# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Kelch_1 PF01344.25 PXF39383.1 - 3.8e-08 32.8 0.1 0.048 13.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 PXF39383.1 - 0.0022 18.3 0.0 22 5.5 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 PXF39383.1 - 0.0023 17.9 0.0 2.4 8.2 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF39383.1 - 0.011 16.0 0.8 16 5.9 0.0 3.7 4 1 0 4 4 4 0 Kelch motif STAT_alpha PF01017.20 PXF39386.1 - 0.0071 16.3 0.8 0.0086 16.0 0.8 1.0 1 0 0 1 1 1 1 STAT protein, all-alpha domain CaKB PF03185.15 PXF39391.1 - 0.068 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit zf-met2 PF12907.7 PXF39392.1 - 0.00036 20.6 3.9 0.0007 19.7 3.9 1.5 1 0 0 1 1 1 1 Zinc-binding DUF2428 PF10350.9 PXF39392.1 - 0.093 12.0 0.2 0.49 9.6 0.1 1.8 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Pkinase PF00069.25 PXF39393.1 - 7.5e-18 64.8 0.0 9.3e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF39393.1 - 4.4e-09 36.0 0.0 5.4e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 PXF39395.1 - 8.8e-10 38.3 0.1 2.7e-09 36.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like SPOC PF07744.13 PXF39395.1 - 4.5e-08 33.1 0.0 8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 SPOC domain F-box PF00646.33 PXF39395.1 - 4.8e-06 26.3 0.6 3.9e-05 23.4 0.0 2.4 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 PXF39395.1 - 0.005 16.7 0.1 0.0087 15.9 0.1 1.4 1 0 0 1 1 1 1 F-box Glyco_hydro_16 PF00722.21 PXF39396.1 - 0.0099 15.4 0.1 0.039 13.4 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Imm64 PF15600.6 PXF39396.1 - 0.02 14.5 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 64 Glyco_hydro_16 PF00722.21 PXF39397.1 - 0.0064 16.0 0.1 0.0064 16.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAP2 PF01569.21 PXF39399.1 - 0.026 14.3 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily DUF2457 PF10446.9 PXF39402.1 - 0.19 10.8 15.2 0.3 10.2 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MnmE_helical PF12631.7 PXF39403.1 - 0.011 15.9 1.8 0.02 15.1 0.9 1.7 2 0 0 2 2 2 0 MnmE helical domain NYD-SP28 PF14772.6 PXF39403.1 - 0.031 14.3 2.5 0.069 13.2 2.5 1.5 1 0 0 1 1 1 0 Sperm tail PADR1 PF08063.12 PXF39403.1 - 0.056 13.2 0.3 0.093 12.5 0.3 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain YabA PF06156.13 PXF39403.1 - 0.096 13.3 1.4 0.21 12.2 1.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA zinc_ribbon_4 PF13717.6 PXF39403.1 - 0.22 11.5 3.6 0.64 10.0 3.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 PXF39403.1 - 0.27 11.2 1.4 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 PhnA Zinc-Ribbon RRP7 PF12923.7 PXF39404.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Exo_endo_phos_2 PF14529.6 PXF39405.1 - 6.9e-13 48.5 0.7 1.1e-12 47.8 0.7 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF39405.1 - 0.0054 16.3 0.2 0.0069 15.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1382 PF07131.11 PXF39405.1 - 0.081 12.9 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) RVT_1 PF00078.27 PXF39406.1 - 3.6e-27 95.3 0.0 4.3e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1317 PF07026.11 PXF39406.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) DUF3421 PF11901.8 PXF39410.1 - 1.3e-36 125.1 2.1 1.5e-19 70.1 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) CaKB PF03185.15 PXF39412.1 - 0.099 12.3 0.3 0.096 12.3 0.3 1.0 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit RVT_2 PF07727.14 PXF39420.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ricin_B_lectin PF00652.22 PXF39433.1 - 3e-11 43.7 0.0 4.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glycos_transf_2 PF00535.26 PXF39434.1 - 1.5e-26 93.2 0.0 3.1e-26 92.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF39434.1 - 0.00013 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF39434.1 - 0.019 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF39435.1 - 4.9e-21 75.3 0.0 9.5e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 PXF39435.1 - 5.2e-09 35.6 0.2 1.3e-08 34.3 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PXF39435.1 - 6.8e-06 26.1 0.0 2.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF39435.1 - 0.00016 21.3 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Prefoldin_2 PF01920.20 PXF39437.1 - 4.4e-20 71.6 3.5 5e-20 71.4 3.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit V_ATPase_I PF01496.19 PXF39437.1 - 0.0038 15.2 0.8 0.0045 15.0 0.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Not3 PF04065.15 PXF39437.1 - 0.011 15.2 0.6 0.011 15.2 0.6 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component PP1_inhibitor PF05361.12 PXF39437.1 - 0.021 14.8 2.6 0.034 14.1 2.6 1.3 1 1 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor MetOD2 PF18548.1 PXF39437.1 - 0.048 13.8 1.9 0.4 10.8 0.2 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 DUF1664 PF07889.12 PXF39437.1 - 0.059 13.4 0.3 0.059 13.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 PXF39437.1 - 0.15 12.6 4.9 0.36 11.4 4.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region AD PF09793.9 PXF39437.1 - 0.22 11.7 0.3 0.22 11.7 0.3 1.8 2 0 0 2 2 2 0 Anticodon-binding domain Prefoldin PF02996.17 PXF39437.1 - 0.26 11.2 4.3 1.3 8.9 4.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF829 PF05705.14 PXF39438.1 - 6.6e-27 94.9 0.0 2.2e-26 93.3 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF5363 PF17320.2 PXF39438.1 - 0.011 15.6 2.0 0.011 15.6 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5363) DUF818 PF05677.12 PXF39440.1 - 0.12 11.3 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DEAD PF00270.29 PXF39443.1 - 3.4e-12 46.5 0.0 6.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF39443.1 - 4.8e-09 36.5 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF39443.1 - 7.7e-06 26.0 0.0 3.8e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_pol_Rpb1_5 PF04998.17 PXF39444.1 - 4.4e-09 36.2 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 MutS_V PF00488.21 PXF39445.1 - 1.2e-06 28.7 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 MutS domain V DBR1 PF05011.13 PXF39447.1 - 0.033 14.6 0.4 0.039 14.4 0.4 1.1 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain HTH_ParB PF17762.1 PXF39447.1 - 0.042 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 HTH domain found in ParB protein DUF4423 PF14394.6 PXF39447.1 - 0.083 12.6 1.6 0.095 12.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) dCMP_cyt_deam_1 PF00383.23 PXF39460.1 - 1.3e-23 82.8 0.2 1.7e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF39460.1 - 5.4e-19 68.3 0.0 6.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 PXF39460.1 - 0.001 19.2 0.3 0.0015 18.6 0.3 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 PXF39460.1 - 0.044 13.8 0.2 0.064 13.3 0.2 1.2 1 0 0 1 1 1 0 APOBEC2 HTH_11 PF08279.12 PXF39464.1 - 0.051 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 HTH domain WXG100 PF06013.12 PXF39465.1 - 0.0049 17.1 0.3 0.17 12.2 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG EzrA PF06160.12 PXF39465.1 - 0.029 12.6 2.7 0.038 12.2 2.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NAM-associated PF14303.6 PXF39465.1 - 2.2 9.0 13.1 0.52 11.0 6.3 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain CNOT1_CAF1_bind PF16415.5 PXF39466.1 - 6.8e-05 22.4 0.2 8.7e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF5556 PF17711.1 PXF39466.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5556) Ehrlichia_rpt PF09528.10 PXF39467.1 - 0.015 14.8 0.3 0.029 13.8 0.3 1.4 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Glyco_transf_34 PF05637.12 PXF39472.1 - 0.17 11.6 0.7 0.4 10.4 0.2 1.6 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family Nop14 PF04147.12 PXF39473.1 - 3e-58 197.9 35.3 7.4e-36 123.7 0.0 3.0 2 1 1 3 3 3 3 Nop14-like family Myc-LZ PF02344.15 PXF39473.1 - 0.7 10.0 7.8 2.2 8.4 7.8 1.9 1 0 0 1 1 1 0 Myc leucine zipper domain PAP_fibrillin PF04755.12 PXF39474.1 - 1.6e-12 47.8 0.0 3.2e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 PAP_fibrillin DAHP_synth_2 PF01474.16 PXF39475.1 - 9.1e-57 192.5 0.0 1e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Nop14 PF04147.12 PXF39480.1 - 0.038 12.2 6.1 0.04 12.1 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1104 PF06518.11 PXF39480.1 - 0.039 14.3 4.1 0.38 11.2 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) Kunitz_BPTI PF00014.23 PXF39481.1 - 0.00049 20.3 3.0 0.00075 19.7 1.6 2.1 2 0 0 2 2 2 1 Kunitz/Bovine pancreatic trypsin inhibitor domain PyrI_C PF02748.15 PXF39482.1 - 0.12 12.3 4.2 0.98 9.4 0.0 3.6 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Elf1 PF05129.13 PXF39482.1 - 0.14 12.2 8.1 1.8 8.7 1.4 3.4 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.13 PXF39482.1 - 0.2 11.4 1.0 0.51 10.1 1.0 1.7 1 0 0 1 1 1 0 InsA N-terminal domain zinc_ribbon_4 PF13717.6 PXF39482.1 - 1.9 8.5 12.8 0.72 9.8 0.7 3.5 3 1 1 4 4 4 0 zinc-ribbon domain Anti-TRAP PF15777.5 PXF39482.1 - 2.4 8.2 4.6 12 6.0 0.1 2.7 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PXF39482.1 - 4 7.5 7.1 1.6 8.8 2.0 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CcmH PF03918.14 PXF39482.1 - 5.1 6.4 5.8 15 4.9 1.8 3.1 3 1 0 3 3 3 0 Cytochrome C biogenesis protein Exo_endo_phos PF03372.23 PXF39483.1 - 0.00068 19.2 0.0 0.00086 18.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 PXF39484.1 - 1.5e-10 41.0 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 PXF39486.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CaKB PF03185.15 PXF39487.1 - 0.068 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit TPR_2 PF07719.17 PXF39488.1 - 5e-10 38.7 0.1 0.053 13.7 0.0 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF39488.1 - 2.2e-08 34.6 0.2 3.5e-06 27.6 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF39488.1 - 5.6e-07 30.0 0.0 0.00023 21.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF39488.1 - 7.1e-06 26.1 0.0 5.3e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF39488.1 - 2.3e-05 24.2 0.0 0.089 13.0 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF39488.1 - 3.1e-05 23.6 1.1 0.017 14.9 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF39488.1 - 3.5e-05 24.0 1.5 0.68 10.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF39488.1 - 6.3e-05 22.6 0.0 0.075 12.7 0.0 3.4 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 PXF39488.1 - 0.00017 22.1 0.1 0.53 11.2 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF39488.1 - 0.00031 20.5 0.1 1.5 9.0 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF39488.1 - 0.032 14.1 0.3 0.76 9.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PXF39488.1 - 0.047 13.9 0.0 1.5 9.0 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF39488.1 - 0.13 12.5 0.1 0.57 10.4 0.0 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CNOT1_CAF1_bind PF16415.5 PXF39493.1 - 6.8e-05 22.4 0.2 8.7e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF5556 PF17711.1 PXF39493.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5556) Nop14 PF04147.12 PXF39495.1 - 1.6e-19 69.7 6.6 3e-14 52.2 0.0 2.0 2 0 0 2 2 2 2 Nop14-like family DUF1104 PF06518.11 PXF39495.1 - 1.9 8.9 8.1 1.3 9.4 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) Nop14 PF04147.12 PXF39496.1 - 2.1e-30 105.7 26.1 2.4e-30 105.5 26.1 1.0 1 0 0 1 1 1 1 Nop14-like family Myc-LZ PF02344.15 PXF39496.1 - 0.23 11.6 7.8 0.65 10.1 7.8 1.8 1 0 0 1 1 1 0 Myc leucine zipper domain Nop14 PF04147.12 PXF39497.1 - 5.1e-11 41.6 8.9 5.2e-11 41.5 8.2 1.4 1 1 1 2 2 2 1 Nop14-like family Pkinase PF00069.25 PXF39498.1 - 3.8e-31 108.4 0.0 4.6e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF39498.1 - 3.3e-17 62.6 0.0 4.1e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF39498.1 - 0.00016 20.6 0.0 0.00027 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF39498.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Morc6_S5 PF17942.1 PXF39498.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like Kinase-like PF14531.6 PXF39498.1 - 0.21 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF676 PF05057.14 PXF39499.1 - 2.8e-20 72.8 0.1 3.8e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PXF39499.1 - 0.00087 19.2 0.1 0.0014 18.5 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cupin_1 PF00190.22 PXF39501.1 - 1.5e-07 31.2 0.1 2.2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF39501.1 - 2.5e-05 23.9 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 PXF39501.1 - 0.012 15.5 0.1 0.033 14.1 0.1 1.7 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase APG6_N PF17675.1 PXF39502.1 - 0.0001 22.8 1.2 0.00011 22.8 1.2 1.0 1 0 0 1 1 1 1 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 PXF39502.1 - 0.00014 22.0 0.9 0.00014 22.0 0.9 1.1 1 0 0 1 1 1 1 Tropomyosin like ZapB PF06005.12 PXF39502.1 - 0.00014 22.2 4.7 0.00016 22.0 4.7 1.1 1 0 0 1 1 1 1 Cell division protein ZapB ATG16 PF08614.11 PXF39502.1 - 0.00015 22.1 1.8 0.00017 21.9 1.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.9 PXF39502.1 - 0.0017 18.3 1.1 0.0019 18.2 1.1 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ADIP PF11559.8 PXF39502.1 - 0.0022 18.1 0.4 0.0025 17.9 0.4 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 PXF39502.1 - 0.0022 18.4 1.4 0.0025 18.2 1.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Phage_GP20 PF06810.11 PXF39502.1 - 0.0027 17.5 0.2 0.003 17.4 0.2 1.0 1 0 0 1 1 1 1 Phage minor structural protein GP20 Spc7 PF08317.11 PXF39502.1 - 0.003 16.5 1.8 0.0033 16.4 1.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3450 PF11932.8 PXF39502.1 - 0.0032 16.8 0.8 0.0036 16.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CAGE1 PF15066.6 PXF39502.1 - 0.0039 15.9 0.6 0.0039 15.9 0.6 1.1 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family LXG PF04740.12 PXF39502.1 - 0.0052 16.5 0.1 0.0054 16.5 0.1 1.0 1 0 0 1 1 1 1 LXG domain of WXG superfamily Laminin_II PF06009.12 PXF39502.1 - 0.0079 16.2 1.4 0.0092 16.0 1.4 1.1 1 0 0 1 1 1 1 Laminin Domain II Atg14 PF10186.9 PXF39502.1 - 0.0089 15.1 0.4 0.0089 15.1 0.4 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 RINT1_TIP1 PF04437.13 PXF39502.1 - 0.01 14.7 0.2 0.013 14.4 0.2 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family SlyX PF04102.12 PXF39502.1 - 0.019 15.6 2.5 0.027 15.1 2.5 1.3 1 0 0 1 1 1 0 SlyX MitMem_reg PF13012.6 PXF39502.1 - 0.023 15.1 0.1 0.026 15.0 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function ERM PF00769.19 PXF39502.1 - 0.024 14.4 3.9 0.029 14.2 3.9 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Nup54 PF13874.6 PXF39502.1 - 0.029 14.5 1.1 0.033 14.3 1.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin_2 PF14523.6 PXF39502.1 - 0.035 14.5 0.9 0.046 14.1 0.9 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF4142 PF13628.6 PXF39502.1 - 0.035 14.3 0.1 0.042 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) COG2 PF06148.11 PXF39502.1 - 0.036 14.1 1.2 0.047 13.8 1.2 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 PXF39502.1 - 0.037 14.0 6.6 0.05 13.6 6.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 PXF39502.1 - 0.039 14.2 1.8 0.044 14.0 1.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 PXF39502.1 - 0.043 14.2 3.8 0.054 13.9 3.8 1.1 1 0 0 1 1 1 0 Snapin/Pallidin YabA PF06156.13 PXF39502.1 - 0.043 14.4 0.8 0.053 14.2 0.8 1.2 1 0 0 1 1 1 0 Initiation control protein YabA GIT_CC PF16559.5 PXF39502.1 - 0.058 13.3 2.2 0.079 12.8 2.2 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3053 PF11254.8 PXF39502.1 - 0.073 12.7 0.4 0.082 12.5 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) FlaC_arch PF05377.11 PXF39502.1 - 0.099 13.0 2.5 0.14 12.5 0.6 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 PXF39502.1 - 0.11 11.1 0.4 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A XhlA PF10779.9 PXF39502.1 - 0.2 11.9 1.2 0.3 11.3 1.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 PXF39502.1 - 0.23 11.3 6.6 0.43 10.4 5.8 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF5595 PF18077.1 PXF39502.1 - 1.7 8.7 6.6 0.4 10.8 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) WD40_alt PF14077.6 PXF39502.1 - 4.4 7.2 7.4 13 5.7 2.6 2.4 1 1 1 2 2 2 0 Alternative WD40 repeat motif Josephin PF02099.17 PXF39503.1 - 2.3e-12 47.3 0.0 5.3e-09 36.4 0.0 2.4 1 1 1 2 2 2 2 Josephin TP_methylase PF00590.20 PXF39504.1 - 5.4e-39 134.3 0.5 7.7e-39 133.8 0.1 1.4 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF3040 PF11239.8 PXF39505.1 - 0.54 10.6 5.2 6.1 7.2 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Oleosin PF01277.17 PXF39506.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Oleosin INTS5_N PF14837.6 PXF39530.1 - 0.043 13.4 0.2 0.049 13.2 0.2 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Methyltransf_32 PF13679.6 PXF39533.1 - 2.3e-07 30.9 0.0 4.1e-07 30.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF39533.1 - 3e-06 27.1 0.0 6.9e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF39533.1 - 1.6e-05 25.5 0.2 5.1e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 PXF39533.1 - 0.00046 19.7 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 PXF39533.1 - 0.00065 20.4 0.0 0.0013 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF39533.1 - 0.0012 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 PXF39533.1 - 0.0025 17.2 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PXF39533.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PXF39533.1 - 0.0043 17.7 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 PXF39533.1 - 0.0044 16.2 0.0 0.0051 15.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin Methyltransf_23 PF13489.6 PXF39533.1 - 0.058 13.2 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 PXF39533.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Pkinase PF00069.25 PXF39534.1 - 3.5e-22 79.0 0.0 3.7e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF39534.1 - 3.6e-09 36.3 0.0 3.9e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF39534.1 - 0.00021 20.2 0.0 0.00024 20.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF39534.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_18 PF13238.6 PXF39534.1 - 0.041 14.4 0.0 0.054 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Kinase-like PF14531.6 PXF39534.1 - 0.056 12.8 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 PXF39534.1 - 0.19 11.3 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 PXF39534.1 - 0.21 10.5 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF676 PF05057.14 PXF39535.1 - 5.7e-20 71.8 0.1 8.3e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PXF39535.1 - 0.0017 18.3 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cupin_1 PF00190.22 PXF39537.1 - 6.9e-07 29.0 0.1 1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF39537.1 - 0.00014 21.5 0.0 0.00063 19.4 0.0 1.9 1 1 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 PXF39537.1 - 0.056 13.3 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase Actin PF00022.19 PXF39538.1 - 9e-108 360.5 0.0 3.4e-107 358.6 0.0 1.7 1 1 0 1 1 1 1 Actin IBN_N PF03810.19 PXF39539.1 - 0.00094 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PXF39539.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 2 0 0 2 2 2 0 Exportin 1-like protein Chlorosome_CsmC PF11098.8 PXF39539.1 - 0.15 12.0 1.2 0.23 11.5 0.3 1.7 2 0 0 2 2 2 0 Chlorosome envelope protein C KxDL PF10241.9 PXF39542.1 - 0.096 13.0 3.8 0.23 11.8 3.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF5094 PF17015.5 PXF39542.1 - 0.29 11.2 7.1 0.37 10.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) FAM76 PF16046.5 PXF39542.1 - 1.7 7.9 12.5 2.2 7.6 12.5 1.2 1 0 0 1 1 1 0 FAM76 protein THOC7 PF05615.13 PXF39548.1 - 0.00027 21.2 1.5 0.0003 21.1 1.5 1.1 1 0 0 1 1 1 1 Tho complex subunit 7 Chibby PF14645.6 PXF39548.1 - 0.00033 21.0 0.1 0.00048 20.5 0.0 1.2 1 1 0 1 1 1 1 Chibby family HALZ PF02183.18 PXF39548.1 - 0.00086 19.5 1.5 0.0015 18.7 0.5 1.9 1 1 1 2 2 2 1 Homeobox associated leucine zipper ZapB PF06005.12 PXF39548.1 - 0.001 19.4 3.4 0.0013 19.1 3.4 1.3 1 0 0 1 1 1 1 Cell division protein ZapB JIP_LZII PF16471.5 PXF39548.1 - 0.0035 17.5 1.2 0.0052 16.9 1.1 1.3 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PXF39548.1 - 0.0068 16.5 2.2 0.011 15.8 2.2 1.4 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 PXF39548.1 - 0.0093 16.6 0.5 0.011 16.4 0.5 1.1 1 0 0 1 1 1 1 Initiation control protein YabA DUF1664 PF07889.12 PXF39548.1 - 0.0096 16.0 0.3 0.011 15.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) APC_N_CC PF16689.5 PXF39548.1 - 0.0098 15.9 0.6 0.015 15.4 0.6 1.4 1 1 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain DUF1843 PF08898.10 PXF39548.1 - 0.011 16.3 2.8 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) JAKMIP_CC3 PF16034.5 PXF39548.1 - 0.017 15.1 0.2 0.019 15.0 0.2 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain TSC22 PF01166.18 PXF39548.1 - 0.028 14.7 0.6 0.037 14.3 0.6 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 PXF39548.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.0 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIVA PF05103.13 PXF39548.1 - 0.039 14.1 2.4 0.047 13.8 2.4 1.1 1 0 0 1 1 1 0 DivIVA protein TMF_DNA_bd PF12329.8 PXF39548.1 - 0.039 14.0 4.5 0.047 13.7 4.5 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_23 PF13476.6 PXF39548.1 - 0.049 14.1 0.7 0.049 14.1 0.7 1.0 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 PXF39548.1 - 0.061 13.7 2.3 0.079 13.3 2.3 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF2205 PF10224.9 PXF39548.1 - 0.065 13.2 5.3 0.11 12.5 0.2 2.0 1 1 1 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 PXF39548.1 - 0.11 12.3 5.0 0.27 11.0 5.0 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 PXF39548.1 - 0.13 12.4 3.9 0.19 11.8 3.9 1.5 1 1 0 1 1 1 0 Basic region leucine zipper Sas6_CC PF18594.1 PXF39548.1 - 0.14 12.0 0.8 0.3 10.9 0.5 1.7 1 1 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Halo_GVPC PF05465.13 PXF39548.1 - 0.18 12.1 0.9 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Ribosomal_L7Ae PF01248.26 PXF39549.1 - 1.3e-24 85.7 0.0 1.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpecificRecomb PF10136.9 PXF39551.1 - 0.022 13.1 0.1 0.031 12.6 0.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase T3SS_ATPase_C PF18269.1 PXF39551.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain DUF4836 PF16120.5 PXF39553.1 - 0.075 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4836) Pkinase PF00069.25 PXF39555.1 - 2.4e-12 46.8 0.0 3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF39555.1 - 1.4e-06 28.4 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF39555.1 - 1.5e-05 24.5 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF39555.1 - 0.00031 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF39555.1 - 0.00055 19.6 0.2 0.0011 18.6 0.1 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF39555.1 - 0.0014 17.5 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF39555.1 - 0.17 11.2 0.0 0.35 10.1 0.0 1.4 2 0 0 2 2 2 0 Kinase-like DUF4836 PF16120.5 PXF39558.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4836) QueF PF14489.6 PXF39560.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Hva1_TUDOR PF11160.8 PXF39560.1 - 0.09 13.0 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain Pkinase PF00069.25 PXF39562.1 - 7.7e-12 45.1 0.0 9.7e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF39562.1 - 9.9e-07 28.9 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF39562.1 - 5.4e-06 25.9 0.0 7.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF39562.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF39562.1 - 0.00042 20.0 0.1 0.00086 19.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF39562.1 - 0.0013 17.6 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase T3SS_ATPase_C PF18269.1 PXF39566.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Cupin_1 PF00190.22 PXF39567.1 - 0.00039 20.0 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 PXF39568.1 - 2.9e-05 23.7 0.0 4.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cyclin_N PF00134.23 PXF39569.1 - 1.9e-35 121.4 1.0 2.7e-35 120.9 1.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain UPF0258 PF06789.12 PXF39569.1 - 0.097 12.8 0.8 0.28 11.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Uma2 PF05685.12 PXF39571.1 - 2.7e-07 30.3 0.3 6.4e-07 29.1 0.3 1.8 1 1 0 1 1 1 1 Putative restriction endonuclease Borrelia_P83 PF05262.11 PXF39571.1 - 0.045 12.2 41.0 0.058 11.9 41.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Raftlin PF15250.6 PXF39571.1 - 4 6.1 27.1 6.5 5.4 27.1 1.3 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 PXF39571.1 - 6.8 4.9 44.1 10 4.3 44.1 1.1 1 0 0 1 1 1 0 CDC45-like protein VWA PF00092.28 PXF39576.1 - 4.7e-17 62.8 0.0 6.5e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39576.1 - 1.1e-06 29.2 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF39576.1 - 0.066 12.4 0.0 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) HEPN_MAE_28990 PF18737.1 PXF39576.1 - 0.11 12.4 0.0 9 6.2 0.0 2.2 2 0 0 2 2 2 0 MAE_28990/MAE_18760-like HEPN Glyco_hydro_16 PF00722.21 PXF39577.1 - 1.7e-11 43.9 2.3 3.7e-11 42.8 1.9 1.6 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Imm64 PF15600.6 PXF39577.1 - 0.029 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 64 Glutaredoxin2_C PF04399.13 PXF39578.1 - 3e-23 82.1 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Transposase_21 PF02992.14 PXF39579.1 - 9.7e-15 54.4 0.4 9.4e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 PXF39579.1 - 0.093 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) PTH2 PF01981.16 PXF39580.1 - 1.9e-14 53.9 0.0 2.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3552 PF12072.8 PXF39581.1 - 9.4e-05 21.9 6.6 0.0046 16.4 1.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) Atg14 PF10186.9 PXF39581.1 - 0.001 18.2 9.0 0.019 14.1 3.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 PXF39581.1 - 0.0025 17.2 8.8 0.0036 16.7 8.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HALZ PF02183.18 PXF39581.1 - 0.027 14.7 1.0 3.4 7.9 0.2 2.9 2 2 0 2 2 2 0 Homeobox associated leucine zipper LURAP PF14854.6 PXF39581.1 - 0.12 12.3 0.4 13 5.8 0.0 2.5 2 1 0 2 2 2 0 Leucine rich adaptor protein TPR_MLP1_2 PF07926.12 PXF39581.1 - 0.23 11.5 5.4 0.48 10.5 0.9 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PXF39581.1 - 0.35 10.1 4.8 0.27 10.5 1.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.11 PXF39581.1 - 0.39 10.7 6.7 1 9.4 0.6 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4200 PF13863.6 PXF39581.1 - 0.7 10.3 3.8 8.2 6.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 PXF39581.1 - 1 8.2 2.4 2.5 6.9 2.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 PXF39581.1 - 1.3 9.3 5.0 15 5.9 2.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 PXF39581.1 - 3.5 7.4 7.0 10 5.9 0.6 2.5 2 1 0 2 2 2 0 Septum formation initiator tRNA_bind PF01588.20 PXF39584.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain WD40 PF00400.32 PXF39587.1 - 1.8e-27 95.0 15.3 2.3e-08 34.6 0.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat NB-ARC PF00931.22 PXF39587.1 - 1.3e-13 50.8 0.0 2.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF39587.1 - 1.7e-06 28.2 2.6 1.3 9.4 0.1 5.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Jnk-SapK_ap_N PF09744.9 PXF39587.1 - 0.0027 18.0 1.3 0.0076 16.5 1.3 1.8 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 AAA_22 PF13401.6 PXF39587.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF4988 PF16378.5 PXF39587.1 - 0.043 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function IKI3 PF04762.12 PXF39587.1 - 0.05 11.6 0.0 0.092 10.7 0.0 1.4 1 0 0 1 1 1 0 IKI3 family DUF727 PF05303.12 PXF39587.1 - 0.051 13.6 0.1 54 3.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF727) Glyco_transf_34 PF05637.12 PXF39588.1 - 0.15 11.7 0.9 0.6 9.8 0.2 1.8 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF996 PF06195.13 PXF39588.1 - 0.16 12.3 1.9 0.42 10.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) MRAP PF15183.6 PXF39588.1 - 4.8 7.2 5.3 18 5.3 1.3 2.7 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF4199 PF13858.6 PXF39588.1 - 7.9 6.8 8.0 0.82 10.0 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Nop14 PF04147.12 PXF39589.1 - 4.2e-87 293.3 48.2 1.7e-48 165.6 38.7 3.1 2 1 1 3 3 3 3 Nop14-like family Myc-LZ PF02344.15 PXF39589.1 - 0.91 9.7 7.8 2.9 8.1 7.8 2.0 1 0 0 1 1 1 0 Myc leucine zipper domain Nanovirus_C8 PF05629.11 PXF39590.1 - 0.04 14.0 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Nanovirus component 8 (C8) protein ABC_ATPase PF09818.9 PXF39593.1 - 1.7e-22 79.8 0.0 1.8e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Brr6_like_C_C PF10104.9 PXF39595.1 - 0.066 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain IMUP PF15761.5 PXF39595.1 - 2.2 9.0 21.0 0.21 12.3 14.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Macoilin PF09726.9 PXF39595.1 - 6.9 5.1 10.2 9.1 4.7 10.2 1.3 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 PXF39596.1 - 2.1e-30 105.9 0.0 3.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PXF39596.1 - 1.3e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF39596.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CaKB PF03185.15 PXF39597.1 - 0.068 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit DnaJ PF00226.31 PXF39600.1 - 0.0086 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1380 PF07128.12 PXF39603.1 - 0.039 14.1 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) 5_3_exonuc PF01367.20 PXF39607.1 - 0.097 13.3 0.2 0.12 13.0 0.2 1.3 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Uma2 PF05685.12 PXF39610.1 - 0.00058 19.4 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Glyco_transf_34 PF05637.12 PXF39611.1 - 0.15 11.7 0.9 0.6 9.8 0.2 1.8 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF996 PF06195.13 PXF39611.1 - 0.16 12.3 1.9 0.42 10.9 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF996) MRAP PF15183.6 PXF39611.1 - 4.8 7.2 5.3 18 5.3 1.3 2.7 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF4199 PF13858.6 PXF39611.1 - 7.9 6.8 8.0 0.82 10.0 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Nop14 PF04147.12 PXF39612.1 - 4.5e-87 293.2 48.5 1.7e-48 165.6 38.7 3.1 2 1 1 3 3 3 3 Nop14-like family Myc-LZ PF02344.15 PXF39612.1 - 0.91 9.7 7.8 2.9 8.1 7.8 2.0 1 0 0 1 1 1 0 Myc leucine zipper domain An_peroxidase PF03098.15 PXF39614.1 - 1.6e-115 386.7 0.1 1.9e-115 386.5 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF39615.1 - 2e-81 274.2 0.0 2.5e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Prion_bPrPp PF11587.8 PXF39616.1 - 1.2 9.0 3.1 2 8.3 3.1 1.3 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal DUF1811 PF08838.10 PXF39617.1 - 0.0044 17.2 1.1 0.0061 16.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1811) MbeD_MobD PF04899.12 PXF39617.1 - 0.0052 16.9 1.2 0.01 16.0 0.5 1.9 1 1 1 2 2 2 1 MbeD/MobD like Spc24 PF08286.11 PXF39617.1 - 0.46 10.7 3.6 0.61 10.4 3.6 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 WD40 PF00400.32 PXF39618.1 - 4.1e-12 46.4 7.9 0.0033 18.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF39618.1 - 0.012 15.9 0.0 2.8 8.3 0.0 3.9 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain potato_inhibit PF00280.18 PXF39618.1 - 0.089 13.5 0.2 14 6.4 0.0 3.4 4 0 0 4 4 4 0 Potato inhibitor I family DUF4549 PF15082.6 PXF39618.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) KCNQ2_u3 PF16642.5 PXF39619.1 - 1.4 9.9 5.2 1.2 10.1 1.7 2.5 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 SBBP PF06739.11 PXF39620.1 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 Beta-propeller repeat DUF3402 PF11882.8 PXF39620.1 - 0.47 9.5 2.7 0.29 10.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) PRCC PF10253.9 PXF39620.1 - 3 8.6 5.3 1.3 9.8 2.6 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Nab2 PF11517.8 PXF39621.1 - 0.027 14.8 0.4 0.045 14.0 0.4 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RVT_1 PF00078.27 PXF39626.1 - 8.6e-32 110.4 0.0 1.5e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PXF39626.1 - 1.3e-12 47.6 0.0 5.5e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF39626.1 - 6.4e-05 22.6 0.0 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NdhN PF11909.8 PXF39626.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Gate PF07670.14 PXF39626.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoside recognition DTHCT PF08070.11 PXF39627.1 - 0.016 15.9 6.7 0.034 14.9 6.7 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF2477 PF10631.9 PXF39627.1 - 0.17 12.6 11.4 1.5 9.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2477) Peptidase_C48 PF02902.19 PXF39628.1 - 0.00064 19.6 1.8 0.0012 18.8 1.8 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF676 PF05057.14 PXF39631.1 - 2.9e-12 46.6 0.1 4.2e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Kelch_6 PF13964.6 PXF39634.1 - 5.8e-22 77.2 15.1 0.00039 20.6 0.3 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PXF39634.1 - 1.1e-13 51.0 19.8 0.0017 18.4 0.2 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PXF39634.1 - 3.7e-12 45.6 33.7 2e-05 24.0 1.1 7.5 7 2 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 PXF39634.1 - 3.4e-11 42.7 16.2 0.0066 16.4 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PXF39634.1 - 1.9e-07 30.9 16.0 0.017 15.1 0.2 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PXF39634.1 - 3.1e-07 30.5 42.0 0.00044 20.5 0.2 7.2 8 1 0 8 8 8 4 Galactose oxidase, central domain PRCC PF10253.9 PXF39634.1 - 0.66 10.7 9.6 1.2 9.8 9.6 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_A17 PF05380.13 PXF39635.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase AHSP PF09236.10 PXF39639.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF726 PF05277.12 PXF39643.1 - 1.2e-51 175.7 0.0 1.7e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) HSP70 PF00012.20 PXF39643.1 - 0.0026 16.1 0.6 0.0041 15.4 0.6 1.2 1 0 0 1 1 1 1 Hsp70 protein DUF900 PF05990.12 PXF39643.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF726 PF05277.12 PXF39644.1 - 2e-07 30.3 7.3 3e-07 29.7 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) KdpC PF02669.15 PXF39644.1 - 0.017 14.9 0.6 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 K+-transporting ATPase, c chain REV PF00424.18 PXF39644.1 - 0.044 13.8 0.3 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Phage_holin_3_6 PF07332.11 PXF39644.1 - 0.44 10.6 7.7 0.069 13.2 3.8 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SR-25 PF10500.9 PXF39644.1 - 0.52 9.9 12.4 0.8 9.3 4.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DDRGK PF09756.9 PXF39645.1 - 2.5 7.7 16.1 4 7.0 16.1 1.3 1 0 0 1 1 1 0 DDRGK domain CNOT1_TTP_bind PF16417.5 PXF39647.1 - 1.2e-05 24.6 0.0 3.1e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 PXF39647.1 - 0.00057 20.0 0.2 0.00087 19.4 0.2 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 PXF39648.1 - 2.3e-70 236.5 4.3 3.5e-70 235.9 4.0 1.4 1 1 1 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PXF39649.1 - 7.8e-26 90.8 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) RVT_1 PF00078.27 PXF39650.1 - 2.1e-30 105.9 0.0 3.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PXF39650.1 - 1.3e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF39650.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ELFV_dehydrog PF00208.21 PXF39652.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase BRCT PF00533.26 PXF39659.1 - 4e-06 27.1 0.0 7.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Glycoprotein PF03409.15 PXF39660.1 - 0.034 13.0 0.2 0.047 12.5 0.2 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Methyltransf_31 PF13847.6 PXF39661.1 - 5.2e-12 45.8 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF39661.1 - 1.2e-10 42.0 0.0 2.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF39661.1 - 6.1e-09 36.4 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF39661.1 - 2.1e-07 31.0 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF39661.1 - 9.4e-07 29.5 0.0 1.7e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF39661.1 - 5.5e-05 23.1 0.0 7.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 PXF39661.1 - 0.00024 20.7 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 PXF39661.1 - 0.00032 20.1 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PXF39661.1 - 0.00054 19.8 0.0 0.00081 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 PXF39661.1 - 0.0015 17.7 0.1 0.0022 17.2 0.1 1.3 1 1 0 1 1 1 1 Fibrillarin MTS PF05175.14 PXF39661.1 - 0.0025 17.4 0.0 0.007 15.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 PXF39661.1 - 0.052 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CheR PF01739.18 PXF39661.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pkinase PF00069.25 PXF39662.1 - 3.6e-31 108.5 0.0 4.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF39662.1 - 2e-16 60.1 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF39662.1 - 0.0018 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF39662.1 - 0.0062 15.9 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Morc6_S5 PF17942.1 PXF39662.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like Transposase_21 PF02992.14 PXF39664.1 - 3.1e-15 56.0 0.5 3e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 PXF39664.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Adeno_VII PF03228.14 PXF39665.1 - 0.013 16.1 0.2 0.034 14.8 0.1 1.6 1 1 1 2 2 2 0 Adenoviral core protein VII Fzo_mitofusin PF04799.13 PXF39665.1 - 0.051 13.1 1.7 0.075 12.6 1.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region Trimer_CC PF08954.11 PXF39665.1 - 0.36 10.4 5.3 2.5 7.7 0.7 3.1 1 1 2 3 3 3 0 Trimerisation motif ParB PF08775.10 PXF39665.1 - 0.37 11.3 4.4 0.47 10.9 4.0 1.4 1 1 0 1 1 1 0 ParB family dCMP_cyt_deam_1 PF00383.23 PXF39667.1 - 1.3e-23 82.8 0.2 1.7e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF39667.1 - 5.4e-19 68.3 0.0 6.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 PXF39667.1 - 0.001 19.2 0.3 0.0015 18.6 0.3 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 PXF39667.1 - 0.044 13.8 0.2 0.064 13.3 0.2 1.2 1 0 0 1 1 1 0 APOBEC2 WD40 PF00400.32 PXF39669.1 - 4.2e-79 258.4 45.5 2e-08 34.7 0.6 11.0 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF39669.1 - 1.5e-14 54.1 18.2 0.1 12.9 0.1 9.8 1 1 9 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF39669.1 - 1.2e-13 50.9 0.0 2.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ChapFlgA PF13144.6 PXF39669.1 - 7.9e-11 42.1 13.7 6.7 6.8 0.0 8.8 7 2 2 9 9 9 5 Chaperone for flagella basal body P-ring formation DUF727 PF05303.12 PXF39669.1 - 2.5e-06 27.5 2.6 88 3.2 0.0 7.8 8 0 0 8 8 8 0 Protein of unknown function (DUF727) PD40 PF07676.12 PXF39669.1 - 1.3e-05 25.0 0.0 1.9e+02 2.1 0.0 8.8 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 PXF39669.1 - 2.7e-05 23.3 10.5 14 4.5 0.1 8.5 1 1 9 11 11 11 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 PXF39669.1 - 0.00073 19.5 0.2 11 6.1 0.0 6.5 10 0 0 10 10 9 1 Ciliary BBSome complex subunit 2, middle region Jnk-SapK_ap_N PF09744.9 PXF39669.1 - 0.0039 17.4 1.3 0.01 16.1 1.3 1.7 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 AAA_22 PF13401.6 PXF39669.1 - 0.0087 16.3 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IKI3 PF04762.12 PXF39669.1 - 0.091 10.7 0.0 0.21 9.5 0.0 1.6 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.6 PXF39669.1 - 0.88 10.2 16.7 68 4.1 0.0 8.0 5 3 5 10 10 8 0 PQQ-like domain Nup160 PF11715.8 PXF39669.1 - 3.4 6.2 27.7 8.3 4.9 0.0 8.2 8 2 2 10 10 10 0 Nucleoporin Nup120/160 DUF726 PF05277.12 PXF39670.1 - 1.6e-70 237.7 3.9 1.3e-56 192.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Sel1 PF08238.12 PXF39671.1 - 1.5e-06 28.6 5.1 0.42 11.4 0.2 6.3 7 0 0 7 7 7 3 Sel1 repeat TPR_19 PF14559.6 PXF39671.1 - 0.0069 16.9 0.9 30 5.2 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF39671.1 - 0.046 14.4 0.6 8.4 7.3 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 PXF39671.1 - 0.1 12.9 0.1 10 6.6 0.0 3.9 4 0 0 4 4 4 0 PPR repeat RVT_1 PF00078.27 PXF39673.1 - 7.8e-13 48.5 0.0 5.5e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PXF39675.1 - 4.5e-18 65.3 0.4 7.2e-18 64.6 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Rtf2 PF04641.12 PXF39675.1 - 0.037 13.4 3.6 0.063 12.6 3.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Geminin PF07412.12 PXF39686.1 - 0.067 12.9 0.1 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Geminin zf-B_box PF00643.24 PXF39689.1 - 2.8e-06 27.4 2.6 2.8e-06 27.4 2.6 2.1 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 PXF39689.1 - 0.0054 16.9 2.0 0.015 15.5 2.0 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Retrotran_gag_3 PF14244.6 PXF39691.1 - 0.011 15.6 0.9 2.3e+02 1.7 0.0 5.0 5 0 0 5 5 5 0 gag-polypeptide of LTR copia-type RPE65 PF03055.15 PXF39693.1 - 2.8e-16 59.8 0.0 3e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RETICULATA-like PF11891.8 PXF39694.1 - 4.8e-15 55.8 0.1 6.3e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related FKBP_C PF00254.28 PXF39695.1 - 3.4e-09 36.9 0.1 7.5e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Arm_vescicular PF18770.1 PXF39696.1 - 0.92 9.5 5.2 1.5 8.8 0.2 2.6 2 0 0 2 2 2 0 Armadillo tether-repeat of vescicular transport factor HEAT_2 PF13646.6 PXF39697.1 - 0.00013 22.3 1.2 0.00017 21.9 1.2 1.1 1 0 0 1 1 1 1 HEAT repeats Rad51 PF08423.11 PXF39697.1 - 0.0023 17.2 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 PAXNEB PF05625.11 PXF39697.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein WBS28 PF15164.6 PXF39698.1 - 0.17 11.1 0.2 0.28 10.4 0.2 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue tRNA-synt_1e PF01406.19 PXF39699.1 - 4.9e-100 334.8 0.0 7.6e-100 334.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PXF39699.1 - 5.4e-11 41.9 0.0 8.3e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF39699.1 - 0.00073 17.9 0.0 0.0053 15.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 PXF39699.1 - 0.044 12.7 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 PXF39699.1 - 0.044 14.3 0.2 0.044 14.3 0.2 2.0 2 1 0 2 2 2 0 DALR domain Coatomer_E PF04733.14 PXF39700.1 - 1.3e-80 270.9 1.5 1.5e-80 270.8 1.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 PXF39700.1 - 6.7e-10 38.3 0.0 0.0034 17.4 0.0 4.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF39700.1 - 1.3e-08 34.3 0.6 0.0014 18.4 0.0 3.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF39700.1 - 1.3e-08 35.2 0.2 7.2e-05 23.2 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF39700.1 - 1.8e-07 31.4 0.2 0.6 11.1 0.0 5.5 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF39700.1 - 2.7e-07 30.8 0.2 0.001 19.3 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF39700.1 - 7.6e-07 28.7 1.4 0.12 12.4 0.0 4.3 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF39700.1 - 0.00056 20.4 0.0 6.3 7.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF39700.1 - 0.00063 19.9 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PXF39700.1 - 0.00065 19.7 0.0 7.5 7.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 PXF39700.1 - 0.00093 19.6 0.0 0.26 12.0 0.0 3.4 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF39700.1 - 0.0057 17.3 0.0 0.23 12.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ank_2 PF12796.7 PXF39702.1 - 9.2e-20 71.0 0.4 1.2e-12 48.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ACBP PF00887.19 PXF39702.1 - 2.1e-19 69.5 0.0 3.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 PXF39702.1 - 1.4e-15 57.1 3.3 3.6e-09 36.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PXF39702.1 - 1.8e-14 53.4 0.3 1.5e-05 25.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PXF39702.1 - 1.7e-11 44.4 0.3 1.3e-08 35.2 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF39702.1 - 1.1e-06 28.5 0.3 0.016 15.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 PXF39703.1 - 3.1e-07 30.2 14.5 5e-07 29.5 14.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF39703.1 - 6.6e-07 29.6 18.5 1.1e-06 28.8 18.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PXF39703.1 - 1.3e-06 28.1 14.7 2.3e-06 27.4 14.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PXF39703.1 - 8.3e-06 25.5 16.8 1.4e-05 24.8 16.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF39703.1 - 2.3e-05 24.2 16.1 3.6e-05 23.5 16.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.14 PXF39703.1 - 5.1e-05 23.0 3.0 5.1e-05 23.0 3.0 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 PXF39703.1 - 0.0001 22.2 15.6 0.00021 21.2 15.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF39703.1 - 0.00098 19.1 10.4 0.00098 19.1 10.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF39703.1 - 0.0018 18.5 17.6 0.0034 17.6 17.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PXF39703.1 - 0.0024 18.0 13.8 0.0054 16.9 13.9 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 PXF39703.1 - 0.075 13.1 7.9 0.13 12.3 7.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Methyltransf_31 PF13847.6 PXF39705.1 - 2.6e-17 63.0 0.0 6.1e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF39705.1 - 1.7e-15 57.5 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF39705.1 - 1.6e-14 54.4 0.0 2.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF39705.1 - 1.2e-13 51.2 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF39705.1 - 1.7e-11 44.6 0.0 5.9e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF39705.1 - 3.5e-08 33.1 0.1 5.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PXF39705.1 - 5.1e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PXF39705.1 - 1.1e-05 25.0 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 PXF39705.1 - 2.2e-05 23.9 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 PXF39705.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PXF39705.1 - 0.00084 18.8 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 PXF39705.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 PXF39705.1 - 0.013 16.5 0.0 0.03 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 PXF39705.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 PXF39705.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Dimerisation2 PF16864.5 PXF39705.1 - 0.11 12.4 0.0 3.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Dimerisation domain HTH_29 PF13551.6 PXF39705.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix GDP_Man_Dehyd PF16363.5 PXF39706.1 - 2.7e-68 230.8 0.0 3.1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF39706.1 - 7.9e-52 176.1 0.1 1e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PXF39706.1 - 2.3e-18 66.3 0.1 2.5e-17 62.9 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 PXF39706.1 - 2.8e-17 62.8 0.0 1.1e-16 60.8 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PXF39706.1 - 3.3e-17 62.5 0.0 4.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PXF39706.1 - 6.4e-17 61.5 0.0 9e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF39706.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RVT_2 PF07727.14 PXF39708.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A17 PF05380.13 PXF39709.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase Ubie_methyltran PF01209.18 PXF39710.1 - 4.4e-05 22.9 0.0 0.00017 21.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Transposase_21 PF02992.14 PXF39711.1 - 2.8e-14 52.9 0.6 2.3e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 PXF39711.1 - 0.098 12.3 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) TPR_2 PF07719.17 PXF39715.1 - 5e-10 38.7 0.1 0.053 13.7 0.0 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF39715.1 - 2.2e-08 34.6 0.2 3.5e-06 27.6 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF39715.1 - 5.6e-07 30.0 0.0 0.00023 21.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF39715.1 - 7.1e-06 26.1 0.0 5.3e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF39715.1 - 2.3e-05 24.2 0.0 0.089 13.0 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF39715.1 - 3.1e-05 23.6 1.1 0.017 14.9 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF39715.1 - 3.5e-05 24.0 1.5 0.68 10.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF39715.1 - 6.3e-05 22.6 0.0 0.075 12.7 0.0 3.4 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 PXF39715.1 - 0.00017 22.1 0.1 0.53 11.2 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF39715.1 - 0.00031 20.5 0.1 1.5 9.0 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF39715.1 - 0.032 14.1 0.3 0.76 9.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PXF39715.1 - 0.047 13.9 0.0 1.5 9.0 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF39715.1 - 0.13 12.5 0.1 0.57 10.4 0.0 2.1 2 1 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CNOT1_CAF1_bind PF16415.5 PXF39716.1 - 1.6e-06 27.7 0.1 2.1e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain PCNA_N PF00705.18 PXF39716.1 - 0.056 13.2 0.2 0.077 12.7 0.2 1.1 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain CNOT1_TTP_bind PF16417.5 PXF39717.1 - 2.1e-39 134.6 0.0 2.6e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3652 PF12372.8 PXF39717.1 - 0.11 12.4 0.5 14 5.6 0.1 2.4 2 0 0 2 2 2 0 Huntingtin protein region VWA PF00092.28 PXF39720.1 - 3.7e-17 63.1 0.0 4.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39720.1 - 7.6e-07 29.8 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF39720.1 - 0.00058 19.1 0.0 0.0044 16.2 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) VWA PF00092.28 PXF39721.1 - 2.8e-11 44.0 0.1 3.4e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39721.1 - 2.2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Sel1 PF08238.12 PXF39723.1 - 1.7e-17 63.4 0.2 0.00078 20.0 0.0 8.0 9 0 0 9 9 9 4 Sel1 repeat TPR_6 PF13174.6 PXF39723.1 - 0.00089 19.7 0.1 22 6.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF39723.1 - 0.015 15.6 9.3 2.4 8.5 0.2 5.7 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF39723.1 - 0.048 14.5 15.1 14 6.8 0.1 7.1 7 3 1 8 8 8 0 Tetratricopeptide repeat RVT_2 PF07727.14 PXF39726.1 - 6.1e-30 104.6 0.0 7.1e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EcKinase PF02958.20 PXF39730.1 - 2.4e-07 30.4 0.0 0.0014 18.0 0.0 2.7 3 0 0 3 3 3 2 Ecdysteroid kinase APH PF01636.23 PXF39730.1 - 1.6e-06 28.2 0.1 1.1e-05 25.5 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PMM PF03332.13 PXF39733.1 - 1.4e-52 178.6 0.1 1.6e-52 178.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PXF39733.1 - 9.9e-05 22.2 0.0 0.00011 22.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF39733.1 - 0.001 18.7 0.0 0.0012 18.4 0.0 1.0 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Uma2 PF05685.12 PXF39734.1 - 2.7e-11 43.3 0.3 1.9e-09 37.3 0.3 2.3 1 1 0 1 1 1 1 Putative restriction endonuclease DUF4597 PF15366.6 PXF39734.1 - 1.5 8.7 5.2 0.77 9.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) ERM PF00769.19 PXF39734.1 - 5 6.9 41.8 6.8 6.4 41.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mannitol_dh PF01232.23 PXF39735.1 - 3.2e-38 131.3 0.0 3.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain HDAC4_Gln PF12203.8 PXF39738.1 - 0.026 14.7 2.2 0.026 14.7 2.2 2.0 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Mating_C PF12737.7 PXF39738.1 - 0.19 10.9 2.8 0.2 10.8 2.8 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 KfrA_N PF11740.8 PXF39739.1 - 0.018 15.7 1.3 0.025 15.3 1.3 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HDAC4_Gln PF12203.8 PXF39739.1 - 0.019 15.1 1.8 0.019 15.1 1.8 2.0 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 SEA PF01390.20 PXF39739.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 SEA domain Enkurin PF13864.6 PXF39741.1 - 0.035 14.5 1.3 0.052 14.0 1.3 1.3 1 0 0 1 1 1 0 Calmodulin-binding AnfO_nitrog PF09582.10 PXF39741.1 - 0.044 13.1 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) FERM_f0 PF16511.5 PXF39741.1 - 0.084 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM ASL_C PF08328.11 PXF39741.1 - 0.086 12.9 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Tap-RNA_bind PF09162.10 PXF39741.1 - 0.09 12.6 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Tap, RNA-binding VWA PF00092.28 PXF39744.1 - 2.6e-16 60.4 0.0 3.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39744.1 - 8.6e-06 26.4 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF39744.1 - 0.00057 19.2 0.0 0.0036 16.6 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) VWA PF00092.28 PXF39745.1 - 4e-09 36.9 0.0 4.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39745.1 - 4e-05 24.2 0.0 0.0001 22.9 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain NIR_SIR PF01077.22 PXF39747.1 - 9.7e-06 25.2 0.0 1.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain DUF755 PF05501.11 PXF39749.1 - 7.4e-05 23.0 4.2 0.00018 21.7 4.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Snapin_Pallidin PF14712.6 PXF39749.1 - 0.0067 16.8 2.4 0.038 14.4 2.2 2.0 1 1 1 2 2 2 1 Snapin/Pallidin SR-25 PF10500.9 PXF39749.1 - 0.012 15.2 12.8 0.02 14.5 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPV_P10 PF05531.12 PXF39749.1 - 0.2 12.2 4.0 0.22 12.0 0.6 2.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Homeobox_KN PF05920.11 PXF39750.1 - 2.7e-15 56.0 0.8 1.5e-14 53.6 0.2 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 PXF39750.1 - 1.7e-06 27.8 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PXF39750.1 - 0.074 12.5 0.8 0.22 11.0 0.8 1.8 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EzrA PF06160.12 PXF39751.1 - 0.011 13.9 1.2 0.016 13.4 1.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF39751.1 - 0.019 15.2 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF39751.1 - 9.8 6.9 13.8 1.7 9.3 6.8 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Ank_2 PF12796.7 PXF39754.1 - 5.2e-24 84.6 11.8 3.1e-13 50.1 2.8 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF39754.1 - 7.5e-16 58.0 7.4 7.2e-05 23.0 0.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PXF39754.1 - 1.5e-13 50.9 4.1 3.4e-05 24.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PXF39754.1 - 4.9e-13 48.9 3.1 0.0054 17.1 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 PXF39754.1 - 2e-12 46.1 2.5 0.00087 19.6 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 PXF39755.1 - 3.1e-83 274.4 51.8 2.7e-17 63.1 0.7 5.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF39755.1 - 8.6e-55 182.1 27.6 3.8e-09 36.6 0.1 10.1 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 PXF39755.1 - 3.4e-47 158.2 11.0 4.8e-07 30.2 0.0 7.9 3 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF39755.1 - 6e-47 152.2 5.3 0.00026 21.2 0.0 10.7 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.30 PXF39755.1 - 1.2e-44 148.9 24.6 0.00037 20.8 0.1 11.0 11 0 0 11 11 11 9 Ankyrin repeat 4HBT PF03061.22 PXF39755.1 - 0.011 16.0 1.8 0.12 12.8 0.2 3.5 5 1 1 6 6 4 0 Thioesterase superfamily ABC_cobalt PF09819.9 PXF39755.1 - 0.023 14.8 1.2 26 4.9 0.0 4.0 1 1 3 5 5 5 0 ABC-type cobalt transport system, permease component FLgD_tudor PF13861.6 PXF39755.1 - 0.061 13.6 0.0 12 6.2 0.1 2.9 2 2 0 2 2 2 0 FlgD Tudor-like domain GDPD PF03009.17 PXF39755.1 - 0.062 13.0 5.6 2.5 7.7 1.4 2.3 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family GrpE PF01025.19 PXF39755.1 - 0.091 12.4 0.3 2.1 8.0 0.1 2.6 1 1 0 2 2 2 0 GrpE AAA_assoc_C PF09821.9 PXF39755.1 - 0.14 12.7 3.9 51 4.4 0.0 4.0 2 2 2 4 4 4 0 C-terminal AAA-associated domain XisI PF08869.11 PXF39755.1 - 0.17 12.3 1.8 17 5.8 0.0 4.2 3 2 1 4 4 4 0 XisI protein DUF3107 PF11305.8 PXF39755.1 - 0.84 9.9 6.4 79 3.6 0.2 5.0 2 2 3 6 6 6 0 Protein of unknown function (DUF3107) DUF3223 PF11523.8 PXF39755.1 - 1.1 10.2 6.0 1e+02 3.8 0.1 4.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3223) PglD_N PF17836.1 PXF39755.1 - 1.9 9.2 10.7 27 5.5 0.0 6.3 8 0 0 8 8 8 0 PglD N-terminal domain CPP1-like PF11833.8 PXF39756.1 - 0.17 11.5 2.2 0.29 10.8 0.2 2.3 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FAA_hydro_N_2 PF18288.1 PXF39758.1 - 0.077 13.4 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Geminin PF07412.12 PXF39759.1 - 0.067 12.9 0.1 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Geminin QueF PF14489.6 PXF39760.1 - 0.021 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein Pkinase PF00069.25 PXF39762.1 - 7.1e-12 45.2 0.0 9.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF39762.1 - 1.5e-06 28.3 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF39762.1 - 5.1e-06 25.9 0.0 6.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF39762.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF39762.1 - 0.00043 19.9 0.1 0.00089 18.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF39762.1 - 0.00084 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ephrin PF00812.17 PXF39762.1 - 0.02 14.9 0.2 0.031 14.3 0.2 1.3 1 0 0 1 1 1 0 Ephrin Kinase-like PF14531.6 PXF39762.1 - 0.2 11.0 0.0 0.39 10.0 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Adeno_E3 PF06040.11 PXF39764.1 - 0.063 13.4 0.4 1.7 8.8 0.4 2.7 1 1 0 1 1 1 0 Adenovirus E3 protein QueF PF14489.6 PXF39767.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Hva1_TUDOR PF11160.8 PXF39767.1 - 0.09 13.0 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain Pkinase PF00069.25 PXF39769.1 - 8.4e-12 45.0 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF39769.1 - 1.1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF39769.1 - 5.9e-06 25.8 0.0 7.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF39769.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF39769.1 - 0.00046 19.8 0.1 0.00091 18.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF39769.1 - 0.0013 17.6 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF39769.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like ArsA_ATPase PF02374.15 PXF39773.1 - 0.054 12.7 1.8 0.11 11.6 0.0 1.9 1 1 1 2 2 2 0 Anion-transporting ATPase ArsA_ATPase PF02374.15 PXF39774.1 - 2.7e-12 46.5 0.2 2.9e-12 46.4 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase Dak1_2 PF13684.6 PXF39774.1 - 0.021 13.9 0.4 0.024 13.7 0.4 1.0 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Sel1 PF08238.12 PXF39775.1 - 3.2e-21 75.3 0.0 0.00016 22.2 0.0 5.3 5 0 0 5 5 5 4 Sel1 repeat TPR_14 PF13428.6 PXF39775.1 - 0.0019 18.9 10.8 1.4 9.9 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF39775.1 - 0.0044 17.3 0.0 20 5.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF39775.1 - 0.011 16.4 1.1 5.9 7.7 0.0 4.8 4 2 0 4 4 4 0 Tetratricopeptide repeat DUF5029 PF16432.5 PXF39776.1 - 0.037 13.6 0.1 0.043 13.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) APC_N_CC PF16689.5 PXF39777.1 - 0.029 14.4 2.3 0.06 13.4 2.3 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 PXF39777.1 - 0.041 14.1 2.4 0.31 11.3 0.3 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 SapC PF07277.11 PXF39777.1 - 0.057 13.0 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 SapC YabA PF06156.13 PXF39777.1 - 2 9.1 6.0 0.66 10.6 1.8 1.9 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 PXF39777.1 - 2.4 8.6 10.1 0.56 10.7 4.9 2.1 2 0 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 PXF39777.1 - 7.3 7.1 12.9 19 5.8 12.9 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 PXF39777.1 - 8.1 6.3 9.4 2 8.2 2.7 2.1 2 0 0 2 2 2 0 Septum formation initiator Nab2 PF11517.8 PXF39780.1 - 0.027 14.8 0.4 0.045 14.0 0.4 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PEMT PF04191.13 PXF39781.1 - 1.6e-08 34.9 0.0 2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 PXF39781.1 - 0.00019 21.8 0.0 0.00023 21.5 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.11 PXF39781.1 - 0.013 15.0 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 NnrU protein Uso1_p115_head PF04869.14 PXF39781.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Uma2 PF05685.12 PXF39782.1 - 0.0064 16.1 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 Putative restriction endonuclease XhlA PF10779.9 PXF39782.1 - 0.0065 16.6 1.0 0.013 15.6 1.0 1.5 1 0 0 1 1 1 1 Haemolysin XhlA AbrB-like PF14250.6 PXF39782.1 - 0.024 14.7 0.2 0.073 13.2 0.2 1.8 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Tropomyosin PF00261.20 PXF39782.1 - 0.025 13.9 9.8 0.36 10.2 2.3 2.2 1 1 1 2 2 2 0 Tropomyosin Alanine_zipper PF11839.8 PXF39782.1 - 0.44 11.0 13.9 0.93 9.9 13.9 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF4407 PF14362.6 PXF39782.1 - 1.6 8.0 6.5 2.4 7.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIP3 PF03915.13 PXF39789.1 - 0.0046 16.1 2.0 0.0072 15.5 2.0 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 PHM7_cyt PF14703.6 PXF39789.1 - 0.0073 16.6 0.1 0.0084 16.4 0.1 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter BLOC1_2 PF10046.9 PXF39789.1 - 0.013 15.7 1.9 0.013 15.7 1.9 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_7 PF01540.16 PXF39789.1 - 0.021 14.1 0.5 0.027 13.8 0.2 1.3 2 0 0 2 2 2 0 Adhesin lipoprotein RecG_N PF17190.4 PXF39789.1 - 0.056 14.2 1.3 0.056 14.2 1.3 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF4320 PF14208.6 PXF39789.1 - 0.15 12.2 1.0 0.22 11.6 0.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4320) Sel1 PF08238.12 PXF39790.1 - 0.011 16.4 0.0 0.31 11.8 0.0 2.5 3 0 0 3 3 3 0 Sel1 repeat DUF3880 PF12996.7 PXF39791.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) MscS_porin PF12795.7 PXF39792.1 - 0.00072 19.2 0.0 0.00078 19.1 0.0 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain HALZ PF02183.18 PXF39792.1 - 0.00074 19.7 0.4 0.001 19.2 0.4 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper APC_N_CC PF16689.5 PXF39792.1 - 0.0076 16.3 0.2 0.0099 15.9 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 PXF39792.1 - 0.0083 16.2 0.2 0.011 15.9 0.2 1.1 1 0 0 1 1 1 1 bZIP transcription factor ZapB PF06005.12 PXF39792.1 - 0.0092 16.4 0.1 0.0099 16.3 0.1 1.1 1 0 0 1 1 1 1 Cell division protein ZapB JIP_LZII PF16471.5 PXF39792.1 - 0.019 15.2 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 PXF39792.1 - 0.031 14.3 1.2 0.04 14.0 1.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Herpes_BLRF2 PF05812.12 PXF39792.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4618 PF15397.6 PXF39792.1 - 0.034 13.6 0.0 0.034 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DivIC PF04977.15 PXF39792.1 - 0.04 13.7 0.5 0.048 13.4 0.5 1.1 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 PXF39792.1 - 0.049 13.9 0.3 0.062 13.6 0.3 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 PXF39792.1 - 0.049 13.5 0.2 0.065 13.1 0.2 1.1 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC92 PF14916.6 PXF39792.1 - 0.067 13.0 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Sas6_CC PF18594.1 PXF39792.1 - 0.075 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain WD40_alt PF14077.6 PXF39792.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF4140 PF13600.6 PXF39792.1 - 0.14 12.6 0.1 0.16 12.4 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L7Ae PF01248.26 PXF39793.1 - 1.8e-07 30.8 0.5 0.00026 20.7 0.1 2.4 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fcf1 PF04900.12 PXF39793.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Fcf1 Toxin_38 PF14866.6 PXF39795.1 - 4.9e-06 26.7 17.3 3.2 8.1 0.1 5.3 5 0 0 5 5 5 5 Potassium channel toxin CagY_I PF14585.6 PXF39795.1 - 0.17 12.0 14.0 26 5.0 0.1 5.0 5 0 0 5 5 5 0 CagY type 1 repeat SBBP PF06739.11 PXF39796.1 - 0.0045 17.0 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-propeller repeat WD40 PF00400.32 PXF39798.1 - 1e-11 45.2 5.2 0.0033 18.2 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF39798.1 - 0.019 15.2 0.0 4.5 7.6 0.0 3.6 2 1 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain potato_inhibit PF00280.18 PXF39798.1 - 0.08 13.6 0.2 14 6.4 0.0 3.6 4 0 0 4 4 4 0 Potato inhibitor I family Spc24 PF08286.11 PXF39799.1 - 0.061 13.6 4.4 0.37 11.1 1.6 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 APC_N_CC PF16689.5 PXF39799.1 - 0.067 13.3 2.5 0.13 12.4 2.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain ZapB PF06005.12 PXF39799.1 - 3.8 8.0 9.8 0.87 10.1 5.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Ubie_methyltran PF01209.18 PXF39800.1 - 2e-05 24.0 0.0 9.4e-05 21.9 0.0 1.7 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Uma2 PF05685.12 PXF39801.1 - 3.4e-11 43.0 0.3 2.7e-09 36.8 0.3 2.3 1 1 0 1 1 1 1 Putative restriction endonuclease DUF4597 PF15366.6 PXF39801.1 - 1.5 8.6 5.2 0.85 9.4 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) ERM PF00769.19 PXF39801.1 - 5.8 6.6 41.7 8 6.2 41.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family WD40 PF00400.32 PXF39808.1 - 1.7e-78 256.5 45.7 3e-09 37.4 0.5 10.5 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF39808.1 - 5.2e-25 87.6 7.7 0.00065 19.9 0.0 8.8 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF39808.1 - 2e-18 66.5 17.0 0.05 12.5 0.0 8.9 2 1 7 9 9 9 8 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 PXF39808.1 - 1.8e-15 56.8 0.0 3.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF727 PF05303.12 PXF39808.1 - 2.6e-07 30.7 0.6 14 5.8 0.0 7.2 1 1 7 8 8 8 0 Protein of unknown function (DUF727) DUF374 PF04028.13 PXF39808.1 - 3.4e-06 26.5 2.8 14 5.3 0.0 6.2 2 1 4 6 6 6 0 Domain of unknown function (DUF374) APAF1_C PF17908.1 PXF39808.1 - 0.00038 20.5 1.4 0.0071 16.4 0.0 3.2 4 0 0 4 4 4 1 APAF-1 helical domain DUF3142 PF11340.8 PXF39808.1 - 0.0055 16.6 4.0 30 4.4 0.0 5.0 2 1 4 6 6 6 0 Protein of unknown function (DUF3142) DUF3313 PF11769.8 PXF39808.1 - 0.04 13.7 10.5 6.3 6.6 0.3 5.3 3 2 0 4 4 4 0 Protein of unknown function (DUF3313) UCH PF00443.29 PXF39808.1 - 0.042 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ParA PF10609.9 PXF39808.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase PQQ PF01011.21 PXF39808.1 - 0.09 12.7 0.2 1e+02 3.1 0.0 4.9 6 0 0 6 6 6 0 PQQ enzyme repeat CbiA PF01656.23 PXF39808.1 - 0.17 12.0 0.1 0.45 10.6 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SUKH-4 PF14435.6 PXF39808.1 - 1.2 9.2 23.3 14 5.7 0.1 7.6 1 1 4 8 8 8 0 SUKH-4 immunity protein Cu-oxidase_3 PF07732.15 PXF39809.1 - 6e-05 23.0 0.0 9.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase HTH_ABP1_N PF18107.1 PXF39810.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Cu-oxidase_3 PF07732.15 PXF39811.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.6 1 1 0 1 1 1 0 Multicopper oxidase Ribosomal_L7Ae PF01248.26 PXF39818.1 - 4.1e-27 93.7 0.7 6e-27 93.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fcf1 PF04900.12 PXF39818.1 - 0.056 13.8 0.0 0.095 13.1 0.0 1.4 1 0 0 1 1 1 0 Fcf1 THOC7 PF05615.13 PXF39819.1 - 0.002 18.4 1.3 0.0031 17.8 1.3 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 Chibby PF14645.6 PXF39819.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Chibby family ZapB PF06005.12 PXF39819.1 - 0.0082 16.6 3.3 0.011 16.1 3.3 1.3 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 PXF39819.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 1.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper JIP_LZII PF16471.5 PXF39819.1 - 0.022 14.9 0.8 0.035 14.3 0.8 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PXF39819.1 - 0.029 14.5 1.5 0.052 13.7 1.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor APC_N_CC PF16689.5 PXF39819.1 - 0.05 13.7 0.5 0.089 12.9 0.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1664 PF07889.12 PXF39819.1 - 0.084 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 PXF39819.1 - 0.12 13.0 0.5 0.12 13.0 0.5 1.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF1843 PF08898.10 PXF39819.1 - 0.44 11.1 3.7 7.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DivIC PF04977.15 PXF39819.1 - 0.46 10.3 3.7 0.9 9.4 3.7 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2205 PF10224.9 PXF39819.1 - 0.7 9.9 4.4 4.1 7.5 3.5 2.1 1 1 1 2 2 2 0 Short coiled-coil protein 2OG-FeII_Oxy PF03171.20 PXF39820.1 - 6.9e-05 23.3 0.0 0.00022 21.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 PXF39820.1 - 0.009 16.8 0.0 0.015 16.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal THOC2_N PF16134.5 PXF39820.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus APC1_C PF18122.1 PXF39821.1 - 7.2e-15 55.3 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain DUF3889 PF13028.6 PXF39821.1 - 0.032 14.2 0.0 0.93 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) PC_rep PF01851.22 PXF39822.1 - 0.00068 19.9 6.6 0.96 10.0 0.0 4.8 4 0 0 4 4 4 2 Proteasome/cyclosome repeat GTP_EFTU PF00009.27 PXF39823.1 - 3.8e-52 176.7 0.0 1.1e-51 175.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PXF39823.1 - 1.8e-17 63.2 0.0 5.5e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF39823.1 - 1.4e-12 47.8 3.3 3.7e-12 46.4 2.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PXF39823.1 - 1.1e-05 25.5 0.2 2.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PXF39823.1 - 8.8e-05 22.6 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_P_Rpp14 PF01900.19 PXF39824.1 - 1.1e-22 80.3 0.0 1.4e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family EF_TS PF00889.19 PXF39825.1 - 5.6e-46 156.8 0.1 1.3e-45 155.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor TS Myosin_tail_1 PF01576.19 PXF39825.1 - 0.099 10.4 0.1 0.13 10.0 0.1 1.1 1 0 0 1 1 1 0 Myosin tail PBS_linker_poly PF00427.21 PXF39827.1 - 2.3e-41 140.7 0.2 9.3e-41 138.8 0.0 2.0 2 0 0 2 2 2 1 Phycobilisome Linker polypeptide DUF4214 PF13946.6 PXF39827.1 - 0.078 13.0 0.1 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4214) adh_short_C2 PF13561.6 PXF39828.1 - 3.4e-66 223.2 2.9 4.6e-66 222.7 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PXF39828.1 - 4.6e-64 215.5 5.1 6.2e-64 215.1 5.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PXF39828.1 - 5.5e-20 72.0 3.4 7.7e-20 71.6 3.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF39828.1 - 0.0065 16.0 0.6 0.0094 15.4 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 PXF39828.1 - 0.011 15.1 0.8 0.025 13.9 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thioredoxin PF00085.20 PXF39829.1 - 5e-11 42.5 0.0 9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF39829.1 - 5.5e-05 23.6 0.0 0.00013 22.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PXF39829.1 - 0.0041 17.4 0.1 0.81 10.1 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 PXF39829.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like KORA PF16509.5 PXF39829.1 - 0.11 12.8 0.1 0.33 11.2 0.3 1.7 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Thioredoxin_4 PF13462.6 PXF39829.1 - 0.11 12.7 0.4 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Trehalose_PPase PF02358.16 PXF39830.1 - 9.1e-53 178.8 0.0 1.1e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 PXF39830.1 - 7.1e-07 29.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF39830.1 - 1.4e-05 24.8 0.0 9.3e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase RuvC PF02075.17 PXF39831.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Urb2 PF10441.9 PXF39831.1 - 0.77 9.6 0.0 0.77 9.6 0.0 4.4 6 0 0 6 6 6 0 Urb2/Npa2 family GAF_2 PF13185.6 PXF39832.1 - 0.00033 20.9 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 GAF domain HLH PF00010.26 PXF39832.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAF PF01590.26 PXF39832.1 - 0.022 15.4 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain Peptidase_A17 PF05380.13 PXF39833.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase Sel1 PF08238.12 PXF39834.1 - 1.2e-20 73.5 0.2 9.1e-05 23.0 0.0 5.3 5 0 0 5 5 5 4 Sel1 repeat TPR_14 PF13428.6 PXF39834.1 - 9.5e-06 26.0 8.6 1.4 9.9 0.1 5.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF39834.1 - 0.0014 18.9 0.0 20 5.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF39834.1 - 0.0024 18.4 2.1 6.5 7.6 0.0 5.4 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF39834.1 - 0.032 14.4 3.2 11 6.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Metallophos PF00149.28 PXF39835.1 - 1.4e-10 42.1 0.0 1.9e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF39835.1 - 2.8e-09 37.4 0.4 6.5e-09 36.2 0.0 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PXF39836.1 - 8.8e-08 32.9 0.0 1.5e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF39836.1 - 2.9e-07 30.8 0.1 6.2e-07 29.8 0.0 1.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain APH PF01636.23 PXF39840.1 - 2.1e-07 31.1 0.1 1.5e-06 28.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF39840.1 - 4.9e-05 22.8 0.0 0.024 13.9 0.0 2.7 3 0 0 3 3 3 2 Ecdysteroid kinase PsiF_repeat PF07769.14 PXF39841.1 - 4.4 7.3 5.8 36 4.4 0.1 3.6 4 0 0 4 4 4 0 psiF repeat Met_gamma_lyase PF06838.11 PXF39844.1 - 5.3e-33 114.1 0.1 6.3e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Met_gamma_lyase PF06838.11 PXF39845.1 - 5.6e-49 166.8 0.1 6.2e-49 166.6 0.1 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase YL1 PF05764.13 PXF39846.1 - 6.4e-19 69.0 24.2 8.5e-19 68.6 24.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein LPP PF04728.13 PXF39846.1 - 0.55 10.7 5.5 1.5 9.3 5.5 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Pkinase_fungal PF17667.1 PXF39846.1 - 1.2 7.9 5.3 1.6 7.5 5.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF1179 PF06678.11 PXF39847.1 - 1.3 9.0 5.9 0.63 10.0 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1179) Nucleoporin2 PF04096.14 PXF39851.1 - 3.5e-30 105.1 0.0 5.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase SpoU_methylas_C PF12105.8 PXF39851.1 - 0.1 12.3 0.1 12 5.7 0.0 2.9 3 0 0 3 3 3 0 SpoU, rRNA methylase, C-terminal DUF1759 PF03564.15 PXF39854.1 - 0.0035 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Aminotran_4 PF01063.19 PXF39854.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Amino-transferase class IV PPDK_N PF01326.19 PXF39857.1 - 3.1e-09 36.6 0.0 8.4e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PPDK_N PF01326.19 PXF39858.1 - 1.7e-36 126.2 0.8 1.5e-34 119.7 0.8 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain APH PF01636.23 PXF39860.1 - 2.9e-07 30.7 0.4 1.4e-06 28.4 0.3 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF39860.1 - 0.0095 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Transposase_21 PF02992.14 PXF39861.1 - 4.6e-15 55.4 0.5 3.9e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 PXF39861.1 - 0.098 12.3 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) LnmK_N_HDF PF18238.1 PXF39862.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain EamA PF00892.20 PXF39863.1 - 1e-25 90.5 32.4 6.2e-13 49.1 8.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PXF39863.1 - 0.001 18.5 5.3 0.001 18.5 5.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 PXF39863.1 - 0.0021 17.1 6.7 0.062 12.2 1.3 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Retrotran_gag_2 PF14223.6 PXF39865.1 - 4.5e-18 65.3 0.4 7.2e-18 64.6 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Rtf2 PF04641.12 PXF39865.1 - 0.037 13.4 3.6 0.063 12.6 3.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PCIF1_WW PF12237.8 PXF39870.1 - 0.0022 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF410 PF04190.13 PXF39870.1 - 0.17 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) SET PF00856.28 PXF39871.1 - 5.3e-15 56.2 0.1 2.4e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 SET domain M60-like_N PF17291.2 PXF39871.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases Toxin_38 PF14866.6 PXF39875.1 - 0.052 13.9 1.5 2.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Potassium channel toxin SAP25 PF15476.6 PXF39875.1 - 7.4 6.2 7.1 8.5 6.0 1.2 2.1 1 1 1 2 2 2 0 Histone deacetylase complex subunit SAP25 CNOT1_HEAT PF16418.5 PXF39882.1 - 1.1e-05 25.6 0.5 1.6e-05 25.0 0.5 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 PXF39882.1 - 1.3e-05 24.5 0.0 3.4e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain YqaJ PF09588.10 PXF39884.1 - 1.8e-06 28.2 0.1 6.5e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain DDE_Tnp_1_7 PF13843.6 PXF39884.1 - 0.016 14.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Transposase IS4 PAS_8 PF13188.7 PXF39884.1 - 0.019 15.0 0.1 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 PAS domain Tnp_zf-ribbon_2 PF13842.6 PXF39884.1 - 0.027 15.3 2.8 0.088 13.6 2.8 2.0 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon AAA_16 PF13191.6 PXF39884.1 - 0.038 14.4 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PMM PF03332.13 PXF39885.1 - 9.9e-29 100.7 0.0 1.1e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DUF1682 PF07946.14 PXF39886.1 - 0.19 10.9 8.0 0.22 10.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Arf PF00025.21 PXF39890.1 - 7.4e-78 260.0 0.1 8.6e-78 259.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PXF39890.1 - 1.8e-14 54.0 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PXF39890.1 - 1.3e-13 50.9 0.6 1.9e-09 37.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PXF39890.1 - 1.6e-13 50.6 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PXF39890.1 - 1.6e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PXF39890.1 - 3.2e-12 46.3 0.0 3.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF39890.1 - 8.8e-06 25.8 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PXF39890.1 - 0.0031 16.8 0.5 0.013 14.9 0.5 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 PXF39890.1 - 0.1 12.2 0.2 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AHSP PF09236.10 PXF39891.1 - 0.077 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein AAA PF00004.29 PXF39892.1 - 1.5e-41 141.9 0.1 3e-41 141.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF39892.1 - 3.3e-12 46.0 0.1 8.8e-12 44.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PXF39892.1 - 2.1e-08 34.7 0.3 3.4e-05 24.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 PXF39892.1 - 1.9e-06 27.7 0.0 5.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 PXF39892.1 - 2.1e-06 27.8 0.1 1.8e-05 24.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PXF39892.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PXF39892.1 - 3.2e-05 24.1 0.0 0.00045 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PXF39892.1 - 3.3e-05 24.2 0.8 0.034 14.4 0.0 2.8 2 1 1 3 3 3 2 AAA domain TIP49 PF06068.13 PXF39892.1 - 0.00049 19.4 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PXF39892.1 - 0.00099 19.7 0.0 0.0038 17.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 PXF39892.1 - 0.0037 17.0 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 PXF39892.1 - 0.0039 16.4 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PXF39892.1 - 0.0043 17.4 0.0 0.0092 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase DUF4200 PF13863.6 PXF39892.1 - 0.0047 17.3 1.5 0.0094 16.3 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_7 PF12775.7 PXF39892.1 - 0.005 16.4 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PXF39892.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PXF39892.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 PXF39892.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PXF39892.1 - 0.017 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain HBM PF16591.5 PXF39892.1 - 0.026 14.0 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain ATPase PF06745.13 PXF39892.1 - 0.03 13.7 0.6 0.13 11.6 0.0 2.2 3 0 0 3 3 3 0 KaiC TPR_MLP1_2 PF07926.12 PXF39892.1 - 0.03 14.4 2.6 0.053 13.6 2.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_3 PF07726.11 PXF39892.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 PXF39892.1 - 0.036 13.8 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PXF39892.1 - 0.039 13.9 0.0 0.19 11.6 0.0 2.2 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 PXF39892.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PXF39892.1 - 0.044 14.0 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PXF39892.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.14 PXF39892.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CENP-Q PF13094.6 PXF39892.1 - 0.063 13.5 2.7 0.46 10.7 1.9 2.5 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Parvo_NS1 PF01057.17 PXF39892.1 - 0.063 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.14 PXF39892.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.6 PXF39892.1 - 0.093 12.9 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PXF39892.1 - 0.1 13.1 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter CPT PF07931.12 PXF39892.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 PXF39892.1 - 0.2 11.2 0.6 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 PXF39892.1 - 0.25 10.0 0.9 6.6 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain G_glu_transpept PF01019.21 PXF39893.1 - 2e-128 429.4 0.0 8.9e-90 301.9 0.0 2.5 2 1 0 2 2 2 2 Gamma-glutamyltranspeptidase Resolvase PF00239.21 PXF39893.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain Ras PF00071.22 PXF39894.1 - 2.3e-31 108.6 0.1 2.7e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF39894.1 - 8.6e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF39894.1 - 1.5e-05 24.5 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PXF39894.1 - 0.0037 16.6 0.2 0.0044 16.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PXF39894.1 - 0.0061 15.8 0.2 0.015 14.5 0.2 1.6 1 1 0 1 1 1 1 G-protein alpha subunit DLIC PF05783.11 PXF39894.1 - 0.01 14.7 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 PXF39894.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 PXF39894.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Uma2 PF05685.12 PXF39924.1 - 1e-07 31.6 0.4 7.3e-07 28.9 0.4 2.2 1 1 0 1 1 1 1 Putative restriction endonuclease Borrelia_P83 PF05262.11 PXF39924.1 - 0.018 13.6 42.6 0.023 13.2 42.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 PXF39924.1 - 6.8 4.9 45.6 10 4.3 45.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 PXF39926.1 - 1.4e-32 113.1 0.0 1.6e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF39926.1 - 4.7e-18 65.4 0.0 5.2e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF39926.1 - 8.4e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF39926.1 - 0.0053 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_18 PF13238.6 PXF39926.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Kinase-like PF14531.6 PXF39926.1 - 0.13 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF676 PF05057.14 PXF39927.1 - 5.8e-21 75.0 0.1 7.1e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PXF39927.1 - 0.00051 20.0 0.0 0.00065 19.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cupin_1 PF00190.22 PXF39929.1 - 1.5e-07 31.2 0.1 2.2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF39929.1 - 2.5e-05 23.9 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 PXF39929.1 - 0.012 15.5 0.1 0.033 14.1 0.1 1.7 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase DUF4376 PF14301.6 PXF39930.1 - 0.025 14.9 1.1 0.039 14.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Spc7 PF08317.11 PXF39931.1 - 0.00069 18.6 17.7 0.0073 15.2 16.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein FPP PF05911.11 PXF39931.1 - 0.0017 16.6 10.0 0.0028 15.9 10.0 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 PXF39931.1 - 0.0026 17.5 9.5 0.0038 17.0 9.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Filament PF00038.21 PXF39931.1 - 0.0027 17.3 15.4 0.065 12.8 3.5 2.0 1 1 1 2 2 2 2 Intermediate filament protein MscS_porin PF12795.7 PXF39931.1 - 0.012 15.1 15.8 0.026 14.1 15.8 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 PXF39931.1 - 0.016 15.3 9.0 0.021 14.9 9.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 PXF39931.1 - 0.032 13.1 12.4 0.039 12.8 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spectrin PF00435.21 PXF39931.1 - 0.052 14.0 12.2 0.51 10.9 3.2 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF2730 PF10805.8 PXF39931.1 - 0.054 13.6 0.9 0.11 12.6 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) KxDL PF10241.9 PXF39931.1 - 0.066 13.5 6.5 0.9 9.9 1.2 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein HemX PF04375.14 PXF39931.1 - 0.073 12.3 11.2 0.54 9.5 1.5 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc29 PF17082.5 PXF39931.1 - 0.12 12.2 8.0 0.039 13.8 2.0 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 PXF39931.1 - 0.12 12.4 6.1 0.87 9.6 1.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PEARLI-4 PF05278.12 PXF39931.1 - 0.16 11.6 11.2 1.2 8.7 5.7 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) HrpB7 PF09486.10 PXF39931.1 - 0.16 12.4 20.3 0.29 11.5 20.3 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Phage_int_SAM_6 PF18644.1 PXF39931.1 - 0.16 12.0 0.9 0.27 11.3 0.3 1.6 2 0 0 2 2 1 0 Phage integrase SAM-like domain BRE1 PF08647.11 PXF39931.1 - 0.26 11.4 11.8 0.2 11.8 3.6 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase YscO PF07321.12 PXF39931.1 - 0.28 11.1 24.5 0.75 9.7 15.5 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO AAA_13 PF13166.6 PXF39931.1 - 0.34 9.5 12.2 0.67 8.5 12.2 1.4 1 1 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 PXF39931.1 - 0.43 10.4 8.9 0.084 12.7 3.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 BST2 PF16716.5 PXF39931.1 - 0.43 11.2 11.6 0.95 10.1 5.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 PXF39931.1 - 0.44 10.1 14.1 1 8.8 14.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.11 PXF39931.1 - 0.47 10.7 19.1 7.3 6.8 19.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 PXF39931.1 - 0.63 8.5 7.8 0.81 8.2 7.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 PXF39931.1 - 0.66 10.2 7.5 1.6 8.9 1.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 PXF39931.1 - 0.7 9.9 17.5 1.8 8.6 17.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 PXF39931.1 - 0.79 9.0 15.3 0.76 9.0 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 PXF39931.1 - 0.82 9.7 18.8 1.8 8.6 16.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.18 PXF39931.1 - 0.88 10.3 8.0 0.57 10.9 0.7 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TSNAXIP1_N PF15739.5 PXF39931.1 - 1.1 9.6 9.3 0.64 10.4 2.7 2.3 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus APG6_N PF17675.1 PXF39931.1 - 1.2 9.7 17.6 5.2 7.6 17.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 PXF39931.1 - 1.2 9.8 6.8 0.65 10.7 0.3 2.7 1 1 3 4 4 3 0 SlyX BLOC1_2 PF10046.9 PXF39931.1 - 1.3 9.4 7.8 3.9 7.8 1.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 PXF39931.1 - 1.7 8.0 19.4 1.1 8.6 10.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-ZPR1 PF03367.13 PXF39931.1 - 1.8 8.4 4.8 1.7 8.5 3.4 1.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain TPR_MLP1_2 PF07926.12 PXF39931.1 - 1.9 8.6 24.2 2.2 8.4 4.1 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.11 PXF39931.1 - 2 8.4 14.4 2.4 8.2 8.3 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p GPS2_interact PF15784.5 PXF39931.1 - 3.2 8.3 11.2 2.3 8.7 3.1 2.4 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF4407 PF14362.6 PXF39931.1 - 3.9 6.7 15.6 6.6 6.0 14.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PXF39931.1 - 4.2 6.4 21.3 19 4.2 21.3 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 PXF39931.1 - 5.3 5.8 4.9 5.9 5.7 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Csm1_N PF18504.1 PXF39931.1 - 5.5 7.4 13.7 3.7 8.0 2.4 3.0 1 1 1 3 3 3 0 Csm1 N-terminal domain DUF4200 PF13863.6 PXF39931.1 - 5.7 7.4 20.5 5.1 7.5 8.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 PXF39931.1 - 6.1 6.9 21.5 1.2 9.2 6.4 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.19 PXF39931.1 - 6.6 6.4 15.6 6.9 6.3 5.0 2.6 1 1 2 3 3 3 0 GrpE Jnk-SapK_ap_N PF09744.9 PXF39931.1 - 7.8 6.7 19.6 2.7 8.2 11.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-K PF11802.8 PXF39931.1 - 8 5.9 13.9 20 4.6 12.6 1.7 1 1 0 1 1 1 0 Centromere-associated protein K FPP PF05911.11 PXF39932.1 - 0.00086 17.6 1.8 0.00099 17.4 1.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FliJ PF02050.16 PXF39932.1 - 0.0047 17.1 8.3 0.015 15.5 8.6 1.6 1 1 1 2 2 2 1 Flagellar FliJ protein OmpH PF03938.14 PXF39932.1 - 0.032 14.6 0.7 0.04 14.3 0.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3450 PF11932.8 PXF39932.1 - 0.087 12.1 5.8 0.1 11.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 PXF39932.1 - 0.11 12.0 3.4 0.14 11.7 3.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3708 PF12501.8 PXF39932.1 - 0.12 12.2 0.6 0.14 11.9 0.6 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Spc7 PF08317.11 PXF39932.1 - 0.32 9.8 6.2 0.39 9.5 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PXF39932.1 - 0.58 10.2 14.6 15 5.7 14.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YscO PF07321.12 PXF39932.1 - 0.8 9.6 14.4 1.4 8.9 14.4 1.4 1 1 0 1 1 1 0 Type III secretion protein YscO HAUS6_N PF14661.6 PXF39932.1 - 0.92 9.0 5.8 1.2 8.7 5.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FUSC PF04632.12 PXF39932.1 - 2.8 6.4 6.2 3.4 6.1 6.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 PXF39932.1 - 9 5.3 11.4 11 4.9 11.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1775 PF07987.11 PXF39935.1 - 1.4e-22 80.6 0.0 2.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) DUF1775 PF07987.11 PXF39936.1 - 4.9e-19 69.1 0.0 7.6e-19 68.4 0.0 1.3 1 1 0 1 1 1 1 Domain of unkown function (DUF1775) AXE1 PF05448.12 PXF39938.1 - 0.039 12.6 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) zf-C2H2 PF00096.26 PXF39939.1 - 8.3e-15 54.3 15.3 9.3e-05 22.7 0.7 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF39939.1 - 3.2e-11 43.1 14.6 0.0021 18.8 1.7 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF39939.1 - 7e-11 42.0 11.5 4.1e-06 27.0 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 PXF39939.1 - 2e-05 24.2 9.1 0.038 13.8 0.1 3.6 3 1 0 3 3 3 2 C2H2-type zinc-finger domain C1_2 PF03107.16 PXF39939.1 - 0.00042 20.6 2.5 1.4 9.3 0.1 3.2 3 0 0 3 3 3 1 C1 domain CpXC PF14353.6 PXF39939.1 - 0.0005 20.1 3.8 0.25 11.4 0.0 2.9 1 1 2 3 3 3 2 CpXC protein zinc_ribbon_4 PF13717.6 PXF39939.1 - 0.00066 19.5 2.5 0.27 11.2 0.4 3.1 2 1 0 2 2 2 1 zinc-ribbon domain zf-met PF12874.7 PXF39939.1 - 0.00073 19.8 6.5 0.11 13.0 0.7 2.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 PXF39939.1 - 0.00074 20.2 7.9 0.53 11.0 0.6 3.0 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_7 PF15269.6 PXF39939.1 - 0.00094 19.2 8.5 2.2 8.4 0.0 3.1 2 1 1 3 3 3 2 Zinc-finger zf-Di19 PF05605.12 PXF39939.1 - 0.0023 18.2 2.6 0.0023 18.2 2.6 2.1 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 PXF39939.1 - 0.0029 17.2 3.6 0.35 10.5 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 PXF39939.1 - 0.012 15.6 3.4 0.098 12.7 3.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Actin_micro PF17003.5 PXF39939.1 - 0.015 14.5 10.2 0.64 9.1 1.5 2.9 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_8 PF15909.5 PXF39939.1 - 0.019 15.3 7.4 0.41 11.0 1.5 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon HypA PF01155.19 PXF39939.1 - 0.019 15.0 3.2 0.43 10.6 0.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_2 PF12756.7 PXF39939.1 - 0.021 15.2 9.3 0.77 10.1 3.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rubredoxin_2 PF18073.1 PXF39939.1 - 0.039 13.7 10.6 0.14 11.9 0.9 3.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain zinc_ribbon_15 PF17032.5 PXF39939.1 - 0.051 14.3 1.8 0.67 10.8 1.9 2.0 1 1 1 2 2 2 0 zinc-ribbon family Vps36-NZF-N PF16988.5 PXF39939.1 - 0.055 12.9 2.0 5.3 6.5 0.0 2.8 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OrfB_Zn_ribbon PF07282.11 PXF39939.1 - 0.063 13.2 8.6 2.1 8.3 0.2 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-C2H2_6 PF13912.6 PXF39939.1 - 0.074 13.1 9.4 2 8.5 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 PXF39939.1 - 0.18 11.7 6.2 5.1 7.1 2.2 2.9 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 PXF39939.1 - 0.22 11.7 10.9 4.4 7.5 3.4 3.0 1 1 2 3 3 3 0 Zinc ribbon domain Rubredoxin PF00301.20 PXF39939.1 - 0.4 10.7 4.0 22 5.1 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin zf-CSL PF05207.13 PXF39939.1 - 0.44 10.3 6.9 1.3 8.8 0.6 2.4 1 1 1 2 2 2 0 CSL zinc finger zf-BED PF02892.15 PXF39939.1 - 0.52 10.4 12.6 1.4 9.0 0.3 3.0 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.12 PXF39939.1 - 0.68 10.2 7.7 4.6 7.5 1.3 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RanBP PF00641.18 PXF39939.1 - 1.1 8.6 7.4 0.62 9.4 0.4 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-C2H2_11 PF16622.5 PXF39939.1 - 1.9 8.3 14.8 2.7 7.8 0.1 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-AN1 PF01428.16 PXF39939.1 - 2.9 8.1 8.7 10 6.4 0.1 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger zf-C2H2_jaz PF12171.8 PXF39939.1 - 4.8 7.6 8.5 5.1 7.5 1.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Sec23_Sec24 PF04810.15 PXF39939.1 - 4.8 7.3 9.6 10 6.2 4.7 2.9 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf_C2H2_ZHX PF18387.1 PXF39939.1 - 4.9 6.9 9.3 6.3 6.5 0.2 2.9 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain FAT PF02259.23 PXF39940.1 - 2.3e-35 122.4 6.5 2.3e-35 122.4 6.5 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 PXF39940.1 - 0.00029 20.8 0.0 0.00088 19.2 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RIX1 PF08167.12 PXF39940.1 - 0.016 14.9 0.1 0.016 14.9 0.1 4.0 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis TPR_8 PF13181.6 PXF39940.1 - 1 9.7 2.7 7.7 7.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat COG2 PF06148.11 PXF39940.1 - 1.7 8.8 5.5 8.5 6.5 5.5 2.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_1 PF00515.28 PXF39940.1 - 5.2 7.1 5.5 4.4 7.3 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SWIRM-assoc_2 PF16496.5 PXF39942.1 - 5.5e-42 144.1 0.7 5.5e-42 144.1 0.7 2.4 3 1 0 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 PXF39942.1 - 1.7e-29 102.0 0.0 5.6e-29 100.3 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 PXF39942.1 - 1.3e-09 38.0 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 PXF39942.1 - 2.3e-07 30.5 6.7 5.1e-07 29.4 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 PXF39942.1 - 0.00047 20.4 4.2 0.0005 20.3 1.1 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 PXF39942.1 - 0.03 14.3 1.7 0.082 12.9 1.7 1.7 1 0 0 1 1 1 0 SWIRM-associated region 1 HA2 PF04408.23 PXF39943.1 - 2e-25 89.2 0.0 7.9e-25 87.2 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PXF39943.1 - 5.6e-23 81.1 0.0 1.1e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 PXF39943.1 - 3.9e-12 46.3 0.3 8.3e-12 45.3 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 PXF39943.1 - 2.6e-11 43.9 0.0 6.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF39943.1 - 1.1e-06 28.5 0.1 2.1e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PXF39943.1 - 4.9e-05 23.6 1.1 0.00041 20.6 0.5 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF39943.1 - 0.0039 16.9 0.1 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF39943.1 - 0.01 14.9 0.0 0.043 12.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 PXF39943.1 - 0.013 16.0 0.5 0.19 12.3 0.1 2.6 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.6 PXF39943.1 - 0.077 13.0 0.6 1.3 9.1 0.6 2.6 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 PXF39943.1 - 0.097 12.6 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 PXF39943.1 - 0.12 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 PXF39943.1 - 0.12 11.8 0.1 0.36 10.3 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein ChAPs PF09295.10 PXF39944.1 - 1.1e-36 126.7 0.4 9e-36 123.7 0.4 2.0 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 PXF39944.1 - 2e-07 30.7 1.0 0.27 11.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF39944.1 - 3e-07 30.0 0.4 0.026 14.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF39944.1 - 1.4e-05 25.5 4.0 0.02 15.4 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF39944.1 - 1.7e-05 25.2 8.6 0.056 14.3 0.4 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF39944.1 - 2.8e-05 23.9 3.8 0.26 11.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 PXF39944.1 - 0.0009 18.3 1.6 0.0061 15.5 1.3 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 PXF39944.1 - 0.018 15.2 1.0 0.079 13.2 0.8 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PV-1 PF06637.11 PXF39944.1 - 0.018 13.9 0.1 0.041 12.7 0.1 1.5 1 0 0 1 1 1 0 PV-1 protein (PLVAP) TPR_9 PF13371.6 PXF39944.1 - 0.041 14.0 2.7 6 7.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF39944.1 - 0.091 13.1 0.7 3.6 8.0 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 PXF39944.1 - 0.14 10.9 0.2 0.21 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_16 PF13432.6 PXF39944.1 - 0.79 10.4 10.3 0.87 10.3 2.6 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat UPF0547 PF10571.9 PXF39945.1 - 2.2e-06 27.6 20.4 8.3e-05 22.6 4.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zf-tcix PF14952.6 PXF39945.1 - 0.00012 21.6 18.1 0.00034 20.1 7.9 2.4 1 1 1 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding DZR PF12773.7 PXF39945.1 - 0.067 13.2 16.8 0.15 12.1 16.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 PXF39945.1 - 0.15 11.7 9.0 0.062 12.9 1.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zn-ribbon_8 PF09723.10 PXF39945.1 - 2.2 8.5 16.7 0.62 10.2 4.0 3.4 2 1 0 3 3 3 0 Zinc ribbon domain TerY_C PF15616.6 PXF39945.1 - 5.7 7.1 11.7 2 8.6 2.0 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain zinc_ribbon_15 PF17032.5 PXF39945.1 - 8.3 7.2 16.8 9.2 7.1 1.7 2.0 1 1 1 2 2 2 0 zinc-ribbon family Putative_PNPOx PF01243.20 PXF39946.1 - 3.1e-25 88.2 0.0 4.9e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 PXF39946.1 - 7.2e-18 64.4 0.8 1.5e-17 63.4 0.8 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 PXF39946.1 - 2.8e-05 24.6 0.1 5.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NB-ARC PF00931.22 PXF39947.1 - 4.5e-14 52.3 0.0 8.7e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF39947.1 - 1.5e-11 44.5 11.4 0.00032 20.9 0.0 7.6 4 2 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain APAF1_C PF17908.1 PXF39947.1 - 2.5e-05 24.3 0.0 5.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 APAF-1 helical domain WD40 PF00400.32 PXF39947.1 - 0.00013 22.7 15.4 0.047 14.6 0.1 7.6 8 0 0 8 8 8 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PXF39947.1 - 0.00024 20.2 0.3 0.05 12.6 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 PXF39947.1 - 0.025 13.0 0.1 0.053 11.9 0.1 1.5 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hira PF07569.11 PXF39947.1 - 0.068 12.9 4.3 0.61 9.8 0.1 3.6 2 1 0 3 3 3 0 TUP1-like enhancer of split HPS3_N PF14761.6 PXF39947.1 - 0.1 12.1 0.0 8.7 5.8 0.1 3.4 3 1 0 3 3 3 0 Hermansky-Pudlak syndrome 3 NAP PF00956.18 PXF39948.1 - 0.03 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) UAA PF08449.11 PXF39952.1 - 6.7e-05 22.2 11.9 0.00011 21.6 11.9 1.2 1 0 0 1 1 1 1 UAA transporter family ArAE_1 PF06081.11 PXF39952.1 - 0.0087 16.2 2.0 0.0087 16.2 2.0 1.7 1 1 0 1 1 1 1 Aromatic acid exporter family member 1 DUF3687 PF12459.8 PXF39952.1 - 0.062 12.8 0.3 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein EamA PF00892.20 PXF39952.1 - 0.13 12.5 21.0 0.026 14.7 11.5 2.2 2 0 0 2 2 2 0 EamA-like transporter family Toprim_C_rpt PF13368.6 PXF39954.1 - 2.3e-26 91.5 0.2 2.1e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 Topoisomerase C-terminal repeat Pol_alpha_B_N PF08418.10 PXF39954.1 - 0.0068 16.4 3.1 0.0094 15.9 0.7 1.9 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal IHABP4_N PF16174.5 PXF39954.1 - 0.31 11.6 9.7 0.1 13.2 6.6 1.7 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4637 PF15470.6 PXF39954.1 - 9.8 5.9 7.8 1.4 8.6 3.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Topoisom_bac PF01131.20 PXF39955.1 - 4.8e-99 332.2 0.0 6.3e-99 331.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PXF39955.1 - 3.7e-22 78.5 0.0 8e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 PXF39955.1 - 0.0082 16.6 0.0 0.035 14.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 PXF39955.1 - 0.039 14.4 0.0 0.18 12.2 0.0 2.2 1 1 0 1 1 1 0 Toprim-like CitT PF12431.8 PXF39956.1 - 0.082 13.3 0.1 0.31 11.5 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator HTH_23 PF13384.6 PXF39956.1 - 0.099 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain SF3b1 PF08920.10 PXF39957.1 - 0.027 15.0 0.0 0.031 14.8 0.0 1.2 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 HTH_ABP1_N PF18107.1 PXF39958.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Big_7 PF17957.1 PXF39959.1 - 5.6e-05 23.8 0.0 0.0015 19.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial Ig domain DUF5016 PF16408.5 PXF39961.1 - 0.073 13.1 0.1 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5016) Peptidase_C14 PF00656.22 PXF39964.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Caspase domain RNase_E_G PF10150.9 PXF39965.1 - 0.023 14.2 1.1 0.025 14.0 1.1 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family SNF2_N PF00176.23 PXF39966.1 - 9.8e-36 123.2 0.0 1.3e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF39967.1 - 4.9e-07 30.1 0.0 1e-06 29.1 0.0 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Glycos_transf_2 PF00535.26 PXF39968.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PXF39968.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF4558 PF15104.6 PXF39972.1 - 0.023 14.7 12.7 0.028 14.5 12.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) DNA_photolyase PF00875.18 PXF39972.1 - 0.037 14.0 0.9 0.041 13.9 0.9 1.1 1 0 0 1 1 1 0 DNA photolyase DUF2470 PF10615.9 PXF39972.1 - 0.05 14.2 1.3 0.051 14.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) Rep_fac-A_C PF08646.10 PXF39972.1 - 0.079 12.7 4.1 0.089 12.5 4.1 1.0 1 0 0 1 1 1 0 Replication factor-A C terminal domain Tox-ODYAM1 PF15642.6 PXF39972.1 - 0.39 9.6 6.1 0.46 9.4 6.1 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus SRA1 PF07304.11 PXF39974.1 - 0.0032 17.3 0.1 0.0039 17.0 0.1 1.2 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) F_bP_aldolase PF01116.20 PXF39974.1 - 0.0048 16.4 0.1 0.0055 16.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TPK_catalytic PF04263.16 PXF39974.1 - 0.025 14.6 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain MRF_C1 PF13887.6 PXF39974.1 - 0.16 11.2 0.1 0.39 9.9 0.1 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Uma2 PF05685.12 PXF39975.1 - 2.7e-11 43.3 0.3 2.5e-09 36.9 0.3 2.3 1 1 0 1 1 1 1 Putative restriction endonuclease DUF4407 PF14362.6 PXF39975.1 - 0.52 9.6 11.1 0.66 9.3 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 PXF39975.1 - 0.97 7.5 8.7 1.4 7.0 8.7 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4597 PF15366.6 PXF39975.1 - 1.1 9.0 5.2 0.73 9.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) TatD_DNase PF01026.21 PXF39977.1 - 7.4e-54 182.8 0.0 8.6e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 PXF39977.1 - 0.17 11.6 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Amidohydrolase Aminotran_1_2 PF00155.21 PXF39978.1 - 2e-37 129.2 0.0 3.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3180 PF11377.8 PXF39978.1 - 0.057 13.6 0.5 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) AAA PF00004.29 PXF39980.1 - 2.5e-56 189.7 0.0 5.4e-37 127.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF39980.1 - 2e-19 69.1 0.4 1.3e-12 47.3 0.0 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 PXF39980.1 - 2.1e-13 51.0 1.5 4.5e-06 27.1 0.3 4.0 2 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 PXF39980.1 - 7.6e-09 35.5 0.0 0.0013 18.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PXF39980.1 - 2.3e-08 34.1 0.4 0.0072 16.3 0.0 4.5 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF39980.1 - 3.6e-06 27.3 0.2 0.18 12.0 0.0 4.4 2 2 1 4 4 4 1 AAA domain Rad17 PF03215.15 PXF39980.1 - 5.3e-06 26.5 0.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain TIP49 PF06068.13 PXF39980.1 - 1.5e-05 24.4 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 PXF39980.1 - 6e-05 23.2 0.0 0.019 15.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 PXF39980.1 - 7.3e-05 22.1 0.0 0.035 13.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 PXF39980.1 - 0.00034 19.9 0.0 0.91 8.6 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 PXF39980.1 - 0.00038 20.6 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PXF39980.1 - 0.00054 19.8 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PXF39980.1 - 0.0025 18.2 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 PXF39980.1 - 0.0026 17.5 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PXF39980.1 - 0.0072 15.9 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 PXF39980.1 - 0.0084 16.1 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PXF39980.1 - 0.0087 15.9 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PXF39980.1 - 0.0095 15.9 0.0 1.1 9.1 0.0 3.1 2 1 1 3 3 3 1 NTPase AAA_18 PF13238.6 PXF39980.1 - 0.013 16.0 0.0 0.62 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PXF39980.1 - 0.024 14.7 0.0 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PXF39980.1 - 0.029 14.3 0.1 8.4 6.3 0.0 3.5 4 1 0 4 4 4 0 NACHT domain AAA_30 PF13604.6 PXF39980.1 - 0.035 13.8 0.6 7.6 6.2 0.0 3.4 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 PXF39980.1 - 0.14 11.5 1.8 14 5.0 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 PXF39980.1 - 0.18 11.6 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-C2H2 PF00096.26 PXF39981.1 - 7.9e-07 29.2 8.0 6.6e-05 23.2 0.7 3.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF39981.1 - 1e-05 26.0 5.7 0.00048 20.7 0.3 4.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF39981.1 - 0.00014 21.5 0.5 0.00014 21.5 0.5 2.9 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PXF39981.1 - 0.0032 17.4 1.2 0.0032 17.4 1.2 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF39981.1 - 0.0041 17.4 1.7 0.72 10.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PXF39981.1 - 0.011 16.1 0.3 0.011 16.1 0.3 5.3 6 0 0 6 6 6 0 Zinc-finger double domain zf-met PF12874.7 PXF39981.1 - 0.021 15.2 2.9 0.023 15.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 PXF39981.1 - 0.11 13.2 4.9 4.5 8.0 4.9 2.4 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 PXF39981.1 - 0.13 12.1 4.2 3.5 7.5 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 PXF39981.1 - 1.2 9.5 7.9 7.7 6.9 0.6 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RING_2 PF13639.6 PXF39983.1 - 1.3e-13 51.0 8.1 2.6e-13 50.1 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF39983.1 - 1.3e-09 37.6 4.5 1.3e-09 37.6 4.5 1.9 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF39983.1 - 5.3e-07 29.4 7.0 9.6e-07 28.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF39983.1 - 1.2e-06 28.3 6.5 2.2e-06 27.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF39983.1 - 5.7e-05 22.9 7.9 0.0001 22.1 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF39983.1 - 6.3e-05 23.2 9.5 0.00024 21.3 9.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF39983.1 - 0.00042 20.2 6.3 0.00076 19.4 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF39983.1 - 0.00069 19.6 7.3 0.0014 18.6 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PXF39983.1 - 0.11 12.2 9.8 0.19 11.4 9.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PXF39983.1 - 0.29 11.3 8.1 1.3 9.3 8.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 PXF39983.1 - 0.71 9.8 11.8 1.4 8.8 11.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Y_phosphatase2 PF03162.13 PXF39984.1 - 8.7e-59 197.8 0.0 9.6e-59 197.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PXF39984.1 - 2.2e-07 31.1 0.0 3.2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PXF39984.1 - 0.0048 16.7 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PXF39984.1 - 0.0094 15.5 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CTP_transf_like PF01467.26 PXF39985.1 - 1.9e-05 24.9 0.1 9.9e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 PXF39985.1 - 0.16 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 ATP-sulfurylase Exo_endo_phos PF03372.23 PXF39986.1 - 0.074 12.6 0.1 0.55 9.7 0.1 2.2 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Glutaredoxin2_C PF04399.13 PXF39990.1 - 3.1e-34 117.6 0.0 4e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 PXF39990.1 - 1.8e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF39990.1 - 1.9e-05 24.9 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PXF39990.1 - 0.00034 20.8 0.0 0.00072 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Choline_sulf_C PF12411.8 PXF39990.1 - 0.025 14.4 1.5 2.9 7.8 0.1 2.3 1 1 1 2 2 2 0 Choline sulfatase enzyme C terminal VWA PF00092.28 PXF39991.1 - 1.4e-15 57.9 0.1 1.8e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF39991.1 - 1.3e-09 38.6 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF39991.1 - 6.7e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF39991.1 - 0.0064 15.7 0.1 1.9 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) SOGA PF11365.8 PXF39995.1 - 0.35 12.0 3.7 1.9 9.7 1.4 2.3 2 1 0 2 2 2 0 Protein SOGA DUF463 PF04317.12 PXF39996.1 - 0.039 12.9 0.1 0.046 12.6 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Hydrolase PF00702.26 PXF39998.1 - 4.8e-12 46.6 0.2 7.5e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF39998.1 - 1.6e-05 24.8 0.0 0.00017 21.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF39998.1 - 0.0083 16.5 0.0 1.6 9.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PXF39998.1 - 0.037 14.1 0.0 0.74 10.0 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HSP33 PF01430.19 PXF39998.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 Hsp33 protein AbiEi_4 PF13338.6 PXF39998.1 - 0.2 11.8 1.0 0.69 10.1 0.5 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin IGPS PF00218.21 PXF39999.1 - 3.6e-09 36.2 0.2 4.3e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NB-ARC PF00931.22 PXF40001.1 - 3.8e-09 36.1 0.0 4.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain RepC PF06504.11 PXF40002.1 - 0.00061 19.1 0.3 0.00072 18.8 0.3 1.1 1 0 0 1 1 1 1 Replication protein C (RepC) bZIP_1 PF00170.21 PXF40002.1 - 0.0011 19.0 13.4 0.0032 17.5 11.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF444 PF04285.12 PXF40002.1 - 0.011 14.8 3.7 0.013 14.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF1617 PF07761.12 PXF40002.1 - 0.058 13.5 1.7 0.096 12.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1617) rve PF00665.26 PXF40003.1 - 6.8e-06 26.3 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Coprogen_oxidas PF01218.18 PXF40004.1 - 1.3e-10 40.6 0.0 2.7e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Kelch_4 PF13418.6 PXF40005.1 - 3.6e-14 52.5 7.8 0.00051 20.0 0.0 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PXF40005.1 - 1.4e-12 47.3 0.1 0.041 13.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PXF40005.1 - 3.2e-11 43.2 0.1 0.0076 16.5 0.0 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF40005.1 - 7.1e-10 38.8 0.2 0.00078 19.6 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 PXF40005.1 - 6.2e-06 25.7 2.8 0.0064 16.0 0.2 3.7 3 1 0 3 3 3 2 Kelch motif FPP PF05911.11 PXF40005.1 - 0.0016 16.7 27.4 0.0016 16.7 27.4 3.3 1 1 1 3 3 3 1 Filament-like plant protein, long coiled-coil Laminin_B PF00052.18 PXF40005.1 - 0.043 13.7 1.0 0.12 12.3 1.0 1.7 1 0 0 1 1 1 0 Laminin B (Domain IV) CALCOCO1 PF07888.11 PXF40005.1 - 0.56 9.0 65.4 0.2 10.5 22.4 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 PXF40005.1 - 0.74 10.0 66.8 4.7 7.4 9.4 4.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 PXF40005.1 - 0.75 9.9 58.2 0.014 15.4 13.6 4.7 2 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 PXF40005.1 - 4.6 7.9 51.9 0.15 12.7 6.1 6.1 2 2 3 5 5 5 0 Initiation control protein YabA Cyclin_N PF00134.23 PXF40006.1 - 6.1e-06 26.0 0.2 1.8e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Med26_C PF15693.5 PXF40006.1 - 0.16 12.1 1.9 0.29 11.3 1.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal HA2 PF04408.23 PXF40008.1 - 1.2e-21 77.0 0.0 2.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PXF40008.1 - 4.9e-19 68.5 0.0 1.1e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 PXF40008.1 - 4e-09 36.5 0.2 7e-09 35.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF40008.1 - 3.5e-06 27.3 0.1 1.8e-05 25.1 0.0 2.3 2 1 0 2 2 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PXF40008.1 - 2.8e-05 24.4 0.1 7.8e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF40008.1 - 0.00024 21.5 0.3 0.00049 20.4 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PXF40008.1 - 0.00026 20.8 0.1 0.00046 20.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 PXF40008.1 - 0.00031 20.4 1.1 0.0014 18.3 1.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 PXF40008.1 - 0.00076 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 PXF40008.1 - 0.0017 18.3 0.1 0.0032 17.4 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 PXF40008.1 - 0.0058 16.6 0.0 3.5 7.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 PXF40008.1 - 0.0098 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 PXF40008.1 - 0.022 14.8 0.0 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phosphoprotein PF00922.17 PXF40008.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein ATPase PF06745.13 PXF40008.1 - 0.042 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 PXF40008.1 - 0.051 13.6 0.3 0.88 9.6 0.3 2.7 2 1 0 2 2 2 0 AAA domain SidE PF12252.8 PXF40008.1 - 0.064 10.8 0.0 0.087 10.4 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein PhoH PF02562.16 PXF40008.1 - 0.071 12.6 0.2 1 8.8 0.0 2.7 4 0 0 4 4 4 0 PhoH-like protein NACHT PF05729.12 PXF40008.1 - 0.11 12.4 0.1 0.52 10.2 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DUF3158 PF11358.8 PXF40008.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Maf PF02545.14 PXF40009.1 - 2.1e-33 115.5 0.0 2.3e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Rimk_N PF18030.1 PXF40009.1 - 0.051 14.0 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 RimK PreATP-grasp domain FPL PF09758.9 PXF40010.1 - 0.079 13.0 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein DNA_ligase_aden PF01653.18 PXF40014.1 - 1.3e-09 37.6 0.0 1.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF40014.1 - 3.4e-09 36.4 0.1 5.3e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain OrsD PF12013.8 PXF40019.1 - 3.7e-09 37.0 2.2 5.9e-09 36.4 0.9 2.1 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 PXF40019.1 - 0.00017 21.9 0.5 0.12 12.8 0.8 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PXF40019.1 - 0.0048 17.3 3.0 1 9.9 0.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF40019.1 - 0.0098 16.7 3.4 3 8.9 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 PXF40019.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 PXF40019.1 - 0.049 13.3 0.8 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-NADH-PPase PF09297.11 PXF40019.1 - 0.33 10.7 2.0 38 4.1 0.0 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Abhydrolase_1 PF00561.20 PXF40021.1 - 3.7e-21 75.9 0.0 2e-20 73.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF40021.1 - 4.5e-10 40.5 0.0 6.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF40021.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1057 PF06342.12 PXF40021.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Glyco_hydro_45 PF02015.16 PXF40024.1 - 1.6e-05 24.9 6.3 1.6e-05 24.9 6.3 3.7 2 2 1 4 4 4 1 Glycosyl hydrolase family 45 SRP-alpha_N PF04086.13 PXF40026.1 - 0.0012 18.9 8.9 0.0016 18.5 8.9 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal NHase_beta PF02211.15 PXF40027.1 - 0.025 14.6 0.4 0.041 13.9 0.4 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit CENP-R PF06729.12 PXF40029.1 - 0.36 10.7 6.8 9.5 6.1 5.0 2.8 2 1 0 2 2 2 0 Kinetochore component, CENP-R Ribonuc_L-PSP PF01042.21 PXF40030.1 - 0.063 13.3 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Endoribonuclease L-PSP Trypsin PF00089.26 PXF40031.1 - 1.6e-33 116.4 0.0 2e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF40031.1 - 1.8e-06 28.9 0.1 3.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.25 PXF40035.1 - 5.8e-12 45.5 0.0 7.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF40035.1 - 9e-07 29.1 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF40035.1 - 4.7e-06 26.1 0.0 6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF40035.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF40035.1 - 0.00036 20.2 0.1 0.00078 19.1 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF40035.1 - 0.0021 16.9 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF40035.1 - 0.087 12.1 0.0 0.16 11.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like KfrA_N PF11740.8 PXF40036.1 - 0.018 15.7 1.3 0.025 15.3 1.3 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HDAC4_Gln PF12203.8 PXF40036.1 - 0.019 15.1 1.8 0.019 15.1 1.8 2.0 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 SEA PF01390.20 PXF40036.1 - 0.12 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 SEA domain DUF4836 PF16120.5 PXF40037.1 - 0.0032 16.5 0.1 0.0032 16.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4836) YqaJ PF09588.10 PXF40039.1 - 0.0001 22.5 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain Phospholip_B PF04916.13 PXF40039.1 - 0.0039 15.8 0.1 0.17 10.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase B M16C_assoc PF08367.11 PXF40041.1 - 3.8e-66 222.8 0.0 5.5e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PXF40041.1 - 1.5e-20 74.0 0.0 1.1e-19 71.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PXF40041.1 - 2.2e-10 40.7 0.0 9.1e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Chloroa_b-bind PF00504.21 PXF40042.1 - 3.5e-05 24.4 0.1 4.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 PXF40043.1 - 0.00025 21.6 0.1 0.00029 21.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Arginosuc_synth PF00764.19 PXF40047.1 - 3.2e-147 490.9 0.0 3.8e-147 490.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 PXF40047.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 PXF40047.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase NUDIX PF00293.28 PXF40048.1 - 2.9e-05 24.1 0.0 4.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_A17 PF05380.13 PXF40056.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase Sel1 PF08238.12 PXF40057.1 - 0.001 19.7 1.0 19 6.1 0.1 5.3 6 0 0 6 6 6 2 Sel1 repeat TPR_19 PF14559.6 PXF40057.1 - 0.0088 16.5 1.5 30 5.2 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 PXF40057.1 - 0.068 13.8 0.3 11 6.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 PXF40057.1 - 0.086 13.1 0.1 9.6 6.7 0.0 3.9 4 0 0 4 4 4 0 PPR repeat HigB-like_toxin PF05015.13 PXF40058.1 - 0.066 13.6 0.1 0.075 13.4 0.1 1.0 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB VWA_2 PF13519.6 PXF40061.1 - 1e-07 32.6 0.0 5.2e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PXF40061.1 - 0.00036 20.8 0.0 0.0015 18.8 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Nitr_red_bet_C PF14711.6 PXF40061.1 - 0.064 13.0 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal Amino_oxidase PF01593.24 PXF40063.1 - 1.8e-53 182.5 0.1 2.1e-53 182.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF40063.1 - 4.1e-16 59.0 0.8 8.8e-16 57.9 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF40063.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF40063.1 - 0.00098 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PXF40063.1 - 0.0021 17.4 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 PXF40063.1 - 0.005 15.9 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 PXF40063.1 - 0.0052 16.8 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 PXF40063.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 PXF40063.1 - 0.0076 16.8 0.0 0.024 15.2 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF40063.1 - 0.013 14.6 0.2 0.022 13.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 PXF40063.1 - 0.023 13.4 0.0 0.063 12.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 PXF40063.1 - 0.23 10.5 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UCH PF00443.29 PXF40064.1 - 2.5e-48 164.8 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF40064.1 - 2.7e-14 53.5 0.1 8.4e-14 51.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PXF40064.1 - 4.6e-07 29.5 0.0 2.5e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 PXF40064.1 - 0.00035 21.0 0.0 0.03 14.8 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain DUF1090 PF06476.12 PXF40064.1 - 0.0074 16.4 4.5 0.015 15.4 4.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) Peptidase_C98 PF15499.6 PXF40064.1 - 0.037 13.5 0.4 0.08 12.4 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FYRC PF05965.14 PXF40064.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus TehB PF03848.14 PXF40065.1 - 5e-06 26.1 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 PXF40065.1 - 6.7e-06 26.0 0.0 1.4e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF40065.1 - 4.5e-05 23.3 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF40065.1 - 4.9e-05 24.0 0.0 0.00017 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40065.1 - 0.00094 19.8 0.0 0.0022 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF40065.1 - 0.0098 16.6 0.0 0.023 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF40065.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Rhodanese PF00581.20 PXF40065.1 - 0.04 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain PrmA PF06325.13 PXF40065.1 - 0.065 12.6 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SAM_MT PF04445.13 PXF40065.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase PCMT PF01135.19 PXF40065.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dimer_Tnp_hAT PF05699.14 PXF40066.1 - 1.3e-13 50.6 0.0 3.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Aldo_ket_red PF00248.21 PXF40076.1 - 4.6e-69 232.8 0.0 5.3e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 PXF40077.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 SET domain Fe_hyd_SSU PF02256.17 PXF40077.1 - 0.044 13.9 1.6 0.088 12.9 1.6 1.5 1 0 0 1 1 1 0 Iron hydrogenase small subunit Tim17 PF02466.19 PXF40078.1 - 9e-17 61.5 10.7 1.4e-16 60.8 10.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CAP_N PF01213.19 PXF40078.1 - 4 6.8 4.1 7.3 6.0 4.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ANTH PF07651.16 PXF40079.1 - 5.3e-07 28.9 0.0 1.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 ANTH domain WD40 PF00400.32 PXF40080.1 - 3.2e-52 173.3 20.9 4.4e-10 40.0 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 PXF40080.1 - 1.6e-18 66.8 9.2 1.6e-18 66.8 9.2 1.8 2 0 0 2 2 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 PXF40080.1 - 3.7e-11 43.2 0.1 0.016 15.5 0.0 5.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF40080.1 - 2.6e-09 36.8 0.0 0.0035 16.7 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 PXF40080.1 - 1.1e-05 24.3 2.6 0.017 13.8 0.2 3.9 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PXF40080.1 - 3.5e-05 22.9 0.1 0.091 11.7 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PXF40080.1 - 0.0015 18.4 0.7 9.3 6.3 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 PXF40080.1 - 0.0037 15.8 0.1 0.88 8.0 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain V_ATPase_I PF01496.19 PXF40080.1 - 0.29 9.0 10.7 0.4 8.5 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 PXF40080.1 - 0.66 8.9 10.4 1.1 8.1 10.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ABC2_membrane_3 PF12698.7 PXF40080.1 - 1.3 8.1 3.0 2.1 7.4 3.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein OmpH PF03938.14 PXF40080.1 - 1.8 8.9 25.4 3.2 8.1 25.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 PXF40080.1 - 4.7 4.6 21.8 6.3 4.2 21.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TSNAXIP1_N PF15739.5 PXF40080.1 - 5.1 7.5 13.5 7.7 6.9 3.8 2.5 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Cnd1 PF12717.7 PXF40081.1 - 1e-18 67.9 5.7 2.7e-14 53.5 0.0 5.3 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PXF40081.1 - 3.3e-14 51.8 20.2 0.33 11.3 0.1 10.3 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 PXF40081.1 - 1e-08 35.4 5.6 0.049 14.0 0.0 6.0 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 PXF40081.1 - 0.0003 21.2 17.2 0.079 13.5 0.7 8.0 10 0 0 10 10 10 1 HEAT-like repeat Adaptin_N PF01602.20 PXF40081.1 - 0.0062 15.1 0.1 0.0062 15.1 0.1 4.3 3 1 1 4 4 4 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 PXF40081.1 - 0.022 15.1 4.5 5.9 7.3 0.2 4.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF4747 PF15931.5 PXF40081.1 - 0.036 13.7 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4747) API5 PF05918.11 PXF40081.1 - 0.052 12.4 0.3 2 7.1 0.0 2.6 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) TPM_phosphatase PF04536.14 PXF40082.1 - 6.2e-06 26.4 0.0 8.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 TPM domain ELO PF01151.18 PXF40083.1 - 1e-47 162.8 28.2 1.4e-47 162.3 28.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family IFT57 PF10498.9 PXF40084.1 - 0.0011 18.0 10.1 0.0011 18.0 10.1 6.4 2 2 5 7 7 7 2 Intra-flagellar transport protein 57 ERM PF00769.19 PXF40084.1 - 0.0016 18.3 21.9 0.0016 18.3 21.9 5.8 2 1 4 6 6 6 3 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 PXF40084.1 - 0.0034 17.4 11.3 0.0034 17.4 11.3 7.2 2 1 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 PXF40084.1 - 0.0086 15.4 13.8 0.0086 15.4 13.8 7.8 2 2 6 8 8 8 3 Protein of unknown function (DUF3450) DUF4201 PF13870.6 PXF40084.1 - 4 7.1 75.4 0.35 10.6 9.6 6.8 1 1 5 6 6 6 0 Domain of unknown function (DUF4201) DnaJ PF00226.31 PXF40086.1 - 6.2e-07 29.4 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain U79_P34 PF03064.16 PXF40086.1 - 0.052 12.9 9.5 0.076 12.4 9.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIIA PF03153.13 PXF40086.1 - 0.057 13.4 7.8 0.071 13.1 7.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abi_2 PF07751.11 PXF40086.1 - 0.26 11.5 1.9 0.35 11.1 1.9 1.2 1 0 0 1 1 1 0 Abi-like protein Presenilin PF01080.17 PXF40086.1 - 0.44 9.3 6.3 0.45 9.2 6.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4554 PF15091.6 PXF40086.1 - 6.1 5.6 7.4 7.7 5.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Nop14 PF04147.12 PXF40087.1 - 4.2e-87 293.3 48.2 1.7e-48 165.6 38.7 3.1 2 1 1 3 3 3 3 Nop14-like family Myc-LZ PF02344.15 PXF40087.1 - 0.91 9.7 7.8 2.9 8.1 7.8 2.0 1 0 0 1 1 1 0 Myc leucine zipper domain DUF998 PF06197.13 PXF40088.1 - 0.0056 16.3 2.6 0.014 15.0 2.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Glyco_transf_34 PF05637.12 PXF40088.1 - 0.2 11.3 0.9 0.81 9.4 0.8 1.9 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF4199 PF13858.6 PXF40088.1 - 0.48 10.8 3.7 1.1 9.7 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) F-box-like PF12937.7 PXF40089.1 - 8.1e-11 41.6 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like SPOC PF07744.13 PXF40089.1 - 4.9e-08 33.0 0.0 9.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain F-box PF00646.33 PXF40089.1 - 1.4e-06 28.0 1.1 2.5e-06 27.2 0.0 2.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 PXF40090.1 - 1.3e-12 47.3 0.7 2.7e-12 46.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF40090.1 - 5.1e-10 39.0 0.2 8.8e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 F-box domain SPOC PF07744.13 PXF40090.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 SPOC domain Elongin_A PF06881.11 PXF40090.1 - 0.00028 21.3 0.1 0.0004 20.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Rep_fac_C PF08542.11 PXF40091.1 - 5.1e-16 58.9 0.1 7.4e-15 55.1 0.0 2.6 2 1 1 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 PXF40091.1 - 1.3e-14 54.7 0.0 2.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PXF40091.1 - 3e-12 46.6 0.0 1.9e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 PXF40091.1 - 8.3e-09 35.6 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 PXF40091.1 - 0.00019 21.7 0.8 0.41 10.9 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_7 PF12775.7 PXF40091.1 - 0.00024 20.6 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 PXF40091.1 - 0.00026 20.9 0.2 0.0011 18.8 0.1 1.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PXF40091.1 - 0.00031 20.5 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 PXF40091.1 - 0.00036 20.8 0.0 0.00086 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain DEAD PF00270.29 PXF40091.1 - 0.00052 19.8 0.2 0.014 15.2 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 PXF40091.1 - 0.00077 18.9 0.0 0.072 12.5 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 PXF40091.1 - 0.0009 19.7 0.0 0.032 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 PXF40091.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PXF40091.1 - 0.003 17.3 0.0 0.0073 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 PXF40091.1 - 0.0055 16.5 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 PXF40091.1 - 0.0066 16.4 0.6 0.13 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PXF40091.1 - 0.0081 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 PXF40091.1 - 0.021 14.8 0.0 0.16 12.0 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 PXF40091.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PXF40091.1 - 0.029 14.7 0.3 0.16 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PXF40091.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PXF40091.1 - 0.054 13.2 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 PXF40091.1 - 0.071 12.6 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 PXF40091.1 - 0.082 11.6 0.0 0.19 10.4 0.0 1.5 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.6 PXF40091.1 - 0.15 12.2 0.6 0.44 10.7 0.6 1.9 1 1 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 PXF40092.1 - 2.1e-13 50.3 0.0 3.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD PF00628.29 PXF40092.1 - 7.9e-05 22.5 7.2 7.9e-05 22.5 7.2 2.0 1 1 0 1 1 1 1 PHD-finger Ribosomal_L37e PF01907.19 PXF40092.1 - 0.0079 16.3 1.4 0.0079 16.3 1.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L37e TF_Zn_Ribbon PF08271.12 PXF40092.1 - 0.053 13.1 0.9 0.053 13.1 0.9 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Tnp_zf-ribbon_2 PF13842.6 PXF40092.1 - 0.086 13.7 1.5 0.086 13.7 1.5 2.2 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-ACC PF17848.1 PXF40092.1 - 0.13 12.3 4.3 0.6 10.2 0.7 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-RING_2 PF13639.6 PXF40092.1 - 0.2 12.0 7.0 0.4 11.0 7.0 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 PXF40092.1 - 0.44 10.5 10.3 4.5 7.3 0.9 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 PXF40092.1 - 1.8 8.2 6.5 5.6 6.6 6.0 2.1 1 1 1 2 2 2 0 PHD-finger DZR PF12773.7 PXF40092.1 - 4.6 7.3 8.5 2.5 8.2 1.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon GOLD_2 PF13897.6 PXF40093.1 - 0.29 11.6 1.9 0.23 12.0 0.2 1.6 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Tox-WTIP PF15654.6 PXF40093.1 - 2.2 8.8 8.7 1.1 9.8 0.2 3.0 2 1 1 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Takusan PF04822.13 PXF40094.1 - 0.0046 16.8 0.6 0.0082 16.0 0.6 1.4 1 0 0 1 1 1 1 Takusan MCU PF04678.13 PXF40094.1 - 0.34 11.0 3.5 0.52 10.4 3.5 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter GCN5L1 PF06320.13 PXF40094.1 - 0.37 10.9 4.7 0.15 12.2 0.8 2.0 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Caudo_TAP PF02413.17 PXF40094.1 - 1.4 9.0 5.9 4.2 7.5 5.9 1.9 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK MMR_HSR1 PF01926.23 PXF40095.1 - 2e-14 53.6 0.0 8.9e-13 48.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF40095.1 - 2e-05 24.2 0.0 0.002 17.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PXF40095.1 - 4.2e-05 23.2 0.0 0.35 10.4 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF40095.1 - 0.00075 19.4 0.0 0.053 13.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PXF40095.1 - 0.0021 18.1 0.3 0.015 15.4 0.2 2.3 1 1 2 3 3 3 1 Dynamin family DUF4724 PF15852.5 PXF40095.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) RNA_pol_A_bac PF01000.26 PXF40097.1 - 2.9e-26 92.0 0.0 4.6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PXF40097.1 - 2.7e-19 68.3 0.0 3.5e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 PXF40097.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit MMR_HSR1 PF01926.23 PXF40098.1 - 2.1e-14 53.6 0.0 8.6e-13 48.4 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF40098.1 - 2.1e-05 24.1 0.0 0.002 17.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PXF40098.1 - 4.2e-05 23.2 0.0 0.35 10.4 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF40098.1 - 0.00076 19.4 0.0 0.053 13.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PXF40098.1 - 0.0023 18.0 1.0 0.017 15.2 0.3 2.6 2 1 2 4 4 4 1 Dynamin family DUF4724 PF15852.5 PXF40098.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) F-box-like PF12937.7 PXF40099.1 - 1e-09 38.1 0.1 3.1e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like SPOC PF07744.13 PXF40099.1 - 5.2e-08 32.9 0.0 9.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 SPOC domain F-box PF00646.33 PXF40099.1 - 5.9e-06 26.0 0.6 4.4e-05 23.2 0.0 2.4 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 PXF40099.1 - 0.0058 16.5 0.1 0.0099 15.8 0.1 1.4 1 0 0 1 1 1 1 F-box bZIP_1 PF00170.21 PXF40100.1 - 2.6e-05 24.2 17.9 4.5e-05 23.5 17.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF40100.1 - 0.0016 18.5 17.4 0.0031 17.6 17.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF40100.1 - 0.12 12.9 10.8 0.36 11.4 10.8 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor ATG16 PF08614.11 PXF40100.1 - 6.4 7.0 16.1 0.44 10.8 10.2 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 PXF40101.1 - 0.0089 16.1 21.1 0.019 15.1 18.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF40101.1 - 0.066 13.3 18.7 0.047 13.8 16.5 1.9 2 0 0 2 2 2 0 Basic region leucine zipper EMP24_GP25L PF01105.24 PXF40101.1 - 0.32 10.9 1.9 7.2 6.5 1.3 2.8 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD bZIP_1 PF00170.21 PXF40102.1 - 0.022 14.8 19.4 0.043 13.9 19.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 PXF40102.1 - 0.33 11.1 19.8 0.72 10.0 18.5 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF4748 PF15932.5 PXF40102.1 - 3.3 7.5 5.1 6.5 6.6 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) bZIP_1 PF00170.21 PXF40103.1 - 0.0037 17.3 11.4 0.015 15.4 11.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF40103.1 - 0.03 14.4 11.2 0.06 13.4 11.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper zf-Tim10_DDP PF02953.15 PXF40104.1 - 3.7e-24 84.2 1.4 4.6e-24 83.8 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L27A PF00828.19 PXF40105.1 - 6.5e-30 104.4 1.7 1e-29 103.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L28e PF01778.17 PXF40106.1 - 5e-18 65.9 0.7 6e-18 65.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family SET PF00856.28 PXF40107.1 - 1.4e-09 38.5 0.0 8.5e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PXF40107.1 - 2e-05 25.3 0.0 5.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding CPSase_sm_chain PF00988.22 PXF40107.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Transglut_core PF01841.19 PXF40108.1 - 1.1e-14 54.8 0.4 2.3e-14 53.8 0.4 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_C PF00927.22 PXF40108.1 - 1.3e-13 51.0 0.0 1.4e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_N PF00868.20 PXF40108.1 - 0.00027 21.3 0.0 0.0016 18.8 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase family NPCBM_assoc PF10633.9 PXF40108.1 - 0.0044 17.2 2.9 0.82 10.0 0.1 4.6 4 2 0 4 4 4 1 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.8 PXF40108.1 - 0.0092 16.2 0.1 1 9.6 0.0 2.8 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF11 PF01345.18 PXF40108.1 - 0.88 9.9 7.3 0.56 10.6 0.4 3.3 3 2 0 3 3 3 0 Domain of unknown function DUF11 V-SNARE_C PF12352.8 PXF40109.1 - 0.14 12.4 0.4 0.34 11.2 0.4 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus AA_kinase PF00696.28 PXF40110.1 - 4.9e-32 111.4 0.1 8.2e-32 110.7 0.1 1.3 1 1 0 1 1 1 1 Amino acid kinase family SKI PF01202.22 PXF40110.1 - 0.15 12.2 1.0 2 8.5 0.3 2.8 3 0 0 3 3 3 0 Shikimate kinase RVT_2 PF07727.14 PXF40111.1 - 3.2e-29 102.3 0.0 4.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EamA PF00892.20 PXF40114.1 - 1.3e-26 93.4 33.6 3.4e-13 49.9 8.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PXF40114.1 - 0.0011 18.4 6.8 0.0011 18.4 6.8 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 PXF40114.1 - 0.0029 16.6 6.5 0.058 12.3 0.8 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Beta_propel PF09826.9 PXF40115.1 - 6.9e-122 407.9 0.0 7.9e-122 407.7 0.0 1.0 1 0 0 1 1 1 1 Beta propeller domain Crystall PF00030.19 PXF40115.1 - 0.052 13.8 0.3 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 Beta/Gamma crystallin RHS_repeat PF05593.14 PXF40116.1 - 3.2e-16 59.4 24.1 0.0022 18.5 0.0 13.9 13 3 6 19 19 19 7 RHS Repeat bMG10 PF17973.1 PXF40116.1 - 0.025 14.8 0.6 13 6.0 0.0 3.0 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF4781 PF16013.5 PXF40116.1 - 0.14 11.0 1.2 0.27 10.0 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) NB-ARC PF00931.22 PXF40121.1 - 7.9e-09 35.1 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain WD40 PF00400.32 PXF40122.1 - 1.6e-15 57.2 27.0 1.1e-05 26.0 0.0 8.4 8 2 2 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40122.1 - 1.3e-13 51.0 1.8 0.047 14.0 0.1 6.4 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 PXF40122.1 - 0.0025 17.2 0.2 0.28 10.5 0.0 3.4 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 PXF40122.1 - 0.005 16.6 9.5 0.062 13.0 0.4 4.5 4 0 0 4 4 4 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 PXF40122.1 - 0.0059 16.2 4.0 0.3 10.6 0.1 3.1 3 1 0 3 3 3 2 PQQ-like domain Hira PF07569.11 PXF40122.1 - 0.0067 16.2 0.1 0.36 10.5 0.0 3.1 3 1 0 3 3 3 1 TUP1-like enhancer of split Nup160 PF11715.8 PXF40122.1 - 0.0086 14.8 1.1 0.23 10.1 0.2 3.3 4 1 0 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PXF40122.1 - 0.04 12.9 0.4 22 3.9 0.0 4.0 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF727 PF05303.12 PXF40122.1 - 0.054 13.6 0.2 3.9 7.6 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF727) Phi_1 PF04674.12 PXF40122.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Glyco_transf_10 PF00852.19 PXF40124.1 - 0.08 12.7 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF934 PF06073.12 PXF40124.1 - 0.09 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) APH PF01636.23 PXF40126.1 - 4.6e-05 23.4 0.7 7.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pro_3_hydrox_C PF05373.11 PXF40126.1 - 0.081 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Sigma_reg_N PF13800.6 PXF40126.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Thiolase_C PF02803.18 PXF40127.1 - 1.4e-41 141.0 0.1 2e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 PXF40127.1 - 3.5e-36 124.9 0.0 4.5e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2126 PF09899.9 PXF40128.1 - 0.12 10.5 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Uma2 PF05685.12 PXF40130.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative restriction endonuclease Herpes_UL25 PF01499.16 PXF40130.1 - 0.014 13.9 0.5 0.02 13.4 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Allexi_40kDa PF05549.11 PXF40130.1 - 0.1 12.1 1.1 0.2 11.2 1.1 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Hydrolase PF00702.26 PXF40133.1 - 1.1e-11 45.4 0.6 5.9e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF40133.1 - 1.6e-05 24.7 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF40133.1 - 0.00088 19.7 0.0 0.32 11.4 0.0 2.4 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP_C PF08472.10 PXF40133.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Cation_ATPase PF13246.6 PXF40133.1 - 0.015 15.3 0.1 0.28 11.3 0.1 2.4 2 1 0 2 2 2 0 Cation transport ATPase (P-type) DUF4392 PF14336.6 PXF40133.1 - 0.1 12.1 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Flavoprotein PF02441.19 PXF40137.1 - 6.9e-52 175.4 0.0 7.9e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein TPR_12 PF13424.6 PXF40138.1 - 2e-10 40.8 1.0 0.082 13.2 0.0 4.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 PXF40138.1 - 3.2e-05 23.6 9.8 0.047 13.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF40138.1 - 0.0014 18.6 3.9 14 6.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF40138.1 - 0.0055 17.3 2.1 7.2 7.4 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF40138.1 - 0.0097 15.3 1.4 0.14 11.5 0.0 3.0 2 1 0 3 3 3 1 MalT-like TPR region Filo_VP24 PF06389.11 PXF40138.1 - 0.042 13.4 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 TPR_19 PF14559.6 PXF40138.1 - 0.088 13.3 8.1 2.5 8.7 0.1 4.6 2 1 1 4 4 4 0 Tetratricopeptide repeat Rrn6 PF10214.9 PXF40138.1 - 2.2 6.6 9.0 0.26 9.7 2.6 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Amino_oxidase PF01593.24 PXF40139.1 - 1.2e-79 268.8 0.0 1.4e-78 265.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF40139.1 - 2.1e-12 47.1 0.6 1.8e-11 44.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 PXF40139.1 - 4.2e-07 30.2 0.9 8.3e-07 29.3 0.3 1.8 2 0 0 2 2 1 1 SWIRM domain DAO PF01266.24 PXF40139.1 - 1.7e-06 27.8 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF40139.1 - 2.4e-05 23.7 0.0 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF40139.1 - 5.7e-05 23.6 0.2 0.0002 21.8 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ARID PF01388.21 PXF40139.1 - 0.00028 21.5 0.0 0.00071 20.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FAD_binding_3 PF01494.19 PXF40139.1 - 0.00041 19.7 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PXF40139.1 - 0.0005 18.9 0.1 0.00085 18.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PXF40139.1 - 0.00052 19.4 0.2 0.00052 19.4 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 PXF40139.1 - 0.0011 19.0 0.2 0.0011 19.0 0.2 2.7 3 1 0 4 4 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PXF40139.1 - 0.0025 17.2 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PXF40139.1 - 0.0083 15.4 1.8 0.013 14.7 0.2 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 PXF40139.1 - 0.026 13.6 0.5 0.046 12.8 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 PXF40139.1 - 0.037 12.4 0.0 0.063 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 PXF40139.1 - 0.23 10.5 2.7 0.15 11.1 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Transposase_21 PF02992.14 PXF40141.1 - 2.3e-12 46.6 0.0 4.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 PXF40141.1 - 0.00026 20.6 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) AATF-Che1 PF13339.6 PXF40142.1 - 0.0085 16.8 0.3 0.048 14.3 0.0 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor RNase_PH_C PF03725.15 PXF40143.1 - 3.3e-05 23.8 0.1 0.00012 22.1 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 SLS PF14611.6 PXF40143.1 - 0.098 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator W2 PF02020.18 PXF40144.1 - 2.4e-10 40.4 0.1 3.1e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4954 PF16314.5 PXF40145.1 - 0.00012 20.4 0.2 0.00017 19.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep PF00132.24 PXF40145.1 - 0.01 15.5 1.5 0.072 12.9 1.1 2.4 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 PXF40145.1 - 0.016 14.2 0.2 0.034 13.1 0.2 1.5 1 1 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 PXF40146.1 - 0.024 12.8 0.1 0.036 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PXF40146.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep PF00132.24 PXF40146.1 - 0.056 13.2 2.7 0.12 12.2 1.8 2.0 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) RNase_PH_C PF03725.15 PXF40147.1 - 6.2e-06 26.2 0.2 1.4e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 SLS PF14611.6 PXF40147.1 - 0.046 13.5 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator SLT_2 PF13406.6 PXF40147.1 - 0.14 11.4 0.1 1.1 8.5 0.1 2.0 1 1 1 2 2 2 0 Transglycosylase SLT domain T3SS_ATPase_C PF18269.1 PXF40148.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain SpecificRecomb PF10136.9 PXF40148.1 - 0.13 10.6 0.2 0.17 10.1 0.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase RuvC PF02075.17 PXF40150.1 - 0.1 12.5 1.9 0.16 11.9 1.6 1.4 1 1 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC An_peroxidase PF03098.15 PXF40151.1 - 5.2e-119 398.2 0.0 6.6e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase GRP PF07172.11 PXF40151.1 - 0.0078 16.9 0.2 0.015 15.9 0.2 1.4 1 0 0 1 1 1 1 Glycine rich protein family Sulfotransfer_1 PF00685.27 PXF40152.1 - 4e-23 82.2 0.0 1.2e-22 80.7 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PXF40152.1 - 9e-07 29.5 0.1 0.0032 17.9 0.0 3.1 1 1 1 2 2 2 2 Sulfotransferase family UQ_con PF00179.26 PXF40153.1 - 6.8e-40 136.0 0.0 8e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PXF40153.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PXF40153.1 - 0.016 15.5 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 PXF40153.1 - 0.025 14.3 0.1 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B OTU PF02338.19 PXF40154.1 - 3.1e-12 47.1 0.0 5.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease P22_CoatProtein PF11651.8 PXF40154.1 - 0.16 10.5 0.0 0.42 9.2 0.1 1.5 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 YajC PF02699.15 PXF40155.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2462 PF09495.10 PXF40156.1 - 1.1e-10 42.0 10.1 1.1e-10 42.0 10.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) zf_CCCH_4 PF18345.1 PXF40157.1 - 2.1e-12 46.7 48.1 0.00055 19.9 9.3 6.0 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 PXF40157.1 - 9.3e-11 41.4 36.8 0.0023 17.8 6.1 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PXF40157.1 - 3.9e-09 37.2 27.8 0.0082 16.8 3.2 4.6 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 PXF40157.1 - 0.00012 22.3 26.5 0.00014 22.1 7.3 3.5 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 PXF40157.1 - 0.00052 19.7 37.3 0.0043 16.8 8.5 5.3 5 1 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PXF40157.1 - 8.5 7.0 37.9 0.79 10.3 1.3 6.1 6 1 0 6 6 6 0 RNA-binding, Nab2-type zinc finger EF-hand_1 PF00036.32 PXF40158.1 - 1e-12 46.6 0.2 3.8e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PXF40158.1 - 7.5e-11 42.3 2.2 1.1e-10 41.8 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PXF40158.1 - 2.4e-10 39.5 0.4 1.5e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PXF40158.1 - 3e-09 35.9 0.0 5.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PXF40158.1 - 0.0065 16.3 0.1 4.4 7.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 PXF40158.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain TSP_NTD PF17804.1 PXF40158.1 - 4.3 7.6 5.9 38 4.5 5.9 2.2 1 1 0 1 1 1 0 Tail specific protease N-terminal domain ubiquitin PF00240.23 PXF40159.1 - 4e-24 84.2 0.0 4.8e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PXF40159.1 - 1.9e-11 43.6 0.1 2.1e-11 43.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PXF40159.1 - 3e-05 24.4 0.0 8.5e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PXF40159.1 - 9.4e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PXF40159.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 PXF40159.1 - 0.074 13.1 0.1 9.8 6.3 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain cobW PF02492.19 PXF40160.1 - 9.8e-47 158.8 0.2 1.5e-46 158.2 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PXF40160.1 - 3.7e-20 71.7 0.1 7.4e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 PXF40160.1 - 0.0098 15.8 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PXF40160.1 - 0.026 14.6 0.0 0.084 13.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PXF40160.1 - 0.042 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PXF40160.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain RR_TM4-6 PF06459.12 PXF40160.1 - 0.19 11.5 6.5 0.4 10.5 6.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_18 PF13238.6 PXF40160.1 - 0.3 11.6 2.5 0.57 10.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 PXF40160.1 - 2.6 7.2 15.7 3.9 6.6 15.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PXF40160.1 - 7.5 5.2 5.0 11 4.6 5.0 1.2 1 0 0 1 1 1 0 Presenilin SURF4 PF02077.15 PXF40161.1 - 2.5e-43 148.6 4.6 2.8e-43 148.4 4.6 1.0 1 0 0 1 1 1 1 SURF4 family DUF2975 PF11188.8 PXF40162.1 - 0.0033 17.3 1.2 0.004 17.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) DUF3611 PF12263.8 PXF40162.1 - 0.0059 16.5 1.1 0.0072 16.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) DUF1772 PF08592.11 PXF40162.1 - 0.01 16.1 0.6 0.012 15.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) MASE4 PF17158.4 PXF40162.1 - 0.019 14.2 1.1 0.022 14.1 1.1 1.1 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain tRNA_anti-like PF12869.7 PXF40162.1 - 0.083 12.5 0.7 0.12 12.0 0.7 1.5 1 1 0 1 1 1 0 tRNA_anti-like Tetraspanin PF00335.20 PXF40162.1 - 0.12 12.0 0.3 0.15 11.8 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF3493 PF11998.8 PXF40162.1 - 1.7 8.8 6.2 7.9 6.7 1.5 2.0 1 1 1 2 2 2 0 Low psii accumulation1 / Rep27 ADK PF00406.22 PXF40163.1 - 3e-59 199.5 0.0 4e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PXF40163.1 - 2.8e-24 86.1 0.4 4.7e-24 85.4 0.1 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PXF40163.1 - 1.6e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PXF40163.1 - 9.4e-07 29.1 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PXF40163.1 - 8.2e-05 23.2 0.0 0.0002 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PXF40163.1 - 0.0097 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 PXF40163.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 PXF40163.1 - 0.063 13.5 0.6 2.1 8.6 0.1 2.4 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain RuvB_N PF05496.12 PXF40163.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 PXF40163.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 PXF40163.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Thymidylate_kin PF02223.17 PXF40163.1 - 0.16 11.6 0.0 7 6.3 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Sel1 PF08238.12 PXF40165.1 - 2.4e-11 43.9 0.5 0.00019 22.0 0.2 5.2 5 0 0 5 5 5 2 Sel1 repeat NrsF PF06532.11 PXF40165.1 - 0.074 12.8 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of sigma F LRR_4 PF12799.7 PXF40166.1 - 0.00031 21.0 10.4 0.0012 19.2 2.2 5.1 3 2 2 5 5 5 1 Leucine Rich repeats (2 copies) Rep_N PF08724.10 PXF40166.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Rep protein catalytic domain like LRR_1 PF00560.33 PXF40166.1 - 0.31 11.7 11.9 21 6.2 0.1 6.5 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 PXF40166.1 - 0.39 10.5 4.4 1.8 8.4 1.7 3.7 3 2 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 PXF40166.1 - 0.52 10.5 9.1 0.27 11.4 0.3 4.9 6 0 0 6 6 6 0 Leucine Rich repeat VMA21 PF09446.10 PXF40167.1 - 1.1 9.4 5.6 11 6.2 0.2 2.7 2 0 0 2 2 2 0 VMA21-like domain Cyclase PF04199.13 PXF40169.1 - 1.4e-22 80.4 0.0 1.9e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase EB PF01683.18 PXF40170.1 - 0.0023 18.2 12.8 0.0023 18.2 12.8 2.1 2 0 0 2 2 2 1 EB module Stig1 PF04885.13 PXF40170.1 - 0.039 14.4 14.5 0.08 13.4 14.5 1.5 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Enolase_C PF00113.22 PXF40171.1 - 6.3e-142 472.1 0.2 8.7e-142 471.7 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PXF40171.1 - 9.6e-60 200.5 0.3 2.1e-59 199.4 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PXF40171.1 - 1.3e-06 28.2 0.0 3.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PXF40171.1 - 0.0048 16.1 0.2 0.0088 15.2 0.2 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Snf7 PF03357.21 PXF40172.1 - 1.9e-19 69.9 10.7 2.5e-19 69.5 10.7 1.1 1 0 0 1 1 1 1 Snf7 RCDG1 PF15725.5 PXF40172.1 - 0.042 14.3 1.3 0.085 13.3 1.3 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein DUF3292 PF11696.8 PXF40172.1 - 0.17 10.2 5.7 0.21 9.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) LUC7 PF03194.15 PXF40172.1 - 0.88 9.2 10.4 1.6 8.3 10.5 1.4 1 1 0 1 1 1 0 LUC7 N_terminus DUF737 PF05300.11 PXF40172.1 - 7.1 6.9 11.8 23 5.2 12.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Ribosomal_L13 PF00572.18 PXF40173.1 - 6.3e-48 162.1 0.4 8.6e-48 161.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Raffinose_syn PF05691.12 PXF40174.1 - 4.5e-05 21.5 0.1 7.6e-05 20.7 0.1 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_71 PF03659.14 PXF40175.1 - 0.00039 19.4 3.9 0.19 10.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 Glyco_hydro_99 PF16317.5 PXF40175.1 - 0.002 17.3 0.2 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 PXF40175.1 - 0.012 15.1 0.2 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase WbsX IGPS PF00218.21 PXF40177.1 - 5.2e-73 245.3 0.0 7e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThuA PF06283.11 PXF40177.1 - 0.036 14.3 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation DUF99 PF01949.16 PXF40178.1 - 2.1e-36 125.1 0.0 3.1e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF99 Ribosomal_S30AE PF02482.19 PXF40180.1 - 1.5e-19 70.6 3.3 6e-19 68.6 0.9 2.1 2 0 0 2 2 2 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 PXF40180.1 - 4.9e-18 64.6 0.0 9.1e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus PMC2NT PF08066.12 PXF40180.1 - 0.12 13.1 0.2 0.58 10.9 0.1 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Methyltransf_21 PF05050.12 PXF40181.1 - 2.3e-13 50.5 0.0 3.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1963 PF09234.10 PXF40182.1 - 0.0059 17.1 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) CBM_48 PF02922.18 PXF40184.1 - 0.071 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) EXOSC1 PF10447.9 PXF40187.1 - 0.0026 18.4 0.6 0.57 10.8 0.1 2.4 1 1 0 2 2 2 2 Exosome component EXOSC1/CSL4 Phytase-like PF13449.6 PXF40188.1 - 4.3e-27 95.8 0.6 4.3e-26 92.5 0.1 2.6 2 1 0 2 2 2 1 Esterase-like activity of phytase LVIVD PF08309.11 PXF40188.1 - 0.0065 15.8 0.0 0.032 13.5 0.0 2.3 2 0 0 2 2 2 1 LVIVD repeat HIT PF01230.23 PXF40189.1 - 6.2e-29 100.6 0.4 7.1e-29 100.4 0.4 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PXF40189.1 - 3.5e-21 75.8 0.4 4.1e-21 75.6 0.4 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding G5 PF07501.12 PXF40189.1 - 0.23 11.9 0.1 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 G5 domain Pkinase PF00069.25 PXF40190.1 - 4.8e-74 249.1 0.0 7.1e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40190.1 - 3.1e-40 138.1 0.0 4.6e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ApoLp-III PF07464.11 PXF40190.1 - 7.1e-10 39.2 0.0 0.00011 22.3 0.1 3.7 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) Pkinase_fungal PF17667.1 PXF40190.1 - 2.7e-05 23.1 0.3 0.00011 21.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PXF40190.1 - 0.0002 20.8 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF40190.1 - 0.00061 19.8 0.0 1 9.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF40190.1 - 0.0054 16.4 0.9 0.021 14.4 0.2 2.1 2 0 0 2 2 2 1 RIO1 family Chlorosome_CsmC PF11098.8 PXF40190.1 - 0.0084 16.1 6.8 0.0084 16.1 6.8 3.5 1 1 2 3 3 3 2 Chlorosome envelope protein C Kinase-like PF14531.6 PXF40190.1 - 0.013 14.9 0.0 0.13 11.6 0.0 2.4 1 1 1 2 2 2 0 Kinase-like DUF948 PF06103.11 PXF40190.1 - 0.019 15.2 5.1 7.7 6.8 0.1 4.1 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) PH PF00169.29 PXF40190.1 - 0.022 15.2 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 PH domain Pox_ser-thr_kin PF05445.11 PXF40190.1 - 0.029 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ATG_C PF09333.11 PXF40190.1 - 0.3 11.4 8.2 20 5.6 0.1 4.8 1 1 4 5 5 5 0 Autophagy-related protein C terminal domain MRP-S26 PF14943.6 PXF40191.1 - 5.4e-09 36.2 13.0 7.3e-09 35.8 13.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 DUF2408 PF10303.9 PXF40191.1 - 0.0086 16.6 1.3 0.011 16.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) DDE_Tnp_1_7 PF13843.6 PXF40191.1 - 0.02 14.2 0.2 0.022 14.1 0.2 1.1 1 0 0 1 1 1 0 Transposase IS4 Cauli_AT PF03233.13 PXF40191.1 - 0.15 12.0 2.4 0.17 11.8 1.8 1.4 1 1 0 1 1 1 0 Aphid transmission protein ArfGap PF01412.18 PXF40192.1 - 1.4e-32 112.2 0.6 3.1e-32 111.1 0.6 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PPE PF00823.19 PXF40192.1 - 0.04 14.0 0.4 0.04 14.0 0.4 2.2 2 0 0 2 2 2 0 PPE family DUF2514 PF10721.9 PXF40192.1 - 0.37 10.8 4.3 0.084 12.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) 2OG-FeII_Oxy_2 PF13532.6 PXF40193.1 - 1e-15 58.5 0.1 1.2e-15 58.2 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Statherin PF03875.13 PXF40193.1 - 0.026 14.6 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Statherin PMSR PF01625.21 PXF40195.1 - 8.6e-49 165.6 0.5 1.1e-48 165.3 0.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 PXF40195.1 - 2.4e-21 75.8 0.0 1e-20 73.9 0.0 2.0 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SpuA_C PF18033.1 PXF40197.1 - 0.066 13.3 0.1 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 SpuA C-terminal PAM2 PF07145.15 PXF40202.1 - 2.1e-14 52.1 2.7 0.01 15.4 0.1 4.4 4 0 0 4 4 4 4 Ataxin-2 C-terminal region PAM2 PF07145.15 PXF40203.1 - 0.041 13.6 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region tRNA-synt_1 PF00133.22 PXF40206.1 - 1.6e-41 142.3 0.0 2.5e-39 135.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 PXF40206.1 - 2.2e-06 27.3 0.0 0.00037 20.1 0.0 2.1 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 TraB PF01963.17 PXF40208.1 - 5.3e-05 23.3 0.2 8.5e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 TraB family DUF5401 PF17380.2 PXF40210.1 - 0.46 8.5 9.4 0.45 8.5 9.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Dimer_Tnp_hAT PF05699.14 PXF40211.1 - 3.5e-05 23.5 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Spc7 PF08317.11 PXF40212.1 - 0.00069 18.6 17.7 0.0073 15.2 16.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein FPP PF05911.11 PXF40212.1 - 0.0017 16.6 10.0 0.0028 15.9 10.0 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 PXF40212.1 - 0.0026 17.5 9.5 0.0038 17.0 9.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Filament PF00038.21 PXF40212.1 - 0.0027 17.3 15.4 0.065 12.8 3.5 2.0 1 1 1 2 2 2 2 Intermediate filament protein MscS_porin PF12795.7 PXF40212.1 - 0.012 15.1 15.8 0.026 14.1 15.8 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 PXF40212.1 - 0.016 15.3 9.0 0.021 14.9 9.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 PXF40212.1 - 0.032 13.1 12.4 0.039 12.8 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spectrin PF00435.21 PXF40212.1 - 0.052 14.0 12.2 0.51 10.9 3.2 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF2730 PF10805.8 PXF40212.1 - 0.054 13.6 0.9 0.11 12.6 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) KxDL PF10241.9 PXF40212.1 - 0.066 13.5 6.5 0.9 9.9 1.2 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein HemX PF04375.14 PXF40212.1 - 0.073 12.3 11.2 0.54 9.5 1.5 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc29 PF17082.5 PXF40212.1 - 0.12 12.2 8.0 0.039 13.8 2.0 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF1664 PF07889.12 PXF40212.1 - 0.12 12.4 6.1 0.87 9.6 1.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PEARLI-4 PF05278.12 PXF40212.1 - 0.16 11.6 11.2 1.2 8.7 5.7 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) HrpB7 PF09486.10 PXF40212.1 - 0.16 12.4 20.3 0.29 11.5 20.3 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Phage_int_SAM_6 PF18644.1 PXF40212.1 - 0.16 12.0 0.9 0.27 11.3 0.3 1.6 2 0 0 2 2 1 0 Phage integrase SAM-like domain BRE1 PF08647.11 PXF40212.1 - 0.26 11.4 11.8 0.2 11.8 3.6 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase YscO PF07321.12 PXF40212.1 - 0.28 11.1 24.5 0.75 9.7 15.5 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO AAA_13 PF13166.6 PXF40212.1 - 0.34 9.5 12.2 0.67 8.5 12.2 1.4 1 1 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 PXF40212.1 - 0.43 10.4 8.9 0.084 12.7 3.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 BST2 PF16716.5 PXF40212.1 - 0.43 11.2 11.6 0.95 10.1 5.3 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 PXF40212.1 - 0.44 10.1 14.1 1 8.8 14.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.11 PXF40212.1 - 0.47 10.7 19.1 7.3 6.8 19.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 PXF40212.1 - 0.63 8.5 7.8 0.81 8.2 7.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 PXF40212.1 - 0.66 10.2 7.5 1.6 8.9 1.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 PXF40212.1 - 0.7 9.9 17.5 1.8 8.6 17.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 PXF40212.1 - 0.79 9.0 15.3 0.76 9.0 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 PXF40212.1 - 0.82 9.7 18.8 1.8 8.6 16.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.18 PXF40212.1 - 0.88 10.3 8.0 0.57 10.9 0.7 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TSNAXIP1_N PF15739.5 PXF40212.1 - 1.1 9.6 9.3 0.64 10.4 2.7 2.3 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus APG6_N PF17675.1 PXF40212.1 - 1.2 9.7 17.6 5.2 7.6 17.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 PXF40212.1 - 1.2 9.8 6.8 0.65 10.7 0.3 2.7 1 1 3 4 4 3 0 SlyX BLOC1_2 PF10046.9 PXF40212.1 - 1.3 9.4 7.8 3.9 7.8 1.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 PXF40212.1 - 1.7 8.0 19.4 1.1 8.6 10.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-ZPR1 PF03367.13 PXF40212.1 - 1.8 8.4 4.8 1.7 8.5 3.4 1.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain TPR_MLP1_2 PF07926.12 PXF40212.1 - 1.9 8.6 24.2 2.2 8.4 4.1 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.11 PXF40212.1 - 2 8.4 14.4 2.4 8.2 8.3 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p GPS2_interact PF15784.5 PXF40212.1 - 3.2 8.3 11.2 2.3 8.7 3.1 2.4 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF4407 PF14362.6 PXF40212.1 - 3.9 6.7 15.6 6.6 6.0 14.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PXF40212.1 - 4.2 6.4 21.3 19 4.2 21.3 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 PXF40212.1 - 5.3 5.8 4.9 5.9 5.7 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Csm1_N PF18504.1 PXF40212.1 - 5.5 7.4 13.7 3.7 8.0 2.4 3.0 1 1 1 3 3 3 0 Csm1 N-terminal domain DUF4200 PF13863.6 PXF40212.1 - 5.7 7.4 20.5 5.1 7.5 8.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 PXF40212.1 - 6.1 6.9 21.5 1.2 9.2 6.4 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.19 PXF40212.1 - 6.6 6.4 15.6 6.9 6.3 5.0 2.6 1 1 2 3 3 3 0 GrpE Jnk-SapK_ap_N PF09744.9 PXF40212.1 - 7.8 6.7 19.6 2.7 8.2 11.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-K PF11802.8 PXF40212.1 - 8 5.9 13.9 20 4.6 12.6 1.7 1 1 0 1 1 1 0 Centromere-associated protein K Ntox47 PF15540.6 PXF40214.1 - 6.5e-22 77.9 0.3 1.2e-21 77.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial toxin 47 CBM60 PF16841.5 PXF40214.1 - 0.068 13.6 0.1 0.17 12.4 0.1 1.7 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Amidohydro_3 PF07969.11 PXF40215.1 - 2.2e-05 24.1 0.0 2.8e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PXF40215.1 - 0.0034 16.8 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family VWA_2 PF13519.6 PXF40216.1 - 0.00084 20.0 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PXF40216.1 - 0.0037 17.5 0.0 0.0052 17.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Acetyltransf_3 PF13302.7 PXF40217.1 - 0.0062 17.2 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UDPGT PF00201.18 PXF40217.1 - 0.044 12.6 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Acetyltransf_1 PF00583.25 PXF40217.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HAP2-GCS1 PF10699.9 PXF40217.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Male gamete fusion factor Per1 PF04080.13 PXF40218.1 - 0.15 11.8 0.5 0.18 11.5 0.5 1.0 1 0 0 1 1 1 0 Per1-like family Glyco_hydro_31 PF01055.26 PXF40219.1 - 2.6e-72 244.4 2.6 3.5e-72 244.0 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 PXF40219.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 PXF40219.1 - 0.058 13.7 1.7 0.2 12.0 1.7 2.1 1 0 0 1 1 1 0 Galactose mutarotase-like zf-C2H2 PF00096.26 PXF40222.1 - 6e-11 42.2 10.9 0.00035 20.9 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF40222.1 - 4.9e-10 39.4 12.5 0.0052 17.5 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF40222.1 - 1.3e-05 25.9 6.3 0.00033 21.3 1.3 2.9 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 PXF40222.1 - 0.00017 21.8 20.4 0.00098 19.5 0.5 5.5 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2HE PF16278.5 PXF40222.1 - 0.00021 21.7 4.1 3.1 8.3 0.1 3.5 2 1 1 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met2 PF12907.7 PXF40222.1 - 0.0027 17.8 0.2 0.0027 17.8 0.2 2.8 3 0 0 3 3 2 1 Zinc-binding Actin_micro PF17003.5 PXF40222.1 - 0.003 16.8 5.4 0.38 9.9 0.5 2.4 1 1 2 3 3 3 2 Putative actin-like family zf-Di19 PF05605.12 PXF40222.1 - 0.0051 17.1 7.8 0.72 10.2 0.2 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 PXF40222.1 - 0.0061 16.3 6.7 0.56 10.0 0.2 4.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 PXF40222.1 - 0.0075 15.8 2.3 1.2 8.7 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type BolA PF01722.18 PXF40222.1 - 0.0085 16.4 4.3 0.016 15.5 0.2 2.7 2 0 0 2 2 2 1 BolA-like protein OrfB_Zn_ribbon PF07282.11 PXF40222.1 - 0.07 13.1 7.4 1.2 9.1 0.4 3.4 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.8 PXF40222.1 - 0.085 13.2 0.0 0.085 13.2 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PXF40222.1 - 0.64 9.9 4.2 9.5 6.1 0.2 2.8 1 1 1 2 2 2 0 GAGA factor TFIIE-A_C PF11521.8 PXF40222.1 - 0.7 10.2 6.5 0.52 10.6 0.5 3.0 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha LIM PF00412.22 PXF40222.1 - 0.95 9.7 5.0 11 6.4 0.1 2.9 2 1 0 2 2 2 0 LIM domain C1_2 PF03107.16 PXF40222.1 - 1 9.7 4.7 28 5.1 0.1 3.0 3 0 0 3 3 3 0 C1 domain FYDLN_acid PF09538.10 PXF40222.1 - 1.9 9.2 7.5 0.64 10.7 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.7 PXF40222.1 - 6.3 7.3 8.9 0.39 11.2 0.2 3.3 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PXF40222.1 - 6.7 6.8 10.7 1.1 9.4 0.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger SNARE PF05739.19 PXF40223.1 - 2.7e-11 43.3 0.4 6.6e-11 42.0 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 PXF40223.1 - 3.9e-06 25.9 0.6 1.2e-05 24.3 0.6 1.9 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 PXF40223.1 - 4e-06 26.6 5.7 0.00019 21.2 0.0 2.7 2 1 1 3 3 3 1 Syntaxin DUF16 PF01519.16 PXF40223.1 - 0.0044 17.5 2.3 0.029 14.8 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function DUF16 ALMT PF11744.8 PXF40223.1 - 0.029 13.2 0.9 0.065 12.1 0.2 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter UPF0242 PF06785.11 PXF40223.1 - 0.051 13.7 3.8 1.4 9.0 2.0 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1930 PF09122.10 PXF40223.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1930) Baculo_PEP_C PF04513.12 PXF40223.1 - 0.13 12.3 5.6 3.2 7.8 0.7 2.6 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PXF40223.1 - 0.15 12.1 6.8 1.1 9.3 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SF-assemblin PF06705.11 PXF40223.1 - 0.16 11.3 2.2 1.5 8.1 0.2 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin HrpB2 PF09487.10 PXF40223.1 - 0.16 12.4 4.0 0.74 10.3 0.2 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) 7TMR-HDED PF07697.11 PXF40223.1 - 0.2 11.8 3.4 0.55 10.3 3.4 1.9 1 1 0 1 1 1 0 7TM-HD extracellular Syntaxin_2 PF14523.6 PXF40223.1 - 0.21 11.9 5.8 2 8.8 0.8 2.9 2 1 1 3 3 3 0 Syntaxin-like protein DUF1043 PF06295.12 PXF40223.1 - 0.29 11.2 3.0 0.52 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Snapin_Pallidin PF14712.6 PXF40223.1 - 0.29 11.6 3.4 1.3 9.5 0.8 2.5 2 0 0 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.12 PXF40223.1 - 1.4 9.5 7.6 2 8.9 0.4 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TBCC_N PF16752.5 PXF40223.1 - 1.7 9.1 5.9 10 6.6 0.4 2.9 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain TAP42 PF04177.12 PXF40224.1 - 7.6e-61 206.0 10.0 9.4e-61 205.7 10.0 1.0 1 0 0 1 1 1 1 TAP42-like family DUF572 PF04502.13 PXF40224.1 - 0.073 12.7 9.9 0.11 12.1 9.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.11 PXF40224.1 - 0.085 12.9 6.6 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region FYDLN_acid PF09538.10 PXF40224.1 - 5.6 7.7 11.4 9.1 7.0 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) VSG_B PF13206.6 PXF40224.1 - 6.6 5.9 7.4 6.5 5.9 0.3 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain FmiP_Thoc5 PF09766.9 PXF40224.1 - 6.7 5.9 11.5 0.18 11.1 3.1 2.0 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 SAC3_GANP PF03399.16 PXF40225.1 - 3.7e-11 43.0 0.8 5.5e-11 42.4 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PXF40225.1 - 0.022 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family DUF2145 PF09916.9 PXF40225.1 - 0.095 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) DUF3337 PF11816.8 PXF40226.1 - 2.7e-31 108.7 0.0 4.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 PXF40226.1 - 2.1e-18 66.3 19.8 1.1e-05 26.1 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40226.1 - 0.00073 19.8 0.2 0.12 12.7 0.1 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RAWUL PF16207.5 PXF40226.1 - 0.002 18.8 0.0 0.0043 17.7 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Nucleoporin_N PF08801.11 PXF40226.1 - 0.018 13.8 0.1 3.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 PXF40226.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain DUF4611 PF15387.6 PXF40227.1 - 0.18 12.0 3.2 11 6.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Miff PF05644.11 PXF40227.1 - 6.5 6.3 9.7 0.16 11.5 2.6 1.9 2 1 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff RRM_1 PF00076.22 PXF40228.1 - 3.2e-10 39.7 0.0 1.4e-07 31.3 0.1 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ada3 PF10198.9 PXF40229.1 - 6.2 7.0 10.0 26 5.0 10.0 2.0 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 bZIP_1 PF00170.21 PXF40230.1 - 1.1e-09 38.3 2.9 1.8e-09 37.6 2.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF40230.1 - 3.4e-09 36.7 5.3 6e-09 35.9 5.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper IpaC_SipC PF09599.10 PXF40230.1 - 0.076 12.5 0.2 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) SdpA PF17418.2 PXF40230.1 - 0.099 12.5 0.4 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 Sporulation delaying protein SdpA AAA_32 PF13654.6 PXF40233.1 - 0.044 12.6 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain zf-H3C2 PF16721.5 PXF40233.1 - 0.12 12.7 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding VWA PF00092.28 PXF40234.1 - 3.6e-17 63.2 0.0 4.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF40234.1 - 7.4e-07 29.8 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF40234.1 - 0.0006 19.1 0.0 0.0045 16.2 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) HEPN_MAE_28990 PF18737.1 PXF40234.1 - 0.22 11.4 0.0 0.96 9.3 0.0 1.8 2 0 0 2 2 2 0 MAE_28990/MAE_18760-like HEPN VWA PF00092.28 PXF40235.1 - 2.8e-11 44.0 0.0 3.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF40235.1 - 2.2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Fringe PF02434.16 PXF40236.1 - 3.4e-08 33.3 0.0 4.6e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Fringe-like Glyco_tranf_2_3 PF13641.6 PXF40236.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Tom22 PF04281.13 PXF40237.1 - 1.6e-06 27.9 0.2 2e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 VMA21 PF09446.10 PXF40237.1 - 6.6 6.9 6.9 5.2 7.3 0.2 2.8 2 1 0 2 2 2 0 VMA21-like domain Hint PF01079.20 PXF40238.1 - 5.6e-21 75.0 0.1 1.1e-20 74.1 0.1 1.4 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 PXF40238.1 - 0.13 12.5 0.0 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 Pretoxin HINT domain TFIIF_alpha PF05793.12 PXF40238.1 - 1.6 7.2 23.7 2.3 6.7 23.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Tim54 PF11711.8 PXF40238.1 - 3.4 6.3 4.5 5.6 5.7 4.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRA1 PF03208.19 PXF40239.1 - 3.9e-31 107.6 3.0 5.5e-31 107.1 3.0 1.2 1 0 0 1 1 1 1 PRA1 family protein Pex24p PF06398.11 PXF40239.1 - 6.8 5.6 9.4 1 8.2 5.6 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DEAD PF00270.29 PXF40240.1 - 7.2e-48 162.7 0.1 1.2e-47 161.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF40240.1 - 1.7e-29 102.4 0.1 2.5e-27 95.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PXF40240.1 - 2.2e-09 37.6 0.9 6.3e-09 36.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Vac_ImportDeg PF09783.9 PXF40241.1 - 5.3e-36 123.9 0.1 5.9e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein OCRE PF17780.1 PXF40241.1 - 0.07 13.2 1.7 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 OCRE domain TRAP-gamma PF07074.12 PXF40242.1 - 3.4e-11 43.0 3.6 2.9e-06 26.9 0.1 2.0 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) Phage_holin_3_6 PF07332.11 PXF40242.1 - 0.041 13.9 0.2 0.041 13.9 0.2 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III INSIG PF07281.12 PXF40243.1 - 0.012 15.2 5.9 0.19 11.3 5.9 2.4 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) zf_C2H2_6 PF18450.1 PXF40243.1 - 0.32 10.7 2.7 0.56 10.0 2.7 1.4 1 0 0 1 1 1 0 Zinc Finger domain Sep15_SelM PF08806.11 PXF40244.1 - 1e-14 54.5 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain Malectin PF11721.8 PXF40247.1 - 2.6e-24 86.2 0.0 1.2e-14 54.7 0.0 3.1 3 0 0 3 3 3 2 Malectin domain TIG PF01833.24 PXF40247.1 - 4.9e-12 45.8 20.8 7.9e-08 32.3 3.8 4.2 4 0 0 4 4 4 2 IPT/TIG domain GSDH PF07995.11 PXF40247.1 - 7.3e-05 22.2 0.0 0.0052 16.1 0.0 2.3 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase Malectin_like PF12819.7 PXF40247.1 - 0.093 11.9 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Malectin-like domain Ustilago_mating PF05722.12 PXF40248.1 - 2.6 7.5 7.6 3.6 7.0 7.6 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Abhydrolase_1 PF00561.20 PXF40249.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF40249.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 PXF40249.1 - 0.082 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 TAP-like protein Bestrophin PF01062.21 PXF40250.1 - 7e-11 42.1 0.0 7.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TB2_DP1_HVA22 PF03134.19 PXF40250.1 - 0.02 14.8 1.2 0.02 14.8 1.2 1.7 1 1 1 2 2 2 0 TB2/DP1, HVA22 family CAP PF00188.26 PXF40251.1 - 6.4e-11 43.2 1.3 1e-10 42.5 1.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.17 PXF40251.1 - 0.00088 19.3 4.7 0.0012 18.8 4.7 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1727 PF08353.10 PXF40252.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) CASP_C PF08172.12 PXF40256.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 CASP C terminal NAM-associated PF14303.6 PXF40259.1 - 9.2e-06 26.5 3.5 1.6e-05 25.7 3.5 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain PNKP-ligase_C PF16536.5 PXF40259.1 - 0.074 13.3 2.0 0.34 11.2 0.2 2.2 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Trypsin PF00089.26 PXF40260.1 - 1.6e-33 116.4 0.0 1.9e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF40260.1 - 1.7e-06 29.0 0.1 3.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain GTP1_OBG PF01018.22 PXF40261.1 - 5.3e-25 87.8 0.8 1.1e-24 86.8 0.8 1.6 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 PXF40261.1 - 2.7e-22 79.0 0.0 4.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF40261.1 - 1.2e-07 31.4 0.0 6.6e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 PXF40261.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 PXF40261.1 - 0.01 15.6 0.0 2.6 7.8 0.0 2.8 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PXF40261.1 - 0.069 13.7 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PXF40261.1 - 0.17 11.9 0.0 6.4 6.8 0.1 2.2 1 1 0 2 2 2 0 Dynamin family Macoilin PF09726.9 PXF40263.1 - 0.0066 15.1 9.3 0.0082 14.8 9.3 1.1 1 0 0 1 1 1 1 Macoilin family USP8_interact PF08941.10 PXF40263.1 - 0.015 15.2 2.8 0.021 14.6 2.8 1.4 1 0 0 1 1 1 0 USP8 interacting DUF3584 PF12128.8 PXF40263.1 - 0.021 12.4 11.0 0.029 11.9 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 PXF40263.1 - 0.036 13.3 8.4 0.046 13.0 8.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein SKA1 PF07160.12 PXF40263.1 - 0.058 13.2 4.4 0.083 12.7 4.4 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Fez1 PF06818.15 PXF40263.1 - 0.061 13.8 12.4 0.12 12.8 12.4 1.4 1 0 0 1 1 1 0 Fez1 ATG16 PF08614.11 PXF40263.1 - 0.062 13.5 17.2 0.34 11.1 7.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 PXF40263.1 - 0.083 12.0 6.9 0.11 11.5 6.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 PXF40263.1 - 0.11 12.5 15.9 1.2 9.2 1.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2071 PF09844.9 PXF40263.1 - 0.17 11.5 1.2 0.23 11.0 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) FlxA PF14282.6 PXF40263.1 - 0.27 11.3 9.2 3.7 7.6 8.9 2.4 1 1 1 2 2 2 0 FlxA-like protein Exonuc_VII_L PF02601.15 PXF40263.1 - 0.27 10.7 3.2 0.36 10.4 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 PXF40263.1 - 0.46 8.3 4.2 0.57 8.0 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.9 PXF40263.1 - 0.57 8.8 5.3 0.85 8.2 5.3 1.2 1 0 0 1 1 1 0 Peptidase S46 SpecificRecomb PF10136.9 PXF40263.1 - 0.67 8.2 2.3 0.91 7.8 2.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF2203 PF09969.9 PXF40263.1 - 1.1 10.0 8.1 2.2 9.0 4.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SlyX PF04102.12 PXF40263.1 - 1.1 9.9 10.8 5.8 7.6 1.1 3.3 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 PXF40263.1 - 1.7 8.7 19.3 7.4 6.6 17.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 PXF40263.1 - 1.9 9.0 11.5 5.3 7.5 2.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 PXF40263.1 - 2.2 6.8 4.5 3.5 6.1 4.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 PXF40263.1 - 3.1 7.9 14.6 2.2 8.4 6.5 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 PXF40263.1 - 3.4 8.3 9.8 3.3 8.3 4.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DASH_Spc19 PF08287.11 PXF40263.1 - 4.6 7.1 15.4 3 7.7 0.6 2.1 1 1 1 2 2 2 0 Spc19 UPF0242 PF06785.11 PXF40263.1 - 5.2 7.1 11.5 2.5 8.2 9.4 1.5 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 PXF40263.1 - 5.3 7.7 12.5 1.2e+02 3.4 11.9 2.6 2 1 0 2 2 1 0 Initiation control protein YabA Cnn_1N PF07989.11 PXF40263.1 - 5.9 7.1 17.4 1.6 8.9 0.8 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 PXF40263.1 - 7.9 5.3 16.6 20 3.9 16.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 PXF40263.1 - 9.1 6.6 7.2 4.8 7.5 0.6 2.8 3 0 0 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 PXF40263.1 - 9.3 6.7 7.8 73 3.9 3.8 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Aa_trans PF01490.18 PXF40265.1 - 8e-32 110.4 25.3 9.7e-32 110.2 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2512 PF10710.9 PXF40265.1 - 3.9 7.1 10.7 0.087 12.5 2.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2512) Pro_isomerase PF00160.21 PXF40266.1 - 1.3e-32 113.2 0.0 3.6e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COQ9 PF08511.11 PXF40266.1 - 0.03 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 COQ9 YL1 PF05764.13 PXF40266.1 - 2.1 8.4 30.5 0.014 15.5 17.5 2.1 1 1 1 2 2 2 0 YL1 nuclear protein GCIP PF13324.6 PXF40266.1 - 3 7.4 9.0 3.8 7.1 1.4 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting SCIMP PF15050.6 PXF40266.1 - 3.4 8.1 4.1 4.7 7.7 1.5 2.2 2 0 0 2 2 2 0 SCIMP protein ACI44 PF15270.6 PXF40267.1 - 0.37 11.0 11.8 0.9 9.8 8.4 2.9 2 1 0 2 2 2 0 Metallo-carboxypeptidase inhibitor WAP PF00095.21 PXF40267.1 - 6.6 7.2 31.2 0.88 10.0 0.1 4.0 3 1 1 4 4 4 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CarbpepA_inh PF02977.15 PXF40267.1 - 8.5 6.3 15.9 23 4.9 5.1 3.7 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor Cadherin_C_2 PF16492.5 PXF40268.1 - 0.098 13.4 0.8 4.7 8.0 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal SET PF00856.28 PXF40272.1 - 0.0002 21.8 0.0 0.01 16.2 0.0 2.2 1 1 1 2 2 2 2 SET domain 2-Hacid_dh_C PF02826.19 PXF40273.1 - 7.9e-40 136.1 0.0 1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PXF40273.1 - 2.6e-05 24.5 0.0 4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 PXF40273.1 - 0.031 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_2 PF12706.7 PXF40273.1 - 0.062 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Fer2_4 PF13510.6 PXF40273.1 - 0.18 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Amino_oxidase PF01593.24 PXF40274.1 - 1.1e-22 81.0 0.1 6.2e-21 75.2 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF40274.1 - 1.4e-10 41.2 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF40274.1 - 0.0011 18.6 0.0 0.0028 17.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF40274.1 - 0.0074 16.3 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 PXF40274.1 - 0.0079 14.9 0.1 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 PXF40274.1 - 0.038 13.2 0.1 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 PXF40274.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF40274.1 - 0.35 9.9 1.5 0.36 9.9 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain E1-E2_ATPase PF00122.20 PXF40277.1 - 1.3e-50 171.4 0.3 1.3e-50 171.4 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 PXF40277.1 - 1.6e-37 127.8 1.7 4.2e-15 55.9 0.0 4.1 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase PF00702.26 PXF40277.1 - 4.4e-32 112.1 1.2 1.6e-31 110.3 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF40277.1 - 0.022 14.5 0.4 0.089 12.5 0.3 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VbhA PF18495.1 PXF40278.1 - 0.033 14.1 0.4 0.085 12.7 0.4 1.7 1 0 0 1 1 1 0 Antitoxin VbhA WD40 PF00400.32 PXF40282.1 - 2.5e-57 189.5 36.4 3.8e-09 37.0 1.9 9.7 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40282.1 - 8.4e-31 106.1 15.4 4.5e-06 26.9 0.1 9.0 2 1 7 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF40282.1 - 3.1e-15 56.1 1.7 4.7e-15 55.5 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain Ge1_WD40 PF16529.5 PXF40282.1 - 2.1e-06 26.9 3.0 4.8 6.0 0.0 6.6 2 1 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF40282.1 - 7.2e-05 21.6 8.8 1.6 7.2 0.0 7.0 8 0 0 8 8 8 2 Nucleoporin Nup120/160 PD40 PF07676.12 PXF40282.1 - 0.00012 21.9 0.0 25 4.9 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 PXF40282.1 - 0.0013 19.1 1.2 35 5.1 0.0 5.3 3 1 1 4 4 4 0 PQQ-like domain AAA_22 PF13401.6 PXF40282.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Peptidase_S9_N PF02897.15 PXF40282.1 - 0.059 12.2 15.5 3.2 6.4 0.1 5.7 3 1 2 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain HAUS-augmin3 PF14932.6 PXF40282.1 - 0.1 12.1 4.1 0.19 11.3 4.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Exonuc_VII_L PF02601.15 PXF40282.1 - 0.14 11.7 0.4 0.26 10.8 0.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit APAF1_C PF17908.1 PXF40282.1 - 0.18 11.8 1.4 0.43 10.6 0.1 2.3 3 0 0 3 3 3 0 APAF-1 helical domain Nbas_N PF15492.6 PXF40282.1 - 0.58 9.4 15.0 9.2 5.5 0.1 5.2 2 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal SAP130_C PF16014.5 PXF40283.1 - 0.16 11.1 1.8 0.17 10.9 1.8 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Herpes_gp2 PF05955.11 PXF40286.1 - 0.038 13.5 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Toxin_11 PF07473.11 PXF40289.1 - 0.13 12.3 6.0 0.24 11.5 2.4 3.6 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species DUF2407_C PF13373.6 PXF40290.1 - 0.065 13.4 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF4577 PF15145.6 PXF40290.1 - 0.25 11.4 1.0 1.1 9.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) PI-PLC-X PF00388.19 PXF40292.1 - 1.7e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4294 PF14127.6 PXF40292.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) CH PF00307.31 PXF40295.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Mating_N PF12731.7 PXF40295.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.7 2 0 0 2 2 2 0 Mating-type protein beta 1 RVT_2 PF07727.14 PXF40296.1 - 8.2e-08 32.2 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TTR-52 PF01060.23 PXF40297.1 - 0.0049 17.5 0.0 0.015 16.0 0.0 1.9 1 0 0 1 1 1 1 Transthyretin-like family adh_short PF00106.25 PXF40298.1 - 3.3e-15 56.1 0.0 4.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF40298.1 - 2.9e-08 33.6 0.0 3.3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RCC1 PF00415.18 PXF40300.1 - 0.00025 21.6 0.0 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat SET PF00856.28 PXF40303.1 - 0.00039 20.9 0.0 0.00055 20.4 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF2686 PF10887.8 PXF40304.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) AbrB-like PF14250.6 PXF40306.1 - 0.04 14.0 0.3 0.086 12.9 0.0 1.8 2 0 0 2 2 2 0 AbrB-like transcriptional regulator Hint PF01079.20 PXF40307.1 - 1e-29 103.6 0.1 1.9e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Hint module Fasciclin PF02469.22 PXF40307.1 - 3.8e-11 43.3 0.4 2.1e-10 40.9 0.1 2.3 2 1 0 2 2 2 1 Fasciclin domain Intein_splicing PF14890.6 PXF40307.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Intein splicing domain Vint PF14623.6 PXF40307.1 - 0.049 13.4 0.1 1.3 8.8 0.0 2.4 1 1 1 2 2 2 0 Hint-domain PT-HINT PF07591.11 PXF40307.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain DUF2457 PF10446.9 PXF40307.1 - 0.38 9.8 11.4 0.54 9.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) OAD_gamma PF04277.13 PXF40307.1 - 0.49 11.0 0.1 0.49 11.0 0.1 2.4 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cwf_Cwc_15 PF04889.12 PXF40307.1 - 5.5 6.7 8.3 9.3 5.9 8.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ArfGap PF01412.18 PXF40308.1 - 1.9e-10 40.8 1.6 2.7e-10 40.4 1.4 1.3 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.6 PXF40308.1 - 0.011 15.6 1.1 0.014 15.2 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 PXF40308.1 - 0.036 14.0 0.7 0.047 13.6 0.7 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NinF PF05810.12 PXF40308.1 - 0.72 9.8 3.6 0.58 10.1 1.0 1.9 1 1 1 2 2 2 0 NinF protein zf-dskA_traR PF01258.17 PXF40308.1 - 1.4 8.9 3.9 16 5.6 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DNA_pol_delta_4 PF04081.13 PXF40309.1 - 3.8e-19 69.3 0.2 8.3e-19 68.2 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Mito_carr PF00153.27 PXF40310.1 - 3.5e-52 174.3 7.4 2.7e-23 81.7 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF40310.1 - 8.3e-06 25.2 1.2 0.0039 16.4 0.0 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease DUF4646 PF15496.6 PXF40310.1 - 0.052 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) HTH_3 PF01381.22 PXF40311.1 - 1.3e-14 54.0 0.3 2e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 PXF40311.1 - 3.3e-08 33.9 10.3 1.9e-07 31.5 4.0 3.2 2 2 0 2 2 2 1 Multiprotein bridging factor 1 HTH_19 PF12844.7 PXF40311.1 - 4.9e-06 26.5 0.1 7.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 PXF40311.1 - 1.1e-05 25.7 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 PXF40311.1 - 0.0065 16.4 0.4 0.0098 15.8 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 PXF40311.1 - 0.0071 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 PXF40311.1 - 0.15 11.8 0.0 0.62 9.9 0.0 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain Ribosomal_S13_N PF08069.12 PXF40312.1 - 1.2e-30 105.3 0.1 2.3e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 PXF40312.1 - 4e-14 52.6 1.3 6.1e-14 52.0 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 1-cysPrx_C PF10417.9 PXF40312.1 - 0.19 11.6 0.4 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Peptidase_A22B PF04258.13 PXF40313.1 - 1.9e-54 185.1 16.3 2.6e-54 184.7 16.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Sec23_trunk PF04811.15 PXF40314.1 - 7.7e-57 192.6 0.0 1.1e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PXF40314.1 - 7.6e-27 93.9 0.0 1.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PXF40314.1 - 2e-24 85.4 0.4 3.6e-24 84.5 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PXF40314.1 - 2.5e-13 49.8 7.5 6.1e-13 48.6 7.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PXF40314.1 - 1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 PXF40314.1 - 0.12 13.0 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Fis1_TPR_C PF14853.6 PXF40315.1 - 2.1e-17 62.9 0.1 3.3e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 PXF40315.1 - 3.1e-10 39.6 0.0 6.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 PXF40315.1 - 2.3e-05 24.1 0.1 0.00012 21.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PXF40315.1 - 0.019 15.5 0.1 0.073 13.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DTW PF03942.15 PXF40316.1 - 6.5e-26 91.3 0.2 8.9e-26 90.8 0.2 1.2 1 0 0 1 1 1 1 DTW domain SDA1 PF05285.12 PXF40317.1 - 6.2e-53 180.4 47.8 2.8e-34 119.1 16.1 3.1 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 PXF40317.1 - 3.9e-08 33.5 0.0 1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain RRN3 PF05327.11 PXF40317.1 - 4.3 5.7 13.0 7.7 4.9 8.3 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 NifU PF01106.17 PXF40318.1 - 3.6e-33 113.5 0.3 3.4e-25 88.0 0.1 2.2 2 0 0 2 2 2 2 NifU-like domain dUTPase PF00692.19 PXF40320.1 - 6.4e-43 145.5 0.0 9.6e-43 144.9 0.0 1.3 1 0 0 1 1 1 1 dUTPase ABC_tran PF00005.27 PXF40321.1 - 1.7e-36 125.8 0.0 6.8e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 PXF40321.1 - 4.7e-13 48.7 3.8 1.2e-12 47.4 3.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 PXF40321.1 - 1e-10 41.4 5.6 0.00098 18.6 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PXF40321.1 - 6.5e-10 39.3 3.9 0.34 10.7 0.0 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 PXF40321.1 - 3.7e-07 29.7 3.4 3.7e-07 29.7 3.4 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.29 PXF40321.1 - 1.3e-05 25.7 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PXF40321.1 - 3.5e-05 23.7 0.1 0.47 10.1 0.0 2.9 2 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 PXF40321.1 - 5.6e-05 23.1 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PXF40321.1 - 0.00015 22.2 0.0 0.62 10.4 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PXF40321.1 - 0.00029 20.5 0.4 0.77 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 PXF40321.1 - 0.00057 19.9 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_7 PF12838.7 PXF40321.1 - 0.00063 20.3 0.2 0.00063 20.3 0.2 2.6 3 0 0 3 3 2 1 4Fe-4S dicluster domain NACHT PF05729.12 PXF40321.1 - 0.00074 19.5 0.3 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 PXF40321.1 - 0.0008 19.4 0.0 0.037 14.0 0.0 2.6 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PXF40321.1 - 0.00094 19.7 1.6 0.078 13.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 PXF40321.1 - 0.00097 19.1 3.0 0.00097 19.1 3.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 PXF40321.1 - 0.0013 19.0 0.5 0.41 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 PXF40321.1 - 0.0024 17.9 1.0 0.0024 17.9 1.0 2.6 2 1 1 3 3 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 PXF40321.1 - 0.0025 18.0 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF40321.1 - 0.0029 17.3 1.6 1.2 8.8 0.0 3.1 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 PXF40321.1 - 0.004 16.8 1.1 0.3 10.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 PXF40321.1 - 0.005 16.4 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_9 PF13187.6 PXF40321.1 - 0.0078 16.4 8.8 0.0078 16.4 8.8 2.1 2 1 0 2 2 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 PXF40321.1 - 0.008 15.9 1.1 0.61 9.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 PXF40321.1 - 0.0083 16.2 0.9 0.0083 16.2 0.9 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain RNA_helicase PF00910.22 PXF40321.1 - 0.01 16.2 0.0 3.1 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 PXF40321.1 - 0.012 15.7 0.4 1.6 8.8 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Fer4_16 PF13484.6 PXF40321.1 - 0.013 16.4 0.2 0.013 16.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Thymidylate_kin PF02223.17 PXF40321.1 - 0.013 15.2 0.0 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase MMR_HSR1 PF01926.23 PXF40321.1 - 0.019 15.1 0.8 9.8 6.3 0.0 3.0 3 1 0 3 3 2 0 50S ribosome-binding GTPase Fer4_21 PF14697.6 PXF40321.1 - 0.02 15.0 12.6 0.02 15.0 12.6 2.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.6 PXF40321.1 - 0.024 14.9 0.6 3.5 7.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 PXF40321.1 - 0.031 14.8 0.0 2.7 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PXF40321.1 - 0.057 12.6 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 PXF40321.1 - 0.091 12.2 1.0 6.4 6.1 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein Zeta_toxin PF06414.12 PXF40321.1 - 0.14 11.4 1.9 1.8 7.8 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin GCHY-1 PF02649.14 PXF40321.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Fer4_8 PF13183.6 PXF40321.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Roc PF08477.13 PXF40321.1 - 0.22 11.7 0.5 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 PXF40321.1 - 2.2 8.2 5.7 24 4.8 0.0 4.1 5 0 0 5 5 5 0 NTPase DUF4646 PF15496.6 PXF40322.1 - 0.043 14.4 0.0 0.054 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Sec34 PF04136.15 PXF40323.1 - 1.4e-25 89.9 0.0 2.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 PXF40323.1 - 1.2 9.5 4.5 4 7.8 0.3 3.6 4 0 0 4 4 4 0 Phasin protein NYD-SP28 PF14772.6 PXF40323.1 - 6.3 6.9 6.5 1.1 9.3 2.3 1.9 2 0 0 2 2 2 0 Sperm tail DUF383 PF04063.14 PXF40324.1 - 9.5e-12 45.0 0.2 4.6e-11 42.7 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 PXF40324.1 - 1.1e-08 34.7 0.0 3.8e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Arm PF00514.23 PXF40324.1 - 0.23 11.6 7.9 4.8 7.4 0.1 4.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat NuA4 PF09340.10 PXF40325.1 - 3.6e-15 55.6 0.0 9.3e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF812 PF05667.11 PXF40325.1 - 0.028 13.3 4.5 0.036 13.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ASD2 PF08687.11 PXF40325.1 - 1.7 8.2 6.7 2.4 7.7 6.0 1.6 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 ABC_tran_CTD PF16326.5 PXF40325.1 - 2 8.7 6.5 1.3 9.3 1.9 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Rubredoxin PF00301.20 PXF40326.1 - 1.7e-18 66.4 4.6 2.6e-18 65.8 4.6 1.3 1 0 0 1 1 1 1 Rubredoxin IBR PF01485.21 PXF40326.1 - 0.023 14.9 0.1 0.047 13.9 0.1 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 PXF40326.1 - 0.03 14.8 3.5 0.19 12.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 PXF40326.1 - 0.05 13.7 4.3 0.46 10.7 4.3 2.4 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 PXF40326.1 - 0.05 13.6 0.3 0.079 13.0 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PXF40326.1 - 0.073 13.1 1.7 0.69 10.0 1.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 PXF40326.1 - 0.08 12.9 0.8 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-HIT PF04438.16 PXF40326.1 - 0.19 11.6 5.1 1.8 8.5 0.8 2.3 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_2 PF13240.6 PXF40326.1 - 0.26 11.1 4.1 7.7 6.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 PXF40326.1 - 0.47 10.4 6.0 6.9 6.7 6.0 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain RNA_POL_M_15KD PF02150.16 PXF40326.1 - 8.1 6.4 6.2 1.5 8.7 0.6 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit KIX_2 PF16987.5 PXF40327.1 - 1.3e-11 44.3 0.9 1.1e-10 41.3 0.9 2.8 1 0 0 1 1 1 1 KIX domain KIX PF02172.16 PXF40327.1 - 0.13 12.5 0.9 0.53 10.6 0.1 2.5 2 0 0 2 2 2 0 KIX domain SUIM_assoc PF16619.5 PXF40328.1 - 0.016 15.3 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Plant_tran PF04827.14 PXF40329.1 - 9.2e-45 152.8 0.3 1.1e-44 152.5 0.3 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF40329.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease zf-C2H2 PF00096.26 PXF40331.1 - 1.6e-14 53.4 39.3 0.0011 19.3 1.4 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF40331.1 - 4e-14 52.1 37.8 0.0087 16.8 1.5 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF40331.1 - 3.8e-10 39.7 34.8 0.043 14.3 0.1 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-Di19 PF05605.12 PXF40331.1 - 3.5e-05 24.0 2.4 3.5e-05 24.0 2.4 4.0 1 1 4 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PXF40331.1 - 0.0002 21.3 1.5 0.0002 21.3 1.5 6.4 7 0 0 7 7 7 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF40331.1 - 0.00025 21.7 12.8 0.00034 21.3 4.7 2.8 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PXF40331.1 - 0.0018 18.5 12.6 0.11 12.8 0.2 5.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PXF40331.1 - 0.0035 17.1 1.4 0.0035 17.1 1.4 5.4 5 1 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 PXF40331.1 - 0.055 13.2 33.0 0.67 9.8 1.0 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type ADK_lid PF05191.14 PXF40331.1 - 0.059 13.4 16.6 0.66 10.0 1.4 4.2 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-met PF12874.7 PXF40331.1 - 0.16 12.4 9.9 6.9 7.2 0.3 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.7 PXF40331.1 - 0.61 10.2 24.4 0.44 10.6 1.3 4.2 3 1 0 3 3 3 0 Double zinc ribbon zf-RING_7 PF02591.15 PXF40331.1 - 0.71 10.1 10.7 33 4.8 0.3 4.6 4 0 0 4 4 4 0 C4-type zinc ribbon domain HNH_5 PF14279.6 PXF40331.1 - 4.8 7.1 16.4 2.7 7.9 0.7 3.9 3 1 1 4 4 4 0 HNH endonuclease GAGA PF09237.11 PXF40331.1 - 4.9 7.0 9.7 3.2 7.6 0.2 3.3 1 1 2 3 3 3 0 GAGA factor zf-ZPR1 PF03367.13 PXF40331.1 - 9.8 6.0 13.5 1.6 8.6 0.5 3.3 2 1 0 3 3 3 0 ZPR1 zinc-finger domain R3H PF01424.22 PXF40332.1 - 2.4e-06 27.4 0.1 5.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 R3H domain Ank_2 PF12796.7 PXF40333.1 - 3.4e-35 120.5 10.5 5e-14 52.7 1.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF40333.1 - 3.6e-20 72.1 4.6 3.4e-12 46.6 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PXF40333.1 - 7.4e-20 70.4 1.4 2.4e-06 27.8 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PXF40333.1 - 8.9e-20 68.7 1.4 0.00043 20.5 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PXF40333.1 - 2.3e-19 69.2 2.6 1.8e-09 37.7 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) CENP-B_dimeris PF09026.10 PXF40333.1 - 0.011 16.1 0.4 0.025 15.0 0.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1843 PF08898.10 PXF40333.1 - 0.092 13.3 0.8 0.25 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SNF2_N PF00176.23 PXF40334.1 - 6.5e-56 189.5 1.8 3.5e-54 183.8 0.1 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF40334.1 - 1.1e-17 64.4 0.0 2.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 PXF40334.1 - 4.1e-10 39.3 5.0 1e-09 38.1 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF40334.1 - 1e-09 38.6 5.3 3.2e-09 36.9 5.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PXF40334.1 - 6e-07 29.2 1.8 6e-07 29.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF40334.1 - 8.3e-07 28.9 3.5 2e-06 27.6 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PXF40334.1 - 5.2e-06 26.2 4.4 1.4e-05 24.9 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF40334.1 - 0.00011 21.9 8.1 0.00021 21.1 2.2 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PXF40334.1 - 0.0011 19.0 6.7 0.0032 17.4 6.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF40334.1 - 0.0048 17.2 7.9 0.033 14.5 7.9 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PXF40334.1 - 0.0082 16.3 4.5 0.019 15.1 4.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 PXF40334.1 - 0.0092 16.0 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TerY_C PF15616.6 PXF40334.1 - 0.025 14.7 3.0 0.051 13.7 2.0 2.1 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_11 PF17123.5 PXF40334.1 - 0.039 13.7 0.6 0.11 12.3 0.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_U57 PF05582.12 PXF40334.1 - 0.11 11.8 0.2 0.24 10.6 0.2 1.6 1 0 0 1 1 1 0 YabG peptidase U57 Trm112p PF03966.16 PXF40334.1 - 0.16 12.6 0.1 29 5.3 0.0 2.9 2 0 0 2 2 2 0 Trm112p-like protein zf-C2HC5 PF06221.13 PXF40334.1 - 0.37 10.8 3.6 0.19 11.8 0.8 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-Nse PF11789.8 PXF40334.1 - 0.75 9.7 6.4 0.14 12.0 2.4 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PXF40334.1 - 1.4 8.9 3.4 2.9 7.9 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 PXF40334.1 - 3.1 7.5 5.3 7.2 6.3 5.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DDE_Tnp_4 PF13359.6 PXF40335.1 - 1.6e-19 70.1 0.0 2.8e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 PXF40335.1 - 0.026 14.3 0.1 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease zf-C2HC_2 PF13913.6 PXF40338.1 - 0.0026 17.6 0.1 0.0092 15.9 0.1 2.0 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF2884 PF11101.8 PXF40338.1 - 0.038 13.5 3.8 0.046 13.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Dimer_Tnp_hAT PF05699.14 PXF40339.1 - 7.4e-17 60.9 0.0 1.7e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ammonium_transp PF00909.21 PXF40340.1 - 3.2e-121 404.8 33.3 3.8e-121 404.5 33.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HSP90 PF00183.18 PXF40343.1 - 1.9e-184 614.4 23.7 3.8e-184 613.4 23.7 1.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PXF40343.1 - 8.3e-12 45.6 0.0 2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PXF40343.1 - 6.7e-11 42.2 0.2 1.9e-10 40.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cytomega_UL20A PF05984.12 PXF40343.1 - 1.1 9.6 5.0 3.1 8.1 5.0 1.8 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Pkinase PF00069.25 PXF40344.1 - 8.2e-12 45.0 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40344.1 - 3.1e-06 26.7 0.0 4.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1120 PF06551.12 PXF40344.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) G10 PF01125.17 PXF40345.1 - 5.4e-42 143.0 0.0 8.8e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 G10 protein Med22 PF06179.12 PXF40346.1 - 1.9e-11 44.1 4.2 2.3e-11 43.8 4.2 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Syntaxin_2 PF14523.6 PXF40346.1 - 0.074 13.4 1.0 8.5 6.8 0.2 2.5 2 1 0 2 2 2 0 Syntaxin-like protein SPG48 PF14764.6 PXF40347.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking 60KD_IMP PF02096.20 PXF40348.1 - 6.5e-53 179.0 3.4 8.3e-53 178.7 3.4 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Cation_efflux PF01545.21 PXF40349.1 - 1e-28 100.4 13.1 1.4e-28 100.0 13.1 1.2 1 0 0 1 1 1 1 Cation efflux family Ribosomal_L23 PF00276.20 PXF40349.1 - 0.042 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L23 ACP PF06857.11 PXF40349.1 - 0.046 14.0 0.7 0.13 12.5 0.7 1.8 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) NAD_binding_10 PF13460.6 PXF40352.1 - 8.7e-36 123.5 0.0 9.8e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PXF40352.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PXF40352.1 - 5.4e-10 39.2 0.1 9.5e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 PXF40352.1 - 0.00027 20.1 0.1 0.00035 19.7 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PXF40352.1 - 0.00034 19.7 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 PXF40352.1 - 0.00091 19.3 0.0 0.0021 18.2 0.1 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 PXF40352.1 - 0.046 14.1 0.1 0.085 13.3 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF40352.1 - 0.05 13.7 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 PXF40352.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 PXF40352.1 - 0.091 13.2 0.3 0.16 12.4 0.3 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Abhydrolase_1 PF00561.20 PXF40353.1 - 2.1e-11 43.9 0.0 3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF40353.1 - 5.7e-05 23.8 0.1 0.00028 21.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family CHAT PF12770.7 PXF40355.1 - 2.3e-14 53.5 0.0 2.5e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 PXF40355.1 - 0.11 11.6 0.3 0.15 11.1 0.3 1.1 1 0 0 1 1 1 0 Peptidase family C50 FTA4 PF13093.6 PXF40356.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_13 PF13166.6 PXF40356.1 - 0.036 12.7 0.1 0.045 12.4 0.1 1.0 1 0 0 1 1 1 0 AAA domain CHDCT2 PF08074.11 PXF40356.1 - 0.043 14.0 0.1 0.066 13.4 0.1 1.4 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain EzrA PF06160.12 PXF40356.1 - 0.099 10.8 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Albumin_I_a PF16720.5 PXF40357.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Albumin I chain a HTH_Tnp_Tc5 PF03221.16 PXF40361.1 - 0.11 12.5 0.1 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 Tc5 transposase DNA-binding domain CCT PF06203.14 PXF40364.1 - 1.7e-18 66.4 12.7 4.8e-18 64.9 12.7 1.8 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 PXF40364.1 - 8.4e-05 22.7 4.9 0.00017 21.7 4.9 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF1560 PF07597.11 PXF40364.1 - 0.0096 15.9 0.4 0.027 14.5 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1560) CEBP_ZZ PF16366.5 PXF40364.1 - 0.024 14.9 5.8 0.047 13.9 5.8 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-SNAP50_C PF12251.8 PXF40364.1 - 0.67 9.6 4.8 1.1 8.9 4.8 1.3 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Casc1_N PF15927.5 PXF40364.1 - 5.6 6.6 16.9 9.9 5.8 16.9 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus adh_short PF00106.25 PXF40365.1 - 1.2e-25 90.2 1.0 3.6e-25 88.6 1.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF40365.1 - 1.6e-23 83.5 0.3 8.6e-13 48.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF40365.1 - 0.019 14.9 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 PXF40365.1 - 0.053 13.0 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 PXF40367.1 - 2.1e-65 220.7 0.0 3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40367.1 - 1e-30 106.9 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF40367.1 - 0.00021 20.3 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PXF40367.1 - 0.0012 18.2 0.0 0.044 13.1 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF40367.1 - 0.031 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF40367.1 - 0.035 14.0 0.4 4.2 7.2 0.2 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 PXF40368.1 - 4.8e-40 134.8 26.0 1.6e-08 35.1 0.5 10.4 10 0 0 10 10 10 8 WD domain, G-beta repeat Utp13 PF08625.11 PXF40368.1 - 1.3e-18 67.2 0.0 3e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 PXF40368.1 - 2.1e-13 50.4 1.3 0.0073 16.6 0.1 6.2 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PXF40368.1 - 2.8e-10 39.5 10.7 0.0003 19.6 0.5 5.6 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PXF40368.1 - 8.2e-09 34.9 3.1 0.048 12.6 0.0 5.1 4 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PXF40368.1 - 0.011 16.2 0.9 9 6.9 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain SGL PF08450.12 PXF40368.1 - 0.019 14.5 0.2 2 7.9 0.0 3.3 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region CCDC53 PF10152.9 PXF40368.1 - 0.073 13.5 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pkinase PF00069.25 PXF40374.1 - 4.7e-26 91.7 0.0 7.5e-26 91.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40374.1 - 1.6e-13 50.6 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF40374.1 - 2.3e-07 31.0 0.0 0.00027 20.9 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF40374.1 - 0.00041 19.2 0.0 0.00055 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF40374.1 - 0.012 14.9 0.0 0.033 13.5 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF40374.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 PXF40375.1 - 2.6e-25 89.3 0.0 3.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40375.1 - 6.8e-13 48.5 0.0 8.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF40375.1 - 4.7e-06 26.7 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF40375.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PXF40375.1 - 0.016 14.0 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PXF40375.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phytoreo_P8 PF07124.11 PXF40376.1 - 0.035 13.1 1.0 0.57 9.1 0.9 2.0 1 1 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Methyltransf_21 PF05050.12 PXF40377.1 - 6.2e-13 49.1 0.0 9.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Hint PF01079.20 PXF40379.1 - 3e-15 56.3 0.1 4.8e-15 55.7 0.1 1.3 1 1 0 1 1 1 1 Hint module Intein_splicing PF14890.6 PXF40379.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Intein splicing domain DUF1218 PF06749.12 PXF40381.1 - 0.018 15.5 3.4 0.11 13.1 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DUF4083 PF13314.6 PXF40381.1 - 0.052 13.5 0.6 0.18 11.8 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Sensor PF13796.6 PXF40381.1 - 0.16 12.0 2.1 15 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative sensor DDDD PF10161.9 PXF40381.1 - 0.84 9.4 2.6 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein UbiA PF01040.18 PXF40381.1 - 1.3 8.3 9.6 4.5 6.5 0.7 3.1 3 0 0 3 3 3 0 UbiA prenyltransferase family MFS_1 PF07690.16 PXF40382.1 - 4.1e-31 108.2 44.3 3e-21 75.7 31.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PXF40382.1 - 8e-30 104.1 22.7 5.9e-27 94.6 9.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 PXF40383.1 - 0.002 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40383.1 - 0.0054 16.0 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF40383.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CBS PF00571.28 PXF40385.1 - 3.2e-21 75.5 1.4 1.7e-09 38.0 0.1 2.9 2 0 0 2 2 2 2 CBS domain DHH PF01368.20 PXF40385.1 - 2e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 PXF40385.1 - 0.0003 21.2 0.3 0.00077 19.9 0.2 1.7 2 0 0 2 2 2 1 DHHA1 domain PPR PF01535.20 PXF40385.1 - 0.00031 20.8 0.0 3.4 8.1 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 PXF40385.1 - 0.0058 16.0 0.0 0.017 14.5 0.0 1.8 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RecA_dep_nuc PF16786.5 PXF40385.1 - 0.057 13.6 0.1 0.21 11.7 0.1 2.0 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease PAP2 PF01569.21 PXF40387.1 - 1.1e-12 47.9 5.0 1.1e-12 47.9 5.0 2.8 1 1 1 2 2 2 1 PAP2 superfamily Pilin_N PF07790.11 PXF40389.1 - 0.19 12.7 0.1 0.23 12.4 0.1 1.1 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Malectin PF11721.8 PXF40390.1 - 1.5e-05 25.2 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Malectin domain DUF3344 PF11824.8 PXF40390.1 - 0.032 13.8 0.1 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3344) AAA PF00004.29 PXF40392.1 - 3.8e-08 33.8 0.0 8.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PXF40392.1 - 0.0036 16.8 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 PXF40392.1 - 0.0098 15.7 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PXF40392.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 PXF40392.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 PXF40392.1 - 0.039 14.2 0.1 0.2 11.9 0.1 2.2 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 PXF40392.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA PF00004.29 PXF40393.1 - 0.018 15.5 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ferrochelatase PF00762.19 PXF40395.1 - 3.4e-91 305.6 0.0 3.9e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 PXF40395.1 - 1.6e-06 28.4 0.1 0.0045 17.3 0.0 2.9 3 0 0 3 3 3 2 CbiX Sugar-bind PF04198.13 PXF40395.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Peptidase_M20 PF01546.28 PXF40396.1 - 1.7e-30 106.3 0.0 2.5e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF40396.1 - 1.9e-13 50.3 0.0 3.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain SAYSvFN PF10260.9 PXF40397.1 - 3.8e-20 71.6 0.2 5.3e-20 71.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) RGS-like PF09128.11 PXF40397.1 - 0.008 15.9 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain FSH1 PF03959.13 PXF40398.1 - 1e-33 116.8 0.0 3.3e-33 115.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 PXF40398.1 - 0.041 13.2 0.0 0.094 12.0 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 EcKinase PF02958.20 PXF40399.1 - 5.7e-14 52.1 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 PXF40399.1 - 1.9e-08 34.5 0.0 4.3e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 PXF40399.1 - 9.1e-05 21.5 0.0 0.00028 19.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) VCBS PF13517.6 PXF40400.1 - 7.4e-25 87.3 35.9 1.2e-10 41.8 3.5 5.8 2 2 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 PXF40400.1 - 9.5e-07 28.7 0.0 2.4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 PXF40400.1 - 0.0025 17.9 24.6 0.065 13.4 0.3 4.8 5 0 0 5 5 5 3 FG-GAP repeat CBM_20 PF00686.19 PXF40401.1 - 1.2e-19 69.9 0.5 2.1e-19 69.2 0.5 1.4 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 PXF40401.1 - 7.8e-15 55.3 0.0 3.1e-10 40.2 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PXF40401.1 - 1.2e-08 35.3 0.1 6.7e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Tail_tube PF10618.9 PXF40401.1 - 0.069 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein Methyltransf_5 PF01795.19 PXF40402.1 - 1.6e-92 310.3 0.1 2.4e-92 309.7 0.1 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 PXF40402.1 - 0.00025 21.7 0.1 0.0007 20.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40402.1 - 0.023 15.3 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 PXF40402.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 PXF40402.1 - 0.18 12.6 0.0 0.57 11.0 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 PXF40406.1 - 1.3e-15 57.6 0.0 2.8e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF40406.1 - 3.4e-11 42.7 0.0 5.8e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF40406.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PXF40406.1 - 1e-06 28.1 0.0 5.4e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 PXF40406.1 - 2.4e-05 23.9 0.0 0.00013 21.5 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 PXF40406.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 PXF40406.1 - 0.00029 20.5 0.0 0.00076 19.1 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 PXF40406.1 - 0.035 13.2 0.1 0.12 11.5 0.1 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FLgD_tudor PF13861.6 PXF40406.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 FlgD Tudor-like domain Alk_phosphatase PF00245.20 PXF40407.1 - 9e-78 262.1 3.7 1.7e-69 234.8 3.8 2.0 2 0 0 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.18 PXF40407.1 - 0.0016 17.8 0.3 0.0054 16.1 0.1 1.8 2 1 0 2 2 2 1 Metalloenzyme superfamily HD PF01966.22 PXF40409.1 - 8.9e-10 38.8 0.1 1.9e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 HD domain Ku PF02735.16 PXF40409.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Pkinase PF00069.25 PXF40410.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40410.1 - 0.00041 19.7 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Herpes_ICP4_N PF03584.15 PXF40410.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region HAUS5 PF14817.6 PXF40410.1 - 0.033 12.9 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 HSBP1 PF06825.12 PXF40411.1 - 6.4e-10 38.7 3.1 8.5e-10 38.3 3.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Fzo_mitofusin PF04799.13 PXF40411.1 - 0.00084 18.9 0.4 0.00096 18.7 0.4 1.1 1 0 0 1 1 1 1 fzo-like conserved region BLOC1_2 PF10046.9 PXF40411.1 - 0.0065 16.7 0.3 0.0092 16.3 0.3 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 phiKZ_IP PF12699.7 PXF40411.1 - 0.0085 15.3 0.2 0.0088 15.2 0.2 1.0 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins DUF3091 PF11291.8 PXF40411.1 - 0.0091 16.1 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3091) V-ATPase_G PF03179.15 PXF40411.1 - 0.01 16.3 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Noelin-1 PF12308.8 PXF40411.1 - 0.011 15.8 0.2 0.012 15.5 0.2 1.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein Lectin_N PF03954.14 PXF40411.1 - 0.018 14.8 1.3 0.025 14.3 1.3 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 PXF40411.1 - 0.018 15.1 0.4 0.023 14.8 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 PXF40411.1 - 0.018 15.3 0.3 0.023 15.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 PXF40411.1 - 0.019 15.0 0.3 0.022 14.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 PXF40411.1 - 0.027 15.0 0.7 0.067 13.8 0.6 1.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nas2_N PF18265.1 PXF40411.1 - 0.032 14.1 1.8 0.33 10.9 0.1 2.1 1 1 1 2 2 2 0 Nas2 N_terminal domain CDC73_N PF16050.5 PXF40411.1 - 0.033 13.5 0.1 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal Flagellar_put PF12611.8 PXF40411.1 - 0.044 13.6 0.3 0.094 12.5 0.3 1.5 1 0 0 1 1 1 0 Putative flagellar HAUS6_N PF14661.6 PXF40411.1 - 0.059 12.9 0.3 0.068 12.7 0.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sipho_Gp157 PF05565.11 PXF40411.1 - 0.062 13.3 0.2 0.076 13.0 0.2 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Put_Phosphatase PF06888.12 PXF40411.1 - 0.066 12.6 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 Putative Phosphatase DUF4208 PF13907.6 PXF40411.1 - 0.066 13.6 0.1 0.09 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) LPP20 PF02169.16 PXF40411.1 - 0.071 13.5 0.7 0.087 13.2 0.7 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Shugoshin_N PF07558.11 PXF40411.1 - 0.096 12.6 1.1 6.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.11 PXF40411.1 - 0.11 12.9 2.8 0.53 10.7 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 PXF40411.1 - 0.13 12.3 2.1 0.32 11.0 2.1 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.9 PXF40411.1 - 0.14 12.1 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O ABC_tran_CTD PF16326.5 PXF40411.1 - 0.17 12.2 1.2 1.2 9.5 1.3 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain CHD5 PF04420.14 PXF40411.1 - 0.18 11.7 1.0 0.26 11.2 1.0 1.2 1 1 0 1 1 1 0 CHD5-like protein Hint PF01079.20 PXF40412.1 - 6.6e-14 51.9 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Hint module Pentapeptide_3 PF13576.6 PXF40412.1 - 1e-07 31.9 27.1 0.0051 16.9 4.3 5.5 4 2 0 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 PXF40412.1 - 3.3e-05 24.0 16.7 0.034 14.3 1.5 4.2 2 2 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 PXF40412.1 - 0.0012 18.5 1.8 2 8.1 0.1 4.5 3 1 1 4 4 4 2 Pentapeptide repeats (8 copies) An_peroxidase PF03098.15 PXF40414.1 - 4.1e-116 388.7 0.0 1.3e-96 324.3 0.0 2.0 2 0 0 2 2 2 2 Animal haem peroxidase An_peroxidase PF03098.15 PXF40415.1 - 5.7e-135 450.9 0.0 6.6e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase PseudoU_synth_2 PF00849.22 PXF40416.1 - 2e-29 102.7 0.0 2.6e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase PMT PF02366.18 PXF40417.1 - 5.4e-31 108.0 14.9 5.4e-31 108.0 14.9 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PXF40417.1 - 2.6e-29 102.3 19.2 2.6e-29 102.3 19.2 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 PXF40417.1 - 3.2e-06 27.4 12.0 3.2e-06 27.4 12.0 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DNA_topoisoIV PF00521.20 PXF40418.1 - 3.2e-148 494.2 0.0 3.9e-148 493.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 PXF40418.1 - 5.7e-56 185.8 14.1 6.2e-11 41.6 0.0 7.4 6 1 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller PurA PF04845.13 PXF40418.1 - 0.021 14.2 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 PurA ssDNA and RNA-binding protein DUF4890 PF16231.5 PXF40418.1 - 0.09 13.3 0.4 0.19 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) EXOSC1 PF10447.9 PXF40419.1 - 0.041 14.5 0.3 3.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 AdoHcyase_NAD PF00670.21 PXF40422.1 - 1.1e-41 142.6 0.2 1.3e-41 142.4 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF40422.1 - 6.7e-05 22.3 0.2 8.5e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF40422.1 - 0.012 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF5402 PF17393.2 PXF40422.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5402) Transposase_21 PF02992.14 PXF40425.1 - 2.5e-07 30.2 0.1 4e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 PXF40425.1 - 6.3e-05 22.4 0.0 0.00035 19.9 0.0 2.0 1 1 0 1 1 1 1 Plavaka transposase DUF1258 PF06869.12 PXF40425.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) GRIP PF01465.20 PXF40425.1 - 0.039 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 GRIP domain Peptidase_C47 PF05543.13 PXF40426.1 - 0.0056 16.3 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Staphopain peptidase C47 YABBY PF04690.13 PXF40428.1 - 0.073 13.6 0.3 0.1 13.2 0.3 1.1 1 0 0 1 1 1 0 YABBY protein WD40 PF00400.32 PXF40429.1 - 7.1e-64 210.2 22.2 2.7e-08 34.3 0.2 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat NB-ARC PF00931.22 PXF40429.1 - 5.1e-13 48.8 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF40429.1 - 6.9e-13 48.7 10.5 0.22 11.8 0.1 8.2 1 1 8 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain ChapFlgA PF13144.6 PXF40429.1 - 1.3e-08 34.9 5.5 2.9 8.0 0.1 6.4 4 2 2 6 6 6 3 Chaperone for flagella basal body P-ring formation DUF727 PF05303.12 PXF40429.1 - 2.4e-05 24.3 0.9 1e+02 3.0 0.0 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF727) PD40 PF07676.12 PXF40429.1 - 0.00065 19.6 0.0 92 3.1 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BRK PF07533.16 PXF40429.1 - 0.00091 18.8 0.0 2.1e+02 1.7 0.0 6.2 6 0 0 6 6 6 0 BRK domain AAA_22 PF13401.6 PXF40429.1 - 0.0079 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Jnk-SapK_ap_N PF09744.9 PXF40429.1 - 0.0085 16.3 0.8 0.021 15.1 0.8 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF2314 PF10077.9 PXF40429.1 - 0.011 15.9 0.0 6 7.0 0.0 3.3 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2314) DUF3313 PF11769.8 PXF40429.1 - 0.051 13.4 0.2 11 5.8 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) APAF1_C PF17908.1 PXF40429.1 - 0.063 13.3 0.3 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 APAF-1 helical domain IKI3 PF04762.12 PXF40429.1 - 0.08 10.9 0.0 0.14 10.2 0.0 1.3 1 0 0 1 1 1 0 IKI3 family MG1 PF17790.1 PXF40429.1 - 0.083 13.3 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Macroglobulin domain MG1 WD40_like PF17005.5 PXF40429.1 - 0.18 11.1 0.0 76 2.5 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain AIG1 PF04548.16 PXF40430.1 - 2.9e-11 43.1 0.0 1e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PXF40430.1 - 3.9e-08 33.4 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF40430.1 - 0.0016 18.5 0.3 0.028 14.5 0.0 2.8 3 0 0 3 3 3 1 Dynamin family DUF615 PF04751.14 PXF40430.1 - 0.015 15.3 1.1 0.031 14.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Ank_2 PF12796.7 PXF40431.1 - 1e-17 64.5 3.0 9.1e-10 39.0 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PXF40431.1 - 2.2e-13 49.0 6.2 0.0015 18.8 0.1 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 PXF40431.1 - 1.5e-11 44.6 2.4 0.00036 21.1 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PXF40431.1 - 1.2e-10 41.4 7.1 8.5e-05 22.8 0.3 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PXF40431.1 - 1.8e-10 40.8 17.0 0.0019 18.5 0.2 6.0 5 1 1 6 6 6 3 Ankyrin repeat tRNA_int_endo PF01974.17 PXF40432.1 - 5.1e-14 52.1 0.0 7.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PhoLip_ATPase_C PF16212.5 PXF40433.1 - 5.1e-53 180.4 19.6 5.1e-53 180.4 19.6 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PXF40433.1 - 4e-15 55.3 3.6 1e-14 53.9 3.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PXF40433.1 - 2.1e-14 54.3 3.9 1.3e-07 32.1 0.7 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PXF40433.1 - 2.5e-13 50.0 0.0 1.4e-12 47.5 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PXF40433.1 - 1.6e-12 47.3 0.0 6.7e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PXF40433.1 - 0.00075 19.3 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAP_fibrillin PF04755.12 PXF40435.1 - 3e-15 56.7 0.0 1.6e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 PAP_fibrillin DAHP_synth_2 PF01474.16 PXF40436.1 - 7.6e-120 400.4 0.0 1.1e-119 399.8 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family SLT_L PF14718.6 PXF40436.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain Uma2 PF05685.12 PXF40437.1 - 2.3e-10 40.3 0.1 1.1e-09 38.0 0.1 1.9 1 1 0 1 1 1 1 Putative restriction endonuclease Lsr2 PF11774.8 PXF40437.1 - 0.41 10.8 8.2 0.15 12.2 5.3 1.8 2 0 0 2 2 2 0 Lsr2 DAHP_synth_2 PF01474.16 PXF40438.1 - 1.3e-169 564.4 0.0 1.4e-169 564.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Uma2 PF05685.12 PXF40439.1 - 2.8e-10 40.0 0.1 1.3e-09 37.8 0.1 1.9 1 1 0 1 1 1 1 Putative restriction endonuclease DAHP_synth_2 PF01474.16 PXF40440.1 - 1.3e-169 564.4 0.0 1.4e-169 564.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Mlo PF03094.15 PXF40443.1 - 4e-07 28.8 17.2 0.0011 17.4 0.9 3.2 3 0 0 3 3 3 3 Mlo family GMC_oxred_N PF00732.19 PXF40444.1 - 7.4e-37 127.3 0.0 1.5e-36 126.3 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF40444.1 - 8.8e-12 45.8 0.0 1.6e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Phage_int_SAM_1 PF02899.17 PXF40450.1 - 0.035 14.4 0.4 0.25 11.6 0.0 2.5 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 PXF40450.1 - 0.067 13.7 3.9 0.61 10.6 0.1 3.3 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain Peptidase_M61_N PF17899.1 PXF40450.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain Mak10 PF04112.13 PXF40451.1 - 1.2e-25 89.9 3.0 7.4e-24 84.1 0.1 2.7 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TERT_thumb PF17984.1 PXF40451.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain WD40 PF00400.32 PXF40452.1 - 5.9e-45 150.4 24.6 4.5e-09 36.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40452.1 - 2.1e-21 76.0 6.1 9.3e-06 25.9 0.4 6.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF40452.1 - 0.00075 18.9 0.0 0.11 11.8 0.0 2.4 2 1 1 3 3 3 2 WD40-like domain VID27 PF08553.10 PXF40452.1 - 0.026 13.6 0.0 0.65 9.0 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain IKI3 PF04762.12 PXF40452.1 - 0.29 9.1 3.5 0.4 8.6 0.3 2.4 2 1 1 3 3 3 0 IKI3 family Chromo PF00385.24 PXF40453.1 - 5.6e-10 39.0 0.2 9e-10 38.3 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TFIIB PF00382.19 PXF40454.1 - 7.6e-16 57.9 1.1 4.9e-14 52.1 0.1 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_N PF00134.23 PXF40454.1 - 5.5e-06 26.2 0.1 0.037 13.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Zn_Tnp_IS1595 PF12760.7 PXF40454.1 - 0.0015 18.5 2.1 0.0029 17.6 2.1 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain HTH_23 PF13384.6 PXF40454.1 - 0.1 12.5 0.2 0.73 9.7 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Mga PF08280.11 PXF40454.1 - 0.22 11.6 0.2 0.61 10.2 0.2 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TF_Zn_Ribbon PF08271.12 PXF40454.1 - 0.24 10.9 1.0 0.55 9.8 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RPA_interact_C PF14768.6 PXF40454.1 - 0.66 10.6 3.6 0.89 10.2 1.3 2.3 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Zn_ribbon_SprT PF17283.2 PXF40454.1 - 2 8.4 5.6 4 7.4 5.6 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain HTH_Crp_2 PF13545.6 PXF40454.1 - 2.2 8.3 3.8 60 3.7 0.0 3.7 4 0 0 4 4 4 0 Crp-like helix-turn-helix domain DAO PF01266.24 PXF40455.1 - 4.5e-53 181.1 0.3 5.1e-53 180.9 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF40455.1 - 5.7e-06 26.4 1.7 0.0015 18.5 0.1 3.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PXF40455.1 - 0.00016 21.8 0.0 0.00042 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PXF40455.1 - 0.0014 18.0 0.0 0.088 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PXF40455.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 PXF40455.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prenylcys_lyase PF07156.14 PXF40455.1 - 0.024 13.7 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase Amino_oxidase PF01593.24 PXF40455.1 - 0.033 13.5 0.1 0.042 13.1 0.1 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 PXF40455.1 - 0.039 13.1 0.1 6.3 5.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 PXF40455.1 - 0.049 14.2 0.4 0.79 10.3 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 PXF40455.1 - 0.17 12.5 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L6 PF00347.23 PXF40456.1 - 9.3e-10 39.1 0.0 2.8e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L6 Ribosomal_S18 PF01084.20 PXF40457.1 - 1.2e-17 63.9 0.1 2.1e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Osmo_CC PF08946.10 PXF40457.1 - 0.097 12.9 0.3 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil NnrU PF07298.11 PXF40458.1 - 3.4e-50 170.5 8.1 3.4e-50 170.5 8.1 1.5 2 0 0 2 2 2 1 NnrU protein PEMT PF04191.13 PXF40458.1 - 0.0046 17.3 1.2 0.015 15.7 0.1 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase TRAPP PF04051.16 PXF40459.1 - 4.5e-39 133.5 0.0 5.8e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Asp_protease PF09668.10 PXF40460.1 - 1.4e-49 167.0 0.7 1.4e-49 167.0 0.7 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 PXF40460.1 - 5.4e-18 65.4 0.1 1.2e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 PXF40460.1 - 1.9e-10 40.4 0.2 5.7e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Asp_protease_2 PF13650.6 PXF40460.1 - 3.9e-09 37.0 0.1 1.2e-08 35.4 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.8 PXF40460.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PXF40460.1 - 2.1e-06 27.4 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 PXF40460.1 - 0.00016 21.4 0.1 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 PXF40460.1 - 0.00021 21.5 0.1 0.00063 20.0 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease TUG-UBL1 PF11470.8 PXF40460.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain Lant_dehydr_N PF04738.13 PXF40460.1 - 0.052 11.6 0.4 0.08 11.0 0.4 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus HOIP-UBA PF16678.5 PXF40460.1 - 0.056 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Bep_C_terminal PF17841.1 PXF40460.1 - 0.15 12.3 0.3 6.1 7.1 0.2 2.4 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) CUE PF02845.16 PXF40460.1 - 0.16 11.7 0.1 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 CUE domain Serpin PF00079.20 PXF40461.1 - 9.1e-62 209.5 0.0 3.1e-61 207.7 0.0 1.8 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) LRR_4 PF12799.7 PXF40462.1 - 0.19 12.2 1.9 12 6.5 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 PXF40463.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_C_3 PF14497.6 PXF40464.1 - 2e-12 47.2 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PXF40464.1 - 0.00022 21.5 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PXF40464.1 - 0.0034 17.7 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF40464.1 - 0.0053 16.7 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PXF40464.1 - 0.0097 16.1 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PXF40464.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PXF40464.1 - 0.027 15.2 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 PXF40465.1 - 6.4e-16 58.4 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PXF40465.1 - 4.7e-11 42.9 0.0 1.6e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PXF40465.1 - 8.6e-06 25.9 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PXF40465.1 - 0.0002 21.7 0.1 0.00049 20.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF40465.1 - 0.005 16.8 0.0 0.022 14.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PXF40465.1 - 0.0095 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PXF40465.1 - 0.014 16.0 0.0 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF40466.1 - 3.4e-15 56.0 0.0 5.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PXF40466.1 - 1.2e-06 28.7 0.0 3.8e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF40466.1 - 4.4e-05 23.4 0.0 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PXF40466.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PXF40466.1 - 0.00023 21.3 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PXF40466.1 - 0.00045 20.8 0.0 0.0006 20.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PXF40466.1 - 0.0048 17.2 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Peptidase_C78 PF07910.13 PXF40467.1 - 7.2e-39 133.5 0.0 9.1e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Zn-C2H2_12 PF18112.1 PXF40467.1 - 0.0014 19.0 0.1 0.0041 17.6 0.1 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 PXF40467.1 - 0.0021 18.7 0.1 0.0094 16.7 0.1 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 PXF40467.1 - 0.0077 16.1 1.0 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-binding zinc-finger Gal4_dimer PF03902.13 PXF40467.1 - 0.11 12.7 0.4 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain Med14 PF08638.11 PXF40468.1 - 6.7e-13 48.5 0.1 1.3e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 GF_recep_IV PF14843.6 PXF40468.1 - 1.5 8.6 4.0 0.78 9.5 0.3 2.2 2 0 0 2 2 2 0 Growth factor receptor domain IV BtpA PF03437.15 PXF40469.1 - 0.0066 15.9 0.0 0.0094 15.4 0.0 1.1 1 0 0 1 1 1 1 BtpA family HHH_9 PF17674.1 PXF40470.1 - 0.022 15.6 0.2 0.058 14.3 0.2 1.7 1 0 0 1 1 1 0 HHH domain AAA_assoc PF14363.6 PXF40470.1 - 0.063 13.6 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA I_LWEQ PF01608.17 PXF40471.1 - 0.054 13.7 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 I/LWEQ domain XPG_I_2 PF12813.7 PXF40471.1 - 0.069 12.6 1.2 0.11 11.9 0.4 1.6 1 1 0 2 2 2 0 XPG domain containing DER1 PF04511.15 PXF40472.1 - 5.2e-58 196.1 13.1 5.9e-58 196.0 13.1 1.0 1 0 0 1 1 1 1 Der1-like family PDR_CDR PF06422.12 PXF40472.1 - 3.6 7.5 5.1 8.7 6.3 4.4 1.9 1 1 0 1 1 1 0 CDR ABC transporter ZapB PF06005.12 PXF40474.1 - 9e-05 22.8 4.5 0.0001 22.7 4.5 1.1 1 0 0 1 1 1 1 Cell division protein ZapB Tropomyosin_1 PF12718.7 PXF40474.1 - 0.00023 21.4 0.9 0.00023 21.4 0.9 1.1 1 0 0 1 1 1 1 Tropomyosin like APG6_N PF17675.1 PXF40474.1 - 0.00024 21.6 2.8 0.00027 21.5 2.8 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 PXF40474.1 - 0.0007 19.0 1.4 0.00077 18.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 PXF40474.1 - 0.0014 18.6 1.3 0.0015 18.5 1.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ATG16 PF08614.11 PXF40474.1 - 0.0021 18.3 5.3 0.0025 18.1 5.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RINT1_TIP1 PF04437.13 PXF40474.1 - 0.0036 16.3 0.3 0.0043 16.0 0.3 1.0 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Uso1_p115_C PF04871.13 PXF40474.1 - 0.0038 17.6 3.1 0.0043 17.4 3.1 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 PXF40474.1 - 0.0043 16.0 3.3 0.0048 15.8 3.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.12 PXF40474.1 - 0.007 16.4 3.2 0.0081 16.2 3.2 1.1 1 0 0 1 1 1 1 Laminin Domain II CAGE1 PF15066.6 PXF40474.1 - 0.0081 14.9 1.4 0.0086 14.8 1.4 1.1 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family Atg14 PF10186.9 PXF40474.1 - 0.0084 15.2 0.9 0.0085 15.2 0.9 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 PXF40474.1 - 0.011 15.5 1.1 0.013 15.3 1.1 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 PXF40474.1 - 0.014 15.9 2.0 0.072 13.6 2.0 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 PXF40474.1 - 0.016 15.8 2.8 0.02 15.5 2.8 1.3 1 0 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 PXF40474.1 - 0.018 15.0 6.3 0.024 14.6 6.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 PXF40474.1 - 0.023 14.9 1.6 0.027 14.7 1.6 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Syntaxin_2 PF14523.6 PXF40474.1 - 0.025 14.9 1.0 0.035 14.5 1.0 1.3 1 0 0 1 1 1 0 Syntaxin-like protein YabA PF06156.13 PXF40474.1 - 0.025 15.2 0.9 0.028 15.0 0.9 1.2 1 0 0 1 1 1 0 Initiation control protein YabA LXG PF04740.12 PXF40474.1 - 0.027 14.2 0.2 0.032 14.0 0.2 1.0 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4142 PF13628.6 PXF40474.1 - 0.03 14.5 0.1 0.035 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Snapin_Pallidin PF14712.6 PXF40474.1 - 0.032 14.6 3.8 0.043 14.2 3.8 1.2 1 0 0 1 1 1 0 Snapin/Pallidin ERM PF00769.19 PXF40474.1 - 0.038 13.8 5.3 0.045 13.6 5.3 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family COG2 PF06148.11 PXF40474.1 - 0.04 14.0 1.7 0.049 13.7 1.7 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GIT_CC PF16559.5 PXF40474.1 - 0.052 13.4 2.4 0.072 13.0 2.4 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor HDV_ag PF01517.18 PXF40474.1 - 0.069 12.9 0.2 0.083 12.7 0.2 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen DUF3053 PF11254.8 PXF40474.1 - 0.076 12.6 0.9 0.083 12.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF1664 PF07889.12 PXF40474.1 - 0.094 12.8 0.8 0.13 12.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 PXF40474.1 - 0.14 10.7 1.1 0.15 10.6 1.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1640 PF07798.11 PXF40474.1 - 0.14 12.2 5.6 0.17 11.9 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DivIC PF04977.15 PXF40474.1 - 0.18 11.6 7.1 0.39 10.5 6.0 1.9 1 1 1 2 2 2 0 Septum formation initiator XhlA PF10779.9 PXF40474.1 - 0.32 11.2 2.5 0.54 10.5 2.5 1.5 1 1 0 1 1 1 0 Haemolysin XhlA FlaC_arch PF05377.11 PXF40474.1 - 0.34 11.3 3.3 0.51 10.8 0.8 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 PXF40474.1 - 0.75 9.9 5.9 2.3 8.4 4.3 2.0 1 1 1 2 2 2 0 Swi5 DUF5595 PF18077.1 PXF40474.1 - 2.2 8.4 6.5 0.58 10.3 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) WD40_alt PF14077.6 PXF40474.1 - 3 7.8 7.4 12 5.9 2.7 2.5 1 1 1 2 2 2 0 Alternative WD40 repeat motif DUF563 PF04577.14 PXF40475.1 - 2.4e-19 70.3 0.0 6.6e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Amino_oxidase PF01593.24 PXF40476.1 - 1.2e-18 67.6 0.0 1e-14 54.7 0.0 2.6 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF40476.1 - 7.5e-14 51.7 0.3 1.7e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF40476.1 - 4.7e-07 29.7 4.3 0.0013 18.4 3.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF40476.1 - 2.1e-05 23.9 0.1 0.00026 20.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF40476.1 - 7.1e-05 21.7 1.2 0.0058 15.4 1.3 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 PXF40476.1 - 9.5e-05 21.6 1.3 0.00015 21.0 1.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 PXF40476.1 - 0.00045 19.5 0.1 0.00078 18.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 PXF40476.1 - 0.0016 18.5 3.6 1.4 8.9 0.1 3.4 4 0 0 4 4 3 2 FAD-NAD(P)-binding 3HCDH_N PF02737.18 PXF40476.1 - 0.0022 17.9 0.7 0.0046 16.9 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 PXF40476.1 - 0.0035 16.5 3.9 0.0063 15.6 3.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PXF40476.1 - 0.0037 16.7 0.7 0.0061 16.0 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PXF40476.1 - 0.0044 16.3 0.4 0.0082 15.5 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PXF40476.1 - 0.0054 16.0 0.4 0.0093 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 PXF40476.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 PXF40476.1 - 0.047 13.3 3.5 2 8.0 1.2 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 PXF40476.1 - 0.42 11.2 3.5 8.7 7.0 0.8 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Chorismate_bind PF00425.18 PXF40477.1 - 8.3e-85 284.4 0.0 1.2e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 PXF40477.1 - 1.2e-30 106.6 0.0 1.5e-28 99.8 0.0 2.3 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region Y_phosphatase PF00102.27 PXF40478.1 - 3e-55 187.3 0.0 2.1e-54 184.6 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Aconitase_B_N PF11791.8 PXF40478.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Aconitate B N-terminal domain Y_phosphatase3 PF13350.6 PXF40478.1 - 0.06 13.3 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 PXF40478.1 - 0.077 12.8 0.4 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PXF40478.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Abhydrolase_1 PF00561.20 PXF40479.1 - 4.7e-08 33.0 0.0 1.8e-06 27.8 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF40479.1 - 4.9e-06 26.0 0.0 1.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 PXF40479.1 - 0.004 15.9 0.2 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 PhoPQ-activated pathogenicity-related protein Ser_hydrolase PF06821.13 PXF40479.1 - 0.0084 16.0 0.4 2.3 8.0 0.0 2.7 3 0 0 3 3 3 2 Serine hydrolase NB-ARC PF00931.22 PXF40480.1 - 3.4e-11 42.8 0.0 6.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain WD40 PF00400.32 PXF40480.1 - 3.3e-07 30.9 3.8 9.4e-05 23.1 0.2 5.2 4 0 0 4 4 4 1 WD domain, G-beta repeat NACHT PF05729.12 PXF40480.1 - 8.7e-05 22.5 0.0 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 PXF40480.1 - 0.00035 21.0 6.4 0.0022 18.4 0.9 3.8 3 1 1 4 4 4 1 AAA ATPase domain PQQ_2 PF13360.6 PXF40480.1 - 0.00063 19.4 0.1 0.3 10.6 0.0 2.7 2 1 0 2 2 2 2 PQQ-like domain AAA_25 PF13481.6 PXF40480.1 - 0.0034 17.0 0.1 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain PQQ_3 PF13570.6 PXF40480.1 - 0.022 15.2 1.9 6.4 7.4 0.2 4.3 5 0 0 5 5 4 0 PQQ-like domain APAF1_C PF17908.1 PXF40480.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 APAF-1 helical domain VID27 PF08553.10 PXF40480.1 - 0.05 12.7 0.0 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain AAA_5 PF07728.14 PXF40480.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Me-amine-dh_L PF02975.14 PXF40480.1 - 0.063 13.8 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain RNA_helicase PF00910.22 PXF40480.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 PXF40480.1 - 0.13 12.4 0.0 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain FKBP_C PF00254.28 PXF40482.1 - 3.8e-18 65.6 0.0 5.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TAT_signal PF10518.9 PXF40482.1 - 0.0018 18.0 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence ADK PF00406.22 PXF40484.1 - 3.9e-48 163.4 0.0 6.1e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PXF40484.1 - 1.3e-26 93.6 0.0 2.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3054 PF11255.8 PXF40484.1 - 8.9e-22 77.7 5.1 1.8e-21 76.7 5.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) Hydin_ADK PF17213.3 PXF40484.1 - 5.2e-06 26.9 1.5 0.029 14.6 0.0 2.7 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 PXF40484.1 - 7e-06 26.6 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PXF40484.1 - 0.002 18.3 0.4 0.035 14.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 PXF40484.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 PXF40484.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase VRR_NUC PF08774.11 PXF40485.1 - 3.8e-16 59.1 0.0 1.5e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 VRR-NUC domain DUF3622 PF12286.8 PXF40485.1 - 0.082 13.3 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) DNA_topoisoIV PF00521.20 PXF40486.1 - 2.8e-117 392.2 0.0 4.1e-117 391.7 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PXF40486.1 - 3.4e-46 156.7 3.2 9.8e-46 155.2 3.2 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PXF40486.1 - 1.3e-25 89.9 0.2 3e-25 88.7 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 PXF40486.1 - 5.6e-15 55.8 0.0 2.9e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PXF40486.1 - 1.1e-08 35.2 0.0 3.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Redoxin PF08534.10 PXF40486.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Redoxin eIF-5a PF01287.20 PXF40487.1 - 6e-23 80.7 0.8 8.2e-23 80.3 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 PXF40487.1 - 0.0047 16.9 0.1 0.0071 16.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain CAF20 PF17052.5 PXF40487.1 - 0.076 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Cap associated factor DUF1248 PF06852.12 PXF40487.1 - 0.094 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) DUF2505 PF10698.9 PXF40490.1 - 4e-08 33.5 0.0 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2505) DUF4333 PF14230.6 PXF40490.1 - 0.1 12.9 0.7 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) AAA_lid_9 PF17871.1 PXF40491.1 - 2.7e-15 56.1 0.6 5.6e-15 55.1 0.6 1.5 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 PXF40491.1 - 1.1e-06 29.0 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF40491.1 - 0.0011 19.3 0.5 0.037 14.4 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain Cyclin_N PF00134.23 PXF40491.1 - 0.0071 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_5 PF07728.14 PXF40491.1 - 0.013 15.5 0.2 0.044 13.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PXF40491.1 - 0.057 13.3 0.1 0.27 11.1 0.1 2.1 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.13 PXF40491.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 PXF40491.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SWIB PF02201.18 PXF40492.1 - 1.3e-10 41.0 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Proteasome PF00227.26 PXF40493.1 - 6.2e-60 201.9 0.0 8.2e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF40493.1 - 3e-14 52.4 0.1 5.5e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ubiquitin PF00240.23 PXF40494.1 - 6.2e-05 22.7 0.1 0.0036 17.0 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin family Acetyltransf_10 PF13673.7 PXF40495.1 - 6.9e-11 42.2 0.0 9.1e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF40495.1 - 4e-06 27.2 0.0 0.00037 20.9 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF40495.1 - 5.6e-05 23.3 0.0 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family PanZ PF12568.8 PXF40495.1 - 0.048 13.4 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ bZIP_2 PF07716.15 PXF40496.1 - 3.1e-05 23.9 2.8 5.2e-05 23.2 2.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF40496.1 - 0.0014 18.7 1.3 0.0019 18.3 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor TPR_1 PF00515.28 PXF40497.1 - 9.5e-07 28.4 11.4 0.48 10.3 0.7 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF40497.1 - 4.7e-06 26.8 0.1 4.7e-06 26.8 0.1 6.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 PXF40497.1 - 8.5e-06 25.5 17.6 0.21 11.8 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF40497.1 - 0.0091 16.3 7.9 15 6.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF40497.1 - 0.022 14.9 11.3 0.3 11.4 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 PXF40497.1 - 1.7 8.8 7.8 2.1 8.4 0.0 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 PXF40497.1 - 2.2 8.8 27.9 6.8 7.3 0.2 7.6 6 2 1 7 7 7 0 Tetratricopeptide repeat WAC_Acf1_DNA_bd PF10537.9 PXF40498.1 - 0.0091 16.5 0.4 0.018 15.5 0.4 1.5 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal NAM-associated PF14303.6 PXF40498.1 - 0.022 15.5 4.8 0.035 14.8 4.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pox_P35 PF03213.14 PXF40498.1 - 0.1 11.8 0.5 0.14 11.3 0.5 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein RBD PF02196.15 PXF40499.1 - 0.042 13.9 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain eIF-3c_N PF05470.12 PXF40500.1 - 1.9e-135 452.5 17.2 4e-87 293.0 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 PXF40500.1 - 9.5e-10 38.9 0.0 3e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain YlbD_coat PF14071.6 PXF40500.1 - 0.0017 18.6 1.1 0.011 16.0 1.1 2.4 1 0 0 1 1 1 1 Putative coat protein SlyX PF04102.12 PXF40501.1 - 2.1e-05 25.1 22.6 0.0011 19.5 8.0 3.9 4 1 1 5 5 5 2 SlyX HALZ PF02183.18 PXF40501.1 - 1.3 9.3 9.0 0.39 11.0 2.7 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF641 PF04859.12 PXF40501.1 - 1.6 9.0 12.5 4.3 7.7 1.8 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DEAD_2 PF06733.15 PXF40501.1 - 2.1 7.9 7.3 0.33 10.6 3.0 1.9 2 0 0 2 2 2 0 DEAD_2 DUF4201 PF13870.6 PXF40501.1 - 2.6 7.8 20.3 24 4.6 4.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) ERM PF00769.19 PXF40501.1 - 2.6 7.8 33.3 7.3 6.3 0.7 3.3 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Tropomyosin PF00261.20 PXF40501.1 - 2.8 7.2 27.6 0.045 13.1 9.8 4.1 3 1 1 4 4 4 0 Tropomyosin TolA_bind_tri PF16331.5 PXF40501.1 - 3.4 7.8 15.7 5.6 7.1 1.2 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation COG2 PF06148.11 PXF40501.1 - 5 7.2 9.5 0.89 9.6 0.3 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 PXF40501.1 - 8.8 6.2 9.6 23 4.8 0.1 3.1 2 1 0 2 2 2 0 Septum formation initiator DEAD PF00270.29 PXF40502.1 - 2.4e-22 79.6 0.0 1e-21 77.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF40502.1 - 4.7e-20 72.0 0.0 2.2e-19 69.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF40502.1 - 0.00029 20.9 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3313 PF11769.8 PXF40502.1 - 0.014 15.2 0.2 6.4 6.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) AAA_22 PF13401.6 PXF40502.1 - 0.031 14.6 0.0 6.8 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AA_kinase PF00696.28 PXF40502.1 - 0.14 11.7 0.3 0.76 9.3 0.3 1.9 1 1 0 1 1 1 0 Amino acid kinase family Mistic PF11458.8 PXF40502.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Branch PF02485.21 PXF40504.1 - 0.015 14.8 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Core-2/I-Branching enzyme Pkinase PF00069.25 PXF40505.1 - 3.9e-71 239.5 0.0 6.1e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40505.1 - 1e-39 136.4 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF40505.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF40505.1 - 0.003 16.9 0.1 0.0058 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF40505.1 - 0.0059 16.2 0.3 0.0059 16.2 0.3 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PXF40505.1 - 0.042 13.8 0.0 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family VanZ PF04892.12 PXF40507.1 - 0.015 16.0 0.5 0.023 15.3 0.5 1.4 1 1 0 1 1 1 0 VanZ like family Virul_fac_BrkB PF03631.15 PXF40507.1 - 0.36 10.4 9.2 0.54 9.8 9.2 1.3 1 0 0 1 1 1 0 Virulence factor BrkB Strabismus PF06638.11 PXF40507.1 - 0.76 8.4 3.8 1 7.9 3.8 1.1 1 0 0 1 1 1 0 Strabismus protein DUF2339 PF10101.9 PXF40507.1 - 1.2 7.6 12.9 1.4 7.4 12.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4231 PF14015.6 PXF40507.1 - 2.1 8.8 5.1 6.8 7.2 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) zf-B_box PF00643.24 PXF40508.1 - 0.00029 20.9 5.3 0.0009 19.3 0.3 2.8 3 0 0 3 3 3 1 B-box zinc finger DUF4712 PF15830.5 PXF40508.1 - 0.15 11.8 1.7 0.15 11.8 0.7 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4712) zinc_ribbon_4 PF13717.6 PXF40508.1 - 0.67 9.9 0.0 0.67 9.9 0.0 3.1 3 1 0 3 3 3 0 zinc-ribbon domain DUF563 PF04577.14 PXF40509.1 - 7.5e-13 49.1 0.0 1.9e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF563) bZIP_2 PF07716.15 PXF40510.1 - 0.018 15.1 8.9 0.032 14.3 8.9 1.3 1 0 0 1 1 1 0 Basic region leucine zipper U1snRNP70_N PF12220.8 PXF40510.1 - 0.023 15.3 2.3 0.041 14.5 2.3 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF3292 PF11696.8 PXF40510.1 - 0.04 12.3 3.0 0.057 11.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) bZIP_1 PF00170.21 PXF40510.1 - 0.07 13.2 6.4 0.12 12.5 6.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor Snf7 PF03357.21 PXF40510.1 - 0.55 9.8 5.5 0.85 9.2 5.5 1.2 1 0 0 1 1 1 0 Snf7 DUF2291 PF10054.9 PXF40510.1 - 3.1 7.5 5.6 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DUF3676 PF12429.8 PXF40510.1 - 7.7 6.3 8.6 0.17 11.7 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3676) SnoaL_3 PF13474.6 PXF40511.1 - 1.8e-20 73.4 0.2 2.4e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 PXF40511.1 - 0.0055 16.9 0.1 0.0088 16.2 0.1 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 PXF40511.1 - 0.73 10.3 3.2 4.6 7.7 3.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Roughex PF06020.11 PXF40512.1 - 0.00054 19.2 12.6 0.001 18.3 12.6 1.4 1 0 0 1 1 1 1 Drosophila roughex protein RskA PF10099.9 PXF40512.1 - 0.0011 19.3 26.4 0.02 15.2 24.6 2.3 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Rrn6 PF10214.9 PXF40512.1 - 0.0035 15.9 16.7 0.0039 15.8 16.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 PXF40512.1 - 0.048 13.6 39.4 0.065 13.2 39.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 PXF40512.1 - 0.18 11.4 9.3 0.26 10.9 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 GREB1 PF15782.5 PXF40512.1 - 0.71 6.9 15.5 0.76 6.8 15.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 PXF40512.1 - 2.2 7.2 20.7 3.3 6.6 20.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 PXF40512.1 - 7 5.9 24.9 7.6 5.8 19.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MTBP_C PF14920.6 PXF40512.1 - 9.6 5.9 18.5 1.1 9.0 13.8 1.6 2 0 0 2 2 2 0 MDM2-binding Chloroa_b-bind PF00504.21 PXF40513.1 - 9e-06 26.3 0.3 1.4e-05 25.7 0.3 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 PXF40514.1 - 0.0066 17.0 0.0 0.01 16.3 0.0 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein DUF2423 PF10338.9 PXF40514.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Ephrin_rec_like PF07699.13 PXF40518.1 - 1.6e-10 40.5 74.1 4e-05 23.3 3.3 9.3 5 4 5 10 10 10 8 Putative ephrin-receptor like NCD3G PF07562.14 PXF40518.1 - 2e-07 30.9 60.9 0.02 14.8 0.5 9.2 4 2 5 10 10 10 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PXF40518.1 - 0.022 15.1 0.2 0.022 15.1 0.2 12.0 8 5 4 13 13 13 0 TNFR/NGFR cysteine-rich region Glycos_transf_2 PF00535.26 PXF40521.1 - 4.3e-12 46.2 0.0 9.5e-12 45.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_4 PF13439.6 PXF40521.1 - 0.0021 18.1 0.0 0.0057 16.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PXF40521.1 - 0.0028 18.1 0.2 1.6 9.2 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain TPT PF03151.16 PXF40522.1 - 3.8e-20 72.4 13.3 7.6e-20 71.4 13.3 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family PS_pyruv_trans PF04230.13 PXF40522.1 - 1.2e-08 35.3 0.0 3.3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide pyruvyl transferase EamA PF00892.20 PXF40522.1 - 1.7e-05 25.0 25.2 2.9e-05 24.3 10.8 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.6 PXF40522.1 - 7.2e-05 22.5 7.5 8.8e-05 22.2 5.4 2.2 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter UAA PF08449.11 PXF40522.1 - 0.5 9.5 11.7 8.3 5.5 11.7 2.3 1 1 0 1 1 1 0 UAA transporter family Glycos_transf_2 PF00535.26 PXF40523.1 - 9.4e-14 51.6 0.0 6.1e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Gb3_synth PF04572.12 PXF40523.1 - 7e-06 26.2 0.0 2.2e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 PXF40523.1 - 0.001 19.7 0.0 0.0039 17.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_tranf_2_2 PF10111.9 PXF40523.1 - 0.012 15.1 0.4 0.049 13.1 0.0 2.2 3 0 0 3 3 3 0 Glycosyltransferase like family 2 OB_NTP_bind PF07717.16 PXF40525.1 - 1.8e-13 50.7 0.1 2.3e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PXF40525.1 - 1.6e-11 44.4 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) DUF2552 PF10827.8 PXF40525.1 - 0.029 14.5 0.1 0.063 13.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2552) RRM_4 PF10598.9 PXF40526.1 - 1.5e-37 127.8 0.0 2.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 U5_2-snRNA_bdg PF10597.9 PXF40527.1 - 2.6e-09 37.2 0.0 4.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 DUF212 PF02681.14 PXF40530.1 - 0.035 14.2 1.1 0.044 13.9 1.1 1.0 1 0 0 1 1 1 0 Divergent PAP2 family OTT_1508_deam PF14441.6 PXF40531.1 - 0.054 13.5 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-C2H2_4 PF13894.6 PXF40532.1 - 3.8e-12 45.9 20.1 0.0059 17.3 1.9 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF40532.1 - 3.6e-10 39.7 21.3 0.0012 19.2 0.9 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF40532.1 - 1.6e-09 37.8 22.9 0.00067 20.0 1.0 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 PXF40532.1 - 0.00016 21.4 6.0 0.11 12.2 0.3 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PXF40532.1 - 0.00034 20.8 6.6 0.006 16.8 0.2 3.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PXF40532.1 - 0.001 19.7 4.3 16 6.2 0.4 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 PXF40532.1 - 0.0021 18.4 3.3 0.86 10.1 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PXF40532.1 - 0.0028 17.9 8.3 0.013 15.8 0.6 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 PXF40532.1 - 0.0056 16.9 2.0 0.0056 16.9 2.0 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 PXF40532.1 - 0.016 15.5 9.3 19 5.6 8.0 3.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 PXF40532.1 - 0.044 13.8 15.2 0.18 11.8 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger DUF4687 PF15747.5 PXF40532.1 - 0.053 14.0 1.2 0.13 12.8 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) C1_4 PF07975.12 PXF40532.1 - 0.059 13.6 8.9 0.37 11.1 1.6 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain BolA PF01722.18 PXF40532.1 - 0.14 12.4 3.1 31 4.9 0.4 3.6 1 1 2 3 3 3 0 BolA-like protein GAGA PF09237.11 PXF40532.1 - 0.14 11.9 5.6 0.26 11.1 0.0 2.8 1 1 1 2 2 2 0 GAGA factor zf_UBZ PF18439.1 PXF40532.1 - 0.36 10.5 6.8 14 5.4 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2197 PF09963.9 PXF40532.1 - 0.63 10.3 11.0 14 6.0 1.3 3.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) RNA_POL_M_15KD PF02150.16 PXF40532.1 - 0.7 9.8 6.5 16 5.5 0.1 3.6 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit DUF629 PF04780.12 PXF40532.1 - 2.2 6.7 10.3 7 5.1 1.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 PXF40532.1 - 2.5 7.8 5.4 21 4.8 0.1 3.4 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 PXF40532.1 - 4.6 7.5 9.6 17 5.7 2.9 3.0 2 1 0 2 2 2 0 LIM domain WXG100 PF06013.12 PXF40534.1 - 0.0063 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF40534.1 - 0.05 13.7 0.3 0.09 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF40534.1 - 0.61 10.8 4.6 1.2 9.8 4.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Sel1 PF08238.12 PXF40535.1 - 4.9e-13 49.3 0.2 0.019 15.7 0.0 8.0 9 0 0 9 9 9 4 Sel1 repeat Endonuclea_NS_2 PF13930.6 PXF40536.1 - 1.6e-13 50.9 0.0 6.7e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease Sel1 PF08238.12 PXF40537.1 - 5e-21 74.7 6.6 0.0085 16.8 0.0 10.3 11 0 0 11 11 11 4 Sel1 repeat TPR_17 PF13431.6 PXF40537.1 - 0.0051 17.1 1.7 12 6.6 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat RIC1 PF07064.13 PXF40537.1 - 0.015 14.7 2.1 1.3 8.3 0.1 3.1 3 0 0 3 3 3 0 RIC1 DUF4253 PF14062.6 PXF40537.1 - 0.12 12.5 0.0 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) TPR_14 PF13428.6 PXF40537.1 - 0.33 11.9 29.7 32 5.7 1.1 9.0 7 3 4 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF40537.1 - 4.8 7.8 26.7 11 6.6 0.4 7.3 6 2 3 9 9 9 0 Tetratricopeptide repeat Glyoxalase PF00903.25 PXF40538.1 - 7.8e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF40538.1 - 0.00044 21.0 0.0 0.00074 20.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Chrome_Resist PF09828.9 PXF40540.1 - 0.17 12.3 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 Chromate resistance exported protein EamA PF00892.20 PXF40541.1 - 1.4e-13 51.1 33.6 2.9e-07 30.8 11.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family GTP_EFTU PF00009.27 PXF40542.1 - 2.7e-69 232.6 0.1 4.8e-69 231.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 PXF40542.1 - 7.7e-35 118.8 0.1 1.8e-34 117.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 PXF40542.1 - 1.5e-25 89.3 0.0 3.3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 PXF40542.1 - 1.6e-17 63.6 1.1 4.6e-17 62.2 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PXF40542.1 - 2e-07 30.9 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 PXF40542.1 - 0.0013 18.8 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PXF40542.1 - 0.0092 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family EFG_C PF00679.24 PXF40543.1 - 2.3e-23 82.0 0.0 2.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Elongation factor G C-terminus FAD-oxidase_C PF02913.19 PXF40544.1 - 1.2e-60 205.2 0.3 1.2e-60 205.2 0.3 2.1 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PXF40544.1 - 2e-39 134.5 0.1 3.4e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2967 PF11179.8 PXF40544.1 - 0.73 7.9 10.3 0.97 7.4 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RAP1 PF07218.11 PXF40544.1 - 8.6 4.5 5.3 3.5 5.8 3.1 1.4 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Aminotran_5 PF00266.19 PXF40545.1 - 6e-42 143.9 0.0 7.2e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PXF40545.1 - 1.7e-05 24.3 0.3 0.0002 20.8 0.0 2.4 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF40545.1 - 0.008 14.7 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 PXF40545.1 - 0.022 14.8 0.0 7.1 6.7 0.0 2.9 2 2 1 3 3 3 0 B12 binding domain Hint PF01079.20 PXF40548.1 - 2.5e-29 102.4 0.3 4.1e-29 101.6 0.3 1.2 1 0 0 1 1 1 1 Hint module Vint PF14623.6 PXF40548.1 - 0.032 14.0 0.1 0.072 12.9 0.1 1.6 1 1 0 1 1 1 0 Hint-domain Hint_2 PF13403.6 PXF40548.1 - 0.033 14.5 0.0 0.28 11.5 0.0 2.2 1 1 1 2 2 2 0 Hint domain Methyltrans_RNA PF04452.14 PXF40549.1 - 2.4e-30 105.6 0.0 8.1e-29 100.6 0.1 2.2 1 1 0 1 1 1 1 RNA methyltransferase Exo_endo_phos PF03372.23 PXF40550.1 - 5.9e-06 26.0 0.0 3.4e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LTD PF00932.19 PXF40551.1 - 2.5e-08 34.3 1.1 6e-06 26.6 0.2 3.0 2 1 0 2 2 2 2 Lamin Tail Domain DUF4202 PF13875.6 PXF40553.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) CHAT PF12770.7 PXF40555.1 - 2e-26 93.1 0.0 1.3e-25 90.4 0.0 2.1 2 1 0 2 2 2 1 CHAT domain Abhydrolase_1 PF00561.20 PXF40558.1 - 6.4e-13 48.9 0.0 9e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF40558.1 - 5.9e-05 23.8 0.2 0.00028 21.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.6 PXF40559.1 - 2.1e-36 125.6 0.1 2.3e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF40559.1 - 1.6e-11 44.3 0.2 2.6e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF40559.1 - 2.8e-11 43.4 0.1 3.9e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF40559.1 - 1e-05 24.7 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PXF40559.1 - 0.0001 21.6 0.1 0.00013 21.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 PXF40559.1 - 0.00075 19.6 0.1 0.0016 18.6 0.1 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 PXF40559.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 PXF40559.1 - 0.016 15.7 0.2 0.023 15.1 0.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Semialdhyde_dh PF01118.24 PXF40559.1 - 0.033 14.6 0.1 0.056 13.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF40559.1 - 0.041 13.9 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 PXF40559.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 PXF40559.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Helicase_C PF00271.31 PXF40561.1 - 1.4e-09 38.3 0.0 3.6e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF40561.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF40561.1 - 0.00052 20.1 0.0 0.0022 18.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3987 PF13148.6 PXF40561.1 - 0.1 11.6 0.0 0.45 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) E3_binding PF02817.17 PXF40563.1 - 0.00018 21.8 0.3 0.00034 20.9 0.3 1.5 1 0 0 1 1 1 1 e3 binding domain MAGE_N PF12440.8 PXF40563.1 - 0.019 15.6 1.6 0.035 14.8 1.6 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal FIST PF08495.10 PXF40564.1 - 2.9e-10 40.4 0.0 3.2e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 FIST N domain DUF676 PF05057.14 PXF40565.1 - 3.2e-11 43.2 0.0 4.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Roughex PF06020.11 PXF40566.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Acetyltransf_3 PF13302.7 PXF40567.1 - 0.043 14.5 0.0 0.077 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF40567.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF40567.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF40568.1 - 0.011 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3158 PF11358.8 PXF40568.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) dsDNA_bind PF01984.20 PXF40569.1 - 0.066 13.5 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Homeodomain PF00046.29 PXF40570.1 - 2.3e-30 104.2 8.7 3.4e-13 49.2 3.1 3.3 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 PXF40570.1 - 1.9e-07 30.9 2.0 0.002 18.0 0.1 2.7 2 0 0 2 2 2 2 Homeobox KN domain YdaS_antitoxin PF15943.5 PXF40570.1 - 2.1e-05 24.3 1.5 0.0076 16.1 0.0 3.7 4 0 0 4 4 4 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 PXF40570.1 - 2.9e-05 23.4 0.9 0.68 9.5 0.0 3.6 3 0 0 3 3 3 2 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.6 PXF40570.1 - 0.00012 21.7 0.0 2.7 7.9 0.0 3.3 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 PXF40570.1 - 0.0012 18.9 0.1 5.4 7.2 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 PXF40570.1 - 0.009 16.1 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix HTH_31 PF13560.6 PXF40570.1 - 0.011 16.0 0.4 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.13 PXF40570.1 - 0.081 12.6 0.1 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain P22_Cro PF14549.6 PXF40570.1 - 0.12 12.2 0.1 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 DNA-binding transcriptional regulator Cro BrkDBD PF09607.10 PXF40570.1 - 1.8 8.4 3.8 7.7 6.4 0.1 2.8 3 0 0 3 3 3 0 Brinker DNA-binding domain CBS PF00571.28 PXF40571.1 - 2.3e-12 47.1 0.1 0.0025 18.2 0.1 3.9 4 1 0 4 4 4 3 CBS domain LSM14 PF12701.7 PXF40572.1 - 1.5e-26 92.3 0.0 2.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain TFIIA PF03153.13 PXF40572.1 - 0.0047 17.0 9.8 0.0067 16.5 9.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SM-ATX PF14438.6 PXF40572.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FDF PF09532.10 PXF40572.1 - 0.027 15.3 2.3 0.027 15.3 2.3 2.9 3 1 1 4 4 4 0 FDF domain PFK PF00365.20 PXF40573.1 - 7.9e-56 189.5 0.5 1e-55 189.1 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 PXF40573.1 - 0.002 17.8 0.0 0.0096 15.5 0.1 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 PXF40573.1 - 0.039 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Tyr_Deacylase PF02580.16 PXF40574.1 - 3.5e-41 141.1 0.0 4e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase CobN-Mg_chel PF02514.16 PXF40575.1 - 2.8e-295 982.4 0.0 4.5e-295 981.7 0.0 1.3 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 PXF40575.1 - 1.4e-41 142.3 0.1 3.5e-41 141.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) UPF0180 PF03698.13 PXF40575.1 - 0.0026 17.9 0.1 11 6.3 0.0 3.6 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0180) DUF2325 PF10087.9 PXF40575.1 - 0.017 15.2 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) zf-4CXXC_R1 PF10497.9 PXF40576.1 - 7.2e-05 22.9 11.5 0.00013 22.1 11.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zinc_ribbon_10 PF10058.9 PXF40576.1 - 0.093 12.5 3.6 0.23 11.2 3.6 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PPR_2 PF13041.6 PXF40577.1 - 5.7e-131 426.6 7.8 1.1e-14 54.4 0.1 13.8 2 1 13 15 15 15 14 PPR repeat family PPR_1 PF12854.7 PXF40577.1 - 6.3e-108 352.1 5.3 1.9e-11 43.4 0.0 14.2 14 0 0 14 14 14 13 PPR repeat PPR PF01535.20 PXF40577.1 - 7.9e-97 311.0 10.4 4.2e-08 32.9 0.0 14.8 15 0 0 15 15 15 14 PPR repeat PPR_3 PF13812.6 PXF40577.1 - 5.3e-90 295.5 0.0 9.9e-15 54.4 0.1 9.4 5 2 5 10 10 10 10 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF40577.1 - 2e-52 177.7 1.9 2.3e-20 72.9 0.0 4.2 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 PXF40577.1 - 3.2e-09 36.1 0.0 0.053 12.4 0.0 4.3 2 2 0 4 4 4 3 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 PXF40577.1 - 2.4e-06 27.4 0.0 0.021 14.7 0.0 4.6 4 1 0 4 4 4 1 Mitochondrial ATPase expression TPR_14 PF13428.6 PXF40577.1 - 9.9e-05 22.8 15.0 33 5.7 0.0 10.1 7 4 5 12 12 11 0 Tetratricopeptide repeat Clathrin PF00637.20 PXF40577.1 - 0.001 18.9 0.0 0.21 11.5 0.0 3.9 3 1 3 6 6 6 1 Region in Clathrin and VPS ECSIT PF06239.11 PXF40577.1 - 0.0014 17.8 0.1 25 3.9 0.0 5.8 3 2 2 7 7 7 0 Evolutionarily conserved signalling intermediate in Toll pathway GMP_synt_C PF00958.22 PXF40577.1 - 0.013 15.5 0.0 6.1 7.0 0.0 4.7 4 2 2 6 6 6 0 GMP synthase C terminal domain TPR_7 PF13176.6 PXF40577.1 - 0.058 13.4 0.1 1.3e+02 3.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 PXF40577.1 - 0.068 13.1 0.0 1e+02 2.7 0.0 4.4 5 1 1 6 6 6 0 Virulence factor membrane-bound polymerase, C-terminal RhlB PF12300.8 PXF40577.1 - 5.4 7.1 12.7 10 6.3 12.7 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB TRM13 PF05206.14 PXF40578.1 - 5.2e-36 124.5 0.1 4e-26 92.1 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-C2H2_9 PF16293.5 PXF40578.1 - 0.29 11.0 2.4 3.8 7.4 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) eIF-5_eIF-2B PF01873.17 PXF40579.1 - 6.6e-35 119.5 0.3 1.3e-34 118.6 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 PXF40579.1 - 8.1e-15 54.7 3.1 8.1e-15 54.7 3.1 3.1 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4952 PF16310.5 PXF40579.1 - 0.083 13.1 0.2 0.23 11.7 0.2 1.7 1 0 0 1 1 1 0 Domian of unknown function (DUF4952) zf-CCHC_2 PF13696.6 PXF40579.1 - 0.89 9.4 3.5 10 6.0 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle HemY_N PF07219.13 PXF40579.1 - 8.9 6.6 8.5 22 5.3 8.5 1.6 1 0 0 1 1 1 0 HemY protein N-terminus ArsA_ATPase PF02374.15 PXF40580.1 - 2.5e-81 273.2 0.1 3.1e-81 272.9 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 PXF40580.1 - 1.3e-10 41.4 0.0 2.6e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 PXF40580.1 - 1.1e-07 31.5 0.9 0.00033 20.2 0.1 2.8 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 PXF40580.1 - 1.2e-06 28.5 0.1 5.7e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 PXF40580.1 - 0.0009 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 PXF40580.1 - 0.0019 17.7 0.1 0.0041 16.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 PXF40580.1 - 0.012 15.3 0.0 0.039 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF40580.1 - 0.029 14.8 0.1 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 PXF40580.1 - 0.037 13.5 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 PXF40580.1 - 0.047 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PXF40580.1 - 0.096 12.3 0.9 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5344 PF17279.2 PXF40580.1 - 0.098 13.2 0.1 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5344) TPT PF03151.16 PXF40581.1 - 6.2e-14 52.0 17.8 7.6e-14 51.7 17.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PXF40581.1 - 2.7e-08 33.4 19.3 3.9e-08 32.9 19.3 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF40581.1 - 5.1e-05 23.5 30.3 0.00017 21.7 9.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Pribosyltran PF00156.27 PXF40583.1 - 9.3e-20 70.7 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Chloroa_b-bind PF00504.21 PXF40584.1 - 4.7e-43 147.5 0.0 6.4e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Methyltransf_4 PF02390.17 PXF40585.1 - 1.8e-35 122.0 0.0 1.8e-34 118.7 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 PXF40585.1 - 0.00017 22.3 0.0 0.00033 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF40585.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PXF40585.1 - 0.046 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PXF40585.1 - 0.061 13.1 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40585.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.31 PXF40586.1 - 0.037 14.2 0.1 0.11 12.8 0.1 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 PXF40587.1 - 9.6e-37 126.8 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40587.1 - 1.7e-14 53.7 0.0 2.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF40587.1 - 6.8e-06 25.6 0.0 1.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF40587.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CLZ PF16526.5 PXF40588.1 - 0.34 11.3 2.7 0.54 10.6 1.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_4 PF02390.17 PXF40589.1 - 1.7e-43 148.1 0.0 2.1e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 PXF40589.1 - 0.00016 22.3 0.0 0.00027 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF40589.1 - 0.0031 17.3 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF40589.1 - 0.016 15.9 0.0 0.042 14.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PXF40589.1 - 0.017 15.0 0.0 0.055 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PXF40589.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 PXF40589.1 - 0.085 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40589.1 - 0.094 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 PXF40589.1 - 0.17 11.4 0.0 0.59 9.6 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 Arf PF00025.21 PXF40590.1 - 1.6e-68 229.6 0.0 1.9e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PXF40590.1 - 5.9e-16 58.8 0.0 8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF40590.1 - 1e-15 57.7 0.0 1.2e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PXF40590.1 - 4.1e-12 45.9 0.1 1.2e-08 34.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PXF40590.1 - 9e-11 41.5 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PXF40590.1 - 6.7e-08 32.2 0.0 9.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF40590.1 - 2.5e-05 24.3 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PXF40590.1 - 0.00057 19.5 0.1 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 PXF40590.1 - 0.0033 16.5 0.2 0.0064 15.5 0.2 1.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CdhD PF03599.16 PXF40590.1 - 0.026 13.3 0.0 0.089 11.5 0.0 1.8 1 1 1 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit FeoB_N PF02421.18 PXF40590.1 - 0.041 13.4 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B 2-Hacid_dh_C PF02826.19 PXF40591.1 - 2.6e-52 176.8 0.0 4.7e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PXF40591.1 - 4.7e-38 129.9 0.1 6.8e-38 129.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PXF40591.1 - 2.5e-05 24.5 0.9 7.3e-05 23.0 0.2 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 PXF40591.1 - 0.062 12.6 0.3 12 5.1 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 PXF40591.1 - 0.063 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 PXF40591.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain NUMOD3 PF07460.11 PXF40592.1 - 3.6e-09 36.7 1.8 5.1e-07 29.8 1.8 2.5 1 1 0 1 1 1 1 NUMOD3 motif (2 copies) DnaJ_CXXCXGXG PF00684.19 PXF40592.1 - 0.017 15.4 12.9 0.046 14.1 12.9 1.8 1 0 0 1 1 1 0 DnaJ central domain Enkurin PF13864.6 PXF40592.1 - 2.9 8.4 12.0 0.65 10.5 5.9 2.2 1 1 1 2 2 2 0 Calmodulin-binding FIST PF08495.10 PXF40593.1 - 3.3e-18 66.3 0.0 3.5e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 FIST N domain FIST_C PF10442.9 PXF40593.1 - 3.4e-16 59.4 0.0 6.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 FIST C domain PRMT5_TIM PF17285.2 PXF40594.1 - 2.3e-65 220.3 0.0 3.3e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 PXF40594.1 - 2e-63 213.3 0.0 2.9e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 PXF40594.1 - 5.2e-52 176.3 1.7 7.8e-52 175.7 1.7 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_31 PF13847.6 PXF40594.1 - 0.00012 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF40594.1 - 0.00013 22.6 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40594.1 - 0.086 13.5 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LBP_BPI_CETP PF01273.25 PXF40595.1 - 4.3e-12 45.9 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain CUE PF02845.16 PXF40595.1 - 0.003 17.2 0.0 0.0071 16.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain Ubie_methyltran PF01209.18 PXF40596.1 - 1.5e-54 184.8 0.0 1.9e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PXF40596.1 - 1.1e-19 70.9 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF40596.1 - 8.5e-19 68.0 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF40596.1 - 2.8e-13 50.0 0.0 3.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF40596.1 - 2.9e-11 44.0 0.0 4.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF40596.1 - 1.1e-10 41.6 0.0 1.5e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF40596.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PXF40596.1 - 0.0037 16.7 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 PXF40596.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 PXF40596.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 PXF40596.1 - 0.02 14.6 0.0 0.05 13.4 0.0 1.5 1 1 0 2 2 2 0 Met-10+ like-protein Methyltransf_18 PF12847.7 PXF40596.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 PXF40596.1 - 0.051 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 PXF40596.1 - 0.052 13.4 0.0 0.35 10.7 0.0 2.3 2 1 0 2 2 2 0 Hypothetical methyltransferase MetW PF07021.12 PXF40596.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 PXF40596.1 - 0.091 11.3 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L23eN PF03939.13 PXF40598.1 - 6.1e-16 58.4 6.0 6.1e-16 58.4 6.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 PXF40598.1 - 1.6e-15 57.2 8.4 1.6e-14 54.0 4.7 2.8 2 1 0 2 2 2 1 Ribosomal protein L23 DUF3000 PF11452.8 PXF40601.1 - 0.011 15.2 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Tnp_DNA_bind PF14706.6 PXF40601.1 - 0.048 13.5 0.4 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 Transposase DNA-binding Peptidase_M20 PF01546.28 PXF40602.1 - 1.5e-34 119.5 0.0 2.2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF40602.1 - 2.9e-05 24.0 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PXF40602.1 - 0.0066 16.2 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Toprim_N PF08275.11 PXF40603.1 - 7.8e-28 97.1 0.0 1.7e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 PXF40603.1 - 5.7e-14 51.7 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 PXF40603.1 - 2.8e-11 43.7 0.0 7.4e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 PXF40603.1 - 6.2e-10 39.4 0.4 1.7e-09 38.0 0.4 1.8 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 PXF40603.1 - 0.00016 21.9 0.1 0.00051 20.2 0.1 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 PXF40603.1 - 0.00088 19.6 0.3 0.0025 18.1 0.0 1.9 2 0 0 2 2 2 1 Toprim domain SpoU_methylase PF00588.19 PXF40604.1 - 6.4e-22 78.3 0.0 8.9e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-RING_11 PF17123.5 PXF40605.1 - 1.1e-07 31.5 3.4 2.4e-07 30.4 3.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 PXF40605.1 - 1.9e-07 31.3 1.7 1.9e-07 31.3 1.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF40605.1 - 2.1e-06 27.5 1.6 2.1e-06 27.5 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF40605.1 - 6.1e-06 26.0 1.5 6.1e-06 26.0 1.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF40605.1 - 3.2e-05 23.9 0.5 3.2e-05 23.9 0.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF40605.1 - 0.0014 18.6 8.9 0.01 15.8 9.0 2.2 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PXF40605.1 - 0.0014 18.2 0.9 0.0014 18.2 0.9 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PXF40605.1 - 0.0031 17.4 8.4 0.023 14.5 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 PXF40605.1 - 0.01 15.2 8.6 0.013 14.9 8.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.7 PXF40605.1 - 0.026 14.8 2.9 0.026 14.8 2.9 3.1 3 1 0 3 3 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PXF40605.1 - 0.045 13.9 0.8 0.045 13.9 0.8 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Consortin_C PF15281.6 PXF40605.1 - 0.05 13.6 1.1 0.089 12.8 1.1 1.4 1 0 0 1 1 1 0 Consortin C-terminus zf-ANAPC11 PF12861.7 PXF40605.1 - 0.056 13.5 3.2 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 PXF40605.1 - 0.06 13.2 3.3 0.25 11.2 0.4 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 PXF40605.1 - 0.067 13.0 1.4 0.33 10.8 1.2 2.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Med19 PF10278.9 PXF40605.1 - 0.24 11.3 8.8 0.48 10.3 8.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FANCL_C PF11793.8 PXF40605.1 - 1.4 9.2 6.6 1.2e+02 2.9 6.6 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain RNase_HII PF01351.18 PXF40606.1 - 1.5e-40 139.2 0.0 2.2e-39 135.3 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease HII Gcw_chp PF09694.10 PXF40606.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Nucleoporin_FG PF13634.6 PXF40607.1 - 0.041 14.7 0.4 0.078 13.8 0.4 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region bZIP_1 PF00170.21 PXF40609.1 - 8.4e-05 22.6 3.7 0.00014 21.9 3.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF40609.1 - 0.0033 17.5 5.3 0.0065 16.5 5.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF40609.1 - 0.13 12.8 4.9 0.06 13.9 2.4 1.6 1 1 1 2 2 2 0 bZIP Maf transcription factor GvpL_GvpF PF06386.11 PXF40609.1 - 0.21 11.5 4.0 0.25 11.2 4.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF 2OG-FeII_Oxy_3 PF13640.6 PXF40610.1 - 7.3e-06 26.8 0.2 2.1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ACOX PF01756.19 PXF40610.1 - 0.087 12.4 0.4 0.14 11.7 0.4 1.3 1 0 0 1 1 1 0 Acyl-CoA oxidase S1FA PF04689.13 PXF40612.1 - 0.05 13.8 0.1 0.05 13.8 0.1 1.8 2 0 0 2 2 2 0 DNA binding protein S1FA Bap31 PF05529.12 PXF40612.1 - 0.21 11.4 1.3 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region Retrotrans_gag PF03732.17 PXF40615.1 - 7.1e-05 23.0 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein PTSIIB_sorb PF03830.15 PXF40615.1 - 0.055 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component SSTK-IP PF15836.5 PXF40615.1 - 3.8 7.7 7.3 9.5 6.4 0.4 3.1 4 0 0 4 4 4 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein S1-P1_nuclease PF02265.16 PXF40616.1 - 0.019 14.8 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 S1/P1 Nuclease Defensin_beta PF00711.19 PXF40616.1 - 1.9 8.6 6.6 8.5 6.5 0.8 3.0 2 0 0 2 2 2 0 Beta defensin Pkinase PF00069.25 PXF40617.1 - 5e-13 49.0 0.0 6.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40617.1 - 1.8e-05 24.2 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF40617.1 - 0.0005 20.1 0.3 0.0022 17.9 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 PXF40617.1 - 0.0013 18.0 0.0 0.003 16.8 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase Kdo PF06293.14 PXF40617.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_21 PF02992.14 PXF40619.1 - 9.7e-09 34.8 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 VWA PF00092.28 PXF40625.1 - 4.1e-05 23.9 0.0 5.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF40625.1 - 0.00036 21.1 0.0 0.00071 20.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF40625.1 - 0.0087 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ferritin-like PF12902.7 PXF40627.1 - 2.2e-45 155.2 0.0 2.9e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like RNA_pol_Rpb2_6 PF00562.28 PXF40628.1 - 7.1e-13 48.4 0.0 9.4e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_5 PF04567.17 PXF40628.1 - 9.3e-11 42.1 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 PXF40628.1 - 3.7e-06 27.1 0.1 7.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 DUF726 PF05277.12 PXF40629.1 - 0.16 10.9 0.1 0.35 9.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF726) ArsA_ATPase PF02374.15 PXF40630.1 - 1.2e-13 50.9 0.4 1.3e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase ArsA_ATPase PF02374.15 PXF40631.1 - 3.1e-18 66.0 0.0 3.1e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase DUF4129 PF13559.6 PXF40631.1 - 0.19 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) adh_short PF00106.25 PXF40633.1 - 2.2e-06 27.3 0.2 3.4e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 PXF40633.1 - 0.036 13.2 0.4 0.073 12.2 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 PXF40633.1 - 0.077 12.4 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GATA PF00320.27 PXF40637.1 - 1.1e-07 31.4 11.2 1.8e-07 30.6 11.2 1.4 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 PXF40638.1 - 2.6e-07 30.1 8.1 4.3e-07 29.4 8.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Radical_SAM PF04055.21 PXF40640.1 - 1.7e-07 31.7 0.0 2.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 PXF40640.1 - 0.0022 18.1 0.1 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 PXF40640.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain PyrI_C PF02748.15 PXF40642.1 - 0.071 13.0 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Sec7 PF01369.20 PXF40643.1 - 1.6e-17 63.8 0.0 3.1e-15 56.3 0.0 2.3 1 1 1 2 2 2 2 Sec7 domain Helicase_C PF00271.31 PXF40644.1 - 2.3e-11 44.0 0.0 4.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PXF40644.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3684 PF12449.8 PXF40646.1 - 6.8e-60 203.0 0.0 1.9e-59 201.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) Cactin_mid PF10312.9 PXF40647.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin Cyto_heme_lyase PF01265.17 PXF40648.1 - 2.5e-56 191.4 15.7 1.3e-55 189.1 15.7 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3105 PF11303.8 PXF40648.1 - 0.011 15.9 0.7 3.2 7.9 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3105) DNA_pol_B_exo1 PF03104.19 PXF40649.1 - 1.3e-09 37.7 0.0 1.6e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo1 PF03104.19 PXF40650.1 - 2.6e-26 92.6 0.0 5.2e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 PXF40650.1 - 1.4e-14 53.7 0.1 6.2e-13 48.3 0.1 3.1 3 1 0 3 3 3 1 DNA polymerase family B RNase_H_2 PF13482.6 PXF40650.1 - 1.2e-07 31.9 0.0 3.6e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 PXF40650.1 - 5.9e-07 29.4 0.0 1.7e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB CCDC144C PF14915.6 PXF40651.1 - 0.034 13.3 0.1 0.065 12.3 0.1 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Ribosomal_L14 PF00238.19 PXF40652.1 - 1.1e-35 122.3 0.2 1.3e-35 122.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ipi1_N PF12333.8 PXF40653.1 - 0.0006 20.4 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation DASH_Ask1 PF08655.10 PXF40653.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Ask1 zf-C3HC4_3 PF13920.6 PXF40654.1 - 0.25 11.2 11.9 0.57 10.1 11.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF40654.1 - 0.47 10.4 14.1 1.2 9.1 14.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.9 PXF40655.1 - 1.3e-22 79.7 0.3 8.4e-20 70.7 0.0 2.8 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Glu_cyclase_2 PF05096.12 PXF40657.1 - 4.6e-85 285.1 0.1 5.8e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase CNOT1_TTP_bind PF16417.5 PXF40658.1 - 1.2e-43 148.5 0.0 1.7e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Imm49 PF15575.6 PXF40658.1 - 0.13 12.0 0.1 15 5.2 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 49 CNOT1_HEAT PF16418.5 PXF40659.1 - 6.1e-09 36.1 0.2 1.1e-08 35.2 0.2 1.5 1 1 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat BLYB PF05289.11 PXF40659.1 - 0.043 14.0 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein TIMP PF00965.17 PXF40660.1 - 4.9e-11 42.8 0.0 7.6e-11 42.1 0.0 1.3 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase Cu-oxidase_3 PF07732.15 PXF40661.1 - 2.7e-38 130.6 2.3 6.3e-38 129.4 0.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PXF40661.1 - 3.1e-35 120.9 7.9 4.9e-33 113.8 1.0 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 PXF40661.1 - 2.4e-27 96.0 0.0 7.1e-27 94.5 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Copper-bind PF00127.20 PXF40661.1 - 0.12 12.9 0.0 0.47 10.9 0.0 2.0 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family FAD_binding_3 PF01494.19 PXF40662.1 - 1.5e-18 67.2 0.0 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PXF40662.1 - 0.0003 20.1 0.0 0.0012 18.1 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF40662.1 - 0.00043 20.0 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF40662.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PXF40662.1 - 0.00093 18.5 0.1 0.025 13.8 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF40662.1 - 0.0046 16.1 0.0 0.048 12.7 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 PXF40662.1 - 0.0053 17.3 0.0 0.07 13.7 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF40662.1 - 0.016 14.3 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 PXF40662.1 - 0.038 14.2 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 PXF40662.1 - 0.041 13.8 0.0 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 PXF40662.1 - 0.087 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.17 PXF40662.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 PXF40662.1 - 0.14 10.8 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein tRNA-synt_1 PF00133.22 PXF40663.1 - 8.3e-71 239.0 0.0 9.8e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF40663.1 - 1.4e-08 33.9 0.0 3.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF40664.1 - 3.2e-82 276.7 0.3 3.7e-82 276.5 0.3 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF40664.1 - 1.9e-06 26.9 0.0 0.00048 19.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PXF40664.1 - 0.016 14.6 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF40664.1 - 0.018 13.9 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DpnD-PcfM PF14207.6 PXF40664.1 - 0.13 12.2 0.6 0.41 10.5 0.6 1.9 1 0 0 1 1 1 0 DpnD/PcfM-like protein HTH_11 PF08279.12 PXF40665.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain EF-hand_1 PF00036.32 PXF40666.1 - 8.8e-10 37.4 0.3 2.7e-06 26.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF40666.1 - 5.6e-07 29.0 0.5 0.02 14.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PXF40666.1 - 8.4e-06 26.2 0.4 0.14 12.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Glyoxalase PF00903.25 PXF40666.1 - 1.3e-05 25.4 0.0 3.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_8 PF13833.6 PXF40666.1 - 3.1e-05 23.7 1.2 0.00032 20.5 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair DUF2306 PF10067.9 PXF40666.1 - 0.085 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) EF-hand_5 PF13202.6 PXF40666.1 - 0.11 12.1 0.6 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 EF hand Glyoxalase_4 PF13669.6 PXF40666.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF40666.1 - 0.15 12.9 0.0 0.45 11.3 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain WXG100 PF06013.12 PXF40667.1 - 0.011 15.9 0.1 0.07 13.4 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF40667.1 - 0.35 11.6 3.8 0.66 10.7 3.8 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PAN_4 PF14295.6 PXF40668.1 - 0.00013 21.8 5.3 0.00039 20.3 5.3 1.9 1 0 0 1 1 1 1 PAN domain UQ_con PF00179.26 PXF40669.1 - 6e-08 32.4 0.0 7.1e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lipoxygenase PF00305.19 PXF40671.1 - 1.8e-48 165.5 0.0 2.7e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase p450 PF00067.22 PXF40672.1 - 6.2e-19 68.1 0.0 3.2e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 YcgR PF07317.12 PXF40673.1 - 0.054 13.4 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Flagellar regulator YcgR AAA_23 PF13476.6 PXF40673.1 - 1.3 9.5 11.4 1.3 9.4 11.4 1.0 1 0 0 1 1 1 0 AAA domain Alpha_GJ PF03229.13 PXF40674.1 - 0.64 10.6 7.2 0.43 11.1 4.2 1.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J CLIP_SPH_Scar PF18399.1 PXF40676.1 - 0.1 12.7 0.4 0.23 11.6 0.4 1.7 1 1 0 1 1 1 0 Clip-domain serine protease homolog Scarface Abhydrolase_1 PF00561.20 PXF40677.1 - 2.2e-20 73.4 0.0 2.9e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF40677.1 - 2e-05 25.3 0.1 2.6e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF40677.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CENP-K PF11802.8 PXF40679.1 - 3.6e-05 23.5 13.6 0.02 14.5 4.5 2.1 1 1 1 2 2 2 2 Centromere-associated protein K Nup54 PF13874.6 PXF40679.1 - 0.013 15.6 1.2 0.013 15.6 1.2 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DNA_topoisoIV PF00521.20 PXF40679.1 - 0.025 13.5 3.7 0.035 13.0 3.7 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A BST2 PF16716.5 PXF40679.1 - 0.11 13.1 6.1 1.6 9.4 0.7 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Spc42p PF11544.8 PXF40679.1 - 0.12 12.4 2.2 3.7 7.6 0.2 2.8 1 1 1 2 2 2 0 Spindle pole body component Spc42p ZapB PF06005.12 PXF40679.1 - 0.13 12.7 13.3 0.49 10.9 1.2 3.5 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_1 PF00170.21 PXF40679.1 - 0.28 11.3 0.2 0.28 11.3 0.2 4.2 3 1 2 5 5 5 0 bZIP transcription factor DUF1664 PF07889.12 PXF40679.1 - 0.67 10.0 6.2 9.9 6.2 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 PXF40679.1 - 1.2 9.5 11.2 2.2 8.7 1.3 2.5 1 1 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 PXF40679.1 - 2.4 8.0 11.1 0.54 10.1 0.1 4.0 3 2 0 4 4 4 0 Septum formation initiator ADIP PF11559.8 PXF40679.1 - 4.8 7.3 11.8 0.74 9.9 1.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 PXF40679.1 - 6 6.9 13.6 0.86 9.7 2.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 PXF40679.1 - 8 6.6 15.8 5.3 7.2 8.6 2.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_lid_1 PF17857.1 PXF40681.1 - 0.021 15.0 1.3 0.15 12.3 0.3 2.4 2 1 0 2 2 2 0 AAA+ lid domain GST_N_3 PF13417.6 PXF40681.1 - 0.028 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Haem_oxygenas_2 PF14518.6 PXF40682.1 - 7.5e-14 51.9 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF3865 PF12981.7 PXF40682.1 - 0.011 15.7 0.7 0.025 14.5 0.7 1.6 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) PPR_2 PF13041.6 PXF40684.1 - 2e-46 156.0 1.1 2.4e-11 43.6 0.1 7.4 3 2 4 7 7 7 6 PPR repeat family PPR_3 PF13812.6 PXF40684.1 - 2.6e-38 129.9 0.1 7.1e-14 51.6 0.0 6.0 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF40684.1 - 4.7e-36 122.2 1.2 9.8e-07 28.4 0.0 9.2 8 1 0 8 8 8 7 PPR repeat PPR PF01535.20 PXF40684.1 - 8.5e-29 97.8 5.8 4.2e-05 23.5 0.1 9.5 9 1 0 9 9 9 6 PPR repeat PPR_long PF17177.4 PXF40684.1 - 3.5e-20 72.3 1.5 1.1e-08 34.7 0.1 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PXF40684.1 - 3.3e-08 33.4 0.0 0.037 13.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial ATPase expression MRP-S27 PF10037.9 PXF40684.1 - 0.0011 17.9 0.0 0.022 13.7 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 PXF40684.1 - 0.017 15.9 0.3 1.2 10.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF40684.1 - 0.13 12.6 0.0 14 6.1 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S21e PF01249.18 PXF40684.1 - 0.15 12.2 0.0 21 5.3 0.0 2.6 1 1 1 2 2 2 0 Ribosomal protein S21e PSP PF04046.16 PXF40684.1 - 0.18 11.7 0.2 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 PSP DUF3452 PF11934.8 PXF40685.1 - 0.01 15.4 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Nse4_C PF08743.10 PXF40685.1 - 0.13 12.5 0.2 1.6 9.0 0.0 2.5 2 1 1 3 3 3 0 Nse4 C-terminal Agenet PF05641.12 PXF40686.1 - 0.075 13.5 0.0 3.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Agenet domain Sel1 PF08238.12 PXF40688.1 - 1.5e-17 63.7 0.4 0.00087 19.9 0.0 8.5 10 0 0 10 10 10 4 Sel1 repeat TPR_6 PF13174.6 PXF40688.1 - 0.00046 20.6 0.1 24 5.8 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF40688.1 - 0.0084 16.9 12.3 14 6.8 0.0 7.2 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF40688.1 - 0.012 15.8 8.6 2.7 8.4 0.2 5.8 4 2 0 5 5 5 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 PXF40689.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF2921 PF11145.8 PXF40691.1 - 0.16 9.8 0.8 0.27 9.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PPR_2 PF13041.6 PXF40692.1 - 1.3e-40 137.3 3.8 9.3e-10 38.6 0.2 5.2 3 2 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 PXF40692.1 - 3.8e-33 113.4 0.3 2.8e-14 52.9 0.0 4.1 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF40692.1 - 6.8e-26 89.7 3.2 1e-06 28.3 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 PXF40692.1 - 2.8e-22 77.3 3.4 6.7e-06 26.0 0.1 6.1 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 PXF40692.1 - 6e-15 55.2 0.5 2.9e-14 52.9 0.5 1.8 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PXF40692.1 - 0.021 14.7 0.0 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression MRP-S27 PF10037.9 PXF40692.1 - 0.023 13.6 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Vps23_core PF09454.10 PXF40692.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Vps23 core domain RPM2 PF08579.11 PXF40692.1 - 0.1 13.0 0.0 3.6 8.0 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) GP57 PF17594.2 PXF40692.1 - 0.12 12.1 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 DUF3342 PF11822.8 PXF40693.1 - 0.042 14.0 0.0 0.05 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DmpG_comm PF07836.11 PXF40694.1 - 0.12 11.9 0.1 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 DmpG-like communication domain DUF4688 PF15752.5 PXF40694.1 - 0.16 11.1 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) AOX PF01786.17 PXF40695.1 - 7.7e-24 84.5 0.2 1.8e-23 83.3 0.0 1.6 2 0 0 2 2 2 1 Alternative oxidase Peptidase_S64 PF08192.11 PXF40695.1 - 0.026 13.0 0.6 0.039 12.4 0.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 AdoHcyase_NAD PF00670.21 PXF40696.1 - 4.5e-46 156.9 0.7 5.3e-46 156.6 0.7 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RXLR_WY PF18634.1 PXF40696.1 - 0.037 14.0 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain 2-Hacid_dh_C PF02826.19 PXF40696.1 - 0.048 13.0 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF40696.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SatD PF16264.5 PXF40697.1 - 0.019 14.6 2.1 0.021 14.5 2.1 1.2 1 0 0 1 1 1 0 SatD family (SatD) Aminotran_5 PF00266.19 PXF40700.1 - 5.9e-40 137.4 0.0 1.1e-39 136.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V SMC_N PF02463.19 PXF40701.1 - 5e-21 75.2 0.0 1.5e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PXF40701.1 - 2.1e-15 57.8 3.5 2.1e-15 57.8 3.5 4.5 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 PXF40701.1 - 2.1e-05 24.1 0.0 6.6e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF40701.1 - 6.2e-05 22.9 2.2 0.00037 20.3 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 PXF40701.1 - 0.0039 17.1 10.8 0.055 13.3 0.3 3.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PXF40701.1 - 0.074 13.5 0.1 0.44 11.0 0.1 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PXF40701.1 - 0.6 10.6 0.0 0.6 10.6 0.0 3.9 3 2 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 PXF40701.1 - 9.9 6.5 13.1 0.75 10.2 0.1 3.8 3 1 0 3 3 3 0 AAA ATPase domain DUF1838 PF08894.11 PXF40703.1 - 2.9e-72 243.2 0.3 4.6e-72 242.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) Cyt-b5 PF00173.28 PXF40703.1 - 4.6e-06 26.7 0.0 2.3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RNase_H2_suC PF08615.11 PXF40703.1 - 0.07 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MLVIN_C PF18697.1 PXF40705.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SPATA3 PF15662.5 PXF40707.1 - 4.2 8.0 18.7 6.8 7.3 16.0 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Spond_N PF06468.13 PXF40709.1 - 2.4e-26 93.0 0.0 3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Spondin_N An_peroxidase PF03098.15 PXF40710.1 - 1.6e-115 386.7 0.1 1.9e-115 386.5 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF40711.1 - 2.3e-101 340.0 0.0 3.2e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF40712.1 - 6.6e-120 401.2 0.0 7.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase NHase_beta PF02211.15 PXF40714.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Cas9_a PF18470.1 PXF40715.1 - 0.081 12.5 0.0 0.093 12.3 0.0 1.0 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain ABC2_membrane PF01061.24 PXF40716.1 - 2.3e-32 112.1 15.2 3.9e-32 111.4 15.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PXF40716.1 - 1.1e-25 90.8 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_2 PF12679.7 PXF40716.1 - 0.0021 17.4 6.5 0.014 14.6 6.5 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PXF40716.1 - 0.006 17.0 0.1 0.015 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PXF40716.1 - 0.0095 16.2 0.1 0.025 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 PXF40716.1 - 0.016 14.3 11.8 0.025 13.7 11.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PXF40716.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 PXF40716.1 - 0.024 14.9 0.1 0.093 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PXF40716.1 - 0.028 15.0 0.0 0.058 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 PXF40716.1 - 0.035 13.1 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 PXF40716.1 - 0.037 13.8 0.2 0.09 12.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 PXF40716.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 PXF40716.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PXF40716.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PXF40716.1 - 0.091 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 PXF40716.1 - 0.11 12.4 0.2 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 PXF40716.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PXF40716.1 - 0.21 11.7 0.3 0.58 10.2 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Glucokinase PF02685.16 PXF40717.1 - 3.9e-85 285.6 0.0 6.7e-85 284.9 0.0 1.4 1 0 0 1 1 1 1 Glucokinase 4HBT PF03061.22 PXF40718.1 - 3.8e-14 52.8 2.7 1.6e-06 28.4 0.5 2.9 3 0 0 3 3 3 2 Thioesterase superfamily Acyl-ACP_TE PF01643.17 PXF40718.1 - 0.005 16.2 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Neisseria_TspB PF05616.13 PXF40719.1 - 1.3 7.5 12.9 1.8 7.0 12.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NAD_kinase PF01513.21 PXF40722.1 - 8.6e-58 195.8 0.0 1.2e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 PXF40722.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BK_channel_a PF03493.18 PXF40723.1 - 1.1e-11 44.7 0.1 1.9e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Mnd1 PF03962.15 PXF40724.1 - 4.9e-07 29.9 1.5 1.6e-05 25.1 1.5 2.1 1 1 0 1 1 1 1 Mnd1 HTH domain NPR3 PF03666.13 PXF40728.1 - 0.01 14.7 3.1 0.011 14.6 3.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RuvX PF03652.15 PXF40728.1 - 0.052 13.9 0.3 0.082 13.3 0.3 1.4 1 1 0 1 1 1 0 Holliday junction resolvase Borrelia_P13 PF05628.12 PXF40733.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Borrelia membrane protein P13 Myb_DNA-binding PF00249.31 PXF40734.1 - 9.5e-07 28.9 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF40734.1 - 0.026 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DndB PF14072.6 PXF40736.1 - 0.011 15.0 0.0 0.064 12.5 0.0 1.9 1 1 1 2 2 2 0 DNA-sulfur modification-associated PIF1 PF05970.14 PXF40737.1 - 1.3e-45 156.2 0.7 1.4e-43 149.5 0.7 2.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 PXF40737.1 - 4.8e-16 59.0 0.1 3.4e-13 49.7 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PXF40737.1 - 2.1e-13 50.8 0.0 5.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 PXF40737.1 - 7.1e-05 20.9 1.1 0.0043 15.1 0.0 2.4 3 0 0 3 3 3 1 Helicase AAA_11 PF13086.6 PXF40737.1 - 8.7e-05 22.4 0.8 0.0014 18.5 0.0 2.9 2 1 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 PXF40737.1 - 9.5e-05 21.5 0.3 0.00015 20.8 0.3 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 PXF40737.1 - 0.00036 20.8 0.1 0.00073 19.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PXF40737.1 - 0.0013 18.6 0.5 0.027 14.4 0.3 2.5 2 0 0 2 2 2 1 NTPase DUF2075 PF09848.9 PXF40737.1 - 0.002 17.5 0.1 0.0031 16.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 PXF40737.1 - 0.0025 17.7 0.4 0.0064 16.4 0.4 1.7 1 1 0 1 1 1 1 Helicase DUF853 PF05872.12 PXF40737.1 - 0.0029 16.2 0.2 0.0043 15.7 0.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.6 PXF40737.1 - 0.003 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PXF40737.1 - 0.0035 16.4 0.3 0.0061 15.6 0.3 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB UvrD-helicase PF00580.21 PXF40737.1 - 0.0067 16.0 0.4 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 PXF40737.1 - 0.0091 15.8 0.1 0.042 13.7 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 PXF40737.1 - 0.016 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 PXF40737.1 - 0.017 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KdpD PF02702.17 PXF40737.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 2 0 0 2 2 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_16 PF13191.6 PXF40737.1 - 0.02 15.3 0.1 0.036 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 PXF40737.1 - 0.025 14.5 0.3 0.048 13.5 0.3 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 PXF40737.1 - 0.026 14.2 0.5 0.046 13.3 0.5 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 PXF40737.1 - 0.028 14.5 1.4 0.064 13.3 1.4 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 PXF40737.1 - 0.04 13.0 0.6 0.075 12.1 0.6 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 PXF40737.1 - 0.055 12.9 0.0 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.18 PXF40737.1 - 0.087 12.5 1.7 0.28 10.9 0.3 2.6 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PXF40737.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 PXF40737.1 - 0.17 11.9 0.1 0.75 9.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 PXF40737.1 - 2.3 8.0 6.5 0.55 10.0 0.4 2.7 3 1 0 4 4 4 0 DEAD/DEAH box helicase RNB PF00773.19 PXF40739.1 - 3.5e-30 105.5 0.0 2.1e-08 33.9 0.0 4.8 3 1 1 4 4 4 3 RNB domain RRM_1 PF00076.22 PXF40741.1 - 3.9e-14 52.2 0.0 5.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Epimerase PF01370.21 PXF40742.1 - 5.2e-06 26.1 0.1 3.1e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF40742.1 - 0.0021 17.5 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Dehalogenase PF13486.6 PXF40742.1 - 0.17 11.2 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit ATG101 PF07855.12 PXF40743.1 - 0.011 15.7 0.2 0.023 14.7 0.0 1.5 1 1 1 2 2 2 0 Autophagy-related protein 101 Picorna_P3A PF06363.11 PXF40743.1 - 0.089 12.7 0.5 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein LCM PF04072.14 PXF40744.1 - 4.7e-09 36.5 0.0 1.2e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase PIN_10 PF18478.1 PXF40744.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 PIN like domain WD40 PF00400.32 PXF40745.1 - 4.3e-20 71.7 9.7 1e-08 35.6 0.2 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40745.1 - 0.00012 22.2 0.1 0.24 11.7 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 PXF40746.1 - 3.7e-154 514.0 4.9 4.2e-154 513.8 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ORC_WH_C PF18137.1 PXF40747.1 - 1.9e-20 73.3 0.0 1.6e-18 67.1 0.0 2.6 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 PXF40747.1 - 1.9e-14 53.5 0.1 2.5e-09 36.7 0.0 3.0 2 1 1 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus Microcephalin PF12258.8 PXF40747.1 - 0.24 10.6 0.3 0.35 10.1 0.3 1.1 1 0 0 1 1 1 0 Microcephalin protein RRM_1 PF00076.22 PXF40748.1 - 2.9e-24 84.7 0.0 5.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 PXF40748.1 - 7.4e-11 41.5 0.6 3.5e-10 39.3 0.6 2.2 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 PXF40748.1 - 1.6e-09 38.1 3.0 5.5e-09 36.3 3.0 2.0 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 PXF40748.1 - 0.03 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DNA_ligase_IV PF11411.8 PXF40748.1 - 0.046 13.9 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA ligase IV RRM_5 PF13893.6 PXF40748.1 - 0.047 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NYD-SP28 PF14772.6 PXF40749.1 - 0.13 12.3 1.1 0.29 11.2 1.1 1.6 1 0 0 1 1 1 0 Sperm tail Cpn60_TCP1 PF00118.24 PXF40750.1 - 3.1e-145 484.6 9.3 3.7e-145 484.3 9.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Membralin PF09746.9 PXF40751.1 - 1.4e-14 54.0 16.2 1.8e-11 43.8 11.6 3.0 2 1 0 2 2 2 2 Tumour-associated protein Clp1 PF06807.14 PXF40752.1 - 1.7e-27 96.2 0.1 2.9e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 PXF40752.1 - 2.5e-27 95.9 0.0 3.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 PXF40752.1 - 4.8e-23 81.2 0.0 7.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor DUF3150 PF11348.8 PXF40752.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) SRPRB PF09439.10 PXF40752.1 - 0.091 12.2 0.0 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PXF40752.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain BRCT_2 PF16589.5 PXF40754.1 - 5.3e-09 36.4 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PXF40754.1 - 3.4e-05 24.2 0.7 0.8 10.1 0.0 3.5 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 PXF40754.1 - 0.011 15.8 0.0 3.9 7.6 0.0 2.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DciA PF05258.12 PXF40754.1 - 0.17 12.3 0.3 0.35 11.3 0.3 1.4 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA zf-B_box PF00643.24 PXF40754.1 - 0.4 10.9 4.6 0.92 9.7 4.6 1.6 1 0 0 1 1 1 0 B-box zinc finger YidD PF01809.18 PXF40755.1 - 6.3e-25 86.8 0.1 7.9e-25 86.5 0.1 1.1 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor NinE PF05322.11 PXF40755.1 - 0.069 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 NINE Protein Thioredoxin PF00085.20 PXF40756.1 - 7.2e-25 87.0 0.0 8.8e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF40756.1 - 1.9e-09 37.9 0.1 4.7e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PXF40756.1 - 1e-06 28.9 0.0 0.00016 22.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 PXF40756.1 - 0.0017 18.0 0.1 0.0065 16.2 0.1 1.8 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 PXF40756.1 - 0.0023 17.8 0.1 0.0073 16.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 PXF40756.1 - 0.0029 17.7 0.4 0.0086 16.2 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 PXF40756.1 - 0.0055 16.1 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_5 PF13743.6 PXF40756.1 - 0.01 15.5 0.1 0.033 13.9 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 PXF40756.1 - 0.023 14.9 0.0 0.053 13.8 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 PXF40756.1 - 0.061 13.1 0.3 0.43 10.3 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 PXF40756.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain DUF953 PF06110.11 PXF40756.1 - 0.065 12.9 0.3 0.19 11.4 0.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 PXF40756.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein RRM_1 PF00076.22 PXF40757.1 - 9.4e-21 73.4 0.0 4.3e-07 29.7 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 PXF40757.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 Exonuclease Telomere_res PF16684.5 PXF40757.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Telomere resolvase DUF1350 PF07082.11 PXF40758.1 - 3.4e-35 121.5 0.2 1.1e-33 116.6 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.7 PXF40758.1 - 0.0004 21.0 0.3 0.00061 20.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family bZIP_2 PF07716.15 PXF40759.1 - 2.1e-05 24.5 9.0 4.1e-05 23.6 9.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF40759.1 - 0.0028 17.7 8.8 0.0055 16.8 8.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF641 PF04859.12 PXF40759.1 - 0.014 15.7 1.0 0.024 15.0 1.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) GON PF08685.11 PXF40759.1 - 0.028 14.3 0.4 0.05 13.5 0.4 1.3 1 0 0 1 1 1 0 GON domain SlyX PF04102.12 PXF40759.1 - 0.065 13.9 1.5 0.065 13.9 1.5 2.2 2 0 0 2 2 2 0 SlyX WDCP PF15390.6 PXF40759.1 - 0.077 11.4 0.5 0.1 11.0 0.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PKcGMP_CC PF16808.5 PXF40759.1 - 0.12 12.2 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HIP1_clath_bdg PF16515.5 PXF40759.1 - 0.34 11.6 5.3 0.69 10.6 5.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5593 PF18007.1 PXF40759.1 - 0.51 11.1 2.9 0.52 11.0 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5593) TFIIA PF03153.13 PXF40759.1 - 2.8 7.9 9.4 3.5 7.5 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med26 PF08711.11 PXF40760.1 - 5.7e-06 26.3 0.4 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ORC2 PF04084.14 PXF40760.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.5 1 1 1 2 2 2 0 Origin recognition complex subunit 2 Pkinase PF00069.25 PXF40761.1 - 5e-24 85.1 0.0 6.7e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40761.1 - 8.1e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF40761.1 - 2.6e-08 33.1 0.1 4.4e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF40761.1 - 0.00016 21.7 0.0 0.00046 20.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF40761.1 - 0.097 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.28 PXF40762.1 - 6.3e-67 226.0 0.0 7.4e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF40762.1 - 1.4e-14 54.8 0.1 3.4e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain STAT_alpha PF01017.20 PXF40763.1 - 0.0025 17.7 5.5 0.0038 17.2 5.5 1.2 1 0 0 1 1 1 1 STAT protein, all-alpha domain NRBF2 PF08961.10 PXF40763.1 - 0.0051 16.4 1.1 0.0076 15.9 1.1 1.3 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Golgin_A5 PF09787.9 PXF40763.1 - 0.012 15.1 4.9 0.018 14.5 4.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4618 PF15397.6 PXF40763.1 - 0.018 14.4 4.8 0.03 13.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CCDC158 PF15921.5 PXF40763.1 - 0.019 12.8 2.6 0.024 12.5 2.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Nup54 PF13874.6 PXF40763.1 - 0.024 14.7 6.2 0.051 13.7 4.9 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 PXF40763.1 - 0.025 13.9 8.4 0.074 12.3 8.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 PXF40763.1 - 0.026 14.1 5.3 0.05 13.2 5.4 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain YabA PF06156.13 PXF40763.1 - 0.033 14.8 7.1 0.12 13.1 3.3 3.0 2 1 1 3 3 2 0 Initiation control protein YabA ZapB PF06005.12 PXF40763.1 - 0.035 14.6 4.4 0.035 14.6 4.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 PXF40763.1 - 0.038 14.2 1.8 2.1 8.7 0.2 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain Snf7 PF03357.21 PXF40763.1 - 0.055 13.1 7.1 0.18 11.4 1.4 2.3 2 0 0 2 2 2 0 Snf7 KASH_CCD PF14662.6 PXF40763.1 - 0.062 13.1 9.2 0.18 11.6 9.1 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 PXF40763.1 - 0.068 13.7 5.3 0.13 12.7 5.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Taxilin PF09728.9 PXF40763.1 - 0.076 12.2 8.8 0.14 11.3 8.8 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein AAA_13 PF13166.6 PXF40763.1 - 0.082 11.5 4.0 0.11 11.1 4.0 1.1 1 0 0 1 1 1 0 AAA domain APC_N_CC PF16689.5 PXF40763.1 - 0.13 12.3 4.1 1.5 8.9 2.1 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cnn_1N PF07989.11 PXF40763.1 - 0.14 12.3 7.6 1.1 9.4 3.0 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 PXF40763.1 - 0.15 12.2 4.7 0.13 12.4 1.5 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 PXF40763.1 - 0.17 11.7 14.1 2.3 8.1 0.4 3.5 2 1 1 3 3 3 0 Septum formation initiator WXG100 PF06013.12 PXF40763.1 - 0.18 12.0 4.0 5.3 7.4 0.2 2.5 1 1 0 2 2 2 0 Proteins of 100 residues with WXG TSC22 PF01166.18 PXF40763.1 - 0.2 12.0 3.9 1.9 8.9 1.7 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family FapA PF03961.13 PXF40763.1 - 0.28 9.7 2.2 0.43 9.1 2.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 PXF40763.1 - 0.3 11.1 7.5 0.55 10.3 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2968 PF11180.8 PXF40763.1 - 0.34 10.5 8.9 0.47 10.1 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FlgN PF05130.12 PXF40763.1 - 0.34 11.4 6.2 1.3 9.5 0.3 2.2 1 1 1 2 2 2 0 FlgN protein CLZ PF16526.5 PXF40763.1 - 0.51 10.7 7.5 3.8 7.9 0.7 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 PXF40763.1 - 0.51 10.4 9.9 0.41 10.7 5.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 PXF40763.1 - 0.63 10.2 6.9 1.6 8.9 3.8 2.5 1 1 1 2 2 2 0 bZIP transcription factor Syntaxin-6_N PF09177.11 PXF40763.1 - 0.65 10.6 6.4 18 5.9 1.6 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal eIF3_N PF09440.10 PXF40763.1 - 0.72 10.3 6.5 1.1 9.7 0.9 2.4 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Fib_alpha PF08702.10 PXF40763.1 - 0.79 9.9 6.9 1.4 9.1 6.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 PXF40763.1 - 0.94 9.8 7.0 0.74 10.1 0.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 PXF40763.1 - 0.98 9.6 9.2 0.72 10.0 3.8 2.2 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 PXF40763.1 - 0.99 9.8 10.6 2.6 8.5 5.7 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain Plasmid_RAQPRD PF09686.10 PXF40763.1 - 1.1 9.5 3.5 1 9.6 0.5 2.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) FlaC_arch PF05377.11 PXF40763.1 - 1.2 9.6 5.6 9.5 6.7 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 PXF40763.1 - 1.3 9.9 8.8 2.2 9.2 8.1 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Laminin_II PF06009.12 PXF40763.1 - 1.5 8.8 8.0 2.9 7.9 8.0 1.5 1 1 0 1 1 1 0 Laminin Domain II Ax_dynein_light PF10211.9 PXF40763.1 - 2.9 7.8 9.5 2.2 8.2 3.2 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-H PF05837.12 PXF40763.1 - 3.7 8.0 9.2 1.3 9.5 5.1 2.1 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Lectin_N PF03954.14 PXF40763.1 - 4 7.2 7.2 0.5 10.1 2.4 2.0 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain DUF4795 PF16043.5 PXF40763.1 - 4.3 6.9 9.6 93 2.5 9.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc24 PF08286.11 PXF40763.1 - 9.3 6.5 9.6 7.3 6.9 2.5 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 AD PF09793.9 PXF40764.1 - 1.5e-20 73.1 0.0 2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Myb_DNA-binding PF00249.31 PXF40765.1 - 3.1e-11 43.3 0.1 5.1e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Trypan_PARP PF05887.11 PXF40765.1 - 0.0048 16.9 13.1 0.0048 16.9 13.1 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 PXF40765.1 - 0.051 12.7 2.6 0.11 11.7 2.6 1.5 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Myb_DNA-bind_6 PF13921.6 PXF40765.1 - 0.055 13.7 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF40765.1 - 0.093 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Neisseria_TspB PF05616.13 PXF40765.1 - 0.76 8.2 9.1 1.3 7.5 9.1 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LXG PF04740.12 PXF40766.1 - 0.019 14.7 3.0 0.028 14.1 3.0 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily Phasin PF05597.11 PXF40766.1 - 0.021 14.8 0.4 0.028 14.4 0.4 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5082 PF16888.5 PXF40766.1 - 0.023 15.0 0.7 0.031 14.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) CdvA PF18822.1 PXF40766.1 - 0.024 14.5 0.6 0.042 13.7 0.6 1.5 1 1 0 1 1 1 0 CdvA-like coiled-coil domain BssS PF13991.6 PXF40766.1 - 0.024 14.7 1.5 0.11 12.6 0.2 2.0 1 1 1 2 2 2 0 BssS protein family CLZ PF16526.5 PXF40766.1 - 0.025 14.9 3.2 0.026 14.9 1.4 1.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIVA PF05103.13 PXF40766.1 - 0.026 14.6 3.0 0.035 14.2 3.0 1.1 1 0 0 1 1 1 0 DivIVA protein Apolipoprotein PF01442.18 PXF40766.1 - 0.035 14.0 2.6 0.055 13.4 2.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spo0A_C PF08769.11 PXF40766.1 - 0.042 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Baculo_PEP_C PF04513.12 PXF40766.1 - 0.049 13.7 1.8 0.1 12.7 1.8 1.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad3 PF08656.10 PXF40766.1 - 0.055 13.6 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 Elongin_A PF06881.11 PXF40766.1 - 0.085 13.4 0.1 0.12 13.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PCAF_N PF06466.11 PXF40766.1 - 0.085 12.4 0.2 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF1340 PF07067.11 PXF40766.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) DUF4525 PF15027.6 PXF40766.1 - 0.11 12.2 0.2 0.37 10.5 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4525) SAP130_C PF16014.5 PXF40766.1 - 0.18 10.9 6.0 0.17 11.0 6.0 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Fzo_mitofusin PF04799.13 PXF40766.1 - 0.18 11.4 1.9 0.24 11.0 1.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1053 PF06327.14 PXF40766.1 - 0.35 11.4 2.2 4.3 7.9 0.6 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Vps51 PF08700.11 PXF40767.1 - 4.2e-07 30.0 0.1 2.2e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DUF883 PF05957.13 PXF40767.1 - 0.016 15.8 7.4 0.064 13.9 0.0 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Svf1_C PF17187.4 PXF40767.1 - 0.15 11.9 0.2 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain Sigma70_ner PF04546.13 PXF40768.1 - 1.2 9.0 8.1 4 7.3 0.1 2.5 1 1 1 2 2 2 0 Sigma-70, non-essential region Methyltransf_28 PF02636.17 PXF40769.1 - 2.9e-32 112.3 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 PXF40769.1 - 0.00043 19.4 0.0 0.00063 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 PXF40769.1 - 0.0023 17.8 0.0 0.0047 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain zf-RING_13 PF17977.1 PXF40769.1 - 0.013 15.6 0.1 0.15 12.3 0.0 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Methyltransf_12 PF08242.12 PXF40769.1 - 0.023 15.4 0.1 0.092 13.5 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_20 PF12147.8 PXF40769.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 PXF40769.1 - 0.068 13.9 0.0 0.21 12.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 PXF40769.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 PXF40769.1 - 0.079 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-oxoacid_dh PF00198.23 PXF40770.1 - 6.8e-82 274.4 0.0 8.9e-82 274.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PXF40770.1 - 1.3e-15 56.9 1.3 2.2e-15 56.2 1.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PXF40770.1 - 0.00036 20.3 0.7 0.00036 20.3 0.7 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like Ribosomal_60s PF00428.19 PXF40770.1 - 0.12 13.0 8.3 0.35 11.5 8.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein HlyD_D23 PF16576.5 PXF40770.1 - 0.21 10.8 1.8 5 6.3 0.1 2.4 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 PXF40770.1 - 0.29 11.9 5.1 0.67 10.7 0.5 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Chorion_2 PF03964.15 PXF40770.1 - 3.1 8.7 4.9 5.9 7.8 4.9 1.4 1 0 0 1 1 1 0 Chorion family 2 HSP70 PF00012.20 PXF40771.1 - 7e-115 384.5 0.1 2.5e-114 382.7 0.1 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PXF40771.1 - 1e-06 27.8 0.1 1.9e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 PXF40771.1 - 0.0045 17.4 1.3 0.8 10.2 0.4 3.0 2 1 0 2 2 2 2 Cell division protein FtsA DUF5028 PF16431.5 PXF40771.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) Hint PF01079.20 PXF40772.1 - 2e-17 63.4 0.0 4.5e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 Hint module PT-HINT PF07591.11 PXF40772.1 - 0.029 14.6 0.0 0.34 11.1 0.0 2.2 1 1 0 1 1 1 0 Pretoxin HINT domain Vint PF14623.6 PXF40772.1 - 0.041 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Hint-domain Herpes_UL49_5 PF05702.11 PXF40773.1 - 0.059 13.5 4.1 0.075 13.1 0.1 2.7 2 2 1 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein GLTT PF01744.20 PXF40773.1 - 0.076 12.8 0.2 0.076 12.8 0.2 2.3 2 0 0 2 2 2 0 GLTT repeat (6 copies) 2OG-FeII_Oxy_3 PF13640.6 PXF40774.1 - 6.5e-05 23.8 0.0 0.00013 22.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PXF40774.1 - 0.029 15.0 0.0 0.066 13.9 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RICTOR_M PF14666.6 PXF40774.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain AdoHcyase_NAD PF00670.21 PXF40775.1 - 5.3e-27 94.9 2.4 7.5e-27 94.4 2.4 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 PXF40775.1 - 2.5e-13 49.8 0.0 2.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 PXF40775.1 - 0.0042 16.5 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PXF40775.1 - 0.038 13.6 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AbiEi_3 PF11459.8 PXF40776.1 - 0.0034 17.1 0.7 0.015 15.0 0.1 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system zf-primase PF09329.11 PXF40777.1 - 1.5e-09 37.5 0.5 2.9e-09 36.6 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger BSMAP PF12280.8 PXF40777.1 - 0.1 12.8 2.5 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Brain specific membrane anchored protein Cupin_2 PF07883.11 PXF40778.1 - 2.8e-10 39.8 0.0 4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 PXF40778.1 - 4e-05 23.5 0.0 8.5e-05 22.5 0.0 1.5 1 1 1 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 PXF40778.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase WD40 PF00400.32 PXF40779.1 - 5e-06 27.1 0.8 0.51 11.3 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF40779.1 - 0.00011 22.4 0.1 0.067 13.5 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PXF40779.1 - 0.0038 17.7 0.0 45 4.7 0.0 4.6 4 0 0 4 4 4 1 PQQ-like domain Syntaxin PF00804.25 PXF40780.1 - 8.9e-28 97.3 9.7 1.4e-27 96.6 9.7 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 PXF40780.1 - 5.7e-16 58.3 6.7 4.1e-15 55.5 0.3 3.5 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 PXF40780.1 - 0.0011 19.3 2.2 0.0011 19.3 2.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein DUF4407 PF14362.6 PXF40780.1 - 0.13 11.6 12.1 51 3.1 12.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 PXF40780.1 - 0.18 11.6 12.0 0.36 10.6 1.2 3.2 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF2353 PF09789.9 PXF40780.1 - 0.3 10.4 14.7 1.2 8.5 9.5 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) FlaC_arch PF05377.11 PXF40780.1 - 1.3 9.5 8.5 0.29 11.6 1.4 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4071 PF13281.6 PXF40780.1 - 1.4 7.9 6.6 1.4 7.9 0.7 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4071) PRKG1_interact PF15898.5 PXF40780.1 - 2.8 8.9 15.1 2.3 9.1 4.5 2.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 PXF40780.1 - 3.1 7.8 8.6 0.54 10.3 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) HI0933_like PF03486.14 PXF40781.1 - 3.7e-86 289.4 0.0 1.1e-78 264.8 0.0 2.0 1 1 1 2 2 2 2 HI0933-like protein GIDA PF01134.22 PXF40781.1 - 5.5e-08 32.3 4.0 0.0055 15.8 1.4 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PXF40781.1 - 2.9e-07 30.0 0.0 5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF40781.1 - 1.8e-06 28.0 1.7 2.6e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 PXF40781.1 - 5e-05 22.6 4.3 0.00056 19.1 1.8 2.8 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 PXF40781.1 - 0.00014 21.3 0.1 0.00025 20.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 PXF40781.1 - 0.00029 20.5 3.2 0.1 12.1 0.9 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PXF40781.1 - 0.00047 19.5 0.0 0.0071 15.6 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PXF40781.1 - 0.00059 19.3 1.6 0.0011 18.5 1.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF40781.1 - 0.001 19.3 0.3 0.0035 17.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PXF40781.1 - 0.0025 16.7 1.2 0.011 14.6 0.5 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.24 PXF40781.1 - 0.0082 15.5 0.1 0.034 13.5 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 PXF40781.1 - 0.052 12.6 1.8 0.09 11.8 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 PXF40781.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Methyltransf_34 PF11312.8 PXF40781.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase SIR2 PF02146.17 PXF40782.1 - 1.4e-52 178.2 0.0 2.2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PXF40782.1 - 0.00069 19.4 0.8 0.82 9.4 0.0 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain CCDC24 PF15669.5 PXF40782.1 - 0.089 12.7 0.8 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 PXF40782.1 - 0.15 11.7 4.2 0.27 10.8 4.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 PXF40782.1 - 0.24 11.7 12.7 0.6 10.5 12.7 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain Pap_E4 PF02711.14 PXF40782.1 - 0.29 12.1 13.2 0.2 12.6 9.2 2.4 2 0 0 2 2 2 0 E4 protein PH PF00169.29 PXF40784.1 - 5.1e-05 23.7 0.1 7.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 PH domain HhH-GPD PF00730.25 PXF40785.1 - 7.3e-18 65.0 0.0 1.9e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PXF40785.1 - 0.00095 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pneumo_att_G PF05539.11 PXF40785.1 - 5 6.6 21.3 9.3 5.7 21.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Cyclin PF08613.11 PXF40786.1 - 2.6e-25 89.7 0.1 3e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF40786.1 - 4.7e-09 36.1 0.4 8.3e-09 35.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ATG16 PF08614.11 PXF40787.1 - 0.0019 18.5 19.5 0.0019 18.5 19.5 2.0 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.6 PXF40787.1 - 0.0028 17.0 7.6 0.0073 15.7 7.6 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 PXF40787.1 - 0.013 13.7 6.2 0.019 13.2 6.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 PXF40787.1 - 0.018 14.4 12.8 0.036 13.4 10.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 PXF40787.1 - 0.042 12.8 5.3 0.069 12.1 5.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HOOK PF05622.12 PXF40787.1 - 0.048 11.8 8.0 0.067 11.3 8.0 1.2 1 0 0 1 1 1 0 HOOK protein Prefoldin_2 PF01920.20 PXF40787.1 - 0.054 13.5 9.7 31 4.6 9.7 3.1 1 1 0 1 1 1 0 Prefoldin subunit DUF3584 PF12128.8 PXF40787.1 - 0.08 10.5 10.9 0.11 10.0 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DHR10 PF18595.1 PXF40787.1 - 0.083 13.0 18.4 0.12 12.4 12.9 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 PXF40787.1 - 0.097 12.8 9.5 0.036 14.2 4.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nup54 PF13874.6 PXF40787.1 - 0.098 12.8 18.0 0.03 14.4 12.7 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF724 PF05266.14 PXF40787.1 - 0.13 12.1 5.8 0.044 13.6 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 PXF40787.1 - 0.13 12.2 6.7 0.38 10.8 2.2 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF4201 PF13870.6 PXF40787.1 - 0.16 11.7 10.1 0.61 9.8 10.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 PXF40787.1 - 0.24 10.2 7.0 0.37 9.6 7.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 PXF40787.1 - 0.41 11.0 5.2 0.9 9.9 5.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 PXF40787.1 - 0.44 9.1 1.1 0.52 8.9 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 PXF40787.1 - 0.54 10.5 8.7 0.31 11.3 1.7 2.8 1 1 0 2 2 2 0 ABC transporter C-terminal domain SHE3 PF17078.5 PXF40787.1 - 0.85 9.3 12.4 0.021 14.6 4.3 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 FlxA PF14282.6 PXF40787.1 - 0.88 9.6 14.1 4.5 7.3 1.3 2.6 1 1 1 2 2 2 0 FlxA-like protein DUF1664 PF07889.12 PXF40787.1 - 0.88 9.6 3.8 2.1 8.4 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 PXF40787.1 - 1 9.7 9.5 0.18 12.2 4.4 2.1 2 0 0 2 2 2 0 Syntaxin-like protein SlyX PF04102.12 PXF40787.1 - 1.1 9.9 21.2 2.1 9.0 2.8 4.0 2 1 2 4 4 4 0 SlyX DUF4763 PF15960.5 PXF40787.1 - 1.9 7.7 27.0 0.86 8.9 8.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) Fez1 PF06818.15 PXF40787.1 - 2.3 8.6 12.5 4 7.8 11.5 2.0 1 1 0 1 1 1 0 Fez1 Fmp27_WPPW PF10359.9 PXF40787.1 - 2.4 6.9 9.2 14 4.4 9.1 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Uso1_p115_C PF04871.13 PXF40787.1 - 3.4 8.0 10.7 2.9 8.3 8.5 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 PXF40787.1 - 5.1 7.6 13.7 9.4 6.8 13.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 PXF40787.1 - 5.9 6.5 20.5 10 5.7 18.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF948 PF06103.11 PXF40787.1 - 7.3 6.9 6.0 1.2e+02 3.0 5.6 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ribonuclease_T2 PF00445.18 PXF40788.1 - 6.1e-32 111.3 0.0 8.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.6 PXF40789.1 - 0.00012 22.4 6.3 0.0019 18.5 1.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 PXF40789.1 - 0.00096 19.5 12.9 0.0021 18.4 5.5 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF759 PF05537.11 PXF40789.1 - 0.11 11.4 2.3 0.16 10.8 2.3 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) zf-C2H2_6 PF13912.6 PXF40789.1 - 0.43 10.6 6.8 0.19 11.8 3.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 PXF40789.1 - 0.55 10.7 1.8 1.2 9.6 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF40789.1 - 1.2 9.5 4.6 0.77 10.1 2.5 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PXF40789.1 - 2 9.5 8.7 3 8.9 3.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ran_BP1 PF00638.18 PXF40790.1 - 1.5e-23 83.4 0.3 2.5e-23 82.6 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 PXF40790.1 - 1.5e-13 51.2 2.9 1.5e-13 51.2 2.9 2.7 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) WH1 PF00568.23 PXF40790.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 WH1 domain Dala_Dala_lig_N PF01820.21 PXF40790.1 - 0.043 14.3 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Sec7 PF01369.20 PXF40791.1 - 2.1e-71 239.4 0.0 9.1e-71 237.3 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 PXF40791.1 - 1.3e-34 119.4 1.9 2.7e-34 118.3 0.3 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PXF40791.1 - 8.5e-31 105.7 0.5 1.6e-28 98.4 0.1 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 PXF40791.1 - 6.6e-25 87.8 0.2 6.7e-23 81.3 0.1 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 PXF40791.1 - 0.03 12.5 0.1 0.057 11.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of Mon2 protein HEAT PF02985.22 PXF40791.1 - 1.4 9.4 6.8 80 3.9 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat Rab3-GTPase_cat PF13890.6 PXF40792.1 - 4.1e-37 127.3 2.4 8.7e-37 126.3 2.4 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit zf-RING_2 PF13639.6 PXF40793.1 - 7.8e-13 48.5 8.1 7.8e-13 48.5 8.1 1.8 2 1 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 PXF40793.1 - 6.9e-10 38.5 1.0 6.9e-10 38.5 1.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF40793.1 - 2.7e-09 36.7 8.2 4.8e-09 35.9 6.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF40793.1 - 2.5e-08 34.1 8.7 1.5e-07 31.6 8.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF40793.1 - 1.9e-07 31.0 4.6 4.3e-07 29.8 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PXF40793.1 - 1.2e-06 28.3 5.8 1.2e-06 28.3 5.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF40793.1 - 5.3e-06 26.4 2.2 5.3e-06 26.4 2.2 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF40793.1 - 0.00039 20.2 6.6 0.00039 20.2 6.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF40793.1 - 0.0018 17.9 3.0 0.0032 17.1 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PXF40793.1 - 0.002 17.9 5.7 0.0052 16.6 5.6 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF40793.1 - 0.0028 17.7 4.7 0.015 15.4 3.9 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PXF40793.1 - 0.057 13.6 6.1 0.46 10.7 6.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 PXF40793.1 - 0.085 12.5 6.3 0.32 10.7 2.2 2.6 2 0 0 2 2 2 0 P-11 zinc finger PHD PF00628.29 PXF40793.1 - 0.57 10.1 7.3 0.21 11.5 4.4 1.9 2 0 0 2 2 2 0 PHD-finger zf-C3H2C3 PF17122.5 PXF40793.1 - 2.8 8.0 9.2 0.25 11.4 3.4 2.3 2 1 0 2 2 1 0 Zinc-finger RINGv PF12906.7 PXF40793.1 - 5 7.3 10.9 1.1 9.5 6.1 2.4 2 2 0 2 2 2 0 RING-variant domain DUF3446 PF11928.8 PXF40794.1 - 1.2 9.5 12.6 3.8 7.9 7.6 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain FAD_binding_6 PF00970.24 PXF40795.1 - 1.1e-31 109.1 0.0 1.6e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PXF40795.1 - 2.7e-30 105.2 0.0 3.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PXF40795.1 - 6.5e-06 26.4 0.0 0.0043 17.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain TH1 PF04858.13 PXF40796.1 - 1.5e-22 80.0 0.1 1.7e-21 76.5 0.1 2.1 1 1 0 1 1 1 1 TH1 protein TBP-binding PF09247.11 PXF40796.1 - 0.017 15.4 0.4 1.3 9.3 0.2 2.5 2 0 0 2 2 2 0 TATA box-binding protein binding Ribosomal_L37e PF01907.19 PXF40797.1 - 2e-25 88.7 14.2 3.2e-25 88.0 14.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 PXF40797.1 - 0.0077 16.3 1.4 0.0098 16.0 1.4 1.2 1 1 0 1 1 1 1 SelR domain DZR PF12773.7 PXF40797.1 - 0.05 13.6 3.7 0.078 13.0 3.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon CDC24_OB3 PF17244.2 PXF40797.1 - 0.14 11.8 1.3 0.16 11.7 1.3 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Rpr2 PF04032.16 PXF40798.1 - 2e-07 31.2 1.6 2e-07 31.2 1.6 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cu2_monoox_C PF03712.15 PXF40798.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF4674 PF15719.5 PXF40798.1 - 4.7 7.2 10.8 19 5.2 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) FAD_binding_3 PF01494.19 PXF40800.1 - 2.4e-14 53.4 0.2 1.1e-08 34.7 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 PXF40800.1 - 3.9e-08 33.0 0.0 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 PXF40800.1 - 5.9e-07 29.0 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PXF40800.1 - 9.8e-05 22.5 0.1 0.00025 21.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PXF40800.1 - 0.00049 20.6 0.1 0.0019 18.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF40800.1 - 0.00051 19.4 0.0 0.11 11.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF40800.1 - 0.0031 16.3 0.8 1.3 7.6 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 PXF40800.1 - 0.0084 15.7 0.3 4 6.9 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF40800.1 - 0.015 14.4 0.6 0.023 13.8 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 PXF40800.1 - 0.056 12.5 0.2 0.45 9.5 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 PXF40800.1 - 0.085 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GalKase_gal_bdg PF10509.9 PXF40801.1 - 5.4e-15 54.7 0.0 1.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PseudoU_synth_1 PF01416.20 PXF40801.1 - 1.9e-11 44.4 0.0 1e-09 38.8 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase GHMP_kinases_C PF08544.13 PXF40801.1 - 1.2e-09 38.3 0.2 7.3e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PXF40801.1 - 2e-08 34.4 0.9 4.2e-08 33.3 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cons_hypoth95 PF03602.15 PXF40802.1 - 5.3e-33 114.2 0.0 6e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 PXF40802.1 - 3.8e-05 23.3 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PXF40802.1 - 0.004 17.8 0.0 0.0057 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 PXF40802.1 - 0.0097 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 PXF40802.1 - 0.0099 15.5 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N6_N4_Mtase PF01555.18 PXF40802.1 - 0.022 14.5 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 DNA methylase RsmJ PF04378.13 PXF40802.1 - 0.047 12.9 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltrans_SAM PF10672.9 PXF40802.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Trigger_N PF05697.13 PXF40803.1 - 5.3e-12 46.3 1.7 7.2e-12 45.8 1.7 1.1 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) DUF1508 PF07411.12 PXF40803.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) FKBP_C PF00254.28 PXF40806.1 - 3.2e-17 62.6 0.0 6.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 PXF40806.1 - 9.6e-14 50.3 4.8 9.5e-07 28.5 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PXF40806.1 - 1.9e-10 40.1 6.0 8.4e-05 22.2 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PXF40806.1 - 8.2e-07 29.0 2.0 0.018 15.1 0.1 2.8 2 1 1 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 PXF40806.1 - 6.4e-06 25.8 2.8 0.0059 16.3 0.0 3.4 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 PXF40806.1 - 7e-06 26.1 2.3 0.0086 16.4 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF40806.1 - 1.2e-05 25.4 2.8 7.6e-05 22.9 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PXF40806.1 - 2.5e-05 24.1 1.9 0.23 11.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF40806.1 - 3.4e-05 23.9 0.4 6.6e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 PXF40806.1 - 6.1e-05 23.4 2.8 0.063 13.9 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF40806.1 - 0.00027 21.4 1.3 0.00058 20.3 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF40806.1 - 0.00038 21.0 0.4 0.0063 17.1 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF40806.1 - 0.002 18.8 0.7 0.021 15.6 0.3 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF40806.1 - 0.0096 16.2 1.3 0.0096 16.2 1.3 1.9 2 1 0 2 2 1 1 Tetratricopeptide repeat MIT PF04212.18 PXF40806.1 - 0.04 14.0 0.5 0.74 9.9 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 PXF40806.1 - 0.17 12.0 1.7 15 5.9 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PXF40806.1 - 2.9 7.9 4.4 20 5.2 0.9 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugarporin_N PF11471.8 PXF40807.1 - 0.0089 16.0 4.1 0.042 13.8 3.3 2.2 1 1 1 2 2 2 1 Maltoporin periplasmic N-terminal extension Hemagglutinin PF00509.18 PXF40807.1 - 0.028 12.9 0.2 0.037 12.4 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin ABC_tran_CTD PF16326.5 PXF40807.1 - 0.1 12.9 3.1 0.22 11.8 3.1 1.5 1 1 0 1 1 1 0 ABC transporter C-terminal domain XhlA PF10779.9 PXF40807.1 - 0.85 9.9 3.5 3.2 8.0 3.5 1.9 1 1 0 1 1 1 0 Haemolysin XhlA SNase PF00565.17 PXF40808.1 - 5.9e-23 81.4 0.2 9.4e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4333 PF14230.6 PXF40808.1 - 0.016 15.5 1.3 0.039 14.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4333) Thioredoxin PF00085.20 PXF40809.1 - 3.4e-08 33.4 0.0 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 PXF40809.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF40809.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 PXF40809.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 PXF40809.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Pkinase PF00069.25 PXF40810.1 - 7.9e-55 186.1 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40810.1 - 3.9e-24 85.3 0.0 5.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF40810.1 - 0.00035 20.0 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PXF40810.1 - 0.0034 17.3 0.1 0.026 14.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DHDPS PF00701.22 PXF40812.1 - 1.1e-94 316.4 0.0 1.3e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2868 PF11067.8 PXF40812.1 - 0.097 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) FHA PF00498.26 PXF40813.1 - 1.4e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Myb_DNA-binding PF00249.31 PXF40813.1 - 0.042 14.1 6.9 5.3 7.3 0.0 4.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain CHDCT2 PF08074.11 PXF40813.1 - 9.2 6.4 7.2 1.1 9.4 1.3 2.6 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain SMC_N PF02463.19 PXF40814.1 - 9.5e-76 254.1 0.2 1.8e-75 253.2 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PXF40814.1 - 1.2e-24 86.9 0.1 6.7e-24 84.5 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PXF40814.1 - 2.7e-14 53.7 1.7 5e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PXF40814.1 - 9e-08 32.2 22.7 9e-08 32.2 22.7 3.8 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 PXF40814.1 - 7e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IFT57 PF10498.9 PXF40814.1 - 0.00041 19.4 15.9 0.00041 19.4 15.9 5.9 2 2 2 5 5 4 2 Intra-flagellar transport protein 57 DUF2353 PF09789.9 PXF40814.1 - 0.00064 19.2 11.5 0.00064 19.2 11.5 6.3 4 2 0 5 5 4 2 Uncharacterized coiled-coil protein (DUF2353) Laminin_II PF06009.12 PXF40814.1 - 0.0057 16.7 67.5 0.22 11.5 11.4 9.0 3 3 5 8 8 8 6 Laminin Domain II ABC_tran PF00005.27 PXF40814.1 - 0.52 10.8 0.0 0.52 10.8 0.0 6.5 3 2 2 5 5 4 0 ABC transporter AAA_23 PF13476.6 PXF40814.1 - 2.4 8.6 88.8 6.2 7.3 49.5 6.3 2 2 1 4 4 3 0 AAA domain Sec8_exocyst PF04048.14 PXF40814.1 - 5.1 7.0 38.2 0.82 9.5 0.4 7.1 6 1 1 7 7 7 0 Sec8 exocyst complex component specific domain Hint PF01079.20 PXF40815.1 - 7e-29 100.9 0.2 1.5e-28 99.8 0.2 1.5 1 1 0 1 1 1 1 Hint module DEC-1_N PF04625.13 PXF40815.1 - 0.043 12.8 1.6 0.061 12.3 1.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Hint PF01079.20 PXF40816.1 - 8.2e-31 107.2 0.7 2.5e-30 105.6 0.7 1.6 1 1 0 1 1 1 1 Hint module Trypsin PF00089.26 PXF40816.1 - 0.015 15.1 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Trypsin MAPEG PF01124.18 PXF40818.1 - 7.4e-16 58.2 0.8 8.8e-16 58.0 0.8 1.1 1 0 0 1 1 1 1 MAPEG family LrgB PF04172.16 PXF40819.1 - 8.1e-38 130.1 22.6 8.1e-38 130.1 22.6 2.2 2 0 0 2 2 2 2 LrgB-like family ATP-synt PF00231.19 PXF40820.1 - 6.2e-63 213.1 0.4 8.1e-63 212.8 0.4 1.1 1 0 0 1 1 1 1 ATP synthase SseB_C PF14581.6 PXF40820.1 - 0.044 13.9 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 SseB protein C-terminal domain TBPIP PF07106.13 PXF40821.1 - 3.4e-19 68.5 0.3 7.3e-19 67.5 0.3 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 PXF40821.1 - 5.4e-07 29.6 0.3 5.4e-07 29.6 0.3 2.2 2 0 0 2 2 1 1 Leucine zipper with capping helix domain Laminin_II PF06009.12 PXF40821.1 - 1.1e-05 25.5 3.0 2.3e-05 24.4 3.0 1.7 1 0 0 1 1 1 1 Laminin Domain II Penicillinase_R PF03965.16 PXF40821.1 - 7.1e-05 23.1 1.2 0.00019 21.8 0.2 2.2 2 1 0 2 2 2 1 Penicillinase repressor DUF948 PF06103.11 PXF40821.1 - 0.0005 20.3 0.3 0.002 18.3 0.5 1.9 2 0 0 2 2 1 1 Bacterial protein of unknown function (DUF948) MarR_2 PF12802.7 PXF40821.1 - 0.0016 18.3 0.0 0.0049 16.7 0.0 1.8 2 0 0 2 2 1 1 MarR family CENP-Q PF13094.6 PXF40821.1 - 0.0018 18.5 8.7 0.0018 18.5 8.7 1.8 2 0 0 2 2 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Lebercilin PF15619.6 PXF40821.1 - 0.0042 16.8 10.5 0.0042 16.8 10.5 1.6 2 0 0 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease HTH_12 PF08461.10 PXF40821.1 - 0.0067 16.4 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain V_ATPase_I PF01496.19 PXF40821.1 - 0.0072 14.3 5.3 0.0081 14.1 5.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FlxA PF14282.6 PXF40821.1 - 0.019 15.0 13.0 0.053 13.5 5.0 2.5 1 1 1 2 2 2 0 FlxA-like protein CENP-F_leu_zip PF10473.9 PXF40821.1 - 0.022 14.8 13.6 0.056 13.5 13.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GPP34 PF05719.11 PXF40821.1 - 0.023 14.7 1.6 0.047 13.7 1.4 1.6 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF2730 PF10805.8 PXF40821.1 - 0.04 14.0 4.3 0.042 13.9 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF5082 PF16888.5 PXF40821.1 - 0.051 13.8 8.9 0.38 11.0 8.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HTH_IclR PF09339.10 PXF40821.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF16 PF01519.16 PXF40821.1 - 0.087 13.3 8.6 0.92 10.0 8.4 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Phe_hydrox_dim PF07976.12 PXF40821.1 - 0.091 12.8 0.4 0.2 11.6 0.3 1.8 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain DUF4407 PF14362.6 PXF40821.1 - 0.12 11.7 8.2 0.16 11.3 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 PXF40821.1 - 0.13 10.2 1.3 0.13 10.2 1.3 1.2 1 0 0 1 1 1 0 Prominin LUC7 PF03194.15 PXF40821.1 - 0.14 11.8 5.6 0.18 11.4 5.6 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DUF2802 PF10975.8 PXF40821.1 - 0.15 12.2 6.8 2.7 8.2 0.9 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2802) LPP PF04728.13 PXF40821.1 - 0.17 12.3 3.4 2.6 8.5 3.8 2.8 2 1 0 2 2 1 0 Lipoprotein leucine-zipper DUF4795 PF16043.5 PXF40821.1 - 0.19 11.3 10.6 0.031 13.9 6.7 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4795) DUF4665 PF15679.5 PXF40821.1 - 0.19 12.4 6.5 0.35 11.5 3.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Cep57_MT_bd PF06657.13 PXF40821.1 - 0.26 11.8 6.5 0.63 10.5 6.5 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4988 PF16378.5 PXF40821.1 - 0.27 10.9 4.8 2.3 7.8 3.0 2.7 1 1 0 2 2 2 0 Domain of unknown function NPV_P10 PF05531.12 PXF40821.1 - 0.28 11.7 5.6 0.25 11.8 3.6 2.1 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 PXF40821.1 - 0.3 11.5 5.7 0.22 12.0 2.6 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF932 PF06067.11 PXF40821.1 - 0.33 10.7 2.7 0.24 11.1 1.4 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF932) DivIC PF04977.15 PXF40821.1 - 0.45 10.3 7.9 0.21 11.4 3.6 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 PXF40821.1 - 0.46 10.5 3.4 0.88 9.6 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 PXF40821.1 - 0.56 9.2 8.7 0.84 8.7 8.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 PXF40821.1 - 0.6 10.5 11.2 0.2 12.0 1.7 2.8 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2205 PF10224.9 PXF40821.1 - 0.61 10.1 7.4 0.16 12.0 2.8 2.3 1 1 2 3 3 3 0 Short coiled-coil protein FapA PF03961.13 PXF40821.1 - 0.8 8.2 15.0 2 6.9 8.6 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 PXF40821.1 - 0.87 8.8 7.5 0.4 9.9 5.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 PXF40821.1 - 0.87 9.5 6.3 2.2 8.2 5.2 2.0 1 1 1 2 2 2 0 Sec34-like family YabA PF06156.13 PXF40821.1 - 1.1 9.9 9.3 1.4 9.6 7.7 1.9 1 1 1 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 PXF40821.1 - 1.3 9.7 5.4 14 6.4 5.4 2.4 1 1 0 1 1 1 0 SlyX FAM76 PF16046.5 PXF40821.1 - 1.4 8.2 8.2 1.8 7.9 8.2 1.3 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 PXF40821.1 - 1.6 9.3 18.2 1 9.9 16.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 PXF40821.1 - 1.8 7.8 4.8 4.2 6.6 4.6 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.11 PXF40821.1 - 2 9.0 9.5 38 4.9 9.2 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DNA_repr_REX1B PF14966.6 PXF40821.1 - 4 8.2 9.1 13 6.5 4.2 2.8 3 1 0 3 3 2 0 DNA repair REX1-B AATF-Che1 PF13339.6 PXF40821.1 - 4 8.1 10.9 1.4 9.6 7.4 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor RRP36 PF06102.12 PXF40821.1 - 7.9 6.4 14.8 0.65 9.9 8.9 2.0 1 1 1 2 2 2 0 rRNA biogenesis protein RRP36 Mod_r PF07200.13 PXF40821.1 - 9.1 6.4 18.8 28 4.8 0.2 2.7 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.6 PXF40821.1 - 9.7 6.7 11.0 0.52 10.8 0.6 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Aminotran_5 PF00266.19 PXF40822.1 - 2.6e-17 62.8 0.0 4.9e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 PXF40822.1 - 2.2e-13 50.1 0.0 7.1e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 PXF40822.1 - 2.1e-05 24.6 0.2 4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 MOSC domain Glyco_transf_15 PF01793.16 PXF40823.1 - 1.1e-05 24.9 0.0 4.5e-05 22.9 0.1 1.9 2 1 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase V-ATPase_G PF03179.15 PXF40825.1 - 2.2e-24 86.0 13.5 2.6e-24 85.8 13.5 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 PXF40825.1 - 0.014 14.8 11.3 0.014 14.8 11.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) V-ATPase_G_2 PF16999.5 PXF40825.1 - 5.6 7.4 18.8 7.1 7.1 18.8 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CitMHS PF03600.16 PXF40826.1 - 2.5e-34 118.8 50.8 1.4e-20 73.7 29.5 2.8 1 1 2 3 3 3 2 Citrate transporter TrkA_C PF02080.21 PXF40826.1 - 5.9e-20 70.9 0.2 1.7e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 TrkA-C domain Na_sulph_symp PF00939.19 PXF40826.1 - 1.4e-09 37.6 38.7 1.5e-05 24.3 8.0 3.9 2 2 2 4 4 4 4 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PXF40827.1 - 4.9e-30 104.8 52.5 1.6e-19 70.2 27.8 2.8 1 1 0 2 2 2 2 Citrate transporter TrkA_C PF02080.21 PXF40827.1 - 6.1e-18 64.4 0.7 1.7e-08 34.2 0.1 2.5 2 0 0 2 2 2 2 TrkA-C domain Pkinase PF00069.25 PXF40828.1 - 1.2e-30 106.8 0.0 1.5e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40828.1 - 2.2e-16 59.9 0.0 2.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF676 PF05057.14 PXF40829.1 - 1.8e-22 80.0 0.1 2.5e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PXF40829.1 - 0.00074 19.4 0.1 0.001 18.9 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PXF40829.1 - 0.00074 19.2 0.3 0.0014 18.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PXF40829.1 - 0.048 13.5 0.1 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PXF40829.1 - 0.069 13.7 0.2 0.11 13.1 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PXF40829.1 - 0.097 12.4 0.1 2.4 7.8 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein DUF2974 PF11187.8 PXF40829.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Acetyltransf_10 PF13673.7 PXF40831.1 - 1.2e-05 25.3 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF40831.1 - 0.00029 21.0 0.0 0.00059 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF40831.1 - 0.00041 20.7 0.0 0.00073 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Spond_N PF06468.13 PXF40832.1 - 3e-10 40.6 0.0 3.2e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Spondin_N DDE_Tnp_4 PF13359.6 PXF40833.1 - 7.4e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease COX5A PF02284.16 PXF40833.1 - 0.096 12.7 0.0 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va DUF563 PF04577.14 PXF40835.1 - 6e-17 62.5 0.0 1.6e-16 61.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Nop52 PF05997.12 PXF40835.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleolar protein,Nop52 DUF563 PF04577.14 PXF40838.1 - 5.8e-16 59.3 0.0 1.1e-15 58.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LapA_dom PF06305.11 PXF40838.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RNase_HII PF01351.18 PXF40840.1 - 5.7e-50 169.9 0.0 3.3e-48 164.1 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease HII Gcw_chp PF09694.10 PXF40840.1 - 0.053 13.5 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Metallophos_2 PF12850.7 PXF40841.1 - 1.2e-09 38.6 0.1 4.4e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PXF40841.1 - 2.3e-08 34.8 0.4 3.6e-08 34.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 PXF40841.1 - 0.0083 15.5 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily adh_short PF00106.25 PXF40842.1 - 2e-48 164.5 0.0 2.5e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF40842.1 - 1.1e-26 93.8 0.0 1.6e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF40842.1 - 3.3e-12 46.7 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF40842.1 - 7.8e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PXF40842.1 - 7.7e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF40842.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PXF40842.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 PXF40842.1 - 0.017 15.5 0.0 0.04 14.4 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.15 PXF40842.1 - 0.027 14.3 0.4 0.12 12.2 0.4 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 PXF40842.1 - 0.037 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 PXF40842.1 - 0.092 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 PXF40842.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 PXF40842.1 - 0.18 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Hep_59 PF07052.11 PXF40843.1 - 1.9e-10 41.5 2.1 1.9e-10 41.5 2.1 3.4 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 TRAPP PF04051.16 PXF40844.1 - 3.7e-35 120.8 0.0 4.1e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF1295 PF06966.12 PXF40846.1 - 4.2e-75 252.3 6.3 5e-75 252.0 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PXF40846.1 - 0.048 14.1 0.0 0.18 12.2 0.0 2.2 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 PXF40846.1 - 0.07 13.1 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2142 PF09913.9 PXF40846.1 - 0.27 10.1 7.0 0.46 9.3 7.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) IBN_N PF03810.19 PXF40848.1 - 7.1e-11 41.9 1.3 2.6e-10 40.1 0.3 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain MTS PF05175.14 PXF40849.1 - 2.4e-12 46.7 0.0 4.3e-11 42.7 0.0 2.6 2 1 0 3 3 3 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PXF40849.1 - 1.1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF40849.1 - 4.3e-07 30.6 0.0 1e-06 29.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF40849.1 - 1.7e-06 27.8 0.0 0.00025 20.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 PXF40849.1 - 7.7e-05 22.2 0.0 0.00058 19.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 PXF40849.1 - 0.00016 22.3 0.0 0.00035 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 PXF40849.1 - 0.002 18.4 0.0 0.0041 17.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) PrmA PF06325.13 PXF40849.1 - 0.0036 16.7 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PXF40849.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PXF40849.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF40849.1 - 0.012 16.3 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PXF40849.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Eco57I PF07669.11 PXF40849.1 - 0.046 14.2 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_15 PF09445.10 PXF40849.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 PXF40849.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 PXF40849.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3052 PF11253.8 PXF40849.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) UFD1 PF03152.14 PXF40850.1 - 1.2e-73 246.2 0.0 1.5e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 polyprenyl_synt PF00348.17 PXF40851.1 - 1.1e-61 208.1 0.0 1.4e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Myb_DNA-binding PF00249.31 PXF40852.1 - 8.7e-09 35.4 0.1 1.8e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF40852.1 - 0.011 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF40852.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Oxysterol_BP PF01237.18 PXF40854.1 - 3.1e-32 111.8 0.3 8e-29 100.6 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein CCDC-167 PF15188.6 PXF40854.1 - 0.25 11.7 4.1 0.46 10.9 4.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Homoserine_dh PF00742.19 PXF40855.1 - 3.9e-51 173.4 0.0 8.2e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.28 PXF40855.1 - 1.1e-50 172.6 0.0 1.6e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.16 PXF40855.1 - 6.7e-20 71.9 0.0 2.1e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 PXF40855.1 - 1.3e-12 47.2 0.9 6.7e-06 25.8 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 PXF40855.1 - 2.8e-12 46.3 2.8 1.1e-05 25.2 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 PXF40855.1 - 0.032 14.2 0.3 0.59 10.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain DEC-1_N PF04625.13 PXF40855.1 - 0.25 10.3 2.3 0.49 9.3 2.3 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CRAL_TRIO PF00650.20 PXF40857.1 - 3.3e-22 78.9 0.0 8.2e-22 77.6 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PXF40857.1 - 8.8e-06 25.9 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPR_16 PF13432.6 PXF40857.1 - 0.19 12.4 0.6 0.41 11.3 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_6 PF08030.12 PXF40859.1 - 0.00084 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF40859.1 - 0.0083 16.2 8.9 0.023 14.8 8.4 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component DUF1398 PF07166.11 PXF40859.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) SAP PF02037.27 PXF40860.1 - 0.085 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 SAP domain Fib_alpha PF08702.10 PXF40862.1 - 0.043 14.0 2.7 0.15 12.3 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2150 PF09920.9 PXF40862.1 - 0.094 12.7 6.3 0.026 14.5 3.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF1199 PF06712.11 PXF40863.1 - 0.15 12.1 2.3 3.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1199) CENP-N PF05238.13 PXF40864.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like zf-C2H2 PF00096.26 PXF40865.1 - 2.2e-12 46.7 7.5 2.3e-06 27.7 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF40865.1 - 5.4e-12 45.6 8.9 3.3e-07 30.4 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF40865.1 - 1.6e-10 40.9 6.1 4.6e-05 23.9 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PXF40865.1 - 3.9e-05 23.5 1.9 3.9e-05 23.5 1.9 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 PXF40865.1 - 7.9e-05 22.9 6.3 0.016 15.6 1.2 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 PXF40865.1 - 0.00037 20.2 6.8 0.032 14.0 2.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 PXF40865.1 - 0.0004 20.1 1.2 0.42 10.4 0.1 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 PXF40865.1 - 0.0085 15.6 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PXF40865.1 - 0.012 15.9 1.3 2.3 8.6 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PXF40865.1 - 0.031 14.6 4.7 0.13 12.6 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PXF40865.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.4 1 1 0 1 1 1 0 GAGA factor zf-C2HE PF16278.5 PXF40865.1 - 0.045 14.2 1.6 0.63 10.5 0.2 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Prok-RING_1 PF14446.6 PXF40865.1 - 0.11 12.4 2.4 5.1 7.1 0.3 2.3 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 PXF40865.1 - 0.24 11.5 2.5 1 9.6 2.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 PXF40865.1 - 1.2 9.2 8.5 2.3 8.2 0.3 2.9 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Spexin PF15171.6 PXF40866.1 - 0.048 13.9 0.9 0.066 13.4 0.6 1.4 1 1 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin DUF3752 PF12572.8 PXF40866.1 - 0.061 13.8 0.4 0.069 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF659 PF04937.15 PXF40868.1 - 1.2e-19 70.7 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 PXF40868.1 - 0.0016 18.2 4.7 0.0054 16.5 1.9 2.8 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region DUF1645 PF07816.11 PXF40868.1 - 1 9.9 6.7 2.5 8.7 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) EXOSC1 PF10447.9 PXF40869.1 - 0.005 17.4 0.4 2.3 8.8 0.1 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 DDE_Tnp_4 PF13359.6 PXF40870.1 - 0.034 13.8 0.0 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease ALIX_LYPXL_bnd PF13949.6 PXF40871.1 - 1.2e-11 44.5 2.5 1.2e-11 44.5 2.5 2.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Borrelia_REV PF03978.13 PXF40871.1 - 0.081 12.9 1.8 1.5 8.8 0.1 2.6 1 1 0 2 2 2 0 Borrelia burgdorferi REV protein Strep_SA_rep PF06696.11 PXF40871.1 - 0.11 12.5 1.4 0.3 11.1 1.4 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Baculo_PEP_C PF04513.12 PXF40871.1 - 0.44 10.6 5.3 3.3 7.8 1.1 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 PXF40871.1 - 0.96 8.5 7.7 0.24 10.5 1.4 2.3 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPMO_10 PF03067.15 PXF40872.1 - 2.8e-15 57.5 0.9 4.4e-15 56.9 0.9 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Big_7 PF17957.1 PXF40872.1 - 0.04 14.7 0.2 0.075 13.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial Ig domain MGTL PF17059.5 PXF40872.1 - 0.11 12.3 1.5 0.36 10.7 1.5 1.8 1 0 0 1 1 1 0 MgtA leader peptide Plant_tran PF04827.14 PXF40873.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein DUF2205 PF10224.9 PXF40875.1 - 0.14 12.2 0.9 0.21 11.6 0.9 1.2 1 0 0 1 1 1 0 Short coiled-coil protein VWA PF00092.28 PXF40879.1 - 1e-17 64.9 0.1 1.5e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF40879.1 - 2.8e-10 40.8 0.1 5.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PXF40879.1 - 8.4e-05 22.1 0.1 0.00022 20.7 0.1 1.6 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 PXF40879.1 - 0.011 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain T3SS_needle_E PF08988.10 PXF40880.1 - 0.097 12.8 2.3 4.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle TIG PF01833.24 PXF40881.1 - 2.4e-23 82.0 35.2 1.5e-08 34.6 2.4 5.3 5 0 0 5 5 5 3 IPT/TIG domain REJ PF02010.15 PXF40881.1 - 1.6e-16 60.2 1.4 5.3e-16 58.4 0.5 2.4 1 1 0 1 1 1 1 REJ domain SPX PF03105.19 PXF40882.1 - 0.084 12.8 11.3 0.1 12.5 11.3 1.3 1 0 0 1 1 1 0 SPX domain PCIF1_WW PF12237.8 PXF40883.1 - 3.2e-08 33.4 0.0 5.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Spermine_synth PF01564.17 PXF40887.1 - 3.2e-36 124.5 0.0 4.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PXF40887.1 - 0.032 14.1 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain RPE65 PF03055.15 PXF40888.1 - 4.4e-17 62.4 0.0 5.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CSN8_PSD8_EIF3K PF10075.9 PXF40889.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Aldedh PF00171.22 PXF40890.1 - 3.1e-07 29.3 0.4 0.0021 16.6 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family GIDA PF01134.22 PXF40892.1 - 5e-11 42.3 0.0 6.1e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A DUF5508 PF17621.2 PXF40892.1 - 0.023 13.9 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5508) DUF4629 PF15442.6 PXF40893.1 - 0.01 16.0 0.8 0.014 15.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) THOC2_N PF16134.5 PXF40893.1 - 0.017 13.8 0.5 0.019 13.6 0.5 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TPR_11 PF13414.6 PXF40894.1 - 1.6e-05 24.5 0.4 0.02 14.6 0.4 3.2 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 PXF40894.1 - 2e-05 24.3 3.3 0.51 10.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF40894.1 - 7.4e-05 22.4 3.7 0.021 14.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF40894.1 - 0.031 14.9 0.4 29 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF40894.1 - 0.058 13.9 0.7 17 6.0 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SNARE PF05739.19 PXF40894.1 - 0.078 13.0 6.0 0.66 10.0 0.4 2.7 3 0 0 3 3 3 0 SNARE domain W_rich_C PF07483.11 PXF40894.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain NICE-3 PF07406.11 PXF40894.1 - 0.12 12.4 1.5 0.19 11.7 1.4 1.4 1 1 0 1 1 1 0 NICE-3 protein K-box PF01486.17 PXF40894.1 - 0.17 12.1 5.0 0.52 10.5 4.9 1.9 1 1 1 2 2 2 0 K-box region Lipase_GDSL_2 PF13472.6 PXF40895.1 - 1.1e-26 94.4 0.0 1.5e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PXF40895.1 - 2.2e-15 57.2 0.0 3.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 PXF40895.1 - 0.19 11.3 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX Diphthamide_syn PF01866.17 PXF40896.1 - 1.1e-109 366.5 0.0 1.4e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SIL1 PF16782.5 PXF40896.1 - 0.04 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 FKBP_C PF00254.28 PXF40897.1 - 3e-20 72.3 0.0 4.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1350 PF07082.11 PXF40898.1 - 1.1e-30 106.8 0.0 2.5e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.7 PXF40898.1 - 0.13 12.9 2.4 0.17 12.4 1.6 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cir_N PF10197.9 PXF40899.1 - 3.4e-11 43.1 13.3 3.4e-11 43.1 13.3 4.5 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 PXF40899.1 - 4.5e-06 27.5 7.8 4.5e-06 27.5 7.8 3.9 2 1 1 3 3 3 1 Pre-mRNA splicing factor Sybindin PF04099.12 PXF40900.1 - 1.7e-30 105.8 0.0 2e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PXF40900.1 - 0.00073 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.27 PXF40901.1 - 2.8e-39 134.7 0.0 3.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PXF40901.1 - 4.6e-29 101.0 0.0 1.5e-28 99.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PXF40901.1 - 7.9e-08 32.6 0.8 2.1e-07 31.2 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF40901.1 - 0.00063 19.8 0.1 0.0019 18.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNase_II_C_S1 PF18614.1 PXF40901.1 - 0.021 14.8 2.1 0.051 13.5 2.1 1.7 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain AAA_29 PF13555.6 PXF40901.1 - 0.083 12.6 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain CAP_GLY PF01302.25 PXF40901.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain PAM2 PF07145.15 PXF40901.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region DUF773 PF05600.12 PXF40902.1 - 7.1e-84 282.4 11.0 8.1e-84 282.2 11.0 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 PROCN PF08083.11 PXF40902.1 - 0.013 14.3 0.1 0.025 13.3 0.1 1.4 1 0 0 1 1 1 0 PROCN (NUC071) domain DUF285 PF03382.14 PXF40902.1 - 0.016 14.9 0.3 0.61 9.8 0.0 2.6 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 ATP-synt_ab PF00006.25 PXF40902.1 - 0.084 12.5 0.4 0.19 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FAM86 PF14904.6 PXF40902.1 - 0.88 9.7 3.3 1.4 9.0 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function Filament PF00038.21 PXF40902.1 - 8.9 5.8 17.1 1.9 8.0 6.9 2.6 2 1 1 3 3 3 0 Intermediate filament protein QueF PF14489.6 PXF40903.1 - 3e-32 110.6 0.0 4.3e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 PXF40903.1 - 0.00072 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term MFMR PF07777.11 PXF40903.1 - 0.021 15.3 0.6 0.12 12.9 0.2 1.9 2 0 0 2 2 2 0 G-box binding protein MFMR SAP30_Sin3_bdg PF13867.6 PXF40904.1 - 1.1e-12 48.1 0.2 1.6e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Creatinase_N_2 PF16189.5 PXF40905.1 - 2e-54 184.0 0.3 5.2e-52 176.2 0.2 2.9 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 PXF40905.1 - 5.6e-43 147.1 0.1 9.4e-43 146.3 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 PXF40905.1 - 6.3e-20 71.0 0.0 2.1e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PXF40905.1 - 1.9e-17 64.1 0.1 1.5e-14 54.8 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mersacidin PF16934.5 PXF40906.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) 5_nucleotid_C PF02872.18 PXF40907.1 - 1.8e-32 112.7 0.0 3.2e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PXF40907.1 - 3.8e-09 37.3 0.0 5.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF40907.1 - 0.0052 17.0 0.0 0.26 11.5 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.27 PXF40908.1 - 2.1e-14 52.9 14.8 2.1e-09 36.9 1.9 3.7 3 0 0 3 3 3 3 SAP domain Yop-YscD_cpl PF16697.5 PXF40908.1 - 9.4e-06 25.9 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HeH PF12949.7 PXF40908.1 - 7.4e-05 22.4 10.8 0.0027 17.4 0.3 3.6 3 0 0 3 3 3 2 HeH/LEM domain Rho_N PF07498.12 PXF40908.1 - 0.006 16.5 1.2 0.017 15.1 1.2 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain FHA PF00498.26 PXF40908.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 FHA domain Viral_cys_rich PF08008.12 PXF40908.1 - 0.17 12.0 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Viral cysteine rich DIMCO_N PF16844.5 PXF40908.1 - 1 9.8 3.5 1.2 9.6 0.1 2.7 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal SRP68 PF16969.5 PXF40910.1 - 4.5e-105 352.8 18.8 1.4e-104 351.2 18.8 1.8 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 PXF40910.1 - 4.4 8.2 6.9 40 5.1 0.8 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF40910.1 - 5 7.5 9.6 20 5.6 2.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 PXF40911.1 - 0.0021 18.1 0.2 0.0088 16.2 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Pinin_SDK_memA PF04696.13 PXF40911.1 - 0.0025 17.9 3.4 0.0025 17.9 3.4 2.4 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 PXF40911.1 - 2.2 7.5 10.4 2.6 7.3 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 PXF40911.1 - 3 6.7 9.0 5.5 5.8 0.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Lipase_3 PF01764.25 PXF40912.1 - 7.6e-30 103.6 0.0 2.1e-29 102.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PXF40912.1 - 0.00044 19.9 0.2 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 PXF40912.1 - 0.0046 17.1 0.1 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 PXF40912.1 - 0.061 13.9 1.5 0.51 10.9 0.0 2.7 2 1 1 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PXF40912.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RCC1 PF00415.18 PXF40913.1 - 4.2e-37 126.5 13.1 2.7e-08 34.3 0.3 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF40913.1 - 1.1e-22 79.3 28.5 1.3e-06 28.0 1.9 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat CAS_C PF12026.8 PXF40913.1 - 0.042 13.9 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain zf-met PF12874.7 PXF40914.1 - 6.3e-05 23.2 0.7 0.00015 22.0 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF40914.1 - 0.0012 19.0 1.1 0.0012 19.0 1.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF40914.1 - 0.0019 18.5 0.5 0.0037 17.6 0.5 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 PXF40914.1 - 0.1 12.5 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger NinG PF05766.12 PXF40914.1 - 4.2 7.3 14.6 7.9 6.4 4.3 2.3 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein TAFII28 PF04719.14 PXF40915.1 - 7.6e-25 86.8 0.5 1.4e-24 85.9 0.1 1.6 2 0 0 2 2 2 1 hTAFII28-like protein conserved region CLCA PF08434.11 PXF40915.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal RNase_Zc3h12a PF11977.8 PXF40916.1 - 3e-09 36.8 0.0 8.6e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain SPX PF03105.19 PXF40916.1 - 0.00078 19.5 3.7 0.00078 19.5 3.7 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 PXF40916.1 - 0.015 14.2 7.6 0.017 14.0 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF908 PF06012.12 PXF40916.1 - 0.019 14.4 5.6 0.024 14.1 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PRORP PF16953.5 PXF40916.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-only RNase P CCDC106 PF15794.5 PXF40916.1 - 0.27 10.9 11.6 0.39 10.4 11.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Zn_Tnp_IS1595 PF12760.7 PXF40916.1 - 0.34 10.9 7.4 0.62 10.1 7.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain SOG2 PF10428.9 PXF40916.1 - 0.42 9.8 18.0 0.55 9.4 18.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_RNApol_7kD PF03604.13 PXF40916.1 - 0.61 9.8 6.2 1.3 8.8 6.2 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Presenilin PF01080.17 PXF40916.1 - 0.67 8.6 4.9 0.8 8.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin Pacs-1 PF10254.9 PXF40916.1 - 0.78 8.6 4.0 1 8.3 4.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein zinc_ribbon_10 PF10058.9 PXF40916.1 - 0.91 9.3 3.9 1.9 8.3 3.9 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Lin-8 PF03353.15 PXF40916.1 - 1.2 8.7 5.4 1.6 8.2 5.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 PXF40916.1 - 1.2 8.3 4.3 1.3 8.2 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MAP65_ASE1 PF03999.12 PXF40916.1 - 1.8 7.2 7.8 2 7.0 7.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Hid1 PF12722.7 PXF40916.1 - 2.2 6.3 6.1 2.5 6.1 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 PXF40916.1 - 2.3 6.6 11.7 2.7 6.4 11.7 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 PXF40916.1 - 2.7 7.5 30.0 4 7.0 30.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 PXF40916.1 - 4.1 7.8 11.3 6.2 7.3 11.3 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) FAM199X PF15814.5 PXF40916.1 - 6.2 5.8 16.0 8.9 5.3 16.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X IMUP PF15761.5 PXF40916.1 - 9.5 7.0 30.4 17 6.1 30.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein GREB1 PF15782.5 PXF40916.1 - 9.7 3.2 10.6 11 2.9 10.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MCM PF00493.23 PXF40917.1 - 1.2e-101 338.5 0.0 1.8e-101 338.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PXF40917.1 - 2.8e-36 124.1 0.1 4.9e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF40917.1 - 2.5e-24 85.5 0.7 7.3e-24 84.0 0.7 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 PXF40917.1 - 6.7e-16 58.9 10.6 6.7e-16 58.9 10.6 2.6 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 PXF40917.1 - 7.4e-16 58.6 1.3 3.2e-15 56.6 0.2 2.6 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 PXF40917.1 - 2.5e-07 30.3 0.0 1.3e-05 24.7 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PXF40917.1 - 4.3e-06 26.8 0.0 1.4e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PXF40917.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PXF40917.1 - 0.044 14.2 0.0 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PXF40917.1 - 0.16 11.6 0.1 23 4.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain tRNA-synt_1c PF00749.21 PXF40918.1 - 7e-112 373.4 0.0 1.4e-111 372.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PXF40918.1 - 5.3e-44 150.1 0.1 2.2e-43 148.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 PXF40918.1 - 1.6e-23 83.5 0.1 3.2e-22 79.3 0.1 2.3 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 PXF40918.1 - 7e-05 23.7 0.4 0.0002 22.2 0.4 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PPR_2 PF13041.6 PXF40918.1 - 0.11 12.7 0.1 34 4.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat family eIF3_subunit PF08597.10 PXF40919.1 - 4.5e-33 115.2 18.9 6.4e-33 114.7 18.9 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit TMEM215 PF15746.5 PXF40919.1 - 0.24 10.8 0.9 0.41 10.1 0.9 1.3 1 0 0 1 1 1 0 TMEM215 family Pannexin_like PF12534.8 PXF40919.1 - 1.4 7.9 3.8 18 4.3 3.4 2.0 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Pkinase PF00069.25 PXF40921.1 - 1.9e-52 178.2 0.0 2.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF40921.1 - 5.2e-23 81.7 0.0 7.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF40921.1 - 0.00014 21.9 0.5 0.0093 15.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF40921.1 - 0.014 14.7 0.4 0.022 14.1 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 PXF40921.1 - 0.032 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 PXF40921.1 - 0.042 12.6 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 PXF40921.1 - 0.12 12.0 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinesin PF00225.23 PXF40922.1 - 1.3e-102 343.2 0.1 1.3e-102 343.2 0.1 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PXF40922.1 - 1.9e-53 180.4 0.0 1.2e-52 177.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Cas_Csa4 PF09703.10 PXF40922.1 - 0.002 17.5 3.1 0.0044 16.4 3.1 1.5 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa4) WD40_alt PF14077.6 PXF40922.1 - 0.14 12.0 1.5 18 5.3 0.0 3.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif HMMR_N PF15905.5 PXF40922.1 - 0.34 10.3 65.7 0.0086 15.6 24.2 3.7 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ApoO PF09769.9 PXF40922.1 - 2.4 8.1 10.5 5.4 7.0 0.2 3.8 2 1 1 3 3 3 0 Apolipoprotein O CENP-F_leu_zip PF10473.9 PXF40922.1 - 5.7 7.0 73.6 0.016 15.3 22.4 4.9 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 PXF40922.1 - 6.2 4.2 62.0 0.43 8.0 31.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) UCH PF00443.29 PXF40923.1 - 5.2e-47 160.5 0.8 8.3e-47 159.8 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF40923.1 - 5.5e-07 29.5 15.2 8.6e-06 25.6 15.2 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PXF40923.1 - 3.1e-06 26.7 5.9 0.074 13.0 0.1 4.3 2 1 1 3 3 3 2 Ubiquitin interaction motif UBA PF00627.31 PXF40923.1 - 0.071 13.0 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Mito_carr PF00153.27 PXF40924.1 - 1e-51 172.8 6.9 2.9e-19 68.8 0.0 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein PAP1 PF08601.10 PXF40924.1 - 2.1 8.0 5.6 2.8 7.6 5.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 GPHR_N PF12537.8 PXF40924.1 - 4.9 7.3 6.8 0.62 10.2 0.3 2.6 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Palm_thioest PF02089.15 PXF40925.1 - 5.2e-08 33.0 0.0 1.6e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 PXF40925.1 - 4.8e-06 26.5 0.0 8.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 PXF40925.1 - 0.00018 22.2 0.2 0.00028 21.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF40925.1 - 0.00021 20.6 0.0 0.31 10.3 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF40925.1 - 0.00078 19.2 0.0 0.0026 17.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 PXF40925.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 PXF40925.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 PXF40925.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 PXF40925.1 - 0.17 12.0 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain ubiquitin PF00240.23 PXF40926.1 - 1.1e-12 47.5 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 PXF40926.1 - 1.4e-06 28.1 40.4 0.00039 20.3 7.0 5.6 2 2 3 5 5 5 4 STI1 domain UBA PF00627.31 PXF40926.1 - 0.00018 21.3 0.1 0.00018 21.3 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 PXF40926.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 PXF40926.1 - 0.00042 20.4 0.5 0.00092 19.2 0.2 1.8 2 0 0 2 2 2 1 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 PXF40926.1 - 0.0015 18.6 0.0 0.0066 16.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GET2 PF08690.10 PXF40926.1 - 0.0022 17.7 0.5 0.0022 17.7 0.5 3.6 3 1 1 4 4 4 1 GET complex subunit GET2 CUE PF02845.16 PXF40926.1 - 0.009 15.7 1.2 0.022 14.5 0.1 2.2 2 0 0 2 2 2 1 CUE domain Ubiquitin_2 PF14560.6 PXF40926.1 - 0.011 16.2 0.1 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain BRO1 PF03097.18 PXF40927.1 - 1.8e-39 135.7 1.1 1.8e-39 135.7 1.1 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 PXF40927.1 - 1.1e-25 90.6 15.7 1.1e-25 90.6 15.7 2.2 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV TetR_C_24 PF17932.1 PXF40927.1 - 0.44 10.8 7.8 11 6.3 0.8 3.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Spond_N PF06468.13 PXF40929.1 - 3.5e-14 53.4 0.0 4e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Hint PF01079.20 PXF40930.1 - 1.3e-26 93.5 0.0 2.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 PXF40930.1 - 0.00059 20.2 0.0 0.0019 18.5 0.0 2.1 1 1 0 1 1 1 1 Hint domain Vint PF14623.6 PXF40930.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Intein_splicing PF14890.6 PXF40930.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Intein splicing domain Trypan_PARP PF05887.11 PXF40930.1 - 0.18 11.8 13.1 0.39 10.7 13.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.10 PXF40930.1 - 1.1 8.6 5.5 1.6 8.0 5.5 1.1 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 PXF40930.1 - 6 6.7 6.5 7.8 6.3 6.5 1.2 1 0 0 1 1 1 0 SPX domain Glyco_transf_20 PF00982.21 PXF40932.1 - 4.9e-152 506.9 0.0 7.7e-152 506.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PXF40932.1 - 4.9e-46 156.7 0.0 1.6e-45 155.1 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 PXF40932.1 - 7.2e-06 25.9 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 PXF40932.1 - 0.15 11.6 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Death_2 PF14786.6 PXF40932.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Tube Death domain UPF0054 PF02130.17 PXF40933.1 - 5.3e-36 123.3 0.0 7.2e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Zincin_1 PF06262.11 PXF40933.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Spc24 PF08286.11 PXF40935.1 - 0.0001 22.5 2.8 0.25 11.6 0.5 2.6 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 GAS PF13851.6 PXF40935.1 - 0.00021 20.7 20.3 0.016 14.6 6.6 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding EMP24_GP25L PF01105.24 PXF40935.1 - 0.0036 17.3 5.0 0.15 12.0 0.8 2.3 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Phage_GPO PF05929.11 PXF40935.1 - 0.028 14.1 0.9 0.028 14.1 0.9 2.2 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF16 PF01519.16 PXF40935.1 - 0.029 14.8 1.3 0.029 14.8 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2730 PF10805.8 PXF40935.1 - 0.034 14.2 5.1 0.3 11.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DivIC PF04977.15 PXF40935.1 - 0.083 12.7 6.5 0.2 11.4 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 PXF40935.1 - 0.14 12.5 0.4 0.14 12.5 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 PXF40935.1 - 0.17 12.3 6.0 5 7.6 0.2 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 PXF40935.1 - 0.18 11.9 5.0 0.37 10.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 PXF40935.1 - 0.23 11.5 15.6 1.6 8.8 4.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 PXF40935.1 - 0.23 11.5 16.9 0.28 11.3 5.1 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ORF6C PF10552.9 PXF40935.1 - 0.24 11.5 4.3 0.65 10.1 1.0 2.6 2 0 0 2 2 2 0 ORF6C domain GrpE PF01025.19 PXF40935.1 - 0.32 10.6 9.2 0.35 10.5 1.5 2.6 2 0 0 2 2 2 0 GrpE Streptin-Immun PF11083.8 PXF40935.1 - 0.51 10.8 4.0 2.8 8.4 0.6 2.9 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein Seryl_tRNA_N PF02403.22 PXF40935.1 - 0.53 10.5 11.2 1.1 9.6 1.3 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 PXF40935.1 - 0.61 10.1 10.4 0.53 10.3 2.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 PXF40935.1 - 4.3 8.1 7.4 3.4 8.4 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CLZ PF16526.5 PXF40935.1 - 4.5 7.7 10.6 0.96 9.9 2.1 3.2 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 PXF40935.1 - 5.4 7.5 16.1 15 6.1 3.0 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Spond_N PF06468.13 PXF40936.1 - 2.7e-22 79.8 0.0 4.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Spondin_N RRM_1 PF00076.22 PXF40936.1 - 1.6e-17 63.1 0.0 2.6e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 PXF40936.1 - 4.5e-12 46.4 1.9 5e-12 46.3 0.4 1.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hydrolase_4 PF12146.8 PXF40937.1 - 5.1e-50 170.0 0.0 4.2e-49 167.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF40937.1 - 6.2e-14 52.3 0.0 4.5e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF40937.1 - 4.1e-08 34.1 0.1 5.1e-08 33.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PXF40937.1 - 6.2e-08 32.4 0.0 0.001 18.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 PXF40937.1 - 2.2e-06 27.5 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 PXF40937.1 - 0.00011 21.9 0.0 0.22 11.1 0.0 2.3 2 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 PXF40937.1 - 0.00056 19.8 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2920 PF11144.8 PXF40937.1 - 0.00059 19.1 0.0 0.0012 18.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_5 PF12695.7 PXF40937.1 - 0.00083 19.2 0.0 0.15 11.8 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PXF40937.1 - 0.00086 19.2 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 PXF40937.1 - 0.0011 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 FSH1 PF03959.13 PXF40937.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 PXF40937.1 - 0.0081 15.7 0.0 0.29 10.7 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.13 PXF40937.1 - 0.0093 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 PXF40937.1 - 0.017 14.9 0.0 0.13 12.1 0.0 2.2 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_8 PF06259.12 PXF40937.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase LIDHydrolase PF10230.9 PXF40937.1 - 0.084 12.4 0.1 0.19 11.3 0.2 1.5 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase LCAT PF02450.15 PXF40937.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HSP70 PF00012.20 PXF40938.1 - 2e-259 861.8 12.0 2.3e-259 861.6 12.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PXF40938.1 - 6.8e-13 48.1 4.4 1.2e-12 47.3 0.0 2.7 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 PXF40938.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain GFO_IDH_MocA PF01408.22 PXF40939.1 - 2.5e-25 89.6 0.1 5.4e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF40939.1 - 8.2e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 PXF40939.1 - 0.0014 19.1 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 PXF40939.1 - 0.0056 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PXF40939.1 - 0.0099 16.1 0.6 0.033 14.5 0.6 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PXF40939.1 - 0.015 15.8 0.0 0.072 13.5 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peripla_BP_1 PF00532.21 PXF40939.1 - 0.066 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family OCD_Mu_crystall PF02423.15 PXF40939.1 - 0.1 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 PXF40939.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF40939.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_10 PF13673.7 PXF40940.1 - 9.9e-11 41.7 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF40940.1 - 5.5e-07 29.9 0.0 8.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF40940.1 - 0.0001 22.5 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 PXF40940.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 PXF40940.1 - 0.046 13.7 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 PXF40940.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 PXF40940.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 PXF40940.1 - 0.097 12.7 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PXF40940.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Lactamase_B PF00753.27 PXF40941.1 - 2.4e-15 57.1 0.9 4.1e-14 53.1 0.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF40941.1 - 0.0056 16.2 0.1 0.0096 15.5 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GETHR PF05671.11 PXF40943.1 - 1.2 8.5 48.2 7.9 6.0 5.5 5.2 1 1 4 5 5 5 0 GETHR pentapeptide repeat (5 copies) Thioredoxin PF00085.20 PXF40944.1 - 1.2e-06 28.5 0.1 2.4e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 PXF40944.1 - 7.8e-05 22.7 0.3 0.014 15.3 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 PXF40945.1 - 9.4e-54 179.7 3.2 2.7e-31 107.6 0.1 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 PXF40945.1 - 3.3e-31 108.6 7.4 1.5e-18 67.4 0.2 3.7 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PXF40945.1 - 1.1e-09 38.7 4.8 7.5e-05 23.1 0.1 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF40945.1 - 4.8e-09 36.3 0.4 0.0044 17.2 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 PXF40945.1 - 1.6e-08 34.3 0.5 0.00056 19.3 0.1 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF40945.1 - 7e-07 29.5 0.5 0.53 10.7 0.0 4.5 4 1 1 5 5 5 3 Thioredoxin-like Thioredoxin_3 PF13192.6 PXF40945.1 - 3.9e-06 26.8 0.7 0.00069 19.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin domain ERp29_N PF07912.13 PXF40945.1 - 2.6e-05 24.4 0.2 0.049 13.8 0.1 2.9 2 0 0 2 2 2 2 ERp29, N-terminal domain AhpC-TSA PF00578.21 PXF40945.1 - 9.2e-05 22.4 0.5 0.17 11.8 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Glutaredoxin PF00462.24 PXF40945.1 - 0.0031 17.7 0.1 1.1 9.6 0.0 2.9 2 0 0 2 2 2 1 Glutaredoxin DIM1 PF02966.16 PXF40945.1 - 0.0086 15.9 0.4 0.88 9.4 0.0 2.8 2 1 1 3 3 3 1 Mitosis protein DIM1 HyaE PF07449.11 PXF40945.1 - 0.02 14.9 0.2 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 PXF40945.1 - 0.059 13.1 0.1 9.1 6.0 0.0 2.6 2 0 0 2 2 2 0 Redoxin TraF PF13728.6 PXF40945.1 - 0.11 12.3 0.1 0.81 9.5 0.0 2.3 3 0 0 3 3 3 0 F plasmid transfer operon protein UBD PF16455.5 PXF40946.1 - 6.2e-20 71.4 0.0 8.9e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain FG-GAP PF01839.23 PXF40947.1 - 0.0019 18.3 0.3 0.0019 18.3 0.3 2.0 2 0 0 2 2 2 1 FG-GAP repeat VCBS PF13517.6 PXF40947.1 - 0.009 16.6 0.4 0.031 14.9 0.4 2.0 1 1 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3140 PF11338.8 PXF40947.1 - 0.12 12.8 0.2 7.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Rpp20 PF12328.8 PXF40949.1 - 9.4e-08 32.1 0.0 0.0011 19.0 0.0 2.4 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 PXF40949.1 - 7.2e-06 25.7 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alba SR-25 PF10500.9 PXF40950.1 - 0.019 14.6 13.0 0.021 14.4 13.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 PXF40950.1 - 7.9 4.9 8.8 7.9 4.9 8.8 1.0 1 0 0 1 1 1 0 Macoilin family ECH_1 PF00378.20 PXF40951.1 - 5.1e-75 252.0 1.5 5.8e-75 251.8 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PXF40951.1 - 6.4e-36 124.5 1.0 9.2e-34 117.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 PXF40951.1 - 0.0038 16.3 0.3 0.0073 15.3 0.1 1.6 2 0 0 2 2 2 1 Serine dehydrogenase proteinase Peptidase_S49 PF01343.18 PXF40951.1 - 0.021 14.8 1.3 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 WXG100 PF06013.12 PXF40952.1 - 0.0082 16.4 0.1 0.07 13.4 0.0 2.2 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF40952.1 - 0.032 14.3 0.2 0.06 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF40952.1 - 0.41 11.3 4.1 0.73 10.5 3.9 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain NADH_B2 PF14813.6 PXF40953.1 - 0.0017 18.1 0.5 0.0022 17.8 0.5 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 CpeT PF06206.11 PXF40954.1 - 1.8e-47 161.7 0.0 2.3e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) F-box PF00646.33 PXF40955.1 - 7.6e-05 22.5 0.2 0.00015 21.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF40955.1 - 0.00033 20.5 0.3 0.00072 19.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 PXF40955.1 - 0.0098 16.2 0.0 1.2 9.5 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BBS1 PF14779.6 PXF40955.1 - 0.037 13.5 0.2 0.4 10.1 0.4 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 PQQ_3 PF13570.6 PXF40955.1 - 0.044 14.3 0.9 10 6.8 0.0 3.2 2 1 0 2 2 2 0 PQQ-like domain Myb_DNA-binding PF00249.31 PXF40956.1 - 2.7e-29 101.1 0.8 8.3e-14 51.5 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF40956.1 - 1e-20 73.8 0.1 4.3e-13 49.3 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF40956.1 - 0.0056 16.6 0.0 0.051 13.5 0.0 2.4 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 PXF40956.1 - 0.0062 16.5 0.0 6.6 6.8 0.0 3.0 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 PXF40956.1 - 0.012 15.7 0.2 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AC_N PF16214.5 PXF40956.1 - 2.6 7.1 5.8 4.1 6.4 5.8 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3138 PF11336.8 PXF40956.1 - 3.1 6.3 9.3 4.7 5.7 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PsbQ PF05757.11 PXF40956.1 - 3.1 7.5 13.2 0.85 9.3 8.6 2.2 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) Ribosomal_60s PF00428.19 PXF40956.1 - 6.1 7.5 18.4 0.59 10.8 13.