-15 57.8 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 E1-E2_ATPase PF00122.15 CBK24914.2 - 2.1e-14 53.1 4.4 3.5e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBK24914.2 - 1.5e-13 51.3 0.0 6e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBK24914.2 - 8.3e-10 39.4 1.5 8.7e-07 29.5 1.1 3.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBK24914.2 - 6.6e-07 29.1 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBK24914.2 - 0.00016 21.3 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBK24914.2 - 0.028 14.6 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4404 PF14357.1 CBK24914.2 - 0.67 10.4 5.0 0.99 9.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF4090 PF13319.1 CBK24915.2 - 0.01 15.7 1.0 0.013 15.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IATP PF04568.7 CBK24915.2 - 0.013 15.5 3.9 0.015 15.3 2.3 1.3 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4460 PF14687.1 CBK24915.2 - 0.1 12.3 0.9 0.16 11.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF4432 PF14486.1 CBK24915.2 - 0.12 10.9 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) ACBP PF00887.14 CBK24916.2 - 1.5e-29 101.5 0.3 1.6e-29 101.3 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Mucin PF01456.12 CBK24917.2 - 0.0081 15.9 17.7 0.0084 15.8 12.2 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1875 PF08961.5 CBK24917.2 - 0.18 11.0 0.5 0.21 10.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) B56 PF01603.15 CBK24918.2 - 2.9e-07 29.4 0.0 4.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PPR_2 PF13041.1 CBK24919.2 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family ERp29 PF07749.7 CBK24919.2 - 0.012 16.1 0.3 0.014 15.9 0.2 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain PPR_3 PF13812.1 CBK24919.2 - 0.064 13.5 0.1 0.56 10.6 0.1 2.3 2 1 0 2 2 2 0 Pentatricopeptide repeat domain PPR PF01535.15 CBK24919.2 - 0.11 12.5 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 PPR repeat EXS PF03124.9 CBK24921.2 - 2e-56 191.5 40.2 2.7e-56 191.0 26.7 2.0 1 1 0 1 1 1 1 EXS family SPX PF03105.14 CBK24921.2 - 1.3e-32 113.7 7.1 4.3e-19 69.3 1.7 2.5 2 1 0 2 2 2 2 SPX domain VWA_2 PF13519.1 CBK24922.2 - 0.00044 20.4 0.0 0.00071 19.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Thioredoxin PF00085.15 CBK24923.2 - 8.6e-07 28.5 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBK24923.2 - 0.078 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain HECT PF00632.20 CBK24924.2 - 2.6e-61 207.4 0.1 1.1e-60 205.4 0.0 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Big_3_2 PF12245.3 CBK24924.2 - 0.028 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Pro_isomerase PF00160.16 CBK24925.2 - 9.4e-49 165.5 0.7 1.1e-48 165.3 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSP20 PF00011.16 CBK24926.2 - 6.4e-28 96.6 1.8 7.7e-28 96.3 1.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GalKase_gal_bdg PF10509.4 CBK24927.2 - 4.6e-18 64.2 0.1 1.1e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CBK24927.2 - 7.2e-15 54.9 0.0 1.9e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBK24927.2 - 1.5e-12 47.3 0.1 3.7e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF4264 PF14084.1 CBK24927.2 - 0.12 11.7 0.4 0.3 10.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) P12 PF12669.2 CBK24927.2 - 0.17 12.1 8.0 0.2 11.8 3.7 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family Aa_trans PF01490.13 CBK24928.2 - 1.6e-12 46.6 5.6 1.8e-12 46.4 3.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2165 PF09933.4 CBK24928.2 - 0.16 11.7 1.8 0.12 12.0 0.4 1.4 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) RED_N PF07808.8 CBK24929.2 - 1.7e-08 33.9 29.0 8.3e-07 28.4 20.1 2.8 1 1 0 1 1 1 1 RED-like protein N-terminal region DUF2855 PF11017.3 CBK24929.2 - 0.13 11.3 1.1 0.52 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) tRNA-synt_2b PF00587.20 CBK24930.2 - 2.7e-30 105.2 0.0 4.7e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBK24930.2 - 0.00022 21.0 0.1 0.00066 19.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain GHMP_kinases_C PF08544.8 CBK24932.2 - 7.6e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L11_N PF03946.9 CBK24933.2 - 5.5e-14 51.3 0.2 9e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBK24933.2 - 2.2e-12 46.9 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Rib_5-P_isom_A PF06026.9 CBK24933.2 - 0.068 12.4 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) STIL_N PF15253.1 CBK24933.2 - 0.14 10.8 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus IF4E PF01652.13 CBK24934.2 - 2.2e-31 108.6 0.5 2.8e-31 108.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E LRR_4 PF12799.2 CBK24935.2 - 6.2e-33 111.8 54.4 3.8e-10 39.1 1.8 5.1 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK24935.2 - 4.2e-23 80.8 32.4 4.8e-10 39.0 4.6 3.5 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBK24935.2 - 2.7e-19 66.2 36.2 0.0032 17.2 0.4 8.2 8 0 0 8 8 8 7 Leucine Rich Repeat LRR_7 PF13504.1 CBK24935.2 - 1.2e-15 54.8 33.5 0.15 12.3 0.2 8.4 8 0 0 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 CBK24935.2 - 5e-08 32.2 34.2 1 9.6 0.4 8.1 8 0 0 8 8 8 5 Leucine Rich repeat FNIP PF05725.7 CBK24935.2 - 0.00026 20.8 1.3 3.7 7.5 0.9 5.0 1 1 0 1 1 1 1 FNIP Repeat LRR_9 PF14580.1 CBK24935.2 - 0.0023 17.5 10.8 0.34 10.4 1.4 2.7 1 1 1 2 2 2 2 Leucine-rich repeat RTX PF02382.10 CBK24935.2 - 0.58 8.3 2.2 0.57 8.3 0.8 1.5 1 1 1 2 2 2 0 RTX N-terminal domain Baculo_PEP_N PF04512.7 CBK24935.2 - 0.78 9.7 7.5 14 5.7 0.1 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, N terminus ADK PF00406.17 CBK24936.2 - 5.6e-59 198.3 0.0 6.8e-59 198.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBK24936.2 - 5.4e-18 64.3 0.0 1.5e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBK24936.2 - 2.3e-06 28.3 0.0 3.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBK24936.2 - 6.9e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CBK24936.2 - 0.00041 20.6 0.0 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBK24936.2 - 0.069 13.3 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 CBK24936.2 - 0.13 11.2 0.0 0.53 9.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rpr2 PF04032.11 CBK24937.2 - 1.3e-08 34.5 0.8 2.9e-08 33.4 0.6 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-like PF04071.7 CBK24937.2 - 0.034 13.8 1.1 0.062 13.0 0.8 1.4 1 0 0 1 1 1 0 Cysteine-rich small domain TMEM190 PF15431.1 CBK24937.2 - 0.045 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 Myotub-related PF06602.9 CBK24939.2 - 3.3e-108 361.6 0.0 4e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 CBK24939.2 - 0.00088 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBK24939.2 - 0.025 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Laminin_G_3 PF13385.1 CBK24940.2 - 2.1e-06 28.0 1.3 3.2e-06 27.4 0.9 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ribosomal_S24e PF01282.14 CBK24942.2 - 5.5e-26 90.1 0.0 8.5e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e CDC45 PF02724.9 CBK24943.2 - 1.1e-105 354.0 20.0 2.7e-66 223.9 13.4 3.1 1 1 1 2 2 2 2 CDC45-like protein Histone PF00125.19 CBK24944.2 - 8e-29 99.5 1.5 1.3e-28 98.9 1.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBK24944.2 - 0.01 15.9 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S TAF PF02969.12 CBK24944.2 - 0.093 12.6 0.5 0.2 11.6 0.3 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBK24944.2 - 0.17 12.0 0.6 0.37 10.8 0.4 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3782 PF12644.2 CBK24944.2 - 0.18 11.6 1.3 0.32 10.8 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) zf-C3HC4_3 PF13920.1 CBK24945.2 - 0.00017 21.1 4.8 0.00032 20.2 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C4_ClpX PF06689.8 CBK24945.2 - 0.028 13.9 5.5 0.053 13.0 3.8 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger zf-RING_5 PF14634.1 CBK24945.2 - 0.053 13.2 6.1 0.11 12.2 4.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.1 CBK24945.2 - 0.058 12.9 3.4 0.14 11.7 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 CBK24945.2 - 0.33 11.0 7.9 0.69 9.9 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBK24945.2 - 0.58 10.0 5.8 1.1 9.1 4.0 1.5 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.22 CBK24946.2 - 1.9e-56 187.7 6.4 3.9e-23 80.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CBK24947.2 - 1.4e-25 89.9 0.0 6.9e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK24947.2 - 2.6e-08 33.2 0.0 3.2e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.22 CBK24948.2 - 1.1e-45 153.2 4.5 9.1e-18 63.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 CBK24949.2 - 4.1e-31 106.4 0.0 3.1e-17 61.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK24949.2 - 4.9e-21 74.4 0.0 1.3e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK24949.2 - 1.8e-14 53.3 0.0 3.3e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBK24949.2 - 0.00095 18.9 9.3 0.022 14.6 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBK24949.2 - 0.082 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 CBK24949.2 - 1.2 8.7 46.6 3.7 7.2 32.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) SprA-related PF12118.3 CBK24949.2 - 1.3 8.2 34.7 1.9 7.7 24.0 1.2 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.6 CBK24949.2 - 2.2 7.7 24.4 5.1 6.5 16.5 1.9 2 0 0 2 2 2 0 PPP4R2 RR_TM4-6 PF06459.7 CBK24949.2 - 8.7 6.1 20.6 12 5.6 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 CBK24949.2 - 8.8 5.7 23.5 16 4.9 16.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CTP_transf_1 PF01148.15 CBK24950.2 - 8.9e-11 41.9 3.5 1.1e-10 41.5 2.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF1576 PF07613.6 CBK24950.2 - 0.067 12.7 3.0 0.078 12.4 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1576) adh_short PF00106.20 CBK24953.2 - 5.4e-32 110.9 0.0 7.5e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBK24953.2 - 3.2e-26 92.5 0.0 4.1e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBK24953.2 - 1.8e-10 40.8 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBK24953.2 - 0.0029 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CBK24953.2 - 0.0087 15.2 0.0 0.016 14.3 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) DUF637 PF04830.8 CBK24953.2 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) Mito_carr PF00153.22 CBK24954.2 - 1.8e-35 120.4 5.1 5.4e-18 64.4 0.0 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein DAD PF02109.11 CBK24955.2 - 1.4e-32 112.0 7.2 1.5e-32 111.9 5.0 1.0 1 0 0 1 1 1 1 DAD family MNHE PF01899.11 CBK24955.2 - 0.095 12.3 0.7 0.13 11.9 0.5 1.1 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit ABC_tran PF00005.22 CBK24956.2 - 3.2e-73 244.4 2.5 9.8e-38 129.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CBK24956.2 - 2.1e-20 73.2 16.6 2.1e-20 73.2 11.5 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBK24956.2 - 8.4e-17 62.0 2.6 0.015 15.2 0.0 5.1 3 2 1 5 5 5 4 AAA domain AAA_16 PF13191.1 CBK24956.2 - 2.4e-12 47.2 0.0 1.3e-05 25.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBK24956.2 - 6.1e-12 45.8 1.8 0.00045 20.3 0.3 4.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 CBK24956.2 - 2.8e-09 37.2 0.7 0.00029 21.0 0.0 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CBK24956.2 - 3.5e-09 36.0 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBK24956.2 - 3.8e-09 36.2 2.7 8.6e-05 22.0 0.1 3.6 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBK24956.2 - 5.2e-09 35.6 12.5 0.00089 18.5 0.0 4.4 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBK24956.2 - 6.1e-09 35.2 0.2 0.0039 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBK24956.2 - 7.6e-09 36.4 1.3 0.0062 17.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CBK24956.2 - 7e-08 32.2 1.6 0.098 12.0 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain ABC_ATPase PF09818.4 CBK24956.2 - 9e-08 31.1 2.2 0.00092 17.9 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CBK24956.2 - 1.1e-07 31.6 3.8 0.0025 17.7 0.5 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBK24956.2 - 2.5e-07 30.4 0.4 0.06 12.9 0.0 4.5 3 2 1 4 4 4 2 AAA domain AAA_5 PF07728.9 CBK24956.2 - 2.3e-06 27.3 0.5 0.48 10.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CBK24956.2 - 9.6e-06 26.0 14.4 0.016 15.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CBK24956.2 - 2.1e-05 24.8 10.5 0.0094 16.2 0.0 4.6 4 1 1 5 5 4 2 AAA domain RNA_helicase PF00910.17 CBK24956.2 - 4.3e-05 23.6 0.2 0.91 9.7 0.0 4.0 4 0 0 4 4 4 1 RNA helicase MobB PF03205.9 CBK24956.2 - 4.9e-05 23.0 0.1 0.61 9.7 0.0 3.2 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CBK24956.2 - 5e-05 22.1 15.5 0.01 14.5 0.0 3.2 3 0 0 3 3 2 2 G-protein alpha subunit Raftlin PF15250.1 CBK24956.2 - 8.6e-05 21.2 6.4 0.00014 20.5 4.4 1.2 1 0 0 1 1 1 1 Raftlin MMR_HSR1 PF01926.18 CBK24956.2 - 9.6e-05 22.3 0.1 0.44 10.5 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 CBK24956.2 - 0.00026 20.8 0.2 0.36 10.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBK24956.2 - 0.00027 19.8 0.1 0.14 10.9 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 CBK24956.2 - 0.00049 19.2 0.0 0.16 11.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 CBK24956.2 - 0.00052 20.4 0.0 0.54 10.7 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 CBK24956.2 - 0.00057 19.5 0.3 1.6 8.5 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 CBK24956.2 - 0.0014 18.1 0.5 5.5 6.3 0.0 3.9 5 0 0 5 5 3 0 IstB-like ATP binding protein AAA_14 PF13173.1 CBK24956.2 - 0.0014 18.4 0.0 1.9 8.3 0.0 3.3 3 1 0 4 4 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBK24956.2 - 0.002 17.6 0.0 0.074 12.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CBK24956.2 - 0.0031 17.0 0.4 0.35 10.3 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 CBK24956.2 - 0.0032 16.2 0.0 0.26 10.0 0.0 2.5 2 0 0 2 2 2 1 ArgK protein Ycf1 PF05758.7 CBK24956.2 - 0.0035 15.1 0.4 0.0054 14.5 0.3 1.2 1 0 0 1 1 1 1 Ycf1 DUF87 PF01935.12 CBK24956.2 - 0.0041 16.9 6.6 0.19 11.5 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF1510 PF07423.6 CBK24956.2 - 0.0053 16.1 11.2 0.0053 16.1 7.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Rad17 PF03215.10 CBK24956.2 - 0.0056 15.4 0.0 0.39 9.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 CBK24956.2 - 0.0073 15.7 0.0 3.8 6.9 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CBK24956.2 - 0.011 15.8 0.0 6.3 6.8 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 CBK24956.2 - 0.011 14.7 0.2 0.086 11.8 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 CBK24956.2 - 0.012 15.2 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CBK24956.2 - 0.013 14.7 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 CBK24956.2 - 0.015 14.7 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 CBK24956.2 - 0.016 14.8 0.1 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SE PF00437.15 CBK24956.2 - 0.032 13.1 0.1 0.13 11.0 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein CDC45 PF02724.9 CBK24956.2 - 0.039 12.0 10.1 0.069 11.1 7.0 1.4 1 0 0 1 1 1 0 CDC45-like protein PRK PF00485.13 CBK24956.2 - 0.041 13.4 5.2 0.64 9.5 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 CBK24956.2 - 0.043 13.7 0.2 3 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.5 CBK24956.2 - 0.32 11.0 21.0 0.72 9.8 11.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.11 CBK24956.2 - 0.32 10.3 6.6 0.74 9.1 4.6 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 GAGA_bind PF06217.7 CBK24956.2 - 0.58 10.0 6.5 2.1 8.2 4.2 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Tim54 PF11711.3 CBK24956.2 - 2.3 6.7 9.8 4 5.9 6.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3987 PF13148.1 CBK24956.2 - 3 6.3 20.0 1.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) RR_TM4-6 PF06459.7 CBK24956.2 - 3.5 7.4 15.4 6.1 6.6 10.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 KH_1 PF00013.24 CBK24957.2 - 3.5e-48 161.0 13.0 2.6e-08 33.3 0.5 10.0 10 0 0 10 10 10 7 KH domain KH_3 PF13014.1 CBK24957.2 - 2.9e-27 93.7 1.8 0.00016 21.2 0.0 8.1 8 0 0 8 8 8 7 KH domain SLS PF14611.1 CBK24957.2 - 1.7e-15 57.0 10.3 0.013 14.9 0.0 7.7 2 2 6 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 CBK24957.2 - 2e-10 40.0 14.9 0.021 14.4 0.0 6.1 6 1 0 6 6 6 3 KH domain Acyl_transf_1 PF00698.16 CBK24957.2 - 2e-05 24.0 8.1 0.0016 17.8 0.8 2.9 2 1 0 2 2 2 2 Acyl transferase domain KH_4 PF13083.1 CBK24957.2 - 0.00031 20.3 0.1 0.088 12.4 0.0 4.3 4 0 0 4 4 4 1 KH domain Secretin_N PF03958.12 CBK24957.2 - 0.0015 18.6 4.9 10 6.4 0.1 5.6 5 1 1 6 6 6 1 Bacterial type II/III secretion system short domain KH_5 PF13184.1 CBK24957.2 - 0.0029 17.3 9.1 0.51 10.1 0.2 5.1 6 0 0 6 6 6 1 NusA-like KH domain DUF1828 PF08861.5 CBK24957.2 - 0.025 14.1 2.3 27 4.5 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function DUF1828 BRF1 PF07741.8 CBK24957.2 - 2.6 8.3 11.7 0.51 10.5 4.7 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DNA_pol3_beta_3 PF02768.10 CBK24957.2 - 3.2 7.3 14.1 3.9 7.0 0.2 4.4 3 2 2 5 5 5 0 DNA polymerase III beta subunit, C-terminal domain KH_1 PF00013.24 CBK24958.2 - 1.1e-14 53.7 0.7 3.3e-11 42.6 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBK24958.2 - 2.3e-05 23.9 3.0 6.5e-05 22.4 0.1 3.2 3 2 1 4 4 4 1 KH domain KH_2 PF07650.12 CBK24958.2 - 0.0004 19.8 2.5 0.0016 17.9 1.1 2.6 1 1 1 2 2 2 1 KH domain KH_5 PF13184.1 CBK24958.2 - 0.0011 18.6 4.5 0.068 12.9 0.1 3.1 3 0 0 3 3 3 2 NusA-like KH domain Phage_HK97_TLTM PF06120.6 CBK24958.2 - 0.0045 16.3 3.3 0.0048 16.2 1.7 1.4 1 1 0 1 1 1 1 Tail length tape measure protein MIS13 PF08202.6 CBK24958.2 - 0.005 15.9 6.5 0.0083 15.2 4.5 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family NPV_P10 PF05531.7 CBK24958.2 - 0.19 12.0 0.9 0.98 9.7 0.1 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 CBK24958.2 - 0.5 9.9 6.7 1.4 8.5 0.1 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Syntaxin-6_N PF09177.6 CBK24958.2 - 1.5 9.2 13.2 4.6 7.7 3.0 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.13 CBK24958.2 - 5.8 5.8 12.2 3.1 6.7 5.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DNA_pol_B_2 PF03175.8 CBK24960.2 - 3.6e-09 35.8 8.7 0.0017 17.0 2.7 3.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Ribosomal_L44 PF00935.14 CBK24961.2 - 1.8e-30 104.7 12.2 3e-30 104.0 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Phage_coat PF09063.5 CBK24961.2 - 0.11 12.2 0.0 27 4.5 0.0 2.7 2 0 0 2 2 2 0 Phage PP7 coat protein AnfG_VnfG PF03139.10 CBK24961.2 - 0.92 9.3 11.3 28 4.5 0.1 4.8 4 0 0 4 4 4 0 Vanadium/alternative nitrogenase delta subunit MMtag PF10159.4 CBK24962.2 - 4.1e-12 45.9 0.9 6.2e-12 45.3 0.6 1.3 1 0 0 1 1 1 1 Kinase phosphorylation protein DUF2046 PF09755.4 CBK24962.2 - 0.027 13.3 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) A2M PF00207.17 CBK24962.2 - 0.11 12.0 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DUF563 PF04577.9 CBK24963.2 - 1.4e-25 90.4 0.1 8.4e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) HSP70 PF00012.15 CBK24964.2 - 1.9e-08 32.6 0.0 2.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MORN PF02493.15 CBK24965.2 - 0.00077 19.0 14.7 0.046 13.4 3.3 4.2 4 0 0 4 4 4 3 MORN repeat PaREP1 PF05942.6 CBK24965.2 - 0.0066 16.3 10.5 0.011 15.5 6.4 2.0 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family DDHD PF02862.12 CBK24965.2 - 2.4 7.9 6.8 3.5 7.3 4.7 1.2 1 0 0 1 1 1 0 DDHD domain Caldesmon PF02029.10 CBK24965.2 - 4 5.7 19.7 5.8 5.2 13.6 1.1 1 0 0 1 1 1 0 Caldesmon E1_DerP2_DerF2 PF02221.10 CBK24966.2 - 4.4e-14 52.8 0.0 5e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 ML domain AMP-binding PF00501.23 CBK24967.2 - 1.5e-10 40.0 0.0 5.3e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 CBK24967.2 - 2.1e-08 34.3 0.0 9.8e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.1 CBK24967.2 - 0.0002 21.3 0.7 0.00046 20.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C PF13193.1 CBK24967.2 - 0.0011 19.8 1.0 0.0021 18.9 0.7 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF605 PF04652.11 CBK24967.2 - 0.78 9.0 15.7 0.55 9.5 7.4 2.0 2 0 0 2 2 2 0 Vta1 like Neur_chan_memb PF02932.11 CBK24967.2 - 4.1 7.2 5.9 4 7.2 0.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CBK24967.2 - 7.2 4.5 8.2 8.5 4.2 2.5 2.0 2 0 0 2 2 2 0 CDC45-like protein AMP-binding PF00501.23 CBK24968.2 - 4.6e-08 31.8 0.0 6.1e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GVQW PF13900.1 CBK24969.2 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative binding domain PUF PF00806.14 CBK24970.2 - 3.2e-20 70.4 10.6 0.0031 16.8 0.0 8.0 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat bZIP_1 PF00170.16 CBK24971.2 - 4.5e-05 23.3 22.1 0.004 17.0 1.9 3.3 3 0 0 3 3 3 2 bZIP transcription factor TPR_MLP1_2 PF07926.7 CBK24971.2 - 0.0016 18.2 21.6 0.0044 16.7 14.5 1.9 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein HOOK PF05622.7 CBK24971.2 - 0.0022 15.8 15.5 0.003 15.4 10.7 1.2 1 0 0 1 1 1 1 HOOK protein Herpes_BLRF2 PF05812.7 CBK24971.2 - 0.0026 17.5 11.3 0.016 15.0 0.9 2.4 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein Filament PF00038.16 CBK24971.2 - 0.0035 16.8 20.9 0.018 14.5 14.5 2.1 1 1 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 CBK24971.2 - 0.0054 16.3 27.0 0.28 10.7 18.6 2.1 1 1 0 1 1 1 1 IncA protein AAA_13 PF13166.1 CBK24971.2 - 0.0067 14.9 10.7 0.0087 14.5 7.4 1.1 1 0 0 1 1 1 1 AAA domain GAS PF13851.1 CBK24971.2 - 0.01 15.0 20.2 0.17 11.0 8.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 CBK24971.2 - 0.015 15.0 8.6 0.015 15.0 6.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 CBK24971.2 - 0.029 14.1 21.6 0.4 10.4 1.6 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding GOLGA2L5 PF15070.1 CBK24971.2 - 0.032 12.7 14.9 0.021 13.3 8.5 1.8 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF869 PF05911.6 CBK24971.2 - 0.034 12.4 21.8 0.082 11.1 1.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF972 PF06156.8 CBK24971.2 - 0.035 14.4 21.4 0.3 11.4 1.4 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 CBK24971.2 - 0.036 13.9 20.3 0.13 12.2 7.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 CBK24971.2 - 0.042 13.9 16.3 1.9 8.6 7.3 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 CBK24971.2 - 0.072 12.9 25.9 1.5 8.6 8.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 CBK24971.2 - 0.089 13.0 25.8 0.56 10.5 1.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 CBK24971.2 - 0.094 12.3 23.6 0.75 9.3 9.9 2.4 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Myosin_tail_1 PF01576.14 CBK24971.2 - 0.1 10.2 21.5 0.055 11.1 2.5 2.0 1 1 1 2 2 2 0 Myosin tail DUF4201 PF13870.1 CBK24971.2 - 0.11 11.9 18.4 1.7 8.0 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TSC22 PF01166.13 CBK24971.2 - 0.11 12.4 0.6 0.11 12.4 0.4 3.9 2 1 1 3 3 2 0 TSC-22/dip/bun family Taxilin PF09728.4 CBK24971.2 - 0.12 11.4 19.7 0.84 8.6 13.5 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Mod_r PF07200.8 CBK24971.2 - 0.14 12.0 22.4 1.1 9.1 13.1 2.9 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.5 CBK24971.2 - 0.15 12.1 14.2 0.27 11.3 5.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 CBK24971.2 - 0.15 11.5 18.9 1.2 8.6 1.0 3.4 2 1 1 3 3 3 0 Septum formation initiator tRNA-synt_2c PF01411.14 CBK24971.2 - 0.16 10.2 6.3 0.21 9.8 4.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Mnd1 PF03962.10 CBK24971.2 - 0.17 11.5 18.7 0.36 10.4 1.8 2.3 1 1 1 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 CBK24971.2 - 0.19 9.5 15.8 0.1 10.4 5.7 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WEMBL PF05701.6 CBK24971.2 - 0.21 9.9 18.9 1.1 7.6 13.1 1.8 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ATG16 PF08614.6 CBK24971.2 - 0.22 11.3 22.3 1.2 8.9 8.2 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HrpA_pilin PF09589.5 CBK24971.2 - 0.24 11.8 3.3 1.1 9.7 2.3 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein DUF1204 PF06721.6 CBK24971.2 - 0.25 10.5 6.7 2.6 7.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) DASH_Spc19 PF08287.6 CBK24971.2 - 0.29 10.7 15.2 1.1 8.8 4.7 2.5 1 1 1 2 2 2 0 Spc19 TBPIP PF07106.8 CBK24971.2 - 0.29 10.6 22.0 0.67 9.4 1.6 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PRP1_N PF06424.7 CBK24971.2 - 0.42 10.9 7.0 1.2 9.4 4.6 2.0 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Misat_Tub_SegII PF10644.4 CBK24971.2 - 0.44 10.6 7.1 0.11 12.5 0.4 2.3 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain OmpH PF03938.9 CBK24971.2 - 0.54 10.1 14.4 1.4 8.8 10.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) COG2 PF06148.6 CBK24971.2 - 0.59 9.9 14.4 1 9.2 4.5 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_Maf PF03131.12 CBK24971.2 - 0.63 10.3 14.8 0.73 10.1 0.5 3.3 2 1 1 3 3 3 0 bZIP Maf transcription factor DivIVA PF05103.8 CBK24971.2 - 0.74 9.8 17.8 2.1 8.3 0.5 2.8 2 1 0 2 2 2 0 DivIVA protein DUF1664 PF07889.7 CBK24971.2 - 0.87 9.3 8.5 4.9 6.9 2.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Orthopox_A5L PF06193.6 CBK24971.2 - 1 9.3 15.8 10 6.0 11.0 2.2 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like Ax_dynein_light PF10211.4 CBK24971.2 - 1 9.1 20.3 1.4 8.7 3.0 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.17 CBK24971.2 - 1.1 9.2 13.9 4.3 7.3 7.9 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 CBK24971.2 - 1.1 7.5 15.2 0.55 8.5 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 CBK24971.2 - 1.2 9.1 21.9 1.6 8.7 7.9 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3186 PF11382.3 CBK24971.2 - 1.3 8.0 9.8 0.17 11.0 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) TMPIT PF07851.8 CBK24971.2 - 2.1 7.3 13.7 0.34 9.9 3.7 2.0 2 0 0 2 2 2 0 TMPIT-like protein Macoilin PF09726.4 CBK24971.2 - 2.6 6.2 19.8 0.11 10.7 6.6 1.9 1 1 0 2 2 2 0 Transmembrane protein DUF4337 PF14235.1 CBK24971.2 - 2.7 7.8 11.7 2.1 8.1 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Rab5-bind PF09311.6 CBK24971.2 - 2.8 7.8 20.1 2.8e+02 1.2 13.6 2.8 1 1 0 1 1 1 0 Rabaptin-like protein AAA_23 PF13476.1 CBK24971.2 - 2.8 8.2 15.1 4.3 7.6 10.5 1.4 1 1 0 1 1 1 0 AAA domain Mto2_bdg PF12808.2 CBK24971.2 - 3.1 7.9 9.6 4.3 7.5 1.6 2.9 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cep57_CLD_2 PF14197.1 CBK24971.2 - 3.5 7.6 20.5 1.2 9.1 1.9 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 CBK24971.2 - 3.8 7.2 19.9 0.65 9.7 1.6 4.3 3 3 1 5 5 4 0 Homeobox associated leucine zipper DUF3450 PF11932.3 CBK24971.2 - 4.1 6.5 16.6 7 5.8 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.6 CBK24971.2 - 4.3 4.7 12.2 6.2 4.2 8.4 1.1 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 CBK24971.2 - 4.9 6.1 23.4 0.6 9.0 8.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2935 PF11155.3 CBK24971.2 - 5.1 7.2 9.7 67 3.5 6.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Syntaxin PF00804.20 CBK24971.2 - 5.7 7.1 17.2 5.7 7.1 0.7 2.6 1 1 0 2 2 2 0 Syntaxin Rootletin PF15035.1 CBK24971.2 - 7.3 6.5 22.5 5.3 6.9 2.1 2.3 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion YlqD PF11068.3 CBK24971.2 - 7.6 6.5 18.2 1.6 8.7 1.0 2.2 1 1 1 2 2 2 0 YlqD protein DUF3496 PF12001.3 CBK24971.2 - 7.6 6.8 14.2 0.72 10.1 5.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3496) Cluap1 PF10234.4 CBK24971.2 - 8.5 5.4 19.9 5.3 6.1 6.8 2.1 1 1 0 2 2 2 0 Clusterin-associated protein-1 Kinesin-relat_1 PF12711.2 CBK24971.2 - 8.8 6.8 19.3 1.3 9.5 1.2 3.2 1 1 1 2 2 2 0 Kinesin motor Kinetocho_Slk19 PF12709.2 CBK24971.2 - 9.1 6.4 20.0 1 9.4 1.2 3.3 2 1 1 3 3 3 0 Central kinetochore-associated HAUS6_N PF14661.1 CBK24971.2 - 9.2 5.5 16.0 2.7 7.3 3.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FliD_N PF02465.13 CBK24971.2 - 9.3 6.6 12.2 3 8.2 3.3 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF607 PF04678.8 CBK24971.2 - 9.7 6.0 9.4 5.2 6.9 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Spc7 PF08317.6 CBK24972.2 - 3.4e-05 22.6 24.5 3.4e-05 22.6 17.0 2.8 2 1 1 3 3 3 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 CBK24972.2 - 0.00016 19.6 46.3 0.00016 19.6 32.1 2.2 2 1 0 2 2 2 1 Myosin tail DivIC PF04977.10 CBK24972.2 - 0.0012 18.2 4.2 0.0012 18.2 2.9 6.5 3 2 3 7 7 7 1 Septum formation initiator Cortex-I_coil PF09304.5 CBK24972.2 - 0.054 13.5 54.2 0.12 12.4 8.6 4.0 1 1 2 4 4 4 0 Cortexillin I, coiled coil IncA PF04156.9 CBK24972.2 - 0.28 10.7 66.8 0.024 14.2 23.5 3.7 2 1 2 4 4 4 0 IncA protein CRT10 PF08728.5 CBK24972.2 - 0.58 8.0 12.6 0.7 7.8 8.7 1.1 1 0 0 1 1 1 0 CRT10 LPP PF04728.8 CBK24972.2 - 1.3 8.8 8.9 3.2 7.6 0.0 4.6 3 1 2 5 5 5 0 Lipoprotein leucine-zipper Troponin PF00992.15 CBK24972.2 - 1.7 8.7 36.9 2.3 8.2 7.4 3.9 1 1 2 3 3 3 0 Troponin TMF_TATA_bd PF12325.3 CBK24972.2 - 2 8.1 54.8 1.1 8.9 11.3 5.0 2 1 3 5 5 4 0 TATA element modulatory factor 1 TATA binding ERM PF00769.14 CBK24972.2 - 2.5 7.5 58.6 0.034 13.6 16.4 4.1 2 1 2 4 4 4 0 Ezrin/radixin/moesin family Atg14 PF10186.4 CBK24972.2 - 3.8 6.3 47.4 0.16 10.8 3.5 3.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CBK24972.2 - 6.2 6.7 61.5 0.17 11.8 6.0 4.7 2 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CBK24972.2 - 7.6 5.4 60.4 0.39 9.7 10.7 3.7 2 1 2 4 4 4 0 Autophagy protein Apg6 Mnd1 PF03962.10 CBK24973.2 - 8.2e-05 22.3 5.1 8.2e-05 22.3 3.6 3.6 1 1 3 4 4 4 1 Mnd1 family DUF2959 PF11172.3 CBK24973.2 - 0.0043 16.8 1.0 0.0043 16.8 0.7 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2959) ATG16 PF08614.6 CBK24973.2 - 0.0052 16.6 45.4 0.016 15.0 14.8 3.2 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CBK24973.2 - 0.02 14.7 47.8 0.17 11.7 0.4 4.8 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 CBK24973.2 - 0.12 10.8 22.2 0.21 9.9 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Miro PF08477.8 CBK24973.2 - 0.14 12.6 0.6 0.5 10.8 0.2 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_13 PF13166.1 CBK24973.2 - 0.92 7.8 25.5 14 4.0 17.6 2.1 1 1 0 1 1 1 0 AAA domain FliJ PF02050.11 CBK24973.2 - 2.3 8.2 43.5 0.21 11.6 2.0 4.1 3 1 1 4 4 4 0 Flagellar FliJ protein DUF241 PF03087.9 CBK24973.2 - 2.3 7.6 23.4 4.8 6.6 0.3 3.2 2 1 1 3 3 3 0 Arabidopsis protein of unknown function DUF3584 PF12128.3 CBK24973.2 - 3.9 4.6 43.9 1.8 5.8 10.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.1 CBK24973.2 - 7.1 5.7 39.1 1.2 8.2 15.4 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 CBK24973.2 - 9.5 4.5 36.6 0.23 9.9 7.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1811 PF08838.5 CBK24973.2 - 9.7 6.2 9.7 0.65 9.9 2.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1811) SAC3_GANP PF03399.11 CBK24975.2 - 5.5e-44 150.1 3.9 7.3e-44 149.7 2.7 1.0 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBK24975.2 - 4.9e-06 26.3 0.1 9.1e-05 22.2 0.1 2.3 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 COX5A PF02284.11 CBK24975.2 - 0.026 14.4 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va DUF2092 PF09865.4 CBK24976.2 - 0.058 12.4 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) mRNA_cap_enzyme PF01331.14 CBK24977.2 - 1.2e-16 60.9 0.0 1.4e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CBK24977.2 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DUF2737 PF10930.3 CBK24978.2 - 1.6 8.3 3.9 15 5.2 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2737) RICTOR_N PF14664.1 CBK24979.2 - 9.6e-43 146.1 13.3 1.8e-42 145.3 9.2 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.1 CBK24979.2 - 1.5e-13 50.4 0.0 4.9e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 HSP70 PF00012.15 CBK24982.2 - 4.8e-17 61.1 0.0 6.5e-17 60.