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF72 PF01904.18 PXF40957.1 - 2.9e-39 135.4 2.6 3.6e-39 135.1 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF72 Consortin_C PF15281.6 PXF40959.1 - 0.072 13.1 1.2 0.1 12.6 1.2 1.3 1 0 0 1 1 1 0 Consortin C-terminus RAMP4 PF06624.12 PXF40959.1 - 7.6 6.7 6.9 1 9.5 2.4 1.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Sec62 PF03839.16 PXF40959.1 - 7.8 5.9 10.7 9.8 5.6 10.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ribonuclease_3 PF00636.26 PXF40961.1 - 6.9e-47 158.4 0.0 1.6e-22 80.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 PXF40961.1 - 1.3e-32 112.7 0.0 7.7e-17 61.7 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.22 PXF40961.1 - 3.2e-05 23.7 0.0 7.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.26 PXF40961.1 - 0.0015 19.2 0.1 0.0037 17.9 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DEAD PF00270.29 PXF40961.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DAHP_synth_2 PF01474.16 PXF40962.1 - 9.4e-185 614.3 0.0 1.1e-184 614.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family AAA_25 PF13481.6 PXF40963.1 - 1.5e-23 83.4 0.0 2.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PXF40963.1 - 4.7e-11 42.5 0.0 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 PXF40963.1 - 8.4e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.6 PXF40963.1 - 3.1e-06 27.4 0.0 8.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain AAA_16 PF13191.6 PXF40963.1 - 3.9e-06 27.4 0.0 8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Toprim_4 PF13662.6 PXF40963.1 - 5.6e-06 26.7 0.0 2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Toprim domain AAA_22 PF13401.6 PXF40963.1 - 0.0069 16.7 0.1 0.036 14.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PXF40963.1 - 0.009 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PXF40963.1 - 0.012 15.3 0.1 0.048 13.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 PXF40963.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 PXF40963.1 - 0.019 15.5 0.1 0.042 14.4 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Toprim PF01751.22 PXF40963.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Toprim domain AAA_23 PF13476.6 PXF40963.1 - 0.088 13.3 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3991 PF13154.6 PXF40963.1 - 0.11 12.8 0.0 0.48 10.8 0.0 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF3991) cobW PF02492.19 PXF40963.1 - 0.17 11.4 0.6 0.43 10.2 0.3 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 PXF40963.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 PXF40963.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 PXF40963.1 - 0.23 10.6 0.1 0.37 9.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PGK PF00162.19 PXF40964.1 - 2.4e-162 540.2 0.1 2.9e-162 539.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 PXF40964.1 - 0.018 14.6 0.3 0.43 10.1 0.0 2.5 2 1 0 2 2 2 0 Propionate catabolism activator VHL_C PF17211.3 PXF40964.1 - 0.15 12.1 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 VHL box domain LDB19 PF13002.7 PXF40966.1 - 0.066 12.9 0.0 0.066 12.9 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like DAGK_cat PF00781.24 PXF40968.1 - 7.2e-22 77.3 0.5 1.2e-21 76.6 0.5 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 PXF40968.1 - 0.016 14.4 0.2 0.024 13.8 0.2 1.2 1 0 0 1 1 1 0 ATP-NAD kinase PEGA PF08308.11 PXF40968.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 PEGA domain UPF0542 PF15086.6 PXF40968.1 - 4 7.4 4.7 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 NAS PF03059.16 PXF40969.1 - 1.6e-11 44.1 0.1 1.7e-08 34.2 0.0 2.7 2 1 0 2 2 2 2 Nicotianamine synthase protein 3HCDH_N PF02737.18 PXF40969.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 PXF40969.1 - 0.0038 17.9 0.0 0.0098 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Toxin_31 PF08119.11 PXF40969.1 - 0.05 13.4 0.5 0.66 9.8 0.0 2.5 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family Methyltransf_31 PF13847.6 PXF40969.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain C8 PF08742.11 PXF40969.1 - 0.094 13.2 0.1 9.9 6.7 0.0 2.7 3 0 0 3 3 3 0 C8 domain Spermine_synth PF01564.17 PXF40969.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain FKBP_C PF00254.28 PXF40970.1 - 0.028 14.7 0.1 0.068 13.5 0.0 1.7 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C2H2_11 PF16622.5 PXF40971.1 - 0.0027 17.4 0.7 0.0027 17.4 0.7 1.5 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 PXF40971.1 - 0.09 13.3 0.3 0.16 12.5 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF40971.1 - 0.15 13.0 0.3 0.27 12.2 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger TTR-52 PF01060.23 PXF40974.1 - 0.00077 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 Transthyretin-like family Nipped-B_C PF12830.7 PXF40976.1 - 0.015 15.3 0.0 0.036 14.0 0.0 1.6 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus HEAT PF02985.22 PXF40976.1 - 0.11 12.8 0.1 7.9 7.0 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat STAG PF08514.11 PXF40977.1 - 1.4e-16 60.4 0.1 2.6e-16 59.5 0.1 1.5 1 1 0 1 1 1 1 STAG domain FAM76 PF16046.5 PXF40977.1 - 0.026 13.9 0.2 0.034 13.5 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein TTR-52 PF01060.23 PXF40981.1 - 3.9e-05 24.3 0.0 8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Transthyretin-like family UCH PF00443.29 PXF40982.1 - 1.4e-42 146.0 0.0 1.8e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF40982.1 - 3.8e-11 43.1 0.0 1.2e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.26 PXF40983.1 - 3.1e-19 68.3 33.9 8.8e-05 22.8 1.9 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF40983.1 - 7.3e-16 57.5 29.0 5.2e-05 23.7 0.2 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF40983.1 - 8.3e-10 38.6 23.8 0.00075 19.8 0.1 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PXF40983.1 - 1.3e-07 31.8 10.4 0.1 12.9 1.8 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PXF40983.1 - 2.7e-06 27.6 12.1 0.00098 19.4 0.1 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PXF40983.1 - 0.00044 20.2 25.5 0.13 12.3 0.5 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PXF40983.1 - 0.001 18.7 3.2 0.047 13.5 0.8 5.2 5 1 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 PXF40983.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 3.9 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-BED PF02892.15 PXF40983.1 - 0.0059 16.6 18.0 0.024 14.6 2.1 4.5 4 2 0 4 4 4 1 BED zinc finger C1_4 PF07975.12 PXF40983.1 - 0.0068 16.6 17.5 2 8.7 4.3 4.3 2 1 2 4 4 4 1 TFIIH C1-like domain zinc_ribbon_15 PF17032.5 PXF40983.1 - 0.014 16.1 14.9 0.98 10.2 4.1 3.3 1 1 2 3 3 3 0 zinc-ribbon family DUF2256 PF10013.9 PXF40983.1 - 0.014 15.5 9.2 0.79 9.9 0.0 3.8 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_2 PF03107.16 PXF40983.1 - 0.018 15.4 22.2 7.7 6.9 0.1 5.3 1 1 3 4 4 4 0 C1 domain zf-met PF12874.7 PXF40983.1 - 0.037 14.4 1.9 0.037 14.4 1.9 4.7 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PXF40983.1 - 0.064 13.6 15.7 4.6 7.6 2.0 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 PXF40983.1 - 0.09 13.5 11.4 5.5 7.7 0.1 3.2 2 2 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 PXF40983.1 - 0.1 12.7 15.9 0.087 12.9 1.2 3.3 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Actin_micro PF17003.5 PXF40983.1 - 0.53 9.4 11.1 1.5 7.9 1.0 3.5 1 1 2 4 4 4 0 Putative actin-like family ADK_lid PF05191.14 PXF40983.1 - 0.55 10.3 9.9 4.8 7.3 0.8 3.7 3 1 0 3 3 3 0 Adenylate kinase, active site lid GAGA PF09237.11 PXF40983.1 - 0.56 10.0 0.1 0.56 10.0 0.1 3.0 2 1 1 3 3 3 0 GAGA factor zf_UBZ PF18439.1 PXF40983.1 - 0.6 9.8 15.2 1.8 8.2 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 PXF40983.1 - 0.64 10.4 15.3 1.3 9.3 7.3 3.0 1 1 2 3 3 3 0 C2H2-type zinc ribbon Trm112p PF03966.16 PXF40983.1 - 1.3 9.6 6.9 7.5 7.2 0.1 3.3 3 1 0 3 3 2 0 Trm112p-like protein zf_C2H2_ZHX PF18387.1 PXF40983.1 - 1.3 8.7 12.0 14 5.4 0.0 3.8 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain FYVE PF01363.21 PXF40983.1 - 1.4 9.1 21.7 0.5 10.5 0.8 3.5 1 1 1 3 3 3 0 FYVE zinc finger zf-AN1 PF01428.16 PXF40983.1 - 3.3 8.0 17.0 12 6.2 0.2 5.0 5 0 0 5 5 5 0 AN1-like Zinc finger PyrI_C PF02748.15 PXF40983.1 - 4.8 7.2 9.1 1.1 9.2 0.4 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 PXF40983.1 - 6 6.9 30.5 0.54 10.2 0.6 5.7 6 1 0 6 6 6 0 zinc-finger of a C2HC-type TF_Zn_Ribbon PF08271.12 PXF40983.1 - 8 6.1 10.7 5.9 6.5 1.7 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding MNNL PF07657.13 PXF40984.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 N terminus of Notch ligand E3_UbLigase_R4 PF13764.6 PXF40988.1 - 4e-25 88.2 0.0 5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 E3_UbLigase_R4 PF13764.6 PXF40989.1 - 1.9e-10 39.6 0.1 2.4e-10 39.3 0.1 1.0 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 LmjF365940-deam PF14421.6 PXF40989.1 - 0.027 14.1 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases ZapB PF06005.12 PXF40991.1 - 0.0021 18.5 1.5 0.0046 17.4 1.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB TMF_DNA_bd PF12329.8 PXF40991.1 - 0.0034 17.3 0.7 0.0096 15.9 0.7 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF2046 PF09755.9 PXF40991.1 - 0.0055 16.0 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Cyclin_C_2 PF16899.5 PXF40991.1 - 0.0061 16.9 0.4 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain NB-ARC PF00931.22 PXF40991.1 - 0.0068 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain JIP_LZII PF16471.5 PXF40991.1 - 0.0078 16.4 0.6 0.016 15.4 0.6 1.5 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 PXF40991.1 - 0.012 15.7 1.0 0.026 14.6 1.0 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-C3HC4_3 PF13920.6 PXF40991.1 - 0.013 15.3 2.5 0.023 14.5 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HALZ PF02183.18 PXF40991.1 - 0.02 15.1 0.8 0.042 14.1 0.6 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4140 PF13600.6 PXF40991.1 - 0.054 13.9 0.8 0.16 12.4 0.8 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 PXF40991.1 - 0.056 13.7 0.6 0.11 12.8 0.6 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 PXF40991.1 - 0.059 13.2 0.5 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 PXF40991.1 - 0.071 13.2 3.9 0.22 11.6 0.9 2.7 2 1 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 PXF40991.1 - 0.072 13.5 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 PXF40991.1 - 0.14 12.5 1.3 0.35 11.2 0.3 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family APC_N_CC PF16689.5 PXF40991.1 - 0.15 12.2 1.2 0.3 11.2 1.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain NB-ARC PF00931.22 PXF40994.1 - 2.4e-09 36.7 0.0 2.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain bZIP_1 PF00170.21 PXF40995.1 - 2.1e-05 24.5 7.9 2.1e-05 24.5 7.9 2.2 1 1 1 2 2 2 1 bZIP transcription factor RepC PF06504.11 PXF40995.1 - 0.0011 18.3 0.3 0.0013 18.0 0.3 1.1 1 0 0 1 1 1 1 Replication protein C (RepC) DUF1617 PF07761.12 PXF40995.1 - 0.044 13.9 2.2 0.047 13.8 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1617) DUF444 PF04285.12 PXF40995.1 - 0.16 11.0 6.8 0.11 11.5 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF444) Uma2 PF05685.12 PXF40996.1 - 0.00022 20.8 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative restriction endonuclease Tropomyosin PF00261.20 PXF40996.1 - 0.0095 15.3 13.0 0.12 11.7 5.7 2.2 1 1 1 2 2 2 2 Tropomyosin DUF4407 PF14362.6 PXF40996.1 - 0.025 13.9 11.3 0.037 13.4 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AbrB-like PF14250.6 PXF40996.1 - 0.064 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Fez1 PF06818.15 PXF40996.1 - 0.49 10.8 8.8 0.84 10.1 8.8 1.3 1 0 0 1 1 1 0 Fez1 Alanine_zipper PF11839.8 PXF40996.1 - 1 9.7 26.4 0.11 12.8 21.8 1.7 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Macoilin PF09726.9 PXF40996.1 - 1.7 7.1 14.4 2.5 6.6 14.4 1.3 1 0 0 1 1 1 0 Macoilin family PEMT PF04191.13 PXF40997.1 - 4.1e-10 40.0 0.0 5.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 PXF40997.1 - 4.3e-05 23.8 0.0 5.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.11 PXF40997.1 - 0.0016 18.0 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.17 PXF40997.1 - 0.0043 15.9 0.0 0.0056 15.5 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 PXF40997.1 - 0.074 13.0 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase LtrA PF06772.11 PXF40997.1 - 0.085 12.1 0.0 0.095 11.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Uso1_p115_head PF04869.14 PXF40997.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region PMM PF03332.13 PXF40998.1 - 6.1e-105 349.9 0.5 7e-105 349.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PXF40998.1 - 1.7e-06 28.0 0.0 5.4e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF40998.1 - 1.8e-05 24.4 0.0 0.0048 16.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase zf-C2H2_10 PF16588.5 PXF41001.1 - 0.03 14.0 12.5 0.09 12.5 0.6 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger CLZ PF16526.5 PXF41001.1 - 0.1 13.0 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-CCHC_4 PF14392.6 PXF41001.1 - 0.14 11.9 7.2 2.3 8.0 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle SRP-alpha_N PF04086.13 PXF41002.1 - 0.0095 15.9 10.0 0.015 15.2 10.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal APAF1_C PF17908.1 PXF41003.1 - 3e-06 27.3 0.0 8.4e-06 25.8 0.0 1.7 1 1 1 2 2 2 1 APAF-1 helical domain SAP PF02037.27 PXF41003.1 - 0.025 14.4 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 SAP domain ABC_tran PF00005.27 PXF41004.1 - 2.4e-05 24.9 0.0 3.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PXA PF02194.15 PXF41006.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 PXA domain Hormone_2 PF00123.20 PXF41006.1 - 0.096 12.6 0.9 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Peptide hormone DUF2090 PF09863.9 PXF41007.1 - 0.00017 20.8 0.0 0.0002 20.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) SBDS PF01172.18 PXF41009.1 - 0.06 13.4 0.8 0.073 13.2 0.8 1.3 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein DDT PF02791.17 PXF41011.1 - 0.00049 20.3 0.1 0.0037 17.5 0.1 2.2 2 0 0 2 2 2 1 DDT domain Methyltransf_5 PF01795.19 PXF41011.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family peroxidase PF00141.23 PXF41012.1 - 4.9e-24 85.3 0.0 7.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.19 PXF41013.1 - 2e-17 63.5 0.0 4.3e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PXF41013.1 - 0.00052 20.2 0.0 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 PXF41013.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 PXF41013.1 - 0.0015 17.8 0.0 0.011 15.0 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF41013.1 - 0.0042 17.6 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF41013.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF41013.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 PXF41013.1 - 0.041 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 PXF41013.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 PXF41013.1 - 0.07 12.2 0.0 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 PXF41013.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4061 PF13270.6 PXF41014.1 - 0.018 15.3 2.9 0.018 15.3 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) gp32 PF08804.10 PXF41014.1 - 0.061 13.4 0.4 0.092 12.8 0.4 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like Pkinase PF00069.25 PXF41016.1 - 8.4e-12 45.0 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF41016.1 - 1.1e-06 28.8 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PXF41016.1 - 6e-06 25.7 0.0 7.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF41016.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF41016.1 - 0.00045 19.9 0.1 0.00091 18.9 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PXF41016.1 - 0.0014 17.5 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF41016.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like QueF PF14489.6 PXF41018.1 - 0.025 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Hva1_TUDOR PF11160.8 PXF41018.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain Geminin PF07412.12 PXF41019.1 - 0.022 14.5 0.1 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Geminin DUF4836 PF16120.5 PXF41020.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4836) CobN-Mg_chel PF02514.16 PXF41023.1 - 2.4e-06 25.7 0.0 2.6e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Plavaka PF18759.1 PXF41024.1 - 0.017 14.4 0.0 0.024 13.8 0.0 1.4 2 0 0 2 2 2 0 Plavaka transposase Transposase_21 PF02992.14 PXF41024.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Transposase family tnp2 DUF1258 PF06869.12 PXF41024.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF4836 PF16120.5 PXF41026.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4836) Geminin PF07412.12 PXF41027.1 - 0.024 14.4 0.1 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Geminin QueF PF14489.6 PXF41028.1 - 0.037 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Hva1_TUDOR PF11160.8 PXF41028.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain MFS_1 PF07690.16 PXF41030.1 - 2.4e-09 36.6 34.5 2.4e-09 36.6 34.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily ELO PF01151.18 PXF41030.1 - 5.9 6.3 12.4 0.17 11.4 4.6 2.2 3 0 0 3 3 3 0 GNS1/SUR4 family Chloroa_b-bind PF00504.21 PXF41032.1 - 0.00015 22.3 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAD_binding_5 PF07994.12 PXF41033.1 - 1.1e-125 419.3 0.0 1.3e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PXF41033.1 - 7.1e-33 113.1 0.4 1.3e-32 112.3 0.4 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Lactamase_B_6 PF16661.5 PXF41034.1 - 8e-22 77.6 0.0 4e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PXF41034.1 - 2e-14 53.6 0.0 3.3e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF41034.1 - 1.5e-13 51.2 0.0 4.3e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Beta-Casp PF10996.8 PXF41034.1 - 2e-09 37.7 0.0 3.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 PXF41034.1 - 2.6e-09 36.9 0.0 5.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 PXF41034.1 - 1.9e-05 24.6 0.0 0.00011 22.2 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Peptidase_S49 PF01343.18 PXF41035.1 - 9.4e-66 220.5 0.1 6.7e-44 149.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 PXF41035.1 - 6.5e-09 35.9 1.7 0.00017 21.5 0.1 3.3 3 0 0 3 3 3 2 Clp protease ECH_1 PF00378.20 PXF41035.1 - 0.00019 20.8 4.4 0.89 8.8 0.1 4.5 4 2 0 4 4 4 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 PXF41035.1 - 0.001 18.2 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase TipAS PF07739.13 PXF41035.1 - 0.33 11.5 4.5 23 5.5 0.5 3.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Acyltransferase PF01553.21 PXF41036.1 - 5.9e-18 64.8 0.0 8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.13 PXF41036.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF374) Mt_ATP-synt_D PF05873.12 PXF41039.1 - 0.076 12.9 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) 2-oxoacid_dh PF00198.23 PXF41044.1 - 7.7e-64 215.3 0.2 9.1e-64 215.1 0.2 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MADF_DNA_bdg PF10545.9 PXF41047.1 - 0.12 12.7 2.3 0.15 12.4 0.2 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TraF_2 PF13729.6 PXF41047.1 - 0.17 11.2 0.5 0.4 10.0 0.1 1.6 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Cu-oxidase_2 PF07731.14 PXF41048.1 - 2.3e-06 27.4 3.0 1.8e-05 24.5 3.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase Lgl_C PF08596.10 PXF41048.1 - 0.033 12.9 0.0 0.037 12.7 0.0 1.0 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal RVT_2 PF07727.14 PXF41049.1 - 0.02 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PWWP PF00855.17 PXF41051.1 - 4.1e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 PWWP domain CCDC154 PF15450.6 PXF41051.1 - 0.0065 15.1 6.1 0.021 13.4 1.0 2.1 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 154 FAM184 PF15665.5 PXF41051.1 - 0.21 11.4 4.4 0.84 9.4 1.3 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3450 PF11932.8 PXF41051.1 - 0.24 10.7 3.8 0.72 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HMMR_C PF15908.5 PXF41051.1 - 1 9.6 8.5 0.14 12.4 0.3 2.9 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal IPK PF03770.16 PXF41052.1 - 7.8e-48 163.0 0.0 1.5e-47 162.1 0.0 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase Trypsin PF00089.26 PXF41054.1 - 2.4e-29 102.8 0.0 2.7e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF41054.1 - 1.3e-06 29.4 0.0 1.8e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain T7SS_ESX_EspC PF10824.8 PXF41056.1 - 0.022 15.2 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Hyphal_reg_CWP PF11765.8 PXF41056.1 - 0.072 12.0 0.2 0.087 11.7 0.2 1.1 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal eIF-5a PF01287.20 PXF41056.1 - 0.097 12.8 0.6 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF2306 PF10067.9 PXF41057.1 - 8.6e-07 29.3 10.3 8.6e-07 29.3 10.3 2.2 2 1 0 2 2 2 1 Predicted membrane protein (DUF2306) Erv26 PF04148.13 PXF41057.1 - 0.012 15.4 0.6 0.035 13.9 0.6 1.7 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Ferric_reduct PF01794.19 PXF41057.1 - 1.4 9.1 13.3 17 5.6 11.6 2.8 1 1 1 2 2 2 0 Ferric reductase like transmembrane component ACT PF01842.25 PXF41059.1 - 3.1e-08 33.2 0.6 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 PXF41059.1 - 1.5e-05 25.5 0.1 0.1 13.2 0.0 2.4 2 0 0 2 2 2 2 ACT domain Peptidase_M32 PF02074.15 PXF41060.1 - 3.1e-172 573.7 0.0 3.5e-172 573.6 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DUF4279 PF14106.6 PXF41060.1 - 0.081 13.1 0.2 0.55 10.4 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Glycos_transf_2 PF00535.26 PXF41061.1 - 3.4e-09 36.7 0.0 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF41061.1 - 1.5e-07 31.5 0.2 4.8e-07 29.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PXF41061.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Laminin_II PF06009.12 PXF41062.1 - 0.047 13.7 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II EzrA PF06160.12 PXF41063.1 - 0.011 13.9 1.2 0.016 13.4 1.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF41063.1 - 0.019 15.2 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF41063.1 - 9.8 6.9 13.8 1.7 9.3 6.8 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Nucleoporin2 PF04096.14 PXF41065.1 - 2.5e-33 115.3 0.0 4.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase 2-Hacid_dh_C PF02826.19 PXF41066.1 - 7.1e-52 175.3 0.2 1.3e-51 174.5 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PXF41066.1 - 1.3e-06 28.1 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PXF41066.1 - 0.00042 20.5 0.3 0.00074 19.7 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PXF41066.1 - 0.022 14.8 0.4 0.053 13.6 0.4 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 PXF41066.1 - 0.042 14.3 0.1 0.085 13.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 PXF41066.1 - 0.046 13.0 2.6 0.13 11.6 2.6 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PXF41066.1 - 0.051 13.5 0.3 0.089 12.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 PXF41066.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 PXF41066.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 PXF41066.1 - 0.24 10.7 0.8 0.49 9.7 0.8 1.5 1 0 0 1 1 1 0 ThiF family Glyco_tran_28_C PF04101.16 PXF41067.1 - 8e-23 81.2 0.0 9.4e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 PXF41067.1 - 0.043 14.2 0.2 0.055 13.9 0.2 1.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 UDPGT PF00201.18 PXF41067.1 - 0.095 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase bZIP_1 PF00170.21 PXF41068.1 - 1.2e-08 34.9 4.6 1.2e-08 34.9 4.6 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF41068.1 - 3.2e-05 23.9 5.4 6.7e-05 22.9 5.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TFIIA PF03153.13 PXF41068.1 - 1.8 8.5 15.1 2.9 7.8 15.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HA2 PF04408.23 PXF41069.1 - 6.3e-21 74.7 0.6 1.8e-20 73.2 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PXF41069.1 - 4.9e-17 62.1 0.0 1.2e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PXF41069.1 - 1.9e-14 53.9 0.0 5.6e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF41069.1 - 4e-07 30.0 1.0 9.1e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 PXF41069.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PXF41069.1 - 0.022 14.8 0.0 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 PXF41069.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 PXF41069.1 - 0.067 13.5 0.0 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 PXF41069.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain GalP_UDP_transf PF01087.22 PXF41070.1 - 5.8e-65 219.2 0.0 8.7e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 PXF41070.1 - 8.6e-60 201.3 0.1 2.9e-59 199.5 0.1 1.7 1 1 1 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Terminase_3 PF04466.13 PXF41070.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit Pept_tRNA_hydro PF01195.19 PXF41071.1 - 8.6e-54 182.1 0.0 1e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase polyprenyl_synt PF00348.17 PXF41072.1 - 9e-71 237.9 0.0 1.1e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 PXF41072.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 GAIN PF16489.5 PXF41072.1 - 0.14 11.5 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain Ndufs5 PF10200.9 PXF41073.1 - 0.00083 19.6 0.1 0.00092 19.4 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.9 PXF41073.1 - 0.0032 17.7 1.3 0.0046 17.2 1.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 PXF41073.1 - 0.009 15.7 1.9 0.013 15.2 1.9 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 PXF41073.1 - 0.035 14.1 4.9 0.057 13.4 4.9 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PXF41073.1 - 0.04 14.1 1.5 0.061 13.5 1.5 1.3 1 0 0 1 1 1 0 CHCH domain COX6B PF02297.17 PXF41073.1 - 0.081 13.2 0.8 0.081 13.2 0.8 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1318 PF07027.12 PXF41073.1 - 0.087 13.3 0.6 0.1 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) Phage_holin_2_4 PF16082.5 PXF41073.1 - 0.3 10.9 1.6 0.45 10.3 1.6 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like UPF0203 PF05254.12 PXF41073.1 - 0.39 11.0 4.6 6.2 7.1 4.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 PXF41073.1 - 0.41 11.0 6.3 2.4 8.6 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PHM7_cyt PF14703.6 PXF41074.1 - 0.029 14.6 1.5 0.13 12.5 0.1 2.4 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter LXG PF04740.12 PXF41074.1 - 0.78 9.4 11.2 0.43 10.3 3.2 3.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Med9 PF07544.13 PXF41074.1 - 7.3 6.8 13.7 0.41 10.8 0.9 4.3 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 ATP_synt_H PF05493.13 PXF41075.1 - 5.4e-20 71.6 1.1 6.3e-20 71.4 1.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF3149 PF11346.8 PXF41075.1 - 0.0033 17.0 1.2 0.063 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3149) Hum_adeno_E3A PF05393.11 PXF41075.1 - 0.0033 17.4 0.1 0.0034 17.3 0.1 1.2 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein DUF5527 PF17665.1 PXF41075.1 - 0.018 14.6 1.1 0.02 14.4 0.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5527) DUF1129 PF06570.11 PXF41075.1 - 0.081 12.4 0.6 0.081 12.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TssN PF17555.2 PXF41075.1 - 0.13 11.6 1.2 0.14 11.5 1.2 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN ABC2_membrane_3 PF12698.7 PXF41075.1 - 0.13 11.3 1.5 0.14 11.2 1.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.6 PXF41075.1 - 0.14 11.8 1.4 0.16 11.6 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3007 PF11460.8 PXF41075.1 - 0.16 12.2 1.1 0.19 12.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) CPP1-like PF11833.8 PXF41075.1 - 0.17 11.5 2.3 0.19 11.4 2.3 1.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 PXF41076.1 - 3.4e-09 37.2 0.4 0.027 15.4 0.2 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41076.1 - 5.8e-05 23.3 0.0 0.004 17.4 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SH3_1 PF00018.28 PXF41077.1 - 0.03 13.9 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 SH3 domain TALPID3 PF15324.6 PXF41077.1 - 1.5 6.4 9.8 1.9 6.1 9.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Neisseria_TspB PF05616.13 PXF41077.1 - 1.5 7.2 5.7 2 6.8 5.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein GSDH PF07995.11 PXF41078.1 - 2.7e-24 86.1 0.0 5.2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 PXF41078.1 - 0.0015 18.4 0.4 0.0095 15.9 0.1 2.5 2 0 0 2 2 2 1 NHL repeat PQQ_3 PF13570.6 PXF41078.1 - 0.043 14.3 0.0 8.1 7.1 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Abhydrolase_1 PF00561.20 PXF41079.1 - 1.1e-23 84.3 0.1 6.3e-21 75.2 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF41079.1 - 1.8e-10 40.5 0.0 5.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF41079.1 - 4e-08 34.1 0.4 5.4e-08 33.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PXF41079.1 - 0.016 14.8 0.0 5 6.6 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3752 PF12572.8 PXF41082.1 - 0.037 14.5 0.1 0.05 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF3819 PF12842.7 PXF41083.1 - 3.4e-38 130.9 0.7 5.7e-38 130.1 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 PXF41084.1 - 3.8e-44 150.1 0.0 5.7e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 PXF41084.1 - 0.15 11.4 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain TrbH PF07283.11 PXF41085.1 - 0.096 12.9 0.1 0.44 10.7 0.1 2.0 2 1 0 2 2 2 0 Conjugal transfer protein TrbH zf-MIZ PF02891.20 PXF41086.1 - 2.5e-13 49.5 0.1 5.5e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PXF41086.1 - 0.0058 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PINIT PF14324.6 PXF41086.1 - 0.0066 16.8 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 PINIT domain Ca_hom_mod PF14798.6 PXF41086.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator zf-C2H2 PF00096.26 PXF41086.1 - 0.067 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PHD PF00628.29 PXF41086.1 - 0.14 12.0 2.6 0.74 9.8 0.5 2.2 2 0 0 2 2 2 0 PHD-finger bMG10 PF17973.1 PXF41088.1 - 0.006 16.8 0.3 0.012 15.8 0.3 1.5 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain bZIP_1 PF00170.21 PXF41088.1 - 2.3 8.4 25.2 0.034 14.3 16.7 2.2 2 0 0 2 2 2 0 bZIP transcription factor LMBR1 PF04791.16 PXF41088.1 - 6.4 5.6 6.8 8.5 5.2 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 PXF41089.1 - 1.6 9.0 3.7 26 5.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Adap_comp_sub PF00928.21 PXF41090.1 - 1.1e-26 93.8 0.0 1.6e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Keratin_2_head PF16208.5 PXF41090.1 - 0.0045 17.1 30.2 0.013 15.7 30.2 1.8 1 0 0 1 1 1 1 Keratin type II head Clat_adaptor_s PF01217.20 PXF41090.1 - 0.0062 16.5 0.1 0.0097 15.8 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TAF4 PF05236.14 PXF41090.1 - 0.034 13.9 3.8 0.056 13.2 3.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MmoB_DmpM PF02406.17 PXF41091.1 - 0.0031 17.7 0.1 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 MmoB/DmpM family Pantoate_ligase PF02569.15 PXF41091.1 - 0.014 14.6 0.3 0.016 14.5 0.3 1.0 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase THOC7 PF05615.13 PXF41091.1 - 0.035 14.4 5.6 0.04 14.2 5.6 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF16 PF01519.16 PXF41091.1 - 0.042 14.3 2.0 0.055 14.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 PXF41091.1 - 0.081 13.0 1.5 0.13 12.3 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 PXF41091.1 - 0.091 13.1 2.3 0.13 12.6 2.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 PXF41091.1 - 0.12 12.6 5.3 0.15 12.3 5.3 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 LtrA PF06772.11 PXF41093.1 - 1.3e-18 67.4 25.9 5.8e-16 58.6 25.9 2.5 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF3446 PF11928.8 PXF41093.1 - 3.4 8.0 6.2 6.4 7.2 6.2 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain WD40 PF00400.32 PXF41095.1 - 2.1e-27 94.8 5.7 1.7e-06 28.6 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PXF41095.1 - 2.3e-26 91.8 0.1 5.8e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 PXF41095.1 - 0.0001 22.2 0.6 0.00049 20.0 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PXF41095.1 - 0.0013 19.0 2.1 0.32 11.3 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TP_methylase PF00590.20 PXF41096.1 - 7.2e-29 101.2 0.1 1.1e-28 100.6 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkr1 PF08636.10 PXF41097.1 - 4.9e-06 26.6 4.6 6.4e-06 26.2 4.6 1.2 1 0 0 1 1 1 1 ER protein Pkr1 GCP_C_terminal PF04130.13 PXF41098.1 - 7e-68 229.4 3.9 1.1e-67 228.7 3.9 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PXF41098.1 - 6e-54 183.7 5.2 6.1e-54 183.7 0.8 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DEC-1_N PF04625.13 PXF41101.1 - 0.0031 16.6 1.2 0.0033 16.5 1.2 1.0 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Alpha_GJ PF03229.13 PXF41101.1 - 0.14 12.7 1.6 0.17 12.4 1.6 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J DEC-1_N PF04625.13 PXF41105.1 - 0.0031 16.6 1.2 0.0033 16.5 1.2 1.0 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Alpha_GJ PF03229.13 PXF41105.1 - 0.14 12.7 1.6 0.17 12.4 1.6 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Nucleoporin_C PF03177.14 PXF41106.1 - 0.00028 19.8 9.0 0.023 13.5 5.0 3.2 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2407_C PF13373.6 PXF41107.1 - 8.9e-14 51.9 0.5 1.2e-12 48.1 0.5 2.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 PXF41107.1 - 0.00082 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PXF41107.1 - 0.0021 18.6 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PXF41107.1 - 0.057 13.5 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like BioY PF02632.14 PXF41107.1 - 0.11 12.5 0.4 0.17 12.0 0.4 1.1 1 0 0 1 1 1 0 BioY family Adaptin_N PF01602.20 PXF41108.1 - 8.7e-121 404.0 0.3 1.2e-120 403.6 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PXF41108.1 - 2.6e-53 180.4 0.1 1.8e-52 177.6 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PXF41108.1 - 1.2e-13 51.2 6.3 9.8e-07 29.1 0.2 5.1 3 1 2 5 5 5 3 HEAT repeats B2-adapt-app_C PF09066.10 PXF41108.1 - 2.8e-08 33.8 0.0 6.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 PXF41108.1 - 1.3e-06 28.2 6.5 0.67 10.4 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 PXF41108.1 - 0.0004 20.3 2.9 0.0027 17.7 0.0 3.7 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 PXF41108.1 - 0.017 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain CLASP_N PF12348.8 PXF41108.1 - 0.13 11.8 0.0 0.81 9.2 0.0 2.2 1 1 0 2 2 2 0 CLASP N terminal Semialdhyde_dh PF01118.24 PXF41109.1 - 1.9e-28 99.4 0.0 3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 PXF41109.1 - 2.4e-20 73.4 0.0 4.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 PXF41109.1 - 0.0091 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 PXF41109.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PXF41109.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 PXF41109.1 - 0.043 14.5 0.0 0.092 13.5 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rad51 PF08423.11 PXF41110.1 - 8e-123 408.7 0.1 9.8e-123 408.4 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 PXF41110.1 - 4.4e-14 52.6 0.1 6.4e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PXF41110.1 - 3.4e-10 39.8 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PXF41110.1 - 7.9e-08 31.9 0.0 1.9e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 PXF41110.1 - 3e-07 30.9 1.7 6.2e-07 29.9 1.0 1.9 1 1 1 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.6 PXF41110.1 - 0.0053 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PXF41110.1 - 0.0062 15.9 0.1 0.14 11.5 0.1 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain MoCF_biosynth PF00994.24 PXF41110.1 - 0.014 15.1 0.2 0.075 12.7 0.1 2.0 2 0 0 2 2 2 0 Probable molybdopterin binding domain AAA_24 PF13479.6 PXF41110.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 PXF41110.1 - 0.18 10.9 1.4 1.1 8.3 0.6 2.2 1 1 1 2 2 2 0 PAXNEB protein Prefoldin PF02996.17 PXF41111.1 - 2.7e-20 72.5 1.4 3.4e-20 72.1 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.12 PXF41111.1 - 0.056 13.5 1.0 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1955 PF09205.10 PXF41111.1 - 0.09 12.5 0.3 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) DUF1664 PF07889.12 PXF41111.1 - 0.42 10.7 3.1 5 7.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 PXF41111.1 - 0.48 10.7 3.8 9.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RRF PF01765.19 PXF41112.1 - 3.5e-43 147.4 6.4 4.6e-43 147.0 6.4 1.1 1 0 0 1 1 1 1 Ribosome recycling factor NICE-3 PF07406.11 PXF41112.1 - 0.075 13.0 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 NICE-3 protein YtxH PF12732.7 PXF41112.1 - 0.13 12.8 6.8 0.068 13.7 4.0 2.0 2 0 0 2 2 2 0 YtxH-like protein AAA PF00004.29 PXF41113.1 - 4.9e-77 256.7 0.0 5.3e-44 149.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF41113.1 - 9.2e-20 70.2 1.8 9.3e-11 41.4 0.5 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PXF41113.1 - 8.6e-12 45.8 7.2 0.0011 19.4 0.2 5.1 2 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 PXF41113.1 - 1.4e-08 34.9 0.0 0.007 16.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PXF41113.1 - 5.1e-08 32.8 0.0 0.015 15.1 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PXF41113.1 - 4.1e-07 30.3 0.0 0.02 15.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PXF41113.1 - 1.3e-06 28.3 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 PXF41113.1 - 9.2e-06 26.0 4.7 0.31 11.3 1.5 5.0 3 2 0 3 3 3 2 AAA domain TIP49 PF06068.13 PXF41113.1 - 1.9e-05 24.1 0.0 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Viral_helicase1 PF01443.18 PXF41113.1 - 6e-05 22.9 0.0 0.079 12.7 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 PXF41113.1 - 7.6e-05 22.8 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PXF41113.1 - 7.7e-05 22.9 0.1 0.16 12.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 PXF41113.1 - 0.00026 20.2 0.0 0.16 11.1 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 PXF41113.1 - 0.00072 19.8 0.0 0.062 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PXF41113.1 - 0.0017 18.3 2.8 0.53 10.2 0.1 4.0 4 1 1 5 5 4 1 NACHT domain Sigma54_activat PF00158.26 PXF41113.1 - 0.002 17.8 0.0 4.6 6.9 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 PXF41113.1 - 0.0051 17.2 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 PXF41113.1 - 0.0067 16.4 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PXF41113.1 - 0.007 16.3 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 PXF41113.1 - 0.0097 15.8 0.0 6.4 6.6 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PXF41113.1 - 0.017 15.7 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 PXF41113.1 - 0.023 15.2 0.1 2.3 8.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PXF41113.1 - 0.032 13.5 0.0 5.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Bac_DnaA PF00308.18 PXF41113.1 - 0.038 13.8 0.0 0.99 9.2 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein ATP-synt_ab PF00006.25 PXF41113.1 - 0.065 12.9 0.0 0.35 10.5 0.0 2.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 PXF41113.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 PXF41113.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PXF41113.1 - 0.078 12.5 0.0 18 4.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PXF41113.1 - 0.079 12.3 0.2 0.68 9.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 PXF41113.1 - 0.081 12.7 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PXF41113.1 - 0.083 12.8 0.0 28 4.5 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 PXF41113.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 PXF41113.1 - 0.14 11.6 0.0 21 4.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 PXF41113.1 - 0.16 11.3 0.0 21 4.4 0.0 2.3 2 0 0 2 2 2 0 KaiC Ribosomal_L7Ae PF01248.26 PXF41114.1 - 7e-26 89.8 0.0 8.2e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 PXF41114.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 PXF41114.1 - 0.0047 17.0 0.0 0.0055 16.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 CSN8_PSD8_EIF3K PF10075.9 PXF41115.1 - 6.6e-20 71.6 0.0 9.4e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PXF41115.1 - 0.0051 16.2 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 PXF41115.1 - 0.038 14.5 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 PCI domain RRM_1 PF00076.22 PXF41116.1 - 6.2e-49 163.7 0.2 1.4e-11 44.0 0.0 7.2 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF41116.1 - 0.016 14.8 0.0 1.1 8.8 0.0 3.3 4 1 1 5 5 5 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0004 PF00919.20 PXF41117.1 - 8.2e-27 93.1 0.0 3.8e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PXF41117.1 - 2.6e-25 89.8 0.1 4.1e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 PXF41117.1 - 2.2e-10 40.3 0.1 4.3e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 TRAM domain TraT PF05818.12 PXF41117.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1937 PF09152.10 PXF41117.1 - 0.056 14.2 0.0 0.16 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1937) Exo_endo_phos PF03372.23 PXF41120.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_2 PF03446.15 PXF41121.1 - 9.5e-49 165.6 0.8 1.3e-48 165.2 0.8 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PXF41121.1 - 8.2e-33 113.2 0.0 1.4e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 PXF41121.1 - 4e-07 30.5 0.0 8.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PXF41121.1 - 2.1e-06 27.2 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF41121.1 - 0.00015 21.9 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PXF41121.1 - 0.00047 20.1 0.1 0.00072 19.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 PXF41121.1 - 0.0037 16.3 0.1 0.0057 15.7 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_10 PF13460.6 PXF41121.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 PXF41121.1 - 0.037 13.3 0.5 0.057 12.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PXF41121.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_47 PF01532.20 PXF41122.1 - 4.2e-105 352.3 0.0 6.2e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RPA_interact_C PF14768.6 PXF41124.1 - 3.8e-14 53.0 1.0 9.1e-14 51.8 1.0 1.6 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Fer2_3 PF13085.6 PXF41124.1 - 0.003 17.5 0.0 0.0099 15.9 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF1840 PF08895.11 PXF41124.1 - 0.23 11.8 2.0 0.34 11.3 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) NINJA_B PF16136.5 PXF41124.1 - 0.84 10.0 4.1 0.7 10.3 1.6 1.9 2 0 0 2 2 2 0 Putative nuclear localisation signal FapA PF03961.13 PXF41124.1 - 1 7.9 2.8 1.3 7.5 2.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PRP1_N PF06424.12 PXF41124.1 - 2.7 8.4 5.1 4.1 7.8 5.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal STAG PF08514.11 PXF41125.1 - 7.5e-18 64.5 0.2 9.5e-17 60.9 0.0 2.7 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 PXF41125.1 - 4e-05 23.9 1.6 0.0045 17.4 0.0 4.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 PXF41125.1 - 0.00012 22.1 0.2 0.0015 18.6 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PXF41125.1 - 0.0055 16.9 9.5 4.3 7.9 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat DUF4042 PF13251.6 PXF41125.1 - 0.0069 16.1 0.2 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) Nipped-B_C PF12830.7 PXF41125.1 - 0.12 12.2 0.0 0.43 10.5 0.0 2.0 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus TFCD_C PF12612.8 PXF41125.1 - 0.26 11.1 1.4 5.5 6.8 0.1 3.0 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal DNA_pol_phi PF04931.13 PXF41126.1 - 2.1e-17 62.6 24.5 2.1e-17 62.6 24.5 3.9 3 1 0 3 3 3 1 DNA polymerase phi DUF563 PF04577.14 PXF41127.1 - 1e-21 78.0 0.0 3.2e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Cyt-b5 PF00173.28 PXF41128.1 - 3.3e-20 72.0 1.1 5e-17 61.8 0.1 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 PXF41128.1 - 3e-12 47.0 19.9 3e-12 47.0 19.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MIP PF00230.20 PXF41130.1 - 2.5e-45 155.0 8.3 4.3e-45 154.2 8.3 1.4 1 1 0 1 1 1 1 Major intrinsic protein TF_Zn_Ribbon PF08271.12 PXF41131.1 - 0.011 15.2 1.1 0.026 14.0 1.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding VKG_Carbox PF05090.14 PXF41131.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase PhnA_Zn_Ribbon PF08274.12 PXF41131.1 - 0.86 9.6 2.7 3.9 7.5 2.7 2.2 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Hist_deacetyl PF00850.19 PXF41132.1 - 1.3e-78 264.6 0.0 1.8e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ANAPC4_WD40 PF12894.7 PXF41133.1 - 4.5e-07 30.1 0.1 0.0055 17.0 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PXF41133.1 - 0.09 10.8 0.9 0.62 8.0 0.4 1.9 2 0 0 2 2 2 0 IKI3 family Ribosomal_60s PF00428.19 PXF41134.1 - 5.6 7.6 14.8 32 5.2 14.8 2.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Methyltransf_25 PF13649.6 PXF41136.1 - 7.6e-13 49.0 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41136.1 - 3.1e-11 43.3 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41136.1 - 1e-08 35.7 0.0 1.7e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41136.1 - 2.6e-07 30.6 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF41136.1 - 2e-06 27.7 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PXF41136.1 - 2.8e-06 28.0 0.0 4.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PXF41136.1 - 9.4e-06 25.4 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.12 PXF41136.1 - 2e-05 24.3 0.0 7.5e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PrmA PF06325.13 PXF41136.1 - 3.4e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 PXF41136.1 - 0.00013 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF41136.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 PXF41136.1 - 0.0013 18.5 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 PXF41136.1 - 0.0019 17.5 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_20 PF12147.8 PXF41136.1 - 0.0073 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 PXF41136.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 PXF41136.1 - 0.032 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.6 PXF41136.1 - 0.06 14.4 0.0 0.12 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 PXF41136.1 - 0.06 12.9 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GCD14 PF08704.10 PXF41136.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4336 PF14234.6 PXF41137.1 - 2.9e-10 39.9 0.2 7.3e-08 32.0 0.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4336) Lactamase_B_5 PF14597.6 PXF41137.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily HEAT_2 PF13646.6 PXF41138.1 - 4.3e-17 62.3 12.0 1.5e-08 34.9 0.9 5.2 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 PXF41138.1 - 0.00059 19.9 2.8 0.26 11.7 0.1 4.5 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 PXF41138.1 - 0.00096 19.1 0.4 0.52 10.4 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 PXF41138.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Herpes_UL14 PF03580.14 PXF41138.1 - 0.081 13.2 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein HEAT_PBS PF03130.16 PXF41138.1 - 0.12 13.1 11.6 0.68 10.8 0.2 6.2 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat DUF647 PF04884.14 PXF41139.1 - 2.9e-59 200.6 0.3 2.9e-59 200.6 0.3 1.5 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis DNA_photolyase PF00875.18 PXF41139.1 - 0.0013 18.8 0.2 0.0047 17.0 0.2 2.0 2 0 0 2 2 2 1 DNA photolyase p450 PF00067.22 PXF41140.1 - 2.3e-81 273.9 0.0 3e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad9 PF04139.13 PXF41141.1 - 1.4e-31 109.8 0.0 1.7e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Sin_N PF04801.13 PXF41142.1 - 9.5e-59 199.7 0.0 1.1e-58 199.4 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region PPTA PF01239.22 PXF41143.1 - 9.6e-24 82.4 16.6 1.8e-07 30.6 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TIMELESS PF04821.14 PXF41145.1 - 1.1e-15 57.7 1.6 1.6e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Timeless protein GMC_oxred_N PF00732.19 PXF41146.1 - 9.7e-35 120.4 0.0 5.3e-34 117.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF41146.1 - 2.1e-16 60.7 0.0 3.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PXF41146.1 - 7.2e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 PXF41146.1 - 0.00067 19.3 0.0 0.044 13.4 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF41146.1 - 0.00068 18.8 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 PXF41146.1 - 0.0054 16.0 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 PXF41146.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PXF41146.1 - 0.065 12.1 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 PXF41146.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.21 PXF41146.1 - 0.18 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 PXF41147.1 - 7.7e-30 103.8 0.0 1e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PXF41147.1 - 7.3e-18 65.0 0.0 1.4e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF41147.1 - 4.3e-08 33.3 0.1 7.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF41147.1 - 0.0047 16.4 0.1 0.011 15.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 PXF41147.1 - 0.042 13.6 0.1 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 PXF41147.1 - 0.055 13.3 0.1 0.2 11.5 0.1 1.8 1 1 0 1 1 1 0 NAD(P)H-binding YjeF_N PF03853.15 PXF41147.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 PXF41147.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GTP_cyclohydroI PF01227.22 PXF41149.1 - 5.6e-67 224.6 0.0 6.5e-67 224.4 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 PXF41149.1 - 0.0093 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DUF2457 PF10446.9 PXF41149.1 - 0.037 13.2 0.6 0.05 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TMEM108 PF15759.5 PXF41149.1 - 0.092 11.7 1.5 0.12 11.4 1.5 1.1 1 0 0 1 1 1 0 TMEM108 family CLP_protease PF00574.23 PXF41150.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Clp protease Cu-oxidase_2 PF07731.14 PXF41151.1 - 8.6e-06 25.5 5.2 6.4e-05 22.7 5.2 2.0 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PXF41152.1 - 0.0001 22.1 5.0 0.00079 19.2 5.0 2.0 1 1 0 1 1 1 1 Multicopper oxidase Nicastrin PF05450.15 PXF41153.1 - 5e-14 52.3 0.0 1.6e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Nicastrin RPAP1_C PF08620.10 PXF41154.1 - 1.4e-20 73.2 0.5 3.9e-20 71.7 0.5 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 PXF41154.1 - 2.1e-10 40.2 0.4 4.5e-10 39.1 0.4 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pkinase_Tyr PF07714.17 PXF41155.1 - 2.2e-63 214.0 0.0 2.9e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF41155.1 - 3.3e-55 187.3 0.0 4.8e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIR_2 PF13676.6 PXF41155.1 - 2.3e-08 34.7 0.0 4.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 PXF41155.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 TIR domain Cu-oxidase_3 PF07732.15 PXF41157.1 - 3.8e-21 75.3 0.1 7e-11 42.2 0.0 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 PXF41157.1 - 3.7e-18 65.6 3.8 7.4e-12 45.2 0.8 5.2 5 1 0 5 5 5 3 Multicopper oxidase Cu-oxidase PF00394.22 PXF41157.1 - 0.055 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Multicopper oxidase SF3b1 PF08920.10 PXF41157.1 - 0.083 13.4 0.4 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 DUF1098 PF06497.11 PXF41160.1 - 0.01 16.3 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) BLOC1_2 PF10046.9 PXF41160.1 - 0.011 16.0 0.3 0.015 15.6 0.3 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OGG_N PF07934.12 PXF41160.1 - 0.038 14.1 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain DnaJ PF00226.31 PXF41161.1 - 4.3e-05 23.6 0.5 0.0001 22.4 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Tau95_N PF17682.1 PXF41161.1 - 0.25 11.5 3.1 0.44 10.7 3.1 1.4 1 1 0 1 1 1 0 Tau95 Triple barrel domain Abi_2 PF07751.11 PXF41161.1 - 0.32 11.2 3.4 0.41 10.9 3.4 1.2 1 0 0 1 1 1 0 Abi-like protein Presenilin PF01080.17 PXF41161.1 - 0.82 8.4 3.4 0.79 8.4 3.4 1.1 1 0 0 1 1 1 0 Presenilin LPD23 PF18838.1 PXF41161.1 - 2.4 8.0 6.4 7.8 6.3 0.0 2.9 2 1 0 2 2 2 0 Large polyvalent protein associated domain 23 TetR_C_30 PF17939.1 PXF41163.1 - 0.056 13.7 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AHD PF17793.1 PXF41163.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Ehrlichia_rpt PF09528.10 PXF41166.1 - 0.015 14.8 0.3 0.029 13.8 0.3 1.4 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) PAN_4 PF14295.6 PXF41168.1 - 0.00013 21.8 5.3 0.00039 20.3 5.3 1.9 1 0 0 1 1 1 1 PAN domain UQ_con PF00179.26 PXF41169.1 - 6e-08 32.4 0.0 7.1e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LBR_tudor PF09465.10 PXF41171.1 - 1.1e-05 25.2 1.3 2.1e-05 24.3 0.5 1.8 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 PXF41171.1 - 0.028 14.1 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 PXF41171.1 - 0.046 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Avl9 PF09794.9 PXF41172.1 - 0.042 12.6 0.1 0.05 12.3 0.1 1.0 1 0 0 1 1 1 0 Transport protein Avl9 TPR_2 PF07719.17 PXF41173.1 - 7.8e-05 22.5 0.1 0.96 9.7 0.0 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF41173.1 - 0.0017 18.6 0.3 0.011 16.0 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF41173.1 - 0.0097 16.7 0.0 0.43 11.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF41173.1 - 0.047 13.5 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF41173.1 - 0.056 14.1 0.0 0.66 10.7 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 PXF41173.1 - 0.057 13.7 0.7 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 PPR repeat TPR_7 PF13176.6 PXF41173.1 - 0.062 13.4 0.3 0.49 10.5 0.0 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF41173.1 - 0.12 12.7 0.0 5.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 PXF41173.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Esterase PF00756.20 PXF41175.1 - 0.0014 18.3 0.1 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 PXF41175.1 - 0.0067 15.9 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1811 PF08838.10 PXF41176.1 - 0.0044 17.2 1.1 0.0061 16.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1811) MbeD_MobD PF04899.12 PXF41176.1 - 0.0052 16.9 1.2 0.01 16.0 0.5 1.9 1 1 1 2 2 2 1 MbeD/MobD like Spc24 PF08286.11 PXF41176.1 - 0.46 10.7 3.6 0.61 10.4 3.6 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 hemP PF10636.9 PXF41178.1 - 0.0088 15.8 2.3 5.6 6.9 0.0 3.4 3 0 0 3 3 3 2 Hemin uptake protein hemP DUF997 PF06196.12 PXF41178.1 - 0.078 13.0 0.2 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Beta_propel PF09826.9 PXF41179.1 - 3.2e-119 399.1 0.0 3.7e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Beta propeller domain DDE_1 PF03184.19 PXF41180.1 - 6.9e-10 38.8 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease gag-asp_proteas PF13975.6 PXF41181.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease VWA PF00092.28 PXF41182.1 - 1.8e-19 70.6 0.5 2.6e-19 70.1 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF41182.1 - 1.2e-10 42.0 0.0 2.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_tran_WecB PF03808.13 PXF41182.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family VWA PF00092.28 PXF41183.1 - 1.8e-19 70.6 0.5 2.6e-19 70.1 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF41183.1 - 1.2e-10 42.0 0.0 2.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_tran_WecB PF03808.13 PXF41183.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family VWA PF00092.28 PXF41184.1 - 6.2e-14 52.6 0.2 1.1e-13 51.8 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF41184.1 - 2.7e-07 31.2 0.0 8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain C_tripleX PF02363.19 PXF41186.1 - 1.1 9.6 5.0 4.9 7.7 5.0 2.2 1 0 0 1 1 1 0 Cysteine rich repeat PID PF00640.23 PXF41188.1 - 0.086 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Chromo PF00385.24 PXF41191.1 - 0.0041 17.0 0.1 0.0088 15.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SLAC1 PF03595.17 PXF41193.1 - 2.8e-24 86.0 46.8 3.2e-24 85.8 46.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pkinase PF00069.25 PXF41194.1 - 6e-15 55.3 0.0 7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AIM24 PF01987.17 PXF41195.1 - 6.2e-21 75.1 0.0 7.6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PCIF1_WW PF12237.8 PXF41196.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Prot_ATP_ID_OB PF16450.5 PXF41200.1 - 0.11 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain WD40 PF00400.32 PXF41201.1 - 6.3e-15 55.3 8.5 0.037 14.9 0.2 6.9 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41201.1 - 8.3e-06 26.0 0.0 3.8 7.9 0.1 4.7 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF41201.1 - 0.019 14.8 0.2 2.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A ACBP PF00887.19 PXF41202.1 - 1.6e-28 98.8 0.1 1.7e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_C12 PF01088.21 PXF41203.1 - 2.1e-64 217.1 0.0 3.3e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PXF41203.1 - 7.7e-14 51.3 0.7 1.4e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases DUF5323 PF17257.2 PXF41204.1 - 1.1e-06 28.3 4.4 1.6e-06 27.9 4.0 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5323) DUF4349 PF14257.6 PXF41205.1 - 0.025 14.0 5.0 0.07 12.6 5.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CHGN PF05679.16 PXF41206.1 - 1.4e-47 162.7 1.0 8.8e-47 160.1 1.0 2.0 1 1 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Aldedh PF00171.22 PXF41207.1 - 1.9e-124 415.7 0.0 2.4e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_11 PF08241.12 PXF41208.1 - 1e-08 35.7 0.2 2.8e-08 34.3 0.2 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41208.1 - 8.4e-08 32.8 0.3 3.3e-07 30.9 0.2 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41208.1 - 1.3e-06 28.3 0.0 2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41208.1 - 1.7e-05 25.5 0.2 6.3e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41208.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF41208.1 - 0.0024 17.2 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Trypsin PF00089.26 PXF41210.1 - 2.5e-38 132.1 0.2 3.2e-38 131.7 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF41210.1 - 3.4e-06 28.0 0.3 7.2e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2207 PF09972.9 PXF41210.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 PXF41210.1 - 0.089 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4834 PF16118.5 PXF41210.1 - 0.18 12.8 0.0 0.47 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-NOSIP PF15906.5 PXF41211.1 - 1.2e-16 60.6 0.1 9e-16 57.8 0.0 2.3 3 0 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 PXF41211.1 - 7.2e-07 29.3 0.6 0.019 15.1 0.0 3.6 4 0 0 4 4 4 2 U-box domain zf-C3HC4_4 PF15227.6 PXF41211.1 - 0.00093 19.3 0.3 0.0024 18.0 0.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 PXF41211.1 - 0.03 13.7 0.0 0.03 13.7 0.0 4.0 1 1 4 5 5 5 0 Rtf2 RING-finger Auto_anti-p27 PF06677.12 PXF41211.1 - 0.12 12.6 1.9 0.36 11.0 1.9 1.9 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CDC45 PF02724.14 PXF41211.1 - 0.17 10.2 3.8 0.2 9.9 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Taxilin PF09728.9 PXF41212.1 - 7.2e-28 97.7 49.2 9.3e-28 97.3 46.1 1.9 1 1 1 2 2 2 1 Myosin-like coiled-coil protein BRE1 PF08647.11 PXF41212.1 - 0.018 15.1 3.9 0.018 15.1 3.9 4.1 2 2 2 4 4 4 0 BRE1 E3 ubiquitin ligase TFIIA PF03153.13 PXF41212.1 - 0.13 12.3 20.6 0.16 12.0 20.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAP1_N PF04849.13 PXF41212.1 - 0.42 9.8 44.3 0.036 13.3 10.4 3.6 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 PXF41212.1 - 0.55 10.3 28.9 3.2 7.8 8.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 PXF41212.1 - 1.4 9.1 36.8 0.48 10.5 5.8 5.4 3 2 1 5 5 5 0 bZIP transcription factor Aminotran_5 PF00266.19 PXF41213.1 - 7.9e-12 44.8 0.0 9.8e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PXF41213.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family NIF PF03031.18 PXF41214.1 - 4.2e-44 150.1 0.1 5.4e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FG-GAP_2 PF14312.6 PXF41214.1 - 0.71 10.2 3.2 1.8 8.9 3.2 1.7 1 0 0 1 1 1 0 FG-GAP repeat V-SNARE_C PF12352.8 PXF41215.1 - 3.7e-07 30.3 2.9 4.8e-07 30.0 0.9 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PXF41215.1 - 0.0031 17.4 0.2 0.013 15.4 0.1 2.1 2 0 0 2 2 2 1 Sec20 DUF3853 PF12964.7 PXF41215.1 - 0.011 15.9 0.5 0.09 13.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Androgen_recep PF02166.16 PXF41215.1 - 0.024 13.5 2.4 0.027 13.3 2.4 1.2 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 PXF41215.1 - 0.096 12.8 5.2 0.19 11.8 5.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Use1 PF09753.9 PXF41215.1 - 0.12 12.1 3.9 0.18 11.5 3.9 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Peptidase_C97 PF05903.14 PXF41216.1 - 1.2e-31 109.6 0.0 1.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Sporozoite_P67 PF05642.11 PXF41216.1 - 1.6 6.7 5.4 2.1 6.3 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hint PF01079.20 PXF41217.1 - 1.6e-20 73.6 0.1 2.2e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Hint module Intein_splicing PF14890.6 PXF41217.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Intein splicing domain Hom_end_hint PF05203.16 PXF41217.1 - 0.02 14.9 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint DUF547 PF04784.14 PXF41218.1 - 3.7e-30 104.5 0.0 7.1e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 V-ATPase_H_C PF11698.8 PXF41219.1 - 1e-34 119.2 0.0 2.2e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 PXF41219.1 - 2e-24 86.5 0.0 9.5e-23 81.0 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 PXF41219.1 - 0.0043 17.1 4.4 0.4 10.8 0.2 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat PolyA_pol_arg_C PF12626.7 PXF41219.1 - 0.069 13.2 0.4 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus Fumble PF03630.14 PXF41220.1 - 2e-119 398.7 0.0 2.4e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Fumble FXR_C3 PF16097.5 PXF41220.1 - 0.12 13.1 6.3 0.35 11.6 6.3 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 Sel1 PF08238.12 PXF41222.1 - 8.3e-22 77.1 2.2 3.4e-06 27.6 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat Mito_carr PF00153.27 PXF41222.1 - 3.8e-19 68.4 0.2 1.1e-09 38.1 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein CS PF04969.16 PXF41222.1 - 1.7e-07 32.1 0.0 3.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 CS domain Tom5 PF10642.9 PXF41222.1 - 0.13 12.3 2.0 0.82 9.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase HEAT_2 PF13646.6 PXF41223.1 - 4.7e-05 23.7 0.6 0.0002 21.7 0.1 2.3 2 1 0 2 2 2 1 HEAT repeats DUF1380 PF07128.12 PXF41226.1 - 0.0077 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1380) SWIM PF04434.17 PXF41226.1 - 0.066 12.9 1.7 0.13 12.0 1.7 1.5 1 0 0 1 1 1 0 SWIM zinc finger EMP24_GP25L PF01105.24 PXF41227.1 - 1.9e-27 96.4 1.0 2.4e-27 96.1 1.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GDE_C PF06202.14 PXF41228.1 - 5.5e-110 367.9 0.0 7.7e-110 367.4 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase GDE_N PF12439.8 PXF41228.1 - 6.2e-60 202.3 0.3 2.2e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 Glycogen debranching enzyme N terminal Bac_rhamnosid6H PF17389.2 PXF41228.1 - 6.9e-05 22.3 0.1 0.00016 21.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 PXF41228.1 - 0.0021 17.0 0.1 0.0043 15.9 0.1 1.5 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 PXF41228.1 - 0.0021 16.8 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain DUF608 PF04685.13 PXF41228.1 - 0.0035 16.5 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region DUF2524 PF10732.9 PXF41229.1 - 0.034 14.5 3.7 0.063 13.6 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DUF2989 PF11207.8 PXF41229.1 - 0.037 13.8 0.7 0.045 13.5 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2989) Hint PF01079.20 PXF41231.1 - 4.3e-23 81.9 0.1 1.6e-22 80.1 0.1 1.7 1 1 0 1 1 1 1 Hint module Hint_2 PF13403.6 PXF41231.1 - 0.0041 17.4 0.1 0.21 11.9 0.0 2.3 2 0 0 2 2 2 1 Hint domain PBP1_TM PF14812.6 PXF41231.1 - 0.024 15.0 4.5 0.041 14.3 4.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 PXF41231.1 - 2.6 8.5 15.8 5.9 7.3 15.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 PXF41231.1 - 4.4 6.5 8.7 6.5 6.0 8.7 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 PXF41231.1 - 5.4 5.0 7.0 7.2 4.6 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPR_long PF17177.4 PXF41232.1 - 0.04 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Mt_ATP-synt_D PF05873.12 PXF41232.1 - 0.054 13.3 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Sif PF06767.11 PXF41232.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.0 1 0 0 1 1 1 0 Sif protein RPAP1_N PF08621.10 PXF41233.1 - 0.012 15.4 0.5 0.027 14.2 0.5 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Nup96 PF12110.8 PXF41233.1 - 0.039 13.1 0.4 0.058 12.5 0.4 1.2 1 0 0 1 1 1 0 Nuclear protein 96 DUF1878 PF08963.10 PXF41233.1 - 0.043 14.3 0.4 0.075 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) CENP-R PF06729.12 PXF41233.1 - 0.7 9.8 3.7 0.96 9.4 3.7 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF1818 PF08848.11 PXF41234.1 - 6.9e-15 55.1 0.0 1e-06 28.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1818) DUF883 PF05957.13 PXF41234.1 - 0.017 15.7 3.4 0.032 14.8 3.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 PXF41234.1 - 0.089 13.1 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WH2 PF02205.20 PXF41234.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 WH2 motif DUF4813 PF16072.5 PXF41234.1 - 0.68 9.5 13.5 1.3 8.6 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) HEAT_2 PF13646.6 PXF41235.1 - 4.4e-17 62.2 1.5 1.6e-09 38.0 0.6 2.5 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 PXF41235.1 - 8.5e-08 31.8 1.8 1.7 9.1 0.2 5.4 6 0 0 6 6 5 1 HEAT repeat HEAT_PBS PF03130.16 PXF41235.1 - 0.0083 16.7 3.0 26 5.9 0.1 4.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 PXF41235.1 - 0.0083 16.2 0.0 0.074 13.1 0.0 2.3 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 PXF41235.1 - 0.014 14.7 0.1 0.075 12.3 0.1 1.9 1 1 0 1 1 1 0 V-ATPase subunit H HEAT_EZ PF13513.6 PXF41235.1 - 0.066 13.7 6.7 20 5.8 0.1 4.0 2 1 2 4 4 4 0 HEAT-like repeat URO-D PF01208.17 PXF41235.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) HTH_Tnp_Mu_1 PF02316.16 PXF41235.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain Adaptin_N PF01602.20 PXF41235.1 - 0.15 10.6 0.1 0.37 9.3 0.1 1.7 1 1 0 1 1 1 0 Adaptin N terminal region TAF6_C PF07571.13 PXF41235.1 - 0.15 12.4 0.1 1.4 9.3 0.0 2.6 2 2 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 PXF41235.1 - 1 9.5 6.8 27 5.0 0.4 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat PCRF PF03462.18 PXF41236.1 - 5e-43 147.2 0.1 5e-43 147.2 0.1 2.1 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 PXF41236.1 - 6.5e-35 119.6 1.7 6.5e-35 119.6 1.7 1.8 2 0 0 2 2 2 1 RF-1 domain Zip PF02535.22 PXF41237.1 - 1.6e-33 116.4 22.7 2.1e-21 76.5 11.3 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1453 PF07301.11 PXF41237.1 - 0.18 11.8 7.9 0.33 11.0 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1453) EVE PF01878.18 PXF41238.1 - 2.2e-45 154.3 0.2 2.8e-45 153.9 0.2 1.1 1 0 0 1 1 1 1 EVE domain TPR_1 PF00515.28 PXF41239.1 - 2.2e-08 33.6 5.2 0.00011 21.9 0.1 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF41239.1 - 2.2e-07 30.5 11.1 0.0032 17.5 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF41239.1 - 0.0035 17.0 2.6 0.25 11.1 1.2 2.9 2 1 0 2 2 2 1 TPR repeat RasGAP PF00616.19 PXF41239.1 - 0.0051 16.6 0.2 0.0072 16.1 0.2 1.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase SMBP PF16785.5 PXF41239.1 - 0.16 12.2 13.2 0.11 12.7 4.8 3.2 1 1 1 3 3 3 0 Small metal-binding protein TPR_12 PF13424.6 PXF41239.1 - 0.21 11.9 13.4 0.21 11.9 0.8 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3263 PF11662.8 PXF41239.1 - 0.22 11.4 4.2 0.27 11.1 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) TPR_7 PF13176.6 PXF41239.1 - 0.25 11.5 8.0 0.4 10.8 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF41239.1 - 0.25 12.0 12.3 0.24 12.1 0.7 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF41239.1 - 2.3 8.7 6.1 45 4.6 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TAFII55_N PF04658.13 PXF41240.1 - 1.8e-26 92.8 1.2 8e-26 90.7 0.0 2.4 2 1 0 2 2 2 1 TAFII55 protein conserved region GCIP PF13324.6 PXF41240.1 - 0.019 14.6 1.6 0.031 13.9 1.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 PXF41240.1 - 0.079 11.5 3.3 0.11 11.0 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 PXF41240.1 - 0.13 12.0 19.3 0.39 10.4 19.3 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 PXF41240.1 - 1.2 9.6 16.5 2.8 8.4 16.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spt5_N PF11942.8 PXF41240.1 - 2.8 9.0 21.6 0.68 10.9 16.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 PXF41240.1 - 7.3 6.6 19.6 1.5 8.9 14.2 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DivIC PF04977.15 PXF41240.1 - 8 6.3 8.3 2.5 7.9 1.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 PXF41241.1 - 0.00044 19.2 17.4 0.0043 16.0 8.7 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF745 PF05335.13 PXF41241.1 - 0.0036 17.1 9.9 0.0049 16.6 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) HrpB7 PF09486.10 PXF41241.1 - 0.0098 16.3 17.9 0.012 16.0 17.9 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Filament PF00038.21 PXF41241.1 - 0.027 14.1 14.1 0.49 9.9 6.5 2.1 1 1 1 2 2 2 0 Intermediate filament protein FPP PF05911.11 PXF41241.1 - 0.027 12.7 13.6 0.081 11.1 13.8 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil MscS_porin PF12795.7 PXF41241.1 - 0.033 13.8 14.9 0.065 12.8 14.9 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain PspA_IM30 PF04012.12 PXF41241.1 - 0.037 13.6 14.6 0.099 12.2 14.6 1.6 1 1 0 1 1 1 0 PspA/IM30 family BRE1 PF08647.11 PXF41241.1 - 0.048 13.7 9.3 0.084 13.0 1.9 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF812 PF05667.11 PXF41241.1 - 0.083 11.8 12.0 0.12 11.3 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spectrin PF00435.21 PXF41241.1 - 0.19 12.3 11.5 0.61 10.6 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF2730 PF10805.8 PXF41241.1 - 0.19 11.8 2.6 0.23 11.6 1.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Phage_GP20 PF06810.11 PXF41241.1 - 0.2 11.4 7.8 0.043 13.6 2.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spc29 PF17082.5 PXF41241.1 - 0.23 11.3 7.6 0.044 13.6 1.6 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 PEARLI-4 PF05278.12 PXF41241.1 - 0.29 10.7 10.7 2.2 7.8 4.8 2.1 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF1664 PF07889.12 PXF41241.1 - 0.4 10.7 6.9 1.2 9.2 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 PXF41241.1 - 0.45 11.1 11.0 0.72 10.5 5.0 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 KxDL PF10241.9 PXF41241.1 - 0.68 10.3 7.5 3.6 7.9 0.5 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein YscO PF07321.12 PXF41241.1 - 0.69 9.9 23.1 2.7 8.0 14.3 2.8 1 1 1 2 2 2 0 Type III secretion protein YscO TSNAXIP1_N PF15739.5 PXF41241.1 - 0.76 10.2 8.3 0.58 10.6 2.2 2.2 1 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Exonuc_VII_L PF02601.15 PXF41241.1 - 0.85 9.1 13.2 1.6 8.2 13.2 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 PXF41241.1 - 0.98 9.8 7.8 3.2 8.1 1.9 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 PXF41241.1 - 1 8.0 11.4 1.8 7.1 11.4 1.4 1 1 0 1 1 1 0 AAA domain ADIP PF11559.8 PXF41241.1 - 1.3 9.1 17.4 27 4.8 10.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 PXF41241.1 - 1.4 8.2 13.9 1.1 8.5 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 PXF41241.1 - 1.4 9.1 19.9 30 4.8 19.9 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 PXF41241.1 - 1.7 9.3 5.6 0.53 10.9 0.2 2.5 1 1 0 2 2 2 0 SlyX FliD_N PF02465.18 PXF41241.1 - 1.9 9.3 7.8 2.3 8.9 2.8 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Rx_N PF18052.1 PXF41241.1 - 2.1 8.7 9.1 1.6 9.0 0.5 2.9 1 1 2 3 3 3 0 Rx N-terminal domain FAM76 PF16046.5 PXF41241.1 - 2.2 7.6 9.9 3 7.1 9.9 1.2 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 PXF41241.1 - 2.2 8.3 13.1 4.8 7.2 13.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 PXF41241.1 - 2.4 8.3 7.9 1.8 8.8 1.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 PXF41241.1 - 2.8 8.4 17.2 3.6 8.1 15.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 PXF41241.1 - 2.9 7.9 23.0 1.6 8.8 4.5 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HemX PF04375.14 PXF41241.1 - 3.6 6.8 14.0 1.6e+02 1.4 14.0 2.0 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Prefoldin PF02996.17 PXF41241.1 - 3.7 7.5 9.8 1.7 8.6 0.9 3.0 1 1 0 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 PXF41241.1 - 3.8 7.5 17.6 8.6 6.4 17.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 PXF41241.1 - 4.3 6.6 13.5 8.5 5.6 13.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 PXF41241.1 - 4.6 7.6 18.2 34 4.8 15.2 2.0 1 1 1 2 2 2 0 Fez1 DUF4200 PF13863.6 PXF41241.1 - 5.1 7.5 18.0 3.9 7.9 6.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) YlqD PF11068.8 PXF41241.1 - 9 6.7 11.7 4.4 7.7 6.2 2.0 1 1 1 2 2 2 0 YlqD protein RNA_polI_A34 PF08208.11 PXF41242.1 - 0.0016 18.6 2.2 0.0026 17.9 2.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 bZIP_Maf PF03131.17 PXF41242.1 - 0.074 13.6 14.0 0.15 12.6 14.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 PXF41242.1 - 0.11 12.6 19.3 0.06 13.4 17.1 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Surp PF01805.20 PXF41242.1 - 2.7 8.1 3.7 21 5.2 0.4 2.4 2 0 0 2 2 2 0 Surp module CENP-H PF05837.12 PXF41242.1 - 3.2 8.2 10.1 5.9 7.4 10.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PPR_2 PF13041.6 PXF41243.1 - 2.3e-51 171.8 9.3 1.3e-13 50.9 0.0 11.9 7 4 5 12 12 12 11 PPR repeat family PPR PF01535.20 PXF41243.1 - 6.7e-38 126.3 7.8 6.3e-07 29.2 0.0 12.8 13 1 0 13 13 13 4 PPR repeat PPR_3 PF13812.6 PXF41243.1 - 7.9e-33 112.3 0.0 5e-13 48.9 0.0 7.6 6 2 1 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF41243.1 - 4.6e-30 103.0 5.9 5.2e-10 38.9 0.0 10.2 13 0 0 13 13 13 4 PPR repeat PPR_long PF17177.4 PXF41243.1 - 7e-21 74.6 0.1 5.3e-07 29.2 0.0 5.1 3 1 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PXF41243.1 - 0.0042 17.6 0.1 19 5.9 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF41243.1 - 0.0059 16.5 0.1 63 3.9 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF41243.1 - 0.025 15.2 0.6 43 5.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF41243.1 - 0.3 12.0 4.0 2.3e+02 3.0 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Mic1 PF07035.12 PXF41243.1 - 1.3 8.7 5.1 7.3 6.3 0.0 3.3 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like ABC_tran PF00005.27 PXF41245.1 - 2.4e-46 157.6 0.0 1e-24 87.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PXF41245.1 - 1.6e-17 63.3 5.8 7.8e-14 51.5 5.4 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PXF41245.1 - 4.4e-17 62.9 4.2 1.7e-08 34.6 3.9 3.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF41245.1 - 1.1e-07 31.5 3.7 0.22 10.9 1.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PXF41245.1 - 1.5e-06 28.7 1.0 0.0087 16.5 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 PXF41245.1 - 2.6e-06 28.1 6.7 0.001 19.6 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PXF41245.1 - 9.7e-06 25.2 1.3 0.036 13.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF41245.1 - 4e-05 23.9 0.2 0.036 14.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PXF41245.1 - 0.00016 21.8 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 PXF41245.1 - 0.0002 21.4 0.4 0.69 10.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_13 PF13166.6 PXF41245.1 - 0.00024 19.9 0.4 0.28 9.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain Roc PF08477.13 PXF41245.1 - 0.00037 20.7 0.1 1.3 9.3 0.0 2.8 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PXF41245.1 - 0.0007 19.5 0.1 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 PXF41245.1 - 0.001 18.9 3.1 0.75 9.4 1.2 2.5 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 PXF41245.1 - 0.0026 17.7 1.7 0.64 9.9 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 PXF41245.1 - 0.0032 17.6 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF41245.1 - 0.0032 17.2 0.1 1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 PXF41245.1 - 0.0032 17.1 0.3 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 PXF41245.1 - 0.0042 17.6 0.0 5.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PXF41245.1 - 0.0055 17.1 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PXF41245.1 - 0.0072 16.1 0.6 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PXF41245.1 - 0.0091 15.2 1.4 0.54 9.4 0.0 2.9 4 0 0 4 4 3 1 NB-ARC domain RecA PF00154.21 PXF41245.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PduV-EutP PF10662.9 PXF41245.1 - 0.019 14.7 0.1 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 PXF41245.1 - 0.021 14.5 0.3 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PXF41245.1 - 0.043 13.7 0.6 5 7.0 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 PXF41245.1 - 0.087 13.1 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 PXF41245.1 - 0.093 13.0 0.1 8 6.8 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 PXF41245.1 - 0.11 11.8 0.2 4.7 6.4 0.1 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 PXF41245.1 - 0.15 12.1 0.0 1.2 9.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 PXF41245.1 - 0.16 12.0 0.9 7.1 6.7 0.1 3.2 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNase_H2-Ydr279 PF09468.10 PXF41245.1 - 0.23 11.7 0.4 0.59 10.3 0.2 1.7 2 0 0 2 2 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DLIC PF05783.11 PXF41245.1 - 1 8.1 5.4 1.4 7.6 0.0 2.5 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) PfkB PF00294.24 PXF41246.1 - 4.5e-49 167.4 0.0 5.8e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase peroxidase PF00141.23 PXF41247.1 - 2.2e-46 158.4 0.0 3.2e-46 157.9 0.0 1.2 1 1 0 1 1 1 1 Peroxidase VCBS PF13517.6 PXF41248.1 - 3.1e-20 72.5 24.1 1.4e-06 28.8 1.5 5.6 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF41248.1 - 3.1e-08 33.6 23.8 0.95 9.7 0.1 6.9 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 PXF41248.1 - 0.021 14.2 0.7 5.3 6.4 0.0 3.7 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.32 PXF41248.1 - 3.7 7.3 6.8 38 4.2 0.0 4.2 5 0 0 5 5 5 0 EF hand CBFD_NFYB_HMF PF00808.23 PXF41249.1 - 5.6e-23 81.0 1.0 1.3e-22 79.9 1.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF41249.1 - 5.3e-18 65.6 3.1 8.4e-18 65.0 3.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 PXF41249.1 - 0.018 15.2 0.7 0.046 13.9 0.7 1.7 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-X PF09415.10 PXF41249.1 - 0.074 13.4 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X CMAS PF02353.20 PXF41250.1 - 4.7e-98 327.8 1.4 5.7e-98 327.6 1.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 PXF41250.1 - 5.9e-17 62.2 0.0 1.4e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41250.1 - 3.9e-14 53.1 0.0 9.2e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41250.1 - 1.2e-11 44.6 0.0 4.4e-11 42.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41250.1 - 2.8e-11 43.6 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41250.1 - 2.8e-11 44.0 0.0 1.3e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PXF41250.1 - 2e-07 30.7 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PXF41250.1 - 8e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PXF41250.1 - 9e-06 25.7 0.1 1.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF41250.1 - 0.00017 21.0 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PXF41250.1 - 0.00026 20.8 0.1 0.00039 20.2 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 PXF41250.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.26 PXF41250.1 - 0.0008 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MetW PF07021.12 PXF41250.1 - 0.0026 17.4 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 PXF41250.1 - 0.0045 16.0 0.2 0.0087 15.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 PXF41250.1 - 0.0049 16.9 0.1 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 PXF41250.1 - 0.013 15.4 0.1 0.21 11.4 0.1 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 PXF41250.1 - 0.017 14.3 0.0 2.7 7.1 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 PXF41250.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase UPF0020 PF01170.18 PXF41250.1 - 0.04 13.6 0.1 0.21 11.2 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 PXF41250.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain N2227 PF07942.12 PXF41250.1 - 0.079 12.1 0.0 0.7 9.0 0.0 2.0 1 1 1 2 2 2 0 N2227-like protein FIST PF08495.10 PXF41251.1 - 2.5e-14 53.6 0.0 5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 PXF41251.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 FIST C domain RNA_pol_Rpb1_1 PF04997.12 PXF41252.1 - 5.4e-82 275.6 0.1 8.7e-82 274.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 PXF41252.1 - 1.4e-80 270.6 0.1 2.1e-80 270.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PXF41252.1 - 9.9e-73 243.8 0.0 2e-72 242.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PXF41252.1 - 4.8e-34 117.6 0.0 1.2e-33 116.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PXF41252.1 - 8.3e-21 74.0 0.0 2.3e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2458 PF10454.9 PXF41252.1 - 0.17 11.5 1.1 3.5 7.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) zf-ISL3 PF14690.6 PXF41252.1 - 0.81 10.4 3.8 0.56 10.9 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FBPase PF00316.20 PXF41253.1 - 6.1e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Cys_rich_VLP PF14194.6 PXF41253.1 - 0.17 12.1 1.4 0.35 11.0 0.0 2.2 3 0 0 3 3 3 0 Cysteine-rich VLP RRM_1 PF00076.22 PXF41254.1 - 9e-83 272.1 1.4 7.7e-20 70.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 PXF41254.1 - 8.5e-27 93.1 0.6 1.7e-26 92.2 0.6 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 PXF41254.1 - 1.4e-14 53.8 0.0 5.7e-06 25.9 0.0 4.5 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PXF41254.1 - 4.4e-08 33.1 0.9 0.046 13.8 0.2 4.2 4 0 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 PXF41254.1 - 5.9e-06 26.3 0.2 0.79 9.9 0.0 4.4 3 1 1 4 4 4 2 RNA recognition motif SET_assoc PF11767.8 PXF41254.1 - 8.6e-06 25.3 0.1 5.9 6.6 0.0 4.4 4 0 0 4 4 4 3 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 PXF41254.1 - 1.4e-05 24.8 0.0 0.21 11.5 0.0 3.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PXF41254.1 - 7.3e-05 22.7 0.1 0.4 10.7 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PXF41254.1 - 0.00034 20.6 2.8 0.055 13.5 0.0 4.0 5 0 0 5 5 5 1 Limkain b1 PHM7_cyt PF14703.6 PXF41254.1 - 0.0005 20.3 0.8 15 5.8 0.0 4.8 4 1 1 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter NAD_binding_10 PF13460.6 PXF41255.1 - 8.7e-23 81.2 0.1 1.2e-22 80.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF41255.1 - 6.2e-16 58.7 0.0 1.1e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF41255.1 - 2.2e-12 46.9 0.3 7.5e-12 45.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF41255.1 - 3.4e-07 29.5 0.1 4.9e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PXF41255.1 - 2.2e-06 27.3 0.1 3e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 PXF41255.1 - 1.9e-05 24.2 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 PXF41255.1 - 9.1e-05 21.7 0.0 0.00014 21.1 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 PXF41255.1 - 0.0015 18.1 0.1 0.0034 17.0 0.1 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF41255.1 - 0.0036 17.2 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 PXF41255.1 - 0.0095 15.1 0.0 0.041 13.0 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PXF41255.1 - 0.094 11.9 0.0 0.3 10.2 0.0 1.9 1 1 1 2 2 2 0 Male sterility protein Ribosomal_S28e PF01200.18 PXF41256.1 - 8.6e-31 105.7 0.3 8.6e-31 105.7 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S28e MutS_V PF00488.21 PXF41257.1 - 9.3e-65 218.2 0.0 1.7e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PXF41257.1 - 4.4e-32 111.8 0.0 3.8e-31 108.8 0.0 2.6 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PXF41257.1 - 8.2e-25 87.2 0.0 2.7e-24 85.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 PXF41257.1 - 8.6e-15 54.9 0.0 2.6e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PXF41257.1 - 3.4e-14 53.3 0.0 9e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 PXF41257.1 - 0.077 12.6 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PXF41258.1 - 1.6e-42 145.7 0.0 5e-42 144.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41258.1 - 4.6e-39 134.3 0.2 1.4e-19 70.4 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase EF-hand_1 PF00036.32 PXF41258.1 - 5e-10 38.2 1.8 0.00048 19.5 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 PXF41258.1 - 2.4e-08 33.1 0.1 0.00023 20.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PXF41258.1 - 3.9e-08 33.6 0.5 3.1e-07 30.7 0.0 2.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 PXF41258.1 - 4.2e-08 32.5 0.7 0.015 15.2 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PXF41258.1 - 9.5e-08 31.8 0.4 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair APH PF01636.23 PXF41258.1 - 2.7e-07 30.8 0.0 4.4e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF41258.1 - 3.7e-05 23.4 0.0 8.8e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 PXF41258.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_10 PF14788.6 PXF41258.1 - 0.0097 15.8 0.6 6.2 6.8 0.1 3.0 2 0 0 2 2 2 2 EF hand Pkinase_fungal PF17667.1 PXF41258.1 - 0.081 11.7 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAXX PF15384.6 PXF41259.1 - 0.032 13.9 0.0 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 GCK PF07802.11 PXF41260.1 - 5.1e-06 26.8 2.9 9.1e-06 26.0 2.9 1.4 1 0 0 1 1 1 1 GCK domain RHH_1 PF01402.21 PXF41260.1 - 0.081 12.9 1.5 0.15 12.1 1.5 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family CHCH PF06747.13 PXF41260.1 - 0.38 10.9 5.3 0.69 10.1 5.3 1.5 1 0 0 1 1 1 0 CHCH domain ABC_membrane_2 PF06472.15 PXF41261.1 - 4.9e-34 118.0 2.3 7.7e-34 117.3 2.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF41261.1 - 1.5e-16 61.1 0.0 2.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 PXF41261.1 - 0.00058 19.6 0.0 0.0058 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 PXF41261.1 - 0.027 14.3 0.0 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF41262.1 - 5.3e-63 212.4 19.1 1.6e-62 210.8 19.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PXF41262.1 - 1.3e-26 93.2 1.6 7e-26 90.8 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PXF41262.1 - 2.2e-14 54.0 10.0 9.3e-08 32.2 0.8 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PXF41262.1 - 7.2e-13 49.0 40.4 1.5e-07 31.4 6.0 4.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 PXF41262.1 - 1.4e-06 28.9 32.7 1.4e-06 28.9 32.7 6.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PXF41262.1 - 0.00049 19.8 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HAMP_N3 PF18575.1 PXF41262.1 - 0.37 10.4 2.9 3.8 7.2 0.1 3.4 3 0 0 3 3 3 0 HAMP N-terminal domain 3 Spc7 PF08317.11 PXF41262.1 - 7.1 5.4 113.3 1 8.2 15.6 6.1 2 2 4 6 6 6 0 Spc7 kinetochore protein Peptidase_M41 PF01434.18 PXF41264.1 - 2e-60 203.9 0.0 3.1e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PXF41264.1 - 2e-41 141.5 0.0 4.1e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF41264.1 - 3.2e-11 42.8 0.1 9.4e-11 41.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 PXF41264.1 - 3.3e-08 33.8 0.0 9.9e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 PXF41264.1 - 0.00025 21.3 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PXF41264.1 - 0.0011 19.0 0.0 0.0056 16.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PXF41264.1 - 0.0016 18.8 2.1 0.086 13.2 0.1 3.6 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 PXF41264.1 - 0.0053 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PXF41264.1 - 0.034 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 PXF41264.1 - 0.055 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 PXF41264.1 - 0.066 13.3 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PXF41264.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PXF41264.1 - 0.076 12.4 0.2 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Plasmodium_Vir PF05795.11 PXF41264.1 - 0.15 11.5 1.3 10 5.4 0.9 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein WD40 PF00400.32 PXF41265.1 - 0.00028 21.6 8.4 0.12 13.2 0.7 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ras PF00071.22 PXF41266.1 - 2.8e-63 212.3 0.3 3.4e-63 212.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF41266.1 - 4.8e-35 120.4 0.1 8.6e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF41266.1 - 2.8e-13 49.7 0.0 3.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PXF41266.1 - 8.8e-07 29.0 0.1 1.2e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF41266.1 - 0.00022 21.2 0.8 0.24 11.3 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PXF41266.1 - 0.00071 19.2 0.2 0.0043 16.6 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PXF41266.1 - 0.001 18.5 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PXF41266.1 - 0.0036 17.1 0.0 0.0092 15.7 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PXF41266.1 - 0.0052 17.2 0.0 0.0082 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 PXF41266.1 - 0.0054 16.3 0.1 0.063 12.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 PXF41266.1 - 0.027 14.7 0.1 0.13 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain YtzH PF14165.6 PXF41266.1 - 0.039 14.3 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 YtzH-like protein AAA_14 PF13173.6 PXF41266.1 - 0.067 13.2 0.2 0.34 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 PXF41266.1 - 0.093 11.8 0.0 0.28 10.3 0.0 1.7 1 1 1 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 PXF41266.1 - 0.14 12.7 0.1 0.27 11.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 PXF41266.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 PXF41266.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 PXF41267.1 - 2e-61 206.3 0.3 2.5e-61 206.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF41267.1 - 9.7e-35 119.4 0.1 1.8e-34 118.5 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF41267.1 - 3.3e-14 52.7 0.1 4.2e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PXF41267.1 - 3.8e-07 30.2 0.1 0.022 14.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PXF41267.1 - 5.5e-06 26.4 0.1 7.9e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PXF41267.1 - 0.00053 19.6 0.1 0.0016 18.0 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PXF41267.1 - 0.0097 15.5 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_22 PF13401.6 PXF41267.1 - 0.022 15.0 0.0 0.05 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF41267.1 - 0.057 13.8 0.1 0.092 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PXF41267.1 - 0.07 13.6 0.2 0.11 13.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 PXF41267.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain BPL_LplA_LipB PF03099.19 PXF41268.1 - 4.1e-09 36.4 0.0 6.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SLC12 PF03522.15 PXF41269.1 - 0.14 11.1 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TPM_phosphatase PF04536.14 PXF41270.1 - 8.8e-14 51.8 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 TPM domain ANAPC4_WD40 PF12894.7 PXF41271.1 - 6.9e-06 26.3 1.9 1 9.7 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF41271.1 - 0.079 13.9 10.9 5.3 8.1 0.0 6.0 6 1 0 7 7 7 0 WD domain, G-beta repeat 5_nucleotid PF05761.14 PXF41272.1 - 2.1e-152 508.2 0.0 2.4e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family DUF1664 PF07889.12 PXF41272.1 - 0.0071 16.4 0.3 0.33 11.0 0.1 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) Retrotrans_gag PF03732.17 PXF41272.1 - 0.029 14.6 1.3 1.2 9.5 0.2 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein SHE3 PF17078.5 PXF41272.1 - 0.059 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CdvA PF18822.1 PXF41272.1 - 0.1 12.4 2.6 0.25 11.2 0.2 2.5 2 1 1 3 3 3 0 CdvA-like coiled-coil domain Glu-tRNAGln PF02686.15 PXF41272.1 - 0.2 12.0 0.4 0.44 10.9 0.4 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Seryl_tRNA_N PF02403.22 PXF41272.1 - 0.21 11.9 2.2 0.4 10.9 2.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TetR_C_24 PF17932.1 PXF41272.1 - 0.37 11.1 2.5 19 5.6 0.1 3.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FlaC_arch PF05377.11 PXF41272.1 - 0.47 10.9 4.0 2.4 8.6 1.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pro_isomerase PF00160.21 PXF41274.1 - 1.5e-50 171.5 0.1 1.9e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thg1 PF04446.12 PXF41275.1 - 2.5e-48 163.2 0.3 6.6e-48 161.9 0.1 1.7 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 PXF41275.1 - 4.8e-42 143.0 0.1 7.6e-42 142.3 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Hint PF01079.20 PXF41276.1 - 1.6e-27 96.4 0.1 3.5e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Hint module Rotamase PF00639.21 PXF41277.1 - 1.8e-20 73.7 0.0 2.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PXF41277.1 - 1.8e-19 70.4 0.0 3.3e-19 69.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PXF41277.1 - 5e-06 27.4 0.1 1.3e-05 26.0 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Complex1_49kDa PF00346.19 PXF41279.1 - 1.7e-124 414.3 0.0 2e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Catalase PF00199.19 PXF41280.1 - 3.4e-161 536.6 0.0 4.1e-161 536.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PXF41280.1 - 2e-14 53.5 0.0 4.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive AATF-Che1 PF13339.6 PXF41281.1 - 0.16 12.6 0.1 0.16 12.6 0.1 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Transposase_21 PF02992.14 PXF41282.1 - 2.2e-06 27.1 0.0 3.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 PXF41283.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) ATP-synt_ab PF00006.25 PXF41284.1 - 4.2e-72 242.3 0.0 6.1e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 PXF41284.1 - 2e-46 157.4 0.2 3.5e-46 156.6 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 PXF41284.1 - 1.3e-17 64.0 0.9 4e-17 62.5 0.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4142 PF13628.6 PXF41284.1 - 0.0021 18.3 1.6 0.0047 17.2 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) HAS-barrel PF09378.10 PXF41284.1 - 0.007 16.5 0.1 0.018 15.2 0.1 1.8 1 1 0 1 1 1 1 HAS barrel domain Ins_P5_2-kin PF06090.12 PXF41286.1 - 5.9e-30 104.8 0.0 6.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase VWA PF00092.28 PXF41287.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain PilN PF05137.13 PXF41289.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) DUF5554 PF17709.1 PXF41290.1 - 0.16 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5554) WD40 PF00400.32 PXF41292.1 - 2.7e-19 69.2 9.2 1.4e-07 32.1 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41292.1 - 7.9e-10 38.9 0.0 0.38 11.1 0.0 5.0 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 PXF41292.1 - 0.14 10.4 0.0 2.7 6.2 0.0 2.3 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz S1 PF00575.23 PXF41293.1 - 1.4e-29 102.3 19.9 2.2e-06 27.9 0.1 10.1 10 0 0 10 10 10 5 S1 RNA binding domain Suf PF05843.14 PXF41293.1 - 2e-09 37.9 4.7 0.0012 18.9 1.5 3.7 3 1 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 PXF41293.1 - 9.5e-06 26.0 0.1 0.31 11.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 PXF41293.1 - 0.00015 21.0 0.6 0.11 11.6 0.0 3.0 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 PXF41293.1 - 0.00018 22.0 0.1 0.0026 18.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 PXF41293.1 - 0.0013 18.6 4.7 0.071 13.1 0.0 5.2 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 PXF41293.1 - 0.0034 18.1 0.3 4.8 8.3 0.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF41293.1 - 0.074 13.2 0.0 0.89 9.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RGS_DHEX PF18148.1 PXF41294.1 - 1.2 9.3 8.2 0.45 10.7 1.5 2.6 1 1 1 2 2 2 0 Regulator of G-protein signalling DHEX domain Ank_5 PF13857.6 PXF41295.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Helicase_C PF00271.31 PXF41296.1 - 6.5e-07 29.7 0.1 3e-06 27.6 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain SLAC1 PF03595.17 PXF41297.1 - 3.6e-27 95.5 41.5 4.2e-27 95.2 41.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4389 PF14333.6 PXF41297.1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4389) TMIE PF16038.5 PXF41297.1 - 0.16 11.8 2.8 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 TMIE protein DNA_pol_delta_4 PF04081.13 PXF41299.1 - 3e-12 47.0 1.8 4.4e-12 46.5 1.8 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Mei5 PF10376.9 PXF41299.1 - 0.014 15.2 1.0 0.016 15.1 1.0 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein 5-FTHF_cyc-lig PF01812.20 PXF41299.1 - 0.08 12.8 1.4 0.098 12.5 1.4 1.2 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family RabGAP-TBC PF00566.18 PXF41300.1 - 1.8e-45 155.2 1.0 7.6e-44 149.9 0.1 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain NUDIX PF00293.28 PXF41301.1 - 1.4e-11 44.5 0.1 2.3e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 PXF41301.1 - 7.4e-06 26.6 0.0 2.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 PXF41301.1 - 5.8e-05 22.7 3.2 0.00011 21.7 3.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain RecR PF02132.15 PXF41301.1 - 0.03 13.9 0.2 0.067 12.8 0.2 1.6 1 0 0 1 1 1 0 RecR protein TMEM82 PF15816.5 PXF41301.1 - 0.03 13.3 0.2 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 eIF-6 PF01912.18 PXF41305.1 - 2.9e-79 265.0 0.5 4.9e-79 264.3 0.3 1.4 2 0 0 2 2 2 1 eIF-6 family GCP_C_terminal PF04130.13 PXF41306.1 - 1.2e-20 74.2 0.7 1e-19 71.2 0.7 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PXF41306.1 - 0.066 12.8 1.8 0.32 10.6 0.1 2.9 2 2 1 3 3 3 0 Gamma tubulin complex component N-terminal ATP_bind_1 PF03029.17 PXF41307.1 - 2.7e-72 243.5 0.1 3.2e-72 243.2 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 PXF41307.1 - 0.00011 22.2 0.0 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 PXF41307.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 6PF2K PF01591.18 PXF41307.1 - 0.0066 15.8 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase SRP54 PF00448.22 PXF41307.1 - 0.0072 16.0 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 PXF41307.1 - 0.0081 16.3 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PXF41307.1 - 0.021 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 PXF41307.1 - 0.023 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.6 PXF41307.1 - 0.023 15.1 0.1 0.056 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain WSD PF15613.6 PXF41307.1 - 0.025 15.1 0.2 0.94 10.0 0.1 2.9 2 1 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif CLP1_P PF16575.5 PXF41307.1 - 0.033 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 PXF41307.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PXF41307.1 - 0.035 14.7 1.1 0.17 12.4 0.3 2.5 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 PXF41307.1 - 0.048 13.3 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Zeta_toxin PF06414.12 PXF41307.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 PXF41307.1 - 0.074 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PXF41307.1 - 0.074 13.3 0.1 0.19 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF41307.1 - 0.074 13.4 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 PXF41307.1 - 0.13 11.3 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 PXF41307.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Complex1_51K PF01512.17 PXF41309.1 - 7.2e-47 159.1 0.0 1e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 PXF41309.1 - 1.4e-29 102.0 0.0 2.8e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 PXF41309.1 - 7.3e-08 32.2 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 SLBB domain GHMP_kinases_C PF08544.13 PXF41309.1 - 0.038 14.3 0.1 11 6.5 0.0 2.8 2 0 0 2 2 2 0 GHMP kinases C terminal DUF780 PF05611.11 PXF41309.1 - 0.095 13.5 2.4 0.11 13.3 0.8 1.9 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) Rep_fac_C PF08542.11 PXF41310.1 - 1.7e-18 66.8 0.0 3.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 PXF41310.1 - 1e-15 58.3 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PXF41310.1 - 2.5e-12 46.9 0.0 7.6e-11 42.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 PXF41310.1 - 2.7e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 PXF41310.1 - 6.7e-07 29.4 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PXF41310.1 - 3.2e-06 27.1 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PXF41310.1 - 3.4e-06 27.5 0.1 0.00058 20.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PXF41310.1 - 9.8e-06 25.4 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF41310.1 - 0.00012 22.3 0.1 0.051 13.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PXF41310.1 - 0.00029 20.3 0.0 0.0068 15.8 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PXF41310.1 - 0.00035 20.6 0.1 0.0018 18.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PXF41310.1 - 0.00075 20.0 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 PXF41310.1 - 0.00077 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PXF41310.1 - 0.0028 18.2 0.0 0.0067 16.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 PXF41310.1 - 0.0033 17.8 0.4 0.012 16.0 0.4 2.2 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 PXF41310.1 - 0.0053 16.2 0.1 0.057 12.8 0.0 2.3 3 0 0 3 3 3 1 Bacterial TniB protein AAA_11 PF13086.6 PXF41310.1 - 0.0057 16.5 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PXF41310.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 PXF41310.1 - 0.0099 15.3 0.0 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 PXF41310.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PXF41310.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PXF41310.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PXF41310.1 - 0.019 15.3 0.0 0.047 14.1 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 PXF41310.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 PXF41310.1 - 0.039 12.9 0.2 0.16 10.9 0.0 1.9 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PXF41310.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PXF41310.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 PXF41310.1 - 0.057 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 PXF41310.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 PXF41310.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF5119 PF17145.4 PXF41310.1 - 0.073 13.0 0.0 16 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) TIP49 PF06068.13 PXF41310.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 PXF41310.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 PXF41310.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase UCH PF00443.29 PXF41311.1 - 4.1e-44 151.0 0.0 7e-44 150.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF41311.1 - 3.9e-14 53.0 0.1 3.6e-11 43.2 0.1 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAP_N PF01213.19 PXF41311.1 - 0.07 12.6 13.4 0.17 11.3 13.4 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PXF41311.1 - 0.69 10.0 15.1 0.099 12.7 8.4 2.6 2 0 0 2 2 2 0 Mitochondrial fission regulator SSB PF00436.25 PXF41312.1 - 1.4e-21 76.5 0.0 2.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family DUF676 PF05057.14 PXF41314.1 - 6e-22 78.2 0.1 8.1e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 PXF41314.1 - 0.00015 21.5 0.2 0.00027 20.7 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 PXF41314.1 - 0.0012 18.8 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 PXF41314.1 - 0.0028 17.5 0.1 0.69 9.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PXF41314.1 - 0.063 13.9 0.5 0.097 13.3 0.5 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 PXF41314.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 PXF41314.1 - 0.2 11.6 0.8 0.35 10.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Beta_propel PF09826.9 PXF41315.1 - 3.2e-127 425.5 0.0 3.6e-127 425.3 0.0 1.0 1 0 0 1 1 1 1 Beta propeller domain C2 PF00168.30 PXF41319.1 - 7.3e-05 23.0 0.1 0.0001 22.5 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF2914 PF11141.8 PXF41319.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) TPT PF03151.16 PXF41320.1 - 1.7e-21 76.9 14.8 1.9e-21 76.7 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PXF41320.1 - 0.00069 18.9 16.6 0.0011 18.2 16.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF41320.1 - 0.0072 16.5 28.5 0.026 14.7 7.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family WTF PF03303.13 PXF41320.1 - 5.3 6.7 13.3 0.34 10.6 2.1 2.5 2 1 1 3 3 3 0 WTF protein CRAL_TRIO_2 PF13716.6 PXF41321.1 - 7.3e-20 71.5 0.0 8.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cation_efflux PF01545.21 PXF41321.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family zf-H2C2_2 PF13465.6 PXF41322.1 - 2.2e-05 24.7 3.7 0.0013 19.0 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 PXF41322.1 - 0.00083 19.7 0.8 0.00083 19.7 0.8 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF41322.1 - 0.029 15.2 3.7 0.067 14.1 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PXF41322.1 - 0.052 13.5 0.6 0.32 10.9 1.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MCM_OB PF17207.3 PXF41322.1 - 0.13 12.1 0.7 0.33 10.8 0.7 1.6 1 0 0 1 1 1 0 MCM OB domain Zn_ribbon_SprT PF17283.2 PXF41322.1 - 4 7.4 6.1 2.8 7.9 1.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Glyoxalase PF00903.25 PXF41323.1 - 5.9e-07 29.7 0.0 3.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF41323.1 - 0.012 16.4 0.0 0.019 15.7 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 PXF41323.1 - 0.09 13.1 0.0 2.7 8.3 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cation_ATPase_C PF00689.21 PXF41326.1 - 4.9e-45 153.5 0.2 4.9e-45 153.5 0.2 3.3 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PXF41326.1 - 2.5e-41 141.2 0.5 2.5e-41 141.2 0.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PXF41326.1 - 2.1e-18 66.2 0.0 4.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF41326.1 - 3.6e-18 66.6 0.1 8e-17 62.2 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PXF41326.1 - 6.8e-17 60.9 0.0 1.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PXF41326.1 - 3.7e-05 23.6 0.2 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SAND PF01342.21 PXF41326.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 SAND domain SAC3_GANP PF03399.16 PXF41327.1 - 1.2e-21 77.4 3.1 5.4e-20 72.0 3.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PXF41327.1 - 0.00027 20.9 0.1 0.0012 18.8 0.1 2.0 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family RtcB PF01139.17 PXF41328.1 - 1.8e-150 501.7 0.4 2.1e-150 501.5 0.4 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB DUF3450 PF11932.8 PXF41329.1 - 4.3 6.6 10.0 0.43 9.8 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) OMPdecase PF00215.24 PXF41330.1 - 5.1e-67 225.8 0.1 7.4e-67 225.2 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 PXF41330.1 - 2.8e-08 33.5 0.0 6.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase_Tyr PF07714.17 PXF41331.1 - 1.7e-56 191.4 0.0 1.1e-54 185.5 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PXF41331.1 - 2.2e-54 184.6 0.0 1.7e-52 178.4 0.0 3.1 3 1 1 4 4 4 1 Protein kinase domain ANTH PF07651.16 PXF41331.1 - 0.00031 19.8 0.0 0.00069 18.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain Pkinase_fungal PF17667.1 PXF41331.1 - 0.0014 17.5 4.4 0.0034 16.2 0.1 2.8 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 PXF41331.1 - 0.043 12.8 0.4 0.11 11.4 0.4 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Rxt3 PF08642.10 PXF41331.1 - 0.46 11.3 2.1 2 9.2 2.1 2.0 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Med19 PF10278.9 PXF41331.1 - 0.78 9.6 12.4 1.6 8.6 12.4 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PPL5 PF18168.1 PXF41331.1 - 1.5 8.0 5.9 3.2 7.0 5.9 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 PXF41331.1 - 1.6 8.8 11.7 3.3 7.8 11.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2828 PF11443.8 PXF41331.1 - 1.8 6.6 6.2 3.1 5.8 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIIBC-GUT_N PF03612.14 PXF41331.1 - 2.4 7.9 4.4 7.2 6.3 4.4 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 PXF41331.1 - 4.2 7.1 17.0 0.46 10.3 7.1 2.7 2 1 1 3 3 3 0 Ryanodine Receptor TM 4-6 Eapp_C PF10238.9 PXF41331.1 - 5.3 7.1 11.2 1.6 8.8 4.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein NARP1 PF12569.8 PXF41331.1 - 9.6 5.0 13.9 15 4.3 13.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_1 PF00561.20 PXF41332.1 - 1.5e-27 96.9 0.2 6.6e-27 94.8 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF41332.1 - 8.6e-13 48.1 0.0 6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF41332.1 - 4.7e-09 37.2 0.0 7.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 PXF41332.1 - 0.00078 18.2 0.0 0.0016 17.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 PXF41332.1 - 0.016 14.1 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_5 PF12695.7 PXF41332.1 - 0.097 12.4 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPT PF03151.16 PXF41333.1 - 3.4e-15 56.2 12.5 6.3e-15 55.3 12.5 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF41333.1 - 0.00042 20.5 37.5 0.33 11.1 14.1 3.8 2 2 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 PXF41333.1 - 0.041 13.1 14.8 0.32 10.1 1.7 2.2 2 0 0 2 2 2 0 UAA transporter family MoeA_N PF03453.17 PXF41335.1 - 3.1e-41 140.8 1.3 4.5e-41 140.2 0.7 1.6 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 PXF41335.1 - 2.2e-23 82.5 0.0 3.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 PXF41335.1 - 7.4e-16 58.1 0.0 1.8e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Bap31_Bap29_C PF18035.1 PXF41336.1 - 0.023 14.7 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5069 PF16798.5 PXF41336.1 - 0.18 12.0 2.4 0.13 12.5 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Dopey_N PF04118.14 PXF41338.1 - 8.5e-77 258.3 0.0 1.6e-75 254.1 0.0 2.5 3 0 0 3 3 3 1 Dopey, N-terminal PolyA_pol_RNAbd PF12627.7 PXF41338.1 - 0.042 13.6 0.0 0.83 9.5 0.0 2.6 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Glyco_tran_WecB PF03808.13 PXF41338.1 - 0.085 12.8 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NADH-u_ox-rdase PF10785.9 PXF41339.1 - 7.9e-21 74.5 0.2 9.4e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Peptidase_C69 PF03577.15 PXF41340.1 - 8e-40 137.0 1.1 1.4e-39 136.2 1.1 1.3 1 1 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 PXF41340.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage Head-Tail Attachment Hexapep PF00132.24 PXF41342.1 - 1.1e-10 40.8 8.6 0.01 15.5 0.4 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PXF41342.1 - 0.026 14.3 10.8 5.8 6.8 0.2 4.3 3 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 PXF41344.1 - 2.8e-69 233.4 0.0 3.7e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41344.1 - 7.1e-38 130.4 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF41344.1 - 4.4e-09 36.1 0.0 1.4e-08 34.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF41344.1 - 2.9e-05 23.5 0.0 5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF41344.1 - 4.1e-05 23.6 0.5 0.028 14.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF41344.1 - 0.0056 16.3 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PXF41344.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PXF41344.1 - 0.052 12.5 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 PXF41344.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Branch PF02485.21 PXF41345.1 - 3.9e-32 111.7 0.0 5.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme C1-set PF07654.15 PXF41345.1 - 0.012 16.0 0.1 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin C1-set domain AMP-binding PF00501.28 PXF41346.1 - 4.3e-87 292.4 0.0 5.3e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 PXF41346.1 - 0.031 14.3 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Bromodomain PF00439.25 PXF41347.1 - 2.3e-08 34.0 0.0 2.4e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Bromodomain Phage_term_sma PF07141.11 PXF41354.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit DEAD PF00270.29 PXF41356.1 - 5.7e-12 45.8 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF41356.1 - 0.00024 21.4 0.0 0.00066 20.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TetR_C_30 PF17939.1 PXF41356.1 - 0.1 12.9 0.7 1.5 9.0 0.1 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain zinc_ribbon_6 PF14599.6 PXF41357.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon NHase_beta PF02211.15 PXF41358.1 - 0.043 13.8 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Nitrile hydratase beta subunit RAMP4 PF06624.12 PXF41369.1 - 5e-16 58.5 0.0 6.1e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Epimerase PF01370.21 PXF41371.1 - 1e-05 25.1 0.0 2.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF41371.1 - 5.4e-05 22.3 0.0 8.2e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2499 PF10693.9 PXF41372.1 - 5.7e-38 129.1 4.0 1.6e-37 127.6 4.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 PXF41372.1 - 4.6e-37 125.9 1.1 8.9e-37 125.0 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Cyt_c_ox_IV PF12270.8 PXF41372.1 - 0.27 11.4 3.2 1 9.5 1.8 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV Hydrolase_6 PF13344.6 PXF41373.1 - 1.7e-14 53.7 0.0 1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF41373.1 - 1.5e-09 37.8 0.1 4e-09 36.4 0.1 1.8 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PXF41373.1 - 6.5e-07 29.6 0.0 0.004 17.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF41373.1 - 7.1e-06 26.5 0.1 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF41373.1 - 0.025 15.0 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_38N PF01074.22 PXF41373.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain DSHCT PF08148.12 PXF41374.1 - 1.8e-39 135.0 0.1 3.8e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PXF41374.1 - 1.2e-14 54.4 0.0 2.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF41374.1 - 4.4e-08 33.5 0.2 4.8e-07 30.1 0.2 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF41374.1 - 2.4e-05 24.4 0.0 5.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 PXF41374.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain JmjN PF02375.17 PXF41375.1 - 0.043 13.8 0.8 0.088 12.8 0.8 1.5 1 0 0 1 1 1 0 jmjN domain ANAPC4_WD40 PF12894.7 PXF41376.1 - 5.2e-05 23.5 0.2 0.12 12.6 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 PXF41376.1 - 0.00011 22.0 1.2 0.041 13.8 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 PXF41376.1 - 0.00063 20.5 1.2 0.0066 17.3 0.2 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Kelch_6 PF13964.6 PXF41376.1 - 0.00079 19.6 0.1 0.45 10.9 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Ge1_WD40 PF16529.5 PXF41376.1 - 0.0018 17.3 1.8 1.1 8.1 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 PXF41376.1 - 0.074 11.0 0.1 2.1 6.3 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Kelch_4 PF13418.6 PXF41376.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Cellulase PF00150.18 PXF41377.1 - 7.4e-39 133.9 0.4 1.2e-38 133.2 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4918 PF16265.5 PXF41378.1 - 4.8e-09 36.1 0.0 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4918) UDG PF03167.19 PXF41378.1 - 8.4e-07 29.1 0.0 1.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily UMPH-1 PF05822.12 PXF41378.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) ATG16 PF08614.11 PXF41379.1 - 0.0052 17.0 1.3 0.0052 17.0 1.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 PXF41379.1 - 0.012 15.8 0.8 0.014 15.6 0.8 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 PXF41379.1 - 0.013 14.4 1.6 0.013 14.4 1.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 PXF41379.1 - 0.016 15.2 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein Bap31_Bap29_C PF18035.1 PXF41379.1 - 0.039 13.9 5.3 0.046 13.7 5.3 1.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Transketolase_N PF00456.21 PXF41380.1 - 4.3e-145 482.9 0.0 5.7e-145 482.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PXF41380.1 - 2.4e-35 121.8 0.0 3.7e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PXF41380.1 - 1.3e-08 34.7 0.0 3e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 PXF41380.1 - 1.6e-05 24.2 0.9 1.9e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase POR PF01558.18 PXF41380.1 - 0.024 14.7 0.0 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 PXF41380.1 - 0.045 13.5 0.2 0.18 11.6 0.2 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 PXF41380.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component WD40 PF00400.32 PXF41381.1 - 1.9e-09 38.0 3.1 0.027 15.3 0.0 4.9 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41381.1 - 5.9e-08 32.9 0.0 0.015 15.5 0.0 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 PXF41381.1 - 0.03 13.9 0.5 0.094 12.3 0.5 1.8 1 0 0 1 1 1 0 Trimerisation motif Shugoshin_N PF07558.11 PXF41381.1 - 0.14 12.0 0.4 0.35 10.8 0.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region FAM76 PF16046.5 PXF41381.1 - 0.6 9.4 2.3 0.99 8.7 2.3 1.3 1 0 0 1 1 1 0 FAM76 protein Rep_fac-A_3 PF08661.11 PXF41382.1 - 3.2e-05 24.2 0.0 3.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Cation_ATPase_C PF00689.21 PXF41383.1 - 3.3e-45 154.0 0.1 3.3e-45 154.0 0.1 2.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PXF41383.1 - 1.2e-44 152.0 2.7 1.2e-44 152.0 2.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 PXF41383.1 - 2.1e-20 72.2 0.0 4.6e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PXF41383.1 - 1.3e-19 70.0 0.2 2.8e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF41383.1 - 3.9e-18 66.5 0.2 7.4e-10 39.5 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF41383.1 - 5.6e-06 26.3 1.9 0.0046 16.7 1.5 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1798 PF08807.10 PXF41385.1 - 0.1 12.7 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Nucleoporin_FG2 PF15967.5 PXF41385.1 - 5 5.5 29.7 3.5 6.1 0.0 3.1 2 1 0 2 2 2 0 Nucleoporin FG repeated region Methyltrn_RNA_3 PF02598.17 PXF41386.1 - 1.8e-87 293.5 0.0 2.1e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase DUF2808 PF10989.8 PXF41386.1 - 0.011 15.8 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) SpoU_methylase PF00588.19 PXF41386.1 - 0.079 13.1 0.0 7.5 6.7 0.0 2.4 2 1 1 3 3 3 0 SpoU rRNA Methylase family DHHC PF01529.20 PXF41387.1 - 7.3e-37 126.5 5.7 7.3e-37 126.5 5.7 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase ABC_export PF16962.5 PXF41387.1 - 3.4 6.0 8.3 1.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Putative ABC exporter Phos_pyr_kin PF08543.12 PXF41388.1 - 6.3e-96 320.5 0.0 7.2e-96 320.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 PXF41388.1 - 3.8e-08 33.0 0.0 1.8e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 PXF41388.1 - 4.8e-07 29.5 0.3 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate kinase HK PF02110.15 PXF41388.1 - 0.008 15.6 0.6 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Peptidase_S9 PF00326.21 PXF41390.1 - 0.00069 19.2 0.1 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chorismate_synt PF01264.21 PXF41391.1 - 5.6e-139 462.4 0.1 6.3e-139 462.2 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3619 PF12279.8 PXF41392.1 - 0.015 15.6 0.6 0.022 15.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF2254 PF10011.9 PXF41392.1 - 0.016 14.1 0.2 0.019 13.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF445 PF04286.12 PXF41392.1 - 0.022 14.6 0.4 0.027 14.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Thioredoxin PF00085.20 PXF41392.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DraK_HK_N PF18092.1 PXF41392.1 - 0.088 13.2 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain EF-1_beta_acid PF10587.9 PXF41392.1 - 0.096 13.2 1.8 0.24 11.9 1.8 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region S1 PF00575.23 PXF41393.1 - 2.7e-37 126.9 4.8 4.3e-17 62.2 1.6 3.2 3 0 0 3 3 3 3 S1 RNA binding domain FAD_binding_8 PF08022.12 PXF41394.1 - 1.4e-18 67.0 0.0 4.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 PXF41394.1 - 1.3e-16 61.1 0.3 2.8e-09 37.3 0.0 3.7 3 1 0 3 3 3 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF41394.1 - 3e-07 30.6 4.8 1.3e-06 28.6 4.8 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 PXF41394.1 - 0.021 15.5 0.2 12 6.6 0.0 2.7 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain adh_short PF00106.25 PXF41395.1 - 2.9e-46 157.4 0.0 3.6e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF41395.1 - 5.7e-34 117.7 0.1 7e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF41395.1 - 9.5e-12 45.2 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF41395.1 - 5.1e-05 22.8 0.1 0.00015 21.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 PXF41395.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WLM PF08325.10 PXF41396.1 - 6.9e-52 176.3 0.1 9.3e-51 172.6 0.0 1.9 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 PXF41396.1 - 0.017 15.1 0.3 0.034 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 SVIP PF15811.5 PXF41396.1 - 0.069 13.6 1.6 20 5.7 0.0 3.2 3 0 0 3 3 3 0 Small VCP/p97-interacting protein F-box PF00646.33 PXF41397.1 - 0.31 11.0 3.5 4.1 7.4 1.4 3.2 3 0 0 3 3 3 0 F-box domain Cpn60_TCP1 PF00118.24 PXF41398.1 - 1.3e-91 307.8 7.2 1.7e-91 307.3 7.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SH3_9 PF14604.6 PXF41399.1 - 7.6e-13 48.1 0.1 1.2e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PXF41399.1 - 5.2e-12 45.2 0.0 8.7e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PXF41399.1 - 1e-09 37.9 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UMP1 PF05348.11 PXF41400.1 - 8.4e-21 74.4 0.1 9.7e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 HAD PF12710.7 PXF41401.1 - 1.2e-19 71.5 0.1 2.4e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF41401.1 - 2.4e-15 57.4 0.2 5.6e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 PXF41401.1 - 6e-12 45.4 1.3 1.1e-11 44.5 0.4 2.0 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 PXF41401.1 - 1.9e-11 44.2 1.5 1.4e-10 41.3 0.2 2.7 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PXF41401.1 - 0.0002 21.5 0.1 0.0013 18.8 0.1 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PXF41401.1 - 0.00024 20.6 0.0 0.063 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 PXF41401.1 - 0.02 14.3 0.1 0.04 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF705) NIF PF03031.18 PXF41401.1 - 0.061 13.1 0.3 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase DUF1776 PF08643.10 PXF41401.1 - 0.092 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Hydrolase_6 PF13344.6 PXF41402.1 - 5.7e-23 80.9 0.0 9.5e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF41402.1 - 4.1e-12 46.0 0.0 8.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF493 PF04359.14 PXF41403.1 - 1.9e-06 28.3 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF493) CIAPIN1 PF05093.13 PXF41404.1 - 6.7e-24 84.3 15.2 4.1e-18 65.7 4.1 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MIF4G PF02854.19 PXF41405.1 - 2.7e-05 23.9 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 PXF41405.1 - 7.6e-05 22.7 0.0 0.00084 19.3 0.0 2.4 3 0 0 3 3 3 1 MA3 domain W2 PF02020.18 PXF41405.1 - 0.0076 16.4 0.7 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PsbQ PF05757.11 PXF41405.1 - 0.024 14.4 0.2 0.081 12.6 0.1 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Peptidase_A25 PF03418.14 PXF41405.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Germination protease CIAPIN1 PF05093.13 PXF41406.1 - 4e-07 30.5 0.6 9.2e-07 29.3 0.6 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltrans_RNA PF04452.14 PXF41407.1 - 6.1e-26 91.1 0.1 6.9e-26 91.0 0.1 1.1 1 0 0 1 1 1 1 RNA methyltransferase CIAPIN1 PF05093.13 PXF41408.1 - 6.7e-24 84.3 15.2 4.1e-18 65.7 4.1 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltrans_RNA PF04452.14 PXF41409.1 - 7.2e-45 153.1 0.1 8.8e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 RNA methyltransferase MIF4G PF02854.19 PXF41410.1 - 3.2e-32 111.9 5.0 7.5e-32 110.7 5.0 1.7 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 PXF41410.1 - 0.00011 22.2 0.4 0.0024 17.8 0.0 2.8 3 0 0 3 3 3 1 MA3 domain W2 PF02020.18 PXF41410.1 - 0.00024 21.2 0.1 0.048 13.8 0.0 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PsbQ PF05757.11 PXF41410.1 - 0.063 13.0 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ORC_WH_C PF18137.1 PXF41410.1 - 7.3 6.7 8.3 0.32 11.0 0.6 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal vATP-synt_AC39 PF01992.16 PXF41411.1 - 9e-113 377.2 0.5 1e-112 377.0 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF3425 PF11905.8 PXF41411.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) IPP-2 PF04979.14 PXF41412.1 - 1.3e-15 58.3 0.0 2.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) G-patch_2 PF12656.7 PXF41413.1 - 0.04 14.0 0.0 0.04 14.0 0.0 2.8 3 0 0 3 3 3 0 G-patch domain ALMS_repeat PF18727.1 PXF41413.1 - 0.095 12.6 0.3 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 Alstrom syndrome repeat ORC6 PF05460.13 PXF41413.1 - 2.5 7.3 9.3 0.095 12.0 3.8 1.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) zf-LITAF-like PF10601.9 PXF41414.1 - 2.4e-07 30.9 16.0 3.1e-07 30.6 16.0 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain WD40 PF00400.32 PXF41415.1 - 1.8e-17 63.3 26.4 1.5e-05 25.7 0.1 9.1 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41415.1 - 4e-16 59.1 3.0 0.0003 21.0 0.0 6.1 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF41415.1 - 0.012 14.6 0.8 5.9 5.8 0.0 4.1 3 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 PXF41415.1 - 0.069 11.5 0.0 0.89 7.8 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz bZIP_1 PF00170.21 PXF41416.1 - 1.9e-08 34.3 13.6 1.9e-08 34.3 13.6 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF41416.1 - 0.00066 19.7 18.8 0.0011 19.0 17.3 2.2 1 1 1 2 2 2 1 Basic region leucine zipper PilJ PF13675.6 PXF41416.1 - 0.22 11.5 9.7 0.091 12.8 4.8 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG5 PF10392.9 PXF41416.1 - 0.38 10.9 6.6 0.73 10.0 6.6 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Noelin-1 PF12308.8 PXF41416.1 - 0.46 10.5 5.2 1.8 8.6 5.1 2.1 1 1 0 1 1 1 0 Neurogenesis glycoprotein FAM76 PF16046.5 PXF41416.1 - 2.2 7.6 11.3 3.3 7.0 11.3 1.2 1 0 0 1 1 1 0 FAM76 protein CdvA PF18822.1 PXF41417.1 - 0.00092 19.0 0.3 0.0022 17.8 0.3 1.6 1 1 0 1 1 1 1 CdvA-like coiled-coil domain DUF4164 PF13747.6 PXF41417.1 - 0.038 14.3 0.5 0.047 14.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TSKS PF15358.6 PXF41417.1 - 0.044 12.2 0.1 0.052 11.9 0.1 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate WD40 PF00400.32 PXF41419.1 - 1.6e-07 31.9 2.9 0.033 15.1 0.2 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 PXF41419.1 - 0.0015 17.1 0.0 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 PXF41419.1 - 0.018 15.5 0.3 7.2 7.2 0.1 3.2 2 0 0 2 2 2 0 PQQ-like domain Ctr PF04145.15 PXF41420.1 - 6.6e-12 46.3 13.9 2.2e-10 41.3 7.0 2.2 1 1 1 2 2 2 2 Ctr copper transporter family DUF3054 PF11255.8 PXF41420.1 - 0.067 13.7 0.2 0.067 13.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3054) DUF2897 PF11446.8 PXF41420.1 - 0.068 13.1 0.9 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) VirB3 PF05101.13 PXF41420.1 - 0.16 12.2 7.4 0.049 13.9 3.6 1.9 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF5337 PF17272.2 PXF41420.1 - 0.16 11.8 3.2 0.39 10.6 3.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Bac_export_2 PF01312.19 PXF41420.1 - 0.34 10.1 2.2 0.45 9.7 2.2 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family LapA_dom PF06305.11 PXF41420.1 - 1.1 9.1 7.3 8.7 6.2 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-U1 PF06220.12 PXF41421.1 - 1.9e-14 53.1 7.7 3e-14 52.5 7.7 1.3 1 0 0 1 1 1 1 U1 zinc finger tRNA-synt_2b PF00587.25 PXF41422.1 - 4.9e-33 114.6 0.0 1.1e-32 113.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PXF41422.1 - 9.4e-19 67.6 5.7 1.9e-18 66.6 5.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-K PF11802.8 PXF41422.1 - 0.012 15.2 2.9 0.016 14.8 2.3 1.5 2 0 0 2 2 2 0 Centromere-associated protein K APG6_N PF17675.1 PXF41422.1 - 0.13 12.8 3.9 0.27 11.7 3.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Mad3_BUB1_I PF08311.12 PXF41423.1 - 1.2e-24 86.7 0.5 2.9e-24 85.4 0.5 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 PXF41423.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 PXF41423.1 - 0.015 15.4 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein adh_short PF00106.25 PXF41424.1 - 1.3e-39 135.7 0.1 1.6e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF41424.1 - 3.4e-31 108.6 0.0 4.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF41424.1 - 1.1e-06 28.7 0.1 1.7e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 PXF41425.1 - 2.8e-32 110.2 42.6 8.6e-06 26.4 0.0 11.5 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41425.1 - 1.8e-14 53.8 8.3 0.013 15.8 0.0 8.2 2 2 6 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF41425.1 - 8.3e-10 38.3 0.0 2.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 PXF41425.1 - 2.5e-07 30.0 1.3 1.3 7.9 0.0 6.4 5 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF41425.1 - 0.0084 14.8 0.1 0.25 9.9 0.0 3.3 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PXF41425.1 - 0.009 14.8 0.0 0.55 8.9 0.0 3.3 4 1 0 4 4 4 1 Nup133 N terminal like PQQ PF01011.21 PXF41425.1 - 0.011 15.6 0.1 83 3.4 0.0 4.5 4 0 0 4 4 4 0 PQQ enzyme repeat WASH_WAHD PF11945.8 PXF41425.1 - 0.018 14.6 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex PD40 PF07676.12 PXF41425.1 - 0.087 12.8 2.3 53 3.9 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat APAF1_C PF17908.1 PXF41425.1 - 0.099 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 APAF-1 helical domain UAA PF08449.11 PXF41426.1 - 8.8e-62 209.0 17.9 1e-61 208.8 17.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF41426.1 - 0.00012 22.3 27.1 0.0057 16.8 2.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 PXF41426.1 - 0.00021 20.3 4.1 0.00021 20.3 4.1 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF1774 PF08611.10 PXF41426.1 - 0.005 17.1 0.2 0.023 15.0 0.2 2.1 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1774) MGTL PF17059.5 PXF41426.1 - 1.7 8.5 3.4 3.7 7.5 3.4 1.5 1 0 0 1 1 1 0 MgtA leader peptide zf-RING_2 PF13639.6 PXF41427.1 - 4.9e-09 36.4 9.6 4.9e-09 36.4 9.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 PXF41427.1 - 5.8e-08 32.3 6.5 5.8e-08 32.3 6.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PXF41427.1 - 1.9e-05 24.4 8.8 4.2e-05 23.3 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF41427.1 - 2.9e-05 23.8 9.7 2.9e-05 23.8 9.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF41427.1 - 0.0001 22.5 16.6 0.00062 20.0 16.6 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF41427.1 - 0.0029 17.5 7.9 0.008 16.1 7.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF41427.1 - 0.003 17.5 5.3 0.0082 16.2 5.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger SfLAP PF11139.8 PXF41427.1 - 0.03 13.8 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein zf-ANAPC11 PF12861.7 PXF41427.1 - 0.18 11.9 9.6 0.62 10.2 9.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PXF41427.1 - 1.2 8.8 11.5 5.2 6.8 11.6 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Thioredoxin_16 PF18569.1 PXF41428.1 - 0.099 12.8 0.7 0.26 11.4 0.7 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain PAP_central PF04928.17 PXF41429.1 - 7.3e-94 313.4 0.0 1e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PXF41429.1 - 5.1e-23 81.5 0.2 2e-15 56.9 0.0 2.9 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PXF41429.1 - 2e-07 31.2 0.0 4.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 PXF41429.1 - 0.12 12.2 0.1 0.75 9.6 0.1 2.1 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain HEAT_2 PF13646.6 PXF41430.1 - 1.1e-12 48.2 0.1 0.00046 20.5 0.0 2.9 1 1 3 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 PXF41430.1 - 8.9e-05 22.8 2.1 2.6 9.0 0.0 4.1 3 1 0 3 3 3 2 PBS lyase HEAT-like repeat HEAT PF02985.22 PXF41430.1 - 0.0036 17.4 0.6 13 6.3 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat DUF4042 PF13251.6 PXF41430.1 - 0.1 12.3 0.3 3.1 7.5 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) WD40 PF00400.32 PXF41431.1 - 6.1e-30 102.8 26.9 1.2e-05 26.0 0.0 9.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41431.1 - 1.8e-10 41.0 7.1 1.4 9.3 0.1 8.0 3 3 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF41431.1 - 1.2e-09 37.8 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 PXF41431.1 - 8.5e-05 21.7 1.2 0.65 8.9 0.0 4.9 4 3 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF41431.1 - 0.0077 14.9 0.3 3.5 6.1 0.0 4.2 3 1 2 5 5 5 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 PXF41431.1 - 0.023 14.7 0.1 15 5.7 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Hira PF07569.11 PXF41431.1 - 0.2 11.3 0.2 36 4.0 0.0 4.3 4 1 1 5 5 5 0 TUP1-like enhancer of split Exostosin PF03016.15 PXF41432.1 - 1.5e-58 198.4 0.6 1.8e-58 198.1 0.6 1.1 1 0 0 1 1 1 1 Exostosin family Sec16_C PF12931.7 PXF41433.1 - 5.7e-25 88.6 0.0 1e-24 87.7 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 PXF41433.1 - 0.00097 19.7 0.0 0.0038 17.8 0.0 2.2 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Rad10 PF03834.14 PXF41434.1 - 1.1e-38 131.8 0.0 1.5e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 PXF41434.1 - 0.00014 22.4 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 PXF41434.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 PXF41434.1 - 0.012 15.6 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HRDC PF00570.23 PXF41434.1 - 0.034 14.1 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 HRDC domain Methyltransf_8 PF05148.15 PXF41434.1 - 0.042 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Hist_deacetyl PF00850.19 PXF41435.1 - 1.5e-82 277.5 0.0 2.1e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain TLD PF07534.16 PXF41436.1 - 6e-09 36.2 0.0 8.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 TLD DUF2694 PF10904.8 PXF41437.1 - 0.24 11.5 2.2 0.42 10.7 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2694) SRP-alpha_N PF04086.13 PXF41437.1 - 0.51 10.2 9.8 0.7 9.8 9.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RHH_1 PF01402.21 PXF41438.1 - 0.016 15.1 2.3 0.016 15.1 2.3 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family ArAE_2_N PF10337.9 PXF41438.1 - 0.036 13.1 5.9 0.059 12.4 5.9 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal 3HCDH PF00725.22 PXF41438.1 - 0.2 12.3 0.3 0.63 10.7 0.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Hamartin PF04388.12 PXF41438.1 - 0.53 8.9 8.2 0.57 8.8 8.2 1.0 1 0 0 1 1 1 0 Hamartin protein TPR_MLP1_2 PF07926.12 PXF41438.1 - 0.78 9.8 25.9 0.93 9.6 18.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_M3 PF01432.20 PXF41439.1 - 8.9e-23 81.3 0.1 1.8e-22 80.3 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 PXF41439.1 - 1.8e-09 37.7 0.1 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 Oligopeptidase F Peptidase_M78 PF06114.13 PXF41439.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M48 PF01435.18 PXF41439.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M10 PF00413.24 PXF41439.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Matrixin Rhodanese PF00581.20 PXF41440.1 - 2e-10 41.1 0.0 2.5e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain PfkB PF00294.24 PXF41441.1 - 7.3e-46 156.8 7.2 1.2e-45 156.2 7.2 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 PXF41441.1 - 0.0024 17.4 0.3 0.0046 16.5 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate kinase zf_CCCH_4 PF18345.1 PXF41441.1 - 1.4 9.1 8.4 1.6 8.9 5.4 2.2 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 PXF41441.1 - 6.8 6.7 8.9 1.3 9.0 5.1 1.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Methyltransf_21 PF05050.12 PXF41442.1 - 1.2e-11 44.9 0.0 1.8e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain LRV_FeS PF05484.11 PXF41442.1 - 0.12 12.4 0.9 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 LRV protein FeS4 cluster HAUS6_N PF14661.6 PXF41445.1 - 2.1e-19 70.0 1.9 6.1e-18 65.2 0.0 2.9 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Uso1_p115_C PF04871.13 PXF41445.1 - 0.27 11.6 0.0 0.27 11.6 0.0 3.8 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region ParA PF10609.9 PXF41446.1 - 6.2e-98 327.1 0.1 7.6e-98 326.8 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PXF41446.1 - 3.6e-15 56.1 0.0 1.8e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PXF41446.1 - 3.7e-10 40.0 0.2 3e-09 37.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 PXF41446.1 - 8.5e-10 38.3 0.4 2.3e-08 33.6 0.0 2.4 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 PXF41446.1 - 7.2e-07 28.8 0.0 1.6e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 PXF41446.1 - 2e-05 24.2 0.1 0.00067 19.2 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 PXF41446.1 - 0.00014 21.0 0.1 0.00021 20.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 PXF41446.1 - 0.00052 19.6 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PXF41446.1 - 0.0015 18.5 0.1 0.0031 17.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_26 PF13500.6 PXF41446.1 - 0.0026 17.6 0.9 0.39 10.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain CBP_BcsQ PF06564.12 PXF41446.1 - 0.0031 17.0 0.3 0.016 14.7 0.3 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 PXF41446.1 - 0.0031 17.4 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase SRP54 PF00448.22 PXF41446.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 PXF41446.1 - 0.036 13.8 0.0 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 PXF41446.1 - 0.095 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain VirC1 PF07015.11 PXF41446.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.6 PXF41446.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 PXF41446.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 PXF41446.1 - 0.22 11.5 0.0 0.73 9.8 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UQ_con PF00179.26 PXF41447.1 - 4.9e-44 149.4 0.0 5.6e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PXF41447.1 - 0.0007 19.5 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 PXF41447.1 - 0.013 15.8 0.0 0.019 15.2 0.0 1.3 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 PXF41448.1 - 3.9e-87 292.3 0.4 7.4e-87 291.4 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PXF41448.1 - 5.6e-19 68.5 0.1 7.8e-17 61.6 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding TEX12 PF15219.6 PXF41448.1 - 0.0042 17.4 2.0 0.012 16.0 1.6 1.9 1 1 0 1 1 1 1 Testis-expressed 12 ATP-synt_E PF05680.12 PXF41448.1 - 2.9 8.3 8.4 0.2 12.0 1.8 2.4 2 0 0 2 2 2 0 ATP synthase E chain ParA PF10609.9 PXF41449.1 - 1.6e-85 286.5 0.2 2.2e-85 286.1 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 PXF41449.1 - 3.5e-15 56.4 0.0 7.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) FeS_assembly_P PF01883.19 PXF41449.1 - 4.2e-13 49.3 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 PXF41449.1 - 1.7e-12 47.5 0.0 3.8e-12 46.4 0.0 1.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PXF41449.1 - 2.7e-11 43.7 1.1 1.2e-08 35.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 PXF41449.1 - 1.4e-10 40.9 0.0 3.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PXF41449.1 - 0.00013 21.3 0.5 0.016 14.4 0.3 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 PXF41449.1 - 0.0004 19.9 0.4 0.078 12.5 0.3 2.4 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 PXF41449.1 - 0.0021 17.6 0.1 0.0071 15.8 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 PXF41449.1 - 0.005 16.2 0.1 0.0081 15.5 0.1 1.3 1 0 0 1 1 1 1 VirC1 protein FTHFS PF01268.19 PXF41449.1 - 0.072 11.3 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase MRP-S27 PF10037.9 PXF41450.1 - 0.021 13.7 4.5 0.03 13.2 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 V_ATPase_I PF01496.19 PXF41450.1 - 0.026 12.5 0.1 0.034 12.1 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2207 PF09972.9 PXF41450.1 - 0.039 12.7 0.6 0.18 10.5 0.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4375 PF14300.6 PXF41450.1 - 0.056 13.7 1.8 0.084 13.1 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) TryThrA_C PF12319.8 PXF41450.1 - 0.091 12.2 5.6 0.14 11.7 5.6 1.2 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal HIT PF01230.23 PXF41451.1 - 3.3e-22 79.0 0.2 4.7e-22 78.6 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PXF41451.1 - 0.0001 22.7 0.1 0.00017 22.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Tic22 PF04278.12 PXF41452.1 - 8.9e-30 103.9 0.1 1.9e-17 63.5 0.0 2.9 3 0 0 3 3 3 2 Tic22-like family TPR_1 PF00515.28 PXF41452.1 - 3.6e-14 51.9 1.5 1.6e-05 24.5 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF41452.1 - 4.1e-12 45.6 0.8 5.2e-07 29.2 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 PXF41452.1 - 3.2e-09 36.2 2.6 4.1e-05 23.4 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF41452.1 - 0.0003 21.4 0.1 0.02 15.7 0.0 5.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF41452.1 - 0.00084 19.2 0.2 0.97 9.6 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF41452.1 - 0.00087 19.3 1.0 0.018 15.2 0.5 4.1 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF41452.1 - 0.0047 17.1 4.8 1.4 9.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF41452.1 - 0.012 16.2 0.0 0.012 16.2 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PXF41452.1 - 0.02 15.2 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF41452.1 - 0.13 12.8 0.1 0.13 12.8 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat APH PF01636.23 PXF41454.1 - 9.7e-07 29.0 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF41454.1 - 0.022 14.1 0.1 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Kinesin PF00225.23 PXF41455.1 - 1.7e-112 375.7 2.0 2.1e-112 375.3 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF41455.1 - 1.9e-24 86.3 0.0 1.2e-23 83.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Baculo_PEP_C PF04513.12 PXF41455.1 - 0.00011 22.2 32.8 0.14 12.2 1.7 5.3 4 2 0 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus BMFP PF04380.13 PXF41455.1 - 0.26 11.8 12.8 2.5 8.7 0.4 5.0 4 1 1 5 5 5 0 Membrane fusogenic activity DUF948 PF06103.11 PXF41455.1 - 0.56 10.5 29.2 0.59 10.4 0.0 7.1 5 3 2 8 8 8 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 PXF41455.1 - 2.3 8.2 13.5 8.8 6.3 0.1 4.7 4 0 0 4 4 4 0 Apolipoprotein O DUF848 PF05852.11 PXF41455.1 - 5.2 7.2 43.4 1.1 9.4 4.2 5.6 3 2 1 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TBD PF12845.7 PXF41455.1 - 7.2 6.6 8.4 9.6 6.2 0.5 3.1 3 0 0 3 3 3 0 TBD domain FYVE_2 PF02318.16 PXF41455.1 - 8.5 6.6 14.1 1.2 9.4 0.3 3.7 4 0 0 4 4 4 0 FYVE-type zinc finger PUL PF08324.11 PXF41456.1 - 2.8e-37 128.5 0.3 4.5e-37 127.8 0.3 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 PXF41456.1 - 4.7e-34 117.1 0.1 9.2e-34 116.1 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 PXF41456.1 - 2.5e-30 104.1 22.2 9.8e-06 26.2 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 PXF41456.1 - 0.0012 17.6 6.5 0.047 12.3 0.1 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PXF41456.1 - 0.0089 16.3 0.2 0.092 13.1 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 PXF41457.1 - 4.9e-13 49.2 7.5 7.8e-13 48.5 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PXF41457.1 - 1.2e-11 44.7 7.0 2.1e-11 43.9 7.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF41457.1 - 4.4e-10 39.2 7.7 7.6e-10 38.5 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF41457.1 - 6e-08 32.3 5.6 6e-08 32.3 5.6 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PXF41457.1 - 4.5e-07 29.8 1.2 4.5e-07 29.8 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF41457.1 - 9.5e-07 28.6 6.6 1.5e-06 28.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF41457.1 - 3.8e-06 26.9 5.3 8.5e-06 25.7 5.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF41457.1 - 3.8e-05 23.5 9.0 6.6e-05 22.8 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF41457.1 - 6.6e-05 22.7 8.5 9.5e-05 22.2 8.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 PXF41457.1 - 0.004 16.9 4.7 0.0076 16.0 4.7 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_16 PF17034.5 PXF41457.1 - 0.0072 16.5 3.9 0.01 16.0 3.9 1.2 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 PXF41457.1 - 0.01 15.4 10.7 0.016 14.8 10.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 PXF41457.1 - 0.011 15.9 4.6 0.023 14.9 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 PXF41457.1 - 0.15 12.2 8.7 0.35 11.0 8.7 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 PXF41457.1 - 0.34 10.8 10.9 0.95 9.4 10.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 PXF41457.1 - 0.44 10.9 8.2 0.8 10.1 7.9 1.6 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 PXF41457.1 - 4.4 7.5 11.4 23 5.2 11.0 2.1 1 1 1 2 2 2 0 RING-variant domain FANCL_C PF11793.8 PXF41457.1 - 9.7 6.5 9.8 33 4.8 9.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Macoilin PF09726.9 PXF41458.1 - 7.7 4.9 17.4 10 4.5 17.4 1.1 1 0 0 1 1 1 0 Macoilin family HMGL-like PF00682.19 PXF41459.1 - 2.1e-43 148.8 0.0 3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 PXF41459.1 - 4.7e-18 65.4 0.0 9.1e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Mito_carr PF00153.27 PXF41460.1 - 1.9e-59 197.6 6.0 1.2e-19 70.0 0.6 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Urocanase PF01175.18 PXF41460.1 - 0.014 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Serine_protease PF18405.1 PXF41460.1 - 0.5 9.5 2.9 2.3 7.3 0.0 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease NDK PF00334.19 PXF41461.1 - 3.7e-49 166.2 0.0 4.2e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 PXF41461.1 - 0.034 14.7 0.1 0.062 13.8 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ DUF21 PF01595.20 PXF41462.1 - 6.6e-35 120.4 3.5 1.1e-34 119.7 3.5 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PXF41462.1 - 0.00053 20.4 0.5 0.02 15.3 0.1 2.7 2 0 0 2 2 2 1 CBS domain Mannosyl_trans3 PF11051.8 PXF41462.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative PatG_C PF18065.1 PXF41463.1 - 0.79 9.7 3.5 3.2 7.8 0.5 2.4 1 1 1 2 2 2 0 PatG C-terminal LMBR1 PF04791.16 PXF41463.1 - 2.7 6.8 9.6 4 6.2 9.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM76 PF16046.5 PXF41463.1 - 5.2 6.3 12.3 8 5.7 12.3 1.2 1 0 0 1 1 1 0 FAM76 protein OB_NTP_bind PF07717.16 PXF41464.1 - 8.2e-20 71.0 0.0 2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PXF41464.1 - 6.5e-17 61.8 0.4 1.4e-14 54.3 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 PXF41464.1 - 2.7e-13 50.1 1.0 4.1e-13 49.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF41464.1 - 3.8e-13 49.7 0.0 1.2e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PXF41464.1 - 8.7e-05 22.9 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF41464.1 - 0.00035 19.7 0.0 0.00069 18.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 PXF41464.1 - 0.00049 20.4 0.4 0.0019 18.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PXF41464.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 PXF41464.1 - 0.015 15.3 0.2 0.062 13.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF41464.1 - 0.018 14.8 0.2 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 PXF41464.1 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 PXF41464.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 PXF41464.1 - 0.11 12.5 0.0 0.76 9.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF41464.1 - 0.18 12.2 0.8 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain dsRBD2 PF17842.1 PXF41464.1 - 0.3 11.3 2.9 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 SMP_LBD PF17047.5 PXF41466.1 - 2e-19 69.8 0.0 3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 PXF41466.1 - 2.4e-17 63.1 0.0 4.8e-13 49.3 0.0 2.5 2 1 0 2 2 2 2 C2 domain DNA_pol_A_exo1 PF01612.20 PXF41468.1 - 8.5e-42 142.8 0.1 1.5e-41 142.0 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 PXF41468.1 - 1.7e-05 24.7 0.0 9.7e-05 22.3 0.0 2.5 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 PXF41468.1 - 0.0023 18.6 1.6 0.0023 18.6 1.6 3.0 3 0 0 3 3 3 1 PMC2NT (NUC016) domain Pterin_bind PF00809.22 PXF41471.1 - 5.3e-27 95.0 0.0 5.9e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme zf-C2H2 PF00096.26 PXF41473.1 - 7.8e-09 35.5 17.9 0.0058 17.0 0.9 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PXF41473.1 - 1.3e-07 31.2 11.2 0.034 13.9 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PXF41473.1 - 2.7e-06 27.7 18.0 0.0055 17.5 0.9 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF41473.1 - 0.0056 16.3 4.1 1.8 8.3 0.3 3.2 2 1 1 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain DUF1677 PF07911.13 PXF41473.1 - 0.0074 16.7 0.4 0.0074 16.7 0.4 2.1 3 0 0 3 3 1 1 Protein of unknown function (DUF1677) zf-met PF12874.7 PXF41473.1 - 0.0096 16.3 10.2 12 6.5 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.15 PXF41473.1 - 0.027 14.5 14.7 0.05 13.6 1.7 3.4 1 1 2 3 3 3 0 BED zinc finger Prim_Zn_Ribbon PF08273.12 PXF41473.1 - 0.043 14.1 5.8 0.25 11.6 5.8 2.4 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2_2 PF12756.7 PXF41473.1 - 0.13 12.7 16.5 2.7 8.4 0.3 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.7 PXF41473.1 - 0.14 12.3 1.4 1.8 8.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-binding OrsD PF12013.8 PXF41473.1 - 0.22 12.0 11.1 3.3 8.2 0.2 3.7 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Di19 PF05605.12 PXF41473.1 - 0.22 11.8 6.9 3.4 8.0 0.6 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 PXF41473.1 - 0.36 10.7 2.1 32 4.5 0.0 3.6 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_7 PF15269.6 PXF41473.1 - 0.37 10.9 2.0 2.3 8.4 0.1 2.7 1 1 2 3 3 3 0 Zinc-finger zf-C2H2_jaz PF12171.8 PXF41473.1 - 0.61 10.4 6.6 7.9 6.9 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF4428 PF14471.6 PXF41473.1 - 0.66 9.9 3.3 3.3 7.7 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) Rubredoxin_2 PF18073.1 PXF41473.1 - 2 8.2 8.7 23 4.8 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Chromo PF00385.24 PXF41474.1 - 0.00011 22.0 0.1 0.00037 20.3 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PepSY PF03413.19 PXF41474.1 - 0.0044 17.6 0.2 0.011 16.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain DUF4976 PF16347.5 PXF41474.1 - 0.073 13.3 0.1 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) RecT PF03837.14 PXF41475.1 - 0.14 11.7 1.3 0.14 11.6 1.3 1.0 1 0 0 1 1 1 0 RecT family zf-C2H2 PF00096.26 PXF41477.1 - 1e-08 35.2 17.9 0.0062 16.9 0.9 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PXF41477.1 - 1.6e-07 31.0 11.2 0.037 13.8 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PXF41477.1 - 3.5e-06 27.4 18.0 0.0058 17.4 0.9 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF41477.1 - 0.0063 16.1 4.0 1.9 8.2 0.3 3.2 2 1 1 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain DUF1677 PF07911.13 PXF41477.1 - 0.0079 16.6 0.4 0.0079 16.6 0.4 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF1677) zf-met PF12874.7 PXF41477.1 - 0.012 16.0 10.2 12 6.4 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type OrsD PF12013.8 PXF41477.1 - 0.032 14.7 8.1 3.5 8.1 0.2 3.7 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 PXF41477.1 - 0.034 14.2 14.7 0.066 13.2 2.6 3.4 1 1 2 3 3 3 0 BED zinc finger Prim_Zn_Ribbon PF08273.12 PXF41477.1 - 0.054 13.8 5.8 0.27 11.5 5.8 2.2 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2H2_2 PF12756.7 PXF41477.1 - 0.16 12.3 16.6 2.9 8.3 0.3 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.7 PXF41477.1 - 0.17 12.1 1.4 2 8.6 0.3 2.5 2 0 0 2 2 2 0 Zinc-binding zf-Di19 PF05605.12 PXF41477.1 - 0.23 11.8 6.7 7.8 6.9 1.8 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 PXF41477.1 - 0.29 11.0 1.6 34 4.4 0.0 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DUF4428 PF14471.6 PXF41477.1 - 0.49 10.4 3.0 3.5 7.6 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_jaz PF12171.8 PXF41477.1 - 0.76 10.1 6.6 8.4 6.8 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Rubredoxin_2 PF18073.1 PXF41477.1 - 2.4 8.0 8.7 24 4.7 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain Radical_SAM PF04055.21 PXF41479.1 - 1.4e-14 54.8 0.0 2.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 PXF41479.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 PXF41479.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Arf PF00025.21 PXF41480.1 - 1.5e-59 200.4 0.0 1.7e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PXF41480.1 - 1.2e-08 34.7 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PXF41480.1 - 2.8e-08 33.4 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PXF41480.1 - 5.1e-08 33.2 0.0 1.1e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PXF41480.1 - 5.9e-08 32.3 0.1 4.2e-05 22.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PXF41480.1 - 6.9e-07 29.4 0.0 9.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PXF41480.1 - 0.00053 19.4 0.0 0.00055 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PXF41480.1 - 0.002 17.7 0.1 0.059 12.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PXF41480.1 - 0.03 14.1 0.0 0.096 12.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Antibiotic_NAT PF02522.14 PXF41480.1 - 0.077 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase SRR1 PF07985.12 PXF41481.1 - 8.2e-14 51.4 0.1 1.5e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 SRR1 DUF3040 PF11239.8 PXF41482.1 - 0.0021 18.3 0.1 0.0047 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) CPT PF07931.12 PXF41484.1 - 0.11 12.3 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TCR PF03638.15 PXF41486.1 - 0.00015 22.0 18.9 0.00024 21.3 18.9 1.3 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain Ribosomal_S27e PF01667.17 PXF41487.1 - 9.1e-28 95.7 5.3 1.1e-27 95.4 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 PXF41487.1 - 0.091 12.3 4.7 0.15 11.6 4.7 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding FAD_syn PF06574.12 PXF41488.1 - 6.5e-16 58.6 0.0 1.2e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 FAD synthetase CTP_transf_like PF01467.26 PXF41488.1 - 0.00012 22.3 0.0 0.00035 20.8 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like Brix PF04427.18 PXF41489.1 - 1.2e-31 110.3 0.2 1.5e-31 110.0 0.2 1.1 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 PXF41490.1 - 4.2e-58 196.8 0.0 5.7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41490.1 - 2.1e-33 115.7 0.0 2.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF41490.1 - 2.9e-07 30.1 0.0 6.6e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Mcp5_PH PF12814.7 PXF41490.1 - 0.033 14.3 1.1 0.77 9.9 1.1 2.3 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology CDC45 PF02724.14 PXF41490.1 - 0.65 8.2 16.2 0.89 7.8 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 PXF41490.1 - 0.75 9.2 20.8 1.3 8.4 20.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PXF41490.1 - 3.3 5.8 26.0 4.6 5.3 26.0 1.1 1 0 0 1 1 1 0 Nop14-like family Hydrolase_4 PF12146.8 PXF41491.1 - 2.8e-18 66.1 0.0 5.1e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF41491.1 - 1.5e-16 61.7 0.0 1.8e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF41491.1 - 1.5e-14 54.2 0.0 1.3e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 PXF41491.1 - 1.4e-05 24.9 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ndr PF03096.14 PXF41491.1 - 0.00026 19.8 0.1 0.0059 15.3 0.1 2.4 1 1 0 1 1 1 1 Ndr family UPF0227 PF05728.12 PXF41491.1 - 0.00099 19.1 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) DLH PF01738.18 PXF41491.1 - 0.0019 17.8 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 PXF41491.1 - 0.0088 15.7 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 PXF41491.1 - 0.017 15.0 0.0 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 PXF41491.1 - 0.03 14.2 0.0 0.63 9.9 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase DUF1057 PF06342.12 PXF41491.1 - 0.062 12.3 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 PXF41491.1 - 0.086 12.5 0.0 0.099 12.3 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 PXF41491.1 - 0.13 12.1 0.0 0.45 10.4 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 PXF41491.1 - 0.15 11.9 0.0 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase YecR PF13992.6 PXF41491.1 - 0.16 12.3 0.2 20 5.6 0.1 2.3 2 0 0 2 2 2 0 YecR-like lipoprotein DUF2048 PF09752.9 PXF41491.1 - 0.16 11.0 0.1 0.22 10.6 0.1 1.5 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 PXF41491.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FKBP_C PF00254.28 PXF41492.1 - 4.7e-29 100.6 0.0 9.2e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cdd1 PF11731.8 PXF41492.1 - 0.051 13.8 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus COG2 PF06148.11 PXF41492.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RETICULATA-like PF11891.8 PXF41493.1 - 3.2e-55 186.7 0.0 4.7e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Protein RETICULATA-related AAA PF00004.29 PXF41494.1 - 3.3e-23 82.5 0.0 4.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF41494.1 - 2.5e-10 41.0 5.2 0.001 19.5 0.1 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 PXF41494.1 - 1.7e-07 31.6 3.1 0.013 15.8 0.3 3.3 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 PXF41494.1 - 2.3e-07 31.1 1.5 0.014 15.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 PXF41494.1 - 2.4e-07 30.8 0.2 0.00078 19.2 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 PXF41494.1 - 7.9e-07 29.2 0.2 0.0037 17.2 0.1 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea TniB PF05621.11 PXF41494.1 - 2.1e-06 27.3 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 PXF41494.1 - 1e-05 25.5 0.1 0.32 10.9 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.6 PXF41494.1 - 1.1e-05 25.9 0.2 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 PXF41494.1 - 1.1e-05 25.2 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 PXF41494.1 - 1.3e-05 24.5 0.8 0.08 12.1 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain TsaE PF02367.17 PXF41494.1 - 4.7e-05 23.4 0.5 0.24 11.4 0.1 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 PXF41494.1 - 4.7e-05 23.0 0.3 0.031 13.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 PXF41494.1 - 5.4e-05 23.2 0.0 0.087 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 PXF41494.1 - 0.00021 20.6 4.1 0.0054 16.0 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_29 PF13555.6 PXF41494.1 - 0.00024 20.8 0.8 0.5 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 PXF41494.1 - 0.00026 21.5 0.2 0.54 10.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 PXF41494.1 - 0.00027 21.3 0.3 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PXF41494.1 - 0.00031 21.0 0.6 0.4 10.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 PXF41494.1 - 0.00048 20.7 0.1 0.33 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 PXF41494.1 - 0.002 16.9 0.0 0.53 8.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF41494.1 - 0.0026 17.5 3.5 0.28 10.9 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PXF41494.1 - 0.0071 16.2 0.0 0.61 9.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 PXF41494.1 - 0.0074 16.7 0.1 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 PXF41494.1 - 0.0077 16.4 0.1 1.9 8.7 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 PXF41494.1 - 0.0081 15.8 1.0 4 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 PXF41494.1 - 0.0098 15.7 0.2 3.3 7.4 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_lid_3 PF17862.1 PXF41494.1 - 0.012 15.4 0.1 0.035 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA+ lid domain DAP3 PF10236.9 PXF41494.1 - 0.013 14.7 0.2 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 PXF41494.1 - 0.014 15.3 0.2 3.9 7.4 0.0 2.7 2 0 0 2 2 2 0 NTPase dNK PF01712.19 PXF41494.1 - 0.014 15.2 0.0 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase T2SSE PF00437.20 PXF41494.1 - 0.015 14.4 0.1 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 PXF41494.1 - 0.016 14.6 0.3 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.12 PXF41494.1 - 0.021 14.6 0.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 PXF41494.1 - 0.028 14.1 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 PXF41494.1 - 0.04 13.2 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 PXF41494.1 - 0.052 13.6 1.6 17 5.4 0.1 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 PXF41494.1 - 0.064 12.7 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 PXF41494.1 - 0.067 13.2 0.1 7.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit G-alpha PF00503.20 PXF41494.1 - 0.076 12.2 0.0 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit PIF1 PF05970.14 PXF41494.1 - 0.088 12.0 0.2 8.1 5.5 0.0 2.9 3 0 0 3 3 3 0 PIF1-like helicase Mg_chelatase PF01078.21 PXF41494.1 - 0.1 12.0 0.7 7.9 5.8 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 PXF41494.1 - 0.11 12.4 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 PXF41494.1 - 0.12 11.6 0.0 6.3 5.9 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain RsgA_GTPase PF03193.16 PXF41494.1 - 0.14 12.1 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Adeno_IVa2 PF02456.15 PXF41494.1 - 0.17 10.6 0.1 0.48 9.2 0.1 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 PXF41494.1 - 0.2 11.1 0.1 15 5.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 PXF41494.1 - 0.21 10.9 1.6 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AFG1_ATPase PF03969.16 PXF41494.1 - 0.31 9.9 0.8 7.9 5.3 0.0 2.7 3 0 0 3 3 3 0 AFG1-like ATPase AAA_19 PF13245.6 PXF41494.1 - 2.3 8.6 8.6 3 8.2 0.5 3.2 3 1 0 3 3 3 0 AAA domain Transketolase_N PF00456.21 PXF41495.1 - 6.2e-154 511.9 0.0 9.7e-154 511.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PXF41495.1 - 8.1e-40 136.4 0.0 1.5e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PXF41495.1 - 3e-08 33.6 0.1 2.7e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Transketolase, C-terminal domain Peptidase_M17_N PF02789.17 PXF41495.1 - 0.032 14.1 0.1 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain SnoaL_2 PF12680.7 PXF41497.1 - 8.3e-06 26.4 0.0 1.3e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 PXF41497.1 - 2.9e-05 23.9 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 PXF41497.1 - 0.00052 20.4 0.0 0.00067 20.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4085 PF13315.6 PXF41497.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) SnoaL_2 PF12680.7 PXF41498.1 - 0.0012 19.5 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 PXF41498.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Troponin-I_N PF11636.8 PXF41498.1 - 0.33 10.9 1.8 0.58 10.2 1.8 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 Pkinase PF00069.25 PXF41502.1 - 1.4e-12 47.6 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41502.1 - 2.8e-06 26.8 0.0 3.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF41502.1 - 0.00034 20.0 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 PXF41502.1 - 0.00077 18.7 0.0 0.0017 17.6 0.0 1.5 2 0 0 2 2 2 1 Fructosamine kinase APH PF01636.23 PXF41502.1 - 0.0018 18.3 0.3 0.0069 16.3 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 PXF41504.1 - 7.1e-08 32.5 4.4 0.0024 18.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF41504.1 - 5.6e-07 29.9 3.3 0.021 15.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 PXF41504.1 - 0.00029 21.4 0.4 0.032 14.9 0.3 2.2 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-Di19 PF05605.12 PXF41504.1 - 0.00086 19.6 1.6 0.0021 18.3 1.6 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4729 PF15866.5 PXF41504.1 - 0.0025 17.2 1.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4729) Transpos_assoc PF13963.6 PXF41504.1 - 0.02 15.2 1.2 0.73 10.2 0.2 2.2 1 1 1 2 2 2 0 Transposase-associated domain zf-C2H2_8 PF15909.5 PXF41504.1 - 0.027 14.8 2.7 0.041 14.2 2.7 1.3 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 PXF41504.1 - 0.049 13.8 1.2 0.18 11.9 1.1 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 PXF41504.1 - 0.35 10.7 2.3 1.1 9.1 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EzrA PF06160.12 PXF41506.1 - 0.018 13.3 1.8 0.024 12.8 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF41506.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF41506.1 - 4.6 7.9 13.5 0.76 10.5 6.5 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Plant_tran PF04827.14 PXF41507.1 - 1.8e-52 177.9 0.0 2.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF41507.1 - 5e-13 49.0 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H2-Ydr279 PF09468.10 PXF41507.1 - 0.04 14.1 0.0 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain SQS_PSY PF00494.19 PXF41508.1 - 4.4e-45 154.2 0.0 8.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Podovirus_Gp16 PF05894.12 PXF41508.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) His_biosynth PF00977.21 PXF41509.1 - 4e-31 108.3 0.0 4.7e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ig_5 PF16681.5 PXF41509.1 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.3 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain LSM PF01423.22 PXF41510.1 - 8.5e-21 73.4 0.0 9.7e-21 73.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain LNS2 PF08235.13 PXF41510.1 - 0.065 12.7 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF150_C PF17384.2 PXF41510.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain zf-HIT PF04438.16 PXF41511.1 - 7.8e-07 28.9 12.3 1.5e-06 28.0 12.3 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 PXF41511.1 - 0.0084 16.2 8.9 0.024 14.7 8.9 1.7 1 0 0 1 1 1 1 MYND finger YL1_C PF08265.11 PXF41511.1 - 0.094 12.5 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Aldose_epim PF01263.20 PXF41512.1 - 3.1e-53 181.0 0.0 3.6e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AMPK1_CBM PF16561.5 PXF41513.1 - 1.8e-26 92.1 0.2 3.2e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ribonucleas_3_3 PF14622.6 PXF41514.1 - 8.4e-19 68.0 0.0 1.7e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PXF41514.1 - 7.4e-16 58.7 0.2 7.9e-15 55.4 0.1 2.6 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 PXF41514.1 - 0.0001 22.9 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif HTH_32 PF13565.6 PXF41514.1 - 0.035 14.7 1.8 0.31 11.7 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Plasmodium_Vir PF05795.11 PXF41515.1 - 3.8 6.8 4.2 4.9 6.5 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Polysacc_synt_2 PF02719.15 PXF41518.1 - 0.27 10.3 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_6 PF12697.7 PXF41519.1 - 1.7e-05 25.5 5.7 2.3e-05 25.1 5.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 PXF41519.1 - 0.0024 17.4 0.1 0.0075 15.8 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 PXF41519.1 - 0.024 14.4 0.1 0.15 11.7 0.0 2.1 2 1 1 3 3 3 0 PGAP1-like protein DUF915 PF06028.11 PXF41519.1 - 0.14 11.5 0.0 17 4.7 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PhoU PF01895.19 PXF41521.1 - 0.018 15.5 0.8 0.018 15.5 0.8 4.3 3 1 3 6 6 6 0 PhoU domain SlyX PF04102.12 PXF41521.1 - 0.03 14.9 3.3 0.03 14.9 3.3 5.0 3 2 2 5 5 5 0 SlyX RPW8 PF05659.11 PXF41521.1 - 0.052 13.2 4.2 2.6 7.7 0.2 2.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4094 PF13334.6 PXF41521.1 - 0.36 11.3 9.8 3.5 8.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Lge1 PF11488.8 PXF41521.1 - 0.86 9.8 4.8 2.9 8.2 1.0 3.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF812 PF05667.11 PXF41521.1 - 3.2 6.5 22.3 0.19 10.6 1.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF4446 PF14584.6 PXF41521.1 - 3.4 7.6 12.0 2.1 8.3 1.8 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) Syntaxin_2 PF14523.6 PXF41521.1 - 4.6 7.7 10.0 23 5.4 0.0 3.8 4 1 0 4 4 4 0 Syntaxin-like protein DUF4407 PF14362.6 PXF41521.1 - 5.6 6.2 18.1 0.74 9.1 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 PXF41521.1 - 8.1 6.6 18.7 0.07 13.3 0.9 3.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 PXF41521.1 - 8.5 6.4 23.2 10 6.2 2.2 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_31 PF01055.26 PXF41522.1 - 1.8e-42 146.1 0.0 3.5e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 EamA PF00892.20 PXF41523.1 - 1e-16 61.4 32.9 1.3e-08 35.1 14.8 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 PXF41523.1 - 2.3e-07 30.3 16.1 3.1e-07 29.9 9.5 2.9 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 PXF41523.1 - 0.00048 19.4 13.2 0.11 11.6 12.5 3.0 2 1 0 2 2 2 1 UAA transporter family Nuc_sug_transp PF04142.15 PXF41523.1 - 0.00057 19.1 4.0 0.15 11.2 0.1 2.5 3 0 0 3 3 3 2 Nucleotide-sugar transporter SLC35F PF06027.12 PXF41523.1 - 0.0011 18.5 12.8 0.0011 18.5 12.8 1.9 2 1 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 PXF41523.1 - 0.0019 17.2 9.1 0.028 13.3 0.2 2.4 2 1 1 3 3 3 2 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 PXF41523.1 - 0.066 13.3 10.6 0.46 10.5 5.1 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 CpeS PF09367.10 PXF41524.1 - 3.1e-48 163.9 0.5 3.7e-48 163.6 0.5 1.1 1 0 0 1 1 1 1 CpeS-like protein Myb_DNA-bind_4 PF13837.6 PXF41526.1 - 0.0028 18.0 0.1 0.0047 17.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF41526.1 - 0.0087 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PXF41526.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain NETI PF14044.6 PXF41526.1 - 0.18 11.6 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 NETI protein MFS_1 PF07690.16 PXF41527.1 - 1.4e-27 96.6 50.9 1.8e-15 56.8 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 PXF41528.1 - 2.5e-17 63.6 0.2 5.2e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S26 PF10502.9 PXF41529.1 - 1.1e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 PXF41529.1 - 1.6e-12 47.2 0.3 3.5e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 Peptidase S24-like SURF1 PF02104.15 PXF41530.1 - 1.5e-38 132.8 0.0 2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Ribosomal_S19e PF01090.19 PXF41530.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e Mating_C PF12737.7 PXF41530.1 - 0.12 11.6 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RETICULATA-like PF11891.8 PXF41532.1 - 2.6e-47 160.9 0.0 3.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related PRP3 PF08572.10 PXF41533.1 - 1.6e-59 201.4 9.5 1.6e-59 201.4 9.5 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 PXF41533.1 - 9.6e-37 126.3 0.1 9.6e-37 126.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF2828 PF11443.8 PXF41533.1 - 0.19 9.7 2.2 0.39 8.8 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) F-box PF00646.33 PXF41534.1 - 2.8e-08 33.4 0.1 5.9e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF41534.1 - 2.6e-05 24.0 0.5 7e-05 22.6 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PXF41534.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box PIP5K PF01504.18 PXF41535.1 - 1.4e-66 224.6 1.7 3e-66 223.5 1.7 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_35 PF01301.19 PXF41536.1 - 7e-60 203.3 1.1 2.5e-44 152.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 PXF41536.1 - 1.6e-10 41.5 0.0 8.2e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 PXF41536.1 - 0.0017 17.7 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 PXF41536.1 - 0.0068 15.9 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) COX6A PF02046.15 PXF41537.1 - 0.00013 22.4 0.0 0.00055 20.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF1995 PF09353.10 PXF41539.1 - 4.3e-25 88.9 0.1 5.4e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) zf-RING_2 PF13639.6 PXF41540.1 - 2e-10 40.8 12.2 4.6e-10 39.7 12.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF41540.1 - 5.3e-09 35.7 7.4 5.3e-09 35.7 7.4 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF41540.1 - 1.7e-05 24.6 12.2 3.6e-05 23.5 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF41540.1 - 5.2e-05 23.4 8.2 0.00012 22.2 8.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PXF41540.1 - 0.00085 19.1 8.9 0.00085 19.1 8.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF41540.1 - 0.00095 19.0 10.8 0.0021 17.9 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF41540.1 - 0.001 19.0 10.7 0.0027 17.6 10.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF41540.1 - 0.0038 17.2 6.2 0.011 15.7 6.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF41540.1 - 0.02 14.7 10.9 0.051 13.4 10.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Sensor PF13796.6 PXF41540.1 - 0.025 14.6 0.5 0.025 14.6 0.5 2.4 2 1 1 3 3 3 0 Putative sensor YwiC PF14256.6 PXF41540.1 - 0.34 11.2 7.8 1.4 9.3 2.3 2.2 2 0 0 2 2 2 0 YwiC-like protein zf-ANAPC11 PF12861.7 PXF41540.1 - 0.45 10.6 7.9 1.2 9.2 7.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Acyltransferase PF01553.21 PXF41541.1 - 2.4e-12 46.6 0.0 4.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Mito_carr PF00153.27 PXF41542.1 - 3e-61 203.4 2.4 4.3e-21 74.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane_2 PF06472.15 PXF41543.1 - 9e-54 182.7 6.9 1.2e-53 182.3 6.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF41543.1 - 4.3e-15 56.4 0.0 1.7e-14 54.5 0.0 2.1 2 1 0 2 2 2 1 ABC transporter SbmA_BacA PF05992.12 PXF41543.1 - 3.1e-12 46.6 5.1 1.7e-11 44.1 5.1 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 PXF41543.1 - 3.9e-05 23.4 6.7 8.2e-05 22.4 6.7 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 PXF41543.1 - 0.0042 16.8 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PXF41543.1 - 0.0084 16.5 0.0 0.056 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF41543.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 PXF41543.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 PXF41543.1 - 0.084 13.1 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PXF41543.1 - 0.088 12.4 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Amnionless PF14828.6 PXF41543.1 - 0.093 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4164 PF13747.6 PXF41543.1 - 0.19 12.0 1.1 1.4 9.2 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Chorismate_bind PF00425.18 PXF41544.1 - 6.3e-87 291.4 0.0 1.1e-86 290.6 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 PXF41544.1 - 2.5e-38 131.8 0.0 4.1e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 PXF41544.1 - 1.9e-21 76.8 0.3 5.7e-19 68.7 0.0 2.6 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 PXF41544.1 - 3.4e-05 23.7 0.0 6.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DUF5095 PF17016.5 PXF41545.1 - 0.2 11.3 0.0 1.3 8.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5095) IF4E PF01652.18 PXF41546.1 - 1.7e-45 154.6 0.2 2.1e-45 154.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Myb_DNA-bind_7 PF15963.5 PXF41547.1 - 9.1e-25 86.4 0.1 9.1e-25 86.4 0.1 2.0 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 PXF41547.1 - 0.00016 21.8 0.2 0.00027 21.0 0.2 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 PXF41547.1 - 0.00071 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2076 PF09849.9 PXF41547.1 - 0.11 12.6 26.1 0.13 12.2 11.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Spt20 PF12090.8 PXF41547.1 - 0.13 11.8 41.0 0.23 11.1 7.1 2.3 2 0 0 2 2 2 0 Spt20 family SpoIIP PF07454.11 PXF41547.1 - 0.27 10.7 9.9 0.16 11.4 4.7 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF3306 PF11748.8 PXF41547.1 - 1.1 10.2 18.8 0.51 11.2 6.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SURF6 PF04935.12 PXF41547.1 - 1.1 9.0 17.3 0.62 9.8 10.1 2.4 2 0 0 2 2 2 0 Surfeit locus protein 6 DUF3391 PF11871.8 PXF41547.1 - 2 8.9 15.6 0.53 10.8 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Plasmodium_Vir PF05795.11 PXF41547.1 - 2.2 7.6 15.4 0.39 10.1 0.4 2.1 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF2722 PF10846.8 PXF41547.1 - 2.4 7.0 33.0 0.63 8.9 15.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MMR1 PF08505.10 PXF41547.1 - 3.3 7.9 20.9 1.5 9.1 11.8 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Prothymosin PF03247.14 PXF41547.1 - 4.4 7.8 9.8 7.2 7.1 0.7 2.7 3 0 0 3 3 2 0 Prothymosin/parathymosin family PIEZO PF15917.5 PXF41547.1 - 6.6 6.1 13.4 0.89 9.0 6.9 2.2 2 0 0 2 2 2 0 Piezo Androgen_recep PF02166.16 PXF41547.1 - 7.8 5.2 35.4 0.68 8.7 15.8 2.2 2 0 0 2 2 2 0 Androgen receptor Ribosomal_L32e PF01655.18 PXF41548.1 - 7.6e-49 164.6 1.0 1e-48 164.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 TPR_19 PF14559.6 PXF41549.1 - 0.0012 19.3 11.1 0.057 13.9 0.0 4.6 2 2 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 PXF41549.1 - 0.0097 15.4 0.4 0.085 12.3 0.2 2.4 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_2 PF07719.17 PXF41549.1 - 0.0099 15.9 1.7 2.9 8.2 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF41549.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.9 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 PXF41549.1 - 0.41 11.4 0.1 0.41 11.4 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF41549.1 - 5.3 7.8 14.5 2.1 9.0 1.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DoxX_2 PF13564.6 PXF41550.1 - 6e-08 32.7 9.1 1e-07 32.0 9.1 1.4 1 1 0 1 1 1 1 DoxX-like family PolC_DP2 PF03833.13 PXF41550.1 - 0.048 11.5 0.1 0.06 11.2 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FUSC_2 PF13515.6 PXF41551.1 - 6.9e-06 26.2 6.4 6.9e-06 26.2 6.4 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 PXF41551.1 - 0.0014 17.6 7.4 0.005 15.7 7.4 1.9 1 1 0 1 1 1 1 Aluminium activated malate transporter 3HCDH_RFF PF18321.1 PXF41551.1 - 0.016 15.6 0.3 0.061 13.8 0.3 2.0 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Arm PF00514.23 PXF41553.1 - 3.7e-84 274.5 16.6 2.7e-12 46.3 0.0 8.5 8 1 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PXF41553.1 - 4.9e-23 81.2 0.9 5.2e-06 26.8 0.0 6.7 4 3 3 7 7 7 3 HEAT-like repeat IBB PF01749.20 PXF41553.1 - 6.5e-22 77.8 0.6 1.6e-21 76.5 0.6 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 PXF41553.1 - 1.6e-19 70.1 0.0 2e-05 24.9 0.0 5.5 2 1 2 5 5 5 4 HEAT repeats Arm_3 PF16186.5 PXF41553.1 - 2.8e-18 65.2 0.6 1.9e-17 62.5 1.6 2.0 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 PXF41553.1 - 8.5e-17 59.8 0.5 0.00041 20.4 0.0 7.7 8 0 0 8 8 7 2 HEAT repeat Arm_2 PF04826.13 PXF41553.1 - 9.8e-08 31.8 0.0 0.0078 15.7 0.0 3.3 2 1 1 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 PXF41553.1 - 6.2e-06 26.3 0.0 1.3 9.2 0.0 4.3 4 0 0 4 4 4 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 PXF41553.1 - 0.00011 22.2 0.0 0.52 10.4 0.0 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 PXF41553.1 - 0.0011 18.3 0.1 0.055 12.8 0.1 2.7 2 1 1 3 3 3 1 V-ATPase subunit H RICTOR_V PF14668.6 PXF41553.1 - 0.0013 18.9 4.1 4.5 7.6 0.0 5.0 4 2 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 CTNNBL PF08216.11 PXF41553.1 - 0.0046 17.1 0.4 3.6 7.8 0.0 4.1 5 0 0 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_PBS PF03130.16 PXF41553.1 - 0.0059 17.2 3.4 0.89 10.4 0.5 5.1 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 PXF41553.1 - 0.019 14.3 0.0 4.5 6.5 0.0 2.5 1 1 1 2 2 2 0 Mo25-like DUF3361 PF11841.8 PXF41553.1 - 0.032 14.2 0.1 3 7.8 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DUF1764 PF08576.10 PXF41554.1 - 0.23 12.4 5.1 0.32 11.9 5.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4834 PF16118.5 PXF41554.1 - 0.39 11.7 4.1 0.59 11.1 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EF-hand_7 PF13499.6 PXF41556.1 - 1.5e-17 63.8 4.1 1.7e-12 47.6 1.9 2.5 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PXF41556.1 - 3.4e-15 54.4 5.2 2e-05 23.8 1.5 3.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 PXF41556.1 - 6.8e-14 50.6 5.5 1.5e-05 24.2 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PXF41556.1 - 9.2e-14 50.1 4.5 8.1e-06 25.4 1.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PXF41556.1 - 1.6e-05 24.7 3.0 7.2e-05 22.6 1.9 2.4 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PXF41556.1 - 0.00029 21.1 0.4 0.081 13.2 0.0 2.5 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PXF41556.1 - 0.00099 19.3 3.0 0.0067 16.6 2.9 2.4 1 1 0 1 1 1 1 Dockerin type I domain Sigma54_CBD PF04963.13 PXF41556.1 - 0.003 17.5 0.1 0.66 9.8 0.0 2.1 2 0 0 2 2 2 2 Sigma-54 factor, core binding domain RST PF12174.8 PXF41556.1 - 0.046 13.7 0.5 0.75 9.8 0.0 2.7 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Glyco_tranf_2_2 PF10111.9 PXF41556.1 - 0.047 13.2 0.3 0.084 12.3 0.2 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 DIMCO_N PF16844.5 PXF41556.1 - 0.091 13.1 0.6 9.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal TRAF_BIRC3_bd PF16673.5 PXF41556.1 - 0.11 12.3 1.6 0.24 11.2 1.6 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain V-ATPase_C PF03223.15 PXF41556.1 - 0.13 11.7 0.5 0.19 11.1 0.5 1.2 1 0 0 1 1 1 0 V-ATPase subunit C DnaJ_C PF01556.18 PXF41557.1 - 1.1e-26 93.7 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain PHD PF00628.29 PXF41560.1 - 0.00013 21.8 2.3 0.00026 20.8 2.3 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 PXF41560.1 - 0.012 15.4 1.3 0.033 14.1 1.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mito_carr PF00153.27 PXF41561.1 - 6.2e-68 224.8 3.1 2.4e-22 78.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF41561.1 - 0.0005 19.3 0.8 2.5 7.2 0.1 3.4 2 1 0 3 3 3 3 Gammaproteobacterial serine protease EutK_C PF16365.5 PXF41561.1 - 0.0075 16.3 0.0 0.19 11.8 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilization protein EutK C-terminus FmiP_Thoc5 PF09766.9 PXF41562.1 - 1.5e-36 126.5 2.6 5.6e-21 75.2 4.7 2.2 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 RWD PF05773.22 PXF41562.1 - 0.14 12.4 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 RWD domain DUF2730 PF10805.8 PXF41562.1 - 0.18 11.9 2.1 2 8.5 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.22 PXF41562.1 - 0.37 11.0 5.3 0.66 10.2 1.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.18 PXF41562.1 - 2.3 9.0 4.7 0.82 10.4 0.4 2.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 PXF41562.1 - 8.9 6.3 9.4 0.58 10.2 2.7 2.4 3 1 0 3 3 3 0 Laminin Domain II Pyr_redox_2 PF07992.14 PXF41563.1 - 8e-72 241.9 3.4 1.3e-71 241.3 3.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PXF41563.1 - 1.5e-38 131.4 2.0 2.9e-38 130.5 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PXF41563.1 - 5.2e-23 81.4 8.0 4.3e-19 68.8 0.4 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF41563.1 - 1.8e-14 53.7 4.3 8.6e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PXF41563.1 - 3.4e-11 43.2 2.7 3.3e-10 39.9 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 PXF41563.1 - 5.2e-11 42.3 1.2 3.7e-09 36.1 0.8 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PXF41563.1 - 8.1e-09 35.1 1.2 0.00071 18.9 0.1 3.5 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 PXF41563.1 - 9.1e-09 34.9 10.1 1e-06 28.1 2.6 4.1 2 1 2 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 PXF41563.1 - 1.6e-07 31.4 3.9 1.3e-05 25.3 0.7 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 PXF41563.1 - 2.5e-06 26.9 1.4 0.022 13.9 0.1 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 PXF41563.1 - 8.5e-06 24.7 12.1 0.00023 20.0 1.3 3.8 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.24 PXF41563.1 - 5.7e-05 22.9 13.2 0.022 14.3 0.6 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF41563.1 - 6.6e-05 22.1 0.1 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 PXF41563.1 - 0.00062 19.1 0.9 0.0041 16.4 0.0 2.5 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 PXF41563.1 - 0.011 15.0 8.9 0.065 12.5 1.1 3.0 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 PXF41563.1 - 0.013 15.4 3.3 0.039 13.9 0.1 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 PXF41563.1 - 0.074 13.6 0.0 10 6.7 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain NFACT-R_1 PF05670.13 PXF41564.1 - 1.2e-43 148.2 0.9 2.2e-43 147.4 0.9 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Nucleoporin2 PF04096.14 PXF41564.1 - 0.00077 19.6 2.7 0.0013 18.9 2.7 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase FAM199X PF15814.5 PXF41564.1 - 1.8 7.5 5.7 2.5 7.1 5.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X tRNA-synt_2d PF01409.20 PXF41565.1 - 3.8e-53 180.5 0.0 5.9e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 PXF41565.1 - 2.7e-21 75.8 0.0 9.3e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Peptidase_S8 PF00082.22 PXF41566.1 - 4e-27 95.3 3.0 4e-27 95.3 3.0 1.8 2 0 0 2 2 2 1 Subtilase family DUF3147 PF11345.8 PXF41566.1 - 0.018 15.4 0.2 0.047 14.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Peptidase_M48 PF01435.18 PXF41567.1 - 1.8e-24 86.6 0.0 3.8e-24 85.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 TPR_14 PF13428.6 PXF41568.1 - 1.8e-43 143.5 57.1 3.3e-06 27.5 0.1 20.8 12 8 11 23 23 22 11 Tetratricopeptide repeat TPR_2 PF07719.17 PXF41568.1 - 1.8e-39 130.7 19.4 1e-05 25.2 0.0 18.8 20 0 0 20 20 18 7 Tetratricopeptide repeat TPR_19 PF14559.6 PXF41568.1 - 2.2e-28 98.5 17.7 1.1e-05 25.8 0.2 12.6 12 3 1 13 13 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 PXF41568.1 - 1.9e-26 92.4 42.5 1.1e-05 25.9 0.3 13.1 11 4 0 12 12 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 PXF41568.1 - 2.5e-25 87.0 10.8 0.0032 17.7 0.0 13.6 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 PXF41568.1 - 4.8e-21 73.1 2.7 0.01 16.0 0.1 14.0 15 0 0 15 15 15 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF41568.1 - 1.9e-19 69.7 30.9 0.015 15.5 0.0 12.1 9 4 3 12 12 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 PXF41568.1 - 6.5e-18 63.7 6.0 0.0004 20.1 0.1 12.6 16 0 0 16 16 15 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF41568.1 - 1.8e-15 56.3 10.5 0.0036 16.9 0.2 10.8 12 1 1 13 13 13 2 TPR repeat TPR_6 PF13174.6 PXF41568.1 - 6e-11 42.3 16.4 3.9 8.3 0.0 14.5 20 0 0 20 20 16 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF41568.1 - 5.8e-10 38.9 30.2 0.00026 20.3 6.5 7.3 4 3 1 6 6 6 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF41568.1 - 1e-07 32.0 8.1 0.36 10.8 0.0 8.5 8 4 3 11 11 11 2 Mad3/BUB1 homology region 1 Suf PF05843.14 PXF41568.1 - 2.8e-07 30.8 0.2 0.0091 16.0 0.0 4.4 5 0 0 5 5 4 2 Suppressor of forked protein (Suf) TPR_9 PF13371.6 PXF41568.1 - 9.3e-07 28.9 21.0 0.13 12.4 0.1 8.6 7 3 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF41568.1 - 7.4e-05 22.5 7.8 2.8 8.2 0.0 8.0 8 0 0 8 8 6 1 Tetratricopeptide repeat FAT PF02259.23 PXF41568.1 - 0.0047 16.2 16.8 0.072 12.3 0.1 6.1 5 4 1 6 6 6 2 FAT domain ANAPC3 PF12895.7 PXF41568.1 - 0.013 15.7 5.1 3.3 8.0 0.0 5.5 6 0 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PXF41568.1 - 0.088 12.9 1.0 4.3 7.5 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 PXF41568.1 - 0.12 11.1 0.8 9.4 4.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) Wzy_C_2 PF11846.8 PXF41568.1 - 0.13 12.2 2.1 0.45 10.4 0.1 3.1 4 0 0 4 4 2 0 Virulence factor membrane-bound polymerase, C-terminal TAP_C PF03943.13 PXF41568.1 - 3 7.6 5.3 3.1 7.5 0.1 3.4 4 0 0 4 4 4 0 TAP C-terminal domain Hydrolase_3 PF08282.12 PXF41569.1 - 3.9e-09 36.6 0.0 5.6e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF41569.1 - 0.0016 18.0 0.0 0.21 11.1 0.0 2.9 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase UPF0029 PF01205.19 PXF41570.1 - 1.6e-28 99.1 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Herpes_glycoH_C PF17488.2 PXF41570.1 - 0.039 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain Mito_carr PF00153.27 PXF41571.1 - 9.5e-64 211.4 3.8 2.6e-21 75.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M14 PF00246.24 PXF41572.1 - 6e-25 88.6 0.0 9.8e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase GGDEF_2 PF17853.1 PXF41572.1 - 0.022 15.0 0.4 0.067 13.5 0.1 2.0 2 0 0 2 2 2 0 GGDEF-like domain MFS_1 PF07690.16 PXF41573.1 - 7.7e-28 97.4 46.3 7.7e-28 97.4 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PXF41573.1 - 3.7e-09 36.0 6.3 3.7e-09 36.0 6.3 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 PXF41573.1 - 0.019 13.9 30.6 0.18 10.6 8.8 2.3 1 1 1 2 2 2 0 MFS_1 like family WSK PF03832.13 PXF41573.1 - 0.28 10.9 0.3 0.51 10.1 0.3 1.4 1 0 0 1 1 1 0 WSK motif PsbU PF06514.11 PXF41574.1 - 1.4e-27 95.5 0.1 1.9e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 PXF41574.1 - 2.7e-05 24.3 0.0 0.00019 21.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif MSP PF01716.18 PXF41575.1 - 3.1e-97 324.5 0.5 3.7e-97 324.2 0.5 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide p450 PF00067.22 PXF41576.1 - 8.2e-19 67.7 0.0 3.3e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Hydrolase_4 PF12146.8 PXF41577.1 - 8.7e-12 44.8 0.0 1.3e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF41577.1 - 2.9e-09 37.9 0.1 5.2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF41577.1 - 1.7e-05 24.6 0.1 0.00066 19.4 0.2 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PXF41577.1 - 2.1e-05 24.1 0.0 0.00018 21.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PXF41577.1 - 2.8e-05 24.0 0.0 0.00032 20.6 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 PXF41577.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 PXF41577.1 - 0.0081 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 PXF41577.1 - 0.044 13.3 0.0 1.4 8.4 0.0 2.4 1 1 1 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 PXF41577.1 - 0.2 11.0 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Big_7 PF17957.1 PXF41578.1 - 0.14 12.9 0.2 0.41 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig domain zf-C2H2 PF00096.26 PXF41579.1 - 3.6e-15 55.5 42.4 8.9e-05 22.7 1.2 5.9 5 1 1 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF41579.1 - 3.5e-14 52.3 44.2 0.0013 19.4 3.6 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF41579.1 - 1.3e-09 38.0 32.7 0.0045 17.4 0.4 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PXF41579.1 - 1.5e-09 37.8 31.9 0.00077 19.7 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PXF41579.1 - 9.7e-09 35.0 33.2 0.0017 18.3 2.8 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PXF41579.1 - 1e-07 31.6 27.6 0.024 14.6 0.0 6.0 6 1 0 6 6 6 4 zinc-finger of a C2HC-type zf-met PF12874.7 PXF41579.1 - 1.7e-07 31.4 27.2 0.0095 16.3 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PXF41579.1 - 7.2e-05 23.0 1.5 7.2e-05 23.0 1.5 3.5 3 1 0 3 3 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PXF41579.1 - 0.00087 19.0 25.2 0.013 15.2 0.5 4.8 5 0 0 5 5 5 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 PXF41579.1 - 0.0036 17.4 23.2 0.28 11.3 0.7 4.5 3 1 1 4 4 4 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 PXF41579.1 - 0.0062 17.2 5.0 0.0062 17.2 5.0 2.4 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats Rubredoxin PF00301.20 PXF41579.1 - 0.016 15.2 0.3 0.016 15.2 0.3 3.8 4 0 0 4 4 4 0 Rubredoxin ADK_lid PF05191.14 PXF41579.1 - 0.017 15.1 16.3 1.3 9.1 0.1 4.1 3 2 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_12 PF18658.1 PXF41579.1 - 0.04 13.5 0.4 0.24 11.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 PXF41579.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.1 3 1 1 4 4 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2256 PF10013.9 PXF41579.1 - 0.22 11.7 15.8 7.8 6.7 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_Hakai PF18408.1 PXF41579.1 - 0.29 10.9 17.5 0.43 10.3 0.1 4.5 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf-BED PF02892.15 PXF41579.1 - 0.32 11.0 19.1 0.26 11.3 1.2 4.3 3 1 1 4 4 4 0 BED zinc finger zf_UBZ PF18439.1 PXF41579.1 - 0.52 9.9 21.6 10 5.8 0.5 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 PXF41579.1 - 0.93 9.8 19.1 0.066 13.5 5.6 3.5 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain zinc-ribbons_6 PF07191.12 PXF41579.1 - 1.1 9.3 23.1 0.68 9.9 2.2 3.5 3 2 0 3 3 3 0 zinc-ribbons Rad50_zn_hook PF04423.14 PXF41579.1 - 1.2 9.0 13.2 2 8.3 0.2 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif HypA PF01155.19 PXF41579.1 - 1.7 8.7 17.6 0.32 11.0 0.2 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 PXF41579.1 - 2.6 8.4 13.0 1.4 9.3 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon Sgf11 PF08209.11 PXF41579.1 - 4.3 7.0 20.0 14 5.3 0.2 5.1 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) ArgoMid PF16487.5 PXF41588.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute Translin PF01997.16 PXF41592.1 - 5e-47 160.6 0.2 5.9e-47 160.3 0.2 1.1 1 0 0 1 1 1 1 Translin family YlbD_coat PF14071.6 PXF41592.1 - 0.0042 17.3 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 1 Putative coat protein IDO PF01231.18 PXF41592.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase NPV_P10 PF05531.12 PXF41592.1 - 0.063 13.7 0.7 0.71 10.4 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.11 PXF41592.1 - 0.15 12.1 2.4 9.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2277 PF10041.9 PXF41593.1 - 0.093 13.1 0.2 0.22 11.9 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) V-SNARE_C PF12352.8 PXF41594.1 - 7.1e-06 26.2 7.4 1.2e-05 25.4 0.2 3.4 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PXF41594.1 - 0.0016 18.3 2.0 0.015 15.2 0.2 2.7 2 0 0 2 2 2 1 Sec20 LOH1CR12 PF10158.9 PXF41594.1 - 0.0043 17.1 1.1 0.035 14.1 0.2 2.3 2 0 0 2 2 2 1 Tumour suppressor protein Flagellin_N PF00669.20 PXF41594.1 - 0.036 14.2 10.1 1.3 9.2 2.0 2.9 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF948 PF06103.11 PXF41594.1 - 0.097 12.9 3.8 0.48 10.7 0.7 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1843 PF08898.10 PXF41594.1 - 0.24 11.9 2.6 0.37 11.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF5089 PF17002.5 PXF41594.1 - 0.41 10.5 22.6 0.5 10.2 6.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF5089) Nrap_D4 PF17405.2 PXF41595.1 - 2.2e-28 99.1 0.0 4.9e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 PXF41595.1 - 1.3e-26 93.5 0.0 2.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 PXF41595.1 - 1.3e-21 77.0 0.0 2.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 PXF41595.1 - 4.6e-14 52.8 0.1 1.1e-13 51.6 0.1 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 PXF41595.1 - 7e-12 45.7 0.0 1.8e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 EAP30 PF04157.16 PXF41595.1 - 0.11 11.8 0.2 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 EAP30/Vps36 family DUF2064 PF09837.9 PXF41596.1 - 1.2e-29 102.6 0.0 1.9e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) CofC PF01983.16 PXF41596.1 - 6.4e-07 28.8 0.0 7.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Guanylyl transferase CofC like LolB PF03550.14 PXF41596.1 - 0.035 14.2 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Raptor_N PF14538.6 PXF41596.1 - 0.047 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain APH PF01636.23 PXF41596.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 PXF41597.1 - 2.8e-25 88.9 2.3 3e-24 85.6 2.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF41597.1 - 6e-11 42.3 2.5 5.8e-10 39.1 2.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PXF41597.1 - 1.4e-06 28.0 0.1 1.9e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 PXF41597.1 - 3.7e-06 27.0 0.4 7e-06 26.1 0.4 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PXF41597.1 - 0.024 14.9 0.2 0.067 13.4 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain tRNA-synt_2 PF00152.20 PXF41599.1 - 8.4e-86 287.9 0.0 1.5e-85 287.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PXF41599.1 - 6.5e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF41599.1 - 0.042 13.3 0.2 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Porin_3 PF01459.22 PXF41600.1 - 8.6e-50 169.7 0.0 1e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin RBFA PF02033.18 PXF41601.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Ribosome-binding factor A YpjP PF14005.6 PXF41601.1 - 0.085 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 YpjP-like protein ING PF12998.7 PXF41601.1 - 0.41 11.3 4.6 0.2 12.3 1.2 2.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ubie_methyltran PF01209.18 PXF41602.1 - 7.9e-65 218.4 0.0 9.9e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PXF41602.1 - 5.8e-17 62.2 0.0 7.4e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41602.1 - 2.2e-15 57.0 0.0 4.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41602.1 - 5.2e-12 45.8 0.0 6.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41602.1 - 3.2e-09 36.8 0.0 4.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41602.1 - 1.5e-07 32.1 0.0 2.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF41602.1 - 0.0086 15.6 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_5 PF01795.19 PXF41602.1 - 0.011 15.3 0.0 2.4 7.6 0.0 2.2 1 1 0 2 2 2 0 MraW methylase family zf-C2H2_4 PF13894.6 PXF41604.1 - 4.9e-11 42.5 37.2 0.0037 18.0 3.4 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF41604.1 - 5.9e-11 42.2 37.9 0.00012 22.3 2.0 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF41604.1 - 2.1e-08 34.2 37.1 0.031 14.7 0.4 5.5 5 0 0 5 5 5 5 Zinc-finger double domain HNH_5 PF14279.6 PXF41604.1 - 7.2e-05 22.6 9.2 5.5 6.9 0.3 5.5 5 1 0 5 5 5 2 HNH endonuclease zf-C2H2_3rep PF18868.1 PXF41604.1 - 0.00016 22.3 17.1 0.37 11.5 0.4 4.5 2 1 3 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PXF41604.1 - 0.00041 20.5 30.6 0.011 16.0 3.7 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF41604.1 - 0.0042 17.4 25.0 2.4 8.5 0.0 4.5 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PXF41604.1 - 0.0095 16.0 4.4 0.0095 16.0 4.4 3.8 3 1 1 4 4 4 1 Zinc ribbon domain zf-met PF12874.7 PXF41604.1 - 0.019 15.4 23.4 0.73 10.3 1.0 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.14 PXF41604.1 - 0.11 12.7 6.6 0.27 11.5 2.9 2.7 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_9 PF14369.6 PXF41604.1 - 0.26 11.6 9.9 18 5.7 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon zinc_ribbon_15 PF17032.5 PXF41604.1 - 0.29 11.9 16.1 2.2 9.1 2.6 3.1 1 1 1 3 3 3 0 zinc-ribbon family zf-DNA_Pol PF08996.10 PXF41604.1 - 0.64 9.7 13.2 0.21 11.3 2.7 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Endonuclease_7 PF02945.15 PXF41604.1 - 1.4 8.9 16.5 10 6.1 0.2 3.4 1 1 1 2 2 2 0 Recombination endonuclease VII DUF629 PF04780.12 PXF41604.1 - 3.7 6.0 27.9 0.23 9.9 6.4 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF629) RVT_2 PF07727.14 PXF41606.1 - 3.3e-13 49.9 0.0 5.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LBR_tudor PF09465.10 PXF41606.1 - 0.0054 16.5 0.2 0.12 12.2 0.1 2.6 3 0 0 3 3 3 1 Lamin-B receptor of TUDOR domain rve PF00665.26 PXF41606.1 - 0.051 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DAN PF03045.15 PXF41607.1 - 0.0051 16.8 2.4 0.051 13.6 0.3 2.1 1 1 1 2 2 2 2 DAN domain DUF4218 PF13960.6 PXF41609.1 - 0.19 11.3 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Abhydrolase_6 PF12697.7 PXF41610.1 - 7.8e-14 52.8 0.0 1.4e-13 52.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MR_MLE_C PF13378.6 PXF41610.1 - 1.9e-13 50.5 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like Abhydrolase_1 PF00561.20 PXF41610.1 - 8.7e-11 41.9 0.1 9.8e-08 31.9 0.1 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF41610.1 - 3.8e-07 29.6 0.0 7.8e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 PXF41610.1 - 4.2e-07 29.7 0.0 1.8e-05 24.4 0.0 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 PXF41610.1 - 3.5e-06 27.3 0.0 1.9e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.7 PXF41610.1 - 0.00028 19.9 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 PXF41610.1 - 0.0011 18.9 0.0 0.0028 17.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 PXF41610.1 - 0.0086 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase FSH1 PF03959.13 PXF41610.1 - 0.037 13.7 0.0 0.2 11.3 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 PXF41610.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Enolase_C PF00113.22 PXF41610.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Lipase_3 PF01764.25 PXF41610.1 - 0.19 11.6 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF547 PF04784.14 PXF41611.1 - 3.5e-33 114.3 0.0 7.4e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 PXF41611.1 - 9.1e-24 83.3 0.0 2.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF3_N PF09440.10 PXF41612.1 - 5.5e-41 140.1 0.7 1.1e-40 139.2 0.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 PXF41612.1 - 1.9e-18 66.9 0.1 6.7e-18 65.1 0.1 2.0 1 0 0 1 1 1 1 PCI domain DnaB PF00772.21 PXF41612.1 - 0.023 14.7 0.1 0.075 13.1 0.1 1.8 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain RNase_PH PF01138.21 PXF41613.1 - 3.2e-21 76.2 0.0 6.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF41613.1 - 9.3e-07 28.8 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATP-grasp_6 PF18419.1 PXF41613.1 - 0.093 12.4 0.1 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 ATP-grasp-like domain Sec10 PF07393.11 PXF41614.1 - 0.17 10.3 6.7 0.23 9.8 6.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Dicty_REP PF05086.12 PXF41614.1 - 4.3 5.2 7.2 5.9 4.7 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1279 PF06916.13 PXF41615.1 - 6e-17 62.0 0.0 9.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) GrpE PF01025.19 PXF41616.1 - 9.3e-42 142.5 3.3 1.3e-41 142.1 3.3 1.1 1 0 0 1 1 1 1 GrpE APG17 PF04108.12 PXF41616.1 - 0.0034 16.6 2.8 0.0045 16.2 2.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 HrpB7 PF09486.10 PXF41616.1 - 0.01 16.2 1.6 0.018 15.5 0.3 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 PXF41616.1 - 0.036 13.2 1.6 0.047 12.8 1.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLYB PF05289.11 PXF41616.1 - 0.048 13.9 0.3 0.088 13.0 0.2 1.5 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein Pex19 PF04614.12 PXF41616.1 - 0.11 12.3 3.2 0.15 11.8 3.2 1.2 1 0 0 1 1 1 0 Pex19 protein family DUF1664 PF07889.12 PXF41616.1 - 0.14 12.2 4.0 2.7 8.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2408 PF10303.9 PXF41616.1 - 0.14 12.7 2.0 0.28 11.8 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ADIP PF11559.8 PXF41616.1 - 0.2 11.7 5.3 0.075 13.1 1.9 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 PXF41616.1 - 0.27 11.5 8.9 0.21 11.9 5.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FliS PF02561.14 PXF41616.1 - 0.45 10.8 2.2 1.6 9.0 0.1 2.2 1 1 1 2 2 2 0 Flagellar protein FliS Ccdc124 PF06244.12 PXF41616.1 - 0.79 10.3 6.1 1.4 9.5 6.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Apc13p PF05839.11 PXF41617.1 - 1.2e-06 28.6 4.4 1.2e-05 25.4 4.4 2.0 1 1 0 1 1 1 1 Apc13p protein Cnd1 PF12717.7 PXF41618.1 - 1.7e-47 161.5 4.4 6.9e-45 153.0 0.1 5.3 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PXF41618.1 - 2.7e-07 29.5 13.2 3.3e-06 26.0 0.9 4.4 4 1 0 4 4 4 2 Adaptin N terminal region HEAT_2 PF13646.6 PXF41618.1 - 1.2e-05 25.6 7.3 0.0037 17.6 0.0 4.9 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.22 PXF41618.1 - 4.1e-05 23.5 11.6 0.17 12.2 0.1 5.6 6 0 0 6 6 6 3 HEAT repeat Cnd3 PF12719.7 PXF41618.1 - 7.7e-05 22.0 8.8 0.00037 19.8 2.7 3.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 PXF41618.1 - 0.062 13.5 2.3 14 5.9 0.1 4.9 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 PXF41618.1 - 0.16 12.5 7.8 0.21 12.1 0.0 4.6 5 1 1 6 6 6 0 HEAT-like repeat Cnd1_N PF12922.7 PXF41618.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term NAD_binding_1 PF00175.21 PXF41619.1 - 1.5e-27 96.4 0.1 2.6e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PXF41619.1 - 1.3e-05 25.4 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.20 PXF41619.1 - 0.06 12.9 0.1 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain rhaM PF05336.13 PXF41622.1 - 4.4e-21 75.0 0.3 5e-21 74.8 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF3022 PF11226.8 PXF41622.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) LON_substr_bdg PF02190.16 PXF41623.1 - 2.7e-20 73.2 0.0 4.5e-20 72.4 0.0 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain CLTH PF10607.9 PXF41624.1 - 4.1e-30 104.6 2.7 6.7e-30 103.9 2.7 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 PXF41624.1 - 2.1e-07 30.9 0.2 4.8e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PXF41624.1 - 0.0039 17.5 0.2 0.012 15.9 0.2 1.9 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 PXF41624.1 - 0.0058 16.0 0.2 0.0058 16.0 0.2 1.9 3 0 0 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.6 PXF41624.1 - 0.016 15.2 1.2 0.036 14.0 1.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RibD_C PF01872.17 PXF41625.1 - 1.1e-40 139.6 0.0 1.6e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 PXF41625.1 - 4.8e-22 77.8 0.1 9.7e-22 76.8 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF41625.1 - 1.4e-11 44.3 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 PXF41625.1 - 0.21 11.5 0.1 0.47 10.3 0.1 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Thioesterase PF00975.20 PXF41626.1 - 0.051 13.7 0.9 0.076 13.1 0.8 1.3 1 1 0 1 1 1 0 Thioesterase domain ERG4_ERG24 PF01222.17 PXF41627.1 - 3.2e-84 283.2 16.0 3.9e-84 282.9 16.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 PXF41627.1 - 1.7e-05 24.5 4.5 1.7e-05 24.4 1.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ELMO_CED12 PF04727.13 PXF41628.1 - 5e-31 108.2 0.0 7.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PCNA_N PF00705.18 PXF41629.1 - 2.5e-47 159.7 1.5 3.8e-47 159.1 1.5 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 PXF41629.1 - 3.2e-37 127.6 0.1 5.5e-36 123.6 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 PXF41629.1 - 2.8e-07 29.9 0.6 2.8e-05 23.3 0.6 2.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 PXF41629.1 - 8.8e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 PXF41629.1 - 0.035 13.2 0.0 0.16 11.1 0.0 2.2 1 1 0 1 1 1 0 Hus1-like protein PB1 PF00564.24 PXF41629.1 - 0.041 13.8 0.2 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 PB1 domain NPV_P10 PF05531.12 PXF41633.1 - 0.26 11.8 0.8 3.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SNO PF01174.19 PXF41635.1 - 1e-51 175.5 0.1 1.2e-51 175.3 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 PXF41635.1 - 1.7e-08 34.3 0.1 3.2e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 PXF41635.1 - 8.9e-06 25.5 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 PXF41635.1 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 PXF41635.1 - 0.0021 17.9 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Ank_2 PF12796.7 PXF41636.1 - 5.1e-25 87.9 4.9 1.2e-15 57.8 1.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF41636.1 - 3.2e-23 81.8 3.2 2.9e-10 40.5 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PXF41636.1 - 1.3e-17 63.3 3.3 1.2e-06 28.7 0.4 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PXF41636.1 - 1e-16 60.7 2.2 1.6e-08 34.7 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF41636.1 - 4.3e-13 48.2 0.1 0.00011 22.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Epimerase PF01370.21 PXF41638.1 - 5.1e-27 94.9 0.0 1.5e-26 93.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF41638.1 - 4.1e-21 75.7 0.0 1.2e-20 74.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PXF41638.1 - 1.4e-05 24.4 0.0 0.023 13.8 0.0 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PXF41638.1 - 0.0022 17.0 0.0 0.0048 15.9 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.14 PXF41638.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_transf_4 PF13439.6 PXF41638.1 - 0.008 16.2 0.1 0.44 10.5 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Pyr_redox_2 PF07992.14 PXF41638.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 PXF41639.1 - 2.9e-55 186.3 0.3 3.4e-55 186.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF41639.1 - 1.7e-32 112.2 0.1 2.8e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF41639.1 - 1.1e-20 73.8 0.1 1.4e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PXF41639.1 - 2e-07 31.1 0.0 2.9e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PXF41639.1 - 2.2e-05 23.9 0.1 2.7e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PXF41639.1 - 0.00018 21.0 0.1 0.00061 19.3 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PXF41639.1 - 0.00042 19.9 0.4 0.0016 18.0 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF41639.1 - 0.0015 18.4 0.9 0.11 12.4 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PXF41639.1 - 0.0039 17.6 0.1 0.0081 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PXF41639.1 - 0.026 14.2 0.1 0.051 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PXF41639.1 - 0.027 15.0 0.1 0.094 13.2 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PXF41639.1 - 0.031 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF41639.1 - 0.053 13.8 0.0 0.31 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 PXF41639.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 PXF41639.1 - 0.088 12.3 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 PXF41639.1 - 0.11 11.6 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain G-alpha PF00503.20 PXF41639.1 - 0.22 10.6 1.3 11 5.1 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit HU-CCDC81_bac_2 PF18175.1 PXF41640.1 - 0.076 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Caskin-tail PF16632.5 PXF41640.1 - 0.36 11.3 4.4 0.38 11.2 0.2 2.6 2 1 0 2 2 2 0 C-terminal region of Caskin Lipase_GDSL_2 PF13472.6 PXF41641.1 - 0.004 17.6 0.0 0.0051 17.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AbfS_sensor PF18225.1 PXF41641.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain F-box-like PF12937.7 PXF41642.1 - 1.6e-07 31.1 0.7 1.6e-07 31.1 0.7 2.1 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 PXF41642.1 - 2.7e-05 24.0 0.1 4.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 PXF41642.1 - 0.00019 21.2 0.9 0.00039 20.2 0.3 1.9 2 0 0 2 2 2 1 F-box domain Kelch_4 PF13418.6 PXF41644.1 - 1.1e-27 95.8 15.9 1.2e-07 31.6 0.1 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF41644.1 - 1.6e-19 69.7 11.2 3.7e-05 23.9 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF41644.1 - 1.3e-17 63.3 8.8 0.00082 19.6 0.0 6.6 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PXF41644.1 - 4.1e-17 61.5 5.6 0.0056 16.2 0.0 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PXF41644.1 - 5.2e-13 48.7 6.5 0.071 13.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif zf-C3HC4_3 PF13920.6 PXF41644.1 - 4e-11 42.6 9.8 7.4e-11 41.7 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.15 PXF41644.1 - 3.6e-09 36.3 9.9 0.029 14.4 0.0 6.2 6 0 0 6 6 6 3 Kelch motif WW PF00397.26 PXF41644.1 - 0.0016 18.5 0.6 0.0016 18.5 0.6 3.4 3 0 0 3 3 3 1 WW domain Prok-RING_4 PF14447.6 PXF41644.1 - 0.02 14.8 10.6 0.042 13.7 10.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PXF41644.1 - 0.029 14.7 12.0 0.064 13.6 12.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 PXF41644.1 - 0.03 14.2 12.1 0.058 13.3 12.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF41644.1 - 0.38 10.7 11.2 0.76 9.8 11.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 PXF41644.1 - 5.8 6.8 8.7 12 5.8 8.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PseudoU_synth_2 PF00849.22 PXF41646.1 - 2e-29 102.8 0.0 3.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PXF41646.1 - 7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain SF1-HH PF16275.5 PXF41647.1 - 8.9e-19 67.9 2.1 8.9e-19 67.9 2.1 1.9 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 PXF41647.1 - 7e-05 22.6 0.2 0.00012 21.8 0.2 1.4 1 0 0 1 1 1 1 KH domain Formyl_trans_N PF00551.19 PXF41648.1 - 1.5e-36 125.8 0.0 2e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PXF41648.1 - 2.8e-15 56.3 0.0 7.8e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain FabA PF07977.13 PXF41649.1 - 2.3e-34 118.0 0.0 3.5e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 PXF41649.1 - 0.0013 18.2 0.1 0.0065 16.0 0.0 1.9 1 1 1 2 2 2 1 MaoC like domain SIP1 PF04938.12 PXF41650.1 - 1.3e-37 129.7 0.0 1.6e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) ABATE PF07336.11 PXF41650.1 - 0.05 14.3 6.2 0.17 12.5 2.4 2.5 2 1 0 2 2 2 0 Putative stress-induced transcription regulator PDT PF00800.18 PXF41651.1 - 1.6e-57 194.3 0.1 2.7e-57 193.5 0.1 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 PXF41651.1 - 0.00018 21.2 0.1 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 ACT domain RRM_1 PF00076.22 PXF41652.1 - 9.1e-12 44.6 0.1 1.8e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 PXF41652.1 - 4.2e-05 23.4 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain RBM39linker PF15519.6 PXF41652.1 - 0.33 12.1 5.1 0.17 13.0 0.8 2.6 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein HSCB_C PF07743.13 PXF41653.1 - 1.3e-16 60.8 0.1 3.2e-16 59.6 0.0 1.7 2 1 1 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 PXF41653.1 - 1.6e-09 37.7 0.4 3e-09 36.9 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain YolD PF08863.10 PXF41653.1 - 0.015 15.3 0.1 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 YolD-like protein Vta1 PF04652.16 PXF41654.1 - 8.6e-41 139.3 0.3 2e-40 138.1 0.3 1.6 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 PXF41654.1 - 7.2e-15 54.4 0.8 1.7e-14 53.2 0.8 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain RNA12 PF10443.9 PXF41654.1 - 0.022 13.5 1.2 0.033 12.9 1.2 1.2 1 0 0 1 1 1 0 RNA12 protein MAJIN PF15077.6 PXF41654.1 - 0.029 14.2 6.3 0.05 13.4 1.2 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein Presenilin PF01080.17 PXF41654.1 - 0.12 11.1 4.0 0.17 10.6 4.0 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 PXF41654.1 - 0.13 12.4 2.9 0.29 11.3 2.9 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.11 PXF41654.1 - 0.14 11.5 1.1 0.24 10.8 1.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2052 PF09747.9 PXF41654.1 - 0.24 11.5 14.0 2.4 8.2 12.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 PXF41654.1 - 0.29 10.9 6.8 0.53 10.1 6.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 PXF41654.1 - 0.55 10.3 6.8 1.1 9.2 6.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIP PF07454.11 PXF41654.1 - 0.96 8.9 6.1 1.6 8.1 6.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spore_coat_CotO PF14153.6 PXF41654.1 - 1.1 9.1 15.9 2.5 8.0 15.9 1.5 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 PXF41654.1 - 5 5.3 6.6 8.1 4.6 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 PXF41654.1 - 6.1 6.6 11.0 42 3.8 8.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CobT PF06213.12 PXF41654.1 - 7.2 5.9 19.4 2.1 7.7 15.9 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PhyH PF05721.13 PXF41655.1 - 5.7e-46 157.4 0.3 8.7e-46 156.8 0.3 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 PXF41655.1 - 0.021 15.2 0.1 0.055 13.9 0.0 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase POT1 PF02765.17 PXF41658.1 - 1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 CDC24_OB3 PF17244.2 PXF41658.1 - 0.089 12.5 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Myc-LZ PF02344.15 PXF41658.1 - 0.12 12.5 0.4 0.34 11.1 0.4 1.7 1 0 0 1 1 1 0 Myc leucine zipper domain Ebp2 PF05890.12 PXF41659.1 - 1.5e-41 142.7 30.3 1.9e-41 142.4 30.3 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Transposase_21 PF02992.14 PXF41662.1 - 1.7e-09 37.3 0.0 3.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 C2 PF00168.30 PXF41664.1 - 0.0012 19.2 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 C2 domain TTR-52 PF01060.23 PXF41667.1 - 0.012 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family TatD_DNase PF01026.21 PXF41668.1 - 0.00088 18.7 0.0 23 4.3 0.0 4.1 4 0 0 4 4 4 1 TatD related DNase PapC_C PF13953.6 PXF41668.1 - 0.0059 16.4 0.1 0.57 10.0 0.0 3.5 3 0 0 3 3 3 1 PapC C-terminal domain Vault_4 PF17796.1 PXF41668.1 - 0.0067 16.5 0.9 15 5.8 0.0 3.9 4 0 0 4 4 4 1 Major Vault Protein repeat domain RecT PF03837.14 PXF41668.1 - 0.49 9.8 1.8 8.5 5.8 0.0 3.1 4 0 0 4 4 4 0 RecT family PSI_PsaE PF02427.17 PXF41668.1 - 0.82 9.4 5.0 9.3 6.0 0.1 3.9 4 0 0 4 4 4 0 Photosystem I reaction centre subunit IV / PsaE Pilin_PilX PF11530.8 PXF41668.1 - 1.1 9.2 3.5 1.4 8.8 0.1 2.8 4 0 0 4 4 4 0 Minor type IV pilin, PilX InPase PF18823.1 PXF41668.1 - 4.3 7.0 7.7 52 3.5 0.2 3.6 4 0 0 4 4 4 0 Inorganic Pyrophosphatase TatD_DNase PF01026.21 PXF41669.1 - 0.016 14.6 0.0 21 4.4 0.0 3.6 4 0 0 4 4 4 0 TatD related DNase DUF1905 PF08922.11 PXF41669.1 - 0.062 13.4 0.6 86 3.3 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1905) DUF5072 PF16807.5 PXF41669.1 - 0.1 12.6 0.0 79 3.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5072) PSI_PsaE PF02427.17 PXF41669.1 - 0.12 12.0 5.0 8 6.2 0.1 4.0 4 0 0 4 4 4 0 Photosystem I reaction centre subunit IV / PsaE NusB PF01029.18 PXF41669.1 - 0.21 11.8 0.0 21 5.3 0.0 2.7 3 0 0 3 3 3 0 NusB family InPase PF18823.1 PXF41669.1 - 3.3 7.4 7.7 54 3.4 0.2 3.6 4 0 0 4 4 4 0 Inorganic Pyrophosphatase VWA PF00092.28 PXF41670.1 - 2.6e-16 60.4 0.0 3.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF41670.1 - 8.6e-06 26.4 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF41670.1 - 0.00057 19.2 0.0 0.0036 16.6 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) VWA PF00092.28 PXF41671.1 - 4e-09 36.9 0.0 4.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF41671.1 - 4e-05 24.2 0.0 0.0001 22.9 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Methyltransf_31 PF13847.6 PXF41672.1 - 4.6e-17 62.2 0.0 7.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41672.1 - 2.2e-14 53.9 0.0 4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41672.1 - 3.6e-14 53.3 0.0 6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41672.1 - 5.4e-11 43.0 0.1 3.6e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41672.1 - 5.9e-11 42.5 0.0 1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF41672.1 - 4.7e-07 29.5 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PXF41672.1 - 1.4e-06 27.8 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 PXF41672.1 - 2.9e-05 23.6 0.0 5.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 PXF41672.1 - 5.1e-05 22.7 0.0 8.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 PXF41672.1 - 0.0017 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 PXF41672.1 - 0.035 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 PXF41672.1 - 0.051 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 PXF41672.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 PXF41672.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 PXF41672.1 - 0.14 13.1 0.0 0.35 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 PXF41673.1 - 9.6e-64 215.9 0.0 1.1e-63 215.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF41673.1 - 1.8e-48 165.2 0.1 2.2e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PXF41673.1 - 2.3e-17 63.0 0.3 2.5e-16 59.6 0.3 2.4 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 PXF41673.1 - 8.9e-17 61.0 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PXF41673.1 - 1.5e-16 60.4 0.0 6.4e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PXF41673.1 - 1.2e-15 57.4 0.0 1.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PXF41673.1 - 0.0003 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ATP-synt_ab PF00006.25 PXF41674.1 - 7.3e-68 228.4 0.0 1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PXF41674.1 - 8.2e-13 48.7 0.5 1.4e-12 47.9 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_hydro_77 PF02446.17 PXF41675.1 - 1.3e-139 466.0 5.9 1.9e-139 465.6 5.9 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 PXF41675.1 - 1.1e-16 60.5 0.0 2e-09 37.2 0.0 2.9 2 0 0 2 2 2 2 Starch binding domain MCR_C PF04609.12 PXF41675.1 - 0.079 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C DUF2465 PF10239.9 PXF41676.1 - 8.3e-32 110.7 0.2 1e-31 110.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) MRP-L28 PF09812.9 PXF41676.1 - 0.0072 16.5 2.9 0.51 10.5 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 RNA_lig_T4_1 PF09511.10 PXF41676.1 - 0.062 13.1 0.5 0.079 12.8 0.5 1.2 1 0 0 1 1 1 0 RNA ligase Maelstrom PF13017.6 PXF41676.1 - 0.11 12.1 1.5 0.13 11.9 0.4 1.6 1 1 1 2 2 2 0 piRNA pathway germ-plasm component AlkA_N PF06029.11 PXF41677.1 - 0.032 14.5 2.8 0.053 13.8 2.8 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain Trm112p PF03966.16 PXF41678.1 - 2.9e-07 31.0 0.0 4.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein DEAD PF00270.29 PXF41679.1 - 1.3e-34 119.5 0.8 3.8e-34 118.0 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF41679.1 - 3.7e-25 88.4 0.7 1.2e-24 86.8 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PXF41679.1 - 0.01 16.2 0.6 0.023 15.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 PXF41680.1 - 2.2e-08 34.1 7.3 5.6e-07 29.7 1.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF41680.1 - 1.2e-05 25.8 13.3 0.00058 20.5 0.8 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF41680.1 - 5.6e-05 23.4 16.0 0.00012 22.3 1.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 PXF41680.1 - 0.018 14.9 2.8 0.12 12.2 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 PXF41680.1 - 0.023 15.0 4.0 0.25 11.7 4.3 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PXF41680.1 - 0.029 14.6 0.6 0.029 14.6 0.6 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PXF41680.1 - 0.081 12.9 0.1 0.081 12.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 PXF41680.1 - 0.089 13.3 4.3 0.29 11.6 0.1 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_ZIC PF18366.1 PXF41680.1 - 0.18 11.9 2.7 0.82 9.8 0.1 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain HNH PF01844.23 PXF41680.1 - 0.25 11.6 2.0 13 6.1 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_2 PF12756.7 PXF41680.1 - 0.54 10.6 3.4 0.82 10.0 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BTB PF00651.31 PXF41682.1 - 1.5e-23 83.1 2.4 3.8e-23 81.8 0.5 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PXF41682.1 - 4.1e-20 71.8 2.6 8.5e-20 70.8 0.3 2.5 3 0 0 3 3 3 1 BTB And C-terminal Kelch MATH PF00917.26 PXF41682.1 - 7.2e-08 32.6 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 MATH domain Y_phosphatase3 PF13350.6 PXF41683.1 - 3.1e-31 109.1 0.0 4.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PXF41683.1 - 0.22 11.0 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Frag1 PF10277.9 PXF41685.1 - 0.00031 20.3 5.3 0.001 18.7 5.3 1.9 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3934 PF13070.6 PXF41685.1 - 0.3 11.6 3.1 0.58 10.7 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) RSN1_7TM PF02714.15 PXF41686.1 - 1.9e-54 184.9 15.8 1.9e-54 184.9 15.8 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PXF41686.1 - 2.2e-26 92.5 0.9 2.2e-26 92.5 0.9 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PXF41686.1 - 2.5e-15 57.1 0.1 4e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4663 PF15668.5 PXF41686.1 - 0.01 15.0 0.7 0.017 14.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4663) AKNA PF12443.8 PXF41686.1 - 0.47 11.1 2.0 1.1 9.9 0.4 2.3 3 0 0 3 3 3 0 AT-hook-containing transcription factor Inhibitor_I53 PF11714.8 PXF41687.1 - 0.13 12.5 0.4 0.24 11.6 0.4 1.3 1 0 0 1 1 1 0 Thrombin inhibitor Madanin RPN1_RPN2_N PF17781.1 PXF41688.1 - 1.5e-104 349.7 0.0 2.3e-104 349.1 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 PXF41688.1 - 1.9e-27 95.1 0.0 4.1e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 PXF41688.1 - 2.2e-24 84.6 11.8 9.4e-08 32.1 0.2 7.3 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PXF41688.1 - 0.0036 17.7 7.3 0.51 10.8 0.3 4.4 5 1 1 6 6 6 2 HEAT repeats Phage_TAC_11 PF11836.8 PXF41688.1 - 0.041 14.0 0.2 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 IFRD PF05004.13 PXF41688.1 - 6.8 5.7 6.1 0.86 8.6 0.0 2.5 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) cwf21 PF08312.12 PXF41690.1 - 3e-06 27.3 0.8 5.5e-06 26.4 0.8 1.4 1 0 0 1 1 1 1 cwf21 domain Sulfotransfer_3 PF13469.6 PXF41692.1 - 0.022 15.1 0.4 0.1 13.0 0.1 2.2 2 0 0 2 2 2 0 Sulfotransferase family Sulfotransfer_1 PF00685.27 PXF41693.1 - 3.1e-20 72.8 0.0 5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PXF41693.1 - 8.2e-06 26.4 0.0 0.018 15.4 0.0 3.3 1 1 1 2 2 2 2 Sulfotransferase family Codanin-1_C PF15296.6 PXF41694.1 - 3.2 7.9 8.0 0.29 11.2 0.5 2.9 3 0 0 3 3 3 0 Codanin-1 C-terminus Aconitase_C PF00694.19 PXF41696.1 - 1.6e-16 60.8 0.0 3.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 PXF41696.1 - 0.0013 18.4 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus CRAL_TRIO PF00650.20 PXF41697.1 - 2.9e-28 98.6 0.0 4e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PXF41697.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PXF41697.1 - 0.002 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AA_permease PF00324.21 PXF41699.1 - 0.0061 15.2 1.8 0.01 14.5 1.9 1.4 1 1 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 PXF41699.1 - 0.36 11.3 2.6 0.44 11.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4407 PF14362.6 PXF41699.1 - 0.36 10.1 4.5 0.42 9.9 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Malectin PF11721.8 PXF41700.1 - 1.7e-16 60.8 0.0 6.2e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Malectin domain TIG PF01833.24 PXF41700.1 - 4.5e-13 49.1 22.9 3e-08 33.6 3.9 4.4 4 0 0 4 4 4 2 IPT/TIG domain Mucin-like PF16058.5 PXF41700.1 - 0.0063 16.6 139.3 0.48 10.5 76.1 3.0 1 1 1 2 2 2 2 Mucin-like Bestrophin PF01062.21 PXF41702.1 - 1.5e-85 287.2 20.2 4.3e-21 75.6 0.7 5.2 5 0 0 5 5 5 5 Bestrophin, RFP-TM, chloride channel Ribosomal_L37e PF01907.19 PXF41705.1 - 0.055 13.6 1.9 0.12 12.6 1.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e zf-CCHC_4 PF14392.6 PXF41705.1 - 1.1 9.0 3.1 1.9 8.3 3.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 PXF41705.1 - 2 8.6 5.8 1.1 9.4 3.6 1.9 2 1 0 2 2 2 0 Zinc knuckle Methyltransf_31 PF13847.6 PXF41706.1 - 7.4e-11 42.1 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41706.1 - 1.9e-09 38.1 0.0 4.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41706.1 - 2.1e-08 34.7 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41706.1 - 4.2e-06 27.4 0.0 8.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF41706.1 - 7.7e-06 26.0 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 PXF41706.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 PXF41706.1 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF41706.1 - 0.0035 17.1 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 PXF41706.1 - 0.0053 16.1 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PXF41706.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain SSF PF00474.17 PXF41708.1 - 7e-25 87.7 17.2 9.6e-20 70.8 7.4 2.1 2 0 0 2 2 2 2 Sodium:solute symporter family Methyltransf_31 PF13847.6 PXF41709.1 - 5.1e-12 45.8 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41709.1 - 1.3e-10 41.8 0.0 2.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41709.1 - 6.3e-09 36.4 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF41709.1 - 2e-07 31.1 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41709.1 - 9.3e-07 29.5 0.0 1.7e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41709.1 - 5.5e-05 23.1 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 PXF41709.1 - 0.00028 20.4 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 PXF41709.1 - 0.0003 20.2 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PXF41709.1 - 0.00075 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.17 PXF41709.1 - 0.00092 18.4 0.0 0.0013 17.9 0.0 1.3 1 1 0 1 1 1 1 Fibrillarin MTS PF05175.14 PXF41709.1 - 0.0026 17.3 0.0 0.007 15.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 PXF41709.1 - 0.051 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CheR PF01739.18 PXF41709.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 PXF41709.1 - 0.11 11.9 0.1 0.3 10.5 0.0 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TehB WD40 PF00400.32 PXF41711.1 - 2.3e-07 31.4 6.2 0.019 15.8 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41711.1 - 0.016 15.5 0.1 3.6 7.9 0.1 3.5 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF41711.1 - 0.1 11.5 0.0 39 3.1 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 PXF41711.1 - 0.2 11.3 0.0 6.1 6.5 0.0 2.6 2 1 0 2 2 2 0 TUP1-like enhancer of split UPF0556 PF10572.9 PXF41714.1 - 4.7e-07 29.4 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Tau95 PF09734.9 PXF41715.1 - 1.9e-27 96.8 0.1 3.5e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 PXF41715.1 - 7.2e-07 29.4 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain RNA_pol_3_Rpc31 PF11705.8 PXF41715.1 - 0.16 12.2 18.3 0.39 10.9 18.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 PXF41715.1 - 0.32 10.4 16.6 0.69 9.3 16.6 1.5 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 PXF41715.1 - 0.61 8.5 4.9 1 7.7 4.9 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 PXF41715.1 - 0.64 8.2 13.0 1 7.6 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 PXF41715.1 - 1.1 7.3 18.0 2 6.5 18.0 1.3 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 PXF41715.1 - 5.8 7.2 6.4 22 5.3 4.5 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TFB6 PF17110.5 PXF41715.1 - 5.9 6.6 6.3 19 5.0 6.3 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 PXF41715.1 - 7.5 5.8 20.0 17 4.6 20.0 1.5 1 0 0 1 1 1 0 NOA36 protein zf-C2H2 PF00096.26 PXF41716.1 - 0.02 15.3 21.8 0.32 11.5 7.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 PXF41716.1 - 0.14 12.5 5.9 0.25 11.6 5.9 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 PXF41716.1 - 0.2 12.6 17.6 1.1 10.3 5.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger KAR9 PF08580.10 PXF41716.1 - 2.1 6.8 7.8 2.4 6.6 7.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF4551 PF15087.6 PXF41716.1 - 2.4 6.9 5.4 2.8 6.7 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2457 PF10446.9 PXF41716.1 - 2.6 7.1 10.9 3 6.9 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1995 PF09353.10 PXF41717.1 - 5.2e-18 65.8 0.5 1.9e-17 64.0 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) HopA1 PF17914.1 PXF41717.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 HopA1 effector protein family Pyridox_oxase_2 PF12766.7 PXF41718.1 - 1.4e-13 51.2 0.0 2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PXF41718.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 PXF41718.1 - 0.0035 16.9 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Myb_DNA-binding PF00249.31 PXF41719.1 - 3.1e-44 148.9 7.0 1.2e-12 47.8 0.2 4.2 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF41719.1 - 7.6e-37 125.4 1.4 1.1e-13 51.2 0.0 4.2 2 1 2 4 4 4 4 Myb-like DNA-binding domain SLIDE PF09111.10 PXF41719.1 - 5.9e-05 23.1 0.0 0.5 10.4 0.0 3.1 3 0 0 3 3 3 2 SLIDE Rap1_C PF11626.8 PXF41719.1 - 0.00016 21.7 0.7 0.78 9.9 0.1 3.2 2 1 1 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 PXF41719.1 - 0.0017 18.5 0.5 27 5.1 0.0 3.8 1 1 3 4 4 4 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 PXF41719.1 - 0.003 17.9 6.5 7.6 7.0 0.3 4.6 3 3 1 4 4 4 1 Myb/SANT-like DNA-binding domain MarR_2 PF12802.7 PXF41719.1 - 0.022 14.6 0.3 4.1 7.4 0.0 3.4 3 0 0 3 3 3 0 MarR family Atg29_N PF18388.1 PXF41719.1 - 0.055 13.3 0.4 5.4 6.9 0.0 3.2 4 0 0 4 4 4 0 Atg29 N-terminal domain Myb_DNA-bind_7 PF15963.5 PXF41719.1 - 0.066 13.1 0.0 1.3 8.9 0.0 2.8 4 0 0 4 4 4 0 Myb DNA-binding like SRP54 PF00448.22 PXF41720.1 - 8e-53 179.0 0.3 1.4e-52 178.2 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 PXF41720.1 - 3.8e-27 96.0 6.3 7.3e-27 95.0 6.3 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 PXF41720.1 - 3.9e-05 23.8 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 PXF41720.1 - 8e-05 21.7 0.2 0.00025 20.1 0.1 1.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 PXF41720.1 - 0.00053 20.0 0.0 0.0038 17.3 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 PXF41720.1 - 0.0026 17.5 0.1 0.0047 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PXF41720.1 - 0.0085 15.8 0.2 0.15 11.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 PXF41720.1 - 0.015 15.2 0.8 0.58 10.0 0.2 2.9 1 1 1 2 2 2 0 NTPase Fer4_NifH PF00142.18 PXF41720.1 - 0.076 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Longin PF13774.6 PXF41720.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain YkuI_C PF10388.9 PXF41720.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain PSK_trans_fac PF07704.11 PXF41720.1 - 0.82 10.5 6.0 0.72 10.7 0.4 2.9 2 0 0 2 2 2 0 Rv0623-like transcription factor Peptidase_C70 PF12385.8 PXF41721.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 DUF5330 PF17264.2 PXF41723.1 - 0.00097 19.1 1.9 0.0042 17.1 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5330) Sigma70_ner PF04546.13 PXF41723.1 - 0.013 15.4 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BNIP2 PF12496.8 PXF41723.1 - 0.019 15.4 0.1 0.023 15.1 0.1 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 NUP50 PF08911.11 PXF41723.1 - 0.063 13.9 0.5 0.11 13.1 0.5 1.4 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) PGA2 PF07543.12 PXF41723.1 - 0.1 12.6 3.4 0.19 11.7 3.4 1.6 1 1 0 1 1 1 0 Protein trafficking PGA2 DBINO PF13892.6 PXF41723.1 - 0.21 11.9 6.4 0.26 11.6 5.5 1.5 1 1 1 2 2 2 0 DNA-binding domain DUF5089 PF17002.5 PXF41723.1 - 0.3 11.0 6.0 0.83 9.5 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) AIM3 PF17096.5 PXF41723.1 - 1.1 10.3 13.6 0.53 11.2 9.9 2.3 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 CAP18_C PF12153.8 PXF41723.1 - 8.2 6.4 15.8 4.9 7.1 8.2 2.3 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) DUF3506 PF12014.8 PXF41724.1 - 0.098 12.7 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) DUF5330 PF17264.2 PXF41725.1 - 0.0006 19.8 1.7 0.0031 17.5 0.2 2.3 1 1 1 2 2 2 1 Family of unknown function (DUF5330) BNIP2 PF12496.8 PXF41725.1 - 0.018 15.5 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Sigma70_ner PF04546.13 PXF41725.1 - 0.028 14.3 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SseC PF04888.12 PXF41725.1 - 0.093 12.3 1.3 0.14 11.8 1.3 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PGA2 PF07543.12 PXF41725.1 - 0.11 12.4 4.0 0.071 13.1 1.7 1.7 1 1 1 2 2 2 0 Protein trafficking PGA2 DUF5089 PF17002.5 PXF41725.1 - 0.16 11.8 5.1 0.31 10.9 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) DBINO PF13892.6 PXF41725.1 - 0.17 12.2 6.7 0.18 12.1 5.6 1.5 1 1 1 2 2 2 0 DNA-binding domain AIM3 PF17096.5 PXF41725.1 - 1.8 9.6 14.7 0.87 10.6 10.9 2.3 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Cyclin PF08613.11 PXF41726.1 - 3.7e-28 98.9 0.1 5.5e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF41726.1 - 3.4e-08 33.3 0.4 7.4e-08 32.2 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain N6_N4_Mtase PF01555.18 PXF41728.1 - 0.00076 19.2 0.0 0.003 17.3 0.0 2.0 2 1 0 2 2 2 1 DNA methylase PHD_2 PF13831.6 PXF41728.1 - 0.19 11.3 1.2 0.4 10.3 1.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-C2H2 PF00096.26 PXF41729.1 - 6.3e-07 29.5 14.0 0.0019 18.6 3.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF41729.1 - 5.7e-05 23.6 12.1 0.44 11.5 3.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 PXF41729.1 - 0.0017 18.6 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF41729.1 - 0.0078 16.5 0.0 3.8 7.9 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PXF41729.1 - 0.0079 15.9 4.9 1.2 8.9 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 PXF41729.1 - 0.016 15.6 0.5 0.016 15.6 0.5 3.6 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 PXF41729.1 - 0.03 14.9 4.9 7.6 7.2 0.0 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 PXF41729.1 - 0.33 11.7 3.9 0.15 12.7 1.5 1.7 2 0 0 2 2 2 0 TRAF-type zinc finger Med7 PF05983.11 PXF41730.1 - 2e-30 106.3 3.9 2e-30 106.3 3.9 2.3 2 1 0 2 2 2 1 MED7 protein MIS13 PF08202.11 PXF41730.1 - 0.0042 16.4 0.5 0.0052 16.1 0.5 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Mer2 PF09074.10 PXF41730.1 - 0.036 13.9 0.2 0.056 13.3 0.2 1.3 1 0 0 1 1 1 0 Mer2 5_nucleotid PF05761.14 PXF41730.1 - 0.052 12.5 0.1 0.066 12.1 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family MyTH4 PF00784.17 PXF41730.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 MyTH4 domain RuvX PF03652.15 PXF41731.1 - 2e-26 93.0 0.0 2.9e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction resolvase DAP_epimerase PF01678.19 PXF41732.1 - 1.3e-50 170.6 0.1 3.3e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase Pro_racemase PF05544.11 PXF41732.1 - 2.7e-05 23.4 0.1 7.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Proline racemase DHODB_Fe-S_bind PF10418.9 PXF41732.1 - 0.038 13.8 1.2 0.14 12.0 1.2 2.0 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B GTP1_OBG PF01018.22 PXF41733.1 - 1.5e-54 183.8 8.0 2.5e-54 183.1 8.0 1.4 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 PXF41733.1 - 4e-23 81.7 0.0 5e-22 78.1 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF1967 PF09269.11 PXF41733.1 - 3.3e-19 68.6 0.1 6.7e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) FeoB_N PF02421.18 PXF41733.1 - 1.5e-09 37.6 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 PXF41733.1 - 0.015 15.0 0.2 0.12 12.1 0.0 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain Arf PF00025.21 PXF41733.1 - 0.055 12.9 0.2 0.59 9.6 0.2 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 PXF41733.1 - 0.12 12.9 0.2 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 PXF41733.1 - 0.13 12.3 0.1 2.4 8.2 0.1 2.5 1 1 0 1 1 1 0 Dynamin family An_peroxidase PF03098.15 PXF41735.1 - 9.4e-07 27.8 0.0 9.8e-07 27.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF3377 PF11857.8 PXF41736.1 - 1.5 8.8 4.2 0.46 10.4 0.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF3952 PF13130.6 PXF41737.1 - 0.066 13.4 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) DUF3176 PF11374.8 PXF41737.1 - 0.08 13.2 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) RcsC PF09456.10 PXF41739.1 - 0.079 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) MHB PF16525.5 PXF41740.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Haemophore, haem-binding ADH_zinc_N_2 PF13602.6 PXF41742.1 - 7.7e-14 52.9 0.0 2.8e-13 51.1 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PXF41742.1 - 8.1e-09 35.5 0.4 1.5e-08 34.7 0.4 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PXF41742.1 - 1.9e-07 30.9 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FUN14 PF04930.15 PXF41743.1 - 2.5e-18 66.3 0.1 3.2e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 FUN14 family SPC12 PF06645.13 PXF41743.1 - 0.014 15.4 0.6 0.03 14.4 0.6 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HJURP_mid PF12346.8 PXF41744.1 - 0.0042 17.5 0.5 0.0042 17.5 0.5 2.6 2 1 0 2 2 2 1 Holliday junction recognition protein-associated repeat GREB1 PF15782.5 PXF41744.1 - 3 4.8 5.7 4 4.4 5.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PhyH PF05721.13 PXF41745.1 - 1.5e-08 35.2 0.0 3.1e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Gal-3-0_sulfotr PF06990.11 PXF41746.1 - 4.8e-09 35.6 0.4 8.4e-09 34.8 0.4 1.3 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PXF41746.1 - 3.1e-06 27.3 1.2 3.1e-06 27.3 1.2 1.7 1 1 1 2 2 2 1 Sulfotransferase family Copine PF07002.16 PXF41747.1 - 6e-56 189.3 0.0 8e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 PXF41747.1 - 3.6e-24 85.0 0.0 3.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain WW PF00397.26 PXF41747.1 - 3e-09 36.8 0.9 7.3e-09 35.6 0.9 1.7 1 0 0 1 1 1 1 WW domain vWA-TerF-like PF10138.9 PXF41747.1 - 0.00047 20.3 0.0 0.00074 19.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2854 PF11016.8 PXF41748.1 - 1.3e-46 158.1 0.0 1.7e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) DUF1664 PF07889.12 PXF41749.1 - 2e-06 27.9 46.2 0.049 13.7 0.5 8.6 5 2 5 10 10 10 5 Protein of unknown function (DUF1664) IMPa_helical PF18642.1 PXF41749.1 - 0.015 15.7 5.6 0.17 12.3 0.5 3.9 3 0 0 3 3 3 0 Immunomodulating metalloprotease helical domain ATG16 PF08614.11 PXF41749.1 - 0.032 14.5 126.0 0.085 13.1 5.3 8.4 3 2 6 9 9 9 0 Autophagy protein 16 (ATG16) WD40_alt PF14077.6 PXF41749.1 - 0.12 12.2 0.4 2.6 8.0 0.1 3.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif CENP-F_leu_zip PF10473.9 PXF41749.1 - 0.2 11.7 100.0 0.095 12.7 14.3 9.7 3 2 7 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 PXF41749.1 - 0.39 9.3 65.2 0.026 13.2 13.3 4.3 2 1 2 4 4 4 0 AAA domain TRAF_BIRC3_bd PF16673.5 PXF41749.1 - 8.4 6.3 19.8 0.24 11.2 0.6 5.3 4 1 1 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain DnaI_N PF07319.11 PXF41750.1 - 0.0013 19.4 0.4 0.014 16.0 0.0 2.0 1 1 1 2 2 2 1 Primosomal protein DnaI N-terminus YccV-like PF08755.11 PXF41751.1 - 3.5e-12 46.7 0.0 5.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 PXF41751.1 - 2.3e-07 30.3 1.4 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 2 UvrB/uvrC motif ECH_1 PF00378.20 PXF41752.1 - 1.8e-35 122.5 0.2 2.2e-35 122.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PXF41752.1 - 1.5e-25 90.4 0.1 1.8e-25 90.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RecQ_Zn_bind PF16124.5 PXF41752.1 - 0.023 15.4 0.1 0.054 14.2 0.1 1.6 1 0 0 1 1 1 0 RecQ zinc-binding ResIII PF04851.15 PXF41752.1 - 0.055 13.5 0.1 0.18 11.8 0.1 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PK PF00224.21 PXF41753.1 - 8.2e-143 475.5 7.7 1.2e-142 474.9 7.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PXF41753.1 - 2e-30 105.4 0.4 6.4e-30 103.8 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PXF41753.1 - 0.0081 15.3 1.1 0.02 14.0 0.7 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Phage_fiber_2 PF03406.13 PXF41753.1 - 0.096 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat Copine PF07002.16 PXF41754.1 - 2.3e-58 197.3 0.0 3.9e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 PXF41754.1 - 1e-16 61.1 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 PXF41754.1 - 2.4e-06 27.8 0.0 4.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus CBP_BcsF PF11120.8 PXF41754.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF PhyH PF05721.13 PXF41756.1 - 0.00015 22.1 0.1 0.00032 21.0 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EMP24_GP25L PF01105.24 PXF41757.1 - 5.6e-17 62.3 0.0 7.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Laminin_II PF06009.12 PXF41757.1 - 0.022 14.7 0.6 0.22 11.5 0.5 2.0 2 0 0 2 2 2 0 Laminin Domain II EMP24_GP25L PF01105.24 PXF41758.1 - 7.1e-15 55.4 0.0 8.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.16 PXF41759.1 - 2e-17 62.9 0.0 2.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Orbi_VP4 PF05059.12 PXF41759.1 - 0.038 12.0 0.0 0.047 11.7 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Peptidase_C27 PF05407.12 PXF41761.1 - 0.074 13.1 0.2 1 9.4 0.0 2.6 3 0 0 3 3 3 0 Rubella virus endopeptidase CNOT1_TTP_bind PF16417.5 PXF41762.1 - 1.1e-18 67.1 0.1 2.2e-18 66.1 0.0 1.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 PXF41762.1 - 4.9e-06 26.7 0.3 8.8e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PPR_2 PF13041.6 PXF41762.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family CNOT1_CAF1_bind PF16415.5 PXF41763.1 - 2.8e-70 236.2 1.8 3.9e-70 235.7 1.8 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Peptidase_C27 PF05407.12 PXF41766.1 - 0.078 13.1 0.2 1 9.4 0.0 2.6 3 0 0 3 3 3 0 Rubella virus endopeptidase DHO_dh PF01180.21 PXF41768.1 - 2.1e-95 319.4 0.0 2.5e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 PXF41768.1 - 0.024 14.1 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase FMN_dh PF01070.18 PXF41768.1 - 0.15 11.0 0.9 0.37 9.8 0.7 1.7 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Pkinase PF00069.25 PXF41769.1 - 1.1e-77 260.9 0.0 1.4e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41769.1 - 1.8e-40 138.9 0.0 2.2e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF41769.1 - 4e-07 29.6 0.0 2.1e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PXF41769.1 - 0.00017 20.5 0.0 0.00038 19.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase PH PF00169.29 PXF41769.1 - 0.00062 20.2 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PXF41769.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 PXF41769.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 PXF41769.1 - 0.03 13.8 0.2 0.059 12.9 0.2 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Mcp5_PH PF12814.7 PXF41769.1 - 0.093 12.8 0.0 0.27 11.4 0.0 1.8 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Haspin_kinase PF12330.8 PXF41769.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Orn_Arg_deC_N PF02784.16 PXF41770.1 - 1.6e-34 119.4 0.0 1.9e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PXF41770.1 - 5.2e-13 49.0 0.0 6.6e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 PXF41770.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain DUF5446 PF17522.2 PXF41772.1 - 0.0077 16.4 1.5 0.016 15.3 1.5 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5446) Peptidase_M3_N PF08439.10 PXF41772.1 - 0.05 13.9 0.2 0.097 13.0 0.2 1.5 1 0 0 1 1 1 0 Oligopeptidase F APG6_N PF17675.1 PXF41772.1 - 0.061 13.8 0.1 0.24 11.9 0.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region PRA1 PF03208.19 PXF41774.1 - 2.8e-24 85.4 0.9 3.7e-24 85.0 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein Mito_carr PF00153.27 PXF41775.1 - 2.6e-62 206.7 2.4 1.4e-22 79.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 PXF41776.1 - 1.7e-18 67.0 22.9 2.1e-18 66.7 22.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family MRP-L27 PF09809.9 PXF41777.1 - 5.7e-19 68.0 0.3 7.3e-19 67.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 CAC1F_C PF16885.5 PXF41778.1 - 0.017 14.9 0.2 0.018 14.7 0.2 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term 6PF2K PF01591.18 PXF41780.1 - 1.1e-75 253.8 0.0 1.5e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PXF41780.1 - 3.1e-35 121.6 0.0 5.9e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 PXF41780.1 - 3.5e-06 27.2 0.0 7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PXF41780.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 PXF41780.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 PXF41780.1 - 0.15 11.3 0.0 0.37 10.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Glyco_tran_28_C PF04101.16 PXF41781.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain QRPTase_C PF01729.19 PXF41782.1 - 1.7e-45 154.8 0.0 2.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 PXF41782.1 - 4.2e-13 49.1 0.0 1.3e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IMPDH PF00478.25 PXF41782.1 - 0.004 16.2 0.1 0.0045 16.0 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Vps35 PF03635.17 PXF41784.1 - 1.4e-173 579.2 1.8 1.7e-173 579.0 1.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DDHD PF02862.17 PXF41785.1 - 3.7e-23 82.9 0.0 2.5e-21 76.9 0.0 2.7 2 1 0 2 2 2 1 DDHD domain CUE PF02845.16 PXF41785.1 - 2.6e-07 30.2 0.0 5.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain NKAP PF15692.5 PXF41785.1 - 0.9 10.3 0.0 0.9 10.3 0.0 2.6 3 0 0 3 3 3 0 NF-kappa-B-activating protein Hint PF01079.20 PXF41786.1 - 2.5e-24 86.0 0.3 8.8e-24 84.2 0.3 1.8 1 1 0 1 1 1 1 Hint module Trypan_PARP PF05887.11 PXF41786.1 - 0.0019 18.2 1.8 0.0019 18.2 1.8 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Hint_2 PF13403.6 PXF41786.1 - 0.038 14.3 0.6 0.32 11.3 0.0 2.6 2 1 0 2 2 2 0 Hint domain FAM75 PF14650.6 PXF41786.1 - 0.047 13.2 11.2 0.087 12.4 11.2 1.5 1 0 0 1 1 1 0 FAM75 family zf-RING_2 PF13639.6 PXF41787.1 - 1.4e-10 41.3 6.4 2.5e-10 40.5 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF41787.1 - 3.3e-06 26.7 2.9 3.3e-06 26.7 2.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF41787.1 - 4.9e-05 23.5 7.5 4.9e-05 23.5 7.5 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF41787.1 - 0.00011 22.0 6.1 0.00024 20.9 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF41787.1 - 0.00026 20.8 4.4 0.00047 20.0 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF41787.1 - 0.0017 18.2 3.2 0.0028 17.5 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PXF41787.1 - 0.0019 18.3 4.3 0.0035 17.4 4.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.6 PXF41787.1 - 0.0059 16.6 1.7 0.0092 16.0 0.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF41787.1 - 0.0082 16.1 3.5 0.015 15.2 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UPF0561 PF10573.9 PXF41787.1 - 0.0093 16.1 0.1 0.0093 16.1 0.1 1.7 2 0 0 2 2 1 1 Uncharacterised protein family UPF0561 SPX PF03105.19 PXF41787.1 - 0.011 15.7 9.7 0.07 13.0 9.7 1.9 1 1 0 1 1 1 0 SPX domain FANCL_C PF11793.8 PXF41787.1 - 0.025 14.8 3.4 0.03 14.5 1.8 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Tim54 PF11711.8 PXF41787.1 - 0.049 12.4 1.1 0.075 11.8 1.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 PXF41787.1 - 0.055 11.4 0.2 0.077 10.9 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_holin_3_6 PF07332.11 PXF41787.1 - 0.069 13.2 5.7 0.84 9.7 0.9 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-ANAPC11 PF12861.7 PXF41787.1 - 0.091 12.8 4.3 0.39 10.8 4.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PXF41787.1 - 0.11 12.1 3.2 0.2 11.3 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rrn6 PF10214.9 PXF41787.1 - 0.39 9.1 19.8 0.028 12.9 1.2 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor SR-25 PF10500.9 PXF41787.1 - 0.64 9.6 24.4 0.25 10.9 14.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3341 PF11821.8 PXF41787.1 - 0.7 9.5 6.9 0.19 11.3 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Prok-RING_4 PF14447.6 PXF41787.1 - 1.1 9.2 5.7 4.4 7.2 5.5 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RR_TM4-6 PF06459.12 PXF41787.1 - 1.9 8.3 6.4 3.9 7.2 6.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2070 PF09843.9 PXF41787.1 - 2.6 6.2 11.5 3.6 5.8 11.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Orf78 PF06024.12 PXF41787.1 - 3.3 8.1 9.7 11 6.3 1.0 3.1 2 2 0 2 2 2 0 Orf78 (ac78) CPSF100_C PF13299.6 PXF41787.1 - 3.9 7.6 6.6 15 5.8 5.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 PXF41787.1 - 4.8 7.2 13.8 28 4.7 11.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 WD40 PF00400.32 PXF41788.1 - 7.3e-05 23.5 10.9 0.084 13.8 0.2 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Flp_C PF05202.12 PXF41789.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Recombinase Flp protein Bestrophin PF01062.21 PXF41790.1 - 5.7e-86 288.5 21.5 1.9e-19 70.2 0.0 5.2 5 0 0 5 5 5 5 Bestrophin, RFP-TM, chloride channel YhhN PF07947.14 PXF41791.1 - 0.049 13.2 1.7 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 YhhN family DUF3989 PF13150.6 PXF41791.1 - 0.12 12.2 1.4 0.19 11.5 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) OAD_gamma PF04277.13 PXF41792.1 - 5.4 7.7 10.6 0.71 10.5 5.0 2.2 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Lactamase_B PF00753.27 PXF41793.1 - 0.019 15.0 0.1 0.035 14.1 0.0 1.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF41793.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LRR_4 PF12799.7 PXF41794.1 - 0.0072 16.7 0.1 6.2 7.4 0.2 3.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Endostatin PF06482.11 PXF41794.1 - 0.028 13.9 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Glyco_trans_2_3 PF13632.6 PXF41795.1 - 6.7e-21 75.1 6.8 6.7e-21 75.1 6.8 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PXF41795.1 - 1.1e-11 45.1 0.1 1.6e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 PXF41795.1 - 0.63 8.6 3.9 0.86 8.1 3.9 1.2 1 0 0 1 1 1 0 Chitin synthase Retrotran_gag_2 PF14223.6 PXF41798.1 - 8.3e-10 38.5 0.0 8.5e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CDC37_C PF08564.10 PXF41798.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Cdc37 C terminal domain DUF383 PF04063.14 PXF41799.1 - 0.13 11.9 0.1 0.41 10.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF383) rve PF00665.26 PXF41800.1 - 2.5e-07 30.9 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 PXF41801.1 - 1.4e-09 38.4 10.6 0.061 14.2 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF41801.1 - 0.044 14.1 0.1 29 5.1 0.0 3.9 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain ABC1 PF03109.16 PXF41802.1 - 1.5e-07 31.6 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ABC1 family DNA_pol_B PF00136.21 PXF41805.1 - 0.00034 19.5 0.0 0.00036 19.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PXF41806.1 - 7.4e-07 28.6 0.0 8.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain AAA_23 PF13476.6 PXF41807.1 - 0.00047 20.7 0.2 0.00074 20.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain Spc7 PF08317.11 PXF41807.1 - 0.032 13.1 4.5 0.042 12.7 4.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 PXF41807.1 - 0.068 11.8 1.5 0.082 11.5 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4041 PF13250.6 PXF41807.1 - 0.079 12.8 0.1 0.47 10.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) DUF4200 PF13863.6 PXF41807.1 - 0.35 11.3 6.1 0.87 10.0 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) SNF2_N PF00176.23 PXF41808.1 - 3.3e-47 160.9 0.0 5.2e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 PXF41808.1 - 3.8e-06 26.7 8.2 7.6e-06 25.7 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF41808.1 - 2.2e-05 24.2 9.2 2.2e-05 24.2 9.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF41808.1 - 4.4e-05 23.7 9.5 0.00013 22.2 9.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF41808.1 - 0.00025 21.0 6.7 0.00072 19.5 6.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF41808.1 - 0.00029 20.7 9.6 0.00062 19.7 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PXF41808.1 - 0.00083 19.1 6.9 0.00083 19.1 6.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 PXF41808.1 - 0.0034 17.7 0.0 0.0097 16.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 PXF41808.1 - 0.024 14.5 7.4 0.092 12.6 7.2 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF41808.1 - 0.087 12.9 3.2 0.21 11.7 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Hydrolase PF00702.26 PXF41808.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ESP PF16590.5 PXF41808.1 - 0.12 12.7 0.2 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Exocrine gland-secreting peptide zf-Nse PF11789.8 PXF41808.1 - 0.15 11.9 1.2 0.47 10.3 1.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 PXF41808.1 - 0.23 11.7 9.6 0.54 10.5 9.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PXF41808.1 - 0.27 11.6 3.9 0.89 9.9 3.9 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Importin_rep_4 PF18808.1 PXF41808.1 - 1.3 9.4 3.9 10 6.5 0.0 3.1 3 0 0 3 3 3 0 Importin repeat F-box PF00646.33 PXF41809.1 - 1.6e-09 37.4 0.1 2.8e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF41809.1 - 6.8e-07 29.1 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 F-box-like UDG PF03167.19 PXF41810.1 - 6.4e-24 84.7 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2389 PF09493.10 PXF41811.1 - 5.8e-11 42.9 0.2 1e-10 42.1 0.2 1.4 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) DnaJ_CXXCXGXG PF00684.19 PXF41811.1 - 0.021 15.2 10.5 0.83 10.1 0.8 2.9 2 1 0 2 2 2 0 DnaJ central domain zf-C2H2_3 PF13878.6 PXF41812.1 - 0.26 11.1 0.2 0.26 11.1 0.2 3.4 2 2 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Gin PF10764.9 PXF41812.1 - 0.47 10.4 4.3 1.2 9.2 0.2 2.8 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin Ogr_Delta PF04606.12 PXF41812.1 - 1.5 8.9 7.9 0.37 10.8 0.8 2.7 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger MFS_1 PF07690.16 PXF41815.1 - 1.5e-20 73.4 71.3 2.8e-15 56.1 39.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF321 PF03778.13 PXF41815.1 - 0.037 13.7 0.1 0.73 9.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Transcrip_reg PF01709.20 PXF41816.1 - 1.8e-50 171.6 0.0 2.1e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF778 PF05608.12 PXF41817.1 - 3.7e-29 102.5 3.2 3.9e-15 56.7 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) NHL PF01436.21 PXF41817.1 - 0.16 12.1 1.4 12 6.2 0.0 2.6 2 0 0 2 2 2 0 NHL repeat Mo25 PF08569.11 PXF41818.1 - 1.2e-114 383.1 1.3 1.5e-114 382.8 1.3 1.0 1 0 0 1 1 1 1 Mo25-like PikAIV_N PF18605.1 PXF41818.1 - 0.034 13.7 0.1 0.088 12.4 0.1 1.8 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ras PF00071.22 PXF41819.1 - 4e-49 166.3 0.0 6.1e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF41819.1 - 6.1e-31 107.1 0.0 1.1e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF41819.1 - 5.5e-14 52.0 0.0 9.5e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family bZIP_1 PF00170.21 PXF41819.1 - 1.3e-09 38.0 15.6 1.3e-09 38.0 15.6 1.8 1 1 0 1 1 1 1 bZIP transcription factor MMR_HSR1 PF01926.23 PXF41819.1 - 9.6e-06 25.7 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase bZIP_2 PF07716.15 PXF41819.1 - 1e-05 25.5 15.6 1e-05 25.5 15.6 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Gtr1_RagA PF04670.12 PXF41819.1 - 9.4e-05 21.9 0.5 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PXF41819.1 - 0.00011 21.8 0.0 0.0092 15.5 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PXF41819.1 - 0.0041 17.5 0.3 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PXF41819.1 - 0.0042 17.4 0.2 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 PXF41819.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PXF41819.1 - 0.025 14.5 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 PXF41819.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PXF41819.1 - 0.043 13.6 0.1 11 5.8 0.0 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 PXF41819.1 - 0.14 12.7 1.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 PXF41819.1 - 0.14 11.9 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 PXF41819.1 - 0.14 12.1 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FAM76 PF16046.5 PXF41819.1 - 0.63 9.3 11.2 0.98 8.7 11.2 1.2 1 0 0 1 1 1 0 FAM76 protein AAA_23 PF13476.6 PXF41819.1 - 4 7.9 11.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Isy1 PF06246.12 PXF41820.1 - 3.3e-61 207.1 11.4 4.1e-61 206.8 11.4 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Nmad2 PF18753.1 PXF41820.1 - 0.0023 17.4 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotide modification associated domain 2 YolD PF08863.10 PXF41820.1 - 0.15 12.1 0.5 0.91 9.6 0.0 2.5 2 0 0 2 2 2 0 YolD-like protein XPG_I_2 PF12813.7 PXF41820.1 - 0.16 11.4 1.7 0.42 10.1 0.2 2.0 2 0 0 2 2 2 0 XPG domain containing Pep_deformylase PF01327.21 PXF41821.1 - 6.4e-48 162.4 0.0 8.8e-48 161.9 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase Phycobilisome PF00502.19 PXF41822.1 - 9.2e-07 28.9 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Phycobilisome protein Cuticle_1 PF08140.11 PXF41824.1 - 0.023 14.7 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Crustacean cuticle protein repeat LPMO_10 PF03067.15 PXF41825.1 - 2e-14 54.7 0.2 2.8e-14 54.2 0.2 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FhuF_C PF11575.8 PXF41825.1 - 0.072 13.0 0.3 0.24 11.4 0.3 2.0 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain Glyco_transf_24 PF18404.1 PXF41826.1 - 5.5e-134 445.7 0.1 8.3e-134 445.1 0.1 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 UDP-g_GGTase PF06427.11 PXF41826.1 - 1.4e-23 83.1 0.0 3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_14 PF18402.1 PXF41826.1 - 2.3e-09 37.6 0.8 4e-06 27.0 0.3 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 PXF41826.1 - 0.00044 19.9 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Thioredoxin_12 PF18400.1 PXF41826.1 - 0.0063 16.4 3.0 0.014 15.3 0.5 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Myb_DNA-binding PF00249.31 PXF41827.1 - 2.4e-15 56.5 0.6 3.7e-15 55.8 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain KHA PF11834.8 PXF41827.1 - 1.7e-11 44.0 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Myb_DNA-bind_6 PF13921.6 PXF41827.1 - 1.2e-05 25.4 0.4 2.2e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 PXF41827.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 SLIDE SCA7 PF08313.12 PXF41827.1 - 0.031 14.2 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 SCA7, zinc-binding domain DCX PF03607.17 PXF41827.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Doublecortin Ribosomal_L2_C PF03947.18 PXF41828.1 - 4.3e-52 175.6 3.0 9.1e-52 174.5 3.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PXF41828.1 - 5.3e-25 87.2 0.4 2.2e-24 85.2 0.3 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain FAD_binding_3 PF01494.19 PXF41829.1 - 2.2e-17 63.4 1.8 1.3e-16 60.8 1.8 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PXF41829.1 - 0.00022 21.4 0.0 0.00066 19.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF41829.1 - 0.0016 18.1 1.6 0.017 14.7 0.4 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PXF41829.1 - 0.0054 15.6 1.6 0.37 9.6 0.7 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 PXF41829.1 - 0.0093 16.0 0.2 1.9 8.5 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 PXF41829.1 - 0.058 12.4 0.0 0.2 10.7 0.0 1.9 2 1 0 2 2 2 0 Squalene epoxidase PS_pyruv_trans PF04230.13 PXF41829.1 - 0.088 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide pyruvyl transferase WLM PF08325.10 PXF41830.1 - 3.7e-30 105.4 1.2 5.7e-30 104.8 1.2 1.2 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 PXF41830.1 - 0.014 15.3 0.6 0.035 14.0 0.6 1.7 1 1 0 1 1 1 0 SprT-like family HSR PF03172.13 PXF41830.1 - 0.072 13.2 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 HSR domain E2F_TDP PF02319.20 PXF41831.1 - 7.4e-09 35.5 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 PXF41831.1 - 2.8e-07 30.5 1.6 7e-06 26.0 1.6 2.2 1 1 0 1 1 1 1 Transcription factor DP GcpE PF04551.14 PXF41832.1 - 9.6e-141 468.9 0.5 1.1e-140 468.7 0.5 1.0 1 0 0 1 1 1 1 GcpE protein MutS_V PF00488.21 PXF41833.1 - 1.8e-30 106.4 0.1 6.8e-30 104.5 0.1 2.0 2 1 0 2 2 2 1 MutS domain V Smr PF01713.21 PXF41833.1 - 9.3e-16 58.0 0.2 3.7e-15 56.0 0.2 2.1 1 0 0 1 1 1 1 Smr domain Baculo_PEP_C PF04513.12 PXF41833.1 - 0.052 13.6 0.8 5.9 6.9 0.1 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MutS_III PF05192.18 PXF41833.1 - 0.14 12.4 10.2 0.085 13.1 2.6 2.5 2 0 0 2 2 2 0 MutS domain III NPV_P10 PF05531.12 PXF41833.1 - 0.29 11.6 2.3 1.1 9.8 0.1 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glyco_tran_28_C PF04101.16 PXF41833.1 - 0.84 9.6 3.2 1.2 9.1 2.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DUF4456 PF14644.6 PXF41833.1 - 1.4 8.6 11.3 15 5.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) Cytochrom_B562 PF07361.11 PXF41833.1 - 1.9 9.2 7.3 6.2 7.5 4.3 3.0 3 0 0 3 3 3 0 Cytochrome b562 Filament PF00038.21 PXF41833.1 - 5.8 6.4 12.9 0.019 14.5 1.6 2.5 4 0 0 4 4 4 0 Intermediate filament protein LSM PF01423.22 PXF41834.1 - 6.5e-18 64.2 0.1 7.4e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF41834.1 - 0.014 15.5 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol3_alpha PF07733.12 PXF41835.1 - 1.8e-94 316.2 0.0 3.5e-94 315.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 PXF41835.1 - 1.9e-57 193.3 0.0 4.1e-57 192.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 PXF41835.1 - 2.3e-42 145.1 0.0 5e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 PXF41835.1 - 1.6e-25 89.1 0.1 4.7e-25 87.7 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif ABC2_membrane PF01061.24 PXF41838.1 - 7.1e-41 139.9 16.6 7.1e-41 139.9 16.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PXF41838.1 - 4e-25 88.9 0.1 7.4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PXF41838.1 - 1.8e-05 24.1 23.4 3e-05 23.3 23.4 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PXF41838.1 - 0.00013 22.4 0.0 0.00024 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF41838.1 - 0.00064 19.7 0.2 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PXF41838.1 - 0.006 16.4 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 PXF41838.1 - 0.01 15.1 0.1 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 PXF41838.1 - 0.051 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PXF41838.1 - 0.054 13.8 0.1 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PXF41838.1 - 0.1 12.7 0.6 0.2 11.7 0.6 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 PXF41838.1 - 0.17 10.7 0.0 0.66 8.7 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) RNA_helicase PF00910.22 PXF41838.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Mu-like_Com PF10122.9 PXF41839.1 - 0.0017 17.8 1.6 0.0031 16.9 1.6 1.3 1 0 0 1 1 1 1 Mu-like prophage protein Com zf-RanBP PF00641.18 PXF41839.1 - 0.0019 17.5 3.3 0.0028 16.9 3.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 PXF41839.1 - 0.01 15.8 0.7 0.018 15.0 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 PXF41839.1 - 0.065 12.7 3.1 0.11 11.9 3.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-tcix PF14952.6 PXF41839.1 - 0.25 11.0 4.5 0.4 10.3 4.5 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding FIST PF08495.10 PXF41840.1 - 1.8e-09 37.8 0.0 2e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 FIST N domain LNS2 PF08235.13 PXF41843.1 - 1.3e-90 302.9 0.0 1.6e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF4218 PF13960.6 PXF41844.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Catalase PF00199.19 PXF41846.1 - 6.2e-152 506.1 0.4 8.3e-152 505.7 0.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PXF41846.1 - 8.3e-15 54.7 0.6 1.7e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Retrotrans_gag PF03732.17 PXF41847.1 - 1.2e-12 47.9 0.0 3e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein TetR_C_32 PF09209.11 PXF41847.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M20 PF01546.28 PXF41848.1 - 1.4e-10 41.2 0.0 4.3e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 FMO-like PF00743.19 PXF41849.1 - 2.5e-43 148.3 0.0 4e-42 144.3 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PXF41849.1 - 2.2e-12 46.9 0.0 1.1e-09 38.0 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PXF41849.1 - 1.6e-10 40.7 0.1 2.2e-08 33.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 PXF41849.1 - 1.3e-09 37.8 0.0 6.1e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PXF41849.1 - 5.9e-06 26.4 0.0 2.3e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PXF41849.1 - 1.3e-05 25.3 0.0 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 PXF41849.1 - 1.4e-05 24.9 0.0 0.0017 18.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PXF41849.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PXF41849.1 - 0.16 12.4 0.0 0.84 10.1 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Ephrin_rec_like PF07699.13 PXF41850.1 - 1.7e-10 40.5 98.5 7.2e-05 22.5 2.1 11.2 3 3 10 13 13 13 9 Putative ephrin-receptor like NCD3G PF07562.14 PXF41850.1 - 5.4e-10 39.1 69.8 0.0053 16.7 1.0 9.4 6 2 3 10 10 10 9 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 PXF41850.1 - 6.1e-05 22.1 58.6 0.011 14.6 8.5 4.3 1 1 3 4 4 4 3 Giardia variant-specific surface protein Malectin PF11721.8 PXF41851.1 - 3e-15 56.7 0.0 3.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Malectin domain Malectin_like PF12819.7 PXF41851.1 - 0.00099 18.4 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Malectin-like domain Transposase_21 PF02992.14 PXF41853.1 - 2.3e-05 23.7 0.0 4.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 PXF41853.1 - 0.054 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) PPO1_DWL PF12142.8 PXF41853.1 - 0.097 12.5 0.2 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Polyphenol oxidase middle domain Ribosomal_S7e PF01251.18 PXF41854.1 - 0.08 12.7 0.7 2 8.2 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein S7e CENP-B_N PF04218.13 PXF41856.1 - 0.0003 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 PXF41856.1 - 0.0025 17.5 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 PXF41856.1 - 0.012 15.8 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 PXF41856.1 - 0.036 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_3 PF01381.22 PXF41856.1 - 0.041 14.0 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix DUF2661 PF10860.8 PXF41861.1 - 0.0062 16.6 0.5 0.024 14.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2661) AbfS_sensor PF18225.1 PXF41865.1 - 0.031 14.2 0.1 0.063 13.2 0.0 1.6 1 1 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain zf-C2H2_jaz PF12171.8 PXF41867.1 - 0.00094 19.4 4.5 0.00094 19.4 4.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PXF41867.1 - 0.0013 19.1 17.6 0.11 13.0 3.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF4876 PF16215.5 PXF41867.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4876) ROS_MUCR PF05443.11 PXF41867.1 - 0.03 14.4 0.4 0.043 13.9 0.4 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zf-met PF12874.7 PXF41867.1 - 0.081 13.3 10.3 0.98 9.9 6.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PXF41867.1 - 0.086 13.7 15.0 0.61 11.1 3.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PXF41867.1 - 0.21 11.9 6.7 0.3 11.4 6.7 1.4 1 1 0 1 1 1 0 C2H2-type zinc ribbon SAICAR_synt PF01259.18 PXF41868.1 - 4.2e-74 249.4 0.0 6.1e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 PXF41868.1 - 8.8e-36 122.7 0.1 1.2e-35 122.2 0.1 1.2 1 0 0 1 1 1 1 AIR carboxylase Glu_cyclase_2 PF05096.12 PXF41869.1 - 0.064 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Glutamine cyclotransferase PEGA PF08308.11 PXF41869.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 PEGA domain GP41 PF00517.17 PXF41870.1 - 0.082 12.8 0.8 0.25 11.2 0.3 2.0 2 0 0 2 2 2 0 Retroviral envelope protein zf-C2H2_jaz PF12171.8 PXF41872.1 - 0.00088 19.5 5.1 0.00088 19.5 5.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PXF41872.1 - 0.0054 17.1 17.8 0.27 11.8 3.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 PXF41872.1 - 0.022 15.1 3.3 0.046 14.0 3.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 PXF41872.1 - 0.23 11.9 10.3 2.2 8.8 6.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PXF41872.1 - 0.5 11.3 16.3 1.3 10.0 3.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger ELFV_dehydrog PF00208.21 PXF41873.1 - 7.6e-12 45.5 0.5 1.4e-07 31.5 0.0 2.5 2 1 1 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.24 PXF41873.1 - 2.9e-05 23.8 0.2 0.00015 21.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase ELFV_dehydrog_N PF02812.18 PXF41873.1 - 3.2e-05 23.8 0.0 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_8 PF13450.6 PXF41873.1 - 0.00025 21.2 0.1 0.00071 19.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2114 PF09887.9 PXF41873.1 - 0.0022 16.6 0.0 0.05 12.1 0.0 2.1 1 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2114) Thi4 PF01946.17 PXF41873.1 - 0.0023 17.2 0.7 0.017 14.4 0.1 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 PXF41873.1 - 0.0047 16.2 0.1 0.0083 15.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF41873.1 - 0.0073 15.4 0.6 0.011 14.8 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 PXF41873.1 - 0.0074 16.4 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 PXF41873.1 - 0.017 14.7 0.1 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 PXF41873.1 - 0.019 15.1 0.1 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain TFIID_NTD2 PF04494.15 PXF41873.1 - 0.032 14.5 0.1 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain Sacchrp_dh_NADP PF03435.18 PXF41873.1 - 0.047 13.9 0.4 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 PXF41873.1 - 0.077 12.1 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Tymo_coat PF00983.18 PXF41873.1 - 0.13 12.0 0.2 0.27 11.1 0.2 1.5 1 1 0 1 1 1 0 Tymovirus coat protein Viral_DNA_Zn_bi PF03728.13 PXF41873.1 - 0.15 12.6 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Viral DNA-binding protein, zinc binding domain 2-Hacid_dh_C PF02826.19 PXF41873.1 - 0.23 10.8 0.8 1.9 7.8 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 PXF41874.1 - 8.5e-08 32.2 0.0 9.4e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF728 PF05304.12 PXF41874.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Methyltransf_7 PF03492.15 PXF41875.1 - 1.1e-18 67.6 0.0 3.6e-16 59.3 0.0 2.1 1 1 1 2 2 2 2 SAM dependent carboxyl methyltransferase DAO PF01266.24 PXF41875.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3094 PF11293.8 PXF41877.1 - 0.074 12.8 3.9 0.091 12.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) XendoU PF09412.10 PXF41884.1 - 8.7e-34 116.9 0.4 1.1e-33 116.6 0.4 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU LTD PF00932.19 PXF41884.1 - 7.6e-05 23.0 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 Lamin Tail Domain EndoU_bacteria PF14436.6 PXF41884.1 - 0.066 13.6 0.0 0.44 10.9 0.0 2.2 1 1 1 2 2 2 0 Bacterial EndoU nuclease Pkinase PF00069.25 PXF41885.1 - 8.2e-17 61.4 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41885.1 - 2.1e-09 37.0 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF41885.1 - 0.0063 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF41885.1 - 0.014 15.3 0.2 0.34 10.8 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 PXF41885.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Kinase-like PF14531.6 PXF41885.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Methyltransf_11 PF08241.12 PXF41886.1 - 1.2e-07 32.3 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41886.1 - 4.6e-06 26.5 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41886.1 - 4.9e-06 26.5 0.0 7.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41886.1 - 0.0021 18.8 0.0 0.0041 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41886.1 - 0.014 16.1 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 PXF41886.1 - 0.13 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pyridoxal_deC PF00282.19 PXF41887.1 - 7e-17 61.2 0.0 1.8e-15 56.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 PXF41887.1 - 0.014 14.1 0.0 0.6 8.7 0.0 2.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SNF PF00209.18 PXF41888.1 - 1.3e-106 357.4 36.5 1.1e-67 228.9 13.6 3.1 1 1 1 3 3 3 3 Sodium:neurotransmitter symporter family YiaAB PF05360.14 PXF41888.1 - 0.23 11.7 0.1 0.23 11.7 0.1 5.6 6 1 1 7 7 7 0 yiaA/B two helix domain DUF2663 PF10864.8 PXF41888.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2663) Ephrin_rec_like PF07699.13 PXF41889.1 - 4e-32 109.7 78.2 1.1e-08 34.7 7.2 8.0 2 2 5 8 8 8 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 PXF41889.1 - 1.8e-08 34.6 53.3 0.025 15.0 1.4 9.8 5 4 6 11 11 11 7 TNFR/NGFR cysteine-rich region Phage_CI_repr PF07022.13 PXF41889.1 - 0.17 12.0 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain RAMP4 PF06624.12 PXF41890.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 IL2 PF00715.17 PXF41891.1 - 0.054 13.4 0.3 0.099 12.6 0.3 1.4 1 0 0 1 1 1 0 Interleukin 2 Phage_integrase PF00589.22 PXF41892.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Peptidase_S8 PF00082.22 PXF41894.1 - 3e-18 66.1 10.7 4.2e-18 65.6 10.7 1.2 1 0 0 1 1 1 1 Subtilase family Methyltransf_11 PF08241.12 PXF41895.1 - 1.4e-07 32.1 0.0 2.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF41895.1 - 5.8e-07 29.5 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41895.1 - 7.4e-06 25.8 0.0 7.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41895.1 - 0.0011 19.7 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41895.1 - 0.033 14.9 0.0 0.064 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WXG100 PF06013.12 PXF41896.1 - 0.002 18.4 0.1 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF41896.1 - 0.14 12.3 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF41896.1 - 0.56 10.9 3.8 1.1 10.0 3.8 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Adap_comp_sub PF00928.21 PXF41899.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family FAD-SLDH PF12318.8 PXF41901.1 - 0.12 12.4 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Neisseria_TspB PF05616.13 PXF41901.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein YusW PF14039.6 PXF41902.1 - 0.095 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 YusW-like protein DNA_pol3_theta PF06440.11 PXF41902.1 - 0.16 11.7 2.0 2.2 8.0 0.7 2.7 2 0 0 2 2 2 0 DNA polymerase III, theta subunit DUF4203 PF13886.6 PXF41904.1 - 4.5e-14 52.6 26.4 6.7e-14 52.0 26.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF543 PF04418.12 PXF41904.1 - 0.78 9.8 4.8 2.1 8.4 4.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Fcf2 PF08698.11 PXF41905.1 - 1.3e-26 92.8 1.6 1.9e-26 92.3 0.0 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Plant_tran PF04827.14 PXF41914.1 - 2.3e-22 79.6 0.1 2.5e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF41914.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Mtr2 PF10429.9 PXF41915.1 - 0.091 12.7 1.1 0.23 11.4 0.1 2.2 3 0 0 3 3 3 0 Nuclear pore RNA shuttling protein Mtr2 Aminotran_3 PF00202.21 PXF41920.1 - 4.4e-108 361.5 0.1 5.1e-108 361.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_8 PF06259.12 PXF41920.1 - 0.02 14.6 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Beta_elim_lyase PF01212.21 PXF41920.1 - 0.054 12.8 0.0 0.26 10.5 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase PolyA_pol PF01743.20 PXF41921.1 - 1.7e-26 93.1 0.2 2.7e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 PXF41921.1 - 3.5e-05 23.5 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF3464 PF11947.8 PXF41923.1 - 6.5e-29 100.6 5.0 3.3e-28 98.3 5.0 1.8 1 1 0 1 1 1 1 Photosynthesis affected mutant 68 DUF2339 PF10101.9 PXF41923.1 - 0.094 11.3 3.2 0.13 10.9 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) zf-RING_2 PF13639.6 PXF41924.1 - 3.2e-07 30.6 4.6 3.2e-07 30.6 4.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 PXF41924.1 - 0.00032 20.9 4.5 0.00032 20.9 4.5 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF41924.1 - 0.00051 20.1 2.3 0.0032 17.5 2.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 PXF41924.1 - 0.00059 20.1 4.0 0.00059 20.1 4.0 2.5 3 0 0 3 3 3 1 RING-like domain SWIM PF04434.17 PXF41924.1 - 0.0012 18.5 0.1 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 PXF41924.1 - 0.0043 16.9 5.3 0.01 15.7 5.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.25 PXF41924.1 - 0.0067 16.3 5.7 0.0067 16.3 5.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF41924.1 - 0.0083 16.1 6.2 0.0083 16.1 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_1 PF14446.6 PXF41924.1 - 0.018 14.9 6.5 0.052 13.5 1.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 PXF41924.1 - 0.064 13.2 5.4 0.14 12.2 4.4 2.1 1 1 0 1 1 1 0 zinc-ribbons DUF3659 PF12396.8 PXF41924.1 - 0.082 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Zf_RING PF16744.5 PXF41924.1 - 0.091 12.9 2.0 0.21 11.7 2.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 PXF41924.1 - 0.11 12.6 7.1 0.096 12.8 3.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 PXF41924.1 - 0.12 12.4 7.4 0.37 10.8 6.2 2.4 2 1 1 3 3 3 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 PXF41924.1 - 0.19 11.6 11.4 0.077 12.9 7.0 2.7 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 PXF41924.1 - 0.22 11.5 5.5 1 9.3 1.7 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 PXF41924.1 - 0.37 10.6 11.7 0.038 13.8 6.1 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PXF41924.1 - 0.66 9.9 13.0 0.063 13.2 7.0 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PXF41924.1 - 0.69 10.1 11.1 0.25 11.5 6.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 PXF41924.1 - 4.8 7.3 11.1 0.094 12.8 3.5 2.2 2 0 0 2 2 2 0 RING-type zinc-finger PCI PF01399.27 PXF41925.1 - 2.3e-12 47.3 0.0 6.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 PXF41925.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Trehalose_PPase PF02358.16 PXF41926.1 - 4.7e-08 32.4 0.0 5.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase RuvC PF02075.17 PXF41927.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC EST1_DNA_bind PF10373.9 PXF41927.1 - 0.082 12.4 0.2 0.36 10.3 0.1 1.9 1 1 1 2 2 2 0 Est1 DNA/RNA binding domain MRNIP PF15749.5 PXF41929.1 - 2.6e-18 66.7 0.2 5.4e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 MRN-interacting protein Ima1_N PF09779.9 PXF41929.1 - 0.093 13.6 1.9 0.093 13.6 1.9 1.9 2 0 0 2 2 2 0 Ima1 N-terminal domain Ribosomal_S27e PF01667.17 PXF41929.1 - 0.29 10.9 4.1 0.5 10.1 4.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 HLH PF00010.26 PXF41930.1 - 0.00021 21.2 0.1 0.00045 20.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAF_2 PF13185.6 PXF41930.1 - 0.00033 21.0 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PXF41930.1 - 0.022 15.4 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain Diphthami_syn_2 PF01902.17 PXF41931.1 - 1.6e-38 132.5 0.0 2.6e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 PXF41931.1 - 2e-18 66.6 0.0 1.4e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 PXF41931.1 - 0.072 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asparaginase_C PF17763.1 PXF41931.1 - 0.13 12.5 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain NusB PF01029.18 PXF41931.1 - 0.16 12.2 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 NusB family TACC_C PF05010.14 PXF41932.1 - 3.4e-10 40.0 27.6 3.4e-10 40.0 27.6 4.0 2 1 2 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HR1 PF02185.16 PXF41932.1 - 0.014 15.5 6.9 0.014 15.5 6.9 4.4 4 0 0 4 4 4 0 Hr1 repeat PI3K_P85_iSH2 PF16454.5 PXF41932.1 - 0.045 13.4 40.8 0.19 11.3 18.8 3.8 1 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PKcGMP_CC PF16808.5 PXF41932.1 - 0.061 13.2 23.6 0.079 12.8 3.4 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 PXF41932.1 - 1.7 6.0 40.6 4.9 4.5 40.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 PXF41932.1 - 2 7.8 38.5 0.81 9.1 14.4 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) HMMR_N PF15905.5 PXF41932.1 - 3.2 7.2 56.0 0.054 13.0 9.1 4.1 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal AAT PF03417.16 PXF41932.1 - 4.8 6.8 9.2 1 9.0 0.4 3.3 3 1 1 4 4 4 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Endonuclease_5 PF04493.14 PXF41933.1 - 2.6e-45 154.5 0.0 3.4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V dsrm PF00035.26 PXF41934.1 - 2.9e-07 31.1 0.3 0.021 15.5 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 PXF41934.1 - 0.00063 19.8 0.2 1.8 8.7 0.0 2.6 2 0 0 2 2 2 2 Dicer dimerisation domain DND1_DSRM PF14709.7 PXF41934.1 - 0.016 15.4 0.1 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ras PF00071.22 PXF41935.1 - 8e-59 197.9 0.1 1e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF41935.1 - 2.2e-36 124.7 0.1 3.2e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF41935.1 - 4.1e-15 55.7 0.1 5e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PXF41935.1 - 4.5e-06 26.3 0.1 1.7e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PXF41935.1 - 7.4e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PXF41935.1 - 9.7e-05 21.8 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF41935.1 - 0.00091 19.3 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PXF41935.1 - 0.0018 18.5 0.0 0.095 13.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PXF41935.1 - 0.0018 18.2 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 PXF41935.1 - 0.0053 16.3 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 PXF41935.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 PXF41935.1 - 0.01 16.2 0.0 0.034 14.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 PXF41935.1 - 0.034 13.5 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 PXF41935.1 - 0.048 13.4 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain UPF0449 PF15136.6 PXF41935.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 PduV-EutP PF10662.9 PXF41935.1 - 0.12 12.2 0.3 0.24 11.1 0.3 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1863 PF08937.11 PXF41935.1 - 0.13 12.6 0.2 0.78 10.1 0.1 2.0 1 1 1 2 2 2 0 MTH538 TIR-like domain (DUF1863) Ribosomal_L17 PF01196.19 PXF41936.1 - 1.1e-34 119.1 0.1 2e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Herpes_US9 PF06072.11 PXF41936.1 - 0.15 11.9 4.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 ASF1_hist_chap PF04729.13 PXF41937.1 - 1.6e-58 197.0 0.0 1.8e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone FA_hydroxylase PF04116.13 PXF41938.1 - 7.2e-28 97.6 19.1 7.2e-28 97.6 19.1 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily SRP40_C PF05022.12 PXF41939.1 - 2e-21 76.6 5.0 2e-21 76.6 5.0 2.7 2 0 0 2 2 2 1 SRP40, C-terminal domain SIP PF04954.13 PXF41941.1 - 0.051 14.1 0.6 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Siderophore-interacting protein RRM_1 PF00076.22 PXF41942.1 - 2e-40 136.5 0.0 2e-18 65.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF41942.1 - 0.00024 20.7 0.0 0.23 11.0 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF41942.1 - 0.00028 20.9 0.1 0.0098 16.0 0.0 3.0 2 2 1 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 PXF41942.1 - 0.093 12.8 0.1 23 5.1 0.0 2.8 2 1 1 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 PXF41942.1 - 0.1 12.9 0.2 4.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Lon_C PF05362.13 PXF41943.1 - 3.6e-69 232.4 0.0 6.8e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 PXF41943.1 - 5e-19 69.0 0.0 1.4e-18 67.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF41943.1 - 1.5e-06 28.7 0.1 7e-05 23.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PXF41943.1 - 1.8e-06 28.0 0.0 4.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF41943.1 - 1.4e-05 25.4 0.3 0.0025 18.1 0.0 3.8 1 1 2 3 3 3 1 AAA domain AAA_PrkA PF08298.11 PXF41943.1 - 1.5e-05 24.1 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 PXF41943.1 - 3.8e-05 23.5 0.0 0.00015 21.5 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 PXF41943.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 PXF41943.1 - 0.00032 20.5 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 PXF41943.1 - 0.00037 20.6 0.1 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PXF41943.1 - 0.00054 19.3 0.4 0.0075 15.5 0.1 2.3 1 1 1 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 PXF41943.1 - 0.0022 18.3 0.0 0.0057 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 PXF41943.1 - 0.0034 17.3 2.7 0.25 11.3 0.0 2.6 2 1 1 3 3 3 1 NTPase AAA_18 PF13238.6 PXF41943.1 - 0.0044 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 PXF41943.1 - 0.0067 16.6 0.5 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_30 PF13604.6 PXF41943.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 PXF41943.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 PXF41943.1 - 0.018 15.1 0.0 0.099 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PXF41943.1 - 0.056 13.8 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PXF41943.1 - 0.098 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 PXF41943.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ParA PF10609.9 PXF41943.1 - 0.11 12.0 0.2 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 PXF41943.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 PXF41943.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 PXF41943.1 - 0.3 10.2 1.8 0.45 9.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain LON_substr_bdg PF02190.16 PXF41944.1 - 5.6e-16 59.0 0.0 7.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Herpes_BLLF1 PF05109.13 PXF41944.1 - 1.6 6.6 5.5 2.1 6.2 5.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Thioredoxin PF00085.20 PXF41946.1 - 3.5e-17 62.3 0.0 4.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 PXF41947.1 - 7.6e-13 48.3 0.0 2.7e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 PXF41947.1 - 3.4e-09 36.9 0.1 1.1e-05 25.4 0.0 2.5 2 1 0 2 2 2 2 Thioredoxin-like domain ERp29_N PF07912.13 PXF41947.1 - 0.002 18.2 0.1 0.007 16.5 0.0 2.0 2 0 0 2 2 2 1 ERp29, N-terminal domain KASH PF10541.9 PXF41948.1 - 0.019 15.2 0.2 0.019 15.2 0.2 2.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain Trehalose_PPase PF02358.16 PXF41949.1 - 1.3e-07 31.0 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase RETICULATA-like PF11891.8 PXF41950.1 - 7.6e-27 94.3 0.0 4.7e-25 88.4 0.0 2.2 1 1 0 1 1 1 1 Protein RETICULATA-related ATP_transf PF09830.9 PXF41950.1 - 0.032 14.4 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 ATP adenylyltransferase DUF1635 PF07795.11 PXF41951.1 - 0.0068 16.3 1.4 0.026 14.4 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Trp_oprn_chp PF09534.10 PXF41951.1 - 0.028 14.2 0.7 0.028 14.2 0.7 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YebO PF13974.6 PXF41951.1 - 0.3 11.2 3.3 1.4 9.1 0.4 2.5 2 0 0 2 2 2 0 YebO-like protein PH PF00169.29 PXF41952.1 - 1e-07 32.4 1.0 2.2e-07 31.3 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 PXF41952.1 - 0.0015 18.9 0.7 0.43 11.0 0.1 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_13 PF16652.5 PXF41952.1 - 0.079 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Lzipper-MIP1 PF14389.6 PXF41952.1 - 0.11 12.9 0.7 2.6 8.4 0.0 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 PH_11 PF15413.6 PXF41952.1 - 0.12 12.8 1.3 0.39 11.2 1.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Dus PF01207.17 PXF41954.1 - 5.7e-53 180.0 0.0 7.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 PXF41954.1 - 0.11 11.7 0.0 0.45 9.7 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase DUF758 PF05527.11 PXF41955.1 - 0.047 13.7 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Glyco_transf_11 PF01531.16 PXF41959.1 - 3.9e-25 88.7 0.2 1.3e-24 86.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 11 Peptidase_M76 PF09768.9 PXF41959.1 - 0.0076 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family Acyl_transf_3 PF01757.22 PXF41960.1 - 4.4e-31 108.2 31.5 4.4e-31 108.2 31.5 1.7 2 0 0 2 2 2 1 Acyltransferase family DUF2614 PF11023.8 PXF41960.1 - 9 6.4 6.6 1.3 9.1 0.7 2.6 2 1 1 3 3 3 0 Zinc-ribbon containing domain Glyco_transf_4 PF13439.6 PXF41961.1 - 1.1e-05 25.5 0.1 1.9e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PXF41961.1 - 0.014 15.8 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 PXF41962.1 - 5.2e-21 74.9 0.0 2e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF41962.1 - 3.6e-15 56.6 0.0 6.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF41962.1 - 0.0044 17.0 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 PXF41962.1 - 0.13 12.7 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Nucleotid_trans PF03407.16 PXF41964.1 - 5.1e-27 95.2 0.0 7.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Methyltransf_21 PF05050.12 PXF41965.1 - 0.0023 18.0 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3452 PF11934.8 PXF41968.1 - 0.0071 15.9 0.7 0.02 14.4 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) RB_B PF01857.20 PXF41969.1 - 7.7e-26 90.7 0.5 1.3e-25 90.0 0.5 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 PXF41969.1 - 2.1e-22 80.0 0.3 3.2e-22 79.3 0.3 1.2 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain KIX_2 PF16987.5 PXF41970.1 - 1.5e-22 79.4 1.4 0.00023 21.1 0.3 6.1 5 1 0 5 5 5 5 KIX domain KIX PF02172.16 PXF41970.1 - 7.3e-06 26.2 4.5 0.19 12.0 0.5 5.9 6 2 0 6 6 6 2 KIX domain DUF4600 PF15372.6 PXF41970.1 - 0.17 12.3 1.2 0.5 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4718 PF15842.5 PXF41971.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Ribosomal_S2 PF00318.20 PXF41972.1 - 6.7e-31 107.2 0.2 1e-15 57.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 PXF41972.1 - 0.00032 22.0 19.3 0.011 17.0 19.3 2.7 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus TPR_12 PF13424.6 PXF41973.1 - 0.0034 17.6 0.5 0.0034 17.6 0.5 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF5548 PF17702.1 PXF41973.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5548) TPR_1 PF00515.28 PXF41973.1 - 0.099 12.5 3.7 17 5.4 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF41974.1 - 2.9e-29 98.8 1.8 2.4e-05 24.2 0.1 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 PXF41974.1 - 2e-27 93.8 9.3 7.3e-08 31.9 0.3 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 PXF41974.1 - 6e-23 79.1 19.1 1.5e-06 27.8 0.9 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 PXF41974.1 - 5.3e-18 64.2 22.3 0.0054 17.4 0.9 10.8 5 4 5 10 10 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF41974.1 - 3.5e-17 62.4 24.1 9.1e-15 54.7 2.1 5.5 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF41974.1 - 6.2e-15 54.0 16.4 4.1e-05 23.3 0.4 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF41974.1 - 4.8e-14 52.4 33.0 5.7e-08 32.9 3.3 8.5 4 3 2 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF41974.1 - 1.1e-13 50.5 0.3 0.1 12.3 0.0 6.4 6 1 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 PXF41974.1 - 3.1e-12 46.9 20.9 0.001 19.6 0.5 6.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 PXF41974.1 - 9.3e-12 44.8 12.3 0.033 14.8 0.1 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 PXF41974.1 - 2.3e-10 40.2 7.4 0.00045 19.5 0.3 5.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF41974.1 - 6.4e-09 36.2 16.7 0.054 14.0 1.8 5.7 4 2 1 5 5 5 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PXF41974.1 - 6.3e-05 23.0 0.5 0.00033 20.7 0.0 2.2 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_10 PF13374.6 PXF41974.1 - 7.5e-05 22.5 29.0 0.064 13.2 0.1 7.7 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 PXF41974.1 - 7.9e-05 22.7 23.3 0.02 15.0 1.9 5.7 5 3 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF41974.1 - 0.00018 21.7 12.9 10 6.8 0.1 7.6 8 1 0 8 8 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PXF41974.1 - 0.015 14.9 0.9 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Rotavirus_VP3 PF06929.11 PXF41974.1 - 0.049 11.8 0.0 0.086 11.1 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP3 protein ANAPC8 PF04049.13 PXF41974.1 - 0.25 11.4 0.8 6.4 6.8 0.1 2.8 2 1 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 Fis1_TPR_C PF14853.6 PXF41974.1 - 0.33 11.1 9.0 2.6 8.2 0.3 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 PXF41974.1 - 2.2 9.2 19.1 2.3 9.1 0.3 7.7 7 1 1 8 8 7 0 Tetratricopeptide repeat Pkinase PF00069.25 PXF41975.1 - 6e-22 78.3 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF41975.1 - 2.8e-08 33.4 0.0 5.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF41975.1 - 2.9e-07 29.6 0.0 4.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PXF41975.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 PXF41975.1 - 0.03 14.2 0.1 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 PXF41976.1 - 2.4e-13 50.2 0.0 3.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF41976.1 - 2.6e-11 44.2 0.0 4.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF41976.1 - 2.9e-09 37.5 0.0 5.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF41976.1 - 1e-06 29.3 0.0 2.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF41976.1 - 2.3e-05 24.2 0.0 6.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF41976.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MIF4G_like PF09088.11 PXF41977.1 - 1.2e-28 100.1 0.2 1e-26 93.9 0.0 2.3 1 1 1 2 2 2 2 MIF4G like MIF4G_like_2 PF09090.11 PXF41977.1 - 1.8e-20 73.5 0.0 3.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 PXF41977.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain TPT PF03151.16 PXF41978.1 - 7e-26 91.2 22.7 8.2e-26 91.0 22.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF41978.1 - 2.8e-09 37.3 30.4 7.2e-05 23.0 12.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Tail_VII PF17091.5 PXF41978.1 - 0.14 12.1 4.7 0.81 9.6 0.2 2.8 2 0 0 2 2 2 0 Inovirus G7P protein Sh_2 PF17512.2 PXF41978.1 - 0.3 10.8 0.1 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein CoA_binding_3 PF13727.6 PXF41978.1 - 5.6 6.9 9.5 0.081 12.9 0.8 2.4 2 1 0 2 2 2 0 CoA-binding domain DUF2207 PF09972.9 PXF41978.1 - 5.9 5.5 7.3 28 3.3 0.0 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) HECT PF00632.25 PXF41979.1 - 2.3e-78 263.8 0.4 3.1e-78 263.3 0.4 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PXF41979.1 - 7.5e-54 180.2 11.3 2.2e-10 41.0 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF41979.1 - 9.7e-34 114.5 36.8 1.2e-07 31.4 0.9 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat HAD_2 PF13419.6 PXF41980.1 - 3.6e-08 33.7 0.0 7.6e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF41980.1 - 9.4e-06 26.0 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF41980.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like LpxC PF03331.13 PXF41981.1 - 1.6e-65 221.3 0.0 1.8e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase RNase_H PF00075.24 PXF41982.1 - 1.8e-15 57.4 0.4 7e-08 32.8 0.1 2.3 2 0 0 2 2 2 2 RNase H Amino_oxidase PF01593.24 PXF41982.1 - 3.3e-12 46.4 0.2 7.7e-12 45.2 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF41982.1 - 1.6e-10 41.1 0.1 4.5e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PXF41982.1 - 9.3e-06 25.0 0.6 0.068 12.2 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain zf-C2H2 PF00096.26 PXF41982.1 - 0.0003 21.1 0.8 1.8 9.1 0.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF41982.1 - 0.00037 21.1 8.7 0.046 14.6 0.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 PXF41982.1 - 0.0016 18.2 0.2 1.1 9.1 0.0 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 PXF41982.1 - 0.004 17.5 0.3 0.004 17.5 0.3 2.0 2 0 0 2 2 1 1 C2H2 type zinc-finger (2 copies) HI0933_like PF03486.14 PXF41982.1 - 0.0058 15.4 0.0 0.22 10.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 PXF41982.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family zf_C2H2_ZHX PF18387.1 PXF41982.1 - 0.024 14.2 0.1 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain FAD_binding_3 PF01494.19 PXF41982.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain zf-C2H2_jaz PF12171.8 PXF41982.1 - 0.93 9.9 3.8 3.2 8.2 0.0 3.0 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding 2OG-FeII_Oxy_3 PF13640.6 PXF41984.1 - 0.00023 22.0 0.0 0.0005 20.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FKBP_C PF00254.28 PXF41985.1 - 2.6e-18 66.1 0.0 3.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Piwi PF02171.17 PXF41985.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Piwi domain Band_7 PF01145.25 PXF41986.1 - 1.8e-24 86.8 1.0 2.7e-24 86.1 1.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 PXF41986.1 - 0.022 14.9 1.6 0.037 14.2 1.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF1098 PF06497.11 PXF41986.1 - 0.082 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) SRRM_C PF15230.6 PXF41986.1 - 0.13 12.8 0.1 0.36 11.4 0.1 1.7 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus Sigma70_r2 PF04542.14 PXF41988.1 - 1.2e-21 76.3 0.0 3.2e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PXF41988.1 - 2.2e-20 71.9 1.4 7.4e-20 70.2 0.7 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 PXF41988.1 - 1.3e-14 54.0 1.1 2.6e-10 40.3 0.2 3.4 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 PXF41988.1 - 4.9e-09 36.0 0.2 1.5e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 PXF41988.1 - 3.6e-05 23.4 1.4 0.0074 15.9 0.1 3.5 3 1 0 3 3 3 1 Sigma-70, region 4 DKCLD PF08068.12 PXF41988.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 DKCLD (NUC011) domain HNH_repeat PF18780.1 PXF41988.1 - 0.12 12.1 0.2 0.34 10.8 0.2 1.8 1 0 0 1 1 1 0 Homing endonuclease repeat Fasciclin PF02469.22 PXF41989.1 - 1.3e-14 54.5 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain zf-4CXXC_R1 PF10497.9 PXF41990.1 - 0.0066 16.6 12.9 0.013 15.7 12.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-SNAP50_C PF12251.8 PXF41990.1 - 0.24 11.1 2.2 0.37 10.4 2.2 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zinc_ribbon_10 PF10058.9 PXF41990.1 - 1.7 8.4 5.7 1.7 8.4 3.8 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Polyketide_cyc2 PF10604.9 PXF41991.1 - 1.3e-07 32.0 0.1 1.9e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PXF41991.1 - 2.8e-07 30.8 0.1 3.9e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribosomal_L31e PF01198.19 PXF41992.1 - 1.5e-40 137.3 1.2 1.7e-40 137.1 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 PXF41992.1 - 0.19 11.8 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF3552 PF12072.8 PXF41993.1 - 0.0057 16.1 70.2 0.11 11.9 21.5 6.1 2 2 3 5 5 5 3 Domain of unknown function (DUF3552) TMF_TATA_bd PF12325.8 PXF41993.1 - 0.011 15.9 9.8 0.011 15.9 9.8 5.0 3 2 2 5 5 5 0 TATA element modulatory factor 1 TATA binding SLATT_5 PF18160.1 PXF41993.1 - 0.58 9.5 3.8 0.83 8.9 2.7 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Ly49 PF08391.10 PXF41993.1 - 1.7 9.0 16.0 0.46 10.9 0.1 3.7 3 1 0 3 3 3 0 Ly49-like protein, N-terminal region DUF4200 PF13863.6 PXF41993.1 - 4.3 7.8 59.8 1.8 9.0 17.1 5.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 PXF41993.1 - 5.8 7.5 22.0 3.3 8.2 1.2 4.8 2 2 3 5 5 5 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 PXF41993.1 - 6.6 7.1 16.5 0.44 10.9 2.1 4.3 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.27 PXF41995.1 - 3.2e-32 111.9 0.0 5.4e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PXF41995.1 - 1.2e-23 84.1 13.4 1.7e-23 83.7 13.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 PXF41995.1 - 3.8e-05 24.1 0.2 8.2e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF41995.1 - 8.6e-05 22.5 0.0 0.00025 21.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 PXF41995.1 - 0.0059 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF41995.1 - 0.01 16.1 0.0 0.03 14.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PXF41995.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 PXF41995.1 - 0.012 15.5 0.1 0.026 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PXF41995.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PXF41995.1 - 0.014 15.9 0.1 0.3 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PXF41995.1 - 0.019 15.1 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 PXF41995.1 - 0.03 14.3 0.2 0.34 10.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PXF41995.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PXF41995.1 - 0.097 12.4 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_S7 PF00177.21 PXF41996.1 - 1.3e-38 131.9 0.1 1.6e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DNA_pol_P_Exo PF18049.1 PXF41997.1 - 0.047 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo CAP PF00188.26 PXF41998.1 - 0.072 13.9 0.0 0.32 11.8 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Ephrin_rec_like PF07699.13 PXF41999.1 - 2e-05 24.3 32.6 0.0068 16.1 0.9 5.1 3 3 2 5 5 5 4 Putative ephrin-receptor like NCD3G PF07562.14 PXF41999.1 - 8e-05 22.5 18.7 0.15 12.1 0.8 3.6 3 1 0 3 3 3 3 Nine Cysteines Domain of family 3 GPCR TMEM190 PF15431.6 PXF42000.1 - 0.014 15.5 0.3 0.23 11.6 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 190 Peptidase_C48 PF02902.19 PXF42000.1 - 0.064 13.1 2.0 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain DDE_1 PF03184.19 PXF42002.1 - 4e-21 75.4 0.1 9.7e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF42002.1 - 1.1e-05 25.4 0.1 2.1e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MHC_II_alpha PF00993.20 PXF42002.1 - 0.14 11.8 0.3 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain ATP-sulfurylase PF01747.17 PXF42003.1 - 3.7e-61 206.3 0.0 4.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PXF42003.1 - 2.6e-44 150.7 0.0 5.2e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain CASP_C PF08172.12 PXF42004.1 - 3.7e-55 187.0 5.1 3.7e-55 187.0 5.1 4.1 2 1 2 4 4 2 1 CASP C terminal PKcGMP_CC PF16808.5 PXF42004.1 - 0.016 15.0 18.6 0.15 11.9 0.9 6.1 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2205 PF10224.9 PXF42004.1 - 0.025 14.6 0.2 0.025 14.6 0.2 4.9 5 1 1 6 6 5 0 Short coiled-coil protein DUF2730 PF10805.8 PXF42004.1 - 0.029 14.5 0.7 0.029 14.5 0.7 5.6 3 1 3 6 6 6 0 Protein of unknown function (DUF2730) PIP49_N PF14875.6 PXF42004.1 - 0.18 11.6 0.2 0.43 10.4 0.2 1.5 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 Filament PF00038.21 PXF42004.1 - 0.21 11.1 54.4 0.22 11.1 1.2 5.5 1 1 3 5 5 5 0 Intermediate filament protein NPV_P10 PF05531.12 PXF42004.1 - 0.26 11.8 16.9 2.8 8.5 0.1 5.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein HsbA PF12296.8 PXF42004.1 - 0.48 10.9 7.1 2.7 8.5 2.1 3.7 2 2 0 2 2 2 0 Hydrophobic surface binding protein A Pox_A_type_inc PF04508.12 PXF42004.1 - 0.48 10.4 6.1 3.7 7.6 0.1 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 PXF42004.1 - 0.48 9.2 60.8 1.3 7.9 12.1 6.2 2 1 4 6 6 6 0 Spc7 kinetochore protein STN1_2 PF09170.10 PXF42004.1 - 0.66 10.2 12.8 0.072 13.3 2.5 2.9 2 1 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF1664 PF07889.12 PXF42004.1 - 1.2 9.2 32.7 0.13 12.2 2.0 5.7 4 1 1 6 6 6 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 PXF42004.1 - 5.8 6.9 57.7 0.088 12.8 15.7 5.3 3 1 2 5 5 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 PXF42004.1 - 7.2 7.0 37.0 2.7 8.3 2.0 6.6 2 1 5 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XkdW PF09636.10 PXF42004.1 - 9 6.4 10.9 26 5.0 0.0 4.3 3 1 0 4 4 4 0 XkdW protein AAA PF00004.29 PXF42005.1 - 5.1e-43 146.7 0.0 1e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF42005.1 - 4e-12 45.7 0.0 9.5e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PXF42005.1 - 3.5e-09 36.5 1.1 7e-09 35.5 1.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PXF42005.1 - 1.4e-07 31.7 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PXF42005.1 - 4.4e-07 30.4 0.1 2.6e-05 24.6 0.1 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PXF42005.1 - 2.4e-06 27.6 0.0 8.7e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF42005.1 - 7.7e-05 23.0 0.2 0.0087 16.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PXF42005.1 - 9.4e-05 22.2 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATG16 PF08614.11 PXF42005.1 - 0.0011 19.3 5.5 0.0022 18.3 5.5 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_33 PF13671.6 PXF42005.1 - 0.0013 19.0 1.1 0.002 18.3 0.0 1.8 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 PXF42005.1 - 0.0015 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PXF42005.1 - 0.002 17.9 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PXF42005.1 - 0.0046 16.4 0.2 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 PXF42005.1 - 0.0053 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 KaiC DivIC PF04977.15 PXF42005.1 - 0.0072 16.1 4.1 0.017 14.9 4.1 1.6 1 0 0 1 1 1 1 Septum formation initiator RNA_helicase PF00910.22 PXF42005.1 - 0.0081 16.5 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 RNA helicase AAA_13 PF13166.6 PXF42005.1 - 0.0091 14.7 0.5 0.39 9.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF42005.1 - 0.01 16.4 2.0 0.014 15.9 0.0 2.2 3 1 0 3 3 1 0 AAA domain AAA_28 PF13521.6 PXF42005.1 - 0.011 16.0 0.8 0.02 15.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain TMF_TATA_bd PF12325.8 PXF42005.1 - 0.013 15.7 0.5 0.039 14.2 0.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Snapin_Pallidin PF14712.6 PXF42005.1 - 0.014 15.8 0.3 0.054 13.9 0.3 2.0 1 0 0 1 1 1 0 Snapin/Pallidin AAA_3 PF07726.11 PXF42005.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PXF42005.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MscS_porin PF12795.7 PXF42005.1 - 0.016 14.8 5.4 0.03 13.9 5.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain PhoH PF02562.16 PXF42005.1 - 0.018 14.5 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 PXF42005.1 - 0.018 14.8 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PXF42005.1 - 0.02 14.7 0.3 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 PXF42005.1 - 0.02 15.4 3.0 0.052 14.1 3.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_14 PF13173.6 PXF42005.1 - 0.026 14.5 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PXF42005.1 - 0.027 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain OmpH PF03938.14 PXF42005.1 - 0.027 14.8 1.5 0.043 14.1 0.4 1.9 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) AAA_7 PF12775.7 PXF42005.1 - 0.027 14.0 0.0 0.078 12.5 0.0 1.7 1 1 1 2 2 2 0 P-loop containing dynein motor region Spc7 PF08317.11 PXF42005.1 - 0.03 13.2 0.7 0.068 12.0 0.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 PXF42005.1 - 0.032 14.1 0.3 0.074 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_25 PF13481.6 PXF42005.1 - 0.037 13.6 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF4618 PF15397.6 PXF42005.1 - 0.038 13.4 1.5 0.085 12.3 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) AAA_19 PF13245.6 PXF42005.1 - 0.041 14.2 0.1 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain KLRAQ PF10205.9 PXF42005.1 - 0.042 14.1 0.7 0.042 14.1 0.7 1.7 2 0 0 2 2 1 0 Predicted coiled-coil domain-containing protein DUF815 PF05673.13 PXF42005.1 - 0.047 12.8 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 PXF42005.1 - 0.052 12.6 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 PXF42005.1 - 0.054 13.8 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Prominin PF05478.11 PXF42005.1 - 0.056 11.4 0.2 0.084 10.8 0.2 1.2 1 0 0 1 1 1 0 Prominin Osmo_CC PF08946.10 PXF42005.1 - 0.085 13.1 4.4 8.2 6.8 0.0 3.1 2 1 1 3 3 2 0 Osmosensory transporter coiled coil AAA_17 PF13207.6 PXF42005.1 - 0.11 13.0 0.6 0.36 11.3 0.0 2.2 3 0 0 3 3 1 0 AAA domain V_ATPase_I PF01496.19 PXF42005.1 - 0.16 9.9 0.1 0.22 9.4 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 PXF42005.1 - 0.17 12.5 2.4 0.53 10.9 2.4 1.8 1 0 0 1 1 1 0 SlyX UPF0242 PF06785.11 PXF42005.1 - 0.24 11.5 6.2 0.42 10.7 6.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 PXF42005.1 - 0.35 11.0 11.1 0.22 11.7 7.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Cep57_CLD_2 PF14197.6 PXF42005.1 - 0.46 10.6 8.1 0.32 11.1 5.1 2.3 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 Sec2p PF06428.11 PXF42005.1 - 0.79 9.7 5.5 1.6 8.8 4.6 1.9 2 0 0 2 2 1 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 PXF42005.1 - 1.6 9.2 5.3 1.7 9.1 3.5 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DUF4061 PF13270.6 PXF42005.1 - 2.3 8.6 5.1 1.8 8.9 0.3 2.9 4 0 0 4 4 2 0 Domain of unknown function (DUF4061) GHMP_kinases_C PF08544.13 PXF42005.1 - 7.2 7.1 8.7 14 6.2 0.0 4.0 4 1 1 5 5 3 0 GHMP kinases C terminal Acetyltransf_1 PF00583.25 PXF42006.1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF42006.1 - 1.9e-08 34.3 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF42006.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF42006.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PXF42006.1 - 0.0038 17.3 0.1 0.0079 16.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0113_N PF17833.1 PXF42008.1 - 3.5e-32 110.8 0.1 5.3e-32 110.2 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 PXF42008.1 - 1.4e-24 86.2 0.0 2.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 PXF42008.1 - 0.055 13.4 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 PUA domain Prefoldin PF02996.17 PXF42009.1 - 1.9e-12 47.2 0.5 3.9e-12 46.1 0.1 1.7 1 1 1 2 2 2 1 Prefoldin subunit YbaB_DNA_bd PF02575.16 PXF42010.1 - 1e-15 57.7 6.8 1.3e-15 57.4 6.8 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Flu_NP PF00506.18 PXF42010.1 - 0.031 12.9 0.7 0.037 12.7 0.7 1.0 1 0 0 1 1 1 0 Influenza virus nucleoprotein Flg_hook PF02120.16 PXF42010.1 - 0.056 13.3 0.3 1.5 8.8 0.1 2.2 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK HTH_13 PF11972.8 PXF42011.1 - 0.45 10.6 3.3 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 HTH DNA binding domain DUF5600 PF18150.1 PXF42012.1 - 1.1e-34 119.2 0.2 2.4e-34 118.1 0.1 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 PXF42012.1 - 2.3e-15 56.4 0.0 6e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 PXF42012.1 - 1.7e-14 53.4 0.3 3e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein FYVE PF01363.21 PXF42012.1 - 9.7e-13 48.1 9.9 1.5e-12 47.5 9.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger Dynamin_N PF00350.23 PXF42012.1 - 2.5e-12 47.2 0.0 5.6e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PXF42012.1 - 4.4e-09 36.4 0.0 1.3e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 PXF42012.1 - 0.00014 21.1 0.1 0.00043 19.6 0.1 1.9 1 0 0 1 1 1 1 EF hand FYVE_2 PF02318.16 PXF42012.1 - 0.0027 17.9 4.7 0.0054 16.9 4.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Roc PF08477.13 PXF42012.1 - 0.025 14.8 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 PXF42012.1 - 0.038 14.5 0.0 0.56 10.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 PXF42012.1 - 0.076 13.0 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 PXF42012.1 - 0.078 12.5 0.0 0.25 10.9 0.0 1.9 1 0 0 1 1 1 0 EF hand Ras PF00071.22 PXF42012.1 - 0.082 12.5 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Ras family IBR PF01485.21 PXF42012.1 - 0.23 11.7 7.3 0.41 10.9 7.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1963 PF09234.10 PXF42013.1 - 0.0041 17.6 0.1 0.025 15.0 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) Endonuclea_NS_2 PF13930.6 PXF42015.1 - 0.00012 22.2 0.6 0.00028 21.0 0.0 1.7 1 1 0 2 2 2 1 DNA/RNA non-specific endonuclease DUF4827 PF16109.5 PXF42015.1 - 0.06 13.3 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) Herpes_IE68 PF02479.16 PXF42015.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus immediate early protein ZZ PF00569.17 PXF42017.1 - 7.7e-11 41.6 7.2 7.7e-11 41.6 7.2 3.5 4 0 0 4 4 4 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 PXF42018.1 - 3.7e-09 35.5 0.1 3.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 EF hand Glyoxalase PF00903.25 PXF42018.1 - 1.1e-08 35.3 0.3 6.6e-08 32.8 0.0 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_6 PF13405.6 PXF42018.1 - 3.8e-06 26.4 0.2 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PXF42018.1 - 6.3e-06 26.0 0.2 0.00019 21.2 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PXF42018.1 - 2.6e-05 24.6 0.1 0.016 15.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Glyoxalase_4 PF13669.6 PXF42018.1 - 0.0052 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_5 PF13202.6 PXF42018.1 - 0.027 14.0 0.0 0.085 12.4 0.0 1.9 1 0 0 1 1 1 0 EF hand Glyoxalase_6 PF18029.1 PXF42018.1 - 0.043 14.6 0.0 0.12 13.2 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 PXF42018.1 - 0.16 11.9 0.0 23 4.9 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain tRNA-synt_1 PF00133.22 PXF42019.1 - 7.7e-34 116.9 0.0 9.4e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF42019.1 - 3.9e-06 25.9 0.0 5.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PXF42019.1 - 0.0059 16.0 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF42019.1 - 0.0091 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 PXF42020.1 - 2.9e-30 105.1 0.5 3.1e-30 105.0 0.5 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF42020.1 - 0.034 12.9 0.0 0.036 12.8 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF42021.1 - 7.7e-57 192.9 0.0 8.5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF42021.1 - 0.0097 14.7 0.0 0.041 12.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) DUF2009 PF09418.10 PXF42022.1 - 5.1e-197 655.4 0.0 5.8e-197 655.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) CGI-121 PF08617.10 PXF42023.1 - 2.1e-28 99.5 0.5 2.3e-28 99.3 0.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 NAD_binding_10 PF13460.6 PXF42024.1 - 1.8e-17 63.9 0.1 3.6e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PXF42024.1 - 0.00055 19.2 0.0 1 8.5 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein NmrA PF05368.13 PXF42024.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 PXF42024.1 - 0.074 12.5 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family VirionAssem_T7 PF11653.8 PXF42025.1 - 0.052 14.1 2.2 0.11 13.1 2.2 1.5 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein phiKZ_IP PF12699.7 PXF42025.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins VirionAssem_T7 PF11653.8 PXF42026.1 - 0.052 14.1 2.2 0.11 13.1 2.2 1.5 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein phiKZ_IP PF12699.7 PXF42026.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins bZIP_1 PF00170.21 PXF42029.1 - 4.1e-05 23.6 11.0 6.3e-05 23.0 11.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF42029.1 - 0.00071 19.6 10.3 0.0011 19.0 10.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper TAF1D PF15333.6 PXF42029.1 - 0.076 12.7 4.1 0.11 12.2 4.1 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D SOG2 PF10428.9 PXF42029.1 - 0.55 9.4 18.1 0.67 9.1 18.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.9 PXF42029.1 - 1.2 8.7 15.8 2.1 7.9 15.8 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 PXF42029.1 - 5 7.0 11.8 6.7 6.6 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Anoctamin PF04547.12 PXF42030.1 - 5e-103 345.3 4.1 6e-103 345.1 4.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PXF42030.1 - 0.00097 18.9 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 PXF42030.1 - 0.0044 16.4 1.1 0.011 15.1 1.1 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF368 PF04018.13 PXF42030.1 - 0.9 9.1 6.2 7 6.1 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF368) DnaJ_C PF01556.18 PXF42032.1 - 2.9e-19 69.6 0.0 3.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF42032.1 - 2e-16 59.8 0.0 3.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain UbiA PF01040.18 PXF42033.1 - 6e-38 130.6 14.5 7.6e-38 130.2 14.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family EutK_C PF16365.5 PXF42033.1 - 0.39 10.8 1.4 5.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus BK_channel_a PF03493.18 PXF42034.1 - 3.2e-13 49.7 0.0 1.7e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PXF42034.1 - 6.7e-11 42.0 10.0 5.1e-10 39.2 9.8 2.6 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 PXF42034.1 - 0.00024 21.4 0.4 0.023 14.9 0.1 3.0 2 1 1 3 3 3 1 TrkA-N domain ALG11_N PF15924.5 PXF42035.1 - 9.8e-59 198.9 0.0 1.5e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 PXF42035.1 - 4.6e-28 97.9 0.1 6.8e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF42035.1 - 6.4e-18 65.5 0.4 1.2e-17 64.6 0.2 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PXF42035.1 - 2.7e-07 30.9 0.1 6.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Uma2 PF05685.12 PXF42036.1 - 5.7e-08 32.5 0.0 3.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Putative restriction endonuclease WSK PF03832.13 PXF42036.1 - 0.094 12.4 0.6 0.17 11.6 0.6 1.4 1 0 0 1 1 1 0 WSK motif AAA PF00004.29 PXF42038.1 - 3.2e-39 134.4 0.0 5.9e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PXF42038.1 - 4e-19 68.3 0.2 9.3e-19 67.1 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PXF42038.1 - 2.4e-07 30.4 0.1 5.6e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PXF42038.1 - 2.6e-06 27.9 0.5 0.0036 17.7 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 PXF42038.1 - 7.4e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PXF42038.1 - 2.5e-05 24.4 0.1 9.9e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PXF42038.1 - 3.3e-05 23.7 0.0 9.6e-05 22.2 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF42038.1 - 0.0013 19.0 1.3 0.11 12.8 0.0 2.7 2 1 1 3 3 2 1 AAA domain JIP_LZII PF16471.5 PXF42038.1 - 0.004 17.3 3.7 0.011 15.8 3.7 1.8 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II PhoH PF02562.16 PXF42038.1 - 0.009 15.5 0.1 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 PXF42038.1 - 0.0092 16.1 0.2 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain TMF_TATA_bd PF12325.8 PXF42038.1 - 0.013 15.7 1.4 0.019 15.2 0.2 1.8 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding Mg_chelatase PF01078.21 PXF42038.1 - 0.016 14.6 0.1 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 PXF42038.1 - 0.023 13.9 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 PXF42038.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 PXF42038.1 - 0.038 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 PXF42038.1 - 0.048 13.5 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLZ PF16526.5 PXF42038.1 - 0.063 13.6 2.8 0.22 11.9 2.8 1.9 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_24 PF13479.6 PXF42038.1 - 0.065 13.0 0.7 0.19 11.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 PXF42038.1 - 0.07 13.2 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor AAA_11 PF13086.6 PXF42038.1 - 0.086 12.6 0.3 6.9 6.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PXF42038.1 - 0.095 13.2 0.1 0.54 10.8 0.0 2.3 2 2 1 3 3 2 0 AAA domain RNA_helicase PF00910.22 PXF42038.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.25 PXF42039.1 - 9.5e-40 136.6 0.0 1.9e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42039.1 - 2.6e-38 131.8 0.0 5.8e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF42039.1 - 0.0031 16.9 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 PXF42039.1 - 0.0033 17.4 1.6 0.49 10.5 0.1 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat zf-RING_UBOX PF13445.6 PXF42039.1 - 0.0067 16.4 3.0 0.0067 16.4 3.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger DiS_P_DiS PF06750.13 PXF42039.1 - 0.04 14.0 0.9 0.12 12.5 0.9 1.7 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-RING_5 PF14634.6 PXF42039.1 - 0.1 12.6 8.5 0.017 15.1 4.3 2.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 PXF42039.1 - 0.41 11.0 9.0 0.033 14.5 2.4 2.4 2 0 0 2 2 2 0 Ring finger domain FYVE PF01363.21 PXF42039.1 - 1.4 9.1 4.1 0.65 10.2 1.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 PXF42039.1 - 2 8.6 7.0 0.84 9.8 1.7 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF1138 PF06592.13 PXF42040.1 - 2e-07 30.9 4.8 2.4e-07 30.7 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1138) COX4 PF02936.14 PXF42040.1 - 0.0014 18.6 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Adaptin_N PF01602.20 PXF42041.1 - 7.8e-64 216.1 6.8 1e-63 215.7 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 PXF42041.1 - 0.062 13.6 0.5 8.6 6.9 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat DUF3225 PF11533.8 PXF42041.1 - 0.074 12.8 0.0 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) Cnd1 PF12717.7 PXF42041.1 - 0.083 12.9 2.6 1.6 8.8 0.2 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 PXF42042.1 - 1.8e-10 41.1 0.0 4.9e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Adaptin_N PF01602.20 PXF42042.1 - 0.00042 19.0 0.0 0.082 11.4 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region DUF5383 PF17355.2 PXF42043.1 - 0.18 12.2 0.0 7.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) A_deaminase PF00962.22 PXF42044.1 - 1e-32 113.8 0.0 1.4e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase ACT_6 PF13740.6 PXF42045.1 - 6.4e-16 58.1 0.1 1e-10 41.4 0.0 2.6 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 PXF42045.1 - 5.8e-10 38.8 0.0 6.9e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 PXF42045.1 - 1.1e-07 32.3 0.0 0.0093 16.5 0.0 2.4 2 0 0 2 2 2 2 ACT domain CLTH PF10607.9 PXF42046.1 - 1.1e-23 83.8 0.0 2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 PXF42046.1 - 4.8e-22 78.3 0.1 7.2e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 PXF42046.1 - 8.3e-05 22.4 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 LisH Peptidase_S9_N PF02897.15 PXF42047.1 - 6.9e-81 272.2 1.7 9.4e-81 271.7 1.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PXF42047.1 - 1.2e-59 201.4 0.0 3e-59 200.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2850 PF11012.8 PXF42047.1 - 0.12 12.7 0.1 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) SAC3_GANP PF03399.16 PXF42048.1 - 9.4e-10 38.3 0.6 1.3e-09 37.8 0.6 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF1678 PF07913.11 PXF42048.1 - 0.053 13.3 0.7 0.13 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) zf-HIT PF04438.16 PXF42049.1 - 1.8 8.5 16.3 0.25 11.2 11.7 2.0 2 0 0 2 2 2 0 HIT zinc finger FolB PF02152.18 PXF42050.1 - 1e-28 100.1 0.0 1.2e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase cNMP_binding PF00027.29 PXF42051.1 - 2.8e-08 33.7 0.0 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain V_ATPase_I PF01496.19 PXF42052.1 - 7.4 4.4 6.5 10 3.9 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-HIT PF04438.16 PXF42054.1 - 0.03 14.2 9.8 0.059 13.3 9.8 1.5 1 0 0 1 1 1 0 HIT zinc finger ATP_transf PF09830.9 PXF42055.1 - 2.1e-19 69.4 0.1 5.8e-19 68.0 0.1 1.8 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 PXF42055.1 - 0.0048 16.2 0.1 0.049 12.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) DUF3828 PF12883.7 PXF42055.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) DNA_pol_B_palm PF14792.6 PXF42057.1 - 3.7e-23 81.9 0.0 6.5e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 PXF42057.1 - 1.8e-14 53.3 0.0 5.5e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 PXF42057.1 - 4e-10 39.9 0.1 1.2e-09 38.4 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 PXF42057.1 - 0.00014 22.0 0.3 0.0017 18.5 0.3 2.4 1 1 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.6 PXF42057.1 - 0.00071 20.1 0.0 0.002 18.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 PXF42057.1 - 0.0046 17.2 0.2 0.011 16.0 0.2 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain MG3 PF17791.1 PXF42057.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Macroglobulin domain MG3 Ran-binding PF05508.11 PXF42057.1 - 0.16 10.9 0.1 0.43 9.5 0.0 1.6 2 0 0 2 2 2 0 RanGTP-binding protein PrsW-protease PF13367.6 PXF42058.1 - 2.5e-10 40.1 3.6 2.5e-10 40.1 3.6 2.4 2 1 0 2 2 2 1 PrsW family intramembrane metalloprotease Trep_Strep PF09605.10 PXF42058.1 - 0.00082 19.4 5.8 0.00082 19.4 5.8 2.1 2 0 0 2 2 2 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Gemini_mov PF01708.16 PXF42058.1 - 0.012 15.4 2.7 1.6 8.6 0.0 2.9 2 0 0 2 2 2 0 Geminivirus putative movement protein C2 PF00168.30 PXF42059.1 - 0.026 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 C2 domain HAD_2 PF13419.6 PXF42060.1 - 1.3e-22 80.8 0.0 1.6e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF42060.1 - 8.3e-18 65.4 0.0 2.3e-13 50.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF42060.1 - 7.1e-05 23.3 0.0 9.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF42060.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 PXF42060.1 - 0.0056 16.8 0.0 0.75 9.9 0.0 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PTH2 PF01981.16 PXF42061.1 - 1.9e-14 53.9 0.0 2.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3552 PF12072.8 PXF42062.1 - 0.0097 15.3 5.9 0.0097 15.3 5.9 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3552) HALZ PF02183.18 PXF42062.1 - 0.013 15.8 5.0 7.1 6.9 0.4 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 PXF42062.1 - 0.69 8.7 5.9 4 6.2 5.9 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 PXF42062.1 - 3.4 7.9 5.7 4.3 7.6 0.9 2.8 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Atg14 PF10186.9 PXF42062.1 - 7 5.6 27.6 0.73 8.9 4.2 3.6 2 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 tRNA_bind PF01588.20 PXF42063.1 - 2e-20 72.7 0.0 3.1e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain C2 PF00168.30 PXF42067.1 - 8.1e-13 48.6 0.0 4.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain Peptidase_S49 PF01343.18 PXF42068.1 - 2.5e-51 173.6 0.1 1.4e-33 116.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S49 Glyco_transf_64 PF09258.10 PXF42069.1 - 2.4e-43 148.2 0.0 3.3e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 PXF42069.1 - 1e-07 31.8 0.9 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 Fe_bilin_red PF05996.12 PXF42070.1 - 4.2e-62 209.8 0.2 5.4e-62 209.4 0.2 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase TPR_14 PF13428.6 PXF42071.1 - 6.9e-14 51.4 24.6 0.14 13.0 0.6 11.2 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42071.1 - 3.8e-07 29.7 9.3 0.7 10.2 0.0 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 PXF42071.1 - 5e-06 25.9 11.6 6.7e-05 22.2 0.3 4.9 4 2 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42071.1 - 2.6e-05 24.1 7.8 0.34 11.2 0.0 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF42071.1 - 0.00074 19.3 2.7 4.8 7.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF42071.1 - 0.003 17.5 5.7 11 6.0 0.1 5.8 5 3 0 5 5 5 0 Mad3/BUB1 homology region 1 Suf PF05843.14 PXF42071.1 - 0.0048 16.9 6.1 4.6 7.1 0.1 5.2 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_1 PF00515.28 PXF42071.1 - 0.021 14.7 0.1 24 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42071.1 - 0.024 14.6 5.4 0.61 10.3 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF42071.1 - 0.026 14.8 0.0 1.7 8.9 0.0 3.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PXF42071.1 - 0.027 15.0 3.0 13 6.4 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 PXF42071.1 - 0.044 14.2 0.8 1.7e+02 2.9 0.0 5.5 6 1 1 7 7 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 PXF42071.1 - 0.053 13.7 0.2 31 4.9 0.0 4.4 5 0 0 5 5 4 0 PPR repeat family TPR_6 PF13174.6 PXF42071.1 - 0.055 14.1 7.2 64 4.5 0.0 6.2 7 1 1 8 8 5 0 Tetratricopeptide repeat HAT PF02184.16 PXF42071.1 - 0.12 12.4 9.4 20 5.2 0.8 5.9 5 1 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 PXF42071.1 - 0.14 12.9 20.0 0.49 11.1 1.0 6.6 6 2 2 8 8 7 0 Tetratricopeptide repeat RNA_pol_L_2 PF13656.6 PXF42071.1 - 0.19 11.5 0.1 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain USP8_dimer PF08969.11 PXF42071.1 - 0.47 10.7 2.2 4.2 7.6 0.0 3.3 3 0 0 3 3 3 0 USP8 dimerisation domain JAKMIP_CC3 PF16034.5 PXF42073.1 - 0.07 13.1 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain ORF6C PF10552.9 PXF42073.1 - 0.1 12.7 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 ORF6C domain CwfJ_C_2 PF04676.14 PXF42074.1 - 0.14 13.0 1.6 0.24 12.3 1.6 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 DUF5384 PF17358.2 PXF42075.1 - 0.011 15.8 5.8 0.018 15.1 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) MgtC PF02308.16 PXF42076.1 - 2.8e-25 89.0 17.2 3.4e-25 88.7 17.2 1.0 1 0 0 1 1 1 1 MgtC family Fringe PF02434.16 PXF42077.1 - 1e-09 38.2 0.0 3.6e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 PXF42077.1 - 0.002 17.6 0.2 0.0034 16.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 PXF42077.1 - 0.052 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase bZIP_1 PF00170.21 PXF42079.1 - 5.5e-06 26.4 13.2 5.5e-06 26.4 13.2 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF42079.1 - 0.0086 16.1 13.5 0.0086 16.1 13.5 2.5 1 1 1 2 2 1 1 Basic region leucine zipper Nsp1_C PF05064.13 PXF42079.1 - 0.015 15.1 2.1 0.025 14.4 2.1 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region bZIP_Maf PF03131.17 PXF42079.1 - 0.036 14.6 21.7 0.089 13.3 12.8 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor ADP_ribosyl_GH PF03747.14 PXF42079.1 - 0.13 12.0 0.5 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Cnn_1N PF07989.11 PXF42079.1 - 0.19 11.9 9.5 0.53 10.5 9.5 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 WDCP PF15390.6 PXF42079.1 - 0.2 10.0 5.2 0.24 9.8 5.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF2244 PF10003.9 PXF42079.1 - 0.47 10.1 4.0 0.84 9.3 4.0 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) XRN_M PF17846.1 PXF42079.1 - 1.2 8.0 4.0 0.95 8.3 2.6 1.5 1 1 0 1 1 1 0 Xrn1 helical domain DUF4164 PF13747.6 PXF42079.1 - 4 7.8 19.3 12 6.2 5.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.22 PXF42079.1 - 7.4 6.8 14.0 0.13 12.5 3.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BSD PF03909.17 PXF42080.1 - 1.9e-07 31.0 0.1 7.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 BSD domain DUF4611 PF15387.6 PXF42080.1 - 3.7 7.8 10.5 2 8.7 2.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) His_Phos_2 PF00328.22 PXF42081.1 - 1.2e-22 80.8 0.0 8.3e-19 68.2 0.0 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Condensin2nSMC PF12422.8 PXF42082.1 - 7.2e-30 104.1 0.2 6.1e-29 101.1 0.1 2.5 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 PXF42082.1 - 4.3e-05 23.4 3.3 0.58 10.6 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 PXF42082.1 - 0.00018 21.8 1.3 0.057 13.8 0.1 3.8 2 1 1 3 3 3 1 HEAT repeats Adaptin_N PF01602.20 PXF42082.1 - 0.0013 17.4 0.0 0.0035 16.0 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PXF42082.1 - 0.0077 16.3 0.4 0.45 10.5 0.0 3.5 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tub_N PF16322.5 PXF42082.1 - 0.093 13.1 1.4 0.28 11.6 1.4 1.8 1 0 0 1 1 1 0 Tubby N-terminal Cohesin_HEAT PF12765.7 PXF42082.1 - 0.17 12.2 1.6 0.46 10.8 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SIR2 PF02146.17 PXF42083.1 - 8.1e-14 51.9 0.0 1.6e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF1415 PF07209.12 PXF42085.1 - 2.4e-38 131.6 0.0 2.9e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) Ank_2 PF12796.7 PXF42086.1 - 7.4e-81 266.8 27.9 1.4e-12 48.1 0.6 10.9 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF42086.1 - 3.5e-76 250.7 25.9 1.8e-08 34.7 0.0 15.1 9 4 8 17 17 17 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 PXF42086.1 - 8.8e-75 245.8 27.4 1.1e-09 38.3 0.2 14.1 9 2 5 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF42086.1 - 7.6e-64 204.1 24.2 1.3e-05 25.2 0.1 19.3 20 0 0 20 20 20 11 Ankyrin repeat Ank PF00023.30 PXF42086.1 - 1.3e-59 196.2 31.3 4.3e-06 26.9 0.0 17.8 20 1 0 20 20 17 12 Ankyrin repeat zf-RING_2 PF13639.6 PXF42086.1 - 8.3e-10 38.9 3.9 2.4e-09 37.4 3.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF42086.1 - 5.8e-08 32.4 4.1 9.1e-08 31.7 1.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PXF42086.1 - 2.5e-07 30.4 2.2 6.6e-07 29.1 2.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF42086.1 - 6.8e-07 29.0 4.3 2.4e-06 27.3 4.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF42086.1 - 8e-05 22.9 2.4 0.00028 21.1 2.4 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PXF42086.1 - 0.00022 21.2 0.6 0.00022 21.2 0.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF42086.1 - 0.00036 20.5 1.4 0.0011 19.0 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF42086.1 - 0.00073 19.4 2.1 0.00073 19.4 2.1 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF42086.1 - 0.017 15.0 2.1 0.044 13.6 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AnkUBD PF18418.1 PXF42086.1 - 0.018 15.1 0.0 5 7.3 0.0 4.3 4 1 1 5 5 5 0 Ankyrin ubiquitin-binding domain zf-RING-like PF08746.11 PXF42086.1 - 0.054 13.8 2.0 0.24 11.7 2.0 2.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 PXF42086.1 - 0.074 13.2 1.0 0.31 11.2 1.0 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 PXF42086.1 - 0.5 10.3 3.7 1.3 9.0 3.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 BT1 PF03092.16 PXF42087.1 - 8.5e-94 314.6 14.8 5.2e-49 166.8 4.3 3.0 1 1 1 2 2 2 2 BT1 family NAD_binding_10 PF13460.6 PXF42088.1 - 7.4e-26 91.2 0.0 2.4e-25 89.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF42088.1 - 5.4e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF42088.1 - 5.1e-08 32.7 0.0 2e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF42088.1 - 4.9e-05 22.9 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PXF42088.1 - 0.0019 17.4 0.1 0.044 12.9 0.0 2.6 2 1 1 3 3 3 1 RmlD substrate binding domain adh_short PF00106.25 PXF42088.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 PXF42088.1 - 0.062 12.4 0.1 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PXF42088.1 - 0.27 10.4 1.2 7.4 5.6 0.0 2.8 2 1 1 3 3 3 0 Male sterility protein Rhodanese PF00581.20 PXF42089.1 - 0.0066 16.9 0.0 0.018 15.5 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Sharpin_PH PF16764.5 PXF42090.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Sharpin PH domain SVS_QK PF10578.9 PXF42090.1 - 0.1 13.2 1.4 0.1 13.2 1.4 1.7 2 0 0 2 2 2 0 Seminal vesicle protein repeat Bromodomain PF00439.25 PXF42092.1 - 5.1e-11 42.5 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Alkyl_sulf_dimr PF14863.6 PXF42092.1 - 0.035 14.6 0.2 0.088 13.3 0.2 1.6 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Agenet PF05641.12 PXF42092.1 - 0.056 13.9 0.5 0.17 12.4 0.5 1.8 1 0 0 1 1 1 0 Agenet domain Abhydrolase_3 PF07859.13 PXF42093.1 - 1.3e-15 57.9 0.3 2.2e-15 57.1 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF42093.1 - 2.5e-05 23.6 0.7 0.00031 20.1 0.1 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF42093.1 - 0.0011 19.6 1.2 0.0011 19.6 1.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF42093.1 - 0.0027 17.4 0.0 0.013 15.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PXF42093.1 - 0.0032 16.4 0.1 0.2 10.5 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DUF900 PF05990.12 PXF42093.1 - 0.011 15.2 0.1 0.038 13.5 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 PXF42093.1 - 0.037 13.7 0.1 0.079 12.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 PXF42093.1 - 0.039 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 PXF42093.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) NDUFA12 PF05071.16 PXF42094.1 - 4.1e-09 37.2 0.4 6.8e-09 36.5 0.4 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 HSP90 PF00183.18 PXF42095.1 - 1.7e-156 522.1 3.3 1.7e-156 522.1 3.3 2.6 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 PXF42095.1 - 8.1e-11 41.9 1.3 1.3e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PXF42095.1 - 1.2e-09 38.7 0.0 2.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1068 PF06364.12 PXF42095.1 - 0.2 11.5 0.9 0.41 10.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Prominin PF05478.11 PXF42096.1 - 0.0017 16.5 2.1 0.0025 15.9 2.1 1.1 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 PXF42096.1 - 0.0045 17.0 8.0 0.05 13.7 0.5 3.0 2 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus MerR-DNA-bind PF09278.11 PXF42096.1 - 0.11 13.1 2.0 0.6 10.7 0.8 2.7 2 0 0 2 2 2 0 MerR, DNA binding CDC27 PF09507.10 PXF42096.1 - 0.17 11.3 36.8 0.25 10.7 36.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Choline_kinase PF01633.20 PXF42097.1 - 3.1e-46 157.6 0.0 4.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PXF42097.1 - 4.7e-12 46.4 0.0 8.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF42097.1 - 0.076 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 PXF42097.1 - 0.2 11.0 0.1 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Haspin_kinase PF12330.8 PXF42097.1 - 0.2 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L38e PF01781.18 PXF42098.1 - 5.9e-34 116.0 1.8 6.4e-34 115.9 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Translin PF01997.16 PXF42099.1 - 2.8e-22 79.7 0.0 3.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Translin family Mito_carr PF00153.27 PXF42100.1 - 5.6e-59 196.1 4.0 2.3e-21 75.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Rio2_N PF09202.11 PXF42100.1 - 0.0026 18.0 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal Myb_DNA-binding PF00249.31 PXF42101.1 - 9.3e-07 28.9 0.1 0.077 13.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ecm29 PF13001.7 PXF42101.1 - 0.017 13.8 1.9 0.021 13.6 0.9 1.6 2 0 0 2 2 2 0 Proteasome stabiliser Myb_DNA-bind_6 PF13921.6 PXF42101.1 - 0.17 12.2 3.5 2.5 8.4 0.1 3.5 3 1 0 3 3 3 0 Myb-like DNA-binding domain HAUS-augmin3 PF14932.6 PXF42101.1 - 0.17 11.4 1.7 0.57 9.7 1.7 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Rad52_Rad22 PF04098.15 PXF42102.1 - 1.1e-42 145.5 0.0 2.3e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein FlgT_N PF16548.5 PXF42102.1 - 0.16 12.6 0.1 0.16 12.6 0.1 3.4 4 1 0 4 4 4 0 Flagellar assembly protein T, N-terminal domain Peptidase_M66 PF10462.9 PXF42102.1 - 1 8.2 7.8 3.7 6.4 1.3 2.2 2 0 0 2 2 2 0 Peptidase M66 Aminotran_5 PF00266.19 PXF42103.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4922 PF16269.5 PXF42103.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) Med9 PF07544.13 PXF42105.1 - 0.02 14.9 0.6 0.03 14.4 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HAD_2 PF13419.6 PXF42105.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PPR_2 PF13041.6 PXF42106.1 - 1e-97 320.2 22.4 1.7e-14 53.7 0.1 10.5 2 2 8 10 10 10 10 PPR repeat family PPR_1 PF12854.7 PXF42106.1 - 2.1e-80 264.1 16.3 2.1e-09 36.9 0.0 12.1 11 2 0 11 11 11 10 PPR repeat PPR_3 PF13812.6 PXF42106.1 - 1.3e-77 255.8 8.8 9.1e-15 54.5 0.0 7.8 4 3 5 9 9 9 9 Pentatricopeptide repeat domain PPR PF01535.20 PXF42106.1 - 2.3e-64 209.2 20.2 2.3e-07 30.6 0.0 12.5 11 2 0 11 11 11 10 PPR repeat PPR_long PF17177.4 PXF42106.1 - 1.6e-42 145.3 7.0 9e-14 51.3 0.1 4.9 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 PXF42106.1 - 1.1e-06 27.9 1.7 0.64 9.1 0.0 5.6 3 3 3 7 7 7 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.6 PXF42106.1 - 2.7e-05 24.6 7.6 37 5.5 0.4 9.0 9 2 2 11 11 10 0 Tetratricopeptide repeat MRP-S27 PF10037.9 PXF42106.1 - 0.00023 20.1 0.2 0.15 10.8 0.0 3.0 3 1 1 4 4 4 2 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 PXF42106.1 - 0.0013 18.6 4.3 7.4 6.4 0.0 4.9 4 2 1 6 6 6 2 Region in Clathrin and VPS BKACE PF05853.12 PXF42106.1 - 0.0047 16.3 0.2 5.8 6.1 0.0 3.8 2 1 2 4 4 4 1 beta-keto acid cleavage enzyme RPM2 PF08579.11 PXF42106.1 - 0.0098 16.3 0.4 8.1 6.9 0.0 4.5 2 2 2 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) RabGAP-TBC PF00566.18 PXF42106.1 - 0.011 15.4 0.0 0.91 9.1 0.0 3.5 3 2 1 4 4 4 0 Rab-GTPase-TBC domain LPD11 PF18824.1 PXF42106.1 - 0.12 12.5 0.0 0.95 9.6 0.0 2.6 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 Radical_SAM PF04055.21 PXF42106.1 - 0.14 12.5 0.0 1.7 9.0 0.0 2.4 1 1 1 2 2 2 0 Radical SAM superfamily BTAD PF03704.17 PXF42106.1 - 5.7 7.4 7.3 1.6 9.2 0.1 3.3 4 0 0 4 4 4 0 Bacterial transcriptional activator domain FA_desaturase PF00487.24 PXF42108.1 - 8.7e-36 124.0 9.4 8.7e-36 124.0 9.4 2.9 2 1 1 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 PXF42108.1 - 4.5e-23 81.2 0.0 3.9e-22 78.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.21 PXF42110.1 - 2.7e-09 37.0 9.5 5.9e-09 35.9 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF42110.1 - 0.00044 20.3 13.6 0.0009 19.3 13.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF42110.1 - 0.018 15.5 11.4 0.045 14.3 11.4 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor TGT_C2 PF14810.6 PXF42110.1 - 0.025 14.7 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Glyco_tranf_2_4 PF13704.6 PXF42111.1 - 5.9e-07 29.9 0.0 3.8e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ribosomal_L2_C PF03947.18 PXF42113.1 - 1.9e-48 163.8 2.8 3.1e-48 163.2 2.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PXF42113.1 - 3e-15 55.9 0.1 8e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Proteasome PF00227.26 PXF42114.1 - 6.6e-59 198.6 0.1 8.3e-59 198.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF42114.1 - 1.8e-14 53.1 0.1 3.4e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sel1 PF08238.12 PXF42115.1 - 3.4e-87 284.9 56.7 2.4e-06 28.0 0.0 24.2 26 0 0 26 26 26 19 Sel1 repeat TPR_7 PF13176.6 PXF42115.1 - 1.7e-05 24.5 21.5 2.5 8.3 0.3 11.1 12 1 1 13 13 13 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF42115.1 - 0.00022 21.8 34.4 0.71 10.6 0.8 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 PXF42115.1 - 0.00031 21.2 33.1 2 9.0 0.1 12.9 15 1 1 16 16 16 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF42115.1 - 0.0022 18.1 13.9 0.4 10.9 0.0 7.4 5 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PXF42115.1 - 0.0051 17.4 39.0 26 5.7 0.2 16.0 21 0 0 21 21 21 0 Tetratricopeptide repeat DUF1376 PF07120.11 PXF42115.1 - 0.011 16.0 0.9 20 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) TPR_2 PF07719.17 PXF42115.1 - 0.096 12.8 0.2 0.096 12.8 0.2 12.1 15 1 0 15 15 15 0 Tetratricopeptide repeat ANTAR PF03861.14 PXF42115.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 ANTAR domain WXG100 PF06013.12 PXF42116.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF42116.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF42116.1 - 0.41 11.4 5.2 0.8 10.4 5.2 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain L27_2 PF09045.10 PXF42117.1 - 0.081 12.9 1.1 0.081 12.9 1.1 1.8 1 1 0 1 1 1 0 L27_2 CAF-1_p150 PF11600.8 PXF42117.1 - 1.1 9.0 12.5 0.42 10.3 2.3 2.0 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.9 PXF42117.1 - 3.2 6.8 7.6 3.3 6.7 7.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HHH_9 PF17674.1 PXF42119.1 - 0.03 15.2 0.1 0.065 14.2 0.1 1.5 1 0 0 1 1 1 0 HHH domain BtpA PF03437.15 PXF42120.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 BtpA family NAM-associated PF14303.6 PXF42121.1 - 0.00019 22.2 4.4 0.00025 21.8 4.4 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain RNA_polI_A34 PF08208.11 PXF42121.1 - 0.1 12.7 10.8 0.14 12.3 10.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NAM-associated PF14303.6 PXF42122.1 - 0.016 16.0 6.4 0.069 13.9 6.4 2.1 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PNKP-ligase_C PF16536.5 PXF42122.1 - 0.11 12.8 0.4 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Transferase PF02458.15 PXF42122.1 - 0.15 10.7 1.8 0.18 10.4 1.8 1.1 1 0 0 1 1 1 0 Transferase family NHL PF01436.21 PXF42123.1 - 0.041 13.9 0.2 11 6.3 0.0 4.1 3 0 0 3 3 3 0 NHL repeat DUF4971 PF16341.5 PXF42123.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Spem1 PF15670.5 PXF42123.1 - 2.5 7.6 7.7 4.4 6.8 7.7 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Glyco_tranf_2_4 PF13704.6 PXF42124.1 - 8.9e-10 39.0 2.1 2.9e-09 37.3 0.3 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PXF42124.1 - 1.2e-05 25.1 0.7 1.2e-05 25.1 0.7 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 92 Xpo1 PF08389.12 PXF42125.1 - 1.2e-12 48.1 0.0 3.5e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Exportin 1-like protein DEP PF00610.21 PXF42126.1 - 2e-12 47.0 0.0 4.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PI3_PI4_kinase PF00454.27 PXF42126.1 - 1.7e-05 24.8 0.0 0.00041 20.2 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 PXF42126.1 - 0.02 14.3 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) DUF1475 PF07343.11 PXF42127.1 - 3.3e-05 23.8 6.3 4.9e-05 23.3 6.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) Meckelin PF09773.9 PXF42127.1 - 0.11 10.6 2.3 0.051 11.7 0.3 1.3 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) BRK PF07533.16 PXF42128.1 - 5.5e-08 32.3 0.0 1.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 BRK domain GCD14 PF08704.10 PXF42129.1 - 2e-66 224.2 0.0 5e-66 222.9 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 PXF42129.1 - 2.1e-08 34.2 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PXF42129.1 - 4.4e-06 26.6 0.0 6.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PXF42129.1 - 5.9e-05 24.0 0.1 0.00019 22.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF42129.1 - 0.00039 21.1 0.0 0.00074 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF42129.1 - 0.0019 18.8 0.1 0.0044 17.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 PXF42129.1 - 0.033 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_3 PF01596.17 PXF42129.1 - 0.038 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.17 PXF42129.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cys_Met_Meta_PP PF01053.20 PXF42131.1 - 3.6e-77 259.5 0.0 4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PXF42131.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Thioredoxin PF00085.20 PXF42132.1 - 7.3e-07 29.1 0.0 7.6e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF42132.1 - 0.024 15.1 0.0 0.027 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 PXF42132.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 PXF42132.1 - 0.18 11.7 0.0 0.19 11.6 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 PXF42133.1 - 1.5e-17 63.5 0.0 1.8e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PXF42133.1 - 3.6e-05 24.0 0.0 0.0019 18.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 PXF42133.1 - 0.00034 20.4 0.0 0.00043 20.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF42133.1 - 0.0012 18.3 0.1 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PXF42133.1 - 0.0096 16.4 0.0 0.078 13.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 PXF42133.1 - 0.043 13.6 0.0 0.043 13.6 0.0 2.0 1 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 PXF42133.1 - 0.054 13.6 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain SNF PF00209.18 PXF42134.1 - 5.7e-96 322.3 42.0 4.6e-62 210.4 18.7 2.5 2 1 1 3 3 3 2 Sodium:neurotransmitter symporter family TMEM213 PF15192.6 PXF42134.1 - 0.0049 16.8 7.1 0.4 10.7 0.3 3.4 3 0 0 3 3 3 3 TMEM213 family AdoHcyase PF05221.17 PXF42135.1 - 3.8e-87 292.2 0.0 4.7e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PXF42135.1 - 2.4e-63 213.0 1.8 3.5e-63 212.5 1.8 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF42135.1 - 2.3e-07 30.4 0.4 4.4e-07 29.4 0.4 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PXF42135.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 PXF42135.1 - 0.0021 18.5 0.1 0.0042 17.5 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 PXF42135.1 - 0.0034 17.4 0.2 0.007 16.4 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 PXF42135.1 - 0.01 16.1 0.0 0.032 14.5 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain PALP PF00291.25 PXF42135.1 - 0.044 13.2 0.7 0.2 11.1 0.3 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Urocanase PF01175.18 PXF42135.1 - 0.09 12.4 0.6 0.15 11.7 0.6 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain ELFV_dehydrog PF00208.21 PXF42135.1 - 0.098 12.4 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase OrsD PF12013.8 PXF42138.1 - 1e-09 38.8 1.5 1.6e-09 38.2 1.5 1.3 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 PXF42138.1 - 1e-06 29.0 1.4 0.00047 20.4 1.3 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PXF42138.1 - 0.012 16.4 4.7 1.4 10.0 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF42138.1 - 0.13 12.8 5.2 5.6 7.6 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type UPF0547 PF10571.9 PXF42138.1 - 0.14 12.3 0.2 0.14 12.3 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf_C2H2_ZHX PF18387.1 PXF42138.1 - 0.15 11.7 2.9 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 PXF42138.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-NADH-PPase PF09297.11 PXF42138.1 - 0.39 10.4 2.4 8.3 6.2 0.1 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain SHOCT PF09851.9 PXF42139.1 - 0.011 15.5 0.6 0.03 14.1 0.0 2.2 2 0 0 2 2 2 0 Short C-terminal domain An_peroxidase PF03098.15 PXF42140.1 - 2.7e-117 392.6 0.3 3.2e-117 392.3 0.3 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF42141.1 - 1.4e-115 386.9 0.0 1.8e-115 386.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF42142.1 - 1.4e-115 386.9 0.0 1.8e-115 386.5 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Mei5 PF10376.9 PXF42143.1 - 0.0099 15.8 2.0 0.062 13.1 3.0 1.7 2 0 0 2 2 2 1 Double-strand recombination repair protein An_peroxidase PF03098.15 PXF42144.1 - 2.1e-112 376.4 0.0 2.6e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Motile_Sperm PF00635.26 PXF42145.1 - 4.8e-41 139.0 0.2 2.4e-16 59.5 0.0 3.5 3 1 0 3 3 3 3 MSP (Major sperm protein) domain PapD-like PF14874.6 PXF42145.1 - 0.012 15.8 0.1 0.17 12.1 0.0 2.7 3 0 0 3 3 3 0 Flagellar-associated PapD-like DUF5001 PF16392.5 PXF42145.1 - 0.031 14.2 0.8 0.47 10.4 0.0 2.8 3 1 0 3 3 3 0 Ig-like domain Chromo_2 PF18704.1 PXF42145.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 fn3_5 PF06280.12 PXF42145.1 - 0.17 12.6 0.5 1.3 9.8 0.0 2.5 3 0 0 3 3 3 0 Fn3-like domain ADH_zinc_N_2 PF13602.6 PXF42146.1 - 1.3e-21 78.0 1.3 3e-20 73.6 1.3 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PXF42146.1 - 1e-13 51.4 1.7 2.6e-13 50.1 0.8 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PXF42146.1 - 1.5e-10 40.9 1.3 8.7e-09 35.2 0.2 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PXF42146.1 - 0.0054 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ENTH PF01417.20 PXF42147.1 - 3.5e-27 94.9 0.0 5.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Tmemb_185A PF10269.9 PXF42148.1 - 0.098 12.3 0.2 2.6 7.6 0.0 2.6 2 1 1 3 3 3 0 Transmembrane Fragile-X-F protein MarR_2 PF12802.7 PXF42148.1 - 0.21 11.5 3.4 1.6 8.6 0.4 2.9 3 0 0 3 3 3 0 MarR family Flu_NS1 PF00600.19 PXF42152.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Voltage_CLC PF00654.20 PXF42153.1 - 3.4e-75 253.5 25.0 3.4e-75 253.5 25.0 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 PXF42153.1 - 9.3e-11 42.0 0.2 3.4e-06 27.4 0.1 2.6 2 0 0 2 2 2 2 CBS domain CytB6-F_Fe-S PF08802.10 PXF42153.1 - 0.91 9.6 3.9 1.8 8.6 0.1 3.3 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit SET PF00856.28 PXF42154.1 - 2.6e-16 60.5 0.5 1.7e-15 57.9 0.1 2.7 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 PXF42154.1 - 7.6e-06 26.3 15.2 7.6e-06 26.3 15.2 3.7 4 0 0 4 4 4 1 CXC domain TCR PF03638.15 PXF42154.1 - 0.28 11.5 35.2 1.8 8.9 15.7 2.9 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Pkinase PF00069.25 PXF42155.1 - 5.6e-70 235.7 0.0 6.9e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42155.1 - 3e-35 121.8 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42155.1 - 1e-06 28.3 0.0 9.2e-06 25.2 0.0 2.3 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 PXF42155.1 - 1.6e-05 25.4 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 PXF42155.1 - 3.7e-05 22.7 0.0 5.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF42155.1 - 0.0003 20.2 0.1 0.00058 19.3 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF42155.1 - 0.016 14.8 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 RIO1 family NAD_binding_9 PF13454.6 PXF42155.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Kelch_5 PF13854.6 PXF42157.1 - 2.6e-38 129.4 0.9 6.3e-06 26.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PXF42157.1 - 3.5e-35 119.8 2.4 8.8e-10 38.5 0.0 7.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 PXF42157.1 - 2.6e-34 116.5 4.7 4.1e-10 39.1 0.0 7.0 7 1 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 PXF42157.1 - 1e-28 98.1 9.1 6.7e-07 29.0 0.0 6.8 7 1 0 7 7 7 4 Kelch motif BTB PF00651.31 PXF42157.1 - 1.3e-28 99.4 0.3 5.8e-28 97.4 0.1 2.2 2 1 1 3 3 3 1 BTB/POZ domain Kelch_3 PF13415.6 PXF42157.1 - 1.2e-25 89.3 6.7 0.00032 20.9 0.0 8.8 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF42157.1 - 1.7e-24 85.3 9.8 9.2e-05 22.6 0.1 7.4 6 2 1 7 7 7 5 Kelch motif BACK PF07707.15 PXF42157.1 - 3.6e-05 23.8 0.9 0.00011 22.2 0.3 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ribosomal_L30_N PF08079.12 PXF42158.1 - 1.2e-22 79.9 15.1 2.3e-22 79.0 15.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 PXF42158.1 - 2.7e-21 75.2 2.2 2.8e-21 75.1 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF3752 PF12572.8 PXF42158.1 - 0.11 13.1 2.2 0.2 12.2 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Tipalpha PF16753.5 PXF42158.1 - 0.37 10.6 2.2 8.1 6.3 0.5 2.1 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter DUF3641 PF12345.8 PXF42160.1 - 2.3e-46 157.2 0.0 3.7e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 PXF42160.1 - 5.8e-10 39.8 0.0 9.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 PXF42160.1 - 8.3e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 PXF42160.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Acyltransferase PF01553.21 PXF42161.1 - 1e-15 57.5 0.0 5.2e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase DUF2628 PF10947.8 PXF42161.1 - 0.052 13.9 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) NUDIX PF00293.28 PXF42162.1 - 1.4e-06 28.4 0.2 5.3e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF760 PF05542.11 PXF42163.1 - 1.1e-34 118.6 0.1 2.2e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Surfac_D-trimer PF09006.11 PXF42163.1 - 0.19 11.7 0.3 0.36 10.8 0.3 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation V-SNARE_C PF12352.8 PXF42164.1 - 0.00085 19.6 0.3 0.00085 19.6 0.3 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.11 PXF42164.1 - 0.0026 18.0 7.1 0.18 12.1 1.6 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 PXF42164.1 - 0.015 15.2 2.6 0.21 11.5 0.1 2.4 2 0 0 2 2 2 0 Sec20 P4Ha_N PF08336.11 PXF42164.1 - 0.039 14.0 1.7 6.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF5089 PF17002.5 PXF42164.1 - 0.1 12.5 13.2 0.87 9.4 13.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) DUF4558 PF15104.6 PXF42164.1 - 0.19 11.8 2.8 0.38 10.8 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4558) Laminin_II PF06009.12 PXF42164.1 - 0.4 10.7 8.0 0.91 9.5 1.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PXF42164.1 - 1.5 8.9 4.7 8.3 6.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PXF42164.1 - 1.9 9.0 6.6 3.7 8.1 0.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.11 PXF42164.1 - 2.7 8.0 10.2 0.15 12.1 2.3 2.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3119 PF11317.8 PXF42166.1 - 2e-28 99.2 0.1 2.5e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) Methyltransf_3 PF01596.17 PXF42168.1 - 8.2e-46 155.8 0.0 1.2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 PXF42168.1 - 1.3e-08 35.8 0.1 2.2e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF42168.1 - 6.3e-07 29.2 0.0 8.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 PXF42168.1 - 2.4e-06 27.4 0.1 3.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF42168.1 - 3.3e-06 27.0 0.2 5e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PXF42168.1 - 3.4e-05 24.5 0.1 7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PXF42168.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Glycolytic PF00274.19 PXF42169.1 - 4.8e-129 430.0 0.0 6e-129 429.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF3591 PF12157.8 PXF42169.1 - 0.087 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Ribophorin_II PF05817.14 PXF42169.1 - 0.16 10.4 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II RWP-RK PF02042.15 PXF42170.1 - 1.7e-15 56.7 0.1 3e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_23 PF13384.6 PXF42170.1 - 9.2e-05 22.1 0.2 0.00022 20.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 PXF42170.1 - 0.0003 20.9 0.3 0.0005 20.2 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 PXF42170.1 - 0.0032 17.3 0.1 0.0077 16.1 0.1 1.6 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 PXF42170.1 - 0.0035 16.8 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_3 PF01381.22 PXF42170.1 - 0.0048 16.9 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_28 PF13518.6 PXF42170.1 - 0.0048 17.0 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 PXF42170.1 - 0.0071 16.1 2.2 0.019 14.7 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 PXF42170.1 - 0.013 15.6 0.1 0.035 14.1 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_1 PF00126.27 PXF42170.1 - 0.018 14.9 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.19 PXF42170.1 - 0.04 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 PXF42170.1 - 0.041 14.2 0.0 0.041 14.2 0.0 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_24 PF13412.6 PXF42170.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 PXF42170.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 PXF42170.1 - 0.12 12.1 0.1 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_37 PF13744.6 PXF42170.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0175 PF03683.13 PXF42170.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_6 PF01418.17 PXF42170.1 - 0.14 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_10 PF04967.12 PXF42170.1 - 0.15 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain ChuX_HutX PF06228.13 PXF42171.1 - 0.0016 18.2 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX WW PF00397.26 PXF42172.1 - 8.3e-13 48.2 6.5 2.7e-08 33.8 0.1 3.0 3 0 0 3 3 3 2 WW domain DUF563 PF04577.14 PXF42173.1 - 1.2e-13 51.8 0.1 1.7e-13 51.2 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_tranf_2_4 PF13704.6 PXF42175.1 - 3.6e-08 33.8 0.1 9.3e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PXF42175.1 - 7.5e-07 29.1 1.0 1.3e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 92 WW PF00397.26 PXF42176.1 - 6.4e-14 51.7 5.0 3.8e-09 36.5 0.1 3.0 3 0 0 3 3 3 2 WW domain ubiquitin PF00240.23 PXF42177.1 - 4.2e-07 29.6 0.0 8.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 PXF42177.1 - 8.9e-06 26.3 2.7 1.7e-05 25.4 0.1 3.0 4 0 0 4 4 4 1 WXG100 protein secretion system (Wss), protein YukD Cactin_mid PF10312.9 PXF42177.1 - 0.039 13.7 1.6 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 Conserved mid region of cactin Rad60-SLD_2 PF13881.6 PXF42177.1 - 0.081 13.0 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3684 PF12449.8 PXF42178.1 - 2.2e-139 466.2 1.7 4.4e-101 339.4 0.0 3.3 3 1 0 3 3 3 3 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 PXF42178.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 PXF42178.1 - 0.019 15.0 0.4 0.042 13.9 0.4 1.5 1 0 0 1 1 1 0 WLM domain PRA1 PF03208.19 PXF42179.1 - 2.2e-18 66.2 7.2 3.7e-18 65.5 7.2 1.3 1 0 0 1 1 1 1 PRA1 family protein Ibs_toxin PF13956.6 PXF42179.1 - 0.41 10.7 5.3 0.96 9.5 5.3 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Prenyltrans PF00432.21 PXF42180.1 - 9.6e-37 124.4 15.5 6.7e-08 32.1 0.6 5.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 PXF42180.1 - 8.5e-06 25.1 0.0 0.0053 15.9 0.0 2.7 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 PXF42180.1 - 0.015 14.4 0.0 0.18 10.9 0.0 2.3 1 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain CTP_transf_like PF01467.26 PXF42181.1 - 3.5e-42 144.0 0.1 8.1e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 PXF42181.1 - 1.3e-08 34.8 1.1 2.7e-05 24.1 0.2 3.3 2 1 0 2 2 2 2 FAD synthetase MBOAT_2 PF13813.6 PXF42182.1 - 7.5e-10 38.9 3.2 9.8e-10 38.6 0.5 2.3 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 PXF42182.1 - 5.6e-05 22.7 2.9 7.5e-05 22.2 2.9 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SET PF00856.28 PXF42184.1 - 5.3e-13 49.7 0.0 1.2e-11 45.2 0.0 3.2 2 1 0 2 2 2 1 SET domain zf-4CXXC_R1 PF10497.9 PXF42184.1 - 0.06 13.6 11.9 0.17 12.1 11.9 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Thioredoxin PF00085.20 PXF42185.1 - 2.4e-34 117.4 0.0 9.8e-26 89.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PXF42185.1 - 5.3e-08 33.0 0.0 0.0022 17.9 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PXF42185.1 - 2.9e-05 24.5 0.2 0.027 14.9 0.1 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PXF42185.1 - 4.3e-05 23.0 0.0 0.3 10.4 0.0 2.4 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF42185.1 - 0.0018 18.6 0.0 2.2 8.7 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF42185.1 - 0.0032 17.4 0.0 0.0085 16.0 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PXF42185.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 PXF42185.1 - 0.055 13.4 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 PXF42185.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin BTK PF00779.19 PXF42187.1 - 0.067 13.0 1.3 0.15 11.9 1.3 1.6 1 0 0 1 1 1 0 BTK motif CHORD PF04968.12 PXF42187.1 - 0.17 12.6 5.1 1.3 9.8 0.2 2.5 2 1 0 2 2 2 0 CHORD Ribosomal_L17 PF01196.19 PXF42188.1 - 2.3e-35 121.4 0.2 3e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Complex1_LYR_2 PF13233.6 PXF42189.1 - 7.7e-15 55.4 2.4 9.3e-15 55.1 2.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 PXF42189.1 - 2.3e-09 37.2 3.2 3.4e-09 36.6 3.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PXF42189.1 - 0.0048 17.5 0.9 0.0062 17.1 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3106 PF11304.8 PXF42189.1 - 0.064 13.7 2.9 0.43 11.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF4028 PF13220.6 PXF42189.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) ThiF PF00899.21 PXF42190.1 - 2.7e-15 56.4 0.0 2.6e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 ThiF family DIM1 PF02966.16 PXF42192.1 - 2.5e-56 189.1 0.5 2.9e-56 188.9 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PXF42192.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AATF-Che1 PF13339.6 PXF42193.1 - 5.1e-09 36.9 2.7 1.3e-07 32.4 2.7 2.3 1 1 0 1 1 1 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 PXF42193.1 - 1.9e-08 34.7 0.0 5.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Nkap_C PF06047.11 PXF42195.1 - 1.5e-43 147.1 5.5 1.5e-43 147.1 5.5 2.4 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain ARID PF01388.21 PXF42196.1 - 7.8e-18 64.9 0.0 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.6 PXF42196.1 - 1.4e-11 44.5 0.0 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Macoilin PF09726.9 PXF42196.1 - 3.5 6.1 7.4 4.1 5.8 7.4 1.2 1 0 0 1 1 1 0 Macoilin family HAD PF12710.7 PXF42197.1 - 2.8e-20 73.5 0.3 5.7e-20 72.5 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF42197.1 - 7.7e-16 59.0 0.6 3e-15 57.1 0.6 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF42197.1 - 5.4e-12 46.0 0.0 1.9e-10 41.0 0.0 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PXF42197.1 - 7.8e-08 32.6 0.0 1.7e-06 28.3 0.1 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PXF42197.1 - 2e-05 24.1 0.0 0.00039 19.9 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase S6PP PF05116.13 PXF42197.1 - 3.8e-05 23.3 0.3 0.001 18.6 0.0 2.3 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_like PF13242.6 PXF42197.1 - 0.0023 17.9 0.2 0.1 12.7 0.0 2.8 1 1 2 3 3 3 1 HAD-hyrolase-like DUF705 PF05152.12 PXF42197.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF43 PF01861.16 PXF42197.1 - 0.035 13.3 0.2 0.07 12.3 0.0 1.5 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain NIF PF03031.18 PXF42197.1 - 0.17 11.7 0.0 0.61 9.8 0.0 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Glycolytic PF00274.19 PXF42198.1 - 4e-156 519.1 0.0 4.5e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I T3SS_ATPase_C PF18269.1 PXF42198.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain APH PF01636.23 PXF42199.1 - 1.6e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PXF42199.1 - 0.00069 19.3 0.0 0.00089 18.9 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PXF42199.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chromo PF00385.24 PXF42204.1 - 5.6e-07 29.4 0.8 1.2e-06 28.3 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNB PF00773.19 PXF42207.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 RNB domain OrsD PF12013.8 PXF42212.1 - 5.3e-07 30.1 1.4 1.6e-06 28.6 1.4 1.8 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 PXF42212.1 - 9.1e-05 22.7 2.0 0.35 11.2 1.8 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PXF42212.1 - 0.019 15.7 1.9 13 6.9 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF42212.1 - 0.03 14.8 1.4 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_10 PF13374.6 PXF42213.1 - 1.9e-27 94.3 22.2 0.00021 21.0 0.1 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42213.1 - 5.5e-27 91.8 1.8 0.06 13.4 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 PXF42213.1 - 4.7e-25 86.3 27.9 0.019 14.7 0.0 12.2 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42213.1 - 1.3e-24 86.3 6.0 0.042 14.1 0.0 8.2 5 3 3 8 8 8 6 Tetratricopeptide repeat Sel1 PF08238.12 PXF42213.1 - 5.7e-23 80.8 0.1 0.032 14.9 0.0 7.6 8 0 0 8 8 7 5 Sel1 repeat SNAP PF14938.6 PXF42213.1 - 1.8e-21 76.8 14.4 4.1e-06 26.4 0.1 4.2 1 1 4 5 5 5 5 Soluble NSF attachment protein, SNAP MIT PF04212.18 PXF42213.1 - 1.2e-20 73.4 4.6 0.031 14.4 0.0 8.1 8 0 0 8 8 8 5 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 PXF42213.1 - 4.8e-19 66.9 17.1 0.22 11.7 0.0 10.0 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42213.1 - 3.1e-18 64.4 18.7 0.098 12.9 0.1 9.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PXF42213.1 - 7.9e-10 38.7 1.9 17 6.6 0.0 7.0 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 PXF42213.1 - 2e-08 33.8 37.3 0.25 11.1 0.7 10.4 11 2 0 11 11 10 4 TPR repeat 14-3-3 PF00244.20 PXF42213.1 - 2.9e-08 33.5 3.0 1.6 8.2 0.0 5.6 3 2 1 5 5 5 2 14-3-3 protein DUF1722 PF08349.11 PXF42213.1 - 2.1e-05 24.7 0.1 0.89 9.9 0.0 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF1722) NSF PF02071.20 PXF42213.1 - 2.9e-05 24.0 21.3 25 6.3 0.1 7.9 8 0 0 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat LepB_GAP_N PF18172.1 PXF42213.1 - 0.00076 19.4 5.2 29 4.5 0.0 6.0 4 2 3 7 7 7 0 LepB GAP domain N-terminal subdomain DUF2225 PF09986.9 PXF42213.1 - 0.00078 19.2 8.2 0.73 9.5 0.1 4.3 1 1 2 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 PXF42213.1 - 0.0022 18.2 4.1 19 5.5 0.0 5.8 7 0 0 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Arfaptin PF06456.13 PXF42213.1 - 0.0055 16.3 0.0 44 3.5 0.0 4.2 1 1 3 5 5 5 0 Arfaptin-like domain Nup96 PF12110.8 PXF42213.1 - 0.011 14.9 6.4 12 4.9 0.0 5.7 1 1 6 7 7 7 0 Nuclear protein 96 DUF2542 PF10808.8 PXF42213.1 - 0.017 15.6 0.7 33 5.0 0.0 4.4 1 1 5 6 6 6 0 Protein of unknown function (DUF2542) Rep_2 PF01719.17 PXF42213.1 - 0.018 14.8 0.0 15 5.3 0.0 3.4 3 1 1 4 4 4 0 Plasmid replication protein Kelch_1 PF01344.25 PXF42213.1 - 0.047 13.3 5.1 20 4.8 0.0 5.2 6 0 0 6 6 6 0 Kelch motif SDH_C PF18317.1 PXF42213.1 - 0.073 12.9 4.0 98 2.8 0.0 4.6 5 0 0 5 5 5 0 Shikimate 5'-dehydrogenase C-terminal domain MIB_HERC2 PF06701.13 PXF42213.1 - 0.11 12.8 3.1 1.5 9.1 0.0 3.7 4 1 0 4 4 4 0 Mib_herc2 BB_PF PF18063.1 PXF42213.1 - 0.11 12.1 0.2 28 4.2 0.0 3.9 3 2 0 3 3 3 0 Beta barrel Pore-forming domain BAALC_N PF06989.12 PXF42213.1 - 0.21 11.9 13.6 33 4.9 0.1 5.4 5 0 0 5 5 5 0 BAALC N-terminus SapA PF02199.15 PXF42213.1 - 0.34 11.2 5.5 3.5e+02 1.6 0.0 5.8 6 0 0 6 6 6 0 Saposin A-type domain RPN6_C_helix PF18503.1 PXF42213.1 - 0.64 9.8 9.6 2.3e+02 1.7 0.0 6.4 7 0 0 7 7 7 0 26S proteasome subunit RPN6 C-terminal helix domain YtzH PF14165.6 PXF42213.1 - 0.72 10.3 3.8 42 4.6 0.0 4.2 5 0 0 5 5 5 0 YtzH-like protein Melibiase_C PF17801.1 PXF42213.1 - 3.4 7.8 7.5 23 5.2 0.1 4.2 4 1 0 4 4 4 0 Alpha galactosidase C-terminal beta sandwich domain TPR_10 PF13374.6 PXF42214.1 - 9.8e-17 60.2 12.1 0.001 18.8 0.1 4.5 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42214.1 - 8.1e-15 53.7 0.5 0.017 15.1 0.1 4.8 4 1 0 4 4 4 4 Tetratricopeptide repeat Sel1 PF08238.12 PXF42214.1 - 1.1e-14 54.6 0.0 0.012 16.2 0.0 4.1 4 0 0 4 4 4 4 Sel1 repeat TPR_1 PF00515.28 PXF42214.1 - 1.2e-14 53.4 13.3 0.0069 16.2 0.0 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42214.1 - 2.6e-12 46.9 1.1 0.043 14.1 0.2 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42214.1 - 1.6e-10 40.3 7.6 0.13 12.4 0.0 6.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42214.1 - 2.2e-10 39.9 6.9 0.065 13.5 0.1 5.7 7 0 0 7 7 6 3 Tetratricopeptide repeat MIT PF04212.18 PXF42214.1 - 4.8e-10 39.4 0.0 0.13 12.3 0.0 4.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain SNAP PF14938.6 PXF42214.1 - 5.5e-10 39.1 0.4 1.4e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP NSF PF02071.20 PXF42214.1 - 4.8e-05 23.3 4.1 9.4 7.5 0.1 4.5 4 0 0 4 4 4 1 Aromatic-di-Alanine (AdAR) repeat TPR_14 PF13428.6 PXF42214.1 - 9e-05 23.0 0.1 5.3 8.1 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat UPF0253 PF06786.12 PXF42214.1 - 0.0025 18.1 0.0 24 5.3 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0253) ANAPC3 PF12895.7 PXF42214.1 - 0.0052 17.0 0.3 5.2 7.4 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 14-3-3 PF00244.20 PXF42214.1 - 0.0054 16.3 0.3 3 7.3 0.0 3.1 1 1 2 3 3 3 1 14-3-3 protein Kelch_1 PF01344.25 PXF42214.1 - 0.0093 15.5 0.7 51 3.6 0.0 3.9 4 0 0 4 4 4 0 Kelch motif TPR_11 PF13414.6 PXF42214.1 - 0.063 13.0 21.3 0.34 10.6 0.8 6.2 7 1 0 7 7 7 0 TPR repeat Melibiase_C PF17801.1 PXF42214.1 - 0.11 12.6 0.1 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain RPN6_C_helix PF18503.1 PXF42214.1 - 0.54 10.0 3.7 92 2.9 0.0 4.1 4 0 0 4 4 4 0 26S proteasome subunit RPN6 C-terminal helix domain Sda PF08970.10 PXF42214.1 - 2.6 7.8 7.2 12 5.8 0.1 3.7 4 0 0 4 4 4 0 Sporulation inhibitor A TPR_1 PF00515.28 PXF42215.1 - 1.9e-29 100.2 18.9 0.0037 17.0 0.1 9.8 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42215.1 - 2.2e-27 93.0 0.7 0.0075 16.2 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 PXF42215.1 - 1.5e-25 88.3 19.5 7.4e-05 22.5 0.1 7.8 7 1 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42215.1 - 8.8e-25 86.8 3.3 0.0037 17.5 0.0 7.3 4 2 3 7 7 7 7 Tetratricopeptide repeat Sel1 PF08238.12 PXF42215.1 - 6.4e-23 80.7 0.0 0.086 13.6 0.0 7.1 7 0 0 7 7 7 6 Sel1 repeat TPR_8 PF13181.6 PXF42215.1 - 2.7e-21 73.9 19.1 0.04 14.1 0.1 8.1 9 0 0 9 9 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42215.1 - 6.1e-21 72.8 13.0 0.058 13.5 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat SNAP PF14938.6 PXF42215.1 - 5.5e-20 71.9 0.6 2.5e-07 30.4 0.2 3.6 1 1 3 4 4 4 4 Soluble NSF attachment protein, SNAP MIT PF04212.18 PXF42215.1 - 2.9e-18 65.7 0.2 0.083 13.0 0.0 7.0 7 0 0 7 7 7 5 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 PXF42215.1 - 3.8e-13 48.9 21.6 0.069 12.8 0.0 7.8 8 0 0 8 8 8 5 TPR repeat TPR_14 PF13428.6 PXF42215.1 - 2.5e-12 46.5 2.2 5.8 8.0 0.1 7.2 4 2 3 7 7 7 0 Tetratricopeptide repeat 14-3-3 PF00244.20 PXF42215.1 - 3.5e-09 36.5 0.1 3.2 7.2 0.0 5.3 1 1 4 6 6 6 2 14-3-3 protein DUF2225 PF09986.9 PXF42215.1 - 1.6e-08 34.5 0.3 0.021 14.6 0.0 3.3 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) SGTA_dimer PF16546.5 PXF42215.1 - 2.9e-08 33.4 0.0 19 5.1 0.0 6.8 4 1 3 7 7 7 0 Homodimerisation domain of SGTA UPF0253 PF06786.12 PXF42215.1 - 1.8e-07 31.3 0.0 6.8 7.0 0.0 6.7 7 0 0 7 7 7 0 Uncharacterised protein family (UPF0253) DUF4071 PF13281.6 PXF42215.1 - 5.9e-06 25.6 0.5 1.3 8.0 0.0 4.7 1 1 4 5 5 5 1 Domain of unknown function (DUF4071) NSF PF02071.20 PXF42215.1 - 0.0001 22.3 17.7 21 6.5 0.1 6.8 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 PXF42215.1 - 0.00019 22.0 0.0 28 5.5 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 PXF42215.1 - 0.00071 19.3 5.3 15 5.3 0.0 6.1 5 1 0 7 7 7 0 26S proteasome subunit RPN7 Kelch_1 PF01344.25 PXF42215.1 - 0.0019 17.7 7.7 1.7 8.3 0.0 5.3 7 0 0 7 7 6 1 Kelch motif TPR_MalT PF17874.1 PXF42215.1 - 0.0024 17.3 0.1 2.9 7.2 0.0 3.0 2 1 0 2 2 2 2 MalT-like TPR region Sda PF08970.10 PXF42215.1 - 0.0032 17.2 18.2 21 5.0 0.1 7.0 7 0 0 7 7 7 0 Sporulation inhibitor A SDH_C PF18317.1 PXF42215.1 - 0.0042 16.8 1.2 25 4.8 0.0 4.0 4 0 0 4 4 4 0 Shikimate 5'-dehydrogenase C-terminal domain BMC PF00936.19 PXF42215.1 - 0.009 16.0 0.0 6.9 6.7 0.0 3.8 2 1 2 4 4 4 0 BMC domain Rad52_Rad22 PF04098.15 PXF42215.1 - 0.014 15.4 4.1 39 4.1 0.0 5.3 4 1 2 7 7 7 0 Rad52/22 family double-strand break repair protein TTSSLRR PF12468.8 PXF42215.1 - 0.028 14.7 3.1 39 4.6 0.0 4.2 4 0 0 4 4 4 0 Type III secretion system leucine rich repeat protein MIB_HERC2 PF06701.13 PXF42215.1 - 0.028 14.7 2.8 28 5.1 0.0 4.6 3 2 2 5 5 5 0 Mib_herc2 RPN6_C_helix PF18503.1 PXF42215.1 - 0.033 13.9 0.7 1.8e+02 1.9 0.0 4.7 5 0 0 5 5 5 0 26S proteasome subunit RPN6 C-terminal helix domain DUF2542 PF10808.8 PXF42215.1 - 0.17 12.4 0.0 2 8.9 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2542) Vta1_C PF18097.1 PXF42215.1 - 0.34 10.7 5.0 46 3.8 0.0 5.1 7 0 0 7 7 7 0 Vta1 C-terminal domain LepB_GAP_N PF18172.1 PXF42215.1 - 0.5 10.2 1.5 89 2.9 0.0 3.8 5 0 0 5 5 5 0 LepB GAP domain N-terminal subdomain Ig_6 PF18452.1 PXF42215.1 - 8.3 6.1 6.0 23 4.7 0.0 4.0 6 0 0 6 6 5 0 Immunoglobulin domain CHAT PF12770.7 PXF42216.1 - 2.4e-23 83.0 0.0 2.9e-22 79.4 0.0 2.3 2 1 0 2 2 2 1 CHAT domain PspB PF06667.12 PXF42223.1 - 0.014 15.5 0.2 0.02 14.9 0.2 1.2 1 0 0 1 1 1 0 Phage shock protein B EcoEI_R_C PF08463.10 PXF42223.1 - 0.031 14.4 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal TERB2 PF15101.6 PXF42223.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 LANC_like PF05147.13 PXF42225.1 - 0.02 13.5 0.8 0.022 13.4 0.8 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF3292 PF11696.8 PXF42227.1 - 0.01 14.3 0.1 0.014 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) V_ATPase_I PF01496.19 PXF42227.1 - 2.9 5.7 6.2 0.69 7.8 3.5 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 PXF42229.1 - 0.2 11.9 2.2 0.38 11.0 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BRX_assoc PF16627.5 PXF42229.1 - 0.73 10.0 2.8 0.73 10.0 0.6 2.1 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain SecA_DEAD PF07517.14 PXF42230.1 - 2.2e-06 27.2 0.4 9.5e-05 21.8 0.1 2.2 1 1 1 2 2 2 2 SecA DEAD-like domain HSCB_C PF07743.13 PXF42233.1 - 0.028 14.9 2.0 0.085 13.4 0.5 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain TetR_C_8 PF14278.6 PXF42233.1 - 0.052 13.7 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region DUF1451 PF07295.11 PXF42233.1 - 0.1 12.6 1.7 0.19 11.8 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain Fib_alpha PF08702.10 PXF42233.1 - 2.3 8.4 6.5 4.6 7.4 4.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 PXF42233.1 - 2.7 8.6 5.6 16 6.1 5.6 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF1599 PF07659.11 PXF42234.1 - 0.028 14.8 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 Herpes_US12 PF05363.12 PXF42235.1 - 0.095 13.4 0.1 1.3 9.8 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus US12 family zf-CCHC_6 PF15288.6 PXF42236.1 - 0.011 15.6 1.6 0.028 14.3 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4755 PF15947.5 PXF42238.1 - 0.02 14.8 1.2 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4755) Carb_anhydrase PF00194.21 PXF42239.1 - 1.4e-32 113.3 0.1 1.8e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 PXF42239.1 - 0.11 12.5 0.4 2.3 8.1 0.2 2.3 2 0 0 2 2 2 0 Putative carbonic anhydrase GPDPase_memb PF10110.9 PXF42240.1 - 0.11 11.3 0.5 0.15 10.8 0.5 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase IL11 PF07400.11 PXF42241.1 - 0.073 12.7 0.1 0.084 12.5 0.1 1.1 1 0 0 1 1 1 0 Interleukin 11 AdoHcyase_NAD PF00670.21 PXF42242.1 - 1.2e-48 165.3 1.1 1.5e-48 164.9 1.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 PXF42242.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 PXF42242.1 - 0.0069 15.8 0.3 0.012 15.0 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF42242.1 - 0.034 14.2 0.1 0.079 13.0 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MCR_C PF04609.12 PXF42242.1 - 0.072 12.2 0.2 0.097 11.7 0.2 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C RXLR_WY PF18634.1 PXF42242.1 - 0.081 12.9 0.1 0.58 10.1 0.0 2.2 2 1 1 3 3 3 0 RXLR phytopathogen effector protein WY-domain OsmC PF02566.19 PXF42242.1 - 0.11 13.0 0.0 0.69 10.4 0.0 2.1 1 1 2 3 3 3 0 OsmC-like protein Urocanase PF01175.18 PXF42242.1 - 0.2 11.3 0.3 0.26 10.9 0.3 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain NTP_transferase PF00483.23 PXF42245.1 - 3.1e-17 63.0 0.0 1.4e-16 60.8 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyl transferase GHMP_kinases_N PF00288.26 PXF42245.1 - 3e-11 43.4 0.4 1.2e-10 41.5 0.1 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain NTP_transf_3 PF12804.7 PXF42245.1 - 2.2e-05 24.8 0.0 6.4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 MobA-like NTP transferase domain GalKase_gal_bdg PF10509.9 PXF42245.1 - 0.041 13.5 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Fucokinase PF07959.12 PXF42245.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase MTS_N PF08468.11 PXF42245.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Abhydrolase_6 PF12697.7 PXF42246.1 - 6.9e-15 56.2 9.0 6.9e-15 56.2 9.0 1.9 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF42246.1 - 2.9e-11 43.5 0.6 5.5e-11 42.6 0.6 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF42246.1 - 3.2e-09 36.4 2.0 1.9e-08 33.9 1.9 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 PXF42246.1 - 0.00021 21.2 0.1 0.00062 19.7 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase DLH PF01738.18 PXF42246.1 - 0.00073 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Ndr PF03096.14 PXF42246.1 - 0.051 12.3 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Ndr family NAD_binding_8 PF13450.6 PXF42247.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PXF42247.1 - 0.063 12.5 0.2 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain Pirin PF02678.16 PXF42247.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Pirin Myc_N PF01056.18 PXF42248.1 - 0.0033 17.4 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF2613 PF11021.8 PXF42248.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2613) NUDIX_2 PF13869.6 PXF42249.1 - 4.4e-59 199.2 0.0 5.2e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 PXF42249.1 - 6.7e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain VIR_N PF15912.5 PXF42249.1 - 0.16 11.6 0.7 0.24 11.0 0.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 PXF42249.1 - 0.34 10.9 2.6 0.61 10.1 2.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PXF42249.1 - 0.59 9.6 2.9 0.84 9.1 2.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HD_4 PF13328.6 PXF42250.1 - 4.3e-44 150.0 4.5 1.7e-23 83.1 0.6 2.5 2 0 0 2 2 2 2 HD domain RelA_SpoT PF04607.17 PXF42250.1 - 3e-24 85.5 0.0 1.2e-23 83.6 0.0 2.1 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 PXF42250.1 - 1.4e-21 76.2 0.1 3.5e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 TGS domain HD PF01966.22 PXF42250.1 - 3.6e-09 36.9 0.3 2.4e-08 34.2 0.3 2.4 1 1 0 1 1 1 1 HD domain ACT_4 PF13291.6 PXF42250.1 - 3.9e-08 33.8 0.0 9.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain RXLR PF16810.5 PXF42251.1 - 0.048 14.1 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity ADH_zinc_N_2 PF13602.6 PXF42253.1 - 1.2e-11 45.8 0.0 2.4e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PXF42253.1 - 9.2e-11 41.6 0.0 2.9e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF42253.1 - 2.2e-08 34.2 0.0 2e-07 31.1 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Rossmann-like PF10727.9 PXF42253.1 - 0.0099 15.7 1.8 0.27 11.1 0.0 3.0 1 1 1 3 3 3 1 Rossmann-like domain Semialdhyde_dh PF01118.24 PXF42253.1 - 0.035 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PXF42253.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 PXF42253.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 PXF42253.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 PXF42253.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2301 PF10063.9 PXF42254.1 - 4.4e-43 147.0 2.3 4.4e-43 147.0 2.3 1.6 2 0 0 2 2 2 1 Uncharacterized integral membrane protein (DUF2301) Mpv17_PMP22 PF04117.12 PXF42255.1 - 7.6e-23 80.5 0.2 1.3e-22 79.7 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BTB PF00651.31 PXF42256.1 - 2.7e-14 53.3 0.3 6.5e-14 52.1 0.3 1.6 1 1 0 1 1 1 1 BTB/POZ domain DUF3929 PF13066.6 PXF42256.1 - 0.069 13.2 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) IL17 PF06083.11 PXF42256.1 - 0.098 13.1 0.5 0.21 12.1 0.1 1.7 2 0 0 2 2 2 0 Interleukin-17 ANAPC4_WD40 PF12894.7 PXF42257.1 - 0.023 15.0 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3704 PF12488.8 PXF42257.1 - 0.05 13.3 0.3 0.05 13.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) GreA_GreB PF01272.19 PXF42257.1 - 0.14 12.0 0.2 0.36 10.7 0.2 1.6 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term Cyclin_N PF00134.23 PXF42258.1 - 1.6e-11 44.1 0.5 1.6e-11 44.1 0.5 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Atthog PF18800.1 PXF42258.1 - 0.0064 16.4 1.7 0.0071 16.2 0.3 1.8 2 0 0 2 2 2 1 Attenuator of Hedgehog UvrC_HhH_N PF08459.11 PXF42259.1 - 4e-41 140.5 0.0 5.5e-40 136.8 0.0 2.2 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 PXF42259.1 - 1.3e-10 41.7 0.0 3.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 PXF42259.1 - 3.4e-07 29.8 0.0 8.3e-06 25.4 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 PXF42259.1 - 7e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif UVR PF02151.19 PXF42259.1 - 2.1e-05 24.1 1.6 5.9e-05 22.7 1.6 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif GIY-YIG PF01541.24 PXF42259.1 - 0.00017 21.8 0.0 0.0011 19.2 0.0 2.3 1 1 0 1 1 1 1 GIY-YIG catalytic domain HHH_3 PF12836.7 PXF42259.1 - 0.0075 16.5 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4096 PF13340.6 PXF42259.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Glyco_transf_8 PF01501.20 PXF42262.1 - 1.4e-06 28.1 0.1 0.0028 17.2 0.0 2.7 3 1 0 3 3 3 2 Glycosyl transferase family 8 DUF3094 PF11293.8 PXF42262.1 - 0.13 12.0 0.4 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Peptidase_C26 PF07722.13 PXF42264.1 - 6e-42 143.8 0.4 2.4e-41 141.8 0.4 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 PXF42264.1 - 2.2e-09 37.4 0.2 3.8e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 PXF42264.1 - 0.043 13.6 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 DJ-1/PfpI family DUF547 PF04784.14 PXF42265.1 - 9.3e-38 129.0 0.0 1.8e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Pkinase PF00069.25 PXF42266.1 - 9e-68 228.5 0.0 1.2e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42266.1 - 4e-30 105.0 0.0 7.5e-30 104.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF42266.1 - 0.0002 20.8 0.1 0.00051 19.5 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF42266.1 - 0.00066 18.7 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PXF42266.1 - 0.0054 16.7 0.0 0.036 14.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF42266.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mitofilin PF09731.9 PXF42267.1 - 3.6e-27 95.5 30.1 2.6e-26 92.7 30.1 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein V_ATPase_I PF01496.19 PXF42267.1 - 6.5 4.5 5.7 11 3.8 5.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rpr2 PF04032.16 PXF42268.1 - 9.9e-13 48.2 1.8 1.9e-12 47.3 1.8 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mu-like_Com PF10122.9 PXF42268.1 - 0.0014 18.0 0.4 0.0014 18.0 0.4 2.2 2 0 0 2 2 2 1 Mu-like prophage protein Com WD40_like PF17005.5 PXF42269.1 - 0.05 12.9 1.7 2.1 7.6 0.4 2.9 1 1 2 3 3 3 0 WD40-like domain Zwilch PF09817.9 PXF42270.1 - 0.17 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch zf-H2C2_2 PF13465.6 PXF42271.1 - 3.6e-11 43.0 37.0 2.3e-07 30.9 1.4 5.5 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 PXF42271.1 - 7.8e-11 41.8 43.8 0.00057 20.2 3.2 5.6 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42271.1 - 8.4e-09 35.5 40.9 0.0037 18.0 2.9 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 PXF42271.1 - 1.3e-05 25.4 23.7 0.0061 16.9 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 PXF42271.1 - 0.0092 15.7 14.2 0.11 12.3 1.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 PXF42271.1 - 0.0094 16.2 16.2 0.88 9.9 0.2 4.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PXF42271.1 - 0.012 16.3 14.6 0.51 11.0 0.1 4.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 PXF42271.1 - 0.018 15.0 0.7 0.018 15.0 0.7 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger PyrI_C PF02748.15 PXF42271.1 - 2.4 8.1 9.2 0.75 9.7 0.2 3.6 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Vps36-NZF-N PF16988.5 PXF42271.1 - 4.7 6.7 9.1 0.5 9.8 0.2 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_2 PF12756.7 PXF42271.1 - 6.2 7.2 17.7 93 3.4 0.4 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PXF42271.1 - 9.2 6.5 16.6 1.8 8.7 0.5 4.0 3 2 1 4 4 4 0 Zinc ribbon domain Ufd2P_core PF10408.9 PXF42272.1 - 1e-170 569.4 0.0 6.4e-170 566.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 PXF42272.1 - 2.6e-25 88.4 0.4 6.5e-25 87.1 0.4 1.7 1 0 0 1 1 1 1 U-box domain Ribosomal_L3 PF00297.22 PXF42273.1 - 1.5e-179 596.8 8.0 1.7e-179 596.5 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PET PF06297.14 PXF42274.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 PET Domain Peptidase_C48 PF02902.19 PXF42275.1 - 2.3e-10 40.7 0.0 4.1e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CRAL_TRIO PF00650.20 PXF42276.1 - 1.7e-14 53.9 0.0 2.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PXF42276.1 - 0.00035 20.7 0.1 0.00063 19.9 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 PXF42277.1 - 7.9e-20 71.2 0.0 2.3e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PXF42277.1 - 0.0038 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RPN6_N PF18055.1 PXF42278.1 - 4e-32 111.0 1.4 4e-32 111.0 1.4 2.9 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 PXF42278.1 - 8.9e-20 71.2 0.3 8.9e-20 71.2 0.3 2.5 4 0 0 4 4 4 1 PCI domain RPN6_C_helix PF18503.1 PXF42278.1 - 2.1e-07 30.6 0.3 4.6e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 PXF42278.1 - 0.0012 18.3 4.9 0.0021 17.5 4.9 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 PXF42278.1 - 0.011 16.0 2.5 0.011 16.0 2.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DDRGK PF09756.9 PXF42278.1 - 0.026 14.1 0.2 0.047 13.3 0.2 1.4 1 0 0 1 1 1 0 DDRGK domain TPR_19 PF14559.6 PXF42278.1 - 0.061 13.8 5.6 0.86 10.2 0.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Laminin_II PF06009.12 PXF42278.1 - 0.066 13.2 3.7 0.055 13.5 0.9 2.3 2 0 0 2 2 2 0 Laminin Domain II DNA_pol3_a_NII PF11490.8 PXF42278.1 - 1.1 9.2 3.7 0.61 10.0 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TPR_16 PF13432.6 PXF42278.1 - 2.8 8.7 7.1 1.6 9.5 0.4 3.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Nramp PF01566.18 PXF42279.1 - 1.5e-131 438.6 16.6 1.5e-131 438.6 16.6 1.8 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein DNA_pol_E_B PF04042.16 PXF42280.1 - 1.3e-38 132.4 0.1 2.2e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Hist_deacetyl PF00850.19 PXF42281.1 - 3.1e-86 289.6 0.0 3.8e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Peripla_BP_7 PF18610.1 PXF42281.1 - 0.088 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain RNase_PH PF01138.21 PXF42282.1 - 1.3e-19 71.0 0.6 8.7e-19 68.3 0.2 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF42282.1 - 4.7e-07 29.7 0.1 2.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Glyco_transf_25 PF01755.17 PXF42283.1 - 3.9e-15 56.2 0.0 4.7e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Uma2 PF05685.12 PXF42284.1 - 4.4e-27 94.7 0.0 5.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease S4 PF01479.25 PXF42285.1 - 0.00012 21.7 0.1 0.0003 20.4 0.1 1.7 1 0 0 1 1 1 1 S4 domain RNA_pol_Rpb1_5 PF04998.17 PXF42286.1 - 1.9e-79 266.8 0.0 4.2e-79 265.