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK24982.2 - 0.0026 16.3 0.1 0.25 9.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.15 CBK24983.2 - 1.9e-09 35.9 0.0 2.1e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Nicastrin PF05450.10 CBK24984.2 - 0.024 13.9 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Nicastrin DUF4243 PF14027.1 CBK24985.2 - 0.065 12.6 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Aldolase_II PF00596.16 CBK24986.2 - 1e-30 106.6 0.2 1.5e-28 99.6 0.1 2.2 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SRP54 PF00448.17 CBK24988.2 - 4.8e-77 257.8 0.1 9.7e-77 256.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CBK24988.2 - 9.7e-20 70.7 4.8 9.7e-20 70.7 3.3 3.2 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 CBK24988.2 - 8.5e-16 57.8 1.2 1.7e-15 56.8 0.9 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CBK24988.2 - 2.8e-06 26.9 0.2 1.4e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CBK24988.2 - 5.3e-06 26.1 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CBK24988.2 - 5.4e-05 23.1 0.0 0.00015 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CBK24988.2 - 6.6e-05 22.1 0.8 0.025 13.8 0.1 2.6 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit CbiA PF01656.18 CBK24988.2 - 0.00097 18.5 0.0 0.0055 16.1 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain YopR_core PF09025.5 CBK24988.2 - 0.0012 18.9 0.3 0.0027 17.7 0.2 1.6 1 0 0 1 1 1 1 YopR Core Miro PF08477.8 CBK24988.2 - 0.0017 18.8 0.1 2 8.9 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein DUF2209 PF09974.4 CBK24988.2 - 0.0033 17.5 0.3 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2209) AAA_16 PF13191.1 CBK24988.2 - 0.004 17.1 0.0 0.012 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain ArgK PF03308.11 CBK24988.2 - 0.0053 15.5 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 CBK24988.2 - 0.013 16.3 0.0 0.035 14.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 CBK24988.2 - 0.014 15.0 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 CBK24988.2 - 0.015 14.9 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.1 CBK24988.2 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBK24988.2 - 0.026 14.6 0.0 0.091 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CBK24988.2 - 0.031 13.4 0.2 5.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBK24988.2 - 0.049 12.7 0.1 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.10 CBK24988.2 - 0.085 12.6 0.2 0.2 11.4 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CBK24988.2 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IFRD PF05004.8 CBK24989.2 - 4.8e-15 55.4 6.6 8e-15 54.7 4.6 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TAN PF11640.3 CBK24989.2 - 0.00059 19.5 0.8 0.0029 17.3 0.1 2.2 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair RIX1 PF08167.7 CBK24989.2 - 0.046 13.3 1.5 0.065 12.9 0.4 1.8 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis Apyrase PF06079.6 CBK24990.2 - 3.1e-109 364.6 1.7 4.2e-109 364.1 1.2 1.2 1 0 0 1 1 1 1 Apyrase LSM PF01423.17 CBK24991.2 - 9.7e-18 63.4 5.4 1.2e-17 63.2 3.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBK24991.2 - 2.8e-06 27.1 0.2 3.4e-06 26.8 0.2 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_C23 PF05379.6 CBK24991.2 - 0.11 12.5 0.2 0.16 11.9 0.1 1.4 1 1 0 1 1 1 0 Carlavirus endopeptidase HLH PF00010.21 CBK24993.2 - 0.00015 21.4 0.2 0.00034 20.2 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF724 PF05266.9 CBK24993.2 - 0.081 12.5 1.2 0.14 11.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Metallophos PF00149.23 CBK24994.2 - 1.5e-40 138.7 0.1 1.9e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK24994.2 - 0.00056 19.7 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L2_C PF03947.13 CBK24995.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK24995.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Presenilin PF01080.12 CBK24996.2 - 9.8e-57 192.5 28.2 3.2e-37 128.3 12.1 2.0 2 0 0 2 2 2 2 Presenilin T2SF PF00482.18 CBK24996.2 - 0.043 13.7 5.7 0.052 13.4 0.4 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Cyclin_N PF00134.18 CBK24997.2 - 7.8e-09 35.1 1.0 1.4e-08 34.3 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MipA PF06629.7 CBK24998.2 - 0.026 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 MltA-interacting protein MipA Radical_SAM PF04055.16 CBK24998.2 - 0.026 14.6 0.2 0.037 14.2 0.1 1.3 1 0 0 1 1 1 0 Radical SAM superfamily DYW_deaminase PF14432.1 CBK24998.2 - 0.039 13.9 1.1 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases BATS PF06968.8 CBK24999.2 - 0.072 12.9 0.1 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain Diacid_rec PF05651.8 CBK24999.2 - 0.092 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition Ribosomal_L18ae PF01775.12 CBK25000.2 - 1e-41 141.6 0.4 1.6e-41 141.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ldh_1_N PF00056.18 CBK25001.2 - 1.1e-37 128.9 0.0 2.2e-37 128.0 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBK25001.2 - 3.4e-33 114.8 0.0 4.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain THF_DHG_CYH_C PF02882.14 CBK25001.2 - 0.0072 15.4 0.0 0.036 13.1 0.0 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 CBK25001.2 - 0.0073 16.6 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CBK25001.2 - 0.033 13.4 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CBK25001.2 - 0.049 12.3 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-AN1 PF01428.11 CBK25002.2 - 5e-19 67.8 25.2 9e-12 44.6 5.8 3.0 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CBK25002.2 - 9.2e-05 22.5 5.1 9.2e-05 22.5 3.5 3.1 2 1 1 3 3 3 2 Tc5 transposase C-terminal domain FYVE PF01363.16 CBK25002.2 - 0.041 13.7 18.9 0.045 13.6 3.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC PF07967.8 CBK25002.2 - 0.13 11.9 15.2 0.14 11.8 1.3 3.1 1 1 1 3 3 3 0 C3HC zinc finger-like IBR PF01485.16 CBK25002.2 - 0.47 10.3 26.7 0.088 12.6 6.0 3.5 2 2 1 3 3 3 0 IBR domain zf-FCS PF06467.9 CBK25002.2 - 0.69 9.6 17.8 0.91 9.2 1.4 3.6 2 1 2 4 4 4 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.2 CBK25002.2 - 2.6 7.9 16.7 8.7e+02 -0.2 11.6 2.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RAG1 PF10426.4 CBK25002.2 - 4.8 7.2 12.4 1.5 8.8 0.5 3.7 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain DUF2180 PF09947.4 CBK25002.2 - 5.4 6.8 14.5 11 5.8 2.7 3.1 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) DUF1700 PF08006.6 CBK25003.2 - 4.7 6.4 6.1 7.6 5.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) HATPase_c_3 PF13589.1 CBK25004.2 - 5.3e-15 55.2 0.0 9.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBK25004.2 - 1.3e-10 41.0 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 CBK25004.2 - 0.00055 19.5 0.2 0.00099 18.7 0.1 1.4 1 0 0 1 1 1 1 GHKL domain UBN2_2 PF14227.1 CBK25004.2 - 0.065 12.7 0.6 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type ubiquitin PF00240.18 CBK25005.2 - 1.1e-34 117.6 0.7 2.3e-34 116.6 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CBK25005.2 - 2.7e-24 84.7 2.8 5.2e-24 83.7 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CBK25005.2 - 1.9e-19 69.0 0.7 1.9e-19 69.0 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBK25005.2 - 1.3e-05 25.3 0.8 3.9e-05 23.8 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBK25005.2 - 0.00031 20.4 0.4 0.00055 19.6 0.3 1.5 1 1 1 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBK25005.2 - 0.00032 20.5 0.8 0.00067 19.5 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK25005.2 - 0.0017 18.4 0.6 0.0025 17.9 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 CBK25005.2 - 0.0045 15.3 0.8 0.55 8.4 0.1 2.1 2 0 0 2 2 2 2 Plexin cytoplasmic RasGAP domain zf-ribbon_3 PF13248.1 CBK25005.2 - 0.0086 15.2 3.0 0.018 14.2 2.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBK25005.2 - 0.022 14.5 0.3 0.037 13.8 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 CBK25005.2 - 0.06 13.2 1.1 0.099 12.5 0.8 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CBK25005.2 - 0.14 12.2 1.5 0.16 12.0 0.4 1.7 2 1 0 2 2 1 0 Protein of unknown function (DUF2870) zinc_ribbon_4 PF13717.1 CBK25005.2 - 0.61 9.8 2.8 5.7 6.7 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBK25005.2 - 1.1 8.8 4.0 12 5.4 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK25005.2 - 2.4 7.8 5.3 6.1 6.5 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain HSP70 PF00012.15 CBK25006.2 - 1.2e-07 30.1 0.0 3.1e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein Fra10Ac1 PF09725.4 CBK25006.2 - 0.15 12.1 1.7 0.3 11.1 1.2 1.6 1 1 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 zf-RING_2 PF13639.1 CBK25007.2 - 1.3e-13 50.5 5.3 2.8e-13 49.4 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBK25007.2 - 5e-11 42.5 3.2 9.8e-11 41.6 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBK25007.2 - 2.2e-09 36.8 3.0 5.2e-09 35.6 2.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBK25007.2 - 2.9e-09 36.4 5.1 6.3e-09 35.4 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBK25007.2 - 4.8e-07 29.3 7.9 1.1e-06 28.2 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBK25007.2 - 7.3e-07 29.1 5.4 4.9e-06 26.4 4.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBK25007.2 - 1.9e-05 24.4 3.4 6.9e-05 22.6 2.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBK25007.2 - 0.00036 20.0 5.4 0.00076 19.0 3.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBK25007.2 - 0.00042 19.9 3.5 0.00094 18.8 2.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 CBK25007.2 - 0.036 14.1 5.2 0.079 13.0 3.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CBK25007.2 - 0.038 13.9 5.7 0.14 12.1 3.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 CBK25007.2 - 0.066 13.0 0.4 0.17 11.7 0.3 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 CBK25007.2 - 0.1 12.3 4.9 0.19 11.4 3.4 1.5 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 CBK25008.2 - 2e-09 36.9 7.1 2e-09 36.9 4.9 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CBK25008.2 - 0.004 16.4 4.0 0.0081 15.4 2.8 1.5 1 0 0 1 1 1 1 PHD-finger Nipped-B_C PF12830.2 CBK25009.2 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.5 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus Pex14_N PF04695.8 CBK25009.2 - 0.046 13.7 1.8 0.067 13.2 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YdjC PF04794.7 CBK25009.2 - 0.15 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 YdjC-like protein Retinal PF15449.1 CBK25009.2 - 1.5 6.4 19.4 1.8 6.1 13.5 1.0 1 0 0 1 1 1 0 Retinal protein Pol_alpha_B_N PF08418.5 CBK25009.2 - 2.9 7.3 8.2 3.8 6.9 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 CBK25009.2 - 9.8 5.4 18.5 12 5.1 12.8 1.1 1 0 0 1 1 1 0 Vta1 like He_PIG PF05345.7 CBK25010.2 - 0.0006 19.7 1.9 0.0006 19.7 1.3 3.8 3 1 0 3 3 3 1 Putative Ig domain PA14 PF07691.7 CBK25010.2 - 0.0012 18.4 0.1 0.0023 17.5 0.0 1.6 2 0 0 2 2 2 1 PA14 domain He_PIG PF05345.7 CBK25011.2 - 1.9e-13 50.1 25.3 5.2e-05 23.1 3.9 5.1 4 0 0 4 4 4 3 Putative Ig domain PA14 PF07691.7 CBK25011.2 - 6.7e-10 38.7 0.2 1.3e-08 34.5 0.1 2.4 2 0 0 2 2 2 1 PA14 domain F5_F8_type_C PF00754.20 CBK25011.2 - 9.1e-05 22.3 4.1 9.1e-05 22.3 2.9 2.3 2 0 0 2 2 2 1 F5/8 type C domain TMEM154 PF15102.1 CBK25011.2 - 0.049 13.3 0.2 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family SIT PF15330.1 CBK25011.2 - 0.068 13.3 0.7 0.24 11.5 0.3 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Pkinase PF00069.20 CBK25012.2 - 1e-80 270.6 0.1 2.2e-80 269.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25012.2 - 6e-40 136.9 0.0 9.6e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBK25012.2 - 2.4e-07 30.8 0.3 4.8e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CBK25012.2 - 7e-07 28.4 0.0 0.00054 19.0 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 CBK25012.2 - 0.00015 20.8 0.0 0.00033 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 CBK25012.2 - 0.002 18.3 0.4 0.0059 16.8 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Choline_kinase PF01633.15 CBK25012.2 - 0.01 15.4 0.0 0.03 13.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 CBK25012.2 - 0.012 15.3 0.0 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RILP PF11461.3 CBK25012.2 - 0.02 15.0 0.1 0.054 13.6 0.1 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein PH_3 PF14593.1 CBK25012.2 - 0.045 13.6 0.6 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 PH domain PH PF00169.24 CBK25013.2 - 2.4e-05 24.4 0.1 0.00056 20.0 0.0 2.4 2 0 0 2 2 2 1 PH domain WD40 PF00400.27 CBK25013.2 - 0.00053 19.7 1.7 0.0041 16.9 0.0 3.3 5 0 0 5 5 5 1 WD domain, G-beta repeat PH_9 PF15410.1 CBK25013.2 - 0.043 13.9 0.2 0.17 12.0 0.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain tRNA_anti_2 PF13742.1 CBK25013.2 - 0.05 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PQQ PF01011.16 CBK25013.2 - 0.078 12.5 0.7 1.2 8.7 0.1 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.1 CBK25013.2 - 0.66 10.3 6.0 27 5.2 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain CENP-O PF09496.5 CBK25014.2 - 2.1e-13 50.2 0.2 4.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component TPR_11 PF13414.1 CBK25015.2 - 1.5e-11 43.7 0.0 7.5e-09 35.1 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBK25015.2 - 4.7e-10 38.5 0.0 1.6e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBK25015.2 - 2.9e-09 36.1 0.0 1.5e-06 27.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK25015.2 - 3.9e-06 26.7 0.0 0.005 16.7 0.0 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK25015.2 - 4.6e-06 26.0 0.1 0.00057 19.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25015.2 - 0.00015 21.6 0.1 0.017 15.2 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBK25015.2 - 0.0018 18.1 0.1 0.0057 16.5 0.0 1.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CBK25015.2 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_28 PF02636.12 CBK25015.2 - 0.023 14.1 0.0 0.099 12.0 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_14 PF13428.1 CBK25015.2 - 0.031 14.9 0.0 4.4 8.2 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 CBK25015.2 - 0.06 11.9 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Methyltransf_32 PF13679.1 CBK25015.2 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1391 PF07151.7 CBK25016.2 - 0.052 13.0 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Sas10_Utp3 PF04000.10 CBK25017.2 - 6.2e-14 51.9 1.8 6.2e-14 51.9 1.3 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family V-SNARE_C PF12352.3 CBK25018.2 - 7.6e-11 41.9 1.1 1e-10 41.4 0.8 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Orthopox_A5L PF06193.6 CBK25018.2 - 0.07 13.0 1.2 0.079 12.9 0.8 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF892 PF05974.7 CBK25018.2 - 0.11 12.3 1.9 0.26 11.1 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF892) SNARE PF05739.14 CBK25018.2 - 0.62 9.8 6.1 1.3 8.7 2.1 2.3 1 1 1 2 2 2 0 SNARE domain Flagellin_N PF00669.15 CBK25018.2 - 0.89 9.3 5.7 6.7 6.4 4.0 1.8 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region Vac14_Fig4_bd PF11916.3 CBK25020.2 - 1.6e-17 63.2 0.1 3.6e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding DUF2454 PF10521.4 CBK25020.2 - 0.0017 17.3 0.3 1.2 8.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 CBK25020.2 - 0.0022 18.3 0.6 0.57 10.6 0.0 3.5 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.9 CBK25020.2 - 0.0041 15.9 2.8 0.019 13.7 0.2 2.5 2 1 0 2 2 2 1 Dopey, N-terminal ParcG PF10274.4 CBK25020.2 - 0.0081 16.0 3.3 0.039 13.8 1.2 2.5 2 1 1 3 3 3 1 Parkin co-regulated protein HEAT_2 PF13646.1 CBK25020.2 - 0.011 16.0 0.0 19 5.6 0.0 3.6 2 2 0 3 3 3 0 HEAT repeats Utp21 PF04192.7 CBK25020.2 - 0.021 13.9 0.5 0.15 11.1 0.0 2.4 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain CLASP_N PF12348.3 CBK25020.2 - 0.022 14.1 2.0 0.38 10.0 0.1 2.5 2 1 0 2 2 2 0 CLASP N terminal HEAT PF02985.17 CBK25020.2 - 0.03 14.3 2.2 51 4.3 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.2 CBK25021.2 - 5.1e-26 90.8 0.3 7.9e-26 90.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CBK25021.2 - 3.8e-09 35.8 0.0 4.6e-05 23.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 CBK25021.2 - 0.00025 19.5 0.0 0.00028 19.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBK25021.2 - 0.00095 19.0 0.2 0.0044 16.8 0.1 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBK25021.2 - 0.0015 18.9 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.1 CBK25021.2 - 0.01 16.0 0.0 0.025 14.8 0.0 1.9 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.18 CBK25021.2 - 0.024 14.4 0.0 9.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Paralemmin PF03285.10 CBK25021.2 - 0.057 12.8 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Paralemmin PQ-loop PF04193.9 CBK25022.2 - 4e-22 77.5 1.4 1.7e-12 46.6 0.1 3.3 5 0 0 5 5 5 2 PQ loop repeat RseA_C PF03873.8 CBK25022.2 - 0.11 12.3 0.1 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain MtN3_slv PF03083.11 CBK25022.2 - 0.19 11.5 14.9 0.39 10.6 0.9 3.1 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange zf-U1 PF06220.7 CBK25023.2 - 5.5e-16 57.8 7.2 7.1e-16 57.4 5.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CBK25023.2 - 9e-06 25.6 2.8 1.9e-05 24.6 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBK25023.2 - 0.1 12.7 3.5 0.11 12.6 2.4 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBK25023.2 - 1.9 9.0 4.0 9.6 6.7 2.8 2.1 1 1 0 1 1 1 0 C2H2-type zinc finger Peptidase_C13 PF01650.13 CBK25024.2 - 1.7e-41 142.2 0.6 9.4e-41 139.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase C13 family Acetyltransf_1 PF00583.19 CBK25025.2 - 2.1e-14 53.3 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBK25025.2 - 5.3e-10 39.3 0.5 1e-09 38.4 0.2 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBK25025.2 - 0.0007 19.4 0.0 0.00097 19.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK25025.2 - 0.0017 18.3 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBK25025.2 - 0.0045 16.7 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBK25025.2 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBK25025.2 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 CBK25025.2 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 1 0 1 1 1 0 GNAT acetyltransferase 2 MOZ_SAS PF01853.13 CBK25025.2 - 0.027 13.6 0.3 0.092 11.9 0.0 1.8 2 0 0 2 2 2 0 MOZ/SAS family Acetyltransf_3 PF13302.1 CBK25025.2 - 0.057 13.5 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PUF PF00806.14 CBK25025.2 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Acetyltransf_9 PF13527.1 CBK25025.2 - 0.13 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S26e PF01283.14 CBK25026.2 - 1.5e-44 150.8 9.0 1.7e-44 150.6 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 CBK25026.2 - 0.00058 20.1 1.3 0.023 15.0 0.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain SRP19 PF01922.12 CBK25026.2 - 0.007 16.9 0.4 0.0094 16.5 0.3 1.3 1 0 0 1 1 1 1 SRP19 protein Fer4_6 PF12837.2 CBK25026.2 - 0.017 14.9 3.0 0.059 13.2 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 CBK25026.2 - 0.018 14.8 0.8 0.23 11.3 0.2 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain RNA_pol_N PF01194.12 CBK25026.2 - 0.031 14.2 2.0 0.068 13.2 1.4 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.4 CBK25026.2 - 0.036 13.1 0.7 0.083 11.9 0.5 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Fer4_19 PF06902.6 CBK25026.2 - 0.058 13.2 0.3 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.22 CBK25026.2 - 0.069 12.7 3.5 0.086 12.4 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 CBK25026.2 - 0.36 10.8 4.1 0.48 10.4 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 CBK25026.2 - 0.56 10.2 4.0 2.5 8.1 2.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBK25026.2 - 1.1 9.5 5.5 2.9 8.2 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBK25026.2 - 5.3 7.6 8.5 1.8 9.1 2.5 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain DLIC PF05783.6 CBK25027.2 - 4e-16 58.7 0.0 5.4e-16 58.3 0.0 1.2 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF4400 PF14348.1 CBK25027.2 - 0.06 12.7 0.9 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) JAB PF01398.16 CBK25028.2 - 1.2e-12 47.5 0.1 3.4e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBK25028.2 - 4.9e-10 39.5 0.5 9e-10 38.6 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Put_Phosphatase PF06888.7 CBK25028.2 - 0.033 13.3 0.2 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative Phosphatase D123 PF07065.9 CBK25029.2 - 3.2e-11 42.8 1.3 5.4e-11 42.1 0.5 1.7 1 1 0 1 1 1 1 D123 Rsc14 PF08586.5 CBK25029.2 - 0.023 15.1 3.0 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF4439 PF14530.1 CBK25029.2 - 0.026 14.9 0.1 0.034 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Peptidase_C50 PF03568.12 CBK25029.2 - 0.056 12.1 1.1 0.063 11.9 0.8 1.2 1 0 0 1 1 1 0 Peptidase family C50 Rot1 PF10681.4 CBK25029.2 - 0.14 11.5 0.2 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Keratin_B2_2 PF13885.1 CBK25030.2 - 4.8e-06 26.1 20.5 0.03 14.0 7.1 4.3 1 1 1 2 2 2 2 Keratin, high sulfur B2 protein GRAM PF02893.15 CBK25030.2 - 0.0022 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 CBK25030.2 - 0.048 13.4 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 EF-hand_7 PF13499.1 CBK25031.2 - 7.5e-11 42.0 6.3 1.7e-09 37.6 1.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBK25031.2 - 2.9e-09 36.3 8.9 3.8e-08 32.8 0.7 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CBK25031.2 - 2.5e-08 33.7 0.3 8.1e-07 28.8 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBK25031.2 - 6.8e-08 31.2 7.3 2e-05 23.5 1.3 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBK25031.2 - 1.1e-07 31.1 5.0 0.031 14.1 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain DUF1456 PF07308.8 CBK25031.2 - 0.056 13.4 0.6 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_5 PF13202.1 CBK25031.2 - 0.071 12.4 0.9 0.071 12.4 0.6 3.5 4 0 0 4 4 4 0 EF hand RNase_H_2 PF13482.1 CBK25031.2 - 0.073 12.8 0.1 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily Vert_HS_TF PF06546.6 CBK25031.2 - 0.11 11.8 0.5 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Uteroglobin PF01099.12 CBK25031.2 - 0.12 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Uteroglobin family EF-hand_10 PF14788.1 CBK25031.2 - 0.2 11.3 4.5 0.23 11.1 0.8 2.5 2 1 1 3 3 3 0 EF hand DUF2121 PF09894.4 CBK25031.2 - 0.49 9.6 3.3 0.45 9.7 0.8 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) RNA_pol_Rpc34 PF05158.7 CBK25032.2 - 2.9e-42 145.0 2.1 3.2e-42 144.8 1.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 CBK25032.2 - 0.031 14.6 0.1 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal MarR_2 PF12802.2 CBK25032.2 - 0.044 13.4 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 MarR family Ribosomal_L39 PF00832.15 CBK25034.2 - 5.5e-18 64.1 8.6 5.8e-18 64.0 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Alpha-amylase PF00128.19 CBK25035.2 - 5.2e-14 52.3 0.0 9.1e-12 44.9 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 CBK25035.2 - 2.2e-09 37.3 0.1 5e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 CBK25036.2 - 5.5e-12 45.5 0.0 6.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SRP_SPB PF02978.14 CBK25037.2 - 2.7e-05 24.3 0.4 0.00034 20.8 0.0 2.3 2 1 0 2 2 2 1 Signal peptide binding domain DUF2153 PF09921.4 CBK25037.2 - 0.032 13.8 0.3 0.11 12.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) UPF0278 PF08745.6 CBK25037.2 - 0.051 12.8 0.1 0.095 11.9 0.1 1.5 1 1 0 1 1 1 0 UPF0278 family Sec1 PF00995.18 CBK25038.2 - 3.4e-16 58.9 0.0 4e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CBK25039.2 - 6.8e-47 160.3 0.1 8.1e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Sec1 family PX PF00787.19 CBK25040.2 - 1.2e-14 54.0 0.3 1.2e-14 54.0 0.2 2.5 3 0 0 3 3 3 1 PX domain Phasin_2 PF09361.5 CBK25040.2 - 0.057 13.4 3.7 1 9.4 1.4 3.1 3 0 0 3 3 3 0 Phasin protein TMPIT PF07851.8 CBK25040.2 - 0.061 12.3 0.2 0.061 12.3 0.1 3.1 3 0 0 3 3 3 0 TMPIT-like protein MCPsignal PF00015.16 CBK25040.2 - 1.9 7.9 13.2 0.052 13.0 1.7 2.8 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WD40 PF00400.27 CBK25041.2 - 4.6e-60 197.5 18.9 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK25041.2 - 5.5e-05 21.5 9.2 0.0062 14.7 0.1 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK25041.2 - 0.0019 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK25041.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK25041.2 - 0.007 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK25041.2 - 0.0096 14.8 0.2 0.44 9.4 0.1 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) Gmad1 PF10647.4 CBK25041.2 - 0.062 12.6 0.0 2.3 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK25041.2 - 0.082 13.2 0.2 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain SSXT PF05030.7 CBK25043.2 - 0.00014 21.3 0.1 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Glyco_transf_49 PF13896.1 CBK25044.2 - 1.1e-18 67.4 4.9 9e-15 54.5 1.5 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.1 CBK25045.2 - 1.9e-09 37.0 3.8 8e-08 31.7 0.5 2.5 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.8 CBK25045.2 - 0.00079 19.1 0.8 0.0027 17.4 0.3 2.0 1 1 1 2 2 2 2 F-box associated Ku_PK_bind PF08785.6 CBK25046.2 - 0.03 14.2 0.3 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 Ku C terminal domain like RNase_P_pop3 PF08228.6 CBK25046.2 - 0.097 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.21 CBK25047.2 - 2.8e-21 74.8 0.5 4.8e-21 74.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBK25047.2 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF563 PF04577.9 CBK25049.2 - 1.3e-20 74.1 1.0 2e-20 73.5 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Na_Ca_ex PF01699.19 CBK25052.2 - 3.6e-26 91.4 3.2 3.6e-26 91.4 2.2 2.2 2 0 0 2 2 2 1 Sodium/calcium exchanger protein YfhO PF09586.5 CBK25052.2 - 0.011 13.8 0.3 0.011 13.8 0.2 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Zip PF02535.17 CBK25053.2 - 8.3e-12 44.7 17.3 8.6e-10 38.1 3.4 2.8 2 1 1 3 3 3 2 ZIP Zinc transporter TcdA_TcdB_pore PF12920.2 CBK25053.2 - 0.051 11.4 0.1 0.067 11.0 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF2985 PF11204.3 CBK25053.2 - 0.11 12.2 2.7 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Ribosomal_S3Ae PF01015.13 CBK25054.2 - 1.8e-74 249.2 4.1 2.4e-74 248.9 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.17 CBK25054.2 - 0.00074 19.2 0.3 0.0025 17.5 0.1 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.11 CBK25054.2 - 0.041 13.2 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ist1 PF03398.9 CBK25055.2 - 1.8e-10 40.5 0.2 1.8e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway Nop14 PF04147.7 CBK25055.2 - 0.45 8.3 30.6 0.66 7.8 21.2 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 CBK25055.2 - 0.83 8.8 47.3 1.2 8.2 32.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 CBK25055.2 - 5.3 4.6 22.4 6.9 4.2 15.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SNF2_N PF00176.18 CBK25056.2 - 3.4e-56 190.2 0.0 4e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 CBK25056.2 - 4.3e-08 32.8 0.0 5.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBK25056.2 - 0.00039 20.2 0.0 0.0006 19.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 CBK25056.2 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 DEAD_2 Helicase_C PF00271.26 CBK25057.2 - 2.5e-09 36.8 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 CBK25058.2 - 6.9e-22 77.8 0.0 9.5e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25058.2 - 2.5e-14 52.9 0.0 3.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.1 CBK25059.2 - 4.7e-12 46.0 12.0 0.00055 20.2 1.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBK25059.2 - 1.1e-07 31.3 9.0 0.00078 19.0 0.2 4.7 5 1 0 5 5 5 2 TPR repeat TPR_16 PF13432.1 CBK25059.2 - 3e-07 30.9 7.4 0.023 15.3 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBK25059.2 - 1.1e-06 28.7 8.1 1.1 10.1 0.1 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBK25059.2 - 3.5e-05 23.3 12.3 0.0023 17.7 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CBK25059.2 - 0.00012 22.1 7.4 0.17 12.0 0.6 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBK25059.2 - 0.00053 19.8 0.3 0.00053 19.8 0.2 4.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25059.2 - 0.0038 17.2 4.1 0.057 13.6 0.1 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBK25059.2 - 0.0055 16.6 11.4 0.62 10.0 0.4 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat Linker_histone PF00538.14 CBK25059.2 - 0.017 15.2 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family TPR_20 PF14561.1 CBK25059.2 - 0.026 14.6 6.1 1.9 8.6 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBK25059.2 - 0.037 13.8 0.2 0.037 13.8 0.1 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBK25059.2 - 0.053 13.1 11.6 0.11 12.1 0.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Clathrin_H_link PF13838.1 CBK25059.2 - 0.061 13.2 0.2 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 Clathrin-H-link TPR_10 PF13374.1 CBK25059.2 - 1.9 8.5 9.7 1.4 8.9 0.5 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK25059.2 - 2.7 8.6 7.2 3.4 8.3 0.1 4.1 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBK25059.2 - 6.7 6.7 6.8 3 7.8 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat 6PF2K PF01591.13 CBK25060.2 - 5e-32 110.7 0.1 7.1e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CBK25060.2 - 6.3e-29 101.1 0.0 1.3e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HTH_WhiA PF02650.9 CBK25060.2 - 0.039 14.3 0.1 0.54 10.6 0.0 2.8 3 1 0 3 3 3 0 WhiA C-terminal HTH domain AAA_33 PF13671.1 CBK25060.2 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bacteroid_pep PF14406.1 CBK25061.2 - 0.055 13.6 0.3 0.055 13.6 0.2 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes PNP_UDP_1 PF01048.15 CBK25062.2 - 3.1e-33 114.7 0.0 4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily VIT1 PF01988.14 CBK25063.2 - 2.6 7.4 6.0 11 5.4 4.2 1.8 1 1 0 1 1 1 0 VIT family APC_CDC26 PF10471.4 CBK25063.2 - 4.3 8.1 9.4 4.2 8.1 5.6 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PHD PF00628.24 CBK25064.2 - 7.2e-07 28.8 15.4 7.2e-07 28.8 10.7 4.1 3 2 1 4 4 4 1 PHD-finger Epimerase PF01370.16 CBK25065.2 - 4.1e-40 137.6 0.0 5.5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBK25065.2 - 4.1e-22 77.8 0.7 6.4e-22 77.2 0.5 1.3 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CBK25065.2 - 1.1e-10 40.8 0.0 3.8e-09 35.8 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CBK25065.2 - 1.4e-10 40.3 0.0 1.4e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CBK25065.2 - 1.9e-08 33.5 0.0 6e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CBK25065.2 - 1e-05 24.6 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CBK25065.2 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CBK25065.2 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KAT11 PF08214.6 CBK25066.2 - 1.3e-35 123.0 0.0 5.2e-35 121.1 0.0 1.9 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.20 CBK25066.2 - 9.4e-22 76.7 0.0 2.7e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 CBK25066.2 - 0.007 16.0 7.2 0.007 16.0 5.0 3.6 4 0 0 4 4 4 1 PHD-finger Utp14 PF04615.8 CBK25068.2 - 2.9e-66 224.1 58.9 8e-47 159.8 24.5 2.6 2 1 0 2 2 2 2 Utp14 protein Rotamase PF00639.16 CBK25068.2 - 0.92 10.2 11.1 0.49 11.1 3.7 3.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Peptidase_M18 PF02127.10 CBK25069.2 - 2.8e-82 276.5 0.1 3.5e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBK25069.2 - 2.6e-05 23.1 0.0 4.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase He_PIG PF05345.7 CBK25070.2 - 3.2e-16 59.0 31.7 2.9e-06 27.1 7.1 4.9 4 1 0 4 4 4 3 Putative Ig domain Cadherin PF00028.12 CBK25070.2 - 0.025 14.8 0.9 0.077 13.2 0.0 2.2 2 1 0 2 2 2 0 Cadherin domain Baculo_11_kDa PF06143.6 CBK25070.2 - 0.086 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.1 CBK25070.2 - 0.096 13.0 0.5 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.8 CBK25070.2 - 0.11 12.9 0.3 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4020 PF13212.1 CBK25072.2 - 0.0002 21.0 4.3 0.0003 20.4 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4020) COX5A PF02284.11 CBK25072.2 - 0.0015 18.4 0.7 0.0031 17.4 0.5 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Va BAR PF03114.13 CBK25072.2 - 0.0027 17.2 3.1 0.0047 16.4 2.1 1.4 1 0 0 1 1 1 1 BAR domain YjcZ PF13990.1 CBK25072.2 - 0.0077 15.3 1.6 0.01 14.9 1.1 1.2 1 0 0 1 1 1 1 YjcZ-like protein Baculo_PEP_C PF04513.7 CBK25072.2 - 0.0098 15.7 1.8 0.022 14.6 1.3 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF217 PF02697.9 CBK25072.2 - 0.023 14.9 3.5 0.028 14.6 1.1 2.3 1 1 1 2 2 2 0 Uncharacterized ACR, COG1753 Polysacc_deac_2 PF04748.8 CBK25072.2 - 0.034 13.1 0.2 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Mitofilin PF09731.4 CBK25072.2 - 0.047 12.3 11.3 0.052 12.2 7.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF904 PF06005.7 CBK25072.2 - 0.09 13.0 10.2 18 5.7 7.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Phage_GPO PF05929.6 CBK25072.2 - 0.098 11.8 7.6 0.075 12.2 4.4 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Jnk-SapK_ap_N PF09744.4 CBK25072.2 - 0.11 12.5 11.8 0.081 12.9 7.4 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 CBK25072.2 - 0.11 12.4 7.9 0.33 10.9 1.9 2.8 3 1 0 3 3 2 0 bZIP transcription factor NumbF PF06311.7 CBK25072.2 - 0.13 12.4 2.2 8.8 6.5 1.5 2.5 1 1 0 1 1 1 0 NUMB domain IncA PF04156.9 CBK25072.2 - 0.14 11.7 7.4 0.17 11.4 5.1 1.2 1 0 0 1 1 1 0 IncA protein Rabaptin PF03528.10 CBK25072.2 - 0.45 10.4 14.1 1.4 8.8 0.4 2.4 1 1 0 2 2 2 0 Rabaptin Rootletin PF15035.1 CBK25072.2 - 0.8 9.6 10.4 1.2 9.1 7.2 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PIN_2 PF10130.4 CBK25072.2 - 0.88 9.6 4.3 0.31 11.0 0.6 1.9 2 1 1 3 3 3 0 PIN domain DUF641 PF04859.7 CBK25072.2 - 0.98 9.1 7.7 1.2 8.9 0.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 CBK25072.2 - 1 8.9 9.2 0.92 9.0 1.8 2.9 1 1 2 3 3 3 0 Septum formation initiator COG2 PF06148.6 CBK25072.2 - 1.7 8.4 7.3 4.2 7.2 5.1 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_2 PF07716.10 CBK25072.2 - 2.7 7.9 10.4 1.3 8.8 2.7 2.9 3 0 0 3 3 3 0 Basic region leucine zipper APG6 PF04111.7 CBK25072.2 - 3.3 6.6 15.0 0.81 8.6 6.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 CBK25072.2 - 4 7.5 13.6 0.74 9.9 4.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LSM14 PF12701.2 CBK25074.2 - 2.5e-20 72.0 0.4 4.3e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain LamB_YcsF PF03746.11 CBK25074.2 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 LamB/YcsF family FDF PF09532.5 CBK25074.2 - 6.3 7.3 11.4 11 6.6 2.5 2.7 1 1 1 2 2 2 0 FDF domain ABC_membrane PF00664.18 CBK25075.2 - 3e-64 217.0 38.1 2.3e-36 125.6 10.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBK25075.2 - 2.1e-53 180.2 0.7 3.5e-30 105.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CBK25075.2 - 1.4e-09 37.5 11.6 0.0029 16.8 0.1 4.4 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBK25075.2 - 2.2e-08 34.4 0.3 0.16 11.8 0.0 4.5 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBK25075.2 - 1.2e-06 27.8 0.1 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBK25075.2 - 3.4e-06 26.9 1.0 0.022 14.7 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBK25075.2 - 9.3e-06 25.5 3.0 0.013 15.3 0.0 3.5 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.1 CBK25075.2 - 1e-05 25.6 1.4 0.12 12.3 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain Sec62 PF03839.11 CBK25075.2 - 7.9e-05 22.1 0.7 7.9e-05 22.1 0.5 1.7 2 0 0 2 2 1 1 Translocation protein Sec62 AAA_29 PF13555.1 CBK25075.2 - 0.00013 21.3 0.2 0.26 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CBK25075.2 - 0.00039 19.8 0.0 0.054 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBK25075.2 - 0.00058 20.2 11.6 0.0061 16.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CBK25075.2 - 0.0042 16.0 0.2 1.3 7.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Miro PF08477.8 CBK25075.2 - 0.0085 16.5 9.9 0.62 10.5 0.0 3.9 5 0 0 5 5 3 2 Miro-like protein Zeta_toxin PF06414.7 CBK25075.2 - 0.013 14.6 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 CBK25075.2 - 0.025 14.4 3.6 0.43 10.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CBK25075.2 - 0.027 13.9 0.2 6.1 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 CBK25075.2 - 0.039 13.0 0.0 0.039 13.0 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 CBK25075.2 - 0.044 13.9 0.1 8.8 6.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CBK25075.2 - 0.078 12.3 1.7 0.89 8.9 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CBK25075.2 - 0.1 13.4 0.4 26 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain CDC50 PF03381.10 CBK25075.2 - 0.19 10.8 0.4 6.9 5.7 0.2 3.1 3 0 0 3 3 3 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Orthoreo_P10 PF07204.6 CBK25075.2 - 9.3 6.0 12.4 1.6 8.5 1.6 3.3 3 1 0 3 3 2 0 Orthoreovirus membrane fusion protein p10 WHIM1 PF15612.1 CBK25076.2 - 0.08 12.9 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 VirB3 PF05101.8 CBK25077.2 - 0.0076 16.2 2.5 0.0076 16.2 1.8 2.2 2 1 1 3 3 3 1 Type IV secretory pathway, VirB3-like protein DUF202 PF02656.10 CBK25077.2 - 0.31 11.2 0.0 0.31 11.2 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Na_Ala_symp PF01235.12 CBK25077.2 - 0.9 8.0 14.4 0.03 12.8 4.6 2.0 1 1 1 2 2 2 0 Sodium:alanine symporter family DUF373 PF04123.8 CBK25077.2 - 1.6 7.6 11.3 2.4 7.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Neurensin PF14927.1 CBK25077.2 - 3.3 7.1 6.2 2.1e+02 1.2 4.2 2.6 1 1 0 1 1 1 0 Neurensin Viral_Beta_CD PF04530.7 CBK25077.2 - 6.8 6.8 9.3 12 6.0 0.0 2.8 2 1 1 3 3 3 0 Viral Beta C/D like family PA28_beta PF02252.13 CBK25078.2 - 7e-34 116.4 0.0 8.4e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit HSP70 PF00012.15 CBK25079.2 - 3.9e-63 213.3 0.1 2.7e-62 210.5 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK25079.2 - 2.2e-11 42.9 0.0 4.4e-05 22.2 0.0 3.3 3 1 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.1 CBK25079.2 - 1.1e-05 25.2 0.4 0.0085 15.9 0.0 3.5 3 0 0 3 3 3 1 Cell division protein FtsA StbA PF06406.6 CBK25079.2 - 0.00032 19.7 0.0 0.021 13.7 0.0 2.3 1 1 1 2 2 2 1 StbA protein DDR PF08841.5 CBK25079.2 - 0.00099 18.0 0.0 0.13 11.0 0.0 2.5 2 1 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain CP_ATPgrasp_1 PF04174.8 CBK25079.2 - 0.1 11.1 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp HSP70 PF00012.15 CBK25080.2 - 4.2e-62 209.9 0.0 5.7e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK25080.2 - 5.8e-09 34.9 0.0 2.5e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 CBK25080.2 - 0.0001 22.1 0.5 0.085 12.6 0.0 3.8 4 0 0 4 4 4 1 Cell division protein FtsA StbA PF06406.6 CBK25080.2 - 0.0023 16.9 0.0 0.79 8.5 0.0 2.2 1 1 1 2 2 2 2 StbA protein DDR PF08841.5 CBK25080.2 - 0.1 11.3 0.0 0.69 8.6 0.0 2.2 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain DUF2215 PF10225.4 CBK25081.2 - 1.3e-13 51.0 10.1 1.6e-13 50.7 7.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) DUF4105 PF13387.1 CBK25081.2 - 0.17 11.0 2.0 0.28 10.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Coa1 PF08695.5 CBK25082.2 - 2.7e-09 36.5 0.0 3.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 He_PIG PF05345.7 CBK25083.2 - 1.1e-16 60.5 15.8 1.5e-05 24.8 1.4 5.8 5 0 0 5 5 5 3 Putative Ig domain ASFV_J13L PF05568.6 CBK25083.2 - 0.01 15.3 1.0 0.027 14.0 0.7 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein ODV-E18 PF10717.4 CBK25083.2 - 0.021 14.2 0.1 0.073 12.5 0.1 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Soyouz_module PF14313.1 CBK25083.2 - 0.063 12.8 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) P12 PF12669.2 CBK25083.2 - 5.8 7.1 4.9 11 6.3 3.4 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Aldo_ket_red PF00248.16 CBK25085.2 - 7.6e-60 202.1 0.0 9.4e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 CBK25086.2 - 2.9e-64 216.7 0.1 6.6e-64 215.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25086.2 - 7.6e-38 130.0 0.0 1.2e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK25086.2 - 5.9e-07 28.7 0.0 1.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBK25086.2 - 4.4e-05 22.6 1.0 6.6e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK25086.2 - 0.00013 21.4 0.3 0.00025 20.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 CBK25086.2 - 0.00051 18.9 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CBK25086.2 - 0.0065 16.2 0.0 0.023 14.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Nse4_C PF08743.5 CBK25087.2 - 9.5e-11 41.5 0.0 2.2e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Nse4 C-terminal EIIBC-GUT_N PF03612.9 CBK25087.2 - 0.095 12.3 0.6 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus A1_Propeptide PF07966.7 CBK25087.2 - 0.46 10.3 0.2 0.46 10.3 0.1 2.5 3 0 0 3 3 3 0 A1 Propeptide Pkinase PF00069.20 CBK25088.2 - 5.7e-09 35.4 0.5 7.8e-09 35.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain DDE_Tnp_ISL3 PF01610.12 CBK25088.2 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Transposase Pkinase_Tyr PF07714.12 CBK25088.2 - 0.0055 15.8 1.9 0.017 14.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Rtt102p PF09510.5 CBK25088.2 - 0.014 15.3 0.3 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein PFK PF00365.15 CBK25089.2 - 8.5e-26 90.5 0.2 1.5e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Phosphofructokinase DUF2186 PF09952.4 CBK25089.2 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) Na_H_antiporter PF03553.9 CBK25090.2 - 9.7e-45 152.8 14.7 9.7e-45 152.8 10.2 2.3 1 1 1 2 2 2 1 Na+/H+ antiporter family FixP_N PF14715.1 CBK25090.2 - 0.036 13.4 0.1 0.036 13.4 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1840 PF08895.6 CBK25090.2 - 0.21 11.6 1.1 0.34 10.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) G-patch PF01585.18 CBK25091.2 - 1.3e-11 44.0 2.7 2.8e-11 42.9 1.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBK25091.2 - 9.3e-06 25.4 0.6 9.3e-06 25.4 0.4 1.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site DEAD PF00270.24 CBK25092.2 - 6.5e-17 61.5 0.0 2.3e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBK25092.2 - 3.3e-09 36.4 0.0 9.4e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBK25092.2 - 0.0028 16.7 0.7 0.012 14.6 0.0 2.2 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 CBK25092.2 - 0.0029 16.0 0.0 0.0076 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Exo_endo_phos PF03372.18 CBK25093.2 - 3.2e-14 53.4 1.2 5.2e-14 52.7 0.8 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1632 PF07857.7 CBK25094.2 - 2.8e-58 197.1 10.3 2.8e-58 197.1 7.2 1.8 2 0 0 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 CBK25094.2 - 6.5e-10 38.5 16.0 8.2e-08 31.6 1.5 2.3 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.6 CBK25094.2 - 0.0014 17.4 0.8 0.0029 16.3 0.5 1.6 1 1 0 1 1 1 1 Ureide permease Ribosomal_S8e PF01201.17 CBK25095.2 - 6.5e-35 120.1 0.1 7.7e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_5 PF14634.1 CBK25096.2 - 3e-08 33.2 10.4 5e-08 32.5 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBK25096.2 - 0.0029 17.5 12.0 0.005 16.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBK25096.2 - 0.0035 16.9 10.9 0.0054 16.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 CBK25096.2 - 0.01 15.0 4.3 0.01 15.0 3.0 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_2 PF13639.1 CBK25096.2 - 0.012 15.4 10.5 0.02 14.7 7.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CBK25096.2 - 0.018 14.6 11.2 0.036 13.7 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 CBK25096.2 - 0.11 12.3 7.9 0.25 11.1 5.5 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 CBK25096.2 - 0.96 9.0 6.5 1.7 8.2 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.2 CBK25096.2 - 1.3 8.9 7.3 6.8 6.5 0.9 2.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain ATP-grasp_5 PF13549.1 CBK25099.2 - 1.4e-79 266.3 0.9 2e-79 265.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CBK25099.2 - 6.4e-57 191.0 0.6 1.9e-56 189.5 0.4 1.9 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK25099.2 - 8.2e-24 84.0 3.3 7.9e-23 80.8 0.1 3.5 4 0 0 4 4 4 1 CoA binding domain CoA_binding PF02629.14 CBK25099.2 - 2.3e-15 56.8 0.7 9.4e-15 54.9 0.1 2.5 2 0 0 2 2 1 1 CoA binding domain Acetyltransf_1 PF00583.19 CBK25099.2 - 3.8e-07 30.0 0.1 9e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ATP-grasp_4 PF13535.1 CBK25099.2 - 9.8e-06 25.4 0.2 0.0012 18.6 0.0 3.8 4 1 1 5 5 5 1 ATP-grasp domain Acetyltransf_3 PF13302.1 CBK25099.2 - 3.4e-05 24.0 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBK25099.2 - 3.5e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBK25099.2 - 4.6e-05 23.2 1.5 0.0014 18.4 0.1 3.2 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase ATP-grasp_2 PF08442.5 CBK25099.2 - 9.6e-05 21.8 0.1 0.00027 20.3 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_10 PF13673.1 CBK25099.2 - 0.00042 20.4 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBK25099.2 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.12 CBK25099.2 - 0.0069 15.6 0.2 0.028 13.7 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CBK25099.2 - 0.024 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DENN PF02141.16 CBK25101.2 - 5.6e-33 114.2 2.3 1.1e-32 113.2 1.6 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 CBK25101.2 - 1.7e-12 47.1 0.2 5.1e-12 45.6 0.2 1.8 2 0 0 2 2 2 1 dDENN domain PDZ PF00595.19 CBK25101.2 - 0.0048 17.0 0.1 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) SPA PF08616.5 CBK25101.2 - 0.061 13.0 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis CN_hydrolase PF00795.17 CBK25102.2 - 3.9e-34 117.6 0.0 5.5e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MIF4G PF02854.14 CBK25104.2 - 4.4e-05 22.9 0.1 0.0001 21.7 0.1 1.5 1 1 0 1 1 1 1 MIF4G domain Ribosomal_L18ae PF01775.12 CBK25105.2 - 1.1e-52 177.1 0.2 1.6e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Ribosomal_L32e PF01655.13 CBK25106.2 - 2.7e-46 156.1 0.3 3.4e-46 155.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CutC PF03932.9 CBK25107.2 - 5.7e-77 257.5 2.7 6.8e-77 257.3 1.9 1.1 1 0 0 1 1 1 1 CutC family DeoC PF01791.4 CBK25107.2 - 2.2e-05 23.9 0.1 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 DeoC/LacD family aldolase QRPTase_C PF01729.14 CBK25107.2 - 0.01 15.3 0.1 0.033 13.7 0.0 1.8 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.12 CBK25107.2 - 0.048 12.7 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI BtpA PF03437.10 CBK25107.2 - 0.05 12.8 2.7 0.54 9.4 1.9 2.3 1 1 0 1 1 1 0 BtpA family DGF-1_5 PF11038.3 CBK25107.2 - 0.16 11.1 0.6 0.55 9.3 0.1 1.8 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Complex1_51K PF01512.12 CBK25108.2 - 4.9e-43 146.4 0.0 7.8e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CBK25108.2 - 1.9e-18 65.2 0.8 4.3e-18 64.2 0.5 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CBK25108.2 - 2.1e-07 30.6 0.0 5.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain ACT PF01842.20 CBK25109.2 - 0.29 10.6 1.5 0.28 10.7 0.2 1.6 2 0 0 2 2 2 0 ACT domain MMR_HSR1 PF01926.18 CBK25110.2 - 2e-20 72.8 0.2 1.5e-15 57.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK25110.2 - 8.7e-08 31.5 0.3 1.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBK25110.2 - 5.4e-06 25.9 3.0 0.002 17.5 0.0 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CBK25110.2 - 2e-05 25.0 0.7 0.068 13.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 CBK25110.2 - 0.00014 21.1 0.3 0.49 9.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CBK25110.2 - 0.00049 19.3 0.1 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBK25110.2 - 0.00051 19.8 9.9 0.011 15.6 0.2 3.4 2 2 1 3 3 3 1 Dynamin family Gtr1_RagA PF04670.7 CBK25110.2 - 0.009 15.1 0.8 0.083 12.0 0.1 2.3 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 CBK25110.2 - 0.03 14.6 0.2 0.25 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain Ras PF00071.17 CBK25110.2 - 0.078 12.3 1.5 1.6 8.0 0.0 2.8 2 1 1 3 3 3 0 Ras family AAA_16 PF13191.1 CBK25110.2 - 0.21 11.5 1.9 3.4 7.6 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain Clathrin_lg_ch PF01086.12 CBK25111.2 - 4.8e-16 59.3 6.1 5.7e-16 59.1 4.2 1.1 1 0 0 1 1 1 1 Clathrin light chain NUFIP1 PF10453.4 CBK25111.2 - 0.15 11.5 6.3 0.26 10.7 4.4 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) tRNA-synt_1_2 PF13603.1 CBK25111.2 - 0.17 11.1 1.0 1 8.6 0.1 2.0 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 FAM60A PF15396.1 CBK25111.2 - 3 7.5 6.3 3.5 7.2 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A WD40 PF00400.27 CBK25112.2 - 4.5e-60 197.5 18.6 5.5e-12 45.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBK25112.2 - 4.3e-05 21.8 8.9 0.0062 14.7 0.1 4.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.6 CBK25112.2 - 0.002 17.4 2.9 0.46 9.6 0.0 3.4 2 2 1 3 3 3 2 TUP1-like enhancer of split PQQ_2 PF13360.1 CBK25112.2 - 0.0037 16.7 1.5 0.086 12.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBK25112.2 - 0.0071 14.6 0.0 0.33 9.2 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 CBK25112.2 - 0.011 14.6 0.2 0.45 9.3 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Gmad1 PF10647.4 CBK25112.2 - 0.067 12.5 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBK25112.2 - 0.068 13.4 0.1 49 4.3 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain DUF4573 PF15140.1 CBK25113.2 - 0.00031 20.4 22.3 0.00052 19.6 15.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) ECM11 PF15463.1 CBK25113.2 - 9.7 6.4 9.4 0.4 10.9 0.8 2.1 1 1 1 2 2 2 0 Extracellular mutant protein 11 MIP-T3 PF10243.4 CBK25114.2 - 0.021 13.3 54.3 0.025 13.0 37.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SecE PF00584.15 CBK25114.2 - 0.057 13.0 0.9 0.1 12.1 0.7 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex LMBR1 PF04791.11 CBK25114.2 - 1.7 7.1 10.0 3.7 6.0 5.9 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Macoilin PF09726.4 CBK25114.2 - 3.2 5.9 19.2 4 5.6 13.3 1.1 1 0 0 1 1 1 0 Transmembrane protein POR_N PF01855.14 CBK25115.2 - 6.5e-72 241.7 0.5 2.6e-71 239.8 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.15 CBK25115.2 - 7.2e-43 146.5 0.0 1.2e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBK25115.2 - 2.8e-25 88.9 0.1 7e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 Flavodoxin EKR PF10371.4 CBK25115.2 - 5.1e-21 73.9 0.2 4.4e-20 71.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function POR PF01558.13 CBK25115.2 - 4.7e-20 72.1 0.0 1.5e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.16 CBK25115.2 - 1.6e-08 35.0 0.0 6.5e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.1 CBK25115.2 - 3.5e-08 33.5 10.5 0.0011 19.1 1.3 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBK25115.2 - 1e-07 32.1 9.9 1e-07 32.1 6.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK25115.2 - 1.7e-07 31.8 8.9 0.0036 18.0 1.2 3.0 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.16 CBK25115.2 - 2.2e-07 30.5 0.1 5.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.22 CBK25115.2 - 1.6e-06 27.4 23.8 0.00015 21.1 3.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.1 CBK25115.2 - 2.4e-06 27.2 8.8 2.4e-06 27.2 6.1 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.15 CBK25115.2 - 8.1e-06 25.7 0.2 2.9e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 Transketolase, C-terminal domain Fer4_8 PF13183.1 CBK25115.2 - 1.1e-05 25.4 7.9 3.7e-05 23.6 5.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 CBK25115.2 - 4.3e-05 23.7 7.1 0.017 15.4 1.5 3.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CBK25115.2 - 9.6e-05 22.1 14.2 0.001 18.9 9.9 2.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 CBK25115.2 - 0.00025 20.7 7.0 0.00025 20.7 4.8 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.1 CBK25115.2 - 0.00034 20.9 5.9 0.086 13.2 0.2 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CBK25115.2 - 0.00044 19.9 18.1 0.0013 18.5 1.7 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Flavodoxin_5 PF12724.2 CBK25115.2 - 0.082 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain GSH-S_N PF02951.9 CBK25115.2 - 0.087 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Fer4_15 PF13459.1 CBK25115.2 - 2 9.0 11.5 3.4 8.3 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain PseudoU_synth_1 PF01416.15 CBK25116.2 - 3.7e-12 46.5 0.0 7.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase GTP_EFTU PF00009.22 CBK25117.2 - 1.7e-56 190.6 0.0 2.3e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK25117.2 - 1e-33 115.4 0.1 3.1e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK25117.2 - 5.6e-10 39.1 0.1 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK25117.2 - 0.00011 22.1 0.1 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBK25117.2 - 0.029 13.5 0.4 0.072 12.2 0.1 1.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK25117.2 - 0.04 14.4 0.4 0.61 10.5 0.3 2.4 1 1 0 1 1 1 0 Miro-like protein Glyco_hydro_35 PF01301.14 CBK25118.2 - 1.7e-112 375.9 1.3 2.1e-112 375.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CBK25118.2 - 3.5e-14 52.7 0.1 1.4e-12 47.4 0.1 2.3 1 1 0 1 1 1 1 Beta-galactosidase WD40 PF00400.27 CBK25119.2 - 3.6e-35 118.5 6.4 2.6e-08 33.4 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 CBK25119.2 - 2.1e-05 24.3 0.0 0.058 13.0 0.0 3.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 CBK25119.2 - 0.0014 18.6 2.2 24 5.2 0.0 5.5 6 0 0 6 6 6 1 Kelch motif TFIIIC_delta PF12657.2 CBK25119.2 - 0.0078 15.9 0.3 3.9 7.1 0.0 3.2 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term WW PF00397.21 CBK25120.2 - 5.6e-07 29.3 0.6 1.1e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 WW domain zf-RanBP PF00641.13 CBK25120.2 - 9.6e-06 24.5 3.6 2.4e-05 23.3 2.5 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CBK25120.2 - 0.00041 19.9 0.1 0.0011 18.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK25120.2 - 0.0074 16.1 0.6 0.026 14.3 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK25120.2 - 0.014 15.3 0.3 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK25120.2 - 0.079 12.7 0.2 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-ribbon_3 PF13248.1 CBK25120.2 - 0.63 9.3 5.1 1.2 8.4 3.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Kinesin PF00225.18 CBK25121.2 - 1.8e-66 224.1 0.5 2.2e-66 223.8 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 CBK25122.2 - 9.7e-05 22.0 6.0 0.00016 21.4 4.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CBK25122.2 - 0.00062 20.0 2.5 0.0011 19.3 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) ADIP PF11559.3 CBK25122.2 - 0.0018 18.1 9.5 0.0027 17.6 6.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Effector_1 PF04518.7 CBK25122.2 - 0.0068 15.4 0.4 0.0068 15.4 0.2 1.9 1 1 1 2 2 2 1 Effector from type III secretion system GAS PF13851.1 CBK25122.2 - 0.021 14.0 4.6 0.032 13.4 3.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBK25122.2 - 0.024 13.7 5.9 0.031 13.3 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin-relat_1 PF12711.2 CBK25122.2 - 0.029 14.7 3.0 0.036 14.4 0.7 2.1 1 1 1 2 2 2 0 Kinesin motor ERM PF00769.14 CBK25122.2 - 0.04 13.4 10.4 0.056 12.9 7.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 CBK25122.2 - 0.069 11.6 3.3 0.092 11.1 2.3 1.1 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 CBK25122.2 - 0.092 11.0 5.6 0.12 10.6 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 CBK25122.2 - 0.15 9.4 7.9 0.19 8.9 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Borrelia_REV PF03978.8 CBK25122.2 - 0.22 11.2 0.7 0.33 10.6 0.5 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein HlyD PF00529.15 CBK25122.2 - 0.23 10.7 11.6 0.38 9.9 8.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein OmpH PF03938.9 CBK25122.2 - 0.47 10.3 10.6 0.71 9.8 7.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rab5-bind PF09311.6 CBK25122.2 - 0.53 10.1 13.6 0.53 10.1 8.6 1.5 1 1 1 2 2 2 0 Rabaptin-like protein TBPIP PF07106.8 CBK25122.2 - 0.59 9.6 4.4 0.87 9.1 3.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 CBK25122.2 - 0.62 10.2 4.5 1.1 9.4 3.1 1.4 1 0 0 1 1 1 0 Syntaxin Rep_4 PF05797.6 CBK25122.2 - 0.68 8.5 3.0 0.92 8.1 2.1 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF4407 PF14362.1 CBK25122.2 - 0.77 8.6 10.6 1.1 8.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.4 CBK25122.2 - 1.3 8.8 9.1 11 5.8 6.3 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 CBK25122.2 - 2.3 8.1 4.7 3 7.7 0.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GP20 PF06810.6 CBK25122.2 - 2.3 7.6 8.9 4.1 6.8 6.2 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF111 PF01969.12 CBK25122.2 - 9 4.9 6.8 2 7.1 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF111 Atg14 PF10186.4 CBK25122.2 - 9 5.1 9.4 21 3.9 6.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Alg6_Alg8 PF03155.10 CBK25123.2 - 2.2e-89 300.4 20.4 2.9e-89 300.0 14.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family CTP_transf_1 PF01148.15 CBK25124.2 - 7.8e-06 25.7 4.2 7.8e-06 25.7 2.9 1.3 2 0 0 2 2 2 1 Cytidylyltransferase family Cytochrom_B561 PF03188.11 CBK25124.2 - 0.23 11.3 2.7 0.51 10.1 1.6 1.9 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF3816 PF12822.2 CBK25124.2 - 0.28 11.0 6.9 0.34 10.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF4064 PF13273.1 CBK25124.2 - 4.7 7.3 8.6 2.5 8.2 2.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Glyco_trans_1_4 PF13692.1 CBK25125.2 - 6.2e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBK25125.2 - 6.9e-12 45.1 0.0 3.8e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBK25125.2 - 2.6e-07 30.8 0.0 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CBK25125.2 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CBK25125.2 - 0.00071 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Fe_hyd_lg_C PF02906.9 CBK25126.2 - 4.6e-107 357.5 0.4 8.4e-107 356.6 0.2 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Flavodoxin_1 PF00258.20 CBK25126.2 - 2.9e-33 114.8 0.5 6.7e-33 113.6 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin Fe_hyd_SSU PF02256.12 CBK25126.2 - 4.8e-25 87.3 0.3 1.1e-24 86.2 0.2 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.1 CBK25126.2 - 6.8e-18 64.2 0.3 2.2e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBK25126.2 - 1.4e-08 34.3 0.4 1.4e-08 34.3 0.3 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CBK25126.2 - 5e-07 29.8 7.6 1.8e-06 28.0 3.6 3.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBK25126.2 - 6.6e-07 29.0 6.5 0.0031 17.2 0.2 3.4 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CBK25126.2 - 3.1e-06 27.8 10.2 0.003 18.2 0.3 4.1 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CBK25126.2 - 7.8e-06 25.6 7.7 3.3e-05 23.6 5.3 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK25126.2 - 1.6e-05 25.2 9.2 0.0051 17.1 0.8 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 CBK25126.2 - 2.6e-05 23.6 24.3 0.00022 20.6 2.1 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_7 PF12838.2 CBK25126.2 - 3.9e-05 23.9 19.6 0.00015 22.1 6.8 3.9 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 CBK25126.2 - 4.2e-05 24.0 7.6 0.073 13.6 0.2 4.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_17 PF13534.1 CBK25126.2 - 4.7e-05 23.6 9.1 0.12 12.7 0.2 3.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBK25126.2 - 0.00012 22.0 7.6 0.00012 22.0 5.3 2.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Flavodoxin_5 PF12724.2 CBK25126.2 - 0.00022 21.2 0.0 0.00069 19.6 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 CBK25126.2 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 NrdI Flavodoxin like Fer4_6 PF12837.2 CBK25126.2 - 0.0016 18.1 1.3 0.0016 18.1 0.9 3.4 4 0 0 4 4 3 2 4Fe-4S binding domain Flavodoxin_3 PF12641.2 CBK25126.2 - 0.037 13.4 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain HPS3_C PF14763.1 CBK25126.2 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal Fer4_13 PF13370.1 CBK25126.2 - 0.13 12.6 11.3 1.2 9.5 2.0 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 CBK25126.2 - 0.3 11.5 20.0 0.064 13.6 1.4 4.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.2 CBK25126.2 - 0.45 10.5 23.8 0.068 13.1 0.9 3.8 4 0 0 4 4 3 0 4Fe-4S binding domain WD40 PF00400.27 CBK25128.2 - 2.8e-62 204.5 19.9 8e-10 38.2 0.1 9.7 9 1 0 9 9 9 8 WD domain, G-beta repeat Nup160 PF11715.3 CBK25128.2 - 2.1e-09 36.0 12.8 0.1 10.7 0.1 7.0 3 2 4 7 7 7 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK25128.2 - 1.7e-05 23.7 3.5 0.037 12.7 0.0 4.9 2 2 0 2 2 2 2 Nup133 N terminal like Flavokinase PF01687.12 CBK25129.2 - 3.4e-38 130.3 0.0 4.1e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase DUF3201 PF11447.3 CBK25129.2 - 0.073 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) tRNA-synt_1c PF00749.16 CBK25131.2 - 4.1e-103 344.3 0.0 6e-103 343.