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PXF42286.1 - 2.3e-59 200.4 0.0 1e-58 198.2 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PXF42286.1 - 1.7e-31 109.3 0.0 3.1e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 PXF42286.1 - 1.1e-18 67.7 0.0 3.2e-17 62.8 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 PXF42286.1 - 1.4e-17 63.5 0.0 5.4e-17 61.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 WD40 PF00400.32 PXF42287.1 - 7.8e-28 96.2 6.9 0.0003 21.5 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42287.1 - 1.2e-05 25.5 0.0 3.7 7.9 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PXF42287.1 - 0.072 11.6 0.0 0.66 8.4 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain BTK PF00779.19 PXF42287.1 - 0.075 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 BTK motif EamA PF00892.20 PXF42288.1 - 1.6e-14 54.2 3.8 2.1e-14 53.9 3.8 1.1 1 0 0 1 1 1 1 EamA-like transporter family NOZZLE PF08744.10 PXF42288.1 - 0.1 12.0 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE Sulfotransfer_2 PF03567.14 PXF42290.1 - 1.5e-27 97.2 0.1 2e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family NDUF_B4 PF07225.12 PXF42290.1 - 0.056 13.3 0.4 20 5.1 0.1 3.0 2 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Epimerase PF01370.21 PXF42291.1 - 1.5e-17 63.9 0.0 6.7e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF42291.1 - 3.1e-16 59.2 0.0 2.7e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF42291.1 - 2.2e-11 44.0 0.5 5.8e-11 42.6 0.5 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PXF42291.1 - 1.4e-10 40.8 0.0 1.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 PXF42291.1 - 1.6e-08 34.0 0.0 0.00019 20.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein KR PF08659.10 PXF42291.1 - 1.7e-07 31.3 0.1 8e-07 29.1 0.0 1.8 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 PXF42291.1 - 2.1e-06 28.0 0.0 4.7e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 PXF42291.1 - 4.3e-06 26.5 0.1 2.8e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 PXF42291.1 - 0.00027 20.2 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PXF42291.1 - 0.00051 19.5 0.0 0.04 13.3 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 PXF42291.1 - 0.0035 16.8 0.0 0.0059 16.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 PXF42291.1 - 0.0037 17.7 0.0 0.0086 16.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain LAB_N PF07578.11 PXF42291.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Peptidase_M16_M PF16187.5 PXF42292.1 - 3.6e-85 285.7 0.0 5.2e-85 285.1 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PXF42292.1 - 6e-40 136.6 0.1 3.7e-39 134.1 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PXF42292.1 - 6.7e-28 97.9 0.0 5.1e-15 55.9 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Mei5_like PF17021.5 PXF42292.1 - 0.037 14.1 0.1 0.091 12.8 0.1 1.6 1 0 0 1 1 1 0 Putative double-strand recombination repair-like Actin PF00022.19 PXF42293.1 - 4.1e-16 58.6 1.3 1.2e-08 34.0 0.1 3.7 3 1 0 3 3 3 2 Actin Actin_micro PF17003.5 PXF42293.1 - 1.8e-05 24.1 0.0 0.0055 15.9 0.0 2.4 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 PXF42293.1 - 0.037 14.5 0.5 0.14 12.6 0.2 2.4 2 1 0 2 2 2 0 Cell division protein FtsA Peptidase_A2B PF12384.8 PXF42293.1 - 0.093 12.3 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Ty3 transposon peptidase PilM_2 PF11104.8 PXF42293.1 - 0.13 11.2 0.4 11 4.9 0.0 2.7 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; Pkinase PF00069.25 PXF42296.1 - 3.8e-50 170.7 0.0 4.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42296.1 - 7.9e-24 84.3 0.1 1.6e-23 83.3 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF42296.1 - 3.1e-05 23.1 0.5 6.7e-05 22.0 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF42296.1 - 5.2e-05 22.7 0.2 8.6e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 PXF42296.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 PXF42296.1 - 0.033 13.5 0.2 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 PXF42296.1 - 0.089 12.7 1.1 0.29 11.0 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family APS_kinase PF01583.20 PXF42298.1 - 2.2e-71 238.9 0.0 2.7e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 PXF42298.1 - 1.1e-07 32.1 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PXF42298.1 - 8.7e-05 23.1 0.1 0.00016 22.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 PXF42298.1 - 0.00036 20.1 0.0 0.00089 18.8 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 PXF42298.1 - 0.0015 19.1 0.0 0.0026 18.3 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PXF42298.1 - 0.0051 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CbiA PF01656.23 PXF42298.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 PXF42298.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ParA PF10609.9 PXF42298.1 - 0.057 12.8 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 PXF42298.1 - 0.091 13.1 0.1 0.15 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain SelB-wing_2 PF09106.11 PXF42298.1 - 0.097 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix CPT PF07931.12 PXF42298.1 - 0.13 12.1 0.7 1.4 8.7 0.7 2.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.17 PXF42298.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Gly-zipper_OmpA PF13436.6 PXF42298.1 - 0.2 11.5 3.9 0.34 10.7 3.9 1.4 1 0 0 1 1 1 0 Glycine-zipper domain PMT_4TMC PF16192.5 PXF42299.1 - 6.6e-38 130.3 8.6 6.6e-38 130.3 8.6 2.2 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 PXF42299.1 - 1.1e-33 116.9 15.9 1.1e-33 116.9 15.9 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_1 PF00515.28 PXF42301.1 - 1e-55 183.4 16.1 6.2e-06 25.8 0.1 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42301.1 - 2.1e-47 155.4 17.5 0.00013 21.8 0.2 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42301.1 - 4.5e-37 123.2 10.3 0.00035 20.5 0.1 10.3 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 PXF42301.1 - 4.4e-27 92.5 21.0 0.014 16.2 0.2 10.8 3 2 8 11 11 11 10 Tetratricopeptide repeat TPR_9 PF13371.6 PXF42301.1 - 2e-21 75.9 13.8 1e-06 28.8 0.1 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 PXF42301.1 - 2.6e-20 71.3 18.4 0.00067 19.9 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 PXF42301.1 - 6e-20 71.5 19.2 0.00019 21.8 0.3 7.5 4 1 3 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 PXF42301.1 - 8.1e-20 71.2 20.7 4.2e-07 30.5 0.4 7.0 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42301.1 - 1.8e-19 69.8 23.1 2.8e-05 24.3 2.5 7.6 3 3 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 PXF42301.1 - 8.9e-19 66.9 25.2 0.0014 18.3 0.3 10.5 7 2 4 11 11 11 6 TPR repeat TPR_7 PF13176.6 PXF42301.1 - 1.6e-18 65.3 7.6 0.037 14.1 0.6 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 PXF42301.1 - 9.1e-18 63.6 15.5 0.69 10.7 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF42301.1 - 9.8e-09 35.3 9.9 0.022 15.0 1.4 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PXF42301.1 - 7.3e-08 32.0 11.9 0.15 11.3 0.1 5.4 1 1 2 5 5 5 3 Tetratricopeptide repeat ChAPs PF09295.10 PXF42301.1 - 8.5e-07 28.3 2.5 0.016 14.3 0.0 2.9 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 PXF42301.1 - 0.00023 21.5 6.0 2.1 8.7 0.2 5.1 3 2 2 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 PXF42301.1 - 0.00036 21.0 13.9 0.01 16.3 1.0 3.9 4 0 0 4 4 4 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 PXF42301.1 - 0.0064 16.3 14.8 1.8 8.6 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PXF42301.1 - 0.038 13.6 0.2 3.6 7.3 0.3 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Rapsyn_N PF10579.9 PXF42301.1 - 0.076 13.1 0.2 10 6.3 0.0 3.5 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region DUF3209 PF11483.8 PXF42301.1 - 0.16 12.5 0.9 1.2 9.6 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF3209) EST1_DNA_bind PF10373.9 PXF42301.1 - 0.63 9.5 2.0 4.6 6.6 0.2 2.7 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain TPR_21 PF09976.9 PXF42301.1 - 1.9 8.1 9.7 12 5.6 0.2 4.1 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain DUF1965 PF09248.10 PXF42301.1 - 2.5 7.9 4.0 28 4.6 0.2 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1965) Rieske PF00355.26 PXF42302.1 - 2.7e-15 56.1 0.0 6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PXF42302.1 - 8.9e-10 38.6 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase USP7_C2 PF14533.6 PXF42303.1 - 0.069 12.9 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF3449 PF11931.8 PXF42304.1 - 6.9e-62 208.5 0.0 1.5e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 PXF42304.1 - 1.6e-18 67.0 0.3 3.4e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Telomere_Sde2_2 PF13297.6 PXF42304.1 - 3.9e-10 39.2 1.4 1e-09 37.9 1.4 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.8 PXF42304.1 - 0.0031 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain MAP65_ASE1 PF03999.12 PXF42304.1 - 0.035 12.8 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.11 PXF42304.1 - 0.062 13.6 0.0 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) POTRA_TamA_1 PF17243.2 PXF42304.1 - 0.11 12.6 3.3 18 5.5 0.1 3.9 3 0 0 3 3 3 0 POTRA domain TamA domain 1 FtsK_gamma PF09397.10 PXF42304.1 - 0.12 12.2 0.2 6.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Ftsk gamma domain DUF2175 PF09943.9 PXF42304.1 - 0.2 12.0 2.0 21 5.5 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2_4 PF13894.6 PXF42304.1 - 0.25 12.3 0.7 0.81 10.7 0.1 2.3 2 0 0 2 2 1 0 C2H2-type zinc finger LPD22 PF18834.1 PXF42304.1 - 1.2 9.4 5.5 0.4 10.9 0.3 2.8 3 0 0 3 3 3 0 Large polyvalent protein associated domain 22 P4Ha_N PF08336.11 PXF42304.1 - 5.3 7.1 6.9 2.4 8.2 0.2 3.1 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region APG6_N PF17675.1 PXF42304.1 - 6.2 7.4 13.4 0.3 11.6 1.3 3.6 3 1 1 4 4 4 0 Apg6 coiled-coil region GDI PF00996.18 PXF42305.1 - 2.6e-188 625.9 0.0 3.2e-188 625.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad51 PF08423.11 PXF42306.1 - 8.3e-11 41.6 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 PXF42306.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein RabGAP-TBC PF00566.18 PXF42307.1 - 5.2e-48 163.5 0.0 1.1e-47 162.5 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Asparaginase_2 PF01112.18 PXF42308.1 - 7.4e-78 261.7 1.8 4e-77 259.2 1.8 1.8 1 1 0 1 1 1 1 Asparaginase zf-C2H2 PF00096.26 PXF42309.1 - 2.3 8.8 7.7 1.7 9.2 4.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Bromo_TP PF07524.13 PXF42310.1 - 0.00039 20.4 0.1 0.00099 19.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Phage_GPO PF05929.11 PXF42310.1 - 0.031 13.9 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fer4_13 PF13370.6 PXF42311.1 - 5.5e-16 58.8 0.4 1.2e-15 57.8 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Lactamase_B PF00753.27 PXF42311.1 - 0.037 14.0 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glyco_hydro_49N PF17433.2 PXF42311.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain AAA_31 PF13614.6 PXF42313.1 - 0.046 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PXF42314.1 - 1.2e-34 117.8 26.6 3.7e-08 33.9 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42314.1 - 3.7e-10 40.0 2.0 0.068 13.5 0.0 5.3 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF42314.1 - 0.0027 16.8 0.1 2.4 7.0 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 PXF42314.1 - 0.012 15.5 0.1 3.2 7.7 0.0 3.0 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Metallophos PF00149.28 PXF42315.1 - 2.3e-19 70.7 0.0 2.8e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sec63 PF02889.16 PXF42316.1 - 3.3e-136 452.5 0.0 4.3e-76 255.5 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PXF42316.1 - 1.1e-34 119.8 0.3 7e-29 100.8 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 PXF42316.1 - 1e-30 106.2 1.8 4.7e-30 104.0 1.8 2.3 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 PXF42316.1 - 2.9e-15 56.7 0.0 3e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PXF42316.1 - 5e-12 46.1 0.4 3.6e-08 33.7 0.0 4.2 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PXF42316.1 - 0.0027 18.0 0.7 0.33 11.2 0.0 3.6 3 1 0 3 3 3 1 AAA domain zf-U1 PF06220.12 PXF42317.1 - 6e-06 25.9 0.1 9.4e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger CDC27 PF09507.10 PXF42317.1 - 2.5 7.4 17.8 3 7.1 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S24 PF00717.23 PXF42318.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ras PF00071.22 PXF42319.1 - 6.1e-38 130.0 0.0 8.2e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF42319.1 - 5.3e-09 36.3 0.0 8.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PXF42319.1 - 3.8e-05 23.3 0.0 5.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PXF42319.1 - 9.2e-05 22.0 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Oxidored_nitro PF00148.19 PXF42319.1 - 0.087 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase COX17 PF05051.13 PXF42321.1 - 0.0034 17.7 2.3 0.0064 16.8 2.3 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 PXF42321.1 - 0.063 13.5 3.9 0.28 11.5 3.9 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Ndufs5 PF10200.9 PXF42321.1 - 0.082 13.2 5.0 0.059 13.6 3.4 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 PXF42321.1 - 0.083 13.0 4.3 0.14 12.3 4.3 1.4 1 0 0 1 1 1 0 CHCH domain UCR_hinge PF02320.16 PXF42321.1 - 0.63 10.3 6.2 1.9 8.7 1.3 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Acetyltransf_13 PF13880.6 PXF42322.1 - 6.1e-22 77.4 0.0 1.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 PXF42322.1 - 3e-08 33.3 0.1 5.2e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 PXF42322.1 - 0.031 14.7 0.3 0.062 13.7 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF42322.1 - 0.046 14.0 0.4 0.26 11.6 0.3 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family CxC5 PF18718.1 PXF42322.1 - 0.15 12.1 0.4 11 6.2 0.1 2.3 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases zf-MYND PF01753.18 PXF42323.1 - 2.3e-08 34.0 17.5 3.9e-08 33.2 17.5 1.4 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.6 PXF42323.1 - 0.21 11.0 3.1 0.43 10.1 3.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PolC_DP2 PF03833.13 PXF42323.1 - 0.63 7.8 4.8 0.91 7.3 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Lactonase PF10282.9 PXF42324.1 - 3e-41 141.8 0.0 4.2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller tRNA-synt_1g PF09334.11 PXF42327.1 - 3.1e-150 500.3 0.0 4.1e-150 499.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 PXF42327.1 - 6.1e-26 90.4 2.3 1.2e-25 89.5 2.3 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 PXF42327.1 - 5.3e-08 31.6 0.0 0.00015 20.2 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PXF42327.1 - 0.00018 21.0 0.0 0.0017 17.8 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 PXF42327.1 - 0.01 15.8 5.1 0.021 14.8 5.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 PXF42327.1 - 2.7 7.5 9.6 6.5 6.3 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.13 PXF42327.1 - 3.5 7.7 5.0 0.78 9.8 0.4 2.0 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type HypA PF01155.19 PXF42327.1 - 5.1 7.2 7.0 8.1 6.5 0.5 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GTP_EFTU PF00009.27 PXF42328.1 - 4.4e-23 81.8 0.1 7.4e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PXF42328.1 - 1.2e-06 28.8 0.1 4.6e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PXF42328.1 - 2.5e-05 24.6 0.9 7.7e-05 23.0 0.9 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF42328.1 - 0.0032 17.5 0.1 0.0083 16.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF42328.1 - 0.0075 16.2 1.8 2.2 8.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PXF42328.1 - 0.052 13.1 0.2 1 8.9 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ImcF-related_N PF14331.6 PXF42328.1 - 0.066 12.6 0.1 0.14 11.4 0.1 1.5 1 0 0 1 1 1 0 ImcF-related N-terminal domain PduV-EutP PF10662.9 PXF42328.1 - 0.068 12.9 0.1 16 5.2 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PXF42328.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DNA_pol_A PF00476.20 PXF42329.1 - 7.6e-78 262.2 1.4 3.6e-76 256.6 0.1 2.9 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 PXF42329.1 - 7.7e-23 81.1 0.0 1.5e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PPP5 PF08321.12 PXF42329.1 - 0.076 13.3 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 PPP5 TPR repeat region Retrotrans_gag PF03732.17 PXF42330.1 - 6.6e-05 23.1 0.0 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein DUF755 PF05501.11 PXF42330.1 - 0.005 17.1 1.6 0.007 16.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF755) Snapin_Pallidin PF14712.6 PXF42330.1 - 0.014 15.8 2.3 0.055 13.9 2.3 2.0 1 1 0 1 1 1 0 Snapin/Pallidin SPACA9 PF15120.6 PXF42330.1 - 0.2 11.4 1.7 0.43 10.3 1.7 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 SR-25 PF10500.9 PXF42330.1 - 0.21 11.2 8.9 0.38 10.3 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF16 PF01519.16 PXF42330.1 - 0.32 11.5 1.3 0.65 10.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 PXF42330.1 - 0.85 10.1 3.6 0.68 10.4 0.7 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-CCHC_2 PF13696.6 PXF42330.1 - 3 7.8 8.4 0.086 12.7 2.2 1.6 2 0 0 2 2 2 0 Zinc knuckle SIS_2 PF13580.6 PXF42331.1 - 0.41 10.7 2.2 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 SIS domain Ribosomal_L7Ae PF01248.26 PXF42332.1 - 2.5e-21 75.2 0.2 5.4e-21 74.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family COQ7 PF03232.13 PXF42333.1 - 3e-71 238.7 0.8 3.6e-71 238.5 0.8 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 PXF42333.1 - 1.3e-06 28.9 0.5 3.9e-06 27.3 0.4 1.8 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 PXF42333.1 - 0.003 17.8 0.6 0.057 13.6 0.2 2.2 1 1 1 2 2 2 2 Ferritin-like domain DUF4439 PF14530.6 PXF42333.1 - 0.056 14.1 0.3 0.11 13.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) HEAT_2 PF13646.6 PXF42334.1 - 2.9e-44 149.4 39.8 4.5e-10 39.8 2.0 6.8 3 2 5 8 8 8 7 HEAT repeats HEAT PF02985.22 PXF42334.1 - 3.6e-23 79.6 13.2 0.025 14.8 0.0 9.8 9 0 0 9 9 9 6 HEAT repeat HEAT_PBS PF03130.16 PXF42334.1 - 1.3e-13 50.2 13.9 0.56 11.0 0.0 9.7 9 0 0 9 9 9 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 PXF42334.1 - 0.00015 22.2 21.3 1.3 9.6 0.3 9.1 7 3 3 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 PXF42334.1 - 0.00042 20.4 0.2 0.088 12.8 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PXF42334.1 - 0.00048 20.1 7.3 2.4 8.4 0.1 5.9 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PXF42334.1 - 0.0019 16.8 2.3 0.016 13.8 0.7 2.9 3 1 0 3 3 3 1 Adaptin N terminal region Vitellogenin_N PF01347.22 PXF42334.1 - 0.071 11.5 0.1 9.1 4.5 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein amino terminal region RICTOR_V PF14668.6 PXF42334.1 - 0.13 12.5 0.0 3.9 7.8 0.0 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Cohesin_HEAT PF12765.7 PXF42334.1 - 1.2 9.5 4.8 3.6 8.0 0.2 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Molybdopterin PF00384.22 PXF42335.1 - 9.1e-49 166.6 0.0 2.1e-47 162.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 PXF42335.1 - 2.8e-15 56.7 0.1 7.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Glutaminase PF04960.15 PXF42336.1 - 6.5e-89 297.9 0.0 1.9e-88 296.4 0.0 1.8 2 1 0 2 2 2 1 Glutaminase EF-hand_14 PF17959.1 PXF42336.1 - 0.00015 22.1 0.8 0.00048 20.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain TerB PF05099.13 PXF42336.1 - 0.00015 21.8 0.2 0.00029 20.8 0.2 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB Peptidase_S8 PF00082.22 PXF42338.1 - 6.8e-23 81.4 9.6 5.1e-22 78.5 9.6 1.9 1 1 0 1 1 1 1 Subtilase family DDE_1 PF03184.19 PXF42340.1 - 0.0032 17.1 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SHOCT PF09851.9 PXF42341.1 - 0.039 13.7 0.3 0.088 12.6 0.3 1.7 1 0 0 1 1 1 0 Short C-terminal domain PseudoU_synth_2 PF00849.22 PXF42342.1 - 0.023 14.8 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase zf-C2H2 PF00096.26 PXF42343.1 - 1e-15 57.2 40.4 9e-05 22.7 1.2 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42343.1 - 3.1e-14 52.5 43.9 0.0013 19.4 3.6 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF42343.1 - 1.8e-09 37.6 32.0 0.00078 19.7 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PXF42343.1 - 2.7e-09 37.0 32.2 0.0045 17.4 0.4 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 PXF42343.1 - 7.9e-09 35.3 32.4 0.0014 18.6 2.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 PXF42343.1 - 1.9e-07 31.2 27.2 0.0097 16.3 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 PXF42343.1 - 2.6e-07 30.4 28.6 0.024 14.5 0.0 6.0 6 1 0 6 6 6 4 zinc-finger of a C2HC-type zf-Di19 PF05605.12 PXF42343.1 - 7.1e-05 23.0 1.2 7.1e-05 23.0 1.2 3.4 3 1 0 3 3 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PXF42343.1 - 0.00093 18.9 25.2 0.014 15.2 0.5 4.8 5 0 0 5 5 5 3 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 PXF42343.1 - 0.005 16.9 23.5 0.28 11.3 0.7 4.5 3 1 1 4 4 4 2 Zinc ribbon domain zf-C2H2_3rep PF18868.1 PXF42343.1 - 0.0098 16.6 5.1 0.0098 16.6 5.1 2.5 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats Rubredoxin PF00301.20 PXF42343.1 - 0.017 15.2 0.3 0.017 15.2 0.3 3.8 4 0 0 4 4 4 0 Rubredoxin zf-C2H2_12 PF18658.1 PXF42343.1 - 0.043 13.4 0.4 0.24 11.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type ADK_lid PF05191.14 PXF42343.1 - 0.056 13.4 17.5 1.3 9.1 0.1 4.1 3 2 0 3 3 3 0 Adenylate kinase, active site lid zf_C2H2_ZHX PF18387.1 PXF42343.1 - 0.089 12.4 0.0 0.089 12.4 0.0 3.1 3 1 1 4 4 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 PXF42343.1 - 0.11 12.5 17.0 0.27 11.3 1.2 4.3 3 1 0 4 4 4 0 BED zinc finger DUF2256 PF10013.9 PXF42343.1 - 0.4 10.9 15.4 17 5.6 0.1 5.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_Hakai PF18408.1 PXF42343.1 - 0.45 10.3 18.3 0.39 10.5 0.2 4.5 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain zf_UBZ PF18439.1 PXF42343.1 - 0.56 9.8 21.6 10 5.8 0.5 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 PXF42343.1 - 1.1 9.2 22.6 0.66 10.0 2.1 3.5 3 2 0 3 3 3 0 zinc-ribbons zf-LITAF-like PF10601.9 PXF42343.1 - 1.2 9.4 19.2 0.079 13.2 5.7 3.5 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Rad50_zn_hook PF04423.14 PXF42343.1 - 1.5 8.7 13.4 2.1 8.3 0.2 4.1 4 0 0 4 4 4 0 Rad50 zinc hook motif HypA PF01155.19 PXF42343.1 - 2.1 8.4 17.5 0.28 11.2 0.2 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 PXF42343.1 - 2.9 8.2 13.3 1.4 9.2 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon Sgf11 PF08209.11 PXF42343.1 - 4.7 6.9 20.0 15 5.3 0.2 5.1 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Neisseria_TspB PF05616.13 PXF42343.1 - 8.7 4.7 11.6 14 4.0 11.6 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Peptidase_S49_N PF08496.10 PXF42344.1 - 5.7 7.0 9.8 9.4 6.3 9.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MutS_V PF00488.21 PXF42345.1 - 3.9e-60 203.1 0.1 6.2e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 PXF42345.1 - 2.1e-31 108.5 0.0 5e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 PXF42345.1 - 3e-29 102.6 3.1 6.2e-29 101.6 2.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 PXF42345.1 - 6.8e-07 29.5 0.4 1.6e-06 28.4 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PXF42345.1 - 4.9e-05 23.6 0.0 4.9e-05 23.6 0.0 2.6 3 0 0 3 3 3 1 MutS domain II AAA_16 PF13191.6 PXF42345.1 - 0.021 15.2 2.5 0.1 13.0 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 PXF42345.1 - 0.029 14.8 0.1 0.96 9.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PXF42345.1 - 0.046 13.9 0.3 16 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF4976 PF16347.5 PXF42345.1 - 0.16 12.3 0.5 0.41 10.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) FUSC PF04632.12 PXF42345.1 - 0.24 9.9 1.3 0.45 9.0 1.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-RING_2 PF13639.6 PXF42347.1 - 1.1e-13 51.3 5.6 2.2e-13 50.3 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF42347.1 - 9.3e-10 38.1 2.7 9.3e-10 38.1 2.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF42347.1 - 1.2e-09 37.9 5.0 3.6e-09 36.3 5.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF42347.1 - 8.7e-09 35.5 8.0 4.6e-08 33.2 8.0 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF42347.1 - 2.1e-07 30.7 4.8 4.6e-07 29.6 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF42347.1 - 1.5e-06 28.0 4.6 3.6e-06 26.8 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF42347.1 - 1.6e-05 24.8 0.3 1.6e-05 24.8 0.3 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF42347.1 - 0.00044 20.3 4.2 0.00088 19.3 3.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PXF42347.1 - 0.0013 18.5 7.2 0.0031 17.3 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 PXF42347.1 - 0.0017 18.3 4.6 0.006 16.6 4.6 2.0 1 1 0 1 1 1 1 Zinc-finger PHD PF00628.29 PXF42347.1 - 0.0034 17.3 5.6 0.0077 16.1 5.6 1.7 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 PXF42347.1 - 0.018 14.7 7.6 0.036 13.7 7.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 PXF42347.1 - 0.038 13.7 4.6 0.21 11.3 2.0 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 PXF42347.1 - 0.16 11.8 3.8 0.35 10.7 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PXF42347.1 - 0.24 11.3 9.0 0.57 10.1 9.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PXF42347.1 - 1.2 9.3 7.0 5.9 7.2 7.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Phage_int_SAM_1 PF02899.17 PXF42348.1 - 0.012 15.8 0.5 0.23 11.8 0.0 2.8 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 PXF42348.1 - 0.092 13.2 2.4 0.35 11.4 0.0 3.0 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain Oxidored_q2 PF00420.24 PXF42348.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RsfS PF02410.15 PXF42351.1 - 2.7e-20 72.6 0.0 4.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation EKR PF10371.9 PXF42351.1 - 0.032 14.0 0.1 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function ACP_PD PF04336.12 PXF42353.1 - 0.014 15.8 0.6 0.035 14.5 0.6 1.7 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase MutS_V PF00488.21 PXF42354.1 - 1.4e-46 158.9 0.1 6e-23 81.8 0.0 2.5 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 PXF42354.1 - 1.7e-20 74.0 0.4 1.7e-20 74.0 0.4 2.5 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 PXF42354.1 - 7.1e-07 29.5 1.0 7.1e-07 29.5 1.0 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 PXF42354.1 - 2.8e-05 24.4 0.4 0.00017 21.9 0.0 2.5 2 1 0 2 2 2 1 MutS domain II DUF2379 PF09543.10 PXF42354.1 - 0.02 15.1 5.2 0.078 13.2 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Acylphosphatase PF00708.18 PXF42355.1 - 3.1e-21 75.6 0.0 3.4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase Pkinase PF00069.25 PXF42357.1 - 3.6e-36 124.9 0.0 5.6e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42357.1 - 9.6e-19 67.7 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF42357.1 - 0.00011 22.2 1.2 0.00019 21.4 1.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF42357.1 - 0.17 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF563 PF04577.14 PXF42358.1 - 9.1e-16 58.6 0.5 2e-15 57.5 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pro_3_hydrox_C PF05373.11 PXF42361.1 - 0.026 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal DUF2373 PF10180.9 PXF42361.1 - 0.032 14.1 0.5 0.051 13.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cupin_8 PF13621.6 PXF42362.1 - 5e-43 147.6 0.6 5.9e-43 147.4 0.6 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PXF42362.1 - 2.3e-05 24.8 0.5 0.02 15.3 0.0 2.6 2 1 1 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 PXF42362.1 - 0.00034 20.2 0.2 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein DsbC_N PF10411.9 PXF42362.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus PWI PF01480.17 PXF42363.1 - 0.00021 21.6 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 PWI domain Acetyltransf_1 PF00583.25 PXF42364.1 - 5.1e-15 55.7 0.0 6.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF42364.1 - 2.4e-07 30.7 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF42364.1 - 3.5e-07 30.6 0.0 5.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF42364.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 PXF42364.1 - 0.00027 21.6 0.0 0.00035 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PXF42364.1 - 0.0012 18.9 0.1 0.0029 17.7 0.1 1.7 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 PXF42364.1 - 0.0096 15.7 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 GNAT acetyltransferase, Mec-17 PanZ PF12568.8 PXF42364.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 PXF42364.1 - 0.17 11.4 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF3459 PF11941.8 PXF42366.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3459) Mito_carr PF00153.27 PXF42369.1 - 7e-41 138.1 4.7 1.9e-16 59.7 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_trans_2_3 PF13632.6 PXF42370.1 - 1.7e-20 73.8 12.1 1.7e-20 73.8 12.1 3.9 3 2 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PXF42370.1 - 1.7e-06 28.1 1.5 4.8e-06 26.6 1.5 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PXF42370.1 - 0.037 13.5 0.3 0.36 10.3 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Sprouty PF05210.13 PXF42370.1 - 1.7 9.0 5.1 10 6.6 0.0 3.7 3 1 0 3 3 3 0 Sprouty protein (Spry) FMN_dh PF01070.18 PXF42371.1 - 3.1e-112 375.1 0.0 3.6e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 PXF42371.1 - 2.9e-06 26.5 1.8 1.7e-05 24.0 0.2 2.4 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 PXF42371.1 - 9.7e-05 21.8 6.2 0.0038 16.6 0.3 2.4 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 PXF42371.1 - 0.00011 21.5 0.4 0.00019 20.7 0.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 PXF42371.1 - 0.036 13.5 1.1 0.056 12.8 1.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 PXF42371.1 - 0.083 12.1 0.4 9.7 5.3 0.0 2.3 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 PXF42371.1 - 0.093 12.2 0.1 1.3 8.4 0.0 2.3 2 1 1 3 3 3 0 Histidine biosynthesis protein Epimerase PF01370.21 PXF42372.1 - 0.025 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PXF42372.1 - 0.025 13.7 0.1 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein BT1 PF03092.16 PXF42373.1 - 8.8e-108 360.8 14.2 1.3e-74 251.4 5.5 2.1 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 PXF42373.1 - 3.1e-07 29.8 0.1 3.1e-07 29.8 0.1 2.1 2 1 0 2 2 2 1 PUCC protein WD40 PF00400.32 PXF42374.1 - 2.2e-19 69.4 10.3 0.015 16.1 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42374.1 - 9.4e-08 32.3 0.2 0.12 12.7 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 PXF42374.1 - 0.00049 20.1 3.0 0.77 9.7 0.8 3.0 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 PXF42374.1 - 0.02 13.9 0.1 0.38 9.6 0.0 3.0 3 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Bud13 PF09736.9 PXF42375.1 - 0.46 10.9 12.8 0.53 10.7 12.8 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Rota_VP2 PF05087.12 PXF42375.1 - 1.2 7.2 9.4 1.2 7.1 9.4 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein bZIP_1 PF00170.21 PXF42376.1 - 0.00012 22.1 4.9 0.00012 22.1 4.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor GIT1_C PF12205.8 PXF42376.1 - 0.0035 17.5 1.0 0.0068 16.5 1.0 1.4 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term 3HCDH_N PF02737.18 PXF42376.1 - 0.064 13.1 1.7 0.12 12.2 1.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spc29 PF17082.5 PXF42376.1 - 0.1 12.5 4.0 0.14 12.0 4.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Jnk-SapK_ap_N PF09744.9 PXF42376.1 - 0.16 12.2 8.6 0.15 12.3 7.9 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DASH_Hsk3 PF08227.11 PXF42376.1 - 0.18 12.2 3.5 0.4 11.1 3.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like TEX13 PF15186.6 PXF42376.1 - 0.19 11.4 5.7 0.36 10.5 5.7 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family TPR_MLP1_2 PF07926.12 PXF42376.1 - 0.53 10.4 8.3 0.38 10.8 6.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 PXF42376.1 - 0.59 10.7 5.2 0.85 10.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 APG6_N PF17675.1 PXF42376.1 - 1.6 9.3 8.7 0.55 10.7 5.5 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region dCMP_cyt_deam_1 PF00383.23 PXF42377.1 - 3e-27 94.5 2.4 4.5e-27 93.9 2.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF42377.1 - 9.7e-15 54.5 0.7 1.7e-14 53.7 0.7 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_14 PF13173.6 PXF42377.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PXF42377.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Yippee-Mis18 PF03226.14 PXF42378.1 - 4.3e-12 46.2 0.1 5.1e-12 45.9 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 PXF42378.1 - 0.0052 16.8 0.1 0.0067 16.5 0.1 1.2 1 0 0 1 1 1 1 SelR domain zf-ribbon_3 PF13248.6 PXF42378.1 - 0.028 13.8 0.0 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 PXF42378.1 - 0.034 14.1 1.7 6.7 6.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 PXF42378.1 - 0.044 13.3 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.13 PXF42378.1 - 0.047 13.4 0.8 6.6 6.5 0.2 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 PXF42378.1 - 0.048 13.6 1.5 4.8 7.2 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 PXF42378.1 - 0.1 12.4 0.4 0.1 12.4 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 PXF42378.1 - 0.27 11.0 2.6 0.91 9.3 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_S13 PF00416.22 PXF42379.1 - 9.8e-25 87.4 0.1 4.4e-23 82.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 PXF42379.1 - 0.033 12.9 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Pyr_redox_2 PF07992.14 PXF42380.1 - 7e-69 232.3 0.9 9.9e-69 231.8 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PXF42380.1 - 5.1e-31 107.2 0.6 1e-30 106.2 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PXF42380.1 - 7.9e-21 74.4 1.9 3.1e-19 69.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF42380.1 - 9.7e-17 61.2 3.8 1.9e-16 60.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF42380.1 - 1.2e-08 34.0 1.0 0.00043 19.1 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 PXF42380.1 - 2.9e-07 30.0 0.1 5.2e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 PXF42380.1 - 0.0011 18.4 6.5 0.0038 16.6 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 PXF42380.1 - 0.0013 17.9 10.8 0.0018 17.5 0.8 3.4 3 1 1 4 4 4 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 PXF42380.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 PXF42380.1 - 0.0081 16.1 0.6 0.75 9.7 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 PXF42380.1 - 0.027 13.7 0.6 0.081 12.2 0.1 2.0 3 0 0 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 PXF42380.1 - 0.15 11.3 7.1 0.38 10.0 0.1 3.3 3 1 1 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 PXF42380.1 - 0.15 11.1 6.8 0.075 12.1 2.1 2.5 2 1 1 3 3 3 0 FAD binding domain DAO PF01266.24 PXF42380.1 - 0.39 10.2 0.0 0.39 10.2 0.0 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF42380.1 - 6.2 7.1 6.9 1 9.7 2.0 2.3 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain DUF218 PF02698.17 PXF42381.1 - 2.1e-11 43.9 0.3 1.1e-10 41.7 0.0 2.2 2 1 0 2 2 2 1 DUF218 domain PLAC9 PF15205.6 PXF42381.1 - 0.0093 16.3 0.8 1.3 9.4 0.1 2.7 2 0 0 2 2 2 2 Placenta-specific protein 9 Pkinase PF00069.25 PXF42382.1 - 2.3e-69 233.7 0.0 2.7e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42382.1 - 2.9e-33 115.3 0.0 3.6e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42382.1 - 1.8e-08 34.0 0.0 1.1e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF42382.1 - 0.00031 20.2 0.3 0.00073 18.9 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF42382.1 - 0.0015 18.5 0.3 0.0079 16.1 0.1 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 PXF42382.1 - 0.046 13.3 0.0 0.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PXF42382.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain FIST PF08495.10 PXF42383.1 - 2.7e-21 76.3 1.8 3.2e-21 76.1 0.2 1.8 2 1 0 2 2 2 1 FIST N domain FIST_C PF10442.9 PXF42383.1 - 1.4e-10 41.3 0.0 2.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 FIST C domain YwiC PF14256.6 PXF42384.1 - 0.11 12.8 8.7 0.078 13.3 3.7 2.2 2 0 0 2 2 2 0 YwiC-like protein Scramblase PF03803.15 PXF42385.1 - 3.2e-50 170.5 0.0 4.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase DapB_C PF05173.14 PXF42386.1 - 1.2e-18 67.3 0.9 1.9e-18 66.6 0.9 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 PXF42386.1 - 3.3e-11 43.4 0.0 7.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Lipocalin_5 PF13924.6 PXF42386.1 - 0.0084 15.9 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 1 Lipocalin-like domain Abhydrolase_6 PF12697.7 PXF42387.1 - 0.022 15.4 0.1 0.024 15.2 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1295 PF06966.12 PXF42388.1 - 3e-41 141.5 4.3 4.7e-41 140.9 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 PXF42388.1 - 0.00055 19.9 0.2 0.0021 18.1 0.2 2.0 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 PXF42388.1 - 0.0061 16.9 0.4 0.0061 16.9 0.4 3.0 3 2 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EMC3_TMCO1 PF01956.16 PXF42388.1 - 0.034 13.9 1.8 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PEMT PF04191.13 PXF42388.1 - 0.059 13.8 0.5 0.059 13.8 0.5 2.3 2 0 0 2 2 2 0 Phospholipid methyltransferase TPR_9 PF13371.6 PXF42389.1 - 0.22 11.7 1.0 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 PXF42390.1 - 1e-11 44.2 0.0 1.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.6 PXF42390.1 - 0.0068 16.6 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain Helicase_C PF00271.31 PXF42390.1 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SRP54 PF00448.22 PXF42391.1 - 1.7e-75 253.0 0.4 3.1e-75 252.1 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PXF42391.1 - 1.3e-30 105.9 1.9 4.4e-30 104.2 1.9 2.0 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 PXF42391.1 - 4.1e-20 71.8 4.5 1.2e-19 70.2 4.5 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 PXF42391.1 - 0.00018 21.7 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 PXF42391.1 - 0.0033 17.0 0.1 0.017 14.7 0.1 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 PXF42391.1 - 0.016 14.2 0.1 0.99 8.3 0.0 2.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4788 PF16032.5 PXF42391.1 - 0.059 12.3 0.1 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) Flavi_NS1 PF00948.21 PXF42391.1 - 0.12 11.3 0.2 0.2 10.5 0.2 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 MMR_HSR1 PF01926.23 PXF42391.1 - 0.55 10.3 0.0 0.55 10.3 0.0 2.6 4 0 0 4 4 4 0 50S ribosome-binding GTPase Pkinase PF00069.25 PXF42392.1 - 5.9e-39 134.0 0.0 7.1e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42392.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF42392.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HAP1_N PF04849.13 PXF42394.1 - 0.11 11.7 20.7 0.22 10.7 9.3 3.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 PXF42394.1 - 0.22 11.6 16.8 1.1 9.4 0.1 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 PXF42394.1 - 0.24 11.6 4.8 1.5 9.1 0.6 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG GIT_CC PF16559.5 PXF42394.1 - 0.27 11.1 8.4 2.3 8.2 0.0 3.6 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 PXF42394.1 - 0.43 9.9 21.2 1.4 8.2 10.5 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 PXF42394.1 - 0.77 10.5 18.8 6 7.6 0.9 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4472) LapA_dom PF06305.11 PXF42394.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.7 4 0 0 4 4 3 0 Lipopolysaccharide assembly protein A domain ATG16 PF08614.11 PXF42394.1 - 1.5 9.0 27.3 2.3 8.4 16.9 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 PXF42394.1 - 1.9 9.1 17.0 10 6.8 0.4 3.7 2 1 1 3 3 3 0 Initiation control protein YabA XhlA PF10779.9 PXF42394.1 - 1.9 8.7 14.8 0.32 11.2 0.3 4.3 2 1 2 4 4 4 0 Haemolysin XhlA FUSC PF04632.12 PXF42394.1 - 2.2 6.7 7.5 7.2 5.0 7.3 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family YtxH PF12732.7 PXF42394.1 - 2.6 8.6 4.8 5.2 7.7 0.3 3.3 2 2 0 2 2 2 0 YtxH-like protein APG6_N PF17675.1 PXF42394.1 - 3.8 8.0 27.8 12 6.4 4.4 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 PXF42394.1 - 8.4 5.2 24.6 1 8.2 1.3 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Pam16 PF03656.13 PXF42395.1 - 2.4e-21 76.1 0.1 3e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 PXF42395.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain Tetraspanin PF00335.20 PXF42396.1 - 2.2e-13 50.5 6.9 2.5e-13 50.3 6.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2167 PF09935.9 PXF42396.1 - 0.31 10.2 0.3 0.46 9.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) DUF2157 PF09925.9 PXF42396.1 - 0.6 9.9 8.5 0.67 9.7 4.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) ALAD PF00490.21 PXF42397.1 - 1.1e-133 445.3 0.0 1.3e-133 445.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PRAI PF00697.22 PXF42398.1 - 1.3e-24 87.0 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CBS PF00571.28 PXF42399.1 - 7.3e-22 77.6 5.1 5.4e-13 49.2 0.6 2.5 2 1 1 3 3 3 2 CBS domain PrmA PF06325.13 PXF42400.1 - 6e-12 45.6 0.0 9.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PXF42400.1 - 4e-10 40.3 0.0 9.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF42400.1 - 5.7e-09 36.5 0.1 1.8e-08 34.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF42400.1 - 5.7e-08 32.7 0.3 1.9e-07 31.0 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF42400.1 - 1.7e-07 30.9 0.1 2.7e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PXF42400.1 - 3.2e-06 27.2 0.1 5.5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF42400.1 - 6.9e-06 25.6 0.2 9.8e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 PXF42400.1 - 1.3e-05 25.1 0.0 2.5e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 PXF42400.1 - 1.5e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 PXF42400.1 - 0.00017 21.4 0.1 0.00027 20.7 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 PXF42400.1 - 0.00018 22.2 0.0 0.00032 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PXF42400.1 - 0.00029 20.3 0.6 0.00076 18.9 0.6 1.7 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 PXF42400.1 - 0.00041 19.4 0.1 0.00067 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PXF42400.1 - 0.0094 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 PXF42400.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 PXF42400.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 PXF42400.1 - 0.02 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase NodS PF05401.11 PXF42400.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PXF42400.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 PXF42400.1 - 0.21 11.2 1.3 1.7 8.3 1.3 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FPL PF09758.9 PXF42402.1 - 8.2e-39 133.0 4.0 1.1e-31 109.9 2.6 2.7 2 0 0 2 2 2 2 Uncharacterised conserved protein DNA_primase_lrg PF04104.14 PXF42403.1 - 1.3e-65 221.4 0.0 2e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Optomotor-blind PF11078.8 PXF42403.1 - 0.09 13.3 0.5 1.2 9.8 0.1 2.5 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region eIF2A PF08662.11 PXF42404.1 - 5.8e-48 163.4 0.3 1.7e-44 152.0 0.1 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 PXF42404.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 PXF42404.1 - 0.0085 14.1 0.0 0.0085 14.1 0.0 2.2 3 0 0 3 3 3 1 IKI3 family HEAT_UF PF18817.1 PXF42404.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 PPE PF00823.19 PXF42404.1 - 0.079 13.1 0.4 0.13 12.4 0.4 1.2 1 0 0 1 1 1 0 PPE family DUF2852 PF11014.8 PXF42404.1 - 0.16 12.1 0.9 0.4 10.8 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF4446 PF14584.6 PXF42404.1 - 0.68 9.9 2.1 1.3 9.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4355 PF14265.6 PXF42404.1 - 1 9.6 11.4 2.4 8.4 11.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Cmc1 PF08583.10 PXF42405.1 - 2.1e-13 50.1 0.6 3e-13 49.6 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PXF42405.1 - 0.02 15.0 1.4 0.21 11.7 1.4 2.1 1 1 0 1 1 1 0 CHCH domain Plant_tran PF04827.14 PXF42407.1 - 1.2e-23 83.8 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Fas_alpha_ACP PF18325.1 PXF42407.1 - 0.21 11.9 0.0 11 6.3 0.0 2.1 2 0 0 2 2 2 0 Fatty acid synthase subunit alpha Acyl carrier domain OTU PF02338.19 PXF42411.1 - 1.1e-06 29.1 0.0 3.2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 PXF42411.1 - 0.039 14.4 0.2 0.15 12.6 0.2 2.0 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Rad60-SLD_2 PF13881.6 PXF42411.1 - 0.14 12.3 0.6 19 5.4 0.0 3.2 3 1 1 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like HalOD2 PF18547.1 PXF42411.1 - 0.15 12.0 0.3 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Halobacterial output domain 2 zf-UBP PF02148.19 PXF42411.1 - 0.21 11.9 1.0 0.39 11.1 0.3 1.7 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_2 PF12756.7 PXF42411.1 - 0.33 11.3 2.9 0.63 10.4 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_M14 PF00246.24 PXF42412.1 - 8.8e-17 61.8 0.0 2.2e-14 53.9 0.0 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase Pkinase PF00069.25 PXF42414.1 - 3.6e-70 236.3 0.0 5.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42414.1 - 1.8e-35 122.5 0.0 3.2e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42414.1 - 1.4e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF42414.1 - 7.9e-05 22.1 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF42414.1 - 0.00032 19.6 1.4 0.00054 18.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 PXF42414.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 PH domain Trp_oprn_chp PF09534.10 PXF42415.1 - 0.094 12.5 3.6 0.36 10.6 3.6 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AC_N PF16214.5 PXF42415.1 - 0.64 9.1 3.4 0.95 8.5 3.4 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CLP_protease PF00574.23 PXF42416.1 - 3.2e-60 203.1 0.0 3.9e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease DUF21 PF01595.20 PXF42417.1 - 2.5e-36 125.0 5.9 3.8e-36 124.4 5.9 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 PXF42417.1 - 1.8e-18 66.3 0.1 4.5e-17 61.8 0.0 2.7 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 PXF42417.1 - 9e-14 51.7 0.3 3e-08 34.0 0.1 2.9 3 0 0 3 3 3 2 CBS domain DUF2975 PF11188.8 PXF42417.1 - 0.7 9.8 5.3 0.21 11.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) VKOR PF07884.14 PXF42418.1 - 3.6e-24 85.3 10.5 6.5e-24 84.5 10.5 1.4 1 0 0 1 1 1 1 Vitamin K epoxide reductase family SAM_1 PF00536.30 PXF42419.1 - 5.9e-07 29.8 0.1 1.1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PXF42419.1 - 0.00021 21.3 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinocilin PF15033.6 PXF42419.1 - 0.16 11.6 6.9 0.19 11.4 5.8 1.6 1 1 0 1 1 1 0 Kinocilin protein Pkinase PF00069.25 PXF42421.1 - 6e-17 61.9 0.0 7.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42421.1 - 2e-07 30.6 0.0 2.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF42421.1 - 6.9e-05 22.9 0.1 8.1e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF42421.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF42421.1 - 0.0037 16.9 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Baculo_p47 PF05112.12 PXF42421.1 - 0.063 12.9 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein RIO1 PF01163.22 PXF42421.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 RIO1 family CDT1_C PF16679.5 PXF42422.1 - 0.0043 17.4 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain PCI PF01399.27 PXF42423.1 - 3.3e-05 24.3 0.0 5.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PCI domain Mobilization_B PF17511.2 PXF42423.1 - 0.032 14.6 0.2 0.057 13.8 0.1 1.4 1 1 0 1 1 1 0 Mobilization protein B IMD PF08397.11 PXF42424.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain Helicase_C PF00271.31 PXF42425.1 - 3e-12 46.8 0.0 5.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EndoU_bacteria PF14436.6 PXF42425.1 - 0.091 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial EndoU nuclease Sec7 PF01369.20 PXF42426.1 - 4.3e-24 85.2 0.3 4.6e-24 85.1 0.3 1.0 1 0 0 1 1 1 1 Sec7 domain EzrA PF06160.12 PXF42433.1 - 0.015 13.6 1.5 0.02 13.1 1.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF42433.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CT_A_B PF02626.15 PXF42434.1 - 8.5e-75 251.8 0.0 1.4e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 PXF42434.1 - 5e-61 205.9 0.1 8.7e-61 205.1 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 PXF42434.1 - 6.3e-43 146.9 0.0 1.2e-42 146.0 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Amidase PF01425.21 PXF42434.1 - 3.2e-33 115.4 0.2 5e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 Amidase Biotin_carb_N PF00289.22 PXF42434.1 - 4e-30 104.6 0.2 1.6e-29 102.6 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PXF42434.1 - 1e-28 99.6 0.0 3.8e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PXF42434.1 - 5.7e-14 51.7 0.7 1.4e-13 50.5 0.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PXF42434.1 - 2.2e-09 37.2 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PXF42434.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 PXF42434.1 - 0.0066 15.7 0.1 1.8 7.7 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 PXF42434.1 - 0.037 14.7 0.6 6.7 7.5 0.1 2.7 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 PXF42434.1 - 0.044 13.6 4.3 0.085 12.7 0.0 3.4 3 1 1 4 4 4 0 Biotin-lipoyl like ATP-grasp_3 PF02655.14 PXF42434.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_S9 PF00326.21 PXF42437.1 - 3.2e-10 39.9 0.0 7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PXF42437.1 - 3.2e-09 36.4 0.0 0.0002 20.7 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF42437.1 - 0.00023 20.9 0.0 0.18 11.4 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 PXF42437.1 - 0.00027 20.6 0.0 0.00059 19.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 PXF42437.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 PXF42437.1 - 0.14 12.0 0.1 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PXF42437.1 - 0.23 11.0 0.0 0.66 9.5 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) RRM_1 PF00076.22 PXF42438.1 - 7e-40 134.7 0.0 8.2e-20 70.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PXF42438.1 - 0.005 16.8 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PXF42438.1 - 0.0095 16.0 0.0 0.38 10.9 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 PXF42438.1 - 0.01 15.5 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ephrin_rec_like PF07699.13 PXF42439.1 - 2.5e-18 65.6 51.7 1.3e-06 28.1 4.5 7.4 3 3 4 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 PXF42439.1 - 2.6e-05 24.1 41.1 0.03 14.3 0.5 6.9 3 1 1 7 7 7 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PXF42439.1 - 0.023 15.1 43.0 1.5 9.3 1.9 8.6 4 3 4 8 8 8 0 TNFR/NGFR cysteine-rich region WD40 PF00400.32 PXF42440.1 - 2.5e-21 75.6 18.9 2.7e-06 28.0 0.5 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42440.1 - 8.5e-08 32.4 2.3 0.32 11.3 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PXF42440.1 - 0.0027 16.3 0.3 0.77 8.2 0.0 2.8 2 1 0 2 2 2 2 Cytochrome D1 heme domain PilI PF10623.9 PXF42440.1 - 0.067 13.4 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI Ldh_2 PF02615.14 PXF42441.1 - 6e-106 354.4 0.0 7e-106 354.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Phage_TAC_7 PF10109.9 PXF42442.1 - 0.22 11.6 2.3 0.27 11.4 0.1 2.3 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 DUF2975 PF11188.8 PXF42442.1 - 1.9 8.4 7.2 0.18 11.7 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) TMPIT PF07851.13 PXF42442.1 - 2.9 7.1 22.1 0.079 12.2 2.2 2.7 2 1 1 3 3 3 0 TMPIT-like protein DUF5339 PF17274.2 PXF42442.1 - 2.9 8.8 14.8 14 6.6 7.5 3.3 1 1 0 2 2 2 0 Family of unknown function (DUF5339) DUF4954 PF16314.5 PXF42442.1 - 3.9 5.5 6.8 5.9 4.9 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Macoilin PF09726.9 PXF42442.1 - 7.6 5.0 28.9 9.6 4.6 28.9 1.1 1 0 0 1 1 1 0 Macoilin family RNase_E_G PF10150.9 PXF42442.1 - 9.8 5.5 22.2 1.3 8.4 11.3 2.9 2 1 1 3 3 3 0 Ribonuclease E/G family Rhodanese PF00581.20 PXF42443.1 - 7.7e-18 65.0 0.0 8.8e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain zf-RING_2 PF13639.6 PXF42444.1 - 9.6e-11 41.8 11.6 1.3e-10 41.4 11.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF42444.1 - 1.7e-09 37.3 9.6 2.9e-09 36.5 9.6 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF42444.1 - 1.2e-06 28.7 9.2 2.1e-06 27.9 9.2 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF42444.1 - 1.5e-05 24.7 10.9 2.3e-05 24.1 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF42444.1 - 0.00095 19.0 11.4 0.0014 18.4 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2856 PF11043.8 PXF42444.1 - 0.0046 17.0 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2856) Zn_ribbon_17 PF17120.5 PXF42444.1 - 0.0063 16.1 10.0 0.0086 15.7 10.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 PXF42444.1 - 0.0068 16.4 10.2 0.01 15.8 10.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 PXF42444.1 - 0.051 13.8 10.5 0.15 12.2 10.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 PXF42444.1 - 0.11 12.5 11.4 0.18 11.8 11.4 1.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF42444.1 - 0.16 12.0 7.8 0.35 10.9 7.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 PXF42444.1 - 0.2 11.8 8.6 0.47 10.6 8.6 1.7 1 1 0 1 1 1 0 RING-variant domain Ribosomal_S8 PF00410.19 PXF42445.1 - 2e-21 76.2 0.0 3.8e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 MIP PF00230.20 PXF42446.1 - 4.4e-19 69.1 4.6 7.3e-19 68.4 4.6 1.3 1 0 0 1 1 1 1 Major intrinsic protein AzlD PF05437.12 PXF42446.1 - 0.58 10.4 8.7 0.38 11.0 1.4 3.0 2 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DUF3487 PF11990.8 PXF42446.1 - 4.3 7.3 6.8 0.63 9.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Ribosomal_L21e PF01157.18 PXF42447.1 - 2.8e-40 136.2 3.7 4.9e-40 135.5 3.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Trypan_PARP PF05887.11 PXF42448.1 - 0.094 12.7 60.0 0.46 10.5 60.0 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA-synt_2 PF00152.20 PXF42450.1 - 7e-76 255.3 0.0 9.5e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PXF42450.1 - 1e-07 31.8 0.3 1.7e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF42450.1 - 0.00055 19.5 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CK1gamma_C PF12605.8 PXF42450.1 - 0.26 12.5 0.9 14 6.9 0.0 2.6 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal His_Phos_2 PF00328.22 PXF42451.1 - 6.8e-13 48.7 6.2 1.4e-09 37.8 0.8 3.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HhH-GPD PF00730.25 PXF42452.1 - 2.8e-10 40.6 0.0 6.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 PXF42452.1 - 1.2e-06 28.6 7.4 3e-06 27.4 7.4 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III BSMAP PF12280.8 PXF42453.1 - 0.1 12.8 0.6 0.24 11.6 0.2 1.7 2 0 0 2 2 2 0 Brain specific membrane anchored protein Pyr_redox_2 PF07992.14 PXF42454.1 - 1.1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF42454.1 - 0.0024 17.9 0.0 0.016 15.2 0.0 2.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PXF42454.1 - 0.0025 18.0 0.0 0.015 15.5 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PXF42454.1 - 0.032 12.9 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PXF42454.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 PXF42454.1 - 0.096 11.8 0.0 9 5.3 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Piwi PF02171.17 PXF42455.1 - 1e-77 261.4 0.0 1.8e-77 260.6 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 PXF42455.1 - 2.3e-15 57.4 0.0 6.3e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 PXF42455.1 - 1.1e-07 32.0 0.1 6.5e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 PXF42455.1 - 7.6e-07 28.7 0.1 1.6e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 PXF42455.1 - 0.0014 18.9 0.3 0.0099 16.1 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute DUF2974 PF11187.8 PXF42456.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 PXF42456.1 - 0.0003 21.0 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 PXF42456.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 PXF42456.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 PXF42456.1 - 0.087 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) WD40 PF00400.32 PXF42457.1 - 4.5e-49 163.4 46.1 1.2e-08 35.4 0.4 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42457.1 - 1.7e-22 79.5 12.7 0.0022 18.2 0.0 9.4 3 1 8 11 11 11 8 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF42457.1 - 3.4e-15 55.8 9.7 0.16 10.9 0.0 8.5 1 1 7 8 8 8 6 WD40 region of Ge1, enhancer of mRNA-decapping protein NB-ARC PF00931.22 PXF42457.1 - 1.4e-11 44.1 0.1 2.5e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain Gmad1 PF10647.9 PXF42457.1 - 0.0016 18.2 9.1 1.4 8.6 0.9 5.1 1 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 PXF42457.1 - 0.0034 16.8 0.0 11 5.2 0.0 4.2 3 1 1 4 4 4 1 WD40-like domain PD40 PF07676.12 PXF42457.1 - 0.0037 17.2 1.5 9.4 6.3 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PXF42457.1 - 0.006 15.3 11.0 4 6.0 0.1 5.9 5 1 0 5 5 5 2 Nucleoporin Nup120/160 APAF1_C PF17908.1 PXF42457.1 - 0.0076 16.2 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 APAF-1 helical domain FeThRed_A PF02941.15 PXF42457.1 - 0.077 13.1 1.3 4.2 7.6 0.1 3.1 2 1 1 3 3 3 0 Ferredoxin thioredoxin reductase variable alpha chain Methyltransf_25 PF13649.6 PXF42458.1 - 1.6e-15 57.6 0.0 4.1e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF42458.1 - 9e-15 55.1 0.0 2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF42458.1 - 4.2e-09 37.0 0.0 1.1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF42458.1 - 1.3e-08 34.4 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF42458.1 - 1.7e-07 31.1 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF42458.1 - 3.8e-07 30.1 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 PXF42458.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 PXF42458.1 - 0.023 14.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 PXF42458.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase GCD14 PF08704.10 PXF42466.1 - 1.1e-28 100.6 0.3 1.2e-28 100.5 0.3 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Na_Ca_ex PF01699.24 PXF42467.1 - 4.9e-38 130.4 30.6 1.8e-19 70.2 6.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4342 PF14242.6 PXF42467.1 - 0.17 11.9 1.3 1.4 9.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) La PF05383.17 PXF42468.1 - 1.7e-14 53.6 0.0 3.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 La domain zf-CCCH_3 PF15663.5 PXF42469.1 - 0.13 12.5 9.9 0.025 14.8 4.6 2.5 1 1 0 2 2 2 0 Zinc-finger containing family Mucin PF01456.17 PXF42469.1 - 0.2 11.6 23.7 1.2 9.1 11.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein CFIA_Pcf11 PF11526.8 PXF42469.1 - 2.4 8.7 13.9 0.61 10.6 2.9 2.6 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 zf-CCCH PF00642.24 PXF42469.1 - 2.5 8.1 12.7 2 8.4 3.5 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PXF42469.1 - 3.5 7.8 17.5 0.13 12.3 1.5 3.6 4 0 0 4 4 4 0 Zinc finger domain BAF1_ABF1 PF04684.13 PXF42469.1 - 6.1 5.8 15.7 1.1 8.3 2.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TIMP PF00965.17 PXF42471.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase DUF2270 PF10028.9 PXF42472.1 - 0.29 10.7 0.2 0.42 10.2 0.2 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Ndc1_Nup PF09531.10 PXF42472.1 - 1.9 7.1 12.0 2 7.0 12.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spore_SspJ PF09575.10 PXF42472.1 - 3.2 8.2 9.2 13 6.2 0.8 3.2 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) Nucleo_P87 PF07267.11 PXF42472.1 - 5.7 5.7 7.9 6.6 5.5 7.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1719 PF08224.11 PXF42474.1 - 0.042 13.0 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) RVT_2 PF07727.14 PXF42475.1 - 2.5e-16 60.0 0.1 3.3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acetyltransf_1 PF00583.25 PXF42476.1 - 6.6e-10 39.2 0.0 1.3e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF42476.1 - 2.1e-08 34.5 0.0 3.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF42476.1 - 2.4e-07 30.7 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF42476.1 - 7.8e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PXF42476.1 - 0.00016 21.8 0.2 0.00058 19.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 PXF42476.1 - 0.00034 20.3 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 PXF42476.1 - 0.0046 17.6 0.0 0.011 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 PXF42476.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Malectin PF11721.8 PXF42477.1 - 2.3e-16 60.3 0.0 2.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Malectin domain Malectin_like PF12819.7 PXF42477.1 - 0.0045 16.2 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Malectin-like domain DDE_Tnp_ISAZ013 PF07592.11 PXF42478.1 - 0.04 12.9 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DnaJ PF00226.31 PXF42486.1 - 3.3e-06 27.1 0.0 7.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MULE PF10551.9 PXF42487.1 - 0.00065 20.1 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain zf-C2HC_2 PF13913.6 PXF42489.1 - 0.00027 20.7 0.6 0.00027 20.7 0.6 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PXF42489.1 - 0.077 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42489.1 - 0.12 13.3 0.3 0.39 11.7 0.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger HTH_23 PF13384.6 PXF42489.1 - 0.14 12.0 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DNA_photolyase PF00875.18 PXF42490.1 - 1e-22 80.9 0.9 2.1e-22 79.9 0.5 1.7 1 1 1 2 2 2 1 DNA photolyase Limkain-b1 PF11608.8 PXF42491.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DUF3187 PF11383.8 PXF42491.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) Asparaginase_2 PF01112.18 PXF42492.1 - 9.9e-60 202.1 7.1 1.3e-59 201.8 7.1 1.0 1 0 0 1 1 1 1 Asparaginase CDP-OH_P_transf PF01066.21 PXF42493.1 - 6.8e-10 39.6 0.3 6.8e-10 39.6 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NDK PF00334.19 PXF42494.1 - 3e-52 176.2 0.0 3.4e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SpoU_methylase PF00588.19 PXF42495.1 - 6e-29 101.0 0.0 6.9e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family NETI PF14044.6 PXF42495.1 - 0.1 12.4 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 NETI protein LigT_PEase PF02834.16 PXF42496.1 - 4e-16 59.0 0.1 4.1e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 PXF42496.1 - 6.5e-11 42.4 0.0 9.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Pkinase PF00069.25 PXF42497.1 - 1.5e-71 240.9 0.0 2e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42497.1 - 1.8e-37 129.1 0.0 2.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42497.1 - 2.5e-09 36.9 0.0 7.2e-07 28.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 PXF42497.1 - 6.4e-06 25.7 0.3 6.4e-06 25.7 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF42497.1 - 0.00019 20.4 0.3 0.00053 18.9 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 PXF42497.1 - 0.00022 21.7 0.2 0.00076 20.0 0.0 2.0 2 0 0 2 2 2 1 PH domain APH PF01636.23 PXF42497.1 - 0.00031 20.8 0.5 0.85 9.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF42497.1 - 0.0069 16.0 0.3 0.0069 16.0 0.3 2.0 2 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 PXF42497.1 - 0.045 13.4 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CHASE3 PF05227.13 PXF42497.1 - 3.3 7.6 5.6 0.51 10.3 1.5 1.7 2 0 0 2 2 2 0 CHASE3 domain DUF2150 PF09920.9 PXF42499.1 - 0.045 13.7 4.6 0.059 13.4 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) DUF3829 PF12889.7 PXF42500.1 - 0.14 11.6 5.6 0.2 11.1 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) AIM3 PF17096.5 PXF42500.1 - 1.3 10.0 10.2 3.4 8.7 1.7 2.3 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF4407 PF14362.6 PXF42500.1 - 3.3 7.0 11.9 4.7 6.5 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 PXF42500.1 - 8.6 6.5 8.9 2.4 8.3 0.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 PXF42501.1 - 0.14 11.6 5.6 0.2 11.1 5.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) AIM3 PF17096.5 PXF42501.1 - 1.3 10.0 10.2 3.4 8.7 1.7 2.3 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF4407 PF14362.6 PXF42501.1 - 3.3 7.0 11.9 4.7 6.5 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 PXF42501.1 - 8.6 6.5 8.9 2.4 8.3 0.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Fib_alpha PF08702.10 PXF42502.1 - 4.4 7.5 10.3 0.68 10.1 1.3 2.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 PXF42502.1 - 4.8 6.5 13.2 7 5.9 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIM3 PF17096.5 PXF42502.1 - 8.1 7.5 10.5 19 6.2 1.9 2.3 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 Scramblase PF03803.15 PXF42507.1 - 0.074 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Scramblase Metallophos PF00149.28 PXF42508.1 - 2.7e-10 41.1 0.0 4.5e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ChuX_HutX PF06228.13 PXF42509.1 - 9.3e-05 22.2 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX DNA_pol_B PF00136.21 PXF42510.1 - 1.2e-98 330.8 0.0 1.6e-98 330.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PXF42510.1 - 9.1e-20 71.1 0.0 5.2e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PXF42510.1 - 0.00013 22.3 4.8 0.00013 22.3 4.8 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta zinc_ribbon_11 PF11682.8 PXF42510.1 - 0.21 11.6 1.0 0.56 10.2 0.3 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon Nop25 PF09805.9 PXF42511.1 - 1.5e-08 35.2 27.4 1.5e-08 35.2 27.4 2.4 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) MIP PF00230.20 PXF42512.1 - 2.1e-26 93.0 2.1 2.6e-26 92.8 2.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein TerC PF03741.16 PXF42512.1 - 0.0067 16.1 1.6 0.11 12.2 0.7 2.4 1 1 0 2 2 2 1 Integral membrane protein TerC family DUF3180 PF11377.8 PXF42512.1 - 0.35 11.0 6.0 1.5 9.0 0.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) DUF4418 PF14387.6 PXF42512.1 - 0.64 10.2 4.6 0.51 10.5 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) Alpha-amylase PF00128.24 PXF42517.1 - 5.5e-15 55.8 0.0 7.5e-08 32.3 0.0 3.5 2 1 1 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 PXF42517.1 - 6.2e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_M41 PF01434.18 PXF42518.1 - 9.7e-67 224.5 0.0 1.7e-66 223.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PXF42518.1 - 2e-45 154.5 0.0 4.6e-45 153.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF42518.1 - 9.7e-12 44.5 0.0 2.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PXF42518.1 - 2.6e-05 24.2 0.4 0.00013 22.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PXF42518.1 - 0.00015 21.1 0.1 0.00035 19.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PXF42518.1 - 0.00037 20.3 0.0 0.0021 17.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 PXF42518.1 - 0.0018 18.6 0.3 0.0046 17.3 0.0 1.9 2 0 0 2 2 1 1 FtsH Extracellular AAA_16 PF13191.6 PXF42518.1 - 0.0019 18.6 2.6 0.033 14.6 0.1 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 PXF42518.1 - 0.0022 18.1 0.2 0.023 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 PXF42518.1 - 0.0092 15.5 0.3 0.4 10.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 PXF42518.1 - 0.02 15.2 0.1 0.3 11.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PXF42518.1 - 0.022 15.3 0.0 0.053 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PXF42518.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PXF42518.1 - 0.027 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 PXF42518.1 - 0.031 14.4 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PXF42518.1 - 0.034 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PXF42518.1 - 0.046 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 PXF42518.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3670 PF12419.8 PXF42518.1 - 0.073 12.9 0.2 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 SNF2 Helicase protein NACHT PF05729.12 PXF42518.1 - 0.11 12.3 0.0 0.4 10.6 0.0 2.0 1 0 0 1 1 1 0 NACHT domain ACC_epsilon PF13822.6 PXF42518.1 - 0.8 10.4 9.5 2.3 9.0 9.5 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit TFIID_20kDa PF03847.13 PXF42519.1 - 1.1e-24 86.7 0.1 1.5e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 PXF42519.1 - 0.00011 22.4 0.1 0.00037 20.7 0.1 1.8 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF42519.1 - 0.0038 17.6 0.0 0.0056 17.0 0.0 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PXF42519.1 - 0.1 12.7 0.6 2.6 8.2 0.0 2.1 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold RACo_linker PF17650.1 PXF42520.1 - 0.0018 18.1 0.6 0.1 12.5 0.1 2.8 1 1 1 2 2 2 1 RACo linker region Fez1 PF06818.15 PXF42520.1 - 0.016 15.7 3.5 0.035 14.6 3.5 1.6 1 0 0 1 1 1 0 Fez1 TolA_bind_tri PF16331.5 PXF42520.1 - 0.079 13.0 9.4 2.5 8.2 0.5 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Spc7 PF08317.11 PXF42520.1 - 0.19 10.6 3.7 0.39 9.6 3.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 PXF42520.1 - 0.29 11.2 6.8 6.2 6.9 0.2 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 PXF42520.1 - 0.48 10.8 2.1 1.1 9.7 1.0 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain GAS PF13851.6 PXF42520.1 - 1 8.7 4.3 0.75 9.1 0.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 PXF42520.1 - 2.4 8.5 7.7 1 9.7 2.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF2291 PF10054.9 PXF42522.1 - 0.033 13.9 1.9 0.055 13.2 1.9 1.6 1 1 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) DUF4407 PF14362.6 PXF42522.1 - 0.13 11.6 6.7 0.16 11.3 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 PXF42522.1 - 0.16 12.2 9.6 0.12 12.6 3.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CSN5_C PF18323.1 PXF42522.1 - 0.94 10.4 7.7 12 6.8 7.7 2.4 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain LprI PF07007.12 PXF42522.1 - 1.1 10.0 8.3 0.49 11.1 5.9 1.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI LPP PF04728.13 PXF42522.1 - 4.9 7.6 9.2 6.2 7.3 0.1 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Glycoprot_B_PH1 PF17416.2 PXF42524.1 - 0.0019 17.9 0.3 0.0036 16.9 0.3 1.5 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Peptidase_C48 PF02902.19 PXF42524.1 - 0.02 14.8 0.3 0.039 13.8 0.3 1.4 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Peptidase_C39 PF03412.15 PXF42524.1 - 0.028 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Fer2 PF00111.27 PXF42527.1 - 3.8e-06 26.8 0.9 1.2e-05 25.2 0.9 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TolA PF06519.11 PXF42527.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 TolA C-terminal Thoc2 PF11732.8 PXF42527.1 - 0.13 12.4 0.0 0.36 10.9 0.0 1.8 1 1 1 2 2 2 0 Transcription- and export-related complex subunit Asp_Glu_race PF01177.22 PXF42528.1 - 0.0014 18.6 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase RPW8 PF05659.11 PXF42530.1 - 0.014 15.1 0.2 0.061 13.0 0.2 2.1 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Goodbye PF17109.5 PXF42530.1 - 0.019 15.4 0.8 0.065 13.7 0.8 2.0 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Rx_N PF18052.1 PXF42530.1 - 0.091 13.1 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Rx N-terminal domain Seryl_tRNA_N PF02403.22 PXF42530.1 - 1.4 9.2 6.6 8.5 6.7 0.1 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phytoreo_P8 PF07124.11 PXF42531.1 - 0.019 13.9 0.8 0.068 12.1 0.8 1.7 1 1 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DEC-1_N PF04625.13 PXF42534.1 - 7.1 5.5 7.6 9.7 5.1 7.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Sushi PF00084.20 PXF42542.1 - 0.038 14.6 0.1 6.4 7.5 0.1 3.2 2 1 1 3 3 3 0 Sushi repeat (SCR repeat) Lactamase_B_2 PF12706.7 PXF42543.1 - 3.8e-19 69.0 0.0 8.2e-19 67.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF42543.1 - 3.6e-11 43.5 0.0 5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 PXF42543.1 - 8.5e-05 22.5 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SRF-TF PF00319.18 PXF42545.1 - 8.4e-22 76.4 0.0 1.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) eIF-3_zeta PF05091.12 PXF42545.1 - 0.6 9.0 6.2 0.92 8.4 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Antimicrobial21 PF14861.6 PXF42546.1 - 0.0046 16.6 0.1 0.0046 16.6 0.1 3.8 4 1 0 4 4 4 1 Plant antimicrobial peptide Cpn60_TCP1 PF00118.24 PXF42547.1 - 4.9e-92 309.1 12.9 7.4e-92 308.5 12.9 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tim17 PF02466.19 PXF42548.1 - 6.2e-09 36.2 2.9 1.3e-08 35.2 2.9 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family KH_1 PF00013.29 PXF42549.1 - 8.9e-07 28.6 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 PXF42549.1 - 0.0081 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 PXF42550.1 - 1.1e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 KH domain RskA PF10099.9 PXF42550.1 - 0.01 16.1 10.8 0.02 15.2 1.2 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA GLTP PF08718.11 PXF42551.1 - 3.4e-35 121.5 0.3 5.7e-35 120.8 0.3 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Lig_chan PF00060.26 PXF42552.1 - 3.1 7.6 13.7 5.8 6.7 13.7 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel THOC7 PF05615.13 PXF42553.1 - 0.0034 17.7 3.6 0.0034 17.7 3.6 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 APH_6_hur PF04655.14 PXF42553.1 - 0.0064 15.9 0.3 0.0091 15.4 0.3 1.4 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Peptidase_C98 PF15499.6 PXF42553.1 - 0.024 14.1 0.7 0.032 13.7 0.7 1.3 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1664 PF07889.12 PXF42553.1 - 0.042 13.9 4.4 0.075 13.1 0.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 PXF42553.1 - 0.068 13.4 6.3 0.11 12.7 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MerR-DNA-bind PF09278.11 PXF42553.1 - 0.078 13.5 0.4 0.078 13.5 0.4 3.5 3 1 1 4 4 4 0 MerR, DNA binding Fib_alpha PF08702.10 PXF42553.1 - 0.31 11.2 5.4 6.5 6.9 1.5 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 PXF42553.1 - 0.77 9.8 4.4 9.5 6.3 0.1 2.6 3 0 0 3 3 3 0 FlxA-like protein WD40 PF00400.32 PXF42554.1 - 9.7e-12 45.2 20.6 9.3e-06 26.3 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Fez1 PF06818.15 PXF42554.1 - 0.02 15.3 1.4 0.031 14.7 1.4 1.2 1 0 0 1 1 1 0 Fez1 Cupin_1 PF00190.22 PXF42554.1 - 0.029 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF641 PF04859.12 PXF42554.1 - 0.056 13.8 2.1 0.067 13.5 1.0 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) EF_TS PF00889.19 PXF42554.1 - 0.065 12.8 1.2 0.11 12.1 1.2 1.2 1 0 0 1 1 1 0 Elongation factor TS APG6_N PF17675.1 PXF42554.1 - 0.12 12.9 5.2 0.19 12.2 5.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region BST2 PF16716.5 PXF42554.1 - 0.22 12.1 2.7 0.42 11.2 2.7 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 PXF42554.1 - 0.28 10.0 5.6 0.44 9.4 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 PXF42554.1 - 0.42 10.7 2.4 0.65 10.1 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 PXF42554.1 - 0.68 10.1 5.3 1.1 9.4 5.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PGI PF00342.19 PXF42555.1 - 3.9e-194 645.8 0.0 4.6e-194 645.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF167 PF02594.16 PXF42556.1 - 0.042 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 PGM_PMM_I PF02878.16 PXF42557.1 - 1.7e-23 82.8 0.0 3.3e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PXF42557.1 - 6.2e-20 71.7 0.1 1.3e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PXF42557.1 - 2e-13 50.5 0.0 5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PP2C PF00481.21 PXF42558.1 - 3.6e-08 33.3 0.2 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PXF42558.1 - 3.4e-06 27.1 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PXF42558.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C RskA PF10099.9 PXF42558.1 - 0.0051 17.1 5.3 0.012 16.0 5.3 1.6 1 0 0 1 1 1 1 Anti-sigma-K factor rskA GGACT PF06094.12 PXF42559.1 - 1.5e-21 77.2 0.1 2.1e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PXF42559.1 - 1.9e-05 25.0 0.5 0.0022 18.3 0.1 2.6 2 1 0 2 2 2 2 AIG2-like family ORC6 PF05460.13 PXF42559.1 - 4.2 6.5 7.6 5.9 6.1 7.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_9_N PF15420.6 PXF42560.1 - 0.038 14.0 1.2 0.13 12.2 1.2 1.8 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus RMI2 PF16100.5 PXF42561.1 - 6.2e-14 51.9 0.0 7.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 PXF42561.1 - 0.0047 16.9 0.2 0.0076 16.2 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HupF_HypC PF01455.18 PXF42561.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 HupF/HypC family UQ_con PF00179.26 PXF42562.1 - 1.2e-26 93.1 0.0 2.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PXF42562.1 - 0.00027 20.8 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain zf-C3HC4 PF00097.25 PXF42562.1 - 0.32 10.9 1.9 0.86 9.5 1.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PXF42563.1 - 5.4e-33 114.2 0.2 8.1e-33 113.6 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF42563.1 - 1.5e-13 51.1 0.1 3.9e-13 49.7 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF42563.1 - 2.3e-07 31.0 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PXF42563.1 - 4.8e-06 25.5 0.0 8.4e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 PXF42563.1 - 2.5e-05 24.6 0.0 0.00028 21.2 0.0 2.5 2 1 0 3 3 3 1 AAA domain IucA_IucC PF04183.12 PXF42564.1 - 0.016 14.8 0.2 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 IucA / IucC family PDH PF02153.17 PXF42564.1 - 0.028 13.4 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase RCC1_2 PF13540.6 PXF42565.1 - 3.4e-30 103.2 29.1 3.4e-07 29.9 0.1 8.1 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 PXF42565.1 - 1.4e-26 92.8 17.9 1.2e-05 25.8 0.3 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat TraB PF01963.17 PXF42566.1 - 4.8e-08 33.2 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 2 TraB family NAD_binding_10 PF13460.6 PXF42567.1 - 1.1e-25 90.6 0.0 1.3e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PXF42567.1 - 2e-05 24.2 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF42567.1 - 0.0073 15.3 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 PXF42567.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family PAC2 PF09754.9 PXF42567.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 PAC2 family GLE1 PF07817.13 PXF42568.1 - 1.2e-49 168.8 0.1 1.8e-49 168.2 0.1 1.2 1 0 0 1 1 1 1 GLE1-like protein Nup84_Nup100 PF04121.13 PXF42569.1 - 3.4e-66 223.8 3.8 1.4e-32 112.7 0.9 2.0 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF2225 PF09986.9 PXF42569.1 - 0.19 11.4 1.0 0.33 10.6 0.4 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Hat1_N PF10394.9 PXF42570.1 - 3.1e-14 53.5 0.0 5.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 PXF42570.1 - 0.007 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF42570.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHO4 PF01384.20 PXF42572.1 - 2.9e-119 398.0 12.3 4.3e-119 397.5 12.3 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF4199 PF13858.6 PXF42572.1 - 0.0071 16.8 1.0 0.0071 16.8 1.0 4.1 3 2 0 3 3 3 1 Protein of unknown function (DUF4199) HTH_IclR PF09339.10 PXF42572.1 - 0.051 13.4 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain LapA_dom PF06305.11 PXF42572.1 - 0.13 12.1 0.2 0.13 12.1 0.2 5.4 6 1 0 6 6 6 0 Lipopolysaccharide assembly protein A domain TRAP_alpha PF03896.16 PXF42574.1 - 4.5e-23 81.8 4.7 1.1e-22 80.6 4.7 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit CcmH PF03918.14 PXF42574.1 - 0.034 13.4 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF5385 PF17359.2 PXF42574.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Calc_CGRP_IAPP PF00214.19 PXF42574.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family CbtB PF09489.10 PXF42574.1 - 4 7.6 6.0 16 5.7 0.5 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) LsmAD PF06741.13 PXF42574.1 - 9.3 6.9 11.4 5.3 7.7 8.3 2.1 2 0 0 2 2 2 0 LsmAD domain PhrC_PhrF PF11131.8 PXF42574.1 - 9.5 5.9 6.9 0.82 9.3 0.3 2.5 3 0 0 3 3 3 0 Rap-phr extracellular signalling SRAP PF02586.14 PXF42575.1 - 6.3e-39 133.8 0.1 8.7e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) DDE_1 PF03184.19 PXF42576.1 - 1.3e-11 44.4 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PcfK PF14058.6 PXF42576.1 - 0.17 12.1 1.8 14 6.0 0.3 2.8 3 0 0 3 3 3 0 PcfK-like protein PilS PF08805.11 PXF42579.1 - 0.024 14.4 0.5 0.024 14.4 0.5 2.0 2 0 0 2 2 2 0 PilS N terminal Pentapeptide_2 PF01469.18 PXF42581.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Peptidase_S8 PF00082.22 PXF42582.1 - 2.5e-05 23.7 0.3 0.00011 21.5 0.3 2.0 1 1 0 1 1 1 1 Subtilase family zf-C2HC_2 PF13913.6 PXF42585.1 - 0.00027 20.7 0.6 0.00027 20.7 0.6 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PXF42585.1 - 0.07 13.6 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42585.1 - 0.13 13.1 0.3 0.39 11.7 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger CitMHS PF03600.16 PXF42587.1 - 2.6e-08 33.4 8.2 3.7e-08 32.9 8.2 1.2 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 PXF42587.1 - 0.003 16.7 5.9 0.0037 16.4 5.9 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region FUSC-like PF12805.7 PXF42587.1 - 0.13 11.3 4.6 0.3 10.1 4.6 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS FliL PF03748.14 PXF42588.1 - 0.00063 20.3 0.3 0.00099 19.7 0.3 1.3 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL MFS_1 PF07690.16 PXF42591.1 - 1e-45 156.2 33.8 1e-45 156.2 33.8 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily DnaJ_CXXCXGXG PF00684.19 PXF42591.1 - 0.024 15.0 4.1 0.053 13.9 4.1 1.5 1 1 0 1 1 1 0 DnaJ central domain DUF1356 PF07092.12 PXF42591.1 - 0.29 10.4 0.8 0.62 9.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF5351 PF17302.2 PXF42591.1 - 2.2 8.5 10.7 1.5 9.1 2.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 PXF42591.1 - 9.8 6.2 7.8 2.9e+02 1.5 7.8 2.3 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein SPT16 PF08644.11 PXF42592.1 - 3.5e-44 150.6 0.0 3.5e-44 150.6 0.0 2.6 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 PXF42592.1 - 1.6e-28 99.8 0.0 2.6e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.6 PXF42592.1 - 1.6e-16 60.6 0.0 1.8e-15 57.1 0.0 2.4 1 1 1 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 PXF42592.1 - 2.1e-14 53.7 0.1 5.7e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Holin_BlyA PF05102.12 PXF42595.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.0 2 0 0 2 2 2 0 holin, BlyA family adh_short PF00106.25 PXF42598.1 - 1.1e-27 96.8 0.0 1.5e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF42598.1 - 4.8e-22 78.7 0.0 6.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF42598.1 - 1.5e-06 28.2 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF42598.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 PXF42598.1 - 0.046 13.5 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sacchrp_dh_NADP PF03435.18 PXF42598.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Hint PF01079.20 PXF42601.1 - 4.2e-29 101.6 0.0 8.5e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Hint module Cu2_monooxygen PF01082.20 PXF42601.1 - 6.2e-21 75.0 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 PXF42601.1 - 8.6e-21 74.1 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 PXF42601.1 - 6.1e-07 29.7 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 DOMON domain Hom_end_hint PF05203.16 PXF42601.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Hom_end-associated Hint F-protein PF00469.20 PXF42601.1 - 0.19 11.3 0.6 0.33 10.5 0.6 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CENP-B_dimeris PF09026.10 PXF42601.1 - 0.84 10.1 13.7 2.1 8.8 13.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDE_Tnp_4 PF13359.6 PXF42602.1 - 2.4e-09 37.1 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Spond_N PF06468.13 PXF42603.1 - 9.3e-09 35.7 0.0 1.1e-08 35.5 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Acetyltransf_10 PF13673.7 PXF42604.1 - 8.7e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF42604.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF42604.1 - 0.00018 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hint PF01079.20 PXF42605.1 - 2.4e-28 99.1 0.0 5.3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Hint module Cu2_monoox_C PF03712.15 PXF42605.1 - 1.9e-22 79.4 0.2 3.8e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PXF42605.1 - 4.5e-21 75.4 0.0 1.1e-20 74.2 0.0 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 PXF42605.1 - 6.4e-08 32.9 0.0 1.9e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 DOMON domain Hom_end_hint PF05203.16 PXF42605.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint F-protein PF00469.20 PXF42605.1 - 0.16 11.6 0.6 0.33 10.5 0.6 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CENP-B_dimeris PF09026.10 PXF42605.1 - 0.79 10.1 13.7 2.1 8.8 13.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Biotin_carb_N PF00289.22 PXF42606.1 - 2.1e-24 86.2 0.0 2.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain GxGYxYP_N PF16216.5 PXF42606.1 - 0.045 13.9 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_carb_C PF02785.19 PXF42607.1 - 1.2e-19 70.4 0.0 1.8e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain DUF4218 PF13960.6 PXF42611.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) AKAP_110 PF05716.13 PXF42611.1 - 0.1 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Vps55 PF04133.14 PXF42614.1 - 0.05 13.6 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DUF563 PF04577.14 PXF42615.1 - 6.4e-18 65.7 0.1 1.3e-17 64.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF2000 PF09391.10 PXF42616.1 - 0.061 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Sel1 PF08238.12 PXF42617.1 - 3e-63 208.8 0.3 1e-05 26.0 0.0 12.1 12 0 0 12 12 12 10 Sel1 repeat TPR_6 PF13174.6 PXF42617.1 - 6.5e-06 26.5 11.4 6 7.7 0.0 9.6 11 1 0 11 11 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF42617.1 - 3.9e-05 24.1 20.2 11 7.1 0.2 9.1 6 1 4 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF42617.1 - 6.3e-05 23.5 13.6 0.52 11.0 0.0 6.9 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42617.1 - 0.00023 20.9 10.6 7.8 6.8 0.1 8.1 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF42617.1 - 0.00026 20.7 5.0 16 5.5 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 PXF42617.1 - 0.00045 20.4 5.2 0.25 11.6 0.1 5.5 5 2 1 6 6 5 1 Tetratrico peptide repeat TPR_17 PF13431.6 PXF42617.1 - 0.0015 18.8 0.3 92 3.8 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42617.1 - 0.02 15.0 14.9 47 4.4 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42617.1 - 0.062 13.5 8.2 34 5.0 0.0 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat HEPN_Apea PF18739.1 PXF42617.1 - 0.12 12.8 0.0 1.1e+02 3.3 0.0 4.2 5 1 1 6 6 6 0 Apea-like HEPN TPR_11 PF13414.6 PXF42617.1 - 3.8 7.3 7.9 23 4.7 0.2 4.9 5 0 0 5 5 5 0 TPR repeat PRAS PF15798.5 PXF42620.1 - 0.19 12.3 3.4 0.15 12.6 0.8 1.9 1 1 1 2 2 2 0 Proline-rich AKT1 substrate 1 ATP-synt_I PF03899.15 PXF42621.1 - 0.0014 18.9 4.6 0.0022 18.3 4.6 1.2 1 0 0 1 1 1 1 ATP synthase I chain AtpR PF12966.7 PXF42621.1 - 0.018 15.4 1.0 0.034 14.6 1.0 1.4 1 0 0 1 1 1 0 N-ATPase, AtpR subunit TPT PF03151.16 PXF42622.1 - 6.1e-48 163.6 21.6 1.1e-47 162.8 21.6 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF42622.1 - 3e-11 43.6 33.4 2.1e-05 24.7 14.9 2.4 2 1 0 2 2 2 2 EamA-like transporter family WD40 PF00400.32 PXF42623.1 - 1.6e-06 28.7 3.6 0.36 11.8 0.6 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 PXF42623.1 - 0.00024 21.5 3.3 0.0036 17.7 0.0 4.2 5 1 1 6 6 6 1 PQQ-like domain PQQ_2 PF13360.6 PXF42623.1 - 0.0011 18.6 0.3 0.0065 16.1 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 PXF42623.1 - 0.071 13.1 0.4 20 5.3 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat Glyco_transf_90 PF05686.12 PXF42624.1 - 1.3e-20 73.7 4.0 8.4e-19 67.7 3.5 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 EKR PF10371.9 PXF42624.1 - 0.12 12.2 0.1 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function PTCB-BRCT PF12738.7 PXF42625.1 - 4.1e-43 145.1 5.9 8.7e-17 60.8 0.1 4.4 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 PXF42625.1 - 3.5e-32 110.6 0.4 1.5e-08 34.9 0.0 5.6 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PXF42625.1 - 3.7e-18 65.7 0.1 0.059 13.8 0.0 5.3 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 PXF42625.1 - 9.7e-05 22.4 1.5 0.12 12.4 0.0 3.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 PXF42625.1 - 0.00027 20.8 0.0 0.53 10.2 0.0 4.1 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 PXF42625.1 - 0.00076 19.7 5.8 0.17 12.2 0.1 4.5 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain Abhydrolase_6 PF12697.7 PXF42626.1 - 6.3e-21 76.0 0.5 8.1e-21 75.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF42626.1 - 1.5e-20 73.5 0.0 9e-20 71.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF42626.1 - 5.8e-14 52.4 0.0 3.4e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 PXF42626.1 - 2.2e-09 37.4 0.1 0.00017 21.5 0.1 2.3 2 0 0 2 2 2 2 Serine hydrolase FSH1 PF03959.13 PXF42626.1 - 0.0025 17.5 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF3530 PF12048.8 PXF42626.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 PXF42626.1 - 0.016 15.0 0.1 0.31 10.8 0.1 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 PXF42626.1 - 0.023 14.3 0.0 0.034 13.7 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 PXF42626.1 - 0.035 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.21 PXF42626.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PXF42626.1 - 0.16 11.8 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Topo-VIb_trans PF09239.11 PXF42627.1 - 3.8e-51 173.1 0.0 7.5e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 PXF42627.1 - 9.8e-07 28.7 0.0 2.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PXF42627.1 - 3.3e-05 24.3 0.0 0.00011 22.7 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mtr2 PF10429.9 PXF42627.1 - 0.043 13.8 0.1 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 RPA_C PF08784.11 PXF42628.1 - 1.4e-12 48.2 1.6 1.4e-12 48.2 1.6 2.2 2 0 0 2 2 2 1 Replication protein A C terminal SUIM_assoc PF16619.5 PXF42628.1 - 0.015 15.4 2.8 0.028 14.5 2.8 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PXF42628.1 - 0.077 12.6 4.9 0.1 12.2 4.9 1.2 1 0 0 1 1 1 0 Spt20 family Atx10homo_assoc PF09759.9 PXF42630.1 - 0.0049 16.9 1.6 0.031 14.3 0.3 2.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF948 PF06103.11 PXF42630.1 - 0.023 14.9 3.5 7.2 6.9 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PXF42630.1 - 0.055 12.3 12.5 0.25 10.2 5.7 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 PXF42630.1 - 0.073 13.6 15.5 0.84 10.2 3.0 3.7 2 2 2 4 4 4 0 Spectrin repeat ROS_MUCR PF05443.11 PXF42630.1 - 0.12 12.4 1.4 0.19 11.7 0.1 2.0 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DHR10 PF18595.1 PXF42630.1 - 0.18 11.8 17.5 2.6 8.2 3.1 3.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Hemerythrin PF01814.23 PXF42630.1 - 0.43 11.2 7.5 3.3 8.3 0.2 3.6 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF724 PF05266.14 PXF42630.1 - 0.53 10.1 8.4 0.23 11.3 2.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) WXG100 PF06013.12 PXF42630.1 - 0.81 10.0 6.7 11 6.3 0.4 3.5 4 0 0 4 4 4 0 Proteins of 100 residues with WXG HR1 PF02185.16 PXF42630.1 - 1.2 9.3 6.6 19 5.5 0.1 3.5 3 0 0 3 3 3 0 Hr1 repeat DUF16 PF01519.16 PXF42630.1 - 1.5 9.3 6.2 6.8 7.2 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 PXF42630.1 - 6.2 7.3 11.1 59 4.2 1.8 4.3 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4226 PF10774.9 PXF42630.1 - 8.9 6.6 9.4 2.5 8.4 0.3 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4226) IPPT PF01715.17 PXF42631.1 - 8.7e-51 172.9 0.0 2e-49 168.4 0.0 2.3 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 PXF42631.1 - 7.4e-08 32.1 0.0 3.2e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Isopentenyl transferase DUF349 PF03993.12 PXF42631.1 - 0.25 11.6 3.8 0.26 11.6 0.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Myb_DNA-binding PF00249.31 PXF42633.1 - 5e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain NAD_binding_10 PF13460.6 PXF42634.1 - 2.3e-27 96.1 0.0 2.5e-26 92.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF42634.1 - 1.7e-09 37.6 0.0 5.8e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 PXF42634.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PXF42634.1 - 0.00028 20.1 0.0 0.017 14.3 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 PXF42634.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 PXF42634.1 - 0.0017 17.8 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PXF42634.1 - 0.0023 17.1 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 PXF42634.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 PXF42634.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PXF42634.1 - 0.054 12.6 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1294 PF06961.13 PXF42636.1 - 2e-20 72.8 0.2 3e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) Mpv17_PMP22 PF04117.12 PXF42636.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Mpv17 / PMP22 family NrfD PF03916.14 PXF42636.1 - 0.036 13.7 0.2 0.038 13.6 0.2 1.2 1 0 0 1 1 1 0 Polysulphide reductase, NrfD DUF1298 PF06974.13 PXF42636.1 - 0.25 11.3 1.5 0.36 10.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) TH1 PF04858.13 PXF42637.1 - 5.6e-19 68.2 5.3 1.9e-09 36.8 0.2 2.1 2 0 0 2 2 2 2 TH1 protein SIP1 PF04938.12 PXF42637.1 - 0.012 15.3 0.1 0.09 12.5 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) LLGL PF08366.13 PXF42637.1 - 0.017 15.5 0.1 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 LLGL2 PPIP5K2_N PF18086.1 PXF42638.1 - 3.5e-21 75.2 0.0 5.3e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 PXF42638.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2237 PF09996.9 PXF42639.1 - 3.1e-52 175.4 0.1 4.2e-52 175.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) AMPK1_CBM PF16561.5 PXF42640.1 - 9.7e-26 89.8 0.1 1.5e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 PXF42640.1 - 0.0095 16.3 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF908 PF06012.12 PXF42640.1 - 8.5 5.7 7.7 10 5.4 7.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Esterase_phd PF10503.9 PXF42641.1 - 0.00014 21.4 0.1 0.00023 20.7 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 PXF42641.1 - 0.0039 17.1 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 PXF42641.1 - 0.0068 16.1 0.0 0.0083 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 PXF42641.1 - 0.0096 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 PXF42641.1 - 0.033 13.7 0.0 0.053 13.1 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PXF42641.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family HTH_Crp_2 PF13545.6 PXF42641.1 - 0.094 12.7 0.0 1.5 8.9 0.0 2.2 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Abhydrolase_2 PF02230.16 PXF42641.1 - 0.13 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 PXF42641.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Uma2 PF05685.12 PXF42643.1 - 2.2e-07 30.6 0.3 1.5e-06 27.9 0.3 2.2 1 1 0 1 1 1 1 Putative restriction endonuclease Borrelia_P83 PF05262.11 PXF42643.1 - 0.013 14.0 43.6 0.017 13.6 43.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TMEM171 PF15471.6 PXF42643.1 - 0.16 11.0 0.5 1.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Transmembrane protein family 171 SLC12 PF03522.15 PXF42643.1 - 1.2 8.0 28.8 2.9 6.8 28.8 1.7 1 0 0 1 1 1 0 Solute carrier family 12 CDC27 PF09507.10 PXF42643.1 - 1.5 8.1 61.4 14 4.9 59.6 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Uma2 PF05685.12 PXF42646.1 - 1.3e-07 31.3 0.4 8.8e-07 28.6 0.4 2.2 1 1 0 1 1 1 1 Putative restriction endonuclease TMEM171 PF15471.6 PXF42646.1 - 0.2 10.6 0.7 2.5 7.0 0.0 2.8 2 0 0 2 2 2 0 Transmembrane protein family 171 CorA PF01544.18 PXF42647.1 - 1.6e-06 27.7 5.4 5.1e-06 26.0 5.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PXF42647.1 - 0.036 14.1 3.2 2.1 8.4 0.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_S27 PF01599.19 PXF42649.1 - 1.5e-25 89.0 1.4 1.5e-25 89.0 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 PXF42649.1 - 0.016 14.9 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family IBR PF01485.21 PXF42649.1 - 0.023 14.9 0.3 0.034 14.4 0.3 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Peptidase_S8 PF00082.22 PXF42650.1 - 6.9e-68 229.1 0.0 8.9e-67 225.4 0.0 2.3 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.8 PXF42650.1 - 4.7e-40 137.1 0.0 1.3e-39 135.7 0.0 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II Glyco_transf_90 PF05686.12 PXF42651.1 - 1.4e-25 90.1 1.3 4.4e-25 88.4 1.3 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 RT_RNaseH PF17917.1 PXF42651.1 - 0.076 13.3 0.5 1.4 9.3 0.2 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Tim17 PF02466.19 PXF42652.1 - 7.3e-14 52.1 6.4 1.2e-13 51.4 6.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ADH_zinc_N PF00107.26 PXF42653.1 - 3.8e-22 78.7 0.0 5.4e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 PXF42653.1 - 0.023 15.0 0.1 0.036 14.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Alpha-amylase_C PF02806.18 PXF42654.1 - 2.1e-18 66.6 0.7 9e-18 64.6 0.5 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 PXF42654.1 - 4.4e-15 55.8 0.2 1.9e-14 53.8 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PXF42654.1 - 1.2e-11 44.8 0.5 1.2e-11 44.8 0.5 2.2 2 1 1 3 3 3 1 Alpha amylase, catalytic domain Lactamase_B PF00753.27 PXF42655.1 - 1.2e-11 45.0 0.0 3.6e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF42655.1 - 3.1e-05 23.6 0.0 6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPT PF03151.16 PXF42656.1 - 1.1e-23 84.0 11.4 2.3e-23 83.0 11.4 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF42656.1 - 1.3e-06 28.6 26.4 9.4e-05 22.6 11.1 2.7 3 0 0 3 3 3 2 EamA-like transporter family PS_pyruv_trans PF04230.13 PXF42656.1 - 2.5e-06 27.7 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase EmrE PF13536.6 PXF42656.1 - 3.2e-05 23.7 3.0 7.2e-05 22.5 3.0 1.6 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter Abhydrolase_2 PF02230.16 PXF42657.1 - 0.058 13.2 0.1 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 PXF42657.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Methyltransf_11 PF08241.12 PXF42658.1 - 3.5e-07 30.8 0.0 7.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF42658.1 - 4.2e-06 26.7 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF42658.1 - 0.0042 16.9 0.1 0.072 12.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF42658.1 - 0.016 15.9 0.0 0.054 14.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 PXF42658.1 - 0.04 12.8 0.0 0.07 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 PXF42658.1 - 0.095 12.4 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HMA PF00403.26 PXF42659.1 - 5.7e-52 174.0 1.4 6.2e-13 49.0 0.0 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 PXF42659.1 - 1.8e-48 164.5 0.8 1.8e-48 164.5 0.8 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PXF42659.1 - 8.8e-32 111.1 0.8 8.8e-32 111.1 0.8 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF42659.1 - 0.0093 16.4 0.1 0.043 14.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF42659.1 - 0.014 15.2 1.0 0.014 15.2 1.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TusA PF01206.17 PXF42659.1 - 0.15 11.9 0.1 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Sulfurtransferase TusA NAD2 PF18782.1 PXF42659.1 - 0.22 11.6 0.0 13 5.9 0.0 2.9 4 0 0 4 4 4 0 Novel AID APOBEC clade 2 I_LWEQ PF01608.17 PXF42659.1 - 1.3 9.3 4.3 1.3 9.3 0.7 2.4 2 0 0 2 2 2 0 I/LWEQ domain Fer2_BFD PF04324.15 PXF42659.1 - 2.2 8.7 4.3 71 3.9 0.2 3.9 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain HMA PF00403.26 PXF42660.1 - 5.2e-08 33.2 0.6 2.5e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain TALPID3 PF15324.6 PXF42663.1 - 0.04 11.6 3.8 0.044 11.5 3.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Epimerase PF01370.21 PXF42666.1 - 1.9e-25 89.8 0.0 2.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF42666.1 - 5.3e-18 65.0 0.0 6.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PXF42666.1 - 2e-12 47.2 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PXF42666.1 - 1.3e-11 44.7 0.0 4e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PXF42666.1 - 1.7e-10 40.6 0.5 5.5e-09 35.6 0.1 2.8 2 2 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.15 PXF42666.1 - 0.13 11.4 0.1 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 PXF42666.1 - 0.16 11.5 0.1 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family UPF0086 PF01868.16 PXF42667.1 - 2.4e-20 72.2 0.1 3.9e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 T4BSS_DotI_IcmL PF11393.8 PXF42669.1 - 0.15 11.6 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component PALP PF00291.25 PXF42670.1 - 2.9e-51 174.6 0.1 3.9e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TPR_1 PF00515.28 PXF42671.1 - 1.5e-43 144.9 17.2 6.6e-09 35.2 0.2 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 PXF42671.1 - 5.4e-35 116.7 13.6 1.2e-06 28.1 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat STI1 PF17830.1 PXF42671.1 - 3.8e-32 110.0 11.6 4.7e-17 61.7 0.0 3.9 5 0 0 5 5 5 2 STI1 domain TPR_11 PF13414.6 PXF42671.1 - 9.4e-24 82.8 6.6 5.6e-09 35.5 0.1 5.5 4 1 1 5 5 5 4 TPR repeat TPR_17 PF13431.6 PXF42671.1 - 6.8e-20 70.0 3.7 4.5e-05 23.5 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42671.1 - 3.3e-19 67.4 11.3 7.9e-05 22.6 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42671.1 - 9.2e-16 57.9 2.2 0.0001 22.5 0.1 5.3 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42671.1 - 1.2e-15 56.3 0.1 0.0014 18.5 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PXF42671.1 - 3.6e-15 55.4 0.4 0.1 13.5 0.0 6.6 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PXF42671.1 - 2.3e-14 53.7 0.6 0.00011 22.7 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 PXF42671.1 - 3.8e-13 49.7 3.6 0.0022 18.5 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PXF42671.1 - 1.3e-10 41.2 0.0 0.001 19.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PXF42671.1 - 3.1e-06 27.2 3.3 0.0038 17.3 0.0 3.8 4 0 0 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 PXF42671.1 - 3.5e-06 26.7 1.8 0.28 11.1 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF42671.1 - 4.6e-05 23.8 5.4 0.23 12.1 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 PXF42671.1 - 0.001 18.5 0.1 10 5.7 0.0 5.1 5 0 0 5 5 5 0 SHNi-TPR TPR_15 PF13429.6 PXF42671.1 - 0.0074 15.5 0.0 2.9 7.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 PXF42671.1 - 0.012 15.9 0.4 6.7 7.1 0.0 3.6 4 1 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF42671.1 - 0.021 15.0 2.5 0.25 11.6 0.3 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF357 PF04010.13 PXF42671.1 - 0.042 13.9 0.3 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF3856 PF12968.7 PXF42671.1 - 0.096 12.8 0.3 4.6 7.3 0.0 3.0 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) GerD PF17898.1 PXF42671.1 - 0.12 12.3 7.7 1.2 9.1 3.4 3.6 3 1 0 3 3 3 0 Spore germination GerD central core domain MIT PF04212.18 PXF42671.1 - 0.19 11.8 7.8 52 4.0 0.1 5.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Thioredoxin_4 PF13462.6 PXF42671.1 - 0.81 9.8 4.0 0.36 11.0 0.7 2.1 2 1 1 3 3 3 0 Thioredoxin GRDP-like PF07173.12 PXF42672.1 - 9.6e-24 84.7 11.3 5.7e-17 62.7 2.2 4.3 3 1 1 4 4 4 3 Glycine-rich domain-containing protein-like Nup96 PF12110.8 PXF42673.1 - 9.4e-26 90.6 0.0 3.3e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 Nuclear protein 96 PT PF04886.12 PXF42673.1 - 0.23 11.0 3.6 0.53 9.9 3.6 1.5 1 0 0 1 1 1 0 PT repeat Motile_Sperm PF00635.26 PXF42674.1 - 2.3e-19 69.2 0.0 3.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PKcGMP_CC PF16808.5 PXF42674.1 - 0.037 13.9 0.9 0.065 13.1 0.9 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4201 PF13870.6 PXF42674.1 - 0.04 13.7 0.3 0.059 13.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Asp PF00026.23 PXF42676.1 - 1.6e-42 146.1 0.0 1.2e-41 143.2 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PXF42676.1 - 2.1e-16 60.7 6.2 2.1e-16 60.7 6.2 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 PXF42676.1 - 1.7e-13 50.7 0.0 2.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 PXF42676.1 - 2.5e-06 27.9 0.1 0.012 16.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PXF42676.1 - 8.1e-05 23.2 0.0 0.29 11.8 0.0 3.1 3 0 0 3 3 3 2 Aspartyl protease Nuc_sug_transp PF04142.15 PXF42677.1 - 2.4e-24 86.1 20.8 3.3e-24 85.6 20.8 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PXF42677.1 - 8.5e-05 22.7 19.6 0.0032 17.6 7.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PXF42677.1 - 0.04 13.1 13.0 0.074 12.3 12.8 1.6 1 1 0 1 1 1 0 UAA transporter family DUF543 PF04418.12 PXF42677.1 - 1 9.4 4.2 0.48 10.4 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Citrate_synt PF00285.21 PXF42679.1 - 2.1e-116 388.9 0.0 2.5e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain RNA_pol_Rpb1_5 PF04998.17 PXF42681.1 - 6.1e-16 58.7 0.0 7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 MutS_V PF00488.21 PXF42683.1 - 1.2e-21 77.6 0.1 1e-20 74.6 0.1 1.9 1 1 0 1 1 1 1 MutS domain V PBS_linker_poly PF00427.21 PXF42685.1 - 2.4e-40 137.5 0.0 3.2e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide TetR PF13972.6 PXF42685.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Bacterial transcriptional repressor DUF1139 PF06599.11 PXF42686.1 - 0.058 12.8 0.1 0.062 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) LBR_tudor PF09465.10 PXF42687.1 - 0.00056 19.7 1.8 0.0014 18.4 1.8 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF4603 PF15376.6 PXF42687.1 - 0.0059 14.1 1.8 0.45 7.8 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4603) Orthopox_B11R PF07033.11 PXF42687.1 - 0.019 14.7 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Metallophos PF00149.28 PXF42689.1 - 1.7e-07 32.0 0.9 2.6e-07 31.3 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EFP PF01132.20 PXF42689.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain WDCP PF15390.6 PXF42692.1 - 9.1 4.5 11.1 11 4.3 11.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family WD40 PF00400.32 PXF42693.1 - 6.3e-07 30.0 0.3 0.013 16.3 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Anticodon_1 PF08264.13 PXF42694.1 - 0.0062 16.5 0.0 0.0085 16.1 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 PXF42695.1 - 1.7e-19 69.6 0.0 2e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) WD40 PF00400.32 PXF42698.1 - 5.5e-33 112.5 22.3 1.1e-05 26.1 0.0 10.0 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42698.1 - 1.4e-14 54.2 7.1 0.031 14.6 0.0 7.6 4 4 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF42698.1 - 5.6e-14 51.9 0.0 9.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 PXF42698.1 - 2e-05 23.7 1.1 2.5 7.0 0.0 5.5 4 2 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PXF42698.1 - 0.0003 20.7 2.2 7.4 6.6 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 PXF42698.1 - 0.063 12.4 4.2 6.3 5.8 0.0 4.3 3 1 1 5 5 5 0 Protein of unknown function (DUF1513) WD40_3 PF15911.5 PXF42698.1 - 0.065 13.3 0.1 0.41 10.7 0.0 2.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Hydrolase PF00702.26 PXF42701.1 - 5.2e-17 62.8 0.4 1.7e-15 57.9 0.4 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PXF42701.1 - 2.3e-12 46.8 0.0 5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 PXF42701.1 - 8.4e-06 25.6 1.0 8.4e-06 25.6 1.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PXF42701.1 - 8.8e-05 22.1 0.4 8.8e-05 22.1 0.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PXF42701.1 - 0.00096 19.0 0.3 0.046 13.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SAND PF01342.21 PXF42701.1 - 0.12 12.1 0.2 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 SAND domain HAD PF12710.7 PXF42701.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase STAG PF08514.11 PXF42702.1 - 2.4e-09 37.1 0.0 4.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 STAG domain Urease_gamma PF00547.18 PXF42702.1 - 0.049 13.9 0.1 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 Urease, gamma subunit WD40 PF00400.32 PXF42703.1 - 1.7e-39 133.1 31.5 3e-07 31.0 0.1 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42703.1 - 5.8e-16 58.6 3.3 0.00011 22.4 0.0 7.5 4 4 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF42703.1 - 8.4e-13 48.1 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Ge1_WD40 PF16529.5 PXF42703.1 - 1.1e-06 27.9 2.4 3.8 6.4 0.0 5.8 5 2 2 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 PXF42703.1 - 0.0013 17.6 0.0 1.4 7.6 0.0 3.1 3 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 PXF42703.1 - 0.009 14.7 1.4 0.15 10.7 0.1 3.0 2 1 1 4 4 4 1 Nucleoporin Nup120/160 DUF2252 PF10009.9 PXF42703.1 - 0.016 14.3 2.3 0.98 8.4 2.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Apolipoprotein PF01442.18 PXF42703.1 - 0.14 12.0 4.1 0.29 11.0 4.1 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PQQ_3 PF13570.6 PXF42703.1 - 0.36 11.4 16.9 2.7 8.6 0.1 6.4 6 1 1 7 7 7 0 PQQ-like domain DUF4164 PF13747.6 PXF42703.1 - 0.54 10.6 5.9 1.2 9.4 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Uma2 PF05685.12 PXF42714.1 - 0.00065 19.3 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Uma2 PF05685.12 PXF42715.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative restriction endonuclease Macoilin PF09726.9 PXF42715.1 - 0.057 12.0 8.9 0.069 11.7 8.9 1.0 1 0 0 1 1 1 0 Macoilin family Tho2 PF11262.8 PXF42715.1 - 0.11 11.7 6.0 0.14 11.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AAA_11 PF13086.6 PXF42715.1 - 0.12 12.2 4.9 0.13 12.0 4.9 1.1 1 0 0 1 1 1 0 AAA domain HemX PF04375.14 PXF42715.1 - 0.29 10.4 6.1 0.39 10.0 6.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CIAPIN1 PF05093.13 PXF42715.1 - 0.55 10.8 4.9 1.1 9.8 4.9 1.6 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Presenilin PF01080.17 PXF42715.1 - 6.3 5.5 8.7 7.9 5.1 8.7 1.0 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 PXF42717.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF42717.1 - 0.72 9.8 2.6 17 5.5 0.3 2.5 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 PXF42719.1 - 7.1e-07 28.8 0.0 2.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42719.1 - 2.1e-05 23.9 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 PXF42719.1 - 6.7e-05 22.6 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 PXF42719.1 - 0.00013 22.0 0.5 0.29 11.0 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF42719.1 - 0.0099 15.5 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PXF42719.1 - 0.069 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PMM PF03332.13 PXF42722.1 - 2.3e-103 344.7 0.5 2.6e-103 344.6 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PXF42722.1 - 6.6e-07 29.3 0.0 2.4e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF42722.1 - 2.1e-05 24.2 0.0 0.0056 16.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Uma2 PF05685.12 PXF42723.1 - 3e-12 46.4 0.4 2.3e-10 40.3 0.4 2.4 1 1 0 1 1 1 1 Putative restriction endonuclease DUF4597 PF15366.6 PXF42723.1 - 1.2 8.9 5.0 0.75 9.6 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) DUF4407 PF14362.6 PXF42723.1 - 3.8 6.8 21.4 5.8 6.2 21.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 PXF42723.1 - 4.1 7.1 18.6 6.8 6.4 18.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleoporin2 PF04096.14 PXF42724.1 - 2.3e-30 105.7 0.0 3.5e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase DUF1759 PF03564.15 PXF42726.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Aminotran_4 PF01063.19 PXF42726.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Amino-transferase class IV PPDK_N PF01326.19 PXF42728.1 - 3.3e-09 36.5 0.0 6.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PPDK_N PF01326.19 PXF42729.1 - 1.9e-37 129.3 1.2 1.7e-35 122.9 1.2 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain APH PF01636.23 PXF42731.1 - 6.2e-06 26.3 0.0 1.5e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF42731.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 PXF42736.1 - 6.5e-07 29.5 0.4 2.6e-06 27.5 0.3 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF42736.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PPDK_N PF01326.19 PXF42738.1 - 1.9e-37 129.3 1.2 1.7e-35 122.9 1.2 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PPDK_N PF01326.19 PXF42739.1 - 3.3e-09 36.5 0.0 6.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ubie_methyltran PF01209.18 PXF42741.1 - 5.9e-21 74.9 0.0 7.3e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family BRCA-2_helical PF09169.10 PXF42743.1 - 0.046 13.4 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 BRCA2, helical Chorismate_synt PF01264.21 PXF42743.1 - 0.089 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Chorismate synthase HSCB_C PF07743.13 PXF42743.1 - 0.21 12.1 7.9 1 9.9 0.9 3.0 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain BLOC1_2 PF10046.9 PXF42743.1 - 0.27 11.6 5.0 0.31 11.4 2.6 2.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MerR-DNA-bind PF09278.11 PXF42743.1 - 0.98 10.0 4.3 5.8 7.5 0.4 2.4 2 0 0 2 2 2 0 MerR, DNA binding Glutenin_hmw PF03157.13 PXF42744.1 - 0.017 13.6 2.8 0.019 13.4 2.8 1.3 1 0 0 1 1 1 0 High molecular weight glutenin subunit DUF3954 PF13128.6 PXF42745.1 - 0.014 15.2 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) ALC PF17527.2 PXF42745.1 - 0.034 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Phage ALC protein RNase_PH PF01138.21 PXF42747.1 - 0.0014 19.2 0.1 0.0032 18.0 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 THOC7 PF05615.13 PXF42749.1 - 0.002 18.4 1.3 0.0031 17.8 1.3 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 Chibby PF14645.6 PXF42749.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Chibby family ZapB PF06005.12 PXF42749.1 - 0.0082 16.6 3.3 0.011 16.1 3.3 1.3 1 0 0 1 1 1 1 Cell division protein ZapB HALZ PF02183.18 PXF42749.1 - 0.0088 16.2 0.5 0.0088 16.2 0.5 1.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper JIP_LZII PF16471.5 PXF42749.1 - 0.022 14.9 0.8 0.035 14.3 0.8 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PXF42749.1 - 0.029 14.5 1.5 0.052 13.7 1.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor APC_N_CC PF16689.5 PXF42749.1 - 0.05 13.7 0.5 0.089 12.9 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1664 PF07889.12 PXF42749.1 - 0.084 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 PXF42749.1 - 0.12 13.0 0.5 0.12 13.0 0.5 1.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF1843 PF08898.10 PXF42749.1 - 0.44 11.1 3.7 7.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DivIC PF04977.15 PXF42749.1 - 0.46 10.3 3.7 0.9 9.4 3.7 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF2205 PF10224.9 PXF42749.1 - 0.7 9.9 4.4 4.1 7.5 3.5 2.1 1 1 1 2 2 2 0 Short coiled-coil protein Ribosomal_L7Ae PF01248.26 PXF42750.1 - 7.1e-28 96.2 0.7 1e-27 95.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fcf1 PF04900.12 PXF42750.1 - 0.093 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Fcf1 Chloroa_b-bind PF00504.21 PXF42753.1 - 0.00035 21.1 0.1 0.098 13.2 0.0 1.3 1 1 1 2 2 2 2 Chlorophyll A-B binding protein WD40 PF00400.32 PXF42755.1 - 6.2e-13 49.0 14.5 1.1e-05 26.0 0.0 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42755.1 - 5.6e-08 33.0 0.7 0.098 13.0 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF42755.1 - 9.7e-05 21.5 0.1 0.13 11.2 0.1 2.9 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PE-PPE PF08237.11 PXF42755.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain C2 PF00168.30 PXF42756.1 - 1.1e-06 28.8 0.1 3.3e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 C2 domain Peptidase_C16 PF01831.17 PXF42761.1 - 0.015 15.0 0.1 0.016 15.0 0.1 1.0 1 0 0 1 1 1 0 Peptidase C16 family Cation_ATPase PF13246.6 PXF42763.1 - 3.1e-07 30.4 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF42764.1 - 0.00045 20.6 0.1 0.002 18.4 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase IGPS PF00218.21 PXF42765.1 - 1.7e-07 30.7 0.2 2.4e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase Lactamase_B_2 PF12706.7 PXF42770.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF42770.1 - 0.059 13.4 0.7 0.22 11.5 0.4 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ku PF02735.16 PXF42771.1 - 5.6e-24 85.0 0.0 1.2e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 PXF42771.1 - 1.1e-10 41.7 0.6 5e-10 39.6 0.1 2.3 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 PXF42771.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain DUF1168 PF06658.12 PXF42771.1 - 0.13 12.1 4.1 0.27 11.1 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF3306 PF11748.8 PXF42771.1 - 0.44 11.4 5.9 1.5 9.7 5.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Nup188 PF10487.9 PXF42774.1 - 5.4e-05 21.3 0.0 0.0004 18.4 0.0 1.9 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DAO PF01266.24 PXF42775.1 - 0.0025 17.4 0.1 0.069 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PXF42775.1 - 0.096 12.0 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pribosyltran_N PF13793.6 PXF42776.1 - 1.4e-49 166.9 1.6 4.5e-49 165.2 0.1 2.4 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PXF42776.1 - 6.2e-24 85.0 3.2 1.7e-23 83.6 0.8 2.4 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PXF42776.1 - 3.7e-22 78.5 2.9 6e-21 74.6 0.7 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PXF42776.1 - 6e-05 22.6 0.2 0.00011 21.7 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_12 PF13087.6 PXF42777.1 - 1.7e-55 187.8 0.0 2.6e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PXF42777.1 - 1.8e-52 178.8 1.8 5.7e-29 101.7 0.1 2.4 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 PXF42777.1 - 1.3e-45 155.1 6.1 3e-36 124.7 0.0 2.8 2 1 1 3 3 3 2 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 PXF42777.1 - 1e-23 83.4 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 PXF42777.1 - 1e-16 61.2 0.1 1.5e-15 57.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF42777.1 - 2e-11 44.4 0.1 4.5e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PXF42777.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PXF42777.1 - 0.00019 20.8 0.1 0.0027 17.0 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 PXF42777.1 - 0.00022 21.1 0.1 0.00053 19.9 0.1 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 PXF42777.1 - 0.00054 19.6 0.0 0.066 12.7 0.1 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 PXF42777.1 - 0.003 18.0 0.3 0.0097 16.3 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 PXF42777.1 - 0.0041 16.3 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 PXF42777.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 PXF42777.1 - 0.042 13.6 0.3 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 PXF42777.1 - 0.042 13.5 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 PXF42777.1 - 0.057 13.7 0.1 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 PXF42777.1 - 0.065 13.0 0.4 0.12 12.1 0.4 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 PXF42777.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 PXF42777.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 PXF42777.1 - 0.18 12.3 0.1 0.46 10.9 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TLD PF07534.16 PXF42778.1 - 0.00013 22.2 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 TLD MMR_HSR1 PF01926.23 PXF42779.1 - 3.6e-20 72.1 0.0 5.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PXF42779.1 - 1.1e-08 34.9 0.0 1.2e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PXF42779.1 - 3.8e-08 33.0 0.0 6.4e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B KH_2 PF07650.17 PXF42779.1 - 1.6e-06 27.9 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KH domain RsgA_GTPase PF03193.16 PXF42779.1 - 1.9e-05 24.6 0.0 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PXF42779.1 - 0.00033 20.8 0.4 0.0023 18.0 0.3 2.1 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 PXF42779.1 - 0.00056 20.1 0.0 0.0086 16.3 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PXF42779.1 - 0.00067 19.1 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.16 PXF42779.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family KH_1 PF00013.29 PXF42779.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 KH domain MeaB PF03308.16 PXF42779.1 - 0.012 14.7 0.0 0.76 8.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 PXF42779.1 - 0.015 14.9 0.0 0.039 13.5 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 PXF42779.1 - 0.017 14.5 0.0 0.088 12.3 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.9 PXF42779.1 - 0.04 13.7 0.0 4.5 7.0 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 PXF42779.1 - 0.053 12.6 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_9 PF12781.7 PXF42779.1 - 0.056 12.6 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 ATP-binding dynein motor region Ras PF00071.22 PXF42779.1 - 0.12 12.0 0.0 0.87 9.2 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_28 PF13521.6 PXF42779.1 - 0.13 12.5 0.1 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain ubiquitin PF00240.23 PXF42780.1 - 3.7e-34 116.3 0.8 4.8e-34 115.9 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 PXF42780.1 - 3.6e-28 97.2 11.0 5.6e-28 96.6 11.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 PXF42780.1 - 2.1e-16 59.5 0.8 2.9e-16 59.1 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PXF42780.1 - 1.1e-05 25.7 0.3 3.9e-05 24.0 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 PXF42780.1 - 0.0055 17.0 0.1 0.0085 16.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 PXF42780.1 - 0.0058 16.6 1.4 0.85 9.7 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PXF42780.1 - 0.0073 16.4 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PXF42780.1 - 0.0079 16.1 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Sde2_N_Ubi PF13019.6 PXF42780.1 - 0.024 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 PXF42780.1 - 0.033 14.8 0.1 0.041 14.4 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Bromodomain PF00439.25 PXF42781.1 - 9.8e-19 67.2 0.1 1.9e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain DNMT1-RFD PF12047.8 PXF42781.1 - 4e-11 43.2 0.3 3.8e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain START PF01852.19 PXF42782.1 - 1.2e-05 24.8 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 START domain HCMV_UL139 PF12507.8 PXF42782.1 - 0.03 14.7 0.1 0.068 13.6 0.1 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein SRP_TPR_like PF17004.5 PXF42782.1 - 0.04 13.9 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat Peptidase_M1 PF01433.20 PXF42783.1 - 4.2e-40 137.6 0.0 7.6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PXF42783.1 - 3.4e-28 98.0 0.1 7e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PXF42783.1 - 4.6e-17 62.8 0.0 8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF596 PF04591.12 PXF42783.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF596 SATase_N PF06426.14 PXF42784.1 - 1.4e-31 109.0 0.4 2e-31 108.4 0.4 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 PXF42784.1 - 1.8e-12 46.5 10.5 8.5e-08 31.6 2.0 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PXF42784.1 - 0.00082 19.1 10.0 0.028 14.2 3.1 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase TFIIA PF03153.13 PXF42785.1 - 2.7e-20 73.8 0.3 4.9e-14 53.2 0.3 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Trp_dioxygenase PF03301.13 PXF42786.1 - 3.9e-93 312.6 1.4 4.8e-93 312.3 1.4 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase SurA_N_2 PF13623.6 PXF42786.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Tim17 PF02466.19 PXF42787.1 - 3.1e-29 101.6 4.3 4.7e-29 101.0 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 PXF42787.1 - 0.0019 18.3 5.4 0.08 13.1 0.1 2.8 2 1 0 3 3 3 2 LydA holin phage, holin superfamily III COMM_domain PF07258.14 PXF42787.1 - 0.13 12.4 0.5 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 COMM domain 60KD_IMP PF02096.20 PXF42787.1 - 0.18 11.7 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Sybindin PF04099.12 PXF42788.1 - 2.5e-34 118.2 0.0 2.8e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PXF42788.1 - 3.3e-06 27.3 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 PXF42789.1 - 9.7e-16 57.9 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42789.1 - 0.00037 19.9 0.0 0.0049 16.2 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PXF42789.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF42789.1 - 0.012 14.5 0.0 0.073 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Methyltransf_11 PF08241.12 PXF42790.1 - 2.4e-19 69.8 0.1 4.6e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF42790.1 - 3.4e-17 62.8 0.0 4.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF42790.1 - 7.6e-15 55.0 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF42790.1 - 1.2e-14 54.8 0.1 2.2e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF42790.1 - 1.5e-12 48.1 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF42790.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 PXF42790.1 - 2.3e-07 30.5 0.5 3.4e-07 29.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 PXF42790.1 - 9.9e-06 24.7 0.0 1.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 PXF42790.1 - 0.00061 19.4 0.2 0.0011 18.5 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 PXF42790.1 - 0.0025 17.5 0.1 0.0038 16.9 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PXF42790.1 - 0.0056 16.7 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 PXF42790.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase ADH_zinc_N PF00107.26 PXF42790.1 - 0.048 13.6 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPMT PF05724.11 PXF42790.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 PXF42790.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Plant_tran PF04827.14 PXF42793.1 - 1.4e-12 47.7 0.3 3.3e-12 46.5 0.1 1.6 2 0 0 2 2 2 1 Plant transposon protein WD40 PF00400.32 PXF42795.1 - 9.8e-19 67.4 13.7 4.6e-06 27.3 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat 2-oxoacid_dh PF00198.23 PXF42796.1 - 2.5e-61 207.1 0.3 3.8e-61 206.5 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PXF42796.1 - 4.6e-33 112.9 11.3 1.6e-17 63.1 2.3 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 PXF42796.1 - 1.5e-25 89.2 3.8 3.1e-12 46.6 0.3 2.6 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.6 PXF42796.1 - 0.0086 15.9 0.8 3.5 7.5 0.1 3.0 2 1 0 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 PXF42796.1 - 0.024 14.5 2.6 5.4 6.9 0.2 2.8 2 0 0 2 2 2 0 Glycine cleavage H-protein PYNP_C PF07831.13 PXF42796.1 - 0.046 13.4 0.2 7 6.4 0.0 2.8 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain BUD22 PF09073.10 PXF42796.1 - 0.083 12.2 2.0 0.11 11.8 0.1 2.0 1 1 1 2 2 2 0 BUD22 TP2 PF01254.18 PXF42796.1 - 0.12 12.9 0.4 0.12 12.9 0.4 1.9 2 0 0 2 2 2 0 Nuclear transition protein 2 HlyD_3 PF13437.6 PXF42796.1 - 0.31 11.8 6.4 11 6.8 0.2 4.0 3 2 2 5 5 5 0 HlyD family secretion protein CCDC53 PF10152.9 PXF42796.1 - 7 7.0 10.4 12 6.3 0.5 3.2 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Glyco_hydro_16 PF00722.21 PXF42797.1 - 1.7e-11 43.9 2.3 3.7e-11 42.8 1.9 1.6 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Imm64 PF15600.6 PXF42797.1 - 0.029 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 64 OAD_beta PF03977.13 PXF42799.1 - 0.18 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit MCR PF18509.1 PXF42800.1 - 0.026 14.1 0.3 0.043 13.4 0.3 1.3 1 0 0 1 1 1 0 Magnetochrome domain Peptidase_M1 PF01433.20 PXF42801.1 - 7.1e-38 130.4 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PXF42801.1 - 6.5e-23 81.0 0.0 1.3e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PXF42801.1 - 6e-16 59.2 0.0 8.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain PAP2 PF01569.21 PXF42802.1 - 1.2e-07 31.5 4.7 1.7e-05 24.6 0.3 2.9 3 0 0 3 3 3 2 PAP2 superfamily VCPO_N PF17897.1 PXF42802.1 - 0.00034 20.5 0.3 0.00069 19.5 0.3 1.5 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain Nodulin_late PF07127.11 PXF42802.1 - 0.0044 17.3 0.2 0.0097 16.2 0.2 1.6 1 0 0 1 1 1 1 Late nodulin protein DX PF01666.17 PXF42802.1 - 0.2 12.1 1.2 5.1 7.6 0.2 2.3 2 0 0 2 2 2 0 DX module Dickkopf_N PF04706.12 PXF42802.1 - 0.31 11.6 3.9 1.9 9.0 0.2 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 PXF42802.1 - 2.3 8.6 4.6 12 6.3 0.1 2.5 3 0 0 3 3 3 0 EB module Glyco_transf_7C PF02709.14 PXF42803.1 - 3.4e-07 29.8 0.0 8.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PXF42803.1 - 5.9e-06 26.0 0.1 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF42803.1 - 9.6e-05 22.3 0.5 0.00028 20.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 NodZ PF05830.11 PXF42803.1 - 0.00054 18.9 0.1 0.047 12.5 0.0 2.4 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PXF42803.1 - 0.017 13.8 0.0 0.12 10.9 0.0 1.9 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Trp_Tyr_perm PF03222.13 PXF42804.1 - 1.3e-48 166.1 22.4 4.7e-20 72.0 0.5 3.0 1 1 2 3 3 3 3 Tryptophan/tyrosine permease family Aa_trans PF01490.18 PXF42804.1 - 0.00062 18.6 16.5 0.0011 17.7 16.5 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1180 PF06679.12 PXF42804.1 - 2.9 8.3 6.3 0.17 12.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Glu_cyclase_2 PF05096.12 PXF42809.1 - 3.4e-71 239.6 0.1 4.1e-71 239.4 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase DUF4908 PF16252.5 PXF42809.1 - 0.0065 16.0 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4908) DEAD_2 PF06733.15 PXF42810.1 - 1e-46 158.7 0.1 2e-46 157.8 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 PXF42810.1 - 3.3e-43 147.8 0.1 7.4e-43 146.7 0.1 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 PXF42810.1 - 3.1e-29 102.0 0.4 6.6e-22 78.1 0.1 2.8 2 1 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 PXF42810.1 - 8.5e-08 32.4 0.0 9.8e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF42810.1 - 0.0055 16.5 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 PXF42810.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PXF42810.1 - 0.072 13.4 0.1 4 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 PXF42811.1 - 1.6e-50 171.3 0.6 5.7e-44 149.9 0.3 2.9 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 PXF42811.1 - 7.5e-24 84.0 0.3 1.3e-23 83.3 0.3 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF42811.1 - 2.4e-15 56.7 4.2 4.6e-15 55.8 4.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PXF42811.1 - 2.7e-05 23.7 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TetR_C_22 PF17928.1 PXF42811.1 - 0.0093 16.3 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Coprogen_oxidas PF01218.18 PXF42812.1 - 2.6e-135 449.9 0.0 3.1e-135 449.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase RNA_pol_L_2 PF13656.6 PXF42813.1 - 3e-21 75.0 0.0 4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PXF42813.1 - 9.6e-06 24.9 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 PXF42813.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Snf7 PF03357.21 PXF42814.1 - 2.7e-11 43.4 16.7 1.2e-10 41.3 16.7 1.9 1 1 0 1 1 1 1 Snf7 AbiEi_4 PF13338.6 PXF42814.1 - 0.0075 16.4 0.1 7.6 6.8 0.0 3.3 3 0 0 3 3 3 2 Transcriptional regulator, AbiEi antitoxin Aminotran_4 PF01063.19 PXF42815.1 - 2e-16 60.5 0.0 3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV CTK3 PF12243.8 PXF42815.1 - 0.0096 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF604 PF04646.12 PXF42815.1 - 0.1 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Arf PF00025.21 PXF42816.1 - 1.7e-45 154.6 0.0 2.1e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PXF42816.1 - 7.7e-10 38.5 0.0 9.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PXF42816.1 - 1e-09 38.0 0.1 5e-08 32.5 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.22 PXF42816.1 - 3.2e-07 30.1 0.0 3.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF42816.1 - 3.4e-07 30.5 0.0 6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PXF42816.1 - 1.5e-05 24.5 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF42816.1 - 0.00076 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C2H2 PF00096.26 PXF42817.1 - 3.9e-11 42.8 18.5 4e-05 23.8 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF42817.1 - 8.5e-06 26.0 15.3 0.032 14.7 1.5 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF42817.1 - 0.00038 21.1 27.1 0.0045 17.7 1.0 4.3 4 0 0 4 4 3 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF42817.1 - 0.015 14.9 0.5 0.039 13.6 0.5 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 PXF42817.1 - 0.017 15.1 0.0 0.017 15.1 0.0 2.8 3 1 1 4 4 4 0 BED zinc finger zf-met PF12874.7 PXF42817.1 - 0.032 14.6 6.8 1.2 9.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 PXF42817.1 - 0.049 14.3 12.5 0.16 12.7 8.3 3.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats RNA_POL_M_15KD PF02150.16 PXF42817.1 - 0.13 12.2 0.7 0.88 9.5 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Actin_micro PF17003.5 PXF42817.1 - 1.3 8.1 8.9 2.3 7.3 2.5 2.7 1 1 1 2 2 2 0 Putative actin-like family OrfB_Zn_ribbon PF07282.11 PXF42817.1 - 1.5 8.8 11.5 0.49 10.4 1.0 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.8 PXF42817.1 - 1.6 9.1 6.8 1.7 9.0 2.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Nudix_N_2 PF14803.6 PXF42817.1 - 2.6 8.1 5.3 1.1 9.3 1.2 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf-C2H2_6 PF13912.6 PXF42817.1 - 7.4 6.7 20.8 0.62 10.1 0.3 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Glycos_transf_2 PF00535.26 PXF42818.1 - 5.9e-27 94.5 0.0 7.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF42818.1 - 1.2e-09 38.4 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PXF42818.1 - 0.0031 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 PXF42818.1 - 0.0052 16.3 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Meiosis_expr PF15163.6 PXF42818.1 - 0.078 13.7 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Meiosis-expressed Aminotran_1_2 PF00155.21 PXF42819.1 - 1.4e-62 212.0 0.0 1.7e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PXF42819.1 - 1e-06 28.3 0.0 6.1e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF42819.1 - 0.00095 17.8 0.0 0.0016 17.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PXF42819.1 - 0.0071 15.3 0.0 0.035 13.1 0.0 2.0 3 0 0 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PXF42819.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L29 PF00831.23 PXF42819.1 - 0.13 12.2 0.1 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein Utp12 PF04003.12 PXF42820.1 - 5.8e-15 55.5 0.1 1.3e-14 54.4 0.1 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 PXF42820.1 - 0.0041 17.9 0.0 0.022 15.6 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Beta_propel PF09826.9 PXF42820.1 - 0.066 12.1 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Beta propeller domain Thioredoxin PF00085.20 PXF42821.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF42821.1 - 0.00089 19.7 0.3 0.0051 17.2 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 PXF42821.1 - 0.0014 18.5 0.1 0.0014 18.5 0.1 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 PXF42821.1 - 0.023 14.1 0.6 0.043 13.2 0.2 1.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 PXF42821.1 - 0.05 13.5 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain RskA PF10099.9 PXF42821.1 - 0.086 13.1 2.1 0.11 12.8 2.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA AAA_assoc_C PF09821.9 PXF42822.1 - 1.9e-31 109.0 0.1 3.1e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain ABC_tran PF00005.27 PXF42822.1 - 6.8e-08 33.1 0.0 2.2e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter DNA_pol_B_exo1 PF03104.19 PXF42826.1 - 0.00017 20.9 0.0 0.0002 20.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain E2 PF08199.11 PXF42826.1 - 0.069 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage E2-like protein Chromate_transp PF02417.15 PXF42827.1 - 0.00089 19.4 0.2 0.00089 19.4 0.2 1.8 2 0 0 2 2 2 1 Chromate transporter RNase_PH PF01138.21 PXF42834.1 - 5.7e-35 120.7 0.1 7.7e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF42834.1 - 8.1e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cornichon PF03311.14 PXF42835.1 - 2.3e-38 131.3 8.2 2.7e-38 131.0 8.2 1.1 1 0 0 1 1 1 1 Cornichon protein Tmemb_14 PF03647.13 PXF42836.1 - 1.8e-18 67.0 15.2 2.1e-18 66.8 13.9 1.6 2 0 0 2 2 2 1 Transmembrane proteins 14C Wzy_C PF04932.15 PXF42836.1 - 5 6.7 7.3 14 5.3 7.3 1.7 1 1 0 1 1 1 0 O-Antigen ligase Coq4 PF05019.13 PXF42837.1 - 5.1e-67 225.4 0.0 5.8e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 V-SNARE_C PF12352.8 PXF42838.1 - 2.9e-14 53.1 4.8 2.9e-14 53.1 4.8 2.7 2 1 1 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PXF42838.1 - 8.5e-06 25.6 6.7 4.2e-05 23.4 0.5 2.4 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 PXF42838.1 - 0.00044 20.6 5.1 0.00072 19.9 2.5 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Glutaredoxin2_C PF04399.13 PXF42838.1 - 0.056 13.3 0.6 0.23 11.3 0.1 2.0 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain PTS_IIA PF02255.16 PXF42838.1 - 0.33 11.0 5.8 0.17 11.9 2.0 2.4 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4407 PF14362.6 PXF42838.1 - 0.36 10.1 11.0 0.97 8.7 11.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fusion_gly PF00523.18 PXF42838.1 - 0.47 8.6 8.7 0.44 8.7 1.7 2.8 2 1 1 3 3 3 0 Fusion glycoprotein F0 Hema_stalk PF08720.10 PXF42838.1 - 0.51 10.0 4.1 0.14 11.9 1.1 1.6 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk DUF883 PF05957.13 PXF42838.1 - 1.1 9.8 6.1 0.44 11.2 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Sec8_exocyst PF04048.14 PXF42838.1 - 2 8.3 7.4 1.2 9.0 2.0 2.7 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain Exonuc_VII_L PF02601.15 PXF42838.1 - 4.8 6.6 10.5 16 5.0 10.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_18 PF00704.28 PXF42839.1 - 2e-13 50.8 0.0 2.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 PXF42839.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 NAPRTase_N PF17767.1 PXF42840.1 - 1.1e-36 126.0 0.0 1.9e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 PXF42840.1 - 8.8e-15 55.1 0.1 1.6e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 PXF42840.1 - 3.9e-11 43.0 0.1 8.2e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 PXF42840.1 - 0.0038 17.2 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain NPV_P10 PF05531.12 PXF42841.1 - 0.017 15.6 2.0 1.2 9.6 2.0 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 PXF42841.1 - 0.025 14.6 2.6 0.16 12.0 2.6 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PXF42841.1 - 0.029 14.4 0.1 1.1 9.3 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 PXF42841.1 - 0.048 14.0 0.0 0.098 13.0 0.0 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region BORCS7 PF16088.5 PXF42841.1 - 0.052 13.8 0.3 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Cep57_MT_bd PF06657.13 PXF42841.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 PXF42841.1 - 0.093 13.4 1.2 2.9 8.6 0.2 2.5 2 1 1 3 3 3 0 SlyX DUF948 PF06103.11 PXF42841.1 - 0.096 13.0 2.7 2.9 8.2 2.7 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.10 PXF42841.1 - 0.55 10.1 2.7 3.5 7.5 0.1 2.8 2 1 1 3 3 3 0 DASH complex subunit Dam1 DDE_Tnp_4 PF13359.6 PXF42843.1 - 5.1e-20 71.7 0.0 6.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA_synt_1c_R1 PF04558.15 PXF42844.1 - 0.021 14.8 3.4 0.05 13.6 0.0 2.5 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 GMC_oxred_N PF00732.19 PXF42845.1 - 8.4e-36 123.8 0.0 1.3e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF42845.1 - 8.2e-21 75.0 0.0 1.5e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PXF42845.1 - 0.0013 18.9 0.4 0.019 15.2 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PXF42845.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PXF42845.1 - 0.034 13.4 0.0 0.52 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF42845.1 - 0.037 13.6 0.1 0.47 10.0 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 PXF42845.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AAA_23 PF13476.6 PXF42849.1 - 0.00032 21.3 14.3 0.011 16.3 7.7 2.5 2 0 0 2 2 2 2 AAA domain DUF1664 PF07889.12 PXF42849.1 - 0.0031 17.5 2.3 0.0031 17.5 2.3 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1664) Spectrin PF00435.21 PXF42849.1 - 0.48 10.9 16.8 0.13 12.8 4.5 3.3 2 1 1 3 3 3 0 Spectrin repeat FYVE_2 PF02318.16 PXF42849.1 - 0.63 10.3 8.0 6.2 7.1 1.3 3.2 2 0 0 2 2 2 0 FYVE-type zinc finger CCDC-167 PF15188.6 PXF42849.1 - 7.6 7.0 13.6 4.9 7.6 2.7 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Helicase_C PF00271.31 PXF42850.1 - 6.1e-11 42.6 0.0 1.7e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF42851.1 - 7.8e-09 35.5 0.0 8.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-B_N PF04218.13 PXF42855.1 - 7.9e-07 28.6 0.8 1.3e-06 27.9 0.8 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 PXF42855.1 - 5.7e-06 26.3 0.1 9.6e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 PXF42855.1 - 1.1e-05 25.5 0.3 3.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 PXF42855.1 - 0.00094 18.9 4.5 0.0015 18.3 0.1 2.7 3 1 0 3 3 3 1 Homeodomain-like domain NmrA PF05368.13 PXF42855.1 - 0.0036 16.9 0.1 0.0055 16.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family HTH_29 PF13551.6 PXF42855.1 - 0.018 15.0 0.3 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 PXF42855.1 - 0.029 14.1 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.19 PXF42855.1 - 0.052 13.1 0.3 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 PXF42855.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase RT_RNaseH PF17917.1 PXF42858.1 - 4.8e-18 65.4 0.1 7.9e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PXF42858.1 - 1.7e-06 28.0 0.1 7e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase C2 PF00168.30 PXF42859.1 - 3.2e-05 24.2 0.1 7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 C2 domain FerI PF08151.12 PXF42859.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 FerI (NUC094) domain Transposase_21 PF02992.14 PXF42861.1 - 4.3e-08 32.7 0.0 7.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 SnAPC_2_like PF11035.8 PXF42865.1 - 0.0011 19.2 2.1 0.0015 18.8 1.6 1.4 1 1 0 1 1 1 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Myb_DNA-binding PF00249.31 PXF42865.1 - 0.011 15.9 0.2 0.053 13.7 0.2 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 PXF42867.1 - 3.5e-05 24.3 24.4 0.024 15.4 0.3 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF42867.1 - 0.00076 19.8 22.7 0.095 13.2 0.4 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 PXF42867.1 - 0.0044 17.6 7.7 0.75 10.5 0.1 3.2 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-BED PF02892.15 PXF42867.1 - 0.015 15.3 1.8 0.015 15.3 1.8 3.5 2 2 2 4 4 4 0 BED zinc finger zf-Di19 PF05605.12 PXF42867.1 - 0.067 13.5 13.0 0.11 12.8 1.7 3.2 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 PXF42867.1 - 0.2 11.7 13.4 4.2 7.5 5.1 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.6 PXF42867.1 - 0.27 11.3 0.3 0.27 11.3 0.3 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 PXF42867.1 - 5.1 7.9 12.0 2e+03 -0.4 12.0 2.3 1 1 0 1 1 1 0 zinc-ribbon family Zn-C2H2_12 PF18112.1 PXF42867.1 - 6 7.4 8.4 0.57 10.7 0.7 2.9 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_C2H2_ZHX PF18387.1 PXF42867.1 - 7.5 6.3 12.8 3.2 7.5 1.7 3.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Pkinase PF00069.25 PXF42869.1 - 7.8e-22 77.9 0.0 9.8e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PXF42869.1 - 7.4e-08 31.6 0.0 1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 PXF42869.1 - 8.1e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF42869.1 - 0.0025 17.8 0.0 0.0061 16.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF42869.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_4 PF01565.23 PXF42871.1 - 1.1e-21 77.1 2.3 1.8e-21 76.3 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PXF42871.1 - 6.2e-12 45.4 0.2 1.4e-11 44.3 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like WRKY PF03106.15 PXF42874.1 - 0.048 13.9 0.3 0.092 13.0 0.3 1.4 1 0 0 1 1 1 0 WRKY DNA -binding domain Ephrin_rec_like PF07699.13 PXF42881.1 - 1.6e-05 24.5 9.7 2.5e-05 23.9 7.3 2.3 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 PXF42881.1 - 0.003 17.5 1.5 0.003 17.5 1.5 1.7 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR cEGF PF12662.7 PXF42881.1 - 0.43 10.6 11.8 0.53 10.3 0.8 2.9 3 0 0 3 3 3 0 Complement Clr-like EGF-like Glyoxalase PF00903.25 PXF42884.1 - 1.1e-06 28.9 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF42884.1 - 0.0024 18.1 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PXF42884.1 - 0.0039 17.3 0.0 1.5 8.9 0.0 2.0 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 PXF42885.1 - 1.1e-06 28.9 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF42885.1 - 0.0024 18.1 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PXF42885.1 - 0.0039 17.3 0.0 1.5 8.9 0.0 2.0 2 0 0 2 2 2 2 Glyoxalase-like domain Pkinase PF00069.25 PXF42891.1 - 2.2e-71 240.3 0.0 4.1e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42891.1 - 7.7e-50 169.6 0.0 1.3e-49 168.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF42891.1 - 1.5e-05 24.0 0.0 3.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF42891.1 - 0.0042 16.5 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF42891.1 - 0.03 14.2 0.1 0.98 9.3 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF42891.1 - 0.036 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 PXF42891.1 - 0.08 12.5 0.2 0.36 10.4 0.2 2.0 1 1 0 1 1 1 0 RIO1 family Med6 PF04934.14 PXF42892.1 - 5.9e-40 136.1 0.1 7.8e-40 135.8 0.1 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component NUDIX PF00293.28 PXF42893.1 - 6e-07 29.6 0.1 9.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain EAP30 PF04157.16 PXF42895.1 - 1e-26 93.7 0.7 1.5e-26 93.1 0.7 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 PXF42895.1 - 0.00016 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HTH_Crp_2 PF13545.6 PXF42895.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain BBL5 PF07289.11 PXF42895.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein zf-C2H2 PF00096.26 PXF42896.1 - 3.1e-17 62.0 27.6 0.00016 21.9 0.3 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF42896.1 - 7e-14 51.5 32.8 0.00016 21.9 0.4 5.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF42896.1 - 2.3e-13 49.8 28.5 0.0028 18.3 0.2 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF42896.1 - 3.8e-05 24.3 12.0 0.48 11.1 0.0 3.9 2 1 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 PXF42896.1 - 0.00072 19.8 4.2 0.00072 19.8 4.2 3.0 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 PXF42896.1 - 0.0032 17.2 0.4 0.0032 17.2 0.4 4.3 4 0 0 4 4 4 1 zinc-finger C2H2-type ADK_lid PF05191.14 PXF42896.1 - 0.0042 17.0 0.5 0.089 12.8 0.0 2.9 2 1 0 2 2 2 1 Adenylate kinase, active site lid Actin_micro PF17003.5 PXF42896.1 - 0.008 15.4 6.9 0.27 10.4 0.3 2.4 1 1 1 2 2 2 2 Putative actin-like family DGF-1_C PF11040.8 PXF42896.1 - 0.018 15.0 0.6 0.034 14.1 0.6 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus zf-C2HE PF16278.5 PXF42896.1 - 0.024 15.1 14.4 0.6 10.6 0.2 4.0 1 1 4 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger SR-25 PF10500.9 PXF42896.1 - 1.2 8.7 11.8 0.12 12.0 7.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 PXF42896.1 - 2.5 6.4 4.4 3.5 6.0 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FOXP-CC PF16159.5 PXF42896.1 - 4.5 8.0 14.5 0.68 10.6 3.4 3.8 3 2 1 4 4 4 0 FOXP coiled-coil domain HalOD2 PF18547.1 PXF42896.1 - 7.1 6.6 7.5 29 4.6 0.1 3.7 4 0 0 4 4 4 0 Halobacterial output domain 2 zf-AN1 PF01428.16 PXF42896.1 - 9.4 6.5 19.9 4.5 7.5 0.1 4.9 4 1 1 5 5 4 0 AN1-like Zinc finger zf-C2H2 PF00096.26 PXF42897.1 - 0.0066 16.9 3.1 0.021 15.3 3.1 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42897.1 - 0.031 15.1 2.3 0.072 14.0 2.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Metallophos PF00149.28 PXF42898.1 - 0.061 13.8 0.0 0.061 13.8 0.0 1.0 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase F-box-like PF12937.7 PXF42899.1 - 9.7e-06 25.4 0.1 5.6e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 PXF42899.1 - 0.017 15.0 0.8 0.7 9.8 0.1 2.7 3 0 0 3 3 3 0 F-box MFS_1 PF07690.16 PXF42901.1 - 1.8e-16 60.0 31.8 1.8e-16 60.0 31.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 PXF42901.1 - 1.3e-09 37.1 25.6 6.8e-08 31.5 5.6 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein Actin PF00022.19 PXF42904.1 - 2e-67 227.6 0.0 1.5e-66 224.7 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PXF42904.1 - 0.0001 21.3 0.0 0.0016 17.3 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein DAHP_synth_2 PF01474.16 PXF42905.1 - 6.2e-187 621.4 0.0 7.1e-187 621.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family AhpC-TSA PF00578.21 PXF42906.1 - 4.4e-32 110.6 0.0 5.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF42906.1 - 4.8e-13 49.1 0.0 8.4e-13 48.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PXF42906.1 - 1.5e-10 40.7 0.1 2.6e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Gmad1 PF10647.9 PXF42906.1 - 0.051 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Pkinase PF00069.25 PXF42907.1 - 1.5e-69 234.3 0.0 1.9e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42907.1 - 2.7e-37 128.5 0.0 3.9e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF42907.1 - 1.4e-05 24.1 0.0 2.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF42907.1 - 0.00065 19.1 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 PXF42907.1 - 0.088 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 PH domain AhpC-TSA PF00578.21 PXF42908.1 - 1.8e-15 57.0 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF42908.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin Pkinase PF00069.25 PXF42909.1 - 2.7e-74 249.9 0.0 3.6e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42909.1 - 6.7e-36 123.9 0.0 1.2e-35 123.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42909.1 - 3.8e-05 23.1 0.0 0.00011 21.6 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF42909.1 - 0.00056 19.3 0.1 0.00097 18.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF42909.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PXF42909.1 - 0.019 14.5 0.2 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Adenylsucc_synt PF00709.21 PXF42910.1 - 4.3e-171 569.5 0.0 4.9e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Rabaptin PF03528.15 PXF42913.1 - 0.0085 14.8 0.3 0.0093 14.7 0.3 1.0 1 0 0 1 1 1 1 Rabaptin Pns11_12 PF17464.2 PXF42913.1 - 0.035 13.8 0.8 0.04 13.6 0.8 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 HTH_19 PF12844.7 PXF42913.1 - 0.044 13.8 0.1 0.11 12.5 0.0 1.7 2 1 0 2 2 2 0 Helix-turn-helix domain SLC3A2_N PF16028.5 PXF42914.1 - 0.14 11.7 0.6 12 5.5 0.1 2.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus tRNA_synthFbeta PF17759.1 PXF42914.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain SelP_C PF04593.14 PXF42916.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 Selenoprotein P, C terminal region zf-CSL PF05207.13 PXF42919.1 - 8.6e-19 67.0 0.2 1.1e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 PXF42919.1 - 0.0086 16.2 0.3 0.0086 16.2 0.3 2.1 2 0 0 2 2 2 1 Zinc ribbon domain zf-RING_7 PF02591.15 PXF42919.1 - 0.011 16.0 0.1 0.011 16.0 0.1 1.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 PXF42919.1 - 0.042 13.8 0.4 0.042 13.8 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 PXF42919.1 - 0.88 9.5 4.3 13 5.8 4.4 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Myb_DNA-binding PF00249.31 PXF42920.1 - 2.6e-31 107.6 1.3 1.4e-16 60.4 0.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF42920.1 - 3.4e-26 91.3 1.1 1.5e-18 66.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 PXF42920.1 - 7.5e-05 22.7 0.1 0.024 14.6 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 PXF42920.1 - 0.0032 17.3 0.5 3.5 7.6 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 PXF42920.1 - 0.008 16.3 0.8 1.8 8.8 0.1 2.9 1 1 1 2 2 2 2 Rap1 Myb domain Pkinase PF00069.25 PXF42921.1 - 3.2e-58 197.2 0.0 4.6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42921.1 - 1.1e-38 133.0 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 PXF42921.1 - 3.4e-13 49.7 0.0 8.7e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 PXF42921.1 - 2.7e-05 23.1 0.0 4.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF42921.1 - 0.04 13.8 0.1 0.4 10.6 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC1 PF03109.16 PXF42921.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 PXF42921.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Thioredoxin PF00085.20 PXF42922.1 - 2e-15 56.7 0.0 2.5e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 PXF42922.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 PXF42922.1 - 0.034 14.6 0.0 0.32 11.5 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PXF42922.1 - 0.087 13.2 0.0 4.3 7.7 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like PAH PF02671.21 PXF42923.1 - 1.3e-37 127.6 7.3 1.1e-15 57.5 0.1 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 PXF42923.1 - 6.9e-07 29.3 0.0 0.0098 15.9 0.0 2.8 2 0 0 2 2 2 2 Sin3 family co-repressor DEAD PF00270.29 PXF42925.1 - 3.8e-31 108.2 0.1 5.6e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF42925.1 - 1.2e-25 90.0 0.1 3e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF42925.1 - 1.1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF42925.1 - 2.5e-05 24.6 0.0 0.00052 20.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PXF42925.1 - 0.0084 16.4 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain HEM4 PF02602.15 PXF42925.1 - 0.06 12.7 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AAA PF00004.29 PXF42925.1 - 0.092 13.2 0.1 0.54 10.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 PXF42926.1 - 8e-12 44.7 28.0 8e-12 44.7 28.0 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily PIG-Y PF15159.6 PXF42926.1 - 0.26 12.2 3.4 0.96 10.4 1.0 3.2 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y YtxH PF12732.7 PXF42927.1 - 0.029 14.9 0.5 2 9.0 0.1 3.1 2 1 0 2 2 2 0 YtxH-like protein FPP PF05911.11 PXF42927.1 - 0.032 12.4 5.9 1.3 7.1 0.1 2.7 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil Sec34 PF04136.15 PXF42927.1 - 0.066 13.1 4.1 0.4 10.6 0.5 3.1 3 0 0 3 3 3 0 Sec34-like family Phasin_2 PF09361.10 PXF42927.1 - 0.069 13.4 0.4 24 5.3 0.0 3.4 4 0 0 4 4 4 0 Phasin protein DUF3450 PF11932.8 PXF42927.1 - 0.076 12.3 0.7 1.4 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CK2S PF15011.6 PXF42927.1 - 0.078 12.9 6.6 3.5 7.5 0.1 3.4 3 0 0 3 3 3 0 Casein Kinase 2 substrate V_ATPase_I PF01496.19 PXF42927.1 - 0.16 9.9 2.2 0.14 10.0 0.2 1.8 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PqqD PF05402.12 PXF42927.1 - 0.18 12.1 0.5 1.5 9.2 0.1 2.8 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Laminin_II PF06009.12 PXF42927.1 - 0.26 11.3 2.3 9 6.3 0.1 3.1 3 0 0 3 3 3 0 Laminin Domain II betaPIX_CC PF16523.5 PXF42927.1 - 0.37 10.7 5.2 0.13 12.1 1.9 1.9 2 0 0 2 2 2 0 betaPIX coiled coil Fib_alpha PF08702.10 PXF42927.1 - 0.38 10.9 3.0 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 PXF42927.1 - 0.54 11.0 1.9 4 8.2 0.0 3.1 3 1 1 4 4 3 0 Uncharacterized conserved protein (DUF2203) APG17 PF04108.12 PXF42927.1 - 0.65 9.0 5.1 6.5 5.8 0.5 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 BLOC1_2 PF10046.9 PXF42927.1 - 4.3 7.7 6.8 2.6 8.4 0.1 3.7 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 PXF42927.1 - 4.3 7.3 8.7 2.1 8.3 0.4 3.4 3 0 0 3 3 3 0 Prefoldin subunit Rieske PF00355.26 PXF42928.1 - 3e-11 43.1 0.1 5.6e-11 42.2 0.1 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 PXF42928.1 - 1.7e-09 38.1 0.1 3.1e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region ETF_alpha PF00766.19 PXF42929.1 - 6e-36 122.3 0.7 1.3e-35 121.2 0.3 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 PXF42929.1 - 1.7e-28 99.7 3.1 2.8e-28 99.0 3.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Fe-ADH PF00465.19 PXF42930.1 - 5.6e-20 71.5 0.0 5.1e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 PXF42930.1 - 0.00024 20.9 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 PXF42930.1 - 0.07 12.3 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase Mito_carr PF00153.27 PXF42931.1 - 1.4e-13 50.6 6.6 0.0008 19.3 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pro_isomerase PF00160.21 PXF42935.1 - 9.4e-46 156.0 0.1 1.1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 PXF42936.1 - 1.6e-13 50.2 22.7 0.00025 21.3 4.9 3.7 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF42936.1 - 1.3e-09 38.1 21.9 0.0031 18.2 0.4 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF42936.1 - 1.4e-07 31.6 19.2 0.00017 21.8 0.8 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PXF42936.1 - 0.0053 17.0 0.4 0.0053 17.0 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Sprouty PF05210.13 PXF42936.1 - 0.0061 16.9 2.2 0.01 16.2 2.2 1.4 1 0 0 1 1 1 1 Sprouty protein (Spry) DZR PF12773.7 PXF42936.1 - 0.0073 16.3 6.0 0.44 10.6 6.0 2.2 1 1 0 1 1 1 1 Double zinc ribbon DUF2256 PF10013.9 PXF42936.1 - 0.011 15.8 4.6 0.85 9.8 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_2 PF12756.7 PXF42936.1 - 0.012 15.9 13.9 0.17 12.3 0.2 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 PXF42936.1 - 0.013 15.6 6.6 6.9 6.9 0.1 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger zf-BED PF02892.15 PXF42936.1 - 0.014 15.4 14.9 0.022 14.8 0.7 3.4 3 0 0 3 3 3 0 BED zinc finger zf-met PF12874.7 PXF42936.1 - 0.015 15.7 15.1 0.54 10.7 2.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 PXF42936.1 - 0.015 15.7 11.0 1 9.9 0.2 3.3 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 PXF42936.1 - 0.021 15.1 8.5 0.16 12.3 1.6 2.5 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 PXF42936.1 - 0.035 13.9 13.0 0.27 11.0 0.2 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 PXF42936.1 - 0.055 13.4 0.4 0.055 13.4 0.4 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 PXF42936.1 - 0.061 13.2 7.9 1.5 8.8 0.7 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain PyrI_C PF02748.15 PXF42936.1 - 0.091 12.7 3.2 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 PXF42936.1 - 0.11 13.2 8.4 2.1 9.0 0.2 2.8 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats MqsA_antitoxin PF15731.5 PXF42936.1 - 0.12 12.5 1.7 1.9 8.6 0.1 2.4 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Zn_Tnp_IS1595 PF12760.7 PXF42936.1 - 0.15 12.0 7.4 0.13 12.3 2.7 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DpnI PF06044.12 PXF42936.1 - 0.19 11.3 6.7 0.18 11.4 1.4 2.2 1 1 1 2 2 2 0 Dam-replacing family Zn-ribbon_8 PF09723.10 PXF42936.1 - 0.24 11.5 7.1 11 6.2 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain XPA_N PF01286.18 PXF42936.1 - 0.28 11.3 5.9 16 5.6 0.1 3.3 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_6 PF13912.6 PXF42936.1 - 0.34 11.0 0.2 0.34 11.0 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 PXF42936.1 - 0.38 10.9 13.5 13 6.0 13.5 2.4 1 1 0 1 1 1 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 PXF42936.1 - 1.1 9.3 7.4 5.4 7.1 1.7 2.5 1 1 1 2 2 2 0 zinc-ribbons zf_UBZ PF18439.1 PXF42936.1 - 1.1 8.9 6.3 16 5.2 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-trcl PF13451.6 PXF42936.1 - 1.7 8.6 9.6 40 4.2 0.4 3.7 3 1 0 3 3 3 0 Probable zinc-ribbon domain zf-HYPF PF07503.12 PXF42936.1 - 3.3 7.6 9.3 13 5.6 3.3 3.0 2 1 0 2 2 2 0 HypF finger FYDLN_acid PF09538.10 PXF42936.1 - 3.5 8.4 0.0 3.5 8.4 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2197 PF09963.9 PXF42936.1 - 6 7.2 8.6 10 6.5 0.9 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) SRP72 PF08492.12 PXF42937.1 - 6.6e-13 48.9 8.2 6.6e-13 48.9 8.2 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 PXF42937.1 - 1.3e-10 41.3 4.1 4.3e-07 30.0 0.3 3.7 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_2 PF07719.17 PXF42937.1 - 0.00097 19.1 20.3 0.1 12.8 1.9 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42937.1 - 0.001 19.1 9.7 35 5.0 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF42937.1 - 0.0057 17.3 33.5 0.006 17.2 0.1 6.8 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PXF42937.1 - 0.015 15.2 11.9 0.81 9.7 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 PXF42937.1 - 0.021 15.0 0.2 0.021 15.0 0.2 4.0 5 1 1 6 6 6 0 Tetratrico peptide repeat TPR_12 PF13424.6 PXF42937.1 - 0.022 15.0 17.5 0.81 10.0 0.7 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 PXF42937.1 - 0.039 14.2 0.2 38 4.8 0.0 4.2 5 0 0 5 5 4 0 PPR repeat Carot_N PF09150.10 PXF42937.1 - 0.052 13.4 0.5 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Orange carotenoid protein, N-terminal ANAPC3 PF12895.7 PXF42937.1 - 0.35 11.1 8.4 12 6.2 0.1 4.8 2 2 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF42937.1 - 0.63 10.2 6.9 5 7.4 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF42937.1 - 0.71 10.9 37.6 1.5 9.9 0.1 9.2 8 2 4 12 12 9 0 Tetratricopeptide repeat HEAT_2 PF13646.6 PXF42937.1 - 1.9 8.9 8.6 3.1 8.3 1.0 4.2 3 1 0 3 3 3 0 HEAT repeats DUF4535 PF15054.6 PXF42938.1 - 8.9e-16 57.4 0.1 9.8e-16 57.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) AA_kinase PF00696.28 PXF42939.1 - 1.5e-36 126.2 0.4 2.1e-36 125.7 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 PXF42939.1 - 1.4e-13 50.6 0.0 2.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 PUA domain PBS_linker_poly PF00427.21 PXF42940.1 - 1.7e-35 121.8 0.2 3.3e-35 120.9 0.2 1.5 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide ABC_tran_CTD PF16326.5 PXF42940.1 - 4.4 7.6 6.4 1 9.7 0.4 2.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain Cu-oxidase_2 PF07731.14 PXF42943.1 - 9.8e-09 35.1 1.4 1.2e-07 31.5 1.4 2.0 1 1 0 1 1 1 1 Multicopper oxidase APOBEC_C PF05240.14 PXF42944.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 APOBEC-like C-terminal domain WD40 PF00400.32 PXF42947.1 - 2.8e-22 78.6 12.4 0.00053 20.7 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF42947.1 - 6.6e-13 48.8 2.7 3.6e-06 27.2 0.2 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF42947.1 - 9.5e-05 22.4 0.1 0.88 9.4 0.1 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A XRN_N PF03159.18 PXF42948.1 - 4e-91 304.7 0.0 6.7e-91 304.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PXF42948.1 - 6e-86 289.1 3.4 1.5e-61 208.7 0.8 2.3 2 0 0 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 PXF42948.1 - 1.8e-18 66.4 1.6 1.8e-18 66.4 1.6 2.0 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 PXF42948.1 - 1.2e-05 25.1 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain LSM PF01423.22 PXF42949.1 - 8.1e-16 57.5 0.3 1.1e-15 57.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain Nop PF01798.18 PXF42950.1 - 4.9e-84 281.4 0.1 4.9e-84 281.4 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PXF42950.1 - 2.2e-15 56.8 0.2 2.2e-15 56.8 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 PXF42950.1 - 0.12 12.7 33.0 0.3 11.5 33.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 PXF42950.1 - 3.2 7.5 24.1 6 6.6 24.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAP_fibrillin PF04755.12 PXF42951.1 - 3.5e-10 40.2 0.1 2.5e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin MFS_1 PF07690.16 PXF42952.1 - 1.8e-12 46.9 31.2 4.1e-06 25.9 6.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 PXF42952.1 - 2e-08 33.2 7.0 2e-08 33.2 7.0 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 PXF42952.1 - 9.2e-07 28.2 0.1 9.2e-07 28.2 0.1 1.8 2 0 0 2 2 2 1 PUCC protein Methyltransf_11 PF08241.12 PXF42954.1 - 6.8e-10 39.5 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF42954.1 - 2.2e-06 28.3 0.0 7.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF42954.1 - 8.9e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF42954.1 - 0.0028 18.3 0.0 0.0077 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF42954.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 PXF42954.1 - 0.0055 15.3 0.0 0.0078 14.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 PXF42954.1 - 0.0094 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 PXF42954.1 - 0.045 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family YCII PF03795.14 PXF42955.1 - 2.6e-20 72.6 0.0 1.9e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 YCII-related domain NolV PF06635.12 PXF42955.1 - 0.017 14.5 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Nodulation protein NolV MGDG_synth PF06925.11 PXF42956.1 - 1.2e-27 97.0 0.0 1.7e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 PXF42956.1 - 1.7e-13 50.9 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 PXF42956.1 - 1.6e-06 28.6 0.0 5.8e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PXF42956.1 - 0.019 15.4 6.5 0.027 14.9 4.3 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 PXF42956.1 - 0.043 13.8 1.3 0.24 11.4 1.3 2.2 1 1 0 1 1 1 0 Glycosyltransferase Family 4 PI31_Prot_N PF11566.8 PXF42957.1 - 3.6e-16 59.4 0.0 9.6e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 PXF42957.1 - 7.8e-05 23.8 14.1 0.00049 21.2 14.1 2.4 1 1 0 1 1 1 1 PI31 proteasome regulator SKG6 PF08693.10 PXF42957.1 - 0.45 10.0 7.7 0.98 8.9 7.3 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.25 PXF42958.1 - 2.7e-36 125.3 0.0 3.8e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF42958.1 - 3e-17 62.8 0.0 5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF42958.1 - 3.2e-07 30.0 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Mcp5_PH PF12814.7 PXF42958.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology BMFP PF04380.13 PXF42959.1 - 0.099 13.1 0.1 0.59 10.7 0.0 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity Phage_holin_3_6 PF07332.11 PXF42960.1 - 0.00063 19.8 4.0 0.0012 18.9 4.0 1.4 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SseC PF04888.12 PXF42960.1 - 0.0015 18.2 6.2 0.0021 17.7 6.2 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family FemAB_like PF04339.12 PXF42960.1 - 0.01 15.0 2.5 0.015 14.5 2.5 1.3 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition ABC_membrane PF00664.23 PXF42960.1 - 0.016 14.8 0.3 0.024 14.3 0.3 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Med22 PF06179.12 PXF42960.1 - 0.064 13.5 0.3 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex SieB PF14163.6 PXF42961.1 - 0.08 12.4 0.4 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3995 PF13160.6 PXF42961.1 - 0.083 13.3 2.4 0.28 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Peptidase_M15 PF01427.17 PXF42961.1 - 0.11 12.3 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase Lactonase PF10282.9 PXF42963.1 - 1.3e-14 54.2 0.2 0.00015 21.1 0.0 3.8 2 1 2 4 4 4 4 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 PXF42963.1 - 0.14 12.7 2.2 0.42 11.2 0.3 2.8 3 0 0 3 3 3 0 PQQ-like domain DUF3676 PF12429.8 PXF42964.1 - 0.0045 16.9 0.9 0.0051 16.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3676) Integrin_beta PF00362.18 PXF42965.1 - 1.8e-08 34.4 0.0 0.00092 18.9 0.0 2.2 1 1 1 2 2 2 2 Integrin beta chain VWA domain VWA_2 PF13519.6 PXF42965.1 - 0.02 15.5 0.0 0.099 13.3 0.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain DDE_1 PF03184.19 PXF42966.1 - 3.7e-07 30.0 0.0 9.1e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease PI-PLC-X PF00388.19 PXF42967.1 - 1.7e-08 34.2 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF1424 PF07232.11 PXF42968.1 - 0.025 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) gag_pre-integrs PF13976.6 PXF42972.1 - 0.028 14.3 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain Cu-oxidase_2 PF07731.14 PXF42974.1 - 7.7e-08 32.2 0.2 1.3e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Multicopper oxidase Stevor PF17410.2 PXF42976.1 - 0.16 11.5 2.9 0.22 11.1 2.9 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4749 PF15936.5 PXF42977.1 - 0.11 13.6 0.0 0.15 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4749) CHAT PF12770.7 PXF42979.1 - 8.3e-50 169.8 0.0 1.9e-49 168.6 0.0 1.7 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.17 PXF42979.1 - 0.00016 21.5 0.1 0.068 13.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 PXF42979.1 - 0.00019 21.5 1.1 0.27 11.6 0.1 4.3 4 0 0 4 4 4 1 PPR repeat TPR_1 PF00515.28 PXF42979.1 - 0.00024 20.8 1.8 0.012 15.4 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF42979.1 - 0.00042 20.6 3.1 0.72 10.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF42979.1 - 0.0017 18.4 0.0 0.022 14.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF42979.1 - 0.015 15.5 0.2 1.9 8.8 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PXF42979.1 - 0.037 14.7 0.0 4.9 7.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF42979.1 - 0.046 13.8 0.0 0.26 11.4 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR_2 PF13041.6 PXF42979.1 - 0.064 13.5 0.1 3 8.1 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family TPR_10 PF13374.6 PXF42979.1 - 0.12 12.3 0.0 0.6 10.1 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF42979.1 - 0.15 12.7 0.0 31 5.5 0.0 4.2 4 0 0 4 4 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 PXF42979.1 - 0.48 10.2 2.2 5.9 6.7 0.0 3.3 4 0 0 4 4 4 0 PPR repeat Exo_endo_phos PF03372.23 PXF42980.1 - 9.6e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 PXF42980.1 - 2.1e-14 53.3 5.6 4.9e-14 52.1 5.6 1.7 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 PXF42980.1 - 0.00015 21.5 0.4 0.37 10.6 0.3 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase z-alpha PF02295.17 PXF42981.1 - 0.1 12.7 0.7 0.24 11.5 0.7 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain YebO PF13974.6 PXF42981.1 - 4.7 7.4 9.9 0.059 13.4 0.8 2.5 3 0 0 3 3 3 0 YebO-like protein SNF2_N PF00176.23 PXF42984.1 - 5.2e-27 94.5 0.1 1e-26 93.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF42984.1 - 1.2e-11 44.9 0.0 3.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PXF42984.1 - 0.0021 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribonuclease_P PF00825.18 PXF42986.1 - 1.1e-08 35.1 0.2 3.6e-08 33.4 0.2 1.8 1 1 0 1 1 1 1 Ribonuclease P Peptidase_M24 PF00557.24 PXF42987.1 - 6e-49 166.6 0.0 8.1e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PXF42987.1 - 5.1e-28 97.3 0.0 8.7e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SulA PF03846.14 PXF42987.1 - 0.09 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA zf-rbx1 PF12678.7 PXF42988.1 - 3.8e-25 87.9 12.3 5.2e-25 87.5 12.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF42988.1 - 2.5e-18 65.9 8.5 3.1e-18 65.6 8.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 PXF42988.1 - 6.1e-06 26.5 14.8 0.00017 21.8 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF42988.1 - 4.2e-05 23.3 2.2 4.2e-05 23.3 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF42988.1 - 0.00082 19.2 10.9 0.0077 16.1 10.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF42988.1 - 0.51 10.0 14.7 0.11 12.1 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PXF42988.1 - 0.53 10.4 7.1 1.8 8.6 7.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF42988.1 - 0.71 9.8 10.9 2.4 8.1 4.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PXF42988.1 - 0.82 9.9 8.8 3.6 7.8 9.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 PXF42988.1 - 1.1 9.1 17.5 9.6 6.1 17.5 2.2 1 1 0 1 1 1 0 RING-like zinc finger DUF2353 PF09789.9 PXF42989.1 - 0.0065 15.9 3.9 0.0065 15.9 3.9 2.0 2 1 0 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) Mito_carr PF00153.27 PXF42990.1 - 8.6e-17 60.8 2.1 3.4e-05 23.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.19 PXF42991.1 - 4e-34 117.8 0.0 6.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PP2C PF00481.21 PXF42992.1 - 1.2e-47 162.8 0.2 2.8e-46 158.2 0.2 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF42992.1 - 0.00055 19.6 0.1 0.0024 17.5 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PQQ_2 PF13360.6 PXF42993.1 - 0.00031 20.4 0.7 0.0086 15.7 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain SBBP PF06739.11 PXF42993.1 - 0.00039 20.4 3.1 0.00039 20.4 3.1 6.0 6 1 0 6 6 6 3 Beta-propeller repeat Band_7 PF01145.25 PXF42994.1 - 3.7e-11 43.4 0.0 3.7e-11 43.4 0.0 3.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family HTH_11 PF08279.12 PXF42994.1 - 0.029 14.3 0.2 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 HTH domain TMF_DNA_bd PF12329.8 PXF42994.1 - 0.25 11.3 9.2 0.39 10.8 0.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.13 PXF42994.1 - 9.2 6.4 33.1 2.6 8.1 13.7 3.0 1 1 1 2 2 2 0 DivIVA protein WXG100 PF06013.12 PXF42995.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF42995.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF42995.1 - 0.41 11.4 5.2 0.8 10.4 5.2 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain RCC1 PF00415.18 PXF42997.1 - 2.3e-06 28.1 0.1 3.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF42997.1 - 0.097 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Glyco_trans_1_4 PF13692.6 PXF42998.1 - 5.1e-22 78.7 0.2 9.9e-22 77.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PXF42998.1 - 6.5e-22 77.9 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 PXF42998.1 - 7.8e-08 32.3 0.2 1.8e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_1_2 PF13524.6 PXF42998.1 - 0.00043 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Vps5 PF09325.10 PXF43002.1 - 0.0037 16.9 1.5 0.0053 16.3 1.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like DUF883 PF05957.13 PXF43002.1 - 0.42 11.2 5.0 0.61 10.7 1.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) WXG100 PF06013.12 PXF43003.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF43003.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF43003.1 - 0.41 11.4 5.2 0.8 10.4 5.2 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain PAP2 PF01569.21 PXF43004.1 - 0.0082 15.9 0.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 PXF43005.1 - 0.0082 15.9 0.2 0.15 11.8 0.2 2.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 PXF43007.1 - 0.008 15.9 0.1 0.15 11.8 0.2 2.3 1 1 0 1 1 1 1 PAP2 superfamily DUF563 PF04577.14 PXF43008.1 - 8e-20 71.9 1.3 2.4e-19 70.3 1.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Dickkopf_N PF04706.12 PXF43009.1 - 6.7e-13 48.9 37.3 0.00055 20.4 1.5 6.2 3 2 3 6 6 6 6 Dickkopf N-terminal cysteine-rich region EB PF01683.18 PXF43009.1 - 0.02 15.2 4.2 0.02 15.2 4.2 6.5 2 2 4 6 6 6 0 EB module Atg14 PF10186.9 PXF43011.1 - 0.0018 17.4 1.9 0.0021 17.2 1.9 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 PXF43011.1 - 0.068 13.3 2.9 2.3 8.3 0.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 PXF43011.1 - 0.11 12.2 4.8 0.18 11.5 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Pkinase PF00069.25 PXF43013.1 - 2.1e-72 243.7 0.0 2.9e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43013.1 - 1.2e-34 119.8 0.0 2.1e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43013.1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF43013.1 - 0.0021 17.0 0.1 0.0036 16.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF43013.1 - 0.02 14.3 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF43013.1 - 0.048 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Acyl_transf_3 PF01757.22 PXF43014.1 - 1.1e-09 37.8 21.2 1.6e-05 24.2 13.5 2.1 2 0 0 2 2 2 2 Acyltransferase family OppC_N PF12911.7 PXF43015.1 - 0.085 12.8 1.2 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4781 PF16013.5 PXF43015.1 - 0.51 9.1 2.7 0.92 8.3 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) TAL_FSA PF00923.19 PXF43016.1 - 6e-88 294.9 0.0 7e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF759 PF05537.11 PXF43016.1 - 0.22 10.4 0.1 1.1 8.1 0.0 1.9 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) MAP17 PF15807.5 PXF43017.1 - 0.007 16.6 1.8 0.013 15.7 0.1 2.0 2 1 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAP PF07174.11 PXF43017.1 - 0.017 14.6 4.1 0.021 14.3 4.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RXLR PF16810.5 PXF43017.1 - 0.047 14.1 0.2 0.071 13.6 0.2 1.5 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF1180 PF06679.12 PXF43017.1 - 0.061 13.7 6.1 0.12 12.8 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 PXF43017.1 - 1.5 8.3 4.1 2.9 7.4 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LOR PF04525.12 PXF43019.1 - 8.7e-09 35.2 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related Ribosomal_S14 PF00253.21 PXF43020.1 - 7.6e-21 73.6 0.4 1.4e-20 72.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e A2M PF00207.22 PXF43020.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family O-FucT PF10250.9 PXF43023.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.13 PXF43023.1 - 0.09 11.4 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Shisa PF13908.6 PXF43023.1 - 0.32 11.2 1.9 0.68 10.2 1.9 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SPX PF03105.19 PXF43023.1 - 4 7.3 6.5 6.3 6.6 6.5 1.2 1 0 0 1 1 1 0 SPX domain ORC6 PF05460.13 PXF43023.1 - 7.5 5.7 7.7 11 5.2 7.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DDE_1 PF03184.19 PXF43024.1 - 3.3e-10 39.9 0.0 7.8e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Peptidase_U4 PF03419.13 PXF43025.1 - 0.58 9.4 5.8 0.87 8.8 5.8 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA UCH PF00443.29 PXF43026.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Nucleoside_tran PF01733.18 PXF43027.1 - 7.8e-17 61.6 17.9 2.4e-11 43.6 6.8 2.4 2 1 1 3 3 3 2 Nucleoside transporter DUF5079 PF16882.5 PXF43027.1 - 0.06 13.2 0.5 0.16 11.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) Pyr_redox_2 PF07992.14 PXF43028.1 - 1.7e-24 86.6 0.0 2.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF43028.1 - 1.5e-07 31.8 0.0 0.0068 16.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PXF43028.1 - 0.00065 20.1 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PXF43028.1 - 0.0012 18.1 2.3 0.58 9.3 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 PXF43028.1 - 0.0022 18.0 0.2 0.32 11.0 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 PXF43028.1 - 0.012 14.4 0.1 11 4.7 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.18 PXF43028.1 - 0.015 15.6 0.3 4.4 7.6 0.0 2.6 3 0 0 3 3 2 0 TrkA-N domain K_oxygenase PF13434.6 PXF43028.1 - 0.017 14.3 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 PXF43028.1 - 0.085 12.4 0.8 2.6 7.6 0.0 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF43028.1 - 0.1 12.8 0.3 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PXF43028.1 - 0.21 10.6 0.4 37 3.2 0.1 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PXF43028.1 - 0.27 10.4 0.6 1.5 8.0 0.1 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAP_fibrillin PF04755.12 PXF43029.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin Rad51 PF08423.11 PXF43030.1 - 1.1e-112 375.5 0.1 1.3e-112 375.2 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 PXF43030.1 - 1.4e-13 51.0 0.2 2e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PXF43030.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PXF43030.1 - 1e-05 25.0 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.6 PXF43030.1 - 0.0085 16.7 0.8 0.018 15.6 0.3 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.6 PXF43030.1 - 0.033 14.5 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Chordopox_G2 PF05796.12 PXF43030.1 - 0.14 11.6 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 Chordopoxvirus protein G2 Peptidase_S26 PF10502.9 PXF43031.1 - 3.3e-14 52.9 0.0 1.4e-13 50.8 0.0 2.1 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 PXF43031.1 - 8.8e-11 41.6 0.0 2.3e-09 37.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase S24-like Malic_M PF03949.15 PXF43032.1 - 7.9e-90 300.6 0.0 1e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PXF43032.1 - 3.1e-66 222.7 0.0 5e-66 222.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NDUF_B12 PF08122.12 PXF43032.1 - 0.094 12.8 0.9 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Tugs PF17840.1 PXF43034.1 - 0.21 11.8 1.3 0.59 10.4 0.1 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain EF-hand_1 PF00036.32 PXF43035.1 - 1.3e-16 58.8 0.1 6e-07 28.6 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PXF43035.1 - 5.3e-14 50.9 0.5 0.00092 19.0 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PXF43035.1 - 7.8e-13 48.7 0.1 9.2e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PXF43035.1 - 1.2e-08 34.7 1.1 1e-06 28.5 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair Glyoxalase PF00903.25 PXF43035.1 - 1.3e-08 35.0 0.0 5.8e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_5 PF13202.6 PXF43035.1 - 3.8e-06 26.2 0.6 0.15 11.6 0.0 3.3 3 0 0 3 3 3 2 EF hand Glyoxalase_4 PF13669.6 PXF43035.1 - 0.0063 16.8 0.0 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_11 PF08279.12 PXF43035.1 - 0.022 14.7 0.2 0.095 12.7 0.0 2.1 2 0 0 2 2 2 0 HTH domain Dockerin_1 PF00404.18 PXF43035.1 - 0.043 14.0 0.0 9.6 6.5 0.0 2.7 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 PXF43035.1 - 0.077 13.3 0.1 0.84 10.0 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain SNARE_assoc PF09335.11 PXF43036.1 - 0.059 13.9 0.2 0.073 13.6 0.2 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF4648 PF15505.6 PXF43037.1 - 0.12 13.3 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Peptidase_C48 PF02902.19 PXF43038.1 - 1.6e-05 24.9 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Helicase_C PF00271.31 PXF43039.1 - 7.4e-09 35.9 0.0 2.3e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF43039.1 - 3.4e-08 33.5 0.0 7.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase KH_5 PF13184.6 PXF43039.1 - 0.066 13.3 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 NusA-like KH domain OrsD PF12013.8 PXF43039.1 - 3 8.3 12.6 5.9 7.4 5.6 3.4 3 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D SH3BGR PF04908.15 PXF43040.1 - 0.31 11.2 1.4 0.91 9.7 0.0 2.4 3 0 0 3 3 3 0 SH3-binding, glutamic acid-rich protein Helicase_C PF00271.31 PXF43041.1 - 2.3e-09 37.6 0.0 4.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF43042.1 - 1.1e-11 44.8 0.1 3.9e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF43042.1 - 0.00091 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OrsD PF12013.8 PXF43042.1 - 1.7 9.1 13.0 10 6.6 7.9 2.9 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 PXF43042.1 - 4.3 8.4 10.5 59 4.9 5.6 3.5 2 0 0 2 2 2 0 C2H2-type zinc finger ParBc PF02195.18 PXF43043.1 - 0.068 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 ParB-like nuclease domain DDE_1 PF03184.19 PXF43044.1 - 2.6e-10 40.2 0.7 3.9e-10 39.7 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Glycos_transf_2 PF00535.26 PXF43046.1 - 1.2e-32 113.1 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF43046.1 - 3.5e-13 50.0 0.0 4.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF43046.1 - 7.5e-05 22.3 0.0 9.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PXF43046.1 - 8e-05 22.2 0.2 0.00071 19.1 0.0 2.2 2 1 1 3 3 3 1 Glycosyl transferase family 21 S4_2 PF13275.6 PXF43047.1 - 2.9e-21 75.0 0.6 4.6e-21 74.4 0.6 1.2 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 PXF43047.1 - 7.1e-07 28.9 0.5 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 S4 domain Patatin PF01734.22 PXF43048.1 - 6.3e-13 49.4 0.1 5.2e-11 43.1 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase CIA30 PF08547.12 PXF43049.1 - 4.8e-41 140.4 0.0 6.9e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 PXF43049.1 - 9.1e-18 64.8 0.1 1.2e-08 35.1 0.0 2.9 3 0 0 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 PXF43049.1 - 4.3e-06 26.4 0.0 1.9e-05 24.3 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family SGBP_B_XBD PF18329.1 PXF43049.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Epimerase PF01370.21 PXF43049.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 PXF43049.1 - 0.042 13.3 0.4 0.096 12.1 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 PXF43049.1 - 0.092 12.9 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus EpCAM_N PF18635.1 PXF43049.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Epithelial cell adhesion molecule N-terminal domain CIA30 PF08547.12 PXF43050.1 - 7.4e-40 136.6 0.0 1.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 PXF43050.1 - 2.3e-16 60.2 0.0 6.1e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 NAD(P)H-binding CBM_11 PF03425.13 PXF43050.1 - 0.00045 20.2 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) NmrA PF05368.13 PXF43050.1 - 0.003 17.1 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 PXF43050.1 - 0.036 13.5 0.1 0.096 12.1 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.12 PXF43050.1 - 0.045 12.9 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 PXF43050.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Skp1_POZ PF03931.15 PXF43051.1 - 1.1e-08 35.1 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Methyltransf_21 PF05050.12 PXF43052.1 - 0.00015 21.9 0.5 0.0048 16.9 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase FkbM domain RrnaAD PF00398.20 PXF43053.1 - 1.4e-48 165.3 0.3 1.8e-48 164.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 PXF43053.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 PXF43053.1 - 0.0074 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 PXF43053.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 PXF43053.1 - 0.033 14.9 0.0 0.16 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 PXF43053.1 - 0.037 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 PXF43053.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 PXF43053.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Malectin PF11721.8 PXF43054.1 - 1.3e-08 35.1 0.1 1.8e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Malectin domain TauE PF01925.19 PXF43055.1 - 5.9e-43 147.2 61.1 1.8e-29 103.0 38.7 1.8 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE KRTAP PF11759.8 PXF43056.1 - 0.00011 22.7 12.9 0.00021 21.8 12.9 1.4 1 0 0 1 1 1 1 Keratin-associated matrix DUF5320 PF17253.2 PXF43056.1 - 0.02 15.9 5.6 0.034 15.2 5.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) AMPK1_CBM PF16561.5 PXF43057.1 - 4.1e-15 55.8 0.0 6.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 PXF43057.1 - 0.0001 22.6 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) MULE PF10551.9 PXF43061.1 - 0.00062 20.1 0.1 0.0017 18.7 0.1 1.7 1 1 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 PXF43061.1 - 0.023 14.4 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Transposase Glyco_transf_34 PF05637.12 PXF43062.1 - 1.3e-09 38.2 6.0 1.2e-05 25.1 0.2 3.2 2 1 1 3 3 3 3 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 PXF43062.1 - 0.0021 17.7 0.1 0.006 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 PXF43062.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF3094 PF11293.8 PXF43062.1 - 0.24 11.1 1.1 0.64 9.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TRM PF02005.16 PXF43064.1 - 7.2e-110 367.7 0.0 9.5e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 PXF43064.1 - 0.00043 20.0 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 PXF43064.1 - 0.061 13.0 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Toprim_3 PF13362.6 PXF43064.1 - 0.12 12.7 0.1 0.37 11.2 0.1 1.8 1 0 0 1 1 1 0 Toprim domain Methyltransf_25 PF13649.6 PXF43064.1 - 0.15 12.7 0.0 0.41 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Chromo PF00385.24 PXF43065.1 - 6.5e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAM176 PF14851.6 PXF43065.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Patched PF02460.18 PXF43066.1 - 1.8e-40 138.8 0.0 2.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 PXF43066.1 - 0.00015 20.8 4.0 0.00018 20.6 4.0 1.1 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.19 PXF43066.1 - 2.8 5.5 9.9 3.6 5.1 9.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Patched PF02460.18 PXF43067.1 - 1.7e-24 86.0 0.0 2.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PXF43067.1 - 1.6e-14 54.0 1.0 2.7e-14 53.3 1.0 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation SMN PF06003.12 PXF43068.1 - 1.2e-07 31.3 10.0 0.026 13.8 0.4 3.7 3 1 1 4 4 4 3 Survival motor neuron protein (SMN) NACHT_N PF17100.5 PXF43068.1 - 0.02 14.8 0.3 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase UTP15_C PF09384.10 PXF43069.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 UTP15 C terminal FANCF PF11107.8 PXF43069.1 - 0.081 12.1 6.2 0.067 12.4 2.3 2.2 1 1 1 2 2 2 0 Fanconi anemia group F protein (FANCF) HORMA PF02301.18 PXF43069.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 HORMA domain MoCF_biosynth PF00994.24 PXF43070.1 - 1.8e-27 95.8 0.3 4.7e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain V-SNARE_C PF12352.8 PXF43071.1 - 2.5e-08 34.1 0.2 2.5e-08 34.1 0.2 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Siah-Interact_N PF09032.11 PXF43071.1 - 0.0062 16.8 0.9 1 9.7 0.2 2.9 2 0 0 2 2 2 1 Siah interacting protein, N terminal CENP-Q PF13094.6 PXF43071.1 - 0.01 16.0 4.4 0.073 13.3 1.5 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V-ATPase_C PF03223.15 PXF43071.1 - 0.078 12.4 0.4 4.6 6.5 0.1 2.7 3 0 0 3 3 3 0 V-ATPase subunit C CDT1_C PF16679.5 PXF43071.1 - 0.22 12.0 4.2 0.38 11.2 0.5 2.6 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CK2S PF15011.6 PXF43071.1 - 0.24 11.3 2.4 0.38 10.6 1.0 1.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate zf-C2H2_4 PF13894.6 PXF43072.1 - 1.3e-10 41.1 37.2 0.0046 17.7 3.4 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF43072.1 - 1.4e-10 41.0 37.9 0.00015 22.0 2.0 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF43072.1 - 6.2e-07 29.6 41.0 0.038 14.4 0.4 5.9 6 0 0 6 6 6 5 Zinc-finger double domain HNH_5 PF14279.6 PXF43072.1 - 0.00019 21.2 9.2 7 6.6 0.3 5.5 5 1 0 5 5 5 2 HNH endonuclease zf-C2H2_3rep PF18868.1 PXF43072.1 - 0.00035 21.2 16.9 0.46 11.2 0.4 4.5 2 1 3 5 5 5 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PXF43072.1 - 0.001 19.3 30.6 0.014 15.7 3.7 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF43072.1 - 0.0089 16.3 24.8 2.5 8.5 1.2 4.6 1 1 3 4 4 4 2 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PXF43072.1 - 0.012 15.7 4.4 0.012 15.7 4.4 3.8 3 1 1 4 4 4 0 Zinc ribbon domain zf-met PF12874.7 PXF43072.1 - 0.047 14.1 23.4 0.91 10.0 1.0 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.14 PXF43072.1 - 0.25 11.6 7.4 0.88 9.8 4.2 2.7 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_15 PF17032.5 PXF43072.1 - 0.42 11.4 15.9 2.8 8.8 2.6 3.2 1 1 2 3 3 3 0 zinc-ribbon family zinc_ribbon_9 PF14369.6 PXF43072.1 - 0.65 10.3 10.1 23 5.4 0.1 5.0 5 0 0 5 5 5 0 zinc-ribbon DUF629 PF04780.12 PXF43072.1 - 7.3 5.0 27.6 2 6.8 9.6 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF629) Mal_decarbox_Al PF16957.5 PXF43073.1 - 0.049 12.0 0.0 0.052 11.9 0.0 1.0 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter DUF917 PF06032.12 PXF43075.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) ALG11_N PF15924.5 PXF43076.1 - 3e-25 89.5 0.3 3.1e-25 89.4 0.3 1.0 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus PhoLip_ATPase_C PF16212.5 PXF43078.1 - 3e-22 79.6 6.7 4.1e-22 79.1 6.7 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 PXF43078.1 - 4.1e-05 24.0 0.1 0.085 13.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase 3HCDH_RFF PF18321.1 PXF43078.1 - 0.024 15.1 0.1 0.13 12.7 0.0 2.2 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain AbiEi_4 PF13338.6 PXF43078.1 - 0.1 12.8 1.0 0.23 11.7 1.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Cation_ATPase PF13246.6 PXF43079.1 - 1.5e-11 44.2 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Gly_kinase PF02595.15 PXF43079.1 - 0.04 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family Sec1 PF00995.23 PXF43080.1 - 1.5e-12 47.6 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Ribosomal_L2_C PF03947.18 PXF43083.1 - 2.6e-24 85.8 1.0 3.2e-24 85.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain ABC_tran PF00005.27 PXF43084.1 - 1.2e-08 35.5 0.0 1.7e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Tex_YqgF PF16921.5 PXF43084.1 - 0.027 14.9 0.1 0.046 14.2 0.1 1.3 1 0 0 1 1 1 0 Tex protein YqgF-like domain SMC_N PF02463.19 PXF43084.1 - 0.043 13.2 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_pol_Rpb5_C PF01191.19 PXF43085.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain NAM-associated PF14303.6 PXF43086.1 - 0.00013 22.8 0.6 0.0002 22.1 0.6 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Amidinotransf PF02274.17 PXF43088.1 - 1.4e-52 178.9 0.0 2.8e-52 177.9 0.0 1.5 1 1 0 1 1 1 1 Amidinotransferase Ribosomal_S3_C PF00189.20 PXF43089.1 - 4.7e-24 84.7 0.4 1.8e-23 82.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 PXF43089.1 - 7.3e-13 48.1 0.2 1.2e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 KH domain NUDIX PF00293.28 PXF43090.1 - 3.4e-16 59.5 0.0 4.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PXF43090.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Cpn60_TCP1 PF00118.24 PXF43091.1 - 3e-157 524.2 6.9 3.6e-157 523.9 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1894 PF08979.11 PXF43091.1 - 0.1 12.9 0.0 0.57 10.6 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) WD40 PF00400.32 PXF43092.1 - 4.7e-14 52.6 15.8 0.00032 21.4 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PXF43092.1 - 1.7e-06 28.2 0.0 3.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex LIME1 PF15332.6 PXF43093.1 - 0.16 11.5 1.4 0.31 10.6 1.4 1.4 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 PRIMA1 PF16101.5 PXF43093.1 - 0.21 11.7 2.1 0.39 10.8 2.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Myb_DNA-binding PF00249.31 PXF43094.1 - 3.4e-12 46.4 0.3 7.1e-12 45.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF43094.1 - 0.00047 20.0 0.2 0.0011 18.9 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PXF43094.1 - 0.043 14.1 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain FAE1_CUT1_RppA PF08392.12 PXF43100.1 - 2e-08 33.9 0.1 2.8e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 PXF43100.1 - 0.06 13.3 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF533 PF04391.12 PXF43101.1 - 0.06 12.9 0.2 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF533) zf_C2H2_10 PF18414.1 PXF43103.1 - 6.7 6.4 6.3 1e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger PGI PF00342.19 PXF43104.1 - 8.1e-207 687.6 0.0 9.3e-207 687.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FlgT_N PF16548.5 PXF43104.1 - 0.43 11.2 2.4 1.2 9.8 2.4 1.7 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain STAT_int PF02865.17 PXF43105.1 - 0.14 12.6 0.2 0.26 11.8 0.2 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain YqaJ PF09588.10 PXF43106.1 - 2.2e-07 31.1 0.1 6.9e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain PAS_8 PF13188.7 PXF43106.1 - 0.0047 16.9 0.1 0.1 12.7 0.0 2.9 3 0 0 3 3 3 1 PAS domain Tnp_zf-ribbon_2 PF13842.6 PXF43106.1 - 0.02 15.7 2.8 0.064 14.1 2.8 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 PXF43106.1 - 3.9 7.9 5.8 0.74 10.2 0.8 2.5 2 0 0 2 2 2 0 C1 domain zf-4CXXC_R1 PF10497.9 PXF43107.1 - 0.12 12.6 6.3 0.22 11.8 6.3 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 STT3 PF02516.14 PXF43108.1 - 2.2e-113 379.8 26.0 1.7e-108 363.7 22.3 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 PXF43108.1 - 0.0042 17.3 16.4 0.0042 17.3 16.4 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Apt1 PF10351.9 PXF43108.1 - 0.092 11.6 2.2 0.12 11.2 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DAG_kinase_N PF14513.6 PXF43108.1 - 0.28 11.4 2.7 0.51 10.5 2.7 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Mucin PF01456.17 PXF43108.1 - 0.37 10.8 9.5 0.71 9.9 9.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 PXF43110.1 - 3.7e-15 55.4 25.1 0.0004 20.7 1.4 6.6 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF43110.1 - 7.1e-11 42.0 27.6 0.096 13.6 1.5 6.6 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF43110.1 - 9.4e-08 32.2 27.4 0.035 14.5 1.3 5.8 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 PXF43110.1 - 2e-05 24.2 14.0 0.068 12.9 0.6 5.0 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-Di19 PF05605.12 PXF43110.1 - 0.00056 20.1 16.4 0.0036 17.6 3.5 4.2 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 PXF43110.1 - 0.0026 18.5 16.8 0.12 13.1 0.7 4.1 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 PXF43110.1 - 0.069 13.5 3.5 0.15 12.4 2.6 2.1 1 1 0 1 1 1 0 C2H2-type zinc ribbon WAC_Acf1_DNA_bd PF10537.9 PXF43110.1 - 0.21 12.1 0.5 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-met PF12874.7 PXF43110.1 - 0.58 10.6 11.9 40 4.8 1.2 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Ta0938 PF11494.8 PXF43110.1 - 3.9 7.8 5.3 5.5 7.3 1.4 2.9 1 1 2 3 3 3 0 Ta0938 Yippee-Mis18 PF03226.14 PXF43110.1 - 4.3 7.6 16.1 8.2 6.7 3.8 4.1 2 1 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Vps36-NZF-N PF16988.5 PXF43110.1 - 5.3 6.5 7.4 4.7 6.7 0.2 2.9 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glyco_hydro_6 PF01341.17 PXF43111.1 - 0.15 11.7 0.0 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 6 CDT1 PF08839.11 PXF43112.1 - 6.7e-20 72.1 0.0 2.7e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 PXF43112.1 - 6.6e-12 45.7 4.9 1.7e-11 44.4 2.9 2.7 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain CC2-LZ PF16516.5 PXF43112.1 - 0.015 15.7 1.1 0.15 12.5 0.0 2.9 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2654 PF10849.8 PXF43112.1 - 4.2 7.6 6.3 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2654) Nop52 PF05997.12 PXF43114.1 - 7.5e-36 123.9 0.9 1.2e-35 123.3 0.6 1.5 1 1 0 1 1 1 1 Nucleolar protein,Nop52 GCP_C_terminal PF04130.13 PXF43115.1 - 2.4e-37 129.1 0.9 4.9e-37 128.1 0.9 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PXF43115.1 - 7.8e-11 42.1 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Abhydrolase_6 PF12697.7 PXF43116.1 - 2.1e-08 35.1 0.7 2.6e-08 34.8 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 PXF43116.1 - 0.0018 17.8 0.7 0.012 15.1 0.7 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Imm32 PF15566.6 PXF43116.1 - 0.08 12.8 0.1 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 32 Palm_thioest PF02089.15 PXF43116.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Sel1 PF08238.12 PXF43118.1 - 0.0075 16.9 0.0 3.5 8.4 0.0 3.4 3 0 0 3 3 3 2 Sel1 repeat DNA_ligase_A_M PF01068.21 PXF43120.1 - 5.1e-63 212.4 0.0 9.2e-63 211.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PXF43120.1 - 8.7e-43 146.6 0.2 1.6e-42 145.8 0.2 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PXF43120.1 - 3.8e-26 91.6 0.0 1.5e-25 89.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 PXF43120.1 - 0.0052 16.8 0.7 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain Presenilin PF01080.17 PXF43120.1 - 0.052 12.3 0.4 0.083 11.6 0.4 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PXF43120.1 - 6.6 5.3 12.4 11 4.6 12.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_M50 PF02163.22 PXF43121.1 - 4.3e-61 206.4 0.3 5.3e-61 206.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 PXF43121.1 - 8.9e-12 44.7 2.4 1.8e-11 43.7 1.7 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PXF43121.1 - 3.1e-09 37.0 0.3 6.6e-09 36.0 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PXF43121.1 - 7.5e-09 35.8 0.2 1.6e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 PXF43121.1 - 0.039 13.9 0.5 0.085 12.8 0.2 1.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF3437 PF11919.8 PXF43121.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) zf-H2C2_2 PF13465.6 PXF43122.1 - 1.2e-05 25.5 5.1 2.2e-05 24.7 1.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 PXF43122.1 - 6.7e-05 23.1 0.6 6.7e-05 23.1 0.6 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF43122.1 - 0.072 14.0 0.5 0.072 14.0 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Spt20 PF12090.8 PXF43122.1 - 0.26 10.9 16.7 0.41 10.2 16.7 1.2 1 0 0 1 1 1 0 Spt20 family zf-C2H2_8 PF15909.5 PXF43122.1 - 0.26 11.6 6.1 0.063 13.6 1.1 2.4 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 PXF43122.1 - 0.64 10.1 2.8 9.3 6.4 0.3 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger Neur_chan_memb PF02932.16 PXF43122.1 - 4 7.4 7.1 7 6.6 7.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 PXF43122.1 - 9.8 4.7 9.0 14 4.2 9.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bromodomain PF00439.25 PXF43123.1 - 2.8e-20 72.2 0.0 5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PXF43123.1 - 3.1e-17 62.5 2.3 7.2e-17 61.3 1.5 2.1 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation CENP-T_C PF15511.6 PXF43123.1 - 0.0099 16.0 0.1 0.93 9.6 0.0 2.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold RNA_pol_Rpb2_4 PF04566.13 PXF43126.1 - 8.5e-05 22.8 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 zf-C2H2 PF00096.26 PXF43127.1 - 2.1e-08 34.2 23.0 0.0005 20.4 1.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF43127.1 - 2.4e-07 31.0 22.0 0.00046 20.8 0.5 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF43127.1 - 0.00029 20.5 7.1 0.13 12.0 0.5 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-BED PF02892.15 PXF43127.1 - 0.0078 16.2 3.4 0.0078 16.2 3.4 3.6 2 2 2 4 4 4 1 BED zinc finger zf-met PF12874.7 PXF43127.1 - 0.0099 16.2 8.0 0.1 13.0 0.0 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-CSL PF05207.13 PXF43127.1 - 0.01 15.5 1.4 0.01 15.5 1.4 1.8 2 0 0 2 2 2 0 CSL zinc finger FYVE PF01363.21 PXF43127.1 - 0.099 12.8 14.6 0.43 10.8 8.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.6 PXF43127.1 - 0.13 12.2 0.5 0.13 12.2 0.5 4.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 PXF43127.1 - 1.3 8.8 18.0 0.37 10.6 0.3 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_10 PF10058.9 PXF43127.1 - 1.4 8.7 6.0 4.7 7.0 2.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Enolase_N PF03952.16 PXF43128.1 - 0.034 14.3 0.6 0.075 13.2 0.6 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain WXG100 PF06013.12 PXF43128.1 - 0.044 14.0 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF43128.1 - 2.2 9.0 11.6 0.72 10.6 5.0 2.7 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Plant_tran PF04827.14 PXF43129.1 - 1.8e-52 177.9 0.0 2.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF43129.1 - 5.1e-13 49.0 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H2-Ydr279 PF09468.10 PXF43129.1 - 0.048 13.8 0.0 0.096 12.9 0.0 1.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain An_peroxidase PF03098.15 PXF43130.1 - 9.6e-120 400.6 0.0 1.2e-119 400.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase HSP20 PF00011.21 PXF43131.1 - 4.5e-11 42.8 0.2 3.5e-10 39.9 0.2 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF43131.1 - 1e-05 25.0 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 PXF43131.1 - 0.00018 21.8 0.0 0.00029 21.2 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain An_peroxidase PF03098.15 PXF43132.1 - 1.1e-119 400.4 0.0 1.4e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase GRP PF07172.11 PXF43132.1 - 0.0003 21.4 1.1 0.00058 20.5 1.1 1.4 1 0 0 1 1 1 1 Glycine rich protein family BRCT_2 PF16589.5 PXF43134.1 - 0.021 15.2 1.0 0.67 10.4 0.0 3.0 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain SprT-like PF10263.9 PXF43136.1 - 1e-20 73.7 0.1 2.3e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 SprT-like family RNF220 PF15926.5 PXF43136.1 - 5.3e-07 29.5 14.7 0.0051 16.5 0.5 3.4 2 1 1 3 3 3 3 E3 ubiquitin-protein ligase RNF220 Prok-RING_4 PF14447.6 PXF43136.1 - 0.0062 16.4 3.7 2.7 7.9 0.1 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 Sgf11 PF08209.11 PXF43136.1 - 0.0082 15.7 12.1 0.029 13.9 0.1 4.7 5 0 0 5 5 5 1 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.12 PXF43136.1 - 0.01 16.1 8.8 3.1 8.2 0.2 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 PXF43136.1 - 0.023 14.6 3.3 12 5.9 0.1 3.7 3 0 0 3 3 3 0 Rad50 zinc hook motif PRP21_like_P PF12230.8 PXF43136.1 - 0.036 13.9 7.7 3.5 7.4 0.1 3.7 3 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Zn-C2H2_12 PF18112.1 PXF43136.1 - 1 9.9 9.1 41 4.7 0.1 4.2 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_7 PF02591.15 PXF43136.1 - 3.8 7.8 6.1 28 5.0 0.2 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain Acetyltransf_1 PF00583.25 PXF43138.1 - 5e-12 46.1 0.1 8.7e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PXF43138.1 - 7.7e-09 35.4 0.0 6.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 PXF43138.1 - 2.1e-07 31.3 0.1 4.9e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF43138.1 - 3.8e-06 26.9 0.0 2.5e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF43138.1 - 0.0028 18.3 0.2 0.0052 17.5 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PXF43138.1 - 0.039 14.0 0.1 9.1 6.4 0.0 2.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 PXF43138.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 PXF43138.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 PXF43139.1 - 4.2e-64 216.4 0.0 6.2e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43139.1 - 4.1e-42 144.2 0.0 6.4e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43139.1 - 0.00038 19.9 0.0 0.022 14.1 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF43139.1 - 0.00097 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 PXF43139.1 - 0.066 13.3 4.3 2.5 8.3 0.1 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 PXF43139.1 - 0.2 10.4 2.0 0.48 9.1 2.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase COX5B PF01215.19 PXF43140.1 - 9.9e-21 73.8 0.0 1.3e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 PXF43140.1 - 6.5e-07 29.3 0.1 2.5e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger domain BHD_3 PF10405.9 PXF43141.1 - 2.5e-21 75.8 0.1 6.2e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 PXF43141.1 - 1.4e-15 56.8 0.4 3.9e-15 55.4 0.4 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 PXF43141.1 - 7.7e-10 38.6 5.6 4.2e-09 36.2 1.2 2.9 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 PXF43141.1 - 1.3e-07 32.1 0.2 4.4e-07 30.3 0.2 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily BHD_2 PF10404.9 PXF43141.1 - 0.0025 18.7 3.2 0.0025 18.7 3.2 4.6 4 2 0 4 4 4 1 Rad4 beta-hairpin domain 2 KCNQ2_u3 PF16642.5 PXF43141.1 - 0.31 12.0 8.2 0.054 14.5 2.0 2.9 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Mito_carr PF00153.27 PXF43142.1 - 1.4e-38 130.7 3.9 6.4e-15 54.9 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MCM PF00493.23 PXF43143.1 - 5e-99 329.9 1.0 1.5e-98 328.4 0.3 2.1 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 PXF43143.1 - 1.6e-35 121.7 0.2 2.7e-35 121.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF43143.1 - 3.6e-25 88.2 1.1 3.6e-25 88.2 1.1 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PXF43143.1 - 5.9e-11 42.9 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PXF43143.1 - 3.2e-05 23.4 0.0 0.00013 21.4 0.0 2.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PXF43143.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PaaX PF07848.12 PXF43143.1 - 0.037 14.3 0.6 0.1 12.9 0.6 1.8 1 0 0 1 1 1 0 PaaX-like protein Sigma54_activat PF00158.26 PXF43143.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-RING_11 PF17123.5 PXF43144.1 - 8.4e-09 35.0 1.1 2.6e-08 33.5 1.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 PXF43144.1 - 1.2e-08 35.2 1.2 1.2e-08 35.2 1.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 PXF43144.1 - 9e-06 25.9 0.6 9e-06 25.9 0.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF43144.1 - 9.7e-06 25.3 1.9 9.7e-06 25.3 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF43144.1 - 1.6e-05 24.5 0.9 3.7e-05 23.3 0.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PXF43144.1 - 3.3e-05 23.8 0.2 7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF43144.1 - 0.0001 22.3 1.1 0.0001 22.3 1.1 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PXF43144.1 - 0.00028 20.7 0.3 0.00028 20.7 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PXF43144.1 - 0.00087 19.4 2.2 0.12 12.6 0.1 3.1 3 0 0 3 3 3 1 FANCL C-terminal domain zf-RING_5 PF14634.6 PXF43144.1 - 0.002 18.0 0.5 0.002 18.0 0.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain RINGv PF12906.7 PXF43144.1 - 0.19 11.9 1.4 0.52 10.5 1.4 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PXF43144.1 - 0.36 10.9 4.6 0.64 10.1 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger Prok-RING_4 PF14447.6 PXF43144.1 - 0.54 10.2 5.9 0.15 11.9 1.2 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 PhzC-PhzF PF02567.16 PXF43145.1 - 1.2e-47 162.7 0.0 1.5e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Glyoxalase PF00903.25 PXF43146.1 - 4.6e-22 78.6 0.0 1.9e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF43146.1 - 7.9e-14 51.9 0.0 8.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PXF43146.1 - 2e-05 24.8 0.1 2 8.5 0.0 4.1 1 1 3 4 4 4 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 PXF43146.1 - 0.00015 22.5 0.0 1.2 9.9 0.0 2.7 3 0 0 3 3 3 2 Glyoxalase-like domain TxDE PF18711.1 PXF43146.1 - 0.014 15.5 0.1 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 Toxoflavin-degrading enzyme Glyco_hydro_63 PF03200.16 PXF43147.1 - 5.2e-132 441.1 0.0 2.9e-130 435.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 PXF43147.1 - 6.5e-23 82.0 0.0 1.2e-22 81.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 PXF43147.1 - 0.00091 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Trehalase ATP-synt_ab PF00006.25 PXF43149.1 - 1.1e-105 352.0 0.0 1.6e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PXF43149.1 - 1.7e-45 153.8 0.0 2.8e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 PXF43149.1 - 2e-13 50.7 0.9 2e-13 50.7 0.9 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DnaJ PF00226.31 PXF43150.1 - 1.9e-08 34.3 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain MORN_2 PF07661.13 PXF43150.1 - 2.8e-06 26.9 2.7 0.012 15.8 0.0 4.6 5 0 0 5 5 5 2 MORN repeat variant Rubis-subs-bind PF09273.11 PXF43151.1 - 2.7e-09 37.8 0.2 5.5e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 PXF43151.1 - 3.2e-08 34.2 0.0 9e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 SET domain SprT-like PF10263.9 PXF43152.1 - 2.2e-25 88.7 0.3 4.1e-25 87.8 0.3 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 PXF43152.1 - 1.7e-08 34.2 6.8 3.4e-08 33.3 6.8 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 PXF43152.1 - 0.01 15.9 0.6 0.027 14.6 0.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Peptidase_M50B PF13398.6 PXF43152.1 - 0.077 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like DnaJ_CXXCXGXG PF00684.19 PXF43153.1 - 0.00013 22.2 11.8 0.00025 21.4 11.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PXF43153.1 - 0.028 14.4 4.3 0.028 14.4 4.3 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Prim_Zn_Ribbon PF08273.12 PXF43153.1 - 0.07 13.4 0.5 0.07 13.4 0.5 3.2 1 1 2 3 3 3 0 Zinc-binding domain of primase-helicase zf-C6H2 PF15801.5 PXF43153.1 - 0.19 12.0 6.1 4.4 7.7 0.7 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-RRN7 PF11781.8 PXF43153.1 - 1.5 8.6 10.2 7.1 6.4 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FBPase PF00316.20 PXF43154.1 - 1.6e-30 106.0 0.2 2.4e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 PXF43154.1 - 0.0055 16.3 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family TIMP PF00965.17 PXF43155.1 - 0.00099 19.0 0.2 0.0027 17.6 0.2 1.6 1 1 0 1 1 1 1 Tissue inhibitor of metalloproteinase DEP PF00610.21 PXF43156.1 - 1.5e-29 101.8 0.1 2.6e-15 56.2 0.2 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.32 PXF43157.1 - 0.00039 21.2 4.7 0.013 16.3 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Fibrinogen_aC PF12160.8 PXF43157.1 - 0.28 11.0 3.9 0.43 10.5 2.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha C domain NLE PF08154.12 PXF43158.1 - 2.6e-11 43.9 0.1 3.9e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 PXF43158.1 - 0.073 14.0 0.7 2.7 9.0 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Actin PF00022.19 PXF43159.1 - 1.9e-49 168.4 0.0 2.2e-31 108.9 0.0 2.8 2 1 0 2 2 2 2 Actin FAE1_CUT1_RppA PF08392.12 PXF43160.1 - 1e-115 386.0 0.0 1.5e-115 385.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 PXF43160.1 - 6e-12 45.6 0.0 1.9e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 PXF43160.1 - 1.2e-09 38.4 0.0 2.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 PXF43160.1 - 0.00053 19.5 0.0 0.0009 18.7 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.10 PXF43160.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KH_6 PF15985.5 PXF43163.1 - 4.8e-12 46.0 0.5 9.4e-12 45.1 0.5 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 PXF43163.1 - 2.2e-06 27.5 0.1 5.6e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Methyltransf_28 PF02636.17 PXF43164.1 - 6.3e-51 173.5 0.0 8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase AA_permease_2 PF13520.6 PXF43165.1 - 0.06 12.2 0.0 0.063 12.1 0.0 1.0 1 0 0 1 1 1 0 Amino acid permease COX7C PF02935.16 PXF43165.1 - 0.27 11.5 2.2 0.43 10.9 2.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc PAC3 PF10178.9 PXF43166.1 - 1.4e-19 70.0 0.2 1.8e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DUF4203 PF13886.6 PXF43168.1 - 2.1e-07 30.8 27.9 5.8e-07 29.4 27.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) CAP_GLY PF01302.25 PXF43169.1 - 1.6e-18 66.5 0.6 2.4e-18 65.9 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 PXF43169.1 - 2.2e-13 50.4 0.0 3.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Sod_Cu PF00080.20 PXF43170.1 - 3.3e-32 111.6 0.9 4.3e-32 111.2 0.9 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Glyco_tranf_2_3 PF13641.6 PXF43171.1 - 4.3e-24 85.7 0.0 7.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF43171.1 - 4.5e-23 81.9 0.0 1.4e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 PXF43171.1 - 1.9e-15 56.4 1.0 7.2e-09 34.7 1.2 3.2 1 1 1 3 3 3 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 PXF43171.1 - 1e-11 45.1 3.1 2.2e-11 44.0 1.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 PXF43171.1 - 3.6e-09 36.3 0.0 3.5e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 HXXEE PF13787.6 PXF43171.1 - 0.034 15.0 0.0 0.034 15.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif Glyco_tranf_2_2 PF10111.9 PXF43171.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CrgA PF06781.12 PXF43171.1 - 0.52 10.4 4.0 0.29 11.2 0.2 2.5 2 0 0 2 2 2 0 Cell division protein CrgA YbaB_DNA_bd PF02575.16 PXF43173.1 - 7.1e-14 51.8 0.0 9.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family SelR PF01641.18 PXF43174.1 - 1.4e-44 151.1 0.5 1.7e-44 150.8 0.5 1.1 1 0 0 1 1 1 1 SelR domain Ribosomal_L37e PF01907.19 PXF43174.1 - 0.0025 17.9 3.5 0.03 14.5 0.9 2.4 2 0 0 2 2 2 1 Ribosomal protein L37e zf-RRN7 PF11781.8 PXF43174.1 - 0.016 14.9 3.2 0.03 14.0 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 PXF43174.1 - 0.022 14.2 0.7 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Endonuclease_7 PF02945.15 PXF43174.1 - 0.047 13.6 0.5 0.12 12.3 0.5 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII zf-Mss51 PF13824.6 PXF43174.1 - 0.13 12.4 2.7 0.14 12.3 0.3 2.2 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 PXF43174.1 - 0.21 11.6 2.4 0.52 10.4 1.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF2318 PF10080.9 PXF43174.1 - 0.23 11.6 1.8 0.43 10.7 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zf-ribbon_3 PF13248.6 PXF43174.1 - 1.2 8.7 4.9 13 5.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DUF4203 PF13886.6 PXF43176.1 - 1e-21 77.5 27.8 1.4e-21 77.1 27.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DNA_photolyase PF00875.18 PXF43177.1 - 6.4e-43 146.6 0.0 9.9e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Synaptobrevin PF00957.21 PXF43179.1 - 2.7e-14 52.7 0.6 4.4e-14 52.0 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PXF43179.1 - 9e-14 51.3 0.0 2.4e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Regulated-SNARE-like domain ETC_C1_NDUFA5 PF04716.14 PXF43180.1 - 7.3e-24 83.4 0.1 1.1e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region zf-RING_UBOX PF13445.6 PXF43183.1 - 1e-05 25.4 4.3 1e-05 25.4 4.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF43183.1 - 3.7e-05 23.5 4.2 3.7e-05 23.5 4.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF43183.1 - 0.00041 20.6 15.6 0.0029 17.9 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PXF43183.1 - 0.0016 18.3 9.0 0.0037 17.2 8.2 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PXF43183.1 - 0.0019 17.9 1.6 0.0047 16.6 1.6 1.7 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF43183.1 - 0.0064 16.3 4.4 0.0064 16.3 4.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 PXF43183.1 - 1.3 9.0 4.8 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 PXF43183.1 - 5.1 7.0 12.5 0.21 11.4 4.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PXF43183.1 - 8 6.4 17.2 4 7.4 7.0 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Evr1_Alr PF04777.13 PXF43184.1 - 2.1e-27 95.5 0.5 4.3e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family DAHP_snth_FXD PF18152.1 PXF43186.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain NAD_Gly3P_dh_C PF07479.14 PXF43187.1 - 1.1e-41 142.5 0.1 1.6e-41 141.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 PXF43187.1 - 3.3e-39 134.4 0.0 5.6e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 PXF43187.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PXF43187.1 - 0.00027 21.5 0.0 0.0014 19.2 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 PXF43187.1 - 0.0015 19.0 0.0 0.014 15.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF43187.1 - 0.0036 16.6 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 PXF43187.1 - 0.0078 16.5 0.0 0.12 12.6 0.0 2.6 3 0 0 3 3 3 1 TrkA-N domain 3HCDH_N PF02737.18 PXF43187.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 PXF43188.1 - 6.5e-32 110.9 0.0 7.4e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Pyr_redox_2 PF07992.14 PXF43189.1 - 9.8e-46 156.3 0.0 1.7e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF43189.1 - 1.7e-22 80.1 0.0 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 PXF43189.1 - 1.1e-15 57.5 0.0 2.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 PXF43189.1 - 9.7e-15 54.9 0.2 1.5e-12 47.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF43189.1 - 2.6e-05 23.1 0.2 0.0089 14.8 0.2 2.6 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 PXF43189.1 - 3.3e-05 23.4 0.5 3.3e-05 23.4 0.5 3.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase Glutaredoxin PF00462.24 PXF43189.1 - 6.9e-05 23.0 0.0 0.00088 19.4 0.0 2.6 2 1 1 3 3 3 1 Glutaredoxin GIDA PF01134.22 PXF43189.1 - 0.0001 21.5 7.6 0.013 14.6 0.1 3.9 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PXF43189.1 - 0.00025 20.3 5.2 0.00061 19.0 0.6 3.0 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 PXF43189.1 - 0.00053 19.2 0.1 0.077 12.1 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 PXF43189.1 - 0.0013 18.0 1.6 0.004 16.4 0.1 2.4 3 0 0 3 3 3 1 Thi4 family Thioredoxin_2 PF13098.6 PXF43189.1 - 0.0028 18.1 0.0 0.059 13.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain NAD_binding_8 PF13450.6 PXF43189.1 - 0.0038 17.4 0.0 0.0038 17.4 0.0 3.5 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Thioredoxin_7 PF13899.6 PXF43189.1 - 0.0076 16.4 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like DAO PF01266.24 PXF43189.1 - 0.015 14.9 4.8 0.96 9.0 0.8 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PXF43189.1 - 0.069 13.6 0.3 2.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 PXF43189.1 - 0.082 11.7 0.5 0.32 9.8 0.1 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Thioredoxin_3 PF13192.6 PXF43189.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain FAD_binding_3 PF01494.19 PXF43189.1 - 0.11 11.7 1.5 0.56 9.4 0.3 2.5 3 0 0 3 3 3 0 FAD binding domain Thioredoxin_4 PF13462.6 PXF43189.1 - 0.12 12.5 0.6 0.48 10.6 0.0 2.1 2 1 1 3 3 2 0 Thioredoxin DUF836 PF05768.14 PXF43189.1 - 0.13 12.7 0.1 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) T2SSE_N PF05157.15 PXF43190.1 - 0.12 12.6 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Pkinase PF00069.25 PXF43191.1 - 1.7e-66 224.3 0.0 2.3e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43191.1 - 1.2e-38 132.9 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43191.1 - 4.7e-05 22.9 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 PXF43191.1 - 0.00029 21.3 0.2 0.0011 19.5 0.0 2.0 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 PXF43191.1 - 0.0073 15.1 0.8 0.014 14.2 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 PXF43191.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PXF43191.1 - 0.052 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 RIO1 family NPL4 PF05021.15 PXF43191.1 - 0.094 12.1 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 NPL4 family DKCLD PF08068.12 PXF43192.1 - 1.3e-31 108.5 3.8 5.5e-31 106.4 0.6 2.8 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 PXF43192.1 - 6.7e-22 78.5 0.6 2.2e-19 70.3 0.6 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PXF43192.1 - 2.6e-21 75.5 0.3 5e-21 74.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 PXF43192.1 - 2e-19 69.3 3.1 4.7e-19 68.1 3.1 1.7 1 0 0 1 1 1 1 PUA domain Coilin_N PF15862.5 PXF43192.1 - 4.2e-05 23.4 6.5 6.7e-05 22.7 6.5 1.4 1 0 0 1 1 1 1 Coilin N-terminus GAGA_bind PF06217.12 PXF43192.1 - 1 9.6 10.8 1.4 9.2 10.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 PXF43192.1 - 3.2 7.8 30.1 5.6 7.0 30.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Alanine_zipper PF11839.8 PXF43193.1 - 0.045 14.1 11.8 0.1 13.0 1.5 3.1 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein PhoU PF01895.19 PXF43193.1 - 0.05 14.1 6.1 3.7 8.1 1.2 2.8 2 1 0 2 2 2 0 PhoU domain PNPase PF03726.14 PXF43193.1 - 1.1 9.9 6.6 0.27 11.8 0.3 3.0 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WXG100 PF06013.12 PXF43193.1 - 1.1 9.6 9.8 8.1 6.8 2.9 4.1 3 1 0 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 PXF43193.1 - 1.3 9.5 7.7 0.82 10.2 0.2 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PXF43193.1 - 3 7.9 8.3 1.8 8.6 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Muted PF14942.6 PXF43193.1 - 9.8 6.5 15.5 1.4 9.3 7.6 3.0 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Methyltransf_25 PF13649.6 PXF43194.1 - 3.4e-18 66.1 0.0 7.6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF43194.1 - 1.4e-16 60.9 0.0 2.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF43194.1 - 5.4e-14 52.3 0.0 8.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43194.1 - 3.9e-09 37.1 0.0 1.1e-08 35.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF43194.1 - 1.2e-08 35.0 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF43194.1 - 3.1e-08 33.2 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PXF43194.1 - 3.1e-05 23.6 0.0 9.5e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 PXF43194.1 - 0.00042 20.1 0.0 0.001 18.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_8 PF05148.15 PXF43194.1 - 0.0008 19.3 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 PXF43194.1 - 0.0057 15.3 0.0 0.015 13.9 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 PXF43194.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DDE_Tnp_1 PF01609.21 PXF43196.1 - 0.056 13.1 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain KH_1 PF00013.29 PXF43197.1 - 4.7e-55 183.3 16.9 3.5e-14 52.4 0.3 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 PXF43197.1 - 2.3e-13 49.8 0.9 2.8e-05 23.9 0.0 4.5 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 PXF43197.1 - 3e-11 43.0 12.7 0.005 16.6 0.5 4.9 5 1 1 6 6 6 4 KH domain MOEP19 PF16005.5 PXF43197.1 - 4.7e-05 23.3 0.0 3.5 7.7 0.0 3.3 3 0 0 3 3 3 3 KH-like RNA-binding domain KH_5 PF13184.6 PXF43197.1 - 0.038 14.1 7.3 16 5.7 0.2 4.1 4 0 0 4 4 4 0 NusA-like KH domain SLS PF14611.6 PXF43197.1 - 0.48 10.2 2.7 51 3.6 1.8 3.3 1 1 2 3 3 3 0 Mitochondrial inner-membrane-bound regulator TPR_12 PF13424.6 PXF43198.1 - 8.8e-07 29.1 11.7 0.0024 18.1 0.3 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF43198.1 - 0.00016 21.5 7.4 0.0052 16.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF43198.1 - 0.00054 19.8 3.2 5.7 7.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF43198.1 - 0.0017 18.1 0.3 0.35 10.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF43198.1 - 0.0036 17.8 7.2 2.1 8.9 0.0 5.0 1 1 4 5 5 5 2 Tetratricopeptide repeat bZIP_Maf PF03131.17 PXF43198.1 - 0.011 16.2 1.5 0.011 16.2 1.5 3.4 3 0 0 3 3 3 0 bZIP Maf transcription factor PHD PF00628.29 PXF43199.1 - 2.6e-07 30.4 5.2 4.6e-07 29.6 5.2 1.4 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 PXF43199.1 - 2 8.6 5.0 5.2 7.3 5.0 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 PXF43199.1 - 2.4 8.3 5.5 5.9 7.1 5.5 1.7 1 0 0 1 1 1 0 PHD-finger PsbQ PF05757.11 PXF43199.1 - 5.9 6.6 11.9 25 4.5 11.9 2.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF3681 PF12442.8 PXF43201.1 - 0.11 13.0 0.4 0.11 13.0 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3681) Chromo PF00385.24 PXF43202.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Sec1 PF00995.23 PXF43204.1 - 1.5e-80 272.1 0.0 1.8e-80 271.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4472 PF14739.6 PXF43204.1 - 7.4 7.4 8.0 44 4.9 0.5 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) FAD_binding_3 PF01494.19 PXF43205.1 - 8.8e-27 94.2 0.0 1.2e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PXF43205.1 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 PXF43205.1 - 0.00012 21.2 0.0 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 PXF43205.1 - 0.00016 22.1 0.0 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF43205.1 - 0.00022 20.6 0.0 0.0017 17.6 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF43205.1 - 0.00065 19.4 0.0 0.015 14.9 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PXF43205.1 - 0.0033 16.3 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 PXF43205.1 - 0.0041 15.9 0.0 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 PXF43205.1 - 0.0047 16.1 0.0 0.0072 15.5 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 PXF43205.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 PXF43205.1 - 0.038 14.5 0.0 0.089 13.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 PXF43205.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PXF43205.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PXF43205.1 - 0.16 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain eRF1_2 PF03464.15 PXF43206.1 - 4.6e-46 156.4 0.0 7.6e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PXF43206.1 - 7.6e-34 116.6 0.4 1.5e-33 115.7 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 PXF43206.1 - 4.2e-19 68.8 0.0 4.9e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 PXF43206.1 - 1.7e-08 34.8 0.0 2.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 PXF43206.1 - 1e-07 32.3 0.0 2.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 PHF5 PF03660.14 PXF43207.1 - 5.6e-48 161.5 13.2 6.2e-48 161.3 13.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 PXF43207.1 - 0.11 10.4 8.3 0.11 10.3 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 PXF43207.1 - 1.4 9.3 17.0 0.11 12.8 3.0 2.7 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 PXF43207.1 - 2.1 8.4 15.4 2.4 8.3 1.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon XPG_N PF00752.17 PXF43208.1 - 8e-27 93.7 0.0 6.4e-26 90.8 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 PXF43208.1 - 3e-25 88.4 0.0 1.3e-24 86.4 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 PXF43208.1 - 0.047 14.3 0.3 0.29 11.8 0.0 2.5 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold MCM PF00493.23 PXF43209.1 - 1.4e-101 338.3 0.2 2.1e-101 337.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PXF43209.1 - 2.5e-36 124.3 0.0 4.6e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF43209.1 - 3.4e-26 91.5 0.6 7.2e-26 90.4 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PXF43209.1 - 5.3e-12 46.2 0.1 1.5e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM6_C PF18263.1 PXF43209.1 - 5.4e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 PXF43209.1 - 2.7e-07 30.2 0.0 2.3e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PXF43209.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PXF43209.1 - 0.0036 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 PXF43209.1 - 0.011 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zn-ribbon_8 PF09723.10 PXF43209.1 - 1.2 9.3 3.2 2.6 8.3 3.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain CarbpepA_inh PF02977.15 PXF43210.1 - 0.06 13.2 14.7 0.39 10.5 1.8 2.5 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor DX PF01666.17 PXF43210.1 - 0.12 12.9 21.4 0.14 12.7 5.5 3.2 2 1 1 3 3 3 0 DX module Mito_carr PF00153.27 PXF43212.1 - 9.4e-33 112.0 3.1 5.8e-15 55.0 0.1 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF43212.1 - 0.084 12.0 0.3 5.4 6.1 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Profilin PF00235.19 PXF43215.1 - 7.1e-27 94.2 0.1 8.3e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 Profilin PPDK_N PF01326.19 PXF43215.1 - 0.055 12.7 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RabGAP-TBC PF00566.18 PXF43216.1 - 7.4e-37 127.1 0.0 1.1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1658 PF07871.11 PXF43216.1 - 0.14 12.2 5.6 0.49 10.4 5.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) DUF4653 PF15546.6 PXF43216.1 - 1.7 8.2 0.0 1.7 8.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4653) NDUFA12 PF05071.16 PXF43217.1 - 7.7e-25 87.6 2.6 9.9e-25 87.2 2.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Polyketide_cyc2 PF10604.9 PXF43218.1 - 6.3e-12 46.0 0.0 7.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PXF43218.1 - 0.0023 18.1 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-C3HC4_2 PF13923.6 PXF43219.1 - 1.6e-08 34.3 12.2 2.9e-08 33.4 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF43219.1 - 6.9e-07 29.2 11.8 1.5e-06 28.1 11.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PXF43219.1 - 1.4e-05 25.1 12.1 3.1e-05 24.0 12.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PXF43219.1 - 2.2e-05 24.2 12.2 4.5e-05 23.2 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF43219.1 - 7.1e-05 23.1 14.2 0.00016 21.9 14.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PXF43219.1 - 0.00014 21.7 11.3 0.00031 20.6 11.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF43219.1 - 0.00016 21.4 13.8 0.00027 20.7 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PXF43219.1 - 0.018 14.9 7.2 0.034 14.0 7.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PXF43219.1 - 0.68 9.8 16.4 10 6.1 0.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PXF43219.1 - 1.2 9.5 12.2 5.9 7.3 12.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 PXF43219.1 - 3.5 7.8 9.6 8 6.7 9.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 PXF43219.1 - 3.6 7.5 8.7 7 6.6 8.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ABC1 PF03109.16 PXF43220.1 - 5.6e-32 110.4 0.2 1.2e-31 109.3 0.2 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PXF43220.1 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF43220.1 - 0.0078 16.2 3.0 0.009 16.0 0.1 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 PXF43220.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Atx10homo_assoc PF09759.9 PXF43221.1 - 2.8e-06 27.2 4.0 8.3e-06 25.7 0.1 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 PXF43221.1 - 0.00059 19.8 3.1 0.0086 16.1 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CDC24_OB1 PF17246.2 PXF43222.1 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 DUF2514 PF10721.9 PXF43222.1 - 0.013 15.5 2.7 0.013 15.5 2.7 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) TFIIA PF03153.13 PXF43223.1 - 1.8 8.5 10.6 2.5 8.0 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MscL PF01741.18 PXF43224.1 - 1.8e-19 70.2 1.5 2.4e-19 69.8 1.5 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 PXF43224.1 - 0.0078 16.2 0.7 0.014 15.4 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 PXF43224.1 - 0.027 13.9 2.8 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 PXF43224.1 - 0.06 13.1 1.5 0.13 12.0 1.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain UPF0239 PF06783.11 PXF43224.1 - 0.063 13.5 0.4 0.11 12.7 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) UPF0547 PF10571.9 PXF43224.1 - 0.12 12.4 1.1 0.24 11.5 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 FtsX PF02687.21 PXF43224.1 - 0.2 12.1 3.6 0.31 11.5 3.6 1.3 1 0 0 1 1 1 0 FtsX-like permease family DNA_ligase_ZBD PF03119.16 PXF43224.1 - 0.7 10.0 4.7 0.34 11.0 0.8 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.12 PXF43224.1 - 1.2 9.2 5.0 16 5.5 0.1 3.1 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger DUF1963 PF09234.10 PXF43225.1 - 4.2e-06 27.4 0.0 1e-05 26.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) Mito_carr PF00153.27 PXF43227.1 - 1.6e-36 124.1 6.5 5.1e-17 61.6 0.1 4.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PetG PF02529.15 PXF43227.1 - 0.16 11.8 1.2 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 E_Pc_C PF06752.12 PXF43227.1 - 8.3 6.4 7.5 15 5.6 7.5 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Aminotran_5 PF00266.19 PXF43228.1 - 1.7e-33 116.1 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ephrin_rec_like PF07699.13 PXF43231.1 - 1.6e-31 107.8 133.2 3e-07 30.1 6.3 15.7 4 4 9 14 14 14 13 Putative ephrin-receptor like NCD3G PF07562.14 PXF43231.1 - 3.1e-10 39.9 111.2 0.019 14.9 3.0 14.5 6 6 11 17 17 17 14 Nine Cysteines Domain of family 3 GPCR Glyco_hydro_16 PF00722.21 PXF43233.1 - 3.8e-26 91.6 3.7 5.6e-26 91.1 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3421 PF11901.8 PXF43234.1 - 2.7e-37 127.2 0.3 9.1e-24 83.7 0.0 3.9 2 1 2 4 4 4 4 Protein of unknown function (DUF3421) Peptidase_C14 PF00656.22 PXF43234.1 - 1.3e-36 126.9 0.0 1.7e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Lig_chan PF00060.26 PXF43238.1 - 0.0081 16.0 0.0 0.57 10.0 0.0 2.4 2 0 0 2 2 2 2 Ligand-gated ion channel SBP_bac_3 PF00497.20 PXF43238.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 OAD_gamma PF04277.13 PXF43239.1 - 5.4 7.7 10.6 0.71 10.5 5.0 2.2 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Lactamase_B PF00753.27 PXF43240.1 - 0.0072 16.4 0.1 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF43240.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LRR_4 PF12799.7 PXF43241.1 - 0.0051 17.2 0.1 6.2 7.4 0.2 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Endostatin PF06482.11 PXF43241.1 - 0.028 13.9 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DDE_Tnp_4 PF13359.6 PXF43242.1 - 2.9e-07 30.3 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease L27_2 PF09045.10 PXF43243.1 - 0.026 14.5 0.8 0.11 12.5 0.5 2.1 2 0 0 2 2 2 0 L27_2 Chromo PF00385.24 PXF43244.1 - 7.1e-05 22.6 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Amidohydro_3 PF07969.11 PXF43245.1 - 1.2e-62 213.0 0.0 1.5e-62 212.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PXF43245.1 - 6.1e-12 45.5 0.0 2.6e-08 33.6 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family HTH_16 PF12645.7 PXF43245.1 - 0.12 12.5 0.8 0.51 10.4 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain SBP_bac_3 PF00497.20 PXF43246.1 - 0.00047 19.7 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PXF43246.1 - 0.0032 17.3 0.0 0.0065 16.3 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel Phage_holin_Dp1 PF16938.5 PXF43246.1 - 0.25 11.6 1.6 2.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Putative phage holin Dp-1 VWA_2 PF13519.6 PXF43248.1 - 1.3e-09 38.7 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PXF43248.1 - 1e-07 32.4 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF43248.1 - 3.5e-06 27.1 0.0 5.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Kelch_1 PF01344.25 PXF43252.1 - 7.8e-14 51.0 0.4 0.00046 19.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 PXF43252.1 - 1.3e-09 38.1 0.0 0.03 14.6 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF43252.1 - 2.1e-08 34.2 0.1 0.051 13.9 0.0 4.5 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 PXF43252.1 - 5e-07 29.6 0.0 0.02 14.9 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 PXF43252.1 - 0.00018 21.3 0.4 5.9 7.0 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Lig_chan PF00060.26 PXF43253.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PXF43253.1 - 0.0054 16.2 0.0 0.075 12.4 0.0 2.2 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Ntox47 PF15540.6 PXF43255.1 - 1.8e-22 79.8 0.6 3.6e-22 78.8 0.6 1.5 1 0 0 1 1 1 1 Bacterial toxin 47 CBM60 PF16841.5 PXF43255.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Tudor_3 PF18115.1 PXF43256.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Exonuc_VII_L PF02601.15 PXF43256.1 - 0.16 11.5 6.5 0.37 10.3 6.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit TUDOR_5 PF18359.1 PXF43256.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 GAS PF13851.6 PXF43256.1 - 0.68 9.3 4.8 1.1 8.5 4.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.11 PXF43256.1 - 0.84 9.6 3.4 1.2 9.2 1.1 2.2 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF948 PF06103.11 PXF43256.1 - 1.6 9.0 2.9 7.9 6.8 2.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LemA PF04011.12 PXF43257.1 - 0.081 12.8 0.7 0.44 10.4 0.2 2.4 2 0 0 2 2 2 0 LemA family Gti1_Pac2 PF09729.9 PXF43257.1 - 0.52 10.4 4.1 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family V-set PF07686.17 PXF43258.1 - 0.033 14.4 0.3 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Immunoglobulin V-set domain Big_7 PF17957.1 PXF43259.1 - 0.052 14.3 0.0 0.3 11.9 0.0 2.4 1 1 1 2 2 2 0 Bacterial Ig domain Fn3_assoc PF13287.6 PXF43259.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Fn3 associated Sporozoite_P67 PF05642.11 PXF43260.1 - 0.17 9.9 3.7 0.23 9.5 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WWE PF02825.20 PXF43261.1 - 4.4e-11 43.2 0.1 9.4e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 WWE domain ART PF01129.18 PXF43261.1 - 6.8e-08 32.1 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 PXF43261.1 - 0.00021 20.7 0.1 0.0086 15.4 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosyltransferase exoenzyme DUF3388 PF11868.8 PXF43265.1 - 0.97 8.7 2.1 2.9 7.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3388) His_Phos_2 PF00328.22 PXF43267.1 - 0.019 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Herpes_UL49_5 PF05702.11 PXF43267.1 - 0.039 14.0 0.1 0.085 13.0 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Prominin PF05478.11 PXF43267.1 - 0.1 10.5 0.2 3.1 5.6 0.1 2.0 2 0 0 2 2 2 0 Prominin Ank_2 PF12796.7 PXF43268.1 - 1.8e-29 102.1 0.0 1.5e-16 60.8 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF43268.1 - 2.1e-22 78.9 0.1 3.2e-10 40.1 0.0 4.4 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PXF43268.1 - 3.3e-21 75.4 0.0 2.1e-10 40.9 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PXF43268.1 - 9.9e-21 73.2 0.0 4.5e-06 26.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PXF43268.1 - 2.5e-20 70.4 0.0 1.3e-05 25.2 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Pro_isomerase PF00160.21 PXF43269.1 - 9.5e-49 165.7 0.3 1.1e-48 165.5 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tudor_2 PF18104.1 PXF43270.1 - 0.69 9.6 2.5 5.1 6.9 0.3 3.0 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain FMO-like PF00743.19 PXF43273.1 - 4.9e-47 160.5 0.0 1.3e-46 159.2 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PXF43273.1 - 7.1e-14 51.8 0.0 6.7e-13 48.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF43273.1 - 1.5e-13 50.7 0.0 1.8e-12 47.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PXF43273.1 - 4.8e-11 42.4 0.1 2e-09 37.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 PXF43273.1 - 7.2e-08 32.6 0.0 6.3e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PXF43273.1 - 1e-07 32.1 0.1 4.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PXF43273.1 - 4.7e-07 29.5 0.4 9.3e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 PXF43273.1 - 5.2e-06 26.3 1.6 7.2e-05 22.5 0.7 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PXF43273.1 - 5.7e-05 22.6 0.0 0.0028 17.0 0.0 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PXF43273.1 - 0.00045 20.7 0.4 0.4 11.3 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF43273.1 - 0.0018 17.6 0.0 0.004 16.4 0.0 1.6 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 PXF43273.1 - 0.005 16.2 1.2 0.085 12.1 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PXF43273.1 - 0.0087 14.8 1.6 0.041 12.6 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 PXF43273.1 - 0.0091 15.1 0.3 0.02 14.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 PXF43273.1 - 0.059 13.8 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 PXF43273.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 PXF43273.1 - 0.21 10.6 0.6 0.89 8.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-C2H2 PF00096.26 PXF43276.1 - 3e-06 27.4 12.9 0.00012 22.3 5.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF43276.1 - 0.00015 22.3 12.1 0.061 14.2 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF43276.1 - 0.0095 16.6 2.2 0.15 12.7 2.6 2.3 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats Hint PF01079.20 PXF43277.1 - 1.2e-22 80.5 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Hint module EF-hand_7 PF13499.6 PXF43279.1 - 0.0029 18.0 0.3 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair ubiquitin PF00240.23 PXF43280.1 - 5.3e-09 35.7 0.0 9.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PXF43280.1 - 2.6e-06 27.5 0.0 7.4e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PXF43280.1 - 2.8e-05 24.6 0.1 0.00011 22.7 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Transformer PF06495.11 PXF43280.1 - 0.069 13.2 0.2 0.069 13.2 0.2 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein Rad60-SLD PF11976.8 PXF43280.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PseudoU_synth_2 PF00849.22 PXF43281.1 - 2.2e-19 70.1 0.0 3.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PXF43281.1 - 0.0032 17.2 0.1 0.0066 16.1 0.1 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 PXF43281.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 S4 domain OB_NTP_bind PF07717.16 PXF43282.1 - 5.9e-20 71.4 0.0 1.5e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PXF43282.1 - 1.3e-16 60.8 0.0 1e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 PXF43282.1 - 9.6e-14 51.5 0.1 1.9e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43282.1 - 3.1e-13 50.0 0.0 9e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PXF43282.1 - 6.4e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF43282.1 - 0.00029 20.0 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 PXF43282.1 - 0.00047 20.4 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PXF43282.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 PXF43282.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF43282.1 - 0.022 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PXF43282.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 PXF43282.1 - 0.057 13.4 0.0 0.41 10.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF43282.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 PXF43282.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PXF43282.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region YqaJ PF09588.10 PXF43284.1 - 1.4e-05 25.3 0.0 0.00026 21.2 0.0 2.4 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain Phospholip_B PF04916.13 PXF43284.1 - 0.0044 15.7 0.0 0.7 8.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase B DDE_Tnp_1 PF01609.21 PXF43284.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain Chromo PF00385.24 PXF43285.1 - 0.0049 16.7 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pex14_N PF04695.13 PXF43286.1 - 0.4 11.3 8.4 0.58 10.8 8.4 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pol_alpha_B_N PF08418.10 PXF43286.1 - 1.1 9.2 12.1 1.3 8.9 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PA26 PF04636.13 PXF43286.1 - 1.3 7.9 5.6 1.4 7.7 5.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDK5_activator PF03261.15 PXF43286.1 - 1.5 8.3 6.2 1.5 8.3 6.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3381 PF11861.8 PXF43286.1 - 1.6 8.5 14.5 2.7 7.8 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) GREB1 PF15782.5 PXF43286.1 - 5.3 4.0 8.9 5.8 3.9 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Herpes_UL25 PF01499.16 PXF43286.1 - 5.9 5.3 8.8 6.2 5.2 8.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family SAPS PF04499.15 PXF43286.1 - 7.3 5.2 8.1 8.2 5.1 8.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPT2 PF08243.11 PXF43287.1 - 0.011 16.2 38.8 0.011 16.2 38.8 3.5 2 1 1 3 3 3 0 SPT2 chromatin protein Med3 PF11593.8 PXF43287.1 - 1.9 7.6 5.8 3 6.9 5.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3446 PF11928.8 PXF43287.1 - 5.5 7.4 12.3 19 5.7 0.3 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain AICARFT_IMPCHas PF01808.18 PXF43288.1 - 1.9e-114 382.1 4.1 2.5e-114 381.7 4.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 PXF43288.1 - 1.7e-23 82.6 0.0 4.3e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain CoA_binding_2 PF13380.6 PXF43288.1 - 0.33 11.5 3.0 9.8 6.7 0.1 3.2 3 2 0 3 3 3 0 CoA binding domain TerC PF03741.16 PXF43290.1 - 1.6e-43 148.5 10.0 2.5e-43 147.9 10.0 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family DDDD PF10161.9 PXF43290.1 - 0.38 10.5 2.6 0.33 10.7 0.5 2.1 2 0 0 2 2 2 0 Putative mitochondrial precursor protein YjeF_N PF03853.15 PXF43291.1 - 1.4e-39 135.7 0.1 1.8e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF1656 PF07869.12 PXF43291.1 - 0.0066 16.4 1.0 0.017 15.2 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) Tnp_zf-ribbon_2 PF13842.6 PXF43292.1 - 0.0016 19.2 1.7 0.005 17.6 1.5 2.0 1 1 1 2 2 2 1 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.16 PXF43292.1 - 0.056 13.8 2.3 0.11 12.9 0.9 2.1 2 0 0 2 2 2 0 C1 domain LANC_like PF05147.13 PXF43292.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein YqaJ PF09588.10 PXF43293.1 - 5.8e-07 29.8 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain PAS_8 PF13188.7 PXF43293.1 - 0.0045 17.0 0.2 0.12 12.5 0.0 3.1 4 0 0 4 4 4 1 PAS domain AAA_16 PF13191.6 PXF43293.1 - 0.082 13.3 0.1 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DDE_Tnp_1 PF01609.21 PXF43293.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain PP2C PF00481.21 PXF43294.1 - 5e-57 193.5 0.1 7.1e-54 183.1 0.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C TPMT PF05724.11 PXF43295.1 - 9.2e-30 103.9 0.0 1.3e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 PXF43295.1 - 5.8e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF43295.1 - 5.2e-06 27.0 0.1 8.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43295.1 - 5e-05 24.0 0.0 7.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF43295.1 - 0.00022 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain HMG_CoA_synt_N PF01154.17 PXF43296.1 - 1.8e-78 262.4 0.0 2.6e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 PXF43296.1 - 7.2e-74 248.9 0.0 9e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 PXF43296.1 - 0.029 14.5 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal KIF1B PF12423.8 PXF43296.1 - 0.035 14.5 0.2 0.097 13.1 0.2 1.8 1 0 0 1 1 1 0 Kinesin protein 1B ATP-synt_D PF01813.17 PXF43297.1 - 7e-65 218.6 0.5 1e-64 218.0 0.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D GTP_EFTU PF00009.27 PXF43298.1 - 1.5e-39 135.6 0.1 3.5e-39 134.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PXF43298.1 - 2.8e-12 46.9 0.5 2.8e-12 46.9 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 PXF43298.1 - 6.1e-07 29.5 0.1 3.1e-06 27.3 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase HBS1_N PF08938.10 PXF43298.1 - 0.00027 21.2 6.7 0.0016 18.7 7.8 1.7 2 0 0 2 2 2 1 HBS1 N-terminus SRPRB PF09439.10 PXF43298.1 - 0.002 17.6 0.0 0.078 12.4 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PXF43298.1 - 0.0021 18.0 2.8 0.11 12.4 1.5 2.8 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 PXF43298.1 - 0.015 14.9 0.0 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 PXF43298.1 - 0.092 12.3 0.1 1.7 8.1 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 PXF43299.1 - 6.4e-114 376.0 0.0 4.6e-29 101.2 0.0 7.8 7 0 0 7 7 7 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PXF43299.1 - 1.2e-27 96.3 0.0 5.5e-09 36.0 0.0 6.5 6 1 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PXF43299.1 - 8.4e-25 87.7 0.2 0.00079 19.9 0.0 6.8 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 PXF43299.1 - 5.3e-24 84.5 14.2 1.2e-08 35.1 0.4 6.0 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_7 PF12775.7 PXF43299.1 - 1.6e-20 73.4 0.8 9.9e-05 21.9 0.0 5.7 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA_16 PF13191.6 PXF43299.1 - 2.5e-20 73.6 4.5 0.013 15.8 0.0 7.6 7 0 0 7 7 7 5 AAA ATPase domain AAA_lid_5 PF17865.1 PXF43299.1 - 9.4e-16 57.8 0.0 1.2e-14 54.3 0.0 2.9 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_22 PF13401.6 PXF43299.1 - 1.2e-15 58.0 3.4 0.0035 17.6 0.0 7.8 8 0 0 8 8 6 3 AAA domain AAA_14 PF13173.6 PXF43299.1 - 4.1e-15 56.0 0.0 0.32 11.0 0.0 7.2 7 0 0 7 7 7 4 AAA domain AAA_18 PF13238.6 PXF43299.1 - 2.9e-14 53.7 1.0 0.35 11.4 0.0 6.0 5 0 0 5 5 5 4 AAA domain ABC_tran PF00005.27 PXF43299.1 - 3.2e-13 50.4 4.7 0.0039 17.7 0.0 6.0 6 0 0 6 6 5 3 ABC transporter Dynein_heavy PF03028.15 PXF43299.1 - 7.3e-13 48.7 0.0 0.0014 18.7 0.0 5.9 5 1 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 PXF43299.1 - 1.4e-12 47.7 0.0 0.36 10.5 0.0 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_6 PF12774.7 PXF43299.1 - 1e-11 44.4 0.1 0.13 11.2 0.0 7.2 8 2 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 PXF43299.1 - 1.2e-10 41.5 0.0 0.036 13.8 0.0 5.8 7 0 0 7 7 6 1 AAA domain T2SSE PF00437.20 PXF43299.1 - 2.5e-10 39.9 3.8 0.12 11.4 0.1 5.3 5 0 0 5 5 5 3 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PXF43299.1 - 7.3e-10 39.0 0.3 0.57 10.1 0.0 4.8 4 0 0 4 4 4 2 RsgA GTPase RNA_helicase PF00910.22 PXF43299.1 - 9.5e-10 38.8 1.9 2.1 8.7 0.0 6.3 6 0 0 6 6 5 1 RNA helicase AAA_29 PF13555.6 PXF43299.1 - 1.9e-09 37.1 2.4 0.42 10.4 0.0 5.6 5 0 0 5 5 5 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 PXF43299.1 - 2.1e-09 37.1 1.3 1.1 8.7 0.0 7.4 7 1 1 8 8 8 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PXF43299.1 - 2.2e-09 37.4 5.0 0.18 11.8 0.1 5.8 6 0 0 6 6 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 PXF43299.1 - 4.7e-09 36.1 2.1 0.2 11.2 0.0 5.7 6 0 0 6 6 5 2 AAA domain NACHT PF05729.12 PXF43299.1 - 3.1e-08 33.7 0.3 2.1 8.3 0.0 5.1 5 0 0 5 5 4 2 NACHT domain AAA_33 PF13671.6 PXF43299.1 - 3.3e-08 33.8 2.5 0.14 12.3 0.0 6.0 6 0 0 6 6 5 1 AAA domain Rad17 PF03215.15 PXF43299.1 - 3.7e-08 33.5 1.4 0.11 12.4 0.0 5.2 4 0 0 4 4 4 1 Rad17 P-loop domain DUF815 PF05673.13 PXF43299.1 - 4.6e-08 32.5 0.5 0.23 10.6 0.1 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PXF43299.1 - 1.5e-07 30.9 0.1 1.4 8.1 0.0 5.3 5 0 0 5 5 5 1 Zeta toxin IstB_IS21 PF01695.17 PXF43299.1 - 1.8e-07 31.1 0.1 3 7.5 0.0 5.1 5 0 0 5 5 4 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 PXF43299.1 - 3.7e-07 30.1 0.0 5.8 6.6 0.0 5.1 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase AAA_8 PF12780.7 PXF43299.1 - 5.1e-07 29.3 0.5 0.11 11.9 0.1 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region D4 AAA_28 PF13521.6 PXF43299.1 - 1.1e-06 29.1 5.1 0.97 9.7 0.0 5.5 5 0 0 5 5 5 1 AAA domain SRP54 PF00448.22 PXF43299.1 - 2e-06 27.6 1.5 1.5 8.4 0.0 4.7 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PXF43299.1 - 7.1e-06 26.7 16.2 0.65 10.5 0.0 6.2 6 0 0 6 6 5 3 AAA domain PduV-EutP PF10662.9 PXF43299.1 - 4.3e-05 23.3 1.8 4 7.2 0.1 4.5 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 PXF43299.1 - 6.9e-05 22.9 0.4 15 5.7 0.0 4.9 4 0 0 4 4 4 0 50S ribosome-binding GTPase DEAD PF00270.29 PXF43299.1 - 7.8e-05 22.5 0.5 7.1 6.4 0.0 5.0 5 0 0 5 5 5 0 DEAD/DEAH box helicase AAA_2 PF07724.14 PXF43299.1 - 9.1e-05 22.6 0.0 0.99 9.5 0.0 4.8 5 0 0 5 5 4 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 PXF43299.1 - 0.00012 21.9 1.3 9.8 5.8 0.0 5.3 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 PXF43299.1 - 0.00018 21.8 8.9 10 6.4 0.0 6.1 8 0 0 8 8 4 0 AAA domain DAP3 PF10236.9 PXF43299.1 - 0.00019 20.7 0.4 0.67 9.1 0.0 3.9 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 VWA PF00092.28 PXF43299.1 - 0.0002 21.7 0.1 0.00058 20.2 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain TrwB_AAD_bind PF10412.9 PXF43299.1 - 0.0003 19.8 1.1 0.95 8.3 0.0 3.4 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain RuvB_N PF05496.12 PXF43299.1 - 0.0006 19.6 2.0 7.5 6.3 0.0 5.1 5 0 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 PXF43299.1 - 0.0006 19.9 6.7 4.3 7.3 0.0 4.4 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit Roc PF08477.13 PXF43299.1 - 0.00068 19.8 1.0 4.1 7.6 0.0 4.4 5 0 0 5 5 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 PXF43299.1 - 0.00087 18.8 0.1 2.4 7.5 0.0 4.9 5 0 0 5 5 4 1 Bacterial TniB protein NTPase_1 PF03266.15 PXF43299.1 - 0.0013 18.7 0.4 27 4.6 0.0 4.4 4 0 0 4 4 4 0 NTPase ATPase_2 PF01637.18 PXF43299.1 - 0.0032 17.4 0.2 18 5.2 0.0 4.7 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 PXF43299.1 - 0.0047 17.0 0.0 8.1 6.6 0.0 4.6 4 0 0 4 4 4 0 Sigma-54 interaction domain CPT PF07931.12 PXF43299.1 - 0.0077 16.1 0.1 18 5.1 0.0 4.4 4 0 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.10 PXF43299.1 - 0.008 15.6 1.4 13 5.2 0.0 4.4 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 PXF43299.1 - 0.0099 15.7 2.6 3.2 7.5 0.0 4.2 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein cobW PF02492.19 PXF43299.1 - 0.012 15.2 2.0 6.9 6.2 0.0 4.2 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 PXF43299.1 - 0.017 14.5 0.7 0.84 8.9 0.1 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 PXF43299.1 - 0.039 13.9 0.4 23 4.9 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.13 PXF43299.1 - 0.056 12.6 1.4 5.5 6.1 0.0 3.9 5 0 0 5 5 4 0 TIP49 P-loop domain dNK PF01712.19 PXF43299.1 - 0.063 13.1 1.2 5.8 6.7 0.0 3.9 4 0 0 4 4 4 0 Deoxynucleoside kinase ATP-synt_ab PF00006.25 PXF43299.1 - 0.12 12.1 0.0 46 3.6 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.21 PXF43299.1 - 0.15 11.7 0.1 41 3.8 0.0 3.8 4 0 0 4 4 4 0 Guanylate kinase Ploopntkinase3 PF18751.1 PXF43299.1 - 0.18 11.7 0.1 40 4.1 0.0 3.6 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 PXF43299.1 - 0.18 11.8 1.0 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_11 PF13086.6 PXF43299.1 - 1.3 8.7 15.6 3.5 7.3 0.0 5.7 6 1 0 6 6 4 0 AAA domain UFC1 PF08694.11 PXF43301.1 - 1.1e-79 265.5 0.1 1.2e-79 265.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 PXF43301.1 - 0.0017 18.0 0.2 0.003 17.2 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PXF43301.1 - 0.0063 16.8 0.6 0.013 15.8 0.5 1.5 1 1 1 2 2 2 1 RWD domain PI3_PI4_kinase PF00454.27 PXF43302.1 - 1.2e-34 120.2 0.2 4e-32 112.0 0.2 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PXF43302.1 - 1.1e-08 34.7 0.1 3.5e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 PXF43302.1 - 0.0029 17.0 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) MatC_N PF07158.11 PXF43302.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Ribosomal_S15 PF00312.22 PXF43303.1 - 8.2e-30 102.9 0.5 1.1e-29 102.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 TMF_TATA_bd PF12325.8 PXF43304.1 - 0.0023 18.1 6.4 0.0023 18.1 6.4 13.5 6 4 7 13 13 13 1 TATA element modulatory factor 1 TATA binding UvrA_DNA-bind PF17755.1 PXF43304.1 - 0.51 10.7 3.9 3.2 8.1 0.4 3.2 3 0 0 3 3 3 0 UvrA DNA-binding domain K_channel_TID PF07941.11 PXF43304.1 - 7.8 7.0 7.1 31 5.1 0.3 3.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Exo_endo_phos PF03372.23 PXF43305.1 - 4.6e-24 85.2 0.6 6.4e-24 84.8 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PXF43305.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF5027 PF16430.5 PXF43305.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) SVIP PF15811.5 PXF43306.1 - 0.062 13.8 9.1 0.24 11.9 9.1 1.9 1 1 0 1 1 1 0 Small VCP/p97-interacting protein Pkinase PF00069.25 PXF43307.1 - 6.2e-63 212.6 0.0 2.7e-54 184.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43307.1 - 4.4e-33 114.7 0.0 2.5e-30 105.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PXF43307.1 - 7.9e-06 25.4 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PXF43307.1 - 3.6e-05 23.8 0.6 0.00054 20.0 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF43307.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF43307.1 - 0.036 13.6 0.0 0.087 12.4 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PXF43307.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain LRR_9 PF14580.6 PXF43308.1 - 3e-42 144.1 0.3 4.1e-42 143.6 0.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PXF43308.1 - 1.9e-17 62.8 7.9 4.4e-10 39.2 0.4 2.8 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PXF43308.1 - 4.9e-11 42.7 6.6 1.2e-06 28.8 0.3 3.6 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PXF43308.1 - 0.029 14.9 2.4 5.9 7.9 0.2 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 PXF43308.1 - 0.87 9.8 12.1 54 4.2 0.0 5.6 7 0 0 7 7 7 0 Leucine Rich repeat CobN-Mg_chel PF02514.16 PXF43309.1 - 0 1141.5 0.0 0 1141.2 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 PXF43309.1 - 2.8e-50 170.6 0.4 5.8e-50 169.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) ATE_C PF04377.15 PXF43310.1 - 1.6e-50 171.2 3.0 2.9e-50 170.3 3.0 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Arg_tRNA_synt_N PF03485.16 PXF43310.1 - 0.00065 20.2 0.0 0.002 18.6 0.0 1.9 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Acetyltransf_6 PF13480.7 PXF43310.1 - 0.04 14.1 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_11 PF08241.12 PXF43311.1 - 3.1e-20 72.6 0.0 4.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF43311.1 - 3.4e-18 66.1 0.0 5.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF43311.1 - 1.5e-14 53.9 0.0 3e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF43311.1 - 7e-14 51.9 0.0 9.2e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43311.1 - 4e-13 49.9 0.0 7.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF43311.1 - 1.6e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PXF43311.1 - 0.004 16.5 0.1 0.01 15.2 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 PXF43311.1 - 0.0051 15.9 0.0 0.0074 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.15 PXF43311.1 - 0.0068 15.7 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 PXF43311.1 - 0.083 12.4 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain TPR_9 PF13371.6 PXF43311.1 - 0.18 12.0 0.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ADK PF00406.22 PXF43312.1 - 1.2e-25 90.4 0.0 8.3e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 PXF43312.1 - 2.9e-12 47.2 0.0 1.9e-07 31.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PXF43312.1 - 8.7e-06 26.3 0.2 0.0031 18.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PXF43312.1 - 0.00086 19.5 0.2 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2285 PF10074.9 PXF43312.1 - 0.036 14.7 0.6 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) MeaB PF03308.16 PXF43312.1 - 0.043 12.8 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hydin_ADK PF17213.3 PXF43312.1 - 0.058 13.7 0.0 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CAP_N PF01213.19 PXF43312.1 - 0.068 12.6 2.8 0.1 12.1 2.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_28 PF13521.6 PXF43312.1 - 0.083 13.1 0.4 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 PXF43312.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ANAPC4_WD40 PF12894.7 PXF43313.1 - 0.0034 17.6 0.0 9.4 6.6 0.0 4.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF43313.1 - 0.019 15.8 2.6 41 5.3 0.5 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat TLD PF07534.16 PXF43315.1 - 8e-38 129.8 0.3 1.2e-37 129.2 0.3 1.3 1 0 0 1 1 1 1 TLD DUF4201 PF13870.6 PXF43315.1 - 0.16 11.7 0.5 0.42 10.3 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 PXF43315.1 - 0.18 11.8 2.5 0.59 10.2 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.6 PXF43315.1 - 2.3 8.4 10.1 30 4.8 10.1 2.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Zip PF02535.22 PXF43316.1 - 6.2e-43 147.3 3.4 8e-43 146.9 3.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 PXF43316.1 - 0.21 11.1 1.6 9.3 5.7 0.7 2.7 2 1 0 2 2 2 0 E1-E2 ATPase Wzy_C PF04932.15 PXF43316.1 - 0.47 10.1 4.2 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 O-Antigen ligase DUF2721 PF11026.8 PXF43316.1 - 7.5 6.5 11.8 0.57 10.1 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) 2OG-FeII_Oxy_2 PF13532.6 PXF43317.1 - 5.6e-28 98.5 0.0 6.6e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mnd1 PF03962.15 PXF43318.1 - 3.5e-27 94.5 0.1 8e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 PXF43318.1 - 1.2e-18 66.9 0.6 1.2e-18 66.9 0.6 2.4 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 PXF43318.1 - 0.00013 22.3 1.8 0.00013 22.3 1.8 1.6 1 1 1 2 2 2 1 Penicillinase repressor Nckap1 PF09735.9 PXF43318.1 - 0.0029 15.6 2.3 0.0035 15.4 2.3 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein FUR PF01475.19 PXF43318.1 - 0.0094 16.1 2.9 0.022 14.9 1.0 2.3 1 1 1 2 2 2 1 Ferric uptake regulator family DUF3450 PF11932.8 PXF43318.1 - 0.055 12.8 6.2 0.14 11.4 6.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 PXF43318.1 - 0.12 10.2 4.8 0.14 10.1 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 PXF43318.1 - 0.26 10.6 3.0 0.33 10.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAA_hydro_N_2 PF18288.1 PXF43318.1 - 0.29 11.6 1.8 0.82 10.1 0.6 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF5595 PF18077.1 PXF43318.1 - 0.34 11.0 9.2 0.3 11.2 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) MbeD_MobD PF04899.12 PXF43318.1 - 0.43 10.7 4.9 36 4.6 4.9 2.5 1 1 0 1 1 1 0 MbeD/MobD like TMF_TATA_bd PF12325.8 PXF43318.1 - 0.61 10.3 13.7 0.17 12.1 9.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EF-G-binding_N PF07299.11 PXF43318.1 - 0.64 10.6 6.3 12 6.5 4.5 2.6 1 1 1 2 2 2 0 Elongation factor G-binding protein, N-terminal Phage_GPO PF05929.11 PXF43318.1 - 0.66 9.6 6.3 0.86 9.2 6.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NusB PF01029.18 PXF43318.1 - 1.4 9.2 5.7 0.72 10.1 3.4 1.7 2 0 0 2 2 2 0 NusB family Acetyltransf_11 PF13720.6 PXF43318.1 - 2.7 8.5 6.3 7.3 7.1 2.0 3.1 3 2 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CENP-H PF05837.12 PXF43318.1 - 3.9 7.9 10.7 2 8.9 8.1 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 PXF43318.1 - 5.6 6.8 13.8 0.38 10.5 3.5 2.6 2 1 1 3 3 3 0 Septum formation initiator DUF4337 PF14235.6 PXF43318.1 - 5.9 7.0 7.0 8 6.5 6.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4097 PF13349.6 PXF43319.1 - 2.4e-08 33.7 1.2 1.8e-06 27.5 1.2 2.6 1 1 0 1 1 1 1 Putative adhesin Fil_haemagg_2 PF13332.6 PXF43319.1 - 0.04 14.0 2.0 0.18 12.0 2.0 2.2 1 1 0 1 1 1 0 Hemagglutinin repeat DUF3540 PF12059.8 PXF43319.1 - 0.063 13.1 0.2 3.2 7.5 0.2 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) PseudoU_synth_2 PF00849.22 PXF43320.1 - 2.4e-09 37.5 0.0 5.5e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PXF43320.1 - 1.6e-06 27.7 0.0 4.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 S4 domain Methyltransf_23 PF13489.6 PXF43321.1 - 8.4e-19 68.0 0.0 1.1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF43321.1 - 4.5e-18 65.7 0.0 7.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF43321.1 - 1.9e-17 63.8 0.0 3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF43321.1 - 1.9e-12 47.0 0.0 1.1e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF43321.1 - 6.2e-12 45.6 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43321.1 - 9.5e-11 42.3 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PXF43321.1 - 0.00099 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 PXF43321.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 PXF43321.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 PXF43321.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain GIT_CC PF16559.5 PXF43322.1 - 0.018 14.9 0.2 0.018 14.9 0.2 3.7 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4472 PF14739.6 PXF43322.1 - 0.038 14.7 1.0 0.038 14.7 1.0 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 PXF43322.1 - 0.59 9.4 7.2 1 8.6 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 PXF43322.1 - 0.69 10.5 15.8 4.4 7.9 0.8 3.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal KASH_CCD PF14662.6 PXF43322.1 - 0.85 9.4 18.6 0.37 10.6 12.2 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 PXF43322.1 - 0.93 9.6 18.0 0.028 14.5 11.3 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Shugoshin_N PF07558.11 PXF43322.1 - 0.94 9.4 4.6 26 4.8 0.1 3.6 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region V_ATPase_I PF01496.19 PXF43322.1 - 4.4 5.1 8.6 7.2 4.4 8.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PXF43322.1 - 5.5 7.7 15.3 5.4 7.7 2.0 3.8 1 1 2 3 3 3 0 Initiation control protein YabA Arm PF00514.23 PXF43323.1 - 4.6e-24 83.7 10.8 0.015 15.3 0.0 9.3 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 PXF43323.1 - 6e-20 71.1 5.2 5e-06 26.4 0.0 5.7 2 2 5 7 7 7 5 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 PXF43323.1 - 4.6e-05 23.0 0.4 0.091 12.2 0.0 3.0 2 1 2 4 4 4 3 Armadillo-like PUL PF08324.11 PXF43323.1 - 0.00031 20.1 6.8 0.0036 16.6 1.8 3.4 3 1 1 4 4 4 1 PUL domain DUF3361 PF11841.8 PXF43323.1 - 0.0065 16.4 4.0 0.32 10.9 0.1 3.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3361) Tti2 PF10521.9 PXF43323.1 - 0.031 13.8 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Tti2 family IL31 PF15209.6 PXF43323.1 - 0.068 12.9 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Interleukin 31 V-ATPase_H_N PF03224.14 PXF43323.1 - 0.14 11.4 0.1 0.76 9.0 0.0 2.0 1 1 0 2 2 2 0 V-ATPase subunit H SICA_alpha PF12887.7 PXF43323.1 - 0.4 10.5 3.9 1 9.2 0.1 2.9 2 0 0 2 2 2 0 SICA extracellular alpha domain Glyco_transf_90 PF05686.12 PXF43324.1 - 1.2e-31 110.1 0.4 1.2e-31 110.1 0.4 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 90 Med19 PF10278.9 PXF43324.1 - 1.7 8.5 45.0 4.2 7.3 18.9 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Red1 PF07964.11 PXF43324.1 - 9.2 4.4 46.0 13 3.9 46.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Cyt-b5 PF00173.28 PXF43325.1 - 1.2e-20 73.4 0.0 1.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SKG6 PF08693.10 PXF43325.1 - 0.0016 17.8 2.4 0.0025 17.2 2.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3188 PF11384.8 PXF43325.1 - 0.049 13.3 0.9 0.1 12.3 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) p450 PF00067.22 PXF43326.1 - 1.7e-64 218.3 0.0 2.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 PXF43327.1 - 6.4e-38 130.6 0.0 1.1e-21 77.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43327.1 - 2.4e-12 46.7 0.0 8.7e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PXF43327.1 - 0.0099 15.8 0.1 0.49 10.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF43327.1 - 0.29 9.8 1.8 0.47 9.2 0.1 1.9 1 1 1 2 2 2 0 Fungal protein kinase Rrn6 PF10214.9 PXF43327.1 - 3.2 6.1 6.5 4.3 5.7 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RSN1_7TM PF02714.15 PXF43328.1 - 3.9e-28 98.5 15.4 3.9e-28 98.5 15.4 2.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PXF43328.1 - 6.7e-07 29.2 0.2 6.7e-07 29.2 0.2 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PXF43328.1 - 1.1e-05 25.8 0.0 0.0068 16.7 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF3493 PF11998.8 PXF43329.1 - 6e-15 55.2 0.2 1.1e-14 54.3 0.2 1.4 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 CENP-R PF06729.12 PXF43329.1 - 0.0032 17.4 1.0 0.015 15.3 1.4 1.8 2 0 0 2 2 2 1 Kinetochore component, CENP-R tRNA_U5-meth_tr PF05958.11 PXF43330.1 - 3.6e-16 59.1 0.0 1.2e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PXF43330.1 - 2.8e-11 43.4 0.1 5.5e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF43330.1 - 9.1e-08 32.7 0.1 3.5e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PXF43330.1 - 4.8e-06 26.2 0.1 9.8e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 PXF43330.1 - 1.5e-05 24.6 0.1 2.8e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 PXF43330.1 - 8.7e-05 22.0 0.2 0.00016 21.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PXF43330.1 - 0.00017 21.6 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF43330.1 - 0.00019 21.1 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PXF43330.1 - 0.00041 20.2 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 PXF43330.1 - 0.00064 19.2 0.1 0.0016 17.9 0.1 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 PXF43330.1 - 0.001 19.0 0.3 0.0029 17.6 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 PXF43330.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 PXF43330.1 - 0.0027 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PXF43330.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 PXF43330.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 DNA methylase Methyltransf_11 PF08241.12 PXF43330.1 - 0.038 14.6 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PXF43330.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43330.1 - 0.12 13.1 0.1 0.42 11.4 0.1 1.9 2 0 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.18 PXF43330.1 - 0.67 9.6 2.5 1.7 8.3 0.7 2.3 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Spc7 PF08317.11 PXF43331.1 - 0.025 13.4 4.1 0.042 12.7 0.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein GlnE PF03710.15 PXF43331.1 - 0.045 13.2 7.5 0.032 13.7 1.1 2.4 2 1 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase CwsA PF10814.8 PXF43331.1 - 0.09 13.0 3.2 0.1 12.8 0.6 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA ABC_tran_CTD PF16326.5 PXF43331.1 - 0.15 12.3 2.1 3.1 8.1 0.1 3.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 PXF43331.1 - 0.76 10.1 3.9 1.4 9.3 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.18 PXF43331.1 - 1.2 8.4 5.1 12 5.1 0.5 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 PXF43331.1 - 1.2 9.8 9.9 1.5 9.4 0.6 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 PXF43331.1 - 3.8 6.8 10.5 3.4 6.9 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4570 PF15134.6 PXF43331.1 - 4.2 7.4 7.6 0.31 11.1 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) Jnk-SapK_ap_N PF09744.9 PXF43331.1 - 10 6.4 11.0 2.4 8.3 0.6 2.5 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 HLH PF00010.26 PXF43335.1 - 3.5e-09 36.5 0.4 7.8e-09 35.4 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4661 PF15576.6 PXF43335.1 - 0.0051 16.8 0.3 0.0072 16.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4661) Gon7 PF08738.10 PXF43335.1 - 0.67 10.1 5.3 4 7.6 0.2 2.2 2 0 0 2 2 2 0 Gon7 family DUF89 PF01937.19 PXF43336.1 - 3.9e-77 259.6 0.0 4.8e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Gcd10p PF04189.13 PXF43337.1 - 5.1e-56 190.0 0.0 7.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family zf-RING_14 PF17978.1 PXF43337.1 - 0.047 14.1 0.3 0.094 13.1 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 PXF43338.1 - 1.2e-71 236.4 3.8 2.1e-17 62.7 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF43338.1 - 7.5e-08 32.0 0.0 0.026 14.1 0.0 4.6 4 1 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PXF43338.1 - 2.8e-05 24.2 0.0 0.19 12.0 0.0 3.4 3 0 0 3 3 3 2 RRM-like domain RRM_occluded PF16842.5 PXF43338.1 - 0.00093 19.0 0.0 6.7 6.7 0.0 3.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 PXF43338.1 - 0.011 15.7 9.9 4 7.5 0.2 4.6 4 1 0 4 4 4 0 RNA binding motif TetR_C_14 PF17754.1 PXF43338.1 - 0.034 14.1 1.9 0.086 12.8 1.9 1.7 1 0 0 1 1 1 0 MftR C-terminal domain Nup35_RRM_2 PF14605.6 PXF43338.1 - 0.081 12.9 0.0 11 6.2 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 PXF43338.1 - 7.7 6.7 18.3 2.7 8.2 0.1 6.5 4 3 4 8 8 8 0 Cytosolic domain of 10TM putative phosphate transporter UPF0176_N PF17773.1 PXF43339.1 - 9.9e-18 64.3 0.0 2.3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 PXF43339.1 - 2.2e-10 40.8 4.6 4.7e-10 39.7 4.7 1.6 1 1 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 PXF43339.1 - 7.3e-07 29.7 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Tnp_zf-ribbon_2 PF13842.6 PXF43339.1 - 0.58 11.0 5.7 1.3 9.9 5.7 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon STAS_2 PF13466.6 PXF43341.1 - 0.033 14.5 0.2 0.063 13.6 0.2 1.4 1 0 0 1 1 1 0 STAS domain Mitoc_mL59 PF18126.1 PXF43341.1 - 0.068 13.5 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 PsbQ PF05757.11 PXF43342.1 - 0.00023 21.0 8.6 0.0017 18.2 8.6 1.9 1 1 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) Syntaxin-6_N PF09177.11 PXF43342.1 - 0.087 13.4 0.4 0.31 11.6 0.4 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Thioredoxin PF00085.20 PXF43343.1 - 1.9e-14 53.5 0.0 1.1e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 PXF43343.1 - 5.5e-05 23.6 0.1 0.015 15.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 PXF43343.1 - 0.0035 16.7 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 PXF43343.1 - 0.071 12.9 0.2 24 4.6 0.0 2.9 3 0 0 3 3 3 0 F plasmid transfer operon protein HEAT_2 PF13646.6 PXF43344.1 - 0.0027 18.1 9.0 0.12 12.7 0.7 3.7 1 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 PXF43344.1 - 0.021 15.5 1.3 2.8 8.9 0.1 3.8 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat BAR_3 PF16746.5 PXF43344.1 - 0.062 13.0 6.9 0.018 14.8 3.9 1.6 2 0 0 2 2 2 0 BAR domain of APPL family DUF2267 PF10025.9 PXF43344.1 - 1.1 9.5 9.9 0.13 12.6 2.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Peptidase_M3_N PF08439.10 PXF43346.1 - 0.12 12.6 0.9 0.25 11.7 0.9 1.5 1 0 0 1 1 1 0 Oligopeptidase F bZIP_2 PF07716.15 PXF43346.1 - 2.5 8.2 8.3 8.4 6.6 8.3 1.8 1 1 0 1 1 1 0 Basic region leucine zipper AAA_12 PF13087.6 PXF43348.1 - 2.4e-54 184.0 0.0 4.8e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PXF43348.1 - 2.7e-46 158.5 1.3 1.9e-27 96.7 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 PXF43348.1 - 1.7e-12 47.5 0.0 1.1e-11 44.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF43348.1 - 5.1e-09 36.6 0.1 1.6e-08 35.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 PXF43348.1 - 3.7e-05 23.3 0.0 0.05 13.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein UvrD_C_2 PF13538.6 PXF43348.1 - 0.00086 19.1 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 PXF43348.1 - 0.0014 18.3 0.0 0.0037 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 PXF43348.1 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 PXF43348.1 - 0.0095 15.7 0.2 0.077 12.8 0.2 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PXF43348.1 - 0.018 15.3 0.0 0.3 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PXF43348.1 - 0.018 15.0 0.1 0.09 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PXF43348.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PXF43348.1 - 0.021 15.3 0.0 0.057 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 PXF43348.1 - 0.022 13.9 0.0 0.072 12.2 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase DUF2075 PF09848.9 PXF43348.1 - 0.03 13.6 0.1 0.076 12.2 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 PXF43348.1 - 0.031 13.6 0.0 0.079 12.3 0.0 1.6 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 PXF43348.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 PXF43348.1 - 0.085 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PXF43348.1 - 0.17 12.3 0.0 0.54 10.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DnaJ_CXXCXGXG PF00684.19 PXF43351.1 - 0.001 19.4 6.8 0.0056 17.0 7.1 2.1 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 PXF43351.1 - 0.14 12.1 10.3 3.7 7.6 0.4 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_S8e PF01201.22 PXF43352.1 - 1.9e-48 164.1 2.6 1.9e-48 164.1 2.6 1.6 1 1 1 2 2 2 1 Ribosomal protein S8e Taq-exonuc PF09281.10 PXF43352.1 - 0.036 14.1 0.2 0.068 13.2 0.2 1.5 1 0 0 1 1 1 0 Taq polymerase, exonuclease OmpH PF03938.14 PXF43353.1 - 0.00046 20.5 6.7 0.09 13.1 0.9 2.3 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) BAR PF03114.18 PXF43353.1 - 0.0011 18.7 6.7 0.0016 18.2 6.7 1.2 1 0 0 1 1 1 1 BAR domain Sec34 PF04136.15 PXF43353.1 - 0.0041 17.0 2.7 0.37 10.7 0.1 3.1 1 1 3 4 4 4 1 Sec34-like family DHR10 PF18595.1 PXF43353.1 - 0.0091 16.0 5.9 0.0091 16.0 5.9 1.8 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain AAA_13 PF13166.6 PXF43353.1 - 0.028 13.1 4.7 0.04 12.6 4.7 1.2 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 PXF43353.1 - 0.14 11.4 6.9 0.072 12.3 0.6 2.2 2 1 0 2 2 2 0 TMPIT-like protein Csm2_III-A PF03750.13 PXF43353.1 - 0.14 13.0 4.8 12 6.7 2.3 2.5 1 1 1 2 2 2 0 Csm2 Type III-A Baculo_PEP_C PF04513.12 PXF43353.1 - 0.2 11.7 5.1 0.46 10.5 1.5 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 PXF43353.1 - 0.22 11.6 10.9 2.1 8.4 8.9 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 PXF43353.1 - 0.31 10.8 7.1 0.55 10.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-K PF11802.8 PXF43353.1 - 0.4 10.2 6.4 0.18 11.3 3.5 1.7 1 1 0 1 1 1 0 Centromere-associated protein K EzrA PF06160.12 PXF43353.1 - 0.47 8.6 7.4 0.84 7.7 0.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 PXF43353.1 - 1 9.5 5.6 1.7 8.8 2.4 2.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FliD_C PF07195.12 PXF43353.1 - 2 7.8 9.9 5.7 6.3 1.6 2.3 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4164 PF13747.6 PXF43353.1 - 2 8.7 5.8 10 6.4 2.0 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) ZapB PF06005.12 PXF43353.1 - 2.1 8.8 6.8 4.4 7.8 3.0 2.8 3 0 0 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 PXF43353.1 - 2.4 8.2 6.9 1.5 8.9 0.3 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Taxilin PF09728.9 PXF43353.1 - 2.5 7.2 12.0 1.3 8.1 8.4 1.9 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF5082 PF16888.5 PXF43353.1 - 2.6 8.3 7.8 8 6.8 0.0 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF3713 PF12506.8 PXF43353.1 - 2.7 8.3 5.7 11 6.3 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) CENP-H PF05837.12 PXF43353.1 - 3.1 8.2 8.2 8.7 6.8 0.4 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Cluap1 PF10234.9 PXF43353.1 - 5.6 6.3 12.1 33 3.7 12.1 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 SRP14 PF02290.15 PXF43354.1 - 4.7e-18 65.4 0.0 5.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle 14kD protein tRNA_int_endo PF01974.17 PXF43356.1 - 2.1e-17 63.0 0.1 5e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SIMPL PF04402.14 PXF43356.1 - 0.077 13.4 4.1 0.18 12.2 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Nop25 PF09805.9 PXF43356.1 - 6.8 7.2 15.6 11 6.5 15.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SesA PF17107.5 PXF43357.1 - 0.00047 20.4 0.5 0.53 10.5 0.3 2.4 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 PXF43357.1 - 0.0026 17.7 0.2 0.41 10.5 0.2 2.4 1 1 1 2 2 2 1 Sec34-like family TMF_TATA_bd PF12325.8 PXF43357.1 - 0.0032 17.7 1.5 0.4 10.9 3.0 2.4 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding STAT_alpha PF01017.20 PXF43357.1 - 0.015 15.2 2.1 0.11 12.4 1.7 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Bap31_Bap29_C PF18035.1 PXF43357.1 - 0.045 13.8 0.5 2.3 8.3 0.0 3.0 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain BAR PF03114.18 PXF43357.1 - 0.047 13.3 4.7 0.16 11.5 4.7 1.9 1 1 0 1 1 1 0 BAR domain APG6_N PF17675.1 PXF43357.1 - 0.06 13.9 5.4 0.14 12.7 3.3 2.3 2 1 0 3 3 3 0 Apg6 coiled-coil region DUF713 PF05218.14 PXF43357.1 - 0.063 13.0 0.8 0.46 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF4337 PF14235.6 PXF43357.1 - 0.081 13.0 2.9 0.081 13.0 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) YabA PF06156.13 PXF43357.1 - 0.084 13.5 0.8 2.6 8.7 1.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 PXF43357.1 - 0.098 13.4 1.1 0.29 11.9 0.4 2.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 PXF43357.1 - 0.4 9.5 0.6 0.53 9.1 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SKA1 PF07160.12 PXF43359.1 - 1.1e-39 136.7 9.8 5.5e-39 134.4 9.8 1.8 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 PXF43359.1 - 0.069 13.6 0.9 9.3 6.8 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SesA PF17107.5 PXF43359.1 - 0.11 12.7 1.1 0.2 11.8 0.4 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SKA2 PF16740.5 PXF43359.1 - 0.19 11.5 5.1 0.14 11.9 2.1 2.3 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 SIP1 PF04938.12 PXF43359.1 - 0.38 10.4 5.7 0.7 9.6 4.8 2.0 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pneumo_att_G PF05539.11 PXF43359.1 - 1.3 8.6 10.2 1.7 8.2 10.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CCDC53 PF10152.9 PXF43359.1 - 2 8.8 7.6 3.5 8.0 7.6 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ApbA_C PF08546.11 PXF43360.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Ribosomal_L27A PF00828.19 PXF43361.1 - 5.5e-24 85.3 0.0 8.1e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RGI_lyase PF18370.1 PXF43364.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain Abhydrolase_3 PF07859.13 PXF43367.1 - 3.4e-46 157.8 0.0 6.2e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSL_N PF06350.12 PXF43367.1 - 4.5e-09 35.7 0.0 0.0003 19.9 0.0 2.3 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus Say1_Mug180 PF10340.9 PXF43367.1 - 6e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase zf-H2C2_2 PF13465.6 PXF43368.1 - 3.1e-07 30.5 0.8 3.1e-07 30.5 0.8 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 PXF43368.1 - 2.6e-06 27.5 12.4 0.00068 19.9 1.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 PXF43368.1 - 0.025 14.9 6.3 0.025 14.9 6.3 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 PXF43368.1 - 0.047 14.6 1.7 0.047 14.6 1.7 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF43368.1 - 0.1 12.9 0.6 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TcdB_toxin_midC PF12255.8 PXF43368.1 - 0.17 11.9 1.4 1.3 9.0 1.2 2.2 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/C-terminal region FOXP-CC PF16159.5 PXF43368.1 - 0.2 12.3 4.1 14 6.4 0.1 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain TFIIA PF03153.13 PXF43368.1 - 1.2 9.0 9.6 1.8 8.5 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amino_oxidase PF01593.24 PXF43369.1 - 6e-58 197.2 0.0 6.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF43369.1 - 2.7e-13 50.0 0.1 5.3e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 PXF43369.1 - 2.3e-06 26.7 0.0 0.049 12.4 0.0 2.2 2 0 0 2 2 2 2 MCRA family DAO PF01266.24 PXF43369.1 - 4.5e-06 26.5 4.6 0.00066 19.4 0.6 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PXF43369.1 - 9.2e-06 25.1 0.2 0.0013 18.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PXF43369.1 - 8.3e-05 22.0 0.2 0.00046 19.5 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF43369.1 - 0.00048 18.9 0.4 0.00048 18.9 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 PXF43369.1 - 0.0027 17.1 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF43369.1 - 0.012 14.8 1.5 0.036 13.2 0.8 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 PXF43369.1 - 0.012 14.7 0.3 0.021 13.9 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PXF43369.1 - 0.017 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PXF43369.1 - 0.018 15.0 0.2 0.037 13.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF43369.1 - 0.018 14.4 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PXF43369.1 - 0.053 14.1 0.3 0.26 11.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF43369.1 - 0.066 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF43369.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.12 PXF43369.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 PXF43369.1 - 0.17 12.4 0.1 0.42 11.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding zf-AN1 PF01428.16 PXF43370.1 - 4.6e-20 71.5 24.4 4.7e-11 42.7 6.6 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 PXF43370.1 - 0.033 14.6 10.8 0.075 13.4 1.4 2.6 2 0 0 2 2 2 0 C5HC2 zinc finger zf-C2HC5 PF06221.13 PXF43370.1 - 0.054 13.5 1.3 0.054 13.5 1.3 3.1 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Transp_Tc5_C PF04236.15 PXF43370.1 - 3.1 8.2 10.4 1 9.8 3.1 2.8 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Peptidase_M41 PF01434.18 PXF43371.1 - 4.8e-59 199.4 0.0 7.4e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PXF43371.1 - 1.5e-41 141.9 0.0 2.7e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF43371.1 - 3.4e-11 42.8 0.4 8.4e-11 41.5 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 PXF43371.1 - 9e-09 35.7 0.6 3.7e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 PXF43371.1 - 0.00081 19.4 0.0 0.003 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PXF43371.1 - 0.0032 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 PXF43371.1 - 0.0046 17.2 0.1 0.78 10.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PXF43371.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PXF43371.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF43371.1 - 0.025 14.9 0.3 0.4 11.1 0.1 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 PXF43371.1 - 0.042 14.0 0.0 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PXF43371.1 - 0.051 12.9 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_3 PF01171.20 PXF43372.1 - 1.8e-14 53.9 0.0 3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 PXF43372.1 - 3.2e-12 45.7 4.0 3.2e-12 45.7 4.0 3.3 4 0 0 4 4 4 1 Zinc-ribbon TF_Zn_Ribbon PF08271.12 PXF43372.1 - 0.12 11.9 4.1 0.14 11.7 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding GATA PF00320.27 PXF43372.1 - 0.65 9.7 6.0 11 5.7 0.2 3.1 3 0 0 3 3 3 0 GATA zinc finger SBBP PF06739.11 PXF43373.1 - 0.049 13.6 12.9 0.2 11.7 0.2 4.5 4 0 0 4 4 4 0 Beta-propeller repeat AAA PF00004.29 PXF43374.1 - 3.4e-14 53.4 0.0 1.2e-13 51.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 PXF43374.1 - 2e-13 50.3 0.1 1.1e-11 44.7 0.0 2.8 3 0 0 3 3 3 1 BAH domain AAA_22 PF13401.6 PXF43374.1 - 3.2e-10 40.4 0.0 8.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF43374.1 - 1.5e-09 38.5 0.0 2.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 PXF43374.1 - 6.2e-06 26.3 1.7 1e-05 25.5 0.1 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_30 PF13604.6 PXF43374.1 - 0.0059 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF43374.1 - 0.0095 16.3 0.3 0.029 14.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PXF43374.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 PXF43374.1 - 0.011 15.2 0.0 0.057 12.8 0.0 2.0 1 1 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 PXF43374.1 - 0.026 14.7 1.3 0.12 12.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 PXF43374.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PXF43374.1 - 0.099 12.4 0.0 0.099 12.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain DUF4724 PF15852.5 PXF43375.1 - 4.4 7.9 6.3 3 8.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4724) GLTP PF08718.11 PXF43376.1 - 2.2e-28 99.4 0.1 2.9e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Esterase PF00756.20 PXF43377.1 - 7.1e-47 160.2 0.0 8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 PXF43377.1 - 0.00063 19.1 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PXF43377.1 - 0.0028 17.5 0.4 0.18 11.6 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PXF43377.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 PXF43377.1 - 0.0087 15.6 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 PXF43377.1 - 0.028 15.0 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PXF43377.1 - 0.052 13.3 0.1 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 PXF43377.1 - 0.074 11.9 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 PXF43377.1 - 0.1 12.3 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hist_deacetyl PF00850.19 PXF43378.1 - 1.2e-50 172.7 0.0 1.8e-50 172.1 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain ABC_membrane PF00664.23 PXF43379.1 - 3.9e-81 272.7 27.4 2.5e-44 152.0 12.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF43379.1 - 1.3e-69 233.0 0.0 5.3e-35 120.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PXF43379.1 - 5.1e-13 49.0 3.1 5.7e-05 22.7 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF43379.1 - 3.8e-08 33.7 0.0 0.014 15.7 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PXF43379.1 - 4e-08 32.9 1.1 0.0075 16.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PXF43379.1 - 1.3e-07 32.1 0.2 0.013 15.9 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PXF43379.1 - 1e-06 28.7 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 PXF43379.1 - 7.2e-06 25.0 0.2 0.005 15.7 0.0 2.8 3 0 0 3 3 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 PXF43379.1 - 1.4e-05 25.0 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 PXF43379.1 - 0.00012 22.0 0.0 0.75 9.5 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 PXF43379.1 - 0.00023 20.9 0.1 0.66 9.7 0.0 3.2 4 0 0 4 4 3 2 AAA domain G-alpha PF00503.20 PXF43379.1 - 0.00029 20.1 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 PXF43379.1 - 0.00036 20.7 0.1 0.073 13.1 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_23 PF13476.6 PXF43379.1 - 0.00061 20.3 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 PXF43379.1 - 0.00094 19.6 0.0 2 8.9 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PXF43379.1 - 0.0029 18.1 0.0 0.92 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PXF43379.1 - 0.003 17.5 0.0 3 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PXF43379.1 - 0.0035 16.7 0.0 0.43 9.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 PXF43379.1 - 0.0045 16.9 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 PXF43379.1 - 0.0059 16.8 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PXF43379.1 - 0.009 15.5 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DBI_PRT PF02277.17 PXF43379.1 - 0.01 15.1 2.8 0.018 14.3 2.8 1.3 1 0 0 1 1 1 0 Phosphoribosyltransferase AAA_10 PF12846.7 PXF43379.1 - 0.016 14.1 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PRK PF00485.18 PXF43379.1 - 0.019 14.7 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 PXF43379.1 - 0.019 14.7 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PXF43379.1 - 0.02 14.4 0.0 3.6 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 PXF43379.1 - 0.024 14.4 0.0 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 PXF43379.1 - 0.033 14.6 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rop-like PF05082.13 PXF43379.1 - 0.04 13.7 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Rop-like Rad17 PF03215.15 PXF43379.1 - 0.071 13.0 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 PXF43379.1 - 0.092 12.8 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 PXF43379.1 - 0.13 11.9 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 PXF43379.1 - 0.2 10.8 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Peptidase_S24 PF00717.23 PXF43380.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Hydrolase_4 PF12146.8 PXF43381.1 - 1.4e-60 204.6 0.1 1.7e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF43381.1 - 6.3e-10 40.0 3.1 6.3e-10 40.0 3.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF43381.1 - 3.6e-09 36.6 0.1 5.1e-08 32.9 0.2 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PXF43381.1 - 4.5e-07 29.7 1.1 0.0032 17.1 0.3 3.1 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 PXF43381.1 - 0.00098 19.0 0.0 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase DLH PF01738.18 PXF43381.1 - 0.0012 18.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 PXF43381.1 - 0.0092 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 PXF43381.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Ribosomal_L7Ae PF01248.26 PXF43382.1 - 1.2e-29 101.9 0.8 1.5e-29 101.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PXF43382.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PTPS PF01242.19 PXF43383.1 - 6.2e-19 68.2 0.0 6.8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DDE_Tnp_4 PF13359.6 PXF43386.1 - 1.3e-18 67.2 0.0 2.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Abhydrolase_6 PF12697.7 PXF43387.1 - 3.3e-12 47.5 2.4 3.3e-12 47.5 2.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF43387.1 - 2.7e-07 30.5 0.0 3.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF43387.1 - 6.1e-06 25.7 0.0 8.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 PXF43387.1 - 0.00054 19.9 0.8 0.0088 15.9 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase zf-C2H2 PF00096.26 PXF43388.1 - 0.00023 21.4 7.7 0.00089 19.6 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF43388.1 - 0.00027 21.2 5.0 0.0022 18.4 1.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF43388.1 - 0.07 14.0 1.1 0.07 14.0 1.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CCHC_6 PF15288.6 PXF43389.1 - 0.0044 16.8 25.3 82 3.2 0.1 10.3 10 0 0 10 10 10 9 Zinc knuckle Peptidase_S8 PF00082.22 PXF43390.1 - 7.8e-14 51.6 1.6 3.1e-13 49.7 1.6 1.8 1 1 0 1 1 1 1 Subtilase family TraY PF05509.11 PXF43390.1 - 0.18 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 TraY domain CNOT1_HEAT PF16418.5 PXF43391.1 - 3.9e-05 23.8 0.2 5.7e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3584 PF12128.8 PXF43391.1 - 0.095 10.2 0.0 0.11 10.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CNOT1_CAF1_bind PF16415.5 PXF43392.1 - 1.7e-65 220.5 3.4 2.7e-65 219.9 3.4 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PXF43392.1 - 6.1e-34 117.1 0.4 6.1e-34 117.1 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 PXF43392.1 - 2e-33 115.2 0.0 3.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF4061 PF13270.6 PXF43393.1 - 0.016 15.5 2.2 0.016 15.5 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Cgr1 PF03879.14 PXF43393.1 - 1.4 9.3 16.9 0.35 11.3 4.4 2.2 2 0 0 2 2 2 0 Cgr1 family YIEGIA PF14045.6 PXF43395.1 - 0.033 13.1 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 YIEGIA protein PDDEXK_6 PF04720.12 PXF43395.1 - 1 9.2 5.0 1.6 8.7 0.5 2.0 1 1 1 2 2 2 0 PDDEXK-like family of unknown function ESSS PF10183.9 PXF43396.1 - 0.02 15.1 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PTPS PF01242.19 PXF43398.1 - 6.2e-19 68.2 0.0 6.8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Ribosomal_L7Ae PF01248.26 PXF43399.1 - 1.2e-29 101.9 0.8 1.5e-29 101.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PXF43399.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 L27_2 PF09045.10 PXF43400.1 - 0.043 13.8 2.4 0.076 13.0 2.4 1.6 1 1 0 1 1 1 0 L27_2 Hydrolase_4 PF12146.8 PXF43401.1 - 7e-11 41.8 0.0 8.2e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAS_7 PF12860.7 PXF43403.1 - 0.048 13.8 0.5 0.074 13.2 0.5 1.4 1 1 0 1 1 1 0 PAS fold DUF3421 PF11901.8 PXF43407.1 - 4.3e-37 126.6 0.9 2e-19 69.7 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF5610 PF18433.1 PXF43408.1 - 1.8 9.1 8.5 6.2 7.4 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5610) LTP_2 PF14368.6 PXF43409.1 - 5.5 7.2 8.7 0.29 11.3 0.7 2.7 2 1 0 3 3 3 0 Probable lipid transfer VWA PF00092.28 PXF43410.1 - 1.8e-16 60.9 0.2 2.6e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF43410.1 - 2.1e-07 31.6 0.1 4.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF43410.1 - 0.0022 18.0 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain RTT107_BRCT_5 PF16770.5 PXF43411.1 - 0.061 13.2 0.3 0.087 12.7 0.3 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DEAD PF00270.29 PXF43413.1 - 0.071 12.9 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase HA2 PF04408.23 PXF43414.1 - 1.6e-17 63.8 0.0 2.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) bZIP_2 PF07716.15 PXF43415.1 - 0.056 13.5 1.2 0.056 13.5 1.2 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Fer4_13 PF13370.6 PXF43416.1 - 3.2e-11 43.6 1.8 9.3e-11 42.1 1.8 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 PXF43416.1 - 1.6e-06 28.8 1.5 1.6e-06 28.8 1.5 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 PXF43416.1 - 0.023 14.8 5.4 0.026 14.7 0.0 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 PXF43416.1 - 0.042 14.0 6.0 1.5 9.0 6.2 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PXF43416.1 - 0.072 13.7 8.0 0.47 11.1 0.1 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain HEAT_2 PF13646.6 PXF43417.1 - 1.1e-19 70.6 8.7 1.2e-10 41.6 1.1 3.1 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 PXF43417.1 - 1.9e-09 37.0 6.7 0.015 15.5 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 PXF43417.1 - 6.8e-06 26.5 9.7 0.017 15.7 1.3 4.9 3 2 2 5 5 5 3 HEAT-like repeat HEAT_PBS PF03130.16 PXF43417.1 - 0.0014 19.1 18.0 0.058 14.1 0.2 6.0 5 1 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 PXF43417.1 - 0.034 14.4 0.0 17 5.7 0.0 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 SAP PF02037.27 PXF43418.1 - 1.4e-10 40.7 1.2 3.5e-10 39.4 1.2 1.7 1 0 0 1 1 1 1 SAP domain TPX2 PF06886.11 PXF43418.1 - 0.081 13.2 2.4 0.26 11.5 2.4 2.0 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) HeH PF12949.7 PXF43418.1 - 2 8.2 6.5 0.33 10.7 0.9 2.6 3 1 0 3 3 3 0 HeH/LEM domain YL1_C PF08265.11 PXF43419.1 - 2.4e-14 52.8 0.1 4.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GSHPx PF00255.19 PXF43420.1 - 2e-31 107.8 0.0 2.8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Lipoprotein_15 PF03640.15 PXF43420.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function Las1 PF04031.13 PXF43421.1 - 1.7e-30 106.1 1.0 2.3e-30 105.7 0.2 1.6 2 0 0 2 2 2 1 Las1-like Oxysterol_BP PF01237.18 PXF43422.1 - 2.3e-119 398.6 0.7 5.7e-119 397.3 0.0 1.9 2 1 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 PXF43422.1 - 2e-06 28.2 3.5 2.5e-06 27.9 0.5 2.7 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 PXF43422.1 - 1.9e-05 25.0 0.3 9.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 PXF43422.1 - 9.4e-05 22.6 0.0 0.00064 20.0 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 PXF43422.1 - 0.015 15.6 0.0 0.05 13.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Rad21_Rec8_N PF04825.13 PXF43423.1 - 3e-25 88.5 0.0 5.3e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PXF43423.1 - 7.4e-09 34.8 0.0 1.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein AMPK1_CBM PF16561.5 PXF43423.1 - 8.4e-07 29.1 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CNDH2_C PF16858.5 PXF43423.1 - 0.32 10.8 1.9 0.51 10.2 0.0 2.1 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Oxysterol_BP PF01237.18 PXF43424.1 - 3.1e-98 329.1 3.9 9.3e-97 324.2 3.9 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein FapA PF03961.13 PXF43425.1 - 0.0074 14.9 1.1 0.008 14.8 1.1 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Hc1 PF07432.13 PXF43425.1 - 0.012 16.0 2.8 0.012 16.0 2.8 1.4 1 1 0 1 1 1 0 Histone H1-like protein Hc1 Sec2p PF06428.11 PXF43425.1 - 0.076 13.0 9.9 0.21 11.5 1.9 2.0 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p STAT_alpha PF01017.20 PXF43425.1 - 0.079 12.9 3.4 0.088 12.7 3.4 1.0 1 0 0 1 1 1 0 STAT protein, all-alpha domain H-kinase_dim PF02895.14 PXF43425.1 - 0.093 13.1 2.1 0.17 12.3 2.2 1.5 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain MRP-L46 PF11788.8 PXF43426.1 - 8.8e-07 29.7 0.2 0.00023 21.9 0.0 2.5 1 1 1 2 2 2 2 39S mitochondrial ribosomal protein L46 RmlD_sub_bind PF04321.17 PXF43427.1 - 4.5e-24 85.0 0.0 6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 PXF43427.1 - 6.9e-09 35.5 0.0 9.1e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF43427.1 - 0.004 16.6 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Bestrophin PF01062.21 PXF43428.1 - 8.7e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Hydrolase_4 PF12146.8 PXF43429.1 - 3.1e-33 115.0 0.0 3.6e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF43429.1 - 5e-11 43.6 0.0 6.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF43429.1 - 2.1e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PXF43429.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PXF43429.1 - 0.028 13.9 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 PXF43429.1 - 0.23 11.1 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF1995 PF09353.10 PXF43430.1 - 2e-10 41.0 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Pro_isomerase PF00160.21 PXF43432.1 - 3.8e-16 59.7 0.0 8.5e-16 58.6 0.0 1.5 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PLRV_ORF5 PF01690.17 PXF43432.1 - 0.26 9.9 1.6 0.49 9.1 1.6 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Bestrophin PF01062.21 PXF43435.1 - 5.2e-27 95.0 0.0 6.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ABC_membrane PF00664.23 PXF43436.1 - 4e-60 203.8 33.1 8.1e-33 114.2 9.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF43436.1 - 8.8e-53 178.5 0.0 2.6e-31 109.0 0.0 3.0 2 0 0 2 2 2 2 ABC transporter DUF87 PF01935.17 PXF43436.1 - 1.4e-06 28.6 1.4 0.006 16.7 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain SMC_N PF02463.19 PXF43436.1 - 2.6e-06 27.0 2.7 1.8 8.0 1.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF43436.1 - 3.6e-06 27.3 0.9 0.14 12.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 PXF43436.1 - 1.5e-05 25.0 2.3 0.17 11.9 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PXF43436.1 - 1.9e-05 24.3 0.5 0.024 14.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PXF43436.1 - 2.7e-05 24.6 0.3 0.43 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PXF43436.1 - 8.1e-05 22.6 0.5 0.067 13.1 0.0 2.9 3 1 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 PXF43436.1 - 0.0001 22.9 0.1 0.17 12.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PXF43436.1 - 0.0005 19.8 0.0 0.51 10.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 PXF43436.1 - 0.0012 18.3 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 PXF43436.1 - 0.0016 18.0 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 PXF43436.1 - 0.003 17.4 7.4 0.18 11.6 0.1 4.0 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 PXF43436.1 - 0.0055 16.5 0.1 0.39 10.4 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 PXF43436.1 - 0.0063 16.1 0.1 0.034 13.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF43436.1 - 0.015 15.1 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PXF43436.1 - 0.018 15.2 0.5 0.23 11.6 0.1 2.7 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 PXF43436.1 - 0.018 14.8 0.4 3.4 7.4 0.1 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 PXF43436.1 - 0.02 15.0 1.3 0.98 9.5 0.1 2.7 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 PXF43436.1 - 0.041 12.9 0.2 0.13 11.3 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 PXF43436.1 - 0.056 12.3 0.4 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 PXF43436.1 - 0.099 12.5 1.7 1.1 9.1 0.4 2.8 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 PXF43436.1 - 0.1 12.4 0.2 10 5.8 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 PXF43436.1 - 0.11 12.9 0.3 54 4.2 0.1 3.4 3 0 0 3 3 3 0 RNA helicase AAA_10 PF12846.7 PXF43436.1 - 0.16 10.9 0.3 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ECH_1 PF00378.20 PXF43437.1 - 5e-33 114.4 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PXF43437.1 - 1.7e-11 44.2 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PRKCSH PF07915.13 PXF43438.1 - 1.1e-14 55.2 4.8 1.4e-13 51.6 0.3 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PXF43438.1 - 1.2e-05 25.1 0.8 0.0006 19.5 0.8 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein CLP_protease PF00574.23 PXF43439.1 - 3.6e-53 180.2 0.1 6.4e-53 179.3 0.1 1.3 1 1 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 PXF43439.1 - 0.015 15.2 0.6 0.086 12.8 0.0 2.2 3 0 0 3 3 3 0 Peptidase family S49 PD40 PF07676.12 PXF43440.1 - 0.007 16.3 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 PXF43440.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain UQ_con PF00179.26 PXF43441.1 - 4.1e-37 126.9 0.0 5.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PI3_PI4_kinase PF00454.27 PXF43442.1 - 3.5e-44 151.5 0.0 6.9e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PXF43442.1 - 2.7e-23 82.8 0.2 5.2e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 PXF43442.1 - 9.9e-09 34.9 1.2 9.9e-09 34.9 1.2 2.1 2 0 0 2 2 2 1 FATC domain UME PF08064.13 PXF43442.1 - 3.3e-08 33.4 2.5 1e-07 31.8 0.1 3.4 3 0 0 3 3 3 1 UME (NUC010) domain DUF3385 PF11865.8 PXF43442.1 - 0.018 15.0 0.4 0.2 11.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) TPR_11 PF13414.6 PXF43442.1 - 0.055 13.2 0.9 0.57 9.9 0.2 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 PXF43442.1 - 2.6 9.1 5.7 3.9 8.5 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF43442.1 - 3.1 8.1 5.1 0.87 9.9 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GATA PF00320.27 PXF43443.1 - 2e-18 65.7 5.4 3.2e-18 65.0 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger FAM76 PF16046.5 PXF43443.1 - 0.031 13.6 0.4 0.04 13.3 0.4 1.1 1 0 0 1 1 1 0 FAM76 protein Metallophos PF00149.28 PXF43444.1 - 9.6e-14 52.4 0.3 1.3e-13 51.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APG6_N PF17675.1 PXF43445.1 - 2.3 8.7 9.6 1.6 9.3 3.0 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Carb_anhydrase PF00194.21 PXF43446.1 - 8.5e-31 107.4 0.5 1.9e-30 106.2 0.5 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 PXF43446.1 - 0.059 13.3 0.2 0.059 13.3 0.2 1.7 2 0 0 2 2 2 0 Putative carbonic anhydrase IPK PF03770.16 PXF43447.1 - 6.3e-36 124.1 0.0 9.4e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pkinase PF00069.25 PXF43448.1 - 1.2e-78 264.1 0.0 1.5e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43448.1 - 1.9e-42 145.4 0.0 2.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43448.1 - 1.1e-11 44.7 0.0 3.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PXF43448.1 - 5.8e-05 22.0 0.0 8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PXF43448.1 - 0.00013 21.7 0.5 0.00031 20.4 0.5 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PXF43448.1 - 0.00023 21.1 0.0 0.54 10.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF43448.1 - 0.00025 20.4 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_17 PF18012.1 PXF43448.1 - 0.042 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 PH domain Ribosomal_S14 PF00253.21 PXF43449.1 - 1.4e-12 47.2 5.7 1.5e-12 47.1 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ank_2 PF12796.7 PXF43450.1 - 8.4e-10 39.1 0.0 1.3e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF43450.1 - 1.7e-09 37.8 0.1 1.8e-07 31.3 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF43450.1 - 2e-07 30.7 0.1 0.0061 17.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PXF43450.1 - 6.9e-07 29.4 0.1 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PXF43450.1 - 6e-05 23.5 0.0 2.5 8.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 PXF43451.1 - 2.8e-14 53.6 0.0 6.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PXF43451.1 - 1.5e-12 48.1 0.0 4.5e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF43451.1 - 2.1e-08 34.8 0.7 3.4e-07 30.8 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 PXF43451.1 - 2.2e-06 27.6 0.0 6.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 PXF43451.1 - 8.7e-06 26.1 0.0 2.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PXF43451.1 - 0.00032 20.3 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 PXF43451.1 - 0.0017 18.3 0.9 0.17 11.8 0.3 3.2 3 1 0 3 3 2 1 NACHT domain AAA_lid_10 PF17872.1 PXF43451.1 - 0.004 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_11 PF13086.6 PXF43451.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF43451.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PXF43451.1 - 0.015 15.5 0.1 0.076 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 PXF43451.1 - 0.015 14.5 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 PXF43451.1 - 0.032 14.2 0.8 0.079 12.9 0.2 2.0 2 1 0 2 2 2 0 NTPase AAA_18 PF13238.6 PXF43451.1 - 0.04 14.4 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 PXF43451.1 - 0.086 11.8 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 PXF43451.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 PXF43451.1 - 0.11 12.5 0.0 8.7 6.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PXF43451.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_32 PF13654.6 PXF43451.1 - 0.26 10.0 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PXF43452.1 - 1.4e-68 231.3 0.6 4.3e-63 213.3 0.2 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 PXF43452.1 - 4.2e-07 29.7 0.3 0.00033 20.2 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF43452.1 - 1.6e-05 24.8 0.0 0.17 11.8 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 PXF43452.1 - 2.1e-05 24.2 0.1 4.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PXF43452.1 - 0.00014 22.3 0.0 0.00048 20.5 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 PXF43452.1 - 0.00018 21.1 0.0 0.004 16.7 0.0 2.6 2 1 1 3 3 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 PXF43452.1 - 0.00023 21.2 0.0 0.007 16.4 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 PXF43452.1 - 0.0009 18.3 1.2 0.053 12.5 0.2 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 PXF43452.1 - 0.0011 18.4 0.1 1 8.7 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 PXF43452.1 - 0.0012 19.0 0.3 0.0042 17.2 0.0 2.2 2 2 0 2 2 1 1 AAA domain AAA_23 PF13476.6 PXF43452.1 - 0.0025 18.3 0.1 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 PXF43452.1 - 0.0056 16.2 0.1 3.4 7.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.19 PXF43452.1 - 0.011 15.3 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 PXF43452.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PXF43452.1 - 0.041 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PXF43452.1 - 0.048 14.2 0.0 0.23 12.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Thioredoxin_6 PF13848.6 PXF43452.1 - 0.059 13.3 0.1 0.51 10.2 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin-like domain NACHT PF05729.12 PXF43452.1 - 0.066 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain dNK PF01712.19 PXF43452.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase SRP54 PF00448.22 PXF43452.1 - 0.074 12.7 0.5 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 PXF43452.1 - 0.092 12.8 2.1 0.3 11.2 0.1 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 PXF43452.1 - 0.12 12.1 0.1 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 PXF43452.1 - 0.12 12.0 0.4 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PXF43452.1 - 0.16 11.7 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TPR_12 PF13424.6 PXF43453.1 - 4.8e-09 36.4 3.6 1.7e-07 31.4 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AMPK1_CBM PF16561.5 PXF43453.1 - 1.3e-08 34.9 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TPR_2 PF07719.17 PXF43453.1 - 2.1e-05 24.3 2.2 0.037 14.1 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF43453.1 - 0.00014 21.6 4.8 0.00087 19.1 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF43453.1 - 0.0013 19.3 0.0 0.43 11.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF43453.1 - 0.014 15.2 0.4 1.3 8.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 PXF43453.1 - 0.016 14.6 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 PXF43453.1 - 0.85 10.2 4.2 1.3 9.5 0.1 2.6 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF4649 PF15507.6 PXF43454.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) DUF905 PF06006.12 PXF43454.1 - 0.19 11.7 0.5 0.22 11.6 0.4 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF905) DUF4580 PF15162.6 PXF43455.1 - 0.043 13.4 0.0 2.6e+02 1.1 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4580) DUF3248 PF11609.8 PXF43455.1 - 0.052 13.5 4.8 44 4.1 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3248) DUF3349 PF11829.8 PXF43455.1 - 0.24 12.2 2.2 2.2e+02 2.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3349) YokU PF14122.6 PXF43456.1 - 0.1 12.6 0.3 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin PNP_UDP_1 PF01048.20 PXF43457.1 - 4.6e-21 75.2 0.1 5.8e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily IFR3_antag PF14754.6 PXF43457.1 - 0.0065 15.7 0.2 0.36 10.0 0.1 2.2 2 0 0 2 2 2 2 Papain-like auto-proteinase Creatininase PF02633.14 PXF43458.1 - 0.063 12.7 1.2 0.064 12.7 1.2 1.0 1 0 0 1 1 1 0 Creatinine amidohydrolase Dsh_C PF12316.8 PXF43458.1 - 0.17 12.2 2.2 0.2 12.0 2.2 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 PXF43458.1 - 0.42 9.3 4.6 0.39 9.4 4.6 1.0 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 PXF43458.1 - 0.68 8.8 9.0 0.75 8.6 9.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.16 PXF43458.1 - 0.72 9.2 10.2 0.86 8.9 10.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Borrelia_P83 PF05262.11 PXF43458.1 - 2.6 6.5 8.6 2.9 6.3 8.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 PXF43458.1 - 9.4 6.0 10.0 12 5.6 10.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP33 PF01430.19 PXF43460.1 - 1.9e-64 217.6 0.0 2.3e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein TF_Zn_Ribbon PF08271.12 PXF43460.1 - 0.1 12.1 0.7 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding COPIIcoated_ERV PF07970.12 PXF43461.1 - 6.6e-65 219.0 0.0 8.7e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PXF43461.1 - 5.1e-22 78.0 0.1 5.1e-22 78.0 0.1 2.0 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SKG6 PF08693.10 PXF43461.1 - 0.39 10.2 5.6 0.95 8.9 5.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NCBP3 PF10309.9 PXF43462.1 - 1.1e-14 54.0 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 PXF43462.1 - 0.0043 17.0 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain PEN-2 PF10251.9 PXF43463.1 - 4.2e-11 43.1 2.9 6.4e-11 42.5 2.9 1.3 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase RII_binding_1 PF10522.9 PXF43463.1 - 0.3 11.4 2.3 19 5.9 0.0 2.8 3 0 0 3 3 3 0 RII binding domain BACK PF07707.15 PXF43464.1 - 8.7e-05 22.6 0.2 0.0019 18.2 0.2 2.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch TMPIT PF07851.13 PXF43465.1 - 4.5e-80 269.3 7.7 6.2e-80 268.9 7.7 1.2 1 0 0 1 1 1 1 TMPIT-like protein Mod_r PF07200.13 PXF43465.1 - 0.086 12.9 5.7 0.036 14.2 2.4 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1635 PF07795.11 PXF43465.1 - 0.1 12.5 6.8 0.15 11.9 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FAM76 PF16046.5 PXF43465.1 - 0.41 10.0 3.7 0.58 9.5 3.7 1.3 1 0 0 1 1 1 0 FAM76 protein SKA1 PF07160.12 PXF43465.1 - 0.49 10.2 4.2 0.76 9.6 4.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Uds1 PF15456.6 PXF43465.1 - 0.72 10.0 10.1 0.76 9.9 7.7 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Ribosomal_L24e PF01246.20 PXF43467.1 - 7.9e-31 106.1 2.6 1.5e-30 105.2 2.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5086 PF16985.5 PXF43467.1 - 0.0068 16.3 0.3 0.028 14.3 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF5086) DUF2175 PF09943.9 PXF43467.1 - 1.3 9.4 4.3 2.7 8.3 0.2 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) COG7 PF10191.9 PXF43468.1 - 4.3e-62 210.5 1.2 2.7e-33 115.2 0.0 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) RB_A PF01858.17 PXF43468.1 - 0.0095 15.8 0.2 0.98 9.2 0.0 2.4 2 0 0 2 2 2 1 Retinoblastoma-associated protein A domain ATP-synt_D PF01813.17 PXF43468.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit D RINT1_TIP1 PF04437.13 PXF43468.1 - 0.12 11.2 1.0 6.8 5.5 0.0 3.3 4 0 0 4 4 4 0 RINT-1 / TIP-1 family COG5 PF10392.9 PXF43468.1 - 0.13 12.5 3.2 0.063 13.5 0.4 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 adh_short PF00106.25 PXF43469.1 - 9.6e-23 80.7 0.1 1.7e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF43469.1 - 7e-18 65.0 0.3 1.3e-16 60.9 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF43469.1 - 1.4e-05 25.1 0.4 5.2e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 KR domain DUF5490 PF17593.2 PXF43469.1 - 0.056 13.5 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5490) PAP_central PF04928.17 PXF43472.1 - 4.2e-50 170.0 0.0 6.9e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PXF43472.1 - 3.8e-12 46.2 0.3 7.4e-12 45.2 0.3 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PXF43472.1 - 2.3e-06 27.8 0.0 5.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PXF43472.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase WXG100 PF06013.12 PXF43475.1 - 0.0023 18.1 0.1 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF43475.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) AAA PF00004.29 PXF43477.1 - 8.7e-18 65.0 0.0 1.7e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF43477.1 - 0.00041 20.8 0.0 0.00084 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 PXF43477.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF43477.1 - 0.088 13.1 0.1 0.47 10.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 PXF43477.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PXF43477.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 PXF43477.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ILVD_EDD PF00920.21 PXF43478.1 - 1.6e-195 650.7 5.5 1.8e-195 650.5 5.5 1.0 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.25 PXF43479.1 - 2.8e-68 230.1 0.0 4.7e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43479.1 - 4.9e-40 137.4 0.0 7.7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43479.1 - 6.9e-05 22.3 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like TFIIIC_sub6 PF10419.9 PXF43480.1 - 0.00013 21.8 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain TMF_TATA_bd PF12325.8 PXF43481.1 - 4.1e-25 88.2 6.7 4.1e-25 88.2 6.7 7.1 2 1 4 6 6 6 1 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 PXF43481.1 - 0.00062 18.8 6.8 0.00062 18.8 6.8 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF812) Rootletin PF15035.6 PXF43481.1 - 0.016 15.3 1.2 0.016 15.3 1.2 5.5 2 1 3 5 5 5 0 Ciliary rootlet component, centrosome cohesion HIP1_clath_bdg PF16515.5 PXF43481.1 - 0.059 14.0 0.8 0.059 14.0 0.8 7.9 3 1 6 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med1 PF10744.9 PXF43482.1 - 1.4e-06 27.7 2.6 3.8e-06 26.2 0.2 2.1 1 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Tfb5 PF06331.12 PXF43483.1 - 1.3e-25 89.2 0.2 1.6e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 zinc_ribbon_6 PF14599.6 PXF43484.1 - 1.1e-20 73.3 3.6 1.1e-20 73.3 3.6 4.6 4 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 PXF43484.1 - 6.3e-18 65.0 24.7 6.3e-18 65.0 24.7 4.7 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 PXF43484.1 - 1.5e-08 34.8 5.6 1.5e-08 34.8 5.6 5.8 3 1 3 6 6 6 1 Ring finger domain zf-RING_5 PF14634.6 PXF43484.1 - 1.1e-05 25.3 8.0 1.1e-05 25.3 8.0 6.6 3 1 2 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PXF43484.1 - 8.3e-05 22.3 7.5 8.3e-05 22.3 7.5 5.9 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF43484.1 - 0.00036 20.8 8.5 0.00036 20.8 8.5 5.6 3 1 2 5 5 5 1 RING-H2 zinc finger domain zf-LSD1 PF06943.12 PXF43484.1 - 0.42 10.5 0.1 0.42 10.5 0.1 6.5 10 0 0 10 10 10 0 LSD1 zinc finger PPR_2 PF13041.6 PXF43485.1 - 9.6e-30 102.5 2.2 1.2e-07 31.8 0.0 8.7 8 1 2 10 10 10 7 PPR repeat family PPR_3 PF13812.6 PXF43485.1 - 5.2e-23 80.9 0.4 1.5e-05 24.9 0.0 7.1 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 PXF43485.1 - 2.5e-22 77.5 8.8 0.00079 19.5 0.0 11.4 13 0 0 13 13 11 4 PPR repeat PPR_1 PF12854.7 PXF43485.1 - 7.7e-16 57.5 0.4 0.00019 21.1 0.0 7.4 7 1 1 8 8 8 3 PPR repeat PPR_long PF17177.4 PXF43485.1 - 9e-09 35.0 8.2 9.7e-05 21.8 0.1 5.8 3 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP Mic1 PF07035.12 PXF43485.1 - 0.0024 17.6 2.5 0.0026 17.5 0.5 2.1 3 0 0 3 3 3 1 Colon cancer-associated protein Mic1-like AEP1 PF17049.5 PXF43485.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 ATPase expression protein 1 TPR_19 PF14559.6 PXF43485.1 - 0.021 15.3 4.8 2.6 8.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP13 PF12921.7 PXF43485.1 - 0.043 13.7 1.3 1.7 8.6 0.0 3.2 3 1 0 4 4 4 0 Mitochondrial ATPase expression TEX12 PF15219.6 PXF43485.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed 12 PRIMA1 PF16101.5 PXF43485.1 - 7.1 6.7 9.2 18 5.4 9.2 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SBF PF01758.16 PXF43486.1 - 5.4e-21 75.2 21.3 3.5e-20 72.5 16.4 2.4 3 0 0 3 3 3 2 Sodium Bile acid symporter family SBF_like PF13593.6 PXF43486.1 - 1.8e-10 40.7 18.8 2.4e-10 40.3 18.8 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Thioredoxin_13 PF18401.1 PXF43487.1 - 0.019 14.9 0.2 0.054 13.4 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain PPR_2 PF13041.6 PXF43488.1 - 2.8e-07 30.6 0.2 0.021 15.0 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 PXF43488.1 - 6.9e-05 22.8 1.0 0.16 12.3 0.1 2.8 3 0 0 3 3 3 2 PPR repeat TEX12 PF15219.6 PXF43488.1 - 0.0098 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 Testis-expressed 12 PPR_3 PF13812.6 PXF43488.1 - 0.014 15.5 0.1 0.083 13.0 0.1 2.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PMR5N PF14416.6 PXF43489.1 - 0.08 13.3 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 PMR5 N terminal Domain Nudix_N PF12535.8 PXF43490.1 - 0.046 13.3 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal zinc_ribbon_6 PF14599.6 PXF43491.1 - 1.2e-19 70.0 3.5 1.9e-19 69.4 3.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon QWRF PF04484.12 PXF43492.1 - 1.9e-05 24.6 5.2 1.9e-05 24.6 5.2 1.8 2 0 0 2 2 2 1 QWRF family Filament PF00038.21 PXF43493.1 - 0.00017 21.3 37.6 0.00017 21.3 37.6 15.1 1 1 11 14 14 14 5 Intermediate filament protein APG6_N PF17675.1 PXF43493.1 - 0.0047 17.5 20.1 0.0047 17.5 20.1 19.8 3 3 16 19 19 19 5 Apg6 coiled-coil region CVNH PF08881.10 PXF43493.1 - 0.6 10.8 16.3 10 6.9 0.0 7.2 5 3 0 5 5 5 0 CVNH domain Thioredoxin PF00085.20 PXF43494.1 - 2.3e-26 91.7 0.1 8.4e-26 90.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin TPR_2 PF07719.17 PXF43494.1 - 7.5e-06 25.7 4.7 0.011 15.7 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF43494.1 - 7.2e-05 22.9 1.5 0.068 13.3 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF43494.1 - 0.0015 18.3 4.2 0.036 13.9 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat HipN PF18253.1 PXF43494.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_11 PF13414.6 PXF43494.1 - 0.027 14.2 1.4 4.3 7.1 0.1 2.7 2 0 0 2 2 2 0 TPR repeat Ribosomal_60s PF00428.19 PXF43494.1 - 0.028 15.0 0.2 0.028 15.0 0.2 4.8 4 2 0 4 4 1 0 60s Acidic ribosomal protein Thioredoxin_8 PF13905.6 PXF43494.1 - 0.032 14.5 0.0 0.58 10.5 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 PXF43494.1 - 0.046 14.2 1.9 0.27 11.7 0.1 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain OST3_OST6 PF04756.13 PXF43494.1 - 0.052 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 PXF43494.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Redoxin TPR_12 PF13424.6 PXF43494.1 - 4.1 7.8 9.1 0.35 11.2 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ERG2_Sigma1R PF04622.12 PXF43495.1 - 1.2e-76 256.7 0.1 1.5e-76 256.4 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GDH_N PF12466.8 PXF43495.1 - 0.14 12.3 0.2 3.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal LRR_8 PF13855.6 PXF43496.1 - 2.7e-19 68.7 20.2 5.6e-10 38.8 3.7 3.8 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PXF43496.1 - 2e-17 63.0 14.8 0.0006 20.1 0.0 5.2 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PXF43496.1 - 2e-06 27.6 13.6 1.4 9.8 0.4 7.2 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 PXF43496.1 - 0.00019 21.2 14.0 5.5 7.3 0.2 6.2 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 PXF43496.1 - 0.54 9.7 3.5 0.64 9.5 0.7 2.2 1 1 0 2 2 2 0 Leucine-rich repeat Glyco_transf_7C PF02709.14 PXF43497.1 - 3.9e-07 29.6 0.0 7.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 PXF43497.1 - 0.00031 20.6 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF43497.1 - 0.0097 15.8 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF43497.1 - 0.018 14.5 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 HEV_ORF1 PF02444.16 PXF43497.1 - 0.037 14.6 0.2 0.14 12.7 0.2 2.0 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Wbp11 PF09429.10 PXF43498.1 - 0.19 12.2 2.0 0.4 11.1 1.1 2.1 1 1 1 2 2 2 0 WW domain binding protein 11 ORF6C PF10552.9 PXF43498.1 - 0.4 10.8 6.8 1.1 9.4 0.4 3.1 2 1 1 3 3 3 0 ORF6C domain DUF4337 PF14235.6 PXF43498.1 - 0.72 10.0 2.3 1.5 8.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1664 PF07889.12 PXF43498.1 - 3 7.9 4.5 7.4 6.6 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NDUFB10 PF10249.9 PXF43499.1 - 0.00075 20.0 0.1 0.0009 19.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Carb_kinase PF01256.17 PXF43500.1 - 3.9e-46 157.5 0.1 4.8e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Peptidase_U57 PF05582.12 PXF43500.1 - 0.07 12.4 0.0 5.6 6.1 0.0 2.1 2 0 0 2 2 2 0 YabG peptidase U57 HMw1_D2 PF18254.1 PXF43501.1 - 0.069 13.5 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 HMW1 domain 2 Glyco_transf_92 PF01697.27 PXF43502.1 - 4.8e-09 36.2 2.2 7.8e-09 35.6 2.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PXF43502.1 - 1.6e-08 34.9 0.5 4.6e-08 33.5 0.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF1897 PF09005.10 PXF43502.1 - 0.14 11.7 1.5 0.24 10.9 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Prenyltrans PF00432.21 PXF43503.1 - 1.1e-54 181.8 16.8 5.7e-13 48.4 0.5 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 PXF43503.1 - 5.6e-06 25.7 0.0 0.31 10.1 0.0 3.1 1 1 2 3 3 3 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 PXF43503.1 - 0.0013 17.9 0.0 0.015 14.4 0.0 2.2 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain Trypsin_2 PF13365.6 PXF43504.1 - 5.3e-32 111.8 0.1 9e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF43504.1 - 7.9e-14 52.0 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PXF43504.1 - 6.7e-12 45.6 0.7 1.2e-11 44.8 0.2 1.7 2 0 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 PXF43504.1 - 0.0036 17.1 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease GRASP55_65 PF04495.14 PXF43504.1 - 0.012 15.9 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_S32 PF05579.13 PXF43504.1 - 0.045 12.9 0.3 7 5.7 0.1 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 PXF43504.1 - 0.059 12.0 0.3 0.14 10.8 0.3 1.5 2 0 0 2 2 2 0 Peptidase S46 PDZ_6 PF17820.1 PXF43504.1 - 0.17 11.7 1.2 2.7 7.9 0.1 3.0 3 0 0 3 3 3 0 PDZ domain R3H PF01424.22 PXF43505.1 - 4.5e-08 32.9 1.5 9.5e-08 31.9 1.5 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 PXF43505.1 - 0.00036 21.2 1.0 0.00036 21.2 1.0 4.2 3 1 0 3 3 3 1 SUZ domain TIMP PF00965.17 PXF43506.1 - 0.05 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase HTH_26 PF13443.6 PXF43507.1 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Top6b_C PF18000.1 PXF43508.1 - 0.076 13.2 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain HTH_Tnp_Tc5 PF03221.16 PXF43510.1 - 0.00073 19.5 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 PXF43510.1 - 0.019 14.7 0.8 0.031 14.1 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 PXF43510.1 - 0.022 14.4 0.2 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 PXF43510.1 - 0.034 13.9 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Skp1 PF01466.19 PXF43511.1 - 0.00011 22.2 0.0 0.00035 20.6 0.0 1.9 1 0 0 1 1 1 1 Skp1 family, dimerisation domain TolA_bind_tri PF16331.5 PXF43511.1 - 2.1 8.5 7.6 5.3 7.2 7.6 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation zf-MYND PF01753.18 PXF43512.1 - 1.2e-09 38.1 10.7 2e-09 37.4 10.7 1.4 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 PXF43512.1 - 1.7e-09 37.7 0.0 0.0015 18.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PXF43512.1 - 7.4e-08 32.5 0.0 0.00034 20.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PXF43512.1 - 5.5e-05 23.7 0.0 0.0037 17.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF43512.1 - 0.00059 20.3 0.1 1.8 9.3 0.0 4.0 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF43512.1 - 0.0014 18.9 0.1 5.1 8.0 0.0 3.8 3 2 0 3 3 3 2 Ankyrin repeat PolC_DP2 PF03833.13 PXF43512.1 - 0.051 11.4 2.3 0.074 10.9 2.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 YebO PF13974.6 PXF43513.1 - 0.046 13.8 0.8 0.062 13.4 0.4 1.5 1 1 0 1 1 1 0 YebO-like protein DUF4291 PF14124.6 PXF43514.1 - 1.1e-55 188.3 0.0 1.4e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Glyco_hydro_31 PF01055.26 PXF43515.1 - 3.7e-74 250.5 1.5 5.5e-74 249.9 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 PXF43515.1 - 0.015 15.5 0.2 0.063 13.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 PXF43517.1 - 7.4e-71 239.6 5.9 7.4e-71 239.6 5.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 PhoLip_ATPase_C PF16212.5 PXF43518.1 - 3e-73 246.6 13.9 3e-73 246.6 13.9 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PXF43518.1 - 3.2e-18 65.2 1.2 7.1e-18 64.1 1.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PXF43518.1 - 1.5e-11 44.3 0.0 8.1e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF43518.1 - 2.3e-11 44.4 4.5 2.3e-06 28.1 1.0 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PXF43518.1 - 4.4e-06 26.3 0.0 2.5e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PXF43518.1 - 0.0011 18.8 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PXF43518.1 - 0.11 12.6 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase OFeT_1 PF16955.5 PXF43518.1 - 0.16 11.7 2.1 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Mito_carr PF00153.27 PXF43519.1 - 6.2e-33 112.6 7.0 8.2e-20 70.5 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.22 PXF43520.1 - 1.1e-216 720.8 0.0 1.8e-216 720.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PXF43520.1 - 2.9e-24 85.8 0.0 1.5e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PXF43520.1 - 4.3e-12 45.5 1.1 0.00079 18.3 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PXF43520.1 - 0.0058 16.0 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ABC_tran PF00005.27 PXF43521.1 - 8.8e-42 142.9 0.0 1.1e-21 77.7 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PXF43521.1 - 1.4e-15 57.9 0.0 2e-06 27.9 0.0 4.8 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF43521.1 - 1.9e-14 53.6 0.2 0.00041 19.9 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PXF43521.1 - 6.7e-07 30.0 2.6 0.035 14.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PXF43521.1 - 3.4e-05 23.5 0.0 0.069 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 PXF43521.1 - 8.5e-05 23.0 0.0 0.25 11.8 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PXF43521.1 - 0.00019 21.3 1.0 0.74 9.5 0.1 4.0 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 PXF43521.1 - 0.00022 21.5 0.0 0.36 11.1 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 PXF43521.1 - 0.0003 21.1 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 PXF43521.1 - 0.00093 19.3 0.1 0.7 10.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 PXF43521.1 - 0.0029 17.8 0.0 0.11 12.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 PXF43521.1 - 0.0029 18.0 0.3 0.26 11.6 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 PXF43521.1 - 0.0031 18.1 0.0 0.48 11.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_27 PF13514.6 PXF43521.1 - 0.0035 17.0 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IFRD PF05004.13 PXF43521.1 - 0.0048 16.1 3.0 0.01 15.0 0.6 2.5 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) RNA_helicase PF00910.22 PXF43521.1 - 0.006 17.0 0.0 4.1 7.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 PXF43521.1 - 0.0064 16.5 0.0 0.87 9.6 0.0 3.2 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 PXF43521.1 - 0.016 14.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 PXF43521.1 - 0.018 14.8 0.0 3.2 7.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3385 PF11865.8 PXF43521.1 - 0.027 14.4 0.9 2 8.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) RsgA_GTPase PF03193.16 PXF43521.1 - 0.032 14.2 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CLASP_N PF12348.8 PXF43521.1 - 0.032 13.8 6.1 1.1 8.7 0.2 2.5 2 0 0 2 2 2 0 CLASP N terminal 4HB PF17947.1 PXF43521.1 - 0.033 14.2 0.0 0.17 12.0 0.0 2.3 1 0 0 1 1 1 0 Four helical bundle domain AAA_24 PF13479.6 PXF43521.1 - 0.036 13.8 0.0 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Chromo PF00385.24 PXF43521.1 - 0.067 13.1 0.1 0.067 13.1 0.1 1.8 2 0 0 2 2 1 0 Chromo (CHRromatin Organisation MOdifier) domain Adaptin_N PF01602.20 PXF43521.1 - 0.095 11.2 5.6 0.033 12.8 2.5 1.8 2 1 0 2 2 2 0 Adaptin N terminal region DRIM PF07539.12 PXF43521.1 - 0.096 11.0 1.4 0.49 8.6 0.5 2.0 1 1 1 2 2 2 0 Down-regulated in metastasis Roc PF08477.13 PXF43521.1 - 0.11 12.7 0.0 18 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 PXF43521.1 - 0.12 12.0 0.0 12 5.4 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 PXF43521.1 - 0.14 12.1 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 PXF43521.1 - 0.16 10.7 0.1 38 2.9 0.0 3.3 4 0 0 4 4 4 0 Predicted ATPase of the ABC class FUN14 PF04930.15 PXF43522.1 - 1.4e-16 60.7 0.2 2.3e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 FUN14 family Chromo PF00385.24 PXF43524.1 - 4.2e-07 29.8 0.7 9.3e-07 28.7 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Qn_am_d_aII PF14930.6 PXF43526.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Sel1 PF08238.12 PXF43527.1 - 1.3e-21 76.5 0.5 0.00053 20.6 0.0 9.9 11 0 0 11 11 11 4 Sel1 repeat TPR_6 PF13174.6 PXF43527.1 - 0.00083 19.8 2.7 90 4.0 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF43527.1 - 0.02 15.7 21.3 7.2 7.7 0.1 7.8 7 2 3 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF43527.1 - 0.039 14.5 12.3 26 5.4 0.0 6.8 8 1 0 8 8 8 0 Tetratricopeptide repeat YqaH PF17448.2 PXF43527.1 - 0.087 13.1 0.2 5.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized YqaH-like TPR_11 PF13414.6 PXF43527.1 - 1.1 9.0 5.5 1.2 8.9 0.1 3.8 4 0 0 4 4 4 0 TPR repeat AAA_lid_1 PF17857.1 PXF43529.1 - 0.021 15.0 1.3 0.15 12.3 0.3 2.4 2 1 0 2 2 2 0 AAA+ lid domain GST_N_3 PF13417.6 PXF43529.1 - 0.028 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Haem_oxygenas_2 PF14518.6 PXF43530.1 - 3.4e-13 49.7 0.0 4.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF3865 PF12981.7 PXF43530.1 - 0.011 15.7 0.3 0.019 14.8 0.3 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) DUF3452 PF11934.8 PXF43531.1 - 0.01 15.4 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Cas_Cas1 PF01867.16 PXF43531.1 - 0.041 13.0 0.7 0.056 12.6 0.7 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Nse4_C PF08743.10 PXF43531.1 - 0.12 12.6 0.2 1.6 9.0 0.0 2.5 2 1 1 3 3 3 0 Nse4 C-terminal Activator-TraM PF11657.8 PXF43531.1 - 1.3 8.8 7.8 0.38 10.6 4.8 1.6 2 0 0 2 2 2 0 Transcriptional activator TraM Agenet PF05641.12 PXF43532.1 - 0.075 13.5 0.0 3.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Agenet domain An_peroxidase PF03098.15 PXF43534.1 - 7.5e-120 401.0 0.0 8.9e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF247 PF03140.15 PXF43534.1 - 0.052 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function An_peroxidase PF03098.15 PXF43535.1 - 7.5e-120 401.0 0.0 8.9e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF247 PF03140.15 PXF43535.1 - 0.052 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function An_peroxidase PF03098.15 PXF43536.1 - 2.1e-121 406.1 0.0 2.3e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF43537.1 - 5.3e-113 378.4 0.2 5.9e-113 378.2 0.2 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Gly-rich_Ago1 PF12764.7 PXF43538.1 - 0.0038 18.0 0.0 0.0047 17.7 0.0 1.1 1 0 0 1 1 1 1 Glycine-rich region of argonaut EF-hand_1 PF00036.32 PXF43539.1 - 1.5e-05 24.2 0.0 0.00052 19.4 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PXF43539.1 - 0.00048 19.8 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PXF43539.1 - 0.0039 17.6 0.1 0.11 12.9 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair Dockerin_1 PF00404.18 PXF43539.1 - 0.019 15.1 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain OrfB_IS605 PF01385.19 PXF43539.1 - 0.028 14.7 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Probable transposase FlaE PF07559.14 PXF43539.1 - 0.076 13.6 0.0 0.43 11.2 0.0 1.9 2 0 0 2 2 2 0 Flagellar basal body protein FlaE PH_6 PF15406.6 PXF43539.1 - 0.13 12.6 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain An_peroxidase PF03098.15 PXF43541.1 - 1.2e-113 380.6 0.3 1.3e-113 380.4 0.3 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF43542.1 - 1.8e-121 406.3 0.0 2e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF43543.1 - 5e-13 48.5 0.1 5.9e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 Animal haem peroxidase An_peroxidase PF03098.15 PXF43544.1 - 6.2e-119 398.0 0.0 6.9e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase zf-CCCH PF00642.24 PXF43545.1 - 1.1e-19 69.8 13.0 1.1e-09 37.9 2.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PXF43545.1 - 6.3e-07 29.2 16.2 9.3e-05 22.3 4.6 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PXF43545.1 - 2.3e-06 27.2 12.7 6.2e-05 22.7 2.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Gag_p30 PF02093.16 PXF43545.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Gag P30 core shell protein zf-CCCH_2 PF14608.6 PXF43545.1 - 0.029 14.9 6.4 0.28 11.7 0.3 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PXF43545.1 - 4.6 8.0 13.7 0.89 10.3 1.4 2.7 2 1 1 3 3 3 0 Torus domain Chromo PF00385.24 PXF43546.1 - 2.1e-05 24.3 0.0 0.00022 21.1 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain cobW PF02492.19 PXF43549.1 - 1.4e-57 194.1 3.9 2.6e-51 173.7 1.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PXF43549.1 - 3.4e-41 139.1 0.1 4e-19 68.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 PXF43549.1 - 0.0068 16.3 0.1 0.17 11.8 0.1 3.0 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 PXF43549.1 - 0.0071 16.9 0.0 0.31 11.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PXF43549.1 - 0.017 15.5 0.1 0.54 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PXF43549.1 - 0.048 14.2 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PXF43549.1 - 0.065 13.3 0.1 0.38 10.8 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 PXF43549.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 PXF43549.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 PXF43549.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 PXF43549.1 - 0.11 12.8 0.1 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PXF43549.1 - 0.13 12.2 0.1 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Suf PF05843.14 PXF43549.1 - 0.48 10.4 5.8 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BLOC1_2 PF10046.9 PXF43550.1 - 7.6e-10 39.0 3.8 1.1e-09 38.4 3.3 1.5 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM83 PF07894.12 PXF43550.1 - 0.013 15.1 0.3 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 FAM83 A-H Sec34 PF04136.15 PXF43550.1 - 0.047 13.6 3.9 0.071 13.0 0.8 2.0 1 1 1 2 2 2 0 Sec34-like family BDHCT_assoc PF16204.5 PXF43551.1 - 0.061 13.0 0.1 0.076 12.7 0.1 1.1 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein PA26 PF04636.13 PXF43551.1 - 0.22 10.4 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SNF2_N PF00176.23 PXF43552.1 - 4.7e-61 206.5 0.0 7.6e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 PXF43552.1 - 1.7e-19 69.4 5.0 7e-14 51.5 0.7 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 PXF43552.1 - 2.7e-19 69.6 0.0 7.5e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 PXF43552.1 - 1.6e-08 34.8 0.3 1.6e-08 34.8 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 PXF43552.1 - 6e-08 32.9 0.0 2.8e-07 30.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 PXF43552.1 - 2.3e-05 24.7 0.3 0.00012 22.3 0.3 2.3 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain DEAD PF00270.29 PXF43552.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SLIDE PF09111.10 PXF43552.1 - 0.0035 17.3 0.0 0.018 15.0 0.0 2.3 1 1 0 1 1 1 1 SLIDE ERCC3_RAD25_C PF16203.5 PXF43552.1 - 0.029 13.6 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase FAD_binding_7 PF03441.14 PXF43553.1 - 4.8e-71 238.4 0.0 8.9e-71 237.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PXF43553.1 - 1.7e-41 142.0 0.0 3e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase CPSase_L_D2 PF02786.17 PXF43554.1 - 1.1e-104 348.6 0.1 4.6e-67 225.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 PXF43554.1 - 7.5e-42 142.5 0.1 1.6e-41 141.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 PXF43554.1 - 6.7e-15 55.1 0.1 1.8e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 PXF43554.1 - 2.1e-13 50.3 0.0 1e-12 48.1 0.0 2.3 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 PXF43554.1 - 3.3e-10 39.9 0.1 0.00037 20.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 PXF43554.1 - 3.8e-10 39.6 0.0 0.00031 20.5 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 PXF43554.1 - 2.4e-09 37.0 0.1 0.002 17.7 0.0 3.3 4 1 0 4 4 4 2 ATP-grasp domain ATP-grasp_3 PF02655.14 PXF43554.1 - 4e-08 33.5 0.1 0.00026 21.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 PXF43554.1 - 1e-07 31.7 0.0 0.0001 22.0 0.0 3.3 3 1 0 3 3 3 2 RimK-like ATP-grasp domain GARS_A PF01071.19 PXF43554.1 - 4.8e-07 29.8 0.5 0.011 15.5 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_2 PF08442.10 PXF43554.1 - 2.2e-06 27.4 0.1 0.019 14.6 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 PXF43554.1 - 0.00028 20.4 0.1 0.0039 16.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain B12-binding PF02310.19 PXF43554.1 - 0.018 15.1 0.0 0.75 9.8 0.0 3.2 2 1 0 3 3 3 0 B12 binding domain Epimerase PF01370.21 PXF43554.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WGG PF10273.9 PXF43555.1 - 4.4e-08 33.7 0.0 7.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 MDMPI_N PF11716.8 PXF43555.1 - 0.015 16.0 0.2 0.025 15.3 0.2 1.5 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain ACC_epsilon PF13822.6 PXF43555.1 - 0.38 11.5 0.1 0.38 11.5 0.1 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Thioredoxin PF00085.20 PXF43556.1 - 6.9e-61 202.7 0.5 1.7e-30 105.1 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 PXF43556.1 - 7.4e-34 117.3 4.1 1.3e-23 83.9 0.4 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PXF43556.1 - 2.6e-10 40.7 3.1 3.2e-05 24.3 0.2 4.9 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF43556.1 - 3.4e-07 30.3 0.0 0.034 14.3 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 PXF43556.1 - 5.9e-07 29.7 0.1 0.8 10.1 0.0 4.5 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 PXF43556.1 - 3.7e-05 23.7 0.0 0.022 14.8 0.0 3.4 4 0 0 4 4 4 1 Thioredoxin domain AhpC-TSA PF00578.21 PXF43556.1 - 4.3e-05 23.4 0.1 0.026 14.4 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Glutaredoxin PF00462.24 PXF43556.1 - 0.00013 22.1 0.0 0.57 10.4 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin TraF PF13728.6 PXF43556.1 - 0.00023 21.1 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 PXF43556.1 - 0.0031 17.4 0.0 6.3 6.8 0.0 3.3 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 PXF43556.1 - 0.0043 16.8 0.0 0.73 9.5 0.0 2.7 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 PXF43556.1 - 0.018 14.8 0.0 0.43 10.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin FBD PF08387.10 PXF43556.1 - 0.033 14.1 0.2 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 FBD peroxidase PF00141.23 PXF43557.1 - 6.7e-49 166.6 0.0 1.3e-48 165.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase SRPRB PF09439.10 PXF43558.1 - 2.2e-24 85.9 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PXF43558.1 - 9.4e-08 31.7 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PXF43558.1 - 2.9e-05 23.7 0.0 7.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PXF43558.1 - 4.9e-05 22.8 0.0 6.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF43558.1 - 0.0022 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ham1p_like PF01725.16 PXF43559.1 - 4.3e-55 186.5 0.0 4.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SWIRM-assoc_2 PF16496.5 PXF43560.1 - 1.2e-63 215.4 1.7 1.2e-63 215.4 1.7 2.8 1 1 2 3 3 3 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 PXF43560.1 - 9.9e-30 102.7 0.1 2.1e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 PXF43560.1 - 7.4e-11 42.1 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF43560.1 - 1e-08 35.3 0.3 3.1e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 PXF43560.1 - 1.3e-06 28.1 5.5 2.6e-06 27.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM-assoc_3 PF16498.5 PXF43560.1 - 0.12 12.7 2.4 0.41 10.9 2.4 2.0 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal C1_2 PF03107.16 PXF43560.1 - 1.3 9.4 5.4 2.5 8.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain Raftlin PF15250.6 PXF43561.1 - 0.29 9.8 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Raftlin ABC2_membrane PF01061.24 PXF43562.1 - 2.7e-42 144.6 11.8 3.7e-42 144.1 11.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PXF43562.1 - 2.4e-24 86.4 0.0 3.8e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PXF43562.1 - 3.8e-06 27.4 0.0 7.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PXF43562.1 - 0.00019 21.4 0.5 0.11 12.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PXF43562.1 - 0.00026 20.9 0.1 0.00049 20.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PXF43562.1 - 0.00032 20.2 0.1 0.0007 19.1 0.1 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF43562.1 - 0.0011 19.3 0.1 0.0024 18.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF43562.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sep15_SelM PF08806.11 PXF43562.1 - 0.0043 17.2 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 1 1 Sep15/SelM redox domain ABC2_membrane_3 PF12698.7 PXF43562.1 - 0.0057 15.8 12.5 0.011 14.8 12.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_28 PF13521.6 PXF43562.1 - 0.0071 16.6 0.0 0.021 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 PXF43562.1 - 0.017 15.1 0.2 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 PXF43562.1 - 0.017 14.8 0.3 0.038 13.7 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 PXF43562.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 PXF43562.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 PXF43562.1 - 0.055 13.4 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 PXF43562.1 - 0.058 13.5 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 PXF43562.1 - 0.059 13.3 0.1 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 PXF43562.1 - 0.061 13.0 0.0 0.069 12.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 PXF43562.1 - 0.062 12.5 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 PXF43562.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 PXF43562.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 PXF43562.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 PXF43562.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PXF43562.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 PXF43562.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 PXF43562.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PXF43562.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain PIF1 PF05970.14 PXF43562.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 PXF43562.1 - 0.17 11.2 0.2 0.36 10.1 0.0 1.6 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 PXF43562.1 - 0.18 12.2 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF43562.1 - 0.21 11.3 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cytochrom_B_C PF00032.17 PXF43562.1 - 0.21 11.9 2.4 0.44 10.9 0.0 2.5 3 0 0 3 3 2 0 Cytochrome b(C-terminal)/b6/petD PDR_assoc PF08370.11 PXF43562.1 - 0.24 11.2 0.1 0.24 11.2 0.1 2.4 2 0 0 2 2 1 0 Plant PDR ABC transporter associated DLIC PF05783.11 PXF43562.1 - 0.26 10.1 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF702 PF05142.12 PXF43563.1 - 0.013 16.0 4.6 0.03 14.8 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) RNase_Zc3h12a PF11977.8 PXF43564.1 - 4.9e-15 55.6 0.2 8.3e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF3450 PF11932.8 PXF43564.1 - 0.009 15.3 0.5 0.038 13.3 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) ATG16 PF08614.11 PXF43564.1 - 0.07 13.3 5.6 0.14 12.4 5.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.12 PXF43564.1 - 0.24 11.6 2.4 0.36 11.0 1.4 1.8 2 0 0 2 2 2 0 MbeD/MobD like DDE_1 PF03184.19 PXF43565.1 - 6.7e-22 78.0 0.1 3.4e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF43565.1 - 4.1e-06 26.7 0.3 7.9e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AAA_33 PF13671.6 PXF43567.1 - 0.00017 21.8 0.0 0.00087 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain PyocinActivator PF11112.8 PXF43567.1 - 0.049 13.8 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Pyocin activator protein PrtN SKI PF01202.22 PXF43567.1 - 0.059 13.5 0.0 0.96 9.6 0.0 2.3 2 1 0 2 2 2 0 Shikimate kinase RNase_Zc3h12a PF11977.8 PXF43568.1 - 6.4e-21 74.8 0.0 1.1e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 PXF43568.1 - 3.6e-05 23.4 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-only RNase P DUF5521 PF17659.1 PXF43568.1 - 0.35 8.7 3.0 0.49 8.2 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) CCDC50_N PF15295.6 PXF43568.1 - 1.7 8.8 7.9 0.17 12.1 3.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus P5CR_dimer PF14748.6 PXF43569.1 - 5.9e-40 135.7 1.5 1e-39 134.9 1.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PXF43569.1 - 2.4e-14 53.7 0.0 5.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Thioredoxin PF00085.20 PXF43570.1 - 1.3e-55 185.7 0.3 9.2e-26 89.8 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 PXF43570.1 - 5.7e-30 104.6 2.7 1.2e-21 77.4 0.5 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PXF43570.1 - 5.1e-07 30.1 5.1 0.045 14.2 0.5 5.1 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF43570.1 - 1.1e-06 28.7 0.0 0.049 13.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Glutaredoxin PF00462.24 PXF43570.1 - 2.8e-05 24.2 0.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_8 PF13905.6 PXF43570.1 - 4.3e-05 23.8 0.3 0.73 10.2 0.0 4.2 4 1 1 5 5 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 PXF43570.1 - 0.0001 22.3 0.0 0.069 13.2 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin domain AhpC-TSA PF00578.21 PXF43570.1 - 0.00021 21.2 0.1 0.16 11.9 0.1 2.9 2 1 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 PXF43570.1 - 0.0018 18.0 0.0 0.77 9.5 0.0 2.6 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 PXF43570.1 - 0.0087 16.0 0.0 3.4 7.7 0.0 3.4 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE FBD PF08387.10 PXF43570.1 - 0.013 15.3 0.1 0.99 9.3 0.0 2.7 2 0 0 2 2 2 0 FBD Thioredoxin_9 PF14595.6 PXF43570.1 - 0.032 14.0 0.0 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin TraF PF13728.6 PXF43570.1 - 0.043 13.6 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Citrate_synt PF00285.21 PXF43572.1 - 1.3e-20 73.8 0.0 1.9e-18 66.7 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 PXF43572.1 - 1.1e-11 44.8 0.3 2e-11 44.0 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PXF43572.1 - 3.3e-07 30.2 0.2 1.5e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Cofac_haem_bdg PF04187.13 PXF43573.1 - 7.1e-45 153.6 0.0 9.5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN DUF4368 PF14287.6 PXF43573.1 - 0.023 15.0 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Mis12 PF05859.12 PXF43574.1 - 0.0062 16.6 2.5 0.64 10.1 0.0 2.3 2 0 0 2 2 2 2 Mis12 protein TrbI_Ftype PF09677.10 PXF43574.1 - 0.29 11.5 1.7 1.3 9.3 0.0 2.6 3 1 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) Rep_fac-A_C PF08646.10 PXF43574.1 - 0.77 9.5 4.0 1.3 8.7 4.0 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain Tic22 PF04278.12 PXF43576.1 - 2.2e-19 69.8 0.0 3.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Tic22-like family Pentapeptide PF00805.22 PXF43577.1 - 4.6e-15 54.9 8.6 2.2e-08 33.5 0.8 3.0 2 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 PXF43577.1 - 4.9e-09 36.2 9.5 1e-07 32.0 2.5 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 PXF43577.1 - 1.5e-07 31.5 1.2 4.1e-07 30.1 1.3 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) PseudoU_synth_2 PF00849.22 PXF43578.1 - 4.9e-34 117.7 0.0 1e-33 116.7 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Snf7 PF03357.21 PXF43580.1 - 3.9e-32 111.2 20.1 4.8e-32 110.9 20.1 1.1 1 0 0 1 1 1 1 Snf7 T2SSM_b PF10741.9 PXF43580.1 - 0.0064 16.3 1.5 2.9 7.7 0.2 2.4 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein M subtype b Ist1 PF03398.14 PXF43580.1 - 0.054 13.4 6.0 0.073 13.0 6.0 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PRIMA1 PF16101.5 PXF43580.1 - 0.3 11.1 1.6 0.57 10.2 1.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 YlqD PF11068.8 PXF43580.1 - 2.3 8.6 17.9 2.8e+03 -1.4 17.8 2.3 1 1 0 1 1 1 0 YlqD protein Pkinase PF00069.25 PXF43581.1 - 3.2e-10 39.8 0.0 3.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF43581.1 - 0.00087 19.3 0.1 0.00087 19.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF43581.1 - 0.0052 16.4 0.1 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PIP49_C PF12260.8 PXF43581.1 - 0.0075 15.9 0.0 0.0083 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 PXF43581.1 - 0.018 14.3 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Snf7 PF03357.21 PXF43582.1 - 1.7e-31 109.1 20.1 2.1e-31 108.8 20.1 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 PXF43582.1 - 0.024 14.6 6.0 0.032 14.2 6.0 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Alkyl_sulf_dimr PF14863.6 PXF43582.1 - 1.5 9.3 4.7 8.3 6.9 1.2 2.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation YlqD PF11068.8 PXF43582.1 - 1.6 9.1 17.4 3.6 8.0 3.1 2.3 1 1 1 2 2 2 0 YlqD protein Pro_isomerase PF00160.21 PXF43583.1 - 1.2e-27 97.1 0.2 1.6e-27 96.7 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LON_substr_bdg PF02190.16 PXF43585.1 - 0.0065 16.4 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Cytochrom_B561 PF03188.16 PXF43586.1 - 8.7e-19 68.0 10.0 1.7e-18 67.1 10.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Na_H_Exchanger PF00999.21 PXF43586.1 - 0.0024 16.7 8.3 0.0024 16.7 8.3 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4079 PF13301.6 PXF43586.1 - 0.0038 17.4 11.2 0.075 13.2 11.2 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Serinc PF03348.15 PXF43586.1 - 0.0089 15.0 2.1 0.013 14.4 2.1 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1761 PF08570.10 PXF43586.1 - 0.04 14.2 0.8 0.04 14.2 0.8 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1761) Sigma_reg_N PF13800.6 PXF43586.1 - 0.16 12.3 0.1 0.52 10.6 0.1 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal LMBR1 PF04791.16 PXF43586.1 - 0.36 9.7 0.0 0.36 9.7 0.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein SLC3A2_N PF16028.5 PXF43586.1 - 4.9 6.8 5.8 6.4 6.4 2.4 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF2530 PF10745.9 PXF43586.1 - 9.2 6.6 9.2 0.3 11.4 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Pro_isomerase PF00160.21 PXF43587.1 - 8.5e-41 139.9 0.0 1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 PXF43588.1 - 3.7e-10 39.9 3.3 6.4e-10 39.2 3.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PXF43588.1 - 9.3e-10 38.7 4.9 1.6e-09 37.9 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF43588.1 - 6.7e-09 35.6 3.3 1.2e-08 34.8 0.7 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF43588.1 - 1.4e-07 31.4 0.5 2.4e-07 30.7 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PXF43588.1 - 2.9e-07 30.2 4.6 4.7e-07 29.6 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF43588.1 - 6.7e-07 28.9 2.0 6.7e-07 28.9 2.0 2.4 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF43588.1 - 4.4e-06 26.4 4.2 9.2e-06 25.4 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF43588.1 - 5.5e-05 23.0 4.2 9.5e-05 22.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PXF43588.1 - 0.00012 22.1 2.3 0.00038 20.5 2.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PXF43588.1 - 0.00098 18.9 2.6 0.0015 18.3 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF43588.1 - 0.00099 18.9 4.3 0.011 15.6 4.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 PXF43588.1 - 0.0099 16.0 2.1 0.022 14.9 2.1 1.6 1 1 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 PXF43588.1 - 0.022 14.6 2.2 0.063 13.1 2.4 1.6 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 PXF43588.1 - 0.034 14.3 1.6 6.5 7.0 0.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 PXF43588.1 - 0.076 13.5 1.7 4.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Pellino PF04710.14 PXF43588.1 - 0.11 11.1 0.6 0.16 10.6 0.6 1.2 1 0 0 1 1 1 0 Pellino zf-RING_4 PF14570.6 PXF43588.1 - 0.15 11.8 4.1 2.6 7.9 0.1 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TniQ PF06527.11 PXF43588.1 - 0.17 12.6 2.3 5.2 7.8 2.3 2.3 1 1 0 1 1 1 0 TniQ PHD PF00628.29 PXF43588.1 - 0.26 11.2 3.8 0.71 9.8 3.9 1.8 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 PXF43588.1 - 0.32 11.1 2.7 7.4 6.7 0.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 PXF43588.1 - 0.54 9.9 4.8 1.2 8.8 4.8 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 PXF43588.1 - 1 9.7 4.6 17 5.8 0.9 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 PXF43588.1 - 3.9 7.5 7.4 3.8 7.5 3.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Amidohydro_2 PF04909.14 PXF43589.1 - 1.5e-34 120.2 1.3 1.6e-34 120.0 1.3 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 PXF43589.1 - 7.4e-06 25.5 0.2 0.00012 21.5 0.2 2.0 1 1 0 1 1 1 1 TatD related DNase DUF782 PF05614.11 PXF43589.1 - 0.078 13.4 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) NAD_binding_2 PF03446.15 PXF43589.1 - 0.21 11.8 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RsfS PF02410.15 PXF43590.1 - 6.3e-23 81.1 0.3 1.1e-22 80.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Integrase_H2C2 PF17921.1 PXF43591.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain PG_binding_1 PF01471.18 PXF43592.1 - 1.1e-12 47.9 0.1 1.8e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain CD99L2 PF12301.8 PXF43592.1 - 0.064 13.5 2.4 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 PG_binding_3 PF09374.10 PXF43592.1 - 0.19 12.0 0.1 2 8.7 0.0 2.5 2 1 1 3 3 3 0 Predicted Peptidoglycan domain Troponin-I_N PF11636.8 PXF43592.1 - 3.9 7.5 12.3 2.3 8.2 7.4 2.4 2 0 0 2 2 2 0 Troponin I residues 1-32 Myb_DNA-binding PF00249.31 PXF43594.1 - 1.1e-27 96.0 1.6 1.8e-14 53.6 1.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF43594.1 - 3.3e-20 72.1 0.1 7.8e-14 51.7 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 PXF43594.1 - 0.00087 19.3 0.8 0.089 12.9 0.0 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 PXF43594.1 - 0.0049 16.7 0.0 1.4 8.9 0.0 2.2 1 1 1 2 2 2 2 Myb DNA-binding like zf-Nse PF11789.8 PXF43597.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Ntox21 PF15526.6 PXF43600.1 - 0.041 14.2 0.2 0.77 10.1 0.0 2.1 1 1 1 2 2 2 0 Novel toxin 21 Caudal_act PF04731.12 PXF43600.1 - 0.089 13.2 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Caudal like protein activation region VMA21 PF09446.10 PXF43605.1 - 2.5e-05 24.3 7.2 3.1e-05 24.0 7.2 1.1 1 0 0 1 1 1 1 VMA21-like domain SDF PF00375.18 PXF43605.1 - 0.013 14.5 0.0 0.016 14.3 0.0 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Claudin_2 PF13903.6 PXF43605.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TrmO PF01980.16 PXF43606.1 - 7.4e-26 90.7 0.0 1.6e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O ABC_tran PF00005.27 PXF43607.1 - 4.2e-24 85.6 0.0 9.3e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PXF43607.1 - 2.1e-17 63.3 20.9 4e-17 62.4 21.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PXF43607.1 - 8.2e-07 29.1 0.2 0.003 17.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PXF43607.1 - 7e-05 22.5 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF43607.1 - 0.0023 18.5 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PXF43607.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PXF43607.1 - 0.012 15.0 0.2 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 PXF43607.1 - 0.021 14.3 15.7 0.026 13.9 13.4 2.1 2 0 0 2 2 2 0 ABC-2 type transporter AAA_16 PF13191.6 PXF43607.1 - 0.091 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 PXF43607.1 - 0.16 12.1 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArdA PF07275.11 PXF43607.1 - 0.17 12.5 0.4 0.48 11.0 0.1 1.8 2 0 0 2 2 2 0 Antirestriction protein (ArdA) ABC2_membrane_3 PF12698.7 PXF43609.1 - 7.1e-24 84.5 8.7 1e-23 84.1 8.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 PXF43609.1 - 1e-23 84.4 0.0 2.1e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF43609.1 - 7.9e-08 32.5 1.9 5.3e-06 26.5 0.0 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF43609.1 - 0.037 13.5 0.1 0.45 9.9 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DEAD PF00270.29 PXF43609.1 - 0.082 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF4162 PF13732.6 PXF43609.1 - 0.16 12.7 0.0 0.46 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Plus-3 PF03126.18 PXF43610.1 - 1.6e-18 67.2 0.0 5.7e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain Paralemmin PF03285.15 PXF43610.1 - 0.007 16.0 2.4 0.012 15.2 2.4 1.3 1 0 0 1 1 1 1 Paralemmin eIF-3_zeta PF05091.12 PXF43612.1 - 1.3e-168 562.3 0.0 1.5e-168 562.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NMD3 PF04981.13 PXF43613.1 - 2.3e-79 266.3 1.9 3.2e-79 265.8 1.9 1.2 1 0 0 1 1 1 1 NMD3 family DUF1289 PF06945.13 PXF43613.1 - 0.0054 16.5 2.8 0.48 10.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1289) HNHc_6 PF16784.5 PXF43613.1 - 0.01 15.4 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 0 Putative HNHc nuclease AAA_6 PF12774.7 PXF43614.1 - 1.7e-99 332.9 0.0 4.3e-99 331.6 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PXF43614.1 - 1.1e-58 199.3 0.0 1.1e-58 199.3 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PXF43614.1 - 5.7e-53 179.9 0.1 2.4e-51 174.5 0.0 3.3 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 PXF43614.1 - 1.8e-42 145.7 5.8 1.8e-42 145.7 5.8 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 PXF43614.1 - 1.3e-35 122.5 0.0 1.6e-27 96.2 0.0 4.5 5 0 0 5 5 5 3 P-loop containing dynein motor region MT PF12777.7 PXF43614.1 - 9.4e-31 107.1 4.6 1.6e-30 106.3 4.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 PXF43614.1 - 1.3e-30 106.2 0.0 4.1e-10 39.8 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_9 PF12781.7 PXF43614.1 - 1.2e-29 103.0 0.7 2.7e-28 98.6 0.0 3.4 3 1 0 3 3 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PXF43614.1 - 1.5e-13 50.9 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 PXF43614.1 - 3.2e-13 50.2 0.0 0.02 15.4 0.0 5.5 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF43614.1 - 1.8e-10 41.2 13.0 0.0092 16.3 0.0 8.3 8 1 0 8 8 6 2 AAA domain Dynein_C PF18199.1 PXF43614.1 - 3.9e-10 39.5 0.0 1.1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_18 PF13238.6 PXF43614.1 - 6.1e-08 33.3 0.2 4.1 8.0 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.6 PXF43614.1 - 2.7e-07 31.1 5.7 0.11 12.8 0.0 6.7 5 1 1 6 6 5 1 AAA ATPase domain AAA_33 PF13671.6 PXF43614.1 - 2.8e-06 27.5 0.9 2 8.5 0.0 5.3 5 0 0 5 5 4 2 AAA domain ABC_tran PF00005.27 PXF43614.1 - 3.6e-05 24.3 2.6 0.35 11.4 0.0 5.2 6 0 0 6 6 4 1 ABC transporter Rad17 PF03215.15 PXF43614.1 - 7.5e-05 22.7 0.4 0.42 10.5 0.1 4.2 5 0 0 5 5 4 1 Rad17 P-loop domain AAA_3 PF07726.11 PXF43614.1 - 0.00013 21.8 0.0 0.0056 16.6 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PXF43614.1 - 0.00026 20.8 0.0 0.035 13.9 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 PXF43614.1 - 0.00054 20.3 0.1 6.2 7.3 0.0 4.3 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 PXF43614.1 - 0.00062 19.5 0.3 16 5.2 0.2 4.4 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 PXF43614.1 - 0.0013 18.1 0.5 0.43 9.9 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 PXF43614.1 - 0.0017 18.0 0.4 0.93 9.3 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_14 PF13173.6 PXF43614.1 - 0.0021 18.1 0.0 6.1 6.9 0.0 4.6 4 0 0 4 4 3 0 AAA domain Dynein_heavy PF03028.15 PXF43614.1 - 0.0036 17.4 0.1 0.55 10.3 0.0 4.0 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 PXF43614.1 - 0.006 16.3 0.0 0.69 9.6 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.6 PXF43614.1 - 0.0081 16.5 2.6 43 4.4 0.0 5.5 7 0 0 7 7 4 0 AAA domain AAA_28 PF13521.6 PXF43614.1 - 0.013 15.8 0.4 34 4.6 0.0 4.5 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 PXF43614.1 - 0.013 14.6 0.1 1.2 8.1 0.0 2.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 PXF43614.1 - 0.055 12.8 0.5 36 3.6 0.0 4.4 5 0 0 5 5 4 0 FtsK/SpoIIIE family AAA_24 PF13479.6 PXF43614.1 - 0.067 12.9 6.3 1 9.1 0.0 4.8 6 0 0 6 6 4 0 AAA domain AAA_25 PF13481.6 PXF43614.1 - 0.12 12.0 0.1 7.9 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain LsmAD PF06741.13 PXF43614.1 - 0.16 12.5 0.4 0.88 10.2 0.4 2.3 1 0 0 1 1 1 0 LsmAD domain CpcD PF01383.21 PXF43615.1 - 7.1e-10 39.0 0.5 1.1e-09 38.4 0.5 1.3 1 0 0 1 1 1 1 CpcD/allophycocyanin linker domain Hydrolase_4 PF12146.8 PXF43616.1 - 2.1e-42 145.1 0.0 2.6e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF43616.1 - 1.6e-12 47.6 0.5 4.1e-08 33.2 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF43616.1 - 3.1e-08 34.5 0.0 3.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PXF43616.1 - 0.00036 20.1 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PXF43616.1 - 0.0011 18.8 0.5 0.14 11.9 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 PXF43616.1 - 0.0033 17.3 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 PXF43616.1 - 0.0041 16.9 0.1 0.0082 15.9 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_4 PF08386.10 PXF43616.1 - 0.0041 17.2 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_2 PF02230.16 PXF43616.1 - 0.0045 16.8 0.3 0.13 12.1 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 PXF43616.1 - 0.045 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Cutinase Staph_haemo PF05480.11 PXF43616.1 - 0.047 13.5 0.2 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Staphylococcus haemolytic protein PAF-AH_p_II PF03403.13 PXF43616.1 - 0.048 12.2 0.1 9.3 4.6 0.0 2.5 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 PXF43616.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 PXF43616.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S10 PF00450.22 PXF43616.1 - 0.092 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase Chlorophyllase2 PF12740.7 PXF43616.1 - 0.094 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2505 PF10698.9 PXF43617.1 - 1.6e-09 38.1 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) Sec5 PF15469.6 PXF43618.1 - 5.1e-05 23.2 0.1 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 PXF43618.1 - 0.022 14.8 0.5 4.4 7.5 0.1 3.2 2 0 0 2 2 2 0 Vps51/Vps67 Nucleotid_trans PF03407.16 PXF43618.1 - 0.025 14.6 0.1 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase COG5 PF10392.9 PXF43618.1 - 3.2 7.9 11.7 2.6 8.2 0.5 3.8 3 2 2 5 5 5 0 Golgi transport complex subunit 5 SecA_DEAD PF07517.14 PXF43619.1 - 1.4e-111 372.4 0.6 3e-111 371.4 0.6 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 PXF43619.1 - 6.6e-44 150.4 2.8 2.9e-42 145.0 1.0 2.8 3 0 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 PXF43619.1 - 3.5e-32 111.4 0.0 1.2e-31 109.6 0.0 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 PXF43619.1 - 8.9e-07 28.8 0.1 4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43619.1 - 0.018 15.4 0.1 3.8 7.9 0.0 3.4 4 0 0 4 4 4 0 Helicase conserved C-terminal domain ResIII PF04851.15 PXF43619.1 - 0.035 14.1 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSF PF00482.23 PXF43619.1 - 0.036 14.0 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F FlgM PF04316.13 PXF43619.1 - 0.26 11.7 2.0 0.52 10.7 0.1 2.6 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Mito_carr PF00153.27 PXF43620.1 - 7.4e-47 157.2 0.7 7.7e-23 80.2 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 PXF43620.1 - 0.0067 15.6 0.0 0.18 10.9 0.0 2.2 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Aconitase PF00330.20 PXF43621.1 - 3.3e-79 267.0 0.2 5.9e-77 259.6 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) GDP_Man_Dehyd PF16363.5 PXF43626.1 - 9.9e-13 48.2 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF43626.1 - 3.1e-05 23.5 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF43627.1 - 1.5e-07 31.2 0.0 2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF43627.1 - 2.4e-05 23.9 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PXF43627.1 - 0.0056 15.8 0.0 0.0072 15.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein T3SS_ATPase_C PF18269.1 PXF43629.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain DUF4127 PF13552.6 PXF43629.1 - 0.085 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Helicase_C_2 PF13307.6 PXF43631.1 - 2.4e-29 102.7 0.0 4.4e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF4157 PF13699.6 PXF43632.1 - 0.033 14.4 1.4 0.052 13.8 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Exo_endo_phos_2 PF14529.6 PXF43634.1 - 6.4e-10 38.9 0.0 7.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF43634.1 - 1.5e-05 24.6 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4796 PF16044.5 PXF43637.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) SRF-TF PF00319.18 PXF43637.1 - 0.15 11.6 0.2 0.32 10.5 0.2 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Transposase_21 PF02992.14 PXF43641.1 - 2e-09 37.0 1.3 8.7e-09 34.9 0.1 2.0 2 0 0 2 2 2 1 Transposase family tnp2 Biotin_carb_N PF00289.22 PXF43644.1 - 1.2e-14 54.8 0.0 1.3e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain zf-C3HC PF07967.13 PXF43646.1 - 1.4e-08 34.9 1.2 4.7e-08 33.1 0.0 2.6 1 1 1 2 2 2 1 C3HC zinc finger-like ABC2_membrane_3 PF12698.7 PXF43646.1 - 1.4 8.0 5.4 3.9 6.5 5.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein NAD_binding_10 PF13460.6 PXF43648.1 - 7.7e-18 65.0 0.0 9.6e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 PXF43648.1 - 1.1e-05 25.5 0.0 2.2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 PXF43648.1 - 0.0012 19.1 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 PXF43648.1 - 0.0016 18.0 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PXF43648.1 - 0.0045 16.6 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DUF2235 PF09994.9 PXF43650.1 - 7e-65 219.2 0.0 8.6e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF659 PF04937.15 PXF43652.1 - 1.3e-19 70.5 0.1 2.2e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) EXOSC1 PF10447.9 PXF43653.1 - 0.04 14.5 0.3 2.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Zn_ribbon_SprT PF17283.2 PXF43654.1 - 0.32 10.9 8.1 0.1 12.5 3.7 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Rhomboid PF01694.22 PXF43655.1 - 3.6e-20 72.5 10.8 3.6e-20 72.5 10.8 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 PXF43655.1 - 0.42 11.2 7.9 0.057 14.0 3.2 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Dimer_Tnp_hAT PF05699.14 PXF43656.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region HA PF03457.14 PXF43657.1 - 2.1e-06 27.9 0.8 3.9 7.9 0.0 4.6 5 0 0 5 5 5 3 Helicase associated domain CENP-X PF09415.10 PXF43657.1 - 0.057 13.7 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RabGAP-TBC PF00566.18 PXF43658.1 - 1.8e-48 165.0 0.0 2.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mob_synth_C PF06463.13 PXF43659.1 - 1.1e-38 132.0 0.0 1.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PXF43659.1 - 1.5e-13 51.5 0.0 2.1e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 PXF43659.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 PXF43659.1 - 0.22 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Amino_oxidase PF01593.24 PXF43660.1 - 4.9e-49 167.8 0.0 5.5e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF43660.1 - 1.2e-07 31.9 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PXF43660.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PXF43660.1 - 0.069 12.7 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Polyketide_cyc2 PF10604.9 PXF43661.1 - 8.9e-11 42.2 0.0 9.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 PXF43661.1 - 0.0011 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 PXF43661.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport TIP49 PF06068.13 PXF43662.1 - 1.8e-154 514.2 1.7 3.1e-154 513.4 1.7 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PXF43662.1 - 4e-22 78.1 0.7 1e-21 76.8 0.7 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PXF43662.1 - 1.8e-09 38.1 3.8 1.7e-06 28.5 0.1 3.9 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 PXF43662.1 - 1.7e-07 30.8 0.6 3.6e-07 29.8 0.6 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 PXF43662.1 - 1.3e-06 28.3 1.1 0.00075 19.3 0.1 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PXF43662.1 - 5.4e-06 26.9 0.4 1.5e-05 25.5 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PXF43662.1 - 5.7e-05 23.1 0.2 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF43662.1 - 9.2e-05 22.7 0.1 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 PXF43662.1 - 0.00028 20.6 0.1 0.038 13.7 0.1 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 PXF43662.1 - 0.00041 20.3 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 PXF43662.1 - 0.00065 19.3 0.1 0.0023 17.5 0.2 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PXF43662.1 - 0.00093 18.6 3.1 0.0032 16.9 0.4 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 PXF43662.1 - 0.0014 18.1 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 PXF43662.1 - 0.0014 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 PXF43662.1 - 0.0019 17.5 0.3 0.0041 16.4 0.3 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 PXF43662.1 - 0.0027 18.0 2.8 0.087 13.2 2.8 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PXF43662.1 - 0.0076 16.0 1.4 0.049 13.4 0.5 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PXF43662.1 - 0.0087 15.5 1.4 0.014 14.8 0.3 1.9 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 PXF43662.1 - 0.01 15.6 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 PXF43662.1 - 0.011 16.2 0.2 0.023 15.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PXF43662.1 - 0.016 14.9 0.2 0.15 11.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 PXF43662.1 - 0.032 14.5 0.8 0.13 12.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PXF43662.1 - 0.033 13.7 0.5 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 PXF43662.1 - 0.042 13.8 0.6 3.2 7.7 0.6 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 PXF43662.1 - 0.048 13.5 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 1 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 PXF43662.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 PXF43662.1 - 0.078 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 PXF43662.1 - 0.081 12.7 0.3 0.25 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 PXF43662.1 - 0.09 12.8 2.3 0.14 12.2 0.4 2.2 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PXF43662.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase APH PF01636.23 PXF43663.1 - 2e-05 24.7 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DnaJ_C PF01556.18 PXF43664.1 - 1.3e-39 135.6 0.0 1.8e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF43664.1 - 1.1e-23 83.1 1.2 2.1e-23 82.2 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PXF43664.1 - 1.9e-12 47.4 16.4 3.5e-12 46.5 16.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PXF43664.1 - 0.7 9.9 16.1 0.42 10.6 4.4 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Fe-S_biosyn PF01521.20 PXF43665.1 - 2e-15 56.9 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HTH_39 PF14090.6 PXF43665.1 - 0.016 15.0 1.4 0.027 14.2 1.4 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5558 PF17713.1 PXF43665.1 - 0.074 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5558) S4 PF01479.25 PXF43666.1 - 5.9e-14 51.5 0.0 1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 PXF43666.1 - 4.3e-05 23.2 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PXF43666.1 - 0.00011 23.0 0.1 0.0002 22.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF1640 PF07798.11 PXF43667.1 - 1.8e-14 54.2 7.2 1.5e-09 38.2 1.8 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) ROK PF00480.20 PXF43667.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 ROK family CBFD_NFYB_HMF PF00808.23 PXF43668.1 - 6.7e-27 93.6 0.3 9.7e-27 93.1 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF43668.1 - 0.0017 18.7 0.1 0.0034 17.7 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PXF43668.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 PXF43668.1 - 0.042 13.9 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 PXF43668.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 PXF43668.1 - 0.12 12.8 0.1 0.24 11.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Peripla_BP_2 PF01497.18 PXF43669.1 - 4.3e-12 46.1 0.0 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein UPF0547 PF10571.9 PXF43669.1 - 0.067 13.3 1.1 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 PXF43669.1 - 0.085 12.3 0.1 0.23 10.9 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain PEP_mutase PF13714.6 PXF43670.1 - 5.1e-44 150.5 0.0 6.5e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 PXF43670.1 - 1.5e-12 46.8 0.7 2.1e-12 46.3 0.7 1.1 1 0 0 1 1 1 1 Isocitrate lyase family NMO PF03060.15 PXF43670.1 - 0.049 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase RPAP3_C PF13877.6 PXF43671.1 - 9.5e-15 54.9 0.1 2.1e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 PXF43671.1 - 3.3e-06 26.7 6.0 0.079 12.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF43671.1 - 0.00017 21.5 6.3 0.0086 16.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF43671.1 - 0.0055 16.4 0.4 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 PXF43671.1 - 0.072 13.7 3.2 5.7 7.7 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF43671.1 - 0.074 13.3 3.1 23 5.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF43671.1 - 0.098 13.0 2.6 14 6.1 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat PPDK_N PF01326.19 PXF43672.1 - 8.3e-31 107.5 9.3 1.7e-30 106.4 4.3 3.0 3 0 0 3 3 3 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 PXF43672.1 - 1.4e-09 37.7 0.9 2.9e-09 36.7 0.9 1.5 1 0 0 1 1 1 1 Starch binding domain AMPK1_CBM PF16561.5 PXF43672.1 - 0.046 13.9 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase SRP1_TIP1 PF00660.17 PXF43672.1 - 0.12 12.5 0.1 0.89 9.7 0.0 2.3 2 0 0 2 2 2 0 Seripauperin and TIP1 family DnaJ_C PF01556.18 PXF43673.1 - 1.5e-40 138.7 0.1 2.1e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF43673.1 - 2.3e-28 98.1 4.6 2.9e-28 97.7 2.8 2.0 2 0 0 2 2 2 1 DnaJ domain Forkhead_N PF08430.12 PXF43673.1 - 0.1 13.2 6.9 0.22 12.1 6.9 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region RPT PF13446.6 PXF43673.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein IMS PF00817.20 PXF43674.1 - 6.4e-29 100.9 0.0 6.8e-28 97.6 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 PXF43674.1 - 9.9e-11 42.4 0.1 6.8e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain RNF220 PF15926.5 PXF43674.1 - 0.0024 17.6 1.4 0.0041 16.8 1.4 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Sec16_C PF12931.7 PXF43675.1 - 1.4e-09 38.0 0.4 7.9e-09 35.6 0.1 2.4 3 1 0 3 3 3 1 Sec23-binding domain of Sec16 WD40 PF00400.32 PXF43675.1 - 1.6e-09 38.2 6.2 0.0024 18.7 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF43675.1 - 8.2e-06 26.0 0.4 2.3 8.6 0.1 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 PXF43675.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 3.3 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) DUF2477 PF10631.9 PXF43675.1 - 0.021 15.5 0.1 0.85 10.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) TPR_2 PF07719.17 PXF43675.1 - 0.37 11.0 1.8 11 6.4 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RRF PF01765.19 PXF43676.1 - 7.3e-61 204.8 6.4 7.3e-61 204.8 6.4 1.5 1 1 1 2 2 2 1 Ribosome recycling factor 14-3-3 PF00244.20 PXF43676.1 - 0.0059 16.1 4.4 0.0059 16.1 4.4 1.6 2 0 0 2 2 2 1 14-3-3 protein Metal_resist PF13801.6 PXF43676.1 - 0.074 13.2 1.0 0.95 9.7 0.3 2.7 1 1 2 3 3 3 0 Heavy-metal resistance Ribosomal_S6 PF01250.17 PXF43676.1 - 0.21 11.9 5.1 0.12 12.7 1.8 2.2 2 1 0 2 2 2 0 Ribosomal protein S6 FmdE PF02663.14 PXF43676.1 - 0.71 9.9 6.1 1.9 8.6 3.0 2.6 2 1 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon YtxH PF12732.7 PXF43676.1 - 5.2 7.7 6.7 17 6.0 4.9 2.3 2 0 0 2 2 2 0 YtxH-like protein Pkinase PF00069.25 PXF43677.1 - 1.8e-50 171.8 0.0 4.6e-50 170.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43677.1 - 1.1e-31 110.1 0.0 5.3e-31 107.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43677.1 - 3e-06 26.7 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ribosomal_60s PF00428.19 PXF43677.1 - 4 8.1 6.6 9.9 6.8 6.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bac_globin PF01152.21 PXF43679.1 - 7.6e-29 100.3 0.3 9.5e-29 100.0 0.3 1.1 1 0 0 1 1 1 1 Bacterial-like globin YafO_toxin PF13957.6 PXF43679.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system DUF2818 PF10993.8 PXF43680.1 - 0.026 15.1 0.1 0.04 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) YjcQ PF09639.10 PXF43680.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 YjcQ protein BolA PF01722.18 PXF43682.1 - 1.7e-27 95.5 0.1 2.1e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein TP6A_N PF04406.14 PXF43683.1 - 1.5e-13 50.5 0.4 3.4e-13 49.4 0.4 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF1601 PF07671.11 PXF43683.1 - 0.012 15.5 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) BLOC1_2 PF10046.9 PXF43684.1 - 1.1e-05 25.6 11.5 0.0069 16.7 0.5 4.5 1 1 2 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 PXF43684.1 - 0.00082 19.8 19.4 0.53 10.8 0.8 5.2 2 1 4 6 6 5 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PXF43684.1 - 0.00087 19.3 16.2 0.047 13.7 1.2 4.7 1 1 4 5 5 5 2 Protein of unknown function (DUF1664) ADIP PF11559.8 PXF43684.1 - 0.0017 18.4 26.6 0.094 12.8 4.6 4.1 2 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 PXF43684.1 - 0.0023 18.0 23.6 1.1 9.4 1.1 4.6 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 PXF43684.1 - 0.003 17.7 23.6 0.34 11.0 7.8 4.1 1 1 3 4 4 4 3 Tropomyosin like TMF_DNA_bd PF12329.8 PXF43684.1 - 0.01 15.8 19.5 0.053 13.5 0.4 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.8 PXF43684.1 - 0.012 16.2 6.8 2.9 8.6 1.0 3.8 4 0 0 4 4 3 0 AT-hook-containing transcription factor Laminin_II PF06009.12 PXF43684.1 - 0.028 14.4 26.8 0.075 13.0 2.5 4.1 1 1 3 4 4 4 0 Laminin Domain II DUF2730 PF10805.8 PXF43684.1 - 0.031 14.3 13.6 0.57 10.3 0.2 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) Spc42p PF11544.8 PXF43684.1 - 0.07 13.1 1.2 9.6 6.3 0.1 3.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p Spc7 PF08317.11 PXF43684.1 - 0.071 12.0 23.9 0.014 14.3 4.7 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein LPP PF04728.13 PXF43684.1 - 0.074 13.5 15.5 9.9 6.6 0.0 6.2 3 2 2 5 5 5 0 Lipoprotein leucine-zipper DUF4709 PF15821.5 PXF43684.1 - 0.079 13.2 10.4 1.7 9.0 1.5 3.8 2 1 1 4 4 3 0 Domain of unknown function (DUF4709) Fib_alpha PF08702.10 PXF43684.1 - 0.094 12.9 20.5 0.52 10.5 5.7 4.0 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 PXF43684.1 - 0.12 12.7 13.0 14 6.1 0.0 5.8 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 PXF43684.1 - 0.13 12.3 23.9 0.33 11.0 2.2 4.3 1 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 PXF43684.1 - 0.13 12.7 14.3 3.2 8.3 1.0 4.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF948 PF06103.11 PXF43684.1 - 0.15 12.3 19.9 0.48 10.7 0.7 4.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 PXF43684.1 - 0.16 12.4 24.9 4.5 7.7 14.5 2.7 1 1 1 2 2 2 0 Fez1 betaPIX_CC PF16523.5 PXF43684.1 - 0.25 11.2 5.4 2.6 7.9 0.4 3.5 2 1 1 3 3 3 0 betaPIX coiled coil Rho_Binding PF08912.11 PXF43684.1 - 0.26 12.1 11.5 14 6.6 0.6 4.4 4 0 0 4 4 4 0 Rho Binding TolA_bind_tri PF16331.5 PXF43684.1 - 0.44 10.7 13.4 11 6.1 0.2 4.3 3 1 0 4 4 4 0 TolA binding protein trimerisation Prefoldin_2 PF01920.20 PXF43684.1 - 0.88 9.6 13.5 5.5 7.0 0.2 4.5 4 1 0 4 4 4 0 Prefoldin subunit Prominin PF05478.11 PXF43684.1 - 1 7.2 16.6 0.27 9.1 11.2 2.2 1 1 2 3 3 3 0 Prominin DUF4140 PF13600.6 PXF43684.1 - 1.1 9.8 25.9 3.6 8.1 2.9 4.6 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 PXF43684.1 - 1.3 9.5 21.5 4.9 7.7 0.7 3.9 1 1 3 4 4 4 0 Apg6 coiled-coil region Csm1_N PF18504.1 PXF43684.1 - 1.4 9.3 22.6 0.24 11.8 1.5 4.8 4 1 1 5 5 5 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 PXF43684.1 - 2.2 8.7 21.0 3.8 7.9 1.9 4.2 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DMPK_coil PF08826.10 PXF43684.1 - 2.6 8.2 8.1 2.4 8.3 0.5 4.1 4 0 0 4 4 4 0 DMPK coiled coil domain like Lzipper-MIP1 PF14389.6 PXF43684.1 - 3 8.2 13.8 1.8 8.9 1.2 3.9 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 FtsX_ECD PF18075.1 PXF43684.1 - 3.6 8.3 6.2 3.1 8.5 0.5 3.3 2 1 0 2 2 2 0 FtsX extracellular domain GP41 PF00517.17 PXF43684.1 - 3.8 7.4 6.4 30 4.4 0.1 3.7 1 1 2 4 4 4 0 Retroviral envelope protein SOGA PF11365.8 PXF43684.1 - 4.1 8.6 11.4 0.99 10.6 0.2 3.7 1 1 4 5 5 5 0 Protein SOGA XhlA PF10779.9 PXF43684.1 - 5.6 7.2 14.8 10 6.4 0.2 4.8 4 2 1 5 5 5 0 Haemolysin XhlA Vps51 PF08700.11 PXF43684.1 - 6.4 6.9 16.4 15 5.8 2.4 5.7 4 3 1 5 5 5 0 Vps51/Vps67 DUF3847 PF12958.7 PXF43684.1 - 6.8 6.9 13.1 1.8 8.7 0.1 4.2 4 2 1 5 5 4 0 Protein of unknown function (DUF3847) SlyX PF04102.12 PXF43684.1 - 7.1 7.3 16.1 40 4.9 0.8 5.3 3 2 1 4 4 4 0 SlyX YscO-like PF16789.5 PXF43684.1 - 7.7 6.5 13.9 0.19 11.8 4.2 2.6 2 1 1 3 3 2 0 YscO-like protein FG-GAP_2 PF14312.6 PXF43685.1 - 5.1e-30 103.5 29.4 2.4e-05 24.5 1.9 7.5 7 0 0 7 7 7 7 FG-GAP repeat DUF1513 PF07433.11 PXF43685.1 - 0.0057 15.8 0.1 1.6 7.7 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1513) Phlebovirus_G2 PF07245.11 PXF43685.1 - 0.055 12.0 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 RCC1_2 PF13540.6 PXF43685.1 - 0.064 13.1 1.0 17 5.4 0.0 3.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DUF4402 PF14352.6 PXF43685.1 - 0.089 13.4 0.2 7.1 7.3 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4402) AhpC-TSA_2 PF13911.6 PXF43685.1 - 0.13 12.4 0.1 6.4 6.9 0.0 2.9 2 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme Kelch_6 PF13964.6 PXF43685.1 - 0.16 12.3 0.2 5.8 7.3 0.2 3.2 4 0 0 4 4 4 0 Kelch motif FG-GAP PF01839.23 PXF43685.1 - 1 9.6 27.6 10 6.4 0.5 6.4 6 0 0 6 6 6 0 FG-GAP repeat UQ_con PF00179.26 PXF43686.1 - 3.5e-48 162.8 0.0 4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF43686.1 - 0.041 13.6 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 PXF43686.1 - 0.082 13.2 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 RWD domain zf-CCCH PF00642.24 PXF43687.1 - 2.5e-09 36.8 2.6 2.5e-09 36.8 2.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 PXF43687.1 - 9.9e-08 31.7 9.9 2e-07 30.7 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF43687.1 - 1.1e-07 31.6 7.0 1.9e-07 30.9 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF43687.1 - 1e-06 28.6 9.7 1.8e-06 27.8 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PXF43687.1 - 2.5e-06 27.7 9.1 5.5e-06 26.6 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PXF43687.1 - 5e-06 26.3 6.9 9.2e-06 25.4 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 PXF43687.1 - 5.4e-06 26.3 4.5 1.1e-05 25.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_UBOX PF13445.6 PXF43687.1 - 1.1e-05 25.3 7.8 0.00024 21.0 2.9 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF43687.1 - 3e-05 23.8 10.5 5.7e-05 22.9 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 PXF43687.1 - 0.00018 21.2 2.8 0.00018 21.2 2.8 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-P11 PF03854.14 PXF43687.1 - 0.00072 19.2 6.1 0.0013 18.3 6.1 1.4 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_10 PF16685.5 PXF43687.1 - 0.0017 18.5 5.2 0.0017 18.5 5.2 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 PXF43687.1 - 0.0021 18.1 6.4 0.011 15.9 6.8 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PXF43687.1 - 0.16 12.3 6.3 0.55 10.6 6.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 PXF43687.1 - 0.16 12.5 2.7 0.4 11.2 2.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 PXF43687.1 - 0.26 11.3 7.4 0.92 9.5 7.7 1.8 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 PXF43687.1 - 0.5 10.4 5.2 1.5 8.9 5.2 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 PXF43687.1 - 1.6 9.1 6.2 3.7 7.9 6.2 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding UQ_con PF00179.26 PXF43688.1 - 2.6e-53 179.5 0.0 2.9e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF43688.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PXF43688.1 - 0.0042 17.4 0.0 0.0052 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 PXF43688.1 - 0.05 13.5 0.1 0.079 12.8 0.1 1.4 1 1 0 1 1 1 0 UEV domain Ras PF00071.22 PXF43689.1 - 9.3e-58 194.4 0.3 1.1e-57 194.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF43689.1 - 7.1e-31 106.9 0.0 1e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF43689.1 - 2.7e-14 53.0 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PXF43689.1 - 8.5e-07 28.6 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PXF43689.1 - 2.1e-05 24.5 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PXF43689.1 - 0.00061 19.9 0.0 0.00085 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PXF43689.1 - 0.0019 18.6 0.0 0.0035 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PXF43689.1 - 0.0086 15.8 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PXF43689.1 - 0.011 15.8 0.0 0.035 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 PXF43689.