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBK25131.2 - 3e-40 137.7 0.0 5.4e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 CBK25131.2 - 1.8e-21 76.3 0.3 3.7e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 CBK25131.2 - 3.6e-06 27.5 5.0 1.6e-05 25.5 3.5 2.1 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FliL PF03748.9 CBK25131.2 - 0.063 13.2 0.2 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF1032 PF06278.6 CBK25132.2 - 6.1e-17 61.3 0.1 7e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1032) Rad21_Rec8_N PF04825.8 CBK25132.2 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein DUF1032 PF06278.6 CBK25133.2 - 2.8e-21 75.6 0.1 3.3e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1032) ScpA_ScpB PF02616.9 CBK25133.2 - 0.0005 19.7 1.2 0.00056 19.5 0.9 1.1 1 0 0 1 1 1 1 ScpA/B protein MRP-L20 PF12824.2 CBK25133.2 - 0.027 14.4 0.2 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 FdhE PF04216.7 CBK25133.2 - 0.074 12.7 0.1 0.086 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation CobD_Cbib PF03186.8 CBK25134.2 - 0.067 12.2 0.6 0.084 11.9 0.4 1.1 1 0 0 1 1 1 0 CobD/Cbib protein DPM3 PF08285.6 CBK25134.2 - 2.6 7.9 5.6 0.86 9.4 0.4 2.2 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GBP PF02263.14 CBK25135.2 - 4e-33 114.5 0.0 5.4e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain He_PIG PF05345.7 CBK25136.2 - 1.1e-13 50.9 10.8 4.8e-05 23.3 0.8 5.0 3 0 0 3 3 3 3 Putative Ig domain Sushi PF00084.15 CBK25136.2 - 0.33 11.3 5.5 0.18 12.1 0.3 3.0 2 0 0 2 2 2 0 Sushi domain (SCR repeat) Ribosomal_L10 PF00466.15 CBK25137.2 - 1.9e-19 69.4 0.0 2.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 F-actin_cap_A PF01267.12 CBK25137.2 - 0.0022 17.0 0.2 0.0043 16.1 0.1 1.4 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Histone PF00125.19 CBK25138.2 - 1.9e-17 63.1 0.1 2.5e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK25138.2 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBK25138.2 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 CBK25139.2 - 2.9e-23 81.7 0.1 4.3e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBK25139.2 - 3.8e-05 23.6 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFX_C PF14601.1 CBK25139.2 - 0.038 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term GSHPx PF00255.14 CBK25140.2 - 5.9e-42 141.4 0.1 7.2e-42 141.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CBK25140.2 - 3.6e-06 26.6 0.0 4.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK25140.2 - 0.00016 21.2 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin CPSase_L_D2 PF02786.12 CBK25141.2 - 8.9e-108 358.4 0.0 2.6e-80 268.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CBK25141.2 - 6.7e-51 171.2 0.0 1.2e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CBK25141.2 - 1.8e-46 157.9 0.0 3.8e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 CBK25141.2 - 4.3e-38 129.7 0.0 7.9e-18 64.5 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CBK25141.2 - 8.5e-37 125.6 0.1 3.4e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CBK25141.2 - 7.8e-29 100.7 0.1 4.4e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBK25141.2 - 6.7e-15 54.6 0.0 9.2e-08 31.1 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CBK25141.2 - 1.3e-14 53.8 0.0 2.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 CBK25141.2 - 7.4e-14 51.4 0.0 4.9e-13 48.8 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CBK25141.2 - 1.3e-13 50.8 0.1 9.6e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CBK25141.2 - 6.2e-08 32.3 0.0 0.00018 21.0 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBK25141.2 - 3.7e-07 30.1 0.1 0.0083 15.9 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CBK25141.2 - 4.8e-05 22.9 0.1 0.00081 18.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_5 PF13549.1 CBK25141.2 - 0.016 14.4 0.0 3.2 6.9 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.14 CBK25141.2 - 0.06 12.8 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Fe-ADH PF00465.14 CBK25142.2 - 4.9e-70 236.0 0.0 5.9e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK25142.2 - 1.7e-08 34.1 0.0 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CbiK PF06180.6 CBK25142.2 - 0.018 14.1 0.0 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) UPF0139 PF03669.8 CBK25143.2 - 5.6e-07 29.0 0.2 5.9e-07 28.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF3955 PF13127.1 CBK25143.2 - 8.8 5.9 8.1 5.3 6.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3955) HGTP_anticodon PF03129.15 CBK25144.2 - 1.2e-18 66.8 0.1 5.2e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HSP70 PF00012.15 CBK25145.2 - 5.9e-14 50.9 0.0 8.1e-14 50.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein CoA_binding PF02629.14 CBK25145.2 - 0.092 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Fe-ADH PF00465.14 CBK25146.2 - 3.6e-70 236.4 0.0 4.3e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBK25146.2 - 3.2e-09 36.4 0.1 4.3e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CbiK PF06180.6 CBK25146.2 - 0.02 13.9 0.0 0.052 12.6 0.0 1.6 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) DHQ_synthase PF01761.15 CBK25146.2 - 0.039 12.8 0.1 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 3-dehydroquinate synthase Ribosomal_L4 PF00573.17 CBK25149.2 - 3e-43 147.4 0.2 5.3e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBK25149.2 - 9.6e-22 76.6 4.4 1.1e-21 76.4 2.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L2_C PF03947.13 CBK25150.2 - 2e-41 140.8 0.7 2.7e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBK25150.2 - 2.2e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mtc PF03820.12 CBK25151.2 - 1.2e-85 286.9 0.0 1.3e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ribosomal_S19 PF00203.16 CBK25152.2 - 5.1e-32 109.3 0.2 6.3e-32 109.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Vps53_N PF04100.7 CBK25153.2 - 5.1e-70 236.1 11.7 2.6e-69 233.8 8.1 1.9 1 1 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 CBK25153.2 - 1.6e-05 23.2 0.2 1.6e-05 23.2 0.1 3.3 2 1 2 4 4 4 2 Exocyst complex component Sec6 DUF2450 PF10475.4 CBK25153.2 - 0.00062 18.7 6.2 0.0015 17.4 3.9 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Laminin_II PF06009.7 CBK25153.2 - 0.0017 18.1 4.8 0.0031 17.2 2.8 1.9 1 1 0 1 1 1 1 Laminin Domain II Sec5 PF15469.1 CBK25153.2 - 0.074 12.7 3.7 0.16 11.7 2.5 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 Laminin_I PF06008.9 CBK25153.2 - 0.27 10.4 10.1 0.058 12.6 4.2 2.0 2 0 0 2 2 2 0 Laminin Domain I Spc7 PF08317.6 CBK25153.2 - 0.32 9.6 7.9 0.6 8.7 5.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ING PF12998.2 CBK25153.2 - 0.5 10.6 7.8 0.47 10.7 4.1 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.7 CBK25153.2 - 2.9 7.7 6.9 7.7 6.3 3.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBK25153.2 - 9.6 5.7 15.0 0.15 11.6 4.7 2.3 3 0 0 3 3 3 0 IncA protein HSP70 PF00012.15 CBK25154.2 - 3.5e-52 177.1 0.0 4.1e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK25154.2 - 6e-17 61.2 0.0 2.1e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBK25154.2 - 0.0004 19.4 0.0 0.00078 18.4 0.0 1.4 1 0 0 1 1 1 1 StbA protein Hydantoinase_A PF01968.13 CBK25154.2 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PilM_2 PF11104.3 CBK25154.2 - 0.028 13.3 0.1 0.07 12.0 0.0 1.7 1 1 0 1 1 1 0 Type IV pilus assembly protein PilM; FtsA PF14450.1 CBK25154.2 - 0.14 11.9 1.8 5.2 6.9 0.7 3.1 3 1 0 3 3 3 0 Cell division protein FtsA Ribosomal_S19 PF00203.16 CBK25155.2 - 7.8e-32 108.7 0.2 1.1e-31 108.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L27e PF01777.13 CBK25156.2 - 1.8e-16 60.0 6.1 2.5e-16 59.5 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBK25156.2 - 5.4e-06 25.9 1.0 9.4e-06 25.1 0.7 1.4 1 0 0 1 1 1 1 KOW motif Herpes_UL51 PF04540.8 CBK25156.2 - 0.062 12.8 0.1 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL51 protein DUF3306 PF11748.3 CBK25156.2 - 0.076 13.6 0.1 0.083 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) zf-LYAR PF08790.6 CBK25157.2 - 3.7e-13 48.9 1.4 3.7e-13 48.9 1.0 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3469 PF11952.3 CBK25157.2 - 0.036 13.7 0.2 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) zf-TRAF PF02176.13 CBK25157.2 - 0.043 14.2 3.1 0.043 14.2 2.1 2.0 3 0 0 3 3 3 0 TRAF-type zinc finger LIM PF00412.17 CBK25157.2 - 0.21 11.6 4.1 0.49 10.4 2.9 1.7 1 1 0 1 1 1 0 LIM domain zf-trcl PF13451.1 CBK25157.2 - 0.36 10.4 0.2 0.36 10.4 0.1 2.8 1 1 1 2 2 2 0 Probable zinc-binding domain zf-C2H2 PF00096.21 CBK25157.2 - 0.41 11.0 4.3 0.92 9.9 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cytochrom_NNT PF03264.9 CBK25157.2 - 0.55 9.6 6.2 0.62 9.4 0.1 2.2 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Elf1 PF05129.8 CBK25157.2 - 0.66 9.7 5.7 1.8 8.3 3.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 CBK25157.2 - 0.98 9.4 4.4 4.4 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 CBK25157.2 - 5 6.8 9.0 0.62 9.7 2.5 2.2 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family NAD_binding_2 PF03446.10 CBK25159.2 - 1.4e-48 164.8 0.9 3.6e-48 163.4 0.7 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBK25159.2 - 3.5e-35 120.7 0.2 5.9e-35 119.9 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CBK25159.2 - 1.2e-11 44.8 0.0 2.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CBK25159.2 - 3.8e-09 36.7 0.2 1.5e-08 34.8 0.1 1.8 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CBK25159.2 - 3.2e-06 26.4 0.0 5.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBK25159.2 - 0.0001 21.7 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CBK25159.2 - 0.0025 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 CBK25159.2 - 0.0084 15.7 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBK25159.2 - 0.0095 16.1 0.0 0.021 15.0 0.0 1.6 1 1 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.11 CBK25159.2 - 0.027 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CBK25159.2 - 0.095 12.4 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 CBK25159.2 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family STT3 PF02516.9 CBK25160.2 - 1.1e-78 265.3 50.9 1.5e-77 261.6 35.3 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit TRAUB PF08164.7 CBK25161.2 - 3.9e-17 62.1 0.2 7.3e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Tox-HNH-HHH PF15637.1 CBK25161.2 - 0.02 14.6 0.5 1.8 8.3 0.1 2.2 1 1 1 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF3788 PF12663.2 CBK25161.2 - 0.03 14.0 1.6 5.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) Prenyltrans PF00432.16 CBK25162.2 - 4.7e-63 208.3 14.1 2.8e-14 52.3 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBK25162.2 - 1.6e-38 131.5 0.0 2e-20 73.2 0.0 3.9 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBK25162.2 - 2.5e-12 46.7 0.0 0.00015 21.7 0.0 4.0 1 1 3 4 4 4 3 Prenyltransferase-like A2M_comp PF07678.9 CBK25162.2 - 0.044 13.0 0.0 8.5 5.5 0.0 2.8 3 1 1 4 4 4 0 A-macroglobulin complement component Mito_carr PF00153.22 CBK25163.2 - 3.1e-38 129.3 2.0 1e-22 79.6 0.1 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein Thioredoxin PF00085.15 CBK25165.2 - 3.3e-05 23.4 0.0 5.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBK25165.2 - 0.019 15.0 0.1 0.06 13.4 0.0 1.9 2 1 0 2 2 2 0 Thioredoxin-like DUF836 PF05768.9 CBK25165.2 - 0.047 13.9 0.1 5.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) HyaE PF07449.6 CBK25165.2 - 0.063 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.15 CBK25166.2 - 0.00099 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glyco_hydro_47 PF01532.15 CBK25167.2 - 4.2e-107 358.6 0.0 5.8e-107 358.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.27 CBK25168.2 - 1.1e-30 104.3 2.9 2e-10 40.1 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.6 CBK25168.2 - 3.2e-11 42.5 0.1 6.1e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 LisH Aconitase PF00330.15 CBK25168.2 - 0.086 11.2 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) KOW PF00467.24 CBK25169.2 - 2.9e-10 39.4 2.4 2.9e-10 39.4 1.7 1.9 2 1 0 2 2 2 1 KOW motif Takusan PF04822.8 CBK25170.2 - 0.038 13.7 0.7 0.038 13.7 0.5 2.1 3 0 0 3 3 3 0 Takusan TPR_2 PF07719.12 CBK25171.2 - 2.4e-10 39.4 0.3 1.5e-06 27.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBK25171.2 - 3.5e-10 38.9 0.2 2e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBK25171.2 - 5.2e-10 38.5 1.1 7e-08 31.7 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBK25171.2 - 3.1e-09 36.6 0.1 3.3e-08 33.3 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBK25171.2 - 1e-07 31.5 0.4 2.9e-07 30.0 0.1 1.9 2 1 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 CBK25171.2 - 8.3e-07 28.3 0.3 0.025 14.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25171.2 - 0.00084 19.3 0.4 0.29 11.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK25171.2 - 0.013 16.0 0.0 3.7 8.4 0.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBK25171.2 - 0.056 13.9 0.9 1.3 9.6 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-CCCH PF00642.19 CBK25172.2 - 1.2e-06 28.0 10.5 0.00095 18.7 1.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBFD_NFYB_HMF PF00808.18 CBK25174.2 - 1.1e-14 54.1 1.8 1.2e-14 54.0 0.5 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBK25174.2 - 2.4e-08 33.9 0.1 3.2e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Fumerase PF05681.9 CBK25175.2 - 5.5e-92 307.6 0.0 8e-92 307.1 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CBK25175.2 - 2.4e-80 268.5 0.0 4e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus MMR_HSR1 PF01926.18 CBK25177.2 - 4.5e-18 65.3 0.0 1.3e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CBK25177.2 - 1.4e-14 53.6 0.0 2.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CBK25177.2 - 6.6e-10 38.4 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBK25177.2 - 4.8e-05 23.2 0.3 0.027 14.3 0.0 2.7 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 CBK25177.2 - 0.00061 20.2 0.0 0.0035 17.8 0.0 2.3 3 1 0 3 3 3 1 Miro-like protein AAA_28 PF13521.1 CBK25177.2 - 0.011 15.6 0.1 0.095 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain GPAT_N PF14829.1 CBK25177.2 - 0.017 14.8 0.2 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_16 PF13191.1 CBK25177.2 - 0.04 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Proteasome PF00227.21 CBK25178.2 - 4.6e-53 179.3 0.0 5.6e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBK25178.2 - 4.8e-15 54.5 0.3 9.7e-15 53.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 CBK25179.2 - 3.7e-15 55.1 0.9 8.5e-06 25.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ThiF PF00899.16 CBK25180.2 - 1.8e-40 137.8 0.2 3.7e-40 136.9 0.1 1.5 2 0 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.4 CBK25180.2 - 1.8e-17 62.4 0.1 4.4e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 CBK25180.2 - 1.3e-15 56.6 0.0 3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein Shikimate_DH PF01488.15 CBK25180.2 - 0.00027 21.0 0.1 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBK25180.2 - 0.0013 18.9 0.1 0.0026 17.9 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 CBK25180.2 - 0.015 15.6 0.4 0.28 11.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HRDC PF00570.18 CBK25181.2 - 1.4e-11 43.9 0.1 3.2e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain AFG1_ATPase PF03969.11 CBK25183.2 - 3.4e-93 312.3 0.0 2.7e-92 309.3 0.1 1.9 1 1 1 2 2 2 1 AFG1-like ATPase AAA PF00004.24 CBK25183.2 - 1.3e-08 35.0 0.0 5.1e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBK25183.2 - 5.5e-05 23.0 0.0 0.0005 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBK25183.2 - 0.00015 21.8 0.0 0.2 11.6 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CBK25183.2 - 0.00038 20.4 0.0 0.32 10.9 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 CBK25183.2 - 0.0013 18.8 0.1 0.0053 16.9 0.0 2.1 2 1 0 2 2 2 1 RNA helicase Bac_DnaA PF00308.13 CBK25183.2 - 0.0016 18.1 0.3 0.0083 15.7 0.0 2.2 2 1 0 2 2 2 1 Bacterial dnaA protein UvrD-helicase PF00580.16 CBK25183.2 - 0.0026 17.0 0.2 0.0099 15.2 0.1 1.7 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain NACHT PF05729.7 CBK25183.2 - 0.0048 16.5 0.0 0.069 12.8 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 CBK25183.2 - 0.005 16.9 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBK25183.2 - 0.088 11.8 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CBK25183.2 - 0.12 12.6 0.0 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 ABC transporter WD40 PF00400.27 CBK25184.2 - 1.3e-07 31.1 4.0 3e-06 26.8 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.3 CBK25184.2 - 9.7e-05 20.6 0.4 0.00033 18.9 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.6 CBK25184.2 - 0.0088 15.2 0.0 0.084 12.0 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split U1snRNP70_N PF12220.3 CBK25185.2 - 0.096 13.0 0.1 0.1 12.9 0.1 1.0 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PIF1 PF05970.9 CBK25186.2 - 2.1e-57 194.7 0.6 1.5e-43 149.1 0.1 2.3 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CBK25186.2 - 1.7e-15 57.1 0.0 3.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBK25186.2 - 9.5e-08 32.2 0.1 3.8e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBK25186.2 - 0.00018 21.7 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 CBK25186.2 - 0.00034 20.3 0.0 0.00078 19.1 0.0 1.6 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 CBK25186.2 - 0.0019 18.1 0.8 0.033 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBK25186.2 - 0.0076 15.9 0.1 0.029 14.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CBK25186.2 - 0.012 13.4 0.4 0.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.4 CBK25186.2 - 0.03 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CBK25186.2 - 0.047 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Aminotran_5 PF00266.14 CBK25187.2 - 9e-45 152.9 0.0 1.2e-43 149.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.15 CBK25187.2 - 6e-20 71.4 0.0 1.3e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 PP-loop family zf-XS PF03470.9 CBK25187.2 - 0.023 14.7 0.1 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 XS zinc finger domain Sporozoite_P67 PF05642.6 CBK25187.2 - 0.087 10.6 4.5 0.14 9.9 3.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HPD PF05044.7 CBK25187.2 - 0.14 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain RR_TM4-6 PF06459.7 CBK25187.2 - 2.1 8.1 8.7 3.7 7.3 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.6 CBK25187.2 - 2.3 8.0 14.4 4.5 7.1 10.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rifin_STEVOR PF02009.11 CBK25188.2 - 0.0011 18.6 0.4 0.0013 18.5 0.2 1.1 1 0 0 1 1 1 1 Rifin/stevor family Use1 PF09753.4 CBK25188.2 - 0.032 13.6 0.3 0.032 13.6 0.2 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF3753 PF12575.3 CBK25188.2 - 0.048 13.4 0.4 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) UPF0233 PF06781.7 CBK25188.2 - 0.048 13.2 0.1 0.05 13.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) L1R_F9L PF02442.12 CBK25188.2 - 0.055 12.9 0.1 0.056 12.9 0.1 1.0 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses DUF912 PF06024.7 CBK25188.2 - 0.062 13.3 0.6 0.068 13.2 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Viral_Beta_CD PF04530.7 CBK25188.2 - 0.14 12.2 0.2 0.14 12.2 0.1 1.0 1 0 0 1 1 1 0 Viral Beta C/D like family PsbM PF05151.7 CBK25188.2 - 0.59 9.7 7.0 0.88 9.2 4.8 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Epimerase PF01370.16 CBK25189.2 - 7.7e-45 153.1 0.0 9.4e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBK25189.2 - 7.3e-11 41.4 0.0 8.9e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CBK25189.2 - 9.6e-08 31.2 0.0 7.3e-05 21.8 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 CBK25189.2 - 4.4e-07 28.8 0.0 1.8e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBK25189.2 - 0.0017 17.3 0.0 0.67 8.7 0.0 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 CBK25189.2 - 0.006 15.9 0.9 0.0099 15.2 0.6 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rad1 PF02144.11 CBK25190.2 - 9.7e-14 50.7 3.7 1.7e-13 50.0 2.5 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_N PF00705.13 CBK25190.2 - 0.0028 17.1 1.1 0.0038 16.7 0.8 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Hus1 PF04005.7 CBK25190.2 - 0.022 13.7 0.3 0.028 13.3 0.2 1.1 1 0 0 1 1 1 0 Hus1-like protein TLD PF07534.11 CBK25191.2 - 7.8e-16 58.3 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 TLD Metallophos PF00149.23 CBK25192.2 - 1.9e-41 141.6 0.1 2.3e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tom22 PF04281.8 CBK25193.2 - 0.0019 17.7 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HSP70 PF00012.15 CBK25194.2 - 6e-13 47.5 0.3 1.2e-07 30.0 0.0 2.7 3 1 0 3 3 3 2 Hsp70 protein FF PF01846.14 CBK25195.2 - 4.7e-20 71.2 0.1 1.7e-08 34.2 0.0 5.0 5 0 0 5 5 5 3 FF domain WW PF00397.21 CBK25195.2 - 5.1e-10 39.0 10.0 2.8e-05 23.8 1.2 2.8 2 0 0 2 2 2 2 WW domain AhpC-TSA PF00578.16 CBK25198.2 - 2.1e-45 153.4 0.5 1.3e-38 131.5 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.15 CBK25198.2 - 5.3e-27 93.5 0.7 9.2e-27 92.7 0.5 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 CBK25198.2 - 1.4e-21 76.5 0.2 5.9e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.4 CBK25198.2 - 6.8e-12 44.8 0.0 1.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.1 CBK25198.2 - 4e-09 36.4 0.1 8.3e-06 25.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CBK25198.2 - 5e-07 29.3 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBK25198.2 - 1.6e-06 28.2 0.7 2.9e-05 24.2 0.2 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBK25198.2 - 0.00037 20.4 0.1 0.00098 19.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Metallophos PF00149.23 CBK25199.2 - 5e-12 45.6 3.1 1.4e-11 44.2 2.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK25199.2 - 2.1e-08 34.1 0.1 6.7e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 CBK25199.2 - 0.013 14.6 0.0 0.051 12.7 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily INCENP_N PF12178.3 CBK25200.2 - 0.019 14.5 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Arf PF00025.16 CBK25201.2 - 2.5e-72 241.7 0.0 3e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBK25201.2 - 7.6e-13 47.9 0.6 1.9e-09 36.7 0.2 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBK25201.2 - 1.7e-12 47.0 0.0 2e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBK25201.2 - 3.3e-12 45.9 0.0 3.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBK25201.2 - 2.2e-10 40.0 0.0 2.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK25201.2 - 5.5e-09 36.5 0.0 7.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK25201.2 - 1.1e-05 25.3 0.1 2.5e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK25201.2 - 0.0068 15.6 0.7 0.032 13.5 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBK25201.2 - 0.11 11.8 0.0 0.45 9.9 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Adap_comp_sub PF00928.16 CBK25202.2 - 2.2e-36 125.3 0.0 2.9e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBK25202.2 - 2.8e-06 27.0 0.5 4.2e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HSP70 PF00012.15 CBK25203.2 - 8.2e-45 152.8 0.0 1.1e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK25203.2 - 1.2e-07 30.6 0.2 3.8e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBK25203.2 - 0.012 14.5 0.0 0.083 11.8 0.0 2.1 1 1 0 1 1 1 0 StbA protein FancD2 PF14631.1 CBK25204.2 - 6.7e-22 76.5 0.7 1.7e-21 75.2 0.9 1.3 2 0 0 2 2 2 1 Fanconi anaemia protein FancD2 nuclease FancD2 PF14631.1 CBK25205.2 - 4.8e-11 40.5 0.0 1.1e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Tenui_NCP PF04876.7 CBK25205.2 - 0.068 12.7 0.0 0.2 11.1 0.0 1.6 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Limkain-b1 PF11608.3 CBK25205.2 - 0.14 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Fumerase PF05681.9 CBK25206.2 - 1.3e-91 306.4 0.0 2.3e-91 305.6 0.0 1.4 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CBK25206.2 - 4.6e-80 267.6 0.0 9.8e-80 266.5 0.0 1.5 1 0 0 1 1 1 1 Fumarase C-terminus MIP-T3 PF10243.4 CBK25206.2 - 0.13 10.6 27.0 0.18 10.2 18.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CENP-T PF15511.1 CBK25206.2 - 0.61 9.2 20.0 1 8.5 13.8 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Neur_chan_memb PF02932.11 CBK25206.2 - 2.2 8.0 4.0 4.1 7.2 2.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Daxx PF03344.10 CBK25206.2 - 2.3 6.5 28.9 3.6 5.9 20.0 1.2 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CBK25206.2 - 6.6 4.7 30.2 9.5 4.2 20.9 1.2 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.5 CBK25206.2 - 7.6 5.4 32.9 12 4.8 22.8 1.3 1 0 0 1 1 1 0 BUD22 OCC1 PF15506.1 CBK25206.2 - 9.5 6.1 8.9 5.3 6.9 2.4 2.9 3 0 0 3 3 3 0 OCC1 family UQ_con PF00179.21 CBK25207.2 - 1.2e-16 60.4 0.2 1.5e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C PF00481.16 CBK25208.2 - 1.5e-21 76.9 0.0 1.9e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C REV PF00424.13 CBK25208.2 - 1 9.3 5.5 2.4 8.1 3.6 1.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) AAT PF03417.11 CBK25209.2 - 8.2e-25 87.5 0.0 1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Myb_DNA-binding PF00249.26 CBK25210.2 - 4.7e-43 145.0 7.3 1.9e-17 63.0 0.7 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK25210.2 - 2e-36 123.9 9.8 7.8e-17 61.1 0.4 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Collagen PF01391.13 CBK25210.2 - 9.7e-06 25.0 17.6 2.5e-05 23.6 12.2 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rap1_C PF11626.3 CBK25210.2 - 7e-05 22.6 6.4 0.32 10.9 0.1 3.4 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CBK25210.2 - 0.0018 18.3 7.3 0.11 12.6 0.6 3.5 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Ribosomal_S24e PF01282.14 CBK25211.2 - 1.2e-27 95.5 0.0 1.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e PSS PF03034.10 CBK25212.2 - 2e-96 322.6 15.4 2e-96 322.6 10.7 2.0 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF1516 PF07457.6 CBK25212.2 - 0.00085 19.3 0.7 0.0031 17.5 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1516) Secretin_N_2 PF07655.8 CBK25212.2 - 0.0065 16.8 0.2 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain Spc7_C2 PF15577.1 CBK25213.2 - 0.11 12.0 0.1 8.5 6.1 0.0 3.0 3 0 0 3 3 3 0 Spc7_C2 DUF1136 PF06582.7 CBK25213.2 - 0.61 9.8 2.4 11 5.8 0.1 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) DSPn PF14671.1 CBK25214.2 - 4.1e-43 146.7 3.7 1.5e-41 141.6 1.2 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CBK25214.2 - 2.9e-15 56.0 0.0 8.9e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBK25214.2 - 1e-06 28.2 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBK25214.2 - 0.0025 17.8 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1700 PF08006.6 CBK25214.2 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Y_phosphatase3 PF13350.1 CBK25214.2 - 0.027 14.7 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family YlqD PF11068.3 CBK25215.2 - 0.029 14.3 0.1 0.031 14.3 0.1 1.0 1 0 0 1 1 1 0 YlqD protein KIX PF02172.11 CBK25215.2 - 0.073 13.1 0.1 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 KIX domain LRR_4 PF12799.2 CBK25216.2 - 1.9e-16 59.2 5.9 3.3e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBK25216.2 - 5.8e-12 45.1 6.4 3e-07 30.0 0.3 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBK25216.2 - 1.6e-06 27.3 16.8 0.017 15.0 0.1 5.8 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CBK25216.2 - 0.0013 18.5 10.0 6.3 7.4 0.0 5.4 5 1 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CBK25216.2 - 0.096 12.8 12.1 10 6.5 0.1 5.2 4 1 1 5 5 5 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.9 CBK25217.2 - 2.1e-11 44.1 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CBFD_NFYB_HMF PF00808.18 CBK25218.2 - 4.5e-06 26.6 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBK25218.2 - 0.0028 17.8 0.1 0.0052 16.9 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF3901 PF13040.1 CBK25218.2 - 0.021 14.0 0.5 0.054 12.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) HHH_6 PF14579.1 CBK25218.2 - 0.026 14.5 0.2 0.65 10.0 0.0 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif PHD PF00628.24 CBK25219.2 - 2.8e-09 36.5 4.7 4.4e-09 35.8 3.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CBK25219.2 - 1.3e-05 25.2 0.5 2.2e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CBK25219.2 - 0.0032 16.7 0.2 0.0032 16.7 0.1 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 CBK25219.2 - 0.006 16.5 0.8 0.011 15.7 0.2 1.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-RanBP PF00641.13 CBK25219.2 - 0.014 14.4 1.1 0.25 10.4 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.2 CBK25219.2 - 0.083 13.0 1.3 0.19 11.8 0.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CBK25219.2 - 0.096 12.5 1.0 0.18 11.6 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBK25219.2 - 3.2 7.6 7.7 2.2 8.1 1.7 2.6 2 0 0 2 2 2 0 Ring finger domain CHCH PF06747.8 CBK25221.2 - 0.0077 16.1 7.1 0.015 15.2 4.9 1.5 1 0 0 1 1 1 1 CHCH domain SR-25 PF10500.4 CBK25221.2 - 0.25 10.8 19.9 0.39 10.1 13.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CBK25221.2 - 0.9 9.3 16.8 1.1 9.0 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4106 PF13388.1 CBK25221.2 - 8.6 5.2 14.2 13 4.6 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4366 PF14283.1 CBK25222.2 - 0.0035 16.7 0.3 0.004 16.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Rsd_AlgQ PF04353.8 CBK25222.2 - 0.018 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CYSTM PF12734.2 CBK25222.2 - 0.019 14.9 0.2 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF4131 PF13567.1 CBK25222.2 - 0.13 11.6 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fcf1 PF04900.7 CBK25223.2 - 1.1e-40 137.8 0.8 1.1e-40 137.8 0.6 1.9 2 0 0 2 2 2 1 Fcf1 Cpn60_TCP1 PF00118.19 CBK25224.2 - 2.6e-148 494.6 0.1 3.1e-148 494.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec7 PF01369.15 CBK25225.2 - 1.3e-63 214.0 2.6 2.3e-63 213.3 0.0 2.7 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 CBK25225.2 - 1.2e-33 115.8 7.8 1.2e-33 115.8 5.4 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CBK25225.2 - 1.7e-26 91.5 3.9 2.5e-23 81.3 0.0 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) Asparaginase_2 PF01112.13 CBK25226.2 - 6.4e-15 54.6 0.0 1.8e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Asparaginase CHAT PF12770.2 CBK25226.2 - 0.018 14.1 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 CHAT domain PP2C PF00481.16 CBK25227.2 - 7.8e-61 205.6 0.1 8.7e-61 205.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBK25227.2 - 2.7e-05 23.9 0.2 0.00021 21.0 0.2 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) SAM_1 PF00536.25 CBK25229.2 - 0.098 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4137 PF13593.1 CBK25230.2 - 3.6e-34 118.2 24.3 3.9e-34 118.1 16.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 CBK25230.2 - 1.5e-11 44.0 17.7 1.5e-11 44.0 12.3 1.6 2 1 0 2 2 2 1 Sodium Bile acid symporter family Pro_isomerase PF00160.16 CBK25231.2 - 5e-43 146.9 0.0 5.6e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TMF_DNA_bd PF12329.3 CBK25232.2 - 0.0028 17.4 1.8 0.0028 17.4 1.3 3.0 2 1 0 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 CBK25232.2 - 0.015 14.5 1.2 0.015 14.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.3 CBK25232.2 - 0.015 15.1 17.6 0.017 15.0 3.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 CBK25232.2 - 0.022 14.7 16.3 0.022 14.7 3.