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PXF43689.1 - 0.014 14.9 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 PXF43689.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 PXF43689.1 - 0.022 15.0 0.1 0.082 13.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PXF43689.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 PXF43689.1 - 0.036 13.2 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 PXF43689.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arb2 PF09757.9 PXF43689.1 - 0.063 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain ABC_tran PF00005.27 PXF43689.1 - 0.066 13.7 0.0 0.096 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter LuxT_C PF18285.1 PXF43689.1 - 0.081 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain FeoB_N PF02421.18 PXF43689.1 - 0.083 12.4 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 PXF43689.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain CNOT11 PF10155.9 PXF43690.1 - 1.5e-40 138.2 1.9 4.3e-40 136.8 0.5 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 ARID PF01388.21 PXF43690.1 - 0.19 12.4 0.0 0.82 10.4 0.0 2.0 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain WD40 PF00400.32 PXF43691.1 - 1.1e-40 136.9 23.9 2e-08 34.7 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF43691.1 - 1.5e-11 44.4 0.2 0.37 11.1 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PXF43691.1 - 1.2e-05 24.0 0.5 0.014 13.9 0.0 2.7 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.6 PXF43691.1 - 0.00019 20.8 0.8 4.8 6.4 0.0 3.7 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 PXF43691.1 - 0.0004 19.2 0.7 0.24 10.1 0.1 3.1 1 1 3 4 4 4 3 Nup133 N terminal like eIF2A PF08662.11 PXF43691.1 - 0.00054 19.9 0.0 0.073 12.9 0.0 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PXF43691.1 - 0.00093 18.2 0.1 0.32 9.9 0.0 3.5 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SET PF00856.28 PXF43692.1 - 3.3e-21 76.4 0.3 1.4e-20 74.3 0.3 2.1 1 1 0 1 1 1 1 SET domain zf-HC5HC2H PF13771.6 PXF43692.1 - 2.1e-16 59.9 17.0 9.3e-10 38.6 2.6 8.7 6 1 1 7 7 7 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PXF43692.1 - 2.4e-13 50.2 21.5 6.2e-10 39.2 7.2 7.6 5 2 1 7 7 7 2 PHD-zinc-finger like domain FYRN PF05964.14 PXF43692.1 - 1.7e-12 47.0 0.0 4.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 PXF43692.1 - 5e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus PHD PF00628.29 PXF43692.1 - 8.5e-08 32.0 88.1 7.3e-06 25.8 4.8 8.9 9 1 1 10 10 10 5 PHD-finger DUF4295 PF14128.6 PXF43692.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) SUIM_assoc PF16619.5 PXF43692.1 - 3.3 7.8 7.1 11 6.2 7.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Rad50_zn_hook PF04423.14 PXF43692.1 - 5.6 6.9 6.0 32 4.5 0.5 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif Myb_DNA-binding PF00249.31 PXF43693.1 - 3.9e-09 36.6 0.0 6.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA12 PF10443.9 PXF43693.1 - 0.014 14.1 0.3 0.024 13.4 0.3 1.2 1 0 0 1 1 1 0 RNA12 protein CDC45 PF02724.14 PXF43693.1 - 0.32 9.2 5.0 0.49 8.6 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase_fungal PF17667.1 PXF43693.1 - 0.52 9.0 6.6 3.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase SLC12 PF03522.15 PXF43693.1 - 5 6.0 11.7 0.32 10.0 5.2 1.9 2 0 0 2 2 2 0 Solute carrier family 12 Dicty_REP PF05086.12 PXF43693.1 - 7.5 4.4 6.0 13 3.6 6.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Striatin PF08232.12 PXF43693.1 - 8.1 7.0 28.0 6.9 7.2 0.2 3.4 2 1 1 3 3 3 0 Striatin family Trypsin_2 PF13365.6 PXF43694.1 - 1.5e-32 113.6 1.1 3.3e-32 112.5 1.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 PXF43694.1 - 1.2e-15 57.5 1.5 3.5e-15 56.1 0.8 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PXF43694.1 - 1.9e-13 50.0 2.9 1.1e-11 44.4 1.5 2.6 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 PXF43694.1 - 3.4e-11 43.4 0.0 7.2e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Trypsin PDZ PF00595.24 PXF43694.1 - 1.5e-07 31.7 1.1 5.1e-06 26.7 0.5 2.6 2 0 0 2 2 2 1 PDZ domain LSM PF01423.22 PXF43694.1 - 0.003 17.2 0.0 0.0081 15.8 0.0 1.7 1 0 0 1 1 1 1 LSM domain Peptidase_S46 PF10459.9 PXF43694.1 - 0.005 15.6 0.0 0.65 8.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S29 PF02907.15 PXF43694.1 - 0.021 14.5 0.1 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease GRASP55_65 PF04495.14 PXF43694.1 - 0.026 14.9 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 PXF43694.1 - 0.042 13.8 0.4 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.21 PXF43694.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease TPR_1 PF00515.28 PXF43695.1 - 2.2e-27 93.7 26.9 2.8e-07 30.1 0.4 8.1 9 1 0 9 9 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 PXF43695.1 - 3.1e-24 85.6 2.1 9.7e-22 77.5 0.3 3.2 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 PXF43695.1 - 1.1e-23 81.4 32.2 5.4e-05 23.0 0.3 9.4 10 2 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 PXF43695.1 - 1.5e-23 81.0 18.0 1.5e-06 28.0 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PXF43695.1 - 1.9e-21 74.9 20.1 8.4e-06 26.2 0.1 8.1 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 PXF43695.1 - 1e-20 73.1 8.3 2.2e-09 36.8 0.1 5.4 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 PXF43695.1 - 5.9e-16 57.6 14.9 0.0041 17.4 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF43695.1 - 2.5e-15 56.8 21.4 3.6e-06 27.5 0.1 7.5 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 PXF43695.1 - 8.5e-15 55.0 17.7 0.00062 20.2 0.4 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 PXF43695.1 - 5.9e-12 45.1 14.2 0.0016 18.2 0.4 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF43695.1 - 1.7e-11 44.2 27.7 0.0028 17.9 0.3 6.9 3 2 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF43695.1 - 1.3e-10 41.3 18.7 0.018 15.3 0.7 5.5 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF43695.1 - 6.5e-09 35.2 19.8 0.0089 16.0 0.1 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF43695.1 - 8.7e-09 35.4 13.9 0.012 15.8 0.3 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 PXF43695.1 - 4e-07 29.5 12.6 0.028 13.6 0.1 4.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 PXF43695.1 - 8.3e-05 23.0 26.1 0.57 10.9 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat ChAPs PF09295.10 PXF43695.1 - 0.015 14.3 0.9 0.22 10.5 0.0 2.9 1 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) GTP_EFTU PF00009.27 PXF43695.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HHH_8 PF14716.6 PXF43695.1 - 0.22 11.9 2.0 9.6 6.7 0.0 3.7 3 1 1 4 4 3 0 Helix-hairpin-helix domain DUF3856 PF12968.7 PXF43695.1 - 0.36 10.9 6.0 0.85 9.7 0.0 3.5 3 1 0 4 4 3 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 PXF43695.1 - 0.48 11.2 3.4 70 4.3 0.3 4.3 3 0 0 3 3 3 0 Sel1 repeat LPMO_10 PF03067.15 PXF43696.1 - 1.3e-21 78.2 4.0 1.3e-21 78.2 4.0 2.4 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FhuF_C PF11575.8 PXF43696.1 - 0.16 11.9 6.9 0.59 10.1 0.1 4.2 4 0 0 4 4 4 0 FhuF 2Fe-2S C-terminal domain Conotoxin PF02950.17 PXF43696.1 - 6.3 7.9 8.6 2.3 9.3 4.9 2.2 1 1 1 2 2 2 0 Conotoxin SAE2 PF08573.10 PXF43697.1 - 0.00038 21.6 2.7 0.0036 18.4 2.7 2.7 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Chromate_transp PF02417.15 PXF43698.1 - 1.6e-47 161.6 44.9 1.2e-25 90.5 16.9 2.4 3 0 0 3 3 3 2 Chromate transporter FKBP_C PF00254.28 PXF43700.1 - 6.7e-11 42.4 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NblA PF04485.12 PXF43701.1 - 1.1e-11 44.9 9.4 1.4e-11 44.6 9.4 1.1 1 0 0 1 1 1 1 Phycobilisome degradation protein nblA dCache_2 PF08269.11 PXF43701.1 - 0.048 12.8 0.2 0.062 12.5 0.2 1.1 1 0 0 1 1 1 0 Cache domain Got1 PF04178.12 PXF43702.1 - 1.2e-16 61.1 11.2 1.6e-16 60.7 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 PXF43702.1 - 0.022 15.1 6.0 0.022 15.1 6.0 1.6 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 PXF43702.1 - 0.67 10.0 13.6 0.98 9.5 2.8 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III OAD_gamma PF04277.13 PXF43702.1 - 5.1 7.8 6.2 3.2 8.4 4.0 1.8 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PCI PF01399.27 PXF43703.1 - 2.6e-12 47.2 1.3 7.6e-12 45.7 0.2 2.1 2 0 0 2 2 2 1 PCI domain Aminotran_1_2 PF00155.21 PXF43704.1 - 2e-45 155.6 0.0 2.3e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PXF43704.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase F-box-like PF12937.7 PXF43705.1 - 0.0015 18.3 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF43705.1 - 0.016 15.0 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain Macoilin PF09726.9 PXF43706.1 - 1.1 7.8 10.3 1.5 7.3 10.3 1.1 1 0 0 1 1 1 0 Macoilin family Abhydrolase_1 PF00561.20 PXF43707.1 - 8.7e-07 28.8 0.1 1.9e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 PXF43707.1 - 0.026 13.3 0.0 0.045 12.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.8 PXF43707.1 - 0.056 12.7 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Helicase_C_2 PF13307.6 PXF43708.1 - 1.4e-53 181.6 0.0 6.4e-53 179.4 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 PXF43708.1 - 6.1e-45 153.0 0.1 1.2e-44 152.1 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 PXF43708.1 - 6.6e-05 23.0 0.4 0.033 14.2 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF43708.1 - 6.9e-05 22.7 0.0 0.0027 17.5 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DENN PF02141.21 PXF43708.1 - 0.067 13.1 0.0 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain HBB PF06777.11 PXF43708.1 - 0.084 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain FoP_duplication PF13865.6 PXF43709.1 - 5.2e-09 36.5 16.1 5.2e-09 36.5 16.1 2.3 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Drf_FH3 PF06367.16 PXF43709.1 - 8.1 6.0 10.2 6.1 6.4 1.0 2.1 1 1 1 2 2 2 0 Diaphanous FH3 Domain Pkinase PF00069.25 PXF43710.1 - 6.6e-18 65.0 0.0 6.8e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43710.1 - 3.4e-05 23.3 0.0 3.6e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.29 PXF43711.1 - 8.7e-50 168.9 0.0 2e-49 167.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43711.1 - 3.9e-28 98.0 0.0 1.2e-27 96.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF43711.1 - 0.0035 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mre11_DNA_bind PF04152.14 PXF43712.1 - 1.5e-28 100.2 0.0 4.1e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PXF43712.1 - 5.8e-06 27.0 0.2 1.1e-05 26.0 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MatP PF06303.12 PXF43712.1 - 0.05 14.2 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 MatP N-terminal domain Lactamase_B_4 PF13691.6 PXF43713.1 - 2.5e-11 43.1 0.0 6.4e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 PXF43713.1 - 1.5e-06 27.9 0.0 0.00011 21.8 0.1 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF43713.1 - 3.6e-05 23.9 0.0 0.00012 22.1 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CysG_dimeriser PF10414.9 PXF43714.1 - 0.024 14.3 0.0 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region F-box_4 PF15966.5 PXF43714.1 - 0.091 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 PXF43714.1 - 0.13 12.1 0.1 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 F-box-like HORMA PF02301.18 PXF43715.1 - 1.7e-19 70.3 0.1 2.2e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 PXF43715.1 - 0.05 13.4 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Peptidase_M27 PF01742.17 PXF43715.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Uso1_p115_head PF04869.14 PXF43716.1 - 7.6e-15 54.8 0.0 2.2e-13 50.0 0.0 3.5 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 PXF43716.1 - 0.00015 22.1 3.7 0.00015 22.1 3.7 20.0 1 1 18 20 20 20 4 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 PXF43716.1 - 0.0058 16.8 12.3 0.0058 16.8 12.3 18.5 2 2 13 18 18 18 1 Tropomyosin like HEAT PF02985.22 PXF43716.1 - 0.052 13.8 2.6 0.91 10.0 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat Actin PF00022.19 PXF43717.1 - 4.5e-83 279.1 0.1 1.8e-82 277.1 0.1 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PXF43717.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Glutaredoxin PF00462.24 PXF43718.1 - 2.8e-13 49.9 0.0 5.5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin zf-LYAR PF08790.11 PXF43719.1 - 3.5e-14 52.4 2.3 3.5e-14 52.4 2.3 3.0 4 0 0 4 4 4 2 LYAR-type C2HC zinc finger zf-met PF12874.7 PXF43719.1 - 0.0014 18.9 6.2 0.0044 17.4 2.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DM PF00751.18 PXF43719.1 - 0.0051 16.7 1.5 0.015 15.2 1.5 1.8 1 0 0 1 1 1 1 DM DNA binding domain zf-TRAF PF02176.18 PXF43719.1 - 0.032 14.9 1.6 0.083 13.6 1.6 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 PXF43719.1 - 0.042 14.1 1.6 0.042 14.1 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.6 PXF43719.1 - 0.13 12.2 2.2 10 6.1 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 PXF43719.1 - 0.19 12.7 4.1 10 7.3 0.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PXF43719.1 - 1.5 9.2 7.6 4.1 7.8 0.8 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PCI PF01399.27 PXF43720.1 - 4e-15 56.2 0.0 1.6e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain Laminin_II PF06009.12 PXF43721.1 - 0.0087 16.1 4.4 0.021 14.8 0.1 2.3 2 1 0 2 2 2 1 Laminin Domain II DUF948 PF06103.11 PXF43721.1 - 0.3 11.4 2.4 2 8.7 0.6 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 PXF43722.1 - 1.9e-60 204.5 0.0 2.3e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43722.1 - 8.7e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43722.1 - 1.1e-09 38.1 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PXF43722.1 - 0.039 12.7 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 PXF43722.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UQ_con PF00179.26 PXF43723.1 - 1.9e-18 66.5 0.0 3.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PXF43723.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Apt1 PF10351.9 PXF43723.1 - 0.7 8.7 3.3 0.83 8.4 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L6e PF01159.19 PXF43724.1 - 3.5e-34 117.7 0.7 5.1e-34 117.1 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosom_S12_S23 PF00164.25 PXF43725.1 - 1.2e-49 166.7 0.2 1.5e-49 166.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Alginate_lyase PF05426.12 PXF43727.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alginate lyase CHAT PF12770.7 PXF43729.1 - 1.2e-23 84.0 0.1 1.7e-19 70.3 0.1 2.0 2 0 0 2 2 2 2 CHAT domain Peptidase_C50 PF03568.17 PXF43729.1 - 0.029 13.5 0.4 0.029 13.5 0.4 1.4 2 0 0 2 2 2 0 Peptidase family C50 TPR_1 PF00515.28 PXF43730.1 - 1.5e-05 24.6 0.5 0.051 13.4 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF43730.1 - 0.0064 16.5 0.1 0.75 10.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF43730.1 - 0.035 14.4 0.3 3.6 7.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF43730.1 - 0.041 14.1 0.7 0.58 10.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF43730.1 - 0.043 13.9 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 PXF43730.1 - 0.046 14.4 0.0 0.24 12.1 0.0 2.3 2 0 0 2 2 2 0 Sel1 repeat MIT PF04212.18 PXF43730.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 PXF43731.1 - 7.3e-15 54.1 0.2 0.063 13.1 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat MIT PF04212.18 PXF43731.1 - 1.7e-10 40.8 0.1 0.32 11.1 0.0 4.8 5 0 0 5 5 5 3 MIT (microtubule interacting and transport) domain SNAP PF14938.6 PXF43731.1 - 2e-10 40.6 1.9 3.3e-05 23.5 0.7 3.1 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 PXF43731.1 - 1.2e-09 37.5 0.0 1.5 9.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF43731.1 - 5e-09 36.3 0.1 0.73 10.2 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF43731.1 - 5.2e-09 35.5 0.2 1.3 9.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF43731.1 - 2.7e-07 30.3 4.9 0.62 10.4 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF43731.1 - 1.5e-06 27.8 2.6 1.1 9.1 0.1 4.7 5 0 0 5 5 5 3 TPR repeat SGTA_dimer PF16546.5 PXF43731.1 - 2.8e-05 23.8 0.1 0.84 9.5 0.1 3.8 4 0 0 4 4 4 1 Homodimerisation domain of SGTA MiaE_2 PF13794.6 PXF43731.1 - 0.00022 21.0 0.4 0.094 12.4 0.1 2.8 2 1 1 3 3 3 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Sel1 PF08238.12 PXF43731.1 - 0.00028 21.5 0.0 19 6.1 0.0 4.2 4 0 0 4 4 4 0 Sel1 repeat UPF0253 PF06786.12 PXF43731.1 - 0.0014 18.8 0.2 0.28 11.5 0.0 3.7 4 1 1 5 5 5 1 Uncharacterised protein family (UPF0253) TPR_10 PF13374.6 PXF43731.1 - 0.0034 17.2 5.5 3.5 7.6 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 PXF43731.1 - 0.0035 17.5 2.1 0.29 11.4 0.1 3.7 3 1 1 4 4 4 1 MIT domain of nuclear receptor-binding factor 2 Dak2 PF02734.17 PXF43731.1 - 0.0043 17.0 1.0 0.19 11.6 0.0 3.4 2 2 2 4 4 4 1 DAK2 domain 14-3-3 PF00244.20 PXF43731.1 - 0.0073 15.8 0.1 0.81 9.2 0.0 2.5 2 1 0 2 2 2 1 14-3-3 protein Ig_6 PF18452.1 PXF43731.1 - 0.015 14.8 3.4 9.3 5.9 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin domain Imm5 PF14423.6 PXF43731.1 - 0.042 14.1 1.3 3 8.0 0.3 3.0 2 1 0 2 2 2 0 Immunity protein Imm5 Vta1_C PF18097.1 PXF43731.1 - 0.053 13.2 0.1 2.1 8.1 0.0 3.5 5 0 0 5 5 5 0 Vta1 C-terminal domain MFMR PF07777.11 PXF43731.1 - 0.096 13.2 1.0 15 6.2 0.0 3.5 3 1 1 4 4 4 0 G-box binding protein MFMR MIB_HERC2 PF06701.13 PXF43731.1 - 0.36 11.1 2.1 23 5.3 0.4 3.6 2 2 1 3 3 3 0 Mib_herc2 DUF4145 PF13643.6 PXF43731.1 - 0.36 11.0 2.9 15 5.8 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4145) DUF982 PF06169.12 PXF43731.1 - 2 8.5 5.4 12 6.1 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF982) LZ3wCH PF18517.1 PXF43731.1 - 2.2 8.4 6.2 5.4 7.2 1.1 3.2 3 0 0 3 3 3 0 Leucine zipper with capping helix domain YqaJ PF09588.10 PXF43732.1 - 5.4e-07 29.9 0.1 1.7e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain PAS_8 PF13188.7 PXF43732.1 - 0.008 16.2 0.2 0.17 12.0 0.0 3.1 4 0 0 4 4 4 1 PAS domain DDE_Tnp_1_7 PF13843.6 PXF43732.1 - 0.011 15.1 0.1 0.21 10.9 0.0 2.5 3 0 0 3 3 3 0 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 PXF43732.1 - 0.054 14.3 3.6 0.17 12.7 3.6 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon AAA_16 PF13191.6 PXF43732.1 - 0.074 13.4 0.4 0.41 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain MatB PF16449.5 PXF43734.1 - 0.098 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Fimbrillin MatB zf-CCHC_2 PF13696.6 PXF43735.1 - 4.5e-07 29.6 1.3 9e-07 28.6 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PXF43735.1 - 9.9e-05 22.3 0.7 9.9e-05 22.3 0.7 1.8 2 0 0 2 2 2 1 Zinc knuckle DUF4542 PF15075.6 PXF43735.1 - 0.011 16.2 0.4 0.015 15.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) rve PF00665.26 PXF43736.1 - 0.029 14.5 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Zip PF02535.22 PXF43737.1 - 1.1e-28 100.4 28.3 1.5e-18 67.1 19.1 3.1 1 1 1 2 2 2 2 ZIP Zinc transporter PBP1_TM PF14812.6 PXF43737.1 - 0.11 12.8 0.3 0.11 12.8 0.3 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 PXF43737.1 - 5.6 7.3 8.1 0.78 10.0 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) efThoc1 PF11957.8 PXF43738.1 - 0.0079 14.9 0.1 0.0084 14.8 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Imm39 PF15568.6 PXF43739.1 - 0.044 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 RVT_2 PF07727.14 PXF43740.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANAPC4_WD40 PF12894.7 PXF43741.1 - 1.7e-08 34.6 0.0 1.7 9.0 0.0 4.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF43741.1 - 2e-06 28.4 2.0 9.6e-05 23.1 0.6 3.9 3 1 1 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.9 PXF43741.1 - 0.0005 19.9 0.1 0.0015 18.4 0.1 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40_like PF17005.5 PXF43741.1 - 0.023 14.0 0.1 0.35 10.2 0.1 2.3 3 0 0 3 3 3 0 WD40-like domain Gln-synt_C-ter PF18318.1 PXF43745.1 - 0.038 13.9 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain UPF0257 PF06788.13 PXF43745.1 - 0.083 12.7 0.7 0.091 12.6 0.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) Methyltransf_23 PF13489.6 PXF43751.1 - 1.5e-18 67.2 0.0 5.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PXF43751.1 - 2.2e-15 57.1 0.0 1.6e-06 28.8 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PXF43751.1 - 3.4e-12 47.0 0.0 9.7e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PXF43751.1 - 6.8e-12 45.4 0.0 5.9e-06 26.1 0.0 3.4 2 2 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 PXF43751.1 - 3.1e-11 43.8 0.0 0.00045 20.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 PXF43751.1 - 1.5e-06 27.8 0.0 0.0037 16.6 0.0 2.5 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 PXF43751.1 - 2.5e-05 23.9 0.0 0.0031 17.1 0.0 3.0 3 0 0 3 3 3 1 AdoMet dependent proline di-methyltransferase Methyltransf_28 PF02636.17 PXF43751.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Mononeg_mRNAcap PF14318.6 PXF43751.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V TusA PF01206.17 PXF43752.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Sulfurtransferase TusA TFIIA PF03153.13 PXF43752.1 - 8.7 6.2 17.1 12 5.8 17.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_3 PF13302.7 PXF43753.1 - 0.006 17.3 0.1 0.012 16.3 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain UDPGT PF00201.18 PXF43753.1 - 0.039 12.7 0.1 0.055 12.3 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Acetyltransf_1 PF00583.25 PXF43753.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HAP2-GCS1 PF10699.9 PXF43753.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Male gamete fusion factor Alk_phosphatase PF00245.20 PXF43755.1 - 4.8e-78 263.0 2.0 3.7e-70 237.0 1.0 2.1 2 0 0 2 2 2 2 Alkaline phosphatase Phosphodiest PF01663.22 PXF43755.1 - 5.3e-05 23.0 0.2 8e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 PXF43755.1 - 0.00018 21.0 0.7 0.00034 20.0 0.3 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 PXF43755.1 - 0.027 13.9 0.4 0.17 11.2 0.1 2.0 1 1 0 2 2 2 0 Sulfatase Pkinase PF00069.25 PXF43756.1 - 7.3e-74 248.5 0.0 9.5e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43756.1 - 4.2e-39 134.4 0.0 5.8e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43756.1 - 5.8e-06 25.8 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AdenylateSensor PF16579.5 PXF43756.1 - 7.9e-05 23.1 0.0 0.00018 21.9 0.0 1.6 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 PXF43756.1 - 0.00068 19.4 0.7 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Haspin_kinase PF12330.8 PXF43756.1 - 0.0029 16.6 0.1 0.0043 16.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF43756.1 - 0.054 12.9 0.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_33 PF13592.6 PXF43756.1 - 0.068 12.8 0.2 0.2 11.3 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix PheRS_DBD3 PF18553.1 PXF43756.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 3 YukC PF10140.9 PXF43756.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC CENP-T_C PF15511.6 PXF43757.1 - 1.3e-08 34.9 0.1 1.6e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PXF43757.1 - 0.001 19.4 0.1 0.0017 18.7 0.1 1.5 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 PXF43757.1 - 0.0012 19.2 0.2 0.0015 18.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF43757.1 - 0.002 18.4 0.1 0.003 17.8 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 PXF43757.1 - 0.0033 17.5 0.2 0.0046 17.1 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 PXF43757.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PXF43757.1 - 0.082 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 PXF43758.1 - 1.2e-51 174.5 1.6 1.3e-51 174.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PXF43758.1 - 0.00012 22.1 0.5 0.00019 21.5 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PXF43758.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 PXF43758.1 - 0.00039 21.0 1.0 0.00046 20.8 1.0 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 PXF43758.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PXF43758.1 - 0.086 12.9 0.1 0.17 12.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Met_10 PF02475.16 PXF43759.1 - 1.9e-59 200.8 0.0 4e-59 199.7 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_15 PF09445.10 PXF43759.1 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 PXF43759.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 PXF43759.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 PXF43759.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PXF43759.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 PXF43759.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MethyltransfD12 PF02086.15 PXF43759.1 - 0.056 13.1 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 PXF43759.1 - 0.15 12.8 0.0 0.47 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF2695 PF10905.8 PXF43759.1 - 0.26 11.6 0.9 18 5.6 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2695) ALG3 PF05208.13 PXF43760.1 - 1e-124 416.6 13.9 1.3e-124 416.3 13.9 1.1 1 0 0 1 1 1 1 ALG3 protein SOUL PF04832.12 PXF43761.1 - 0.00015 22.0 0.0 0.004 17.4 0.0 2.6 3 0 0 3 3 3 1 SOUL heme-binding protein UCH PF00443.29 PXF43762.1 - 2.2e-48 165.0 0.0 3.6e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF43762.1 - 1.1e-23 84.3 0.0 2.7e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PXF43762.1 - 0.00035 20.1 1.1 4.1 6.8 0.4 3.7 4 0 0 4 4 4 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase HalX PF08663.10 PXF43762.1 - 0.05 13.9 0.8 0.1 13.0 0.8 1.5 1 0 0 1 1 1 0 HalX domain MalM PF07148.12 PXF43762.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) GMC_oxred_N PF00732.19 PXF43763.1 - 1.2e-78 264.6 0.0 1.7e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF43763.1 - 1.5e-33 116.3 0.1 2.5e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 PXF43763.1 - 1.5e-06 27.6 0.4 0.00053 19.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 PXF43763.1 - 2.9e-06 27.1 0.3 0.00049 19.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF43763.1 - 3.4e-05 23.2 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF43763.1 - 5.9e-05 22.3 0.1 9.9e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 PXF43763.1 - 6.3e-05 23.1 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PXF43763.1 - 0.00019 20.8 0.0 0.05 12.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF43763.1 - 0.0097 14.6 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 PXF43763.1 - 0.094 12.7 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2358 PF10184.9 PXF43764.1 - 1.9e-11 44.2 0.0 3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 PXF43764.1 - 0.016 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain TFIIE_alpha PF02002.17 PXF43765.1 - 6.3e-09 35.6 1.3 1.9e-08 34.1 1.3 1.9 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 PXF43765.1 - 0.0014 18.6 0.7 0.012 15.6 0.2 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_micro PF17007.5 PXF43765.1 - 0.014 14.2 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 HTH-like TFIIE-A_C PF11521.8 PXF43765.1 - 0.017 15.4 20.9 0.017 15.4 20.9 3.1 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha FeoC PF09012.10 PXF43765.1 - 0.023 14.8 0.6 0.11 12.6 0.2 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF2576 PF10845.8 PXF43765.1 - 0.4 10.3 1.7 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) HA PF03457.14 PXF43766.1 - 1.5e-51 172.6 14.6 5.4e-17 61.9 0.1 3.3 3 0 0 3 3 3 3 Helicase associated domain MgpC PF05220.12 PXF43766.1 - 0.0099 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 1 MgpC protein precursor ABC1 PF03109.16 PXF43767.1 - 8.6e-34 116.3 0.0 2.7e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 PXF43767.1 - 0.00052 19.5 0.3 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 PXF43767.1 - 0.0089 16.0 0.3 0.0089 16.0 0.3 2.9 3 2 0 3 3 3 1 Phosphotransferase enzyme family CnrY PF17524.2 PXF43767.1 - 0.29 11.4 2.9 20 5.5 0.9 2.8 2 0 0 2 2 2 0 Anti-sigma factor CnrY Sod_Fe_C PF02777.18 PXF43768.1 - 4.6e-40 135.9 0.6 7.5e-40 135.2 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PXF43768.1 - 1.5e-26 92.6 0.3 2.8e-26 91.8 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.25 PXF43769.1 - 1.1e-21 77.4 0.0 1.6e-18 67.0 0.0 3.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43769.1 - 5.7e-18 65.1 0.0 2.1e-08 33.7 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PXF43769.1 - 0.005 16.8 0.4 0.005 16.8 0.4 3.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF43769.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ddrB-ParB PF18763.1 PXF43769.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain Spore_YtrH PF14034.6 PXF43769.1 - 0.059 13.5 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Sporulation protein YtrH DAG1 PF05454.11 PXF43769.1 - 0.9 8.9 5.9 1.5 8.1 5.9 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) AMPK1_CBM PF16561.5 PXF43770.1 - 0.093 13.0 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase 53-BP1_Tudor PF09038.10 PXF43771.1 - 0.12 12.4 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor An_peroxidase PF03098.15 PXF43773.1 - 5.1e-107 358.6 0.1 1.3e-100 337.5 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase SnoaL_2 PF12680.7 PXF43774.1 - 3.1e-16 59.9 2.0 2.6e-08 34.4 0.1 2.2 2 0 0 2 2 2 2 SnoaL-like domain SnoaL PF07366.12 PXF43774.1 - 4.9e-12 45.7 4.3 0.00025 20.9 0.3 3.9 2 2 0 2 2 2 2 SnoaL-like polyketide cyclase LEH PF07858.12 PXF43774.1 - 0.00063 19.8 0.1 0.59 10.3 0.0 2.3 2 0 0 2 2 2 2 Limonene-1,2-epoxide hydrolase catalytic domain Ral PF11058.8 PXF43774.1 - 0.0069 15.9 0.5 18 5.0 0.0 3.5 3 0 0 3 3 3 2 Antirestriction protein Ral zf-C2H2_4 PF13894.6 PXF43775.1 - 1e-15 57.0 31.4 0.0001 22.8 0.3 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF43775.1 - 1.4e-15 56.8 38.9 0.00018 21.8 3.1 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF43775.1 - 4.2e-09 36.4 29.3 7.5e-05 23.0 0.4 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PXF43775.1 - 6.3e-09 35.9 13.5 0.0072 16.6 1.8 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PXF43775.1 - 1.8e-07 31.3 15.5 3e-05 24.2 0.7 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PXF43775.1 - 1.3e-06 28.2 24.6 0.06 13.4 0.1 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 PXF43775.1 - 4.5e-06 26.9 11.7 0.0098 16.3 1.3 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.15 PXF43775.1 - 2.5e-05 24.2 19.3 0.0019 18.2 4.0 4.5 4 1 1 5 5 5 1 BED zinc finger Zn-ribbon_8 PF09723.10 PXF43775.1 - 0.00022 21.3 15.2 0.92 9.7 0.2 4.4 4 0 0 4 4 4 2 Zinc ribbon domain DUF2256 PF10013.9 PXF43775.1 - 0.0048 17.0 8.6 0.56 10.4 0.0 4.1 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2256) TF_Zn_Ribbon PF08271.12 PXF43775.1 - 0.0066 15.9 8.8 0.22 11.1 0.3 3.8 3 1 0 3 3 3 1 TFIIB zinc-binding zf-C2H2_11 PF16622.5 PXF43775.1 - 0.0074 16.0 0.4 0.0074 16.0 0.4 3.5 4 0 0 4 4 3 1 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 PXF43775.1 - 0.0085 15.8 8.1 0.039 13.7 1.2 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 PXF43775.1 - 0.0091 15.8 4.5 0.26 11.2 0.0 3.3 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 PXF43775.1 - 0.022 14.7 22.5 0.56 10.2 0.1 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 PXF43775.1 - 0.039 14.3 21.4 2.4 8.6 0.5 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 PXF43775.1 - 0.056 14.2 16.6 2.3 9.0 4.4 3.2 1 1 0 2 2 2 0 zinc-ribbon family C1_4 PF07975.12 PXF43775.1 - 0.056 13.7 20.8 0.5 10.6 0.4 4.4 1 1 3 4 4 4 0 TFIIH C1-like domain Trm112p PF03966.16 PXF43775.1 - 0.1 13.2 8.6 13 6.5 0.2 3.7 2 1 1 3 3 3 0 Trm112p-like protein DZR PF12773.7 PXF43775.1 - 0.14 12.2 15.3 2.3e+03 -1.3 15.3 3.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4379 PF14311.6 PXF43775.1 - 0.14 12.5 11.1 4.4 7.7 1.4 3.5 3 0 0 3 3 3 0 Probable Zinc-ribbon domain FYDLN_acid PF09538.10 PXF43775.1 - 0.16 12.6 1.7 11 6.7 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) CpXC PF14353.6 PXF43775.1 - 0.3 11.1 14.7 2.3 8.3 0.2 4.6 1 1 3 4 4 4 0 CpXC protein A2L_zn_ribbon PF08792.10 PXF43775.1 - 0.32 10.8 10.6 9 6.1 0.1 4.8 5 0 0 5 5 5 0 A2L zinc ribbon domain Jas PF16135.5 PXF43775.1 - 0.45 10.7 11.0 0.36 11.0 7.5 2.6 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling zf-C2H2_3rep PF18868.1 PXF43775.1 - 0.48 11.1 12.4 0.39 11.4 7.6 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Rpr2 PF04032.16 PXF43775.1 - 0.81 10.0 16.6 1.4 9.2 4.7 3.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_Hakai PF18408.1 PXF43775.1 - 1.1 9.1 0.1 1.1 9.1 0.1 3.7 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain HypA PF01155.19 PXF43775.1 - 1.1 9.3 14.6 2.2 8.3 1.3 3.2 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 PXF43775.1 - 1.1 9.3 20.6 8.7 6.4 2.4 3.9 1 1 2 4 4 4 0 zinc-ribbons Rubredoxin PF00301.20 PXF43775.1 - 1.4 9.0 11.9 32 4.7 0.1 5.0 5 0 0 5 5 5 0 Rubredoxin Zn_Tnp_IS1595 PF12760.7 PXF43775.1 - 1.8 8.6 25.8 2 8.5 0.5 4.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.6 PXF43775.1 - 3.1 7.8 12.2 5.7 6.9 0.1 4.3 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 PXF43775.1 - 5.4 7.4 21.8 5.7 7.3 3.2 5.0 2 1 2 4 4 4 0 C1 domain GAGA PF09237.11 PXF43775.1 - 7.8 6.4 9.2 0.73 9.7 1.8 2.9 2 1 1 3 3 3 0 GAGA factor ADK_lid PF05191.14 PXF43775.1 - 7.9 6.6 19.5 1.9 8.5 1.8 4.5 4 1 1 5 5 5 0 Adenylate kinase, active site lid zf-C2H2_8 PF15909.5 PXF43775.1 - 8.1 6.8 14.0 16 5.9 4.6 3.3 1 1 3 4 4 4 0 C2H2-type zinc ribbon UCH PF00443.29 PXF43776.1 - 1.8e-43 148.9 0.0 2.3e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF43776.1 - 2.4e-12 47.1 0.0 7.9e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PXF43776.1 - 0.094 12.2 0.8 0.73 9.3 0.5 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PrmA PF06325.13 PXF43777.1 - 0.011 15.1 0.5 0.018 14.5 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) F420_oxidored PF03807.17 PXF43777.1 - 0.13 12.9 1.2 0.65 10.6 0.3 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FtsK_SpoIIIE PF01580.18 PXF43779.1 - 0.0058 16.0 0.1 0.0066 15.8 0.1 1.0 1 0 0 1 1 1 1 FtsK/SpoIIIE family DHquinase_I PF01487.15 PXF43779.1 - 0.053 13.8 0.8 0.056 13.7 0.8 1.0 1 0 0 1 1 1 0 Type I 3-dehydroquinase Prefoldin_3 PF13758.6 PXF43780.1 - 0.0019 18.2 2.8 0.04 14.0 0.5 2.2 1 1 1 2 2 2 1 Prefoldin subunit Prominin PF05478.11 PXF43780.1 - 0.059 11.3 0.3 0.066 11.2 0.3 1.0 1 0 0 1 1 1 0 Prominin CK2S PF15011.6 PXF43780.1 - 0.068 13.1 1.0 0.08 12.8 1.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate CREPT PF16566.5 PXF43780.1 - 0.072 13.3 1.2 0.7 10.1 0.2 2.1 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour RIH_assoc PF08454.11 PXF43780.1 - 0.075 12.9 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 RyR and IP3R Homology associated RecG_N PF17190.4 PXF43780.1 - 0.21 12.3 1.5 2.3 9.0 0.8 2.6 1 1 1 2 2 2 0 RecG N-terminal helical domain FH2 PF02181.23 PXF43781.1 - 8.5e-15 54.7 0.3 9.4e-15 54.6 0.3 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain 2OG-FeII_Oxy_2 PF13532.6 PXF43783.1 - 7.6e-10 39.3 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-E2_ATPase PF00122.20 PXF43784.1 - 2e-39 135.0 1.2 8.3e-39 133.0 0.2 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PXF43784.1 - 7.6e-30 104.8 1.7 8.5e-29 101.3 1.3 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF43784.1 - 0.00011 22.0 0.3 0.14 11.9 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_hydro_31 PF01055.26 PXF43785.1 - 2.3e-20 73.2 0.1 3e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 PXF43785.1 - 3.3e-09 36.9 0.1 1.2e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 PXF43786.1 - 4.1e-92 309.7 3.5 5.4e-92 309.3 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 PXF43786.1 - 2.3e-18 66.3 0.9 8e-18 64.5 0.0 2.4 3 0 0 3 3 3 1 Galactose mutarotase-like Pheromone PF08015.11 PXF43786.1 - 0.31 12.1 2.6 1 10.5 2.6 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone SnoaL_3 PF13474.6 PXF43787.1 - 7.3e-11 42.4 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain UVR PF02151.19 PXF43787.1 - 0.0023 17.6 0.4 0.0031 17.2 0.4 1.2 1 0 0 1 1 1 1 UvrB/uvrC motif PSII_BNR PF14870.6 PXF43787.1 - 0.069 12.4 0.0 2.1 7.5 0.0 2.0 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Prenyltransf PF01255.19 PXF43788.1 - 1.2e-63 214.6 0.0 1.4e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Serendipity_A PF05482.12 PXF43788.1 - 0.088 11.4 0.0 1.8 7.1 0.0 2.0 2 0 0 2 2 2 0 Serendipity locus alpha protein (SRY-A) CaATP_NAI PF12515.8 PXF43788.1 - 0.16 11.6 1.5 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Telomerase_RBD PF12009.8 PXF43789.1 - 2.3e-27 95.7 0.2 2.3e-27 95.7 0.2 2.7 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 PXF43789.1 - 1.3e-08 34.6 0.0 3.8e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) PAP_assoc PF03828.19 PXF43790.1 - 2.4e-09 37.2 1.1 3.5e-05 23.9 0.2 2.6 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PXF43790.1 - 2e-08 34.4 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.17 PXF43790.1 - 0.0042 16.1 0.0 0.0077 15.2 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Nrap_D2 PF17403.2 PXF43790.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain API5 PF05918.11 PXF43790.1 - 4.8 5.9 5.9 3.1 6.5 4.1 1.5 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) RSN1_7TM PF02714.15 PXF43791.1 - 1e-51 175.9 15.6 2e-51 175.0 15.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PXF43791.1 - 2.9e-24 85.6 0.4 2.9e-24 85.6 0.4 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PXF43791.1 - 2.7e-11 44.0 0.0 1e-10 42.1 0.0 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Hint PF01079.20 PXF43792.1 - 2e-32 112.4 0.0 3.6e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 PXF43792.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Pretoxin HINT domain SGL PF08450.12 PXF43792.1 - 0.024 14.2 0.0 3.7 7.1 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region AIM24 PF01987.17 PXF43792.1 - 0.11 12.3 0.8 5.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial biogenesis AIM24 Archease PF01951.16 PXF43793.1 - 1.1e-40 139.0 0.1 1.4e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) USP7_C2 PF14533.6 PXF43794.1 - 0.049 13.3 0.1 0.075 12.7 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal DEAD PF00270.29 PXF43795.1 - 2.4e-27 95.8 0.4 2.8e-26 92.4 0.4 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43795.1 - 2.4e-19 69.7 0.0 8.6e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF43795.1 - 7.2e-09 35.9 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 PXF43795.1 - 0.049 12.9 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.6 PXF43795.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 PXF43795.1 - 0.15 12.3 2.1 5.1 7.4 1.2 2.8 2 1 0 2 2 2 0 AAA domain S4 PF01479.25 PXF43796.1 - 3.5e-09 36.2 2.0 1.4e-08 34.3 0.8 2.5 1 1 1 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 PXF43796.1 - 3.5e-07 30.4 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase MraY_sig1 PF10555.9 PXF43797.1 - 0.025 14.1 0.7 0.063 12.8 0.7 1.7 1 0 0 1 1 1 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 NatB_MDM20 PF09797.9 PXF43798.1 - 6.8e-58 196.4 0.0 1.4e-57 195.4 0.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 PXF43798.1 - 4.4e-08 33.5 0.8 0.0012 19.3 0.9 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat SPOB_a PF14689.6 PXF43798.1 - 0.052 13.3 1.5 0.28 10.9 0.1 2.5 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain GSDH PF07995.11 PXF43799.1 - 1.6e-23 83.5 0.0 2.5e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PQQ_3 PF13570.6 PXF43799.1 - 0.044 14.3 0.1 2.4 8.8 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain NHL PF01436.21 PXF43799.1 - 0.083 13.0 0.6 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 NHL repeat Ion_trans PF00520.31 PXF43801.1 - 8.3e-37 126.7 41.7 1.1e-25 90.3 17.1 2.3 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 PXF43801.1 - 1.4e-06 28.0 0.6 3.7e-06 26.7 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 PXF43801.1 - 4.8e-05 23.7 0.5 0.00013 22.4 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PXF43801.1 - 0.0026 17.2 0.1 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PXF43801.1 - 0.0088 15.9 0.5 0.035 14.0 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain Ank_2 PF12796.7 PXF43802.1 - 9.8e-08 32.5 0.2 6.8e-05 23.4 0.0 3.5 2 1 3 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF43802.1 - 1.6e-07 31.7 1.7 0.0068 17.0 0.0 4.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF43802.1 - 2.3e-07 30.6 1.3 0.24 12.1 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PXF43802.1 - 4.6e-07 30.0 0.3 0.036 14.4 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) F-box-like PF12937.7 PXF43802.1 - 4.7e-07 29.6 0.1 5.2e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 F-box-like Ank PF00023.30 PXF43802.1 - 9e-05 22.8 0.9 0.6 10.7 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeat F-box PF00646.33 PXF43802.1 - 0.0016 18.2 0.7 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 F-box domain DnaJ_CXXCXGXG PF00684.19 PXF43803.1 - 0.014 15.8 14.3 0.22 11.9 10.8 2.8 2 1 1 3 3 3 0 DnaJ central domain Transp_Tc5_C PF04236.15 PXF43803.1 - 0.19 12.1 7.2 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Sulfotransfer_2 PF03567.14 PXF43804.1 - 1.6e-05 24.9 0.1 0.00021 21.3 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Cpn60_TCP1 PF00118.24 PXF43806.1 - 5.1e-159 530.0 2.0 5.7e-159 529.9 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD PF00270.29 PXF43807.1 - 8.1e-18 64.8 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43807.1 - 2.9e-15 56.6 0.0 1.5e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PXF43807.1 - 1e-11 45.4 0.8 3.5e-11 43.7 0.8 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 PXF43807.1 - 8e-05 22.4 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain DUF812 PF05667.11 PXF43807.1 - 0.86 8.4 6.2 1.5 7.6 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CCT PF06203.14 PXF43808.1 - 9.8e-11 41.5 17.3 1.8e-10 40.6 17.3 1.4 1 0 0 1 1 1 1 CCT motif Josephin PF02099.17 PXF43811.1 - 7.4e-24 84.7 0.0 1.8e-23 83.5 0.0 1.5 1 1 0 1 1 1 1 Josephin Pox_P35 PF03213.14 PXF43811.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein Na_H_Exchanger PF00999.21 PXF43812.1 - 3.4e-46 157.8 45.8 4.2e-46 157.5 45.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.8 PXF43812.1 - 0.3 11.2 2.1 1.3 9.1 2.1 2.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF962 PF06127.11 PXF43812.1 - 0.51 10.5 3.9 0.88 9.7 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF2627 PF11118.8 PXF43812.1 - 6.1 7.5 7.3 1.7 9.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF3754 PF12576.8 PXF43812.1 - 6.1 6.8 6.1 4.2 7.3 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) LapA_dom PF06305.11 PXF43812.1 - 7.5 6.4 8.9 19 5.2 0.1 4.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Sigma70_r4 PF04545.16 PXF43815.1 - 3.5e-06 26.4 0.0 7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 PXF43815.1 - 2.6e-05 23.9 0.4 6.6e-05 22.6 0.4 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 HTH_10 PF04967.12 PXF43815.1 - 0.076 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain POT1PC PF16686.5 PXF43816.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein FBPase PF00316.20 PXF43817.1 - 3.7e-38 130.9 0.1 5e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain GGACT PF06094.12 PXF43818.1 - 3.2e-20 73.0 0.1 4.1e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like RIO1 PF01163.22 PXF43819.1 - 3e-42 144.4 0.0 6.5e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 PXF43819.1 - 3.1e-33 113.8 0.2 3.1e-33 113.8 0.2 2.3 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.23 PXF43819.1 - 2.6e-08 34.1 7.2 0.00034 20.6 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 PXF43819.1 - 1.2e-05 24.8 0.4 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 PXF43819.1 - 1.7e-05 24.3 0.6 0.00075 18.9 0.6 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 PXF43819.1 - 3.5e-05 23.5 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 PXF43819.1 - 0.004 16.5 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 PXF43819.1 - 0.01 15.5 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 PXF43819.1 - 0.029 13.7 0.6 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like CDC45 PF02724.14 PXF43819.1 - 3.6 5.8 10.0 4.3 5.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PCRF PF03462.18 PXF43820.1 - 1.6e-69 233.7 0.6 2.2e-69 233.2 0.1 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 PXF43820.1 - 4.6e-39 132.9 1.1 9.2e-39 132.0 1.1 1.5 1 0 0 1 1 1 1 RF-1 domain VSG_B PF13206.6 PXF43820.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain ABC_tran_CTD PF16326.5 PXF43820.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain MerR-DNA-bind PF09278.11 PXF43820.1 - 1.1 9.8 4.9 2.5 8.7 1.0 2.5 2 0 0 2 2 2 0 MerR, DNA binding PPTA PF01239.22 PXF43821.1 - 5.7e-36 121.2 9.9 1.4e-10 40.6 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.6 PXF43821.1 - 0.0043 17.5 1.0 0.0043 17.5 1.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4219 PF13961.6 PXF43821.1 - 0.014 15.0 5.3 4.2 7.1 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4219) TPR_17 PF13431.6 PXF43821.1 - 0.086 13.3 2.5 8.4 7.0 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AcylCoA_dehyd_C PF12186.8 PXF43822.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase C terminal CCDC106 PF15794.5 PXF43822.1 - 9.9 5.8 9.9 18 4.9 9.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 F-box PF00646.33 PXF43823.1 - 9.7e-07 28.5 0.3 2e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF43823.1 - 3.9e-06 26.7 0.5 3.9e-06 26.7 0.5 2.2 2 0 0 2 2 2 1 F-box-like MAT1 PF06391.13 PXF43825.1 - 5e-26 91.8 20.7 7.6e-26 91.2 20.7 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 GAGA_bind PF06217.12 PXF43825.1 - 0.41 10.9 6.7 0.48 10.7 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RHD3 PF05879.12 PXF43826.1 - 2.4e-64 217.8 0.0 1.4e-63 215.3 0.0 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 PXF43826.1 - 9.2e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF43826.1 - 0.00025 21.1 0.2 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GBP PF02263.19 PXF43826.1 - 0.0003 20.1 0.0 0.00062 19.1 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 PXF43826.1 - 0.0036 17.6 2.0 0.0045 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PXF43826.1 - 0.0061 17.1 0.2 0.1 13.1 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_14 PF13173.6 PXF43826.1 - 0.0066 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF43826.1 - 0.01 16.2 0.3 0.046 14.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 PXF43826.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 PXF43826.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 PXF43826.1 - 0.037 13.9 0.1 0.25 11.2 0.0 2.3 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 PXF43826.1 - 0.043 14.3 4.5 0.18 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PXF43826.1 - 0.051 14.1 0.0 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ParG PF09274.10 PXF43826.1 - 0.13 12.4 0.6 30 4.8 0.0 3.6 4 0 0 4 4 3 0 ParG AAA_24 PF13479.6 PXF43826.1 - 0.16 11.7 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Atx10homo_assoc PF09759.9 PXF43827.1 - 2.1e-11 43.7 3.0 0.00047 20.1 0.0 4.9 3 1 1 5 5 5 3 Spinocerebellar ataxia type 10 protein domain Sel1 PF08238.12 PXF43827.1 - 2e-07 31.5 15.8 0.025 15.3 0.4 5.6 5 0 0 5 5 5 3 Sel1 repeat Arm PF00514.23 PXF43827.1 - 1.2e-05 25.2 0.1 4.5 7.4 0.0 5.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Bax1-I PF01027.20 PXF43828.1 - 0.0081 16.0 9.7 0.0095 15.8 9.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4267 PF14087.6 PXF43828.1 - 0.02 14.9 2.5 0.026 14.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Bromodomain PF00439.25 PXF43829.1 - 1.8e-15 56.8 0.4 9.1e-15 54.5 0.1 2.4 3 0 0 3 3 3 1 Bromodomain BET PF17035.5 PXF43829.1 - 1.9e-13 50.4 0.0 4.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DEK_C PF08766.11 PXF43829.1 - 0.023 14.6 0.1 0.086 12.8 0.1 2.0 1 0 0 1 1 1 0 DEK C terminal domain TipAS PF07739.13 PXF43829.1 - 0.088 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain zf-C2H2_4 PF13894.6 PXF43830.1 - 2.7e-14 52.7 20.2 0.00027 21.5 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF43830.1 - 5.1e-13 48.7 21.6 0.0019 18.6 1.1 5.2 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF43830.1 - 9.7e-11 41.6 15.8 0.00014 22.1 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 PXF43830.1 - 6.8e-10 39.0 4.4 0.33 11.4 0.2 4.8 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF43830.1 - 4.6e-07 29.9 4.7 0.21 11.9 0.3 4.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-trcl PF13451.6 PXF43830.1 - 0.00039 20.2 10.0 0.0024 17.7 1.5 3.4 3 0 0 3 3 3 1 Probable zinc-ribbon domain DZR PF12773.7 PXF43830.1 - 0.00048 20.1 5.8 0.048 13.7 5.8 2.5 1 1 0 1 1 1 1 Double zinc ribbon zf-C2H2_11 PF16622.5 PXF43830.1 - 0.00078 19.1 18.8 0.0008 19.1 0.0 5.0 6 0 0 6 6 4 1 zinc-finger C2H2-type zf-Di19 PF05605.12 PXF43830.1 - 0.0011 19.2 10.7 0.0055 17.0 1.8 3.4 1 1 2 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PXF43830.1 - 0.0018 18.3 10.6 1.3 9.2 0.2 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 PXF43830.1 - 0.0087 16.2 8.4 1.3 9.2 0.7 3.6 3 1 0 3 3 3 1 Zinc ribbon domain zf-C2H2_2 PF12756.7 PXF43830.1 - 0.012 15.9 14.7 0.54 10.6 1.2 4.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CpG_bind_C PF12269.8 PXF43830.1 - 0.024 14.5 8.1 0.043 13.6 4.0 2.3 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-ribbon_3 PF13248.6 PXF43830.1 - 0.046 13.1 6.6 0.86 9.1 0.2 2.9 3 0 0 3 3 2 0 zinc-ribbon domain ADK_lid PF05191.14 PXF43830.1 - 0.059 13.4 7.7 0.45 10.5 0.5 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_3rep PF18868.1 PXF43830.1 - 0.064 13.9 18.9 0.27 11.9 0.1 4.4 2 1 3 5 5 4 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_10 PF18414.1 PXF43830.1 - 0.08 12.5 0.0 1 9.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2HE PF16278.5 PXF43830.1 - 0.12 12.8 22.1 0.46 11.0 2.6 4.5 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 PXF43830.1 - 0.13 12.1 0.4 0.13 12.1 0.4 4.9 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 PXF43830.1 - 0.17 11.8 3.1 12 5.8 0.0 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) LIM PF00412.22 PXF43830.1 - 0.17 12.1 8.5 2.9 8.2 2.0 3.2 2 1 0 2 2 2 0 LIM domain Ta0938 PF11494.8 PXF43830.1 - 0.35 11.2 1.2 1.1 9.5 0.8 1.9 1 1 1 2 2 2 0 Ta0938 zinc_ribbon_2 PF13240.6 PXF43830.1 - 0.36 10.6 6.2 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 PXF43830.1 - 0.37 10.7 6.9 0.67 9.9 0.5 3.2 3 1 1 4 4 3 0 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.12 PXF43830.1 - 0.42 10.6 10.0 5.6 7.0 2.9 3.4 1 1 2 3 3 3 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 PXF43830.1 - 0.45 10.5 8.2 5.7 7.0 2.7 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF1644 PF07800.12 PXF43830.1 - 0.82 9.7 23.3 0.11 12.5 11.8 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1644) zinc_ribbon_10 PF10058.9 PXF43830.1 - 2.3 8.0 10.2 3.1 7.6 0.9 3.2 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-AN1 PF01428.16 PXF43830.1 - 3.3 8.0 8.1 27 5.0 0.1 3.9 4 0 0 4 4 4 0 AN1-like Zinc finger DUF1356 PF07092.12 PXF43830.1 - 3.9 6.7 4.6 5.1 6.3 2.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) zf-FPG_IleRS PF06827.14 PXF43830.1 - 4.3 7.3 7.0 11 6.0 0.2 3.5 3 1 0 3 3 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_4 PF13717.6 PXF43830.1 - 4.7 7.2 10.5 18 5.3 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain GFA PF04828.14 PXF43830.1 - 5.8 7.3 8.5 6.5 7.2 3.3 3.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf_C2H2_ZHX PF18387.1 PXF43830.1 - 7.3 6.3 9.3 4.2 7.1 0.1 3.6 3 1 1 4 4 3 0 Zinc-fingers and homeoboxes C2H2 finger domain GCS PF03074.16 PXF43831.1 - 2.4e-154 514.1 0.0 3e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF4703 PF15775.5 PXF43831.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) PET117 PF15786.5 PXF43832.1 - 9.1e-13 48.3 0.9 1e-12 48.1 0.9 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Phage_Gp23 PF10669.9 PXF43832.1 - 0.027 14.8 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CcmD PF04995.14 PXF43832.1 - 0.85 9.8 4.1 1.6 8.9 0.8 2.4 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) Complex1_30kDa PF00329.19 PXF43833.1 - 1.5e-40 138.6 0.1 2.5e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SMP_LBD PF17047.5 PXF43834.1 - 1.5e-23 83.2 0.1 2.2e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 PXF43834.1 - 9.5e-18 64.4 0.0 2.1e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain Pkinase PF00069.25 PXF43835.1 - 8.4e-79 264.6 0.0 9.8e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43835.1 - 2.3e-33 115.6 0.0 2.9e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF43835.1 - 6.9e-05 22.0 0.1 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PXF43835.1 - 0.037 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 PXF43835.1 - 0.083 11.9 0.1 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Vps8 PF12816.7 PXF43835.1 - 0.11 12.0 0.1 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 APH PF01636.23 PXF43835.1 - 0.24 11.3 1.3 1.3 8.9 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4477 PF14780.6 PXF43836.1 - 2.9e-09 36.8 3.0 2.5e-05 24.0 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) PAP_fibrillin PF04755.12 PXF43837.1 - 8.2e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin Use1 PF09753.9 PXF43838.1 - 0.22 11.2 13.2 0.44 10.2 12.0 1.9 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF2828 PF11443.8 PXF43838.1 - 0.87 7.6 8.5 1.2 7.2 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_11 PF13086.6 PXF43838.1 - 4.3 7.0 8.1 6.4 6.5 8.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2058 PF09831.9 PXF43838.1 - 6.9 6.8 15.5 10 6.2 15.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ABC_tran PF00005.27 PXF43840.1 - 4.3e-25 88.8 0.0 5.5e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF43840.1 - 2.3e-05 24.4 0.0 0.073 12.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PXF43840.1 - 0.00029 21.3 0.0 0.00039 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 PXF43840.1 - 0.00093 19.2 0.0 0.0024 17.8 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 PXF43840.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PXF43840.1 - 0.0024 17.3 0.1 0.013 15.0 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF43840.1 - 0.0033 17.7 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PXF43840.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 PXF43840.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 PXF43840.1 - 0.039 13.7 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF43840.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PXF43840.1 - 0.13 12.7 0.0 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Peptidase_M50 PF02163.22 PXF43841.1 - 0.00024 20.4 1.5 0.00048 19.5 0.7 1.7 1 1 1 2 2 2 1 Peptidase family M50 DEAD PF00270.29 PXF43842.1 - 3.6e-48 163.6 0.0 9.9e-48 162.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43842.1 - 2.3e-29 102.0 0.1 1.3e-28 99.6 0.2 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF43842.1 - 2.2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFAP1 PF06991.11 PXF43842.1 - 0.036 13.9 7.6 0.057 13.3 7.6 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing UTP25 PF06862.12 PXF43842.1 - 0.16 10.7 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glycoprotein_G PF00802.19 PXF43842.1 - 0.47 9.8 2.9 0.7 9.2 2.9 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G MAJIN PF15077.6 PXF43842.1 - 1.7 8.4 5.4 2.8 7.7 5.4 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Exo_endo_phos PF03372.23 PXF43843.1 - 1.7e-14 53.9 0.0 4.4e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PXF43843.1 - 0.018 14.9 0.0 0.095 12.5 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Ndc1_Nup PF09531.10 PXF43843.1 - 0.7 8.5 4.4 0.8 8.3 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWIRM-assoc_2 PF16496.5 PXF43843.1 - 3.7 6.3 11.2 5.1 5.9 11.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MCM_N PF14551.6 PXF43846.1 - 8.5e-06 26.3 0.1 1.6e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 MCM N-terminal domain MCM_OB PF17207.3 PXF43846.1 - 0.001 18.9 0.1 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain DUF4698 PF15769.5 PXF43847.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) MAS20 PF02064.15 PXF43848.1 - 0.099 12.7 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor Abhydrolase_1 PF00561.20 PXF43849.1 - 3.4e-19 69.5 0.0 9.1e-19 68.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF43849.1 - 7.6e-10 39.8 0.0 1e-09 39.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CCSMST1 PF15013.6 PXF43850.1 - 0.046 13.9 0.2 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 CCSMST1 family Casc1_N PF15927.5 PXF43851.1 - 0.48 10.1 11.8 0.56 9.9 11.1 1.5 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus FtsL PF04999.13 PXF43851.1 - 1.1 9.3 5.2 0.79 9.8 1.3 2.1 2 0 0 2 2 2 0 Cell division protein FtsL DUF4288 PF14119.6 PXF43851.1 - 1.4 9.3 6.1 11 6.4 0.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4288) HemolysinCabind PF00353.19 PXF43853.1 - 5.4e-14 51.8 47.4 2.5e-07 30.5 11.7 8.7 7 1 2 9 9 9 5 RTX calcium-binding nonapeptide repeat (4 copies) DUF4854 PF16146.5 PXF43853.1 - 0.013 15.9 0.4 0.078 13.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) 5_nucleotid_C PF02872.18 PXF43855.1 - 1e-29 103.8 0.0 1.9e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PXF43855.1 - 5.4e-11 43.4 0.7 8.8e-11 42.7 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XG_FTase PF03254.13 PXF43856.1 - 0.0056 15.3 0.1 0.0095 14.6 0.1 1.3 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase Octopine_DH PF02317.17 PXF43857.1 - 2e-39 135.1 0.0 2.8e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 PXF43857.1 - 2.7e-09 37.2 0.0 1.5e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 PXF43857.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 PXF43857.1 - 0.0087 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 PXF43857.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 PXF43857.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 PXF43857.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA_C PF08546.11 PXF43857.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal GIDA PF01134.22 PXF43857.1 - 0.16 11.1 0.5 0.39 9.7 0.5 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A JAB PF01398.21 PXF43858.1 - 8e-24 83.9 0.1 1.5e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PXF43858.1 - 7.1e-17 61.8 0.0 1.3e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 PXF43858.1 - 0.021 14.9 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) ATP-synt_DE_N PF02823.16 PXF43859.1 - 9.7e-16 57.4 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ubiquitin PF00240.23 PXF43860.1 - 1.1e-08 34.7 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PXF43860.1 - 0.00017 22.0 0.0 0.00088 19.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PXF43860.1 - 0.066 13.1 0.1 0.21 11.4 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Proteasome PF00227.26 PXF43861.1 - 1.9e-49 167.7 0.1 2.6e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF43861.1 - 1.2e-15 56.9 0.1 2.7e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 PXF43863.1 - 2.7e-06 28.0 5.2 0.57 11.2 0.3 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat UL41A PF17591.2 PXF43863.1 - 0.033 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A Avl9 PF09794.9 PXF43864.1 - 9.1e-59 199.0 0.0 2.6e-42 144.9 0.0 4.1 3 1 1 4 4 4 4 Transport protein Avl9 DUF2347 PF09804.9 PXF43864.1 - 6.7e-07 29.2 0.1 0.0084 15.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 PXF43864.1 - 0.00041 20.3 0.1 0.00074 19.5 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Nic96 PF04097.14 PXF43865.1 - 7.8e-55 186.5 0.1 3.4e-54 184.4 0.1 1.9 1 1 0 1 1 1 1 Nup93/Nic96 TetR_C_1 PF02909.17 PXF43865.1 - 0.042 13.7 0.0 0.35 10.7 0.0 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MIS13 PF08202.11 PXF43865.1 - 0.086 12.1 2.2 2.3 7.4 0.2 2.6 3 0 0 3 3 3 0 Mis12-Mtw1 protein family Rubis-subs-bind PF09273.11 PXF43866.1 - 2.3e-15 57.4 0.2 5.2e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PXF43866.1 - 0.024 15.0 0.0 0.06 13.7 0.0 1.7 2 0 0 2 2 2 0 SET domain zf-MIZ PF02891.20 PXF43867.1 - 2.8e-20 71.8 1.5 2.8e-20 71.8 1.5 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PXF43867.1 - 1.7e-10 40.5 0.6 4.6e-10 39.2 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 PXF43867.1 - 0.0039 17.0 1.7 0.0095 15.8 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF43867.1 - 0.37 10.7 1.7 0.74 9.7 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF43867.1 - 0.49 10.8 1.7 0.98 9.8 1.7 1.5 1 0 0 1 1 1 0 Ring finger domain G6PD_C PF02781.16 PXF43869.1 - 8.5e-114 379.6 0.0 1.3e-113 379.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PXF43869.1 - 6.4e-53 180.0 0.0 9.4e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF5617 PF18493.1 PXF43869.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) RHD3 PF05879.12 PXF43870.1 - 3.6e-72 243.6 0.0 4.4e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 PXF43870.1 - 0.00054 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF43870.1 - 0.014 15.4 0.0 0.042 13.9 0.0 1.9 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 PXF43870.1 - 0.015 15.6 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 PXF43870.1 - 0.018 14.3 0.0 0.049 12.9 0.0 1.7 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF4936 PF16290.5 PXF43870.1 - 0.12 13.1 0.5 0.3 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4936) Roc PF08477.13 PXF43870.1 - 0.21 11.8 0.0 0.7 10.1 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PXF43870.1 - 0.22 11.9 1.6 0.52 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Prefoldin PF02996.17 PXF43871.1 - 6.1e-09 35.8 0.1 7.9e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 Prefoldin subunit Glyco_transf_49 PF13896.6 PXF43872.1 - 6.2e-33 114.5 0.2 3.9e-31 108.6 0.2 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan LSM PF01423.22 PXF43873.1 - 1.8e-15 56.3 0.2 2.4e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF43873.1 - 0.014 15.6 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain CpeS PF09367.10 PXF43874.1 - 2.2e-56 190.4 0.1 3.1e-56 189.9 0.1 1.2 1 0 0 1 1 1 1 CpeS-like protein tRNA-synt_1 PF00133.22 PXF43875.1 - 4.1e-208 692.5 0.1 8.5e-207 688.1 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PXF43875.1 - 9.7e-35 119.8 0.0 1.8e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PXF43875.1 - 1.7e-21 76.4 0.0 1.5e-07 30.6 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 PXF43875.1 - 3.1e-18 65.8 1.8 8.1e-18 64.5 1.8 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 PXF43875.1 - 3.8e-12 46.1 0.0 1.5e-10 40.9 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PXF43875.1 - 0.004 16.5 0.0 0.057 12.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF43875.1 - 0.0099 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 PXF43875.1 - 0.073 13.3 0.3 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain FAP PF07174.11 PXF43875.1 - 0.57 9.6 3.1 0.91 8.9 3.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RRM_1 PF00076.22 PXF43876.1 - 2.7e-34 116.8 0.0 6.3e-16 58.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF43876.1 - 5e-12 45.8 0.1 4.8e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 PXF43876.1 - 0.0025 17.4 0.1 0.39 10.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain Myb_DNA-binding PF00249.31 PXF43877.1 - 1.5e-10 41.1 0.8 3.3e-10 40.0 0.8 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF43877.1 - 0.014 15.7 0.4 0.034 14.4 0.4 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain EF-hand_1 PF00036.32 PXF43878.1 - 3.9e-11 41.7 0.3 0.00032 20.0 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF43878.1 - 1.1e-08 34.3 1.0 0.00057 19.6 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PXF43878.1 - 2e-08 34.6 0.0 3.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PXF43878.1 - 0.00029 20.6 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PXF43878.1 - 0.016 14.7 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 EF hand GNT-I PF03071.15 PXF43879.1 - 1.4e-92 310.8 0.2 1.9e-92 310.3 0.2 1.1 1 0 0 1 1 1 1 GNT-I family ANXA2R PF15721.5 PXF43879.1 - 0.12 12.9 0.5 2.6 8.5 0.1 2.2 1 1 1 2 2 2 0 Annexin-2 receptor LRR_4 PF12799.7 PXF43881.1 - 6.2e-19 67.8 22.5 2e-06 28.0 3.5 6.2 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PXF43881.1 - 5.7e-18 64.4 23.0 3.2e-10 39.6 5.1 5.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 PXF43881.1 - 1.3e-08 34.5 8.8 7.9e-05 22.2 1.7 3.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 PXF43881.1 - 5.4e-05 23.2 0.8 9.8e-05 22.3 0.8 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PXF43881.1 - 0.0022 18.3 15.7 6.8 7.7 0.2 7.3 6 2 0 6 6 6 1 Leucine Rich Repeat DUF4306 PF14154.6 PXF43881.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) LRR_6 PF13516.6 PXF43881.1 - 0.33 11.1 24.6 6.9 7.0 0.2 7.0 7 0 0 7 7 7 0 Leucine Rich repeat zf-UBR PF02207.20 PXF43883.1 - 2e-19 69.5 13.3 7.2e-19 67.7 13.3 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Spc7 PF08317.11 PXF43884.1 - 0.0062 15.5 0.3 0.0088 15.0 0.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.11 PXF43884.1 - 0.23 11.9 3.6 0.74 10.3 1.3 2.3 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 PXF43885.1 - 0.065 13.8 0.4 0.065 13.8 0.4 2.1 3 0 0 3 3 3 0 SlyX ARD PF03079.14 PXF43885.1 - 0.21 11.8 0.3 0.31 11.2 0.3 1.2 1 0 0 1 1 1 0 ARD/ARD' family Cys_Met_Meta_PP PF01053.20 PXF43886.1 - 6.4e-109 364.0 0.0 7.2e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PXF43886.1 - 1.9e-07 30.7 0.2 3.7e-07 29.8 0.2 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PXF43886.1 - 7.4e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PXF43886.1 - 0.0017 17.7 0.2 0.016 14.5 0.2 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Branch PF02485.21 PXF43887.1 - 3e-33 115.3 0.3 4.9e-33 114.7 0.3 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme zf-C3HC4_2 PF13923.6 PXF43888.1 - 0.0016 18.2 7.7 0.0032 17.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MIT PF04212.18 PXF43888.1 - 0.0021 18.1 0.8 0.005 16.9 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SR-25 PF10500.9 PXF43888.1 - 0.013 15.1 11.7 0.03 14.0 11.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubredoxin_2 PF18073.1 PXF43888.1 - 0.017 14.8 2.1 0.031 14.0 2.1 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain zf-C3HC4_3 PF13920.6 PXF43888.1 - 0.035 14.0 7.2 0.065 13.1 7.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF43888.1 - 0.6 10.0 8.1 1.1 9.2 8.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PXF43888.1 - 1 9.3 9.9 2 8.4 9.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF43888.1 - 2.6 8.1 9.9 5.7 7.0 9.9 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 PXF43888.1 - 4.8 7.6 8.7 8.6 6.8 8.7 1.4 1 0 0 1 1 1 0 Ring finger domain Peptidase_M76 PF09768.9 PXF43889.1 - 4.8e-63 212.0 4.7 5.5e-63 211.8 4.7 1.0 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.6 PXF43889.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M90 PF06167.12 PXF43889.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 SprT-like PF10263.9 PXF43889.1 - 0.1 12.5 1.0 0.17 11.8 0.7 1.6 1 1 0 1 1 1 0 SprT-like family DUF1764 PF08576.10 PXF43890.1 - 1.6e-13 51.4 3.5 1.6e-13 51.4 3.5 3.9 3 1 1 4 4 4 1 Eukaryotic protein of unknown function (DUF1764) DHQ_synthase PF01761.20 PXF43891.1 - 1.3e-106 355.6 0.0 1.6e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 PXF43891.1 - 2.5e-14 53.6 0.7 3.6e-13 49.8 0.7 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 PXF43891.1 - 2.8e-09 36.3 1.6 4.8e-09 35.5 0.6 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DUF3253 PF11625.8 PXF43892.1 - 1e-23 83.3 0.0 1.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) tRNA_m1G_MT PF01746.21 PXF43893.1 - 3e-16 59.7 0.0 5.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF1682 PF07946.14 PXF43893.1 - 0.1 11.8 13.9 0.82 8.8 15.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) XET_C PF06955.12 PXF43893.1 - 0.16 11.8 1.2 1.1 9.2 0.0 2.7 2 1 1 3 3 3 0 Xyloglucan endo-transglycosylase (XET) C-terminus Atg14 PF10186.9 PXF43893.1 - 0.23 10.5 10.5 0.34 9.9 10.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_pol_3_Rpc31 PF11705.8 PXF43893.1 - 0.3 11.3 4.6 0.49 10.6 4.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CagY_M PF07337.11 PXF43893.1 - 0.34 10.6 4.0 0.91 9.2 1.4 2.7 2 0 0 2 2 2 0 DC-EC Repeat Kri1 PF05178.12 PXF43893.1 - 2.1 8.9 11.9 1.8 9.2 10.3 1.7 1 1 0 1 1 1 0 KRI1-like family MAJIN PF15077.6 PXF43893.1 - 3.5 7.3 7.8 5.2 6.8 7.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein PVL_ORF50 PF07768.11 PXF43893.1 - 7 7.0 14.2 21 5.4 14.2 1.7 1 1 0 1 1 1 0 PVL ORF-50-like family RCC1 PF00415.18 PXF43894.1 - 5.2e-34 116.6 17.0 2.3e-10 40.9 0.1 7.1 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF43894.1 - 2e-27 94.3 23.1 5.9e-07 29.1 0.4 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF913 PF06025.12 PXF43895.1 - 1.3e-36 126.4 0.0 1.3e-36 126.4 0.0 3.0 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 PXF43895.1 - 1.3e-31 110.4 10.0 6.6e-31 108.0 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) UBA PF00627.31 PXF43895.1 - 0.0013 18.6 0.0 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain DUF4042 PF13251.6 PXF43895.1 - 0.0036 17.0 0.7 0.013 15.2 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) RNase_HII PF01351.18 PXF43895.1 - 0.028 14.3 2.2 0.085 12.7 1.2 2.4 2 0 0 2 2 2 0 Ribonuclease HII DUF2524 PF10732.9 PXF43895.1 - 0.2 12.0 0.9 0.96 9.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Fib_alpha PF08702.10 PXF43895.1 - 4.4 7.5 6.6 1.5 9.0 2.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ceramidase_alk PF04734.13 PXF43896.1 - 2.8e-06 26.3 0.0 7.1e-06 24.9 0.0 1.7 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal ATP-synt_Eps PF04627.13 PXF43897.1 - 9.8e-17 60.7 0.5 1.2e-16 60.4 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain tRNA-synt_1 PF00133.22 PXF43898.1 - 2.6e-183 610.5 0.0 3.4e-183 610.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PXF43898.1 - 1.8e-28 99.4 0.0 3.1e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PXF43898.1 - 2.7e-19 69.2 0.0 2.9e-10 39.5 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 PXF43898.1 - 2.6e-07 30.3 3.3 5.9e-07 29.2 3.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 PXF43898.1 - 0.049 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Kin17_mid PF10357.9 PXF43899.1 - 2.9e-40 137.1 1.2 2.9e-40 137.1 1.2 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PXF43899.1 - 7e-18 64.5 0.4 1.9e-14 53.5 0.1 2.7 2 0 0 2 2 2 2 KN17 SH3-like C-terminal domain KOW PF00467.29 PXF43899.1 - 1.2e-06 28.3 7.4 0.00018 21.4 0.4 2.9 2 0 0 2 2 2 2 KOW motif zf-met PF12874.7 PXF43899.1 - 0.0017 18.7 5.2 0.0054 17.1 5.2 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF43899.1 - 0.014 15.7 4.8 0.014 15.7 4.8 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF43899.1 - 0.025 14.9 2.4 0.077 13.3 0.4 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_S6e PF01092.19 PXF43899.1 - 0.067 13.2 0.2 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S6e Ribosomal_L9_N PF01281.19 PXF43899.1 - 0.15 11.6 3.0 0.76 9.4 0.4 2.8 3 0 0 3 3 3 0 Ribosomal protein L9, N-terminal domain CHGN PF05679.16 PXF43900.1 - 3e-52 178.1 0.0 5.5e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase DEAD PF00270.29 PXF43901.1 - 6.5e-47 159.6 0.1 4.2e-46 156.9 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43901.1 - 6.5e-25 87.6 0.1 4.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 PXF43901.1 - 1.3e-15 57.4 0.0 5.2e-15 55.5 0.0 2.1 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 PXF43901.1 - 2.5e-05 24.3 0.0 2.5e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PXF43901.1 - 0.012 15.0 13.6 0.02 14.3 0.0 3.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF2151 PF10221.9 PXF43901.1 - 0.42 9.2 5.3 0.57 8.7 5.3 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator NARP1 PF12569.8 PXF43901.1 - 5 5.9 17.5 7.2 5.4 17.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 bZIP_2 PF07716.15 PXF43902.1 - 0.00021 21.3 8.8 0.00021 21.3 8.8 1.5 1 1 0 1 1 1 1 Basic region leucine zipper YabA PF06156.13 PXF43902.1 - 0.0077 16.8 0.2 0.011 16.3 0.2 1.3 1 0 0 1 1 1 1 Initiation control protein YabA NYD-SP28_assoc PF14775.6 PXF43902.1 - 0.12 12.5 0.4 0.12 12.5 0.4 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Macoilin PF09726.9 PXF43902.1 - 0.12 10.9 1.8 0.15 10.6 1.8 1.0 1 0 0 1 1 1 0 Macoilin family Shugoshin_N PF07558.11 PXF43902.1 - 0.12 12.2 8.4 0.23 11.3 0.5 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 PXF43902.1 - 0.13 12.5 8.9 0.055 13.7 6.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4686 PF15742.5 PXF43902.1 - 0.13 11.4 4.4 0.18 10.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Allexi_40kDa PF05549.11 PXF43902.1 - 0.13 11.7 1.1 0.23 11.0 1.1 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein TSC22 PF01166.18 PXF43902.1 - 0.14 12.5 1.0 0.23 11.8 1.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 PXF43902.1 - 0.18 11.9 6.4 0.24 11.4 6.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 PXF43902.1 - 0.72 10.0 15.5 2.3 8.4 15.5 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 PXF43902.1 - 0.92 10.1 8.2 1.4 9.5 8.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor AA_kinase PF00696.28 PXF43903.1 - 1.3e-36 126.4 0.5 1.6e-36 126.1 0.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family Homeobox_KN PF05920.11 PXF43904.1 - 8.6e-13 48.0 0.2 2e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PXF43904.1 - 5.7e-12 45.3 0.2 1.4e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 Homeodomain TamB PF04357.13 PXF43904.1 - 2.3e-07 30.4 0.2 1.4e-05 24.6 0.1 3.3 3 1 0 3 3 3 1 TamB, inner membrane protein subunit of TAM complex DUF3971 PF13116.6 PXF43904.1 - 0.00078 19.1 0.0 0.089 12.3 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function EMP24_GP25L PF01105.24 PXF43906.1 - 9.9e-20 71.2 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IF3_C PF00707.22 PXF43907.1 - 6.8e-14 51.6 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 PXF43907.1 - 8.6e-12 45.2 0.1 1.8e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain SOAR PF16533.5 PXF43907.1 - 0.027 14.4 4.9 0.031 14.3 3.7 1.6 1 1 0 1 1 1 0 STIM1 Orai1-activating region AMP-binding_C PF13193.6 PXF43908.1 - 2.1e-07 31.8 0.0 5.3e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain KCT2 PF17818.1 PXF43908.1 - 0.068 13.3 0.3 0.068 13.3 0.3 1.7 1 1 1 2 2 2 0 Keratinocyte-associated gene product Exonuc_VII_L PF02601.15 PXF43908.1 - 0.12 11.9 4.0 0.16 11.5 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ECH_1 PF00378.20 PXF43909.1 - 1.9e-75 253.4 0.0 2.4e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PXF43909.1 - 2.9e-16 59.9 0.0 3.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chorismate_bind PF00425.18 PXF43910.1 - 1.9e-51 175.1 0.0 8e-51 173.1 0.0 1.9 1 1 0 1 1 1 1 chorismate binding enzyme TPP_enzyme_N PF02776.18 PXF43910.1 - 3.9e-30 104.7 0.1 9.8e-30 103.4 0.1 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 PXF43910.1 - 4.7e-09 36.3 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate Peptidase_S8 PF00082.22 PXF43911.1 - 2.4e-36 125.5 5.0 4e-36 124.8 5.0 1.3 1 0 0 1 1 1 1 Subtilase family Topoisom_bac PF01131.20 PXF43912.1 - 3.5e-98 329.3 0.0 4.6e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PXF43912.1 - 1.2e-14 54.4 0.0 3.2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 PXF43912.1 - 0.0017 18.1 3.4 0.0017 18.1 3.4 3.1 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Cys_rich_CPCC PF14206.6 PXF43912.1 - 7.7 6.4 9.1 0.55 10.1 0.2 3.4 4 0 0 4 4 4 0 Cysteine-rich CPCC SNAP PF14938.6 PXF43913.1 - 5.6e-95 318.0 25.6 6.4e-95 317.8 25.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP CdiI_2 PF18593.1 PXF43913.1 - 0.014 16.0 1.7 0.035 14.8 0.5 2.2 2 0 0 2 2 2 0 CdiI immunity protein DHR-2 PF06920.13 PXF43913.1 - 0.016 13.9 4.1 0.025 13.2 4.1 1.3 1 0 0 1 1 1 0 Dock homology region 2 PTS_IIA PF02255.16 PXF43913.1 - 0.26 11.4 10.1 1.2 9.2 1.3 3.5 1 1 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit DXPR_C PF13288.6 PXF43913.1 - 1 9.7 5.4 2.2 8.6 0.0 2.7 2 1 0 2 2 2 0 DXP reductoisomerase C-terminal domain TPR_6 PF13174.6 PXF43913.1 - 1.5 9.6 10.6 2.3 9.1 0.2 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Nsp1_C PF05064.13 PXF43914.1 - 9.7e-23 80.2 1.9 2.1e-22 79.1 1.9 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 PXF43914.1 - 0.0037 18.1 48.4 0.0097 16.7 24.4 6.6 1 1 4 5 5 5 2 Nucleoporin FG repeat region Corona_S2 PF01601.16 PXF43914.1 - 0.17 10.3 0.2 0.27 9.7 0.2 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prefoldin_2 PF01920.20 PXF43914.1 - 0.27 11.2 0.9 0.77 9.7 0.3 1.8 2 0 0 2 2 2 0 Prefoldin subunit Pkinase PF00069.25 PXF43915.1 - 1.7e-58 198.0 0.0 3.1e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43915.1 - 2.6e-31 108.8 0.0 3.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43915.1 - 1.2e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PXF43915.1 - 0.0086 14.9 0.6 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 PXF43916.1 - 5.2e-63 212.9 0.0 3e-62 210.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43916.1 - 1.3e-36 126.2 0.0 1.7e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF43916.1 - 6.6e-08 32.2 0.0 3.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PXF43916.1 - 0.011 14.5 0.0 0.035 12.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 PXF43916.1 - 0.016 14.8 0.0 5.5 6.6 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Requiem_N PF14051.6 PXF43916.1 - 0.25 11.6 0.6 15 5.9 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain of DPF2/REQ. Prp18 PF02840.15 PXF43920.1 - 1.2e-49 168.1 3.9 1.2e-49 168.1 3.9 1.9 2 0 0 2 2 2 1 Prp18 domain Ndc1_Nup PF09531.10 PXF43920.1 - 6.7 5.3 11.5 8.4 4.9 11.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.27 PXF43921.1 - 2.4e-22 79.9 0.0 3.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF43921.1 - 1.7e-10 41.2 0.3 0.00037 20.4 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF43921.1 - 2.7e-08 33.5 0.0 0.00062 19.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PXF43921.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF43921.1 - 0.00094 19.0 0.1 0.0012 18.6 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 PXF43921.1 - 0.0051 17.3 0.1 0.01 16.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF43921.1 - 0.038 14.3 0.1 0.094 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 PXF43921.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PXF43921.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 PXF43921.1 - 0.067 13.6 0.2 0.17 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PXF43921.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 PXF43921.1 - 0.12 12.1 0.2 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SbcCD_C PF13558.6 PXF43921.1 - 0.18 12.0 0.0 0.49 10.7 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Fib_alpha PF08702.10 PXF43922.1 - 0.073 13.3 5.1 3.7 7.7 0.5 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF733 PF05306.11 PXF43922.1 - 2.5 8.5 11.5 8 6.8 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Pkinase PF00069.25 PXF43923.1 - 5.4e-32 111.2 0.0 6e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43923.1 - 2.1e-18 66.6 0.0 2.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF43923.1 - 0.0002 20.3 0.0 0.00031 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF43923.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2207 PF09972.9 PXF43924.1 - 0.0014 17.5 0.1 0.47 9.2 0.0 2.0 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Epiglycanin_C PF14654.6 PXF43924.1 - 0.051 13.6 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Peptidase_S24 PF00717.23 PXF43926.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 PXF43926.1 - 4.2e-05 23.4 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 LPMO_10 PF03067.15 PXF43927.1 - 1.7e-20 74.6 3.4 2.3e-20 74.1 3.4 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Big_7 PF17957.1 PXF43927.1 - 0.17 12.6 0.1 2.3 9.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial Ig domain ABC2_membrane PF01061.24 PXF43928.1 - 2e-35 122.1 30.9 2e-35 122.1 30.9 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PXF43928.1 - 5.6e-20 72.2 0.0 9.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PXF43928.1 - 5.8e-05 22.4 26.1 9e-05 21.7 26.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PXF43928.1 - 6.3e-05 23.4 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PXF43928.1 - 0.00027 20.6 0.0 0.00063 19.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PXF43928.1 - 0.0006 19.7 0.5 0.24 11.2 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PXF43928.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PXF43928.1 - 0.004 16.6 0.0 0.047 13.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF43928.1 - 0.0047 17.2 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PXF43928.1 - 0.061 12.9 0.1 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PXF43928.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.8 PXF43928.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) AAA_PrkA PF08298.11 PXF43928.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain PIF1 PF05970.14 PXF43928.1 - 0.19 10.9 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase FBPase PF00316.20 PXF43930.1 - 8.8e-61 204.7 1.0 1.2e-60 204.2 1.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 PXF43930.1 - 0.0056 16.2 0.0 0.094 12.2 0.0 2.1 2 0 0 2 2 2 1 Inositol monophosphatase family Aa_trans PF01490.18 PXF43931.1 - 2.5e-54 184.6 20.3 1.6e-49 168.8 13.4 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Glyco_transf_20 PF00982.21 PXF43932.1 - 1.6e-190 633.9 0.0 1.9e-190 633.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PXF43932.1 - 9.2e-47 159.1 0.0 1.4e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 PXF43932.1 - 0.00012 21.6 0.1 0.0007 19.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Hydrolase_3 PF08282.12 PXF43932.1 - 0.026 14.2 0.0 2.3 7.9 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Bac_surface_Ag PF01103.23 PXF43933.1 - 4.7e-38 131.5 0.0 6.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 PXF43933.1 - 6.5e-05 22.5 0.1 0.025 14.0 0.0 2.3 1 1 0 2 2 2 2 Haemolysin secretion/activation protein ShlB/FhaC/HecB zf-H2C2_2 PF13465.6 PXF43934.1 - 1.8e-05 25.0 8.2 0.018 15.5 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PXF43934.1 - 0.031 14.6 3.9 0.68 10.3 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PXF43934.1 - 0.24 12.3 6.6 3.1 8.9 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.11 PXF43934.1 - 0.28 11.5 4.4 0.7 10.2 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) zf-C2H2 PF00096.26 PXF43934.1 - 0.28 11.7 7.3 1.9 9.1 2.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type IL11 PF07400.11 PXF43935.1 - 0.00011 21.9 0.3 0.0036 17.0 0.0 2.0 1 1 1 2 2 2 2 Interleukin 11 Med8 PF10232.9 PXF43935.1 - 0.0067 16.1 0.3 0.013 15.1 0.1 1.6 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 Hint PF01079.20 PXF43936.1 - 0.16 11.5 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Hint module GAT PF03127.14 PXF43937.1 - 7.4e-08 32.6 2.9 1.8e-07 31.3 2.9 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 PXF43937.1 - 0.0003 20.7 0.0 0.0026 17.6 0.0 2.3 3 0 0 3 3 3 1 VHS domain HEAT PF02985.22 PXF43938.1 - 8e-10 38.1 7.2 1.4 9.4 0.0 8.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 PXF43938.1 - 6e-09 36.2 17.0 9.2e-05 22.9 0.1 7.6 7 1 1 8 8 8 2 HEAT-like repeat IBN_N PF03810.19 PXF43938.1 - 1e-08 35.0 0.0 5.7e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 PXF43938.1 - 6.5e-06 26.4 23.7 0.94 9.9 0.0 7.1 3 2 6 9 9 9 4 HEAT repeats Secretin_N PF03958.17 PXF43938.1 - 0.0057 17.0 0.0 8.5 6.9 0.0 2.9 2 0 0 2 2 2 2 Bacterial type II/III secretion system short domain Vac14_Fab1_bd PF12755.7 PXF43938.1 - 0.016 15.7 0.3 2.2 9.0 0.0 4.1 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PXF43938.1 - 0.02 14.9 0.4 2.3 8.2 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ribosomal_L36e PF01158.18 PXF43939.1 - 2e-39 133.8 6.2 2.1e-39 133.6 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e SLED PF12140.8 PXF43939.1 - 0.042 14.4 0.1 0.049 14.1 0.1 1.1 1 0 0 1 1 1 0 SLED domain PBS_linker_poly PF00427.21 PXF43939.1 - 0.083 12.9 0.2 0.097 12.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 PXF43939.1 - 0.15 10.8 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Aminotran_3 PF00202.21 PXF43940.1 - 1.1e-118 396.4 0.0 1.3e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Hexapep PF00132.24 PXF43941.1 - 2.4e-10 39.7 0.2 0.0014 18.2 0.1 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PXF43941.1 - 0.015 15.0 1.5 3.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase FapA PF03961.13 PXF43945.1 - 0.046 12.3 2.2 0.053 12.1 2.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A GvpL_GvpF PF06386.11 PXF43945.1 - 4.6 7.1 8.8 8.3 6.3 8.8 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Hydrolase_3 PF08282.12 PXF43947.1 - 2.5e-53 181.4 0.0 2.9e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF43947.1 - 6.2e-14 52.1 0.1 9e-11 41.8 0.1 2.5 2 1 1 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PXF43947.1 - 1.4e-07 32.1 0.1 6.3e-07 29.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 PXF43947.1 - 0.00024 20.3 0.0 0.001 18.2 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase HAD_2 PF13419.6 PXF43947.1 - 0.0037 17.4 1.1 0.012 15.7 0.1 2.2 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF43947.1 - 0.014 15.8 0.0 1.1 9.7 0.0 3.0 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 PXF43948.1 - 4.4e-61 206.6 0.0 5.4e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43948.1 - 2.5e-43 148.3 0.0 3.3e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF43948.1 - 5.5e-08 32.0 0.0 9.6e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PBD PF00786.28 PXF43948.1 - 8.8e-06 26.0 0.7 0.00042 20.6 0.0 2.5 1 1 1 2 2 2 1 P21-Rho-binding domain Kdo PF06293.14 PXF43948.1 - 0.029 13.7 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF43948.1 - 0.053 13.4 0.0 3 7.7 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 PXF43948.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Adeno_PV PF03910.13 PXF43949.1 - 1.8 7.2 6.4 2.8 6.6 6.4 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV Ephrin_rec_like PF07699.13 PXF43951.1 - 2e-30 104.3 134.5 3.2e-06 26.8 9.8 15.4 1 1 15 17 17 17 14 Putative ephrin-receptor like NCD3G PF07562.14 PXF43951.1 - 2.3e-15 56.3 101.4 0.00057 19.8 3.0 13.4 5 5 5 13 13 13 10 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 PXF43951.1 - 0.014 14.3 93.4 0.1 11.5 12.2 6.3 1 1 5 6 6 6 0 Giardia variant-specific surface protein Plant_tran PF04827.14 PXF43957.1 - 9.7e-24 84.1 0.9 1.3e-23 83.7 0.9 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF43957.1 - 0.00035 20.3 0.2 0.0005 19.8 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease EIIBC-GUT_N PF03612.14 PXF43957.1 - 0.048 13.4 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDE_Tnp_1_2 PF13586.6 PXF43957.1 - 0.055 13.8 0.2 0.12 12.8 0.2 1.6 1 0 0 1 1 1 0 Transposase DDE domain Med18 PF09637.10 PXF43958.1 - 3.8e-05 23.7 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Med18 protein YchF-GTPase_C PF06071.13 PXF43959.1 - 1e-35 121.8 0.2 2.6e-35 120.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PXF43959.1 - 5.6e-21 74.8 0.0 1.2e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF43959.1 - 1.6e-07 31.0 0.0 4.1e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 PXF43959.1 - 0.00025 21.3 0.0 0.05 13.8 0.0 2.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TGS PF02824.21 PXF43959.1 - 0.057 13.5 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 TGS domain ABC_tran PF00005.27 PXF43959.1 - 0.17 12.4 0.0 1.2 9.6 0.0 2.1 2 1 0 2 2 2 0 ABC transporter LPMO_10 PF03067.15 PXF43961.1 - 2.5e-23 83.8 1.1 4.3e-23 83.0 1.1 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FhuF_C PF11575.8 PXF43961.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.0 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain XRN_M PF17846.1 PXF43962.1 - 9.5e-124 413.7 14.7 2.2e-123 412.5 3.1 3.8 3 1 0 3 3 3 1 Xrn1 helical domain XRN_N PF03159.18 PXF43962.1 - 1.8e-98 328.8 0.3 3.7e-98 327.8 0.3 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CHD5 PF04420.14 PXF43962.1 - 0.15 11.9 0.6 0.53 10.1 0.6 1.9 1 0 0 1 1 1 0 CHD5-like protein Helicase_C PF00271.31 PXF43963.1 - 6.8e-10 39.3 0.0 2.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AroM PF07302.11 PXF43963.1 - 0.16 11.4 1.0 6.2 6.2 0.1 2.5 2 1 0 2 2 2 0 AroM protein Nucleotid_trans PF03407.16 PXF43964.1 - 0.0013 18.7 0.8 0.0014 18.6 0.8 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase C2 PF00168.30 PXF43966.1 - 4.7e-15 55.7 0.0 1.5e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 C2 domain PLD_C PF12357.8 PXF43966.1 - 6.4e-14 51.6 0.1 2.7e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Phospholipase D C terminal PLDc PF00614.22 PXF43966.1 - 3.5e-09 36.5 7.3 2.6e-06 27.4 0.1 3.6 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PXF43966.1 - 4.5e-09 36.3 0.2 4.1e-07 29.9 0.1 3.2 3 1 0 3 3 3 1 PLD-like domain Ribul_P_3_epim PF00834.19 PXF43968.1 - 2e-87 291.7 0.0 2.4e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Syja_N PF02383.18 PXF43969.1 - 6.5e-79 265.6 0.0 8.4e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Adaptin_N PF01602.20 PXF43970.1 - 5.2e-78 262.9 5.0 8.1e-78 262.3 5.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 PXF43970.1 - 6.4e-53 178.1 0.1 5.1e-52 175.2 0.0 2.5 2 1 0 3 3 3 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 PXF43970.1 - 3e-46 156.8 0.7 5.6e-46 155.9 0.7 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 PXF43970.1 - 8.2e-07 29.3 1.1 0.002 18.4 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 PXF43970.1 - 4.2e-06 26.9 0.7 0.0041 17.2 0.1 3.2 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PXF43970.1 - 1.2e-05 25.2 0.1 0.027 14.7 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat GUN4_N PF16416.5 PXF43970.1 - 0.2 11.7 0.3 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal p450 PF00067.22 PXF43972.1 - 2.1e-51 175.1 1.0 2.8e-51 174.7 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 PXF43973.1 - 2.6e-39 135.2 0.0 4.4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF43973.1 - 2.6e-33 115.4 0.0 3.2e-32 111.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PXF43973.1 - 0.094 12.6 0.2 0.46 10.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PXF43973.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helicase_C PF00271.31 PXF43975.1 - 4e-18 65.8 0.1 1.1e-17 64.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-GRF PF06839.12 PXF43975.1 - 5.7e-14 51.9 0.2 1.3e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 GRF zinc finger DEAD PF00270.29 PXF43975.1 - 1.7e-13 50.7 0.0 4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF43975.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_11 PF08241.12 PXF43977.1 - 2.9e-23 82.3 0.0 4.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF43977.1 - 1.6e-22 80.0 0.0 2.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF43977.1 - 1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF43977.1 - 2.6e-17 63.0 0.0 8.2e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PXF43977.1 - 7.3e-14 52.3 0.0 1.2e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF43977.1 - 8.9e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF43977.1 - 3.8e-05 23.3 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PXF43977.1 - 0.0016 17.9 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 PXF43977.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.7 PXF43977.1 - 0.0058 16.6 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 PXF43977.1 - 0.029 12.9 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 PXF43977.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PXF43977.1 - 0.062 12.7 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 PXF43977.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.6 PXF43977.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Prok-RING_1 PF14446.6 PXF43977.1 - 0.45 10.5 4.1 11 6.0 0.5 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.10 PXF43977.1 - 6.4 6.6 7.0 9.7 6.0 1.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-TFIIB PF13453.6 PXF43977.1 - 8 5.9 6.5 9.7 5.6 4.4 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger DEAD PF00270.29 PXF43978.1 - 2.2e-40 138.3 0.0 4e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF43978.1 - 4.3e-31 107.5 0.0 9.6e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF43978.1 - 1.8e-06 28.1 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF43978.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PXF43978.1 - 0.00055 20.4 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF43978.1 - 0.0007 19.9 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF43978.1 - 0.0027 18.0 0.5 0.023 15.0 0.2 2.3 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 PXF43978.1 - 0.0035 17.2 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Helicase CMS1 PF14617.6 PXF43978.1 - 0.015 14.6 0.1 0.092 12.1 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.16 PXF43978.1 - 0.017 14.6 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 PXF43978.1 - 0.064 12.8 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PXF43978.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 NACHT domain CCB1 PF12046.8 PXF43979.1 - 3.8e-34 117.5 0.1 4.7e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B Phage_holin_2_4 PF16082.5 PXF43979.1 - 0.083 12.6 0.2 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like UPF0240 PF06784.11 PXF43980.1 - 2.2e-10 40.9 0.0 2.8e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) MRP-L20 PF12824.7 PXF43980.1 - 2.1e-05 24.8 3.6 0.00011 22.4 3.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HDV_ag PF01517.18 PXF43982.1 - 0.01 15.7 1.4 0.014 15.2 1.4 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen WAC_Acf1_DNA_bd PF10537.9 PXF43982.1 - 0.011 16.3 0.4 0.019 15.5 0.4 1.4 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal NAM-associated PF14303.6 PXF43982.1 - 1.3 9.7 10.3 0.42 11.3 7.3 1.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain SoxZ PF08770.11 PXF43987.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ PAS_8 PF13188.7 PXF43989.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 PAS domain Tnp_zf-ribbon_2 PF13842.6 PXF43989.1 - 0.032 15.0 2.8 0.076 13.8 2.8 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon AAA_16 PF13191.6 PXF43989.1 - 0.053 13.9 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DDE_Tnp_1_7 PF13843.6 PXF43989.1 - 0.053 12.8 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Transposase IS4 LANC_like PF05147.13 PXF43989.1 - 0.088 11.4 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein C1_2 PF03107.16 PXF43989.1 - 6.7 7.1 6.0 0.69 10.3 0.9 2.0 2 0 0 2 2 2 0 C1 domain Form_Nir_trans PF01226.17 PXF43993.1 - 1.1e-73 247.5 26.4 1.4e-73 247.1 26.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Met_synt_B12 PF02965.17 PXF43994.1 - 4.6e-25 88.6 0.0 1.6e-24 86.8 0.0 1.8 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.17 PXF43994.1 - 4.7e-25 87.8 0.2 2e-24 85.8 0.2 2.2 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 PXF43994.1 - 8.4e-20 71.0 0.3 2e-19 69.8 0.3 1.7 1 0 0 1 1 1 1 B12 binding domain Pterin_bind PF00809.22 PXF43994.1 - 3.6e-19 69.4 0.0 8.1e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme DUF2286 PF10051.9 PXF43994.1 - 0.16 11.7 0.7 21 4.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) DUF1744 PF08490.12 PXF43995.1 - 3e-83 279.6 0.0 6.6e-83 278.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 PXF43995.1 - 2.5e-54 184.7 0.0 5.5e-54 183.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 PXF43995.1 - 9.1e-14 51.0 0.2 2.5e-12 46.3 0.1 3.0 3 1 0 3 3 3 1 DNA polymerase family B RNase_H_2 PF13482.6 PXF43995.1 - 6.6e-09 36.0 0.0 1.8e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 PXF43995.1 - 5.6e-07 29.4 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Melibiase PF02065.18 PXF43996.1 - 2.8e-149 496.8 0.0 4.6e-149 496.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 PXF43996.1 - 1.7e-70 237.5 0.0 1.3e-68 231.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 PXF43996.1 - 1.2e-14 54.6 0.0 2.9e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain DUF1752 PF08550.10 PXF43996.1 - 1.8e-06 27.7 2.1 5.3e-06 26.2 2.1 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_hydro_31 PF01055.26 PXF43996.1 - 5e-05 22.7 0.0 7.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 PXF43996.1 - 0.00091 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A zf-RING_5 PF14634.6 PXF43997.1 - 3.5e-05 23.7 7.9 7.9e-05 22.5 7.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Hemerythrin PF01814.23 PXF43997.1 - 0.0015 19.1 3.7 0.0038 17.8 2.6 1.9 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain Filament PF00038.21 PXF43997.1 - 0.0016 18.1 6.9 0.0026 17.4 6.9 1.4 1 0 0 1 1 1 1 Intermediate filament protein bZIP_1 PF00170.21 PXF43997.1 - 0.004 17.2 6.9 0.034 14.2 2.7 2.6 2 0 0 2 2 2 1 bZIP transcription factor Rootletin PF15035.6 PXF43997.1 - 0.0096 16.0 8.8 0.0096 16.0 8.8 1.7 2 0 0 2 2 1 1 Ciliary rootlet component, centrosome cohesion CENP-K PF11802.8 PXF43997.1 - 0.01 15.5 1.8 0.016 14.8 1.8 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF3584 PF12128.8 PXF43997.1 - 0.012 13.2 10.0 0.017 12.7 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 PXF43997.1 - 0.013 15.5 5.8 0.022 14.8 5.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 PXF43997.1 - 0.013 15.5 5.2 0.023 14.7 5.2 1.4 1 0 0 1 1 1 0 Laminin Domain II HALZ PF02183.18 PXF43997.1 - 0.016 15.4 4.6 0.23 11.7 1.8 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper HOOK PF05622.12 PXF43997.1 - 0.018 13.2 7.5 0.024 12.8 7.5 1.1 1 0 0 1 1 1 0 HOOK protein Fungal_TACC PF12709.7 PXF43997.1 - 0.018 15.5 5.4 2.3 8.7 0.1 2.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 PXF43997.1 - 0.026 14.8 4.6 1.2 9.6 2.6 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 PXF43997.1 - 0.047 13.9 6.6 2 8.6 0.5 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II kleA_kleC PF17383.2 PXF43997.1 - 0.049 14.0 1.8 5.2 7.5 0.7 2.6 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A ZapB PF06005.12 PXF43997.1 - 0.054 13.9 9.6 0.045 14.2 7.2 2.1 1 1 1 2 2 2 0 Cell division protein ZapB BCAS2 PF05700.11 PXF43997.1 - 0.06 13.0 6.9 0.11 12.2 6.9 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) GAS PF13851.6 PXF43997.1 - 0.063 12.6 10.4 0.11 11.8 10.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 PXF43997.1 - 0.068 11.7 7.5 0.11 11.1 7.5 1.3 1 0 0 1 1 1 0 Macoilin family APC_N_CC PF16689.5 PXF43997.1 - 0.068 13.2 0.2 0.068 13.2 0.2 2.1 2 0 0 2 2 1 0 Coiled-coil N-terminus of APC, dimerisation domain Spore_IV_A PF09547.10 PXF43997.1 - 0.071 12.0 0.1 0.097 11.6 0.1 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Seryl_tRNA_N PF02403.22 PXF43997.1 - 0.086 13.1 4.7 0.2 11.9 4.7 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 PXF43997.1 - 0.097 12.7 10.1 0.23 11.5 5.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MAT1 PF06391.13 PXF43997.1 - 0.097 12.5 7.5 0.03 14.2 4.1 1.8 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 TPR_MLP1_2 PF07926.12 PXF43997.1 - 0.1 12.6 10.6 0.24 11.5 10.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 PXF43997.1 - 0.16 10.8 8.3 0.26 10.1 8.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 PXF43997.1 - 0.18 10.4 3.0 0.25 9.9 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 PXF43997.1 - 0.21 11.4 10.9 0.8 9.5 1.6 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH zf-C3HC4_2 PF13923.6 PXF43997.1 - 0.24 11.3 4.6 0.47 10.3 4.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF43997.1 - 0.24 11.7 8.5 0.45 10.9 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain DivIC PF04977.15 PXF43997.1 - 0.24 11.2 9.6 0.11 12.3 1.9 2.5 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 PXF43997.1 - 0.37 11.1 6.0 0.48 10.7 4.0 2.1 1 1 2 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Synaptobrevin PF00957.21 PXF43997.1 - 0.42 10.4 2.0 0.76 9.6 1.2 1.9 1 1 0 1 1 1 0 Synaptobrevin Cnn_1N PF07989.11 PXF43997.1 - 0.57 10.4 6.7 0.67 10.1 4.6 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 PXF43997.1 - 0.63 10.4 6.8 1.3 9.4 6.8 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1515 PF07439.11 PXF43997.1 - 0.68 10.0 2.6 1.7 8.7 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) KLRAQ PF10205.9 PXF43997.1 - 0.7 10.2 8.0 0.74 10.1 5.2 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Fez1 PF06818.15 PXF43997.1 - 0.78 10.2 10.9 0.26 11.7 7.7 1.8 2 0 0 2 2 2 0 Fez1 FlaC_arch PF05377.11 PXF43997.1 - 0.8 10.1 2.3 5.9 7.4 0.5 2.7 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 PXF43997.1 - 0.82 9.7 14.2 1.6 8.8 14.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 PXF43997.1 - 1.1 9.3 7.2 1.9 8.5 6.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 PXF43997.1 - 1.1 9.9 7.0 4.1 8.1 7.0 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 PXF43997.1 - 1.3 9.1 4.8 2.7 8.1 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 PXF43997.1 - 1.4 6.7 9.2 0.53 8.2 6.8 1.3 1 1 0 1 1 1 0 Prominin XhlA PF10779.9 PXF43997.1 - 1.5 9.1 4.3 2.3 8.5 2.6 2.1 2 0 0 2 2 1 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 PXF43997.1 - 1.7 8.9 10.9 2.8 8.2 10.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 PXF43997.1 - 3.1 8.3 9.5 6.8 7.2 2.8 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C3HC4_3 PF13920.6 PXF43997.1 - 3.4 7.6 7.1 7.4 6.5 7.1 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V_ATPase_I PF01496.19 PXF43997.1 - 3.8 5.3 5.6 5 4.9 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.12 PXF43997.1 - 4.2 7.9 7.0 9.2 6.8 1.1 2.6 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Prok-RING_4 PF14447.6 PXF43997.1 - 5.4 7.0 8.1 11 6.0 8.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Elf1 PF05129.13 PXF43998.1 - 2.4e-29 101.2 0.9 3.2e-29 100.8 0.9 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 PXF43998.1 - 0.0014 17.9 0.2 0.0026 17.1 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Lar_restr_allev PF14354.6 PXF43998.1 - 0.01 16.2 3.0 0.022 15.1 3.0 1.8 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.15 PXF43998.1 - 0.024 14.7 1.8 0.092 12.8 0.5 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Cys_rich_CPXG PF14255.6 PXF43998.1 - 0.042 13.7 2.1 0.083 12.8 1.6 1.9 1 1 0 1 1 1 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.7 PXF43998.1 - 0.047 13.7 1.2 0.088 12.8 1.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rubredoxin PF00301.20 PXF43998.1 - 0.093 12.8 3.0 2.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin UPF0547 PF10571.9 PXF43998.1 - 0.2 11.8 3.0 1.5 9.0 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-H2C2_2 PF13465.6 PXF43998.1 - 0.32 11.5 3.6 9.3 6.9 1.2 2.6 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF43998.1 - 0.56 11.2 2.4 17 6.6 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1642 PF07852.11 PXF43999.1 - 0.1 13.2 0.3 0.23 12.1 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1642) Curto_V3 PF07436.11 PXF43999.1 - 0.77 10.2 3.3 0.57 10.6 0.6 2.1 2 0 0 2 2 2 0 Curtovirus V3 protein DUF1104 PF06518.11 PXF43999.1 - 3.5 8.1 7.2 16 6.0 2.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1104) SAPS PF04499.15 PXF44000.1 - 1.1e-17 64.0 0.5 4.2e-10 39.0 0.0 3.5 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein eIF3_N PF09440.10 PXF44000.1 - 4.2 7.8 0.0 4.2 7.8 0.0 3.2 3 1 1 4 4 4 0 eIF3 subunit 6 N terminal domain BRCA-2_OB1 PF09103.10 PXF44001.1 - 1.2e-14 54.3 0.0 2.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 PXF44001.1 - 5.9e-06 25.9 0.9 0.59 9.9 0.0 4.1 4 0 0 4 4 4 3 BRCA2 repeat O-FucT PF10250.9 PXF44002.1 - 3.6e-12 46.7 0.2 1.5e-11 44.6 0.2 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Mito_carr PF00153.27 PXF44004.1 - 2.4e-32 110.7 1.6 8e-16 57.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med9 PF07544.13 PXF44005.1 - 1.2e-06 28.5 0.9 1.5e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 MCM PF00493.23 PXF44006.1 - 1.5e-98 328.4 0.0 2.2e-98 327.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PXF44006.1 - 1.8e-29 102.1 0.5 3.1e-29 101.4 0.5 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF44006.1 - 1.8e-17 63.5 0.3 4.7e-17 62.2 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PXF44006.1 - 7.7e-10 39.3 0.5 2.5e-09 37.7 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 PXF44006.1 - 1.6e-06 28.1 0.0 8.1e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PXF44006.1 - 3.8e-06 26.4 0.2 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PXF44006.1 - 0.00061 19.7 0.1 0.0018 18.2 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF44006.1 - 0.019 15.4 0.9 0.16 12.4 0.0 2.8 4 0 0 4 4 4 0 AAA ATPase domain RMMBL PF07521.12 PXF44006.1 - 0.04 13.8 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain AAA_lid_2 PF17863.1 PXF44006.1 - 0.051 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA PF00004.29 PXF44006.1 - 0.1 13.0 1.8 1.1 9.7 0.1 3.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 PXF44006.1 - 1.5 9.5 8.8 0.13 13.0 0.8 3.3 4 1 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal Pkinase PF00069.25 PXF44007.1 - 3.5e-48 164.2 0.0 5.3e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44007.1 - 1.7e-23 83.2 0.0 2.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 PXF44007.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mucin PF01456.17 PXF44007.1 - 0.041 13.9 38.7 0.074 13.0 38.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med13_C PF06333.12 PXF44007.1 - 0.046 13.0 7.2 0.068 12.4 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dicty_REP PF05086.12 PXF44007.1 - 0.33 8.9 7.6 0.45 8.4 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIF1 PF05970.14 PXF44008.1 - 1.7e-49 169.0 0.4 3.4e-25 89.0 0.0 3.8 3 1 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 PXF44008.1 - 4.7e-19 68.9 0.0 2.7e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PXF44008.1 - 1e-10 42.1 0.1 6.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 PXF44008.1 - 4.7e-05 22.5 0.1 0.00011 21.2 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PXF44008.1 - 5.6e-05 23.4 0.1 0.00015 22.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF44008.1 - 5.8e-05 23.5 0.1 0.00019 21.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 PXF44008.1 - 0.00017 19.7 0.1 0.0042 15.1 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_5 PF07728.14 PXF44008.1 - 0.00026 21.0 0.1 0.0017 18.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 PXF44008.1 - 0.00045 20.2 0.4 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 NTPase UvrD_C_2 PF13538.6 PXF44008.1 - 0.0034 17.2 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 PXF44008.1 - 0.0041 16.1 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Helicase_RecD PF05127.14 PXF44008.1 - 0.0054 16.6 0.5 0.025 14.4 0.4 2.2 2 1 0 2 2 2 1 Helicase ATPase_2 PF01637.18 PXF44008.1 - 0.017 15.0 0.4 0.11 12.4 0.4 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Presenilin PF01080.17 PXF44008.1 - 0.035 12.9 13.4 0.038 12.7 9.0 2.1 2 0 0 2 2 2 0 Presenilin cobW PF02492.19 PXF44008.1 - 0.043 13.4 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PXF44008.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 PXF44008.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PXF44008.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 PXF44008.1 - 0.11 12.2 3.2 2.5 7.8 0.5 3.6 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PA26 PF04636.13 PXF44008.1 - 0.11 11.4 1.3 0.21 10.5 1.3 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RsgA_GTPase PF03193.16 PXF44008.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SAPS PF04499.15 PXF44008.1 - 4.8 5.9 9.4 0.16 10.8 3.5 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Zip PF02535.22 PXF44008.1 - 8.2 5.5 8.0 9.4 5.3 5.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2975 PF11188.8 PXF44009.1 - 0.015 15.2 1.6 0.68 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) rve PF00665.26 PXF44010.1 - 1e-06 29.0 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HECT PF00632.25 PXF44012.1 - 8.5e-91 304.6 0.0 1.4e-90 303.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 PXF44012.1 - 2.1e-26 90.5 8.2 4.9e-10 38.5 0.0 4.1 3 1 0 3 3 3 3 Ubiquitin binding region RPN5_C PF18098.1 PXF44012.1 - 0.046 13.8 0.1 2.4 8.4 0.0 3.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain RNase_H2-Ydr279 PF09468.10 PXF44012.1 - 0.14 12.4 1.2 0.57 10.3 0.1 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain SMG1_N PF17229.2 PXF44012.1 - 8.9 7.1 10.5 0.59 10.9 2.6 2.8 2 0 0 2 2 2 0 Serine/threonine-protein kinase SMG1 N-terminal zf-Tim10_DDP PF02953.15 PXF44013.1 - 2.4e-11 43.1 4.3 2.8e-11 42.9 4.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PRA1 PF03208.19 PXF44014.1 - 2.7e-31 108.1 0.9 3.2e-31 107.9 0.9 1.1 1 0 0 1 1 1 1 PRA1 family protein OAD_gamma PF04277.13 PXF44014.1 - 1.2 9.8 0.0 1.2 9.8 0.0 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DnaJ_CXXCXGXG PF00684.19 PXF44015.1 - 0.0016 18.8 0.6 0.0027 18.0 0.6 1.3 1 0 0 1 1 1 1 DnaJ central domain zf-TFIIB PF13453.6 PXF44015.1 - 0.024 13.9 2.9 0.28 10.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 PXF44015.1 - 0.025 14.3 1.9 3.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Anti-TRAP PF15777.5 PXF44015.1 - 0.038 14.0 1.8 0.068 13.1 1.8 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein A2L_zn_ribbon PF08792.10 PXF44015.1 - 0.14 11.9 2.2 0.5 10.2 2.3 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain XAF1_C PF18608.1 PXF44015.1 - 0.28 10.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain Met_synt_B12 PF02965.17 PXF44016.1 - 7.2e-107 356.9 0.1 1.6e-106 355.8 0.1 1.6 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 PXF44016.1 - 4.1e-75 253.1 0.0 8.1e-75 252.1 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 PXF44016.1 - 5.6e-54 183.4 0.1 1.2e-52 179.0 0.1 2.3 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 PXF44016.1 - 9.5e-26 90.0 0.1 3.3e-25 88.3 0.1 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 PXF44016.1 - 1.5e-20 73.4 0.3 6.8e-20 71.3 0.3 2.2 1 0 0 1 1 1 1 B12 binding domain Dimer_Tnp_hAT PF05699.14 PXF44017.1 - 5.1e-06 26.2 0.1 1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4734 PF15881.5 PXF44018.1 - 0.0013 18.8 1.2 0.0016 18.6 1.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4734) Citrus_P18 PF05520.11 PXF44019.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Spt20 PF12090.8 PXF44020.1 - 0.022 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Spt20 family NEMO PF11577.8 PXF44022.1 - 0.0027 17.7 1.1 0.0051 16.8 1.1 1.4 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO Imm68 PF15583.6 PXF44022.1 - 0.0065 16.7 0.1 0.0091 16.2 0.1 1.1 1 0 0 1 1 1 1 Immunity protein 68 CCDC24 PF15669.5 PXF44022.1 - 0.011 15.6 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF226 PF02890.14 PXF44022.1 - 0.056 13.5 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Hemagglutinin PF00509.18 PXF44022.1 - 0.19 10.1 0.3 0.24 9.8 0.3 1.1 1 0 0 1 1 1 0 Haemagglutinin APH PF01636.23 PXF44024.1 - 2.5e-08 34.1 0.0 3.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF44024.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 PXF44024.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RST PF12174.8 PXF44024.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DUF5424 PF17462.2 PXF44024.1 - 0.094 12.7 0.0 0.84 9.5 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5424) VWA PF00092.28 PXF44027.1 - 2.8e-17 63.5 0.0 3.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44027.1 - 6.8e-11 42.8 0.0 1.5e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PXF44027.1 - 0.0007 19.0 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein PHO4 PF01384.20 PXF44028.1 - 5.7e-71 239.3 31.0 7.9e-71 238.8 31.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family PsaL PF02605.15 PXF44028.1 - 0.085 12.5 2.8 0.21 11.2 1.1 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI DUF1043 PF06295.12 PXF44028.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) MFS_1 PF07690.16 PXF44029.1 - 6.9e-33 114.0 43.5 1.8e-23 83.1 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PXF44029.1 - 1.2e-32 113.3 19.3 3.9e-29 101.8 6.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 PXF44029.1 - 0.01 14.3 10.7 0.072 11.5 2.4 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MAT1 PF06391.13 PXF44031.1 - 0.17 11.7 0.9 0.37 10.6 0.9 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Lectin_C PF00059.21 PXF44032.1 - 6.3e-14 52.6 0.0 6.3e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain dCache_1 PF02743.18 PXF44032.1 - 1.2e-05 25.3 0.0 0.075 12.8 0.1 2.3 2 0 0 2 2 2 2 Cache domain VWA_2 PF13519.6 PXF44032.1 - 8.5e-05 23.2 0.1 0.00059 20.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF44032.1 - 0.0001 22.3 0.2 0.00018 21.5 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PXF44032.1 - 0.00089 19.5 0.1 0.006 16.9 0.0 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain SKG6 PF08693.10 PXF44032.1 - 0.012 15.0 3.2 0.023 14.1 3.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lectin_C PF00059.21 PXF44034.1 - 1.3e-13 51.6 1.4 1.7e-13 51.2 0.1 2.0 2 0 0 2 2 2 1 Lectin C-type domain VWA_3 PF13768.6 PXF44034.1 - 0.00015 21.8 0.2 0.00029 20.8 0.2 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44034.1 - 0.00015 22.4 0.1 0.00079 20.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain RVT_3 PF13456.6 PXF44034.1 - 0.021 14.6 1.5 0.032 14.1 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like Lyase_8_N PF08124.11 PXF44034.1 - 0.043 12.7 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF4366 PF14283.6 PXF44034.1 - 0.17 11.9 0.0 2.2 8.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) SKG6 PF08693.10 PXF44034.1 - 0.28 10.6 2.7 0.56 9.7 2.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-His_Me_endon PF05551.11 PXF44036.1 - 0.013 15.7 0.5 0.042 14.0 0.5 1.8 1 1 0 1 1 1 0 Zinc-binding loop region of homing endonuclease HTH_23 PF13384.6 PXF44041.1 - 0.00029 20.5 0.2 0.00056 19.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 PXF44041.1 - 0.00041 19.9 0.4 0.00067 19.2 0.4 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 PXF44041.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 PXF44041.1 - 0.0015 18.2 0.2 0.0023 17.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 PXF44041.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain GerE PF00196.19 PXF44041.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_DeoR PF08220.12 PXF44042.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain F420_oxidored PF03807.17 PXF44045.1 - 9.9e-07 29.3 0.1 1.2e-05 25.8 0.1 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 PXF44045.1 - 5.8e-06 26.4 10.3 2.4e-05 24.5 2.5 2.8 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_Gly3P_dh_N PF01210.23 PXF44045.1 - 0.00015 21.8 0.1 0.0064 16.5 0.0 2.3 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 PXF44045.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase 2_5_RNA_ligase2 PF13563.6 PXF44047.1 - 5.9e-21 75.0 0.0 1.4e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 PXF44047.1 - 3.8e-12 46.8 0.1 2e-11 44.5 0.0 2.4 3 0 0 3 3 3 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 PXF44047.1 - 4.8e-06 25.7 0.9 1.4e-05 24.2 0.1 2.0 3 0 0 3 3 3 1 Poly(A) polymerase central domain AKAP7_NLS PF10469.9 PXF44047.1 - 9.2e-05 22.4 0.2 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain PAP_assoc PF03828.19 PXF44047.1 - 0.0099 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase LigT_PEase PF02834.16 PXF44047.1 - 0.11 12.7 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase Pkinase PF00069.25 PXF44048.1 - 6.8e-55 186.3 0.0 9.6e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44048.1 - 8.6e-41 139.9 0.0 1.3e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF44048.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-CHCC PF10276.9 PXF44049.1 - 4.5e-13 49.0 0.8 6.3e-13 48.5 0.8 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 PXF44049.1 - 0.045 13.5 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Zinc Finger domain DUF2730 PF10805.8 PXF44050.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 PXF44050.1 - 0.23 11.6 3.0 0.74 9.9 0.2 2.2 1 1 0 2 2 2 0 TolA binding protein trimerisation APC_N_CC PF16689.5 PXF44050.1 - 0.24 11.5 2.6 3.6 7.7 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Proteasom_Rpn13 PF04683.13 PXF44051.1 - 2.3e-23 82.6 0.0 3.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 PXF44051.1 - 2.2e-19 69.7 1.7 2.2e-19 69.7 1.7 1.7 2 0 0 2 2 2 1 UCH-binding domain GerD PF17898.1 PXF44051.1 - 0.065 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Chloroa_b-bind PF00504.21 PXF44052.1 - 3.2e-36 125.3 0.1 3.9e-36 125.0 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein UQ_con PF00179.26 PXF44053.1 - 3.4e-31 107.8 0.0 4e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF44053.1 - 0.00026 20.7 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 PXF44053.1 - 0.0027 17.4 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_S41 PF03572.18 PXF44054.1 - 1.5e-45 154.7 0.3 2.7e-45 153.9 0.3 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 PXF44054.1 - 9.5e-12 44.6 0.2 2.7e-11 43.1 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PXF44054.1 - 2.3e-08 34.2 0.2 1.1e-07 32.1 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PXF44054.1 - 1.1e-06 28.8 0.1 2.6e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 PXF44054.1 - 0.03 14.4 0.2 0.068 13.2 0.2 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain MFS_1 PF07690.16 PXF44055.1 - 1.8e-16 60.0 49.6 7e-12 44.9 26.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 PXF44055.1 - 4e-09 36.3 10.8 4e-09 36.3 10.8 2.4 3 0 0 3 3 3 1 Nodulin-like Sugar_tr PF00083.24 PXF44055.1 - 0.0013 17.7 15.3 0.0013 17.7 15.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Gar1 PF04410.14 PXF44057.1 - 5e-35 120.5 0.0 6.2e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Mito_carr PF00153.27 PXF44060.1 - 1.2e-52 175.8 2.9 5.7e-21 74.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF44060.1 - 0.038 13.1 2.0 5.1 6.2 0.0 3.2 3 0 0 3 3 3 0 Gammaproteobacterial serine protease zf-met PF12874.7 PXF44062.1 - 4.1e-06 27.0 1.8 4.6e-06 26.8 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PXF44062.1 - 3.9e-05 23.8 0.1 8.1e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 PXF44062.1 - 0.0096 15.7 0.3 0.021 14.6 0.3 1.6 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 PXF44062.1 - 8.2 6.4 6.4 0.46 10.4 0.6 2.0 2 0 0 2 2 2 0 CLIP1 zinc knuckle bZIP_1 PF00170.21 PXF44063.1 - 2.3e-05 24.4 6.2 4.6e-05 23.4 6.2 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PXF44063.1 - 0.0034 17.9 1.7 0.0053 17.3 1.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1465 PF07323.12 PXF44063.1 - 0.0065 16.3 1.1 0.0092 15.8 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) DUF1515 PF07439.11 PXF44063.1 - 0.088 12.8 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) bZIP_2 PF07716.15 PXF44063.1 - 0.2 11.8 7.4 0.32 11.1 7.4 1.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 PXF44064.1 - 0.00025 21.1 9.0 0.00048 20.2 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF44064.1 - 0.00063 19.8 9.1 0.00063 19.8 9.1 1.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF1515 PF07439.11 PXF44064.1 - 0.0097 15.9 0.6 0.017 15.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) SR-25 PF10500.9 PXF44064.1 - 2.7 7.5 10.7 0.71 9.4 0.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CLPTM1 PF05602.12 PXF44065.1 - 3.2e-110 369.1 7.4 4.5e-110 368.6 7.4 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Orf78 PF06024.12 PXF44065.1 - 0.0088 16.3 1.2 0.044 14.1 0.2 2.5 2 0 0 2 2 2 1 Orf78 (ac78) PQ-loop PF04193.14 PXF44065.1 - 0.015 15.0 1.0 0.044 13.5 0.2 2.2 2 0 0 2 2 2 0 PQ loop repeat DUF2615 PF11027.8 PXF44065.1 - 0.068 13.3 1.3 0.8 9.9 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) 2TM PF13239.6 PXF44065.1 - 5.2 7.5 8.1 21 5.5 2.7 2.8 2 0 0 2 2 2 0 2TM domain TIP41 PF04176.13 PXF44066.1 - 4.9e-47 159.6 0.1 6.7e-47 159.2 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family tRNA-synt_1c PF00749.21 PXF44068.1 - 1.1e-101 339.9 0.0 1.4e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L26 PF16906.5 PXF44069.1 - 1.6e-39 134.2 3.5 2.2e-39 133.8 3.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 PXF44069.1 - 0.0055 16.6 4.4 0.0063 16.4 1.9 2.3 2 1 0 2 2 2 1 KOW motif DUF4121 PF13497.6 PXF44069.1 - 0.021 14.0 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) EF-hand_1 PF00036.32 PXF44070.1 - 6.6e-09 34.7 0.0 0.00072 18.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PXF44070.1 - 4.4e-08 33.5 0.0 2.3e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PXF44070.1 - 1.2e-06 28.2 0.0 2.8e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PXF44070.1 - 4.4e-06 25.9 0.0 0.0041 16.5 0.0 2.6 2 0 0 2 2 2 2 EF hand C2 PF00168.30 PXF44070.1 - 3.3e-05 24.1 0.0 6.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 PXF44070.1 - 4e-05 23.2 0.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain Glycos_transf_2 PF00535.26 PXF44072.1 - 1.5e-10 41.1 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF44072.1 - 0.00023 21.1 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 PXF44072.1 - 0.00035 20.3 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family Glyco_trans_2_3 PF13632.6 PXF44072.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Thioredoxin PF00085.20 PXF44073.1 - 1.6e-26 92.3 0.0 2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF44073.1 - 3.1e-07 30.8 0.2 3.3e-06 27.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF44073.1 - 0.00036 20.7 0.0 0.00074 19.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PXF44073.1 - 0.001 19.3 0.0 0.0034 17.7 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF44073.1 - 0.0031 17.4 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PXF44073.1 - 0.0046 16.7 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 PXF44073.1 - 0.037 13.9 0.0 0.047 13.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 PXF44073.1 - 0.089 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein RLL PF10036.9 PXF44074.1 - 1.7e-35 123.1 0.8 8.9e-35 120.8 0.8 1.8 1 1 0 1 1 1 1 RNA transcription, translation and transport factor protein Tam41_Mmp37 PF09139.11 PXF44075.1 - 3.6e-80 269.8 0.0 5.1e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Pkinase PF00069.25 PXF44076.1 - 1.5e-68 231.0 0.0 1.8e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44076.1 - 1.2e-28 100.1 0.0 1.5e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF44076.1 - 0.0079 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF44076.1 - 0.044 12.7 0.0 0.073 12.0 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PXF44076.1 - 0.058 13.3 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 PXF44077.1 - 7.5e-18 63.9 34.7 6.8e-05 23.1 1.7 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF44077.1 - 4.3e-14 52.2 35.8 0.00035 20.9 3.2 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF44077.1 - 1.5e-13 50.3 32.3 0.00096 19.8 1.2 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF44077.1 - 4.7e-05 24.1 12.6 0.52 11.0 12.5 4.5 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PXF44077.1 - 5.8e-05 23.3 17.9 0.18 12.1 0.7 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 PXF44077.1 - 0.00022 21.5 16.9 0.045 14.1 3.0 3.2 1 1 2 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PXF44077.1 - 0.0011 18.9 26.2 0.0029 17.5 0.9 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 PXF44077.1 - 0.0012 19.1 19.6 0.94 10.0 0.3 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 PXF44077.1 - 0.033 14.6 17.0 0.53 10.8 0.3 4.4 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 PXF44077.1 - 0.07 12.9 30.4 0.18 11.6 0.4 5.9 6 0 0 6 6 6 0 C2H2-type zinc-finger domain PhnA_Zn_Ribbon PF08274.12 PXF44077.1 - 0.092 12.7 4.9 37 4.4 0.1 3.7 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Yippee-Mis18 PF03226.14 PXF44077.1 - 0.4 10.9 9.8 0.24 11.6 2.1 3.1 2 2 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_15 PF17032.5 PXF44077.1 - 0.41 11.4 15.2 0.29 11.9 1.2 3.0 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_9 PF16293.5 PXF44077.1 - 0.58 10.0 8.0 2.4 8.1 0.5 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 PXF44077.1 - 0.63 9.1 17.5 21 4.2 5.0 4.2 1 1 2 3 3 3 0 Putative actin-like family FYDLN_acid PF09538.10 PXF44077.1 - 1 10.1 3.6 96 3.7 0.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (FYDLN_acid) zf_UBZ PF18439.1 PXF44077.1 - 1.2 8.8 12.8 0.71 9.5 0.2 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger SR-25 PF10500.9 PXF44077.1 - 1.3 8.5 6.4 3.4 7.2 6.4 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2_2 PF12756.7 PXF44077.1 - 3.3 8.1 19.2 6.1 7.2 0.6 4.2 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) HSP90 PF00183.18 PXF44078.1 - 8.2e-230 764.1 33.3 1.1e-229 763.7 33.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PXF44078.1 - 3.1e-12 47.0 0.2 6.4e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PXF44078.1 - 8.5e-10 38.6 0.7 8.5e-10 38.6 0.7 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 PXF44078.1 - 0.039 14.0 0.2 0.22 11.6 0.1 2.3 2 0 0 2 2 2 0 Tumour suppressor protein FAR1 PF03101.15 PXF44078.1 - 0.045 14.4 0.6 0.15 12.8 0.6 1.9 1 0 0 1 1 1 0 FAR1 DNA-binding domain UDPGT PF00201.18 PXF44078.1 - 0.12 11.2 1.1 0.25 10.1 1.1 1.5 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Brr6_like_C_C PF10104.9 PXF44079.1 - 5.3e-21 74.8 1.2 7.4e-21 74.3 1.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DSPc PF00782.20 PXF44081.1 - 5.9e-05 22.9 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PXF44081.1 - 0.00056 19.5 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PXF44081.1 - 0.0009 19.4 0.5 0.0018 18.4 0.0 1.8 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PXF44081.1 - 0.012 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 PXF44081.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF2532 PF10811.8 PXF44082.1 - 0.08 13.0 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) NPIP PF06409.11 PXF44082.1 - 0.45 9.5 3.1 0.74 8.8 3.1 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Mannitol_dh_C PF08125.13 PXF44083.1 - 2.7e-80 269.4 0.0 3.8e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 PXF44083.1 - 4.5e-41 140.5 0.0 6.6e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain DUF21 PF01595.20 PXF44084.1 - 1.3e-33 116.1 0.5 3.1e-33 115.0 0.5 1.6 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PXF44084.1 - 5.2e-08 33.2 0.5 0.008 16.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 PXF44084.1 - 0.0032 17.5 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Histidinol_dh PF00815.20 PXF44085.1 - 1.1e-142 475.9 1.2 1.3e-142 475.6 1.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.21 PXF44086.1 - 4e-16 59.1 0.0 3.7e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II DOPA_dioxygen PF08883.11 PXF44086.1 - 0.031 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family PGM_PMM_I PF02878.16 PXF44087.1 - 1.6e-22 79.7 2.1 3.7e-10 39.6 0.3 3.7 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 PXF44087.1 - 1.1e-08 35.1 0.2 4.2e-08 33.3 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 PXF44087.1 - 1.8e-06 28.5 0.0 1e-05 26.1 0.0 2.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PXF44087.1 - 3.7e-05 23.9 0.2 0.0004 20.5 0.2 2.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III UPF0146 PF03686.13 PXF44087.1 - 0.12 12.3 0.1 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) SelP_N PF04592.14 PXF44087.1 - 0.2 11.0 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pantoate_transf PF02548.15 PXF44088.1 - 3.1e-99 331.6 3.2 3.6e-99 331.4 3.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 PXF44088.1 - 9.3e-05 22.0 7.1 0.0002 20.9 7.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NanE PF04131.14 PXF44088.1 - 0.022 14.0 2.4 0.18 11.0 0.1 2.8 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase mTERF PF02536.14 PXF44089.1 - 1.2e-38 132.9 0.0 4.9e-15 55.3 0.0 3.1 1 1 2 3 3 3 3 mTERF EF-hand_6 PF13405.6 PXF44090.1 - 7.9e-05 22.3 0.0 0.00026 20.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 PXF44090.1 - 0.00029 20.2 0.0 0.0012 18.2 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PXF44090.1 - 0.004 17.6 0.1 0.012 16.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PXF44090.1 - 0.0077 15.7 0.2 0.28 10.8 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PXF44090.1 - 0.015 15.1 0.0 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair RIIa PF02197.17 PXF44090.1 - 0.094 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Beach PF02138.18 PXF44091.1 - 1.8e-96 322.8 0.0 3.1e-96 322.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 PXF44091.1 - 0.0025 17.9 1.0 3.8 7.7 0.1 3.9 3 1 0 3 3 3 2 PH domain associated with Beige/BEACH GRAM PF02893.20 PXF44091.1 - 0.0033 17.3 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 GRAM domain WD40 PF00400.32 PXF44091.1 - 0.021 15.7 0.1 2 9.4 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat BBS2_Mid PF14783.6 PXF44091.1 - 0.051 13.6 0.0 0.27 11.3 0.0 2.2 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PsbP PF01789.16 PXF44094.1 - 2.6e-29 102.4 0.0 3.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 PsbP LcrG PF07216.12 PXF44094.1 - 0.048 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 LcrG protein DUF543 PF04418.12 PXF44095.1 - 2.8e-16 59.3 0.7 3.2e-16 59.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Na_H_antiport_2 PF13726.6 PXF44095.1 - 0.043 13.9 2.2 0.06 13.5 2.2 1.2 1 0 0 1 1 1 0 Na+-H+ antiporter family Yae1_N PF09811.9 PXF44096.1 - 0.004 16.8 2.3 0.0082 15.8 2.2 1.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal CDI PF02234.19 PXF44097.1 - 8.6e-06 25.9 0.1 1.3e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor Aha1_N PF09229.11 PXF44098.1 - 1.7e-17 63.9 0.1 3.7e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 PXF44098.1 - 1.3e-10 41.5 0.3 2.2e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein CS PF04969.16 PXF44099.1 - 2.2e-08 35.0 0.0 4.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 CS domain RIO1 PF01163.22 PXF44100.1 - 4.4e-16 59.0 0.0 6.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PXF44100.1 - 8e-15 55.4 0.9 2.9e-06 27.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF44100.1 - 1.8e-12 47.1 0.0 2.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PXF44100.1 - 2e-12 47.0 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44100.1 - 3.2e-08 33.2 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 PXF44100.1 - 3.7e-06 26.7 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 PXF44100.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 PXF44100.1 - 0.064 12.6 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase phage_tail_N PF08400.10 PXF44100.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal SKI PF01202.22 PXF44101.1 - 2.8e-43 147.8 0.0 4e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 PXF44101.1 - 3.9e-07 30.7 0.0 1.1e-06 29.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PXF44101.1 - 6.2e-07 29.7 0.0 1.1e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 PXF44101.1 - 0.00037 20.7 0.1 0.00089 19.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 PXF44101.1 - 0.00054 19.8 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 PXF44101.1 - 0.00065 20.1 0.0 0.043 14.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PXF44101.1 - 0.014 15.8 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 PXF44101.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 PXF44101.1 - 0.038 14.3 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PXF44101.1 - 0.04 13.9 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PXF44101.1 - 0.04 13.6 0.0 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 PXF44101.1 - 0.082 13.3 0.1 0.34 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ADK PF00406.22 PXF44101.1 - 0.098 12.8 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase RsgA_GTPase PF03193.16 PXF44101.1 - 0.14 12.0 0.1 0.34 10.8 0.1 1.5 1 1 0 1 1 1 0 RsgA GTPase RRM_1 PF00076.22 PXF44103.1 - 2.9e-18 65.4 0.0 4.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 PXF44105.1 - 6.2e-20 71.1 0.0 9e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FrhB_FdhB_N PF04422.13 PXF44105.1 - 0.067 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Nop PF01798.18 PXF44106.1 - 2.3e-87 292.3 0.1 2.3e-87 292.3 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PXF44106.1 - 3.5e-17 62.5 0.4 3.5e-17 62.5 0.4 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Macoilin PF09726.9 PXF44106.1 - 2 6.9 22.8 3 6.3 22.8 1.2 1 0 0 1 1 1 0 Macoilin family GAGA_bind PF06217.12 PXF44106.1 - 5.5 7.2 18.7 14 5.8 18.7 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family zf-CW PF07496.15 PXF44107.1 - 0.00057 19.8 1.8 0.00057 19.8 1.8 2.2 2 0 0 2 2 2 1 CW-type Zinc Finger PHD PF00628.29 PXF44107.1 - 0.001 18.9 7.8 0.001 18.9 7.8 2.2 2 0 0 2 2 2 1 PHD-finger PBP1_TM PF14812.6 PXF44107.1 - 0.034 14.5 0.8 0.1 13.0 0.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD_2 PF13831.6 PXF44107.1 - 0.2 11.2 4.9 0.56 9.8 4.9 1.8 1 0 0 1 1 1 0 PHD-finger Fer4 PF00037.27 PXF44108.1 - 4.2e-15 54.8 17.8 5.4e-09 35.5 5.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 PXF44108.1 - 6.3e-14 52.3 11.2 1e-13 51.6 11.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PXF44108.1 - 5.1e-11 42.5 22.9 1e-07 31.9 13.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 PXF44108.1 - 5.5e-11 43.3 7.5 2.2e-05 25.3 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 PXF44108.1 - 3.7e-10 39.8 10.5 6e-10 39.1 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 PXF44108.1 - 8.1e-10 38.7 5.4 7.2e-05 22.8 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 PXF44108.1 - 9.6e-08 32.4 20.1 1.7e-05 25.1 11.5 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 PXF44108.1 - 1.4e-07 31.3 18.2 0.00019 21.3 5.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 PXF44108.1 - 1.5e-06 28.0 13.0 0.0026 17.7 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 PXF44108.1 - 1.6e-05 25.0 12.4 0.0011 19.3 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 PXF44108.1 - 0.0001 22.8 12.0 0.0068 16.9 12.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 PXF44108.1 - 0.00095 19.9 18.5 0.0041 17.9 5.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 PXF44108.1 - 0.001 19.6 12.2 0.062 13.8 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 PXF44108.1 - 0.017 15.3 5.5 0.61 10.4 0.4 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 PXF44108.1 - 0.063 13.5 10.3 5.1 7.3 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 PXF44108.1 - 0.29 11.3 6.6 2 8.6 0.7 2.4 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 PXF44108.1 - 0.44 10.6 6.3 0.39 10.8 1.3 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 PXF44108.1 - 0.73 10.7 12.9 2.1 9.3 2.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-ribbon_3 PF13248.6 PXF44109.1 - 0.073 12.5 1.6 0.2 11.1 1.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 PXF44109.1 - 0.18 11.9 0.9 0.48 10.5 0.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon PRP38 PF03371.15 PXF44110.1 - 4.2e-44 150.5 0.0 5e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 PRP38 family RNA_pol_3_Rpc31 PF11705.8 PXF44111.1 - 0.21 11.8 10.2 0.24 11.7 10.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 PXF44111.1 - 1.7 6.7 6.5 1.9 6.6 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family Nic96 PF04097.14 PXF44112.1 - 3.8e-85 286.6 0.0 5.4e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 zf-RING_2 PF13639.6 PXF44113.1 - 7e-08 32.7 14.4 1.4e-07 31.7 14.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PXF44113.1 - 2.8e-05 23.9 9.5 5.5e-05 23.0 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF44113.1 - 4.7e-05 23.3 7.9 9.3e-05 22.4 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF44113.1 - 6.7e-05 22.7 11.0 0.00012 21.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF44113.1 - 0.0029 17.3 6.9 0.0061 16.3 6.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF44113.1 - 0.0075 16.5 10.6 0.032 14.5 10.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF44113.1 - 0.036 14.0 12.6 0.062 13.3 12.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PXF44113.1 - 0.039 13.8 12.7 0.074 12.9 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF44113.1 - 0.058 13.3 8.7 0.12 12.2 8.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GAS PF13851.6 PXF44113.1 - 0.23 10.8 5.5 0.37 10.1 5.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-C3HC4_4 PF15227.6 PXF44113.1 - 0.3 11.3 10.2 0.52 10.5 7.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PXF44113.1 - 0.61 10.0 5.1 1.3 9.0 5.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PXF44113.1 - 0.67 10.0 6.9 1.8 8.7 6.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PXF44113.1 - 2 8.6 8.8 4.8 7.4 8.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Methyltransf_21 PF05050.12 PXF44114.1 - 2.2e-10 40.8 0.0 3.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain RNase_PH PF01138.21 PXF44115.1 - 2.3e-14 54.0 0.2 5.1e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF44115.1 - 2.1e-07 30.8 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NTP_transf_3 PF12804.7 PXF44116.1 - 2.3e-13 50.8 0.0 2.9e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 PXF44116.1 - 1.9e-06 27.6 0.0 8e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase IspD PF01128.19 PXF44116.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2-Hacid_dh_C PF02826.19 PXF44119.1 - 1.4e-60 203.7 0.0 1.9e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PXF44119.1 - 8.5e-31 106.4 0.0 9.7e-31 106.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 PXF44119.1 - 9.7e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 PXF44119.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 PXF44119.1 - 0.001 19.2 0.0 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PXF44119.1 - 0.0015 19.0 0.0 0.0045 17.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 PXF44119.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 PXF44119.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 PXF44119.1 - 0.05 14.1 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Aminotran_1_2 PF00155.21 PXF44120.1 - 3.3e-52 177.8 0.0 3.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PXF44120.1 - 0.00022 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF44120.1 - 0.012 14.1 0.0 0.025 13.1 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PXF44120.1 - 0.11 11.5 0.0 1.6 7.6 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V RRM_1 PF00076.22 PXF44121.1 - 7.2e-13 48.2 0.0 1.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 PXF44122.1 - 1.9e-21 76.7 2.1 3e-21 76.1 2.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 PXF44122.1 - 3.5e-18 65.2 0.0 6.4e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PXF44122.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif CDC45 PF02724.14 PXF44125.1 - 0.03 12.6 4.5 0.04 12.2 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Oxysterol_BP PF01237.18 PXF44125.1 - 0.076 11.8 4.3 0.08 11.8 4.3 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein U79_P34 PF03064.16 PXF44125.1 - 0.086 12.2 13.0 0.12 11.7 13.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 PXF44125.1 - 0.093 11.5 1.5 0.079 11.7 1.5 1.1 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 PXF44125.1 - 0.12 12.0 7.8 0.15 11.6 7.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Ycf1 PF05758.12 PXF44125.1 - 0.13 10.1 5.4 0.16 9.8 5.4 1.0 1 0 0 1 1 1 0 Ycf1 LPD30 PF18850.1 PXF44125.1 - 0.15 11.9 0.5 0.25 11.1 0.5 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 DUF3408 PF11888.8 PXF44125.1 - 0.25 11.5 10.5 0.41 10.8 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CCDC66 PF15236.6 PXF44125.1 - 0.72 9.7 24.1 1.1 9.1 24.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DREPP PF05558.12 PXF44125.1 - 0.96 9.3 6.8 1.3 8.9 6.8 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF1682 PF07946.14 PXF44125.1 - 1.3 8.2 10.0 1.7 7.8 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 PXF44125.1 - 1.6 8.4 7.2 2.3 7.9 7.2 1.1 1 0 0 1 1 1 0 Connexin Afi1 PF07792.12 PXF44125.1 - 2 8.9 6.6 0.6 10.6 3.5 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Casc1_N PF15927.5 PXF44125.1 - 5.3 6.7 23.3 9.4 5.9 23.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus BT1 PF03092.16 PXF44125.1 - 9 4.4 5.4 11 4.1 5.4 1.1 1 0 0 1 1 1 0 BT1 family Aldo_ket_red PF00248.21 PXF44127.1 - 3.3e-46 157.8 0.0 3.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PXF44128.1 - 5.6e-36 124.2 0.0 6.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_5 PF07878.11 PXF44128.1 - 0.041 13.8 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 PBS_linker_poly PF00427.21 PXF44129.1 - 1.6e-32 112.2 0.3 2.4e-32 111.6 0.3 1.3 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide CpcD PF01383.21 PXF44129.1 - 1.2e-15 57.5 2.8 5.9e-12 45.7 0.0 2.7 3 0 0 3 3 3 2 CpcD/allophycocyanin linker domain zf-RING_13 PF17977.1 PXF44129.1 - 0.075 13.2 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CCB2_CCB4 PF11152.8 PXF44130.1 - 4.5e-27 94.7 0.1 9.8e-27 93.5 0.1 1.5 1 1 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 GAF_2 PF13185.6 PXF44130.1 - 0.0058 16.9 0.0 0.0086 16.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain Cupin_4 PF08007.12 PXF44131.1 - 3.5e-51 174.6 0.0 4.5e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 PXF44131.1 - 5.8e-10 39.3 0.0 3.1e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 PXF44131.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Castor_Poll_mid PF06241.12 PXF44132.1 - 5.4e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 PXF44132.1 - 0.0014 18.4 0.0 0.019 14.8 0.0 2.9 3 0 0 3 3 3 1 TrkA-C domain zf-C2H2 PF00096.26 PXF44133.1 - 1.5e-31 107.1 31.6 7.2e-06 26.2 0.2 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF44133.1 - 4.3e-28 96.5 30.1 8e-07 29.2 0.1 6.5 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF44133.1 - 6.6e-18 63.9 40.3 0.002 18.8 0.2 6.6 7 0 0 7 7 6 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF44133.1 - 2e-08 33.8 19.7 0.0022 17.7 0.0 6.1 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PXF44133.1 - 3.8e-06 27.0 14.4 0.22 11.8 0.8 6.0 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 PXF44133.1 - 3.2e-05 24.1 16.7 8.1e-05 22.9 2.3 3.4 1 1 3 4 4 4 1 C2H2-type zinc ribbon TRAF6_Z2 PF18048.1 PXF44133.1 - 4.7e-05 23.4 6.6 1.6 8.9 0.0 4.7 4 1 0 4 4 4 2 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_5 PF13909.6 PXF44133.1 - 6.8e-05 22.5 35.4 0.31 10.9 0.6 6.9 7 2 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 PXF44133.1 - 0.0038 17.9 14.7 0.047 14.4 2.2 4.5 1 1 2 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 PXF44133.1 - 0.014 15.0 0.6 0.014 15.0 0.6 3.7 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 PXF44133.1 - 0.02 15.5 12.3 0.77 10.4 0.2 4.8 2 1 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_7 PF15269.6 PXF44133.1 - 0.032 14.3 0.9 0.032 14.3 0.9 5.3 3 2 3 6 6 6 0 Zinc-finger ADK_lid PF05191.14 PXF44133.1 - 0.074 13.1 5.3 2.9 8.0 0.0 3.8 2 2 0 2 2 2 0 Adenylate kinase, active site lid GAGA PF09237.11 PXF44133.1 - 0.099 12.5 7.6 0.97 9.3 0.1 3.5 2 1 2 4 4 4 0 GAGA factor zf-met PF12874.7 PXF44133.1 - 0.1 13.0 20.8 3.4 8.2 0.0 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 PXF44133.1 - 0.42 9.7 5.7 19 4.3 5.7 2.4 1 1 0 1 1 1 0 Putative actin-like family IBR PF01485.21 PXF44133.1 - 0.5 10.6 17.4 16 5.8 6.3 3.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf_Hakai PF18408.1 PXF44133.1 - 0.67 9.7 0.0 0.67 9.7 0.0 3.8 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain CDP-OH_P_transf PF01066.21 PXF44134.1 - 1.6e-18 67.2 0.1 1.6e-18 67.2 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DHFR_1 PF00186.19 PXF44135.1 - 2.2e-32 112.0 0.0 4.8e-32 110.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase AIRS_C PF02769.22 PXF44136.1 - 3.3e-25 89.0 0.1 1.5e-24 86.9 0.0 2.1 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 PXF44136.1 - 5.8e-16 58.9 0.5 1.4e-15 57.7 0.3 1.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Mitoc_mL59 PF18126.1 PXF44137.1 - 2.7e-05 24.5 11.1 6.5e-05 23.3 2.1 2.6 2 1 1 3 3 3 2 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 PXF44137.1 - 0.00011 22.0 7.7 0.00011 22.0 7.7 1.4 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SPT16 PF08644.11 PXF44137.1 - 0.2 11.8 3.2 0.2 11.8 2.5 1.3 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) UQ_con PF00179.26 PXF44138.1 - 6.4e-41 139.3 0.0 7.9e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF44138.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PXF44138.1 - 0.0014 18.9 0.0 0.0018 18.6 0.0 1.3 1 1 0 1 1 1 1 RWD domain KTI12 PF08433.10 PXF44139.1 - 1.4e-66 224.8 0.5 4.3e-66 223.1 0.5 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PXF44139.1 - 1.1e-11 45.1 0.5 4e-11 43.3 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF44139.1 - 0.00042 20.9 0.0 0.00095 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PXF44139.1 - 0.0026 17.7 0.7 0.21 11.5 0.0 2.2 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.6 PXF44139.1 - 0.012 16.0 0.2 0.017 15.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 PXF44139.1 - 0.031 13.3 0.0 0.07 12.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 PXF44139.1 - 0.033 14.3 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 PXF44139.1 - 0.055 13.2 0.0 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 PXF44139.1 - 0.059 13.1 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 PXF44139.1 - 0.13 12.5 0.1 0.55 10.5 0.0 2.0 3 0 0 3 3 3 0 AAA domain ORC5_C PF14630.6 PXF44140.1 - 1.3e-49 169.3 0.2 1.7e-49 168.9 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus peroxidase PF00141.23 PXF44141.1 - 5.1e-47 160.5 0.0 9.9e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase RskA PF10099.9 PXF44141.1 - 0.39 11.0 8.4 0.63 10.3 8.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DOMON PF03351.17 PXF44142.1 - 1.1e-32 112.9 0.2 7.6e-19 68.2 0.0 2.5 2 0 0 2 2 2 2 DOMON domain DM13 PF10517.9 PXF44142.1 - 1.1e-19 71.0 0.0 2.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Electron transfer DM13 Cytochrom_B561 PF03188.16 PXF44142.1 - 8.6e-06 25.9 8.8 1.4e-05 25.2 8.8 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 TGBp3 PF02495.17 PXF44142.1 - 0.0067 16.1 0.3 0.0067 16.1 0.3 2.4 2 0 0 2 2 2 1 Triple gene block 3 DUF2427 PF10348.9 PXF44142.1 - 0.033 14.0 1.3 0.082 12.7 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Rbx_binding PF18113.1 PXF44142.1 - 0.11 12.3 0.0 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin binding C-terminal domain Wzy_C PF04932.15 PXF44142.1 - 2.1 8.0 5.5 1.6 8.3 3.0 1.9 1 1 1 2 2 2 0 O-Antigen ligase DUF4079 PF13301.6 PXF44142.1 - 5.8 7.1 9.0 37 4.5 9.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF998 PF06197.13 PXF44142.1 - 6.2 6.4 16.1 4.5 6.8 9.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3228 PF11539.8 PXF44144.1 - 8e-77 257.2 0.0 1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) ArfGap PF01412.18 PXF44146.1 - 4.6e-33 113.8 1.2 7.2e-33 113.1 0.5 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Glyco_transf_20 PF00982.21 PXF44147.1 - 2.1e-132 442.2 0.0 3.8e-132 441.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PXF44147.1 - 1.3e-37 129.2 0.0 9.4e-29 100.2 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 PXF44147.1 - 0.00076 19.3 0.0 0.65 9.7 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_trans_1_2 PF13524.6 PXF44147.1 - 0.022 15.2 1.5 0.13 12.7 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferases group 1 LcrG PF07216.12 PXF44147.1 - 0.31 11.0 1.3 0.91 9.5 1.3 1.7 1 0 0 1 1 1 0 LcrG protein GTP_EFTU PF00009.27 PXF44149.1 - 1.3e-47 161.9 0.0 2e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PXF44149.1 - 7.3e-46 154.7 0.3 1.2e-45 154.0 0.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PXF44149.1 - 8.6e-18 64.2 0.0 2.2e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF44149.1 - 4.3e-07 30.2 0.0 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF44149.1 - 4.4e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 PXF44149.1 - 0.0032 17.5 0.0 0.011 15.9 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 PXF44149.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PXF44149.1 - 0.021 14.5 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RF3_C PF16658.5 PXF44149.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain FeoB_N PF02421.18 PXF44149.1 - 0.045 13.3 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PXF44149.1 - 0.08 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Asp PF00026.23 PXF44151.1 - 6.4e-27 94.8 0.0 7.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 PXF44151.1 - 0.0021 17.8 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PXF44151.1 - 0.0043 17.3 0.0 0.0043 17.3 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal P2X_receptor PF00864.19 PXF44151.1 - 0.11 11.6 2.0 0.13 11.3 1.0 1.5 2 0 0 2 2 2 0 ATP P2X receptor DUF4690 PF15756.5 PXF44151.1 - 0.94 10.1 2.8 0.59 10.8 0.5 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DEAD PF00270.29 PXF44152.1 - 2.5e-35 121.8 0.0 3.6e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF44152.1 - 1e-25 90.2 0.0 6.3e-25 87.7 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF44152.1 - 9.4e-06 25.7 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PXF44152.1 - 0.0084 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF44152.1 - 0.071 13.4 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 PXF44152.1 - 0.078 12.3 0.1 0.078 12.3 0.1 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit VWA PF00092.28 PXF44153.1 - 9.8e-23 81.3 0.1 1.3e-22 80.9 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44153.1 - 2.5e-12 47.4 0.0 4.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF44153.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF1194 PF06707.11 PXF44153.1 - 0.15 11.3 0.1 2.4 7.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) FWWh PF14922.6 PXF44155.1 - 0.039 13.9 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function Cep57_CLD PF14073.6 PXF44155.1 - 0.097 12.7 0.2 0.13 12.2 0.2 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 SHOCT PF09851.9 PXF44156.1 - 0.0097 15.6 1.0 0.019 14.7 0.0 2.1 3 0 0 3 3 3 1 Short C-terminal domain DUF948 PF06103.11 PXF44156.1 - 0.04 14.2 0.2 0.073 13.3 0.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TAFH PF07531.14 PXF44156.1 - 0.052 13.7 0.2 0.11 12.6 0.1 1.6 2 0 0 2 2 2 0 NHR1 homology to TAF Methyltransf_21 PF05050.12 PXF44158.1 - 6.5e-16 58.8 0.0 9.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Yip1 PF04893.17 PXF44158.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Retrotrans_gag PF03732.17 PXF44159.1 - 2.3e-05 24.5 0.4 5.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein CASP_C PF08172.12 PXF44159.1 - 0.0055 16.1 1.4 0.0059 16.0 1.4 1.2 1 1 0 1 1 1 1 CASP C terminal Phage_GPO PF05929.11 PXF44159.1 - 0.029 14.0 0.8 0.054 13.1 0.8 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Lzipper-MIP1 PF14389.6 PXF44159.1 - 0.033 14.5 2.8 0.042 14.1 1.0 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 NPV_P10 PF05531.12 PXF44159.1 - 0.1 13.0 1.3 0.14 12.6 0.7 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HTH_Tnp_Mu_2 PF09039.11 PXF44160.1 - 0.027 14.5 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Ku_N PF03731.15 PXF44160.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Cyclin PF08613.11 PXF44161.1 - 4.1e-29 102.0 0.0 6.1e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF44161.1 - 1.1e-07 31.6 0.2 2.1e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3198 PF11433.8 PXF44161.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Amidohydro_3 PF07969.11 PXF44162.1 - 2.3e-67 228.5 0.0 2.9e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PXF44162.1 - 5e-13 49.1 0.0 8.5e-11 41.7 0.0 3.0 3 1 0 3 3 3 2 Amidohydrolase family DUF2100 PF09873.9 PXF44162.1 - 0.0062 16.4 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2100) SMC_ScpB PF04079.16 PXF44165.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB PLD_C PF12357.8 PXF44167.1 - 2.6e-18 65.7 0.0 4.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase D C terminal C2 PF00168.30 PXF44167.1 - 2e-09 37.7 0.0 3.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain PLDc PF00614.22 PXF44167.1 - 1.7e-08 34.3 0.0 0.00015 21.8 0.0 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PXF44167.1 - 7.9e-06 25.8 0.0 0.00031 20.6 0.0 2.9 3 0 0 3 3 3 1 PLD-like domain SHOCT PF09851.9 PXF44170.1 - 0.011 15.5 0.6 0.03 14.1 0.0 2.2 2 0 0 2 2 2 0 Short C-terminal domain DUF3767 PF12597.8 PXF44170.1 - 0.077 12.8 0.0 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3767) Ank_2 PF12796.7 PXF44172.1 - 4.8e-59 196.9 14.2 1.4e-15 57.6 0.1 6.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF44172.1 - 1.9e-42 143.1 11.4 1.5e-10 41.4 0.1 9.0 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 PXF44172.1 - 3.5e-38 128.4 25.0 2.1e-06 27.9 0.1 10.5 10 0 0 10 10 9 6 Ankyrin repeat Ank_3 PF13606.6 PXF44172.1 - 4.4e-37 121.9 8.1 5.8e-06 26.3 0.1 11.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PXF44172.1 - 9.6e-36 121.4 10.7 1.9e-07 31.2 0.0 8.8 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Arm PF00514.23 PXF44172.1 - 1.4e-27 94.8 15.3 1.1e-08 34.9 0.1 6.4 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PXF44172.1 - 3.9e-05 24.0 0.1 3.9e-05 24.0 0.1 6.2 7 1 1 8 8 7 1 HEAT repeats Arm_3 PF16186.5 PXF44172.1 - 6.7e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Atypical Arm repeat Arm_2 PF04826.13 PXF44172.1 - 0.00031 20.3 0.0 0.0012 18.4 0.0 1.9 1 1 1 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 PXF44172.1 - 0.00075 19.9 0.2 0.00075 19.9 0.2 3.8 4 1 1 5 5 4 1 HEAT-like repeat Cnd3 PF12719.7 PXF44172.1 - 0.012 14.8 0.2 0.14 11.3 0.1 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Ribosomal_L41 PF05162.13 PXF44172.1 - 0.3 11.2 2.2 1 9.5 2.2 1.9 1 0 0 1 1 1 0 Ribosomal protein L41 HEAT PF02985.22 PXF44172.1 - 0.62 10.5 5.7 8.7 6.9 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat SRF-TF PF00319.18 PXF44173.1 - 0.00055 19.4 0.2 0.00088 18.7 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TraY PF05509.11 PXF44176.1 - 0.057 13.5 0.5 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 TraY domain JAB PF01398.21 PXF44177.1 - 1.1e-32 112.5 0.0 2.3e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PXF44177.1 - 5.7e-14 52.5 1.5 5.7e-14 52.5 1.5 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 PXF44177.1 - 9e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PXF44177.1 - 0.028 14.5 0.4 0.1 12.6 0.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF5624 PF18538.1 PXF44177.1 - 0.035 14.2 0.2 0.065 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) GDPD PF03009.17 PXF44178.1 - 4.1e-20 72.6 0.0 5.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ODV-E18 PF10717.9 PXF44178.1 - 0.38 10.7 1.6 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 AA_permease_2 PF13520.6 PXF44181.1 - 4.7e-43 147.6 41.1 9.6e-43 146.6 39.6 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PXF44181.1 - 7.6e-29 100.6 33.9 1.2e-28 99.9 33.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 PXF44181.1 - 1.6e-10 40.9 1.7 1.6e-10 40.9 1.7 3.6 2 1 0 2 2 2 1 C-terminus of AA_permease DUF2101 PF09874.9 PXF44181.1 - 0.01 15.6 2.1 0.02 14.6 2.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2101) DUF3043 PF11241.8 PXF44181.1 - 1.4 8.9 7.3 1.5 8.8 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) TssN PF17555.2 PXF44181.1 - 1.9 7.8 12.3 0.63 9.4 0.7 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN Sigma_reg_N PF13800.6 PXF44181.1 - 2.6 8.4 4.4 1.2 9.4 0.5 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2417 PF10329.9 PXF44181.1 - 10 5.5 7.5 5.7 6.3 0.8 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Ecm29 PF13001.7 PXF44182.1 - 2.8e-56 191.2 0.3 3.7e-53 180.9 0.1 3.1 3 1 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 PXF44182.1 - 4.1e-08 32.8 14.7 0.72 10.3 0.0 8.5 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 PXF44182.1 - 7.3e-06 26.3 14.9 9.9e-05 22.7 0.3 6.9 6 2 2 8 8 8 1 HEAT repeats HEAT_EZ PF13513.6 PXF44182.1 - 0.0001 22.7 24.4 0.56 10.8 2.3 8.0 8 2 2 10 10 10 2 HEAT-like repeat HEAT PF02985.22 PXF44183.1 - 0.0093 16.1 10.3 5.6 7.5 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat Lectin_leg-like PF03388.13 PXF44184.1 - 4.9e-31 107.8 0.0 7.5e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 PXF44184.1 - 2e-08 34.5 0.3 7.8e-08 32.6 0.3 1.9 1 1 0 1 1 1 1 Bacterial lectin CENP-F_leu_zip PF10473.9 PXF44184.1 - 0.092 12.8 0.9 0.17 11.9 0.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2783 PF10932.8 PXF44184.1 - 0.11 12.1 0.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) DUF1631 PF07793.11 PXF44184.1 - 0.12 10.7 5.2 0.17 10.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Pro_isomerase PF00160.21 PXF44185.1 - 3.5e-28 98.8 0.0 4.5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABC_tran PF00005.27 PXF44186.1 - 1.5e-48 164.8 0.0 2.4e-28 99.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PXF44186.1 - 6.2e-28 98.2 25.7 2.4e-23 83.2 11.0 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region DUF87 PF01935.17 PXF44186.1 - 0.00075 19.7 6.7 0.0036 17.4 0.3 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 PXF44186.1 - 0.0014 18.7 0.5 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 PXF44186.1 - 0.0026 17.2 0.0 9.2 5.6 0.0 3.3 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 PXF44186.1 - 0.0028 17.1 0.7 0.22 10.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 PXF44186.1 - 0.0044 17.3 0.4 0.094 13.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PXF44186.1 - 0.01 15.8 0.4 5 7.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 PXF44186.1 - 0.016 15.7 0.5 0.77 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 PXF44186.1 - 0.028 13.4 0.5 0.072 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 PXF44186.1 - 0.03 14.7 0.2 0.76 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 PXF44186.1 - 0.036 13.8 2.0 0.51 10.1 0.8 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 PXF44186.1 - 0.049 13.1 0.5 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 PXF44186.1 - 0.05 13.4 3.7 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 PXF44186.1 - 0.052 13.3 2.1 0.068 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PXF44186.1 - 0.065 12.1 1.2 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 PXF44186.1 - 0.078 12.7 0.3 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain LEF-8 PF04941.12 PXF44186.1 - 0.19 9.9 0.0 6 5.0 0.0 2.1 2 0 0 2 2 2 0 Late expression factor 8 (LEF-8) Dynamin_N PF00350.23 PXF44186.1 - 0.62 10.1 2.4 2 8.5 1.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF2358 PF10184.9 PXF44188.1 - 9.6e-05 22.6 0.0 0.00027 21.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 PXF44188.1 - 0.00014 22.4 0.3 0.0014 19.2 0.1 2.3 2 0 0 2 2 2 1 SnoaL-like domain SOUL PF04832.12 PXF44188.1 - 0.00077 19.7 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 SOUL heme-binding protein ADK PF00406.22 PXF44190.1 - 1.7e-45 154.8 0.0 2.7e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase NDK PF00334.19 PXF44190.1 - 4.2e-43 146.6 0.0 7.8e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AAA_17 PF13207.6 PXF44190.1 - 5.6e-34 117.5 0.0 1.1e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dpy-30 PF05186.13 PXF44190.1 - 2.6e-14 52.6 0.0 3.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif AAA_18 PF13238.6 PXF44190.1 - 9.5e-10 39.1 0.0 1.6e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PXF44190.1 - 4.7e-05 23.2 0.2 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 PXF44190.1 - 0.0017 18.5 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain DDE_Tnp_IS66_C PF13817.6 PXF44190.1 - 0.039 14.2 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 IS66 C-terminal element MFAP1 PF06991.11 PXF44191.1 - 3.1e-32 112.2 16.6 3.1e-32 112.2 16.6 2.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing IMUP PF15761.5 PXF44191.1 - 1.5 9.5 14.6 0.047 14.4 5.7 2.3 1 1 1 2 2 2 0 Immortalisation up-regulated protein ClpS PF02617.17 PXF44192.1 - 1.4e-09 37.6 0.2 2.2e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SWI2_SNF2 PF18766.1 PXF44192.1 - 0.013 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Ig_mannosidase PF17753.1 PXF44193.1 - 9.5e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 PXF44193.1 - 0.00088 19.9 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 PXF44193.1 - 0.0074 16.9 0.0 0.024 15.2 0.0 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain DUF2358 PF10184.9 PXF44194.1 - 8e-18 64.8 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Biotin_lipoyl PF00364.22 PXF44194.1 - 6.3e-09 35.5 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 PXF44194.1 - 0.035 14.1 0.1 0.14 12.1 0.1 1.9 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 PXF44194.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like TIC20 PF16166.5 PXF44195.1 - 1.8e-19 70.2 6.7 2.2e-19 69.9 6.7 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Dus PF01207.17 PXF44196.1 - 1.5e-62 211.5 0.0 1.9e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PXF44196.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein SANTA PF09133.10 PXF44197.1 - 3.8e-11 43.3 0.0 8.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 PXF44197.1 - 0.14 12.4 1.0 0.41 10.9 1.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain DNA_pol_B_N PF18094.1 PXF44197.1 - 0.84 10.2 4.0 0.94 10.1 0.9 2.7 2 0 0 2 2 2 0 DNA polymerase beta N-terminal domain Presenilin PF01080.17 PXF44198.1 - 2.6e-109 365.6 0.9 5.7e-109 364.5 0.9 1.5 1 1 0 1 1 1 1 Presenilin SID-1_RNA_chan PF13965.6 PXF44198.1 - 5.7e-05 21.7 0.0 9.4e-05 21.0 0.0 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 VIT1 PF01988.19 PXF44198.1 - 0.00036 20.5 0.4 0.00036 20.5 0.4 2.4 2 0 0 2 2 2 1 VIT family DUF4834 PF16118.5 PXF44198.1 - 0.0015 19.5 0.1 0.0015 19.5 0.1 3.8 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 PXF44198.1 - 0.0061 15.6 32.3 0.0089 15.0 32.3 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Macoilin PF09726.9 PXF44198.1 - 0.041 12.5 5.6 0.058 12.0 5.6 1.1 1 0 0 1 1 1 0 Macoilin family Bac_luciferase PF00296.20 PXF44198.1 - 0.19 11.1 3.1 0.29 10.5 3.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase PA26 PF04636.13 PXF44198.1 - 0.19 10.6 10.7 0.26 10.2 10.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAPS PF04499.15 PXF44198.1 - 0.23 10.2 8.6 0.36 9.6 8.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_23 PF13476.6 PXF44198.1 - 0.66 10.4 13.3 1.3 9.5 13.3 1.4 1 0 0 1 1 1 0 AAA domain XRN_M PF17846.1 PXF44198.1 - 1.1 8.1 8.4 1.6 7.6 8.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Peptidase_S30 PF01577.16 PXF44198.1 - 3 7.4 13.3 4.5 6.8 13.3 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease DUF2052 PF09747.9 PXF44198.1 - 3.1 7.9 20.8 4.5 7.3 20.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2208 PF09973.9 PXF44198.1 - 3.7 7.1 9.3 9.2 5.8 0.8 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF5373 PF17343.2 PXF44198.1 - 5.1 6.9 15.5 2.9 7.7 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5373) CCSAP PF15748.5 PXF44198.1 - 6 7.0 29.9 9.2 6.4 29.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Dicty_REP PF05086.12 PXF44198.1 - 6 4.7 7.1 8.6 4.2 7.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.9 PXF44198.1 - 7 4.8 31.3 9.4 4.4 31.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_U57 PF05582.12 PXF44198.1 - 8.5 5.5 7.9 13 5.0 7.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Glyco_hydro_16 PF00722.21 PXF44199.1 - 1.7e-07 30.9 0.6 0.00032 20.2 0.2 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 16 WD40 PF00400.32 PXF44200.1 - 8.9e-18 64.3 6.6 8.4e-05 23.3 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-C3HC4 PF00097.25 PXF44200.1 - 0.0006 19.6 2.3 0.0013 18.6 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF44200.1 - 0.0023 17.9 3.9 0.0053 16.8 3.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF44200.1 - 0.003 17.4 1.0 0.0065 16.3 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF44200.1 - 0.0031 17.3 1.9 0.0072 16.1 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40_like PF17005.5 PXF44200.1 - 0.0032 16.8 0.0 0.0079 15.6 0.0 1.6 1 1 0 1 1 1 1 WD40-like domain zf-RING_5 PF14634.6 PXF44200.1 - 0.011 15.7 0.9 0.038 14.0 0.9 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Lzipper-MIP1 PF14389.6 PXF44200.1 - 0.2 12.0 5.8 0.48 10.7 5.8 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 zf-RING_2 PF13639.6 PXF44200.1 - 0.27 11.6 3.2 0.42 11.0 1.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 PXF44200.1 - 0.48 10.6 5.7 0.29 11.3 3.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_MalT PF17874.1 PXF44200.1 - 0.51 9.7 5.1 0.92 8.8 5.1 1.3 1 0 0 1 1 1 0 MalT-like TPR region TPT PF03151.16 PXF44201.1 - 9.3e-101 337.0 26.3 1.1e-100 336.8 26.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF44201.1 - 1.6e-09 38.1 31.2 3.9e-07 30.3 10.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PXF44201.1 - 3.2e-06 26.6 19.0 6.5e-06 25.6 19.0 1.5 1 1 0 1 1 1 1 UAA transporter family MMADHC PF10229.9 PXF44202.1 - 3.1e-18 66.5 0.0 3.7e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Pyrophosphatase PF00719.19 PXF44203.1 - 5.7e-54 182.2 0.0 9.6e-54 181.5 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase FBPase PF00316.20 PXF44203.1 - 1.1e-26 93.4 0.0 3.1e-25 88.7 0.0 2.2 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain YfmQ PF10787.9 PXF44203.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Aegerolysin PF06355.13 PXF44203.1 - 0.24 11.5 0.5 0.47 10.5 0.1 1.6 2 0 0 2 2 2 0 Aegerolysin Tetraspanin PF00335.20 PXF44205.1 - 0.00029 20.6 6.3 0.00029 20.6 6.3 2.4 2 0 0 2 2 2 1 Tetraspanin family GRA6 PF05084.13 PXF44205.1 - 0.24 11.3 0.5 0.58 10.1 0.5 1.6 1 0 0 1 1 1 0 Granule antigen protein (GRA6) PEPcase PF00311.17 PXF44206.1 - 7.3e-266 884.3 0.0 8.8e-266 884.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 PXF44206.1 - 6.3e-07 28.3 0.0 6.5e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase BSD PF03909.17 PXF44206.1 - 0.13 12.3 0.2 2.3 8.3 0.0 2.9 2 0 0 2 2 2 0 BSD domain HpcH_HpaI PF03328.14 PXF44206.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family FAD_binding_8 PF08022.12 PXF44207.1 - 1.4e-17 63.7 0.0 2.9e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 PXF44207.1 - 8.8e-15 54.9 9.8 2e-14 53.8 9.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PXF44207.1 - 3e-12 46.9 0.0 1.8e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 PXF44207.1 - 0.00086 19.9 0.0 0.043 14.5 0.0 2.4 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4179 PF13786.6 PXF44207.1 - 0.022 15.2 1.2 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4405 PF14358.6 PXF44207.1 - 4.6 7.9 16.5 16 6.1 8.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF4307 PF14155.6 PXF44208.1 - 0.089 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) SOG2 PF10428.9 PXF44208.1 - 0.85 8.7 17.8 1 8.5 17.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 PXF44208.1 - 2.7 6.6 7.6 3.2 6.3 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHQS PF01959.16 PXF44209.1 - 1e-95 320.6 0.4 1.3e-95 320.4 0.4 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase II DUF3007 PF11460.8 PXF44210.1 - 4.3e-26 91.0 0.2 6.6e-26 90.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) EAP30 PF04157.16 PXF44211.1 - 1.5e-65 220.8 0.1 1.7e-65 220.7 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family SHS2_FTSA PF02491.20 PXF44211.1 - 0.1 13.0 0.2 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA NAM-associated PF14303.6 PXF44212.1 - 9.4e-05 23.2 0.5 0.00017 22.4 0.5 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Lipocalin_8 PF16585.5 PXF44212.1 - 0.042 14.3 0.1 0.062 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipocalin-like domain DUF2845 PF11006.8 PXF44212.1 - 0.12 12.5 1.0 0.62 10.2 1.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2845) Cullin PF00888.22 PXF44219.1 - 6.6e-10 38.2 0.1 1.1e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Cullin family bZIP_1 PF00170.21 PXF44220.1 - 7.6e-08 32.3 5.7 1.6e-07 31.3 5.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PXF44220.1 - 0.00032 21.2 3.8 0.00032 21.2 3.8 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PXF44220.1 - 0.00035 20.6 7.0 0.00035 20.6 7.0 1.7 2 0 0 2 2 2 1 Basic region leucine zipper TFIIA PF03153.13 PXF44220.1 - 0.75 9.7 11.2 1.1 9.2 11.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec2p PF06428.11 PXF44220.1 - 1.6 8.8 7.0 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SUIM_assoc PF16619.5 PXF44220.1 - 5 7.3 11.5 0.17 12.0 4.8 2.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HIG_1_N PF04588.13 PXF44221.1 - 3.5e-15 56.0 2.7 4.4e-15 55.6 2.7 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Nucleotid_trans PF03407.16 PXF44222.1 - 5.6e-26 91.8 0.0 8.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1772 PF08592.11 PXF44222.1 - 0.51 10.6 3.8 1 9.7 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Branch PF02485.21 PXF44223.1 - 6.2e-26 91.4 0.0 9.3e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2826 PF11442.8 PXF44223.1 - 0.057 13.3 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) Fascin PF06268.13 PXF44223.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Fascin domain Methyltransf_21 PF05050.12 PXF44226.1 - 7.9e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Trypsin_2 PF13365.6 PXF44227.1 - 0.0059 17.5 0.1 0.047 14.6 0.1 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF44227.1 - 0.018 14.8 0.9 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Trypsin WD40 PF00400.32 PXF44228.1 - 8e-16 58.1 1.3 2e-08 34.7 0.1 4.1 3 1 0 3 3 3 3 WD domain, G-beta repeat NB-ARC PF00931.22 PXF44228.1 - 1.4e-10 40.8 0.1 2.7e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 PXF44228.1 - 0.0012 19.1 0.0 0.0045 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ANAPC4_WD40 PF12894.7 PXF44228.1 - 0.0065 16.7 0.0 0.053 13.8 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 PXF44228.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Kunitz_BPTI PF00014.23 PXF44230.1 - 1.7e-05 24.9 1.6 2.2e-05 24.6 1.6 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain REV1_C PF16727.5 PXF44231.1 - 0.037 14.4 0.8 0.8 10.1 0.2 2.6 2 1 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Sod_Cu PF00080.20 PXF44234.1 - 1.1e-31 109.9 0.1 1.5e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2706 PF10913.8 PXF44234.1 - 0.017 14.9 1.3 0.031 14.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Lactamase_B_6 PF16661.5 PXF44235.1 - 1.4e-54 184.5 0.0 2.4e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PXF44235.1 - 1.3e-17 64.1 0.0 3.3e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.6 PXF44235.1 - 6.8e-17 62.2 13.3 1.1e-15 58.2 1.0 3.4 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 PXF44235.1 - 2.9e-08 33.5 0.0 7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 PXF44235.1 - 0.0076 16.3 0.7 0.016 15.2 0.7 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF44235.1 - 0.13 11.7 0.8 0.38 10.2 0.8 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MRC1 PF09444.10 PXF44235.1 - 0.29 11.6 14.5 0.76 10.3 14.5 1.6 1 0 0 1 1 1 0 MRC1-like domain Selenoprotein_S PF06936.11 PXF44235.1 - 0.6 9.9 11.0 1.1 9.1 11.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) NPR3 PF03666.13 PXF44235.1 - 2.2 7.0 6.5 3.4 6.4 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 PXF44235.1 - 5.2 6.4 12.5 9 5.6 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF563 PF04577.14 PXF44236.1 - 7.6e-19 68.7 0.0 2.5e-18 67.0 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF563) RcpB PF16971.5 PXF44238.1 - 0.07 13.0 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit O-FucT PF10250.9 PXF44239.1 - 7.6e-07 29.1 0.0 1.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Nucleocap_ssRNA PF11128.8 PXF44239.1 - 0.041 13.6 0.0 5.3 6.7 0.0 2.2 1 1 1 2 2 2 0 Plant viral coat protein nucleocapsid O-FucT PF10250.9 PXF44240.1 - 1.5e-08 34.8 0.0 3.3e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Orbi_VP6 PF01516.16 PXF44243.1 - 0.18 11.3 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Pirin PF02678.16 PXF44244.1 - 2.8e-26 91.6 0.2 4.8e-26 90.9 0.2 1.4 1 0 0 1 1 1 1 Pirin PhoD PF09423.10 PXF44244.1 - 1.3e-17 63.9 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD PF09423.10 PXF44245.1 - 9.7e-24 84.0 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 PXF44245.1 - 8e-09 35.9 0.2 2.3e-08 34.5 0.2 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 PXF44245.1 - 9e-06 26.2 0.1 1.7e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain WD40 PF00400.32 PXF44247.1 - 7.1e-33 112.1 17.7 1.2e-05 26.0 0.0 10.1 9 0 0 9 9 9 6 WD domain, G-beta repeat NB-ARC PF00931.22 PXF44247.1 - 2e-15 56.7 0.1 3.7e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF44247.1 - 6.6e-10 39.2 6.3 0.0083 16.4 0.1 7.0 2 2 6 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF44247.1 - 1.3e-09 37.5 1.0 0.08 11.9 0.0 5.3 2 2 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 PXF44247.1 - 0.00045 20.5 0.1 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain APAF1_C PF17908.1 PXF44247.1 - 0.00074 19.5 0.1 0.0034 17.4 0.0 2.1 2 0 0 2 2 2 1 APAF-1 helical domain Nup160 PF11715.8 PXF44247.1 - 0.042 12.5 2.2 0.14 10.7 0.1 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 AAA_16 PF13191.6 PXF44247.1 - 0.11 12.9 2.4 0.13 12.6 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain Nicastrin PF05450.15 PXF44247.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Nicastrin DUF2723 PF11028.8 PXF44248.1 - 0.023 14.6 1.2 0.038 13.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF4064 PF13273.6 PXF44248.1 - 9.6 6.5 8.4 16 5.8 5.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Methyltransf_21 PF05050.12 PXF44249.1 - 1.8e-09 37.8 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PXF44249.1 - 3.9e-06 26.6 0.4 7.6e-06 25.7 0.4 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF4381 PF14316.6 PXF44250.1 - 10 6.4 10.2 6.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Rib_recp_KP_reg PF05104.12 PXF44251.1 - 6.1 7.9 15.8 10 7.2 15.8 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DNA_ligase_aden PF01653.18 PXF44256.1 - 5.4e-39 134.1 0.2 7.7e-39 133.6 0.2 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain Cytochrome_cB PF11783.8 PXF44256.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c bacterial DNA_ligase_aden PF01653.18 PXF44257.1 - 5.2e-09 35.6 0.0 6.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF44257.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain PAXIP1_C PF15364.6 PXF44257.1 - 0.077 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Nup88 PF10168.9 PXF44258.1 - 0.0045 14.9 0.1 0.0053 14.6 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore component DUF1664 PF07889.12 PXF44258.1 - 0.0085 16.1 0.7 0.8 9.8 0.1 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1664) IFT57 PF10498.9 PXF44258.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TelA PF05816.11 PXF44258.1 - 0.11 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) EzrA PF06160.12 PXF44258.1 - 0.17 10.0 0.1 0.28 9.3 0.1 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Met_gamma_lyase PF06838.11 PXF44261.1 - 5.8e-24 84.4 0.1 6.3e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase PXA PF02194.15 PXF44262.1 - 0.0097 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 PXA domain CsgG PF03783.14 PXF44262.1 - 0.018 14.3 0.3 0.1 11.9 0.1 2.1 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG Snapin_Pallidin PF14712.6 PXF44263.1 - 0.0029 18.0 0.5 0.0046 17.4 0.5 1.3 1 0 0 1 1 1 1 Snapin/Pallidin HOOK PF05622.12 PXF44263.1 - 0.0066 14.7 0.1 0.0066 14.7 0.1 1.0 1 0 0 1 1 1 1 HOOK protein N6_N4_Mtase PF01555.18 PXF44265.1 - 2.6e-10 40.4 0.0 3.1e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 DNA methylase Met_10 PF02475.16 PXF44265.1 - 0.00032 20.5 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF771 PF05595.11 PXF44269.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF771) PIF1 PF05970.14 PXF44270.1 - 6.5e-15 55.2 0.0 2.9e-08 33.3 0.0 2.9 2 1 0 2 2 2 2 PIF1-like helicase Myb_DNA-binding PF00249.31 PXF44271.1 - 0.0068 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rab_bind PF16704.5 PXF44274.1 - 0.099 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Rab binding domain PEPCK_ATP PF01293.20 PXF44275.1 - 0.17 10.5 0.1 0.62 8.7 0.0 1.8 2 1 0 2 2 2 0 Phosphoenolpyruvate carboxykinase DEAD PF00270.29 PXF44276.1 - 0.082 12.7 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Peptidase_C48 PF02902.19 PXF44279.1 - 0.00014 21.8 0.8 0.00027 20.9 0.5 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain T3SS_ATPase_C PF18269.1 PXF44280.1 - 0.077 12.9 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain Sacchrp_dh_NADP PF03435.18 PXF44283.1 - 0.023 14.9 0.1 0.026 14.8 0.1 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TIMELESS PF04821.14 PXF44286.1 - 4.6e-05 22.8 0.3 6.2e-05 22.4 0.3 1.1 1 0 0 1 1 1 1 Timeless protein ATP_bind_1 PF03029.17 PXF44286.1 - 0.023 14.5 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PPTA PF01239.22 PXF44287.1 - 8.4e-06 25.3 0.8 0.85 9.4 0.0 3.7 3 1 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat OrsD PF12013.8 PXF44291.1 - 0.0052 17.2 5.2 2.6 8.5 5.2 2.6 1 1 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D KH_5 PF13184.6 PXF44291.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 NusA-like KH domain DEAD PF00270.29 PXF44292.1 - 3.8e-13 49.6 0.0 8.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF44292.1 - 6.5e-06 26.3 0.0 3.3e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF44292.1 - 0.021 15.1 1.0 0.23 11.7 0.1 3.0 3 1 0 3 3 3 0 AAA domain SNAP PF14938.6 PXF44293.1 - 9.1e-24 84.3 0.2 7.8e-06 25.5 0.0 4.2 2 1 2 4 4 4 4 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 PXF44293.1 - 2.7e-23 80.8 22.6 0.05 13.4 0.1 12.8 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_10 PF13374.6 PXF44293.1 - 7.4e-23 79.7 19.4 0.0036 17.1 0.3 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 PXF44293.1 - 5.4e-21 73.0 0.1 0.51 10.5 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 PXF44293.1 - 1.9e-18 66.5 0.2 0.8 10.0 0.1 8.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF44293.1 - 1.2e-16 59.4 10.9 0.48 10.7 0.0 11.0 13 0 0 13 13 12 4 Tetratricopeptide repeat Sel1 PF08238.12 PXF44293.1 - 8.4e-16 58.1 0.1 0.3 11.8 0.0 8.2 9 0 0 9 9 8 3 Sel1 repeat TPR_8 PF13181.6 PXF44293.1 - 2.1e-15 55.6 16.7 0.32 11.3 0.1 10.3 12 0 0 12 12 9 3 Tetratricopeptide repeat MIT PF04212.18 PXF44293.1 - 6.8e-12 45.3 3.4 1.3 9.1 0.0 7.8 9 0 0 9 9 9 3 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 PXF44293.1 - 1.6e-09 37.3 25.7 0.48 10.2 0.1 9.7 11 1 0 11 11 9 4 TPR repeat TPR_14 PF13428.6 PXF44293.1 - 1.7e-08 34.6 0.3 29 5.8 0.0 7.8 5 2 3 8 8 8 0 Tetratricopeptide repeat 14-3-3 PF00244.20 PXF44293.1 - 3.8e-07 29.8 0.0 0.63 9.5 0.0 5.2 3 1 1 5 5 5 1 14-3-3 protein RPN7 PF10602.9 PXF44293.1 - 1.7e-06 27.8 0.9 4.8 6.9 0.0 5.4 7 1 0 7 7 4 1 26S proteasome subunit RPN7 MiaE_2 PF13794.6 PXF44293.1 - 3.8e-05 23.5 0.0 6.5 6.4 0.0 5.0 1 1 4 5 5 5 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like MIB_HERC2 PF06701.13 PXF44293.1 - 5.1e-05 23.4 3.7 6.8 7.0 0.0 6.4 3 2 4 7 7 7 0 Mib_herc2 TPR_17 PF13431.6 PXF44293.1 - 0.0001 22.4 6.6 18 6.0 0.0 7.7 7 2 0 7 7 7 0 Tetratricopeptide repeat KORA PF16509.5 PXF44293.1 - 0.0017 18.6 5.6 41 4.6 0.0 6.3 5 1 2 7 7 7 0 TrfB plasmid transcriptional repressor Colicin PF01024.19 PXF44293.1 - 0.0056 16.6 1.9 22 4.9 0.0 4.8 2 1 2 5 5 5 0 Colicin pore forming domain Nup96 PF12110.8 PXF44293.1 - 0.0091 15.1 0.0 7.2 5.6 0.0 4.0 3 1 1 4 4 4 0 Nuclear protein 96 NSF PF02071.20 PXF44293.1 - 0.022 15.3 28.6 5.5 8.2 0.2 7.8 9 0 0 9 9 6 0 Aromatic-di-Alanine (AdAR) repeat RPN6_C_helix PF18503.1 PXF44293.1 - 0.029 14.1 0.9 1.4e+02 2.3 0.0 4.5 5 0 0 5 5 5 0 26S proteasome subunit RPN6 C-terminal helix domain CBM_25 PF03423.13 PXF44293.1 - 0.032 14.5 3.9 27 5.1 0.0 4.3 3 2 2 5 5 4 0 Carbohydrate binding domain (family 25) DUF1397 PF07165.11 PXF44293.1 - 0.051 13.0 1.3 11 5.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1397) Alba PF01918.21 PXF44293.1 - 0.065 13.1 0.4 2.5e+02 1.6 0.0 4.6 5 0 0 5 5 4 0 Alba SapA PF02199.15 PXF44293.1 - 0.084 13.2 20.0 22 5.4 0.3 7.0 8 0 0 8 8 7 0 Saposin A-type domain DEAD_assoc PF08494.11 PXF44293.1 - 0.19 11.5 0.0 5.7 6.7 0.0 3.1 3 1 0 4 4 4 0 DEAD/H associated Arfaptin PF06456.13 PXF44293.1 - 0.21 11.1 0.0 12 5.3 0.0 3.1 2 1 0 3 3 3 0 Arfaptin-like domain RNA_pol_L PF01193.24 PXF44293.1 - 0.33 10.4 0.9 22 4.6 0.0 3.7 5 0 0 5 5 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain NADH_dh_m_C1 PF15088.6 PXF44293.1 - 1.3 8.7 4.5 42 3.9 0.0 4.2 5 0 0 5 5 5 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Sda PF08970.10 PXF44293.1 - 5.2 6.9 16.1 22 4.9 0.0 6.0 7 0 0 7 7 7 0 Sporulation inhibitor A TPR_1 PF00515.28 PXF44294.1 - 1.6e-07 30.8 0.2 0.066 13.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF44294.1 - 1.3e-06 28.6 0.4 0.11 12.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF44294.1 - 1.3e-06 28.0 0.1 0.97 9.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF44294.1 - 0.00011 22.2 0.6 0.72 10.2 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF44294.1 - 0.00012 21.9 1.5 0.87 9.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 PXF44294.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 PXF44294.1 - 0.0025 17.6 0.1 0.48 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF44294.1 - 0.0087 16.3 0.2 3.5 7.9 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 PXF44294.1 - 0.017 15.8 0.0 0.66 10.8 0.0 3.1 3 0 0 3 3 3 0 Sel1 repeat CHAT PF12770.7 PXF44295.1 - 7.2e-23 81.4 0.0 7.9e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 CHAT domain NinB PF05772.12 PXF44296.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 NinB protein UL11 PF11094.8 PXF44296.1 - 0.74 9.7 2.8 1.4 8.8 0.6 2.3 2 0 0 2 2 2 0 Membrane-associated tegument protein Activator-TraM PF11657.8 PXF44297.1 - 0.43 10.4 2.1 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM DUF2828 PF11443.8 PXF44298.1 - 1.4 6.9 9.5 2 6.4 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Use1 PF09753.9 PXF44298.1 - 5.1 6.8 18.9 1 9.1 14.3 2.0 2 1 1 3 3 3 0 Membrane fusion protein Use1 RR_TM4-6 PF06459.12 PXF44298.1 - 5.7 6.7 10.5 11 5.8 10.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPR_2 PF13041.6 PXF44299.1 - 2.4e-11 43.6 0.0 6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 PXF44299.1 - 1.3e-09 38.0 0.0 5.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF44299.1 - 4.2e-08 32.8 1.1 0.00073 19.2 0.1 2.4 2 1 0 2 2 2 2 PPR repeat PPR PF01535.20 PXF44299.1 - 0.00038 20.5 0.6 1.2 9.5 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 PXF44299.1 - 0.018 14.4 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 PXF44300.1 - 9.6e-30 102.5 2.7 2.9e-12 46.6 0.1 3.1 1 1 2 3 3 3 3 PPR repeat family PPR_1 PF12854.7 PXF44300.1 - 2.1e-23 81.7 0.0 4.4e-10 39.1 0.0 3.2 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 PXF44300.1 - 3e-20 71.0 0.4 3.9e-06 26.7 0.0 3.2 3 0 0 3 3 3 3 PPR repeat PPR_3 PF13812.6 PXF44300.1 - 6.7e-18 64.5 0.1 1.1e-11 44.7 0.1 2.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF44300.1 - 2.3e-08 33.7 0.0 3.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PXF44300.1 - 3.5e-05 23.6 0.0 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial ATPase expression MRP-S27 PF10037.9 PXF44300.1 - 0.0093 14.9 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 TPR_1 PF00515.28 PXF44300.1 - 0.0094 15.7 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.20 PXF44300.1 - 0.017 15.0 0.0 0.96 9.3 0.0 2.5 2 1 0 2 2 2 0 Region in Clathrin and VPS TPR_14 PF13428.6 PXF44300.1 - 0.029 15.2 0.0 0.76 10.8 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 PXF44300.1 - 0.029 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF44300.1 - 0.031 14.5 0.3 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex19 PF04614.12 PXF44300.1 - 0.038 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Pex19 protein family TPR_19 PF14559.6 PXF44300.1 - 0.11 13.0 0.1 2.8 8.5 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 PXF44301.1 - 4.3e-08 33.2 0.0 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.7 PXF44301.1 - 0.0013 18.4 0.0 2.6 7.8 0.0 3.1 3 0 0 3 3 3 2 PPR repeat PPR PF01535.20 PXF44301.1 - 0.0038 17.4 0.6 0.24 11.7 0.0 3.7 4 1 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 PXF44301.1 - 0.0052 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF44301.1 - 0.027 13.9 0.0 0.5 9.7 0.0 1.5 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP CH PF00307.31 PXF44304.1 - 5e-09 36.3 0.0 5.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PXF44304.1 - 0.023 14.5 0.1 0.074 12.9 0.1 1.9 1 1 0 1 1 1 0 CAMSAP CH domain DUF4484 PF14831.6 PXF44307.1 - 0.14 12.2 3.5 0.16 12.0 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) FAM178 PF14816.6 PXF44307.1 - 0.2 10.6 3.3 0.23 10.4 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 NPIP PF06409.11 PXF44307.1 - 0.32 10.0 3.3 0.39 9.8 3.3 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF2229 PF09989.9 PXF44307.1 - 0.34 10.5 3.0 0.31 10.6 1.8 1.5 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) INTAP PF16617.5 PXF44308.1 - 4 7.8 11.7 8.2 6.8 11.7 1.5 1 1 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region MerR-DNA-bind PF09278.11 PXF44309.1 - 0.057 14.0 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 MerR, DNA binding DUF771 PF05595.11 PXF44310.1 - 0.058 13.4 0.6 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF771) PIF1 PF05970.14 PXF44311.1 - 1.9e-31 109.5 0.3 2.5e-31 109.2 0.3 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 PXF44311.1 - 4.5e-13 49.3 0.2 3.7e-12 46.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF44311.1 - 3.5e-10 40.4 0.1 8.3e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 PXF44311.1 - 8.8e-05 21.6 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 PXF44311.1 - 0.00053 19.0 0.2 0.00077 18.5 0.2 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF853 PF05872.12 PXF44311.1 - 0.011 14.4 0.3 0.014 14.0 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 PXF44311.1 - 0.031 14.0 0.8 6.3 6.5 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 PXF44311.1 - 0.098 12.4 0.4 0.63 9.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.14 PXF44311.1 - 0.13 12.1 0.5 0.73 9.7 0.5 2.0 1 1 1 2 2 2 0 Helicase DUF2075 PF09848.9 PXF44311.1 - 0.15 11.2 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1611 PF07755.11 PXF44311.1 - 0.18 11.1 0.4 0.27 10.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Cob_adeno_trans PF01923.18 PXF44312.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Methyltransf_21 PF05050.12 PXF44313.1 - 4.6e-08 33.3 0.0 3e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase FkbM domain VCBS PF13517.6 PXF44315.1 - 4.7e-27 94.4 34.4 1.4e-11 44.8 6.6 5.7 3 1 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF44315.1 - 1.4e-10 41.1 17.4 8.4e-05 22.6 0.0 5.7 5 0 0 5 5 5 3 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF44315.1 - 1.4e-06 28.1 1.4 2.8e-06 27.2 1.4 1.5 1 0 0 1 1 1 1 ASPIC and UnbV EMP70 PF02990.16 PXF44316.1 - 2.2e-44 152.0 1.6 2.6e-44 151.8 1.6 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 YkyA PF10368.9 PXF44317.1 - 7.7 6.1 10.2 0.1 12.3 1.1 2.2 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein VCBS PF13517.6 PXF44320.1 - 4e-30 104.2 46.4 4.9e-12 46.3 7.6 6.5 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF44320.1 - 2.3e-08 34.0 28.8 0.0027 17.8 0.2 5.8 7 0 0 7 7 7 4 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF44320.1 - 5.3e-06 26.3 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 ASPIC and UnbV VCBS PF13517.6 PXF44321.1 - 1.3e-25 89.7 34.1 2.6e-12 47.2 4.1 5.5 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 PXF44321.1 - 2.3e-07 30.7 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 PXF44321.1 - 0.0002 21.4 28.1 0.062 13.4 0.1 5.6 6 0 0 6 6 6 3 FG-GAP repeat FlaE PF07559.14 PXF44321.1 - 0.011 16.3 0.1 0.046 14.3 0.0 2.1 2 1 0 2 2 2 0 Flagellar basal body protein FlaE Itfg2 PF15907.5 PXF44321.1 - 0.054 12.5 0.1 11 5.0 0.0 2.7 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 Holin_BlyA PF05102.12 PXF44322.1 - 0.16 12.0 0.6 0.51 10.3 0.6 1.8 1 0 0 1 1 1 0 holin, BlyA family DUF4658 PF15555.6 PXF44323.1 - 0.14 12.3 0.9 4.4 7.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Ninjurin PF04923.12 PXF44323.1 - 0.46 10.4 5.3 0.14 12.1 0.4 2.5 3 0 0 3 3 3 0 Ninjurin PEP-utilizers_C PF02896.18 PXF44324.1 - 1e-90 303.9 0.1 1.5e-90 303.3 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 PXF44324.1 - 6.4e-67 226.2 0.0 1.8e-63 214.8 0.0 3.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 PXF44324.1 - 1.2e-27 95.4 1.7 2.6e-27 94.3 1.7 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain SIMPL PF04402.14 PXF44325.1 - 1.7e-46 159.2 7.2 1.9e-46 159.0 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SIMPL PF04402.14 PXF44326.1 - 1.3e-22 81.3 0.2 1.5e-22 81.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SIMPL PF04402.14 PXF44327.1 - 3.8e-46 158.1 5.1 4.2e-46 157.9 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) PilM PF07419.12 PXF44327.1 - 0.057 13.6 0.0 3.2 7.9 0.0 2.2 1 1 1 2 2 2 0 PilM SIMPL PF04402.14 PXF44328.1 - 5.6e-43 147.7 4.2 6.4e-43 147.5 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) MFS_1 PF07690.16 PXF44333.1 - 1.6e-19 70.1 22.9 1.6e-19 70.1 22.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 PXF44333.1 - 1.1e-12 47.3 4.0 1.1e-12 47.3 4.0 2.7 3 1 0 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 PXF44333.1 - 0.05 11.8 1.1 0.1 10.8 1.1 1.4 1 0 0 1 1 1 0 BT1 family DUF4293 PF14126.6 PXF44333.1 - 0.56 10.5 4.2 0.26 11.5 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) MFS_1 PF07690.16 PXF44334.1 - 1.2e-11 44.1 37.1 1.2e-11 44.1 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PXF44334.1 - 6.1e-10 38.2 5.8 6.1e-10 38.2 5.8 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 PXF44334.1 - 1.9e-09 37.1 1.9 1.9e-09 37.1 1.9 2.0 2 0 0 2 2 2 1 PUCC protein BT1 PF03092.16 PXF44334.1 - 0.001 17.4 6.0 0.0019 16.5 6.0 1.4 1 0 0 1 1 1 1 BT1 family Metallophos_2 PF12850.7 PXF44336.1 - 0.00021 21.5 0.0 0.00065 19.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNase_HII PF01351.18 PXF44337.1 - 6.7e-38 130.5 0.0 9.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Gcw_chp PF09694.10 PXF44337.1 - 0.0033 17.4 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (Gcw_chp) Headcase PF16002.5 PXF44338.1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Headcase protein Chromo PF00385.24 PXF44341.1 - 1.6e-08 34.3 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tox-MPTase5 PF15641.6 PXF44345.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 DUF393 PF04134.12 PXF44346.1 - 1.1e-22 81.4 0.1 2.1e-22 80.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF393 DUF836 PF05768.14 PXF44346.1 - 0.018 15.4 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 PXF44346.1 - 0.14 11.9 0.1 4.3 7.0 0.1 2.2 1 1 1 2 2 2 0 Redoxin DUF393 PF04134.12 PXF44347.1 - 1.4e-22 81.1 0.0 2.8e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF836 PF05768.14 PXF44347.1 - 0.022 15.2 0.0 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 PXF44347.1 - 0.19 11.4 0.1 3 7.5 0.1 2.2 1 1 1 2 2 2 0 Redoxin Asparaginase PF00710.20 PXF44349.1 - 2.4e-62 209.9 0.0 3.9e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PXF44349.1 - 2.9e-14 53.3 0.0 5.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Sel1 PF08238.12 PXF44350.1 - 2.7e-08 34.2 1.1 0.15 12.8 0.1 5.2 5 0 0 5 5 5 3 Sel1 repeat PNMA PF14893.6 PXF44350.1 - 0.03 13.7 0.2 0.043 13.2 0.2 1.2 1 0 0 1 1 1 0 PNMA YL1 PF05764.13 PXF44351.1 - 0.11 12.6 16.6 0.17 12.0 16.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 PXF44351.1 - 5.7 5.1 14.9 8 4.6 14.9 1.2 1 0 0 1 1 1 0 CDC45-like protein VirionAssem_T7 PF11653.8 PXF44352.1 - 0.052 14.1 2.2 0.11 13.1 2.2 1.5 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein phiKZ_IP PF12699.7 PXF44352.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins TPR_14 PF13428.6 PXF44354.1 - 0.2 12.6 3.1 0.31 12.0 0.9 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Phage_ABA_S PF18066.1 PXF44355.1 - 0.076 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Phage ABA sandwich domain Cation_ATPase_C PF00689.21 PXF44356.1 - 5.4e-12 45.8 0.0 9.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1126 PF06565.12 PXF44357.1 - 0.098 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 DUF1126 PH-like domain KH_6 PF15985.5 PXF44358.1 - 0.0018 18.6 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 KH domain UCMA PF17085.5 PXF44359.1 - 0.21 11.6 2.8 0.41 10.6 0.0 2.2 2 1 0 2 2 2 0 Unique cartilage matrix associated protein DUF659 PF04937.15 PXF44360.1 - 3.8e-19 69.1 0.1 6.3e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) PIRT PF15099.6 PXF44363.1 - 0.028 14.0 0.2 0.092 12.3 0.1 1.9 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family DUF1056 PF06341.11 PXF44363.1 - 0.092 13.1 0.8 0.31 11.4 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Dynamin_N PF00350.23 PXF44364.1 - 0.007 16.4 0.0 0.0094 16.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin family VCBS PF13517.6 PXF44365.1 - 1.1e-25 90.0 35.9 7.3e-11 42.5 5.7 5.3 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF44365.1 - 1.5e-10 41.0 21.8 0.0074 16.4 0.4 5.8 6 0 0 6 6 6 5 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF44365.1 - 3.5e-05 23.7 0.0 9.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV Itfg2 PF15907.5 PXF44365.1 - 0.035 13.1 1.1 5.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 GSDH PF07995.11 PXF44365.1 - 0.09 12.1 0.1 0.28 10.5 0.1 1.7 1 1 1 2 2 2 0 Glucose / Sorbosone dehydrogenase PAP2 PF01569.21 PXF44366.1 - 8.6e-09 35.3 0.1 7.5e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 PAP2 superfamily VCPO_N PF17897.1 PXF44366.1 - 6.2e-05 22.9 0.3 0.00018 21.4 0.3 1.8 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain Toxin_11 PF07473.11 PXF44366.1 - 0.21 11.7 6.4 5.4 7.2 0.5 2.4 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species EB PF01683.18 PXF44366.1 - 1.6 9.1 9.4 20 5.6 6.5 2.3 1 1 1 2 2 2 0 EB module Nodulin_late PF07127.11 PXF44366.1 - 1.7 9.0 5.8 0.23 11.8 0.4 2.1 2 0 0 2 2 2 0 Late nodulin protein DX PF01666.17 PXF44366.1 - 4.2 7.9 6.8 0.51 10.8 0.8 2.2 2 0 0 2 2 2 0 DX module PAP2 PF01569.21 PXF44371.1 - 1.2e-08 34.8 0.0 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 PAP2 superfamily VCPO_N PF17897.1 PXF44371.1 - 5.2e-05 23.1 0.4 0.00013 21.9 0.4 1.7 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain Nodulin_late PF07127.11 PXF44371.1 - 0.0099 16.2 0.2 0.0099 16.2 0.2 2.1 2 0 0 2 2 2 1 Late nodulin protein DX PF01666.17 PXF44371.1 - 0.23 12.0 7.1 0.68 10.4 1.1 2.4 2 0 0 2 2 2 0 DX module Toxin_11 PF07473.11 PXF44371.1 - 0.81 9.8 11.1 4.9 7.3 0.4 2.4 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species EB PF01683.18 PXF44371.1 - 1.8 8.9 12.5 5.8 7.3 1.8 2.4 1 1 0 2 2 2 0 EB module PAP2 PF01569.21 PXF44372.1 - 6.4e-09 35.7 0.1 6.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 PAP2 superfamily VCPO_N PF17897.1 PXF44372.1 - 0.23 11.2 0.5 0.6 9.9 0.5 1.8 1 1 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain MRP-S31 PF15433.6 PXF44374.1 - 0.01 15.5 0.1 0.01 15.5 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Sec-ASP3 PF15432.6 PXF44374.1 - 0.05 13.7 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 SR-25 PF10500.9 PXF44375.1 - 0.26 10.9 6.3 0.49 10.0 6.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COG6 PF06419.11 PXF44376.1 - 2.3e-146 488.6 1.2 2.6e-146 488.5 1.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Vps52 PF04129.12 PXF44376.1 - 0.003 16.4 1.0 0.0048 15.7 0.5 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Prominin PF05478.11 PXF44376.1 - 0.011 13.7 0.2 0.022 12.7 0.2 1.4 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.6 PXF44376.1 - 0.032 12.9 2.0 0.2 10.2 0.3 2.1 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.12 PXF44376.1 - 0.032 14.2 2.1 0.062 13.3 1.0 2.1 2 0 0 2 2 2 0 Laminin Domain II HsbA PF12296.8 PXF44376.1 - 0.049 14.1 2.2 0.1 13.0 1.3 2.1 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Noelin-1 PF12308.8 PXF44376.1 - 0.1 12.6 1.6 0.86 9.6 0.4 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein Tropomyosin PF00261.20 PXF44376.1 - 0.1 11.9 10.1 0.63 9.4 0.4 2.8 3 0 0 3 3 3 0 Tropomyosin Occludin_ELL PF07303.13 PXF44376.1 - 0.17 12.7 0.7 0.63 10.8 0.1 2.3 2 1 0 2 2 2 0 Occludin homology domain EccE PF11203.8 PXF44376.1 - 0.91 9.9 7.1 1.4 9.3 3.1 3.2 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE MscS_porin PF12795.7 PXF44376.1 - 3.9 7.0 15.4 0.27 10.7 9.8 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain WD40 PF00400.32 PXF44377.1 - 5.7e-44 147.2 24.3 1.3e-07 32.2 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 PXF44377.1 - 2.6e-37 128.0 0.3 3.9e-37 127.4 0.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 PXF44377.1 - 8.8e-14 51.6 0.1 0.0047 17.2 0.0 5.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain AAR2 PF05282.11 PXF44377.1 - 0.046 13.1 0.4 0.12 11.8 0.4 1.6 1 0 0 1 1 1 0 AAR2 protein Nup160 PF11715.8 PXF44377.1 - 0.075 11.7 0.2 0.3 9.7 0.1 2.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 PXF44377.1 - 0.083 12.2 0.1 14 4.9 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 PXF44377.1 - 0.12 11.6 0.0 6.7 5.9 0.0 3.0 3 1 0 3 3 3 0 WD40-like domain V_ATPase_I PF01496.19 PXF44378.1 - 7e-287 953.7 0.0 7.9e-287 953.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ISK_Channel PF02060.15 PXF44378.1 - 9.3 6.0 9.4 2.9 7.7 0.1 3.3 3 0 0 3 3 3 0 Slow voltage-gated potassium channel TraF PF13728.6 PXF44379.1 - 0.0074 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.20 PXF44379.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin HEM4 PF02602.15 PXF44380.1 - 2.7e-28 98.9 0.0 3.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1887 PF09002.11 PXF44380.1 - 0.041 12.6 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) EMP70 PF02990.16 PXF44381.1 - 8e-168 559.3 0.3 9.5e-168 559.1 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4079 PF13301.6 PXF44381.1 - 1.6 8.9 4.7 16 5.7 4.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) EMP70 PF02990.16 PXF44382.1 - 8.1e-162 539.5 0.5 1.1e-161 539.0 0.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 PXF44383.1 - 9e-184 611.9 5.1 9e-184 611.9 5.1 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 NUDIX PF00293.28 PXF44384.1 - 1.7e-16 60.4 0.2 2.3e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain AhpC-TSA PF00578.21 PXF44385.1 - 2e-15 56.8 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF44385.1 - 5e-13 49.0 0.0 6.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 PXF44385.1 - 0.0001 22.7 0.0 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain GFO_IDH_MocA PF01408.22 PXF44387.1 - 8.5e-13 49.2 0.1 1.9e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF44387.1 - 0.00069 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PDH PF02153.17 PXF44387.1 - 0.021 13.9 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Pesticin PF16754.5 PXF44387.1 - 0.025 14.5 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term DUF2321 PF10083.9 PXF44387.1 - 0.072 12.7 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) TFCD_C PF12612.8 PXF44388.1 - 1.9e-15 57.2 0.0 5.7e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 PXF44388.1 - 0.0027 18.1 21.5 2 8.8 2.4 6.5 6 0 0 6 6 6 4 HEAT repeats CLTH PF10607.9 PXF44389.1 - 5.8e-35 120.4 1.1 7.7e-35 120.0 1.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PXF44389.1 - 1.1e-09 37.9 6.5 3.1e-09 36.5 0.6 3.1 4 0 0 4 4 4 2 LisH Amino_oxidase PF01593.24 PXF44390.1 - 6.1e-59 200.5 0.0 6.9e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF44390.1 - 6.4e-11 42.3 0.1 1.3e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF44390.1 - 8.4e-08 32.2 0.0 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PXF44390.1 - 0.0006 18.6 0.4 0.001 17.9 0.2 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 PXF44390.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF44390.1 - 0.0021 18.1 0.0 0.0063 16.5 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 PXF44390.1 - 0.0042 16.4 0.1 0.0094 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PXF44390.1 - 0.0064 15.6 0.1 0.0098 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 PXF44390.1 - 0.036 13.1 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 PXF44390.1 - 0.048 14.2 0.4 6.5 7.4 0.0 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PXF44390.1 - 0.2 10.9 0.1 0.4 10.0 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase SPAN PF02510.14 PXF44390.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens protein MA3 PF02847.17 PXF44391.1 - 1.5e-11 44.3 0.2 3.5e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 PXF44391.1 - 2.4e-08 33.9 0.0 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain YqzE PF14038.6 PXF44391.1 - 2.5 8.2 6.3 62 3.7 8.2 2.3 2 0 0 2 2 2 0 YqzE-like protein Acetyltransf_3 PF13302.7 PXF44392.1 - 2.8e-18 66.9 0.0 4.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF44392.1 - 4.5e-08 33.3 0.0 5.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 PXF44392.1 - 0.00057 19.6 0.1 0.0013 18.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF44392.1 - 0.0031 17.5 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein UPF0160 PF03690.13 PXF44393.1 - 8.9e-127 423.1 0.0 1e-126 422.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF4735 PF15882.5 PXF44393.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) PAPS_reduct PF01507.19 PXF44394.1 - 1.2e-23 84.0 0.2 2.8e-21 76.3 0.2 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Adeno_terminal PF02459.15 PXF44394.1 - 0.0092 14.4 0.0 0.0096 14.4 0.0 1.1 1 0 0 1 1 1 1 Adenoviral DNA terminal protein WD-3 PF09765.9 PXF44395.1 - 2.2e-70 237.2 0.0 2.6e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 PXF44395.1 - 2.3e-25 88.6 1.7 4.4e-25 87.6 1.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 PXF44395.1 - 0.0018 18.6 3.1 0.0018 18.6 3.1 2.2 2 0 0 2 2 2 1 Ring finger domain UvrA_inter PF17760.1 PXF44395.1 - 0.023 14.7 0.1 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 UvrA interaction domain PHD PF00628.29 PXF44395.1 - 0.1 12.5 3.7 0.25 11.2 3.7 1.7 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 PXF44395.1 - 0.14 12.4 1.1 0.41 10.9 1.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain SEP PF08059.13 PXF44396.1 - 2.8e-23 82.3 1.2 3.5e-23 82.0 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 PXF44396.1 - 1.3e-15 56.9 0.1 3.6e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 PXF44396.1 - 5.3e-14 52.2 0.1 9.3e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 UBX domain Rad51 PF08423.11 PXF44397.1 - 0.00011 21.5 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 Pkinase PF00069.25 PXF44398.1 - 2.6e-19 69.6 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44398.1 - 1.5e-13 50.6 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF44398.1 - 1.1e-06 28.8 3.1 0.0053 16.7 2.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PXF44398.1 - 0.0038 16.9 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PXF44398.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 PXF44399.1 - 7.5e-20 71.2 3.0 2.6e-15 56.6 1.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PXF44399.1 - 3.1e-19 67.0 6.4 3.4e-08 32.5 0.2 4.5 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PXF44399.1 - 4.2e-17 60.6 1.0 1.5e-05 24.5 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PXF44399.1 - 5e-16 58.3 7.9 7e-13 48.2 0.8 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PXF44399.1 - 1.8e-07 30.3 2.5 0.0072 15.8 0.1 3.6 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 PXF44399.1 - 2.1e-07 31.1 0.1 5.7e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PXF44399.1 - 1.1e-05 25.3 0.5 0.13 12.3 0.1 3.1 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 PXF44399.1 - 9.3e-05 22.4 0.6 1.6 8.8 0.0 3.3 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) SurA_N_3 PF13624.6 PXF44399.1 - 0.0055 16.5 0.9 0.0055 16.5 0.9 1.4 2 0 0 2 2 2 1 SurA N-terminal domain Dockerin_1 PF00404.18 PXF44399.1 - 0.011 15.9 0.3 0.025 14.7 0.3 1.8 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_14 PF17959.1 PXF44399.1 - 0.045 14.1 1.0 2.6 8.4 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 PXF44399.1 - 0.057 13.3 2.8 0.11 12.3 2.3 1.7 1 1 0 1 1 1 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 PXF44399.1 - 0.057 13.7 1.3 0.12 12.7 1.3 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Glyco_trans_1_2 PF13524.6 PXF44399.1 - 0.076 13.4 0.2 0.19 12.2 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 Ribosomal_L29 PF00831.23 PXF44399.1 - 0.11 12.5 7.3 0.63 10.1 1.8 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein MgtE_N PF03448.17 PXF44399.1 - 0.13 12.9 0.5 0.13 12.9 0.5 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain Tsc35 PF15079.6 PXF44399.1 - 1.7 8.2 9.2 0.087 12.4 2.7 2.0 2 0 0 2 2 2 0 Testis-specific protein 35 DUF296 PF03479.15 PXF44400.1 - 0.00097 19.5 0.0 0.0042 17.5 0.0 1.9 1 1 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Pentapeptide PF00805.22 PXF44401.1 - 3.3e-27 93.7 22.5 2.3e-11 43.1 2.0 3.7 2 1 2 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PXF44401.1 - 3.8e-17 62.2 2.5 2.1e-11 43.8 1.6 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PXF44401.1 - 2.4e-14 53.2 21.1 2.1e-06 27.8 5.5 3.0 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) COPIIcoated_ERV PF07970.12 PXF44402.1 - 8.5e-31 107.5 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PXF44402.1 - 5.4e-23 81.2 1.3 8.4e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 PXF44402.1 - 1.7e-22 79.3 0.3 3.2e-22 78.4 0.3 1.5 1 0 0 1 1 1 1 Thioredoxin Sucrose_synth PF00862.19 PXF44402.1 - 0.057 11.7 0.0 0.085 11.2 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase Tachystatin_A PF11406.8 PXF44404.1 - 0.0038 17.3 19.1 0.11 12.5 3.4 4.4 4 0 0 4 4 4 2 Antimicrobial peptide tachystatin A Toxin_24 PF08094.11 PXF44404.1 - 0.037 13.8 0.9 0.037 13.8 0.9 4.8 5 1 0 5 5 5 0 Conotoxin TVIIA/GS family Kazal_2 PF07648.15 PXF44404.1 - 0.06 13.5 0.8 0.06 13.5 0.8 2.8 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain NAD_binding_2 PF03446.15 PXF44408.1 - 7.4e-27 94.5 0.0 1.5e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PXF44408.1 - 6.4e-21 74.9 0.5 1e-20 74.2 0.5 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Methyltr_RsmB-F PF01189.17 PXF44411.1 - 6.2e-66 221.9 0.0 1.4e-65 220.7 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 PXF44411.1 - 9e-11 42.1 0.1 4.9e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 PXF44411.1 - 0.009 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Phage_holin_2_4 PF16082.5 PXF44411.1 - 0.19 11.5 2.8 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like FAD_binding_1 PF00667.20 PXF44412.1 - 2e-32 112.5 0.1 3.2e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PXF44412.1 - 7.7e-26 91.0 0.0 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PXF44412.1 - 9.3e-16 58.4 0.0 2.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 PXF44412.1 - 0.026 14.2 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain SIS_2 PF13580.6 PXF44412.1 - 0.084 12.9 0.5 0.36 10.8 0.2 2.1 2 0 0 2 2 2 0 SIS domain ARID PF01388.21 PXF44413.1 - 1.2e-06 29.1 0.3 0.34 11.6 0.0 5.0 2 2 3 5 5 5 1 ARID/BRIGHT DNA binding domain P22_Cro PF14549.6 PXF44413.1 - 0.0003 20.6 1.6 18 5.3 0.0 5.3 5 1 0 5 5 5 2 DNA-binding transcriptional regulator Cro YdaS_antitoxin PF15943.5 PXF44413.1 - 0.051 13.5 0.0 75 3.3 0.1 4.4 5 0 0 5 5 5 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Bud13 PF09736.9 PXF44414.1 - 2e-14 54.2 0.3 2e-14 54.2 0.3 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Pkinase PF00069.25 PXF44415.1 - 3.4e-67 226.6 0.0 4.6e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44415.1 - 3.8e-35 121.4 0.0 5.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF44415.1 - 0.00051 19.5 0.3 0.0009 18.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF44415.1 - 0.0011 18.0 0.1 0.0024 16.9 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PXF44415.1 - 0.0044 17.0 0.4 0.19 11.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF44415.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.10 PXF44416.1 - 0.0021 17.4 3.4 0.0021 17.4 3.4 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PXF44416.1 - 0.042 14.7 0.0 0.11 13.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 PXF44416.1 - 0.05 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 CD34_antigen PF06365.12 PXF44416.1 - 0.059 12.9 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family Syndecan PF01034.20 PXF44416.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Mitofilin PF09731.9 PXF44416.1 - 0.34 9.7 1.7 0.39 9.5 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TMEM154 PF15102.6 PXF44416.1 - 0.71 9.8 6.7 13 5.6 6.7 2.5 1 1 0 1 1 1 0 TMEM154 protein family SPC25 PF06703.11 PXF44418.1 - 9.9e-26 90.5 0.1 1.5e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Na_H_antiport_3 PF07399.11 PXF44418.1 - 0.0027 16.7 0.4 0.0035 16.3 0.4 1.1 1 0 0 1 1 1 1 Putative Na+/H+ antiporter DUF2705 PF10920.8 PXF44418.1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) DUF2207 PF09972.9 PXF44418.1 - 0.055 12.2 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FeS_assembly_P PF01883.19 PXF44419.1 - 1e-08 35.2 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Amino_oxidase PF01593.24 PXF44420.1 - 8.8e-18 64.8 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF44420.1 - 1.2e-11 44.6 0.5 4e-11 43.0 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF44420.1 - 4.8e-08 33.0 0.0 5.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF44420.1 - 1.4e-06 27.8 3.0 3e-05 23.4 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF44420.1 - 6.9e-06 25.4 2.7 0.0023 17.1 1.4 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 PXF44420.1 - 0.0001 21.2 0.9 0.002 16.9 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 PXF44420.1 - 0.00046 20.7 1.5 0.052 14.1 0.3 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF44420.1 - 0.00055 19.3 1.2 0.0041 16.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 PXF44420.1 - 0.0011 18.2 0.4 0.0017 17.5 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 PXF44420.1 - 0.0013 18.7 0.1 0.0031 17.5 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 PXF44420.1 - 0.002 17.5 0.9 0.004 16.5 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 PXF44420.1 - 0.0026 17.2 0.7 0.032 13.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF1188 PF06690.11 PXF44420.1 - 0.0046 16.5 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.18 PXF44420.1 - 0.019 14.9 0.4 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 PXF44420.1 - 0.024 13.9 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 PXF44420.1 - 0.035 13.2 2.8 0.039 13.0 1.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 PXF44420.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCRA PF06100.11 PXF44420.1 - 0.065 12.0 0.1 0.88 8.3 0.0 2.1 2 0 0 2 2 2 0 MCRA family Pyr_redox_3 PF13738.6 PXF44420.1 - 0.084 12.1 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PXF44420.1 - 0.085 12.5 0.7 0.3 10.7 0.6 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA CvfB_WH PF17783.1 PXF44420.1 - 0.17 11.7 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 CvfB-like winged helix domain Trp_halogenase PF04820.14 PXF44420.1 - 0.45 9.3 3.1 1.4 7.7 1.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase CCDC-167 PF15188.6 PXF44421.1 - 0.0056 17.0 0.1 0.0086 16.4 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 5-FTHF_cyc-lig PF01812.20 PXF44422.1 - 3.3e-40 137.9 0.0 3.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family HLH PF00010.26 PXF44424.1 - 5.2e-05 23.1 0.5 9.4e-05 22.3 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bHLH-MYC_N PF14215.6 PXF44424.1 - 0.055 13.7 1.3 0.76 10.0 0.0 2.4 2 1 0 3 3 3 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal SfLAP PF11139.8 PXF44425.1 - 0.0014 18.1 3.0 0.0014 18.1 3.0 2.7 2 1 0 3 3 3 1 Sap, sulfolipid-1-addressing protein DUF4131 PF13567.6 PXF44425.1 - 0.0038 16.9 0.1 0.0038 16.9 0.1 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 PXF44425.1 - 0.096 12.7 7.9 0.24 11.4 1.5 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Claudin_2 PF13903.6 PXF44425.1 - 5.2 6.8 14.4 0.33 10.7 6.4 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Myb_DNA-binding PF00249.31 PXF44426.1 - 2.4e-06 27.6 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1086 PF06461.11 PXF44426.1 - 0.18 11.7 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) ANAPC4 PF12896.7 PXF44427.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 PXF44427.1 - 3.3e-12 46.5 0.1 3e-11 43.5 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Talin_middle PF09141.10 PXF44427.1 - 0.045 13.8 0.2 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Talin, middle domain Ribosomal_L34 PF00468.17 PXF44427.1 - 0.12 12.4 0.8 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L34 Cys_box PF17869.1 PXF44427.1 - 0.49 10.6 3.7 0.29 11.3 0.2 2.4 3 0 0 3 3 3 0 Anosmin cysteine rich domain DUF659 PF04937.15 PXF44429.1 - 6.1e-14 52.1 0.0 7.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GDP_Man_Dehyd PF16363.5 PXF44430.1 - 4.5e-09 36.2 0.0 4.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF44430.1 - 6.4e-05 22.5 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family STAG PF08514.11 PXF44433.1 - 3.2e-20 72.2 0.7 1.6e-18 66.7 0.1 2.6 2 1 0 2 2 2 1 STAG domain HCR PF07111.12 PXF44433.1 - 0.00095 17.4 2.6 0.0014 16.8 2.6 1.1 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) HEAT PF02985.22 PXF44433.1 - 0.0033 17.6 0.2 0.86 10.0 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat FAM76 PF16046.5 PXF44433.1 - 0.007 15.8 0.8 0.01 15.2 0.8 1.2 1 0 0 1 1 1 1 FAM76 protein DUF4042 PF13251.6 PXF44433.1 - 0.0074 16.0 0.1 0.058 13.1 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4042) Cnd1 PF12717.7 PXF44433.1 - 0.022 14.8 0.2 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Spc7 PF08317.11 PXF44433.1 - 0.26 10.2 3.1 0.4 9.5 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Transposase_21 PF02992.14 PXF44436.1 - 1.1e-14 54.2 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 PXF44436.1 - 6.1e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) EF-hand_1 PF00036.32 PXF44438.1 - 8.9e-16 56.2 0.0 3.3e-07 29.4 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PXF44438.1 - 7.9e-13 48.7 0.2 8.9e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PXF44438.1 - 1.4e-12 46.4 0.4 0.00089 19.0 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PXF44438.1 - 4.7e-07 29.5 0.9 0.0022 17.8 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain pair Glyoxalase PF00903.25 PXF44438.1 - 1.4e-06 28.5 0.0 6.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_5 PF13202.6 PXF44438.1 - 0.00019 20.8 0.8 0.22 11.1 0.0 3.0 3 0 0 3 3 3 2 EF hand Glyoxalase_4 PF13669.6 PXF44438.1 - 0.023 14.9 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_4 PF12763.7 PXF44438.1 - 0.044 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PXF44438.1 - 0.12 12.7 0.0 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain RNase_H_2 PF13482.6 PXF44439.1 - 0.0071 16.3 0.0 0.0083 16.1 0.0 1.1 1 0 0 1 1 1 1 RNase_H superfamily HTH_11 PF08279.12 PXF44439.1 - 0.0095 15.9 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 HTH domain tRNA-synt_1 PF00133.22 PXF44440.1 - 5.1e-20 71.3 0.0 6.1e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF44440.1 - 2.2e-07 30.0 0.0 2.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PXF44440.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF44440.1 - 0.0024 16.8 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 PXF44441.1 - 4.4e-81 272.9 1.3 5.9e-81 272.5 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 PXF44441.1 - 1.1e-10 41.3 0.0 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DpnD-PcfM PF14207.6 PXF44441.1 - 0.019 14.9 0.8 0.047 13.6 0.5 1.9 2 0 0 2 2 2 0 DpnD/PcfM-like protein VESA1_N PF12785.7 PXF44442.1 - 1 8.3 10.7 1 8.3 10.7 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 TCR PF03638.15 PXF44442.1 - 1.4 9.3 21.0 2.2 8.6 21.0 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain RVT_2 PF07727.14 PXF44445.1 - 8.3e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF496 PF04363.12 PXF44447.1 - 0.082 12.9 0.1 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) STAG PF08514.11 PXF44448.1 - 2.7e-20 72.4 1.0 4.6e-20 71.6 0.6 1.6 1 1 0 1 1 1 1 STAG domain HCR PF07111.12 PXF44448.1 - 0.0094 14.1 1.4 0.013 13.7 1.4 1.1 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) FAM76 PF16046.5 PXF44448.1 - 0.015 14.6 0.5 0.018 14.4 0.5 1.1 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 PXF44449.1 - 0.00088 19.2 5.0 0.00088 19.2 5.0 7.0 5 1 3 8 8 8 2 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.19 PXF44449.1 - 2.3 5.9 72.7 31 2.2 72.7 2.0 1 1 0 1 1 1 0 Myosin tail EzrA PF06160.12 PXF44449.1 - 5 5.2 53.0 0.096 10.9 27.8 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA VWA PF00092.28 PXF44450.1 - 6e-13 49.4 0.1 7.7e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PXF44451.1 - 4.9e-14 52.9 0.0 6.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44451.1 - 2.3e-05 25.0 0.0 4.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF44451.1 - 2.8e-05 23.4 0.3 0.0017 17.6 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 PXF44451.1 - 0.097 12.0 0.1 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein VWA PF00092.28 PXF44452.1 - 1.7e-18 67.5 0.0 2.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44452.1 - 4.4e-10 40.2 0.0 3.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF44452.1 - 0.012 14.8 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Acetyltransf_7 PF13508.7 PXF44453.1 - 5.3e-05 23.6 0.0 9.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF44453.1 - 0.0001 22.2 0.0 0.00028 20.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF44453.1 - 0.00071 19.8 0.0 0.00099 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PXF44453.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein HIT PF01230.23 PXF44453.1 - 0.1 13.3 0.7 2.1 9.1 0.7 2.5 1 1 0 1 1 1 0 HIT domain Acetyltransf_1 PF00583.25 PXF44454.1 - 3.1e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF44454.1 - 6.5e-05 22.9 0.0 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF44454.1 - 0.0005 20.4 0.0 0.00079 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF44454.1 - 0.0027 17.6 0.0 0.0076 16.2 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Peptidase_M3_N PF08439.10 PXF44455.1 - 1.3e-11 44.5 0.1 6.5e-11 42.4 0.1 2.2 1 0 0 1 1 1 1 Oligopeptidase F Peptidase_M3 PF01432.20 PXF44455.1 - 7e-11 42.0 8.0 7.5e-08 32.1 4.0 2.2 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M3_N PF08439.10 PXF44456.1 - 1.4e-11 44.5 0.1 6.5e-11 42.4 0.1 2.2 1 0 0 1 1 1 1 Oligopeptidase F Peptidase_M3 PF01432.20 PXF44456.1 - 1.4e-11 44.3 8.1 1.5e-08 34.3 4.0 2.2 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M20 PF01546.28 PXF44457.1 - 7.4e-19 68.3 1.9 1e-17 64.5 1.9 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF44457.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Oxidored_molyb PF00174.19 PXF44458.1 - 4.7e-56 189.1 0.0 7.5e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PXF44458.1 - 6.9e-37 126.5 0.0 1.2e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 PXF44458.1 - 5.9e-29 100.9 0.0 1.5e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PXF44458.1 - 4.6e-27 94.3 0.0 9.1e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 PXF44458.1 - 8.2e-22 77.1 0.1 1.8e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 PXF44458.1 - 0.0002 21.5 0.0 0.0013 18.9 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain LPMO_10 PF03067.15 PXF44460.1 - 2.5e-14 54.4 0.6 3.4e-14 54.0 0.6 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GMC_oxred_N PF00732.19 PXF44461.1 - 3.2e-36 125.2 0.0 4.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF44461.1 - 3.1e-19 69.9 0.0 5.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 PXF44461.1 - 0.00087 19.0 0.1 0.18 11.3 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF44461.1 - 0.0074 16.5 0.3 0.034 14.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PXF44461.1 - 0.0093 15.1 0.1 0.02 14.0 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 PXF44461.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 PXF44462.1 - 3.1e-36 125.3 0.0 1.4e-35 123.1 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF44462.1 - 1.9e-19 70.6 0.1 3.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 PXF44462.1 - 9.9e-05 22.1 0.0 0.029 14.0 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF44462.1 - 0.00059 19.0 0.0 0.00093 18.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 PXF44462.1 - 0.00066 19.9 0.1 0.0035 17.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PXF44462.1 - 0.024 13.9 0.0 0.083 12.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 PXF44462.1 - 0.03 13.6 0.2 1.8 7.8 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 PXF44462.1 - 0.04 12.8 0.3 0.092 11.6 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 PXF44462.1 - 0.071 12.3 0.0 0.67 9.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2_5 PF13909.6 PXF44463.1 - 0.0012 18.6 2.2 0.028 14.2 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain Lactamase_B PF00753.27 PXF44464.1 - 1.2e-17 64.6 1.9 2.4e-17 63.6 1.9 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF44464.1 - 4.9e-07 29.5 0.5 8.2e-07 28.7 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PXF44464.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Melibiase PF02065.18 PXF44467.1 - 1.7e-138 461.3 0.0 2.2e-138 461.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 PXF44467.1 - 5.7e-67 225.9 0.0 7.5e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 PXF44467.1 - 1.5e-12 47.8 0.0 3.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain Glyco_hydro_31 PF01055.26 PXF44467.1 - 0.0032 16.7 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 BTG PF07742.12 PXF44467.1 - 0.018 14.9 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 BTG family Melibiase_2 PF16499.5 PXF44467.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A XG_FTase PF03254.13 PXF44468.1 - 0.0089 14.7 0.0 0.033 12.8 0.0 1.8 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Aldo_ket_red PF00248.21 PXF44472.1 - 3.2e-40 138.2 0.0 1.7e-38 132.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family YgbA_NO PF11756.8 PXF44472.1 - 0.093 13.1 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter KIX_2 PF16987.5 PXF44473.1 - 7.2e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 KIX domain NPL4 PF05021.15 PXF44474.1 - 2.4e-17 63.3 0.2 1.9e-09 37.3 0.2 3.3 2 1 0 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 PXF44474.1 - 0.00024 21.5 0.0 0.00065 20.1 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.15 PXF44474.1 - 0.00027 21.1 0.1 0.00059 20.0 0.1 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region JAB PF01398.21 PXF44474.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UBX PF00789.20 PXF44474.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 UBX domain SOG2 PF10428.9 PXF44474.1 - 0.29 10.3 6.9 0.38 9.9 6.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 PXF44474.1 - 0.77 9.6 3.8 0.98 9.3 3.8 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 PXF44474.1 - 0.78 8.4 3.8 1.3 7.6 3.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATF7IP_BD PF16788.5 PXF44474.1 - 0.98 9.5 2.6 2 8.5 2.6 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain KAR9 PF08580.10 PXF44474.1 - 4.9 5.6 7.9 6.5 5.2 7.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WD40 PF00400.32 PXF44475.1 - 5.3e-20 71.4 6.3 7.8e-06 26.5 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF44475.1 - 1.5e-05 25.2 0.0 1.7 9.0 0.0 5.0 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF44475.1 - 0.051 12.5 0.8 3.9 6.4 0.0 3.4 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1918 PF08940.11 PXF44475.1 - 0.2 11.3 3.1 0.45 10.2 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Peptidase_S8 PF00082.22 PXF44477.1 - 3.6e-34 118.4 0.0 7.7e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 Subtilase family Ribosomal_S4e PF00900.20 PXF44479.1 - 4.5e-29 100.2 0.1 9e-29 99.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 PXF44479.1 - 2.1e-21 75.7 7.8 2.1e-21 75.7 7.8 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 PXF44479.1 - 2e-20 72.1 0.1 3.4e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 PXF44479.1 - 5.2e-07 29.3 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 PXF44479.1 - 0.0025 17.7 0.3 0.013 15.4 0.3 2.3 1 0 0 1 1 1 1 KOW motif PP2C PF00481.21 PXF44480.1 - 4.5e-43 147.8 0.0 8.2e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF44480.1 - 1.9e-09 37.4 4.6 3.1e-08 33.5 4.6 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PXF44480.1 - 0.00032 20.7 0.1 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Ndc1_Nup PF09531.10 PXF44480.1 - 0.38 9.4 2.5 0.47 9.1 2.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rft-1 PF04506.13 PXF44481.1 - 1.7e-61 208.5 12.4 3e-61 207.7 12.4 1.3 1 1 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 PXF44481.1 - 7.4e-07 28.7 0.6 7.4e-07 28.7 0.6 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Wzz PF02706.15 PXF44481.1 - 1 9.7 5.3 0.39 11.0 0.2 2.7 3 0 0 3 3 3 0 Chain length determinant protein Inositol_P PF00459.25 PXF44482.1 - 2.3e-25 89.6 0.0 4e-25 88.9 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Trypsin PF00089.26 PXF44483.1 - 8.5e-39 133.6 0.0 1.4e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Hint PF01079.20 PXF44483.1 - 9.2e-26 90.7 0.0 1.7e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Hint module SOG2 PF10428.9 PXF44483.1 - 0.035 13.3 9.0 0.05 12.8 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein YajC PF02699.15 PXF44483.1 - 0.035 14.0 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit PFK PF00365.20 PXF44485.1 - 0.0073 15.7 0.4 0.17 11.1 0.0 2.2 1 1 1 2 2 2 2 Phosphofructokinase HipN PF18253.1 PXF44487.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain zf-RING_2 PF13639.6 PXF44488.1 - 3.2e-10 40.2 4.9 6.5e-10 39.2 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PXF44488.1 - 2.5e-09 36.9 3.3 4.9e-09 35.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF44488.1 - 5.7e-09 35.7 4.4 1.2e-08 34.7 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF44488.1 - 3.7e-08 33.5 4.9 9.9e-08 32.2 4.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PXF44488.1 - 1.1e-06 28.6 5.2 2.8e-06 27.3 5.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF44488.1 - 0.00033 20.5 2.0 0.00056 19.7 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF44488.1 - 0.0004 20.1 2.6 0.001 18.7 2.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PXF44488.1 - 0.0004 20.4 2.1 0.00082 19.4 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 PXF44488.1 - 0.00069 19.4 1.7 0.0016 18.3 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 PXF44488.1 - 0.0097 16.0 1.4 0.024 14.7 1.4 1.7 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 PXF44488.1 - 0.042 13.7 8.4 0.66 9.9 7.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RSN1_TM PF13967.6 PXF44488.1 - 0.098 12.4 0.5 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport zf-C3HC4_4 PF15227.6 PXF44488.1 - 0.12 12.6 7.2 0.11 12.6 5.2 2.1 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PXF44488.1 - 0.12 12.4 5.9 0.59 10.1 5.5 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PXF44488.1 - 0.25 11.0 3.5 0.73 9.5 3.5 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PXF44488.1 - 0.49 10.6 4.2 4.7 7.5 4.2 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 PXF44488.1 - 1 9.5 6.4 7.5 6.7 6.2 2.4 1 1 1 2 2 2 0 Zinc-finger Peptidase_M20 PF01546.28 PXF44489.1 - 7.4e-23 81.3 0.4 1.1e-22 80.8 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 PXF44489.1 - 2.1e-07 30.8 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 PXF44489.1 - 9.7e-06 25.5 0.1 9.7e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain DUF656 PF04920.12 PXF44489.1 - 0.092 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF656) PQ-loop PF04193.14 PXF44490.1 - 3.1e-30 103.7 5.3 7e-17 61.0 0.3 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF805 PF05656.14 PXF44490.1 - 0.33 11.4 2.1 0.29 11.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PQ-loop PF04193.14 PXF44491.1 - 4.5e-34 116.0 10.7 5.6e-19 67.7 2.3 2.9 3 0 0 3 3 3 2 PQ loop repeat PAP2 PF01569.21 PXF44495.1 - 0.00025 20.8 0.1 0.00055 19.7 0.1 1.5 1 0 0 1 1 1 1 PAP2 superfamily Pyr_redox_2 PF07992.14 PXF44496.1 - 6.2e-42 143.8 0.0 6.2e-42 143.8 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 PXF44496.1 - 4.6e-20 72.3 0.1 2.7e-13 50.4 0.0 2.3 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 PXF44496.1 - 1.7e-12 47.7 0.3 1.9e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PXF44496.1 - 4.2e-05 23.9 0.2 1.1 9.8 0.0 3.4 3 0 0 3 3 3 2 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 PXF44496.1 - 5.2e-05 22.7 0.0 0.00086 18.7 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF44496.1 - 6.8e-05 22.6 2.3 0.37 10.3 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF44496.1 - 0.00019 21.4 1.9 3.2 7.7 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 PXF44496.1 - 0.011 14.7 2.9 0.079 11.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Keratin_assoc PF09775.9 PXF44496.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 DUF4781 PF16013.5 PXF44496.1 - 6.8 5.4 6.6 0.2 10.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) PAP_fibrillin PF04755.12 PXF44497.1 - 3.8e-29 102.0 0.1 5e-28 98.4 0.1 2.0 1 1 0 1 1 1 1 PAP_fibrillin Atg14 PF10186.9 PXF44498.1 - 0.2 10.7 0.6 0.3 10.1 0.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 C2 PF00168.30 PXF44499.1 - 0.0003 21.0 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain Helicase_C PF00271.31 PXF44500.1 - 1.4e-20 73.7 0.0 8.7e-17 61.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 PXF44500.1 - 4.5e-15 55.8 0.0 2.2e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 PXF44500.1 - 1.7e-06 28.6 0.4 5.1e-06 27.1 0.4 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 PXF44500.1 - 0.00031 20.8 0.0 0.00082 19.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PXF44500.1 - 0.087 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain zf-C2HC_2 PF13913.6 PXF44501.1 - 0.0013 18.6 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF4834 PF16118.5 PXF44502.1 - 0.0003 21.7 0.0 0.00038 21.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) HemY_N PF07219.13 PXF44502.1 - 0.031 14.5 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 HemY protein N-terminus PBS_linker_poly PF00427.21 PXF44503.1 - 1.5e-36 125.2 0.2 2.1e-36 124.7 0.2 1.1 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide DAO PF01266.24 PXF44504.1 - 1.7e-32 113.4 0.2 2e-32 113.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF44504.1 - 2.3e-06 27.7 0.6 2.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PXF44504.1 - 0.002 18.3 1.0 0.0068 16.6 1.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PXF44504.1 - 0.0022 17.3 0.0 0.051 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF44504.1 - 0.27 10.3 1.1 0.39 9.7 0.6 1.5 2 0 0 2 2 2 0 FAD binding domain P5CR_dimer PF14748.6 PXF44506.1 - 6.9e-30 103.3 5.2 1.3e-29 102.4 5.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PXF44506.1 - 3.5e-14 53.1 0.5 4.1e-13 49.7 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 PXF44506.1 - 0.17 11.8 2.0 0.24 11.4 0.2 2.2 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_7 PF13537.6 PXF44507.1 - 2.3e-23 82.4 0.0 3.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PXF44507.1 - 5.3e-23 81.7 0.0 8.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 PXF44507.1 - 2.7e-09 36.8 0.1 4.8e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 PXF44507.1 - 4.8e-07 28.9 0.0 1.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 PXF44507.1 - 0.012 14.3 0.7 1.2 7.8 0.0 2.4 3 0 0 3 3 3 0 Glutamine amidotransferases class-II PRTase_2 PF15609.6 PXF44507.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase zf-C3HC4_3 PF13920.6 PXF44508.1 - 9.4e-13 47.8 9.9 1.4e-12 47.2 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF44508.1 - 3.9e-07 29.8 10.4 7e-07 29.0 10.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PXF44508.1 - 0.00023 21.4 10.7 0.00037 20.8 10.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PXF44508.1 - 0.0026 17.7 10.1 0.0042 17.0 10.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Transcrip_reg PF01709.20 PXF44509.1 - 7.7e-68 228.5 2.4 8.5e-68 228.3 2.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator TYW3 PF02676.14 PXF44509.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase TYW3 LRR_8 PF13855.6 PXF44510.1 - 5.1e-28 96.6 22.2 8.6e-12 44.7 1.6 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PXF44510.1 - 3e-14 52.9 28.9 3.6e-06 27.2 1.9 4.1 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PXF44510.1 - 7.5e-08 32.1 1.5 0.0024 17.4 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PXF44510.1 - 1.5e-07 30.9 13.2 0.3 11.3 0.2 6.4 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 PXF44510.1 - 6.3e-07 29.1 16.1 0.49 11.1 0.1 6.3 5 1 0 5 5 5 3 Leucine Rich Repeat ThiF PF00899.21 PXF44511.1 - 4.1e-65 219.6 0.1 6.6e-65 218.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 PXF44511.1 - 4.2e-22 78.5 2.7 8.1e-22 77.6 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PXF44511.1 - 1e-08 35.5 1.9 4.3e-06 26.8 0.0 2.7 2 1 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 PXF44511.1 - 1.6e-05 25.3 0.1 5.1e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 PXF44511.1 - 0.0075 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 PXF44511.1 - 0.016 15.8 0.2 0.092 13.3 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 PXF44511.1 - 0.028 14.0 0.1 0.16 11.6 0.0 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 PXF44511.1 - 0.041 14.1 0.4 0.17 12.2 0.4 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 PXF44511.1 - 0.051 13.8 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain tRNA-synt_2 PF00152.20 PXF44513.1 - 6.5e-79 265.2 0.0 9.2e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PXF44513.1 - 2.8e-12 46.4 0.2 5.9e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF44513.1 - 0.00063 19.3 0.0 0.7 9.3 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2d PF01409.20 PXF44514.1 - 2.9e-91 305.3 0.1 4e-91 304.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 PXF44514.1 - 2.4e-07 30.4 0.0 8.8e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 PXF44514.1 - 9.7e-07 29.0 0.5 3.1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 PXF44514.1 - 3.2e-05 23.6 0.0 9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA-synt_2 PF00152.20 PXF44514.1 - 5.9e-05 22.3 0.0 0.0002 20.6 0.0 1.7 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF4411 PF14367.6 PXF44514.1 - 0.027 14.4 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) tRNA-synt_2b PF00587.25 PXF44514.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Abhydrolase_1 PF00561.20 PXF44515.1 - 1.7e-15 57.4 0.2 4e-10 39.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF44515.1 - 9.8e-13 47.9 0.1 7.4e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PXF44515.1 - 1.1e-10 41.3 0.0 3.1e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 PXF44515.1 - 2.8e-09 36.1 1.0 0.0013 17.5 0.1 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 PXF44515.1 - 9.8e-09 36.1 0.1 3e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PXF44515.1 - 3.2e-06 27.0 0.1 0.022 14.4 0.0 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 PXF44515.1 - 0.00018 21.5 0.4 0.0007 19.5 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 PXF44515.1 - 0.0031 17.1 0.0 0.035 13.6 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.28 PXF44515.1 - 0.0047 15.8 0.1 0.015 14.2 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family FSH1 PF03959.13 PXF44515.1 - 0.0058 16.3 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 PXF44515.1 - 0.0086 15.4 0.2 2.7 7.2 0.0 2.2 1 1 1 2 2 2 2 Secretory lipase Abhydrolase_4 PF08386.10 PXF44515.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF818 PF05677.12 PXF44515.1 - 0.068 12.1 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 PXF44515.1 - 0.094 12.5 0.1 6.5 6.5 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 PXF44515.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase 6PGD PF00393.19 PXF44516.1 - 1.5e-119 398.7 0.0 2.1e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PXF44516.1 - 7.1e-46 156.3 0.1 1.1e-45 155.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PXF44516.1 - 0.0034 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF44516.1 - 0.0079 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PXF44516.1 - 0.012 16.2 0.0 0.061 13.9 0.0 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PXF44516.1 - 0.044 13.2 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 PXF44516.1 - 0.11 12.7 0.2 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Morc6_S5 PF17942.1 PXF44517.1 - 7.2e-26 90.9 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 PXF44517.1 - 1.4e-08 34.6 3.2 2.9e-08 33.6 3.2 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Ribosomal_L5 PF00281.19 PXF44518.1 - 2.9e-19 69.2 0.0 6.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 PXF44518.1 - 3.8e-19 68.7 0.0 5.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus MMR_HSR1 PF01926.23 PXF44519.1 - 1.2e-20 73.7 0.0 2.8e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF44519.1 - 3.8e-09 36.2 0.0 8.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PXF44519.1 - 1.7e-05 24.8 0.0 0.0042 17.0 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase PPR_2 PF13041.6 PXF44519.1 - 2e-05 24.7 0.0 0.0073 16.5 0.0 3.0 3 0 0 3 3 3 1 PPR repeat family Dynamin_N PF00350.23 PXF44519.1 - 0.00051 20.1 0.0 0.17 11.9 0.1 2.8 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 PXF44519.1 - 0.0075 15.6 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 AIG1 family PPR PF01535.20 PXF44519.1 - 0.0083 16.3 0.0 0.26 11.6 0.1 2.7 2 0 0 2 2 2 1 PPR repeat Tcp11 PF05794.13 PXF44519.1 - 0.015 14.4 6.1 0.037 13.1 6.1 1.6 1 1 0 1 1 1 0 T-complex protein 11 CLPTM1 PF05602.12 PXF44519.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Roc PF08477.13 PXF44519.1 - 0.026 14.8 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PXF44519.1 - 0.048 14.2 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Ras PF00071.22 PXF44519.1 - 0.055 13.1 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Ras family TauD PF02668.16 PXF44520.1 - 1.5e-28 100.4 0.4 4.2e-28 98.9 0.2 1.8 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family GNAT_acetyltr_2 PF13718.6 PXF44521.1 - 9.1e-94 313.1 0.0 1.7e-93 312.2 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PXF44521.1 - 3.7e-60 202.8 0.0 6.8e-60 201.9 0.0 1.5 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 PXF44521.1 - 5.3e-60 203.1 0.0 1.2e-59 201.9 0.0 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 PXF44521.1 - 2.4e-32 110.7 0.0 6.4e-32 109.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 PXF44521.1 - 2.1e-05 24.8 0.1 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF44521.1 - 8.1e-05 22.4 0.2 0.071 12.8 0.0 3.4 4 1 0 4 4 4 2 AAA domain PI-PLC-X PF00388.19 PXF44522.1 - 1e-05 25.2 0.0 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain FAM222A PF15258.6 PXF44522.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A GST_N_3 PF13417.6 PXF44523.1 - 1.5e-10 41.4 0.0 3.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF44523.1 - 1.6e-07 31.3 0.0 3.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PXF44523.1 - 2.1e-07 31.1 0.0 4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PXF44523.1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PXF44523.1 - 0.0023 18.1 0.0 0.053 13.7 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin GST_N PF02798.20 PXF44523.1 - 0.0034 17.7 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PXF44523.1 - 0.025 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PXF44523.1 - 0.072 13.8 0.0 0.35 11.6 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain CRAL_TRIO_2 PF13716.6 PXF44524.1 - 2.1e-06 27.9 0.0 2.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UcrQ PF02939.16 PXF44524.1 - 0.06 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 UcrQ family GIDA PF01134.22 PXF44525.1 - 1.4e-141 472.2 0.0 2e-141 471.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 PXF44525.1 - 1.5e-63 214.8 0.0 2.1e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 PXF44525.1 - 1.5e-07 31.1 1.1 2.4e-07 30.4 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF44525.1 - 7.7e-07 28.5 6.0 0.00022 20.4 2.6 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PXF44525.1 - 2.5e-05 23.6 0.9 2.5e-05 23.6 0.9 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PXF44525.1 - 3.8e-05 23.1 0.3 7e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 PXF44525.1 - 0.00011 22.7 0.4 0.00024 21.6 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF44525.1 - 0.00067 18.5 1.5 0.0087 14.8 1.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 PXF44525.1 - 0.0046 16.6 2.1 0.18 11.3 0.4 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PXF44525.1 - 0.0059 15.9 0.2 0.019 14.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PXF44525.1 - 0.042 14.1 1.3 0.098 12.9 1.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PXF44525.1 - 0.058 12.4 1.1 0.12 11.4 0.8 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 PXF44525.1 - 0.18 11.0 0.2 0.3 10.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family DUF155 PF02582.14 PXF44526.1 - 1.7e-39 135.7 0.0 2.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RepA1_leader PF08048.12 PXF44526.1 - 0.47 10.8 3.6 23 5.4 1.1 2.6 2 0 0 2 2 2 0 Tap RepA1 leader peptide mRNA_triPase PF02940.15 PXF44527.1 - 8.5e-30 104.1 5.4 1.1e-29 103.7 5.4 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain TRAM_LAG1_CLN8 PF03798.16 PXF44528.1 - 7e-26 91.2 21.0 7e-26 91.2 21.0 2.1 1 1 1 2 2 2 1 TLC domain Rad60-SLD PF11976.8 PXF44529.1 - 3.8e-11 42.6 0.1 9.2e-11 41.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like AT_hook PF02178.19 PXF44529.1 - 0.046 13.6 2.3 0.13 12.2 2.3 1.9 1 0 0 1 1 1 0 AT hook motif PMSI1 PF15322.6 PXF44529.1 - 0.052 13.0 2.9 0.068 12.6 2.9 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative PDZ_3 PF17815.1 PXF44530.1 - 2.2e-33 115.2 0.0 3.7e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PXF44530.1 - 3e-17 63.9 0.0 5.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF44530.1 - 5e-12 46.1 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PXF44530.1 - 4.8e-07 30.0 0.0 1.9e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S7 PF00949.21 PXF44530.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 PXF44530.1 - 0.0022 16.7 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase S46 PDZ PF00595.24 PXF44530.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_1 PF12812.7 PXF44530.1 - 0.02 14.9 0.0 2 8.5 0.0 3.2 3 0 0 3 3 3 0 PDZ-like domain COG7 PF10191.9 PXF44530.1 - 0.081 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) PDZ_6 PF17820.1 PXF44530.1 - 0.15 11.9 0.1 17 5.3 0.0 2.9 3 0 0 3 3 3 0 PDZ domain MutS_V PF00488.21 PXF44531.1 - 1.1e-78 263.6 0.2 2.4e-78 262.5 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PXF44531.1 - 4.6e-32 111.8 3.1 1.1e-31 110.5 1.8 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 PXF44531.1 - 7.5e-13 48.7 0.4 1.9e-12 47.3 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PXF44531.1 - 1e-07 32.3 1.2 3.4e-06 27.4 0.1 2.9 2 0 0 2 2 2 1 MutS domain II CREPT PF16566.5 PXF44531.1 - 1.6 8.9 4.0 0.87 9.8 0.1 2.6 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour Zn_ribbon_SprT PF17283.2 PXF44532.1 - 0.012 15.6 0.2 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF1127 PF06568.11 PXF44533.1 - 0.081 12.7 0.6 0.12 12.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Gpr1_Fun34_YaaH PF01184.19 PXF44534.1 - 7.1e-22 78.0 10.3 9.5e-22 77.6 10.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Phage_r1t_holin PF16945.5 PXF44534.1 - 0.043 14.0 0.4 0.1 12.8 0.4 1.7 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin ubiquitin PF00240.23 PXF44535.1 - 1.2e-11 44.2 0.0 2.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family FKBP_N PF01346.18 PXF44535.1 - 4.7e-07 30.7 0.2 1.2e-06 29.4 0.0 1.8 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Rad60-SLD PF11976.8 PXF44535.1 - 5.1e-07 29.4 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FKBP_C PF00254.28 PXF44535.1 - 0.00011 22.5 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase STI1 PF17830.1 PXF44535.1 - 0.09 12.7 1.8 4.3 7.3 0.1 2.6 1 1 1 2 2 2 0 STI1 domain TBK1_ULD PF18396.1 PXF44535.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain HEAT PF02985.22 PXF44536.1 - 1.3e-38 127.7 24.6 0.0063 16.7 0.0 14.0 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 PXF44536.1 - 4.5e-31 107.1 5.5 6.7e-08 32.8 0.0 6.9 4 2 3 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 PXF44536.1 - 2.4e-11 44.0 1.4 0.21 12.2 0.0 7.7 5 3 3 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 PXF44536.1 - 6e-09 36.2 5.5 0.00032 21.1 0.1 6.8 6 2 1 7 7 7 1 HEAT-like repeat Cnd1 PF12717.7 PXF44536.1 - 4.3e-07 30.1 5.9 0.091 12.8 0.1 5.0 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PXF44536.1 - 1.5e-06 27.1 3.2 0.097 11.2 0.1 4.6 4 1 1 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 PXF44536.1 - 0.034 14.3 3.9 2.9 8.1 0.1 4.3 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2972 PF11186.8 PXF44536.1 - 0.038 13.9 0.1 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2972) DUF4042 PF13251.6 PXF44536.1 - 0.056 13.1 0.7 24 4.5 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) RICTOR_V PF14668.6 PXF44536.1 - 0.089 13.0 0.0 1.9 8.8 0.0 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 IFRD PF05004.13 PXF44536.1 - 0.15 11.1 0.9 7.9 5.5 0.1 3.3 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) FAD_binding_4 PF01565.23 PXF44537.1 - 7.7e-12 45.1 0.1 1.2e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Dala_Dala_lig_C PF07478.13 PXF44538.1 - 1.3e-47 162.0 0.0 1e-18 67.6 0.0 4.2 4 0 0 4 4 4 4 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 PXF44538.1 - 3.8e-43 146.1 0.0 3.5e-20 72.4 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase N-terminus ATP-grasp_3 PF02655.14 PXF44538.1 - 5.6e-05 23.2 0.0 2.1 8.4 0.0 3.6 4 0 0 4 4 4 2 ATP-grasp domain ATP-grasp_4 PF13535.6 PXF44538.1 - 0.0001 22.0 0.0 0.069 12.7 0.0 3.5 3 0 0 3 3 3 1 ATP-grasp domain Cys_Met_Meta_PP PF01053.20 PXF44539.1 - 5.2e-102 341.2 0.0 5.8e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PXF44539.1 - 2.1e-07 30.5 0.0 3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PXF44539.1 - 1.9e-05 23.8 0.0 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 PXF44539.1 - 0.00019 20.1 0.0 0.00053 18.6 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 PXF44539.1 - 0.0009 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Chromo PF00385.24 PXF44540.1 - 4.9e-07 29.6 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ATC_hydrolase PF14196.6 PXF44542.1 - 0.058 14.2 0.1 0.082 13.7 0.1 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase TFIIB PF00382.19 PXF44543.1 - 1.3e-24 86.0 1.8 4.3e-13 49.1 0.1 3.3 3 0 0 3 3 3 3 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 PXF44543.1 - 4.9e-11 42.0 0.7 8.5e-11 41.2 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4_2 PF08281.12 PXF44543.1 - 2e-06 27.4 0.2 0.013 15.2 0.1 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 MarR_2 PF12802.7 PXF44543.1 - 0.027 14.4 0.0 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 MarR family Cyclin_C PF02984.19 PXF44543.1 - 0.054 13.6 0.1 9.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain HTH_AsnC-type PF13404.6 PXF44543.1 - 0.092 12.6 0.0 11 6.0 0.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Pox_ATPase-GT PF10640.9 PXF44543.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase HTH_20 PF12840.7 PXF44543.1 - 0.12 12.4 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sec5 PF15469.6 PXF44543.1 - 0.16 11.8 0.0 5.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cyclin_N PF00134.23 PXF44543.1 - 0.17 11.6 1.9 0.53 10.0 0.1 2.3 3 0 0 3 3 3 0 Cyclin, N-terminal domain TniQ PF06527.11 PXF44543.1 - 0.19 12.5 1.1 28 5.4 0.1 3.3 2 1 1 3 3 3 0 TniQ DUF2387 PF09526.10 PXF44543.1 - 1.5 9.0 3.6 3.4 7.9 0.8 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.10 PXF44543.1 - 2.3 8.4 4.6 1.4 9.1 0.9 2.3 1 1 1 2 2 2 0 Zinc ribbon domain GLTSCR1 PF15249.6 PXF44544.1 - 9.4e-09 35.6 1.4 3.3e-08 33.9 0.1 2.8 2 1 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein GlutR_N PF05201.15 PXF44545.1 - 7.2e-41 139.4 0.3 1.2e-40 138.6 0.3 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 PXF44545.1 - 6.6e-39 133.1 0.1 1.6e-38 131.9 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 PXF44545.1 - 6.2e-23 81.1 1.0 6.2e-23 81.1 1.0 1.8 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 PXF44545.1 - 8.4e-08 32.7 0.1 5.3e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 PXF44545.1 - 8e-07 28.3 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 PXF44545.1 - 0.003 17.8 0.0 0.0084 16.4 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 PXF44545.1 - 0.051 14.0 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding zf-Tim10_DDP PF02953.15 PXF44546.1 - 5.3e-17 61.2 0.4 6.6e-17 60.9 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CHAD PF05235.14 PXF44547.1 - 0.06 13.3 4.0 0.14 12.1 4.0 1.8 1 1 0 1 1 1 0 CHAD domain Ras PF00071.22 PXF44549.1 - 2.5e-25 89.0 0.0 8.1e-22 77.5 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.12 PXF44549.1 - 1.5e-23 82.6 0.0 5e-23 80.9 0.0 1.9 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 PXF44549.1 - 3.9e-15 56.1 0.0 1.4e-14 54.3 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PXF44549.1 - 2.3e-08 34.1 0.9 7.5e-08 32.5 0.3 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PXF44549.1 - 9.4e-08 31.8 0.4 3.4e-06 26.7 0.1 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 PXF44549.1 - 7.7e-07 28.6 1.0 0.051 13.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF_assoc_1 PF08355.12 PXF44549.1 - 2.1e-06 27.2 0.0 6.7e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 EF hand associated Dynamin_N PF00350.23 PXF44549.1 - 2.2e-06 27.9 2.9 0.02 15.0 0.3 2.4 1 1 1 2 2 2 2 Dynamin family EF-hand_1 PF00036.32 PXF44549.1 - 2.3e-06 26.8 1.3 0.042 13.4 0.0 2.8 2 0 0 2 2 2 2 EF hand SRPRB PF09439.10 PXF44549.1 - 4.8e-05 22.9 0.4 0.00023 20.7 0.1 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit EF-hand_7 PF13499.6 PXF44549.1 - 7.2e-05 23.2 0.5 0.52 10.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 PXF44549.1 - 8.4e-05 22.1 0.1 0.00028 20.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_5 PF13202.6 PXF44549.1 - 0.00061 19.2 1.6 0.0036 16.7 0.0 2.8 2 0 0 2 2 2 1 EF hand AIG1 PF04548.16 PXF44549.1 - 0.014 14.7 0.2 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 AIG1 family EF-hand_10 PF14788.6 PXF44549.1 - 0.089 12.7 0.5 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 EF hand FeoB_N PF02421.18 PXF44549.1 - 0.12 11.9 0.4 0.24 10.9 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 PXF44549.1 - 0.15 11.4 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 PXF44549.1 - 0.16 11.4 0.1 0.4 10.1 0.1 1.7 1 1 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 PXF44549.1 - 0.29 11.0 1.7 2.4 8.0 0.1 2.9 2 1 1 3 3 3 0 RsgA GTPase TB2_DP1_HVA22 PF03134.19 PXF44550.1 - 3.6e-15 55.7 8.6 1.6e-14 53.5 1.7 3.2 4 0 0 4 4 4 2 TB2/DP1, HVA22 family DUF3727 PF12527.8 PXF44551.1 - 7.2e-12 45.4 11.8 1.3e-07 31.8 7.1 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3727) Chromo_2 PF18704.1 PXF44551.1 - 0.07 13.4 1.6 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 FAM176 PF14851.6 PXF44551.1 - 0.45 10.2 3.9 0.21 11.3 1.4 1.8 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 PXF44551.1 - 1.4 8.3 7.7 1.6 8.1 7.7 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 PXF44551.1 - 1.7 7.7 14.4 2.7 7.1 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 PXF44551.1 - 2.2 6.4 10.3 2.6 6.1 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 PXF44551.1 - 5.1 6.3 7.0 5.6 6.2 7.0 1.1 1 0 0 1 1 1 0 BUD22 HhH-GPD PF00730.25 PXF44552.1 - 5.8e-07 29.9 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HD_4 PF13328.6 PXF44552.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 HD domain PQ-loop PF04193.14 PXF44553.1 - 5.9e-08 32.4 1.7 0.0006 19.5 0.3 3.1 4 0 0 4 4 4 2 PQ loop repeat NADH_B2 PF14813.6 PXF44553.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 DUF4418 PF14387.6 PXF44553.1 - 0.25 11.6 3.4 0.091 13.0 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF202 PF02656.15 PXF44553.1 - 2.1 8.8 9.0 2.4 8.7 3.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) zf-U11-48K PF05253.12 PXF44554.1 - 2.3e-06 27.4 1.9 3.7e-06 26.7 1.9 1.3 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Ribosomal_L19e PF01280.20 PXF44556.1 - 3.2e-61 205.6 5.9 3.2e-61 205.6 5.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L19e IBR PF01485.21 PXF44557.1 - 2.8e-06 27.5 8.9 2.8e-06 27.5 8.9 2.9 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-UDP PF14569.6 PXF44557.1 - 6.9 6.9 12.1 1.3 9.2 2.1 2.6 2 1 1 3 3 3 0 Zinc-binding RING-finger ECH_2 PF16113.5 PXF44559.1 - 9.5e-70 235.7 0.0 1.1e-69 235.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PXF44559.1 - 3.2e-19 69.2 0.4 1.1e-18 67.5 0.3 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 PXF44560.1 - 5.1e-21 75.2 0.0 9.4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF44560.1 - 7.8e-13 48.7 0.0 1.8e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PXF44560.1 - 2.6e-05 23.5 0.0 4.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 PXF44560.1 - 0.012 15.7 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain SmpB PF01668.18 PXF44561.1 - 2.7e-51 173.2 1.6 3.2e-51 173.0 1.6 1.0 1 0 0 1 1 1 1 SmpB protein RRM_2 PF04059.12 PXF44562.1 - 3.4e-44 149.0 0.2 5.5e-44 148.3 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 PXF44562.1 - 4.4e-23 80.9 0.0 1.6e-11 43.9 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF44562.1 - 4.3e-08 32.8 0.0 1.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PXF44562.1 - 1.9e-05 24.4 0.0 0.0015 18.3 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif BRAP2 PF07576.12 PXF44562.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 PXF44562.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Smg-4/UPF3 family Ribonuc_L-PSP PF01042.21 PXF44563.1 - 4.1e-14 52.6 0.1 5.9e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP LRR_4 PF12799.7 PXF44564.1 - 4.1e-10 39.8 7.4 0.0019 18.6 0.4 6.2 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PXF44564.1 - 2e-05 24.3 12.0 4.3e-05 23.2 1.8 4.2 4 0 0 4 4 4 2 Leucine rich repeat zf-HC5HC2H PF13771.6 PXF44564.1 - 0.21 11.9 0.8 0.39 11.0 0.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PRKCSH_1 PF13015.6 PXF44566.1 - 4.4e-33 114.2 1.2 4.4e-33 114.2 1.2 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 PXF44566.1 - 4.9e-28 98.1 4.9 4.9e-28 98.1 4.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 PXF44566.1 - 0.0014 19.5 0.6 0.0076 17.2 0.6 2.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 PXF44566.1 - 0.0019 18.4 14.5 0.0025 18.0 4.8 2.8 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A DUF4349 PF14257.6 PXF44566.1 - 0.093 12.2 2.0 0.18 11.2 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF5082 PF16888.5 PXF44566.1 - 0.097 13.0 0.2 0.097 13.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) ATG27 PF09451.10 PXF44566.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.1 2 1 0 2 2 2 0 Autophagy-related protein 27 GTP-bdg_M PF16360.5 PXF44566.1 - 0.92 10.1 5.7 6.9 7.3 0.0 2.4 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Myb_DNA-binding PF00249.31 PXF44567.1 - 4.7e-11 42.7 0.0 0.00054 20.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF44567.1 - 0.00021 21.4 1.0 0.092 13.0 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF44567.1 - 0.0051 16.7 0.3 0.02 14.7 0.3 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Semialdhyde_dhC PF02774.18 PXF44568.1 - 5.3e-35 121.1 0.0 9.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 PXF44568.1 - 3.4e-30 105.0 0.0 7e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 PXF44568.1 - 0.00056 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 PXF44568.1 - 0.044 13.9 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cytochrome-c551 PF10643.9 PXF44568.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Gp_dh_C PF02800.20 PXF44568.1 - 0.12 12.0 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain NAD_binding_10 PF13460.6 PXF44568.1 - 0.18 11.7 0.0 0.44 10.4 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding CH PF00307.31 PXF44569.1 - 8.6e-16 58.1 0.1 7.8e-06 26.0 0.0 4.5 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PXF44569.1 - 0.00057 19.7 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain Vfa1 PF08432.10 PXF44571.1 - 1.9 8.8 10.2 2.7 8.3 10.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Acetyltransf_1 PF00583.25 PXF44572.1 - 5.6e-06 26.6 0.0 9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PXF44572.1 - 5e-05 23.2 0.0 9.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 PXF44572.1 - 0.0019 18.9 0.0 0.0039 17.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF44572.1 - 0.0035 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PXF44572.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 PXF44572.1 - 0.019 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF44572.1 - 0.035 14.5 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3017 PF11222.8 PXF44572.1 - 0.11 12.8 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) PanZ PF12568.8 PXF44572.1 - 0.12 12.0 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ SBF PF01758.16 PXF44573.1 - 5.4e-32 111.0 17.7 5.4e-32 111.0 17.7 1.7 1 1 1 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 PXF44573.1 - 5e-15 55.6 26.3 6.2e-15 55.3 26.3 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Pam17 PF08566.10 PXF44573.1 - 2.5 8.0 7.0 0.87 9.4 1.7 2.2 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 Pkinase PF00069.25 PXF44574.1 - 1.1e-34 120.0 0.0 1.9e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44574.1 - 1.1e-19 70.8 0.0 2e-19 69.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase F420_oxidored PF03807.17 PXF44575.1 - 2.8e-09 37.4 3.4 1.3e-06 28.9 3.4 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ferric_reduct PF01794.19 PXF44575.1 - 0.0012 18.9 2.8 0.0012 18.9 2.8 2.8 1 1 2 3 3 3 1 Ferric reductase like transmembrane component NAD_Gly3P_dh_N PF01210.23 PXF44575.1 - 0.0015 18.6 1.3 0.18 11.8 0.1 2.3 1 1 1 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 PXF44575.1 - 0.01 16.0 0.2 0.29 11.3 0.2 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 PXF44575.1 - 0.023 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 PXF44575.1 - 0.025 14.8 0.1 0.11 12.7 0.1 2.0 1 1 0 1 1 1 0 TrkA-N domain PDH PF02153.17 PXF44575.1 - 0.072 12.1 0.3 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase ABC_ATPase PF09818.9 PXF44577.1 - 2.3e-173 577.1 0.0 1e-171 571.7 0.0 2.0 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 PXF44577.1 - 0.0055 16.3 0.0 0.018 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 PXF44577.1 - 0.0074 16.8 0.1 0.082 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 PXF44577.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MqsR_toxin PF15723.5 PXF44577.1 - 0.075 13.4 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Pkinase PF00069.25 PXF44578.1 - 4e-73 246.0 0.0 4.7e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44578.1 - 4.1e-30 104.9 0.0 6.7e-30 104.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PXF44578.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PXF44578.1 - 0.0023 17.3 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF44578.1 - 0.0096 14.9 0.0 0.018 14.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF44578.1 - 0.057 12.8 0.0 0.19 11.0 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF44578.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family O-FucT PF10250.9 PXF44579.1 - 4e-09 36.6 0.0 4.9e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4948 PF16306.5 PXF44579.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) Glyco_tranf_2_4 PF13704.6 PXF44580.1 - 2.1e-08 34.6 0.1 5e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PXF44580.1 - 1.5e-06 28.0 0.6 2.3e-06 27.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 O-FucT PF10250.9 PXF44581.1 - 1.4e-21 77.6 0.1 2.3e-21 76.9 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CTP_transf_3 PF02348.19 PXF44582.1 - 3.2e-26 92.6 0.0 4.1e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 PXF44582.1 - 2e-05 25.0 0.0 3.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 PXF44582.1 - 0.03 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BolA PF01722.18 PXF44583.1 - 4.9e-16 58.8 0.0 1.4e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Stk19 PF10494.9 PXF44584.1 - 7.8e-31 107.6 0.0 1.8e-30 106.4 0.0 1.6 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 CMS1 PF14617.6 PXF44585.1 - 5e-11 42.4 0.0 5e-11 42.4 0.0 3.3 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Serinc PF03348.15 PXF44585.1 - 2 7.2 6.7 2.9 6.7 6.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) V-ATPase_C PF03223.15 PXF44587.1 - 3.9e-109 365.4 0.1 4.4e-109 365.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NTP_transf_3 PF12804.7 PXF44588.1 - 2.2e-13 50.9 0.1 3.9e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 PXF44588.1 - 2.2e-09 37.3 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase GHMP_kinases_N PF00288.26 PXF44588.1 - 1.6e-07 31.4 0.0 4.2e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PXF44588.1 - 0.00069 19.9 0.0 0.0031 17.8 0.0 2.2 1 1 0 1 1 1 1 GHMP kinases C terminal IspD PF01128.19 PXF44588.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Acetyltransf_1 PF00583.25 PXF44589.1 - 1.6e-13 50.9 0.0 2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF44589.1 - 1e-07 32.3 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF44589.1 - 3.5e-07 30.2 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PXF44589.1 - 0.006 16.7 0.0 0.0082 16.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PXF44589.1 - 0.036 14.2 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TspO_MBR PF03073.15 PXF44590.1 - 5e-21 75.2 17.5 6e-21 74.9 17.5 1.1 1 0 0 1 1 1 1 TspO/MBR family TspO_MBR PF03073.15 PXF44591.1 - 2.6e-27 95.5 16.6 3.2e-27 95.2 16.6 1.1 1 0 0 1 1 1 1 TspO/MBR family SUIM_assoc PF16619.5 PXF44591.1 - 0.45 10.6 9.5 0.69 10.0 9.5 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LON_substr_bdg PF02190.16 PXF44593.1 - 7.7e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain FUSC PF04632.12 PXF44593.1 - 0.05 12.1 1.0 0.076 11.5 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rav1p_C PF12234.8 PXF44595.1 - 1.6e-43 149.1 1.9 2.4e-43 148.5 1.9 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 PXF44595.1 - 1.1e-12 48.3 25.4 0.0041 17.9 0.0 10.1 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF44595.1 - 9.2e-06 25.9 0.3 1.5 9.2 0.0 6.0 4 3 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4598 PF15370.6 PXF44596.1 - 0.0039 17.6 2.4 0.0042 17.5 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Pectate_lyase PF03211.13 PXF44599.1 - 0.038 13.5 0.0 0.098 12.2 0.0 1.6 2 0 0 2 2 2 0 Pectate lyase CSN8_PSD8_EIF3K PF10075.9 PXF44600.1 - 1.9e-23 83.0 0.0 3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Hint PF01079.20 PXF44601.1 - 6.6e-23 81.3 0.0 1.3e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Hint module Endothelin PF00322.17 PXF44601.1 - 0.44 10.2 2.1 1.2 8.8 2.1 1.7 1 0 0 1 1 1 0 Endothelin family TauE PF01925.19 PXF44602.1 - 4.1e-19 69.1 18.5 5.6e-19 68.7 18.5 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PIF1 PF05970.14 PXF44603.1 - 0.022 14.0 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase zf-C2H2 PF00096.26 PXF44604.1 - 7.6e-12 45.0 25.9 0.00028 21.2 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF44604.1 - 8.2e-10 38.7 25.1 0.0074 17.0 1.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF44604.1 - 2.3e-05 24.6 21.9 0.031 14.7 0.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 PXF44604.1 - 9.8e-05 22.3 1.0 9.8e-05 22.3 1.0 4.6 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF44604.1 - 0.00013 22.2 12.0 0.016 15.5 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PXF44604.1 - 0.00051 19.7 4.5 0.00051 19.7 4.5 3.8 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-BED PF02892.15 PXF44604.1 - 0.078 13.0 1.2 0.078 13.0 1.2 4.1 2 1 1 3 3 2 0 BED zinc finger zf-Di19 PF05605.12 PXF44604.1 - 0.16 12.3 0.1 0.16 12.3 0.1 3.5 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 PXF44604.1 - 0.19 12.4 7.0 2.9 8.6 1.0 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 PXF44604.1 - 0.29 11.6 11.2 1.8 9.1 0.8 3.4 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PXF44604.1 - 0.82 10.0 19.0 4.1 7.8 0.5 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.15 PXF44604.1 - 2.8 8.2 7.1 15 5.9 0.2 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain HNH_5 PF14279.6 PXF44604.1 - 3.9 7.4 13.0 1.3 9.0 0.6 3.6 1 1 3 4 4 4 0 HNH endonuclease zf-C2H2_11 PF16622.5 PXF44604.1 - 4.5 7.1 19.1 3 7.7 0.5 4.3 4 0 0 4 4 4 0 zinc-finger C2H2-type ADK_lid PF05191.14 PXF44604.1 - 5.4 7.1 16.2 2.4 8.2 3.5 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 PXF44605.1 - 1.5e-15 56.6 38.8 0.00043 20.6 1.1 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF44605.1 - 1.5e-14 53.4 38.1 0.0039 17.9 1.1 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF44605.1 - 3.3e-09 36.7 34.5 0.046 14.2 0.3 7.0 7 0 0 7 7 7 4 Zinc-finger double domain zf-Di19 PF05605.12 PXF44605.1 - 3.9e-06 27.1 1.0 3.9e-06 27.1 1.0 4.2 2 2 2 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PXF44605.1 - 7.1e-05 23.0 20.9 0.0042 17.3 0.3 6.0 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 PXF44605.1 - 0.0003 20.7 0.7 0.0003 20.7 0.7 5.5 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PXF44605.1 - 0.00098 18.8 2.3 0.00098 18.8 2.3 5.9 6 1 0 6 6 5 1 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 PXF44605.1 - 0.0012 19.6 13.4 0.002 18.8 4.0 3.1 2 2 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats ADK_lid PF05191.14 PXF44605.1 - 0.052 13.5 17.7 0.77 9.8 1.9 4.2 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 PXF44605.1 - 0.38 10.5 28.5 1.9 8.4 0.3 6.1 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-RING_7 PF02591.15 PXF44605.1 - 1.8 8.8 17.1 18 5.6 0.2 5.2 5 0 0 5 5 5 0 C4-type zinc ribbon domain Desulfoferrod_N PF06397.12 PXF44605.1 - 2.2 8.0 9.0 2.9 7.6 0.1 3.6 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.10 PXF44605.1 - 6.1 7.0 23.1 4.4 7.5 3.4 4.4 3 1 1 4 4 4 0 Zinc ribbon domain zf-met PF12874.7 PXF44605.1 - 8.5 6.9 20.2 8.1 7.0 0.3 5.3 7 0 0 7 7 6 0 Zinc-finger of C2H2 type BssB_TutG PF18512.1 PXF44606.1 - 0.14 12.1 0.7 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit NAM-associated PF14303.6 PXF44609.1 - 3.3 8.4 9.0 1.1 9.9 4.2 2.5 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Abhydrolase_1 PF00561.20 PXF44610.1 - 1.2e-23 84.1 0.0 3.8e-20 72.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF44610.1 - 1.3e-10 41.0 0.0 4.3e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF44610.1 - 3.6e-08 34.3 0.3 5e-08 33.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PXF44610.1 - 0.012 15.2 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ABC_tran PF00005.27 PXF44614.1 - 5.4e-25 88.5 0.0 9.7e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF44614.1 - 7.3e-11 42.4 0.5 3.2e-06 27.2 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PXF44614.1 - 0.00056 20.6 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) RecA PF00154.21 PXF44614.1 - 0.042 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SPOR PF05036.13 PXF44614.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Sporulation related domain TPR_2 PF07719.17 PXF44615.1 - 0.00053 19.9 0.3 2.3 8.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF44615.1 - 0.14 13.1 7.7 1.3 10.0 0.1 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat RXLR PF16810.5 PXF44615.1 - 9.7 6.6 7.2 3.8 7.9 0.5 2.9 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Ribosomal_L5e PF17144.4 PXF44616.1 - 1e-82 276.0 0.3 1.8e-82 275.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 PXF44616.1 - 5.4e-31 107.4 4.3 5.4e-31 107.4 4.3 2.2 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4756 PF15948.5 PXF44616.1 - 0.065 13.1 0.1 0.065 13.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) PRA1 PF03208.19 PXF44617.1 - 3.7e-23 81.7 3.9 4.7e-23 81.4 3.9 1.0 1 0 0 1 1 1 1 PRA1 family protein O-antigen_lig PF13425.6 PXF44617.1 - 0.21 10.4 12.4 0.26 10.0 12.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hemerythrin PF01814.23 PXF44618.1 - 6e-29 101.3 9.9 1.7e-10 41.6 0.5 4.4 3 1 0 3 3 3 3 Hemerythrin HHE cation binding domain zf-CHY PF05495.12 PXF44618.1 - 4.5e-18 65.5 21.6 4.5e-18 65.5 21.6 4.6 2 1 0 2 2 2 1 CHY zinc finger zinc_ribbon_6 PF14599.6 PXF44618.1 - 1.4e-17 63.5 2.5 1.4e-17 63.5 2.5 4.0 3 0 0 3 3 3 1 Zinc-ribbon zf-RING_2 PF13639.6 PXF44618.1 - 1e-07 32.2 5.5 1e-07 32.2 5.5 6.4 4 1 2 6 6 6 1 Ring finger domain zf-C3HC4 PF00097.25 PXF44618.1 - 1.9e-05 24.4 6.0 1.9e-05 24.4 6.0 4.9 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF44618.1 - 2.7e-05 24.1 6.2 2.7e-05 24.1 6.2 5.6 2 1 2 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF44618.1 - 5.4e-05 23.1 4.2 5.4e-05 23.1 4.2 4.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PXF44618.1 - 9e-05 22.2 5.9 9e-05 22.2 5.9 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF44618.1 - 0.00012 21.9 0.8 0.00012 21.9 0.8 5.9 5 2 2 7 7 7 2 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 PXF44618.1 - 0.039 13.8 10.6 3.9 7.4 0.1 5.4 5 0 0 5 5 5 0 Rad50 zinc hook motif FHA PF00498.26 PXF44619.1 - 2.6e-11 43.7 0.3 1.3e-10 41.5 0.0 2.2 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PXF44619.1 - 0.00087 19.6 0.0 0.0035 17.6 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Inositol_P PF00459.25 PXF44620.1 - 1.2e-51 175.8 0.0 1.5e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family CAP_N PF01213.19 PXF44621.1 - 8.9e-19 68.1 0.4 7.3e-16 58.5 0.1 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal TipAS PF07739.13 PXF44621.1 - 0.0015 19.1 1.0 0.4 11.2 0.0 2.6 3 0 0 3 3 3 2 TipAS antibiotic-recognition domain Phage_Mu_Gam PF07352.12 PXF44621.1 - 0.011 15.7 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein INTS2 PF14750.6 PXF44621.1 - 0.016 12.8 0.2 0.022 12.4 0.2 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 SPO22 PF08631.10 PXF44621.1 - 0.035 13.6 0.4 0.067 12.7 0.4 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Cep57_CLD_2 PF14197.6 PXF44621.1 - 0.099 12.7 0.6 0.27 11.3 0.6 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CAP_N PF01213.19 PXF44622.1 - 8.4e-146 485.5 7.1 4e-47 161.2 0.1 4.0 1 1 3 4 4 4 4 Adenylate cyclase associated (CAP) N terminal BAAT_C PF08840.11 PXF44622.1 - 1.4e-07 31.7 3.7 0.0073 16.2 0.0 3.7 4 0 0 4 4 4 3 BAAT / Acyl-CoA thioester hydrolase C terminal Closter_coat PF01785.17 PXF44622.1 - 0.00018 20.8 0.8 0.11 11.8 0.0 3.3 3 0 0 3 3 3 1 Closterovirus coat protein TBCA PF02970.16 PXF44622.1 - 0.039 14.3 2.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Tubulin binding cofactor A DUF1805 PF08827.11 PXF44622.1 - 0.045 14.1 0.7 1.9e+02 2.5 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1805) DUF4905 PF16248.5 PXF44622.1 - 0.062 13.2 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4905) F-actin_cap_A PF01267.17 PXF44622.1 - 0.23 10.9 2.5 21 4.4 0.1 3.1 3 0 0 3 3 3 0 F-actin capping protein alpha subunit Shal-type PF11601.8 PXF44622.1 - 0.81 9.3 4.0 15 5.3 0.2 3.0 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels, N-terminal Apolipoprotein PF01442.18 PXF44622.1 - 1.2 9.0 4.3 41 4.0 0.0 3.7 4 2 0 4 4 4 0 Apolipoprotein A1/A4/E domain Ribosomal_L30_N PF08079.12 PXF44622.1 - 2.3 8.5 12.8 8.8 6.7 1.0 4.1 4 0 0 4 4 4 0 Ribosomal L30 N-terminal domain UPF0225 PF17775.1 PXF44623.1 - 1.8e-06 28.7 0.0 1.9e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 UPF0225 domain RHSP PF07999.11 PXF44624.1 - 0.00016 20.6 0.2 0.00043 19.2 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon hot spot protein AMP_N PF05195.16 PXF44624.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Pkinase PF00069.25 PXF44626.1 - 3.4e-65 220.1 0.0 4e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44626.1 - 1.6e-31 109.5 0.0 2.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF44626.1 - 0.00028 20.0 0.0 0.00038 19.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PXF44626.1 - 0.095 12.6 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PSII_Pbs27 PF13326.6 PXF44627.1 - 6.5e-25 88.1 0.0 8.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Photosystem II Pbs27 Mito_carr PF00153.27 PXF44628.1 - 3.7e-67 222.3 0.6 4.9e-24 84.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 PXF44629.1 - 3.5e-14 53.0 6.2 9.6e-06 26.3 0.2 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF44629.1 - 3.1e-05 24.2 0.2 0.21 11.9 0.0 5.0 4 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PXF44629.1 - 0.017 13.8 0.2 0.24 10.0 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PXF44629.1 - 0.27 11.8 4.9 0.43 11.1 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain SPX PF03105.19 PXF44630.1 - 9.8e-23 81.7 22.8 2.9e-12 47.2 0.6 4.0 2 1 2 4 4 4 3 SPX domain FAM76 PF16046.5 PXF44630.1 - 0.26 10.6 2.4 0.38 10.0 2.4 1.2 1 0 0 1 1 1 0 FAM76 protein INO80_Ies4 PF08193.11 PXF44630.1 - 2.6 8.0 7.9 0.95 9.4 1.2 2.3 2 0 0 2 2 2 0 INO80 complex subunit Ies4 HAUS4 PF14735.6 PXF44631.1 - 6.8e-19 68.5 3.4 1.4e-18 67.5 2.9 1.8 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 4 RNA_pol PF00940.19 PXF44632.1 - 2.9e-146 487.6 0.0 9.3e-146 485.9 0.0 1.8 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 PXF44632.1 - 9.5e-46 156.7 0.0 9.5e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF5076 PF16826.5 PXF44632.1 - 0.0038 17.1 0.1 7.2 6.6 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF5076) PRIMA1 PF16101.5 PXF44632.1 - 0.72 9.9 3.8 1.7 8.7 3.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 OTU PF02338.19 PXF44633.1 - 1.9e-16 60.7 0.0 3.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PXF44633.1 - 4.7e-06 26.2 0.0 0.031 13.7 0.0 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain GNAT_like PF18407.1 PXF44633.1 - 0.038 14.3 0.2 0.038 14.3 0.2 3.0 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain Methyltransf_31 PF13847.6 PXF44634.1 - 5.7e-20 71.7 0.0 9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF44634.1 - 1.2e-18 67.5 0.0 2.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF44634.1 - 1.3e-18 67.5 0.0 2.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF44634.1 - 2e-18 66.8 0.0 5.2e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF44634.1 - 2.2e-18 66.8 0.0 5.6e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF44634.1 - 8.1e-09 35.2 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PXF44634.1 - 4.7e-06 26.3 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 PXF44634.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PXF44634.1 - 6e-05 22.5 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 PXF44634.1 - 0.00015 20.9 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.18 PXF44634.1 - 0.0033 16.9 0.0 1.4 8.4 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 PXF44634.1 - 0.0049 17.9 0.1 0.015 16.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF44634.1 - 0.0089 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PXF44634.1 - 0.012 15.2 0.0 0.037 13.7 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 PXF44634.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain rRNA_methylase PF06962.12 PXF44634.1 - 0.045 13.7 0.0 0.76 9.8 0.0 2.2 1 1 0 1 1 1 0 Putative rRNA methylase TehB PF03848.14 PXF44634.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 PXF44634.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DUF1995 PF09353.10 PXF44635.1 - 5.1e-10 39.7 0.0 8.2e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) WD40 PF00400.32 PXF44636.1 - 5.6e-31 106.1 13.7 7.9e-06 26.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 PXF44636.1 - 3.8e-09 36.5 0.0 7.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Nup160 PF11715.8 PXF44636.1 - 4.5e-08 32.2 0.3 0.16 10.6 0.0 4.2 4 0 0 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PXF44636.1 - 4.9e-08 33.2 0.1 1.3 9.4 0.0 5.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF44636.1 - 0.0091 15.0 0.0 2.1 7.2 0.0 3.1 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PXF44636.1 - 1.3 9.6 5.9 22 5.7 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain DDE_Tnp_4 PF13359.6 PXF44638.1 - 4.6e-14 52.4 0.1 5.6e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_4 PF13701.6 PXF44638.1 - 0.091 11.0 0.1 0.12 10.6 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 PfkB PF00294.24 PXF44640.1 - 4.6e-26 91.8 0.0 7e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HSM3_C PF18794.1 PXF44640.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain SelR PF01641.18 PXF44641.1 - 1.6e-44 150.9 0.0 1.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 PXF44641.1 - 0.0033 17.6 0.0 0.0059 16.8 0.0 1.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 PXF44641.1 - 0.39 9.5 1.3 6 5.6 0.1 2.0 1 1 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Rubredoxin PF00301.20 PXF44642.1 - 9.6e-08 31.9 6.9 4.4e-06 26.6 6.9 2.2 1 1 0 1 1 1 1 Rubredoxin Zn_ribbon_SprT PF17283.2 PXF44642.1 - 0.00023 21.0 0.5 0.00054 19.8 0.5 1.7 1 1 0 1 1 1 1 SprT-like zinc ribbon domain Rubredoxin_2 PF18073.1 PXF44642.1 - 0.0037 17.0 2.6 0.87 9.4 0.5 2.4 2 0 0 2 2 2 2 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 PXF44642.1 - 0.0061 16.7 0.5 0.01 16.0 0.5 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-RRN7 PF11781.8 PXF44642.1 - 0.027 14.2 1.5 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PHD_4 PF16866.5 PXF44642.1 - 0.042 14.0 3.5 0.07 13.2 3.3 1.5 1 1 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 PXF44642.1 - 0.051 13.3 1.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 PXF44642.1 - 0.073 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 PXF44642.1 - 0.1 12.6 1.0 0.23 11.5 1.0 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid PHD PF00628.29 PXF44642.1 - 0.19 11.6 2.8 9 6.3 0.2 2.2 2 0 0 2 2 2 0 PHD-finger DUF4379 PF14311.6 PXF44642.1 - 0.8 10.1 6.7 13 6.2 0.8 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-RanBP PF00641.18 PXF44642.1 - 1.3 8.4 6.1 2.4 7.6 1.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Mito_carr PF00153.27 PXF44644.1 - 1.5e-61 204.3 7.3 1.3e-25 89.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ACOX PF01756.19 PXF44645.1 - 2.6e-14 53.2 0.1 4.9e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PXF44645.1 - 4.8e-12 45.9 0.0 8.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 PXF44645.1 - 2.1e-08 34.8 0.2 5.5e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 PXF44645.1 - 2e-07 31.4 1.4 6.7e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PXF44645.1 - 0.0005 20.7 0.1 0.0047 17.6 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Vta1 PF04652.16 PXF44645.1 - 0.012 15.6 0.3 0.021 14.8 0.3 1.3 1 0 0 1 1 1 0 Vta1 like Fimbrial_K88 PF02432.15 PXF44646.1 - 0.022 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Fimbrial, major and minor subunit PCIF1_WW PF12237.8 PXF44648.1 - 0.00026 20.6 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Pyr_redox_2 PF07992.14 PXF44650.1 - 1.2e-50 172.4 1.5 1.6e-50 172.1 1.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF44650.1 - 8.3e-12 45.5 0.2 1.1e-10 41.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF44650.1 - 1.1e-09 38.0 0.1 9.2e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PXF44650.1 - 0.00086 19.7 1.3 0.01 16.3 0.1 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 PXF44650.1 - 0.0095 15.1 0.0 0.0095 15.1 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 PXF44650.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PXF44650.1 - 0.11 12.6 0.7 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 PXF44650.1 - 0.67 9.2 4.0 2.7 7.3 0.5 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 PXF44650.1 - 7 6.1 8.8 3.5 7.1 0.1 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase Peptidase_S8 PF00082.22 PXF44651.1 - 7.3e-13 48.4 1.9 1e-12 48.0 1.9 1.2 1 0 0 1 1 1 1 Subtilase family NLBH PF05211.12 PXF44653.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.8 1 1 1 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) E1-E2_ATPase PF00122.20 PXF44654.1 - 2.2e-36 125.1 0.6 2.2e-36 125.1 0.6 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PXF44654.1 - 5.7e-34 117.4 1.3 5.7e-34 117.4 1.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 PXF44654.1 - 4.4e-19 68.3 0.0 9.1e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF44654.1 - 8.7e-18 65.4 0.2 2.8e-17 63.7 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PXF44654.1 - 8.6e-12 44.6 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PXF44654.1 - 1.4e-05 25.0 0.1 0.051 13.3 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3792 PF12670.7 PXF44654.1 - 0.0023 18.1 0.2 0.0023 18.1 0.2 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) HAD PF12710.7 PXF44654.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2417 PF10329.9 PXF44654.1 - 0.84 9.0 5.1 0.49 9.8 0.9 2.6 2 1 0 2 2 2 0 Region of unknown function (DUF2417) DUF3810 PF12725.7 PXF44654.1 - 1.9 7.8 7.2 9.8 5.4 0.9 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3810) C2 PF00168.30 PXF44655.1 - 0.0047 17.2 0.0 0.037 14.3 0.0 2.7 1 1 0 1 1 1 1 C2 domain SHMT PF00464.19 PXF44656.1 - 4.2e-184 611.8 0.0 4.8e-184 611.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 PXF44656.1 - 0.0015 17.9 0.0 0.02 14.1 0.0 2.5 1 1 0 1 1 1 1 Beta-eliminating lyase MPP6 PF10175.9 PXF44657.1 - 5.1e-10 40.0 0.0 7.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 LETM1 PF07766.13 PXF44657.1 - 0.0095 15.3 0.5 0.012 15.0 0.5 1.1 1 0 0 1 1 1 1 LETM1-like protein DSPc PF00782.20 PXF44658.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 PXF44658.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PXF44658.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2304 PF10066.9 PXF44659.1 - 1.2 9.4 7.7 25 5.1 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF3584 PF12128.8 PXF44660.1 - 0.00033 18.3 13.5 0.00043 18.0 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF812 PF05667.11 PXF44660.1 - 0.0004 19.4 12.1 0.00051 19.1 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FH2 PF02181.23 PXF44660.1 - 0.00055 19.2 8.0 0.013 14.7 1.1 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain TMF_DNA_bd PF12329.8 PXF44660.1 - 0.002 18.1 10.2 0.016 15.2 0.3 3.1 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Sec34 PF04136.15 PXF44660.1 - 0.0021 18.0 0.5 0.0021 18.0 0.5 2.4 2 1 0 2 2 2 1 Sec34-like family TACC_C PF05010.14 PXF44660.1 - 0.0036 17.1 0.5 0.0036 17.1 0.5 2.4 2 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Med28 PF11594.8 PXF44660.1 - 0.0038 17.3 0.6 0.0038 17.3 0.6 2.3 1 1 1 2 2 2 1 Mediator complex subunit 28 CALCOCO1 PF07888.11 PXF44660.1 - 0.0059 15.5 15.1 0.039 12.8 15.1 1.8 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like NB-LRR PF12061.8 PXF44660.1 - 0.0059 16.0 1.9 0.0059 16.0 1.9 2.5 1 1 2 3 3 3 1 Late blight resistance protein R1 Spc7 PF08317.11 PXF44660.1 - 0.0063 15.4 4.1 0.0063 15.4 4.1 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein Peptidase_C50 PF03568.17 PXF44660.1 - 0.007 15.5 7.6 0.009 15.2 7.6 1.1 1 0 0 1 1 1 1 Peptidase family C50 HBM PF16591.5 PXF44660.1 - 0.0072 15.8 14.8 0.034 13.6 10.8 2.1 1 1 1 2 2 2 1 Helical bimodular sensor domain Syntaxin-6_N PF09177.11 PXF44660.1 - 0.0091 16.5 8.4 0.029 14.9 2.3 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 PXF44660.1 - 0.0095 16.1 14.3 0.11 12.7 2.7 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding ABC_tran_Xtn PF12848.7 PXF44660.1 - 0.015 15.3 4.1 0.029 14.4 1.5 2.2 2 0 0 2 2 2 0 ABC transporter MEIOC PF15189.6 PXF44660.1 - 0.015 14.9 1.0 0.015 14.9 1.0 2.1 2 1 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC APG6_N PF17675.1 PXF44660.1 - 0.016 15.8 12.4 0.76 10.3 12.4 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region H-kinase_dim PF02895.14 PXF44660.1 - 0.018 15.4 0.9 0.018 15.4 0.9 3.0 1 1 2 3 3 2 0 Signal transducing histidine kinase, homodimeric domain ADIP PF11559.8 PXF44660.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 PXF44660.1 - 0.028 15.0 1.2 0.028 15.0 1.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA ApoO PF09769.9 PXF44660.1 - 0.041 13.8 8.7 2 8.4 0.8 3.5 1 1 1 2 2 2 0 Apolipoprotein O BLOC1_2 PF10046.9 PXF44660.1 - 0.047 14.0 0.3 0.047 14.0 0.3 3.0 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T2SSF PF00482.23 PXF44660.1 - 0.069 13.1 1.4 0.14 12.2 0.1 2.0 1 1 1 3 3 1 0 Type II secretion system (T2SS), protein F DUF4064 PF13273.6 PXF44660.1 - 0.076 13.3 0.1 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Pox_EPC_I2-L1 PF12575.8 PXF44660.1 - 0.083 13.1 3.3 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 PilJ PF13675.6 PXF44660.1 - 0.11 12.5 10.0 1.9 8.5 4.7 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term SLATT_6 PF18169.1 PXF44660.1 - 0.12 11.9 3.4 0.23 11.1 0.3 2.3 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 NPV_P10 PF05531.12 PXF44660.1 - 0.14 12.6 6.8 0.27 11.7 0.5 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 PXF44660.1 - 0.15 12.8 8.1 1.1 10.1 0.4 2.7 1 1 2 3 3 3 0 Occludin homology domain Fez1 PF06818.15 PXF44660.1 - 0.17 12.3 15.9 0.075 13.5 3.1 2.1 1 1 1 2 2 2 0 Fez1 Methyltransf_32 PF13679.6 PXF44660.1 - 0.2 11.7 6.0 0.15 12.0 4.5 1.6 1 1 0 1 1 1 0 Methyltransferase domain CheX PF13690.6 PXF44660.1 - 0.21 11.8 1.0 0.69 10.1 0.0 2.2 3 0 0 3 3 2 0 Chemotaxis phosphatase CheX AcetDehyd-dimer PF09290.11 PXF44660.1 - 0.22 11.7 1.5 2.2 8.5 0.1 2.3 1 1 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Fib_alpha PF08702.10 PXF44660.1 - 0.24 11.6 13.2 0.12 12.5 3.5 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 PXF44660.1 - 0.25 11.6 10.3 0.027 14.8 3.3 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein HemX PF04375.14 PXF44660.1 - 0.26 10.5 16.6 26 4.0 16.1 2.3 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FUSC PF04632.12 PXF44660.1 - 0.27 9.7 9.2 0.35 9.3 9.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Conotoxin PF02950.17 PXF44660.1 - 0.29 12.2 2.9 0.45 11.6 0.9 2.2 2 0 0 2 2 1 0 Conotoxin DUF924 PF06041.11 PXF44660.1 - 0.29 11.3 3.4 0.3 11.2 0.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) AAA_13 PF13166.6 PXF44660.1 - 0.3 9.7 12.9 0.4 9.3 12.9 1.1 1 0 0 1 1 1 0 AAA domain LPP PF04728.13 PXF44660.1 - 0.3 11.5 18.5 1.7 9.1 0.1 4.3 2 2 3 5 5 5 0 Lipoprotein leucine-zipper GAS PF13851.6 PXF44660.1 - 0.34 10.2 18.1 0.038 13.3 4.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 PXF44660.1 - 0.34 11.1 15.3 2.3 8.5 5.1 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PulG PF11773.8 PXF44660.1 - 0.41 10.5 5.7 0.13 12.1 2.0 2.0 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Laminin_II PF06009.12 PXF44660.1 - 0.41 10.7 17.6 1 9.3 5.5 2.6 1 1 1 2 2 2 0 Laminin Domain II Tup_N PF08581.10 PXF44660.1 - 0.43 10.9 7.8 0.57 10.5 0.2 2.9 2 1 0 2 2 2 0 Tup N-terminal CREPT PF16566.5 PXF44660.1 - 0.51 10.5 13.7 0.11 12.7 3.7 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2730 PF10805.8 PXF44660.1 - 0.54 10.4 6.8 2.2 8.4 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) PIN_8 PF18476.1 PXF44660.1 - 0.55 10.1 12.4 0.56 10.0 6.1 2.0 1 1 1 2 2 2 0 PIN like domain Alpha_Helical PF18489.1 PXF44660.1 - 0.74 10.0 4.1 1.7 8.9 0.2 2.4 1 1 0 2 2 2 0 Alpha helical domain DUF1664 PF07889.12 PXF44660.1 - 0.77 9.8 21.5 0.29 11.2 5.6 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF3365 PF11845.8 PXF44660.1 - 0.82 10.0 3.7 2.4 8.5 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) RskA PF10099.9 PXF44660.1 - 0.84 9.9 3.9 1.1 9.5 0.9 2.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Atg14 PF10186.9 PXF44660.1 - 0.93 8.5 10.5 2.7 7.0 10.5 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 PXF44660.1 - 0.97 9.8 18.8 1.1 9.7 5.8 2.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CLZ PF16526.5 PXF44660.1 - 1.1 9.6 9.5 1.9 8.9 0.2 3.2 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA1 PF07160.12 PXF44660.1 - 1.3 8.8 14.7 0.44 10.3 1.3 2.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 L31 PF09784.9 PXF44660.1 - 1.5 9.3 7.1 1.2 9.6 0.3 2.3 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 RSS_P20 PF11757.8 PXF44660.1 - 1.5 9.3 4.8 15 6.1 3.8 2.4 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain ZapB PF06005.12 PXF44660.1 - 1.7 9.1 10.8 0.63 10.5 0.8 3.2 2 1 1 3 3 3 0 Cell division protein ZapB FliD_N PF02465.18 PXF44660.1 - 2.1 9.1 14.0 1.8 9.3 1.1 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spc29 PF17082.5 PXF44660.1 - 2.1 8.1 8.9 0.15 11.9 1.5 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF2570 PF10828.8 PXF44660.1 - 2.4 8.0 16.6 0.69 9.8 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) WXG100 PF06013.12 PXF44660.1 - 2.8 8.2 10.5 9.4 6.5 0.1 3.2 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DivIC PF04977.15 PXF44660.1 - 3.6 7.4 13.3 2 8.2 0.3 3.1 2 1 1 3 3 3 0 Septum formation initiator kleA_kleC PF17383.2 PXF44660.1 - 3.6 8.0 7.6 3.6 8.0 0.2 3.0 2 1 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF724 PF05266.14 PXF44660.1 - 4.1 7.2 15.0 1.5 8.6 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 PXF44660.1 - 4.7 6.5 12.6 6 6.1 12.6 1.1 1 0 0 1 1 1 0 FAM76 protein DUF2408 PF10303.9 PXF44660.1 - 5.2 7.6 13.3 5.4 7.6 8.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) USP8_interact PF08941.10 PXF44660.1 - 5.9 6.7 9.9 2.8 7.7 0.6 2.2 1 1 1 2 2 2 0 USP8 interacting TPR_MLP1_2 PF07926.12 PXF44660.1 - 5.9 7.0 19.4 9.4 6.3 5.1 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PXF44660.1 - 6.6 6.0 18.6 0.13 11.5 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 PXF44660.1 - 7.3 6.9 16.4 1.6 9.1 0.6 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4559 PF15112.6 PXF44660.1 - 8.4 6.0 13.1 4.8 6.8 10.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) FAD-SLDH PF12318.8 PXF44660.1 - 9.3 6.3 9.9 6.4 6.8 0.9 2.3 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase ThylakoidFormat PF11264.8 PXF44661.1 - 1.5e-39 135.9 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein DUF2244 PF10003.9 PXF44661.1 - 0.18 11.5 1.0 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) N2227 PF07942.12 PXF44663.1 - 2e-53 181.4 0.0 2.7e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_25 PF13649.6 PXF44663.1 - 0.006 17.3 0.0 0.41 11.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF44663.1 - 0.012 16.2 0.0 0.063 13.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain MARCKS PF02063.17 PXF44663.1 - 0.054 13.5 0.6 0.075 13.0 0.6 1.1 1 0 0 1 1 1 0 MARCKS family Methyltransf_23 PF13489.6 PXF44663.1 - 0.094 12.6 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_8 PF05148.15 PXF44663.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_12 PF08242.12 PXF44663.1 - 0.17 12.6 0.0 0.68 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain SHOCT PF09851.9 PXF44664.1 - 0.0041 16.8 0.8 0.98 9.2 0.1 2.5 2 0 0 2 2 2 2 Short C-terminal domain DUF2614 PF11023.8 PXF44664.1 - 0.053 13.6 0.1 0.14 12.3 0.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon containing domain zf-C4_Topoisom PF01396.19 PXF44664.1 - 0.086 12.6 3.1 6.7 6.6 0.3 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger TerY_C PF15616.6 PXF44664.1 - 0.13 12.4 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-CCHC_5 PF14787.6 PXF44664.1 - 4 7.2 6.7 0.25 11.1 0.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C3HC4_2 PF13923.6 PXF44666.1 - 0.0002 21.1 4.7 0.0002 21.1 4.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF44666.1 - 0.00037 20.8 5.7 0.00037 20.8 5.7 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PXF44666.1 - 0.0025 17.7 5.9 0.0025 17.7 5.9 2.8 3 1 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 PXF44666.1 - 0.0043 17.3 4.6 0.0043 17.3 4.6 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-B_box PF00643.24 PXF44666.1 - 0.02 15.1 3.6 0.02 15.1 3.6 3.4 5 0 0 5 5 5 0 B-box zinc finger NADHdh_A3 PF14987.6 PXF44667.1 - 4.8e-05 23.6 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 DASH_Dad1 PF08649.10 PXF44668.1 - 0.018 15.2 1.0 0.031 14.4 1.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 UPF0047 PF01894.17 PXF44669.1 - 1.8e-33 115.1 0.0 2.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RNA_pol_I_A49 PF06870.12 PXF44670.1 - 1e-47 162.9 0.2 1.3e-47 162.5 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor ApoLp-III PF07464.11 PXF44670.1 - 0.16 12.1 0.4 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SF3b10 PF07189.11 PXF44671.1 - 4.3e-30 103.6 0.0 5.7e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Tweety PF04906.13 PXF44672.1 - 4.1e-07 29.0 4.5 9.5e-05 21.2 1.1 2.8 1 1 1 2 2 2 2 Tweety SUR7 PF06687.12 PXF44672.1 - 5.4 6.6 21.6 1.1 8.8 1.7 2.9 2 1 0 3 3 3 0 SUR7/PalI family DUF1690 PF07956.11 PXF44673.1 - 1.9e-08 34.8 3.0 5.9e-08 33.2 3.0 1.7 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 PXF44673.1 - 0.0055 16.8 0.4 0.01 16.0 0.4 1.5 1 0 0 1 1 1 1 CHCH domain RRM_1 PF00076.22 PXF44674.1 - 6.5e-15 54.7 0.0 8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF44674.1 - 0.00024 20.7 0.0 0.00029 20.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Formyl_trans_N PF00551.19 PXF44675.1 - 1.2e-41 142.5 0.0 1.5e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Vitellogenin_N PF01347.22 PXF44675.1 - 0.25 9.7 0.0 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region MutS_V PF00488.21 PXF44676.1 - 7.1e-34 117.5 0.0 6.3e-31 107.9 0.0 2.8 3 0 0 3 3 3 2 MutS domain V MutS_III PF05192.18 PXF44676.1 - 8.7e-22 78.3 0.1 1.5e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 PXF44676.1 - 0.07 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV PikAIV_N PF18605.1 PXF44676.1 - 0.14 11.7 2.4 5.6 6.6 0.2 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DDT PF02791.17 PXF44678.1 - 7e-11 42.3 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 PXF44678.1 - 6.3e-06 26.6 2.9 6.3e-06 26.6 2.9 2.8 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MHB PF16525.5 PXF44678.1 - 0.48 10.7 4.4 0.13 12.5 0.3 2.2 2 0 0 2 2 2 0 Haemophore, haem-binding Ank_5 PF13857.6 PXF44679.1 - 5.6e-10 39.3 0.0 3.3e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PXF44679.1 - 3e-08 34.1 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PXF44679.1 - 8.1e-07 28.9 0.0 0.15 12.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PXF44679.1 - 1.7e-06 28.5 0.0 1.3e-05 25.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PXF44679.1 - 0.00016 21.9 0.8 0.84 10.2 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Pro_isomerase PF00160.21 PXF44680.1 - 1.6e-34 119.4 0.0 2.4e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PXF44680.1 - 5.8e-12 45.2 0.0 1.5e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDP_Man_Dehyd PF16363.5 PXF44681.1 - 3.2e-52 178.0 0.0 9.4e-52 176.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF44681.1 - 5.2e-47 160.3 0.0 6.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF44681.1 - 9.1e-11 41.3 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PXF44681.1 - 1.7e-08 34.0 0.0 0.0012 18.1 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 PXF44681.1 - 1.3e-06 27.8 0.0 0.00031 20.0 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 PXF44681.1 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 PXF44681.1 - 0.0056 15.8 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 PXF44681.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Glyoxalase PF00903.25 PXF44683.1 - 3e-16 59.8 0.3 1.2e-13 51.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF44683.1 - 3.2e-13 49.9 0.0 3.5e-06 27.3 0.0 2.9 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PXF44683.1 - 2.8e-07 30.8 0.0 0.0016 18.6 0.0 3.3 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 PXF44683.1 - 3.3e-05 24.1 0.1 0.00015 21.9 0.1 2.0 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal GntR PF00392.21 PXF44683.1 - 0.0075 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Pirin_C PF05726.13 PXF44684.1 - 3.9e-13 49.6 0.0 6.5e-05 23.2 0.0 2.8 3 0 0 3 3 3 2 Pirin C-terminal cupin domain Pirin PF02678.16 PXF44684.1 - 6.1e-12 45.5 0.0 1.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Pirin Aldo_ket_red PF00248.21 PXF44685.1 - 1.1e-54 185.6 0.0 1.4e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 PXF44686.1 - 7.8e-18 64.0 34.1 3.5e-05 24.0 0.3 6.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PXF44686.1 - 3.1e-17 62.0 29.2 0.001 19.4 1.6 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF44686.1 - 2.8e-14 52.6 29.5 0.0041 17.9 0.2 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.12 PXF44686.1 - 0.00095 19.4 14.8 0.0086 16.3 0.4 3.4 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 PXF44686.1 - 0.0015 18.8 10.0 0.046 14.0 1.5 2.8 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PXF44686.1 - 0.0017 18.3 19.2 0.4 10.8 1.6 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 PXF44686.1 - 0.0018 18.9 4.4 0.28 11.9 1.2 3.5 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 PXF44686.1 - 0.0038 17.5 18.1 9.1 6.7 1.3 6.0 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.22 PXF44686.1 - 0.017 15.0 6.9 0.62 10.0 1.1 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 PXF44686.1 - 0.019 14.8 0.3 0.019 14.8 0.3 5.1 5 1 0 5 5 5 0 zinc-finger C2H2-type Rad50_zn_hook PF04423.14 PXF44686.1 - 0.074 12.9 2.7 3.2 7.7 0.1 2.7 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-met PF12874.7 PXF44686.1 - 0.13 12.7 13.9 18 5.9 0.0 5.8 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Sina PF03145.16 PXF44686.1 - 0.25 11.3 12.6 0.67 9.9 4.3 2.8 1 1 2 3 3 3 0 Seven in absentia protein family GAGA PF09237.11 PXF44686.1 - 0.37 10.6 13.0 7.8 6.4 0.1 4.2 1 1 3 4 4 4 0 GAGA factor DUF4764 PF15961.5 PXF44686.1 - 1.3 7.6 9.7 1.4 7.5 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) C1_4 PF07975.12 PXF44686.1 - 1.3 9.3 8.8 2.8 8.3 1.2 2.7 1 1 0 2 2 2 0 TFIIH C1-like domain zf-CRD PF17979.1 PXF44686.1 - 1.4 9.0 8.9 1.4 9.0 3.8 2.4 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE PF01363.21 PXF44686.1 - 1.9 8.6 17.3 93 3.3 12.3 4.0 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HE PF16278.5 PXF44686.1 - 2.4 8.7 14.6 5e+02 1.3 0.0 4.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 PXF44686.1 - 2.7 8.1 6.5 6.4 6.9 0.1 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf_ZIC PF18366.1 PXF44686.1 - 3.2 7.9 8.3 3.9 7.7 0.8 3.5 1 1 2 3 3 3 0 Zic proteins zinc finger domain TRAF6_Z2 PF18048.1 PXF44686.1 - 3.4 7.8 7.7 9.5 6.4 0.0 3.2 4 0 0 4 4 3 0 TNF receptor-associated factor 6 zinc finger 2 NADH-G_4Fe-4S_3 PF10588.9 PXF44686.1 - 6.1 6.5 8.8 13 5.5 0.6 3.5 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2HC_2 PF13913.6 PXF44686.1 - 7.3 6.6 16.7 1.2 9.2 1.1 4.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Mg-por_mtran_C PF07109.11 PXF44687.1 - 4.5e-35 119.9 0.0 8.7e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 PXF44687.1 - 1e-12 48.6 0.1 2.2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF44687.1 - 7.6e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF44687.1 - 1.7e-09 37.6 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF44687.1 - 7e-09 36.3 0.0 1.5e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF44687.1 - 1.3e-07 31.8 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF44687.1 - 4.2e-07 30.5 0.1 1.3e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PXF44687.1 - 0.00031 20.3 0.1 0.00047 19.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PXF44687.1 - 0.001 18.6 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PXF44687.1 - 0.0066 16.4 0.0 0.088 12.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Zn_ribbon_17 PF17120.5 PXF44687.1 - 0.023 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TehB PF03848.14 PXF44687.1 - 0.035 13.5 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF4520 PF15016.6 PXF44687.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) SAGA-Tad1 PF12767.7 PXF44688.1 - 9e-18 64.9 0.1 5.8e-17 62.2 0.1 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit CMAS PF02353.20 PXF44689.1 - 2.9e-72 243.3 0.0 8.9e-72 241.7 0.0 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 PXF44689.1 - 1.3e-12 48.2 0.0 4.4e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF44689.1 - 1.5e-10 41.5 0.1 5.2e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF44689.1 - 2e-09 37.5 0.0 5.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF44689.1 - 6.8e-09 35.7 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF44689.1 - 3.7e-07 30.8 0.0 1.4e-06 28.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain SLIDE PF09111.10 PXF44689.1 - 0.00017 21.6 2.6 1.5 8.8 0.0 4.4 4 0 0 4 4 4 1 SLIDE FYRN PF05964.14 PXF44689.1 - 0.00039 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 PXF44689.1 - 0.00052 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus MTS PF05175.14 PXF44689.1 - 0.0048 16.5 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PXF44689.1 - 0.027 13.8 0.0 0.065 12.6 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.17 PXF44689.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 PXF44689.1 - 1.7 8.6 4.4 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 PXF44689.1 - 4.3 6.2 5.2 22 3.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1698) NOA36 PF06524.12 PXF44689.1 - 5 6.3 8.3 1.9 7.8 4.9 2.0 2 0 0 2 2 2 0 NOA36 protein Myb_DNA-binding PF00249.31 PXF44690.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF44690.1 - 0.015 15.5 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3439 PF11921.8 PXF44690.1 - 0.041 13.9 3.1 0.11 12.5 3.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TFIIA PF03153.13 PXF44690.1 - 0.22 11.5 7.9 0.23 11.4 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 PXF44690.1 - 0.86 10.0 4.0 1.6 9.1 3.6 1.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex KCNQ2_u3 PF16642.5 PXF44690.1 - 4.4 8.4 9.0 4.7 8.3 5.2 2.5 1 1 2 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PRKG1_interact PF15898.5 PXF44690.1 - 4.6 8.2 8.9 2.4 9.1 5.4 2.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Myb_DNA-binding PF00249.31 PXF44691.1 - 2.8e-10 40.2 0.0 7.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nucleotid_trans PF03407.16 PXF44692.1 - 1.5e-13 51.2 0.0 3.4e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF296 PF03479.15 PXF44692.1 - 0.11 12.9 0.0 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain zf-C2H2_jaz PF12171.8 PXF44693.1 - 5e-11 42.6 1.1 5e-11 42.6 1.1 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF44693.1 - 0.0077 16.6 0.3 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type NTP_transferase PF00483.23 PXF44694.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Exo_endo_phos PF03372.23 PXF44695.1 - 6.1e-13 48.8 0.0 1.4e-11 44.3 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PXF44695.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Peptidase_C48 PF02902.19 PXF44696.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Epimerase PF01370.21 PXF44697.1 - 1.4e-28 100.0 0.0 1.8e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF44697.1 - 5.2e-27 94.6 0.0 7.2e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PXF44697.1 - 3.2e-26 92.5 0.0 7e-26 91.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PXF44697.1 - 8.1e-22 77.6 0.0 5.2e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PXF44697.1 - 3.6e-18 65.7 0.0 1.2e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PXF44697.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PXF44697.1 - 8.5e-10 38.2 0.0 1.2e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 PXF44697.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 PXF44697.1 - 0.017 14.7 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Ldh_1_N PF00056.23 PXF44697.1 - 0.13 12.3 0.1 0.47 10.5 0.1 1.9 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain UQ_con PF00179.26 PXF44698.1 - 1.5e-11 44.1 0.0 6.5e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 PXF44698.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain Ribosomal_L34e PF01199.18 PXF44699.1 - 9.3e-34 115.6 0.9 9.3e-34 115.6 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e TSA PF03249.13 PXF44699.1 - 0.011 14.6 0.2 0.013 14.3 0.2 1.0 1 0 0 1 1 1 0 Type specific antigen MscS_TM PF12794.7 PXF44699.1 - 0.11 11.3 0.7 0.14 11.0 0.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Mito_carr PF00153.27 PXF44700.1 - 2.3e-26 91.6 0.3 7.8e-12 45.0 0.0 3.2 2 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF44700.1 - 0.011 14.9 0.0 0.15 11.2 0.0 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease bZIP_1 PF00170.21 PXF44701.1 - 0.0061 16.6 6.4 0.011 15.8 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Efg1 PF10153.9 PXF44701.1 - 0.038 14.4 4.2 0.057 13.8 4.2 1.3 1 0 0 1 1 1 0 rRNA-processing protein Efg1 SRP54 PF00448.22 PXF44704.1 - 3.1e-67 226.0 0.1 5e-67 225.3 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 PXF44704.1 - 1.2e-09 38.3 1.8 1.2e-09 38.3 1.8 2.3 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_31 PF13614.6 PXF44704.1 - 5.3e-07 29.7 1.0 0.008 16.1 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 PXF44704.1 - 1.9e-05 25.1 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.23 PXF44704.1 - 4.1e-05 23.6 0.3 0.00013 22.0 0.1 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 PXF44704.1 - 0.00017 21.9 0.0 0.00048 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PXF44704.1 - 0.00022 20.6 0.1 0.00062 19.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 PXF44704.1 - 0.00026 20.8 1.1 0.00049 19.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF44704.1 - 0.00029 20.6 1.5 0.00062 19.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PXF44704.1 - 0.00031 21.1 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 PXF44704.1 - 0.0009 19.1 0.1 0.0045 16.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArsA_ATPase PF02374.15 PXF44704.1 - 0.0012 18.1 0.3 0.23 10.6 0.0 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase MeaB PF03308.16 PXF44704.1 - 0.0014 17.7 0.7 0.023 13.7 0.1 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 PXF44704.1 - 0.0015 18.5 0.1 0.0061 16.6 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 PXF44704.1 - 0.0017 17.3 0.5 0.0043 16.0 0.5 1.6 1 1 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 PXF44704.1 - 0.0033 17.4 0.1 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Fer4_NifH PF00142.18 PXF44704.1 - 0.0037 16.8 0.4 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.27 PXF44704.1 - 0.0068 16.9 0.0 0.016 15.7 0.0 1.8 2 0 0 2 2 1 1 ABC transporter NTP_transf_3 PF12804.7 PXF44704.1 - 0.0071 16.7 0.1 0.019 15.3 0.0 1.8 2 0 0 2 2 1 1 MobA-like NTP transferase domain AAA_28 PF13521.6 PXF44704.1 - 0.0092 16.2 0.1 0.027 14.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 PXF44704.1 - 0.012 15.5 0.3 0.047 13.5 0.1 2.1 2 0 0 2 2 2 0 Helicase NACHT PF05729.12 PXF44704.1 - 0.027 14.4 0.1 0.079 12.9 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 PXF44704.1 - 0.029 14.4 0.0 0.064 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 PXF44704.1 - 0.041 13.5 0.1 3.7 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PXF44704.1 - 0.042 14.0 0.2 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PXF44704.1 - 0.051 13.3 0.5 0.17 11.7 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PXF44704.1 - 0.052 14.0 0.8 0.3 11.5 0.0 2.5 2 2 1 3 3 3 0 AAA domain AAA_15 PF13175.6 PXF44704.1 - 0.062 13.0 0.2 9.6 5.8 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.29 PXF44704.1 - 0.099 13.1 0.0 0.32 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 PXF44704.1 - 0.1 12.1 0.1 0.39 10.2 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 PXF44704.1 - 1.1 9.7 3.8 9.9 6.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Hemerythrin PF01814.23 PXF44705.1 - 0.0018 18.9 0.0 0.051 14.2 0.0 2.1 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain YGGT PF02325.17 PXF44706.1 - 1.3e-14 54.3 3.2 1.9e-14 53.8 3.2 1.2 1 0 0 1 1 1 1 YGGT family AAA PF00004.29 PXF44707.1 - 1.8e-24 86.6 0.0 3.5e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PXF44707.1 - 2.1e-10 40.4 0.8 3.7e-10 39.6 0.2 1.7 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PXF44707.1 - 1.7e-08 34.2 0.2 3.1e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 PXF44707.1 - 0.016 15.3 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Prot_ATP_OB_N PF17758.1 PXF44707.1 - 0.088 12.5 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Cullin PF00888.22 PXF44708.1 - 1e-161 539.7 4.1 1e-161 539.7 4.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 PXF44708.1 - 8.5e-24 83.4 3.0 1.5e-23 82.6 0.8 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Stork_head PF10264.9 PXF44708.1 - 0.0066 16.6 0.6 2.6 8.3 0.1 2.7 2 0 0 2 2 2 2 Winged helix Storkhead-box1 domain DUF4460 PF14687.6 PXF44709.1 - 2.4e-11 43.7 0.0 5.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 PXF44709.1 - 9.2e-08 32.2 0.0 2.3e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4461) FAD_binding_4 PF01565.23 PXF44710.1 - 2.5e-25 88.8 0.3 4.5e-25 88.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 PXF44710.1 - 1.2e-18 67.9 2.0 2.7e-18 66.7 2.0 1.6 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Tfb2 PF03849.14 PXF44711.1 - 5.8e-87 292.0 0.0 7.6e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PXF44711.1 - 8.7e-20 70.9 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PXF44711.1 - 0.0017 18.5 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sensor PF13796.6 PXF44712.1 - 0.12 12.4 0.6 0.23 11.5 0.6 1.4 1 0 0 1 1 1 0 Putative sensor AAA PF00004.29 PXF44713.1 - 2.7e-96 319.1 0.0 1.1e-47 161.7 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF44713.1 - 2.3e-25 88.1 9.3 2.9e-13 49.4 0.3 3.2 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 PXF44713.1 - 3.8e-21 75.1 0.5 1e-20 73.7 0.5 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 PXF44713.1 - 9.9e-14 51.4 0.0 2.1e-05 24.4 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PXF44713.1 - 2.8e-12 47.1 0.0 8.5e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PXF44713.1 - 4.3e-12 46.7 1.9 0.00038 20.9 0.1 4.2 3 2 1 4 4 3 2 AAA ATPase domain CDC48_2 PF02933.17 PXF44713.1 - 2.5e-11 43.2 0.0 5.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 PXF44713.1 - 3.1e-11 43.6 0.0 3.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PXF44713.1 - 9.1e-11 41.9 0.1 1.3e-05 25.2 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF44713.1 - 9.7e-09 35.6 0.2 0.063 13.6 0.0 4.0 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 PXF44713.1 - 1.2e-08 34.6 0.0 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 PXF44713.1 - 2.3e-07 30.9 0.0 0.0088 16.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 PXF44713.1 - 2.7e-07 30.2 0.3 0.03 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PXF44713.1 - 5.6e-07 29.9 0.0 0.028 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 PXF44713.1 - 6e-07 29.6 0.1 0.61 10.0 0.0 3.7 3 1 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 PXF44713.1 - 1e-06 29.3 0.0 0.027 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PXF44713.1 - 6.7e-06 25.9 0.0 0.077 12.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 PXF44713.1 - 7.2e-06 25.9 0.6 9e-05 22.4 0.2 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 PXF44713.1 - 9.6e-06 25.6 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 PXF44713.1 - 1.6e-05 24.8 0.0 0.0096 15.7 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 PXF44713.1 - 2e-05 25.1 0.1 0.42 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 PXF44713.1 - 2.2e-05 25.0 0.0 0.061 13.8 0.0 2.7 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.17 PXF44713.1 - 3.3e-05 23.1 0.1 0.073 12.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 PXF44713.1 - 4.7e-05 23.1 3.4 0.96 9.0 0.1 4.1 3 2 1 5 5 4 1 AAA domain ATPase PF06745.13 PXF44713.1 - 4.7e-05 22.8 0.9 3.5 6.9 0.0 3.9 4 0 0 4 4 4 0 KaiC NACHT PF05729.12 PXF44713.1 - 4.7e-05 23.4 0.1 0.36 10.7 0.0 3.6 3 1 0 4 4 4 1 NACHT domain AAA_7 PF12775.7 PXF44713.1 - 4.8e-05 23.0 0.0 0.14 11.6 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 PXF44713.1 - 4.9e-05 23.1 0.0 0.36 10.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 PXF44713.1 - 5.8e-05 22.4 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 PXF44713.1 - 6.2e-05 23.3 0.1 0.73 10.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 PXF44713.1 - 0.00014 21.6 0.1 1 9.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 PXF44713.1 - 0.00015 21.7 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 PXF44713.1 - 0.00028 20.2 0.0 0.47 9.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 PXF44713.1 - 0.0011 19.1 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 PXF44713.1 - 0.0012 18.0 0.0 0.49 9.5 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.9 PXF44713.1 - 0.0015 17.8 0.0 0.92 8.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 PXF44713.1 - 0.0017 18.2 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PXF44713.1 - 0.0018 17.8 0.2 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 PXF44713.1 - 0.0026 17.8 0.0 0.81 9.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 PXF44713.1 - 0.0046 16.8 0.6 7.4 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PXF44713.1 - 0.0075 16.6 0.4 6.7 7.0 0.0 3.5 3 1 0 4 4 4 0 AAA domain SKI PF01202.22 PXF44713.1 - 0.012 15.7 0.4 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase Rad17 PF03215.15 PXF44713.1 - 0.013 15.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 PXF44713.1 - 0.014 15.4 0.6 3.9 7.4 0.0 3.9 3 1 0 4 4 4 0 NTPase Cytidylate_kin2 PF13189.6 PXF44713.1 - 0.016 15.4 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family UFD1 PF03152.14 PXF44713.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 PXF44713.1 - 0.022 14.4 0.0 2.6 7.7 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 PXF44713.1 - 0.034 13.9 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 PXF44713.1 - 0.044 13.5 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_23 PF13476.6 PXF44713.1 - 0.077 13.5 0.7 17 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 PXF44713.1 - 0.13 12.6 2.6 31 4.8 0.0 3.8 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain PGK PF00162.19 PXF44713.1 - 0.13 11.2 0.2 6.2 5.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoglycerate kinase KAP_NTPase PF07693.14 PXF44713.1 - 0.13 11.5 0.0 8.5 5.5 0.0 2.7 2 2 1 3 3 3 0 KAP family P-loop domain AAA_29 PF13555.6 PXF44713.1 - 0.16 11.7 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.16 PXF44713.1 - 0.34 9.7 5.9 12 4.7 0.0 3.5 4 0 0 4 4 4 0 AFG1-like ATPase Nas2_N PF18265.1 PXF44714.1 - 2.9e-23 81.6 0.0 4.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 PXF44714.1 - 3.3e-05 23.6 0.0 0.00016 21.5 0.0 2.0 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 PXF44714.1 - 0.00086 19.6 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 PXF44714.1 - 0.0041 17.4 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain UcrQ PF02939.16 PXF44715.1 - 6.2e-11 42.1 0.0 7.4e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L12 PF00542.19 PXF44716.1 - 1.3e-23 83.1 6.1 1.3e-23 83.1 6.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 PXF44716.1 - 4.2e-09 36.0 9.5 1.3e-08 34.4 6.9 2.7 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain WD40 PF00400.32 PXF44717.1 - 1.8e-32 110.8 19.9 1e-06 29.3 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 PXF44717.1 - 1.9e-05 23.5 2.8 0.15 10.6 0.1 3.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PXF44717.1 - 0.0044 17.3 0.0 15 6.0 0.0 4.2 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Spc24 PF08286.11 PXF44717.1 - 0.077 13.2 2.0 0.15 12.3 2.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 EzrA PF06160.12 PXF44717.1 - 0.079 11.1 0.8 0.11 10.7 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 PXF44717.1 - 0.08 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WD40_like PF17005.5 PXF44717.1 - 0.14 11.5 0.0 5.6 6.2 0.0 1.9 1 1 1 2 2 2 0 WD40-like domain Formyl_trans_C PF02911.18 PXF44717.1 - 0.2 11.9 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Pkinase PF00069.25 PXF44718.1 - 1.2e-49 169.1 0.1 1.7e-49 168.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44718.1 - 7.8e-34 117.1 0.1 1.3e-33 116.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PXF44718.1 - 9.1e-31 106.3 0.0 3.1e-09 37.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF44718.1 - 7.2e-25 86.7 0.3 3.7e-07 30.3 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PXF44718.1 - 2.3e-22 79.0 0.6 5.8e-08 33.1 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PXF44718.1 - 8.2e-21 73.5 4.9 3.3e-07 30.5 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 PXF44718.1 - 1.5e-18 64.9 1.4 9.7e-05 22.5 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat OSR1_C PF12202.8 PXF44718.1 - 0.052 13.8 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain ER_lumen_recept PF00810.18 PXF44719.1 - 4.8e-56 189.7 11.7 7.5e-56 189.0 11.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor COX7B PF05392.11 PXF44719.1 - 0.0057 16.3 0.1 0.0057 16.3 0.1 1.9 2 0 0 2 2 2 1 Cytochrome C oxidase chain VIIB PQ-loop PF04193.14 PXF44719.1 - 0.034 13.9 13.0 0.78 9.6 0.5 4.0 4 1 1 5 5 5 0 PQ loop repeat AraC_binding PF02311.19 PXF44719.1 - 0.5 10.3 3.4 0.94 9.4 0.1 2.5 3 0 0 3 3 3 0 AraC-like ligand binding domain Glyco_transf_8 PF01501.20 PXF44720.1 - 0.037 13.6 0.3 0.1 12.2 0.3 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 Sel1 PF08238.12 PXF44721.1 - 1.3e-24 86.1 33.2 7.9e-06 26.4 0.2 11.0 11 0 0 11 11 11 7 Sel1 repeat Phage_holin_3_6 PF07332.11 PXF44721.1 - 0.013 15.6 3.0 0.89 9.6 0.1 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_3 PF07720.12 PXF44721.1 - 0.55 10.3 6.9 0.16 12.0 1.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.15 PXF44722.1 - 3e-108 362.9 29.9 3.5e-108 362.7 29.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PP2C PF00481.21 PXF44723.1 - 6.6e-41 140.6 0.0 8.1e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF44723.1 - 8.4e-08 32.1 0.0 1.6e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C GDPD PF03009.17 PXF44724.1 - 1e-28 100.8 0.0 1.3e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Cnd1 PF12717.7 PXF44725.1 - 3.6e-08 33.6 0.2 1.5e-07 31.6 0.0 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PXF44725.1 - 7.8e-07 29.4 10.3 0.0001 22.6 2.1 4.6 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 PXF44725.1 - 6.8e-06 25.9 7.0 0.41 11.0 0.1 5.1 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.20 PXF44725.1 - 0.00018 20.2 0.1 0.025 13.1 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region SIL1 PF16782.5 PXF44725.1 - 0.00051 19.4 0.6 0.002 17.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor SIL1 V-ATPase_H_C PF11698.8 PXF44725.1 - 0.0023 18.1 2.6 1.7 8.8 0.1 3.8 2 1 2 4 4 4 3 V-ATPase subunit H Arm PF00514.23 PXF44725.1 - 0.0062 16.5 0.9 1.8 8.7 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PXF44725.1 - 0.0069 16.9 10.4 0.82 10.2 0.2 5.0 5 2 0 5 5 5 1 HEAT-like repeat Fes1 PF08609.10 PXF44725.1 - 0.015 16.1 0.4 0.015 16.1 0.4 2.5 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 Iso_dh PF00180.20 PXF44726.1 - 2.1e-73 247.5 0.1 2.5e-73 247.2 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COG5 PF10392.9 PXF44727.1 - 1.5e-08 34.9 1.3 2.7e-08 34.0 1.3 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 LPP PF04728.13 PXF44727.1 - 0.021 15.2 0.0 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper TPR_6 PF13174.6 PXF44727.1 - 0.1 13.3 0.1 8.7 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat POTRA_TamA_1 PF17243.2 PXF44727.1 - 0.12 12.5 0.1 0.49 10.5 0.1 2.0 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Peptidase_M50 PF02163.22 PXF44729.1 - 2.4e-11 43.4 4.3 1e-09 38.0 4.3 2.4 1 1 0 1 1 1 1 Peptidase family M50 BTB PF00651.31 PXF44731.1 - 3.9e-14 52.8 0.7 1.2e-13 51.3 0.7 1.9 1 1 0 1 1 1 1 BTB/POZ domain Citrate_bind PF16114.5 PXF44732.1 - 1.8e-72 242.6 0.0 2.5e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 PXF44732.1 - 1.5e-11 44.3 0.0 3e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain DUF5119 PF17145.4 PXF44732.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) EnY2 PF10163.9 PXF44733.1 - 9.1e-15 54.8 0.1 1.5e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 AbiTii PF18864.1 PXF44733.1 - 0.028 14.6 0.0 0.031 14.4 0.0 1.2 1 1 0 1 1 1 0 AbiTii DUF1476 PF07345.11 PXF44733.1 - 0.094 13.1 0.6 15 6.0 0.0 2.2 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DSPc PF00782.20 PXF44735.1 - 2.3e-26 92.2 0.1 3.2e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PXF44735.1 - 0.0025 17.4 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Phage_sheath_1 PF04984.14 PXF44735.1 - 0.041 13.8 0.1 0.087 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain MEDS PF14417.6 PXF44735.1 - 0.093 12.6 0.5 0.16 11.8 0.5 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA PF00004.29 PXF44736.1 - 2.2e-42 144.6 0.0 4e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PXF44736.1 - 2.5e-22 78.6 0.0 6.7e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 PXF44736.1 - 1.9e-08 34.2 5.4 5.9e-08 32.7 5.4 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 PXF44736.1 - 1.7e-07 31.0 0.0 5.6e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 PXF44736.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PXF44736.1 - 2.4e-05 24.8 0.2 0.00017 22.0 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 PXF44736.1 - 3.3e-05 23.7 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 PXF44736.1 - 5.2e-05 23.5 1.0 0.0049 17.2 0.2 2.8 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 PXF44736.1 - 7.5e-05 22.8 0.1 0.00036 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 PXF44736.1 - 8.6e-05 22.7 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 PXF44736.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 PXF44736.1 - 0.00014 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 PXF44736.1 - 0.00015 21.8 0.0 0.00041 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PXF44736.1 - 0.00072 19.3 0.3 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF44736.1 - 0.00093 19.6 0.3 0.0044 17.4 0.0 2.4 3 0 0 3 3 1 1 RNA helicase AAA_33 PF13671.6 PXF44736.1 - 0.001 19.2 0.1 0.005 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF44736.1 - 0.0023 18.5 0.2 0.0076 16.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 PXF44736.1 - 0.0029 18.0 0.0 0.043 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PXF44736.1 - 0.0043 17.0 0.0 1 9.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain DUF4349 PF14257.6 PXF44736.1 - 0.014 14.8 0.6 5 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Cytidylate_kin PF02224.18 PXF44736.1 - 0.019 14.7 0.5 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase DUF3450 PF11932.8 PXF44736.1 - 0.019 14.3 0.4 0.79 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Parvo_NS1 PF01057.17 PXF44736.1 - 0.021 14.0 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 PXF44736.1 - 0.024 14.3 0.0 0.45 10.2 0.0 2.7 1 1 1 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PXF44736.1 - 0.035 13.5 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PXF44736.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region Tae4 PF14113.6 PXF44736.1 - 0.073 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 ABC_tran PF00005.27 PXF44736.1 - 0.076 13.5 0.2 0.98 9.9 0.0 2.6 3 0 0 3 3 3 0 ABC transporter Use1 PF09753.9 PXF44736.1 - 0.078 12.7 4.1 0.61 9.8 4.1 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 ATPase PF06745.13 PXF44736.1 - 0.081 12.2 0.3 9.3 5.5 0.0 2.6 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 PXF44736.1 - 0.087 12.3 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 PXF44736.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 PXF44736.1 - 0.099 12.0 0.0 16 4.9 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein Torsin PF06309.11 PXF44736.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 PXF44736.1 - 0.13 11.8 0.3 0.85 9.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain Calcyon PF06387.11 PXF44736.1 - 0.14 12.1 2.0 0.3 11.1 2.0 1.5 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) ATPase_2 PF01637.18 PXF44736.1 - 0.17 11.8 2.1 2.4 8.0 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea NDC10_II PF16787.5 PXF44736.1 - 1.7 7.6 4.8 3.6 6.6 4.8 1.5 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Pkinase PF00069.25 PXF44737.1 - 1.4e-64 218.0 0.0 2.1e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44737.1 - 1.8e-31 109.4 0.0 3.4e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF44737.1 - 7.3e-07 28.4 0.2 2e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PXF44737.1 - 0.00011 21.6 0.0 0.014 14.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PXF44737.1 - 0.00033 20.6 0.3 0.17 11.8 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family SANT_DAMP1_like PF16282.5 PXF44738.1 - 4.4e-28 97.3 1.2 1.3e-25 89.4 1.2 2.5 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 PXF44738.1 - 1.9e-08 34.4 9.0 5.9e-08 32.8 0.0 3.0 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) PKcGMP_CC PF16808.5 PXF44738.1 - 0.034 14.0 1.4 0.079 12.8 1.4 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tyrosinase PF00264.20 PXF44739.1 - 1.6e-32 113.6 2.9 1.6e-32 113.6 2.9 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase Ndc1_Nup PF09531.10 PXF44739.1 - 0.074 11.7 4.0 0.099 11.3 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 PXF44740.1 - 5.7e-36 122.2 0.0 1.2e-12 47.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF44740.1 - 6.5e-05 23.0 0.0 0.093 12.9 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif ECSCR PF15820.5 PXF44741.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.1 4 1 1 5 5 5 0 Endothelial cell-specific chemotaxis regulator DUF2207 PF09972.9 PXF44741.1 - 2.4 6.8 0.0 2.4 6.8 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) SRP-alpha_N PF04086.13 PXF44743.1 - 0.026 14.4 7.9 0.044 13.7 7.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Chromo PF00385.24 PXF44744.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 PXF44744.1 - 0.012 16.0 0.0 0.099 13.1 0.0 2.2 3 0 0 3 3 3 0 PWWP domain PepSY PF03413.19 PXF44744.1 - 0.041 14.5 0.3 0.12 13.0 0.1 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Nup192 PF11894.8 PXF44746.1 - 4.8e-13 47.2 1.0 1.7e-09 35.5 0.1 2.6 3 0 0 3 3 3 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 UPF0051 PF01458.17 PXF44746.1 - 0.037 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Nup188 PF10487.9 PXF44746.1 - 0.27 9.1 0.0 0.41 8.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF1674 PF07896.12 PXF44748.1 - 3.1e-11 43.6 2.9 3.1e-11 43.6 2.9 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) Cpn60_TCP1 PF00118.24 PXF44749.1 - 5.8e-151 503.5 12.7 6.8e-151 503.2 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_dh-DNA_bdg PF14850.6 PXF44749.1 - 0.11 13.1 0.5 0.51 10.9 0.2 2.2 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase ELO PF01151.18 PXF44750.1 - 1.9e-55 188.1 21.4 2.2e-55 187.9 21.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DEAD PF00270.29 PXF44751.1 - 6.8e-51 172.5 0.0 1.4e-50 171.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF44751.1 - 8e-30 103.4 0.0 6.7e-28 97.2 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF44751.1 - 3.1e-06 27.3 0.0 6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF44751.1 - 0.011 15.4 0.0 0.067 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Xan_ur_permease PF00860.20 PXF44752.1 - 2.7e-75 253.5 27.3 3.6e-75 253.1 27.3 1.1 1 0 0 1 1 1 1 Permease family Adeno_PX PF05829.12 PXF44752.1 - 0.036 13.9 0.6 0.036 13.9 0.6 2.1 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) FliL PF03748.14 PXF44753.1 - 0.0047 17.5 0.0 0.0064 17.1 0.0 1.3 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL PAP_fibrillin PF04755.12 PXF44756.1 - 7e-09 35.9 0.0 8.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin Peptidase_S8 PF00082.22 PXF44757.1 - 8.6e-15 54.8 1.3 8.8e-14 51.4 1.3 1.9 1 1 0 1 1 1 1 Subtilase family DUF2769 PF10967.8 PXF44758.1 - 0.071 13.8 1.8 2.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) DUF3367 PF11847.8 PXF44760.1 - 0.057 11.3 0.1 0.47 8.3 0.2 1.9 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase RETICULATA-like PF11891.8 PXF44761.1 - 4.8e-15 55.8 0.1 6.3e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related FKBP_C PF00254.28 PXF44762.1 - 2.4e-10 40.6 0.1 5.2e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase POB3_N PF17292.2 PXF44763.1 - 1.1e-20 73.9 0.0 2.8e-18 66.1 0.0 2.4 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 PXF44763.1 - 1.5e-19 70.1 0.0 3.9e-18 65.6 0.1 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 PXF44763.1 - 1.9e-17 62.9 0.1 1.3e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) NIR_SIR_ferr PF03460.17 PXF44763.1 - 0.085 12.7 0.1 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain DNA_pol_phi PF04931.13 PXF44763.1 - 1.9 6.5 7.4 2.6 6.0 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 PXF44765.1 - 4.8e-36 124.4 52.5 2.7e-28 98.9 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PXF44765.1 - 0.0039 16.2 12.5 0.18 10.7 0.4 3.2 2 1 1 3 3 3 3 Nucleoside H+ symporter Pkinase_Tyr PF07714.17 PXF44767.1 - 1e-57 195.4 0.0 7.5e-54 182.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PXF44767.1 - 2.5e-53 181.1 0.0 2.6e-50 171.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 PXF44767.1 - 0.0016 17.3 0.0 0.0036 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF44767.1 - 0.006 16.0 0.6 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF44767.1 - 0.0067 16.4 2.8 0.03 14.3 0.1 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mcp5_PH PF12814.7 PXF44767.1 - 0.013 15.7 0.1 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Haspin_kinase PF12330.8 PXF44767.1 - 0.11 11.4 0.0 0.3 10.0 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_C97 PF05903.14 PXF44768.1 - 6e-36 123.5 0.0 7.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 PXF44768.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF371 PF04027.13 PXF44769.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF371) zf-Tim10_DDP PF02953.15 PXF44770.1 - 1.5e-19 69.4 3.5 1.8e-19 69.1 3.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GlutR_dimer PF00745.20 PXF44770.1 - 0.007 16.8 0.1 0.0082 16.6 0.1 1.1 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Amino_oxidase PF01593.24 PXF44771.1 - 6.6e-15 55.3 0.0 2.4e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF44771.1 - 2.9e-09 37.0 2.0 1.6e-08 34.6 1.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PXF44771.1 - 4.2e-05 22.9 0.3 0.0013 18.0 0.4 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PXF44771.1 - 5e-05 22.8 0.1 0.00025 20.5 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF44771.1 - 0.00017 20.8 3.9 0.00051 19.2 2.6 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 PXF44771.1 - 0.0002 20.7 0.1 0.00035 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PXF44771.1 - 0.00072 19.2 5.5 0.0015 18.2 4.3 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 PXF44771.1 - 0.26 10.3 0.1 2.1 7.3 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PXF44771.1 - 0.31 10.2 1.0 0.62 9.3 1.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 PXF44772.1 - 1.8e-73 247.2 0.0 2.5e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44772.1 - 1.1e-37 129.7 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF44772.1 - 7.5e-06 25.0 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF44772.1 - 0.0014 18.0 0.0 0.022 14.1 0.1 2.4 2 1 0 2 2 2 1 Kinase-like PH PF00169.29 PXF44772.1 - 0.0026 18.3 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 PH domain CLASP_N PF12348.8 PXF44773.1 - 2.7e-19 69.6 0.0 1.6e-16 60.6 0.0 2.5 2 1 0 2 2 2 2 CLASP N terminal Mago-bind PF09282.10 PXF44773.1 - 0.14 12.1 0.7 1.7 8.6 0.2 2.5 2 0 0 2 2 2 0 Mago binding CTV_P13 PF06922.11 PXF44775.1 - 0.0064 16.6 0.0 0.0076 16.3 0.0 1.0 1 0 0 1 1 1 1 Citrus tristeza virus P13 protein DDE_1 PF03184.19 PXF44776.1 - 2e-15 56.9 0.0 2.2e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF44777.1 - 0.0076 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FAE1_CUT1_RppA PF08392.12 PXF44777.1 - 0.16 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Radical_SAM PF04055.21 PXF44780.1 - 1.8e-11 44.7 0.0 3.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 PXF44780.1 - 0.00012 22.5 0.0 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family DUF1517 PF07466.11 PXF44781.1 - 1.8e-50 171.6 0.9 2.4e-50 171.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DcpS_C PF11969.8 PXF44782.1 - 8e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 PXF44782.1 - 1.6e-10 41.6 0.3 4.1e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 HIT domain RRM_1 PF00076.22 PXF44783.1 - 2.4e-12 46.5 0.0 3.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 PXF44783.1 - 5.1e-05 23.1 0.6 8.4e-05 22.4 0.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Elf1 PF05129.13 PXF44783.1 - 0.00072 19.6 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.6 PXF44783.1 - 0.0017 18.1 1.7 0.0086 15.8 1.7 2.0 1 1 1 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 PXF44783.1 - 0.008 16.3 1.3 0.99 9.6 0.3 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zinc_ribbon_9 PF14369.6 PXF44783.1 - 0.023 15.0 1.3 0.37 11.1 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon IBR PF01485.21 PXF44783.1 - 0.023 14.9 0.2 0.033 14.4 0.2 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 PXF44783.1 - 0.039 13.9 1.2 0.071 13.1 1.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.7 PXF44783.1 - 0.041 13.9 0.6 0.083 12.9 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_7 PF02591.15 PXF44783.1 - 0.096 12.9 0.7 9.9 6.4 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-DNL PF05180.12 PXF44783.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 DNL zinc finger zf-ribbon_3 PF13248.6 PXF44783.1 - 0.11 12.0 1.4 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 PXF44783.1 - 0.14 11.5 1.8 0.25 10.7 1.8 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Clat_adaptor_s PF01217.20 PXF44784.1 - 1.9e-52 177.0 0.8 2.1e-52 176.8 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCI PF01399.27 PXF44785.1 - 4.1e-08 33.7 0.1 8.9e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 PCI domain GST_C_6 PF17171.4 PXF44786.1 - 5.2e-20 71.0 0.0 1.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PXF44786.1 - 1e-14 54.9 0.2 4.8e-14 52.7 0.3 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PXF44786.1 - 8.7e-09 36.0 0.0 3.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 PXF44786.1 - 8.3e-07 28.9 0.1 2.1e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF44786.1 - 0.002 18.3 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pet127 PF08634.10 PXF44787.1 - 9.7e-74 248.2 0.5 1.3e-73 247.8 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Oxidored_FMN PF00724.20 PXF44788.1 - 7.9e-77 258.8 0.0 9.7e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Trigger_C PF05698.14 PXF44788.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Mito_carr PF00153.27 PXF44789.1 - 9.4e-16 57.5 0.0 4.8e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Romo1 PF10247.9 PXF44789.1 - 0.15 12.5 1.0 0.57 10.6 0.1 2.3 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 ECH_1 PF00378.20 PXF44793.1 - 2.3e-52 177.8 0.0 2.8e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PXF44793.1 - 1.9e-26 93.3 0.2 7.1e-26 91.5 0.1 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 PXF44794.1 - 1.3e-77 261.2 0.1 1.8e-77 260.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF44794.1 - 2.3e-09 38.1 0.5 1.1e-08 35.9 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RPE65 PF03055.15 PXF44795.1 - 6.3e-97 325.7 0.5 7.5e-97 325.4 0.5 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Aminotran_1_2 PF00155.21 PXF44796.1 - 1.9e-39 135.8 0.0 2.3e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PXF44796.1 - 0.041 12.4 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DNase-RNase PF02577.14 PXF44798.1 - 5.3e-23 81.1 0.1 1e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 PXF44798.1 - 1.9e-07 30.6 1.8 0.00076 19.1 0.0 2.7 3 0 0 3 3 3 2 UvrB/uvrC motif HSV_VP16_C PF12149.8 PXF44798.1 - 0.17 12.0 0.2 25 5.0 0.0 2.3 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal Linker_histone PF00538.19 PXF44799.1 - 4.1e-17 62.3 0.7 4.1e-17 62.3 0.7 2.2 2 1 0 2 2 2 1 linker histone H1 and H5 family Peptidase_S41_N PF11918.8 PXF44799.1 - 0.012 15.8 1.4 0.019 15.2 1.4 1.5 1 1 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF2659 PF10858.8 PXF44799.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) FSA_C PF10479.9 PXF44799.1 - 1.4 6.9 16.3 1.4 7.0 16.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PRK PF00485.18 PXF44800.1 - 1.6e-69 233.6 0.0 2.3e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PXF44800.1 - 0.0034 17.9 0.0 0.0077 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 PXF44800.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TRAPPC-Trs85 PF12739.7 PXF44801.1 - 8.3e-15 54.7 10.6 1.6e-14 53.7 10.6 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 PXF44801.1 - 5.2e-07 27.5 0.3 0.00016 19.3 1.1 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit UAA PF08449.11 PXF44802.1 - 1.6e-46 158.9 16.7 1.9e-46 158.7 16.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF44802.1 - 0.013 15.7 21.1 0.29 11.3 11.6 2.8 2 1 1 3 3 3 0 EamA-like transporter family DUF2517 PF10725.9 PXF44802.1 - 0.065 13.0 0.9 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) PIG-F PF06699.11 PXF44802.1 - 5.9 7.0 12.9 0.22 11.7 4.9 2.1 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F DUF2644 PF10841.8 PXF44802.1 - 7.2 6.9 9.6 6.3 7.1 0.5 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) Mito_carr PF00153.27 PXF44805.1 - 9.9e-25 86.3 2.3 3.1e-14 52.7 0.0 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Alpha-amylase PF00128.24 PXF44807.1 - 3.1e-15 56.6 0.0 4.5e-12 46.2 0.0 3.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 PXF44807.1 - 6.4e-10 39.3 0.0 2.2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) NinB PF05772.12 PXF44807.1 - 0.063 13.1 0.2 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 NinB protein hDGE_amylase PF14701.6 PXF44807.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain ABC_tran PF00005.27 PXF44812.1 - 4.5e-54 182.7 1.3 6.6e-27 94.7 0.0 3.2 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PXF44812.1 - 6.9e-27 93.3 9.9 2.5e-23 81.9 4.2 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 PXF44812.1 - 1.1e-11 45.1 12.2 0.0004 20.3 0.0 5.0 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF44812.1 - 7.7e-10 38.6 0.1 0.017 14.6 0.1 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PXF44812.1 - 7.9e-09 35.9 1.7 0.0048 17.2 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PXF44812.1 - 6.3e-07 29.0 0.1 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF44812.1 - 1.7e-06 28.0 12.6 0.0018 18.0 0.1 4.2 4 1 0 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 PXF44812.1 - 5.7e-06 26.4 0.2 0.046 13.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PXF44812.1 - 8e-06 25.7 0.1 0.0077 16.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PXF44812.1 - 1.2e-05 25.7 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 PXF44812.1 - 1.4e-05 25.5 0.6 0.24 11.8 0.0 3.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PXF44812.1 - 8e-05 22.6 0.1 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.15 PXF44812.1 - 0.00032 20.7 0.0 0.91 9.4 0.0 2.9 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 PXF44812.1 - 0.00034 20.9 0.6 0.37 11.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 PXF44812.1 - 0.00049 20.1 0.3 0.094 12.8 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF44812.1 - 0.00063 19.8 2.5 0.026 14.6 0.0 3.9 3 1 1 4 4 4 1 Dynamin family ATP-synt_ab PF00006.25 PXF44812.1 - 0.0019 17.9 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 PXF44812.1 - 0.0022 18.1 0.0 3.9 7.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 PXF44812.1 - 0.0042 16.5 0.0 1.6 8.0 0.0 2.9 4 0 0 4 4 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PXF44812.1 - 0.0047 16.7 0.2 2.8 7.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PXF44812.1 - 0.005 16.4 0.1 1.4 8.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 PXF44812.1 - 0.0053 16.7 0.2 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 PXF44812.1 - 0.0072 16.3 0.1 0.58 10.0 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 PXF44812.1 - 0.0081 16.5 0.1 3.1 8.2 0.0 3.2 3 0 0 3 3 2 1 RNA helicase G-alpha PF00503.20 PXF44812.1 - 0.0081 15.4 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 1 G-protein alpha subunit PRK PF00485.18 PXF44812.1 - 0.0089 15.8 0.1 9.3 5.9 0.2 3.5 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 PXF44812.1 - 0.016 15.3 0.0 2.8 8.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 PXF44812.1 - 0.021 14.6 0.1 6.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 PXF44812.1 - 0.03 14.8 2.1 2 9.0 0.1 3.5 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PXF44812.1 - 0.047 13.6 1.1 14 5.6 0.0 3.8 4 0 0 4 4 4 0 NTPase SRP54 PF00448.22 PXF44812.1 - 0.075 12.7 2.2 9.4 5.8 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PXF44812.1 - 0.088 13.3 0.1 0.088 13.3 0.1 5.1 4 2 1 5 5 4 0 AAA domain SbcCD_C PF13558.6 PXF44812.1 - 0.1 12.9 0.0 17 5.8 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 PXF44812.1 - 0.1 12.1 1.1 12 5.4 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region TsaE PF02367.17 PXF44812.1 - 0.1 12.6 0.1 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 PXF44812.1 - 0.12 12.1 0.0 35 4.1 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain tRNA-synt_1b PF00579.25 PXF44813.1 - 2.5e-88 296.2 0.0 3.1e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PRD PF00874.20 PXF44813.1 - 0.0097 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 PRD domain DUF4771 PF15995.5 PXF44813.1 - 0.039 14.2 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Mito_carr PF00153.27 PXF44814.1 - 2e-60 200.7 0.2 9.4e-21 73.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF44814.1 - 0.029 13.5 0.6 0.6 9.2 0.4 2.5 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Tfb4 PF03850.14 PXF44815.1 - 8e-66 222.3 0.2 9.3e-66 222.1 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 AbfS_sensor PF18225.1 PXF44815.1 - 0.14 12.1 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain GN3L_Grn1 PF08701.11 PXF44816.1 - 1.3e-17 63.6 16.3 2.8e-17 62.6 16.3 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 PXF44816.1 - 1.5e-17 63.7 0.0 8.5e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF44816.1 - 6.3e-08 32.3 0.2 3.8e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PXF44816.1 - 9.4e-06 25.3 0.0 0.005 16.4 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF44816.1 - 2.8e-05 24.1 0.1 0.0012 18.8 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 PXF44816.1 - 0.00018 20.9 0.0 0.024 14.0 0.0 2.5 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 PXF44816.1 - 0.00067 19.8 0.1 0.13 12.4 0.2 3.3 2 1 1 3 3 3 1 Dynamin family Pil1 PF13805.6 PXF44816.1 - 0.0041 16.7 5.3 0.0074 15.8 5.3 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 AAA_16 PF13191.6 PXF44816.1 - 0.0091 16.4 0.3 0.21 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 PXF44816.1 - 0.13 12.7 0.6 4.2 7.9 0.0 2.8 2 1 0 2 2 2 0 ABC transporter MeaB PF03308.16 PXF44816.1 - 1.6 7.7 4.0 0.99 8.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 PXF44817.1 - 1.5e-63 214.2 0.0 2.9e-63 213.2 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PXF44817.1 - 7.7e-26 90.7 0.0 2e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PXF44817.1 - 8e-13 48.9 0.0 5.1e-07 29.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PXF44817.1 - 4.7e-09 35.9 0.1 9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF44817.1 - 7.8e-09 35.7 9.8 7.8e-09 35.7 9.8 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 PXF44817.1 - 1.6e-06 28.7 42.4 1.6e-06 28.7 42.4 6.7 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PXF44817.1 - 0.064 13.8 0.0 0.064 13.8 0.0 6.3 4 3 0 4 4 4 0 ABC transporter Calici_MSP PF05752.11 PXF44817.1 - 0.45 10.3 7.1 0.12 12.2 0.9 3.0 3 0 0 3 3 3 0 Calicivirus minor structural protein DUF948 PF06103.11 PXF44817.1 - 1.5 9.1 26.7 0.19 12.0 0.4 6.2 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) FAD_binding_3 PF01494.19 PXF44818.1 - 1.8e-19 70.2 0.0 2.3e-19 69.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 PXF44818.1 - 0.11 11.5 0.6 0.16 11.0 0.3 1.4 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 PXF44818.1 - 0.19 11.0 1.1 0.33 10.2 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase rRNA_proc-arch PF13234.6 PXF44819.1 - 2.5e-60 204.7 0.1 4.4e-60 203.9 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 PXF44819.1 - 7.3e-48 162.3 0.1 1.7e-47 161.1 0.1 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PXF44819.1 - 2.8e-19 69.6 0.0 6.9e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF44819.1 - 3.6e-06 27.3 0.0 1.9e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF44819.1 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Gene66 PF02053.15 PXF44819.1 - 0.039 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein EcoEI_R_C PF08463.10 PXF44819.1 - 0.047 13.8 0.2 6.5 6.8 0.1 2.9 2 0 0 2 2 2 0 EcoEI R protein C-terminal AAA_19 PF13245.6 PXF44819.1 - 0.11 12.8 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PXF44819.1 - 0.17 11.8 3.9 0.33 10.8 0.1 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea tRNA-synt_1c PF00749.21 PXF44820.1 - 5.6e-102 340.8 0.1 7.2e-102 340.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PXF44820.1 - 2.4e-29 102.4 0.4 2e-28 99.4 0.1 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 PXF44820.1 - 0.0074 15.7 1.1 0.024 14.0 0.3 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Paf1 PF03985.13 PXF44821.1 - 3.4e-24 85.6 0.3 5.1e-24 85.1 0.3 1.3 1 0 0 1 1 1 1 Paf1 DUF1761 PF08570.10 PXF44822.1 - 3.9e-16 59.5 1.1 4.5e-16 59.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) TctB PF07331.11 PXF44822.1 - 0.72 10.1 6.1 0.21 11.8 2.1 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1761 PF08570.10 PXF44823.1 - 3.8e-16 59.5 3.8 4.4e-16 59.3 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Bromodomain PF00439.25 PXF44824.1 - 6.5e-18 64.6 0.0 1.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 PXF44825.1 - 6.9e-21 74.1 1.1 5.3e-20 71.3 0.0 2.8 3 0 0 3 3 3 1 Bromodomain GATA PF00320.27 PXF44825.1 - 2.4e-06 27.0 4.2 4.9e-06 26.0 4.2 1.6 1 0 0 1 1 1 1 GATA zinc finger Phage-scaffold PF09306.10 PXF44825.1 - 0.082 12.3 2.0 0.19 11.1 2.0 1.5 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein RPA_interact_N PF14766.6 PXF44825.1 - 0.51 10.0 3.5 1.2 8.8 3.5 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal RNase_PH PF01138.21 PXF44826.1 - 1.6e-21 77.2 0.4 2.3e-21 76.7 0.4 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF44826.1 - 0.056 13.5 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ArAE_2_N PF10337.9 PXF44827.1 - 7 5.6 10.9 11 4.9 10.9 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal RNase_PH PF01138.21 PXF44829.1 - 5.4e-20 72.2 0.3 7.9e-20 71.7 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF44829.1 - 0.065 13.3 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ArAE_2_N PF10337.9 PXF44830.1 - 7 5.6 10.9 11 4.9 10.9 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal TetR_C_20 PF17925.1 PXF44831.1 - 0.041 14.2 0.1 0.069 13.5 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 PXF44832.1 - 1e-20 74.1 0.0 2.8e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 PXF44832.1 - 1.2e-07 31.8 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 PXF44832.1 - 2.1e-07 30.8 0.0 3.3e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PXF44832.1 - 0.00031 20.3 0.1 0.0027 17.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PXF44832.1 - 0.0059 16.9 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 PXF44832.1 - 0.048 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PXF44832.1 - 0.061 12.5 0.1 0.72 9.0 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.23 PXF44832.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ArAE_2_N PF10337.9 PXF44833.1 - 8.7 5.2 11.6 14 4.6 11.6 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal UTP15_C PF09384.10 PXF44835.1 - 1.3e-34 119.0 0.0 2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 PXF44835.1 - 2.2e-18 66.3 10.7 3.9e-07 30.6 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF44835.1 - 5.6e-08 33.0 0.0 0.057 13.7 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.11 PXF44835.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Ge1_WD40 PF16529.5 PXF44835.1 - 0.039 12.9 0.1 2.9 6.8 0.0 2.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PXF44835.1 - 0.25 11.9 0.9 54 4.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Rep_fac-A_C PF08646.10 PXF44836.1 - 2.4e-32 111.7 0.0 3.7e-28 98.1 0.0 2.5 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.12 PXF44836.1 - 9.6e-26 89.8 0.1 2.6e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain REPA_OB_2 PF16900.5 PXF44836.1 - 1.3e-20 73.2 0.0 3.3e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 PXF44836.1 - 8.4e-11 41.7 0.1 4.2e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Peptidase_M16_M PF16187.5 PXF44836.1 - 0.16 11.3 0.1 0.51 9.6 0.1 1.8 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 A_deaminase PF00962.22 PXF44837.1 - 7.3e-27 94.6 0.0 9.1e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase T4_Rnl2_C PF18043.1 PXF44837.1 - 0.12 12.5 0.2 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal DUF1664 PF07889.12 PXF44838.1 - 2.2e-14 53.6 2.4 2.7e-14 53.3 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PXF44838.1 - 4.7e-06 27.0 1.2 0.022 15.2 0.3 3.3 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 PXF44838.1 - 2.5e-05 24.3 0.0 0.00054 20.0 0.0 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 PXF44838.1 - 0.0007 19.0 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Prefoldin_3 PF13758.6 PXF44838.1 - 0.0049 16.9 0.1 5 7.3 0.3 2.8 2 1 0 2 2 2 2 Prefoldin subunit DUF4349 PF14257.6 PXF44838.1 - 0.009 15.5 1.2 0.076 12.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) CLZ PF16526.5 PXF44838.1 - 0.011 16.0 0.0 1.6 9.1 0.0 3.2 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels T3SSipB PF16535.5 PXF44838.1 - 0.014 15.9 0.7 0.1 13.1 0.0 2.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB DUF948 PF06103.11 PXF44838.1 - 0.031 14.5 3.6 2.2 8.6 1.3 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LPP PF04728.13 PXF44838.1 - 0.081 13.3 6.1 2.6 8.5 0.5 4.0 3 2 2 5 5 5 0 Lipoprotein leucine-zipper EspB PF05802.11 PXF44838.1 - 0.097 12.7 4.7 2.1 8.3 1.2 2.3 2 0 0 2 2 2 0 Enterobacterial EspB protein Fib_alpha PF08702.10 PXF44838.1 - 0.12 12.6 0.1 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 PXF44838.1 - 0.18 12.2 0.2 15 6.0 0.0 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 PXF44838.1 - 1.4 9.3 7.1 0.44 10.9 0.2 2.8 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Med11 PF10280.9 PXF44839.1 - 7.7e-07 29.7 0.1 9.6e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Mediator complex protein DUF4831 PF16115.5 PXF44839.1 - 0.039 13.0 0.2 0.053 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) SLBP_RNA_bind PF15247.6 PXF44840.1 - 7.7e-24 83.6 1.8 7.7e-24 83.6 1.8 1.6 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain RPN7 PF10602.9 PXF44841.1 - 1.2e-27 96.7 0.1 2.5e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PXF44841.1 - 3.7e-13 49.9 0.2 9.3e-13 48.6 0.2 1.7 1 0 0 1 1 1 1 PCI domain dsDNA_bind PF01984.20 PXF44841.1 - 0.98 9.7 3.7 0.21 11.9 0.3 1.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain ANAPC4_WD40 PF12894.7 PXF44842.1 - 0.077 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF44842.1 - 0.12 13.3 1.9 0.47 11.4 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat CRT10 PF08728.10 PXF44842.1 - 0.31 9.2 2.3 0.75 7.9 2.3 1.5 1 1 0 1 1 1 0 CRT10 Gln-synt_C PF00120.24 PXF44843.1 - 8.6e-18 64.4 0.0 2.3e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PXF44843.1 - 1.8e-09 37.2 0.0 3.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VapB_antitoxin PF09957.9 PXF44844.1 - 0.4 10.6 1.6 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB SPT16 PF08644.11 PXF44844.1 - 1.5 9.0 4.4 2.4 8.3 2.2 2.3 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DIE2_ALG10 PF04922.12 PXF44845.1 - 2.9e-77 260.6 15.1 2.6e-75 254.1 15.1 2.1 1 1 0 1 1 1 1 DIE2/ALG10 family MRP_L53 PF10780.9 PXF44846.1 - 1.5e-08 34.7 0.4 3.3e-08 33.6 0.0 1.8 3 0 0 3 3 3 1 39S ribosomal protein L53/MRP-L53 C2 PF00168.30 PXF44847.1 - 3.6e-12 46.5 0.0 6.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain UQ_con PF00179.26 PXF44848.1 - 1.1e-41 141.8 0.0 1.2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF44848.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Ribosomal_S16 PF00886.19 PXF44849.1 - 1.8e-26 92.0 0.1 2.5e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 60KD_IMP PF02096.20 PXF44850.1 - 0.0002 21.3 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 60Kd inner membrane protein NCOA_u2 PF16665.5 PXF44850.1 - 0.028 14.7 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein Alpha-amylase PF00128.24 PXF44851.1 - 3.4e-24 86.0 0.0 9.3e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain HisKA PF00512.25 PXF44851.1 - 0.1 12.7 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain GSHPx PF00255.19 PXF44852.1 - 6.6e-23 80.4 0.2 2.5e-22 78.5 0.1 1.8 2 0 0 2 2 2 1 Glutathione peroxidase SMC_ScpB PF04079.16 PXF44852.1 - 0.083 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Spond_N PF06468.13 PXF44853.1 - 3.2e-27 95.9 0.0 3.9e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Spond_N PF06468.13 PXF44854.1 - 1.5e-27 97.0 0.0 1.8e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Spondin_N CNDH2_C PF16858.5 PXF44855.1 - 1.6e-34 120.1 0.1 5.1e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 PXF44855.1 - 9.2e-28 96.7 1.1 2.4e-27 95.3 1.1 1.8 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Rad21_Rec8_N PF04825.13 PXF44855.1 - 0.0086 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein TBP PF00352.21 PXF44856.1 - 3.3e-65 216.0 0.4 2.4e-31 107.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PXF44856.1 - 5.4e-07 29.6 0.0 0.0026 17.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 PXF44856.1 - 0.073 12.9 0.2 0.52 10.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Ribosomal_L24e PF01246.20 PXF44857.1 - 4.5e-27 94.1 0.4 1.2e-26 92.7 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e FYRC PF05965.14 PXF44857.1 - 0.23 11.6 0.8 0.41 10.8 0.3 1.6 1 1 0 1 1 1 0 F/Y rich C-terminus Pkinase PF00069.25 PXF44860.1 - 1.6e-70 237.5 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44860.1 - 4.3e-39 134.4 0.0 6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF44860.1 - 9.9e-05 21.8 0.0 0.0011 18.3 0.0 2.4 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF44860.1 - 0.00017 21.6 0.1 0.0028 17.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF44860.1 - 0.021 13.8 0.1 0.058 12.3 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 PXF44860.1 - 0.053 13.1 1.2 0.094 12.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 PXF44860.1 - 0.089 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2526 PF10735.9 PXF44860.1 - 0.11 12.6 1.1 0.3 11.3 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) SMP_LBD PF17047.5 PXF44861.1 - 6.6e-29 100.7 0.2 8.9e-29 100.2 0.2 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 PXF44861.1 - 9.3e-15 54.8 0.0 3.9e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 C2 domain RCC1 PF00415.18 PXF44862.1 - 4e-49 165.0 7.6 1.6e-12 47.9 0.1 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF44862.1 - 6.9e-21 73.5 18.3 7e-10 38.4 0.8 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 PXF44862.1 - 0.0057 16.9 2.8 90 3.4 0.0 4.8 4 1 1 5 5 5 0 Putative heavy-metal chelation PapC_C PF13953.6 PXF44862.1 - 0.012 15.5 0.1 0.66 9.8 0.0 2.8 2 0 0 2 2 2 0 PapC C-terminal domain Presenilin PF01080.17 PXF44862.1 - 0.077 11.7 4.6 0.12 11.1 4.6 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PXF44862.1 - 4.8 5.7 7.8 5.9 5.4 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RPN2_C PF18004.1 PXF44863.1 - 5.6e-32 110.9 5.8 5.6e-32 110.9 5.8 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 PXF44863.1 - 2.1e-18 65.8 32.3 0.0017 18.7 0.0 8.8 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PXF44863.1 - 2.9e-18 66.0 0.3 6.8e-13 48.8 0.0 4.4 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 PXF44863.1 - 3.7e-07 29.8 1.8 1.3 9.5 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 PXF44863.1 - 7.6e-05 23.1 0.6 0.0034 17.8 0.1 4.0 3 1 1 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 PXF44863.1 - 0.17 11.4 0.0 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal Ribosomal_S8e PF01201.22 PXF44864.1 - 1.7e-53 180.5 0.1 2.1e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e PHD PF00628.29 PXF44865.1 - 2.6e-09 36.8 7.3 4.8e-09 36.0 7.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PXF44865.1 - 0.018 14.6 1.8 0.029 13.9 1.8 1.3 1 0 0 1 1 1 0 PHD-finger Borrelia_rep PF03183.13 PXF44865.1 - 0.63 10.1 2.5 2 8.6 2.5 1.9 1 0 0 1 1 1 0 Borrelia repeat protein DUF647 PF04884.14 PXF44866.1 - 5.4e-71 239.0 0.2 7e-71 238.7 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Nitr_red_bet_C PF14711.6 PXF44866.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Apo-CII PF05355.11 PXF44868.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Apolipoprotein C-II Serine_rich PF08824.10 PXF44868.1 - 0.031 14.3 0.1 0.038 14.0 0.1 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF4449 PF14613.6 PXF44868.1 - 0.037 14.1 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF2433 PF10360.9 PXF44868.1 - 0.046 13.8 0.0 0.16 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) Apolipoprotein PF01442.18 PXF44868.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PMC2NT PF08066.12 PXF44868.1 - 0.079 13.7 0.3 0.17 12.6 0.2 1.7 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Cas_APE2256 PF09651.10 PXF44868.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) ApoLp-III PF07464.11 PXF44868.1 - 0.14 12.2 1.5 1.5 8.9 0.4 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SRP54 PF00448.22 PXF44869.1 - 5.5e-75 251.3 1.4 1.2e-74 250.2 1.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PXF44869.1 - 1.3e-23 83.4 1.5 1.3e-23 83.4 1.5 3.7 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 PXF44869.1 - 6.6e-17 61.5 0.6 6.6e-17 61.5 0.6 3.1 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 PXF44869.1 - 2.5e-07 30.2 0.1 5.6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 PXF44869.1 - 0.00017 21.4 2.3 0.00035 20.4 1.3 2.2 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 PXF44869.1 - 0.00019 21.3 0.2 0.00058 19.8 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase CbiA PF01656.23 PXF44869.1 - 0.00022 21.3 0.0 0.001 19.1 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 PXF44869.1 - 0.0018 17.9 1.5 0.0057 16.3 1.5 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 PXF44869.1 - 0.0022 18.4 0.3 0.0022 18.4 0.3 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PXF44869.1 - 0.0035 17.7 0.1 0.008 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 PXF44869.1 - 0.012 15.1 0.2 0.043 13.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PXF44869.1 - 0.013 15.2 0.9 0.06 13.1 0.8 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 PXF44869.1 - 0.018 15.2 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PXF44869.1 - 0.044 14.2 1.5 0.65 10.4 0.1 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 PXF44869.1 - 0.075 12.2 0.0 0.075 12.2 0.0 3.4 5 0 0 5 5 5 0 Anion-transporting ATPase AAA_18 PF13238.6 PXF44869.1 - 0.12 12.9 0.1 0.34 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 PXF44870.1 - 0.00062 18.7 15.5 0.00062 18.7 15.5 4.2 2 2 2 4 4 4 3 Spc7 kinetochore protein DMPK_coil PF08826.10 PXF44870.1 - 0.016 15.3 4.4 0.016 15.3 4.4 5.6 5 2 1 6 6 6 0 DMPK coiled coil domain like DUF5069 PF16798.5 PXF44870.1 - 0.71 10.1 6.6 0.13 12.5 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) DASH_Dam1 PF08653.10 PXF44870.1 - 1.8 8.4 5.8 3.5 7.5 0.0 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 CALCOCO1 PF07888.11 PXF44870.1 - 6.1 5.6 66.7 0.039 12.8 24.6 3.0 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ribosomal_S7 PF00177.21 PXF44871.1 - 1.7e-37 128.4 0.9 2e-37 128.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Hint PF01079.20 PXF44872.1 - 2.9e-28 98.9 0.2 8.3e-28 97.4 0.2 1.7 1 1 0 1 1 1 1 Hint module AdoHcyase PF05221.17 PXF44873.1 - 6.5e-141 468.7 0.0 7.4e-141 468.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PXF44873.1 - 2.8e-81 271.3 1.7 4.3e-81 270.7 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF44873.1 - 4e-09 36.1 0.2 7.2e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PXF44873.1 - 8.9e-06 25.4 0.2 1.4e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 PXF44873.1 - 4.4e-05 23.6 0.3 0.00011 22.3 0.3 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PXF44873.1 - 0.0002 21.7 0.2 0.00058 20.3 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 PXF44873.1 - 0.0045 16.3 1.8 0.012 15.0 1.8 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 PXF44873.1 - 0.0049 17.1 0.1 0.024 14.9 0.1 2.2 2 1 0 2 2 2 1 TrkA-N domain ELFV_dehydrog PF00208.21 PXF44873.1 - 0.012 15.4 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 PXF44873.1 - 0.022 13.5 0.6 0.97 8.1 0.1 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase XdhC_C PF13478.6 PXF44873.1 - 0.071 13.6 0.3 0.26 11.8 0.1 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain Urocanase PF01175.18 PXF44873.1 - 0.1 12.2 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF4793 PF16041.5 PXF44874.1 - 0.17 12.0 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) zf-C2H2 PF00096.26 PXF44875.1 - 2.6e-17 62.2 24.8 5.6e-06 26.5 1.4 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF44875.1 - 8.3e-16 57.3 25.8 0.00043 20.9 1.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF44875.1 - 3.9e-15 55.5 22.0 0.00012 22.4 0.8 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_11 PF16622.5 PXF44875.1 - 2.6e-09 36.7 19.7 0.0035 17.1 1.0 4.3 4 0 0 4 4 4 4 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PXF44875.1 - 9.6e-08 32.1 15.5 0.37 11.1 0.6 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PXF44875.1 - 0.00012 22.8 12.1 0.052 14.2 7.1 3.5 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 PXF44875.1 - 0.0013 18.4 0.7 0.0013 18.4 0.7 5.0 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-AN1 PF01428.16 PXF44875.1 - 0.0015 18.7 12.2 2.3 8.4 0.2 4.4 4 1 0 4 4 4 1 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 PXF44875.1 - 0.0039 17.3 13.2 0.83 9.8 3.3 3.8 3 1 1 4 4 4 2 Zinc ribbon domain zf-met PF12874.7 PXF44875.1 - 0.0074 16.7 16.5 0.29 11.6 0.2 3.8 4 0 0 4 4 3 2 Zinc-finger of C2H2 type DZR PF12773.7 PXF44875.1 - 0.016 15.3 11.5 16 5.7 11.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 PXF44875.1 - 0.016 15.1 14.6 0.38 10.7 1.7 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type C1_1 PF00130.22 PXF44875.1 - 0.016 15.0 14.3 1.1 9.2 2.1 3.6 1 1 3 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAGA PF09237.11 PXF44875.1 - 0.028 14.2 4.0 1.4 8.8 0.6 2.5 2 1 0 2 2 2 0 GAGA factor BolA PF01722.18 PXF44875.1 - 0.036 14.3 0.6 1.9 8.8 0.1 2.4 1 1 1 2 2 2 0 BolA-like protein zf-BED PF02892.15 PXF44875.1 - 0.046 13.8 22.2 0.055 13.5 2.6 4.1 3 1 1 4 4 4 0 BED zinc finger ADK_lid PF05191.14 PXF44875.1 - 0.093 12.7 7.9 3.7 7.6 1.6 3.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid KELK PF15796.5 PXF44875.1 - 0.17 12.4 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zinc_ribbon_15 PF17032.5 PXF44875.1 - 0.17 12.6 12.9 5.8 7.7 7.6 2.9 1 1 2 3 3 3 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 PXF44875.1 - 0.18 11.5 9.0 0.95 9.2 0.0 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain HypA PF01155.19 PXF44875.1 - 0.23 11.5 10.2 1.5 8.8 0.8 2.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3 PF13878.6 PXF44875.1 - 0.23 11.3 8.6 1 9.2 0.3 3.8 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf_UBZ PF18439.1 PXF44875.1 - 0.36 10.4 10.0 12 5.6 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 PXF44875.1 - 0.39 11.4 7.7 24 5.7 0.8 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain PyrI_C PF02748.15 PXF44875.1 - 0.49 10.3 11.2 32 4.5 0.2 4.0 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain XPA_N PF01286.18 PXF44875.1 - 0.53 10.4 9.9 21 5.2 0.0 4.1 4 0 0 4 4 4 0 XPA protein N-terminal FdhD-NarQ PF02634.15 PXF44875.1 - 0.54 9.9 5.3 0.29 10.8 0.9 1.9 1 1 1 2 2 2 0 FdhD/NarQ family zf-C2H2_8 PF15909.5 PXF44875.1 - 0.63 10.4 13.3 0.22 11.9 4.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon PriA_CRR PF18319.1 PXF44875.1 - 0.67 10.0 15.6 2.4 8.2 1.1 4.3 4 0 0 4 4 4 0 PriA DNA helicase Cys-rich region (CRR) domain zf-nanos PF05741.13 PXF44875.1 - 1 9.6 16.4 1.4 9.2 0.2 4.1 1 1 2 3 3 3 0 Nanos RNA binding domain DUF2197 PF09963.9 PXF44875.1 - 1.6 9.1 8.5 1.5 9.1 0.6 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2HE PF16278.5 PXF44875.1 - 1.7 9.2 18.0 3.1 8.3 3.2 4.0 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 PXF44875.1 - 2 8.8 17.2 1 9.7 1.1 3.7 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 PXF44875.1 - 3.9 8.2 5.4 90 3.8 0.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-trcl PF13451.6 PXF44875.1 - 6 6.9 12.0 30 4.6 3.0 3.7 2 1 2 4 4 4 0 Probable zinc-ribbon domain zf-C2H2_6 PF13912.6 PXF44875.1 - 7.4 6.7 26.9 1.1 9.3 1.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DnaJ PF00226.31 PXF44876.1 - 1.5e-20 73.1 0.9 3.6e-20 71.9 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain Flu_M2 PF00599.17 PXF44876.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M2) DUF1087 PF06465.13 PXF44876.1 - 0.098 12.7 1.4 0.31 11.1 1.4 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Copine PF07002.16 PXF44877.1 - 1.8e-53 181.2 0.0 3.3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 PXF44877.1 - 8.7e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 PXF44877.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus SBBP PF06739.11 PXF44879.1 - 0.0047 16.9 8.1 0.92 9.6 0.7 3.5 3 0 0 3 3 3 2 Beta-propeller repeat AMP-binding PF00501.28 PXF44881.1 - 2e-75 254.0 0.0 2.5e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF44881.1 - 3.4e-17 63.2 0.0 9.1e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 PXF44881.1 - 0.015 14.2 0.0 0.033 13.0 0.1 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DRTGG PF07085.12 PXF44881.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.8 1 0 0 1 1 1 0 DRTGG domain DDE_1 PF03184.19 PXF44882.1 - 7.1e-12 45.3 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 PXF44882.1 - 0.093 12.5 0.0 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 DDE superfamily endonuclease HPIP PF15226.6 PXF44882.1 - 0.096 13.1 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family HTH_42 PF06224.12 PXF44883.1 - 0.048 13.2 0.3 0.06 12.9 0.3 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain PAE PF03283.13 PXF44885.1 - 0.026 13.7 0.0 0.35 9.9 0.0 2.0 2 0 0 2 2 2 0 Pectinacetylesterase Spond_N PF06468.13 PXF44886.1 - 1.8e-29 103.2 0.0 2.3e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Spondin_N THUMP PF02926.17 PXF44887.1 - 3.2e-11 43.5 1.1 3.2e-11 43.5 1.1 1.7 2 0 0 2 2 2 1 THUMP domain ABC_membrane PF00664.23 PXF44888.1 - 9.4e-110 366.6 18.5 6.1e-60 203.2 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF44888.1 - 7.2e-68 227.4 0.0 1.1e-32 113.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PXF44888.1 - 4.6e-11 42.6 1.1 0.0012 18.4 0.1 4.2 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PXF44888.1 - 8.5e-07 28.1 0.1 0.017 13.9 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 PXF44888.1 - 5.8e-06 26.8 0.8 0.16 12.3 0.2 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 PXF44888.1 - 2.4e-05 24.6 0.4 0.65 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PXF44888.1 - 4.6e-05 23.4 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PXF44888.1 - 0.00024 20.8 0.3 0.39 10.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF44888.1 - 0.00045 20.0 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 PXF44888.1 - 0.0017 18.9 0.0 0.39 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PXF44888.1 - 0.0017 17.7 0.1 0.59 9.4 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 PXF44888.1 - 0.0021 18.2 0.0 0.55 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PXF44888.1 - 0.0038 17.6 0.2 5.8 7.4 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 PXF44888.1 - 0.0057 16.9 2.4 1.2 9.4 0.3 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 PXF44888.1 - 0.0066 16.0 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 PXF44888.1 - 0.0068 16.4 0.0 2.8 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PXF44888.1 - 0.0091 15.7 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF44888.1 - 0.015 15.7 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 PXF44888.1 - 0.02 14.4 0.8 12 5.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 PXF44888.1 - 0.031 14.3 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 PXF44888.1 - 0.035 13.8 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 PXF44888.1 - 0.054 13.2 0.1 17 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 PXF44888.1 - 0.089 12.7 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_21 PF13304.6 PXF44888.1 - 0.15 11.9 0.0 17 5.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 PXF44888.1 - 0.16 12.0 3.8 4.1 7.4 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain PPR_2 PF13041.6 PXF44889.1 - 4.3e-60 199.7 3.2 6.9e-15 55.0 0.1 8.1 3 2 6 9 9 9 6 PPR repeat family PPR PF01535.20 PXF44889.1 - 6.3e-55 179.7 2.9 2.8e-07 30.3 0.0 9.4 9 0 0 9 9 9 7 PPR repeat PPR_3 PF13812.6 PXF44889.1 - 1.2e-54 182.2 1.1 1.3e-13 50.8 0.0 7.0 2 1 6 9 9 9 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF44889.1 - 1.9e-49 165.0 0.0 7.3e-09 35.2 0.0 7.6 7 0 0 7 7 7 7 PPR repeat PPR_long PF17177.4 PXF44889.1 - 3.5e-33 114.8 0.0 3e-16 59.5 0.0 3.2 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 PXF44889.1 - 3.2e-05 23.0 0.0 0.12 11.2 0.0 3.9 1 1 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 PXF44889.1 - 0.0013 19.4 0.1 5.6 8.1 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat RPM2 PF08579.11 PXF44889.1 - 0.0013 19.1 0.4 46 4.5 0.0 4.5 2 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Clathrin PF00637.20 PXF44889.1 - 0.019 14.8 0.4 15 5.4 0.1 3.7 1 1 1 3 3 3 0 Region in Clathrin and VPS ADK PF00406.22 PXF44889.1 - 0.15 12.1 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase Rgp1 PF08737.10 PXF44890.1 - 4.5e-30 105.2 0.0 1.5e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 PXF44890.1 - 0.051 13.6 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PXF44890.1 - 0.066 13.7 0.0 9.9 6.6 0.0 3.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain DUF599 PF04654.12 PXF44890.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Ribosomal_L30 PF00327.20 PXF44891.1 - 3e-15 55.8 0.2 4e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-RING_2 PF13639.6 PXF44892.1 - 1.4e-09 38.1 10.5 1.4e-09 38.1 10.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF44892.1 - 7.5e-08 32.0 6.4 7.5e-08 32.0 6.4 2.4 3 0 0 3 3 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF44892.1 - 1.5e-05 25.2 6.4 1.5e-05 25.2 6.4 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF44892.1 - 4.2e-05 23.4 7.0 7.9e-05 22.5 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF44892.1 - 6.9e-05 22.6 7.6 0.00014 21.6 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF44892.1 - 0.00016 21.2 4.7 0.0003 20.4 4.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PXF44892.1 - 0.00029 20.8 5.9 0.00081 19.4 5.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF44892.1 - 0.00029 20.6 9.0 0.00056 19.7 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF44892.1 - 0.00052 19.8 10.9 0.00063 19.5 9.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.8 PXF44892.1 - 0.0085 14.0 0.8 0.018 12.9 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 PXF44892.1 - 0.045 13.8 2.8 0.1 12.7 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PXF44892.1 - 0.49 10.3 8.5 0.9 9.4 8.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 PXF44892.1 - 0.51 10.5 8.8 1.1 9.5 8.8 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PXF44892.1 - 1.9 8.7 5.0 4.7 7.5 5.0 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 PXF44892.1 - 3.2 7.5 10.6 0.38 10.4 1.3 3.1 2 1 1 3 3 3 0 P-11 zinc finger Spond_N PF06468.13 PXF44893.1 - 6.3e-27 94.9 0.0 7.4e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Spondin_N zf-C2H2 PF00096.26 PXF44896.1 - 6.1e-09 35.8 27.9 0.015 15.7 1.2 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF44896.1 - 1.9e-05 24.9 34.1 0.01 16.2 2.1 5.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF44896.1 - 0.0014 19.3 38.2 0.091 13.6 0.9 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger CFC PF09443.10 PXF44896.1 - 0.023 14.5 0.2 0.023 14.5 0.2 4.1 5 0 0 5 5 5 0 Cripto_Frl-1_Cryptic (CFC) zf-C2H2_jaz PF12171.8 PXF44896.1 - 1.6 9.1 15.7 2.1 8.7 0.4 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 PXF44896.1 - 1.8 9.2 32.1 0.18 12.5 2.1 4.3 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 PXF44896.1 - 7.2 5.0 14.8 4.5 5.7 1.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 PXF44896.1 - 9 6.8 21.8 0.15 12.6 1.5 4.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF92 PF01940.16 PXF44897.1 - 3.4e-65 219.8 6.0 3.9e-65 219.6 6.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF599 PF04654.12 PXF44897.1 - 0.059 12.8 1.8 0.096 12.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Iron_permease PF04120.12 PXF44897.1 - 0.11 12.2 1.0 0.22 11.3 1.0 1.4 1 0 0 1 1 1 0 Low affinity iron permease DUF4934 PF16288.5 PXF44897.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) PMT PF02366.18 PXF44899.1 - 1e-35 123.5 14.0 1e-35 123.5 14.0 2.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PXF44899.1 - 1.9e-35 122.3 17.3 1.9e-35 122.3 17.3 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase Alba PF01918.21 PXF44900.1 - 1.7e-10 40.5 0.1 2.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 PXF44900.1 - 0.0077 16.2 0.2 0.011 15.6 0.2 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P PALP PF00291.25 PXF44901.1 - 7.6e-52 176.5 1.9 1e-51 176.1 1.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAP2 PF01569.21 PXF44903.1 - 2e-07 30.9 8.8 2e-07 30.9 8.8 3.2 2 1 1 3 3 3 1 PAP2 superfamily DUF212 PF02681.14 PXF44903.1 - 0.02 15.0 0.6 0.49 10.5 0.1 2.4 1 1 1 2 2 2 0 Divergent PAP2 family DUF3421 PF11901.8 PXF44904.1 - 8.7e-39 132.1 1.2 2e-20 72.9 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) VWA PF00092.28 PXF44908.1 - 1.8e-16 60.9 0.2 2.6e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44908.1 - 2.1e-07 31.6 0.1 4.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF44908.1 - 0.0022 18.0 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain HWE_HK PF07536.14 PXF44909.1 - 0.043 14.5 0.4 0.44 11.3 0.0 2.9 3 1 0 3 3 3 0 HWE histidine kinase DUF963 PF06131.11 PXF44910.1 - 0.0051 16.2 12.5 0.0051 16.2 12.5 4.8 3 1 0 3 3 3 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) zinc_ribbon_12 PF11331.8 PXF44911.1 - 0.026 14.3 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain PPO1_DWL PF12142.8 PXF44911.1 - 0.14 11.9 0.8 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 Polyphenol oxidase middle domain ArgJ PF01960.18 PXF44912.1 - 0.081 11.6 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 ArgJ family Mating_N PF12731.7 PXF44913.1 - 0.017 15.2 0.2 0.027 14.6 0.1 1.4 1 1 0 1 1 1 0 Mating-type protein beta 1 DDE_1 PF03184.19 PXF44914.1 - 3.9e-18 65.7 0.0 5.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease LPMO_10 PF03067.15 PXF44916.1 - 9.2e-16 59.1 0.4 1.4e-15 58.5 0.4 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Big_7 PF17957.1 PXF44916.1 - 0.00075 20.2 0.6 0.0048 17.6 0.0 2.2 1 1 0 2 2 2 1 Bacterial Ig domain Ephrin_rec_like PF07699.13 PXF44917.1 - 5.3e-11 42.1 63.3 4.8e-05 23.0 5.1 7.8 4 2 4 8 8 8 6 Putative ephrin-receptor like NCD3G PF07562.14 PXF44917.1 - 3e-07 30.3 48.3 0.0037 17.2 2.2 7.5 5 2 3 8 8 8 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PXF44917.1 - 0.061 13.7 0.1 0.061 13.7 0.1 9.9 6 3 3 10 10 10 0 TNFR/NGFR cysteine-rich region Nup214_FG PF18617.1 PXF44917.1 - 0.11 13.1 0.1 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Suf PF05843.14 PXF44920.1 - 1.3e-40 140.3 0.0 2.3e-33 116.4 0.0 2.9 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_16 PF13432.6 PXF44920.1 - 5.4e-07 30.2 0.7 0.0097 16.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF44920.1 - 5.7e-07 29.8 7.1 0.48 11.4 0.0 7.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF44920.1 - 5.5e-06 26.8 0.0 0.18 12.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 PXF44920.1 - 0.014 14.6 3.4 0.51 9.4 0.0 3.9 2 1 2 5 5 5 0 NRDE-2, necessary for RNA interference PFK PF00365.20 PXF44921.1 - 2.9e-40 138.4 0.0 1e-39 136.6 0.0 1.8 2 0 0 2 2 2 1 Phosphofructokinase LYTB PF02401.18 PXF44921.1 - 0.18 11.1 0.2 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 LytB protein FAD_binding_1 PF00667.20 PXF44922.1 - 5e-25 88.4 0.5 8.8e-25 87.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 PXF44922.1 - 5.5e-19 68.8 0.0 1.6e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 PXF44922.1 - 8.9e-19 68.1 0.0 1.6e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 PXF44922.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain TPR_14 PF13428.6 PXF44923.1 - 2.8e-27 93.1 35.6 0.0003 21.4 0.2 10.1 3 2 8 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 PXF44923.1 - 1.1e-25 87.7 22.3 0.002 18.1 0.1 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 PXF44923.1 - 7.8e-21 74.4 1.9 9.2e-06 26.1 0.0 6.4 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 PXF44923.1 - 6.9e-13 47.8 4.0 0.11 12.4 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF44923.1 - 8.1e-11 41.2 0.0 1.6 9.1 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF44923.1 - 1.5e-10 41.5 31.5 8.4e-05 23.1 0.6 7.4 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF44923.1 - 1.3e-09 38.2 18.4 0.00016 21.9 0.2 8.1 5 1 3 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF44923.1 - 2.7e-09 37.1 7.9 1.8 8.6 0.0 8.2 7 2 2 9 9 9 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 PXF44923.1 - 4.5e-09 36.1 0.0 1.2 9.7 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF44923.1 - 5.7e-07 29.1 5.9 1.3 9.3 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF44923.1 - 3.4e-06 26.5 18.0 0.021 14.1 0.1 5.4 1 1 2 4 4 4 3 Tetratricopeptide repeat PPR PF01535.20 PXF44923.1 - 2.6e-05 24.2 0.8 0.65 10.4 0.0 5.5 8 0 0 8 8 4 1 PPR repeat TPR_11 PF13414.6 PXF44923.1 - 0.00032 20.3 0.0 2.9 7.7 0.0 4.4 5 0 0 5 5 4 1 TPR repeat Suf PF05843.14 PXF44923.1 - 0.00039 20.5 3.5 2 8.3 0.1 4.3 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_9 PF13371.6 PXF44923.1 - 0.0013 18.8 13.0 0.76 10.0 0.1 4.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF44923.1 - 0.003 18.1 18.7 16 6.4 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF3887 PF13026.6 PXF44923.1 - 0.076 13.8 1.5 13 6.7 0.0 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF3887) DUF2802 PF10975.8 PXF44923.1 - 0.11 12.6 0.4 15 5.8 0.0 3.8 5 0 0 5 5 4 0 Protein of unknown function (DUF2802) MIT PF04212.18 PXF44923.1 - 0.12 12.4 1.8 65 3.7 0.0 4.6 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain FAT PF02259.23 PXF44923.1 - 0.21 10.8 18.2 0.21 10.8 0.3 4.8 2 2 1 4 4 4 0 FAT domain TOM20_plant PF06552.12 PXF44923.1 - 0.26 11.0 1.7 11 5.7 0.0 3.8 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 PXF44923.1 - 9.7 6.2 17.3 20 5.2 0.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 PXF44924.1 - 1e-20 74.3 0.1 1.6e-20 73.7 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Clathrin_lg_ch PF01086.17 PXF44924.1 - 1.8e-17 64.2 0.0 2.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Clathrin light chain NAC PF01849.18 PXF44925.1 - 4.1e-23 81.1 4.9 2.4e-22 78.7 0.4 3.2 3 0 0 3 3 3 1 NAC domain MRG PF05712.13 PXF44926.1 - 1.6e-38 132.0 0.0 3.3e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 PXF44926.1 - 2.9e-06 27.1 0.0 6.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Peptidase_M48 PF01435.18 PXF44927.1 - 3.3e-24 85.8 0.5 1.5e-23 83.6 0.5 1.8 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 PXF44927.1 - 0.00017 20.9 1.3 0.0012 18.1 1.2 2.0 1 1 0 1 1 1 1 BlaR1 peptidase M56 ApbA_C PF08546.11 PXF44928.1 - 8.2e-27 93.9 0.2 1.2e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 PXF44928.1 - 4.7e-18 65.3 0.8 1.1e-17 64.0 0.8 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PXF44928.1 - 0.00025 21.6 1.0 0.00049 20.6 0.3 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 PXF44928.1 - 0.0024 17.5 0.1 0.054 13.1 0.3 2.2 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PXF44928.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 PXF44928.1 - 0.026 14.4 0.9 0.075 12.9 0.9 1.7 1 1 0 1 1 1 0 Rossmann-like domain NAD_binding_8 PF13450.6 PXF44928.1 - 0.041 14.1 0.6 0.081 13.2 0.6 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PXF44928.1 - 0.076 13.6 0.2 0.19 12.3 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SPG48 PF14764.6 PXF44928.1 - 0.22 12.0 0.1 26 5.3 0.0 2.3 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF1499 PF07386.11 PXF44931.1 - 7.2e-32 110.4 0.0 1.1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) YfiO PF13525.6 PXF44931.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein Glyco_hydr_30_2 PF14587.6 PXF44931.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 YqeY PF09424.10 PXF44932.1 - 1.7e-34 118.9 3.9 2.2e-34 118.6 3.9 1.2 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 PXF44932.1 - 0.014 15.3 0.8 0.037 13.9 0.8 1.8 1 1 0 1 1 1 0 GatB domain Vir_act_alpha_C PF10400.9 PXF44932.1 - 1.1 9.9 5.5 1.8 9.3 2.3 2.7 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF4033 PF13225.6 PXF44934.1 - 4.4e-29 100.3 0.8 4.4e-29 100.3 0.8 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4033) Prok-E2_E PF14462.6 PXF44934.1 - 0.032 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E Abhydrolase_6 PF12697.7 PXF44936.1 - 5.7e-14 53.3 0.2 7.2e-14 52.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF44936.1 - 5.9e-08 32.7 0.0 7.9e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF44936.1 - 6.9e-05 22.2 0.1 0.00021 20.6 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PXF44936.1 - 0.0011 17.8 0.0 0.25 10.0 0.0 2.8 3 0 0 3 3 3 2 Ndr family zf-ribbon_3 PF13248.6 PXF44937.1 - 0.15 11.5 1.7 0.32 10.5 1.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain NHL PF01436.21 PXF44938.1 - 0.047 13.8 0.6 6.1 7.1 0.0 3.9 4 0 0 4 4 4 0 NHL repeat SGL PF08450.12 PXF44938.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Cpn10 PF00166.21 PXF44939.1 - 1.7e-51 172.2 0.2 5.9e-26 90.4 0.0 2.0 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit tRNA_bind PF01588.20 PXF44940.1 - 5.1e-34 116.3 0.1 9e-34 115.5 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain fn3 PF00041.21 PXF44940.1 - 2.2e-05 24.7 0.0 5.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PXF44940.1 - 0.042 14.4 0.0 0.088 13.4 0.0 1.6 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain SPC25 PF06703.11 PXF44941.1 - 0.31 10.8 1.7 0.53 10.0 0.3 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Halogen_Hydrol PF10112.9 PXF44942.1 - 4.3 7.3 9.9 46 4.0 9.9 2.5 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pkinase PF00069.25 PXF44943.1 - 6.5e-61 206.0 0.0 1.5e-60 204.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44943.1 - 6.7e-34 117.3 0.0 9.3e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF44943.1 - 3.2e-06 26.3 0.0 4.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF44943.1 - 5.8e-05 22.5 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF44943.1 - 0.00035 20.0 0.5 0.0019 17.6 0.1 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF44943.1 - 0.00069 19.6 3.6 0.0025 17.8 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 PXF44943.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CmcI PF04989.12 PXF44943.1 - 0.17 11.6 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Chorein_N PF12624.7 PXF44944.1 - 7.2e-17 61.6 0.9 2.5e-16 59.8 0.0 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 YCII PF03795.14 PXF44944.1 - 0.23 11.9 2.7 20 5.7 0.0 3.3 3 0 0 3 3 3 0 YCII-related domain Thioesterase PF00975.20 PXF44944.1 - 0.33 11.0 9.6 0.057 13.5 4.3 2.3 1 1 1 2 2 2 0 Thioesterase domain GAS PF13851.6 PXF44944.1 - 0.36 10.1 19.1 0.86 8.9 19.1 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 PXF44944.1 - 0.9 9.7 9.1 1.2 9.3 7.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 PXF44944.1 - 9.5 4.6 5.4 18 3.7 5.4 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-ANAPC11 PF12861.7 PXF44945.1 - 2.5e-37 126.8 11.2 2.8e-37 126.7 11.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PXF44945.1 - 1.2e-21 76.7 15.7 1.5e-21 76.4 15.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PXF44945.1 - 4e-06 27.1 18.0 4.1e-05 23.8 18.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 PXF44945.1 - 0.00082 19.5 2.1 0.00082 19.5 2.1 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PXF44945.1 - 0.0084 16.0 17.1 0.067 13.1 17.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2310 PF10071.9 PXF44945.1 - 0.073 12.3 1.5 0.11 11.8 1.5 1.4 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Cu-oxidase_2 PF07731.14 PXF44945.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Multicopper oxidase zf-RING_5 PF14634.6 PXF44945.1 - 0.15 12.0 18.6 1.4 8.9 18.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 PXF44945.1 - 0.33 11.3 12.8 0.91 9.9 12.8 1.8 1 1 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.14 PXF44945.1 - 1.2 9.0 5.3 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.6 PXF44945.1 - 1.2 9.0 16.4 71 3.4 16.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PXF44945.1 - 1.3 9.3 15.1 4.4 7.5 15.