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Phage_GP20 PF06810.6 CBK25232.2 - 0.039 13.4 11.7 0.36 10.2 1.6 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 CBK25232.2 - 0.078 12.8 0.7 0.078 12.8 0.5 3.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF641 PF04859.7 CBK25232.2 - 0.11 12.2 11.7 0.12 12.0 0.5 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Tmemb_cc2 PF10267.4 CBK25232.2 - 0.13 10.8 18.2 0.23 10.0 11.5 1.8 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AAA_13 PF13166.1 CBK25232.2 - 0.21 10.0 13.0 0.25 9.7 9.0 1.0 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.6 CBK25232.2 - 0.24 9.8 15.8 2.8 6.3 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ATG16 PF08614.6 CBK25232.2 - 0.42 10.3 18.6 0.86 9.3 4.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4298 PF14131.1 CBK25232.2 - 0.43 10.4 7.7 0.2 11.5 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Occludin_ELL PF07303.8 CBK25232.2 - 0.46 11.2 9.0 0.56 10.9 0.8 2.2 2 0 0 2 2 2 0 Occludin homology domain COG5 PF10392.4 CBK25232.2 - 0.63 10.0 8.4 0.91 9.4 0.1 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.6 CBK25232.2 - 0.67 8.5 18.7 0.25 9.9 3.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2935 PF11155.3 CBK25232.2 - 0.93 9.5 5.9 4.2 7.4 3.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) GAS PF13851.1 CBK25232.2 - 1 8.5 21.1 0.87 8.7 3.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBK25232.2 - 1.3 8.5 22.8 1.4 8.4 6.4 2.1 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 CBK25232.2 - 1.3 8.8 21.7 3.4 7.5 14.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.7 CBK25232.2 - 1.4 8.2 11.6 5.1 6.3 3.9 2.4 1 1 1 2 2 2 0 PspA/IM30 family Bacillus_HBL PF05791.6 CBK25232.2 - 1.4 8.2 8.1 1.9 7.7 1.0 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.6 CBK25232.2 - 1.5 8.5 17.8 0.39 10.4 2.8 2.4 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 CBK25232.2 - 1.6 8.5 17.8 0.71 9.6 1.7 3.0 2 1 1 3 3 3 0 Prefoldin subunit Allexi_40kDa PF05549.6 CBK25232.2 - 1.6 7.9 10.4 2 7.6 2.8 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein ORF6C PF10552.4 CBK25232.2 - 1.8 8.3 11.9 1.6 8.5 0.5 2.8 1 1 2 3 3 3 0 ORF6C domain DivIVA PF05103.8 CBK25232.2 - 1.9 8.5 16.5 4.7 7.2 3.9 2.6 1 1 1 2 2 2 0 DivIVA protein APG6 PF04111.7 CBK25232.2 - 1.9 7.4 20.7 2.1 7.3 3.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 CBK25232.2 - 2 8.4 17.4 3.5 7.6 12.1 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Muted PF14942.1 CBK25232.2 - 2.3 8.1 14.6 4.7 7.0 4.2 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Tropomyosin_1 PF12718.2 CBK25232.2 - 2.8 7.7 20.9 3.3 7.5 4.7 2.2 2 0 0 2 2 2 0 Tropomyosin like Vps51 PF08700.6 CBK25232.2 - 3 7.7 12.8 36 4.2 0.1 3.8 2 1 1 3 3 3 0 Vps51/Vps67 DUF972 PF06156.8 CBK25232.2 - 3.3 8.0 19.3 3.1 8.2 2.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 CBK25232.2 - 3.5 7.8 13.7 11 6.1 0.2 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 CBK25232.2 - 3.6 7.1 20.1 1.1 8.8 6.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CBK25232.2 - 5 4.8 14.0 11 3.6 9.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 CBK25232.2 - 6.1 5.7 7.1 10 5.0 5.0 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ERM PF00769.14 CBK25232.2 - 8.6 5.8 20.1 0.63 9.5 4.0 2.1 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DUF4164 PF13747.1 CBK25232.2 - 9.8 6.3 11.2 1.3 9.2 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Myosin_tail_1 PF01576.14 CBK25233.2 - 0.00029 18.7 22.1 0.00035 18.4 15.3 1.1 1 0 0 1 1 1 1 Myosin tail Fzo_mitofusin PF04799.8 CBK25233.2 - 0.013 14.8 19.2 0.25 10.7 4.7 2.4 1 1 1 2 2 2 0 fzo-like conserved region Atg14 PF10186.4 CBK25233.2 - 0.046 12.6 17.7 0.065 12.1 12.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Erythro_esteras PF05139.9 CBK25233.2 - 0.11 11.6 2.0 0.14 11.3 1.4 1.2 1 0 0 1 1 1 0 Erythromycin esterase GBP_C PF02841.9 CBK25233.2 - 0.2 10.8 24.4 0.54 9.4 16.4 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Baculo_PEP_C PF04513.7 CBK25233.2 - 0.22 11.3 11.1 4.6 7.0 1.9 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med21 PF11221.3 CBK25233.2 - 0.36 10.8 19.8 0.65 9.9 11.4 2.6 1 1 2 3 3 3 0 Subunit 21 of Mediator complex Lectin_N PF03954.9 CBK25233.2 - 0.38 10.1 11.7 0.36 10.2 1.5 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF3106 PF11304.3 CBK25233.2 - 0.52 10.7 10.0 1 9.8 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Phage_lysis PF03245.8 CBK25233.2 - 0.64 10.0 9.2 1.3 9.0 6.2 1.7 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein ApoO PF09769.4 CBK25233.2 - 0.8 9.3 3.7 1.4 8.5 2.5 1.5 1 0 0 1 1 1 0 Apolipoprotein O Fib_alpha PF08702.5 CBK25233.2 - 0.98 9.5 18.5 0.46 10.6 10.7 1.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.3 CBK25233.2 - 1.3 8.1 12.8 0.5 9.5 7.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HlyD PF00529.15 CBK25233.2 - 1.7 7.8 13.7 3 7.0 9.5 1.5 1 1 0 1 1 1 0 HlyD family secretion protein ATG16 PF08614.6 CBK25233.2 - 2.6 7.8 27.7 0.94 9.2 7.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) OEP PF02321.13 CBK25233.2 - 3.9 7.0 18.2 0.56 9.7 3.0 2.2 1 1 1 2 2 2 0 Outer membrane efflux protein Cortex-I_coil PF09304.5 CBK25233.2 - 4.1 7.4 29.4 4.3 7.4 10.2 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 CBK25233.2 - 6.2 4.5 16.1 9.9 3.8 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2018 PF09442.5 CBK25233.2 - 7.5 7.2 15.4 0.58 10.7 1.4 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF2018) RmuC PF02646.11 CBK25233.2 - 9.7 4.9 20.5 9.4 4.9 5.8 2.5 2 1 1 3 3 3 0 RmuC family Acetyltransf_1 PF00583.19 CBK25234.2 - 0.00085 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CBK25234.2 - 0.0028 17.8 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBK25234.2 - 0.014 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos PF00149.23 CBK25235.2 - 2.9e-42 144.3 0.2 4.1e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBK25235.2 - 0.0033 17.2 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 CBK25236.2 - 2.3e-41 141.6 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25236.2 - 1.8e-17 63.2 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK25236.2 - 0.035 13.0 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like GMAP PF06540.6 CBK25236.2 - 0.15 11.8 0.3 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Galanin message associated peptide (GMAP) Hist_deacetyl PF00850.14 CBK25237.2 - 1.9e-66 224.4 0.0 2.3e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Tfb4 PF03850.9 CBK25238.2 - 1.2e-06 27.9 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 MFS_1 PF07690.11 CBK25239.2 - 6.3e-18 64.6 10.1 1.6e-14 53.4 2.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK25239.2 - 1.3e-06 27.2 5.1 2.3e-05 23.1 0.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter GTP_EFTU PF00009.22 CBK25240.2 - 3.7e-60 202.5 0.0 5e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBK25240.2 - 5.2e-29 100.3 0.0 1.1e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBK25240.2 - 1.5e-16 60.2 3.0 4e-16 58.8 2.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBK25240.2 - 8.8e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBK25240.2 - 7.3e-05 22.3 1.4 0.00023 20.7 1.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CBK25240.2 - 0.0067 16.9 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 CBK25240.2 - 0.045 13.2 0.3 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored_q6 PF01058.17 CBK25241.2 - 7.7e-23 80.5 0.0 1.3e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit SF-assemblin PF06705.6 CBK25242.2 - 0.12 11.5 0.1 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin HA2 PF04408.18 CBK25243.2 - 6.1e-22 77.5 0.0 1.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK25243.2 - 1.3e-18 66.8 0.0 2.3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK25243.2 - 1.7e-12 47.0 0.0 7.4e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK25243.2 - 6.1e-05 22.5 0.3 0.0019 17.6 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK25244.2 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK25244.2 - 0.0014 18.3 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CBK25244.2 - 0.0017 17.3 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CBK25244.2 - 0.002 18.4 1.2 0.0028 18.0 0.7 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBK25244.2 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CBK25244.2 - 0.0044 16.5 0.2 0.0075 15.7 0.1 1.5 1 1 0 1 1 1 1 FtsK/SpoIIIE family KaiC PF06745.8 CBK25244.2 - 0.0096 15.0 0.1 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 CBK25244.2 - 0.011 16.0 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 CBK25244.2 - 0.012 15.4 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK25244.2 - 0.018 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 CBK25244.2 - 0.022 13.8 1.0 0.11 11.5 0.0 2.3 1 1 2 3 3 3 0 Zeta toxin AAA_25 PF13481.1 CBK25244.2 - 0.038 13.4 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBK25244.2 - 0.043 13.2 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.11 CBK25244.2 - 0.064 12.4 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 CBK25244.2 - 0.074 12.9 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CBK25244.2 - 0.075 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CBK25244.2 - 0.075 12.4 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CBK25244.2 - 0.081 12.1 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CBK25244.2 - 0.09 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein FrhB_FdhB_N PF04422.8 CBK25244.2 - 0.11 12.4 0.1 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term SRP54 PF00448.17 CBK25244.2 - 0.12 11.7 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 CBK25244.2 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CBK25244.2 - 0.24 11.7 0.9 0.35 11.1 0.2 1.8 2 1 0 2 2 2 0 AAA domain HSP20 PF00011.16 CBK25245.2 - 3.1e-27 94.3 2.9 3.7e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3716 PF12511.3 CBK25245.2 - 0.063 12.9 1.0 0.47 10.1 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF104 PF01954.11 CBK25245.2 - 0.089 12.8 1.8 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK25245.2 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Nol1_Nop2_Fmu PF01189.12 CBK25246.2 - 3.3e-10 39.7 0.0 6.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBK25246.2 - 0.0076 16.2 0.0 0.0085 16.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0542 PF15086.1 CBK25246.2 - 0.61 9.8 3.6 1.6 8.5 2.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CPSase_L_D2 PF02786.12 CBK25247.2 - 2.7e-72 242.4 0.0 4.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK25247.2 - 6.2e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK25247.2 - 7.8e-35 119.1 0.0 1.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK25247.2 - 2.8e-18 65.3 0.2 5.9e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK25247.2 - 1.8e-09 36.7 0.0 4.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK25247.2 - 3.8e-08 32.8 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK25247.2 - 4.5e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK25247.2 - 7.7e-08 31.9 0.1 3.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK25247.2 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK25247.2 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK25247.2 - 0.0024 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK25247.2 - 0.0037 16.9 0.4 0.012 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK25247.2 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK25247.2 - 0.015 15.6 0.0 0.46 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK25247.2 - 0.041 13.9 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK25247.2 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK25247.2 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK25247.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DNA_pol_E_B PF04042.11 CBK25248.2 - 4.3e-15 55.5 0.0 5.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COPIIcoated_ERV PF07970.7 CBK25249.2 - 9.1e-17 61.4 0.9 9.8e-17 61.3 0.6 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Shisa PF13908.1 CBK25250.2 - 0.0001 22.5 1.4 0.0002 21.5 1.0 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.6 CBK25250.2 - 0.0069 16.0 0.7 0.013 15.1 0.5 1.4 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein TMEM154 PF15102.1 CBK25250.2 - 0.018 14.7 1.1 0.045 13.4 0.8 1.7 1 1 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.1 CBK25250.2 - 0.066 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 SCIMP protein GRP PF07172.6 CBK25250.2 - 0.54 10.7 12.8 1.5 9.3 6.8 2.2 2 0 0 2 2 2 0 Glycine rich protein family TPT PF03151.11 CBK25251.2 - 2.6e-05 23.9 8.9 2.6e-05 23.9 6.2 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CBK25251.2 - 0.018 15.0 23.3 1.3 9.0 3.6 3.7 2 2 0 2 2 2 0 EamA-like transporter family UPF0139 PF03669.8 CBK25251.2 - 0.18 11.3 1.3 2.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) CPSase_L_D2 PF02786.12 CBK25252.2 - 2.7e-72 242.4 0.0 4.4e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBK25252.2 - 6.2e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBK25252.2 - 7.8e-35 119.1 0.0 1.7e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBK25252.2 - 2.8e-18 65.3 0.2 5.9e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CBK25252.2 - 1.8e-09 36.7 0.0 4.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBK25252.2 - 3.8e-08 32.8 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.1 CBK25252.2 - 4.5e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBK25252.2 - 7.7e-08 31.9 0.1 3.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBK25252.2 - 6.5e-05 22.3 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBK25252.2 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CBK25252.2 - 0.0024 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CBK25252.2 - 0.0037 16.9 0.4 0.012 15.2 0.1 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein DUF2118 PF09891.4 CBK25252.2 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CBK25252.2 - 0.015 15.6 0.0 0.46 10.8 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 CBK25252.2 - 0.041 13.9 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 CBK25252.2 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.8 CBK25252.2 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATP-grasp_3 PF02655.9 CBK25252.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain HSP20 PF00011.16 CBK25253.2 - 3.1e-27 94.3 2.9 3.7e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF3716 PF12511.3 CBK25253.2 - 0.063 12.9 1.0 0.47 10.1 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) DUF104 PF01954.11 CBK25253.2 - 0.089 12.8 1.8 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF104 MmlI PF09448.5 CBK25253.2 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase AAA_22 PF13401.1 CBK25254.2 - 0.0014 18.8 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBK25254.2 - 0.0015 18.2 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CBK25254.2 - 0.0017 17.3 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CBK25254.2 - 0.002 18.4 1.2 0.0028 18.0 0.7 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBK25254.2 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CBK25254.2 - 0.0044 16.5 0.2 0.0075 15.7 0.1 1.5 1 1 0 1 1 1 1 FtsK/SpoIIIE family KaiC PF06745.8 CBK25254.2 - 0.0096 15.0 0.1 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.22 CBK25254.2 - 0.01 16.1 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 CBK25254.2 - 0.012 15.4 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 CBK25254.2 - 0.018 14.5 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 CBK25254.2 - 0.02 13.9 1.0 0.11 11.5 0.0 2.4 1 1 2 3 3 3 0 Zeta toxin AAA_25 PF13481.1 CBK25254.2 - 0.038 13.3 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBK25254.2 - 0.043 13.2 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.11 CBK25254.2 - 0.05 12.8 0.2 0.066 12.4 0.2 1.4 1 1 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 CBK25254.2 - 0.075 12.9 0.1 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBK25254.2 - 0.076 12.4 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CBK25254.2 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBK25254.2 - 0.083 12.0 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CBK25254.2 - 0.09 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein FrhB_FdhB_N PF04422.8 CBK25254.2 - 0.1 12.5 0.1 0.15 11.9 0.1 1.4 1 1 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term SRP54 PF00448.17 CBK25254.2 - 0.12 11.7 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 CBK25254.2 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 CBK25254.2 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain HA2 PF04408.18 CBK25255.2 - 6.1e-22 77.5 0.0 1.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK25255.2 - 1.3e-18 66.8 0.0 2.3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBK25255.2 - 1.9e-12 46.8 0.0 7.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK25255.2 - 3.7e-05 23.2 0.4 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase LRR_8 PF13855.1 CBK25256.2 - 0.0033 17.1 1.0 1.2 8.9 0.1 2.8 2 0 0 2 2 2 2 Leucine rich repeat hSac2 PF12456.3 CBK25256.2 - 0.11 11.8 0.4 2.7 7.3 0.0 2.8 1 1 2 3 3 3 0 Inositol phosphatase ACR_tran PF00873.14 CBK25257.2 - 0.12 9.7 0.0 0.2 9.0 0.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TK PF00265.13 CBK25258.2 - 0.082 12.4 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Ribosomal_S19 PF00203.16 CBK25260.2 - 5.1e-32 109.3 0.2 6.3e-32 109.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 SMC_N PF02463.14 CBK25261.2 - 1.1e-67 227.5 0.0 1.8e-67 226.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK25261.2 - 8.6e-26 90.2 0.1 2.2e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK25261.2 - 9.8e-16 58.5 1.1 4.9e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBK25261.2 - 4.1e-15 56.6 6.6 4.1e-15 56.6 4.6 5.7 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CBK25261.2 - 1.7e-05 24.2 0.0 3.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBK25261.2 - 3.9e-05 22.8 3.9 3.9e-05 22.8 2.7 2.2 2 1 1 3 3 3 1 AAA ATPase domain GAS PF13851.1 CBK25261.2 - 0.00073 18.7 1.3 0.00073 18.7 0.9 6.6 4 2 2 6 6 5 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CBK25261.2 - 0.0033 16.6 11.0 0.13 11.4 0.3 3.8 3 1 0 3 3 3 2 Reovirus sigma C capsid protein TPR_8 PF13181.1 CBK25261.2 - 0.013 15.1 1.6 14 5.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 CBK25261.2 - 0.033 14.4 0.0 0.033 14.4 0.0 5.2 3 2 1 4 4 4 0 ABC transporter YqjK PF13997.1 CBK25261.2 - 0.062 13.4 3.0 5.2 7.3 0.2 3.7 3 0 0 3 3 3 0 YqjK-like protein Baculo_PEP_C PF04513.7 CBK25261.2 - 4 7.2 12.8 2.9 7.7 0.2 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 CBK25263.2 - 4.6e-22 78.4 0.1 5.4e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25263.2 - 4.1e-11 42.4 0.0 4.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBK25263.2 - 0.00055 19.0 0.0 0.00076 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBK25263.2 - 0.025 13.5 0.0 0.29 10.0 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBK25263.2 - 0.084 11.6 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L27e PF01777.13 CBK25264.2 - 1e-09 38.3 1.1 1.3e-09 38.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family B56 PF01603.15 CBK25264.2 - 0.045 12.3 0.1 0.049 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Aminotran_4 PF01063.14 CBK25266.2 - 3.1e-19 69.3 0.0 3.9e-19 69.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class IV HK PF02110.10 CBK25268.2 - 2.8e-85 285.4 2.7 3.2e-85 285.2 1.9 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 CBK25268.2 - 3.3e-07 29.7 0.4 4.2e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 CBK25268.2 - 0.00011 21.6 0.3 0.00013 21.3 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate kinase KOW PF00467.24 CBK25269.2 - 2.9e-10 39.4 2.4 2.9e-10 39.4 1.7 1.9 2 1 0 2 2 2 1 KOW motif TPD PF14811.1 CBK25270.2 - 3.3e-11 42.8 0.0 6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif DUF2608 PF11019.3 CBK25270.2 - 0.0076 15.2 0.2 0.16 10.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2608) MPP6 PF10175.4 CBK25272.2 - 1.7e-06 28.3 2.5 2.6e-06 27.7 1.7 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 P2 PF07194.6 CBK25272.2 - 0.016 15.0 0.2 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 P2 response regulator binding domain DUF4524 PF15025.1 CBK25272.2 - 0.095 12.1 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Agouti PF05039.7 CBK25272.2 - 0.28 11.5 4.1 0.22 11.9 0.3 2.0 1 1 1 2 2 2 0 Agouti protein WD40 PF00400.27 CBK25273.2 - 0.00052 19.8 1.5 0.0041 16.9 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.1 CBK25273.2 - 0.00099 18.6 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.9 CBK25273.2 - 0.0014 17.5 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region BRCT PF00533.21 CBK25274.2 - 1.5e-08 34.6 0.1 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Glyco_hydro_38 PF01074.17 CBK25275.2 - 3.2e-76 256.1 8.6 5.1e-76 255.5 5.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CBK25275.2 - 1.5e-51 175.6 0.9 2.2e-51 175.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CBK25275.2 - 2e-20 72.8 0.2 5e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain AAA PF00004.24 CBK25276.2 - 8.8e-43 145.6 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBK25276.2 - 7e-08 32.5 0.1 2.2e-07 30.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBK25276.2 - 3.7e-07 30.3 0.0 1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBK25276.2 - 5.3e-07 29.8 0.2 0.00025 21.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBK25276.2 - 3.3e-06 26.8 2.1 1.1e-05 25.2 0.2 2.9 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBK25276.2 - 6.1e-06 25.4 0.0 1.3e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBK25276.2 - 7.1e-06 25.5 1.0 0.018 14.4 0.2 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 CBK25276.2 - 0.00055 19.6 0.1 0.0012 18.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CBK25276.2 - 0.0008 20.2 1.8 0.0013 19.5 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CBK25276.2 - 0.00082 19.6 0.0 0.00082 19.6 0.0 2.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBK25276.2 - 0.00084 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 CBK25276.2 - 0.001 18.2 0.2 0.058 12.5 0.0 2.4 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.17 CBK25276.2 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CBK25276.2 - 0.0013 17.5 0.4 0.0032 16.2 0.2 1.7 1 1 0 1 1 1 1 TIP49 C-terminus AAA_26 PF13500.1 CBK25276.2 - 0.0022 17.6 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CBK25276.2 - 0.0023 17.6 0.0 0.4 10.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 CBK25276.2 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBK25276.2 - 0.0024 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK25276.2 - 0.0032 16.4 0.5 0.0079 15.1 0.1 1.7 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 CBK25276.2 - 0.0078 16.1 0.1 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CBK25276.2 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CBK25276.2 - 0.01 15.4 0.0 0.025 14.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CBK25276.2 - 0.012 14.4 0.1 0.03 13.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CBK25276.2 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 CBK25276.2 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBK25276.2 - 0.018 14.1 0.3 0.052 12.6 0.2 1.8 1 1 0 1 1 1 0 Zeta toxin SKI PF01202.17 CBK25276.2 - 0.019 14.8 0.7 0.054 13.3 0.0 2.1 3 0 0 3 3 1 0 Shikimate kinase Sigma54_activat PF00158.21 CBK25276.2 - 0.025 14.0 0.1 0.091 12.2 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 CBK25276.2 - 0.027 14.0 0.1 0.069 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBK25276.2 - 0.029 14.2 0.0 0.085 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CBK25276.2 - 0.042 13.0 0.2 0.092 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 CBK25276.2 - 0.062 12.9 0.1 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CBK25276.2 - 0.11 12.7 0.1 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MFS_1 PF07690.11 CBK25277.2 - 1e-18 67.1 0.0 1.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBK25277.2 - 8.4e-16 57.5 0.0 1.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CBK25277.2 - 8.8e-05 20.8 0.1 0.0001 20.6 0.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CBK25277.2 - 0.0038 15.6 2.3 0.014 13.7 0.3 2.2 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 CBK25277.2 - 0.057 13.2 0.3 0.78 9.5 0.0 2.5 1 1 1 2 2 2 0 MFS_1 like family zf-RNPHF PF08080.7 CBK25277.2 - 0.088 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 RNPHF zinc finger OATP PF03137.15 CBK25277.2 - 0.092 10.7 1.0 6.3 4.7 0.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SET PF00856.23 CBK25278.2 - 4.3e-29 101.8 0.2 2e-28 99.7 0.2 1.9 1 1 0 1 1 1 1 SET domain Amidohydro_4 PF13147.1 CBK25280.2 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CBK25280.2 - 0.036 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase ComA PF02679.10 CBK25280.2 - 0.056 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) He_PIG PF05345.7 CBK25281.2 - 4.6e-05 23.3 0.1 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Putative Ig domain Protocadherin PF08374.6 CBK25281.2 - 0.00012 21.7 1.8 0.00034 20.3 1.2 1.6 2 0 0 2 2 2 1 Protocadherin TMEM154 PF15102.1 CBK25281.2 - 0.0073 16.0 0.1 0.0097 15.6 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 CBK25281.2 - 0.0091 16.3 2.1 0.015 15.6 1.5 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain HemY_N PF07219.8 CBK25281.2 - 0.013 15.0 1.0 0.021 14.3 0.7 1.3 1 0 0 1 1 1 0 HemY protein N-terminus P12 PF12669.2 CBK25281.2 - 0.013 15.6 1.0 0.03 14.5 0.7 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family ASFV_J13L PF05568.6 CBK25281.2 - 0.047 13.2 1.0 0.074 12.5 0.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Shisa PF13908.1 CBK25281.2 - 0.047 13.8 1.1 0.076 13.1 0.8 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RCR PF12273.3 CBK25281.2 - 0.06 13.9 0.2 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF3609 PF12259.3 CBK25281.2 - 0.088 11.4 0.3 0.26 9.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) DUF4389 PF14333.1 CBK25281.2 - 0.088 12.5 1.6 0.15 11.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF1510 PF07423.6 CBK25281.2 - 0.099 11.9 1.5 0.14 11.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) OSTbeta PF15048.1 CBK25281.2 - 0.19 11.8 1.0 0.29 11.2 0.7 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein OAD_gamma PF04277.8 CBK25281.2 - 8.5 6.8 8.1 21 5.5 5.6 1.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SET PF00856.23 CBK25282.2 - 2.9e-07 30.9 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 2 SET domain Yip1 PF04893.12 CBK25283.2 - 8.8e-07 28.5 7.8 3.8e-06 26.5 5.4 1.9 1 1 0 1 1 1 1 Yip1 domain GCV_T PF01571.16 CBK25284.2 - 6.1e-63 211.9 0.0 8.2e-63 211.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBK25284.2 - 3.9e-25 87.7 0.5 9.2e-25 86.5 0.4 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBK25284.2 - 0.055 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family FtsJ PF01728.14 CBK25285.2 - 4e-56 189.8 0.3 1.1e-55 188.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spb1_C PF07780.7 CBK25285.2 - 2.4e-42 144.8 21.5 2.4e-42 144.8 14.9 4.6 3 3 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 CBK25285.2 - 2.1e-32 111.8 10.8 2.1e-32 111.8 7.5 5.0 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) Collagen PF01391.13 CBK25285.2 - 1.5 8.4 9.2 0.45 10.1 1.5 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Ribosomal_L40e PF01020.12 CBK25286.2 - 1.2e-31 107.9 13.7 1.7e-31 107.5 9.5 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBK25286.2 - 6e-21 73.6 0.3 8.2e-21 73.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBK25286.2 - 3.8e-12 45.7 0.7 4.7e-12 45.4 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CBK25286.2 - 0.00025 20.8 0.1 0.00048 19.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBK25286.2 - 0.013 15.7 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HTH_15 PF12324.3 CBK25286.2 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase CK_II_beta PF01214.13 CBK25287.2 - 2.8e-70 235.5 1.7 4.1e-70 235.0 1.2 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CH PF00307.26 CBK25288.2 - 2.4e-06 27.5 0.2 5.3e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain Med4 PF10018.4 CBK25288.2 - 0.0094 15.3 1.4 0.02 14.2 1.0 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CAMSAP_CH PF11971.3 CBK25288.2 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Cortex-I_coil PF09304.5 CBK25288.2 - 0.014 15.4 1.1 0.034 14.1 0.8 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil GAS PF13851.1 CBK25288.2 - 0.021 14.0 0.4 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 CBK25288.2 - 0.023 13.3 0.7 0.046 12.3 0.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 CBK25288.2 - 0.039 13.5 1.2 0.044 13.3 0.2 1.6 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 CBK25288.2 - 0.085 10.6 0.3 0.1 10.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 CBK25288.2 - 0.24 11.2 4.2 0.1 12.4 0.6 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CBK25288.2 - 0.5 10.1 4.4 0.36 10.6 1.5 1.7 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) tRNA_edit PF04073.10 CBK25289.2 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain LRR_8 PF13855.1 CBK25291.2 - 0.01 15.5 1.3 6.4 6.6 0.0 2.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 CBK25291.2 - 0.016 14.8 0.2 2.6 7.7 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) hSac2 PF12456.3 CBK25291.2 - 0.021 14.2 0.7 1.4 8.2 0.0 3.0 1 1 2 3 3 3 0 Inositol phosphatase MORN_2 PF07661.8 CBK25291.2 - 0.43 10.7 10.8 8.1 6.8 0.5 4.5 4 0 0 4 4 4 0 MORN repeat variant AhpC-TSA PF00578.16 CBK25292.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK25292.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK25292.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.27 CBK25293.2 - 7e-25 85.9 3.8 1.7e-09 37.1 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat IKI3 PF04762.7 CBK25293.2 - 0.00091 17.1 0.4 0.001 16.9 0.2 1.0 1 0 0 1 1 1 1 IKI3 family Nbas_N PF15492.1 CBK25293.2 - 0.011 14.8 0.2 7.2 5.6 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 CBK25293.2 - 0.011 15.4 0.3 4.9 6.8 0.0 2.4 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBK25293.2 - 0.053 13.2 0.3 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_hydro_31 PF01055.21 CBK25294.2 - 5.9e-130 434.0 2.6 8.5e-130 433.5 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBK25294.2 - 1.6e-16 59.9 0.1 8.5e-16 57.5 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Ist1 PF03398.9 CBK25296.2 - 1.3e-08 34.3 3.9 2.9e-08 33.3 2.7 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway UPF0051 PF01458.12 CBK25297.2 - 1.3e-30 106.5 0.0 2.6e-30 105.5 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.22 CBK25298.2 - 9.8e-22 77.7 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBK25298.2 - 8.9e-11 42.2 3.1 4.1e-09 36.8 0.4 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 CBK25298.2 - 5.9e-05 22.3 0.1 0.00018 20.7 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBK25298.2 - 7e-05 22.2 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBK25298.2 - 0.00048 19.3 0.1 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBK25298.2 - 0.0037 17.6 1.4 0.0048 17.2 1.