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Pellino PF04710.14 PXF44945.1 - 5.7 5.5 7.9 1.2 7.8 4.6 1.4 1 1 1 2 2 2 0 Pellino zf-RING_11 PF17123.5 PXF44945.1 - 7.2 6.5 14.3 1e+02 2.8 14.3 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 PXF44945.1 - 7.5 6.4 19.2 0.13 12.0 4.5 2.9 1 1 1 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 PXF44945.1 - 7.7 6.5 21.5 0.21 11.5 12.0 2.7 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) DnaJ-X PF14308.6 PXF44946.1 - 3.2e-31 108.4 0.4 6.3e-28 97.7 0.1 2.5 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 PXF44946.1 - 4.6e-24 84.3 0.4 1.1e-23 83.2 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 PXF44946.1 - 2.3e-11 42.9 14.5 0.00032 20.6 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 PXF44946.1 - 2.9e-10 39.5 8.1 0.026 14.3 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF44946.1 - 3.7e-06 26.7 1.2 0.19 12.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF44946.1 - 2.3e-05 24.0 3.3 0.025 14.2 0.0 4.4 6 0 0 6 6 6 2 TPR repeat TPR_17 PF13431.6 PXF44946.1 - 3.9e-05 23.7 0.0 0.93 10.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF44946.1 - 0.00011 22.7 12.7 2.1 9.4 0.0 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PXF44946.1 - 0.00076 19.6 8.1 2 8.6 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 PXF44946.1 - 0.0059 16.6 1.1 0.41 10.8 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF44946.1 - 0.022 15.4 6.4 6.5 7.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF44946.1 - 0.032 13.6 1.9 0.064 12.6 1.9 1.5 1 0 0 1 1 1 0 MalT-like TPR region TPR_12 PF13424.6 PXF44946.1 - 0.12 12.6 12.7 4.8 7.5 0.2 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF44946.1 - 0.24 11.9 5.0 22 5.7 0.0 4.1 3 1 0 4 4 4 0 Tetratricopeptide repeat HTH_psq PF05225.16 PXF44948.1 - 0.027 14.2 0.2 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 PXF44948.1 - 0.036 14.1 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Apo-VLDL-II PF05418.11 PXF44949.1 - 0.048 14.2 0.0 0.064 13.8 0.0 1.1 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) Band_7 PF01145.25 PXF44950.1 - 0.00092 19.3 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Lactamase_B PF00753.27 PXF44951.1 - 0.023 14.7 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF44951.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ArgoL1 PF08699.10 PXF44953.1 - 1.8e-12 46.8 0.3 3.6e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PXF44953.1 - 2.9e-10 40.9 0.0 4.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 PXF44953.1 - 2.5e-09 37.0 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 PXF44954.1 - 2.5e-84 283.1 0.0 3.5e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 PXF44954.1 - 4.1e-07 30.2 0.0 8.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 PXF44954.1 - 2.2e-06 27.8 0.0 9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute H_PPase PF03030.16 PXF44955.1 - 3.7e-16 58.9 7.3 3.7e-16 58.9 7.3 1.6 2 0 0 2 2 2 1 Inorganic H+ pyrophosphatase Lactamase_B PF00753.27 PXF44958.1 - 1.8e-15 57.5 0.1 2.8e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PXF44958.1 - 5.6e-05 22.8 0.1 9.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aldolase PF01081.19 PXF44958.1 - 0.23 10.8 0.0 0.6 9.5 0.0 1.6 2 0 0 2 2 2 0 KDPG and KHG aldolase FAD_binding_8 PF08022.12 PXF44959.1 - 6.3e-19 68.1 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PXF44959.1 - 3.7e-16 59.6 0.6 4.5e-08 33.4 0.0 3.5 2 2 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF44959.1 - 3e-09 37.0 14.7 3e-09 37.0 14.7 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 PXF44959.1 - 0.0013 19.3 0.0 0.68 10.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF3375 PF11855.8 PXF44959.1 - 0.015 14.2 0.1 0.022 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF3974 PF13120.6 PXF44961.1 - 0.05 13.7 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) VWD PF00094.25 PXF44962.1 - 9.9e-08 32.4 0.0 3.7e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type D domain RGM_N PF06535.12 PXF44962.1 - 0.0019 18.4 0.2 0.0044 17.2 0.2 1.5 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus Glycos_transf_2 PF00535.26 PXF44963.1 - 1.1e-23 83.9 0.0 2.4e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF44963.1 - 9.4e-21 74.8 0.0 1.8e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 PXF44963.1 - 2.2e-15 56.2 0.6 4.5e-10 38.7 1.6 3.2 2 1 1 3 3 3 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 PXF44963.1 - 3.1e-13 50.1 0.9 3.1e-13 50.1 0.9 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 PXF44963.1 - 4.4e-09 36.1 0.0 0.00052 19.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 PXF44963.1 - 0.037 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Methyltransf_11 PF08241.12 PXF44964.1 - 1.4e-09 38.5 0.0 1.9e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF44964.1 - 1.3e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PXF44964.1 - 2.5e-07 31.3 0.0 5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF44964.1 - 0.037 13.8 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.12 PXF44964.1 - 0.088 12.3 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase cobW PF02492.19 PXF44965.1 - 2.9e-07 30.3 0.0 3e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_11 PF08241.12 PXF44969.1 - 0.045 14.4 0.0 0.1 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 PXF44969.1 - 0.067 13.9 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 PXF44970.1 - 3.2e-15 56.5 0.6 7.2e-15 55.3 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PXF44970.1 - 5e-15 55.4 1.0 1.5e-08 34.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PXF44970.1 - 1.2e-12 48.1 0.4 6.8e-06 26.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF44970.1 - 9.1e-10 37.9 0.1 0.0012 19.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PXF44970.1 - 1.7e-06 28.2 0.8 0.033 14.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF4926 PF16277.5 PXF44970.1 - 0.062 12.7 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) Methyltransf_2 PF00891.18 PXF44971.1 - 2.3e-29 102.2 0.0 2.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 PXF44971.1 - 1.5e-16 60.1 0.0 3.7e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain MTS PF05175.14 PXF44971.1 - 5.1e-06 26.1 0.0 8.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PXF44971.1 - 6.9e-06 26.7 0.0 1.7e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF44971.1 - 2.4e-05 24.9 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF44971.1 - 2.8e-05 24.7 0.0 5.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 PXF44971.1 - 6.3e-05 22.9 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 PXF44971.1 - 0.00026 20.9 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF44971.1 - 0.00039 20.2 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MarR_2 PF12802.7 PXF44971.1 - 0.0044 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 PXF44971.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_5 PF01022.20 PXF44971.1 - 0.037 13.9 0.1 0.2 11.5 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 PXF44971.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 PXF44971.1 - 0.095 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DprA_WH PF17782.1 PXF44971.1 - 0.13 12.4 0.3 0.36 11.0 0.3 1.7 1 0 0 1 1 1 0 DprA winged helix domain MarR PF01047.22 PXF44971.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family ResIII PF04851.15 PXF44972.1 - 0.0054 16.7 0.0 0.0058 16.6 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF44972.1 - 0.079 12.7 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ubie_methyltran PF01209.18 PXF44972.1 - 0.083 12.2 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1963 PF09234.10 PXF44975.1 - 3.7e-06 27.6 0.0 7.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) DUF1963 PF09234.10 PXF44981.1 - 0.0059 17.1 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) Bestrophin PF01062.21 PXF44983.1 - 2.8e-86 289.6 20.2 3.2e-20 72.7 0.1 5.4 5 1 0 5 5 5 5 Bestrophin, RFP-TM, chloride channel tRNA-synt_1 PF00133.22 PXF44985.1 - 2.8e-36 125.0 0.0 3.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF44985.1 - 0.0002 20.3 0.0 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 PXF44985.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 PXF44985.1 - 0.21 10.9 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain HTH_11 PF08279.12 PXF44986.1 - 0.0037 17.2 0.3 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 HTH domain RNase_H_2 PF13482.6 PXF44986.1 - 0.18 11.8 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 RNase_H superfamily Glyoxalase PF00903.25 PXF44987.1 - 2.9e-06 27.5 0.0 7.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF44987.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF44987.1 - 0.15 12.9 0.0 0.48 11.2 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain Peroxin-22 PF12827.7 PXF44988.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family DAHP_synth_1 PF00793.20 PXF44990.1 - 0.04 12.8 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family DDE_Tnp_1_7 PF13843.6 PXF44990.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 VWA PF00092.28 PXF44992.1 - 9.6e-14 52.0 0.0 1.3e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44992.1 - 7.4e-07 29.8 0.0 1.8e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF44992.1 - 0.023 13.9 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) ELYS PF13934.6 PXF44992.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly VWA PF00092.28 PXF44993.1 - 2.3e-07 31.2 0.0 3.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF44993.1 - 0.0016 19.0 0.0 0.0032 18.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PXF44993.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 PXF44993.1 - 0.0045 16.2 0.0 0.98 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) WXG100 PF06013.12 PXF44994.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF44994.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF44994.1 - 0.41 11.4 5.2 0.8 10.4 5.2 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Pyridoxal_deC PF00282.19 PXF44995.1 - 8.6e-18 64.2 0.0 1.5e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain OAD_gamma PF04277.13 PXF44996.1 - 0.65 10.6 11.2 0.34 11.5 5.4 2.4 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Bromodomain PF00439.25 PXF44997.1 - 0.00042 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain F-box-like PF12937.7 PXF44998.1 - 0.0015 18.4 0.0 0.0077 16.1 0.0 2.3 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.25 PXF44999.1 - 1.5e-61 208.1 0.0 1.8e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF44999.1 - 3.2e-33 115.1 0.0 1.1e-32 113.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF44999.1 - 4.2e-07 29.5 0.1 6.1e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF44999.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF44999.1 - 0.0093 14.9 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF4729 PF15866.5 PXF44999.1 - 0.021 14.2 0.7 0.034 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF44999.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PXF44999.1 - 0.031 14.2 0.1 0.17 11.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Bromodomain PF00439.25 PXF45000.1 - 7.5e-13 48.4 0.2 1e-12 47.9 0.2 1.2 1 0 0 1 1 1 1 Bromodomain F-box-like PF12937.7 PXF45001.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 PXF45002.1 - 2.3e-61 207.5 0.0 2.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45002.1 - 2.4e-33 115.5 0.0 8e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF45002.1 - 4e-07 29.6 0.1 5.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF45002.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF45002.1 - 0.015 14.3 0.2 0.018 14.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF45002.1 - 0.021 14.2 0.7 0.034 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF45002.1 - 0.025 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PXF45002.1 - 0.031 14.2 0.1 0.17 11.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Bromodomain PF00439.25 PXF45003.1 - 0.00042 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 PXF45005.1 - 7.7e-37 127.1 0.0 8.6e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45005.1 - 5.9e-23 81.5 0.0 6.8e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF45005.1 - 1.3e-05 24.7 0.1 1.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF45005.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF45005.1 - 0.0056 15.7 0.1 0.0062 15.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PXF45005.1 - 0.0059 15.4 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF45005.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Bromodomain PF00439.25 PXF45006.1 - 0.00042 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain F-box-like PF12937.7 PXF45007.1 - 0.003 17.4 1.6 0.0088 15.9 0.0 2.7 2 1 0 2 2 2 1 F-box-like Pkinase PF00069.25 PXF45008.1 - 2.3e-61 207.5 0.0 2.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45008.1 - 2.4e-33 115.5 0.0 8e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF45008.1 - 4e-07 29.6 0.1 5.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF45008.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF45008.1 - 0.015 14.3 0.2 0.018 14.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF45008.1 - 0.021 14.2 0.7 0.034 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF45008.1 - 0.025 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PXF45008.1 - 0.031 14.2 0.1 0.17 11.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Bromodomain PF00439.25 PXF45009.1 - 0.00042 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain F-box-like PF12937.7 PXF45010.1 - 0.0015 18.4 0.0 0.0077 16.1 0.0 2.3 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.25 PXF45011.1 - 2.3e-61 207.5 0.0 2.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45011.1 - 2.4e-33 115.5 0.0 8e-33 113.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF45011.1 - 4e-07 29.6 0.1 5.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF45011.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF45011.1 - 0.015 14.3 0.2 0.018 14.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF45011.1 - 0.021 14.2 0.7 0.034 13.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF45011.1 - 0.025 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PXF45011.1 - 0.031 14.2 0.1 0.17 11.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC_ATPase PF09818.9 PXF45012.1 - 1.2e-21 77.1 0.0 1.3e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class TrbC PF04956.13 PXF45014.1 - 0.05 13.8 0.1 0.05 13.8 0.1 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family AAA PF00004.29 PXF45016.1 - 1.1e-17 64.7 0.0 3.1e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 PXF45016.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF45016.1 - 0.035 14.5 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 PXF45016.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PXF45016.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC CitT PF12431.8 PXF45016.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator NTP_transferase PF00483.23 PXF45018.1 - 2.6e-15 56.7 0.0 4.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 PXF45018.1 - 4.7e-08 33.6 0.0 7.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 PXF45018.1 - 1.5e-06 27.7 8.0 0.007 16.1 0.8 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 PXF45018.1 - 0.016 13.4 0.9 0.023 12.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PXF45018.1 - 0.64 8.9 2.7 2.2 7.2 2.7 1.8 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 PXF45018.1 - 1 9.2 9.0 9.7 6.1 2.2 3.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Hint PF01079.20 PXF45019.1 - 7e-23 81.3 0.0 1.8e-22 79.9 0.0 1.6 1 1 0 1 1 1 1 Hint module Fasciclin PF02469.22 PXF45019.1 - 3.5e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain Hint PF01079.20 PXF45020.1 - 1.4e-28 99.9 0.0 3.5e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Hint module Fasciclin PF02469.22 PXF45020.1 - 4.6e-08 33.3 0.0 2.3e-06 27.8 0.0 2.5 1 1 0 1 1 1 1 Fasciclin domain Vint PF14623.6 PXF45020.1 - 0.039 13.8 0.0 1.2 8.9 0.0 2.4 1 1 0 2 2 2 0 Hint-domain PT-HINT PF07591.11 PXF45020.1 - 0.19 12.0 0.0 0.7 10.1 0.0 1.8 2 0 0 2 2 2 0 Pretoxin HINT domain WD40 PF00400.32 PXF45022.1 - 1.4e-46 155.5 19.9 5.2e-08 33.4 0.3 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat NB-ARC PF00931.22 PXF45022.1 - 3.7e-15 55.8 0.1 8.2e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF45022.1 - 1.2e-12 48.0 4.2 0.13 12.6 0.1 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain DUF727 PF05303.12 PXF45022.1 - 0.00053 20.0 0.3 30 4.7 0.0 4.5 2 1 1 4 4 4 0 Protein of unknown function (DUF727) Jnk-SapK_ap_N PF09744.9 PXF45022.1 - 0.0033 17.7 1.3 0.0082 16.4 1.3 1.7 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ChapFlgA PF13144.6 PXF45022.1 - 0.0037 17.3 2.7 25 4.9 0.1 4.8 2 1 2 5 5 5 0 Chaperone for flagella basal body P-ring formation AAA_22 PF13401.6 PXF45022.1 - 0.006 16.9 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.8 PXF45022.1 - 0.011 14.4 5.5 4.4 5.8 0.1 4.7 5 0 0 5 5 5 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PXF45022.1 - 0.018 14.0 2.5 9.4 5.1 0.0 4.6 1 1 5 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 PXF45022.1 - 0.051 11.6 0.0 0.11 10.4 0.0 1.5 1 0 0 1 1 1 0 IKI3 family Me-amine-dh_H PF06433.11 PXF45022.1 - 0.051 12.4 0.0 13 4.6 0.0 3.0 1 1 3 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) APAF1_C PF17908.1 PXF45022.1 - 0.14 12.2 1.7 0.21 11.6 0.1 2.2 3 0 0 3 3 3 0 APAF-1 helical domain PQQ_3 PF13570.6 PXF45022.1 - 0.55 10.8 8.9 26 5.5 0.0 5.4 5 1 1 6 6 6 0 PQQ-like domain WD40 PF00400.32 PXF45024.1 - 3.8e-43 144.6 22.2 1.7e-08 35.0 0.6 7.2 7 0 0 7 7 6 5 WD domain, G-beta repeat NB-ARC PF00931.22 PXF45024.1 - 1.8e-13 50.3 0.0 3.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ANAPC4_WD40 PF12894.7 PXF45024.1 - 3.4e-09 36.9 7.9 0.071 13.4 0.1 6.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain ChapFlgA PF13144.6 PXF45024.1 - 7.2e-05 22.8 4.3 4.2 7.4 0.0 5.0 3 1 2 5 5 5 2 Chaperone for flagella basal body P-ring formation Jnk-SapK_ap_N PF09744.9 PXF45024.1 - 0.0031 17.8 1.3 0.0085 16.3 1.3 1.7 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Ge1_WD40 PF16529.5 PXF45024.1 - 0.006 15.6 3.9 6.3 5.7 0.0 5.4 1 1 6 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 PXF45024.1 - 0.0068 16.7 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF727 PF05303.12 PXF45024.1 - 0.016 15.3 0.2 75 3.5 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF727) BBS2_Mid PF14783.6 PXF45024.1 - 0.02 15.0 0.0 9.6 6.3 0.0 4.4 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 PXF45024.1 - 0.039 12.6 11.0 7.1 5.1 0.0 5.3 4 2 2 6 6 6 0 Nucleoporin Nup120/160 IKI3 PF04762.12 PXF45024.1 - 0.075 11.0 0.0 0.18 9.8 0.0 1.6 1 0 0 1 1 1 0 IKI3 family WD40 PF00400.32 PXF45025.1 - 3.5e-79 258.7 45.1 2e-08 34.7 0.6 11.0 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45025.1 - 6.9e-15 55.1 18.1 0.11 12.8 0.1 9.8 1 1 9 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF45025.1 - 1.2e-13 50.9 0.0 2.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ChapFlgA PF13144.6 PXF45025.1 - 8.2e-11 42.0 13.6 6.7 6.8 0.0 8.8 7 2 2 9 9 9 5 Chaperone for flagella basal body P-ring formation DUF727 PF05303.12 PXF45025.1 - 3.1e-06 27.2 2.5 88 3.2 0.0 7.7 8 0 0 8 8 8 0 Protein of unknown function (DUF727) PD40 PF07676.12 PXF45025.1 - 7e-06 25.8 0.0 1.9e+02 2.1 0.0 8.8 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 PXF45025.1 - 0.00014 21.0 9.5 14 4.5 0.1 8.2 1 1 10 11 11 11 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 PXF45025.1 - 0.00076 19.5 0.2 11 6.1 0.0 6.5 10 0 0 10 10 9 1 Ciliary BBSome complex subunit 2, middle region Jnk-SapK_ap_N PF09744.9 PXF45025.1 - 0.0039 17.4 1.3 0.01 16.1 1.3 1.7 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 AAA_22 PF13401.6 PXF45025.1 - 0.0087 16.3 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain IKI3 PF04762.12 PXF45025.1 - 0.092 10.7 0.0 0.21 9.5 0.0 1.6 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.6 PXF45025.1 - 0.15 12.5 15.6 68 4.1 0.0 8.1 5 3 5 10 10 8 0 PQQ-like domain Nup160 PF11715.8 PXF45025.1 - 7 5.2 27.2 8.3 4.9 0.0 8.1 8 2 2 10 10 10 0 Nucleoporin Nup120/160 NAM-associated PF14303.6 PXF45026.1 - 1.9e-06 28.7 0.6 2.5e-06 28.3 0.6 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Frag1 PF10277.9 PXF45027.1 - 0.0051 16.4 0.0 0.0056 16.2 0.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MCM_lid PF17855.1 PXF45028.1 - 0.065 13.7 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 MCM AAA-lid domain WD40 PF00400.32 PXF45032.1 - 2.6e-19 69.2 13.2 5.2e-05 23.9 0.1 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat PRP4 PF08799.11 PXF45032.1 - 2.7e-13 49.2 1.6 6e-13 48.1 1.6 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 PXF45032.1 - 5.5e-06 26.6 0.0 0.0063 16.8 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FtsJ PF01728.19 PXF45033.1 - 2.9e-25 89.4 0.0 3.5e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2730 PF10805.8 PXF45034.1 - 0.065 13.3 0.5 0.2 11.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Far-17a_AIG1 PF04750.14 PXF45035.1 - 1.3e-10 41.0 1.1 1.4e-10 40.8 1.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SUIM_assoc PF16619.5 PXF45036.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NB-ARC PF00931.22 PXF45037.1 - 9.2e-17 61.1 0.0 1.9e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain WD40 PF00400.32 PXF45037.1 - 8.9e-13 48.5 9.7 0.002 18.9 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45037.1 - 9.7e-13 48.2 4.1 0.016 15.5 0.0 5.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain APAF1_C PF17908.1 PXF45037.1 - 0.0013 18.7 0.0 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 APAF-1 helical domain FlaC_arch PF05377.11 PXF45037.1 - 0.19 12.2 0.1 6.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Hira PF07569.11 PXF45037.1 - 0.27 10.9 3.1 2.5 7.8 0.0 3.9 5 1 1 6 6 6 0 TUP1-like enhancer of split CCDC-167 PF15188.6 PXF45037.1 - 1.2 9.6 9.1 0.51 10.7 0.1 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DnaJ PF00226.31 PXF45038.1 - 5e-15 55.4 0.1 2e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain HEAT_2 PF13646.6 PXF45038.1 - 9.5e-08 32.3 1.3 0.00023 21.5 0.3 3.2 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 PXF45038.1 - 3.3e-05 23.8 3.8 0.47 10.9 0.1 4.4 3 0 0 3 3 3 2 HEAT repeat HEAT_PBS PF03130.16 PXF45038.1 - 0.00054 20.4 13.5 5.8 7.9 0.0 5.3 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 PXF45038.1 - 0.029 12.9 0.0 0.13 10.8 0.0 1.9 1 1 0 1 1 1 0 Adaptin N terminal region DEK_C PF08766.11 PXF45038.1 - 0.034 14.1 2.0 0.061 13.2 0.1 2.4 3 0 0 3 3 3 0 DEK C terminal domain HEAT_EZ PF13513.6 PXF45038.1 - 0.038 14.5 7.2 0.38 11.3 3.7 3.3 3 0 0 3 3 3 0 HEAT-like repeat VPR PF00522.18 PXF45038.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 VPR/VPX protein PEP-utilisers_N PF05524.13 PXF45038.1 - 0.091 12.9 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Vac14_Fab1_bd PF12755.7 PXF45038.1 - 0.15 12.6 0.1 92 3.7 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RabGAP-TBC PF00566.18 PXF45039.1 - 1.3e-34 119.7 0.0 2.1e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 PXF45039.1 - 2.9e-05 24.5 0.0 5.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF3880 PF12996.7 PXF45039.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Bin3 PF06859.12 PXF45040.1 - 7.4e-31 107.0 0.0 1.2e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 PXF45040.1 - 4.4e-11 43.4 0.0 2.4e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF45040.1 - 6.3e-11 42.4 0.0 9.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF45040.1 - 1.2e-09 38.7 0.1 1.4e-08 35.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF45040.1 - 7.7e-09 36.1 0.0 3.1e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF45040.1 - 2.9e-08 33.6 0.0 4.4e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PXF45040.1 - 0.0004 20.3 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 PXF45040.1 - 0.00082 18.8 0.0 0.0053 16.2 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_4 PF02390.17 PXF45040.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 PXF45040.1 - 0.076 12.6 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain MetW PF07021.12 PXF45040.1 - 0.097 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HSP70 PF00012.20 PXF45041.1 - 4.7e-272 903.6 6.5 5.5e-272 903.3 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PXF45041.1 - 3.2e-16 59.1 0.6 4.2e-13 48.8 0.1 2.7 2 1 0 2 2 2 2 MreB/Mbl protein DUF16 PF01519.16 PXF45041.1 - 0.013 16.0 0.1 0.036 14.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 FtsA PF14450.6 PXF45041.1 - 0.047 14.1 5.6 4.3 7.8 0.0 3.8 3 2 0 3 3 3 0 Cell division protein FtsA SKA1 PF07160.12 PXF45041.1 - 0.39 10.5 7.0 0.19 11.5 4.5 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MBOAT PF03062.19 PXF45042.1 - 1.9e-45 155.8 12.4 1.9e-45 155.8 12.4 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Rsc14 PF08586.10 PXF45043.1 - 0.14 12.9 0.2 0.14 12.9 0.2 1.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DDE_Tnp_4 PF13359.6 PXF45044.1 - 2.8e-10 40.1 0.0 3.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 PXF45047.1 - 3.2e-10 39.9 0.0 4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 PXF45050.1 - 1.5e-17 63.1 27.0 2.2e-07 31.0 0.1 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PXF45050.1 - 2.2e-16 59.3 35.4 0.0018 18.6 2.4 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF45050.1 - 1.1e-12 47.7 34.8 0.0049 17.6 2.4 5.7 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF45050.1 - 1.9e-06 28.6 15.1 0.048 14.3 0.5 4.0 1 1 3 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 PXF45050.1 - 2.3e-05 24.5 14.3 0.62 10.4 0.1 5.4 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF45050.1 - 3.1e-05 24.2 19.0 1.5 9.4 0.1 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 PXF45050.1 - 4.7e-05 23.6 16.4 0.00094 19.4 2.2 3.5 1 1 2 3 3 3 2 C2H2-type zinc ribbon RNA_POL_M_15KD PF02150.16 PXF45050.1 - 0.015 15.2 7.6 0.12 12.3 0.0 3.9 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit zf-C2HE PF16278.5 PXF45050.1 - 0.017 15.6 15.6 5.1 7.6 0.2 4.5 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 PXF45050.1 - 0.045 13.8 0.6 0.045 13.8 0.6 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-AN1 PF01428.16 PXF45050.1 - 0.079 13.1 14.5 3.3 8.0 0.1 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger ATPase-cat_bd PF12156.8 PXF45050.1 - 0.079 13.7 1.7 0.079 13.7 1.7 3.0 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase HNH_5 PF14279.6 PXF45050.1 - 0.18 11.7 9.1 1.2 9.0 2.1 4.1 3 1 1 4 4 4 0 HNH endonuclease zf-C2H2_2 PF12756.7 PXF45050.1 - 0.19 12.1 20.4 2.1 8.7 0.3 4.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 PXF45050.1 - 0.22 11.7 16.3 1.1 9.4 0.7 3.7 3 1 0 3 3 3 0 Zinc ribbon domain HypA PF01155.19 PXF45050.1 - 0.24 11.4 8.9 0.7 9.9 1.3 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 PXF45050.1 - 0.35 10.7 0.2 0.35 10.7 0.2 4.3 5 0 0 5 5 5 0 HypF finger Actin_micro PF17003.5 PXF45050.1 - 0.36 9.9 18.7 3.9 6.5 1.1 3.8 1 1 2 3 3 3 0 Putative actin-like family FdhD-NarQ PF02634.15 PXF45050.1 - 1.7 8.3 4.3 0.76 9.4 0.5 1.9 1 1 1 2 2 2 0 FdhD/NarQ family zf-CHCC PF10276.9 PXF45050.1 - 2.1 8.5 10.6 19 5.4 0.2 4.5 5 0 0 5 5 5 0 Zinc-finger domain LIM PF00412.22 PXF45050.1 - 2.5 8.4 14.0 23 5.3 2.7 3.9 1 1 3 4 4 4 0 LIM domain zf-ISL3 PF14690.6 PXF45050.1 - 2.8 8.7 20.9 0.19 12.4 1.5 4.5 4 1 1 5 5 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-H2C2_5 PF13909.6 PXF45050.1 - 3 7.7 27.3 0.17 11.7 0.6 5.5 5 1 0 5 5 5 0 C2H2-type zinc-finger domain ADK_lid PF05191.14 PXF45050.1 - 3.5 7.7 11.4 3.2 7.8 1.4 4.1 3 2 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_9 PF14369.6 PXF45050.1 - 5.4 7.4 12.8 8.2 6.8 0.1 4.7 5 1 0 5 5 5 0 zinc-ribbon zinc-ribbons_6 PF07191.12 PXF45050.1 - 8.3 6.5 12.2 29 4.7 2.2 3.7 1 1 2 3 3 3 0 zinc-ribbons VCBS PF13517.6 PXF45051.1 - 5.9e-23 81.2 21.8 2.4e-09 37.7 4.2 5.2 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF45051.1 - 6.3e-07 29.4 29.4 0.096 12.8 0.1 5.8 6 0 0 6 6 6 5 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF45051.1 - 8e-06 25.7 0.2 1.5e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 ASPIC and UnbV VCBS PF13517.6 PXF45052.1 - 2.6e-21 76.0 25.0 2.6e-09 37.5 8.6 6.0 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 PXF45052.1 - 8.9e-06 25.6 0.3 2e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 PXF45052.1 - 7.2e-05 22.8 27.8 0.041 14.0 0.3 5.0 5 0 0 5 5 5 4 FG-GAP repeat VWA PF00092.28 PXF45058.1 - 3.9e-09 37.0 0.0 4.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF45058.1 - 4.1e-05 24.2 0.0 0.0001 22.9 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PXF45059.1 - 2.6e-16 60.4 0.0 3.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF45059.1 - 8.6e-06 26.4 0.0 1.7e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF45059.1 - 0.00057 19.2 0.0 0.0036 16.6 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) DUF1666 PF07891.12 PXF45064.1 - 0.018 14.7 1.9 0.02 14.6 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) SNARE_assoc PF09335.11 PXF45066.1 - 6.1e-24 84.8 5.1 6.1e-24 84.8 5.1 2.5 2 1 1 3 3 3 2 SNARE associated Golgi protein Clostridium_P47 PF06597.11 PXF45067.1 - 3.1e-54 184.5 20.3 6.1e-47 160.4 13.7 2.1 1 1 0 2 2 2 2 Clostridium P-47 protein DUF3712 PF12505.8 PXF45067.1 - 0.059 13.6 4.7 0.46 10.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3712) Clostridium_P47 PF06597.11 PXF45068.1 - 3.1e-39 135.0 0.2 4.2e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 Clostridium P-47 protein Clostridium_P47 PF06597.11 PXF45069.1 - 4.5e-102 342.2 0.7 5.1e-102 342.0 0.7 1.0 1 0 0 1 1 1 1 Clostridium P-47 protein DUF4781 PF16013.5 PXF45069.1 - 0.14 11.0 0.5 0.23 10.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Methyltransf_11 PF08241.12 PXF45070.1 - 1.6e-14 54.3 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF45070.1 - 3e-11 43.9 0.0 7.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF45070.1 - 2.3e-07 30.4 0.0 4.8e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF45070.1 - 1.2e-06 28.4 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45070.1 - 2.5e-06 28.1 0.0 5.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CpeT PF06206.11 PXF45073.1 - 2.9e-13 50.2 0.0 5.6e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 CpeT/CpcT family (DUF1001) NAM-associated PF14303.6 PXF45074.1 - 8.3e-06 26.6 2.5 1.3e-05 25.9 2.5 1.4 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain VWA PF00092.28 PXF45078.1 - 3.7e-17 63.1 0.0 4.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF45078.1 - 7.6e-07 29.8 0.0 1.4e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PXF45078.1 - 0.00058 19.1 0.0 0.0044 16.2 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1194) VWA PF00092.28 PXF45079.1 - 2.8e-11 44.0 0.1 3.4e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF45079.1 - 2.2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4551 PF15087.6 PXF45083.1 - 0.61 8.9 4.8 1.3 7.8 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tyrosinase PF00264.20 PXF45083.1 - 3.5 7.8 11.3 3.2 8.0 1.4 2.5 2 0 0 2 2 2 0 Common central domain of tyrosinase DENN PF02141.21 PXF45089.1 - 4.6e-23 82.1 2.2 1.8e-22 80.2 0.4 2.6 3 0 0 3 3 3 1 DENN (AEX-3) domain SPA PF08616.10 PXF45089.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Thioredoxin PF00085.20 PXF45090.1 - 4.8e-26 90.7 0.0 6.3e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF45090.1 - 1.9e-05 24.2 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF45090.1 - 0.0001 22.6 0.0 0.018 15.4 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PXF45090.1 - 0.00011 22.5 0.1 0.00081 19.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF45090.1 - 0.0022 18.2 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 PXF45090.1 - 0.0027 17.5 0.0 0.0038 17.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 PXF45090.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_5 PF13743.6 PXF45090.1 - 0.035 13.8 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 PXF45090.1 - 0.051 13.3 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 Redoxin DUF4290 PF14123.6 PXF45090.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4290) TraF PF13728.6 PXF45090.1 - 0.06 13.2 0.1 0.084 12.7 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein INCENP_ARK-bind PF03941.15 PXF45091.1 - 7.3e-10 38.7 0.4 2.5e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region CTP_synth_N PF06418.14 PXF45093.1 - 4.8e-122 406.4 0.0 8.8e-122 405.5 0.0 1.4 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 PXF45093.1 - 1.7e-29 102.9 0.0 2e-22 79.9 0.0 2.6 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 PXF45093.1 - 0.0057 16.7 0.0 0.0091 16.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.13 PXF45093.1 - 0.056 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 zf-RING_2 PF13639.6 PXF45094.1 - 2.8e-09 37.2 5.3 2.8e-09 37.2 5.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF45094.1 - 9e-09 35.0 4.3 2.4e-08 33.7 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF45094.1 - 1e-07 32.1 6.1 2.5e-07 30.9 6.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF45094.1 - 1.2e-07 31.5 2.4 3.4e-07 30.0 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF45094.1 - 1e-05 25.2 1.9 2.7e-05 23.8 1.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 PXF45094.1 - 4.7e-05 23.1 0.8 0.0001 22.1 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF45094.1 - 0.00025 21.0 4.0 0.0005 20.1 4.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PXF45094.1 - 0.00087 19.3 4.5 0.0024 17.8 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF45094.1 - 0.0011 18.8 1.3 0.0027 17.6 1.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PXF45094.1 - 0.025 14.7 2.2 0.042 14.0 1.0 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 PXF45094.1 - 0.075 12.9 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF45094.1 - 0.16 11.9 5.4 0.25 11.3 2.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PXF45094.1 - 0.37 10.5 5.1 0.43 10.3 3.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PXF45094.1 - 0.48 10.6 4.6 1.6 8.9 4.6 2.0 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PXF45094.1 - 2.8 8.2 7.0 23 5.2 7.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 PXF45094.1 - 3.2 7.6 6.4 1.8 8.5 4.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain bZIP_1 PF00170.21 PXF45096.1 - 0.0069 16.5 15.1 0.0069 16.5 15.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor Nsp1_C PF05064.13 PXF45096.1 - 0.031 14.1 3.2 0.053 13.3 3.2 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region PGA2 PF07543.12 PXF45096.1 - 0.88 9.5 10.5 1.3 9.1 10.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 WDCP PF15390.6 PXF45096.1 - 4.4 5.6 8.1 5.4 5.3 8.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family YebO PF13974.6 PXF45096.1 - 7.6 6.7 8.4 0.89 9.7 2.6 2.2 1 1 1 2 2 2 0 YebO-like protein DDE_1 PF03184.19 PXF45097.1 - 3.3e-31 108.3 0.1 5.5e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1170 PF06663.13 PXF45098.1 - 0.019 14.7 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) NT-C2 PF10358.9 PXF45099.1 - 3.8e-11 42.9 0.2 1.3e-10 41.2 0.2 1.9 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins GAS PF13851.6 PXF45099.1 - 0.0072 15.7 4.9 0.0072 15.7 4.9 6.8 2 2 3 6 6 6 4 Growth-arrest specific micro-tubule binding ADIP PF11559.8 PXF45099.1 - 0.015 15.4 12.0 0.015 15.4 12.0 7.2 2 2 4 7 7 7 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 PXF45099.1 - 0.42 9.4 103.5 0.15 10.9 32.8 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 PXF45099.1 - 0.93 6.9 93.7 0.062 10.8 14.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 PXF45099.1 - 2.1 7.1 91.7 0.057 12.3 25.8 4.3 2 2 0 3 3 3 0 Spc7 kinetochore protein Gelsolin PF00626.22 PXF45100.1 - 2.3e-24 85.1 2.7 4.1e-12 45.8 0.1 3.3 3 0 0 3 3 3 3 Gelsolin repeat DUF617 PF04759.13 PXF45100.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Pkinase PF00069.25 PXF45104.1 - 1.2e-54 185.5 0.0 1.7e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45104.1 - 1.8e-29 102.9 0.0 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF45104.1 - 0.00085 18.2 0.0 0.0017 17.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF45104.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PXF45105.1 - 4.7e-58 196.5 0.0 6e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF45105.1 - 1.2e-47 162.5 0.0 1.8e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PXF45105.1 - 6.5e-05 22.0 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PXF45105.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PXF45105.1 - 0.15 12.0 0.6 0.24 11.3 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATP-synt_C PF00137.21 PXF45106.1 - 8.7e-27 93.2 27.6 2.1e-14 53.6 7.7 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Tyrosinase PF00264.20 PXF45107.1 - 7e-46 157.3 4.3 1.8e-45 155.9 4.3 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase MCM_OB PF17207.3 PXF45109.1 - 4e-05 23.5 0.1 6.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 PXF45109.1 - 5.9e-05 23.6 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain Xan_ur_permease PF00860.20 PXF45109.1 - 0.0013 17.5 0.5 0.0019 17.0 0.5 1.2 1 0 0 1 1 1 1 Permease family Uma2 PF05685.12 PXF45110.1 - 3.8e-25 88.4 0.0 5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Glyco_hydro_16 PF00722.21 PXF45111.1 - 2.8e-13 49.7 0.2 4.3e-13 49.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PTH2 PF01981.16 PXF45112.1 - 4.6e-38 130.1 0.5 5.7e-38 129.8 0.5 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GFO_IDH_MocA PF01408.22 PXF45113.1 - 2e-19 70.6 0.0 3.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Hexapep PF00132.24 PXF45113.1 - 6.2e-19 66.9 10.2 1.4e-05 24.6 2.5 3.9 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PXF45113.1 - 5.4e-14 51.6 9.3 4.1e-06 26.4 2.4 4.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF2613 PF11021.8 PXF45113.1 - 0.32 11.1 4.0 0.98 9.6 4.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Sulfotransfer_2 PF03567.14 PXF45114.1 - 2.6e-09 37.4 0.1 3.3e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family DPBB_1 PF03330.18 PXF45115.1 - 0.0019 18.4 0.1 0.0056 16.9 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase UEV PF05743.13 PXF45116.1 - 3.1e-31 107.8 0.1 5e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 PXF45116.1 - 9.8e-18 63.9 0.2 2.3e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 PXF45116.1 - 9.1e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cullin PF00888.22 PXF45116.1 - 0.00055 18.7 0.3 0.0007 18.3 0.3 1.1 1 0 0 1 1 1 1 Cullin family Vps5 PF09325.10 PXF45116.1 - 0.039 13.5 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like SHOCT PF09851.9 PXF45116.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain Nexin_C PF08628.12 PXF45116.1 - 0.11 13.1 0.1 0.3 11.7 0.1 1.8 1 1 0 1 1 1 0 Sorting nexin C terminal V_ATPase_I PF01496.19 PXF45116.1 - 0.12 10.3 0.8 0.16 9.9 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AhpC-TSA PF00578.21 PXF45117.1 - 4.6e-29 100.9 0.0 5.9e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF45117.1 - 2.2e-19 69.6 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 PXF45117.1 - 0.025 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) MMR_HSR1 PF01926.23 PXF45118.1 - 2.8e-10 40.3 0.0 0.00024 21.2 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF45118.1 - 0.00016 21.6 1.1 0.14 12.0 0.1 3.7 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 PXF45118.1 - 0.00088 18.9 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 PXF45118.1 - 0.00095 18.8 0.4 0.0071 16.0 0.0 2.5 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 PXF45118.1 - 0.0038 16.8 0.1 2 8.0 0.0 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B MeaB PF03308.16 PXF45118.1 - 0.0098 14.9 0.1 0.2 10.6 0.0 2.6 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Glyco_hydro_16 PF00722.21 PXF45119.1 - 8.6e-08 31.9 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 PXF45120.1 - 1.9e-17 63.3 0.2 2.7e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L37ae PF01780.19 PXF45120.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family DNA_pol_B PF00136.21 PXF45121.1 - 1.7e-136 455.6 0.1 2.1e-136 455.3 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PXF45121.1 - 2.7e-76 256.9 0.0 4.6e-76 256.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PXF45121.1 - 7e-15 55.2 6.6 1.6e-14 54.1 6.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 PXF45121.1 - 0.02 14.9 0.0 0.096 12.7 0.0 2.2 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_2 PF03175.13 PXF45121.1 - 0.033 13.1 0.3 0.082 11.8 0.2 1.6 1 1 0 1 1 1 0 DNA polymerase type B, organellar and viral Peptidase_S8 PF00082.22 PXF45122.1 - 3.8e-29 101.9 5.9 5.2e-29 101.4 5.9 1.1 1 0 0 1 1 1 1 Subtilase family IFRD_C PF04836.12 PXF45122.1 - 0.25 11.9 0.0 0.25 11.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-related protein conserved region Amidase PF01425.21 PXF45123.1 - 9.9e-160 532.4 0.8 1.1e-159 532.2 0.8 1.0 1 0 0 1 1 1 1 Amidase Arm-DNA-bind_3 PF13356.6 PXF45123.1 - 0.033 14.6 0.7 0.12 12.8 0.1 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Gliadin PF13016.6 PXF45123.1 - 0.18 12.2 0.1 0.32 11.5 0.1 1.3 1 0 0 1 1 1 0 Cys-rich Gliadin N-terminal AAA_lid_6 PF17866.1 PXF45125.1 - 3.1e-14 52.9 1.9 3.9e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 PXF45125.1 - 1.4e-13 51.4 0.0 3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PXF45125.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF45125.1 - 0.00047 20.4 1.6 0.43 10.8 0.1 2.9 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 PXF45125.1 - 0.0021 17.5 0.7 0.025 13.9 0.3 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 PXF45125.1 - 0.0026 17.7 0.2 0.0059 16.5 0.2 1.7 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 PXF45125.1 - 0.0043 17.4 0.3 0.023 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Nsp1_C PF05064.13 PXF45125.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region AAA_19 PF13245.6 PXF45125.1 - 0.0084 16.4 0.1 0.024 15.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PXF45125.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 PXF45125.1 - 0.014 16.0 1.5 0.11 13.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 PXF45125.1 - 0.016 15.3 1.0 0.023 14.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zot PF05707.12 PXF45125.1 - 0.02 14.5 0.1 1.2 8.7 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_28 PF13521.6 PXF45125.1 - 0.03 14.5 0.7 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PXF45125.1 - 0.039 12.9 0.1 0.075 11.9 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 PXF45125.1 - 0.044 13.0 1.3 0.61 9.3 1.3 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 PXF45125.1 - 0.07 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 PXF45125.1 - 0.074 13.0 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Torsin PF06309.11 PXF45125.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Torsin KTI12 PF08433.10 PXF45125.1 - 0.11 12.0 1.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 PXF45125.1 - 0.12 12.1 0.8 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 PXF45125.1 - 0.13 12.3 1.3 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 PXF45125.1 - 0.51 9.3 4.5 0.13 11.3 0.2 2.0 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLTH PF10607.9 PXF45126.1 - 1.5e-10 41.2 0.1 2.3e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PXF45126.1 - 3.4e-05 23.6 0.1 6.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 LisH RRM_1 PF00076.22 PXF45127.1 - 3.9e-28 97.1 0.6 3.9e-15 55.4 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF45127.1 - 3.6e-06 27.0 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif TcpA PF05946.12 PXF45127.1 - 9.1e-05 22.6 0.1 0.00026 21.1 0.0 1.8 2 1 1 3 3 3 1 Toxin-coregulated pilus subunit TcpA RRM_occluded PF16842.5 PXF45127.1 - 9.7e-05 22.2 0.0 0.075 12.9 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif Spo7_2_N PF15407.6 PXF45127.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Sporulation protein family 7 Glyco_transf_22 PF03901.17 PXF45128.1 - 1.8e-46 159.3 23.6 2.2e-46 158.9 23.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L25p PF01386.19 PXF45129.1 - 0.089 13.3 0.2 0.21 12.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L25p family CN_hydrolase PF00795.22 PXF45130.1 - 4.9e-56 190.0 0.0 5.5e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetate_kinase PF00871.17 PXF45130.1 - 0.22 10.2 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family rRNA_methylase PF06962.12 PXF45131.1 - 7.3e-36 123.2 0.0 1.3e-35 122.3 0.0 1.4 2 0 0 2 2 2 1 Putative rRNA methylase Methyltransf_25 PF13649.6 PXF45131.1 - 0.00014 22.5 0.0 0.00029 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF45131.1 - 0.00048 19.5 0.1 0.00067 19.1 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF45131.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pacs-1 PF10254.9 PXF45131.1 - 0.097 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Coatomer_WDAD PF04053.14 PXF45132.1 - 1.7e-108 363.5 0.0 2.6e-108 362.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 PXF45132.1 - 7.7e-83 278.5 0.0 1.8e-82 277.2 0.0 1.6 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 PXF45132.1 - 5.3e-41 137.8 18.7 2.1e-08 34.7 0.4 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45132.1 - 6.5e-09 36.0 1.6 0.0029 17.9 0.0 5.6 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PXF45132.1 - 0.0069 15.1 10.5 0.38 9.3 0.2 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 TPR_19 PF14559.6 PXF45132.1 - 0.0076 16.7 1.9 0.58 10.7 1.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat LisH PF08513.11 PXF45132.1 - 0.021 14.8 0.3 0.37 10.8 0.0 2.6 2 0 0 2 2 2 0 LisH Aminotran_1_2 PF00155.21 PXF45133.1 - 1e-49 169.7 0.0 1.2e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PXF45133.1 - 3.2e-05 23.4 0.5 6.1e-05 22.4 0.5 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PXF45133.1 - 6.1e-05 22.5 0.5 0.00011 21.7 0.5 1.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 PXF45133.1 - 0.044 12.5 0.2 0.18 10.5 0.2 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain ribosomal_L24 PF17136.4 PXF45134.1 - 4.5e-16 59.0 0.0 1.1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PXF45134.1 - 1.5e-06 28.0 4.4 2.5e-06 27.2 3.3 2.0 2 0 0 2 2 2 1 KOW motif Prot_ATP_ID_OB PF16450.5 PXF45134.1 - 0.069 13.1 0.3 6.8 6.7 0.1 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain PTPLA PF04387.14 PXF45136.1 - 3.4e-45 153.7 7.4 4.5e-45 153.3 7.4 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DNA_ligase_aden PF01653.18 PXF45137.1 - 2.3e-72 243.8 0.0 6.1e-59 199.7 0.0 3.0 1 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF45137.1 - 9.9e-27 92.7 2.9 1.8e-26 91.8 0.8 2.4 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_5 PF14520.6 PXF45137.1 - 4.6e-09 36.8 0.4 0.0017 19.0 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 PXF45137.1 - 1.3e-08 34.8 0.5 1.8e-06 28.0 0.1 3.1 2 1 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 PXF45137.1 - 7.3e-06 26.3 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain 5_3_exonuc PF01367.20 PXF45137.1 - 0.071 13.7 0.5 4.9 7.8 0.0 3.3 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold IMS_HHH PF11798.8 PXF45137.1 - 0.31 11.5 0.9 1.8 9.0 0.1 2.5 2 0 0 2 2 2 0 IMS family HHH motif DNA_ligase_ZBD PF03119.16 PXF45137.1 - 0.41 10.7 2.5 1.3 9.1 2.5 2.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Phage_holin_7_1 PF16081.5 PXF45138.1 - 0.0047 17.1 0.2 0.0074 16.5 0.2 1.3 1 0 0 1 1 1 1 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF2470 PF10615.9 PXF45139.1 - 2.2e-05 25.0 0.0 6.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) Peptidase_M22 PF00814.25 PXF45140.1 - 1.2e-84 284.3 0.1 1.4e-84 284.1 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 PXF45140.1 - 0.002 17.8 0.2 0.015 15.0 0.0 2.0 1 1 1 2 2 2 1 Carbamoyltransferase N-terminus BcrAD_BadFG PF01869.20 PXF45140.1 - 0.051 13.1 0.1 1 8.8 0.1 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family IlvN PF07991.12 PXF45141.1 - 2e-35 121.8 0.2 3.7e-35 120.9 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 PXF45141.1 - 4.2e-33 114.7 0.0 1.2e-24 87.2 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain Uma2 PF05685.12 PXF45143.1 - 3.3e-25 88.6 0.0 4.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease ECH_2 PF16113.5 PXF45144.1 - 2e-102 343.1 0.0 2.4e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PXF45144.1 - 4.8e-27 94.9 0.0 2.4e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 PXF45147.1 - 3.9e-25 87.5 0.0 4.4e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF45147.1 - 0.0021 18.2 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 PXF45147.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.5 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 PXF45147.1 - 0.05 13.7 0.0 0.086 12.9 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 PXF45147.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif MTS PF05175.14 PXF45148.1 - 5.5e-15 55.3 0.0 7.3e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PXF45148.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF45148.1 - 9.9e-10 39.0 0.1 1.1e-08 35.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF45148.1 - 1.6e-08 35.1 0.2 8.8e-07 29.5 0.2 2.8 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PXF45148.1 - 1.7e-07 30.9 0.1 2.8e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 PXF45148.1 - 5.5e-07 30.1 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 PXF45148.1 - 1.4e-06 28.2 0.0 3.2e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45148.1 - 7.7e-05 23.4 0.1 0.00036 21.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PXF45148.1 - 9.8e-05 22.1 0.1 0.00095 18.9 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 PXF45148.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 PXF45148.1 - 0.00046 19.9 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 PXF45148.1 - 0.00052 19.8 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_4 PF02390.17 PXF45148.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 PXF45148.1 - 0.021 14.4 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 PXF45148.1 - 0.052 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PXF45148.1 - 0.063 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PXF45148.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Eco57I PF07669.11 PXF45148.1 - 0.22 12.1 0.0 0.38 11.3 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase DUF938 PF06080.12 PXF45148.1 - 0.26 11.0 0.0 0.49 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NOT2_3_5 PF04153.18 PXF45149.1 - 3.4e-24 85.4 3.2 3.4e-24 85.4 3.2 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Ribosomal_L22e PF01776.17 PXF45150.1 - 3.2e-46 156.2 3.9 3.6e-46 156.0 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF1912 PF08930.10 PXF45150.1 - 0.13 12.4 2.8 0.081 13.1 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) SHMT PF00464.19 PXF45152.1 - 8.6e-183 607.4 0.0 1e-182 607.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 PXF45152.1 - 7e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PXF45152.1 - 0.018 14.2 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Metallophos PF00149.28 PXF45153.1 - 5.9e-10 40.0 0.5 9.1e-10 39.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF45153.1 - 0.0044 17.2 0.0 0.02 15.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SNF2_N PF00176.23 PXF45154.1 - 2.5e-40 138.3 0.4 4.1e-40 137.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF45154.1 - 4.2e-14 52.8 0.0 8.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 PXF45154.1 - 1e-09 38.1 10.5 2.1e-09 37.1 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF45154.1 - 4.6e-07 29.6 8.6 9e-07 28.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF45154.1 - 7.4e-07 28.9 8.6 1.4e-06 28.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF45154.1 - 1.3e-06 28.6 8.4 2.7e-06 27.6 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF45154.1 - 0.00011 22.2 6.0 0.00023 21.1 6.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 PXF45154.1 - 0.00014 21.9 8.2 0.0003 20.9 8.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 PXF45154.1 - 0.00014 21.6 3.8 0.00036 20.3 3.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PXF45154.1 - 0.00048 19.9 3.1 0.00048 19.9 3.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PXF45154.1 - 0.0019 17.9 8.2 0.0042 16.9 8.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 PXF45154.1 - 0.0031 17.5 6.6 0.0076 16.2 6.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PXF45154.1 - 0.0067 16.3 9.6 0.1 12.5 10.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PXF45154.1 - 0.015 15.5 9.2 0.027 14.6 9.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 PXF45154.1 - 0.018 14.9 0.9 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif ResIII PF04851.15 PXF45154.1 - 0.02 14.9 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-UDP PF14569.6 PXF45154.1 - 0.022 14.9 4.5 0.058 13.5 4.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 PXF45154.1 - 1.1 9.6 8.3 4.7 7.6 8.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 PXF45154.1 - 1.2 8.9 7.7 2.8 7.8 7.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SNF2_N PF00176.23 PXF45155.1 - 1.1e-13 50.7 0.0 1.6e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 PXF45155.1 - 5.8e-08 32.6 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Mem_trans PF03547.18 PXF45156.1 - 3.3e-17 62.0 12.7 3.6e-14 52.0 4.3 2.7 2 1 0 2 2 2 2 Membrane transport protein DUF4282 PF14110.6 PXF45156.1 - 2.9 8.7 9.7 0.29 11.9 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF1129 PF06570.11 PXF45156.1 - 5.3 6.5 7.0 1 8.8 1.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 PXF45157.1 - 1.9e-76 256.9 0.0 2.2e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45157.1 - 2.9e-44 151.3 0.0 3.5e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45157.1 - 3e-05 23.5 0.0 7.7e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF45157.1 - 0.00055 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF45157.1 - 0.0015 18.5 5.9 0.004 17.1 0.1 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF45157.1 - 0.023 13.5 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PXF45157.1 - 0.028 14.0 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PXF45157.1 - 0.039 13.5 0.0 0.072 12.7 0.0 1.4 1 1 0 1 1 1 0 RIO1 family OB_NTP_bind PF07717.16 PXF45158.1 - 1.5e-19 70.2 0.0 3.6e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PXF45158.1 - 1.1e-16 61.0 0.0 9.6e-15 54.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PXF45158.1 - 5.8e-13 49.2 0.0 1.5e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF45158.1 - 7.1e-12 45.4 0.1 1.4e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PXF45158.1 - 8.6e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF45158.1 - 0.00028 20.1 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 PXF45158.1 - 0.0048 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 PXF45158.1 - 0.016 15.5 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PXF45158.1 - 0.021 14.5 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 PXF45158.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 PXF45158.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 PXF45158.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 PXF45158.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region BRCT PF00533.26 PXF45159.1 - 0.12 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sel1 PF08238.12 PXF45161.1 - 2.5e-10 40.7 0.1 0.0011 19.6 0.0 2.7 3 0 0 3 3 3 2 Sel1 repeat FtsZ_C PF12327.8 PXF45161.1 - 0.015 15.6 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 FtsZ family, C-terminal domain O-FucT PF10250.9 PXF45162.1 - 2.3e-06 27.6 0.1 6.1e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3619 PF12279.8 PXF45162.1 - 1.7 9.0 6.5 5.1 7.4 3.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) L27 PF02828.16 PXF45163.1 - 0.065 13.0 0.0 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 L27 domain LCM PF04072.14 PXF45164.1 - 2.8e-20 73.0 0.0 6e-20 72.0 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1780 PF08682.10 PXF45164.1 - 0.06 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) DUF87 PF01935.17 PXF45165.1 - 0.17 12.0 0.5 0.25 11.4 0.5 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Metal_resist PF13801.6 PXF45165.1 - 0.69 10.1 3.0 0.75 10.0 1.8 1.6 1 1 0 1 1 1 0 Heavy-metal resistance DUF382 PF04037.13 PXF45166.1 - 3.6e-48 162.9 1.6 3.6e-48 162.9 1.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 PXF45166.1 - 2e-21 75.6 1.1 4.7e-21 74.4 1.1 1.7 1 0 0 1 1 1 1 PSP Erv26 PF04148.13 PXF45167.1 - 1.9e-42 145.4 6.1 2.5e-42 145.1 6.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 M20_dimer PF07687.14 PXF45168.1 - 9e-18 64.2 0.2 1.6e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 PXF45168.1 - 6e-17 62.0 0.0 1.9e-16 60.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Asparaginase_2 PF01112.18 PXF45169.1 - 3.7e-95 318.5 10.3 4.5e-95 318.2 10.3 1.0 1 0 0 1 1 1 1 Asparaginase TPT PF03151.16 PXF45170.1 - 1.3e-12 47.7 18.2 1.6e-12 47.4 18.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF45170.1 - 0.00055 20.1 36.2 0.057 13.6 14.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TIG PF01833.24 PXF45171.1 - 1e-19 70.4 4.9 4.2e-10 39.6 0.9 2.9 2 0 0 2 2 2 2 IPT/TIG domain GSDH PF07995.11 PXF45171.1 - 5.8e-07 29.1 0.4 1.6e-06 27.6 0.4 1.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase HYR PF02494.16 PXF45171.1 - 0.027 14.8 0.1 13 6.2 0.0 2.9 2 0 0 2 2 2 0 HYR domain DEAD PF00270.29 PXF45172.1 - 8.2e-51 172.2 0.0 1.3e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF45172.1 - 6.1e-32 110.3 0.0 6.5e-31 107.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF45172.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF45172.1 - 0.085 13.1 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain TIG PF01833.24 PXF45173.1 - 4.2e-19 68.4 0.2 2e-08 34.2 0.0 3.3 3 0 0 3 3 3 2 IPT/TIG domain HYR PF02494.16 PXF45173.1 - 0.0062 16.8 0.0 0.024 15.0 0.0 2.0 1 0 0 1 1 1 1 HYR domain YfcL PF08891.11 PXF45174.1 - 0.18 12.2 4.3 1.1 9.6 0.1 3.3 3 1 1 4 4 4 0 YfcL protein Methyltransf_25 PF13649.6 PXF45175.1 - 1.4e-11 44.9 0.0 3.8e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF45175.1 - 8.4e-11 42.4 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF45175.1 - 9.1e-10 38.4 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PXF45175.1 - 1.1e-07 31.8 0.0 5.2e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF45175.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF45175.1 - 6.1e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PXF45175.1 - 5.7e-05 23.1 0.1 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45175.1 - 0.00012 22.7 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PXF45175.1 - 0.00023 20.2 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 PXF45175.1 - 0.00025 20.5 0.0 0.0006 19.3 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB CMAS PF02353.20 PXF45175.1 - 0.00045 19.6 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 PXF45175.1 - 0.00069 19.5 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.19 PXF45175.1 - 0.0041 17.2 0.0 0.01 16.0 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 PXF45175.1 - 0.0096 16.9 0.0 0.021 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF45175.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 PXF45175.1 - 0.037 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 PXF45175.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 PXF45175.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Anoctamin PF04547.12 PXF45176.1 - 1.8e-90 303.9 12.9 2.1e-90 303.7 12.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF92 PF01940.16 PXF45177.1 - 1.8e-43 148.6 17.3 4.7e-43 147.3 17.3 1.6 1 1 0 1 1 1 1 Integral membrane protein DUF92 DUF3851 PF12962.7 PXF45177.1 - 0.075 13.3 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Transgly_assoc PF04226.13 PXF45177.1 - 0.098 12.9 0.2 0.098 12.9 0.2 2.5 3 0 0 3 3 3 0 Transglycosylase associated protein 5TM-5TMR_LYT PF07694.12 PXF45177.1 - 0.68 9.4 14.6 0.039 13.5 4.5 2.5 3 0 0 3 3 3 0 5TMR of 5TMR-LYT PEN-2 PF10251.9 PXF45178.1 - 1.1e-12 48.2 3.0 1.7e-12 47.6 3.0 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase CrgA PF06781.12 PXF45178.1 - 0.0067 16.5 1.0 0.3 11.2 0.0 2.4 1 1 1 2 2 2 1 Cell division protein CrgA DUF485 PF04341.12 PXF45178.1 - 0.0073 16.2 0.0 3.6 7.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF485 DUF2269 PF10027.9 PXF45178.1 - 0.021 14.9 0.2 0.036 14.1 0.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) MFS_1 PF07690.16 PXF45178.1 - 0.032 13.2 0.4 0.044 12.7 0.4 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily RNF111_N PF15303.6 PXF45178.1 - 0.056 13.2 5.7 0.072 12.9 5.7 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3464 PF11947.8 PXF45178.1 - 0.058 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MMtag PF10159.9 PXF45178.1 - 0.059 13.7 2.0 0.15 12.4 2.0 1.7 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Choline_transpo PF04515.12 PXF45178.1 - 0.13 11.4 1.5 0.18 11.0 1.5 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Peptidase_S49_N PF08496.10 PXF45178.1 - 1.3 9.1 5.3 0.21 11.7 1.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HEAT PF02985.22 PXF45179.1 - 0.00038 20.5 1.0 0.15 12.4 0.1 3.5 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 PXF45179.1 - 0.0068 16.8 1.4 1e+02 3.4 0.1 3.3 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 PXF45179.1 - 0.24 11.9 3.0 8 7.1 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat Bacillus_HBL PF05791.11 PXF45180.1 - 0.018 14.9 20.6 0.23 11.3 4.6 3.6 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) PKcGMP_CC PF16808.5 PXF45180.1 - 0.11 12.3 0.7 0.32 10.9 0.7 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Baculo_PEP_C PF04513.12 PXF45180.1 - 0.13 12.3 21.7 0.11 12.5 2.4 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 PXF45180.1 - 0.16 11.4 23.3 2.3 7.6 0.1 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 Spc7 PF08317.11 PXF45180.1 - 0.26 10.1 24.9 0.012 14.5 11.4 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 PXF45180.1 - 0.35 10.4 21.0 0.12 12.0 8.0 3.1 3 0 0 3 3 3 0 Intermediate filament protein YabA PF06156.13 PXF45180.1 - 0.49 11.0 12.6 1.4 9.6 1.9 4.0 2 1 3 5 5 5 0 Initiation control protein YabA DASH_Dad2 PF08654.10 PXF45180.1 - 0.62 10.5 6.8 0.32 11.5 2.7 2.6 1 1 0 2 2 2 0 DASH complex subunit Dad2 MPS2 PF17060.5 PXF45180.1 - 0.89 8.7 9.3 2.6 7.2 2.6 2.2 1 1 0 2 2 2 0 Monopolar spindle protein 2 APG6_N PF17675.1 PXF45180.1 - 1 9.9 20.1 2.5 8.7 9.8 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region TMCO5 PF14992.6 PXF45180.1 - 1.7 8.1 14.1 0.51 9.9 6.8 2.5 2 1 0 3 3 3 0 TMCO5 family DUF1664 PF07889.12 PXF45180.1 - 2.9 7.9 10.5 2.1 8.4 3.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ING PF12998.7 PXF45180.1 - 3.8 8.2 12.0 1.4 9.5 1.1 3.7 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding LMBR1 PF04791.16 PXF45180.1 - 4 6.2 6.5 5.7 5.7 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Jnk-SapK_ap_N PF09744.9 PXF45180.1 - 4.2 7.6 21.5 0.6 10.3 9.7 3.1 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 PXF45180.1 - 5.5 7.7 23.6 7 7.3 0.2 4.1 3 2 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PI_PP_I PF18363.1 PXF45180.1 - 7.6 6.8 7.6 8.3 6.7 0.3 3.4 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain Lipocalin_2 PF08212.12 PXF45181.1 - 2.7e-08 33.9 0.0 6.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Lipocalin-like domain ABC_tran PF00005.27 PXF45182.1 - 3.8e-47 160.2 0.1 1.1e-24 87.5 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_CTD PF16326.5 PXF45182.1 - 1.5e-13 50.7 0.7 1.5e-13 50.7 0.7 2.5 2 0 0 2 2 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 PXF45182.1 - 3.6e-12 46.7 8.5 0.00056 19.8 0.2 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PXF45182.1 - 4.1e-09 36.6 4.0 0.00073 19.5 0.3 3.0 3 0 0 3 3 3 2 RsgA GTPase SMC_N PF02463.19 PXF45182.1 - 5.4e-08 32.5 0.3 0.082 12.3 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 PXF45182.1 - 3.5e-07 30.2 4.1 3.5e-07 30.2 4.1 3.2 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 PXF45182.1 - 3.7e-07 30.2 1.5 0.023 14.8 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PXF45182.1 - 0.00013 22.4 8.6 0.28 11.6 0.4 3.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PXF45182.1 - 0.00016 21.3 4.6 0.02 14.6 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 PXF45182.1 - 0.00026 20.6 0.8 0.0091 15.6 0.3 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 PXF45182.1 - 0.00066 19.9 0.2 0.9 9.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 PXF45182.1 - 0.001 18.8 0.0 1.8 8.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 PXF45182.1 - 0.0013 18.4 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 PXF45182.1 - 0.0015 19.1 3.5 13 6.2 0.0 4.0 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 PXF45182.1 - 0.039 14.0 12.0 1.1 9.3 0.1 4.4 4 1 0 4 4 4 0 Helicase HerA, central domain AAA_28 PF13521.6 PXF45182.1 - 0.041 14.1 0.7 18 5.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PXF45182.1 - 0.043 14.2 0.1 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 PXF45182.1 - 0.047 14.1 0.2 20 5.6 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PXF45182.1 - 0.059 13.1 0.8 1.9 8.1 0.2 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 PXF45182.1 - 0.067 13.7 0.2 15 6.1 0.0 3.4 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 PXF45182.1 - 0.079 11.9 5.5 0.17 10.8 0.4 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 PXF45182.1 - 0.08 12.9 3.9 4.6 7.2 0.2 3.7 3 1 0 4 4 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 PXF45182.1 - 0.14 12.3 5.8 0.66 10.0 0.5 3.3 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 PXF45182.1 - 0.15 11.6 0.2 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2347 PF09804.9 PXF45182.1 - 0.15 11.6 0.8 0.69 9.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) CLP1_P PF16575.5 PXF45182.1 - 0.18 11.6 4.7 8.4 6.1 0.0 3.9 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ras PF00071.22 PXF45182.1 - 0.2 11.3 1.0 2.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Ras family NACHT PF05729.12 PXF45182.1 - 0.22 11.4 1.2 4.5 7.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 PXF45182.1 - 3.2 8.0 7.9 11 6.2 0.2 4.1 3 1 1 4 4 4 0 AAA domain IMD PF08397.11 PXF45182.1 - 3.4 7.0 13.2 0.094 12.1 1.1 2.5 2 0 0 2 2 2 0 IRSp53/MIM homology domain ELO PF01151.18 PXF45183.1 - 4.9e-58 196.6 25.3 5.9e-58 196.3 25.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pam17 PF08566.10 PXF45183.1 - 0.025 14.4 0.8 0.037 13.9 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Acyltransf_C PF16076.5 PXF45184.1 - 8.1e-16 57.9 0.2 1.7e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 PXF45184.1 - 2.8e-15 56.1 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF3458_C PF17432.2 PXF45185.1 - 1.4e-109 366.3 0.3 2e-109 365.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 PXF45185.1 - 2.7e-48 164.4 0.1 4.6e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 PXF45185.1 - 8.3e-25 87.1 0.2 4.5e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PXF45185.1 - 3.5e-16 59.9 0.0 6.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 PXF45185.1 - 0.016 15.6 0.1 0.39 11.1 0.1 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ERAP1_C PF11838.8 PXF45185.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain RrnaAD PF00398.20 PXF45186.1 - 2.4e-61 207.1 0.0 3.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PXF45186.1 - 1.8e-07 31.8 0.0 5.3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF45186.1 - 0.00017 22.2 0.0 0.00056 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF45186.1 - 0.0002 21.3 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PXF45186.1 - 0.00042 19.9 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PXF45186.1 - 0.00081 20.1 0.0 0.0021 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PXF45186.1 - 0.0025 17.2 0.1 0.0079 15.5 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain NodS PF05401.11 PXF45186.1 - 0.0054 16.4 0.1 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) PCMT PF01135.19 PXF45186.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PXF45186.1 - 0.0098 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF45186.1 - 0.048 13.1 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 PXF45186.1 - 0.062 13.0 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 PXF45186.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 PXF45186.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Met_10 PF02475.16 PXF45186.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Y_phosphatase2 PF03162.13 PXF45187.1 - 7.3e-52 175.3 0.0 9.4e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PXF45187.1 - 7e-05 22.9 0.0 0.00036 20.6 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PXF45187.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Adap_comp_sub PF00928.21 PXF45188.1 - 2e-48 165.1 0.0 2.5e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PXF45188.1 - 3.1e-05 23.9 0.1 0.00011 22.1 0.1 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Inhibitor_Mig-6 PF11555.8 PXF45188.1 - 1.8 8.7 5.0 0.94 9.6 0.3 2.6 3 0 0 3 3 3 0 EGFR receptor inhibitor Mig-6 DAP3 PF10236.9 PXF45189.1 - 4.8e-18 65.4 0.0 1.1e-17 64.2 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 PXF45189.1 - 2.1e-08 34.7 0.0 8.8e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PXF45189.1 - 0.001 19.3 0.0 0.011 16.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PXF45189.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 PXF45189.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 PXF45189.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 PXF45189.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PXF45189.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 PXF45190.1 - 7.1e-32 110.3 11.2 7.1e-32 110.3 11.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PAXNEB PF05625.11 PXF45190.1 - 0.24 10.5 0.1 0.32 10.1 0.1 1.1 1 0 0 1 1 1 0 PAXNEB protein B-block_TFIIIC PF04182.12 PXF45191.1 - 7.1e-09 35.7 0.0 7e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.12 PXF45191.1 - 0.022 14.1 2.3 0.27 10.5 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.17 PXF45191.1 - 0.099 12.5 0.5 0.49 10.3 0.5 2.2 1 0 0 1 1 1 0 TFIIE alpha subunit Exo84_C PF16528.5 PXF45191.1 - 0.15 11.9 0.7 0.52 10.1 0.2 2.2 2 0 0 2 2 2 0 Exocyst component 84 C-terminal MSA-2c PF12238.8 PXF45191.1 - 1.5 8.8 5.1 4.5 7.2 0.0 2.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c Exostosin PF03016.15 PXF45194.1 - 4.3e-49 167.4 0.0 5.3e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Glyco_transf_90 PF05686.12 PXF45196.1 - 1.5e-22 80.1 0.0 4.5e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Methyltransf_21 PF05050.12 PXF45197.1 - 1.6e-10 41.3 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 PXF45197.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Glyco_transf_64 PF09258.10 PXF45198.1 - 5.7e-42 143.7 0.0 8.2e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 PXF45198.1 - 5.4e-15 55.6 0.4 3.6e-13 49.7 0.4 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PXF45198.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Urm1 PF09138.11 PXF45199.1 - 3.9e-35 120.1 0.1 4.3e-35 120.0 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 PXF45199.1 - 1.5e-05 25.5 0.0 1.9e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 ThiS family DUF5021 PF16424.5 PXF45199.1 - 0.22 11.3 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) DDE_1 PF03184.19 PXF45202.1 - 5.1e-22 78.3 0.0 8.4e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF45202.1 - 0.0082 16.1 0.3 0.016 15.2 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain LPMO_10 PF03067.15 PXF45207.1 - 2.7e-16 60.8 1.0 4.1e-16 60.2 1.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cupin_2 PF07883.11 PXF45208.1 - 5e-05 22.9 6.6 0.11 12.2 0.0 3.9 2 2 4 6 6 6 2 Cupin domain AraC_binding PF02311.19 PXF45208.1 - 0.0028 17.5 0.3 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain Dmd PF17587.2 PXF45209.1 - 0.1 13.0 2.1 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 Discriminator of mRNA degradation Abhydrolase_6 PF12697.7 PXF45210.1 - 1.4e-05 25.8 0.4 1.8e-05 25.4 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 PXF45210.1 - 0.0062 15.1 0.0 0.16 10.5 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 PXF45210.1 - 0.0063 15.5 0.5 0.015 14.2 0.5 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 PXF45210.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF45210.1 - 0.066 12.5 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AIM3 PF17096.5 PXF45211.1 - 4.3 8.3 7.2 1.1e+02 3.8 7.2 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DNA_pol_B_exo1 PF03104.19 PXF45212.1 - 3.1e-06 26.6 0.0 3.8e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain YqaJ PF09588.10 PXF45213.1 - 0.0014 18.8 0.0 0.0076 16.4 0.0 2.1 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain Trypsin PF00089.26 PXF45216.1 - 1.2e-36 126.6 0.0 1.5e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin TTR-52 PF01060.23 PXF45218.1 - 0.012 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family TatD_DNase PF01026.21 PXF45219.1 - 0.0093 15.4 0.0 24 4.2 0.0 3.6 4 0 0 4 4 4 2 TatD related DNase DUF5072 PF16807.5 PXF45219.1 - 0.14 12.2 0.0 88 3.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5072) PSI_PsaE PF02427.17 PXF45219.1 - 0.17 11.6 5.0 8.8 6.1 0.1 4.0 4 0 0 4 4 4 0 Photosystem I reaction centre subunit IV / PsaE InPase PF18823.1 PXF45219.1 - 4.3 7.0 7.9 45 3.7 0.1 3.7 4 0 0 4 4 4 0 Inorganic Pyrophosphatase zf-Nse PF11789.8 PXF45221.1 - 2.5e-08 33.6 0.7 4.8e-08 32.7 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PXF45221.1 - 0.0074 16.3 0.1 0.019 15.0 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger C_GCAxxG_C_C PF09719.10 PXF45221.1 - 0.15 12.4 0.1 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) PT-VENN PF04829.13 PXF45222.1 - 0.11 12.6 1.8 0.45 10.6 0.4 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Iso_dh PF00180.20 PXF45224.1 - 1.9e-67 227.9 0.0 2.3e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GST_N_3 PF13417.6 PXF45226.1 - 5.4e-16 58.8 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF45226.1 - 1.7e-11 44.3 0.0 3.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PXF45226.1 - 1.5e-06 28.4 0.0 3.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF45226.1 - 0.0026 17.7 0.0 0.0089 16.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PXF45226.1 - 0.015 15.5 0.0 0.087 13.1 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin GST_C_3 PF14497.6 PXF45226.1 - 0.024 14.8 0.0 0.085 13.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.21 PXF45227.1 - 5e-11 42.5 13.3 2.1e-10 40.5 11.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF45227.1 - 3.8e-08 33.3 17.0 6.5e-08 32.5 11.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper Noelin-1 PF12308.8 PXF45227.1 - 0.061 13.3 1.1 0.1 12.6 1.1 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF4472 PF14739.6 PXF45227.1 - 0.11 13.3 5.0 2.8 8.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) GBP_C PF02841.14 PXF45227.1 - 0.96 8.8 6.6 1.5 8.2 6.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3584 PF12128.8 PXF45227.1 - 2.6 5.4 9.6 3.1 5.2 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DMRL_synthase PF00885.19 PXF45228.1 - 2.7e-48 163.4 0.6 3.1e-48 163.2 0.6 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Rubrerythrin PF02915.17 PXF45229.1 - 0.0014 19.0 6.5 0.0066 16.8 6.5 1.9 1 1 0 1 1 1 1 Rubrerythrin DnaG_DnaB_bind PF08278.11 PXF45229.1 - 0.0056 17.3 1.6 0.01 16.4 0.8 1.8 1 1 1 2 2 2 1 DNA primase DnaG DnaB-binding Sel1 PF08238.12 PXF45230.1 - 1.8e-67 222.2 14.7 4.6e-07 30.3 0.0 19.5 20 0 0 20 20 20 12 Sel1 repeat TPR_6 PF13174.6 PXF45230.1 - 3.2e-11 43.1 26.4 0.56 11.0 0.1 14.5 16 1 0 16 16 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF45230.1 - 1.7e-06 27.7 38.2 0.14 12.3 0.2 14.8 15 3 3 18 18 15 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF45230.1 - 0.0011 19.5 33.9 1.1 9.9 0.1 10.7 9 3 3 12 12 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF45230.1 - 0.0028 17.9 23.8 0.79 10.1 0.2 10.1 10 2 0 10 10 9 1 Tetratricopeptide repeat Glutaminase PF04960.15 PXF45230.1 - 0.0037 16.5 0.1 0.11 11.6 0.0 2.8 3 0 0 3 3 3 1 Glutaminase TPR_14 PF13428.6 PXF45230.1 - 0.012 16.4 47.6 1.3 10.0 0.1 16.5 15 7 8 23 23 20 0 Tetratricopeptide repeat Tad PF13400.6 PXF45230.1 - 0.015 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like TPR_1 PF00515.28 PXF45230.1 - 0.031 14.1 29.4 14 5.7 0.2 11.0 11 0 0 11 11 11 0 Tetratricopeptide repeat YqaH PF17448.2 PXF45230.1 - 0.23 11.8 1.2 4.4 7.7 0.2 3.7 4 0 0 4 4 3 0 Uncharacterized YqaH-like TPR_2 PF07719.17 PXF45230.1 - 1.4 9.3 41.5 3.7 7.9 0.2 12.2 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45230.1 - 1.5 9.3 31.6 12 6.4 0.3 10.8 12 0 0 12 12 11 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF45230.1 - 4.1 7.7 12.3 49 4.3 1.6 6.4 8 1 0 8 8 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PXF45230.1 - 4.3 7.1 19.2 55 3.6 0.0 8.3 9 0 0 9 9 9 0 TPR repeat DUF1731 PF08338.11 PXF45231.1 - 2.6e-14 52.8 0.0 4.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 PXF45231.1 - 5.1e-13 49.0 0.0 9.7e-13 48.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PXF45231.1 - 6.5e-07 29.4 0.1 1e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PXF45231.1 - 2.9e-05 23.6 0.0 0.0046 16.4 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PXF45231.1 - 0.00013 21.2 0.1 0.043 12.9 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PXF45231.1 - 0.00063 19.0 0.1 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 PXF45231.1 - 0.00086 18.8 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 PXF45231.1 - 0.0013 17.8 0.0 0.0087 15.1 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 PXF45231.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 PXF45231.1 - 0.0087 15.2 0.5 0.078 12.1 0.1 2.2 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 PXF45231.1 - 0.0098 15.5 0.1 0.071 12.7 0.2 2.1 2 1 0 2 2 2 1 NmrA-like family Pyr_redox PF00070.27 PXF45231.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 PXF45231.1 - 0.022 15.2 0.5 0.14 12.6 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Abhydrolase_9 PF10081.9 PXF45231.1 - 0.11 11.5 0.1 1.4 7.9 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta-hydrolase family Cyclin PF08613.11 PXF45232.1 - 1.1e-24 87.6 0.8 2.1e-24 86.7 0.8 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF45232.1 - 3.5e-10 39.7 0.5 5.4e-10 39.1 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain R3H PF01424.22 PXF45234.1 - 7e-07 29.1 0.6 1.4e-06 28.2 0.6 1.5 1 0 0 1 1 1 1 R3H domain R3H-assoc PF13902.6 PXF45234.1 - 0.00014 22.3 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 R3H-associated N-terminal domain RSRP PF17069.5 PXF45234.1 - 0.08 12.5 0.4 0.099 12.2 0.4 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Epimerase PF01370.21 PXF45235.1 - 1e-49 169.2 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF45235.1 - 9.1e-33 114.0 0.0 1.6e-31 110.0 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 PXF45235.1 - 2e-09 36.9 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF45235.1 - 8.1e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PXF45235.1 - 1.5e-06 27.6 0.0 8.1e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 PXF45235.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 PXF45235.1 - 0.00014 21.1 0.0 0.00025 20.2 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PXF45235.1 - 0.0004 19.6 0.0 0.089 11.9 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.13 PXF45235.1 - 0.067 12.7 0.0 0.19 11.2 0.0 1.7 2 1 0 2 2 2 0 NmrA-like family ANAPC4_WD40 PF12894.7 PXF45236.1 - 0.00055 20.2 0.0 0.21 11.9 0.0 3.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 PXF45236.1 - 0.092 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) RisS_PPD PF16524.5 PXF45236.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS CBF PF03914.17 PXF45237.1 - 2.5e-23 83.0 0.0 3.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CBF/Mak21 family Nop53 PF07767.11 PXF45238.1 - 7.5e-28 98.0 27.2 7.5e-28 98.0 27.2 1.5 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) GTP_EFTU PF00009.27 PXF45239.1 - 4.3e-59 199.3 0.1 6.4e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PXF45239.1 - 7.3e-34 116.1 0.1 2.3e-33 114.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 PXF45239.1 - 4.4e-30 103.6 0.0 1.1e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PXF45239.1 - 6.8e-24 83.7 0.2 1.6e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF45239.1 - 2.2e-15 56.8 0.1 8.2e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PXF45239.1 - 3.6e-05 23.6 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AIG1 PF04548.16 PXF45239.1 - 0.0017 17.8 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PXF45239.1 - 0.0018 18.3 0.1 0.0039 17.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 PXF45239.1 - 0.013 15.9 0.0 0.31 11.6 0.0 2.5 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain TFCD_C PF12612.8 PXF45240.1 - 0.018 14.9 0.9 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal NtCtMGAM_N PF16863.5 PXF45240.1 - 0.027 14.6 2.0 0.13 12.4 0.2 2.4 2 1 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase ERCC3_RAD25_C PF16203.5 PXF45241.1 - 2.9e-118 393.5 0.6 7.1e-118 392.2 0.6 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 PXF45241.1 - 2.2e-32 111.9 0.0 4.2e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF45241.1 - 1.2e-14 54.7 0.0 9.8e-14 51.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PXF45241.1 - 1.2e-11 45.0 0.1 2.9e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 PXF45241.1 - 4.2e-05 22.4 0.0 5.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rrn6 PF10214.9 PXF45241.1 - 0.39 9.2 4.2 0.62 8.5 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GAGA_bind PF06217.12 PXF45241.1 - 1.9 8.7 6.0 4 7.6 6.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S49_N PF08496.10 PXF45241.1 - 8.3 6.5 7.9 22 5.1 7.9 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNase_HII PF01351.18 PXF45242.1 - 1.5 8.6 7.7 4.3 7.1 7.7 1.7 1 0 0 1 1 1 0 Ribonuclease HII OTU PF02338.19 PXF45243.1 - 2.8e-16 60.2 0.0 3.3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PXF45243.1 - 1.8e-05 24.4 0.0 0.028 13.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain NMT1 PF09084.11 PXF45244.1 - 8.1e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 PXF45244.1 - 0.018 14.6 0.0 7.5 6.1 0.0 2.3 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 PXF45244.1 - 0.063 12.9 0.1 0.35 10.5 0.0 2.2 1 1 1 2 2 2 0 NMT1-like family LETM1 PF07766.13 PXF45245.1 - 6.7e-14 51.9 0.1 1.3e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein DXP_reductoisom PF02670.16 PXF45246.1 - 1.2e-45 155.4 1.8 2.1e-45 154.6 1.8 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 PXF45246.1 - 1.3e-37 128.6 0.0 2.8e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 PXF45246.1 - 1.7e-36 124.2 0.0 3.6e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 PXF45246.1 - 0.094 13.2 0.0 0.31 11.5 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GCV_H PF01597.19 PXF45247.1 - 2.7e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein NCA2 PF08637.10 PXF45248.1 - 7e-33 114.0 0.6 1.3e-32 113.2 0.6 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DUF842 PF05811.13 PXF45248.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) UPF0004 PF00919.20 PXF45249.1 - 2.8e-25 88.2 0.3 1.5e-24 85.9 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PXF45249.1 - 4e-23 82.6 0.2 4.2e-22 79.3 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 PXF45249.1 - 1.5e-17 63.5 0.1 1.2e-16 60.6 0.0 2.4 2 0 0 2 2 2 1 TRAM domain CLP1_P PF16575.5 PXF45249.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FA_desaturase PF00487.24 PXF45250.1 - 3.8e-21 76.1 15.9 6.5e-20 72.0 15.9 2.3 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 PXF45250.1 - 1.2e-06 27.9 0.0 1.2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Bax1-I PF01027.20 PXF45251.1 - 7.3e-35 120.7 12.5 8.5e-35 120.5 12.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1003 PF06210.11 PXF45251.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF2157 PF09925.9 PXF45251.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1295 PF06966.12 PXF45252.1 - 4.6e-68 229.2 0.9 5.8e-68 228.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 PXF45252.1 - 0.00012 22.1 0.1 0.00024 21.1 0.1 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 PXF45252.1 - 0.00032 21.1 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PXF45252.1 - 0.0014 19.0 0.4 0.004 17.5 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase PGM_PMM_I PF02878.16 PXF45253.1 - 3.1e-32 111.1 0.0 4.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PXF45253.1 - 5.2e-29 100.7 0.0 8.4e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PXF45253.1 - 1.3e-08 35.4 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PXF45253.1 - 6.3e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Atg14 PF10186.9 PXF45259.1 - 0.0075 15.4 1.0 0.012 14.7 1.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 PXF45259.1 - 0.01 16.1 1.4 0.12 12.5 1.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SMC_Nse1 PF07574.13 PXF45259.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Snapin_Pallidin PF14712.6 PXF45259.1 - 0.015 15.7 2.9 0.028 14.8 2.9 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Spc7 PF08317.11 PXF45259.1 - 0.022 13.6 3.0 0.036 12.9 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 PXF45259.1 - 0.058 13.5 3.1 0.13 12.3 3.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.8 PXF45259.1 - 0.06 13.4 1.2 0.14 12.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2524 PF10732.9 PXF45259.1 - 0.16 12.3 2.4 0.29 11.5 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Methyltransf_32 PF13679.6 PXF45260.1 - 1.1e-10 41.7 0.8 8.1e-10 38.9 0.8 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF45260.1 - 2.4e-06 27.2 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain R3H PF01424.22 PXF45260.1 - 6.5e-06 26.0 0.1 1.6e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 R3H domain Methyltransf_31 PF13847.6 PXF45260.1 - 9.8e-06 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF45260.1 - 1.7e-05 25.4 0.2 3.6e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45260.1 - 0.00021 22.0 0.0 0.00044 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PXF45260.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 PXF45260.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 PXF45260.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TIG PF01833.24 PXF45261.1 - 2.9e-05 24.0 0.1 2.9e-05 24.0 0.1 5.4 5 0 0 5 5 5 2 IPT/TIG domain Ribosomal_S3Ae PF01015.18 PXF45262.1 - 2.2e-89 298.4 3.4 2.6e-89 298.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 PXF45262.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PPR_2 PF13041.6 PXF45263.1 - 4e-33 113.4 0.0 1.7e-08 34.5 0.0 6.5 3 2 3 6 6 6 6 PPR repeat family PPR_3 PF13812.6 PXF45263.1 - 7.6e-22 77.2 0.0 0.00016 21.6 0.0 5.6 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 PXF45263.1 - 1.8e-21 74.8 0.2 0.00094 19.3 0.0 7.4 7 1 1 8 8 8 4 PPR repeat PPR_1 PF12854.7 PXF45263.1 - 2.1e-17 62.5 0.0 0.00065 19.4 0.0 5.6 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 PXF45263.1 - 2.2e-15 56.6 2.2 1.3e-08 34.5 0.0 3.9 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP MNE1 PF13762.6 PXF45263.1 - 0.04 13.9 0.1 1.3 8.9 0.1 2.8 2 2 2 4 4 4 0 Mitochondrial splicing apparatus component BTAD PF03704.17 PXF45263.1 - 0.28 11.6 3.3 3.8 7.9 0.2 3.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain CPSase_L_D2 PF02786.17 PXF45264.1 - 1.6e-80 269.5 0.1 2.9e-80 268.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PXF45264.1 - 6.7e-44 148.9 0.1 1.5e-43 147.8 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PXF45264.1 - 1.7e-37 127.8 0.0 3.1e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 PXF45264.1 - 4.2e-12 46.0 0.0 8.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PXF45264.1 - 1.2e-09 38.0 0.0 2.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 PXF45264.1 - 0.00084 19.4 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PXF45264.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 PXF45264.1 - 0.058 13.0 0.0 0.39 10.3 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 PXF45264.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 PXF45264.1 - 0.14 11.6 0.1 0.33 10.4 0.1 1.6 1 1 0 1 1 1 0 ATP-grasp domain ZZ PF00569.17 PXF45265.1 - 2.4e-06 27.3 9.9 2.4e-06 27.3 9.9 2.5 3 0 0 3 3 3 1 Zinc finger, ZZ type Amidinotransf PF02274.17 PXF45267.1 - 5.5e-56 190.1 0.1 1.3e-51 175.7 0.3 3.0 2 1 0 2 2 2 2 Amidinotransferase Ntox27 PF15531.6 PXF45267.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 27 CENP-F_leu_zip PF10473.9 PXF45268.1 - 0.00025 21.1 2.6 0.00025 21.1 2.6 7.7 2 1 3 7 7 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 PXF45268.1 - 0.0044 16.9 3.1 0.0044 16.9 3.1 6.3 1 1 4 6 6 6 3 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 PXF45268.1 - 0.0079 16.4 5.4 0.0079 16.4 5.4 9.2 4 1 6 10 10 10 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 PXF45268.1 - 2.5 6.9 86.1 0.09 11.6 13.2 5.8 1 1 4 5 5 5 0 Spc7 kinetochore protein Snf7 PF03357.21 PXF45269.1 - 3.7e-15 55.9 9.9 5.6e-15 55.4 9.9 1.3 1 0 0 1 1 1 1 Snf7 TRAP_beta PF05753.14 PXF45270.1 - 2.2e-22 79.3 0.0 2.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 PXF45270.1 - 0.15 12.3 0.4 0.74 10.1 0.4 1.9 1 1 0 1 1 1 0 CARDB RRM_1 PF00076.22 PXF45271.1 - 0.11 12.4 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 PXF45271.1 - 0.61 9.4 9.6 1.8 7.8 9.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PXF45271.1 - 1.8 7.5 12.1 3.8 6.5 12.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 PXF45271.1 - 2.4 8.1 18.3 2.4 8.1 12.5 2.7 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 PXF45271.1 - 8 6.5 19.5 19 5.3 19.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PWWP PF00855.17 PXF45272.1 - 6.7e-22 77.7 0.5 8.7e-10 38.9 0.0 2.9 3 0 0 3 3 3 2 PWWP domain SET PF00856.28 PXF45272.1 - 7.6e-20 72.0 0.1 3.2e-19 69.9 0.1 2.1 1 1 0 1 1 1 1 SET domain Agenet PF05641.12 PXF45272.1 - 0.00065 20.1 0.7 0.0018 18.7 0.3 2.0 2 0 0 2 2 2 1 Agenet domain Tudor_3 PF18115.1 PXF45272.1 - 0.0023 17.7 0.6 0.052 13.4 0.4 2.9 2 1 1 3 3 3 1 DNA repair protein Crb2 Tudor domain AWS PF17907.1 PXF45272.1 - 0.014 15.4 3.1 0.014 15.4 3.1 2.2 2 0 0 2 2 2 0 AWS domain Tudor_2 PF18104.1 PXF45272.1 - 0.11 12.3 0.7 0.28 10.9 0.2 2.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 PXF45272.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Methyltr_RsmF_N PF17125.5 PXF45274.1 - 0.016 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF CASP_C PF08172.12 PXF45275.1 - 1.2 8.4 16.4 3.1 7.1 16.4 1.7 1 1 0 1 1 1 0 CASP C terminal PRKG1_interact PF15898.5 PXF45275.1 - 5.5 8.0 22.6 0.051 14.5 12.2 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 PXF45275.1 - 8.8 6.2 9.0 1.3 8.9 2.3 2.6 2 0 0 2 2 2 0 Septum formation initiator C2 PF00168.30 PXF45276.1 - 2e-26 92.3 0.0 5.4e-08 33.1 0.0 6.3 6 0 0 6 6 6 5 C2 domain Vhr1 PF04001.13 PXF45277.1 - 0.038 14.3 1.2 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 Transcription factor Vhr1 BTB PF00651.31 PXF45277.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain YlmH_RBD PF17774.1 PXF45278.1 - 0.00011 22.4 0.5 0.00018 21.7 0.5 1.3 1 0 0 1 1 1 1 Putative RNA-binding domain in YlmH APH PF01636.23 PXF45280.1 - 6.4e-12 45.9 0.7 8.5e-12 45.5 0.2 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF45280.1 - 0.045 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase CLASP_N PF12348.8 PXF45282.1 - 0.0012 18.4 0.9 0.0037 16.8 0.4 2.1 1 1 0 1 1 1 1 CLASP N terminal HHH_9 PF17674.1 PXF45282.1 - 0.052 14.5 0.5 0.28 12.1 0.0 2.4 2 1 1 3 3 3 0 HHH domain zf-4CXXC_R1 PF10497.9 PXF45284.1 - 0.0044 17.2 12.4 0.0086 16.3 12.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Peptidase_C5 PF00770.18 PXF45284.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease zf-SNAP50_C PF12251.8 PXF45284.1 - 0.2 11.3 2.1 0.31 10.7 2.1 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Prim_Zn_Ribbon PF08273.12 PXF45284.1 - 1.5 9.2 5.1 5.7 7.3 5.1 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zinc_ribbon_10 PF10058.9 PXF45284.1 - 2 8.2 6.0 1.6 8.6 3.8 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Spond_N PF06468.13 PXF45285.1 - 4e-29 102.1 0.0 4.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Spondin_N zf-4CXXC_R1 PF10497.9 PXF45286.1 - 0.003 17.8 12.4 0.0061 16.8 12.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Peptidase_C5 PF00770.18 PXF45286.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease zf-SNAP50_C PF12251.8 PXF45286.1 - 0.15 11.7 2.1 0.23 11.1 2.1 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zinc_ribbon_10 PF10058.9 PXF45286.1 - 0.57 10.0 3.8 1.2 9.0 3.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Prim_Zn_Ribbon PF08273.12 PXF45286.1 - 1.3 9.4 5.4 5.5 7.4 5.4 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Spond_N PF06468.13 PXF45288.1 - 4e-29 102.1 0.0 4.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Tim17 PF02466.19 PXF45290.1 - 2.2e-25 89.2 7.0 2.7e-25 88.9 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dak2 PF02734.17 PXF45290.1 - 0.034 14.0 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 DAK2 domain Romo1 PF10247.9 PXF45290.1 - 2 8.8 10.2 2.6 8.5 7.5 2.5 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PP-binding PF00550.25 PXF45291.1 - 6.3e-12 45.7 0.2 8.4e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 PXF45291.1 - 7.6e-05 22.9 0.5 0.00012 22.2 0.5 1.3 1 0 0 1 1 1 1 Acyl-carrier TerB PF05099.13 PXF45291.1 - 0.017 15.1 0.2 0.023 14.7 0.2 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB vATP-synt_E PF01991.18 PXF45292.1 - 4.6e-58 195.9 8.6 5.4e-58 195.7 8.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Afaf PF15339.6 PXF45292.1 - 0.024 14.3 1.1 0.034 13.9 1.1 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Pox_G5 PF04599.12 PXF45292.1 - 0.025 13.6 1.5 0.034 13.2 1.5 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein Peptidase_M29 PF02073.15 PXF45292.1 - 0.039 12.7 3.9 0.049 12.4 3.9 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) DUF223 PF02721.14 PXF45292.1 - 0.053 13.8 1.9 2.2 8.6 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF223 SLED PF12140.8 PXF45292.1 - 0.072 13.6 1.2 2.6 8.6 0.0 2.5 2 1 0 2 2 2 0 SLED domain DUF1104 PF06518.11 PXF45292.1 - 0.086 13.2 4.6 18 5.8 5.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) THOC7 PF05615.13 PXF45292.1 - 0.79 10.0 12.0 1.5 9.1 12.0 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 DUF3135 PF11333.8 PXF45292.1 - 3.7 7.9 6.6 5.1 7.4 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) AAA PF00004.29 PXF45293.1 - 7e-42 143.0 0.0 1.9e-28 99.5 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 PXF45293.1 - 3.9e-15 55.7 0.0 1.1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 PXF45293.1 - 2.7e-10 39.9 0.1 8.3e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PXF45293.1 - 0.0007 20.0 1.4 0.031 14.7 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 PXF45293.1 - 0.00076 19.6 0.0 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PXF45293.1 - 0.00082 19.7 0.1 0.1 12.9 0.0 3.5 3 1 1 4 4 4 1 AAA domain AAA_5 PF07728.14 PXF45293.1 - 0.0014 18.6 0.0 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 PXF45293.1 - 0.024 14.7 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 PXF45293.1 - 0.027 14.6 2.8 0.033 14.3 0.0 2.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 PXF45293.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PXF45293.1 - 0.066 12.9 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 PXF45293.1 - 0.086 13.2 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 PXF45293.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PXF45293.1 - 0.1 12.3 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein TniB PF05621.11 PXF45293.1 - 0.12 11.8 0.1 20 4.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial TniB protein Peptidase_M24 PF00557.24 PXF45294.1 - 2.5e-50 171.1 0.2 2.9e-50 170.9 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Rpn9_C PF18261.1 PXF45294.1 - 0.075 12.6 0.3 0.96 9.1 0.1 2.4 2 0 0 2 2 2 0 Rpn9 C-terminal helix Bromodomain PF00439.25 PXF45295.1 - 3.6e-18 65.4 0.0 6.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 PXF45295.1 - 1.8e-08 34.6 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF45295.1 - 1.8e-06 27.9 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF45295.1 - 0.00019 21.8 0.1 0.00037 20.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Spond_N PF06468.13 PXF45296.1 - 8.1e-27 94.6 0.0 9.6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Spond_N PF06468.13 PXF45297.1 - 4e-29 102.1 0.0 4.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Spondin_N DUF3421 PF11901.8 PXF45300.1 - 4.6e-105 345.7 12.9 4e-33 113.8 0.2 4.3 1 1 3 4 4 4 4 Protein of unknown function (DUF3421) DUF4830 PF16112.5 PXF45300.1 - 0.0015 19.0 0.0 3.4 8.2 0.0 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF4830) Spond_N PF06468.13 PXF45302.1 - 2.3e-26 93.1 0.0 2.9e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Spondin_N DUF3421 PF11901.8 PXF45303.1 - 1.3e-106 350.7 11.9 1.3e-33 115.4 0.2 4.3 1 1 4 5 5 5 5 Protein of unknown function (DUF3421) DUF4830 PF16112.5 PXF45303.1 - 0.0013 19.1 0.0 4 8.0 0.0 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF4830) ACT_6 PF13740.6 PXF45304.1 - 7e-11 42.0 1.2 4.7e-10 39.3 0.3 2.4 2 0 0 2 2 2 1 ACT domain HAD PF12710.7 PXF45304.1 - 1.4e-08 35.3 0.0 2.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF45304.1 - 2.5e-05 24.6 0.6 3.8e-05 24.1 0.6 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_4 PF13291.6 PXF45304.1 - 0.0033 18.0 0.0 0.89 10.2 0.0 2.7 2 1 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 PXF45304.1 - 0.0038 17.0 0.3 0.024 14.4 0.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Yop-YscD_cpl PF16697.5 PXF45304.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain HAD_2 PF13419.6 PXF45304.1 - 0.14 12.3 0.0 0.58 10.2 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CBM_25 PF03423.13 PXF45305.1 - 1.6e-09 37.9 0.1 1.9e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) CBM53 PF16760.5 PXF45305.1 - 1.7e-08 34.9 0.3 0.0056 17.2 0.0 2.3 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) NAT PF04768.13 PXF45306.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase WD40 PF00400.32 PXF45307.1 - 4.3e-18 65.3 7.5 3.9e-06 27.5 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PXF45307.1 - 1.9e-14 53.7 0.1 4.4e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex UPF0184 PF03670.13 PXF45307.1 - 0.027 14.8 2.7 0.057 13.8 2.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) PBP1_TM PF14812.6 PXF45307.1 - 2.3 8.6 11.3 2 8.8 4.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 PXF45307.1 - 3.1 7.8 5.4 0.63 10.1 0.3 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 PXF45307.1 - 3.3 8.4 8.0 1.5 9.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 PXF45307.1 - 5.1 6.8 6.4 0.58 9.8 0.8 2.0 2 0 0 2 2 2 0 FAM176 family Pkinase PF00069.25 PXF45308.1 - 4.8e-42 144.1 0.0 7.6e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45308.1 - 1e-36 126.5 0.0 2.4e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FKBP_C PF00254.28 PXF45309.1 - 4.6e-29 100.6 0.0 6.3e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TAT_signal PF10518.9 PXF45309.1 - 0.0017 18.1 0.3 0.0017 18.1 0.3 2.8 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence DDE_Tnp_1 PF01609.21 PXF45310.1 - 0.008 15.8 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Pribosyltran PF00156.27 PXF45312.1 - 4.2e-20 71.9 0.0 5.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PXF45312.1 - 8.4e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Creatinase_N_2 PF16189.5 PXF45313.1 - 1.1e-51 175.2 0.1 1.5e-50 171.4 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 PXF45313.1 - 9.6e-42 143.0 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 PXF45313.1 - 8.2e-22 77.0 0.2 2.2e-21 75.7 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PXF45313.1 - 9.4e-20 71.6 0.0 4.9e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PI-PLC-X PF00388.19 PXF45314.1 - 1.4e-53 180.3 0.0 3e-53 179.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PXF45314.1 - 4.6e-31 107.5 0.0 1.1e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 PXF45314.1 - 4.7e-11 42.9 0.0 2.2e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH PF00169.29 PXF45314.1 - 0.0002 21.9 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 PXF45314.1 - 0.04 14.3 0.9 0.28 11.5 0.9 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Metallophos PF00149.28 PXF45315.1 - 7.7e-34 118.0 0.3 1.5e-33 117.0 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PXF45315.1 - 0.00014 22.3 0.2 0.00028 21.3 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 PXF45316.1 - 3.9e-08 33.3 16.9 0.012 16.1 0.3 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PXF45316.1 - 9.4e-07 28.5 9.2 0.047 13.4 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PXF45316.1 - 8.6e-05 23.1 17.9 0.097 13.6 0.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF45316.1 - 0.002 17.7 4.0 1.6 8.4 0.1 3.4 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain DUF1677 PF07911.13 PXF45316.1 - 0.0023 18.3 0.5 0.0089 16.4 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1677) zf-met2 PF12907.7 PXF45316.1 - 0.099 12.8 1.6 1.2 9.3 0.3 2.5 2 0 0 2 2 2 0 Zinc-binding OrsD PF12013.8 PXF45316.1 - 0.12 12.8 8.2 15 6.1 0.2 3.6 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Prim_Zn_Ribbon PF08273.12 PXF45316.1 - 0.13 12.6 6.3 0.81 10.0 6.3 2.4 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-met PF12874.7 PXF45316.1 - 0.22 11.9 10.6 12 6.5 0.7 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PXF45316.1 - 0.23 11.8 16.0 3.1 8.2 0.8 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4428 PF14471.6 PXF45316.1 - 0.5 10.3 3.3 3.8 7.5 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_jaz PF12171.8 PXF45316.1 - 0.81 10.0 5.8 7.4 7.0 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Rubredoxin_2 PF18073.1 PXF45316.1 - 2.1 8.1 8.7 24 4.8 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-Di19 PF05605.12 PXF45316.1 - 3.1 8.1 7.8 22 5.5 1.8 2.9 1 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 PXF45316.1 - 4.5 7.4 18.0 1.5 8.9 0.4 3.5 1 1 2 3 3 3 0 BED zinc finger zf-UDP PF14569.6 PXF45321.1 - 0.012 15.7 0.6 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger YqaJ PF09588.10 PXF45321.1 - 0.16 12.2 0.1 0.48 10.6 0.1 1.8 1 1 0 1 1 1 0 YqaJ-like viral recombinase domain CEBP_ZZ PF16366.5 PXF45321.1 - 0.95 9.7 4.4 1.9 8.8 4.4 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Zn_ribbon_17 PF17120.5 PXF45321.1 - 1.5 8.5 5.9 0.25 11.0 1.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Phospholip_B PF04916.13 PXF45322.1 - 0.018 13.7 0.0 0.19 10.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase B DDE_Tnp_1 PF01609.21 PXF45322.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain WXG100 PF06013.12 PXF45323.1 - 0.0075 16.5 0.1 0.082 13.2 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF45323.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF45323.1 - 0.61 10.8 4.6 1.2 9.8 4.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Defensin_big PF14862.6 PXF45324.1 - 0.015 15.6 0.6 0.015 15.6 0.6 1.8 2 0 0 2 2 2 0 Big defensin Defensin_big PF14862.6 PXF45326.1 - 0.0072 16.6 0.6 0.016 15.5 0.6 1.6 1 0 0 1 1 1 1 Big defensin zf-C2H2 PF00096.26 PXF45328.1 - 9.7e-09 35.2 17.3 0.0088 16.4 0.5 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 PXF45328.1 - 8.6e-07 28.6 10.3 0.078 12.7 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 PXF45328.1 - 9e-07 29.2 19.6 0.0077 17.0 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger DUF1677 PF07911.13 PXF45328.1 - 0.00031 21.1 0.8 0.00031 21.1 0.8 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF1677) Prim_Zn_Ribbon PF08273.12 PXF45328.1 - 0.012 15.9 3.4 0.012 15.9 3.4 2.2 3 0 0 3 3 1 0 Zinc-binding domain of primase-helicase zf-met PF12874.7 PXF45328.1 - 0.015 15.7 8.6 32 5.1 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PXF45328.1 - 0.018 15.3 4.1 1.2 9.5 1.1 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 PXF45328.1 - 0.063 13.7 8.8 12 6.4 0.2 3.6 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_11 PF16622.5 PXF45328.1 - 0.076 12.8 0.8 0.076 12.8 0.8 3.5 3 1 0 3 3 3 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 PXF45328.1 - 0.19 11.4 10.0 2.1 8.1 0.2 3.5 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 PXF45328.1 - 0.26 9.8 4.4 0.48 8.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) DUF4428 PF14471.6 PXF45328.1 - 0.3 11.0 2.0 0.99 9.4 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf_UBZ PF18439.1 PXF45328.1 - 0.33 10.6 6.8 16 5.2 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 PXF45328.1 - 0.36 11.2 14.6 2.3 8.6 0.4 4.0 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 PXF45328.1 - 2.4 8.2 7.1 14 5.7 1.3 3.0 1 1 2 3 3 3 0 CpXC protein DZR PF12773.7 PXF45328.1 - 2.4 8.2 11.3 29 4.8 6.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon Rhodanese_C PF12368.8 PXF45328.1 - 2.9 8.3 10.3 7.4 7.0 0.5 2.3 1 1 1 2 2 2 0 Rhodanase C-terminal DUF2387 PF09526.10 PXF45328.1 - 3.4 7.9 6.6 7.3 6.8 1.9 2.7 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-BED PF02892.15 PXF45328.1 - 7.8 6.6 19.6 0.37 10.9 1.4 3.9 1 1 2 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 PXF45330.1 - 1.7e-07 31.3 24.2 0.0025 18.2 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF45330.1 - 1e-06 29.1 25.3 0.0054 17.5 0.7 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF45330.1 - 0.0034 17.1 10.0 0.014 15.1 0.2 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type Vps36-NZF-N PF16988.5 PXF45330.1 - 0.025 13.9 0.0 0.38 10.2 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_6 PF13912.6 PXF45330.1 - 0.067 13.2 0.4 0.067 13.2 0.4 4.7 6 0 0 6 6 6 0 C2H2-type zinc finger zf-Di19 PF05605.12 PXF45330.1 - 0.24 11.7 10.9 0.34 11.2 0.1 3.0 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 PXF45330.1 - 1 9.8 0.1 1 9.8 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.7 PXF45330.1 - 1.3 9.1 15.5 1.6e+03 -0.8 15.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 PXF45330.1 - 4.1 7.5 6.7 2.8 8.0 0.1 2.9 3 0 0 3 3 3 0 YhfH-like protein C1_2 PF03107.16 PXF45330.1 - 6 7.3 17.3 8.9 6.7 0.7 3.7 2 2 1 3 3 3 0 C1 domain Zn-ribbon_8 PF09723.10 PXF45330.1 - 6.6 7.0 17.0 6 7.1 2.4 3.3 2 1 2 4 4 4 0 Zinc ribbon domain ADK_lid PF05191.14 PXF45330.1 - 8.4 6.5 14.1 13 5.9 2.2 2.9 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2 PF00096.26 PXF45331.1 - 1.3e-08 34.8 22.8 0.014 15.8 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF45331.1 - 5.7e-07 29.8 23.9 0.022 15.6 0.7 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PXF45331.1 - 0.024 14.6 2.4 0.024 14.6 2.4 5.8 6 2 0 6 6 6 0 C2H2-type zinc finger zf-3CxxC_2 PF17180.4 PXF45331.1 - 0.032 15.0 10.0 0.032 15.0 10.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain zf-ribbon_3 PF13248.6 PXF45331.1 - 9.2 5.8 10.5 16 5.1 0.3 4.0 4 0 0 4 4 4 0 zinc-ribbon domain HSP20 PF00011.21 PXF45332.1 - 4.5e-11 42.8 0.2 3.5e-10 39.9 0.2 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF45332.1 - 1e-05 25.0 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 PXF45332.1 - 0.00018 21.8 0.0 0.00029 21.2 0.0 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain An_peroxidase PF03098.15 PXF45333.1 - 1.1e-119 400.4 0.0 1.4e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase GRP PF07172.11 PXF45333.1 - 0.0003 21.4 1.1 0.00058 20.5 1.1 1.4 1 0 0 1 1 1 1 Glycine rich protein family An_peroxidase PF03098.15 PXF45334.1 - 2.1e-112 376.4 0.0 2.6e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Abhydrolase_3 PF07859.13 PXF45336.1 - 4.6e-12 46.2 0.2 6.3e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF45336.1 - 7.8e-09 36.5 5.3 1.2e-08 35.9 5.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PXF45336.1 - 2.2e-06 27.3 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 PXF45336.1 - 2.8e-05 24.0 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 PXF45336.1 - 5.3e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 PXF45336.1 - 0.00014 20.8 0.0 0.00023 20.2 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 PXF45336.1 - 0.00072 18.9 0.0 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF45336.1 - 0.0041 16.8 0.1 0.0057 16.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PXF45336.1 - 0.0077 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein AXE1 PF05448.12 PXF45336.1 - 0.033 12.9 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LCAT PF02450.15 PXF45336.1 - 0.072 12.2 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Importin_rep_4 PF18808.1 PXF45337.1 - 1e-23 83.4 3.9 5.5e-23 81.1 0.0 3.8 3 1 1 4 4 4 1 Importin repeat HEAT_2 PF13646.6 PXF45337.1 - 2.8e-17 62.9 11.0 1.4e-05 25.4 0.0 8.2 7 2 2 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 PXF45337.1 - 1.1e-16 60.9 16.5 0.0006 20.3 0.1 8.8 9 1 1 10 10 8 5 HEAT-like repeat HEAT PF02985.22 PXF45337.1 - 4.7e-13 48.2 21.0 0.0054 16.9 0.0 9.7 10 0 0 10 10 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 PXF45337.1 - 4e-11 43.4 0.0 0.061 13.9 0.0 5.6 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 PXF45337.1 - 9e-09 35.4 1.9 1.2 9.0 0.0 7.0 7 2 1 8 8 8 3 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 PXF45337.1 - 2.8e-06 26.2 0.3 0.0011 17.6 0.0 3.2 2 1 0 2 2 2 1 Adaptin N terminal region Arm PF00514.23 PXF45337.1 - 1.4e-05 25.0 1.0 12 6.1 0.1 5.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 PXF45337.1 - 0.00012 21.3 3.6 0.12 11.4 0.2 4.4 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 PXF45337.1 - 0.00019 21.5 0.1 0.17 11.9 0.0 4.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 PXF45337.1 - 0.00084 19.5 0.1 1.1 9.4 0.0 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein IBN_N PF03810.19 PXF45337.1 - 0.00086 19.2 0.0 0.024 14.5 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 PXF45337.1 - 0.002 17.9 0.3 4.7 6.9 0.0 4.5 2 2 1 3 3 3 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 PXF45337.1 - 0.023 14.8 0.1 0.46 10.5 0.0 3.2 2 0 0 2 2 2 0 Exportin 1-like protein Tti2 PF10521.9 PXF45337.1 - 0.034 13.7 0.1 3.2 7.2 0.0 3.2 3 1 1 4 4 4 0 Tti2 family Cnd3 PF12719.7 PXF45337.1 - 0.038 13.2 1.0 0.25 10.5 0.0 2.9 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Surface_antigen PF11054.8 PXF45337.1 - 0.1 12.3 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Sporozoite TA4 surface antigen RTP1_C1 PF10363.9 PXF45337.1 - 0.13 12.5 0.1 15 5.8 0.0 3.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 PXF45337.1 - 1.3 9.9 7.9 56 4.8 0.0 6.0 7 0 0 7 7 4 0 PBS lyase HEAT-like repeat Glyoxalase_4 PF13669.6 PXF45338.1 - 5.8e-08 33.0 0.0 7.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 PXF45338.1 - 1.7e-07 31.5 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_33 PF13671.6 PXF45339.1 - 2.8e-17 63.2 0.3 2e-14 53.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 PXF45339.1 - 2.3e-05 24.0 0.2 0.025 14.0 0.1 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_18 PF13238.6 PXF45339.1 - 3.9e-05 24.2 0.2 0.0073 16.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 PXF45339.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 PXF45339.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase tRNA_lig_kinase PF08303.11 PXF45339.1 - 0.0029 17.7 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_22 PF13401.6 PXF45339.1 - 0.0031 17.8 0.0 0.0037 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PXF45339.1 - 0.0035 17.8 0.2 0.097 13.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 PXF45339.1 - 0.0057 16.6 0.0 0.016 15.1 0.0 1.7 1 1 1 2 2 2 1 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 PXF45339.1 - 0.0082 15.4 0.1 0.044 13.0 0.0 1.9 1 1 1 2 2 2 1 Zeta toxin G-alpha PF00503.20 PXF45339.1 - 0.011 14.9 0.0 0.09 11.9 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 PXF45339.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 PXF45339.1 - 0.016 15.0 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF45339.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PXF45339.1 - 0.062 13.7 0.0 0.096 13.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 PXF45339.1 - 0.063 13.4 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PXF45339.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 PXF45339.1 - 0.069 13.7 0.0 0.076 13.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 PXF45339.1 - 0.079 13.3 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 PXF45339.1 - 0.086 13.0 0.1 7.6 6.6 0.0 2.2 1 1 1 2 2 2 0 Shikimate kinase 6PF2K PF01591.18 PXF45339.1 - 0.09 12.1 0.1 0.25 10.6 0.0 1.6 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Viral_helicase1 PF01443.18 PXF45339.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 PXF45339.1 - 0.11 12.7 0.0 1.3 9.3 0.0 2.0 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 PXF45339.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPBP PF02517.16 PXF45340.1 - 2.1e-14 53.7 8.6 2.1e-14 53.7 8.6 2.7 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Prok_Ub PF14454.6 PXF45342.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic Ubiquitin UQ_con PF00179.26 PXF45343.1 - 1.2e-50 170.8 0.0 1.3e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF45343.1 - 3.3e-06 26.8 0.0 3.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B MSC PF09402.10 PXF45344.1 - 4.8e-19 69.0 0.1 1.5e-18 67.4 0.1 1.7 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 PXF45344.1 - 9.3e-07 28.5 0.2 0.0016 18.1 0.0 2.8 2 0 0 2 2 2 2 HeH/LEM domain Ish1 PF10281.9 PXF45344.1 - 0.00027 21.2 0.1 0.013 15.8 0.1 2.7 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Pkinase PF00069.25 PXF45345.1 - 1.6e-70 237.5 0.0 6.6e-70 235.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45345.1 - 1.1e-32 113.4 0.0 5.1e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PXF45345.1 - 1.5e-07 31.1 0.5 0.019 14.3 0.0 2.9 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 PXF45345.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF45345.1 - 0.028 13.4 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PXF45345.1 - 0.032 13.6 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PXF45345.1 - 0.084 12.5 0.0 0.65 9.6 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SPRY PF00622.28 PXF45346.1 - 2.8e-10 40.4 0.1 2.2e-07 31.0 0.0 3.2 3 0 0 3 3 3 2 SPRY domain CDC50 PF03381.15 PXF45347.1 - 2.2e-65 220.9 0.1 2.6e-65 220.7 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Dpy-30 PF05186.13 PXF45347.1 - 0.039 13.6 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif Glyco_transf_41 PF13844.6 PXF45348.1 - 9e-53 179.3 0.0 6.8e-26 90.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 PXF45348.1 - 4.7e-45 149.6 21.5 5.6e-08 32.3 0.2 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 PXF45348.1 - 1.6e-39 130.8 22.2 5.2e-06 26.2 0.1 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 PXF45348.1 - 2.4e-37 124.6 30.2 9.8e-07 28.7 0.2 9.9 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45348.1 - 1.8e-36 123.6 23.4 1.6e-05 24.5 0.0 9.9 6 2 4 10 10 10 8 TPR repeat TPR_8 PF13181.6 PXF45348.1 - 4.9e-31 104.3 15.1 5.4e-06 26.2 0.0 9.4 12 0 0 12 12 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 PXF45348.1 - 9e-28 96.4 31.1 8.8e-08 32.3 0.1 8.0 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45348.1 - 2.6e-24 83.8 26.5 0.0077 17.0 3.0 10.9 4 3 7 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 PXF45348.1 - 8.1e-22 77.6 26.4 4.9e-07 30.3 0.1 7.4 3 3 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 PXF45348.1 - 2.5e-20 70.9 20.3 0.00081 19.2 0.0 10.2 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 PXF45348.1 - 1.2e-18 67.4 28.0 1.6e-05 25.3 0.7 7.5 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.6 PXF45348.1 - 1.3e-12 47.1 33.0 0.0024 17.7 0.0 10.4 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 PXF45348.1 - 1.4e-12 47.3 9.5 0.0019 18.7 0.1 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat NARP1 PF12569.8 PXF45348.1 - 2.9e-08 33.1 3.5 0.0012 17.9 0.1 3.4 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.9 PXF45348.1 - 4.3e-07 29.7 14.5 0.025 14.1 0.4 4.2 3 1 1 4 4 4 3 Est1 DNA/RNA binding domain TPR_9 PF13371.6 PXF45348.1 - 1.5e-06 28.3 20.2 0.0021 18.2 0.0 6.0 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF45348.1 - 6.1e-05 22.6 16.1 0.025 13.9 1.2 4.9 1 1 5 6 6 6 2 MalT-like TPR region Coatomer_E PF04733.14 PXF45348.1 - 0.0017 17.8 4.4 1.2 8.5 0.1 3.4 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_15 PF13429.6 PXF45348.1 - 0.0034 16.7 9.4 0.31 10.2 0.2 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF1824 PF08854.10 PXF45348.1 - 0.043 13.7 0.2 3.1 7.7 0.0 3.5 2 1 1 4 4 4 0 Domain of unknown function (DUF1824) SNAP PF14938.6 PXF45348.1 - 0.084 12.3 11.8 0.17 11.3 0.2 3.8 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 PXF45348.1 - 0.49 10.5 6.7 13 6.0 0.1 4.1 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 PXF45348.1 - 0.86 9.7 9.3 9.9 6.3 0.0 5.8 6 1 1 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 PXF45348.1 - 7.5 7.5 19.8 69 4.5 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat Pkinase PF00069.25 PXF45350.1 - 6.4e-80 268.3 0.0 8e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45350.1 - 2.7e-42 144.8 0.0 3.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PXF45350.1 - 3.6e-08 33.9 0.0 5.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 PXF45350.1 - 2.9e-07 30.1 0.2 1.9e-05 24.1 0.1 2.3 1 1 1 2 2 2 1 Kinase-like PH_8 PF15409.6 PXF45350.1 - 0.00034 20.8 0.0 0.00077 19.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 PXF45350.1 - 0.0016 17.3 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF45350.1 - 0.003 17.0 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_6 PF15406.6 PXF45350.1 - 0.0057 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 PXF45350.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Imm64 PF15600.6 PXF45350.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 64 DUF1838 PF08894.11 PXF45350.1 - 0.066 12.9 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) DUF2222 PF09984.9 PXF45350.1 - 0.079 12.8 0.3 0.19 11.6 0.3 1.7 1 1 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) Glyoxalase PF00903.25 PXF45350.1 - 0.08 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ssl1 PF04056.14 PXF45351.1 - 6.3e-69 231.7 0.1 1.5e-68 230.5 0.0 1.6 2 0 0 2 2 2 1 Ssl1-like VWA_2 PF13519.6 PXF45351.1 - 1.1e-11 45.3 0.0 2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 PXF45351.1 - 4.2e-09 36.5 14.7 4.2e-09 36.5 14.7 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_3 PF13768.6 PXF45351.1 - 7.9e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 PXF45351.1 - 0.0012 19.0 6.1 0.0012 19.0 6.1 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain DZR PF12773.7 PXF45351.1 - 0.0019 18.2 9.1 2.8 8.0 8.3 2.9 1 1 1 2 2 2 2 Double zinc ribbon VWA PF00092.28 PXF45351.1 - 0.073 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 PXF45351.1 - 0.28 12.0 12.9 13 6.7 8.7 3.3 1 1 1 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 PXF45351.1 - 3.3 7.7 13.3 15 5.6 0.5 3.0 2 1 1 3 3 3 0 zinc-ribbons Peripla_BP_2 PF01497.18 PXF45352.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Podoplanin PF05808.11 PXF45352.1 - 0.2 11.8 0.1 0.34 11.0 0.1 1.3 1 0 0 1 1 1 0 Podoplanin GFO_IDH_MocA PF01408.22 PXF45353.1 - 6.7e-12 46.3 0.0 1.2e-11 45.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MeaB PF03308.16 PXF45353.1 - 0.0081 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRF-TF PF00319.18 PXF45354.1 - 4.8e-22 77.2 0.1 7.8e-22 76.5 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF872 PF05915.12 PXF45356.1 - 7e-09 35.9 0.0 8.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF1129 PF06570.11 PXF45356.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Mito_carr PF00153.27 PXF45357.1 - 3e-47 158.5 2.5 1.6e-18 66.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.29 PXF45357.1 - 2e-36 123.9 0.0 2.6e-18 65.9 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Peptidase_C92 PF05708.12 PXF45357.1 - 3.8e-12 46.6 0.0 3.1e-07 30.6 0.0 2.6 3 0 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family EF-hand_7 PF13499.6 PXF45357.1 - 0.1 13.0 3.7 1.1 9.7 1.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair 14-3-3 PF00244.20 PXF45358.1 - 3.9e-103 343.7 4.1 4.4e-103 343.5 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein HBM PF16591.5 PXF45358.1 - 0.076 12.4 3.5 0.26 10.7 0.0 2.7 3 0 0 3 3 3 0 Helical bimodular sensor domain HMG_box_5 PF14887.6 PXF45358.1 - 0.089 12.8 1.2 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Vps39_2 PF10367.9 PXF45359.1 - 3.1e-18 66.2 0.3 3.1e-18 66.2 0.3 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 PXF45359.1 - 0.0039 17.5 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 TFIID_20kDa PF03847.13 PXF45359.1 - 0.056 13.9 2.0 0.14 12.6 2.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PhyH PF05721.13 PXF45360.1 - 1.4e-13 51.6 0.0 7.3e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2690 PF10901.8 PXF45361.1 - 0.3 11.4 1.4 2.7 8.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2690) Acetyltransf_1 PF00583.25 PXF45363.1 - 9.1e-14 51.7 0.1 1.2e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF45363.1 - 1.7e-09 37.7 0.3 2.1e-09 37.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF45363.1 - 6.9e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF45363.1 - 1e-05 25.4 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PXF45363.1 - 0.01 15.9 0.2 0.019 15.1 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PXF45363.1 - 0.012 15.7 0.3 0.018 15.2 0.3 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF45363.1 - 0.11 13.2 0.1 0.18 12.5 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Vps16_C PF04840.12 PXF45364.1 - 1.3e-30 106.5 0.0 2.9e-30 105.4 0.0 1.5 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.13 PXF45364.1 - 2.7e-30 105.5 0.0 4.8e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region WD40 PF00400.32 PXF45364.1 - 0.1 13.5 0.2 0.43 11.5 0.2 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat AbiEi_4 PF13338.6 PXF45364.1 - 0.8 9.9 2.9 1.8 8.8 0.1 2.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin VWA PF00092.28 PXF45369.1 - 8.9e-09 35.8 0.1 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PXF45369.1 - 0.005 17.5 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain ATP-grasp_4 PF13535.6 PXF45370.1 - 8.8e-22 77.4 0.0 3.3e-21 75.5 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_N PF18130.1 PXF45370.1 - 1e-11 45.2 0.1 3.5e-11 43.5 0.0 2.0 2 0 0 2 2 1 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 PXF45370.1 - 4.3e-10 39.9 0.0 1e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PXF45370.1 - 1.9e-07 30.9 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 PXF45370.1 - 1.4e-06 28.2 0.0 0.00016 21.5 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 PXF45370.1 - 6.2e-05 22.6 0.0 0.00016 21.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 PXF45370.1 - 0.00012 21.7 0.0 0.00068 19.3 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 PXF45370.1 - 0.00022 20.8 0.0 0.001 18.6 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 PXF45370.1 - 0.00079 19.0 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Pribosyltran PF00156.27 PXF45370.1 - 0.005 16.4 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain ATP-grasp_5 PF13549.6 PXF45370.1 - 0.015 14.8 0.0 0.036 13.5 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 PXF45370.1 - 0.021 15.0 0.1 0.088 13.0 0.0 2.1 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 PXF45370.1 - 0.12 11.7 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Metallophos PF00149.28 PXF45371.1 - 2.1e-36 126.4 0.3 2.8e-36 126.0 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 23S_rRNA_IVP PF05635.11 PXF45371.1 - 0.12 12.7 1.2 0.17 12.2 0.5 1.6 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein STPPase_N PF16891.5 PXF45371.1 - 0.13 12.7 0.2 0.28 11.7 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ferritin PF00210.24 PXF45372.1 - 5.4e-30 104.2 4.2 6.7e-30 103.9 4.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF3134 PF11332.8 PXF45373.1 - 1.2e-07 32.0 1.9 1.2e-07 32.0 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3134) PRO8NT PF08082.11 PXF45373.1 - 0.097 12.6 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain FapA PF03961.13 PXF45374.1 - 0.0047 15.6 3.4 0.0053 15.4 3.4 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Vma12 PF11712.8 PXF45374.1 - 8.2 6.5 7.2 12 5.9 7.2 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Beta-lactamase PF00144.24 PXF45375.1 - 3.9e-40 138.1 0.1 3.3e-31 108.7 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase ABC1 PF03109.16 PXF45375.1 - 1.9e-22 79.7 0.0 4.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 PXF45375.1 - 0.00034 20.3 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) PTPLA PF04387.14 PXF45376.1 - 1.6e-59 200.3 10.4 2.6e-59 199.6 10.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ku PF02735.16 PXF45377.1 - 7.4e-24 84.6 0.0 2.2e-23 83.0 0.0 1.8 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 PXF45377.1 - 2e-15 57.2 0.0 4.9e-14 52.6 0.0 2.3 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PXF45377.1 - 1.8e-08 35.0 1.2 7.1e-08 33.0 1.2 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 PXF45377.1 - 7.3e-07 28.8 0.1 1.7e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 SAP domain SAP30_Sin3_bdg PF13867.6 PXF45377.1 - 0.023 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 SNRNP27 PF08648.12 PXF45378.1 - 1.7e-23 82.4 0.1 2.3e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins HAD_2 PF13419.6 PXF45379.1 - 1.7e-20 73.8 0.0 8.6e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF45379.1 - 7.9e-17 62.3 0.5 4.2e-16 59.9 0.6 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF45379.1 - 2.2e-07 30.9 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PXF45379.1 - 0.00046 20.6 0.1 0.0011 19.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PrpR_N PF06506.11 PXF45379.1 - 0.036 13.6 0.2 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Propionate catabolism activator GcpE PF04551.14 PXF45379.1 - 0.071 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 GcpE protein Hydrolase_6 PF13344.6 PXF45379.1 - 0.081 13.0 0.0 7.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF155 PF02582.14 PXF45380.1 - 9.4e-43 146.3 0.0 1.6e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sas10_Utp3 PF04000.15 PXF45381.1 - 2.6e-05 24.8 0.2 8.2e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Proteasome PF00227.26 PXF45382.1 - 4.5e-61 205.7 0.1 6e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF45382.1 - 3.3e-11 42.6 0.0 6.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.27 PXF45383.1 - 4.7e-50 169.7 0.0 2.3e-25 89.7 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PXF45383.1 - 5.9e-22 77.5 3.8 5.9e-22 77.5 3.8 3.9 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 PXF45383.1 - 2.8e-21 76.6 2.1 9.1e-06 25.7 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF45383.1 - 1.2e-10 41.2 3.2 0.0058 16.1 0.0 4.5 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PXF45383.1 - 7.2e-08 32.5 0.0 0.0068 16.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PXF45383.1 - 1.3e-07 31.2 0.0 0.00071 19.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 PXF45383.1 - 2.7e-07 31.0 0.8 0.0015 18.8 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PXF45383.1 - 3.2e-07 30.9 0.6 0.029 14.7 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 PXF45383.1 - 1.9e-06 28.5 7.6 0.014 15.9 0.0 3.4 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 PXF45383.1 - 4.4e-06 26.7 0.0 0.08 13.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF45383.1 - 1.3e-05 25.1 0.1 0.0039 17.1 0.0 3.0 2 1 1 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 PXF45383.1 - 2e-05 24.9 1.1 0.33 11.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 PXF45383.1 - 2.1e-05 25.0 0.1 0.05 14.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PXF45383.1 - 5.1e-05 23.8 0.4 0.16 12.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 PXF45383.1 - 9.1e-05 22.4 0.7 0.063 13.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 PXF45383.1 - 0.00011 22.4 1.7 0.46 10.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 PXF45383.1 - 0.00012 22.1 0.0 0.32 11.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_27 PF13514.6 PXF45383.1 - 0.00021 21.0 0.2 0.23 11.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.9 PXF45383.1 - 0.00033 20.4 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 PXF45383.1 - 0.00048 20.1 0.7 0.05 13.5 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 PXF45383.1 - 0.00052 20.1 1.7 0.56 10.2 0.1 3.2 3 1 0 3 3 3 1 Dynamin family AAA_5 PF07728.14 PXF45383.1 - 0.00055 19.9 1.7 8.1 6.4 0.0 3.9 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PXF45383.1 - 0.00085 19.7 0.0 0.73 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 PXF45383.1 - 0.00088 19.0 0.1 2.4 7.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 PXF45383.1 - 0.0013 18.0 0.0 0.041 13.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 PXF45383.1 - 0.0016 18.2 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PXF45383.1 - 0.0027 17.8 0.1 4.6 7.3 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 PXF45383.1 - 0.0033 17.0 0.1 1.5 8.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 PXF45383.1 - 0.0035 16.9 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 PXF45383.1 - 0.0079 15.9 0.1 0.71 9.5 0.0 2.8 2 1 1 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 PXF45383.1 - 0.01 14.5 1.8 1.4 7.5 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 PXF45383.1 - 0.011 15.3 0.0 6.4 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PXF45383.1 - 0.013 15.5 0.0 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 PXF45383.1 - 0.019 15.2 0.0 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 PXF45383.1 - 0.035 14.3 0.1 4.2 7.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.18 PXF45383.1 - 0.044 13.5 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 PXF45383.1 - 0.091 12.7 0.1 9.3 6.1 0.0 2.8 3 0 0 3 3 2 0 NTPase Arf PF00025.21 PXF45383.1 - 0.093 12.2 1.0 1.2 8.6 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_17 PF13207.6 PXF45383.1 - 0.15 12.5 3.8 8.2 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF4810 PF16068.5 PXF45383.1 - 0.29 11.7 2.3 0.3 11.6 0.2 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4810) DUF1811 PF08838.10 PXF45383.1 - 2.5 8.4 7.1 0.46 10.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF3584 PF12128.8 PXF45383.1 - 4.6 4.6 13.0 0.91 6.9 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) DLIC PF05783.11 PXF45383.1 - 5 5.8 6.9 7.7 5.2 0.0 3.3 4 0 0 4 4 3 0 Dynein light intermediate chain (DLIC) Aldedh PF00171.22 PXF45385.1 - 9.7e-98 327.6 0.0 2e-97 326.6 0.0 1.4 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 PXF45385.1 - 3.5e-58 197.5 0.0 5.2e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 PXF45385.1 - 0.00042 19.8 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.25 PXF45386.1 - 2e-53 181.4 0.0 2.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45386.1 - 7.3e-23 81.2 0.0 9.9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45386.1 - 1e-06 28.3 0.0 2.7e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 PXF45386.1 - 0.0023 18.4 0.1 0.0089 16.5 0.0 2.0 2 0 0 2 2 2 1 PH domain Hint PF01079.20 PXF45387.1 - 2.7e-27 95.7 0.1 4.5e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Hint module Kelch_6 PF13964.6 PXF45387.1 - 1e-20 73.3 19.6 4.5e-05 23.6 0.1 7.1 2 1 5 7 7 7 5 Kelch motif Kelch_1 PF01344.25 PXF45387.1 - 1.3e-18 66.3 15.3 2.5e-06 27.0 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PXF45387.1 - 2.8e-14 53.0 12.6 0.0049 17.1 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PXF45387.1 - 1.3e-10 41.1 16.3 0.0042 17.1 0.0 6.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PXF45387.1 - 1.5e-09 37.7 8.5 0.33 11.0 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 PXF45387.1 - 1.1e-05 25.2 13.7 0.61 10.2 0.0 6.8 6 1 0 6 6 6 3 Kelch motif Vint PF14623.6 PXF45387.1 - 0.032 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Hint-domain PhoLip_ATPase_C PF16212.5 PXF45388.1 - 4.9e-58 196.8 18.3 4.9e-58 196.8 18.3 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PXF45388.1 - 7.8e-21 73.5 0.1 7.8e-21 73.5 0.1 2.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PXF45388.1 - 1.7e-12 48.1 0.1 3.8e-06 27.3 0.1 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PXF45388.1 - 2.9e-09 36.9 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PXF45388.1 - 2.2e-07 30.6 4.4 3.3e-07 30.0 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PXF45388.1 - 0.00085 19.1 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF45388.1 - 0.0058 17.0 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Chloroa_b-bind PF00504.21 PXF45389.1 - 4.7e-35 121.5 0.0 5.9e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SSF PF00474.17 PXF45390.1 - 2e-17 63.1 34.3 2e-17 63.1 34.3 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family PPR_2 PF13041.6 PXF45392.1 - 4.3e-05 23.6 0.0 0.0028 17.8 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 PXF45392.1 - 0.00028 20.9 3.3 0.0044 17.2 0.5 3.7 3 0 0 3 3 3 1 PPR repeat OmpA PF00691.20 PXF45392.1 - 0.019 15.4 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 OmpA family PPR_3 PF13812.6 PXF45392.1 - 0.11 12.6 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 Pentatricopeptide repeat domain COG4 PF08318.12 PXF45393.1 - 6.7e-40 137.2 0.1 3.7e-37 128.2 0.1 2.5 1 1 0 1 1 1 1 COG4 transport protein LuxT_C PF18285.1 PXF45393.1 - 0.06 13.9 0.0 0.3 11.7 0.0 2.3 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain Proteasome PF00227.26 PXF45394.1 - 2.6e-44 151.0 0.2 3.7e-44 150.5 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 PXF45394.1 - 0.033 13.6 0.5 0.033 13.6 0.5 1.7 2 0 0 2 2 2 0 Proteasome beta subunits C terminal Peptidase_M20 PF01546.28 PXF45395.1 - 2.8e-29 102.3 0.1 3.3e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 PXF45395.1 - 0.00046 19.9 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 PXF45395.1 - 0.0026 17.7 0.0 0.011 15.7 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain FtsJ PF01728.19 PXF45396.1 - 2e-37 129.0 0.0 2.2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Shal-type PF11601.8 PXF45396.1 - 0.18 11.4 0.3 0.33 10.5 0.3 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Spb1_C PF07780.12 PXF45397.1 - 8.9e-41 139.9 24.5 8.9e-41 139.9 24.5 3.5 3 2 2 5 5 5 1 Spb1 C-terminal domain DUF3381 PF11861.8 PXF45397.1 - 2.2e-36 125.1 12.4 2.2e-36 125.1 12.4 5.9 3 2 3 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.19 PXF45397.1 - 0.00061 20.0 0.1 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase FAM104 PF15434.6 PXF45399.1 - 0.061 13.9 1.6 0.12 13.0 1.6 1.5 1 0 0 1 1 1 0 Family 104 Uricase PF01014.18 PXF45400.1 - 1.1e-21 77.5 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Uricase DUF483 PF04467.12 PXF45400.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Bromodomain PF00439.25 PXF45401.1 - 1.7e-16 60.0 0.1 3.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Chol_subst-bind PF09129.11 PXF45401.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Mpv17_PMP22 PF04117.12 PXF45402.1 - 2.8e-20 72.3 0.1 2.8e-20 72.3 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family AAA_28 PF13521.6 PXF45403.1 - 9.9e-23 81.2 0.2 1.6e-22 80.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PXF45403.1 - 0.07 12.8 0.2 1 9.0 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase Maf PF02545.14 PXF45404.1 - 4.6e-28 98.1 0.0 5.2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DZR PF12773.7 PXF45405.1 - 0.054 13.5 2.7 0.11 12.5 2.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cupin_4 PF08007.12 PXF45406.1 - 3.7e-05 23.3 0.1 0.00012 21.6 0.0 1.9 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 PXF45406.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.22 PXF45406.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Cupin Pyrophosphatase PF00719.19 PXF45408.1 - 5.8e-46 156.2 0.0 7.5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Serine_rich PF08824.10 PXF45409.1 - 0.0039 17.2 0.4 0.0077 16.2 0.4 1.5 1 0 0 1 1 1 1 Serine rich protein interaction domain DUF4088 PF13317.6 PXF45409.1 - 0.17 11.4 1.4 0.67 9.5 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4088) DUF5082 PF16888.5 PXF45409.1 - 1.1 9.5 7.7 0.17 12.2 1.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Kelch_6 PF13964.6 PXF45410.1 - 1.1e-33 114.4 11.0 7e-07 29.3 0.0 7.4 5 2 2 7 7 7 6 Kelch motif Hint PF01079.20 PXF45410.1 - 5.1e-28 98.1 0.5 7.9e-28 97.4 0.5 1.2 1 0 0 1 1 1 1 Hint module Kelch_1 PF01344.25 PXF45410.1 - 5.4e-24 83.5 19.4 6.6e-08 32.0 0.1 6.8 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PXF45410.1 - 2e-17 62.9 17.7 3.6e-06 26.9 0.1 6.5 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF45410.1 - 9.3e-16 57.7 13.9 0.0054 17.0 0.2 7.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PXF45410.1 - 2.3e-15 55.8 13.4 0.00018 21.4 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PXF45410.1 - 1.4e-11 44.1 7.3 0.28 11.2 0.0 5.9 5 0 0 5 5 5 5 Kelch motif PQQ_3 PF13570.6 PXF45410.1 - 0.032 14.7 7.8 17 6.1 1.3 4.8 4 0 0 4 4 4 0 PQQ-like domain PT-HINT PF07591.11 PXF45410.1 - 0.035 14.3 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Glyoxal_oxid_N PF07250.11 PXF45410.1 - 0.047 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus SOG2 PF10428.9 PXF45410.1 - 1 8.5 5.6 1.3 8.1 5.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 PXF45410.1 - 9.6 6.0 7.7 13 5.5 7.7 1.2 1 0 0 1 1 1 0 SPX domain Spond_N PF06468.13 PXF45411.1 - 3.1e-19 69.8 0.0 3.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Spondin_N DUF1180 PF06679.12 PXF45411.1 - 0.17 12.3 0.3 0.9 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Lipase_3 PF01764.25 PXF45413.1 - 5.6e-26 91.1 0.0 9.3e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PXF45413.1 - 0.002 18.8 0.1 0.0053 17.4 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 PXF45413.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 PXF45413.1 - 0.0049 16.4 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 PXF45413.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MIG-14_Wnt-bd PF06664.12 PXF45413.1 - 0.11 11.7 37.6 0.4 9.8 33.0 2.8 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion CbiG_N PF11760.8 PXF45413.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal CaiF_GrlA PF07180.11 PXF45413.1 - 0.18 11.8 0.0 16 5.4 0.0 2.5 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator Tetraspanin PF00335.20 PXF45413.1 - 1.1 9.0 4.0 3.4 7.3 4.0 1.9 1 0 0 1 1 1 0 Tetraspanin family Claudin_2 PF13903.6 PXF45414.1 - 1.8e-11 44.2 11.4 2.6e-11 43.7 11.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PXF45414.1 - 5e-10 39.5 11.7 3.5e-06 27.0 9.8 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family Clc-like PF07062.12 PXF45414.1 - 0.00029 20.4 14.1 0.021 14.3 10.4 2.4 2 1 0 2 2 2 2 Clc-like Claudin_3 PF06653.11 PXF45414.1 - 0.0011 19.0 15.5 0.23 11.4 12.3 2.4 2 1 0 2 2 2 2 Tight junction protein, Claudin-like DUF2428 PF10350.9 PXF45414.1 - 0.027 13.7 0.4 0.049 12.9 0.4 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Amastin PF07344.11 PXF45414.1 - 0.55 10.1 17.5 0.6 9.9 11.3 2.7 1 1 1 3 3 3 0 Amastin surface glycoprotein DUF872 PF05915.12 PXF45414.1 - 0.59 10.3 5.1 0.17 12.0 0.9 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 PXF45414.1 - 0.95 9.8 14.2 2.7 8.3 6.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) FtsX PF02687.21 PXF45414.1 - 2 8.9 19.4 30 5.2 14.9 3.1 2 1 0 2 2 2 0 FtsX-like permease family DUF296 PF03479.15 PXF45416.1 - 0.12 12.7 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain Abhydrolase_1 PF00561.20 PXF45418.1 - 1.2e-19 71.0 0.0 1.1e-15 58.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF45418.1 - 4.4e-16 60.1 0.0 5.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF45418.1 - 1.2e-09 37.9 0.0 7.8e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 PXF45418.1 - 0.004 16.8 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 PXF45418.1 - 0.0097 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DLH PF01738.18 PXF45418.1 - 0.1 12.2 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family UEV PF05743.13 PXF45419.1 - 1.9e-30 105.2 0.6 2.9e-30 104.6 0.6 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 PXF45419.1 - 3.6e-19 68.5 0.4 8.8e-19 67.2 0.4 1.7 1 0 0 1 1 1 1 Vps23 core domain MTCP1 PF08991.10 PXF45419.1 - 0.13 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Glyoxalase PF00903.25 PXF45420.1 - 0.00047 20.3 0.0 0.00096 19.3 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF45420.1 - 0.006 16.8 0.0 0.0078 16.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Exo_endo_phos PF03372.23 PXF45421.1 - 4.2e-07 29.7 0.0 2e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5466 PF17554.2 PXF45422.1 - 1.4 9.2 4.3 1.4 9.1 2.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5466) Kelch_4 PF13418.6 PXF45423.1 - 3.7e-09 36.4 5.9 0.0044 17.0 0.0 4.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF45423.1 - 6.3e-09 35.9 10.2 0.22 11.9 0.1 6.8 6 1 0 6 6 6 3 Galactose oxidase, central domain Cytochrom_B561 PF03188.16 PXF45423.1 - 0.00017 21.8 7.8 0.00017 21.8 7.8 2.0 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Kelch_6 PF13964.6 PXF45423.1 - 0.00077 19.7 1.2 12 6.3 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Peroxin-3 PF04882.12 PXF45425.1 - 1e-15 57.7 10.2 3.1e-07 29.8 0.7 3.2 1 1 1 3 3 3 3 Peroxin-3 DUF1878 PF08963.10 PXF45425.1 - 0.036 14.6 0.1 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) KH_1 PF00013.29 PXF45426.1 - 1.8e-47 159.0 4.7 1.4e-16 60.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 PXF45426.1 - 8.8e-11 41.5 1.8 0.011 15.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PXF45426.1 - 1.3e-10 40.9 0.1 0.00066 19.5 0.0 3.5 3 0 0 3 3 3 3 KH domain SLS PF14611.6 PXF45426.1 - 0.0011 18.9 0.4 3.8 7.3 0.0 3.7 1 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 PXF45426.1 - 1.6 8.9 6.1 9.1 6.5 0.5 3.2 3 0 0 3 3 3 0 NusA-like KH domain adh_short PF00106.25 PXF45427.1 - 6.7e-34 117.1 0.1 9.5e-34 116.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF45427.1 - 1.1e-27 97.2 0.1 1.3e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 PXF45427.1 - 4.4e-06 26.0 0.0 2e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 PXF45427.1 - 5.9e-05 23.0 0.2 8.8e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF45427.1 - 0.0016 18.0 0.2 0.013 14.9 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family VWA_2 PF13519.6 PXF45427.1 - 0.015 15.9 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain 3Beta_HSD PF01073.19 PXF45427.1 - 0.041 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCHC PF00098.23 PXF45428.1 - 2.1e-16 59.2 36.9 0.00024 21.0 3.6 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 PXF45428.1 - 0.00012 21.8 38.0 0.03 14.2 1.6 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 PXF45428.1 - 0.0047 16.6 31.7 0.97 9.2 1.6 5.3 4 1 1 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 PXF45428.1 - 0.078 13.0 0.9 0.078 13.0 0.9 5.0 3 1 1 4 4 4 0 Zinc knuckle Copper-fist PF00649.18 PXF45428.1 - 4.9 6.7 22.9 1.6 8.3 1.6 4.1 2 1 2 4 4 4 0 Copper fist DNA binding domain Radical_SAM_C PF16199.5 PXF45429.1 - 1.3e-33 114.9 0.0 2.6e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 PXF45429.1 - 2.5e-21 76.8 0.3 2e-20 73.8 0.1 2.4 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 PXF45429.1 - 9.3e-10 38.8 0.1 1.7e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF45429.1 - 0.00011 22.2 0.1 0.00023 21.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF45429.1 - 0.0077 16.6 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF45429.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cmc1 PF08583.10 PXF45430.1 - 0.011 15.7 2.1 2.1 8.4 0.3 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Lustrin_cystein PF14625.6 PXF45430.1 - 0.27 11.7 3.5 1.9 8.9 0.4 2.5 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain MPLKIP PF15502.6 PXF45431.1 - 0.0005 20.2 0.0 0.00088 19.4 0.0 1.6 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Helicase_C PF00271.31 PXF45432.1 - 2.4e-09 37.5 0.0 6.9e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_1 PF00170.21 PXF45433.1 - 1.2e-05 25.3 3.0 1.2e-05 25.3 3.0 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF45433.1 - 0.00081 19.4 4.3 0.0015 18.5 4.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Csm1_N PF18504.1 PXF45433.1 - 0.052 13.9 1.9 0.052 13.9 1.9 1.9 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4773 PF15998.5 PXF45433.1 - 0.097 13.2 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4773) CCDC-167 PF15188.6 PXF45433.1 - 0.17 12.3 3.5 0.41 11.0 3.5 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Rubis-subs-bind PF09273.11 PXF45436.1 - 3e-23 82.9 0.3 6.2e-23 81.9 0.3 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PXF45436.1 - 3.8e-17 63.2 0.0 1.7e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 SET domain CLP_protease PF00574.23 PXF45437.1 - 2.4e-78 262.2 0.0 3e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease FMO-like PF00743.19 PXF45438.1 - 1.1e-46 159.3 0.1 1e-42 146.3 0.1 2.3 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PXF45438.1 - 1.9e-25 89.7 0.0 9e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF45438.1 - 1e-11 44.7 0.0 2.9e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PXF45438.1 - 9.7e-09 35.3 0.1 6.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PXF45438.1 - 1.6e-08 33.7 0.2 0.00095 18.0 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 PXF45438.1 - 3.7e-08 33.8 0.0 0.0057 17.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF45438.1 - 5.1e-07 29.6 1.0 0.016 14.8 0.2 3.3 2 1 2 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 PXF45438.1 - 2e-06 27.2 0.0 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 PXF45438.1 - 3e-06 27.3 1.7 9e-05 22.5 0.1 3.4 2 2 1 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 PXF45438.1 - 1.1e-05 25.0 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 PXF45438.1 - 7.8e-05 22.1 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 PXF45438.1 - 0.00031 20.0 0.9 0.00074 18.8 0.1 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 PXF45438.1 - 0.00064 18.9 0.1 0.081 12.0 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 PXF45438.1 - 0.0071 15.7 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 PXF45438.1 - 0.01 15.2 0.3 0.017 14.5 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PXF45438.1 - 0.017 15.5 0.0 9.9 6.7 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 PXF45438.1 - 0.067 12.7 0.0 10 5.5 0.0 2.9 3 1 0 3 3 3 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 PXF45438.1 - 0.19 11.8 0.0 12 6.0 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase DUF1534 PF07551.11 PXF45439.1 - 0.28 11.0 2.2 2 8.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) Plant_tran PF04827.14 PXF45440.1 - 6.8e-14 51.9 0.1 8.7e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Plant transposon protein WXG100 PF06013.12 PXF45443.1 - 0.0063 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF45443.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Vps53_N PF04100.12 PXF45444.1 - 7.5e-31 107.4 0.0 1.8e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 PXF45444.1 - 1.2e-13 50.3 1.3 2.2e-13 49.5 0.2 1.9 3 0 0 3 3 3 1 Exocyst complex component Sec6 VPS53_C PF16854.5 PXF45444.1 - 0.00017 21.5 0.1 0.00041 20.3 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus RINT1_TIP1 PF04437.13 PXF45444.1 - 0.0002 20.4 0.4 0.0021 17.0 0.4 2.2 1 1 0 1 1 1 1 RINT-1 / TIP-1 family COG2 PF06148.11 PXF45444.1 - 0.00028 21.0 3.6 0.0006 19.9 0.1 3.2 4 1 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 PXF45444.1 - 0.0016 18.6 1.6 0.0016 18.6 1.6 4.1 4 1 1 5 5 5 1 Golgi transport complex subunit 5 PRP1_N PF06424.12 PXF45444.1 - 0.022 15.1 0.1 0.068 13.6 0.1 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CK2S PF15011.6 PXF45444.1 - 0.034 14.0 2.1 0.099 12.5 0.6 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate RHD3 PF05879.12 PXF45444.1 - 0.12 10.5 2.1 0.13 10.4 0.7 1.6 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Cytochrom_B562 PF07361.11 PXF45444.1 - 0.41 11.3 2.2 1.8 9.3 1.4 2.5 2 0 0 2 2 2 0 Cytochrome b562 DUF4164 PF13747.6 PXF45444.1 - 1.2 9.4 4.9 0.89 9.9 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) PS_Dcarbxylase PF02666.15 PXF45445.1 - 2e-42 145.0 0.0 2.6e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PYNP_C PF07831.13 PXF45445.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Alg6_Alg8 PF03155.15 PXF45446.1 - 2.2e-116 389.7 20.4 3.2e-116 389.2 20.4 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family FeoB_associated PF12669.7 PXF45446.1 - 0.81 10.1 3.2 0.9 10.0 0.3 2.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Ribophorin_I PF04597.14 PXF45447.1 - 7.3e-91 305.6 0.0 8.4e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I VPS9 PF02204.18 PXF45449.1 - 0.06 13.6 0.1 0.086 13.1 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain Glyco_transf_22 PF03901.17 PXF45453.1 - 4.9e-77 259.9 28.0 6.1e-77 259.6 28.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_38 PF18438.1 PXF45453.1 - 0.14 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Abhydrolase_6 PF12697.7 PXF45454.1 - 1.4e-10 42.2 0.0 2.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF45454.1 - 4.9e-10 39.5 0.0 1.4e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF45454.1 - 3e-06 26.7 0.0 1.2e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF4389 PF14333.6 PXF45454.1 - 0.33 10.9 6.8 6.9 6.7 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) zf-RING_2 PF13639.6 PXF45455.1 - 2.9e-12 46.7 4.4 5.3e-12 45.9 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF45455.1 - 3.6e-10 39.5 4.6 5.9e-10 38.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF45455.1 - 1.6e-08 34.7 6.0 6.4e-08 32.8 6.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF45455.1 - 7.4e-07 28.9 3.1 1.1e-06 28.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF45455.1 - 3.8e-06 26.5 2.1 8.2e-06 25.5 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING-like PF08746.11 PXF45455.1 - 0.00049 20.4 3.0 0.00049 20.4 3.0 2.0 2 0 0 2 2 2 1 RING-like domain zf-C3HC4_3 PF13920.6 PXF45455.1 - 0.00097 18.9 6.0 0.00097 18.9 6.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF45455.1 - 0.0023 17.8 5.5 0.004 17.1 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PXF45455.1 - 0.012 15.6 5.9 0.026 14.5 5.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PXF45455.1 - 0.032 14.1 6.6 0.058 13.3 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PXF45455.1 - 0.053 13.1 4.6 0.078 12.6 4.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PXF45455.1 - 0.21 11.5 9.1 0.044 13.7 5.7 1.6 2 0 0 2 2 2 0 PHD-finger FANCL_C PF11793.8 PXF45455.1 - 0.59 10.4 9.1 0.65 10.2 3.8 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain ThiF PF00899.21 PXF45456.1 - 1.1e-25 90.4 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 PXF45457.1 - 8.9e-91 304.3 0.4 1.3e-90 303.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 PXF45457.1 - 2.2e-73 246.6 0.0 8.6e-70 234.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_UFD PF09358.10 PXF45457.1 - 4.6e-31 107.4 0.0 9.5e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 PXF45457.1 - 1.5e-14 53.9 0.0 4.9e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 PXF45457.1 - 5e-12 45.9 0.0 1.3e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Complex1_LYR_2 PF13233.6 PXF45457.1 - 0.055 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Complex1_LYR-like PBS_linker_poly PF00427.21 PXF45458.1 - 3.5e-33 114.3 0.1 5.3e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Phycobilisome Linker polypeptide CsgE PF10627.9 PXF45458.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Curli assembly protein CsgE FemAB_like PF04339.12 PXF45459.1 - 7e-118 394.0 4.7 8.8e-61 206.1 0.5 2.0 1 1 0 2 2 2 2 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 PXF45459.1 - 4.2e-11 43.2 0.7 1e-10 41.9 0.7 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EIF_2_alpha PF07541.12 PXF45460.1 - 1.1e-38 131.8 0.0 9.9e-38 128.8 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 PXF45460.1 - 3.8e-12 46.4 0.3 8.4e-12 45.3 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF835 PF05763.12 PXF45460.1 - 0.049 13.4 0.3 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF835) PsbP PF01789.16 PXF45461.1 - 9.3e-24 84.3 2.1 1.1e-23 84.1 2.1 1.1 1 0 0 1 1 1 1 PsbP DDE_1 PF03184.19 PXF45462.1 - 5.1e-32 110.9 0.1 2.8e-31 108.5 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF45462.1 - 3.4e-11 43.0 2.0 1.7e-09 37.5 0.2 2.9 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 PXF45462.1 - 0.00021 20.9 0.4 0.00021 20.9 0.4 2.3 2 1 1 3 3 3 1 Fission yeast centromere protein N-terminal domain HTH_9 PF08221.11 PXF45463.1 - 0.052 13.7 0.1 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF1843 PF08898.10 PXF45464.1 - 0.049 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) HEAT_2 PF13646.6 PXF45464.1 - 0.42 11.0 2.9 1.9 8.9 0.5 3.0 2 1 0 2 2 2 0 HEAT repeats Ribophorin_I PF04597.14 PXF45465.1 - 5.9e-70 236.6 0.0 6.8e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Rhabdo_glycop PF00974.18 PXF45465.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein tRNA-synt_1 PF00133.22 PXF45466.1 - 3.5e-37 128.0 0.0 3.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF45466.1 - 9.2e-08 31.2 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF45467.1 - 2.5e-40 138.4 0.0 2.8e-38 131.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 PXF45467.1 - 5.4e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 BRCT PF00533.26 PXF45468.1 - 0.01 16.2 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Neur_chan_memb PF02932.16 PXF45471.1 - 0.69 9.9 4.3 0.85 9.6 4.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Myb_DNA-binding PF00249.31 PXF45473.1 - 6.3e-12 45.5 1.9 1e-11 44.9 1.9 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF45473.1 - 0.0005 20.3 0.7 0.0014 18.8 0.8 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF45473.1 - 0.008 16.0 0.3 0.016 15.1 0.3 1.5 1 0 0 1 1 1 1 Myb DNA-binding like DUF4179 PF13786.6 PXF45473.1 - 0.043 14.3 0.0 12 6.4 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) UPF0565 PF10561.9 PXF45473.1 - 0.11 11.6 0.8 0.22 10.7 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Myb_DNA-bind_3 PF12776.7 PXF45473.1 - 0.2 12.7 2.3 0.51 11.3 0.5 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_60s PF00428.19 PXF45473.1 - 0.84 10.3 10.5 0.072 13.7 2.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein YabA PF06156.13 PXF45473.1 - 1.2 9.8 3.7 0.43 11.2 0.8 1.7 2 0 0 2 2 2 0 Initiation control protein YabA UPF0051 PF01458.17 PXF45474.1 - 3.6e-58 196.8 0.2 4.7e-58 196.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) TP6A_N PF04406.14 PXF45475.1 - 6.5e-20 70.9 0.1 1.2e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Myb_DNA-bind_7 PF15963.5 PXF45476.1 - 0.0075 16.1 1.2 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Myb DNA-binding like ELM2 PF01448.24 PXF45476.1 - 0.013 16.3 2.1 0.018 15.8 0.0 2.3 2 0 0 2 2 2 0 ELM2 domain Pkinase PF00069.25 PXF45477.1 - 5.7e-40 137.4 0.0 9.8e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45477.1 - 2.5e-18 66.3 0.0 7.7e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 PXF45477.1 - 1.1e-16 61.1 0.8 2.6e-12 47.0 0.3 2.6 2 0 0 2 2 2 2 Ribonuclease 2-5A PQQ_2 PF13360.6 PXF45477.1 - 4.7e-06 26.3 0.5 0.00021 21.0 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain Pkinase_fungal PF17667.1 PXF45477.1 - 2.3e-05 23.4 0.6 7e-05 21.8 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase PQQ PF01011.21 PXF45477.1 - 0.00056 19.7 0.1 1.3 9.0 0.0 3.8 4 0 0 4 4 4 1 PQQ enzyme repeat APH PF01636.23 PXF45477.1 - 0.00074 19.5 4.1 0.058 13.3 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF45477.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PXF45477.1 - 0.04 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PQQ_3 PF13570.6 PXF45477.1 - 0.13 12.8 0.0 33 5.1 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Aminotran_5 PF00266.19 PXF45478.1 - 5e-145 483.1 0.1 5.8e-145 482.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PXF45478.1 - 0.00051 19.5 1.0 0.0014 18.0 0.8 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF45478.1 - 0.005 15.4 0.2 0.0083 14.7 0.2 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.16 PXF45478.1 - 0.036 12.9 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SIS_2 PF13580.6 PXF45478.1 - 0.11 12.6 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 SIS domain Peptidase_M24 PF00557.24 PXF45479.1 - 1.5e-14 54.2 0.9 2.4e-14 53.5 0.9 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 KH_1 PF00013.29 PXF45480.1 - 3.4e-51 170.9 10.3 4.3e-15 55.3 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 PXF45480.1 - 5.6e-15 54.9 1.5 0.00024 20.9 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PXF45480.1 - 4.7e-09 36.0 1.8 0.046 13.6 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 PXF45480.1 - 6.7e-05 22.8 0.0 1.2 9.2 0.0 3.5 3 0 0 3 3 3 2 KH-like RNA-binding domain MecA PF05389.12 PXF45480.1 - 0.23 11.1 3.0 6.4 6.3 1.0 2.5 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) KH_5 PF13184.6 PXF45480.1 - 0.34 11.0 5.6 4.6 7.4 0.3 3.4 3 0 0 3 3 3 0 NusA-like KH domain Pkinase PF00069.25 PXF45481.1 - 4e-63 213.3 0.0 5.8e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45481.1 - 2.4e-36 125.4 0.1 3.6e-36 124.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45481.1 - 4.3e-06 26.3 0.0 2e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF45481.1 - 3.6e-05 23.2 0.0 0.00012 21.5 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF45481.1 - 3.9e-05 22.6 0.0 0.00011 21.1 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 PXF45481.1 - 0.18 10.8 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nucleo_P87 PF07267.11 PXF45481.1 - 4.5 6.0 5.5 6.4 5.5 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nfu_N PF08712.11 PXF45482.1 - 2.1e-31 107.8 0.0 4.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 PXF45482.1 - 1.2e-26 92.6 0.1 1.8e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Amidohydro_2 PF04909.14 PXF45482.1 - 0.036 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase Rdx PF10262.9 PXF45483.1 - 8.8e-10 38.6 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Rdx family zf-BED PF02892.15 PXF45483.1 - 0.082 12.9 1.0 0.17 12.0 1.0 1.5 1 0 0 1 1 1 0 BED zinc finger Glyco_hydro_9 PF00759.19 PXF45483.1 - 1.3 8.4 5.0 0.64 9.4 1.7 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Ion_trans_2 PF07885.16 PXF45484.1 - 3.1e-27 94.4 20.6 6.1e-15 55.0 10.2 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 PXF45484.1 - 9.9e-08 31.5 2.7 2.2e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 PXF45484.1 - 3.9e-07 29.1 7.4 0.00085 18.7 0.0 4.3 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 PXF45484.1 - 6.8e-07 28.7 5.8 0.0047 16.7 0.0 4.4 4 1 1 5 5 4 2 EF-hand domain EF-hand_5 PF13202.6 PXF45484.1 - 1.9e-06 27.1 6.5 0.0034 16.8 0.0 3.7 3 1 1 4 4 4 2 EF hand EF-hand_7 PF13499.6 PXF45484.1 - 1.3e-05 25.5 7.4 2.1e-05 24.9 1.5 3.5 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 PXF45484.1 - 5.1e-05 23.0 1.5 0.17 11.8 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair Lig_chan PF00060.26 PXF45484.1 - 0.0093 15.8 9.0 8.9 6.1 9.0 2.6 1 1 0 1 1 1 1 Ligand-gated ion channel IRK PF01007.20 PXF45484.1 - 0.085 12.7 6.6 0.79 9.5 0.8 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2101 PF09874.9 PXF45484.1 - 0.13 12.0 7.9 2.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) FA_desaturase PF00487.24 PXF45484.1 - 0.22 11.3 0.1 0.56 10.0 0.0 1.7 2 0 0 2 2 2 0 Fatty acid desaturase LMBR1 PF04791.16 PXF45484.1 - 2.2 7.1 8.8 2.2 7.1 2.5 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein LON_substr_bdg PF02190.16 PXF45485.1 - 4.7e-22 78.9 0.0 9.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 PXF45485.1 - 2.9e-07 30.2 15.2 6.3e-07 29.1 15.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF45485.1 - 0.00015 21.6 12.9 0.00015 21.6 12.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PXF45485.1 - 0.00018 21.3 13.2 0.00033 20.4 13.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PXF45485.1 - 0.00019 21.5 14.1 0.00048 20.2 14.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PXF45485.1 - 0.00023 21.4 14.5 0.00023 21.4 14.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PXF45485.1 - 0.00024 20.9 15.4 0.00056 19.7 15.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 PXF45485.1 - 0.00032 20.8 8.3 0.00066 19.8 8.3 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 PXF45485.1 - 0.00065 19.5 14.2 0.00065 19.5 14.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF45485.1 - 0.001 19.0 10.6 0.0039 17.2 10.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF45485.1 - 0.016 15.5 10.0 0.051 13.9 10.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain U-box PF04564.15 PXF45485.1 - 0.026 14.7 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.6 PXF45485.1 - 0.13 12.0 9.0 0.32 10.8 9.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PXF45485.1 - 0.28 10.9 13.8 0.16 11.7 7.1 2.4 1 1 1 2 2 2 0 P-11 zinc finger Cse1 PF08506.10 PXF45486.1 - 2.8e-101 339.0 0.7 6.7e-101 337.8 0.0 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 PXF45486.1 - 5.5e-90 302.0 0.8 4.7e-89 298.9 0.0 2.6 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 PXF45486.1 - 7.9e-08 32.1 0.2 3.5e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PXF45486.1 - 8.5e-06 25.9 2.7 0.021 14.9 0.0 5.4 3 3 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 PXF45486.1 - 0.055 13.8 0.6 14 6.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 PXF45486.1 - 0.094 13.3 2.2 11 6.6 0.1 4.5 4 0 0 4 4 4 0 HEAT-like repeat MMS19_C PF12460.8 PXF45486.1 - 0.27 10.3 4.2 0.4 9.7 0.2 3.2 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal MutL_C PF08676.11 PXF45487.1 - 9.4e-27 93.6 0.2 3.7e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 PXF45487.1 - 8.7e-15 54.4 0.0 2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PXF45487.1 - 6.4e-08 32.5 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PXF45487.1 - 0.0025 18.3 0.0 0.007 16.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDP_Man_Dehyd PF16363.5 PXF45488.1 - 3.6e-57 194.2 0.0 7.8e-57 193.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF45488.1 - 9.2e-49 166.1 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PXF45488.1 - 3.2e-14 52.7 0.0 8.6e-09 34.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 PXF45488.1 - 5.8e-11 41.9 0.0 8.1e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PXF45488.1 - 4e-10 39.3 0.2 3.6e-06 26.3 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PXF45488.1 - 2.3e-07 30.2 0.0 3.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 PXF45488.1 - 0.00018 21.0 0.0 0.00061 19.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PXF45488.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Cucumopine_C PF18631.1 PXF45488.1 - 0.023 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain KH_6 PF15985.5 PXF45489.1 - 2.4e-09 37.4 0.0 5.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 PXF45489.1 - 8.5e-05 23.1 0.1 0.026 15.1 0.0 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 VPS28 PF03997.12 PXF45491.1 - 2.4e-41 141.5 0.0 2.9e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein FUSC PF04632.12 PXF45492.1 - 10 4.5 5.8 16 3.8 5.1 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family Glyco_transf_54 PF04666.13 PXF45493.1 - 3.6e-06 26.1 0.0 0.00062 18.7 0.0 2.2 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 PXF45493.1 - 0.0064 16.4 0.1 0.0098 15.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Sel1 PF08238.12 PXF45494.1 - 6e-25 87.1 5.2 0.00015 22.4 0.0 10.6 12 0 0 12 12 12 4 Sel1 repeat TPR_7 PF13176.6 PXF45494.1 - 3e-06 26.9 13.1 0.73 10.0 0.2 9.1 10 0 0 10 10 10 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 PXF45494.1 - 3.4e-06 26.6 0.6 10 5.9 0.0 6.0 6 0 0 6 6 6 2 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.6 PXF45494.1 - 3.7e-05 24.1 12.4 18 6.2 0.5 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45494.1 - 0.00018 22.1 20.0 0.29 12.1 0.2 8.7 6 4 4 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF45494.1 - 0.00056 20.4 14.6 2 9.0 0.2 7.0 6 2 1 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF45494.1 - 0.0023 18.5 16.5 2.5 8.8 0.1 6.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF45494.1 - 0.031 14.4 9.5 25 5.3 0.3 7.3 7 1 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF45494.1 - 0.35 11.1 4.8 3.8 7.8 0.3 4.2 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Transposase_21 PF02992.14 PXF45498.1 - 0.0025 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 AATF-Che1 PF13339.6 PXF45499.1 - 0.15 12.7 1.8 0.35 11.5 0.0 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor RNase_PH PF01138.21 PXF45500.1 - 1.6e-14 54.6 0.1 3.4e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF45500.1 - 4e-06 26.8 0.1 9.8e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PNPase PF03726.14 PXF45500.1 - 0.0017 18.8 0.3 0.0078 16.7 0.1 2.3 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4954 PF16314.5 PXF45501.1 - 0.00047 18.4 0.1 0.00068 17.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep PF00132.24 PXF45501.1 - 0.058 13.2 0.5 0.46 10.3 0.4 2.3 1 1 1 2 2 2 0 Bacterial transferase hexapeptide (six repeats) MRAP PF15183.6 PXF45502.1 - 0.054 13.5 0.2 0.082 12.9 0.2 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DNA_ligase_aden PF01653.18 PXF45503.1 - 3.1e-21 75.8 0.0 3.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_aden PF01653.18 PXF45504.1 - 3.1e-12 46.2 0.0 3.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF45504.1 - 0.00058 19.7 0.1 0.00078 19.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain TelA PF05816.11 PXF45505.1 - 0.00017 20.8 0.4 0.00021 20.5 0.4 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Nup88 PF10168.9 PXF45505.1 - 0.015 13.1 0.2 0.018 12.9 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore component COG2 PF06148.11 PXF45505.1 - 0.032 14.3 0.1 4 7.5 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cytochrom_B562 PF07361.11 PXF45505.1 - 0.038 14.7 2.7 2.6 8.7 0.2 2.3 1 1 1 2 2 2 0 Cytochrome b562 CK2S PF15011.6 PXF45505.1 - 0.04 13.8 0.1 0.072 13.0 0.1 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate IFT57 PF10498.9 PXF45505.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 EzrA PF06160.12 PXF45505.1 - 0.054 11.7 0.4 0.14 10.3 0.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 PXF45505.1 - 0.067 13.1 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Sec34-like family PhaP_Bmeg PF09602.10 PXF45505.1 - 0.068 13.1 0.5 0.5 10.3 0.1 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1664 PF07889.12 PXF45505.1 - 0.08 13.0 0.6 2.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HbrB PF08539.11 PXF45505.1 - 0.087 12.8 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 HbrB-like DUF4298 PF14131.6 PXF45505.1 - 0.095 12.7 0.2 4.5 7.3 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) bZIP_1 PF00170.21 PXF45506.1 - 0.042 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor Fungal_TACC PF12709.7 PXF45506.1 - 0.059 13.8 0.1 0.082 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1640 PF07798.11 PXF45506.1 - 0.069 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_2 PF07716.15 PXF45506.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper PMM PF03332.13 PXF45507.1 - 3.4e-17 63.0 0.1 4.5e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase B12-binding PF02310.19 PXF45507.1 - 0.036 14.1 0.0 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 B12 binding domain DUF5507 PF17612.2 PXF45507.1 - 0.098 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5507) DctP PF03480.13 PXF45510.1 - 0.049 13.0 0.1 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Dot_icm_IcmQ PF09475.10 PXF45510.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Cytokin_check_N PF10407.9 PXF45510.1 - 0.15 12.1 0.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Thiolase_C PF02803.18 PXF45511.1 - 2.1e-33 114.6 0.1 3e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 PXF45511.1 - 1.1e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ABC_membrane_2 PF06472.15 PXF45511.1 - 5.6e-05 22.7 0.0 7.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DNA_ligase_aden PF01653.18 PXF45514.1 - 3.1e-21 75.8 0.0 3.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_aden PF01653.18 PXF45515.1 - 2.8e-12 46.3 0.0 3.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF45515.1 - 0.00059 19.7 0.1 0.00078 19.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain TelA PF05816.11 PXF45516.1 - 0.00017 20.8 0.4 0.00021 20.5 0.4 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Nup88 PF10168.9 PXF45516.1 - 0.015 13.1 0.2 0.018 12.9 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore component COG2 PF06148.11 PXF45516.1 - 0.032 14.3 0.1 4 7.5 0.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cytochrom_B562 PF07361.11 PXF45516.1 - 0.038 14.7 2.7 2.6 8.7 0.2 2.3 1 1 1 2 2 2 0 Cytochrome b562 CK2S PF15011.6 PXF45516.1 - 0.04 13.8 0.1 0.072 13.0 0.1 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate IFT57 PF10498.9 PXF45516.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 EzrA PF06160.12 PXF45516.1 - 0.054 11.7 0.4 0.14 10.3 0.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 PXF45516.1 - 0.067 13.1 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Sec34-like family PhaP_Bmeg PF09602.10 PXF45516.1 - 0.068 13.1 0.5 0.5 10.3 0.1 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1664 PF07889.12 PXF45516.1 - 0.08 13.0 0.6 2.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HbrB PF08539.11 PXF45516.1 - 0.087 12.8 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 HbrB-like DUF4298 PF14131.6 PXF45516.1 - 0.095 12.7 0.2 4.5 7.3 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) RecG_N PF17190.4 PXF45519.1 - 0.026 15.2 1.4 0.043 14.5 1.1 1.5 1 1 0 1 1 1 0 RecG N-terminal helical domain COG2 PF06148.11 PXF45519.1 - 0.034 14.2 4.6 0.2 11.8 4.6 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 PXF45519.1 - 0.045 13.8 6.9 0.06 13.4 6.9 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AATF-Che1 PF13339.6 PXF45519.1 - 0.052 14.2 0.7 0.063 14.0 0.7 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Xpo1 PF08389.12 PXF45519.1 - 0.071 13.2 3.1 2.7 8.1 0.2 2.0 1 1 1 2 2 2 0 Exportin 1-like protein DUF16 PF01519.16 PXF45519.1 - 0.12 12.9 3.1 0.19 12.2 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 YabA PF06156.13 PXF45519.1 - 0.17 12.6 2.7 0.25 12.0 2.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Phage_GPO PF05929.11 PXF45519.1 - 0.17 11.5 2.3 0.19 11.3 2.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4168 PF13767.6 PXF45519.1 - 0.18 13.0 3.0 0.25 12.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) THOC7 PF05615.13 PXF45519.1 - 0.51 10.6 4.5 0.74 10.1 4.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF1664 PF07889.12 PXF45519.1 - 0.55 10.3 4.6 1.4 9.0 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3767 PF12597.8 PXF45521.1 - 0.0034 17.2 0.1 0.008 16.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DED PF01335.21 PXF45521.1 - 0.017 15.4 0.1 0.041 14.2 0.1 1.6 1 0 0 1 1 1 0 Death effector domain DUF1844 PF08899.11 PXF45521.1 - 0.074 13.3 0.5 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) peroxidase PF00141.23 PXF45522.1 - 1.5e-26 93.5 0.1 1.9e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 Peroxidase Zw10 PF06248.13 PXF45523.1 - 0.00042 19.0 3.6 0.00046 18.9 0.1 2.6 3 0 0 3 3 3 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 PXF45523.1 - 0.00097 18.9 0.1 0.005 16.6 0.0 2.1 1 1 1 2 2 2 1 Retrograde transport protein Dsl1 C terminal DASH_Duo1 PF08651.10 PXF45523.1 - 0.76 9.6 3.4 6.5 6.6 0.2 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 BK_channel_a PF03493.18 PXF45524.1 - 1.1e-12 47.9 0.0 2.6e-11 43.6 0.0 2.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PXF45524.1 - 1.3e-10 41.1 4.6 3.1e-10 39.9 4.6 1.6 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 PXF45524.1 - 1.2e-05 25.5 0.0 0.007 16.6 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 PXF45524.1 - 0.025 13.8 7.4 0.041 13.1 7.4 1.2 1 0 0 1 1 1 0 Ion transport protein CHGN PF05679.16 PXF45525.1 - 4.7e-50 170.9 0.1 6.4e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 PXF45525.1 - 0.00034 20.2 0.9 0.00063 19.3 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 PXF45525.1 - 0.051 13.2 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 Nucleoporin_N PF08801.11 PXF45526.1 - 2.3e-61 207.9 0.2 4e-61 207.1 0.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 PXF45526.1 - 3.2e-13 49.3 0.7 7.7e-13 48.0 0.1 1.9 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2833 PF11090.8 PXF45526.1 - 0.064 13.6 0.2 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) WD40 PF00400.32 PXF45527.1 - 1.7e-05 25.5 0.6 1.2 10.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45527.1 - 5e-05 23.5 0.0 0.044 14.1 0.0 3.1 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain EMP70 PF02990.16 PXF45528.1 - 3.9e-142 474.6 6.9 3.9e-142 474.6 6.9 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 AAA_23 PF13476.6 PXF45529.1 - 1.7e-26 94.0 4.1 1.7e-26 94.0 4.1 7.6 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.19 PXF45529.1 - 1.5e-09 37.6 26.9 8.5e-09 35.2 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PXF45529.1 - 3.1e-09 37.1 0.0 0.002 18.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 PXF45529.1 - 9.6e-06 25.8 0.0 2.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 PXF45529.1 - 0.00015 21.6 0.0 0.00015 21.6 0.0 5.3 1 1 4 5 5 5 2 AAA ATPase domain AAA_29 PF13555.6 PXF45529.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 PXF45529.1 - 0.0085 16.6 0.0 0.0085 16.6 0.0 6.5 4 2 0 4 4 4 1 ABC transporter HHH_8 PF14716.6 PXF45529.1 - 0.42 11.0 6.1 3.6 8.0 0.1 4.3 4 0 0 4 4 4 0 Helix-hairpin-helix domain AAA_16 PF13191.6 PXF45529.1 - 3.9 7.8 0.0 3.9 7.8 0.0 5.1 5 1 0 5 5 5 0 AAA ATPase domain CarD_CdnL_TRCF PF02559.16 PXF45529.1 - 6.2 7.6 11.5 2.1 9.1 0.4 4.9 4 0 0 4 4 4 0 CarD-like/TRCF domain zf-RING_2 PF13639.6 PXF45530.1 - 1.1e-09 38.4 5.8 1.7e-09 37.8 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF45530.1 - 3.2e-06 26.8 2.8 3.2e-06 26.8 2.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF45530.1 - 4.2e-06 26.9 4.0 1.1e-05 25.6 4.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF45530.1 - 4.3e-06 26.6 4.4 6.3e-06 26.1 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PXF45530.1 - 1.6e-05 24.7 4.0 2.7e-05 23.9 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF45530.1 - 4e-05 23.4 5.7 6.4e-05 22.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF45530.1 - 4.1e-05 23.5 2.1 6.1e-05 23.0 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PXF45530.1 - 0.0011 18.9 1.5 0.0011 18.9 1.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF45530.1 - 0.0016 18.3 5.3 0.0047 16.8 5.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 PXF45530.1 - 0.0091 16.3 2.6 0.016 15.5 2.6 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.6 PXF45530.1 - 0.11 12.3 5.6 0.35 10.7 5.5 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 PXF45530.1 - 0.18 11.7 2.8 0.33 10.9 2.8 1.5 1 0 0 1 1 1 0 PHD-finger YdjO PF14169.6 PXF45530.1 - 0.21 11.4 2.5 4.4 7.1 0.5 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO Prok-RING_4 PF14447.6 PXF45530.1 - 0.29 11.0 5.4 0.52 10.2 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PXF45530.1 - 2.2 8.5 4.9 40 4.5 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain bZIP_1 PF00170.21 PXF45531.1 - 8.1e-07 29.1 11.9 1.4e-06 28.3 11.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF45531.1 - 7.9e-05 22.7 17.2 0.00059 19.9 17.2 2.2 1 1 0 1 1 1 1 Basic region leucine zipper DUF4778 PF16008.5 PXF45531.1 - 0.13 12.3 4.1 0.2 11.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TPM_phosphatase PF04536.14 PXF45532.1 - 2.4e-18 66.5 0.0 4.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 PXF45532.1 - 1.1e-13 51.3 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 zf-RING_2 PF13639.6 PXF45532.1 - 3.1e-10 40.2 3.0 1.1e-07 32.0 0.7 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 PXF45532.1 - 1.2e-07 31.5 1.1 1.4e-06 28.1 1.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF45532.1 - 1.7e-07 31.4 2.0 2.8e-07 30.7 0.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PXF45532.1 - 1.6e-06 27.8 4.8 0.00019 21.1 0.1 3.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF45532.1 - 2.4e-06 27.3 3.0 6.5e-05 22.7 0.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF45532.1 - 2.8e-06 27.3 0.7 5.3e-06 26.4 0.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PXF45532.1 - 1.3e-05 25.1 6.1 0.032 14.2 0.0 3.6 3 0 0 3 3 3 2 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF45532.1 - 3.6e-05 23.5 1.8 0.0019 18.0 0.3 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PXF45532.1 - 0.0003 20.7 0.5 0.0003 20.7 0.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF45532.1 - 0.00048 19.9 0.3 0.00048 19.9 0.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PXF45532.1 - 0.0019 18.3 0.6 0.0019 18.3 0.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 PXF45532.1 - 0.0023 18.1 3.4 0.0053 16.9 1.3 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PXF45532.1 - 0.03 13.9 0.7 0.088 12.4 0.7 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pellino PF04710.14 PXF45532.1 - 0.04 12.6 0.5 0.1 11.3 0.1 1.7 1 1 1 2 2 2 0 Pellino Rad50_zn_hook PF04423.14 PXF45532.1 - 0.043 13.7 0.1 7.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_16 PF17034.5 PXF45532.1 - 0.051 13.8 1.5 0.16 12.2 1.5 1.8 1 1 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 PXF45532.1 - 0.061 13.4 0.6 0.061 13.4 0.6 1.9 2 0 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.6 PXF45532.1 - 0.17 11.8 3.6 0.99 9.4 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 NT-C2 PF10358.9 PXF45533.1 - 4.6e-09 36.1 0.3 7.7e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HALZ PF02183.18 PXF45533.1 - 0.0045 17.2 9.9 0.14 12.4 1.1 2.5 2 0 0 2 2 2 2 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 PXF45533.1 - 0.018 15.0 3.0 0.021 14.7 1.0 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain Uso1_p115_C PF04871.13 PXF45533.1 - 0.02 15.3 3.2 0.044 14.1 3.2 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 PXF45533.1 - 0.045 13.8 6.0 0.36 10.9 0.6 2.5 1 1 1 2 2 2 0 bZIP transcription factor PikAIV_N PF18605.1 PXF45533.1 - 0.55 9.9 11.7 0.23 11.1 1.6 3.5 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain YabA PF06156.13 PXF45533.1 - 1.6 9.4 4.8 17 6.1 4.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA JIP_LZII PF16471.5 PXF45533.1 - 4.2 7.6 10.6 0.69 10.1 0.7 2.7 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 PXF45533.1 - 4.2 7.6 11.8 0.6 10.3 5.8 2.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Sel1 PF08238.12 PXF45534.1 - 8e-24 83.5 1.0 6.1e-06 26.7 0.0 9.2 9 0 0 9 9 9 4 Sel1 repeat GRAM PF02893.20 PXF45534.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain TPR_16 PF13432.6 PXF45534.1 - 0.23 12.1 0.0 0.23 12.1 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45534.1 - 6.8 7.8 19.9 37 5.5 0.0 7.9 6 3 4 10 10 10 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 PXF45536.1 - 9.5e-07 29.0 0.1 0.012 15.9 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF45536.1 - 7.3e-06 26.6 1.5 0.44 11.5 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 PXF45536.1 - 0.0022 17.4 0.0 0.012 14.9 0.0 2.1 1 1 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 PXF45536.1 - 0.0034 17.0 3.7 0.75 9.3 0.1 2.7 1 1 0 2 2 2 2 PQQ-like domain DUF2209 PF09974.9 PXF45536.1 - 0.029 14.7 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) PQQ PF01011.21 PXF45536.1 - 0.03 14.2 0.1 17 5.6 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 PXF45536.1 - 0.97 10.0 11.5 13 6.4 0.7 5.1 6 1 0 6 6 6 0 PQQ-like domain MmgE_PrpD PF03972.14 PXF45538.1 - 7.4e-80 268.6 1.4 1e-79 268.2 1.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Chromo PF00385.24 PXF45539.1 - 2.5e-08 33.7 1.2 3.5e-08 33.2 1.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ArsA_ATPase PF02374.15 PXF45542.1 - 6.9e-42 143.7 0.2 7.4e-42 143.6 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase PHM7_cyt PF14703.6 PXF45542.1 - 0.023 15.0 0.1 0.046 14.0 0.0 1.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L12 PF00542.19 PXF45542.1 - 0.13 12.6 4.7 3.8 7.9 0.1 3.4 3 1 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain DUF883 PF05957.13 PXF45542.1 - 1.4 9.6 5.2 4.6 7.9 3.7 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb2_4 PF04566.13 PXF45543.1 - 9.5e-05 22.6 0.1 0.00022 21.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 FAD_binding_8 PF08022.12 PXF45544.1 - 3.8e-17 62.3 0.0 7.3e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PXF45544.1 - 4.8e-15 56.0 0.0 2.9e-07 30.7 0.0 3.4 2 2 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF45544.1 - 1.1e-11 45.0 14.2 3.7e-11 43.2 14.2 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 PXF45544.1 - 0.033 14.8 0.0 11 6.8 0.0 2.7 2 2 0 2 2 2 0 Oxidoreductase NAD-binding domain TPR_1 PF00515.28 PXF45545.1 - 1.5e-46 154.3 28.5 0.019 14.8 0.1 17.6 18 0 0 18 18 17 11 Tetratricopeptide repeat TPR_10 PF13374.6 PXF45545.1 - 4.6e-44 147.1 32.4 0.0009 19.0 0.1 13.2 13 0 0 13 13 13 11 Tetratricopeptide repeat TPR_7 PF13176.6 PXF45545.1 - 5.4e-43 141.9 10.4 0.045 13.8 0.0 13.6 13 0 0 13 13 13 11 Tetratricopeptide repeat SNAP PF14938.6 PXF45545.1 - 1.1e-35 123.5 15.3 1.8e-07 30.9 2.1 6.5 1 1 4 6 6 6 6 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 PXF45545.1 - 4.3e-35 119.9 15.1 0.018 15.3 0.0 13.1 9 4 4 13 13 13 10 Tetratricopeptide repeat Sel1 PF08238.12 PXF45545.1 - 2.5e-32 110.6 0.0 0.12 13.1 0.1 11.4 11 0 0 11 11 11 8 Sel1 repeat MIT PF04212.18 PXF45545.1 - 1.9e-31 107.9 10.7 0.33 11.0 0.0 12.7 13 0 0 13 13 13 10 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 PXF45545.1 - 8.8e-31 103.5 23.7 0.24 11.6 0.0 14.0 14 0 0 14 14 13 10 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45545.1 - 1.5e-30 102.8 31.8 0.065 13.5 0.1 13.3 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45545.1 - 1.2e-23 82.5 41.0 0.18 11.5 0.1 14.1 14 1 0 14 14 13 8 TPR repeat TPR_14 PF13428.6 PXF45545.1 - 4.8e-14 51.9 13.6 7.7 7.6 0.0 12.0 11 1 1 12 12 12 0 Tetratricopeptide repeat DUF1722 PF08349.11 PXF45545.1 - 5.9e-13 49.1 0.0 0.24 11.7 0.0 6.4 4 2 0 6 6 6 3 Protein of unknown function (DUF1722) 14-3-3 PF00244.20 PXF45545.1 - 2.8e-12 46.6 13.1 0.6 9.6 0.4 10.2 2 2 9 11 11 11 1 14-3-3 protein NSF PF02071.20 PXF45545.1 - 4.7e-10 38.3 32.7 45 5.5 0.1 11.9 11 0 0 11 11 11 0 Aromatic-di-Alanine (AdAR) repeat DUF4071 PF13281.6 PXF45545.1 - 2.5e-09 36.7 6.3 3.2 6.7 0.0 8.2 2 2 7 9 9 9 3 Domain of unknown function (DUF4071) DUF2225 PF09986.9 PXF45545.1 - 1.5e-08 34.6 13.0 0.48 10.1 0.4 6.2 1 1 4 6 6 6 3 Uncharacterized protein conserved in bacteria (DUF2225) SGTA_dimer PF16546.5 PXF45545.1 - 1.5e-08 34.2 11.3 19 5.1 0.0 10.9 7 3 6 13 13 12 0 Homodimerisation domain of SGTA Arfaptin PF06456.13 PXF45545.1 - 4e-06 26.6 0.1 35 3.9 0.0 7.5 1 1 10 11 11 11 0 Arfaptin-like domain Nup96 PF12110.8 PXF45545.1 - 6.5e-06 25.5 1.6 35 3.4 0.0 7.9 5 2 2 9 9 9 0 Nuclear protein 96 ANAPC3 PF12895.7 PXF45545.1 - 0.00015 21.9 13.1 36 4.7 0.1 9.4 11 0 0 11 11 10 0 Anaphase-promoting complex, cyclosome, subunit 3 MIB_HERC2 PF06701.13 PXF45545.1 - 0.00064 19.9 9.4 9 6.6 0.1 7.3 6 1 3 9 9 9 0 Mib_herc2 TTSSLRR PF12468.8 PXF45545.1 - 0.0041 17.3 5.7 43 4.5 0.0 5.2 5 0 0 5 5 5 0 Type III secretion system leucine rich repeat protein DUF3560 PF12083.8 PXF45545.1 - 0.0059 16.7 17.7 6.7 6.9 0.1 8.0 3 2 6 9 9 9 0 Domain of unknown function (DUF3560) Kelch_1 PF01344.25 PXF45545.1 - 0.0084 15.7 1.5 72 3.1 0.0 5.9 6 0 0 6 6 6 0 Kelch motif Sda PF08970.10 PXF45545.1 - 0.035 13.8 34.2 19 5.1 0.2 10.1 10 0 0 10 10 10 0 Sporulation inhibitor A YtzH PF14165.6 PXF45545.1 - 0.04 14.3 5.1 66 4.0 0.0 5.7 6 0 0 6 6 6 0 YtzH-like protein FtsA PF14450.6 PXF45545.1 - 0.079 13.4 2.5 1.1e+02 3.3 2.5 5.3 1 1 0 1 1 1 0 Cell division protein FtsA RPN6_C_helix PF18503.1 PXF45545.1 - 0.11 12.3 11.3 3.9e+02 0.9 0.0 8.6 10 0 0 10 10 10 0 26S proteasome subunit RPN6 C-terminal helix domain SapA PF02199.15 PXF45545.1 - 2.3 8.6 19.4 2.2e+02 2.3 0.0 9.8 12 0 0 12 12 12 0 Saposin A-type domain CHAT PF12770.7 PXF45546.1 - 2.7e-26 92.7 0.0 7.8e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 CHAT domain TPR_1 PF00515.28 PXF45546.1 - 1.3e-10 40.6 8.6 0.044 13.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PXF45546.1 - 1.8e-10 40.1 5.4 0.15 12.1 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF45546.1 - 1.2e-09 38.3 3.9 0.35 11.2 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.6 PXF45546.1 - 1.6e-08 34.3 1.6 0.00012 21.7 0.1 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 PXF45546.1 - 3.2e-08 33.5 0.5 0.37 10.9 0.0 3.9 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 PXF45546.1 - 3.3e-08 33.2 7.4 0.016 15.0 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 PXF45546.1 - 2.5e-07 31.1 0.4 0.19 12.4 0.0 4.1 4 0 0 4 4 3 2 Sel1 repeat TPR_2 PF07719.17 PXF45546.1 - 5.1e-07 29.3 9.2 0.73 10.1 0.1 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45546.1 - 6.8e-07 29.0 7.2 0.32 11.3 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45546.1 - 5.9e-06 25.9 7.0 0.66 9.7 0.1 4.4 3 1 0 3 3 3 3 TPR repeat 14-3-3 PF00244.20 PXF45546.1 - 0.00048 19.7 0.0 2 7.8 0.0 3.2 2 1 1 3 3 3 1 14-3-3 protein Macoilin PF09726.9 PXF45546.1 - 0.065 11.8 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Macoilin family ANAPC3 PF12895.7 PXF45546.1 - 0.19 11.9 3.6 9.7 6.5 0.3 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_C50 PF03568.17 PXF45546.1 - 0.38 9.8 1.0 0.73 8.9 0.4 1.7 2 0 0 2 2 2 0 Peptidase family C50 NSF PF02071.20 PXF45546.1 - 1.1 10.3 8.8 56 5.2 0.1 4.4 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat Sda PF08970.10 PXF45546.1 - 2 8.2 4.1 67 3.3 0.1 3.5 3 0 0 3 3 3 0 Sporulation inhibitor A FAD_binding_4 PF01565.23 PXF45549.1 - 2.9e-06 27.1 0.3 0.0071 16.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.14 PXF45549.1 - 0.013 15.4 0.6 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase Abhydrolase_1 PF00561.20 PXF45553.1 - 9.1e-23 81.2 0.0 2e-22 80.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF45553.1 - 1.6e-10 42.0 0.0 2.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF45553.1 - 0.00097 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 PXF45553.1 - 0.26 10.3 0.0 0.44 9.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) NAD_binding_10 PF13460.6 PXF45554.1 - 2.5e-37 128.6 0.0 2.8e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF45554.1 - 1.4e-11 44.4 0.1 2.2e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF45554.1 - 8e-11 41.8 0.1 1.1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF45554.1 - 9.2e-05 21.6 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PXF45554.1 - 0.00019 20.7 0.1 0.00023 20.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 PXF45554.1 - 0.00096 19.3 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 PXF45554.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_trans_4_4 PF13579.6 PXF45554.1 - 0.025 15.0 1.0 0.05 14.0 1.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.25 PXF45554.1 - 0.1 12.0 0.2 0.21 11.0 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Nanovirus_C8 PF05629.11 PXF45556.1 - 0.12 12.4 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Nanovirus component 8 (C8) protein Bromodomain PF00439.25 PXF45563.1 - 1.6e-10 40.9 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain T3SS_ATPase_C PF18269.1 PXF45566.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain CAP_N PF01213.19 PXF45567.1 - 0.0087 15.6 0.4 0.0094 15.5 0.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal THDPS_N_2 PF14805.6 PXF45567.1 - 0.034 14.4 0.2 0.044 14.0 0.2 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DHC PF09626.10 PXF45567.1 - 0.13 13.1 0.1 0.17 12.8 0.1 1.2 1 0 0 1 1 1 0 Dihaem cytochrome c UL21a PF17636.2 PXF45568.1 - 0.0053 16.7 0.7 0.01 15.8 0.7 1.4 1 0 0 1 1 1 1 Viral Unique Long protein 21a HHH_2 PF12826.7 PXF45570.1 - 4.1e-05 23.6 0.0 0.0017 18.4 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 PXF45570.1 - 0.12 12.8 1.5 0.3 11.5 0.1 2.4 3 0 0 3 3 3 0 IMS family HHH motif DNA_ligase_aden PF01653.18 PXF45571.1 - 8.9e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF45571.1 - 8.6e-10 38.4 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain FH2 PF02181.23 PXF45574.1 - 3.9e-57 194.1 3.6 4.9e-57 193.7 3.6 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3886 PF13025.6 PXF45574.1 - 0.0082 16.3 1.1 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3886) Peptidase_C12 PF01088.21 PXF45574.1 - 0.19 11.4 0.4 0.6 9.8 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 CK2S PF15011.6 PXF45574.1 - 0.53 10.1 4.7 0.21 11.5 2.0 1.6 2 0 0 2 2 2 0 Casein Kinase 2 substrate FadA PF09403.10 PXF45574.1 - 1 9.9 3.6 0.56 10.7 0.2 2.2 2 0 0 2 2 2 0 Adhesion protein FadA YabA PF06156.13 PXF45574.1 - 3.8 8.2 5.8 1.2 9.9 2.5 1.9 2 0 0 2 2 2 0 Initiation control protein YabA FAD_binding_4 PF01565.23 PXF45575.1 - 2.9e-24 85.4 0.1 5.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PXF45575.1 - 1.8e-13 50.3 0.2 4.8e-13 49.0 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF3421 PF11901.8 PXF45576.1 - 2.9e-38 130.4 4.5 1.2e-24 86.5 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) JmjC PF02373.22 PXF45577.1 - 6.8e-32 110.3 0.2 1.8e-31 108.9 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 PXF45577.1 - 0.013 15.4 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 jmjN domain DUF1923 PF09083.10 PXF45578.1 - 1.2e-06 28.2 7.8 18 5.1 0.0 7.9 8 0 0 8 8 8 4 Domain of unknown function (DUF1923) LEAP-2 PF07359.11 PXF45578.1 - 0.013 15.3 0.5 0.013 15.3 0.5 16.5 18 2 2 20 20 20 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DUF1923 PF09083.10 PXF45580.1 - 0.0001 22.0 1.0 12 5.7 0.0 5.1 5 0 0 5 5 5 3 Domain of unknown function (DUF1923) LEAP-2 PF07359.11 PXF45580.1 - 0.0078 16.0 0.4 0.0078 16.0 0.4 12.3 13 1 1 14 14 14 7 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Plant_tran PF04827.14 PXF45582.1 - 1.6e-18 67.0 0.0 1.8e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF45582.1 - 5.2e-05 23.0 0.0 5.6e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1923 PF09083.10 PXF45585.1 - 2.8e-05 23.7 1.3 12 5.7 0.0 5.3 5 0 0 5 5 5 3 Domain of unknown function (DUF1923) LEAP-2 PF07359.11 PXF45585.1 - 0.0078 16.0 0.4 0.0078 16.0 0.4 12.3 13 1 1 14 14 14 7 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Ephrin_rec_like PF07699.13 PXF45587.1 - 1.9e-09 37.1 62.8 0.0012 18.6 5.6 7.2 1 1 9 10 10 10 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 PXF45587.1 - 0.026 14.9 46.4 4.6 7.7 0.1 8.3 2 2 5 8 8 8 0 TNFR/NGFR cysteine-rich region AhpC-TSA PF00578.21 PXF45591.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Hint PF01079.20 PXF45592.1 - 2.4e-19 69.7 0.3 6.5e-19 68.3 0.3 1.6 1 1 0 1 1 1 1 Hint module Hom_end_hint PF05203.16 PXF45592.1 - 0.059 13.3 0.1 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Ndc80_HEC PF03801.13 PXF45593.1 - 2.2e-45 154.0 0.0 4.6e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 PXF45593.1 - 3e-11 43.2 0.1 3e-11 43.2 0.1 4.3 3 2 2 5 5 5 1 Domain of unknown function (DUF5595) CENP-F_leu_zip PF10473.9 PXF45593.1 - 2.8e-05 24.2 31.4 0.037 14.0 2.9 3.3 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 PXF45593.1 - 0.014 15.5 2.3 0.014 15.5 2.3 3.6 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Selenoprotein_S PF06936.11 PXF45593.1 - 0.18 11.6 4.6 0.56 10.0 4.6 1.9 1 0 0 1 1 1 0 Selenoprotein S (SelS) Tropomyosin_1 PF12718.7 PXF45593.1 - 2.8 8.1 31.2 0.11 12.6 0.5 3.7 2 2 2 4 4 4 0 Tropomyosin like DUF5471 PF17565.2 PXF45594.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5471) FlaC_arch PF05377.11 PXF45596.1 - 0.0071 16.7 0.2 0.012 16.0 0.2 1.3 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Taxilin PF09728.9 PXF45596.1 - 0.026 13.7 0.4 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein COG7 PF10191.9 PXF45596.1 - 0.037 12.3 0.1 0.041 12.1 0.1 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) WD40 PF00400.32 PXF45599.1 - 6e-15 55.4 1.9 0.001 19.8 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45599.1 - 0.0011 19.2 0.0 1.9 8.8 0.0 3.6 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PXF45599.1 - 0.043 12.5 0.4 7.8 5.1 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like DDE_Tnp_1 PF01609.21 PXF45600.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Methyltransf_25 PF13649.6 PXF45601.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.6 PXF45602.1 - 8.5e-11 41.9 0.1 2.7e-10 40.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PXF45602.1 - 1.3e-08 34.6 0.1 0.0019 17.6 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 PXF45602.1 - 7.5e-08 32.3 0.5 5.3e-07 29.5 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF45602.1 - 1.1e-06 28.0 0.2 0.00047 19.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 PXF45602.1 - 3.4e-05 22.7 0.0 0.089 11.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 PXF45602.1 - 0.0009 18.6 0.1 0.0023 17.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PXF45602.1 - 0.0017 17.7 0.2 0.0035 16.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PXF45602.1 - 0.0026 17.2 0.1 0.0041 16.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF45602.1 - 0.0032 16.8 0.1 0.0056 15.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase YlmH_RBD PF17774.1 PXF45603.1 - 1e-07 32.1 0.1 2.1e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Putative RNA-binding domain in YlmH S4 PF01479.25 PXF45603.1 - 0.0017 18.0 0.2 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 S4 domain HLH PF00010.26 PXF45604.1 - 5.7e-06 26.2 0.6 1.2e-05 25.2 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1577 PF07614.11 PXF45604.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) Glyco_hydro_9 PF00759.19 PXF45604.1 - 1.1 8.7 5.0 1.6 8.1 5.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF5427 PF10310.9 PXF45605.1 - 0.28 10.1 7.3 0.31 10.0 7.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MRI PF15325.6 PXF45605.1 - 0.37 11.9 5.0 0.24 12.5 3.3 1.5 1 1 1 2 2 2 0 Modulator of retrovirus infection NUMOD3 PF07460.11 PXF45606.1 - 4.4e-15 55.6 15.2 2.5e-10 40.4 0.3 3.8 4 0 0 4 4 4 3 NUMOD3 motif (2 copies) Carbpep_Y_N PF05388.11 PXF45606.1 - 0.08 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MEF2_binding PF09047.10 PXF45606.1 - 0.69 9.8 3.2 11 5.9 0.1 3.2 3 0 0 3 3 3 0 MEF2 binding Motile_Sperm PF00635.26 PXF45607.1 - 9.6e-21 73.7 0.8 1.9e-20 72.7 0.8 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain NAM-associated PF14303.6 PXF45607.1 - 0.088 13.5 2.9 0.21 12.3 2.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-C3H2C3 PF17122.5 PXF45608.1 - 8.2e-05 22.6 5.2 8.2e-05 22.6 5.2 2.8 3 0 0 3 3 3 1 Zinc-finger VPS11_C PF12451.8 PXF45608.1 - 8.9e-05 22.6 0.3 0.00022 21.4 0.3 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-HC5HC2H PF13771.6 PXF45608.1 - 0.029 14.6 0.1 0.099 12.9 0.1 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Mic1 PF07035.12 PXF45608.1 - 0.052 13.3 0.3 0.44 10.2 0.2 2.3 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like zf-RING_2 PF13639.6 PXF45608.1 - 0.069 13.5 3.3 0.26 11.6 3.3 2.1 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 PXF45608.1 - 0.083 12.9 1.3 0.23 11.5 1.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PXF45608.1 - 0.32 10.9 8.2 0.057 13.3 2.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF45608.1 - 3.1 7.7 5.4 0.92 9.4 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF45608.1 - 4.2 7.7 6.5 0.76 10.1 1.4 2.5 3 0 0 3 3 3 0 RING-H2 zinc finger domain Myb_DNA-binding PF00249.31 PXF45609.1 - 6.6e-23 80.6 2.2 1.6e-14 53.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF45609.1 - 7.3e-18 64.6 2.8 6e-10 39.2 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF45609.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Myb DNA-binding like DAO_C PF16901.5 PXF45610.1 - 7.5e-38 129.3 0.1 1.2e-37 128.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 PXF45610.1 - 1e-30 107.5 0.1 1.8e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF45610.1 - 0.00029 20.1 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PXF45610.1 - 0.036 13.3 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Tmemb_170 PF10190.9 PXF45615.1 - 7.3e-12 45.6 9.0 8.5e-12 45.4 9.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Spt20 PF12090.8 PXF45616.1 - 0.00012 21.8 1.1 0.00081 19.1 0.0 2.0 1 1 1 2 2 2 2 Spt20 family PALP PF00291.25 PXF45617.1 - 1.4e-35 123.2 0.0 1.6e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NUC153 PF08159.12 PXF45618.1 - 5.3e-09 35.7 3.0 1.2e-08 34.6 3.0 1.6 1 0 0 1 1 1 1 NUC153 domain Cytochrom_D1 PF02239.16 PXF45618.1 - 0.027 13.0 0.0 0.049 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40 PF00400.32 PXF45618.1 - 0.17 12.8 0.4 59 4.8 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF883 PF05957.13 PXF45619.1 - 0.023 15.3 1.0 0.042 14.4 0.8 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) H-kinase_dim PF02895.14 PXF45619.1 - 0.098 13.1 0.3 0.13 12.7 0.2 1.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain IL2 PF00715.17 PXF45619.1 - 0.1 12.5 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Interleukin 2 Cons_hypoth95 PF03602.15 PXF45619.1 - 0.13 11.9 0.1 0.15 11.7 0.1 1.0 1 0 0 1 1 1 0 Conserved hypothetical protein 95 VHP PF02209.19 PXF45620.1 - 0.00023 21.2 1.0 0.00051 20.1 1.0 1.6 1 0 0 1 1 1 1 Villin headpiece domain RIO1 PF01163.22 PXF45622.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PXF45622.1 - 0.042 13.8 0.0 0.15 12.0 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 PXF45624.1 - 5.3e-11 42.4 0.0 7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PXF45624.1 - 0.00017 21.0 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF45624.1 - 0.00042 20.3 0.4 0.0007 19.6 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF45624.1 - 0.0012 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PXF45624.1 - 0.0044 16.3 0.0 0.0058 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 PXF45627.1 - 2.2e-05 24.6 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain AATF-Che1 PF13339.6 PXF45627.1 - 0.0054 17.4 0.4 0.019 15.6 0.4 1.9 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor ZapB PF06005.12 PXF45627.1 - 3.2 8.3 5.4 3.7 8.1 1.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF3549 PF12069.8 PXF45629.1 - 0.066 12.2 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) CS PF04969.16 PXF45630.1 - 1.6e-12 48.3 0.2 2.9e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 CS domain GSH_synth_ATP PF03917.17 PXF45631.1 - 1.2e-107 360.0 0.0 1.4e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 PXF45631.1 - 1.3e-28 99.5 0.1 2.5e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase dsDNA_bind PF01984.20 PXF45632.1 - 3.4e-32 111.0 10.1 4.1e-32 110.7 10.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 PXF45632.1 - 0.69 10.4 0.2 0.69 10.4 0.2 3.2 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region GDI PF00996.18 PXF45634.1 - 2.7e-45 154.7 0.0 1.3e-34 119.5 0.0 2.3 2 1 0 2 2 2 2 GDP dissociation inhibitor GMP_synt_C PF00958.22 PXF45635.1 - 2.3e-43 146.1 0.0 4.3e-43 145.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 PXF45635.1 - 1.1e-41 142.7 0.0 2.3e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 PXF45635.1 - 9.8e-08 31.4 0.1 1.2e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 NAD synthase Peptidase_C26 PF07722.13 PXF45635.1 - 3.6e-07 30.2 0.2 3.6e-06 26.9 0.1 2.4 2 1 0 2 2 2 1 Peptidase C26 QueC PF06508.13 PXF45635.1 - 8.8e-05 22.1 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 PXF45635.1 - 0.00074 18.4 0.1 0.0014 17.5 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 PXF45635.1 - 0.0042 16.7 0.1 0.0088 15.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 PXF45635.1 - 0.0059 16.7 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 PXF45635.1 - 0.0075 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 PXF45635.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 PXF45635.1 - 0.022 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase zf-C3H1 PF10650.9 PXF45636.1 - 0.0001 22.0 0.7 0.00016 21.3 0.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain DUF2031 PF09592.10 PXF45636.1 - 0.038 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) FlxA PF14282.6 PXF45636.1 - 0.056 13.4 2.8 0.18 11.8 2.8 1.8 1 0 0 1 1 1 0 FlxA-like protein Atg14 PF10186.9 PXF45636.1 - 0.28 10.2 8.5 0.65 9.0 1.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bromodomain PF00439.25 PXF45637.1 - 1.4e-16 60.3 0.1 3.2e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PXF45637.1 - 6.9e-10 38.9 0.2 1.5e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation AAA_11 PF13086.6 PXF45637.1 - 4.8 6.9 15.0 11 5.7 15.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PXF45638.1 - 5.9e-66 222.5 0.2 1.4e-64 218.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45638.1 - 5e-36 124.3 0.0 2.6e-35 122.0 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45638.1 - 1.6e-06 27.7 0.0 1.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PXF45638.1 - 0.00037 20.5 0.4 0.21 11.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF45638.1 - 0.0032 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF45638.1 - 0.012 14.5 0.1 0.012 14.5 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 PXF45638.1 - 0.029 14.0 0.9 6.1 6.4 0.1 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PH PF00169.29 PXF45638.1 - 0.034 14.6 0.4 8.5 7.0 0.0 2.9 2 0 0 2 2 2 0 PH domain dbPDZ_assoc PF16610.5 PXF45638.1 - 2.6 8.3 9.9 0.73 10.1 4.6 2.8 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 bZIP_2 PF07716.15 PXF45639.1 - 6.6e-05 22.9 5.5 6.6e-05 22.9 5.5 2.4 2 1 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF45639.1 - 0.0005 20.1 15.0 0.026 14.6 15.0 2.4 1 1 0 1 1 1 1 bZIP transcription factor Ribosomal_L36e PF01158.18 PXF45639.1 - 0.012 15.8 0.4 0.026 14.8 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L36e Macoilin PF09726.9 PXF45639.1 - 0.025 13.2 4.4 0.031 12.8 4.4 1.0 1 0 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 PXF45639.1 - 9.4 6.8 14.4 1.4 9.5 9.6 2.1 2 1 0 2 2 2 0 bZIP Maf transcription factor zf-CHY PF05495.12 PXF45640.1 - 6.5e-13 49.0 17.9 6.5e-13 49.0 17.9 2.9 2 0 0 2 2 2 1 CHY zinc finger DUF1319 PF07028.11 PXF45640.1 - 0.14 12.3 0.6 0.3 11.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) RWP-RK PF02042.15 PXF45641.1 - 1.2e-21 76.4 1.7 1.7e-21 75.9 1.1 1.6 2 0 0 2 2 2 1 RWP-RK domain Serglycin PF04360.12 PXF45641.1 - 0.7 9.8 29.6 0.36 10.8 9.6 3.3 3 0 0 3 3 3 0 Serglycin XG_FTase PF03254.13 PXF45642.1 - 0.0046 15.6 0.0 0.0069 15.1 0.0 1.2 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase NodZ PF05830.11 PXF45642.1 - 0.019 13.8 0.8 2.6 6.8 0.0 2.5 3 0 0 3 3 3 0 Nodulation protein Z (NodZ) Fcf1 PF04900.12 PXF45642.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Fcf1 Aminotran_4 PF01063.19 PXF45643.1 - 6e-32 111.3 0.0 7.8e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV OmpH PF03938.14 PXF45644.1 - 0.0036 17.6 1.6 0.0054 17.1 1.6 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) YlbD_coat PF14071.6 PXF45644.1 - 0.0039 17.4 0.3 0.006 16.8 0.3 1.2 1 0 0 1 1 1 1 Putative coat protein Dynactin_p22 PF07426.11 PXF45644.1 - 0.042 13.7 0.8 0.13 12.1 0.8 1.8 1 1 1 2 2 2 0 Dynactin subunit p22 Noelin-1 PF12308.8 PXF45644.1 - 0.057 13.4 0.2 0.11 12.6 0.2 1.5 1 1 0 1 1 1 0 Neurogenesis glycoprotein ACP_PD PF04336.12 PXF45644.1 - 0.071 13.5 2.0 0.2 12.1 0.9 2.0 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase ARTD15_N PF18084.1 PXF45644.1 - 0.1 12.8 0.2 6.1 7.2 0.0 2.3 2 0 0 2 2 2 0 ARTD15 N-terminal domain Mito_carr PF00153.27 PXF45645.1 - 2.8e-46 155.4 5.3 6.3e-20 70.9 0.4 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein L_biotic_typeA PF04604.13 PXF45645.1 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Type-A lantibiotic Peptidase_U4 PF03419.13 PXF45645.1 - 0.094 12.0 0.1 13 4.9 0.0 2.5 3 0 0 3 3 3 0 Sporulation factor SpoIIGA PMSR PF01625.21 PXF45646.1 - 2.4e-55 186.9 1.0 4e-55 186.2 1.0 1.4 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Glutaredoxin PF00462.24 PXF45646.1 - 1e-29 102.5 0.5 1.6e-13 50.7 0.0 3.0 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin_2 PF13098.6 PXF45646.1 - 1.5e-05 25.4 0.0 0.32 11.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain DUF836 PF05768.14 PXF45646.1 - 3.2e-05 24.2 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 PXF45646.1 - 0.0016 18.4 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin DSBA PF01323.20 PXF45646.1 - 0.0089 15.8 3.4 0.45 10.3 0.1 3.4 3 1 0 4 4 4 1 DSBA-like thioredoxin domain DUF953 PF06110.11 PXF45646.1 - 0.017 14.8 0.1 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_4 PF13462.6 PXF45646.1 - 0.99 9.5 4.6 0.93 9.6 0.1 3.1 4 0 0 4 4 4 0 Thioredoxin Bromodomain PF00439.25 PXF45647.1 - 3.5e-14 52.6 0.0 1.3e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Bromodomain CAF1 PF04857.20 PXF45648.1 - 3.1e-49 167.9 0.0 2.1e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease SLY PF12485.8 PXF45648.1 - 0.013 16.3 2.0 0.023 15.4 2.0 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein zf-CCCH PF00642.24 PXF45648.1 - 0.039 13.9 0.8 0.064 13.2 0.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KASH_CCD PF14662.6 PXF45648.1 - 0.12 12.2 4.3 0.18 11.6 4.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Torus PF16131.5 PXF45648.1 - 0.2 12.3 1.5 0.32 11.7 0.1 2.0 1 1 0 1 1 1 0 Torus domain DUF4778 PF16008.5 PXF45648.1 - 0.53 10.3 4.5 0.75 9.8 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) PI3_PI4_kinase PF00454.27 PXF45649.1 - 7.8e-63 212.6 0.1 1.8e-62 211.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PXF45649.1 - 2.1e-52 178.5 0.0 4.6e-52 177.4 0.0 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 PXF45649.1 - 2e-30 105.1 0.6 2e-30 105.1 0.6 2.4 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 PXF45649.1 - 2.3e-22 79.6 2.0 1.9e-17 63.7 0.0 4.6 2 1 0 3 3 3 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 PXF45649.1 - 0.00018 21.8 18.5 0.00094 19.5 0.1 5.9 6 0 0 6 6 6 2 HEAT repeats RIX1 PF08167.12 PXF45649.1 - 0.061 13.0 1.4 0.23 11.2 0.3 2.6 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 PXF45649.1 - 1.3 9.6 11.7 18 6.0 0.2 6.1 5 0 0 5 5 5 0 HEAT-like repeat bZIP_2 PF07716.15 PXF45650.1 - 0.0057 16.7 12.2 0.014 15.4 12.3 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF45650.1 - 0.082 13.4 11.0 0.15 12.6 11.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 PXF45650.1 - 2.2 8.5 16.9 4.9 7.3 16.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor GCP_C_terminal PF04130.13 PXF45651.1 - 1.9e-56 191.8 15.1 3.3e-56 191.0 15.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PXF45651.1 - 4.7e-53 180.8 0.0 9e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal WD40 PF00400.32 PXF45652.1 - 0.0026 18.6 0.3 0.015 16.2 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_3 PF13570.6 PXF45652.1 - 0.033 14.7 0.5 18 5.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF4269 PF14091.6 PXF45652.1 - 0.88 9.8 6.8 0.58 10.4 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) AhpC-TSA_2 PF13911.6 PXF45653.1 - 1.6e-17 63.7 0.0 3.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PXF45653.1 - 6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF45653.1 - 0.043 13.5 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Redoxin CEP76-C2 PF15627.6 PXF45653.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CEP76 C2 domain adh_short PF00106.25 PXF45654.1 - 3.7e-38 131.0 6.7 4.9e-38 130.6 6.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF45654.1 - 2.2e-33 115.8 11.4 3.3e-33 115.2 11.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF45654.1 - 4e-13 49.7 7.3 9.4e-13 48.5 7.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF45654.1 - 3e-06 26.9 2.4 1.6e-05 24.5 1.9 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF45654.1 - 0.007 15.8 1.1 0.12 11.8 1.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase eIF-6 PF01912.18 PXF45654.1 - 0.061 12.7 0.4 0.09 12.2 0.4 1.2 1 0 0 1 1 1 0 eIF-6 family Hemerythrin PF01814.23 PXF45656.1 - 0.00099 19.7 0.0 0.0029 18.2 0.0 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain GTP-bdg_M PF16360.5 PXF45657.1 - 2.6e-30 104.8 5.9 2.6e-30 104.8 5.9 2.6 3 0 0 3 3 2 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 PXF45657.1 - 2.8e-28 98.4 0.5 7.9e-28 97.0 0.1 2.0 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 PXF45657.1 - 5.8e-20 71.5 0.3 1.5e-19 70.2 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF45657.1 - 3.8e-07 29.7 0.1 1e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PXF45657.1 - 4.5e-07 29.9 0.1 0.00073 19.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PXF45657.1 - 1.4e-05 25.2 0.1 9.6e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 PXF45657.1 - 0.00011 21.9 0.6 0.0029 17.2 0.5 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PXF45657.1 - 0.00019 21.0 0.0 0.00048 19.6 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 PXF45657.1 - 0.00033 20.3 5.0 0.0031 17.1 0.8 2.9 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 PXF45657.1 - 0.0067 15.9 0.7 0.18 11.2 0.0 2.6 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_16 PF13191.6 PXF45657.1 - 0.018 15.4 0.2 0.018 15.4 0.2 1.9 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 PXF45657.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 PXF45657.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1_Xtn PF16897.5 PXF45657.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_29 PF13555.6 PXF45657.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4079 PF13301.6 PXF45659.1 - 1.9e-39 135.0 3.3 2.9e-39 134.4 3.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 PXF45659.1 - 0.00016 21.3 2.8 0.00026 20.6 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 CPP1-like PF11833.8 PXF45659.1 - 0.032 13.9 0.3 0.059 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NUDIX PF00293.28 PXF45660.1 - 3e-06 27.3 0.9 1.1e-05 25.4 0.9 1.8 1 1 0 1 1 1 1 NUDIX domain DUF745 PF05335.13 PXF45660.1 - 0.21 11.3 0.0 0.68 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Pkinase PF00069.25 PXF45661.1 - 4.1e-69 232.9 0.0 5.8e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45661.1 - 4.2e-33 114.7 0.0 6.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45661.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PXF45661.1 - 0.0033 17.4 0.1 0.092 12.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF45661.1 - 0.075 12.4 0.1 0.38 10.1 0.1 2.1 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAP PF00188.26 PXF45662.1 - 0.023 15.6 0.7 0.023 15.6 0.7 2.4 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Aminotran_1_2 PF00155.21 PXF45664.1 - 1.4e-38 133.0 0.0 1.8e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PXF45664.1 - 6.2e-08 32.3 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF45664.1 - 0.0074 14.9 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 PXF45664.1 - 0.033 12.8 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Aminotran_5 PF00266.19 PXF45664.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Alliinase_C PF04864.13 PXF45664.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Allinase Beta_elim_lyase PF01212.21 PXF45664.1 - 0.22 10.7 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Pro_isomerase PF00160.21 PXF45665.1 - 1.1e-29 103.7 0.1 2.2e-29 102.8 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PEMT PF04191.13 PXF45666.1 - 9.3e-24 83.9 0.6 2.1e-23 82.7 0.6 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase RNB PF00773.19 PXF45667.1 - 1.1e-55 189.3 0.0 3.2e-44 151.6 0.0 2.3 1 1 1 2 2 2 2 RNB domain SH3_10 PF17902.1 PXF45667.1 - 0.059 13.4 0.1 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 SH3 domain Coprogen_oxidas PF01218.18 PXF45668.1 - 4.4e-91 304.7 0.0 5.1e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF2615 PF11027.8 PXF45668.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) UvrB PF12344.8 PXF45670.1 - 4.6e-15 55.2 0.1 1.1e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 PXF45670.1 - 3.7e-11 43.4 0.0 8.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrB_inter PF17757.1 PXF45670.1 - 1.1e-10 41.5 0.0 4.8e-10 39.5 0.0 2.1 3 0 0 3 3 3 1 UvrB interaction domain ResIII PF04851.15 PXF45670.1 - 4.8e-08 33.2 0.0 7.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 PXF45670.1 - 2.4e-06 27.1 1.0 4.2e-06 26.3 0.2 1.8 2 0 0 2 2 2 1 UvrB/uvrC motif DEAD PF00270.29 PXF45670.1 - 0.0012 18.6 0.4 0.014 15.2 0.0 2.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_30 PF13604.6 PXF45670.1 - 0.0036 17.0 0.6 0.018 14.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain Mito_fiss_reg PF05308.11 PXF45670.1 - 1.1 9.3 6.7 24 4.9 5.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Haemocyan_bet_s PF14830.6 PXF45671.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich HORMA PF02301.18 PXF45672.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 HORMA domain Pkinase PF00069.25 PXF45675.1 - 8.1e-78 261.4 0.0 1e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45675.1 - 7.8e-40 136.8 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45675.1 - 1.6e-09 37.5 0.0 4.5e-08 32.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 PXF45675.1 - 0.00058 19.9 0.0 0.0029 17.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF45675.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF45675.1 - 0.0055 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PXF45675.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PXF45675.1 - 0.015 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 PXF45675.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Hint PF01079.20 PXF45676.1 - 8.2e-19 68.0 0.1 2.4e-18 66.5 0.1 1.6 1 1 0 1 1 1 1 Hint module Ribosomal_TL5_C PF14693.6 PXF45677.1 - 2.3e-10 40.7 0.0 3.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 PXF45677.1 - 0.0082 16.6 0.2 0.1 13.2 0.2 2.3 1 1 0 1 1 1 1 Ribosomal L25p family Ribosomal_L22 PF00237.19 PXF45678.1 - 2.7e-36 123.9 0.0 3.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e tRNA_int_end_N2 PF12928.7 PXF45679.1 - 2.9e-17 62.6 0.0 6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term UQ_con PF00179.26 PXF45680.1 - 1.9e-53 179.8 0.0 2.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PXF45680.1 - 0.004 17.4 0.1 0.0053 17.0 0.1 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 PXF45680.1 - 0.0072 16.0 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RimM PF01782.18 PXF45681.1 - 2.5e-14 53.3 0.0 4.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain Proteasome PF00227.26 PXF45682.1 - 1.4e-48 164.9 0.3 1.7e-48 164.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M20 PF01546.28 PXF45683.1 - 2.3e-25 89.5 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF45683.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Ion_trans_2 PF07885.16 PXF45684.1 - 6.3e-18 64.5 4.2 6.3e-18 64.5 4.2 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 PXF45684.1 - 8.8e-05 21.8 23.1 0.00016 21.0 23.1 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 PXF45684.1 - 0.00045 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain BK_channel_a PF03493.18 PXF45684.1 - 0.00086 19.5 0.0 0.0026 17.9 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit DUF3487 PF11990.8 PXF45684.1 - 0.029 14.2 0.5 0.86 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Lig_chan PF00060.26 PXF45684.1 - 0.055 13.3 0.3 0.055 13.3 0.3 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel Enolase_C PF00113.22 PXF45686.1 - 1.7e-120 401.8 0.1 2.4e-120 401.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PXF45686.1 - 2.3e-49 166.9 0.0 6.8e-49 165.4 0.0 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PXF45686.1 - 8.7e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PXF45686.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MFS_2 PF13347.6 PXF45688.1 - 3e-06 26.1 7.1 3e-06 26.1 7.1 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein Nucleotid_trans PF03407.16 PXF45690.1 - 1.3e-16 61.3 0.0 2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mlo PF03094.15 PXF45691.1 - 5.9e-05 21.6 31.1 8.7e-05 21.1 1.5 3.4 3 0 0 3 3 3 3 Mlo family Serpentine_r_xa PF03383.15 PXF45691.1 - 0.015 15.3 0.0 0.015 15.3 0.0 2.8 3 1 1 4 4 4 0 Caenorhabditis serpentine receptor-like protein, class xa ECSCR PF15820.5 PXF45691.1 - 1.1 9.1 3.9 0.63 9.9 0.5 2.4 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Peptidase_S49_N PF08496.10 PXF45691.1 - 8.9 6.4 6.3 0.46 10.5 0.3 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L15e PF00827.17 PXF45692.1 - 3.8e-89 297.5 10.4 4.4e-89 297.3 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 RRM_1 PF00076.22 PXF45693.1 - 2.8e-14 52.7 0.1 2.1e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PXF45693.1 - 1.8e-05 25.4 0.0 5.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 PXF45693.1 - 0.0018 18.2 2.7 0.0018 18.2 2.7 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PXF45693.1 - 0.002 18.3 0.1 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 PXF45693.1 - 0.003 17.5 3.4 0.003 17.5 3.4 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_2 PF14608.6 PXF45693.1 - 0.066 13.7 1.8 0.18 12.3 1.8 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger OB_RNB PF08206.11 PXF45693.1 - 0.074 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-CCCH_4 PF18044.1 PXF45693.1 - 0.25 11.2 2.9 0.49 10.3 2.9 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Myb_DNA-binding PF00249.31 PXF45695.1 - 5.4e-09 36.1 0.2 8.5e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF45695.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PXF45695.1 - 0.061 13.4 0.1 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glyco_hydro_6 PF01341.17 PXF45697.1 - 1.1e-47 163.3 0.0 1.4e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 HTH_23 PF13384.6 PXF45697.1 - 0.11 12.3 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain PDDEXK_1 PF12705.7 PXF45699.1 - 3.4e-08 33.7 0.0 6.2e-08 32.9 0.0 1.4 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily WD40 PF00400.32 PXF45700.1 - 6.9e-05 23.5 5.5 0.14 13.1 0.2 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Macoilin PF09726.9 PXF45700.1 - 1.2 7.6 4.1 1.7 7.1 4.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4588 PF15251.6 PXF45700.1 - 2.6 7.8 14.0 6.2 6.5 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) ORC4_C PF14629.6 PXF45701.1 - 5.2e-12 45.6 1.4 7e-12 45.2 0.2 1.8 1 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 PXF45701.1 - 0.00015 22.2 4.7 0.0014 19.1 4.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PXF45701.1 - 0.00019 21.4 0.3 0.00041 20.3 0.3 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 PXF45701.1 - 0.0015 19.0 0.0 0.0051 17.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF45701.1 - 0.01 16.1 0.7 0.032 14.5 0.1 2.2 2 1 1 3 3 3 0 AAA domain KAP_NTPase PF07693.14 PXF45701.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 PXF45701.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 PXF45701.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PXF45701.1 - 0.17 11.2 0.0 0.48 9.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 PXF45701.1 - 0.19 11.2 0.0 5.2 6.6 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region EMG1 PF03587.14 PXF45702.1 - 2.6e-69 232.8 0.0 3.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Methyltransf_11 PF08241.12 PXF45703.1 - 5.9e-17 62.1 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF45703.1 - 4.7e-13 49.6 0.0 8.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF45703.1 - 8.2e-12 45.3 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45703.1 - 3.4e-09 37.3 0.0 6.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF45703.1 - 8.7e-08 32.1 0.0 7e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF45703.1 - 6.1e-07 29.0 0.0 8.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 PXF45703.1 - 0.0044 16.9 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 PXF45703.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 PXF45704.1 - 7e-59 199.3 0.0 2.6e-58 197.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45704.1 - 9.9e-28 97.1 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PXF45704.1 - 1e-11 43.5 4.2 0.00064 19.1 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PXF45704.1 - 7.6e-10 37.9 5.1 0.00079 19.2 0.3 4.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PXF45704.1 - 3.3e-09 37.1 5.5 0.0022 18.4 0.0 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 PXF45704.1 - 1e-07 31.7 4.1 1 9.3 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PXF45704.1 - 8.6e-05 21.9 0.9 0.034 13.6 0.1 3.9 4 0 0 4 4 4 1 EF hand APH PF01636.23 PXF45704.1 - 0.0005 20.1 0.6 0.0032 17.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PXF45704.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 PXF45704.1 - 0.018 14.3 0.0 0.06 12.6 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 PXF45704.1 - 0.037 13.6 0.5 0.095 12.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Malectin PF11721.8 PXF45705.1 - 8.9e-22 77.9 0.0 2.9e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 Malectin domain TIG PF01833.24 PXF45705.1 - 6.1e-13 48.7 8.8 2.3e-07 30.8 3.6 3.0 2 0 0 2 2 2 2 IPT/TIG domain GSDH PF07995.11 PXF45705.1 - 3.4e-06 26.6 0.2 7.3e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Malectin_like PF12819.7 PXF45705.1 - 0.00015 21.1 0.1 0.00063 19.0 0.0 1.8 2 0 0 2 2 2 1 Malectin-like domain PKD PF00801.20 PXF45705.1 - 0.031 14.1 0.6 0.35 10.7 0.3 2.7 2 0 0 2 2 2 0 PKD domain bZIP_2 PF07716.15 PXF45706.1 - 7.2e-08 32.4 14.1 1.4e-07 31.5 14.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF45706.1 - 0.0015 18.5 15.8 0.0066 16.5 15.8 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF1515 PF07439.11 PXF45706.1 - 0.013 15.6 1.8 0.019 15.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) bZIP_Maf PF03131.17 PXF45706.1 - 0.018 15.6 6.0 0.018 15.6 6.0 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Tmemb_cc2 PF10267.9 PXF45706.1 - 0.033 13.3 9.4 0.041 13.0 9.4 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Phlebovirus_NSM PF07246.11 PXF45706.1 - 0.75 9.1 5.1 1.1 8.6 5.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cut12 PF11500.8 PXF45706.1 - 2.3 8.2 12.5 0.033 14.1 3.1 2.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein FAM199X PF15814.5 PXF45706.1 - 8.6 5.3 16.0 12 4.9 16.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF760 PF05542.11 PXF45708.1 - 1.9e-28 98.6 0.0 3.1e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) SPX PF03105.19 PXF45708.1 - 1.7 8.5 9.6 2.5 7.9 9.6 1.3 1 0 0 1 1 1 0 SPX domain DUF3481 PF11980.8 PXF45709.1 - 0.72 9.6 3.9 0.36 10.6 0.7 2.0 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Retrotran_gag_2 PF14223.6 PXF45712.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AhpC-TSA PF00578.21 PXF45713.1 - 5e-28 97.5 0.0 6.6e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF45713.1 - 6e-12 45.5 0.0 8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PXF45713.1 - 0.0091 15.8 0.2 0.029 14.2 0.2 1.9 1 1 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 PXF45713.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1989 PF09347.10 PXF45714.1 - 7.3e-55 185.1 0.1 9.1e-55 184.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) ArsA_ATPase PF02374.15 PXF45716.1 - 2.1e-126 421.2 0.0 3.1e-66 223.6 0.0 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 PXF45716.1 - 1.6e-18 67.0 0.0 9e-08 32.2 0.0 2.6 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PXF45716.1 - 8.1e-16 58.4 0.0 1.5e-06 28.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain ParA PF10609.9 PXF45716.1 - 4e-09 36.3 11.3 0.0012 18.4 0.5 4.5 5 0 0 5 5 5 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 PXF45716.1 - 2.5e-06 27.2 0.0 0.081 12.4 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.16 PXF45716.1 - 2.9e-06 26.9 0.4 0.088 12.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein SRP54 PF00448.22 PXF45716.1 - 1.6e-05 24.6 3.6 0.076 12.6 0.1 3.8 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 PXF45716.1 - 1.8e-05 24.4 1.9 0.0046 16.5 0.1 2.4 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ IstB_IS21 PF01695.17 PXF45716.1 - 3.7e-05 23.5 0.2 0.041 13.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein NB-ARC PF00931.22 PXF45716.1 - 3.7e-05 23.0 0.6 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain MeaB PF03308.16 PXF45716.1 - 6.5e-05 22.0 7.7 0.053 12.5 0.0 3.8 5 0 0 5 5 5 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 PXF45716.1 - 0.00019 21.9 8.5 0.034 14.5 0.5 3.5 2 2 1 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.12 PXF45716.1 - 0.00086 18.6 0.4 0.2 10.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 PXF45716.1 - 0.0013 19.0 1.3 1.5 9.1 0.0 3.9 4 1 0 4 4 4 1 AAA domain AAA_30 PF13604.6 PXF45716.1 - 0.0017 18.1 1.3 0.47 10.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF45716.1 - 0.003 18.1 0.8 1.6 9.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF45716.1 - 0.0037 17.0 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PXF45716.1 - 0.004 16.7 3.7 0.47 10.0 0.2 3.2 3 0 0 3 3 3 1 AAA domain PIF1 PF05970.14 PXF45716.1 - 0.01 15.0 0.1 4 6.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DnaB_C PF03796.15 PXF45716.1 - 0.011 15.1 0.3 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Tir_receptor_N PF07490.11 PXF45716.1 - 0.012 15.5 1.2 3.5 7.4 0.1 2.7 3 0 0 3 3 2 0 Translocated intimin receptor (Tir) N-terminus T2SSE PF00437.20 PXF45716.1 - 0.065 12.3 0.1 0.35 9.9 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein APS_kinase PF01583.20 PXF45716.1 - 0.097 12.6 3.9 4.4 7.2 0.1 3.3 4 0 0 4 4 4 0 Adenylylsulphate kinase LpxK PF02606.14 PXF45716.1 - 0.1 11.6 3.5 5.8 5.9 0.1 3.0 3 0 0 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase DUF1611 PF07755.11 PXF45716.1 - 0.11 11.8 0.2 6.2 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain NACHT PF05729.12 PXF45716.1 - 0.14 12.0 4.1 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 PXF45716.1 - 0.18 11.6 3.5 5.4 6.7 0.3 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SMC_N PF02463.19 PXF45716.1 - 0.55 9.6 2.8 13 5.1 0.1 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain CHASE3 PF05227.13 PXF45716.1 - 0.57 10.1 3.6 1.3 9.0 0.5 2.8 2 1 0 2 2 2 0 CHASE3 domain NTPase_1 PF03266.15 PXF45716.1 - 4.1 7.3 6.4 19 5.1 0.4 3.2 3 0 0 3 3 3 0 NTPase AAA PF00004.29 PXF45716.1 - 4.7 7.6 7.2 3 8.3 0.2 3.2 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L18p PF00861.22 PXF45717.1 - 3.6e-14 53.1 0.0 5.9e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast F-box PF00646.33 PXF45718.1 - 0.026 14.4 0.0 0.09 12.7 0.0 2.0 1 0 0 1 1 1 0 F-box domain zf-MYND PF01753.18 PXF45719.1 - 8.7e-10 38.5 12.2 1.5e-09 37.8 12.2 1.4 1 0 0 1 1 1 1 MYND finger Nudix_N_2 PF14803.6 PXF45719.1 - 0.13 12.2 5.5 0.33 10.9 5.5 1.7 1 0 0 1 1 1 0 Nudix N-terminal DZR PF12773.7 PXF45719.1 - 0.25 11.4 3.0 0.55 10.3 3.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 PXF45720.1 - 1.1e-18 67.2 15.0 0.016 16.0 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF45720.1 - 5e-10 39.5 0.0 0.022 15.0 0.0 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF285 PF03382.14 PXF45720.1 - 0.092 12.5 0.5 0.77 9.5 0.1 2.1 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Snf7 PF03357.21 PXF45722.1 - 3.4e-06 26.7 17.3 8e-06 25.6 15.6 1.9 1 1 1 2 2 2 1 Snf7 Tn7_Tnp_TnsA_C PF08721.11 PXF45722.1 - 0.12 13.0 2.0 9.8 6.9 0.1 2.5 1 1 1 2 2 2 0 TnsA endonuclease C terminal Matrilin_ccoil PF10393.9 PXF45722.1 - 1 9.3 3.8 1.6 8.6 0.2 2.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin CemA PF03040.14 PXF45722.1 - 3.4 7.5 7.4 2.2 8.2 4.7 1.7 1 1 1 2 2 2 0 CemA family G6PD_C PF02781.16 PXF45724.1 - 3.5e-104 348.1 0.0 4.5e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PXF45724.1 - 5.5e-51 173.7 0.0 8.2e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ada3 PF10198.9 PXF45725.1 - 0.09 12.9 0.6 0.19 11.8 0.6 1.6 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 ECH_2 PF16113.5 PXF45725.1 - 0.98 8.8 3.6 12 5.2 0.2 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase APAF1_C PF17908.1 PXF45726.1 - 0.00034 20.6 0.2 0.00068 19.7 0.2 1.5 1 0 0 1 1 1 1 APAF-1 helical domain ANAPC4_WD40 PF12894.7 PXF45727.1 - 6.8e-14 51.9 2.8 3e-07 30.6 0.1 4.2 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF45727.1 - 2.2e-07 31.4 11.5 0.0026 18.5 1.6 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 PXF45727.1 - 7.5e-07 29.2 2.4 0.00034 20.6 0.2 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PXF45727.1 - 1.1e-05 25.2 0.2 2.1 8.4 0.0 5.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 PXF45727.1 - 0.00053 18.6 0.1 0.025 13.1 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PXF45727.1 - 0.035 13.1 0.0 0.59 9.0 0.0 2.5 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 PXF45727.1 - 0.13 11.0 0.3 1 8.0 0.2 2.2 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cyt_bd_oxida_II PF02322.15 PXF45728.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II CTP_transf_1 PF01148.20 PXF45729.1 - 1e-64 218.9 18.8 1.4e-64 218.5 18.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family FixS PF03597.15 PXF45729.1 - 0.25 11.1 4.1 0.55 10.0 0.1 2.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type adh_short PF00106.25 PXF45731.1 - 7.6e-39 133.2 0.0 9.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF45731.1 - 2e-19 70.1 0.0 2.6e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF45731.1 - 5.9e-10 39.3 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF45731.1 - 0.0022 17.9 0.1 0.003 17.5 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PXF45731.1 - 0.004 16.6 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PXF45731.1 - 0.013 14.7 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PXF45731.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Leo1 PF04004.13 PXF45732.1 - 2.7e-09 37.1 0.3 8.9e-09 35.4 0.0 2.0 1 1 1 2 2 2 1 Leo1-like protein ArsA_ATPase PF02374.15 PXF45733.1 - 6.8e-191 633.0 1.4 2.8e-95 319.0 0.4 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 PXF45733.1 - 2.6e-28 99.2 0.0 9.1e-14 51.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain CbiA PF01656.23 PXF45733.1 - 9.5e-26 90.3 2.5 3.1e-11 43.5 0.0 3.9 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 PXF45733.1 - 5.5e-14 52.3 0.3 6.4e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 PXF45733.1 - 8.5e-12 45.1 2.7 0.00047 19.8 0.1 4.2 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 PXF45733.1 - 1.2e-11 44.6 0.1 0.00012 21.6 0.0 3.1 4 0 0 4 4 3 2 Cellulose biosynthesis protein BcsQ ParA PF10609.9 PXF45733.1 - 5.2e-09 35.9 12.8 7.5e-05 22.3 0.5 3.5 4 0 0 4 4 3 2 NUBPL iron-transfer P-loop NTPase Zeta_toxin PF06414.12 PXF45733.1 - 1.1e-06 28.1 0.1 0.05 12.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MeaB PF03308.16 PXF45733.1 - 3.8e-06 26.1 0.2 0.00099 18.2 0.1 2.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 PXF45733.1 - 4.8e-06 26.0 0.2 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 VirC1 protein AAA_16 PF13191.6 PXF45733.1 - 1.7e-05 25.3 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 PXF45733.1 - 2.7e-05 23.5 3.6 0.048 12.9 0.1 2.8 3 0 0 3 3 3 2 NB-ARC domain MipZ PF09140.11 PXF45733.1 - 5.3e-05 22.6 3.3 0.16 11.3 0.0 3.5 3 1 0 4 4 4 2 ATPase MipZ PhoH PF02562.16 PXF45733.1 - 6e-05 22.6 0.3 0.32 10.4 0.0 3.6 3 0 0 3 3 3 1 PhoH-like protein ATP_bind_1 PF03029.17 PXF45733.1 - 7.1e-05 22.7 9.1 0.29 10.9 0.3 4.0 4 0 0 4 4 3 2 Conserved hypothetical ATP binding protein T2SSE PF00437.20 PXF45733.1 - 9.9e-05 21.5 0.2 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.6 PXF45733.1 - 0.00012 22.6 1.9 0.58 10.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PXF45733.1 - 0.0002 21.1 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 PXF45733.1 - 0.00028 20.7 1.4 0.048 13.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF1611 PF07755.11 PXF45733.1 - 0.0005 19.4 0.1 0.33 10.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain AAA_30 PF13604.6 PXF45733.1 - 0.00061 19.6 0.2 0.57 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 PXF45733.1 - 0.00089 18.5 0.2 0.99 8.5 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase CTP_synth_N PF06418.14 PXF45733.1 - 0.0019 17.6 0.4 0.62 9.3 0.1 3.1 2 0 0 2 2 2 1 CTP synthase N-terminus Lebercilin PF15619.6 PXF45733.1 - 0.0021 17.8 1.3 0.0038 16.9 1.3 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease RNA_helicase PF00910.22 PXF45733.1 - 0.0032 17.8 0.2 2.5 8.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase KTI12 PF08433.10 PXF45733.1 - 0.0038 16.7 0.1 3.4 7.1 0.0 2.5 2 0 0 2 2 2 2 Chromatin associated protein KTI12 ResIII PF04851.15 PXF45733.1 - 0.0045 17.0 0.2 2.2 8.3 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 PXF45733.1 - 0.0053 16.1 0.1 0.21 10.9 0.0 2.8 3 0 0 3 3 2 1 KaiC AAA_25 PF13481.6 PXF45733.1 - 0.0088 15.6 7.1 0.3 10.6 0.3 3.8 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PXF45733.1 - 0.0096 16.1 0.1 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PXF45733.1 - 0.012 15.5 4.9 1.7 8.5 0.1 3.3 4 0 0 4 4 3 0 Adenylylsulphate kinase BALF1 PF06861.11 PXF45733.1 - 0.014 15.1 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 BALF1 protein ABC_tran PF00005.27 PXF45733.1 - 0.018 15.5 0.3 6.1 7.4 0.0 2.7 3 0 0 3 3 2 0 ABC transporter HTH_ParB PF17762.1 PXF45733.1 - 0.02 14.7 0.1 2.4 8.0 0.0 2.9 2 0 0 2 2 2 0 HTH domain found in ParB protein STAT_int PF02865.17 PXF45733.1 - 0.03 14.8 0.4 5.2 7.5 0.0 3.0 2 0 0 2 2 2 0 STAT protein, protein interaction domain Mur_ligase_M PF08245.12 PXF45733.1 - 0.042 13.8 0.3 7 6.6 0.1 2.6 2 0 0 2 2 2 0 Mur ligase middle domain Erp_C PF06780.11 PXF45733.1 - 0.11 12.5 0.8 0.23 11.5 0.1 1.9 2 0 0 2 2 1 0 Erp protein C-terminus FTHFS PF01268.19 PXF45733.1 - 0.13 10.4 4.3 4.6 5.3 0.1 3.2 3 0 0 3 3 3 0 Formate--tetrahydrofolate ligase CLP1_P PF16575.5 PXF45733.1 - 0.14 12.0 1.5 17 5.1 0.1 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 PXF45733.1 - 0.18 11.7 7.7 2.6 7.9 0.2 3.5 3 1 0 3 3 3 0 NTPase RPW8 PF05659.11 PXF45733.1 - 0.18 11.5 5.3 0.21 11.3 3.1 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DASH_Dad2 PF08654.10 PXF45733.1 - 0.2 12.1 2.1 0.6 10.6 0.1 2.6 3 0 0 3 3 2 0 DASH complex subunit Dad2 NACHT PF05729.12 PXF45733.1 - 0.56 10.1 4.4 2 8.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain TMPIT PF07851.13 PXF45733.1 - 1.6 7.9 3.6 1.7 7.8 0.3 2.3 2 1 1 3 3 3 0 TMPIT-like protein FMN_red PF03358.15 PXF45734.1 - 4.3e-19 68.8 0.0 6.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase HEAT PF02985.22 PXF45735.1 - 2.5e-14 52.2 6.8 0.015 15.5 0.1 7.5 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 PXF45735.1 - 3.1e-09 37.1 3.8 5.2e-07 30.0 0.5 4.7 4 1 1 5 5 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PXF45735.1 - 5.6e-08 33.3 0.0 1.6e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 PXF45735.1 - 5.9e-07 29.8 0.7 9.1e-05 22.8 0.1 3.6 3 2 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 PXF45735.1 - 0.00022 21.3 0.0 0.0038 17.3 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 PXF45735.1 - 0.02 15.2 0.1 15 6.0 0.0 3.0 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Cohesin_HEAT PF12765.7 PXF45735.1 - 0.021 15.1 0.0 19 5.7 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Phosphorylase PF00343.20 PXF45736.1 - 0 1017.5 0.0 0 1017.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase ABC_membrane PF00664.23 PXF45737.1 - 1.6e-119 398.6 23.6 5.6e-65 219.7 10.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF45737.1 - 4.2e-71 237.8 0.1 4.6e-35 121.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PXF45737.1 - 3.3e-12 46.3 2.1 0.00029 20.3 0.8 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PXF45737.1 - 2.4e-08 34.6 3.1 0.00025 21.5 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PXF45737.1 - 2.6e-08 34.2 1.7 0.0045 17.3 0.1 4.3 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 PXF45737.1 - 2.3e-07 30.0 0.8 0.022 13.6 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 PXF45737.1 - 2.6e-07 30.1 0.1 0.013 14.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 PXF45737.1 - 1.9e-06 27.9 0.0 0.03 14.2 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 PXF45737.1 - 2.2e-06 28.1 0.4 1.2 9.6 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PXF45737.1 - 6.1e-06 26.1 1.2 0.18 11.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PXF45737.1 - 8.6e-06 25.4 0.2 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 PXF45737.1 - 1.5e-05 25.1 0.0 0.18 11.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 PXF45737.1 - 0.0002 21.2 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 PXF45737.1 - 0.0004 20.4 0.0 1.1 9.2 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain DUF87 PF01935.17 PXF45737.1 - 0.00048 20.3 0.4 1.3 9.0 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain G-alpha PF00503.20 PXF45737.1 - 0.00072 18.8 0.0 0.85 8.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 PXF45737.1 - 0.002 18.3 3.5 0.63 10.3 0.6 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 PXF45737.1 - 0.0021 17.9 0.0 2.7 7.7 0.0 3.2 3 1 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 PXF45737.1 - 0.0023 18.2 0.2 1.3 9.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 PXF45737.1 - 0.0023 17.1 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 PXF45737.1 - 0.0025 17.4 0.5 2.8 7.5 0.1 3.1 3 0 0 3 3 2 1 AAA domain DUF2207 PF09972.9 PXF45737.1 - 0.0026 16.6 7.8 0.011 14.5 0.0 3.4 3 0 0 3 3 3 1 Predicted membrane protein (DUF2207) PRK PF00485.18 PXF45737.1 - 0.003 17.3 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 PXF45737.1 - 0.0057 16.4 0.0 4.8 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PXF45737.1 - 0.014 15.8 0.0 7 7.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 PXF45737.1 - 0.021 15.0 0.0 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PXF45737.1 - 0.031 14.8 0.1 11 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 PXF45737.1 - 0.031 14.2 0.4 7 6.5 0.0 3.0 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 PXF45737.1 - 0.036 14.1 0.0 1.4 9.0 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 PXF45737.1 - 0.036 13.6 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 PXF45737.1 - 0.04 13.1 0.0 0.92 8.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rop-like PF05082.13 PXF45737.1 - 0.042 13.7 0.4 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Rop-like ATP-synt_ab PF00006.25 PXF45737.1 - 0.047 13.3 0.1 2.4 7.8 0.0 2.8 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 PXF45737.1 - 0.054 14.0 0.0 7.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PXF45737.1 - 0.059 13.3 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 PXF45737.1 - 0.064 13.2 0.0 2.7 7.9 0.0 2.7 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 PXF45737.1 - 0.073 13.2 0.0 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dala_Dala_lig_N PF01820.21 PXF45737.1 - 0.12 12.8 0.0 5.4 7.5 0.0 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DEP PF00610.21 PXF45739.1 - 7.1e-25 86.9 0.1 1.7e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MGS PF02142.22 PXF45739.1 - 8.9e-17 61.1 0.0 2e-16 59.9 0.0 1.6 2 0 0 2 2 2 1 MGS-like domain Cnn_1N PF07989.11 PXF45740.1 - 0.00019 21.5 7.9 0.00019 21.5 7.9 5.2 1 1 3 4 4 4 1 Centrosomin N-terminal motif 1 CENP-H PF05837.12 PXF45740.1 - 0.00066 20.1 10.5 0.00066 20.1 10.5 4.3 1 1 2 3 3 3 1 Centromere protein H (CENP-H) RNaseH_C PF09293.10 PXF45740.1 - 0.043 14.1 2.9 0.29 11.5 0.1 2.8 2 1 0 2 2 2 0 T4 RNase H, C terminal DUF4089 PF13318.6 PXF45740.1 - 0.062 13.8 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Taxilin PF09728.9 PXF45740.1 - 0.069 12.3 48.9 0.018 14.2 17.3 3.4 2 1 1 3 3 3 0 Myosin-like coiled-coil protein HSP20 PF00011.21 PXF45741.1 - 4.1e-07 30.1 0.0 0.0046 17.1 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF45741.1 - 0.00016 21.1 0.0 0.00089 18.8 0.0 2.0 2 0 0 2 2 2 1 HSP20-like domain found in ArsA DUF202 PF02656.15 PXF45742.1 - 8.9e-07 29.3 1.4 8.9e-07 29.3 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SAM_1 PF00536.30 PXF45742.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PXF45742.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) APO_RNA-bind PF05634.11 PXF45742.1 - 0.049 13.0 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 APO RNA-binding FlgN PF05130.12 PXF45743.1 - 0.11 13.0 1.2 0.18 12.3 1.2 1.3 1 0 0 1 1 1 0 FlgN protein NAD_binding_10 PF13460.6 PXF45744.1 - 2e-21 76.7 0.0 2.3e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 PXF45744.1 - 5.9e-08 32.9 0.0 9.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 PXF45744.1 - 3.4e-06 26.8 0.1 3.5e-05 23.5 0.2 2.1 2 1 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.24 PXF45744.1 - 3.6e-06 27.4 0.0 6.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 PXF45744.1 - 7.6e-05 22.3 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 PXF45744.1 - 0.0027 18.4 0.0 0.0039 17.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 PXF45744.1 - 0.04 14.7 0.1 0.059 14.2 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.6 PXF45745.1 - 1.2e-19 70.9 0.0 1.5e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 PXF45745.1 - 2.6e-06 27.6 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 PXF45745.1 - 0.00025 21.5 0.0 0.0004 20.8 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 PXF45745.1 - 0.0014 18.2 0.2 0.0022 17.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF45745.1 - 0.026 14.0 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 PXF45745.1 - 0.043 14.5 0.1 0.068 13.9 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 PXF45745.1 - 0.13 13.1 0.1 0.2 12.5 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_10 PF13460.6 PXF45746.1 - 2.8e-15 56.7 0.0 3.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding PfkB PF00294.24 PXF45746.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Hint PF01079.20 PXF45747.1 - 3e-20 72.6 0.0 6.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Hint module Pentapeptide_3 PF13576.6 PXF45747.1 - 1.1e-11 44.7 42.3 4.8e-06 26.6 8.7 6.6 6 1 1 7 7 7 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 PXF45747.1 - 3.9e-09 36.6 28.6 0.0022 18.1 7.4 5.4 2 2 3 5 5 5 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 PXF45747.1 - 0.021 14.5 12.1 6.4 6.5 0.3 5.5 3 2 0 3 3 3 0 Pentapeptide repeats (8 copies) CMD PF02627.20 PXF45748.1 - 2.5e-09 37.0 4.3 7.8e-09 35.5 1.1 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BTRD1 PF17660.1 PXF45748.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Sec23_trunk PF04811.15 PXF45749.1 - 4.6e-52 177.0 0.0 6.3e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PXF45749.1 - 7.8e-17 61.8 0.0 1.4e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 PXF45749.1 - 5.7e-16 58.3 5.0 1.5e-15 57.0 5.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 PXF45749.1 - 9.3e-13 47.9 0.6 1.8e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Vps36-NZF-N PF16988.5 PXF45749.1 - 0.0026 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cyt-b5 PF00173.28 PXF45750.1 - 7.9e-07 29.1 0.3 2.8e-06 27.4 0.3 2.0 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SURF4 PF02077.15 PXF45751.1 - 1.2e-48 166.1 9.4 1.5e-48 165.7 9.4 1.0 1 0 0 1 1 1 1 SURF4 family Kelch_4 PF13418.6 PXF45752.1 - 7.1e-20 70.8 9.6 1.1e-06 28.5 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF45752.1 - 2.3e-15 56.5 5.5 6.4e-05 23.1 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PXF45752.1 - 6.7e-10 38.7 0.6 0.13 12.2 0.0 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 PXF45752.1 - 4.3e-09 36.3 4.9 0.2 12.0 0.0 5.8 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 PXF45752.1 - 1.3e-05 24.7 10.3 0.22 11.1 0.1 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 PXF45752.1 - 0.023 14.7 14.6 1.4 9.0 0.0 5.7 6 1 0 6 6 6 0 Kelch motif Tetraspanin PF00335.20 PXF45753.1 - 0.00011 22.0 9.0 0.00019 21.2 9.0 1.3 1 0 0 1 1 1 1 Tetraspanin family DnaJ PF00226.31 PXF45756.1 - 1.8e-16 60.0 0.3 4e-16 58.9 0.0 1.8 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.17 PXF45756.1 - 6.9e-12 44.5 2.4 0.0038 17.2 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PXF45756.1 - 9.1e-09 34.8 2.4 0.0036 17.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45756.1 - 5.2e-06 26.8 0.8 0.079 13.8 0.1 3.7 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45756.1 - 3.1e-05 23.5 3.1 0.0001 21.9 3.1 2.0 1 0 0 1 1 1 1 TPR repeat Fis1_TPR_C PF14853.6 PXF45756.1 - 0.00013 21.9 0.9 0.032 14.3 0.0 3.6 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 PXF45756.1 - 0.00018 21.7 1.8 0.06 13.7 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF45756.1 - 0.00023 21.8 1.3 0.029 15.0 1.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF45756.1 - 0.00066 20.1 4.9 0.003 18.0 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF45756.1 - 0.00067 19.8 0.0 0.18 11.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45756.1 - 0.0046 17.1 1.4 6.9 7.2 0.5 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2207 PF09972.9 PXF45756.1 - 0.041 12.6 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.23 PXF45756.1 - 0.11 12.1 2.2 0.16 11.6 2.2 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region MIT PF04212.18 PXF45756.1 - 0.15 12.2 3.3 0.55 10.3 0.4 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Tmemb_9 PF05434.11 PXF45756.1 - 6.5 6.6 6.1 0.55 10.1 1.1 1.8 2 0 0 2 2 2 0 TMEM9 SARAF PF06682.12 PXF45758.1 - 7.2e-32 111.3 0.1 1e-31 110.9 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis KOW PF00467.29 PXF45759.1 - 3.8e-23 80.6 25.2 4.7e-05 23.2 0.0 6.9 6 0 0 6 6 6 6 KOW motif Spt5-NGN PF03439.13 PXF45759.1 - 1.4e-15 56.9 0.1 4.6e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 PXF45759.1 - 3.9e-08 34.2 12.9 3.9e-08 34.2 12.9 3.2 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF150_C PF17384.2 PXF45759.1 - 0.00015 21.8 16.3 1.1 9.4 0.1 5.7 5 1 1 6 6 6 3 RimP C-terminal SH3 domain YajC PF02699.15 PXF45759.1 - 0.2 11.6 3.6 7.2 6.6 0.1 3.7 2 1 1 3 3 3 0 Preprotein translocase subunit RRM_1 PF00076.22 PXF45760.1 - 0.0021 17.8 0.0 0.0049 16.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Polyketide_cyc2 PF10604.9 PXF45761.1 - 1.6e-08 34.9 0.0 2.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PXF45761.1 - 5.5e-08 33.1 0.2 7.3e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CHD5 PF04420.14 PXF45762.1 - 0.02 14.8 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 CHD5-like protein Upf2 PF04050.14 PXF45762.1 - 0.13 13.0 3.9 0.24 12.1 3.3 1.6 1 1 1 2 2 2 0 Up-frameshift suppressor 2 AAA PF00004.29 PXF45763.1 - 7.6e-16 58.7 0.0 4.3e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PXF45763.1 - 2.8e-10 40.2 0.0 3e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 PXF45763.1 - 4.6e-08 33.4 0.0 9.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_16 PF13191.6 PXF45763.1 - 7.5e-07 29.7 0.2 1.8e-05 25.2 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 PXF45763.1 - 9.2e-07 28.7 0.0 2.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 PXF45763.1 - 6.3e-06 26.2 0.0 1.2e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 PXF45763.1 - 9.7e-06 25.8 0.3 3.3e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA_5 PF07728.14 PXF45763.1 - 4.9e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF45763.1 - 6.7e-05 23.2 0.1 0.0022 18.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF45763.1 - 0.00012 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PXF45763.1 - 0.00035 20.4 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PXF45763.1 - 0.0018 17.7 0.0 0.07 12.5 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 PXF45763.1 - 0.0022 18.0 0.0 0.0066 16.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF45763.1 - 0.0061 16.3 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF45763.1 - 0.011 16.0 0.1 0.051 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PXF45763.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 PXF45763.1 - 0.016 14.6 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 PXF45763.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 PXF45763.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 PXF45763.1 - 0.028 14.0 0.0 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 PXF45763.1 - 0.033 14.0 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TIP49 PF06068.13 PXF45763.1 - 0.04 13.1 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 PXF45763.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 PXF45763.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 PXF45764.1 - 1.1e-67 228.2 0.0 1.4e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45764.1 - 4.2e-48 163.9 0.0 6e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF45764.1 - 0.0021 16.9 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF1682 PF07946.14 PXF45765.1 - 5.3e-54 183.6 1.9 7e-54 183.2 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Tmemb_18A PF09771.9 PXF45765.1 - 0.066 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 TPR_2 PF07719.17 PXF45766.1 - 4.9e-13 48.1 8.6 0.0035 17.3 0.0 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45766.1 - 5.6e-11 41.8 4.4 0.088 13.1 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PXF45766.1 - 5.5e-10 39.6 5.0 0.0019 18.6 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45766.1 - 1.3e-07 31.8 12.0 0.014 16.2 0.2 5.6 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF45766.1 - 1.1e-05 25.6 12.3 0.067 13.5 0.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF45766.1 - 1.3e-05 24.8 2.3 0.027 14.3 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45766.1 - 0.00012 21.7 0.3 0.0037 16.9 0.0 3.2 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 PXF45766.1 - 0.00015 22.3 7.4 0.37 11.5 1.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PXF45766.1 - 0.00024 21.3 1.5 5.6 7.6 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PXF45766.1 - 0.00052 20.5 10.5 3.8 8.4 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 PXF45766.1 - 0.0013 17.8 0.4 0.0023 16.9 0.4 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 PXF45766.1 - 0.0014 18.6 10.7 4.2 7.6 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 PXF45766.1 - 0.029 14.7 5.4 1.9 8.9 1.0 3.3 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PXF45766.1 - 0.046 14.3 4.9 36 5.4 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PXF45766.1 - 0.072 13.2 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Flg_hook PF02120.16 PXF45766.1 - 0.075 12.9 0.5 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK TPR_10 PF13374.6 PXF45766.1 - 0.086 12.7 0.4 0.086 12.7 0.4 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Caps_synth_GfcC PF06251.11 PXF45766.1 - 0.51 9.9 2.7 8.4 5.9 0.7 2.3 1 1 1 2 2 2 0 Capsule biosynthesis GfcC Wzy_C_2 PF11846.8 PXF45766.1 - 0.84 9.5 3.9 9 6.2 0.9 2.9 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Pyr_redox_2 PF07992.14 PXF45767.1 - 1e-23 84.1 0.1 2e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF45767.1 - 6.1e-07 29.3 0.7 1.8e-05 24.5 0.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PXF45767.1 - 4.2e-05 24.0 0.0 0.4 11.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 PXF45767.1 - 4.3e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 PXF45767.1 - 0.00076 19.5 0.2 0.87 9.6 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 PXF45767.1 - 0.00099 18.3 0.0 0.0099 15.1 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PXF45767.1 - 0.0013 18.9 0.0 0.0081 16.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 PXF45767.1 - 0.023 13.3 0.1 1.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.6 PXF45767.1 - 0.029 13.6 0.0 6.3 6.0 0.0 3.2 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TraB PF01963.17 PXF45767.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 TraB family HI0933_like PF03486.14 PXF45767.1 - 0.13 10.9 0.0 6.7 5.3 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 PXF45767.1 - 0.16 10.8 0.0 0.43 9.4 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 PXF45767.1 - 1.3 8.1 2.7 2.5 7.1 1.0 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A Kelch_6 PF13964.6 PXF45768.1 - 7.4e-22 76.8 17.8 0.0005 20.3 0.0 6.1 3 1 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PXF45768.1 - 9.6e-16 57.1 24.0 0.00019 20.9 1.9 7.2 6 2 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PXF45768.1 - 5.3e-15 55.3 18.1 0.00015 21.9 0.2 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PXF45768.1 - 6e-14 51.8 22.5 0.0048 16.9 0.0 6.1 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PXF45768.1 - 1.7e-08 34.1 19.6 0.053 13.5 0.5 6.5 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PXF45768.1 - 4.7e-05 23.3 10.8 0.038 14.0 0.2 5.0 5 0 0 5 5 5 2 Kelch motif PQQ_3 PF13570.6 PXF45768.1 - 0.048 14.2 6.4 18 6.0 0.2 3.7 3 0 0 3 3 3 0 PQQ-like domain Kelch_6 PF13964.6 PXF45769.1 - 5.8e-22 77.2 15.1 0.00039 20.6 0.3 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PXF45769.1 - 1.1e-13 51.0 19.8 0.0017 18.4 0.2 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PXF45769.1 - 3.7e-12 45.6 33.7 2e-05 24.0 1.1 7.5 7 2 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 PXF45769.1 - 3.4e-11 42.7 16.2 0.0066 16.4 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PXF45769.1 - 1.9e-07 30.9 16.0 0.017 15.1 0.2 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PXF45769.1 - 3.1e-07 30.5 42.0 0.00044 20.5 0.2 7.2 8 1 0 8 8 8 4 Galactose oxidase, central domain PRCC PF10253.9 PXF45769.1 - 0.66 10.7 9.6 1.2 9.8 9.6 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Nbl1_Borealin_N PF10444.9 PXF45772.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal LST1 PF05083.13 PXF45776.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 1 1 2 2 2 0 LST-1 protein Med15 PF09606.10 PXF45776.1 - 0.15 10.7 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4895 PF16236.5 PXF45776.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4895) Phage_tail_3 PF08813.11 PXF45779.1 - 0.022 14.3 0.1 0.054 13.1 0.1 1.6 1 1 0 1 1 1 0 Phage tail tube protein, TTP Nucleoporin2 PF04096.14 PXF45782.1 - 5.7e-29 101.2 0.0 7.1e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin autopeptidase Pex16 PF08610.10 PXF45784.1 - 0.025 13.8 0.3 0.035 13.3 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) M60-like_N PF17291.2 PXF45785.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases PhrC_PhrF PF11131.8 PXF45786.1 - 0.03 13.9 2.7 0.043 13.4 2.1 1.6 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF4064 PF13273.6 PXF45787.1 - 0.013 15.7 0.2 0.48 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) LHC PF00556.20 PXF45787.1 - 1.8 8.8 5.1 4.7 7.5 5.1 1.7 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Dodecin PF07311.12 PXF45790.1 - 0.098 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Dodecin Lig_chan PF00060.26 PXF45793.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 PXF45793.1 - 1.4e-05 24.6 0.0 7.7e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3176 PF11374.8 PXF45793.1 - 4.1 7.7 5.4 4.4 7.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3176) zf-C2H2_4 PF13894.6 PXF45795.1 - 0.083 13.8 1.5 0.083 13.8 1.5 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger AcetDehyd-dimer PF09290.11 PXF45795.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Integrin_beta PF00362.18 PXF45797.1 - 6.6e-07 29.2 0.0 0.013 15.2 0.0 2.3 1 1 1 2 2 2 2 Integrin beta chain VWA domain VWA_2 PF13519.6 PXF45797.1 - 0.0079 16.8 0.0 0.09 13.4 0.0 2.4 1 1 2 3 3 3 1 von Willebrand factor type A domain CAP PF00188.26 PXF45798.1 - 1.9e-16 61.1 0.0 2.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MLANA PF14991.6 PXF45799.1 - 0.00075 19.8 0.2 0.0011 19.2 0.2 1.2 1 0 0 1 1 1 1 Protein melan-A Stevor PF17410.2 PXF45799.1 - 0.00081 19.0 0.1 0.00081 19.0 0.1 1.3 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame Herpes_gE PF02480.16 PXF45799.1 - 0.0042 15.9 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 PXF45799.1 - 0.0088 16.9 0.2 0.017 16.0 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Phage_holin_3_6 PF07332.11 PXF45799.1 - 0.043 13.8 0.2 0.35 10.9 0.2 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECSCR PF15820.5 PXF45799.1 - 0.044 13.6 0.2 0.059 13.2 0.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LST1 PF05083.13 PXF45799.1 - 0.063 13.6 1.4 0.12 12.7 1.4 1.5 1 0 0 1 1 1 0 LST-1 protein LapA_dom PF06305.11 PXF45799.1 - 0.086 12.7 1.1 0.14 12.0 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amnionless PF14828.6 PXF45799.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless CoatB PF10389.9 PXF45799.1 - 0.18 11.7 4.5 0.39 10.6 4.5 1.5 1 0 0 1 1 1 0 Bacteriophage coat protein B FeoB_associated PF12669.7 PXF45799.1 - 0.24 11.8 2.2 0.42 11.1 1.0 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Pyr_redox_2 PF07992.14 PXF45801.1 - 1.3e-42 146.1 0.0 1.9e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF45801.1 - 4.2e-09 36.8 0.0 1.5e-07 31.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sel1 PF08238.12 PXF45803.1 - 8.3e-19 67.6 12.7 2.2e-05 25.0 0.2 6.4 6 0 0 6 6 6 4 Sel1 repeat Pkinase PF00069.25 PXF45803.1 - 5.5e-10 39.1 0.0 0.00044 19.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45803.1 - 0.0086 15.4 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_2 PF07723.13 PXF45807.1 - 1.4 9.7 4.3 69 4.3 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat MBOAT PF03062.19 PXF45808.1 - 5.8e-28 98.2 19.3 5.8e-28 98.2 19.3 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PXF45808.1 - 6.4e-05 23.2 4.4 0.00029 21.0 4.4 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PP2C PF00481.21 PXF45810.1 - 1.5e-28 100.2 0.0 1.8e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF45810.1 - 1e-08 35.1 0.3 1.8e-08 34.2 0.3 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PXF45810.1 - 0.00033 20.6 0.3 0.0043 17.0 0.2 2.4 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) Anoctamin PF04547.12 PXF45811.1 - 2.8e-97 326.4 0.0 4.2e-97 325.8 0.0 1.3 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PXF45811.1 - 0.0023 17.7 0.0 1.1 8.9 0.0 2.6 1 1 1 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Branch PF02485.21 PXF45812.1 - 1.3e-30 106.7 0.2 2.9e-30 105.6 0.2 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme DUF4537 PF15057.6 PXF45814.1 - 0.18 11.8 1.5 0.55 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 PXF45814.1 - 0.68 9.7 6.0 1.7 8.4 1.7 2.5 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 RasGAP_C PF03836.15 PXF45815.1 - 0.057 13.6 0.2 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 RasGAP C-terminus Tudor_3 PF18115.1 PXF45815.1 - 0.16 11.9 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Phasin_2 PF09361.10 PXF45815.1 - 0.76 10.1 5.6 12 6.3 2.4 2.3 2 0 0 2 2 2 0 Phasin protein ABC_tran PF00005.27 PXF45816.1 - 5.5e-44 150.0 0.0 1.9e-20 73.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PXF45816.1 - 6.8e-22 77.3 3.4 6.8e-22 77.3 3.4 2.3 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 PXF45816.1 - 2.1e-19 70.5 1.8 3.1e-05 23.9 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF45816.1 - 1.2e-09 37.9 0.9 0.52 9.7 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PXF45816.1 - 4.6e-07 29.9 1.7 0.0021 18.0 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 PXF45816.1 - 8.2e-07 28.7 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF45816.1 - 5.8e-06 27.0 8.6 0.043 14.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 PXF45816.1 - 6.2e-06 26.3 0.0 0.034 14.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 PXF45816.1 - 1.1e-05 25.6 2.0 0.049 13.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 PXF45816.1 - 6.9e-05 23.3 0.0 0.054 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 PXF45816.1 - 9.3e-05 22.3 6.1 0.092 12.4 2.1 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 PXF45816.1 - 0.00011 22.6 0.0 0.34 11.3 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF45816.1 - 0.00017 21.9 0.0 0.37 11.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 PXF45816.1 - 0.00028 20.8 0.0 0.85 9.5 0.0 2.7 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 PXF45816.1 - 0.00044 20.3 0.0 1.7 8.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 PXF45816.1 - 0.00049 20.7 0.0 0.64 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PXF45816.1 - 0.00056 20.2 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF45816.1 - 0.00065 20.1 0.4 1.9 8.9 0.0 2.8 3 0 0 3 3 2 2 RNA helicase Rad17 PF03215.15 PXF45816.1 - 0.0016 18.4 0.1 0.4 10.6 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_5 PF07728.14 PXF45816.1 - 0.0052 16.8 0.3 5.9 6.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PXF45816.1 - 0.0066 16.2 0.1 5.2 6.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 PXF45816.1 - 0.017 14.8 0.9 5.2 6.7 0.0 3.8 4 1 0 4 4 3 0 AAA domain dNK PF01712.19 PXF45816.1 - 0.018 14.9 0.0 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 PXF45816.1 - 0.02 14.4 0.1 1.4 8.4 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 PXF45816.1 - 0.024 15.0 0.0 13 6.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PXF45816.1 - 0.037 14.0 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KapB PF08810.10 PXF45816.1 - 0.07 13.3 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinase associated protein B Zeta_toxin PF06414.12 PXF45816.1 - 0.079 12.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 PXF45816.1 - 0.084 12.8 2.0 8.9 6.2 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 PXF45816.1 - 0.086 13.1 0.0 9.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 PXF45816.1 - 0.088 11.8 0.1 20 4.0 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 PXF45816.1 - 0.095 12.6 0.0 5.7 6.8 0.0 2.9 3 0 0 3 3 2 0 NTPase Dynamin_N PF00350.23 PXF45816.1 - 0.096 12.7 7.3 2.1 8.4 0.0 3.9 4 1 1 5 5 5 0 Dynamin family PRK PF00485.18 PXF45816.1 - 0.1 12.3 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_27 PF13514.6 PXF45816.1 - 0.11 12.0 4.5 1.6 8.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 PXF45816.1 - 0.13 11.8 0.0 13 5.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 PXF45816.1 - 0.16 11.5 0.2 1 8.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PXF45816.1 - 0.17 11.6 0.3 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 PXF45816.1 - 0.51 10.4 6.6 2.8 8.0 0.0 3.1 4 1 0 4 4 2 0 Helicase HerA, central domain AAA_13 PF13166.6 PXF45816.1 - 2.9 6.4 6.6 41 2.6 0.0 3.8 2 1 1 3 3 3 0 AAA domain Trypsin PF00089.26 PXF45817.1 - 6.7e-31 107.8 0.0 7.8e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF45817.1 - 5.6e-10 40.3 0.0 9.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DDRGK PF09756.9 PXF45818.1 - 0.058 13.0 16.0 0.094 12.3 16.0 1.3 1 0 0 1 1 1 0 DDRGK domain DUF2058 PF09831.9 PXF45818.1 - 1.1 9.4 9.5 2 8.6 9.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Trypsin PF00089.26 PXF45819.1 - 7.9e-29 101.0 0.1 9.6e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF45819.1 - 3.5e-13 50.7 0.1 5.9e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF45820.1 - 3.5e-25 89.1 0.0 4.4e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF45820.1 - 1.3e-06 29.4 0.0 3.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain FGE-sulfatase PF03781.16 PXF45821.1 - 1.8e-28 99.9 1.7 6.6e-19 68.5 2.4 2.1 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DUF3040 PF11239.8 PXF45822.1 - 0.44 10.9 2.8 5.9 7.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) MCR_gamma PF02240.16 PXF45823.1 - 0.076 12.2 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit U62_UL91 PF17442.2 PXF45825.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins TPT PF03151.16 PXF45827.1 - 1.3e-10 41.1 19.3 1.7e-10 40.7 19.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF45827.1 - 1.2e-05 25.5 35.1 0.0025 18.0 13.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family LOR PF04525.12 PXF45828.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 LURP-one-related HATPase_c PF02518.26 PXF45829.1 - 3.4e-12 46.8 0.0 5.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PXF45829.1 - 0.0011 18.9 0.2 0.0023 17.9 0.2 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 PXF45829.1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain V-ATPase_H_C PF11698.8 PXF45830.1 - 1.1e-22 80.3 0.6 2.8e-22 79.0 0.6 1.7 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 PXF45830.1 - 4.9e-16 58.9 0.4 1e-15 57.9 0.0 1.8 2 1 0 2 2 2 1 V-ATPase subunit H Branch PF02485.21 PXF45831.1 - 1.7e-30 106.4 0.0 2.4e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Putative_PNPOx PF01243.20 PXF45832.1 - 2.9e-12 46.6 0.0 1.2e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 PXF45832.1 - 3.6e-06 27.6 0.0 7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PXF45832.1 - 1.7e-05 25.1 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PXF45832.1 - 0.0042 17.2 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ATG16 PF08614.11 PXF45833.1 - 7.9 6.6 74.4 0.02 15.1 26.1 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPBW PF15180.6 PXF45833.1 - 9.3 6.1 6.9 2.3 8.1 1.1 2.9 1 1 2 3 3 3 0 Neuropeptides B and W ProRS-C_1 PF09180.11 PXF45834.1 - 6.2e-21 74.4 0.2 1.3e-20 73.4 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 PXF45834.1 - 7e-20 71.7 0.0 1.1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PXF45834.1 - 3.7e-14 52.6 0.0 1.4e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain DUF1771 PF08590.10 PXF45834.1 - 0.093 13.1 0.4 0.2 12.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Glt_symporter PF03616.14 PXF45836.1 - 0.0033 16.2 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Sodium/glutamate symporter PRD1_DD PF11087.8 PXF45836.1 - 0.021 14.5 0.2 0.036 13.8 0.2 1.2 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery DUF2946 PF11162.8 PXF45837.1 - 7.4 7.3 8.7 1.9 9.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Cupin_2 PF07883.11 PXF45838.1 - 4.1e-09 36.0 0.0 7.3e-09 35.2 0.0 1.4 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.7 PXF45838.1 - 0.0001 22.1 0.0 0.00012 21.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 PXF45838.1 - 0.00038 20.1 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 PXF45838.1 - 0.017 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HSF_DNA-bind PF00447.17 PXF45840.1 - 2e-28 98.8 0.6 3.7e-28 98.0 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4618 PF15397.6 PXF45840.1 - 0.0075 15.7 1.3 0.013 15.0 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 PXF45840.1 - 0.012 15.7 1.7 0.02 14.9 1.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ets PF00178.22 PXF45840.1 - 0.098 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Ets-domain Cep57_CLD_2 PF14197.6 PXF45840.1 - 0.12 12.4 2.4 0.29 11.2 2.4 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MMR_HSR1 PF01926.23 PXF45841.1 - 2.3e-51 172.7 0.4 8.4e-26 90.3 0.1 2.5 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 PXF45841.1 - 2.5e-31 107.8 0.0 5.2e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 PXF45841.1 - 8.4e-24 83.9 0.0 3.6e-11 42.8 0.0 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 PXF45841.1 - 7.1e-14 51.8 0.5 0.00022 20.8 0.0 5.1 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PXF45841.1 - 4.3e-10 39.9 0.5 0.003 17.6 0.1 3.7 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 PXF45841.1 - 1.8e-08 34.0 0.2 0.0025 17.2 0.2 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 PXF45841.1 - 2.7e-08 33.9 0.8 0.018 15.0 0.0 3.5 3 1 0 3 3 3 2 RsgA GTPase Roc PF08477.13 PXF45841.1 - 2.6e-06 27.7 0.0 0.078 13.2 0.0 3.1 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF45841.1 - 3e-06 26.9 0.0 0.027 14.1 0.0 2.7 2 1 0 2 2 2 2 Ras family ABC_tran PF00005.27 PXF45841.1 - 5.1e-06 27.0 0.0 0.042 14.4 0.1 2.4 2 1 0 2 2 2 2 ABC transporter SRPRB PF09439.10 PXF45841.1 - 6.9e-06 25.6 0.1 0.32 10.4 0.0 3.5 3 1 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PXF45841.1 - 9.7e-06 26.1 0.2 0.015 15.7 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain cobW PF02492.19 PXF45841.1 - 8.7e-05 22.2 0.3 0.025 14.2 0.1 2.8 2 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 PXF45841.1 - 0.00087 18.4 1.1 0.82 8.7 0.0 3.3 4 0 0 4 4 4 1 MCM P-loop domain RNA_helicase PF00910.22 PXF45841.1 - 0.00093 19.6 0.0 0.36 11.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 PXF45841.1 - 0.0012 19.4 0.1 2 8.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PXF45841.1 - 0.002 18.4 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 PXF45841.1 - 0.0023 17.4 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein GBP PF02263.19 PXF45841.1 - 0.003 16.9 0.0 0.55 9.4 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 PXF45841.1 - 0.005 17.1 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 PXF45841.1 - 0.014 14.8 0.4 4.3 6.6 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 PXF45841.1 - 0.016 15.2 0.0 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Septin PF00735.18 PXF45841.1 - 0.021 14.1 0.0 6.1 6.0 0.0 2.7 3 0 0 3 3 3 0 Septin AAA_29 PF13555.6 PXF45841.1 - 0.024 14.4 0.0 9.8 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 PXF45841.1 - 0.024 14.6 0.1 1 9.3 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 PXF45841.1 - 0.04 13.6 0.0 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain L-fibroin PF05849.11 PXF45841.1 - 0.054 12.8 0.3 0.1 11.9 0.3 1.4 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) MeaB PF03308.16 PXF45841.1 - 0.061 12.3 2.5 0.4 9.6 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 PXF45841.1 - 0.075 12.7 0.0 8.4 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PXF45841.1 - 0.1 13.0 0.0 22 5.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 PXF45841.1 - 0.11 12.0 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 PXF45841.1 - 0.16 11.1 1.0 5.8 6.0 0.0 2.8 3 1 0 3 3 3 0 NB-ARC domain ADK PF00406.22 PXF45842.1 - 2.6e-22 79.5 0.0 3.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PXF45842.1 - 2.7e-11 44.0 0.0 4.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PXF45842.1 - 4.6e-05 24.0 0.0 6.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 PXF45843.1 - 4e-20 70.7 3.9 9.6e-05 22.0 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PXF45843.1 - 9.7e-19 65.9 7.0 0.00017 21.4 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 PXF45843.1 - 1.4e-17 62.3 0.4 0.0026 17.9 0.0 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 PXF45843.1 - 2.3e-15 56.0 1.0 9.7e-05 22.0 0.1 5.1 3 1 2 5 5 5 2 TPR repeat TPR_17 PF13431.6 PXF45843.1 - 1e-11 44.4 0.3 0.00075 19.7 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF45843.1 - 9.8e-11 41.6 8.4 0.00056 20.5 0.1 6.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PXF45843.1 - 2.8e-10 39.5 4.8 0.006 16.5 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF45843.1 - 3.9e-09 37.0 8.5 0.00024 21.7 0.4 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF45843.1 - 9.4e-09 35.4 7.0 0.00063 20.0 0.2 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 PXF45843.1 - 1.6e-05 24.6 9.3 0.013 15.3 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.17 PXF45843.1 - 0.00037 21.0 2.0 0.26 11.7 0.1 3.6 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 PXF45843.1 - 0.00039 20.9 3.4 2.5 8.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF45843.1 - 0.00099 18.4 3.0 0.13 11.5 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 PXF45843.1 - 0.0026 17.8 1.6 6.5 6.9 0.0 4.4 6 0 0 6 6 5 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 PXF45843.1 - 0.004 17.3 9.1 0.036 14.2 0.1 4.8 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF45843.1 - 0.0069 16.9 1.2 0.68 10.5 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 PXF45843.1 - 0.053 13.8 0.3 13 6.2 0.1 3.9 2 2 2 4 4 4 0 Tetratricopeptide repeat AA_kinase PF00696.28 PXF45844.1 - 1.2e-45 156.0 0.0 1.6e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 PXF45844.1 - 1.2e-08 34.6 5.0 4.9e-05 23.0 0.6 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 PXF45844.1 - 2.9e-07 30.1 1.1 0.016 15.0 0.2 2.7 2 0 0 2 2 2 2 ACT domain Archease PF01951.16 PXF45844.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) Trypsin PF00089.26 PXF45845.1 - 1.5e-36 126.3 0.3 2.7e-36 125.4 0.3 1.5 1 0 0 1 1 1 1 Trypsin Protocadherin PF08374.11 PXF45845.1 - 0.032 14.2 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 Protocadherin Pribosyltran PF00156.27 PXF45845.1 - 0.15 11.6 1.0 0.35 10.4 1.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Trypsin PF00089.26 PXF45846.1 - 9.9e-41 140.0 0.0 1.5e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin SPC12 PF06645.13 PXF45846.1 - 3.2 7.9 4.7 1 9.5 0.8 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) bZIP_1 PF00170.21 PXF45848.1 - 3.2e-09 36.7 12.3 3.2e-09 36.7 12.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF45848.1 - 4.3e-05 23.5 11.4 4.3e-05 23.5 11.4 2.6 1 1 1 2 2 2 1 Basic region leucine zipper FAM76 PF16046.5 PXF45848.1 - 8.2 5.7 13.2 12 5.1 13.2 1.2 1 0 0 1 1 1 0 FAM76 protein Trypsin PF00089.26 PXF45850.1 - 1.4e-41 142.7 0.0 2.1e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Acetyltransf_1 PF00583.25 PXF45851.1 - 9e-13 48.5 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF45851.1 - 1.8e-12 47.3 0.1 3.6e-12 46.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF45851.1 - 1.1e-09 38.6 0.0 1.6e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF45851.1 - 7.8e-06 26.6 0.0 1.2e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF45851.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PXF45851.1 - 0.00093 19.3 0.2 0.0079 16.3 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PXF45851.1 - 0.0023 18.0 0.1 0.0056 16.8 0.1 1.8 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 PXF45851.1 - 0.0058 16.1 0.3 0.011 15.2 0.3 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_8 PF13523.6 PXF45851.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA_Me_trans PF03054.16 PXF45853.1 - 8.9e-109 363.5 0.0 1.1e-108 363.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.15 PXF45853.1 - 5e-17 61.9 0.0 8e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Asn_synthase PF00733.21 PXF45853.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 PXF45853.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 PXF45853.1 - 0.17 11.0 0.0 0.82 8.7 0.0 2.1 2 1 0 2 2 2 0 NAD synthase CPSF_A PF03178.15 PXF45854.1 - 5.4e-47 160.7 0.1 1.4e-46 159.4 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 PXF45854.1 - 6e-21 74.6 0.1 9.8e-10 37.7 0.1 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Rap1_C PF11626.8 PXF45854.1 - 0.1 12.7 0.9 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain YabA PF06156.13 PXF45855.1 - 0.02 15.5 1.8 0.023 15.3 1.8 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Snapin_Pallidin PF14712.6 PXF45855.1 - 0.08 13.4 2.3 0.13 12.7 2.1 1.6 1 1 0 1 1 1 0 Snapin/Pallidin FH2 PF02181.23 PXF45856.1 - 7.7e-13 48.3 0.3 8.5e-13 48.2 0.3 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DNA_pol_B PF00136.21 PXF45857.1 - 9.2e-42 143.3 0.0 1.1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DUF1908 PF08926.11 PXF45857.1 - 0.0047 16.0 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) BDV_P24 PF06595.11 PXF45857.1 - 0.032 14.1 0.1 0.057 13.3 0.1 1.4 1 1 0 1 1 1 0 Borna disease virus P24 protein Hint PF01079.20 PXF45858.1 - 1.9e-07 30.8 0.0 1.9e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Hint module DUF2160 PF09928.9 PXF45858.1 - 0.023 15.0 0.3 0.025 14.9 0.3 1.1 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) PEARLI-4 PF05278.12 PXF45858.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Costars PF14705.6 PXF45864.1 - 6.8e-24 83.8 0.7 7.4e-24 83.7 0.7 1.0 1 0 0 1 1 1 1 Costars zf-MYND PF01753.18 PXF45865.1 - 0.029 14.5 0.6 0.067 13.3 0.6 1.6 1 0 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 PXF45865.1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Patatin PF01734.22 PXF45866.1 - 6e-29 101.7 0.0 2.4e-28 99.7 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase EIIA-man PF03610.16 PXF45866.1 - 0.0091 16.2 0.9 0.34 11.2 0.4 2.8 3 0 0 3 3 3 1 PTS system fructose IIA component Glyco_hydro_35 PF01301.19 PXF45867.1 - 4.9e-81 272.8 0.0 7e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Abhydrolase_1 PF00561.20 PXF45868.1 - 1.9e-21 76.9 1.0 6.6e-16 58.7 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF45868.1 - 2.1e-10 41.6 10.1 1.9e-09 38.4 0.1 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF45868.1 - 8.9e-09 35.0 0.0 2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 GRAM PF02893.20 PXF45868.1 - 0.00016 21.5 0.3 0.0014 18.5 0.3 2.2 1 1 0 1 1 1 1 GRAM domain Abhydrolase_4 PF08386.10 PXF45868.1 - 0.0034 17.5 0.0 0.0098 16.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Pkinase PF00069.25 PXF45869.1 - 1.2e-58 198.6 0.0 1.6e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45869.1 - 9.9e-29 100.4 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45869.1 - 8.1e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF45869.1 - 0.0024 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF45869.1 - 0.012 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PMT PF02366.18 PXF45870.1 - 3.7e-29 102.0 14.1 3.7e-29 102.0 14.1 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PXF45870.1 - 1.4e-27 96.6 13.2 1.4e-27 96.6 13.2 3.0 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMP22_Claudin PF00822.20 PXF45870.1 - 0.003 17.5 4.5 0.0048 16.8 0.1 2.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Ctr PF04145.15 PXF45870.1 - 5.6 7.6 9.4 6.1 7.5 0.1 3.2 3 1 0 3 3 3 0 Ctr copper transporter family Peptidase_A24 PF01478.18 PXF45871.1 - 0.24 11.8 7.0 0.52 10.7 7.0 1.6 1 1 0 1 1 1 0 Type IV leader peptidase family TssO PF17561.2 PXF45871.1 - 0.34 11.0 0.6 12 6.0 0.0 2.4 2 1 0 2 2 2 0 Type VI secretion system, TssO Pkinase PF00069.25 PXF45873.1 - 6.2e-67 225.7 0.0 9.1e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45873.1 - 2.5e-37 128.6 0.0 1.3e-23 83.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PXF45873.1 - 2.3e-06 27.1 0.0 0.00031 20.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like FTA2 PF13095.6 PXF45873.1 - 0.021 14.5 0.0 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH PF00169.29 PXF45873.1 - 0.032 14.7 0.0 0.088 13.3 0.0 1.7 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 PXF45873.1 - 0.043 12.8 0.8 0.16 10.9 0.2 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Na_sulph_symp PF00939.19 PXF45874.1 - 5.5e-22 78.4 30.7 8.4e-22 77.9 30.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 PXF45874.1 - 1.5e-20 74.5 11.9 5.7e-14 52.8 0.1 2.9 1 1 0 2 2 2 2 SPX domain CitMHS PF03600.16 PXF45874.1 - 5.8e-18 65.1 43.4 1.2e-10 41.1 16.7 2.8 1 1 2 3 3 3 2 Citrate transporter DUF2933 PF11666.8 PXF45874.1 - 2.9 8.0 6.4 10 6.2 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) GYF PF02213.16 PXF45876.1 - 3.3e-13 49.1 0.3 6.3e-13 48.2 0.3 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 PXF45876.1 - 0.024 14.5 0.5 0.089 12.6 0.1 2.3 2 0 0 2 2 2 0 GYF domain 2 Methyltransf_32 PF13679.6 PXF45878.1 - 6.1e-19 68.6 0.7 6.8e-18 65.2 0.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PXF45878.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Peptidase_C97 PF05903.14 PXF45879.1 - 1.4e-38 132.1 0.0 2.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 PXF45879.1 - 1.4e-16 60.6 0.9 2.7e-15 56.4 0.9 2.1 1 1 0 1 1 1 1 PUL domain HEAT_2 PF13646.6 PXF45879.1 - 0.068 13.6 0.1 0.2 12.1 0.1 1.8 1 0 0 1 1 1 0 HEAT repeats ERM PF00769.19 PXF45880.1 - 0.016 15.1 30.7 0.024 14.5 30.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BUD22 PF09073.10 PXF45880.1 - 0.064 12.6 20.6 0.086 12.2 20.6 1.1 1 0 0 1 1 1 0 BUD22 ALMT PF11744.8 PXF45880.1 - 0.29 9.9 18.1 0.44 9.3 18.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2157 PF09925.9 PXF45880.1 - 0.36 10.6 4.1 1.2 8.9 3.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) MutS_III PF05192.18 PXF45880.1 - 0.38 11.0 7.1 0.61 10.3 7.1 1.4 1 0 0 1 1 1 0 MutS domain III Peptidase_S46 PF10459.9 PXF45880.1 - 0.49 9.0 13.3 0.69 8.5 13.3 1.1 1 0 0 1 1 1 0 Peptidase S46 MIEAP PF16026.5 PXF45880.1 - 1.4 9.1 11.1 2.5 8.3 11.1 1.4 1 0 0 1 1 1 0 Mitochondria-eating protein Atg14 PF10186.9 PXF45880.1 - 3.3 6.7 20.9 6.6 5.7 20.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 PXF45881.1 - 0.023 14.8 1.8 0.15 12.1 0.7 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 PXF45881.1 - 0.054 13.1 7.5 0.087 12.4 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3919 PF13057.6 PXF45881.1 - 0.079 12.5 2.4 0.17 11.5 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3919) LPD5 PF18799.1 PXF45881.1 - 0.095 13.1 2.8 0.18 12.2 2.8 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 DUF724 PF05266.14 PXF45881.1 - 0.43 10.4 12.6 0.87 9.4 11.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3981 PF13139.6 PXF45881.1 - 0.58 10.6 2.7 1.1 9.7 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3981) Streptin-Immun PF11083.8 PXF45881.1 - 1.2 9.6 5.2 14 6.2 2.0 2.4 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein IKKbetaNEMObind PF12179.8 PXF45881.1 - 1.5 8.9 3.4 37 4.5 0.1 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Spc7 PF08317.11 PXF45881.1 - 2.2 7.1 20.2 5.9 5.7 0.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Retrotran_gag_2 PF14223.6 PXF45882.1 - 0.0017 18.0 0.1 0.0059 16.3 0.1 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2278 PF10042.9 PXF45882.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) DUF5535 PF17687.1 PXF45882.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Pkinase PF00069.25 PXF45883.1 - 1.1e-57 195.5 0.0 1.5e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45883.1 - 5.7e-32 111.0 0.0 8.8e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF45883.1 - 1.8e-09 37.3 0.0 8.3e-09 35.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF45883.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF45883.1 - 0.041 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PXF45883.1 - 0.057 13.3 1.7 0.24 11.3 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DRIM PF07539.12 PXF45884.1 - 1.7e-25 89.4 9.2 3.2e-17 62.1 0.1 5.7 5 1 1 6 6 6 3 Down-regulated in metastasis HEAT_2 PF13646.6 PXF45884.1 - 0.00025 21.4 9.3 5.8 7.4 0.1 6.6 5 0 0 5 5 5 3 HEAT repeats IFRD PF05004.13 PXF45884.1 - 0.00041 19.5 15.4 0.012 14.8 0.5 4.6 6 0 0 6 6 6 2 Interferon-related developmental regulator (IFRD) PUL PF08324.11 PXF45884.1 - 0.011 15.0 0.0 2.8 7.1 0.0 3.5 2 0 0 2 2 2 0 PUL domain HEAT PF02985.22 PXF45884.1 - 0.027 14.7 11.7 1.7 9.1 0.0 7.4 8 0 0 8 8 8 0 HEAT repeat Med19 PF10278.9 PXF45884.1 - 0.028 14.4 5.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Pet127 PF08634.10 PXF45884.1 - 0.12 11.7 0.1 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial protein Pet127 DAO PF01266.24 PXF45885.1 - 1.4e-59 202.5 0.2 1.9e-59 202.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF45885.1 - 9.3e-05 22.6 0.4 0.00025 21.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PXF45885.1 - 0.00014 21.3 0.6 0.39 9.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 PXF45885.1 - 0.00022 20.5 0.2 0.027 13.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF45885.1 - 0.021 15.4 0.5 0.065 13.8 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 PXF45885.1 - 0.03 12.9 0.0 0.23 9.9 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 PXF45885.1 - 0.18 10.9 0.8 0.23 10.5 0.8 1.4 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 PXF45885.1 - 0.31 10.2 2.0 0.29 10.3 0.9 1.5 2 0 0 2 2 2 0 FAD binding domain Pox_MCEL PF03291.16 PXF45886.1 - 5.6e-82 275.5 0.4 8.4e-82 274.9 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 PXF45886.1 - 1e-10 42.1 0.2 2.5e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF45886.1 - 6.7e-07 29.9 0.1 1.2e-06 29.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF45886.1 - 2.6e-05 24.1 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF45886.1 - 3.6e-05 24.4 0.0 0.00031 21.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF45886.1 - 0.00099 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF45886.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 PXF45886.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TPMT PF05724.11 PXF45886.1 - 0.024 14.3 0.0 0.047 13.3 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CBFB_NFYA PF02045.15 PXF45887.1 - 1.7e-21 76.6 7.4 2.4e-21 76.1 7.4 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TRAPP PF04051.16 PXF45888.1 - 6.5e-32 110.3 0.0 7.6e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component V4R PF02830.18 PXF45888.1 - 0.087 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 V4R domain PAPS_reduct PF01507.19 PXF45890.1 - 7.3e-44 149.9 0.0 1.1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 PXF45890.1 - 1.3e-17 63.7 0.9 5.1e-17 61.9 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin_2 PF13098.6 PXF45890.1 - 0.0033 17.8 0.1 0.0093 16.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.6 PXF45890.1 - 0.062 13.7 0.0 0.34 11.4 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 PXF45890.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Helicase_C PF00271.31 PXF45891.1 - 6e-23 81.3 0.0 1.4e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF45892.1 - 9.7e-44 149.2 0.0 1.2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 PXF45892.1 - 1e-12 48.2 0.1 1.6e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 SPRY domain ResIII PF04851.15 PXF45892.1 - 0.13 12.2 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FeThRed_A PF02941.15 PXF45894.1 - 1.9e-22 79.2 0.2 2.4e-22 78.9 0.2 1.1 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain SAVED PF18145.1 PXF45894.1 - 0.099 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain PAP2 PF01569.21 PXF45895.1 - 0.092 12.5 0.0 0.27 11.0 0.0 1.7 1 1 0 1 1 1 0 PAP2 superfamily HSP70 PF00012.20 PXF45897.1 - 2e-256 851.9 18.2 2.5e-256 851.6 18.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PXF45897.1 - 2.4e-18 66.0 1.1 6e-17 61.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 PXF45897.1 - 0.00054 19.7 0.0 0.0033 17.2 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PXF45897.1 - 0.0012 18.2 1.3 0.074 12.3 0.1 2.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.6 PXF45897.1 - 0.083 13.3 9.2 4.5 7.8 0.4 3.8 3 2 0 3 3 3 0 Cell division protein FtsA DUF1464 PF07318.12 PXF45897.1 - 2.6 7.1 7.6 1.6 7.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1464) UPF0242 PF06785.11 PXF45897.1 - 8.3 6.5 16.2 0.54 10.3 10.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L1 PF00687.21 PXF45898.1 - 6.4e-48 163.2 0.0 1e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF2_N PF00176.23 PXF45901.1 - 2.9e-56 190.7 0.0 4.2e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF45901.1 - 2.1e-06 28.0 0.0 5.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 PXF45901.1 - 0.0068 16.2 7.5 0.0068 16.2 7.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PXF45901.1 - 0.0072 16.2 6.1 0.018 14.9 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 PXF45901.1 - 0.026 14.5 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 PXF45901.1 - 0.18 11.7 7.1 0.38 10.7 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF45901.1 - 1.6 8.6 5.7 4.2 7.3 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IML1 PF12257.8 PXF45902.1 - 0.0034 16.6 0.2 0.0082 15.3 0.1 1.6 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 Hemerythrin PF01814.23 PXF45902.1 - 2.5 8.8 7.1 2.1 9.0 0.4 2.7 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Hemerythrin PF01814.23 PXF45903.1 - 0.0059 17.2 2.2 0.11 13.1 2.7 2.4 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF1127 PF06568.11 PXF45903.1 - 3.7 7.4 6.5 12 5.7 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Sel1 PF08238.12 PXF45904.1 - 4.5e-24 84.3 4.5 0.00016 22.2 0.0 11.1 12 0 0 12 12 12 6 Sel1 repeat HSP20 PF00011.21 PXF45904.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family ANAPC3 PF12895.7 PXF45904.1 - 0.13 12.5 5.2 5.6 7.3 0.0 4.7 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF45904.1 - 0.14 12.2 7.2 58 4.1 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 PXF45905.1 - 1.7e-11 43.7 0.2 2.6e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FAD_binding_4 PF01565.23 PXF45906.1 - 9.4e-26 90.2 0.4 1.4e-17 63.7 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Glyco_transf_11 PF01531.16 PXF45908.1 - 8e-10 38.4 0.0 5.8e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 11 UQ_con PF00179.26 PXF45909.1 - 1.2e-19 70.4 0.0 1.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sulfotransfer_2 PF03567.14 PXF45909.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family DUF5383 PF17355.2 PXF45909.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) PsaM PF07465.13 PXF45909.1 - 0.37 10.5 1.7 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Fip1 PF05182.13 PXF45910.1 - 1.7e-19 69.0 0.6 3.9e-19 67.9 0.6 1.6 1 0 0 1 1 1 1 Fip1 motif EBV-NA3 PF05009.12 PXF45910.1 - 2.6 7.5 9.1 45 3.4 0.0 2.4 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PPL5 PF18168.1 PXF45910.1 - 2.8 7.2 5.2 5.4 6.2 5.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 tRNA_edit PF04073.15 PXF45911.1 - 2.5e-06 27.6 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Aminoacyl-tRNA editing domain Sec1 PF00995.23 PXF45912.1 - 1.4e-105 354.7 0.0 1.6e-105 354.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Dymeclin PF09742.9 PXF45913.1 - 9e-42 143.3 0.0 3.4e-41 141.4 0.0 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 PXF45913.1 - 0.00014 20.2 1.4 0.00017 19.9 0.0 1.8 3 0 0 3 3 3 1 High-temperature-induced dauer-formation protein FAD_binding_6 PF00970.24 PXF45914.1 - 1.3e-11 44.7 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PXF45914.1 - 8.4e-11 42.5 0.0 1.2e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain COMMD1_N PF17221.3 PXF45914.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 COMMD1 N-terminal domain DUF410 PF04190.13 PXF45915.1 - 8.6e-46 156.8 0.0 2.3e-45 155.4 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF410) Porin_3 PF01459.22 PXF45916.1 - 5.6e-28 98.2 2.8 4.4e-27 95.2 2.8 1.9 1 1 0 1 1 1 1 Eukaryotic porin ADP_ribosyl_GH PF03747.14 PXF45918.1 - 0.0041 16.9 0.1 0.0044 16.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase bHLH-MYC_N PF14215.6 PXF45919.1 - 1.8e-07 31.6 0.2 1.6e-06 28.5 0.2 2.2 1 1 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.6 PXF45919.1 - 1.6e-05 25.3 0.0 3.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PXF45919.1 - 1.7e-05 25.4 0.0 3.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain HLH PF00010.26 PXF45919.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SCAB-PH PF17684.1 PXF45920.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein UCR_Fe-S_N PF10399.9 PXF45920.1 - 0.14 11.5 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF1298 PF06974.13 PXF45921.1 - 1.5e-25 89.9 0.0 2.2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 PXF45921.1 - 2.3e-09 37.4 0.0 9.5e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 PXF45921.1 - 0.0073 15.0 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 Condensation domain RVT_2 PF07727.14 PXF45923.1 - 1.5e-13 51.0 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Amino_oxidase PF01593.24 PXF45927.1 - 1.5e-52 179.4 0.1 1.8e-52 179.2 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF45927.1 - 4.7e-16 58.8 0.8 9.7e-16 57.8 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF45927.1 - 0.00022 20.9 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF45927.1 - 0.00087 18.6 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PXF45927.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 PXF45927.1 - 0.0078 15.3 0.0 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 PXF45927.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 PXF45927.1 - 0.0096 16.5 0.0 0.03 14.9 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF45927.1 - 0.016 15.2 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 PXF45927.1 - 0.017 13.8 0.0 0.041 12.6 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 PXF45927.1 - 0.021 13.9 0.6 0.037 13.1 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 PXF45927.1 - 0.2 10.7 0.1 0.35 9.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A VWA_2 PF13519.6 PXF45929.1 - 6.2e-08 33.2 0.0 3.2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PXF45929.1 - 1.6e-05 25.3 0.0 5.1e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Nitr_red_bet_C PF14711.6 PXF45929.1 - 0.065 12.9 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal Alkyl_sulf_dimr PF14863.6 PXF45930.1 - 3.7e-55 186.2 2.9 7.3e-55 185.2 2.9 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 PXF45930.1 - 1.9e-33 116.2 0.0 2.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 PXF45930.1 - 1.3e-27 96.5 0.9 2.2e-27 95.8 0.9 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 PXF45930.1 - 6.9e-07 29.0 0.0 2.2e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TPR_19 PF14559.6 PXF45930.1 - 0.13 12.8 0.4 0.32 11.5 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 PXF45931.1 - 3.3e-28 98.1 0.0 4.6e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF45931.1 - 3.8e-18 65.6 0.0 1.1e-16 60.8 0.0 2.1 1 1 0 1 1 1 1 Redoxin 5HT_transport_N PF03491.13 PXF45932.1 - 0.3 11.3 0.2 0.3 11.3 0.2 2.0 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Connexin PF00029.19 PXF45932.1 - 5.3 6.7 6.2 9.7 5.9 6.2 1.3 1 0 0 1 1 1 0 Connexin FAD_binding_4 PF01565.23 PXF45935.1 - 2.4e-28 98.6 0.0 8e-19 67.8 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 PXF45935.1 - 0.0017 18.4 0.1 0.0042 17.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like PEMT PF04191.13 PXF45936.1 - 1.7e-13 50.9 0.0 2.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 PXF45936.1 - 1.2e-06 28.8 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 PXF45936.1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 PXF45936.1 - 0.00041 19.9 0.2 0.00058 19.4 0.2 1.2 1 0 0 1 1 1 1 NnrU protein Steroid_dh PF02544.16 PXF45936.1 - 0.007 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PXF45936.1 - 0.093 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PAC4 PF16093.5 PXF45937.1 - 2e-10 40.7 0.6 2.8e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Cation_ATPase_C PF00689.21 PXF45938.1 - 0.016 15.0 0.7 0.82 9.4 0.9 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Trp_oprn_chp PF09534.10 PXF45938.1 - 0.037 13.8 2.0 6.4 6.5 0.0 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4079 PF13301.6 PXF45938.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) EphA2_TM PF14575.6 PXF45938.1 - 0.35 11.8 1.2 1.4 9.9 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Tetraspanin PF00335.20 PXF45938.1 - 0.64 9.7 1.5 18 4.9 0.0 2.2 2 0 0 2 2 2 0 Tetraspanin family ABC1 PF03109.16 PXF45939.1 - 3.8e-32 110.9 0.1 6.8e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PXF45939.1 - 3.4e-07 30.5 1.7 0.00013 22.0 0.3 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 PXF45939.1 - 0.00032 20.2 0.1 0.12 11.7 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain WaaY PF06176.11 PXF45939.1 - 0.048 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Ribosomal_S2 PF00318.20 PXF45940.1 - 1.5e-53 181.2 0.1 8.9e-30 103.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 FAD_binding_7 PF03441.14 PXF45941.1 - 1.2e-51 175.1 0.0 1.8e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PXF45941.1 - 1.7e-28 99.7 0.0 2.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Trypsin PF00089.26 PXF45942.1 - 1.4e-17 64.3 0.0 3.6e-17 62.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin Glycos_transf_2 PF00535.26 PXF45943.1 - 1.4e-21 77.1 0.0 1.6e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF45943.1 - 1.3e-08 35.1 0.0 1.5e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF45943.1 - 0.00012 21.6 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PXF45943.1 - 0.00084 19.8 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 TMEM173 PF15009.6 PXF45943.1 - 0.09 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 TSC22 PF01166.18 PXF45944.1 - 0.078 13.3 0.3 0.21 11.9 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Fer4_24 PF18109.1 PXF45944.1 - 1.3 9.4 3.9 2.6 8.4 0.3 3.1 4 0 0 4 4 4 0 Ferredoxin I 4Fe-4S cluster domain RNA_pol_Rpb1_3 PF04983.18 PXF45946.1 - 2.7e-43 147.6 0.0 4.4e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 PXF45946.1 - 7.7e-42 143.3 0.7 7.6e-41 140.1 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 PXF45946.1 - 9.5e-32 109.2 0.1 2.4e-31 107.9 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 4 DNA_ligase_aden PF01653.18 PXF45947.1 - 1.5e-48 165.5 0.0 1.6e-47 162.1 0.0 2.0 1 1 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PXF45948.1 - 1.9e-13 50.1 0.1 1.3e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_5 PF14520.6 PXF45948.1 - 7.3e-05 23.3 0.0 0.012 16.3 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 PXF45948.1 - 0.00052 20.1 0.2 0.014 15.4 0.0 2.8 2 1 0 2 2 2 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 PXF45948.1 - 0.14 12.0 0.1 38 4.1 0.0 3.3 2 1 1 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain Beta_propel PF09826.9 PXF45954.1 - 3.1e-122 409.1 0.0 3.6e-122 408.9 0.0 1.0 1 0 0 1 1 1 1 Beta propeller domain FPL PF09758.9 PXF45955.1 - 0.056 13.4 0.7 0.083 12.9 0.7 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein EzrA PF06160.12 PXF45956.1 - 0.023 12.9 2.7 0.031 12.5 2.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF45956.1 - 0.024 14.9 1.1 0.59 10.4 0.0 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF45956.1 - 4.2 8.1 13.8 0.74 10.5 6.8 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Plant_tran PF04827.14 PXF45957.1 - 3.9e-52 176.8 0.0 5.8e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF45957.1 - 1.5e-12 47.4 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H2-Ydr279 PF09468.10 PXF45957.1 - 0.04 14.1 0.0 0.094 12.9 0.0 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Carb_anhydrase PF00194.21 PXF45959.1 - 9e-27 94.2 0.0 2.6e-26 92.7 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Retrotran_gag_2 PF14223.6 PXF45964.1 - 2.5e-09 36.9 0.0 3.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 PXF45964.1 - 0.052 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 PXF45964.1 - 0.084 13.0 5.8 0.15 12.2 4.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.17 PXF45966.1 - 7.1e-05 23.0 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein PTSIIB_sorb PF03830.15 PXF45966.1 - 0.055 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component SSTK-IP PF15836.5 PXF45966.1 - 3.8 7.7 7.3 9.5 6.4 0.4 3.1 4 0 0 4 4 4 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein BATS PF06968.13 PXF45967.1 - 7.6e-05 22.8 0.0 1.7 8.8 0.0 3.6 3 1 2 5 5 5 2 Biotin and Thiamin Synthesis associated domain zf-C3HC4_5 PF17121.5 PXF45967.1 - 0.0031 17.4 2.4 41 4.2 0.0 4.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF2203 PF09969.9 PXF45967.1 - 0.0047 17.6 0.5 72 4.1 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) dsRBD2 PF17842.1 PXF45967.1 - 0.027 14.7 0.0 42 4.3 0.0 3.5 4 0 0 4 4 4 0 Double-stranded RNA binding domain 2 zf-ANAPC11 PF12861.7 PXF45967.1 - 0.092 12.8 11.0 25 5.0 0.2 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 PXF45967.1 - 0.24 11.0 17.5 7.8 6.2 0.4 4.4 4 0 0 4 4 4 0 RecR protein Shadoo PF14999.6 PXF45967.1 - 0.37 10.9 11.7 9.9 6.3 0.5 4.3 1 1 0 4 4 4 0 Shadow of prion protein, neuroprotective DUF630 PF04783.12 PXF45967.1 - 0.78 10.0 4.7 1.9e+02 2.3 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF630) ZZ PF00569.17 PXF45967.1 - 1.8 8.4 19.3 18 5.3 0.5 4.4 4 0 0 4 4 4 0 Zinc finger, ZZ type Peptidase_M15 PF01427.17 PXF45968.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase SieB PF14163.6 PXF45968.1 - 0.13 11.7 0.4 0.38 10.2 0.1 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3995 PF13160.6 PXF45968.1 - 0.18 12.1 2.2 0.54 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) HalX PF08663.10 PXF45968.1 - 0.69 10.3 4.9 1.1 9.6 0.5 2.7 2 0 0 2 2 2 0 HalX domain Phage_holin_3_6 PF07332.11 PXF45969.1 - 0.00013 21.9 3.6 0.0002 21.4 3.6 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SseC PF04888.12 PXF45969.1 - 0.00029 20.5 2.9 0.0004 20.1 2.9 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ABC_membrane PF00664.23 PXF45969.1 - 0.0041 16.8 0.1 0.0054 16.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region EzrA PF06160.12 PXF45969.1 - 0.0067 14.7 0.3 0.0098 14.1 0.3 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TetR PF13972.6 PXF45969.1 - 0.063 13.0 0.2 0.18 11.5 0.1 1.7 1 1 1 2 2 2 0 Bacterial transcriptional repressor DUF2207 PF09972.9 PXF45969.1 - 0.064 12.0 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Med22 PF06179.12 PXF45969.1 - 0.067 13.4 1.1 0.13 12.4 0.3 1.9 2 1 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex Sec23_trunk PF04811.15 PXF45969.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain TraG_N PF07916.11 PXF45969.1 - 8.1 5.2 9.2 4.8 5.9 6.2 1.8 1 1 1 2 2 2 0 TraG-like protein, N-terminal region FemAB_like PF04339.12 PXF45970.1 - 0.013 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Hemocyanin_C PF03723.14 PXF45970.1 - 0.041 13.2 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, ig-like domain DLP_helical PF18709.1 PXF45972.1 - 0.04 13.1 4.0 0.15 11.2 0.3 2.9 2 1 0 3 3 3 0 Dynamin-like helical domain PhoU PF01895.19 PXF45972.1 - 0.47 10.9 2.7 16 6.0 0.3 3.5 2 2 0 2 2 2 0 PhoU domain LigB PF02900.18 PXF45974.1 - 5.5e-37 127.3 0.0 6.5e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase ACT PF01842.25 PXF45974.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ACT domain HemolysinCabind PF00353.19 PXF45975.1 - 7e-12 45.1 21.1 2.1e-08 34.0 7.0 7.8 7 1 0 8 8 8 2 RTX calcium-binding nonapeptide repeat (4 copies) SPACA9 PF15120.6 PXF45976.1 - 0.025 14.4 0.1 0.028 14.2 0.1 1.1 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 KH_6 PF15985.5 PXF45977.1 - 0.0018 18.6 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 KH domain VPS13 PF16908.5 PXF45980.1 - 8.9e-09 35.5 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PXF45982.1 - 0.047 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 Pkinase PF00069.25 PXF45983.1 - 2.4e-60 204.1 0.0 4.8e-60 203.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF45983.1 - 1.2e-28 100.1 0.0 1.8e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF45983.1 - 7.3e-05 21.7 0.2 0.00016 20.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PXF45983.1 - 0.00011 21.6 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PXF45983.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PXF45983.1 - 0.046 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bax1-I PF01027.20 PXF45985.1 - 1.3e-31 110.1 39.2 1.5e-21 77.2 31.2 2.2 2 0 0 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Adenine_glyco PF03352.13 PXF45986.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase TcdA_TcdB PF12919.7 PXF45986.1 - 0.17 11.2 0.1 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain TcdA_TcdB PF12919.7 PXF45987.1 - 0.1 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Filament PF00038.21 PXF45988.1 - 0.00018 21.2 4.5 0.059 13.0 1.1 2.1 2 0 0 2 2 2 2 Intermediate filament protein Spc7 PF08317.11 PXF45988.1 - 0.00024 20.1 7.1 0.16 10.8 4.1 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Rab5-bind PF09311.11 PXF45988.1 - 0.015 14.7 10.4 0.034 13.5 1.4 2.9 2 1 1 3 3 3 0 Rabaptin-like protein CortBP2 PF09727.9 PXF45988.1 - 0.05 13.5 13.6 0.26 11.2 12.0 2.2 1 1 1 2 2 2 0 Cortactin-binding protein-2 Macoilin PF09726.9 PXF45988.1 - 0.071 11.7 13.2 0.37 9.3 0.9 2.0 1 1 1 2 2 2 0 Macoilin family Jnk-SapK_ap_N PF09744.9 PXF45988.1 - 0.075 13.2 11.8 0.59 10.3 5.1 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_23 PF13476.6 PXF45988.1 - 0.092 13.2 2.0 0.13 12.7 2.0 1.3 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 PXF45988.1 - 0.22 11.3 11.9 0.05 13.4 4.0 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 CENP-Q PF13094.6 PXF45988.1 - 0.26 11.5 11.7 0.12 12.6 5.4 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF745 PF05335.13 PXF45988.1 - 0.29 10.9 28.1 0.3 10.8 4.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 PXF45988.1 - 0.39 10.7 16.0 3.2 7.8 2.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 PXF45988.1 - 0.48 9.9 20.4 0.77 9.3 3.7 2.7 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Cluap1 PF10234.9 PXF45988.1 - 0.55 9.6 7.5 0.72 9.2 2.3 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 FliJ PF02050.16 PXF45988.1 - 0.75 10.0 15.4 0.86 9.8 3.0 3.0 1 1 3 4 4 4 0 Flagellar FliJ protein Tropomyosin_1 PF12718.7 PXF45988.1 - 0.89 9.7 15.0 0.29 11.3 4.4 2.9 2 1 1 3 3 3 0 Tropomyosin like Sec8_exocyst PF04048.14 PXF45988.1 - 0.96 9.3 9.2 0.76 9.7 1.2 2.8 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain CREPT PF16566.5 PXF45988.1 - 1.4 9.1 8.0 1.8 8.7 1.6 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CwsA PF10814.8 PXF45988.1 - 1.7 8.9 8.3 3.2 7.9 4.6 2.4 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA Atg14 PF10186.9 PXF45988.1 - 1.8 7.5 9.6 2.6 7.1 0.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 PXF45988.1 - 2 6.3 9.3 1.1 7.2 0.6 2.0 2 0 0 2 2 2 0 Prominin Selenoprotein_S PF06936.11 PXF45988.1 - 2.1 8.1 6.1 1 9.1 1.8 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) ADIP PF11559.8 PXF45988.1 - 2.2 8.4 16.8 1.7 8.7 3.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cauli_AT PF03233.13 PXF45988.1 - 2.3 8.1 6.7 1.5 8.7 1.9 2.1 2 0 0 2 2 2 0 Aphid transmission protein Tho2 PF11262.8 PXF45988.1 - 2.4 7.3 6.9 2.7 7.1 0.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4398 PF14346.6 PXF45988.1 - 2.5 8.8 13.2 0.11 13.2 6.6 2.2 3 0 0 3 3 1 0 Domain of unknown function (DUF4398) DUF724 PF05266.14 PXF45988.1 - 2.6 7.8 10.3 30 4.4 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 PXF45988.1 - 2.9 8.4 14.6 2 9.0 2.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4164 PF13747.6 PXF45988.1 - 3 8.2 10.3 12 6.3 6.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Bud13 PF09736.9 PXF45988.1 - 3.1 8.2 6.5 19 5.6 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Laminin_II PF06009.12 PXF45988.1 - 3.1 7.8 15.9 4.4 7.3 6.2 2.3 2 0 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 PXF45988.1 - 3.3 8.2 7.6 3.4 8.2 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ALMT PF11744.8 PXF45988.1 - 3.5 6.4 9.4 4.7 5.9 9.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FOXP-CC PF16159.5 PXF45988.1 - 3.6 8.3 8.9 4.6 7.9 1.3 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF948 PF06103.11 PXF45988.1 - 3.6 7.9 10.1 1.6 9.0 1.1 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 PXF45988.1 - 4.7 7.5 15.8 13 6.0 8.4 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 PXF45988.1 - 4.9 7.8 17.8 6.4 7.4 4.4 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF2408 PF10303.9 PXF45988.1 - 5.9 7.5 8.5 5.2 7.6 4.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) COG2 PF06148.11 PXF45988.1 - 6.1 6.9 11.4 17 5.5 0.2 3.8 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 PXF45988.1 - 7.5 7.1 11.8 17 6.0 6.0 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 PXF45989.1 - 0.031 14.3 0.7 0.031 14.3 0.7 4.5 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ArsR PF09824.9 PXF45989.1 - 0.1 12.2 0.7 1.3 8.6 0.1 2.7 2 0 0 2 2 2 0 ArsR transcriptional regulator FCH PF00611.23 PXF45989.1 - 0.37 11.1 11.3 0.11 12.8 1.7 4.3 4 1 0 4 4 4 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2316 PF10078.9 PXF45989.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF1326 PF07040.11 PXF45989.1 - 1 9.3 8.2 0.83 9.6 5.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1326) FYVE_2 PF02318.16 PXF45990.1 - 1.2 9.4 4.8 22 5.3 0.2 2.9 2 0 0 2 2 2 0 FYVE-type zinc finger TMF_TATA_bd PF12325.8 PXF45990.1 - 1.4 9.2 19.4 0.49 10.6 7.0 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CCDC144C PF14915.6 PXF45990.1 - 1.5 7.8 23.4 0.011 14.8 2.3 3.3 2 1 1 3 3 3 0 CCDC144C protein coiled-coil region DUF1664 PF07889.12 PXF45990.1 - 4.6 7.3 18.5 0.054 13.5 1.8 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 PXF45990.1 - 9.2 6.3 9.0 21 5.1 0.6 3.4 2 1 0 3 3 3 0 Sec20 Ank_2 PF12796.7 PXF45992.1 - 3.1e-112 367.4 82.8 3e-14 53.4 2.8 11.1 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF45992.1 - 3e-70 231.7 44.4 9.2e-07 29.3 0.0 17.3 4 3 15 19 19 19 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF45992.1 - 6.4e-69 219.7 19.6 0.00084 19.6 0.0 20.3 21 0 0 21 21 21 15 Ankyrin repeat Ank PF00023.30 PXF45992.1 - 7.3e-61 200.1 70.6 0.0005 20.4 0.1 20.4 20 0 0 20 20 20 18 Ankyrin repeat Ank_5 PF13857.6 PXF45992.1 - 1.8e-60 200.2 60.4 8.1e-09 35.6 0.3 16.3 4 4 13 17 17 17 17 Ankyrin repeats (many copies) CCDC-167 PF15188.6 PXF45992.1 - 0.056 13.8 1.5 0.23 11.8 1.5 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HMMR_N PF15905.5 PXF45992.1 - 0.23 10.9 9.7 0.55 9.6 4.1 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TACC_C PF05010.14 PXF45992.1 - 0.76 9.5 8.7 0.036 13.9 2.8 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-C4H2 PF10146.9 PXF45992.1 - 1.4 9.2 8.6 0.54 10.5 1.4 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein RecX PF02631.16 PXF45992.1 - 1.4 9.4 4.8 6.3 7.3 1.7 3.7 5 0 0 5 5 4 0 RecX family Mod_r PF07200.13 PXF45992.1 - 6.8 6.8 11.0 4.2 7.5 2.5 3.9 5 0 0 5 5 5 0 Modifier of rudimentary (Mod(r)) protein eIF-1a PF01176.19 PXF45993.1 - 2.5e-09 36.8 0.1 4.1e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DEAD PF00270.29 PXF45994.1 - 3.1e-16 59.7 0.0 8.2e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase TRCF PF03461.15 PXF45994.1 - 5.1e-16 58.8 0.0 1.1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 TRCF domain Helicase_C PF00271.31 PXF45994.1 - 1.7e-15 57.3 0.2 3.4e-14 53.1 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CarD_CdnL_TRCF PF02559.16 PXF45994.1 - 2.1e-12 47.6 0.0 1.9e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 CarD-like/TRCF domain ResIII PF04851.15 PXF45994.1 - 9.2e-09 35.5 0.0 4.8e-08 33.2 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 PXF45994.1 - 0.0014 18.6 0.1 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SQHop_cyclase_C PF13243.6 PXF45995.1 - 1.6e-51 175.4 5.8 8.9e-46 156.4 2.6 3.0 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 PXF45995.1 - 4e-45 154.2 0.1 5.6e-36 124.1 0.0 5.2 4 1 1 5 5 5 5 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 PXF45995.1 - 8.7e-28 95.8 18.9 4.8e-09 35.8 1.1 6.8 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 PXF45995.1 - 6.7e-06 25.4 3.3 0.06 12.4 0.9 4.2 2 1 2 4 4 4 3 A-macroglobulin TED domain Pec_lyase PF09492.10 PXF45995.1 - 0.0026 17.1 0.6 6.3 6.0 0.1 4.0 4 1 0 4 4 4 1 Pectic acid lyase ABC_membrane_2 PF06472.15 PXF45997.1 - 1e-66 225.1 0.3 1.3e-66 224.8 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF45997.1 - 6.2e-19 68.9 0.0 1.5e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF45997.1 - 0.00043 20.2 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PXF45997.1 - 0.00079 19.8 1.0 0.0037 17.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 PXF45997.1 - 0.0017 17.9 0.1 0.047 13.1 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PXF45997.1 - 0.0074 16.0 0.1 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF45997.1 - 0.023 15.2 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF45997.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF45997.1 - 0.11 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 PXF45997.1 - 0.11 12.0 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 PXF45997.1 - 0.14 11.9 0.0 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 PXF45997.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 PXF45997.1 - 0.16 12.0 0.0 0.54 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Phage_GPO PF05929.11 PXF45997.1 - 0.19 11.4 0.0 0.5 9.9 0.0 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Chorein_N PF12624.7 PXF45998.1 - 5.2e-17 62.0 0.0 1.6e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 PXF45998.1 - 0.00011 22.1 0.6 0.00037 20.4 0.6 1.9 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal DnaJ_C PF01556.18 PXF45999.1 - 8.8e-32 110.2 0.1 1.2e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF45999.1 - 1e-25 89.6 2.7 1.8e-25 88.8 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PXF45999.1 - 2.6e-08 34.1 12.1 4.8e-08 33.3 12.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Zn-ribbon_8 PF09723.10 PXF45999.1 - 0.078 13.1 3.0 0.11 12.6 0.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain MCM_OB PF17207.3 PXF45999.1 - 0.17 11.7 2.4 0.25 11.2 0.9 1.9 2 0 0 2 2 2 0 MCM OB domain Lar_restr_allev PF14354.6 PXF45999.1 - 0.61 10.5 5.1 9.7 6.7 5.1 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.7 PXF45999.1 - 1.5 8.9 7.6 2.5 8.2 7.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Anti-TRAP PF15777.5 PXF45999.1 - 8.7 6.4 10.3 15 5.6 3.6 2.5 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Carb_anhydrase PF00194.21 PXF46000.1 - 1.3e-22 80.6 0.3 8.6e-15 55.0 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Aldose_epim PF01263.20 PXF46002.1 - 7.6e-48 163.3 0.0 9.3e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AAA PF00004.29 PXF46003.1 - 1.4e-17 64.3 0.0 3.8e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CCDC117 PF15810.5 PXF46003.1 - 0.0027 18.0 0.4 0.0061 16.9 0.4 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 117 AAA_16 PF13191.6 PXF46003.1 - 0.0073 16.7 0.1 0.026 14.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 PXF46003.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma70_ner PF04546.13 PXF46003.1 - 0.014 15.3 2.7 0.014 15.3 2.7 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 PXF46003.1 - 0.018 13.4 10.3 0.025 12.9 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 PXF46003.1 - 0.04 14.4 0.0 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 PXF46003.1 - 0.07 12.7 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain eIF-3c_N PF05470.12 PXF46003.1 - 0.076 11.3 2.7 0.12 10.7 2.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA_22 PF13401.6 PXF46003.1 - 0.11 12.8 0.2 0.75 10.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 PXF46003.1 - 0.12 11.6 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 KaiC RRN3 PF05327.11 PXF46003.1 - 0.33 9.5 6.4 0.53 8.8 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_11 PF13086.6 PXF46003.1 - 0.56 10.0 0.0 0.56 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain DNA_pol_phi PF04931.13 PXF46003.1 - 0.94 7.5 16.4 2.1 6.3 16.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 PXF46003.1 - 2.3 7.5 10.9 4.2 6.6 10.9 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 PXF46003.1 - 7.2 6.6 8.7 0.49 10.4 2.3 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal RNA_pol_Rpc4 PF05132.14 PXF46003.1 - 9.7 6.6 7.6 22 5.4 1.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2853 PF11015.8 PXF46004.1 - 0.087 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) DUF3110 PF11360.8 PXF46005.1 - 0.16 12.2 1.0 18 5.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) CAAD PF14159.6 PXF46006.1 - 2.2e-23 81.9 0.2 3.1e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DEAD PF00270.29 PXF46008.1 - 4.9e-41 140.4 0.0 6.6e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF46008.1 - 2e-29 102.2 0.2 1.4e-28 99.4 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF46008.1 - 2e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PXF46008.1 - 0.0047 16.2 0.1 0.0071 15.6 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Sirohm_synth_M PF14824.6 PXF46008.1 - 0.0055 16.1 0.5 0.012 15.0 0.5 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central HEAT_2 PF13646.6 PXF46009.1 - 7.2e-09 35.9 11.6 6.8e-07 29.6 5.5 3.1 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 PXF46009.1 - 9.3e-09 35.6 9.5 1.4e-06 28.7 4.8 3.5 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 PXF46009.1 - 2e-08 33.8 11.9 0.03 14.6 0.3 4.0 4 0 0 4 4 4 3 HEAT repeat Fes1 PF08609.10 PXF46009.1 - 4e-07 30.8 0.1 9.9e-06 26.4 0.0 2.8 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 PXF46009.1 - 6.2e-06 25.6 0.1 9e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Arm PF00514.23 PXF46009.1 - 1.9e-05 24.5 0.6 0.11 12.6 0.3 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 PXF46009.1 - 4.7e-05 23.5 0.1 8.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 PXF46009.1 - 0.003 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 PXF46009.1 - 0.019 15.6 8.0 0.52 11.1 0.3 4.1 3 1 0 3 3 3 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 PXF46009.1 - 0.17 11.9 0.2 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain VEFS-Box PF09733.9 PXF46010.1 - 1.3e-14 54.2 0.1 3.6e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 VEFS-Box of polycomb protein LAL_C2 PF18603.1 PXF46010.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 ANAPC4_WD40 PF12894.7 PXF46011.1 - 1.4e-08 34.9 0.1 0.62 10.4 0.0 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF46011.1 - 1.6e-07 31.9 4.9 0.11 13.4 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 PXF46011.1 - 0.00022 20.7 0.1 0.86 8.9 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 PXF46011.1 - 0.00036 20.2 0.1 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.6 PXF46011.1 - 0.0031 17.5 0.0 0.11 12.5 0.0 2.5 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 PXF46011.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 PXF46011.1 - 0.051 14.1 0.3 62 4.3 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain SNF5 PF04855.12 PXF46012.1 - 2.7e-44 151.7 5.6 1.4e-26 93.8 1.2 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 CCDC23 PF15674.5 PXF46012.1 - 0.28 11.2 4.1 0.66 10.0 4.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 WTX PF09422.10 PXF46013.1 - 3.6 6.6 11.8 0.035 13.2 3.8 1.6 2 0 0 2 2 2 0 WTX protein Tantalus PF15386.6 PXF46016.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Drosophila Tantalus-like Hydrolase_like PF13242.6 PXF46017.1 - 2.7e-12 46.6 0.2 6.2e-12 45.4 0.2 1.5 1 1 1 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 PXF46017.1 - 5.1e-05 23.4 0.0 6.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF46017.1 - 0.0035 17.7 0.4 0.0087 16.4 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PXF46018.1 - 4.8e-14 52.8 0.0 6.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF46018.1 - 8.8e-13 48.1 0.2 2e-12 47.0 0.2 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 PXF46018.1 - 3.2e-09 37.4 0.5 1.3e-08 35.4 0.2 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF46018.1 - 1.6e-07 31.9 0.3 6.9e-07 29.9 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PXF46018.1 - 0.035 13.8 0.0 5.6 6.6 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 PXF46018.1 - 0.088 12.4 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) YchF-GTPase_C PF06071.13 PXF46019.1 - 6.5e-40 135.2 0.1 1.5e-39 134.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PXF46019.1 - 2.7e-23 82.2 0.0 9.9e-23 80.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF46019.1 - 1.3e-07 31.3 0.1 5.3e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PXF46019.1 - 0.042 13.9 0.0 6.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 PXF46019.1 - 0.1 12.5 0.1 0.78 9.6 0.0 2.4 2 1 1 3 3 3 0 RsgA GTPase Roc PF08477.13 PXF46019.1 - 0.15 12.3 0.0 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DpnII PF04556.12 PXF46020.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 DpnII restriction endonuclease SNase PF00565.17 PXF46022.1 - 1e-08 35.6 0.0 1.9e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue LTD PF00932.19 PXF46023.1 - 6.4e-07 29.7 0.1 1.3e-06 28.7 0.1 1.5 1 1 0 1 1 1 1 Lamin Tail Domain Elf1 PF05129.13 PXF46024.1 - 0.051 13.6 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ADH_N PF08240.12 PXF46026.1 - 1.1e-23 83.2 0.7 2.2e-23 82.2 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF46026.1 - 9.1e-14 51.6 0.1 2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PXF46026.1 - 0.00013 23.0 0.0 0.00029 21.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PXF46026.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 PXF46026.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_integrase PF00589.22 PXF46029.1 - 0.038 13.8 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family MutL_C PF08676.11 PXF46030.1 - 9.6e-17 61.1 0.0 2.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Zn_Tnp_IS91 PF14319.6 PXF46030.1 - 1.3 9.1 6.7 7.1 6.7 3.7 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.12 PXF46030.1 - 1.8 8.6 6.9 1.1 9.3 3.7 2.3 2 0 0 2 2 2 0 zinc-ribbons HA2 PF04408.23 PXF46031.1 - 7.1e-19 68.1 0.2 1.8e-18 66.8 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PXF46031.1 - 1.8e-14 53.8 0.0 4.1e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PXF46031.1 - 2.9e-09 37.3 0.0 8.8e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF46031.1 - 6.9e-05 22.7 0.2 0.00014 21.7 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PXF46031.1 - 0.0049 17.2 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF46031.1 - 0.053 12.6 0.2 0.37 9.8 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Trypsin PF00089.26 PXF46032.1 - 1.3e-27 97.1 0.0 1.6e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF46032.1 - 5.8e-10 40.3 0.0 1.3e-09 39.1 0.0 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain His_Phos_1 PF00300.22 PXF46033.1 - 1.4e-29 103.2 0.0 1.7e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ANAPC4_WD40 PF12894.7 PXF46034.1 - 0.0011 19.2 0.1 0.03 14.6 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L28 PF00830.19 PXF46034.1 - 3.4 7.9 6.8 0.73 10.1 2.7 2.0 2 0 0 2 2 2 0 Ribosomal L28 family DDE_1 PF03184.19 PXF46035.1 - 2.5e-13 50.0 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 PXF46035.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease CTU2 PF10288.9 PXF46036.1 - 2.3e-05 24.6 6.9 0.00016 21.9 6.9 2.3 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 MAPEG PF01124.18 PXF46037.1 - 1.1e-10 41.4 1.5 1.4e-10 41.2 1.5 1.1 1 0 0 1 1 1 1 MAPEG family Uma2 PF05685.12 PXF46038.1 - 3.4e-26 91.8 0.0 4.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease DUF3591 PF12157.8 PXF46039.1 - 2.2e-42 145.2 0.6 1e-41 143.0 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 PXF46039.1 - 5.1e-14 52.1 0.1 2.3e-13 50.0 0.1 2.1 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 PXF46039.1 - 4.7e-09 36.4 0.4 4.7e-09 36.4 0.4 2.1 2 0 0 2 2 2 1 TATA box-binding protein binding RskA PF10099.9 PXF46040.1 - 0.038 14.3 2.9 0.057 13.7 2.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MMS19_C PF12460.8 PXF46041.1 - 0.021 13.9 1.9 0.029 13.5 1.9 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal FOXP-CC PF16159.5 PXF46041.1 - 0.055 14.1 0.1 0.3 11.7 0.1 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain Prominin PF05478.11 PXF46041.1 - 0.13 10.2 1.7 0.19 9.6 1.7 1.2 1 0 0 1 1 1 0 Prominin eIF3_p135 PF12807.7 PXF46041.1 - 0.22 11.6 1.0 0.61 10.1 1.0 1.8 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Codanin-1_C PF15296.6 PXF46041.1 - 0.22 11.6 5.3 0.98 9.5 5.3 2.1 1 1 0 1 1 1 0 Codanin-1 C-terminus SlyX PF04102.12 PXF46041.1 - 0.41 11.3 3.0 6.5 7.5 0.0 3.4 2 1 1 3 3 3 0 SlyX Strep_SA_rep PF06696.11 PXF46041.1 - 0.57 10.2 2.1 0.54 10.3 0.2 2.0 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Pex19 PF04614.12 PXF46041.1 - 1.4 8.6 9.9 1.9 8.2 8.7 1.9 2 1 0 2 2 2 0 Pex19 protein family Peptidase_M14 PF00246.24 PXF46042.1 - 2.4e-08 34.1 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TPR_19 PF14559.6 PXF46043.1 - 7.4e-33 112.9 12.5 1.7e-09 38.0 2.0 6.0 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46043.1 - 2.8e-26 89.5 15.4 0.022 14.9 0.1 11.3 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46043.1 - 6.9e-24 82.5 47.3 5.9e-05 23.5 1.8 10.6 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46043.1 - 4.3e-18 64.0 0.0 0.047 13.9 0.0 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF46043.1 - 4.7e-17 62.0 25.4 0.00031 21.0 0.3 7.1 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46043.1 - 1.2e-16 59.8 0.4 0.77 9.7 0.0 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF46043.1 - 8.9e-16 58.3 36.6 0.00038 21.1 8.1 7.0 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 PXF46043.1 - 3e-15 55.4 3.1 0.53 10.8 0.0 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 PXF46043.1 - 2.4e-09 37.2 16.5 0.15 12.7 0.1 9.7 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46043.1 - 1.4e-08 34.2 10.2 22 5.4 0.0 9.4 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_9 PF13371.6 PXF46043.1 - 2.4e-07 30.8 30.5 0.053 13.7 4.2 6.7 1 1 6 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46043.1 - 2e-06 27.3 0.8 2.9 7.7 0.0 7.4 6 3 3 9 9 9 1 TPR repeat ANAPC3 PF12895.7 PXF46043.1 - 2e-05 24.7 6.8 0.0015 18.7 0.0 4.9 4 2 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 PXF46043.1 - 0.0042 17.1 1.2 2.8 7.8 0.3 3.0 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_4 PF07721.14 PXF46043.1 - 0.011 16.2 2.2 0.011 16.2 2.2 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat NARP1 PF12569.8 PXF46043.1 - 0.018 13.9 1.3 1.2 8.0 0.3 2.6 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 PXF46043.1 - 0.024 14.6 0.0 10 6.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PXF46043.1 - 0.099 12.3 0.1 0.099 12.3 0.1 3.7 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Mad3_BUB1_I PF08311.12 PXF46043.1 - 0.23 11.4 9.4 20 5.2 1.0 4.9 3 1 1 4 4 4 0 Mad3/BUB1 homology region 1 Proteasome PF00227.26 PXF46045.1 - 5.1e-34 117.4 0.2 6.2e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit ADH_N PF08240.12 PXF46046.1 - 2.8e-23 81.9 1.0 4.8e-23 81.1 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF46046.1 - 1.2e-17 64.1 0.0 2.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PXF46046.1 - 0.00041 21.4 0.0 0.0011 20.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PXF46046.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 PXF46046.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PXF46046.1 - 0.041 13.2 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_6 PF12837.7 PXF46046.1 - 0.042 13.9 1.1 0.1 12.7 1.1 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain AAA PF00004.29 PXF46047.1 - 9.7e-41 139.3 0.0 2e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF46047.1 - 2.7e-09 36.7 0.1 7.5e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PXF46047.1 - 5.8e-06 26.4 0.2 2.5e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PXF46047.1 - 1.4e-05 25.3 0.0 3.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PXF46047.1 - 1.8e-05 25.0 0.1 0.00016 21.9 0.0 2.4 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 PXF46047.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 PXF46047.1 - 0.0017 17.8 0.1 2.2 7.7 0.0 2.8 2 1 1 3 3 3 2 Bacterial TniB protein TIP49 PF06068.13 PXF46047.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Vps4_C PF09336.10 PXF46047.1 - 0.003 17.5 0.1 0.0099 15.9 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 PXF46047.1 - 0.0047 17.3 1.0 0.023 15.1 0.4 2.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 PXF46047.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PXF46047.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PXF46047.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PXF46047.1 - 0.083 12.5 0.5 4.6 6.8 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 PXF46047.1 - 0.089 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PXF46047.1 - 0.12 12.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 PXF46047.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MOSC PF03473.17 PXF46048.1 - 1.8e-06 28.0 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Myb_DNA-bind_4 PF13837.6 PXF46049.1 - 0.53 10.7 2.7 1.6 9.1 0.5 2.6 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain SET PF00856.28 PXF46051.1 - 5.8e-08 33.3 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PXF46051.1 - 0.00016 22.3 0.1 0.00042 21.0 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding ELP6 PF09807.9 PXF46051.1 - 0.08 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Elongation complex protein 6 PAP_fibrillin PF04755.12 PXF46052.1 - 3.4e-29 102.2 0.3 7.7e-29 101.1 0.3 1.6 1 1 0 1 1 1 1 PAP_fibrillin HAD_2 PF13419.6 PXF46053.1 - 1.8e-27 96.6 0.0 3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF46053.1 - 2.2e-14 54.2 2.0 6.5e-14 52.7 2.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-met PF12874.7 PXF46053.1 - 3.9e-12 46.1 25.4 5.7e-07 29.7 2.0 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Hydrolase_like PF13242.6 PXF46053.1 - 1.1e-07 31.9 0.4 2.4e-07 30.7 0.4 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C2H2_jaz PF12171.8 PXF46053.1 - 8e-07 29.2 20.1 0.0017 18.6 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF46053.1 - 3.5e-05 24.1 16.7 0.16 12.3 1.5 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PXF46053.1 - 0.0086 16.5 7.8 0.08 13.4 1.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type AKAP95 PF04988.12 PXF46053.1 - 0.011 15.9 12.2 0.17 12.1 4.8 3.6 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 PXF46053.1 - 0.023 15.5 6.2 1.2 10.2 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PXF46053.1 - 0.74 9.9 4.8 0.81 9.8 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MRP-L20 PF12824.7 PXF46054.1 - 8.5e-06 26.0 3.2 1.1e-05 25.6 3.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Bot1p PF12298.8 PXF46054.1 - 0.0018 18.4 1.7 0.0031 17.7 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein UPF0240 PF06784.11 PXF46054.1 - 0.046 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF1978 PF09321.10 PXF46054.1 - 0.077 12.3 2.5 0.11 11.8 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) DNA_topoisoIV PF00521.20 PXF46054.1 - 0.23 10.3 1.1 0.31 9.9 1.1 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Lactamase_B_2 PF12706.7 PXF46055.1 - 1.4e-08 34.5 0.3 0.00022 20.8 0.0 2.8 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF46055.1 - 0.00018 21.6 0.1 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Latrophilin PF02354.16 PXF46055.1 - 5.8 5.9 6.6 1.8 7.5 2.7 2.0 2 0 0 2 2 2 0 Latrophilin Cytoplasmic C-terminal region Asp_protease_2 PF13650.6 PXF46057.1 - 0.0057 17.3 0.1 0.12 13.0 0.0 2.3 1 1 1 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PXF46057.1 - 0.031 14.9 0.0 0.23 12.0 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease AdoHcyase_NAD PF00670.21 PXF46060.1 - 2.7e-44 151.1 0.2 3.4e-44 150.8 0.2 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 PXF46060.1 - 2.7e-06 26.8 0.0 3.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 PXF46060.1 - 0.0041 16.5 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF5511 PF17630.2 PXF46061.1 - 0.081 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5511) Amino_oxidase PF01593.24 PXF46062.1 - 6.8e-13 48.7 0.0 1.4e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF46062.1 - 6.5e-11 42.3 0.1 4.8e-10 39.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF46062.1 - 6.8e-06 25.9 1.0 0.003 17.2 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF46062.1 - 0.0018 18.3 1.0 0.014 15.4 0.1 2.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 PXF46062.1 - 0.025 13.3 0.1 3.1 6.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 PXF46062.1 - 0.079 11.7 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 MCRA family Pyr_redox_2 PF07992.14 PXF46062.1 - 0.15 11.3 0.8 2.7 7.1 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Retrotran_gag_2 PF14223.6 PXF46064.1 - 9.7e-09 35.0 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PXF46064.1 - 0.0014 18.3 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PXF46064.1 - 0.0043 16.8 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Mtd_N PF18454.1 PXF46065.1 - 0.065 13.3 0.2 0.18 11.9 0.2 1.8 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain RVT_2 PF07727.14 PXF46066.1 - 5.3e-07 29.5 0.2 6e-07 29.4 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.8 PXF46066.1 - 0.049 13.2 0.4 0.08 12.5 0.2 1.4 1 1 0 1 1 1 0 Ty3 transposon peptidase AIG1 PF04548.16 PXF46067.1 - 4.1e-10 39.4 0.0 8.8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PXF46067.1 - 2.1e-09 37.4 0.0 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF46067.1 - 2.5e-05 24.3 0.1 6.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 PXF46067.1 - 0.00081 19.5 2.5 0.28 11.2 0.1 3.2 2 2 2 4 4 4 2 Dynamin family ABC_tran PF00005.27 PXF46067.1 - 0.0021 18.6 1.1 0.006 17.1 0.0 2.3 2 1 0 2 2 2 1 ABC transporter Roc PF08477.13 PXF46067.1 - 0.023 14.9 0.0 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 PXF46067.1 - 0.025 14.1 0.0 0.064 12.8 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 PXF46067.1 - 0.076 13.4 0.1 0.32 11.4 0.1 2.1 1 0 0 1 1 1 0 RNA helicase AIG1 PF04548.16 PXF46068.1 - 1.6e-12 47.2 0.0 3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PXF46068.1 - 3.1e-11 43.3 0.0 1.1e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF46068.1 - 1.2e-05 25.3 0.6 3.4e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 PXF46068.1 - 0.00013 22.1 0.1 0.00045 20.4 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PXF46068.1 - 0.00062 19.2 0.0 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 PXF46068.1 - 0.0013 19.2 0.7 0.0055 17.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Ras PF00071.22 PXF46068.1 - 0.0015 18.1 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 PXF46068.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 PXF46068.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 PXF46068.1 - 0.44 10.6 4.8 0.59 10.2 0.2 3.0 2 1 1 3 3 3 0 Dynamin family Hint PF01079.20 PXF46070.1 - 2.6e-12 46.7 0.1 5.1e-06 26.1 0.1 2.2 1 1 1 2 2 2 2 Hint module RTC_insert PF05189.13 PXF46070.1 - 0.042 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain MmgE_PrpD PF03972.14 PXF46071.1 - 5.1e-27 94.5 0.0 6.3e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MmgE_PrpD PF03972.14 PXF46072.1 - 8.1e-24 83.9 0.9 9.7e-24 83.7 0.9 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1424 PF07232.11 PXF46073.1 - 0.058 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) Ta0938 PF11494.8 PXF46074.1 - 0.074 13.3 0.1 3.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Ta0938 Sel1 PF08238.12 PXF46077.1 - 6.5e-22 77.5 7.6 1.8e-06 28.4 0.0 8.0 7 0 0 7 7 7 4 Sel1 repeat TPR_14 PF13428.6 PXF46077.1 - 0.066 14.1 32.3 20 6.4 0.1 9.5 6 2 3 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46077.1 - 1.2 9.3 12.9 27 5.1 0.8 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF4392 PF14336.6 PXF46078.1 - 0.19 11.1 0.2 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF755 PF05501.11 PXF46079.1 - 0.00033 20.9 3.4 0.00079 19.7 3.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Snapin_Pallidin PF14712.6 PXF46079.1 - 0.0094 16.3 1.2 0.045 14.2 1.2 2.0 1 1 0 1 1 1 1 Snapin/Pallidin SR-25 PF10500.9 PXF46079.1 - 0.027 14.1 11.3 0.042 13.5 11.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPV_P10 PF05531.12 PXF46079.1 - 0.23 11.9 2.6 0.33 11.4 0.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF996 PF06195.13 PXF46080.1 - 0.0047 17.2 0.2 0.0072 16.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF996) TMEM192 PF14802.6 PXF46080.1 - 0.041 13.0 0.1 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 TMEM192 family DUF1129 PF06570.11 PXF46080.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF1218 PF06749.12 PXF46080.1 - 0.19 12.3 4.0 0.23 12.0 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Med10 PF09748.9 PXF46082.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Pet127 PF08634.10 PXF46083.1 - 0.07 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet127 UPF0054 PF02130.17 PXF46084.1 - 2.2e-24 85.7 0.1 2.8e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Rtf2 PF04641.12 PXF46085.1 - 2.2e-27 96.0 1.1 9.4e-27 94.0 1.1 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger DDE_Tnp_1_7 PF13843.6 PXF46087.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase IS4 C1_1 PF00130.22 PXF46087.1 - 0.21 11.5 3.9 0.45 10.4 3.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FAD_binding_3 PF01494.19 PXF46088.1 - 5.4e-18 65.4 0.0 1.8e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PXF46088.1 - 6e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PXF46088.1 - 0.00013 21.4 0.0 0.00031 20.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF46088.1 - 0.00079 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PXF46088.1 - 0.0058 15.4 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 PXF46088.1 - 0.016 14.5 0.0 0.055 12.7 0.0 1.6 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF46088.1 - 0.076 12.6 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 PXF46088.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 PXF46088.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Epimerase PF01370.21 PXF46091.1 - 0.001 18.6 0.5 0.49 9.8 0.0 3.0 2 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 PXF46091.1 - 0.042 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 PXF46091.1 - 0.084 13.1 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.6 PXF46091.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding FAD_binding_3 PF01494.19 PXF46092.1 - 1.3e-09 37.8 0.0 1.1e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 PXF46092.1 - 0.02 14.0 0.0 0.044 12.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase CAP PF00188.26 PXF46095.1 - 2.5e-07 31.6 1.1 4.4e-07 30.8 1.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DEC-1_N PF04625.13 PXF46095.1 - 1 8.3 7.1 1.3 7.9 7.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Sulfotransfer_2 PF03567.14 PXF46097.1 - 9.4e-07 29.0 0.1 9.4e-07 29.0 0.1 2.4 2 1 0 2 2 2 1 Sulfotransferase family Raftlin PF15250.6 PXF46097.1 - 1 8.1 10.1 1.8 7.2 10.1 1.3 1 0 0 1 1 1 0 Raftlin BSP_II PF05432.11 PXF46097.1 - 2 8.0 15.6 3.4 7.3 15.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PTS-HPr PF00381.19 PXF46098.1 - 0.021 15.0 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 PTS HPr component phosphorylation site Thioredoxin_4 PF13462.6 PXF46098.1 - 0.11 12.6 1.0 0.22 11.7 1.0 1.5 1 0 0 1 1 1 0 Thioredoxin Cyclin_N PF00134.23 PXF46099.1 - 2.9e-47 159.6 1.1 1.8e-45 153.8 0.5 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF46099.1 - 5.9e-17 61.9 0.0 5.9e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Hint PF01079.20 PXF46100.1 - 1e-13 51.3 0.1 6.2e-13 48.8 0.1 1.9 1 1 0 1 1 1 1 Hint module DUF1995 PF09353.10 PXF46101.1 - 2.6e-25 89.6 0.0 2.9e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Mito_carr PF00153.27 PXF46102.1 - 2.8e-28 97.7 4.0 1.1e-15 57.3 0.2 5.1 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PXF46102.1 - 0.24 10.5 2.6 1.9 7.6 0.3 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Trp_oprn_chp PF09534.10 PXF46102.1 - 0.43 10.4 7.2 0.084 12.7 3.4 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Zip PF02535.22 PXF46103.1 - 3.1e-35 122.0 23.7 6.5e-33 114.4 7.9 3.7 2 1 1 3 3 3 3 ZIP Zinc transporter DUF563 PF04577.14 PXF46107.1 - 3.8e-17 63.1 0.0 5.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_C48 PF02902.19 PXF46111.1 - 5.1e-27 95.1 0.3 3.2e-25 89.2 0.0 2.7 2 1 1 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain Exo_endo_phos PF03372.23 PXF46112.1 - 5.7e-09 35.8 0.0 4.7e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SATase_N PF06426.14 PXF46113.1 - 8.7e-39 132.1 1.4 1.6e-38 131.3 1.4 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 PXF46113.1 - 2.2e-11 43.0 5.0 9.8e-07 28.3 0.0 2.9 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PXF46113.1 - 0.24 11.2 11.5 0.19 11.5 1.1 2.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Rer1 PF03248.13 PXF46114.1 - 1.7e-61 206.9 9.8 2.2e-61 206.5 9.8 1.1 1 0 0 1 1 1 1 Rer1 family UCH PF00443.29 PXF46115.1 - 2.4e-22 79.7 0.0 8.9e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF46115.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.5 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Gln-synt_C PF00120.24 PXF46116.1 - 1.8e-19 70.0 0.0 2.8e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PXF46116.1 - 6.7e-11 41.8 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 PXF46117.1 - 1.3e-16 60.6 0.0 5.3e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PXF46117.1 - 9.7e-11 41.2 0.0 2.2e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain BACK PF07707.15 PXF46118.1 - 5.2e-10 39.3 0.3 1.2e-09 38.1 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch DUF3240 PF11582.8 PXF46118.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Pan3_PK PF18101.1 PXF46119.1 - 3.6e-47 159.8 0.0 5e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 PXF46119.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Inositol_P PF00459.25 PXF46120.1 - 5.4e-44 150.7 0.0 7.1e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 PXF46120.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain OTU PF02338.19 PXF46122.1 - 0.0024 18.3 0.0 0.0037 17.8 0.0 1.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PXF46122.1 - 0.094 12.2 0.0 0.55 9.6 0.0 2.0 2 1 0 2 2 2 0 Peptidase C65 Otubain Peptidase_C33 PF05412.12 PXF46122.1 - 0.14 12.2 0.1 0.83 9.7 0.1 1.9 1 1 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase DNA_pol_B PF00136.21 PXF46123.1 - 7.8e-119 397.4 0.7 1.8e-118 396.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 PXF46123.1 - 3.3e-23 82.4 0.0 6.6e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 PXF46123.1 - 3.4e-21 75.7 0.0 3.2e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 PXF46123.1 - 3e-08 33.6 2.4 3e-08 33.6 2.4 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 PXF46123.1 - 0.03 13.2 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DJ-1_PfpI PF01965.24 PXF46124.1 - 4.6e-39 133.9 0.7 5.4e-39 133.6 0.7 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 PXF46124.1 - 0.026 14.1 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Sel1 PF08238.12 PXF46125.1 - 9.4e-81 264.4 15.6 6.4e-07 29.8 0.1 14.5 15 0 0 15 15 15 14 Sel1 repeat TPR_6 PF13174.6 PXF46125.1 - 2.7e-11 43.4 18.0 6.8 7.6 0.1 12.7 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46125.1 - 1.2e-07 31.2 26.0 2.5 8.3 0.4 12.2 11 3 1 12 12 12 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF46125.1 - 1.2e-05 25.4 9.2 16 6.2 0.0 10.2 10 3 1 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF46125.1 - 1.3e-05 25.7 31.0 4.8 7.9 0.7 9.7 8 3 3 11 11 11 2 Tetratricopeptide repeat TPR_5 PF12688.7 PXF46125.1 - 0.00013 22.2 13.6 4.2 7.7 0.0 8.7 7 3 4 11 11 11 2 Tetratrico peptide repeat TPR_1 PF00515.28 PXF46125.1 - 0.0014 18.3 11.0 19 5.3 0.0 8.6 10 0 0 10 10 10 0 Tetratricopeptide repeat YqaH PF17448.2 PXF46125.1 - 0.0015 18.8 1.2 4.4 7.7 0.0 5.4 6 1 0 6 6 6 1 Uncharacterized YqaH-like TPR_14 PF13428.6 PXF46125.1 - 0.002 18.8 32.7 5.8 8.0 0.0 11.3 6 4 6 12 12 12 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46125.1 - 0.022 14.4 4.9 2.5 7.8 0.0 5.5 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 PXF46125.1 - 0.082 13.1 22.5 52 4.3 0.0 10.6 11 1 1 12 12 12 0 Tetratricopeptide repeat NSF PF02071.20 PXF46125.1 - 1.1 10.3 19.1 30 6.0 1.1 8.7 9 0 0 9 9 9 0 Aromatic-di-Alanine (AdAR) repeat TPR_12 PF13424.6 PXF46125.1 - 2 8.7 23.8 1.4 9.2 0.3 8.2 7 3 2 9 9 9 0 Tetratricopeptide repeat RINT1_TIP1 PF04437.13 PXF46126.1 - 2.9e-16 59.5 0.2 4.6e-14 52.2 0.1 3.5 2 1 0 2 2 2 1 RINT-1 / TIP-1 family PliI PF16743.5 PXF46126.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Periplasmic lysozyme inhibitor of I-type lysozyme MreB_Mbl PF06723.13 PXF46126.1 - 0.18 10.6 0.1 0.31 9.8 0.1 1.3 1 0 0 1 1 1 0 MreB/Mbl protein BssS PF13991.6 PXF46126.1 - 0.52 10.4 2.8 1.6 8.9 0.0 3.0 4 0 0 4 4 4 0 BssS protein family STAT_int PF02865.17 PXF46126.1 - 7.4 7.1 7.2 5.9 7.4 0.1 3.8 2 2 1 3 3 3 0 STAT protein, protein interaction domain NT-C2 PF10358.9 PXF46127.1 - 1.2e-09 38.1 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Cob_adeno_trans PF01923.18 PXF46127.1 - 0.0059 16.8 2.8 0.018 15.2 2.8 1.9 1 0 0 1 1 1 1 Cobalamin adenosyltransferase bZIP_1 PF00170.21 PXF46127.1 - 0.017 15.2 4.0 0.017 15.2 4.0 3.4 3 1 1 4 4 4 0 bZIP transcription factor LPP PF04728.13 PXF46127.1 - 0.063 13.7 0.6 0.063 13.7 0.6 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper JIP_LZII PF16471.5 PXF46127.1 - 0.14 12.4 13.6 0.72 10.1 0.3 2.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF3450 PF11932.8 PXF46127.1 - 0.16 11.2 11.2 0.91 8.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WDCP PF15390.6 PXF46127.1 - 1.5 7.1 13.4 2.3 6.5 13.4 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SHE3 PF17078.5 PXF46127.1 - 2.2 7.9 17.2 47 3.6 1.1 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 PXF46127.1 - 2.9 5.7 7.9 4.4 5.1 7.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sedlin_N PF04628.13 PXF46128.1 - 1.6e-09 38.0 0.0 1.9e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NTP_transferase PF00483.23 PXF46129.1 - 2.9e-50 171.2 0.0 4.1e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 PXF46129.1 - 6.3e-16 57.4 24.3 4.4e-07 29.4 2.1 3.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 PXF46129.1 - 8e-11 42.6 0.0 1.3e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 PXF46129.1 - 7.4e-08 32.0 3.8 0.013 15.3 0.0 3.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 PXF46129.1 - 0.0025 16.1 0.2 0.0035 15.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PXF46129.1 - 0.0054 15.7 0.3 1.4 7.8 0.1 2.9 2 1 1 3 3 3 1 L-fucokinase IspD PF01128.19 PXF46129.1 - 0.059 13.1 0.1 0.24 11.1 0.0 2.0 3 0 0 3 3 3 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ldh_1_N PF00056.23 PXF46130.1 - 2.2e-32 112.1 0.0 3.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PXF46130.1 - 2.7e-28 99.0 0.1 5.8e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAD PF02109.16 PXF46131.1 - 9.9e-35 119.2 1.9 1.1e-34 119.0 1.9 1.0 1 0 0 1 1 1 1 DAD family YIF1 PF03878.15 PXF46131.1 - 0.0041 16.7 2.7 0.0048 16.4 2.7 1.0 1 0 0 1 1 1 1 YIF1 MNHE PF01899.16 PXF46131.1 - 0.027 14.2 1.4 0.05 13.4 1.3 1.5 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit Kelch_1 PF01344.25 PXF46132.1 - 2e-10 40.1 1.9 1.2e-06 28.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 PXF46132.1 - 7.8e-08 32.3 6.6 0.00029 21.0 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 PXF46132.1 - 8.9e-07 28.8 2.0 0.74 9.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PXF46132.1 - 2.4e-06 27.7 3.0 0.096 13.0 0.1 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 PXF46132.1 - 9.3e-05 22.4 1.8 0.056 13.5 0.0 3.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 PXF46132.1 - 0.003 17.5 4.9 13 6.0 0.0 4.7 5 0 0 5 5 5 1 Kelch motif DUF563 PF04577.14 PXF46133.1 - 1.2e-10 41.9 0.0 2.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) MMR_HSR1 PF01926.23 PXF46134.1 - 9.6e-18 64.3 0.0 1.3e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF46134.1 - 5.4e-09 35.8 0.0 3.1e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PXF46134.1 - 5.4e-05 23.2 0.0 0.012 15.5 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 PXF46134.1 - 0.00049 19.5 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 PXF46134.1 - 0.008 16.3 0.3 0.071 13.2 0.0 2.3 2 1 1 3 3 3 1 Dynamin family AAA_22 PF13401.6 PXF46134.1 - 0.094 13.0 0.0 0.44 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 PXF46134.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF46134.1 - 0.13 11.9 0.0 0.47 10.0 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 PXF46134.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain Arf PF00025.21 PXF46134.1 - 0.21 11.0 0.0 0.42 10.1 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Pro_isomerase PF00160.21 PXF46135.1 - 1.8e-41 142.1 0.0 2.8e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PXF46135.1 - 8.1e-06 25.4 0.2 3.8e-05 23.2 0.0 2.1 3 0 0 3 3 3 1 Rtf2 RING-finger Ribosomal_L16 PF00252.18 PXF46136.1 - 2.5e-43 147.2 0.0 3.2e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e dCMP_cyt_deam_1 PF00383.23 PXF46137.1 - 5.8e-16 58.2 0.1 7.1e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 PXF46137.1 - 5.5e-11 42.8 0.5 8.1e-09 35.8 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region NNMT_PNMT_TEMT PF01234.17 PXF46138.1 - 1.7e-34 119.2 0.0 2.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 PXF46138.1 - 0.0091 16.6 0.0 0.032 14.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 PXF46138.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_25 PF13649.6 PXF46138.1 - 0.019 15.7 0.0 0.076 13.7 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 PXF46138.1 - 0.027 15.2 0.0 0.057 14.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CutA1 PF03091.15 PXF46139.1 - 9.4e-34 115.2 0.0 1.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Pkinase PF00069.25 PXF46140.1 - 8e-62 209.0 0.0 1.7e-60 204.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46140.1 - 1.7e-29 102.9 0.0 2.3e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PXF46140.1 - 9.3e-07 29.0 3.7 7e-05 22.9 0.2 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF46140.1 - 9.2e-05 21.9 1.3 0.00014 21.3 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF46140.1 - 0.00069 18.5 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF46140.1 - 0.00082 18.8 0.0 0.0083 15.5 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 PXF46140.1 - 0.0015 19.1 0.1 0.0015 19.1 0.1 2.8 3 0 0 3 3 3 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 PXF46140.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 PXF46140.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FAM176 PF14851.6 PXF46140.1 - 1.3 8.7 3.3 2.9 7.6 3.3 1.5 1 0 0 1 1 1 0 FAM176 family Per1 PF04080.13 PXF46141.1 - 0.0066 16.3 0.1 0.0084 15.9 0.1 1.2 1 0 0 1 1 1 1 Per1-like family TPD PF14811.6 PXF46142.1 - 9.9e-43 145.3 0.0 1.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Profilin PF00235.19 PXF46143.1 - 8.3e-19 68.1 0.0 1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Profilin ATR13 PF16829.5 PXF46143.1 - 0.004 17.5 0.0 0.55 10.6 0.0 2.1 2 0 0 2 2 2 2 Avirulence protein ATR13, RxLR effector CpeT PF06206.11 PXF46144.1 - 2.7e-21 76.3 0.0 3.6e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) DDE_Tnp_4 PF13359.6 PXF46144.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 2 0 0 2 2 2 0 DDE superfamily endonuclease LRR_6 PF13516.6 PXF46145.1 - 0.006 16.5 11.3 1.8 8.8 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 PXF46145.1 - 0.012 16.0 0.3 7.2 7.2 0.1 4.0 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 PXF46145.1 - 0.17 12.2 0.5 8.5 6.7 0.0 3.1 3 0 0 3 3 3 0 Ste50p, sterile alpha motif F-box-like_2 PF13013.6 PXF46146.1 - 0.00012 22.0 0.5 0.00061 19.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like domain LRR_6 PF13516.6 PXF46146.1 - 0.0023 17.8 0.5 0.45 10.7 0.0 3.8 4 0 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.7 PXF46146.1 - 0.016 15.1 0.2 0.016 15.1 0.2 2.2 2 0 0 2 2 2 0 F-box-like Preseq_ALAS PF09029.10 PXF46146.1 - 0.22 12.0 0.7 0.85 10.1 0.6 2.1 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence UPRTase PF14681.6 PXF46147.1 - 9.1e-65 218.0 0.0 1e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 PXF46147.1 - 6.6e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TP_methylase PF00590.20 PXF46148.1 - 2e-36 126.0 0.3 2.5e-36 125.7 0.3 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Packaging_FI PF14000.6 PXF46148.1 - 0.018 15.5 0.2 0.034 14.6 0.2 1.4 1 0 0 1 1 1 0 DNA packaging protein FI SurA_N PF09312.11 PXF46152.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain AhpC-TSA PF00578.21 PXF46153.1 - 1.6e-28 99.1 0.0 1.9e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PXF46153.1 - 1.6e-16 60.3 0.0 1.7e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 PXF46153.1 - 0.00016 21.8 0.0 0.00021 21.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 PXF46153.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Clathrin PF00637.20 PXF46154.1 - 1.7e-133 439.7 8.3 1.5e-28 99.4 0.0 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PXF46154.1 - 3.7e-18 65.2 0.1 3.6e-17 62.0 0.0 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 PXF46154.1 - 3.5e-13 49.2 0.0 8.7e-05 22.6 0.0 4.6 4 0 0 4 4 4 3 Clathrin propeller repeat TPR_2 PF07719.17 PXF46154.1 - 0.017 15.2 13.8 1.6 9.0 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46154.1 - 0.021 14.7 9.5 4.7 7.2 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Herpes_ori_bp PF02399.15 PXF46154.1 - 0.12 10.4 0.7 0.58 8.1 0.1 2.0 2 0 0 2 2 2 0 Origin of replication binding protein ANAPC3 PF12895.7 PXF46154.1 - 0.18 12.0 4.5 79 3.6 0.1 4.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 PXF46154.1 - 0.47 10.5 3.3 2.2 8.3 0.0 3.3 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_8 PF13181.6 PXF46154.1 - 4.2 7.8 6.4 1e+02 3.5 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BP28CT PF08146.12 PXF46155.1 - 2e-13 50.5 0.4 7.2e-11 42.2 0.0 3.9 2 1 0 3 3 3 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 PXF46155.1 - 0.001 19.4 5.1 2.2 8.7 0.0 5.2 4 1 0 4 4 4 2 HEAT repeats Sua5_yciO_yrdC PF01300.18 PXF46155.1 - 1.5 8.3 4.3 0.9 9.0 1.0 2.3 2 0 0 2 2 2 0 Telomere recombination Exonuc_X-T_C PF08411.10 PXF46156.1 - 0.036 13.2 2.0 0.073 12.2 0.6 2.0 2 0 0 2 2 2 0 Exonuclease C-terminal Fer2 PF00111.27 PXF46157.1 - 5.9e-12 45.4 0.2 8.4e-12 44.9 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SMK-1 PF04802.15 PXF46158.1 - 1.1e-38 133.0 1.8 7.2e-24 84.7 0.1 2.7 2 1 0 2 2 2 2 Component of IIS longevity pathway SMK-1 Pkinase PF00069.25 PXF46158.1 - 6.8e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46158.1 - 2e-17 63.3 0.0 4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF46158.1 - 1.2e-09 37.5 0.1 1.2e-09 37.5 0.1 2.6 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 PXF46158.1 - 7.7e-05 22.7 0.4 0.0017 18.3 0.0 3.0 1 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 PXF46159.1 - 4.7e-67 226.1 0.0 6.1e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46159.1 - 1.7e-36 125.9 0.0 5e-36 124.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF46159.1 - 1.1e-06 28.2 0.3 2.1e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF46159.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like DUF4729 PF15866.5 PXF46159.1 - 0.019 14.3 0.7 0.04 13.2 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Haspin_kinase PF12330.8 PXF46159.1 - 0.027 13.4 0.2 0.04 12.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PXF46159.1 - 0.044 13.7 0.2 0.26 11.2 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF46159.1 - 0.06 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DNA_processg_A PF02481.15 PXF46160.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A Lipoxygenase PF00305.19 PXF46161.1 - 9.8e-49 166.4 0.2 3e-42 144.9 0.1 2.3 2 0 0 2 2 2 2 Lipoxygenase zf-RING_2 PF13639.6 PXF46163.1 - 1.2e-12 47.9 6.2 2.4e-12 47.0 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF46163.1 - 9.1e-11 41.3 1.7 1.9e-10 40.3 1.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 PXF46163.1 - 4.6e-10 39.4 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 PXF46163.1 - 1.9e-08 34.0 5.4 3.6e-08 33.1 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF46163.1 - 6.3e-08 32.4 4.6 1.1e-07 31.5 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46163.1 - 1.4e-07 31.7 4.6 3.9e-07 30.3 4.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF46163.1 - 7.4e-06 25.8 4.2 1.3e-05 25.1 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF46163.1 - 1.1e-05 25.3 0.6 1.1e-05 25.3 0.6 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF46163.1 - 9.4e-05 22.2 5.2 0.0002 21.2 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PXF46163.1 - 0.00024 20.9 3.2 0.00042 20.1 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF46163.1 - 0.0011 19.0 1.1 0.0029 17.6 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 PXF46163.1 - 0.014 15.4 1.4 0.037 14.0 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 PXF46163.1 - 0.047 13.3 3.4 0.12 12.0 3.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PXF46163.1 - 0.07 13.0 4.2 0.13 12.1 4.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 PXF46163.1 - 0.15 11.9 2.6 0.29 11.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 PXF46163.1 - 0.17 12.1 5.1 0.45 10.7 5.1 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 PXF46163.1 - 0.17 12.2 3.5 0.31 11.4 3.5 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 PXF46163.1 - 0.46 10.4 3.5 0.71 9.9 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 PXF46163.1 - 0.79 9.9 5.8 1.2 9.3 3.7 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 PXF46163.1 - 0.94 9.4 3.7 0.22 11.4 0.3 1.7 2 0 0 2 2 1 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 PXF46163.1 - 4.6 7.5 6.1 10 6.4 6.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PXF46163.1 - 5.5 6.9 7.1 1.4 8.8 3.5 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Vps54 PF07928.12 PXF46164.1 - 3.1e-23 82.7 0.0 8.7e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 PXF46164.1 - 7e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HalX PF08663.10 PXF46164.1 - 0.031 14.6 2.8 9.4 6.6 0.1 3.6 2 0 0 2 2 2 0 HalX domain Gly_transf_sug PF04488.15 PXF46165.1 - 9.8e-09 35.7 0.3 3.3e-08 34.0 0.3 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PXF46165.1 - 2e-07 30.7 0.1 3.3e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PXF46165.1 - 0.021 14.2 3.0 0.021 14.1 0.1 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain AI-2E_transport PF01594.16 PXF46166.1 - 9.7e-33 113.7 30.0 8e-32 110.7 30.0 1.9 1 1 0 1 1 1 1 AI-2E family transporter Helicase_C_2 PF13307.6 PXF46167.1 - 1.4e-53 181.6 0.0 3e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PXF46167.1 - 7.2e-44 149.5 1.3 1.2e-43 148.8 1.3 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 PXF46167.1 - 0.015 15.1 0.0 0.85 9.4 0.0 2.6 1 1 0 2 2 2 0 DEAD/DEAH box helicase HBB PF06777.11 PXF46167.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Helical and beta-bridge domain AAA_11 PF13086.6 PXF46167.1 - 0.081 12.7 0.0 1.3 8.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain CinA_KH PF18146.1 PXF46167.1 - 0.11 12.6 0.1 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain ResIII PF04851.15 PXF46167.1 - 0.13 12.2 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Steroid_dh PF02544.16 PXF46168.1 - 5.1e-33 114.2 3.2 8.3e-33 113.5 3.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PXF46168.1 - 4.5e-05 23.1 1.4 8.8e-05 22.1 1.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 PXF46168.1 - 0.0033 17.8 2.7 0.0052 17.2 0.8 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase LisH_2 PF16045.5 PXF46170.1 - 0.052 12.6 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 LisH Pkinase PF00069.25 PXF46171.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46171.1 - 0.0031 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 PXF46172.1 - 3.4e-52 174.2 0.2 7.1e-21 73.8 0.1 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF46172.1 - 1.2e-06 28.6 0.1 0.0063 16.6 0.1 3.2 2 1 1 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 PXF46172.1 - 1.8e-06 27.5 0.0 0.039 13.6 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 PXF46172.1 - 0.011 16.0 0.2 0.78 9.9 0.0 2.8 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF1687 PF07955.11 PXF46172.1 - 0.053 14.0 0.0 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) Cas_Cas2CT1978 PF09707.10 PXF46172.1 - 0.061 13.4 0.0 0.53 10.4 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RSD-2 PF07547.13 PXF46172.1 - 0.16 12.5 0.1 0.48 11.0 0.1 1.9 1 1 0 1 1 1 0 RSD-2 N-terminal domain RRM_occluded PF16842.5 PXF46172.1 - 0.19 11.6 0.0 4.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif Lon_C PF05362.13 PXF46173.1 - 1.1e-74 250.5 0.0 1.9e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 PXF46173.1 - 4.2e-27 95.4 0.0 9.3e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 PXF46173.1 - 4.6e-22 78.9 0.0 1.6e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PXF46173.1 - 1.2e-06 28.5 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PXF46173.1 - 2.5e-06 27.8 2.2 0.0072 16.6 0.0 4.2 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.6 PXF46173.1 - 2.7e-06 27.9 1.2 0.00016 22.1 0.0 3.7 3 2 2 5 5 5 1 AAA ATPase domain ChlI PF13541.6 PXF46173.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 PXF46173.1 - 2.6e-05 23.3 0.0 5.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.14 PXF46173.1 - 4.3e-05 23.7 1.2 0.00054 20.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PXF46173.1 - 5.8e-05 22.9 0.0 0.00026 20.8 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 PXF46173.1 - 0.00039 20.3 0.0 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PXF46173.1 - 0.0013 18.7 0.1 0.42 10.5 0.0 2.6 1 1 1 2 2 2 1 NTPase TIP49 PF06068.13 PXF46173.1 - 0.0047 16.2 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PXF46173.1 - 0.0047 17.5 0.2 0.02 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF46173.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 PXF46173.1 - 0.023 14.7 0.0 0.086 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 PXF46173.1 - 0.027 14.4 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain SKI PF01202.22 PXF46173.1 - 0.062 13.4 0.0 0.062 13.4 0.0 2.4 3 0 0 3 3 2 0 Shikimate kinase AAA_30 PF13604.6 PXF46173.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PXF46173.1 - 0.15 12.4 0.0 0.62 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 PXF46173.1 - 0.18 11.4 0.5 9.5 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PXF46173.1 - 0.2 11.4 4.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PXF46173.1 - 0.22 11.7 1.6 33 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 PXF46173.1 - 0.25 10.8 0.6 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF445 PF04286.12 PXF46173.1 - 0.37 10.6 7.0 0.1 12.4 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) HIP1_clath_bdg PF16515.5 PXF46173.1 - 3.9 8.2 11.4 0.21 12.2 4.9 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WXG100 PF06013.12 PXF46174.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF46174.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF46174.1 - 0.19 12.5 3.7 0.36 11.5 3.7 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DsrD PF08679.11 PXF46175.1 - 0.084 13.1 0.3 1.2 9.5 0.1 2.0 1 1 1 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF3220 PF11516.8 PXF46175.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Med12 PF09497.10 PXF46176.1 - 4e-08 33.4 0.1 1.2e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Tugs PF17840.1 PXF46177.1 - 0.0043 17.2 0.0 0.0063 16.7 0.0 1.3 1 0 0 1 1 1 1 Tethering Ubl4a to BAGS domain ApoLp-III PF07464.11 PXF46177.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Globin PF00042.22 PXF46178.1 - 1.5e-10 41.6 0.0 3.9e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Globin Protoglobin PF11563.8 PXF46178.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Protoglobin PTH2 PF01981.16 PXF46178.1 - 0.065 13.5 0.2 0.13 12.6 0.2 1.5 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 TetR_C_15 PF17918.1 PXF46182.1 - 0.12 13.2 4.3 2.3 9.0 0.1 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L19 PF01245.20 PXF46183.1 - 7.2e-19 67.8 0.0 9.2e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Redoxin PF08534.10 PXF46184.1 - 1e-23 83.7 0.1 1.2e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PXF46184.1 - 9.9e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1403 PF07183.11 PXF46184.1 - 0.062 12.9 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) zf-RING_2 PF13639.6 PXF46185.1 - 8.3e-13 48.4 8.7 1.5e-12 47.6 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF46185.1 - 8.4e-10 38.3 5.6 1.5e-09 37.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF46185.1 - 1.8e-08 34.0 2.0 4.6e-08 32.6 2.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PXF46185.1 - 1.8e-07 30.9 5.4 3.4e-07 30.0 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46185.1 - 1.1e-06 28.8 7.9 5.1e-06 26.7 7.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PXF46185.1 - 3.3e-06 26.8 6.4 6.1e-06 26.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF46185.1 - 1.7e-05 24.7 5.9 3e-05 23.9 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF46185.1 - 9.1e-05 22.4 3.4 0.00026 20.9 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF46185.1 - 0.00011 21.9 5.5 0.00029 20.7 5.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF46185.1 - 0.00023 21.2 1.9 0.00051 20.0 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 PXF46185.1 - 0.012 15.6 1.5 0.03 14.4 1.5 1.8 1 1 0 1 1 1 0 Zinc-finger DZR PF12773.7 PXF46185.1 - 0.045 13.8 1.5 0.1 12.6 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 PXF46185.1 - 0.058 13.0 4.9 0.1 12.3 4.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PXF46185.1 - 0.072 13.2 4.5 0.16 12.1 4.5 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_10 PF16685.5 PXF46185.1 - 0.08 13.1 2.7 0.19 11.9 2.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Ndc1_Nup PF09531.10 PXF46185.1 - 0.19 10.4 7.7 0.23 10.1 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING-like PF08746.11 PXF46185.1 - 0.2 12.0 6.9 0.4 11.0 6.9 1.5 1 0 0 1 1 1 0 RING-like domain Spt20 PF12090.8 PXF46185.1 - 0.26 10.8 26.8 0.38 10.3 26.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF5327 PF17261.2 PXF46185.1 - 0.47 11.2 12.0 0.93 10.3 12.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) zf-RING_4 PF14570.6 PXF46185.1 - 0.68 9.8 6.3 2 8.3 6.3 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PAT1 PF09770.9 PXF46185.1 - 0.84 7.8 19.3 0.91 7.7 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 PXF46185.1 - 0.94 8.9 4.5 1.2 8.6 4.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDRGK PF09756.9 PXF46185.1 - 1.7 8.2 8.5 2.2 7.8 8.5 1.1 1 0 0 1 1 1 0 DDRGK domain PepSY_TM PF03929.16 PXF46185.1 - 2.5 7.7 4.0 3.2 7.3 4.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region TFIIA PF03153.13 PXF46185.1 - 3.5 7.5 29.0 5.5 6.9 29.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PXF46185.1 - 3.6 6.2 11.0 4.4 6.0 11.0 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 PXF46185.1 - 4.8 6.0 13.0 6 5.7 13.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 PXF46185.1 - 5.7 6.9 11.1 7.7 6.5 11.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CCDC53 PF10152.9 PXF46185.1 - 8 6.9 16.7 13 6.2 13.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AAA PF00004.29 PXF46186.1 - 3.2e-27 95.6 0.0 6.1e-18 65.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF46186.1 - 8.3e-07 29.5 0.4 0.015 15.7 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 PXF46186.1 - 2.6e-05 24.0 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 PXF46186.1 - 5.3e-05 23.5 0.0 0.081 13.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF46186.1 - 7.1e-05 23.1 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 PXF46186.1 - 0.00017 21.6 0.4 0.24 11.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PXF46186.1 - 0.00024 21.3 2.0 0.64 10.2 0.1 4.4 3 2 0 3 3 3 1 AAA domain CbiA PF01656.23 PXF46186.1 - 0.00052 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_2 PF07724.14 PXF46186.1 - 0.00069 19.8 0.0 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 PXF46186.1 - 0.00069 19.4 0.2 0.28 10.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Zot PF05707.12 PXF46186.1 - 0.00089 18.9 0.3 0.035 13.7 0.0 2.7 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) RsgA_GTPase PF03193.16 PXF46186.1 - 0.0013 18.6 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activ_2 PF14532.6 PXF46186.1 - 0.0022 18.1 0.0 0.55 10.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 PXF46186.1 - 0.0027 17.2 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 PXF46186.1 - 0.0039 17.2 0.0 0.025 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 PXF46186.1 - 0.0039 17.3 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Torsin ABC_tran PF00005.27 PXF46186.1 - 0.0041 17.6 0.0 5.5 7.5 0.0 3.3 3 0 0 3 3 3 0 ABC transporter Mg_chelatase PF01078.21 PXF46186.1 - 0.0069 15.8 0.0 3.6 6.9 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PXF46186.1 - 0.0076 16.0 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PXF46186.1 - 0.009 15.5 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF2791 PF10923.8 PXF46186.1 - 0.029 13.2 0.2 0.1 11.4 0.1 2.1 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 PXF46186.1 - 0.031 14.2 0.2 0.6 10.0 0.0 2.7 2 1 0 2 2 2 0 NACHT domain TIP49 PF06068.13 PXF46186.1 - 0.032 13.4 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain DUF3135 PF11333.8 PXF46186.1 - 0.035 14.4 0.1 0.098 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PPV_E1_C PF00519.17 PXF46186.1 - 0.05 12.4 0.1 1.8 7.3 0.1 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_25 PF13481.6 PXF46186.1 - 0.06 12.9 0.7 18 4.8 0.1 3.6 2 1 1 3 3 3 0 AAA domain APS_kinase PF01583.20 PXF46186.1 - 0.071 13.0 0.3 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase PIF1 PF05970.14 PXF46186.1 - 0.091 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase RuvB_N PF05496.12 PXF46186.1 - 0.13 12.0 0.0 9.7 5.9 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 PXF46186.1 - 0.14 12.1 0.0 0.47 10.3 0.0 1.9 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 PXF46186.1 - 0.19 11.5 0.1 20 5.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_lid_3 PF17862.1 PXF46186.1 - 0.26 11.2 1.9 0.94 9.3 1.9 1.9 1 0 0 1 1 1 0 AAA+ lid domain AAA_23 PF13476.6 PXF46186.1 - 1.6 9.2 8.2 2.1 8.8 3.8 2.8 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 PXF46186.1 - 2.1 8.9 5.3 4.3 7.9 0.0 3.7 4 1 0 4 4 2 0 AAA domain DNA_pol_E_B PF04042.16 PXF46187.1 - 2.4e-21 76.1 2.7 4.8e-21 75.1 2.7 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 PXF46187.1 - 6.1e-09 36.2 0.0 6.1e-09 36.2 0.0 4.0 3 1 2 5 5 5 1 DNA polymerase alpha subunit B N-terminal Glycolytic PF00274.19 PXF46188.1 - 8.2e-143 475.3 0.0 1e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF5107 PF17128.4 PXF46188.1 - 0.051 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) HECT PF00632.25 PXF46189.1 - 1.5e-92 310.4 0.0 2.3e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3333 PF11812.8 PXF46191.1 - 0.011 16.0 0.7 0.023 14.9 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) DUF2721 PF11026.8 PXF46191.1 - 0.075 12.9 0.3 0.075 12.9 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Spc7 PF08317.11 PXF46191.1 - 0.43 9.4 8.4 0.26 10.1 5.1 1.9 2 1 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 PXF46191.1 - 0.76 9.8 7.7 5.9 6.9 0.3 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.25 PXF46191.1 - 0.86 9.2 7.5 0.19 11.4 2.0 2.5 2 1 0 2 2 2 0 Syntaxin GIT_CC PF16559.5 PXF46191.1 - 1.7 8.6 4.9 6.9 6.6 0.0 3.6 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TFIIA PF03153.13 PXF46191.1 - 5.4 6.9 7.2 7.1 6.5 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PhoLip_ATPase_C PF16212.5 PXF46192.1 - 6.6e-56 189.8 15.6 6.6e-56 189.8 15.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PXF46192.1 - 5.9e-24 83.5 0.8 5.9e-24 83.5 0.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PXF46192.1 - 7.5e-12 45.2 0.0 2.4e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PXF46192.1 - 5.9e-11 43.1 0.6 9.1e-06 26.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PXF46192.1 - 1.4e-08 34.5 2.6 5.4e-08 32.6 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PXF46192.1 - 0.0018 18.1 0.0 0.022 14.5 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF46192.1 - 0.024 15.0 0.0 1 9.7 0.1 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF397 PF04149.12 PXF46198.1 - 0.33 11.1 3.6 1.5 9.0 3.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF397) F-box PF00646.33 PXF46201.1 - 0.00025 20.8 4.0 0.0052 16.6 2.2 3.2 2 1 0 2 2 2 1 F-box domain DUF4239 PF14023.6 PXF46201.1 - 0.038 13.7 2.1 0.097 12.4 0.3 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4239) F-box-like PF12937.7 PXF46201.1 - 0.074 13.0 7.8 0.17 11.8 1.6 3.0 2 1 0 2 2 2 0 F-box-like BCNT PF07572.12 PXF46202.1 - 2.1e-13 50.1 2.6 3.6e-13 49.4 2.6 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development DNA_pol_phi PF04931.13 PXF46202.1 - 0.19 9.8 8.2 0.27 9.3 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 PXF46202.1 - 4.5 6.5 15.2 9.1 5.5 15.2 1.5 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 PXF46202.1 - 9 5.8 12.4 10 5.6 0.2 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Rad21_Rec8_N PF04825.13 PXF46203.1 - 7.8e-34 116.2 0.6 1.5e-33 115.3 0.6 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PXF46203.1 - 4.2e-10 38.8 0.0 1.2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EPL1 PF10513.9 PXF46204.1 - 0.0083 16.5 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 Enhancer of polycomb-like Sua5_yciO_yrdC PF01300.18 PXF46205.1 - 1.5e-54 184.2 0.0 2e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 PXF46205.1 - 2.2e-24 86.5 0.0 3.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding CN_hydrolase PF00795.22 PXF46206.1 - 4e-20 72.3 0.0 4.3e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase COPI_C PF06957.11 PXF46207.1 - 1.1e-14 54.0 0.0 1.1e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Hemerythrin PF01814.23 PXF46208.1 - 0.0012 19.5 0.5 0.043 14.4 0.0 3.2 3 0 0 3 3 3 1 Hemerythrin HHE cation binding domain E1_DerP2_DerF2 PF02221.15 PXF46209.1 - 0.2 12.1 0.1 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 ML domain zf-MYND PF01753.18 PXF46210.1 - 1.2e-09 38.1 9.3 2.5e-09 37.1 9.3 1.6 1 0 0 1 1 1 1 MYND finger zinc_ribbon_4 PF13717.6 PXF46210.1 - 0.0037 17.1 1.5 0.022 14.7 0.2 2.8 3 0 0 3 3 3 1 zinc-ribbon domain zf-Mss51 PF13824.6 PXF46210.1 - 0.0084 16.2 2.0 0.018 15.1 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.12 PXF46210.1 - 0.025 14.6 3.4 0.043 13.8 3.4 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 PXF46210.1 - 4.5 7.5 5.8 12 6.1 5.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Clathrin-link PF09268.10 PXF46212.1 - 2.6e-06 26.7 0.0 4.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Clathrin, heavy-chain linker FAM176 PF14851.6 PXF46213.1 - 0.0057 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 FAM176 family ADIP PF11559.8 PXF46214.1 - 0.017 15.2 0.4 0.034 14.2 0.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1635 PF07795.11 PXF46214.1 - 0.28 11.0 1.5 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DDE_Tnp_4 PF13359.6 PXF46215.1 - 1.6e-24 86.4 0.0 2.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PXF46215.1 - 6.3e-05 22.7 0.1 0.00036 20.3 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain RNA_pol_Rpb2_4 PF04566.13 PXF46215.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Peptidase_U57 PF05582.12 PXF46216.1 - 0.062 12.6 3.2 0.099 11.9 3.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 PsbN PF02468.15 PXF46220.1 - 0.23 11.4 0.5 0.45 10.4 0.5 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) AIG1 PF04548.16 PXF46221.1 - 9.2e-09 34.9 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 AIG1 family T2SSE PF00437.20 PXF46221.1 - 0.00039 19.6 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 PXF46221.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 PXF46221.1 - 0.081 13.3 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 PXF46221.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.15 PXF46221.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 PXF46221.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family W2 PF02020.18 PXF46222.1 - 1.4e-20 73.2 0.2 2.9e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon SurA_N PF09312.11 PXF46222.1 - 0.016 15.2 0.1 0.05 13.7 0.1 1.8 1 0 0 1 1 1 0 SurA N-terminal domain Tn7_Tnp_TnsA_C PF08721.11 PXF46222.1 - 0.16 12.6 0.5 15 6.3 0.0 3.2 3 0 0 3 3 3 0 TnsA endonuclease C terminal AMPK1_CBM PF16561.5 PXF46223.1 - 3.5e-17 62.4 0.0 1.6e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase TPR_8 PF13181.6 PXF46223.1 - 2.8e-11 42.7 3.3 0.029 14.6 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF46223.1 - 1.6e-10 41.1 5.6 0.0008 19.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46223.1 - 1.6e-05 24.5 3.5 0.017 14.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46223.1 - 2.9e-05 24.5 3.2 0.52 11.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF46223.1 - 3.7e-05 23.4 4.3 0.16 11.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF46223.1 - 4.8e-05 23.8 1.7 0.075 13.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46223.1 - 0.00025 20.9 7.4 0.039 14.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 PXF46223.1 - 0.00058 19.8 3.3 0.0023 17.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46223.1 - 0.0012 18.5 5.2 0.21 11.3 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.6 PXF46223.1 - 0.015 15.9 0.5 2.7 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 PXF46223.1 - 0.02 14.3 0.1 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP CBM_48 PF02922.18 PXF46223.1 - 0.029 14.7 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TPR_17 PF13431.6 PXF46223.1 - 0.058 13.8 0.1 2.7 8.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46223.1 - 0.058 13.4 1.9 8.5 6.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.13 PXF46223.1 - 0.07 12.9 0.3 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF410) ANAPC3 PF12895.7 PXF46223.1 - 0.085 13.1 4.6 0.73 10.1 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 PXF46223.1 - 3.8 7.6 6.3 37 4.5 0.1 3.4 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain DDE_1 PF03184.19 PXF46225.1 - 2.6e-15 56.5 0.0 3.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 PXF46225.1 - 6.4e-05 22.7 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease TPR_11 PF13414.6 PXF46226.1 - 0.0066 16.1 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 PXF46226.1 - 0.017 15.4 5.3 0.14 12.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46226.1 - 0.16 12.1 1.3 0.86 9.9 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 PXF46226.1 - 0.38 11.1 1.3 0.65 10.4 0.1 2.1 2 0 0 2 2 2 0 PPR repeat Hint PF01079.20 PXF46231.1 - 4.4e-17 62.3 0.0 8.2e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Hint module adh_short_C2 PF13561.6 PXF46232.1 - 3.7e-47 160.8 0.3 6e-45 153.6 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PXF46232.1 - 9.7e-42 142.6 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PXF46232.1 - 7.1e-09 35.8 0.7 1.1e-08 35.3 0.7 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PXF46232.1 - 9.5e-07 28.5 0.1 1.8e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 PXF46232.1 - 0.21 11.4 3.2 0.62 9.9 3.2 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NB-ARC PF00931.22 PXF46233.1 - 4e-14 52.4 0.0 7.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PQQ_2 PF13360.6 PXF46233.1 - 2.1e-06 27.5 2.1 0.0011 18.6 0.5 3.6 3 1 1 4 4 4 2 PQQ-like domain WD40 PF00400.32 PXF46233.1 - 5.9e-06 26.9 25.2 0.00077 20.2 1.7 9.6 10 0 0 10 10 10 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46233.1 - 0.00046 20.4 0.1 2.2 8.6 0.0 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PilJ PF13675.6 PXF46233.1 - 0.0044 17.0 0.7 0.01 15.9 0.7 1.6 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term APAF1_C PF17908.1 PXF46233.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 APAF-1 helical domain AAA_16 PF13191.6 PXF46233.1 - 0.084 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Syntaxin_2 PF14523.6 PXF46233.1 - 0.14 12.5 1.9 0.45 10.9 1.9 1.9 1 0 0 1 1 1 0 Syntaxin-like protein AMPK1_CBM PF16561.5 PXF46234.1 - 1.2e-19 70.3 0.5 1.9e-19 69.6 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 PXF46234.1 - 0.052 14.1 1.2 0.1 13.2 1.2 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) TRAPPC9-Trs120 PF08626.11 PXF46234.1 - 0.29 8.4 0.7 0.4 8.0 0.7 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_transf_7C PF02709.14 PXF46235.1 - 1.4e-07 31.0 0.2 3.2e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PXF46235.1 - 3.3e-05 23.9 0.1 0.00011 22.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF46235.1 - 5.7e-05 22.7 0.2 0.00015 21.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 O-FucT PF10250.9 PXF46235.1 - 0.00014 21.7 0.3 0.00084 19.1 0.3 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glycos_transf_2 PF00535.26 PXF46235.1 - 0.00018 21.4 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 NodZ PF05830.11 PXF46235.1 - 0.00026 19.9 0.0 0.21 10.4 0.0 2.5 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PXF46235.1 - 0.026 13.2 0.0 2.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase adh_short PF00106.25 PXF46236.1 - 8.8e-43 146.0 0.2 1.2e-42 145.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF46236.1 - 5e-25 88.4 0.4 6.8e-25 88.0 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF46236.1 - 6.4e-11 42.5 1.0 9.7e-11 41.9 1.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF46236.1 - 2.2e-07 31.0 0.1 2.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PXF46236.1 - 3.5e-05 23.1 0.1 4.1e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PXF46236.1 - 0.00014 21.4 0.6 0.00026 20.5 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF46236.1 - 0.0083 15.6 0.6 0.038 13.4 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 PXF46236.1 - 0.012 15.6 0.2 0.059 13.3 0.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family CoA_binding_2 PF13380.6 PXF46236.1 - 0.067 13.7 0.2 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 CoA binding domain RmlD_sub_bind PF04321.17 PXF46236.1 - 0.085 11.9 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CnrY PF17524.2 PXF46236.1 - 0.48 10.7 2.4 3.6 7.9 0.3 2.7 2 0 0 2 2 2 0 Anti-sigma factor CnrY adh_short PF00106.25 PXF46237.1 - 3e-39 134.5 0.0 3.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF46237.1 - 2.4e-21 76.4 0.0 3.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMPK1_CBM PF16561.5 PXF46237.1 - 2e-16 60.0 0.1 3.3e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase KR PF08659.10 PXF46237.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_90 PF05686.12 PXF46238.1 - 1.2e-26 93.6 0.0 2.2e-26 92.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 TIG PF01833.24 PXF46239.1 - 4.2e-18 65.2 9.1 1.3e-09 38.0 0.1 3.8 5 0 0 5 5 5 2 IPT/TIG domain HYR PF02494.16 PXF46239.1 - 0.0085 16.4 0.3 0.024 15.0 0.3 1.8 1 0 0 1 1 1 1 HYR domain Fungal_lectin PF07938.12 PXF46239.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal fucose-specific lectin Qn_am_d_aIII PF09099.10 PXF46239.1 - 0.29 11.5 1.7 16 6.0 0.0 3.4 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III zf-MYND PF01753.18 PXF46240.1 - 1.8e-08 34.3 12.5 1.8e-08 34.3 12.5 2.2 2 0 0 2 2 2 1 MYND finger SPATA3 PF15662.5 PXF46240.1 - 0.007 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 3 family Borrelia_REV PF03978.13 PXF46240.1 - 0.032 14.2 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF5638 PF18688.1 PXF46240.1 - 0.068 13.5 0.9 0.18 12.1 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5638) zf-Mss51 PF13824.6 PXF46240.1 - 0.11 12.7 6.1 0.28 11.3 6.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Copine PF07002.16 PXF46241.1 - 8.6e-64 215.0 0.1 1.2e-63 214.5 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 PXF46241.1 - 1.7e-08 34.7 0.0 1.4e-05 25.3 0.0 3.4 3 0 0 3 3 3 1 C2 domain vWA-TerF-like PF10138.9 PXF46241.1 - 0.0045 17.1 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 PXF46241.1 - 0.098 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain tRNA-synt_1 PF00133.22 PXF46242.1 - 1.2e-25 89.9 0.0 1.2e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DUF2846 PF11008.8 PXF46242.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) tRNA-synt_1 PF00133.22 PXF46243.1 - 1.6e-80 271.1 0.1 1.9e-80 270.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF46243.1 - 8.1e-08 31.4 0.1 0.00027 19.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 PXF46243.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Glyoxalase PF00903.25 PXF46244.1 - 2.4e-09 37.5 0.2 1.1e-08 35.4 0.0 2.2 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_1 PF00036.32 PXF46244.1 - 8.7e-09 34.3 0.1 3.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PXF46244.1 - 3.9e-06 26.3 0.1 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PXF46244.1 - 1.6e-05 24.7 0.1 0.00019 21.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PXF46244.1 - 2.8e-05 24.5 0.1 0.016 15.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Glyoxalase_4 PF13669.6 PXF46244.1 - 0.0052 17.1 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF46244.1 - 0.042 14.6 0.0 0.12 13.1 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain EF-hand_5 PF13202.6 PXF46244.1 - 0.046 13.2 1.0 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 EF hand Glyoxalase_2 PF12681.7 PXF46244.1 - 0.17 11.8 0.2 23 4.9 0.0 2.6 3 0 0 3 3 3 0 Glyoxalase-like domain NGP1NT PF08153.12 PXF46245.1 - 3.3e-42 143.7 0.9 5.6e-42 143.0 0.9 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 PXF46245.1 - 2e-17 63.3 0.0 1.9e-14 53.7 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF46245.1 - 5.4e-07 29.3 0.1 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PXF46245.1 - 2.1e-06 27.8 0.0 6.7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 PXF46245.1 - 0.0053 16.2 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 PXF46245.1 - 0.22 11.6 0.1 0.22 11.6 0.1 4.2 4 2 1 5 5 5 0 Dynamin family Mis14 PF08641.12 PXF46245.1 - 7.1 7.0 10.4 0.14 12.5 3.0 1.9 2 0 0 2 2 2 0 Kinetochore protein Mis14 like RRM_1 PF00076.22 PXF46246.1 - 1.7e-27 95.0 0.0 2.5e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF46246.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Collagen PF01391.18 PXF46247.1 - 2.7e-05 23.8 16.5 2.7e-05 23.8 16.5 2.5 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) SRP-alpha_N PF04086.13 PXF46247.1 - 0.0065 16.4 41.0 0.01 15.8 41.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Utp14 PF04615.13 PXF46247.1 - 0.0068 15.0 45.6 0.0094 14.6 45.6 1.1 1 0 0 1 1 1 1 Utp14 protein Nop14 PF04147.12 PXF46247.1 - 0.02 13.1 41.6 0.035 12.3 41.6 1.3 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 PXF46247.1 - 1.6 7.2 28.0 2.2 6.7 28.0 1.2 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 PXF46247.1 - 1.8 7.6 32.3 2.6 7.1 32.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ArfGap PF01412.18 PXF46248.1 - 1.4e-17 63.9 0.0 1.4e-17 63.9 0.0 2.8 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf PAP_PilO PF06864.12 PXF46249.1 - 0.058 12.2 0.0 0.058 12.2 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) EpmC PF04315.12 PXF46249.1 - 0.14 11.8 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Elongation factor P hydroxylase Kinesin PF00225.23 PXF46250.1 - 3.8e-104 348.2 0.1 8.2e-104 347.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF46250.1 - 2.5e-45 154.1 0.0 6.8e-45 152.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding CBM_20 PF00686.19 PXF46250.1 - 1.4e-09 37.7 0.0 3.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain PLAT PF01477.23 PXF46250.1 - 0.00028 21.4 0.0 0.00067 20.2 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain FUSC PF04632.12 PXF46250.1 - 5.7 5.4 29.0 0.2 10.2 14.5 2.