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBK25298.2 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 CBK25298.2 - 0.016 13.0 0.2 0.02 12.6 0.1 1.1 1 0 0 1 1 1 0 Helicase AAA_10 PF12846.2 CBK25298.2 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CBK25298.2 - 0.02 14.5 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase MutS_V PF00488.16 CBK25298.2 - 0.023 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 MutS domain V AAA_25 PF13481.1 CBK25298.2 - 0.05 12.9 0.1 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CBK25298.2 - 0.068 11.6 0.2 0.093 11.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBK25298.2 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBK25298.2 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CBK25298.2 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNARE PF05739.14 CBK25299.2 - 2.9e-20 71.6 5.5 4.4e-20 71.1 3.8 1.3 1 0 0 1 1 1 1 SNARE domain DUF2570 PF10828.3 CBK25299.2 - 0.0097 15.4 8.4 0.0097 15.4 5.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2570) RmuC PF02646.11 CBK25299.2 - 0.011 14.5 1.7 0.015 14.1 1.2 1.1 1 0 0 1 1 1 0 RmuC family Tweety PF04906.8 CBK25299.2 - 0.014 13.8 0.1 0.016 13.6 0.1 1.0 1 0 0 1 1 1 0 Tweety Ribosomal_L3 PF00297.17 CBK25299.2 - 0.068 12.5 1.5 0.08 12.3 1.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 DUF4284 PF14112.1 CBK25299.2 - 0.092 13.2 0.3 0.15 12.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4284) Filament PF00038.16 CBK25299.2 - 0.12 11.8 5.6 0.14 11.6 3.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein DcuC PF03606.10 CBK25299.2 - 0.13 10.4 0.4 0.79 7.8 0.1 1.8 1 1 1 2 2 2 0 C4-dicarboxylate anaerobic carrier OmpH PF03938.9 CBK25299.2 - 0.16 11.9 7.4 0.2 11.5 5.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HisKA PF00512.20 CBK25299.2 - 0.24 11.4 1.6 0.38 10.7 0.7 1.7 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain H-kinase_dim PF02895.9 CBK25299.2 - 0.45 10.8 4.7 2.1 8.7 2.1 2.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RGS-like PF09128.6 CBK25299.2 - 0.86 9.0 3.9 1.5 8.2 2.7 1.5 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain DUF106 PF01956.11 CBK25299.2 - 1 8.8 4.0 1.7 8.1 2.8 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 SlyX PF04102.7 CBK25299.2 - 4 7.8 7.1 1.5 9.2 2.2 2.2 2 1 1 3 3 3 0 SlyX Laminin_EGF PF00053.19 CBK25301.2 - 1.5e-05 24.8 87.7 0.26 11.2 6.2 7.1 3 1 3 6 6 6 4 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CBK25301.2 - 7.4e-05 22.8 24.8 0.00017 21.6 7.4 8.5 6 3 2 8 8 8 4 EGF-like domain hEGF PF12661.2 CBK25301.2 - 0.00098 19.0 51.0 0.56 10.4 0.8 9.5 10 0 0 10 10 10 5 Human growth factor-like EGF EGF PF00008.22 CBK25301.2 - 0.028 14.4 9.1 0.028 14.4 6.3 6.7 6 1 0 6 6 6 0 EGF-like domain ODV-E18 PF10717.4 CBK25301.2 - 0.049 13.0 0.5 0.098 12.1 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Pkinase PF00069.20 CBK25302.2 - 5.1e-17 61.8 0.0 7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25302.2 - 4e-11 42.4 0.0 4.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK25302.2 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBK25302.2 - 0.0082 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBK25302.2 - 0.045 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLASP_N PF12348.3 CBK25303.2 - 1.4e-08 34.4 0.1 1.6e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 CLASP N terminal G-gamma PF00631.17 CBK25303.2 - 0.71 9.6 2.6 23 4.8 0.3 2.9 2 1 1 3 3 3 0 GGL domain Pectate_lyase_3 PF12708.2 CBK25305.2 - 1.8e-06 28.2 4.4 4e-06 27.1 3.1 1.6 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF605 PF04652.11 CBK25307.2 - 0.42 9.9 25.9 0.5 9.7 18.0 1.0 1 0 0 1 1 1 0 Vta1 like Aminotran_1_2 PF00155.16 CBK25308.2 - 6.1e-39 133.9 0.0 7.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S4e PF00900.15 CBK25309.2 - 1.1e-28 98.6 0.7 2.6e-28 97.4 0.5 1.6 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.24 CBK25309.2 - 0.0004 19.9 2.0 0.0004 19.9 1.4 3.4 4 0 0 4 4 4 1 KOW motif S4 PF01479.20 CBK25309.2 - 0.012 15.0 0.3 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 S4 domain Clp1 PF06807.9 CBK25310.2 - 3.4e-12 46.5 0.0 4.3e-11 42.9 0.0 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CBK25310.2 - 1.2e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CBK25310.2 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CBK25310.2 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.14 CBK25310.2 - 0.18 11.0 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain Sec1 PF00995.18 CBK25311.2 - 1.1e-50 172.8 0.0 1.4e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family NRN1 PF15056.1 CBK25311.2 - 0.064 13.2 0.0 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 Neuritin protein family Sec1 PF00995.18 CBK25312.2 - 1.3e-13 50.5 0.0 1.3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AhpC-TSA PF00578.16 CBK25313.2 - 1e-35 122.1 0.0 1.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBK25313.2 - 1.2e-13 50.8 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBK25313.2 - 2.3e-11 43.1 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Adeno_E4_ORF3 PF06931.6 CBK25315.2 - 0.11 12.6 0.5 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Mastadenovirus E4 ORF3 protein Collagen PF01391.13 CBK25315.2 - 0.12 11.9 4.1 0.18 11.3 2.8 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) TraL PF07178.6 CBK25315.2 - 8.6 6.4 6.8 2.3 8.2 0.2 3.1 4 0 0 4 4 4 0 TraL protein Lipase_3 PF01764.20 CBK25317.2 - 6e-10 38.8 0.1 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) PPR PF01535.15 CBK25317.2 - 8.5e-05 22.2 1.5 2.9 8.0 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PGAP1 PF07819.8 CBK25317.2 - 0.016 14.8 0.1 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein PPR_2 PF13041.1 CBK25317.2 - 0.018 15.0 5.3 1.8 8.6 0.0 4.5 4 1 1 5 5 5 0 PPR repeat family Abhydrolase_5 PF12695.2 CBK25317.2 - 0.02 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PPR_3 PF13812.1 CBK25317.2 - 0.11 12.8 0.1 39 4.8 0.0 3.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain BTAD PF03704.12 CBK25317.2 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Abhydrolase_6 PF12697.2 CBK25317.2 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fer2 PF00111.22 CBK25318.2 - 3.3e-13 49.1 2.7 4.4e-13 48.7 1.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 CBK25318.2 - 0.012 15.3 1.2 0.041 13.7 0.9 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain UNC-93 PF05978.11 CBK25319.2 - 3.9e-09 36.1 6.1 3.9e-09 36.1 4.2 2.0 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 ABC_cobalt PF09819.4 CBK25319.2 - 0.31 10.9 7.4 0.18 11.7 3.7 1.6 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component Paf1 PF03985.8 CBK25320.2 - 4.1e-06 25.8 0.0 2.1e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Paf1 Cpn60_TCP1 PF00118.19 CBK25321.2 - 2.3e-129 432.2 13.2 2.6e-129 432.0 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 CBK25321.2 - 0.2 11.3 1.6 0.51 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Trypan_PARP PF05887.6 CBK25322.2 - 0.0051 16.6 45.3 0.0051 16.6 31.4 4.2 2 2 2 4 4 4 1 Procyclic acidic repetitive protein (PARP) PP-binding PF00550.20 CBK25323.2 - 1.6e-10 41.0 0.3 1.7e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CBK25323.2 - 0.00065 19.6 0.4 0.00074 19.4 0.3 1.1 1 0 0 1 1 1 1 Acyl-carrier TAF PF02969.12 CBK25323.2 - 0.033 14.1 0.1 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Guanylate_cyc PF00211.15 CBK25323.2 - 0.042 13.1 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Glu-tRNAGln PF02686.10 CBK25323.2 - 0.11 12.3 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit SMC_N PF02463.14 CBK25324.2 - 1.1e-67 227.5 0.0 1.7e-67 226.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBK25324.2 - 8.6e-26 90.2 0.1 2.2e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBK25324.2 - 9.8e-16 58.5 1.1 4.9e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBK25324.2 - 1.5e-15 58.0 5.2 1.5e-15 58.0 3.6 5.8 3 3 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CBK25324.2 - 1.7e-05 24.2 0.0 3.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBK25324.2 - 4.8e-05 22.5 4.0 4.8e-05 22.5 2.8 2.1 2 1 1 3 3 3 1 AAA ATPase domain GAS PF13851.1 CBK25324.2 - 0.00073 18.7 1.3 0.00073 18.7 0.9 6.6 4 2 2 6 6 5 1 Growth-arrest specific micro-tubule binding FUSC PF04632.7 CBK25324.2 - 0.0021 16.6 2.3 0.0021 16.6 1.6 3.8 2 1 1 3 3 1 1 Fusaric acid resistance protein family TPR_8 PF13181.1 CBK25324.2 - 0.013 15.2 1.6 14 5.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 CBK25324.2 - 0.024 13.8 12.3 0.54 9.3 0.5 4.0 3 2 0 3 3 3 0 Reovirus sigma C capsid protein YqjK PF13997.1 CBK25324.2 - 0.062 13.4 3.0 5.2 7.3 0.2 3.7 3 0 0 3 3 3 0 YqjK-like protein ABC_tran PF00005.22 CBK25324.2 - 0.097 12.9 22.9 0.24 11.6 2.1 5.2 3 2 0 3 3 3 0 ABC transporter Mito_fiss_reg PF05308.6 CBK25325.2 - 0.96 8.7 5.2 1.2 8.4 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DNA_pol_B_2 PF03175.8 CBK25326.2 - 5.5e-08 31.9 7.5 0.0012 17.5 0.2 3.4 2 1 0 3 3 3 3 DNA polymerase type B, organellar and viral Ribosomal_L3 PF00297.17 CBK25327.2 - 1.8e-114 381.5 8.0 2.2e-114 381.3 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 La PF05383.12 CBK25328.2 - 8.1e-21 73.5 0.4 1.9e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CBK25328.2 - 1.2e-05 25.2 1.0 6.9e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK25328.2 - 9.5e-05 21.9 0.1 0.00031 20.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK25328.2 - 0.19 11.5 0.6 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC27 PF09507.5 CBK25328.2 - 1.1 8.4 20.8 1.8 7.7 14.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ldh_1_N PF00056.18 CBK25329.2 - 2.1e-43 147.5 0.0 3e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBK25329.2 - 2.5e-37 128.2 0.0 3.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CBK25329.2 - 0.0031 16.2 0.0 0.0043 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CBK25329.2 - 0.063 13.5 0.0 1.1 9.6 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBK25329.2 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding TPR_14 PF13428.1 CBK25330.2 - 2.3e-10 40.1 12.9 0.027 15.0 0.0 6.7 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBK25330.2 - 1.6e-09 37.9 13.8 0.08 13.3 0.1 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBK25330.2 - 5e-07 30.2 9.0 0.13 12.9 0.1 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBK25330.2 - 7.9e-06 25.4 14.0 0.26 10.9 0.0 5.6 6 1 2 8 8 8 3 TPR repeat TPR_15 PF13429.1 CBK25330.2 - 0.00082 18.5 8.6 0.0075 15.3 0.1 2.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBK25330.2 - 0.0015 18.2 13.3 2.5 8.2 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.5 CBK25330.2 - 0.0049 15.6 0.8 0.15 10.8 0.0 2.4 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 CBK25330.2 - 0.014 15.3 11.0 1.3 9.0 0.0 4.6 4 2 1 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBK25330.2 - 0.023 14.8 5.2 0.65 10.1 0.0 3.8 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.9 CBK25330.2 - 0.025 14.3 0.0 0.025 14.3 0.0 2.4 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_8 PF13181.1 CBK25330.2 - 0.03 14.0 13.5 5.7 6.9 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25330.2 - 0.034 14.3 1.5 15 6.1 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CBK25330.2 - 0.065 13.0 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 TPR_1 PF00515.23 CBK25330.2 - 0.083 12.5 3.8 26 4.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBK25330.2 - 0.12 11.5 2.3 0.36 9.9 0.1 2.6 2 1 0 2 2 2 0 Coatomer epsilon subunit Nucleoplasmin PF03066.10 CBK25330.2 - 0.28 10.6 3.6 0.48 9.9 2.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CBK25330.2 - 0.57 10.5 5.9 1.1 9.6 4.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CBK25330.2 - 2.3 8.4 7.8 5.5 7.2 5.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.20 CBK25332.2 - 1.5e-53 181.5 0.0 2.7e-52 177.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25332.2 - 3.1e-28 98.5 0.0 4.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK25332.2 - 2.9e-05 23.9 0.0 0.0068 16.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBK25332.2 - 5.3e-05 22.3 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBK25332.2 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBK25332.2 - 0.0039 16.5 0.1 0.021 14.1 0.0 2.2 3 0 0 3 3 3 1 RIO1 family Choline_kinase PF01633.15 CBK25332.2 - 0.059 12.9 0.1 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase dDENN PF03455.14 CBK25334.2 - 1.6e-05 24.8 0.4 1.6e-05 24.8 0.3 2.2 3 0 0 3 3 3 1 dDENN domain DUF2508 PF10704.4 CBK25334.2 - 0.38 10.9 2.5 11 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DENN PF02141.16 CBK25335.2 - 9.2e-39 133.0 2.8 4.2e-38 130.9 1.9 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 CBK25335.2 - 0.00017 21.2 0.1 0.0004 20.0 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis UCH PF00443.24 CBK25336.2 - 6.4e-16 58.2 1.0 8.4e-16 57.8 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK25336.2 - 3.4e-07 30.0 0.4 5.2e-07 29.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2955 PF11168.3 CBK25336.2 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) WD40 PF00400.27 CBK25337.2 - 2.8e-10 39.6 0.2 0.0096 15.7 0.0 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Pkinase PF00069.20 CBK25338.2 - 3.2e-16 59.2 0.0 1e-15 57.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25338.2 - 0.00044 19.3 0.0 0.49 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBK25338.2 - 0.0022 16.9 0.0 0.0053 15.6 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 CBK25338.2 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family MIF4G PF02854.14 CBK25338.2 - 0.018 14.4 0.9 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 MIF4G domain Kinase-like PF14531.1 CBK25338.2 - 0.021 13.7 0.3 0.077 11.9 0.0 2.0 3 0 0 3 3 3 0 Kinase-like UCH PF00443.24 CBK25339.2 - 6e-17 61.6 0.9 7e-17 61.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK25339.2 - 0.0083 15.6 1.1 0.01 15.2 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 CBK25340.2 - 5.1e-18 65.1 1.3 5.1e-18 65.1 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK25340.2 - 0.045 13.1 1.1 0.057 12.8 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF4661 PF15576.1 CBK25340.2 - 4.1 6.9 6.0 5.2 6.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Aa_trans PF01490.13 CBK25341.2 - 2.4e-16 59.2 16.6 3.1e-16 58.8 11.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Neuromodulin_N PF10580.4 CBK25341.2 - 0.11 12.1 0.8 0.28 10.8 0.6 1.6 1 0 0 1 1 1 0 Gap junction protein N-terminal region CCDC84 PF14968.1 CBK25343.2 - 5.5e-36 124.7 16.6 1.5e-18 67.4 1.7 2.2 2 0 0 2 2 2 2 Coiled coil protein 84 zf-DBF PF07535.7 CBK25343.2 - 4.6 6.9 8.4 0.51 10.0 1.3 2.4 2 0 0 2 2 2 0 DBF zinc finger DUF647 PF04884.9 CBK25344.2 - 7.1e-58 195.7 2.5 9.8e-58 195.2 1.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis WD-3 PF09765.4 CBK25344.2 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 WD-repeat region UNC-93 PF05978.11 CBK25345.2 - 7.8e-13 48.2 10.4 7.8e-13 48.2 7.2 3.4 1 1 3 4 4 4 1 Ion channel regulatory protein UNC-93 LRV_FeS PF05484.6 CBK25345.2 - 0.023 14.2 4.1 0.023 14.2 2.8 1.6 1 1 0 1 1 1 0 LRV protein FeS4 cluster Arf PF00025.16 CBK25346.2 - 2.8e-78 261.1 0.4 3.1e-78 261.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBK25346.2 - 8.5e-15 54.4 0.0 1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBK25346.2 - 2.7e-14 52.8 0.1 3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK25346.2 - 6.6e-13 48.1 1.7 1.2e-09 37.3 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK25346.2 - 3.3e-11 42.7 0.0 4e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK25346.2 - 8.2e-10 39.2 0.1 1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK25346.2 - 2.7e-06 27.3 0.1 3.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK25346.2 - 0.0034 16.8 0.1 0.022 14.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CBK25346.2 - 0.0046 16.0 0.2 0.0075 15.3 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBK25346.2 - 0.039 13.8 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBK25346.2 - 0.046 13.1 0.2 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBK25346.2 - 0.15 12.3 0.3 0.36 11.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBK25346.2 - 0.26 11.1 1.7 6.1 6.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Arf PF00025.16 CBK25347.2 - 2.8e-78 261.1 0.4 3.1e-78 261.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBK25347.2 - 8.5e-15 54.4 0.0 1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBK25347.2 - 2.7e-14 52.8 0.1 3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK25347.2 - 6.6e-13 48.1 1.7 1.2e-09 37.3 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK25347.2 - 3.3e-11 42.7 0.0 4e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK25347.2 - 8.2e-10 39.2 0.1 1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK25347.2 - 2.7e-06 27.3 0.1 3.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK25347.2 - 0.0034 16.8 0.1 0.022 14.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CBK25347.2 - 0.0046 16.0 0.2 0.0075 15.3 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBK25347.2 - 0.039 13.8 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBK25347.2 - 0.046 13.1 0.2 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBK25347.2 - 0.15 12.3 0.3 0.36 11.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBK25347.2 - 0.26 11.1 1.7 6.1 6.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Arf PF00025.16 CBK25348.2 - 2.8e-78 261.1 0.4 3.1e-78 261.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBK25348.2 - 8.5e-15 54.4 0.0 1e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBK25348.2 - 2.7e-14 52.8 0.1 3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBK25348.2 - 6.6e-13 48.1 1.7 1.2e-09 37.3 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBK25348.2 - 3.3e-11 42.7 0.0 4e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBK25348.2 - 8.2e-10 39.2 0.1 1e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBK25348.2 - 2.7e-06 27.3 0.1 3.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBK25348.2 - 0.0034 16.8 0.1 0.022 14.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CBK25348.2 - 0.0046 16.0 0.2 0.0075 15.3 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBK25348.2 - 0.039 13.8 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBK25348.2 - 0.046 13.1 0.2 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBK25348.2 - 0.15 12.3 0.3 0.36 11.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBK25348.2 - 0.26 11.1 1.7 6.1 6.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Sec5 PF15469.1 CBK25349.2 - 3e-24 85.7 2.1 3e-24 85.7 1.4 2.0 1 1 1 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 CBK25349.2 - 4.8e-20 71.1 2.0 4.8e-20 71.1 1.4 2.5 3 0 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.7 CBK25349.2 - 1.2e-10 40.3 6.0 2.4e-10 39.4 3.8 1.7 1 1 1 2 2 2 1 Dor1-like family DUF2450 PF10475.4 CBK25349.2 - 2.1e-10 39.9 6.8 2.7e-10 39.6 3.8 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CBK25349.2 - 1.1e-06 28.5 10.6 3.5e-06 26.9 2.0 2.4 2 1 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.7 CBK25349.2 - 0.0017 17.1 3.9 0.0024 16.7 2.7 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal COG5 PF10392.4 CBK25349.2 - 0.0032 17.4 6.5 0.0068 16.3 1.3 2.6 2 1 0 2 2 2 1 Golgi transport complex subunit 5 FadA PF09403.5 CBK25349.2 - 0.0093 15.9 0.1 0.0093 15.9 0.1 2.4 3 0 0 3 3 3 1 Adhesion protein FadA ING PF12998.2 CBK25349.2 - 0.064 13.5 5.6 0.94 9.7 0.2 3.5 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF717 PF05338.7 CBK25349.2 - 0.098 12.6 0.4 0.79 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF717) CENP-F_leu_zip PF10473.4 CBK25349.2 - 0.12 12.2 3.1 0.12 12.2 0.2 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.6 CBK25349.2 - 0.19 10.8 5.4 0.028 13.5 1.2 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Sec8_exocyst PF04048.9 CBK25349.2 - 0.25 10.9 3.9 0.19 11.3 0.4 2.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain He_PIG PF05345.7 CBK25352.2 - 3.1e-09 36.7 3.4 0.0004 20.3 0.0 3.8 4 0 0 4 4 4 2 Putative Ig domain ODV-E18 PF10717.4 CBK25352.2 - 0.01 15.2 1.0 0.01 15.2 0.7 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_11_kDa PF06143.6 CBK25352.2 - 1.1 8.7 6.1 2.6 7.4 4.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family ASFV_J13L PF05568.6 CBK25352.2 - 3 7.3 4.9 8.3 5.8 3.1 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF1514 PF07438.6 CBK25352.2 - 3.2 7.7 5.4 1.3 8.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) GCK PF07802.6 CBK25353.2 - 5.7e-07 29.5 12.4 0.00083 19.4 0.1 3.0 2 1 1 3 3 3 2 GCK domain Ph1570 PF09638.5 CBK25353.2 - 2.2 8.0 5.2 1.4 8.7 0.5 2.3 2 0 0 2 2 2 0 Ph1570 protein PP2C PF00481.16 CBK25354.2 - 1.6e-36 126.0 0.0 6.9e-36 123.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBK25354.2 - 3.8e-05 23.1 0.0 0.00024 20.5 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C DAOA PF15199.1 CBK25354.2 - 0.092 13.3 0.0 6.6 7.4 0.0 2.5 2 0 0 2 2 2 0 D-amino acid oxidase activator Y_phosphatase2 PF03162.8 CBK25355.2 - 8.7e-55 184.5 0.0 1.2e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CBK25355.2 - 3.2e-07 30.7 0.0 1.1e-06 28.9 0.0 1.7 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CBK25355.2 - 0.0084 15.6 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBK25355.2 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ubiquitin PF00240.18 CBK25356.2 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family UCH PF00443.24 CBK25357.2 - 3.8e-14 52.4 0.0 2.1e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBK25357.2 - 6.6e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-FCS PF06467.9 CBK25357.2 - 0.94 9.1 7.9 8 6.1 5.5 2.3 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pkinase PF00069.20 CBK25358.2 - 3.1e-21 75.6 0.0 3.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25358.2 - 3.2e-12 46.0 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBK25358.2 - 0.023 13.6 0.0 0.05 12.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like PTH2 PF01981.11 CBK25359.2 - 1.2e-41 141.0 0.0 1.2e-41 141.0 0.0 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.1 CBK25359.2 - 0.041 13.5 0.1 0.041 13.5 0.1 1.6 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.8 CBK25359.2 - 1 7.0 8.2 1.4 6.6 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 CBK25359.2 - 1.4 8.4 6.5 2.1 7.8 4.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin V_ATPase_I PF01496.14 CBK25360.2 - 7.5e-206 685.4 7.0 8.5e-206 685.2 4.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3641 PF12345.3 CBK25360.2 - 1.7 8.4 4.6 2.9 7.7 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3641) PLAT PF01477.18 CBK25361.2 - 1.4e-15 57.6 0.0 3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.7 CBK25361.2 - 8.5e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBK25361.2 - 0.065 12.6 0.2 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein phosphatase 2C NUC173 PF08161.7 CBK25362.2 - 2e-14 53.4 0.4 1.1e-13 50.9 0.1 2.3 2 0 0 2 2 2 1 NUC173 domain DUF2435 PF10363.4 CBK25362.2 - 0.35 10.7 3.7 0.34 10.8 0.2 2.9 3 2 0 3 3 3 0 Protein of unknown function (DUF2435) CLASP_N PF12348.3 CBK25363.2 - 0.013 14.9 1.0 1.1 8.5 0.0 2.6 2 1 1 3 3 3 0 CLASP N terminal HEAT PF02985.17 CBK25363.2 - 0.021 14.8 1.5 1.6 9.0 0.1 4.3 5 0 0 5 5 5 0 HEAT repeat ParcG PF10274.4 CBK25363.2 - 0.061 13.2 0.3 3.3 7.5 0.1 2.3 1 1 0 2 2 2 0 Parkin co-regulated protein DNA_pol_A_exo1 PF01612.15 CBK25364.2 - 1.1e-17 64.0 0.1 1.7e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Kinesin PF00225.18 CBK25364.2 - 1.4e-07 30.5 0.0 2.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 CBK25365.2 - 7.9e-15 54.3 0.5 1.9e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain CCDC155 PF14662.1 CBK25365.2 - 0.00042 19.9 8.1 0.00059 19.4 5.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 IncA PF04156.9 CBK25365.2 - 0.0005 19.7 1.8 0.0006 19.4 1.2 1.2 1 0 0 1 1 1 1 IncA protein Troponin PF00992.15 CBK25365.2 - 0.0019 18.2 6.1 0.0027 17.7 4.2 1.2 1 0 0 1 1 1 1 Troponin bZIP_1 PF00170.16 CBK25365.2 - 0.0023 17.8 3.7 0.0055 16.6 2.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 CBK25365.2 - 0.0058 16.8 8.4 0.017 15.4 5.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 CBK25365.2 - 0.011 15.4 8.6 0.016 14.9 6.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 CBK25365.2 - 0.012 15.1 3.1 0.02 14.3 2.1 1.5 1 1 0 1 1 1 0 Septum formation initiator HAUS-augmin3 PF14932.1 CBK25365.2 - 0.012 14.8 1.9 0.017 14.2 1.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HALZ PF02183.13 CBK25365.2 - 0.014 15.0 4.4 0.032 13.9 3.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1202 PF06717.6 CBK25365.2 - 0.021 14.1 0.1 0.029 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) TMF_DNA_bd PF12329.3 CBK25365.2 - 0.023 14.5 5.7 0.036 13.8 3.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CBK25365.2 - 0.033 14.5 4.9 0.064 13.6 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Vps53_N PF04100.7 CBK25365.2 - 0.036 12.8 3.3 0.048 12.4 2.3 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal TBPIP PF07106.8 CBK25365.2 - 0.06 12.8 3.9 0.08 12.4 2.7 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 CBK25365.2 - 0.06 13.0 4.0 0.079 12.6 2.1 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Baculo_PEP_C PF04513.7 CBK25365.2 - 0.061 13.1 0.8 0.095 12.5 0.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2968 PF11180.3 CBK25365.2 - 0.063 12.6 2.6 0.078 12.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4140 PF13600.1 CBK25365.2 - 0.068 13.6 0.7 0.14 12.6 0.5 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Prominin PF05478.6 CBK25365.2 - 0.07 10.6 2.5 0.096 10.2 1.7 1.2 1 0 0 1 1 1 0 Prominin ADIP PF11559.3 CBK25365.2 - 0.072 12.9 6.0 0.11 12.4 4.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 CBK25365.2 - 0.082 12.7 0.9 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EMP24_GP25L PF01105.19 CBK25365.2 - 0.082 12.6 2.1 0.12 12.0 1.5 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Med4 PF10018.4 CBK25365.2 - 0.087 12.2 4.7 0.16 11.3 3.3 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin_2 PF14523.1 CBK25365.2 - 0.088 12.8 1.4 0.17 11.8 1.0 1.5 1 0 0 1 1 1 0 Syntaxin-like protein NPV_P10 PF05531.7 CBK25365.2 - 0.1 12.8 0.7 0.21 11.8 0.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 CBK25365.2 - 0.11 11.3 3.5 0.15 10.9 2.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DIL PF01843.14 CBK25365.2 - 0.12 12.2 0.3 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 DIL domain DUF956 PF06115.6 CBK25365.2 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) V_ATPase_I PF01496.14 CBK25365.2 - 0.16 9.8 5.0 0.2 9.4 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tnp_P_element PF12017.3 CBK25365.2 - 0.16 11.1 1.4 0.25 10.5 1.0 1.3 1 0 0 1 1 1 0 Transposase protein APG6 PF04111.7 CBK25365.2 - 0.17 10.8 6.7 0.24 10.4 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF87 PF01935.12 CBK25365.2 - 0.19 11.5 1.5 0.28 10.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF3552 PF12072.3 CBK25365.2 - 0.22 10.7 9.9 0.29 10.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.7 CBK25365.2 - 0.31 10.8 2.2 0.48 10.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 CBK25365.2 - 0.58 10.6 5.8 1.7 9.0 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) bZIP_2 PF07716.10 CBK25365.2 - 0.62 9.9 5.9 0.73 9.7 3.3 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Reo_sigmaC PF04582.7 CBK25365.2 - 2 7.5 4.5 0.77 8.8 0.5 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 CBK25365.2 - 4.3 7.3 15.3 0.53 10.2 2.0 3.4 3 1 1 4 4 2 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 CBK25365.2 - 5.5 6.9 7.3 9 6.2 0.4 2.6 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 CBK25366.2 - 0.011 15.4 2.4 0.011 15.4 1.7 6.5 8 0 0 8 8 8 0 Protein of unknown function (DUF1192) FlxA PF14282.1 CBK25366.2 - 0.016 15.1 9.2 0.016 15.1 6.4 7.7 3 1 5 8 8 8 0 FlxA-like protein Lip_prot_lig_C PF10437.4 CBK25366.2 - 0.15 11.7 5.1 1.1 8.9 0.2 3.8 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Matrilin_ccoil PF10393.4 CBK25366.2 - 0.43 9.9 15.0 0.4 10.0 0.5 4.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4497 PF14924.1 CBK25366.2 - 1.2 9.4 10.3 0.45 10.8 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4497) AAA_13 PF13166.1 CBK25366.2 - 2.5 6.4 77.5 0.81 8.0 15.9 3.3 1 1 2 3 3 3 0 AAA domain AAA_27 PF13514.1 CBK25366.2 - 3.1 5.3 86.6 0.14 9.8 45.1 2.3 1 1 1 2 2 2 0 AAA domain EMP70 PF02990.11 CBK25367.2 - 4.2e-139 464.3 16.4 4.2e-139 464.3 11.4 1.6 1 1 0 1 1 1 1 Endomembrane protein 70 Pro_isomerase PF00160.16 CBK25367.2 - 5.2e-29 101.4 0.0 8.3e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HPS3_C PF14763.1 CBK25368.2 - 0.14 11.1 0.5 0.16 10.9 0.4 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal DUF1441 PF07278.6 CBK25368.2 - 0.14 11.7 0.8 0.18 11.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) Actin PF00022.14 CBK25369.2 - 5.4e-17 61.2 0.0 6e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 CBK25370.2 - 5.8e-21 74.3 0.0 6.9e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Actin HEAT PF02985.17 CBK25371.2 - 1.9e-14 52.3 2.3 0.0087 16.0 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 CBK25371.2 - 3.9e-07 30.2 3.3 0.11 12.7 0.0 3.7 2 1 1 3 3 3 3 HEAT repeats Adaptin_N PF01602.15 CBK25371.2 - 5.2e-07 28.3 0.7 0.0032 15.8 0.1 2.5 2 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CBK25371.2 - 0.00011 22.5 0.4 0.048 14.0 0.0 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBK25371.2 - 0.0018 18.6 1.0 1.8 9.1 0.1 3.7 3 0 0 3 3 3 1 HEAT-like repeat CLASP_N PF12348.3 CBK25371.2 - 0.0083 15.4 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.2 CBK25371.2 - 0.049 13.4 0.4 8.3 6.2 0.0 3.3 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 CBK25371.2 - 0.19 11.6 1.4 1.4 8.9 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion MAD PF05557.8 CBK25372.2 - 4.3e-29 101.1 21.4 1.4e-25 89.5 0.2 3.0 1 1 2 3 3 3 3 Mitotic checkpoint protein YgaB PF14182.1 CBK25372.2 - 0.009 16.2 13.3 0.3 11.3 0.0 4.0 2 1 2 4 4 4 2 YgaB-like protein DUF3763 PF12592.3 CBK25372.2 - 1.2 8.7 6.8 17 5.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3763) TAF1D PF15333.1 CBK25372.2 - 1.3 8.8 8.1 0.39 10.4 3.0 1.8 1 1 1 2 2 2 0 TATA box-binding protein-associated factor 1D Clat_adaptor_s PF01217.15 CBK25373.2 - 2.8e-28 98.4 0.4 3.4e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nuc_sug_transp PF04142.10 CBK25374.2 - 9.2e-67 224.6 12.9 1e-66 224.5 9.0 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CBK25374.2 - 2.4e-09 37.4 4.6 2.4e-09 37.4 3.2 2.9 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 CBK25374.2 - 1.3e-08 34.6 15.7 6.5e-06 25.8 2.7 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBK25374.2 - 3.2e-08 33.6 6.3 3.2e-08 33.6 4.4 2.8 2 1 1 3 3 3 1 EamA-like transporter family UAA PF08449.6 CBK25374.2 - 2.2e-06 26.8 11.0 3e-06 26.3 7.7 1.2 1 0 0 1 1 1 1 UAA transporter family DUF1129 PF06570.6 CBK25374.2 - 0.0079 15.5 0.7 0.019 14.3 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1129) Sugar_transport PF06800.7 CBK25374.2 - 0.013 14.5 5.8 0.03 13.4 3.6 1.7 1 1 0 1 1 1 0 Sugar transport protein Multi_Drug_Res PF00893.14 CBK25374.2 - 1.2 9.6 12.8 0.15 12.5 3.4 2.8 2 1 0 3 3 3 0 Small Multidrug Resistance protein PrgI PF12666.2 CBK25374.2 - 2.3 8.4 7.5 0.74 9.9 0.6 2.7 2 1 0 2 2 2 0 PrgI family protein CHCH PF06747.8 CBK25375.2 - 5.8e-05 22.8 0.4 8.1e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 CBK25375.2 - 0.081 13.0 2.1 0.45 10.6 0.2 2.2 1 1 1 2 2 2 0 GCK domain XPC-binding PF09280.6 CBK25375.2 - 0.13 11.7 0.1 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 XPC-binding domain LSM PF01423.17 CBK25377.2 - 1.4e-17 62.9 1.1 1.9e-17 62.5 0.8 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 CBK25377.2 - 0.0044 16.6 0.8 0.0081 15.8 0.5 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Fumble PF03630.9 CBK25378.2 - 4.1e-99 331.6 0.1 5e-99 331.3 0.1 1.0 1 0 0 1 1 1 1 Fumble Mob1_phocein PF03637.12 CBK25379.2 - 2.4e-34 118.5 2.2 2.7e-34 118.3 1.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Maf PF02545.9 CBK25380.2 - 1.9e-19 69.5 0.0 2.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein zf-Sec23_Sec24 PF04810.10 CBK25380.2 - 1.7 8.2 5.1 0.58 9.7 1.3 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger VWA_2 PF13519.1 CBK25381.2 - 0.011 15.8 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_19 PF14559.1 CBK25382.2 - 0.00026 21.2 0.0 0.0023 18.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK25382.2 - 0.017 15.7 0.0 1.4 9.7 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.15 CBK25383.2 - 4.7e-69 232.7 0.1 6.8e-69 232.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBK25383.2 - 2.4e-10 40.1 0.2 4.9e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBK25383.2 - 0.00043 19.5 0.4 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) ATP-synt_ab PF00006.20 CBK25384.2 - 7e-109 362.3 0.0 1e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK25384.2 - 4.1e-25 88.4 0.4 8.2e-25 87.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK25384.2 - 8e-13 48.4 2.4 2.6e-12 46.7 0.2 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_17 PF13207.1 CBK25384.2 - 0.032 15.0 0.1 0.53 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBK25384.2 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK25384.2 - 0.085 12.8 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_L24e PF01246.15 CBK25385.2 - 6.7e-23 80.3 1.7 6.7e-23 80.3 1.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Phospholip_A2_1 PF00068.14 CBK25385.2 - 0.03 14.5 0.1 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A2 Ribosomal_L24e PF01246.15 CBK25387.2 - 5.1e-23 80.7 1.7 5.1e-23 80.7 1.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e ATP-synt_ab PF00006.20 CBK25388.2 - 7e-109 362.3 0.0 1e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBK25388.2 - 4.1e-25 88.4 0.4 8.2e-25 87.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBK25388.2 - 8e-13 48.4 2.4 2.6e-12 46.7 0.2 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_17 PF13207.1 CBK25388.2 - 0.032 15.0 0.1 0.53 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBK25388.2 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBK25388.2 - 0.085 12.8 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain SH2 PF00017.19 CBK25389.2 - 0.037 13.8 0.3 0.26 11.1 0.0 2.7 2 1 0 2 2 2 0 SH2 domain DUF3776 PF12618.3 CBK25389.2 - 0.11 13.0 13.6 0.25 11.9 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) DUF3199 PF11436.3 CBK25389.2 - 0.48 10.2 6.9 6 6.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3199) Fer2 PF00111.22 CBK25390.2 - 1e-10 41.1 0.5 1e-10 41.1 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.1 CBK25390.2 - 0.14 11.9 2.4 0.78 9.5 1.7 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TPR_11 PF13414.1 CBK25392.2 - 1.4e-08 34.2 0.1 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBK25392.2 - 5.3e-07 29.0 0.1 0.15 12.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 CBK25392.2 - 7.3e-07 28.9 0.1 2e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 CBK25392.2 - 1.1e-05 25.4 0.8 8.2e-05 22.6 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBK25392.2 - 1.3e-05 25.4 0.1 0.25 12.0 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK25392.2 - 1.6e-05 25.1 0.3 3.5e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBK25392.2 - 4.2e-05 22.9 2.9 3.1 7.5 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBK25392.2 - 0.008 16.0 0.1 1 9.3 0.0 2.8 2 2 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 CBK25392.2 - 0.011 14.4 0.1 0.012 14.3 0.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 CBK25392.2 - 0.012 16.2 0.0 0.035 14.7 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25392.2 - 0.022 14.9 0.1 0.3 11.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBK25392.2 - 0.065 13.0 0.5 17 5.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2373 PF10180.4 CBK25393.2 - 2.4e-20 71.8 2.3 2.4e-20 71.8 1.6 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) DUF1674 PF07896.7 CBK25394.2 - 5.1e-11 42.6 5.9 1.1e-10 41.5 4.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) CoA_binding PF02629.14 CBK25395.2 - 9.4e-29 99.7 1.3 9.4e-29 99.7 0.9 2.6 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBK25395.2 - 1.9e-23 82.7 0.1 3.8e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBK25395.2 - 2.2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK25395.2 - 5.3e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CBK25395.2 - 0.0042 17.6 0.1 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SseB PF07179.7 CBK25395.2 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 SseB protein N-terminal domain Ribosomal_L21e PF01157.13 CBK25396.2 - 2.6e-28 97.7 2.0 4.3e-28 97.0 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Put_Phosphatase PF06888.7 CBK25396.2 - 0.044 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative Phosphatase MSP1b PF03429.8 CBK25396.2 - 0.15 9.9 0.0 0.18 9.6 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B DUF814 PF05670.8 CBK25397.2 - 2.1e-20 72.3 0.0 3.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) ketoacyl-synt PF00109.21 CBK25398.2 - 2e-76 256.8 0.5 9.3e-76 254.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CBK25398.2 - 2.3e-65 221.0 0.1 4.5e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 CBK25398.2 - 8.8e-50 168.8 0.1 1.4e-47 161.7 0.0 2.6 2 0 0 2 2 2 1 KR domain Aminotran_1_2 PF00155.16 CBK25398.2 - 1.2e-47 162.5 0.0 2.4e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II adh_short PF00106.20 CBK25398.2 - 4.6e-41 140.5 0.0 1.7e-37 128.8 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 CBK25398.2 - 1.5e-38 132.6 0.0 2.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CBK25398.2 - 1.6e-35 121.5 0.4 4.1e-35 120.2 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 CBK25398.2 - 1.6e-28 98.8 0.0 1.1e-27 96.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBK25398.2 - 2.1e-11 44.8 0.0 7e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBK25398.2 - 2.5e-08 33.6 0.2 2.5e-08 33.6 0.2 3.0 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 CBK25398.2 - 3.3e-07 30.4 0.3 1e-06 28.8 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ELFV_dehydrog PF00208.16 CBK25398.2 - 6.4e-07 29.1 1.2 0.0045 16.6 0.0 2.7 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Thiolase_N PF00108.18 CBK25398.2 - 0.00026 20.0 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain AlaDh_PNT_C PF01262.16 CBK25398.2 - 0.00037 20.1 3.9 0.00063 19.3 0.2 3.3 5 0 0 5 5 4 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 CBK25398.2 - 0.003 17.0 0.1 0.42 9.9 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBK25398.2 - 0.0042 17.1 0.1 3.9 7.4 0.1 3.7 3 0 0 3 3 3 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBK25398.2 - 0.27 11.0 4.1 0.12 12.1 0.5 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_C1 PF00112.18 CBK25399.2 - 4.4e-99 330.7 21.2 4.2e-56 190.2 4.4 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBK25399.2 - 0.048 12.1 10.2 0.15 10.5 0.5 3.1 3 0 0 3 3 3 0 Peptidase C1-like family Methyltransf_15 PF09445.5 CBK25400.2 - 7.5e-21 74.3 0.3 1.5e-20 73.4 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CBK25400.2 - 7.3e-08 32.4 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBK25400.2 - 3.6e-07 29.7 0.0 5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 CBK25400.2 - 8e-05 23.1 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBK25400.2 - 0.00021 20.4 0.0 0.00055 19.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 CBK25400.2 - 0.0048 16.5 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CBK25400.2 - 0.025 14.1 0.2 0.07 12.7 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 CBK25400.2 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DJ-1_PfpI PF01965.19 CBK25401.2 - 2.8e-15 56.0 0.3 4.2e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 CBK25401.2 - 0.018 14.4 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I GATase_3 PF07685.9 CBK25401.2 - 0.018 14.6 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain G-patch_2 PF12656.2 CBK25402.2 - 4.7e-14 51.9 0.0 7.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 DExH-box splicing factor binding site Aconitase PF00330.15 CBK25403.2 - 0.065 11.6 0.0 0.079 11.4 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) LRR_8 PF13855.1 CBK25403.2 - 6.7 6.5 7.9 2.8 7.7 0.5 3.0 2 2 2 5 5 4 0 Leucine rich repeat zf-UBR PF02207.15 CBK25405.2 - 6.9e-16 57.7 20.7 6.9e-16 57.7 14.4 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Amidohydro_1 PF01979.15 CBK25406.2 - 7e-17 62.0 2.4 2.7e-16 60.1 1.6 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBK25406.2 - 3.5e-07 29.9 0.4 1.9e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 CBK25406.2 - 2.3e-06 27.8 0.1 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CBK25406.2 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family DNA_pol_A PF00476.15 CBK25407.2 - 3e-62 210.4 0.0 2.5e-61 207.4 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase family A TB2_DP1_HVA22 PF03134.14 CBK25408.2 - 8.4e-13 47.8 3.8 9.7e-13 47.6 2.6 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_L6e PF01159.14 CBK25409.2 - 4.2e-23 81.6 0.2 3.9e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L6e Abi PF02517.11 CBK25410.2 - 6.9e-12 45.3 2.7 6.9e-12 45.3 1.9 1.9 1 1 1 2 2 2 1 CAAX protease self-immunity DUF1298 PF06974.8 CBK25410.2 - 0.024 14.4 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) ODV-E18 PF10717.4 CBK25411.2 - 0.0027 17.1 0.2 0.0031 16.9 0.1 1.1 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF2768 PF10966.3 CBK25411.2 - 0.0041 17.2 1.9 0.0049 16.9 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2768) TPPK_C PF12555.3 CBK25411.2 - 0.0049 16.5 1.2 0.0076 15.9 0.8 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal TMEM192 PF14802.1 CBK25411.2 - 0.017 13.9 0.8 0.019 13.7 0.6 1.0 1 0 0 1 1 1 0 TMEM192 family DUF3753 PF12575.3 CBK25411.2 - 0.019 14.7 1.2 0.02 14.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF2393 PF09624.5 CBK25411.2 - 0.028 13.9 0.4 0.033 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) EcsB PF05975.7 CBK25411.2 - 0.036 12.5 3.3 0.042 12.3 2.3 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB BPD_transp_1 PF00528.17 CBK25411.2 - 0.045 13.2 0.5 0.044 13.2 0.4 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Rifin_STEVOR PF02009.11 CBK25411.2 - 0.058 13.0 3.3 0.056 13.0 2.3 1.0 1 0 0 1 1 1 0 Rifin/stevor family DUF997 PF06196.7 CBK25411.2 - 0.085 12.3 1.0 0.086 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF997) SP_C-Propep PF08999.5 CBK25411.2 - 0.11 12.0 1.1 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Syndecan PF01034.15 CBK25411.2 - 0.13 11.9 2.3 0.14 11.8 1.6 1.2 1 0 0 1 1 1 0 Syndecan domain Baculo_E56 PF04639.7 CBK25411.2 - 0.14 10.7 0.7 0.15 10.6 0.5 1.0 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Baculo_11_kDa PF06143.6 CBK25411.2 - 0.64 9.4 6.0 0.81 9.0 4.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Tmemb_9 PF05434.6 CBK25411.2 - 0.72 9.5 2.5 0.86 9.3 1.7 1.0 1 0 0 1 1 1 0 TMEM9 Synaptobrevin PF00957.16 CBK25411.2 - 6.8 6.3 5.8 8.5 6.0 4.0 1.1 1 0 0 1 1 1 0 Synaptobrevin DUF1777 PF08648.7 CBK25412.2 - 3.2e-13 49.8 21.2 3.7e-13 49.6 14.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 CBK25412.2 - 0.033 13.1 15.3 0.04 12.8 10.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein THRAP3_BCLAF1 PF15440.1 CBK25412.2 - 0.51 8.9 22.6 0.59 8.7 15.7 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF619 PF04768.8 CBK25414.2 - 0.028 13.8 0.5 0.037 13.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF619) Dicistro_VP4 PF11492.3 CBK25414.2 - 0.035 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 SGT1 PF07093.6 CBK25414.2 - 0.04 12.3 4.7 0.042 12.2 3.3 1.0 1 0 0 1 1 1 0 SGT1 protein DDHD PF02862.12 CBK25414.2 - 0.21 11.3 5.8 0.22 11.3 4.0 1.1 1 0 0 1 1 1 0 DDHD domain rRNA_processing PF08524.6 CBK25414.2 - 0.22 11.3 10.0 0.3 10.8 6.7 1.3 1 1 0 1 1 1 0 rRNA processing PBP_sp32 PF07222.7 CBK25414.2 - 0.72 8.9 4.5 0.81 8.8 3.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 CBK25414.2 - 1.1 7.1 6.5 1.3 7.0 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 CBK25414.2 - 5.9 7.2 11.1 1.5 9.1 5.3 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RabGAP-TBC PF00566.13 CBK25415.2 - 5.7e-05 22.6 0.2 0.016 14.6 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Beach PF02138.13 CBK25417.2 - 1.9e-58 198.0 0.7 3.2e-58 197.3 0.5 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.20 CBK25417.2 - 0.0023 17.1 0.2 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBK25417.2 - 0.036 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 CBK25418.2 - 1.5e-08 34.1 2.4 9.4e-05 22.1 0.4 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_11 PF13414.1 CBK25419.2 - 1.6e-24 85.3 10.8 1.1e-07 31.3 0.0 6.3 6 1 0 6 6 6 3 TPR repeat TPR_1 PF00515.23 CBK25419.2 - 1.6e-23 81.2 3.5 0.0017 17.9 0.0 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBK25419.2 - 2.3e-20 70.7 15.6 0.00068 19.3 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBK25419.2 - 3.7e-15 56.1 4.5 0.0022 18.6 0.0 5.5 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBK25419.2 - 1.5e-14 52.8 13.6 0.00075 19.5 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBK25419.2 - 1.3e-13 50.5 5.9 3.7e-05 23.5 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBK25419.2 - 8.2e-13 47.1 10.3 0.0081 15.8 0.0 8.4 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBK25419.2 - 8.5e-13 48.4 4.7 0.41 11.0 0.0 6.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBK25419.2 - 1.2e-12 47.2 5.1 0.23 12.2 0.3 8.1 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBK25419.2 - 2.8e-11 43.1 13.4 7.5e-06 25.8 0.2 6.3 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBK25419.2 - 5.6e-07 28.8 5.2 0.5 10.2 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBK25419.2 - 1.9e-06 27.9 22.9 0.00029 20.9 0.6 6.6 3 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CBK25419.2 - 8.8e-06 24.9 2.0 0.0044 16.1 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBK25419.2 - 2e-05 24.7 12.3 2.2 8.9 0.0 8.7 10 1 1 11 11 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBK25419.2 - 0.0013 18.5 5.7 0.13 12.2 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBK25419.2 - 0.0086 16.4 0.0 1.3 9.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 CBK25419.2 - 0.045 13.3 0.1 7.3 6.1 0.0 3.0 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 HA2 PF04408.18 CBK25420.2 - 3.3e-22 78.4 0.1 7.8e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBK25420.2 - 1.8e-12 46.9 0.0 5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CBK25420.2 - 3e-11 43.1 0.0 6.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Actin PF00022.14 CBK25421.2 - 8e-110 366.9 0.0 9.6e-110 366.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBK25421.2 - 0.13 10.8 0.0 6.3 5.2 0.0 2.7 2 1 0 2 2 2 0 MreB/Mbl protein EIF_2_alpha PF07541.7 CBK25423.2 - 3.6e-22 78.2 0.0 6.7e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CBK25423.2 - 7.6e-14 51.5 0.4 1.3e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DnaJ PF00226.26 CBK25424.2 - 1.2e-23 82.5 1.5 1.7e-23 82.1 1.1 1.2 1 0 0 1 1 1 1 DnaJ domain DUF1706 PF08020.6 CBK25424.2 - 0.032 13.7 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) DUF3353 PF11833.3 CBK25424.2 - 0.081 12.3 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF3395 PF11875.3 CBK25426.2 - 9.2e-24 83.7 0.0 1e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) Lectin_leg-like PF03388.8 CBK25427.2 - 5.5e-39 133.6 1.2 7e-39 133.2 0.8 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CBK25427.2 - 1.1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain CIA30 PF08547.7 CBK25427.2 - 0.011 15.5 0.4 0.024 14.5 0.1 1.6 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) Ribosomal_L23 PF00276.15 CBK25430.2 - 2.4e-17 62.6 2.3 5.5e-17 61.4 1.6 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 DUF2089 PF09862.4 CBK25430.2 - 0.092 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Shikimate_DH PF01488.15 CBK25430.2 - 0.1 12.7 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inhibitor_I29 PF08246.7 CBK25431.2 - 0.0004 20.6 3.5 0.00045 20.4 0.2 2.3 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) DUF759 PF05537.6 CBK25432.2 - 0.033 12.9 0.1 0.036 12.8 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) NUFIP1 PF10453.4 CBK25432.2 - 0.11 11.9 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Carboxyl_trans PF01039.17 CBK25433.2 - 6.8e-191 634.8 0.1 8.1e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBK25433.2 - 0.011 14.9 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) Lactamase_B_2 PF12706.2 CBK25435.2 - 0.0046 16.5 0.1 0.0087 15.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RIP PF00161.14 CBK25435.2 - 0.023 13.8 0.8 0.051 12.7 0.1 1.8 2 0 0 2 2 2 0 Ribosome inactivating protein DNA_topoisoIV PF00521.15 CBK25436.2 - 1.6e-122 409.4 0.0 1.6e-122 409.4 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBK25436.2 - 1.7e-26 92.4 1.7 6.3e-26 90.6 1.2 2.0 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CBK25436.2 - 3.1e-11 43.1 0.0 1.3e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CBK25436.2 - 4.9e-10 39.0 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Collagen PF01391.13 CBK25438.2 - 0.00015 21.2 10.1 0.00015 21.2 7.0 2.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Neisseria_TspB PF05616.8 CBK25438.2 - 1.7 6.9 4.1 2.2 6.5 2.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Helicase_C_2 PF13307.1 CBK25439.2 - 5.9e-52 175.9 0.1 3.5e-51 173.4 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBK25439.2 - 9.8e-33 112.9 3.1 2.6e-32 111.6 2.2 1.8 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CBK25439.2 - 1.7e-05 24.3 0.0 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CBK25439.2 - 0.00023 20.7 1.0 0.00056 19.5 0.7 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBK25439.2 - 0.00028 20.7 0.2 0.036 13.8 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ComJ PF11033.3 CBK25439.2 - 0.028 14.0 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Competence protein J (ComJ) PhoH PF02562.11 CBK25439.2 - 0.092 11.9 0.1 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein GAS PF13851.1 CBK25439.2 - 0.16 11.1 4.5 0.61 9.2 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MORN_2 PF07661.8 CBK25440.2 - 0.18 11.9 5.1 0.25 11.4 0.5 3.5 3 0 0 3 3 3 0 MORN repeat variant Aldo_ket_red PF00248.16 CBK25441.2 - 4.1e-55 186.6 0.0 4.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.21 CBK25443.2 - 4.3e-07 29.4 0.1 4.8e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reprolysin_2 PF13574.1 CBK25445.2 - 0.011 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-Sec23_Sec24 PF04810.10 CBK25445.2 - 0.033 13.7 0.5 0.066 12.7 0.3 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger CPDase PF07823.6 CBK25445.2 - 0.1 12.0 0.1 6.5 6.1 0.0 2.0 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Utp21 PF04192.7 CBK25446.2 - 2.2e-27 95.7 0.1 1.8e-25 89.4 0.1 2.1 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CBK25446.2 - 4.2e-18 64.4 12.8 0.022 14.6 0.0 8.9 9 0 0 9 9 9 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CBK25446.2 - 0.015 13.6 0.0 0.027 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.3 CBK25446.2 - 0.045 11.8 0.2 13 3.7 0.0 3.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 UTP15_C PF09384.5 CBK25446.2 - 0.11 12.2 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 UTP15 C terminal DUF2370 PF10176.4 CBK25446.2 - 0.23 10.7 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) zf-C2H2_4 PF13894.1 CBK25447.2 - 7.4 7.1 16.5 3.4 8.2 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger He_PIG PF05345.7 CBK25448.2 - 0.00023 21.1 0.0 0.001 19.0 0.0 2.1 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.15 CBK25448.2 - 0.0029 17.9 3.3 0.034 14.5 0.3 2.6 2 0 0 2 2 2 1 Sushi domain (SCR repeat) TMEM154 PF15102.1 CBK25448.2 - 0.013 15.2 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.1 CBK25448.2 - 0.055 12.9 0.6 0.12 11.7 0.4 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF912 PF06024.7 CBK25448.2 - 0.099 12.7 0.4 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_M24 PF00557.19 CBK25449.2 - 8.2e-43 146.3 0.0 1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HSP90 PF00183.13 CBK25449.2 - 4.9 5.4 14.0 6.7 4.9 9.7 1.1 1 0 0 1 1 1 0 Hsp90 protein Na_H_antiporter PF03553.9 CBK25450.2 - 1.9e-40 138.7 35.2 2.4e-40 138.4 10.8 2.5 1 1 1 2 2 2 2 Na+/H+ antiporter family tRNA-synt_1g PF09334.6 CBK25451.2 - 6e-140 466.3 0.1 9.6e-140 465.6 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBK25451.2 - 2.1e-09 35.9 0.5 0.0003 18.9 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) zf-ribbon_3 PF13248.1 CBK25451.2 - 0.0095 15.1 4.2 1.8 7.8 1.6 3.3 2 0 0 2 2 2 2 zinc-ribbon domain PDDEXK_1 PF12705.2 CBK25451.2 - 0.027 13.8 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DZR PF12773.2 CBK25451.2 - 0.067 13.0 8.2 0.62 9.9 5.7 2.7 1 1 0 1 1 1 0 Double zinc ribbon PglZ PF08665.7 CBK25451.2 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 PglZ domain zf-RING_3 PF14369.1 CBK25451.2 - 0.53 10.3 5.0 0.12 12.3 0.8 2.0 2 0 0 2 2 2 0 zinc-finger zf-C3HC4_3 PF13920.1 CBK25451.2 - 1.3 8.7 4.4 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cnd1 PF12717.2 CBK25452.2 - 1.6e-48 164.8 0.0 2.2e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBK25452.2 - 7.4e-07 27.8 0.0 1.1e-06 27.2 0.0 1.2 1 1 0 1 1 1 1 Adaptin N terminal region Nipped-B_C PF12830.2 CBK25452.2 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus HEAT PF02985.17 CBK25452.2 - 0.017 15.1 0.1 0.97 9.6 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 CBK25452.2 - 0.073 13.3 0.0 0.21 11.8 0.0 1.8 1 1 1 2 2 2 0 HEAT repeats RRM_1 PF00076.17 CBK25453.2 - 3.2e-27 93.9 0.0 4.4e-12 45.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBK25453.2 - 1.5e-21 76.1 0.0 7.7e-09 35.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK25453.2 - 5.7e-17 61.3 0.1 3.2e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBK25453.2 - 6.4e-09 35.4 0.0 0.00053 19.6 0.0 3.6 3 1 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBK25453.2 - 4.5e-06 26.3 0.0 0.025 14.3 0.0 3.5 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM PF05172.8 CBK25453.2 - 8.3e-05 22.2 0.6 1.1 9.0 0.0 3.7 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Ribosomal_L5_C PF00673.16 CBK25454.2 - 2.6e-22 78.3 0.0 3.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBK25454.2 - 2.6e-18 65.5 0.5 1.4e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 AP_endonuc_2 PF01261.19 CBK25455.2 - 2.3e-23 82.6 0.0 3.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel EcoRI PF02963.11 CBK25455.2 - 0.059 12.1 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRI Utp12 PF04003.7 CBK25456.2 - 1.1e-13 51.0 1.1 2.2e-13 50.0 0.8 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Mitofilin PF09731.4 CBK25457.2 - 0.00069 18.3 9.7 0.00074 18.2 6.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Lin-8 PF03353.10 CBK25457.2 - 0.1 11.9 18.5 0.13 11.5 12.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.1 CBK25457.2 - 0.12 11.6 14.4 0.17 11.1 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RGS-like PF09128.6 CBK25457.2 - 0.18 11.2 9.2 0.32 10.4 6.4 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Ycf1 PF05758.7 CBK25457.2 - 0.18 9.4 8.3 0.21 9.2 5.8 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CBK25457.2 - 0.3 10.9 9.8 0.54 10.1 6.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 CBK25457.2 - 0.34 9.2 12.8 0.41 9.0 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHHW PF14286.1 CBK25457.2 - 0.49 9.6 12.0 0.73 9.0 8.3 1.2 1 0 0 1 1 1 0 DHHW protein DUF913 PF06025.7 CBK25457.2 - 1.2 7.7 8.5 1.9 7.1 5.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ebola_NP PF05505.7 CBK25457.2 - 1.2 7.0 20.5 2.3 6.2 14.2 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein FLO_LFY PF01698.11 CBK25457.2 - 1.4 7.6 10.2 2.7 6.7 7.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 CBK25457.2 - 1.9 6.3 16.4 2.8 5.8 11.4 1.3 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.1 CBK25457.2 - 3.3 7.8 10.1 7.8 6.6 7.0 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Kei1 PF08552.6 CBK25457.2 - 4.1 7.0 4.6 6.8 6.2 3.2 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2201_N PF13203.1 CBK25457.2 - 4.5 6.3 23.3 13 4.8 0.1 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain FAM60A PF15396.1 CBK25457.2 - 5.9 6.5 7.9 8.8 6.0 5.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF2265 PF10023.4 CBK25457.2 - 9.6 5.2 16.5 13 4.7 11.4 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Cob_adeno_trans PF01923.13 CBK25458.2 - 2.5e-47 160.7 0.0 2.9e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF4389 PF14333.1 CBK25458.2 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) ATP-grasp_5 PF13549.1 CBK25459.2 - 3.4e-54 183.4 0.0 4.8e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CBK25459.2 - 5e-40 136.2 0.0 2.5e-39 134.0 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBK25459.2 - 4.5e-19 68.7 0.0 1.3e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain tRNA_bind PF01588.15 CBK25460.2 - 1.2e-18 66.6 0.0 1.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Glyco_transf_49 PF13896.1 CBK25460.2 - 2.6e-06 26.7 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 CBK25460.2 - 0.0013 17.8 0.1 0.0017 17.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 AalphaY_MDB PF04611.7 CBK25460.2 - 0.16 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region MatE PF01554.13 CBK25461.2 - 8.5e-26 90.5 23.6 1.1e-16 60.8 1.7 3.9 4 0 0 4 4 4 2 MatE Caenor_Her-1 PF09232.5 CBK25461.2 - 0.077 13.0 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Caenorhabditis elegans Her-1 Pkinase PF00069.20 CBK25462.2 - 0.00034 19.8 0.3 0.0043 16.2 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Imm23 PF15593.1 CBK25462.2 - 0.08 13.1 0.2 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 23 His_Phos_2 PF00328.17 CBK25464.2 - 5.4e-57 193.6 0.9 7.7e-57 193.1 0.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CBK25464.2 - 2.8e-05 23.6 0.0 5.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 CBK25464.2 - 0.002 18.2 0.0 0.0058 16.7 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ECR1_N PF14382.1 CBK25464.2 - 0.093 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region BCNT PF07572.7 CBK25465.2 - 2.4e-21 75.4 7.6 2.4e-21 75.4 5.2 2.4 3 0 0 3 3 3 1 Bucentaur or craniofacial development Glyco_hydro_47 PF01532.15 CBK25466.2 - 9.2e-121 403.6 1.7 1.1e-120 403.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_6 PF14259.1 CBK25467.2 - 5.9e-16 58.2 0.0 8.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBK25467.2 - 8.8e-14 50.9 0.0 1.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBK25467.2 - 3.9e-06 26.6 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WAK PF08488.6 CBK25468.2 - 0.055 13.7 0.1 0.063 13.5 0.1 1.1 1 0 0 1 1 1 0 Wall-associated kinase PTEN_C2 PF10409.4 CBK25469.2 - 1.8e-06 27.6 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 CBK25469.2 - 0.00011 21.5 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBK25469.2 - 0.0051 16.3 0.1 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBK25469.2 - 0.006 16.8 0.2 0.006 16.8 0.2 2.2 3 0 0 3 3 3 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 CBK25469.2 - 0.029 13.7 0.1 0.059 12.7 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 CBK25469.2 - 0.085 12.2 0.2 0.18 11.2 0.2 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AMP-binding PF00501.23 CBK25470.2 - 4.4e-15 55.0 0.1 3.3e-13 48.8 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme RLL PF10036.4 CBK25470.2 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Mito_carr PF00153.22 CBK25471.2 - 1.8e-49 165.3 0.7 3.2e-18 65.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.7 CBK25472.2 - 1.1e-16 61.0 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBK25472.2 - 1.9e-10 40.4 0.0 2.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBK25472.2 - 2.9e-10 40.0 0.0 4.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBK25472.2 - 9.7e-10 39.0 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBK25472.2 - 1.1e-09 38.5 0.1 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBK25472.2 - 5.3e-09 36.4 0.0 8.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBK25472.2 - 4e-06 26.8 0.1 7.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBK25472.2 - 1.4e-05 24.3 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CBK25472.2 - 2.1e-05 23.7 0.0 3.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 CBK25472.2 - 8.8e-05 21.3 0.1 0.00021 20.