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Lycopene_cycl PF05834.12 PXF46251.1 - 3.5e-93 312.7 0.0 4.1e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 PXF46251.1 - 1.8e-06 27.4 0.0 0.00074 18.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 PXF46251.1 - 2.2e-05 23.8 0.0 3.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF46251.1 - 0.00018 20.7 0.2 0.00035 19.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PXF46251.1 - 0.0002 21.1 0.6 0.013 15.2 0.1 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 PXF46251.1 - 0.00033 19.9 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 PXF46251.1 - 0.00033 20.0 0.0 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 PXF46251.1 - 0.00041 19.3 0.8 0.047 12.5 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 PXF46251.1 - 0.00072 19.7 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PXF46251.1 - 0.00093 18.0 0.0 0.0019 17.0 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 PXF46251.1 - 0.0019 17.4 0.0 0.081 12.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A PaaA_PaaC PF05138.12 PXF46251.1 - 0.015 14.5 0.0 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein Pyr_redox PF00070.27 PXF46251.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF46251.1 - 0.044 13.8 0.8 0.42 10.6 0.8 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PXF46251.1 - 0.082 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PPTA PF01239.22 PXF46252.1 - 0.0024 17.6 0.1 0.0024 17.6 0.1 4.4 6 0 0 6 6 6 1 Protein prenyltransferase alpha subunit repeat Herpes_UL52 PF03121.15 PXF46253.1 - 2.7e-11 43.2 0.0 8.9e-11 41.6 0.0 2.0 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase PIN_4 PF13638.6 PXF46254.1 - 0.046 14.0 0.4 0.062 13.6 0.4 1.4 1 1 0 1 1 1 0 PIN domain EMP24_GP25L PF01105.24 PXF46255.1 - 4.5e-37 127.7 0.6 4.5e-37 127.7 0.6 1.7 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD TBCC_N PF16752.5 PXF46255.1 - 0.19 12.2 0.8 0.27 11.7 0.1 1.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF3067 PF11267.8 PXF46256.1 - 4.5e-27 94.5 0.0 6.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) zinc-ribbons_6 PF07191.12 PXF46256.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbons PduV-EutP PF10662.9 PXF46256.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-binding PF00249.31 PXF46257.1 - 2.3e-10 40.5 0.1 4.1e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF46257.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF46257.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Myb DNA-binding like WIYLD PF10440.9 PXF46257.1 - 0.19 11.6 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain SNF2_N PF00176.23 PXF46259.1 - 2.6e-66 223.7 0.1 5.3e-66 222.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 PXF46259.1 - 2.8e-25 89.2 16.9 2.8e-25 89.2 16.9 2.3 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 PXF46259.1 - 1.3e-17 64.1 0.0 5.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF46259.1 - 9.8e-09 35.4 0.4 3.9e-06 27.0 0.0 3.1 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF46259.1 - 6.6e-06 26.0 0.0 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase NUDIX PF00293.28 PXF46260.1 - 8.4e-15 55.0 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AHH PF14412.6 PXF46260.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4407 PF14362.6 PXF46261.1 - 0.4 10.0 3.6 0.54 9.6 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 PXF46261.1 - 1.6 9.0 8.8 1.8 8.8 5.1 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 PXF46261.1 - 3.7 5.3 7.8 2.2 6.1 5.4 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PCI PF01399.27 PXF46262.1 - 0.015 15.8 0.0 0.015 15.8 0.0 4.5 6 0 0 6 6 6 0 PCI domain GRAM PF02893.20 PXF46263.1 - 0.0043 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain GST_N_3 PF13417.6 PXF46264.1 - 4.5e-30 103.9 0.0 6e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF46264.1 - 7.4e-16 58.2 0.0 3.4e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PXF46264.1 - 4.6e-09 36.5 0.0 7e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain CP12 PF02672.15 PXF46264.1 - 7.2e-07 29.9 2.4 1.3e-06 29.1 2.4 1.4 1 0 0 1 1 1 1 CP12 domain Glutaredoxin PF00462.24 PXF46264.1 - 2.5e-06 27.6 0.1 0.002 18.3 0.1 2.4 2 0 0 2 2 2 2 Glutaredoxin Utp21 PF04192.12 PXF46266.1 - 7.7e-42 143.4 1.1 1.4e-41 142.6 1.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 PXF46266.1 - 6.9e-16 58.4 14.7 0.00084 20.1 0.0 8.7 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46266.1 - 3.1e-13 49.8 0.0 1.8e-05 24.9 0.0 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF46266.1 - 0.0023 17.3 0.1 0.032 13.6 0.1 2.6 2 1 0 2 2 2 1 WD40-like domain Frtz PF11768.8 PXF46266.1 - 0.15 10.3 0.0 0.71 8.1 0.0 2.0 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 PXF46266.1 - 1.2 9.2 3.7 46 4.2 0.2 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 PXF46266.1 - 4.1 8.0 6.4 2.4 8.7 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain NPL PF17800.1 PXF46267.1 - 1.3e-16 61.0 0.0 1.3e-16 61.0 0.0 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 PXF46267.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain Queuosine_synth PF02547.15 PXF46268.1 - 5.1e-101 338.1 0.0 1.3e-100 336.7 0.0 1.5 1 1 0 1 1 1 1 Queuosine biosynthesis protein Methyltransf_23 PF13489.6 PXF46269.1 - 1.5e-05 24.9 0.0 4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF46269.1 - 4.5e-05 22.9 0.0 9.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 PXF46269.1 - 0.00022 21.9 0.2 0.0011 19.6 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PXF46269.1 - 0.00028 20.5 0.1 0.0067 16.0 0.1 2.5 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PXF46269.1 - 0.00048 20.0 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PXF46269.1 - 0.0011 18.5 0.4 0.002 17.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 PXF46269.1 - 0.0053 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 PXF46269.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 PXF46269.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NTP_transferase PF00483.23 PXF46270.1 - 3.8e-07 29.9 0.0 4.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 PXF46270.1 - 0.008 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Linker_histone PF00538.19 PXF46270.1 - 0.058 13.8 0.0 0.39 11.1 0.0 2.4 3 0 0 3 3 3 0 linker histone H1 and H5 family DUF3829 PF12889.7 PXF46270.1 - 0.11 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Epimerase PF01370.21 PXF46271.1 - 1.7e-22 80.0 0.0 3.6e-22 79.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF46271.1 - 9.8e-15 54.3 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF46271.1 - 1.4e-12 47.9 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PXF46271.1 - 1.4e-09 37.5 0.0 1.7e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 PXF46271.1 - 6.1e-09 35.7 0.0 9.5e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PXF46271.1 - 2e-08 34.1 0.0 4.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 PXF46271.1 - 5.1e-05 22.8 0.0 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PXF46271.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PXF46271.1 - 0.034 13.3 0.1 0.26 10.4 0.1 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Acetyltransf_1 PF00583.25 PXF46272.1 - 4.9e-07 30.0 0.0 8.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF46272.1 - 7.3e-06 26.3 0.1 1.5e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF46272.1 - 0.00048 20.8 0.0 0.00066 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF46272.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 PXF46272.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_10 PF13673.7 PXF46272.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2 PF00152.20 PXF46273.1 - 1.6e-105 352.7 0.0 1.9e-105 352.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 PXF46273.1 - 7.1e-16 58.2 0.0 1.4e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 PXF46273.1 - 2.7e-12 46.5 1.5 6.9e-12 45.2 1.5 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF46273.1 - 0.00013 21.5 0.3 0.01 15.3 0.1 2.7 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) DUF1365 PF07103.11 PXF46274.1 - 2.8e-60 204.0 0.1 3.4e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) L51_S25_CI-B8 PF05047.16 PXF46275.1 - 1.8e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Cyclin_N PF00134.23 PXF46276.1 - 4.6e-14 52.2 1.3 1.2e-12 47.6 0.6 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF46276.1 - 0.007 16.4 0.1 0.007 16.4 0.1 2.5 2 1 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 PXF46276.1 - 0.012 16.0 3.4 0.017 15.5 0.4 2.8 2 2 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 PXF46276.1 - 0.021 14.8 1.2 0.12 12.4 0.7 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Sec1 PF00995.23 PXF46276.1 - 0.19 10.9 2.1 0.71 9.0 0.1 1.9 1 1 0 2 2 2 0 Sec1 family MFS_1 PF07690.16 PXF46277.1 - 6.6e-46 156.8 39.1 1.6e-45 155.6 35.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 PXF46277.1 - 3.7e-07 29.1 11.5 3.4e-06 26.0 11.5 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 PXF46277.1 - 0.00014 20.9 25.6 0.0008 18.4 19.4 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter PPR_2 PF13041.6 PXF46278.1 - 6.7e-52 173.5 2.1 3.5e-16 59.1 0.0 8.2 3 2 5 8 8 8 7 PPR repeat family PPR PF01535.20 PXF46278.1 - 1.1e-41 138.2 10.0 1.7e-09 37.3 0.0 9.7 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.6 PXF46278.1 - 6.6e-39 131.8 0.0 6.7e-10 38.9 0.0 6.7 4 2 4 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF46278.1 - 1.2e-34 117.7 0.8 7.4e-10 38.4 0.0 6.6 6 0 0 6 6 6 6 PPR repeat PPR_long PF17177.4 PXF46278.1 - 1.8e-23 83.0 0.0 5.1e-08 32.5 0.1 4.2 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 PXF46278.1 - 0.019 15.0 0.0 4.5 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ApoC-I PF04691.12 PXF46278.1 - 0.21 11.5 0.3 9 6.3 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) WD40 PF00400.32 PXF46279.1 - 4.6e-54 179.2 6.3 7.5e-08 32.9 0.0 10.7 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46279.1 - 3.7e-17 62.4 0.1 0.16 12.3 0.0 8.6 6 2 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PXF46279.1 - 1.3e-11 44.8 0.8 3.7e-11 43.3 0.8 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 PXF46279.1 - 1.6e-05 23.8 0.0 1.1 7.8 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PXF46279.1 - 1.8e-05 23.9 0.1 4.2 6.2 0.0 5.8 5 1 2 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PXF46279.1 - 0.00015 21.2 0.0 0.96 8.7 0.0 3.6 4 0 0 4 4 4 2 WD40-like domain Ferlin_C PF16165.5 PXF46279.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Ferlin C-terminus Nucleoporin_N PF08801.11 PXF46279.1 - 0.21 10.3 0.1 43 2.7 0.0 3.9 2 2 2 4 4 4 0 Nup133 N terminal like DUF1825 PF08855.10 PXF46280.1 - 4e-26 90.9 2.1 4.5e-26 90.7 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) DUF3288 PF11691.8 PXF46280.1 - 0.061 13.4 0.1 0.5 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3288) Ank_2 PF12796.7 PXF46281.1 - 1.1e-44 150.9 11.0 1.3e-19 70.5 0.7 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF46281.1 - 2e-33 114.3 10.7 1.6e-10 41.3 0.1 7.2 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PXF46281.1 - 2.6e-29 100.3 18.8 5.5e-05 23.4 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 PXF46281.1 - 1.8e-28 95.4 11.3 0.00072 19.8 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 PXF46281.1 - 8.8e-24 83.3 14.7 1.7e-06 28.2 0.5 5.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Exo_endo_phos PF03372.23 PXF46282.1 - 3.8e-07 29.9 0.2 9.5e-07 28.6 0.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HHH_6 PF14579.6 PXF46282.1 - 0.00088 19.5 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Exo_endo_phos_2 PF14529.6 PXF46282.1 - 0.005 16.7 0.1 0.032 14.1 0.1 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase PfkB PF00294.24 PXF46283.1 - 2.6e-66 224.0 0.1 3.3e-66 223.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PXF46283.1 - 0.0022 17.4 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase LsmAD PF06741.13 PXF46284.1 - 6.4e-23 81.1 3.7 6.4e-23 81.1 3.7 2.6 2 0 0 2 2 2 1 LsmAD domain PAM2 PF07145.15 PXF46284.1 - 0.016 14.9 9.0 0.026 14.2 1.8 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Enkurin PF13864.6 PXF46284.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.1 3 0 0 3 3 3 0 Calmodulin-binding PDCD2_C PF04194.13 PXF46285.1 - 7.1e-37 127.2 11.3 4.1e-34 118.2 6.6 3.0 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 PXF46285.1 - 1.1e-08 35.1 9.8 1.1e-08 35.1 9.8 3.0 4 0 0 4 4 4 1 MYND finger FTH PF01827.27 PXF46285.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 FTH domain GDP_Man_Dehyd PF16363.5 PXF46286.1 - 1.8e-54 185.4 0.0 2.1e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF46286.1 - 7.3e-48 163.1 0.0 8.6e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF46286.1 - 4e-12 45.7 0.0 2.5e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PXF46286.1 - 4.7e-11 42.4 0.0 2.7e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PXF46286.1 - 2.7e-08 33.3 0.0 3.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 PXF46286.1 - 2.6e-07 30.3 0.0 7.3e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PXF46286.1 - 6.1e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 PXF46286.1 - 9e-05 21.8 0.1 0.0081 15.4 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein DUF3013 PF11217.8 PXF46286.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) Hint PF01079.20 PXF46287.1 - 2.6e-31 108.8 0.0 4.2e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Hint module Hom_end_hint PF05203.16 PXF46287.1 - 0.0028 17.6 0.1 0.0079 16.2 0.0 1.6 1 1 1 2 2 2 1 Hom_end-associated Hint Intein_splicing PF14890.6 PXF46287.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Intein splicing domain Epimerase PF01370.21 PXF46288.1 - 4.7e-09 36.1 0.0 0.00026 20.5 0.0 2.5 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF46288.1 - 8.9e-08 31.9 0.0 0.0035 16.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 PXF46288.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 PXF46288.1 - 0.14 12.1 0.6 0.46 10.3 0.6 2.1 1 1 0 1 1 1 0 NAD(P)H-binding Rab5ip PF07019.12 PXF46289.1 - 1e-13 51.6 3.0 1.6e-13 51.1 3.0 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SafA PF17073.5 PXF46289.1 - 0.088 12.8 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Two-component-system connector protein DUF2607 PF10795.9 PXF46289.1 - 0.21 11.8 1.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) DUF1713 PF08213.11 PXF46290.1 - 1.7e-08 34.2 19.0 2.8e-08 33.6 19.0 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) His_Phos_1 PF00300.22 PXF46292.1 - 1.3e-07 31.5 0.0 5.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RRN3 PF05327.11 PXF46293.1 - 0.021 13.4 2.8 0.033 12.7 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Plant_tran PF04827.14 PXF46294.1 - 6.5e-35 120.6 0.0 8.5e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF46294.1 - 5.1e-08 32.7 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 PXF46294.1 - 0.061 13.7 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain H_PPase PF03030.16 PXF46298.1 - 5.3e-13 48.5 6.5 5.3e-13 48.5 6.5 1.8 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase SPT_ssu-like PF11779.8 PXF46298.1 - 0.059 13.0 4.5 0.24 11.0 0.1 2.7 3 0 0 3 3 3 0 Small subunit of serine palmitoyltransferase-like G-patch PF01585.23 PXF46299.1 - 2.4e-12 46.5 1.8 2.4e-12 46.5 1.8 2.1 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 PXF46299.1 - 7.6e-09 35.5 0.8 7.6e-09 35.5 0.8 2.7 2 1 0 2 2 2 1 G-patch domain Methyltransf_12 PF08242.12 PXF46300.1 - 7.7e-08 33.0 0.1 8.3e-06 26.5 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46300.1 - 2.2e-07 31.5 0.0 0.0011 19.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46300.1 - 1e-06 28.6 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PXF46300.1 - 4.7e-05 23.9 0.1 0.084 13.5 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 PXF46300.1 - 0.00028 20.8 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 PXF46300.1 - 0.0004 20.1 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PgpA PF04608.13 PXF46300.1 - 0.0067 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A RrnaAD PF00398.20 PXF46300.1 - 0.013 14.5 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 PXF46300.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Baculo_PEP_C PF04513.12 PXF46301.1 - 0.00075 19.6 4.9 0.0039 17.2 4.6 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Poty_PP PF08440.10 PXF46301.1 - 0.076 12.1 5.3 0.11 11.5 5.3 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein Fib_alpha PF08702.10 PXF46301.1 - 0.98 9.6 12.4 0.41 10.8 2.7 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 PXF46301.1 - 1.2 9.2 7.6 1.4 9.0 0.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 PXF46301.1 - 1.7 9.2 6.4 20 5.8 0.5 3.5 2 1 2 4 4 4 0 Histidine kinase Lectin_N PF03954.14 PXF46301.1 - 2 8.2 8.1 0.39 10.5 3.4 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Prominin PF05478.11 PXF46301.1 - 8.2 4.2 11.7 0.89 7.4 3.5 1.9 1 1 1 2 2 2 0 Prominin CCT PF06203.14 PXF46302.1 - 5.2e-14 52.0 17.2 7.5e-14 51.5 17.2 1.2 1 0 0 1 1 1 1 CCT motif NUC173 PF08161.12 PXF46304.1 - 6.3e-28 97.8 1.2 7.8e-27 94.3 0.0 3.0 3 0 0 3 3 3 1 NUC173 domain DUF5539 PF17693.1 PXF46304.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Importin_rep_5 PF18816.1 PXF46304.1 - 1.1 9.6 4.6 0.97 9.8 0.3 3.1 3 0 0 3 3 3 0 Importin repeat Rsa3 PF14615.6 PXF46307.1 - 4.3e-09 35.8 0.1 8.7e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DNA_ligase_A_M PF01068.21 PXF46308.1 - 1.8e-30 106.2 0.1 3.2e-30 105.3 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 PXF46308.1 - 1.1e-13 51.4 0.1 7.6e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_N PF04675.14 PXF46308.1 - 1.3e-10 41.9 0.0 5.2e-09 36.7 0.0 2.7 2 1 0 2 2 2 1 DNA ligase N terminus BRCT PF00533.26 PXF46308.1 - 5.5e-08 33.1 0.2 0.00014 22.2 0.1 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 PXF46308.1 - 1e-07 32.4 0.1 2.7e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 PXF46308.1 - 1.7e-07 31.7 0.1 1.7e-07 31.7 0.1 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region PTCB-BRCT PF12738.7 PXF46308.1 - 0.0065 16.4 0.0 0.047 13.7 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 PXF46308.1 - 0.097 13.0 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Ribosomal_L29e PF01779.17 PXF46309.1 - 1.5e-20 73.2 11.5 2.1e-20 72.7 11.5 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family CCT PF06203.14 PXF46310.1 - 7.2e-15 54.8 11.4 9.3e-15 54.4 11.4 1.1 1 0 0 1 1 1 1 CCT motif Mito_fiss_reg PF05308.11 PXF46310.1 - 0.055 13.6 2.0 0.06 13.4 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Esterase PF00756.20 PXF46311.1 - 0.00024 20.9 0.0 0.00088 19.0 0.0 1.9 2 0 0 2 2 2 1 Putative esterase AIG2_2 PF13772.6 PXF46311.1 - 0.00079 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family DAGAT PF03982.13 PXF46311.1 - 0.00093 18.2 0.0 0.0028 16.6 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Abhydrolase_3 PF07859.13 PXF46311.1 - 0.0057 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF46311.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 PXF46311.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 PXF46311.1 - 0.03 14.0 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Acyltransferase PF01553.21 PXF46311.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase PGAP1 PF07819.13 PXF46311.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 PXF46311.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGM_PMM_I PF02878.16 PXF46312.1 - 5.1e-29 100.7 0.0 9.1e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PXF46312.1 - 9.9e-28 96.6 0.0 2.8e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PXF46312.1 - 7.3e-12 45.8 0.1 2e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PXF46312.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acyltransferase PF01553.21 PXF46313.1 - 9.6e-14 51.2 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 PXF46313.1 - 1.3e-09 38.0 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF3591 PF12157.8 PXF46313.1 - 0.00045 19.0 0.0 0.00066 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) DUF1405 PF07187.11 PXF46313.1 - 0.49 10.4 4.1 8.6 6.3 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1405) BORCS8 PF10167.9 PXF46316.1 - 0.032 14.2 0.9 0.28 11.2 0.3 2.1 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 ACR_tran PF00873.19 PXF46316.1 - 0.069 10.8 0.2 0.088 10.4 0.2 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Nse4_C PF08743.10 PXF46317.1 - 2.5e-21 75.7 0.1 2.5e-21 75.7 0.1 2.0 2 0 0 2 2 2 1 Nse4 C-terminal ParB PF08775.10 PXF46317.1 - 0.067 13.7 3.2 0.14 12.6 3.2 1.6 1 0 0 1 1 1 0 ParB family Pet100 PF09803.9 PXF46317.1 - 4.9 7.7 6.9 31 5.2 0.2 3.3 3 0 0 3 3 3 0 Pet100 ABM PF03992.16 PXF46318.1 - 0.0022 18.1 0.7 0.026 14.6 0.1 2.5 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase BATS PF06968.13 PXF46319.1 - 5.2e-19 68.2 0.0 9.6e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 PXF46319.1 - 8.2e-13 49.1 0.1 1.2e-12 48.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pro_isomerase PF00160.21 PXF46320.1 - 7.1e-44 149.9 0.1 8.3e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PEARLI-4 PF05278.12 PXF46321.1 - 0.0001 22.0 9.0 0.0002 21.1 9.0 1.4 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) Fez1 PF06818.15 PXF46321.1 - 0.001 19.5 10.9 0.0014 19.1 10.9 1.1 1 0 0 1 1 1 1 Fez1 DUF3584 PF12128.8 PXF46321.1 - 0.0055 14.3 8.5 0.0066 14.0 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 PXF46321.1 - 0.0088 15.0 14.2 0.013 14.4 14.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein YabA PF06156.13 PXF46321.1 - 0.012 16.3 10.9 0.38 11.4 4.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA phiKZ_IP PF12699.7 PXF46321.1 - 0.018 14.2 11.4 1.9 7.6 0.0 3.0 1 1 2 3 3 3 0 phiKZ-like phage internal head proteins Golgin_A5 PF09787.9 PXF46321.1 - 0.023 14.2 11.6 0.039 13.4 11.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 PXF46321.1 - 0.024 13.8 10.8 0.031 13.4 10.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 PXF46321.1 - 0.025 14.8 7.2 0.044 14.0 7.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LPP PF04728.13 PXF46321.1 - 0.027 14.9 4.8 1.6 9.2 0.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper End3 PF12761.7 PXF46321.1 - 0.04 14.1 12.3 0.059 13.5 12.3 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 EzrA PF06160.12 PXF46321.1 - 0.047 11.9 8.9 0.068 11.3 8.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.21 PXF46321.1 - 0.09 12.3 15.8 0.19 11.3 11.2 2.0 1 1 1 2 2 2 0 Intermediate filament protein GAS PF13851.6 PXF46321.1 - 0.092 12.1 14.4 0.14 11.5 14.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PilJ PF13675.6 PXF46321.1 - 0.093 12.8 0.3 0.093 12.8 0.3 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Dam1 PF08653.10 PXF46321.1 - 0.15 11.9 1.3 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4407 PF14362.6 PXF46321.1 - 0.17 11.2 11.0 0.44 9.8 11.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 PXF46321.1 - 0.19 12.0 7.9 1.1 9.7 2.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 PXF46321.1 - 0.22 11.1 7.3 0.33 10.5 7.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.9 PXF46321.1 - 0.29 11.4 8.0 0.43 10.9 8.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DHR10 PF18595.1 PXF46321.1 - 0.32 11.1 18.4 0.76 9.8 9.4 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 PXF46321.1 - 0.38 11.2 3.7 2.1 8.9 2.2 2.6 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein GvpL_GvpF PF06386.11 PXF46321.1 - 0.46 10.4 8.0 0.73 9.7 8.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF RmuC PF02646.16 PXF46321.1 - 0.51 9.4 9.0 0.35 10.0 2.0 2.2 1 1 1 2 2 2 0 RmuC family DUF5082 PF16888.5 PXF46321.1 - 0.61 10.4 11.0 6.2 7.1 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Jnk-SapK_ap_N PF09744.9 PXF46321.1 - 0.66 10.2 16.3 1 9.5 16.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FapA PF03961.13 PXF46321.1 - 0.66 8.5 6.6 1.1 7.8 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 PXF46321.1 - 0.67 10.7 7.8 0.71 10.6 6.2 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 PXF46321.1 - 0.79 7.6 4.6 1.2 7.0 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HIP1_clath_bdg PF16515.5 PXF46321.1 - 0.81 10.3 18.0 0.7 10.5 16.6 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 PXF46321.1 - 0.89 9.8 16.3 0.7 10.1 2.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 PXF46321.1 - 0.91 9.5 18.0 0.74 9.8 11.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 PXF46321.1 - 1.1 9.1 11.1 2.1 8.2 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 PXF46321.1 - 1.1 9.3 8.9 11 6.1 8.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LMP PF04778.12 PXF46321.1 - 1.4 8.8 9.8 0.94 9.4 6.2 2.0 1 1 0 2 2 2 0 LMP repeated region TFR_dimer PF04253.15 PXF46321.1 - 1.4 9.0 7.9 3.8 7.6 0.8 2.2 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain G_path_suppress PF15991.5 PXF46321.1 - 1.5 8.9 14.3 2.3 8.3 14.3 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Fungal_TACC PF12709.7 PXF46321.1 - 1.7 9.1 10.7 14 6.2 3.0 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins FlaC_arch PF05377.11 PXF46321.1 - 1.8 9.0 7.3 5.4 7.5 1.7 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 PXF46321.1 - 3.1 8.7 17.6 0.16 12.9 0.8 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 PXF46321.1 - 4.4 7.2 15.6 1.1 9.1 3.1 3.1 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 PXF46321.1 - 5.2 7.6 19.4 0.57 10.7 2.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF2070 PF09843.9 PXF46321.1 - 5.4 5.2 10.6 8.7 4.5 10.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF948 PF06103.11 PXF46321.1 - 5.5 7.3 5.5 70 3.8 4.1 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 PXF46321.1 - 6 7.0 16.0 5.6 7.1 14.5 1.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4337 PF14235.6 PXF46321.1 - 8.5 6.5 16.6 1.7 8.7 3.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) KLRAQ PF10205.9 PXF46321.1 - 8.6 6.7 13.4 1.4 9.2 1.3 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein APG6_N PF17675.1 PXF46321.1 - 9.1 6.8 24.0 4.7 7.7 12.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 PXF46321.1 - 9.9 6.2 17.5 1.2e+02 2.7 17.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1995 PF09353.10 PXF46322.1 - 2.1e-46 158.4 0.0 2.7e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Med25_SD1 PF11235.8 PXF46322.1 - 0.15 12.3 4.0 0.3 11.4 4.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Sec23_trunk PF04811.15 PXF46323.1 - 2.5e-16 60.0 0.0 3.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PXF46323.1 - 3.9e-11 42.7 0.0 1.2e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PXF46323.1 - 4.9e-07 29.7 7.1 8.8e-07 28.9 7.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PXF46323.1 - 0.026 15.3 0.0 0.053 14.3 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 PXF46323.1 - 0.08 12.4 0.2 0.08 12.4 0.2 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain AAA_25 PF13481.6 PXF46324.1 - 0.00095 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.11 PXF46324.1 - 0.0012 18.2 0.0 0.006 15.9 0.0 2.1 1 1 0 1 1 1 1 Rad51 CbiA PF01656.23 PXF46324.1 - 0.037 14.1 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ROK PF00480.20 PXF46325.1 - 3.6e-40 138.3 0.0 4.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 PXF46325.1 - 0.012 14.7 0.2 0.042 12.8 0.2 1.9 1 1 0 1 1 1 0 Glucokinase CBS PF00571.28 PXF46325.1 - 0.13 12.7 0.2 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 CBS domain PMM PF03332.13 PXF46326.1 - 4e-105 350.5 0.7 4.6e-105 350.3 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PXF46326.1 - 7.8e-06 25.8 0.0 0.00026 20.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF46326.1 - 1.3e-05 24.9 0.0 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase RabGAP-TBC PF00566.18 PXF46327.1 - 1.5e-38 132.6 1.3 1.1e-37 129.8 1.3 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Na_H_Exchanger PF00999.21 PXF46328.1 - 1.1e-35 123.2 34.6 1.3e-35 122.9 34.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_7 PF03441.14 PXF46329.1 - 5.6e-74 248.0 3.2 7.5e-74 247.6 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PXF46329.1 - 9.9e-37 126.5 0.0 2.7e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase bZIP_2 PF07716.15 PXF46330.1 - 0.0026 17.8 12.9 0.0026 17.8 12.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF46330.1 - 0.0066 16.5 11.9 0.0066 16.5 11.9 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 PXF46330.1 - 0.41 11.2 13.3 1 9.9 13.1 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor HrcA PF01628.21 PXF46330.1 - 0.64 9.9 4.7 1 9.2 3.1 1.9 2 0 0 2 2 2 0 HrcA protein C terminal domain LMBR1 PF04791.16 PXF46330.1 - 0.9 8.4 2.5 1.1 8.0 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UCH PF00443.29 PXF46331.1 - 4.5e-40 137.8 0.0 6.9e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 PXF46331.1 - 2.2e-21 75.4 0.0 7.7e-21 73.6 0.0 2.0 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 PXF46331.1 - 7e-19 67.4 0.0 1e-09 38.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 PXF46331.1 - 4.3e-10 39.8 0.0 1.2e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PXF46331.1 - 1.3e-08 34.8 0.0 1.9e-06 27.7 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SNase PF00565.17 PXF46332.1 - 1e-18 67.8 0.4 2.2e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Staphylococcal nuclease homologue ATP-synt_10 PF05176.14 PXF46333.1 - 1.4e-15 57.2 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF4596 PF15363.6 PXF46333.1 - 0.22 11.8 1.9 0.52 10.6 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) NUMOD3 PF07460.11 PXF46334.1 - 8e-11 42.0 3.4 1.7e-05 24.9 0.0 4.4 2 1 2 4 4 4 3 NUMOD3 motif (2 copies) Drc1-Sld2 PF11719.8 PXF46334.1 - 6.6e-08 32.5 0.0 0.0082 15.7 0.0 2.6 2 0 0 2 2 2 2 DNA replication and checkpoint protein Orn_Arg_deC_N PF02784.16 PXF46336.1 - 6.5e-49 166.5 0.0 8e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PXF46336.1 - 1.9e-21 76.1 0.0 2.6e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 PXF46336.1 - 7.1e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF5410 PF17422.2 PXF46336.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5410) EMC1_C PF07774.13 PXF46337.1 - 7.3e-38 130.4 0.0 1.3e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 PXF46337.1 - 0.0037 16.9 0.4 0.04 13.5 0.0 2.4 2 1 1 3 3 3 1 PQQ-like domain Apt1 PF10351.9 PXF46338.1 - 1.1e-35 123.4 0.2 6.3e-35 120.9 0.2 2.1 1 1 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 PXF46338.1 - 2.4e-11 44.0 0.0 5.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 PXF46338.1 - 0.015 15.3 0.1 0.049 13.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Not1 PF04054.15 PXF46339.1 - 1.4e-109 366.4 0.1 2.5e-109 365.6 0.1 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 PXF46339.1 - 2.4e-76 256.0 0.9 6.8e-76 254.6 0.9 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PXF46339.1 - 1.2e-48 164.8 3.4 2.9e-48 163.5 0.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 PXF46339.1 - 2e-48 164.1 0.0 5.3e-48 162.7 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 PXF46339.1 - 1.5e-17 64.0 0.4 4.4e-17 62.6 0.4 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PMT PF02366.18 PXF46340.1 - 3.8e-43 147.8 11.5 3.8e-43 147.8 11.5 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PXF46340.1 - 5.6e-40 137.1 17.5 1.6e-39 135.6 17.5 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase zf-C2H2_4 PF13894.6 PXF46341.1 - 7.4e-17 60.6 19.3 0.00038 21.0 0.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF46341.1 - 1.6e-16 59.9 22.0 7.5e-05 23.0 0.8 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 PXF46341.1 - 2.2e-16 59.3 22.5 0.00044 20.5 0.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type GAGA PF09237.11 PXF46341.1 - 6.6e-07 29.0 7.8 0.0097 15.7 0.5 4.1 1 1 3 4 4 4 3 GAGA factor zf-C2H2_6 PF13912.6 PXF46341.1 - 5.3e-06 26.3 23.3 0.13 12.3 1.6 4.8 4 1 0 4 4 4 3 C2H2-type zinc finger zf-trcl PF13451.6 PXF46341.1 - 2e-05 24.4 6.7 3.8e-05 23.5 1.1 2.8 3 0 0 3 3 3 1 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 PXF46341.1 - 2.7e-05 23.8 16.3 0.042 13.6 0.1 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-met PF12874.7 PXF46341.1 - 0.00017 21.8 12.9 2.6 8.5 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PXF46341.1 - 0.00018 21.7 10.4 0.056 13.7 0.9 3.2 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 PXF46341.1 - 0.00029 20.9 7.0 0.0074 16.4 0.3 3.3 1 1 2 3 3 3 1 Zinc ribbon domain zf-C2H2_3rep PF18868.1 PXF46341.1 - 0.00037 21.2 11.8 0.19 12.4 0.9 4.0 2 1 2 4 4 4 3 Zinc finger C2H2-type, 3 repeats zf-nanos PF05741.13 PXF46341.1 - 0.00088 19.4 13.1 0.28 11.5 0.3 4.3 3 1 1 4 4 4 2 Nanos RNA binding domain zf_UBZ PF18439.1 PXF46341.1 - 0.0018 17.8 8.1 8.2 6.1 0.1 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 PXF46341.1 - 0.011 16.1 12.9 2.4 8.5 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.6 PXF46341.1 - 0.013 15.4 7.0 18 5.4 0.0 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DZR PF12773.7 PXF46341.1 - 0.037 14.1 13.5 0.31 11.1 4.6 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.6 PXF46341.1 - 0.039 13.9 17.6 0.27 11.2 0.1 4.8 5 0 0 5 5 4 0 zinc-finger of a C2HC-type BolA PF01722.18 PXF46341.1 - 0.044 14.1 0.3 0.38 11.1 0.1 2.5 2 1 0 2 2 2 0 BolA-like protein Ta0938 PF11494.8 PXF46341.1 - 0.085 13.1 1.0 1.1 9.6 0.0 2.3 1 1 1 2 2 2 0 Ta0938 DUF2944 PF11161.8 PXF46341.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) FYDLN_acid PF09538.10 PXF46341.1 - 0.088 13.5 3.8 2.4 8.9 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_8 PF15909.5 PXF46341.1 - 0.14 12.5 10.6 0.99 9.8 2.4 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon ADK_lid PF05191.14 PXF46341.1 - 0.28 11.2 10.4 15 5.7 0.2 3.4 1 1 2 3 3 3 0 Adenylate kinase, active site lid Desulfoferrod_N PF06397.12 PXF46341.1 - 0.61 9.8 9.1 0.84 9.3 0.1 3.6 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_9 PF16293.5 PXF46341.1 - 0.63 9.9 6.3 2 8.3 0.3 3.0 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) zf-AN1 PF01428.16 PXF46341.1 - 0.85 9.8 18.3 9.7 6.5 0.3 4.6 2 2 2 4 4 4 0 AN1-like Zinc finger RecR PF02132.15 PXF46341.1 - 1 9.0 5.8 43 3.8 0.1 3.8 4 0 0 4 4 4 0 RecR protein ZZ PF00569.17 PXF46341.1 - 1.1 9.2 7.3 9.1 6.2 0.0 3.8 4 0 0 4 4 4 0 Zinc finger, ZZ type zinc_ribbon_4 PF13717.6 PXF46341.1 - 1.2 9.1 9.9 14 5.7 0.5 4.0 3 1 1 4 4 4 0 zinc-ribbon domain YacG PF03884.14 PXF46341.1 - 2.5 7.9 6.3 1.1 9.1 1.6 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Ogr_Delta PF04606.12 PXF46341.1 - 3.7 7.6 9.6 7.1 6.7 0.0 3.4 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_2 PF12756.7 PXF46341.1 - 3.9 7.9 13.5 12 6.3 1.4 3.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RRN7 PF11781.8 PXF46341.1 - 4.5 7.0 11.2 29 4.4 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 BST2 PF16716.5 PXF46342.1 - 0.027 15.1 1.7 0.06 13.9 0.2 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 PXF46342.1 - 0.22 12.2 0.9 0.39 11.4 0.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 PXF46342.1 - 0.37 9.3 7.8 0.43 9.1 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0184 PF03670.13 PXF46342.1 - 8.6 6.8 7.2 8 6.9 1.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Exo_endo_phos PF03372.23 PXF46343.1 - 1.2e-12 47.8 0.1 2e-12 47.1 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_Me_trans PF03054.16 PXF46345.1 - 5.4e-84 282.0 0.0 6.3e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 PXF46345.1 - 0.021 13.9 0.0 0.91 8.6 0.0 2.2 2 0 0 2 2 2 0 NAD synthase Asn_synthase PF00733.21 PXF46345.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Nbas_N PF15492.6 PXF46345.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal RHD3 PF05879.12 PXF46347.1 - 7.5e-33 113.7 0.1 9.2e-33 113.4 0.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) CbtA_toxin PF06755.12 PXF46347.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Pkinase PF00069.25 PXF46348.1 - 1.4e-66 224.5 0.0 1.9e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46348.1 - 3.1e-34 118.4 0.0 4.3e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF46348.1 - 0.00022 20.1 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF46348.1 - 0.0003 20.8 0.5 0.14 12.1 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF46348.1 - 0.002 17.5 0.0 0.01 15.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF46348.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 PXF46348.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DER1 PF04511.15 PXF46349.1 - 1.4e-38 132.8 9.9 1.6e-38 132.6 9.9 1.1 1 0 0 1 1 1 1 Der1-like family SMC_Nse1 PF07574.13 PXF46350.1 - 1.5e-09 38.0 3.2 1.1e-06 28.7 0.2 2.5 2 1 1 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex zf-RING_2 PF13639.6 PXF46351.1 - 3.1e-10 40.2 8.4 8.4e-10 38.8 8.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PXF46351.1 - 3.9e-09 36.2 7.0 9.2e-09 35.0 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF46351.1 - 8.7e-09 35.0 1.6 2e-08 33.8 1.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF46351.1 - 1e-06 28.4 6.6 1e-06 28.4 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF46351.1 - 2.2e-05 24.4 2.9 8.3e-05 22.5 2.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF46351.1 - 0.00051 20.3 11.4 0.001 19.3 9.9 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF46351.1 - 0.0098 15.9 7.7 0.038 14.1 7.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PXF46351.1 - 0.015 15.5 6.7 0.032 14.4 5.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PXF46351.1 - 0.031 14.2 7.9 0.056 13.4 7.0 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PXF46351.1 - 0.081 12.6 5.3 0.18 11.4 5.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PXF46351.1 - 0.1 12.8 9.3 1.6 9.0 9.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 PXF46351.1 - 0.17 11.8 6.8 3.9 7.5 7.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 PXF46351.1 - 7.4 7.0 10.8 20 5.6 10.4 2.0 1 1 1 2 2 2 0 RING-like domain LOR PF04525.12 PXF46352.1 - 9e-15 54.7 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related HCO3_cotransp PF00955.21 PXF46353.1 - 7.3e-142 473.8 16.1 3.1e-85 286.9 3.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.13 PXF46353.1 - 0.00094 19.1 0.1 0.092 12.5 0.0 2.2 2 0 0 2 2 2 2 Band 3 cytoplasmic domain IlvGEDA_leader PF08046.11 PXF46353.1 - 0.82 9.2 3.7 3.5 7.2 3.7 2.1 1 0 0 1 1 1 0 IlvGEDA operon leader peptide MFS_MOT1 PF16983.5 PXF46353.1 - 1.4 9.4 11.6 4.3 7.8 0.1 4.1 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily DUF962 PF06127.11 PXF46353.1 - 2.4 8.3 5.9 2 8.6 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF962) SOUL PF04832.12 PXF46354.1 - 5.2e-36 124.3 0.0 8.3e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein Tcf25 PF04910.14 PXF46355.1 - 6.2e-62 209.7 0.0 9.2e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_8 PF13181.6 PXF46355.1 - 0.0071 16.5 0.0 0.052 13.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46355.1 - 0.01 15.8 0.2 0.01 15.8 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46355.1 - 0.11 12.4 0.1 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 PXF46355.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 PXF46355.1 - 0.55 10.5 2.7 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF46355.1 - 0.66 10.7 5.9 0.84 10.4 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP-alpha_N PF04086.13 PXF46355.1 - 1.2 9.0 15.2 2.5 7.9 15.2 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TPR_14 PF13428.6 PXF46355.1 - 5.4 8.1 7.4 6.4 7.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF46355.1 - 9.7 6.6 7.8 5.3 7.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 PXF46356.1 - 4.3e-16 59.2 17.3 6.3e-14 52.1 0.1 5.0 5 2 0 5 5 5 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 PXF46356.1 - 7.6e-07 29.3 16.4 7.8e-05 22.9 0.3 6.4 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 PXF46356.1 - 0.00014 22.2 0.4 0.98 10.2 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF46356.1 - 0.00061 20.3 14.1 3.2 8.3 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46356.1 - 0.0097 16.0 14.5 9.5 6.6 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 PXF46356.1 - 0.017 15.0 1.2 19 5.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF46356.1 - 0.049 13.8 5.8 0.33 11.2 0.6 4.8 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PXF46356.1 - 0.19 11.6 7.7 20 5.2 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46356.1 - 0.2 11.9 14.2 6.9 7.2 0.0 7.3 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46356.1 - 1.1 10.3 19.3 58 4.9 0.0 8.2 11 0 0 11 11 11 0 Tetratricopeptide repeat FANCI_S4 PF14678.6 PXF46357.1 - 1e-30 106.7 0.0 4.4e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 FANCI solenoid 4 FANCI_S2 PF14676.6 PXF46357.1 - 6e-26 91.7 6.6 1.3e-25 90.6 1.0 3.4 2 1 1 3 3 3 1 FANCI solenoid 2 FANCI_S1 PF14675.6 PXF46357.1 - 7.2e-18 65.0 0.4 2.1e-17 63.5 0.4 1.8 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 PXF46357.1 - 0.0033 17.4 0.1 0.0091 15.9 0.1 1.8 1 0 0 1 1 1 1 FANCI helical domain 1 DUF4327 PF14217.6 PXF46357.1 - 0.027 14.6 0.0 0.099 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) GPR_Gpa2_C PF11970.8 PXF46358.1 - 0.021 14.9 0.1 0.061 13.4 0.2 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Bap31 PF05529.12 PXF46359.1 - 5.8e-18 65.0 4.9 4.4e-16 59.0 4.9 2.1 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region LURAP PF14854.6 PXF46359.1 - 0.024 14.6 0.3 0.059 13.3 0.2 1.7 1 1 1 2 2 2 0 Leucine rich adaptor protein CitMHS PF03600.16 PXF46359.1 - 0.042 13.1 0.1 0.076 12.2 0.1 1.4 1 1 0 1 1 1 0 Citrate transporter HILPDA PF15220.6 PXF46359.1 - 0.3 11.2 2.6 1.7 8.8 0.5 2.4 1 1 1 2 2 2 0 Hypoxia-inducible lipid droplet-associated Methyltransf_31 PF13847.6 PXF46362.1 - 5.8e-12 45.7 0.0 1.8e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 PXF46362.1 - 5.3e-10 38.8 0.5 2.3e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 PXF46362.1 - 6.6e-10 39.6 0.2 1.1e-08 35.6 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 PXF46362.1 - 6.3e-07 29.1 0.1 9.9e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 PXF46362.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 PXF46362.1 - 1.4e-05 24.7 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 PXF46362.1 - 7.1e-05 22.5 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 PXF46362.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF46362.1 - 0.00033 21.2 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 PXF46362.1 - 0.00077 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N6_N4_Mtase PF01555.18 PXF46362.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 PXF46362.1 - 0.0029 17.3 0.8 0.13 11.9 0.8 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 PXF46362.1 - 0.0036 18.0 0.0 0.01 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PXF46362.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 PXF46362.1 - 0.039 14.0 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PXF46362.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MethyltransfD12 PF02086.15 PXF46362.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltrans_SAM PF10672.9 PXF46362.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase FtsJ PF01728.19 PXF46362.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GST_N_3 PF13417.6 PXF46364.1 - 6.4e-08 32.9 0.0 4.8e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PXF46364.1 - 4e-07 30.3 0.0 7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF46364.1 - 2.6e-06 27.6 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CCT PF06203.14 PXF46365.1 - 7.2e-10 38.8 7.7 7.2e-10 38.8 7.7 1.7 2 0 0 2 2 2 1 CCT motif Sporozoite_P67 PF05642.11 PXF46365.1 - 0.01 14.0 5.5 0.016 13.4 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MRP-S28 PF10213.9 PXF46366.1 - 7.1e-11 42.6 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AbiEi_3 PF11459.8 PXF46366.1 - 0.065 12.9 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system eIF3_p135 PF12807.7 PXF46366.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Pkinase_Tyr PF07714.17 PXF46368.1 - 3.4e-10 39.7 0.0 8.2e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF46368.1 - 6.8e-09 35.5 0.0 3e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF913 PF06025.12 PXF46368.1 - 0.18 10.8 1.6 0.37 9.7 0.0 2.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Pkinase PF00069.25 PXF46369.1 - 1.3e-37 129.6 0.0 3.5e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46369.1 - 1.7e-36 125.9 0.0 3.2e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase YL1 PF05764.13 PXF46369.1 - 0.015 15.4 6.5 0.036 14.2 6.5 1.6 1 0 0 1 1 1 0 YL1 nuclear protein MMS19_N PF14500.6 PXF46369.1 - 0.018 14.6 0.0 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DnaJ-X PF14308.6 PXF46370.1 - 8.3e-26 90.7 0.0 4.6e-25 88.3 0.0 2.1 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PXF46370.1 - 1.6e-25 89.0 2.8 1.6e-25 89.0 2.8 2.3 2 0 0 2 2 2 1 DnaJ domain Stathmin PF00836.19 PXF46370.1 - 0.03 14.3 2.0 0.079 12.9 2.0 1.6 1 0 0 1 1 1 0 Stathmin family SUZ PF12752.7 PXF46370.1 - 0.038 14.7 2.9 0.1 13.4 2.9 1.7 1 0 0 1 1 1 0 SUZ domain CENP-S PF15630.6 PXF46370.1 - 0.039 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 CENP-S protein CAP59_mtransfer PF11735.8 PXF46370.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Peptidase_C12 PF01088.21 PXF46371.1 - 8.9e-16 58.3 0.0 8.9e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2973 PF11189.8 PXF46371.1 - 0.0068 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2973) RNA_pol_3_Rpc31 PF11705.8 PXF46371.1 - 0.036 14.3 10.4 0.069 13.4 10.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 PXF46371.1 - 0.039 14.5 7.1 0.34 11.5 8.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Syntaxin-18_N PF10496.9 PXF46371.1 - 0.063 13.5 0.5 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus MPM1 PF17234.2 PXF46371.1 - 0.074 13.3 2.0 0.14 12.4 2.0 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 NOA36 PF06524.12 PXF46371.1 - 0.086 12.1 11.5 0.13 11.5 11.5 1.3 1 0 0 1 1 1 0 NOA36 protein UCH_C PF18031.1 PXF46371.1 - 2.9 7.9 5.4 0.66 9.9 0.3 2.6 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases ADH_N PF08240.12 PXF46372.1 - 4.9e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF46372.1 - 0.0033 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_S13_N PF08069.12 PXF46372.1 - 0.05 13.6 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Pkinase PF00069.25 PXF46373.1 - 9.4e-75 251.4 0.0 1.2e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46373.1 - 5e-46 157.1 0.0 6.8e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF46373.1 - 1.1e-07 31.4 0.0 8.7e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF46373.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PXF46373.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PXF46373.1 - 0.036 12.9 0.0 0.07 11.9 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 PXF46373.1 - 0.048 13.6 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 PXF46373.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Gp_dh_C PF02800.20 PXF46374.1 - 4e-70 234.5 0.0 5.4e-70 234.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PXF46374.1 - 4.3e-38 129.7 0.0 1.2e-37 128.2 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 PXF46374.1 - 0.023 14.8 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 PXF46375.1 - 6.2e-57 191.8 0.0 8.8e-57 191.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PXF46375.1 - 2.6e-25 88.6 0.0 3.5e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PXF46375.1 - 0.00025 21.2 0.1 0.00072 19.7 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PXF46375.1 - 0.00045 20.3 0.0 0.00094 19.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PXF46375.1 - 0.0086 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyridox_oxase_2 PF12766.7 PXF46376.1 - 9.6e-24 83.9 0.0 1.5e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PXF46376.1 - 0.00029 21.0 0.0 0.00056 20.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_6 PF13516.6 PXF46377.1 - 7.5e-08 31.8 1.2 5.1 7.4 0.0 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 PXF46377.1 - 4.2e-05 23.8 1.9 0.083 13.4 0.0 4.4 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PXF46377.1 - 0.00068 19.5 1.2 0.0016 18.3 1.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PXF46377.1 - 0.00085 19.0 0.1 1.6 8.6 0.0 3.7 3 0 0 3 3 3 2 Leucine rich repeat F-box PF00646.33 PXF46377.1 - 0.0084 16.0 1.5 0.026 14.4 1.5 1.9 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 PXF46377.1 - 0.0086 15.8 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1699) F-box-like_2 PF13013.6 PXF46377.1 - 0.13 12.3 0.1 0.42 10.6 0.0 2.0 2 1 0 2 2 2 0 F-box-like domain LRR_1 PF00560.33 PXF46377.1 - 0.37 11.5 0.1 0.37 11.5 0.1 6.0 9 0 0 9 9 9 0 Leucine Rich Repeat Mcl1_mid PF12341.8 PXF46378.1 - 2.1e-64 217.7 0.1 1.3e-62 211.8 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 PXF46378.1 - 2.6e-13 50.2 2.3 0.11 13.4 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46378.1 - 2.1e-08 34.4 0.0 0.0007 19.8 0.1 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF46378.1 - 0.0026 17.7 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PXF46378.1 - 0.0031 17.4 0.8 1.6 8.8 0.0 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 PXF46378.1 - 0.031 13.2 0.1 0.71 8.8 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rhodanese PF00581.20 PXF46379.1 - 1.1e-19 71.0 0.2 2e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain SLAIN PF15301.6 PXF46379.1 - 0.03 13.6 0.7 0.044 13.0 0.7 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family FA_desaturase PF00487.24 PXF46380.1 - 1.1e-18 68.0 27.3 1.1e-18 68.0 27.3 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 PXF46380.1 - 3.5e-12 46.3 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BPL_N PF09825.9 PXF46380.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal RAD51_interact PF15696.5 PXF46381.1 - 0.039 14.0 3.7 0.039 14.0 3.7 3.1 3 0 0 3 3 3 0 RAD51 interacting motif SAM_2 PF07647.17 PXF46382.1 - 6.8e-12 45.3 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PXF46382.1 - 7.7e-12 45.5 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF202 PF02656.15 PXF46382.1 - 2.5e-11 43.8 1.6 2.5e-11 43.8 1.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SAM_3 PF18016.1 PXF46382.1 - 0.001 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Vma12 PF11712.8 PXF46382.1 - 0.04 14.0 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CRPA PF05745.11 PXF46382.1 - 0.4 10.7 5.1 0.3 11.1 2.5 1.9 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PGAP1 PF07819.13 PXF46383.1 - 0.052 13.3 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein YnfE PF17452.2 PXF46383.1 - 0.1 12.9 0.5 0.25 11.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized YnfE-like SYF2 PF08231.12 PXF46384.1 - 6.9e-17 62.3 8.6 1.4e-16 61.3 8.6 1.7 1 1 0 1 1 1 1 SYF2 splicing factor Lipase_3 PF01764.25 PXF46385.1 - 2.5e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PXF46385.1 - 0.0029 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF46385.1 - 0.0094 16.6 0.1 0.018 15.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PXF46386.1 - 1.2e-61 208.3 0.0 1.5e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PXF46386.1 - 3.7e-08 34.2 0.5 4.7e-08 33.9 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF46386.1 - 4.4e-08 32.7 0.3 0.0028 17.0 0.1 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF46386.1 - 1.1e-07 31.8 0.4 1.3e-06 28.2 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 PXF46386.1 - 3.6e-06 26.7 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PXF46386.1 - 0.00021 21.2 0.1 0.00057 19.8 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 PXF46386.1 - 0.00026 20.7 0.0 0.00047 19.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 PXF46386.1 - 0.0034 17.0 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 PXF46386.1 - 0.0056 15.4 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Cutinase PF01083.22 PXF46386.1 - 0.0064 16.5 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 PXF46386.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 PXF46386.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PXF46386.1 - 0.017 14.6 0.5 4.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family PE-PPE PF08237.11 PXF46386.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.20 PXF46386.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 PXF46386.1 - 0.035 13.9 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Esterase PF00756.20 PXF46386.1 - 0.077 12.6 0.1 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DUF2920 PF11144.8 PXF46386.1 - 0.21 10.7 0.0 1.2 8.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Sulfotransfer_2 PF03567.14 PXF46387.1 - 1.3e-05 25.3 1.2 1.3e-05 25.3 1.2 1.9 2 1 0 2 2 2 1 Sulfotransferase family Macoilin PF09726.9 PXF46387.1 - 8.2 4.8 20.5 11 4.4 20.5 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_L29 PF00831.23 PXF46388.1 - 5.2e-19 68.0 1.0 5.2e-19 68.0 1.0 2.3 2 1 1 3 3 3 1 Ribosomal L29 protein Aminotran_1_2 PF00155.21 PXF46389.1 - 3.2e-49 168.0 0.0 4e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 PXF46389.1 - 0.00029 19.7 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 PXF46389.1 - 0.00094 17.8 0.0 0.0015 17.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PXF46389.1 - 0.0066 15.4 0.2 0.017 14.1 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PXF46389.1 - 0.0077 15.6 0.3 0.012 15.0 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4131 PF13567.6 PXF46390.1 - 0.02 14.6 3.7 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 PXF46390.1 - 0.026 14.5 13.4 0.15 12.1 2.9 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PDZ_3 PF17815.1 PXF46390.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Ni_hydr_CYTB PF01292.20 PXF46390.1 - 0.04 13.5 2.0 0.39 10.3 2.0 2.2 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PTPS_related PF10131.9 PXF46390.1 - 0.23 9.8 4.0 0.41 8.9 4.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein CDP-OH_P_transf PF01066.21 PXF46390.1 - 0.53 11.1 4.8 6.7 7.6 0.1 2.3 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase DUF2207 PF09972.9 PXF46390.1 - 0.68 8.6 10.3 0.14 10.9 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ABC2_membrane PF01061.24 PXF46390.1 - 0.9 8.9 13.9 0.1 12.0 0.8 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF2371 PF10177.9 PXF46390.1 - 2 8.6 3.6 1.8 8.7 0.2 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF4658 PF15555.6 PXF46390.1 - 5.1 7.2 6.3 3.3 7.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) CPBP PF02517.16 PXF46390.1 - 5.7 7.4 9.3 0.42 11.0 1.1 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease DnaJ PF00226.31 PXF46392.1 - 4.1e-24 84.5 2.6 8.8e-24 83.4 2.6 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 PXF46392.1 - 1.2e-22 80.5 0.3 1.2e-22 80.5 0.3 2.7 3 0 0 3 3 3 1 X-domain of DnaJ-containing TPR_14 PF13428.6 PXF46392.1 - 0.00012 22.5 16.0 0.02 15.7 2.9 4.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46392.1 - 0.00068 19.3 0.1 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 PXF46392.1 - 0.0016 18.4 5.5 0.034 14.3 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46392.1 - 0.005 16.6 0.4 13 5.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF46392.1 - 0.032 14.4 21.3 0.81 9.9 6.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF46392.1 - 0.061 13.8 15.5 1 9.9 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46392.1 - 0.12 12.6 0.0 48 4.5 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 PXF46392.1 - 0.19 10.7 0.7 2 7.4 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Ufm1 PF03671.14 PXF46392.1 - 0.31 11.2 1.0 86 3.3 0.1 3.9 3 0 0 3 3 3 0 Ubiquitin fold modifier 1 protein SIS PF01380.22 PXF46393.1 - 5.6e-52 175.0 1.0 1.4e-26 92.9 0.3 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PXF46393.1 - 1.1e-14 54.8 0.0 2.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 PXF46393.1 - 1.3e-10 41.2 0.0 3.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PXF46393.1 - 4.8e-05 22.4 0.0 9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 PXF46393.1 - 0.00039 20.4 0.0 0.02 14.9 0.0 2.8 2 1 0 2 2 2 1 SIS domain CRCB PF02537.15 PXF46394.1 - 1.4e-27 95.8 12.5 9.6e-15 54.7 1.4 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CAML PF14963.6 PXF46395.1 - 0.021 15.0 1.5 0.73 9.9 0.1 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Sad1_UNC PF07738.13 PXF46397.1 - 7.7e-25 87.4 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ABA_GPCR PF12430.8 PXF46398.1 - 1.3e-23 83.7 9.3 1.3e-23 83.7 9.3 3.3 2 2 2 4 4 4 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 PXF46398.1 - 8.5e-14 51.4 0.2 8.5e-14 51.4 0.2 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF641 PF04859.12 PXF46398.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ABC2_membrane PF01061.24 PXF46399.1 - 8.1e-79 263.9 48.1 6.1e-41 140.2 10.1 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PXF46399.1 - 1.2e-29 103.6 0.1 9.5e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PXF46399.1 - 8.9e-11 41.5 34.5 1.8e-07 30.6 10.0 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PXF46399.1 - 0.00013 21.9 1.1 0.027 14.4 0.2 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PXF46399.1 - 0.00014 22.3 0.3 0.015 15.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PXF46399.1 - 0.00043 20.0 2.0 0.0053 16.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF46399.1 - 0.035 14.4 0.1 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Alba PF01918.21 PXF46399.1 - 0.045 13.6 0.1 4.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Alba AAA_25 PF13481.6 PXF46399.1 - 0.06 12.9 0.1 0.06 12.9 0.1 3.1 4 0 0 4 4 3 0 AAA domain DUF2399 PF09664.10 PXF46399.1 - 0.063 13.2 0.2 0.18 11.7 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function C-terminus (DUF2399) TIP49 PF06068.13 PXF46399.1 - 0.064 12.5 0.3 0.12 11.6 0.3 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain PDR_CDR PF06422.12 PXF46399.1 - 0.079 12.9 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 CDR ABC transporter AAA_33 PF13671.6 PXF46399.1 - 0.1 12.8 1.0 4.5 7.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 PXF46399.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PXF46399.1 - 0.16 12.5 0.3 0.37 11.3 0.3 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF46399.1 - 0.26 11.2 4.4 1.2 9.1 0.3 3.2 4 0 0 4 4 3 0 NACHT domain SLATT_4 PF18186.1 PXF46399.1 - 0.54 9.9 3.1 0.61 9.7 0.9 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 DLIC PF05783.11 PXF46399.1 - 0.81 8.4 3.1 2.5 6.9 0.4 2.5 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) COPI_C PF06957.11 PXF46399.1 - 5 5.8 6.6 9.8 4.8 6.6 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Kelch_6 PF13964.6 PXF46401.1 - 2.3e-21 75.3 1.2 0.00093 19.4 0.0 5.8 4 1 1 5 5 5 5 Kelch motif Malectin PF11721.8 PXF46401.1 - 5.6e-15 55.8 0.0 8.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Malectin domain Kelch_1 PF01344.25 PXF46401.1 - 1.8e-11 43.4 11.8 0.0028 17.2 0.3 6.2 5 2 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 PXF46401.1 - 9.1e-06 25.6 13.0 0.017 15.1 0.3 5.8 3 2 2 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF46401.1 - 1.5e-05 25.2 6.2 2.9 8.3 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PXF46401.1 - 0.00011 22.1 4.9 0.079 13.0 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 PXF46401.1 - 0.003 17.5 10.3 0.49 10.5 0.0 6.0 6 1 0 6 6 6 1 Kelch motif DUF4763 PF15960.5 PXF46402.1 - 0.0053 16.1 0.8 0.0064 15.8 0.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) bZIP_2 PF07716.15 PXF46402.1 - 0.009 16.1 1.7 0.43 10.7 0.2 2.3 2 0 0 2 2 2 2 Basic region leucine zipper OAS1_C PF10421.9 PXF46404.1 - 0.011 15.3 0.0 0.96 8.9 0.0 2.3 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus zf-C3HC4_3 PF13920.6 PXF46405.1 - 1.6e-12 47.0 5.6 2.3e-12 46.6 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF46405.1 - 1.9e-10 40.4 6.3 2.9e-10 39.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF46405.1 - 8e-09 35.7 9.6 1.2e-08 35.2 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF46405.1 - 2.1e-08 33.9 9.1 3.3e-08 33.2 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF46405.1 - 4.4e-08 33.0 6.3 6.7e-08 32.4 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PXF46405.1 - 4.9e-08 32.7 6.5 7.7e-08 32.1 6.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PXF46405.1 - 7.4e-08 32.3 4.5 7.4e-08 32.3 4.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PXF46405.1 - 1.7e-05 24.8 8.5 2.8e-05 24.2 8.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PXF46405.1 - 0.00019 21.7 5.3 0.00031 21.0 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF46405.1 - 0.0031 17.5 2.6 0.0048 16.9 2.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 PXF46405.1 - 0.005 16.8 1.3 0.0072 16.3 1.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 PXF46405.1 - 0.012 15.5 2.0 0.02 14.8 2.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 PXF46405.1 - 0.16 11.3 0.5 0.34 10.3 0.5 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_10 PF16685.5 PXF46405.1 - 0.23 11.6 5.3 0.36 11.0 5.3 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 PXF46405.1 - 0.33 11.1 4.3 1.7 8.8 4.3 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 PXF46405.1 - 2.4 8.0 8.4 6.1 6.7 8.2 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CPBP PF02517.16 PXF46406.1 - 2.7e-16 59.7 7.4 2.7e-16 59.7 7.4 3.2 2 2 0 2 2 2 1 CPBP intramembrane metalloprotease S1 PF00575.23 PXF46407.1 - 3.9e-19 68.8 0.1 2.1e-08 34.4 0.5 2.4 2 0 0 2 2 2 2 S1 RNA binding domain RNase_II_C_S1 PF18614.1 PXF46407.1 - 0.058 13.4 1.0 14 5.7 0.6 2.4 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain TAT_signal PF10518.9 PXF46408.1 - 0.00043 20.0 5.6 0.00087 19.0 5.6 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence PsbQ PF05757.11 PXF46408.1 - 0.029 14.1 3.9 0.074 12.8 3.9 1.6 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) UCR_Fe-S_N PF10399.9 PXF46408.1 - 0.088 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal XRN_N PF03159.18 PXF46409.1 - 1.9e-88 296.0 0.0 3.2e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PXF46409.1 - 4.9e-87 292.7 1.4 3.2e-60 204.4 0.8 2.2 1 1 1 2 2 2 2 Xrn1 helical domain SHMT PF00464.19 PXF46410.1 - 1.7e-199 662.5 0.0 1.9e-199 662.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 PXF46410.1 - 0.00059 18.9 0.1 0.00099 18.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PXF46410.1 - 0.048 12.9 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase NAD_Gly3P_dh_N PF01210.23 PXF46411.1 - 8.8e-49 165.5 0.0 1.3e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PXF46411.1 - 6.6e-42 143.1 0.3 1.2e-41 142.3 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DXPR_C PF13288.6 PXF46411.1 - 0.05 13.9 0.2 12 6.2 0.2 2.3 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain Ureidogly_lyase PF04115.12 PXF46411.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase Na_H_Exchanger PF00999.21 PXF46412.1 - 7.1e-64 216.0 52.3 9.6e-64 215.5 52.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 PXF46412.1 - 3.4e-27 95.0 0.1 9.7e-26 90.3 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain ERG4_ERG24 PF01222.17 PXF46412.1 - 0.058 12.2 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Cullin PF00888.22 PXF46413.1 - 2.4e-181 604.5 0.2 3e-181 604.2 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PXF46413.1 - 8.2e-25 86.6 0.5 2.4e-24 85.1 0.5 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain KCNQ_channel PF03520.14 PXF46413.1 - 0.098 12.5 0.8 0.25 11.2 0.4 1.9 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel Methyltransf_29 PF03141.16 PXF46414.1 - 8.5e-28 97.2 0.3 2.7e-22 79.0 0.1 2.3 1 1 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.12 PXF46414.1 - 4.3e-15 56.1 0.0 1.2e-10 41.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46414.1 - 2.1e-08 34.7 0.0 3.1e-05 24.6 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 PXF46414.1 - 8.2e-07 28.6 0.0 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PXF46414.1 - 4.8e-06 26.5 0.0 3.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF46414.1 - 1.8e-05 25.4 0.0 0.00074 20.2 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46414.1 - 0.00038 20.3 0.0 0.1 12.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_PK PF05891.12 PXF46414.1 - 0.0013 18.3 0.0 0.0099 15.4 0.0 2.3 2 1 0 2 2 2 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 PXF46415.1 - 7.9e-37 127.0 3.3 1.1e-36 126.6 3.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 PXF46415.1 - 3.8e-16 59.3 0.0 6.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF46415.1 - 9.9e-13 48.6 0.0 3.2e-12 46.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46415.1 - 2.8e-12 47.2 0.0 6.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF46415.1 - 3.7e-11 43.1 0.0 6.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF46415.1 - 7.4e-10 39.5 0.0 1.6e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF46415.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PXF46415.1 - 8e-06 25.4 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 PXF46415.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 PXF46415.1 - 0.00048 19.8 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 PXF46415.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 PXF46415.1 - 0.0069 15.4 0.3 0.033 13.2 0.3 1.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 PXF46415.1 - 0.0083 15.8 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) GidB PF02527.15 PXF46415.1 - 0.011 15.1 0.1 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 PXF46415.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 PXF46415.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 PXF46415.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 PXF46415.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 PXF46415.1 - 0.063 12.6 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain MetW PF07021.12 PXF46415.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW MIP PF00230.20 PXF46416.1 - 8.4e-27 94.4 23.7 8.7e-26 91.0 23.8 2.1 1 1 0 1 1 1 1 Major intrinsic protein C2 PF00168.30 PXF46417.1 - 3e-08 33.9 0.0 3.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain eIF-5a PF01287.20 PXF46417.1 - 0.22 11.7 1.8 2.6 8.2 1.2 2.8 2 1 1 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold zf-RING_2 PF13639.6 PXF46418.1 - 3.6e-14 52.8 5.5 5.3e-14 52.3 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF46418.1 - 1.8e-11 43.7 4.4 2.9e-11 43.0 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PXF46418.1 - 9.3e-10 38.1 3.0 1.6e-09 37.3 3.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PXF46418.1 - 2.6e-09 36.8 4.0 3.9e-09 36.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46418.1 - 8.5e-09 35.6 6.6 2.1e-08 34.3 6.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PXF46418.1 - 3.4e-08 33.4 1.8 5.7e-08 32.6 1.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF46418.1 - 1.1e-06 28.3 4.0 1.7e-06 27.8 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF46418.1 - 1.1e-05 25.3 4.7 1.6e-05 24.7 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PXF46418.1 - 0.00037 20.1 4.9 0.00058 19.4 4.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PXF46418.1 - 0.002 17.9 2.9 0.0034 17.1 2.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PXF46418.1 - 0.0023 18.0 4.3 0.0054 16.8 4.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PXF46418.1 - 0.0027 17.8 5.5 0.013 15.7 5.5 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 PXF46418.1 - 0.0082 16.0 5.1 0.015 15.1 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 PXF46418.1 - 0.02 14.3 0.3 0.025 14.0 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1272 PF06906.11 PXF46418.1 - 0.022 14.9 1.4 0.036 14.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 PXF46418.1 - 0.031 14.4 1.7 0.049 13.7 1.7 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING-like PF08746.11 PXF46418.1 - 0.039 14.3 6.3 0.069 13.5 6.3 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 PXF46418.1 - 0.062 13.4 3.7 0.13 12.4 3.7 1.5 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 PXF46418.1 - 0.083 12.8 4.7 0.15 11.9 4.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 PXF46418.1 - 0.14 12.4 4.1 0.51 10.5 4.1 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 PXF46418.1 - 0.44 10.5 6.3 2.4 8.2 6.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 PXF46418.1 - 0.76 9.9 4.8 1.9 8.6 4.8 1.8 1 1 0 1 1 1 0 Zinc-finger ABC1 PF03109.16 PXF46419.1 - 1e-22 80.6 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PXF46419.1 - 9.4e-05 22.4 0.3 0.00026 21.0 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PXF46419.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 PXF46419.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Ovate PF04844.13 PXF46419.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional repressor, ovate Fer2 PF00111.27 PXF46420.1 - 1.7e-08 34.3 2.8 1.7e-08 34.3 2.8 2.7 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 PXF46420.1 - 0.019 15.0 0.4 0.048 13.7 0.4 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain HD_3 PF13023.6 PXF46421.1 - 2.7e-42 144.5 0.2 3.3e-42 144.2 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 PXF46421.1 - 6.8e-10 39.0 0.1 1.1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 PXF46421.1 - 0.00053 20.2 0.2 0.00096 19.4 0.2 1.4 1 0 0 1 1 1 1 HD domain TolA_bind_tri PF16331.5 PXF46422.1 - 0.0045 17.0 0.5 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 TolA binding protein trimerisation GIT_CC PF16559.5 PXF46422.1 - 0.012 15.4 0.6 0.11 12.3 0.1 2.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UCH PF00443.29 PXF46423.1 - 1.8e-13 50.6 0.0 8.2e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF46423.1 - 2.6e-06 27.3 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TIM PF00121.18 PXF46424.1 - 4e-55 186.8 0.0 4.6e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF525 PF04379.14 PXF46425.1 - 1.7e-27 95.4 0.0 2.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 ApaG domain UVR PF02151.19 PXF46425.1 - 2.8e-08 33.2 10.5 8.3e-06 25.4 0.7 2.2 2 0 0 2 2 2 2 UvrB/uvrC motif BAR_2 PF10455.9 PXF46425.1 - 0.076 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Amidohydro_1 PF01979.20 PXF46426.1 - 3.1e-50 171.4 0.0 3.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PXF46426.1 - 1.1e-09 38.3 0.4 3.5e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 PXF46426.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Spc7 PF08317.11 PXF46427.1 - 0.082 11.8 21.4 0.017 14.0 13.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 PXF46427.1 - 0.32 11.3 14.1 0.16 12.3 7.6 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm UPF0242 PF06785.11 PXF46427.1 - 4.5 7.3 20.4 0.97 9.5 12.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 PXF46427.1 - 4.8 6.9 23.8 1.4 8.7 13.9 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 PXF46428.1 - 0.082 11.8 21.4 0.017 14.0 13.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Val_tRNA-synt_C PF10458.9 PXF46428.1 - 0.32 11.3 14.1 0.16 12.3 7.6 2.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm UPF0242 PF06785.11 PXF46428.1 - 4.5 7.3 20.4 0.97 9.5 12.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 PXF46428.1 - 4.8 6.9 23.8 1.4 8.7 13.9 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Peptidase_S49 PF01343.18 PXF46429.1 - 0.16 11.9 0.2 0.23 11.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N6_N4_Mtase PF01555.18 PXF46431.1 - 8.9e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 DNA methylase SET PF00856.28 PXF46431.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.6 2 0 0 2 2 2 1 SET domain Met_10 PF02475.16 PXF46431.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein T2SSK PF03934.13 PXF46431.1 - 0.21 10.9 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K RFX_DNA_binding PF02257.15 PXF46432.1 - 0.084 13.5 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain Enolase_C PF00113.22 PXF46433.1 - 4e-151 502.3 0.0 5.9e-151 501.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PXF46433.1 - 1.2e-56 190.5 0.2 4.2e-56 188.7 0.2 2.0 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PXF46433.1 - 3.6e-09 36.5 0.0 7.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PXF46433.1 - 9.8e-06 24.9 0.1 2.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus RdRP_5 PF07925.11 PXF46433.1 - 0.28 8.5 0.0 0.4 8.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Ras PF00071.22 PXF46434.1 - 2.6e-60 202.7 1.5 3.5e-60 202.3 1.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF46434.1 - 1.5e-31 109.1 0.5 2.9e-31 108.2 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF46434.1 - 1.2e-14 54.2 0.2 1.8e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PXF46434.1 - 0.0021 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PXF46434.1 - 0.0082 16.1 0.3 0.18 11.7 0.2 2.3 1 1 2 3 3 3 1 RsgA GTPase CENP-M PF11111.8 PXF46434.1 - 0.0083 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Centromere protein M (CENP-M) SRPRB PF09439.10 PXF46434.1 - 0.014 14.8 0.2 0.018 14.5 0.2 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PXF46434.1 - 0.041 13.2 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LANC_like PF05147.13 PXF46434.1 - 0.065 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Hus1 PF04005.12 PXF46435.1 - 2.3e-52 177.9 0.0 2.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.18 PXF46435.1 - 0.0099 15.6 0.1 0.044 13.5 0.0 2.0 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain Skp1 PF01466.19 PXF46436.1 - 3.5e-25 87.9 0.2 6.3e-25 87.0 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 PXF46436.1 - 1.2e-19 70.2 0.4 3e-19 68.9 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 PXF46436.1 - 0.015 15.5 0.1 0.028 14.7 0.1 1.4 1 1 0 1 1 1 0 BTB/POZ domain zf-primase PF09329.11 PXF46436.1 - 0.091 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Primase zinc finger MFS_1 PF07690.16 PXF46437.1 - 3.1e-25 88.8 17.9 3.1e-25 88.8 17.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RINGv PF12906.7 PXF46439.1 - 2.3e-15 56.4 6.4 4.2e-15 55.6 6.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PXF46439.1 - 0.03 14.6 6.8 0.064 13.6 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain HIG_1_N PF04588.13 PXF46439.1 - 0.044 14.0 1.5 7.8 6.8 0.1 3.2 2 0 0 2 2 2 0 Hypoxia induced protein conserved region HA PF03457.14 PXF46440.1 - 1e-56 189.1 14.5 2.6e-19 69.3 1.1 3.2 3 0 0 3 3 3 3 Helicase associated domain DUF3047 PF11249.8 PXF46440.1 - 0.64 9.4 10.6 0.18 11.3 1.5 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3047) UCH PF00443.29 PXF46442.1 - 6.3e-61 206.1 0.0 1.1e-60 205.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF46442.1 - 6.3e-33 114.7 3.8 3.9e-24 85.8 1.3 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PXF46442.1 - 0.014 14.9 6.8 0.091 12.2 2.1 3.4 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RHD3 PF05879.12 PXF46443.1 - 9.2e-161 536.6 0.0 8.6e-159 530.1 0.0 2.1 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 PXF46443.1 - 4.8e-05 22.8 0.0 8.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 PXF46443.1 - 0.00094 19.2 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF46443.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 PXF46443.1 - 0.0062 17.1 0.0 0.025 15.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 PXF46443.1 - 0.02 15.4 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PXF46443.1 - 0.023 14.5 0.0 0.091 12.5 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 PXF46443.1 - 0.023 15.0 0.1 0.45 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Transferase PF02458.15 PXF46444.1 - 0.043 12.5 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Transferase family Di19_C PF14571.6 PXF46445.1 - 0.071 13.6 3.7 0.08 13.5 3.7 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF3391 PF11871.8 PXF46445.1 - 0.2 12.2 6.8 0.22 12.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Casc1_N PF15927.5 PXF46445.1 - 0.37 10.4 16.6 0.41 10.3 16.6 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Connexin PF00029.19 PXF46445.1 - 0.69 9.6 6.3 0.77 9.5 6.3 1.0 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 PXF46445.1 - 2.2 8.3 5.0 2.3 8.3 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EnY2 PF10163.9 PXF46446.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 SlyX PF04102.12 PXF46449.1 - 0.012 16.2 0.8 0.012 16.2 0.8 2.1 3 0 0 3 3 3 0 SlyX Cyclin_N PF00134.23 PXF46450.1 - 5.1e-35 120.0 0.6 8.6e-35 119.3 0.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF46450.1 - 3e-16 59.6 0.3 6.7e-16 58.4 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cupin_1 PF00190.22 PXF46451.1 - 2.3e-17 63.0 0.2 3e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF46451.1 - 7.2e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cyclin_N PF00134.23 PXF46455.1 - 3.8e-35 120.4 1.0 6.5e-35 119.6 1.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF46455.1 - 2.5e-16 59.8 0.3 6.1e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cupin_1 PF00190.22 PXF46456.1 - 2.3e-17 63.0 0.2 3e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF46456.1 - 7.2e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 PXF46457.1 - 8.4e-15 54.7 0.2 1.1e-14 54.3 0.2 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PXF46457.1 - 2.6e-08 33.5 0.0 3.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cyclin_N PF00134.23 PXF46458.1 - 5.3e-35 119.9 0.8 8.9e-35 119.2 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF46458.1 - 2.6e-16 59.8 0.3 6.1e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M20 PF01546.28 PXF46460.1 - 2e-10 40.7 0.0 3.9e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 PXF46460.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Helicase_C PF00271.31 PXF46462.1 - 1.7e-11 44.4 0.0 3.7e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF1031 PF06275.11 PXF46462.1 - 0.096 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DEAD PF00270.29 PXF46463.1 - 1.3e-12 47.8 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase PheRS_DBD2 PF18554.1 PXF46466.1 - 0.17 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Dimer_Tnp_hAT PF05699.14 PXF46468.1 - 3.3e-06 26.8 0.7 5.6e-06 26.1 0.7 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HABP4_PAI-RBP1 PF04774.15 PXF46469.1 - 0.11 13.3 4.3 0.18 12.6 0.2 2.2 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Ribonuc_red_lgC PF02867.15 PXF46470.1 - 5.2e-185 615.9 0.0 1e-184 615.0 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PXF46470.1 - 1e-23 83.1 0.0 3e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PXF46470.1 - 1.8e-18 66.9 0.9 3.5e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 ATP cone domain RIBIOP_C PF04950.12 PXF46471.1 - 1.2e-96 323.6 0.0 1.2e-96 323.6 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PXF46471.1 - 1.7e-11 44.1 0.0 6.6e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain ELP6 PF09807.9 PXF46472.1 - 0.00012 21.6 0.1 0.00047 19.7 0.0 1.8 2 0 0 2 2 2 1 Elongation complex protein 6 CDC45 PF02724.14 PXF46473.1 - 0.072 11.4 38.8 0.11 10.8 38.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Dapper PF15268.6 PXF46473.1 - 0.61 8.9 52.5 0.63 8.8 52.5 1.1 1 0 0 1 1 1 0 Dapper Caldesmon PF02029.15 PXF46473.1 - 0.67 8.6 46.1 1.1 8.0 46.1 1.4 1 0 0 1 1 1 0 Caldesmon GREB1 PF15782.5 PXF46473.1 - 5.2 4.0 47.8 7.1 3.6 47.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4045 PF13254.6 PXF46473.1 - 6.8 6.2 44.9 12 5.4 44.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Agenet PF05641.12 PXF46474.1 - 0.059 13.9 0.3 0.12 12.8 0.3 1.6 1 0 0 1 1 1 0 Agenet domain DUF16 PF01519.16 PXF46475.1 - 0.0039 17.6 4.4 0.0044 17.5 2.9 1.7 1 1 1 2 2 2 1 Protein of unknown function DUF16 ACP_PD PF04336.12 PXF46475.1 - 0.0046 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase FapA PF03961.13 PXF46475.1 - 0.006 15.2 1.8 0.0074 14.9 1.8 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Com_YlbF PF06133.11 PXF46475.1 - 0.014 16.0 6.5 0.016 15.8 4.4 2.1 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Tup_N PF08581.10 PXF46475.1 - 0.02 15.2 4.2 0.37 11.1 1.8 2.8 1 1 1 2 2 2 0 Tup N-terminal WDCP PF15390.6 PXF46475.1 - 0.037 12.4 3.5 0.042 12.2 3.5 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Seryl_tRNA_N PF02403.22 PXF46475.1 - 0.16 12.2 7.6 0.12 12.6 5.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 PXF46475.1 - 0.29 11.4 2.2 19 5.6 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 PXF46475.1 - 0.39 9.9 6.3 0.17 11.1 3.9 1.5 1 1 1 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 PXF46475.1 - 0.49 10.5 7.4 0.45 10.6 4.4 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 PXF46475.1 - 3.3 7.9 6.4 1.7 8.8 2.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_S9 PF00326.21 PXF46476.1 - 9e-23 80.9 0.0 1.5e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 PXF46476.1 - 2.1e-08 33.9 1.8 0.025 14.5 0.1 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 PXF46476.1 - 0.00095 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 PXF46476.1 - 0.0074 15.6 0.1 0.19 11.0 0.2 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF46476.1 - 0.053 13.2 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mannosyl_trans3 PF11051.8 PXF46477.1 - 1.9e-08 34.0 0.0 5.9e-07 29.1 0.0 2.7 2 1 0 2 2 2 1 Mannosyltransferase putative zf-CDGSH PF09360.10 PXF46479.1 - 1e-09 38.4 0.6 1.5e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type PS_Dcarbxylase PF02666.15 PXF46480.1 - 1.3e-41 142.3 0.0 1.8e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 PXF46480.1 - 9.3e-32 109.9 0.0 1.6e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 PXF46480.1 - 0.19 11.6 0.6 0.57 10.1 0.3 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like Sds3 PF08598.11 PXF46481.1 - 1.7 8.6 12.9 5.1 7.0 12.9 1.9 1 1 0 1 1 1 0 Sds3-like CYTH PF01928.21 PXF46483.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 CYTH domain RRM_1 PF00076.22 PXF46485.1 - 3.3e-17 62.1 0.0 4.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PXF46485.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 PXF46485.1 - 0.12 12.6 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter UCR_hinge PF02320.16 PXF46486.1 - 1.7e-22 79.4 2.2 1.9e-22 79.2 2.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 PXF46486.1 - 0.00036 20.5 2.6 0.31 11.1 0.1 2.5 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 PXF46486.1 - 0.012 15.7 5.0 1.5 9.1 0.3 2.3 2 0 0 2 2 2 0 CHCH domain UPF0203 PF05254.12 PXF46486.1 - 0.048 13.9 5.6 0.47 10.7 1.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cullin_binding PF03556.15 PXF46487.1 - 1.3e-28 99.8 0.1 2.1e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Cullin binding WD40 PF00400.32 PXF46488.1 - 8.6e-65 213.1 15.9 1.6e-11 44.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46488.1 - 2.1e-26 92.0 0.2 1.3e-05 25.4 0.0 6.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF46488.1 - 1.1e-14 54.8 0.0 7.6e-07 29.2 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PXF46488.1 - 6.4e-10 38.8 0.0 0.00076 18.9 0.0 3.8 2 1 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 PXF46488.1 - 2e-09 36.7 1.8 0.19 10.3 0.1 4.9 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Frtz PF11768.8 PXF46488.1 - 2.7e-08 32.6 0.0 0.00019 19.9 0.0 3.0 2 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 PXF46488.1 - 9.1e-07 28.2 0.2 0.013 14.6 0.0 3.9 1 1 4 5 5 5 3 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 PXF46488.1 - 6.6e-05 22.0 0.4 2.3 7.1 0.0 3.7 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PXF46488.1 - 0.00017 20.3 0.5 0.03 12.9 0.0 3.2 1 1 0 3 3 3 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 PXF46488.1 - 0.0011 18.1 0.2 0.022 13.8 0.0 2.6 1 1 2 3 3 3 1 Coatomer WD associated region Serglycin PF04360.12 PXF46488.1 - 0.0014 18.6 0.1 0.0049 16.8 0.0 1.9 2 1 1 3 3 3 1 Serglycin PQQ PF01011.21 PXF46488.1 - 0.0057 16.5 0.1 16 5.6 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 PXF46488.1 - 0.032 13.2 0.8 0.38 9.6 0.2 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 PXF46488.1 - 0.058 13.0 0.6 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain PD40 PF07676.12 PXF46488.1 - 0.075 13.0 0.7 61 3.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SBD PF17882.1 PXF46488.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.9 1 0 0 1 1 1 0 OAA-family lectin sugar binding domain Smr PF01713.21 PXF46489.1 - 3.9e-09 36.7 0.4 1.5e-08 34.8 0.1 2.2 3 0 0 3 3 3 1 Smr domain L31 PF09784.9 PXF46489.1 - 0.0049 17.3 0.2 0.011 16.2 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CUE PF02845.16 PXF46489.1 - 0.012 15.4 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 CUE domain AATF-Che1 PF13339.6 PXF46489.1 - 0.027 15.1 1.2 0.055 14.1 1.2 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TPT PF03151.16 PXF46491.1 - 4.5e-27 95.2 17.7 5.1e-27 95.0 17.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF46491.1 - 1.1e-05 25.6 24.1 0.00025 21.2 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family SecE PF00584.20 PXF46493.1 - 1.4e-13 50.5 0.0 1.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SNF2_N PF00176.23 PXF46494.1 - 2.4e-59 200.8 0.2 4.3e-57 193.4 0.2 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF46494.1 - 2.5e-17 63.2 0.0 5.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 PXF46494.1 - 1e-09 38.6 5.8 2.9e-09 37.1 5.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF46494.1 - 1.5e-08 34.4 5.7 3.2e-08 33.3 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF46494.1 - 4.8e-08 32.7 3.9 6.2e-08 32.4 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF46494.1 - 1.7e-06 27.9 3.2 3.4e-06 26.9 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PXF46494.1 - 2.7e-06 27.1 5.0 8.6e-05 22.3 5.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PXF46494.1 - 2.5e-05 24.0 5.0 6e-05 22.8 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF46494.1 - 0.00021 21.2 4.7 0.00049 20.1 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF46494.1 - 0.00054 20.2 6.1 0.0023 18.2 6.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PXF46494.1 - 0.0041 17.2 5.2 0.008 16.3 5.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 PXF46494.1 - 0.0061 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TerY_C PF15616.6 PXF46494.1 - 0.018 15.2 1.4 0.05 13.7 1.4 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C2HC5 PF06221.13 PXF46494.1 - 0.051 13.6 1.3 0.16 12.0 1.3 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Peptidase_U57 PF05582.12 PXF46494.1 - 0.059 12.6 0.2 0.059 12.6 0.2 1.8 2 0 0 2 2 2 0 YabG peptidase U57 zf-ANAPC11 PF12861.7 PXF46494.1 - 0.16 12.0 1.5 0.35 10.9 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PXF46494.1 - 0.21 11.4 1.1 0.61 9.9 1.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 PXF46494.1 - 0.22 11.4 2.0 0.56 10.1 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 PXF46494.1 - 0.58 9.8 2.2 1.2 8.8 2.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Peptidase_M75 PF09375.10 PXF46495.1 - 9.6e-05 22.0 0.6 0.00016 21.3 0.6 1.4 1 1 0 1 1 1 1 Imelysin BBE PF08031.12 PXF46496.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Peptidase_M75 PF09375.10 PXF46497.1 - 4.8e-08 32.8 0.0 7.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Imelysin IBR PF01485.21 PXF46498.1 - 5.6e-10 39.3 25.4 1.3e-06 28.5 7.2 5.1 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 PXF46498.1 - 2.1e-06 27.5 7.8 2.1e-06 27.5 7.8 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF46498.1 - 4.7e-06 26.8 7.5 4.7e-06 26.8 7.5 5.2 3 1 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 PXF46498.1 - 9.6e-05 22.3 7.7 9.6e-05 22.3 7.7 4.3 5 0 0 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF46498.1 - 0.00054 19.9 6.7 0.00054 19.9 6.7 3.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PXF46498.1 - 0.0012 18.7 10.4 0.0012 18.7 10.4 4.5 3 3 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF4522 PF15022.6 PXF46499.1 - 0.24 11.6 4.5 0.87 9.9 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4522) PyrI_C PF02748.15 PXF46499.1 - 0.81 9.6 4.5 2.3 8.2 0.0 3.5 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Snapin_Pallidin PF14712.6 PXF46499.1 - 2 8.9 10.8 0.43 11.0 1.1 3.2 3 0 0 3 3 3 0 Snapin/Pallidin Zn_Tnp_IS1595 PF12760.7 PXF46499.1 - 6.5 6.8 7.7 0.78 9.8 3.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Citrate_synt PF00285.21 PXF46501.1 - 6.5e-103 344.6 0.0 7.8e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sacchrp_dh_NADP PF03435.18 PXF46502.1 - 3.5e-13 49.9 0.0 6.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 PXF46502.1 - 2.3e-06 27.2 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 PXF46502.1 - 3e-05 24.0 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF46502.1 - 4e-05 23.6 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PXF46502.1 - 4.4e-05 22.8 0.0 6.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 PXF46502.1 - 0.00017 21.1 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 PXF46502.1 - 0.00035 20.7 0.0 0.056 13.6 0.1 2.7 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 PXF46502.1 - 0.00078 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 PXF46502.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PXF46502.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PXF46502.1 - 0.045 14.2 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 PXF46502.1 - 0.067 12.3 0.1 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain MINDY_DUB PF04424.13 PXF46503.1 - 1.7e-26 92.5 0.0 2.9e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase PH_TFIIH PF08567.11 PXF46504.1 - 5.6e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 PXF46504.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 BSD domain 5HT_transport_N PF03491.13 PXF46506.1 - 0.087 13.0 0.2 0.3 11.3 0.2 1.9 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Connexin PF00029.19 PXF46506.1 - 0.62 9.8 5.1 1.2 8.9 5.1 1.4 1 0 0 1 1 1 0 Connexin Det1 PF09737.9 PXF46507.1 - 3.6e-56 191.0 0.0 2.1e-55 188.5 0.0 2.2 2 1 0 2 2 2 1 De-etiolated protein 1 Det1 ERM PF00769.19 PXF46508.1 - 2e-05 24.5 15.5 2e-05 24.5 15.5 11.1 2 2 10 12 12 12 3 Ezrin/radixin/moesin family Spc7 PF08317.11 PXF46508.1 - 8.5e-05 21.6 287.7 0.00019 20.4 25.0 12.7 1 1 16 17 17 17 13 Spc7 kinetochore protein Tropomyosin PF00261.20 PXF46508.1 - 0.0022 17.4 46.7 0.0022 17.4 46.7 10.1 2 2 4 8 8 8 4 Tropomyosin ParD_like PF11903.8 PXF46508.1 - 0.11 12.6 2.7 1.4 9.0 0.5 4.1 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system TPT PF03151.16 PXF46509.1 - 1.4e-19 70.6 26.5 1.7e-19 70.3 26.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PXF46509.1 - 2.6e-05 23.6 28.3 3.6e-05 23.1 28.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF46509.1 - 0.00097 19.3 42.4 0.012 15.7 16.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Rad1 PF02144.16 PXF46510.1 - 8.4e-16 57.8 0.0 4.4e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Tim17 PF02466.19 PXF46511.1 - 1.7e-14 54.1 6.4 2.5e-14 53.6 6.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4401 PF14351.6 PXF46511.1 - 0.028 13.8 1.6 0.04 13.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) DUF2177 PF09945.9 PXF46512.1 - 0.29 11.2 1.8 0.63 10.1 1.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) AA_kinase PF00696.28 PXF46513.1 - 1.2e-18 67.6 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 PXF46513.1 - 3.5e-05 24.0 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF46513.1 - 0.00032 21.1 0.0 0.00068 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF46513.1 - 0.0039 17.1 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF46513.1 - 0.097 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thymidylat_synt PF00303.19 PXF46514.1 - 3e-114 380.7 0.0 3.6e-114 380.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 PXF46514.1 - 2.3e-32 111.9 0.0 3.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase AAA_12 PF13087.6 PXF46515.1 - 1e-37 129.7 0.0 2.7e-37 128.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PXF46515.1 - 8.5e-27 94.6 0.1 8.5e-27 94.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PXF46515.1 - 1.5e-06 28.6 0.0 8.3e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PXF46515.1 - 2e-05 24.0 0.2 0.16 11.2 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 PXF46515.1 - 0.00036 20.4 0.0 3.6 7.3 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PXF46515.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PXF46515.1 - 0.0064 16.2 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PXF46515.1 - 0.13 12.5 0.0 18 5.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PXF46515.1 - 0.17 11.3 0.1 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DNA_ligase_ZBD PF03119.16 PXF46515.1 - 2 8.5 4.1 60 3.8 0.2 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Ribosomal_L23 PF00276.20 PXF46516.1 - 5.7e-10 39.4 0.0 7.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Epimerase PF01370.21 PXF46517.1 - 8e-24 84.4 0.0 1.1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 PXF46517.1 - 1.5e-15 56.7 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) GDP_Man_Dehyd PF16363.5 PXF46517.1 - 8.3e-09 35.3 0.0 3.1e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PXF46517.1 - 4.7e-08 33.1 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PXF46517.1 - 1.6e-06 27.4 0.0 3.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 PXF46517.1 - 1.4e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PXF46517.1 - 2.3e-05 24.4 0.2 0.00012 22.1 0.2 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PXF46517.1 - 6.2e-05 22.3 0.0 0.068 12.3 0.0 2.7 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PXF46517.1 - 0.00027 20.2 0.0 0.056 12.6 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PXF46517.1 - 0.00043 19.5 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain F420_oxidored PF03807.17 PXF46517.1 - 0.0088 16.6 0.0 0.04 14.5 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PXF46517.1 - 0.019 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lipase_GDSL_3 PF14606.6 PXF46517.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family zf-C6H2 PF15801.5 PXF46518.1 - 0.89 9.9 7.1 10 6.5 2.1 2.5 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Prok-RING_4 PF14447.6 PXF46518.1 - 1 9.2 9.3 2.8 7.9 0.7 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 p450 PF00067.22 PXF46519.1 - 1.3e-52 179.1 0.0 4.2e-48 164.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L6 PF00347.23 PXF46520.1 - 1.4e-26 93.0 2.0 4.3e-16 59.4 0.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DnaJ_CXXCXGXG PF00684.19 PXF46521.1 - 3.8e-06 27.2 10.4 1e-05 25.8 10.5 1.8 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PXF46521.1 - 0.29 11.1 11.8 0.39 10.7 1.3 3.1 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 PXF46521.1 - 1 9.5 7.4 1.5 9.0 0.7 2.6 1 1 1 2 2 2 0 zinc RING finger of MSL2 Galactosyl_T PF01762.21 PXF46522.1 - 1.6e-05 24.8 0.0 4.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase zf-RING_2 PF13639.6 PXF46524.1 - 6.7e-09 35.9 13.8 1e-08 35.4 13.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF46524.1 - 4.7e-07 29.4 5.6 8.7e-07 28.6 5.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF46524.1 - 5e-07 29.5 12.6 8e-07 28.8 12.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF46524.1 - 1.3e-06 28.2 10.4 1.9e-06 27.6 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF46524.1 - 0.00018 21.3 9.2 0.00028 20.7 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF46524.1 - 0.00049 20.1 11.0 0.001 19.0 11.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PXF46524.1 - 0.0036 17.6 16.2 0.013 15.7 16.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF46524.1 - 0.041 13.9 7.0 0.073 13.1 7.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PXF46524.1 - 0.043 13.4 9.5 0.068 12.8 9.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 PXF46524.1 - 0.26 11.3 8.7 0.47 10.5 8.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PXF46524.1 - 3.6 7.8 9.7 13 6.0 9.6 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Chromo PF00385.24 PXF46525.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.14 PXF46527.1 - 4.9e-09 35.7 0.0 8.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 THF_DHG_CYH_C PF02882.19 PXF46530.1 - 1.4e-71 239.0 0.7 5e-71 237.2 0.2 2.1 2 1 1 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PXF46530.1 - 2.6e-38 130.8 0.1 4.2e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 PXF46530.1 - 0.00028 19.9 0.4 0.00046 19.2 0.4 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DRTGG PF07085.12 PXF46530.1 - 0.14 12.0 0.3 3 7.7 0.0 2.3 2 0 0 2 2 2 0 DRTGG domain tRNA-synt_1 PF00133.22 PXF46531.1 - 5.6e-42 143.8 0.0 4.2e-16 58.3 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PXF46531.1 - 2.6e-19 69.3 0.4 1.7e-08 33.6 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PXF46531.1 - 1.4e-12 47.8 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PXF46531.1 - 1.6e-07 31.0 0.1 4.7e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF46531.1 - 0.015 14.3 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) SCO1-SenC PF02630.14 PXF46532.1 - 8.5e-42 142.3 0.0 1.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 PXF46532.1 - 0.00092 19.1 0.0 0.01 15.8 0.0 2.1 2 1 0 2 2 2 1 AhpC/TSA family Ank_2 PF12796.7 PXF46533.1 - 8.1e-21 74.4 0.0 1.3e-08 35.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF46533.1 - 1.1e-15 57.7 1.0 4.2e-06 27.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF46533.1 - 1.2e-14 52.9 0.2 7.5e-05 22.8 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PXF46533.1 - 6.5e-14 51.8 2.1 1.5e-05 25.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PXF46533.1 - 1.4e-12 47.5 0.2 9e-05 22.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF2520 PF10728.9 PXF46533.1 - 0.044 13.5 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) Arm PF00514.23 PXF46534.1 - 0.00011 22.1 0.5 0.0044 17.0 0.0 2.6 2 1 0 2 2 2 1 Armadillo/beta-catenin-like repeat DRIM PF07539.12 PXF46534.1 - 0.027 12.8 1.2 0.028 12.7 0.3 1.3 1 1 0 1 1 1 0 Down-regulated in metastasis DUF1028 PF06267.12 PXF46534.1 - 0.038 13.8 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF1028) APH PF01636.23 PXF46534.1 - 0.095 12.6 2.9 2.4 8.0 1.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_19 PF14559.6 PXF46536.1 - 9.5e-06 26.0 6.4 0.012 16.1 0.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46536.1 - 0.0099 15.9 0.5 0.0099 15.9 0.5 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46536.1 - 0.028 15.2 22.9 0.053 14.4 0.7 5.7 3 2 4 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PXF46536.1 - 0.029 14.8 1.3 0.05 14.1 0.1 1.9 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 PXF46536.1 - 0.12 13.1 1.8 22 6.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SspK PF08176.12 PXF46537.1 - 0.18 12.1 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Slu7 PF11708.8 PXF46540.1 - 9e-75 251.9 7.3 9e-75 251.9 7.3 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF2771 PF10969.8 PXF46540.1 - 0.016 15.2 0.4 5.7 7.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2771) BTK PF00779.19 PXF46540.1 - 0.027 14.3 1.1 0.056 13.3 1.1 1.5 1 0 0 1 1 1 0 BTK motif zf-CCHC_4 PF14392.6 PXF46540.1 - 0.042 13.6 0.8 0.1 12.3 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Vfa1 PF08432.10 PXF46540.1 - 0.24 11.7 16.1 2 8.7 5.7 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Proteasome PF00227.26 PXF46541.1 - 7.5e-55 185.4 0.1 9.8e-55 185.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF46541.1 - 1.5e-14 53.3 0.2 3e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Baculo_gp64 PF03273.13 PXF46541.1 - 0.085 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family FKBP_C PF00254.28 PXF46542.1 - 7.8e-09 35.7 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CPT_N PF16484.5 PXF46542.1 - 1.2 9.2 3.5 3.9 7.5 2.1 2.2 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus eRF1_1 PF03463.15 PXF46543.1 - 8.2e-38 129.3 0.0 1.3e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 PXF46543.1 - 6.3e-24 84.6 0.0 2.2e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 PXF46543.1 - 1.8e-22 80.1 0.0 3.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 WD40 PF00400.32 PXF46544.1 - 1.6e-36 123.6 15.7 7.7e-06 26.6 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46544.1 - 1.1e-19 70.5 0.0 0.0003 21.0 0.0 5.6 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF46544.1 - 3.5e-06 26.2 2.7 1.1 8.2 0.1 4.1 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PXF46544.1 - 0.01 15.2 0.0 2.7 7.2 0.0 2.8 4 0 0 4 4 4 0 WD40-like domain Nup160 PF11715.8 PXF46544.1 - 0.032 12.9 0.0 5.2 5.6 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PXF46544.1 - 0.045 12.3 0.0 9.5 4.6 0.0 3.2 4 0 0 4 4 4 0 Cytochrome D1 heme domain Cadherin_C PF01049.17 PXF46544.1 - 0.13 12.6 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region Ribosomal_S9 PF00380.19 PXF46545.1 - 1.1e-48 164.7 0.2 3.8e-48 163.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 SUIM_assoc PF16619.5 PXF46545.1 - 0.053 13.6 0.8 0.13 12.4 0.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 PXF46546.1 - 0.0011 19.0 4.7 0.061 13.5 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF46546.1 - 0.0019 18.3 0.5 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat NOPS PF08075.11 PXF46546.1 - 0.0022 18.1 0.3 0.013 15.7 0.3 2.2 2 0 0 2 2 2 1 NOPS (NUC059) domain TPR_11 PF13414.6 PXF46546.1 - 0.016 14.9 1.7 2.4 7.9 0.4 3.2 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.6 PXF46546.1 - 0.018 15.3 1.0 0.24 11.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF86 PF01934.17 PXF46546.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF86 ANAPC3 PF12895.7 PXF46546.1 - 0.064 13.5 1.6 0.83 9.9 1.6 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PXF46546.1 - 0.091 12.8 0.2 0.091 12.8 0.2 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 PXF46546.1 - 0.14 12.2 1.4 5.9 7.0 0.1 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 PXF46546.1 - 0.16 12.7 0.2 1.1 9.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46546.1 - 0.18 12.1 0.9 1.3 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46546.1 - 0.76 9.7 3.6 0.82 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat GCR1_C PF12550.8 PXF46546.1 - 1.3 9.4 6.5 1 9.7 0.5 2.4 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Myb_DNA-binding PF00249.31 PXF46547.1 - 2.7e-10 40.3 0.2 1.2e-09 38.2 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain GlnE PF03710.15 PXF46550.1 - 0.044 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase PAP2 PF01569.21 PXF46551.1 - 1.5e-14 53.9 9.6 2.6e-14 53.1 9.6 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 PXF46551.1 - 0.0021 17.8 18.7 0.0081 15.9 18.6 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 PXF46551.1 - 0.27 11.8 4.2 0.096 13.2 1.1 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal POP1 PF06978.11 PXF46552.1 - 3.6e-26 92.4 14.3 9.8e-15 55.1 0.2 2.8 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 PXF46552.1 - 2.9e-19 69.2 0.0 8.3e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 PXF46552.1 - 5e-07 29.3 0.0 0.031 13.7 0.0 3.1 3 0 0 3 3 3 3 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PXF46552.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Mpp10 PF04006.12 PXF46553.1 - 6e-76 256.2 45.4 6e-76 256.2 45.4 3.9 2 2 0 2 2 2 1 Mpp10 protein DUF974 PF06159.13 PXF46555.1 - 6.4e-37 127.7 0.0 9.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 PXF46555.1 - 6.1e-07 29.2 0.4 0.0014 18.1 0.1 3.0 3 0 0 3 3 3 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 PXF46555.1 - 0.0072 16.5 0.1 3.6 7.8 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Tubulin PF00091.25 PXF46556.1 - 1.4e-64 217.9 0.0 2.4e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PXF46556.1 - 6.2e-43 146.0 0.0 9.2e-43 145.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PXF46556.1 - 0.0031 17.2 0.0 0.0087 15.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PXF46556.1 - 0.1 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Tubulin like Bromodomain PF00439.25 PXF46557.1 - 1.6e-18 66.5 0.0 2.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 PXF46557.1 - 1.5e-09 38.1 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF46557.1 - 6e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF46557.1 - 1.6e-05 25.2 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_pol_A_exo1 PF01612.20 PXF46559.1 - 1.9e-28 99.3 0.0 2.5e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LigT_PEase PF02834.16 PXF46559.1 - 0.039 14.2 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 LigT like Phosphoesterase 2-oxoacid_dh PF00198.23 PXF46560.1 - 4.3e-66 222.7 0.0 5.8e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PXF46560.1 - 8.8e-16 57.5 0.1 1.5e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PXF46560.1 - 1.7e-07 31.4 3.0 1.5e-05 25.3 0.0 2.8 2 0 0 2 2 2 2 e3 binding domain GCV_H PF01597.19 PXF46560.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein BRCT_2 PF16589.5 PXF46561.1 - 5.6e-08 33.1 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PXF46561.1 - 1.2e-07 31.6 0.1 2.2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 PXF46561.1 - 4.7e-06 26.8 0.1 8.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 PXF46561.1 - 0.00028 21.2 0.1 0.00061 20.1 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FMN_bind_2 PF04299.12 PXF46561.1 - 0.0029 17.4 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Putative FMN-binding domain HD-ZIP_N PF04618.12 PXF46561.1 - 0.061 13.8 1.3 0.11 13.1 0.5 1.7 2 0 0 2 2 2 0 HD-ZIP protein N terminus DUF3128 PF11326.8 PXF46562.1 - 1.6e-17 63.7 1.0 1.6e-17 63.7 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) DUF3314 PF11771.8 PXF46562.1 - 0.055 13.6 1.4 0.066 13.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) CHCH PF06747.13 PXF46562.1 - 0.07 13.3 0.4 1 9.6 0.1 2.5 2 0 0 2 2 2 0 CHCH domain Sigma70_r4 PF04545.16 PXF46563.1 - 4.1e-21 74.2 2.2 5.2e-20 70.7 0.5 2.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 PXF46563.1 - 5.4e-21 74.1 0.0 1.4e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 PXF46563.1 - 1.7e-18 66.5 0.0 4.6e-15 55.5 0.1 2.6 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 PXF46563.1 - 2e-09 37.3 0.6 5.2e-09 36.0 0.6 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 PXF46563.1 - 0.0021 17.7 0.2 0.039 13.6 0.0 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 ELL PF10390.9 PXF46564.1 - 2.7e-07 30.4 4.1 1e-06 28.5 4.1 1.9 1 1 0 1 1 1 1 RNA polymerase II elongation factor ELL Occludin_ELL PF07303.13 PXF46564.1 - 0.0058 17.3 2.2 0.061 14.1 0.1 2.7 1 1 3 4 4 4 1 Occludin homology domain DUF3545 PF12065.8 PXF46564.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Virulence_fact PF13769.6 PXF46564.1 - 0.12 12.6 1.7 0.56 10.5 0.1 2.4 2 0 0 2 2 2 0 Virulence factor CorA PF01544.18 PXF46565.1 - 4.5e-10 39.3 6.7 1e-09 38.1 6.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Cyclin_C_2 PF16899.5 PXF46565.1 - 0.05 14.0 0.2 0.15 12.5 0.2 1.8 1 0 0 1 1 1 0 Cyclin C-terminal domain HemY_N PF07219.13 PXF46565.1 - 0.69 10.1 5.3 0.22 11.7 0.3 2.4 2 0 0 2 2 2 0 HemY protein N-terminus NDK PF00334.19 PXF46566.1 - 2.7e-54 182.8 0.0 3.1e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF5559 PF17714.1 PXF46567.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5559) Sec3-PIP2_bind PF15277.6 PXF46568.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Pescadillo_N PF06732.11 PXF46569.1 - 1.8e-101 339.3 0.3 1.8e-101 339.3 0.3 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 PXF46569.1 - 0.0033 17.8 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Dopey_N PF04118.14 PXF46570.1 - 0.006 15.7 0.0 0.0095 15.1 0.0 1.4 1 0 0 1 1 1 1 Dopey, N-terminal ERO1 PF04137.15 PXF46571.1 - 3.9e-107 358.5 0.2 5.1e-107 358.1 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Chordopox_A33R PF05966.12 PXF46571.1 - 0.098 11.9 0.8 0.15 11.3 0.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Zip PF02535.22 PXF46571.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Clathrin PF00637.20 PXF46572.1 - 1.7e-09 37.7 0.0 5.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PXF46572.1 - 0.16 11.9 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Clathrin-H-link Methyltransf_23 PF13489.6 PXF46572.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CtaG_Cox11 PF04442.14 PXF46573.1 - 2e-61 206.4 0.1 2.9e-61 205.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Glyco_transf_41 PF13844.6 PXF46574.1 - 5.1e-135 450.5 0.0 3.6e-69 233.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 PXF46574.1 - 1.4e-33 114.3 2.2 4e-07 29.6 0.1 6.5 2 1 4 6 6 6 6 TPR repeat TPR_8 PF13181.6 PXF46574.1 - 2.5e-23 80.3 0.2 6.3e-05 22.9 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46574.1 - 4.1e-23 80.2 3.2 0.0001 22.0 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46574.1 - 2.3e-21 74.1 8.5 0.0021 18.0 0.1 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 PXF46574.1 - 1e-20 72.6 8.6 0.00036 20.7 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46574.1 - 3.5e-15 55.4 11.3 0.0062 17.3 0.7 6.8 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 PXF46574.1 - 3e-14 53.4 10.7 1.5e-05 25.5 1.0 4.8 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46574.1 - 4.2e-14 51.5 2.8 0.029 14.4 0.0 5.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PXF46574.1 - 1.5e-13 50.9 10.9 5.3e-06 26.6 0.1 4.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 PXF46574.1 - 9.9e-13 47.5 19.5 0.11 12.4 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 PXF46574.1 - 2.6e-08 34.2 11.6 0.0033 17.9 2.4 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 PXF46574.1 - 0.0002 20.7 1.3 0.0016 17.7 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.7 PXF46574.1 - 0.078 13.2 1.7 0.5 10.6 0.1 2.8 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_4 PF07721.14 PXF46574.1 - 0.14 12.9 7.8 21 6.1 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF46574.1 - 0.22 12.2 0.5 2.1e+02 2.9 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF46574.1 - 0.53 10.6 2.1 4.7 7.5 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PXF46574.1 - 0.98 9.6 7.5 21 5.4 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 PXF46574.1 - 1.4 9.4 6.2 41 4.6 0.1 3.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain STAG PF08514.11 PXF46577.1 - 3e-17 62.5 0.3 9.6e-16 57.7 0.0 2.7 2 1 0 2 2 2 1 STAG domain HEAT PF02985.22 PXF46577.1 - 7.3e-08 32.0 0.4 0.68 10.3 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 PXF46577.1 - 8.5e-07 29.3 0.6 0.00017 21.9 0.1 3.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 PXF46577.1 - 5.6e-06 26.5 1.5 1.3e-05 25.3 0.1 2.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 PXF46577.1 - 8.5e-05 22.3 0.2 0.023 14.4 0.0 2.7 1 1 0 2 2 2 1 Domain of unknown function (DUF4042) SMG1 PF15785.5 PXF46577.1 - 0.024 13.1 0.0 0.039 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Nipped-B_C PF12830.7 PXF46577.1 - 0.026 14.5 0.1 0.097 12.6 0.0 2.0 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus FAM76 PF16046.5 PXF46577.1 - 0.074 12.4 2.6 0.1 12.0 1.2 1.7 2 0 0 2 2 2 0 FAM76 protein Adaptin_N PF01602.20 PXF46577.1 - 0.076 11.6 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region DUF4441 PF14536.6 PXF46577.1 - 0.44 10.7 1.6 4.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) M PF02370.16 PXF46577.1 - 1.4 9.7 5.5 5.6 7.9 1.1 2.6 1 1 1 2 2 2 0 M protein repeat DUF4337 PF14235.6 PXF46577.1 - 2.2 8.4 3.7 3.8 7.6 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) H_PPase PF03030.16 PXF46578.1 - 4.2e-13 48.8 4.6 4.2e-13 48.8 4.6 1.7 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase MttA_Hcf106 PF02416.16 PXF46578.1 - 2.4 7.6 4.3 1.5 8.2 0.4 2.3 2 0 0 2 2 2 0 mttA/Hcf106 family Plant_tran PF04827.14 PXF46579.1 - 1.4e-50 171.7 0.0 2.1e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF46579.1 - 1.7e-05 24.6 0.0 3.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease MTS PF05175.14 PXF46583.1 - 1.7e-10 40.7 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PXF46583.1 - 3.1e-06 27.8 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46583.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 PXF46583.1 - 3e-05 23.8 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 PXF46583.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PXF46583.1 - 0.0048 17.6 0.0 0.0086 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF46583.1 - 0.0054 16.6 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PXF46583.1 - 0.0098 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 PXF46583.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 PXF46583.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_11 PF08241.12 PXF46583.1 - 0.06 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PXF46583.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6-adenineMlase PF10237.9 PXF46583.1 - 0.093 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase NUDIX PF00293.28 PXF46584.1 - 4.5e-16 59.1 0.1 6.2e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.6 PXF46584.1 - 3.5e-12 46.0 1.8 6.1e-12 45.2 1.8 1.3 1 0 0 1 1 1 1 Nudix N-terminal Auto_anti-p27 PF06677.12 PXF46584.1 - 0.015 15.5 1.2 0.029 14.5 1.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 PXF46584.1 - 0.016 15.2 1.5 0.024 14.7 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon ADK_lid PF05191.14 PXF46584.1 - 0.024 14.6 0.6 0.68 10.0 0.1 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 PXF46584.1 - 0.5 10.5 2.2 0.91 9.7 2.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain NUC153 PF08159.12 PXF46585.1 - 5.7e-09 35.6 0.9 5.7e-09 35.6 0.9 3.1 3 0 0 3 3 3 1 NUC153 domain TB2_DP1_HVA22 PF03134.19 PXF46586.1 - 1.7e-17 63.1 1.8 2.5e-17 62.6 1.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2339 PF10101.9 PXF46586.1 - 0.032 12.8 2.0 0.035 12.7 2.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Retrotran_gag_2 PF14223.6 PXF46596.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ish1 PF10281.9 PXF46597.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Methyltransf_11 PF08241.12 PXF46599.1 - 1.4e-12 48.1 0.0 3.4e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46599.1 - 5e-12 45.9 0.0 7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46599.1 - 3.1e-11 43.8 0.0 6.3e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF46599.1 - 5.2e-09 36.2 0.0 7.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF46599.1 - 1.6e-08 34.2 0.0 2.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PXF46599.1 - 3.4e-07 30.9 0.0 6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PXF46599.1 - 0.00058 20.9 0.0 0.0016 19.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF46599.1 - 0.00072 19.0 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 PXF46599.1 - 0.0062 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PXF46599.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain SAM_MT PF04445.13 PXF46599.1 - 0.19 11.1 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Surp PF01805.20 PXF46600.1 - 2.4e-32 110.7 0.5 2.3e-15 56.3 0.0 2.7 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 PXF46600.1 - 6.8e-24 84.9 7.2 6.8e-24 84.9 7.2 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 PXF46600.1 - 1.5e-08 34.3 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family AAA_23 PF13476.6 PXF46600.1 - 2.7 8.5 7.0 1 9.8 2.4 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PXF46601.1 - 8.6e-20 70.9 0.0 4.9e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Thioredoxin PF00085.20 PXF46601.1 - 2e-09 37.4 0.0 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin AAA_16 PF13191.6 PXF46601.1 - 0.0016 18.9 0.0 0.0092 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 PXF46601.1 - 0.0031 18.1 0.0 0.0088 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Thioredoxin_8 PF13905.6 PXF46601.1 - 0.0043 17.4 0.1 0.54 10.6 0.1 3.9 4 1 1 5 5 5 1 Thioredoxin-like TraF PF13728.6 PXF46601.1 - 0.006 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein TsaE PF02367.17 PXF46601.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 PXF46601.1 - 0.025 13.8 0.1 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 PXF46601.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thioredoxin_7 PF13899.6 PXF46601.1 - 0.045 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like SRP54 PF00448.22 PXF46601.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 PXF46601.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CN_hydrolase PF00795.22 PXF46602.1 - 5.5e-34 117.7 0.0 7.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 PXF46602.1 - 5.9e-25 87.8 0.0 2.7e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 NAD synthase MGDG_synth PF06925.11 PXF46603.1 - 2.4e-28 99.4 0.0 3.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 PXF46603.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 PXF46603.1 - 1.2e-06 29.0 0.1 3.6e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PXF46603.1 - 1.4e-05 24.7 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF46603.1 - 0.003 17.6 0.7 0.026 14.5 1.1 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 PXF46603.1 - 0.058 13.8 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PXF46603.1 - 0.6 10.5 8.6 6.8 7.1 8.6 2.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4370 PF14290.6 PXF46604.1 - 0.0049 16.8 0.3 0.0097 15.8 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4370) 5_3_exonuc PF01367.20 PXF46604.1 - 0.023 15.3 0.4 0.21 12.2 0.1 2.1 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Elf4 PF07011.11 PXF46604.1 - 0.047 13.6 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Early Flowering 4 domain Laminin_II PF06009.12 PXF46604.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Laminin Domain II HTH_45 PF14947.6 PXF46604.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix UbiA PF01040.18 PXF46605.1 - 8.1e-45 153.1 12.4 9.4e-45 152.9 12.4 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.32 PXF46606.1 - 1.1e-19 70.4 9.8 5.1e-05 23.9 0.0 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46606.1 - 5.9e-05 23.3 0.0 16 5.9 0.0 5.1 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PXF46606.1 - 0.03 14.8 0.1 31 5.2 0.0 4.0 3 0 0 3 3 3 0 PQQ-like domain Aminotran_1_2 PF00155.21 PXF46607.1 - 1.1e-37 130.1 0.0 1.2e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PXF46607.1 - 1.6e-12 46.9 0.0 2.1e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Mon1 PF03164.14 PXF46608.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Ndr PF03096.14 PXF46609.1 - 3.8e-17 61.9 0.0 4.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 PXF46609.1 - 9.7e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF46609.1 - 5.5e-05 22.9 0.0 7.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PXF46609.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2452 PF10504.9 PXF46610.1 - 0.049 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Brix PF04427.18 PXF46611.1 - 3.8e-33 115.2 0.2 5.2e-33 114.8 0.2 1.2 1 0 0 1 1 1 1 Brix domain NINJA_B PF16136.5 PXF46611.1 - 0.033 14.5 1.1 0.074 13.4 1.1 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal PUF PF00806.19 PXF46612.1 - 1.4e-64 210.3 5.0 5.7e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 PXF46612.1 - 6.6e-05 23.3 0.7 2.3 8.6 0.0 3.8 2 2 1 3 3 3 3 CPL (NUC119) domain Ribosomal_S26e PF01283.19 PXF46613.1 - 3.1e-40 137.0 8.1 3.6e-40 136.8 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PHF5 PF03660.14 PXF46613.1 - 0.0065 16.7 1.2 0.0081 16.3 1.2 1.2 1 0 0 1 1 1 1 PHF5-like protein NIF PF03031.18 PXF46614.1 - 2.6e-24 85.8 0.1 4e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 PXF46614.1 - 3.8e-05 23.3 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DEK_C PF08766.11 PXF46615.1 - 6.2e-06 26.0 0.3 6.2e-06 26.0 0.3 2.5 3 1 0 3 3 3 1 DEK C terminal domain CHZ PF09649.10 PXF46615.1 - 0.00082 18.8 2.8 0.002 17.6 2.8 1.7 1 0 0 1 1 1 1 Histone chaperone domain CHZ HTH_26 PF13443.6 PXF46615.1 - 0.046 14.2 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TMEM51 PF15345.6 PXF46615.1 - 4.4 7.1 10.7 0.86 9.4 7.2 1.5 2 0 0 2 2 2 0 Transmembrane protein 51 DUF565 PF04483.12 PXF46616.1 - 4.3e-15 56.0 0.0 8.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF565) Cyclin_N PF00134.23 PXF46617.1 - 0.0025 17.6 0.1 0.068 12.9 0.0 2.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 PXF46617.1 - 0.3 11.2 1.1 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat TRAPPC10 PF12584.8 PXF46620.1 - 4e-07 29.9 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 zf-RING_4 PF14570.6 PXF46622.1 - 1.7e-19 69.3 10.5 3.7e-19 68.2 10.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PXF46622.1 - 7.5e-07 28.9 9.9 1.3e-06 28.1 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 PXF46622.1 - 3.4e-06 26.6 5.9 3.4e-06 26.6 5.9 3.0 2 1 1 3 3 2 1 Rtf2 RING-finger RRM_1 PF00076.22 PXF46622.1 - 2.5e-05 24.0 0.0 7.2e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 PXF46622.1 - 2.6e-05 24.4 11.8 4.8e-05 23.6 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 PXF46622.1 - 0.016 15.1 4.3 0.031 14.2 4.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 PXF46622.1 - 0.02 15.0 4.1 0.046 13.8 4.1 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 PXF46622.1 - 0.09 12.7 10.8 0.16 11.8 10.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF46622.1 - 0.55 10.1 9.8 10 6.1 9.6 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 PXF46622.1 - 5.8 7.1 8.3 11 6.2 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 PXF46622.1 - 8.6 6.6 9.1 24 5.2 9.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ANAPC_CDC26 PF10471.9 PXF46623.1 - 1.5e-07 32.1 2.8 1.8e-07 31.9 2.8 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Sld5 PF05916.11 PXF46624.1 - 0.0067 16.9 0.2 0.014 15.8 0.2 1.6 1 1 0 1 1 1 1 GINS complex protein Sulfotransfer_2 PF03567.14 PXF46625.1 - 1.4e-06 28.4 1.8 2.1e-06 27.8 1.8 1.4 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 PXF46625.1 - 5.6e-05 22.2 1.7 8.9e-05 21.5 1.7 1.3 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase LIDHydrolase PF10230.9 PXF46626.1 - 2.7e-32 112.4 0.0 3.4e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 PXF46626.1 - 4.2e-09 37.3 6.6 5.9e-09 36.9 6.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF46626.1 - 0.00069 19.3 0.4 0.0013 18.5 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 PXF46626.1 - 0.0016 18.6 0.2 0.0046 17.1 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 PXF46626.1 - 0.0053 16.6 0.0 1.7 8.5 0.1 2.3 2 0 0 2 2 2 2 Serine hydrolase Cation_efflux PF01545.21 PXF46627.1 - 0.00019 21.3 5.9 0.00029 20.6 5.9 1.3 1 0 0 1 1 1 1 Cation efflux family CTV_P6 PF06706.11 PXF46627.1 - 0.0031 17.2 0.9 0.0082 15.8 0.9 1.7 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein Shisa PF13908.6 PXF46628.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Rax2 PF12768.7 PXF46628.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CKS PF01111.19 PXF46629.1 - 1.2e-36 124.7 1.1 1.4e-36 124.6 1.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CDC45 PF02724.14 PXF46630.1 - 3.3e-126 422.1 5.0 1.4e-91 307.7 0.6 2.2 1 1 1 2 2 2 2 CDC45-like protein Rrp15p PF07890.12 PXF46631.1 - 1.7e-12 47.8 17.5 3.5e-12 46.8 17.0 1.7 1 1 1 2 2 2 1 Rrp15p LepA_C PF06421.12 PXF46631.1 - 0.1 12.8 7.4 2.8 8.1 1.3 2.3 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Clat_adaptor_s PF01217.20 PXF46632.1 - 3.7e-05 23.7 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ubiq_cyt_C_chap PF03981.12 PXF46633.1 - 9e-22 77.7 0.2 1.3e-21 77.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone PK PF00224.21 PXF46634.1 - 2.4e-69 233.9 0.0 1.3e-68 231.5 0.0 2.1 2 1 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PXF46634.1 - 5.2e-24 84.7 0.0 2.3e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PXF46634.1 - 7.8e-06 25.2 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GGDEF_2 PF17853.1 PXF46634.1 - 0.095 13.0 0.0 1.5 9.1 0.0 2.7 2 1 0 2 2 2 0 GGDEF-like domain Ran_BP1 PF00638.18 PXF46635.1 - 2e-46 157.2 4.6 3.4e-46 156.5 4.6 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.14 PXF46635.1 - 6.5e-05 22.7 2.7 0.00012 21.9 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.23 PXF46635.1 - 0.037 14.0 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 WH1 domain Raffinose_syn PF05691.12 PXF46636.1 - 3.2e-54 184.0 0.0 4.7e-53 180.1 0.0 2.4 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 TAF6_C PF07571.13 PXF46637.1 - 6.1e-29 100.2 0.0 1.3e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PXF46637.1 - 2.3e-17 62.9 0.1 5.1e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 PXF46637.1 - 0.6 10.5 7.5 11 6.3 6.7 3.1 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Ssu72 PF04722.13 PXF46638.1 - 6.8e-59 198.7 0.0 7.8e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Radical_SAM PF04055.21 PXF46639.1 - 7.2e-10 39.5 0.0 1.8e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 PXF46639.1 - 2.1e-08 34.5 0.0 4.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family DUF3082 PF11282.8 PXF46640.1 - 1.3e-16 60.6 3.4 1.3e-16 60.6 3.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3082) DHC PF09626.10 PXF46640.1 - 0.1 13.5 0.5 0.21 12.5 0.3 1.6 1 1 1 2 2 2 0 Dihaem cytochrome c VIT1 PF01988.19 PXF46640.1 - 1.6 8.6 4.1 5.1 6.9 4.1 1.7 1 1 0 1 1 1 0 VIT family Methyltransf_8 PF05148.15 PXF46641.1 - 4.6e-63 213.0 0.0 2e-59 201.1 0.0 2.0 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 PXF46641.1 - 4.7e-06 27.2 0.0 6.7e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46641.1 - 0.00019 21.3 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46641.1 - 0.00065 20.4 0.0 0.46 11.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.14 PXF46641.1 - 0.0028 17.2 0.0 0.012 15.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain DEAD PF00270.29 PXF46642.1 - 1.6e-38 132.2 0.3 1.6e-38 132.2 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF46642.1 - 5.6e-32 110.4 0.2 3.2e-31 108.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF46642.1 - 2.8e-05 24.2 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PXF46642.1 - 0.00025 21.4 0.2 0.005 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 PXF46642.1 - 0.0086 16.1 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain tRNA-synt_1b PF00579.25 PXF46642.1 - 0.015 14.6 0.1 0.52 9.6 0.0 2.8 2 1 0 3 3 3 0 tRNA synthetases class I (W and Y) Dimerisation PF08100.11 PXF46643.1 - 0.13 12.3 0.6 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain SAPS PF04499.15 PXF46644.1 - 3.7e-12 45.8 0.1 0.00034 19.5 0.0 3.3 3 1 1 4 4 4 3 SIT4 phosphatase-associated protein LSM PF01423.22 PXF46645.1 - 1.4e-20 72.7 0.4 1.6e-20 72.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain RMI1_N PF08585.12 PXF46646.1 - 6.2e-16 58.8 0.0 1.8e-10 41.0 0.0 2.5 1 1 1 2 2 2 2 RecQ mediated genome instability protein ABC_membrane PF00664.23 PXF46647.1 - 1e-32 113.9 11.3 1.4e-32 113.5 11.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PXF46647.1 - 9.4e-32 110.4 0.0 1.9e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PXF46647.1 - 5.7e-07 29.2 0.0 2.8e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PXF46647.1 - 0.00074 19.5 0.1 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 PXF46647.1 - 0.0017 17.6 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 PXF46647.1 - 0.0027 18.0 0.0 0.035 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PXF46647.1 - 0.0065 16.2 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 PXF46647.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF46647.1 - 0.0094 16.3 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PXF46647.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PXF46647.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 PXF46647.1 - 0.062 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 PXF46647.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 PXF46647.1 - 0.13 12.2 0.0 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 PXF46647.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MgtE PF01769.16 PXF46647.1 - 7.9 6.9 10.2 2 8.8 4.6 2.5 2 0 0 2 2 2 0 Divalent cation transporter CAF1 PF04857.20 PXF46648.1 - 3.9e-70 236.6 0.1 4.7e-70 236.3 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease SRP_SPB PF02978.19 PXF46649.1 - 1.3e-08 35.3 0.9 1.3e-08 35.3 0.9 1.5 2 0 0 2 2 2 1 Signal peptide binding domain L_lactis_RepB_C PF06430.12 PXF46649.1 - 0.16 12.0 0.1 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus CBS PF00571.28 PXF46650.1 - 8.4e-24 83.8 2.3 4.2e-13 49.5 0.4 2.8 2 0 0 2 2 2 2 CBS domain DHH PF01368.20 PXF46650.1 - 1.2e-10 41.5 0.5 2.7e-10 40.4 0.5 1.6 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 PXF46650.1 - 6e-05 23.5 0.2 0.00014 22.3 0.2 1.7 1 1 0 1 1 1 1 DHHA1 domain Ribosomal_S10 PF00338.22 PXF46651.1 - 8.1e-30 102.9 0.1 9.9e-30 102.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UB2H PF14814.6 PXF46651.1 - 0.042 13.9 0.0 9.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain DUF3929 PF13066.6 PXF46651.1 - 0.051 13.6 0.2 0.098 12.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) DUF5415 PF17436.2 PXF46651.1 - 0.15 12.1 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5415) NTP_transf_9 PF04248.12 PXF46652.1 - 1.7e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF427) BCDHK_Adom3 PF10436.9 PXF46653.1 - 2.1e-48 164.2 0.0 3.3e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PXF46653.1 - 4.6e-08 33.5 0.0 9.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PXF46653.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gag_p10 PF02337.17 PXF46654.1 - 0.047 13.6 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Retroviral GAG p10 protein DHHC PF01529.20 PXF46654.1 - 0.061 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase TAF PF02969.17 PXF46655.1 - 2.5e-20 72.4 0.0 1.1e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 PXF46655.1 - 2.6e-11 43.7 0.0 6.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 PXF46655.1 - 0.00028 21.2 0.2 0.00082 19.7 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PXF46655.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FBPase PF00316.20 PXF46656.1 - 1.7e-18 66.7 0.0 5.5e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DMPK_coil PF08826.10 PXF46657.1 - 0.029 14.5 0.2 0.051 13.7 0.2 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like Dus PF01207.17 PXF46658.1 - 2.5e-68 230.4 0.1 4e-68 229.8 0.1 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 PXF46658.1 - 0.00027 20.4 0.2 0.00048 19.6 0.2 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 PXF46658.1 - 0.0026 17.0 0.0 0.34 10.1 0.0 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase ThiG PF05690.14 PXF46658.1 - 0.0043 16.4 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG BKACE PF05853.12 PXF46658.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme SOR_SNZ PF01680.17 PXF46658.1 - 0.02 14.7 0.7 0.036 13.9 0.7 1.4 1 0 0 1 1 1 0 SOR/SNZ family PP_kinase_C_1 PF17941.1 PXF46658.1 - 0.031 13.8 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 TMP-TENI PF02581.17 PXF46658.1 - 0.032 13.6 0.2 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase His_biosynth PF00977.21 PXF46658.1 - 0.048 13.1 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein Cgr1 PF03879.14 PXF46658.1 - 0.21 12.0 0.7 0.38 11.2 0.7 1.3 1 0 0 1 1 1 0 Cgr1 family DDOST_48kD PF03345.14 PXF46659.1 - 5.9e-82 275.7 0.0 7e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 PXF46659.1 - 0.0062 16.9 0.0 0.057 13.9 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4350) UvrD-helicase PF00580.21 PXF46661.1 - 3.2e-97 325.9 0.4 2.5e-68 230.9 0.1 4.3 2 2 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PXF46661.1 - 6.4e-64 216.5 0.0 1.9e-63 215.0 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PXF46661.1 - 2.4e-42 144.7 0.0 1.7e-33 116.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 PXF46661.1 - 8.7e-10 38.3 0.1 4.9e-09 35.9 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PXF46661.1 - 1.4e-07 31.5 0.0 4.5e-05 23.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 PXF46661.1 - 4.7e-07 29.8 0.1 0.019 14.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 PXF46661.1 - 0.00027 20.6 1.2 1.2 8.7 0.0 4.4 4 1 1 5 5 5 1 AAA domain AAA_11 PF13086.6 PXF46661.1 - 0.0003 20.7 0.0 0.0003 20.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain ResIII PF04851.15 PXF46661.1 - 0.0045 17.0 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 PXF46661.1 - 0.084 13.2 0.1 0.73 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PXF46661.1 - 0.14 12.5 0.4 3.7 7.8 0.0 3.4 3 1 1 4 4 4 0 AAA domain RRM_1 PF00076.22 PXF46662.1 - 1.3e-16 60.2 0.0 2.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF46662.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif PPR_2 PF13041.6 PXF46663.1 - 5.4e-80 263.4 0.1 2.9e-11 43.4 0.1 14.1 9 2 5 14 14 14 11 PPR repeat family PPR_3 PF13812.6 PXF46663.1 - 6.8e-52 173.4 1.1 3.2e-07 30.3 0.0 11.6 10 3 2 12 12 12 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF46663.1 - 1.4e-48 162.3 18.5 9.6e-05 22.0 0.1 15.9 15 1 0 15 15 15 10 PPR repeat PPR PF01535.20 PXF46663.1 - 7.5e-46 151.2 18.8 2.1e-05 24.4 0.0 17.8 19 2 0 19 19 19 9 PPR repeat PPR_long PF17177.4 PXF46663.1 - 7.8e-19 67.9 11.7 5.1e-09 35.8 0.5 6.9 2 2 3 7 7 7 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PXF46663.1 - 4e-05 24.0 4.7 6 7.5 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46663.1 - 4.5e-05 23.9 8.8 8.7 7.5 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat HMW1C_N PF18071.1 PXF46663.1 - 0.00033 20.5 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 HMW1C N-terminal TPR_7 PF13176.6 PXF46663.1 - 0.00059 19.7 3.3 2 8.7 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Exog_C PF18026.1 PXF46663.1 - 0.011 15.7 0.2 44 4.2 0.0 4.8 6 0 0 6 6 5 0 Endo/exonuclease (EXOG) C-terminal domain BKACE PF05853.12 PXF46663.1 - 0.015 14.6 0.1 0.95 8.7 0.0 3.3 3 2 0 3 3 3 0 beta-keto acid cleavage enzyme TPR_2 PF07719.17 PXF46663.1 - 2.8 8.3 4.1 27 5.2 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Tim44 PF04280.15 PXF46664.1 - 2.5e-36 125.0 0.1 2.5e-36 125.0 0.1 2.7 4 0 0 4 4 4 1 Tim44-like domain RNA_pol_A_bac PF01000.26 PXF46665.1 - 3.6e-25 88.5 0.0 9e-25 87.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PXF46665.1 - 4.4e-19 67.7 0.0 6.9e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 PXF46665.1 - 0.039 14.1 0.8 0.08 13.1 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNase_H_2 PF13482.6 PXF46666.1 - 0.067 13.2 0.0 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 RNase_H superfamily HTH_Tnp_Tc5 PF03221.16 PXF46668.1 - 4e-06 26.7 0.3 7.4e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 PXF46668.1 - 0.087 12.5 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease DDE_1 PF03184.19 PXF46669.1 - 3.7e-12 46.2 0.0 5.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CLP_protease PF00574.23 PXF46670.1 - 3.3e-82 274.8 0.0 4e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease Dynamin_M PF01031.20 PXF46671.1 - 2.7e-95 318.9 0.0 9.7e-95 317.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 PXF46671.1 - 1.6e-48 164.9 0.0 4e-48 163.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PXF46671.1 - 3.5e-24 84.8 5.9 8.4e-24 83.6 5.9 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PXF46671.1 - 0.00031 20.8 0.1 0.0011 19.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 PXF46671.1 - 0.00049 20.0 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PXF46671.1 - 0.038 14.4 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 PXF46671.1 - 6.4 6.0 7.0 3.5 6.9 0.1 2.8 3 0 0 3 3 3 0 AIG1 family SURF2 PF05477.11 PXF46672.1 - 6.2e-24 85.0 18.3 9.2e-24 84.4 18.3 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF2281 PF10047.9 PXF46672.1 - 1.5 9.5 8.0 4.6 8.0 8.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Nop14 PF04147.12 PXF46672.1 - 2.7 6.1 39.8 3.7 5.7 39.8 1.1 1 0 0 1 1 1 0 Nop14-like family PsiA PF06952.11 PXF46672.1 - 9.7 5.4 12.3 2.1 7.6 0.8 2.4 2 0 0 2 2 2 0 PsiA protein E2F_TDP PF02319.20 PXF46673.1 - 2.7e-07 30.5 0.0 4.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain CCT PF06203.14 PXF46674.1 - 1.2e-13 50.9 15.7 1.8e-13 50.3 15.7 1.3 1 0 0 1 1 1 1 CCT motif Spt20 PF12090.8 PXF46674.1 - 0.08 12.5 11.0 0.15 11.7 11.0 1.4 1 0 0 1 1 1 0 Spt20 family Paf1 PF03985.13 PXF46674.1 - 0.11 11.5 8.9 0.15 11.0 8.9 1.2 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 PXF46674.1 - 0.14 12.2 29.2 0.22 11.5 29.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PALP PF00291.25 PXF46675.1 - 1.7e-63 214.8 1.4 1.9e-63 214.6 1.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hydrolase PF00702.26 PXF46675.1 - 0.09 13.1 0.1 0.44 10.8 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 2Fe-2S_thioredx PF01257.19 PXF46676.1 - 1.1e-57 193.9 0.0 1.4e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin TFIID-18kDa PF02269.16 PXF46678.1 - 1.7e-21 76.1 0.5 1.9e-21 75.9 0.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit AAA_22 PF13401.6 PXF46679.1 - 7.1e-05 23.1 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PXF46679.1 - 9.5e-05 22.8 0.1 0.00032 21.1 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PXF46679.1 - 0.00017 21.3 0.3 0.00033 20.4 0.3 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PXF46679.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 PXF46679.1 - 0.00055 20.4 0.2 0.0018 18.7 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 PXF46679.1 - 0.0044 16.6 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 PXF46679.1 - 0.019 14.7 0.0 0.059 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 PXF46679.1 - 0.021 14.6 0.2 0.046 13.4 0.2 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 PXF46679.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 PXF46679.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PXF46679.1 - 0.034 14.5 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PXF46679.1 - 0.053 13.4 0.2 0.27 11.1 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 PXF46679.1 - 0.054 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CAP PF00188.26 PXF46679.1 - 0.066 14.1 0.1 0.19 12.6 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich secretory protein family NTPase_1 PF03266.15 PXF46679.1 - 0.066 13.1 1.6 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 PXF46679.1 - 0.072 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PXF46679.1 - 0.082 13.1 0.2 0.3 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PXF46679.1 - 0.14 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PXF46679.1 - 0.16 12.5 0.0 0.51 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PXF46679.1 - 0.17 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PXF46680.1 - 4.3e-29 100.1 14.1 1.3e-06 29.0 0.2 6.9 8 0 0 8 8 6 4 WD domain, G-beta repeat Hira PF07569.11 PXF46680.1 - 8.6e-29 100.8 0.0 8.6e-29 100.8 0.0 2.9 2 1 0 2 2 1 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 PXF46680.1 - 7.3e-17 61.4 0.2 0.0021 18.3 0.0 6.4 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF46680.1 - 0.00094 18.2 0.0 1.2 8.0 0.0 3.9 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 PXF46680.1 - 0.0074 16.2 0.1 0.0074 16.2 0.1 3.5 2 2 0 2 2 1 1 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 PXF46680.1 - 0.0093 15.9 0.0 1.4 8.9 0.0 3.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Endostatin PF06482.11 PXF46680.1 - 0.068 12.6 14.6 0.14 11.6 14.6 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GREB1 PF15782.5 PXF46680.1 - 0.99 6.4 24.9 1.5 5.9 24.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 PXF46680.1 - 1.1 8.0 30.6 1.7 7.3 30.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 PXF46680.1 - 1.1 9.3 24.1 2 8.5 24.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pkinase_fungal PF17667.1 PXF46680.1 - 1.6 7.4 9.2 3 6.5 9.2 1.4 1 0 0 1 1 1 0 Fungal protein kinase GAGA_bind PF06217.12 PXF46680.1 - 1.6 8.9 19.2 3.3 7.9 19.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.13 PXF46680.1 - 2.5 8.0 57.2 0.12 12.4 50.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 PXF46680.1 - 3.4 6.0 3.7 6 5.2 3.7 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PTPRCAP PF15713.5 PXF46680.1 - 7.8 6.8 25.7 21 5.4 25.7 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Lin-8 PF03353.15 PXF46680.1 - 8.7 5.8 32.4 15 5.0 32.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 PXF46680.1 - 8.9 5.0 17.5 14 4.3 17.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DnaJ PF00226.31 PXF46682.1 - 4e-16 58.9 0.4 2.9e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Presenilin PF01080.17 PXF46682.1 - 0.6 8.8 1.5 0.83 8.4 1.5 1.2 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 PXF46682.1 - 0.98 9.1 4.7 1.6 8.4 4.7 1.3 1 0 0 1 1 1 0 AAA domain Auts2 PF15336.6 PXF46682.1 - 1.3 9.1 9.7 0.13 12.4 5.2 1.5 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein MDM10 PF12519.8 PXF46682.1 - 1.6 7.5 5.5 2.6 6.8 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Glyco_hydro_14 PF01373.17 PXF46683.1 - 4.4e-93 312.4 0.0 5.1e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 PXF46683.1 - 0.046 13.3 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 NICE-3 PF07406.11 PXF46684.1 - 0.0099 15.9 0.2 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 NICE-3 protein WD40 PF00400.32 PXF46686.1 - 0.002 18.9 0.6 3.9 8.5 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46686.1 - 0.0027 18.0 0.0 0.1 12.9 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain YpsA PF06908.11 PXF46686.1 - 0.0087 16.1 0.0 0.061 13.3 0.0 2.1 1 1 0 2 2 2 1 YspA SLOG family Ribosomal_L44 PF00935.19 PXF46687.1 - 1.2e-36 125.0 12.4 1.8e-36 124.5 12.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 PXF46687.1 - 0.025 14.9 1.9 0.044 14.1 1.9 1.4 1 0 0 1 1 1 0 Cathelicidin PCI PF01399.27 PXF46688.1 - 2.8e-09 37.4 0.6 1.5e-08 35.1 0.4 2.2 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 PXF46688.1 - 0.021 14.7 0.2 0.11 12.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46688.1 - 0.084 13.0 0.3 0.084 13.0 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 PXF46689.1 - 5.2e-19 68.1 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 PXF46689.1 - 1.6e-11 43.8 0.0 4.4e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Sec63 Brl domain Mak16 PF04874.14 PXF46689.1 - 0.18 12.4 14.4 0.52 11.0 14.4 1.7 1 0 0 1 1 1 0 Mak16 protein C-terminal region SDA1 PF05285.12 PXF46689.1 - 0.4 10.0 10.2 0.63 9.4 10.2 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PXF46689.1 - 2.8 6.0 14.9 4.5 5.4 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family CK_II_beta PF01214.18 PXF46690.1 - 2.2e-77 259.0 0.0 2.9e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Chromo PF00385.24 PXF46693.1 - 9.7e-07 28.6 0.5 1.7e-06 27.8 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_4 PF13359.6 PXF46694.1 - 2.8e-24 85.6 0.0 4.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pox_polyA_pol PF03296.13 PXF46697.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain IspD PF01128.19 PXF46698.1 - 1.6e-57 194.8 0.0 2.4e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 PXF46698.1 - 6.9e-11 42.8 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain RAB3GAP2_N PF14655.6 PXF46699.1 - 1.7e-22 80.3 0.0 6.6e-16 58.6 0.1 3.6 2 2 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Lebercilin PF15619.6 PXF46700.1 - 2.5e-06 27.3 24.2 2.5e-06 27.3 24.2 11.1 2 2 11 13 13 13 4 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 PXF46700.1 - 0.00038 20.5 20.3 0.00038 20.5 20.3 15.2 1 1 15 18 18 18 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PPR_2 PF13041.6 PXF46701.1 - 1.9e-39 133.6 4.5 9.3e-10 38.6 0.2 5.2 3 2 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 PXF46701.1 - 3.8e-33 113.4 0.3 2.8e-14 52.9 0.0 4.1 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 PXF46701.1 - 2.8e-25 87.7 5.1 1e-06 28.3 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 PXF46701.1 - 1.5e-21 75.1 4.1 6.7e-06 26.0 0.1 6.1 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 PXF46701.1 - 8.4e-15 54.7 0.4 1.2e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 PXF46701.1 - 0.024 13.5 0.0 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 PXF46701.1 - 0.029 14.2 0.0 1.9 8.3 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression Vps23_core PF09454.10 PXF46701.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Vps23 core domain GP57 PF17594.2 PXF46701.1 - 0.12 12.1 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 RPM2 PF08579.11 PXF46701.1 - 0.14 12.6 0.0 4.8 7.6 0.0 2.4 1 1 2 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2921 PF11145.8 PXF46702.1 - 0.24 9.2 1.0 0.34 8.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Dynamitin PF04912.14 PXF46704.1 - 9.5e-31 107.5 14.6 2.6e-30 106.1 14.6 1.6 1 1 0 1 1 1 1 Dynamitin Bacillus_HBL PF05791.11 PXF46704.1 - 0.033 14.0 1.4 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IPPT PF01715.17 PXF46704.1 - 0.12 12.1 3.0 0.11 12.3 1.7 1.6 1 1 0 1 1 1 0 IPP transferase Dynactin_p22 PF07426.11 PXF46704.1 - 0.18 11.6 7.6 0.054 13.3 3.8 2.1 2 1 0 2 2 2 0 Dynactin subunit p22 Baculo_PEP_C PF04513.12 PXF46704.1 - 0.22 11.6 6.5 5.3 7.1 0.2 3.0 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 PXF46704.1 - 0.64 10.4 14.6 0.24 11.8 0.4 5.5 3 2 4 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 PXF46704.1 - 0.73 10.3 10.0 0.66 10.5 0.1 4.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 PXF46704.1 - 1.4 9.1 10.3 3.1 8.0 1.2 3.5 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 PXF46704.1 - 1.5 8.9 8.1 0.63 10.1 2.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 PXF46704.1 - 2 8.8 12.4 4.3 7.7 0.4 3.5 3 1 0 3 3 3 0 Csm1 N-terminal domain TP_methylase PF00590.20 PXF46706.1 - 1.6e-19 70.7 0.2 2.5e-19 70.1 0.2 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Smg4_UPF3 PF03467.15 PXF46707.1 - 2.5e-29 102.5 0.0 5.4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.22 PXF46707.1 - 0.036 13.9 0.0 1.4 8.7 0.2 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 PXF46707.1 - 1.9 6.9 6.8 2.5 6.6 6.8 1.1 1 0 0 1 1 1 0 Macoilin family Sigma70_r2 PF04542.14 PXF46708.1 - 6.7e-20 70.6 0.1 1.7e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PXF46708.1 - 2.5e-19 68.5 0.2 4.9e-17 61.2 0.2 2.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 PXF46708.1 - 4.9e-06 26.5 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 PXF46708.1 - 0.022 14.4 0.7 0.12 12.1 0.5 2.5 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_10 PF04967.12 PXF46708.1 - 0.031 14.1 0.0 7 6.5 0.0 3.1 3 0 0 3 3 3 0 HTH DNA binding domain Sigma70_r1_2 PF00140.20 PXF46708.1 - 0.052 13.6 0.6 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 HTH_Crp_2 PF13545.6 PXF46708.1 - 0.058 13.4 0.1 2.4 8.2 0.0 2.9 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1289 PF06945.13 PXF46708.1 - 2.9 7.7 5.6 6 6.7 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF5071 PF16804.5 PXF46709.1 - 0.066 13.5 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) His_Phos_1 PF00300.22 PXF46710.1 - 4.2e-16 59.2 0.1 1.7e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldedh PF00171.22 PXF46711.1 - 9.1e-14 50.8 5.4 1.1e-09 37.3 2.2 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_S21e PF01249.18 PXF46711.1 - 0.023 14.8 0.7 0.38 10.9 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein S21e DUF1542 PF07564.11 PXF46711.1 - 0.58 10.3 7.0 0.073 13.2 2.6 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Nup35_RRM PF05172.13 PXF46712.1 - 1.3e-12 47.5 0.0 3.5e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 PXF46712.1 - 0.0028 17.6 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ATP-synt PF00231.19 PXF46713.1 - 3e-89 299.5 0.4 3.5e-89 299.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase DUF5557 PF17712.1 PXF46713.1 - 0.086 12.8 0.2 12 5.9 0.0 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5557) Inositol_P PF00459.25 PXF46714.1 - 1e-65 222.0 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family 3-PAP PF12578.8 PXF46715.1 - 0.056 13.2 0.7 0.079 12.7 0.7 1.2 1 0 0 1 1 1 0 Myotubularin-associated protein ATP-synt PF00231.19 PXF46716.1 - 8.4e-83 278.3 1.6 9.9e-83 278.1 1.6 1.1 1 0 0 1 1 1 1 ATP synthase MutS_I PF01624.20 PXF46717.1 - 0.02 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 MutS domain I DUF2774 PF11242.8 PXF46717.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) LSM PF01423.22 PXF46718.1 - 1.2e-10 41.0 0.1 1.7e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 LSM domain SpoIIE PF07228.12 PXF46719.1 - 2.6e-11 43.8 0.3 3.7e-11 43.3 0.3 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PXF46719.1 - 9.9e-05 22.1 0.4 0.012 15.2 0.2 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PXF46719.1 - 0.0016 18.1 0.3 0.0026 17.4 0.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LytR_C PF13399.6 PXF46719.1 - 0.016 16.2 3.0 0.24 12.4 0.3 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator UCH PF00443.29 PXF46720.1 - 2.8e-39 135.2 0.0 2.1e-29 102.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF46720.1 - 0.0017 18.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Serglycin PF04360.12 PXF46720.1 - 0.59 10.1 10.3 4.8 7.1 10.2 2.2 2 1 0 2 2 2 0 Serglycin Glycos_transf_1 PF00534.20 PXF46721.1 - 6.5e-34 116.9 0.0 1e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF46721.1 - 2.6e-27 95.9 0.0 4.6e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF46721.1 - 2.7e-20 73.0 0.0 1e-19 71.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PXF46721.1 - 1.1e-14 55.1 0.0 4.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 PXF46721.1 - 3.9e-13 49.6 0.0 1.3e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 PXF46721.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Redoxin PF08534.10 PXF46721.1 - 0.045 13.4 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Redoxin Glyco_transf_5 PF08323.11 PXF46721.1 - 0.16 11.6 0.0 38 3.9 0.0 3.0 2 2 2 4 4 4 0 Starch synthase catalytic domain Acyltransferase PF01553.21 PXF46722.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1242 PF06842.12 PXF46723.1 - 1.5e-20 72.6 2.9 2.3e-20 72.1 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) SOUL PF04832.12 PXF46724.1 - 1.5e-31 109.9 0.0 1.1e-29 103.8 0.0 2.5 1 1 0 1 1 1 1 SOUL heme-binding protein DUF2576 PF10845.8 PXF46724.1 - 0.019 14.6 0.3 0.042 13.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Peptidase_M22 PF00814.25 PXF46725.1 - 3.3e-86 289.3 0.0 4.1e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 PXF46725.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus ANAPC4_WD40 PF12894.7 PXF46726.1 - 1.4e-13 51.0 0.0 0.025 14.9 0.0 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF46726.1 - 4.1e-12 46.4 9.0 0.037 14.9 0.4 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 PXF46726.1 - 1.5e-05 25.0 0.0 0.011 15.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PXF46726.1 - 0.00012 21.9 0.3 0.0071 16.3 0.0 3.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 PXF46726.1 - 0.031 12.8 0.1 0.13 10.8 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 PXF46726.1 - 0.095 11.4 0.0 3.3 6.4 0.0 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region HEAT_2 PF13646.6 PXF46727.1 - 6.1e-37 125.9 18.5 6.4e-14 52.1 3.2 4.5 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.22 PXF46727.1 - 3.3e-14 51.8 8.8 0.048 13.9 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat HEAT_PBS PF03130.16 PXF46727.1 - 7.8e-11 41.6 18.5 0.038 14.7 0.0 7.6 8 0 0 8 8 7 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 PXF46727.1 - 9.1e-08 32.5 16.5 1.7 9.2 0.9 7.0 6 1 2 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 PXF46727.1 - 0.00037 20.6 2.6 0.11 12.5 0.1 4.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PXF46727.1 - 0.0043 17.0 7.5 14 5.9 0.1 5.5 4 1 2 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PXF46727.1 - 0.019 13.5 2.0 0.074 11.6 0.1 2.7 3 1 0 4 4 4 0 Adaptin N terminal region DUF2019 PF09450.10 PXF46727.1 - 0.049 13.6 0.3 0.43 10.6 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2019) RasGEF_N_2 PF14663.6 PXF46727.1 - 0.082 13.3 0.6 1.6 9.2 0.0 3.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vitellogenin_N PF01347.22 PXF46727.1 - 0.12 10.8 0.1 0.34 9.3 0.1 1.7 1 1 0 1 1 1 0 Lipoprotein amino terminal region DUF4042 PF13251.6 PXF46727.1 - 0.4 10.4 1.8 14 5.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DDRGK PF09756.9 PXF46729.1 - 2.5 7.7 16.1 4 7.0 16.1 1.3 1 0 0 1 1 1 0 DDRGK domain TFIIB PF00382.19 PXF46731.1 - 2.6e-27 94.7 1.1 1.5e-12 47.4 0.2 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 PXF46731.1 - 3.2e-12 46.7 8.6 3.2e-12 46.7 8.6 2.5 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 PXF46731.1 - 1.3e-09 37.4 1.6 1.3e-09 37.4 0.2 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 PXF46731.1 - 0.0029 17.3 0.5 0.0056 16.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2H2_12 PF18658.1 PXF46731.1 - 0.035 13.7 0.1 0.097 12.3 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type RB_B PF01857.20 PXF46731.1 - 0.073 13.1 0.4 0.073 13.1 0.4 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 PXF46731.1 - 0.12 11.9 1.6 1.3 8.6 1.6 2.4 1 1 0 1 1 1 0 zinc-ribbon domain LSM PF01423.22 PXF46732.1 - 3.6e-16 58.6 0.2 4.5e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain CBM-like PF14683.6 PXF46732.1 - 0.18 11.7 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III ABC2_membrane PF01061.24 PXF46733.1 - 2.4e-39 134.9 7.2 3.3e-39 134.5 7.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PXF46733.1 - 2e-25 89.9 0.0 4.5e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PXF46733.1 - 1.2e-05 25.8 0.0 2.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 PXF46733.1 - 2e-05 23.9 4.3 2e-05 23.9 4.3 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 PXF46733.1 - 2.1e-05 24.5 0.3 0.22 11.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PXF46733.1 - 6.7e-05 23.2 0.0 0.0002 21.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain Rad17 PF03215.15 PXF46733.1 - 0.00013 22.0 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 PXF46733.1 - 0.0011 18.9 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AFG1_ATPase PF03969.16 PXF46733.1 - 0.0046 15.9 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 AFG1-like ATPase AAA_33 PF13671.6 PXF46733.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF46733.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 PXF46733.1 - 0.012 15.4 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PXF46733.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 PXF46733.1 - 0.019 14.0 0.5 0.038 13.0 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein SMC_N PF02463.19 PXF46733.1 - 0.021 14.2 0.2 0.56 9.6 0.2 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 PXF46733.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 PXF46733.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 PXF46733.1 - 0.034 14.2 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PXF46733.1 - 0.041 14.1 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF46733.1 - 0.043 13.5 0.3 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 PXF46733.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_24 PF13479.6 PXF46733.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PXF46733.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PXF46733.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PXF46733.1 - 0.069 13.7 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 PXF46733.1 - 0.088 12.7 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 PXF46733.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PXF46733.1 - 0.18 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TAF1_subA PF14929.6 PXF46734.1 - 7.1e-13 48.7 0.1 1.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 TAF RNA Polymerase I subunit A Utp11 PF03998.13 PXF46735.1 - 4.4e-51 174.2 19.8 4.9e-51 174.0 19.8 1.0 1 0 0 1 1 1 1 Utp11 protein NtCtMGAM_N PF16863.5 PXF46735.1 - 0.003 17.7 1.7 0.11 12.8 0.6 2.3 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase COP-gamma_platf PF08752.10 PXF46735.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain FlaG PF03646.15 PXF46735.1 - 3.1 8.0 6.4 3.6 7.8 0.6 2.3 2 0 0 2 2 2 0 FlaG protein Bac_surface_Ag PF01103.23 PXF46736.1 - 3e-11 43.4 0.2 1.5e-10 41.1 0.2 2.0 1 1 0 1 1 1 1 Surface antigen SWIRM-assoc_2 PF16496.5 PXF46736.1 - 0.17 10.7 5.1 0.28 10.0 5.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 PXF46737.1 - 2.5e-06 27.7 0.0 7.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Pkinase PF00069.25 PXF46738.1 - 1.3e-63 214.9 0.0 1.9e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46738.1 - 3.9e-26 91.9 0.0 5.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UbiA PF01040.18 PXF46739.1 - 3.7e-39 134.6 12.1 4.4e-39 134.3 12.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family CoA_binding_3 PF13727.6 PXF46739.1 - 0.083 12.9 0.7 0.083 12.9 0.7 1.9 3 0 0 3 3 3 0 CoA-binding domain DUF2358 PF10184.9 PXF46740.1 - 3.7e-25 88.4 0.0 5.6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 PXF46740.1 - 0.089 13.4 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain REJ PF02010.15 PXF46741.1 - 8.5e-23 80.9 0.0 1.1e-17 64.0 0.1 3.3 2 1 0 3 3 3 3 REJ domain TIG PF01833.24 PXF46741.1 - 0.0015 18.5 2.1 0.092 12.8 0.1 3.7 3 0 0 3 3 3 1 IPT/TIG domain REJ PF02010.15 PXF46742.1 - 5.6e-15 55.1 0.1 1.3e-09 37.4 0.0 3.1 2 1 2 4 4 4 3 REJ domain PKD PF00801.20 PXF46742.1 - 0.00062 19.6 0.0 0.011 15.5 0.0 3.2 2 0 0 2 2 2 1 PKD domain PhoU PF01895.19 PXF46742.1 - 0.084 13.3 0.2 1.7 9.2 0.0 2.4 1 1 1 2 2 2 0 PhoU domain Thioredoxin PF00085.20 PXF46743.1 - 9.9e-07 28.7 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF46743.1 - 0.0063 15.9 0.0 0.0074 15.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 PXF46743.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 PXF46743.1 - 0.12 12.6 0.0 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin SNF2_N PF00176.23 PXF46744.1 - 2.6e-49 167.8 0.1 5.4e-49 166.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF46744.1 - 5e-19 68.7 0.1 2.9e-17 63.0 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF46744.1 - 4.4e-13 49.6 0.0 1.9e-12 47.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF46744.1 - 2.4e-05 24.2 0.0 7.7e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3854 PF12965.7 PXF46744.1 - 0.026 14.5 0.1 0.085 12.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Thioredoxin PF00085.20 PXF46745.1 - 2.4e-12 46.7 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PXF46745.1 - 0.00029 21.1 0.1 0.03 14.7 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PXF46745.1 - 0.0017 18.8 0.2 0.011 16.2 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PXF46745.1 - 0.0032 17.4 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 PXF46745.1 - 0.032 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 PXF46745.1 - 0.034 14.0 0.1 0.061 13.1 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 PXF46745.1 - 0.04 14.1 0.5 0.098 12.8 0.5 1.7 1 1 0 1 1 1 0 Thioredoxin-like Spt4 PF06093.13 PXF46746.1 - 1.2e-29 102.2 0.8 1.6e-29 101.8 0.8 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TBCC PF07986.12 PXF46746.1 - 0.0065 16.2 0.2 0.0081 15.9 0.2 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Coronavirus_5 PF05528.11 PXF46746.1 - 0.087 12.8 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein CwfJ_C_1 PF04677.15 PXF46747.1 - 3.1e-21 75.5 0.0 5.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 PXF46747.1 - 0.024 15.5 0.1 0.052 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 DcpS_C PF11969.8 PXF46747.1 - 0.23 12.0 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Cse1 PF08506.10 PXF46748.1 - 2.4e-06 26.6 0.0 0.00021 20.3 0.0 2.8 3 0 0 3 3 3 1 Cse1 HEAT_2 PF13646.6 PXF46748.1 - 0.013 15.8 8.2 6.8 7.2 0.0 4.5 4 1 1 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 PXF46748.1 - 0.023 14.9 0.1 0.17 12.1 0.1 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 PXF46748.1 - 0.026 14.4 0.0 0.94 9.4 0.0 3.3 3 0 0 3 3 3 0 Importin-beta N-terminal domain Arm PF00514.23 PXF46748.1 - 0.066 13.3 0.4 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PXF46748.1 - 0.68 10.3 5.8 1.5e+02 3.1 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat Thioredoxin PF00085.20 PXF46749.1 - 1.9e-10 40.6 0.1 2.5e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF46749.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF46749.1 - 0.0032 17.8 0.0 0.0046 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Haem_bd PF14376.6 PXF46749.1 - 0.015 15.3 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 Haem-binding domain DUF3398 PF11878.8 PXF46749.1 - 0.031 14.7 0.1 0.047 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) TCL1_MTCP1 PF01840.17 PXF46749.1 - 0.039 13.6 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 TCL1/MTCP1 family Fer2 PF00111.27 PXF46749.1 - 0.067 13.2 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Tmemb_185A PF10269.9 PXF46750.1 - 0.0081 15.9 0.2 0.0099 15.6 0.2 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF973 PF06157.11 PXF46750.1 - 0.012 14.7 0.0 0.012 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Cytochrom_B561 PF03188.16 PXF46750.1 - 0.028 14.5 2.1 0.038 14.1 2.1 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF347 PF03988.12 PXF46750.1 - 0.35 11.1 4.4 0.43 10.8 0.4 2.1 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF2651 PF10852.8 PXF46750.1 - 0.6 10.8 7.9 0.65 10.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2651) DUF202 PF02656.15 PXF46750.1 - 0.63 10.5 4.5 1.3 9.5 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Thioredoxin PF00085.20 PXF46751.1 - 9.2e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF46751.1 - 0.00044 19.7 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF46751.1 - 0.00051 20.3 0.2 0.026 14.9 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF46751.1 - 0.0038 17.2 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PXF46751.1 - 0.0047 17.4 0.1 0.019 15.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain RhoGEF67_u2 PF16614.5 PXF46751.1 - 0.027 14.6 2.1 0.044 13.9 2.1 1.4 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Thioredoxin_7 PF13899.6 PXF46751.1 - 0.045 13.9 0.4 0.071 13.3 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin-like Malectin PF11721.8 PXF46753.1 - 1.1e-11 45.1 0.0 2.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Malectin domain ER_lumen_recept PF00810.18 PXF46754.1 - 0.025 15.4 0.9 0.025 15.4 0.9 1.6 2 0 0 2 2 2 0 ER lumen protein retaining receptor Cadherin_C_2 PF16492.5 PXF46754.1 - 0.66 10.8 5.0 0.2 12.4 1.2 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Acetyltransf_1 PF00583.25 PXF46755.1 - 2.7e-15 56.6 0.0 3.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF46755.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF46755.1 - 1.9e-10 41.0 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF46755.1 - 5e-09 36.0 0.0 7.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 PXF46755.1 - 3.1e-05 24.2 0.0 3.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PXF46755.1 - 0.00052 19.7 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF46755.1 - 0.0046 17.6 0.0 0.0054 17.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PXF46755.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNase PF00565.17 PXF46756.1 - 4.9e-41 139.6 0.0 2.9e-10 40.6 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 PXF46756.1 - 6e-16 58.6 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Tudor domain RIF5_SNase_1 PF18187.1 PXF46756.1 - 0.067 12.9 0.0 1.5 8.5 0.0 2.9 4 0 0 4 4 4 0 TbRIF5 SNase domain 1 DUF1325 PF07039.11 PXF46756.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain SLATT_fungal PF18142.1 PXF46756.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Tropomyosin_1 PF12718.7 PXF46756.1 - 3.1 8.0 4.9 0.54 10.4 0.6 1.8 2 0 0 2 2 2 0 Tropomyosin like Alpha_kinase PF02816.18 PXF46757.1 - 1.7e-29 103.3 0.0 2.3e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family AMMECR1 PF01871.17 PXF46758.1 - 2.2e-44 151.0 0.0 2.6e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DUF1604 PF07713.13 PXF46758.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Atx10homo_assoc PF09759.9 PXF46760.1 - 1.5e-05 24.9 3.0 0.17 11.9 0.0 4.0 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 PXF46760.1 - 0.00037 20.4 0.9 0.53 10.4 0.0 4.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cullin_Nedd8 PF10557.9 PXF46763.1 - 1.8e-23 82.3 0.6 3.1e-23 81.6 0.6 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1803 PF08820.10 PXF46763.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Cullin PF00888.22 PXF46764.1 - 5.4e-102 342.4 0.0 1.9e-101 340.6 0.0 1.7 1 1 0 1 1 1 1 Cullin family V-ATPase_H_C PF11698.8 PXF46764.1 - 0.0082 16.2 0.3 4.1 7.5 0.0 2.9 3 0 0 3 3 3 2 V-ATPase subunit H HTH_24 PF13412.6 PXF46764.1 - 0.02 14.5 0.6 0.058 13.0 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 PXF46764.1 - 0.028 14.2 0.6 1.4 8.8 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 PXF46764.1 - 0.045 13.6 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.12 PXF46764.1 - 0.11 12.3 0.1 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain Gar1 PF04410.14 PXF46765.1 - 4.8e-29 101.1 1.2 5.8e-26 91.1 0.2 2.2 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region SR-25 PF10500.9 PXF46765.1 - 3.3 7.2 16.9 0.53 9.9 8.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.6 PXF46767.1 - 7.9e-08 32.5 11.2 1.9e-07 31.3 11.2 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 PXF46767.1 - 0.00096 19.3 6.2 0.0021 18.2 6.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 PXF46767.1 - 0.0011 18.9 2.5 0.003 17.6 2.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PXF46767.1 - 0.021 14.7 10.1 0.054 13.3 10.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46767.1 - 0.036 14.4 10.8 0.12 12.6 10.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Nop PF01798.18 PXF46767.1 - 0.045 13.2 0.0 0.17 11.3 0.0 2.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Cnd1 PF12717.7 PXF46767.1 - 0.063 13.3 0.0 1.2 9.2 0.0 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Zn_ribbon_17 PF17120.5 PXF46767.1 - 0.068 12.8 7.3 0.2 11.3 7.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HEAT PF02985.22 PXF46767.1 - 0.16 12.3 0.4 11 6.6 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat RINGv PF12906.7 PXF46767.1 - 0.2 11.8 9.0 0.52 10.5 9.0 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 PXF46767.1 - 0.42 10.5 10.7 0.9 9.5 10.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 PXF46767.1 - 0.46 10.8 10.2 1.3 9.4 10.2 1.8 1 1 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 PXF46767.1 - 1.5 8.7 7.2 19 5.1 7.7 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 PXF46767.1 - 3 8.0 7.5 3.5 7.8 4.5 2.7 3 0 0 3 3 3 0 KIAA1045 RING finger PAP_PilO PF06864.12 PXF46768.1 - 0.015 14.2 0.7 0.16 10.7 0.1 2.0 1 1 1 2 2 2 0 Pilin accessory protein (PilO) ATP-synt_E PF05680.12 PXF46768.1 - 0.033 14.5 0.2 0.057 13.8 0.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain Lipin_mid PF16876.5 PXF46768.1 - 0.07 13.3 0.6 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3488 PF11992.8 PXF46768.1 - 0.11 11.4 0.7 0.21 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF3792 PF12670.7 PXF46768.1 - 0.27 11.4 5.4 0.44 10.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF5316 PF17247.2 PXF46768.1 - 1.6 8.8 4.8 2.2 8.4 0.0 3.2 2 2 2 4 4 4 0 Family of unknown function (DUF5316) Mucin PF01456.17 PXF46769.1 - 0.00078 19.4 4.4 0.0019 18.2 4.4 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein UPF0560 PF10577.9 PXF46769.1 - 0.034 12.7 1.1 0.048 12.2 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Epiglycanin_C PF14654.6 PXF46769.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4834 PF16118.5 PXF46769.1 - 0.12 13.3 0.2 0.4 11.7 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 PXF46769.1 - 0.18 12.7 0.5 0.56 11.1 0.5 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Toxin_11 PF07473.11 PXF46769.1 - 0.24 11.5 5.9 0.6 10.2 5.9 1.7 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Gemini_mov PF01708.16 PXF46770.1 - 0.065 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein BPS1 PF05633.11 PXF46771.1 - 0.068 12.2 0.7 0.73 8.8 0.1 1.9 2 0 0 2 2 2 0 Protein BYPASS1-related DUF4061 PF13270.6 PXF46771.1 - 0.16 12.3 7.2 0.35 11.2 2.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) TPR_14 PF13428.6 PXF46772.1 - 0.00079 20.0 3.8 1.8 9.6 0.3 5.5 4 0 0 4 4 4 2 Tetratricopeptide repeat FAD_binding_3 PF01494.19 PXF46773.1 - 8.1e-78 262.1 0.0 1.1e-77 261.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 PXF46773.1 - 2.8e-06 26.6 0.0 7.1e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 PXF46773.1 - 3.3e-05 24.0 0.0 0.00011 22.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF46773.1 - 0.00012 21.8 0.3 0.00056 19.6 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF46773.1 - 0.00047 19.3 0.0 0.0012 18.0 0.0 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 PXF46773.1 - 0.0013 18.1 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PXF46773.1 - 0.0024 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 PXF46773.1 - 0.003 18.1 0.0 0.17 12.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF46773.1 - 0.0037 16.6 0.0 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF46773.1 - 0.0086 15.3 0.0 0.035 13.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF46773.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 PXF46773.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein SLAC1 PF03595.17 PXF46774.1 - 1.7e-25 90.0 44.2 2.3e-25 89.6 44.2 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF563 PF04577.14 PXF46775.1 - 1.8e-17 64.2 0.2 4.5e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF1499 PF07386.11 PXF46776.1 - 1.7e-09 38.2 0.0 3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Abhydrolase_2 PF02230.16 PXF46777.1 - 1.8e-06 27.9 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PXF46777.1 - 0.038 14.6 6.3 0.038 14.6 1.9 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PXF46777.1 - 0.064 12.7 0.0 2.4 7.6 0.0 2.4 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PXF46779.1 - 1.6e-08 34.7 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cas9_b_hairpin PF17893.1 PXF46779.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated endonuclease Cas9 beta-hairpin domain Abhydrolase_6 PF12697.7 PXF46779.1 - 0.0024 18.5 2.1 0.013 16.1 0.5 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Dala_Dala_lig_C PF07478.13 PXF46780.1 - 2.2e-20 73.1 0.0 6.5e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PXF46780.1 - 5.4e-06 26.1 0.0 5.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 PXF46780.1 - 2.3e-05 24.5 0.0 0.076 13.1 0.0 3.3 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 PXF46780.1 - 0.0032 17.1 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PXF46780.1 - 0.02 14.4 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Methyltransf_3 PF01596.17 PXF46781.1 - 7.4e-46 156.0 0.1 1.2e-45 155.3 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase DHQ_synthase PF01761.20 PXF46781.1 - 1.5e-42 145.6 0.0 1.7e-41 142.1 0.0 2.1 2 0 0 2 2 2 1 3-dehydroquinate synthase Methyltransf_24 PF13578.6 PXF46781.1 - 5e-12 46.8 0.1 1.3e-11 45.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF46781.1 - 8.8e-06 25.6 0.1 2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF46781.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 PXF46781.1 - 1.5e-05 24.9 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PXF46781.1 - 2.7e-05 24.8 0.1 7.9e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PXF46781.1 - 0.017 14.8 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MtmB PF05369.12 PXF46781.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB MFS_1 PF07690.16 PXF46782.1 - 1.3e-27 96.7 31.2 1.3e-27 96.7 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Inositol_P PF00459.25 PXF46783.1 - 2.1e-57 194.7 0.1 2.5e-57 194.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PA26 PF04636.13 PXF46784.1 - 0.21 10.5 1.1 0.29 10.0 1.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_C48 PF02902.19 PXF46785.1 - 6.4e-34 117.7 2.0 1.5e-31 110.0 1.2 2.2 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Taxilin PF09728.9 PXF46785.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein XPG_N PF00752.17 PXF46786.1 - 3e-29 101.5 0.0 1e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 PXF46786.1 - 2.8e-26 91.7 2.1 2.9e-26 91.6 0.0 2.2 2 1 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 PXF46786.1 - 6.8e-05 23.4 0.0 0.00021 21.8 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold WD40 PF00400.32 PXF46787.1 - 4.8e-29 100.0 16.1 2.3e-06 28.2 0.0 8.7 10 0 0 10 10 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46787.1 - 1.1e-19 70.5 0.2 1.8e-06 28.1 0.0 6.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PXF46787.1 - 2.1e-14 53.7 0.1 3.5e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 PXF46787.1 - 3.1e-10 39.5 0.4 0.0002 20.4 0.0 4.7 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PXF46787.1 - 2.6e-09 37.2 0.1 4.4e-06 26.7 0.0 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PXF46787.1 - 6.4e-05 22.8 0.0 0.095 12.7 0.1 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PXF46787.1 - 0.0035 16.1 0.8 0.043 12.5 0.0 3.1 3 1 1 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 PXF46787.1 - 0.039 13.3 0.0 1.3 8.3 0.0 2.9 4 0 0 4 4 4 0 WD40-like domain DUF1513 PF07433.11 PXF46787.1 - 0.057 12.5 2.5 0.66 9.0 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1513) TFIIIC_delta PF12657.7 PXF46787.1 - 0.062 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term TruB_C PF09142.11 PXF46787.1 - 0.22 11.3 2.7 33 4.4 0.1 4.0 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal HemolysinCabind PF00353.19 PXF46789.1 - 1.1e-16 60.4 40.7 5.8e-09 35.8 5.4 7.1 7 0 0 7 7 7 5 RTX calcium-binding nonapeptide repeat (4 copies) Com_YlbF PF06133.11 PXF46789.1 - 0.13 12.9 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA TPR_1 PF00515.28 PXF46790.1 - 4.5e-13 48.4 5.8 3e-05 23.7 0.9 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46790.1 - 2.4e-10 39.9 0.8 1.2e-06 28.1 1.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 PXF46790.1 - 2.2e-07 30.5 2.6 0.00058 19.8 0.5 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF46790.1 - 6.8e-05 23.1 6.4 0.0057 16.9 1.9 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46790.1 - 0.00061 19.8 1.0 11 6.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF46790.1 - 0.0065 16.8 1.9 3 8.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46790.1 - 0.0069 17.1 9.5 0.081 13.8 1.3 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 PXF46790.1 - 0.045 13.2 1.6 0.091 12.2 0.1 2.1 2 1 1 3 3 3 0 Coatomer epsilon subunit MIT PF04212.18 PXF46790.1 - 0.097 12.8 2.5 0.31 11.1 1.6 2.3 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 PXF46790.1 - 1 10.0 5.3 0.56 10.8 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 PXF46790.1 - 2.2 8.2 13.3 16 5.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FMO-like PF00743.19 PXF46791.1 - 0.018 13.5 0.3 0.021 13.2 0.3 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like PH_16 PF17838.1 PXF46793.1 - 0.0098 15.7 0.0 0.027 14.3 0.0 1.7 2 0 0 2 2 2 1 PH domain SSURE PF11966.8 PXF46795.1 - 0.00079 19.1 3.5 14 5.5 0.0 5.7 2 1 6 8 8 8 2 Fibronectin-binding repeat Toxin_38 PF14866.6 PXF46795.1 - 0.51 10.7 28.1 10 6.5 0.1 7.2 8 0 0 8 8 8 0 Potassium channel toxin CTD PF12815.7 PXF46796.1 - 0.044 14.3 0.3 0.15 12.6 0.3 1.9 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Nucleoporin_FG PF13634.6 PXF46796.1 - 4 8.3 43.7 23 5.9 43.7 2.0 1 1 0 1 1 1 0 Nucleoporin FG repeat region DEC-1_C PF04626.13 PXF46796.1 - 9 6.7 6.7 0.89 10.0 1.7 1.8 1 1 0 2 2 2 0 Dec-1 protein, C terminal region M60-like_N PF17291.2 PXF46799.1 - 0.0054 16.6 0.0 0.0069 16.3 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases UBX PF00789.20 PXF46801.1 - 0.00021 21.4 0.0 0.00038 20.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain TPM_phosphatase PF04536.14 PXF46802.1 - 4.7e-05 23.5 0.0 6.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 TPM domain Pox_A_type_inc PF04508.12 PXF46802.1 - 0.0013 18.5 0.7 0.021 14.7 0.2 2.3 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat ATP-grasp_2 PF08442.10 PXF46803.1 - 1.1e-66 224.2 0.2 2.6e-66 223.0 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 PXF46803.1 - 1.3e-25 90.0 2.5 1.3e-25 90.0 2.5 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 PXF46803.1 - 2.2e-07 30.6 0.8 1.1e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 PXF46803.1 - 0.0003 20.6 1.0 0.0013 18.6 0.6 2.3 2 1 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain GARS_A PF01071.19 PXF46803.1 - 0.00088 19.1 0.1 0.0029 17.4 0.1 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PASTA PF03793.19 PXF46803.1 - 0.003 17.4 0.1 1 9.3 0.0 2.8 2 0 0 2 2 2 2 PASTA domain HHH_5 PF14520.6 PXF46803.1 - 0.026 15.1 0.2 0.35 11.5 0.1 2.7 1 1 1 2 2 2 0 Helix-hairpin-helix domain Nup88 PF10168.9 PXF46805.1 - 0.0016 16.3 2.3 0.0021 16.0 2.3 1.1 1 0 0 1 1 1 1 Nuclear pore component bZIP_Maf PF03131.17 PXF46805.1 - 0.019 15.5 7.5 0.019 15.5 7.5 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF1043 PF06295.12 PXF46805.1 - 0.028 14.4 2.7 0.043 13.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) T2SSF PF00482.23 PXF46805.1 - 0.07 13.1 1.4 0.1 12.6 1.4 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F bZIP_1 PF00170.21 PXF46805.1 - 0.54 10.4 13.6 1.5 9.0 13.0 2.0 1 1 2 3 3 3 0 bZIP transcription factor HisKA_3 PF07730.13 PXF46805.1 - 0.7 10.4 5.2 1.5 9.3 1.6 2.4 1 1 1 2 2 2 0 Histidine kinase V_ATPase_I PF01496.19 PXF46805.1 - 0.79 7.6 3.8 0.92 7.3 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 PXF46805.1 - 1.6 7.3 4.2 1.8 7.1 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cue1_U7BR PF18499.1 PXF46805.1 - 9.4 6.4 8.1 0.31 11.1 0.4 2.4 3 0 0 3 3 3 0 Ubc7p-binding region of Cue1 bZIP_1 PF00170.21 PXF46806.1 - 1.1e-10 41.5 11.6 1.1e-10 41.5 11.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF46806.1 - 1.2e-05 25.3 11.4 1.2e-05 25.3 11.4 2.2 2 0 0 2 2 2 1 Basic region leucine zipper SfsA PF03749.13 PXF46806.1 - 0.11 12.4 0.4 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain SlyX PF04102.12 PXF46806.1 - 5.6 7.7 8.4 1.6 9.4 2.3 2.6 1 1 1 2 2 2 0 SlyX Cyclin_N PF00134.23 PXF46807.1 - 1.5e-12 47.4 0.1 2.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1_dh PF00676.20 PXF46808.1 - 1.4e-105 352.6 0.1 1.6e-105 352.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PXF46808.1 - 0.022 14.0 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase F-box-like PF12937.7 PXF46810.1 - 2.7e-07 30.4 0.2 2.7e-07 30.4 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 PXF46810.1 - 0.00017 21.4 0.1 0.00029 20.7 0.1 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 PXF46810.1 - 0.0091 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Glyco_transf_5 PF08323.11 PXF46811.1 - 2.1e-32 112.8 0.0 4.4e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 PXF46811.1 - 2.1e-19 69.5 0.1 4.9e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 PXF46811.1 - 7.2e-13 48.4 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF46811.1 - 5.8e-07 30.0 0.0 1.8e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 CBM_48 PF02922.18 PXF46811.1 - 0.0041 17.4 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_transf_4 PF13439.6 PXF46811.1 - 0.0051 16.8 0.2 0.028 14.4 0.2 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PXF46811.1 - 0.013 15.9 0.0 0.1 13.0 0.0 2.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain TnsD PF15978.5 PXF46811.1 - 0.13 11.2 0.2 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 Tn7-like transposition protein D zf-CCCH_4 PF18044.1 PXF46812.1 - 1.3e-09 37.7 3.2 2.3e-09 36.8 3.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PXF46812.1 - 2.2e-07 30.7 7.1 3.7e-07 30.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PXF46812.1 - 6.4e-07 29.1 1.9 1.1e-06 28.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PXF46812.1 - 0.039 14.7 0.3 0.081 13.6 0.3 1.5 1 0 0 1 1 1 0 Torus domain Sld5 PF05916.11 PXF46813.1 - 1.3e-19 70.7 1.2 2e-19 70.0 1.2 1.3 1 0 0 1 1 1 1 GINS complex protein MPC PF03650.13 PXF46814.1 - 4.7e-37 126.5 0.2 4.9e-37 126.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 PXF46814.1 - 0.081 13.0 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DnaJ_C PF01556.18 PXF46816.1 - 9.5e-39 132.8 0.1 1.6e-38 132.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF46816.1 - 7.2e-23 80.5 0.2 1.2e-22 79.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PXF46816.1 - 1.9e-14 53.7 13.6 3.3e-14 53.0 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PXF46816.1 - 0.00015 21.7 5.1 0.025 14.5 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PXF46816.1 - 0.012 15.6 4.8 1.3 9.0 1.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 PXF46816.1 - 0.42 10.3 5.0 2.2 7.9 2.1 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 PXF46816.1 - 2.4 8.2 6.7 5.1 7.2 0.8 2.4 1 1 0 2 2 2 0 zinc-ribbons Integrase_H2C2 PF17921.1 PXF46816.1 - 7.9 6.7 5.7 8.5 6.6 0.0 2.7 3 0 0 3 3 3 0 Integrase zinc binding domain Prp19 PF08606.11 PXF46817.1 - 5.4e-18 64.7 1.1 1e-17 63.9 1.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 PXF46817.1 - 3.5e-05 24.5 7.5 0.0057 17.5 0.6 4.2 4 1 0 4 4 4 2 WD domain, G-beta repeat U-box PF04564.15 PXF46817.1 - 0.00057 20.0 0.0 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 PXF46817.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TSNAXIP1_N PF15739.5 PXF46817.1 - 0.083 13.3 0.4 0.083 13.3 0.4 1.9 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Rtf2 PF04641.12 PXF46817.1 - 0.15 11.4 6.5 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger GAS PF13851.6 PXF46817.1 - 7.1 5.9 14.4 0.043 13.1 1.9 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 PXF46818.1 - 0.004 17.4 2.8 0.004 17.4 2.8 2.8 3 0 0 3 3 3 1 Homeobox associated leucine zipper YabA PF06156.13 PXF46818.1 - 0.005 17.4 0.4 0.005 17.4 0.4 2.5 2 1 0 2 2 2 1 Initiation control protein YabA Ndc1_Nup PF09531.10 PXF46818.1 - 0.047 12.4 7.2 0.062 12.0 7.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIN_12 PF16289.5 PXF46818.1 - 0.29 11.6 8.6 0.51 10.8 4.9 2.6 3 0 0 3 3 3 0 PIN domain Cwf_Cwc_15 PF04889.12 PXF46818.1 - 1.7 8.3 22.6 2.6 7.7 22.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 PXF46818.1 - 2.2 7.0 10.5 3.5 6.3 10.5 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NAC PF01849.18 PXF46819.1 - 1.6e-20 72.8 0.9 3.3e-20 71.8 0.1 1.9 2 0 0 2 2 2 1 NAC domain PDH PF02153.17 PXF46820.1 - 5.2e-16 58.4 0.0 7.4e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 PXF46820.1 - 1.1e-06 29.1 0.0 2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PXF46820.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 PXF46820.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.15 PXF46820.1 - 0.056 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase C4bp_oligo PF18453.1 PXF46820.1 - 0.1 12.8 0.4 16 5.8 0.0 2.6 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha NAD_Gly3P_dh_N PF01210.23 PXF46820.1 - 0.1 12.6 0.1 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Transket_pyr PF02779.24 PXF46821.1 - 2.9e-44 150.9 0.0 4.2e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PXF46821.1 - 1.9e-40 137.6 0.0 4.6e-40 136.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 PXF46821.1 - 0.0009 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II PHBC_N PF12551.8 PXF46821.1 - 0.33 10.8 3.4 4.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal Hydrolase_3 PF08282.12 PXF46822.1 - 4.8e-47 160.9 0.0 5.6e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PXF46822.1 - 1.5e-10 41.1 0.0 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PXF46822.1 - 0.00014 22.2 0.2 0.0072 16.6 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF46822.1 - 0.00042 20.8 0.0 1.8 8.9 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 PXF46822.1 - 0.015 14.4 0.0 0.034 13.3 0.0 1.5 2 0 0 2 2 2 0 Trehalose-phosphatase HAD_2 PF13419.6 PXF46822.1 - 0.11 12.6 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase YabA PF06156.13 PXF46823.1 - 0.078 13.6 0.8 0.18 12.5 0.8 1.6 1 0 0 1 1 1 0 Initiation control protein YabA SNF2_N PF00176.23 PXF46824.1 - 1.5e-62 211.3 0.0 3.4e-62 210.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF46824.1 - 1.1e-17 64.4 0.0 5.2e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF46824.1 - 2.2e-07 31.0 0.0 8.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.17 PXF46825.1 - 1e-50 172.5 0.0 4.2e-50 170.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF46825.1 - 3e-43 148.1 0.0 6.1e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PXF46825.1 - 2.6e-31 108.1 0.0 3.2e-12 46.9 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF46825.1 - 2.2e-23 82.3 0.2 6e-10 39.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PXF46825.1 - 2e-16 59.8 1.3 1.5e-09 37.9 0.0 4.0 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF46825.1 - 2.4e-16 58.1 0.1 1.5e-06 28.1 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PXF46825.1 - 4e-16 58.6 0.0 4.4e-08 33.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Pkinase_fungal PF17667.1 PXF46825.1 - 0.0017 17.2 0.0 0.0044 15.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PXF46825.1 - 0.034 13.1 0.0 0.096 11.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Flt3_lig PF02947.14 PXF46825.1 - 0.069 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 flt3 ligand Josephin PF02099.17 PXF46826.1 - 2.6e-05 24.4 0.5 0.00064 19.9 0.0 2.1 1 1 1 2 2 2 2 Josephin zf-C2H2 PF00096.26 PXF46827.1 - 1.4e-14 53.6 23.4 9.8e-05 22.6 2.1 4.8 4 1 1 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF46827.1 - 5.1e-13 48.7 21.9 0.00058 20.5 1.6 4.7 4 1 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF46827.1 - 0.00024 21.3 12.9 0.1 12.9 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 PXF46827.1 - 0.00035 20.9 3.5 0.00035 20.9 3.5 5.3 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 PXF46827.1 - 0.0006 20.5 5.0 0.014 16.1 0.0 2.9 3 1 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 PXF46827.1 - 0.0033 17.2 2.0 0.083 12.7 0.1 4.3 4 1 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 PXF46827.1 - 0.0082 16.5 17.9 0.3 11.4 0.9 4.0 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PXF46827.1 - 0.05 14.0 9.3 0.31 11.5 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-BED PF02892.15 PXF46827.1 - 0.067 13.2 0.3 0.067 13.2 0.3 4.5 4 1 1 5 5 5 0 BED zinc finger zf-C2H2_9 PF16293.5 PXF46827.1 - 0.14 12.1 6.8 0.64 9.9 0.8 3.3 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 PXF46827.1 - 0.15 12.1 9.2 0.8 9.8 4.6 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 PXF46827.1 - 0.29 11.7 7.5 1.3 9.6 4.8 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 PXF46827.1 - 0.31 11.0 16.3 2.8 7.9 5.7 4.4 4 1 0 4 4 4 0 SprT-like zinc ribbon domain Rpr2 PF04032.16 PXF46827.1 - 0.33 11.3 5.8 0.28 11.5 3.6 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TALPID3 PF15324.6 PXF46827.1 - 0.87 7.2 8.7 1.1 6.9 8.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zinc-ribbons_6 PF07191.12 PXF46827.1 - 2.2 8.3 9.0 15 5.6 3.5 3.5 2 1 1 3 3 3 0 zinc-ribbons PyrI_C PF02748.15 PXF46827.1 - 3.1 7.8 10.5 6.1 6.8 0.2 3.9 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.12 PXF46827.1 - 3.2 8.1 8.5 31 4.9 0.1 3.3 2 1 2 4 4 4 0 TFIIH C1-like domain Desulfoferrod_N PF06397.12 PXF46827.1 - 6.5 6.5 9.7 23 4.7 0.0 3.4 4 0 0 4 4 3 0 Desulfoferrodoxin, N-terminal domain FOXP-CC PF16159.5 PXF46827.1 - 7.8 7.2 9.6 12 6.6 0.2 3.6 2 1 0 3 3 3 0 FOXP coiled-coil domain NMT PF01233.19 PXF46828.1 - 7.6e-73 243.6 0.0 1.1e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 PXF46828.1 - 1.2e-68 230.8 0.1 2e-68 230.0 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 PXF46828.1 - 7.7e-05 22.8 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF46828.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Aldo_ket_red PF00248.21 PXF46829.1 - 7.3e-65 219.1 0.0 8.4e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SAM_Exu PF18609.1 PXF46829.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Exuperantia SAM-like domain ABC1 PF03109.16 PXF46831.1 - 2.1e-34 118.2 0.0 5.2e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PXF46831.1 - 0.00022 20.7 0.0 0.0036 16.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF46831.1 - 0.0029 17.6 5.2 0.024 14.6 0.0 3.9 4 1 0 4 4 4 1 Phosphotransferase enzyme family PSCyt3 PF07627.11 PXF46831.1 - 0.065 13.5 1.3 0.17 12.2 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Sec23_helical PF04815.15 PXF46831.1 - 0.13 12.1 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Sec23/Sec24 helical domain 2-Hacid_dh_C PF02826.19 PXF46832.1 - 3.2e-59 199.3 0.0 5.9e-59 198.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PXF46832.1 - 6.8e-35 119.7 0.1 1.4e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 PXF46832.1 - 6.1e-05 22.7 0.4 0.00043 20.0 0.0 2.6 3 0 0 3 3 3 1 ACT domain NAD_binding_2 PF03446.15 PXF46832.1 - 0.00014 22.1 0.8 0.0025 18.0 0.1 2.8 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PXF46832.1 - 0.0015 18.6 0.1 0.005 16.9 0.1 1.8 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PXF46832.1 - 0.0033 17.0 0.0 0.008 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 PXF46832.1 - 0.013 16.1 0.7 0.089 13.4 0.1 2.7 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 PXF46832.1 - 0.049 13.9 0.0 0.9 9.8 0.0 2.9 2 0 0 2 2 2 0 TrkA-N domain WBS_methylT PF12589.8 PXF46833.1 - 3e-13 50.3 3.0 4.7e-13 49.7 3.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 PXF46833.1 - 2.2e-08 34.6 0.1 4.3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF46833.1 - 6.8e-08 33.1 0.1 1.3e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF46833.1 - 0.00021 22.0 0.1 0.0005 20.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF46833.1 - 0.017 14.9 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 PXF46833.1 - 0.16 11.2 0.0 7.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 MttA_Hcf106 PF02416.16 PXF46834.1 - 9.4e-06 24.9 0.1 1.7e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 mttA/Hcf106 family Pex2_Pex12 PF04757.14 PXF46835.1 - 3.1e-28 98.9 10.8 4.8e-28 98.3 10.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 PXF46835.1 - 6.1e-05 22.8 8.1 0.0001 22.0 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF46835.1 - 8.3e-05 22.4 5.3 0.00015 21.5 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF46835.1 - 0.0027 18.0 6.4 0.0045 17.3 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF46835.1 - 0.0089 16.0 9.6 0.016 15.2 9.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF46835.1 - 0.013 15.4 8.5 0.021 14.7 8.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46835.1 - 0.18 12.1 3.5 0.34 11.2 3.5 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 PXF46835.1 - 0.27 11.1 3.4 0.56 10.1 3.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 PXF46835.1 - 3.2 8.0 7.2 5.5 7.2 7.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PXF46835.1 - 7.6 6.6 8.4 13 5.9 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sulfotransfer_2 PF03567.14 PXF46836.1 - 7.3e-10 39.2 2.5 6.4e-08 32.8 0.1 2.1 2 0 0 2 2 2 2 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 PXF46836.1 - 0.016 14.1 0.7 0.075 11.9 0.7 1.9 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase Baculo_LEF-2 PF03041.14 PXF46836.1 - 0.047 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 lef-2 Sulfotransfer_1 PF00685.27 PXF46836.1 - 0.049 13.1 0.7 0.18 11.2 0.0 2.0 2 1 0 2 2 2 0 Sulfotransferase domain Lactamase_B_2 PF12706.7 PXF46837.1 - 0.00011 21.9 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF46837.1 - 0.099 12.6 0.7 0.2 11.6 0.7 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 PXF46838.1 - 0.0048 16.0 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 PXF46838.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF46838.1 - 0.16 12.0 1.3 0.58 10.1 1.3 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily PAN_3 PF08277.12 PXF46840.1 - 0.0035 17.1 0.5 0.01 15.6 0.3 1.8 2 0 0 2 2 2 1 PAN-like domain Lactamase_B_2 PF12706.7 PXF46840.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PDEase_II PF02112.15 PXF46840.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 PXF46840.1 - 0.18 11.8 0.6 0.77 9.7 0.4 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Amidohydro_1 PF01979.20 PXF46842.1 - 1.5e-15 57.3 0.1 2.1e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Nucleopor_Nup85 PF07575.13 PXF46842.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF2573 PF10835.8 PXF46843.1 - 0.02 15.2 0.0 0.021 15.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) FMO-like PF00743.19 PXF46845.1 - 4.4e-33 114.5 0.0 2.2e-19 69.3 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PXF46845.1 - 7.4e-13 48.4 0.1 3e-06 26.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF46845.1 - 4.2e-11 43.1 0.3 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 PXF46845.1 - 6.9e-11 41.9 0.1 6.2e-09 35.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PXF46845.1 - 6.4e-09 35.4 0.6 2.8e-08 33.3 0.1 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PXF46845.1 - 2.3e-08 34.1 1.2 3.5e-07 30.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PXF46845.1 - 1.7e-05 25.3 1.6 0.053 14.1 0.0 2.9 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF46845.1 - 0.00017 20.4 0.3 0.0005 18.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 PXF46845.1 - 0.00019 20.8 0.2 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 PXF46845.1 - 0.0003 20.5 5.9 0.052 13.1 0.5 3.9 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PXF46845.1 - 0.0003 20.2 2.4 0.0016 17.8 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 PXF46845.1 - 0.0019 17.6 0.9 0.0059 16.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF46845.1 - 0.007 15.5 1.3 0.0098 15.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 PXF46845.1 - 0.025 13.9 1.2 2.1 7.5 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 PXF46845.1 - 0.042 12.9 1.9 1.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PXF46845.1 - 0.37 9.8 2.5 1.5 7.8 0.4 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PXF46845.1 - 0.51 9.6 2.5 0.27 10.5 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MnmE_helical PF12631.7 PXF46846.1 - 2.2e-49 168.4 0.7 2.9e-49 168.1 0.7 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 PXF46846.1 - 1.1e-36 125.7 0.0 6.9e-36 123.1 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 PXF46846.1 - 1.3e-21 76.7 0.0 3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF46846.1 - 2.8e-08 33.4 0.2 1.6e-07 31.0 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PXF46846.1 - 1.2e-06 28.7 0.0 3.2e-06 27.3 0.0 1.8 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 PXF46846.1 - 1.9e-05 24.7 0.0 0.31 11.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 PXF46846.1 - 0.00026 21.5 0.0 0.00092 19.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Arf PF00025.21 PXF46846.1 - 0.00054 19.5 0.1 0.071 12.5 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family MeaB PF03308.16 PXF46846.1 - 0.00084 18.4 0.2 1.3 7.9 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 PXF46846.1 - 0.00094 18.8 1.4 1.4 8.4 0.6 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 PXF46846.1 - 0.0018 18.5 0.0 0.0041 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.16 PXF46846.1 - 0.0037 16.6 0.0 0.0079 15.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_29 PF13555.6 PXF46846.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 PXF46846.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF46846.1 - 0.05 14.0 1.1 0.2 12.0 0.4 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 PXF46846.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 PXF46846.1 - 0.17 11.5 0.0 0.44 10.1 0.0 1.7 1 1 0 1 1 1 0 Ras family Acetyltransf_1 PF00583.25 PXF46847.1 - 4.1e-12 46.4 0.0 5.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF46847.1 - 8.6e-08 32.5 0.0 1.7e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF46847.1 - 1.2e-06 28.4 0.0 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF46847.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 PXF46847.1 - 0.0021 17.5 0.1 0.0026 17.3 0.1 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Gly_acyl_tr_C PF08444.10 PXF46847.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Cyclin PF08613.11 PXF46848.1 - 4.4e-27 95.4 0.5 4.4e-27 95.4 0.5 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PXF46848.1 - 1.3e-08 34.6 0.5 2.3e-08 33.8 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Thoc2 PF11732.8 PXF46848.1 - 0.06 13.4 0.3 4.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Transcription- and export-related complex subunit RNA_pol_Rpb1_5 PF04998.17 PXF46849.1 - 3.2e-104 348.1 0.0 4.9e-104 347.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PXF46849.1 - 3.4e-94 315.7 0.0 5.2e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PXF46849.1 - 9.2e-77 256.9 0.8 2.7e-76 255.4 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PXF46849.1 - 6.6e-52 176.1 0.2 1.2e-51 175.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 PXF46849.1 - 1.6e-49 167.9 0.0 2.8e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 PXF46849.1 - 1.1e-37 129.1 1.7 2.4e-37 128.0 1.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 PXF46849.1 - 7.3e-35 119.2 0.1 1.8e-34 117.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CCER1 PF15482.6 PXF46850.1 - 0.055 13.4 0.0 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Doppel PF11466.8 PXF46850.1 - 0.075 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel TAF4 PF05236.14 PXF46851.1 - 7.3e-15 55.4 13.9 3.2e-14 53.3 13.9 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 PXF46851.1 - 0.0066 16.2 0.4 0.0066 16.2 0.4 3.7 3 1 1 4 4 4 1 Transcriptional regulator of RNA polII, SAGA, subunit ETC_C1_NDUFA4 PF04800.12 PXF46852.1 - 3.1e-28 97.9 0.0 4.1e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 PXF46852.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) YlqD PF11068.8 PXF46853.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 YlqD protein Nmad3 PF18754.1 PXF46854.1 - 0.0071 15.9 0.1 0.0095 15.5 0.1 1.3 1 0 0 1 1 1 1 Nucleotide modification associated domain 3 Retrotran_gag_2 PF14223.6 PXF46855.1 - 1.7e-13 50.4 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDE_1 PF03184.19 PXF46856.1 - 9e-13 48.2 0.0 2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 PXF46856.1 - 0.043 13.6 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 DDE superfamily endonuclease WASH-7_C PF14746.6 PXF46856.1 - 0.33 10.6 1.3 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal TAF4 PF05236.14 PXF46857.1 - 2.2e-17 63.7 7.9 9.5e-17 61.6 7.9 2.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 PXF46857.1 - 0.006 16.4 0.1 0.006 16.4 0.1 3.5 2 2 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit ETC_C1_NDUFA4 PF04800.12 PXF46858.1 - 1.1e-27 96.1 0.0 1.5e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region SQS_PSY PF00494.19 PXF46860.1 - 1.1e-68 231.6 0.7 1.5e-68 231.2 0.7 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DnaJ_CXXCXGXG PF00684.19 PXF46861.1 - 8.6e-05 22.8 15.0 0.023 15.0 7.5 3.0 1 1 1 2 2 2 2 DnaJ central domain RecR PF02132.15 PXF46861.1 - 0.043 13.4 2.4 0.043 13.4 2.4 2.4 3 0 0 3 3 3 0 RecR protein Anti-TRAP PF15777.5 PXF46861.1 - 2.6 8.1 13.9 17 5.5 7.4 3.1 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 PXF46861.1 - 8.8 6.6 18.2 2.4 8.4 1.0 4.1 2 2 2 4 4 4 0 Family of unknown function (DUF5351) 2OG-FeII_Oxy PF03171.20 PXF46863.1 - 7e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 PXF46863.1 - 6.6e-14 52.7 0.0 1.4e-13 51.7 0.0 1.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal zf_ZIC PF18366.1 PXF46863.1 - 0.069 13.3 1.8 3.5 7.8 0.1 2.5 1 1 1 2 2 2 0 Zic proteins zinc finger domain eIF2A PF08662.11 PXF46864.1 - 1e-66 224.5 0.0 4.9e-66 222.3 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DFRP_C PF16543.5 PXF46865.1 - 3.9e-18 65.7 4.1 3.9e-18 65.7 4.1 2.9 2 2 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Reprolysin PF01421.19 PXF46865.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease WD40 PF00400.32 PXF46866.1 - 1.1e-05 26.1 11.9 0.026 15.4 0.2 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46866.1 - 0.0096 16.2 0.0 0.15 12.4 0.0 3.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IL2 PF00715.17 PXF46867.1 - 0.064 13.2 0.5 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Interleukin 2 Sep15_SelM PF08806.11 PXF46867.1 - 0.68 10.1 3.7 4.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Sep15/SelM redox domain SLD5_C PF16922.5 PXF46868.1 - 1.7e-13 50.5 0.0 4.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus ApoB100_C PF12491.8 PXF46868.1 - 0.017 15.1 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Sld5 PF05916.11 PXF46868.1 - 0.02 15.3 1.6 0.04 14.4 1.6 1.6 1 1 0 1 1 1 0 GINS complex protein DFP PF04127.15 PXF46869.1 - 6.8e-16 58.6 0.0 1.2e-10 41.5 0.0 2.2 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Diphthamide_syn PF01866.17 PXF46870.1 - 8.2e-67 225.8 0.8 5.4e-65 219.8 0.8 2.1 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CRAL_TRIO PF00650.20 PXF46871.1 - 9e-28 97.0 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PXF46871.1 - 0.0054 16.9 0.0 0.009 16.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PXF46871.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain RRM_1 PF00076.22 PXF46872.1 - 1.8e-17 62.9 0.0 3.4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF46872.1 - 0.00097 19.2 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 PXF46872.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Methyltransf_33 PF10017.9 PXF46873.1 - 1.7e-88 296.7 0.0 2.1e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SelB-wing_3 PF09107.11 PXF46873.1 - 0.0066 16.1 0.0 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 Elongation factor SelB, winged helix Methyltransf_25 PF13649.6 PXF46873.1 - 0.11 13.2 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Vinculin PF01044.19 PXF46873.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Vinculin family WD40 PF00400.32 PXF46874.1 - 4.3e-34 116.0 0.0 9.4e-06 26.3 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46874.1 - 9e-12 45.1 0.0 0.00041 20.6 0.0 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 PXF46874.1 - 2.9e-05 23.8 0.1 0.59 9.7 0.0 3.1 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 PXF46874.1 - 4.4e-05 22.6 0.0 0.17 10.8 0.0 3.6 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PXF46874.1 - 0.00031 20.7 0.1 0.064 13.1 0.0 3.1 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 PXF46874.1 - 0.0052 16.4 0.1 4.1 6.9 0.0 2.7 3 0 0 3 3 3 2 PQQ-like domain Fer2 PF00111.27 PXF46875.1 - 9.9e-12 44.7 0.5 1.5e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-RING_2 PF13639.6 PXF46876.1 - 6.2e-08 32.9 10.3 1.8e-07 31.4 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF46876.1 - 0.00013 21.9 3.5 0.00065 19.7 1.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 PXF46876.1 - 0.001 18.8 5.0 0.001 18.8 5.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF46876.1 - 0.0011 18.8 8.9 0.0023 17.7 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PXF46876.1 - 0.006 16.7 2.7 0.006 16.7 2.7 2.1 1 1 1 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.6 PXF46876.1 - 0.0061 16.5 9.3 0.012 15.6 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PXF46876.1 - 0.022 14.6 10.3 0.047 13.6 10.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF46876.1 - 0.031 14.6 11.4 0.031 14.6 11.4 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 PXF46876.1 - 0.052 13.2 9.0 0.11 12.1 9.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PXF46876.1 - 0.052 13.4 7.9 0.11 12.3 7.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PXF46876.1 - 1.5 9.0 12.5 4 7.7 12.5 1.8 1 0 0 1 1 1 0 RING-variant domain Pkinase PF00069.25 PXF46877.1 - 2.5e-61 207.3 0.0 3.7e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46877.1 - 8.9e-41 139.9 0.0 4.4e-40 137.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF46877.1 - 1.2e-07 30.9 0.0 1.2e-07 30.9 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 PXF46877.1 - 0.0056 16.0 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF46877.1 - 0.027 13.8 0.2 0.052 12.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP_fibrillin PF04755.12 PXF46878.1 - 3.9e-29 102.0 0.2 3.2e-27 95.8 0.2 2.1 1 1 0 1 1 1 1 PAP_fibrillin DUF489 PF04356.12 PXF46878.1 - 0.18 11.8 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) zf-C2H2_4 PF13894.6 PXF46882.1 - 2.4e-06 27.9 5.6 0.00035 21.2 1.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF46882.1 - 0.00051 19.7 4.2 0.067 13.0 0.6 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 PXF46882.1 - 0.0013 19.1 5.2 0.02 15.3 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-LYAR PF08790.11 PXF46882.1 - 0.014 15.2 3.9 0.055 13.4 1.0 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 PXF46882.1 - 0.018 15.1 9.5 0.13 12.3 3.4 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF46882.1 - 0.044 14.1 3.8 3.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 PXF46882.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.9 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Yip1 PF04893.17 PXF46883.1 - 5.4e-14 52.3 17.8 9.7e-14 51.5 17.7 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 PXF46883.1 - 0.48 10.2 14.9 0.39 10.5 13.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 PXF46883.1 - 6 5.0 9.5 7.6 4.7 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMP-TENI PF02581.17 PXF46884.1 - 5.9e-26 90.9 0.1 1.1e-25 90.1 0.1 1.4 1 1 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 PXF46884.1 - 0.046 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Imm39 PF15568.6 PXF46884.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 Thiolase_N PF00108.23 PXF46885.1 - 5e-67 226.0 0.4 9.2e-67 225.1 0.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PXF46885.1 - 4.7e-46 155.4 0.5 1.1e-45 154.2 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain 3HCDH_N PF02737.18 PXF46885.1 - 5.4e-46 156.7 0.3 1.3e-45 155.5 0.3 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 PXF46885.1 - 4.1e-43 147.5 0.1 8.2e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 PXF46885.1 - 7.1e-25 87.4 0.1 2.6e-21 76.0 0.0 3.2 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 PXF46885.1 - 3.4e-21 76.1 0.0 8.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 PXF46885.1 - 0.0013 18.3 0.2 0.0042 16.7 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_2 PF03446.15 PXF46885.1 - 0.0024 18.1 0.2 0.0049 17.0 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 PXF46885.1 - 0.014 15.9 0.5 0.048 14.2 0.5 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF46885.1 - 0.028 13.7 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 PXF46885.1 - 0.03 14.9 3.2 0.034 14.7 0.8 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 PXF46885.1 - 0.24 10.7 2.7 0.19 11.0 0.8 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Borrelia_P13 PF05628.12 PXF46885.1 - 0.49 10.4 2.2 0.42 10.6 0.4 1.8 2 0 0 2 2 2 0 Borrelia membrane protein P13 DUF1192 PF06698.11 PXF46886.1 - 0.0031 17.5 3.1 0.0063 16.5 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 PXF46886.1 - 0.018 15.2 5.7 0.018 15.2 5.7 1.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain CCDC92 PF14916.6 PXF46886.1 - 0.027 14.2 1.5 0.045 13.5 1.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function COG5 PF10392.9 PXF46886.1 - 0.11 12.6 2.1 0.24 11.6 2.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ING PF12998.7 PXF46886.1 - 0.11 13.0 1.7 0.17 12.5 1.3 1.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ACCA PF03255.14 PXF46886.1 - 0.73 9.7 3.7 1.2 9.0 3.7 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit POP1 PF06978.11 PXF46886.1 - 1.6 8.7 7.0 0.75 9.7 0.7 2.0 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 SMC_N PF02463.19 PXF46887.1 - 1.6e-61 207.5 23.5 5e-61 205.9 23.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PXF46887.1 - 3.8e-24 85.3 0.1 1.5e-23 83.4 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 PXF46887.1 - 2.5e-14 54.3 7.1 2.5e-14 54.3 7.1 6.2 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 PXF46887.1 - 2.9e-09 37.2 14.0 0.00018 21.5 0.2 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PXF46887.1 - 0.00026 20.7 0.0 0.00065 19.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 PXF46887.1 - 0.011 15.7 1.6 0.011 15.7 1.6 4.4 3 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 PXF46887.1 - 1.1 9.8 30.5 1.1 9.8 4.3 6.3 3 2 1 4 4 4 0 ABC transporter CitMHS PF03600.16 PXF46888.1 - 2e-27 96.2 23.7 2e-27 96.2 23.7 2.2 1 1 1 2 2 2 2 Citrate transporter Mito_carr PF00153.27 PXF46889.1 - 2.4e-51 171.6 1.7 1.2e-21 76.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Adap_comp_sub PF00928.21 PXF46891.1 - 2.4e-86 289.4 0.0 3e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PXF46891.1 - 1.9e-08 34.4 2.1 3.1e-08 33.7 2.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 PXF46891.1 - 0.058 12.5 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 DehI PF10778.9 PXF46892.1 - 0.039 14.1 1.0 0.055 13.6 1.0 1.2 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Antimicrobial_7 PF08102.11 PXF46892.1 - 0.21 11.8 0.8 1.6 9.0 0.4 2.2 1 1 1 2 2 2 0 Scorpion antimicrobial peptide DEAD_2 PF06733.15 PXF46893.1 - 5.9e-45 153.0 0.1 9.4e-45 152.4 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 PXF46893.1 - 4.1e-43 147.5 0.1 9.4e-43 146.3 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 PXF46893.1 - 1.5e-18 67.2 0.0 3.4e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 PXF46893.1 - 3.3e-06 27.2 0.0 0.0001 22.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AfaD PF05775.12 PXF46893.1 - 0.0065 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Enterobacteria AfaD invasin protein DEAD PF00270.29 PXF46893.1 - 0.0073 16.1 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PXF46893.1 - 0.022 15.1 0.1 0.062 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PXF46893.1 - 0.03 14.1 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF46893.1 - 0.052 13.3 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 PXF46893.1 - 0.098 11.4 0.1 7.8 5.1 0.0 2.5 3 0 0 3 3 3 0 SNF2 family N-terminal domain AAA_22 PF13401.6 PXF46893.1 - 0.11 12.7 0.2 10 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain UDPGP PF01704.18 PXF46894.1 - 9.6e-188 624.0 0.6 1.1e-187 623.7 0.6 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF1647 PF07801.11 PXF46894.1 - 0.11 12.3 0.3 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) PPR_2 PF13041.6 PXF46895.1 - 7.9e-55 182.9 2.7 1.7e-10 40.9 0.0 9.8 7 1 2 9 9 9 8 PPR repeat family PPR PF01535.20 PXF46895.1 - 4.3e-43 142.6 14.3 2.2e-05 24.4 0.1 12.5 13 0 0 13 13 13 10 PPR repeat PPR_1 PF12854.7 PXF46895.1 - 3.9e-32 109.6 8.1 8.3e-07 28.6 0.0 11.2 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 PXF46895.1 - 1e-31 108.8 0.0 8.9e-07 28.9 0.0 6.7 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF46895.1 - 2.6e-23 82.5 0.0 4.2e-11 42.6 0.0 4.9 2 2 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PXF46895.1 - 3.8e-05 24.1 0.1 2.6 8.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat T3SS_needle_E PF08988.10 PXF46895.1 - 0.041 14.0 0.9 0.18 12.0 0.3 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Radical_SAM PF04055.21 PXF46895.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily PAP_fibrillin PF04755.12 PXF46896.1 - 4.9e-18 65.8 0.0 1.9e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 PAP_fibrillin D123 PF07065.14 PXF46897.1 - 1.8e-53 181.7 0.9 2.1e-52 178.2 0.9 2.4 1 1 0 1 1 1 1 D123 OTCace PF00185.24 PXF46898.1 - 3e-47 160.6 0.0 4.5e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 PXF46898.1 - 9.2e-41 139.3 0.0 1.3e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain zf-C3HC4_3 PF13920.6 PXF46899.1 - 1.9e-09 37.2 13.4 1.9e-09 37.2 13.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 PXF46899.1 - 3.9e-08 33.5 0.5 0.00027 21.2 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46899.1 - 7.5e-06 25.7 1.0 6 7.2 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 PXF46899.1 - 9.7e-06 25.8 15.4 9.7e-06 25.8 15.4 2.8 3 0 0 3 3 2 1 Ring finger domain TPR_11 PF13414.6 PXF46899.1 - 1.8e-05 24.3 0.0 0.7 9.6 0.0 4.4 4 0 0 4 4 4 1 TPR repeat zf-C3HC4_2 PF13923.6 PXF46899.1 - 8.6e-05 22.3 15.6 8.6e-05 22.3 15.6 3.3 5 0 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF46899.1 - 0.0001 22.1 16.2 0.0001 22.1 16.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.6 PXF46899.1 - 0.00011 22.6 0.0 0.91 10.1 0.2 3.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46899.1 - 0.00079 20.0 3.6 14 6.8 0.0 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 PXF46899.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF46899.1 - 0.0098 15.8 13.3 0.0098 15.8 13.3 2.4 2 0 0 2 2 1 1 zinc-RING finger domain TPR_9 PF13371.6 PXF46899.1 - 0.011 15.8 1.6 0.19 11.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF46899.1 - 0.033 14.4 1.7 4.6 7.5 1.1 3.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF46899.1 - 0.087 12.9 0.4 1.3 9.2 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 PXF46899.1 - 0.14 12.2 16.2 0.067 13.2 10.8 3.2 3 1 0 3 3 3 0 RING-type zinc-finger TPR_16 PF13432.6 PXF46899.1 - 0.39 11.4 8.9 3 8.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF46899.1 - 0.48 10.3 4.8 4.1 7.4 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 PXF46899.1 - 1.5 9.1 16.6 5.2 7.3 16.6 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PXF46899.1 - 1.6 8.7 19.5 0.084 12.7 13.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 PXF46901.1 - 1.3e-05 25.8 2.7 0.031 15.1 0.5 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46901.1 - 0.067 13.5 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RNase_H PF00075.24 PXF46902.1 - 7.7e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 RNase H SR-25 PF10500.9 PXF46902.1 - 0.99 9.0 6.9 0.17 11.5 1.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ProRS-C_1 PF09180.11 PXF46904.1 - 1.7e-22 79.4 0.8 4.4e-22 78.1 0.8 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 PXF46904.1 - 1.2e-17 63.8 0.1 2.9e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PXF46904.1 - 5.2e-17 62.4 0.0 9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RNase_T PF00929.24 PXF46905.1 - 1.1e-11 45.5 0.0 2.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 PXF46905.1 - 0.049 13.3 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease APG6_N PF17675.1 PXF46905.1 - 0.46 11.0 10.0 0.19 12.3 6.9 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_S13 PF00416.22 PXF46906.1 - 7.2e-52 175.1 2.6 8.4e-52 174.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF585 PF04522.12 PXF46906.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF585) SepZ PF06066.11 PXF46910.1 - 1.4 9.2 10.9 0.37 11.0 0.7 2.6 3 0 0 3 3 3 0 SepZ Ac81 PF05820.11 PXF46910.1 - 1.7 8.2 9.3 2.8 7.5 5.1 2.2 2 0 0 2 2 2 0 Baculoviridae AC81 Sel1 PF08238.12 PXF46911.1 - 5.8e-58 192.0 23.9 6.5e-08 33.0 0.3 10.7 10 0 0 10 10 10 9 Sel1 repeat Pkinase PF00069.25 PXF46911.1 - 3.9e-16 59.2 0.0 2.1e-15 56.8 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46911.1 - 4.4e-15 55.7 0.0 9.3e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.6 PXF46911.1 - 3.1e-06 27.7 7.1 0.0061 17.2 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat MIT PF04212.18 PXF46911.1 - 0.0026 17.8 18.3 6.5 6.9 0.1 8.6 10 0 0 10 10 10 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PXF46911.1 - 0.0026 18.3 11.2 3.7 8.4 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46911.1 - 0.011 15.7 14.5 33 4.8 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat MitMem_reg PF13012.6 PXF46911.1 - 0.053 13.9 0.1 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TPR_19 PF14559.6 PXF46911.1 - 0.076 13.5 15.4 3.1 8.4 0.1 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46911.1 - 0.85 9.4 0.0 0.85 9.4 0.0 6.6 7 0 0 7 7 7 0 TPR repeat TPR_17 PF13431.6 PXF46911.1 - 4.8 7.8 6.2 1.1e+02 3.6 0.1 5.0 3 2 0 3 3 3 0 Tetratricopeptide repeat RIBIOP_C PF04950.12 PXF46912.1 - 1.3e-67 228.3 0.3 3.8e-67 226.8 0.0 1.9 2 1 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PXF46912.1 - 6.7e-23 80.6 0.5 3.2e-22 78.4 0.0 2.5 3 0 0 3 3 3 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 PXF46912.1 - 2.8e-07 30.3 0.0 7.1e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PXF46912.1 - 0.00011 22.7 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 PXF46912.1 - 0.00029 20.9 0.1 0.00072 19.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF46912.1 - 0.001 19.4 0.0 0.004 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 PXF46912.1 - 0.0032 17.5 0.2 0.015 15.4 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 PXF46912.1 - 0.02 15.5 0.9 0.18 12.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 PXF46912.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase AAA_33 PF13671.6 PXF46912.1 - 0.023 14.8 2.0 0.071 13.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 PXF46912.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PXF46912.1 - 0.03 14.2 0.1 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 PXF46912.1 - 0.037 14.5 1.6 0.07 13.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 PXF46912.1 - 0.066 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 PXF46912.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Oleosin PF01277.17 PXF46913.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Oleosin ETRAMP PF09716.10 PXF46913.1 - 0.021 14.8 1.2 0.03 14.4 1.2 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NBD94 PF16830.5 PXF46913.1 - 0.032 14.6 0.6 0.044 14.2 0.6 1.2 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Fzo_mitofusin PF04799.13 PXF46913.1 - 0.096 12.2 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 fzo-like conserved region TRAF6_Z2 PF18048.1 PXF46917.1 - 0.029 14.5 0.8 0.068 13.3 0.8 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Tmemb_9 PF05434.11 PXF46917.1 - 0.31 10.9 3.5 0.48 10.3 1.3 2.1 2 0 0 2 2 2 0 TMEM9 Adenine_glyco PF03352.13 PXF46918.1 - 3.1e-70 235.5 0.7 3.9e-70 235.2 0.7 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Kelch_6 PF13964.6 PXF46919.1 - 1.9e-21 75.5 9.4 0.00023 21.3 0.3 5.9 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PXF46919.1 - 4.9e-14 51.6 20.5 0.024 14.2 3.1 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PXF46919.1 - 1.7e-10 40.9 11.5 0.00013 22.2 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PXF46919.1 - 1.7e-08 34.3 11.8 0.081 12.9 0.7 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PXF46919.1 - 3.8e-07 30.0 11.8 0.26 11.3 2.0 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 PXF46919.1 - 0.1 12.6 13.0 3.2 7.9 0.5 5.8 6 1 0 6 6 6 0 Kelch motif Vps52 PF04129.12 PXF46920.1 - 1.1e-78 265.2 1.3 1.5e-78 264.8 1.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 PXF46920.1 - 1.2e-05 23.9 0.4 0.071 11.5 0.0 3.3 2 1 1 3 3 3 3 Exocyst complex component Sec3 Exo70 PF03081.15 PXF46920.1 - 0.073 12.1 4.7 1.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Exo70 exocyst complex subunit DUF3510 PF12022.8 PXF46920.1 - 0.24 11.8 1.1 1.7 9.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Mem_trans PF03547.18 PXF46922.1 - 1e-20 73.5 7.5 8.2e-12 44.2 2.9 2.1 1 1 0 2 2 2 2 Membrane transport protein DUF805 PF05656.14 PXF46922.1 - 2.2 8.7 6.6 0.66 10.4 0.6 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF805) DUF455 PF04305.14 PXF46923.1 - 2.5e-75 253.2 0.0 3e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Prefoldin_2 PF01920.20 PXF46924.1 - 2.3e-06 27.5 2.9 2.9e-06 27.2 2.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4618 PF15397.6 PXF46924.1 - 0.0013 18.3 0.7 0.0013 18.3 0.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) PEP-utilisers_N PF05524.13 PXF46924.1 - 0.02 15.0 1.8 0.48 10.6 0.1 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF489 PF04356.12 PXF46924.1 - 0.032 14.2 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Prefoldin PF02996.17 PXF46924.1 - 0.038 13.9 1.5 0.25 11.2 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit MitMem_reg PF13012.6 PXF46924.1 - 0.046 14.1 0.1 10 6.6 0.0 2.0 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function GAIN PF16489.5 PXF46924.1 - 0.077 12.4 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain Pet100 PF09803.9 PXF46924.1 - 0.099 13.2 0.2 0.6 10.7 0.0 2.0 2 0 0 2 2 2 0 Pet100 Plk4_PB2 PF18409.1 PXF46924.1 - 0.11 13.2 1.9 6.9 7.4 0.6 2.0 1 1 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF2968 PF11180.8 PXF46924.1 - 0.25 11.0 4.8 3.9 7.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIVA PF05103.13 PXF46924.1 - 0.51 10.4 4.9 0.83 9.7 1.4 2.0 2 0 0 2 2 2 0 DivIVA protein CLZ PF16526.5 PXF46924.1 - 1.3 9.5 7.5 0.88 10.0 2.7 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nsp1_C PF05064.13 PXF46924.1 - 1.4 8.7 6.5 2.4 8.0 1.5 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region SlyX PF04102.12 PXF46924.1 - 1.6 9.4 6.4 12 6.6 1.2 2.2 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 PXF46924.1 - 1.9 8.3 7.4 9 6.1 3.9 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 PXF46924.1 - 2.1 8.8 5.8 15 6.1 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1963 PF09234.10 PXF46925.1 - 1.1e-10 42.4 0.0 1.2e-09 39.0 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) UPF0167 PF03691.14 PXF46925.1 - 0.16 11.8 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DCP2 PF05026.13 PXF46926.1 - 1.9e-28 98.6 1.0 4.5e-28 97.4 1.0 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 PXF46926.1 - 3.8e-16 59.3 0.0 8.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4050 PF13259.6 PXF46926.1 - 0.094 13.0 8.6 0.17 12.2 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) MOZ_SAS PF01853.18 PXF46927.1 - 7.3e-83 276.6 0.2 9.8e-83 276.2 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 PXF46927.1 - 1.2e-19 69.9 0.3 2.4e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PXF46927.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF46927.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CSG2 PF16965.5 PXF46927.1 - 0.22 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator PurA PF04845.13 PXF46928.1 - 7.5e-08 32.0 0.0 9.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein PurA PF04845.13 PXF46929.1 - 2.3e-11 43.5 0.1 9.2e-11 41.5 0.1 1.8 1 1 0 1 1 1 1 PurA ssDNA and RNA-binding protein Utp12 PF04003.12 PXF46930.1 - 0.0019 18.5 3.0 0.12 12.7 0.7 3.6 3 1 0 3 3 3 1 Dip2/Utp12 Family Lactonase PF10282.9 PXF46931.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 PXF46932.1 - 1.8e-45 152.0 20.5 3e-10 40.5 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46932.1 - 6.5e-22 77.6 0.1 0.00036 20.8 0.0 6.9 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 PXF46932.1 - 2.8e-10 39.8 0.4 5.3e-10 38.9 0.4 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 PXF46932.1 - 3.5e-08 33.5 2.5 0.017 15.0 0.0 4.3 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PXF46932.1 - 0.00042 19.7 0.0 0.014 14.7 0.0 2.6 1 1 2 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 PXF46932.1 - 0.053 12.5 0.0 18 4.2 0.0 3.2 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF46932.1 - 0.89 8.1 5.1 1.4 7.4 0.1 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Hint PF01079.20 PXF46933.1 - 1.3e-27 96.7 0.0 2.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Hint module Intein_splicing PF14890.6 PXF46933.1 - 0.03 14.3 0.1 0.48 10.4 0.1 2.2 1 1 1 2 2 2 0 Intein splicing domain DUF5462 PF17547.2 PXF46933.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5462) VPS13_C PF16909.5 PXF46934.1 - 3.7e-30 105.0 3.7 3.7e-27 95.2 0.2 2.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PXF46934.1 - 1.2e-27 97.3 0.0 1.9e-24 86.8 0.0 3.1 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PXF46934.1 - 1.2e-25 89.9 0.0 5.5e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 PXF46934.1 - 2e-12 47.1 0.0 8.4e-12 45.0 0.0 2.1 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 UBA PF00627.31 PXF46934.1 - 7.5e-05 22.5 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ATG_C PF09333.11 PXF46934.1 - 0.00032 21.0 0.1 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 PXF46934.1 - 0.072 11.9 0.0 0.23 10.3 0.0 1.8 1 0 0 1 1 1 0 Golgi-body localisation protein domain Amidase PF01425.21 PXF46935.1 - 5.5e-81 272.8 0.1 8.7e-81 272.2 0.1 1.3 1 0 0 1 1 1 1 Amidase EFP_N PF08207.12 PXF46936.1 - 1.2e-27 95.7 0.3 2.5e-27 94.7 0.3 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 PXF46936.1 - 2.8e-25 87.8 0.8 5.5e-25 86.9 0.8 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 PXF46936.1 - 2.7e-16 59.3 3.1 1.2e-15 57.3 1.3 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Pkinase PF00069.25 PXF46937.1 - 4.8e-22 78.6 0.0 1.1e-20 74.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46937.1 - 4.1e-07 29.5 0.0 8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF46937.1 - 6.8e-06 26.2 1.0 1.2e-05 25.4 1.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF46937.1 - 0.00039 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF46937.1 - 0.00043 19.2 0.0 0.00076 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF46937.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 PXF46937.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SLX9 PF15341.6 PXF46938.1 - 1.3e-05 25.6 8.2 1.3e-05 25.6 8.2 2.7 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 WD40 PF00400.32 PXF46939.1 - 1.6e-11 44.6 0.4 0.09 13.7 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF46939.1 - 7.4e-10 39.0 0.1 1.1 9.6 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BORG_CEP PF14957.6 PXF46939.1 - 0.081 14.1 1.8 0.19 12.9 1.8 1.6 1 0 0 1 1 1 0 Cdc42 effector Putative_PNPOx PF01243.20 PXF46939.1 - 0.084 13.1 0.0 0.94 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase PD40 PF07676.12 PXF46939.1 - 0.16 11.9 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Symplekin_C PF12295.8 PXF46940.1 - 9.7e-39 133.4 0.5 3.4e-38 131.6 0.5 2.0 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 PXF46940.1 - 2.5e-08 33.8 0.0 5.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) FANCI_S2 PF14676.6 PXF46940.1 - 1.5 9.1 4.2 18 5.6 0.0 4.2 3 1 0 3 3 3 0 FANCI solenoid 2 HEAT PF02985.22 PXF46940.1 - 2.2 8.7 5.5 37 5.0 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Lzipper-MIP1 PF14389.6 PXF46940.1 - 9.8 6.6 8.3 3.6 7.9 0.2 3.9 5 0 0 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 SIL1 PF16782.5 PXF46941.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Arm PF00514.23 PXF46941.1 - 0.00075 19.5 0.4 2.7 8.1 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PXF46941.1 - 0.0047 17.3 4.2 0.16 12.4 1.2 2.8 2 0 0 2 2 2 1 HEAT repeats DBD_HTH PF18430.1 PXF46941.1 - 0.02 14.7 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain IFRD PF05004.13 PXF46941.1 - 0.038 13.1 0.4 0.091 11.9 0.1 1.8 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 PXF46941.1 - 0.15 12.6 8.2 2.2 8.9 1.4 3.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 PXF46941.1 - 0.64 10.4 4.4 16 6.1 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat OAD_gamma PF04277.13 PXF46941.1 - 6.2 7.5 5.6 1.5 9.5 0.5 2.5 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-ribbon_3 PF13248.6 PXF46942.1 - 0.0029 16.9 3.2 0.0063 15.9 3.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF2614 PF11023.8 PXF46942.1 - 0.0033 17.5 0.2 0.0045 17.1 0.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain C1_1 PF00130.22 PXF46942.1 - 0.021 14.7 0.3 0.03 14.2 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 PXF46942.1 - 0.028 14.4 0.2 0.048 13.7 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 PXF46942.1 - 0.03 14.3 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 PXF46942.1 - 0.032 14.2 0.9 0.058 13.3 0.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.12 PXF46942.1 - 0.053 13.1 1.6 0.053 13.1 1.6 2.0 1 1 1 2 2 2 0 Desulfoferrodoxin, N-terminal domain FYVE PF01363.21 PXF46942.1 - 0.054 13.6 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 FYVE zinc finger tRNA-synt_1g PF09334.11 PXF46942.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) Zn_Tnp_IS1595 PF12760.7 PXF46942.1 - 0.13 12.3 0.4 0.31 11.0 0.4 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HC5 PF06221.13 PXF46942.1 - 0.66 10.0 3.6 10 6.2 4.0 2.1 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.6 PXF46942.1 - 0.78 9.7 3.1 18 5.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF3797 PF12677.7 PXF46942.1 - 2.6 8.0 5.2 1.4 8.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Rpn3_C PF08375.11 PXF46943.1 - 2.6e-22 79.0 4.5 2.6e-22 79.0 4.5 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 PXF46943.1 - 2.3e-20 73.0 0.0 6.3e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 PXF46943.1 - 0.00027 21.0 0.5 0.00094 19.2 0.1 2.2 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PXF46943.1 - 0.0024 17.3 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 SAC3/GANP family Sel1 PF08238.12 PXF46943.1 - 0.15 12.8 0.3 7.2 7.4 0.2 2.7 2 0 0 2 2 2 0 Sel1 repeat DUF179 PF02622.15 PXF46944.1 - 8.7e-22 77.8 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Nucleotid_trans PF03407.16 PXF46945.1 - 1.4e-06 28.5 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase AAA PF00004.29 PXF46946.1 - 6.4e-34 117.2 0.0 1.4e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PXF46946.1 - 0.00023 20.9 0.0 0.00082 19.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 PXF46946.1 - 0.002 17.9 0.1 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 PXF46946.1 - 0.0041 17.3 0.0 0.015 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 PXF46946.1 - 0.01 15.8 0.1 0.24 11.3 0.1 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 PXF46946.1 - 0.012 15.9 0.5 1.2 9.4 0.2 3.2 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.14 PXF46946.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 PXF46946.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PXF46946.1 - 0.047 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF46946.1 - 0.048 13.7 0.0 0.28 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 PXF46946.1 - 0.087 12.8 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2059 PF09832.9 PXF46946.1 - 0.16 12.1 0.6 0.51 10.4 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) VWA PF00092.28 PXF46947.1 - 3.8e-13 50.0 0.0 4.8e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF46947.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Peripla_BP_4 PF13407.6 PXF46947.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain VWA_2 PF13519.6 PXF46947.1 - 0.052 14.2 0.0 0.081 13.6 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 PXF46947.1 - 0.22 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Snf7 PF03357.21 PXF46948.1 - 5.6e-33 114.0 14.7 7.3e-33 113.6 14.7 1.0 1 0 0 1 1 1 1 Snf7 DUF98 PF01947.16 PXF46948.1 - 0.07 13.1 1.2 0.095 12.7 1.2 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase DUF150 PF02576.17 PXF46948.1 - 0.11 12.9 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 RimP N-terminal domain ACR_tran PF00873.19 PXF46948.1 - 0.14 9.8 2.4 0.15 9.6 2.4 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family AAA_23 PF13476.6 PXF46948.1 - 0.17 12.4 3.7 0.21 12.1 3.7 1.1 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 PXF46948.1 - 0.73 10.1 3.3 0.54 10.6 1.6 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 PXF46948.1 - 1.4 9.4 5.0 50 4.4 0.0 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Tnp_P_element_C PF12596.8 PXF46948.1 - 8.7 7.0 10.1 14 6.3 6.8 2.6 2 1 1 3 3 3 0 87kDa Transposase TIG PF01833.24 PXF46949.1 - 1e-20 73.6 2.8 2.9e-09 36.9 0.1 2.6 2 0 0 2 2 2 2 IPT/TIG domain GSDH PF07995.11 PXF46949.1 - 4.1e-09 36.2 0.1 7.1e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase YqaJ PF09588.10 PXF46951.1 - 9.8e-05 22.5 0.0 0.0004 20.6 0.0 1.9 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain DUF3675 PF12428.8 PXF46953.1 - 0.27 11.8 0.1 0.4 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF1963 PF09234.10 PXF46955.1 - 3.3e-10 40.8 0.0 3.6e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) AAA PF00004.29 PXF46956.1 - 3.7e-47 160.1 0.0 1.7e-36 125.6 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF46956.1 - 2.7e-08 34.4 0.4 0.036 14.5 0.1 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 PXF46956.1 - 6.6e-08 32.9 0.1 0.17 12.2 0.1 4.8 3 2 1 4 4 4 2 AAA domain AAA_lid_3 PF17862.1 PXF46956.1 - 2e-07 30.7 0.1 9.6e-06 25.3 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 PXF46956.1 - 1.8e-06 27.8 0.3 0.00059 19.6 0.0 2.7 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain PEX-1N PF09262.11 PXF46956.1 - 3.9e-06 27.2 0.2 1.2e-05 25.7 0.0 1.9 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_18 PF13238.6 PXF46956.1 - 7.4e-06 26.5 0.2 0.21 12.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 PXF46956.1 - 5.4e-05 23.2 0.3 1.3 8.9 0.0 3.9 3 1 0 3 3 3 2 NACHT domain Mg_chelatase PF01078.21 PXF46956.1 - 5.7e-05 22.6 0.1 0.0038 16.6 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 PXF46956.1 - 0.00013 22.1 0.0 0.005 17.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PXF46956.1 - 0.00015 21.5 0.0 0.62 9.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 PXF46956.1 - 0.00043 20.5 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PXF46956.1 - 0.00048 20.1 0.0 0.056 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 PXF46956.1 - 0.00067 19.6 0.0 0.97 9.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PXF46956.1 - 0.00072 19.6 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PXF46956.1 - 0.0014 18.1 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 PXF46956.1 - 0.0018 18.8 0.0 2.7 8.5 0.0 2.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 PXF46956.1 - 0.0025 18.2 0.0 0.79 10.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 PXF46956.1 - 0.0048 16.8 0.0 4.1 7.3 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 PXF46956.1 - 0.01 16.1 0.6 0.45 10.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 PXF46956.1 - 0.015 14.6 0.0 0.32 10.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 PXF46956.1 - 0.022 15.1 1.0 4.2 7.7 0.1 2.9 3 1 0 3 3 2 0 AAA domain AFG1_ATPase PF03969.16 PXF46956.1 - 0.05 12.5 0.0 0.9 8.4 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 PXF46956.1 - 0.057 13.1 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 PXF46956.1 - 0.066 12.8 0.0 4.7 6.8 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 PXF46956.1 - 0.07 12.8 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 PXF46956.1 - 0.072 13.0 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 PXF46956.1 - 0.078 12.7 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 PXF46956.1 - 0.093 12.4 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PXF46956.1 - 0.11 12.0 0.3 1.5 8.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain ResIII PF04851.15 PXF46956.1 - 0.13 12.3 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 PXF46956.1 - 0.14 11.7 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 PXF46956.1 - 0.17 11.8 0.3 12 5.7 0.1 2.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 PXF46956.1 - 0.25 10.5 1.0 8.9 5.4 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain TPT PF03151.16 PXF46957.1 - 3.7e-15 56.0 14.8 4.6e-15 55.7 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF46957.1 - 4.1e-07 30.3 27.2 1.3e-05 25.4 5.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PXF46957.1 - 0.00013 21.3 16.2 0.0002 20.7 16.2 1.3 1 1 0 1 1 1 1 UAA transporter family Phage_Coat_Gp8 PF05371.12 PXF46957.1 - 0.62 9.9 0.1 0.62 9.9 0.1 2.7 4 0 0 4 4 4 0 Phage major coat protein, Gp8 CLP_protease PF00574.23 PXF46958.1 - 1.2e-82 276.2 0.9 1.4e-82 276.0 0.9 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 PXF46958.1 - 0.061 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase MgtE_N PF03448.17 PXF46958.1 - 0.095 13.3 1.4 2.8 8.6 0.2 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain TPR_1 PF00515.28 PXF46959.1 - 4.1e-44 146.7 7.7 2e-06 27.3 0.0 10.1 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 PXF46959.1 - 4.3e-41 135.7 13.5 0.0005 20.0 0.0 10.3 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 PXF46959.1 - 5.6e-30 101.0 12.2 0.048 13.9 0.0 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 PXF46959.1 - 3.6e-21 75.4 9.8 3.1e-06 27.6 0.5 6.1 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 PXF46959.1 - 1.4e-20 72.2 10.9 0.0044 17.7 0.5 8.6 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 PXF46959.1 - 7.6e-20 70.3 21.9 0.00045 19.8 0.0 9.2 5 3 5 10 10 10 5 TPR repeat TPR_12 PF13424.6 PXF46959.1 - 2.4e-19 69.4 26.9 2.9e-05 24.3 0.4 7.0 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 PXF46959.1 - 2.9e-18 64.8 12.9 0.1 13.0 0.0 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 PXF46959.1 - 1.1e-15 57.9 24.0 7.7e-05 23.3 0.6 7.6 5 2 2 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 PXF46959.1 - 1.9e-14 52.5 17.8 0.0014 18.5 0.1 9.9 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF46959.1 - 6.7e-12 45.2 8.5 4.8 8.0 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF46959.1 - 6.5e-11 42.2 11.7 0.0046 17.1 1.2 5.0 3 1 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF46959.1 - 2.2e-10 40.6 17.6 0.0012 19.1 0.7 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 PXF46959.1 - 1.3e-05 24.4 0.5 0.04 12.9 0.1 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 PXF46959.1 - 0.00011 22.0 8.1 1.6 8.7 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF46959.1 - 0.00043 19.6 15.1 0.56 9.4 0.7 4.1 1 1 1 3 3 3 3 Tetratricopeptide repeat DUF3151 PF11349.8 PXF46959.1 - 0.0011 19.0 0.9 0.0046 17.1 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3151) TPR_20 PF14561.6 PXF46959.1 - 0.0085 16.4 2.7 3.5 8.0 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 PXF46959.1 - 0.084 11.8 8.0 0.66 8.8 4.4 3.4 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 SNAP PF14938.6 PXF46959.1 - 0.11 11.9 14.0 0.065 12.6 3.6 3.1 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 PXF46959.1 - 0.12 11.7 11.6 0.12 11.8 7.1 2.8 1 1 0 2 2 2 0 MalT-like TPR region MIT PF04212.18 PXF46959.1 - 0.75 9.9 9.6 48 4.1 0.3 5.0 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 PXF46959.1 - 3.3 8.1 6.7 24 5.3 0.7 2.8 2 1 1 3 3 3 0 Bacterial transcriptional activator domain RcbX PF02341.15 PXF46960.1 - 4.5e-11 43.0 0.3 0.0026 18.0 0.1 3.4 3 1 0 3 3 3 3 RbcX protein Sod_Fe_C PF02777.18 PXF46961.1 - 2e-31 108.2 0.2 2.7e-31 107.8 0.2 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PXF46961.1 - 2.4e-09 37.5 0.0 6.1e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3972 PF13118.6 PXF46962.1 - 0.013 16.0 1.1 0.047 14.1 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) Sec2p PF06428.11 PXF46962.1 - 0.04 13.9 2.5 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Lebercilin PF15619.6 PXF46962.1 - 0.04 13.6 10.8 0.51 10.0 10.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 PXF46962.1 - 0.084 13.5 0.3 0.084 13.5 0.3 2.3 2 0 0 2 2 2 0 SlyX G_glu_transpept PF01019.21 PXF46962.1 - 0.096 11.4 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Cadherin_C_2 PF16492.5 PXF46962.1 - 0.22 12.3 0.9 0.47 11.2 0.9 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal UPF0242 PF06785.11 PXF46962.1 - 0.46 10.6 6.8 1.4 9.0 6.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3128 PF11326.8 PXF46962.1 - 0.72 10.3 3.8 46 4.5 3.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) YabA PF06156.13 PXF46962.1 - 2.4 8.8 6.4 2.5 8.8 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 PXF46964.1 - 0.00026 21.5 4.7 0.00032 21.2 4.7 1.2 1 0 0 1 1 1 1 Fez1 DUF3450 PF11932.8 PXF46964.1 - 0.0068 15.7 7.9 0.024 13.9 7.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) BRE1 PF08647.11 PXF46964.1 - 0.011 15.8 3.7 0.011 15.8 1.7 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.6 PXF46964.1 - 0.014 15.4 6.3 0.018 15.1 6.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SurA_N_2 PF13623.6 PXF46964.1 - 0.02 14.8 0.3 0.051 13.4 0.1 1.6 1 1 1 2 2 2 0 SurA N-terminal domain GAS PF13851.6 PXF46964.1 - 0.15 11.4 7.4 0.31 10.3 7.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 PXF46964.1 - 0.32 11.1 2.2 0.41 10.8 0.7 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4407 PF14362.6 PXF46964.1 - 0.45 9.8 4.7 0.57 9.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 PXF46964.1 - 0.61 10.3 9.2 0.28 11.4 5.1 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 PXF46964.1 - 2.4 8.5 7.5 1.3 9.5 2.5 2.6 1 1 0 2 2 2 0 Csm1 N-terminal domain Nup54 PF13874.6 PXF46964.1 - 3.2 7.9 10.2 5.3 7.1 10.2 1.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 ZapB PF06005.12 PXF46964.1 - 5.8 7.4 10.7 7.6 7.1 7.7 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Glyco_hydro_38N PF01074.22 PXF46965.1 - 3.3e-81 272.8 0.0 5.2e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PXF46965.1 - 2.8e-49 168.1 0.0 9.8e-49 166.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PXF46965.1 - 7.3e-23 80.5 0.1 1.6e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PXF46965.1 - 4.2e-11 42.8 0.0 9.2e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 PXF46965.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Pkinase PF00069.25 PXF46966.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46966.1 - 9e-38 130.0 0.0 3e-37 128.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF46966.1 - 1.6e-06 27.6 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF46966.1 - 6.9e-05 22.3 0.0 0.00041 19.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF46966.1 - 0.016 15.2 0.3 0.043 13.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF46966.1 - 0.03 13.3 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF46966.1 - 0.037 13.3 0.3 0.067 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF46966.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kelch_1 PF01344.25 PXF46966.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Kelch motif DUF16 PF01519.16 PXF46967.1 - 0.015 15.8 4.0 0.67 10.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMEM247 PF15444.6 PXF46967.1 - 0.039 14.0 1.2 0.043 13.9 0.8 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 DUF4080 PF13311.6 PXF46967.1 - 0.21 11.8 2.7 0.19 11.9 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4080) Prominin PF05478.11 PXF46967.1 - 0.27 9.1 3.0 0.33 8.9 3.0 1.1 1 0 0 1 1 1 0 Prominin RVT_2 PF07727.14 PXF46968.1 - 6.3e-10 39.1 0.0 8.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.19 PXF46969.1 - 5.5e-05 22.9 0.0 8.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 PXF46971.1 - 1.2e-69 234.6 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF46971.1 - 9e-38 130.0 0.0 3e-37 128.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF46971.1 - 1.6e-06 27.6 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF46971.1 - 6.9e-05 22.3 0.0 0.00041 19.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF46971.1 - 0.016 15.2 0.3 0.043 13.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF46971.1 - 0.03 13.3 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF46971.1 - 0.037 13.3 0.3 0.067 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF46971.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kelch_1 PF01344.25 PXF46971.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kri1_C PF12936.7 PXF46972.1 - 1.7e-27 95.4 1.3 1.7e-27 95.4 1.3 3.0 3 0 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 PXF46972.1 - 5.3e-17 62.3 8.5 5.3e-17 62.3 8.5 4.9 5 1 0 5 5 5 1 KRI1-like family Nop25 PF09805.9 PXF46972.1 - 0.0089 16.5 6.8 0.0089 16.5 6.8 4.3 4 1 0 4 4 4 2 Nucleolar protein 12 (25kDa) Hydrolase_4 PF12146.8 PXF46973.1 - 1.1e-36 126.3 0.0 7e-36 123.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF46973.1 - 2.8e-09 37.0 0.1 1.7e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF46973.1 - 2.1e-07 31.8 0.1 2.5e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 PXF46973.1 - 8.3e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 PXF46973.1 - 0.00036 20.1 0.0 0.0039 16.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PXF46973.1 - 0.0098 15.7 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.13 PXF46973.1 - 0.023 14.4 0.0 0.075 12.7 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DDE_1 PF03184.19 PXF46974.1 - 6.3e-11 42.2 0.1 8e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Defensin_5 PF18251.1 PXF46974.1 - 0.29 11.3 1.1 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Fungal defensin Copsin VEFS-Box PF09733.9 PXF46979.1 - 5.1e-19 68.4 2.2 5.4e-19 68.4 0.3 2.0 3 0 0 3 3 3 1 VEFS-Box of polycomb protein LSM PF01423.22 PXF46980.1 - 2.3e-17 62.4 0.2 2.9e-17 62.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF46980.1 - 0.012 15.7 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain KxDL PF10241.9 PXF46982.1 - 7.3e-09 35.8 0.6 7.3e-09 35.8 0.6 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein BRE1 PF08647.11 PXF46982.1 - 0.0015 18.6 1.1 0.0023 18.0 1.1 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 PXF46982.1 - 0.016 15.5 0.5 0.024 14.9 0.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.9 PXF46982.1 - 0.037 14.0 1.9 0.61 10.1 1.5 2.0 1 1 0 1 1 1 0 Tumour suppressor protein DUF2937 PF11157.8 PXF46982.1 - 0.46 10.2 8.4 0.068 12.9 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Sld7_C PF18596.1 PXF46983.1 - 0.0014 18.7 0.1 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 Sld7 C-terminal domain UCR_Fe-S_N PF10399.9 PXF46983.1 - 0.29 10.5 1.8 0.29 10.5 0.4 1.8 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_M18 PF02127.15 PXF46984.1 - 4.1e-150 500.4 0.0 5.3e-150 500.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 PXF46984.1 - 1.2e-05 24.5 0.0 0.00048 19.2 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase LRR_6 PF13516.6 PXF46985.1 - 9.7e-16 56.4 20.1 0.16 12.1 0.0 10.6 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 PXF46985.1 - 4.9e-15 55.4 14.1 0.024 15.1 0.0 7.2 4 2 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PXF46985.1 - 5e-07 29.4 14.2 0.0025 17.5 0.1 5.4 4 2 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 PXF46985.1 - 0.0013 19.0 20.4 14 6.7 0.4 9.0 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 PXF46985.1 - 0.058 12.9 1.7 1.5 8.3 0.1 3.1 1 1 3 4 4 4 0 Leucine-rich repeat MYT1 PF08474.11 PXF46985.1 - 0.27 11.1 1.4 0.7 9.8 0.8 1.9 2 0 0 2 2 2 0 Myelin transcription factor 1 EBA-175_VI PF11556.8 PXF46985.1 - 0.47 10.8 2.8 3.1 8.2 2.1 2.6 2 0 0 2 2 2 0 Erythrocyte binding antigen 175 RIC1 PF07064.13 PXF46986.1 - 6.4e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 RIC1 DNA_photolyase PF00875.18 PXF46987.1 - 1.2e-20 74.2 1.5 5e-20 72.2 1.5 1.8 1 1 0 1 1 1 1 DNA photolyase Not3 PF04065.15 PXF46988.1 - 1.2e-87 293.2 18.7 1.8e-87 292.6 18.7 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 PXF46988.1 - 1.3e-38 132.1 0.2 3.1e-38 130.8 0.2 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Spc7 PF08317.11 PXF46988.1 - 0.4 9.5 15.4 2 7.2 1.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 PXF46988.1 - 1.8 8.6 5.8 2.2 8.3 0.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 PXF46988.1 - 2 8.3 6.0 6 6.7 0.2 3.0 2 1 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 PXF46988.1 - 3.1 7.1 15.0 0.082 12.2 8.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 PXF46988.1 - 7.3 7.3 12.3 1.7 9.3 0.5 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DXP_synthase_N PF13292.6 PXF46994.1 - 1.4e-103 345.9 0.0 3.2e-103 344.7 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 PXF46994.1 - 5.7e-41 140.1 0.0 9.6e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PXF46994.1 - 6.7e-24 84.1 0.0 1.6e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 PXF46994.1 - 0.00014 21.0 0.1 0.25 10.3 0.0 3.1 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 PXF46994.1 - 0.0052 15.8 0.1 0.0081 15.1 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PCIF1_WW PF12237.8 PXF47002.1 - 2.9e-05 23.7 0.0 5.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain DUF410 PF04190.13 PXF47002.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) His_biosynth PF00977.21 PXF47003.1 - 3.3e-49 167.4 0.1 1.1e-48 165.8 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 PXF47003.1 - 3.2e-15 56.4 0.0 5.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 PXF47003.1 - 8.6e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 PXF47003.1 - 0.00013 21.8 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family NMO PF03060.15 PXF47003.1 - 0.011 15.1 0.3 0.031 13.7 0.1 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase TIM PF00121.18 PXF47004.1 - 6.1e-82 274.6 0.0 7.1e-82 274.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LSM PF01423.22 PXF47005.1 - 6.9e-23 80.1 0.0 8e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF47005.1 - 0.00014 21.9 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 PXF47005.1 - 0.064 13.4 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Transglut_C PF00927.22 PXF47006.1 - 0.11 12.6 0.4 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain A2M PF00207.22 PXF47006.1 - 0.15 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DDRGK PF09756.9 PXF47007.1 - 1.9e-44 151.5 28.8 2.5e-44 151.1 28.8 1.1 1 0 0 1 1 1 1 DDRGK domain Rrn6 PF10214.9 PXF47007.1 - 0.061 11.8 2.0 0.073 11.6 2.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 PXF47007.1 - 0.26 11.4 1.0 0.35 11.0 1.0 1.3 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 PXF47007.1 - 0.31 9.4 0.0 0.39 9.1 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 PXF47007.1 - 0.92 8.5 5.2 1.3 8.0 5.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 BUD22 PF09073.10 PXF47007.1 - 1.7 7.9 23.4 2.3 7.5 23.4 1.2 1 0 0 1 1 1 0 BUD22 FGF-BP1 PF06473.12 PXF47007.1 - 2.2 8.1 12.5 3.7 7.3 12.5 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PPL5 PF18168.1 PXF47007.1 - 2.8 7.1 7.2 4.1 6.6 7.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 CCDC71L PF15374.6 PXF47007.1 - 2.9 7.1 12.2 3.5 6.8 12.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L RR_TM4-6 PF06459.12 PXF47007.1 - 3.2 7.5 18.4 4.7 7.0 18.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PXF47007.1 - 9 4.9 16.0 1.2 7.8 11.7 1.6 2 0 0 2 2 2 0 Presenilin DUF913 PF06025.12 PXF47007.1 - 9.9 5.0 6.1 13 4.6 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DP PF08781.10 PXF47008.1 - 3.1e-10 40.1 0.0 6.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 PXF47008.1 - 4.6e-07 29.8 1.0 8.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DUF4303 PF14136.6 PXF47008.1 - 0.006 16.3 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4303) Cyt-b5 PF00173.28 PXF47009.1 - 2.3e-18 66.1 0.0 3e-17 62.5 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 PXF47009.1 - 2.9e-17 62.6 0.0 6.4e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 PXF47009.1 - 1.3e-09 38.0 0.0 2.5e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 PXF47009.1 - 8e-09 36.1 0.0 1.9e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DDE_Tnp_4 PF13359.6 PXF47011.1 - 3.5e-15 56.0 0.0 6.2e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PXF47011.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Plant_tran PF04827.14 PXF47012.1 - 5.7e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Plant transposon protein DUF3349 PF11829.8 PXF47012.1 - 0.12 13.1 0.0 0.26 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) Terpene_synth PF01397.21 PXF47012.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain rve PF00665.26 PXF47016.1 - 4.4e-09 36.6 0.0 5.7e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain SAPS PF04499.15 PXF47017.1 - 0.51 9.1 3.2 0.53 9.0 3.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RVT_2 PF07727.14 PXF47018.1 - 1.9e-32 112.8 0.0 2.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 PXF47020.1 - 4.5e-15 55.2 23.6 4.6e-05 23.6 5.4 3.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF47020.1 - 4.6e-15 55.3 18.4 1.7e-06 28.2 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF47020.1 - 1.4e-10 41.1 23.8 0.00091 19.9 1.7 3.5 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PXF47020.1 - 8.8e-05 22.2 22.0 0.0059 16.3 2.9 4.3 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 PXF47020.1 - 0.00013 22.7 7.6 0.84 10.3 0.2 3.0 1 1 2 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 PXF47020.1 - 0.0005 19.8 10.0 0.085 12.6 0.1 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 PXF47020.1 - 0.00058 20.1 1.3 0.014 15.7 0.6 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_7 PF15269.6 PXF47020.1 - 0.0054 16.8 3.4 0.0054 16.8 3.4 2.7 2 1 1 3 3 3 1 Zinc-finger zf-met PF12874.7 PXF47020.1 - 0.0068 16.8 15.1 0.051 14.0 0.3 3.7 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 PXF47020.1 - 0.013 15.8 6.0 0.02 15.2 5.9 1.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon BolA PF01722.18 PXF47020.1 - 0.013 15.7 6.1 0.11 12.8 0.8 2.1 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_2 PF12756.7 PXF47020.1 - 0.015 15.6 11.7 0.13 12.6 3.2 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 PXF47020.1 - 0.03 14.4 2.9 3.2 7.9 0.1 2.9 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Zf_RING PF16744.5 PXF47020.1 - 0.087 13.0 1.2 4.5 7.5 0.1 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger PyrI_C PF02748.15 PXF47020.1 - 0.1 12.5 4.1 1.8 8.6 2.2 2.4 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Actin_micro PF17003.5 PXF47020.1 - 0.12 11.5 8.2 1.2 8.3 1.7 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-BED PF02892.15 PXF47020.1 - 0.21 11.6 14.2 1.1 9.4 1.6 2.8 2 2 0 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 PXF47020.1 - 0.31 11.2 8.3 4 7.6 2.7 2.7 2 1 0 2 2 2 0 Zinc ribbon domain FOXP-CC PF16159.5 PXF47020.1 - 0.39 11.4 9.9 1 10.1 1.4 3.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-MYST PF17772.1 PXF47020.1 - 0.44 10.2 4.9 2.6 7.7 0.3 2.4 2 1 0 2 2 2 0 MYST family zinc finger domain IBR PF01485.21 PXF47020.1 - 0.64 10.3 8.0 0.34 11.2 1.7 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Elf1 PF05129.13 PXF47020.1 - 0.83 9.7 6.9 2.4 8.3 0.7 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 PXF47020.1 - 1.2 9.4 9.0 2.8 8.2 0.5 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain DUF629 PF04780.12 PXF47020.1 - 5.4 5.4 12.6 4.1 5.8 2.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Pkinase_Tyr PF07714.17 PXF47022.1 - 2.3e-49 168.0 0.0 3.6e-45 154.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PXF47022.1 - 8.4e-40 136.8 0.0 2.9e-36 125.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain EF-hand_7 PF13499.6 PXF47022.1 - 3.6e-16 59.4 2.8 1.5e-10 41.3 0.1 3.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PXF47022.1 - 2.6e-12 45.6 2.3 0.00017 21.3 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PXF47022.1 - 6.8e-10 37.8 4.7 0.0059 16.1 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 PXF47022.1 - 5.3e-07 29.4 0.3 0.084 12.7 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair Kdo PF06293.14 PXF47022.1 - 2.2e-06 27.2 0.2 5.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF47022.1 - 4.1e-05 23.6 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF47022.1 - 7e-05 21.8 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_5 PF13202.6 PXF47022.1 - 0.00071 19.0 0.0 1.2 8.8 0.0 3.3 2 0 0 2 2 2 2 EF hand DUF1679 PF07914.11 PXF47022.1 - 0.0071 15.3 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 PXF47022.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain URO-D PF01208.17 PXF47023.1 - 2.3e-91 306.5 0.0 2.6e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FGGY_N PF00370.21 PXF47024.1 - 3.2e-18 66.2 0.0 1.2e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PXF47024.1 - 1.3e-09 38.0 3.0 2.8e-09 37.0 2.1 2.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain NDUF_C2 PF06374.11 PXF47028.1 - 0.0013 18.8 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Pox_A_type_inc PF04508.12 PXF47030.1 - 1.8 8.6 5.0 18 5.4 0.8 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PMEI PF04043.15 PXF47030.1 - 4.8 7.5 9.5 0.37 11.1 3.1 2.4 2 2 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Fib_alpha PF08702.10 PXF47030.1 - 5.6 7.1 6.3 4.3 7.5 0.4 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 PXF47031.1 - 4e-76 255.9 0.0 5e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47031.1 - 2.3e-42 145.1 0.0 2.8e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF47031.1 - 1.9e-07 30.7 0.0 0.00032 20.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PXF47031.1 - 4e-06 25.9 0.0 7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF47031.1 - 0.0005 20.1 0.0 0.31 10.9 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 PXF47031.1 - 0.0085 15.7 0.1 0.035 13.7 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PH PF00169.29 PXF47031.1 - 0.013 16.0 0.9 0.052 14.1 0.9 2.0 1 1 0 1 1 1 0 PH domain RIO1 PF01163.22 PXF47031.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PXF47031.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIF3 PF05006.12 PXF47031.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 3 PUF PF00806.19 PXF47032.1 - 5e-07 29.1 0.0 2 8.3 0.0 6.3 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat Efg1 PF10153.9 PXF47033.1 - 2.1e-19 70.0 13.8 2.1e-19 70.0 13.8 1.7 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Exonuc_VII_L PF02601.15 PXF47033.1 - 0.58 9.7 5.6 0.7 9.4 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 PXF47033.1 - 4.5 5.1 6.0 5.1 4.9 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 PXF47035.1 - 0.16 12.1 21.3 0.11 12.6 17.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 PXF47035.1 - 1.7 8.8 19.8 6 7.1 19.8 1.9 1 1 0 1 1 1 0 bZIP transcription factor MGC-24 PF05283.11 PXF47036.1 - 0.078 13.4 1.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4355 PF14265.6 PXF47036.1 - 0.24 11.6 10.0 0.5 10.6 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SPESP1 PF15754.5 PXF47036.1 - 0.62 9.2 7.8 0.19 10.9 4.8 1.5 1 1 1 2 2 2 0 Sperm equatorial segment protein 1 bZIP_1 PF00170.21 PXF47036.1 - 3.3 7.9 23.0 11 6.2 22.8 1.9 1 1 0 1 1 1 0 bZIP transcription factor UL42 PF17638.2 PXF47037.1 - 0.0062 16.5 1.7 0.024 14.6 1.7 2.0 1 0 0 1 1 1 1 HCMV UL42 bZIP_2 PF07716.15 PXF47037.1 - 0.11 12.6 18.0 0.54 10.4 18.0 2.1 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 PXF47037.1 - 0.11 12.6 16.9 0.22 11.7 16.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 PXF47038.1 - 0.00015 21.7 10.7 0.00015 21.7 10.7 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF47038.1 - 0.00061 20.3 8.0 0.0014 19.1 8.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF1515 PF07439.11 PXF47038.1 - 0.024 14.7 1.2 0.58 10.2 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Neur_chan_memb PF02932.16 PXF47038.1 - 0.1 12.6 1.2 0.15 12.1 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EBP50_C PF09007.11 PXF47038.1 - 0.27 12.2 8.3 0.29 12.1 5.5 2.2 2 0 0 2 2 2 0 EBP50, C-terminal bZIP_1 PF00170.21 PXF47038.1 - 0.35 11.0 15.0 0.64 10.2 15.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor EF-hand_7 PF13499.6 PXF47040.1 - 5.5e-21 74.8 2.9 7.9e-20 71.1 0.7 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_13 PF17958.1 PXF47040.1 - 1.4e-16 60.0 0.1 2.1e-15 56.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PXF47040.1 - 0.0001 21.6 1.4 0.027 14.0 0.3 3.4 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 PXF47040.1 - 0.00025 20.4 0.4 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PXF47040.1 - 0.00061 19.5 2.0 0.079 12.9 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 PXF47040.1 - 0.0035 17.2 0.9 0.039 13.8 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair HAD_2 PF13419.6 PXF47041.1 - 0.0012 19.0 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF47041.1 - 0.016 15.2 0.2 0.034 14.2 0.1 1.6 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase PF00702.26 PXF47041.1 - 0.018 15.3 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF218 PF02698.17 PXF47041.1 - 0.06 13.4 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain Sel1 PF08238.12 PXF47042.1 - 1.7e-25 88.8 1.9 0.00014 22.4 0.0 7.6 8 0 0 8 8 8 5 Sel1 repeat TPR_6 PF13174.6 PXF47042.1 - 1.2e-09 38.2 1.2 0.078 13.7 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PXF47042.1 - 0.013 16.0 7.1 0.073 13.6 0.6 3.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF47042.1 - 0.034 14.8 12.8 1.7 9.3 0.1 5.7 5 1 2 7 7 7 0 Tetratricopeptide repeat Arg_decarb_HB PF17810.1 PXF47042.1 - 0.15 12.3 0.7 40 4.6 0.1 3.3 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain TPR_21 PF09976.9 PXF47042.1 - 0.45 10.2 5.4 1.3 8.7 2.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 PXF47042.1 - 0.83 10.0 2.6 2.3 8.6 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 PXF47043.1 - 5.7e-11 42.5 0.0 9.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 PXF47043.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) SPOC PF07744.13 PXF47044.1 - 8e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 SPOC domain F-box-like PF12937.7 PXF47044.1 - 7.3e-08 32.2 1.9 1.1e-07 31.6 0.1 2.2 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 PXF47044.1 - 1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain HGTP_anticodon2 PF12745.7 PXF47044.1 - 0.068 12.7 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs BTK PF00779.19 PXF47044.1 - 0.18 11.7 1.4 0.36 10.7 1.4 1.4 1 0 0 1 1 1 0 BTK motif Elongin_A PF06881.11 PXF47044.1 - 0.18 12.3 0.1 0.27 11.8 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BRK PF07533.16 PXF47045.1 - 1e-17 63.4 0.2 3.5e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 BRK domain Nop10p PF04135.12 PXF47045.1 - 0.03 14.3 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DUF4006 PF13179.6 PXF47046.1 - 5.5 7.0 6.5 1.6 8.7 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Band_7 PF01145.25 PXF47048.1 - 2.3e-20 73.3 0.1 2.9e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 PXF47048.1 - 0.00044 20.0 0.1 0.0068 16.1 0.0 2.2 1 1 0 2 2 2 1 SPFH domain-Band 7 family Band_7 PF01145.25 PXF47049.1 - 3.5e-20 72.8 0.1 4.9e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 PXF47049.1 - 0.00036 20.3 0.1 0.00099 18.9 0.1 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family Glyco_transf_34 PF05637.12 PXF47050.1 - 1.4e-14 54.4 3.0 1.3e-09 38.1 0.1 3.2 2 1 1 3 3 3 3 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 PXF47050.1 - 0.00019 21.1 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 PXF47050.1 - 0.018 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase ABG_transport PF03806.13 PXF47050.1 - 0.14 10.4 0.1 0.24 9.6 0.0 1.4 2 0 0 2 2 2 0 AbgT putative transporter family Hint PF01079.20 PXF47051.1 - 4.9e-24 85.0 0.4 3e-23 82.5 0.4 2.0 1 1 0 1 1 1 1 Hint module Hint_2 PF13403.6 PXF47051.1 - 0.001 19.4 0.0 0.018 15.3 0.0 2.4 1 1 0 1 1 1 1 Hint domain Vint PF14623.6 PXF47051.1 - 0.022 14.6 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Hint-domain gp37_C PF12604.8 PXF47051.1 - 0.13 12.0 0.1 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Tail fibre protein gp37 C terminal Hydrolase_4 PF12146.8 PXF47053.1 - 4e-19 68.8 0.1 2.9e-13 49.6 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF47053.1 - 2.7e-09 37.1 0.2 2.5e-08 33.9 0.1 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF47053.1 - 1.1e-08 36.0 0.4 2.2e-08 35.0 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.17 PXF47053.1 - 0.00017 21.5 0.4 7.2 7.0 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_S9 PF00326.21 PXF47053.1 - 0.0028 17.2 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 PXF47053.1 - 0.0056 15.4 0.0 0.074 11.7 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 PXF47053.1 - 0.0058 16.5 0.0 4 7.2 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PXF47053.1 - 0.011 15.6 0.2 0.024 14.5 0.2 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 PXF47053.1 - 0.03 13.4 0.0 0.067 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) FSH1 PF03959.13 PXF47053.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 PXF47053.1 - 0.13 10.8 0.0 0.27 9.7 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II AT_hook PF02178.19 PXF47053.1 - 0.22 11.5 2.3 0.74 9.9 2.3 2.0 1 0 0 1 1 1 0 AT hook motif DUF5549 PF17703.1 PXF47053.1 - 0.87 9.2 4.1 0.18 11.4 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5549) Yos1 PF08571.10 PXF47056.1 - 2.4e-21 75.8 3.5 2.8e-21 75.6 3.5 1.1 1 0 0 1 1 1 1 Yos1-like UPF0139 PF03669.13 PXF47057.1 - 8.6e-14 51.2 0.0 9.3e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF1230 PF06799.11 PXF47057.1 - 0.14 12.3 0.2 0.17 12.0 0.2 1.1 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 KASH PF10541.9 PXF47057.1 - 7.8 6.8 7.5 27 5.1 7.5 1.8 1 1 0 1 1 1 0 Nuclear envelope localisation domain zf-C3HC4_3 PF13920.6 PXF47058.1 - 1.7e-11 43.8 7.8 3.5e-11 42.8 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF47058.1 - 2.4e-06 27.3 10.8 5.7e-06 26.1 10.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PXF47058.1 - 8.8e-05 22.8 9.3 8.8e-05 22.8 9.3 1.8 2 0 0 2 2 2 1 Ring finger domain HATPase_c PF02518.26 PXF47058.1 - 0.012 16.2 0.1 0.058 13.9 0.1 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spt20 PF12090.8 PXF47058.1 - 0.26 10.8 11.4 0.41 10.2 11.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PXF47058.1 - 1.1 9.1 13.1 1.8 8.5 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PXF47058.1 - 4.7 5.8 6.9 5.9 5.5 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lipase_3 PF01764.25 PXF47059.1 - 5.1e-20 71.8 0.0 5.8e-19 68.4 0.0 2.6 2 1 0 2 2 2 1 Lipase (class 3) GDP_Man_Dehyd PF16363.5 PXF47059.1 - 0.22 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Abhydrolase_6 PF12697.7 PXF47059.1 - 0.72 10.4 0.0 0.72 10.4 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family HEAT_2 PF13646.6 PXF47060.1 - 0.0025 18.2 0.2 60 4.1 0.0 4.8 4 0 0 4 4 4 3 HEAT repeats FancD2 PF14631.6 PXF47061.1 - 8e-06 23.6 0.2 1.2e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease GPAT_N PF14829.6 PXF47061.1 - 0.085 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal DIMCO_N PF16844.5 PXF47061.1 - 0.22 11.9 0.6 12 6.3 0.0 3.4 4 0 0 4 4 4 0 Dinitrogenase iron-molybdenum cofactor, N-terminal GRASP55_65 PF04495.14 PXF47062.1 - 8.1e-48 162.2 0.0 4.5e-36 124.2 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 PXF47062.1 - 8.5e-10 38.8 0.0 5.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PXF47062.1 - 1.9e-07 30.8 0.1 0.025 14.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 PXF47062.1 - 0.052 13.9 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 PDZ domain PGK PF00162.19 PXF47066.1 - 1.1e-149 498.6 0.3 1.2e-149 498.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FAM25 PF15825.5 PXF47066.1 - 0.051 13.9 1.8 8 6.9 0.0 2.8 2 0 0 2 2 2 0 FAM25 family DUF563 PF04577.14 PXF47067.1 - 6.7e-26 91.7 0.0 1.2e-25 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PMSR PF01625.21 PXF47070.1 - 3.5e-66 222.1 4.1 4.2e-66 221.9 4.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LSM PF01423.22 PXF47071.1 - 6e-08 32.3 0.1 9.6e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain Nop16 PF09420.10 PXF47072.1 - 1.6e-21 77.3 8.8 7.2e-16 58.8 0.8 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 HTH_32 PF13565.6 PXF47072.1 - 0.063 13.9 3.8 0.09 13.4 0.0 2.6 1 1 2 3 3 3 0 Homeodomain-like domain ACCA PF03255.14 PXF47072.1 - 0.065 13.1 0.5 0.065 13.1 0.5 1.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HTH_8 PF02954.19 PXF47072.1 - 0.84 9.5 4.4 0.54 10.1 0.8 2.5 2 1 0 2 2 2 0 Bacterial regulatory protein, Fis family ARID PF01388.21 PXF47073.1 - 7.1e-08 33.0 0.0 1.4e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TFIIA PF03153.13 PXF47074.1 - 0.08 12.9 7.4 0.1 12.6 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4716 PF15837.5 PXF47076.1 - 0.75 9.9 5.0 2.3 8.4 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) BAG PF02179.16 PXF47077.1 - 5.9e-11 42.6 1.7 4.8e-10 39.7 1.8 2.1 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 PXF47077.1 - 0.0013 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 PXF47077.1 - 0.0027 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF1664 PF07889.12 PXF47077.1 - 0.098 12.7 0.6 4 7.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 PXF47077.1 - 0.1 12.9 0.0 11 6.3 0.0 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2313 PF10076.9 PXF47078.1 - 0.06 13.2 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) AAA_12 PF13087.6 PXF47079.1 - 3.8e-26 91.9 0.0 6.8e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNase_H_2 PF13482.6 PXF47079.1 - 3.5e-21 75.9 0.3 6.4e-21 75.0 0.3 1.5 1 0 0 1 1 1 1 RNase_H superfamily AAA_11 PF13086.6 PXF47079.1 - 1.1e-14 54.9 0.2 4e-06 26.8 0.1 3.3 3 0 0 3 3 3 3 AAA domain AAA_30 PF13604.6 PXF47079.1 - 2.8e-07 30.4 0.0 2.5e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PXF47079.1 - 1.1e-05 25.3 0.2 0.29 10.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 PXF47079.1 - 9.8e-05 22.3 0.2 0.0043 16.9 0.1 3.6 3 1 0 3 3 3 1 Helicase AAA_19 PF13245.6 PXF47079.1 - 0.00036 20.9 0.0 0.0015 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PXF47079.1 - 0.0023 17.2 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 PXF47079.1 - 0.003 17.3 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ATPase_2 PF01637.18 PXF47079.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 PXF47079.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 PXF47079.1 - 0.018 15.5 0.1 0.07 13.5 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 PXF47079.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 PXF47079.1 - 0.068 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 PXF47079.1 - 0.07 12.5 0.5 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 PXF47079.1 - 0.077 12.2 0.0 0.23 10.6 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 PXF47079.1 - 0.078 13.2 0.1 0.25 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PXF47079.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 PXF47079.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 PXF47079.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 PXF47079.1 - 0.18 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 PXF47079.1 - 0.21 10.5 0.1 0.44 9.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Na_H_Exchanger PF00999.21 PXF47080.1 - 2.3e-56 191.2 40.5 3.5e-56 190.7 40.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_associated PF12669.7 PXF47080.1 - 0.12 12.8 3.4 3.7 8.0 0.1 3.3 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Cmc1 PF08583.10 PXF47081.1 - 3.7e-16 58.9 3.7 4.5e-16 58.6 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 PXF47081.1 - 0.006 16.3 0.8 0.0092 15.7 0.8 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 PXF47081.1 - 0.41 11.1 4.4 0.31 11.5 1.5 1.8 1 1 1 2 2 2 0 GCK domain COX17 PF05051.13 PXF47081.1 - 0.6 10.5 4.9 9 6.7 0.5 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 PXF47082.1 - 6.4e-61 206.0 0.1 7.8e-61 205.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47082.1 - 4e-18 65.6 0.0 6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF47082.1 - 0.00016 21.7 0.0 0.00049 20.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF47082.1 - 0.042 13.2 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF47082.1 - 0.047 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aminotran_1_2 PF00155.21 PXF47083.1 - 8.2e-35 120.6 0.0 1.1e-34 120.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 PXF47083.1 - 3.3e-05 22.9 0.0 0.00019 20.4 0.0 1.9 2 0 0 2 2 2 1 Allinase MMR_HSR1_Xtn PF16897.5 PXF47084.1 - 3.9e-39 132.9 0.6 6.1e-39 132.3 0.6 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 PXF47084.1 - 3.4e-22 78.3 0.0 6.2e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 PXF47084.1 - 1e-19 70.7 0.0 2.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF47084.1 - 5e-10 39.1 0.1 1.4e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PXF47084.1 - 1.5e-05 25.2 0.4 0.12 12.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 PXF47084.1 - 0.065 12.6 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Tic110 PF16940.5 PXF47085.1 - 1.3e-41 142.8 27.5 7e-17 61.1 3.5 5.0 3 1 2 5 5 5 5 Chloroplast envelope transporter ENT PF03735.14 PXF47085.1 - 0.0012 18.8 5.5 5.4 7.2 0.3 5.3 5 0 0 5 5 5 2 ENT domain HLH PF00010.26 PXF47085.1 - 0.064 13.2 0.3 3.6 7.6 0.0 3.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain FA_FANCE PF11510.8 PXF47086.1 - 5.2e-07 29.3 0.2 7.4e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE HEAT PF02985.22 PXF47086.1 - 0.13 12.6 0.2 1.2 9.6 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat E3_UbLigase_EDD PF11547.8 PXF47086.1 - 0.15 11.8 0.0 24 4.7 0.0 2.5 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD Malectin PF11721.8 PXF47087.1 - 2.1e-38 132.0 0.0 8e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 Malectin domain TIG PF01833.24 PXF47087.1 - 1.4e-20 73.1 14.8 2.2e-12 46.8 1.0 4.0 3 0 0 3 3 3 2 IPT/TIG domain Malectin_like PF12819.7 PXF47087.1 - 3e-07 29.9 0.0 0.018 14.2 0.0 2.4 2 0 0 2 2 2 2 Malectin-like domain GSDH PF07995.11 PXF47087.1 - 8e-07 28.7 0.0 4.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PA14 PF07691.12 PXF47087.1 - 0.0019 18.0 0.0 0.0062 16.4 0.0 1.8 2 0 0 2 2 2 1 PA14 domain PQQ_3 PF13570.6 PXF47087.1 - 7 7.3 10.2 0.89 10.1 0.2 4.0 5 0 0 5 5 5 0 PQQ-like domain BORCS6 PF10157.9 PXF47088.1 - 0.0015 18.8 0.8 0.0026 18.0 0.8 1.5 1 1 0 1 1 1 1 BLOC-1-related complex sub-unit 6 UPF0242 PF06785.11 PXF47088.1 - 0.0034 17.5 3.2 0.0039 17.3 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 PXF47088.1 - 0.0044 17.3 2.6 0.24 11.7 0.2 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 PXF47088.1 - 0.0066 16.7 4.9 0.012 15.8 4.8 1.5 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding RFC1 PF08519.12 PXF47088.1 - 0.012 15.8 0.5 0.014 15.5 0.5 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Med9 PF07544.13 PXF47088.1 - 0.013 15.6 4.5 0.34 11.0 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BAR_3 PF16746.5 PXF47088.1 - 0.015 15.0 0.7 0.019 14.7 0.7 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Laminin_II PF06009.12 PXF47088.1 - 0.021 14.9 5.8 0.037 14.0 5.8 1.5 1 1 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 PXF47088.1 - 0.023 13.6 4.1 0.027 13.3 4.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Glutaredoxin2_C PF04399.13 PXF47088.1 - 0.036 13.9 1.0 0.069 13.0 0.9 1.5 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain GCN5L1 PF06320.13 PXF47088.1 - 0.037 14.2 0.9 1 9.5 0.1 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) RmuC PF02646.16 PXF47088.1 - 0.042 13.0 9.6 0.02 14.0 1.3 2.0 1 1 1 2 2 2 0 RmuC family DUF2203 PF09969.9 PXF47088.1 - 0.052 14.3 1.1 0.092 13.5 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2205 PF10224.9 PXF47088.1 - 0.062 13.3 8.1 0.45 10.5 0.9 2.8 2 1 0 2 2 2 0 Short coiled-coil protein FlxA PF14282.6 PXF47088.1 - 0.073 13.1 9.5 0.25 11.3 6.0 2.2 1 1 2 3 3 3 0 FlxA-like protein NPV_P10 PF05531.12 PXF47088.1 - 0.085 13.3 4.3 1.5 9.3 0.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MtrB PF05440.12 PXF47088.1 - 0.12 12.8 0.2 6.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Fib_alpha PF08702.10 PXF47088.1 - 0.13 12.5 1.9 0.24 11.6 1.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PI3K_P85_iSH2 PF16454.5 PXF47088.1 - 0.13 11.8 3.4 0.24 11.0 3.3 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YabA PF06156.13 PXF47088.1 - 0.16 12.6 3.1 0.52 11.0 2.5 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Prefoldin_2 PF01920.20 PXF47088.1 - 0.22 11.5 3.0 1.4 8.9 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 PXF47088.1 - 0.26 11.7 8.8 0.34 11.3 1.3 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vps5 PF09325.10 PXF47088.1 - 0.31 10.5 6.9 0.37 10.3 6.9 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Noelin-1 PF12308.8 PXF47088.1 - 0.33 11.0 4.3 0.63 10.1 1.1 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein FliD_N PF02465.18 PXF47088.1 - 0.33 11.7 6.6 5.3 7.8 5.6 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus CorA PF01544.18 PXF47088.1 - 0.5 9.6 5.2 0.59 9.4 5.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DHR10 PF18595.1 PXF47088.1 - 0.55 10.3 9.5 0.65 10.1 0.7 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 PXF47088.1 - 0.95 9.7 6.4 24 5.2 6.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Gon7 PF08738.10 PXF47088.1 - 1.2 9.2 7.4 2.3 8.4 1.3 2.1 1 1 1 2 2 2 0 Gon7 family SlyX PF04102.12 PXF47088.1 - 1.9 9.2 8.7 4.1 8.1 1.5 2.8 1 1 2 3 3 3 0 SlyX EccE PF11203.8 PXF47088.1 - 2.2 8.6 8.4 11 6.4 0.4 2.4 1 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE zf-RING_2 PF13639.6 PXF47089.1 - 4.9e-10 39.6 3.7 7.6e-10 39.0 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 PXF47089.1 - 2.4e-08 33.5 2.5 3.9e-08 32.8 2.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PXF47089.1 - 4.7e-08 33.2 2.3 8.5e-08 32.4 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF47089.1 - 1.2e-07 31.4 4.4 1.9e-07 30.8 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF47089.1 - 3.6e-07 29.9 1.8 5.9e-07 29.2 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF47089.1 - 1.4e-06 28.1 2.4 2.4e-06 27.4 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PXF47089.1 - 9.8e-06 25.5 0.8 1.6e-05 24.9 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PXF47089.1 - 1.1e-05 25.2 2.8 2e-05 24.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF47089.1 - 2.3e-05 24.3 1.2 3.2e-05 23.8 0.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF47089.1 - 0.00068 19.4 3.8 0.0012 18.6 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 PXF47089.1 - 0.00068 19.7 5.0 0.0016 18.5 5.1 1.6 1 1 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 PXF47089.1 - 0.0015 18.8 4.6 0.0025 18.1 4.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.6 PXF47089.1 - 0.02 14.7 1.8 0.036 13.9 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 PXF47089.1 - 0.021 14.7 3.3 0.032 14.1 3.3 1.3 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 PXF47089.1 - 0.086 12.7 0.6 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 PXF47089.1 - 0.19 11.5 0.4 0.19 11.5 0.4 2.6 3 1 0 3 3 3 0 RING-like zinc finger zf-C3H2C3 PF17122.5 PXF47089.1 - 0.19 11.8 5.9 0.56 10.3 5.9 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 PXF47089.1 - 1.8 8.8 5.9 11 6.2 5.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Methyltransf_21 PF05050.12 PXF47090.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_25 PF13649.6 PXF47090.1 - 0.18 12.5 0.0 0.33 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CDP-OH_P_transf PF01066.21 PXF47091.1 - 0.0034 18.1 0.5 0.0034 18.1 0.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short PF00106.25 PXF47092.1 - 8.7e-43 146.1 0.0 1.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF47092.1 - 5.4e-32 111.2 0.0 7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF47092.1 - 2.7e-14 53.5 0.1 4e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF47092.1 - 0.00043 20.2 0.0 0.00071 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 PXF47092.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PXF47092.1 - 0.018 14.5 0.1 0.091 12.2 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PXF47092.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 PXF47092.1 - 0.037 13.4 0.0 0.094 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UAA PF08449.11 PXF47093.1 - 3.4e-61 207.1 9.7 4.2e-61 206.8 9.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF47093.1 - 1e-10 41.9 16.1 8.9e-09 35.6 7.7 2.5 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 PXF47093.1 - 0.00034 19.9 4.9 0.021 14.0 0.8 2.3 1 1 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 PXF47093.1 - 0.0057 15.7 0.3 0.0057 15.7 0.3 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF3522 PF12036.8 PXF47093.1 - 0.018 15.4 1.0 0.018 15.4 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) Spo7 PF03907.13 PXF47093.1 - 0.072 12.6 0.4 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Spo7-like protein TMEM234 PF10639.9 PXF47093.1 - 0.26 11.3 7.1 1.8 8.7 2.6 2.7 2 1 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 PXF47093.1 - 3.1 7.1 14.9 0.61 9.4 2.9 2.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family NIF PF03031.18 PXF47094.1 - 1.7e-18 66.9 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-GRF PF06839.12 PXF47095.1 - 4.8e-30 103.4 18.8 1.8e-15 56.8 5.8 2.7 2 0 0 2 2 2 2 GRF zinc finger SNF2_N PF00176.23 PXF47095.1 - 6.9e-25 87.5 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF47095.1 - 1.9e-13 50.7 0.0 4.6e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PXF47095.1 - 0.016 14.5 0.0 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Prenylcys_lyase PF07156.14 PXF47096.1 - 1.9e-54 185.1 0.1 2.5e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 PXF47096.1 - 1.5e-11 44.3 0.0 2.5e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF47096.1 - 5.6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF47096.1 - 2.6e-07 30.5 0.0 2.1e-06 27.6 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF47096.1 - 0.0002 21.4 0.1 0.019 14.9 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 PXF47096.1 - 0.00096 18.5 0.0 0.0089 15.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PXF47096.1 - 0.0014 17.4 0.1 0.59 8.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 PXF47096.1 - 0.0047 16.2 0.1 0.0077 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PXF47096.1 - 0.047 12.9 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF47096.1 - 0.11 11.6 0.2 0.2 10.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 PXF47096.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GDA1_CD39 PF01150.17 PXF47097.1 - 1.4e-81 274.4 0.0 1.6e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Got1 PF04178.12 PXF47098.1 - 7.8e-29 100.4 12.9 1.2e-28 99.8 12.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4787 PF16029.5 PXF47099.1 - 8e-18 64.3 4.3 1.2e-17 63.7 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) DUF547 PF04784.14 PXF47099.1 - 0.026 14.6 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF547 DUF3541 PF12060.8 PXF47099.1 - 0.032 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Conotoxin PF02950.17 PXF47099.1 - 0.9 10.6 9.0 0.25 12.4 5.6 1.8 2 1 0 2 2 2 0 Conotoxin Pox_A_type_inc PF04508.12 PXF47100.1 - 0.00066 19.4 3.0 0.21 11.5 0.6 2.9 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Filament PF00038.21 PXF47100.1 - 0.1 12.2 5.2 0.15 11.6 5.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein SHE3 PF17078.5 PXF47100.1 - 0.1 12.3 1.4 0.16 11.7 1.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HAUS-augmin3 PF14932.6 PXF47100.1 - 0.17 11.5 1.6 0.24 10.9 1.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ribosomal_S7e PF01251.18 PXF47102.1 - 0.036 13.8 0.2 0.047 13.4 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e YokU PF14122.6 PXF47102.1 - 0.047 13.7 0.1 0.082 12.9 0.1 1.5 1 1 0 1 1 1 0 YokU-like protein, putative antitoxin DUF4969 PF16339.5 PXF47102.1 - 0.088 13.2 0.1 0.13 12.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4969) Miga PF10265.9 PXF47104.1 - 0.045 12.7 6.3 0.047 12.7 6.3 1.1 1 0 0 1 1 1 0 Mitoguardin G-patch PF01585.23 PXF47106.1 - 6.4e-16 58.0 2.5 1.6e-15 56.7 2.5 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 PXF47106.1 - 8.7e-06 25.6 0.1 0.00016 21.6 0.0 2.6 2 1 0 3 3 3 1 R3H domain G-patch_2 PF12656.7 PXF47106.1 - 1.6e-05 24.9 2.1 1.6e-05 24.9 2.1 1.9 2 0 0 2 2 2 1 G-patch domain TBCC PF07986.12 PXF47107.1 - 3.1e-21 75.3 0.3 6.3e-21 74.3 0.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 PXF47107.1 - 0.00032 21.1 0.1 0.0005 20.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Peptidase_M13_N PF05649.13 PXF47108.1 - 1.4e-80 271.9 0.1 2.1e-80 271.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PXF47108.1 - 3.8e-58 196.5 0.0 6.9e-58 195.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Sec20 PF03908.13 PXF47109.1 - 4.5e-09 36.1 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Sec20 zf-RING_2 PF13639.6 PXF47110.1 - 3.8e-11 43.1 12.0 3.8e-11 43.1 12.0 3.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 PXF47110.1 - 1.2e-08 34.5 5.0 3.8e-08 32.9 5.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF47110.1 - 3.7e-05 23.5 12.6 3.7e-05 23.5 12.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF47110.1 - 7.2e-05 23.0 12.0 0.00031 21.0 12.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PXF47110.1 - 0.00056 19.9 5.2 0.0012 18.8 5.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PXF47110.1 - 0.0013 18.6 11.5 0.0013 18.6 11.5 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF47110.1 - 0.0024 17.8 10.2 0.0024 17.8 10.2 2.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF47110.1 - 0.0087 16.1 9.4 0.0087 16.1 9.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 PXF47110.1 - 0.095 12.9 8.0 0.78 10.0 8.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Roughex PF06020.11 PXF47110.1 - 0.16 11.0 2.2 0.23 10.5 2.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Zn_ribbon_17 PF17120.5 PXF47110.1 - 1.4 8.6 14.0 0.083 12.5 8.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PXF47110.1 - 2.3 8.1 10.6 6.9 6.6 10.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NUDIX PF00293.28 PXF47111.1 - 2.1e-14 53.7 0.4 3.7e-14 52.9 0.4 1.4 1 0 0 1 1 1 1 NUDIX domain RGI1 PF10843.8 PXF47111.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Respiratory growth induced protein 1 CENP-Q PF13094.6 PXF47112.1 - 0.018 15.2 3.0 0.018 15.2 3.0 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 PXF47112.1 - 0.031 14.4 13.6 0.022 14.8 7.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 PXF47112.1 - 0.084 13.3 11.9 1.4 9.4 7.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 PXF47112.1 - 0.16 12.3 6.9 0.085 13.2 3.9 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 PXF47112.1 - 0.17 12.6 8.7 1.9 9.2 4.4 2.7 2 0 0 2 2 2 0 Initiation control protein YabA FUSC PF04632.12 PXF47112.1 - 2.2 6.7 3.6 3.5 6.0 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2968 PF11180.8 PXF47112.1 - 2.4 7.8 15.5 0.41 10.3 11.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 PXF47112.1 - 4.7 7.4 16.2 1.2 9.3 9.5 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 PXF47112.1 - 5.1 6.3 11.2 0.38 10.0 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PP2C PF00481.21 PXF47113.1 - 2.5e-45 155.1 0.0 4.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF47113.1 - 9.2e-06 25.4 0.3 2.1e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Thioredoxin PF00085.20 PXF47114.1 - 3.8e-21 75.0 0.0 8.2e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 PXF47114.1 - 9.9e-18 63.9 0.0 2.5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 PXF47114.1 - 4.9e-15 55.0 0.0 1.7e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 PXF47114.1 - 2.1e-05 24.3 8.4 0.0058 16.5 1.5 3.8 3 0 0 3 3 3 2 STI1 domain Rad60-SLD PF11976.8 PXF47114.1 - 5.3e-05 23.0 0.0 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Thioredoxin_2 PF13098.6 PXF47114.1 - 0.015 15.8 0.0 0.068 13.6 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PXF47114.1 - 0.047 13.4 0.0 0.047 13.4 0.0 3.3 2 1 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.21 PXF47114.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 PXF47114.1 - 0.11 12.7 1.8 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like DIRP PF06584.13 PXF47115.1 - 2.4e-10 40.5 0.0 4.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 DIRP Plasmid_RAQPRD PF09686.10 PXF47115.1 - 0.0043 17.2 0.0 0.019 15.2 0.0 2.2 1 0 0 1 1 1 1 Plasmid protein of unknown function (Plasmid_RAQPRD) Rit1_C PF17184.4 PXF47116.1 - 7.9e-69 232.1 0.0 1.2e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 PXF47116.1 - 2e-05 24.8 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain PsbP PF01789.16 PXF47117.1 - 6.1e-12 46.0 0.1 7.2e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 PsbP SOR_SNZ PF01680.17 PXF47118.1 - 1.3e-109 364.8 2.7 1.8e-109 364.3 2.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 PXF47118.1 - 3.1e-08 33.2 6.0 1.6e-06 27.6 0.1 3.0 2 1 2 4 4 4 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 PXF47118.1 - 0.00028 20.1 0.2 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 PXF47118.1 - 0.0037 16.5 1.0 0.23 10.6 0.0 2.9 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 PXF47118.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 PXF47118.1 - 0.0066 15.7 0.0 0.19 10.9 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 PXF47118.1 - 0.011 15.2 0.5 0.37 10.2 0.1 2.8 2 1 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 PXF47118.1 - 0.046 13.1 2.3 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Cyclin_N PF00134.23 PXF47119.1 - 7.3e-33 113.0 4.3 1.6e-32 111.9 4.3 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain GHL6 PF14871.6 PXF47120.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 PhdYeFM_antitox PF02604.19 PXF47120.1 - 0.081 12.7 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system PSII_Pbs31 PF18240.1 PXF47120.1 - 0.11 12.9 0.2 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Photosystem II Psb31 protein DUF3232 PF11554.8 PXF47120.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Isochorismatase PF00857.20 PXF47120.1 - 0.14 12.3 0.1 0.34 11.1 0.1 1.6 1 1 0 1 1 1 0 Isochorismatase family Neur_chan_memb PF02932.16 PXF47120.1 - 0.15 12.1 0.2 0.21 11.6 0.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SGL PF08450.12 PXF47122.1 - 0.00011 21.8 0.0 0.033 13.8 0.0 2.6 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 PXF47122.1 - 0.0024 17.8 4.0 0.15 12.1 0.0 3.9 5 0 0 5 5 5 2 NHL repeat Str_synth PF03088.16 PXF47122.1 - 0.15 12.2 0.1 2.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Strictosidine synthase BING4CT PF08149.11 PXF47123.1 - 1.5e-33 114.4 0.9 8.1e-32 108.9 0.0 3.2 3 1 1 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 PXF47123.1 - 2.1e-06 28.4 0.3 0.0033 18.2 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 PXF47123.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Remorin_C PF03763.13 PXF47123.1 - 4.5 7.2 15.6 0.43 10.5 11.2 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region EamA PF00892.20 PXF47124.1 - 1.3e-18 67.5 25.8 5.2e-15 55.8 9.7 3.0 2 1 0 2 2 2 2 EamA-like transporter family DUF4281 PF14108.6 PXF47125.1 - 0.1 12.9 1.8 0.26 11.7 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) TctB PF07331.11 PXF47125.1 - 1.7 8.9 7.5 19 5.5 7.5 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PSII_BNR PF14870.6 PXF47126.1 - 8.9e-120 399.5 0.7 1.1e-119 399.2 0.7 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 PXF47126.1 - 3.1e-10 38.5 7.7 0.03 14.3 0.5 5.2 4 0 0 4 4 4 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 PXF47126.1 - 4.5e-09 35.6 0.0 0.0064 15.3 0.0 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, DUF4185 PF13810.6 PXF47126.1 - 0.00024 20.4 1.8 6.7 5.9 0.0 3.5 2 1 2 4 4 4 4 Domain of unknown function (DUF4185) TFIID_30kDa PF03540.13 PXF47127.1 - 9.7e-21 73.5 0.0 1.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit SLX9 PF15341.6 PXF47127.1 - 0.0014 19.0 0.0 0.0036 17.7 0.0 1.7 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 DUF1826 PF08856.11 PXF47129.1 - 2.2e-16 60.4 0.1 8.3e-14 52.0 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1826) Hint PF01079.20 PXF47131.1 - 2.4e-16 59.9 0.0 5.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Hint module Hom_end_hint PF05203.16 PXF47131.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint SOG2 PF10428.9 PXF47131.1 - 1.2 8.2 15.2 1.8 7.7 15.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 PXF47131.1 - 2.9 6.3 7.0 3.9 5.9 7.0 1.1 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 PXF47131.1 - 4.1 6.6 13.8 6.2 6.1 13.8 1.1 1 0 0 1 1 1 0 BUD22 FAM220 PF15487.6 PXF47131.1 - 9.3 5.8 6.8 16 5.0 6.8 1.3 1 0 0 1 1 1 0 FAM220 family Proteasome PF00227.26 PXF47132.1 - 1.1e-35 122.8 0.1 1.4e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-RING_2 PF13639.6 PXF47133.1 - 3.6e-10 40.0 11.2 3.6e-10 40.0 11.2 2.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 PXF47133.1 - 7e-07 28.9 3.8 7e-07 28.9 3.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PXF47133.1 - 5.4e-06 26.2 6.4 5.4e-06 26.2 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF47133.1 - 6.8e-06 26.3 7.1 6.8e-06 26.3 7.1 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF47133.1 - 1.5e-05 24.8 10.2 1.5e-05 24.8 10.2 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF47133.1 - 5.3e-05 23.2 4.1 5.3e-05 23.2 4.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF47133.1 - 0.00052 19.9 10.5 0.0017 18.3 10.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF47133.1 - 0.017 15.0 8.1 0.055 13.3 8.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF47133.1 - 0.019 15.0 3.0 0.055 13.5 3.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PXF47133.1 - 0.095 12.3 8.4 0.28 10.8 8.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EGF_Tenascin PF18720.1 PXF47133.1 - 0.12 12.4 8.7 0.3 11.2 8.7 1.7 1 0 0 1 1 1 0 Tenascin EGF domain FANCL_C PF11793.8 PXF47133.1 - 1.4 9.1 8.6 5.2 7.3 8.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RFC1 PF08519.12 PXF47134.1 - 4.8e-38 130.8 0.0 1.7e-37 129.0 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 PXF47134.1 - 1.5e-12 48.1 0.0 3.8e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 PXF47134.1 - 4.3e-12 46.3 0.0 8.4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 PXF47134.1 - 9.9e-07 28.9 0.0 3.8e-06 27.0 0.0 2.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 PXF47134.1 - 0.00043 20.5 4.0 0.0028 17.8 0.1 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PXF47134.1 - 0.00047 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 PXF47134.1 - 0.00092 19.6 0.0 0.0033 17.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_assoc_2 PF16193.5 PXF47134.1 - 0.0074 16.6 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain NTPase_1 PF03266.15 PXF47134.1 - 0.052 13.5 0.1 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 NTPase AAA_16 PF13191.6 PXF47134.1 - 0.061 13.7 0.0 0.63 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PTCB-BRCT PF12738.7 PXF47134.1 - 0.075 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain AAA_22 PF13401.6 PXF47134.1 - 0.12 12.7 0.0 1.4 9.2 0.0 2.6 1 1 0 1 1 1 0 AAA domain Tetraspanin PF00335.20 PXF47135.1 - 1.5e-05 24.8 12.0 3e-05 23.8 12.0 1.6 1 1 0 1 1 1 1 Tetraspanin family Gaa1 PF04114.14 PXF47135.1 - 0.028 13.4 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component OST3_OST6 PF04756.13 PXF47135.1 - 0.38 10.1 3.4 1 8.6 3.4 1.7 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family EMP70 PF02990.16 PXF47135.1 - 1.3 7.6 4.7 2 7.0 4.7 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 Acyl_transf_3 PF01757.22 PXF47135.1 - 3.2 6.7 18.2 0.33 10.0 0.5 2.8 2 1 0 2 2 2 0 Acyltransferase family DUF2269 PF10027.9 PXF47135.1 - 9.1 6.3 12.3 0.58 10.2 2.1 2.7 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) tRNA-synt_His PF13393.6 PXF47136.1 - 7.7e-42 143.6 0.1 1.7e-41 142.5 0.0 1.6 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 PXF47136.1 - 8e-13 48.4 0.1 2.1e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 PXF47136.1 - 0.00013 21.2 0.1 0.025 13.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 PXF47136.1 - 0.00078 19.0 0.2 0.0025 17.3 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 PXF47136.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 PXF47136.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1819 PF08849.11 PXF47136.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) ABC_membrane PF00664.23 PXF47137.1 - 9.5e-33 114.0 12.4 1.2e-32 113.6 12.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PXF47137.1 - 2.1e-29 102.8 0.0 4.4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PXF47137.1 - 0.0049 16.3 0.2 0.04 13.4 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PXF47137.1 - 0.032 14.2 0.9 0.51 10.2 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase PalH PF08733.10 PXF47137.1 - 0.036 13.1 2.3 0.053 12.5 2.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 AAA_22 PF13401.6 PXF47137.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PXF47137.1 - 0.037 14.1 0.5 0.081 13.0 0.5 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 PXF47137.1 - 0.042 13.6 0.0 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 PXF47137.1 - 0.13 12.2 0.9 2.1 8.3 0.9 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Borrelia_P13 PF05628.12 PXF47137.1 - 0.14 12.1 0.7 6 6.8 0.0 2.3 2 0 0 2 2 2 0 Borrelia membrane protein P13 G-alpha PF00503.20 PXF47137.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Glyco_hydro_1 PF00232.18 PXF47138.1 - 3e-150 500.6 0.0 4.2e-150 500.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 RNase_H PF00075.24 PXF47138.1 - 9.6e-05 22.6 0.0 0.00032 20.9 0.0 1.9 1 0 0 1 1 1 1 RNase H WD40 PF00400.32 PXF47139.1 - 4.4e-07 30.5 8.3 0.0012 19.6 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47139.1 - 0.00012 22.3 0.0 0.007 16.6 0.0 3.1 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1995 PF09353.10 PXF47140.1 - 4.6e-28 98.6 0.0 5.5e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Ammonium_transp PF00909.21 PXF47141.1 - 1.8e-18 66.4 1.1 2.4e-18 66.0 1.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 PXF47142.1 - 3.3e-86 289.5 17.7 3.7e-86 289.3 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family VirB3 PF05101.13 PXF47142.1 - 2.2 8.6 6.2 2.5 8.4 0.2 2.9 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Ammonium_transp PF00909.21 PXF47143.1 - 5.6e-120 400.7 29.7 7.2e-120 400.3 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC1 PF03109.16 PXF47144.1 - 3.7e-22 78.7 0.0 6.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 PXF47144.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 PXF47144.1 - 0.038 13.4 0.0 5.2 6.3 0.0 2.6 2 1 0 2 2 2 0 Protein kinase domain MPC PF03650.13 PXF47145.1 - 6.7e-34 116.3 0.0 1.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Snf7 PF03357.21 PXF47146.1 - 2.9e-07 30.3 20.9 5.6e-07 29.3 20.9 1.6 1 1 0 1 1 1 1 Snf7 Glyco_hydro_106 PF17132.4 PXF47146.1 - 0.0041 15.5 2.3 0.0057 15.0 2.3 1.2 1 0 0 1 1 1 1 alpha-L-rhamnosidase NRDE-2 PF08424.10 PXF47146.1 - 0.2 10.7 8.3 0.27 10.3 8.3 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference CorA PF01544.18 PXF47146.1 - 0.33 10.2 10.9 0.54 9.5 10.0 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein YlbD_coat PF14071.6 PXF47146.1 - 1.2 9.4 13.3 0.071 13.4 5.1 2.4 1 1 1 2 2 2 0 Putative coat protein Bin3 PF06859.12 PXF47146.1 - 3.9 8.2 7.3 1.9 9.2 0.3 2.5 1 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) UbiA PF01040.18 PXF47147.1 - 6.8e-36 123.8 21.7 8.1e-36 123.6 21.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family CAF1 PF04857.20 PXF47148.1 - 2.1e-19 69.9 0.2 1.2e-09 37.8 0.0 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease MWFE PF15879.5 PXF47149.1 - 6.1e-15 55.1 0.0 7.3e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RBB1NT PF08169.11 PXF47149.1 - 0.066 13.4 0.0 0.066 13.4 0.0 1.1 1 0 0 1 1 1 0 RBB1NT (NUC162) domain RRM_1 PF00076.22 PXF47150.1 - 0.056 13.3 0.0 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.7 PXF47150.1 - 0.42 8.7 7.5 0.53 8.3 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CiPC PF15800.5 PXF47150.1 - 6.4 6.4 15.7 7 6.3 12.0 2.0 2 0 0 2 2 2 0 Clock interacting protein circadian RVT_2 PF07727.14 PXF47153.1 - 5.4e-09 36.1 0.0 6.4e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PXF47155.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 PXF47155.1 - 1.5 9.0 6.7 0.23 11.6 1.6 2.3 2 1 0 2 2 2 0 Integrase zinc binding domain Tfb4 PF03850.14 PXF47156.1 - 0.12 11.8 0.6 0.15 11.5 0.6 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 DEAD PF00270.29 PXF47158.1 - 3.9e-16 59.3 0.0 4.6e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DGOK PF05035.12 PXF47158.1 - 0.12 11.2 0.1 0.16 10.8 0.1 1.2 1 1 0 1 1 1 0 2-keto-3-deoxy-galactonokinase DUF2828 PF11443.8 PXF47159.1 - 3.6 5.6 9.8 5 5.1 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2058 PF09831.9 PXF47159.1 - 6.1 7.0 17.0 11 6.2 17.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RR_TM4-6 PF06459.12 PXF47159.1 - 7.4 6.3 10.7 13 5.5 10.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 PXF47159.1 - 9.1 5.0 14.4 12 4.6 14.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rhomboid PF01694.22 PXF47160.1 - 4.7e-16 59.1 8.0 7.6e-16 58.5 8.0 1.3 1 0 0 1 1 1 1 Rhomboid family DUF5506 PF17611.2 PXF47160.1 - 0.0029 17.5 0.5 0.0056 16.6 0.1 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5506) APH PF01636.23 PXF47161.1 - 0.00037 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF47161.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EMP70 PF02990.16 PXF47165.1 - 0.11 11.1 0.5 0.19 10.3 0.0 1.5 2 0 0 2 2 2 0 Endomembrane protein 70 MMS22L_N PF14910.6 PXF47166.1 - 0.028 12.9 0.1 0.041 12.3 0.1 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal WD40 PF00400.32 PXF47167.1 - 6.3e-06 26.8 4.6 0.062 14.2 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47167.1 - 0.0024 18.1 0.1 0.99 9.7 0.0 2.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.23 PXF47168.1 - 5.1e-34 118.1 0.0 9.3e-34 117.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PXF47168.1 - 2.4e-15 57.2 1.7 2.4e-15 57.2 1.7 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 PXF47168.1 - 3e-10 40.1 0.0 6.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 PXF47168.1 - 0.00047 20.8 0.0 0.49 11.1 0.0 2.9 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 PXF47168.1 - 0.0074 16.8 0.0 0.53 10.9 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease tRNA_synt_2f PF02092.17 PXF47169.1 - 3.1e-168 561.0 0.0 4e-168 560.7 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 PXF47169.1 - 1.1e-131 438.2 0.0 2.2e-131 437.2 0.0 1.5 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DALR_1 PF05746.15 PXF47169.1 - 5.9e-05 23.2 1.3 0.0022 18.2 0.4 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Atx10homo_assoc PF09759.9 PXF47170.1 - 5.9e-16 58.3 7.2 4.4e-05 23.4 0.1 5.5 3 1 3 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 PXF47170.1 - 5.1e-08 32.7 8.5 5 7.3 0.0 8.2 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 PXF47170.1 - 0.00059 19.4 1.3 0.047 13.1 0.0 3.1 3 0 0 3 3 3 1 Armadillo-like Mpv17_PMP22 PF04117.12 PXF47171.1 - 2.7e-14 53.1 1.7 4.5e-14 52.4 1.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BLM10_mid PF16507.5 PXF47172.1 - 3.4e-49 167.9 0.0 3.8e-38 131.4 0.0 2.2 1 1 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 PXF47172.1 - 6.2e-31 106.2 0.0 2.3e-30 104.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 PXF47172.1 - 0.001 18.7 0.6 0.29 10.7 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal RPT PF13446.6 PXF47172.1 - 0.0023 17.8 0.3 0.28 11.1 0.0 3.6 3 0 0 3 3 3 1 A repeated domain in UCH-protein HEAT PF02985.22 PXF47172.1 - 0.0028 17.8 0.1 1.6 9.2 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Drc1-Sld2 PF11719.8 PXF47172.1 - 0.098 12.2 0.4 0.32 10.5 0.7 1.6 2 0 0 2 2 2 0 DNA replication and checkpoint protein tRNA-synt_1b PF00579.25 PXF47173.1 - 9.6e-23 80.9 0.0 3.3e-22 79.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Lipocalin PF00061.23 PXF47173.1 - 0.084 13.1 0.2 0.67 10.2 0.0 2.5 2 1 1 3 3 3 0 Lipocalin / cytosolic fatty-acid binding protein family Chloroa_b-bind PF00504.21 PXF47174.1 - 2.7e-05 24.8 0.0 3.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 PXF47175.1 - 3.5e-05 24.4 0.1 4.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 PXF47177.1 - 0.00025 21.6 0.1 0.00029 21.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 PXF47178.1 - 3.5e-05 24.4 0.1 4.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HOOK PF05622.12 PXF47179.1 - 7.5e-06 24.4 25.3 7.5e-06 24.4 25.3 2.8 2 0 0 2 2 2 1 HOOK protein NAPRTase_C PF17956.1 PXF47179.1 - 0.83 10.1 6.5 0.14 12.6 0.7 2.8 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain Glyco_hydro_47 PF01532.20 PXF47180.1 - 4.8e-99 332.3 0.1 5.8e-99 332.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1993 PF09351.10 PXF47181.1 - 0.71 10.0 11.0 0.9 9.7 8.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) DUF1192 PF06698.11 PXF47181.1 - 1.5 8.9 8.5 0.35 11.0 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Spc7 PF08317.11 PXF47181.1 - 2.6 6.9 29.9 1.1 8.0 16.0 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 PXF47181.1 - 4.5 7.0 18.0 1.9 8.3 3.8 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MIEAP PF16026.5 PXF47181.1 - 6.1 7.0 11.2 17 5.5 8.1 2.4 2 1 0 2 2 2 0 Mitochondria-eating protein FUSC PF04632.12 PXF47181.1 - 6.3 5.2 21.7 8.2 4.8 20.8 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family Golgin_A5 PF09787.9 PXF47181.1 - 6.4 6.1 26.6 0.32 10.4 14.6 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 RGS_DHEX PF18148.1 PXF47181.1 - 6.7 6.9 10.4 7.2 6.8 1.4 2.9 2 1 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Rieske PF00355.26 PXF47182.1 - 8.2e-15 54.5 0.1 1.3e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 PXF47182.1 - 9.2e-13 48.0 0.2 2.5e-12 46.6 0.2 1.7 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit WHAMM-JMY_N PF15920.5 PXF47182.1 - 0.012 15.4 0.4 0.023 14.5 0.4 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated Ge1_WD40 PF16529.5 PXF47183.1 - 0.00077 18.5 0.0 0.0033 16.4 0.0 2.0 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ku_PK_bind PF08785.11 PXF47183.1 - 0.0046 17.1 1.0 0.012 15.8 0.1 2.2 2 0 0 2 2 2 1 Ku C terminal domain like CPL PF08144.11 PXF47184.1 - 7e-19 68.6 0.0 2.3e-15 57.2 0.0 4.1 3 2 1 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 PXF47184.1 - 0.0066 16.1 0.0 0.39 10.5 0.0 3.2 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat DUF3084 PF11283.8 PXF47184.1 - 0.24 11.4 1.7 29 4.7 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3084) COX16 PF14138.6 PXF47184.1 - 0.51 10.9 4.5 1.9 9.1 4.5 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Acetyltransf_1 PF00583.25 PXF47185.1 - 6.1e-13 49.0 0.0 7.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF47185.1 - 2e-10 40.9 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF47185.1 - 4.3e-10 39.6 0.0 6.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF47185.1 - 0.00054 19.9 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein NodA PF02474.15 PXF47185.1 - 0.00078 19.2 0.0 0.0021 17.8 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein A (NodA) Acetyltransf_9 PF13527.7 PXF47185.1 - 0.0032 17.5 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PXF47185.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ETF PF01012.21 PXF47188.1 - 3.9e-47 160.5 0.6 4.6e-47 160.2 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TonB_2 PF13103.6 PXF47188.1 - 0.11 12.7 0.1 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 TonB C terminal Pyr_redox_2 PF07992.14 PXF47190.1 - 7.3e-31 107.5 0.2 1.4e-30 106.6 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF47190.1 - 8e-12 45.5 0.4 4.8e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF47190.1 - 1.1e-10 41.7 1.9 0.00022 21.2 0.0 4.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 PXF47190.1 - 2.8e-05 23.4 3.0 0.048 12.7 0.2 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 PXF47190.1 - 7.1e-05 22.6 4.9 0.032 13.8 0.2 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF47190.1 - 0.00013 22.2 0.2 0.0023 18.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PXF47190.1 - 0.00033 20.0 7.0 0.21 10.8 0.1 4.0 2 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF47190.1 - 0.00061 19.0 8.0 0.23 10.5 0.2 3.4 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PXF47190.1 - 0.001 18.4 1.7 1.6 7.9 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.24 PXF47190.1 - 0.0015 17.7 0.1 0.0015 17.7 0.1 1.8 2 0 0 2 2 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 PXF47190.1 - 0.0098 15.2 2.1 0.46 9.7 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 PXF47190.1 - 0.021 15.1 0.4 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 PXF47190.1 - 0.037 13.7 0.3 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 PXF47190.1 - 0.12 12.6 0.2 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 PXF47190.1 - 0.13 11.1 0.1 0.13 11.1 0.1 2.7 3 1 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 PXF47190.1 - 0.17 11.2 1.2 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 ThiF family SNF2_N PF00176.23 PXF47191.1 - 6.6e-36 123.7 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF47191.1 - 5.4e-14 52.5 0.0 1.5e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF47191.1 - 3.7e-05 23.8 0.0 9.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PXF47191.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rotamase_3 PF13616.6 PXF47192.1 - 6.2e-20 71.9 0.0 1e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 PXF47192.1 - 1.6e-18 67.4 0.0 2.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.20 PXF47192.1 - 1.5e-10 41.5 0.0 2.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Rotamase_2 PF13145.6 PXF47192.1 - 1.8e-06 28.8 0.0 2.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain tRNA_synthFbeta PF17759.1 PXF47193.1 - 2.1e-47 161.3 0.0 3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 PXF47193.1 - 9.1e-33 112.3 0.2 5.1e-32 109.9 0.0 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 PXF47193.1 - 6.2e-27 94.4 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 PXF47193.1 - 2.5e-15 56.5 0.0 7.5e-13 48.6 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain Rotamase PF00639.21 PXF47194.1 - 1.1e-23 84.1 0.0 1.2e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PXF47194.1 - 2.7e-20 73.1 0.0 3e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PXF47194.1 - 0.00024 22.0 0.0 0.00027 21.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Elongin_A PF06881.11 PXF47195.1 - 1.1e-09 38.8 0.1 2e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_N_2 PF13409.6 PXF47196.1 - 2e-13 50.4 0.0 1.7e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF47196.1 - 1.9e-10 40.6 0.1 3.7e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PXF47196.1 - 0.00016 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF47196.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF244 PF03112.14 PXF47198.1 - 0.049 13.5 0.3 0.056 13.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Tmemb_161AB PF10268.9 PXF47199.1 - 2.1e-18 66.3 1.5 1.9e-16 59.8 0.0 2.4 1 1 0 2 2 2 2 Predicted transmembrane protein 161AB Colicin_V PF02674.16 PXF47199.1 - 1.3 9.0 12.8 0.024 14.6 4.0 2.6 3 0 0 3 3 3 0 Colicin V production protein MS_channel PF00924.18 PXF47200.1 - 2.7e-42 144.6 0.1 3.7e-42 144.2 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel RcsC PF09456.10 PXF47202.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) DUF1499 PF07386.11 PXF47203.1 - 3.3e-13 50.2 0.3 1e-12 48.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1499) RskA PF10099.9 PXF47203.1 - 0.059 13.7 6.4 0.083 13.2 6.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA C2 PF00168.30 PXF47204.1 - 8.2e-05 22.8 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.9 PXF47204.1 - 0.013 15.3 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3824 PF12868.7 PXF47204.1 - 0.036 14.7 0.4 0.051 14.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3824 PF12868.7 PXF47205.1 - 0.0021 18.8 4.3 0.0021 18.8 4.3 1.5 1 1 0 1 1 1 1 Domain of unknwon function (DUF3824) NT-C2 PF10358.9 PXF47205.1 - 0.0096 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 PXF47205.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 C2 domain DUF533 PF04391.12 PXF47205.1 - 0.3 10.7 5.0 0.43 10.1 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) Cwf_Cwc_15 PF04889.12 PXF47205.1 - 0.7 9.6 7.8 0.45 10.2 6.2 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lipase_3 PF01764.25 PXF47206.1 - 2.4e-19 69.6 0.0 5.3e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PXF47206.1 - 0.023 15.3 0.4 0.12 12.9 0.1 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PXF47206.1 - 0.055 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 PXF47206.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FBPase PF00316.20 PXF47207.1 - 1.5e-33 115.8 0.0 2.8e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain HTH_53 PF18606.1 PXF47207.1 - 0.16 11.6 0.0 27 4.5 0.0 2.5 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain DDHD PF02862.17 PXF47208.1 - 1.6e-25 90.6 0.0 2.7e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 DDHD domain PH PF00169.29 PXF47208.1 - 3.2e-09 37.2 0.0 5.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PXF47208.1 - 2.8e-05 24.3 0.3 4.7e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF676 PF05057.14 PXF47208.1 - 0.052 13.0 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 PXF47208.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PH_11 PF15413.6 PXF47208.1 - 0.26 11.7 0.7 1.1 9.7 0.7 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain GST_C PF00043.25 PXF47209.1 - 2.4e-06 27.7 0.0 3.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PXF47209.1 - 3.8e-05 23.6 0.4 0.00011 22.1 0.3 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF47209.1 - 4.4e-05 23.6 0.0 5.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Prominin PF05478.11 PXF47210.1 - 0.027 12.4 2.0 0.033 12.2 2.0 1.2 1 0 0 1 1 1 0 Prominin ETRAMP PF09716.10 PXF47210.1 - 0.16 12.0 6.9 5.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TRIC PF05197.13 PXF47211.1 - 2e-11 43.8 0.6 3.1e-11 43.2 0.6 1.2 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 PXF47211.1 - 0.0018 18.1 2.9 0.035 14.0 0.1 2.9 3 0 0 3 3 3 2 UPF0126 domain Metallophos PF00149.28 PXF47212.1 - 1.3e-16 61.7 0.8 2.2e-16 61.0 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 PXF47212.1 - 0.0011 18.1 0.1 0.43 9.6 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase DUF2934 PF11154.8 PXF47212.1 - 0.27 10.9 1.2 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) CBFD_NFYB_HMF PF00808.23 PXF47214.1 - 1.8e-15 56.9 0.2 3.1e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF47214.1 - 0.0018 18.7 0.1 0.0018 18.7 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 PXF47214.1 - 0.056 13.5 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-W PF15510.6 PXF47214.1 - 0.061 13.5 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 CENP-W protein HlyIII PF03006.20 PXF47215.1 - 1.9e-40 139.0 21.1 3.4e-40 138.1 21.1 1.4 1 1 0 1 1 1 1 Haemolysin-III related GFO_IDH_MocA PF01408.22 PXF47216.1 - 1.3e-13 51.8 0.0 3.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF47216.1 - 1.3e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NIP_1 PF08995.10 PXF47216.1 - 0.075 13.4 0.8 0.34 11.3 0.2 2.2 2 0 0 2 2 2 0 Necrosis inducing protein-1 Bromodomain PF00439.25 PXF47217.1 - 1.4e-10 41.1 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 PXF47219.1 - 1.4e-09 38.4 3.3 0.0018 19.0 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box PF00646.33 PXF47219.1 - 0.0032 17.3 0.2 0.0078 16.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 PXF47219.1 - 0.0091 16.3 0.4 2.7 8.4 0.1 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PXF47219.1 - 0.024 14.6 0.4 6.2 6.9 0.0 3.8 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 PXF47219.1 - 0.045 12.4 0.6 0.073 11.7 0.6 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4350 PF14258.6 PXF47219.1 - 0.11 13.0 0.5 4.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) PQQ_3 PF13570.6 PXF47219.1 - 1.8 9.2 11.8 12 6.5 2.1 4.9 6 0 0 6 6 6 0 PQQ-like domain Chloroa_b-bind PF00504.21 PXF47220.1 - 1.8e-33 116.3 0.0 2.3e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SNF2_N PF00176.23 PXF47221.1 - 2.5e-57 194.2 0.3 5.1e-57 193.2 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF47221.1 - 5.3e-10 39.6 0.0 1.1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 PXF47221.1 - 1.2e-06 28.7 9.8 1.2e-06 28.7 9.8 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PXF47221.1 - 0.00035 20.5 6.9 0.00035 20.5 6.9 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF47221.1 - 0.00058 19.7 9.3 0.00058 19.7 9.3 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF47221.1 - 0.0022 17.8 10.4 0.0022 17.8 10.4 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF47221.1 - 0.0029 17.5 7.8 0.0029 17.5 7.8 3.7 3 1 1 4 4 4 1 zinc-RING finger domain REV1_C PF16727.5 PXF47221.1 - 0.24 11.8 2.2 16 6.0 0.2 3.3 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain MFS_1 PF07690.16 PXF47222.1 - 2.9e-54 184.4 52.6 5e-54 183.6 42.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PXF47222.1 - 0.44 8.8 23.0 0.057 11.7 1.5 3.4 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PfkB PF00294.24 PXF47223.1 - 5.3e-24 85.0 0.0 8.4e-24 84.4 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF531 PF04407.12 PXF47223.1 - 0.027 14.6 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) eIF2_C PF09173.11 PXF47224.1 - 2e-35 120.9 0.1 4.5e-35 119.8 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 PXF47224.1 - 3e-24 85.6 0.5 2.4e-23 82.7 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PXF47224.1 - 2.3e-11 43.9 0.5 6e-11 42.6 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 PXF47224.1 - 0.00057 19.8 0.4 0.0093 15.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PXF47224.1 - 0.00059 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 PXF47224.1 - 0.019 15.0 0.1 0.057 13.4 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Tax PF02959.16 PXF47224.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax EBP50_C PF09007.11 PXF47225.1 - 0.97 10.4 24.9 37 5.3 24.9 2.2 1 1 0 1 1 1 0 EBP50, C-terminal PPP4R2 PF09184.11 PXF47225.1 - 1.6 8.2 13.9 1.7 8.1 13.9 1.0 1 0 0 1 1 1 0 PPP4R2 ASD2 PF08687.11 PXF47225.1 - 3.5 7.1 10.0 4.3 6.8 10.0 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Macoilin PF09726.9 PXF47225.1 - 6.1 5.3 20.5 6.9 5.1 20.5 1.2 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 PXF47225.1 - 9.1 6.3 8.3 10 6.1 8.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Myb_DNA-binding PF00249.31 PXF47227.1 - 0.00036 20.7 0.0 0.0009 19.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain COQ9 PF08511.11 PXF47228.1 - 7.1e-25 86.6 0.7 1.2e-24 85.9 0.4 1.5 1 1 0 1 1 1 1 COQ9 TetR_C_23 PF17931.1 PXF47228.1 - 0.019 15.1 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Myb_DNA-binding PF00249.31 PXF47230.1 - 6.5e-43 144.7 6.3 9e-15 54.6 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF47230.1 - 8.1e-31 106.1 2.9 2.5e-14 53.3 0.6 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF47230.1 - 2.9e-06 27.1 0.2 6.1e-05 22.8 0.1 2.5 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 PXF47230.1 - 0.0074 16.3 0.0 8.1 6.5 0.0 3.2 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 PXF47230.1 - 0.0096 16.3 4.9 0.03 14.7 0.2 3.1 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain DMAP_binding PF06464.11 PXF47230.1 - 0.015 16.1 2.1 0.015 16.1 2.1 2.8 3 0 0 3 3 3 0 DMAP1-binding Domain Romo1 PF10247.9 PXF47231.1 - 0.038 14.4 0.2 0.084 13.3 0.2 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 PAP2_3 PF14378.6 PXF47232.1 - 1.9e-17 63.6 15.4 3e-17 62.9 15.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 PXF47232.1 - 1.2e-05 25.1 8.3 1.2e-05 25.1 8.3 2.3 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 PXF47232.1 - 0.18 12.4 5.5 0.29 11.7 1.3 2.7 2 1 1 3 3 3 0 PAP2 superfamily C-terminal UCR_UQCRX_QCR9 PF05365.12 PXF47233.1 - 2.3e-17 62.7 0.1 2.7e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TolB_N PF04052.13 PXF47234.1 - 0.023 14.9 0.1 0.15 12.3 0.0 2.0 1 1 1 2 2 2 0 TolB amino-terminal domain Auto_anti-p27 PF06677.12 PXF47235.1 - 3.9e-27 94.1 13.8 5.1e-14 52.1 2.6 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 PXF47235.1 - 1.6 8.8 9.0 0.31 11.1 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 PXF47236.1 - 9.9e-65 218.5 0.0 1.4e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47236.1 - 1.5e-29 103.1 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF47236.1 - 2.8e-07 29.8 0.0 4.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PXF47236.1 - 8.6e-05 22.0 0.0 0.00031 20.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF47236.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF47236.1 - 0.0029 17.6 1.0 0.022 14.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family NUDIX_4 PF14815.6 PXF47242.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 NUDIX domain UQ_con PF00179.26 PXF47245.1 - 4.4e-17 62.1 0.0 4.8e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PXF47245.1 - 0.0067 16.3 0.0 0.0088 15.9 0.0 1.1 1 0 0 1 1 1 1 UEV domain Ribosomal_L1 PF00687.21 PXF47246.1 - 1.8e-41 142.2 4.6 2.2e-41 141.9 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family GTP_EFTU PF00009.27 PXF47247.1 - 6e-50 169.5 0.0 8.2e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 PXF47247.1 - 2.3e-44 150.4 0.0 3.8e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 PXF47247.1 - 1.1e-06 28.9 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF47247.1 - 2.6e-06 27.5 0.0 5.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 PXF47247.1 - 1.4e-05 25.0 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II TPR_19 PF14559.6 PXF47248.1 - 9.5e-11 42.1 14.8 0.00051 20.5 0.0 8.0 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF47248.1 - 2.4e-10 40.4 32.6 0.072 13.9 0.0 12.2 11 1 2 13 13 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF47248.1 - 3.9e-10 39.1 29.9 0.085 13.0 0.0 13.1 16 0 0 16 16 13 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF47248.1 - 1e-09 37.8 8.8 0.23 11.8 0.0 10.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF47248.1 - 2.6e-07 31.2 29.6 0.015 16.0 0.0 8.9 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF47248.1 - 1.5e-06 28.2 6.7 0.18 12.3 0.1 6.8 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF47248.1 - 1.4e-05 25.3 30.4 0.062 13.6 0.1 10.1 10 2 1 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF47248.1 - 5.6e-05 22.7 2.9 3 7.6 0.1 7.0 7 1 1 8 8 8 2 TPR repeat TPR_7 PF13176.6 PXF47248.1 - 0.00035 20.4 12.9 4.3 7.6 0.0 8.2 10 0 0 10 10 10 2 Tetratricopeptide repeat DUF4810 PF16068.5 PXF47248.1 - 0.0013 19.3 5.1 1.8 9.1 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4810) TPR_1 PF00515.28 PXF47248.1 - 0.0014 18.4 16.3 2.6 8.0 0.0 8.2 10 0 0 10 10 10 2 Tetratricopeptide repeat PPR PF01535.20 PXF47248.1 - 0.0027 17.9 0.0 0.54 10.6 0.0 4.0 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.6 PXF47248.1 - 0.0078 16.8 20.5 1.2 9.9 0.0 9.1 11 1 0 11 11 8 1 Tetratricopeptide repeat TPR_5 PF12688.7 PXF47248.1 - 0.086 13.1 2.0 5.3 7.3 0.0 4.0 3 1 1 4 4 3 0 Tetratrico peptide repeat TPR_4 PF07721.14 PXF47248.1 - 0.1 13.3 8.3 6.5 7.7 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 PXF47249.1 - 1.7e-06 27.4 0.0 2.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PXF47249.1 - 0.0014 17.7 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MCM PF00493.23 PXF47252.1 - 3e-95 317.6 0.0 6.4e-95 316.5 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PXF47252.1 - 6.5e-40 135.9 0.2 1.1e-39 135.1 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF47252.1 - 6.2e-29 100.3 0.1 1.6e-28 99.0 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PXF47252.1 - 1.2e-11 45.1 0.1 4.1e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 PXF47252.1 - 3.7e-08 33.5 0.1 2.7e-06 27.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PXF47252.1 - 8.5e-08 31.8 0.0 1.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PXF47252.1 - 0.0013 18.6 0.0 0.0048 16.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 PXF47252.1 - 0.0034 17.2 0.1 0.013 15.4 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 PXF47252.1 - 0.018 15.4 1.1 0.26 11.7 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 PXF47252.1 - 0.026 14.2 0.0 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 PXF47252.1 - 0.047 14.1 0.2 1.7 9.1 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RTP1_C1 PF10363.9 PXF47252.1 - 0.098 12.8 0.3 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 NTPase_1 PF03266.15 PXF47252.1 - 0.14 12.1 0.0 7.5 6.4 0.0 2.5 1 1 1 2 2 2 0 NTPase Cytochrome_C7 PF14522.6 PXF47252.1 - 0.93 9.5 4.1 0.84 9.7 1.7 2.2 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 PXF47252.1 - 1.7 9.2 4.5 0.47 11.0 0.8 1.9 3 0 0 3 3 1 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 PXF47252.1 - 3.6 8.1 5.4 2.1 8.9 1.2 2.6 3 0 0 3 3 3 0 Cytochrome c3 Pkinase PF00069.25 PXF47253.1 - 1.9e-67 227.4 0.0 2.6e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47253.1 - 2.3e-36 125.4 0.1 3.3e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF47253.1 - 5.6e-05 22.1 0.0 0.0001 21.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF47253.1 - 0.002 17.5 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF47253.1 - 0.04 13.2 0.0 0.16 11.2 0.0 2.0 1 1 0 2 2 2 0 Kinase-like DotA PF11388.8 PXF47253.1 - 0.19 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Abhydrolase_1 PF00561.20 PXF47254.1 - 3e-15 56.6 0.7 2.7e-12 46.9 0.3 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF47254.1 - 2.2e-12 46.8 1.5 2.9e-10 39.8 0.9 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF47254.1 - 1.6e-06 28.9 19.3 1.6e-05 25.6 19.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 PXF47254.1 - 4.2e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 PXF47254.1 - 0.00071 19.3 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 PXF47254.1 - 0.0044 16.7 0.1 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 PXF47254.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase SPX PF03105.19 PXF47254.1 - 1.6 8.6 6.9 2.1 8.2 6.9 1.2 1 0 0 1 1 1 0 SPX domain AF-4 PF05110.13 PXF47254.1 - 8.5 4.3 16.8 12 3.8 16.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA PF00004.29 PXF47255.1 - 2.7e-22 79.6 0.0 5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF47255.1 - 7.4e-06 26.3 0.1 0.00021 21.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PXF47255.1 - 2.1e-05 24.7 0.4 0.00014 22.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PXF47255.1 - 3.6e-05 24.3 0.1 0.0017 18.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PXF47255.1 - 4.5e-05 23.9 4.3 0.00018 22.0 0.3 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 PXF47255.1 - 0.0012 18.6 0.2 0.0034 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 PXF47255.1 - 0.0023 18.2 0.0 0.0071 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PXF47255.1 - 0.0025 17.8 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 PXF47255.1 - 0.0034 17.1 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PXF47255.1 - 0.0037 16.7 0.1 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 PXF47255.1 - 0.0049 16.2 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 KaiC KTI12 PF08433.10 PXF47255.1 - 0.0089 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_11 PF13086.6 PXF47255.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PXF47255.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 PXF47255.1 - 0.024 14.6 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 PXF47255.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 PXF47255.1 - 0.038 14.5 0.1 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PXF47255.1 - 0.04 13.5 0.2 0.13 11.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PXF47255.1 - 0.047 13.7 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PXF47255.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 PXF47255.1 - 0.059 13.1 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 PXF47255.1 - 0.063 13.4 0.1 0.36 10.9 0.1 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 PXF47255.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Zot PF05707.12 PXF47255.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TsaE PF02367.17 PXF47255.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 PXF47255.1 - 0.097 11.9 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin Hydin_ADK PF17213.3 PXF47255.1 - 0.12 12.7 1.5 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 PXF47255.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase LOR PF04525.12 PXF47256.1 - 1.3e-24 86.9 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related WW PF00397.26 PXF47256.1 - 6.3e-08 32.6 5.3 1.2e-07 31.7 5.3 1.5 1 0 0 1 1 1 1 WW domain NtCtMGAM_N PF16863.5 PXF47256.1 - 0.068 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Hydrolase_4 PF12146.8 PXF47257.1 - 4.2e-12 45.9 0.0 7.3e-05 22.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF47257.1 - 1.3e-09 38.1 0.0 9.7e-05 22.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF47257.1 - 4.3e-08 34.0 0.3 2.2e-05 25.1 0.5 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 PXF47257.1 - 0.00085 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PXF47257.1 - 0.001 18.6 0.0 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 PXF47257.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PXF47257.1 - 0.015 15.1 0.0 0.072 12.9 0.0 1.9 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 PXF47257.1 - 0.018 14.9 0.0 0.062 13.2 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase FSH1 PF03959.13 PXF47257.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1057 PF06342.12 PXF47257.1 - 0.085 11.9 0.0 6.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Stealth_CR4 PF17103.5 PXF47257.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 LRAT PF04970.13 PXF47259.1 - 1.7e-14 54.2 3.0 4.8e-13 49.5 3.0 2.1 1 1 0 1 1 1 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 PXF47259.1 - 0.07 12.9 0.8 0.099 12.5 0.8 1.3 1 1 0 1 1 1 0 PPPDE putative peptidase domain SUR7 PF06687.12 PXF47260.1 - 0.0086 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Hydrophobin_2 PF06766.11 PXF47262.1 - 0.04 13.9 3.4 0.22 11.5 1.3 2.1 1 1 1 2 2 2 0 Fungal hydrophobin Goodbye PF17109.5 PXF47262.1 - 1 9.8 6.7 1.6 9.2 0.6 2.6 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF1993 PF09351.10 PXF47262.1 - 1.5 9.0 7.1 0.9 9.7 1.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) SBDS_C PF09377.10 PXF47262.1 - 5.5 7.0 7.8 23 5.0 3.1 2.5 1 1 1 2 2 2 0 SBDS protein C-terminal domain ABC1 PF03109.16 PXF47264.1 - 7.8e-26 90.6 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PXF47264.1 - 4.5e-05 22.9 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain bPH_6 PF10756.9 PXF47264.1 - 0.023 14.8 0.2 11 6.2 0.1 2.8 2 0 0 2 2 2 0 Bacterial PH domain APH PF01636.23 PXF47264.1 - 0.036 14.0 1.7 0.33 10.8 0.0 3.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 PXF47264.1 - 0.084 12.5 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 RIO1 family WaaY PF06176.11 PXF47264.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RskA PF10099.9 PXF47264.1 - 1.8 8.8 6.6 6.8 6.9 6.0 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Glyco_transf_11 PF01531.16 PXF47266.1 - 0.0017 17.6 0.2 0.003 16.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 11 AMP-binding PF00501.28 PXF47267.1 - 1.4e-100 336.9 0.0 1.8e-100 336.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Succ_CoA_lig PF13607.6 PXF47267.1 - 0.072 12.9 0.2 0.29 10.9 0.1 2.1 2 1 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain AMP-binding_C PF13193.6 PXF47267.1 - 0.12 13.4 2.2 0.23 12.4 0.1 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain KCNQ2_u3 PF16642.5 PXF47268.1 - 0.066 14.2 0.0 0.087 13.8 0.0 1.1 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 DZR PF12773.7 PXF47269.1 - 0.02 14.9 0.3 0.036 14.1 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 PXF47269.1 - 0.12 11.7 2.3 0.2 11.0 2.3 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GATase_5 PF13507.6 PXF47270.1 - 4.6e-105 350.4 0.0 6.6e-105 349.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 PXF47270.1 - 7.9e-35 120.3 0.2 3.7e-18 66.1 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 PXF47270.1 - 2.1e-19 69.6 0.0 3.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 PXF47270.1 - 2.3e-11 44.1 0.0 6.5e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 PXF47270.1 - 0.01 16.4 0.1 0.047 14.3 0.0 2.1 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain DnaJ PF00226.31 PXF47271.1 - 5.3e-21 74.5 0.5 9.9e-21 73.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Med29 PF11568.8 PXF47271.1 - 0.054 13.7 0.2 0.1 12.8 0.2 1.5 1 1 0 1 1 1 0 Mediator complex subunit 29 Glyoxalase_3 PF13468.6 PXF47271.1 - 0.24 11.5 2.6 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain TarH PF02203.15 PXF47271.1 - 1.9 8.4 5.6 16 5.4 3.5 2.2 1 1 1 2 2 2 0 Tar ligand binding domain homologue CorA PF01544.18 PXF47272.1 - 1.8e-09 37.4 20.5 3.3e-08 33.2 20.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Methyltransf_3 PF01596.17 PXF47273.1 - 1.8e-17 63.2 0.1 2e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 PXF47273.1 - 0.00014 21.7 0.1 0.00017 21.4 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF47273.1 - 0.00017 22.2 0.2 0.00019 22.1 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF47273.1 - 0.00038 20.3 0.2 0.00039 20.2 0.2 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 PXF47273.1 - 0.0026 18.7 0.1 0.003 18.5 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF47273.1 - 0.0044 16.7 0.1 0.0052 16.5 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 PXF47273.1 - 0.035 13.7 0.0 0.041 13.5 0.0 1.0 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ac81 PF05820.11 PXF47273.1 - 0.042 13.4 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 CDT1 PF08839.11 PXF47274.1 - 0.091 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA replication factor CDT1 like AnfG_VnfG PF03139.15 PXF47275.1 - 0.04 14.0 0.3 0.078 13.1 0.3 1.5 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Mod_r PF07200.13 PXF47275.1 - 0.056 13.5 3.8 2.8 8.0 0.6 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein C2 PF00168.30 PXF47281.1 - 6.9e-05 23.1 0.3 0.00011 22.4 0.3 1.4 1 0 0 1 1 1 1 C2 domain FerI PF08151.12 PXF47281.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain Vps39_2 PF10367.9 PXF47283.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 YhfH PF14149.6 PXF47283.1 - 0.076 13.0 0.8 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2 PF00096.26 PXF47283.1 - 0.12 12.8 0.4 0.12 12.8 0.4 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type AMPK1_CBM PF16561.5 PXF47285.1 - 2.7e-17 62.8 0.2 3.3e-17 62.5 0.2 1.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PHD PF00628.29 PXF47286.1 - 2.1e-08 33.9 4.3 2.1e-08 33.9 4.3 2.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 PXF47286.1 - 0.016 15.5 0.6 0.016 15.5 0.6 2.5 3 0 0 3 3 3 0 PHD-like zinc-binding domain zinc_ribbon_15 PF17032.5 PXF47286.1 - 0.04 14.7 0.4 0.04 14.7 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon family zf-HC5HC2H_2 PF13832.6 PXF47286.1 - 0.044 14.0 0.5 0.044 14.0 0.5 1.8 2 0 0 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 PXF47286.1 - 0.36 10.9 20.3 0.039 14.0 0.9 3.6 3 1 0 3 3 3 0 Double zinc ribbon C1_2 PF03107.16 PXF47286.1 - 0.51 10.7 13.6 0.24 11.7 0.3 3.2 3 0 0 3 3 3 0 C1 domain Zn_ribbon_17 PF17120.5 PXF47286.1 - 5.5 6.7 17.3 6.5 6.5 1.5 3.6 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 PXF47286.1 - 7 6.3 9.2 0.18 11.4 0.8 2.6 2 0 0 2 2 2 0 PHD-finger AMPK1_CBM PF16561.5 PXF47287.1 - 9e-18 64.3 0.6 1.3e-17 63.7 0.6 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 PXF47287.1 - 0.12 13.0 0.6 0.21 12.2 0.6 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) FKBP_C PF00254.28 PXF47288.1 - 9.7e-14 51.5 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lipase_3 PF01764.25 PXF47289.1 - 5.1e-14 52.3 0.0 8.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) bZIP_1 PF00170.21 PXF47289.1 - 0.0012 18.9 10.6 0.0012 18.9 10.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor Ribo_biogen_C PF04034.13 PXF47291.1 - 9.1e-51 170.9 0.0 1.2e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 PXF47291.1 - 7.6e-12 44.8 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI zf-HIT PF04438.16 PXF47292.1 - 4.9e-07 29.5 14.2 8.1e-07 28.8 14.2 1.3 1 0 0 1 1 1 1 HIT zinc finger PDCD7 PF16021.5 PXF47292.1 - 1.2 8.2 12.7 0.063 12.4 5.7 1.9 1 1 1 2 2 2 0 Programmed cell death protein 7 YacG PF03884.14 PXF47292.1 - 2.2 8.1 7.0 5 6.9 7.0 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG ANTH PF07651.16 PXF47293.1 - 7.8e-34 116.9 0.4 1.2e-33 116.3 0.0 1.4 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 PXF47293.1 - 2.7e-06 27.4 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ENTH domain MIR PF02815.19 PXF47293.1 - 0.35 10.7 3.3 0.7 9.7 3.3 1.4 1 0 0 1 1 1 0 MIR domain Adaptin_N PF01602.20 PXF47294.1 - 1.6e-108 363.5 6.7 2.2e-108 363.1 6.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 PXF47294.1 - 3.9e-45 153.7 0.0 1.6e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 PXF47294.1 - 8.9e-26 90.3 0.0 2.7e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 PXF47294.1 - 2e-15 56.9 10.2 1.2e-06 28.8 0.1 5.7 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 PXF47294.1 - 1e-14 54.9 8.8 2.3e-07 31.0 0.6 4.1 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PXF47294.1 - 4.9e-05 23.7 13.6 0.0034 17.9 1.7 5.1 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 PXF47294.1 - 0.005 17.0 15.6 6.6 7.3 0.1 7.4 9 0 0 9 9 9 1 HEAT repeat U3snoRNP10 PF12397.8 PXF47294.1 - 0.033 14.5 5.5 0.12 12.8 1.1 3.6 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 HEAT_PBS PF03130.16 PXF47294.1 - 0.062 14.0 5.5 29 5.7 0.6 5.0 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat CLASP_N PF12348.8 PXF47294.1 - 0.14 11.7 1.6 0.61 9.6 0.3 2.5 2 0 0 2 2 2 0 CLASP N terminal FHA PF00498.26 PXF47295.1 - 1.8e-06 28.2 0.0 4.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 PXF47295.1 - 0.0096 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 PXF47295.1 - 0.017 15.5 0.0 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 PXF47295.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF4612 PF15389.6 PXF47295.1 - 0.067 14.2 4.5 0.26 12.3 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) MarR_2 PF12802.7 PXF47296.1 - 0.11 12.5 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 MarR family LRR_2 PF07723.13 PXF47297.1 - 8 7.3 6.7 1.8 9.4 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat DHHC PF01529.20 PXF47298.1 - 4e-30 104.6 7.4 4.8e-30 104.4 7.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4577 PF15145.6 PXF47298.1 - 4.6 7.3 4.6 1.3 9.0 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) TIG PF01833.24 PXF47299.1 - 4.2e-16 58.8 6.3 2e-09 37.4 0.1 2.6 2 0 0 2 2 2 2 IPT/TIG domain PA14 PF07691.12 PXF47299.1 - 0.0026 17.6 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 PA14 domain TPT PF03151.16 PXF47301.1 - 3.8e-88 295.6 18.5 1.5e-87 293.6 18.5 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF47301.1 - 4.2e-12 46.4 32.7 2.4e-07 31.0 12.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLH PF00395.20 PXF47301.1 - 0.03 14.3 0.3 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 S-layer homology domain Amino_oxidase PF01593.24 PXF47302.1 - 5.3e-48 164.4 0.5 2.8e-18 66.4 0.0 4.5 5 0 0 5 5 5 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF47302.1 - 1.8e-10 40.9 0.0 4.6e-09 36.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PXF47302.1 - 4.2e-06 26.2 0.1 7.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PXF47302.1 - 1.2e-05 25.1 1.4 2.9e-05 23.8 1.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF47302.1 - 4.9e-05 22.6 0.5 8.7e-05 21.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PXF47302.1 - 7.8e-05 22.0 0.0 0.00027 20.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF47302.1 - 0.00013 21.1 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 PXF47302.1 - 0.00059 18.7 0.2 0.0012 17.7 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 PXF47302.1 - 0.0026 17.1 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF47302.1 - 0.006 16.6 0.1 0.022 14.8 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF4032 PF13224.6 PXF47302.1 - 0.029 14.2 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) FAD_oxidored PF12831.7 PXF47302.1 - 0.042 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 PXF47302.1 - 0.043 14.4 0.6 0.14 12.7 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PXF47302.1 - 0.085 12.1 0.4 0.17 11.1 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_16 PF00722.21 PXF47303.1 - 2.2e-15 56.6 0.5 3.4e-15 56.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BUD22 PF09073.10 PXF47303.1 - 0.09 12.1 7.5 0.13 11.6 7.5 1.1 1 0 0 1 1 1 0 BUD22 RRM_DME PF15628.6 PXF47303.1 - 0.13 12.5 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 RRM in Demeter DUF3246 PF11596.8 PXF47303.1 - 2.8 7.3 9.0 0.53 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Osteopontin PF00865.18 PXF47303.1 - 8.2 5.8 16.1 0.24 10.9 5.7 2.1 2 0 0 2 2 2 0 Osteopontin Alba PF01918.21 PXF47304.1 - 4.2e-06 26.5 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alba SET PF00856.28 PXF47305.1 - 0.0062 16.9 4.7 0.12 12.8 0.0 3.5 2 2 0 2 2 2 1 SET domain RSN1_7TM PF02714.15 PXF47306.1 - 7.4e-53 179.6 16.1 7.4e-53 179.6 16.1 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PXF47306.1 - 3.4e-37 127.6 1.3 3.4e-37 127.6 1.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PXF47306.1 - 1.1e-15 58.4 0.2 1.8e-15 57.6 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter UPF0004 PF00919.20 PXF47306.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF2208 PF09973.9 PXF47306.1 - 0.21 11.2 11.5 0.038 13.6 5.0 2.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2208) WD40 PF00400.32 PXF47307.1 - 1.9e-07 31.6 10.4 0.27 12.2 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF4667 PF15700.5 PXF47307.1 - 0.0017 18.5 27.8 0.089 12.9 13.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4667) Secretin_N_2 PF07655.13 PXF47307.1 - 0.18 12.4 23.3 0.82 10.3 12.6 2.9 3 0 0 3 3 3 0 Secretin N-terminal domain ATG16 PF08614.11 PXF47307.1 - 0.22 11.7 9.4 0.034 14.4 1.9 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CCDC24 PF15669.5 PXF47307.1 - 6.3 6.6 17.3 4.6 7.1 6.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family WD40 PF00400.32 PXF47308.1 - 3.1e-19 69.0 17.8 3e-05 24.7 0.1 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47308.1 - 1.2e-06 28.7 0.7 0.073 13.4 0.2 4.5 2 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4175 PF13779.6 PXF47309.1 - 0.0057 14.6 0.2 0.0068 14.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) MSP7_C PF12948.7 PXF47312.1 - 0.79 10.4 5.3 1.4 9.6 3.0 2.1 1 1 1 2 2 2 0 MSP7-like protein C-terminal domain MTS PF05175.14 PXF47314.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PXF47314.1 - 1.8e-06 28.5 0.0 3.8e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF47314.1 - 4.4e-06 26.6 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF47314.1 - 5.2e-06 26.2 0.0 7.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Spermine_synth PF01564.17 PXF47314.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_11 PF08241.12 PXF47314.1 - 0.00015 22.4 0.0 0.00027 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF47314.1 - 0.00032 20.5 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PXF47314.1 - 0.0056 17.7 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF47314.1 - 0.0084 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.16 PXF47314.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain UPF0020 PF01170.18 PXF47314.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_30 PF05430.11 PXF47314.1 - 0.083 12.8 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase Met_10 PF02475.16 PXF47314.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HEPPP_synt_1 PF07307.11 PXF47314.1 - 0.23 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 PfkB PF00294.24 PXF47315.1 - 6.1e-40 137.4 0.0 1e-38 133.4 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PHD PF00628.29 PXF47316.1 - 8.3e-13 48.0 5.9 1.2e-12 47.5 5.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PXF47316.1 - 0.0058 16.2 1.5 0.0058 16.2 1.5 1.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 PXF47316.1 - 0.016 14.8 1.4 0.035 13.7 1.4 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 PXF47316.1 - 0.03 14.6 0.2 0.05 13.8 0.2 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 PXF47316.1 - 0.061 13.7 7.0 0.098 13.0 7.0 1.3 1 0 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 PXF47316.1 - 0.38 11.1 3.8 0.2 12.0 1.3 1.8 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 PXF47316.1 - 0.47 10.6 5.5 0.1 12.7 1.9 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 PXF47316.1 - 1.7 8.8 5.2 4.5 7.4 5.2 1.8 1 1 0 1 1 1 0 PHD-finger PPP5 PF08321.12 PXF47317.1 - 1.9e-26 92.2 0.0 7.2e-26 90.3 0.0 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 PXF47317.1 - 2.4e-26 93.5 0.1 5e-26 92.5 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 PXF47317.1 - 1.9e-11 43.3 1.6 0.00027 20.6 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF47317.1 - 5e-08 32.5 3.1 0.0042 17.1 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF47317.1 - 0.00025 21.3 2.1 0.17 12.2 0.1 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 PXF47317.1 - 0.0022 18.3 0.5 0.0085 16.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF47317.1 - 0.0027 18.2 0.4 0.051 14.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF47317.1 - 0.0028 17.3 0.2 0.056 13.1 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 PXF47317.1 - 0.016 16.0 0.7 2.1 9.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PXF47317.1 - 0.031 14.9 0.6 0.27 11.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF47317.1 - 0.051 13.6 1.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF47317.1 - 0.16 12.3 0.9 3.3 8.2 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF47317.1 - 0.25 12.1 1.9 0.8 10.5 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5060 PF16586.5 PXF47318.1 - 6.9e-17 61.6 2.4 1.1e-16 60.9 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF5060) Collagen_bind_2 PF12904.7 PXF47318.1 - 0.00015 21.7 0.0 0.0004 20.3 0.0 1.8 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase DUF2500 PF10694.9 PXF47318.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) HTH_Tnp_Tc5 PF03221.16 PXF47319.1 - 6.2e-06 26.1 0.1 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 PXF47319.1 - 3.5e-05 23.3 0.5 6.8e-05 22.4 0.2 1.7 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 PXF47319.1 - 0.00074 19.2 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 PXF47319.1 - 0.0038 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Trans_reg_C PF00486.28 PXF47319.1 - 0.02 14.9 0.6 0.035 14.2 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DDE_1 PF03184.19 PXF47321.1 - 9.5e-24 84.0 0.3 5.2e-23 81.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF47321.1 - 3.2e-07 30.3 1.3 6.3e-07 29.3 1.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SNF5 PF04855.12 PXF47322.1 - 7.6e-15 55.3 4.2 2e-07 31.1 0.6 3.1 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 DUF1857 PF08982.11 PXF47322.1 - 0.01 15.7 0.1 0.031 14.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Peptidase_S8 PF00082.22 PXF47323.1 - 1.5e-29 103.2 4.4 2.6e-29 102.4 4.4 1.3 1 0 0 1 1 1 1 Subtilase family RalF_SCD PF18248.1 PXF47323.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain PQ-loop PF04193.14 PXF47324.1 - 7.7e-19 67.2 5.5 1.2e-09 37.8 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Bax1-I PF01027.20 PXF47324.1 - 0.44 10.3 18.5 0.027 14.3 11.7 1.9 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 PXF47325.1 - 1.3e-15 57.5 12.4 0.0046 17.8 0.0 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47325.1 - 9.4e-14 51.5 0.0 1.7e-08 34.6 0.0 4.8 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF47325.1 - 0.005 16.7 0.0 0.023 14.6 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SARS_X4 PF08779.10 PXF47325.1 - 0.028 14.6 0.0 0.14 12.4 0.0 2.1 3 0 0 3 3 3 0 SARS coronavirus X4 like Ge1_WD40 PF16529.5 PXF47325.1 - 0.039 12.9 0.0 4.4 6.2 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 PXF47325.1 - 0.052 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain ASC PF00858.24 PXF47326.1 - 8.6e-05 21.7 0.1 0.069 12.1 0.1 2.3 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel Eapp_C PF10238.9 PXF47327.1 - 2.8e-26 92.4 13.6 1e-18 67.9 2.5 2.5 2 1 1 3 3 3 2 E2F-associated phosphoprotein DUF1759 PF03564.15 PXF47328.1 - 0.0073 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) ClpS PF02617.17 PXF47330.1 - 6.4e-13 48.3 0.5 8.8e-13 47.8 0.5 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UPRTase PF14681.6 PXF47331.1 - 2.2e-47 161.2 0.0 4e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 PXF47331.1 - 1.5e-44 152.1 0.4 3.1e-44 151.1 0.4 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PXF47331.1 - 6.9e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 PXF47331.1 - 0.0039 17.1 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 PXF47331.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 PXF47331.1 - 0.024 14.8 0.0 0.064 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 PXF47331.1 - 0.091 12.4 0.5 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_17 PF13207.6 PXF47331.1 - 0.099 13.1 1.2 1 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PXF47331.1 - 0.13 12.2 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 NTPase BACK PF07707.15 PXF47332.1 - 8.6e-11 41.9 0.3 1.7e-10 40.9 0.3 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 PXF47332.1 - 6.4e-10 39.3 0.6 6.8e-07 29.5 0.3 2.4 2 0 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 PXF47332.1 - 3.9e-07 30.2 0.0 8.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 MATH domain Transglut_prok PF09017.10 PXF47332.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Microbial transglutaminase bZIP_1 PF00170.21 PXF47334.1 - 0.023 14.8 9.2 0.05 13.7 9.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 PXF47334.1 - 0.094 12.8 9.7 0.21 11.7 9.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Phlebovirus_NSM PF07246.11 PXF47334.1 - 0.13 11.6 4.1 0.18 11.2 4.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Eapp_C PF10238.9 PXF47334.1 - 0.25 11.4 6.5 0.41 10.7 6.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Glyco_transf_7N PF13733.6 PXF47334.1 - 0.34 10.6 3.2 0.53 9.9 3.2 1.4 1 1 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 GET2 PF08690.10 PXF47334.1 - 1.1 8.9 10.6 1.5 8.4 10.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 PXF47334.1 - 4.9 7.1 18.3 6.3 6.7 18.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 PXF47334.1 - 6.5 5.2 14.5 8.5 4.8 14.5 1.1 1 0 0 1 1 1 0 Macoilin family Chalcone_2 PF16035.5 PXF47335.1 - 6.3e-07 29.4 0.5 0.0078 16.0 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 PXF47335.1 - 6.6e-07 29.6 0.0 0.0034 17.5 0.0 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 PXF47335.1 - 0.0025 17.3 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 1 Chalcone-flavanone isomerase Acyltransferase PF01553.21 PXF47336.1 - 1.4e-28 99.2 0.0 2.2e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UEV PF05743.13 PXF47336.1 - 0.015 15.1 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 UEV domain SUR7 PF06687.12 PXF47336.1 - 0.074 12.7 1.0 0.14 11.8 1.0 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF374 PF04028.13 PXF47336.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Mito_carr PF00153.27 PXF47337.1 - 4e-50 167.7 4.5 2.1e-22 78.8 0.6 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 PXF47337.1 - 0.042 14.0 3.1 0.062 13.4 0.1 2.4 2 1 1 3 3 3 0 Threonine/Serine exporter, ThrE Serine_protease PF18405.1 PXF47337.1 - 0.069 12.3 0.1 0.19 10.8 0.1 1.8 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Pkinase PF00069.25 PXF47338.1 - 1.8e-76 257.0 0.0 2.1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47338.1 - 2.3e-30 105.8 0.0 4.8e-30 104.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF47338.1 - 3.6e-06 26.5 0.0 3.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF47338.1 - 1.6e-05 24.0 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PXF47338.1 - 0.019 14.0 0.2 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PI3_PI4_kinase PF00454.27 PXF47339.1 - 2e-30 106.4 0.0 2.8e-27 96.1 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 PXF47339.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) AsnA PF03590.15 PXF47340.1 - 0.05 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase OSCP PF00213.18 PXF47343.1 - 3.7e-39 134.6 0.3 4.4e-39 134.4 0.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Knl1_RWD_C PF18210.1 PXF47343.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain SBP_bac_3 PF00497.20 PXF47343.1 - 0.072 12.5 0.4 0.15 11.4 0.2 1.6 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 GidB PF02527.15 PXF47344.1 - 1.3e-41 141.9 0.0 1.7e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 PXF47344.1 - 6e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PXF47344.1 - 0.00044 20.1 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF47344.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 PXF47345.1 - 0.002 19.1 0.0 0.01 16.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CTP_transf_like PF01467.26 PXF47346.1 - 1e-18 67.9 0.0 1.3e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like NAM-associated PF14303.6 PXF47347.1 - 3.1e-13 50.8 1.6 4.7e-13 50.2 1.6 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain PNKP-ligase_C PF16536.5 PXF47347.1 - 0.032 14.5 0.9 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 PNKP adenylyltransferase domain, C-terminal region Orn_Arg_deC_N PF02784.16 PXF47348.1 - 9e-72 241.4 0.0 1.1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PXF47348.1 - 1.2e-09 38.3 0.0 1.3e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 PXF47348.1 - 0.00052 19.5 0.0 0.00094 18.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BBS2_C PF14782.6 PXF47348.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Metallophos PF00149.28 PXF47349.1 - 1.1e-14 55.5 1.1 1.3e-14 55.2 1.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF47349.1 - 0.00087 19.5 0.6 0.022 14.9 0.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Gemin6 PF06372.12 PXF47351.1 - 7.4e-05 22.3 0.0 0.0051 16.4 0.0 2.1 2 0 0 2 2 2 2 Gemin6 protein DUF2642 PF10842.8 PXF47351.1 - 0.013 15.3 0.1 3.4 7.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2642) BBIP10 PF14777.6 PXF47352.1 - 0.032 13.8 0.2 0.088 12.4 0.1 1.7 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 LRR_6 PF13516.6 PXF47353.1 - 1.6e-15 55.7 2.7 0.058 13.5 0.0 8.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 PXF47353.1 - 1.3e-12 47.7 0.7 0.03 14.7 0.0 6.0 2 1 6 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PXF47353.1 - 1.3e-10 41.0 1.9 4.1e-10 39.4 1.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF47353.1 - 3.1e-09 36.5 2.7 1.6e-08 34.2 2.7 2.3 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 PXF47353.1 - 4.8e-05 23.4 11.5 1.2 10.0 0.0 6.9 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 PXF47353.1 - 0.00026 20.7 1.8 11 5.8 0.0 5.6 5 1 1 6 6 6 2 Leucine rich repeat DUF1699 PF08004.11 PXF47353.1 - 0.02 14.6 0.4 24 4.6 0.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF1699) IMS PF00817.20 PXF47354.1 - 3.4e-44 150.5 0.2 9.2e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 PXF47354.1 - 2.2e-06 28.4 0.1 1.1e-05 26.1 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PXF47354.1 - 3.9e-05 23.7 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 PXF47354.1 - 0.041 14.1 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus FliH PF02108.16 PXF47354.1 - 0.063 13.3 0.4 0.17 11.9 0.4 1.7 1 0 0 1 1 1 0 Flagellar assembly protein FliH ATP-synt_F PF01990.17 PXF47355.1 - 1.3e-32 111.9 0.1 1.5e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit TCR PF03638.15 PXF47356.1 - 4.2e-25 87.8 54.8 1.1e-12 48.0 22.6 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Bap31 PF05529.12 PXF47357.1 - 3.2e-20 72.4 2.2 3.7e-20 72.2 2.2 1.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Cadherin_C_2 PF16492.5 PXF47357.1 - 2.8 8.7 4.4 2.5 8.9 0.4 2.3 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal DUF4124 PF13511.6 PXF47358.1 - 0.013 15.9 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Pre-PUA PF17832.1 PXF47359.1 - 2.2e-23 82.7 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 PXF47359.1 - 4.5e-16 58.6 1.0 7.6e-16 57.8 1.0 1.4 1 0 0 1 1 1 1 PUA domain SH3_6 PF12913.7 PXF47359.1 - 0.033 13.8 0.1 0.096 12.3 0.0 1.8 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) eIF-1a PF01176.19 PXF47361.1 - 4.7e-25 87.2 0.0 6.5e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 PXF47361.1 - 0.00024 20.8 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 PXF47361.1 - 0.086 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain DUF745 PF05335.13 PXF47362.1 - 2.7e-05 24.0 10.3 2.7e-05 24.0 10.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF745) Fib_alpha PF08702.10 PXF47362.1 - 0.00052 20.2 5.0 0.00052 20.2 5.0 2.3 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 PXF47362.1 - 0.0039 17.5 20.5 0.006 16.9 17.9 2.7 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rab5-bind PF09311.11 PXF47362.1 - 0.0092 15.4 15.8 0.0092 15.4 15.8 2.1 3 0 0 3 3 3 1 Rabaptin-like protein MbeD_MobD PF04899.12 PXF47362.1 - 0.01 15.9 7.5 0.1 12.7 5.1 2.9 2 0 0 2 2 2 0 MbeD/MobD like COG5 PF10392.9 PXF47362.1 - 0.019 15.1 5.3 0.019 15.1 5.3 2.6 3 0 0 3 3 3 0 Golgi transport complex subunit 5 CLZ PF16526.5 PXF47362.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 PXF47362.1 - 0.23 11.6 20.6 0.023 14.8 11.7 3.3 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 PXF47362.1 - 0.52 9.8 14.4 1.1 8.8 11.0 2.5 2 1 0 2 2 2 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 PXF47362.1 - 0.58 10.1 22.8 0.36 10.8 7.7 3.4 2 1 1 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.7 PXF47362.1 - 2.2 8.4 28.3 0.12 12.5 21.4 2.4 3 0 0 3 3 3 0 Tropomyosin like Noelin-1 PF12308.8 PXF47362.1 - 3 7.9 7.4 10 6.1 1.1 3.1 2 1 1 3 3 3 0 Neurogenesis glycoprotein AAA_13 PF13166.6 PXF47362.1 - 3.2 6.3 16.1 8.2 4.9 16.0 1.6 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.11 PXF47362.1 - 3.6 7.9 6.6 6.2 7.1 3.9 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 PXF47362.1 - 3.6 8.0 14.1 9.5 6.7 3.3 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 PXF47362.1 - 3.9 7.5 20.8 1.3 9.0 17.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1192 PF06698.11 PXF47362.1 - 4.7 7.4 13.0 17 5.5 2.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.12 PXF47362.1 - 5.6 7.5 7.2 8.5 6.9 0.2 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 PXF47362.1 - 5.9 6.9 12.3 25 4.9 10.9 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 PXF47362.1 - 6.8 6.8 10.5 2.1e+02 2.0 9.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sulfotransfer_3 PF13469.6 PXF47364.1 - 1.1e-05 26.0 0.0 0.0025 18.2 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PXF47364.1 - 0.0026 17.3 0.1 0.011 15.2 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase domain DUF4667 PF15700.5 PXF47364.1 - 0.016 15.3 0.4 0.022 14.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) ETX_MTX2 PF03318.13 PXF47364.1 - 0.54 10.0 2.8 5.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 GP40 PF11025.8 PXF47365.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium FKBP_C PF00254.28 PXF47366.1 - 3.4e-32 110.6 0.0 4.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LPAM_1 PF08139.12 PXF47366.1 - 0.95 10.1 4.8 1.8 9.2 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site TFIID-31kDa PF02291.15 PXF47367.1 - 4.7e-38 130.0 0.0 8.8e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PXF47367.1 - 0.00037 20.4 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 PXF47367.1 - 0.0058 17.0 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Peptidase_A22B PF04258.13 PXF47368.1 - 4.8e-78 262.5 5.1 6.6e-78 262.1 5.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase EF-hand_1 PF00036.32 PXF47369.1 - 7.1e-39 128.5 11.2 2.7e-09 35.9 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PXF47369.1 - 7.9e-33 112.7 1.2 2.5e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PXF47369.1 - 1.7e-31 105.4 4.5 1.6e-09 36.9 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PXF47369.1 - 1.8e-30 104.6 11.5 2.8e-12 46.3 0.4 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PXF47369.1 - 2.7e-30 102.5 9.4 7.7e-08 31.5 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PXF47369.1 - 2.9e-16 59.5 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PXF47369.1 - 9.3e-09 35.2 0.5 0.0023 17.8 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PXF47369.1 - 1.5e-08 34.9 0.0 0.0045 17.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PXF47369.1 - 1.1e-06 28.6 0.6 0.033 14.2 0.1 3.1 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 PXF47369.1 - 3.3e-06 27.2 4.1 0.0041 17.3 0.7 3.1 1 1 3 4 4 4 3 Dockerin type I domain EF-hand_11 PF08976.11 PXF47369.1 - 1.2e-05 26.1 0.0 0.028 15.3 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain TerB PF05099.13 PXF47369.1 - 0.00017 21.5 0.2 0.39 10.7 0.0 2.5 2 1 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_14 PF17959.1 PXF47369.1 - 0.00053 20.3 0.2 0.37 11.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain RNA_pol_Rpb4 PF03874.16 PXF47369.1 - 0.00095 19.5 0.7 0.22 11.9 0.2 2.7 3 1 0 3 3 2 1 RNA polymerase Rpb4 Caleosin PF05042.13 PXF47369.1 - 0.0041 17.0 0.5 1.2 9.1 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein YqeY PF09424.10 PXF47369.1 - 0.012 15.7 1.5 0.1 12.7 0.5 2.1 1 1 1 2 2 2 0 Yqey-like protein DUF4604 PF15377.6 PXF47369.1 - 0.014 15.8 0.1 0.019 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Mu-like_Pro PF10123.9 PXF47369.1 - 0.032 13.8 0.1 0.035 13.7 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein VbhA PF18495.1 PXF47369.1 - 0.032 14.1 0.6 6.2 6.8 0.1 3.5 4 1 0 4 4 3 0 Antitoxin VbhA Poly_export PF02563.16 PXF47369.1 - 0.046 14.0 0.0 0.76 10.0 0.0 2.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 PXF47369.1 - 0.07 13.2 0.3 5.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 UBA_6 PF18039.1 PXF47369.1 - 0.098 12.6 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain DUF5580 PF17743.1 PXF47369.1 - 0.12 10.9 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) ApbA_C PF08546.11 PXF47369.1 - 0.15 12.3 0.3 19 5.4 0.0 2.2 1 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Lactamase_B_3 PF13483.6 PXF47370.1 - 4.1e-24 85.3 0.0 7.3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PXF47370.1 - 2.3e-07 30.5 0.1 3.3e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PLRV_ORF5 PF01690.17 PXF47370.1 - 0.27 9.9 1.4 0.4 9.3 1.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ResIII PF04851.15 PXF47371.1 - 6.5e-15 55.5 0.0 1.4e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PXF47371.1 - 8.9e-15 55.0 0.1 8.4e-14 51.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF47371.1 - 1.6e-11 44.3 0.0 6.4e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 PXF47371.1 - 0.034 13.6 0.0 9.6 5.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein ELO PF01151.18 PXF47372.1 - 1.3e-49 169.0 24.7 1.5e-49 168.8 24.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Tic22 PF04278.12 PXF47373.1 - 7.8e-24 84.4 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Tic22-like family HPIP PF15226.6 PXF47373.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Pribosyltran PF00156.27 PXF47374.1 - 4.2e-19 68.6 0.0 5.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SPOUT_MTase PF02590.17 PXF47375.1 - 2.7e-28 98.9 0.0 4.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase NTPase_1 PF03266.15 PXF47375.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.4 1 1 0 1 1 1 0 NTPase P-mevalo_kinase PF04275.14 PXF47375.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase Methyltrn_RNA_2 PF04013.12 PXF47375.1 - 0.086 12.5 0.1 0.43 10.2 0.2 1.9 1 1 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase NUDE_C PF04880.13 PXF47376.1 - 0.25 11.8 4.6 0.31 11.5 4.6 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region AAA_lid_2 PF17863.1 PXF47377.1 - 2.9e-13 49.5 6.0 4.7e-13 48.8 0.6 2.9 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase PF01078.21 PXF47377.1 - 5.1e-12 45.6 0.0 1.4e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 PXF47377.1 - 1.5e-11 44.9 0.0 6.6e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain MCM PF00493.23 PXF47377.1 - 6.1e-09 35.3 0.0 2e-08 33.6 0.0 1.8 1 1 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 PXF47377.1 - 2.1e-07 31.0 0.0 1.2e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) VWA PF00092.28 PXF47377.1 - 1.3e-06 28.7 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 PXF47377.1 - 3.1e-05 23.7 0.0 0.039 13.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain VWA_3 PF13768.6 PXF47377.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain GEN1_C PF18380.1 PXF47377.1 - 0.11 13.4 7.2 0.23 12.3 4.9 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Mito_fiss_reg PF05308.11 PXF47377.1 - 0.77 9.8 12.3 0.28 11.2 2.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator PAXIP1_C PF15364.6 PXF47377.1 - 0.95 9.8 8.8 2.2 8.6 8.8 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein CCDC53 PF10152.9 PXF47377.1 - 4.7 7.6 10.5 0.55 10.7 2.6 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CAP_N PF01213.19 PXF47377.1 - 6.5 6.1 10.0 0.1 12.0 0.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TerC PF03741.16 PXF47378.1 - 1.2e-48 165.2 12.4 2e-48 164.5 12.4 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family SQS_PSY PF00494.19 PXF47379.1 - 3.2e-32 112.1 0.3 3.9e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Syntaxin-18_N PF10496.9 PXF47380.1 - 4.8e-06 26.7 0.2 0.00011 22.4 0.0 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus GNT-I PF03071.15 PXF47381.1 - 0.01 14.6 0.0 0.08 11.7 0.0 1.9 2 0 0 2 2 2 0 GNT-I family DUF5484 PF17583.2 PXF47381.1 - 2.1 8.1 5.2 12 5.7 1.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5484) URO-D PF01208.17 PXF47382.1 - 3.6e-114 381.5 0.0 4.2e-114 381.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Acyltransferase PF01553.21 PXF47384.1 - 4.2e-15 55.6 0.0 9.2e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Ost5 PF05251.12 PXF47384.1 - 0.23 11.8 1.1 0.79 10.0 0.2 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF639 PF04842.12 PXF47385.1 - 5e-11 42.5 0.0 8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) PRT_C PF08372.10 PXF47385.1 - 0.0034 17.2 2.1 0.64 9.8 0.2 2.5 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal EF-hand_1 PF00036.32 PXF47385.1 - 0.0039 16.6 0.0 0.0096 15.4 0.0 1.7 1 0 0 1 1 1 1 EF hand Reticulon PF02453.17 PXF47385.1 - 0.0052 16.8 5.1 0.0088 16.0 5.1 1.3 1 0 0 1 1 1 1 Reticulon EF-hand_8 PF13833.6 PXF47385.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair GRAM PF02893.20 PXF47385.1 - 0.056 13.3 0.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 GRAM domain EF-hand_6 PF13405.6 PXF47385.1 - 0.06 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Pex24p PF06398.11 PXF47385.1 - 0.1 11.5 1.0 0.25 10.3 1.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin EF-hand_5 PF13202.6 PXF47385.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Lin0512_fam PF09585.10 PXF47386.1 - 1.4e-34 118.5 0.4 1.6e-34 118.3 0.4 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) DUF993 PF06187.11 PXF47387.1 - 0.00079 18.4 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF993) Bac_rhamnosid_C PF17390.2 PXF47387.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain DUF3475 PF11961.8 PXF47389.1 - 0.15 12.1 0.7 0.28 11.3 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3475) Glutaredoxin2_C PF04399.13 PXF47391.1 - 1.1e-33 115.8 0.0 1.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 PXF47391.1 - 2.1e-10 40.9 0.0 5.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF47391.1 - 4.6e-05 23.6 0.0 8.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PXF47391.1 - 0.0083 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin LANC_like PF05147.13 PXF47392.1 - 4.7e-44 150.4 0.0 1e-43 149.3 0.0 1.5 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein HIG_1_N PF04588.13 PXF47392.1 - 0.0038 17.4 1.1 24 5.3 0.0 3.8 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Glyco_hydro_127 PF07944.12 PXF47392.1 - 0.0074 14.8 0.1 0.011 14.2 0.1 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 TPR_6 PF13174.6 PXF47392.1 - 0.013 16.1 0.9 12 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MAPEG PF01124.18 PXF47393.1 - 9.1e-10 38.5 4.0 1.1e-09 38.2 4.0 1.2 1 0 0 1 1 1 1 MAPEG family Na_H_Exchanger PF00999.21 PXF47394.1 - 7.6e-46 156.6 42.6 1.2e-45 156.0 42.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mut7-C PF01927.16 PXF47395.1 - 8.9e-21 74.5 1.6 1.2e-20 74.1 0.3 1.9 1 1 0 1 1 1 1 Mut7-C RNAse domain Exo_endo_phos PF03372.23 PXF47395.1 - 1.1e-14 54.5 0.1 9.5e-09 35.1 0.0 2.4 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PXF47395.1 - 0.15 11.9 0.4 18 5.2 0.0 3.3 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Antimicrobial25 PF16839.5 PXF47395.1 - 0.45 10.6 5.1 8.6 6.5 0.1 2.8 2 1 0 2 2 2 0 Nematode antimicrobial peptide PALP PF00291.25 PXF47396.1 - 3.2e-76 256.6 4.6 4.3e-76 256.1 4.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 PXF47396.1 - 5.9e-43 144.6 0.1 9.1e-21 73.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase FGGY_C PF02782.16 PXF47397.1 - 8e-34 117.1 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 PXF47397.1 - 1.3e-20 74.0 0.0 8.3e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 PXF47397.1 - 0.0043 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Cauli_AT PF03233.13 PXF47399.1 - 0.038 13.9 1.3 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Aphid transmission protein Flot PF15975.5 PXF47399.1 - 0.049 13.8 0.8 0.093 12.9 0.8 1.5 1 0 0 1 1 1 0 Flotillin FlxA PF14282.6 PXF47399.1 - 0.2 11.7 3.8 16 5.5 0.1 3.9 2 1 1 4 4 4 0 FlxA-like protein CLZ PF16526.5 PXF47399.1 - 0.4 11.1 10.6 4.8 7.6 0.0 4.5 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 PXF47399.1 - 0.57 10.5 0.1 0.57 10.5 0.1 4.3 4 0 0 4 4 4 0 ABC transporter C-terminal domain SNase PF00565.17 PXF47400.1 - 4.8e-12 46.3 0.0 7.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SBDS PF01172.18 PXF47401.1 - 2.2e-30 104.5 0.7 4.2e-30 103.6 0.7 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 PXF47401.1 - 3.6e-30 104.4 0.3 5.7e-30 103.7 0.3 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF2267 PF10025.9 PXF47401.1 - 0.068 13.5 0.8 0.39 11.0 0.7 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) 2-Hacid_dh_C PF02826.19 PXF47401.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Brix PF04427.18 PXF47402.1 - 7e-36 124.1 0.0 9.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glucosamine_iso PF01182.20 PXF47403.1 - 1e-61 208.7 0.0 1.2e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF202 PF02656.15 PXF47404.1 - 1.4e-08 35.1 2.2 5.1e-08 33.2 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MerT PF02411.15 PXF47404.1 - 0.032 14.3 0.2 0.048 13.7 0.2 1.3 1 0 0 1 1 1 0 MerT mercuric transport protein GOLD_2 PF13897.6 PXF47404.1 - 0.079 13.5 0.2 0.12 12.9 0.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4199 PF13858.6 PXF47404.1 - 0.095 13.1 3.2 0.15 12.5 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) SARAF PF06682.12 PXF47405.1 - 1.8e-32 113.3 0.0 2.3e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Kinesin PF00225.23 PXF47406.1 - 5.3e-87 291.8 0.0 5.3e-87 291.8 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF47406.1 - 3.6e-11 43.2 0.0 9.1e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding SlyX PF04102.12 PXF47406.1 - 0.37 11.4 10.3 4 8.1 1.4 4.8 4 1 1 5 5 5 0 SlyX DivIC PF04977.15 PXF47406.1 - 4.9 7.0 9.8 19 5.1 0.0 3.9 2 1 3 5 5 5 0 Septum formation initiator Peptidase_M16 PF00675.20 PXF47406.1 - 6.9 6.6 7.5 2.1 8.3 1.1 2.6 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) NodZ PF05830.11 PXF47407.1 - 1.5e-08 33.9 0.0 0.00064 18.6 0.0 2.4 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PXF47407.1 - 0.14 10.8 0.0 0.83 8.2 0.0 2.1 2 1 0 2 2 2 0 Xyloglucan fucosyltransferase Meth_synt_2 PF01717.18 PXF47408.1 - 8.7e-139 462.3 0.0 3.1e-137 457.2 0.0 2.6 3 1 0 3 3 3 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 PXF47408.1 - 6.7e-88 295.2 0.0 9.2e-83 278.3 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 PXF47408.1 - 0.09 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain Proteasome PF00227.26 PXF47409.1 - 1.1e-40 139.1 0.0 1.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF47409.1 - 3.5e-13 48.9 0.1 6.3e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature tRNA-synt_His PF13393.6 PXF47410.1 - 6.2e-32 111.1 0.0 1e-31 110.4 0.0 1.3 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 PXF47410.1 - 1.4e-08 35.0 0.0 2.2e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PXF47410.1 - 8.6e-07 29.0 0.9 2.8e-06 27.4 0.4 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 PXF47410.1 - 0.011 14.8 0.0 0.13 11.3 0.0 2.4 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) SUI1 PF01253.22 PXF47411.1 - 1.5e-24 86.3 1.1 2e-24 85.9 1.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 PXF47411.1 - 0.054 13.8 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) F-box PF00646.33 PXF47412.1 - 0.0063 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF47412.1 - 0.024 14.5 2.0 0.45 10.4 0.2 2.5 2 0 0 2 2 2 0 F-box-like WD40 PF00400.32 PXF47413.1 - 6.5e-42 140.7 17.6 2.7e-07 31.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47413.1 - 1e-15 57.8 6.1 0.011 16.1 0.1 6.6 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF47413.1 - 1.3e-05 24.7 0.2 0.012 14.9 0.0 3.6 2 1 1 4 4 4 1 WD40-like domain Coatomer_WDAD PF04053.14 PXF47413.1 - 0.00014 21.1 0.7 1.4 7.8 0.0 3.3 2 1 0 3 3 3 2 Coatomer WD associated region Ge1_WD40 PF16529.5 PXF47413.1 - 0.0044 16.0 4.0 16 4.4 0.2 4.5 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CLTH PF10607.9 PXF47413.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Sec39 PF08314.11 PXF47413.1 - 0.028 12.9 0.1 0.037 12.5 0.1 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 IZUMO PF15005.6 PXF47413.1 - 0.067 13.7 0.4 0.18 12.3 0.4 1.7 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated 7tm_6 PF02949.20 PXF47413.1 - 0.078 12.0 0.3 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 7tm Odorant receptor B_lectin PF01453.24 PXF47413.1 - 0.085 13.4 1.5 0.33 11.5 0.2 2.5 2 0 0 2 2 2 0 D-mannose binding lectin Nup160 PF11715.8 PXF47413.1 - 0.14 10.8 2.0 5.2 5.6 0.0 3.4 2 2 2 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PXF47413.1 - 1.1 9.8 3.5 24 5.6 0.0 4.3 6 0 0 6 6 6 0 PQQ-like domain Gemin7 PF11095.8 PXF47414.1 - 3.4e-14 52.5 0.0 4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Methyltransf_21 PF05050.12 PXF47415.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain bZIP_2 PF07716.15 PXF47415.1 - 0.0082 16.2 4.6 0.0082 16.2 4.6 3.3 2 1 1 3 3 3 1 Basic region leucine zipper PAF-AH_p_II PF03403.13 PXF47416.1 - 1.5e-40 138.9 0.0 3.2e-40 137.8 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 PXF47416.1 - 4.1e-06 25.9 0.0 1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 PXF47416.1 - 2.2e-05 23.8 0.7 0.17 11.1 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF47416.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF47416.1 - 0.0013 19.4 1.8 0.0026 18.4 0.3 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 PXF47416.1 - 0.0088 15.1 0.1 3.6 6.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_5 PF12695.7 PXF47416.1 - 0.01 15.6 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DLH PF01738.18 PXF47416.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Pro_CA PF00484.19 PXF47416.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase Iso_dh PF00180.20 PXF47417.1 - 4.2e-65 220.2 0.0 4.8e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PseudoU_synth_2 PF00849.22 PXF47418.1 - 3.4e-10 40.3 0.0 7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase HTH_IclR PF09339.10 PXF47419.1 - 0.00012 21.8 0.1 0.00023 20.9 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_psq PF05225.16 PXF47419.1 - 0.00098 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 PXF47419.1 - 0.0014 18.4 0.2 0.0019 17.9 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain SpoIIID PF12116.8 PXF47419.1 - 0.0018 18.3 0.2 0.0024 17.9 0.2 1.2 1 0 0 1 1 1 1 Stage III sporulation protein D UPF0175 PF03683.13 PXF47419.1 - 0.047 13.4 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) TrmB PF01978.19 PXF47419.1 - 0.054 13.4 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.15 PXF47419.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 PXF47419.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ANT PF03374.14 PXF47419.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain DUF134 PF02001.16 PXF47419.1 - 0.16 12.5 0.1 0.23 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 Metallophos PF00149.28 PXF47420.1 - 2.4e-07 31.5 0.0 3.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF47420.1 - 6.7e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_transf_34 PF05637.12 PXF47421.1 - 6.7e-15 55.5 1.0 2.1e-08 34.2 0.1 3.1 2 1 1 3 3 3 3 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 PXF47421.1 - 0.00049 20.1 0.2 0.00077 19.5 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 PXF47421.1 - 0.0078 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 CLAMP PF14769.6 PXF47421.1 - 0.17 12.4 0.2 67 4.0 0.1 3.3 2 1 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DEAD PF00270.29 PXF47422.1 - 3.8e-43 147.3 0.0 5.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF47422.1 - 6e-22 78.1 0.0 1.3e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF47422.1 - 0.0064 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAD_porph PF04371.15 PXF47423.1 - 1.6e-87 293.8 0.0 1.9e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 PXF47423.1 - 0.0011 18.1 0.4 0.0057 15.8 0.1 2.0 2 0 0 2 2 2 1 Amidinotransferase Helicase_C PF00271.31 PXF47426.1 - 1.2e-15 57.8 0.1 1.4e-12 47.9 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 PXF47426.1 - 1e-10 41.6 0.0 7e-10 38.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 PXF47426.1 - 1.7e-06 28.7 4.6 4.7e-06 27.2 1.6 2.9 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 PXF47426.1 - 0.0012 18.9 0.0 0.008 16.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SlyX PF04102.12 PXF47426.1 - 0.19 12.3 1.6 0.62 10.7 1.6 1.8 1 0 0 1 1 1 0 SlyX SET PF00856.28 PXF47428.1 - 7.5e-08 32.9 0.0 2.5e-07 31.2 0.0 1.9 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 PXF47428.1 - 7.9e-06 26.6 0.5 1.8e-05 25.5 0.1 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Patched PF02460.18 PXF47429.1 - 3.8e-26 91.5 25.0 8.5e-16 57.2 0.2 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 PXF47429.1 - 3.8e-11 43.1 20.7 1.3e-10 41.3 5.0 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 PXF47429.1 - 3.6e-08 32.7 3.3 3.6e-08 32.7 3.3 2.3 2 0 0 2 2 2 1 MMPL family BRK PF07533.16 PXF47430.1 - 0.00021 20.8 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 BRK domain MFS_1 PF07690.16 PXF47431.1 - 2.1e-50 171.6 25.2 2.1e-50 171.6 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PXF47431.1 - 8.6e-06 24.3 7.9 0.00014 20.3 0.0 2.8 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF1269 PF06897.12 PXF47431.1 - 0.038 14.3 1.9 6.4 7.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) BT1 PF03092.16 PXF47431.1 - 0.62 8.2 18.3 0.42 8.8 6.7 2.3 1 1 0 2 2 2 0 BT1 family Glutaredoxin PF00462.24 PXF47432.1 - 6.2e-32 109.6 0.0 4e-15 55.8 0.0 3.0 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 PXF47432.1 - 2.3e-12 46.8 0.0 4.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PXF47432.1 - 5.2e-05 22.8 0.0 7.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PXF47432.1 - 0.00095 19.6 0.0 0.0042 17.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 PXF47432.1 - 0.0017 18.3 0.6 3.3 7.7 0.0 3.1 3 1 1 4 4 4 2 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.6 PXF47432.1 - 0.0029 18.0 0.0 4.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain RdRP PF05183.12 PXF47432.1 - 0.037 12.7 0.0 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA dependent RNA polymerase SH3BGR PF04908.15 PXF47432.1 - 0.066 13.4 0.8 1.8 8.8 0.0 3.0 3 0 0 3 3 3 0 SH3-binding, glutamic acid-rich protein Thioredoxin_8 PF13905.6 PXF47432.1 - 0.15 12.4 0.2 16 5.9 0.1 3.2 2 1 0 3 3 3 0 Thioredoxin-like Carb_anhydrase PF00194.21 PXF47433.1 - 5.2e-29 101.5 0.0 7.3e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 PXF47433.1 - 0.083 12.8 0.3 0.24 11.3 0.1 1.8 1 1 1 2 2 2 0 Putative carbonic anhydrase SSF PF00474.17 PXF47435.1 - 4.3e-17 62.1 26.7 8.4e-17 61.1 26.7 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Glycos_transf_2 PF00535.26 PXF47436.1 - 4.9e-10 39.5 0.1 1.5e-09 37.9 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF47436.1 - 1.4e-09 38.1 0.4 2.6e-09 37.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PXF47436.1 - 1.7e-06 27.6 0.1 5.9e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 PXF47436.1 - 1.5e-05 24.6 0.0 0.074 12.5 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 NodZ PF05830.11 PXF47436.1 - 0.00086 18.2 0.0 0.09 11.6 0.0 2.6 3 0 0 3 3 3 2 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PXF47436.1 - 0.0067 15.1 0.0 0.86 8.1 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase O-FucT PF10250.9 PXF47436.1 - 0.0074 16.0 0.1 0.023 14.4 0.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pkinase PF00069.25 PXF47438.1 - 1.4e-61 208.2 0.7 7.3e-61 205.8 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47438.1 - 6.8e-30 104.2 0.7 9.1e-22 77.6 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PXF47438.1 - 0.00013 21.3 0.0 0.0059 15.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PXF47438.1 - 0.00052 19.1 0.1 0.0009 18.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 PXF47438.1 - 0.0076 15.9 0.4 2.9 7.5 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PXF47438.1 - 0.01 14.7 0.0 0.021 13.6 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 PXF47438.1 - 0.021 13.9 0.2 0.033 13.2 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 PXF47438.1 - 0.022 14.7 4.9 0.047 13.6 0.4 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 PXF47438.1 - 0.041 13.5 0.2 0.1 12.2 0.2 1.6 1 1 0 1 1 1 0 RIO1 family CDP-OH_P_transf PF01066.21 PXF47439.1 - 2.8e-13 50.4 0.4 2.8e-13 50.4 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Frag1 PF10277.9 PXF47440.1 - 1.5e-13 50.9 10.0 1.8e-13 50.5 10.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Rieske PF00355.26 PXF47441.1 - 2e-15 56.5 0.0 5.1e-15 55.2 0.0 1.6 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PXF47441.1 - 7.6e-11 41.9 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain adh_short_C2 PF13561.6 PXF47442.1 - 4.4e-47 160.6 0.0 5e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PXF47442.1 - 4.8e-47 160.0 0.0 5.9e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PXF47442.1 - 4e-10 39.9 0.0 5.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PXF47442.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PXF47442.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PXF47442.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 PXF47442.1 - 0.003 17.0 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 PXF47442.1 - 0.0034 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 PXF47442.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PXF47442.1 - 0.11 12.7 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 PXF47442.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DnaJ_CXXCXGXG PF00684.19 PXF47443.1 - 0.076 13.4 18.2 1.1 9.6 10.8 2.9 1 1 1 2 2 2 0 DnaJ central domain DUF5351 PF17302.2 PXF47443.1 - 0.52 10.5 18.6 47 4.3 5.8 4.3 2 2 0 2 2 2 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 PXF47443.1 - 1.2 9.1 13.3 2.8 8.0 8.2 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1840 PF08895.11 PXF47444.1 - 0.36 11.2 0.0 0.36 11.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Pkinase PF00069.25 PXF47445.1 - 1.2e-54 185.5 0.0 1.8e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47445.1 - 1.1e-31 110.0 0.0 1.5e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF47445.1 - 5.4e-05 22.6 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF47445.1 - 0.00012 21.0 0.1 0.0014 17.5 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 PXF47445.1 - 0.0016 17.8 0.1 0.0085 15.4 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF47445.1 - 0.0023 17.9 0.2 0.0092 15.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Radical_SAM_N PF08497.10 PXF47445.1 - 0.16 11.2 0.1 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 Radical SAM N-terminal Peptidase_M24 PF00557.24 PXF47446.1 - 9.6e-53 179.0 0.2 1.2e-52 178.7 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 PXF47446.1 - 2.1e-18 66.3 6.3 4.3e-18 65.3 6.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PXF47446.1 - 5e-05 23.3 6.2 0.00013 21.9 6.2 1.8 1 0 0 1 1 1 1 MYND finger Sun2_CC2 PF18580.1 PXF47446.1 - 0.0058 16.8 0.5 0.012 15.8 0.5 1.5 1 0 0 1 1 1 1 SUN2 coiled coil domain 2 ATP-cone PF03477.16 PXF47446.1 - 0.058 14.0 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP cone domain RRM_1 PF00076.22 PXF47447.1 - 4e-22 77.8 0.0 1.7e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PXF47447.1 - 5.4e-10 40.2 2.8 8.6e-08 33.2 2.8 2.7 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 PXF47447.1 - 0.00026 20.9 0.3 0.015 15.3 0.2 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PXF47447.1 - 0.0015 18.4 0.0 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif bPH_2 PF03703.14 PXF47447.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain RRM_7 PF16367.5 PXF47447.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DSPc PF00782.20 PXF47448.1 - 2.8e-22 79.0 0.0 3.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PXF47448.1 - 0.00026 20.7 0.2 0.0004 20.0 0.2 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PXF47448.1 - 0.002 18.2 0.1 0.003 17.6 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family FAM76 PF16046.5 PXF47449.1 - 0.014 14.8 7.1 0.18 11.1 0.1 2.1 2 0 0 2 2 2 0 FAM76 protein DUF4201 PF13870.6 PXF47449.1 - 0.02 14.6 0.7 0.02 14.6 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Ku_PK_bind PF08785.11 PXF47449.1 - 0.095 12.9 0.1 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 Ku C terminal domain like PKcGMP_CC PF16808.5 PXF47449.1 - 0.15 11.9 0.9 0.39 10.6 0.9 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 PXF47449.1 - 1 8.6 9.0 4.3 6.6 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 PXF47449.1 - 1.8 9.3 4.1 26 5.5 0.2 2.7 2 0 0 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 PXF47449.1 - 2.9 8.0 9.7 0.29 11.2 1.8 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation O-FucT PF10250.9 PXF47450.1 - 2.4e-09 37.3 0.1 4.1e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Thioredoxin PF00085.20 PXF47451.1 - 4.9e-15 55.4 0.0 1.5e-11 44.2 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 PXF47451.1 - 2.6e-13 50.0 0.4 1.6e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PXF47451.1 - 3.4e-06 27.5 0.0 0.00071 20.0 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 PXF47451.1 - 0.0011 18.9 0.7 0.51 10.3 0.0 3.6 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 PXF47451.1 - 0.0014 18.8 0.0 0.006 16.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PXF47451.1 - 0.0092 16.3 0.1 0.14 12.5 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF47451.1 - 0.012 15.6 0.2 0.3 11.0 0.0 2.9 4 0 0 4 4 4 0 AhpC/TSA family AARP2CN PF08142.12 PXF47451.1 - 0.013 15.6 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 AARP2CN (NUC121) domain ZnuA PF01297.17 PXF47451.1 - 0.09 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Peripla_BP_6 PF13458.6 PXF47451.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein TraF PF13728.6 PXF47451.1 - 0.12 12.2 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein SHOCT PF09851.9 PXF47451.1 - 0.34 10.7 0.7 0.64 9.8 0.7 1.4 1 0 0 1 1 1 0 Short C-terminal domain Cytochrom_C1 PF02167.15 PXF47452.1 - 1.1e-94 316.3 0.0 1.2e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 PXF47452.1 - 0.00012 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PXF47452.1 - 0.011 16.9 0.1 0.034 15.3 0.1 2.1 1 1 0 1 1 1 0 Cytochrome c FapA PF03961.13 PXF47453.1 - 0.02 13.5 1.2 0.024 13.3 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_S PF02609.16 PXF47453.1 - 0.18 11.9 2.6 7.1 6.8 1.1 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit WD40 PF00400.32 PXF47454.1 - 3.9e-07 30.7 1.3 1.1 10.2 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Ldh_1_C PF02866.18 PXF47455.1 - 2.5e-33 115.4 0.0 4.1e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PXF47455.1 - 9.2e-32 110.1 0.1 1.9e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DnaJ PF00226.31 PXF47456.1 - 1.3e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 PXF47456.1 - 1.4e-06 28.4 0.0 1.7e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Pam16 Aminotran_5 PF00266.19 PXF47457.1 - 6e-90 301.9 0.0 7.7e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PXF47457.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PXF47457.1 - 0.0006 19.2 0.1 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PXF47457.1 - 0.001 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 PXF47457.1 - 0.03 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain MoCF_biosynth PF00994.24 PXF47458.1 - 1.3e-34 118.9 0.0 1.5e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain C2 PF00168.30 PXF47460.1 - 5.1e-05 23.5 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain FliMN_C PF01052.20 PXF47460.1 - 0.0015 18.5 0.0 0.0054 16.7 0.0 1.9 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term MscS_TM PF12794.7 PXF47462.1 - 0.12 11.2 0.2 0.18 10.6 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Rieske PF00355.26 PXF47463.1 - 8e-20 70.6 0.0 1.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PXF47463.1 - 5.3e-06 26.5 0.0 1.6e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF983 PF06170.12 PXF47463.1 - 0.026 14.9 3.4 0.053 13.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF983) UPF0220 PF05255.11 PXF47463.1 - 0.042 13.4 2.5 0.077 12.5 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) HtrL_YibB PF09612.10 PXF47465.1 - 1.2e-07 31.5 2.9 2.6e-07 30.5 2.9 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Glycos_transf_2 PF00535.26 PXF47465.1 - 0.0019 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 HtrL_YibB PF09612.10 PXF47466.1 - 8.6e-10 38.6 1.6 1.4e-09 37.8 1.6 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DUF4524 PF15025.6 PXF47466.1 - 0.11 12.3 0.1 0.89 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) ABC_membrane PF00664.23 PXF47467.1 - 5.1e-117 390.4 29.7 4.3e-63 213.5 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF47467.1 - 1.7e-71 239.1 0.0 9.3e-36 123.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PXF47467.1 - 5.2e-13 49.0 0.3 0.00023 20.7 0.3 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PXF47467.1 - 1.4e-08 35.4 0.4 0.0056 17.1 0.1 3.4 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 PXF47467.1 - 2e-07 31.4 1.9 0.073 13.3 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PXF47467.1 - 1.7e-06 28.0 0.1 0.069 13.1 0.0 4.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 PXF47467.1 - 2.4e-05 24.3 0.0 0.042 13.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PXF47467.1 - 3e-05 23.7 0.8 0.086 12.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PXF47467.1 - 3.8e-05 23.1 0.0 0.27 10.5 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 PXF47467.1 - 3.8e-05 22.7 1.4 0.13 11.1 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 PXF47467.1 - 7e-05 23.3 0.5 8.5 6.8 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PXF47467.1 - 0.0001 22.3 0.1 0.097 12.6 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_25 PF13481.6 PXF47467.1 - 0.00019 21.1 0.3 0.36 10.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PXF47467.1 - 0.00021 21.1 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 PXF47467.1 - 0.00044 19.5 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 PXF47467.1 - 0.00083 19.6 0.4 3.2 8.0 0.0 3.1 2 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 PXF47467.1 - 0.0013 18.6 1.2 2 8.1 0.0 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 PXF47467.1 - 0.0016 18.2 0.0 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 PXF47467.1 - 0.0024 18.1 2.2 4.2 7.7 0.3 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 PXF47467.1 - 0.0026 17.5 11.6 1.5 8.5 5.5 4.3 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PXF47467.1 - 0.004 17.7 0.0 2 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PXF47467.1 - 0.024 14.8 0.0 9.6 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PXF47467.1 - 0.026 13.7 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PXF47467.1 - 0.031 14.7 0.0 17 5.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 PXF47467.1 - 0.055 13.1 0.2 2 8.0 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 PXF47467.1 - 0.072 12.6 0.1 6.7 6.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 PXF47467.1 - 0.1 12.7 4.4 4.4 7.3 0.1 3.1 3 1 0 3 3 2 0 Helicase HerA, central domain APS_kinase PF01583.20 PXF47467.1 - 0.11 12.3 0.2 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 PXF47467.1 - 0.16 11.7 0.1 27 4.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain Lectin_C PF00059.21 PXF47469.1 - 3.3e-11 43.9 0.3 3.3e-11 43.9 0.3 2.4 3 0 0 3 3 3 1 Lectin C-type domain VWA_3 PF13768.6 PXF47469.1 - 6.1e-07 29.5 0.1 1.2e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain dCache_1 PF02743.18 PXF47469.1 - 0.00022 21.1 0.1 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 Cache domain VWA_2 PF13519.6 PXF47469.1 - 0.0003 21.4 0.1 0.00084 20.0 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PXF47469.1 - 0.0049 17.1 0.1 0.0099 16.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain SKG6 PF08693.10 PXF47469.1 - 0.027 13.9 0.8 0.056 12.9 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 PXF47469.1 - 0.037 13.9 0.3 0.078 12.9 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 PXF47469.1 - 0.13 13.2 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SapA PF02199.15 PXF47469.1 - 0.16 12.3 3.2 1 9.7 0.3 2.7 2 0 0 2 2 2 0 Saposin A-type domain PCI PF01399.27 PXF47470.1 - 4.3e-13 49.7 0.1 9e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 PXF47470.1 - 0.00043 19.9 0.1 0.0011 18.6 0.1 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Rubredoxin PF00301.20 PXF47471.1 - 0.0078 16.2 6.2 0.08 13.0 6.2 2.3 1 1 0 1 1 1 1 Rubredoxin Dor1 PF04124.12 PXF47472.1 - 2.7e-69 233.5 0.1 3.3e-69 233.1 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family FA_desaturase PF00487.24 PXF47473.1 - 2.2e-41 142.4 18.4 2.9e-41 142.0 18.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 PXF47473.1 - 7.8e-21 74.0 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Baculo_VP1054 PF05789.11 PXF47474.1 - 0.038 13.2 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus VP1054 protein zf-C2H2_jaz PF12171.8 PXF47475.1 - 0.00037 20.7 3.2 0.14 12.5 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PXF47475.1 - 0.0021 18.8 6.9 0.44 11.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zinc_ribbon_12 PF11331.8 PXF47475.1 - 0.0088 15.8 0.9 0.018 14.9 0.9 1.4 1 0 0 1 1 1 1 Probable zinc-ribbon domain CpXC PF14353.6 PXF47475.1 - 0.099 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 CpXC protein zf-C2H2 PF00096.26 PXF47475.1 - 0.53 10.9 5.8 1 9.9 1.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PXF47475.1 - 1.9 8.6 6.1 6.7 6.8 0.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 PXF47475.1 - 1.9 6.9 3.8 2.2 6.7 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) UPF0016 PF01169.19 PXF47477.1 - 7.7e-42 141.5 20.9 5.8e-21 74.6 5.9 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 OFeT_1 PF16955.5 PXF47477.1 - 0.045 13.4 0.3 0.087 12.5 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter DUF4131 PF13567.6 PXF47477.1 - 0.36 10.5 0.1 0.36 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SE PF08491.10 PXF47478.1 - 1.1e-94 316.5 0.0 1.4e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 PXF47478.1 - 5.2e-12 45.7 0.0 7.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PXF47478.1 - 7.1e-05 22.5 0.2 0.091 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PXF47478.1 - 0.0014 17.6 0.3 0.0023 16.8 0.0 1.4 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 PXF47478.1 - 0.011 16.0 0.2 0.042 14.1 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PXF47478.1 - 0.014 14.6 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF47478.1 - 0.098 11.7 1.4 2.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_5 PF05631.14 PXF47480.1 - 1.3e-112 376.2 12.9 1.6e-112 376.0 12.2 1.5 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 PXF47480.1 - 2.2e-16 59.8 33.8 2.6e-16 59.5 28.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily U3_assoc_6 PF08640.11 PXF47481.1 - 5.6e-16 58.4 2.0 1.7e-15 56.8 1.2 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 PXF47481.1 - 2.4e-05 24.8 4.6 0.087 13.7 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat APG6_N PF17675.1 PXF47482.1 - 2.7 8.5 17.8 8.8 6.9 0.2 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 PXF47482.1 - 3.1 8.0 16.6 1.4 9.1 5.3 3.6 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 AAA_23 PF13476.6 PXF47483.1 - 1.3e-09 38.9 0.0 1.3e-09 38.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain Metallophos PF00149.28 PXF47483.1 - 5.4e-07 30.3 0.0 1.1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SbcCD_C PF13558.6 PXF47483.1 - 3.9e-06 27.0 0.1 1.8e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Metallophos_2 PF12850.7 PXF47483.1 - 6.2e-06 26.5 0.0 3.4e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.19 PXF47483.1 - 4.6e-05 23.0 1.8 8.6e-05 22.1 1.8 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 PXF47483.1 - 3 8.4 9.3 1.8 9.0 1.1 3.9 4 1 0 4 4 4 0 ABC transporter Baculo_p24 PF05073.12 PXF47483.1 - 3.9 7.2 6.8 2.8 7.7 1.3 2.4 2 0 0 2 2 2 0 Baculovirus P24 capsid protein SNARE PF05739.19 PXF47484.1 - 2.3e-09 37.1 0.7 6e-09 35.8 0.7 1.8 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.21 PXF47484.1 - 0.024 14.5 0.2 0.038 13.8 0.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2987 PF11205.8 PXF47484.1 - 0.043 13.7 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) LXG PF04740.12 PXF47484.1 - 0.13 12.0 2.2 2 8.1 2.2 2.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily Myb_DNA-binding PF00249.31 PXF47488.1 - 3.1e-08 33.7 0.1 7.1e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF47488.1 - 0.0021 17.9 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like YabA PF06156.13 PXF47488.1 - 0.018 15.7 1.4 0.042 14.5 1.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Myb_DNA-bind_6 PF13921.6 PXF47488.1 - 0.24 11.7 1.6 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain CI-B14_5a PF07347.12 PXF47489.1 - 9.4e-06 25.4 1.5 1.5e-05 24.8 1.3 1.5 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) VCBS PF13517.6 PXF47490.1 - 4.7e-25 88.0 41.0 6e-11 42.8 6.5 6.7 3 2 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF47490.1 - 1.3e-06 28.4 29.3 0.015 15.4 0.2 6.0 6 0 0 6 6 6 5 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF47490.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 ASPIC and UnbV SET PF00856.28 PXF47491.1 - 9.4e-11 42.4 5.3 1.3e-09 38.7 0.0 3.5 2 2 0 2 2 2 1 SET domain preSET_CXC PF18264.1 PXF47491.1 - 8e-07 29.4 16.4 8e-07 29.4 16.4 2.7 2 0 0 2 2 2 1 CXC domain Phage_integrase PF00589.22 PXF47492.1 - 0.037 13.8 0.4 0.26 11.1 0.0 2.6 2 1 0 2 2 2 0 Phage integrase family TPT PF03151.16 PXF47493.1 - 4.2e-09 36.2 19.0 6.1e-09 35.6 19.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF47493.1 - 1.6e-05 25.1 38.6 0.0062 16.7 13.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family MCM PF00493.23 PXF47495.1 - 4e-83 277.9 0.0 6.5e-83 277.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PXF47495.1 - 7.4e-28 96.9 0.5 1.3e-27 96.1 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PXF47495.1 - 5.3e-27 94.1 3.8 1.1e-26 93.0 3.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PXF47495.1 - 1.2e-07 31.3 0.0 3.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PXF47495.1 - 1.3e-07 31.7 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PXF47495.1 - 8.3e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PXF47495.1 - 0.00023 21.6 0.0 0.0007 20.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF47495.1 - 0.073 13.4 1.9 0.5 10.7 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 PXF47495.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 PXF47495.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PXF47495.1 - 0.26 11.6 0.7 2.2 8.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain Tcp11 PF05794.13 PXF47496.1 - 1.1e-23 84.0 10.3 1.1e-23 84.0 10.3 2.9 3 1 0 3 3 3 1 T-complex protein 11 tRNA-synt_2b PF00587.25 PXF47498.1 - 1.6e-32 112.9 0.0 8.3e-30 104.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PXF47498.1 - 8.2e-18 64.3 0.8 1.8e-17 63.2 0.8 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 PXF47498.1 - 4.8e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 PXF47498.1 - 1.5e-06 28.2 0.0 5.6e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP_assoc PF03828.19 PXF47499.1 - 4.1e-11 42.9 0.3 1.2e-10 41.5 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PXF47499.1 - 9.2e-08 32.3 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PXF47499.1 - 0.00019 21.4 0.0 0.00067 19.7 0.0 1.8 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase AKAP95 PF04988.12 PXF47499.1 - 0.0045 17.2 0.1 0.01 16.1 0.1 1.5 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) ALS2CR11 PF15729.5 PXF47499.1 - 0.071 12.3 0.0 0.2 10.7 0.1 1.6 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 Lysine_decarbox PF03641.14 PXF47500.1 - 1.3e-25 90.0 0.0 1.7e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 PXF47500.1 - 1.8e-13 50.3 0.1 2.6e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family bZIP_1 PF00170.21 PXF47501.1 - 3.4e-07 30.3 8.8 3.4e-07 30.3 8.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF47501.1 - 0.0022 18.0 14.6 0.0022 18.0 14.6 2.7 2 1 0 2 2 2 1 Basic region leucine zipper DUF4509 PF14970.6 PXF47501.1 - 0.042 13.8 0.7 0.065 13.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) TINF2_N PF14973.6 PXF47501.1 - 0.044 14.1 0.2 0.07 13.5 0.2 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus ZapB PF06005.12 PXF47501.1 - 0.048 14.1 6.9 0.1 13.1 6.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF3450 PF11932.8 PXF47501.1 - 0.2 10.9 2.9 0.3 10.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Chibby PF14645.6 PXF47501.1 - 0.58 10.6 4.8 1.8 9.0 4.8 2.0 1 1 0 1 1 1 0 Chibby family DivIC PF04977.15 PXF47501.1 - 1.2 9.0 3.8 2.3 8.1 3.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Cnn_1N PF07989.11 PXF47501.1 - 8.9 6.5 8.7 4.9 7.4 5.4 2.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_Maf PF03131.17 PXF47501.1 - 9.1 6.9 15.1 0.63 10.6 5.7 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor YGGT PF02325.17 PXF47502.1 - 7.5e-17 61.5 5.1 1.4e-16 60.7 5.1 1.4 1 0 0 1 1 1 1 YGGT family HemY_N PF07219.13 PXF47505.1 - 0.024 14.8 0.1 0.077 13.2 0.1 1.8 1 0 0 1 1 1 0 HemY protein N-terminus RRS1 PF04939.12 PXF47506.1 - 4.4e-45 153.5 1.1 7.1e-45 152.8 1.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Myb_DNA-binding PF00249.31 PXF47507.1 - 2.1e-26 91.9 2.7 4e-13 49.3 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF47507.1 - 7.2e-23 80.6 2.6 6.2e-14 52.0 0.9 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 PXF47507.1 - 0.0054 16.8 3.3 0.84 9.8 0.1 3.1 3 1 1 4 4 4 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain PulG PF11773.8 PXF47507.1 - 1.3 8.9 3.8 0.46 10.4 0.2 2.1 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin Myb_Cef PF11831.8 PXF47508.1 - 2.5e-09 37.0 4.8 2.5e-09 37.0 4.8 2.5 1 1 1 2 2 2 1 pre-mRNA splicing factor component DHBP_synthase PF00926.19 PXF47509.1 - 2.7e-84 281.5 0.0 3.6e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 PXF47509.1 - 4.3e-57 192.2 0.0 1e-56 191.0 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II Kelch_5 PF13854.6 PXF47510.1 - 1.6e-26 91.8 0.3 3.6e-06 26.8 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PXF47510.1 - 3.2e-21 75.1 4.5 0.00033 20.6 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF47510.1 - 1.4e-19 69.9 8.4 1.3e-05 25.3 0.0 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF47510.1 - 5.8e-12 45.5 3.7 0.2 12.0 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 PXF47510.1 - 3.9e-06 26.6 1.8 0.58 10.2 0.0 5.1 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 PXF47510.1 - 0.22 11.1 4.2 38 4.0 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Cupin_5 PF06172.11 PXF47511.1 - 6e-37 127.0 0.0 6.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Acetyltransf_19 PF18015.1 PXF47511.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RTC PF01137.21 PXF47512.1 - 1.5e-57 194.3 0.2 2.1e-57 193.9 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PXF47512.1 - 1.4e-08 35.1 0.5 2.2e-06 28.1 0.2 2.4 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase_Tyr PF07714.17 PXF47513.1 - 3.9e-80 268.9 0.0 2.1e-68 230.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PXF47513.1 - 1.3e-67 228.0 0.0 4.9e-56 190.0 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PXF47513.1 - 2.4e-05 23.8 0.0 0.084 12.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PXF47513.1 - 8.2e-05 21.6 0.0 8.2e-05 21.6 0.0 3.0 3 1 0 3 3 3 1 Fungal protein kinase ANTH PF07651.16 PXF47513.1 - 0.00018 20.6 0.0 0.00041 19.4 0.0 1.6 1 0 0 1 1 1 1 ANTH domain APH PF01636.23 PXF47513.1 - 0.00035 20.6 0.2 0.31 10.9 0.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Siva PF05458.12 PXF47514.1 - 2.7e-07 30.5 17.7 2.7e-07 30.5 17.7 1.5 2 0 0 2 2 2 1 Cd27 binding protein (Siva) zf-B_box PF00643.24 PXF47514.1 - 6.5 7.0 18.6 0.23 11.6 4.4 2.8 2 1 1 3 3 3 0 B-box zinc finger PhoD PF09423.10 PXF47515.1 - 3.8e-16 59.1 3.9 1.2e-14 54.1 3.9 2.8 1 1 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.21 PXF47515.1 - 0.0051 17.1 0.2 0.055 13.8 0.2 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PXF47515.1 - 0.078 13.6 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain AMP-binding PF00501.28 PXF47516.1 - 1.1e-09 37.5 0.1 1.8e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme LRR_6 PF13516.6 PXF47517.1 - 2.1e-06 27.3 0.8 0.08 13.0 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 PXF47517.1 - 3.1e-05 24.2 0.2 0.046 14.2 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) DegT_DnrJ_EryC1 PF01041.17 PXF47518.1 - 2.8e-93 313.1 0.1 3.2e-93 312.9 0.1 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 PXF47518.1 - 0.00016 20.9 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II COX2 PF00116.20 PXF47518.1 - 0.014 15.3 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain GARS_A PF01071.19 PXF47519.1 - 3.4e-79 265.2 0.0 4.6e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 PXF47519.1 - 1.5e-28 99.4 0.0 2.9e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 PXF47519.1 - 8.9e-28 96.4 1.3 1.9e-27 95.3 0.4 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain RimK PF08443.11 PXF47519.1 - 6e-05 22.7 0.1 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 PXF47519.1 - 0.00041 20.4 0.0 0.00076 19.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PXF47519.1 - 0.0016 18.0 0.0 0.0033 16.9 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 PXF47519.1 - 0.002 17.8 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 PXF47519.1 - 0.003 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Asp PF00026.23 PXF47520.1 - 1.1e-40 140.0 0.0 2.4e-40 138.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 PXF47520.1 - 4.8e-12 45.9 0.0 1.8e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PXF47520.1 - 9.2e-11 42.3 3.7 2e-10 41.2 3.7 1.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 PXF47520.1 - 0.0079 16.7 0.2 9.8 6.8 0.0 3.8 3 1 1 4 4 4 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PXF47520.1 - 0.0081 16.8 2.7 3.5 8.3 0.1 3.5 3 1 0 3 3 3 2 Aspartyl protease Pex16 PF08610.10 PXF47521.1 - 2.1e-31 109.3 1.3 3.5e-31 108.6 1.3 1.3 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RRM_1 PF00076.22 PXF47522.1 - 1.7e-11 43.8 0.0 2.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF47522.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIS_C PF01096.18 PXF47523.1 - 1.2e-20 73.0 10.8 2e-20 72.3 4.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 PXF47523.1 - 1.1e-05 25.2 1.9 1.1e-05 25.2 1.9 2.6 2 1 0 2 2 1 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 PXF47523.1 - 0.027 14.0 2.5 4.4 6.9 0.2 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding PH_17 PF18012.1 PXF47523.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 PH domain zf-ribbon_3 PF13248.6 PXF47523.1 - 0.093 12.2 4.6 0.89 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 PXF47523.1 - 0.14 12.3 5.2 4.5 7.5 0.1 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 PXF47523.1 - 0.14 12.1 6.2 1.4 8.9 2.6 3.2 2 1 0 2 2 2 0 Nudix N-terminal zf-FPG_IleRS PF06827.14 PXF47523.1 - 0.21 11.5 9.7 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.6 PXF47523.1 - 0.22 11.9 4.4 6.9 7.1 1.3 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 PXF47523.1 - 0.66 9.8 7.1 1.8 8.4 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.12 PXF47523.1 - 1.1 9.3 10.9 7.8 6.6 7.5 2.9 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF3797 PF12677.7 PXF47523.1 - 1.4 8.9 5.5 0.47 10.4 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Zn_Tnp_IS1595 PF12760.7 PXF47523.1 - 1.8 8.6 11.2 0.19 11.7 1.0 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DNA_repr_REX1B PF14966.6 PXF47525.1 - 3.8e-09 37.1 1.0 3.9e-05 24.2 0.5 3.9 2 1 0 2 2 2 1 DNA repair REX1-B DUF4588 PF15251.6 PXF47525.1 - 0.072 12.8 0.8 0.1 12.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Baculo_PEP_C PF04513.12 PXF47525.1 - 0.096 12.7 0.2 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEMT PF04191.13 PXF47526.1 - 1.1e-26 93.3 3.3 1.1e-26 93.3 3.3 1.8 3 0 0 3 3 3 1 Phospholipid methyltransferase Cyclin_N PF00134.23 PXF47527.1 - 4.6e-18 65.2 0.0 1.1e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 PXF47527.1 - 0.00056 20.0 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 PXF47527.1 - 0.0035 17.4 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Acyltransferase PF01553.21 PXF47528.1 - 1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PPI_Ypi1 PF07491.11 PXF47529.1 - 1.9e-16 59.7 15.4 1.7e-15 56.6 15.4 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor DTHCT PF08070.11 PXF47529.1 - 0.16 12.7 4.7 0.056 14.2 2.3 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region PseudoU_synth_1 PF01416.20 PXF47530.1 - 5.5e-28 97.6 0.0 4.7e-27 94.6 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase Hydrolase_4 PF12146.8 PXF47533.1 - 1.2e-12 47.7 0.0 4e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF47533.1 - 5.1e-12 46.9 0.0 6.2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF47533.1 - 3.7e-10 39.9 0.0 6.1e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 PXF47533.1 - 2.6e-05 24.1 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Thioesterase PF00975.20 PXF47533.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain His_Phos_2 PF00328.22 PXF47535.1 - 1.2e-24 87.4 0.0 1.9e-24 86.7 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyoxalase PF00903.25 PXF47536.1 - 3.6e-06 27.2 0.0 5.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 PXF47536.1 - 0.00043 20.2 0.0 0.00065 19.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 PXF47536.1 - 0.0025 18.6 0.0 0.0038 18.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain RNA_pol_Rpb2_3 PF04565.16 PXF47536.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 TruB_C PF09142.11 PXF47536.1 - 0.073 12.9 0.4 0.21 11.4 0.1 1.9 1 1 1 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Rhomboid PF01694.22 PXF47537.1 - 2.5e-24 86.0 8.3 3.9e-24 85.4 8.3 1.3 1 0 0 1 1 1 1 Rhomboid family Ribosomal_L4 PF00573.22 PXF47539.1 - 4.8e-57 192.7 0.1 5.9e-57 192.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Voltage_CLC PF00654.20 PXF47540.1 - 1.2e-86 291.2 28.6 1.2e-86 291.2 28.6 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PXF47540.1 - 0.00015 22.2 0.0 0.056 13.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF3169 PF11368.8 PXF47540.1 - 0.82 9.1 3.8 2.8 7.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) TatD_DNase PF01026.21 PXF47542.1 - 9.3e-56 189.0 0.1 1e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 PXF47542.1 - 0.024 14.4 0.1 0.54 10.0 0.0 2.6 2 1 0 2 2 2 0 Amidohydrolase PK_C PF02887.16 PXF47542.1 - 0.067 13.4 0.0 0.44 10.8 0.0 2.2 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain DAGK_cat PF00781.24 PXF47543.1 - 2.5e-20 72.3 0.1 4.1e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_A4 PF01828.17 PXF47543.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase A4 family Patatin PF01734.22 PXF47544.1 - 4.9e-24 85.6 0.0 1.1e-23 84.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 PXF47544.1 - 1e-22 80.3 1.9 1.2e-20 73.7 0.1 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3336) Solute_trans_a PF03619.16 PXF47546.1 - 9.5e-80 267.9 12.5 1.1e-79 267.7 12.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 PXF47546.1 - 3.2 8.0 12.4 1.1 9.5 3.9 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) zinc_ribbon_6 PF14599.6 PXF47547.1 - 1.2e-20 73.3 0.7 1.2e-20 73.3 0.7 4.0 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 PXF47547.1 - 4.8e-17 62.2 24.1 4.8e-17 62.2 24.1 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 PXF47547.1 - 2.6e-09 37.2 5.0 2.6e-09 37.2 5.0 5.1 3 1 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 PXF47547.1 - 1e-08 35.0 4.9 1e-08 35.0 4.9 5.6 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF47547.1 - 3e-08 33.6 1.1 3e-08 33.6 1.1 4.0 5 1 1 6 6 6 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PXF47547.1 - 3.4e-07 30.0 5.0 3.4e-07 30.0 5.0 4.9 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PXF47547.1 - 0.00016 21.7 5.2 0.00016 21.7 5.2 4.9 4 1 2 6 6 6 1 zinc finger of C3HC4-type, RING Cytochrome_C7 PF14522.6 PXF47547.1 - 0.00053 19.9 6.4 0.00053 19.9 6.4 3.6 2 1 0 2 2 2 1 Cytochrome c7 and related cytochrome c zf-rbx1 PF12678.7 PXF47547.1 - 0.00059 20.1 6.0 0.00059 20.1 6.0 4.2 2 1 2 4 4 4 1 RING-H2 zinc finger domain Rtf2 PF04641.12 PXF47547.1 - 0.003 17.0 0.6 0.003 17.0 0.6 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger Uma2 PF05685.12 PXF47548.1 - 1.4e-25 89.9 0.0 1.7e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease UDPG_MGDP_dh_N PF03721.14 PXF47549.1 - 1.3e-61 207.5 0.1 2.4e-61 206.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PXF47549.1 - 3.7e-38 130.2 1.1 7.5e-36 122.7 0.3 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 PXF47549.1 - 1.1e-30 105.6 0.0 2.4e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 PXF47549.1 - 0.02 15.1 0.1 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 PXF47549.1 - 0.076 13.1 0.2 4.7 7.3 0.1 3.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase XPG_N PF00752.17 PXF47549.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain NAD_Gly3P_dh_N PF01210.23 PXF47549.1 - 0.13 12.2 0.1 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.23 PXF47549.1 - 0.14 12.2 0.0 2.2 8.3 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PCRF PF03462.18 PXF47550.1 - 1.3e-52 178.4 0.9 4.1e-52 176.9 0.1 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 PXF47550.1 - 8e-34 116.0 0.4 1.8e-33 114.9 0.4 1.6 1 0 0 1 1 1 1 RF-1 domain ANTAR PF03861.14 PXF47551.1 - 0.0034 17.2 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 ANTAR domain Spexin PF15171.6 PXF47551.1 - 0.12 12.6 1.1 0.27 11.4 1.1 1.7 1 1 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin tRNA-synt_2d PF01409.20 PXF47552.1 - 2.3e-54 184.5 0.0 3.4e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 PXF47552.1 - 7.2e-21 73.9 2.5 7.2e-21 73.9 2.5 1.7 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1542 PF07564.11 PXF47552.1 - 0.03 14.4 1.9 0.03 14.4 1.9 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) ATP-synt_I PF03899.15 PXF47553.1 - 0.031 14.6 0.6 0.044 14.2 0.6 1.2 1 0 0 1 1 1 0 ATP synthase I chain FancD2 PF14631.6 PXF47554.1 - 4.2e-98 329.4 37.4 2.4e-33 114.8 1.1 6.3 4 2 2 6 6 6 5 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 PXF47554.1 - 3.3e-07 30.7 0.6 4.3e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 FANCI solenoid 2 Radical_SAM_C PF16199.5 PXF47556.1 - 0.058 13.4 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Radical_SAM C-terminal domain SlyX PF04102.12 PXF47557.1 - 0.049 14.3 8.9 0.082 13.5 0.6 2.8 3 0 0 3 3 3 0 SlyX Atg14 PF10186.9 PXF47557.1 - 0.068 12.2 2.6 0.1 11.7 2.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1690 PF07956.11 PXF47557.1 - 0.28 11.6 5.4 0.78 10.2 1.1 2.5 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DLP_helical PF18709.1 PXF47557.1 - 0.6 9.3 4.3 0.25 10.5 0.8 1.8 1 1 0 2 2 2 0 Dynamin-like helical domain TMF_TATA_bd PF12325.8 PXF47557.1 - 0.8 9.9 11.9 0.22 11.8 0.7 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 PXF47557.1 - 4.6 7.1 9.4 2.5 7.9 0.1 2.8 3 0 0 3 3 3 0 Septum formation initiator SNARE_assoc PF09335.11 PXF47558.1 - 2.1e-18 66.9 9.9 3.8e-18 66.1 7.2 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1289 PF06945.13 PXF47559.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF1995 PF09353.10 PXF47560.1 - 4.3e-11 43.2 0.0 6.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) ERCC4 PF02732.15 PXF47561.1 - 1.6e-12 47.9 0.0 4.3e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_60s PF00428.19 PXF47562.1 - 3.2e-21 75.7 10.7 3.7e-21 75.5 10.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4366 PF14283.6 PXF47562.1 - 0.11 12.5 0.7 0.15 12.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ribosomal_L11_N PF03946.14 PXF47563.1 - 1e-19 70.1 0.5 2.1e-19 69.1 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PXF47563.1 - 4.7e-18 65.5 0.4 7e-18 64.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Fe_bilin_red PF05996.12 PXF47564.1 - 2.1e-76 256.6 0.0 2.6e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase DEAD PF00270.29 PXF47565.1 - 1.2e-49 168.5 0.0 2.7e-49 167.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF47565.1 - 4.5e-30 104.3 0.0 1.5e-29 102.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PXF47565.1 - 2.7e-05 23.5 0.1 4.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PXF47565.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF47565.1 - 0.014 15.7 0.1 0.086 13.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Nitroreductase PF00881.24 PXF47565.1 - 0.056 13.5 0.1 0.39 10.7 0.0 2.3 2 1 0 2 2 2 0 Nitroreductase family Med31 PF05669.12 PXF47566.1 - 3.3e-36 123.2 7.8 4.1e-36 122.9 7.8 1.1 1 0 0 1 1 1 1 SOH1 Fer2_4 PF13510.6 PXF47567.1 - 3.5e-19 68.6 0.4 6.5e-19 67.8 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PXF47567.1 - 4.2e-16 58.2 0.1 4.2e-16 58.2 0.1 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 PXF47567.1 - 3.1e-09 36.7 0.8 3.1e-09 36.7 0.8 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 PXF47567.1 - 0.035 13.9 1.6 1.5 8.7 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain AAA PF00004.29 PXF47568.1 - 2.2e-44 151.1 0.0 5.5e-44 149.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PXF47568.1 - 3.5e-05 23.6 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PXF47568.1 - 0.00012 22.5 0.4 0.0025 18.2 0.2 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PXF47568.1 - 0.00094 19.2 0.0 0.0045 17.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PXF47568.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF47568.1 - 0.002 18.4 0.6 0.089 13.1 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 PXF47568.1 - 0.0033 18.0 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PXF47568.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 PXF47568.1 - 0.014 15.4 0.1 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PXF47568.1 - 0.023 14.1 0.0 0.06 12.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PXF47568.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_lid_3 PF17862.1 PXF47568.1 - 0.051 13.4 0.0 0.87 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA+ lid domain Vps4_C PF09336.10 PXF47568.1 - 0.06 13.4 0.2 0.21 11.6 0.2 1.9 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 PXF47568.1 - 0.073 13.2 0.0 0.53 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 PXF47568.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PXF47568.1 - 0.098 12.2 0.0 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PXF47568.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PXF47568.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 PXF47568.1 - 0.13 11.4 0.0 0.48 9.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 PXF47568.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAR2 PF05282.11 PXF47569.1 - 6.3e-24 85.0 0.6 1.6e-21 77.2 0.1 2.1 1 1 1 2 2 2 2 AAR2 protein TGT PF01702.18 PXF47570.1 - 3e-91 306.2 0.0 6.6e-91 305.1 0.0 1.5 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase RE_LlaMI PF09562.10 PXF47570.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 LlaMI restriction endonuclease zf-RING_2 PF13639.6 PXF47571.1 - 2.9e-08 33.9 13.0 5.3e-08 33.1 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PXF47571.1 - 2.3e-06 27.4 12.7 4.9e-06 26.4 12.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF47571.1 - 0.00012 22.0 11.6 0.00027 20.9 11.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF47571.1 - 0.00039 20.2 14.0 0.00079 19.2 14.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF47571.1 - 0.00052 19.8 12.7 0.0011 18.8 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF47571.1 - 0.001 19.1 6.1 0.0051 16.8 6.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PXF47571.1 - 0.0016 18.7 11.4 0.018 15.4 11.8 2.3 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PXF47571.1 - 0.002 17.8 7.7 0.002 17.8 7.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PXF47571.1 - 0.0053 16.9 12.0 0.0097 16.0 12.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF3552 PF12072.8 PXF47571.1 - 0.0087 15.5 22.1 0.0087 15.5 22.1 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3552) zf-C3HC4_3 PF13920.6 PXF47571.1 - 0.018 14.9 13.0 0.05 13.5 13.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF47571.1 - 0.06 13.2 13.1 0.72 9.8 6.9 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SelR PF01641.18 PXF47571.1 - 0.085 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 SelR domain zf-RING-like PF08746.11 PXF47571.1 - 0.17 12.2 12.2 0.33 11.3 12.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-RRN7 PF11781.8 PXF47571.1 - 0.37 10.5 2.5 0.83 9.4 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_6 PF14835.6 PXF47571.1 - 0.69 9.8 5.4 1.4 8.8 5.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zf_RING PF16744.5 PXF47571.1 - 0.71 10.0 8.4 2.2 8.4 8.4 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 PXF47571.1 - 0.85 9.3 9.5 1.8 8.3 9.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 PXF47571.1 - 0.89 9.5 10.5 2.4 8.2 7.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 PXF47571.1 - 6.9 6.9 9.0 14 5.9 5.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain V_ATPase_I PF01496.19 PXF47571.1 - 7.7 4.3 9.5 13 3.5 9.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gp_dh_C PF02800.20 PXF47572.1 - 2.1e-62 209.4 0.4 1e-61 207.1 0.1 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PXF47572.1 - 2.9e-34 117.4 0.2 7.3e-34 116.1 0.2 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 PXF47572.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase VHL PF01847.16 PXF47573.1 - 1.6e-16 60.0 0.3 2.4e-16 59.4 0.3 1.2 1 0 0 1 1 1 1 VHL beta domain Arm PF00514.23 PXF47574.1 - 1.9e-08 34.0 1.7 0.00022 21.1 0.1 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 PXF47574.1 - 0.0015 18.3 4.4 0.0042 16.8 0.6 2.6 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis V-ATPase_H_N PF03224.14 PXF47574.1 - 0.011 15.1 9.6 0.022 14.1 3.6 2.5 1 1 0 2 2 2 0 V-ATPase subunit H CTD_bind PF04818.13 PXF47574.1 - 0.028 15.2 1.3 3.5 8.5 0.1 3.4 4 0 0 4 4 4 0 RNA polymerase II-binding domain. Atx10homo_assoc PF09759.9 PXF47574.1 - 0.38 10.8 3.2 11 6.1 0.2 3.7 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Hydrolase_4 PF12146.8 PXF47575.1 - 2.2e-09 36.9 0.0 1.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF47575.1 - 3.8e-06 27.7 0.0 6.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF47575.1 - 4e-05 23.4 0.0 0.00033 20.4 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 PXF47575.1 - 0.025 13.3 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 PXF47575.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PXF47575.1 - 0.037 13.6 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PXF47575.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 PXF47575.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sec1 PF00995.23 PXF47576.1 - 4.7e-121 405.8 0.0 5.8e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ETF_QO PF05187.13 PXF47577.1 - 7.9e-46 154.5 0.3 1.2e-45 153.8 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 PXF47577.1 - 7.4e-08 31.9 0.2 3.2e-05 23.2 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PXF47577.1 - 1.1e-07 31.9 0.0 7.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF47577.1 - 1.1e-07 31.8 0.4 4.2e-05 23.3 0.7 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 PXF47577.1 - 1.7e-07 30.8 0.0 3.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PXF47577.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PXF47577.1 - 5.5e-05 22.5 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PXF47577.1 - 0.00011 21.4 0.1 0.00016 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 PXF47577.1 - 0.00031 19.6 0.1 0.00049 18.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 PXF47577.1 - 0.00093 18.5 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF47577.1 - 0.0013 18.7 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 PXF47577.1 - 0.0035 17.9 0.1 4.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PXF47577.1 - 0.024 13.5 0.0 0.36 9.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 PXF47577.1 - 0.039 13.1 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 PXF47577.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_7 PF12838.7 PXF47577.1 - 0.048 14.3 0.9 0.12 13.0 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 PXF47577.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ATP_bind_3 PF01171.20 PXF47578.1 - 1.3e-35 122.8 0.0 2.1e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Thioredoxin PF00085.20 PXF47579.1 - 1.7e-19 69.7 0.0 2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF47579.1 - 7.7e-07 29.5 0.0 0.00012 22.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PXF47579.1 - 0.0027 17.8 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PXF47579.1 - 0.14 12.5 0.0 0.64 10.4 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like TraF PF13728.6 PXF47579.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein ThiF PF00899.21 PXF47580.1 - 2.4e-46 158.1 0.0 3.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 PXF47580.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PXF47580.1 - 0.009 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 PXF47580.1 - 0.15 11.7 0.1 0.38 10.4 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 PXF47580.1 - 4.4 6.4 5.6 0.46 9.7 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain Spec3 PF15795.5 PXF47581.1 - 1.9e-08 34.7 13.4 9e-06 26.1 13.4 2.1 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein SMN PF06003.12 PXF47581.1 - 0.82 8.9 5.9 1.1 8.5 5.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Sedlin_N PF04628.13 PXF47582.1 - 2.1e-37 128.2 0.0 2.3e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PXF47582.1 - 0.0023 17.9 0.1 0.0025 17.7 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Peptidase_C32 PF05411.12 PXF47582.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DEAD PF00270.29 PXF47583.1 - 3.4e-44 150.7 0.0 6.9e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF47583.1 - 1.7e-23 83.1 0.5 1.4e-22 80.1 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PXF47583.1 - 8.4e-16 57.9 0.1 3.1e-15 56.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PXF47583.1 - 2.9e-07 30.6 0.2 2.2e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TRAPPC9-Trs120 PF08626.11 PXF47584.1 - 1.4e-16 59.1 4.0 1.5e-08 32.6 0.4 3.6 2 2 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF4680 PF15730.5 PXF47584.1 - 7.4 6.9 7.8 0.16 12.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4680) Dak1 PF02733.17 PXF47585.1 - 1.5e-89 299.9 0.7 2.3e-89 299.4 0.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 PXF47585.1 - 1.2e-30 106.7 0.9 1.2e-30 106.7 0.9 1.6 2 0 0 2 2 2 1 DAK2 domain PITH PF06201.13 PXF47586.1 - 7.6e-37 126.9 0.0 9.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain NAD_kinase PF01513.21 PXF47587.1 - 4.1e-62 210.0 0.0 6.2e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase ADK PF00406.22 PXF47587.1 - 5e-29 101.3 0.0 1.1e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PXF47587.1 - 4.6e-15 56.3 0.0 1.8e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF47587.1 - 4.9e-05 23.9 0.1 0.0002 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 PXF47587.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 PXF47587.1 - 0.00043 20.4 3.1 0.0015 18.7 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PXF47587.1 - 0.0011 18.6 0.0 0.004 16.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 PXF47587.1 - 0.0044 17.4 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF47587.1 - 0.013 15.7 0.4 0.053 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PXF47587.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 PXF47587.1 - 0.022 15.2 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DAGK_cat PF00781.24 PXF47587.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DRIM PF07539.12 PXF47587.1 - 0.058 11.7 0.2 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 Down-regulated in metastasis AAA_5 PF07728.14 PXF47587.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 PXF47587.1 - 0.096 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PXF47587.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 PXF47587.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 PXF47587.1 - 0.18 12.3 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy PF03171.20 PXF47590.1 - 2.4e-11 44.0 0.0 4.1e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 PXF47592.1 - 3e-86 289.6 0.0 4.1e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF47592.1 - 3.4e-24 85.6 0.2 8.8e-24 84.3 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PXF47592.1 - 9.3e-12 44.7 0.1 2.2e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DNA_alkylation PF08713.11 PXF47593.1 - 4.2e-32 111.6 0.2 5.2e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme DUF1065 PF06358.11 PXF47593.1 - 0.13 12.2 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) ClpS PF02617.17 PXF47595.1 - 6.5e-15 54.7 0.0 1.3e-14 53.7 0.0 1.5 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS tRNA-synt_2b PF00587.25 PXF47596.1 - 5.8e-31 107.8 0.0 1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PXF47596.1 - 8.2e-17 61.4 5.0 1.5e-16 60.6 5.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 PXF47596.1 - 0.033 14.4 3.1 1.4 9.1 0.5 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Memo PF01875.17 PXF47597.1 - 4.3e-77 258.9 0.1 4.9e-77 258.7 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein Yippee-Mis18 PF03226.14 PXF47598.1 - 1.1e-15 57.7 1.0 1.3e-15 57.5 1.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 PXF47598.1 - 0.066 13.4 2.3 0.1 12.9 2.3 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I GATA PF00320.27 PXF47599.1 - 5.3e-10 38.7 4.4 1.4e-09 37.3 4.4 1.8 1 0 0 1 1 1 1 GATA zinc finger Med15 PF09606.10 PXF47599.1 - 0.0015 17.3 8.0 0.0018 17.1 8.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 PXF47599.1 - 0.0042 16.7 10.8 0.0058 16.3 10.8 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 PXF47599.1 - 0.0065 16.5 13.9 0.0078 16.3 13.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mit_KHE1 PF10173.9 PXF47599.1 - 0.084 13.0 1.1 0.11 12.6 0.4 1.5 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related PAT1 PF09770.9 PXF47599.1 - 2 6.6 12.3 2.3 6.4 12.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 PXF47599.1 - 6.1 7.9 7.2 0.72 10.8 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 PXF47599.1 - 9.4 6.2 10.7 0.9 9.6 4.9 1.9 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TraB PF01963.17 PXF47600.1 - 8.3e-13 48.8 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 TraB family WD40 PF00400.32 PXF47601.1 - 2.4e-13 50.3 2.6 0.0045 17.8 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47601.1 - 1.1e-05 25.7 0.0 0.00039 20.7 0.0 2.9 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain UPF0449 PF15136.6 PXF47601.1 - 0.051 14.0 0.5 0.12 12.9 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 TSC22 PF01166.18 PXF47601.1 - 0.14 12.5 1.1 0.25 11.7 1.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 PXF47602.1 - 0.24 11.5 21.4 1 9.5 21.4 2.1 1 1 0 1 1 1 0 bZIP transcription factor DUF4140 PF13600.6 PXF47602.1 - 3.2 8.2 8.6 1.2 9.6 5.2 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PAD_M PF08527.10 PXF47603.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain TSC22 PF01166.18 PXF47604.1 - 0.0013 19.0 0.6 0.0032 17.7 0.6 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_2 PF07716.15 PXF47604.1 - 0.011 15.8 16.0 0.011 15.8 16.0 2.2 1 1 2 3 3 3 0 Basic region leucine zipper VasL PF12486.8 PXF47604.1 - 0.062 13.2 4.5 0.12 12.2 4.5 1.4 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL DUF2576 PF10845.8 PXF47604.1 - 0.13 11.9 0.1 0.72 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) YabA PF06156.13 PXF47604.1 - 0.59 10.8 3.4 0.75 10.5 2.5 1.6 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 PXF47604.1 - 0.78 10.3 15.5 0.42 11.2 9.0 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor PRKG1_interact PF15898.5 PXF47604.1 - 3.6 8.6 12.2 6.7 7.7 12.2 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SPC22 PF04573.12 PXF47607.1 - 8.7e-45 152.3 0.1 9.7e-45 152.1 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit efThoc1 PF11957.8 PXF47608.1 - 9.6e-27 93.8 0.1 1.6e-14 53.5 0.1 2.4 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Rabaptin PF03528.15 PXF47608.1 - 0.17 10.6 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Rabaptin Zip PF02535.22 PXF47609.1 - 5.9e-32 111.2 30.1 5.8e-21 75.1 13.9 3.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4484 PF14831.6 PXF47609.1 - 0.057 13.5 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) efThoc1 PF11957.8 PXF47610.1 - 1.4e-25 90.0 0.4 8e-17 61.1 0.6 2.4 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor CRISPR_Cse2 PF09485.10 PXF47610.1 - 0.043 14.4 0.1 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TB2_DP1_HVA22 PF03134.19 PXF47611.1 - 7.1e-17 61.1 1.7 8.7e-17 60.8 1.7 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PPR_2 PF13041.6 PXF47612.1 - 1.1e-10 41.5 0.0 0.07 13.3 0.1 5.5 7 0 0 7 7 7 3 PPR repeat family PPR_3 PF13812.6 PXF47612.1 - 0.00023 21.2 0.1 0.76 9.9 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 PXF47612.1 - 0.00045 20.3 0.1 38 4.8 0.0 5.8 7 0 0 7 7 7 0 PPR repeat PPR_long PF17177.4 PXF47612.1 - 0.0057 16.1 0.4 0.87 8.9 0.0 3.4 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PXF47612.1 - 1.2 8.9 3.8 23 4.8 0.0 3.9 4 0 0 4 4 4 0 PPR repeat WD40 PF00400.32 PXF47613.1 - 1.2e-18 67.1 19.4 6.4e-05 23.6 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47613.1 - 2.1e-08 34.3 0.2 0.022 15.0 0.0 4.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF47613.1 - 0.00043 19.3 0.0 1.9 7.4 0.0 3.5 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PXF47613.1 - 0.005 16.7 0.4 1.2 9.1 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 PXF47613.1 - 0.078 11.0 0.2 5.9 4.7 0.2 3.0 3 0 0 3 3 3 0 IKI3 family GRDP-like PF07173.12 PXF47615.1 - 1.1e-33 116.9 2.1 6.2e-27 95.0 1.4 2.4 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like DUF3922 PF13059.6 PXF47615.1 - 0.072 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Nucleotid_trans PF03407.16 PXF47616.1 - 1.1e-16 61.5 0.0 1.9e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase GCV_T PF01571.21 PXF47617.1 - 2.2e-09 37.1 0.0 3.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain PCMT PF01135.19 PXF47618.1 - 3.9e-61 206.5 0.0 4.8e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PXF47618.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF47618.1 - 0.0055 17.4 0.0 0.0097 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF47618.1 - 0.0084 15.5 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PXF47618.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PXF47618.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 PXF47618.1 - 0.16 12.7 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 PXF47618.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Trp_Tyr_perm PF03222.13 PXF47620.1 - 9.1e-05 21.7 0.2 9.1e-05 21.7 0.2 2.7 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family KH_2 PF07650.17 PXF47621.1 - 1.7e-11 43.7 0.9 2.8e-11 43.1 0.9 1.3 1 0 0 1 1 1 1 KH domain GTP_EFTU PF00009.27 PXF47621.1 - 7.8e-09 35.4 0.1 1.1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PXF47621.1 - 2.3e-06 27.2 0.3 3.7e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 PXF47621.1 - 0.017 14.1 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 PXF47621.1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF948 PF06103.11 PXF47623.1 - 4.5 7.6 5.6 67 3.8 2.3 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 PXF47624.1 - 1.1e-53 182.4 0.0 1.3e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47624.1 - 3.7e-23 82.1 0.0 4.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF47624.1 - 4.5e-05 22.4 0.5 0.00015 20.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PXF47624.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 PXF47624.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2232 PF09991.9 PXF47625.1 - 1.5e-09 37.5 17.1 2.6e-09 36.7 17.1 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) DAO PF01266.24 PXF47626.1 - 1.8e-36 126.5 0.3 2.1e-36 126.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF47626.1 - 2.8e-05 23.4 0.2 8.6e-05 21.8 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PXF47626.1 - 3.6e-05 23.9 0.1 9.3e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 PXF47626.1 - 0.00054 19.6 0.0 0.00099 18.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 PXF47626.1 - 0.00066 20.1 0.0 0.0013 19.2 0.0 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 PXF47626.1 - 0.00067 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF47626.1 - 0.00076 20.0 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 PXF47626.1 - 0.0037 16.8 0.2 0.0083 15.7 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 PXF47626.1 - 0.0075 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 PXF47626.1 - 0.023 14.0 0.2 0.039 13.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 PXF47626.1 - 0.047 13.2 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 PXF47626.1 - 0.098 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.25 PXF47627.1 - 3.4e-13 49.9 0.0 6.3e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF47627.1 - 8.8e-10 38.6 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF47627.1 - 3.5e-09 36.5 0.0 6.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 PXF47627.1 - 2.5e-08 34.2 0.0 5.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PXF47627.1 - 0.00033 21.3 0.0 0.00044 20.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PXF47627.1 - 0.011 15.5 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PXF47627.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S9 PF00380.19 PXF47628.1 - 7.4e-32 110.4 0.1 8.5e-32 110.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAA_11 PF13086.6 PXF47631.1 - 8.4e-59 199.5 0.1 8.4e-59 199.5 0.1 3.6 5 1 0 5 5 5 1 AAA domain AAA_12 PF13087.6 PXF47631.1 - 1.5e-56 191.2 0.0 5.8e-56 189.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF47631.1 - 7.5e-07 29.0 11.9 3.2e-05 23.7 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PXF47631.1 - 2.6e-06 27.8 0.2 0.00024 21.5 0.2 3.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PXF47631.1 - 0.00024 21.0 0.0 1.5 8.5 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 PXF47631.1 - 0.074 13.3 1.0 2 8.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain PIRT PF15099.6 PXF47632.1 - 0.017 14.7 1.1 0.062 12.9 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family EXS PF03124.14 PXF47632.1 - 0.018 14.3 0.2 0.018 14.3 0.2 2.5 1 1 2 3 3 3 0 EXS family DDE_Tnp_4 PF13359.6 PXF47633.1 - 1.7e-18 66.8 0.0 4.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_Rpb2_4 PF04566.13 PXF47634.1 - 8.8e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 NIR_SIR PF01077.22 PXF47635.1 - 1.2e-54 184.1 0.0 1.9e-42 144.5 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 PXF47635.1 - 4.3e-28 97.0 0.0 1.3e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain RHH_5 PF07878.11 PXF47635.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Cupin_2 PF07883.11 PXF47636.1 - 1.5e-07 31.0 0.0 0.0027 17.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 PXF47636.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain Glycoprot_B_PH1 PF17416.2 PXF47636.1 - 0.047 13.3 0.1 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B N_formyltrans_C PF18216.1 PXF47636.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain DUF1995 PF09353.10 PXF47637.1 - 1.7e-12 47.8 0.0 2.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DNA_pol3_delta2 PF13177.6 PXF47638.1 - 1e-12 48.2 0.1 1.6e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 PXF47638.1 - 2.6e-06 27.9 0.1 6.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PXF47638.1 - 7.7e-05 22.7 0.2 0.00018 21.5 0.2 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 PXF47638.1 - 0.00025 21.5 1.7 0.0011 19.4 0.2 2.5 2 2 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 PXF47638.1 - 0.00028 21.2 0.3 0.0014 19.0 0.0 2.2 2 1 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 PXF47638.1 - 0.016 15.5 0.6 0.25 11.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 PXF47638.1 - 0.025 14.7 0.5 0.36 10.9 0.3 2.7 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 PXF47638.1 - 0.045 14.2 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 PXF47638.1 - 0.053 13.3 0.3 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 PXF47638.1 - 0.06 13.5 0.1 0.15 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PXF47638.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF1995 PF09353.10 PXF47639.1 - 6.2e-07 29.6 0.2 7.3e-07 29.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) AAA_30 PF13604.6 PXF47639.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain ATG101 PF07855.12 PXF47640.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 101 Bystin PF05291.11 PXF47640.1 - 0.16 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Bystin Milton PF12448.8 PXF47640.1 - 1 9.4 0.0 1 9.4 0.0 2.9 2 1 1 3 3 3 0 Kinesin associated protein DDE_1 PF03184.19 PXF47641.1 - 3.1e-26 92.1 0.0 6.1e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 PXF47641.1 - 6e-07 29.0 0.9 1.4e-06 27.9 0.9 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 PXF47641.1 - 0.00017 21.6 0.2 0.00033 20.7 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_Tc5 PF03221.16 PXF47641.1 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 PXF47641.1 - 0.00044 20.0 0.5 0.0011 18.7 0.5 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 PXF47641.1 - 0.00075 19.6 0.2 0.0016 18.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain STAT2_C PF12188.8 PXF47642.1 - 0.17 11.9 0.1 0.76 9.8 0.0 1.9 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal Peptidase_M1 PF01433.20 PXF47643.1 - 7.1e-37 127.1 5.3 7.1e-37 127.1 5.3 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PXF47643.1 - 8.5e-17 61.9 0.0 1.4e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 PXF47643.1 - 2.5e-11 43.8 0.5 6.2e-06 26.5 0.2 4.1 2 1 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 PXF47643.1 - 0.00079 19.9 2.1 22 6.1 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Arf PF00025.21 PXF47644.1 - 1.5e-45 154.8 0.0 1.8e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PXF47644.1 - 4.6e-12 45.7 0.0 5.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PXF47644.1 - 6.1e-07 29.7 0.0 9.6e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF47644.1 - 7.6e-06 25.6 0.0 9.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PXF47644.1 - 1.9e-05 24.0 0.1 0.0017 17.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PXF47644.1 - 0.0006 19.9 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PXF47644.1 - 0.0076 15.6 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LapA_dom PF06305.11 PXF47645.1 - 0.0052 16.6 0.6 0.0052 16.6 0.6 1.5 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain S1FA PF04689.13 PXF47645.1 - 0.021 14.9 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA CcmD PF04995.14 PXF47645.1 - 0.032 14.3 2.0 0.063 13.4 2.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1931 PF09123.11 PXF47645.1 - 0.035 14.2 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Orf78 PF06024.12 PXF47645.1 - 0.037 14.3 0.1 0.056 13.8 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TMEM100 PF16311.5 PXF47645.1 - 0.043 13.4 0.1 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Gram_pos_anchor PF00746.21 PXF47645.1 - 0.068 13.1 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FrhB_FdhB_C PF04432.13 PXF47645.1 - 0.091 12.6 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus YajC PF02699.15 PXF47645.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit FixQ PF05545.11 PXF47645.1 - 0.27 11.2 1.7 0.74 9.8 1.7 1.7 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ TMEM154 PF15102.6 PXF47645.1 - 0.37 10.7 0.6 2.7 7.9 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family PsbT PF01405.17 PXF47645.1 - 6.6 6.6 6.4 14 5.6 6.4 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Peptidase_M20 PF01546.28 PXF47646.1 - 1.5e-30 106.5 0.0 2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF47646.1 - 5.7e-19 68.0 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain UPF0016 PF01169.19 PXF47647.1 - 1.2e-41 140.9 20.2 1.4e-21 76.6 6.7 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 RRM_1 PF00076.22 PXF47648.1 - 3.4e-08 33.2 0.0 5.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon PF03129.20 PXF47648.1 - 0.00059 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain zf-met2 PF12907.7 PXF47649.1 - 5.7e-18 64.8 6.4 1e-17 64.0 6.4 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 PXF47649.1 - 0.0044 17.9 14.6 0.0044 17.9 14.6 1.8 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_4 PF13894.6 PXF47649.1 - 0.032 15.1 0.6 0.062 14.2 0.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 PXF47649.1 - 0.09 12.4 2.1 0.12 11.9 2.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type DUF1644 PF07800.12 PXF47649.1 - 0.41 10.7 7.0 1.9 8.6 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Methyltransf_21 PF05050.12 PXF47651.1 - 2.2e-09 37.6 0.0 3.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_25 PF13649.6 PXF47651.1 - 0.0019 18.9 0.0 0.013 16.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF47651.1 - 0.0036 17.2 0.0 0.0051 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PXF47651.1 - 0.03 13.2 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 PXF47651.1 - 0.055 14.1 0.0 0.43 11.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 PXF47652.1 - 4.4e-52 177.1 0.0 5.1e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47652.1 - 4e-24 85.3 0.0 5.2e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF47652.1 - 9.2e-08 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PXF47652.1 - 9.6e-08 31.2 0.0 1.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF47652.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.27 PXF47653.1 - 3.3e-21 75.8 0.8 1e-20 74.2 0.7 2.0 2 0 0 2 2 2 1 PCI domain mRNA_stabil PF13929.6 PXF47653.1 - 0.0061 15.6 0.1 0.013 14.5 0.1 1.5 1 0 0 1 1 1 1 mRNA stabilisation GCP_N_terminal PF17681.1 PXF47653.1 - 0.0064 16.2 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal TPR_7 PF13176.6 PXF47653.1 - 0.058 13.5 0.1 45 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 PXF47654.1 - 4e-78 262.4 0.0 4.9e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47654.1 - 2e-38 132.2 0.0 2.6e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF47654.1 - 2.5e-06 27.0 0.0 2.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PXF47654.1 - 0.0047 16.3 1.2 0.0063 15.9 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF47654.1 - 0.0047 16.5 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PACT_coil_coil PF10495.9 PXF47654.1 - 0.029 14.9 0.3 0.062 13.9 0.3 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Lipase_3 PF01764.25 PXF47655.1 - 3.6e-26 91.7 0.0 7.5e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PXF47655.1 - 0.002 18.8 0.1 0.0054 17.4 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF47655.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 PXF47655.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DIOX_N PF14226.6 PXF47656.1 - 2.6e-14 54.0 0.0 5.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PXF47656.1 - 4.1e-12 46.5 0.0 6.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ERM PF00769.19 PXF47657.1 - 0.0015 18.4 7.1 0.0018 18.2 7.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 PXF47657.1 - 0.0083 16.1 10.8 0.011 15.7 10.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 PXF47657.1 - 0.087 12.5 9.1 0.2 11.3 9.1 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 PXF47657.1 - 0.094 12.3 8.9 0.13 11.9 8.2 1.5 1 1 1 2 2 2 0 Intermediate filament protein DUF5344 PF17279.2 PXF47657.1 - 0.1 13.2 0.1 0.55 10.8 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Fez1 PF06818.15 PXF47657.1 - 0.13 12.7 6.9 0.19 12.2 6.9 1.2 1 0 0 1 1 1 0 Fez1 Anti-adapt_IraP PF10796.9 PXF47657.1 - 0.14 12.7 0.5 0.35 11.5 0.1 1.8 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein GAS PF13851.6 PXF47657.1 - 0.16 11.3 7.0 0.24 10.7 7.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PXF47657.1 - 0.42 9.4 9.4 0.55 9.0 9.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.13 PXF47657.1 - 0.6 10.2 4.2 0.51 10.4 2.9 1.4 1 1 0 1 1 1 0 DivIVA protein APG6_N PF17675.1 PXF47657.1 - 0.65 10.5 9.9 1.1 9.8 9.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region SPACA9 PF15120.6 PXF47657.1 - 0.73 9.6 4.3 1.1 9.0 4.3 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF4201 PF13870.6 PXF47657.1 - 2.2 8.0 10.3 6.2 6.5 6.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 PXF47657.1 - 2.6 8.3 10.0 2.3 8.5 8.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 PXF47657.1 - 2.9 8.0 11.2 0.079 13.0 3.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 PXF47657.1 - 3.2 6.2 9.7 4.1 5.8 9.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec8_exocyst PF04048.14 PXF47657.1 - 4.7 7.1 6.0 18 5.2 0.3 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain TPR_2 PF07719.17 PXF47659.1 - 0.017 15.2 2.6 12 6.3 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PXF47659.1 - 0.024 15.1 0.3 0.044 14.2 0.1 1.5 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 PXF47659.1 - 0.056 12.5 0.5 0.074 12.0 0.5 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.6 PXF47659.1 - 0.087 13.5 0.6 0.74 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF47659.1 - 0.11 12.4 1.0 94 3.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM189_B_dmain PF10520.9 PXF47660.1 - 4.7e-51 173.3 2.9 6.8e-51 172.8 2.9 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain TMEM223 PF14640.6 PXF47661.1 - 1.9e-05 24.9 0.0 0.0076 16.4 0.0 2.2 1 1 1 2 2 2 2 Transmembrane protein 223 Lipase_3 PF01764.25 PXF47661.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) DNA_pol_B_thumb PF14791.6 PXF47662.1 - 1.3e-18 66.9 0.1 3.3e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 PXF47662.1 - 1.4e-09 38.2 0.1 3.3e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 PXF47662.1 - 1.5e-09 38.0 0.9 2.8e-09 37.2 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 PXF47662.1 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda FAD_binding_8 PF08022.12 PXF47663.1 - 5.4e-18 65.1 0.0 1.1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PXF47663.1 - 8e-15 55.3 0.1 1.9e-07 31.4 0.0 3.3 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF47663.1 - 6.8e-11 42.4 10.0 6.8e-11 42.4 10.0 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 PXF47663.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ADH_N PF08240.12 PXF47664.1 - 0.0014 18.5 0.0 0.047 13.6 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PXF47664.1 - 0.0016 19.5 0.3 0.0034 18.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BPL_C PF02237.17 PXF47664.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain CENP-M PF11111.8 PXF47664.1 - 0.34 10.1 1.5 0.51 9.5 0.2 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) DnaJ_CXXCXGXG PF00684.19 PXF47665.1 - 0.00062 20.1 15.0 0.0049 17.2 15.0 2.3 1 1 0 1 1 1 1 DnaJ central domain zf-RING_9 PF13901.6 PXF47665.1 - 0.074 13.0 2.8 0.093 12.7 2.8 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF5351 PF17302.2 PXF47665.1 - 0.26 11.5 10.6 15 5.9 0.5 3.8 2 1 1 3 3 3 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 PXF47665.1 - 0.33 11.0 14.7 20 5.2 1.0 3.2 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 PXF47665.1 - 1 9.5 12.0 3 8.1 4.1 2.9 1 1 2 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 PXF47665.1 - 1.6 8.5 7.9 1.5 8.6 0.4 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 PXF47665.1 - 2 7.9 9.4 2.2 7.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 PXF47665.1 - 2.7 8.3 10.6 1.1 9.6 0.3 3.1 3 1 0 3 3 3 0 zinc-ribbon Zn_Tnp_IS91 PF14319.6 PXF47665.1 - 2.8 8.0 8.5 8.6 6.5 8.5 1.8 1 1 0 1 1 1 0 Transposase zinc-binding domain CBM_20 PF00686.19 PXF47666.1 - 5e-37 125.7 0.0 3.5e-14 52.5 0.0 3.3 3 0 0 3 3 3 3 Starch binding domain DSPc PF00782.20 PXF47666.1 - 4e-18 65.5 0.0 6.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PXF47666.1 - 0.003 17.6 0.1 0.0046 17.0 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 PXF47666.1 - 0.004 16.9 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 PXF47666.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain WD40 PF00400.32 PXF47667.1 - 2.2e-29 101.1 18.2 5e-09 36.6 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF2259 PF10016.9 PXF47667.1 - 0.0033 17.4 0.1 0.012 15.5 0.1 2.1 1 1 0 1 1 1 1 Predicted secreted protein (DUF2259) DUF812 PF05667.11 PXF47667.1 - 0.015 14.3 6.2 0.02 13.8 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.9 PXF47667.1 - 0.039 14.3 1.7 0.076 13.3 0.9 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 PXF47667.1 - 0.051 13.6 3.9 0.09 12.8 3.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CC2-LZ PF16516.5 PXF47667.1 - 0.058 13.8 3.5 0.11 12.9 3.5 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ANAPC4_WD40 PF12894.7 PXF47667.1 - 0.064 13.6 0.1 3.1 8.2 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cep57_CLD_2 PF14197.6 PXF47667.1 - 0.085 13.0 4.5 0.2 11.8 4.5 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 VGPC1_C PF16799.5 PXF47667.1 - 0.13 12.2 0.6 0.34 10.9 0.6 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 WD40_like PF17005.5 PXF47667.1 - 0.16 11.2 0.0 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain SlyX PF04102.12 PXF47667.1 - 0.18 12.4 5.0 0.29 11.8 3.6 2.1 2 0 0 2 2 2 0 SlyX Med9 PF07544.13 PXF47667.1 - 0.19 11.9 3.3 0.35 11.0 2.5 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PQQ_3 PF13570.6 PXF47667.1 - 0.23 12.0 0.7 0.86 10.2 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain Sec8_exocyst PF04048.14 PXF47667.1 - 0.25 11.2 3.0 0.48 10.3 3.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc24 PF08286.11 PXF47667.1 - 0.56 10.5 3.2 1.4 9.2 3.2 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FAM76 PF16046.5 PXF47667.1 - 0.84 8.9 5.0 1.3 8.3 5.0 1.3 1 0 0 1 1 1 0 FAM76 protein FH2 PF02181.23 PXF47668.1 - 4.9e-64 216.8 1.8 5.9e-64 216.5 1.8 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3886 PF13025.6 PXF47668.1 - 0.0021 18.2 1.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3886) CK2S PF15011.6 PXF47668.1 - 0.0032 17.4 0.9 0.0084 16.0 0.5 1.8 2 0 0 2 2 2 1 Casein Kinase 2 substrate Prominin PF05478.11 PXF47668.1 - 1.2 7.0 3.6 0.84 7.5 0.2 1.9 2 0 0 2 2 2 0 Prominin YabA PF06156.13 PXF47668.1 - 3 8.5 5.6 0.43 11.2 0.7 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Lipoprotein_20 PF13942.6 PXF47669.1 - 0.052 13.5 2.9 0.053 13.4 1.1 1.9 2 0 0 2 2 2 0 YfhG lipoprotein Mod_r PF07200.13 PXF47669.1 - 0.066 13.3 5.2 1 9.5 3.1 2.8 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TIG PF01833.24 PXF47670.1 - 3.9e-22 78.1 9.8 1.4e-12 47.5 0.3 2.9 3 0 0 3 3 3 2 IPT/TIG domain GSDH PF07995.11 PXF47670.1 - 6.6e-07 29.0 0.4 1.8e-06 27.5 0.4 1.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF3689 PF12463.8 PXF47671.1 - 5.3e-48 163.9 1.7 7.7e-41 140.4 0.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) Cohesin_HEAT PF12765.7 PXF47671.1 - 3 8.2 5.6 1.8 8.9 0.4 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion AMP-binding PF00501.28 PXF47672.1 - 5.5e-95 318.4 0.0 9.5e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme BST2 PF16716.5 PXF47672.1 - 0.076 13.6 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Cofac_haem_bdg PF04187.13 PXF47673.1 - 8.7e-44 150.1 0.0 1.2e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN TAT_signal PF10518.9 PXF47673.1 - 0.054 13.3 0.6 0.13 12.2 0.6 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DRMBL PF07522.14 PXF47675.1 - 5.1e-19 68.5 0.0 6.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 PXF47675.1 - 0.00039 20.3 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DUF885 PF05960.11 PXF47677.1 - 0.051 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) APAF1_C PF17908.1 PXF47679.1 - 0.11 12.5 0.1 0.83 9.7 0.0 2.0 2 0 0 2 2 2 0 APAF-1 helical domain SHOCT PF09851.9 PXF47680.1 - 7.8e-05 22.3 1.7 7.8e-05 22.3 1.7 1.8 2 0 0 2 2 2 1 Short C-terminal domain DUF1707 PF08044.11 PXF47680.1 - 0.00056 19.9 0.5 0.00094 19.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) Cwf_Cwc_15 PF04889.12 PXF47680.1 - 0.43 10.3 8.5 0.63 9.7 8.5 1.2 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 PXF47680.1 - 2.5 6.2 8.3 2.8 6.0 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 PXF47680.1 - 5.2 6.1 11.0 7.9 5.5 11.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2985 PF11204.8 PXF47681.1 - 0.38 10.9 2.9 7.1 6.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) TPR_14 PF13428.6 PXF47683.1 - 2.9e-28 96.1 45.2 0.00043 20.9 2.7 12.4 5 3 8 13 13 13 10 Tetratricopeptide repeat TPR_19 PF14559.6 PXF47683.1 - 4.9e-25 87.8 16.1 0.00072 20.0 0.1 7.8 6 1 1 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 PXF47683.1 - 8.2e-22 77.6 45.4 0.0033 18.0 0.5 9.5 5 4 4 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 PXF47683.1 - 1.8e-20 71.3 16.0 0.014 15.5 0.0 11.7 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 PXF47683.1 - 9.8e-15 53.8 16.1 0.11 12.9 0.0 10.6 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF47683.1 - 1.2e-10 41.5 34.5 4.9e-06 26.7 0.5 8.8 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF47683.1 - 1.3e-10 40.6 0.5 2.5 8.5 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF47683.1 - 4e-10 39.4 26.4 9.7e-05 21.7 3.6 5.6 1 1 4 5 5 5 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF47683.1 - 5.1e-10 39.4 8.0 0.44 10.5 0.0 7.8 8 2 2 10 10 9 3 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 PXF47683.1 - 1.6e-09 37.8 20.5 0.0041 17.2 1.1 7.0 4 1 2 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 PXF47683.1 - 9.6e-09 35.6 0.0 0.0012 18.9 0.0 3.0 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_7 PF13176.6 PXF47683.1 - 4.3e-08 32.6 11.0 0.15 12.2 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF47683.1 - 5e-07 29.3 5.7 0.18 11.5 0.0 6.4 8 0 0 8 8 7 1 TPR repeat TPR_6 PF13174.6 PXF47683.1 - 2.9e-06 27.5 20.7 1.2 9.9 0.1 10.4 12 1 0 12 12 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF47683.1 - 3.2e-06 26.7 9.7 0.32 10.9 0.0 7.5 10 0 0 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF47683.1 - 2.5e-05 24.4 7.6 1.7 8.9 0.4 5.3 4 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NRDE-2 PF08424.10 PXF47683.1 - 0.00014 21.1 1.7 0.0012 18.0 0.0 2.9 2 1 1 3 3 3 1 NRDE-2, necessary for RNA interference PPR PF01535.20 PXF47683.1 - 0.00021 21.3 0.3 63 4.1 0.0 6.2 7 0 0 7 7 7 0 PPR repeat NARP1 PF12569.8 PXF47683.1 - 0.0026 16.8 0.5 2.1 7.2 0.1 3.1 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 PXF47683.1 - 0.013 15.5 0.7 49 4.1 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat HAT PF02184.16 PXF47683.1 - 0.015 15.3 7.0 17 5.5 0.1 5.9 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DUF4075 PF13294.6 PXF47683.1 - 0.03 14.5 1.2 17 5.7 0.0 4.4 7 0 0 7 7 3 0 Domain of unknown function (DUF4075) MIT PF04212.18 PXF47683.1 - 0.054 13.6 9.4 20 5.3 0.0 6.2 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.7 PXF47683.1 - 0.15 12.4 3.3 2.5 8.4 0.2 3.3 3 1 0 3 3 2 0 Tetratrico peptide repeat TPR_21 PF09976.9 PXF47683.1 - 0.92 9.2 18.9 7.3 6.2 0.6 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain HEPN_SAV_6107 PF18726.1 PXF47683.1 - 3 8.4 15.7 1 9.9 0.8 4.4 3 1 1 4 4 3 0 SAV_6107-like HEPN CoA_binding PF02629.19 PXF47684.1 - 8.6e-25 87.3 0.4 8.6e-25 87.3 0.4 2.2 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 PXF47684.1 - 1.6e-23 83.2 0.4 2.8e-23 82.4 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PXF47684.1 - 9.2e-10 38.5 0.1 1.7e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 PXF47684.1 - 0.00015 22.2 0.0 0.0007 20.1 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain DUF1611_N PF17396.2 PXF47684.1 - 0.18 12.1 0.5 3.8 7.8 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain NAM-associated PF14303.6 PXF47686.1 - 7.9e-08 33.2 0.9 1.7e-07 32.2 0.1 1.9 1 1 1 2 2 2 1 No apical meristem-associated C-terminal domain Hydrolase_4 PF12146.8 PXF47691.1 - 4.5e-11 42.5 2.3 7.4e-10 38.5 2.3 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF47691.1 - 6.3e-11 42.4 0.1 4.5e-06 26.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF47691.1 - 3e-09 37.8 0.0 4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 PXF47691.1 - 3.5e-05 23.9 0.7 0.0021 18.1 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_2 PF02230.16 PXF47691.1 - 0.0061 16.4 0.1 0.068 13.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 PXF47691.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.12 PXF47691.1 - 0.037 14.0 0.4 0.084 12.8 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 PXF47691.1 - 0.056 12.8 0.2 1.5 8.1 0.2 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 PXF47691.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family CbiG_N PF11760.8 PXF47691.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.6 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal EzrA PF06160.12 PXF47693.1 - 0.018 13.3 1.8 0.024 12.8 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF47693.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF47693.1 - 4.6 7.9 13.5 0.76 10.5 6.5 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Plant_tran PF04827.14 PXF47694.1 - 1.4e-52 178.3 0.0 2.1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF47694.1 - 4.3e-13 49.2 0.0 1e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease RNase_H2-Ydr279 PF09468.10 PXF47694.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Peptidase_S8 PF00082.22 PXF47696.1 - 7.8e-33 114.0 4.9 1.4e-32 113.2 4.9 1.3 1 1 0 1 1 1 1 Subtilase family DUF4684 PF15736.5 PXF47696.1 - 0.025 13.3 6.1 0.044 12.5 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) MtrB_PioB PF11854.8 PXF47697.1 - 0.071 11.4 0.2 0.13 10.6 0.1 1.4 2 0 0 2 2 2 0 Putative outer membrane beta-barrel porin, MtrB/PioB Lyase_1 PF00206.20 PXF47698.1 - 1.8e-111 372.5 0.0 2.5e-111 372.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PXF47698.1 - 4.8e-23 81.3 0.1 1.2e-22 80.0 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus CBFD_NFYB_HMF PF00808.23 PXF47700.1 - 1.4e-15 57.3 0.9 1.9e-15 56.9 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF47700.1 - 1.4e-06 28.7 0.5 1.4e-06 28.7 0.5 2.7 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 Spt20 PF12090.8 PXF47700.1 - 0.073 12.7 9.3 0.099 12.2 9.3 1.2 1 0 0 1 1 1 0 Spt20 family SAPS PF04499.15 PXF47700.1 - 0.12 11.1 1.3 0.14 10.9 1.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RXT2_N PF08595.11 PXF47700.1 - 0.34 10.9 5.0 0.59 10.2 5.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 PXF47700.1 - 2.9 7.5 4.9 5 6.8 4.9 1.4 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 PXF47700.1 - 7.3 5.2 5.3 9.3 4.9 5.3 1.3 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 PXF47701.1 - 4.9e-47 159.9 0.0 1e-46 158.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF47701.1 - 2.6e-28 98.6 0.0 9.1e-28 96.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 PXF47701.1 - 6.4e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 PXF47701.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PXF47701.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 PXF47701.1 - 0.19 11.0 0.0 0.46 9.7 0.0 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain GATA PF00320.27 PXF47702.1 - 1.7e-07 30.7 9.3 2.9e-07 30.0 9.3 1.4 1 0 0 1 1 1 1 GATA zinc finger ADK_lid PF05191.14 PXF47702.1 - 0.15 12.1 0.4 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid GATA PF00320.27 PXF47703.1 - 2.6e-07 30.1 8.1 4.3e-07 29.4 8.1 1.4 1 0 0 1 1 1 1 GATA zinc finger SPAR_C PF11881.8 PXF47703.1 - 0.016 15.1 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 C-terminal domain of SPAR protein DDE_Tnp_4 PF13359.6 PXF47704.1 - 2.5e-15 56.5 0.0 3.7e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-H2C2_2 PF13465.6 PXF47706.1 - 2.5e-12 46.6 41.5 0.00021 21.5 0.8 5.4 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 PXF47706.1 - 3e-12 46.3 38.6 0.002 18.5 3.7 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF47706.1 - 1.5e-11 44.1 38.2 0.0031 18.2 2.3 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF47706.1 - 0.00012 21.8 4.6 0.00012 21.8 4.6 4.7 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 PXF47706.1 - 0.0047 17.6 14.8 4.7 7.9 9.5 4.3 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 PXF47706.1 - 0.0064 16.6 15.6 0.28 11.3 2.7 3.5 2 1 1 3 3 3 2 Zinc ribbon domain ADK_lid PF05191.14 PXF47706.1 - 0.016 15.2 7.7 0.34 10.9 0.7 2.8 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 PXF47706.1 - 0.019 14.5 12.5 0.22 11.1 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger IBD PF10416.9 PXF47706.1 - 0.021 14.8 0.2 0.042 13.9 0.0 1.6 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD C1_1 PF00130.22 PXF47706.1 - 0.045 13.7 14.6 0.32 10.9 2.9 3.5 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-trcl PF13451.6 PXF47706.1 - 0.11 12.4 15.4 0.5 10.3 3.4 3.0 2 1 0 2 2 2 0 Probable zinc-ribbon domain Fer4_10 PF13237.6 PXF47706.1 - 0.12 12.5 7.5 3.8 7.7 0.3 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-C2HE PF16278.5 PXF47706.1 - 0.43 11.0 0.3 0.43 11.0 0.3 4.0 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 PXF47706.1 - 0.64 10.2 16.7 3.4 7.9 0.2 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger zf-Sec23_Sec24 PF04810.15 PXF47706.1 - 0.92 9.6 11.9 2.8 8.1 0.4 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-C2H2_8 PF15909.5 PXF47706.1 - 1.1 9.6 19.0 2.5 8.4 6.4 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon Fer4_9 PF13187.6 PXF47706.1 - 2.1 8.6 12.1 2e+03 -0.9 12.1 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain C1_2 PF03107.16 PXF47706.1 - 2.4 8.5 18.4 2.7 8.4 6.3 4.0 1 1 2 3 3 3 0 C1 domain OrfB_Zn_ribbon PF07282.11 PXF47706.1 - 7.3 6.6 16.2 6.6 6.7 3.7 3.7 2 1 2 4 4 4 0 Putative transposase DNA-binding domain ThiF PF00899.21 PXF47707.1 - 2.8e-06 26.9 0.0 8.1e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 ThiF family ABC_tran PF00005.27 PXF47708.1 - 1.7e-34 119.3 0.0 3.3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PXF47708.1 - 2.5e-29 102.8 9.1 3.8e-29 102.2 9.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 PXF47708.1 - 4.9e-07 30.3 0.2 1.1e-06 29.2 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PXF47708.1 - 0.00028 21.2 0.1 0.00089 19.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PXF47708.1 - 0.00066 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PXF47708.1 - 0.0027 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 PXF47708.1 - 0.004 16.6 0.4 0.21 11.0 0.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 PXF47708.1 - 0.0063 16.3 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PXF47708.1 - 0.011 15.9 0.1 0.023 14.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF47708.1 - 0.013 15.5 0.2 0.11 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 PXF47708.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PXF47708.1 - 0.046 14.1 0.2 0.66 10.4 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PXF47708.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PXF47708.1 - 0.097 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 PXF47708.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 PXF47708.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 PXF47708.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 PXF47708.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 PXF47708.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0258 PF06789.12 PXF47709.1 - 0.12 12.5 0.5 0.16 12.1 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) SAM_decarbox PF01536.16 PXF47711.1 - 1.7e-79 267.5 0.3 2.2e-79 267.1 0.3 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Orn_DAP_Arg_deC PF00278.22 PXF47711.1 - 3.3e-06 27.2 0.0 4.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 PXF47711.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain AdoMet_dc PF02675.15 PXF47711.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase FeoB_C PF07664.12 PXF47712.1 - 0.046 13.4 0.2 0.046 13.4 0.2 3.4 5 0 0 5 5 5 0 Ferrous iron transport protein B C terminus DUF3792 PF12670.7 PXF47712.1 - 0.17 12.0 18.4 0.14 12.3 3.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) TRP PF06011.12 PXF47712.1 - 0.8 8.4 8.2 0.14 10.8 3.3 2.1 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Colicin_V PF02674.16 PXF47712.1 - 1.2 9.2 11.3 0.16 11.9 3.3 2.7 3 0 0 3 3 3 0 Colicin V production protein DUF2070 PF09843.9 PXF47712.1 - 4.7 5.4 10.3 6.4 4.9 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 PXF47712.1 - 8.5 6.0 15.3 84 2.8 9.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HNH_5 PF14279.6 PXF47713.1 - 5.7e-17 61.3 0.6 9.7e-17 60.6 0.6 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 PXF47713.1 - 1.5e-13 50.6 1.0 2.3e-13 50.1 1.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 PXF47713.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease zf-C2HC_2 PF13913.6 PXF47713.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 PXF47713.1 - 0.032 14.7 0.2 0.081 13.4 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf_C2H2_6 PF18450.1 PXF47713.1 - 0.091 12.5 0.2 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Zinc Finger domain zf-C2H2_4 PF13894.6 PXF47713.1 - 0.11 13.4 0.2 0.37 11.8 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-CHCC PF10276.9 PXF47713.1 - 0.23 11.6 1.3 0.59 10.2 1.3 1.7 1 0 0 1 1 1 0 Zinc-finger domain ABC1 PF03109.16 PXF47714.1 - 2.4e-35 121.2 0.0 6.1e-35 120.0 0.0 1.7 2 0 0 2 2 2 1 ABC1 family HTH_42 PF06224.12 PXF47716.1 - 3.3e-32 112.4 3.5 5.2e-32 111.7 3.5 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Ribonucleas_3_3 PF14622.6 PXF47717.1 - 4.1e-08 33.4 0.0 2.4e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PXF47717.1 - 7.4e-07 29.8 0.0 2.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain HTH_42 PF06224.12 PXF47719.1 - 1.2e-18 67.8 1.3 1.9e-18 67.1 1.3 1.3 1 1 0 1 1 1 1 Winged helix DNA-binding domain RecR PF02132.15 PXF47720.1 - 0.08 12.5 3.4 2.3 7.8 0.4 2.3 2 0 0 2 2 2 0 RecR protein AIG1 PF04548.16 PXF47721.1 - 6.1e-08 32.2 1.3 3.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 PXF47721.1 - 0.00041 20.8 0.4 0.0023 18.3 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 PXF47721.1 - 0.008 16.7 3.3 0.4 11.2 0.0 3.8 3 1 1 4 4 4 1 AAA domain NACHT PF05729.12 PXF47721.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 PXF47721.1 - 0.015 15.6 0.6 0.054 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PXF47721.1 - 0.021 15.3 1.3 0.26 11.8 0.0 2.9 4 0 0 4 4 4 0 ABC transporter NTPase_1 PF03266.15 PXF47721.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 PXF47721.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PXF47721.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 PXF47721.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 PXF47721.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PXF47721.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NAD_binding_3 PF03447.16 PXF47721.1 - 0.14 12.8 0.1 0.4 11.4 0.1 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_23 PF13476.6 PXF47721.1 - 2.8 8.4 0.0 2.8 8.4 0.0 2.9 2 1 0 2 2 1 0 AAA domain SYS1 PF09801.9 PXF47722.1 - 1.4e-29 103.1 5.2 1.6e-29 102.9 5.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF3397 PF11877.8 PXF47722.1 - 0.8 9.9 11.0 1.6 9.0 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) Glycos_transf_1 PF00534.20 PXF47723.1 - 2.9e-24 85.5 0.0 7.7e-24 84.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF47723.1 - 6.2e-19 68.8 0.1 2e-18 67.1 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1752 PF08550.10 PXF47723.1 - 1.9e-13 49.9 2.2 4.5e-13 48.8 2.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_trans_1_2 PF13524.6 PXF47723.1 - 1.8e-10 41.0 0.2 1.5e-09 38.1 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF47723.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HEPN_RnaseLS PF18869.1 PXF47723.1 - 0.073 13.2 1.3 0.16 12.0 0.3 2.1 2 0 0 2 2 2 0 RnaseLS-like HEPN CDC73_C PF05179.14 PXF47724.1 - 6.9e-33 113.6 0.1 2e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 PXF47724.1 - 7.7e-06 25.4 0.6 1.2e-05 24.8 0.6 1.4 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal TIG PF01833.24 PXF47725.1 - 7.1e-15 54.9 23.3 1.5e-10 41.0 1.4 4.7 5 0 0 5 5 5 2 IPT/TIG domain GSDH PF07995.11 PXF47725.1 - 1.3e-05 24.7 0.0 0.0045 16.3 0.0 2.5 2 1 0 2 2 2 2 Glucose / Sorbosone dehydrogenase Apolipoprotein PF01442.18 PXF47726.1 - 2.7e-06 27.4 9.4 4.2e-05 23.5 2.3 3.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Malectin PF11721.8 PXF47727.1 - 4.5e-39 134.2 0.0 4.1e-13 49.8 0.0 3.5 3 0 0 3 3 3 3 Malectin domain TIG PF01833.24 PXF47727.1 - 1.4e-13 50.7 20.8 6e-09 35.9 0.5 4.6 5 0 0 5 5 5 2 IPT/TIG domain Malectin_like PF12819.7 PXF47727.1 - 1.7e-06 27.5 0.0 0.03 13.5 0.0 2.7 2 1 0 2 2 2 2 Malectin-like domain GSDH PF07995.11 PXF47727.1 - 5e-05 22.8 0.0 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase Pkinase PF00069.25 PXF47728.1 - 7.9e-24 84.4 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PXF47728.1 - 1.7e-07 30.4 2.4 1.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase_Tyr PF07714.17 PXF47728.1 - 5.2e-07 29.2 0.0 7.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S7e PF01251.18 PXF47728.1 - 0.053 13.3 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e YrbL-PhoP_reg PF10707.9 PXF47728.1 - 0.1 12.1 0.2 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Glyco_hydro_43 PF04616.14 PXF47729.1 - 7.3e-28 97.7 2.1 9e-28 97.4 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase PF00069.25 PXF47730.1 - 4.3e-56 190.2 0.0 1.8e-33 116.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47730.1 - 5.3e-31 107.8 0.0 7.6e-23 81.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PXF47730.1 - 1.5e-07 31.0 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PXF47730.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF47730.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PXF47730.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_tranf_2_2 PF10111.9 PXF47731.1 - 1.7e-06 27.7 0.0 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 PXF47731.1 - 0.00032 20.3 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 PXF47731.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF47731.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 UVR PF02151.19 PXF47732.1 - 5.8e-05 22.7 15.2 0.00043 19.9 2.6 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif PD40 PF07676.12 PXF47732.1 - 0.011 15.7 12.8 2.8 8.0 0.1 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 PXF47732.1 - 0.1 11.4 0.6 16 4.1 0.0 3.6 3 1 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Senescence PF06911.12 PXF47733.1 - 7.1e-08 33.0 8.7 7.6e-08 32.9 6.7 2.0 1 1 1 2 2 2 1 Senescence-associated protein AIG2_2 PF13772.6 PXF47734.1 - 9.2e-10 38.8 0.1 1.8e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 AIG2-like family ChaC PF04752.12 PXF47734.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 PXF47734.1 - 0.00062 20.4 0.2 0.0019 18.8 0.0 1.9 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2615 PF11027.8 PXF47734.1 - 0.033 14.3 0.7 0.12 12.5 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) NAD_binding_1 PF00175.21 PXF47735.1 - 4.5e-16 59.4 0.0 7.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PXF47735.1 - 0.032 14.3 0.0 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DnaJ PF00226.31 PXF47736.1 - 5e-23 81.0 0.6 5e-23 81.0 0.6 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 PXF47736.1 - 2.5e-09 37.2 6.3 1.1e-07 32.0 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PXF47736.1 - 6.3e-06 26.5 9.8 0.0056 17.0 0.7 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PXF47736.1 - 8.6e-05 22.8 6.4 0.00021 21.6 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PXF47736.1 - 0.00094 19.8 3.3 0.027 15.3 0.5 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PXF47736.1 - 0.0022 17.9 3.9 0.006 16.6 0.4 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF47736.1 - 0.0024 18.2 6.1 0.0091 16.4 0.9 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Ribosomal_L37 PF08561.10 PXF47737.1 - 3.2e-07 30.9 9.7 3.1e-05 24.5 9.7 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF3283 PF11686.8 PXF47737.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) DUF499 PF04465.12 PXF47737.1 - 0.12 10.1 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF499) Pkinase PF00069.25 PXF47738.1 - 7.2e-58 196.0 0.0 9e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47738.1 - 9.1e-40 136.6 0.0 1.3e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF47738.1 - 6.4e-05 21.9 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF47738.1 - 0.00015 21.8 0.1 0.23 11.4 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF47738.1 - 0.0038 16.6 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SF1-HH PF16275.5 PXF47738.1 - 0.0067 16.8 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain LupA PF18242.1 PXF47738.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Abi_2 PF07751.11 PXF47738.1 - 0.071 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Abi-like protein Kdo PF06293.14 PXF47738.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_C PF00137.21 PXF47739.1 - 1.1e-34 118.6 35.0 3.8e-21 75.2 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF4389 PF14333.6 PXF47739.1 - 2.3 8.2 8.4 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) ARID PF01388.21 PXF47740.1 - 9.1e-13 48.7 0.0 2.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3886 PF13025.6 PXF47740.1 - 0.056 13.6 3.2 0.19 11.9 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Helicase_C_2 PF13307.6 PXF47742.1 - 9.4e-46 156.1 0.2 2.2e-45 154.9 0.2 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PXF47742.1 - 4e-42 143.8 0.1 7.7e-42 142.9 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 PXF47742.1 - 6.4e-06 26.3 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF47742.1 - 0.0059 16.4 0.4 0.27 11.0 0.1 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase PhoH PF02562.16 PXF47742.1 - 0.032 13.7 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein tRNA-synt_2c PF01411.19 PXF47744.1 - 9.9e-192 638.3 0.0 1.2e-191 638.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 PXF47744.1 - 7e-18 65.4 6.1 7e-18 65.4 6.1 2.1 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 PXF47744.1 - 3.5e-17 62.2 0.4 1e-16 60.8 0.4 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF4795 PF16043.5 PXF47744.1 - 0.0083 15.7 2.3 0.92 9.1 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) BCMA-Tall_bind PF09257.10 PXF47744.1 - 0.077 13.1 1.6 0.18 11.9 1.6 1.5 1 0 0 1 1 1 0 BCMA, TALL-1 binding Baculo_PEP_C PF04513.12 PXF47744.1 - 0.31 11.1 1.3 14 5.7 0.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 PXF47744.1 - 0.37 10.6 2.4 0.71 9.7 2.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 HisKA PF00512.25 PXF47744.1 - 0.44 10.6 1.7 1 9.5 0.3 2.4 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain ZapB PF06005.12 PXF47744.1 - 1.7 9.1 4.3 26 5.4 0.5 2.7 2 0 0 2 2 2 0 Cell division protein ZapB bHLH-MYC_N PF14215.6 PXF47745.1 - 6.6e-05 23.3 0.0 0.36 11.1 0.0 2.3 1 1 1 2 2 2 2 bHLH-MYC and R2R3-MYB transcription factors N-terminal HLH PF00010.26 PXF47745.1 - 0.00073 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAF_2 PF13185.6 PXF47745.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain RRM_1 PF00076.22 PXF47746.1 - 2.9e-14 52.6 0.1 6.5e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF47746.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 PXF47746.1 - 0.11 12.7 2.5 0.35 11.1 0.1 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ndc1_Nup PF09531.10 PXF47746.1 - 0.24 10.0 5.8 0.27 9.9 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAF PF01590.26 PXF47747.1 - 2e-06 28.5 0.4 9.7e-06 26.2 0.1 2.2 1 1 1 2 2 2 1 GAF domain GAF_2 PF13185.6 PXF47747.1 - 5.9e-06 26.6 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain SUIM_assoc PF16619.5 PXF47747.1 - 0.006 16.6 1.7 0.025 14.6 1.7 2.1 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 GAF_3 PF13492.6 PXF47747.1 - 0.0094 16.3 0.4 0.028 14.8 0.1 2.0 2 0 0 2 2 2 1 GAF domain bHLH-MYC_N PF14215.6 PXF47747.1 - 0.075 13.3 0.4 3.6 7.8 0.0 2.6 1 1 1 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal TFIIA PF03153.13 PXF47747.1 - 8.6 6.2 15.8 2.8 7.8 0.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC_tran_Xtn PF12848.7 PXF47748.1 - 0.063 13.3 0.7 0.1 12.6 0.7 1.3 1 0 0 1 1 1 0 ABC transporter NOG1_N PF17835.1 PXF47749.1 - 2.9e-53 180.1 0.1 2.9e-53 180.1 0.1 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 PXF47749.1 - 9e-28 95.8 0.0 1.8e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 PXF47749.1 - 3.5e-25 87.7 0.7 6.4e-25 86.9 0.7 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 PXF47749.1 - 6.1e-18 65.0 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF47749.1 - 1.8e-08 34.1 0.0 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 PXF47749.1 - 0.00092 18.6 0.4 0.0092 15.3 0.0 2.5 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 PXF47749.1 - 0.024 15.0 1.3 0.28 11.5 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 PXF47749.1 - 0.047 13.9 0.0 0.47 10.7 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PXF47749.1 - 0.052 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PXF47749.1 - 0.062 13.2 0.3 1.2 9.0 0.0 3.0 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 PXF47749.1 - 0.079 13.0 0.0 3.5 7.7 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Mal_decarbox_Al PF16957.5 PXF47749.1 - 0.1 10.9 0.1 0.15 10.3 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Ribosomal_S8 PF00410.19 PXF47751.1 - 3.1e-34 117.7 0.0 3.4e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 REJ PF02010.15 PXF47752.1 - 1.6e-23 83.3 6.6 2.8e-22 79.2 1.4 2.3 2 0 0 2 2 2 2 REJ domain CRPA PF05745.11 PXF47752.1 - 0.09 12.8 1.8 0.16 12.0 0.5 2.1 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Epimerase PF01370.21 PXF47753.1 - 1.3e-15 57.5 0.0 1.7e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PXF47753.1 - 2.5e-10 40.5 0.0 8.3e-10 38.8 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PXF47753.1 - 3e-10 40.1 0.0 8.2e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 PXF47753.1 - 3.3e-10 39.9 0.0 0.00012 21.6 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PXF47753.1 - 7.2e-08 31.9 0.0 1.5e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PXF47753.1 - 0.00063 18.8 0.0 0.076 12.0 0.0 2.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mur_ligase PF01225.25 PXF47753.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain B12D PF06522.11 PXF47754.1 - 3.9e-07 29.8 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit WD40 PF00400.32 PXF47756.1 - 0.005 17.7 1.0 0.034 15.0 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Acyl_transf_1 PF00698.21 PXF47757.1 - 4.9e-28 98.6 1.2 5.6e-28 98.4 1.2 1.0 1 0 0 1 1 1 1 Acyl transferase domain Ribosomal_L18A PF01775.17 PXF47758.1 - 3.5e-48 162.7 0.2 4.4e-48 162.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A MitMem_reg PF13012.6 PXF47759.1 - 2.4e-31 108.5 0.1 4e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PXF47759.1 - 3.2e-27 94.8 0.0 5.3e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MOSC_N PF03476.16 PXF47760.1 - 2e-12 47.0 0.1 6.7e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain DUF4035 PF13227.6 PXF47760.1 - 0.065 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) GOLD_2 PF13897.6 PXF47760.1 - 1.4 9.4 7.4 6.7 7.2 0.3 2.7 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking TMP-TENI PF02581.17 PXF47761.1 - 2.6e-50 170.2 3.4 3.2e-50 170.0 3.4 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase CutC PF03932.14 PXF47761.1 - 0.00012 21.7 0.3 0.00041 19.9 0.3 1.9 1 1 0 1 1 1 1 CutC family NMO PF03060.15 PXF47761.1 - 0.0013 18.2 1.1 0.0015 17.9 1.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 PXF47761.1 - 0.0056 15.9 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF561 PF04481.12 PXF47761.1 - 0.0076 15.4 1.1 0.082 12.1 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF561) IGPS PF00218.21 PXF47761.1 - 0.015 14.5 0.1 0.034 13.3 0.1 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase ThiG PF05690.14 PXF47761.1 - 0.073 12.4 1.2 0.11 11.8 1.2 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PARP PF00644.20 PXF47762.1 - 4.3e-36 124.3 1.0 6.9e-36 123.7 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 PXF47762.1 - 6e-21 74.3 0.0 1.9e-07 31.0 0.0 3.5 3 0 0 3 3 3 3 WGR domain PARP_reg PF02877.14 PXF47762.1 - 3.9e-20 72.3 0.0 7.2e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain DUF5073 PF16817.5 PXF47762.1 - 0.0071 16.4 0.6 0.046 13.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5073) WWE PF02825.20 PXF47762.1 - 0.14 12.7 0.3 0.58 10.8 0.4 2.1 2 0 0 2 2 2 0 WWE domain Tfb2_C PF18307.1 PXF47763.1 - 0.14 12.6 0.7 15 6.1 0.2 2.8 2 1 1 3 3 3 0 Transcription factor Tfb2 (p52) C-terminal domain DUF2254 PF10011.9 PXF47764.1 - 0.0038 16.1 0.2 0.0068 15.3 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sid-5 PF17204.3 PXF47764.1 - 0.03 14.5 1.1 0.03 14.5 1.1 1.9 3 0 0 3 3 3 0 Sid-5 family Mlh1_C PF16413.5 PXF47765.1 - 4.2e-45 154.2 0.0 9.7e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 PXF47765.1 - 3.4e-24 84.8 0.0 5.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PXF47765.1 - 1.2e-13 51.0 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PXF47765.1 - 1.4e-07 32.0 0.0 3.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GcrA PF07750.11 PXF47766.1 - 0.031 14.7 0.4 0.053 13.9 0.4 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator Helicase_C_2 PF13307.6 PXF47766.1 - 0.034 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF913 PF06025.12 PXF47766.1 - 0.16 10.9 0.6 1.6 7.7 0.0 2.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) APG6_N PF17675.1 PXF47766.1 - 0.23 12.0 14.3 0.89 10.1 14.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region AAA_23 PF13476.6 PXF47766.1 - 0.37 11.3 5.3 0.43 11.1 5.3 1.2 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 PXF47766.1 - 1.3 9.2 15.1 0.036 14.3 5.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Complex1_LYR PF05347.15 PXF47767.1 - 5.9e-12 45.5 1.1 1.1e-11 44.6 1.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PXF47767.1 - 0.003 18.3 0.3 0.0034 18.1 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PXF47767.1 - 0.015 15.8 0.2 0.024 15.2 0.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like dCMP_cyt_deam_1 PF00383.23 PXF47768.1 - 1.8e-10 40.6 1.9 3.2e-10 39.8 1.9 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF47768.1 - 3.9e-06 26.6 0.1 1.2e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 MafB19-like deaminase LSM PF01423.22 PXF47769.1 - 2.9e-16 58.9 0.1 4.7e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 LSM domain WD40 PF00400.32 PXF47770.1 - 5.6e-13 49.1 10.2 0.00032 21.4 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 PXF47770.1 - 0.00031 19.5 0.2 0.00087 18.1 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PXF47770.1 - 0.00039 20.7 0.3 0.0062 16.8 0.3 2.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain UPF0004 PF00919.20 PXF47772.1 - 2.4e-26 91.7 0.2 1.3e-25 89.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PXF47772.1 - 3e-26 92.8 0.1 5.6e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 PXF47772.1 - 1.6e-12 47.2 0.1 3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 TRAM domain Rotamase PF00639.21 PXF47772.1 - 1.1e-05 26.3 0.0 3.9e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PXF47772.1 - 5.7e-05 23.6 0.0 0.00019 21.9 0.0 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain TRAM_2 PF18693.1 PXF47772.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.9 1 1 0 1 1 1 0 TRAM domain MttA_Hcf106 PF02416.16 PXF47773.1 - 4e-09 35.7 8.2 1.3e-08 34.0 8.2 1.9 1 1 0 1 1 1 1 mttA/Hcf106 family Pkinase PF00069.25 PXF47774.1 - 8.9e-62 208.8 0.0 1.1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47774.1 - 9.9e-38 129.9 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF47774.1 - 1.9e-05 23.6 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PXF47774.1 - 3.9e-05 23.1 0.1 6.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 PXF47774.1 - 0.037 13.0 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 PXF47774.1 - 0.17 11.2 0.0 0.64 9.3 0.0 1.9 1 1 0 2 2 2 0 Kinase-like RNA_pol_Rpb8 PF03870.15 PXF47776.1 - 5.1e-35 120.7 0.0 6.1e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 PXF47776.1 - 2e-08 34.3 1.3 9.6e-06 25.7 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G NTF2 PF02136.20 PXF47777.1 - 3.6e-29 101.8 0.0 4e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain WD40 PF00400.32 PXF47778.1 - 2e-05 25.2 7.9 1.3 10.0 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat KAR9 PF08580.10 PXF47778.1 - 2.9 6.3 8.1 5.3 5.5 8.1 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2344 PF10105.9 PXF47779.1 - 1e-40 139.5 0.0 1.7e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Radical_SAM PF04055.21 PXF47779.1 - 2.4e-13 50.8 0.0 3.9e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 Radical SAM superfamily B12-binding PF02310.19 PXF47779.1 - 0.044 13.8 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain BCIP PF13862.6 PXF47781.1 - 1.1e-30 107.0 0.1 5.2e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 p21-C-terminal region-binding protein Ten1_2 PF15490.6 PXF47781.1 - 0.033 13.9 0.0 0.28 10.9 0.0 2.4 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit YhcG_C PF06250.11 PXF47781.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain zf-RING_2 PF13639.6 PXF47782.1 - 4.8e-11 42.8 3.7 8.2e-11 42.1 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PXF47782.1 - 1.1e-07 32.0 2.9 2.7e-07 30.8 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PXF47782.1 - 1.3e-07 31.4 3.8 2.1e-07 30.7 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF47782.1 - 1.8e-06 27.7 2.6 2.8e-06 27.1 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF47782.1 - 5.4e-06 25.9 4.7 5.4e-06 25.9 4.7 1.9 2 1 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PXF47782.1 - 2.5e-05 24.0 2.6 3.9e-05 23.4 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF47782.1 - 3.1e-05 23.9 0.9 5.9e-05 23.0 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF47782.1 - 4.1e-05 23.5 2.3 6.4e-05 22.8 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF47782.1 - 6.7e-05 22.8 1.3 0.00022 21.2 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 PXF47782.1 - 0.00062 19.8 2.3 0.0019 18.3 2.3 1.9 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 PXF47782.1 - 0.0017 18.2 4.3 0.0027 17.5 4.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PXF47782.1 - 0.018 14.8 1.6 0.018 14.8 1.6 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-Nse PF11789.8 PXF47782.1 - 0.019 14.7 0.4 0.032 14.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 PXF47782.1 - 0.026 14.4 2.7 0.046 13.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 PXF47782.1 - 0.041 14.1 5.0 0.36 11.0 5.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 PXF47782.1 - 0.054 13.8 2.5 0.14 12.5 2.2 1.8 1 1 1 2 2 2 0 RING-like domain zf-C3H2C3 PF17122.5 PXF47782.1 - 0.19 11.8 4.6 0.69 10.0 4.6 1.9 1 1 0 1 1 1 0 Zinc-finger Siva PF05458.12 PXF47782.1 - 0.37 10.5 4.2 0.47 10.1 4.2 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-P11 PF03854.14 PXF47782.1 - 3.2 7.5 8.1 16 5.3 8.2 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_2 PF13639.6 PXF47783.1 - 7.5e-10 39.0 5.8 1.2e-09 38.3 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PXF47783.1 - 8.5e-09 35.6 3.9 1.7e-08 34.6 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 PXF47783.1 - 2.2e-08 33.6 2.7 3.7e-08 32.9 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 PXF47783.1 - 5.1e-08 32.7 4.4 7.8e-08 32.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF47783.1 - 1.4e-07 31.4 1.4 2.4e-07 30.7 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PXF47783.1 - 4.6e-07 29.6 5.9 4.6e-07 29.6 5.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF47783.1 - 2.3e-06 27.5 4.5 3e-06 27.2 1.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF47783.1 - 5.5e-06 26.2 2.5 8.7e-06 25.6 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF47783.1 - 1.3e-05 25.0 2.4 1.9e-05 24.4 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PXF47783.1 - 0.00046 20.3 6.0 0.0012 18.9 5.8 1.8 1 1 1 2 2 2 1 RING-variant domain zf-Nse PF11789.8 PXF47783.1 - 0.0055 16.5 2.4 0.0093 15.8 2.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 PXF47783.1 - 0.01 15.6 1.0 0.016 14.9 0.9 1.4 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PXF47783.1 - 0.012 15.5 9.6 0.023 14.6 2.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PXF47783.1 - 0.02 15.0 2.5 0.044 13.9 2.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CTU2 PF10288.9 PXF47783.1 - 0.033 14.4 0.7 3.7 7.8 0.1 2.1 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Rad50_zn_hook PF04423.14 PXF47783.1 - 0.038 13.8 3.2 0.68 9.8 0.4 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING-like PF08746.11 PXF47783.1 - 0.041 14.2 1.5 0.041 14.2 1.5 1.9 2 0 0 2 2 2 0 RING-like domain PHD PF00628.29 PXF47783.1 - 0.11 12.3 2.1 0.19 11.6 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 PXF47783.1 - 0.14 12.2 5.5 0.61 10.2 5.5 2.1 1 1 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 PXF47783.1 - 0.27 11.0 5.8 0.23 11.2 2.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 PXF47783.1 - 0.39 10.9 5.9 1.9 8.7 6.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 PXF47783.1 - 0.41 10.6 2.7 1.1 9.2 2.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 PXF47784.1 - 2.7e-10 40.4 5.0 4.2e-10 39.8 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 PXF47784.1 - 1.7e-08 33.9 3.8 3e-08 33.2 3.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PXF47784.1 - 1.1e-07 32.0 5.6 2.6e-07 30.8 5.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF47784.1 - 1.4e-07 31.2 5.6 2.6e-07 30.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF47784.1 - 2.4e-07 30.4 4.9 4.8e-07 29.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF47784.1 - 1.1e-05 25.2 4.2 1.7e-05 24.6 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF47784.1 - 1.9e-05 24.7 0.5 3e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF47784.1 - 7e-05 22.7 3.4 7e-05 22.7 3.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF47784.1 - 0.0001 22.2 1.5 0.00018 21.5 0.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 PXF47784.1 - 0.00066 19.8 7.0 0.0011 19.0 7.0 1.4 1 0 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 PXF47784.1 - 0.00078 19.2 4.1 0.0015 18.4 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PXF47784.1 - 0.014 15.2 1.0 0.027 14.3 1.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 PXF47784.1 - 0.025 14.3 1.8 0.025 14.3 1.8 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 PXF47784.1 - 0.045 13.8 2.6 0.1 12.7 2.6 1.6 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 PXF47784.1 - 0.048 13.5 4.1 0.077 12.9 4.1 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 PXF47784.1 - 0.05 13.9 4.0 0.11 12.9 4.0 1.6 1 1 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 PXF47784.1 - 0.17 11.7 0.8 0.27 11.1 0.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 PXF47784.1 - 0.17 12.1 6.1 0.78 10.0 6.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain His_Phos_1 PF00300.22 PXF47785.1 - 2.6e-41 141.5 0.0 1.7e-37 129.0 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) GST_N_3 PF13417.6 PXF47786.1 - 1.4e-14 54.3 0.0 5.9e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PXF47786.1 - 8e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF47786.1 - 2.2e-08 34.0 0.2 4.3e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PXF47786.1 - 2.4e-08 34.1 0.2 5e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PXF47786.1 - 4.9e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PXF47786.1 - 1.7e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PXF47786.1 - 0.034 14.7 0.0 0.056 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GFO_IDH_MocA PF01408.22 PXF47787.1 - 7.8e-27 94.5 0.0 1.6e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF47787.1 - 1.7e-12 47.4 0.0 1.9e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Rossmann-like PF10727.9 PXF47787.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.8 1 1 1 2 2 2 1 Rossmann-like domain 2-Hacid_dh_C PF02826.19 PXF47787.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 PXF47787.1 - 0.054 14.2 0.0 0.093 13.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DnaJ_CXXCXGXG PF00684.19 PXF47788.1 - 0.11 12.9 15.4 0.29 11.5 2.4 2.5 1 1 1 2 2 2 0 DnaJ central domain DUF1356 PF07092.12 PXF47788.1 - 4.6 6.4 5.5 12 5.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Anti-TRAP PF15777.5 PXF47788.1 - 9.3 6.3 11.5 2e+03 -1.2 11.6 2.8 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pex19 PF04614.12 PXF47789.1 - 4.6e-25 88.8 8.8 6.9e-25 88.2 8.8 1.3 1 1 0 1 1 1 1 Pex19 protein family NPA PF16469.5 PXF47789.1 - 0.017 15.7 0.7 0.043 14.4 0.7 1.9 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 CH PF00307.31 PXF47789.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain GCH_III PF05165.12 PXF47789.1 - 0.022 14.0 0.6 1.3 8.2 0.1 2.4 2 1 0 2 2 2 0 GTP cyclohydrolase III DUF5601 PF18151.1 PXF47789.1 - 0.039 14.3 0.2 6.9 7.1 0.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5601) pP_pnuc_1 PF18165.1 PXF47789.1 - 0.078 12.9 0.7 2.1 8.2 0.0 2.8 2 1 0 2 2 2 0 Predicted pPIWI-associating nuclease Tfb2 PF03849.14 PXF47789.1 - 0.14 11.1 0.1 0.18 10.8 0.1 1.3 1 1 0 1 1 1 0 Transcription factor Tfb2 CENP-I PF07778.11 PXF47789.1 - 0.17 10.5 0.3 0.25 10.0 0.3 1.1 1 0 0 1 1 1 0 Mis6 Spermine_synth PF01564.17 PXF47790.1 - 3.1e-69 232.2 0.0 4.4e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PXF47790.1 - 7.6e-20 70.6 0.1 1.3e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PXF47790.1 - 2.8e-05 24.7 0.0 6.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF47790.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 PXF47790.1 - 0.022 15.4 0.0 0.1 13.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 PXF47790.1 - 0.032 14.2 0.0 0.077 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 PXF47790.1 - 0.033 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 PXF47790.1 - 0.034 14.9 0.0 0.15 12.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 PXF47790.1 - 0.097 11.8 0.0 0.62 9.2 0.0 1.9 1 1 1 2 2 2 0 N2227-like protein Methyltransf_2 PF00891.18 PXF47790.1 - 0.14 11.5 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain YgbB PF02542.16 PXF47791.1 - 3e-61 206.2 0.1 4.6e-61 205.6 0.1 1.3 1 0 0 1 1 1 1 YgbB family PRA-PH PF01503.17 PXF47791.1 - 9.7e-18 64.4 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase IGPS PF00218.21 PXF47792.1 - 7.9e-22 77.6 0.0 9.3e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase DUF1771 PF08590.10 PXF47793.1 - 3.7e-16 59.2 13.9 5.9e-16 58.6 13.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 PXF47793.1 - 2.9e-11 43.5 0.3 8e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 Smr domain PAM2 PF07145.15 PXF47793.1 - 1.3e-05 24.6 0.7 1.3e-05 24.6 0.7 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region ApoLp-III PF07464.11 PXF47793.1 - 0.039 14.1 0.3 0.069 13.2 0.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PhoU PF01895.19 PXF47793.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoU domain AMPK1_CBM PF16561.5 PXF47794.1 - 1.8e-36 124.2 8.6 2e-18 66.4 0.5 2.8 3 0 0 3 3 3 2 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 PXF47794.1 - 0.015 15.8 8.1 1.1 9.9 1.4 3.2 3 0 0 3 3 3 0 Starch/carbohydrate-binding module (family 53) Cation_efflux PF01545.21 PXF47795.1 - 5.1e-50 170.0 0.5 6.7e-50 169.6 0.5 1.2 1 0 0 1 1 1 1 Cation efflux family Thioredox_DsbH PF03190.15 PXF47796.1 - 2.1e-53 180.6 0.0 4.7e-52 176.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PXF47796.1 - 2.8e-09 37.0 0.0 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 PXF47796.1 - 0.023 13.8 0.1 4.9 6.1 0.1 2.7 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 PXF47796.1 - 0.026 14.0 0.4 0.26 10.8 0.1 2.7 3 1 1 4 4 4 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 PXF47796.1 - 0.032 12.7 0.1 1 7.8 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 AsnC_trans_reg PF01037.21 PXF47796.1 - 0.048 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Sigma70_r4 PF04545.16 PXF47796.1 - 0.13 11.8 0.0 0.43 10.1 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 WD40 PF00400.32 PXF47797.1 - 2.3e-18 66.2 6.8 0.00013 22.7 0.3 7.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47797.1 - 5.1e-15 55.5 0.2 0.14 12.5 0.0 6.3 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF47797.1 - 8.5e-05 21.7 0.6 1.7 7.5 0.0 4.3 4 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF47797.1 - 0.00024 19.9 0.1 0.00077 18.2 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 PXF47797.1 - 0.15 12.1 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat RabGAP-TBC PF00566.18 PXF47798.1 - 4.5e-30 104.9 0.0 6.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PXF47799.1 - 1.6e-16 60.5 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47799.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF47799.1 - 9e-05 22.5 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF47799.1 - 0.0016 17.8 0.0 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF47799.1 - 0.006 16.2 0.1 0.0083 15.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Baculo_p47 PF05112.12 PXF47799.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein RIO1 PF01163.22 PXF47799.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 2 0 0 2 2 2 0 RIO1 family CDT1_C PF16679.5 PXF47800.1 - 0.057 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Uma2 PF05685.12 PXF47802.1 - 0.0021 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Kelch_5 PF13854.6 PXF47803.1 - 9.9e-34 114.8 0.1 2.8e-06 27.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PXF47803.1 - 6e-33 112.6 2.1 5.2e-07 29.6 0.0 7.1 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PXF47803.1 - 5.3e-29 99.9 0.0 8.8e-09 35.4 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PXF47803.1 - 1.8e-25 88.3 0.1 2.3e-05 24.5 0.0 6.5 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.25 PXF47803.1 - 5.8e-24 83.4 0.0 2.7e-05 23.7 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PXF47803.1 - 1.3e-20 72.5 1.6 0.0019 18.1 0.0 7.0 6 1 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 PXF47803.1 - 3.3e-16 59.2 7.3 3.3e-16 59.2 7.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) PNP_UDP_1 PF01048.20 PXF47804.1 - 2.6e-29 102.1 0.1 2.9e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-HIT PF04438.16 PXF47805.1 - 4.6e-08 32.8 14.2 7.9e-08 32.0 14.2 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 PXF47805.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 PXF47805.1 - 2 8.6 18.5 4.5 7.5 18.5 1.7 1 0 0 1 1 1 0 MYND finger Histone PF00125.24 PXF47806.1 - 7.5e-20 71.6 0.3 9e-20 71.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF47806.1 - 4.2e-06 26.9 0.1 8.3e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 PXF47806.1 - 0.017 15.2 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 YscO-like protein TFIID_20kDa PF03847.13 PXF47806.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone_H2A_C PF16211.5 PXF47807.1 - 2.6e-19 68.6 0.7 5.3e-19 67.7 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PXF47807.1 - 9.2e-17 61.6 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF47807.1 - 9.6e-05 22.6 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_3 PF01596.17 PXF47808.1 - 2.2e-42 144.6 0.0 2.5e-41 141.2 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase UPF0176_N PF17773.1 PXF47808.1 - 3.7e-19 68.9 0.0 1.5e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Methyltransf_24 PF13578.6 PXF47808.1 - 3.5e-11 44.1 0.4 2.8e-10 41.1 0.1 2.7 3 0 0 3 3 3 1 Methyltransferase domain Rhodanese_C PF12368.8 PXF47808.1 - 5.6e-10 39.4 10.3 1.6e-09 38.0 10.3 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 PXF47808.1 - 7.5e-07 29.6 0.0 2.7e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain PCMT PF01135.19 PXF47808.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PXF47808.1 - 0.02 15.6 0.1 0.093 13.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 PXF47808.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ATPase PF06745.13 PXF47808.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Nepo_coat_C PF03688.14 PXF47808.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, C-terminal domain RBFA PF02033.18 PXF47809.1 - 9e-20 71.1 0.2 1.3e-19 70.6 0.2 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A Tau95_N PF17682.1 PXF47809.1 - 0.16 12.2 0.5 0.32 11.2 0.2 1.7 1 1 1 2 2 2 0 Tau95 Triple barrel domain tRNA_anti-codon PF01336.25 PXF47811.1 - 2.7e-09 36.9 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 PXF47811.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Peptidase_C48 PF02902.19 PXF47813.1 - 4.7e-27 95.2 0.1 1.1e-26 94.1 0.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Transthyretin PF00576.21 PXF47814.1 - 1.5e-37 128.6 0.1 1.7e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 PXF47814.1 - 0.018 15.3 0.4 0.08 13.2 0.4 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_S41 PF03572.18 PXF47815.1 - 5.4e-38 130.2 0.0 8.5e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 PXF47815.1 - 3.7e-09 36.3 0.1 1.1e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PXF47815.1 - 1.4e-08 34.9 0.1 3.4e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PXF47815.1 - 8.5e-06 26.0 0.1 1.9e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 PXF47815.1 - 0.0062 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Tricorn_C1 PF14684.6 PXF47815.1 - 0.0089 16.1 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease C1 domain Uma2 PF05685.12 PXF47816.1 - 2.2e-28 98.9 0.0 2.9e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Mod_r PF07200.13 PXF47817.1 - 6.2e-18 65.3 14.9 8.1e-18 64.9 14.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 PXF47817.1 - 0.0016 17.4 9.9 0.0016 17.4 9.9 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein Mob_Pre PF01076.19 PXF47817.1 - 0.0041 17.0 3.9 0.0057 16.5 3.9 1.2 1 0 0 1 1 1 1 Plasmid recombination enzyme DUF2443 PF10398.9 PXF47817.1 - 0.022 14.8 1.6 1.9 8.6 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) SKA2 PF16740.5 PXF47817.1 - 0.029 14.2 3.7 0.07 12.9 3.7 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 PEP_mutase PF13714.6 PXF47817.1 - 0.11 11.9 0.9 0.18 11.2 0.9 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Fzo_mitofusin PF04799.13 PXF47817.1 - 0.58 9.7 6.7 0.49 9.9 4.5 2.0 1 1 1 2 2 2 0 fzo-like conserved region WD40_alt PF14077.6 PXF47817.1 - 0.83 9.6 3.7 0.85 9.5 2.2 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif MRP-S26 PF14943.6 PXF47817.1 - 2 8.3 10.0 1.4 8.8 8.7 1.4 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF445 PF04286.12 PXF47817.1 - 2.1 8.1 7.7 2.7 7.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COG2 PF06148.11 PXF47817.1 - 2.4 8.2 8.7 0.96 9.5 3.5 2.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.12 PXF47817.1 - 3.4 6.1 5.3 4.2 5.8 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 PXF47817.1 - 4.3 7.4 14.6 0.57 10.2 1.7 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding RTC PF01137.21 PXF47819.1 - 2.6e-42 144.5 0.0 3.1e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PXF47819.1 - 2.6e-25 88.9 0.0 5.4e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain zf-C2H2_jaz PF12171.8 PXF47820.1 - 3.9e-06 27.0 1.1 6.9e-06 26.2 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF47820.1 - 2.1e-05 24.7 1.3 3.5e-05 24.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PXF47820.1 - 0.014 15.7 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) YdjO PF14169.6 PXF47820.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO zf-C2H2_4 PF13894.6 PXF47820.1 - 0.12 13.2 1.2 0.22 12.5 0.6 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF47820.1 - 0.26 11.0 0.8 0.51 10.0 0.0 1.9 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Lipase_3 PF01764.25 PXF47821.1 - 2.9e-26 92.0 0.0 4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PXF47821.1 - 9.3e-06 26.4 0.1 1.4e-05 25.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PXF47821.1 - 0.0035 17.2 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF47821.1 - 0.0036 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PXF47821.1 - 0.005 16.6 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 PXF47821.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 PXF47821.1 - 0.014 15.6 0.1 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.8 PXF47821.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1180 PF06679.12 PXF47822.1 - 0.31 11.4 3.0 7 7.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sec10 PF07393.11 PXF47823.1 - 3.7e-06 25.7 0.0 1.3e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 Exocyst complex component Sec10 CREPT PF16566.5 PXF47823.1 - 0.036 14.2 2.3 0.089 13.0 0.5 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tyr-DNA_phospho PF06087.12 PXF47824.1 - 4.6e-84 282.8 0.0 5.8e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase SLATT_fungal PF18142.1 PXF47825.1 - 0.18 11.8 0.1 0.48 10.4 0.1 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Ribosomal_L32p PF01783.23 PXF47825.1 - 2.9 8.2 9.8 62 4.0 9.5 2.7 1 1 1 2 2 2 0 Ribosomal L32p protein family Peptidase_C14 PF00656.22 PXF47827.1 - 8.7e-17 61.9 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_S9_N PF02897.15 PXF47828.1 - 7.9e-111 370.8 2.7 1.1e-110 370.3 2.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PXF47828.1 - 3.8e-57 193.2 0.1 1e-56 191.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_C14 PF00656.22 PXF47829.1 - 9.1e-36 124.1 0.0 1.1e-35 123.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Transposase_21 PF02992.14 PXF47830.1 - 2.7e-15 56.2 0.6 3e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 PXF47830.1 - 0.064 12.9 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Lactamase_B PF00753.27 PXF47831.1 - 0.04 13.9 0.0 0.04 13.9 0.0 1.0 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AZUL PF16558.5 PXF47832.1 - 6.9 7.0 11.3 24 5.2 5.1 2.6 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A GMC_oxred_N PF00732.19 PXF47833.1 - 1.1e-36 126.7 0.0 2.9e-36 125.4 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PXF47833.1 - 4.9e-17 62.8 0.3 1.1e-16 61.6 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 PXF47833.1 - 0.00014 21.6 0.1 0.0035 17.0 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF47833.1 - 0.00023 20.3 0.1 0.0004 19.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 PXF47833.1 - 0.00034 20.8 0.1 0.0018 18.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PXF47833.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF47833.1 - 0.045 13.0 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 PXF47833.1 - 0.073 12.1 2.2 2.1 7.3 1.8 2.6 2 1 1 3 3 3 0 FAD binding domain ApbA PF02558.16 PXF47833.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 PXF47833.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PXF47833.1 - 0.16 11.2 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PXF47833.1 - 0.18 10.6 0.0 0.35 9.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase STAS_2 PF13466.6 PXF47835.1 - 0.77 10.1 23.1 55 4.2 0.2 7.5 1 1 7 8 8 8 0 STAS domain STAS_2 PF13466.6 PXF47837.1 - 0.0023 18.2 0.3 1.7e+02 2.6 0.0 5.6 2 2 6 8 8 8 1 STAS domain Dermcidin PF15291.6 PXF47838.1 - 0.34 11.5 0.6 17 6.0 0.1 2.2 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide Cornifin PF02389.15 PXF47840.1 - 4.1e-06 27.0 112.4 0.00038 20.7 27.7 4.8 2 1 3 5 5 5 4 Cornifin (SPRR) family PS_Dcarbxylase PF02666.15 PXF47845.1 - 1.4e-33 116.2 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase zf-C2H2_4 PF13894.6 PXF47846.1 - 1.5e-13 50.3 29.2 0.0022 18.7 0.2 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF47846.1 - 1.4e-12 47.3 32.5 3.3e-05 24.1 0.3 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-Di19 PF05605.12 PXF47846.1 - 4.7e-09 36.4 21.3 2.9e-07 30.7 3.5 3.4 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 PXF47846.1 - 2.1e-06 27.8 12.0 0.16 12.3 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 PXF47846.1 - 4.4e-05 23.4 7.6 0.055 13.5 0.6 3.1 1 1 2 3 3 3 2 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 PXF47846.1 - 0.00011 22.5 21.6 0.57 10.7 0.5 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 PXF47846.1 - 0.0002 21.6 15.1 1.8 9.1 0.1 5.4 6 0 0 6 6 5 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 PXF47846.1 - 0.0014 18.3 17.9 3.3 7.4 0.4 5.2 1 1 4 5 5 5 1 Zinc-fingers and homeoboxes C2H2 finger domain C1_2 PF03107.16 PXF47846.1 - 0.034 14.5 10.2 0.79 10.1 0.3 4.5 5 0 0 5 5 4 0 C1 domain zf_Hakai PF18408.1 PXF47846.1 - 0.035 13.8 8.3 0.45 10.3 0.1 2.9 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain PIH1 PF08190.12 PXF47846.1 - 0.036 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 PIH1 N-terminal domain DUF2256 PF10013.9 PXF47846.1 - 0.067 13.3 8.1 17 5.6 0.0 4.8 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYST PF17772.1 PXF47846.1 - 0.12 12.0 14.2 2.5 7.8 0.3 4.0 2 2 2 4 4 4 0 MYST family zinc finger domain TF_Zn_Ribbon PF08271.12 PXF47846.1 - 0.13 11.8 7.7 1.4 8.5 0.8 3.5 2 1 0 3 3 3 0 TFIIB zinc-binding zf-C2HC_2 PF13913.6 PXF47846.1 - 0.14 12.0 10.6 5.4 7.0 0.1 4.4 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 PXF47846.1 - 0.25 12.0 8.3 0.16 12.7 0.8 3.2 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats PhnA_Zn_Ribbon PF08274.12 PXF47846.1 - 0.26 11.3 11.0 8.4 6.4 0.8 4.1 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zf_C2H2_10 PF18414.1 PXF47846.1 - 0.46 10.1 4.1 6.5 6.4 0.8 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger PyrI_C PF02748.15 PXF47846.1 - 0.63 10.0 0.1 0.63 10.0 0.1 2.7 4 1 1 5 5 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.16 PXF47846.1 - 0.71 10.1 7.5 47 4.3 0.1 4.2 4 0 0 4 4 4 0 AN1-like Zinc finger Actin_micro PF17003.5 PXF47846.1 - 1.8 7.7 13.0 3.6 6.7 0.2 3.9 1 1 2 3 3 3 0 Putative actin-like family zf-BED PF02892.15 PXF47846.1 - 2 8.5 16.0 2.8 8.0 0.3 3.7 2 2 1 3 3 3 0 BED zinc finger A2L_zn_ribbon PF08792.10 PXF47846.1 - 2.9 7.7 6.7 3.1 7.6 0.2 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-C2H2_9 PF16293.5 PXF47846.1 - 3.3 7.6 7.7 18 5.3 0.1 3.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Mut7-C PF01927.16 PXF47846.1 - 3.7 7.6 9.8 6.5 6.9 0.5 3.1 2 1 0 3 3 3 0 Mut7-C RNAse domain zf-Mss51 PF13824.6 PXF47846.1 - 5.1 7.3 11.3 8.4 6.6 1.4 3.1 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 CpXC PF14353.6 PXF47846.1 - 5.6 7.0 12.2 35 4.5 0.1 4.0 1 1 2 3 3 3 0 CpXC protein Gpr1_Fun34_YaaH PF01184.19 PXF47848.1 - 2e-20 73.3 10.1 2.6e-20 72.9 10.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-C2H2 PF00096.26 PXF47849.1 - 3.8e-15 55.4 38.3 0.0012 19.1 3.0 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF47849.1 - 5.7e-14 51.6 36.0 0.0012 19.5 1.7 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF47849.1 - 7e-07 29.4 20.9 0.1 12.9 0.0 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF47849.1 - 1.4e-06 28.5 18.2 0.0085 16.5 0.1 6.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 PXF47849.1 - 0.00014 22.1 2.0 0.00014 22.1 2.0 4.2 1 1 2 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 PXF47849.1 - 0.00017 21.5 33.0 0.012 15.6 0.2 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 PXF47849.1 - 0.00093 19.0 28.4 0.74 9.8 0.1 6.0 6 1 0 6 6 6 4 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 PXF47849.1 - 0.005 17.5 0.3 0.005 17.5 0.3 3.4 4 0 0 4 4 4 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 PXF47849.1 - 0.041 14.3 29.9 0.65 10.5 0.5 6.6 6 0 0 6 6 6 0 Zinc-finger double domain zf_UBZ PF18439.1 PXF47849.1 - 0.72 9.5 7.3 14 5.4 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf_Hakai PF18408.1 PXF47849.1 - 4.3 7.1 14.4 7.4 6.4 0.8 4.3 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain Desulfoferrod_N PF06397.12 PXF47849.1 - 5.3 6.8 7.0 1.2 8.8 0.2 2.7 3 0 0 3 3 2 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_4 PF13894.6 PXF47850.1 - 5.6e-15 54.8 36.8 0.0023 18.6 0.4 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF47850.1 - 1.4e-14 53.6 41.5 0.017 15.5 0.4 6.5 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PXF47850.1 - 8.1e-07 29.2 23.1 0.11 12.8 0.0 6.2 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF47850.1 - 1.9e-05 24.9 24.7 0.011 16.1 0.1 5.7 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 PXF47850.1 - 0.0097 15.8 29.1 1 9.3 0.5 6.1 5 2 0 5 5 5 4 zinc-finger of a C2HC-type Elf1 PF05129.13 PXF47850.1 - 0.012 15.6 20.2 0.02 14.9 8.1 3.5 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.6 PXF47850.1 - 0.057 13.4 0.3 0.057 13.4 0.3 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF47850.1 - 0.1 13.3 0.4 0.1 13.3 0.4 3.8 3 1 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 PXF47850.1 - 0.15 11.9 33.0 0.74 9.6 0.6 5.1 6 0 0 6 6 6 0 zinc-finger C2H2-type zf_Hakai PF18408.1 PXF47850.1 - 0.78 9.5 20.2 24 4.7 2.9 4.6 4 0 0 4 4 4 0 C2H2 Hakai zinc finger domain RNA_pol_Rpb2_6 PF00562.28 PXF47851.1 - 1.9e-125 419.0 0.0 2.9e-125 418.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PXF47851.1 - 5.6e-56 189.3 0.0 7.9e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 PXF47851.1 - 5e-35 120.9 0.0 1.6e-34 119.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 PXF47851.1 - 1.4e-32 111.9 0.2 3.5e-32 110.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 PXF47851.1 - 2.2e-26 91.8 0.0 5.4e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PXF47851.1 - 2.6e-26 91.7 0.2 8.4e-26 90.1 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 PXF47851.1 - 1.7e-15 57.3 1.4 4.8e-15 55.9 1.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RecR PF02132.15 PXF47851.1 - 3.3 7.4 8.6 0.68 9.6 0.7 3.0 2 1 1 3 3 3 0 RecR protein CN_hydrolase PF00795.22 PXF47853.1 - 3e-50 171.0 0.0 4.1e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase YEATS PF03366.16 PXF47854.1 - 2.7e-29 100.9 1.5 5.2e-29 100.1 1.5 1.5 1 0 0 1 1 1 1 YEATS family Synaphin PF05835.12 PXF47854.1 - 0.18 12.1 4.3 0.15 12.4 2.8 1.5 2 0 0 2 2 2 0 Synaphin protein Lgl_C PF08596.10 PXF47855.1 - 0.23 10.1 1.8 0.6 8.7 0.3 2.1 2 1 1 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal RRM_1 PF00076.22 PXF47856.1 - 2e-05 24.3 0.0 4.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMU163 PF17119.5 PXF47856.1 - 0.034 13.3 1.1 0.052 12.7 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Nre_C PF04895.12 PXF47856.1 - 0.49 10.3 2.2 0.45 10.4 0.7 1.8 2 0 0 2 2 2 0 Archaeal Nre, C-terminal MbeB_N PF04837.12 PXF47856.1 - 4.7 7.6 5.9 3.3 8.1 2.7 2.4 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DUF563 PF04577.14 PXF47857.1 - 5.5e-18 65.9 0.1 1.4e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF726 PF05277.12 PXF47858.1 - 4.3e-65 219.9 12.4 3.2e-52 177.6 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF726) DUF3089 PF11288.8 PXF47858.1 - 0.011 15.4 0.0 0.083 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) DHquinase_I PF01487.15 PXF47859.1 - 1.8e-52 178.9 0.0 2.8e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 PXF47859.1 - 4.9e-24 84.4 0.0 1.8e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 PXF47859.1 - 2.1e-11 43.4 0.3 3.6e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 PXF47859.1 - 5.4e-09 36.2 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PXF47859.1 - 1.8e-05 25.3 0.7 5.1e-05 23.8 0.1 2.1 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PXF47859.1 - 0.00084 19.6 0.1 0.0021 18.3 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 PXF47859.1 - 0.0087 15.2 1.0 0.013 14.6 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.25 PXF47859.1 - 0.018 14.5 0.1 0.042 13.3 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase PALP PF00291.25 PXF47859.1 - 0.03 13.7 0.1 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF3783 PF12646.7 PXF47859.1 - 0.039 13.9 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) DeoC PF01791.9 PXF47859.1 - 0.062 12.9 0.0 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 DeoC/LacD family aldolase tRNA-synt_2c PF01411.19 PXF47861.1 - 2.8e-204 679.7 0.0 3.6e-204 679.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PXF47861.1 - 7.9e-15 54.7 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 PXF47861.1 - 3.7e-10 40.4 0.3 8.5e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 DHHA1 domain Pox_A8 PF04745.12 PXF47861.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 VITF-3 subunit protein SpoU_methylase PF00588.19 PXF47862.1 - 1.3e-28 100.0 0.0 1.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 PXF47862.1 - 4.2e-07 30.1 0.0 8.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding HEM4 PF02602.15 PXF47863.1 - 3e-44 151.1 0.1 1.7e-43 148.7 0.1 1.8 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD PsbM PF05151.12 PXF47865.1 - 1.2e-06 28.2 2.4 1.2e-06 28.2 2.4 1.8 2 0 0 2 2 2 1 Photosystem II reaction centre M protein (PsbM) AAA_33 PF13671.6 PXF47866.1 - 3.7e-14 53.1 0.1 5.4e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PXF47866.1 - 1.2e-05 25.9 0.1 2.9e-05 24.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 PXF47866.1 - 8.5e-05 22.7 0.1 0.0027 17.9 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.6 PXF47866.1 - 0.00063 20.2 0.0 0.001 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 PXF47866.1 - 0.00072 19.1 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 PXF47866.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 PXF47866.1 - 0.0026 17.4 0.1 0.01 15.5 0.0 1.9 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Hydin_ADK PF17213.3 PXF47866.1 - 0.0027 18.0 0.6 0.017 15.4 0.1 1.9 1 1 0 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 PXF47866.1 - 0.0057 16.0 0.1 0.0099 15.2 0.1 1.7 1 1 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 PXF47866.1 - 0.006 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PXF47866.1 - 0.0072 16.4 0.0 0.033 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 PXF47866.1 - 0.0092 15.9 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.6 PXF47866.1 - 0.0099 16.3 0.2 0.06 13.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PXF47866.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 PXF47866.1 - 0.018 15.2 0.2 0.074 13.2 0.1 2.0 1 1 1 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 PXF47866.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 PXF47866.1 - 0.024 13.7 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 PXF47866.1 - 0.028 13.6 0.0 0.067 12.4 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_25 PF13481.6 PXF47866.1 - 0.04 13.5 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PXF47866.1 - 0.04 14.3 0.0 0.18 12.2 0.0 2.1 2 1 0 2 2 2 0 RNA helicase Hpr_kinase_C PF07475.12 PXF47866.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_30 PF13604.6 PXF47866.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF47866.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 PXF47866.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 PXF47866.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PXF47866.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PXF47866.1 - 0.19 11.8 0.0 0.7 10.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase TPR_2 PF07719.17 PXF47867.1 - 1.6e-37 124.6 16.5 1.1e-05 25.2 0.0 12.9 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 PXF47867.1 - 1.5e-30 103.2 30.7 8.2e-05 23.1 0.3 12.9 1 1 12 13 13 13 10 Tetratricopeptide repeat TPR_17 PF13431.6 PXF47867.1 - 7.4e-29 98.0 4.3 0.013 15.9 0.0 9.9 11 0 0 11 11 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 PXF47867.1 - 2e-26 89.9 0.4 0.0015 18.6 0.0 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 PXF47867.1 - 3.8e-24 85.0 0.5 0.01 16.3 0.0 7.8 5 2 4 9 9 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 PXF47867.1 - 2.1e-22 77.9 0.1 0.0027 17.4 0.0 10.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 PXF47867.1 - 1.3e-21 76.0 0.0 0.012 15.3 0.1 9.2 6 2 4 10 10 10 4 TPR repeat TPR_12 PF13424.6 PXF47867.1 - 9.1e-19 67.5 21.8 6.1e-05 23.2 1.4 7.8 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 PXF47867.1 - 1.8e-16 60.5 18.2 0.0021 18.6 0.3 8.2 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_15 PF13429.6 PXF47867.1 - 3.8e-14 52.6 19.6 0.00074 18.8 0.0 4.7 2 2 1 4 4 4 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF47867.1 - 3.9e-12 46.2 6.0 0.053 13.5 0.3 7.0 5 2 0 5 5 4 4 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 PXF47867.1 - 9.9e-12 44.8 17.9 5.6e-05 23.2 0.1 6.6 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 PXF47867.1 - 1.4e-09 38.0 19.7 0.0017 18.8 0.1 9.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF47867.1 - 1.5e-07 30.9 11.9 2.2 8.5 0.1 8.2 10 0 0 10 10 8 3 Tetratricopeptide repeat MIT PF04212.18 PXF47867.1 - 7.2e-07 29.2 3.0 1 9.5 0.0 6.7 8 0 0 8 8 7 1 MIT (microtubule interacting and transport) domain Suf PF05843.14 PXF47867.1 - 3.7e-06 27.2 0.8 3 7.8 0.0 4.6 3 2 1 4 4 4 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 PXF47867.1 - 4.6e-05 22.7 3.5 0.0082 15.3 0.0 2.5 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_10 PF13374.6 PXF47867.1 - 0.0019 18.0 15.4 0.86 9.6 0.1 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat NARP1 PF12569.8 PXF47867.1 - 0.0064 15.5 0.4 0.68 8.8 0.0 3.3 1 1 2 4 4 4 1 NMDA receptor-regulated protein 1 Sel1 PF08238.12 PXF47867.1 - 0.012 16.3 13.5 46 4.9 0.0 7.8 8 1 2 10 10 9 0 Sel1 repeat DUF4192 PF13830.6 PXF47867.1 - 0.018 15.1 13.1 0.055 13.5 0.1 4.3 3 2 0 4 4 4 0 Domain of unknown function (DUF4192) DUF4817 PF16087.5 PXF47867.1 - 0.16 11.8 0.3 0.78 9.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) TAtT PF16811.5 PXF47867.1 - 0.36 10.1 4.1 17 4.6 0.0 4.6 5 1 1 6 6 6 0 TRAP transporter T-component HemY_N PF07219.13 PXF47867.1 - 0.45 10.7 4.3 19 5.5 0.0 5.1 4 1 3 7 7 6 0 HemY protein N-terminus HAT PF02184.16 PXF47867.1 - 0.75 9.8 0.0 0.75 9.8 0.0 5.1 6 0 0 6 6 5 0 HAT (Half-A-TPR) repeat TPR_4 PF07721.14 PXF47867.1 - 8.1 7.4 17.2 1.8 9.4 0.7 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 PXF47868.1 - 2.8e-276 918.7 0.5 1.1e-274 913.4 0.5 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family TssN PF17555.2 PXF47868.1 - 1.7 8.0 9.3 0.61 9.4 3.0 2.5 2 1 0 2 2 2 0 Type VI secretion system, TssN VPS13_C PF16909.5 PXF47869.1 - 3.2e-38 131.3 0.7 1.5e-34 119.3 0.0 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PXF47869.1 - 3.3e-32 112.2 0.0 9.3e-31 107.4 0.0 2.9 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PXF47869.1 - 1.8e-26 92.5 0.0 5.2e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 PXF47869.1 - 3.5e-19 69.2 0.0 3.4e-18 66.0 0.0 2.6 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 PXF47869.1 - 5.1e-12 45.7 1.2 3.3e-10 39.8 0.0 3.6 4 0 0 4 4 4 1 Repeating coiled region of VPS13 ATG_C PF09333.11 PXF47869.1 - 0.00057 20.2 0.0 0.0022 18.3 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UBA PF00627.31 PXF47869.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain RuvA_C PF07499.13 PXF47869.1 - 0.14 12.7 0.0 0.5 10.9 0.0 1.9 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF647 PF04884.14 PXF47870.1 - 3e-68 230.0 0.3 4.4e-68 229.5 0.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MMtag PF10159.9 PXF47872.1 - 1.8e-12 47.3 0.0 1.8e-12 47.3 0.0 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated RR_TM4-6 PF06459.12 PXF47872.1 - 1.5 8.6 5.0 2 8.2 5.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XRN_M PF17846.1 PXF47872.1 - 3.7 6.4 6.4 4.4 6.1 6.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Mpv17_PMP22 PF04117.12 PXF47874.1 - 5e-25 87.5 1.5 1.1e-24 86.5 1.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family 4HBT_3 PF13622.6 PXF47874.1 - 0.078 13.2 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily ORC2 PF04084.14 PXF47875.1 - 6.9e-76 255.3 0.0 8.3e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Glycos_transf_4 PF00953.21 PXF47877.1 - 2.7e-35 121.7 12.2 2.7e-35 121.7 12.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 Arf PF00025.21 PXF47878.1 - 1.8e-41 141.5 0.0 6.9e-41 139.6 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PXF47878.1 - 9.7e-14 51.3 0.0 9.3e-10 38.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PXF47878.1 - 2.1e-08 34.4 0.0 4e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF47878.1 - 8.8e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 PXF47878.1 - 4e-05 23.1 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PXF47878.1 - 0.00019 21.5 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PXF47878.1 - 0.00044 19.7 0.0 0.00096 18.6 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 PXF47878.1 - 0.14 12.2 0.0 10 6.2 0.1 2.2 2 0 0 2 2 2 0 Dynamin family EMP70 PF02990.16 PXF47879.1 - 1.5e-184 614.5 0.6 1.5e-184 614.5 0.6 1.6 1 1 1 2 2 2 1 Endomembrane protein 70 DmpG_comm PF07836.11 PXF47879.1 - 0.52 9.9 1.9 2.1 7.9 0.3 2.3 2 0 0 2 2 2 0 DmpG-like communication domain BRK PF07533.16 PXF47880.1 - 1.2e-15 56.9 0.2 6.4e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 BRK domain Img2 PF05046.14 PXF47880.1 - 0.026 14.8 0.0 11 6.4 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) zf-UBP PF02148.19 PXF47881.1 - 5e-16 58.8 6.9 7.4e-16 58.2 6.9 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_S19 PF00203.21 PXF47882.1 - 1.1e-33 114.9 1.0 1.5e-33 114.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF5055 PF16478.5 PXF47882.1 - 0.025 14.8 0.7 0.17 12.2 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5055) Ufm1 PF03671.14 PXF47883.1 - 3.8e-43 145.4 0.2 4.3e-43 145.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein DUF2997 PF11211.8 PXF47885.1 - 4.7e-17 61.5 2.9 6.8e-17 61.0 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) YwqJ-deaminase PF14431.6 PXF47885.1 - 0.11 12.7 0.1 1.1 9.5 0.2 2.0 1 1 1 2 2 2 0 YwqJ-like deaminase UCR_14kD PF02271.16 PXF47886.1 - 1.3e-23 82.8 2.0 1.5e-23 82.7 2.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF2293 PF10056.9 PXF47886.1 - 0.027 14.7 0.1 0.041 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) DUF4041 PF13250.6 PXF47886.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) NifU PF01106.17 PXF47887.1 - 1.2e-24 86.2 4.3 2.5e-18 66.0 0.3 3.7 3 1 0 3 3 3 2 NifU-like domain GIY-YIG PF01541.24 PXF47887.1 - 0.035 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain Flavokinase PF01687.17 PXF47887.1 - 0.15 12.4 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Riboflavin kinase GRIM-19 PF06212.12 PXF47887.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein MRP-S34 PF16053.5 PXF47888.1 - 1.7e-10 40.6 0.9 2.3e-10 40.2 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 adh_short_C2 PF13561.6 PXF47889.1 - 1.7e-79 266.6 0.1 2.1e-79 266.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PXF47889.1 - 1.4e-19 70.4 0.0 1.8e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 PXF47889.1 - 0.0021 17.5 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 Trans-2-enoyl-CoA reductase catalytic region IF-2B PF01008.17 PXF47890.1 - 5.5e-13 48.8 0.3 7.2e-13 48.4 0.3 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Y_phosphatase PF00102.27 PXF47891.1 - 0.0031 17.1 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PXF47891.1 - 0.0044 16.8 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SIS PF01380.22 PXF47891.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SIS domain O-FucT PF10250.9 PXF47892.1 - 1.1e-07 31.8 0.0 3.5e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4962 PF16332.5 PXF47892.1 - 0.09 11.3 0.3 0.14 10.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) RMF PF04957.12 PXF47893.1 - 0.12 12.6 0.2 19 5.6 0.1 2.5 2 0 0 2 2 2 0 Ribosome modulation factor DUF5527 PF17665.1 PXF47893.1 - 0.15 11.6 0.3 0.58 9.7 0.0 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5527) MADF_DNA_bdg PF10545.9 PXF47893.1 - 0.29 11.5 0.1 0.29 11.5 0.1 2.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EI24 PF07264.11 PXF47894.1 - 5e-07 30.1 0.0 9.4e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) GrpE PF01025.19 PXF47895.1 - 7.2e-45 152.6 0.0 9.3e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 GrpE Sigma54_DBD PF04552.13 PXF47895.1 - 0.056 13.1 0.5 0.089 12.5 0.5 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain ThiS PF02597.20 PXF47895.1 - 0.078 13.6 0.3 0.17 12.5 0.3 1.6 1 0 0 1 1 1 0 ThiS family TTRAP PF14203.6 PXF47895.1 - 0.15 12.1 1.1 0.28 11.2 1.1 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Malectin PF11721.8 PXF47896.1 - 7.3e-14 52.2 0.0 0.0038 17.3 0.0 3.7 3 0 0 3 3 3 3 Malectin domain GTP_EFTU PF00009.27 PXF47898.1 - 1.4e-33 116.1 3.1 1.5e-33 116.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PXF47898.1 - 4.1e-21 75.1 1.0 8.9e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 PXF47898.1 - 1.3e-15 57.1 1.9 1.5e-15 56.9 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 PXF47898.1 - 3.3e-11 43.4 10.8 2.7e-08 34.1 0.8 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF47898.1 - 1.3e-07 31.7 2.2 5.4e-07 29.7 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 PXF47898.1 - 0.0003 21.0 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 PXF47898.1 - 0.076 12.8 0.0 0.27 11.0 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 PXF47899.1 - 3.1e-38 131.6 29.1 3.1e-38 131.6 29.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PXF47899.1 - 3.3e-11 42.7 5.7 3.3e-11 42.7 5.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 PXF47899.1 - 2.4e-06 26.1 14.5 0.012 13.9 0.5 4.1 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family RibD_C PF01872.17 PXF47900.1 - 3e-37 128.4 0.0 3.5e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Ald_Xan_dh_C2 PF02738.18 PXF47901.1 - 9.9e-180 598.6 0.0 1.3e-179 598.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PXF47901.1 - 1.5e-44 151.7 0.0 3.3e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 PXF47901.1 - 3.5e-29 101.4 0.2 1.1e-28 99.7 0.1 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PXF47901.1 - 1.7e-25 88.9 0.0 4.9e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PXF47901.1 - 5.8e-23 81.0 0.0 1.7e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PXF47901.1 - 9.5e-07 28.7 1.0 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SelP_C PF04593.14 PXF47901.1 - 0.072 13.1 1.9 0.17 11.9 0.8 2.1 3 0 0 3 3 3 0 Selenoprotein P, C terminal region Hyphal_reg_CWP PF11765.8 PXF47901.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal VID27 PF08553.10 PXF47902.1 - 2.7e-109 365.5 0.2 3.8e-109 365.0 0.2 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 PXF47902.1 - 4.7e-08 33.3 0.2 8.2e-07 29.3 0.1 3.0 4 0 0 4 4 4 1 VID27 PH-like domain DUF4810 PF16068.5 PXF47903.1 - 0.13 12.8 5.1 2.5 8.7 0.3 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) HBS1_N PF08938.10 PXF47903.1 - 1.6 9.1 6.5 3.3 8.1 3.3 3.3 3 0 0 3 3 3 0 HBS1 N-terminus DUF3854 PF12965.7 PXF47903.1 - 5.9 6.9 5.3 18 5.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) Cpn10 PF00166.21 PXF47904.1 - 8.5e-28 96.3 0.0 9.4e-28 96.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit LSM PF01423.22 PXF47905.1 - 5.4e-16 58.0 0.4 6.6e-16 57.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain RF-1 PF00472.20 PXF47907.1 - 4.4e-25 87.9 2.8 5.8e-25 87.5 2.8 1.1 1 0 0 1 1 1 1 RF-1 domain Mito_carr PF00153.27 PXF47908.1 - 6.7e-63 208.7 1.4 1.3e-23 82.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Oxysterol_BP PF01237.18 PXF47909.1 - 1.6e-67 227.9 0.0 3.6e-65 220.2 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein HrpB7 PF09486.10 PXF47910.1 - 0.023 15.1 8.8 0.074 13.4 0.2 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 PXF47910.1 - 0.11 12.6 10.5 0.56 10.3 2.1 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF3824 PF12868.7 PXF47910.1 - 0.43 11.2 5.7 1.7 9.3 5.7 2.0 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Laminin_II PF06009.12 PXF47910.1 - 0.92 9.5 7.0 0.18 11.8 0.4 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF4200 PF13863.6 PXF47910.1 - 1.4 9.3 10.1 3.1 8.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GrpE PF01025.19 PXF47910.1 - 2.1 8.0 9.9 0.29 10.8 1.0 2.2 2 0 0 2 2 2 0 GrpE Prefoldin_2 PF01920.20 PXF47910.1 - 3 7.9 11.2 2.7 8.0 2.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 PXF47910.1 - 4.6 5.7 5.0 3.1 6.3 0.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A MFS_1 PF07690.16 PXF47911.1 - 8e-27 94.1 32.0 8e-27 94.1 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M28 PF04389.17 PXF47912.1 - 3.5e-36 124.8 0.0 5.7e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 PXF47912.1 - 3.6e-05 23.6 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 FAD_binding_7 PF03441.14 PXF47913.1 - 1.4e-55 187.9 0.5 2.6e-55 187.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PXF47913.1 - 1.9e-20 73.5 0.2 5.2e-20 72.1 0.2 1.7 1 0 0 1 1 1 1 DNA photolyase OHCU_decarbox PF09349.10 PXF47914.1 - 6.5e-36 124.2 2.8 1.5e-35 123.0 2.8 1.6 1 0 0 1 1 1 1 OHCU decarboxylase ARGLU PF15346.6 PXF47914.1 - 0.0035 17.2 3.1 0.044 13.7 2.4 2.3 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 Polysacc_deac_1 PF01522.21 PXF47914.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase FRG1 PF06229.12 PXF47915.1 - 1.2 8.8 7.5 0.54 9.9 5.0 1.6 1 1 0 1 1 1 0 FRG1-like domain Rsm22 PF09243.10 PXF47916.1 - 5.8e-42 143.9 0.0 4.8e-26 91.6 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 PXF47916.1 - 6.6e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF47916.1 - 0.012 16.3 0.0 0.04 14.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 PXF47916.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PXF47916.1 - 0.18 12.6 0.0 0.5 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain eIF-5_eIF-2B PF01873.17 PXF47917.1 - 5.5e-35 119.8 0.0 1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PseudoU_synth_1 PF01416.20 PXF47918.1 - 1e-09 38.8 0.1 4e-06 27.2 0.1 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase BPL_LplA_LipB PF03099.19 PXF47920.1 - 5.5e-08 32.8 0.0 2.2e-07 30.8 0.0 2.0 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Sipho_Gp157 PF05565.11 PXF47920.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 Glycos_transf_3 PF00591.21 PXF47921.1 - 6.1e-83 278.3 0.5 8.4e-83 277.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 PXF47921.1 - 1.7e-14 53.4 0.1 6e-14 51.6 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain ACC_epsilon PF13822.6 PXF47921.1 - 0.72 10.6 3.2 0.33 11.7 0.7 1.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit TTKRSYEDQ PF10212.9 PXF47922.1 - 0.0072 15.4 11.2 0.0072 15.4 11.2 2.6 2 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein DUF948 PF06103.11 PXF47922.1 - 0.011 16.0 2.5 0.011 16.0 2.5 3.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) MCC-bdg_PDZ PF10506.9 PXF47922.1 - 0.031 14.3 4.6 0.098 12.7 1.0 2.9 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4392 PF14336.6 PXF47922.1 - 0.73 9.2 6.3 0.68 9.3 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4392) Cep57_CLD_2 PF14197.6 PXF47922.1 - 1.7 8.8 24.9 0.084 13.0 5.5 4.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Tweety PF04906.13 PXF47922.1 - 2.6 6.6 4.1 4.6 5.8 4.1 1.4 1 0 0 1 1 1 0 Tweety NUC PF18510.1 PXF47922.1 - 9.4 6.6 11.9 0.58 10.6 0.9 3.0 2 1 1 3 3 3 0 Nuclease domain BPL_LplA_LipB PF03099.19 PXF47923.1 - 9.8e-16 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.25 PXF47924.1 - 3.4e-17 62.7 0.0 4.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47924.1 - 3.6e-08 33.0 0.0 4.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC_membrane PF00664.23 PXF47926.1 - 9.3e-108 360.0 21.9 7.7e-59 199.6 8.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF47926.1 - 2.4e-67 225.7 0.1 5.1e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PXF47926.1 - 4e-14 52.6 0.6 9.2e-07 28.5 0.0 4.0 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PXF47926.1 - 1.7e-08 33.7 1.2 0.0023 16.8 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 PXF47926.1 - 2.3e-06 27.6 0.2 0.011 15.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PXF47926.1 - 2.6e-05 23.9 1.9 0.092 12.5 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF47926.1 - 3.6e-05 24.1 4.3 0.2 11.9 0.1 4.5 3 3 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 PXF47926.1 - 0.00016 21.7 1.1 0.13 12.1 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 PXF47926.1 - 0.00027 21.4 0.7 0.41 11.0 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 PXF47926.1 - 0.0004 19.7 0.1 0.057 12.7 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 PXF47926.1 - 0.0011 19.5 0.0 0.62 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 PXF47926.1 - 0.0013 18.7 0.1 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF87 PF01935.17 PXF47926.1 - 0.0027 17.8 0.1 1.2 9.2 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain G-alpha PF00503.20 PXF47926.1 - 0.0064 15.7 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_30 PF13604.6 PXF47926.1 - 0.0069 16.1 0.2 2 8.1 0.0 3.2 2 2 0 2 2 2 1 AAA domain PRK PF00485.18 PXF47926.1 - 0.022 14.5 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Tex_YqgF PF16921.5 PXF47926.1 - 0.024 15.1 0.9 12 6.4 0.1 2.9 3 0 0 3 3 2 0 Tex protein YqgF-like domain AAA_33 PF13671.6 PXF47926.1 - 0.026 14.7 0.0 0.57 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain SUR7 PF06687.12 PXF47926.1 - 0.039 13.6 1.3 0.12 12.0 1.3 1.9 1 0 0 1 1 1 0 SUR7/PalI family AAA_10 PF12846.7 PXF47926.1 - 0.054 12.4 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.6 PXF47926.1 - 0.062 13.0 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 PXF47926.1 - 0.075 13.3 2.0 17 5.7 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 PXF47926.1 - 0.082 13.3 0.2 44 4.5 0.1 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2207 PF09972.9 PXF47926.1 - 0.087 11.6 0.0 0.087 11.6 0.0 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) RNA_helicase PF00910.22 PXF47926.1 - 0.17 12.3 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 PXF47926.1 - 0.18 11.5 1.6 18 5.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system HlyIII PF03006.20 PXF47926.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.6 4 0 0 4 4 4 0 Haemolysin-III related DUF2417 PF10329.9 PXF47926.1 - 0.21 11.0 5.7 0.34 10.3 0.4 3.3 4 0 0 4 4 4 0 Region of unknown function (DUF2417) NB-ARC PF00931.22 PXF47926.1 - 0.23 10.6 0.2 13 4.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 PXF47926.1 - 0.37 11.3 4.4 6 7.3 0.2 2.6 3 0 0 3 3 2 0 AAA domain HTH_9 PF08221.11 PXF47927.1 - 3.4e-11 43.1 1.0 0.019 15.0 0.0 4.5 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 PXF47927.1 - 0.00059 19.7 0.0 0.0024 17.7 0.1 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit RNase_H PF00075.24 PXF47928.1 - 2.6e-38 131.4 0.0 4.4e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 PXF47928.1 - 2.8e-16 59.5 0.4 6.4e-16 58.4 0.4 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin MAGE_N PF12440.8 PXF47928.1 - 0.072 13.8 0.9 0.12 13.1 0.9 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Cwf_Cwc_15 PF04889.12 PXF47929.1 - 5.8e-50 170.3 22.7 7.1e-50 170.0 22.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PXF47929.1 - 0.21 10.9 10.0 0.29 10.4 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein TMEM247 PF15444.6 PXF47929.1 - 1.1 9.3 9.6 2 8.4 9.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 PA26 PF04636.13 PXF47929.1 - 4.3 6.2 5.4 5.8 5.7 5.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CRA PF06589.11 PXF47929.1 - 8.8 6.5 6.5 22 5.2 6.5 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Pkinase PF00069.25 PXF47930.1 - 6.4e-68 229.0 0.0 7.9e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF47930.1 - 5.8e-32 111.0 0.0 7.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF47930.1 - 1.7e-09 37.4 0.0 4.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PXF47930.1 - 2.6e-07 30.8 0.3 5e-05 23.3 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PXF47930.1 - 0.00019 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF47930.1 - 0.0038 16.9 0.3 0.015 14.9 0.3 1.8 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PXF47930.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GalKase_gal_bdg PF10509.9 PXF47931.1 - 3.6e-20 71.2 0.0 9.7e-20 69.9 0.0 1.8 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 PXF47931.1 - 5.8e-13 49.0 0.0 3e-12 46.7 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PXF47931.1 - 1.9e-11 44.0 0.5 4.4e-11 42.9 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF3008 PF11450.8 PXF47931.1 - 0.011 15.9 0.5 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Nramp PF01566.18 PXF47931.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein DEAD PF00270.29 PXF47932.1 - 1.2e-39 135.9 0.1 2.1e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF47932.1 - 1.1e-21 77.2 0.0 6.7e-21 74.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF47932.1 - 3.6e-07 30.3 2.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GPP34 PF05719.11 PXF47932.1 - 0.0091 16.1 3.5 0.0091 16.1 3.5 1.9 2 0 0 2 2 2 1 Golgi phosphoprotein 3 (GPP34) CMS1 PF14617.6 PXF47932.1 - 0.037 13.4 0.0 0.037 13.4 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 PXF47932.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain GIDA PF01134.22 PXF47933.1 - 3.5e-133 444.5 0.0 4.7e-133 444.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 PXF47933.1 - 7.8e-66 222.2 0.2 1.1e-65 221.7 0.2 1.2 1 0 0 1 1 1 1 GidA associated domain AAA_12 PF13087.6 PXF47934.1 - 2.1e-45 154.8 0.0 1.6e-44 152.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Dna2 PF08696.11 PXF47934.1 - 3.5e-45 154.3 0.0 1.5e-44 152.3 0.0 2.0 3 0 0 3 3 2 1 DNA replication factor Dna2 AAA_11 PF13086.6 PXF47934.1 - 1.7e-31 110.0 1.9 4e-15 56.3 0.1 2.8 2 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 PXF47934.1 - 1.7e-15 57.3 0.0 4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PXF47934.1 - 4.4e-10 40.1 0.0 1.2e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 PXF47934.1 - 3.1e-06 27.3 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 PXF47934.1 - 0.00028 20.7 0.7 2.3 7.9 0.0 3.7 3 1 1 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 PXF47934.1 - 0.0015 18.4 0.0 0.0077 16.1 0.0 2.2 1 1 0 1 1 1 1 Helicase T2SSE PF00437.20 PXF47934.1 - 0.0024 17.0 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 PXF47934.1 - 0.0039 17.2 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PC-Esterase PF13839.6 PXF47934.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SRP54 PF00448.22 PXF47934.1 - 0.0059 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 PXF47934.1 - 0.0082 15.7 0.0 0.022 14.3 0.0 1.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 PXF47934.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain FtsK_SpoIIIE PF01580.18 PXF47934.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Herpes_ori_bp PF02399.15 PXF47934.1 - 0.014 13.5 0.0 0.022 12.8 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein ABC_tran PF00005.27 PXF47934.1 - 0.033 14.7 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 PXF47934.1 - 0.053 13.9 0.1 0.57 10.6 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PXF47934.1 - 0.056 13.7 0.2 0.41 10.9 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF47934.1 - 0.063 13.7 0.1 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 PXF47934.1 - 0.075 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 PXF47934.1 - 0.097 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PXF47934.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 PXF47934.1 - 0.12 12.1 0.2 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PXF47934.1 - 0.14 11.9 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 PXF47934.1 - 0.16 11.2 0.2 0.83 8.8 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 PXF47934.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF47934.1 - 0.28 11.6 4.4 1.6 9.2 0.4 2.6 1 1 1 2 2 2 0 AAA domain Ribosomal_L4 PF00573.22 PXF47935.1 - 9e-40 136.4 0.1 1.2e-39 135.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 PXF47935.1 - 6.6e-23 80.6 3.4 6.6e-23 80.6 3.4 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain SPRY PF00622.28 PXF47936.1 - 9.8e-11 41.8 0.0 2.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Peptidase_M41 PF01434.18 PXF47937.1 - 0.16 11.8 0.7 0.7 9.7 0.7 2.0 1 1 0 1 1 1 0 Peptidase family M41 WD40 PF00400.32 PXF47940.1 - 4.6e-42 141.2 22.0 3.7e-07 30.7 0.0 9.6 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF47940.1 - 2.6e-12 46.8 2.6 0.029 14.7 0.1 7.3 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF47940.1 - 9e-08 31.4 0.4 1.2 8.0 0.0 4.6 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 PXF47940.1 - 0.00099 18.3 0.5 6.7 5.7 0.1 4.4 3 1 1 5 5 5 1 Protein of unknown function (DUF1513) DUF5046 PF16465.5 PXF47940.1 - 0.0026 17.3 0.0 0.25 10.7 0.0 3.0 2 2 2 4 4 4 1 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 PXF47940.1 - 0.0039 17.6 0.6 51 4.5 0.1 5.1 4 1 1 5 5 4 0 PQQ-like domain DUF727 PF05303.12 PXF47940.1 - 0.0039 17.2 1.0 1.4 9.0 0.0 4.2 3 2 2 5 5 5 1 Protein of unknown function (DUF727) PQQ_2 PF13360.6 PXF47940.1 - 0.0088 15.6 0.5 0.32 10.5 0.2 3.0 1 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.12 PXF47940.1 - 0.0089 16.0 0.3 18 5.4 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1668 PF07893.13 PXF47940.1 - 0.0095 15.3 0.0 4.3 6.6 0.0 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF1668) PQQ PF01011.21 PXF47940.1 - 0.026 14.4 0.1 6.2 6.9 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Frtz PF11768.8 PXF47940.1 - 0.026 12.8 0.1 0.32 9.3 0.1 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 PXF47940.1 - 0.038 12.7 3.1 11 4.5 0.1 3.9 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Hira PF07569.11 PXF47940.1 - 0.071 12.8 0.3 1.8 8.2 0.0 3.2 3 1 0 3 3 3 0 TUP1-like enhancer of split eIF2A PF08662.11 PXF47940.1 - 0.086 12.7 0.0 3.8 7.4 0.0 3.0 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A UPF0172 PF03665.13 PXF47941.1 - 9.5e-37 126.9 0.0 1.1e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Cas_VVA1548 PF09652.10 PXF47941.1 - 0.044 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) NusG PF02357.19 PXF47942.1 - 9.3e-12 45.3 0.1 2.3e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 PXF47942.1 - 8.3e-06 25.6 0.4 1.7e-05 24.6 0.4 1.5 1 0 0 1 1 1 1 KOW motif FKBP_C PF00254.28 PXF47943.1 - 8.1e-21 74.2 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mog1 PF04603.12 PXF47944.1 - 1.1e-33 116.5 0.0 1.4e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein zf-H2C2_2 PF13465.6 PXF47945.1 - 3.6e-06 27.2 8.4 6.2e-05 23.3 2.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 PXF47945.1 - 0.00092 19.5 7.0 0.0018 18.6 1.7 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF47945.1 - 0.82 10.7 9.4 0.18 12.7 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Auxin_repressed PF05564.12 PXF47946.1 - 0.27 11.9 7.6 0.4 11.4 7.4 1.4 1 1 0 1 1 1 0 Dormancy/auxin associated protein His_Phos_1 PF00300.22 PXF47947.1 - 1.7e-25 89.8 0.0 2.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_2 PF07724.14 PXF47948.1 - 7.6e-40 136.8 0.0 1.6e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 PXF47948.1 - 1.9e-14 54.2 0.1 5.3e-14 52.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PXF47948.1 - 7.7e-13 48.3 0.4 1.9e-12 47.1 0.4 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PXF47948.1 - 4.6e-07 29.9 0.0 2.4e-06 27.6 0.0 2.2 3 0 0 3 3 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 PXF47948.1 - 2.4e-06 26.8 0.1 4.7e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 PXF47948.1 - 6.8e-06 25.9 0.2 0.0002 21.1 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF47948.1 - 4.5e-05 23.7 0.4 0.00029 21.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PXF47948.1 - 0.00014 21.5 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PXF47948.1 - 0.00025 20.5 0.6 0.74 9.2 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PXF47948.1 - 0.00029 20.6 0.1 0.00073 19.3 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 PXF47948.1 - 0.00047 20.6 0.2 0.0036 17.7 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 PXF47948.1 - 0.00052 19.8 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 PXF47948.1 - 0.0012 19.4 0.2 0.0037 17.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Bac_DnaA PF00308.18 PXF47948.1 - 0.0027 17.6 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_14 PF13173.6 PXF47948.1 - 0.0058 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 PXF47948.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PXF47948.1 - 0.0074 16.7 0.0 0.024 15.0 0.0 1.9 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.12 PXF47948.1 - 0.012 15.5 0.0 0.2 11.6 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 PXF47948.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 PXF47948.1 - 0.03 13.2 0.6 0.053 12.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 PXF47948.1 - 0.033 14.3 0.1 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain KAP_NTPase PF07693.14 PXF47948.1 - 0.039 13.2 0.1 4.7 6.4 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 PXF47948.1 - 0.05 13.8 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PXF47948.1 - 0.093 13.0 0.2 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 PXF47948.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PXF47948.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter IPT PF01745.16 PXF47948.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Roc PF08477.13 PXF47948.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_M14 PF00246.24 PXF47949.1 - 2.7e-23 83.2 0.0 6.7e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 PXF47949.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_Tyr PF07714.17 PXF47950.1 - 5.3e-49 166.8 0.0 6.2e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF47950.1 - 6.8e-49 166.6 0.0 8.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PXF47950.1 - 2.5e-05 23.3 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PXF47950.1 - 0.0012 18.8 0.2 0.0029 17.6 0.2 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PXF47950.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PXF47950.1 - 0.013 15.1 0.1 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 PXF47950.1 - 0.046 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpb2_6 PF00562.28 PXF47951.1 - 2e-116 389.3 0.0 2.8e-116 388.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PXF47951.1 - 1.1e-54 185.0 0.1 1.7e-54 184.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 PXF47951.1 - 4.4e-33 113.5 1.1 1e-32 112.4 1.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 PXF47951.1 - 6e-20 71.2 0.0 1.3e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PXF47951.1 - 1.5e-19 70.1 0.1 4.1e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 PXF47951.1 - 3.2e-19 69.3 0.2 8.6e-11 41.8 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 PXF47951.1 - 1.6e-11 44.6 0.6 3.9e-11 43.3 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CTU2 PF10288.9 PXF47952.1 - 3.7e-05 23.9 4.3 9.4e-05 22.6 4.3 1.8 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 CYYR1 PF10873.8 PXF47952.1 - 0.29 11.6 2.2 0.54 10.7 2.2 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MAPEG PF01124.18 PXF47953.1 - 1.8e-11 44.0 2.0 2.2e-11 43.7 2.0 1.1 1 0 0 1 1 1 1 MAPEG family Uma2 PF05685.12 PXF47955.1 - 7.1e-26 90.8 0.0 9e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Pirin PF02678.16 PXF47956.1 - 4.9e-33 113.3 0.1 1.1e-31 109.0 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 PXF47956.1 - 1.6e-31 108.7 0.0 1.2e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 PXF47956.1 - 2e-05 24.2 1.1 0.18 11.6 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 PXF47956.1 - 0.0051 16.5 0.5 1.4 8.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) NDUFB11 PF17250.2 PXF47957.1 - 4.4e-12 46.5 0.2 4.7e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase 11 kDa subunit SAE2 PF08573.10 PXF47957.1 - 0.015 16.4 1.1 0.019 16.1 0.3 1.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Tn7_Tnp_TnsA_N PF08722.11 PXF47957.1 - 0.034 14.3 0.5 0.045 13.9 0.5 1.2 1 0 0 1 1 1 0 TnsA endonuclease N terminal DUF493 PF04359.14 PXF47958.1 - 2.9e-18 66.2 0.0 4.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Med20 PF08612.11 PXF47959.1 - 1.8e-07 30.8 0.0 2.7e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex pPIWI_RE_REase PF18154.1 PXF47959.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 REase associating with pPIWI_RE JAB PF01398.21 PXF47960.1 - 1.3e-13 51.0 0.3 3.5e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PXF47960.1 - 5.4e-07 29.4 0.1 1.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PXF47960.1 - 0.17 11.9 0.0 1.5 8.8 0.0 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Rib_5-P_isom_A PF06026.14 PXF47961.1 - 4e-62 208.8 0.1 5e-62 208.6 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 PXF47961.1 - 0.027 14.4 0.1 1.2 9.1 0.1 2.2 1 1 0 1 1 1 0 DeoR C terminal sensor domain Methyltransf_16 PF10294.9 PXF47963.1 - 8.4e-24 84.2 0.1 1.7e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 PXF47963.1 - 1.1e-07 31.6 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 PXF47963.1 - 2.8e-07 31.1 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF47963.1 - 6.2e-07 29.3 0.0 9.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF47963.1 - 8.8e-06 25.3 0.3 1.3e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 PXF47963.1 - 8.7e-05 23.2 0.0 0.00044 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PXF47963.1 - 0.0024 17.5 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Polysacc_synt_2 PF02719.15 PXF47963.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NNMT_PNMT_TEMT PF01234.17 PXF47963.1 - 0.16 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 PXF47963.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NPFF PF15085.6 PXF47963.1 - 0.77 10.1 2.2 1.8 9.0 0.1 2.7 3 1 1 4 4 4 0 Neuropeptide FF RRM_1 PF00076.22 PXF47964.1 - 4.9e-19 67.9 0.0 9.1e-10 38.2 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PXF47964.1 - 7.9e-12 45.1 0.0 3.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 RRM_occluded PF16842.5 PXF47964.1 - 5.5e-08 32.6 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 PXF47964.1 - 0.00089 19.5 4.6 0.8 9.9 0.2 4.1 4 1 1 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 PXF47964.1 - 0.05 13.6 0.0 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 PXF47964.1 - 0.14 12.2 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain WD40 PF00400.32 PXF47965.1 - 1e-12 48.3 7.7 0.0011 19.7 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 PXF47965.1 - 0.011 16.1 0.1 12 6.5 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain ANAPC4_WD40 PF12894.7 PXF47965.1 - 0.014 15.7 0.0 0.69 10.2 0.0 3.4 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.23 PXF47965.1 - 0.035 14.2 0.3 0.035 14.2 0.3 2.8 3 0 0 3 3 3 0 Zinc knuckle LCM PF04072.14 PXF47967.1 - 1.7e-28 99.9 0.1 3.2e-28 99.0 0.1 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Abhydrolase_2 PF02230.16 PXF47968.1 - 2.8e-11 43.6 0.0 2.9e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 PXF47968.1 - 0.00037 21.2 0.2 0.00069 20.3 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF47968.1 - 0.0017 17.7 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 PXF47968.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 PXF47968.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF47968.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Utp14 PF04615.13 PXF47970.1 - 9.6e-123 411.3 88.7 7.6e-87 292.6 58.9 2.1 1 1 1 2 2 2 2 Utp14 protein DUF3619 PF12279.8 PXF47970.1 - 0.12 12.7 1.5 0.8 10.0 1.5 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Lyase_1 PF00206.20 PXF47971.1 - 1.5e-75 254.6 0.0 2.1e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 PXF47971.1 - 1.6e-18 67.2 0.0 4.3e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal COPIIcoated_ERV PF07970.12 PXF47972.1 - 2.6e-32 112.5 0.2 4.2e-32 111.8 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 PXF47972.1 - 3e-09 36.8 0.0 5.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin ERGIC_N PF13850.6 PXF47973.1 - 5.2e-21 74.8 0.0 7.7e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PFK PF00365.20 PXF47974.1 - 3.7e-62 210.2 1.0 5.4e-62 209.7 0.9 1.3 1 1 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 PXF47974.1 - 0.001 18.7 0.4 0.0024 17.5 0.1 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain TPP_enzyme_C PF02775.21 PXF47974.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ELFV_dehydrog PF00208.21 PXF47974.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Hydrolase_4 PF12146.8 PXF47975.1 - 0.055 12.7 0.0 0.088 12.1 0.0 1.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF47975.1 - 0.076 12.7 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_16 PF00722.21 PXF47976.1 - 6.8e-34 116.9 2.4 8.6e-34 116.5 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sulfotransfer_3 PF13469.6 PXF47977.1 - 0.0028 18.1 0.7 0.027 14.8 0.2 2.1 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PXF47977.1 - 0.056 12.9 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain Adeno_E3 PF06040.11 PXF47978.1 - 0.19 11.9 0.5 6.1 7.0 0.5 2.7 1 1 0 1 1 1 0 Adenovirus E3 protein APH PF01636.23 PXF47981.1 - 6e-07 29.6 0.2 2.2e-06 27.8 0.2 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF47981.1 - 0.0062 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase LepB_GAP_N PF18172.1 PXF47981.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain PPDK_N PF01326.19 PXF47983.1 - 2.6e-33 115.7 3.3 2.6e-31 109.1 3.3 2.0 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PPDK_N PF01326.19 PXF47984.1 - 1.9e-11 43.8 0.0 3.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ArsA_ATPase PF02374.15 PXF47985.1 - 3.2e-42 144.8 0.2 3.5e-42 144.7 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase PHM7_cyt PF14703.6 PXF47985.1 - 0.049 13.9 0.1 0.087 13.1 0.1 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Mod_r PF07200.13 PXF47985.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF883 PF05957.13 PXF47985.1 - 0.78 10.4 4.1 1.5 9.5 2.5 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb2_4 PF04566.13 PXF47986.1 - 8.1e-05 22.8 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 DUF525 PF04379.14 PXF47986.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 ApaG domain DUF1759 PF03564.15 PXF47987.1 - 0.0098 15.8 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) HalX PF08663.10 PXF47987.1 - 0.11 12.9 0.5 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 HalX domain DUF3751 PF12571.8 PXF47987.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.7 1 1 1 2 2 2 0 Phage tail-collar fibre protein DNA_pol3_alpha PF07733.12 PXF47991.1 - 1.7e-45 155.6 0.0 1.9e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain Plant_tran PF04827.14 PXF47995.1 - 0.00014 21.5 0.1 0.0002 21.0 0.1 1.2 1 0 0 1 1 1 1 Plant transposon protein AIM24 PF01987.17 PXF47996.1 - 4.4e-43 147.4 0.1 4.9e-43 147.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Regulator_TrmB PF11495.8 PXF47996.1 - 0.026 13.7 0.1 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB TAF6_C PF07571.13 PXF47996.1 - 0.097 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain FA_desaturase PF00487.24 PXF47998.1 - 2.6e-30 106.1 22.6 4.4e-30 105.3 22.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 PXF47998.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF1963 PF09234.10 PXF47999.1 - 0.00011 22.7 0.0 0.0005 20.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1963) CENP-B_dimeris PF09026.10 PXF47999.1 - 0.00055 20.3 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 Centromere protein B dimerisation domain Peptidase_C78 PF07910.13 PXF48000.1 - 6.5e-46 156.5 0.1 1.2e-45 155.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C78 NTP_transf_4 PF13562.6 PXF48000.1 - 0.042 14.1 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Sugar nucleotidyl transferase DUF364 PF04016.12 PXF48000.1 - 0.065 12.8 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Peptidase_C54 PF03416.19 PXF48000.1 - 0.085 12.3 0.7 1.8 7.9 0.3 2.6 2 1 0 2 2 2 0 Peptidase family C54 PBP PF01161.20 PXF48001.1 - 3.6e-08 33.8 0.1 3.6e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein UPF0126 PF03458.13 PXF48002.1 - 5.7e-36 122.3 27.9 7.9e-20 70.5 5.5 2.9 2 1 1 3 3 3 2 UPF0126 domain TetR_C_33 PF13305.6 PXF48002.1 - 2.4 8.9 14.1 0.4 11.4 5.1 3.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EF-hand_6 PF13405.6 PXF48003.1 - 7.8e-10 37.9 4.6 0.0015 18.3 0.2 4.1 4 1 2 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 PXF48003.1 - 5.7e-09 34.9 5.9 0.0024 17.3 0.0 4.3 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 PXF48003.1 - 2.8e-08 34.1 1.9 0.0035 17.8 0.1 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 PXF48003.1 - 0.0011 19.2 0.4 0.019 15.3 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PXF48003.1 - 0.02 14.7 4.5 0.078 12.8 0.2 3.3 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.6 PXF48003.1 - 0.2 11.2 0.0 0.2 11.2 0.0 3.8 4 1 0 4 4 4 0 EF hand Myb_DNA-binding PF00249.31 PXF48004.1 - 5.4e-06 26.5 0.4 1e-05 25.6 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF48004.1 - 0.00028 21.1 0.0 0.0007 19.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain UCH PF00443.29 PXF48005.1 - 4.7e-42 144.2 0.0 2.2e-41 142.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF48005.1 - 5.1e-17 62.4 0.1 2.7e-16 60.1 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sua5_yciO_yrdC PF01300.18 PXF48005.1 - 0.0077 15.7 0.1 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination Peptidase_C98 PF15499.6 PXF48005.1 - 0.049 13.1 1.9 1.1 8.7 1.9 2.6 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EMC3_TMCO1 PF01956.16 PXF48006.1 - 5.1e-23 81.7 0.0 6.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like FPN1 PF06963.12 PXF48006.1 - 0.015 13.9 0.1 0.018 13.6 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2721 PF11026.8 PXF48006.1 - 0.021 14.7 0.4 0.043 13.7 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) AAA_23 PF13476.6 PXF48006.1 - 0.31 11.5 2.5 0.4 11.1 2.5 1.1 1 0 0 1 1 1 0 AAA domain UVR PF02151.19 PXF48006.1 - 6.9 6.6 7.2 0.64 9.8 2.2 1.9 2 0 0 2 2 2 0 UvrB/uvrC motif HSP70 PF00012.20 PXF48007.1 - 7.4e-246 817.0 8.2 9.2e-246 816.7 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PXF48007.1 - 7.5e-15 54.6 0.1 1.1e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 PXF48007.1 - 0.00058 20.2 1.7 0.35 11.3 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA FliJ PF02050.16 PXF48007.1 - 0.02 15.1 4.0 1.9 8.7 0.5 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DUF43 PF01861.16 PXF48007.1 - 0.087 12.0 1.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain Hydantoinase_A PF01968.18 PXF48007.1 - 0.17 11.1 1.2 2 7.6 0.1 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HCNGP PF07818.13 PXF48008.1 - 1.5e-09 38.4 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein AAA_assoc_C PF09821.9 PXF48009.1 - 0.047 14.2 0.9 0.75 10.3 0.0 2.9 2 1 0 3 3 3 0 C-terminal AAA-associated domain SAP PF02037.27 PXF48010.1 - 9.4e-11 41.2 1.5 1.9e-10 40.2 1.5 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 PXF48010.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain Cation_ATPase_N PF00690.26 PXF48010.1 - 1.6 8.4 3.5 14 5.5 0.0 3.5 3 1 0 3 3 3 0 Cation transporter/ATPase, N-terminus Ribosomal_L13e PF01294.18 PXF48011.1 - 5.7e-76 254.4 1.7 8.6e-76 253.8 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Mito_carr PF00153.27 PXF48012.1 - 1.8e-66 220.1 3.0 2.5e-23 81.8 0.1 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein Pkinase PF00069.25 PXF48013.1 - 2.6e-72 243.4 0.0 3e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48013.1 - 7.8e-37 126.9 0.0 9.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF48013.1 - 7e-11 42.0 0.0 1.5e-10 40.9 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF48013.1 - 2.4e-06 27.1 0.1 3.9e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF48013.1 - 0.00026 20.6 1.5 0.0004 20.0 0.2 1.9 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 PXF48013.1 - 0.00091 19.2 0.0 0.062 13.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 PXF48013.1 - 0.011 15.4 0.0 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PXF48013.1 - 0.031 13.2 0.1 0.045 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 PXF48013.1 - 0.12 12.0 0.1 0.32 10.5 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase MscS_TM PF12794.7 PXF48015.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF993 PF06187.11 PXF48016.1 - 0.033 13.1 0.0 0.033 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF993) VCBS PF13517.6 PXF48023.1 - 4.5e-29 100.8 36.3 5.5e-11 42.9 5.5 6.1 3 2 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF48023.1 - 1.8e-08 34.4 30.5 0.01 15.9 0.3 6.2 7 0 0 7 7 7 5 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF48023.1 - 1.8e-06 27.8 0.2 3.5e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 ASPIC and UnbV PP2C PF00481.21 PXF48024.1 - 1.6e-44 152.5 0.0 2.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF48024.1 - 2e-11 43.9 0.4 8.7e-11 41.9 0.4 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C ATP-grasp_4 PF13535.6 PXF48026.1 - 1.3e-22 80.1 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PXF48026.1 - 1.5e-10 40.9 0.1 1.2e-09 38.0 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PXF48026.1 - 6.5e-08 32.8 0.0 6e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PXF48026.1 - 2.5e-06 27.2 0.2 0.01 15.4 0.2 2.4 1 1 1 2 2 2 2 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 PXF48026.1 - 2.5e-05 23.9 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 PXF48026.1 - 0.00013 21.8 0.0 1.5 8.6 0.0 3.1 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 PXF48026.1 - 0.00021 21.4 1.4 0.00055 20.0 0.0 2.4 3 0 0 3 3 3 1 L-amino acid ligase C-terminal domain 2 ATP-grasp PF02222.22 PXF48026.1 - 0.00065 19.3 0.0 0.0034 17.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 PXF48026.1 - 0.0012 18.4 0.0 0.08 12.5 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_N PF18130.1 PXF48026.1 - 0.0025 18.4 0.0 0.0096 16.5 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Methyltransf_11 PF08241.12 PXF48027.1 - 4.2e-13 49.8 0.0 8.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF48027.1 - 1.7e-12 47.9 0.0 3.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF48027.1 - 5.8e-12 45.6 0.0 8.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF48027.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF48027.1 - 1.5e-09 37.5 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PXF48027.1 - 1.6e-07 32.0 0.0 2.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF48027.1 - 4.4e-05 22.9 0.0 0.00081 18.8 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 PXF48027.1 - 0.00035 19.9 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 PXF48027.1 - 0.00066 20.7 0.1 0.0096 16.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 PXF48027.1 - 0.043 13.3 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 PXF48027.1 - 0.048 13.2 0.1 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain SAM_MT PF04445.13 PXF48027.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_32 PF13679.6 PXF48027.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PXF48028.1 - 1.8e-07 31.1 0.0 3.1e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF48028.1 - 4.7e-07 30.4 0.1 1.2e-06 29.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF48028.1 - 3.8e-05 23.5 0.0 0.00026 20.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF48028.1 - 0.00012 22.8 0.1 0.00029 21.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF48028.1 - 0.00016 22.3 0.2 0.00052 20.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 PXF48028.1 - 0.00027 21.9 0.7 0.00087 20.3 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF48028.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 PXF48028.1 - 0.021 14.7 0.1 0.042 13.7 0.1 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase RIO1 PF01163.22 PXF48029.1 - 0.00039 20.1 0.1 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PXF48029.1 - 0.0052 16.7 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 PXF48031.1 - 9.6e-10 38.3 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PXF48031.1 - 0.0005 19.5 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF48031.1 - 0.00082 19.0 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PXF48031.1 - 0.0026 17.1 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF48031.1 - 0.0044 17.0 0.4 0.0077 16.2 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PP2C PF00481.21 PXF48032.1 - 1.8e-43 149.0 0.1 2.3e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF48032.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DEAD PF00270.29 PXF48033.1 - 1.2e-31 109.8 0.2 5.2e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48033.1 - 4.1e-23 81.8 0.1 1.4e-22 80.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48033.1 - 5.4e-07 29.8 0.0 9.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PXF48033.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Radical_SAM PF04055.21 PXF48034.1 - 0.00066 20.1 0.2 0.0016 18.8 0.2 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 PXF48034.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Pkinase_Tyr PF07714.17 PXF48035.1 - 1.8e-48 165.1 0.0 3.2e-46 157.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PXF48035.1 - 1.5e-39 135.9 0.0 1.5e-36 126.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 PXF48035.1 - 0.00062 18.7 0.0 0.00095 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_10 PF13673.7 PXF48037.1 - 5e-07 29.7 0.0 9.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF48037.1 - 2.5e-06 27.7 0.1 8.2e-06 26.0 0.0 1.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF48037.1 - 6.4e-06 26.5 0.0 1.7e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PXF48037.1 - 0.0025 17.9 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain STAG PF08514.11 PXF48039.1 - 4.9e-07 29.7 4.9 1.5e-06 28.1 4.9 1.9 1 1 0 1 1 1 1 STAG domain FapA PF03961.13 PXF48039.1 - 0.036 12.7 0.7 0.04 12.5 0.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CREPT PF16566.5 PXF48039.1 - 0.075 13.2 1.5 0.1 12.8 1.5 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour FAM76 PF16046.5 PXF48039.1 - 0.085 12.2 2.9 0.1 12.0 2.9 1.1 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 PXF48039.1 - 0.12 11.2 2.7 0.17 10.8 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4337 PF14235.6 PXF48039.1 - 0.39 10.8 1.9 0.55 10.3 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) QWRF PF04484.12 PXF48040.1 - 0.018 14.8 6.8 0.026 14.3 6.8 1.3 1 0 0 1 1 1 0 QWRF family TFIIA PF03153.13 PXF48040.1 - 0.071 13.1 13.6 0.084 12.9 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.15 PXF48040.1 - 0.33 10.4 6.7 0.54 9.7 6.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Glyoxalase PF00903.25 PXF48042.1 - 2.2e-08 34.4 0.1 1.9e-07 31.3 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_1 PF00036.32 PXF48042.1 - 7.6e-08 31.4 0.1 3.5e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF48042.1 - 4.8e-07 29.2 0.1 0.0028 17.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PXF48042.1 - 5.7e-06 26.7 0.4 0.025 15.0 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PXF48042.1 - 0.00022 21.0 0.2 0.0057 16.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair Glyoxalase_4 PF13669.6 PXF48042.1 - 0.0021 18.3 0.0 0.0062 16.8 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Dockerin_1 PF00404.18 PXF48042.1 - 0.026 14.7 0.0 7.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_5 PF13202.6 PXF48042.1 - 0.026 14.0 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 EF hand Glyoxalase_6 PF18029.1 PXF48042.1 - 0.03 15.1 0.0 0.24 12.2 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain HTH_11 PF08279.12 PXF48043.1 - 0.016 15.1 0.0 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 HTH domain PI3K_P85_iSH2 PF16454.5 PXF48044.1 - 8.5e-05 22.2 10.7 0.022 14.4 3.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Filament PF00038.21 PXF48044.1 - 0.00013 21.6 14.1 0.0073 15.9 2.7 2.1 2 0 0 2 2 2 2 Intermediate filament protein Rab5-bind PF09311.11 PXF48044.1 - 0.00031 20.2 15.9 0.015 14.7 3.3 3.1 2 1 0 2 2 2 2 Rabaptin-like protein Jnk-SapK_ap_N PF09744.9 PXF48044.1 - 0.0031 17.7 16.1 0.056 13.7 7.1 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 ADIP PF11559.8 PXF48044.1 - 0.0054 16.8 20.5 0.028 14.5 3.6 2.3 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.20 PXF48044.1 - 0.023 14.1 16.1 0.046 13.1 6.5 2.2 2 0 0 2 2 2 0 Tropomyosin DUF2730 PF10805.8 PXF48044.1 - 0.042 14.0 5.5 0.18 11.9 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF3584 PF12128.8 PXF48044.1 - 0.11 10.0 17.6 0.14 9.6 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 PXF48044.1 - 0.12 11.3 25.6 0.02 13.8 5.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 PXF48044.1 - 0.14 12.2 19.1 1.3 9.1 8.0 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF16 PF01519.16 PXF48044.1 - 0.16 12.5 11.6 0.73 10.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Prominin PF05478.11 PXF48044.1 - 0.24 9.3 13.1 0.13 10.2 1.7 2.1 2 0 0 2 2 2 0 Prominin MatP_C PF17414.2 PXF48044.1 - 0.27 11.5 4.9 7.3 6.9 0.3 3.7 4 0 0 4 4 3 0 MatP C-terminal ribbon-helix-helix domain Fib_alpha PF08702.10 PXF48044.1 - 0.34 11.1 11.9 0.89 9.7 4.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 PXF48044.1 - 0.38 11.3 16.5 0.55 10.8 7.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 PXF48044.1 - 0.42 10.7 17.9 2 8.5 2.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 PXF48044.1 - 0.44 10.8 14.2 0.93 9.8 1.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF745 PF05335.13 PXF48044.1 - 0.45 10.2 29.1 0.046 13.4 6.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF2508 PF10704.9 PXF48044.1 - 0.78 10.0 9.7 1.3 9.2 0.4 3.3 3 1 0 4 4 3 0 Protein of unknown function (DUF2508) TMPIT PF07851.13 PXF48044.1 - 1.1 8.5 13.8 2.8 7.1 1.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein PRKG1_interact PF15898.5 PXF48044.1 - 1.2 10.1 13.3 1.6 9.6 5.4 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain BLOC1_2 PF10046.9 PXF48044.1 - 1.3 9.4 17.7 1.8 8.9 3.6 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 PXF48044.1 - 1.5 7.8 13.6 0.4 9.7 0.6 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Goodbye PF17109.5 PXF48044.1 - 1.5 9.3 6.5 3.5 8.1 0.3 2.8 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain MscS_porin PF12795.7 PXF48044.1 - 1.7 8.1 23.5 0.77 9.3 3.2 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Seryl_tRNA_N PF02403.22 PXF48044.1 - 1.8 8.8 15.7 0.76 10.0 1.0 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cauli_AT PF03233.13 PXF48044.1 - 1.9 8.4 6.5 3.9 7.4 1.7 2.2 2 0 0 2 2 2 0 Aphid transmission protein AAA_13 PF13166.6 PXF48044.1 - 2.1 6.9 18.8 15 4.1 8.6 2.1 1 1 1 2 2 2 0 AAA domain Med9 PF07544.13 PXF48044.1 - 2.3 8.4 10.9 1.9 8.6 0.6 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sin3_corepress PF08295.12 PXF48044.1 - 2.6 8.2 6.9 1.4 9.0 1.8 2.8 2 1 0 2 2 2 0 Sin3 family co-repressor LMBR1 PF04791.16 PXF48044.1 - 2.7 6.8 6.0 3.8 6.3 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3391 PF11871.8 PXF48044.1 - 2.9 8.4 10.7 1.7 9.2 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Bud13 PF09736.9 PXF48044.1 - 2.9 8.3 9.8 49 4.3 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Sec8_exocyst PF04048.14 PXF48044.1 - 3 7.7 12.4 5.4 6.9 2.5 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain FemAB PF02388.16 PXF48044.1 - 3 6.6 11.2 5.9 5.7 4.7 2.1 2 0 0 2 2 2 0 FemAB family TraG_N PF07916.11 PXF48044.1 - 3.1 6.5 9.6 0.06 12.2 2.1 1.7 2 0 0 2 2 2 0 TraG-like protein, N-terminal region DUF641 PF04859.12 PXF48044.1 - 4.3 7.7 17.6 1.6 9.0 1.3 2.7 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) CREPT PF16566.5 PXF48044.1 - 6 7.0 11.6 5 7.3 1.8 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1515 PF07439.11 PXF48044.1 - 7.3 6.7 7.1 21 5.2 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Uso1_p115_C PF04871.13 PXF48044.1 - 7.4 7.0 20.5 3.1 8.2 8.9 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FliD_N PF02465.18 PXF48044.1 - 8.6 7.1 19.4 0.5 11.1 2.0 3.3 2 1 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus DASH_Spc19 PF08287.11 PXF48044.1 - 10 6.0 17.6 1.8 8.4 4.0 2.4 1 1 1 2 2 2 0 Spc19 DapH_N PF08503.10 PXF48045.1 - 0.045 14.0 0.2 0.44 10.8 0.0 2.8 2 1 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF2316 PF10078.9 PXF48045.1 - 0.061 13.6 0.0 0.061 13.6 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Actin PF00022.19 PXF48046.1 - 7.8e-44 149.9 0.0 9.2e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 PXF48047.1 - 1.8e-33 115.7 0.0 2.1e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Actin VirE PF05272.11 PXF48047.1 - 0.2 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Virulence-associated protein E Xpo1 PF08389.12 PXF48048.1 - 7.5e-06 26.1 0.1 3.6e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Exportin 1-like protein Dicty_REP PF05086.12 PXF48049.1 - 4.3 5.2 7.7 4.2 5.2 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_5 PF14634.6 PXF48050.1 - 6.8e-09 35.5 10.0 1.1e-08 34.9 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PXF48050.1 - 7.1e-07 29.0 10.2 1.3e-06 28.1 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF48050.1 - 4.1e-06 27.0 10.0 6.4e-06 26.4 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PXF48050.1 - 1.6e-05 24.6 7.7 3.6e-05 23.5 7.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PXF48050.1 - 0.00013 21.8 9.9 0.00021 21.1 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF48050.1 - 0.00035 20.4 8.1 0.00055 19.7 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ABC_tran_CTD PF16326.5 PXF48050.1 - 0.0062 16.8 7.7 0.031 14.5 4.3 2.5 1 1 1 2 2 2 2 ABC transporter C-terminal domain zf-rbx1 PF12678.7 PXF48050.1 - 0.0088 16.3 8.6 0.017 15.4 8.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 PXF48050.1 - 0.0093 15.8 3.0 0.016 15.0 3.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 PXF48050.1 - 0.01 15.8 5.4 0.019 15.0 5.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Nup54 PF13874.6 PXF48050.1 - 0.023 14.8 6.1 0.047 13.8 6.1 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Fmp27_WPPW PF10359.9 PXF48050.1 - 0.034 13.0 1.2 0.04 12.8 1.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Latarcin PF10279.9 PXF48050.1 - 0.05 14.0 0.6 0.05 14.0 0.6 2.4 1 1 1 2 2 2 0 Latarcin precursor zf-RING_10 PF16685.5 PXF48050.1 - 0.061 13.5 8.7 0.11 12.7 8.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Spc7 PF08317.11 PXF48050.1 - 0.11 11.3 7.5 0.12 11.2 6.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 PXF48050.1 - 0.19 12.3 5.5 0.55 10.9 0.2 2.4 2 0 0 2 2 2 0 SlyX TACC_C PF05010.14 PXF48050.1 - 0.21 11.4 8.1 0.31 10.8 8.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_11 PF17123.5 PXF48050.1 - 0.22 11.3 3.4 0.47 10.2 3.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger KELK PF15796.5 PXF48050.1 - 0.3 11.6 10.1 0.49 10.9 1.4 2.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 PXF48050.1 - 0.55 9.6 12.6 0.21 10.9 10.0 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 PXF48050.1 - 0.7 9.7 6.9 1.7 8.4 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CtIP_N PF10482.9 PXF48050.1 - 0.77 9.8 11.4 0.042 13.9 4.3 2.3 2 1 0 3 3 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 PXF48050.1 - 1.2 8.4 7.9 1.8 7.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 PXF48050.1 - 1.8 9.3 7.3 6.1 7.5 7.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 PXF48050.1 - 1.8 8.7 12.1 1 9.4 3.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 PXF48050.1 - 2.8 8.2 13.4 6.9 6.9 13.4 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CorA PF01544.18 PXF48050.1 - 3 7.1 4.3 4.4 6.5 4.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C3HC4_4 PF15227.6 PXF48050.1 - 3.2 8.0 10.1 11 6.3 10.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4164 PF13747.6 PXF48050.1 - 3.3 8.0 11.7 5.9 7.3 2.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Zn_ribbon_17 PF17120.5 PXF48050.1 - 5 6.8 9.2 8.3 6.1 9.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 PXF48050.1 - 7.6 6.3 8.4 13 5.5 8.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger Rcd1 PF04078.13 PXF48051.1 - 1.1e-126 421.5 0.7 1.2e-126 421.3 0.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF742 PF05331.11 PXF48051.1 - 0.1 12.4 0.5 1.5 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) ArfGap PF01412.18 PXF48052.1 - 1.8e-42 144.1 1.0 3.5e-42 143.2 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 PXF48052.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF2205 PF10224.9 PXF48053.1 - 0.36 10.8 4.6 0.74 9.9 0.2 3.1 2 1 1 3 3 3 0 Short coiled-coil protein EF-hand_1 PF00036.32 PXF48054.1 - 5.6e-12 44.3 1.3 2.4e-05 23.6 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PXF48054.1 - 1.2e-11 44.8 0.4 3.4e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PXF48054.1 - 1.9e-11 42.9 0.9 2.7e-05 23.8 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain Na_Ca_ex PF01699.24 PXF48054.1 - 7.5e-11 42.2 27.9 1.4e-08 34.9 14.8 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_5 PF13202.6 PXF48054.1 - 5.2e-09 35.2 1.6 0.00069 19.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PXF48054.1 - 9.8e-05 22.1 0.6 0.00026 20.7 0.4 1.9 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PXF48054.1 - 0.013 15.8 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PAXIP1_C PF15364.6 PXF48054.1 - 0.16 12.3 3.7 0.38 11.0 3.7 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3784 PF12650.7 PXF48054.1 - 5.7 7.2 17.3 0.19 11.9 4.7 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3784) DUF1201 PF06716.11 PXF48054.1 - 8.2 6.5 7.7 27 4.9 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) DUF3395 PF11875.8 PXF48055.1 - 1.3e-30 106.3 0.4 2.1e-30 105.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PXF48055.1 - 6.7e-18 64.6 1.0 1.3e-17 63.6 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Halogen_Hydrol PF10112.9 PXF48055.1 - 0.025 14.6 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Med30 PF11315.8 PXF48055.1 - 0.12 12.5 0.2 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 NES_C_h PF18208.1 PXF48056.1 - 0.015 15.6 0.8 0.037 14.3 0.1 1.8 1 1 1 2 2 2 0 Nicking enzyme C-terminal middle helical domain Acyltransf_C PF16076.5 PXF48056.1 - 0.11 12.6 0.2 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 Acyltransferase C-terminus UCH_1 PF13423.6 PXF48057.1 - 5.5e-52 177.3 0.0 7.3e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 PXF48057.1 - 1.5e-18 67.9 0.0 2.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 PXF48057.1 - 0.1 12.0 0.5 13 5.1 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Ion_trans_2 PF07885.16 PXF48058.1 - 2.4e-16 59.4 3.4 2.4e-16 59.4 3.4 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 PXF48058.1 - 3.6e-16 59.2 8.0 4.7e-16 58.8 8.0 1.1 1 0 0 1 1 1 1 Ion transport protein zf-ribbon_3 PF13248.6 PXF48058.1 - 0.027 13.9 0.7 0.049 13.0 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 PXF48058.1 - 0.044 13.8 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 PXF48058.1 - 0.097 12.6 0.2 0.097 12.6 0.2 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit RabGAP-TBC PF00566.18 PXF48059.1 - 3.8e-56 190.1 0.1 3.8e-56 190.1 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PSDC PF12588.8 PXF48059.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Rho_Binding PF08912.11 PXF48059.1 - 0.27 12.1 3.5 1.4 9.8 0.1 2.9 3 0 0 3 3 3 0 Rho Binding DEAD PF00270.29 PXF48060.1 - 1.2e-36 126.1 0.0 2.2e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48060.1 - 1.2e-18 67.5 0.0 1.8e-17 63.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48060.1 - 3.6e-07 30.4 0.0 1.7e-06 28.2 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF48060.1 - 0.2 11.9 1.3 0.81 10.0 0.1 2.6 2 2 0 2 2 2 0 AAA domain Ribosomal_L28e PF01778.17 PXF48061.1 - 2.9e-35 121.5 1.9 2.9e-35 121.5 1.9 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 PXF48061.1 - 1.1e-20 74.1 33.1 9.3e-20 71.1 33.1 2.5 1 1 0 1 1 1 1 Mak16 protein C-terminal region EELM2 PF15863.5 PXF48061.1 - 0.32 11.1 4.3 3.6 7.7 0.1 3.1 2 1 1 3 3 3 0 Extended EGL-27 and MTA1 homology domain KfrA_N PF11740.8 PXF48061.1 - 2.1 9.1 12.9 0.25 12.0 8.1 2.0 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Herpes_DNAp_acc PF04929.12 PXF48061.1 - 4 6.3 4.8 6 5.7 4.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.13 PXF48061.1 - 8.3 6.3 24.2 5.2 7.0 22.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4975 PF16346.5 PXF48062.1 - 0.041 14.0 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) F-box-like PF12937.7 PXF48063.1 - 1.2e-10 41.1 0.6 5.7e-10 38.9 0.6 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF48063.1 - 0.0067 16.3 1.0 0.082 12.8 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 PXF48063.1 - 0.23 11.6 1.4 63 4.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat RRM_1 PF00076.22 PXF48064.1 - 1.9e-15 56.4 0.0 2.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 PXF48064.1 - 4.1e-06 26.6 1.6 9.6e-06 25.4 0.2 2.3 3 0 0 3 3 3 1 zinc-ribbon domain DNA_topoisoIV PF00521.20 PXF48064.1 - 0.081 11.8 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RRM_7 PF16367.5 PXF48064.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif dCMP_cyt_deam_1 PF00383.23 PXF48065.1 - 6.6e-25 86.9 1.0 9.7e-25 86.4 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF48065.1 - 1.8e-23 82.8 0.0 2.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 PXF48065.1 - 0.00041 20.2 1.1 0.0012 18.7 1.1 1.7 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 PXF48065.1 - 0.001 19.2 1.3 0.12 12.4 0.1 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 PXF48065.1 - 0.0016 18.5 0.1 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 PXF48065.1 - 0.031 14.4 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 MAGP PF05507.11 PXF48065.1 - 0.07 13.5 0.5 0.13 12.7 0.5 1.4 1 1 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) APOBEC4_like PF18774.1 PXF48065.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase UBX PF00789.20 PXF48066.1 - 1.6e-05 25.0 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain Prok-E2_A PF14457.6 PXF48066.1 - 0.021 14.5 0.6 0.1 12.2 0.5 2.2 1 1 1 2 2 2 0 Prokaryotic E2 family A FlgT_N PF16548.5 PXF48066.1 - 3.6 8.2 6.5 0.69 10.5 2.0 2.2 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain TENA_THI-4 PF03070.16 PXF48067.1 - 8.2e-06 25.8 0.3 1.5e-05 24.9 0.3 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Tubulin_3 PF14881.6 PXF48068.1 - 6.2e-21 74.9 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 PXF48068.1 - 2.2e-19 69.9 0.2 4.3e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF640 PF04852.12 PXF48068.1 - 0.04 14.1 0.5 0.091 12.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Mg_trans_NIPA PF05653.14 PXF48069.1 - 3.7e-16 59.1 8.4 4e-09 36.0 0.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 PXF48069.1 - 0.00033 20.8 0.9 0.00033 20.8 0.9 2.9 3 1 0 3 3 3 1 EamA-like transporter family DUF2919 PF11143.8 PXF48069.1 - 0.53 10.6 8.4 0.097 13.0 4.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) FKBP_C PF00254.28 PXF48070.1 - 1.2e-12 48.0 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mito_carr PF00153.27 PXF48072.1 - 4.7e-56 186.7 1.7 1.6e-18 66.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myco_arth_vir_N PF09610.10 PXF48072.1 - 1.3 9.2 0.1 1.3 9.2 0.1 3.6 5 0 0 5 5 5 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Flavokinase PF01687.17 PXF48073.1 - 4.5e-29 101.0 0.0 6.2e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase ATP-sulfurylase PF01747.17 PXF48074.1 - 5.2e-56 189.5 0.0 8.3e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PXF48074.1 - 3.2e-29 101.7 0.0 7.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain E2F_TDP PF02319.20 PXF48075.1 - 1.7e-41 140.1 1.8 8.3e-21 73.8 0.1 3.1 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 PXF48075.1 - 0.00023 21.0 0.0 0.0033 17.3 0.0 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 PXF48075.1 - 0.011 15.8 0.1 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Cdc6_C PF09079.11 PXF48075.1 - 0.067 13.2 1.3 0.39 10.7 0.1 2.8 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain TBCA PF02970.16 PXF48076.1 - 8.4e-22 77.3 0.6 1e-21 77.0 0.6 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF1664 PF07889.12 PXF48076.1 - 0.051 13.6 0.8 0.16 12.0 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 PXF48076.1 - 0.099 12.9 1.5 1.1 9.5 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.6 PXF48076.1 - 0.1 13.3 1.1 0.21 12.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) NPV_P10 PF05531.12 PXF48076.1 - 0.2 12.2 2.3 5.6 7.5 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec20 PF03908.13 PXF48076.1 - 0.22 11.4 1.4 0.71 9.8 0.5 2.0 1 1 1 2 2 2 0 Sec20 NTP_transf_3 PF12804.7 PXF48077.1 - 3.6e-15 56.7 0.1 5.7e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 PXF48077.1 - 8e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 PXF48077.1 - 4.4e-08 33.3 0.0 6.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.19 PXF48077.1 - 3.3e-05 23.7 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pex14_N PF04695.13 PXF48078.1 - 1.7e-15 58.0 16.2 3.4e-15 57.0 8.1 3.3 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1465 PF07323.12 PXF48078.1 - 0.028 14.3 3.1 0.068 13.0 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) FUSC PF04632.12 PXF48078.1 - 0.03 12.9 1.4 0.051 12.1 1.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_M3 PF01432.20 PXF48079.1 - 4.2e-111 372.4 0.0 5.1e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 NOD PF06816.13 PXF48079.1 - 0.075 12.7 0.2 2.8 7.6 0.0 3.3 4 0 0 4 4 4 0 NOTCH protein TatD_DNase PF01026.21 PXF48079.1 - 0.12 11.8 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 TatD related DNase ESCRT-II PF05871.12 PXF48080.1 - 2.2e-45 154.4 0.0 2.9e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Sel1 PF08238.12 PXF48081.1 - 3e-39 132.6 16.5 1.2e-05 25.8 0.0 9.8 10 0 0 10 10 10 8 Sel1 repeat TPR_16 PF13432.6 PXF48081.1 - 0.047 14.3 20.4 0.099 13.3 0.0 6.2 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 PXF48081.1 - 0.051 14.0 1.8 5.1 7.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Arg_decarb_HB PF17810.1 PXF48081.1 - 0.1 12.9 0.1 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain TPR_6 PF13174.6 PXF48081.1 - 0.19 12.4 8.9 36 5.3 0.0 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 PXF48081.1 - 0.2 11.8 9.6 14 6.0 0.2 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 PXF48081.1 - 0.38 10.5 6.7 0.36 10.6 0.7 4.0 4 1 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 PXF48081.1 - 0.42 10.5 11.7 2.2 8.2 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF48081.1 - 1.9 9.5 14.8 5.5 8.1 0.0 5.9 5 2 2 7 7 7 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 PXF48082.1 - 2e-81 274.6 0.2 1e-46 160.2 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF48082.1 - 3.7e-16 59.1 2.3 4.7e-16 58.8 0.8 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF48082.1 - 3.5e-08 33.4 0.2 1.6e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PXF48082.1 - 2.2e-07 30.3 0.7 2.2e-07 30.3 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 PXF48082.1 - 4.4e-06 26.3 0.1 1.1e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF48082.1 - 1.9e-05 24.0 0.2 6.9e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF48082.1 - 0.00011 22.7 0.3 0.00042 20.8 0.3 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF48082.1 - 0.00022 20.6 0.1 0.00039 19.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PXF48082.1 - 0.00027 19.8 0.0 0.00072 18.4 0.0 1.7 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PXF48082.1 - 0.00032 20.1 0.4 0.00073 18.9 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PXF48082.1 - 0.00069 19.0 0.3 0.00069 19.0 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 PXF48082.1 - 0.011 15.0 0.2 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF48082.1 - 0.021 13.9 1.1 0.041 12.9 1.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A PAS_6 PF08348.11 PXF48082.1 - 0.14 12.0 0.6 0.6 10.0 0.3 2.2 2 0 0 2 2 2 0 YheO-like PAS domain Lycopene_cycl PF05834.12 PXF48082.1 - 0.2 10.6 0.2 0.32 10.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UPF0061 PF02696.14 PXF48085.1 - 4.9e-137 457.5 0.0 6.5e-137 457.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4863 PF16155.5 PXF48085.1 - 0.13 12.1 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) Yae1_N PF09811.9 PXF48086.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PspA_IM30 PF04012.12 PXF48087.1 - 6.3e-51 173.1 21.4 8.1e-51 172.7 21.4 1.1 1 0 0 1 1 1 1 PspA/IM30 family Fib_alpha PF08702.10 PXF48087.1 - 0.0052 17.0 9.8 0.0052 17.0 6.1 2.5 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Fic_N PF13784.6 PXF48087.1 - 0.023 14.7 0.3 0.067 13.2 0.1 1.9 2 0 0 2 2 2 0 Fic/DOC family N-terminal Phage_holin_7_1 PF16081.5 PXF48087.1 - 0.025 14.8 8.2 0.51 10.5 1.0 2.7 2 1 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Exotox-A_target PF09102.10 PXF48087.1 - 0.028 14.4 1.2 0.07 13.1 0.2 2.1 1 1 0 2 2 2 0 Exotoxin A, targeting DUF1664 PF07889.12 PXF48087.1 - 0.033 14.2 10.2 0.24 11.5 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 PXF48087.1 - 0.057 13.7 9.6 3.5 8.0 0.2 4.1 2 1 3 5 5 5 0 Tup N-terminal YscO PF07321.12 PXF48087.1 - 0.065 13.2 12.8 0.47 10.4 5.2 2.7 1 1 1 2 2 2 0 Type III secretion protein YscO Vps51 PF08700.11 PXF48087.1 - 0.079 13.1 3.3 2.3 8.4 0.1 3.6 3 0 0 3 3 3 0 Vps51/Vps67 DUF948 PF06103.11 PXF48087.1 - 0.12 12.6 6.0 4.6 7.6 1.2 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PXF48087.1 - 0.26 10.1 18.0 0.19 10.6 13.7 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF713 PF05218.14 PXF48087.1 - 0.43 10.3 4.2 2.6 7.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF713) Laminin_II PF06009.12 PXF48087.1 - 0.56 10.2 13.5 3.3 7.7 3.6 3.0 1 1 2 3 3 3 0 Laminin Domain II DASH_Dad4 PF08650.10 PXF48087.1 - 0.74 9.8 3.6 7.8 6.6 0.0 3.2 3 2 0 3 3 2 0 DASH complex subunit Dad4 CLZ PF16526.5 PXF48087.1 - 2.2 8.7 16.3 0.57 10.6 1.5 4.3 4 1 1 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C4H2 PF10146.9 PXF48087.1 - 2.8 8.2 10.5 1.7 8.9 2.6 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein V_ATPase_I PF01496.19 PXF48087.1 - 4.1 5.2 7.6 5.3 4.8 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Alanine_zipper PF11839.8 PXF48087.1 - 5.5 7.4 12.1 2.6 8.5 0.4 3.3 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Syntaxin-6_N PF09177.11 PXF48087.1 - 6.7 7.3 11.2 13 6.4 1.0 3.0 2 2 1 3 3 3 0 Syntaxin 6, N-terminal EMP24_GP25L PF01105.24 PXF48088.1 - 8.8e-23 81.2 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EMP24_GP25L PF01105.24 PXF48089.1 - 2e-19 70.2 5.4 1.1e-18 67.8 5.4 2.1 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3080 PF11279.8 PXF48089.1 - 0.019 14.2 0.9 0.029 13.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Radical_SAM PF04055.21 PXF48089.1 - 0.022 15.2 0.2 0.042 14.2 0.2 1.5 1 0 0 1 1 1 0 Radical SAM superfamily T3SS_needle_E PF08988.10 PXF48089.1 - 0.04 14.1 0.6 0.04 14.1 0.6 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle CorA PF01544.18 PXF48089.1 - 2.8 7.2 8.8 1.4 8.1 6.5 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein 14-3-3 PF00244.20 PXF48090.1 - 3.9e-101 337.2 6.0 4.5e-101 337.0 6.0 1.0 1 0 0 1 1 1 1 14-3-3 protein VASP_tetra PF08776.11 PXF48090.1 - 0.29 10.7 1.9 11 5.7 0.4 2.5 2 0 0 2 2 2 0 VASP tetramerisation domain HMG_box_5 PF14887.6 PXF48090.1 - 1.9 8.5 5.0 2.1 8.3 0.2 2.8 3 0 0 3 3 3 0 HMG (high mobility group) box 5 FHA PF00498.26 PXF48091.1 - 0.14 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 FHA domain DNA_photolyase PF00875.18 PXF48092.1 - 4.3e-16 59.4 0.3 1.6e-14 54.2 0.2 2.6 2 0 0 2 2 2 1 DNA photolyase Abhydrolase_6 PF12697.7 PXF48092.1 - 2.3e-15 57.8 0.0 2e-14 54.7 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF48092.1 - 4.8e-13 49.3 0.0 3.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF48092.1 - 1.9e-09 37.2 0.0 1.9e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 PXF48092.1 - 0.00063 19.5 0.0 1.1 8.8 0.0 2.7 2 1 0 2 2 2 2 Serine hydrolase (FSH1) His_Phos_1 PF00300.22 PXF48094.1 - 6.4e-11 42.3 0.0 8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TAT_signal PF10518.9 PXF48094.1 - 0.00026 20.7 0.4 0.00041 20.1 0.4 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Cpn60_TCP1 PF00118.24 PXF48095.1 - 2.3e-109 366.2 7.6 2.7e-109 366.0 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YbaB_DNA_bd PF02575.16 PXF48095.1 - 0.085 13.1 0.3 0.27 11.5 0.3 1.8 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family YbbR PF07949.12 PXF48095.1 - 0.17 12.2 1.7 6.4 7.2 0.1 2.4 2 0 0 2 2 2 0 YbbR-like protein CRM1_repeat PF18777.1 PXF48095.1 - 0.2 11.2 0.1 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Abhydrolase_6 PF12697.7 PXF48096.1 - 6e-27 95.7 0.2 6e-27 95.7 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF48096.1 - 2.9e-14 53.3 0.1 4e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PXF48096.1 - 2.4e-11 43.3 0.1 3.5e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PXF48096.1 - 0.0005 19.8 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 PXF48096.1 - 0.00062 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 PXF48096.1 - 0.00081 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 PXF48096.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 PXF48096.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DLH PF01738.18 PXF48096.1 - 0.0039 16.8 0.0 0.0093 15.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PXF48096.1 - 0.0042 17.0 2.9 0.026 14.4 2.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 PXF48096.1 - 0.0055 16.8 0.7 0.01 16.0 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.16 PXF48096.1 - 0.067 13.0 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PXF48096.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1057 PF06342.12 PXF48096.1 - 0.25 10.3 0.0 0.43 9.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) RRM_1 PF00076.22 PXF48097.1 - 7.8e-22 76.9 0.0 9.9e-22 76.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF48097.1 - 0.002 18.2 0.0 0.0042 17.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif AMPK1_CBM PF16561.5 PXF48098.1 - 4e-22 78.2 0.1 2.5e-21 75.7 0.0 2.3 3 0 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 PXF48098.1 - 6.8e-05 23.1 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPRY PF00622.28 PXF48098.1 - 0.0034 17.5 0.1 0.008 16.3 0.1 1.6 1 0 0 1 1 1 1 SPRY domain PapA_C PF16911.5 PXF48098.1 - 0.1 12.7 1.6 3.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Arf PF00025.21 PXF48099.1 - 2.5e-62 209.4 0.6 2.8e-62 209.3 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PXF48099.1 - 3.6e-13 49.4 0.4 5.5e-08 32.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PXF48099.1 - 5.1e-13 49.3 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF48099.1 - 2.4e-10 40.2 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PXF48099.1 - 3e-09 36.6 0.0 3.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PXF48099.1 - 2e-08 33.9 0.0 2.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF48099.1 - 2.2e-08 34.2 0.0 3.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PXF48099.1 - 0.00031 20.3 0.1 0.012 15.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PXF48099.1 - 0.014 15.0 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 PXF48099.1 - 0.024 14.2 0.1 0.078 12.5 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 PXF48099.1 - 0.028 14.2 0.0 0.074 12.8 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 PXF48099.1 - 0.081 13.5 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain cwf18 PF08315.12 PXF48100.1 - 1.4e-19 71.1 5.2 1.6e-19 70.9 5.2 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor LMBR1 PF04791.16 PXF48100.1 - 0.28 10.0 1.4 0.32 9.9 1.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_S24e PF01282.19 PXF48101.1 - 1.3e-32 111.5 0.0 2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Phosducin PF02114.16 PXF48102.1 - 7.5e-12 44.7 0.0 1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 PXF48102.1 - 0.00086 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF4455 PF14643.6 PXF48102.1 - 0.033 12.8 1.8 0.044 12.4 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF1798 PF08807.10 PXF48102.1 - 0.12 12.5 2.0 6.6 6.9 0.3 2.3 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) Elong_Iki1 PF10483.9 PXF48104.1 - 2.7e-06 27.1 1.3 7.5e-05 22.4 1.3 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 Trypsin PF00089.26 PXF48105.1 - 4.3e-25 88.8 0.0 8.3e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin Trypan_PARP PF05887.11 PXF48105.1 - 0.25 11.3 5.2 0.49 10.4 5.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 PXF48106.1 - 4.8e-46 157.2 0.0 6.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48106.1 - 1e-26 93.8 0.0 1.3e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF48106.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF48106.1 - 0.003 16.9 0.5 0.004 16.5 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF48106.1 - 0.0046 15.8 0.0 0.0071 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PXF48106.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PXF48106.1 - 0.19 10.6 0.8 0.31 9.9 0.8 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Y_phosphatase2 PF03162.13 PXF48107.1 - 4.2e-41 140.3 0.0 5.2e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PXF48107.1 - 0.00032 20.7 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF442 PF04273.13 PXF48107.1 - 0.2 11.8 0.0 0.41 10.7 0.0 1.5 1 1 0 1 1 1 0 Putative phosphatase (DUF442) RNA_pol_Rpc4 PF05132.14 PXF48108.1 - 2e-05 25.0 0.1 2e-05 25.0 0.1 3.3 4 1 0 4 4 4 1 RNA polymerase III RPC4 Exo_endo_phos PF03372.23 PXF48109.1 - 2.9e-23 82.6 0.0 4.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 PXF48109.1 - 0.035 14.4 0.8 0.035 14.4 0.8 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding RNB PF00773.19 PXF48110.1 - 3.6e-95 319.0 0.0 1.4e-94 317.1 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 PXF48110.1 - 1.9e-17 63.1 0.0 4.6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PXF48110.1 - 6.4e-14 51.9 0.0 1.5e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 PXF48110.1 - 4e-09 36.3 0.0 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 PXF48110.1 - 1.3e-07 31.7 0.6 7.4e-05 22.8 0.2 3.0 2 0 0 2 2 2 2 Cold shock domain Sec63 PF02889.16 PXF48111.1 - 2.7e-27 95.6 0.0 5.3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 PXF48111.1 - 2.2e-21 76.4 0.0 5.4e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48111.1 - 1.8e-10 41.1 0.0 2e-09 37.8 0.0 2.6 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48111.1 - 8.3e-08 32.4 0.0 2.6e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sin_N PF04801.13 PXF48111.1 - 0.039 13.2 0.1 0.076 12.2 0.1 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region AAA_22 PF13401.6 PXF48111.1 - 0.15 12.4 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain BTB PF00651.31 PXF48112.1 - 1e-09 38.6 0.1 2e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PXF48112.1 - 0.067 13.3 0.3 0.2 11.8 0.3 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch MOLO1 PF17175.4 PXF48113.1 - 2.7e-12 46.9 0.0 6.7e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Modulator of levamisole receptor-1 TPM_phosphatase PF04536.14 PXF48113.1 - 1.1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 TPM domain PHD PF00628.29 PXF48113.1 - 1.2 9.1 11.1 0.4 10.6 5.6 2.4 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 PXF48113.1 - 4.8 7.6 11.5 0.34 11.3 2.9 2.7 3 0 0 3 3 3 0 Ring finger domain Sec63 PF02889.16 PXF48116.1 - 1.3e-52 178.5 1.7 1.8e-52 178.0 0.3 1.9 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 PXF48116.1 - 3.9e-27 95.1 0.1 1.1e-26 93.7 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF48116.1 - 2.6e-11 43.8 0.0 7.6e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PXF48116.1 - 7.5e-08 32.3 0.8 3.2e-06 27.0 0.2 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PXF48116.1 - 0.00014 22.2 0.4 0.0013 19.1 0.2 2.6 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 PXF48116.1 - 0.00017 21.9 0.0 0.015 15.6 0.0 3.0 2 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PXF48116.1 - 0.00037 20.8 0.2 0.0015 18.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain PAP2 PF01569.21 PXF48117.1 - 5.7e-19 68.2 1.1 5.7e-19 68.2 1.1 2.3 1 1 1 2 2 2 1 PAP2 superfamily YobH PF13996.6 PXF48117.1 - 0.029 14.4 0.4 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 YobH-like protein PAP2_3 PF14378.6 PXF48117.1 - 2.6 7.7 11.7 18 4.9 11.7 2.5 1 1 0 1 1 1 0 PAP2 superfamily DUF1980 PF09323.10 PXF48118.1 - 0.01 15.8 0.8 0.01 15.8 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) NFACT-R_1 PF05670.13 PXF48120.1 - 1.6e-28 99.5 0.4 7.2e-28 97.4 0.0 2.2 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 PXF48120.1 - 6.1e-23 80.8 0.0 4.3e-22 78.0 0.0 2.6 1 0 0 1 1 1 1 NFACT protein C-terminal domain DUF5590 PF17881.1 PXF48120.1 - 0.0032 17.5 0.0 0.0098 16.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5590) DUF5374 PF17344.2 PXF48120.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5374) RNA_pol_Rpb2_6 PF00562.28 PXF48121.1 - 1.9e-104 349.8 0.0 2.8e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PXF48121.1 - 8.4e-29 100.5 0.0 1.3e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 PXF48121.1 - 2e-26 92.0 0.0 7.9e-26 90.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PXF48121.1 - 1.7e-19 70.0 0.0 4.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 PXF48121.1 - 5.7e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 PXF48121.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 PXF48121.1 - 0.00056 20.1 0.2 0.002 18.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_POL_M_15KD PF02150.16 PXF48121.1 - 0.036 13.9 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit VHL PF01847.16 PXF48121.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 VHL beta domain CBF PF03914.17 PXF48122.1 - 9.2e-39 133.2 0.0 9.2e-39 133.2 0.0 2.4 2 1 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 PXF48122.1 - 4e-05 23.7 5.6 0.00031 20.8 1.1 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TetR_C_8 PF14278.6 PXF48122.1 - 0.91 9.7 2.8 38 4.5 0.0 3.4 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region Sec34 PF04136.15 PXF48123.1 - 0.008 16.1 4.2 0.33 10.8 0.6 2.3 2 0 0 2 2 2 2 Sec34-like family WD40 PF00400.32 PXF48124.1 - 4.4e-09 36.8 10.5 0.0055 17.5 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48124.1 - 3.3e-07 30.5 0.0 0.46 10.8 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleotid_trans PF03407.16 PXF48125.1 - 2.3e-25 89.8 0.0 3.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TP6A_N PF04406.14 PXF48126.1 - 0.006 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 PXF48126.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) NUDIX PF00293.28 PXF48127.1 - 1.6e-13 50.9 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SAC3_GANP PF03399.16 PXF48128.1 - 1.6e-90 303.4 2.2 3.2e-90 302.5 2.2 1.5 1 0 0 1 1 1 1 SAC3/GANP family RRM_1 PF00076.22 PXF48128.1 - 0.0011 18.8 0.0 6.3 6.7 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.11 PXF48128.1 - 4.4 5.7 27.6 0.28 9.6 16.7 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein OKR_DC_1 PF01276.20 PXF48131.1 - 6.5e-62 209.6 0.0 2.5e-61 207.7 0.0 1.7 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 PXF48131.1 - 9.1e-08 32.5 0.0 2.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_1_2 PF00155.21 PXF48131.1 - 2.7e-07 30.1 0.1 3.9e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PXF48131.1 - 1.2e-06 27.7 0.9 1.8e-06 27.2 0.3 1.6 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PXF48131.1 - 0.00019 20.8 1.0 0.00031 20.2 1.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 PXF48131.1 - 0.00038 19.2 0.2 0.00056 18.6 0.2 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.20 PXF48131.1 - 0.0043 15.6 0.1 0.0067 15.0 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GATase_6 PF13522.6 PXF48131.1 - 0.07 13.3 0.4 15 5.8 0.0 2.6 1 1 1 2 2 2 0 Glutamine amidotransferase domain Ribosomal_L11 PF00298.19 PXF48132.1 - 6.8e-28 97.0 0.0 1.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 PXF48132.1 - 3e-26 91.0 0.2 5.1e-26 90.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain SurE PF01975.17 PXF48133.1 - 9.8e-38 129.9 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_4 PF13439.6 PXF48133.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Peptidase_S24 PF00717.23 PXF48134.1 - 2.1e-09 37.2 0.3 3.5e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like SufE PF02657.15 PXF48135.1 - 4e-35 120.3 0.0 5.9e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 PXF48135.1 - 1.8e-28 98.6 0.2 3.2e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 BolA-like protein An_peroxidase PF03098.15 PXF48136.1 - 1e-125 420.4 0.1 1.4e-125 419.9 0.1 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Pkinase PF00069.25 PXF48137.1 - 2.1e-76 256.8 0.0 3e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48137.1 - 3.9e-39 134.5 0.0 5.5e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF48137.1 - 3.6e-09 36.4 0.0 5.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF48137.1 - 0.0002 20.4 0.2 0.00035 19.6 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PXF48137.1 - 0.00024 20.8 0.2 0.00043 19.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PXF48137.1 - 0.0003 20.8 0.3 0.015 15.3 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF48137.1 - 0.055 12.8 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PXF48137.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 PXF48137.1 - 0.26 10.3 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cpn60_TCP1 PF00118.24 PXF48139.1 - 7.5e-145 483.3 12.4 8.5e-145 483.1 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 PXF48139.1 - 0.013 15.4 1.9 0.039 13.9 0.1 2.5 3 0 0 3 3 3 0 MftR C-terminal domain C2 PF00168.30 PXF48140.1 - 3.2e-09 37.0 0.0 1.1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain PGAP1 PF07819.13 PXF48140.1 - 0.0084 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 PXF48140.1 - 0.04 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase zf-C3HC4_3 PF13920.6 PXF48141.1 - 6.3e-14 51.6 12.4 9.8e-14 50.9 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF48141.1 - 7.7e-05 22.9 12.9 0.00013 22.2 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PXF48141.1 - 0.00032 20.5 12.7 0.0006 19.6 12.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PXF48141.1 - 0.0027 17.5 14.4 0.0048 16.7 14.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF48141.1 - 0.0028 17.6 12.8 0.0047 16.8 12.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.14 PXF48141.1 - 0.44 10.2 8.7 0.86 9.3 8.7 1.5 1 0 0 1 1 1 0 P-11 zinc finger XG_FTase PF03254.13 PXF48142.1 - 4.3e-06 25.6 0.0 0.0017 17.1 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.11 PXF48142.1 - 0.00035 19.5 0.0 0.0039 16.0 0.0 2.4 3 0 0 3 3 3 1 Nodulation protein Z (NodZ) DUF2046 PF09755.9 PXF48143.1 - 0.0075 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) SOGA PF11365.8 PXF48143.1 - 0.054 14.6 2.3 0.12 13.5 2.3 1.6 1 0 0 1 1 1 0 Protein SOGA DUF5102 PF17104.5 PXF48143.1 - 0.064 13.3 5.5 0.12 12.3 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) BRE1 PF08647.11 PXF48143.1 - 2.5 8.2 9.4 0.13 12.4 3.7 1.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Glycos_transf_1 PF00534.20 PXF48145.1 - 1.2e-15 57.5 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF48145.1 - 5.7e-12 46.2 0.0 9.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PXF48145.1 - 5.1e-06 26.8 0.0 2.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 CDC50 PF03381.15 PXF48146.1 - 5.2e-70 236.1 0.3 5.2e-70 236.1 0.3 2.1 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family EMP24_GP25L PF01105.24 PXF48147.1 - 2.2e-32 112.5 0.0 3.5e-32 111.8 0.0 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CLZ PF16526.5 PXF48147.1 - 0.055 13.8 0.4 0.097 13.0 0.4 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRCT_2 PF16589.5 PXF48148.1 - 0.00019 21.8 0.0 0.05 14.0 0.0 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain E1-E2_ATPase PF00122.20 PXF48149.1 - 4.1e-51 173.1 2.4 4.1e-51 173.1 2.4 3.0 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 PXF48149.1 - 2e-46 158.0 6.9 2e-46 158.0 6.9 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PXF48149.1 - 5.4e-23 82.4 1.7 3.4e-22 79.8 1.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PXF48149.1 - 9.7e-21 73.7 0.0 1.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PXF48149.1 - 2.1e-17 62.5 3.5 1.2e-16 60.1 0.1 3.4 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PXF48149.1 - 4.2e-06 26.7 0.6 1.7e-05 24.7 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF48149.1 - 1e-05 26.0 0.1 7.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ras PF00071.22 PXF48150.1 - 7e-49 165.5 0.0 8.4e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF48150.1 - 6.4e-30 103.8 0.0 9.7e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF48150.1 - 9.7e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PXF48150.1 - 3.6e-05 23.8 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 PXF48150.1 - 0.00076 19.8 0.1 0.013 15.9 0.2 2.4 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 PXF48150.1 - 0.0013 18.7 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PXF48150.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PXF48150.1 - 0.0063 15.7 0.7 1.7 7.7 0.0 2.8 2 1 1 3 3 3 1 G-protein alpha subunit AAA_7 PF12775.7 PXF48150.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 PXF48150.1 - 0.05 13.3 0.1 0.095 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PXF48150.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PXF48150.1 - 0.098 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 PXF48150.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 PXF48150.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 PXF48150.1 - 0.18 11.5 0.2 12 5.6 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 PXF48150.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 PXF48150.1 - 0.2 11.8 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M13_N PF05649.13 PXF48151.1 - 2.3e-79 267.8 0.2 2.9e-79 267.5 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 PXF48151.1 - 5.7e-69 231.8 0.0 1.3e-68 230.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 HMG_box PF00505.19 PXF48154.1 - 5.5e-28 97.2 39.6 1.8e-17 63.5 0.7 5.6 4 2 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 PXF48154.1 - 1.8e-24 86.1 33.1 8.5e-13 48.7 2.1 4.6 3 1 1 4 4 4 3 HMG-box domain DUF3106 PF11304.8 PXF48154.1 - 8.4 6.9 40.8 0.06 13.8 12.5 4.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3106) HMG_box_5 PF14887.6 PXF48154.1 - 8.5 6.4 30.2 0.33 10.9 2.5 4.5 2 2 2 4 4 4 0 HMG (high mobility group) box 5 zf-C2H2_jaz PF12171.8 PXF48155.1 - 0.0023 18.2 0.6 0.0023 18.2 0.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding ARS2 PF04959.13 PXF48155.1 - 0.0056 17.1 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 PXF48155.1 - 0.0059 17.4 2.3 0.04 14.8 2.3 2.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF48155.1 - 0.034 14.6 1.9 0.034 14.6 1.9 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 PXF48155.1 - 0.078 13.4 0.7 0.24 11.9 0.7 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type HMGL-like PF00682.19 PXF48156.1 - 4.9e-54 183.6 0.1 5.7e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 HMGL-like RRP7 PF12923.7 PXF48157.1 - 2.8e-16 59.7 6.5 5.4e-16 58.8 6.5 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Nitrate_red_del PF02613.15 PXF48157.1 - 0.005 16.8 0.0 0.032 14.3 0.0 2.2 1 1 0 1 1 1 1 Nitrate reductase delta subunit DUF5093 PF17011.5 PXF48157.1 - 0.011 16.1 0.6 0.022 15.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Arm PF00514.23 PXF48158.1 - 0.00044 20.2 0.4 1.8 8.7 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat TetR_C_12 PF16914.5 PXF48158.1 - 0.073 13.2 2.6 6 7.0 0.2 3.0 2 1 0 2 2 2 0 Bacterial transcriptional repressor C-terminal DUF5134 PF17197.4 PXF48159.1 - 1.2 9.1 6.4 0.066 13.1 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) ABC_tran PF00005.27 PXF48160.1 - 1.7e-35 122.5 0.0 5.1e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 PXF48160.1 - 2.7e-30 106.0 5.6 3.5e-30 105.6 5.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PXF48160.1 - 0.00021 20.8 0.4 0.018 14.5 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PXF48160.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PXF48160.1 - 0.0099 16.3 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 PXF48160.1 - 0.043 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 PXF48160.1 - 0.044 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PXF48160.1 - 0.085 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PXF48160.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 PXF48160.1 - 0.12 12.1 0.5 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 PXF48160.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase LRR_8 PF13855.6 PXF48161.1 - 1e-15 57.2 29.8 4.5e-09 35.9 1.7 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PXF48161.1 - 3.8e-11 43.0 12.3 0.00013 22.2 0.3 4.1 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PXF48161.1 - 7.2e-06 25.6 1.9 3.7e-05 23.3 1.5 2.0 1 1 1 2 2 2 2 Leucine-rich repeat DUF460 PF04312.13 PXF48161.1 - 0.07 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Tetraspanin PF00335.20 PXF48162.1 - 4.1e-05 23.4 10.7 5.5e-05 23.0 10.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Rib_5-P_isom_A PF06026.14 PXF48163.1 - 4.3e-07 29.7 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Pterin_4a PF01329.19 PXF48163.1 - 0.068 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Ribonuc_red_sm PF00268.21 PXF48164.1 - 6.7e-116 386.6 0.1 8.3e-116 386.3 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain BOP1NT PF08145.12 PXF48166.1 - 5.4e-65 219.9 13.4 5.4e-65 219.9 13.4 1.6 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 PXF48166.1 - 5.1e-16 58.8 8.2 2.8e-05 24.8 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48166.1 - 6e-06 26.5 0.3 5.1 7.5 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 PXF48169.1 - 7.2e-71 238.6 0.0 9e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48169.1 - 2.7e-43 148.1 0.0 3.5e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF48169.1 - 3.2e-08 33.2 0.0 6.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF48169.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PXF48169.1 - 0.0002 20.4 0.1 0.00063 18.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PXF48169.1 - 0.0012 18.9 2.9 0.0095 15.9 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 PXF48169.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PXF48169.1 - 0.025 14.2 0.2 0.042 13.4 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 PXF48169.1 - 0.047 12.7 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 PXF48169.1 - 0.091 11.5 3.6 0.44 9.3 3.6 2.1 1 1 0 1 1 1 0 Fungal protein kinase SR-25 PF10500.9 PXF48169.1 - 1.1 8.8 14.4 1.7 8.2 14.4 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_membrane_2 PF06472.15 PXF48170.1 - 7.3e-59 199.4 7.5 9.8e-59 199.0 7.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF48170.1 - 3.3e-19 69.8 0.0 6.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 PXF48170.1 - 1.1e-14 54.6 7.2 5.1e-14 52.4 7.2 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_30 PF13604.6 PXF48170.1 - 7.3e-05 22.6 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF48170.1 - 0.00038 20.9 1.0 0.00089 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 PXF48170.1 - 0.0016 18.3 0.1 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PXF48170.1 - 0.0026 17.4 0.0 0.0075 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF48170.1 - 0.016 15.7 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PXF48170.1 - 0.034 13.6 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 PXF48170.1 - 0.043 13.4 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PXF48170.1 - 0.049 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 PXF48170.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_membrane PF00664.23 PXF48170.1 - 0.072 12.7 12.2 0.13 11.9 12.2 1.4 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_7 PF12775.7 PXF48170.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PXF48170.1 - 0.074 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 PXF48170.1 - 0.076 13.3 0.1 0.29 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 PXF48170.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 PXF48170.1 - 0.13 11.9 0.0 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 PXF48170.1 - 0.16 11.3 0.1 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family E2F_TDP PF02319.20 PXF48172.1 - 3.5e-18 65.4 0.0 5.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 PXF48172.1 - 1e-12 48.2 1.6 2.5e-10 40.4 1.6 2.7 1 1 0 1 1 1 1 Transcription factor DP DUF899 PF05988.12 PXF48172.1 - 0.024 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) WD40 PF00400.32 PXF48173.1 - 7.5e-23 80.4 16.9 2e-06 28.4 0.3 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48173.1 - 2.6e-16 59.7 4.4 3.6e-06 27.2 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF48173.1 - 5.2e-06 26.5 0.5 0.00052 20.0 0.2 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PXF48173.1 - 3e-05 23.1 1.8 0.02 13.8 0.8 3.9 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF48173.1 - 0.0017 17.1 2.5 0.047 12.3 0.5 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PSII_BNR PF14870.6 PXF48173.1 - 0.0049 16.2 0.1 0.0083 15.4 0.1 1.3 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Drc1-Sld2 PF11719.8 PXF48174.1 - 0.03 13.9 0.7 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 DNA replication and checkpoint protein PVL_ORF50 PF07768.11 PXF48174.1 - 0.047 14.0 2.0 0.071 13.4 2.0 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family DUF1823 PF08853.11 PXF48175.1 - 1.2e-30 106.0 0.1 1.5e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1823) Metallophos PF00149.28 PXF48176.1 - 2.5e-11 44.5 0.1 3.6e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PXF48176.1 - 6.1e-07 29.8 0.4 4.7e-05 23.6 0.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LID PF17916.1 PXF48176.1 - 0.07 12.8 3.4 5.9 6.6 0.1 3.2 2 1 1 3 3 3 0 LIM interaction domain (LID) TOM20_plant PF06552.12 PXF48177.1 - 0.042 13.6 0.1 4.3 7.0 0.0 2.6 1 1 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 ERO1 PF04137.15 PXF48177.1 - 0.064 12.4 1.8 0.14 11.3 1.8 1.6 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PIN_9 PF18477.1 PXF48177.1 - 0.51 10.7 7.1 1.4 9.2 0.2 2.7 1 1 1 2 2 2 0 PIN like domain Tropomyosin PF00261.20 PXF48177.1 - 0.87 8.9 35.5 0.0064 15.9 26.0 2.1 2 0 0 2 2 2 0 Tropomyosin DUF4801 PF16059.5 PXF48178.1 - 0.88 9.6 7.4 0.085 12.8 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4801) BAR PF03114.18 PXF48179.1 - 0.0043 16.7 7.6 0.013 15.2 7.6 1.6 1 1 0 1 1 1 1 BAR domain HOOK PF05622.12 PXF48179.1 - 0.028 12.6 5.9 0.012 13.8 2.5 1.7 2 0 0 2 2 2 0 HOOK protein TPR_MLP1_2 PF07926.12 PXF48179.1 - 0.032 14.3 5.2 1.6 8.8 1.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DegS PF05384.11 PXF48179.1 - 0.033 13.7 2.4 0.62 9.5 0.0 2.8 1 1 0 2 2 2 0 Sensor protein DegS DUF2884 PF11101.8 PXF48179.1 - 0.035 13.6 0.1 0.059 12.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Mod_r PF07200.13 PXF48179.1 - 0.035 14.2 2.3 0.67 10.1 0.5 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 PXF48179.1 - 0.06 12.2 1.3 0.075 11.9 1.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prp19 PF08606.11 PXF48179.1 - 0.089 12.8 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Prp19/Pso4-like V_ATPase_I PF01496.19 PXF48179.1 - 0.12 10.3 0.3 0.15 9.9 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T3SSipB PF16535.5 PXF48179.1 - 0.12 12.9 5.9 4.5 7.7 0.8 2.2 1 1 0 2 2 2 0 Type III cell invasion protein SipB DUF3502 PF12010.8 PXF48179.1 - 0.15 12.7 1.8 0.54 10.9 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3502) CLZ PF16526.5 PXF48179.1 - 0.27 11.6 1.6 1.8 9.0 0.0 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GrpE PF01025.19 PXF48179.1 - 0.32 10.6 0.1 0.32 10.6 0.1 2.2 2 1 0 2 2 2 0 GrpE PRKG1_interact PF15898.5 PXF48179.1 - 0.37 11.7 4.5 3.9 8.4 0.1 2.5 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain XhlA PF10779.9 PXF48179.1 - 0.45 10.7 4.3 69 3.8 0.1 3.3 2 1 1 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 PXF48179.1 - 0.52 10.5 2.7 0.85 9.8 0.4 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 PXF48179.1 - 0.74 10.3 5.8 5.9 7.4 3.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2408 PF10303.9 PXF48179.1 - 0.89 10.1 3.4 2.7 8.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) CHCH PF06747.13 PXF48180.1 - 2.6e-06 27.4 2.3 5.1e-06 26.5 2.2 1.6 1 1 1 2 2 2 1 CHCH domain NDUF_B7 PF05676.13 PXF48180.1 - 6.1e-05 22.7 0.8 8.5e-05 22.2 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 PXF48180.1 - 0.0032 17.5 2.0 0.0059 16.6 2.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 PXF48180.1 - 0.034 14.4 3.8 0.092 13.1 3.8 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 MTCP1 PF08991.10 PXF48180.1 - 0.12 12.6 3.2 0.18 12.1 3.2 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type ADH_zinc_N PF00107.26 PXF48181.1 - 8.4e-26 90.5 0.1 1.4e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PXF48181.1 - 1.3e-14 55.4 0.0 2.8e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PXF48181.1 - 0.00041 19.9 0.1 0.00059 19.4 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 PXF48181.1 - 0.00059 19.7 0.0 0.046 13.6 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Cyt-b5 PF00173.28 PXF48183.1 - 1.4e-21 76.4 0.0 2.1e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rhomboid PF01694.22 PXF48184.1 - 1.8e-21 76.7 19.0 2.7e-21 76.2 19.0 1.3 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 PXF48184.1 - 6.5e-08 32.7 11.9 1e-07 32.1 11.9 1.3 1 0 0 1 1 1 1 Der1-like family MTS PF05175.14 PXF48185.1 - 1.8e-14 53.6 1.1 1.1e-13 51.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PXF48185.1 - 8.8e-14 51.6 0.1 1.6e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PXF48185.1 - 2.4e-12 46.9 0.6 4.3e-12 46.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PXF48185.1 - 4.7e-12 46.5 0.3 1.1e-11 45.3 0.3 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF48185.1 - 2.9e-10 40.7 0.1 7.2e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PXF48185.1 - 1.3e-07 31.4 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 bZIP_1 PF00170.21 PXF48185.1 - 1.4e-07 31.5 10.5 1.4e-07 31.5 10.5 2.0 2 0 0 2 2 1 1 bZIP transcription factor UPF0020 PF01170.18 PXF48185.1 - 5.7e-07 29.4 3.0 2e-06 27.7 0.4 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 bZIP_2 PF07716.15 PXF48185.1 - 1.1e-05 25.4 9.5 3e-05 24.0 9.5 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Methyltransf_12 PF08242.12 PXF48185.1 - 7.8e-05 23.3 0.0 0.00017 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF48185.1 - 8.9e-05 21.9 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 PXF48185.1 - 0.0001 22.3 0.3 0.00018 21.5 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PXF48185.1 - 0.00014 21.9 0.2 0.00014 21.9 0.2 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF48185.1 - 0.00079 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PXF48185.1 - 0.00099 18.9 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein N6_Mtase PF02384.16 PXF48185.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_24 PF13578.6 PXF48185.1 - 0.0064 17.5 0.0 0.017 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PXF48185.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_10 PF05971.12 PXF48185.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase PCMT PF01135.19 PXF48185.1 - 0.03 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.8 PXF48185.1 - 0.046 13.2 0.8 0.5 9.8 0.3 2.2 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_15 PF09445.10 PXF48185.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase N6-adenineMlase PF10237.9 PXF48185.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_9 PF08003.11 PXF48185.1 - 0.1 11.5 1.1 0.12 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) CMAS PF02353.20 PXF48185.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTBP_C PF14920.6 PXF48185.1 - 0.91 9.2 11.3 1.4 8.6 11.3 1.3 1 0 0 1 1 1 0 MDM2-binding MgtC PF02308.16 PXF48186.1 - 1.4e-26 93.2 14.1 1.4e-26 93.2 14.1 1.6 2 0 0 2 2 2 1 MgtC family Anophelin PF10731.9 PXF48186.1 - 0.54 10.1 0.1 0.54 10.1 0.1 2.0 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito MgtC PF02308.16 PXF48187.1 - 2.7e-08 34.2 12.7 5.2e-08 33.3 12.7 1.4 1 0 0 1 1 1 1 MgtC family ABC2_membrane_5 PF13346.6 PXF48187.1 - 0.26 10.8 4.1 0.45 10.0 4.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein TPR_MLP1_2 PF07926.12 PXF48188.1 - 5.4e-05 23.3 10.3 0.003 17.6 4.7 2.3 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PXF48188.1 - 0.002 17.5 2.1 0.002 17.5 2.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF3456 PF11938.8 PXF48188.1 - 0.0059 17.1 4.3 0.011 16.2 3.6 1.9 1 1 1 2 2 2 1 TLR4 regulator and MIR-interacting MSAP Tropomyosin PF00261.20 PXF48188.1 - 0.038 13.4 10.7 0.048 13.0 5.0 2.8 2 1 1 3 3 3 0 Tropomyosin TMF_TATA_bd PF12325.8 PXF48188.1 - 0.18 12.0 4.5 0.71 10.1 3.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 PXF48188.1 - 0.18 12.0 6.0 6.6 7.1 1.7 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Cytochrom_B562 PF07361.11 PXF48188.1 - 0.4 11.4 5.6 13 6.5 3.6 2.6 2 1 0 2 2 2 0 Cytochrome b562 BAR PF03114.18 PXF48188.1 - 0.46 10.1 7.2 0.95 9.1 7.2 1.6 1 1 0 1 1 1 0 BAR domain HalX PF08663.10 PXF48188.1 - 0.94 9.8 7.7 13 6.2 0.3 2.6 2 0 0 2 2 2 0 HalX domain InPase PF18823.1 PXF48188.1 - 1.1 9.0 5.8 1.4 8.6 0.5 2.7 3 0 0 3 3 3 0 Inorganic Pyrophosphatase TBCA PF02970.16 PXF48188.1 - 4.8 7.6 11.2 0.8 10.1 5.1 2.6 3 0 0 3 3 3 0 Tubulin binding cofactor A RRM_3 PF08777.11 PXF48189.1 - 1.9e-27 95.3 0.1 1.9e-27 95.3 0.1 2.7 2 1 0 2 2 2 1 RNA binding motif La PF05383.17 PXF48189.1 - 1.8e-22 79.2 0.1 4.4e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 PXF48189.1 - 3e-09 36.6 0.0 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldose_epim PF01263.20 PXF48190.1 - 1.7e-38 132.7 0.0 2.3e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase RNA_pol_Rpb6 PF01192.22 PXF48191.1 - 4.5e-17 61.7 0.2 7.5e-17 61.0 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 DEAD PF00270.29 PXF48192.1 - 7e-42 143.2 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48192.1 - 8.6e-19 67.9 0.0 3.8e-18 65.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PXF48192.1 - 4.6e-14 52.4 0.1 1.1e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PXF48192.1 - 8.4e-09 35.7 0.0 4.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit 3Beta_HSD PF01073.19 PXF48193.1 - 1e-67 228.1 0.0 1.3e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PXF48193.1 - 1.1e-35 123.3 0.0 1.4e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF48193.1 - 6e-21 75.2 0.0 3.3e-17 62.9 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PXF48193.1 - 1e-20 74.0 0.0 9e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PXF48193.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PXF48193.1 - 1.7e-15 57.4 0.0 2.3e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 PXF48193.1 - 3e-11 43.0 0.1 6e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 PXF48193.1 - 0.00047 20.1 0.1 0.0016 18.4 0.1 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 PXF48193.1 - 0.033 13.7 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family WD40 PF00400.32 PXF48194.1 - 1.4e-24 85.9 19.6 1e-05 26.2 0.0 11.0 11 1 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48194.1 - 8e-08 32.5 1.1 0.45 10.9 0.0 6.8 5 2 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PXF48194.1 - 0.0095 16.0 0.2 8.3 6.5 0.0 5.0 7 0 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 PXF48194.1 - 0.014 14.2 0.5 4.5 5.9 0.0 2.8 3 0 0 3 3 3 0 Nup133 N terminal like Kelch_4 PF13418.6 PXF48194.1 - 0.025 14.6 0.1 0.28 11.2 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain WD40_like PF17005.5 PXF48194.1 - 0.37 10.1 2.2 10 5.4 0.2 2.9 4 0 0 4 4 4 0 WD40-like domain Porphobil_deam PF01379.20 PXF48195.1 - 1.8e-74 249.6 0.1 2.4e-74 249.2 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 PXF48195.1 - 2e-16 60.1 0.1 3.7e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SBP_bac_3 PF00497.20 PXF48195.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 RWD PF05773.22 PXF48198.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 PXF48198.1 - 5.1e-08 33.3 2.3 5.1e-08 33.3 2.3 1.9 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Hydantoinase_B PF02538.14 PXF48199.1 - 1.1e-207 690.6 0.4 1.5e-207 690.1 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PXF48199.1 - 8.9e-102 340.3 0.0 2.5e-101 338.8 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PXF48199.1 - 1.7e-52 177.7 1.0 1.1e-50 171.8 0.1 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF896 PF05979.12 PXF48199.1 - 0.14 12.1 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) OTU PF02338.19 PXF48202.1 - 4.9e-21 75.5 0.0 9.9e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PXF48202.1 - 2.5e-07 30.4 0.0 0.00023 20.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF2203 PF09969.9 PXF48202.1 - 8.8 7.1 10.2 11 6.8 1.2 2.5 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) MitMem_reg PF13012.6 PXF48203.1 - 2.4e-24 85.9 0.0 3.7e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PXF48203.1 - 1.9e-15 56.9 0.0 4.1e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.31 PXF48204.1 - 0.0012 19.0 0.1 0.0024 18.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 PXF48204.1 - 0.0025 17.8 0.4 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 PXF48204.1 - 0.4 10.8 3.1 0.99 9.6 0.3 2.4 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain TLC PF03219.14 PXF48205.1 - 1.3e-191 637.7 12.9 1.6e-191 637.3 12.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF3784 PF12650.7 PXF48205.1 - 0.0087 16.2 1.2 0.0087 16.2 1.2 4.7 5 2 2 7 7 7 1 Domain of unknown function (DUF3784) Peptidase_S9 PF00326.21 PXF48206.1 - 1.3e-24 86.8 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PXF48206.1 - 2.4e-09 37.2 0.0 6.7e-07 29.2 0.0 2.3 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PXF48206.1 - 0.0029 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 PXF48206.1 - 0.0032 17.0 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 PXF48206.1 - 0.012 14.9 0.0 0.28 10.4 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PXF48206.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PD40 PF07676.12 PXF48206.1 - 0.028 14.3 2.4 0.13 12.2 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 PXF48206.1 - 0.084 13.5 0.0 0.084 13.5 0.0 3.4 3 1 0 4 4 4 0 Alpha/beta hydrolase family Metallophos PF00149.28 PXF48207.1 - 5.9e-12 46.5 0.0 8.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.13 PXF48207.1 - 1.5e-11 44.9 0.0 3.9e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.7 PXF48207.1 - 6.3e-05 23.2 0.0 0.00013 22.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_transf_4 PF13439.6 PXF48207.1 - 0.0064 16.5 0.2 4.2 7.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 WD40 PF00400.32 PXF48209.1 - 4.5e-16 58.9 7.9 2.1e-06 28.3 0.7 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48209.1 - 4.6e-06 26.8 0.0 0.11 12.8 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L10 PF00466.20 PXF48210.1 - 1.5e-17 63.5 1.3 2.2e-17 63.0 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_L7Ae PF01248.26 PXF48211.1 - 2.8e-11 43.0 0.0 6.8e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PXF48211.1 - 2.8e-07 30.7 0.0 4.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 Cullin PF00888.22 PXF48212.1 - 1.2e-21 77.0 2.2 1.7e-21 76.5 0.7 1.9 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 PXF48212.1 - 1.5e-19 70.2 0.5 6.6e-19 68.2 0.5 2.2 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 HTH_9 PF08221.11 PXF48212.1 - 0.017 15.2 1.2 1.2 9.3 0.0 4.0 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain NDUF_B7 PF05676.13 PXF48213.1 - 1e-27 95.7 8.6 1.3e-27 95.3 8.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) 2-oxoacid_dh PF00198.23 PXF48214.1 - 2.5e-82 275.8 0.0 3.1e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PXF48214.1 - 1e-12 47.7 0.7 2.1e-12 46.7 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PXF48214.1 - 6.3e-10 39.2 0.6 1.3e-09 38.3 0.6 1.6 1 0 0 1 1 1 1 e3 binding domain MAGE_N PF12440.8 PXF48214.1 - 0.041 14.6 4.1 0.087 13.5 4.1 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal RuBisCo_chap_C PF18087.1 PXF48215.1 - 2.5e-10 40.1 0.0 3.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain NAD_binding_6 PF08030.12 PXF48216.1 - 1.1e-16 61.3 0.0 4.1e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PXF48216.1 - 2.3e-14 53.6 8.2 2.3e-14 53.6 8.2 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PXF48216.1 - 5.8e-14 52.1 0.0 1.8e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 PXF48216.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Peptidase_M75 PF09375.10 PXF48217.1 - 2.1e-26 93.0 2.6 1.3e-15 57.7 0.0 2.9 2 2 0 2 2 2 2 Imelysin Chloroa_b-bind PF00504.21 PXF48218.1 - 0.00035 21.1 0.1 0.098 13.2 0.0 1.3 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Cu-oxidase_2 PF07731.14 PXF48219.1 - 8.6e-06 25.5 1.0 6.1e-05 22.8 1.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase Peptidase_M75 PF09375.10 PXF48222.1 - 2.7e-26 92.7 2.6 1.6e-15 57.4 0.0 2.9 2 2 0 2 2 2 2 Imelysin Ephrin_rec_like PF07699.13 PXF48223.1 - 9e-21 73.4 93.2 6.4e-07 29.0 13.0 9.9 2 2 8 10 10 10 9 Putative ephrin-receptor like NCD3G PF07562.14 PXF48223.1 - 1.7e-08 34.3 71.2 0.025 14.5 2.3 8.6 2 1 5 10 10 10 10 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PXF48223.1 - 0.0027 18.1 83.0 0.099 13.1 1.8 11.7 4 3 6 11 11 11 8 TNFR/NGFR cysteine-rich region Ribosomal_L37ae PF01780.19 PXF48223.1 - 3.3 7.9 5.2 5.2 7.2 0.3 3.0 3 0 0 3 3 3 0 Ribosomal L37ae protein family Rad60-SLD PF11976.8 PXF48224.1 - 2e-21 75.6 0.1 2.4e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PXF48224.1 - 1.7e-08 34.1 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.12 PXF48224.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) MMS1_N PF10433.9 PXF48225.1 - 1.1e-27 96.8 0.0 2.4e-21 76.0 0.0 3.4 3 1 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PXF48225.1 - 2.2e-19 70.0 0.0 3.6e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region RRM_1 PF00076.22 PXF48226.1 - 5.2e-11 42.2 0.0 8.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 PXF48227.1 - 1.1e-40 139.2 0.0 1.9e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48227.1 - 1.6e-30 105.7 0.0 3.7e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 PXF48227.1 - 0.01 15.9 2.3 0.016 15.2 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ResIII PF04851.15 PXF48227.1 - 0.09 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cyclin PF08613.11 PXF48228.1 - 3.5e-15 56.7 0.2 4.8e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF48228.1 - 5.7e-09 35.8 2.2 9.6e-09 35.1 2.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spy1 PF11357.8 PXF48228.1 - 0.037 14.3 0.4 0.06 13.6 0.4 1.3 1 0 0 1 1 1 0 Cell cycle regulatory protein bZIP_1 PF00170.21 PXF48229.1 - 9.2e-08 32.1 14.1 9.2e-08 32.1 14.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF4559 PF15112.6 PXF48229.1 - 0.028 14.1 9.9 0.042 13.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) She9_MDM33 PF05546.11 PXF48229.1 - 0.26 11.1 10.9 0.4 10.4 10.9 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family bZIP_2 PF07716.15 PXF48229.1 - 0.38 10.9 25.0 0.063 13.4 13.9 2.8 1 1 1 2 2 2 0 Basic region leucine zipper PKcGMP_CC PF16808.5 PXF48229.1 - 1.1 9.2 12.1 0.06 13.2 4.3 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Jnk-SapK_ap_N PF09744.9 PXF48229.1 - 1.3 9.3 15.4 2.2 8.5 15.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Pox_G5 PF04599.12 PXF48229.1 - 1.8 7.5 7.1 2.5 7.0 7.1 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Exonuc_VII_L PF02601.15 PXF48229.1 - 2.6 7.5 11.3 4 6.9 11.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GBP_C PF02841.14 PXF48229.1 - 3.8 6.8 15.0 5.9 6.2 15.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Draxin PF15550.6 PXF48229.1 - 5 6.9 11.0 12 5.7 11.0 1.6 1 0 0 1 1 1 0 Draxin AAA_23 PF13476.6 PXF48229.1 - 6.2 7.3 8.5 8.9 6.8 8.5 1.2 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 PXF48229.1 - 8.2 4.9 8.8 11 4.5 8.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 PXF48229.1 - 9 6.2 7.3 16 5.3 7.3 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FAD_binding_4 PF01565.23 PXF48230.1 - 5.4e-24 84.5 0.1 2.3e-23 82.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 PXF48230.1 - 1.1e-13 51.0 1.1 1.1e-13 51.0 1.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like DUF465 PF04325.13 PXF48231.1 - 0.054 13.5 0.7 0.087 12.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF465) Atg14 PF10186.9 PXF48232.1 - 1.5 7.8 8.5 2 7.4 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Band_7 PF01145.25 PXF48233.1 - 5.1e-09 36.4 19.4 1e-06 28.9 19.4 3.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family Flot PF15975.5 PXF48233.1 - 0.0025 18.0 1.9 0.0025 18.0 1.9 4.8 1 1 3 4 4 4 2 Flotillin ALMT PF11744.8 PXF48233.1 - 0.96 8.2 11.7 1.4 7.7 11.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter ATC_hydrolase PF14196.6 PXF48237.1 - 1.6e-10 41.9 0.4 3.4e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase AAA PF00004.29 PXF48238.1 - 1.4e-43 148.5 0.1 3.4e-43 147.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF48238.1 - 1.8e-10 40.5 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PXF48238.1 - 2.4e-08 33.8 0.3 2.2e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 PXF48238.1 - 9.7e-08 32.1 0.1 3.1e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PXF48238.1 - 4.4e-07 30.2 0.1 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PXF48238.1 - 9.6e-07 29.3 0.1 0.00025 21.5 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 PXF48238.1 - 4.3e-06 26.1 0.1 1.5e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 PXF48238.1 - 8.7e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF48238.1 - 0.0002 21.6 0.8 0.026 14.8 0.8 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PXF48238.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PXF48238.1 - 0.00041 20.9 0.0 0.0012 19.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 PXF48238.1 - 0.0006 19.9 0.1 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PXF48238.1 - 0.0037 17.6 0.0 0.0089 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 PXF48238.1 - 0.0046 17.1 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 PXF48238.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 PXF48238.1 - 0.0058 16.0 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PXF48238.1 - 0.0063 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 PXF48238.1 - 0.0076 16.3 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 PXF48238.1 - 0.0096 15.8 0.1 0.094 12.6 0.0 2.5 3 0 0 3 3 3 1 NTPase AAA_7 PF12775.7 PXF48238.1 - 0.013 15.0 0.2 0.1 12.1 0.2 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 PXF48238.1 - 0.017 15.0 0.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 PXF48238.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 PXF48238.1 - 0.026 14.2 0.3 0.062 13.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PXF48238.1 - 0.03 14.0 0.2 0.068 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PXF48238.1 - 0.031 13.8 1.0 0.096 12.3 1.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PXF48238.1 - 0.046 13.1 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 PXF48238.1 - 0.053 13.2 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 PXF48238.1 - 0.057 12.8 0.7 0.34 10.2 0.0 2.4 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 PXF48238.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 PXF48238.1 - 0.088 11.9 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 PXF48238.1 - 0.14 11.4 0.1 0.48 9.6 0.1 1.8 1 1 0 1 1 1 0 NB-ARC domain Proteasome PF00227.26 PXF48239.1 - 8.8e-57 191.7 0.1 1.2e-56 191.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PXF48239.1 - 2.4e-14 52.6 0.2 6.9e-14 51.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pantoate_ligase PF02569.15 PXF48240.1 - 1.5e-83 280.1 0.0 1.7e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Phage_Nu1 PF07471.12 PXF48241.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Hemerythrin PF01814.23 PXF48241.1 - 0.044 14.4 0.1 0.11 13.1 0.0 1.8 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Glyco_trans_1_4 PF13692.6 PXF48242.1 - 3.5e-07 30.7 0.0 8.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PXF48242.1 - 0.0047 16.5 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin PF00085.20 PXF48243.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin ATP12 PF07542.11 PXF48244.1 - 1.6e-25 89.7 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein HisG PF01634.18 PXF48244.1 - 0.031 14.2 0.2 0.13 12.2 0.1 1.8 1 1 1 2 2 2 0 ATP phosphoribosyltransferase RL10P_insert PF17777.1 PXF48244.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P PCO_ADO PF07847.12 PXF48245.1 - 3e-38 131.3 0.2 4.3e-38 130.8 0.2 1.2 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 PXF48245.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Cupin domain SHS2_Rpb7-N PF03876.17 PXF48246.1 - 1.3e-07 31.8 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 PXF48246.1 - 0.0014 19.2 0.0 0.0014 19.2 0.0 4.6 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I GCV_H PF01597.19 PXF48247.1 - 2.8e-44 149.9 0.1 3.2e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 PXF48247.1 - 0.048 13.5 0.4 0.17 11.7 0.2 2.0 2 1 1 3 3 3 0 Biotin-requiring enzyme Ist1 PF03398.14 PXF48248.1 - 2.4e-28 99.1 0.0 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Aminotran_1_2 PF00155.21 PXF48249.1 - 2.4e-53 181.6 0.0 2.8e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 PXF48249.1 - 0.00091 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_MocR PF12897.7 PXF48249.1 - 0.031 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase AA_permease_N PF08403.10 PXF48249.1 - 0.16 11.5 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Amino acid permease N-terminal TruD PF01142.18 PXF48250.1 - 6.5e-59 199.8 0.9 2e-54 185.0 0.0 3.5 4 0 0 4 4 4 3 tRNA pseudouridine synthase D (TruD) TetR_C_28 PF17937.1 PXF48250.1 - 0.12 12.8 0.2 0.39 11.2 0.2 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TrbE PF11100.8 PXF48251.1 - 0.041 14.1 0.3 0.18 12.0 0.3 2.1 1 0 0 1 1 1 0 Conjugal transfer protein TrbE SecD_SecF PF02355.16 PXF48251.1 - 0.081 12.3 1.4 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein export membrane protein Myb_DNA-binding PF00249.31 PXF48252.1 - 2.4e-30 104.4 2.7 3.3e-14 52.8 0.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF48252.1 - 1.4e-21 76.5 0.9 3.4e-13 49.6 0.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 PXF48252.1 - 6.2e-06 26.2 0.5 0.0041 17.1 0.0 3.0 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 PXF48252.1 - 2.5e-05 24.1 2.8 0.00014 21.7 0.0 2.7 2 1 1 3 3 3 1 Myb DNA-binding like SUIM_assoc PF16619.5 PXF48252.1 - 0.0019 18.2 2.7 0.0019 18.2 2.7 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PXF48252.1 - 0.007 16.0 5.3 0.011 15.4 5.3 1.4 1 0 0 1 1 1 1 Spt20 family SANT_DAMP1_like PF16282.5 PXF48252.1 - 0.023 14.9 0.1 7.3 6.9 0.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Bac_globin PF01152.21 PXF48252.1 - 0.23 11.6 1.3 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial-like globin Roughex PF06020.11 PXF48252.1 - 0.71 8.9 2.9 1.1 8.2 2.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Peptidase_M50 PF02163.22 PXF48253.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M50 Ku PF02735.16 PXF48253.1 - 0.18 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain Peptidase_M50B PF13398.6 PXF48253.1 - 0.69 9.5 5.5 0.29 10.8 0.4 2.2 1 1 1 2 2 2 0 Peptidase M50B-like GSHPx PF00255.19 PXF48254.1 - 1.8e-22 78.9 0.0 2.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DUF685 PF05085.12 PXF48254.1 - 0.024 14.0 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF685) Redoxin PF08534.10 PXF48254.1 - 0.029 14.1 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 PXF48254.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family HSP70 PF00012.20 PXF48255.1 - 1.2e-73 248.3 21.2 1.2e-71 241.8 21.2 2.3 1 1 0 1 1 1 1 Hsp70 protein NAM-associated PF14303.6 PXF48255.1 - 0.82 10.4 24.0 0.034 14.9 14.2 2.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Zip PF02535.22 PXF48255.1 - 3.4 6.8 4.3 6.1 6.0 4.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_trans_1_4 PF13692.6 PXF48257.1 - 1.5e-09 38.4 0.0 2.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PXF48257.1 - 3.5e-07 29.9 0.0 6.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PXF48257.1 - 0.00042 20.7 0.0 0.0015 18.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF48257.1 - 0.087 12.8 1.0 0.36 10.8 1.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Voltage_CLC PF00654.20 PXF48258.1 - 7.1e-59 199.8 28.0 7.1e-59 199.8 28.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PXF48258.1 - 0.00018 21.9 0.1 0.12 12.9 0.0 3.6 3 0 0 3 3 3 2 CBS domain PEMT PF04191.13 PXF48259.1 - 6.9e-43 145.4 17.4 8.7e-24 84.0 0.9 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase ATP-synt_E PF05680.12 PXF48260.1 - 1.1e-05 25.6 0.1 1.4e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 ATP synthase E chain PKcGMP_CC PF16808.5 PXF48260.1 - 0.0065 16.3 0.3 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Wtap PF17098.5 PXF48260.1 - 0.015 15.3 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family DivIC PF04977.15 PXF48260.1 - 0.056 13.2 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF5082 PF16888.5 PXF48260.1 - 0.058 13.7 1.5 0.074 13.3 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) His_Phos_1 PF00300.22 PXF48261.1 - 8.6e-14 51.7 0.1 7.4e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Quaking_NLS PF16551.5 PXF48262.1 - 0.2 11.4 0.2 0.38 10.5 0.2 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking Ribosomal_L1 PF00687.21 PXF48263.1 - 1.5e-42 145.7 0.0 1.9e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_4 PF13894.6 PXF48264.1 - 1.2e-12 47.5 10.7 0.00061 20.4 0.9 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF48264.1 - 5.5e-12 45.4 12.4 0.00033 20.9 0.2 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PXF48264.1 - 6.8e-06 26.2 1.0 0.76 10.1 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF48264.1 - 1.1e-05 25.7 5.6 0.71 10.3 0.5 3.3 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PXF48264.1 - 3e-05 23.9 9.3 0.029 14.4 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 PXF48264.1 - 0.00036 20.1 4.5 2.7 7.7 0.0 3.1 2 1 1 3 3 3 3 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 PXF48264.1 - 0.0012 19.5 2.2 0.037 14.7 0.2 2.5 2 1 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 PXF48264.1 - 0.0027 18.0 5.6 1.1 9.6 0.1 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 PXF48264.1 - 0.0062 17.2 2.0 0.028 15.1 2.0 2.1 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 PXF48264.1 - 0.0083 15.9 6.8 0.56 10.0 0.2 3.2 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 PXF48264.1 - 0.029 14.5 3.7 0.96 9.6 0.0 3.0 2 1 1 3 3 3 0 Zinc ribbon domain DUF2256 PF10013.9 PXF48264.1 - 0.077 13.1 4.5 12 6.1 0.5 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HalOD2 PF18547.1 PXF48264.1 - 0.084 12.8 0.8 0.084 12.8 0.8 1.8 2 1 0 2 2 2 0 Halobacterial output domain 2 zf-C2H2_9 PF16293.5 PXF48264.1 - 0.087 12.7 2.5 5.5 6.9 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 PXF48264.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger LRR_8 PF13855.6 PXF48265.1 - 4.9e-23 80.7 22.0 4.8e-07 29.5 0.4 4.3 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PXF48265.1 - 1.5e-19 69.8 17.0 8.5e-06 26.0 0.2 5.5 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PXF48265.1 - 0.00011 22.1 0.0 0.00037 20.5 0.0 1.6 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 PXF48265.1 - 0.0004 20.4 0.0 0.95 9.6 0.0 4.0 3 1 2 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 PXF48265.1 - 0.00045 20.4 13.4 14 6.7 0.1 6.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 PXF48265.1 - 0.0029 17.5 12.7 5.9 7.2 0.0 6.2 6 0 0 6 6 6 2 Leucine Rich repeat BTK PF00779.19 PXF48266.1 - 0.013 15.3 1.4 0.04 13.7 1.4 1.9 1 0 0 1 1 1 0 BTK motif tRNA-synt_1 PF00133.22 PXF48267.1 - 3e-200 666.5 0.0 3.3e-199 663.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PXF48267.1 - 2e-39 135.0 0.0 4e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PXF48267.1 - 1.5e-14 53.6 0.2 1.2e-05 24.3 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PXF48267.1 - 1.7e-06 27.7 6.2 3.8e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 PXF48267.1 - 0.0096 16.2 2.1 0.0096 16.2 2.1 3.2 4 0 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm Jag_N PF14804.6 PXF48267.1 - 0.041 14.2 0.2 0.15 12.5 0.2 2.0 1 0 0 1 1 1 0 Jag N-terminus tRNA-synt_1e PF01406.19 PXF48267.1 - 0.1 11.9 0.1 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF2992 PF11208.8 PXF48267.1 - 3.5 7.9 9.6 7.5 6.8 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Peptidase_S7 PF00949.21 PXF48268.1 - 0.14 12.0 0.5 1.9 8.3 0.0 2.3 2 1 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease TAF8_C PF10406.9 PXF48269.1 - 3.6e-10 40.2 0.1 3.6e-10 40.2 0.1 2.5 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 PXF48269.1 - 1.1e-08 35.0 0.3 2.2e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 Bromodomain associated CENP-S PF15630.6 PXF48269.1 - 0.00028 21.2 3.3 0.00053 20.3 0.1 2.7 2 1 1 3 3 3 1 CENP-S protein EspB PF05802.11 PXF48269.1 - 0.0036 17.3 1.4 0.0036 17.3 1.4 2.2 2 1 0 2 2 2 1 Enterobacterial EspB protein CENP-T_C PF15511.6 PXF48269.1 - 0.0036 17.4 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 PXF48269.1 - 0.016 15.3 0.6 0.037 14.1 0.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 PXF48269.1 - 0.026 14.8 0.2 0.094 13.0 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PXF48269.1 - 0.031 14.6 0.0 0.031 14.6 0.0 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Latrotoxin_C PF15658.6 PXF48269.1 - 0.13 12.0 0.1 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Latrotoxin C-terminal domain DUF3042 PF11240.8 PXF48271.1 - 0.0052 16.8 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3042) Reprolysin_2 PF13574.6 PXF48271.1 - 0.031 14.2 0.1 0.063 13.2 0.0 1.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like GDA1_CD39 PF01150.17 PXF48272.1 - 7.1e-44 150.1 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNase_H2-Ydr279 PF09468.10 PXF48273.1 - 2.5e-07 31.0 2.5 8.1e-07 29.4 2.3 2.0 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF3622 PF12286.8 PXF48273.1 - 0.044 14.1 1.9 0.097 13.0 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) WXG100 PF06013.12 PXF48274.1 - 0.0064 16.7 0.1 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG DUF1940 PF09155.10 PXF48274.1 - 0.048 13.8 0.3 0.09 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) NAM-associated PF14303.6 PXF48274.1 - 0.61 10.8 4.6 1.2 9.8 4.6 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain TraB PF01963.17 PXF48275.1 - 7.4e-06 26.0 0.3 2.3e-05 24.5 0.3 1.9 1 1 0 1 1 1 1 TraB family Rubi_NSP_C PF12601.8 PXF48275.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Rubivirus non-structural protein DUF676 PF05057.14 PXF48276.1 - 3.8e-14 52.7 0.0 6.3e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) zf-Tim10_DDP PF02953.15 PXF48277.1 - 6.6e-18 64.1 7.3 6.6e-18 64.1 7.3 2.1 2 1 1 3 3 3 1 Tim10/DDP family zinc finger ArAE_2_N PF10337.9 PXF48277.1 - 0.72 8.8 4.7 0.92 8.5 4.7 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Amidohydro_1 PF01979.20 PXF48278.1 - 7.5e-70 235.9 0.7 9.9e-70 235.5 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PXF48278.1 - 6.7e-18 65.4 0.3 5.3e-15 55.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 PXF48278.1 - 0.00034 20.1 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase 3-HAO PF06052.12 PXF48279.1 - 3e-62 208.7 0.0 3.4e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 PXF48279.1 - 8.7e-09 35.0 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 PXF48279.1 - 0.00049 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 PXF48279.1 - 0.00084 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 PXF48279.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 PXF48279.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family PP2C PF00481.21 PXF48280.1 - 4.1e-32 111.8 0.1 5.4e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF48280.1 - 3.2e-08 33.5 1.3 1.4e-07 31.4 1.3 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C DnaJ PF00226.31 PXF48281.1 - 6.1e-27 93.5 3.1 8.1e-27 93.1 3.1 1.2 1 0 0 1 1 1 1 DnaJ domain VWA PF00092.28 PXF48282.1 - 3.4e-26 92.5 0.0 4.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF48282.1 - 9.5e-18 64.8 0.2 1.6e-17 64.1 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF48282.1 - 3.3e-08 33.6 0.1 4.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PXF48282.1 - 2.4e-05 23.8 0.2 4.4e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein F-box PF00646.33 PXF48282.1 - 0.00024 20.9 0.4 0.00047 20.0 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PXF48282.1 - 0.00033 20.5 1.4 0.00069 19.4 1.4 1.6 1 0 0 1 1 1 1 F-box-like DUF2201 PF09967.9 PXF48282.1 - 0.099 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) tRNA-synt_1b PF00579.25 PXF48288.1 - 1.1e-59 202.2 0.0 1.4e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3523 PF12037.8 PXF48289.1 - 7.4e-75 251.7 27.8 1.4e-74 250.8 27.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 PXF48289.1 - 1.5e-22 80.5 0.0 3.8e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GREB1 PF15782.5 PXF48289.1 - 0.00032 18.0 4.2 0.00043 17.6 4.2 1.1 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer RuvB_N PF05496.12 PXF48289.1 - 0.00047 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PXF48289.1 - 0.0012 18.3 0.1 0.0041 16.5 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 PXF48289.1 - 0.0023 18.1 0.0 0.0057 16.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 PXF48289.1 - 0.0024 17.9 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PXF48289.1 - 0.0026 18.1 10.0 0.004 17.6 0.0 3.1 2 2 1 3 3 2 2 AAA ATPase domain Rad17 PF03215.15 PXF48289.1 - 0.0037 17.2 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 PXF48289.1 - 0.0092 16.0 0.2 0.11 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PXF48289.1 - 0.0095 15.2 0.0 0.029 13.6 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PXF48289.1 - 0.011 16.3 5.5 0.012 16.2 0.0 3.5 4 1 0 4 4 4 0 AAA domain AAA_22 PF13401.6 PXF48289.1 - 0.011 16.0 4.7 0.61 10.4 0.1 3.4 3 2 0 4 4 3 0 AAA domain AAA_33 PF13671.6 PXF48289.1 - 0.011 15.9 0.0 0.011 15.9 0.0 2.7 3 1 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 PXF48289.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 PXF48289.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PXF48289.1 - 0.031 14.0 0.0 0.1 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF48289.1 - 0.06 13.3 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sulfatase PF00884.23 PXF48289.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Sulfatase RNA_helicase PF00910.22 PXF48289.1 - 0.18 12.2 0.0 0.59 10.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 PXF48289.1 - 0.68 9.7 0.0 0.68 9.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 PXF48289.1 - 1.3 8.6 5.6 0.34 10.5 0.9 2.3 2 1 0 2 2 1 0 AAA domain Borrelia_P83 PF05262.11 PXF48289.1 - 2 6.8 19.7 3.2 6.1 19.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Sas10 PF09368.10 PXF48290.1 - 9.8e-19 67.6 7.6 9.8e-19 67.6 7.6 3.5 3 1 1 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 PXF48290.1 - 0.00044 20.8 2.2 0.0016 19.0 0.0 3.1 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF218 PF02698.17 PXF48291.1 - 4e-18 65.7 0.0 5.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Sec1 PF00995.23 PXF48292.1 - 1.1e-93 315.4 0.0 1.3e-93 315.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MMR_HSR1 PF01926.23 PXF48293.1 - 7.1e-08 32.5 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 PXF48293.1 - 1.8e-06 27.6 0.0 0.00043 19.9 0.0 2.7 2 1 0 2 2 2 1 Ras family Roc PF08477.13 PXF48293.1 - 7.4e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF48293.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 PXF48293.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 PXF48293.1 - 0.02 15.4 0.0 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 PXF48293.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 PXF48293.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 PXF48293.1 - 0.22 11.6 0.0 0.74 9.8 0.0 1.8 1 1 1 2 2 2 0 Dynamin family Arm PF00514.23 PXF48294.1 - 2.7e-10 39.9 2.7 0.28 11.3 0.0 6.6 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 PXF48294.1 - 2e-08 34.2 1.0 0.00012 22.0 0.1 4.4 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RYDR_ITPR PF01365.21 PXF48294.1 - 0.0049 16.3 0.4 0.065 12.7 0.0 2.8 2 1 1 3 3 3 1 RIH domain Peptidase_C12 PF01088.21 PXF48295.1 - 5.2e-62 209.3 0.0 6.1e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Carbam_trans_N PF02543.15 PXF48296.1 - 1.1e-11 45.1 0.3 1.6e-10 41.2 0.3 2.0 1 1 0 1 1 1 1 Carbamoyltransferase N-terminus Lipase_3 PF01764.25 PXF48297.1 - 5.7e-27 94.3 0.0 1.1e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PXF48297.1 - 0.005 16.1 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF48297.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1418 PF07214.12 PXF48297.1 - 2 8.3 5.3 12 5.8 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) AMP-binding PF00501.28 PXF48298.1 - 1.1e-45 156.0 0.0 1.3e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 PXF48298.1 - 0.0016 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 PXF48298.1 - 0.0037 18.2 0.0 0.0083 17.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-DNL PF05180.12 PXF48299.1 - 9.8e-22 76.7 0.9 1.4e-21 76.1 0.9 1.2 1 0 0 1 1 1 1 DNL zinc finger Zn_Tnp_IS1 PF03811.13 PXF48299.1 - 0.17 11.6 1.4 3.9 7.3 0.2 2.8 3 0 0 3 3 3 0 InsA N-terminal domain T_cell_tran_alt PF15128.6 PXF48300.1 - 0.00099 18.9 1.5 0.0012 18.7 0.3 1.7 1 1 1 2 2 2 1 T-cell leukemia translocation-altered AbrB PF05145.12 PXF48300.1 - 0.003 16.6 0.0 0.0032 16.5 0.0 1.0 1 0 0 1 1 1 1 Transition state regulatory protein AbrB Transket_pyr PF02779.24 PXF48301.1 - 3.7e-65 218.9 0.0 6.2e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 PXF48301.1 - 4.6e-63 213.0 0.0 8.3e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 PXF48301.1 - 3.8e-54 182.5 0.0 6.4e-54 181.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 PXF48301.1 - 1.8e-15 56.3 0.1 3.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus SHOCT PF09851.9 PXF48301.1 - 0.064 13.0 1.5 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 Short C-terminal domain LMWPc PF01451.21 PXF48303.1 - 4.4e-10 40.1 0.1 5.6e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1992 PF09350.10 PXF48304.1 - 7.3e-13 48.5 0.3 3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) PIEZO PF15917.5 PXF48304.1 - 0.14 11.7 1.3 0.15 11.6 0.4 1.5 2 0 0 2 2 2 0 Piezo Transcrip_reg PF01709.20 PXF48305.1 - 4.8e-12 45.8 0.5 5.3e-12 45.7 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator MFS_1 PF07690.16 PXF48306.1 - 1.8e-22 79.8 71.8 3.1e-18 65.8 40.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioredoxin_7 PF13899.6 PXF48309.1 - 1.9e-16 60.0 0.0 4.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 PXF48309.1 - 2.9e-13 49.8 0.0 5.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PXF48309.1 - 1.5e-10 40.8 0.5 2.8e-10 39.8 0.5 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.15 PXF48309.1 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 TAP_C PF03943.13 PXF48309.1 - 0.0044 16.6 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain Thioredoxin_2 PF13098.6 PXF48309.1 - 0.12 12.8 0.2 0.41 11.1 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin-like domain YABBY PF04690.13 PXF48309.1 - 0.52 10.9 2.2 0.85 10.2 2.2 1.3 1 0 0 1 1 1 0 YABBY protein Rxt3 PF08642.10 PXF48310.1 - 3.2e-12 47.3 0.3 2.5e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 PXF48310.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 LCCL domain bZIP_2 PF07716.15 PXF48311.1 - 0.15 12.2 6.2 0.31 11.2 6.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PWWP PF00855.17 PXF48312.1 - 9.7e-16 58.0 0.8 5.3e-15 55.6 0.0 2.6 2 0 0 2 2 2 1 PWWP domain NYN PF01936.18 PXF48313.1 - 4.2e-14 53.3 0.0 1.1e-13 51.9 0.0 1.7 1 0 0 1 1 1 1 NYN domain AF-4 PF05110.13 PXF48313.1 - 3 5.8 46.3 5.6 4.9 46.3 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ORMDL PF04061.14 PXF48314.1 - 2.6e-32 111.5 4.0 2.9e-32 111.3 4.0 1.0 1 0 0 1 1 1 1 ORMDL family CEBP_ZZ PF16366.5 PXF48314.1 - 0.08 13.2 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF3784 PF12650.7 PXF48314.1 - 4.7 7.5 6.3 7.5 6.8 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) ABC_tran PF00005.27 PXF48315.1 - 8.5e-35 120.2 0.1 1.7e-34 119.2 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 PXF48315.1 - 5.1e-27 95.2 1.6 7.8e-27 94.6 1.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PXF48315.1 - 5.7e-05 22.6 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 PXF48315.1 - 0.0012 18.2 0.2 0.0059 15.9 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 PXF48315.1 - 0.0024 18.3 0.1 0.007 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 PXF48315.1 - 0.0044 15.9 0.3 0.0073 15.2 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 PXF48315.1 - 0.012 15.6 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PXF48315.1 - 0.014 15.0 0.7 0.13 11.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PXF48315.1 - 0.019 14.7 0.2 1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 PXF48315.1 - 0.019 14.6 0.4 0.89 9.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 PXF48315.1 - 0.029 14.1 0.4 0.064 13.0 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PXF48315.1 - 0.029 14.7 1.6 0.72 10.1 1.6 2.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PXF48315.1 - 0.037 13.4 0.1 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 PXF48315.1 - 0.049 13.4 0.6 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 PXF48315.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 PXF48315.1 - 0.068 13.4 0.1 0.31 11.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 PXF48315.1 - 0.081 12.8 0.9 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 PXF48315.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 PXF48315.1 - 0.14 11.9 0.2 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase PH_9 PF15410.6 PXF48316.1 - 0.11 12.9 1.1 0.34 11.3 0.1 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain L51_S25_CI-B8 PF05047.16 PXF48317.1 - 1.3e-11 44.2 0.0 1.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GRDP-like PF07173.12 PXF48318.1 - 0.12 13.0 0.2 0.47 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycine-rich domain-containing protein-like PMI_typeI PF01238.21 PXF48319.1 - 3.3e-33 115.4 0.0 4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I CdiI_3 PF18616.1 PXF48319.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 CDI immunity proteins LSM PF01423.22 PXF48320.1 - 4.5e-18 64.7 0.0 5.6e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PXF48320.1 - 0.0042 16.7 0.1 0.0078 15.8 0.1 1.5 1 0 0 1 1 1 1 Hfq protein SM-ATX PF14438.6 PXF48320.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 PXF48320.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Fasciclin PF02469.22 PXF48321.1 - 1.5e-25 89.9 0.0 2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain STN PF07660.14 PXF48321.1 - 0.017 14.9 0.1 1.5 8.7 0.0 2.4 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain PseudoU_synth_1 PF01416.20 PXF48322.1 - 5.7e-13 49.3 0.1 2.7e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase NeA_P2 PF12312.8 PXF48323.1 - 0.93 8.9 5.9 3.3 7.1 2.0 2.2 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Mon2_C PF16206.5 PXF48324.1 - 2.2e-37 128.7 0.2 7.8e-25 87.2 0.0 4.5 4 1 1 5 5 5 3 C-terminal region of Mon2 protein DCB PF16213.5 PXF48324.1 - 3.6e-20 72.4 5.8 1.2e-19 70.6 2.4 2.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 PXF48324.1 - 1e-13 51.5 0.1 1e-13 51.5 0.1 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PXF48324.1 - 0.0026 17.6 0.1 0.025 14.4 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Put_Phosphatase PF06888.12 PXF48325.1 - 1.4e-49 168.6 0.0 1.6e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 PXF48325.1 - 0.013 15.8 0.7 2.6 8.3 0.1 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF48325.1 - 0.019 15.4 1.2 0.3 11.5 1.2 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase A_deaminase PF00962.22 PXF48326.1 - 9e-107 357.2 0.0 1.3e-106 356.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Spindle_Spc25 PF08234.12 PXF48328.1 - 3.8e-10 39.8 0.7 9.9e-10 38.5 0.7 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 PXF48328.1 - 0.0021 17.0 10.3 0.0021 17.0 10.3 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein ADIP PF11559.8 PXF48328.1 - 0.11 12.5 11.8 0.12 12.5 10.7 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-K PF11802.8 PXF48328.1 - 0.25 10.9 10.3 0.16 11.5 7.7 1.7 1 1 1 2 2 2 0 Centromere-associated protein K V_ATPase_I PF01496.19 PXF48328.1 - 0.34 8.8 6.5 0.41 8.5 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliD_N PF02465.18 PXF48328.1 - 0.5 11.1 3.5 1.3 9.8 3.1 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 PXF48328.1 - 0.71 9.9 8.8 0.28 11.2 2.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 PXF48328.1 - 0.73 7.7 6.4 0.97 7.3 6.4 1.2 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 PXF48328.1 - 1.5 8.9 14.0 0.62 10.1 11.6 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HisKA_3 PF07730.13 PXF48328.1 - 1.6 9.3 7.9 1.9 9.0 2.0 3.2 2 1 1 3 3 3 0 Histidine kinase DUF2203 PF09969.9 PXF48328.1 - 1.8 9.3 9.0 1.8 9.3 2.9 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) PhoU PF01895.19 PXF48328.1 - 2.9 8.4 9.1 4.6 7.8 4.2 3.0 2 1 1 3 3 3 0 PhoU domain Exonuc_VII_L PF02601.15 PXF48328.1 - 3.3 7.2 8.6 4.6 6.7 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 PXF48328.1 - 4.3 7.6 15.7 1.1 9.6 9.4 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.22 PXF48328.1 - 5.6 7.3 14.3 4.9 7.4 7.1 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain C2 PF00168.30 PXF48329.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Homeodomain PF00046.29 PXF48330.1 - 1.3e-10 41.0 0.0 3.6e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain TusA PF01206.17 PXF48330.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA FTR1 PF03239.14 PXF48331.1 - 1.5e-47 162.2 8.4 1.5e-47 162.2 8.4 2.1 3 0 0 3 3 3 1 Iron permease FTR1 family Zn_peptidase_2 PF04298.12 PXF48331.1 - 0.58 9.5 5.5 1.1 8.6 3.5 2.5 1 1 1 2 2 2 0 Putative neutral zinc metallopeptidase Esterase_phd PF10503.9 PXF48332.1 - 9.2e-05 22.0 0.0 0.00032 20.3 0.0 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase PAPA-1 PF04795.12 PXF48333.1 - 7.8e-12 45.8 6.9 7.8e-12 45.8 6.9 4.1 3 2 2 5 5 5 1 PAPA-1-like conserved region Nucleotid_trans PF03407.16 PXF48334.1 - 7.7e-31 107.7 0.0 1.1e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CTP_transf_3 PF02348.19 PXF48334.1 - 0.21 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DASH_Duo1 PF08651.10 PXF48335.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF1325 PF07039.11 PXF48336.1 - 2e-22 79.7 0.3 3.1e-22 79.1 0.3 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 PXF48336.1 - 0.00015 22.2 0.3 0.18 12.3 0.0 2.3 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.6 PXF48336.1 - 0.00052 20.0 0.1 0.44 10.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) DUF4819 PF16090.5 PXF48336.1 - 0.013 15.6 0.1 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4819) DUF910 PF06014.11 PXF48338.1 - 0.32 11.0 3.7 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) FUSC PF04632.12 PXF48338.1 - 0.79 8.2 4.2 1.3 7.4 4.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family MoaE PF02391.17 PXF48339.1 - 4e-41 139.8 0.1 4.7e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 MoaE protein T2SSE_N PF05157.15 PXF48339.1 - 0.029 14.6 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain Hyd_WA PF06462.12 PXF48339.1 - 1.5 8.9 3.5 40 4.3 0.0 3.4 4 0 0 4 4 4 0 Propeller ThiS PF02597.20 PXF48340.1 - 2.3e-12 47.4 0.0 3.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family EF-hand_4 PF12763.7 PXF48341.1 - 1.4e-20 73.2 0.0 4.2e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 PXF48341.1 - 1.2e-07 32.1 0.0 0.002 18.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PXF48341.1 - 1.8e-07 30.2 0.2 0.00011 21.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF48341.1 - 3.3e-06 26.6 2.2 0.01 15.7 0.0 3.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 PXF48341.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 EF hand UPF0242 PF06785.11 PXF48341.1 - 0.025 14.7 0.3 0.043 13.9 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PIEZO PF15917.5 PXF48341.1 - 0.15 11.5 0.8 0.33 10.4 0.8 1.5 1 0 0 1 1 1 0 Piezo EF-hand_8 PF13833.6 PXF48341.1 - 0.16 11.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EamA PF00892.20 PXF48342.1 - 2.5e-19 69.8 26.4 7.3e-11 42.4 9.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PXF48342.1 - 0.12 11.7 13.7 0.51 9.6 3.8 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family HKR_ArcB_TM PF18415.1 PXF48342.1 - 0.52 11.1 0.1 0.52 11.1 0.1 3.6 4 0 0 4 4 4 0 Histidine kinase receptor ArcB trans-membrane domain PseudoU_synth_2 PF00849.22 PXF48343.1 - 8.4e-23 81.2 0.0 1.5e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase GFO_IDH_MocA PF01408.22 PXF48345.1 - 3.7e-21 76.2 0.0 7.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF48345.1 - 1.1e-12 47.9 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 PXF48345.1 - 0.0054 16.1 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PXF48345.1 - 0.015 15.6 0.1 0.14 12.5 0.1 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 PXF48345.1 - 0.067 13.3 0.1 0.23 11.6 0.0 2.0 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 PXF48345.1 - 0.068 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PXF48345.1 - 0.088 13.4 0.0 0.47 11.1 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 PXF48346.1 - 8.6e-49 166.5 0.2 1.1e-48 166.2 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CPP1-like PF11833.8 PXF48347.1 - 8.8e-10 38.6 0.0 3.2e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 PXF48347.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain WD40 PF00400.32 PXF48348.1 - 9.1e-27 92.8 13.6 4.4e-07 30.5 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.6 PXF48348.1 - 0.00074 19.2 1.2 0.0036 16.9 1.2 2.1 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 PXF48348.1 - 0.00093 19.5 0.1 0.68 10.3 0.0 3.8 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PXF48348.1 - 0.0091 14.7 0.1 1.8 7.1 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 TFIIF_alpha PF05793.12 PXF48348.1 - 0.15 10.6 11.6 0.21 10.2 11.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 PXF48348.1 - 3 7.1 12.3 4 6.7 12.3 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 PXF48348.1 - 5.6 5.4 6.6 7.9 4.9 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SMC_N PF02463.19 PXF48349.1 - 2.3e-09 37.0 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 PXF48349.1 - 0.014 15.6 0.5 0.093 13.0 0.1 2.2 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 PXF48350.1 - 4.4e-12 46.4 0.2 1.6e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 PXF48350.1 - 6.1e-10 38.9 0.1 6.1e-10 38.9 0.1 2.2 3 0 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PXF48350.1 - 2.3e-06 28.2 28.0 2.3e-06 28.2 28.0 4.4 2 2 0 2 2 1 1 AAA domain DUF1664 PF07889.12 PXF48350.1 - 0.00015 21.8 26.8 0.0061 16.6 2.5 5.1 3 1 0 4 4 4 3 Protein of unknown function (DUF1664) AAA_29 PF13555.6 PXF48350.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 PXF48350.1 - 0.0022 18.5 66.4 0.0041 17.6 6.7 4.9 3 1 1 4 4 4 2 Apg6 coiled-coil region Laminin_II PF06009.12 PXF48350.1 - 0.2 11.6 34.0 1.1 9.3 5.7 5.3 3 1 2 5 5 5 0 Laminin Domain II AAA_21 PF13304.6 PXF48350.1 - 0.26 11.1 0.1 0.26 11.1 0.1 3.0 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF948 PF06103.11 PXF48350.1 - 0.32 11.3 17.0 0.69 10.2 0.6 4.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 PXF48350.1 - 0.4 10.7 54.6 0.092 12.8 12.8 4.6 3 1 1 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PXF48350.1 - 0.54 10.7 16.0 0.41 11.1 0.5 5.4 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) T7SS_ESX_EspC PF10824.8 PXF48350.1 - 2.1 8.9 5.2 6.2 7.4 0.0 3.7 3 1 1 4 4 3 0 Excreted virulence factor EspC, type VII ESX diderm THP2 PF09432.10 PXF48350.1 - 2.3 8.3 23.2 7.5 6.6 1.3 4.3 2 2 0 3 3 3 0 Tho complex subunit THP2 NPV_P10 PF05531.12 PXF48350.1 - 4.7 7.8 16.6 4.3 7.9 0.2 5.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_16 PF13191.6 PXF48350.1 - 5.7 7.3 0.0 5.7 7.3 0.0 3.8 4 1 0 4 4 4 0 AAA ATPase domain DUF4982 PF16355.5 PXF48351.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) HlyIII PF03006.20 PXF48352.1 - 5.8e-29 101.4 14.0 5.8e-29 101.4 14.0 2.0 2 0 0 2 2 2 1 Haemolysin-III related LRR_8 PF13855.6 PXF48352.1 - 0.0049 16.6 1.8 0.019 14.7 0.2 2.8 2 1 0 2 2 2 1 Leucine rich repeat DUF4231 PF14015.6 PXF48352.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF4231) LRR_4 PF12799.7 PXF48352.1 - 2.5 8.6 10.7 4.9 7.7 6.0 3.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) IGPD PF00475.18 PXF48356.1 - 2.1e-60 203.2 0.4 3.3e-60 202.6 0.4 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Esterase_phd PF10503.9 PXF48357.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Nnf1 PF03980.14 PXF48358.1 - 0.00085 19.7 3.4 0.00085 19.7 3.4 1.6 2 0 0 2 2 2 1 Nnf1 COMPASS-Shg1 PF05205.12 PXF48358.1 - 0.016 15.9 2.4 0.11 13.2 1.8 2.1 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Spc29 PF17082.5 PXF48358.1 - 0.017 15.0 4.0 0.022 14.6 2.8 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 Arg_decarbox_C PF17944.1 PXF48358.1 - 0.021 15.4 0.4 1.1 9.9 0.0 2.5 2 1 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Lzipper-MIP1 PF14389.6 PXF48358.1 - 0.026 14.8 4.9 2.3 8.6 1.9 2.7 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 STAT_alpha PF01017.20 PXF48358.1 - 0.04 13.8 1.3 0.04 13.8 1.3 1.7 2 0 0 2 2 2 0 STAT protein, all-alpha domain Herpes_UL92 PF03048.14 PXF48358.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 UL92 family FAM76 PF16046.5 PXF48358.1 - 0.11 11.8 4.4 0.13 11.6 4.4 1.1 1 0 0 1 1 1 0 FAM76 protein Fib_alpha PF08702.10 PXF48358.1 - 0.19 11.9 5.0 0.46 10.7 5.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlgN PF05130.12 PXF48358.1 - 0.63 10.5 6.8 0.27 11.7 2.4 2.1 2 0 0 2 2 2 0 FlgN protein DSHCT PF08148.12 PXF48359.1 - 4e-32 111.2 0.1 1.1e-31 109.7 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PXF48359.1 - 1e-14 54.7 0.0 2.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PXF48359.1 - 6.8e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PXF48359.1 - 9.4e-06 25.9 0.0 2.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NT5C PF06941.12 PXF48360.1 - 9.8e-20 71.2 0.1 1.2e-19 70.8 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) WD40 PF00400.32 PXF48361.1 - 1.1e-32 111.6 21.9 3.9e-05 24.3 0.1 10.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48361.1 - 4.7e-18 65.3 0.0 0.00059 20.1 0.0 6.3 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF48361.1 - 5.5e-09 35.4 1.7 0.024 13.6 0.0 4.4 3 3 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PXF48361.1 - 1.9e-07 30.7 0.2 0.0011 18.3 0.1 3.5 3 0 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 PXF48361.1 - 5.8e-06 26.3 0.0 1.1 9.1 0.0 3.4 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PXF48361.1 - 0.00011 22.0 0.2 39 4.3 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 PXF48361.1 - 0.008 15.3 0.0 5 6.0 0.0 3.0 3 0 0 3 3 3 1 Coatomer WD associated region Nbas_N PF15492.6 PXF48361.1 - 0.043 13.2 0.0 4.3 6.6 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 PXF48361.1 - 0.049 12.3 0.1 2.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WD40_3 PF15911.5 PXF48361.1 - 0.12 12.4 0.1 8.7 6.4 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.16 PXF48362.1 - 3.9e-05 22.7 44.9 0.00074 18.5 19.7 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily PH PF00169.29 PXF48363.1 - 9.9e-06 26.0 0.0 2.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 PXF48363.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Syntaxin PF00804.25 PXF48365.1 - 9.7e-21 74.4 4.2 9.7e-21 74.4 4.2 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 PXF48365.1 - 1.2e-14 54.0 6.6 2.3e-14 53.1 2.9 2.4 2 0 0 2 2 2 1 SNARE domain SKA2 PF16740.5 PXF48365.1 - 0.0068 16.2 7.2 0.21 11.4 0.1 2.6 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 EspB_PE PF18625.1 PXF48365.1 - 0.014 15.8 3.1 0.036 14.5 0.3 2.7 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain SKA1 PF07160.12 PXF48365.1 - 0.022 14.6 7.3 0.11 12.4 3.8 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Arfaptin PF06456.13 PXF48365.1 - 0.022 14.3 5.4 0.046 13.3 3.1 2.0 1 1 1 2 2 2 0 Arfaptin-like domain Herpes_US9 PF06072.11 PXF48365.1 - 0.069 13.0 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Spectrin PF00435.21 PXF48365.1 - 0.1 13.1 5.2 0.79 10.2 0.0 2.9 1 1 2 3 3 3 0 Spectrin repeat LMBR1 PF04791.16 PXF48365.1 - 0.11 11.4 1.6 0.14 11.1 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 PXF48365.1 - 0.16 12.0 0.2 0.16 12.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4834 PF16118.5 PXF48365.1 - 0.29 12.1 2.7 1.4 9.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Rab5-bind PF09311.11 PXF48365.1 - 0.3 10.4 10.9 0.14 11.5 6.1 2.0 1 1 1 2 2 2 0 Rabaptin-like protein INCA1 PF15142.6 PXF48365.1 - 0.31 11.1 1.3 7.8 6.5 0.2 2.2 2 0 0 2 2 2 0 INCA1 Helo_like_N PF17111.5 PXF48365.1 - 0.37 10.1 6.6 0.38 10.1 1.9 2.3 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins NPV_P10 PF05531.12 PXF48365.1 - 0.53 10.8 8.4 15 6.1 0.1 3.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 PXF48365.1 - 0.57 10.1 6.2 16 5.4 5.2 2.7 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SOAR PF16533.5 PXF48365.1 - 0.78 9.7 4.9 19 5.3 0.9 2.9 2 1 0 2 2 2 0 STIM1 Orai1-activating region FUSC PF04632.12 PXF48365.1 - 2.2 6.7 7.4 6 5.3 2.6 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family P4Ha_N PF08336.11 PXF48365.1 - 6 6.9 8.2 1.8 8.6 1.7 2.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TMF_TATA_bd PF12325.8 PXF48365.1 - 6.3 7.1 9.3 2.1 8.6 4.5 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 PXF48365.1 - 7.9 7.2 8.3 2.2e+03 -0.7 8.3 3.1 1 1 0 1 1 1 0 Initiation control protein YabA Ndc1_Nup PF09531.10 PXF48366.1 - 1.1e-08 34.3 0.1 1.1e-08 34.3 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin protein Ndc1-Nup EAF PF09816.9 PXF48367.1 - 4.6e-10 39.8 0.0 7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Imm5 PF14423.6 PXF48370.1 - 0.084 13.1 0.1 0.085 13.1 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 DDE_1 PF03184.19 PXF48371.1 - 9.9e-40 136.0 0.0 1.6e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF48371.1 - 0.016 15.2 0.3 0.072 13.1 0.2 2.2 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain Carboxyl_trans PF01039.22 PXF48372.1 - 9.4e-154 512.7 0.0 1.3e-153 512.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 PXF48372.1 - 1.4e-129 433.5 0.0 4.1e-90 303.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 PXF48372.1 - 1.4e-49 168.4 0.0 2.6e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PXF48372.1 - 4.2e-28 98.1 0.0 1.2e-27 96.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PXF48372.1 - 7.6e-22 77.5 0.0 1.9e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PXF48372.1 - 9.5e-12 44.6 0.1 2.4e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 PXF48372.1 - 3.3e-06 26.8 0.1 7e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 PXF48372.1 - 6.6e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PXF48372.1 - 0.0065 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PXF48372.1 - 0.033 14.0 0.0 3 7.7 0.0 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like Fructosamin_kin PF03881.14 PXF48373.1 - 4.4e-74 249.3 0.0 5.4e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 PXF48373.1 - 2.6e-07 30.8 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Goodbye PF17109.5 PXF48374.1 - 0.1 13.1 0.0 0.66 10.4 0.0 2.5 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain SNF2_N PF00176.23 PXF48375.1 - 2.3e-52 177.8 0.0 4.4e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF48375.1 - 3.4e-15 56.3 0.0 1.1e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48375.1 - 3.7e-09 36.8 0.0 1.8e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2439 PF10382.9 PXF48375.1 - 1.4e-07 31.7 2.1 2e-07 31.3 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) DEAD PF00270.29 PXF48375.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PXF48375.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 PXF48375.1 - 0.13 11.1 0.0 0.76 8.6 0.0 2.2 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 NUMOD3 PF07460.11 PXF48376.1 - 0.92 9.8 6.3 1.5 9.1 0.8 2.6 2 1 1 3 3 3 0 NUMOD3 motif (2 copies) DUF866 PF05907.13 PXF48377.1 - 2.4e-32 112.0 0.0 2.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 PXF48377.1 - 0.26 10.8 1.7 18 4.9 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding PolyA_pol PF01743.20 PXF48378.1 - 4.1e-22 79.0 0.1 8.5e-22 77.9 0.1 1.5 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 PXF48378.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Adeno_VII PF03228.14 PXF48379.1 - 0.047 14.3 0.1 0.12 13.0 0.1 1.7 1 0 0 1 1 1 0 Adenoviral core protein VII Sec61_beta PF03911.16 PXF48380.1 - 1.2e-07 31.6 2.0 2.2e-07 30.8 2.0 1.4 1 0 0 1 1 1 1 Sec61beta family Tlr3_TMD PF17968.1 PXF48380.1 - 0.16 12.2 0.9 0.32 11.2 0.9 1.6 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Ala_racemase_N PF01168.20 PXF48381.1 - 1.4e-25 90.3 0.0 1.6e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF1707 PF08044.11 PXF48381.1 - 0.43 10.7 1.5 27 4.9 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1707) MAD PF05557.13 PXF48382.1 - 1.4e-26 93.1 72.0 2.2e-25 89.2 72.6 2.1 1 1 0 1 1 1 1 Mitotic checkpoint protein PKcGMP_CC PF16808.5 PXF48382.1 - 2.3 8.1 16.3 3.7 7.5 0.3 5.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IFP_35_N PF07334.13 PXF48382.1 - 5.4 7.2 17.1 6.7 6.9 0.5 5.1 4 0 0 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Proteasome PF00227.26 PXF48383.1 - 2e-30 105.7 0.0 2.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldo_ket_red PF00248.21 PXF48384.1 - 3.6e-65 220.1 0.0 4.2e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Med27 PF11571.8 PXF48385.1 - 1.5e-09 38.0 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 EF-G-binding_N PF07299.11 PXF48385.1 - 0.15 12.6 0.1 15 6.2 0.2 2.3 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Phage_lysis PF03245.13 PXF48386.1 - 0.11 12.7 3.5 0.11 12.7 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein CRT-like PF08627.10 PXF48387.1 - 7.8e-11 41.5 10.1 1.5e-10 40.6 2.4 2.2 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 PXF48387.1 - 2.3e-07 30.6 19.4 5.8e-07 29.3 19.4 1.7 1 1 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 PXF48387.1 - 1.1e-05 24.8 8.7 0.00015 21.1 8.9 2.4 1 1 1 2 2 2 1 UAA transporter family PUNUT PF16913.5 PXF48387.1 - 2.8e-05 23.5 7.3 0.00019 20.7 7.5 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 PXF48387.1 - 4.3e-05 23.0 3.7 7.6e-05 22.2 3.7 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 PXF48387.1 - 0.00076 18.7 1.8 0.00076 18.7 1.8 2.6 2 1 1 3 3 3 1 Nucleotide-sugar transporter EamA PF00892.20 PXF48387.1 - 0.0021 18.2 9.3 0.0021 18.2 9.3 4.0 2 2 1 3 3 3 1 EamA-like transporter family DUF2556 PF10831.8 PXF48387.1 - 0.033 14.1 0.6 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2556) PUA PF01472.20 PXF48387.1 - 0.046 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 PUA domain Pentapeptide PF00805.22 PXF48388.1 - 1e-17 63.4 20.5 1e-07 31.5 1.1 3.3 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PXF48388.1 - 3.4e-11 43.1 4.6 6.5e-06 26.2 1.5 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PXF48388.1 - 9.1e-11 41.8 10.9 7.7e-05 22.8 2.2 3.2 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pkinase PF00069.25 PXF48389.1 - 4.8e-62 209.7 0.0 6.2e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48389.1 - 4.3e-31 108.1 0.0 5.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF48389.1 - 8e-09 35.2 0.1 4e-05 23.1 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PXF48389.1 - 0.00013 21.0 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF48389.1 - 0.054 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PXF48389.1 - 0.066 12.8 0.0 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EB1 PF03271.17 PXF48390.1 - 3.4e-11 43.2 1.1 3e-10 40.2 0.2 2.4 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 PXF48390.1 - 2.4e-08 34.1 0.4 4.7e-08 33.2 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PXF48390.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain HALZ PF02183.18 PXF48390.1 - 0.031 14.5 0.4 0.031 14.5 0.4 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 PXF48390.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.9 4 0 0 4 4 4 0 Septum formation initiator Aminotran_1_2 PF00155.21 PXF48391.1 - 2.1e-79 267.4 0.0 2.3e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.28 PXF48392.1 - 2e-49 168.3 0.0 2e-49 168.3 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF48392.1 - 5.2e-08 33.8 0.3 8.2e-07 29.9 0.0 3.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain DUF1196 PF06709.11 PXF48392.1 - 0.051 13.7 0.4 0.17 12.0 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) Hamartin PF04388.12 PXF48392.1 - 5.8 5.4 13.8 8.2 5.0 13.8 1.3 1 0 0 1 1 1 0 Hamartin protein DDE_1 PF03184.19 PXF48393.1 - 5.2e-33 114.2 0.1 8.9e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 PXF48393.1 - 2.8e-07 30.4 0.1 9.1e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 PXF48393.1 - 1.1e-06 28.1 0.8 3e-06 26.8 0.8 1.8 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.6 PXF48393.1 - 0.067 12.9 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease CBM_20 PF00686.19 PXF48396.1 - 1.9e-09 37.3 0.0 3.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Mem_trans PF03547.18 PXF48397.1 - 1.8e-19 69.4 29.4 2.3e-13 49.3 9.4 2.1 2 0 0 2 2 2 2 Membrane transport protein FAD_binding_3 PF01494.19 PXF48399.1 - 8.4e-16 58.1 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Aminotran_1_2 PF00155.21 PXF48400.1 - 4.7e-85 285.9 0.0 5.4e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glycos_transf_1 PF00534.20 PXF48401.1 - 1.3e-19 70.3 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PXF48401.1 - 2.4e-16 60.4 0.0 4.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 PXF48401.1 - 4.6e-09 36.3 0.4 1.4e-08 34.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_1_2 PF13524.6 PXF48401.1 - 4e-08 33.5 0.0 1.5e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 PXF48401.1 - 0.002 18.1 0.0 0.0071 16.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pox_P35 PF03213.14 PXF48401.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein TetR_C_23 PF17931.1 PXF48401.1 - 0.071 13.2 0.6 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PUF PF00806.19 PXF48401.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Ribosomal_L10 PF00466.20 PXF48403.1 - 5e-19 68.3 0.0 8.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 PXF48403.1 - 1.6e-18 66.5 0.0 2.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L37ae PF01780.19 PXF48404.1 - 6.4e-39 131.9 8.9 7.2e-39 131.8 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 PXF48404.1 - 0.0037 17.2 1.2 0.0058 16.6 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 PXF48404.1 - 0.018 14.4 2.1 0.043 13.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 PXF48404.1 - 0.058 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-HIT PF04438.16 PXF48404.1 - 0.087 12.7 2.5 5.9 6.9 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger Elf1 PF05129.13 PXF48404.1 - 0.12 12.5 1.5 0.16 12.0 1.5 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 PXF48404.1 - 0.2 12.1 1.6 0.22 12.0 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger double domain BshC PF10079.9 PXF48405.1 - 0.028 13.2 1.2 0.031 13.0 1.2 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF3138 PF11336.8 PXF48405.1 - 0.049 12.2 4.0 1.3 7.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) YabA PF06156.13 PXF48405.1 - 0.39 11.4 4.9 0.44 11.2 4.0 1.5 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 PXF48405.1 - 2 8.2 5.5 1.5 8.7 1.8 2.0 2 0 0 2 2 2 0 Septum formation initiator HA2 PF04408.23 PXF48406.1 - 7.3e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PXF48406.1 - 6.9e-11 42.5 0.0 1.4e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PXF48406.1 - 1.9e-08 34.3 0.1 3.6e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PXF48406.1 - 2.1e-06 28.1 0.2 5.2e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF48406.1 - 0.0037 16.4 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 PXF48406.1 - 0.0043 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 PXF48406.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PXF48406.1 - 0.027 14.8 0.1 0.13 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PXF48406.1 - 0.033 13.6 0.0 0.095 12.0 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 PXF48406.1 - 0.062 13.3 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 PXF48406.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 PXF48406.1 - 0.11 12.9 0.3 1 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain UvrD-helicase PF00580.21 PXF48406.1 - 0.27 10.7 0.0 0.81 9.1 0.0 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Voltage_CLC PF00654.20 PXF48407.1 - 8.8e-37 127.2 41.5 8.7e-35 120.6 31.3 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel PG_isomerase_N PF18353.1 PXF48407.1 - 0.064 13.6 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain CD20 PF04103.15 PXF48407.1 - 0.6 10.2 8.3 0.63 10.1 0.2 3.3 3 0 0 3 3 3 0 CD20-like family EAF PF09816.9 PXF48408.1 - 2.1e-05 24.9 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DS PF01916.17 PXF48409.1 - 4.3e-126 420.0 0.0 4.9e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 PXF48409.1 - 0.027 14.1 0.1 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus DUF494 PF04361.13 PXF48409.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Pkinase PF00069.25 PXF48410.1 - 8.1e-65 218.8 0.1 9.6e-65 218.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48410.1 - 4.1e-34 118.0 0.1 5.1e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF48410.1 - 3.3e-05 22.8 0.0 4.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PXF48410.1 - 0.0083 15.5 0.0 0.066 12.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF48410.1 - 0.012 14.9 0.3 0.033 13.6 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 PXF48410.1 - 0.12 11.9 0.1 0.67 9.4 0.1 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL DUF3275 PF11679.8 PXF48411.1 - 0.22 11.5 1.9 0.34 10.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF747 PF05346.11 PXF48413.1 - 1.5e-87 294.1 16.4 2e-87 293.6 16.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RHD3 PF05879.12 PXF48414.1 - 1.6e-74 251.4 0.0 2.1e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) AAA_28 PF13521.6 PXF48414.1 - 0.0035 17.6 0.1 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PXF48414.1 - 0.0039 17.3 0.0 0.0092 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF48414.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 PXF48414.1 - 0.048 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain G-patch_2 PF12656.7 PXF48415.1 - 2.3e-10 40.4 0.9 2.3e-10 40.4 0.9 2.4 2 0 0 2 2 2 1 G-patch domain DUF3245 PF11595.8 PXF48415.1 - 0.013 16.0 0.5 0.013 16.0 0.5 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3245) Cdh1_DBD_1 PF18196.1 PXF48415.1 - 0.98 9.7 4.0 0.44 10.9 1.2 1.9 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 CENP-U PF13097.6 PXF48415.1 - 6.9 6.6 13.2 0.58 10.1 8.3 1.8 2 1 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit RNase_P_Rpp14 PF01900.19 PXF48416.1 - 7.2e-07 29.4 0.0 8.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Img2 PF05046.14 PXF48417.1 - 6.8e-19 67.9 0.0 9.5e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) zf-C3HC4_3 PF13920.6 PXF48418.1 - 4.3e-07 29.7 1.3 7.5e-07 28.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF48418.1 - 7.3e-06 25.7 2.1 9.8e-06 25.3 1.0 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PXF48418.1 - 2.9e-05 23.9 1.7 5.5e-05 23.0 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PXF48418.1 - 3.3e-05 23.7 2.6 5.9e-05 22.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PXF48418.1 - 4.7e-05 23.6 1.9 9.3e-05 22.7 1.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF48418.1 - 0.00046 20.0 2.0 0.001 18.8 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF48418.1 - 0.00073 19.8 0.4 0.0017 18.6 0.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PXF48418.1 - 0.0014 18.6 0.6 0.017 15.1 0.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger PRKG1_interact PF15898.5 PXF48418.1 - 0.0044 17.9 7.9 0.0044 17.9 7.9 7.0 3 2 4 8 8 6 1 cGMP-dependent protein kinase interacting domain zf-RING_6 PF14835.6 PXF48418.1 - 0.036 13.9 0.8 0.067 13.1 0.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 PXF48418.1 - 0.042 13.7 1.4 0.079 12.8 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn-C2H2_12 PF18112.1 PXF48418.1 - 0.046 14.2 0.8 0.093 13.2 0.1 1.9 2 0 0 2 2 1 0 Autophagy receptor zinc finger-C2H2 domain FIVAR PF07554.13 PXF48418.1 - 0.048 14.4 9.8 0.32 11.8 2.4 3.2 2 0 0 2 2 2 0 FIVAR domain zf-RING_11 PF17123.5 PXF48418.1 - 0.17 11.6 0.8 4.6 7.1 0.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 PXF48418.1 - 0.31 11.2 1.7 0.63 10.2 1.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 PXF48418.1 - 0.58 10.0 0.0 0.58 10.0 0.0 5.7 5 0 0 5 5 5 0 Rad50 zinc hook motif Fib_alpha PF08702.10 PXF48418.1 - 9.9 6.3 45.7 0.048 13.8 3.4 6.5 2 1 7 9 9 9 0 Fibrinogen alpha/beta chain family Tctex-1 PF03645.13 PXF48419.1 - 3.8e-22 78.5 2.3 4.6e-22 78.2 2.3 1.1 1 0 0 1 1 1 1 Tctex-1 family Sec23_BS PF08033.12 PXF48420.1 - 0.13 13.0 0.0 0.3 11.9 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 PXF48420.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 PXF48420.1 - 0.25 11.4 1.6 1 9.4 1.6 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger TRCF PF03461.15 PXF48421.1 - 0.069 13.5 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 TRCF domain Spore_III_AB PF09548.10 PXF48421.1 - 0.23 11.5 0.3 0.5 10.5 0.3 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) VAPB_antitox PF02697.14 PXF48421.1 - 3 8.7 6.8 7.4 7.4 6.8 1.7 1 0 0 1 1 1 0 Putative antitoxin Asp_Arg_Hydrox PF05118.15 PXF48422.1 - 5e-34 117.4 0.2 7.7e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase APH PF01636.23 PXF48423.1 - 3e-35 122.3 0.1 8.2e-35 120.9 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 PXF48423.1 - 7.7e-33 113.8 1.1 1.6e-32 112.8 1.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PXF48423.1 - 3.1e-17 62.6 0.0 6.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PXF48423.1 - 7.6e-14 52.3 0.0 1.6e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PXF48423.1 - 1.5e-11 44.7 0.8 2.7e-11 43.9 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EcKinase PF02958.20 PXF48423.1 - 2.2e-06 27.2 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 PXF48423.1 - 0.0027 17.3 0.0 0.076 12.6 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 PXF48423.1 - 0.0034 16.3 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 PXF48423.1 - 0.051 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PALP PF00291.25 PXF48424.1 - 6.9e-70 235.8 3.3 7.9e-70 235.6 3.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.24 PXF48424.1 - 0.014 15.0 0.3 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DFP PF04127.15 PXF48424.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF3450 PF11932.8 PXF48426.1 - 0.2 11.0 6.0 0.26 10.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CPSF100_C PF13299.6 PXF48426.1 - 0.53 10.4 4.9 0.19 11.9 2.3 1.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Jnk-SapK_ap_N PF09744.9 PXF48426.1 - 1.7 8.8 9.9 0.73 10.0 7.4 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 MMR_HSR1 PF01926.23 PXF48427.1 - 1.5e-07 31.5 0.3 2.7e-07 30.7 0.1 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PXF48427.1 - 2e-07 30.6 0.2 3.3e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 PXF48427.1 - 0.00052 20.6 0.0 0.00082 19.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 PXF48427.1 - 0.0013 18.2 0.7 0.0023 17.3 0.1 1.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family Histidinol_dh PF00815.20 PXF48427.1 - 0.0028 16.7 0.2 0.042 12.9 0.0 2.0 1 1 1 2 2 2 1 Histidinol dehydrogenase RsgA_GTPase PF03193.16 PXF48427.1 - 0.0042 17.0 0.2 0.0091 15.9 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PXF48427.1 - 0.0083 16.5 0.1 0.035 14.5 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 PXF48427.1 - 0.015 14.6 0.0 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin SRPRB PF09439.10 PXF48427.1 - 0.016 14.6 0.4 0.049 13.1 0.1 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PXF48427.1 - 0.018 15.1 4.3 0.025 14.6 1.0 2.4 2 1 1 3 3 3 0 Dynamin family AICARFT_IMPCHas PF01808.18 PXF48427.1 - 0.024 14.1 0.3 3.9 6.8 0.0 2.1 1 1 1 2 2 2 0 AICARFT/IMPCHase bienzyme DUF2075 PF09848.9 PXF48427.1 - 0.027 13.7 0.1 0.047 12.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PXF48427.1 - 0.031 14.6 0.2 0.073 13.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 PXF48427.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 PXF48427.1 - 0.039 13.5 0.2 0.096 12.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF5492 PF17596.2 PXF48427.1 - 0.04 14.2 0.0 4.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5492) AAA_29 PF13555.6 PXF48427.1 - 0.051 13.3 0.7 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 PXF48427.1 - 0.059 12.4 0.2 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 PXF48427.1 - 0.072 13.0 0.2 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 NTPase Gtr1_RagA PF04670.12 PXF48427.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.14 PXF48427.1 - 0.087 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 PXF48427.1 - 0.097 13.1 0.1 0.46 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 PXF48427.1 - 0.12 11.4 0.0 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain SMC_N PF02463.19 PXF48427.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AIG1 PF04548.16 PXF48428.1 - 2.4e-11 43.4 0.5 2.4e-11 43.4 0.5 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 PXF48428.1 - 2.1e-09 37.5 0.3 4.9e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF48428.1 - 6e-05 23.0 1.0 0.00016 21.6 1.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 PXF48428.1 - 8.6e-05 22.7 4.3 0.081 13.0 0.0 3.2 3 0 0 3 3 3 2 Dynamin family SRPRB PF09439.10 PXF48428.1 - 0.00019 20.9 0.3 0.00066 19.1 0.2 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 PXF48428.1 - 0.00041 19.8 0.3 0.01 15.2 0.1 2.4 2 1 0 2 2 2 1 FtsK/SpoIIIE family FeoB_N PF02421.18 PXF48428.1 - 0.0017 17.9 0.1 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 PXF48428.1 - 0.0028 17.0 0.1 0.03 13.6 0.1 2.4 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 PXF48428.1 - 0.0053 17.2 0.9 0.019 15.4 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 PXF48428.1 - 0.025 14.8 0.6 0.072 13.3 0.1 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 PXF48428.1 - 0.039 14.5 0.1 0.11 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Med19 PF10278.9 PXF48428.1 - 0.041 13.8 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ABC_tran PF00005.27 PXF48428.1 - 0.052 14.1 2.6 0.07 13.6 0.2 2.4 1 1 1 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 PXF48428.1 - 0.066 13.0 0.0 13 5.5 0.0 2.4 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 PXF48428.1 - 0.071 13.0 1.4 0.14 12.0 1.4 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 PXF48428.1 - 0.075 13.3 0.3 0.18 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PXF48428.1 - 0.081 12.4 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 PXF48428.1 - 0.082 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF48428.1 - 0.083 12.9 0.2 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 PXF48428.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.4 3 0 0 3 3 3 0 Guanylate kinase GTP_EFTU PF00009.27 PXF48428.1 - 0.13 11.8 0.9 12 5.4 0.0 2.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 PXF48428.1 - 0.28 11.3 1.8 0.45 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PXF48429.1 - 3.7e-09 36.7 0.0 5.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PXF48429.1 - 1.2e-07 31.2 0.0 2.8e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 PXF48429.1 - 0.00053 19.9 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PXF48429.1 - 0.00092 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 PXF48429.1 - 0.0048 17.1 0.0 0.012 15.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PXF48429.1 - 0.0061 17.1 0.1 0.012 16.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PXF48429.1 - 0.007 16.8 0.1 0.012 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 PXF48429.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NTPase Dynamin_N PF00350.23 PXF48429.1 - 0.0093 16.0 0.3 0.71 9.9 0.1 2.3 1 1 1 2 2 2 1 Dynamin family Guanylate_kin PF00625.21 PXF48429.1 - 0.054 13.2 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_22 PF13401.6 PXF48429.1 - 0.078 13.3 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 PXF48429.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 PXF48429.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PXF48429.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 PXF48429.1 - 0.2 10.9 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Septin WD40 PF00400.32 PXF48430.1 - 1.4e-14 54.3 10.3 0.098 13.6 0.4 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48430.1 - 5.5e-05 23.4 1.3 2.1 8.7 0.2 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF48430.1 - 0.054 12.5 0.3 0.21 10.5 0.2 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Di19_C PF14571.6 PXF48430.1 - 0.14 12.7 2.3 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal LTV PF04180.14 PXF48431.1 - 1.5e-17 64.5 16.0 7.9e-15 55.5 16.0 3.1 1 1 0 1 1 1 1 Low temperature viability protein Sec2p PF06428.11 PXF48432.1 - 0.051 13.5 0.2 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 PXF48432.1 - 0.069 13.8 1.0 0.22 12.2 1.0 1.8 1 0 0 1 1 1 0 SlyX DUF2559 PF10832.8 PXF48432.1 - 0.32 11.1 3.5 2.5 8.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) TrmO PF01980.16 PXF48433.1 - 3.8e-38 130.4 0.0 6e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 tRNA-methyltransferase O Mpv17_PMP22 PF04117.12 PXF48434.1 - 6.7e-19 67.9 0.7 6.7e-19 67.9 0.7 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family GTP_EFTU PF00009.27 PXF48436.1 - 2.4e-54 183.9 0.1 2.4e-54 183.9 0.1 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PXF48436.1 - 1.4e-18 66.7 0.0 3.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF48436.1 - 1.3e-07 31.9 0.1 3.9e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PXF48436.1 - 1.5e-06 28.2 0.0 4.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 PXF48436.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV Oxidored_q6 PF01058.22 PXF48437.1 - 3.5e-21 75.4 0.1 6.2e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF4826 PF16108.5 PXF48437.1 - 2.8 8.2 3.9 16 5.8 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4826) Na_H_Exchanger PF00999.21 PXF48438.1 - 3.7e-48 164.2 45.8 2.9e-31 108.6 21.7 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family EF-hand_1 PF00036.32 PXF48438.1 - 0.00012 21.4 0.1 0.00028 20.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PXF48438.1 - 0.00026 20.7 0.1 0.00073 19.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 PXF48438.1 - 0.0062 17.0 0.2 0.014 15.9 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PXF48438.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 EF hand UPF0182 PF03699.13 PXF48438.1 - 0.86 7.7 6.6 1.6 6.8 6.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Cornifin PF02389.15 PXF48439.1 - 0.62 10.3 31.5 0.5 10.6 29.8 1.7 1 1 0 1 1 1 0 Cornifin (SPRR) family Iso_dh PF00180.20 PXF48440.1 - 4.2e-93 312.3 0.0 5.2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Amidohydro_1 PF01979.20 PXF48442.1 - 6.2e-18 65.2 0.2 4e-10 39.5 0.1 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 PXF48442.1 - 2.5e-09 37.1 0.1 0.0029 17.1 0.1 2.7 3 0 0 3 3 3 2 Amidohydrolase family QIL1 PF15884.5 PXF48443.1 - 0.013 16.1 0.0 0.018 15.6 0.0 1.4 1 1 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 Mob1_phocein PF03637.17 PXF48444.1 - 2.3e-68 229.5 0.0 2.6e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family THDPS_N_2 PF14805.6 PXF48444.1 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Topoisom_I PF01028.20 PXF48444.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core MMR_HSR1 PF01926.23 PXF48445.1 - 1.9e-11 44.0 0.1 1.5e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 PXF48445.1 - 0.0012 18.1 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 PXF48445.1 - 0.0014 18.5 0.1 0.0052 16.7 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 PXF48445.1 - 0.0017 18.0 0.1 0.094 12.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PXF48445.1 - 0.0031 17.6 0.3 0.13 12.3 0.1 2.4 1 1 1 2 2 2 1 Dynamin family RNA_helicase PF00910.22 PXF48445.1 - 0.0033 17.8 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATP_bind_1 PF03029.17 PXF48445.1 - 0.0033 17.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein IIGP PF05049.13 PXF48445.1 - 0.0042 16.2 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Ploopntkinase3 PF18751.1 PXF48445.1 - 0.028 14.3 0.1 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 AAA_15 PF13175.6 PXF48445.1 - 0.03 14.1 0.2 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 PXF48445.1 - 0.058 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 PXF48445.1 - 0.068 12.7 0.2 0.23 11.0 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 PXF48445.1 - 0.079 13.2 0.0 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 PXF48445.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 PXF48445.1 - 0.2 11.9 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Spore_IV_A PF09547.10 PXF48445.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) DnaJ PF00226.31 PXF48446.1 - 0.0086 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1380 PF07128.12 PXF48448.1 - 0.043 14.0 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Spt5-NGN PF03439.13 PXF48448.1 - 0.082 12.8 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Na_Ca_ex PF01699.24 PXF48452.1 - 8.8e-57 191.3 43.3 8.6e-29 100.4 19.6 3.3 2 1 2 4 4 4 2 Sodium/calcium exchanger protein Ycf70 PF17382.2 PXF48452.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Hydrolase_6 PF13344.6 PXF48454.1 - 2.4e-29 101.4 0.0 3.7e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF48454.1 - 1.1e-20 73.5 0.0 2.8e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 PXF48454.1 - 3.2e-09 37.4 0.0 4.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PXF48454.1 - 7.6e-06 26.1 0.0 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 PXF48454.1 - 0.00035 20.2 0.0 0.00071 19.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 PXF48454.1 - 0.063 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF2608 PF11019.8 PXF48454.1 - 0.2 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) AAA PF00004.29 PXF48455.1 - 4.3e-89 295.7 0.0 9.5e-47 158.7 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF48455.1 - 2e-22 78.7 0.4 5.8e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 PXF48455.1 - 1.6e-14 53.9 0.0 1.2e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PXF48455.1 - 2.8e-12 47.4 1.8 0.00041 20.8 0.1 4.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 PXF48455.1 - 1.5e-10 41.2 0.6 0.0065 16.5 0.0 4.3 4 2 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PXF48455.1 - 2.6e-10 40.7 0.0 0.00039 20.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PXF48455.1 - 3.3e-09 37.1 0.0 0.0025 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PXF48455.1 - 3.6e-09 37.0 1.3 0.042 14.1 0.0 4.8 3 2 2 5 5 5 2 AAA domain TIP49 PF06068.13 PXF48455.1 - 8.3e-09 35.1 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 PXF48455.1 - 5.6e-07 29.5 0.1 0.034 13.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 PXF48455.1 - 1.3e-06 28.8 0.0 0.093 13.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 PXF48455.1 - 3.1e-06 26.7 2.0 0.032 13.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PXF48455.1 - 3.2e-06 27.1 0.0 0.094 12.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PXF48455.1 - 7.2e-06 26.1 0.0 0.035 14.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 PXF48455.1 - 9.2e-06 26.2 0.3 0.073 13.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PXF48455.1 - 9.7e-06 25.7 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PXF48455.1 - 1.5e-05 24.4 0.4 0.13 11.5 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin NACHT PF05729.12 PXF48455.1 - 1.6e-05 24.9 1.6 0.34 10.8 0.0 3.6 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 PXF48455.1 - 5.1e-05 23.6 0.3 0.21 11.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 PXF48455.1 - 5.4e-05 22.9 1.1 0.81 9.2 0.0 3.7 2 1 0 3 3 3 1 AAA domain Vps4_C PF09336.10 PXF48455.1 - 6e-05 23.0 0.0 0.31 11.1 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 PXF48455.1 - 6.7e-05 23.4 0.0 0.63 10.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.11 PXF48455.1 - 0.00011 22.0 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PXF48455.1 - 0.0002 20.8 0.1 1.2 8.5 0.0 3.2 3 0 0 3 3 3 2 KaiC Sigma54_activat PF00158.26 PXF48455.1 - 0.00051 19.8 0.1 0.42 10.3 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.22 PXF48455.1 - 0.00082 18.6 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase_2 PF01637.18 PXF48455.1 - 0.0021 18.0 0.1 0.57 10.1 0.0 3.2 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 PXF48455.1 - 0.0025 17.6 0.1 2.3 7.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 PXF48455.1 - 0.0028 17.4 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 PXF48455.1 - 0.0031 17.9 0.2 1.2 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PXF48455.1 - 0.0044 16.6 0.0 1.4 8.4 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region PhoH PF02562.16 PXF48455.1 - 0.0049 16.3 0.7 2.1 7.7 0.1 2.7 2 0 0 2 2 2 1 PhoH-like protein Bac_DnaA PF00308.18 PXF48455.1 - 0.0052 16.7 0.0 23 4.7 0.0 3.5 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_11 PF13086.6 PXF48455.1 - 0.012 15.5 2.1 6.8 6.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 PXF48455.1 - 0.021 14.0 0.0 3.5 6.7 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 PXF48455.1 - 0.032 13.3 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 PXF48455.1 - 0.046 13.8 0.1 1.9 8.6 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 PXF48455.1 - 0.067 13.1 0.1 7.8 6.4 0.0 2.6 2 1 0 2 2 2 0 NTPase PduV-EutP PF10662.9 PXF48455.1 - 0.2 11.4 0.0 30 4.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 PXF48455.1 - 0.21 10.8 0.6 26 3.9 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PXF48455.1 - 0.28 11.5 1.1 32 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain tRNA_m1G_MT PF01746.21 PXF48456.1 - 0.039 13.7 0.0 0.043 13.5 0.0 1.0 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Aminotran_1_2 PF00155.21 PXF48456.1 - 0.095 11.9 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfotransfer_3 PF13469.6 PXF48457.1 - 5.1e-06 27.0 0.2 0.023 15.1 0.0 2.6 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PXF48457.1 - 0.0031 17.0 0.0 0.0076 15.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase domain DUF1294 PF06961.13 PXF48457.1 - 0.015 15.5 0.2 0.037 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) YtfJ_HI0045 PF09695.10 PXF48457.1 - 0.13 11.9 0.1 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) AFG1_ATPase PF03969.16 PXF48459.1 - 2.5e-57 194.4 0.2 3.2e-53 180.9 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 PXF48459.1 - 0.0002 21.8 0.0 0.0039 17.6 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PXF48459.1 - 0.087 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RETICULATA-like PF11891.8 PXF48460.1 - 3e-36 124.9 0.0 5.8e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related Fibrillarin PF01269.17 PXF48461.1 - 4.7e-103 343.2 0.0 5.5e-103 343.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 PXF48461.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 PXF48461.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 PXF48461.1 - 0.079 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PXF48461.1 - 0.14 12.3 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CHCH PF06747.13 PXF48462.1 - 2.2e-06 27.7 3.5 3.1e-06 27.2 3.5 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 PXF48462.1 - 6.6e-05 23.1 0.5 8.3e-05 22.7 0.5 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 PXF48462.1 - 0.0045 17.0 2.7 0.0071 16.3 2.7 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 PXF48462.1 - 0.016 15.2 1.2 0.028 14.4 1.2 1.4 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HTH_5 PF01022.20 PXF48462.1 - 0.089 12.7 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family UCR_hinge PF02320.16 PXF48462.1 - 0.12 12.6 2.2 4.9 7.4 0.6 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein RRM_1 PF00076.22 PXF48463.1 - 9e-13 47.9 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 PXF48463.1 - 0.00034 21.2 1.7 1.8 9.6 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF3678 PF12435.8 PXF48463.1 - 0.73 9.3 5.3 2 7.9 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Trypsin PF00089.26 PXF48464.1 - 1.3e-29 103.6 0.1 1.6e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF48464.1 - 0.0003 21.7 0.2 0.00052 20.9 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF48465.1 - 1.3e-40 139.6 0.1 1.6e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF48465.1 - 4.3e-05 24.4 0.1 8.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain TPPK_C PF12555.8 PXF48465.1 - 0.087 12.9 0.8 0.16 12.0 0.8 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal zf-H2C2_2 PF13465.6 PXF48466.1 - 5.3e-15 55.1 11.4 3.1e-07 30.5 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 PXF48466.1 - 6.5e-06 26.3 15.2 0.0035 17.7 1.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF48466.1 - 0.00013 22.5 15.5 0.11 13.4 0.7 3.6 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PXF48466.1 - 0.0012 19.1 8.0 0.0024 18.1 8.0 1.5 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-TRAF PF02176.18 PXF48466.1 - 0.0073 17.0 7.7 0.58 10.9 1.1 2.1 1 1 1 2 2 2 2 TRAF-type zinc finger zf-H2C2_5 PF13909.6 PXF48466.1 - 0.022 14.5 1.5 0.022 14.5 1.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf_Hakai PF18408.1 PXF48466.1 - 0.049 13.3 0.2 0.049 13.3 0.2 2.9 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-C2H2_jaz PF12171.8 PXF48466.1 - 0.15 12.4 7.9 0.2 12.0 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding UBX PF00789.20 PXF48469.1 - 2e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PXF48469.1 - 3.1e-09 36.5 0.2 7.2e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 PXF48469.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Menin PF05053.13 PXF48469.1 - 0.79 8.0 2.7 1.1 7.5 2.7 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 PXF48470.1 - 1.2e-09 38.0 0.0 3.8e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 PXF48470.1 - 9.5e-09 34.8 0.9 0.019 15.2 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Pkinase_Tyr PF07714.17 PXF48470.1 - 1.4e-05 24.6 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 PXF48470.1 - 3e-05 24.1 0.4 0.0005 20.1 0.0 2.5 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 PXF48470.1 - 5.9e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 PXF48470.1 - 0.0004 20.7 1.7 0.0044 17.4 0.2 2.9 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PXF48470.1 - 0.0013 19.2 0.6 0.091 13.3 0.0 3.2 2 1 1 3 3 3 1 HEAT-like repeat CLASP_N PF12348.8 PXF48470.1 - 0.073 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 CLASP N terminal Endomucin PF07010.12 PXF48470.1 - 1 9.3 9.0 2.4 8.1 9.0 1.5 1 0 0 1 1 1 0 Endomucin FKBP_C PF00254.28 PXF48471.1 - 2.1e-19 69.6 0.0 3.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PP28 PF10252.9 PXF48471.1 - 0.001 19.5 3.9 0.001 19.5 3.9 2.2 1 1 1 2 2 2 1 Casein kinase substrate phosphoprotein PP28 CbiX PF01903.17 PXF48472.1 - 2.3e-28 98.6 0.0 2.9e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 PXF48472.1 - 4.3e-08 32.8 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 PXF48472.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase IMPDH PF00478.25 PXF48473.1 - 5.5e-133 443.2 1.9 6.3e-133 443.0 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 PXF48473.1 - 8.8e-13 48.5 0.1 5.9e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 PXF48473.1 - 2.5e-09 37.0 0.7 3.1e-05 23.5 0.3 2.7 2 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 PXF48473.1 - 1e-08 34.6 0.7 7.3e-08 31.8 0.6 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.14 PXF48473.1 - 0.00045 19.5 0.3 0.0012 18.1 0.3 1.7 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.19 PXF48473.1 - 0.0042 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 KDPG and KHG aldolase His_biosynth PF00977.21 PXF48473.1 - 0.0045 16.5 0.3 0.037 13.5 0.3 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein QRPTase_C PF01729.19 PXF48473.1 - 0.028 14.2 0.2 0.19 11.5 0.0 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 PXF48473.1 - 0.041 13.2 0.5 0.13 11.6 0.2 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 PXF48473.1 - 0.11 11.6 2.2 0.27 10.4 0.3 2.1 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase Reticulon PF02453.17 PXF48474.1 - 8.6e-26 90.8 1.4 1.1e-25 90.4 1.4 1.1 1 0 0 1 1 1 1 Reticulon DUF92 PF01940.16 PXF48474.1 - 0.014 14.9 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF92 PRT_C PF08372.10 PXF48474.1 - 0.017 14.9 0.1 0.017 14.9 0.1 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal HAD_SAK_1 PF10307.9 PXF48475.1 - 7.7e-09 35.7 0.0 1.4e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins HAD PF12710.7 PXF48475.1 - 0.00099 19.6 0.1 1.4 9.2 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase LdpA_C PF12617.8 PXF48476.1 - 2.8e-46 157.5 0.0 4.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Iron-Sulfur binding protein C terminal Fer4_7 PF12838.7 PXF48476.1 - 8.3e-06 26.3 6.4 0.0031 18.0 2.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PXF48476.1 - 1.5e-05 24.8 13.5 0.018 15.1 4.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 PXF48476.1 - 4.6e-05 23.1 15.3 0.00035 20.3 5.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 PXF48476.1 - 0.0021 19.0 11.1 0.077 13.9 2.6 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 PXF48476.1 - 0.0025 17.8 13.1 0.054 13.6 4.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 PXF48476.1 - 0.004 17.6 4.2 0.025 15.0 0.8 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PXF48476.1 - 0.0096 16.0 3.3 0.0096 16.0 3.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 PXF48476.1 - 0.017 15.3 13.1 0.064 13.4 3.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 PXF48476.1 - 0.024 15.1 11.3 0.031 14.8 0.8 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 PXF48476.1 - 0.21 12.2 7.9 0.11 13.1 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 PXF48476.1 - 0.28 11.4 16.8 0.045 13.9 11.6 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 PXF48476.1 - 3.7 8.7 16.2 0.14 13.2 4.0 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain Golgin_A5 PF09787.9 PXF48477.1 - 1.9e-13 50.6 0.5 1.9e-13 50.6 0.5 5.0 1 1 3 5 5 5 2 Golgin subfamily A member 5 HALZ PF02183.18 PXF48477.1 - 0.00031 20.9 1.5 0.00031 20.9 1.5 4.3 4 0 0 4 4 4 2 Homeobox associated leucine zipper Fungal_TACC PF12709.7 PXF48477.1 - 1.5 9.3 23.4 0.039 14.4 4.0 4.6 4 0 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins MA3 PF02847.17 PXF48478.1 - 9e-13 48.2 0.4 1.9e-12 47.1 0.4 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 PXF48478.1 - 7.8e-10 38.7 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain DUF442 PF04273.13 PXF48478.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) ABC_tran PF00005.27 PXF48479.1 - 1.4e-19 71.0 0.0 2.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF48479.1 - 5.5e-11 42.8 0.4 6.2e-05 23.0 0.5 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PXF48479.1 - 4.1e-07 29.7 0.2 0.0014 18.2 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PXF48479.1 - 0.0011 18.6 0.3 0.0036 17.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF48479.1 - 0.0033 17.2 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 PXF48479.1 - 0.0057 17.2 0.0 0.0079 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PXF48479.1 - 0.0091 16.3 0.0 0.048 13.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF48479.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 PXF48479.1 - 0.032 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PXF48479.1 - 0.13 12.3 0.1 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PXF48479.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 PXF48479.1 - 0.14 12.4 0.5 1.5 9.1 0.5 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 PXF48479.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain Creatininase PF02633.14 PXF48481.1 - 1.2e-46 159.2 0.0 1.3e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase DEAD PF00270.29 PXF48482.1 - 5.5e-41 140.2 0.0 9.1e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48482.1 - 1.7e-29 102.4 0.0 8.2e-27 93.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48482.1 - 9.6e-05 22.4 0.0 9.6e-05 22.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PXF48482.1 - 0.043 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 PXF48482.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain CDK2AP PF09806.9 PXF48482.1 - 2.8 7.9 7.0 38 4.2 7.3 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Nop14 PF04147.12 PXF48482.1 - 3.2 5.8 23.6 6 4.9 23.6 1.5 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 PXF48482.1 - 4 7.4 9.7 11 6.0 9.7 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PQ-loop PF04193.14 PXF48483.1 - 8.1e-27 92.8 2.1 1.8e-12 46.8 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat PP2C PF00481.21 PXF48484.1 - 1.9e-35 122.7 0.0 2.5e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF48484.1 - 5.4e-13 49.1 0.6 7.6e-13 48.6 0.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PXF48484.1 - 1.8e-08 34.5 1.6 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Voltage_CLC PF00654.20 PXF48485.1 - 9.8e-63 212.5 30.2 9.8e-63 212.5 30.2 1.6 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 PXF48485.1 - 0.091 13.2 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 CBS domain Inositol_P PF00459.25 PXF48488.1 - 5.8e-47 160.5 0.0 1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1732 PF08340.11 PXF48488.1 - 4.1e-26 90.8 0.5 7.7e-26 89.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) YicC_N PF03755.13 PXF48488.1 - 5.2e-26 91.9 0.1 1.2e-25 90.7 0.1 1.7 1 0 0 1 1 1 1 YicC-like family, N-terminal region SIR2 PF02146.17 PXF48489.1 - 2.4e-27 96.0 0.0 3.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PXF48489.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Sulfotransfer_2 PF03567.14 PXF48490.1 - 2.2e-27 96.6 0.9 2.7e-27 96.3 0.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family SH2_2 PF14633.6 PXF48492.1 - 1e-36 126.4 0.0 1.9e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 PXF48492.1 - 2.6e-13 50.2 0.0 6.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 PXF48492.1 - 6.1e-10 39.6 17.7 6.1e-10 39.6 17.7 6.3 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.6 PXF48492.1 - 1.2e-09 38.6 0.5 1.1e-07 32.2 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 PXF48492.1 - 0.00084 20.2 0.1 0.008 17.1 0.1 2.9 1 1 0 1 1 1 1 HHH domain CMD PF02627.20 PXF48492.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF4410 PF14366.6 PXF48492.1 - 0.2 11.6 1.4 6.9 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4410) Lactamase_B_2 PF12706.7 PXF48493.1 - 6.1e-21 74.9 0.0 1.7e-19 70.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PXF48493.1 - 1.6e-09 37.9 0.1 3.8e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SPX PF03105.19 PXF48493.1 - 1.6 8.5 15.8 2.4 8.0 15.8 1.3 1 0 0 1 1 1 0 SPX domain SUKH-3 PF14433.6 PXF48494.1 - 0.055 13.9 0.0 0.065 13.7 0.0 1.1 1 0 0 1 1 1 0 SUKH-3 immunity protein Mpv17_PMP22 PF04117.12 PXF48497.1 - 1.4e-17 63.7 1.2 1.4e-17 63.7 1.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family zf-C2H2_4 PF13894.6 PXF48498.1 - 0.0075 17.0 8.1 0.63 11.0 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DUF629 PF04780.12 PXF48498.1 - 0.011 14.2 0.1 0.45 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 PXF48498.1 - 0.041 14.4 8.5 1 9.9 1.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 PXF48498.1 - 0.52 11.0 4.1 13 6.5 0.0 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats TFIIA PF03153.13 PXF48498.1 - 9.5 6.1 15.1 13 5.6 15.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypsin_2 PF13365.6 PXF48499.1 - 5.1e-28 98.9 0.4 1.2e-27 97.6 0.2 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF48499.1 - 5.7e-15 55.7 0.1 8.7e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 PXF48499.1 - 1.8e-10 40.5 0.0 4.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PXF48499.1 - 5e-08 33.2 0.1 1.3e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PXF48499.1 - 5e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 PXF48499.1 - 0.031 14.0 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 PXF48499.1 - 0.13 10.9 0.9 0.6 8.7 0.1 1.9 2 0 0 2 2 2 0 Peptidase S46 DUF3372 PF11852.8 PXF48499.1 - 0.15 11.6 0.5 0.85 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) Tricorn_PDZ PF14685.6 PXF48499.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF31 PF01732.16 PXF48499.1 - 0.24 10.9 3.3 2.3 7.7 0.5 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) ThiC_Rad_SAM PF01964.18 PXF48500.1 - 2.2e-198 659.2 0.0 2.5e-198 659.0 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 PXF48500.1 - 1.2e-06 28.2 0.0 4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 ThiC-associated domain AMPK1_CBM PF16561.5 PXF48501.1 - 2.3e-20 72.6 1.6 2.7e-20 72.4 0.1 1.8 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Glyco_trans_2_3 PF13632.6 PXF48501.1 - 1.2e-18 67.8 0.2 1.2e-18 67.8 0.2 3.3 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 PXF48501.1 - 3.4e-17 62.3 12.5 9.4e-09 34.3 0.2 4.6 2 1 1 3 3 3 2 Cellulose synthase Glyco_tranf_2_3 PF13641.6 PXF48501.1 - 1.8e-15 57.5 0.1 7e-12 45.7 0.1 3.0 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF48501.1 - 1.8e-13 50.7 0.1 2.6e-07 30.6 0.1 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PXF48501.1 - 6.2e-08 32.3 0.4 5.5e-06 26.0 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 CBM53 PF16760.5 PXF48501.1 - 0.051 14.2 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Cellulose_synt PF03552.14 PXF48502.1 - 1.5e-17 63.5 16.2 5.9e-08 31.7 0.2 4.6 3 1 1 4 4 4 3 Cellulose synthase AMPK1_CBM PF16561.5 PXF48502.1 - 1.7e-15 56.9 0.6 4.1e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Glyco_trans_2_3 PF13632.6 PXF48502.1 - 3e-15 56.7 16.5 4.9e-15 56.0 9.9 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PXF48502.1 - 3.5e-14 53.3 1.6 6.6e-12 45.8 0.4 3.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF48502.1 - 1.2e-12 47.9 1.0 1.1e-07 31.9 0.6 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PXF48502.1 - 8.4e-07 28.6 0.9 0.00056 19.4 0.1 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 21 PerB PF06590.11 PXF48502.1 - 0.12 12.9 0.0 0.44 11.1 0.0 1.9 2 0 0 2 2 2 0 PerB protein RPN7 PF10602.9 PXF48503.1 - 1.5e-53 181.1 2.0 2.4e-53 180.4 2.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PXF48503.1 - 6.1e-11 42.8 0.0 1.5e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain ComR_TPR PF18710.1 PXF48503.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 ComR tetratricopeptide TPR_7 PF13176.6 PXF48503.1 - 0.11 12.5 0.0 3.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIS_C PF01096.18 PXF48504.1 - 5.5e-11 42.1 2.5 6.6e-10 38.7 0.1 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 PXF48504.1 - 0.0032 17.5 1.5 10 6.3 0.0 3.2 3 0 0 3 3 3 1 Zinc ribbon domain DPCD PF14913.6 PXF48504.1 - 0.028 13.8 0.4 0.034 13.5 0.4 1.1 1 0 0 1 1 1 0 DPCD protein family Zn_ribbon_SprT PF17283.2 PXF48504.1 - 0.038 13.9 4.9 13 5.8 0.0 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-ZPR1 PF03367.13 PXF48504.1 - 0.038 13.8 0.9 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain TF_Zn_Ribbon PF08271.12 PXF48504.1 - 0.056 13.0 4.8 14 5.3 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 PXF48504.1 - 0.059 13.3 3.8 2.5 8.1 0.1 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-3CxxC PF13695.6 PXF48504.1 - 0.095 13.2 2.8 18 5.9 1.3 2.7 2 1 0 2 2 2 0 Zinc-binding domain zinc_ribbon_10 PF10058.9 PXF48504.1 - 0.12 12.1 5.0 3.6 7.4 1.1 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-TFIIB PF13453.6 PXF48504.1 - 0.18 11.2 4.1 0.17 11.2 1.2 2.2 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-B_box PF00643.24 PXF48504.1 - 0.18 12.0 4.8 8.2 6.7 0.2 3.1 3 0 0 3 3 3 0 B-box zinc finger RNA_POL_M_15KD PF02150.16 PXF48504.1 - 0.51 10.2 9.7 0.31 11.0 1.0 3.7 3 1 0 3 3 3 0 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 PXF48504.1 - 0.64 10.0 6.6 14 5.7 0.3 3.6 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Zn_Tnp_IS1 PF03811.13 PXF48504.1 - 0.74 9.6 0.0 0.74 9.6 0.0 2.5 3 0 0 3 3 3 0 InsA N-terminal domain zf-ribbon_3 PF13248.6 PXF48504.1 - 0.89 9.1 7.5 4.9 6.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 PXF48504.1 - 1.5 8.9 4.6 6 6.9 1.0 2.5 1 1 1 2 2 2 0 CpXC protein zf_Rg PF17915.1 PXF48504.1 - 1.5 8.3 4.3 3.1 7.3 0.1 2.8 3 0 0 3 3 3 0 Reverse gyrase zinc finger Cnd3 PF12719.7 PXF48505.1 - 5.7e-50 170.2 1.3 1.2e-48 165.9 0.6 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 PXF48505.1 - 1.2e-07 31.3 13.3 0.51 10.8 0.1 7.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 PXF48505.1 - 3.6e-06 27.3 23.8 0.0019 18.5 0.2 6.2 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 PXF48505.1 - 3.6e-05 23.9 7.8 1.3 9.0 0.0 5.2 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 PXF48505.1 - 0.00058 19.1 2.2 0.02 14.0 0.2 2.9 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) PaaX PF07848.12 PXF48505.1 - 0.0084 16.3 0.3 0.049 13.9 0.0 2.4 3 0 0 3 3 2 1 PaaX-like protein HEAT_EZ PF13513.6 PXF48505.1 - 0.026 15.0 13.1 0.16 12.5 0.1 5.0 5 0 0 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 PXF48505.1 - 0.037 13.6 1.7 10 5.6 0.0 3.6 2 1 1 3 3 3 0 CLASP N terminal Cohesin_HEAT PF12765.7 PXF48505.1 - 1.5 9.2 12.4 3.1 8.2 0.2 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SRP-alpha_N PF04086.13 PXF48505.1 - 1.8 8.4 11.0 2.7 7.9 11.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TrbI_Ftype PF09677.10 PXF48505.1 - 2.5 8.4 5.5 69 3.8 0.2 3.6 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) Methyltr_RsmB-F PF01189.17 PXF48506.1 - 5.1e-42 143.8 0.0 1.9e-40 138.7 0.0 2.5 3 0 0 3 3 3 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PXF48506.1 - 7e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase bHLH-MYC_N PF14215.6 PXF48507.1 - 3.2e-09 37.3 0.2 5.8e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.6 PXF48507.1 - 1.1e-06 29.0 0.0 2.7e-06 27.7 0.0 1.7 1 1 1 2 2 2 1 GAF domain GAF PF01590.26 PXF48507.1 - 0.00017 22.2 0.0 0.00034 21.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain HLH PF00010.26 PXF48507.1 - 0.0024 17.8 1.5 0.0095 15.9 1.5 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1995 PF09353.10 PXF48508.1 - 1.3e-22 80.8 0.0 1.8e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Pkinase PF00069.25 PXF48509.1 - 3e-59 200.6 0.0 4.6e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48509.1 - 2.7e-43 148.1 0.0 4.1e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 PXF48509.1 - 2e-15 56.9 0.1 1.7e-08 34.7 0.2 2.9 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 PXF48509.1 - 0.00014 20.8 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PXF48509.1 - 0.021 13.8 0.1 0.046 12.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PXF48509.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Porin_3 PF01459.22 PXF48510.1 - 2.4e-36 125.6 5.4 3e-36 125.3 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin LIM_bind PF01803.16 PXF48511.1 - 1.2e-23 83.9 0.1 3e-23 82.6 0.1 1.7 1 1 0 1 1 1 1 LIM-domain binding protein Ribosomal_60s PF00428.19 PXF48511.1 - 0.0066 17.0 7.6 0.028 15.0 7.6 2.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PRA1 PF03208.19 PXF48512.1 - 1.9e-22 79.4 9.1 2.6e-22 79.0 9.1 1.2 1 0 0 1 1 1 1 PRA1 family protein CAAX_1 PF15895.5 PXF48512.1 - 0.018 15.0 0.2 0.032 14.1 0.1 1.4 1 1 0 1 1 1 0 CAAX box cerebral protein 1 SUR7 PF06687.12 PXF48512.1 - 0.1 12.2 2.6 0.13 11.8 2.6 1.2 1 0 0 1 1 1 0 SUR7/PalI family E1-E2_ATPase PF00122.20 PXF48512.1 - 2.7 7.5 7.2 2.8 7.4 2.2 2.3 1 1 0 2 2 2 0 E1-E2 ATPase zf-C2H2 PF00096.26 PXF48513.1 - 1.1e-07 31.9 6.2 0.0018 18.6 1.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF48513.1 - 2.4e-05 24.5 5.6 3.2e-05 24.1 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF48513.1 - 7.8e-05 23.2 5.8 0.13 13.2 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PXF48513.1 - 0.0084 16.4 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon SMN PF06003.12 PXF48513.1 - 0.039 13.2 1.1 0.066 12.5 1.1 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) IBR PF01485.21 PXF48513.1 - 0.045 14.0 0.5 0.045 14.0 0.5 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 PXF48513.1 - 0.093 13.0 0.7 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2057 PF09829.9 PXF48513.1 - 1.5 8.9 5.0 2.6 8.2 5.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Coatomer_WDAD PF04053.14 PXF48515.1 - 5.7e-151 503.5 0.0 2e-150 501.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 PXF48515.1 - 3.7e-38 128.8 11.4 1.2e-08 35.5 0.3 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48515.1 - 9.1e-07 29.1 0.5 2.2 8.7 0.0 5.9 3 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF48515.1 - 0.015 14.6 0.0 0.66 9.2 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 PXF48515.1 - 0.033 12.9 0.2 4.7 5.7 0.0 2.3 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF1668 PF07893.13 PXF48515.1 - 0.38 10.1 2.7 14 4.9 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) Coilin_N PF15862.5 PXF48516.1 - 9e-11 41.7 0.0 9e-11 41.7 0.0 5.8 7 1 0 7 7 7 1 Coilin N-terminus Glutaredoxin PF00462.24 PXF48517.1 - 6.1e-18 64.8 0.0 1.3e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 PXF48517.1 - 0.00099 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pribosyltran_N PF13793.6 PXF48518.1 - 2.8e-42 143.3 0.0 5.3e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PXF48518.1 - 1.9e-22 80.2 0.2 6.3e-22 78.5 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PXF48518.1 - 9.3e-17 61.0 0.6 2.3e-16 59.7 0.6 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PXF48518.1 - 7.7e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DNA_gyraseB PF00204.25 PXF48519.1 - 6.6e-53 178.8 0.0 1e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 PXF48519.1 - 1.2e-26 92.7 0.1 2.3e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 PXF48519.1 - 1e-21 77.5 0.1 2.1e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PXF48519.1 - 1.7e-17 63.5 0.0 3.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 PXF48519.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Beta-Casp PF10996.8 PXF48520.1 - 3.2e-29 101.4 0.0 6.5e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.8 PXF48520.1 - 2.9e-28 98.9 0.0 1.4e-20 73.8 0.0 2.3 1 1 1 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_6 PF16661.5 PXF48520.1 - 1.2e-19 70.5 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF48520.1 - 7.7e-19 68.5 0.0 4.9e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 PXF48520.1 - 1.6e-13 50.4 0.1 3.2e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 PXF48520.1 - 2.6e-10 40.1 0.0 6.2e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PXF48520.1 - 1.3e-07 31.6 0.0 1.2e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 PXF48520.1 - 0.037 13.2 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative beta-lactamase-like family SpoU_methylase PF00588.19 PXF48521.1 - 6e-23 81.6 0.0 8.5e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Ribul_P_3_epim PF00834.19 PXF48522.1 - 1.9e-68 229.8 0.0 6.7e-34 117.0 0.0 2.0 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family IMPDH PF00478.25 PXF48522.1 - 0.0041 16.2 0.2 0.044 12.8 0.1 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 PXF48522.1 - 0.0056 16.2 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein OMPdecase PF00215.24 PXF48522.1 - 0.028 14.0 0.1 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.17 PXF48522.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 PcrB family QRPTase_C PF01729.19 PXF48522.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Thioredoxin PF00085.20 PXF48523.1 - 1.8e-21 76.0 0.0 2e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Pho88 PF10032.9 PXF48523.1 - 2.3e-13 49.8 0.0 3.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) AhpC-TSA PF00578.21 PXF48523.1 - 1.3e-06 28.4 0.1 3.5e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PXF48523.1 - 2.7e-06 27.8 0.1 1.9e-05 25.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PXF48523.1 - 0.00012 21.6 0.0 0.00012 21.6 0.0 2.4 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PXF48523.1 - 0.00064 20.0 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 PXF48523.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PXF48523.1 - 0.0015 18.7 0.2 0.0095 16.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like DUF2208 PF09973.9 PXF48523.1 - 0.0038 16.9 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) Redoxin PF08534.10 PXF48523.1 - 0.0046 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin T4_deiodinase PF00837.17 PXF48523.1 - 0.015 14.6 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Iodothyronine deiodinase DUF5042 PF16445.5 PXF48523.1 - 0.018 13.5 0.0 0.027 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) DSBA PF01323.20 PXF48523.1 - 0.046 13.5 0.0 0.44 10.3 0.0 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Mannosyl_trans4 PF15971.5 PXF48523.1 - 0.073 12.9 0.6 0.073 12.9 0.6 1.8 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase TraF PF13728.6 PXF48523.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein UbiA PF01040.18 PXF48523.1 - 0.49 9.6 14.6 1.6 8.0 7.0 2.2 1 1 1 2 2 2 0 UbiA prenyltransferase family NDUF_B12 PF08122.12 PXF48523.1 - 1.3 9.1 9.2 0.81 9.8 3.9 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4131 PF13567.6 PXF48523.1 - 3.2 7.4 6.6 3.8 7.1 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UQ_con PF00179.26 PXF48524.1 - 4.4e-63 211.1 0.0 3.3e-32 111.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 PXF48524.1 - 5.6e-06 26.2 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 1 UEV domain PIN_6 PF17146.4 PXF48525.1 - 2.2e-22 79.4 2.0 3.6e-21 75.5 0.1 3.3 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 PXF48525.1 - 2.5e-20 72.4 1.4 4.8e-20 71.5 1.4 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 PXF48525.1 - 0.055 13.5 0.4 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 PXF48525.1 - 0.064 12.9 2.3 5.6 6.7 0.7 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 PXF48525.1 - 0.79 9.5 3.6 2 8.2 3.6 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 PXF48525.1 - 4.4 7.6 10.0 13 6.2 1.3 2.8 2 0 0 2 2 2 0 Ribosomal L32p protein family Prefoldin_2 PF01920.20 PXF48526.1 - 1.4e-17 63.6 8.5 1.4e-17 63.6 8.5 1.4 1 1 0 1 1 1 1 Prefoldin subunit SWI-SNF_Ssr4 PF08549.10 PXF48526.1 - 0.024 13.3 3.8 0.024 13.3 3.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) APG6_N PF17675.1 PXF48526.1 - 0.033 14.7 11.5 0.35 11.4 11.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region AFOR_N PF02730.15 PXF48526.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 1 1 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DHR10 PF18595.1 PXF48526.1 - 0.13 12.3 14.0 0.19 11.8 3.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 PXF48526.1 - 0.21 11.7 8.2 2.4 8.3 8.2 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 PXF48526.1 - 4.1 7.7 9.2 3.5 7.9 0.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UQ_con PF00179.26 PXF48528.1 - 2.8e-44 150.2 0.0 3.1e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF48528.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF924 PF06041.11 PXF48529.1 - 2.3e-54 184.3 1.0 2.9e-54 183.9 1.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Pox_D5 PF03288.16 PXF48530.1 - 0.048 14.2 0.7 1.7 9.2 0.1 2.8 2 0 0 2 2 2 0 Poxvirus D5 protein-like CTK3 PF12243.8 PXF48530.1 - 0.1 12.6 0.1 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 CHD5 PF04420.14 PXF48530.1 - 0.21 11.5 1.9 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 CHD5-like protein DUF1690 PF07956.11 PXF48530.1 - 0.59 10.5 8.5 0.15 12.5 3.0 2.6 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Snapin_Pallidin PF14712.6 PXF48530.1 - 1.5 9.3 6.8 49 4.4 5.9 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 PXF48530.1 - 1.6 8.2 5.3 4.2 6.8 0.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit RRM_1 PF00076.22 PXF48531.1 - 4.6e-40 135.3 0.0 6.7e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PXF48531.1 - 0.00056 19.9 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 PXF48531.1 - 0.011 15.9 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 PXF48531.1 - 0.094 12.7 0.0 0.93 9.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 PXF48532.1 - 8.8e-61 201.9 3.2 1.5e-19 69.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 PXF48533.1 - 9.9e-14 51.4 4.8 1.3e-13 51.0 4.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF48533.1 - 0.00027 21.1 10.1 0.00027 21.1 10.1 1.9 2 0 0 2 2 2 1 EamA-like transporter family ANAPC4_WD40 PF12894.7 PXF48534.1 - 3.1e-09 37.0 0.0 0.043 14.1 0.0 6.6 5 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF48534.1 - 1.6e-05 25.6 10.2 14 6.7 0.1 7.4 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PXF48534.1 - 0.12 11.3 0.0 5.4 5.9 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nore1-SARAH PF16517.5 PXF48535.1 - 0.048 13.6 0.4 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain TrbC PF04956.13 PXF48535.1 - 0.1 12.9 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF4134 PF13572.6 PXF48535.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) HD_4 PF13328.6 PXF48536.1 - 8.6e-19 67.8 0.1 1.5e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.22 PXF48536.1 - 2.5e-06 27.7 0.5 5.3e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 HD domain DUF5399 PF17377.2 PXF48536.1 - 0.00034 20.4 0.4 0.00055 19.8 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5399) DUF4083 PF13314.6 PXF48536.1 - 0.068 13.1 0.2 0.8 9.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) RL10P_insert PF17777.1 PXF48537.1 - 1.6e-20 72.9 0.4 3.9e-20 71.6 0.3 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 PXF48537.1 - 1.2e-19 70.3 1.2 2e-19 69.6 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 PXF48537.1 - 7.6e-13 48.9 14.3 1.4e-12 48.0 13.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein ATP_bind_1 PF03029.17 PXF48538.1 - 1.3e-79 267.4 0.1 1.5e-79 267.2 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PXF48538.1 - 0.0066 17.0 0.0 0.014 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 PXF48538.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 PXF48538.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PXF48538.1 - 0.032 14.6 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 PXF48538.1 - 0.048 13.3 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 PXF48538.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 PXF48538.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 PXF48538.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.20 PXF48538.1 - 0.15 11.2 0.0 0.58 9.3 0.0 2.0 1 1 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.22 PXF48538.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 PXF48538.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PXF48538.1 - 0.21 11.5 0.0 16 5.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3754 PF12576.8 PXF48540.1 - 2.3e-06 27.6 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) CHCH PF06747.13 PXF48541.1 - 4.1e-05 23.6 2.0 6e-05 23.1 2.0 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 PXF48541.1 - 0.0022 18.0 1.7 0.0047 16.9 1.7 1.5 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 PXF48541.1 - 0.1 13.0 0.9 0.18 12.2 0.1 1.7 1 1 1 2 2 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF2076 PF09849.9 PXF48541.1 - 0.39 10.7 19.1 0.15 12.1 15.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Rdx PF10262.9 PXF48542.1 - 5.7e-30 103.3 0.0 6.7e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 Rdx family Mt_ATP-synt_D PF05873.12 PXF48543.1 - 8.4e-11 41.9 3.1 1.1e-10 41.6 3.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T4SS PF07996.11 PXF48543.1 - 0.00021 21.8 0.0 0.00033 21.1 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion system proteins DASH_Spc19 PF08287.11 PXF48543.1 - 0.0089 15.9 0.2 0.016 15.1 0.2 1.4 1 0 0 1 1 1 1 Spc19 RP-C PF03428.13 PXF48543.1 - 0.032 13.9 0.4 0.068 12.8 0.4 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain SBDS_C PF09377.10 PXF48543.1 - 0.062 13.3 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain PdaC PF13739.6 PXF48543.1 - 0.12 13.3 1.1 0.32 12.0 0.3 2.2 2 1 0 2 2 2 0 Deacetylase PdaC F-box PF00646.33 PXF48544.1 - 0.0014 18.4 0.5 0.01 15.7 0.5 2.6 1 1 0 1 1 1 1 F-box domain DUF2960 PF11173.8 PXF48544.1 - 0.12 12.9 0.2 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) GTP_EFTU PF00009.27 PXF48545.1 - 3.1e-37 128.0 0.0 4.9e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 PXF48545.1 - 1e-28 100.3 5.8 2.2e-28 99.3 5.8 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 PXF48545.1 - 6.4e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 PXF48545.1 - 2.7e-14 53.0 0.0 6.7e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF48545.1 - 3e-08 33.9 0.1 7.3e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PXF48545.1 - 2.3e-06 27.6 0.0 4.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PXF48545.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 PXF48545.1 - 0.13 11.5 0.0 0.41 9.9 0.0 1.7 1 1 1 2 2 2 0 Septin Histone PF00125.24 PXF48546.1 - 1.8e-52 177.1 1.4 2e-52 177.0 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PXF48546.1 - 4.2e-05 24.2 0.5 4.8e-05 24.0 0.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 PXF48546.1 - 0.00045 20.3 0.1 0.00089 19.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PXF48546.1 - 0.00062 20.1 0.0 0.00094 19.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PXF48546.1 - 0.0025 18.1 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PXF48546.1 - 0.029 14.5 0.2 0.05 13.7 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Exo_endo_phos PF03372.23 PXF48547.1 - 1.2e-09 38.1 0.1 1.9e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family C2 PF00168.30 PXF48547.1 - 5.1e-06 26.7 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF179 PF02622.15 PXF48548.1 - 7.1e-16 58.6 0.0 7.6e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribophorin_II PF05817.14 PXF48549.1 - 2.8e-25 88.9 0.0 3.2e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2273 PF10031.9 PXF48549.1 - 0.14 12.2 1.5 0.42 10.7 1.5 1.8 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) TBCC PF07986.12 PXF48550.1 - 2.3e-21 75.7 1.5 3.9e-21 75.0 1.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 PXF48550.1 - 0.0028 17.3 1.2 0.0056 16.3 1.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEAD PF00270.29 PXF48551.1 - 7.7e-41 139.8 0.0 1.9e-40 138.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48551.1 - 8.4e-27 93.7 0.0 5.2e-25 87.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 PXF48551.1 - 0.0013 19.0 1.9 0.0046 17.2 1.4 2.4 1 1 0 1 1 1 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 PXF48551.1 - 0.0085 15.3 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 PXF48551.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 PXF48551.1 - 0.026 14.5 0.0 0.096 12.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1077 PF06417.12 PXF48552.1 - 5.9e-22 77.9 0.1 7.8e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) HEAT_2 PF13646.6 PXF48553.1 - 2.9e-13 50.0 6.7 2.8e-05 24.4 0.1 5.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 PXF48553.1 - 8.5e-10 38.0 14.5 0.37 11.2 0.1 7.3 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 PXF48553.1 - 3.7e-07 30.3 7.3 0.012 15.7 0.2 4.0 3 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PXF48553.1 - 2.1e-06 28.2 0.2 0.03 14.9 0.0 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 PXF48553.1 - 2.5e-06 27.9 3.9 0.23 12.0 0.0 4.4 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 PXF48553.1 - 0.0086 16.2 0.6 4 7.6 0.1 3.3 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 PXF48553.1 - 0.088 11.3 1.6 0.62 8.5 1.6 2.3 1 1 0 1 1 1 0 Adaptin N terminal region Spore_III_AB PF09548.10 PXF48553.1 - 0.67 10.0 3.4 3.7 7.6 0.3 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) HEAT_2 PF13646.6 PXF48554.1 - 2.4e-11 43.9 6.0 4.9e-05 23.6 0.5 5.4 4 1 1 5 5 5 5 HEAT repeats HEAT PF02985.22 PXF48554.1 - 1.6e-06 27.9 8.6 0.35 11.2 0.2 7.1 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 PXF48554.1 - 2.3e-05 24.5 1.4 0.15 12.1 0.0 4.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PXF48554.1 - 0.0022 16.6 1.0 0.42 9.1 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region DnaJ PF00226.31 PXF48557.1 - 3.7e-18 65.4 0.1 6.8e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4482 PF14818.6 PXF48557.1 - 0.0046 17.8 0.2 0.063 14.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4482) CorA PF01544.18 PXF48557.1 - 0.16 11.2 0.8 0.24 10.7 0.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ZapB PF06005.12 PXF48557.1 - 0.25 11.8 3.1 0.34 11.4 1.7 1.8 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 PXF48557.1 - 0.49 11.0 3.4 0.64 10.7 1.0 2.1 2 0 0 2 2 2 0 SlyX Rubis-subs-bind PF09273.11 PXF48558.1 - 9.2e-09 36.1 0.1 1.9e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PXF48558.1 - 1.8e-05 25.2 0.0 4.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 SET domain Asp PF00026.23 PXF48559.1 - 7.4e-38 130.7 0.0 1.8e-37 129.4 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 PXF48559.1 - 2.3e-10 40.5 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 PXF48559.1 - 0.0096 16.5 0.1 0.75 10.5 0.0 3.1 3 0 0 3 3 3 1 Aspartyl protease MFMR_assoc PF16596.5 PXF48559.1 - 0.057 13.9 12.0 0.12 12.8 12.0 1.5 1 0 0 1 1 1 0 Disordered region downstream of MFMR gag-asp_proteas PF13975.6 PXF48559.1 - 0.089 13.4 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease YihI PF04220.12 PXF48559.1 - 5.3 6.7 5.1 9.1 6.0 5.1 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) PTPA PF03095.15 PXF48560.1 - 1.1e-112 376.3 0.1 1.3e-112 376.2 0.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein N2227 PF07942.12 PXF48561.1 - 1.1e-56 192.1 0.0 1.5e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 PXF48561.1 - 0.088 13.6 0.0 0.31 11.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_3 PF13474.6 PXF48562.1 - 0.013 15.8 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain Lumazine_bd_2 PF12893.7 PXF48562.1 - 0.046 14.4 0.0 0.071 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding ClpS PF02617.17 PXF48563.1 - 1.1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ADSL_C PF10397.9 PXF48563.1 - 0.011 16.3 0.0 0.43 11.2 0.0 2.1 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Kunitz_BPTI PF00014.23 PXF48564.1 - 4.1e-10 39.7 6.6 5.4e-10 39.4 6.6 1.2 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-C4 PF00105.18 PXF48564.1 - 0.8 10.2 4.5 1.6 9.3 4.5 1.4 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF4516 PF14990.6 PXF48565.1 - 3.1e-07 30.0 0.1 4.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) E3_UFM1_ligase PF09743.9 PXF48566.1 - 1.2e-79 267.7 0.1 1.8e-79 267.2 0.1 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 DUF4630 PF15443.6 PXF48566.1 - 0.016 15.4 0.1 0.045 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) DnaJ_CXXCXGXG PF00684.19 PXF48567.1 - 0.013 15.8 10.5 0.47 10.8 10.4 2.8 1 1 1 2 2 2 0 DnaJ central domain ATP11 PF06644.11 PXF48568.1 - 5.5e-15 55.9 0.2 6e-15 55.8 0.2 1.0 1 0 0 1 1 1 1 ATP11 protein SLIDE PF09111.10 PXF48568.1 - 0.046 13.7 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 SLIDE AATF-Che1 PF13339.6 PXF48569.1 - 0.029 15.0 1.7 0.069 13.8 1.7 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Sulfotransfer_3 PF13469.6 PXF48570.1 - 0.022 15.1 0.5 3 8.2 0.1 2.7 1 1 1 2 2 2 0 Sulfotransferase family TMEM208_SND2 PF05620.11 PXF48571.1 - 2e-34 118.8 0.1 2.2e-34 118.7 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF1700 PF08006.11 PXF48571.1 - 6.6 6.2 7.0 7.5 6.1 5.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) Exo_endo_phos PF03372.23 PXF48573.1 - 1.6e-08 34.4 0.0 2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PXF48573.1 - 0.042 13.7 0.3 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase BRCT_2 PF16589.5 PXF48574.1 - 5.9e-07 29.8 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PXF48574.1 - 7.8e-06 26.1 0.0 3.3e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT PF00533.26 PXF48574.1 - 7.9e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PXF48574.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain QueC PF06508.13 PXF48575.1 - 9.1e-67 224.6 0.0 1.1e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 PXF48575.1 - 2.8e-06 27.2 0.1 3.9e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 PXF48575.1 - 0.0064 15.6 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD synthase PAPS_reduct PF01507.19 PXF48575.1 - 0.012 15.7 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family AP_endonuc_2 PF01261.24 PXF48575.1 - 0.016 14.6 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ThiI PF02568.14 PXF48575.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 PXF48575.1 - 0.21 10.4 0.1 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Methyltransf_21 PF05050.12 PXF48576.1 - 9.5e-17 61.6 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 PXF48576.1 - 0.0032 17.3 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RNase_H2_suC PF08615.11 PXF48579.1 - 1.1e-05 25.6 0.0 0.011 15.9 0.0 3.2 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_2 PF07719.17 PXF48580.1 - 1e-31 106.4 18.2 5.9e-05 22.9 0.1 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 PXF48580.1 - 1.9e-29 100.3 11.3 0.00017 21.3 0.0 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 PXF48580.1 - 3.1e-26 91.7 16.2 7.9e-06 26.4 0.1 7.9 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 PXF48580.1 - 1.7e-24 83.9 6.9 0.00062 19.8 0.0 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 PXF48580.1 - 4.6e-22 78.3 17.7 3.8e-05 24.1 0.2 8.3 7 3 2 9 9 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 PXF48580.1 - 8.9e-22 75.9 14.4 0.0042 17.8 0.1 9.5 5 2 4 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 PXF48580.1 - 2.6e-21 75.7 12.7 0.00097 19.4 0.1 7.7 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 PXF48580.1 - 1.5e-19 69.4 8.5 2.1e-05 24.1 0.8 8.5 6 2 3 9 9 9 4 TPR repeat ANAPC3 PF12895.7 PXF48580.1 - 4.8e-18 65.2 6.2 2.1e-09 37.4 0.0 5.6 5 2 3 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PXF48580.1 - 3e-15 55.0 6.5 0.0057 16.6 0.0 7.0 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 PXF48580.1 - 4e-14 51.9 5.2 0.44 11.1 0.0 9.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 PXF48580.1 - 8.3e-11 41.4 3.8 0.85 10.4 0.1 6.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PXF48580.1 - 6.3e-10 39.1 8.7 0.28 11.4 0.2 5.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 PXF48580.1 - 2.3e-08 34.1 9.9 0.18 12.5 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 PXF48580.1 - 3.4e-07 29.8 7.5 0.061 12.5 0.1 5.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 PXF48580.1 - 5.6e-07 29.2 15.5 0.13 12.2 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF48580.1 - 0.001 18.5 6.0 0.32 10.3 0.1 4.7 4 1 0 5 5 5 1 MalT-like TPR region Fis1_TPR_C PF14853.6 PXF48580.1 - 0.0028 17.7 0.1 2.8 8.1 0.1 3.1 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 PXF48580.1 - 0.022 15.1 4.8 5.2 7.5 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PXF48580.1 - 0.078 12.6 0.7 3.3 7.4 0.1 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 PXF48580.1 - 1.5 9.3 6.1 5.7 7.4 0.4 4.1 4 1 0 4 4 3 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 PXF48580.1 - 9.3 5.8 7.6 5.8 6.5 0.1 4.2 6 0 0 6 6 6 0 SHNi-TPR WW PF00397.26 PXF48581.1 - 3.3e-37 126.2 37.4 5.9e-12 45.5 2.1 4.8 4 0 0 4 4 4 4 WW domain FF PF01846.19 PXF48581.1 - 3.9e-10 39.7 9.9 3e-06 27.3 0.0 5.6 5 0 0 5 5 5 2 FF domain Glyco_hyd_101C PF17451.2 PXF48581.1 - 0.061 13.6 15.2 0.78 10.0 0.6 4.7 3 1 0 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain Syncollin PF15138.6 PXF48581.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Syncollin Holin_BhlA PF10960.8 PXF48581.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.9 2 0 0 2 2 2 0 BhlA holin family Cupin_2 PF07883.11 PXF48582.1 - 0.00012 21.8 0.0 0.00034 20.3 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Ribosomal_S25 PF03297.15 PXF48583.1 - 4.6e-39 132.7 6.0 5.5e-39 132.4 6.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein PCI PF01399.27 PXF48583.1 - 0.002 18.6 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 PCI domain MarR_2 PF12802.7 PXF48583.1 - 0.062 13.2 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 MarR family MamL-1 PF09596.10 PXF48585.1 - 0.069 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 MamL-1 domain Spc42p PF11544.8 PXF48585.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p ASXH PF13919.6 PXF48586.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Asx homology domain MIR PF02815.19 PXF48587.1 - 5.2e-18 65.5 4.6 8.1e-15 55.1 1.5 3.0 1 1 1 2 2 2 2 MIR domain RRXRR PF14239.6 PXF48587.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 RRXRR protein CAAD PF14159.6 PXF48588.1 - 6.3e-15 54.8 0.2 9.4e-15 54.2 0.2 1.2 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LysE PF01810.18 PXF48588.1 - 0.12 11.8 1.9 0.19 11.2 1.9 1.2 1 0 0 1 1 1 0 LysE type translocator Presenilin PF01080.17 PXF48588.1 - 0.3 9.8 1.7 0.39 9.4 1.7 1.1 1 0 0 1 1 1 0 Presenilin ADH_N PF08240.12 PXF48590.1 - 1.8e-25 88.9 3.6 4.3e-25 87.7 3.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF48590.1 - 1.2e-24 86.7 0.1 2e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PXF48590.1 - 2.3e-06 27.2 0.2 1.5e-05 24.6 0.1 2.1 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PXF48590.1 - 4e-06 27.9 0.0 6.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CLLAC PF15675.5 PXF48590.1 - 0.036 13.6 5.0 0.071 12.7 5.0 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain AlaDh_PNT_C PF01262.21 PXF48590.1 - 0.049 12.9 1.0 0.082 12.2 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MinC_C PF03775.16 PXF48590.1 - 0.16 12.0 0.9 1.7 8.7 1.2 2.1 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Met_10 PF02475.16 PXF48590.1 - 0.19 11.5 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Met-10+ like-protein 2-Hacid_dh_C PF02826.19 PXF48590.1 - 0.2 11.0 0.2 0.33 10.3 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIF_beta PF02270.15 PXF48591.1 - 5.6e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 PXF48591.1 - 5.5e-05 23.9 0.8 5.5e-05 23.9 0.8 2.6 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus DLIC PF05783.11 PXF48591.1 - 0.011 14.6 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) EAP30 PF04157.16 PXF48592.1 - 0.017 14.5 0.0 0.042 13.1 0.0 1.8 1 0 0 1 1 1 0 EAP30/Vps36 family OST3_OST6 PF04756.13 PXF48592.1 - 0.038 13.3 0.8 0.076 12.4 0.8 1.6 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TFIIA_gamma_N PF02268.16 PXF48593.1 - 5.4e-13 48.7 0.1 9.6e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 PXF48593.1 - 2e-07 31.0 0.1 3.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF393 PF04134.12 PXF48594.1 - 5.4e-21 76.0 0.0 6.2e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 FAD_binding_1 PF00667.20 PXF48595.1 - 2.9e-43 148.0 0.0 4.8e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PXF48595.1 - 7.3e-25 87.8 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PXF48595.1 - 2.5e-13 50.6 0.0 4.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHFR_2 PF06442.11 PXF48595.1 - 0.04 13.7 0.1 67 3.4 0.0 3.3 3 0 0 3 3 3 0 R67 dihydrofolate reductase FKBP_C PF00254.28 PXF48596.1 - 2.2e-20 72.7 0.0 3.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glycos_transf_2 PF00535.26 PXF48597.1 - 1.4e-26 93.3 0.0 3.3e-26 92.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF48597.1 - 9e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF48597.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF48598.1 - 4.9e-21 75.3 0.0 9.5e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 PXF48598.1 - 5.2e-09 35.6 0.2 1.3e-08 34.3 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 PXF48598.1 - 6.8e-06 26.1 0.0 2.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF48598.1 - 0.00016 21.3 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Prefoldin_2 PF01920.20 PXF48600.1 - 4.4e-20 71.6 3.5 5e-20 71.4 3.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit V_ATPase_I PF01496.19 PXF48600.1 - 0.0038 15.2 0.8 0.0045 15.0 0.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Not3 PF04065.15 PXF48600.1 - 0.011 15.2 0.6 0.011 15.2 0.6 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component PP1_inhibitor PF05361.12 PXF48600.1 - 0.021 14.8 2.6 0.034 14.1 2.6 1.3 1 1 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor MetOD2 PF18548.1 PXF48600.1 - 0.048 13.8 1.9 0.4 10.8 0.2 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 DUF1664 PF07889.12 PXF48600.1 - 0.059 13.4 0.3 0.059 13.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 PXF48600.1 - 0.15 12.6 4.9 0.36 11.4 4.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region AD PF09793.9 PXF48600.1 - 0.22 11.7 0.3 0.22 11.7 0.3 1.8 2 0 0 2 2 2 0 Anticodon-binding domain Prefoldin PF02996.17 PXF48600.1 - 0.26 11.2 4.3 1.3 8.9 4.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF829 PF05705.14 PXF48601.1 - 4.9e-33 115.0 0.0 1.4e-32 113.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF5363 PF17320.2 PXF48601.1 - 0.019 14.8 0.5 0.019 14.8 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5363) Sel1 PF08238.12 PXF48603.1 - 6.3e-95 309.5 55.7 3.9e-06 27.4 2.0 17.5 17 0 0 17 17 17 17 Sel1 repeat Pkinase PF00069.25 PXF48603.1 - 2.8e-14 53.1 0.0 4.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48603.1 - 2e-13 50.2 0.0 3.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.6 PXF48603.1 - 4.6e-11 41.9 16.6 0.0019 18.1 0.2 9.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF48603.1 - 6.3e-08 32.8 31.0 0.65 10.8 0.0 13.4 14 1 1 15 15 14 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF48603.1 - 3.4e-05 24.2 16.4 1.3 9.6 0.3 8.9 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF48603.1 - 0.0017 19.0 23.9 0.75 10.5 0.1 8.6 7 2 3 10 10 10 3 Tetratricopeptide repeat RNA_pol_N PF01194.17 PXF48603.1 - 0.04 14.2 0.1 22 5.5 0.0 4.2 3 1 0 3 3 3 0 RNA polymerases N / 8 kDa subunit TPR_1 PF00515.28 PXF48603.1 - 0.053 13.4 0.0 0.053 13.4 0.0 13.0 16 2 0 16 16 15 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF48603.1 - 0.33 11.3 20.5 9.3 6.6 0.1 7.9 8 3 0 8 8 8 0 Tetratricopeptide repeat ComR_TPR PF18710.1 PXF48603.1 - 1.7 8.1 3.1 6.5 6.2 0.0 3.3 4 1 1 5 5 5 0 ComR tetratricopeptide MIT PF04212.18 PXF48603.1 - 2 8.5 28.9 21 5.3 0.0 9.3 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain DUF4778 PF16008.5 PXF48603.1 - 3.5 7.6 6.5 2.6 8.0 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) RNA_pol_N PF01194.17 PXF48604.1 - 5.6e-31 106.6 2.1 6.3e-31 106.5 2.1 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 PXF48604.1 - 0.0096 16.2 0.5 0.015 15.5 0.5 1.4 1 1 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_S7e PF01251.18 PXF48605.1 - 8.4e-84 279.9 3.1 9.5e-84 279.7 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e NOG1 PF06858.14 PXF48605.1 - 0.061 13.1 0.2 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) NAD_binding_10 PF13460.6 PXF48606.1 - 4.9e-05 23.3 0.0 5.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PXF48606.1 - 0.00017 20.7 0.0 0.0002 20.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PXF48606.1 - 0.0046 16.4 0.0 0.013 15.0 0.0 1.5 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 PXF48606.1 - 0.063 13.5 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain HopA1 PF17914.1 PXF48606.1 - 0.066 13.0 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 HopA1 effector protein family HEPN_RnaseLS PF18869.1 PXF48606.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RnaseLS-like HEPN adh_short PF00106.25 PXF48606.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.3 1 1 0 1 1 1 0 short chain dehydrogenase PWWP PF00855.17 PXF48609.1 - 1.4e-07 31.8 0.2 4.6e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Polyketide_cyc2 PF10604.9 PXF48610.1 - 2.1e-07 31.3 0.0 3.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PXF48610.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.21 PXF48611.1 - 0.0021 17.6 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PXF48611.1 - 0.14 12.0 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding CRAL_TRIO PF00650.20 PXF48612.1 - 3.8e-22 78.7 0.0 5.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PXF48612.1 - 3.2e-07 30.6 0.0 5.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DDE_1 PF03184.19 PXF48613.1 - 4.4e-19 68.8 0.2 9e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 PXF48613.1 - 5.7e-11 41.9 0.5 4.4e-08 32.6 0.7 2.6 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 PXF48613.1 - 6.3e-05 22.7 1.8 0.0033 17.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 PXF48613.1 - 0.00029 20.9 1.7 0.0049 17.0 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 PXF48613.1 - 0.00094 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_38 PF13936.6 PXF48613.1 - 0.0019 18.0 0.3 0.0047 16.7 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 PXF48613.1 - 0.06 13.4 0.3 0.37 10.9 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 PXF48613.1 - 5.3 7.4 9.3 0.19 12.1 1.5 2.6 3 0 0 3 3 3 0 Transposase NPCC PF08058.11 PXF48614.1 - 0.0051 16.9 0.8 0.1 12.7 0.8 2.3 1 1 0 1 1 1 1 Nuclear pore complex component Jagunal PF07086.12 PXF48614.1 - 0.077 13.1 3.2 0.37 10.8 0.1 2.7 2 1 1 3 3 3 0 Jagunal, ER re-organisation during oogenesis PMT_2 PF13231.6 PXF48614.1 - 0.24 11.6 4.8 0.2 11.9 0.6 2.5 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4519 PF15012.6 PXF48614.1 - 9.8 6.4 12.5 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) SRF-TF PF00319.18 PXF48615.1 - 1.5e-20 72.4 0.0 2.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF456 PF04306.13 PXF48616.1 - 3.4e-05 24.1 1.4 4.5e-05 23.7 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) OPT PF03169.15 PXF48616.1 - 0.0014 17.4 0.2 0.02 13.6 0.3 1.9 1 1 1 2 2 2 2 OPT oligopeptide transporter protein zf-LITAF-like PF10601.9 PXF48616.1 - 0.064 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Solute_trans_a PF03619.16 PXF48616.1 - 0.066 12.7 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter Ostalpha DUF5305 PF17231.2 PXF48616.1 - 0.2 11.0 0.2 3 7.2 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5305) LRR19-TM PF15176.6 PXF48616.1 - 3.5 7.7 5.7 0.44 10.6 0.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2272 PF10030.9 PXF48617.1 - 1.8e-24 86.6 0.2 2.9e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) CHAP PF05257.16 PXF48617.1 - 0.0048 17.4 3.8 0.13 12.9 3.8 2.4 1 1 0 1 1 1 1 CHAP domain DDRGK PF09756.9 PXF48618.1 - 0.0054 16.3 15.2 0.0065 16.1 15.2 1.0 1 0 0 1 1 1 1 DDRGK domain EIAV_GP90 PF00971.18 PXF48618.1 - 0.16 10.6 0.7 0.23 10.1 0.7 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 Di19_C PF14571.6 PXF48618.1 - 0.79 10.3 4.9 1.1 9.8 4.9 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Connexin PF00029.19 PXF48618.1 - 1.4 8.6 3.0 1.6 8.4 3.0 1.0 1 0 0 1 1 1 0 Connexin UPF0016 PF01169.19 PXF48619.1 - 2.5e-35 120.6 34.4 1.6e-20 73.2 9.4 3.7 4 0 0 4 4 4 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 PXF48619.1 - 2.4 7.9 11.8 14 5.4 11.8 2.1 1 1 0 1 1 1 0 Putative manganese efflux pump TerC PF03741.16 PXF48619.1 - 2.8 7.6 16.5 0.076 12.7 6.7 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family WD40 PF00400.32 PXF48620.1 - 0.072 14.0 0.0 0.27 12.2 0.0 1.9 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.32 PXF48621.1 - 8.2e-06 26.5 0.2 2.9e-05 24.7 0.2 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Iso_dh PF00180.20 PXF48622.1 - 1e-128 429.4 0.0 1.2e-128 429.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2934 PF11154.8 PXF48622.1 - 0.018 14.7 0.5 0.033 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) zf-C3HC4 PF00097.25 PXF48623.1 - 0.0035 17.2 7.8 0.0035 17.2 7.8 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PXF48623.1 - 7.5 6.5 38.0 0.077 12.9 2.1 4.5 4 0 0 4 4 4 0 PHD-finger DUF647 PF04884.14 PXF48624.1 - 9.9e-50 169.4 0.0 1.5e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4033 PF13225.6 PXF48626.1 - 4.3e-28 97.1 0.8 1.3e-27 95.6 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4033) DUF4328 PF14219.6 PXF48627.1 - 0.015 14.9 0.5 0.024 14.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PTPS_related PF10131.9 PXF48627.1 - 0.12 10.6 1.2 0.17 10.2 1.2 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF4234 PF14018.6 PXF48627.1 - 0.13 12.4 1.4 0.24 11.6 0.5 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) Mito_carr PF00153.27 PXF48628.1 - 3.4e-64 212.8 4.2 1e-23 83.1 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PI3_PI4_kinase PF00454.27 PXF48629.1 - 1.3e-23 84.1 0.0 7.2e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase MatE PF01554.18 PXF48630.1 - 4e-44 150.1 33.3 5.9e-31 107.3 10.9 2.4 2 0 0 2 2 2 2 MatE S6PP PF05116.13 PXF48631.1 - 1.2e-13 51.1 0.0 1.5e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Guanylate_kin PF00625.21 PXF48632.1 - 5.8e-57 192.3 0.0 6.6e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 PXF48632.1 - 7.8e-06 26.5 0.0 1.7e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF48632.1 - 3.7e-05 24.2 0.2 7.8e-05 23.1 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF48632.1 - 0.00016 21.7 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase PTS_IIB PF02302.17 PXF48632.1 - 0.0026 18.4 0.4 13 6.6 0.0 3.2 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Zeta_toxin PF06414.12 PXF48632.1 - 0.015 14.5 0.3 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 PXF48632.1 - 0.017 15.3 0.1 0.22 11.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PXF48632.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA_22 PF13401.6 PXF48632.1 - 0.022 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PXF48632.1 - 0.058 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PXF48632.1 - 0.058 13.8 1.6 0.075 13.5 0.1 2.1 2 2 1 3 3 3 0 AAA domain AAA_30 PF13604.6 PXF48632.1 - 0.061 13.0 0.1 0.18 11.5 0.0 1.6 1 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PXF48632.1 - 0.098 12.7 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 PXF48632.1 - 0.11 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PXF48632.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF4588 PF15251.6 PXF48633.1 - 1.9e-06 27.9 3.1 3.3e-06 27.1 3.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) HEAT_2 PF13646.6 PXF48634.1 - 1.5e-12 47.7 1.8 0.0015 18.9 0.1 4.9 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.22 PXF48634.1 - 4e-08 32.8 13.5 0.016 15.4 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 PXF48634.1 - 1.8e-06 28.1 3.3 0.0052 16.8 0.5 4.0 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PXF48634.1 - 0.0012 19.3 0.8 3.7 8.2 0.1 4.2 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PXF48634.1 - 0.0039 15.8 4.2 1 7.8 1.6 3.3 2 1 1 3 3 3 2 Adaptin N terminal region YhdB PF14148.6 PXF48634.1 - 0.059 13.5 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 0 YhdB-like protein RTP1_C1 PF10363.9 PXF48634.1 - 0.12 12.6 0.4 8.8 6.5 0.0 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 SGS PF05002.15 PXF48635.1 - 6.5e-22 77.4 1.9 6.5e-22 77.4 1.9 2.2 2 0 0 2 2 2 1 SGS domain CS PF04969.16 PXF48635.1 - 1.3e-14 55.0 0.7 2.8e-14 53.9 0.7 1.6 1 0 0 1 1 1 1 CS domain TPR_8 PF13181.6 PXF48635.1 - 9.5e-07 28.6 6.4 0.045 14.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF48635.1 - 5.1e-06 27.0 2.7 1.8e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF48635.1 - 6.8e-06 25.7 0.6 0.00049 19.8 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF48635.1 - 7.4e-06 26.1 1.5 2.6e-05 24.4 1.4 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 PXF48635.1 - 9.5e-06 25.4 7.0 0.0014 18.6 1.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF48635.1 - 0.00012 22.2 0.3 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF48635.1 - 0.00024 21.5 2.3 0.0017 18.8 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF48635.1 - 0.011 16.1 3.8 0.02 15.2 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PXF48635.1 - 0.092 13.6 4.7 2.6 9.1 0.0 3.8 3 1 2 5 5 3 0 Tetratricopeptide repeat TCRP1 PF14944.6 PXF48635.1 - 0.097 12.6 0.1 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 REPA_OB_2 PF16900.5 PXF48635.1 - 0.12 12.3 0.5 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 Replication protein A OB domain TPR_MalT PF17874.1 PXF48635.1 - 0.16 11.3 2.3 0.46 9.8 0.2 2.0 2 0 0 2 2 2 0 MalT-like TPR region MIT PF04212.18 PXF48635.1 - 0.31 11.2 4.2 1.9 8.6 1.4 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Acyltransferase PF01553.21 PXF48636.1 - 7.8e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase BSD PF03909.17 PXF48637.1 - 1.8e-10 40.6 0.1 9.6e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 BSD domain Baculo_PEP_C PF04513.12 PXF48637.1 - 0.0098 15.9 0.2 0.19 11.8 0.7 2.4 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus T2SSJ PF11612.8 PXF48637.1 - 0.024 14.8 0.5 0.059 13.6 0.5 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J HEAT_2 PF13646.6 PXF48638.1 - 3.8e-14 52.8 17.7 4.1e-06 27.1 3.3 6.0 6 1 0 6 6 6 4 HEAT repeats Cnd1 PF12717.7 PXF48638.1 - 4.8e-10 39.7 0.6 0.0003 20.9 0.1 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PXF48638.1 - 2.6e-08 33.4 24.7 0.056 13.7 0.1 8.7 10 0 0 10 10 10 3 HEAT repeat Adaptin_N PF01602.20 PXF48638.1 - 7.1e-07 28.2 1.1 0.077 11.5 1.1 3.5 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 PXF48638.1 - 9.3e-05 22.8 14.0 0.094 13.3 0.6 6.4 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.7 PXF48638.1 - 0.0058 16.9 0.4 2.2 8.7 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_C PF11698.8 PXF48638.1 - 0.026 14.7 0.3 31 4.7 0.0 3.5 3 0 0 3 3 3 0 V-ATPase subunit H CLASP_N PF12348.8 PXF48638.1 - 0.03 13.9 0.4 4.8 6.7 0.0 3.6 4 1 0 4 4 4 0 CLASP N terminal BAG PF02179.16 PXF48639.1 - 3.4e-11 43.4 1.4 6.6e-11 42.5 1.4 1.5 1 0 0 1 1 1 1 BAG domain WW PF00397.26 PXF48639.1 - 0.029 14.5 2.6 1.3 9.1 0.0 3.5 2 1 1 3 3 3 0 WW domain Guanylate_cyc_2 PF09778.9 PXF48641.1 - 2e-30 105.8 0.1 2.5e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39 PF03412.15 PXF48641.1 - 4.6e-05 23.2 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C39_2 PF13529.6 PXF48641.1 - 0.0038 17.8 0.0 0.0041 17.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family DUF3335 PF11814.8 PXF48641.1 - 0.022 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family RRM_1 PF00076.22 PXF48642.1 - 1.4e-20 72.8 0.3 5.9e-11 42.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF48642.1 - 2.5e-07 30.7 0.0 0.00056 20.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Fer4_NifH PF00142.18 PXF48642.1 - 0.13 11.7 0.2 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Shugoshin_N PF07558.11 PXF48644.1 - 1.4e-05 24.8 0.4 1.4e-05 24.8 0.4 2.7 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Mod_r PF07200.13 PXF48644.1 - 0.0049 17.0 2.6 0.011 15.9 2.6 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HLH PF00010.26 PXF48644.1 - 0.005 16.8 1.6 0.005 16.8 1.6 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FAP PF07174.11 PXF48644.1 - 0.022 14.3 6.0 0.036 13.5 6.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) APG6_N PF17675.1 PXF48644.1 - 0.023 15.2 4.3 0.054 14.0 4.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2968 PF11180.8 PXF48644.1 - 0.026 14.2 2.9 0.05 13.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ZapB PF06005.12 PXF48644.1 - 0.046 14.2 3.1 0.21 12.0 3.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 PXF48644.1 - 0.053 14.2 2.8 0.057 14.1 1.2 1.9 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 PXF48644.1 - 0.13 11.6 1.3 0.2 11.0 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 PXF48644.1 - 0.21 11.4 1.7 0.79 9.5 1.6 2.1 1 1 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 PXF48644.1 - 0.29 11.6 4.3 0.76 10.2 4.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 PXF48644.1 - 0.46 10.5 7.9 0.035 14.1 2.6 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 PXF48644.1 - 0.46 9.8 6.3 0.81 9.0 6.3 1.4 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 PXF48644.1 - 0.52 10.7 5.6 0.17 12.3 2.5 1.8 2 0 0 2 2 2 0 Fez1 CASP_C PF08172.12 PXF48644.1 - 0.58 9.4 7.9 1.9 7.8 0.3 2.8 2 1 1 3 3 3 0 CASP C terminal AOX PF01786.17 PXF48645.1 - 1.2e-76 257.1 1.7 1.6e-76 256.7 1.7 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 PXF48645.1 - 0.00036 20.3 0.3 0.00076 19.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 SAE2 PF08573.10 PXF48645.1 - 0.089 13.9 0.1 0.21 12.7 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus AAA_assoc PF14363.6 PXF48648.1 - 0.027 14.8 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DIPSY PF11763.8 PXF48648.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Ribosomal_S14 PF00253.21 PXF48649.1 - 0.043 13.6 1.4 0.071 12.9 1.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e CAP_N PF01213.19 PXF48651.1 - 1.8e-35 123.0 0.0 5.1e-18 65.6 0.0 2.2 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal Chloroa_b-bind PF00504.21 PXF48652.1 - 3e-33 115.6 0.0 4.9e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Med14 PF08638.11 PXF48653.1 - 5.4e-13 48.8 0.0 1.6e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit MED14 HpaP PF09483.10 PXF48653.1 - 0.0088 16.3 0.0 0.087 13.1 0.0 2.6 2 0 0 2 2 2 1 Type III secretion protein (HpaP) Lactamase_B_2 PF12706.7 PXF48654.1 - 5.5e-09 35.8 0.9 2e-08 34.0 0.9 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain S1 PF00575.23 PXF48655.1 - 4.2e-11 43.0 6.8 4.2e-08 33.4 0.3 3.5 3 0 0 3 3 3 2 S1 RNA binding domain Fringe PF02434.16 PXF48656.1 - 4.4e-05 23.0 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 PXF48656.1 - 0.01 15.6 0.1 0.064 13.1 0.2 2.2 2 1 0 2 2 2 0 Galactosyltransferase adh_short PF00106.25 PXF48657.1 - 8.7e-35 120.0 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF48657.1 - 7.2e-21 74.8 0.0 1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF48657.1 - 4.5e-06 26.7 0.1 6.2e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PXF48657.1 - 0.005 16.2 0.0 0.0075 15.7 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_transf_4 PF13439.6 PXF48657.1 - 0.027 14.5 0.0 5.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_tran_WecB PF03808.13 PXF48657.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.21 PXF48657.1 - 0.19 11.2 0.4 0.54 9.7 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mur_ligase_M PF08245.12 PXF48658.1 - 2.7e-09 37.3 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 PXF48658.1 - 8.9e-05 22.7 0.0 0.00046 20.4 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain SMBP PF16785.5 PXF48658.1 - 0.047 13.9 1.6 0.089 13.0 1.6 1.4 1 0 0 1 1 1 0 Small metal-binding protein Sigma70_r2 PF04542.14 PXF48659.1 - 8.6e-17 60.7 0.1 2.2e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 PXF48659.1 - 4.9e-15 55.4 1.2 1.4e-06 28.3 0.0 3.1 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r4 PF04545.16 PXF48659.1 - 1.8e-14 53.0 0.9 8.7e-14 50.8 0.3 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 PXF48659.1 - 0.02 14.7 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 HTH DNA binding domain TFIIA PF03153.13 PXF48659.1 - 0.023 14.7 25.4 0.033 14.2 25.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 PXF48659.1 - 0.028 14.8 5.7 0.043 14.2 5.7 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like HTH_28 PF13518.6 PXF48659.1 - 0.066 13.3 5.7 20 5.4 0.0 4.4 4 0 0 4 4 4 0 Helix-turn-helix domain MerR PF00376.23 PXF48659.1 - 0.069 12.9 0.1 1.9 8.3 0.0 3.1 3 0 0 3 3 3 0 MerR family regulatory protein Sigma70_r1_2 PF00140.20 PXF48659.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-70 factor, region 1.2 Sin_N PF04801.13 PXF48659.1 - 0.21 10.8 18.2 0.27 10.4 18.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4638 PF15472.6 PXF48659.1 - 0.26 11.0 12.5 0.44 10.2 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Presenilin PF01080.17 PXF48659.1 - 0.47 9.2 12.1 0.59 8.8 12.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 PXF48659.1 - 0.5 10.6 14.1 1.1 9.5 14.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Ndc1_Nup PF09531.10 PXF48659.1 - 1.9 7.0 14.3 2.5 6.7 14.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3292 PF11696.8 PXF48659.1 - 2.1 6.6 13.6 3.1 6.0 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Zip PF02535.22 PXF48659.1 - 4.6 6.4 6.0 5.8 6.0 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 PXF48659.1 - 5.3 7.0 10.1 8.9 6.3 10.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 PXF48659.1 - 7.8 5.2 10.7 11 4.7 10.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter HLH PF00010.26 PXF48660.1 - 9e-10 38.4 0.8 9e-10 38.4 0.8 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hint PF01079.20 PXF48661.1 - 1.2e-30 106.7 0.2 1.8e-30 106.1 0.2 1.2 1 0 0 1 1 1 1 Hint module CENP-B_dimeris PF09026.10 PXF48661.1 - 0.0008 19.8 1.7 0.0018 18.7 1.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Hint_2 PF13403.6 PXF48661.1 - 0.0065 16.8 0.0 0.089 13.1 0.0 2.2 1 1 1 2 2 2 1 Hint domain Hom_end_hint PF05203.16 PXF48661.1 - 0.048 13.6 0.0 9.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Hom_end-associated Hint Vint PF14623.6 PXF48661.1 - 0.076 12.8 0.0 0.72 9.7 0.0 2.4 2 1 1 3 3 3 0 Hint-domain Cuticle_3 PF11018.8 PXF48661.1 - 0.23 11.7 16.1 4.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Pupal cuticle protein C1 Rib_recp_KP_reg PF05104.12 PXF48661.1 - 0.65 11.0 13.6 0.96 10.5 13.6 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region SPX PF03105.19 PXF48661.1 - 1.1 9.1 4.2 1.3 8.8 4.2 1.1 1 0 0 1 1 1 0 SPX domain Cwf_Cwc_15 PF04889.12 PXF48661.1 - 1.1 8.9 3.0 1.7 8.3 3.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Retinal PF15449.6 PXF48661.1 - 1.8 6.2 17.1 2.3 5.9 17.1 1.0 1 0 0 1 1 1 0 Retinal protein CCDC53 PF10152.9 PXF48661.1 - 5.2 7.5 6.0 8.6 6.8 6.0 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex HisG PF01634.18 PXF48662.1 - 2.5e-40 138.0 0.0 3.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 PXF48662.1 - 1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain AAA PF00004.29 PXF48663.1 - 2.9e-29 102.2 0.0 4.3e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PXF48663.1 - 1.1e-09 39.0 5.7 0.00027 21.4 0.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 PXF48663.1 - 3.8e-08 33.0 1.1 1.5e-06 27.9 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 PXF48663.1 - 3e-07 30.8 0.4 0.048 13.9 0.1 4.4 3 2 2 5 5 4 1 AAA domain Zeta_toxin PF06414.12 PXF48663.1 - 4.8e-07 29.3 0.1 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 PXF48663.1 - 6.7e-06 25.4 0.0 0.00029 20.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PXF48663.1 - 4.6e-05 23.5 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PXF48663.1 - 4.7e-05 23.0 0.1 0.54 10.0 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 PXF48663.1 - 4.9e-05 23.3 0.0 0.00078 19.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PXF48663.1 - 5.5e-05 22.5 0.3 0.063 12.5 0.1 3.0 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_18 PF13238.6 PXF48663.1 - 0.00011 22.8 0.0 0.03 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF48663.1 - 0.00011 22.0 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PXF48663.1 - 0.00061 19.3 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region CPT PF07931.12 PXF48663.1 - 0.0027 17.6 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 PXF48663.1 - 0.0035 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 PXF48663.1 - 0.0037 17.4 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF48663.1 - 0.0062 16.3 0.4 0.015 15.0 0.4 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 PXF48663.1 - 0.0078 15.9 0.1 3.4 7.3 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 PXF48663.1 - 0.0088 16.0 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PXF48663.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PXF48663.1 - 0.013 15.9 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 PXF48663.1 - 0.016 14.8 1.9 0.68 9.5 0.2 2.9 3 1 1 4 4 3 0 AAA domain Zot PF05707.12 PXF48663.1 - 0.021 14.5 0.0 11 5.6 0.0 3.4 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 PXF48663.1 - 0.026 13.8 0.1 0.074 12.3 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 PXF48663.1 - 0.026 14.4 1.9 1.7 8.5 0.3 3.9 3 1 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 PXF48663.1 - 0.031 14.6 0.0 0.089 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.6 PXF48663.1 - 0.037 13.9 0.0 9 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MCM PF00493.23 PXF48663.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain RuvB_N PF05496.12 PXF48663.1 - 0.073 12.8 0.2 0.23 11.2 0.1 2.0 2 1 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 PXF48663.1 - 0.12 12.9 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.9 PXF48663.1 - 0.12 11.5 0.1 10 5.1 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 PXF48663.1 - 0.13 11.6 0.0 5.5 6.3 0.0 2.7 2 1 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 PXF48663.1 - 0.18 11.7 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Q_salvage PF10343.9 PXF48664.1 - 1.4e-103 346.4 0.7 1.8e-102 342.7 0.7 2.0 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Qua1 PF16274.5 PXF48664.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Qua1 domain HTH_Tnp_Tc5 PF03221.16 PXF48664.1 - 0.12 12.4 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Sec23_trunk PF04811.15 PXF48666.1 - 4.5e-36 124.6 0.0 6.9e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PXF48666.1 - 6.2e-18 64.5 0.3 1.2e-17 63.6 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PXF48666.1 - 1e-11 44.7 1.0 1.9e-11 43.8 1.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PXF48666.1 - 5.2e-09 36.7 0.0 1.1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sde2_N_Ubi PF13019.6 PXF48667.1 - 1.2e-16 60.9 1.0 1.8e-16 60.4 1.0 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Glyoxalase PF00903.25 PXF48668.1 - 9.7e-14 51.7 0.0 6.8e-06 26.3 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PXF48668.1 - 2.2e-10 40.8 0.6 2.6e-05 24.4 0.1 3.1 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PXF48668.1 - 0.00012 22.8 0.3 0.054 14.3 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 PXF48668.1 - 0.096 12.8 0.0 4.8 7.3 0.0 2.8 3 1 0 3 3 3 0 Glyoxalase-like domain Phage_TAC_9 PF10876.8 PXF48669.1 - 0.087 12.9 0.0 0.093 12.8 0.0 1.0 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC RIO1 PF01163.22 PXF48670.1 - 1.4e-61 207.4 0.0 2.7e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family AAA_18 PF13238.6 PXF48671.1 - 9.1e-27 94.2 0.1 3.3e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 PXF48671.1 - 3.4e-06 27.1 0.4 0.0066 16.3 0.7 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 PXF48671.1 - 7.3e-06 26.4 0.1 4.7e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 PXF48671.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 PXF48671.1 - 0.00075 19.7 0.4 0.011 15.9 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PXF48671.1 - 0.00096 19.4 2.0 0.012 15.9 2.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF48671.1 - 0.0013 19.2 0.1 0.0025 18.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ADK PF00406.22 PXF48671.1 - 0.0014 18.7 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA PF00004.29 PXF48671.1 - 0.0016 18.9 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 PXF48671.1 - 0.0024 17.4 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 PXF48671.1 - 0.0064 16.2 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PXF48671.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 PXF48671.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 PXF48671.1 - 0.015 15.7 0.0 0.052 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DnaB_C PF03796.15 PXF48671.1 - 0.034 13.5 0.0 0.08 12.3 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain CbiA PF01656.23 PXF48671.1 - 0.036 14.1 0.1 0.064 13.3 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 PXF48671.1 - 0.037 13.5 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase TsaE PF02367.17 PXF48671.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 PXF48671.1 - 0.046 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF48671.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain PMSR PF01625.21 PXF48671.1 - 0.088 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase AAA_5 PF07728.14 PXF48671.1 - 0.094 12.7 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PXF48671.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_26 PF13500.6 PXF48671.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 PXF48671.1 - 0.14 11.1 0.2 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin PF02224.18 PXF48671.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Cytidylate kinase Na_H_Exchanger PF00999.21 PXF48672.1 - 3.3e-65 220.4 38.1 5.6e-65 219.6 36.5 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 PXF48672.1 - 5.5e-14 52.4 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 PXF48672.1 - 0.019 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain STAT_alpha PF01017.20 PXF48673.1 - 0.05 13.5 3.5 0.038 13.9 1.8 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain Pro_isomerase PF00160.21 PXF48674.1 - 1.1e-23 84.3 0.0 1.5e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CAP_C PF08603.11 PXF48675.1 - 4.3e-51 172.6 8.4 5.2e-51 172.4 8.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 PXF48675.1 - 0.0025 17.4 8.0 0.0037 16.8 8.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 PXF48675.1 - 0.0067 16.1 4.9 0.011 15.4 4.4 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor C zf-UBP PF02148.19 PXF48676.1 - 1.6e-17 63.6 6.0 1.6e-17 63.6 6.0 2.1 2 1 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 PXF48676.1 - 1.9e-17 63.3 0.1 4.3e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 PXF48676.1 - 7.3e-08 32.6 5.2 7.3e-08 32.6 5.2 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF48676.1 - 3.3e-05 23.6 6.6 3.3e-05 23.6 6.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF48676.1 - 0.00011 22.1 0.9 0.00011 22.1 0.9 2.5 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF48676.1 - 0.00054 19.8 1.6 0.00054 19.8 1.6 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Golgin_A5 PF09787.9 PXF48676.1 - 0.0008 19.0 12.7 0.0012 18.4 12.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-rbx1 PF12678.7 PXF48676.1 - 0.0018 18.5 3.1 0.0018 18.5 3.1 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain Filament PF00038.21 PXF48676.1 - 0.0025 17.4 12.5 0.0044 16.7 12.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein Tup_N PF08581.10 PXF48676.1 - 0.0061 16.8 4.7 0.0061 16.8 4.7 2.2 1 1 1 2 2 2 1 Tup N-terminal zf-C3H2C3 PF17122.5 PXF48676.1 - 0.0089 16.0 4.5 0.02 14.9 4.5 1.7 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 PXF48676.1 - 0.019 15.0 3.4 0.048 13.7 3.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PXF48676.1 - 0.022 14.5 1.8 0.022 14.5 1.8 2.2 2 0 0 2 2 1 0 RING-like zinc finger CdhC PF03598.15 PXF48676.1 - 0.031 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit TACC_C PF05010.14 PXF48676.1 - 0.034 13.9 9.8 0.063 13.1 9.8 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_MLP1_2 PF07926.12 PXF48676.1 - 0.063 13.3 18.3 0.14 12.2 18.3 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 PXF48676.1 - 0.084 13.0 13.2 0.19 11.8 12.3 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 PXF48676.1 - 0.11 13.1 21.4 0.091 13.3 10.9 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 PXF48676.1 - 0.13 13.2 14.1 1.8 9.5 8.4 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PHF5 PF03660.14 PXF48676.1 - 0.19 11.9 4.8 0.42 10.8 4.8 1.5 1 0 0 1 1 1 0 PHF5-like protein BLOC1_2 PF10046.9 PXF48676.1 - 0.2 12.0 8.6 0.73 10.2 3.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 PXF48676.1 - 0.25 10.6 12.4 0.31 10.3 4.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) GAS PF13851.6 PXF48676.1 - 0.31 10.4 14.0 0.54 9.6 14.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-C3HC4_3 PF13920.6 PXF48676.1 - 0.54 10.2 16.7 0.088 12.7 4.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Seryl_tRNA_N PF02403.22 PXF48676.1 - 0.54 10.5 13.2 1.1 9.5 13.2 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 PXF48676.1 - 0.61 9.9 10.9 2.4 8.0 1.7 2.6 1 1 1 2 2 2 0 Septum formation initiator Tmemb_cc2 PF10267.9 PXF48676.1 - 0.62 9.2 10.7 2 7.5 10.8 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TMF_TATA_bd PF12325.8 PXF48676.1 - 1 9.6 16.1 4.2 7.6 1.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 PXF48676.1 - 1.1 9.3 19.5 0.41 10.7 7.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 PXF48676.1 - 1.6 8.0 8.4 2.6 7.3 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 PXF48676.1 - 1.8 7.7 5.7 3.2 6.9 5.7 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 PXF48676.1 - 1.9 8.3 9.8 4.9 6.9 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 PXF48676.1 - 2 7.2 15.7 3.8 6.3 15.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF5101 PF17031.5 PXF48676.1 - 2.3 8.4 8.4 2 8.6 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) DUF4200 PF13863.6 PXF48676.1 - 2.4 8.6 15.9 5.7 7.4 15.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 PXF48676.1 - 2.4 7.9 22.4 0.88 9.4 16.5 2.2 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH Takusan PF04822.13 PXF48676.1 - 2.6 8.0 11.0 1.3 8.9 2.0 2.7 2 0 0 2 2 2 0 Takusan Fib_alpha PF08702.10 PXF48676.1 - 2.7 8.2 6.2 10 6.3 0.2 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 PXF48676.1 - 4.4 7.3 14.2 2.6 8.1 1.8 2.5 1 1 1 2 2 2 0 Prefoldin subunit JIP_LZII PF16471.5 PXF48676.1 - 4.8 7.4 12.4 0.41 10.9 4.0 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Fungal_TACC PF12709.7 PXF48676.1 - 5.1 7.6 11.9 4.3 7.9 4.9 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prok-RING_4 PF14447.6 PXF48676.1 - 6 6.8 18.7 0.25 11.2 8.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Laminin_II PF06009.12 PXF48676.1 - 6.2 6.8 9.8 11 6.0 7.5 2.2 1 1 1 2 2 2 0 Laminin Domain II FapA PF03961.13 PXF48676.1 - 6.3 5.3 6.5 9.2 4.7 6.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 PXF48676.1 - 7.3 7.1 16.8 19 5.8 13.8 2.8 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 PXF48676.1 - 7.4 4.4 6.0 11 3.8 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 PXF48676.1 - 8.1 5.2 11.1 4.5 6.0 6.5 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 PXF48676.1 - 8.3 6.5 12.5 14 5.8 12.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fer2 PF00111.27 PXF48677.1 - 2.6e-13 49.7 0.1 3.1e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CoaE PF01121.20 PXF48678.1 - 1.3e-55 187.9 0.0 1.5e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 PXF48678.1 - 3.6e-06 27.5 0.0 7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain VraX PF17412.2 PXF48678.1 - 0.04 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function AAA_17 PF13207.6 PXF48678.1 - 0.092 13.2 0.0 8.1 6.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain UNC-50 PF05216.13 PXF48679.1 - 1.8e-81 272.9 23.5 2.1e-81 272.7 23.5 1.0 1 0 0 1 1 1 1 UNC-50 family Orf78 PF06024.12 PXF48679.1 - 4.1 7.8 5.5 1.9 8.8 0.2 2.5 3 0 0 3 3 3 0 Orf78 (ac78) Pyr_redox_2 PF07992.14 PXF48680.1 - 2.9e-44 151.5 0.0 3.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF48680.1 - 5.6e-10 39.3 0.0 0.001 18.7 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 PXF48680.1 - 2e-09 37.9 0.2 1.8e-05 25.2 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PXF48680.1 - 4.5e-09 36.5 0.1 0.035 14.1 0.0 3.5 3 0 0 3 3 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PXF48680.1 - 0.00032 20.9 0.2 0.14 12.4 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 PXF48680.1 - 0.001 18.2 0.2 8.2 5.4 0.0 3.2 3 0 0 3 3 3 3 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PXF48680.1 - 0.0019 17.3 0.3 1.7 7.6 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 PXF48680.1 - 0.011 14.9 0.0 2.5 7.1 0.0 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Spc7 PF08317.11 PXF48681.1 - 1.8e-07 30.3 4.1 2.7e-07 29.8 4.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 PXF48681.1 - 0.0051 16.4 0.7 0.013 15.1 0.7 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Vac_Fusion PF02346.16 PXF48681.1 - 0.058 13.0 0.3 0.23 11.1 0.3 2.0 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Spore_III_AB PF09548.10 PXF48681.1 - 1.1 9.4 3.6 0.71 10.0 1.4 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DnaJ PF00226.31 PXF48682.1 - 2.2e-18 66.1 2.0 1e-17 64.0 2.0 2.2 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 PXF48682.1 - 6e-16 58.4 0.4 1.5e-07 31.5 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF48682.1 - 1.4e-06 28.4 5.2 0.012 15.8 0.0 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Terminase_4 PF05119.12 PXF48682.1 - 0.15 12.5 7.5 8.1 7.0 4.7 3.0 2 1 0 2 2 2 0 Phage terminase, small subunit Borrelia_P83 PF05262.11 PXF48682.1 - 0.69 8.3 19.5 1.2 7.6 19.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 PXF48682.1 - 6 4.6 7.3 8.5 4.2 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0014 PF03649.13 PXF48683.1 - 2.9e-63 213.5 25.9 3.4e-63 213.2 25.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Mg_trans_NIPA PF05653.14 PXF48684.1 - 9.8e-69 231.7 14.8 2.1e-63 214.2 12.2 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 PXF48684.1 - 3.1e-07 30.7 5.2 3.1e-07 30.7 5.2 3.7 3 1 0 3 3 3 1 EamA-like transporter family CHGN PF05679.16 PXF48685.1 - 2.7e-54 184.9 0.1 4.2e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 PXF48685.1 - 0.0085 15.7 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Jacalin PF01419.17 PXF48686.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain Castor_Poll_mid PF06241.12 PXF48687.1 - 5.4e-25 87.4 0.0 1.3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel HTH_39 PF14090.6 PXF48687.1 - 0.0035 17.1 0.4 2.4 8.0 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain TrkA_C PF02080.21 PXF48687.1 - 0.012 15.4 0.0 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 TrkA-C domain DUF3159 PF11361.8 PXF48687.1 - 0.07 12.9 1.4 0.13 11.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) DUF2976 PF11190.8 PXF48687.1 - 0.11 12.3 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Metallophos_2 PF12850.7 PXF48688.1 - 7.9e-17 61.9 0.0 9.5e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GATase PF00117.28 PXF48688.1 - 0.15 11.8 0.8 10 5.8 0.2 2.1 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Ribosomal_S17e PF00833.18 PXF48689.1 - 1.3e-62 209.2 0.5 1.5e-62 208.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 Fimbrial PF00419.20 PXF48691.1 - 0.036 14.3 0.9 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Fimbrial protein COX6B PF02297.17 PXF48692.1 - 1.2e-17 63.9 6.0 1.3e-17 63.8 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb YozE_SAM_like PF06855.12 PXF48692.1 - 0.037 14.2 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 YozE SAM-like fold DUF1517 PF07466.11 PXF48693.1 - 6.4e-11 42.7 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) UDPG_MGDP_dh_N PF03721.14 PXF48694.1 - 1.9e-38 131.9 0.0 3.2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 PXF48694.1 - 5.9e-29 100.1 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 PXF48694.1 - 5.7e-20 71.7 0.0 8.9e-19 67.9 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 PXF48694.1 - 2.6e-06 27.7 0.0 6.7e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PXF48694.1 - 0.00041 20.3 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF48694.1 - 0.00042 19.7 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PXF48694.1 - 0.014 15.9 0.0 0.092 13.3 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 PXF48694.1 - 0.018 15.3 0.3 0.076 13.3 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain ApbA PF02558.16 PXF48694.1 - 0.026 14.2 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 PXF48694.1 - 0.057 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 PXF48694.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GGACT PF06094.12 PXF48695.1 - 2.4e-16 60.4 0.0 3.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PXF48695.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 0 AIG2-like family E3_UbLigase_R4 PF13764.6 PXF48696.1 - 4.6e-124 415.4 0.0 8.7e-124 414.5 0.0 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 PXF48696.1 - 0.0017 18.1 12.7 0.0017 18.1 12.7 4.2 3 1 1 4 4 4 1 Zinc finger, ZZ type E3_UbLigase_R4 PF13764.6 PXF48697.1 - 0.077 11.2 0.0 0.084 11.0 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 zf-C2H2_4 PF13894.6 PXF48698.1 - 1.3e-08 35.0 40.4 0.079 13.8 0.3 7.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF48698.1 - 2.9e-08 33.7 39.6 0.011 16.2 0.3 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-Di19 PF05605.12 PXF48698.1 - 0.00021 21.5 4.6 0.00021 21.5 4.6 3.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 PXF48698.1 - 0.00041 20.6 6.2 0.0061 16.9 0.3 7.6 8 1 0 8 8 7 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 PXF48698.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF48698.1 - 0.0055 17.0 2.9 1.1 9.6 0.0 4.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 PXF48698.1 - 0.0064 16.8 17.6 0.0091 16.3 3.9 2.7 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 PXF48698.1 - 0.018 15.7 19.4 0.11 13.2 1.5 4.7 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats ROS_MUCR PF05443.11 PXF48698.1 - 1.1 9.3 9.7 8.3 6.5 0.4 3.6 3 1 1 4 4 4 0 ROS/MUCR transcriptional regulator protein zf-met PF12874.7 PXF48698.1 - 1.4 9.5 9.9 24 5.5 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 PXF48698.1 - 2.4 8.1 6.5 0.37 10.7 0.1 2.8 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_aberr PF17017.5 PXF48698.1 - 6.9 6.8 8.6 3.7 7.7 2.8 2.8 2 1 1 3 3 3 0 Aberrant zinc-finger NUDIX_4 PF14815.6 PXF48699.1 - 1.1e-18 67.2 0.0 3e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 PXF48699.1 - 2.7e-18 66.4 0.0 5.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PXF48699.1 - 0.00092 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif NUDIX PF00293.28 PXF48699.1 - 0.039 14.0 0.4 0.066 13.3 0.4 1.3 1 0 0 1 1 1 0 NUDIX domain Phage_TAC_1 PF06222.11 PXF48699.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone BES1_N PF05687.13 PXF48699.1 - 2 8.8 7.4 30 5.0 5.8 2.3 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal DUF778 PF05608.12 PXF48701.1 - 0.71 10.2 3.5 1.4 9.2 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Clat_adaptor_s PF01217.20 PXF48702.1 - 4.3e-16 59.1 0.3 5.5e-16 58.8 0.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3510 PF12022.8 PXF48703.1 - 9.2e-26 90.7 0.8 7.6e-25 87.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 PXF48703.1 - 1.5e-16 60.7 0.3 5.7e-16 58.8 0.3 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF5063 PF16702.5 PXF48703.1 - 0.0037 17.7 1.6 0.062 13.7 0.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5063) Baculo_PEP_C PF04513.12 PXF48703.1 - 0.0052 16.8 8.1 0.054 13.5 2.2 3.9 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 PXF48703.1 - 0.043 13.5 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4795 PF16043.5 PXF48703.1 - 0.06 13.0 0.9 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) HTH_36 PF13730.6 PXF48703.1 - 0.095 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Syntaxin_2 PF14523.6 PXF48703.1 - 0.11 12.8 1.2 0.78 10.1 1.0 2.6 1 1 1 2 2 2 0 Syntaxin-like protein Vps51 PF08700.11 PXF48703.1 - 0.28 11.3 4.3 0.44 10.7 0.2 3.2 2 1 1 3 3 3 0 Vps51/Vps67 Syntaxin-6_N PF09177.11 PXF48703.1 - 0.92 10.1 6.8 0.48 11.0 0.3 3.6 2 2 1 4 4 4 0 Syntaxin 6, N-terminal MukF_M PF17192.4 PXF48703.1 - 1.3 8.7 4.7 3.2 7.5 0.3 3.1 2 1 1 3 3 3 0 MukF middle domain DUF948 PF06103.11 PXF48703.1 - 4.9 7.5 6.2 1.2 9.4 0.4 3.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF5513 PF17632.2 PXF48704.1 - 0.055 13.9 0.1 0.11 12.9 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5513) DUF1053 PF06327.14 PXF48704.1 - 0.1 13.2 1.6 0.22 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF4200 PF13863.6 PXF48705.1 - 0.0035 17.7 5.1 0.0035 17.7 5.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) SlyX PF04102.12 PXF48705.1 - 0.011 16.3 0.2 0.011 16.3 0.2 3.9 3 1 0 3 3 3 0 SlyX UPF0242 PF06785.11 PXF48705.1 - 0.021 14.9 5.1 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MapZ_EC1 PF18041.1 PXF48705.1 - 0.73 10.1 4.7 1.3 9.3 4.1 1.7 2 0 0 2 2 2 0 MapZ extracellular domain 1 Peptidase_M16 PF00675.20 PXF48706.1 - 7.7e-43 146.0 0.0 1.9e-42 144.7 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PXF48706.1 - 1.7e-33 116.2 0.0 3.6e-31 108.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ish1 PF10281.9 PXF48706.1 - 0.085 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Malectin PF11721.8 PXF48707.1 - 1.8e-17 63.9 0.0 2.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Malectin domain MGC-24 PF05283.11 PXF48707.1 - 2.9 8.3 7.2 5.9 7.3 7.2 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin UQ_con PF00179.26 PXF48708.1 - 4.8e-28 97.6 0.0 5.2e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 PXF48708.1 - 0.053 12.4 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DUF846 PF05832.12 PXF48709.1 - 5e-50 169.2 12.1 7e-50 168.7 12.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) RseC_MucC PF04246.12 PXF48709.1 - 7.3 6.6 6.5 8.9 6.3 0.3 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HEAT PF02985.22 PXF48710.1 - 0.045 14.0 0.4 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat Ribosomal_L18 PF17135.4 PXF48711.1 - 8.7e-86 286.1 1.4 9.8e-86 285.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 PXF48711.1 - 0.0001 23.0 0.0 0.00023 21.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF724 PF05266.14 PXF48712.1 - 0.64 9.8 15.0 0.025 14.4 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 PXF48712.1 - 3 7.8 11.1 3.2 7.7 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DivIVA PF05103.13 PXF48712.1 - 7 6.7 15.4 2.4 8.3 0.9 2.7 2 1 0 2 2 2 0 DivIVA protein SecY PF00344.20 PXF48713.1 - 3.9e-71 239.8 12.1 4.7e-71 239.5 12.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 PXF48713.1 - 8.2e-16 57.5 0.4 3.4e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Claudin_3 PF06653.11 PXF48713.1 - 0.00039 20.4 0.7 0.057 13.4 0.0 2.8 2 0 0 2 2 2 2 Tight junction protein, Claudin-like zf-RING_2 PF13639.6 PXF48714.1 - 1.3e-10 41.4 8.0 2.3e-10 40.6 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF48714.1 - 8.9e-09 35.1 8.4 1.7e-08 34.2 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF48714.1 - 8.6e-07 29.2 6.1 2.2e-06 27.8 6.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF48714.1 - 1.9e-06 27.7 6.0 3.5e-06 26.8 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF48714.1 - 4.1e-06 26.6 4.2 6.9e-06 25.8 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF48714.1 - 4.5e-06 26.6 2.8 5.7e-06 26.3 1.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PXF48714.1 - 6.3e-05 22.8 5.8 0.00011 22.0 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PXF48714.1 - 8e-05 22.3 7.2 8e-05 22.3 7.2 2.2 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 PXF48714.1 - 0.00064 19.5 5.0 0.0012 18.7 5.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF48714.1 - 0.1 12.7 2.5 0.21 11.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pex14_N PF04695.13 PXF48714.1 - 0.11 13.1 2.3 0.24 12.1 0.3 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_4 PF14570.6 PXF48714.1 - 0.31 10.9 5.6 0.54 10.1 5.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 PXF48714.1 - 0.67 10.2 5.6 1.4 9.1 5.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.31 PXF48715.1 - 1.3e-11 44.5 0.6 2.1e-11 43.8 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF48715.1 - 0.0052 17.0 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF48715.1 - 0.13 12.2 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Myb DNA-binding like DUF4602 PF15375.6 PXF48716.1 - 4.4e-12 46.5 9.1 7.3e-12 45.8 9.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Lum_binding PF00677.17 PXF48717.1 - 2.3e-47 158.9 4.0 1.9e-23 82.2 0.5 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF452 PF04301.13 PXF48717.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) DUF1168 PF06658.12 PXF48718.1 - 2.5e-15 56.5 27.9 6.5e-15 55.1 27.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4407 PF14362.6 PXF48718.1 - 3.2 7.0 8.8 4.7 6.5 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 PXF48718.1 - 4.3 7.0 14.7 0.14 11.9 8.3 1.6 2 0 0 2 2 2 0 AAA domain Tubulin PF00091.25 PXF48719.1 - 5.7e-69 232.3 0.0 1e-68 231.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PXF48719.1 - 3.6e-35 120.9 0.0 5.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PXF48719.1 - 0.0002 21.1 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 PXF48719.1 - 0.00081 19.7 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PXF48719.1 - 0.0049 16.1 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin like bZIP_2 PF07716.15 PXF48720.1 - 9.2e-06 25.6 6.6 9.2e-06 25.6 6.6 3.2 2 1 2 4 4 4 2 Basic region leucine zipper bZIP_1 PF00170.21 PXF48720.1 - 2.7e-05 24.1 8.0 2.7e-05 24.1 8.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor APG6_N PF17675.1 PXF48720.1 - 0.097 13.2 11.9 0.18 12.3 11.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 PXF48720.1 - 0.38 11.1 7.1 2.6 8.4 3.0 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family SHE3 PF17078.5 PXF48720.1 - 0.47 10.1 10.4 0.73 9.5 10.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 PXF48720.1 - 0.71 10.1 4.2 1.5 9.1 4.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 PXF48720.1 - 1.4 9.2 10.1 1.1 9.4 1.6 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4071 PF13281.6 PXF48720.1 - 1.4 7.9 5.3 2.1 7.3 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Xpo1 PF08389.12 PXF48721.1 - 9.2e-22 77.7 1.6 3.9e-18 65.9 0.0 3.3 2 0 0 2 2 2 2 Exportin 1-like protein CLASP_N PF12348.8 PXF48721.1 - 0.014 15.0 1.8 0.59 9.7 0.6 2.7 2 0 0 2 2 2 0 CLASP N terminal ParcG PF10274.9 PXF48721.1 - 0.024 14.8 1.2 4.6 7.3 0.0 3.9 4 0 0 4 4 4 0 Parkin co-regulated protein DUF3385 PF11865.8 PXF48721.1 - 0.21 11.5 4.8 4 7.3 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) Chloroa_b-bind PF00504.21 PXF48723.1 - 3.5e-09 37.4 0.1 7.5e-09 36.3 0.1 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Fe-S_biosyn PF01521.20 PXF48724.1 - 1.5e-18 67.0 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aconitase PF00330.20 PXF48725.1 - 6.4e-153 510.0 0.0 8.3e-153 509.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PXF48725.1 - 1.4e-44 151.6 0.0 2.7e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ubiquitin PF00240.23 PXF48726.1 - 2.9e-201 651.7 37.3 4.6e-33 112.8 0.8 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 PXF48726.1 - 2e-94 309.5 36.4 3.3e-15 55.7 0.7 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PXF48726.1 - 9.8e-34 115.7 20.7 0.00044 20.6 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 PXF48726.1 - 7.7e-22 77.0 12.4 0.054 13.4 0.1 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PXF48726.1 - 9.3e-20 70.8 8.6 0.23 11.6 0.0 7.1 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PXF48726.1 - 1.6e-19 70.4 6.1 0.37 11.4 0.0 6.2 1 1 3 6 6 6 6 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PXF48726.1 - 1.9e-19 69.8 19.1 0.074 13.4 0.1 6.1 6 0 0 6 6 6 6 Ubiquitin-like domain Methyltrans_RNA PF04452.14 PXF48726.1 - 1.9e-10 40.5 5.2 1.9 7.8 0.0 5.2 5 0 0 5 5 5 5 RNA methyltransferase DUF3861 PF12977.7 PXF48726.1 - 4e-09 36.5 8.1 14 6.0 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 PXF48726.1 - 7.8e-09 35.8 0.0 50 4.4 0.0 6.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 PXF48726.1 - 2e-08 34.1 41.9 21 5.3 0.2 11.9 12 0 0 12 12 12 0 Ubiquitin-like domain Big_7 PF17957.1 PXF48726.1 - 1.4e-07 32.1 0.3 94 3.9 0.0 6.1 6 0 0 6 6 6 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 PXF48726.1 - 6.6e-07 29.4 14.2 6.7 6.9 0.1 5.9 6 0 0 6 6 6 5 UDP-glucose:Glycoprotein Glucosyltransferase Big_3_3 PF13750.6 PXF48726.1 - 7.2e-07 29.0 0.1 54 3.4 0.0 5.8 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 PXF48726.1 - 1e-06 28.4 0.3 34 3.7 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 PXF48726.1 - 7.6e-05 23.2 4.2 1.5e+02 3.0 0.0 6.1 6 0 0 6 6 6 0 ACT domain ACT_5 PF13710.6 PXF48726.1 - 0.00014 21.6 12.2 41 4.1 0.1 6.2 6 0 0 6 6 6 0 ACT domain ORF11CD3 PF10549.9 PXF48726.1 - 0.00015 21.8 3.2 1.5e+02 2.6 0.0 7.3 12 0 0 12 12 6 0 ORF11CD3 domain YcgR_2 PF12945.7 PXF48726.1 - 0.00016 21.8 14.1 41 4.4 0.1 6.2 6 0 0 6 6 6 0 Flagellar protein YcgR DUF493 PF04359.14 PXF48726.1 - 0.0013 19.2 0.8 3.8e+02 1.7 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF493) NEAT PF05031.12 PXF48726.1 - 0.0015 19.1 12.1 5.9 7.5 0.4 4.6 1 1 3 4 4 4 3 Iron Transport-associated domain Phage-tail_1 PF09097.10 PXF48726.1 - 0.02 14.7 2.3 2.5e+02 1.3 0.0 5.3 6 0 0 6 6 6 0 Baseplate structural protein, domain 1 Tash_PEST PF07708.11 PXF48726.1 - 0.3 11.3 44.7 9.8 6.5 1.4 6.4 6 0 0 6 6 6 0 Tash protein PEST motif ProRS-C_2 PF09181.10 PXF48726.1 - 0.43 10.8 14.4 1.6e+02 2.5 0.1 5.9 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal Ribosomal_L28 PF00830.19 PXF48727.1 - 4e-19 68.5 1.0 6.6e-19 67.9 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family PAP2 PF01569.21 PXF48728.1 - 0.036 13.8 0.0 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily 2OG-FeII_Oxy_3 PF13640.6 PXF48730.1 - 3.3e-12 47.1 0.0 5.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PXF48730.1 - 0.017 15.6 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_2 PF13532.6 PXF48730.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pyr_redox_2 PF07992.14 PXF48732.1 - 1.1e-56 192.2 1.2 1.4e-56 191.9 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PXF48732.1 - 2.6e-30 104.9 0.1 6.6e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PXF48732.1 - 2.3e-15 56.9 0.4 3.4e-12 46.8 0.0 3.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF48732.1 - 2.1e-08 33.7 5.9 6.2e-08 32.1 2.5 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PXF48732.1 - 4.7e-07 29.2 5.5 0.0037 16.4 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 PXF48732.1 - 0.00012 22.0 0.2 0.13 12.1 0.4 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 PXF48732.1 - 0.00056 19.2 0.0 0.0054 15.9 0.0 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PXF48732.1 - 0.00062 19.9 2.2 0.0075 16.5 1.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PXF48732.1 - 0.00099 18.6 2.9 0.0043 16.5 2.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PXF48732.1 - 0.0078 15.5 0.8 0.012 14.9 0.2 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 PXF48732.1 - 0.019 14.6 5.1 0.019 14.6 5.1 3.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PXF48732.1 - 0.048 12.9 3.0 6.5 5.9 2.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 PXF48732.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF48732.1 - 0.083 12.2 0.1 2.2 7.6 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 PXF48732.1 - 0.22 11.5 2.0 1.1 9.3 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DEAD PF00270.29 PXF48733.1 - 1e-38 132.8 0.0 1.8e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF48733.1 - 2.5e-26 92.2 0.0 8.9e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PXF48733.1 - 2.5e-16 59.6 0.1 5.5e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PXF48733.1 - 2.4e-07 30.9 0.0 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF48733.1 - 0.015 15.6 0.2 0.08 13.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain Rhodanese PF00581.20 PXF48734.1 - 1e-21 77.5 0.0 8.9e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Tweety PF04906.13 PXF48735.1 - 0.00068 18.4 6.6 0.00068 18.4 6.6 2.3 2 1 0 2 2 2 2 Tweety TGT PF01702.18 PXF48736.1 - 2.5e-38 132.2 0.0 3.2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Lentiviral_Tat PF02998.14 PXF48736.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Lentiviral Tat protein PMT_4TMC PF16192.5 PXF48737.1 - 7.2e-40 136.7 12.8 7.2e-40 136.7 12.8 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase T4SS_CagC PF16943.5 PXF48737.1 - 0.046 13.9 6.4 0.06 13.5 0.0 3.1 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system DUF3923 PF13061.6 PXF48737.1 - 0.088 12.9 0.1 0.088 12.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) SUR7 PF06687.12 PXF48737.1 - 0.21 11.2 6.1 0.22 11.1 0.2 2.4 2 0 0 2 2 2 0 SUR7/PalI family DUF2626 PF11117.8 PXF48737.1 - 0.57 10.9 4.3 3.9 8.3 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2626) Aminotran_1_2 PF00155.21 PXF48738.1 - 7.8e-40 137.2 0.0 1.1e-39 136.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PXF48738.1 - 0.0033 16.7 0.0 0.01 15.1 0.0 1.7 1 1 1 2 2 2 1 Beta-eliminating lyase Spherulin4 PF12138.8 PXF48738.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Spherulation-specific family 4 Aminotran_5 PF00266.19 PXF48738.1 - 0.071 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V CpeS PF09367.10 PXF48739.1 - 4.9e-24 85.1 0.1 6e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 CpeS-like protein EpmC PF04315.12 PXF48739.1 - 0.0057 16.4 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P hydroxylase SWIB PF02201.18 PXF48740.1 - 2.4e-47 158.7 0.2 1.2e-24 86.0 0.0 3.3 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 PXF48740.1 - 6.2e-10 38.9 1.3 1.1e-09 38.1 0.5 1.9 2 0 0 2 2 2 1 DEK C terminal domain Acetyltransf_10 PF13673.7 PXF48743.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 PXF48745.1 - 9.9e-13 48.3 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 PXF48745.1 - 6.8e-12 45.7 0.1 1.3e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF48745.1 - 3.8e-07 30.4 0.2 8.2e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PXF48745.1 - 9e-05 22.4 0.1 0.0002 21.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PXF48745.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PBS_linker_poly PF00427.21 PXF48746.1 - 3.1e-42 143.6 0.1 8.2e-42 142.2 0.1 1.7 2 0 0 2 2 2 1 Phycobilisome Linker polypeptide DIX PF00778.17 PXF48746.1 - 0.039 13.8 0.0 0.22 11.4 0.0 2.2 2 1 0 2 2 2 0 DIX domain DUF5082 PF16888.5 PXF48746.1 - 0.056 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF572 PF04502.13 PXF48747.1 - 1.6e-62 212.1 21.1 1e-60 206.2 20.5 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 PXF48747.1 - 0.0043 17.0 2.4 0.0043 17.0 1.1 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 PXF48747.1 - 0.029 13.9 1.5 0.029 13.9 1.5 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 PXF48747.1 - 0.15 12.0 2.4 15 5.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-PHD-like PF15446.6 PXF48747.1 - 1 9.0 7.7 0.51 9.9 2.6 2.4 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Tubulin PF00091.25 PXF48748.1 - 1.8e-71 240.4 0.1 1e-69 234.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PXF48748.1 - 8e-27 93.9 0.0 9.5e-24 84.0 0.0 2.3 1 1 1 2 2 2 2 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PXF48748.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PXF48748.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 PXF48748.1 - 0.078 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like LMWPc PF01451.21 PXF48750.1 - 1.1e-27 97.2 0.0 1.9e-26 93.2 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ribonuclease_3 PF00636.26 PXF48751.1 - 4.5e-36 123.7 0.0 1.7e-16 60.8 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 PXF48751.1 - 6.8e-29 100.6 0.0 2.9e-13 50.1 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 PXF48751.1 - 6.2e-16 58.7 0.0 1.5e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48751.1 - 5.6e-14 52.5 0.0 9.3e-09 35.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF48751.1 - 2e-12 47.2 0.1 3.9e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 PXF48751.1 - 2.7e-12 46.7 0.0 7.4e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.22 PXF48751.1 - 1.5e-06 28.1 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.26 PXF48751.1 - 3e-06 27.9 0.0 0.0017 19.0 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif ImcF-related_N PF14331.6 PXF48751.1 - 0.098 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_22 PF13401.6 PXF48751.1 - 0.2 11.9 0.9 19 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain ANAPC10 PF03256.16 PXF48752.1 - 2.9e-48 164.0 1.1 5.1e-48 163.2 1.1 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 PXF48752.1 - 0.00021 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain U1snRNP70_N PF12220.8 PXF48752.1 - 0.017 15.8 1.9 0.032 14.9 1.9 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 PXF48753.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 PXF48754.1 - 2.1e-07 30.7 0.2 4.6e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 G-patch domain Pkinase PF00069.25 PXF48755.1 - 6.6e-70 235.5 0.0 8.5e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48755.1 - 1.6e-37 129.2 0.0 6.3e-37 127.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF48755.1 - 4.7e-06 26.1 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF48755.1 - 0.00011 21.6 0.0 0.00082 18.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PXF48755.1 - 0.012 15.5 1.4 0.054 13.4 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF48755.1 - 0.034 13.1 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4729 PF15866.5 PXF48755.1 - 0.036 13.4 0.3 0.067 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Pkinase_fungal PF17667.1 PXF48755.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase AAA PF00004.29 PXF48756.1 - 1.7e-56 190.2 0.0 5e-41 140.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF48756.1 - 1.1e-11 44.3 0.1 2.7e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PXF48756.1 - 2.7e-10 40.7 0.3 0.0004 20.7 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 PXF48756.1 - 4.6e-10 40.1 0.1 0.0034 17.8 0.0 3.6 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 PXF48756.1 - 5.4e-09 36.4 0.1 1.1e-06 28.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PXF48756.1 - 9.8e-09 35.3 0.2 0.00036 20.5 0.0 3.4 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PXF48756.1 - 5e-08 32.8 0.0 0.0074 16.0 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PXF48756.1 - 6.7e-08 32.8 0.0 0.013 15.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 PXF48756.1 - 6.9e-08 33.1 0.0 0.025 15.1 0.0 3.0 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 PXF48756.1 - 1e-07 31.5 0.0 0.0051 16.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 PXF48756.1 - 9.9e-07 28.7 0.0 0.011 15.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 PXF48756.1 - 1.4e-06 28.4 0.1 5.9e-05 23.2 0.0 3.4 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 PXF48756.1 - 2.4e-06 27.1 0.3 0.0062 16.0 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PXF48756.1 - 7.5e-06 26.0 0.0 0.026 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PXF48756.1 - 1.3e-05 25.6 0.0 0.018 15.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 PXF48756.1 - 1.5e-05 24.5 0.3 0.013 14.9 0.1 2.7 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 PXF48756.1 - 1.7e-05 25.1 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PXF48756.1 - 3.6e-05 23.7 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 PXF48756.1 - 4.2e-05 23.0 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 PXF48756.1 - 4.7e-05 23.2 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 PXF48756.1 - 7.6e-05 22.7 0.2 0.21 11.6 0.0 3.2 3 1 1 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 PXF48756.1 - 0.00017 21.2 0.1 0.02 14.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 PXF48756.1 - 0.00017 21.5 0.0 0.28 11.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PXF48756.1 - 0.00021 21.0 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 PXF48756.1 - 0.00026 20.5 0.1 0.37 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 PXF48756.1 - 0.00033 21.2 1.3 0.019 15.5 0.2 2.7 2 0 0 2 2 2 1 ABC transporter ResIII PF04851.15 PXF48756.1 - 0.00048 20.2 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 PXF48756.1 - 0.0007 19.2 2.9 2 7.9 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 PXF48756.1 - 0.00072 19.3 0.1 0.87 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PXF48756.1 - 0.0012 19.2 0.0 0.52 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PXF48756.1 - 0.0016 18.4 0.0 3.3 7.6 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain NB-ARC PF00931.22 PXF48756.1 - 0.0055 15.9 0.1 0.46 9.6 0.1 2.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 PXF48756.1 - 0.0057 16.6 3.7 0.64 9.9 0.0 3.2 4 0 0 4 4 3 1 NACHT domain Parvo_NS1 PF01057.17 PXF48756.1 - 0.0088 15.2 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 PXF48756.1 - 0.011 16.2 0.1 5.6 7.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 PXF48756.1 - 0.019 14.2 0.0 0.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 PXF48756.1 - 0.037 14.2 0.0 9.5 6.3 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 PXF48756.1 - 0.064 12.6 0.0 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 Isopentenyl transferase Cytidylate_kin PF02224.18 PXF48756.1 - 0.068 12.9 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase ATPase_2 PF01637.18 PXF48756.1 - 0.075 12.9 0.4 6.1 6.7 0.1 3.2 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 PXF48756.1 - 0.082 12.3 0.2 5.3 6.4 0.2 3.1 2 1 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 PXF48756.1 - 0.13 12.2 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 PXF48756.1 - 0.13 12.0 0.1 23 4.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 PXF48756.1 - 0.2 11.5 0.0 2.1 8.2 0.0 2.5 3 0 0 3 3 3 0 Deoxynucleoside kinase Sgf11 PF08209.11 PXF48757.1 - 6.1e-13 48.1 1.6 1.1e-12 47.2 1.6 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Nha1_C PF08619.10 PXF48757.1 - 0.0067 15.7 7.2 0.017 14.3 0.2 2.1 2 0 0 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus zf-CpG_bind_C PF12269.8 PXF48757.1 - 0.021 14.6 0.3 0.034 13.9 0.3 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain TPR_MLP1_2 PF07926.12 PXF48758.1 - 0.00014 21.9 16.6 0.00014 21.9 16.6 3.1 2 1 2 4 4 4 3 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 PXF48758.1 - 0.0011 19.2 39.0 0.02 15.2 7.0 3.1 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 PXF48758.1 - 0.012 16.0 15.5 0.015 15.6 0.3 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.11 PXF48758.1 - 0.028 13.3 29.3 1.1 8.0 20.2 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 PXF48758.1 - 0.16 12.0 35.2 0.36 10.9 11.1 3.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF496 PF04363.12 PXF48758.1 - 0.41 10.7 0.1 0.41 10.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF496) HIP1_clath_bdg PF16515.5 PXF48758.1 - 0.45 11.2 29.4 4.2 8.0 3.5 4.2 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 PXF48758.1 - 0.58 9.6 27.8 2.3 7.6 13.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 PXF48758.1 - 0.87 9.8 32.8 0.14 12.3 10.2 3.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 PXF48758.1 - 1 9.6 26.4 3.5 7.9 3.1 4.2 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 ApoO PF09769.9 PXF48758.1 - 1 9.4 5.0 1.9 8.4 0.2 3.0 3 1 0 3 3 3 0 Apolipoprotein O YabA PF06156.13 PXF48758.1 - 2.3 8.9 24.0 0.14 12.8 1.8 4.1 1 1 2 3 3 3 0 Initiation control protein YabA Cep57_CLD PF14073.6 PXF48758.1 - 4.3 7.3 29.0 0.8 9.7 9.2 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 APG6_N PF17675.1 PXF48758.1 - 5.8 7.4 35.5 4.1 7.9 7.9 4.0 1 1 3 4 4 4 0 Apg6 coiled-coil region GED PF02212.18 PXF48758.1 - 5.8 7.1 15.9 2.6 8.3 0.2 4.0 4 0 0 4 4 4 0 Dynamin GTPase effector domain Rootletin PF15035.6 PXF48758.1 - 6.4 6.7 31.2 5.3 7.0 14.0 3.1 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion PMI_typeI PF01238.21 PXF48760.1 - 2.3e-98 329.8 0.0 3.1e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF3306 PF11748.8 PXF48760.1 - 0.077 13.9 0.1 0.14 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) AraC_binding PF02311.19 PXF48760.1 - 0.12 12.3 0.0 10 6.0 0.0 2.9 3 0 0 3 3 3 0 AraC-like ligand binding domain Pep3_Vps18 PF05131.14 PXF48762.1 - 3.9e-10 39.7 0.0 0.00028 20.7 0.0 2.7 2 0 0 2 2 2 2 Pep3/Vps18/deep orange family DUF3138 PF11336.8 PXF48763.1 - 0.045 12.4 8.9 0.058 12.0 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 PXF48763.1 - 0.075 13.6 5.2 0.2 12.3 5.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein FSA_C PF10479.9 PXF48763.1 - 0.33 9.0 3.1 0.39 8.8 3.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Adeno_PV PF03910.13 PXF48763.1 - 2.4 6.8 13.3 0.77 8.4 10.3 1.5 1 1 1 2 2 2 0 Adenovirus minor core protein PV CREPT PF16566.5 PXF48763.1 - 4.6 7.4 9.5 0.23 11.6 1.3 2.4 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour UQ_con PF00179.26 PXF48764.1 - 5.3e-49 165.5 0.0 6e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF48764.1 - 1.5e-05 24.8 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 PXF48764.1 - 0.021 14.7 0.1 0.047 13.6 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 PXF48764.1 - 0.092 13.0 0.2 0.12 12.6 0.2 1.5 1 1 0 1 1 1 0 RWD domain Pro_isomerase PF00160.21 PXF48765.1 - 9e-19 68.3 0.0 1.5e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1357 PF07094.11 PXF48765.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Beta_protein PF14350.6 PXF48765.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Beta protein ThiF PF00899.21 PXF48766.1 - 4.5e-63 212.8 0.0 6.7e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 PXF48766.1 - 3.2e-15 56.0 0.1 5.2e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 PXF48766.1 - 0.09 12.8 0.3 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Adaptin_N PF01602.20 PXF48767.1 - 2.2e-86 290.5 5.5 5e-78 262.9 3.2 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 PXF48767.1 - 2e-14 53.9 2.4 5.8e-08 32.9 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 PXF48767.1 - 9.1e-05 22.6 1.4 0.059 13.6 0.0 3.7 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 PXF48767.1 - 0.00037 20.8 7.0 3.6 8.0 0.1 5.1 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 PXF48767.1 - 0.00045 20.2 1.5 15 6.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Proteasom_PSMB PF10508.9 PXF48767.1 - 0.14 10.6 1.8 8.9 4.7 0.2 2.8 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit Ribosomal_L33 PF00471.20 PXF48768.1 - 4.9e-11 42.9 0.1 9e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 PRA-CH PF01502.18 PXF48769.1 - 1.2e-32 111.6 0.1 1.8e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Ribosomal_L3 PF00297.22 PXF48770.1 - 1.3e-24 86.9 4.3 1.1e-21 77.3 3.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 BRCT_2 PF16589.5 PXF48772.1 - 0.061 13.7 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain zf-C2H2 PF00096.26 PXF48773.1 - 5.3e-15 54.9 25.6 0.00057 20.2 2.7 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF48773.1 - 6.4e-13 48.4 25.6 0.0015 19.2 1.8 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF48773.1 - 4.5e-11 42.7 28.2 0.00046 20.5 0.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 PXF48773.1 - 1.6e-05 25.1 12.6 0.012 15.9 3.5 2.5 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 PXF48773.1 - 0.0016 18.4 24.0 0.28 11.2 0.8 4.7 4 1 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 PXF48773.1 - 0.009 15.8 0.2 0.009 15.8 0.2 5.4 4 2 0 4 4 3 1 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 PXF48773.1 - 0.013 16.2 7.7 3.5 8.3 7.8 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats RNA_POL_M_15KD PF02150.16 PXF48773.1 - 0.015 15.2 7.5 0.83 9.6 0.1 4.0 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-C2H2_11 PF16622.5 PXF48773.1 - 0.034 13.9 15.0 0.37 10.6 0.5 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-MYST PF17772.1 PXF48773.1 - 0.068 12.8 6.5 0.14 11.8 0.1 3.3 2 1 2 4 4 4 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 PXF48773.1 - 0.091 12.4 11.0 2.3 7.9 0.6 3.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 PXF48773.1 - 0.14 11.7 10.3 1.1 8.9 0.0 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 PXF48773.1 - 1.1 9.7 10.2 4.2 7.9 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 PXF48773.1 - 5.8 7.5 20.0 1.8e+04 -5.8 20.0 3.9 1 1 0 1 1 0 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 PXF48773.1 - 7.1 7.0 15.0 5.9 7.3 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding HypA PF01155.19 PXF48773.1 - 8.7 6.4 8.2 1.8e+02 2.1 8.2 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3275 PF11679.8 PXF48774.1 - 0.0071 16.4 0.2 0.0088 16.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3275) DUF948 PF06103.11 PXF48774.1 - 0.17 12.1 1.8 0.24 11.7 1.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) S1 PF00575.23 PXF48776.1 - 2.9e-30 104.4 6.6 3.7e-15 56.0 0.4 3.1 3 1 0 3 3 3 2 S1 RNA binding domain RNase_II_C_S1 PF18614.1 PXF48776.1 - 0.00022 21.1 2.4 0.052 13.5 0.5 2.7 2 0 0 2 2 2 2 RNase II-type exonuclease C-terminal S1 domain NOC3p PF07540.11 PXF48777.1 - 6.9e-26 90.5 0.4 2e-25 89.0 0.4 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 PXF48777.1 - 5.6e-13 49.3 0.0 2.1e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 CBF/Mak21 family PGA2 PF07543.12 PXF48777.1 - 0.12 12.3 11.6 1.7 8.6 4.1 2.9 2 0 0 2 2 2 0 Protein trafficking PGA2 SET PF00856.28 PXF48778.1 - 7.7e-05 23.1 0.0 0.003 18.0 0.0 2.9 1 1 0 1 1 1 1 SET domain TCR PF03638.15 PXF48778.1 - 7 7.1 34.1 9.7 6.6 15.4 2.8 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain TPR_14 PF13428.6 PXF48779.1 - 3.3e-42 139.5 55.6 9.3e-05 22.9 0.8 18.3 3 1 17 20 20 19 13 Tetratricopeptide repeat TPR_2 PF07719.17 PXF48779.1 - 3.1e-40 133.0 31.7 0.011 15.8 0.0 18.3 17 1 1 18 18 18 9 Tetratricopeptide repeat TPR_19 PF14559.6 PXF48779.1 - 2.2e-33 114.6 16.4 0.0044 17.5 0.0 10.8 9 2 2 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 PXF48779.1 - 8e-30 101.1 9.3 0.089 13.2 0.0 13.7 16 0 0 16 16 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 PXF48779.1 - 8.5e-30 103.1 65.2 0.00017 22.2 6.7 11.2 8 3 2 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 PXF48779.1 - 2.2e-23 82.3 45.2 0.00048 20.4 0.6 12.4 8 5 3 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 PXF48779.1 - 3.6e-20 70.4 0.0 0.41 11.0 0.0 13.3 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_1 PF00515.28 PXF48779.1 - 8.2e-17 60.2 4.5 0.37 10.7 0.0 13.1 13 0 0 13 13 13 2 Tetratricopeptide repeat Suf PF05843.14 PXF48779.1 - 1.5e-13 51.4 0.0 0.0078 16.2 0.0 6.0 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 PXF48779.1 - 1.7e-13 50.5 18.1 0.00012 21.4 0.1 8.1 1 1 6 9 9 9 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF48779.1 - 5.8e-10 39.2 6.8 5 7.1 0.0 10.0 12 1 1 13 13 12 1 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 PXF48779.1 - 2e-09 37.0 5.3 1.3 8.8 0.0 8.9 10 0 0 10 10 9 2 TPR repeat MIT PF04212.18 PXF48779.1 - 3.2e-08 33.5 5.9 1 9.5 0.2 6.8 6 1 0 6 6 5 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PXF48779.1 - 5.6e-08 32.9 28.4 17 6.3 0.0 13.0 13 2 2 15 15 13 0 Tetratricopeptide repeat TPR_9 PF13371.6 PXF48779.1 - 3.7e-06 27.0 41.8 0.51 10.5 0.1 9.9 7 3 5 12 12 12 4 Tetratricopeptide repeat NARP1 PF12569.8 PXF48779.1 - 1.4e-05 24.2 0.8 0.0038 16.2 0.0 4.0 4 2 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 PXF48779.1 - 1.7e-05 24.5 18.0 0.41 10.8 0.0 9.8 14 0 0 14 14 8 1 Tetratricopeptide repeat PPR PF01535.20 PXF48779.1 - 0.00038 20.5 11.0 18 5.9 0.2 9.6 13 0 0 13 13 7 0 PPR repeat Fis1_TPR_C PF14853.6 PXF48779.1 - 0.00072 19.6 3.3 1.4 9.1 0.0 5.2 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 PXF48779.1 - 0.0014 18.4 51.5 1.4 8.9 2.4 13.6 16 0 0 16 16 15 1 Tetratricopeptide repeat DUF2802 PF10975.8 PXF48779.1 - 0.0066 16.6 1.2 3.8 7.7 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2802) Peptidase_M13_N PF05649.13 PXF48779.1 - 0.019 14.7 0.1 0.054 13.2 0.1 1.6 2 0 0 2 2 2 0 Peptidase family M13 ANAPC3 PF12895.7 PXF48779.1 - 0.031 14.5 1.3 24 5.2 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 PXF48779.1 - 0.059 12.8 1.7 14 5.0 0.0 3.8 5 0 0 5 5 5 0 Coatomer epsilon subunit Wzy_C_2 PF11846.8 PXF48779.1 - 0.084 12.8 5.6 16 5.3 0.0 4.3 5 0 0 5 5 4 0 Virulence factor membrane-bound polymerase, C-terminal FAT PF02259.23 PXF48779.1 - 0.1 11.8 2.1 1.7 7.8 0.1 3.6 3 1 0 4 4 4 0 FAT domain TPR_21 PF09976.9 PXF48779.1 - 0.31 10.7 11.1 3.1 7.5 0.3 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat-like domain PPR_1 PF12854.7 PXF48779.1 - 0.93 9.3 17.8 8.3 6.2 0.4 7.8 10 0 0 10 10 9 0 PPR repeat VWA PF00092.28 PXF48780.1 - 1.2e-15 58.2 0.0 1.7e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PXF48780.1 - 6.7e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PXF48780.1 - 0.0047 16.9 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain 5_nucleotid_C PF02872.18 PXF48780.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain HAGH_C PF16123.5 PXF48781.1 - 4.8e-27 94.3 0.1 1e-26 93.3 0.1 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PXF48781.1 - 1.4e-09 38.2 0.8 0.0003 20.9 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily DDOST_48kD PF03345.14 PXF48781.1 - 0.016 14.0 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta NUDIX PF00293.28 PXF48781.1 - 0.047 13.7 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 NUDIX domain HEAT_2 PF13646.6 PXF48782.1 - 0.065 13.6 7.5 0.046 14.1 0.6 4.3 4 0 0 4 4 4 0 HEAT repeats DUF2379 PF09543.10 PXF48782.1 - 0.34 11.1 2.2 0.47 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) Ribosomal_L35Ae PF01247.18 PXF48783.1 - 2.7e-36 123.6 1.1 3e-36 123.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 PXF48783.1 - 4.5e-05 23.6 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 2 RimM N-terminal domain Ribosomal_S11 PF00411.19 PXF48784.1 - 8.4e-46 154.9 0.5 1e-45 154.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 PXF48784.1 - 0.036 13.8 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CBM_25 PF03423.13 PXF48784.1 - 0.037 14.3 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ribosomal_S17 PF00366.20 PXF48785.1 - 1.4e-26 92.4 0.3 1.8e-26 92.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 PXF48785.1 - 3.2e-25 88.3 0.1 6.9e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Rho_RNA_bind PF07497.12 PXF48785.1 - 0.036 13.9 0.1 0.076 12.9 0.0 1.5 1 1 0 1 1 1 0 Rho termination factor, RNA-binding domain PCB_OB PF17092.5 PXF48785.1 - 0.049 14.4 0.0 0.078 13.7 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain GTP_EFTU PF00009.27 PXF48786.1 - 7.5e-46 156.1 0.2 1.1e-45 155.5 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PXF48786.1 - 1.3e-18 67.3 0.1 5.3e-18 65.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PXF48786.1 - 1.2e-12 48.1 0.4 7e-12 45.6 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF48786.1 - 0.00039 20.5 0.1 0.0037 17.3 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 PXF48786.1 - 0.0067 16.3 0.4 0.12 12.3 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu domain 4 CBM53 PF16760.5 PXF48787.1 - 1e-05 26.0 2.0 0.0032 18.0 0.1 2.6 2 1 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CBM_25 PF03423.13 PXF48787.1 - 0.00017 21.8 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain (family 25) Lactamase_B_2 PF12706.7 PXF48788.1 - 6.1e-09 35.7 0.2 0.00039 20.0 0.2 2.7 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PXF48788.1 - 0.082 12.9 0.7 0.082 12.9 0.7 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily ClpS PF02617.17 PXF48789.1 - 5.9e-18 64.4 0.2 9e-18 63.9 0.2 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Imm44 PF15571.6 PXF48789.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 44 Glyco_tranf_2_2 PF10111.9 PXF48790.1 - 2.7e-08 33.6 0.0 0.00084 18.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PXF48790.1 - 2.2e-07 30.9 0.0 4.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 PXF48790.1 - 6.1e-07 29.0 0.1 1.4e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase XG_FTase PF03254.13 PXF48790.1 - 0.00036 19.3 0.0 0.66 8.5 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase O-FucT PF10250.9 PXF48790.1 - 0.00041 20.1 1.3 0.098 12.3 1.3 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 PXF48790.1 - 0.026 13.4 0.1 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) Glyco_tranf_2_4 PF13704.6 PXF48790.1 - 0.064 13.8 1.0 0.31 11.6 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 2 ATP-synt_Eps PF04627.13 PXF48790.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain YjeF_N PF03853.15 PXF48791.1 - 2.4e-21 76.4 0.0 4.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus CPBP PF02517.16 PXF48792.1 - 5.6e-14 52.3 0.1 5.6e-14 52.3 0.1 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Ion_trans PF00520.31 PXF48792.1 - 0.015 14.6 3.3 0.024 13.9 3.0 1.5 1 1 0 1 1 1 0 Ion transport protein Proteasome PF00227.26 PXF48793.1 - 3.3e-47 160.4 0.8 3.8e-47 160.2 0.8 1.0 1 0 0 1 1 1 1 Proteasome subunit MTHFR PF02219.17 PXF48794.1 - 1.6e-113 378.8 0.0 2.6e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TTc_toxin_rep PF18807.1 PXF48794.1 - 0.11 12.3 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Tripartite Tc toxins repeat DNA_pol_E_B PF04042.16 PXF48795.1 - 1.4e-33 116.0 0.0 1.9e-32 112.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 PXF48795.1 - 7.8e-24 84.2 0.0 1.6e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Myb_DNA-binding PF00249.31 PXF48796.1 - 1.5e-13 50.7 0.1 2.9e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF48796.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PXF48796.1 - 0.0057 16.9 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RskA PF10099.9 PXF48796.1 - 0.0067 16.7 6.9 0.0067 16.7 6.9 1.9 2 0 0 2 2 2 1 Anti-sigma-K factor rskA HR1 PF02185.16 PXF48796.1 - 0.32 11.1 0.0 0.32 11.1 0.0 2.4 3 0 0 3 3 3 0 Hr1 repeat Phage_r1t_holin PF16945.5 PXF48796.1 - 9.1 6.6 13.4 33 4.8 9.2 2.7 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin Lyase_1 PF00206.20 PXF48797.1 - 7e-27 94.6 0.0 1.3e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 PXF48797.1 - 5e-18 65.4 0.2 1.3e-17 64.1 0.2 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF2046 PF09755.9 PXF48798.1 - 1.2e-21 77.3 20.2 1.7e-21 76.8 20.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Phage_Mu_Gam PF07352.12 PXF48798.1 - 0.0027 17.6 3.9 0.0027 17.6 3.9 2.5 2 1 1 3 3 3 1 Bacteriophage Mu Gam like protein Deltaretro_Tax PF05599.11 PXF48798.1 - 0.024 15.2 0.7 0.042 14.4 0.7 1.4 1 0 0 1 1 1 0 Deltaretrovirus Tax protein HALZ PF02183.18 PXF48798.1 - 0.025 14.8 1.8 0.025 14.8 1.8 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper Prominin PF05478.11 PXF48798.1 - 0.029 12.4 12.8 0.037 12.0 12.8 1.0 1 0 0 1 1 1 0 Prominin Filament PF00038.21 PXF48798.1 - 0.065 12.8 26.3 0.43 10.1 24.3 1.9 1 1 1 2 2 2 0 Intermediate filament protein Ribonucleas_3_2 PF11469.8 PXF48798.1 - 0.39 11.2 2.9 0.65 10.4 0.6 2.2 1 1 2 3 3 3 0 Ribonuclease III Vac_Fusion PF02346.16 PXF48798.1 - 0.45 10.2 7.2 0.54 9.9 3.8 2.4 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 STN1_2 PF09170.10 PXF48798.1 - 0.52 10.5 7.9 0.68 10.1 7.9 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF572 PF04502.13 PXF48798.1 - 0.98 9.0 12.0 1.3 8.6 12.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4763 PF15960.5 PXF48798.1 - 1 8.6 25.9 0.94 8.7 11.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 PXF48798.1 - 1.6 7.6 27.6 0.79 8.6 14.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 PXF48798.1 - 2 7.2 12.7 2.5 6.9 12.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LCIB_C_CA PF18599.1 PXF48798.1 - 2.2 7.5 5.4 2.2 7.5 2.9 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases V_ATPase_I PF01496.19 PXF48798.1 - 2.2 6.1 11.3 2.9 5.7 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.11 PXF48798.1 - 2.4 7.6 14.4 0.17 11.3 1.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein FlgN PF05130.12 PXF48798.1 - 4.4 7.8 24.0 0.06 13.9 4.8 2.8 2 1 0 2 2 2 0 FlgN protein DUF4162 PF13732.6 PXF48798.1 - 4.7 8.0 8.7 1.2 9.9 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4162) DUF2730 PF10805.8 PXF48798.1 - 4.7 7.3 8.6 3.7 7.7 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) WDCP PF15390.6 PXF48798.1 - 6.2 5.1 13.7 7.3 4.8 13.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family zf-C2H2_assoc PF16606.5 PXF48798.1 - 8.5 6.7 9.4 0.92 9.8 3.0 2.5 2 2 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF1690 PF07956.11 PXF48798.1 - 9 6.7 27.0 5.5 7.4 7.1 2.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Brix PF04427.18 PXF48799.1 - 1.8e-38 132.6 0.2 3.4e-38 131.7 0.2 1.4 1 0 0 1 1 1 1 Brix domain CPSF100_C PF13299.6 PXF48799.1 - 0.17 12.0 7.6 6.3 6.9 4.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AP-5_subunit_s1 PF15001.6 PXF48799.1 - 0.34 10.9 5.2 0.7 9.9 5.2 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Arf PF00025.21 PXF48800.1 - 2.2e-76 255.2 0.0 2.6e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PXF48800.1 - 2.2e-14 53.4 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF48800.1 - 2.6e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PXF48800.1 - 5.9e-13 48.6 0.0 7.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PXF48800.1 - 4e-12 46.0 0.7 4.9e-08 32.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PXF48800.1 - 4.8e-10 39.2 0.0 6.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF48800.1 - 2.9e-05 24.1 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PXF48800.1 - 0.0057 16.0 0.4 0.016 14.5 0.4 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 PXF48800.1 - 0.073 12.7 0.0 0.59 9.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPK PF03770.16 PXF48801.1 - 3.4e-47 160.9 0.0 5.8e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF737 PF05300.11 PXF48801.1 - 0.12 12.7 4.1 0.49 10.7 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) UbiA PF01040.18 PXF48802.1 - 2.1e-47 161.5 18.9 2.8e-47 161.1 18.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family SID-1_RNA_chan PF13965.6 PXF48802.1 - 0.031 12.7 0.0 0.043 12.2 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDE_Tnp_1_6 PF13751.6 PXF48803.1 - 0.034 14.4 1.2 0.049 13.8 1.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain SRP19 PF01922.17 PXF48804.1 - 1e-28 100.1 0.1 1.7e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 SRP19 protein Peptidase_M50 PF02163.22 PXF48806.1 - 1.7e-05 24.2 4.0 5.2e-05 22.7 0.2 2.5 1 1 0 2 2 2 2 Peptidase family M50 TPT PF03151.16 PXF48807.1 - 4e-55 187.2 21.1 4.6e-55 187.0 21.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF48807.1 - 1.7e-18 67.1 31.0 1.7e-10 41.2 14.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PXF48807.1 - 5.2e-07 29.2 22.9 6.7e-07 28.8 22.9 1.1 1 0 0 1 1 1 1 UAA transporter family Holin_9 PF16936.5 PXF48807.1 - 0.81 9.9 9.4 0.61 10.3 5.9 2.4 2 0 0 2 2 2 0 Putative holin PDZ PF00595.24 PXF48808.1 - 2e-05 24.9 0.1 3.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Ribosomal_S21 PF01165.20 PXF48809.1 - 1.5e-17 63.0 2.8 2e-17 62.6 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 PPR_2 PF13041.6 PXF48810.1 - 7.3e-22 77.3 0.1 1.5e-10 41.1 0.1 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 PXF48810.1 - 4e-17 61.2 1.7 0.00017 21.6 0.1 6.7 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 PXF48810.1 - 8.1e-14 51.4 0.0 7.9e-08 32.3 0.0 4.5 4 1 1 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF48810.1 - 6.4e-11 42.0 0.0 7.7e-05 22.2 0.0 3.2 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PXF48810.1 - 3.6e-06 26.6 1.2 0.00021 20.9 0.0 3.4 4 0 0 4 4 4 1 PPR repeat ATP13 PF12921.7 PXF48810.1 - 0.00018 21.4 0.0 2.9 7.8 0.0 3.9 4 0 0 4 4 4 2 Mitochondrial ATPase expression Ribosomal_L27A PF00828.19 PXF48811.1 - 4.8e-23 82.2 0.2 6.4e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GreA_GreB_N PF03449.15 PXF48812.1 - 0.03 14.5 0.1 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF2935 PF11155.8 PXF48813.1 - 0.48 10.8 8.3 15 6.0 3.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Col_cuticle_N PF01484.17 PXF48813.1 - 2.6 8.2 4.8 13 5.9 2.2 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain PUF PF00806.19 PXF48814.1 - 1.9e-47 156.3 0.1 1.4e-06 27.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Trns_repr_metal PF02583.17 PXF48814.1 - 0.1 13.0 0.2 0.44 10.9 0.2 2.1 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Glyco_hydro_35 PF01301.19 PXF48816.1 - 3.1e-92 309.6 0.1 4e-92 309.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 PXF48816.1 - 0.00052 20.6 0.5 0.007 16.9 0.0 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DSPc PF00782.20 PXF48817.1 - 1.9e-07 31.0 0.0 4.3e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PXF48817.1 - 5.1e-07 29.9 0.0 1.9e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PXF48817.1 - 3.7e-06 27.1 0.0 6.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PXF48817.1 - 0.00044 19.9 0.1 0.00077 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 PXF48817.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 PXF48817.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 Putative phosphatase (DUF442) CDKN3 PF05706.12 PXF48817.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Branch PF02485.21 PXF48818.1 - 4.1e-34 118.2 1.1 6.1e-34 117.6 1.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Y_Y_Y PF07495.13 PXF48819.1 - 0.16 12.0 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Y_Y_Y domain FAD_binding_7 PF03441.14 PXF48820.1 - 2.4e-52 177.4 0.1 4e-52 176.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PXF48820.1 - 3.5e-29 101.9 0.4 1.5e-16 60.9 0.0 2.7 2 0 0 2 2 2 2 DNA photolyase Polyketide_cyc PF03364.20 PXF48822.1 - 9e-15 55.0 0.1 1.3e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PXF48822.1 - 5.1e-09 36.5 0.0 8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 PXF48822.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) SET PF00856.28 PXF48826.1 - 1.2e-17 64.8 3.0 6.5e-14 52.7 0.0 4.1 4 1 1 5 5 5 2 SET domain AWS PF17907.1 PXF48826.1 - 7.7e-08 32.2 4.9 1.6e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 AWS domain Nucleoporin2 PF04096.14 PXF48827.1 - 1.8e-29 102.8 0.0 2.8e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Tubulin PF00091.25 PXF48829.1 - 5e-70 235.7 0.0 2e-69 233.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PXF48829.1 - 4e-43 146.6 0.0 9.8e-43 145.3 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PXF48829.1 - 1.7e-05 25.1 0.1 9.5e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PXF48829.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Arf PF00025.21 PXF48830.1 - 2.2e-66 222.6 0.1 2.6e-66 222.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PXF48830.1 - 9.7e-14 51.6 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF48830.1 - 7.9e-12 45.1 0.0 8.9e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PXF48830.1 - 1.3e-10 41.0 0.1 1.7e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PXF48830.1 - 2.3e-08 33.6 0.9 1.1e-05 24.8 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PXF48830.1 - 3.7e-08 33.0 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PXF48830.1 - 0.0002 21.4 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 PXF48830.1 - 0.00055 19.0 0.5 0.007 15.4 0.0 2.4 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 PXF48830.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 PXF48830.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain SF3A2 PF16835.5 PXF48831.1 - 2.1e-36 124.1 0.0 3.9e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 PXF48831.1 - 6.5e-06 26.4 0.5 1.3e-05 25.4 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 PXF48831.1 - 0.00035 20.5 0.1 0.00054 19.9 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1772 PF08592.11 PXF48832.1 - 4.3e-17 62.7 1.3 5.6e-17 62.3 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MrpF_PhaF PF04066.13 PXF48832.1 - 0.08 13.4 0.8 0.08 13.4 0.8 2.2 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2057 PF09829.9 PXF48834.1 - 0.0099 16.1 0.2 0.014 15.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) Adaptin_N PF01602.20 PXF48835.1 - 7.5e-103 344.9 3.2 1e-102 344.4 3.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PXF48835.1 - 2.1e-16 60.4 0.1 4e-14 53.0 0.0 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PXF48835.1 - 1.4e-06 28.6 16.8 0.0092 16.4 0.4 5.3 3 1 2 5 5 5 2 HEAT repeats AP3B1_C PF14796.6 PXF48835.1 - 8.4e-05 22.9 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_EZ PF13513.6 PXF48835.1 - 0.21 12.1 12.9 0.37 11.3 0.1 5.4 4 2 2 6 6 6 0 HEAT-like repeat HEAT PF02985.22 PXF48835.1 - 7.7 7.1 14.3 1.1 9.7 0.2 5.4 7 0 0 7 7 7 0 HEAT repeat SID-1_RNA_chan PF13965.6 PXF48836.1 - 0.034 12.6 0.0 0.054 11.9 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SID-1_RNA_chan PF13965.6 PXF48837.1 - 0.034 12.6 0.0 0.054 11.9 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIF2 PF04631.12 PXF48838.1 - 0.048 12.5 0.1 0.084 11.7 0.1 1.3 1 0 0 1 1 1 0 Per os infectivity factor 2 UQ_con PF00179.26 PXF48840.1 - 4.5e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2457 PF10446.9 PXF48840.1 - 2 7.5 10.7 0.14 11.3 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TRAM_LAG1_CLN8 PF03798.16 PXF48841.1 - 4.6e-11 42.8 7.1 4.7e-10 39.5 7.8 2.0 1 1 1 2 2 2 2 TLC domain bZIP_1 PF00170.21 PXF48843.1 - 0.0087 16.1 11.5 0.017 15.2 11.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor HTH_WhiA PF02650.14 PXF48843.1 - 0.061 13.7 0.5 12 6.3 0.0 2.5 2 0 0 2 2 2 0 WhiA C-terminal HTH domain TFIIS_C PF01096.18 PXF48844.1 - 8.7e-15 54.3 0.3 8.7e-15 54.3 0.3 2.5 3 0 0 3 3 2 1 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.12 PXF48844.1 - 0.00037 20.4 1.0 0.00037 20.4 1.0 2.6 3 1 0 3 3 3 1 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.6 PXF48844.1 - 0.00084 19.0 8.0 0.91 9.3 0.1 4.1 4 0 0 4 4 4 2 zinc-ribbon domain Lar_restr_allev PF14354.6 PXF48844.1 - 0.0011 19.3 3.0 0.69 10.3 0.1 2.3 2 0 0 2 2 2 2 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 PXF48844.1 - 0.0021 18.2 10.2 0.69 10.1 0.1 3.5 3 0 0 3 3 3 2 Zinc ribbon domain Hen1_L PF12623.7 PXF48844.1 - 0.0029 16.7 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 RNA repair, ligase-Pnkp-associating, region of Hen1 Zn_Tnp_IS91 PF14319.6 PXF48844.1 - 0.0071 16.4 3.6 1.6 8.8 0.2 2.3 2 0 0 2 2 2 2 Transposase zinc-binding domain TMF_TATA_bd PF12325.8 PXF48844.1 - 0.0088 16.3 0.7 0.011 15.9 0.7 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Zn_Tnp_IS1595 PF12760.7 PXF48844.1 - 0.038 14.0 6.7 0.13 12.3 0.4 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 PXF48844.1 - 0.038 13.7 6.0 1.7 8.5 2.6 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 Peptidase_C27 PF05407.12 PXF48844.1 - 0.057 13.5 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 Rubella virus endopeptidase zf-ribbon_3 PF13248.6 PXF48844.1 - 0.17 11.4 13.0 0.57 9.7 0.2 4.2 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 PXF48844.1 - 0.23 11.5 6.7 0.07 13.2 3.1 2.1 2 1 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PXF48844.1 - 0.46 10.6 10.0 42 4.3 10.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon DUF3268 PF11672.8 PXF48844.1 - 0.78 10.1 4.8 0.7 10.2 0.2 2.4 2 1 0 2 2 2 0 zinc-finger-containing domain UPF0547 PF10571.9 PXF48844.1 - 1 9.5 14.3 3.7 7.7 0.2 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DNA_RNApol_7kD PF03604.13 PXF48844.1 - 1.3 8.7 8.5 11 5.8 1.3 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.12 PXF48844.1 - 1.4 8.5 9.9 5.8 6.5 0.1 3.7 2 2 1 3 3 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 PXF48844.1 - 2.1 8.4 12.1 13 5.8 0.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 PXF48844.1 - 2.4 8.2 9.0 1.1 9.3 1.8 2.6 2 2 1 3 3 3 0 zinc-ribbons OrfB_Zn_ribbon PF07282.11 PXF48844.1 - 5 7.1 8.8 6 6.9 0.8 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.10 PXF48844.1 - 6.4 6.6 13.4 6.5 6.6 0.3 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain Malectin PF11721.8 PXF48845.1 - 7.5e-18 65.2 0.0 9.9e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Malectin domain zf-H3C2 PF16721.5 PXF48846.1 - 0.039 14.3 0.8 0.62 10.5 1.2 2.4 2 1 0 2 2 2 0 Zinc-finger like, probable DNA-binding Glyco_transf_20 PF00982.21 PXF48847.1 - 1.1e-146 489.3 0.0 1.4e-146 488.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PXF48847.1 - 7.5e-56 188.9 0.0 1.2e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 PXF48847.1 - 1.6e-13 50.3 0.0 5.2e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Starch binding domain Hydrolase_3 PF08282.12 PXF48847.1 - 0.00052 19.8 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GTP_EFTU PF00009.27 PXF48848.1 - 2.7e-62 209.8 0.0 3.7e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PXF48848.1 - 5.2e-29 100.5 0.0 1.2e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 PXF48848.1 - 8.8e-22 77.0 0.0 2.8e-21 75.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 PXF48848.1 - 7e-15 54.9 0.0 1.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PXF48848.1 - 2.4e-13 50.3 0.3 5.2e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF48848.1 - 0.0051 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Calreticulin PF00262.18 PXF48849.1 - 5.8e-138 459.7 5.8 9.2e-138 459.1 5.8 1.3 1 0 0 1 1 1 1 Calreticulin family TRAP_alpha PF03896.16 PXF48849.1 - 0.046 12.9 0.4 0.046 12.9 0.4 2.6 4 0 0 4 4 4 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 PXF48850.1 - 3.4e-70 236.4 0.0 4.3e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48850.1 - 1e-38 133.1 0.0 1.4e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF48850.1 - 5.7e-05 22.1 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 PXF48850.1 - 0.00065 20.2 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 PXF48850.1 - 0.0026 16.7 0.4 0.0026 16.7 0.4 1.7 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PXF48850.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 PXF48850.1 - 0.053 13.4 0.1 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_8 PF15409.6 PXF48850.1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain RIO1 PF01163.22 PXF48850.1 - 0.12 11.9 0.5 0.21 11.2 0.5 1.3 1 0 0 1 1 1 0 RIO1 family GNT-I PF03071.15 PXF48851.1 - 2.6e-33 115.5 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 PXF48851.1 - 1e-05 24.8 0.0 0.00081 18.6 0.0 2.1 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Glyco_tranf_2_3 PF13641.6 PXF48851.1 - 8e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_18 PF15024.6 PXF48851.1 - 0.0015 17.3 1.4 0.002 16.8 1.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_transf_25 PF01755.17 PXF48851.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF676 PF05057.14 PXF48853.1 - 1.7e-27 96.4 0.1 2.6e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PXF48853.1 - 0.00023 21.1 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PXF48853.1 - 0.0011 18.6 0.5 0.0033 17.1 0.1 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PXF48853.1 - 0.0081 16.0 0.1 0.061 13.1 0.1 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase NeA_P2 PF12312.8 PXF48853.1 - 0.032 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Pkinase PF00069.25 PXF48854.1 - 1.2e-54 185.5 0.0 1.6e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48854.1 - 2.1e-27 96.1 0.0 4.4e-27 95.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF48854.1 - 0.0003 19.7 0.0 0.0003 19.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PXF48854.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF48854.1 - 0.09 12.1 0.5 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Mem_trans PF03547.18 PXF48855.1 - 1.7 7.0 3.6 3 6.1 3.6 1.4 1 0 0 1 1 1 0 Membrane transport protein HSP20 PF00011.21 PXF48856.1 - 6.8e-14 51.9 0.1 7.9e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF48856.1 - 1.6e-06 27.6 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 PXF48856.1 - 0.043 14.8 0.0 0.067 14.2 0.0 1.3 1 0 0 1 1 1 0 CS domain FecCD PF01032.18 PXF48857.1 - 0.12 11.3 4.6 0.33 9.9 4.8 1.5 2 0 0 2 2 2 0 FecCD transport family HSP20 PF00011.21 PXF48858.1 - 7.5e-11 42.1 0.5 5.5e-10 39.3 0.5 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF48858.1 - 1.8e-05 24.2 0.0 7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 PXF48858.1 - 0.0027 18.1 0.0 0.0056 17.1 0.0 1.6 1 1 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 PXF48858.1 - 0.057 14.4 0.1 0.1 13.6 0.0 1.5 1 1 0 1 1 1 0 CS domain MATH PF00917.26 PXF48859.1 - 0.00058 20.0 0.0 0.0083 16.3 0.0 2.2 2 0 0 2 2 2 1 MATH domain HSP20 PF00011.21 PXF48860.1 - 6e-09 36.0 0.3 3.6e-08 33.5 0.3 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF48860.1 - 9.4e-07 28.3 0.0 2.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 PXF48860.1 - 0.049 14.0 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 PIH1 CS-like domain HSP20 PF00011.21 PXF48861.1 - 5e-13 49.1 0.7 2.6e-12 46.8 0.7 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PXF48861.1 - 2.7e-06 26.8 0.0 3.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 PXF48861.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 PIH1 CS-like domain CPSase_L_D2 PF02786.17 PXF48862.1 - 1.2e-113 377.9 0.1 1.5e-80 269.7 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 PXF48862.1 - 8.2e-48 162.2 0.0 1.9e-47 161.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 PXF48862.1 - 1.1e-45 154.6 0.0 2.8e-45 153.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.19 PXF48862.1 - 5.8e-40 136.4 0.0 1.4e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 PXF48862.1 - 1.1e-39 136.2 0.0 2.3e-39 135.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace PF00185.24 PXF48862.1 - 1.1e-33 116.5 0.0 2e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 PXF48862.1 - 7e-18 64.6 0.0 2.5e-17 62.8 0.0 2.0 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 PXF48862.1 - 1.3e-17 64.0 0.3 1.5e-09 37.7 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PXF48862.1 - 5.4e-15 55.4 0.1 3e-08 33.4 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 PXF48862.1 - 3.9e-13 49.3 0.3 7.4e-08 32.2 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PXF48862.1 - 2.7e-07 30.8 0.2 0.00037 20.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 PXF48862.1 - 0.00011 22.0 0.7 0.0038 17.0 0.7 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 PXF48862.1 - 0.0003 20.7 0.0 0.92 9.3 0.0 3.9 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 PXF48862.1 - 0.089 13.1 0.0 11 6.3 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Peptidase_M17_N PF02789.17 PXF48862.1 - 0.15 11.9 0.1 9.5 6.1 0.0 3.2 4 0 0 4 4 4 0 Cytosol aminopeptidase family, N-terminal domain RRM_1 PF00076.22 PXF48863.1 - 1.4e-35 120.9 0.0 1.9e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF48863.1 - 4.8e-11 42.6 0.0 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PXF48863.1 - 0.00029 20.8 0.1 0.31 11.1 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 PXF48863.1 - 0.041 14.1 0.0 1.9 8.7 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 PXF48863.1 - 0.093 12.4 0.6 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Frag1 PF10277.9 PXF48864.1 - 1.1e-07 31.6 4.9 1.5e-07 31.2 4.9 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family ABC_membrane_2 PF06472.15 PXF48865.1 - 1.4e-88 296.8 0.5 1.8e-88 296.4 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF48865.1 - 4.2e-18 66.2 0.0 1.3e-17 64.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PXF48865.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 PXF48865.1 - 0.022 14.5 1.8 0.14 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PXF48865.1 - 0.089 12.6 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PXF48865.1 - 0.19 12.2 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PXF48865.1 - 0.21 11.0 0.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain UCH PF00443.29 PXF48866.1 - 5.4e-45 153.9 0.2 1e-44 153.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 PXF48866.1 - 4.2e-30 104.8 0.0 5.9e-28 97.8 0.0 3.0 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 PXF48866.1 - 5.1e-24 85.1 0.1 6.8e-22 78.2 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 PXF48866.1 - 6.5e-20 72.0 0.3 3.4e-19 69.6 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 PXF48866.1 - 0.0092 16.1 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 MATH domain WD40 PF00400.32 PXF48867.1 - 6.7e-56 185.0 20.6 2.2e-10 40.9 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 PXF48867.1 - 7e-15 55.1 4.2 1.4e-14 54.1 4.2 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 PXF48867.1 - 7.4e-15 55.0 0.2 0.0073 16.6 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PXF48867.1 - 2e-10 40.5 0.0 0.0056 16.0 0.0 3.9 5 0 0 5 5 5 3 WD40-like domain Nup160 PF11715.8 PXF48867.1 - 5.1e-06 25.4 1.2 0.06 12.0 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PXF48867.1 - 0.0001 21.0 0.2 0.32 9.5 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 PXF48867.1 - 0.00018 21.4 0.0 0.24 11.3 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PXF48867.1 - 0.00047 19.2 0.0 2.6 6.9 0.0 3.9 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PXF48867.1 - 0.0019 18.0 0.1 5.5 7.1 0.0 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 PXF48867.1 - 0.0055 15.5 0.2 1.6 7.4 0.0 3.3 1 1 2 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 PXF48867.1 - 0.083 12.2 0.1 3 7.1 0.0 2.7 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 PXF48867.1 - 0.11 10.8 0.0 5.2 5.2 0.0 3.0 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1378 PF07125.11 PXF48867.1 - 0.11 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) DUF2076 PF09849.9 PXF48867.1 - 0.66 10.0 15.9 2 8.4 15.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rox3 PF08633.10 PXF48867.1 - 0.86 9.8 7.0 1.2 9.3 6.3 1.6 2 0 0 2 2 1 0 Rox3 mediator complex subunit DUF4175 PF13779.6 PXF48867.1 - 0.91 7.4 18.5 1.2 6.9 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HeLo PF14479.6 PXF48867.1 - 1.2 9.0 4.1 1.8 8.3 4.1 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation Spt20 PF12090.8 PXF48867.1 - 1.7 8.2 18.3 2.8 7.5 18.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF2347 PF09804.9 PXF48867.1 - 2.3 7.7 5.3 3.8 7.0 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4580 PF15162.6 PXF48868.1 - 0.043 13.4 0.0 2.6e+02 1.1 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4580) DUF3248 PF11609.8 PXF48868.1 - 0.052 13.5 4.8 44 4.1 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3248) DUF3349 PF11829.8 PXF48868.1 - 0.24 12.2 2.2 2.2e+02 2.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3349) YokU PF14122.6 PXF48869.1 - 0.1 12.6 0.3 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin DUF1768 PF08719.11 PXF48870.1 - 2.2e-50 171.1 0.0 2.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Mito_carr PF00153.27 PXF48871.1 - 3.1e-12 46.2 6.2 0.00017 21.5 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein NHL PF01436.21 PXF48872.1 - 4.6e-29 99.0 0.1 5.1e-06 26.3 0.4 6.8 6 0 0 6 6 6 6 NHL repeat Thioredoxin_8 PF13905.6 PXF48872.1 - 5.5e-13 49.1 0.0 1.5e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like SGL PF08450.12 PXF48872.1 - 2.8e-07 30.4 0.1 0.058 13.0 0.0 3.7 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Redoxin PF08534.10 PXF48872.1 - 6.9e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 PXF48872.1 - 0.0011 19.0 0.0 0.019 15.0 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin Arylesterase PF01731.20 PXF48872.1 - 0.033 14.4 0.0 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 Arylesterase FKBP_C PF00254.28 PXF48873.1 - 1.5e-23 82.9 0.0 2.9e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 PXF48873.1 - 1e-05 26.0 0.1 2.8e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Nucleoplasmin-like domain Nop14 PF04147.12 PXF48873.1 - 0.23 9.6 3.4 0.26 9.5 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PXF48873.1 - 1.4 6.9 8.6 2.2 6.3 8.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 PXF48873.1 - 1.6 8.0 7.0 2.2 7.5 7.0 1.1 1 0 0 1 1 1 0 BUD22 Thioredoxin PF00085.20 PXF48874.1 - 5.2e-38 129.2 0.1 1.4e-26 92.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 PXF48874.1 - 6.8e-17 62.2 1.0 1.6e-16 61.0 1.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 PXF48874.1 - 4.4e-09 36.1 0.1 1.1e-05 25.0 0.0 2.5 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PXF48874.1 - 1.1e-06 29.0 0.1 0.00017 22.0 0.1 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PXF48874.1 - 0.0012 19.1 0.0 0.084 13.2 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 PXF48874.1 - 0.0016 18.6 0.0 0.0062 16.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF48874.1 - 0.0021 17.9 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.6 PXF48874.1 - 0.0025 17.7 0.9 0.0025 17.7 0.9 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 PXF48874.1 - 0.0035 17.2 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Calsequestrin PF01216.17 PXF48874.1 - 0.0084 15.2 0.2 0.015 14.4 0.2 1.3 1 0 0 1 1 1 1 Calsequestrin HyaE PF07449.11 PXF48874.1 - 0.016 15.2 0.0 0.83 9.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Ykof PF07615.11 PXF48874.1 - 0.038 14.5 0.0 7.6 7.1 0.0 2.4 2 0 0 2 2 2 0 YKOF-related Family YqcI_YcgG PF08892.11 PXF48874.1 - 0.15 11.9 1.4 0.29 10.9 0.1 2.1 2 1 0 2 2 2 0 YqcI/YcgG family Thioredoxin_4 PF13462.6 PXF48874.1 - 0.44 10.7 2.5 6.2 7.0 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin ADH_N PF08240.12 PXF48875.1 - 7.7e-30 103.0 0.4 1.8e-29 101.8 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PXF48875.1 - 4.6e-22 78.4 0.4 1.1e-21 77.1 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PXF48875.1 - 3.9e-08 33.0 1.0 1.7e-07 30.9 1.0 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PXF48875.1 - 0.015 16.4 0.0 0.027 15.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PXF48875.1 - 0.016 14.5 0.8 0.032 13.5 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PXF48875.1 - 0.26 9.9 0.2 0.38 9.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Claudin_2 PF13903.6 PXF48876.1 - 2.4e-11 43.8 9.9 5.5e-11 42.6 9.9 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 PXF48876.1 - 1.9e-10 40.9 4.1 1.3e-05 25.1 5.7 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 PXF48876.1 - 0.0022 18.3 5.7 0.041 14.1 2.3 2.9 2 1 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein DUF805 PF05656.14 PXF48876.1 - 0.011 16.1 2.5 0.014 15.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF872 PF05915.12 PXF48876.1 - 0.027 14.6 1.1 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Tom22 PF04281.13 PXF48876.1 - 0.29 10.9 2.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF2157 PF09925.9 PXF48876.1 - 0.47 10.2 9.2 1.2 8.9 7.2 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PRA1 PF03208.19 PXF48876.1 - 3.4 7.3 10.4 15 5.2 7.2 2.9 2 1 0 2 2 2 0 PRA1 family protein DUF4231 PF14015.6 PXF48876.1 - 8.4 6.9 8.6 1.6 9.3 3.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) FTO_CTD PF12934.7 PXF48878.1 - 0.29 10.9 1.6 1.3 8.7 1.5 2.2 2 0 0 2 2 2 0 FTO C-terminal domain WD40 PF00400.32 PXF48879.1 - 1.7e-45 152.0 31.8 5e-09 36.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF48879.1 - 4.2e-09 36.6 2.6 0.37 11.1 0.0 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PXF48879.1 - 0.0038 15.8 0.1 0.87 8.1 0.2 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 PXF48879.1 - 0.0043 15.7 14.5 0.06 12.0 0.2 5.4 2 2 3 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 PXF48879.1 - 0.032 13.6 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 PXF48879.1 - 0.1 12.6 0.1 14 5.7 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat FGGY_N PF00370.21 PXF48880.1 - 2.8e-69 233.4 0.4 3.9e-69 232.9 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PXF48880.1 - 4.6e-60 202.7 0.2 4.6e-59 199.5 0.1 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain OST3_OST6 PF04756.13 PXF48881.1 - 5.1e-48 163.9 0.9 6.6e-48 163.6 0.9 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family EVC2_like PF12297.8 PXF48881.1 - 0.34 9.5 0.4 0.51 9.0 0.4 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Voldacs PF03517.13 PXF48882.1 - 1.2e-07 31.9 0.5 0.0016 18.6 0.1 2.2 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling PH_TFIIH PF08567.11 PXF48882.1 - 0.033 14.5 0.4 0.055 13.8 0.4 1.3 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Inhibitor_I10 PF12559.8 PXF48883.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Serine endopeptidase inhibitors Methyltransf_11 PF08241.12 PXF48884.1 - 9e-19 67.9 0.0 2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF48884.1 - 7.2e-18 65.1 0.1 2.4e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF48884.1 - 9e-13 48.1 0.0 2.2e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF48884.1 - 1e-10 41.6 0.0 3.2e-10 40.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF48884.1 - 1e-08 35.8 0.0 2.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF48884.1 - 3.1e-06 27.1 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 PXF48884.1 - 0.0081 14.8 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 PXF48884.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 PXF48884.1 - 0.097 12.7 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PP2C PF00481.21 PXF48885.1 - 7.9e-61 205.9 0.0 1.1e-60 205.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 PXF48885.1 - 4.1e-40 137.8 0.0 6.8e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48885.1 - 3.9e-37 128.0 0.0 2.6e-36 125.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF48885.1 - 6.4e-09 35.1 0.1 1e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase PP2C_2 PF13672.6 PXF48885.1 - 2e-06 27.6 0.2 4.4e-06 26.5 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Kdo PF06293.14 PXF48885.1 - 0.0018 17.7 0.5 0.0034 16.8 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIE PF07228.12 PXF48885.1 - 0.0096 15.9 0.1 0.092 12.6 0.1 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 PXF48885.1 - 0.056 12.8 0.1 0.092 12.0 0.1 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PXF48885.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family LIM PF00412.22 PXF48886.1 - 1.9e-21 76.0 15.0 5e-11 42.7 3.1 2.4 2 0 0 2 2 2 2 LIM domain GREB1 PF15782.5 PXF48886.1 - 9.1 3.3 11.7 12 2.9 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sugar_tr PF00083.24 PXF48887.1 - 7.4e-74 249.2 24.6 7.9e-38 130.5 7.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PXF48887.1 - 5.7e-28 97.8 34.4 5.7e-28 97.8 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PXF48887.1 - 1.4e-10 41.0 7.0 1.4e-10 41.0 7.0 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1774 PF08611.10 PXF48887.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.8 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) MFS_1_like PF12832.7 PXF48887.1 - 2 7.2 16.3 0.55 9.0 2.3 2.6 1 1 1 2 2 2 0 MFS_1 like family SNF2_N PF00176.23 PXF48888.1 - 3e-62 210.4 1.3 1.4e-61 208.2 1.3 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF48888.1 - 8.7e-20 71.1 0.1 1.9e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF48888.1 - 0.00023 21.2 0.0 0.00062 19.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 PXF48888.1 - 1.8 8.6 17.0 3.7 7.6 17.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zinc-ribbons_6 PF07191.12 PXF48888.1 - 3.4 7.7 8.7 6.9 6.7 8.7 1.4 1 0 0 1 1 1 0 zinc-ribbons IBR PF01485.21 PXF48888.1 - 7.7 6.8 11.9 24 5.2 11.9 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain NUDIX PF00293.28 PXF48889.1 - 2.3e-17 63.2 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Polyketide_cyc PF03364.20 PXF48890.1 - 3e-14 53.3 0.1 3.6e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PXF48890.1 - 1.5e-13 51.2 0.2 2e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 PXF48890.1 - 0.046 14.0 0.1 0.059 13.6 0.1 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein H_PPase PF03030.16 PXF48891.1 - 6.2e-36 124.3 40.4 2.2e-35 122.4 38.6 2.5 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase zf-C2H2 PF00096.26 PXF48892.1 - 9.4e-10 38.4 31.1 3.3e-05 24.1 2.2 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF48892.1 - 1.3e-09 38.0 30.3 1.2e-05 25.4 2.2 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 PXF48892.1 - 1e-07 32.1 31.8 0.0015 19.2 1.0 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF48892.1 - 2.7e-05 24.3 15.6 0.022 15.0 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 PXF48892.1 - 0.0033 17.2 0.8 0.0033 17.2 0.8 5.1 5 0 0 5 5 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 PXF48892.1 - 0.0046 16.9 1.8 0.0046 16.9 1.8 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PXF48892.1 - 0.11 12.2 17.2 1.1 9.1 0.2 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 PXF48892.1 - 0.12 12.7 13.2 2 8.8 3.4 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 PXF48892.1 - 0.22 12.0 18.9 0.41 11.1 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF2321 PF10083.9 PXF48892.1 - 0.28 10.8 4.0 0.14 11.8 0.8 1.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Actin_micro PF17003.5 PXF48892.1 - 0.31 10.2 10.6 8.3 5.5 9.2 2.7 1 1 0 1 1 1 0 Putative actin-like family HypA PF01155.19 PXF48892.1 - 1.1 9.3 6.9 56 3.8 6.9 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rep_fac-A_C PF08646.10 PXF48892.1 - 1.7 8.4 4.3 2.5 7.8 0.2 2.5 2 1 1 3 3 3 0 Replication factor-A C terminal domain zf-MYST PF17772.1 PXF48892.1 - 2.7 7.7 4.9 6 6.6 0.1 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf-AN1 PF01428.16 PXF48892.1 - 3.9 7.7 13.5 5.7 7.2 0.1 4.1 4 0 0 4 4 4 0 AN1-like Zinc finger HLH PF00010.26 PXF48893.1 - 9.8e-06 25.4 0.5 1.6e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4688 PF15752.5 PXF48894.1 - 0.19 10.9 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) UCH PF00443.29 PXF48896.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Actin PF00022.19 PXF48898.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Actin DUF4874 PF16173.5 PXF48898.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) CHIP_TPR_N PF18391.1 PXF48899.1 - 0.37 11.6 2.1 8.9 7.2 0.0 2.5 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain ING PF12998.7 PXF48900.1 - 2e-11 44.3 1.0 3.1e-11 43.7 1.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 PXF48900.1 - 3.5e-06 26.8 8.7 5.6e-06 26.1 8.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 PXF48900.1 - 0.0077 16.4 0.6 0.016 15.4 0.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain DUF2203 PF09969.9 PXF48900.1 - 0.012 16.3 1.0 0.032 14.9 1.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4551 PF15087.6 PXF48900.1 - 0.017 14.0 1.9 0.021 13.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-HC5HC2H PF13771.6 PXF48900.1 - 0.04 14.2 4.1 0.091 13.0 3.9 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Prefoldin PF02996.17 PXF48900.1 - 0.2 11.6 1.2 3.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIVA PF05103.13 PXF48900.1 - 8.8 6.4 9.2 0.59 10.2 3.8 1.8 2 1 0 2 2 2 0 DivIVA protein Thymidylate_kin PF02223.17 PXF48901.1 - 2.1e-38 131.9 0.0 2.4e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 PXF48901.1 - 2.4e-05 23.9 0.0 0.0051 16.3 0.0 2.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 PXF48901.1 - 0.0003 21.1 0.4 0.00074 19.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain UPF0270 PF06794.12 PXF48901.1 - 0.0025 17.9 0.2 2.7 8.1 0.1 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0270) dNK PF01712.19 PXF48901.1 - 0.004 17.0 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_33 PF13671.6 PXF48901.1 - 0.0069 16.6 0.2 0.029 14.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 PXF48901.1 - 0.058 13.2 0.1 0.45 10.4 0.0 2.1 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 PXF48901.1 - 0.1 13.1 0.0 0.44 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain NTP_transf_2 PF01909.23 PXF48902.1 - 8.9e-06 25.9 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 PXF48902.1 - 1.9e-05 24.7 0.1 0.0002 21.5 0.0 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 PXF48902.1 - 0.03 14.4 0.1 0.16 12.1 0.0 2.2 2 1 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase DUF4218 PF13960.6 PXF48905.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4218) DDE_1 PF03184.19 PXF48906.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease bZIP_1 PF00170.21 PXF48907.1 - 5e-06 26.5 6.0 5e-06 26.5 6.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF48907.1 - 0.002 18.1 10.2 0.002 18.1 10.2 2.1 2 0 0 2 2 2 1 Basic region leucine zipper NAD_binding_8 PF13450.6 PXF48908.1 - 1.1e-05 25.6 0.1 2.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF48908.1 - 0.0038 16.8 0.0 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF48908.1 - 0.14 11.4 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase H_PPase PF03030.16 PXF48909.1 - 2.8e-50 171.7 25.1 2.8e-50 171.7 25.1 2.6 2 1 0 2 2 2 1 Inorganic H+ pyrophosphatase Shisa PF13908.6 PXF48909.1 - 0.25 11.6 1.0 41 4.4 0.1 3.4 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator Ribosomal_L22 PF00237.19 PXF48911.1 - 9.9e-19 67.5 0.2 1.8e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Actin PF00022.19 PXF48912.1 - 2.1e-102 342.8 0.0 2.4e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PXF48912.1 - 0.14 11.0 0.0 2.3 7.0 0.0 2.5 3 0 0 3 3 3 0 MreB/Mbl protein Arf PF00025.21 PXF48913.1 - 3.6e-46 156.8 0.1 4.7e-46 156.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PXF48913.1 - 1.7e-18 66.7 0.0 2.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF48913.1 - 8.5e-16 58.3 0.0 1.6e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PXF48913.1 - 3.1e-09 36.4 0.2 2.3e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PXF48913.1 - 3.6e-09 36.3 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PXF48913.1 - 5.7e-08 32.8 0.0 1.9e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PXF48913.1 - 2.3e-07 30.4 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PXF48913.1 - 6.7e-05 22.5 0.2 0.005 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PXF48913.1 - 0.016 15.7 0.0 0.093 13.2 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 PXF48914.1 - 1.5e-37 129.0 0.0 2.3e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF48914.1 - 3.9e-09 36.2 0.1 8.6e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PXF48914.1 - 1.3e-06 28.9 0.4 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PXF48914.1 - 1.5e-06 28.1 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF48914.1 - 1.8e-06 28.2 0.6 0.0025 18.1 0.1 3.6 2 1 2 4 4 4 1 AAA domain AAA_5 PF07728.14 PXF48914.1 - 2e-06 27.8 0.1 9.7e-06 25.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PXF48914.1 - 6e-05 22.4 0.0 9.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PXF48914.1 - 0.0001 22.9 0.0 0.0003 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 PXF48914.1 - 0.0001 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PXF48914.1 - 0.00012 22.2 0.1 0.00083 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PXF48914.1 - 0.00021 21.3 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PXF48914.1 - 0.00034 20.4 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 PXF48914.1 - 0.00038 20.2 0.0 0.0013 18.5 0.0 1.9 2 1 0 2 2 1 1 AAA domain TniB PF05621.11 PXF48914.1 - 0.00053 19.5 0.0 0.78 9.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 PXF48914.1 - 0.0011 18.4 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PXF48914.1 - 0.0018 18.2 0.2 0.076 12.9 0.0 2.4 1 1 1 2 2 2 1 NACHT domain DUF815 PF05673.13 PXF48914.1 - 0.003 16.8 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PXF48914.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 PXF48914.1 - 0.0047 17.2 0.1 0.015 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 PXF48914.1 - 0.0057 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PXF48914.1 - 0.0063 16.3 0.0 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PXF48914.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 PXF48914.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Hydin_ADK PF17213.3 PXF48914.1 - 0.015 15.6 1.3 0.81 9.9 0.1 2.6 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain ATPase PF06745.13 PXF48914.1 - 0.018 14.4 0.1 0.91 8.8 0.1 2.2 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.12 PXF48914.1 - 0.019 14.3 0.0 0.045 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 PXF48914.1 - 0.021 14.4 1.0 0.1 12.2 0.1 2.3 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 PXF48914.1 - 0.024 14.5 0.0 0.083 12.8 0.0 1.7 1 1 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 PXF48914.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 PXF48914.1 - 0.029 14.3 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IPT PF01745.16 PXF48914.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase Sigma54_activat PF00158.26 PXF48914.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 PXF48914.1 - 0.068 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PXF48914.1 - 0.072 13.6 0.2 0.75 10.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 PXF48914.1 - 0.094 12.5 0.3 8 6.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 PXF48914.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 PXF48914.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PXF48914.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein FSAP_sig_propep PF03032.15 PXF48915.1 - 0.11 12.5 0.7 0.24 11.4 0.7 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide NUDIX PF00293.28 PXF48916.1 - 4.4e-10 39.7 0.0 8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Peptidase_M61_N PF17899.1 PXF48919.1 - 0.0062 16.6 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain Exonuc_V_gamma PF04257.14 PXF48920.1 - 0.07 11.3 0.4 0.078 11.2 0.4 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Sel1 PF08238.12 PXF48921.1 - 1.2e-10 41.7 0.1 1.1 10.0 0.0 7.1 8 0 0 8 8 8 3 Sel1 repeat TPR_19 PF14559.6 PXF48921.1 - 0.0071 16.8 13.2 1.8 9.2 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat 3H PF02829.14 PXF48925.1 - 0.14 12.5 1.0 0.45 10.8 1.0 1.8 1 1 0 1 1 1 0 3H domain PP2C PF00481.21 PXF48926.1 - 1.3e-42 146.2 0.0 1.9e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PXF48926.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) FHA PF00498.26 PXF48927.1 - 1.6e-10 41.1 0.0 2.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PXF48927.1 - 0.022 15.1 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Heme_oxygenase PF01126.20 PXF48928.1 - 1.5e-09 38.0 0.0 1.9e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase zf-RING_2 PF13639.6 PXF48929.1 - 5.3e-12 45.9 7.8 8.2e-12 45.3 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF48929.1 - 4.8e-10 39.0 3.2 4.8e-10 39.0 3.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PXF48929.1 - 1.3e-06 28.5 7.8 3e-06 27.4 7.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PXF48929.1 - 5.1e-06 26.4 3.4 5.1e-06 26.4 3.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PXF48929.1 - 7e-06 26.0 2.4 1.1e-05 25.4 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PXF48929.1 - 1.3e-05 24.9 5.8 2.3e-05 24.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF48929.1 - 0.00011 22.0 11.0 0.00024 20.9 10.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF48929.1 - 0.00018 21.4 4.1 0.00029 20.7 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF48929.1 - 0.00032 20.5 5.0 0.00047 20.0 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PXF48929.1 - 0.0014 18.5 3.5 0.0021 17.9 3.5 1.3 1 0 0 1 1 1 1 PHD-finger Endonuclease_7 PF02945.15 PXF48929.1 - 0.0046 16.8 0.3 0.0065 16.4 0.3 1.2 1 0 0 1 1 1 1 Recombination endonuclease VII Prok-RING_4 PF14447.6 PXF48929.1 - 0.016 15.0 6.6 0.03 14.2 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PXF48929.1 - 0.25 11.5 8.2 2.5 8.3 8.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PXF48929.1 - 0.47 10.1 8.1 0.89 9.2 7.2 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PXF48929.1 - 2 8.6 8.8 0.23 11.6 3.8 2.1 2 1 0 2 2 2 0 RING-variant domain Actin PF00022.19 PXF48930.1 - 0.0099 14.5 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Actin TPT PF03151.16 PXF48931.1 - 1.7e-15 57.2 15.3 2e-15 56.9 15.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PXF48931.1 - 1e-07 31.5 15.6 1.6e-07 30.8 15.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PXF48931.1 - 3.6e-06 27.2 27.8 0.0012 19.1 8.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 PXF48931.1 - 0.011 16.4 7.2 0.083 13.6 0.6 3.1 2 2 0 2 2 2 0 Small Multidrug Resistance protein DUF2721 PF11026.8 PXF48931.1 - 0.047 13.6 0.6 0.047 13.6 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) N6_N4_Mtase PF01555.18 PXF48935.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 DNA methylase E7 PF00527.18 PXF48936.1 - 0.015 15.5 3.2 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 E7 protein, Early protein GAGA_bind PF06217.12 PXF48936.1 - 0.12 12.6 4.5 0.16 12.2 4.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family HLH PF00010.26 PXF48937.1 - 0.00025 20.9 4.0 0.00066 19.6 4.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NICE-1 PF15845.5 PXF48937.1 - 0.36 11.6 0.1 0.36 11.6 0.1 1.7 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family DUF5423 PF17461.2 PXF48937.1 - 7.8 5.2 8.2 15 4.3 8.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Malic_M PF03949.15 PXF48940.1 - 4.2e-94 314.6 0.0 5.3e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PXF48940.1 - 6.3e-69 231.4 0.0 9.4e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pkinase PF00069.25 PXF48943.1 - 1.2e-64 218.3 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF48943.1 - 6.3e-31 107.6 0.0 9.2e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF48943.1 - 1.7e-08 33.8 0.1 2.6e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PXF48943.1 - 0.0038 16.6 0.0 0.023 14.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PXF48943.1 - 0.013 14.9 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zeta_toxin PF06414.12 PXF48943.1 - 0.024 13.9 2.6 0.056 12.7 1.8 1.9 2 0 0 2 2 2 0 Zeta toxin APH PF01636.23 PXF48943.1 - 0.069 13.1 8.2 0.077 12.9 0.1 3.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family Ipi1_N PF12333.8 PXF48943.1 - 0.15 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation ERG4_ERG24 PF01222.17 PXF48944.1 - 1.6e-66 224.8 15.8 2e-66 224.6 15.8 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 PXF48944.1 - 2.6e-05 23.9 2.2 7.1e-05 22.4 2.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Phage_holin_2_1 PF04971.12 PXF48944.1 - 0.021 14.8 1.5 0.12 12.4 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage P21 holin S Steroid_dh PF02544.16 PXF48944.1 - 0.031 14.3 0.1 0.031 14.3 0.1 3.1 4 1 1 5 5 5 0 3-oxo-5-alpha-steroid 4-dehydrogenase COX7B PF05392.11 PXF48944.1 - 0.74 9.5 3.1 0.37 10.5 0.4 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB FA_hydroxylase PF04116.13 PXF48945.1 - 1.9e-25 89.8 17.5 1.9e-25 89.8 17.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Bestrophin PF01062.21 PXF48946.1 - 6.8e-25 88.0 2.2 8.9e-25 87.7 2.2 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Trm56 PF01994.16 PXF48946.1 - 0.13 12.2 0.0 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 tRNA ribose 2'-O-methyltransferase, aTrm56 FAD-oxidase_C PF02913.19 PXF48947.1 - 7.3e-54 183.0 0.0 1.1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PXF48947.1 - 5.3e-34 116.9 3.1 1.7e-33 115.3 1.2 2.6 3 0 0 3 3 3 1 FAD binding domain tRNA-synt_2b PF00587.25 PXF48950.1 - 1.6e-43 148.8 0.0 3.3e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PXF48950.1 - 6.4e-15 55.1 0.2 1.9e-14 53.6 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 PXF48950.1 - 3.7e-13 49.3 0.0 9.1e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RelA_SpoT PF04607.17 PXF48951.1 - 8.4e-31 106.7 0.2 1.5e-30 105.9 0.2 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 PXF48951.1 - 2.9e-18 66.1 1.2 5.8e-18 65.1 1.2 1.5 1 0 0 1 1 1 1 HD domain TGS PF02824.21 PXF48951.1 - 0.00047 20.1 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 TGS domain Pro_CA PF00484.19 PXF48952.1 - 3.4e-39 134.6 1.7 4.7e-39 134.2 1.7 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Branch PF02485.21 PXF48953.1 - 2.9e-22 79.4 0.1 9.6e-22 77.7 0.1 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Ank_2 PF12796.7 PXF48954.1 - 5.9e-121 395.3 34.9 2.4e-16 60.1 0.0 10.7 3 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF48954.1 - 6.5e-78 256.2 27.6 3e-07 30.9 0.0 15.9 7 4 10 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 PXF48954.1 - 1.9e-77 252.5 43.0 4.7e-06 26.8 0.2 19.5 20 0 0 20 20 19 18 Ankyrin repeat Ank_3 PF13606.6 PXF48954.1 - 1.1e-74 237.4 24.3 0.00019 21.6 0.0 19.3 19 0 0 19 19 19 15 Ankyrin repeat Ank_5 PF13857.6 PXF48954.1 - 6.7e-70 230.3 38.4 1.2e-12 47.8 0.5 15.3 10 3 6 16 16 16 14 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 PXF48954.1 - 2.1e-11 44.0 4.0 5.2e-11 42.7 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PXF48954.1 - 2.1e-07 31.1 1.4 5.8e-07 29.7 1.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PXF48954.1 - 5.8e-07 29.1 2.0 5.8e-07 29.1 2.0 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF48954.1 - 3.8e-06 26.6 3.8 9.9e-06 25.3 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF48954.1 - 8.1e-06 25.6 2.2 2.4e-05 24.1 2.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF48954.1 - 5.8e-05 23.1 1.2 0.00026 21.0 1.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF48954.1 - 9.8e-05 22.2 2.5 9.8e-05 22.2 2.5 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF48954.1 - 0.00053 19.8 1.0 0.0012 18.7 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF48954.1 - 0.0013 18.4 2.1 0.0038 16.8 2.1 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PXF48954.1 - 0.0023 17.9 1.1 0.0084 16.1 1.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF48954.1 - 0.0068 16.3 2.7 0.016 15.0 2.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 VWA_3_C PF18571.1 PXF48954.1 - 0.075 12.9 0.6 78 3.3 0.1 4.2 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain FANCL_C PF11793.8 PXF48954.1 - 0.15 12.3 3.4 0.58 10.4 3.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 PXF48954.1 - 1.4 9.1 4.0 4.9 7.4 4.0 2.0 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 PXF48954.1 - 7.6 6.9 6.1 64 4.0 3.1 3.3 3 0 0 3 3 3 0 RING-like domain DUF5522 PF17653.1 PXF48955.1 - 1.1e-15 57.3 7.5 1.9e-15 56.5 7.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 PXF48955.1 - 7.1e-12 45.3 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Diphthamide synthase DUF4342 PF14242.6 PXF48956.1 - 3.6 7.6 6.7 2.4 8.2 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) RRM_1 PF00076.22 PXF48958.1 - 6.3e-17 61.2 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 PXF48958.1 - 2.2e-05 24.2 0.1 4.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain RRM_5 PF13893.6 PXF48958.1 - 0.0064 16.1 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF48958.1 - 0.18 11.9 0.0 0.51 10.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif GTP_EFTU PF00009.27 PXF48959.1 - 8.6e-60 201.6 0.2 1.1e-59 201.2 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PXF48959.1 - 1e-27 96.6 0.0 2.3e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PXF48959.1 - 9.7e-17 61.1 4.5 9.7e-17 61.1 3.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF48959.1 - 6.2e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF48959.1 - 0.0082 16.1 0.1 0.039 13.9 0.0 1.9 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 PXF48959.1 - 0.016 14.8 0.4 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 PXF48959.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Peptidase_C15 PF01470.17 PXF48960.1 - 2e-13 50.9 0.0 1.4e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 Pyroglutamyl peptidase PMT PF02366.18 PXF48963.1 - 3.3e-43 148.1 13.9 3.3e-43 148.1 13.9 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 PXF48963.1 - 6.4e-34 117.3 18.1 6.4e-34 117.3 18.1 2.4 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase VIT1 PF01988.19 PXF48963.1 - 5.5 6.8 6.5 3.1 7.6 3.4 2.1 2 0 0 2 2 2 0 VIT family NB-ARC PF00931.22 PXF48964.1 - 1.3e-16 60.6 0.0 2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 PXF48964.1 - 0.00067 20.1 0.9 0.0042 17.5 0.6 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PXF48964.1 - 0.0013 19.0 0.1 0.0065 16.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PXF48964.1 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PXF48964.1 - 0.011 15.3 0.1 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Pdase_C33_assoc PF14756.6 PXF48964.1 - 0.014 15.4 0.2 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 Peptidase_C33-associated domain FtsK_SpoIIIE PF01580.18 PXF48964.1 - 0.021 14.2 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 PXF48964.1 - 0.066 13.4 0.1 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF48964.1 - 0.1 12.5 0.7 0.34 10.8 0.7 1.9 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 PXF48964.1 - 0.73 10.2 2.5 0.76 10.1 0.6 2.1 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 PXF48965.1 - 0.0008 20.2 0.0 0.011 16.6 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat An_peroxidase PF03098.15 PXF48966.1 - 6.1e-117 391.4 0.1 6.7e-117 391.3 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase UPF0182 PF03699.13 PXF48968.1 - 2.2 6.3 5.8 2.7 6.0 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) GTP_EFTU PF00009.27 PXF48969.1 - 2e-49 167.8 0.0 2.9e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 PXF48969.1 - 2.4e-19 69.2 0.1 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PXF48969.1 - 2.9e-18 65.7 0.0 5.6e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 PXF48969.1 - 3e-08 33.5 0.0 5.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 PXF48969.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 PXF48969.1 - 0.0058 17.0 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Peptidase_M75 PF09375.10 PXF48969.1 - 0.098 12.1 0.2 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Imelysin Sulfotransfer_2 PF03567.14 PXF48970.1 - 1.6e-05 24.9 0.2 2.3e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Sulfotransferase family CNOT1_TTP_bind PF16417.5 PXF48971.1 - 1e-45 155.3 0.0 1.7e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 PXF48971.1 - 5.4e-40 137.2 0.9 8.2e-40 136.6 0.9 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 PXF48972.1 - 1.5e-10 41.2 0.2 2.8e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_CAF1_bind PF16415.5 PXF48972.1 - 1.3e-07 31.3 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain OrsD PF12013.8 PXF48973.1 - 0.00034 21.0 0.2 0.00077 19.9 0.2 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Di19 PF05605.12 PXF48973.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 PXF48973.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-NADH-PPase PF09297.11 PXF48973.1 - 0.085 12.5 0.2 18 5.1 0.0 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Mem_trans PF03547.18 PXF48974.1 - 6.4e-18 64.3 3.2 3e-13 49.0 1.5 2.4 1 1 1 2 2 2 2 Membrane transport protein RNA_ligase PF09414.10 PXF48975.1 - 3e-22 79.6 0.0 8.5e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 RNA ligase AAA_33 PF13671.6 PXF48975.1 - 1.3e-06 28.6 1.0 6.7e-05 23.1 0.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PXF48975.1 - 0.00082 19.9 0.0 0.0058 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain DSPc PF00782.20 PXF48975.1 - 0.00083 19.2 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain KTI12 PF08433.10 PXF48975.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PTPlike_phytase PF14566.6 PXF48975.1 - 0.02 15.0 0.3 0.041 14.0 0.3 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_16 PF13191.6 PXF48975.1 - 0.022 15.1 0.0 0.56 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain 6PF2K PF01591.18 PXF48975.1 - 0.026 13.8 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 PXF48975.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 PXF48975.1 - 0.082 13.2 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thioredoxin_13 PF18401.1 PXF48975.1 - 0.16 11.9 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain peroxidase PF00141.23 PXF48976.1 - 7.8e-07 29.0 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FBA PF04300.13 PXF48977.1 - 3.6e-14 52.8 0.1 1.9e-13 50.5 0.1 2.1 1 1 0 1 1 1 1 F-box associated region zf-RING_11 PF17123.5 PXF48977.1 - 6.4e-08 32.2 6.0 2.5e-07 30.3 6.0 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 PXF48977.1 - 0.00014 22.2 8.2 0.00014 22.2 8.2 4.1 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF48977.1 - 0.00016 21.5 3.8 0.00016 21.5 3.8 3.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF48977.1 - 0.00037 20.4 2.3 0.0021 18.0 2.3 2.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PXF48977.1 - 0.0084 15.7 2.3 0.0084 15.7 2.3 3.7 4 0 0 4 4 4 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PXF48977.1 - 0.014 15.7 1.6 0.014 15.7 1.6 3.6 2 1 2 4 4 4 0 RING-H2 zinc finger domain EamA PF00892.20 PXF48978.1 - 1.8e-05 24.9 19.9 0.002 18.3 5.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family PMT_2 PF13231.6 PXF48978.1 - 0.97 9.6 12.9 0.2 11.9 0.6 3.3 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase UPF0020 PF01170.18 PXF48979.1 - 4.7e-27 95.0 0.1 7.2e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 PXF48979.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 PXF48979.1 - 0.076 13.7 0.0 0.35 11.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain LRR_6 PF13516.6 PXF48980.1 - 2.8e-13 48.7 13.0 0.0014 18.5 0.4 7.2 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 PXF48980.1 - 4.8e-10 39.5 3.2 0.6 10.6 0.0 6.2 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PXF48980.1 - 2.3e-06 27.4 0.5 3.4 8.6 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 PXF48980.1 - 1.6e-05 24.6 2.6 15 5.4 0.0 6.0 4 1 1 5 5 5 3 Leucine rich repeat PNK3P PF08645.11 PXF48982.1 - 1.3e-51 174.5 0.0 2e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 PXF48982.1 - 3.8e-16 59.5 1.2 2.2e-07 31.1 0.2 2.8 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.10 PXF48982.1 - 0.0046 16.4 0.2 0.64 9.4 0.2 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 PXF48982.1 - 0.006 15.9 0.2 0.69 9.2 0.1 2.2 1 1 0 2 2 2 2 Zeta toxin CPT PF07931.12 PXF48982.1 - 0.16 11.8 0.0 25 4.7 0.0 2.4 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Pkinase PF00069.25 PXF48983.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF48983.1 - 2.2e-06 27.8 0.0 3.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF48983.1 - 4.8e-06 26.3 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PXF48983.1 - 4.9e-05 22.7 0.0 6.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF48983.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PXF48983.1 - 0.0061 15.4 0.0 0.052 12.3 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase SHOCT PF09851.9 PXF48984.1 - 0.00043 19.9 0.3 0.00043 19.9 0.3 2.3 2 0 0 2 2 2 1 Short C-terminal domain Sgf11_N PF18519.1 PXF48984.1 - 0.077 12.6 0.1 0.28 10.8 0.1 2.0 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain DUF4218 PF13960.6 PXF48986.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) GUN4_N PF16416.5 PXF48986.1 - 0.15 12.1 0.5 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal Thiolase_N PF00108.23 PXF48989.1 - 1.3e-92 309.9 0.1 1.7e-92 309.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PXF48989.1 - 3.4e-45 152.7 0.3 2.5e-43 146.6 0.2 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PXF48989.1 - 5.3e-05 22.9 1.4 5.3e-05 22.9 1.4 3.8 3 1 2 5 5 5 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PXF48989.1 - 0.028 14.4 0.1 10 6.2 0.0 3.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 PXF48989.1 - 0.48 10.3 3.7 22 5.0 0.1 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PPDK_N PF01326.19 PXF48990.1 - 4.9e-24 85.2 4.3 5.1e-18 65.4 0.0 4.2 2 1 1 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SAGA-Tad1 PF12767.7 PXF48990.1 - 0.019 14.7 0.4 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit NARP1 PF12569.8 PXF48990.1 - 0.16 10.9 8.4 0.24 10.3 8.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MRP-L47 PF06984.13 PXF48991.1 - 3e-22 78.5 0.1 4.5e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 PXF48991.1 - 1.8e-05 24.6 0.1 0.00025 20.9 0.0 2.4 2 1 0 2 2 2 1 Ribosomal L29 protein NodZ PF05830.11 PXF48992.1 - 0.00012 21.0 0.1 0.061 12.1 0.0 3.1 3 0 0 3 3 3 2 Nodulation protein Z (NodZ) XG_FTase PF03254.13 PXF48992.1 - 0.045 12.4 0.0 1.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Xyloglucan fucosyltransferase MFS_1 PF07690.16 PXF48994.1 - 1.2e-36 126.4 41.0 1.2e-36 126.4 41.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 PXF48994.1 - 0.0045 15.9 2.7 0.011 14.5 2.7 1.6 1 0 0 1 1 1 1 POT family Rubredoxin PF00301.20 PXF48995.1 - 0.00097 19.1 6.0 0.031 14.3 6.0 2.3 1 1 0 1 1 1 1 Rubredoxin ORC5_C PF14630.6 PXF48995.1 - 0.045 13.3 6.7 1.9 7.9 1.7 2.2 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Zn_Tnp_IS1595 PF12760.7 PXF48995.1 - 0.063 13.3 0.3 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Spt20 PF12090.8 PXF48995.1 - 0.089 12.4 12.8 0.034 13.7 7.6 2.2 2 0 0 2 2 2 0 Spt20 family Eapp_C PF10238.9 PXF48995.1 - 0.14 12.3 7.7 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein EPL1 PF10513.9 PXF48995.1 - 0.14 12.5 4.4 0.16 12.3 0.9 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 PXF48995.1 - 0.19 10.6 28.0 0.75 8.7 2.1 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Zn-ribbon_8 PF09723.10 PXF48995.1 - 0.23 11.6 3.2 1 9.5 3.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain TFIIA PF03153.13 PXF48995.1 - 0.25 11.3 14.3 0.054 13.5 7.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF35_N PF12172.8 PXF48995.1 - 0.51 10.3 3.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CSRNP_N PF16019.5 PXF48995.1 - 0.82 9.5 7.9 0.54 10.1 2.5 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Rubredoxin_2 PF18073.1 PXF48995.1 - 1.1 9.1 3.0 6.6 6.6 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Androgen_recep PF02166.16 PXF48995.1 - 3.5 6.4 12.7 0.13 11.1 6.8 1.5 2 0 0 2 2 2 0 Androgen receptor DUF4611 PF15387.6 PXF48995.1 - 3.7 7.8 7.1 0.55 10.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ANAPC_CDC26 PF10471.9 PXF48995.1 - 4.7 8.1 20.6 16 6.4 1.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Neur_chan_memb PF02932.16 PXF48995.1 - 9.3 6.2 7.0 2.5 8.1 2.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Elf1 PF05129.13 PXF48996.1 - 0.63 10.1 4.6 1.5 8.9 4.6 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like SF3b1 PF08920.10 PXF48997.1 - 9.4e-31 106.8 2.5 9.4e-31 106.8 2.5 3.6 1 1 2 3 3 3 1 Splicing factor 3B subunit 1 HEAT PF02985.22 PXF48997.1 - 2.3e-12 46.0 2.6 2.1 8.9 0.0 9.1 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 PXF48997.1 - 6.7e-11 42.4 2.5 2 8.9 0.0 7.6 4 3 5 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 PXF48997.1 - 4.8e-08 33.3 6.7 0.022 15.3 0.0 6.7 8 0 0 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PXF48997.1 - 1.3e-06 28.9 0.0 0.066 13.8 0.0 3.8 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PXF48997.1 - 2.2e-06 27.8 0.9 0.025 14.6 0.0 5.4 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 PXF48997.1 - 0.00081 19.1 0.4 3.6 7.2 0.0 3.7 3 1 0 3 3 3 2 NUC173 domain Adaptin_N PF01602.20 PXF48997.1 - 0.00093 17.9 0.2 2.4 6.6 0.3 3.4 1 1 0 3 3 3 2 Adaptin N terminal region Pet100 PF09803.9 PXF48998.1 - 3.2e-05 24.4 0.0 4.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Pet100 Nuf2 PF03800.14 PXF48999.1 - 1.3e-29 103.1 0.2 1.3e-29 103.1 0.2 2.5 3 1 0 3 3 3 1 Nuf2 family EccE PF11203.8 PXF48999.1 - 0.48 10.8 3.2 1.5 9.2 3.2 2.1 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE FUSC PF04632.12 PXF48999.1 - 0.87 8.0 14.7 0.044 12.3 7.6 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family ERM PF00769.19 PXF48999.1 - 0.99 9.2 58.2 1.6 8.5 30.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3365 PF11845.8 PXF48999.1 - 4.4 7.6 11.3 0.26 11.6 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Tropomyosin_1 PF12718.7 PXF48999.1 - 5 7.3 55.0 0.057 13.6 25.7 3.9 1 1 3 4 4 4 0 Tropomyosin like DUF3450 PF11932.8 PXF48999.1 - 8.7 5.6 37.5 1.8 7.8 14.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) EamA PF00892.20 PXF49001.1 - 7.8e-22 77.9 16.7 1.5e-12 47.9 0.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 PXF49001.1 - 0.00015 21.1 4.5 0.0012 18.2 1.6 2.2 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport CRT-like PF08627.10 PXF49001.1 - 0.046 12.7 0.4 0.074 12.0 0.4 1.2 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 PXF49001.1 - 0.12 11.6 8.9 0.35 10.2 1.2 2.2 1 1 1 2 2 2 0 Triose-phosphate Transporter family TPR_1 PF00515.28 PXF49002.1 - 9.8e-25 85.3 6.7 1.1e-08 34.5 0.1 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49002.1 - 1.5e-17 62.2 13.6 1.6e-05 24.7 0.2 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49002.1 - 2.3e-11 43.8 12.5 1.6e-07 31.5 1.2 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49002.1 - 1.1e-10 40.7 8.3 0.00041 20.2 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49002.1 - 1.2e-10 41.8 13.7 4.4e-05 24.0 1.0 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49002.1 - 1e-09 37.8 10.1 0.004 17.3 0.2 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 PXF49002.1 - 9.9e-08 31.6 14.8 0.0039 17.0 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF49002.1 - 2.8e-07 30.7 12.3 0.019 15.6 0.3 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49002.1 - 4.8e-07 29.7 4.7 1.4 9.4 0.8 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49002.1 - 1.6e-06 27.7 14.0 0.0027 17.3 0.0 6.2 4 2 2 6 6 6 2 TPR repeat TPR_9 PF13371.6 PXF49002.1 - 4.7e-06 26.7 0.7 0.0022 18.1 0.3 3.2 1 1 3 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF49002.1 - 5e-06 26.6 1.3 0.016 15.5 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PXF49002.1 - 1.7e-05 25.2 2.3 0.2 12.2 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49002.1 - 0.0013 19.3 14.5 3.6 8.6 0.3 6.1 1 1 6 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 PXF49002.1 - 0.036 14.7 1.3 2.1 9.2 0.3 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 PXF49002.1 - 0.048 13.6 3.8 1.7 8.5 0.2 2.6 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 PXF49002.1 - 0.049 14.1 3.2 3.1 8.2 0.1 2.7 1 1 2 3 3 3 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 PXF49002.1 - 0.41 10.7 2.5 6.7 6.9 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 PXF49002.1 - 0.88 9.7 11.2 5.4 7.1 0.1 3.9 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Sulfotransfer_3 PF13469.6 PXF49003.1 - 0.013 15.8 0.0 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Sulfotransferase family HypD PF01924.16 PXF49003.1 - 0.043 12.9 0.1 0.64 9.0 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase formation hypA family Sulfotransfer_1 PF00685.27 PXF49003.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase domain TPR_2 PF07719.17 PXF49004.1 - 6.5e-12 44.6 0.4 0.0054 16.7 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49004.1 - 1.4e-10 41.7 0.1 6.9e-09 36.2 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49004.1 - 5.7e-10 39.6 0.9 2.6e-06 27.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49004.1 - 1.7e-08 34.3 0.1 8.3e-06 25.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49004.1 - 2e-07 30.7 0.2 0.034 14.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49004.1 - 4.9e-07 29.3 0.0 0.004 16.8 0.0 4.0 3 1 1 4 4 4 2 TPR repeat TPR_7 PF13176.6 PXF49004.1 - 8.1e-07 28.6 0.2 1.1 9.4 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PXF49004.1 - 2.4e-06 27.1 0.1 0.0066 16.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49004.1 - 2.3e-05 24.6 11.5 0.36 11.1 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49004.1 - 8.4e-05 23.1 9.2 0.36 11.8 0.0 6.7 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49004.1 - 0.00033 20.8 0.0 0.00033 20.8 0.0 4.6 6 1 1 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 PXF49004.1 - 0.0082 16.6 0.2 0.059 13.8 0.0 2.6 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 PXF49004.1 - 0.099 12.5 4.3 0.12 12.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 PXF49005.1 - 7e-18 64.2 0.0 1.5e-17 63.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF49005.1 - 0.0064 16.1 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PXF49005.1 - 0.0085 16.2 0.0 0.026 14.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 PXF49005.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nop53 PF07767.11 PXF49005.1 - 7.2 5.9 28.5 9.7 5.5 28.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ThiF PF00899.21 PXF49006.1 - 2.2e-59 200.8 0.0 2.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 PXF49006.1 - 1.1e-08 35.5 0.0 3.7e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain ApbA PF02558.16 PXF49006.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 PXF49006.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.23 PXF49007.1 - 8.9e-72 241.7 0.2 1.8e-71 240.7 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF49007.1 - 1.2e-21 77.1 0.0 6.6e-21 74.7 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.6 PXF49007.1 - 5.6e-12 46.1 4.1 5.6e-12 46.1 4.1 4.1 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 PXF49007.1 - 6.7e-10 39.2 0.2 2.7e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PXF49007.1 - 4.6e-09 35.8 0.0 1.3e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.13 PXF49007.1 - 0.0043 17.3 13.8 0.0043 17.3 13.8 2.5 2 0 0 2 2 2 1 HSA Pho88 PF10032.9 PXF49008.1 - 1.6e-28 99.2 3.5 6.8e-26 90.6 3.5 2.1 1 1 0 1 1 1 1 Phosphate transport (Pho88) Kei1 PF08552.11 PXF49008.1 - 0.025 14.4 0.9 0.049 13.5 0.9 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CPSF100_C PF13299.6 PXF49008.1 - 0.029 14.5 4.2 0.048 13.8 0.4 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal ATG22 PF11700.8 PXF49008.1 - 0.082 11.5 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like EST1 PF10374.9 PXF49008.1 - 0.2 12.3 0.9 0.56 10.8 0.9 1.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 DUF4820 PF16091.5 PXF49008.1 - 0.78 9.1 6.6 0.28 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Vfa1 PF08432.10 PXF49008.1 - 0.87 9.9 14.8 0.36 11.2 4.6 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mak16 PF04874.14 PXF49008.1 - 1.8 9.2 12.5 0.53 10.9 2.3 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region Tim54 PF11711.8 PXF49008.1 - 4.2 6.1 13.4 0.021 13.7 1.0 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FYDLN_acid PF09538.10 PXF49008.1 - 8.5 7.1 18.2 9.6 6.9 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sulfotransfer_3 PF13469.6 PXF49010.1 - 0.045 14.1 0.2 0.67 10.3 0.2 2.2 1 1 0 1 1 1 0 Sulfotransferase family DUF1137 PF06587.11 PXF49011.1 - 0.13 12.3 0.3 0.33 11.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) DUF498 PF04430.14 PXF49012.1 - 3.7e-31 107.4 0.0 4.6e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) MFS_1 PF07690.16 PXF49013.1 - 7.1e-40 137.0 54.7 3e-37 128.4 34.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.21 PXF49013.1 - 0.0076 15.1 1.2 0.018 13.9 1.2 1.6 1 0 0 1 1 1 1 POT family UPF0121 PF03661.13 PXF49013.1 - 0.028 13.8 0.6 0.15 11.4 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Hist_deacetyl PF00850.19 PXF49014.1 - 2.2e-69 234.3 0.0 2.9e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RHD3 PF05879.12 PXF49015.1 - 1.3e-24 86.4 0.0 1.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) PPR PF01535.20 PXF49017.1 - 0.00055 20.0 0.1 91 3.7 0.0 5.3 6 0 0 6 6 6 0 PPR repeat TPR_19 PF14559.6 PXF49017.1 - 0.086 13.4 0.2 9.7 6.8 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat OMP_b-brl PF13505.6 PXF49019.1 - 0.0028 17.8 0.5 0.0043 17.2 0.5 1.3 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Porin_4 PF13609.6 PXF49019.1 - 0.017 14.9 1.0 0.028 14.2 1.0 1.3 1 0 0 1 1 1 0 Gram-negative porin CTP_transf_1 PF01148.20 PXF49020.1 - 2.6e-53 181.5 16.1 3.5e-53 181.1 16.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family UL45 PF05473.12 PXF49020.1 - 0.053 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like WD40 PF00400.32 PXF49021.1 - 0.0046 17.8 7.7 4 8.5 0.0 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF49021.1 - 0.17 12.2 0.0 8.6 6.7 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Asn_synthase PF00733.21 PXF49022.1 - 8.6e-18 65.1 1.0 7.2e-07 29.2 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 PXF49022.1 - 4.9e-07 29.7 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Cullin PF00888.22 PXF49024.1 - 2.5e-190 634.2 14.7 8.8e-106 354.9 4.2 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 PXF49024.1 - 2.3e-24 85.2 2.5 2.3e-24 85.2 2.5 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain TrmB PF01978.19 PXF49024.1 - 0.0096 15.8 1.0 1.8 8.5 0.5 2.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 PXF49024.1 - 0.019 15.1 0.5 0.35 11.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 PXF49024.1 - 0.022 14.5 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_5 PF01022.20 PXF49024.1 - 0.15 11.9 0.1 0.45 10.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Penicillinase_R PF03965.16 PXF49024.1 - 0.17 12.3 5.5 0.075 13.4 0.7 2.9 3 0 0 3 3 3 0 Penicillinase repressor HTH_24 PF13412.6 PXF49024.1 - 0.21 11.2 1.4 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Cupin_4 PF08007.12 PXF49025.1 - 3.4e-61 207.5 0.0 4.4e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 PXF49025.1 - 1.3e-05 25.1 1.4 9.8e-05 22.3 0.1 2.7 3 1 1 4 4 4 1 AraC-like ligand binding domain Cupin_2 PF07883.11 PXF49025.1 - 0.0001 21.9 0.2 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 PXF49025.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Cupin 60KD_IMP PF02096.20 PXF49026.1 - 9.4e-27 93.9 1.6 1.8e-26 93.0 1.6 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein GCN5L1 PF06320.13 PXF49027.1 - 1.4e-21 76.8 4.1 1.6e-21 76.6 4.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) APG17 PF04108.12 PXF49027.1 - 0.0021 17.3 2.2 0.0023 17.1 2.2 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 UPF0180 PF03698.13 PXF49027.1 - 0.0058 16.8 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0180) COG2 PF06148.11 PXF49027.1 - 0.011 15.8 1.7 0.074 13.1 1.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc29 PF17082.5 PXF49027.1 - 0.024 14.5 0.8 0.025 14.4 0.8 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF3958 PF13125.6 PXF49027.1 - 0.026 14.7 2.0 0.041 14.1 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Laminin_II PF06009.12 PXF49027.1 - 0.057 13.4 3.2 0.068 13.2 3.2 1.2 1 0 0 1 1 1 0 Laminin Domain II IlvN PF07991.12 PXF49027.1 - 0.063 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PBECR5 PF18814.1 PXF49027.1 - 0.064 13.2 0.9 0.071 13.0 0.9 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 DUF1664 PF07889.12 PXF49027.1 - 0.077 13.0 1.3 0.13 12.3 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 PXF49027.1 - 0.75 9.6 6.0 1.4 8.7 2.8 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF5446 PF17522.2 PXF49027.1 - 0.93 9.7 6.7 2.1 8.6 3.2 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5446) EMC3_TMCO1 PF01956.16 PXF49028.1 - 2.5e-33 115.2 0.2 4.2e-33 114.5 0.0 1.4 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Ribonuc_red_2_N PF08471.10 PXF49028.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase EPSP_synthase PF00275.20 PXF49029.1 - 1.7e-136 455.2 0.0 2e-136 455.0 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GPP34 PF05719.11 PXF49029.1 - 0.07 13.2 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) CHGN PF05679.16 PXF49030.1 - 1.3e-48 166.1 0.2 1.8e-48 165.7 0.2 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 PXF49030.1 - 0.0002 21.0 0.4 0.00045 19.8 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 PXF49030.1 - 0.076 12.7 0.0 0.45 10.2 0.0 2.2 1 1 1 2 2 2 0 N-terminal region of glycosyl transferase group 7 Urb2 PF10441.9 PXF49031.1 - 4.5 7.2 7.8 4.5 7.2 0.8 3.2 2 1 1 4 4 4 0 Urb2/Npa2 family DNA_photolyase PF00875.18 PXF49032.1 - 3.4e-16 59.7 0.1 2.6e-15 56.8 0.1 2.0 1 1 0 1 1 1 1 DNA photolyase TPR_2 PF07719.17 PXF49033.1 - 3.8e-22 76.5 3.6 0.0062 16.6 0.1 8.0 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49033.1 - 1.2e-20 72.4 24.0 0.0012 19.5 1.2 8.5 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49033.1 - 6.1e-18 63.8 0.0 0.0051 17.1 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49033.1 - 2.4e-14 53.6 3.9 0.013 16.0 0.1 5.3 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49033.1 - 2.7e-12 46.8 13.3 5.8e-07 29.7 1.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49033.1 - 9.3e-09 34.8 0.0 0.82 10.0 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49033.1 - 3.1e-08 34.1 14.4 0.05 14.3 1.3 5.3 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PXF49033.1 - 4.4e-08 32.6 0.0 3.8 7.5 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 PXF49033.1 - 5.7e-07 29.0 14.1 0.038 13.2 2.9 4.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49033.1 - 9.9e-05 22.4 24.6 0.093 12.9 3.6 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49033.1 - 0.0021 18.0 2.8 14 6.0 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF49033.1 - 0.0037 17.2 5.0 4.9 7.2 0.2 5.0 3 2 2 6 6 6 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 PXF49033.1 - 0.0045 17.5 5.9 38 5.2 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TetR_C_32 PF09209.11 PXF49033.1 - 0.009 16.0 0.4 0.031 14.2 0.3 1.9 2 0 0 2 2 1 1 Tetracyclin repressor-like, C-terminal domain MIT PF04212.18 PXF49033.1 - 0.014 15.5 0.1 96 3.2 0.0 4.7 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 PXF49033.1 - 0.043 12.7 0.1 1.6 7.5 0.0 2.6 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 PrmC_N PF17827.1 PXF49033.1 - 0.26 11.9 3.4 30 5.3 0.2 4.0 3 2 1 4 4 3 0 PrmC N-terminal domain ANAPC3 PF12895.7 PXF49033.1 - 0.63 10.3 5.0 1.8 8.8 0.2 3.4 2 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 PXF49033.1 - 3.2 8.2 10.4 10 6.6 2.8 3.4 2 2 1 3 3 3 0 Bacterial transcriptional activator domain Glycos_transf_2 PF00535.26 PXF49034.1 - 1.4e-18 67.3 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF49034.1 - 5.8e-13 49.3 0.1 3.5e-12 46.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PXF49034.1 - 2e-06 27.5 0.0 0.0041 16.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 PALP PF00291.25 PXF49034.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.24 PXF49035.1 - 3e-120 402.1 2.0 3.8e-120 401.8 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 PXF49035.1 - 2.3e-42 144.0 0.7 3.5e-42 143.4 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 PXF49035.1 - 0.0042 16.2 1.6 0.23 10.5 3.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 PXF49035.1 - 0.0044 16.3 0.7 0.46 9.7 0.3 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 PXF49035.1 - 0.013 14.8 3.5 0.043 13.0 1.8 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PXF49035.1 - 0.023 14.0 0.6 0.04 13.2 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 PXF49035.1 - 5.6 6.2 11.7 0.3 10.4 3.4 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pkinase PF00069.25 PXF49036.1 - 3.9e-65 219.8 0.0 4.6e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49036.1 - 1.6e-23 83.3 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49036.1 - 1.9e-06 27.4 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PXF49036.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF49036.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PXF49036.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 PXF49036.1 - 0.049 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L21p PF00829.21 PXF49037.1 - 4.7e-30 103.8 0.1 8.2e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ion_trans PF00520.31 PXF49038.1 - 7.5e-17 61.4 8.2 1e-16 60.9 8.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ribosomal_S6e PF01092.19 PXF49039.1 - 7.6e-49 164.9 0.3 1.4e-48 164.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Complex1_LYR PF05347.15 PXF49040.1 - 3.3e-12 46.3 0.2 3.9e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PXF49040.1 - 1.7e-05 25.5 0.1 1.8e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PXF49040.1 - 8.5e-05 23.1 0.1 9.5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.25 PXF49041.1 - 7e-57 192.8 0.0 9.9e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49041.1 - 1.2e-33 116.5 0.0 1.8e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PXF49041.1 - 6.5e-07 28.5 1.4 2.2e-06 26.7 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 PXF49041.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Kinase-like CBM_5_12_2 PF14600.6 PXF49041.1 - 0.03 14.2 0.2 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Cellulose-binding domain HEAT_2 PF13646.6 PXF49042.1 - 8.6e-06 26.1 0.3 0.0037 17.6 0.0 3.3 2 1 0 2 2 2 2 HEAT repeats Med19 PF10278.9 PXF49042.1 - 0.19 11.6 14.1 0.45 10.4 14.1 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 HEAT PF02985.22 PXF49042.1 - 0.22 11.9 1.3 2.4 8.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat UQ_con PF00179.26 PXF49043.1 - 6.1e-38 129.6 0.0 8.2e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PXF49043.1 - 0.00053 19.7 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 PXF49043.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 UEV domain NEMO PF11577.8 PXF49048.1 - 0.019 15.0 0.4 0.037 14.0 0.4 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO RasGAP_C PF03836.15 PXF49048.1 - 0.057 13.6 0.2 0.067 13.3 0.2 1.1 1 0 0 1 1 1 0 RasGAP C-terminus FlaC_arch PF05377.11 PXF49048.1 - 0.11 12.9 0.3 0.11 12.9 0.3 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 PXF49048.1 - 0.19 12.4 0.9 0.28 11.8 0.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Sas10_Utp3 PF04000.15 PXF49050.1 - 4.5e-12 46.4 0.0 4.5e-12 46.4 0.0 3.3 2 1 0 3 3 3 1 Sas10/Utp3/C1D family DAO PF01266.24 PXF49051.1 - 7.9e-47 160.5 0.2 1e-46 160.1 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF49051.1 - 1.9e-07 30.6 0.1 3.3e-06 26.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF49051.1 - 1.4e-06 27.7 0.5 0.0016 17.6 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PXF49051.1 - 2.6e-06 26.8 0.3 7.9e-06 25.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 PXF49051.1 - 0.00023 21.3 1.5 0.00051 20.2 1.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PXF49051.1 - 0.00051 19.4 0.0 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PXF49051.1 - 0.00063 18.6 0.6 0.0044 15.8 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 PXF49051.1 - 0.0026 16.7 0.2 0.73 8.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 PXF49051.1 - 0.0037 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 PXF49051.1 - 0.0045 16.1 0.3 0.017 14.2 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 PXF49051.1 - 0.0089 15.4 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Stm1_N PF09598.10 PXF49051.1 - 0.0091 16.8 1.6 0.0091 16.8 1.6 2.1 2 0 0 2 2 1 1 Stm1 Pyr_redox_3 PF13738.6 PXF49051.1 - 0.028 13.7 0.0 0.075 12.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nramp PF01566.18 PXF49052.1 - 9.9e-83 278.0 19.2 9.9e-83 278.0 19.2 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Trypan_PARP PF05887.11 PXF49053.1 - 0.0023 17.9 31.0 0.0023 17.9 31.0 5.0 2 1 2 5 5 5 3 Procyclic acidic repetitive protein (PARP) PRKG1_interact PF15898.5 PXF49053.1 - 2.2 9.2 6.9 2.2 9.2 0.1 3.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain PP1c_bdg PF10488.9 PXF49053.1 - 5.2 6.5 11.8 0.4 10.1 6.4 1.8 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region SNF2_N PF00176.23 PXF49054.1 - 4.1e-63 213.2 0.0 9.2e-63 212.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 PXF49054.1 - 2.3e-33 116.1 2.5 1.9e-32 113.1 0.8 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 PXF49054.1 - 3.5e-16 59.5 0.0 1e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 PXF49054.1 - 1.5e-13 49.7 13.8 0.047 14.0 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 PXF49054.1 - 5.7e-10 39.5 22.3 0.014 15.7 0.1 8.1 8 1 1 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 PXF49054.1 - 3e-07 30.8 19.7 0.06 13.9 0.0 8.5 10 0 0 10 10 10 3 HEAT-like repeat ResIII PF04851.15 PXF49054.1 - 2.1e-06 27.8 0.0 5.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 PXF49054.1 - 4.8e-05 23.9 1.9 0.57 10.8 0.0 4.2 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 PXF49054.1 - 0.00027 20.7 0.5 3.2 7.4 0.0 4.3 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 PXF49054.1 - 0.14 12.1 0.6 20 5.2 0.0 3.8 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ArgJ PF01960.18 PXF49055.1 - 8.5e-139 462.5 6.4 9.7e-139 462.3 6.4 1.0 1 0 0 1 1 1 1 ArgJ family dCMP_cyt_deam_1 PF00383.23 PXF49056.1 - 9.8e-22 76.7 1.6 1.3e-21 76.3 1.6 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PXF49056.1 - 1.9e-20 73.0 0.0 2.3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 PXF49056.1 - 5e-06 26.5 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 PXF49056.1 - 2.6e-05 24.3 0.0 4.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 PXF49056.1 - 0.00024 21.2 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 PXF49056.1 - 0.00028 21.0 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 PXF49056.1 - 0.0017 18.4 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 Bd3614-deam PF14439.6 PXF49056.1 - 0.0079 16.3 5.8 1.9 8.6 5.8 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase NAD2 PF18782.1 PXF49056.1 - 0.0094 16.1 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 PXF49056.1 - 0.023 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Pyr_redox_2 PF07992.14 PXF49057.1 - 9.9e-51 172.7 1.1 1.1e-50 172.5 1.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF49057.1 - 6.3e-20 71.5 0.1 5.5e-17 62.1 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PXF49057.1 - 3.2e-18 66.0 0.0 1.6e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF49057.1 - 4.2e-05 22.9 0.6 0.0018 17.5 0.0 2.5 2 1 0 2 2 2 1 Thi4 family GIDA PF01134.22 PXF49057.1 - 0.0013 17.9 2.6 3.6 6.6 0.1 3.8 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 PXF49057.1 - 0.0021 18.3 0.5 0.14 12.5 0.1 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PXF49057.1 - 0.0023 17.1 2.9 0.59 9.2 0.2 3.4 3 1 0 4 4 4 1 FAD binding domain NAD_binding_7 PF13241.6 PXF49057.1 - 0.0025 18.3 0.2 0.2 12.1 0.1 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PXF49057.1 - 0.0053 16.1 0.1 2.6 7.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 PXF49057.1 - 0.0079 15.4 0.1 0.78 8.8 0.1 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 PXF49057.1 - 0.008 15.6 1.1 0.86 8.9 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PXF49057.1 - 0.019 13.7 2.9 4.2 6.0 0.1 3.3 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 PXF49057.1 - 0.022 14.3 2.6 0.78 9.3 0.0 2.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 PXF49057.1 - 0.025 14.7 0.1 7.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_S6 PF01250.17 PXF49058.1 - 1.9e-13 50.5 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 DUF1104 PF06518.11 PXF49058.1 - 0.13 12.6 0.3 0.38 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) SWIB PF02201.18 PXF49060.1 - 5.7e-28 96.6 0.0 2e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 SWIB/MDM2 domain GatB_N PF02934.15 PXF49061.1 - 2.6e-110 368.1 0.0 3.3e-110 367.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 PXF49061.1 - 1.3e-42 145.2 0.1 1.8e-42 144.7 0.1 1.2 1 0 0 1 1 1 1 GatB domain MltA PF03562.17 PXF49062.1 - 0.044 13.6 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 MltA specific insert domain SBDS PF01172.18 PXF49063.1 - 9.7e-23 80.1 0.3 1.9e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 PXF49063.1 - 2.9e-07 30.5 0.3 5e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain ubiquitin PF00240.23 PXF49064.1 - 6.8e-22 77.0 0.1 6.1e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_5 PF18037.1 PXF49064.1 - 1.2e-08 35.2 4.0 0.00031 21.0 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-like domain Rad60-SLD PF11976.8 PXF49064.1 - 3.2e-06 26.9 0.0 0.00084 19.1 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PXF49064.1 - 4.5e-06 27.2 0.5 0.025 15.1 0.2 2.5 2 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PXF49064.1 - 0.00017 21.7 0.8 0.39 10.8 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PXF49064.1 - 0.0043 17.5 0.5 4.2 7.9 0.0 3.4 2 2 1 3 3 3 2 Ubiquitin-like domain YukD PF08817.10 PXF49064.1 - 0.013 16.2 0.0 1.5 9.6 0.0 2.7 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Methyltransf_11 PF08241.12 PXF49065.1 - 2.3e-18 66.6 0.0 4.1e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49065.1 - 1.1e-14 54.9 0.0 2.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PXF49065.1 - 1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49065.1 - 4.4e-11 42.9 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF49065.1 - 2.4e-10 40.2 0.0 9.3e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PXF49065.1 - 3.5e-06 27.7 0.0 7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PXF49065.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 PXF49065.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW AlaDh_PNT_C PF01262.21 PXF49065.1 - 0.14 11.4 0.0 10 5.4 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain MMR_HSR1_Xtn PF16897.5 PXF49066.1 - 4.4e-34 116.7 0.1 7.1e-34 116.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PXF49066.1 - 1.3e-20 73.6 0.0 2.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 PXF49066.1 - 4.7e-15 55.4 0.1 8.4e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 PXF49066.1 - 7.3e-09 35.3 0.0 3.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PXF49066.1 - 3.5e-06 27.2 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 Dynamin family zf-ZPR1 PF03367.13 PXF49066.1 - 0.0007 19.5 0.1 0.48 10.3 0.0 2.7 3 0 0 3 3 3 2 ZPR1 zinc-finger domain CP12 PF02672.15 PXF49067.1 - 3.8e-27 94.8 5.2 4.6e-27 94.6 5.2 1.1 1 0 0 1 1 1 1 CP12 domain zf-C2H2_4 PF13894.6 PXF49068.1 - 7.4e-07 29.5 16.3 0.039 14.8 3.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PXF49068.1 - 1.2e-05 25.4 7.7 0.29 11.5 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PXF49068.1 - 1.6e-05 25.1 14.4 0.033 14.6 2.9 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF49068.1 - 3.1e-05 24.2 18.0 0.0033 17.8 1.1 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 PXF49068.1 - 0.00085 19.6 8.5 0.71 10.3 1.3 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 PXF49068.1 - 0.0052 16.5 4.8 0.12 12.2 0.2 3.0 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 PXF49068.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 PXF49068.1 - 0.94 9.8 9.4 0.34 11.2 5.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.23 PXF49069.1 - 3.8e-07 30.3 0.5 7e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49069.1 - 0.0016 17.8 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2252 PF10009.9 PXF49069.1 - 0.032 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) HORMA PF02301.18 PXF49070.1 - 2.6e-40 138.3 0.1 8.9e-40 136.5 0.1 1.9 1 1 0 1 1 1 1 HORMA domain DUF5615 PF18480.1 PXF49070.1 - 0.1 12.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) DUF1348 PF07080.11 PXF49071.1 - 1.3e-62 209.4 6.5 1.7e-62 209.1 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 PXF49071.1 - 2.9e-05 24.6 2.8 2.9e-05 24.6 2.8 1.6 2 0 0 2 2 2 1 SnoaL-like domain GAF_2 PF13185.6 PXF49071.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 GAF domain Jnk-SapK_ap_N PF09744.9 PXF49072.1 - 0.00039 20.7 1.7 0.00073 19.8 1.7 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 PXF49072.1 - 0.0096 16.1 4.4 0.0096 16.1 4.4 1.6 2 0 0 2 2 2 1 Tropomyosin like HAUS-augmin3 PF14932.6 PXF49072.1 - 0.011 15.3 3.2 0.018 14.7 3.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 PXF49072.1 - 0.013 15.3 4.0 0.023 14.5 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DLP_helical PF18709.1 PXF49072.1 - 0.028 13.7 1.7 0.05 12.8 1.7 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain CtIP_N PF10482.9 PXF49072.1 - 0.047 13.7 6.6 0.1 12.6 5.1 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain G-gamma PF00631.22 PXF49072.1 - 0.098 12.7 3.9 0.35 10.9 0.5 2.5 1 1 1 2 2 2 0 GGL domain Mod_r PF07200.13 PXF49072.1 - 0.1 12.7 10.0 0.059 13.5 7.2 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Lectin_N PF03954.14 PXF49072.1 - 0.11 12.2 4.9 0.27 11.0 4.9 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain YabA PF06156.13 PXF49072.1 - 0.26 11.9 3.4 1.1 9.9 3.6 2.0 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 PXF49072.1 - 0.27 11.7 9.1 2.4 8.6 9.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 PXF49072.1 - 0.47 10.7 7.0 1.2 9.4 6.8 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 PXF49072.1 - 0.64 10.4 6.2 1.5 9.2 6.2 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 PXF49072.1 - 0.71 10.1 5.0 0.5 10.6 1.9 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 PXF49072.1 - 0.99 9.3 5.7 4.7 7.2 0.6 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Uso1_p115_C PF04871.13 PXF49072.1 - 1.1 9.7 6.8 3.4 8.1 6.9 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 PXF49072.1 - 1.9 8.5 14.2 8 6.5 13.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.18 PXF49072.1 - 2.4 8.5 7.6 0.14 12.4 2.0 1.8 2 0 0 2 2 1 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 PXF49072.1 - 2.6 8.3 5.1 36 4.6 4.9 2.4 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Tmpp129 PF10272.9 PXF49073.1 - 0.035 13.4 4.6 0.05 12.9 4.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF5082 PF16888.5 PXF49073.1 - 0.13 12.6 11.9 0.73 10.1 11.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF2408 PF10303.9 PXF49073.1 - 1.1 9.8 9.8 1.9 9.0 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Phage_GPO PF05929.11 PXF49073.1 - 1.5 8.4 8.9 3.1 7.4 8.9 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Prefoldin PF02996.17 PXF49073.1 - 2.2 8.2 10.8 4 7.4 3.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit MscS_porin PF12795.7 PXF49073.1 - 4.5 6.7 28.1 0.24 10.9 22.2 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 PXF49073.1 - 5 6.6 14.7 8 5.9 14.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GLTP PF08718.11 PXF49074.1 - 2.3e-24 86.4 0.0 3.5e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Myb_DNA-binding PF00249.31 PXF49075.1 - 2.9e-08 33.8 0.1 4.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain GTP_EFTU PF00009.27 PXF49076.1 - 1.8e-34 119.0 2.1 1.3e-32 112.9 0.2 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PXF49076.1 - 2.5e-21 75.8 1.8 5.1e-21 74.8 1.1 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 PXF49076.1 - 3.2e-08 33.8 1.5 0.001 19.4 0.1 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF49076.1 - 3.6e-07 30.3 0.2 1.3e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 PXF49076.1 - 8.1e-05 22.4 0.4 0.048 13.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu domain 4 SRPRB PF09439.10 PXF49076.1 - 0.00035 20.0 0.0 0.002 17.6 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit ADIP PF11559.8 PXF49076.1 - 0.0046 17.1 1.3 0.011 15.9 1.3 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding PduV-EutP PF10662.9 PXF49076.1 - 0.0049 16.6 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 PXF49076.1 - 0.0098 15.4 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 PXF49076.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF49076.1 - 0.019 14.4 0.0 0.12 11.8 0.0 2.2 2 1 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 PXF49076.1 - 0.02 14.9 0.5 0.16 12.0 0.0 2.5 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 PXF49076.1 - 0.055 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Peptidase_S41 PF03572.18 PXF49076.1 - 0.059 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S41 F-box-like PF12937.7 PXF49077.1 - 2.2e-05 24.3 1.9 7e-05 22.6 1.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF49077.1 - 0.0074 16.1 1.7 0.018 14.9 0.1 2.6 3 0 0 3 3 3 1 F-box domain MAGI_u5 PF16666.5 PXF49077.1 - 1.9 8.7 6.3 4.2 7.5 6.3 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI Alpha-amylase PF00128.24 PXF49079.1 - 1.3e-16 61.1 0.0 2.9e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain PUD PF03714.14 PXF49079.1 - 5.4e-14 52.8 0.1 6e-05 23.8 0.1 3.7 3 0 0 3 3 3 3 Bacterial pullanase-associated domain CBM_48 PF02922.18 PXF49079.1 - 1.5e-07 31.6 0.0 5.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3372 PF11852.8 PXF49079.1 - 2.1e-05 24.0 0.0 5.7e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3372) hDGE_amylase PF14701.6 PXF49079.1 - 0.0015 17.7 0.5 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Trigger_N PF05697.13 PXF49080.1 - 3.8e-32 111.6 0.1 3.8e-32 111.6 0.1 2.9 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 PXF49080.1 - 2.9e-19 69.7 17.5 2.9e-19 69.7 17.5 2.5 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 PXF49080.1 - 0.00022 21.5 0.5 0.001 19.3 0.1 2.3 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase CPSase_L_D3 PF02787.19 PXF49080.1 - 0.12 12.7 1.2 0.34 11.2 0.4 2.1 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain G-patch PF01585.23 PXF49081.1 - 1.3e-14 53.8 3.5 1.3e-14 53.8 3.5 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PXF49081.1 - 2.4e-05 24.3 3.9 2.4e-05 24.3 3.9 2.7 2 1 0 2 2 2 1 G-patch domain AUDH_Cupin PF18637.1 PXF49082.1 - 1.5e-37 129.1 0.1 2.8e-37 128.2 0.1 1.4 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain VCBS PF13517.6 PXF49082.1 - 2.8e-09 37.4 16.2 1.1e-05 25.9 3.7 5.1 3 2 2 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 PXF49082.1 - 0.53 9.6 3.6 1.3 8.4 0.2 2.8 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 PXF49082.1 - 2.3 8.4 13.7 1.4 9.2 0.9 3.3 3 0 0 3 3 3 0 FG-GAP repeat EamA PF00892.20 PXF49083.1 - 3.5e-20 72.6 31.9 3.9e-11 43.3 8.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 PXF49083.1 - 0.11 11.4 1.3 8.3 5.2 0.3 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Col_cuticle_N PF01484.17 PXF49083.1 - 1.8 8.7 5.0 5.3 7.2 0.0 3.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain YceD PF02620.17 PXF49084.1 - 6.1e-11 42.5 0.1 9.6e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD NAD_binding_10 PF13460.6 PXF49085.1 - 1.7e-21 76.9 0.2 2.2e-21 76.6 0.2 1.0 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 PXF49085.1 - 0.00013 22.0 0.0 0.00027 21.1 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 PXF49085.1 - 0.0011 18.6 0.2 0.0023 17.5 0.2 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF49085.1 - 0.0029 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF547 PF04784.14 PXF49087.1 - 9.1e-25 87.1 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 PXF49087.1 - 5.7e-06 26.3 0.0 2.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Lysozyme_like PF13702.6 PXF49087.1 - 0.14 11.8 0.0 0.97 9.1 0.0 2.0 2 0 0 2 2 2 0 Lysozyme-like SAM_1 PF00536.30 PXF49088.1 - 3.8e-08 33.7 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Slx4 PF09494.10 PXF49088.1 - 0.0014 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease SAM_2 PF07647.17 PXF49088.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UBZ_FAAP20 PF15750.5 PXF49088.1 - 0.12 12.3 0.7 0.32 11.0 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DUF3450 PF11932.8 PXF49089.1 - 0.005 16.2 2.3 0.023 14.0 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF3584 PF12128.8 PXF49089.1 - 0.0093 13.5 1.9 0.012 13.2 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF2205 PF10224.9 PXF49089.1 - 0.0095 15.9 1.1 0.16 12.0 0.1 2.5 2 0 0 2 2 2 1 Short coiled-coil protein Rootletin PF15035.6 PXF49089.1 - 0.022 14.8 0.5 0.043 13.8 0.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 PXF49089.1 - 0.039 14.2 0.6 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper NEMO PF11577.8 PXF49089.1 - 0.046 13.7 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DDE_Tnp_1_4 PF13701.6 PXF49089.1 - 0.053 11.8 0.2 0.066 11.5 0.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 IL13 PF03487.13 PXF49089.1 - 0.055 13.2 0.6 0.15 11.8 0.2 1.8 2 0 0 2 2 2 0 Interleukin-13 Dehyd-heme_bind PF09098.10 PXF49089.1 - 0.069 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding FlaC_arch PF05377.11 PXF49089.1 - 0.17 12.3 2.3 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 PXF49089.1 - 0.19 12.2 2.6 1.8 9.1 2.6 2.5 1 1 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 PXF49089.1 - 0.21 11.8 2.1 1.5 9.1 1.5 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PXF49089.1 - 0.25 10.2 3.2 0.31 9.9 1.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Tup_N PF08581.10 PXF49089.1 - 0.91 9.9 4.0 0.88 9.9 0.1 2.6 2 1 1 3 3 3 0 Tup N-terminal Snapin_Pallidin PF14712.6 PXF49089.1 - 1.7 9.1 5.1 1.5 9.3 0.1 2.8 2 1 1 3 3 3 0 Snapin/Pallidin TPR_MLP1_2 PF07926.12 PXF49089.1 - 3.3 7.8 6.1 0.28 11.2 0.4 2.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 PXF49089.1 - 3.9 7.1 7.1 0.41 10.3 0.3 2.4 2 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease PP_kinase_C_1 PF17941.1 PXF49090.1 - 7.6e-62 207.8 0.0 1.6e-60 203.5 0.0 2.4 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 PXF49090.1 - 3.2e-55 186.2 0.0 1.3e-54 184.3 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 PXF49090.1 - 7.2e-40 136.7 0.0 1.2e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 PXF49090.1 - 3.5e-17 62.7 0.0 7.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 PXF49090.1 - 2.1e-16 60.0 0.0 6.9e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain NUDIX PF00293.28 PXF49090.1 - 2.1e-07 31.0 0.2 4.5e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain Synaptobrevin PF00957.21 PXF49092.1 - 1.3e-25 89.0 3.8 2.1e-25 88.3 3.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PXF49092.1 - 5.5e-10 39.1 0.1 1.2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 PXF49092.1 - 0.028 14.5 0.6 0.037 14.1 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter rve_3 PF13683.6 PXF49092.1 - 0.081 12.7 0.2 0.25 11.1 0.2 1.9 1 0 0 1 1 1 0 Integrase core domain Fzo_mitofusin PF04799.13 PXF49092.1 - 0.14 11.7 2.6 0.17 11.5 1.9 1.6 1 1 0 1 1 1 0 fzo-like conserved region SNARE PF05739.19 PXF49092.1 - 1.5 8.9 5.3 0.97 9.5 2.4 2.2 2 0 0 2 2 2 0 SNARE domain IF-2B PF01008.17 PXF49093.1 - 7.2e-08 32.0 1.8 1.5e-07 30.9 1.8 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family YdjC PF04794.12 PXF49093.1 - 0.15 12.0 0.2 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 YdjC-like protein Ribosomal_L14 PF00238.19 PXF49096.1 - 1.6e-33 115.4 0.3 1.8e-33 115.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-B_box PF00643.24 PXF49097.1 - 4e-14 52.5 14.3 1.1e-07 31.9 2.7 2.5 2 0 0 2 2 2 2 B-box zinc finger ArfGap PF01412.18 PXF49097.1 - 0.57 10.3 8.9 0.24 11.5 2.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF2318 PF10080.9 PXF49097.1 - 1.4 9.1 12.2 2.5 8.3 2.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Pol_alpha_B_N PF08418.10 PXF49097.1 - 2.4 8.1 6.5 3.9 7.4 6.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-C3HC4_3 PF13920.6 PXF49097.1 - 6.7 6.6 12.9 3.7 7.5 4.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.27 PXF49098.1 - 8.3e-06 25.3 8.9 2.2e-05 23.9 8.9 1.8 1 1 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 PXF49098.1 - 0.7 9.9 4.8 1.7 8.6 1.6 2.6 2 0 0 2 2 2 0 Nudix N-terminal Cpn10 PF00166.21 PXF49099.1 - 7.4e-16 58.0 0.0 8.5e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Rad60-SLD_2 PF13881.6 PXF49100.1 - 1.8e-13 50.5 0.0 3.9e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PXF49100.1 - 2.8e-06 27.0 0.0 0.016 15.0 0.0 2.5 2 1 1 3 3 3 2 Ubiquitin family UBX PF00789.20 PXF49100.1 - 0.041 14.1 0.1 0.16 12.1 0.0 2.1 1 1 1 2 2 2 0 UBX domain DUF1296 PF06972.11 PXF49100.1 - 0.063 13.4 3.5 1.8 8.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) Methyltransf_11 PF08241.12 PXF49101.1 - 7.4e-17 61.8 0.0 2e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49101.1 - 4.4e-16 59.4 0.1 1.3e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain UPF0203 PF05254.12 PXF49101.1 - 3e-13 49.8 3.1 7.3e-13 48.6 3.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Methyltransf_31 PF13847.6 PXF49101.1 - 1.9e-12 47.2 0.0 4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49101.1 - 2.1e-11 43.9 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PXF49101.1 - 5.1e-11 42.4 0.0 8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PXF49101.1 - 1.4e-10 41.8 0.0 3.6e-10 40.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 PXF49101.1 - 0.004 16.7 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PXF49101.1 - 0.0047 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 PXF49101.1 - 0.017 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 PXF49101.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PsbJ PF01788.17 PXF49101.1 - 0.032 14.1 1.1 0.058 13.3 1.1 1.4 1 0 0 1 1 1 0 PsbJ GCD14 PF08704.10 PXF49101.1 - 0.056 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ATP-synt_ab PF00006.25 PXF49102.1 - 4.1e-60 203.1 0.0 8.7e-60 202.0 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PXF49102.1 - 8.3e-24 83.9 0.7 1.6e-23 83.0 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 PXF49102.1 - 0.039 13.3 0.3 0.084 12.2 0.3 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 PXF49102.1 - 0.076 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 PXF49102.1 - 0.17 12.2 1.0 0.59 10.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 PXF49102.1 - 0.22 10.6 0.1 0.39 9.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain SAM_1 PF00536.30 PXF49103.1 - 6.1e-16 58.6 0.0 9.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PXF49103.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF202 PF02656.15 PXF49103.1 - 1e-10 41.9 7.4 2.6e-10 40.6 3.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3611 PF12263.8 PXF49103.1 - 0.024 14.5 0.8 0.035 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) MHYT PF03707.16 PXF49103.1 - 0.44 10.7 0.2 0.44 10.7 0.2 2.7 2 1 1 3 3 3 0 Bacterial signalling protein N terminal repeat SRTM1 PF15872.5 PXF49103.1 - 2.4 8.3 5.4 1.2 9.3 0.9 2.4 1 1 2 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 RNase_PH PF01138.21 PXF49104.1 - 5.4e-27 94.9 0.0 9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF49104.1 - 4.7e-09 36.1 0.1 9.4e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 KRAB PF01352.27 PXF49104.1 - 0.025 14.2 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 KRAB box Histone PF00125.24 PXF49105.1 - 9e-21 74.6 0.0 1.1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF49105.1 - 7e-07 29.4 0.1 1.7e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PXF49105.1 - 0.0077 16.7 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 PXF49105.1 - 0.052 13.6 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 PXF49106.1 - 1.4e-19 69.5 0.2 2.5e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PXF49106.1 - 3.3e-17 63.1 0.0 4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF49106.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2_2 PF12756.7 PXF49107.1 - 1e-22 80.3 2.9 4.9e-16 58.9 0.0 3.2 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PXF49107.1 - 1.9e-16 59.8 1.4 9.9e-06 25.7 0.5 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PXF49107.1 - 5e-14 52.1 6.3 1.5e-06 28.4 0.7 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PXF49107.1 - 7.4e-09 35.7 3.2 0.016 16.0 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 PXF49107.1 - 6.4e-06 26.0 9.4 0.0046 16.9 0.8 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PXF49107.1 - 2.9e-05 24.3 7.2 0.25 11.9 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type AKAP95 PF04988.12 PXF49107.1 - 0.0094 16.2 0.5 2.2 8.5 0.1 2.5 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_11 PF16622.5 PXF49107.1 - 0.057 13.2 3.9 6.7 6.6 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2083 PF09856.9 PXF49107.1 - 0.19 11.6 3.0 1.2 9.0 0.5 2.4 2 0 0 2 2 2 0 Predicted transcriptional regulator (DUF2083) C1_1 PF00130.22 PXF49107.1 - 0.44 10.5 2.4 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_C2H2_ZHX PF18387.1 PXF49107.1 - 3.5 7.3 5.8 3.7 7.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LSD1 PF06943.12 PXF49107.1 - 8.9 6.3 7.9 0.48 10.3 1.0 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Peptidase_C14 PF00656.22 PXF49108.1 - 8.8e-43 147.0 0.0 1.2e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Oxidored_q2 PF00420.24 PXF49111.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Phage_integrase PF00589.22 PXF49111.1 - 0.026 14.3 0.1 0.078 12.8 0.1 1.8 1 1 0 1 1 1 0 Phage integrase family MAPEG PF01124.18 PXF49112.1 - 0.064 13.2 0.2 0.064 13.2 0.2 1.7 2 1 0 2 2 2 0 MAPEG family Ribonuc_L-PSP PF01042.21 PXF49114.1 - 1.3e-61 205.9 1.2 3.1e-36 124.1 0.9 2.2 2 0 0 2 2 2 2 Endoribonuclease L-PSP PQQ_3 PF13570.6 PXF49114.1 - 0.0038 17.7 1.9 1 9.9 0.2 2.6 2 0 0 2 2 2 2 PQQ-like domain BON PF04972.17 PXF49114.1 - 0.011 16.0 3.1 0.47 10.8 0.0 3.1 4 0 0 4 4 4 0 BON domain PapC_C PF13953.6 PXF49114.1 - 0.37 10.6 1.2 7.4 6.5 0.1 2.6 3 0 0 3 3 3 0 PapC C-terminal domain DEAD PF00270.29 PXF49115.1 - 2e-38 131.9 0.1 3.4e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF49115.1 - 1.2e-26 93.2 0.9 6.8e-25 87.6 0.4 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PXF49115.1 - 0.00098 18.5 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SMC_N PF02463.19 PXF49115.1 - 0.22 10.9 0.5 0.41 10.0 0.5 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TPT PF03151.16 PXF49116.1 - 8e-06 25.4 7.8 9.5e-06 25.2 7.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family CitMHS PF03600.16 PXF49116.1 - 0.0078 15.4 3.2 0.0093 15.2 3.2 1.1 1 0 0 1 1 1 1 Citrate transporter DUF2070 PF09843.9 PXF49116.1 - 0.0097 14.3 7.4 0.012 14.0 7.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) EamA PF00892.20 PXF49116.1 - 0.43 10.7 14.7 3.1 8.0 0.5 2.5 2 1 1 3 3 3 0 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 PXF49116.1 - 6.2 6.7 13.2 0.21 11.4 2.1 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling MFS_2 PF13347.6 PXF49117.1 - 2.1e-11 43.0 3.4 2.1e-11 43.0 3.4 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 PXF49117.1 - 0.005 15.7 0.7 0.044 12.6 0.0 2.4 2 1 0 2 2 2 1 MFS_1 like family Chloroa_b-bind PF00504.21 PXF49118.1 - 2.4e-34 119.2 0.0 2.8e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF3437 PF11919.8 PXF49119.1 - 0.035 14.0 0.2 0.084 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) IL4 PF00727.18 PXF49119.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Interleukin 4 PHO4 PF01384.20 PXF49120.1 - 4.1e-104 348.3 34.9 5.3e-104 347.9 34.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 PXF49120.1 - 0.00012 21.8 0.3 0.13 12.1 0.1 2.9 2 0 0 2 2 2 2 IclR helix-turn-helix domain Fumarate_red_D PF02313.17 PXF49120.1 - 5.3 7.2 17.2 1.7 8.8 0.6 4.1 3 1 0 4 4 4 0 Fumarate reductase subunit D JmjN PF02375.17 PXF49121.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 jmjN domain JmjC PF02373.22 PXF49122.1 - 5.7e-05 23.5 0.1 0.00016 22.0 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Glyco_hydro_19 PF00182.19 PXF49124.1 - 4.3e-10 39.9 0.0 9.6e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Chitinase class I Dynein_light PF01221.18 PXF49125.1 - 6.9e-35 119.2 0.0 9e-35 118.9 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FH2 PF02181.23 PXF49126.1 - 1.9e-67 228.0 13.3 8.2e-62 209.5 10.1 2.4 2 0 0 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.9 PXF49126.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ten1_2 PF15490.6 PXF49127.1 - 4.8e-22 77.9 0.0 5.8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ras PF00071.22 PXF49128.1 - 1.2e-36 125.7 0.0 1.5e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF49128.1 - 1.4e-08 34.9 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF49128.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PXF49128.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NARP1 PF12569.8 PXF49129.1 - 2.1e-149 498.7 0.0 9.7e-141 470.2 0.0 3.4 3 1 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 PXF49129.1 - 2.9e-10 39.4 27.5 0.00021 21.2 1.6 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49129.1 - 1.1e-09 38.8 32.5 0.057 14.1 2.8 7.5 8 1 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49129.1 - 7.8e-09 35.9 22.5 0.087 13.3 2.7 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49129.1 - 9.8e-08 31.6 12.3 0.0016 18.5 0.6 7.3 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49129.1 - 1.1e-06 28.9 33.4 0.4 11.6 0.1 9.3 8 2 1 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF49129.1 - 3.9e-06 27.0 13.0 0.29 11.4 1.0 5.9 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PXF49129.1 - 1.7e-05 24.8 5.5 7 7.3 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF49129.1 - 5.6e-05 22.8 11.4 0.037 13.9 1.4 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49129.1 - 7.2e-05 22.5 19.1 0.076 13.1 0.7 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 PXF49129.1 - 9.9e-05 22.6 17.6 2.7 8.9 0.5 6.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49129.1 - 0.00011 22.3 18.7 0.63 10.2 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49129.1 - 0.00027 21.1 21.6 0.9 9.9 0.2 6.8 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 PXF49129.1 - 0.00093 18.5 7.7 0.034 13.4 4.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49129.1 - 0.002 17.8 1.9 0.002 17.8 1.9 4.9 8 0 0 8 8 7 1 TPR repeat TPR_6 PF13174.6 PXF49129.1 - 0.14 12.9 18.5 14 6.5 0.0 7.4 10 0 0 10 10 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PXF49129.1 - 6.9 6.7 8.9 14 5.7 0.6 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat GATA PF00320.27 PXF49130.1 - 9e-15 54.0 9.9 1.4e-14 53.3 9.9 1.3 1 0 0 1 1 1 1 GATA zinc finger DUF2318 PF10080.9 PXF49130.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.7 PXF49130.1 - 0.042 13.9 2.8 0.24 11.5 1.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 PXF49130.1 - 0.066 12.7 0.6 0.12 11.9 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 PXF49130.1 - 0.15 11.8 1.5 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.11 PXF49130.1 - 0.16 11.9 1.3 0.28 11.1 1.3 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain tRNA-synt_1g PF09334.11 PXF49131.1 - 3.1e-94 315.9 1.2 3.5e-61 207.1 0.0 3.1 1 1 2 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF49131.1 - 4.5e-24 84.7 0.0 7e-13 47.7 0.0 2.8 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PXF49131.1 - 4.5e-14 52.5 0.0 2.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 PXF49131.1 - 4e-05 23.6 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA CRISPR_Cse1 PF09481.10 PXF49131.1 - 0.42 9.6 4.7 0.23 10.5 2.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) NIF PF03031.18 PXF49132.1 - 7.3e-24 84.3 0.0 2e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 PXF49132.1 - 0.0005 19.9 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 PXF49132.1 - 0.035 14.5 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PH_8 PF15409.6 PXF49134.1 - 2e-05 24.7 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 PXF49134.1 - 0.00042 20.8 0.1 0.00094 19.7 0.0 1.6 2 0 0 2 2 2 1 PH domain BPL_N PF09825.9 PXF49135.1 - 1.7e-39 136.0 0.0 2.1e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal DJ-1_PfpI PF01965.24 PXF49135.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Prefoldin_2 PF01920.20 PXF49136.1 - 7.7e-18 64.4 4.2 9.9e-18 64.0 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 PXF49136.1 - 0.00037 20.5 6.5 0.0046 17.0 2.5 2.2 2 0 0 2 2 2 1 DASH complex subunit Dad3 Prefoldin PF02996.17 PXF49136.1 - 0.0033 17.3 5.7 0.024 14.5 0.4 2.2 2 0 0 2 2 2 1 Prefoldin subunit ADIP PF11559.8 PXF49136.1 - 0.0052 16.9 11.6 0.062 13.4 0.9 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 PXF49136.1 - 0.006 16.6 7.5 0.48 10.5 0.4 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein 4HB_MCP_1 PF12729.7 PXF49136.1 - 0.0066 16.0 2.7 0.015 14.8 2.7 1.5 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction ArsR PF09824.9 PXF49136.1 - 0.0083 15.7 1.3 0.14 11.8 0.1 2.0 1 1 1 2 2 2 1 ArsR transcriptional regulator BLOC1_2 PF10046.9 PXF49136.1 - 0.009 16.3 6.5 0.077 13.3 0.4 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoU PF01895.19 PXF49136.1 - 0.01 16.2 0.6 0.53 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoU domain DUF724 PF05266.14 PXF49136.1 - 0.014 15.3 3.0 0.019 14.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.12 PXF49136.1 - 0.023 14.3 7.7 0.69 9.4 0.4 2.1 2 0 0 2 2 2 0 PspA/IM30 family Cep57_CLD_2 PF14197.6 PXF49136.1 - 0.024 14.7 10.1 0.34 11.0 0.2 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 PhoU_div PF01865.16 PXF49136.1 - 0.024 14.0 0.3 0.07 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF47 vATP-synt_AC39 PF01992.16 PXF49136.1 - 0.026 14.0 0.1 0.03 13.8 0.1 1.0 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit DUF948 PF06103.11 PXF49136.1 - 0.036 14.3 2.1 0.43 10.9 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 PXF49136.1 - 0.038 13.6 4.8 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 Snf7 Syntaxin_2 PF14523.6 PXF49136.1 - 0.039 14.3 9.1 1.7 9.0 8.7 2.1 1 1 0 1 1 1 0 Syntaxin-like protein COG5 PF10392.9 PXF49136.1 - 0.04 14.1 8.3 1.1 9.4 0.6 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 betaPIX_CC PF16523.5 PXF49136.1 - 0.04 13.7 1.4 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 betaPIX coiled coil DASH_Spc19 PF08287.11 PXF49136.1 - 0.049 13.5 7.9 0.29 11.0 0.3 2.1 2 0 0 2 2 2 0 Spc19 Syntaxin-6_N PF09177.11 PXF49136.1 - 0.054 14.0 5.2 0.7 10.5 5.2 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 PXF49136.1 - 0.057 13.4 8.0 0.64 10.1 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 PXF49136.1 - 0.061 14.0 2.7 7.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Myb_DNA-bind_5 PF13873.6 PXF49136.1 - 0.073 13.1 1.0 5.4 7.2 0.1 2.7 1 1 1 3 3 2 0 Myb/SANT-like DNA-binding domain DivIC PF04977.15 PXF49136.1 - 0.084 12.7 7.8 0.79 9.5 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator AKNA PF12443.8 PXF49136.1 - 0.086 13.5 6.8 2.4 8.8 2.3 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor T4SS PF07996.11 PXF49136.1 - 0.097 13.1 12.8 2 8.8 12.8 2.4 1 1 0 1 1 1 0 Type IV secretion system proteins LPP PF04728.13 PXF49136.1 - 0.099 13.0 5.5 1 9.8 0.5 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ApoO PF09769.9 PXF49136.1 - 0.12 12.3 1.7 0.96 9.4 1.7 1.9 1 1 0 1 1 1 0 Apolipoprotein O TssO PF17561.2 PXF49136.1 - 0.13 12.3 3.5 0.13 12.3 0.6 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF4795 PF16043.5 PXF49136.1 - 0.14 11.7 5.2 2.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Mod_r PF07200.13 PXF49136.1 - 0.15 12.2 10.0 0.27 11.3 0.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 PXF49136.1 - 0.15 12.1 3.4 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.10 PXF49136.1 - 0.17 12.1 6.0 2.6 8.2 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.6 PXF49136.1 - 0.17 11.8 3.5 0.48 10.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) bZIP_2 PF07716.15 PXF49136.1 - 0.17 12.0 6.4 0.86 9.7 0.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dam1 PF08653.10 PXF49136.1 - 0.19 11.6 1.2 0.6 10.0 0.1 2.1 2 1 0 2 2 2 0 DASH complex subunit Dam1 TMF_TATA_bd PF12325.8 PXF49136.1 - 0.19 11.9 8.6 0.28 11.4 0.6 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 PXF49136.1 - 0.3 11.1 9.2 9 6.3 9.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.13 PXF49136.1 - 0.33 10.9 5.1 0.28 11.1 0.4 2.1 2 0 0 2 2 2 0 Sec20 JAKMIP_CC3 PF16034.5 PXF49136.1 - 0.41 10.6 9.1 3 7.8 3.3 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain APG6_N PF17675.1 PXF49136.1 - 0.43 11.1 9.7 11 6.5 9.7 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 PXF49136.1 - 0.44 8.5 4.2 0.83 7.5 3.4 1.7 1 1 0 1 1 1 0 Prominin DUF812 PF05667.11 PXF49136.1 - 0.46 9.3 8.8 0.16 10.8 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF883 PF05957.13 PXF49136.1 - 0.51 11.0 6.1 4 8.1 0.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.12 PXF49136.1 - 0.53 10.3 6.1 0.64 10.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 PXF49136.1 - 0.58 10.6 9.3 2.1 8.9 0.3 2.4 2 1 0 2 2 2 0 Cell division protein ZapB Fzo_mitofusin PF04799.13 PXF49136.1 - 0.66 9.5 7.4 1.1 8.8 1.1 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF2508 PF10704.9 PXF49136.1 - 0.75 10.0 5.5 0.85 9.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) ABC_tran_Xtn PF12848.7 PXF49136.1 - 0.85 9.7 8.3 3.2 7.8 1.9 2.1 1 1 1 2 2 2 0 ABC transporter OmpH PF03938.14 PXF49136.1 - 0.95 9.8 9.7 2.9 8.2 1.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FliD_C PF07195.12 PXF49136.1 - 1.1 8.6 5.7 2.7 7.4 5.7 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Csm1_N PF18504.1 PXF49136.1 - 1.8 9.0 8.8 2.4 8.6 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 PXF49136.1 - 2 7.9 7.1 2.3 7.7 7.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 PXF49136.1 - 2.2 6.8 5.1 8.2 4.9 5.1 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 PXF49136.1 - 2.3 7.5 7.0 2.9 7.1 7.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein YlqD PF11068.8 PXF49136.1 - 2.8 8.3 13.1 7.4 7.0 4.3 2.1 1 1 1 2 2 2 0 YlqD protein LMBR1 PF04791.16 PXF49136.1 - 2.9 6.7 4.6 3.3 6.5 4.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FliJ PF02050.16 PXF49136.1 - 2.9 8.1 14.5 0.97 9.7 4.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 PXF49136.1 - 4.5 6.5 9.1 26 4.0 9.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 PXF49136.1 - 6.7 7.1 9.0 20 5.6 3.3 2.6 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 JmjC PF02373.22 PXF49137.1 - 1.1e-32 112.9 0.4 1.7e-32 112.2 0.1 1.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase Terminase_5 PF06056.12 PXF49138.1 - 0.14 12.1 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) CHCH PF06747.13 PXF49139.1 - 0.00024 21.2 17.0 0.0034 17.5 8.6 2.6 2 1 0 2 2 2 2 CHCH domain CX9C PF16860.5 PXF49139.1 - 0.0021 18.0 11.1 0.28 11.2 0.2 2.4 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 PXF49139.1 - 0.0028 17.6 14.4 0.003 17.5 4.2 2.9 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 PXF49139.1 - 0.0069 16.7 12.4 0.62 10.4 7.6 2.9 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 PXF49139.1 - 0.48 10.7 9.1 0.91 9.8 6.9 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 PXF49139.1 - 1.8 8.8 10.2 1.1 9.5 2.4 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Peptidase_S41 PF03572.18 PXF49140.1 - 7.4e-32 110.2 0.0 1.1e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 PXF49140.1 - 2.2e-08 34.3 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PXF49140.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PXF49140.1 - 1.3e-06 28.7 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain SPARC_Ca_bdg PF10591.9 PXF49140.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Phasin_2 PF09361.10 PXF49141.1 - 0.036 14.3 11.1 8.4 6.7 6.8 2.0 1 1 0 1 1 1 0 Phasin protein DUF883 PF05957.13 PXF49141.1 - 0.075 13.6 14.6 0.3 11.7 6.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PXF49141.1 - 1.5 9.4 19.5 1.2e+03 0.1 19.5 2.7 1 1 0 1 1 1 0 YtxH-like protein HSP9_HSP12 PF04119.12 PXF49141.1 - 3.4 8.1 14.1 10 6.6 4.7 3.6 1 1 3 4 4 4 0 Heat shock protein 9/12 Pkinase PF00069.25 PXF49142.1 - 2.2e-56 191.2 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49142.1 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49142.1 - 7.4e-07 28.8 0.0 9.9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF49142.1 - 7.3e-06 25.2 0.0 1.8e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF49142.1 - 2.5e-05 23.7 0.1 4.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF49142.1 - 0.00048 20.1 1.2 0.017 15.0 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF49142.1 - 0.009 14.8 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Vma12 PF11712.8 PXF49143.1 - 5.4e-12 46.0 0.1 8.4e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2937 PF11157.8 PXF49143.1 - 0.046 13.4 4.2 0.047 13.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) ATPase_gene1 PF09527.10 PXF49143.1 - 0.074 13.2 3.0 0.1 12.7 3.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Ctr PF04145.15 PXF49143.1 - 0.078 13.6 0.2 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family Wzz PF02706.15 PXF49143.1 - 0.13 12.5 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Chain length determinant protein DUF5367 PF17329.2 PXF49143.1 - 0.19 11.9 1.2 0.29 11.3 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5367) SPT_ssu-like PF11779.8 PXF49144.1 - 7.9e-16 57.4 2.4 9.8e-16 57.1 2.4 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like CTD_bind PF04818.13 PXF49145.1 - 2.2e-07 31.6 0.0 5.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 PXF49145.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain Chromo PF00385.24 PXF49150.1 - 2.6e-05 24.1 0.8 3.6e-05 23.6 0.8 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.32 PXF49152.1 - 2.8e-11 43.8 0.8 4e-05 24.3 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF49152.1 - 1.7e-06 28.2 0.1 0.09 13.1 0.0 3.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PXF49152.1 - 0.0087 15.7 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 PQQ-like domain PEPCK_N PF17297.2 PXF49152.1 - 0.041 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain PQQ PF01011.21 PXF49152.1 - 0.14 12.1 0.0 24 5.1 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat WD40_like PF17005.5 PXF49152.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain zf-MYND PF01753.18 PXF49153.1 - 8.4e-09 35.4 9.4 2e-08 34.2 9.1 1.7 1 1 1 2 2 2 2 MYND finger zf-Mss51 PF13824.6 PXF49153.1 - 0.26 11.4 2.0 0.63 10.2 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Cyclin PF08613.11 PXF49154.1 - 4.6e-14 53.1 0.4 7.5e-14 52.4 0.4 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF49154.1 - 4.7e-06 26.4 0.5 1e-05 25.3 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 PXF49156.1 - 1.6e-16 60.2 41.9 1.6e-16 60.2 41.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.11 PXF49157.1 - 4e-12 46.8 0.1 6.3e-12 46.2 0.1 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF49157.1 - 5.6e-05 22.9 0.0 9.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LuxT_C PF18285.1 PXF49158.1 - 0.037 14.5 0.2 0.33 11.5 0.0 2.6 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain RRP7 PF12923.7 PXF49162.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RVT_1 PF00078.27 PXF49163.1 - 1.3e-33 116.4 0.0 5.7e-33 114.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PXF49163.1 - 3.2e-15 56.0 0.4 1.3e-14 54.1 0.4 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PXF49163.1 - 0.017 14.7 0.4 0.078 12.5 0.1 2.2 3 0 0 3 3 3 0 Endonuclease/Exonuclease/phosphatase family PCIF1_WW PF12237.8 PXF49165.1 - 0.059 13.0 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain APH PF01636.23 PXF49166.1 - 8.4e-06 25.9 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49166.1 - 0.0012 18.2 0.0 0.0038 16.6 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49166.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 CDP-OH_P_transf PF01066.21 PXF49168.1 - 1.3e-11 45.1 0.5 1.3e-11 45.1 0.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase LSM PF01423.22 PXF49170.1 - 2.6e-06 27.0 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF49170.1 - 0.01 16.0 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain NopRA1 PF16201.5 PXF49171.1 - 3.3e-21 75.8 1.2 1.4e-20 73.7 1.2 2.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 PXF49171.1 - 0.0032 16.9 8.8 0.016 14.6 2.8 3.2 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal Trypsin PF00089.26 PXF49172.1 - 3.6e-39 134.8 0.7 5.7e-39 134.2 0.0 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PXF49172.1 - 1.6e-07 32.3 0.1 1.6e-07 32.3 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain AnfG_VnfG PF03139.15 PXF49174.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit EF-hand_1 PF00036.32 PXF49175.1 - 1.1e-41 137.3 10.2 1.9e-10 39.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PXF49175.1 - 2.2e-34 117.7 3.4 6.6e-17 61.7 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PXF49175.1 - 4.3e-31 104.2 9.2 1.3e-09 37.2 0.1 5.2 4 2 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 PXF49175.1 - 3.3e-30 103.7 11.0 4.4e-15 55.3 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PXF49175.1 - 5e-29 98.5 9.9 1.2e-07 30.9 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PXF49175.1 - 3.3e-16 59.4 0.1 1.4e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PXF49175.1 - 5.3e-09 36.0 0.7 0.00097 19.1 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PXF49175.1 - 7.3e-09 35.9 0.0 0.00031 21.0 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PXF49175.1 - 9.1e-08 32.0 1.4 0.01 15.8 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 PXF49175.1 - 5.9e-06 27.1 0.0 0.0014 19.4 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 PXF49175.1 - 0.00014 22.0 4.2 0.027 14.7 0.3 2.7 1 1 1 2 2 2 2 Dockerin type I domain TerB PF05099.13 PXF49175.1 - 0.00033 20.6 0.4 0.12 12.3 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 PXF49175.1 - 0.00056 20.2 0.2 0.04 14.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 PXF49175.1 - 0.0033 17.4 0.5 1.7 8.6 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 PXF49175.1 - 0.0041 17.5 1.0 1.3 9.4 0.5 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 FGAR-AT_linker PF18072.1 PXF49175.1 - 0.007 16.9 0.4 0.66 10.6 0.0 2.5 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF1456 PF07308.13 PXF49175.1 - 0.015 15.7 0.3 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF327 PF03885.13 PXF49175.1 - 0.015 15.2 0.9 4 7.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF327) GPHH PF16905.5 PXF49175.1 - 0.019 14.7 0.0 1.4 8.8 0.0 3.2 4 0 0 4 4 4 0 Voltage-dependent L-type calcium channel, IQ-associated VbhA PF18495.1 PXF49175.1 - 0.034 14.0 0.1 27 4.7 0.0 3.9 4 0 0 4 4 4 0 Antitoxin VbhA DUF5580 PF17743.1 PXF49175.1 - 0.037 12.6 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 PXF49175.1 - 0.04 13.8 0.6 0.14 12.1 0.6 1.9 1 0 0 1 1 1 0 EF hand SurA_N_2 PF13623.6 PXF49175.1 - 0.053 13.4 1.4 0.55 10.1 0.3 2.3 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N_3 PF13624.6 PXF49175.1 - 0.069 12.9 0.9 0.81 9.5 0.4 2.1 1 1 1 2 2 2 0 SurA N-terminal domain RloB PF13707.6 PXF49175.1 - 0.08 13.1 0.7 1 9.5 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein DUF4497 PF14924.6 PXF49175.1 - 0.089 13.3 0.0 19 5.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) Phage_tail_S PF05069.13 PXF49175.1 - 0.11 12.3 0.3 2.3 8.1 0.1 2.1 1 1 1 2 2 2 0 Phage virion morphogenesis family PMBR PF09373.10 PXF49175.1 - 0.16 12.2 0.1 40 4.6 0.0 3.1 2 0 0 2 2 2 0 Pseudomurein-binding repeat Mst1_SARAH PF11629.8 PXF49175.1 - 0.34 11.0 2.9 1.7 8.8 0.8 2.8 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Glycos_trans_3N PF02885.17 PXF49175.1 - 0.74 9.7 4.5 2.4 8.1 0.1 3.5 2 2 1 3 3 3 0 Glycosyl transferase family, helical bundle domain Skp1 PF01466.19 PXF49175.1 - 1.1 9.4 5.3 2.7 8.2 0.2 3.0 3 0 0 3 3 3 0 Skp1 family, dimerisation domain DUF533 PF04391.12 PXF49175.1 - 2.2 7.9 5.4 17 4.9 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF533) Sad1_UNC PF07738.13 PXF49176.1 - 1.2e-15 57.7 0.0 3.2e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RNase_Zc3h12a PF11977.8 PXF49178.1 - 3.2e-20 72.5 0.0 5.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 PXF49178.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Protein-only RNase P DUF5615 PF18480.1 PXF49178.1 - 0.22 11.3 1.1 0.77 9.6 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) Exo_endo_phos PF03372.23 PXF49179.1 - 3.7e-11 43.0 0.0 4e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 PXF49179.1 - 2.1e-07 30.9 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TsaE PF02367.17 PXF49180.1 - 4.6e-27 94.5 0.0 8.2e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PXF49180.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 PXF49180.1 - 0.0033 17.7 0.0 0.0086 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PXF49180.1 - 0.0042 17.5 0.0 0.005 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 PXF49180.1 - 0.047 13.9 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 PXF49180.1 - 0.054 13.9 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PXF49180.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 PXF49180.1 - 0.079 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 PXF49180.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PXF49180.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 PXF49180.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 PXF49180.1 - 0.16 12.2 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PXF49180.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 PXF49180.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_14 PF13428.6 PXF49182.1 - 2e-20 71.7 24.2 0.012 16.3 0.0 11.8 7 3 5 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49182.1 - 2.5e-16 59.9 0.0 0.0014 19.1 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49182.1 - 3.3e-12 46.8 8.1 0.022 15.4 0.1 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 PXF49182.1 - 3.6e-09 37.1 18.8 8.1e-06 26.0 4.7 5.6 3 2 2 6 6 6 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 PXF49182.1 - 6e-09 35.7 0.9 0.051 14.0 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat HAT PF02184.16 PXF49182.1 - 8.6e-09 35.2 72.2 3.2e-07 30.2 0.2 13.5 13 1 0 13 13 12 3 HAT (Half-A-TPR) repeat TPR_15 PF13429.6 PXF49182.1 - 2.5e-07 30.2 23.2 0.00011 21.5 0.3 6.3 1 1 5 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49182.1 - 8.9e-07 28.6 10.1 31 5.0 0.0 9.0 11 0 0 11 11 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PXF49182.1 - 1.7e-06 28.0 22.4 0.82 9.7 0.5 7.1 6 2 1 7 7 7 4 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 PXF49182.1 - 2.9e-05 23.9 3.3 4.1 7.9 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 PXF49182.1 - 0.0011 19.4 16.0 0.76 10.5 0.0 8.1 10 0 0 10 10 8 1 Tetratricopeptide repeat PIN_12 PF16289.5 PXF49182.1 - 0.028 14.9 4.2 0.06 13.8 0.4 3.0 2 1 1 3 3 3 0 PIN domain FGAR-AT_linker PF18072.1 PXF49182.1 - 0.08 13.5 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain 5-FTHF_cyc-lig PF01812.20 PXF49182.1 - 0.13 12.1 0.2 0.39 10.5 0.2 1.8 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family SNAP PF14938.6 PXF49182.1 - 0.18 11.2 8.4 6.7 6.0 0.2 4.5 4 2 1 5 5 5 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 PXF49182.1 - 0.43 11.0 8.0 2.9 8.3 0.2 4.1 3 2 1 4 4 4 0 Bacterial transcriptional activator domain PilJ PF13675.6 PXF49182.1 - 2.8 8.0 8.5 3.9 7.5 0.2 4.2 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term U3_assoc_6 PF08640.11 PXF49182.1 - 6.7 6.9 22.6 1.2 9.3 0.5 7.0 5 3 3 8 8 8 0 U3 small nucleolar RNA-associated protein 6 Atx10homo_assoc PF09759.9 PXF49183.1 - 0.076 13.0 0.1 5.5 7.1 0.0 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF327 PF03885.13 PXF49183.1 - 0.17 11.9 0.3 0.33 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) YIF1 PF03878.15 PXF49185.1 - 7.2e-65 218.8 0.3 1e-64 218.4 0.3 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 PXF49185.1 - 0.0014 18.4 1.1 0.0031 17.2 1.1 1.5 1 0 0 1 1 1 1 Yip1 domain Fucokinase PF07959.12 PXF49186.1 - 2.8e-06 26.5 0.6 0.011 14.6 0.3 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep PF00132.24 PXF49186.1 - 9.8e-05 21.9 6.4 0.0021 17.7 4.9 2.8 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Peptidase_C37 PF05416.12 PXF49186.1 - 0.019 13.5 0.2 0.027 13.0 0.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Cnd2 PF05786.14 PXF49186.1 - 3.3 6.2 16.2 4.9 5.7 16.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF3381 PF11861.8 PXF49186.1 - 6.6 6.5 17.1 12 5.7 17.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) W2 PF02020.18 PXF49187.1 - 5.9e-16 58.4 0.9 1.2e-15 57.3 0.9 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1615 PF07759.12 PXF49187.1 - 0.0046 16.2 2.0 0.13 11.5 1.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1615) RNase_PH PF01138.21 PXF49188.1 - 8.3e-21 74.9 0.2 2.2e-14 54.1 0.0 2.7 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PXF49188.1 - 4.8e-08 32.9 0.1 0.00098 19.1 0.1 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 PXF49188.1 - 0.00036 20.8 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DHR-2 PF06920.13 PXF49188.1 - 0.18 10.4 1.3 0.23 10.1 0.8 1.4 2 0 0 2 2 2 0 Dock homology region 2 Acatn PF13000.7 PXF49191.1 - 1.5e-105 353.9 14.4 4.2e-83 279.7 5.8 3.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DHHA2 PF02833.14 PXF49192.1 - 8.7e-15 55.2 0.0 2.7e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 PXF49192.1 - 8.9e-13 48.4 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 DHH family Glyco_hydro_85 PF03644.13 PXF49193.1 - 1.7e-82 277.2 0.0 2.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 APH PF01636.23 PXF49194.1 - 1.8e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49194.1 - 0.0036 16.7 0.0 0.011 15.0 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49194.1 - 0.089 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 APH PF01636.23 PXF49196.1 - 8.3e-06 25.9 0.1 1.5e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49196.1 - 0.0015 17.9 0.0 0.0049 16.2 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49196.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 APH PF01636.23 PXF49198.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49198.1 - 0.0016 17.8 0.0 0.0049 16.2 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49198.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 APH PF01636.23 PXF49199.1 - 5.2e-06 26.6 0.1 9.8e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49199.1 - 0.0018 17.7 0.0 0.0051 16.2 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49199.1 - 0.12 12.5 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 APH PF01636.23 PXF49201.1 - 7.8e-06 26.0 0.1 1.9e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49201.1 - 0.0014 18.0 0.0 0.0042 16.4 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49201.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 APH PF01636.23 PXF49202.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49202.1 - 0.0016 17.8 0.0 0.0046 16.3 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49202.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 GDP_Man_Dehyd PF16363.5 PXF49203.1 - 4e-36 125.1 0.0 4.9e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PXF49203.1 - 4e-28 98.5 0.0 5.1e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PXF49203.1 - 1.2e-14 54.2 0.0 4.8e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PXF49203.1 - 1.2e-12 47.6 0.0 2.1e-11 43.5 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 PXF49203.1 - 1.6e-10 40.6 0.0 2.1e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PXF49203.1 - 2.1e-08 33.6 0.0 2.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF49203.1 - 0.00014 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF49203.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family Glu_dehyd_C PF16912.5 PXF49203.1 - 0.21 11.1 0.0 0.48 9.9 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Acetyltransf_10 PF13673.7 PXF49204.1 - 1.9e-13 50.4 0.0 3.2e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF49204.1 - 3.6e-08 33.7 0.0 3.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 PXF49204.1 - 3.8e-07 30.3 0.0 6.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_1 PF00583.25 PXF49204.1 - 7.5e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyoxalase_4 PF13669.6 PXF49204.1 - 0.00045 20.5 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PanZ PF12568.8 PXF49204.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 PXF49204.1 - 0.13 12.3 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 PXF49204.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HPP PF04982.13 PXF49205.1 - 0.35 11.1 8.0 0.23 11.7 0.4 2.5 1 1 0 2 2 2 0 HPP family DUF3488 PF11992.8 PXF49205.1 - 1.3 7.9 12.2 0.69 8.8 10.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) Tmemb_14 PF03647.13 PXF49205.1 - 2.3 9.0 7.6 4.1 8.2 0.7 2.8 2 1 0 2 2 2 0 Transmembrane proteins 14C EP400_N PF15790.5 PXF49206.1 - 0.12 11.2 2.2 0.11 11.3 2.2 1.0 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Glyco_hydro_47 PF01532.20 PXF49207.1 - 4.6e-67 226.9 0.0 6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RNase_T PF00929.24 PXF49209.1 - 1.3e-20 74.5 0.0 1.9e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 PXF49209.1 - 0.02 14.9 0.0 0.61 10.1 0.0 2.2 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 PXF49209.1 - 0.13 11.9 0.0 4 7.1 0.0 2.2 2 0 0 2 2 2 0 3'-5' exonuclease RPE65 PF03055.15 PXF49211.1 - 2.3e-86 290.8 0.0 2.9e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein NAM-associated PF14303.6 PXF49212.1 - 0.34 11.6 8.5 0.45 11.2 8.5 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain APH PF01636.23 PXF49214.1 - 4e-06 26.9 0.3 8e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 PXF49214.1 - 0.0017 17.7 0.0 0.0049 16.2 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase baeRF_family8 PF18851.1 PXF49214.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 8 Choline_kinase PF01633.20 PXF49214.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBP_BcsG PF11658.8 PXF49216.1 - 0.067 11.6 0.1 0.086 11.2 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Aldedh PF00171.22 PXF49217.1 - 1.1e-83 281.3 0.0 1.4e-83 281.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lactonase PF10282.9 PXF49218.1 - 4.6e-39 134.7 0.0 5.9e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Indigoidine_A PF04227.12 PXF49219.1 - 1.8e-106 355.8 2.3 2.4e-106 355.4 2.3 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 PXF49219.1 - 8.3e-37 127.1 1.0 1.7e-36 126.1 1.0 1.5 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Band_7 PF01145.25 PXF49220.1 - 7.3e-27 94.5 0.3 7.3e-27 94.5 0.3 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 PXF49220.1 - 1.3e-07 31.5 0.1 2.6e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 PXF49220.1 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pex14_N PF04695.13 PXF49220.1 - 0.0039 17.8 1.8 0.0039 17.8 1.8 4.2 4 1 1 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Gram_pos_anchor PF00746.21 PXF49220.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NAP PF00956.18 PXF49222.1 - 3.1e-54 184.0 2.3 3.4e-50 170.7 0.1 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) SpoU_methylase PF00588.19 PXF49223.1 - 4.4e-18 65.8 0.0 7.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family NIR_SIR PF01077.22 PXF49225.1 - 2.8e-57 192.7 0.0 2.3e-41 140.9 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 PXF49225.1 - 3e-33 113.5 0.0 1.8e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Tho2 PF11262.8 PXF49226.1 - 3.3e-61 207.1 0.3 7.3e-61 206.0 0.3 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 PXF49226.1 - 3.1e-38 131.9 14.3 1.7e-19 69.9 0.0 4.0 4 1 0 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 PXF49226.1 - 4e-15 55.6 0.0 2.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PAM2 PF07145.15 PXF49226.1 - 0.026 14.2 0.2 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region YflT PF11181.8 PXF49226.1 - 0.051 14.1 0.0 3 8.4 0.1 2.7 2 0 0 2 2 2 0 Heat induced stress protein YflT AMP-binding PF00501.28 PXF49227.1 - 3.6e-35 121.4 0.1 5e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PXF49227.1 - 4.1e-19 69.3 3.8 8.9e-19 68.3 3.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UbiA PF01040.18 PXF49229.1 - 7.9e-19 67.9 17.7 1.1e-18 67.5 17.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1430 PF07242.11 PXF49229.1 - 7.5 6.9 7.9 0.39 11.0 0.4 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) NAD_binding_10 PF13460.6 PXF49230.1 - 1.7e-31 109.5 0.0 9.2e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 PXF49230.1 - 7.3e-17 61.7 0.0 1.5e-14 54.2 0.0 2.8 2 1 0 2 2 2 2 NmrA-like family CIA30 PF08547.12 PXF49230.1 - 4.1e-16 59.4 0.0 6.1e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Epimerase PF01370.21 PXF49230.1 - 2.2e-05 24.1 0.1 4.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NSs PF11073.8 PXF49230.1 - 0.0043 16.6 0.1 0.009 15.5 0.1 1.5 1 0 0 1 1 1 1 Rift valley fever virus non structural protein (NSs) like 3Beta_HSD PF01073.19 PXF49230.1 - 0.0058 15.7 0.2 0.0087 15.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TRAM_LAG1_CLN8 PF03798.16 PXF49232.1 - 5.3e-06 26.3 11.7 3.2e-05 23.8 11.8 2.0 1 1 0 1 1 1 1 TLC domain PALP PF00291.25 PXF49233.1 - 1.8e-64 218.0 2.2 2.1e-64 217.8 2.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEX11 PF05648.14 PXF49235.1 - 2.5e-35 122.0 5.0 2.9e-35 121.8 5.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) BRI3BP PF14965.6 PXF49235.1 - 0.039 13.5 0.2 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Negative regulator of p53/TP53 TB2_DP1_HVA22 PF03134.19 PXF49237.1 - 6e-08 32.5 0.5 6e-08 32.5 0.5 2.3 2 0 0 2 2 2 1 TB2/DP1, HVA22 family LD_cluster3 PF18180.1 PXF49237.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SLOG cluster3 family Caveolin PF01146.17 PXF49237.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.0 3 0 0 3 3 3 0 Caveolin Ribosomal_L14e PF01929.17 PXF49238.1 - 3.1e-25 88.5 1.3 4.3e-25 88.0 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 DUF3767 PF12597.8 PXF49239.1 - 1.3e-14 53.9 0.1 1.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SVIP PF15811.5 PXF49239.1 - 0.00074 19.9 1.7 0.0013 19.2 1.7 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein AMP-binding PF00501.28 PXF49241.1 - 3.9e-50 170.7 0.0 3.9e-50 170.7 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme SARS_lipid_bind PF09399.10 PXF49241.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 SARS lipid binding protein DUF3138 PF11336.8 PXF49241.1 - 0.46 9.0 4.9 0.71 8.4 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Oxidored_molyb PF00174.19 PXF49245.1 - 6.3e-51 172.4 0.2 1.2e-50 171.5 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PXF49245.1 - 2.5e-28 98.8 0.7 2.5e-28 98.8 0.7 2.5 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 PXF49245.1 - 8.9e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EF-hand_1 PF00036.32 PXF49246.1 - 1.3e-09 36.9 1.3 0.00051 19.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF49246.1 - 2.6e-09 36.2 0.6 0.00013 21.6 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PXF49246.1 - 3.2e-07 30.7 0.8 6.2e-07 29.8 0.8 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PXF49246.1 - 1.3e-06 27.6 1.1 0.004 16.6 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PXF49246.1 - 3.3e-05 23.6 2.5 0.11 12.4 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PXF49246.1 - 0.033 14.5 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 PXF49246.1 - 0.074 12.9 0.5 2.8 7.9 0.3 2.2 1 1 1 2 2 2 0 EF hand EF-hand_7 PF13499.6 PXF49247.1 - 4.7e-10 39.8 0.1 6e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PXF49247.1 - 7.8e-09 34.5 0.1 0.0029 17.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF49247.1 - 6.5e-08 31.9 0.3 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PXF49247.1 - 1.4e-05 24.4 0.1 0.07 12.7 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 PXF49247.1 - 0.0024 17.7 0.6 1.5 8.8 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PXF49247.1 - 0.0028 17.5 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PXF49247.1 - 0.026 14.9 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Actin PF00022.19 PXF49248.1 - 6.7e-97 324.7 0.0 1e-95 320.8 0.0 1.9 1 1 0 1 1 1 1 Actin DSS1_SEM1 PF05160.13 PXF49249.1 - 2.1e-14 53.3 15.5 2.8e-14 52.9 15.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 PXF49249.1 - 0.00091 19.1 1.9 0.00091 19.1 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) Pyr_excise PF03013.14 PXF49249.1 - 0.074 13.0 0.6 0.091 12.7 0.6 1.1 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Peptidase_M16_C PF05193.21 PXF49250.1 - 1.3e-25 90.4 0.0 2.1e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PXF49250.1 - 1.3e-24 86.9 0.0 3.6e-24 85.4 0.0 1.8 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) LRR_4 PF12799.7 PXF49251.1 - 0.05 14.0 11.1 10 6.7 0.1 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) DUF4218 PF13960.6 PXF49252.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) SnoaL_2 PF12680.7 PXF49256.1 - 1.8e-11 44.6 0.0 7.1e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain STAS_2 PF13466.6 PXF49256.1 - 0.037 14.4 0.4 0.063 13.6 0.4 1.4 1 0 0 1 1 1 0 STAS domain YtxH PF12732.7 PXF49257.1 - 0.00049 20.6 16.9 0.051 14.1 4.5 2.8 1 1 1 2 2 2 2 YtxH-like protein Borrelia_P83 PF05262.11 PXF49257.1 - 0.036 12.6 17.6 0.046 12.2 17.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ApoLp-III PF07464.11 PXF49257.1 - 0.18 11.9 6.5 0.27 11.3 4.7 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 PXF49257.1 - 0.22 12.1 32.1 14 6.3 14.8 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ly49 PF08391.10 PXF49257.1 - 0.41 11.0 1.7 0.69 10.3 1.7 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region BAF1_ABF1 PF04684.13 PXF49257.1 - 0.42 9.6 12.2 0.53 9.3 12.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Exonuc_VII_L PF02601.15 PXF49257.1 - 0.57 9.7 16.0 0.81 9.2 16.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 PXF49257.1 - 0.69 9.3 14.6 0.93 8.9 14.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 ApoO PF09769.9 PXF49257.1 - 0.76 9.7 4.9 5.4 7.0 2.4 2.5 1 1 1 2 2 2 0 Apolipoprotein O Asp-B-Hydro_N PF05279.11 PXF49257.1 - 1.5 8.8 13.3 2.3 8.2 13.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPF0242 PF06785.11 PXF49257.1 - 3.1 7.9 9.3 4.5 7.3 8.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 PXF49257.1 - 3.2 7.5 29.6 4.9 6.9 29.6 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CCDC71L PF15374.6 PXF49257.1 - 5.2 6.2 17.7 7.6 5.7 17.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PCI PF01399.27 PXF49258.1 - 1.5e-18 67.2 0.1 4.7e-18 65.6 0.1 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 PXF49258.1 - 2.6e-13 49.8 0.7 2.6e-13 49.8 0.7 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Paf67 PF10255.9 PXF49258.1 - 0.0099 14.9 0.9 0.038 13.0 0.5 1.9 1 1 1 2 2 2 1 RNA polymerase I-associated factor PAF67 CSN8_PSD8_EIF3K PF10075.9 PXF49258.1 - 0.071 13.1 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family MgtE_N PF03448.17 PXF49258.1 - 0.073 13.7 6.4 0.35 11.5 1.2 3.0 2 1 0 2 2 2 0 MgtE intracellular N domain Alkyl_sulf_dimr PF14863.6 PXF49258.1 - 0.29 11.6 2.7 2.2 8.7 0.3 2.9 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TraB PF01963.17 PXF49258.1 - 0.78 9.6 8.6 0.051 13.5 0.7 2.2 2 0 0 2 2 2 0 TraB family ERp29 PF07749.12 PXF49258.1 - 1.9 9.4 7.6 0.75 10.7 0.3 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain 53-BP1_Tudor PF09038.10 PXF49259.1 - 0.029 14.3 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor JAB PF01398.21 PXF49260.1 - 3.8e-13 49.5 3.0 1.2e-12 47.8 3.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 PXF49260.1 - 0.13 12.3 0.4 0.89 9.6 0.0 2.3 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0172) LETM1 PF07766.13 PXF49261.1 - 1.8e-85 286.5 0.1 1.8e-85 286.5 0.1 2.5 2 0 0 2 2 2 1 LETM1-like protein EF-hand_1 PF00036.32 PXF49261.1 - 3.4e-09 35.6 2.2 0.00072 18.9 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PXF49261.1 - 2.5e-08 33.2 0.9 0.0012 18.6 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PXF49261.1 - 2.1e-06 28.1 4.9 0.002 18.6 0.4 3.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PXF49261.1 - 1.5e-05 24.2 6.3 9.5e-05 21.7 0.4 3.2 3 0 0 3 3 3 1 EF hand Bacillus_HBL PF05791.11 PXF49261.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Dockerin_1 PF00404.18 PXF49261.1 - 0.11 12.7 4.0 7.5 6.8 0.9 2.9 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_8 PF13833.6 PXF49261.1 - 0.12 12.2 1.3 3.4 7.6 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PXF49261.1 - 0.2 12.0 5.8 0.81 10.0 0.2 3.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TERB2 PF15101.6 PXF49261.1 - 1.6 8.8 7.6 0.65 10.0 1.5 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 TPR_1 PF00515.28 PXF49262.1 - 0.00024 20.8 5.8 0.09 12.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49262.1 - 0.0011 19.2 8.7 0.19 12.1 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49262.1 - 0.01 15.9 13.9 2.5 8.4 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 PXF49262.1 - 0.013 15.8 0.0 0.5 10.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF49262.1 - 3.8 8.4 8.4 55 4.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TMEM18 PF14770.6 PXF49263.1 - 1.9e-29 102.0 1.0 2.6e-29 101.6 1.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF805 PF05656.14 PXF49263.1 - 0.0019 18.6 1.8 0.0026 18.2 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF805) DUF4834 PF16118.5 PXF49263.1 - 0.82 10.7 0.0 0.82 10.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3611 PF12263.8 PXF49264.1 - 8.2e-36 123.6 11.4 1.1e-35 123.1 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) SUR7 PF06687.12 PXF49264.1 - 0.0021 17.7 0.1 0.0046 16.6 0.1 1.7 1 1 0 1 1 1 1 SUR7/PalI family UL42 PF17638.2 PXF49264.1 - 0.024 14.6 0.6 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 HCMV UL42 KIAA1430 PF13879.6 PXF49264.1 - 0.035 14.8 0.0 0.053 14.3 0.0 1.2 1 0 0 1 1 1 0 KIAA1430 homologue FKBP_C PF00254.28 PXF49265.1 - 1.6e-44 150.2 0.0 1.9e-30 105.0 0.0 3.4 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PXF49265.1 - 2.1e-18 65.3 0.1 1.1e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49265.1 - 1.7e-15 55.8 0.0 0.00059 19.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49265.1 - 1.6e-10 40.3 0.1 0.00038 20.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49265.1 - 3.7e-09 36.1 0.2 0.0035 17.0 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 PXF49265.1 - 2.2e-07 31.1 0.0 0.035 14.4 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49265.1 - 7.1e-05 23.3 0.0 13 6.9 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49265.1 - 0.00033 20.8 0.0 0.038 14.4 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49265.1 - 0.00086 19.8 0.0 0.15 12.6 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49265.1 - 0.00089 19.1 0.0 0.55 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49265.1 - 0.0041 17.2 0.0 0.018 15.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PXF49265.1 - 0.011 16.3 0.1 1.2 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat IPI_T4 PF11634.8 PXF49265.1 - 0.028 14.4 1.0 3.5 7.7 0.0 3.3 3 0 0 3 3 3 0 Nuclease inhibitor from bacteriophage T4 Fis1_TPR_C PF14853.6 PXF49265.1 - 0.031 14.3 1.4 1.2 9.3 0.3 2.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 PXF49265.1 - 0.065 13.9 0.0 0.36 11.5 0.0 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Longin PF13774.6 PXF49266.1 - 1.7e-18 66.4 0.1 3.5e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PXF49266.1 - 1.7e-16 59.8 2.2 1.7e-16 59.8 2.2 1.9 2 0 0 2 2 2 1 Synaptobrevin LMBR1 PF04791.16 PXF49266.1 - 0.021 13.8 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 PXF49266.1 - 0.043 12.7 6.1 0.25 10.2 3.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TetR_C_37 PF18665.1 PXF49266.1 - 0.052 14.2 0.3 0.59 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YgaB PF14182.6 PXF49266.1 - 0.083 13.3 1.7 0.16 12.4 0.5 2.1 2 1 0 2 2 2 0 YgaB-like protein PKK PF12474.8 PXF49266.1 - 0.14 12.3 6.6 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Polo kinase kinase Pkinase PF00069.25 PXF49267.1 - 2.3e-76 256.6 0.1 3.2e-76 256.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49267.1 - 1.6e-40 139.1 0.0 2.6e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49267.1 - 1.1e-05 24.9 0.0 2.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF49267.1 - 0.00016 21.1 0.2 0.00029 20.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF49267.1 - 0.00068 19.3 0.1 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PXF49267.1 - 0.0009 19.2 0.0 0.0032 17.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF49267.1 - 0.0092 15.6 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Cofilin_ADF PF00241.20 PXF49268.1 - 6.5e-32 109.9 0.1 7.4e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein S-methyl_trans PF02574.16 PXF49270.1 - 6.1e-50 170.5 0.1 7.6e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Arabinose_Iso_C PF11762.8 PXF49270.1 - 0.11 12.3 0.1 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain Actin PF00022.19 PXF49271.1 - 8.6e-139 462.6 0.0 2.8e-138 461.0 0.0 1.7 1 1 0 1 1 1 1 Actin GCV_T PF01571.21 PXF49272.1 - 2.9e-87 292.3 0.0 3.8e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PXF49272.1 - 4.3e-16 58.6 0.0 1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HHH_9 PF17674.1 PXF49273.1 - 0.041 14.8 0.1 0.095 13.6 0.1 1.6 1 0 0 1 1 1 0 HHH domain Mg_trans_NIPA PF05653.14 PXF49276.1 - 6.5e-29 101.0 7.2 9e-29 100.5 7.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 PXF49276.1 - 0.011 15.9 2.4 0.011 15.9 2.4 3.1 2 2 0 2 2 2 0 EamA-like transporter family Phlebovirus_G1 PF07243.11 PXF49276.1 - 0.014 13.8 1.9 0.02 13.3 1.9 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Ras PF00071.22 PXF49277.1 - 2e-60 203.1 0.1 2.4e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF49277.1 - 2.6e-32 111.6 0.0 4.6e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PXF49277.1 - 2.4e-12 46.6 0.0 2.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PXF49277.1 - 2.6e-05 24.3 0.0 5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PXF49277.1 - 0.00055 19.9 0.1 0.65 9.9 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 PXF49277.1 - 0.0009 18.8 0.0 0.0057 16.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PXF49277.1 - 0.0068 16.7 0.0 0.37 11.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 PXF49277.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 PXF49277.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DNA_pol_E_B PF04042.16 PXF49277.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B HEAT PF02985.22 PXF49278.1 - 4.1e-22 76.4 16.9 0.019 15.2 0.0 10.5 11 0 0 11 11 10 6 HEAT repeat HEAT_EZ PF13513.6 PXF49278.1 - 3.5e-20 72.1 16.3 5.1e-08 33.3 0.0 10.0 9 2 2 11 11 10 5 HEAT-like repeat HEAT_2 PF13646.6 PXF49278.1 - 1.2e-15 57.7 2.6 0.0012 19.2 0.0 7.2 4 3 5 9 9 8 5 HEAT repeats Cnd1 PF12717.7 PXF49278.1 - 3.9e-11 43.3 0.8 0.00045 20.3 0.0 4.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PXF49278.1 - 6.1e-10 39.6 0.0 0.002 18.7 0.0 5.5 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 PXF49278.1 - 5e-08 32.7 0.1 5e-07 29.5 0.1 2.8 2 1 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 PXF49278.1 - 1.9e-07 30.9 0.3 0.27 10.8 0.0 4.5 4 0 0 4 4 4 3 CLASP N terminal DUF3437 PF11919.8 PXF49278.1 - 3.2e-05 23.8 0.3 1 9.3 0.0 4.5 5 1 0 5 5 4 1 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 PXF49278.1 - 3.4e-05 22.6 4.8 0.97 7.9 0.5 4.5 3 1 1 4 4 4 3 Adaptin N terminal region DRIM PF07539.12 PXF49278.1 - 3.9e-05 22.2 1.3 0.00012 20.5 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis DNA_alkylation PF08713.11 PXF49278.1 - 0.00019 21.2 0.0 0.034 13.9 0.0 2.4 1 1 1 2 2 2 2 DNA alkylation repair enzyme Arm PF00514.23 PXF49278.1 - 0.00086 19.3 10.8 24 5.1 0.0 7.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat MOR2-PAG1_N PF14222.6 PXF49278.1 - 0.00096 18.2 2.1 0.016 14.1 0.2 2.7 2 2 0 2 2 2 1 Cell morphogenesis N-terminal Dopey_N PF04118.14 PXF49278.1 - 0.0019 17.4 0.2 0.04 13.0 0.0 2.9 3 0 0 3 3 3 1 Dopey, N-terminal Tti2 PF10521.9 PXF49278.1 - 0.0085 15.7 6.4 0.25 10.8 0.2 4.6 4 1 1 5 5 5 1 Tti2 family Gcn1_N PF12074.8 PXF49278.1 - 0.018 14.4 0.0 0.095 12.0 0.0 2.1 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal UNC45-central PF11701.8 PXF49278.1 - 0.029 14.3 2.7 14 5.6 0.0 4.6 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central Ecm29 PF13001.7 PXF49278.1 - 0.042 12.5 0.3 5.8 5.5 0.0 3.4 3 1 1 4 4 4 0 Proteasome stabiliser Sec7_N PF12783.7 PXF49278.1 - 0.46 10.4 2.6 0.88 9.5 0.2 2.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal adh_short PF00106.25 PXF49280.1 - 4.1e-27 94.9 0.0 3e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PXF49280.1 - 6.3e-15 55.4 0.0 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3446 PF11928.8 PXF49280.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Lipase_GDSL_2 PF13472.6 PXF49281.1 - 2e-10 41.3 0.0 4.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PXF49281.1 - 1.2e-05 25.4 0.0 6.5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 PXF49281.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribonuc_L-PSP PF01042.21 PXF49284.1 - 1.8e-13 50.5 0.0 2.4e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pkinase PF00069.25 PXF49285.1 - 4.2e-65 219.7 0.0 7.4e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49285.1 - 1.2e-38 132.9 0.0 2.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PXF49285.1 - 0.00014 21.5 0.3 0.0026 17.4 0.1 2.5 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 PXF49285.1 - 0.00021 21.3 3.1 0.00058 19.8 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PXF49285.1 - 0.00022 20.3 1.5 0.00022 20.3 1.5 1.7 2 0 0 2 2 2 1 Haspin like kinase domain NFACT-R_1 PF05670.13 PXF49286.1 - 0.00025 21.6 0.0 0.00082 20.0 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 PXF49287.1 - 4.3e-18 66.0 0.1 5.5e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 PXF49287.1 - 0.00015 21.9 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain GFO_IDH_MocA PF01408.22 PXF49289.1 - 4.1e-25 88.9 0.2 9.1e-25 87.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF49289.1 - 3.4e-11 43.2 0.0 7.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 PXF49289.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 PXF49289.1 - 0.0051 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PXF49289.1 - 0.02 15.5 1.0 0.037 14.6 0.2 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 PXF49289.1 - 0.027 14.6 0.4 0.072 13.2 0.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Peripla_BP_1 PF00532.21 PXF49289.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Rossmann-like PF10727.9 PXF49289.1 - 0.074 12.9 1.2 0.12 12.2 0.4 1.8 2 0 0 2 2 2 0 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 PXF49289.1 - 0.11 12.8 0.3 0.64 10.3 0.2 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 PXF49289.1 - 0.18 11.8 0.7 2 8.5 0.2 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cactin_mid PF10312.9 PXF49290.1 - 0.22 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin CENP-T_C PF15511.6 PXF49291.1 - 1.3e-08 34.9 0.1 1.6e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PXF49291.1 - 0.001 19.4 0.1 0.0017 18.7 0.1 1.5 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 PXF49291.1 - 0.0012 19.2 0.2 0.0015 18.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF49291.1 - 0.002 18.4 0.1 0.003 17.8 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 PXF49291.1 - 0.0033 17.5 0.2 0.0046 17.1 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 PXF49291.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PXF49291.1 - 0.082 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated DNA_primase_S PF01896.19 PXF49292.1 - 5.7e-48 163.3 0.4 7.4e-48 162.9 0.4 1.2 1 0 0 1 1 1 1 DNA primase small subunit Abhydrolase_9_N PF15420.6 PXF49293.1 - 0.021 14.8 1.2 0.024 14.6 1.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SCAMP PF04144.13 PXF49293.1 - 0.044 14.1 3.0 0.046 14.0 3.0 1.1 1 0 0 1 1 1 0 SCAMP family DUF2929 PF11151.8 PXF49293.1 - 4.7 7.6 8.0 5.1 7.5 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) zf-H2C2_2 PF13465.6 PXF49294.1 - 3.6e-21 74.6 29.5 9.1e-08 32.2 0.1 6.3 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 PXF49294.1 - 1.7e-16 59.7 41.0 0.0016 18.8 0.9 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF49294.1 - 9.9e-11 41.5 41.4 0.013 16.2 3.5 5.8 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 PXF49294.1 - 1.5e-06 28.9 18.5 0.29 11.8 0.8 4.4 1 1 3 4 4 4 4 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 PXF49294.1 - 0.00024 21.0 22.9 0.043 13.8 0.5 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PXF49294.1 - 0.00032 20.9 1.8 0.00032 20.9 1.8 3.5 2 1 2 4 4 4 1 C2H2-type zinc ribbon RNA_POL_M_15KD PF02150.16 PXF49294.1 - 0.0045 16.8 7.3 0.15 12.0 0.0 4.0 5 0 0 5 5 5 1 RNA polymerases M/15 Kd subunit zf-C2H2_2 PF12756.7 PXF49294.1 - 0.0053 17.1 19.4 0.86 10.0 0.0 4.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PXF49294.1 - 0.0062 16.9 28.0 3.9 8.0 0.2 5.9 6 0 0 6 6 6 2 Zinc-finger of C2H2 type C1_1 PF00130.22 PXF49294.1 - 0.026 14.4 17.8 0.41 10.6 1.7 3.4 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 PXF49294.1 - 0.067 13.6 14.3 16 6.1 1.3 4.4 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 PXF49294.1 - 0.32 11.1 12.8 2 8.6 0.7 3.7 3 1 0 3 3 3 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 PXF49294.1 - 0.36 10.6 22.2 1 9.2 1.3 5.2 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 PXF49294.1 - 0.6 10.5 26.5 4.6 7.7 0.7 5.9 6 1 0 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.6 PXF49294.1 - 0.95 9.3 5.8 21 5.0 0.1 3.8 2 2 1 4 4 4 0 Domain of unknown function (DUF4187) zf-AN1 PF01428.16 PXF49294.1 - 1.3 9.2 14.9 19 5.5 0.1 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger zf-HYPF PF07503.12 PXF49294.1 - 1.4 8.7 0.1 1.4 8.7 0.1 4.1 5 0 0 5 5 5 0 HypF finger zf-ISL3 PF14690.6 PXF49294.1 - 2.7 8.7 23.6 0.56 10.9 1.0 4.6 5 0 0 5 5 5 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-MYST PF17772.1 PXF49294.1 - 3.1 7.5 6.4 10 5.8 0.0 3.7 3 1 1 4 4 4 0 MYST family zinc finger domain DZR PF12773.7 PXF49294.1 - 3.6 7.7 17.4 1.2e+04 -3.6 17.4 3.2 1 1 0 1 1 0 0 Double zinc ribbon Mito_carr PF00153.27 PXF49295.1 - 4.9e-62 205.9 0.4 1.8e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16_C PF05193.21 PXF49296.1 - 6.1e-09 36.1 0.0 0.00037 20.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PXF49296.1 - 6.4e-06 26.2 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 PXF49296.1 - 0.049 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M16C associated DUF563 PF04577.14 PXF49297.1 - 1.5e-08 35.1 0.0 3.5e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) RSN1_TM PF13967.6 PXF49297.1 - 0.042 13.6 0.6 2.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport NS3 PF17530.2 PXF49297.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Non-structural protein NS3 zf-RING_11 PF17123.5 PXF49298.1 - 1.2e-09 37.7 5.5 1.2e-09 37.7 5.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 PXF49298.1 - 2.4e-09 37.4 14.6 2.4e-09 37.4 14.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PXF49298.1 - 2.8e-06 27.1 9.3 5.3e-06 26.2 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF49298.1 - 5e-05 23.5 14.0 0.00018 21.7 14.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF49298.1 - 6.2e-05 22.8 10.2 0.00012 21.9 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PXF49298.1 - 0.0005 19.6 7.7 0.00079 19.0 7.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PXF49298.1 - 0.00065 19.7 7.6 0.0015 18.5 7.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF49298.1 - 0.031 14.1 13.0 0.06 13.2 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PXF49298.1 - 0.052 13.6 4.2 0.1 12.7 4.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PXF49298.1 - 0.081 12.9 12.3 0.15 12.0 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF4381 PF14316.6 PXF49298.1 - 0.27 11.5 4.0 0.22 11.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-RING-like PF08746.11 PXF49298.1 - 0.35 11.2 9.3 0.7 10.3 9.3 1.5 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.25 PXF49299.1 - 4.7e-30 104.8 0.0 6.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49299.1 - 1.7e-11 43.9 0.0 2.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF49299.1 - 0.0012 18.9 0.1 0.07 13.0 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PXF49299.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Cupin_3 PF05899.12 PXF49300.1 - 2.4e-25 88.0 0.0 3.7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 PXF49300.1 - 2.8e-07 30.4 0.0 3.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 PXF49300.1 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 PXF49300.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Cupin AMPK1_CBM PF16561.5 PXF49301.1 - 1.4e-28 98.9 0.1 2.4e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 PXF49301.1 - 0.0058 16.9 0.2 0.023 14.9 0.0 2.1 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Nop10p PF04135.12 PXF49302.1 - 1.8e-19 69.5 0.4 1.9e-19 69.4 0.4 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NifU_N PF01592.16 PXF49303.1 - 1.5e-54 183.5 0.2 2e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain RRM_1 PF00076.22 PXF49305.1 - 6.7e-18 64.3 0.0 1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PXF49305.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NIF PF03031.18 PXF49307.1 - 6e-54 182.0 0.1 1.2e-53 181.1 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Prefoldin PF02996.17 PXF49308.1 - 1.8e-30 105.3 0.2 2.7e-30 104.8 0.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 PXF49308.1 - 0.0008 19.3 0.1 0.074 13.0 0.0 2.3 2 0 0 2 2 2 1 Prefoldin subunit ATP-synt_D PF01813.17 PXF49308.1 - 0.021 14.7 0.3 0.035 13.9 0.3 1.4 1 1 0 1 1 1 0 ATP synthase subunit D HR1 PF02185.16 PXF49308.1 - 0.038 14.1 1.8 0.047 13.8 0.1 2.1 2 1 0 2 2 2 0 Hr1 repeat Laminin_II PF06009.12 PXF49308.1 - 0.069 13.2 5.3 1.1 9.3 0.9 2.2 2 0 0 2 2 2 0 Laminin Domain II CCDC-167 PF15188.6 PXF49308.1 - 0.11 12.8 0.6 1.4 9.3 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Uds1 PF15456.6 PXF49308.1 - 0.11 12.6 4.5 0.37 10.9 3.0 2.0 1 1 1 2 2 2 0 Up-regulated During Septation CCDC144C PF14915.6 PXF49308.1 - 0.12 11.5 3.6 3.5 6.7 0.1 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Sec7 PF01369.20 PXF49309.1 - 1.4e-58 197.6 0.0 2.3e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PXF49309.1 - 5.3e-06 26.4 0.3 0.0024 17.8 0.0 4.0 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PXF49309.1 - 0.0063 16.3 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Ferritin PF00210.24 PXF49309.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain CRM1_C PF08767.11 PXF49310.1 - 9.4e-100 333.9 4.7 1.1e-99 333.6 0.8 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 PXF49310.1 - 4.5e-37 127.4 1.3 6.1e-36 123.7 0.9 3.2 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 PXF49310.1 - 3.3e-35 119.5 1.8 1.3e-34 117.7 1.8 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 PXF49310.1 - 1e-27 96.0 1.3 1e-27 96.0 1.3 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 PXF49310.1 - 7.5e-15 54.2 0.6 1.8e-14 52.9 0.6 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 PXF49310.1 - 2.3e-11 43.4 0.2 2.3e-11 43.4 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Sulfotransfer_1 PF00685.27 PXF49311.1 - 8.6e-21 74.6 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PXF49311.1 - 7e-06 26.6 0.0 0.0095 16.3 0.0 2.6 1 1 0 2 2 2 2 Sulfotransferase family DDE_Tnp_4 PF13359.6 PXF49312.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 PXF49312.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease RNA_pol_Rpb5_C PF01191.19 PXF49314.1 - 1.1e-31 108.5 0.2 3.5e-31 106.9 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 PXF49314.1 - 2.3e-12 47.3 0.4 3.6e-12 46.7 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 PXF49314.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 Restriction endonuclease PTB PF08416.13 PXF49314.1 - 0.028 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain Clathrin PF00637.20 PXF49315.1 - 7.9e-160 525.1 4.1 9.1e-26 90.4 0.0 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 PXF49315.1 - 6.5e-25 86.2 0.1 2.6e-08 33.8 0.0 6.6 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 PXF49315.1 - 1.1e-22 79.6 0.1 6.7e-22 77.2 0.0 2.5 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 PXF49315.1 - 9.6e-07 28.1 1.2 1.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 PXF49315.1 - 0.00064 20.3 9.4 14 6.8 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49315.1 - 0.0089 16.0 6.9 4.4 7.6 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Mic1 PF07035.12 PXF49315.1 - 0.019 14.7 3.2 0.31 10.7 0.3 3.6 4 0 0 4 4 4 0 Colon cancer-associated protein Mic1-like TPR_8 PF13181.6 PXF49315.1 - 0.019 15.1 0.0 85 3.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49315.1 - 2.2 8.7 12.5 9.3 6.6 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF49315.1 - 5.7 7.3 9.7 8.5 6.7 0.1 5.4 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L7Ae PF01248.26 PXF49316.1 - 9.5e-18 63.7 0.0 1.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adenosine_kin PF04008.14 PXF49316.1 - 0.15 11.8 0.5 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Adenosine specific kinase Myb_DNA-binding PF00249.31 PXF49318.1 - 6.7e-10 39.0 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF49318.1 - 0.034 14.0 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PXF49318.1 - 0.037 14.3 0.1 0.069 13.4 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Metal_resist PF13801.6 PXF49318.1 - 6.8 6.9 11.4 0.46 10.7 0.3 3.4 3 0 0 3 3 3 0 Heavy-metal resistance Glycos_transf_1 PF00534.20 PXF49319.1 - 2.8e-33 114.9 0.0 4.5e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PXF49319.1 - 2.2e-27 96.1 0.8 4.2e-27 95.2 0.6 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 PXF49319.1 - 3.6e-27 95.4 0.0 1.3e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PXF49319.1 - 6.4e-20 72.2 0.3 1.8e-19 70.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 PXF49319.1 - 2.1e-15 57.1 1.9 2.1e-08 34.2 0.2 2.3 1 1 1 2 2 2 2 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 PXF49319.1 - 3.5e-06 27.3 0.0 7.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 PXF49319.1 - 0.00036 20.6 0.0 0.00093 19.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glycogen_syn PF05693.13 PXF49319.1 - 0.014 13.9 0.1 0.024 13.2 0.1 1.2 1 0 0 1 1 1 0 Glycogen synthase TPPII_N PF12583.8 PXF49319.1 - 0.018 15.7 3.8 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Ribul_P_3_epim PF00834.19 PXF49319.1 - 0.023 14.1 0.3 1.4 8.2 0.2 2.2 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family NAD_binding_10 PF13460.6 PXF49319.1 - 0.039 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding YjgF_endoribonc PF14588.6 PXF49321.1 - 0.046 13.9 0.0 0.051 13.7 0.0 1.0 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease IRF PF00605.17 PXF49321.1 - 0.14 12.4 0.0 1.9 8.8 0.0 1.9 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor PHO4 PF01384.20 PXF49323.1 - 6.9e-123 410.0 5.6 9.5e-123 409.5 5.6 1.2 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 PXF49323.1 - 0.021 14.6 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain LapA_dom PF06305.11 PXF49323.1 - 0.76 9.6 0.0 0.76 9.6 0.0 4.8 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain NfeD PF01957.18 PXF49323.1 - 2.2 8.7 4.7 44 4.5 0.0 3.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Sulfotransfer_2 PF03567.14 PXF49324.1 - 1.1e-05 25.5 0.1 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family zf-C3HC4_3 PF13920.6 PXF49325.1 - 6.1e-09 35.6 8.0 6.1e-09 35.6 8.0 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF49325.1 - 1.2e-05 25.1 6.9 1.2e-05 25.1 6.9 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PXF49325.1 - 0.016 15.1 8.8 0.016 15.1 8.8 3.9 3 1 1 4 4 4 0 zinc-RING finger domain ArfGap PF01412.18 PXF49325.1 - 0.23 11.5 7.3 0.63 10.1 7.3 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf YyzF PF14116.6 PXF49325.1 - 0.65 10.1 9.6 8.4 6.5 0.2 5.0 5 0 0 5 5 5 0 YyzF-like protein Peptidase_C50 PF03568.17 PXF49326.1 - 1e-57 196.1 6.0 1.8e-47 162.4 0.0 3.3 3 1 1 4 4 4 2 Peptidase family C50 CHAT PF12770.7 PXF49326.1 - 0.0019 17.6 0.1 0.11 11.9 0.0 2.8 2 0 0 2 2 2 1 CHAT domain TPR_19 PF14559.6 PXF49326.1 - 0.05 14.1 0.0 0.38 11.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Baculo_19 PF04798.12 PXF49326.1 - 0.13 11.9 0.1 0.37 10.5 0.1 1.8 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region EzrA PF06160.12 PXF49330.1 - 0.018 13.3 1.8 0.024 12.8 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF49330.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF49330.1 - 4.6 7.9 13.5 0.76 10.5 6.5 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain T4_baseplate PF12322.8 PXF49331.1 - 0.0027 17.2 0.1 0.0049 16.4 0.1 1.4 1 1 0 1 1 1 1 T4 bacteriophage base plate protein CpXC PF14353.6 PXF49331.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 CpXC protein Cob_adeno_trans PF01923.18 PXF49332.1 - 1.2e-57 194.6 0.0 1.5e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase PAC4 PF16093.5 PXF49332.1 - 0.022 14.9 0.1 0.089 13.0 0.1 1.9 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 Tropomyosin PF00261.20 PXF49332.1 - 0.14 11.5 0.5 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Tropomyosin DUF4248 PF14053.6 PXF49332.1 - 0.15 12.1 0.1 12 6.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4248) LapA_dom PF06305.11 PXF49333.1 - 0.005 16.6 0.1 0.017 14.9 0.1 1.9 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain CD34_antigen PF06365.12 PXF49333.1 - 0.012 15.2 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Mid2 PF04478.12 PXF49333.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Miga PF10265.9 PXF49333.1 - 0.03 13.3 0.2 0.055 12.5 0.2 1.4 1 0 0 1 1 1 0 Mitoguardin Rax2 PF12768.7 PXF49333.1 - 0.032 13.7 0.1 0.066 12.7 0.1 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 PXF49333.1 - 0.045 13.2 1.2 0.12 11.8 1.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NCU-G1 PF15065.6 PXF49333.1 - 0.046 12.7 1.6 0.6 9.0 1.3 2.3 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 TMEM154 PF15102.6 PXF49333.1 - 0.078 12.9 0.0 0.078 12.9 0.0 3.2 2 1 0 2 2 2 0 TMEM154 protein family m04gp34like PF12216.8 PXF49333.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.6 PXF49333.1 - 0.11 13.4 0.0 0.34 11.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trehalase PF01204.18 PXF49334.1 - 1.3e-119 400.4 0.0 1.5e-119 400.2 0.0 1.0 1 0 0 1 1 1 1 Trehalase Herpes_UL95 PF03038.14 PXF49334.1 - 0.0085 15.3 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 UL95 family DUF5623 PF18536.1 PXF49337.1 - 0.0084 16.4 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) DUF2390 PF09523.10 PXF49337.1 - 5.3 7.4 8.5 19 5.7 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) RVT_2 PF07727.14 PXF49341.1 - 0.03 14.0 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_zinc_N PF00107.26 PXF49342.1 - 2e-10 40.7 0.0 4.5e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pro_racemase PF05544.11 PXF49342.1 - 0.071 12.1 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Proline racemase Glu_dehyd_C PF16912.5 PXF49342.1 - 0.072 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Methyltransf_16 PF10294.9 PXF49343.1 - 1.5e-11 44.4 0.0 2.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 PXF49343.1 - 0.00032 20.5 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF49343.1 - 0.015 16.0 0.0 0.033 14.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49343.1 - 0.056 13.3 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CTP_transf_like PF01467.26 PXF49345.1 - 4.1e-07 30.3 0.0 9.2e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 PXF49345.1 - 0.052 13.4 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Atg14 PF10186.9 PXF49347.1 - 0.0037 16.4 3.0 0.0054 15.8 3.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 GPS2_interact PF15784.5 PXF49347.1 - 0.016 15.6 4.2 0.021 15.3 3.1 1.8 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Fez1 PF06818.15 PXF49347.1 - 0.022 15.2 6.3 0.034 14.6 6.3 1.3 1 0 0 1 1 1 0 Fez1 DUF3038 PF11237.8 PXF49347.1 - 0.027 14.5 1.7 0.054 13.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Spc7 PF08317.11 PXF49347.1 - 0.11 11.4 11.7 0.16 10.8 11.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_S30AE PF02482.19 PXF49347.1 - 0.2 12.5 2.3 11 6.9 0.5 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein OmpH PF03938.14 PXF49347.1 - 0.34 11.2 5.8 0.78 10.1 5.8 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 PXF49347.1 - 0.4 10.5 9.6 0.72 9.6 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 PXF49347.1 - 0.88 9.7 5.4 2 8.6 5.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 PXF49347.1 - 1.3 8.8 10.0 13 5.7 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator CENP-H PF05837.12 PXF49347.1 - 4.2 7.8 11.9 3.1 8.2 8.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF16 PF01519.16 PXF49347.1 - 5.3 7.6 7.5 3.1 8.3 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2070 PF09843.9 PXF49347.1 - 5.8 5.1 11.6 8.1 4.6 11.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YabA PF06156.13 PXF49347.1 - 6.6 7.4 8.8 4.2 8.0 3.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Radical_SAM PF04055.21 PXF49348.1 - 1.5e-17 64.5 0.0 3.3e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 PXF49348.1 - 0.04 14.0 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 HemN C-terminal domain MOZ_SAS PF01853.18 PXF49349.1 - 2.1e-47 161.1 0.0 1.9e-34 118.9 0.0 2.3 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 PXF49349.1 - 6.9e-17 60.8 0.2 1.3e-15 56.7 0.2 2.5 2 0 0 2 2 2 1 MYST family zinc finger domain IF2_N PF04760.15 PXF49349.1 - 0.022 14.5 0.2 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region S6OS1 PF15676.5 PXF49349.1 - 0.061 11.8 3.1 0.12 10.8 3.1 1.4 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family HTH_8 PF02954.19 PXF49349.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family ORC6 PF05460.13 PXF49349.1 - 6.6 5.9 15.5 14 4.8 15.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_S30 PF04758.14 PXF49350.1 - 2e-28 98.3 7.9 2.4e-28 98.1 7.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 ELFV_dehydrog_N PF02812.18 PXF49351.1 - 1.3e-58 196.5 0.0 2.4e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 PXF49351.1 - 1.6e-51 175.4 0.7 1.1e-47 162.8 0.1 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 PXF49351.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDC-P PF02347.16 PXF49352.1 - 5.1e-186 618.7 0.6 1.4e-172 574.4 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 PXF49352.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF5623 PF18536.1 PXF49354.1 - 0.0036 17.6 0.1 0.0062 16.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) DUF4933 PF16287.5 PXF49354.1 - 0.13 11.6 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4933) Aurora-A_bind PF09041.10 PXF49356.1 - 0.032 14.3 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Aurora-A binding SelB-wing_1 PF09105.10 PXF49357.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Sel1 PF08238.12 PXF49358.1 - 1.6e-13 50.8 13.9 5e-06 27.0 1.4 5.1 4 0 0 4 4 4 3 Sel1 repeat WD40 PF00400.32 PXF49359.1 - 1.7e-36 123.6 10.3 5.2e-08 33.4 0.2 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF49359.1 - 8.1e-13 48.5 0.7 0.003 17.8 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF49359.1 - 0.00044 20.2 0.0 0.015 15.2 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 PXF49359.1 - 0.0057 16.3 0.0 0.038 13.6 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Syntaxin_2 PF14523.6 PXF49360.1 - 0.028 14.8 0.6 0.042 14.2 0.6 1.3 1 0 0 1 1 1 0 Syntaxin-like protein HWE_HK PF07536.14 PXF49360.1 - 0.22 12.2 1.4 6.9 7.5 0.3 2.4 1 1 1 2 2 2 0 HWE histidine kinase Romo1 PF10247.9 PXF49361.1 - 2.4e-15 56.6 4.9 2.9e-15 56.4 4.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Sec6 PF06046.13 PXF49362.1 - 4e-26 91.5 0.8 7.1e-25 87.4 0.2 2.3 2 1 0 2 2 2 2 Exocyst complex component Sec6 Phos_pyr_kin PF08543.12 PXF49364.1 - 3.9e-15 55.9 0.0 5.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 PXF49364.1 - 4.8e-07 29.4 0.0 9.3e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 PXF49364.1 - 0.095 12.2 0.1 0.55 9.7 0.1 2.1 1 1 0 1 1 1 0 Carbohydrate kinase B56 PF01603.20 PXF49365.1 - 2.8e-155 517.4 0.8 3.2e-155 517.2 0.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) BRK PF07533.16 PXF49366.1 - 2e-21 75.4 4.0 4.3e-11 42.2 0.5 2.6 2 0 0 2 2 2 2 BRK domain SUIM_assoc PF16619.5 PXF49366.1 - 4.4e-05 23.5 1.5 4.4e-05 23.5 1.5 2.8 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF4692 PF15763.5 PXF49366.1 - 0.0014 19.2 0.3 0.0014 19.2 0.3 2.1 2 0 0 2 2 2 1 Regulator of human erythroid cell expansion (RHEX) Med3 PF11593.8 PXF49366.1 - 0.074 12.2 26.9 0.47 9.6 11.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ribosomal_S13_N PF08069.12 PXF49366.1 - 0.077 13.1 0.2 12 6.0 0.0 3.0 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain DUF4834 PF16118.5 PXF49366.1 - 6.1 7.9 6.9 1.4 10.0 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) 2OG-FeII_Oxy_2 PF13532.6 PXF49367.1 - 3.9e-13 50.0 0.2 1.8e-11 44.6 0.0 2.0 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily PRCC PF10253.9 PXF49369.1 - 3e-06 28.2 3.1 4.2e-06 27.7 3.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Runt PF00853.19 PXF49369.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Runt domain DUF5615 PF18480.1 PXF49369.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5615) EBP50_C PF09007.11 PXF49369.1 - 1.8 9.5 9.2 4.4 8.3 9.2 1.8 1 1 0 1 1 1 0 EBP50, C-terminal zf-RING_2 PF13639.6 PXF49370.1 - 8.4e-13 48.4 3.4 1.3e-12 47.8 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF49370.1 - 5.1e-09 35.7 0.1 5.1e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF49370.1 - 5.6e-09 35.7 2.6 8.7e-09 35.1 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF49370.1 - 1.6e-07 31.2 0.2 3.7e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PXF49370.1 - 1.7e-06 27.8 1.3 2.7e-06 27.1 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF49370.1 - 1.1e-05 25.7 5.5 3.2e-05 24.1 5.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PXF49370.1 - 1.3e-05 25.0 1.6 2.1e-05 24.3 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF49370.1 - 1.3e-05 24.9 2.4 2.5e-05 24.0 2.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PXF49370.1 - 2.8e-05 24.0 1.4 5e-05 23.2 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain NICE-3 PF07406.11 PXF49370.1 - 0.005 16.8 0.1 0.0077 16.2 0.1 1.3 1 0 0 1 1 1 1 NICE-3 protein DUF2970 PF11174.8 PXF49370.1 - 0.0088 15.9 1.9 0.015 15.1 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) TMEM154 PF15102.6 PXF49370.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family zf-C3HC4_4 PF15227.6 PXF49370.1 - 0.021 15.0 2.2 0.24 11.6 2.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Glycophorin_A PF01102.18 PXF49370.1 - 0.053 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A zf-RING_4 PF14570.6 PXF49370.1 - 0.055 13.3 4.1 0.3 10.9 4.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DNA_ligase_ZBD PF03119.16 PXF49370.1 - 0.066 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF3328 PF11807.8 PXF49370.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4492 PF14899.6 PXF49370.1 - 0.084 12.8 0.9 0.15 12.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Tmemb_9 PF05434.11 PXF49370.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 TMEM9 Gemini_mov PF01708.16 PXF49370.1 - 0.13 12.1 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF997 PF06196.12 PXF49370.1 - 0.16 12.0 4.1 0.12 12.4 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF1514 PF07438.11 PXF49370.1 - 4.9 7.1 8.5 9.5 6.2 8.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) Uma2 PF05685.12 PXF49375.1 - 2e-10 40.5 0.1 1e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 Putative restriction endonuclease Lsr2 PF11774.8 PXF49375.1 - 0.059 13.5 0.8 0.059 13.5 0.8 1.8 2 0 0 2 2 2 0 Lsr2 DAHP_synth_2 PF01474.16 PXF49376.1 - 1.3e-169 564.4 0.0 1.4e-169 564.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF3344 PF11824.8 PXF49377.1 - 7.7e-09 35.6 1.9 2.1e-08 34.1 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3344) Malectin PF11721.8 PXF49377.1 - 0.00042 20.4 0.0 0.00077 19.6 0.0 1.4 1 0 0 1 1 1 1 Malectin domain Homeodomain PF00046.29 PXF49379.1 - 9.2e-09 35.0 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Transcrip_act PF04949.13 PXF49380.1 - 2.8e-06 27.3 11.2 4.4e-06 26.6 11.2 1.3 1 0 0 1 1 1 1 Transcriptional activator Rab5-bind PF09311.11 PXF49380.1 - 0.00058 19.3 10.2 0.00084 18.8 10.2 1.2 1 0 0 1 1 1 1 Rabaptin-like protein WEMBL PF05701.11 PXF49380.1 - 0.0053 15.5 9.9 0.0065 15.2 9.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3584 PF12128.8 PXF49380.1 - 0.015 12.9 11.8 0.019 12.5 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bap31_Bap29_C PF18035.1 PXF49380.1 - 0.018 15.0 3.1 1.1 9.4 0.2 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Spc7 PF08317.11 PXF49380.1 - 0.042 12.7 14.7 0.059 12.2 14.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 PXF49380.1 - 0.047 13.0 16.3 0.071 12.4 15.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 PXF49380.1 - 0.052 12.6 9.7 0.075 12.1 9.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MatP_C PF17414.2 PXF49380.1 - 0.063 13.5 0.3 0.063 13.5 0.3 2.5 2 1 1 3 3 3 0 MatP C-terminal ribbon-helix-helix domain HIP1_clath_bdg PF16515.5 PXF49380.1 - 0.075 13.7 17.4 0.048 14.3 7.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 PXF49380.1 - 0.088 12.3 13.9 0.13 11.7 13.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 BicD PF09730.9 PXF49380.1 - 0.11 10.9 14.3 0.26 9.7 14.3 1.6 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FUSC PF04632.12 PXF49380.1 - 0.13 10.7 6.9 0.17 10.4 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S64 PF08192.11 PXF49380.1 - 0.14 10.6 3.9 0.16 10.5 3.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 APG6_N PF17675.1 PXF49380.1 - 0.45 11.1 17.7 0.1 13.1 14.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 PXF49380.1 - 0.5 10.4 8.2 0.44 10.6 5.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cluap1 PF10234.9 PXF49380.1 - 0.69 9.3 18.4 0.23 10.8 4.8 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4200 PF13863.6 PXF49380.1 - 1.3 9.4 17.7 3.6 8.0 17.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 PXF49380.1 - 1.5 6.6 6.1 1.9 6.3 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 PXF49380.1 - 2.7 7.5 12.7 4.1 7.0 12.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) FAM76 PF16046.5 PXF49380.1 - 3.4 7.0 12.2 1 8.7 4.4 2.0 1 1 1 2 2 2 0 FAM76 protein MerR-DNA-bind PF09278.11 PXF49380.1 - 3.7 8.1 17.5 0.37 11.4 7.0 3.0 3 0 0 3 3 3 0 MerR, DNA binding FlaC_arch PF05377.11 PXF49380.1 - 3.8 8.0 6.4 21 5.6 0.2 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 PXF49380.1 - 4.9 7.8 14.2 5.3 7.7 3.5 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 OmpH PF03938.14 PXF49380.1 - 5.3 7.4 20.0 40 4.5 20.0 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 PXF49380.1 - 5.6 5.5 10.6 9.4 4.7 10.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 PXF49380.1 - 7 6.8 25.4 0.36 11.0 9.9 2.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1515 PF07439.11 PXF49380.1 - 8.5 6.4 6.9 3 7.9 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) JIP_LZII PF16471.5 PXF49380.1 - 9.2 6.5 14.0 9.6 6.5 4.7 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Peptidase_M48_N PF16491.5 PXF49381.1 - 1.5e-48 165.1 4.5 1.5e-48 165.1 4.5 1.5 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 PXF49381.1 - 4.3e-20 72.3 0.0 7.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 PXF49381.1 - 0.00026 20.3 1.3 0.011 15.0 0.1 2.3 2 0 0 2 2 2 2 BlaR1 peptidase M56 DWNN PF08783.11 PXF49382.1 - 6.1e-23 80.9 0.2 1.2e-22 80.0 0.2 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 PXF49382.1 - 2.1e-09 37.0 5.4 4.1e-09 36.1 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PXF49382.1 - 0.00038 20.4 2.2 0.0008 19.4 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 PXF49382.1 - 0.0083 16.1 0.2 0.027 14.4 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-HC5HC2H PF13771.6 PXF49383.1 - 9.1e-10 38.7 9.1 9.1e-10 38.7 9.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PXF49383.1 - 7.3e-08 32.5 8.9 2.1e-07 31.1 6.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 PXF49383.1 - 0.16 11.9 4.1 0.46 10.4 4.1 1.8 1 0 0 1 1 1 0 PHD-finger HMG_box_2 PF09011.10 PXF49383.1 - 6.5 7.4 11.1 0.058 14.0 2.2 2.3 2 0 0 2 2 2 0 HMG-box domain MIF4G PF02854.19 PXF49384.1 - 1.2e-38 132.9 0.0 3.3e-14 53.0 0.0 4.3 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 PXF49384.1 - 3.8e-16 60.0 8.7 3.8e-16 60.0 8.7 4.1 3 1 0 3 3 3 1 Up-frameshift suppressor 2 DUF2458 PF10454.9 PXF49384.1 - 1.3 8.7 11.7 0.28 10.8 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Bystin PF05291.11 PXF49385.1 - 1.6e-115 385.4 0.3 2.3e-115 384.9 0.3 1.2 1 0 0 1 1 1 1 Bystin KH_8 PF17903.1 PXF49386.1 - 0.00092 19.3 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 PXF49386.1 - 0.00097 18.9 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 KH domain DUF819 PF05684.12 PXF49387.1 - 2e-68 231.2 16.7 2.4e-68 230.9 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) FAD_binding_3 PF01494.19 PXF49388.1 - 1.2e-10 41.2 0.1 2.9e-10 39.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PXF49388.1 - 0.05 12.3 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 PXF49388.1 - 0.084 11.9 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 PXF49388.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DEC-1_N PF04625.13 PXF49388.1 - 0.26 10.3 0.4 0.37 9.8 0.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAD_binding_3 PF01494.19 PXF49389.1 - 1.1e-07 31.5 0.1 1.4e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 PXF49389.1 - 0.0004 19.5 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase eIF-1a PF01176.19 PXF49390.1 - 2.7e-22 78.3 0.1 4.1e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L13 PF00572.18 PXF49391.1 - 1.7e-10 41.2 0.3 9.9e-09 35.5 0.3 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 cobW PF02492.19 PXF49392.1 - 3.2e-42 144.1 2.3 3.4e-42 144.0 1.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PXF49392.1 - 1.1e-07 31.7 0.2 2.6e-07 30.4 0.1 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 PXF49392.1 - 0.00011 21.8 0.7 0.038 13.5 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 PXF49392.1 - 0.00014 21.0 1.7 0.14 11.1 0.1 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 PXF49392.1 - 0.00019 21.9 0.1 0.00042 20.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF49392.1 - 0.00024 21.0 0.5 0.43 10.5 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 PXF49392.1 - 0.0011 19.2 0.2 0.0052 17.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PXF49392.1 - 0.0016 18.2 0.1 0.0098 15.7 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 PXF49392.1 - 0.0037 17.0 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 PXF49392.1 - 0.0053 16.9 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 PXF49392.1 - 0.0072 16.1 0.2 0.029 14.2 0.2 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Arf PF00025.21 PXF49392.1 - 0.014 14.9 5.2 0.49 9.8 0.4 3.0 2 1 1 3 3 3 0 ADP-ribosylation factor family ATPase_2 PF01637.18 PXF49392.1 - 0.056 13.3 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 PXF49392.1 - 0.06 13.4 0.3 0.33 11.1 0.0 2.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF815 PF05673.13 PXF49392.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PXF49392.1 - 0.074 12.3 0.1 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 PXF49392.1 - 0.08 13.5 0.2 0.38 11.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 PXF49392.1 - 0.15 12.6 0.7 0.55 10.7 0.7 2.1 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.25 PXF49394.1 - 4.5e-76 255.7 0.0 5.2e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49394.1 - 4.5e-32 111.4 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49394.1 - 0.00037 19.9 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF49394.1 - 0.0006 18.9 0.1 0.0012 17.8 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PXF49394.1 - 0.0037 16.4 0.1 0.0084 15.2 0.1 1.6 1 1 1 2 2 2 1 Seadornavirus VP7 APH PF01636.23 PXF49394.1 - 0.0057 16.6 1.0 0.039 13.9 0.1 2.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 PXF49394.1 - 0.011 15.0 0.1 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATase_2 PF00310.21 PXF49399.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Abhydrolase_1 PF00561.20 PXF49401.1 - 7.6e-20 71.6 0.0 4.2e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF49401.1 - 6.6e-16 59.6 0.0 7.4e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF49401.1 - 2.6e-10 40.0 0.1 6.6e-10 38.7 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PXF49401.1 - 1e-08 35.2 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 PXF49401.1 - 0.00011 22.0 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 PXF49401.1 - 0.00011 21.0 0.0 0.00024 19.9 0.0 1.6 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 PXF49401.1 - 0.00026 20.0 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PXF49401.1 - 0.00062 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.20 PXF49401.1 - 0.006 16.7 0.2 0.0062 16.7 0.2 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 PXF49401.1 - 0.0095 15.7 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 PXF49401.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2048 PF09752.9 PXF49401.1 - 0.026 13.6 0.1 0.038 13.1 0.1 1.5 1 1 0 1 1 1 0 Abhydrolase domain containing 18 LIDHydrolase PF10230.9 PXF49401.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 PXF49401.1 - 0.034 14.0 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Peptidase_M19 PF01244.21 PXF49401.1 - 0.053 12.7 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Abhydrolase_2 PF02230.16 PXF49401.1 - 0.057 13.2 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PXF49401.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 PXF49401.1 - 0.083 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 PXF49401.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 PXF49401.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PXF49401.1 - 0.13 11.8 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 PXF49401.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GHMP_kinases_N PF00288.26 PXF49402.1 - 3.4e-06 27.2 0.1 6.2e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PXF49402.1 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal CSS-motif PF12792.7 PXF49402.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 CSS motif domain associated with EAL APS_kinase PF01583.20 PXF49402.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC1 PF03109.16 PXF49403.1 - 1.1e-25 90.1 0.0 2.5e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 PXF49403.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PXF49403.1 - 0.0075 15.7 0.0 0.079 12.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PXF49403.1 - 0.02 14.8 0.1 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF5522 PF17653.1 PXF49404.1 - 2.9e-11 43.1 12.3 1e-09 38.2 12.3 2.7 1 1 0 1 1 1 1 Family of unknown function (DUF5522) CENP-F_leu_zip PF10473.9 PXF49405.1 - 0.2 11.7 6.2 0.041 13.9 1.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Octopine_DH PF02317.17 PXF49406.1 - 1.4e-32 112.9 0.0 1.9e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.17 PXF49406.1 - 0.16 12.6 0.0 0.39 11.3 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Palm_thioest PF02089.15 PXF49407.1 - 5e-06 26.5 0.0 7.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 PXF49407.1 - 8.6e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 PXF49407.1 - 0.00023 20.9 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PXF49407.1 - 0.00075 19.3 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 PXF49407.1 - 0.00083 20.0 1.9 0.00083 20.0 1.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF49407.1 - 0.0076 15.5 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 CCT PF06203.14 PXF49408.1 - 1.7e-16 59.9 12.4 2.9e-16 59.2 12.4 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 PXF49408.1 - 0.18 11.7 4.1 0.45 10.5 4.1 1.7 1 0 0 1 1 1 0 Divergent CCT motif Acyl-CoA_dh_M PF02770.19 PXF49409.1 - 9.9e-15 54.5 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 PXF49409.1 - 2.4e-09 37.0 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 PXF49409.1 - 4.6e-08 33.4 2.0 0.0013 18.9 0.1 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 PXF49409.1 - 0.0017 18.9 0.0 0.0034 17.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.16 PXF49409.1 - 0.009 16.7 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Bmt2 PF11968.8 PXF49410.1 - 3.4e-42 144.8 0.0 5e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_11 PF08241.12 PXF49410.1 - 0.00061 20.4 1.0 0.1 13.3 0.0 3.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49410.1 - 0.02 14.7 0.0 0.059 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Flavodoxin_2 PF02525.17 PXF49410.1 - 0.021 14.5 1.8 2.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Flavodoxin-like fold PX PF00787.24 PXF49411.1 - 2.5e-10 40.3 0.0 2.1e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 PX domain Ribosomal_L17 PF01196.19 PXF49411.1 - 0.024 15.5 0.7 0.069 14.1 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L17 NOG1_N PF17835.1 PXF49411.1 - 0.086 12.8 1.9 8.5 6.3 0.1 2.9 3 0 0 3 3 3 0 NOG1 N-terminal helical domain APG6_N PF17675.1 PXF49411.1 - 0.44 11.1 8.3 2.6 8.6 2.0 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF1978 PF09321.10 PXF49411.1 - 0.92 8.8 6.8 0.13 11.5 2.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) Rop PF01815.16 PXF49411.1 - 1.1 9.2 2.9 0.84 9.6 0.5 2.2 3 0 0 3 3 3 0 Rop protein Vps5 PF09325.10 PXF49411.1 - 1.1 8.7 7.1 0.33 10.5 3.1 2.0 2 0 0 2 2 2 0 Vps5 C terminal like P4Ha_N PF08336.11 PXF49411.1 - 1.4 9.0 4.2 0.99 9.4 0.2 2.7 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Apolipoprotein PF01442.18 PXF49411.1 - 3.3 7.5 14.7 1.1 9.2 6.6 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain GrpE PF01025.19 PXF49411.1 - 3.5 7.3 6.3 3.3 7.4 0.8 2.3 2 0 0 2 2 2 0 GrpE Sigma70_ner PF04546.13 PXF49411.1 - 4.6 7.1 7.4 0.92 9.4 1.6 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Ax_dynein_light PF10211.9 PXF49411.1 - 7.1 6.5 6.9 13 5.7 0.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain RRF PF01765.19 PXF49411.1 - 7.2 6.5 5.7 12 5.8 0.2 2.5 2 1 0 2 2 2 0 Ribosome recycling factor Pyr_redox_2 PF07992.14 PXF49412.1 - 1.3e-06 27.9 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF49412.1 - 0.092 13.3 0.0 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4042 PF13251.6 PXF49413.1 - 2.2e-14 53.5 1.4 8.3e-14 51.7 1.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) HEAT PF02985.22 PXF49413.1 - 8.8e-05 22.4 9.2 1.2 9.6 0.0 5.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 PXF49413.1 - 0.0026 18.1 3.2 7.6 7.0 0.1 5.3 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 PXF49413.1 - 0.0027 18.2 10.1 11 6.6 0.2 5.4 5 0 0 5 5 5 2 HEAT-like repeat T2SSF PF00482.23 PXF49413.1 - 0.056 13.4 0.4 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F BORCS8 PF10167.9 PXF49414.1 - 3.6e-06 26.9 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 DUF3110 PF11360.8 PXF49416.1 - 5.2e-09 36.2 0.0 2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3110) HMGL-like PF00682.19 PXF49417.1 - 7.3e-74 248.6 0.0 8.6e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Aminotran_3 PF00202.21 PXF49418.1 - 4.6e-54 183.6 0.0 6.1e-53 179.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 PXF49418.1 - 3e-15 56.6 0.0 4.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Nucleopor_Nup85 PF07575.13 PXF49419.1 - 1.7e-45 155.7 0.0 1.1e-44 153.0 0.0 1.9 1 1 0 1 1 1 1 Nup85 Nucleoporin Nup84_Nup100 PF04121.13 PXF49419.1 - 0.00098 17.3 0.1 0.0014 16.8 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PAP_fibrillin PF04755.12 PXF49420.1 - 2.5e-26 92.8 0.0 1.5e-25 90.3 0.0 1.9 1 1 0 1 1 1 1 PAP_fibrillin Pterin_bind PF00809.22 PXF49421.1 - 4.4e-74 249.2 0.0 5.3e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 PXF49421.1 - 7.3e-24 84.4 0.0 2.8e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HEAT_2 PF13646.6 PXF49422.1 - 1.9e-16 60.2 3.3 1.1e-12 48.1 0.1 2.9 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 PXF49422.1 - 1.6e-05 24.7 0.3 0.02 15.1 0.1 3.3 2 0 0 2 2 2 2 HEAT repeat Vitellogenin_N PF01347.22 PXF49422.1 - 0.0022 16.5 0.0 0.0031 16.0 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region DDE_5 PF13546.6 PXF49422.1 - 0.14 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease HEAT_EZ PF13513.6 PXF49422.1 - 2 9.0 14.7 0.13 12.8 0.9 4.4 4 1 1 5 5 5 0 HEAT-like repeat MGDG_synth PF06925.11 PXF49423.1 - 1.6e-28 99.9 0.0 3.3e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 PXF49423.1 - 5.2e-14 52.6 0.0 8.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 PXF49423.1 - 1.1e-05 25.8 0.1 4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 PXF49423.1 - 0.00014 20.9 0.0 0.00031 19.7 0.0 1.6 1 1 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_4 PF13439.6 PXF49423.1 - 0.051 13.6 3.0 0.47 10.4 3.0 2.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_6 PF08030.12 PXF49423.1 - 0.052 13.7 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Glyco_trans_4_4 PF13579.6 PXF49423.1 - 0.44 11.0 10.2 10 6.5 10.2 3.2 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain TIG PF01833.24 PXF49424.1 - 0.00012 22.0 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain LRR_4 PF12799.7 PXF49426.1 - 9.9e-05 22.6 17.1 0.026 14.9 0.1 6.2 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) Ribosomal_60s PF00428.19 PXF49427.1 - 1.9e-21 76.4 7.8 2.3e-21 76.2 7.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CCB2_CCB4 PF11152.8 PXF49428.1 - 2.9e-09 36.5 0.2 4.8e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 HMGL-like PF00682.19 PXF49429.1 - 6.9e-94 314.3 0.4 9.9e-94 313.8 0.4 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 PXF49429.1 - 6.4e-33 113.5 0.9 1.1e-32 112.7 0.9 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Spermine_synth PF01564.17 PXF49431.1 - 4.4e-45 153.4 0.0 5.9e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PXF49431.1 - 6.5e-13 48.4 0.3 1.2e-12 47.5 0.0 1.6 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Methyltransf_30 PF05430.11 PXF49431.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 PXF49431.1 - 7e-05 23.5 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L27e PF01777.18 PXF49432.1 - 5.9e-27 93.9 0.3 1.1e-26 93.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 PXF49432.1 - 0.0015 18.4 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 KOW motif Ribosomal_S5_C PF03719.15 PXF49433.1 - 1.3e-21 75.8 0.0 2.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 PXF49433.1 - 1.8e-21 75.9 0.2 9.9e-21 73.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain XPG_N PF00752.17 PXF49434.1 - 1.7e-21 76.6 0.0 4.1e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 PXF49434.1 - 2.1e-21 76.0 0.1 4.3e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 PXF49434.1 - 0.00015 21.3 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Pox_G5 PF04599.12 PXF49434.1 - 0.039 13.0 0.4 0.079 11.9 0.3 1.4 1 1 0 1 1 1 0 Poxvirus G5 protein 5_3_exonuc PF01367.20 PXF49434.1 - 0.16 12.6 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HemY_N PF07219.13 PXF49434.1 - 0.16 12.1 2.1 0.37 11.0 2.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus EMP24_GP25L PF01105.24 PXF49435.1 - 4.4e-44 150.6 0.3 5.1e-44 150.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BspA_v PF18220.1 PXF49435.1 - 0.028 14.5 0.0 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 Adhesin BspA variable domain PDCD2_C PF04194.13 PXF49436.1 - 1.9e-25 89.9 0.2 1.9e-25 89.9 0.2 2.9 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain Oxysterol_BP PF01237.18 PXF49437.1 - 2.7e-90 302.9 0.0 4.2e-90 302.3 0.0 1.3 1 1 0 1 1 1 1 Oxysterol-binding protein DCP1 PF06058.13 PXF49438.1 - 4e-27 94.5 0.6 6.8e-27 93.7 0.6 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family F-box-like PF12937.7 PXF49439.1 - 0.0041 17.0 0.3 0.019 14.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like LysM PF01476.20 PXF49439.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 LysM domain CUE PF02845.16 PXF49439.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 CUE domain F-box PF00646.33 PXF49439.1 - 0.051 13.5 0.4 0.21 11.5 0.1 2.2 3 0 0 3 3 3 0 F-box domain TPR_1 PF00515.28 PXF49440.1 - 5e-15 54.6 5.0 2.1e-08 33.6 0.5 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49440.1 - 4.4e-10 38.9 12.4 2.2e-05 24.2 0.6 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49440.1 - 1.5e-09 37.4 1.4 3.2e-05 23.5 2.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 PXF49440.1 - 2.9e-07 30.7 12.5 5.6e-05 23.3 2.1 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF49440.1 - 2.1e-05 24.2 6.2 0.13 12.2 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49440.1 - 2.3e-05 24.3 7.8 0.018 15.2 0.2 4.6 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49440.1 - 0.0004 20.2 3.0 8 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49440.1 - 0.00041 20.5 1.3 0.09 13.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49440.1 - 0.0013 18.8 5.4 0.69 10.1 0.4 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49440.1 - 0.0028 18.4 8.9 0.49 11.4 0.8 4.5 2 1 2 4 4 3 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 PXF49440.1 - 0.0049 16.6 0.0 0.032 14.0 0.0 2.3 3 0 0 3 3 3 1 Homodimerisation domain of SGTA TPR_16 PF13432.6 PXF49440.1 - 0.043 14.5 0.4 0.043 14.5 0.4 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49440.1 - 0.12 12.9 11.2 0.081 13.4 1.4 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat SGT1 PF07093.11 PXF49440.1 - 0.12 10.7 5.9 0.085 11.3 0.8 2.1 2 0 0 2 2 2 0 SGT1 protein DUF2999 PF11212.8 PXF49440.1 - 0.18 12.1 0.5 1.1 9.6 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) XPC-binding PF09280.11 PXF49440.1 - 0.19 11.5 1.6 0.35 10.6 1.6 1.5 1 0 0 1 1 1 0 XPC-binding domain Cas_Csy4 PF09618.10 PXF49440.1 - 0.38 10.9 2.6 1.2 9.3 1.4 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) DUF1943 PF09172.11 PXF49440.1 - 1.4 8.0 5.8 4.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Virulence_fact PF13769.6 PXF49440.1 - 1.7 8.9 7.1 0.85 9.9 0.6 3.0 2 1 1 3 3 3 0 Virulence factor TPR_6 PF13174.6 PXF49440.1 - 2.5 8.9 6.8 11 6.9 0.1 4.3 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF4079 PF13301.6 PXF49442.1 - 5.5e-15 55.8 5.5 1e-14 54.9 5.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF4405 PF14358.6 PXF49442.1 - 0.0031 18.0 6.9 0.011 16.3 0.3 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF4405) DUF4149 PF13664.6 PXF49442.1 - 0.018 15.4 1.1 0.32 11.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) MrpF_PhaF PF04066.13 PXF49442.1 - 0.41 11.1 0.1 0.41 11.1 0.1 3.1 3 0 0 3 3 3 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) HEAT PF02985.22 PXF49443.1 - 3.7e-07 29.8 8.7 2.1 8.8 0.4 6.3 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 PXF49443.1 - 1.2e-06 28.8 6.8 0.00036 20.9 1.7 5.0 4 1 2 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 PXF49443.1 - 4.6e-05 22.2 9.3 0.0019 16.9 2.8 4.8 4 2 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.7 PXF49443.1 - 0.00014 22.0 2.4 0.21 11.6 0.2 3.7 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PXF49443.1 - 0.0034 17.9 12.9 5.6 7.6 0.0 5.6 5 0 0 5 5 5 3 HEAT-like repeat Cohesin_HEAT PF12765.7 PXF49443.1 - 3.1 8.2 11.7 0.033 14.5 0.8 3.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion PRP1_N PF06424.12 PXF49444.1 - 1.3e-29 103.6 7.8 2.6e-29 102.5 7.8 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 PXF49444.1 - 1.8e-13 50.1 47.8 0.00068 20.2 0.1 12.8 8 4 6 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49444.1 - 7.5e-10 39.2 3.9 0.097 13.2 0.3 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49444.1 - 0.0078 16.3 0.7 42 4.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MHB PF16525.5 PXF49444.1 - 0.1 12.9 0.6 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Haemophore, haem-binding TPR_10 PF13374.6 PXF49444.1 - 0.13 12.2 6.7 3.3 7.7 0.1 5.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 PXF49444.1 - 6.3 6.7 6.9 0.87 9.5 0.1 2.9 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) Rad17 PF03215.15 PXF49445.1 - 4.7e-16 59.2 0.0 8.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 PXF49445.1 - 0.00029 21.3 0.0 0.00072 20.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 PXF49445.1 - 0.00092 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 PXF49445.1 - 0.015 15.6 0.0 0.048 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PXF49445.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PXF49445.1 - 0.13 11.6 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin OTU PF02338.19 PXF49446.1 - 4.7e-19 69.1 0.7 1.1e-18 68.0 0.7 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PXF49446.1 - 3.6e-11 43.0 6.4 9e-08 31.9 0.9 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain Nucleo_P87 PF07267.11 PXF49446.1 - 1.3 7.8 13.3 0.026 13.4 4.6 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 BRCT PF00533.26 PXF49447.1 - 2.8e-08 34.0 0.2 9.6e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-HC5HC2H PF13771.6 PXF49447.1 - 5.7e-07 29.7 31.4 2.5e-05 24.5 8.3 4.9 4 1 0 4 4 4 2 PHD-like zinc-binding domain zf-RING_2 PF13639.6 PXF49447.1 - 6.1e-07 29.7 11.4 6.1e-07 29.7 11.4 4.7 5 0 0 5 5 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PXF49447.1 - 1.7e-06 27.8 9.9 1.7e-06 27.8 9.9 3.6 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PXF49447.1 - 2.1e-06 27.5 7.3 2.1e-06 27.5 7.3 5.5 4 1 1 5 5 5 1 PHD-finger zf-C3HC4_4 PF15227.6 PXF49447.1 - 3.1e-06 27.2 12.1 3.1e-06 27.2 12.1 3.3 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PXF49447.1 - 3.6e-06 26.7 12.6 3.6e-06 26.7 12.6 3.9 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF49447.1 - 5.8e-06 26.1 12.8 5.8e-06 26.1 12.8 3.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PXF49447.1 - 2.4e-05 24.2 10.5 2.4e-05 24.2 10.5 3.5 3 1 1 4 4 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 PXF49447.1 - 6.5e-05 22.7 3.4 6.5e-05 22.7 3.4 2.3 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 PXF49447.1 - 0.00018 21.4 8.4 0.00029 20.8 5.4 2.8 1 1 1 2 2 2 1 RING-type zinc-finger PHD_2 PF13831.6 PXF49447.1 - 0.00019 20.9 3.8 0.00019 20.9 3.8 4.5 4 0 0 4 4 4 1 PHD-finger Prok-RING_4 PF14447.6 PXF49447.1 - 0.00037 20.3 9.2 0.00037 20.3 9.2 3.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-HC5HC2H_2 PF13832.6 PXF49447.1 - 0.0077 16.4 7.1 0.0077 16.4 7.1 4.6 3 1 1 5 5 5 2 PHD-zinc-finger like domain BRCT_2 PF16589.5 PXF49447.1 - 0.037 14.4 0.1 5 7.6 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PXF49447.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_4 PF14570.6 PXF49447.1 - 0.17 11.7 7.8 1.2 9.0 7.8 2.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RVT PF13966.6 PXF49447.1 - 3.3 8.5 0.0 3.3 8.5 0.0 4.2 5 1 1 6 6 4 0 zinc-binding in reverse transcriptase KH_8 PF17903.1 PXF49448.1 - 2.2e-31 107.8 0.4 8.5e-31 105.9 0.0 2.1 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 PXF49448.1 - 0.003 17.3 0.0 0.014 15.2 0.0 2.1 1 1 1 2 2 2 1 KH domain Integrase_Zn PF02022.19 PXF49448.1 - 0.05 13.6 0.1 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF1757 PF08560.10 PXF49449.1 - 0.0045 17.0 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Noelin-1 PF12308.8 PXF49449.1 - 0.035 14.1 0.1 0.075 13.0 0.1 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein CYTL1 PF15153.6 PXF49449.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 ETRAMP PF09716.10 PXF49449.1 - 0.75 9.9 3.0 1.3 9.1 0.1 2.7 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) LapA_dom PF06305.11 PXF49449.1 - 6.8 6.6 6.2 1.2 9.0 0.1 2.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Y_phosphatase2 PF03162.13 PXF49450.1 - 5e-42 143.3 0.0 6.7e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PNTB PF02233.16 PXF49451.1 - 8.2e-162 539.3 24.6 8.2e-162 539.3 24.6 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 PXF49451.1 - 7.7e-71 237.8 2.5 2.2e-70 236.3 2.5 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PXF49451.1 - 7.1e-37 126.7 1.7 1.3e-35 122.6 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 PXF49451.1 - 1.2e-28 99.4 2.0 1.2e-28 99.4 2.0 4.4 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 PXF49451.1 - 0.005 16.2 0.9 0.4 10.0 0.2 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 PXF49454.1 - 7.1e-13 49.4 0.1 1.4e-12 48.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_33 PF13671.6 PXF49454.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.19 PXF49455.1 - 2.7e-15 56.5 0.0 4.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1712 PF08217.11 PXF49456.1 - 0.0069 14.9 4.1 0.011 14.3 3.8 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Mod_r PF07200.13 PXF49456.1 - 0.026 14.6 5.5 0.04 14.0 5.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BCDHK_Adom3 PF10436.9 PXF49457.1 - 0.046 13.5 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Transposase_21 PF02992.14 PXF49458.1 - 1.8e-05 24.1 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 PXF49458.1 - 0.0048 16.2 0.0 0.15 11.2 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase F-protein PF00469.20 PXF49461.1 - 0.42 10.2 7.0 0.68 9.5 1.3 2.0 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef AMP-binding PF00501.28 PXF49464.1 - 0.00052 18.7 0.1 0.00093 17.9 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Lipase_GDSL_2 PF13472.6 PXF49465.1 - 2.7e-05 24.7 0.0 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Kinesin PF00225.23 PXF49466.1 - 2.1e-91 306.3 0.1 6e-91 304.8 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF49466.1 - 3e-15 56.5 0.0 9.1e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 PXF49466.1 - 4.5e-07 30.2 0.0 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PXF49466.1 - 0.002 18.2 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3175 PF11373.8 PXF49466.1 - 0.031 14.5 0.0 0.17 12.1 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) DUF3110 PF11360.8 PXF49467.1 - 3e-26 91.5 0.0 4.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) Adeno_terminal PF02459.15 PXF49467.1 - 1.3 7.3 6.8 1.9 6.7 6.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein ODR4-like PF14778.6 PXF49468.1 - 3.1e-30 105.4 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Methyltransf_10 PF05971.12 PXF49469.1 - 4.3e-51 174.0 0.1 3e-36 125.3 0.0 2.1 1 1 1 2 2 2 2 RNA methyltransferase MTS PF05175.14 PXF49469.1 - 3e-08 33.4 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PXF49469.1 - 3.5e-07 29.9 0.0 5.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PXF49469.1 - 1.1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49469.1 - 0.00027 21.6 0.0 0.00084 20.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 PXF49469.1 - 0.006 16.3 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 PXF49469.1 - 0.0066 17.2 0.0 0.016 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PXF49469.1 - 0.0091 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase SNAD4 PF18750.1 PXF49469.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 tRNA_U5-meth_tr PF05958.11 PXF49469.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ribosomal_S10 PF00338.22 PXF49470.1 - 1.2e-17 63.9 0.1 1.8e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e EXOSC1 PF10447.9 PXF49471.1 - 8e-13 49.0 1.6 3.1e-08 34.2 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 PXF49471.1 - 4.2e-06 26.5 0.1 8.6e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RNA_pol_Rpb4 PF03874.16 PXF49472.1 - 5.1e-14 52.7 0.0 8.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Imm5 PF14423.6 PXF49472.1 - 0.015 15.5 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 SAM_3 PF18016.1 PXF49472.1 - 0.069 13.0 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NUDIX PF00293.28 PXF49473.1 - 1.4e-13 51.0 0.5 2.2e-13 50.4 0.5 1.3 1 1 0 1 1 1 1 NUDIX domain Pyrid_oxidase_2 PF13883.6 PXF49474.1 - 2.3e-20 73.2 0.0 4.8e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PXF49474.1 - 6.8e-10 39.0 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 PXF49474.1 - 4.5e-07 30.4 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) AAA PF00004.29 PXF49475.1 - 3.2e-37 127.9 0.0 7.2e-34 117.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF49475.1 - 5.8e-09 35.6 0.2 1.1e-08 34.7 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PXF49475.1 - 1.5e-06 28.7 1.3 6.5e-05 23.4 0.2 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PXF49475.1 - 0.00014 22.2 0.1 0.0074 16.6 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PXF49475.1 - 0.00021 21.3 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PXF49475.1 - 0.0003 21.0 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PXF49475.1 - 0.0011 18.6 0.1 0.0048 16.4 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 PXF49475.1 - 0.0016 18.2 0.0 0.042 13.6 0.0 2.3 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 PXF49475.1 - 0.004 17.3 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 PXF49475.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PXF49475.1 - 0.016 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AFG1_ATPase PF03969.16 PXF49475.1 - 0.019 13.9 0.0 0.068 12.0 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase AAA_18 PF13238.6 PXF49475.1 - 0.021 15.4 0.0 0.059 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PXF49475.1 - 0.022 15.2 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 PXF49475.1 - 0.028 14.3 0.1 0.4 10.6 0.0 2.6 2 1 1 3 3 3 0 NACHT domain TsaE PF02367.17 PXF49475.1 - 0.042 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 PXF49475.1 - 0.045 13.4 0.0 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 Guanylate kinase DUF3429 PF11911.8 PXF49476.1 - 8.5e-30 103.9 7.9 1.2e-29 103.5 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Gcd10p PF04189.13 PXF49478.1 - 0.0011 18.1 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Peptidase_S64 PF08192.11 PXF49478.1 - 0.0035 15.9 0.0 0.0042 15.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 Saw1 PF11561.8 PXF49478.1 - 0.0076 15.8 0.2 0.0094 15.5 0.2 1.2 1 0 0 1 1 1 1 Single strand annealing-weakened 1 NAGLU_C PF12972.7 PXF49478.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Gln-synt_C PF00120.24 PXF49479.1 - 1.3e-73 248.0 0.0 1.7e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1658 PF07871.11 PXF49479.1 - 0.2 11.6 0.5 0.67 10.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) H_PPase PF03030.16 PXF49480.1 - 1.8e-36 126.1 40.2 2.2e-36 125.8 36.6 2.6 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase TIP120 PF08623.10 PXF49481.1 - 5.1e-40 137.0 7.0 2.8e-38 131.3 0.2 4.8 5 1 0 5 5 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 PXF49481.1 - 9.5e-16 56.6 35.9 0.0017 18.5 0.1 12.8 14 0 0 14 14 12 4 HEAT repeat HEAT_2 PF13646.6 PXF49481.1 - 2.5e-13 50.2 28.9 0.0019 18.5 0.3 9.4 8 4 3 11 11 11 4 HEAT repeats HEAT_EZ PF13513.6 PXF49481.1 - 2.1e-08 34.5 21.5 0.58 10.7 0.1 10.9 10 1 2 12 12 11 2 HEAT-like repeat Adaptin_N PF01602.20 PXF49481.1 - 5.5e-07 28.5 29.8 0.011 14.3 1.9 4.9 2 2 0 4 4 4 4 Adaptin N terminal region Cnd1 PF12717.7 PXF49481.1 - 3.7e-05 23.8 19.3 0.015 15.3 0.1 8.5 7 2 4 11 11 11 1 non-SMC mitotic condensation complex subunit 1 HEAT_UF PF18817.1 PXF49481.1 - 0.029 14.6 5.4 0.14 12.5 0.0 3.7 3 0 0 3 3 3 0 Repeat of uncharacterized protein PH0542 DUF2019 PF09450.10 PXF49481.1 - 0.059 13.3 0.5 1.2 9.1 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) CLASP_N PF12348.8 PXF49481.1 - 0.084 12.4 12.5 4.8 6.7 0.0 6.5 7 1 1 8 8 8 0 CLASP N terminal PknH_C PF14032.6 PXF49481.1 - 0.18 11.6 2.3 0.6 9.9 0.2 2.6 2 0 0 2 2 2 0 PknH-like extracellular domain Arm PF00514.23 PXF49481.1 - 0.19 11.8 14.4 2.2 8.4 0.1 5.9 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat ParcG PF10274.9 PXF49481.1 - 0.19 11.8 2.4 4 7.5 0.1 3.9 4 1 1 5 5 5 0 Parkin co-regulated protein RRN3 PF05327.11 PXF49481.1 - 0.75 8.3 6.1 8.3 4.8 0.3 2.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 HEAT_PBS PF03130.16 PXF49481.1 - 0.91 10.4 5.4 8.2 7.4 0.1 5.4 5 0 0 5 5 3 0 PBS lyase HEAT-like repeat Cupin_4 PF08007.12 PXF49481.1 - 2 7.8 7.0 33 3.8 0.1 4.1 4 1 1 5 5 5 0 Cupin superfamily protein Sec7_N PF12783.7 PXF49481.1 - 2.6 7.9 7.6 1.9 8.4 0.9 3.7 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 PXF49481.1 - 7.8 6.4 8.1 3.5 7.6 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) CLTH PF10607.9 PXF49482.1 - 3e-30 105.1 1.1 5.1e-30 104.3 1.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PXF49482.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 LisH Bcr-Abl_Oligo PF09036.10 PXF49482.1 - 2.7 8.0 6.7 13 5.8 0.5 3.4 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain FUSC PF04632.12 PXF49482.1 - 9.6 4.6 9.2 0.44 9.0 2.6 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family mRNA_cap_enzyme PF01331.19 PXF49483.1 - 3.9e-30 105.2 0.0 3.1e-29 102.2 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 PXF49483.1 - 3e-15 56.8 0.0 6.9e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 PXF49483.1 - 0.011 15.4 0.0 0.2 11.2 0.0 2.4 2 1 1 3 3 3 0 ATP dependent DNA ligase domain tRNA-synt_2 PF00152.20 PXF49484.1 - 1.8e-95 319.7 0.0 2.7e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PXF49484.1 - 3.4e-11 42.9 0.0 5.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF49484.1 - 0.0088 15.6 0.1 1.8 8.0 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) VCBS PF13517.6 PXF49485.1 - 3.3e-20 72.4 12.9 3.5e-06 27.5 0.0 6.8 4 1 3 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF49485.1 - 1e-06 28.8 15.1 0.28 11.4 0.0 5.7 5 1 0 5 5 5 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 PXF49485.1 - 0.012 14.9 0.2 13 5.1 0.0 3.6 4 0 0 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region XPC-binding PF09280.11 PXF49486.1 - 2.5e-20 72.0 10.3 4.6e-20 71.1 10.3 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 PXF49486.1 - 1e-18 66.8 3.0 1.9e-14 53.2 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 PXF49486.1 - 7.8e-13 48.0 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PXF49486.1 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 PXF49486.1 - 0.00026 21.1 0.0 0.00048 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 PXF49486.1 - 0.0087 16.3 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 TUG ubiquitin-like domain DUF2407 PF10302.9 PXF49486.1 - 0.012 16.2 0.0 0.075 13.6 0.0 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Histone PF00125.24 PXF49488.1 - 1.8e-40 138.4 0.9 2.2e-40 138.0 0.6 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PXF49488.1 - 0.00051 20.3 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 PXF49488.1 - 0.0024 17.9 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFA2_Winged_2 PF18121.1 PXF49489.1 - 3.9e-07 29.6 0.1 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 HA2 PF04408.23 PXF49490.1 - 3.1e-21 75.7 0.4 1.1e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PXF49490.1 - 1.2e-12 48.1 0.0 2.9e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PXF49490.1 - 1.8e-09 37.8 0.0 4.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 PXF49490.1 - 6.3e-06 26.1 0.1 1.7e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PXF49490.1 - 9.2e-05 22.7 0.1 0.00038 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PXF49490.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PXF49490.1 - 0.0031 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 PXF49490.1 - 0.0047 16.7 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.6 PXF49490.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PXF49490.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 PXF49490.1 - 0.035 14.1 0.1 11 6.0 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 PXF49490.1 - 0.038 13.5 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PXF49490.1 - 0.047 14.1 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 PXF49490.1 - 0.052 14.1 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 PXF49490.1 - 0.055 13.6 1.0 0.23 11.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PXF49490.1 - 0.072 13.6 0.2 0.24 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 PXF49490.1 - 0.11 12.6 0.1 0.61 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 PXF49490.1 - 0.14 11.8 0.2 0.42 10.2 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Flavi_DEAD PF07652.14 PXF49490.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF3882 PF07066.11 PXF49490.1 - 0.21 11.7 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Lactococcus phage M3 protein dsDNA_bind PF01984.20 PXF49490.1 - 1.5 9.1 6.2 0.95 9.8 2.5 2.6 2 1 1 3 3 3 0 Double-stranded DNA-binding domain ArfGap PF01412.18 PXF49491.1 - 6.9e-21 74.5 0.0 6.9e-21 74.5 0.0 2.6 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf SOBP PF15279.6 PXF49491.1 - 3.1 8.3 4.9 5.6 7.5 4.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 PXF49491.1 - 3.6 4.6 5.5 4.2 4.3 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CENP-I PF07778.11 PXF49491.1 - 4.5 5.9 6.7 6.7 5.3 6.7 1.2 1 0 0 1 1 1 0 Mis6 DUF3292 PF11696.8 PXF49491.1 - 5.1 5.3 8.5 7.2 4.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Neur_chan_memb PF02932.16 PXF49491.1 - 6.5 6.7 7.5 9.6 6.2 7.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bPH_2 PF03703.14 PXF49492.1 - 2e-16 59.9 0.1 2.7e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain PsbK PF02533.15 PXF49492.1 - 0.033 14.3 0.3 0.044 13.9 0.3 1.2 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component bPH_3 PF14470.6 PXF49492.1 - 0.036 14.4 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain WD40 PF00400.32 PXF49493.1 - 2.5e-41 138.9 34.1 3.4e-07 30.9 1.3 11.9 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF49493.1 - 8.8e-14 51.6 6.0 0.00016 21.9 0.2 8.0 2 1 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain NB-ARC PF00931.22 PXF49493.1 - 4.9e-11 42.3 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Nucleoporin_N PF08801.11 PXF49493.1 - 2.2e-05 23.4 1.7 4.3 6.0 0.0 4.3 2 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 PXF49493.1 - 3.1e-05 22.8 10.8 0.28 9.8 0.0 6.5 5 1 3 8 8 8 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 PXF49493.1 - 0.0017 18.8 0.5 0.0078 16.6 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 PXF49493.1 - 0.0024 16.5 2.2 0.56 8.7 0.0 3.2 2 1 0 3 3 3 2 Cytochrome D1 heme domain AAA_30 PF13604.6 PXF49493.1 - 0.0034 17.1 0.1 0.0089 15.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain Ge1_WD40 PF16529.5 PXF49493.1 - 0.0038 16.2 2.9 3.9 6.3 0.0 4.3 2 2 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 PXF49493.1 - 0.0054 17.0 0.0 0.048 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain APAF1_C PF17908.1 PXF49493.1 - 0.09 12.8 0.0 0.29 11.1 0.0 1.9 1 1 0 1 1 1 0 APAF-1 helical domain Myc_target_1 PF15179.6 PXF49493.1 - 2.4 8.0 6.8 5 7.0 6.8 1.5 1 0 0 1 1 1 0 Myc target protein 1 Glyco_hydro_130 PF04041.13 PXF49494.1 - 0.00045 19.3 0.0 0.0023 16.9 0.0 2.1 2 1 0 2 2 2 1 beta-1,4-mannooligosaccharide phosphorylase EzrA PF06160.12 PXF49495.1 - 0.018 13.3 1.8 0.024 12.8 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NAM-associated PF14303.6 PXF49495.1 - 4.1 8.1 13.3 0.67 10.7 6.4 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain AMP-binding PF00501.28 PXF49496.1 - 1.3e-07 30.6 0.1 2.7e-07 29.6 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_1 PF00175.21 PXF49500.1 - 0.012 16.2 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4299 PF14132.6 PXF49501.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) PAP2 PF01569.21 PXF49503.1 - 9.6e-10 38.4 0.0 5.5e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 PAP2 superfamily VCPO_N PF17897.1 PXF49503.1 - 1.3e-06 28.4 0.1 3.9e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain Nodulin_late PF07127.11 PXF49503.1 - 0.041 14.2 1.3 0.15 12.4 0.1 2.2 2 0 0 2 2 2 0 Late nodulin protein DX PF01666.17 PXF49503.1 - 0.1 13.1 1.5 17 6.0 0.3 2.3 2 0 0 2 2 2 0 DX module EB PF01683.18 PXF49503.1 - 0.13 12.6 5.5 0.71 10.2 0.5 2.3 2 0 0 2 2 2 0 EB module Patatin PF01734.22 PXF49504.1 - 1.8e-09 38.0 0.0 7.6e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Gpr1_Fun34_YaaH PF01184.19 PXF49505.1 - 6.1e-16 58.6 14.3 7.9e-16 58.3 14.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Kinesin PF00225.23 PXF49509.1 - 4.9e-107 357.7 0.4 4.9e-107 357.7 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF49509.1 - 7.7e-26 90.8 0.1 3e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Fez1 PF06818.15 PXF49509.1 - 0.0072 16.8 24.1 0.14 12.6 9.9 2.4 2 0 0 2 2 2 2 Fez1 FlxA PF14282.6 PXF49509.1 - 0.032 14.2 0.5 0.032 14.2 0.5 3.4 3 0 0 3 3 3 0 FlxA-like protein HU-CCDC81_bac_2 PF18175.1 PXF49509.1 - 0.059 13.2 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 PCRF PF03462.18 PXF49509.1 - 0.27 11.1 11.9 0.015 15.1 4.2 2.5 2 1 0 2 2 2 0 PCRF domain PRKG1_interact PF15898.5 PXF49509.1 - 0.84 10.6 18.6 1.5 9.8 5.3 3.5 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF16 PF01519.16 PXF49509.1 - 1.7 9.2 7.6 0.28 11.7 0.7 3.0 4 0 0 4 4 4 0 Protein of unknown function DUF16 BRE1 PF08647.11 PXF49509.1 - 2.3 8.4 16.0 0.07 13.2 3.2 3.5 4 0 0 4 4 4 0 BRE1 E3 ubiquitin ligase PRCC PF10253.9 PXF49511.1 - 7.7 7.2 9.7 0.89 10.3 4.4 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting bZIP_1 PF00170.21 PXF49513.1 - 0.061 13.4 9.9 0.11 12.6 9.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 PXF49513.1 - 0.082 13.4 8.9 0.15 12.6 8.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor tRNA-synt_1e PF01406.19 PXF49514.1 - 4.3e-111 371.1 0.1 5.8e-111 370.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PXF49514.1 - 5.1e-13 48.5 1.0 2e-08 33.4 0.2 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 PXF49514.1 - 3.6e-10 40.1 0.4 1e-09 38.7 0.4 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 PXF49514.1 - 4.8e-05 21.8 0.0 0.00021 19.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 PXF49514.1 - 8.1e-05 21.7 0.0 0.048 12.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 PXF49514.1 - 0.04 12.8 0.1 1.7 7.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Pox_J1 PF03338.15 PXF49514.1 - 0.097 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Poxvirus J1 protein UVR PF02151.19 PXF49514.1 - 0.77 9.6 6.4 0.1 12.4 1.6 2.1 2 0 0 2 2 2 0 UvrB/uvrC motif WD40 PF00400.32 PXF49515.1 - 2e-18 66.4 9.9 0.00012 22.8 0.0 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.14 PXF49515.1 - 3.9e-18 65.5 11.2 6.5e-18 64.8 11.2 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 PXF49515.1 - 2.4e-06 27.7 0.0 3.4 8.0 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PXF49515.1 - 0.00066 19.6 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PXF49515.1 - 0.046 12.7 0.2 2.4 7.1 0.0 3.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 PXF49515.1 - 0.068 13.2 0.0 8 6.6 0.0 2.5 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region UPF0561 PF10573.9 PXF49515.1 - 0.84 9.8 6.2 2.1 8.5 6.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Agenet PF05641.12 PXF49516.1 - 1.1e-10 41.8 1.9 0.0052 17.2 0.2 3.4 3 0 0 3 3 3 3 Agenet domain Homeodomain PF00046.29 PXF49516.1 - 7.3e-10 38.5 0.1 1.7e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain MBD PF01429.19 PXF49516.1 - 0.00083 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain DUF4805 PF16063.5 PXF49516.1 - 0.0024 17.3 10.6 0.0024 17.3 10.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4805) DUF3801 PF12687.7 PXF49516.1 - 0.47 10.5 12.0 0.96 9.5 11.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) PRONE PF03759.13 PXF49517.1 - 1.6e-47 162.1 0.1 6.9e-47 160.0 0.1 1.8 1 1 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) MIT PF04212.18 PXF49517.1 - 0.0011 18.9 0.3 0.005 16.9 0.3 2.2 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain UPF0184 PF03670.13 PXF49517.1 - 0.058 13.8 1.6 0.26 11.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Fer4_16 PF13484.6 PXF49518.1 - 5.6e-21 75.2 5.6 1.1e-20 74.3 5.6 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain DUF1730 PF08331.10 PXF49518.1 - 1.3e-18 66.7 0.0 2.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_10 PF13237.6 PXF49518.1 - 1.7e-06 28.0 4.1 0.0047 17.0 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 PXF49518.1 - 1e-05 26.0 9.1 0.00049 20.6 10.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 PXF49518.1 - 0.0024 18.0 9.6 0.014 15.5 9.6 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 PXF49518.1 - 0.0028 17.8 10.0 0.051 13.8 10.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 PXF49518.1 - 0.011 15.6 17.7 0.092 12.6 6.8 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 PXF49518.1 - 0.024 14.7 14.6 0.047 13.8 5.2 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 PXF49518.1 - 0.032 14.4 2.3 0.82 9.9 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 PXF49518.1 - 0.16 12.9 14.3 2.7 9.1 6.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 PXF49518.1 - 0.25 11.8 8.9 5 7.6 10.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 PXF49518.1 - 1.2 9.4 14.9 1.2 9.4 0.7 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_17 PF13534.6 PXF49518.1 - 2 9.0 8.9 18 6.0 2.8 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain LSM PF01423.22 PXF49519.1 - 1.6e-18 66.1 0.1 2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SHOCT PF09851.9 PXF49520.1 - 0.0015 18.2 0.7 0.0015 18.2 0.7 3.0 3 1 1 4 4 4 1 Short C-terminal domain CLP1_P PF16575.5 PXF49521.1 - 1.3e-27 96.8 0.0 2.1e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 PXF49521.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PXF49521.1 - 0.0045 17.4 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Pox_A32 PF04665.12 PXF49521.1 - 0.0046 16.4 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein ABC_tran PF00005.27 PXF49521.1 - 0.045 14.3 0.1 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 PXF49521.1 - 0.057 13.7 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 PXF49521.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 PXF49521.1 - 0.069 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 PXF49521.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain CbiA PF01656.23 PXF49521.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 PXF49521.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 PXF49521.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 PXF49521.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PXF49521.1 - 0.16 11.8 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 PXF49521.1 - 0.24 10.6 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Med13_C PF06333.12 PXF49522.1 - 3.4e-10 39.7 1.1 3.4e-10 39.7 1.1 3.2 2 2 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 PXF49522.1 - 2.4e-05 24.3 0.8 2.4e-05 24.3 0.8 4.0 2 2 0 2 2 2 1 MID domain of medPIWI Trypsin PF00089.26 PXF49523.1 - 8.2e-34 117.3 0.4 1.1e-33 116.9 0.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PXF49523.1 - 6.6e-07 30.3 0.1 1.7e-06 29.0 0.1 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain FAA_hydrolase PF01557.18 PXF49524.1 - 1.8e-54 184.7 0.0 2.2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF1804 PF08822.11 PXF49524.1 - 0.18 11.8 0.2 0.28 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Cytochrom_C PF00034.21 PXF49525.1 - 4.9e-11 43.6 0.0 6.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 PXF49525.1 - 1e-05 25.7 0.8 1.9e-05 24.9 0.8 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PXF49525.1 - 0.0011 18.7 2.4 0.0061 16.3 2.4 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 PXF49525.1 - 0.038 14.4 0.1 4.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Cytochrome P460 HAD_2 PF13419.6 PXF49526.1 - 3.4e-27 95.7 0.0 4.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF49526.1 - 1.3e-11 45.2 0.0 2.6e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF49526.1 - 9.1e-05 22.9 0.0 0.00014 22.4 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 PXF49526.1 - 0.0032 17.1 0.0 0.25 10.9 0.0 2.1 1 1 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 PXF49526.1 - 0.0054 16.8 0.0 0.062 13.4 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF49526.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_3 PF08282.12 PXF49526.1 - 0.076 12.7 0.1 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 PXF49527.1 - 5.5e-14 52.2 12.4 8e-14 51.7 12.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PXF49527.1 - 1.6e-09 37.3 3.2 3e-09 36.4 3.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PXF49527.1 - 5.8e-08 32.4 13.0 9.2e-08 31.8 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF49527.1 - 6.4e-08 32.5 9.9 1.1e-07 31.7 9.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PXF49527.1 - 1.1e-07 31.6 11.4 1.7e-07 31.0 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF49527.1 - 1.2e-06 28.7 15.2 8.7e-06 25.9 15.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF49527.1 - 4.7e-06 26.5 10.2 7.1e-06 25.9 10.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PXF49527.1 - 5.3e-06 26.2 8.1 8.1e-06 25.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PXF49527.1 - 1.9e-05 24.4 13.0 0.00034 20.4 13.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF49527.1 - 5.8e-05 23.1 7.7 0.00014 21.8 7.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 PXF49527.1 - 0.011 15.6 5.3 0.018 14.8 5.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 PXF49527.1 - 0.054 13.7 10.6 0.11 12.6 10.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PXF49527.1 - 0.099 12.5 2.0 0.18 11.7 2.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TerY_C PF15616.6 PXF49527.1 - 0.11 12.6 1.6 0.18 11.9 1.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain FANCL_C PF11793.8 PXF49527.1 - 0.14 12.4 7.8 3.1 8.1 7.8 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PXF49527.1 - 0.14 11.8 8.5 0.29 10.8 8.5 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type UBZ_FAAP20 PF15750.5 PXF49527.1 - 0.31 11.0 6.3 6.8 6.7 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger YdjO PF14169.6 PXF49527.1 - 0.31 10.8 4.4 9.9 6.0 0.2 2.6 3 0 0 3 3 2 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 PXF49527.1 - 0.39 10.6 9.0 0.69 9.8 9.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YacG PF03884.14 PXF49527.1 - 0.64 9.8 7.1 1.8 8.4 0.7 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Rad50_zn_hook PF04423.14 PXF49527.1 - 0.72 9.7 7.4 2.9 7.8 4.1 2.8 2 1 0 2 2 2 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 PXF49527.1 - 0.8 10.2 10.4 1.4 9.4 0.1 3.3 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 PXF49527.1 - 0.93 9.5 6.9 7 6.7 0.9 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Tmpp129 PF10272.9 PXF49527.1 - 1.1 8.4 6.6 0.09 12.1 1.9 1.4 2 0 0 2 2 2 0 Putative transmembrane protein precursor zinc_ribbon_16 PF17034.5 PXF49527.1 - 2.1 8.6 8.0 0.78 10.0 3.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon like family GAGA PF09237.11 PXF49527.1 - 2.4 8.0 7.0 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 GAGA factor UPF0547 PF10571.9 PXF49527.1 - 2.4 8.3 8.2 1.7 8.8 0.1 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF4112 PF13430.6 PXF49528.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) DUF1523 PF07509.11 PXF49529.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) DUF4164 PF13747.6 PXF49529.1 - 0.11 12.8 1.2 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cob_adeno_trans PF01923.18 PXF49529.1 - 0.14 12.3 1.3 0.22 11.7 1.3 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Peptidase_M17 PF00883.21 PXF49530.1 - 6.1e-113 377.2 4.2 6.1e-113 377.2 4.2 1.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 PXF49530.1 - 1.3e-11 44.5 0.3 3.6e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Pkinase PF00069.25 PXF49532.1 - 1.4e-66 224.5 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49532.1 - 9.2e-31 107.0 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49532.1 - 4.8e-08 32.7 0.0 1.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PXF49532.1 - 8.8e-06 24.7 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PXF49532.1 - 0.0035 16.4 0.1 0.0048 15.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PXF49532.1 - 0.015 15.2 0.4 0.037 13.9 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PXF49532.1 - 0.016 14.8 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PXF49532.1 - 0.03 13.9 0.0 8.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RSF PF14876.6 PXF49532.1 - 0.11 11.4 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Kdo PF06293.14 PXF49532.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mlf1IP PF10248.9 PXF49533.1 - 4.8e-07 29.9 2.7 1.8e-06 28.1 2.7 1.9 1 1 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Phosphodiest PF01663.22 PXF49534.1 - 2.1e-70 238.1 1.6 2.7e-70 237.7 1.5 1.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 PXF49534.1 - 1.5e-06 27.8 0.3 3.2e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 PXF49534.1 - 8.4e-05 22.1 0.9 0.0087 15.5 0.2 2.8 2 1 0 2 2 2 1 Sulfatase PglZ PF08665.12 PXF49534.1 - 0.00016 21.8 0.2 0.0011 19.1 0.0 2.4 3 0 0 3 3 3 1 PglZ domain DUF1501 PF07394.12 PXF49534.1 - 0.0033 16.6 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) TGS PF02824.21 PXF49534.1 - 0.15 12.2 0.3 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 TGS domain COX7a PF02238.15 PXF49534.1 - 2.9 8.4 4.7 18 5.8 0.7 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII GST_N_2 PF13409.6 PXF49535.1 - 1.9e-20 73.0 0.0 3.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF49535.1 - 7.1e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PXF49535.1 - 2.1e-09 37.5 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF49535.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PXF49535.1 - 4.5e-05 23.8 0.0 0.0011 19.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Arc PF03869.14 PXF49535.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Arc-like DNA binding domain PI3_PI4_kinase PF00454.27 PXF49536.1 - 3.7e-51 174.4 0.3 1.1e-50 172.8 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PXF49536.1 - 4.7e-07 29.5 0.0 1.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 PXF49536.1 - 0.00086 19.4 0.4 12 6.5 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat EMP24_GP25L PF01105.24 PXF49537.1 - 3.1e-16 59.8 0.1 4.2e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RAI1 PF08652.11 PXF49538.1 - 1.8e-16 60.1 0.0 3.6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease TLD PF07534.16 PXF49540.1 - 1.1e-35 122.9 0.2 1.4e-35 122.6 0.2 1.1 1 0 0 1 1 1 1 TLD Globin PF00042.22 PXF49541.1 - 3.5e-10 40.4 0.0 6.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Globin Cation_efflux PF01545.21 PXF49542.1 - 1.3e-20 74.0 6.9 1.6e-20 73.7 6.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PXF49542.1 - 1.2e-10 41.4 0.1 2.3e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF3180 PF11377.8 PXF49542.1 - 0.3 11.2 4.0 0.28 11.3 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) tRNA_U5-meth_tr PF05958.11 PXF49543.1 - 2.9e-06 26.5 0.0 6.7e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 PXF49543.1 - 0.00049 19.7 0.0 0.00076 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain zinc_ribbon_4 PF13717.6 PXF49543.1 - 0.09 12.7 0.1 0.3 11.0 0.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Metallophos PF00149.28 PXF49544.1 - 9.3e-39 134.0 0.2 1.2e-38 133.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PXF49544.1 - 5e-18 65.3 1.5 9.2e-18 64.4 1.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Vps26 PF03643.15 PXF49545.1 - 2.9e-101 338.1 1.9 3.4e-101 337.9 1.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 HOOK PF05622.12 PXF49547.1 - 0.00029 19.2 1.0 0.15 10.2 1.0 2.5 2 1 0 2 2 2 2 HOOK protein Rootletin PF15035.6 PXF49547.1 - 0.057 13.4 1.4 0.097 12.7 1.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HSCB_C PF07743.13 PXF49547.1 - 0.19 12.2 1.2 2.7 8.6 0.3 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain ATG16 PF08614.11 PXF49547.1 - 1.9 8.7 5.8 0.15 12.3 0.9 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 PXF49547.1 - 2.9 7.7 4.0 19 5.1 0.1 2.3 1 1 0 2 2 2 0 Septum formation initiator Actin PF00022.19 PXF49548.1 - 2.8e-135 451.1 0.0 1.3e-134 448.9 0.0 1.8 1 1 0 1 1 1 1 Actin DUF1746 PF08508.10 PXF49549.1 - 6e-05 23.4 2.8 0.00011 22.6 2.8 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) mTERF PF02536.14 PXF49550.1 - 6.1e-44 150.2 0.0 6e-37 127.2 0.0 3.0 1 1 1 2 2 2 2 mTERF ARID PF01388.21 PXF49551.1 - 3.1e-11 43.8 0.0 5.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 PXF49551.1 - 0.13 11.5 0.2 0.3 10.3 0.1 1.6 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa zf-BED PF02892.15 PXF49552.1 - 0.18 11.8 2.3 0.53 10.4 0.7 2.4 2 0 0 2 2 2 0 BED zinc finger FOXP-CC PF16159.5 PXF49552.1 - 0.86 10.3 4.0 3.5 8.3 0.2 3.0 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF4379 PF14311.6 PXF49552.1 - 1.6 9.2 7.2 4.3 7.8 0.9 2.8 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-C2H2_4 PF13894.6 PXF49552.1 - 2.9 9.0 15.5 8.2 7.6 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger His_Phos_1 PF00300.22 PXF49553.1 - 2.5e-19 69.8 0.4 8.5e-13 48.4 0.3 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SKA2 PF16740.5 PXF49555.1 - 0.067 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 LIN52 PF10044.9 PXF49555.1 - 0.085 13.6 0.0 0.38 11.5 0.0 2.2 2 0 0 2 2 2 0 Retinal tissue protein DUF3348 PF11828.8 PXF49555.1 - 0.14 11.8 0.7 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) Helicase_C PF00271.31 PXF49556.1 - 4.4e-17 62.4 0.0 2.2e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PXF49556.1 - 1.9e-11 44.5 3.6 1.9e-11 44.5 3.6 2.8 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 PXF49556.1 - 0.00079 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_1 PF00515.28 PXF49558.1 - 2.4e-14 52.4 5.3 0.003 17.3 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 PXF49558.1 - 4.7e-12 45.9 1.6 0.002 18.2 0.0 4.4 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49558.1 - 2.6e-09 36.5 18.4 0.003 17.5 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49558.1 - 1.5e-08 35.1 11.9 0.013 16.0 0.6 7.6 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 PXF49558.1 - 0.00012 22.6 12.5 2 9.4 0.7 8.8 6 2 4 10 10 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49558.1 - 0.00016 21.9 17.3 0.022 15.0 0.1 5.3 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49558.1 - 0.00025 21.0 10.8 0.011 15.9 0.9 6.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49558.1 - 0.00031 21.3 21.3 0.045 14.4 0.6 7.7 7 2 4 11 11 10 4 Tetratricopeptide repeat NARP1 PF12569.8 PXF49558.1 - 0.0012 17.8 0.2 0.18 10.7 0.1 2.6 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 PXF49558.1 - 0.0014 18.5 5.9 2.5 8.3 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF49558.1 - 0.0018 18.5 5.9 1.5 9.1 0.0 6.3 6 1 3 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PXF49558.1 - 0.0022 18.5 8.9 6 7.7 0.0 7.3 9 0 0 9 9 7 1 Tetratricopeptide repeat SNAP PF14938.6 PXF49558.1 - 0.056 12.9 1.1 0.85 9.0 0.5 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 PXF49558.1 - 0.065 12.9 12.5 0.086 12.5 0.0 5.2 5 2 2 7 7 7 0 TPR repeat TPR_17 PF13431.6 PXF49558.1 - 0.092 13.2 5.9 6.3 7.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat YL1 PF05764.13 PXF49558.1 - 0.16 12.1 15.5 0.28 11.3 6.4 3.0 2 1 0 2 2 2 0 YL1 nuclear protein MIT PF04212.18 PXF49558.1 - 3.5 7.8 6.2 3.1 7.9 0.3 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain PK PF00224.21 PXF49559.1 - 2e-107 359.1 2.2 2.8e-107 358.6 2.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PXF49559.1 - 5.1e-27 94.4 0.0 1.2e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 PXF49559.1 - 0.043 12.8 0.1 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain GEMIN8 PF15348.6 PXF49560.1 - 3e-07 31.0 0.3 1.1e-06 29.2 0.0 1.8 1 1 1 2 2 2 1 Gemini of Cajal bodies-associated protein 8 Alpha_kinase PF02816.18 PXF49561.1 - 1.2e-13 51.6 0.0 1.3e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family Sel1 PF08238.12 PXF49562.1 - 2.5e-30 104.2 15.0 4.4e-06 27.2 0.0 8.7 8 0 0 8 8 8 8 Sel1 repeat Fis1_TPR_N PF14852.6 PXF49562.1 - 0.0033 17.1 0.6 0.21 11.3 0.3 3.6 3 0 0 3 3 3 1 Fis1 N-terminal tetratricopeptide repeat Rieske PF00355.26 PXF49563.1 - 2.9e-08 33.5 0.1 4.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PXF49563.1 - 0.0039 17.1 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain GSDH PF07995.11 PXF49564.1 - 7.9e-21 74.7 0.0 2.7e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF839 PF05787.13 PXF49564.1 - 0.03 13.5 0.0 0.08 12.1 0.0 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF839) Coatomer_WDAD PF04053.14 PXF49567.1 - 3.8e-05 22.9 0.0 5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region DDE_Tnp_4 PF13359.6 PXF49568.1 - 2.4e-09 37.1 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Spond_N PF06468.13 PXF49569.1 - 9.3e-09 35.7 0.0 1.1e-08 35.5 0.0 1.0 1 0 0 1 1 1 1 Spondin_N Acetyltransf_10 PF13673.7 PXF49570.1 - 8.7e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PXF49570.1 - 0.00019 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PXF49570.1 - 0.00027 21.3 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gemin7 PF11095.8 PXF49575.1 - 0.059 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) MMS1_N PF10433.9 PXF49579.1 - 4.3e-97 325.8 0.0 6.4e-97 325.2 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PXF49579.1 - 6.9e-50 170.2 0.0 1.7e-47 162.3 0.0 3.0 2 1 0 2 2 2 2 CPSF A subunit region Branch PF02485.21 PXF49580.1 - 3.3e-30 105.4 0.5 5.8e-30 104.6 0.5 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme S1 PF00575.23 PXF49581.1 - 3e-12 46.7 0.2 1.1e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 PXF49581.1 - 0.13 12.7 0.1 0.35 11.3 0.1 1.8 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_S5 PF00333.20 PXF49582.1 - 5.3e-29 100.0 2.0 9.3e-29 99.2 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PXF49582.1 - 9.5e-24 82.6 0.1 1.8e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain XRN_N PF03159.18 PXF49583.1 - 6.3e-39 133.8 0.0 9.5e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PXF49583.1 - 0.0041 16.1 1.7 0.083 11.8 1.7 2.3 1 1 0 1 1 1 1 Xrn1 helical domain XPG_N PF00752.17 PXF49583.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain DAGK_acc PF00609.19 PXF49584.1 - 2.4e-34 119.0 0.0 6.3e-34 117.6 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PXF49584.1 - 1.9e-21 76.0 0.0 3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 PXF49585.1 - 9.7e-52 175.9 0.0 2.7e-47 161.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49585.1 - 1e-50 172.4 0.0 2.5e-45 154.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Plant_tran PF04827.14 PXF49586.1 - 7.9e-38 130.1 0.0 1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF49586.1 - 1.6e-08 34.3 0.0 2.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cactin_mid PF10312.9 PXF49587.1 - 0.017 14.9 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin DUF3684 PF12449.8 PXF49589.1 - 3e-18 65.1 0.0 3.7e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) SRF-TF PF00319.18 PXF49590.1 - 2.8e-22 77.9 0.1 4.6e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HalX PF08663.10 PXF49591.1 - 0.0056 17.0 1.0 0.0056 17.0 1.0 1.9 2 1 0 2 2 2 1 HalX domain CLZ PF16526.5 PXF49591.1 - 0.1 13.0 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GIT_CC PF16559.5 PXF49591.1 - 0.14 12.1 2.9 0.31 10.9 0.1 2.3 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRTP PF01366.18 PXF49591.1 - 0.15 10.1 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein UbiA PF01040.18 PXF49591.1 - 0.15 11.3 9.4 0.25 10.6 9.4 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family SBF PF01758.16 PXF49592.1 - 1.8e-36 125.7 16.1 1.8e-36 125.7 16.1 1.4 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 PXF49592.1 - 2.4e-11 43.5 21.3 3.8e-11 42.9 21.3 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Clat_adaptor_s PF01217.20 PXF49593.1 - 2.5e-48 163.6 1.3 2.9e-48 163.4 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MAGE PF01454.19 PXF49595.1 - 7e-21 74.9 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 MAGE family Gluconate_2-dh3 PF13618.6 PXF49595.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 IATP PF04568.12 PXF49597.1 - 8.6e-07 29.3 2.9 1.6e-06 28.5 2.9 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2001 PF09393.10 PXF49597.1 - 0.03 14.3 0.1 0.35 10.9 0.0 1.9 1 1 1 2 2 2 0 Phage tail tube protein Spore_III_AB PF09548.10 PXF49597.1 - 0.12 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_M20 PF01546.28 PXF49599.1 - 1.1e-22 80.8 0.0 2e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PXF49599.1 - 9.4e-12 44.8 0.0 1.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain GATase_6 PF13522.6 PXF49599.1 - 8.7e-09 35.7 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.32 PXF49599.1 - 3.6e-08 33.9 18.2 0.054 14.4 0.3 5.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Hira PF07569.11 PXF49599.1 - 0.0013 18.5 1.4 0.19 11.4 0.1 3.1 3 0 0 3 3 3 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 PXF49599.1 - 0.011 16.0 0.1 1.9 8.9 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PXF49599.1 - 0.054 12.1 0.1 0.11 11.1 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40_like PF17005.5 PXF49599.1 - 0.064 12.6 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PDZ PF00595.24 PXF49600.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF1475 PF07343.11 PXF49601.1 - 3.5e-05 23.8 0.6 3.5e-05 23.8 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1475) DUF5336 PF17270.2 PXF49601.1 - 0.038 13.6 0.6 0.038 13.6 0.6 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5336) DUF2530 PF10745.9 PXF49601.1 - 1.1 9.6 10.3 4.2 7.7 0.1 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2530) FA_desaturase PF00487.24 PXF49602.1 - 2.2e-33 116.2 24.7 2.2e-33 116.2 24.7 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 PXF49602.1 - 0.00067 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) XG_FTase PF03254.13 PXF49607.1 - 0.014 14.0 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase TTR-52 PF01060.23 PXF49609.1 - 0.088 13.5 0.3 13 6.6 0.0 3.0 2 1 1 3 3 3 0 Transthyretin-like family TIP49_C PF17856.1 PXF49611.1 - 0.017 15.3 0.4 0.1 12.7 0.0 2.3 2 1 1 3 3 3 0 TIP49 AAA-lid domain Peptidase_S8 PF00082.22 PXF49612.1 - 1e-21 77.5 6.4 2e-21 76.5 4.1 2.2 2 1 0 2 2 2 1 Subtilase family Fumerase_C PF05683.12 PXF49620.1 - 0.049 13.0 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Fumarase C-terminus PBP_sp32 PF07222.12 PXF49620.1 - 0.063 12.7 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_C14 PF00656.22 PXF49621.1 - 2.7e-38 132.3 0.0 3.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF1539 PF07560.11 PXF49623.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) YceD PF02620.17 PXF49624.1 - 0.001 19.2 2.1 0.0017 18.4 2.1 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD XRN_N PF03159.18 PXF49624.1 - 0.26 10.7 1.9 0.93 8.9 2.8 1.7 2 1 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus CDC45 PF02724.14 PXF49624.1 - 1.7 6.8 6.7 1.9 6.7 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein MPP6 PF10175.9 PXF49624.1 - 6.1 7.4 8.8 1.2 9.6 5.2 1.7 1 1 0 1 1 1 0 M-phase phosphoprotein 6 DUF1380 PF07128.12 PXF49625.1 - 0.031 14.5 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Trans_reg_C PF00486.28 PXF49625.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Oxidored_q2 PF00420.24 PXF49626.1 - 0.05 13.2 0.1 0.05 13.2 0.1 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MIG-14_Wnt-bd PF06664.12 PXF49626.1 - 0.16 11.1 6.3 0.33 10.1 0.5 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion LRR19-TM PF15176.6 PXF49626.1 - 0.25 11.3 1.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain zf-C2H2 PF00096.26 PXF49627.1 - 1.3e-12 47.4 27.0 0.0003 21.1 1.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PXF49627.1 - 4.8e-12 45.6 24.9 0.0064 17.2 0.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PXF49627.1 - 1.1e-08 35.1 7.9 3.9e-06 27.0 0.4 4.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_11 PF16622.5 PXF49627.1 - 6.4e-05 22.6 16.1 0.0036 17.0 0.6 4.4 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 PXF49627.1 - 0.00011 22.4 13.9 0.0058 16.9 1.2 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 PXF49627.1 - 0.069 13.6 23.1 0.072 13.5 1.8 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 PXF49627.1 - 0.11 13.1 16.8 68 4.1 8.3 3.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 PXF49627.1 - 0.14 12.2 0.5 0.14 12.2 0.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 PXF49627.1 - 0.18 11.9 11.4 3.2 7.9 0.5 3.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger PyrI_C PF02748.15 PXF49627.1 - 0.85 9.6 9.8 0.75 9.7 0.7 3.2 1 1 2 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 PXF49627.1 - 1.1 10.1 12.9 0.86 10.4 5.8 2.3 1 1 1 2 2 2 0 zinc-ribbon family MerB PF03243.15 PXF49630.1 - 1.7e-05 25.0 2.5 4.2 7.5 0.0 4.1 4 0 0 4 4 4 3 Alkylmercury lyase Utp12 PF04003.12 PXF49630.1 - 0.061 13.6 13.7 3.4 8.0 0.3 4.3 1 1 3 4 4 4 0 Dip2/Utp12 Family HEAT PF02985.22 PXF49632.1 - 1.5e-06 27.9 0.3 0.5 10.8 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 PXF49632.1 - 8.3e-06 26.1 0.2 0.00026 21.3 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 PXF49632.1 - 0.00023 21.2 1.1 0.0012 18.9 1.2 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 PXF49632.1 - 0.0078 16.2 0.0 0.04 13.9 0.0 2.1 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus SMG1 PF15785.5 PXF49632.1 - 0.026 12.9 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Adaptin_N PF01602.20 PXF49632.1 - 0.036 12.6 0.1 0.049 12.2 0.1 1.1 1 0 0 1 1 1 0 Adaptin N terminal region DUF4042 PF13251.6 PXF49632.1 - 0.063 13.0 0.1 12 5.5 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4042) MMS22L_C PF14911.6 PXF49632.1 - 0.19 10.8 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal STAG PF08514.11 PXF49633.1 - 1.8e-10 40.7 0.0 2.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 STAG domain bZIP_2 PF07716.15 PXF49634.1 - 1.1e-05 25.4 12.9 1.7e-05 24.8 12.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 PXF49634.1 - 0.0034 17.5 13.4 0.0073 16.4 13.4 1.5 1 1 0 1 1 1 1 bZIP transcription factor Phlebovirus_NSM PF07246.11 PXF49634.1 - 0.034 13.5 0.8 0.047 13.1 0.8 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M bZIP_Maf PF03131.17 PXF49634.1 - 0.045 14.3 4.9 0.077 13.5 4.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 PXF49634.1 - 0.51 8.8 7.3 0.7 8.4 7.3 1.1 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 PXF49634.1 - 1.6 7.7 8.8 2 7.4 8.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X VWD PF00094.25 PXF49635.1 - 0.029 14.6 0.5 0.091 13.0 0.5 1.8 1 1 0 1 1 1 0 von Willebrand factor type D domain Mannitol_dh PF01232.23 PXF49637.1 - 3.3e-36 124.7 0.0 3.9e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain HDAC4_Gln PF12203.8 PXF49638.1 - 0.026 14.7 2.2 0.026 14.7 2.2 2.0 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Mating_C PF12737.7 PXF49638.1 - 0.19 10.9 2.8 0.2 10.8 2.8 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 EzrA PF06160.12 PXF49640.1 - 0.018 13.3 1.8 0.024 12.8 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF49640.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF49640.1 - 4.6 7.9 13.5 0.76 10.5 6.5 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Ephrin_rec_like PF07699.13 PXF49641.1 - 3.5e-43 145.1 173.3 4.2e-07 29.6 7.7 17.1 5 4 13 18 18 18 18 Putative ephrin-receptor like NCD3G PF07562.14 PXF49641.1 - 1.3e-17 63.5 141.2 0.012 15.6 4.9 16.6 13 4 1 16 16 16 14 Nine Cysteines Domain of family 3 GPCR DUF4423 PF14394.6 PXF49644.1 - 0.03 14.0 0.1 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) peroxidase PF00141.23 PXF49645.1 - 3.9e-40 137.9 0.0 1.5e-39 136.0 0.0 1.8 1 1 0 1 1 1 1 Peroxidase GGDEF_2 PF17853.1 PXF49647.1 - 0.092 13.0 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 GGDEF-like domain SOG2 PF10428.9 PXF49651.1 - 0.062 12.5 1.0 0.069 12.3 1.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein VPS13 PF16908.5 PXF49652.1 - 1.1e-05 25.3 0.1 1.4e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal NAD_binding_8 PF13450.6 PXF49653.1 - 4.4e-14 52.5 0.3 1.7e-11 44.2 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PXF49653.1 - 1.6e-13 50.8 0.0 2.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 PXF49653.1 - 1.7e-06 27.8 4.2 0.0023 17.6 1.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PXF49653.1 - 2.9e-05 24.1 2.0 0.019 15.0 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 PXF49653.1 - 0.0042 15.8 0.3 0.32 9.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 PXF49653.1 - 0.0063 15.8 1.0 1.2 8.3 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GAS PF13851.6 PXF49654.1 - 0.0038 16.6 28.2 0.035 13.5 13.3 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 PXF49654.1 - 0.0073 16.1 6.4 0.0073 16.1 6.4 2.6 2 1 1 3 3 3 1 Phage minor structural protein GP20 SlyX PF04102.12 PXF49654.1 - 0.016 15.8 2.2 0.016 15.8 2.2 3.5 2 1 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.9 PXF49654.1 - 0.017 15.3 27.1 0.028 14.7 3.4 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 PXF49654.1 - 0.021 14.9 22.9 0.15 12.1 3.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 PXF49654.1 - 0.026 14.6 12.0 0.12 12.4 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 PXF49654.1 - 0.034 14.4 13.7 0.043 14.1 3.9 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 PXF49654.1 - 0.054 14.2 12.9 1.4 9.7 0.3 3.3 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.9 PXF49654.1 - 0.088 12.8 21.6 0.46 10.5 14.8 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps53_N PF04100.12 PXF49654.1 - 0.095 11.6 11.0 0.042 12.8 8.4 1.6 1 1 1 2 2 2 0 Vps53-like, N-terminal Fib_alpha PF08702.10 PXF49654.1 - 0.12 12.6 16.0 0.68 10.1 5.8 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 PXF49654.1 - 0.16 10.6 18.5 0.23 10.1 18.5 1.1 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 PXF49654.1 - 0.17 12.3 8.7 1.9 9.0 0.7 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 PXF49654.1 - 0.23 11.7 11.1 4.1 7.7 1.8 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Spore_III_AB PF09548.10 PXF49654.1 - 0.23 11.5 7.9 6.6 6.8 7.9 2.2 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HOOK PF05622.12 PXF49654.1 - 0.32 9.1 23.6 4.2 5.4 5.1 2.4 1 1 1 2 2 2 0 HOOK protein DUF2730 PF10805.8 PXF49654.1 - 0.46 10.6 9.9 0.11 12.5 2.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) MAD PF05557.13 PXF49654.1 - 0.56 8.5 25.9 1.4 7.2 25.9 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF745 PF05335.13 PXF49654.1 - 0.74 9.5 26.7 0.96 9.1 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 PXF49654.1 - 0.75 9.1 22.8 0.27 10.5 7.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) T3SSipB PF16535.5 PXF49654.1 - 0.83 10.1 22.9 0.19 12.2 8.8 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB DASH_Dam1 PF08653.10 PXF49654.1 - 1 9.2 3.5 20 5.1 0.1 2.8 3 0 0 3 3 2 0 DASH complex subunit Dam1 DUF16 PF01519.16 PXF49654.1 - 1.3 9.6 14.0 5.2 7.6 6.0 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 PXF49654.1 - 1.3 9.0 29.5 2.4 8.2 16.1 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein YkyA PF10368.9 PXF49654.1 - 1.9 8.1 18.3 0.67 9.6 7.6 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein APG6_N PF17675.1 PXF49654.1 - 2.2 8.8 30.8 3.7 8.1 9.2 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 PXF49654.1 - 3 8.0 35.7 0.93 9.7 27.7 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 PXF49654.1 - 3.3 8.1 26.2 25 5.3 12.0 2.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 PXF49654.1 - 3.7 7.6 22.4 0.41 10.7 7.3 2.4 1 1 1 2 2 2 0 Laminin Domain II HrpB7 PF09486.10 PXF49654.1 - 5.3 7.4 27.0 5.9 7.3 7.2 3.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.11 PXF49654.1 - 5.6 7.6 15.6 2.1e+03 -0.7 15.6 3.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal BRE1 PF08647.11 PXF49654.1 - 6.9 6.8 24.7 1.3 9.2 11.1 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 PXF49654.1 - 6.9 6.9 22.3 1.4 9.1 14.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 PXF49654.1 - 7.2 4.0 26.7 1.1 6.7 7.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DivIC PF04977.15 PXF49654.1 - 9.7 6.0 24.7 6 6.7 3.8 4.0 2 1 1 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 PXF49655.1 - 1.7e-09 37.6 9.8 5e-09 36.1 9.8 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF49655.1 - 5.8e-08 32.7 10.3 1.7e-07 31.2 10.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper ubiquitin PF00240.23 PXF49655.1 - 3.3e-07 30.0 0.0 7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PXF49655.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 PXF49655.1 - 0.0032 17.6 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HHH_9 PF17674.1 PXF49655.1 - 0.18 12.8 0.8 1.7 9.6 0.0 3.1 4 0 0 4 4 4 0 HHH domain bZIP_Maf PF03131.17 PXF49655.1 - 0.59 10.7 8.6 1.5 9.4 8.6 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 PXF49655.1 - 4.7 5.6 12.9 7.1 5.1 12.9 1.2 1 0 0 1 1 1 0 Macoilin family DnaJ_C PF01556.18 PXF49656.1 - 5.8e-31 107.6 0.0 8.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PXF49656.1 - 2.3e-21 75.7 1.1 3.7e-21 75.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PXF49656.1 - 3.9e-11 43.2 14.3 7.3e-11 42.3 14.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PXF49656.1 - 4.8e-06 26.4 14.7 0.00031 20.6 3.3 2.8 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 PXF49656.1 - 2.7 8.3 16.5 11 6.3 0.6 4.9 5 0 0 5 5 5 0 Family of unknown function (DUF5351) PAH PF02671.21 PXF49657.1 - 1.2e-30 105.4 9.9 7.8e-16 57.9 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 PXF49657.1 - 5.7e-21 75.5 0.1 5.7e-21 75.5 0.1 2.8 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 PXF49657.1 - 2e-10 40.6 0.4 5.7e-10 39.2 0.4 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Sld5 PF05916.11 PXF49660.1 - 5.4e-08 33.3 0.0 7.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein tRNA-synt_1 PF00133.22 PXF49661.1 - 1e-57 195.8 8.9 7.8e-41 140.0 3.7 5.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 PXF49661.1 - 9.5e-52 175.2 0.0 1.5e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 PXF49661.1 - 4e-25 88.4 0.0 6.5e-17 61.3 0.0 3.6 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PXF49661.1 - 3.1e-16 59.7 0.4 1.8e-15 57.2 0.4 2.1 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PXF49661.1 - 0.0014 18.0 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PXF49661.1 - 0.024 13.6 0.0 0.075 11.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) MCM_bind PF09739.9 PXF49662.1 - 6.3e-89 299.0 0.0 2.5e-88 297.0 0.0 1.7 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM PF00493.23 PXF49663.1 - 8.7e-74 247.4 1.7 5.7e-62 208.7 0.1 2.3 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 PXF49663.1 - 9.7e-29 99.8 0.0 3.5e-28 98.0 0.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 PXF49663.1 - 7.8e-22 77.5 1.9 4.3e-21 75.1 2.9 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PXF49663.1 - 2.3e-08 34.6 0.1 1.4e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PXF49663.1 - 0.0029 17.0 0.0 0.071 12.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PBP1_TM PF14812.6 PXF49663.1 - 3.7 8.0 10.0 16 6.0 10.0 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Castor_Poll_mid PF06241.12 PXF49666.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Bax1-I PF01027.20 PXF49667.1 - 4e-48 164.0 36.3 4.6e-48 163.8 36.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Per1 PF04080.13 PXF49667.1 - 7.8 6.2 9.0 5.2 6.7 7.4 1.5 1 1 0 1 1 1 0 Per1-like family SAS-6_N PF16531.5 PXF49668.1 - 3.5e-09 37.1 0.0 2.6e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 Centriolar protein SAS N-terminal ATG16 PF08614.11 PXF49668.1 - 0.0016 18.7 39.5 0.17 12.1 4.7 3.3 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 PXF49668.1 - 0.0096 14.8 30.6 0.013 14.4 30.6 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 PXF49668.1 - 0.011 16.0 18.8 0.028 14.7 1.4 4.0 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 PXF49668.1 - 0.013 15.6 23.0 0.013 15.6 23.0 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 PXF49668.1 - 0.11 11.4 32.3 0.75 8.6 24.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein TFIIA PF03153.13 PXF49668.1 - 0.2 11.7 21.1 0.24 11.4 21.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phage_GP20 PF06810.11 PXF49668.1 - 0.22 11.3 18.5 0.29 10.9 2.1 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3584 PF12128.8 PXF49668.1 - 0.22 9.0 30.4 0.31 8.5 30.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 PXF49668.1 - 0.26 10.6 33.6 0.011 15.0 18.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 PXF49668.1 - 0.49 9.4 35.4 0.07 12.2 20.2 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 PXF49668.1 - 0.54 10.3 23.4 0.19 11.8 7.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 PXF49668.1 - 0.56 9.6 30.7 0.2 11.1 27.5 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 PXF49668.1 - 0.96 9.1 40.7 1.7 8.3 9.7 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease LMBR1 PF04791.16 PXF49668.1 - 1.5 7.6 10.2 2.1 7.2 10.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein XhlA PF10779.9 PXF49668.1 - 1.8 8.8 11.4 5 7.4 2.4 2.9 3 0 0 3 3 2 0 Haemolysin XhlA TMF_TATA_bd PF12325.8 PXF49668.1 - 2.3 8.5 31.8 1.3 9.3 8.5 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 PXF49668.1 - 4.5 7.3 42.7 5.9 7.0 15.5 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding HemX PF04375.14 PXF49668.1 - 5.4 6.2 41.3 0.18 11.1 17.2 3.3 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase HlyD_2 PF12700.7 PXF49668.1 - 7.1 5.3 20.3 2 7.0 1.6 3.0 1 1 2 3 3 3 0 HlyD family secretion protein DUF4407 PF14362.6 PXF49668.1 - 7.8 5.8 32.4 8.1 5.7 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Pro_isomerase PF00160.21 PXF49670.1 - 4e-53 179.9 0.1 6.3e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 PXF49670.1 - 0.053 14.4 0.2 1.4 9.9 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat SUIM_assoc PF16619.5 PXF49670.1 - 0.13 12.3 4.1 0.093 12.8 0.5 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cyclin PF08613.11 PXF49671.1 - 3.9e-33 115.1 0.2 3.9e-33 115.1 0.2 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PXF49671.1 - 7.8e-07 28.9 0.4 1.4e-06 28.1 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain G_path_suppress PF15991.5 PXF49672.1 - 0.0026 17.9 1.2 0.0038 17.4 1.2 1.3 1 0 0 1 1 1 1 G-protein pathway suppressor VPS11_C PF12451.8 PXF49672.1 - 0.15 12.3 0.6 0.43 10.9 0.6 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal bZIP_1 PF00170.21 PXF49673.1 - 1.5e-07 31.4 9.8 6.4e-07 29.4 9.8 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PXF49673.1 - 0.00034 20.6 13.6 0.0031 17.5 13.6 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PXF49673.1 - 0.015 15.8 4.6 0.027 15.0 4.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 PXF49673.1 - 0.21 12.2 1.0 0.77 10.4 0.1 1.9 1 1 1 2 2 2 0 Initiation control protein YabA tRNA-synt_1b PF00579.25 PXF49675.1 - 3.3e-79 266.3 0.0 4.7e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 PXF49675.1 - 0.0092 15.7 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 S4 domain Acetyltransf_6 PF13480.7 PXF49675.1 - 0.11 12.7 0.2 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ATE_C PF04377.15 PXF49675.1 - 0.13 12.9 0.0 2.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus DUF568 PF04526.13 PXF49676.1 - 0.092 13.5 0.5 0.092 13.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF568) Nup54 PF13874.6 PXF49677.1 - 1.5e-30 106.1 1.0 2.4e-30 105.5 1.0 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 BLYB PF05289.11 PXF49677.1 - 0.043 14.0 0.5 0.09 13.0 0.5 1.5 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein BBP1_C PF15272.6 PXF49677.1 - 0.073 12.9 0.5 0.12 12.2 0.5 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal RXLR PF16810.5 PXF49678.1 - 0.17 12.3 5.9 0.48 10.9 2.1 2.3 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Thioredoxin PF00085.20 PXF49680.1 - 4.7e-11 42.6 0.0 9.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HAD_2 PF13419.6 PXF49681.1 - 9.2e-17 61.7 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF49681.1 - 3.6e-10 40.5 0.0 4.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF49681.1 - 5.2e-06 26.4 0.0 9.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PXF49681.1 - 0.0025 18.3 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PEP-utilizers_C PF02896.18 PXF49681.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Arm PF00514.23 PXF49682.1 - 1.4e-05 24.9 0.7 0.015 15.4 0.1 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 PXF49682.1 - 0.063 13.3 0.4 9 6.4 0.0 3.4 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DUF3177 PF11375.8 PXF49683.1 - 0.0021 17.9 12.3 0.012 15.4 12.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3177) Swi3 PF07962.12 PXF49684.1 - 3.3e-06 27.0 0.0 3.5e-05 23.7 0.0 2.2 1 1 1 2 2 2 1 Replication Fork Protection Component Swi3 DUF3106 PF11304.8 PXF49685.1 - 0.081 13.4 1.6 0.45 11.0 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Maf PF02545.14 PXF49686.1 - 5.1e-58 195.6 0.0 5.8e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Pentapeptide PF00805.22 PXF49687.1 - 3.2e-14 52.2 2.9 4.1e-07 29.5 1.0 2.4 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PXF49687.1 - 6.7e-10 39.0 0.2 2.5e-09 37.1 0.2 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PXF49687.1 - 3e-07 30.5 6.7 0.0003 20.9 2.1 2.8 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Myb_DNA-binding PF00249.31 PXF49688.1 - 9.9e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PXF49688.1 - 0.0031 17.4 0.2 0.0056 16.5 0.2 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PXF49688.1 - 0.048 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain ThrE PF06738.12 PXF49688.1 - 0.053 12.9 0.9 0.072 12.4 0.1 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter Hint PF01079.20 PXF49689.1 - 3e-25 89.0 0.2 6.6e-25 87.9 0.2 1.5 1 1 0 1 1 1 1 Hint module Prenylcys_lyase PF07156.14 PXF49693.1 - 4.4e-07 29.4 0.0 0.0003 20.0 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.6 PXF49693.1 - 0.002 18.3 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF49693.1 - 0.0039 16.8 0.0 0.78 9.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PXF49693.1 - 0.0052 16.1 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 PXF49693.1 - 0.02 14.9 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding F-box-like PF12937.7 PXF49694.1 - 1.9e-13 50.1 0.6 3.8e-13 49.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PXF49694.1 - 2e-05 24.3 0.6 4.2e-05 23.3 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PXF49694.1 - 0.025 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 F-box Cyclin PF08613.11 PXF49695.1 - 9.9e-29 100.8 0.0 1.4e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF49695.1 - 2.4e-07 30.5 0.5 4.3e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sulfotransfer_2 PF03567.14 PXF49701.1 - 1.5e-07 31.6 0.0 1.1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PXF49701.1 - 0.00016 21.2 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Gal-3-0_sulfotr PF06990.11 PXF49701.1 - 0.019 13.9 5.6 0.1 11.4 5.6 1.9 1 1 0 1 1 1 0 Galactose-3-O-sulfotransferase DUF1623 PF07785.11 PXF49703.1 - 0.15 12.3 0.3 1 9.6 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1623) Clp_N PF02861.20 PXF49707.1 - 0.24 11.6 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component DEC-1_N PF04625.13 PXF49707.1 - 4.5 6.2 9.6 4.6 6.2 9.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Tox-REase-2 PF15646.6 PXF49708.1 - 0.072 13.3 0.1 0.095 12.9 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 ATG16 PF08614.11 PXF49708.1 - 0.18 12.0 5.2 3.4 7.8 5.7 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4558 PF15104.6 PXF49708.1 - 0.27 11.3 2.8 18 5.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) DUF3734 PF12536.8 PXF49710.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Patatin phospholipase Ribosomal_L12_N PF16320.5 PXF49710.1 - 0.13 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Abhydrolase_1 PF00561.20 PXF49711.1 - 5.4e-21 75.4 0.0 9.7e-20 71.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF49711.1 - 6.6e-07 30.1 0.0 7.8e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF49711.1 - 0.00027 20.3 0.0 0.0051 16.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 PXF49711.1 - 0.026 14.6 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein AAA_lid_5 PF17865.1 PXF49711.1 - 0.16 12.1 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 Midasin AAA lid domain Sec7 PF01369.20 PXF49712.1 - 7.8e-32 110.4 0.0 1.2e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Ldh_1_N PF00056.23 PXF49713.1 - 6.7e-35 120.2 0.0 1.1e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PXF49713.1 - 1.1e-19 71.0 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 PXF49713.1 - 0.0029 18.2 0.4 0.013 16.1 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 PXF49713.1 - 0.0069 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 PXF49713.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 PXF49713.1 - 0.011 15.3 0.3 0.13 11.8 0.1 2.4 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase ThiF PF00899.21 PXF49713.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 PXF49713.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 PXF49713.1 - 0.033 14.3 0.6 0.16 12.1 0.2 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.15 PXF49713.1 - 0.051 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 PXF49713.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 PXF49713.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 PXF49713.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 PXF49714.1 - 1.4e-18 67.3 0.0 2.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PXF49714.1 - 2.1e-15 57.1 0.1 4.8e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain YqjK PF13997.6 PXF49714.1 - 0.08 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 YqjK-like protein EKR PF10371.9 PXF49715.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function AIM24 PF01987.17 PXF49716.1 - 5.6e-16 58.9 0.1 6.6e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 GRDP-like PF07173.12 PXF49723.1 - 0.016 15.9 0.2 0.026 15.2 0.2 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like AT_hook PF02178.19 PXF49723.1 - 0.11 12.4 16.7 0.19 11.7 4.7 2.8 2 0 0 2 2 2 0 AT hook motif Phage_GP20 PF06810.11 PXF49724.1 - 0.0004 20.2 26.3 0.00089 19.1 0.6 4.3 3 1 1 4 4 4 3 Phage minor structural protein GP20 DUF357 PF04010.13 PXF49724.1 - 0.89 9.7 4.7 0.44 10.6 0.6 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF357) Pox_A_type_inc PF04508.12 PXF49724.1 - 0.99 9.4 5.6 31 4.6 0.2 4.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat HAGH_C PF16123.5 PXF49724.1 - 1.8 9.1 7.2 0.64 10.6 1.6 3.2 3 0 0 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus SUI1 PF01253.22 PXF49725.1 - 1.5e-16 60.7 0.4 4e-16 59.3 0.1 1.8 1 1 1 2 2 2 1 Translation initiation factor SUI1 SLC12 PF03522.15 PXF49726.1 - 0.014 14.5 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 LSM PF01423.22 PXF49727.1 - 1.3e-14 53.6 0.0 2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PXF49727.1 - 0.03 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RhlB PF12300.8 PXF49727.1 - 1.7 8.8 9.6 2.2 8.4 9.6 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Pkinase PF00069.25 PXF49728.1 - 1.9e-62 211.0 0.0 2.6e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49728.1 - 3.1e-28 98.8 0.0 4.8e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49728.1 - 1.2e-12 47.7 0.0 6.5e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PXF49728.1 - 0.065 13.1 0.7 1.2 9.0 0.3 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 PXF49729.1 - 6.9e-38 130.1 0.1 9.4e-38 129.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF49729.1 - 3.1e-21 76.0 0.0 4.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF49729.1 - 1.8e-07 31.2 0.1 3.8e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF49729.1 - 2.1e-05 24.1 0.0 7.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PXF49729.1 - 0.00037 19.7 0.2 0.00064 19.0 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 PXF49729.1 - 0.00044 20.2 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PXF49729.1 - 0.0046 16.4 0.1 0.018 14.4 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 PXF49729.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_transf_4 PF13439.6 PXF49729.1 - 0.0071 16.4 0.6 9.9 6.1 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase Family 4 ANAPC5 PF12862.7 PXF49730.1 - 1.1e-12 47.9 2.5 1.7e-12 47.2 1.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 RCC1 PF00415.18 PXF49731.1 - 1e-90 298.2 21.2 1.6e-15 57.5 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF49731.1 - 2.3e-47 157.9 38.8 7.2e-11 41.6 0.7 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat GAT PF03127.14 PXF49731.1 - 0.021 15.1 0.7 0.034 14.5 0.7 1.2 1 0 0 1 1 1 0 GAT domain DUF1459 PF07312.11 PXF49731.1 - 0.53 10.5 7.6 16 5.8 0.1 4.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1459) WD40 PF00400.32 PXF49732.1 - 2.9e-22 78.5 5.4 8.8e-07 29.5 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF49732.1 - 2.7e-08 34.0 0.2 0.13 12.6 0.0 4.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PXF49732.1 - 0.0016 17.4 0.2 0.31 9.9 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_2 PF00890.24 PXF49733.1 - 0.087 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain CAF1A PF12253.8 PXF49734.1 - 9e-21 73.8 2.9 9e-21 73.8 2.9 2.7 1 1 1 2 2 2 1 Chromatin assembly factor 1 subunit A Chloroa_b-bind PF00504.21 PXF49735.1 - 2e-38 132.5 0.0 2.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CLP_protease PF00574.23 PXF49736.1 - 8.8e-80 266.9 0.1 1e-79 266.6 0.1 1.0 1 0 0 1 1 1 1 Clp protease CactinC_cactus PF09732.9 PXF49737.1 - 2.8e-55 185.6 7.3 4.1e-55 185.0 7.3 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 PXF49737.1 - 1.1e-23 84.1 0.0 1.1e-23 84.1 0.0 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin DUF4539 PF15072.6 PXF49738.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) DUF3544 PF12064.8 PXF49738.1 - 0.36 11.1 3.4 0.47 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 ABC1 PF03109.16 PXF49739.1 - 4.5e-34 117.2 0.0 8.4e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family HTH_31 PF13560.6 PXF49739.1 - 0.46 10.9 3.6 0.56 10.6 0.3 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2040 PF09745.9 PXF49740.1 - 9.5e-21 74.1 15.6 1.1e-19 70.6 13.8 2.7 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 55 (DUF2040) DUF2570 PF10828.8 PXF49741.1 - 0.0011 18.8 0.6 0.0024 17.7 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Cu_amine_oxid PF01179.20 PXF49742.1 - 1.4e-151 505.1 0.0 1.7e-151 504.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 PXF49742.1 - 4.5e-11 43.0 0.0 1.4e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain TPR_2 PF07719.17 PXF49743.1 - 3.5e-10 39.2 27.4 0.053 13.7 0.7 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 PXF49743.1 - 8.9e-10 38.0 16.3 0.098 12.5 0.2 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 PXF49743.1 - 4.4e-09 36.5 39.4 9.2e-05 22.7 7.4 7.0 5 2 1 6 6 5 4 Tetratricopeptide repeat HEAT_2 PF13646.6 PXF49743.1 - 7.2e-09 35.9 13.3 7.4e-05 23.1 0.9 5.3 5 0 0 5 5 4 2 HEAT repeats TPR_8 PF13181.6 PXF49743.1 - 1.4e-07 31.2 6.3 4 7.9 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat HEAT PF02985.22 PXF49743.1 - 4.2e-07 29.7 8.1 0.17 12.2 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat TPR_19 PF14559.6 PXF49743.1 - 4.1e-06 27.2 30.3 0.14 12.7 1.5 7.3 5 1 3 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 PXF49743.1 - 2.7e-05 24.2 21.2 2.1 8.9 0.3 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 PXF49743.1 - 4e-05 23.3 28.4 0.36 10.8 2.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 PXF49743.1 - 0.0002 21.0 8.3 1.2 8.9 0.0 6.4 6 1 1 7 7 7 1 TPR repeat Cnd1 PF12717.7 PXF49743.1 - 0.0046 17.0 0.1 0.18 11.8 0.0 3.1 3 1 1 4 4 3 1 non-SMC mitotic condensation complex subunit 1 TPR_16 PF13432.6 PXF49743.1 - 0.017 15.7 0.7 0.23 12.2 0.1 7.0 6 2 1 8 8 5 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 PXF49743.1 - 0.061 13.9 5.7 20 5.8 0.0 4.9 5 0 0 5 5 4 0 HEAT-like repeat MMS19_C PF12460.8 PXF49743.1 - 0.062 12.4 0.0 1.8 7.6 0.0 2.3 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal TEX13 PF15186.6 PXF49743.1 - 0.44 10.2 2.2 5.8 6.6 0.1 3.5 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family TPR_7 PF13176.6 PXF49743.1 - 4.5 7.5 20.9 3.2 8.0 0.4 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TFIIA PF03153.13 PXF49743.1 - 5.2 7.0 26.3 0.21 11.5 18.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_6 PF13174.6 PXF49743.1 - 5.7 7.8 7.8 33 5.4 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 PXF49745.1 - 5.7e-48 163.6 0.0 7.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0020 PF01170.18 PXF49746.1 - 9.5e-13 48.3 0.0 2e-10 40.7 0.0 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 PXF49746.1 - 1.3e-06 28.3 0.0 0.00086 19.1 0.0 2.3 2 0 0 2 2 2 2 DNA methylase Cons_hypoth95 PF03602.15 PXF49746.1 - 0.00065 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 PXF49746.1 - 0.0028 17.0 0.0 0.015 14.6 0.0 2.0 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.10 PXF49746.1 - 0.005 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 PXF49746.1 - 0.0074 17.0 0.0 0.062 14.0 0.0 2.5 1 1 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.15 PXF49746.1 - 0.016 14.9 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_31 PF13847.6 PXF49746.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MazE_antitoxin PF04014.18 PXF49747.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin ALMT PF11744.8 PXF49748.1 - 0.11 11.3 9.7 0.13 11.1 9.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec66 PF09802.9 PXF49748.1 - 0.28 10.7 7.2 0.45 10.1 7.2 1.4 1 1 0 1 1 1 0 Preprotein translocase subunit Sec66 FUSC PF04632.12 PXF49748.1 - 0.49 8.9 13.0 0.58 8.6 13.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 PXF49748.1 - 0.7 9.4 11.6 0.92 9.0 11.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med30 PF11315.8 PXF49748.1 - 1.5 9.0 13.4 25 5.0 13.4 2.1 1 1 0 1 1 1 0 Mediator complex subunit 30 FAP206 PF12018.8 PXF49748.1 - 1.6 8.2 11.6 0.49 9.9 7.6 1.8 1 1 1 2 2 2 0 Domain of unknown function Phage_GPO PF05929.11 PXF49748.1 - 1.7 8.2 14.9 1.5e+02 1.8 14.9 2.0 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PI3K_P85_iSH2 PF16454.5 PXF49748.1 - 1.9 8.1 21.9 3.6 7.1 6.4 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Mu-like_Pro PF10123.9 PXF49748.1 - 3.6 7.1 10.6 5.9 6.3 10.6 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein PIN_12 PF16289.5 PXF49748.1 - 3.7 8.0 9.3 0.92 10.0 5.0 1.9 1 1 1 2 2 2 0 PIN domain Med10 PF09748.9 PXF49748.1 - 4.1 7.4 10.0 3 7.8 2.6 2.5 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex FAM76 PF16046.5 PXF49748.1 - 10 5.4 10.3 17 4.7 10.3 1.3 1 0 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 PXF49749.1 - 0.021 14.6 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRA1 PF07304.11 PXF49749.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) zf-C2H2 PF00096.26 PXF49751.1 - 7.6e-06 26.1 9.2 0.0074 16.7 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PXF49751.1 - 0.012 16.0 0.3 0.012 16.0 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Sigma54_CBD PF04963.13 PXF49751.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain zf-C2H2_aberr PF17017.5 PXF49751.1 - 0.21 11.7 0.3 1.5 8.9 0.1 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 PXF49751.1 - 0.28 12.1 8.8 6.7 7.8 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Sigma70_r4 PF04545.16 PXF49753.1 - 0.069 12.7 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase PF00069.25 PXF49754.1 - 1.7e-38 132.5 0.0 2.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49754.1 - 1.5e-16 60.5 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49754.1 - 6e-06 25.8 0.0 1.5e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PXF49754.1 - 0.0042 16.5 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 PXF49755.1 - 2.1e-20 73.0 29.1 2.1e-20 73.0 29.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3796 PF12676.7 PXF49755.1 - 0.44 11.0 5.9 0.16 12.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF1202 PF06717.11 PXF49756.1 - 0.029 13.8 0.2 0.033 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) CDC73_N PF16050.5 PXF49756.1 - 0.05 12.9 1.0 0.099 11.9 0.6 1.6 1 1 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal mRNA_triPase PF02940.15 PXF49756.1 - 0.052 13.3 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain RCC1 PF00415.18 PXF49757.1 - 1.5e-67 224.0 11.7 2.4e-12 47.3 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PXF49757.1 - 2.7e-25 87.6 31.2 2.3e-08 33.6 0.2 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat FTP PF07504.13 PXF49757.1 - 0.13 12.2 0.3 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif UPF0029 PF01205.19 PXF49758.1 - 2.5e-33 114.5 0.2 1.2e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 PXF49758.1 - 1.2e-08 35.2 0.1 2.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 RWD domain PEP-utilisers_N PF05524.13 PXF49758.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Syntaxin-6_N PF09177.11 PXF49759.1 - 9.2e-11 42.2 2.5 2.8e-09 37.4 1.0 2.9 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 PXF49759.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 SNARE domain KxDL PF10241.9 PXF49759.1 - 0.026 14.8 2.6 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein PRAI PF00697.22 PXF49759.1 - 0.035 13.9 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2884 PF11101.8 PXF49759.1 - 0.84 9.1 7.5 11 5.4 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) SlyX PF04102.12 PXF49759.1 - 3.9 8.1 7.6 75 4.1 1.5 3.6 3 1 0 3 3 3 0 SlyX Cupin_8 PF13621.6 PXF49760.1 - 4.6e-08 33.1 0.1 2.7e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PXF49760.1 - 0.00029 21.3 0.0 0.0041 17.5 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Ank_3 PF13606.6 PXF49760.1 - 0.00052 20.3 0.0 0.0038 17.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PXF49760.1 - 0.00062 20.3 0.0 0.0095 16.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PXF49760.1 - 0.0019 18.7 0.1 0.016 15.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PXF49760.1 - 0.0088 16.5 0.1 0.038 14.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Cupin_4 PF08007.12 PXF49760.1 - 0.016 14.6 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Ank_5 PF13857.6 PXF49760.1 - 0.02 15.2 0.0 0.072 13.4 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Fes1 PF08609.10 PXF49761.1 - 0.33 11.9 0.1 0.33 11.9 0.1 2.4 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 ALMT PF11744.8 PXF49761.1 - 2.3 6.9 6.5 3.2 6.5 6.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Phosphodiest PF01663.22 PXF49762.1 - 2.6e-43 149.0 0.7 3e-43 148.8 0.7 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Baculo_LEF-11 PF06385.12 PXF49763.1 - 0.089 13.3 0.1 0.23 12.0 0.0 1.7 1 1 0 1 1 1 0 Baculovirus LEF-11 protein FAD_binding_3 PF01494.19 PXF49764.1 - 1.9e-29 103.1 0.2 3.5e-29 102.1 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain UbiA PF01040.18 PXF49764.1 - 6.5e-16 58.4 16.8 1.1e-15 57.7 16.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DAO PF01266.24 PXF49764.1 - 2.5e-07 30.6 2.2 6.5e-07 29.3 1.4 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PXF49764.1 - 1.7e-06 28.1 0.5 6.9e-06 26.2 0.5 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PXF49764.1 - 3.4e-06 26.4 1.3 5.7e-06 25.7 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 PXF49764.1 - 6e-05 22.4 0.2 0.00012 21.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PXF49764.1 - 0.00013 21.3 0.1 0.00023 20.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PXF49764.1 - 0.00016 20.5 0.3 0.00039 19.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 PXF49764.1 - 0.0002 20.7 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF49764.1 - 0.0005 19.3 0.8 0.0025 17.0 0.4 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 PXF49764.1 - 0.0011 18.4 0.9 0.0016 17.9 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PXF49764.1 - 0.0029 16.5 0.1 0.0063 15.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 PXF49764.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF49764.1 - 0.017 15.7 2.4 0.024 15.2 0.1 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PXF49764.1 - 0.045 13.6 0.8 0.081 12.8 0.2 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 PXF49764.1 - 0.059 12.6 0.3 0.059 12.6 0.3 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 PXF49764.1 - 0.065 12.3 0.2 0.065 12.3 0.2 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 PXF49764.1 - 0.069 13.6 0.0 0.19 12.2 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding MCRA PF06100.11 PXF49764.1 - 0.12 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 MCRA family CCT PF06203.14 PXF49765.1 - 1.2e-16 60.5 12.1 1.9e-16 59.8 12.1 1.4 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 PXF49765.1 - 2.3e-06 27.7 2.6 3.9e-06 26.9 2.6 1.3 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 PXF49765.1 - 0.01 16.1 2.0 0.021 15.1 2.0 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain RPE65 PF03055.15 PXF49767.1 - 4.4e-77 260.3 0.1 5.1e-77 260.0 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amidinotransf PF02274.17 PXF49768.1 - 0.0023 17.1 0.0 0.0079 15.3 0.0 1.8 2 0 0 2 2 2 1 Amidinotransferase Raptor_N PF14538.6 PXF49769.1 - 1.6e-56 190.4 0.0 3e-56 189.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 PXF49769.1 - 1.7e-11 44.4 0.3 0.0047 17.7 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT_2 PF13646.6 PXF49769.1 - 0.00016 22.0 0.1 0.013 15.9 0.0 2.8 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PXF49769.1 - 0.00025 21.1 0.1 1.5 9.3 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat ANAPC4_WD40 PF12894.7 PXF49769.1 - 0.004 17.4 0.0 15 5.9 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C14 PF00656.22 PXF49769.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Caspase domain PALB2_WD40 PF16756.5 PXF49769.1 - 0.21 10.5 0.1 0.39 9.6 0.1 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Abhydrolase_6 PF12697.7 PXF49770.1 - 1e-19 72.0 2.5 1e-19 72.0 2.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PXF49770.1 - 1.2e-18 67.3 0.0 1.5e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF49770.1 - 8.5e-17 61.6 0.4 2.2e-16 60.3 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 PXF49770.1 - 0.00028 20.6 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 PXF49770.1 - 0.00029 20.8 0.2 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.14 PXF49770.1 - 0.0016 17.2 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 PXF49770.1 - 0.0038 16.2 0.1 0.0078 15.1 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 PXF49770.1 - 0.016 14.7 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3530 PF12048.8 PXF49770.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydro_lipase PF04083.16 PXF49770.1 - 0.03 13.9 0.2 0.067 12.8 0.2 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Thioesterase PF00975.20 PXF49770.1 - 0.035 14.2 0.3 0.072 13.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase PF07224.11 PXF49770.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Methyltransf_21 PF05050.12 PXF49771.1 - 9.6e-08 32.2 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain RRM_1 PF00076.22 PXF49772.1 - 6.1e-17 61.2 0.0 3.5e-08 33.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PXF49772.1 - 0.0009 19.0 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif SPOC PF07744.13 PXF49772.1 - 0.005 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 SPOC domain FAD_binding_3 PF01494.19 PXF49773.1 - 5.9e-18 65.2 0.1 8.8e-08 31.8 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 PXF49773.1 - 6.4e-08 32.1 0.2 0.023 13.8 0.0 3.3 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 PXF49773.1 - 0.0007 19.6 0.0 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 PXF49773.1 - 0.0038 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PXF49773.1 - 0.007 15.3 0.0 1.6 7.5 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 PXF49773.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 PXF49773.1 - 0.15 12.3 0.8 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 PXF49774.1 - 3.4e-150 500.6 0.7 4.1e-150 500.3 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PALP PF00291.25 PXF49775.1 - 3e-73 246.8 2.3 3.8e-73 246.5 2.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GARS_N PF02844.15 PXF49775.1 - 0.059 14.1 0.8 0.46 11.3 0.2 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Aminotran_1_2 PF00155.21 PXF49777.1 - 1.8e-60 205.1 0.0 2.7e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PXF49777.1 - 2.7e-05 23.3 0.0 0.00057 18.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PXF49777.1 - 0.0011 17.6 0.0 0.01 14.4 0.0 2.2 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PXF49777.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 PXF49777.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Pkinase PF00069.25 PXF49778.1 - 1.2e-71 241.2 0.0 1.8e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49778.1 - 4.2e-50 170.4 0.0 7e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 PXF49778.1 - 2.3e-14 52.8 4.7 0.0013 18.7 0.0 7.0 6 1 0 6 6 6 3 Armadillo/beta-catenin-like repeat Kdo PF06293.14 PXF49778.1 - 3e-05 23.5 0.0 7.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PXF49778.1 - 0.00021 20.7 0.0 0.012 14.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PXF49778.1 - 0.0013 17.8 0.0 0.0013 17.8 0.0 1.7 2 0 0 2 2 1 1 Haspin like kinase domain Atx10homo_assoc PF09759.9 PXF49778.1 - 0.0019 18.2 0.0 0.82 9.7 0.0 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Pkinase_fungal PF17667.1 PXF49778.1 - 0.073 11.8 3.3 0.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 PXF49778.1 - 0.1 12.5 0.0 0.1 12.5 0.0 3.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family TFIIA PF03153.13 PXF49778.1 - 0.53 10.2 16.3 0.97 9.4 16.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HEAT_EZ PF13513.6 PXF49778.1 - 1.3 9.6 8.4 0.89 10.1 0.2 4.4 4 0 0 4 4 4 0 HEAT-like repeat EXOSC1 PF10447.9 PXF49779.1 - 0.0049 17.5 0.4 2.4 8.8 0.1 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 Kinesin PF00225.23 PXF49780.1 - 1.8e-105 352.6 0.0 3.3e-105 351.7 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PXF49780.1 - 6.9e-25 87.7 0.0 1.4e-23 83.5 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding SKA2 PF16740.5 PXF49780.1 - 0.0062 16.3 2.1 0.068 13.0 1.3 2.4 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 GOLGA2L5 PF15070.6 PXF49780.1 - 0.0066 15.2 7.1 0.011 14.4 7.1 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Tup_N PF08581.10 PXF49780.1 - 0.011 16.0 4.7 0.5 10.7 1.9 2.6 2 0 0 2 2 2 0 Tup N-terminal YabA PF06156.13 PXF49780.1 - 0.018 15.6 7.3 1.3 9.7 3.6 3.7 3 1 0 3 3 3 0 Initiation control protein YabA TSC22 PF01166.18 PXF49780.1 - 0.026 14.8 5.9 0.18 12.2 1.9 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 PXF49780.1 - 0.031 15.2 10.8 2 9.4 0.0 3.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SOGA PF11365.8 PXF49780.1 - 0.039 15.1 2.4 0.039 15.1 2.4 2.8 1 1 2 3 3 2 0 Protein SOGA Troponin PF00992.20 PXF49780.1 - 0.073 13.4 8.2 0.047 14.0 4.3 2.2 2 0 0 2 2 2 0 Troponin GAS PF13851.6 PXF49780.1 - 0.078 12.3 14.4 0.22 10.8 8.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 PXF49780.1 - 0.11 12.4 5.9 0.22 11.4 3.7 2.1 2 0 0 2 2 2 0 Sec34-like family PI3K_P85_iSH2 PF16454.5 PXF49780.1 - 0.11 12.1 4.8 0.52 9.9 1.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BRE1 PF08647.11 PXF49780.1 - 0.2 11.7 7.8 0.6 10.2 4.5 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CCDC-167 PF15188.6 PXF49780.1 - 0.33 11.3 3.9 10 6.5 0.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FliD_N PF02465.18 PXF49780.1 - 0.46 11.2 7.3 0.25 12.1 3.3 2.7 1 1 2 3 3 2 0 Flagellar hook-associated protein 2 N-terminus APG6_N PF17675.1 PXF49780.1 - 0.57 10.7 17.8 1.7 9.1 10.5 2.6 1 1 0 2 2 2 0 Apg6 coiled-coil region VPS38 PF17649.1 PXF49780.1 - 0.68 8.7 2.8 1.3 7.8 2.8 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DegS PF05384.11 PXF49780.1 - 0.74 9.3 11.8 0.086 12.3 7.1 1.8 2 0 0 2 2 2 0 Sensor protein DegS DUF724 PF05266.14 PXF49780.1 - 0.95 9.3 11.3 2.1 8.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 PXF49780.1 - 1 9.6 16.2 1.3 9.2 8.1 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 PXF49780.1 - 1.1 8.1 15.1 1.4 7.7 7.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein EzrA PF06160.12 PXF49780.1 - 1.4 7.0 12.9 4.1 5.5 10.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA OmpH PF03938.14 PXF49780.1 - 1.4 9.2 5.8 2.5 8.4 1.8 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EMP24_GP25L PF01105.24 PXF49780.1 - 1.5 8.7 9.1 0.54 10.2 1.9 2.8 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.6 PXF49780.1 - 2.9 7.2 12.5 1.1 8.5 8.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 PXF49780.1 - 2.9 8.3 8.1 1.6 9.2 0.9 3.3 2 2 1 3 3 3 0 Csm1 N-terminal domain DUF2408 PF10303.9 PXF49780.1 - 2.9 8.4 7.2 10 6.7 6.7 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF2408) JIP_LZII PF16471.5 PXF49780.1 - 3 8.1 6.9 19 5.5 0.1 2.9 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II GrpE PF01025.19 PXF49780.1 - 3.4 7.3 12.0 0.31 10.7 6.0 2.1 2 0 0 2 2 2 0 GrpE TPR_MLP1_2 PF07926.12 PXF49780.1 - 4.9 7.2 19.4 1.6 8.8 0.7 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 PXF49780.1 - 6.9 6.4 13.3 19 4.9 8.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ZapB PF06005.12 PXF49780.1 - 8.5 6.9 11.0 28 5.2 6.8 2.9 2 1 0 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 PXF49780.1 - 8.7 6.7 17.0 1.1e+02 3.1 17.0 2.3 1 1 0 1 1 1 0 Fez1 Uso1_p115_C PF04871.13 PXF49780.1 - 9.9 6.6 20.7 1.5 9.2 3.8 3.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Kinesin PF00225.23 PXF49781.1 - 1.8e-105 352.5 0.2 1.8e-105 352.5 0.2 2.6 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PXF49781.1 - 3.3e-26 92.0 0.0 3.3e-26 92.0 0.0 3.1 3 0 0 3 3 3 1 Microtubule binding Seryl_tRNA_N PF02403.22 PXF49781.1 - 0.018 15.2 0.6 0.018 15.2 0.6 9.7 5 2 2 9 9 9 0 Seryl-tRNA synthetase N-terminal domain Vip3A_N PF12495.8 PXF49781.1 - 0.15 11.9 1.2 0.82 9.5 0.6 2.6 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal Shugoshin_N PF07558.11 PXF49781.1 - 0.19 11.6 9.4 0.8 9.6 0.0 5.2 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Proteasome PF00227.26 PXF49782.1 - 1.2e-43 148.8 0.0 1.3e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ABC_sub_bind PF04392.12 PXF49783.1 - 0.022 14.0 0.1 0.044 13.0 0.0 1.4 2 0 0 2 2 2 0 ABC transporter substrate binding protein Aminotran_1_2 PF00155.21 PXF49784.1 - 1.6e-57 195.3 0.0 2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 PXF49784.1 - 7.2e-05 21.6 0.1 0.00011 21.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_MocR PF12897.7 PXF49784.1 - 0.00023 20.1 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 PXF49784.1 - 0.0023 16.5 0.1 0.0033 16.0 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 PXF49784.1 - 0.018 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Alliinase_C PF04864.13 PXF49784.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Allinase DegT_DnrJ_EryC1 PF01041.17 PXF49784.1 - 0.028 13.7 1.3 0.042 13.2 1.3 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PXF49784.1 - 0.048 12.9 0.0 0.17 11.2 0.0 1.8 3 0 0 3 3 3 0 Beta-eliminating lyase IKI3 PF04762.12 PXF49785.1 - 1.5e-125 420.3 0.0 2.4e-81 274.1 0.0 3.1 1 1 2 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 PXF49785.1 - 0.13 12.6 0.0 20 5.6 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CCDC168_N PF15804.5 PXF49785.1 - 0.21 11.4 0.8 0.38 10.6 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 168 VWA_2 PF13519.6 PXF49786.1 - 1.4e-18 67.5 0.0 4.6e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 PXF49786.1 - 4.8e-07 29.8 0.0 7.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 PXF49786.1 - 0.0024 17.7 16.1 0.0052 16.6 2.1 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif ABM PF03992.16 PXF49787.1 - 2.4e-14 53.2 0.0 2.6e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 PXF49787.1 - 0.0066 16.8 0.0 0.007 16.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF131 PF01998.17 PXF49788.1 - 0.081 12.6 0.5 0.092 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF131 Ost4 PF10215.9 PXF49788.1 - 0.43 10.4 7.7