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 CBK25472.2 - 0.00027 20.6 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 CBK25472.2 - 0.00039 19.8 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 CBK25472.2 - 0.00077 18.8 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 CBK25472.2 - 0.036 13.2 0.0 0.069 12.3 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF726 PF05277.7 CBK25473.2 - 5.3e-33 114.3 0.1 5.7e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF2305 PF10230.4 CBK25473.2 - 0.013 14.9 0.0 0.017 14.5 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 CBK25473.2 - 0.033 13.9 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family PFK PF00365.15 CBK25474.2 - 2e-13 49.9 0.0 1.1e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Phosphofructokinase TCR PF03638.10 CBK25475.2 - 2.3e-24 84.9 51.2 2.8e-13 49.4 10.2 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain IP_trans PF02121.13 CBK25476.2 - 5.1e-39 133.9 7.2 1.6e-38 132.3 5.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein DUF2505 PF10698.4 CBK25476.2 - 0.0063 16.0 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) HA2 PF04408.18 CBK25477.2 - 6e-25 87.2 0.1 2.4e-24 85.2 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBK25477.2 - 1.7e-23 82.6 0.0 4.2e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 CBK25477.2 - 6.1e-14 51.8 0.1 1.7e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 CBK25477.2 - 3.1e-12 46.1 0.1 2.9e-11 43.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBK25477.2 - 4.4e-08 32.8 0.2 1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBK25477.2 - 1.1e-06 28.7 0.1 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBK25477.2 - 9.3e-06 24.7 0.1 2.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CBK25477.2 - 0.00031 20.4 0.1 0.00071 19.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 CBK25477.2 - 0.0018 18.0 0.1 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_25 PF13481.1 CBK25477.2 - 0.0069 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MIP-T3 PF10243.4 CBK25477.2 - 0.0075 14.7 10.5 0.011 14.2 7.2 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 ResIII PF04851.10 CBK25477.2 - 0.0086 15.9 0.9 2.5 7.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CBK25477.2 - 0.0093 15.8 0.7 0.14 12.0 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBK25477.2 - 0.016 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBK25477.2 - 0.022 15.0 0.2 0.42 10.8 0.1 2.8 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 CBK25477.2 - 0.022 14.2 1.9 0.078 12.4 0.0 2.8 3 1 1 4 4 4 0 FtsK/SpoIIIE family KaiC PF06745.8 CBK25477.2 - 0.034 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CBK25477.2 - 0.059 12.5 0.1 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Zip PF02535.17 CBK25477.2 - 7.1 5.5 6.3 11 4.8 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.20 CBK25478.2 - 1.5e-33 116.0 0.0 1.5e-33 116.0 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25478.2 - 2e-10 40.1 0.0 4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBK25478.2 - 3.5e-05 23.6 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBK25478.2 - 0.016 14.2 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Armet PF10208.4 CBK25479.2 - 2.5e-19 69.4 6.2 3.8e-19 68.8 4.3 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 CBK25479.2 - 0.0032 16.9 0.1 0.0072 15.8 0.0 1.7 2 0 0 2 2 2 1 SAP domain HLH PF00010.21 CBK25480.2 - 6.7e-09 35.3 4.0 6.7e-09 35.3 2.8 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain FlgN PF05130.7 CBK25480.2 - 0.094 12.9 1.6 0.16 12.2 1.1 1.3 1 0 0 1 1 1 0 FlgN protein DUF3847 PF12958.2 CBK25480.2 - 0.39 10.5 5.6 0.08 12.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) SPX PF03105.14 CBK25480.2 - 2.8 7.6 7.9 16 5.1 5.7 1.8 1 1 0 1 1 1 0 SPX domain DSPc PF00782.15 CBK25481.2 - 3e-18 65.6 0.3 5.4e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Chal_sti_synt_C PF02797.10 CBK25481.2 - 0.001 18.9 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 Chalcone and stilbene synthases, C-terminal domain CDKN3 PF05706.7 CBK25481.2 - 0.0017 17.8 0.5 0.0032 16.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) EF1_GNE PF00736.14 CBK25481.2 - 0.013 15.2 0.8 0.021 14.4 0.1 1.7 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain Init_tRNA_PT PF04179.7 CBK25481.2 - 0.015 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase MAM33 PF02330.11 CBK25482.2 - 9e-14 51.7 5.9 1.4e-13 51.0 4.1 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF4300 PF14133.1 CBK25482.2 - 0.039 13.2 0.7 0.076 12.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4300) tRNA-synt_1c PF00749.16 CBK25483.2 - 0.0055 15.4 4.5 0.0061 15.2 3.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain G-alpha PF00503.15 CBK25483.2 - 0.017 13.8 4.8 0.02 13.5 3.3 1.2 1 0 0 1 1 1 0 G-protein alpha subunit EURL PF06937.6 CBK25483.2 - 0.068 12.5 4.1 0.075 12.4 2.8 1.1 1 0 0 1 1 1 0 EURL protein DUF45 PF01863.12 CBK25483.2 - 0.071 12.8 4.3 0.08 12.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 TROVE PF05731.6 CBK25483.2 - 0.094 11.4 5.8 0.11 11.2 4.0 1.1 1 0 0 1 1 1 0 TROVE domain SspB PF04386.8 CBK25483.2 - 0.24 10.9 2.9 0.48 10.0 2.0 1.5 1 0 0 1 1 1 0 Stringent starvation protein B IncA PF04156.9 CBK25483.2 - 0.35 10.4 3.1 0.42 10.1 2.1 1.2 1 0 0 1 1 1 0 IncA protein DUF1115 PF06544.7 CBK25483.2 - 1.5 8.5 5.8 2.2 7.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Pribosyl_synth PF14572.1 CBK25483.2 - 1.9 8.2 4.0 1.6 8.4 0.1 2.0 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain DUF4557 PF15101.1 CBK25483.2 - 2 8.1 6.0 2.1 8.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 CBK25483.2 - 2.5 5.6 7.8 2.6 5.6 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RelB PF04221.7 CBK25483.2 - 6.8 6.5 8.0 1.3 8.8 0.3 3.0 1 1 3 4 4 4 0 RelB antitoxin DUF3464 PF11947.3 CBK25483.2 - 7.6 5.9 8.2 11 5.4 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) HABP4_PAI-RBP1 PF04774.10 CBK25484.2 - 5.6e-11 42.8 12.8 5.6e-11 42.8 8.9 4.5 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Myb_DNA-binding PF00249.26 CBK25485.2 - 9.2e-12 44.8 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBK25485.2 - 2.7e-06 27.3 0.1 5.2e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lyase_aromatic PF00221.14 CBK25486.2 - 3.9e-167 556.4 0.0 4.5e-167 556.2 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Glycos_transf_2 PF00535.21 CBK25487.2 - 2.6e-28 98.8 0.0 3.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBK25487.2 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBK25487.2 - 0.0013 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HIT PF01230.18 CBK25488.2 - 8.8e-19 67.8 0.0 1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBK25488.2 - 5.3e-05 23.4 0.0 6.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CBK25488.2 - 0.0054 16.3 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Herpes_DNAp_acc PF04929.7 CBK25488.2 - 0.083 11.8 0.0 0.098 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Metallophos PF00149.23 CBK25489.2 - 4.7e-38 130.5 0.0 5.9e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 CBK25490.2 - 3.1e-14 51.1 0.2 1.6e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBK25490.2 - 3e-13 49.6 0.0 8.6e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBK25490.2 - 4.3e-12 44.8 0.9 0.00011 21.8 0.1 4.6 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CBK25490.2 - 1.1e-10 40.9 0.0 0.016 14.7 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBK25490.2 - 8.4e-05 21.7 2.4 0.013 14.7 0.1 3.2 3 0 0 3 3 3 2 EF hand OrfB_Zn_ribbon PF07282.6 CBK25490.2 - 0.04 13.5 0.7 2.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HypA PF01155.14 CBK25490.2 - 0.23 11.1 0.9 2.5 7.8 0.1 2.4 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 CBK25490.2 - 0.29 10.8 2.0 0.76 9.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBK25490.2 - 0.32 10.6 2.1 0.83 9.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain AMP-binding PF00501.23 CBK25491.2 - 3.9e-76 256.1 0.0 4.7e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CBK25492.2 - 8.6e-66 222.0 0.1 1e-65 221.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pacs-1 PF10254.4 CBK25493.2 - 3.6e-06 25.8 0.0 3.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 PACS-1 cytosolic sorting protein Oxidored-like PF09791.4 CBK25493.2 - 0.034 13.5 0.1 0.034 13.5 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal Allene_ox_cyc PF06351.6 CBK25493.2 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Allene oxide cyclase UPF0054 PF02130.12 CBK25494.2 - 3.8e-29 100.8 0.0 4.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Peptidase_M10 PF00413.19 CBK25494.2 - 0.012 15.3 0.1 0.021 14.5 0.1 1.6 1 1 0 1 1 1 0 Matrixin RB_B PF01857.15 CBK25495.2 - 0.0037 16.7 1.0 0.0086 15.5 0.7 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain RYDR_ITPR PF01365.16 CBK25495.2 - 0.035 13.3 2.6 0.072 12.3 1.8 1.5 1 0 0 1 1 1 0 RIH domain T2SF PF00482.18 CBK25495.2 - 0.2 11.5 1.8 0.4 10.6 0.6 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF4296 PF14129.1 CBK25495.2 - 0.41 10.8 10.1 0.32 11.1 2.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4296) ABC_tran PF00005.22 CBK25496.2 - 3.2e-54 182.9 0.0 5.6e-26 91.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CBK25496.2 - 1.4e-48 165.6 64.0 2.5e-28 99.0 17.9 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBK25496.2 - 8.2e-23 81.7 0.6 1.1e-08 35.3 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBK25496.2 - 2e-08 33.7 0.3 0.0054 15.9 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBK25496.2 - 1.7e-06 27.3 0.0 0.021 13.8 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 CBK25496.2 - 2.9e-06 27.1 0.0 0.0025 17.6 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CBK25496.2 - 0.00026 20.2 0.2 0.025 13.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBK25496.2 - 0.00031 21.1 8.4 0.0034 17.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.17 CBK25496.2 - 0.00073 19.0 1.1 0.57 9.5 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CBK25496.2 - 0.0017 17.8 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 CBK25496.2 - 0.0072 15.8 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 CBK25496.2 - 0.054 12.5 0.3 3.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 CBK25496.2 - 0.12 11.8 0.0 4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBK25496.2 - 0.14 11.9 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_4 PF12730.2 CBK25496.2 - 2.5 7.2 54.7 0.017 14.3 14.5 3.2 2 1 0 2 2 2 0 ABC-2 family transporter protein DASH_Duo1 PF08651.5 CBK25498.2 - 0.087 12.4 0.2 0.095 12.2 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 DASH_Dad2 PF08654.5 CBK25498.2 - 0.11 12.4 0.8 0.13 12.2 0.6 1.0 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF4322 PF14210.1 CBK25498.2 - 0.14 11.6 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) MORN PF02493.15 CBK25499.2 - 3.5e-47 155.3 76.7 1.7e-06 27.3 1.6 13.1 13 0 0 13 13 13 12 MORN repeat Metallophos_3 PF14582.1 CBK25500.2 - 0.037 13.1 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Bac_chlorC PF02043.12 CBK25500.2 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein DUF3441 PF11923.3 CBK25500.2 - 0.12 11.9 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) Myc_N PF01056.13 CBK25501.2 - 0.0048 16.1 12.8 0.0079 15.3 8.9 1.4 1 0 0 1 1 1 1 Myc amino-terminal region TPR_12 PF13424.1 CBK25501.2 - 0.0056 16.5 0.6 0.0056 16.5 0.4 2.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Sporozoite_P67 PF05642.6 CBK25501.2 - 0.28 9.0 4.2 0.39 8.5 2.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 CBK25501.2 - 0.63 8.9 7.8 1.2 8.0 5.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Adeno_terminal PF02459.10 CBK25501.2 - 1.8 6.6 7.6 2.2 6.3 5.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF2457 PF10446.4 CBK25501.2 - 2.4 6.7 18.3 4.1 6.0 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TLP-20 PF06088.6 CBK25501.2 - 3 7.5 7.9 5.1 6.7 5.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PI3K_1B_p101 PF10486.4 CBK25501.2 - 9.7 3.6 10.0 12 3.2 6.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hanta_G2 PF01561.11 CBK25502.2 - 4.5e-05 22.0 0.4 5.2e-05 21.8 0.2 1.0 1 0 0 1 1 1 1 Hantavirus glycoprotein G2 DUF912 PF06024.7 CBK25502.2 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OAD_gamma PF04277.8 CBK25502.2 - 0.029 14.7 0.9 0.042 14.2 0.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.1 CBK25502.2 - 0.046 14.1 0.9 0.15 12.4 0.8 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YbhQ PF11076.3 CBK25502.2 - 0.057 13.0 0.1 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ TMEM154 PF15102.1 CBK25502.2 - 0.061 13.0 0.1 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SP_C-Propep PF08999.5 CBK25502.2 - 0.077 12.4 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Sigma_reg_N PF13800.1 CBK25502.2 - 0.081 12.9 0.4 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Rifin_STEVOR PF02009.11 CBK25502.2 - 0.091 12.3 0.1 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Rifin/stevor family Baculo_11_kDa PF06143.6 CBK25502.2 - 0.11 11.9 2.0 0.19 11.1 1.4 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DAG1 PF05454.6 CBK25502.2 - 0.14 11.2 0.6 0.14 11.3 0.4 1.2 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Pkinase_Tyr PF07714.12 CBK25503.2 - 3.5e-68 229.4 0.0 4.1e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBK25503.2 - 1.6e-58 197.9 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBK25503.2 - 0.084 12.5 0.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ANTH PF07651.11 CBK25504.2 - 5.9e-09 35.0 0.3 1.1e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 ANTH domain Pkinase_Tyr PF07714.12 CBK25504.2 - 0.00033 19.8 0.0 0.00069 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_2 PF13465.1 CBK25505.2 - 3.4e-19 68.0 26.0 4e-07 29.9 0.4 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBK25505.2 - 2.3e-06 27.5 30.2 0.015 15.6 0.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CBK25505.2 - 0.002 18.2 33.2 0.0076 16.4 0.2 6.1 5 1 1 6 6 6 2 C2H2-type zinc-finger domain zf-BED PF02892.10 CBK25505.2 - 0.019 14.7 8.0 0.21 11.3 2.2 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 CBK25505.2 - 0.044 14.1 4.6 0.15 12.4 0.6 5.8 5 2 0 5 5 5 0 Zinc finger, C2H2 type Peptidase_C1 PF00112.18 CBK25506.2 - 3.3e-63 213.5 7.3 4e-63 213.2 5.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBK25506.2 - 3.8e-05 22.4 1.9 0.00034 19.2 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 CBK25507.2 - 4.5e-60 203.2 6.1 5.6e-60 202.9 4.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBK25507.2 - 1.5e-05 23.7 1.7 0.00015 20.3 0.2 2.3 2 0 0 2 2 2 2 Peptidase C1-like family UPF0118 PF01594.11 CBK25508.2 - 1.6e-13 50.3 9.5 2.3e-13 49.8 6.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 Cons_hypoth698 PF03601.9 CBK25508.2 - 0.068 11.7 1.3 0.11 11.1 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 698 UPF0104 PF03706.8 CBK25508.2 - 0.13 11.5 6.0 0.81 8.9 4.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) Sec23_trunk PF04811.10 CBK25509.2 - 7.5e-31 107.3 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBK25509.2 - 4.9e-15 54.8 1.6 7.6e-15 54.2 0.1 2.1 2 1 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CBK25509.2 - 6.6e-15 54.4 0.8 1.4e-14 53.3 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CBK25509.2 - 4.2e-09 36.8 0.0 1.7e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain VWA_2 PF13519.1 CBK25509.2 - 0.15 12.1 1.6 0.62 10.1 1.1 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain TnpV PF14198.1 CBK25509.2 - 0.2 11.5 0.0 0.52 10.2 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV MFS_1 PF07690.11 CBK25510.2 - 1.6e-23 83.0 56.5 3.2e-21 75.4 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CBK25510.2 - 2.9 6.2 23.3 0.4 9.0 9.8 3.0 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like DUF2160 PF09928.4 CBK25510.2 - 3.8 7.6 13.3 4.7 7.3 5.2 3.3 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2160) Med11 PF10280.4 CBK25511.2 - 0.00058 19.9 0.3 0.00067 19.6 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF148 PF02520.12 CBK25511.2 - 0.074 12.8 0.2 0.084 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 PHP PF02811.14 CBK25514.2 - 9.6e-13 48.2 0.1 1.4e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 PHP domain Tyr_Deacylase PF02580.11 CBK25515.2 - 6.7e-44 149.3 0.0 8.4e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ribosomal_S7e PF01251.13 CBK25516.2 - 5.6e-56 189.0 0.9 6.2e-56 188.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2040 PF09745.4 CBK25517.2 - 7.2e-22 77.5 26.0 7.2e-22 77.5 18.0 2.3 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) TFIIA_gamma_N PF02268.11 CBK25518.2 - 1.1e-08 34.4 0.0 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Peptidase_M20 PF01546.23 CBK25519.2 - 1.6e-19 70.1 0.0 2.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBK25519.2 - 0.0047 16.6 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Paired_CXXCH_1 PF09699.5 CBK25519.2 - 0.041 13.4 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Glyco_transf_22 PF03901.12 CBK25520.2 - 3.8e-74 250.1 30.1 4.5e-74 249.9 20.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NGP1NT PF08153.7 CBK25521.2 - 8.1e-41 139.0 0.3 8.1e-41 139.0 0.2 2.1 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBK25521.2 - 9.9e-20 70.6 0.6 8.7e-16 57.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBK25521.2 - 3.6e-06 26.3 0.2 3.1e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 CBK25521.2 - 0.00019 20.6 0.0 0.00046 19.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBK25521.2 - 0.002 17.6 0.2 0.3 10.4 0.0 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CBK25521.2 - 0.0035 16.6 0.6 0.19 10.9 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family cobW PF02492.14 CBK25521.2 - 0.04 13.3 0.2 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CBK25521.2 - 0.075 13.5 4.2 3.7 8.0 0.2 2.9 3 0 0 3 3 3 0 Miro-like protein Dynamin_N PF00350.18 CBK25521.2 - 0.4 10.4 11.2 5.6 6.7 3.6 4.3 2 2 0 2 2 2 0 Dynamin family Vmethyltransf_C PF08456.5 CBK25521.2 - 4.1 6.7 11.7 0.23 10.8 0.1 2.4 2 0 0 2 2 2 0 Viral methyltransferase C-terminal Ribosomal_L36e PF01158.13 CBK25522.2 - 1.3e-24 86.0 5.4 1.6e-24 85.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dak2 PF02734.12 CBK25522.2 - 0.064 12.9 0.1 0.071 12.7 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain ArfGap PF01412.13 CBK25522.2 - 0.084 12.6 1.5 0.11 12.3 0.8 1.3 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf D5_N PF08706.6 CBK25522.2 - 0.13 12.3 1.8 0.15 12.1 1.2 1.1 1 0 0 1 1 1 0 D5 N terminal like CENP-H PF05837.7 CBK25522.2 - 1 9.5 4.6 2.1 8.5 0.7 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Triabin PF03973.8 CBK25524.2 - 0.12 12.0 0.1 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Triabin zf-met PF12874.2 CBK25525.2 - 5.2e-06 26.4 0.6 1.1e-05 25.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 CBK25525.2 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GATase_5 PF13507.1 CBK25525.2 - 0.035 13.0 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Band_7 PF01145.20 CBK25527.2 - 1.3e-24 87.0 3.2 2.3e-24 86.2 0.7 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2726 PF10881.3 CBK25527.2 - 0.056 13.0 2.1 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) NAGidase PF07555.8 CBK25527.2 - 0.15 10.9 0.2 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase PUA PF01472.15 CBK25528.2 - 5.3e-18 64.5 0.1 1.1e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 PUA domain DUF4292 PF14125.1 CBK25528.2 - 0.028 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Mito_carr PF00153.22 CBK25529.2 - 1.2e-55 185.2 1.6 2.3e-18 65.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.3 CBK25530.2 - 3.9e-09 36.4 24.1 2.6e-05 24.1 3.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3147) Neur_chan_memb PF02932.11 CBK25530.2 - 0.59 9.9 4.9 1.7 8.4 3.4 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.8 CBK25530.2 - 0.61 9.2 13.8 0.73 8.9 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1211 PF06736.6 CBK25530.2 - 1.7 8.8 11.5 5.6 7.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DUF1675 PF07897.6 CBK25530.2 - 2.9 7.6 14.6 4.5 7.0 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2217 PF10265.4 CBK25530.2 - 4.4 5.9 12.8 5.5 5.6 8.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ArfGap PF01412.13 CBK25531.2 - 4e-45 152.3 1.0 5.6e-45 151.8 0.7 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ABC_tran PF00005.22 CBK25532.2 - 7.1e-34 117.0 0.0 1.3e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBK25532.2 - 2.7e-14 53.8 7.0 0.0089 16.0 0.0 4.5 3 2 1 5 5 4 4 AAA domain SMC_N PF02463.14 CBK25532.2 - 1.5e-13 50.5 1.9 0.00032 19.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 CBK25532.2 - 7.2e-12 44.6 3.4 7.2e-12 44.6 2.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 CBK25532.2 - 3.3e-08 32.8 3.0 3.3e-08 32.8 2.1 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.1 CBK25532.2 - 9.4e-08 31.5 0.2 0.44 9.5 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain Fer4_6 PF12837.2 CBK25532.2 - 4.3e-06 26.3 10.0 6.4e-06 25.7 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 CBK25532.2 - 1.2e-05 25.4 0.3 0.029 14.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CBK25532.2 - 3.1e-05 23.6 0.4 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 CBK25532.2 - 4.2e-05 23.7 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 CBK25532.2 - 5.3e-05 23.5 0.2 5.3e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain DUF258 PF03193.11 CBK25532.2 - 6.7e-05 22.1 0.0 0.36 10.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBK25532.2 - 9.5e-05 21.8 0.1 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 CBK25532.2 - 0.00015 21.3 1.4 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.2 CBK25532.2 - 0.00019 21.1 1.9 0.00019 21.1 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain MobB PF03205.9 CBK25532.2 - 0.0002 21.1 0.7 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBK25532.2 - 0.00026 21.8 0.7 0.11 13.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBK25532.2 - 0.00026 20.8 0.1 0.12 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBK25532.2 - 0.00042 20.3 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.1 CBK25532.2 - 0.00053 20.2 2.3 0.00053 20.2 1.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_23 PF13476.1 CBK25532.2 - 0.0006 20.2 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBK25532.2 - 0.00063 20.2 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SbcCD_C PF13558.1 CBK25532.2 - 0.00064 19.5 0.0 0.17 11.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 CBK25532.2 - 0.00075 19.0 0.0 0.79 9.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_10 PF13237.1 CBK25532.2 - 0.0012 18.5 1.7 0.0012 18.5 1.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 CBK25532.2 - 0.0015 18.6 0.0 2.7 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 CBK25532.2 - 0.0019 17.8 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_16 PF13484.1 CBK25532.2 - 0.002 18.8 0.2 0.002 18.8 0.1 2.2 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain AAA_18 PF13238.1 CBK25532.2 - 0.0034 17.6 0.0 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBK25532.2 - 0.0042 15.8 0.1 0.059 12.0 0.0 2.4 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 CBK25532.2 - 0.0058 16.4 11.4 0.019 14.8 8.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CBK25532.2 - 0.0091 15.4 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CBK25532.2 - 0.012 15.3 0.6 1 9.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_3 PF12798.2 CBK25532.2 - 0.013 16.0 4.7 0.013 16.0 3.2 2.2 2 0 0 2 2 1 0 4Fe-4S binding domain DUF815 PF05673.8 CBK25532.2 - 0.017 14.0 0.1 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 CBK25532.2 - 0.018 14.3 0.1 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 CBK25532.2 - 0.022 14.7 1.7 1.9 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Fer4_15 PF13459.1 CBK25532.2 - 0.023 15.2 0.6 0.073 13.6 0.5 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain AAA_30 PF13604.1 CBK25532.2 - 0.024 14.1 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBK25532.2 - 0.036 13.9 0.1 5.6 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CBK25532.2 - 0.036 14.4 2.5 0.036 14.4 1.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain TrwB_AAD_bind PF10412.4 CBK25532.2 - 0.038 12.6 0.2 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 CBK25532.2 - 0.062 12.9 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CBK25532.2 - 0.076 12.7 1.2 10 5.8 0.0 3.1 3 0 0 3 3 2 0 NTPase KAP_NTPase PF07693.9 CBK25532.2 - 0.092 11.7 0.0 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 CBK25532.2 - 0.11 11.3 0.1 5.9 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CBK25532.2 - 0.14 11.6 0.9 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF359 PF04019.7 CBK25532.2 - 0.14 11.5 0.2 0.39 10.1 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF359) AAA_24 PF13479.1 CBK25532.2 - 0.14 11.6 0.3 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBK25532.2 - 0.24 10.2 0.9 0.84 8.4 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_13 PF13166.1 CBK25532.2 - 0.34 9.3 1.2 0.53 8.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.1 CBK25532.2 - 0.6 10.1 8.5 0.098 12.7 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBK25532.2 - 3.3 8.1 8.8 0.49 10.8 2.9 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Carboxyl_trans PF01039.17 CBK25534.2 - 1.6e-133 445.6 0.1 2.1e-133 445.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain PSII_Pbs27 PF13326.1 CBK25534.2 - 0.34 10.8 1.4 7.4 6.5 0.3 2.3 2 0 0 2 2 2 0 Photosystem II Pbs27 Aa_trans PF01490.13 CBK25535.2 - 1.2e-26 93.1 19.6 1.6e-26 92.7 13.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spindle_Spc25 PF08234.7 CBK25536.2 - 4.3e-17 61.8 0.5 1.4e-16 60.2 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 AAA_13 PF13166.1 CBK25536.2 - 0.18 10.1 17.8 0.036 12.5 10.1 1.3 2 0 0 2 2 2 0 AAA domain CENP-O PF09496.5 CBK25536.2 - 0.29 11.4 4.1 0.45 10.7 0.2 3.0 2 2 1 3 3 3 0 Cenp-O kinetochore centromere component APG6 PF04111.7 CBK25536.2 - 0.43 9.5 15.5 0.82 8.6 10.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 CBK25536.2 - 0.48 10.4 12.7 0.88 9.5 8.8 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF724 PF05266.9 CBK25536.2 - 0.49 9.9 19.7 0.021 14.4 9.2 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) CDC45 PF02724.9 CBK25536.2 - 0.51 8.3 9.5 0.69 7.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.4 CBK25536.2 - 0.99 8.2 13.9 1.4 7.7 9.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CBK25536.2 - 1.5 7.1 14.4 2 6.7 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDE_Tnp_IS66 PF03050.9 CBK25536.2 - 3.4 6.8 6.9 0.84 8.7 2.1 1.7 1 1 1 2 2 2 0 Transposase IS66 family DUF4407 PF14362.1 CBK25536.2 - 4.8 6.0 7.8 7 5.5 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TRAP_beta PF05753.9 CBK25537.2 - 8.6e-15 54.3 0.0 1.1e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.13 CBK25537.2 - 0.071 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF11 TPR_11 PF13414.1 CBK25538.2 - 0.15 11.7 2.3 2.2 7.9 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Pkinase PF00069.20 CBK25540.2 - 2.3e-45 154.7 0.7 3.6e-45 154.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBK25540.2 - 1.7e-22 79.7 0.0 2.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBK25540.2 - 0.0049 15.7 0.2 0.0049 15.7 0.2 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBK25540.2 - 0.0052 15.7 0.0 0.04 12.8 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBK25540.2 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CBK25541.2 - 8.1e-36 120.6 4.1 5.7e-10 38.6 0.3 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBK25541.2 - 5.6e-06 24.7 0.6 2.1e-05 22.8 0.2 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBK25541.2 - 0.049 12.3 0.0 4.9 5.8 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like IL10 PF00726.12 CBK25543.2 - 0.0022 17.3 0.0 0.029 13.6 0.0 2.4 2 1 1 3 3 3 1 Interleukin 10 eIF-6 PF01912.13 CBK25545.2 - 5.4e-81 270.4 0.4 7.8e-81 269.9 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family ATP-synt_C PF00137.16 CBK25546.2 - 4.5e-28 96.9 33.5 2.2e-16 59.5 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 CBK25546.2 - 0.022 14.3 0.7 0.022 14.3 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2970) KRTAP PF11759.3 CBK25546.2 - 0.8 9.9 9.3 0.41 10.9 2.6 2.3 2 0 0 2 2 2 0 Keratin-associated matrix BofA PF07441.6 CBK25546.2 - 0.9 9.5 12.7 1.1 9.3 1.2 2.9 3 0 0 3 3 3 0 SigmaK-factor processing regulatory protein BofA Flp_Fap PF04964.9 CBK25546.2 - 2.3 7.9 5.8 9.6 5.9 0.1 2.8 2 0 0 2 2 2 0 Flp/Fap pilin component UDPGP PF01704.13 CBK25547.2 - 0.0018 16.8 0.0 0.002 16.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Shigella_OspC PF06128.6 CBK25547.2 - 0.068 12.6 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein HSP70 PF00012.15 CBK25548.2 - 4.9e-75 252.6 0.0 6.1e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBK25548.2 - 6e-06 25.0 0.0 1.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Cyclin PF08613.6 CBK25549.2 - 1.7e-25 90.2 1.0 2.2e-25 89.7 0.7 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBK25549.2 - 1.3e-10 40.9 0.1 1.8e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF3_subunit PF08597.5 CBK25550.2 - 8.2e-21 74.6 7.6 9.6e-21 74.4 5.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Rad50_zn_hook PF04423.9 CBK25550.2 - 0.33 10.4 3.3 0.8 9.2 0.4 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif TBPIP PF07106.8 CBK25551.2 - 0.0097 15.4 54.1 0.06 12.8 8.6 4.2 1 1 3 4 4 4 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YbjQ_1 PF01906.12 CBK25551.2 - 0.014 15.8 2.8 0.018 15.4 0.4 2.4 2 0 0 2 2 2 0 Putative heavy-metal-binding Tropomyosin PF00261.15 CBK25551.2 - 0.015 14.4 50.8 0.059 12.4 14.9 4.2 1 1 3 4 4 4 0 Tropomyosin Lebercilin PF15619.1 CBK25551.2 - 0.65 9.3 62.1 0.31 10.4 16.0 3.3 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 CBK25551.2 - 0.76 8.8 16.7 0.093 11.8 1.6 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBK25551.2 - 1.1 7.6 44.8 0.068 11.6 17.9 2.7 1 1 2 3 3 3 0 AAA domain DUF2353 PF09789.4 CBK25551.2 - 1.2 8.3 48.6 4.4 6.4 15.2 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 CBK25551.2 - 1.2 8.7 67.7 0.49 9.9 8.4 3.5 1 1 3 4 4 4 0 IncA protein APG17 PF04108.7 CBK25551.2 - 1.3 7.7 41.3 0.9 8.2 11.5 3.1 1 1 2 3 3 3 0 Autophagy protein Apg17 Fib_alpha PF08702.5 CBK25551.2 - 2.1 8.4 53.9 0.043 13.9 10.1 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.16 CBK25551.2 - 3.6 6.9 66.0 1.9 7.8 13.9 3.8 1 1 5 6 6 6 0 Intermediate filament protein Lipoprotein_6 PF01441.14 CBK25551.2 - 4.1 7.2 19.9 0.029 14.2 3.7 2.7 2 2 0 2 2 2 0 Lipoprotein Borrelia_lipo_2 PF06238.6 CBK25552.2 - 0.11 12.5 0.3 0.11 12.5 0.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein LRR_8 PF13855.1 CBK25553.2 - 2.2e-05 24.1 1.8 0.17 11.6 0.0 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBK25553.2 - 0.041 13.5 1.9 5.4 6.7 0.0 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) 2OG-FeII_Oxy_4 PF13661.1 CBK25553.2 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily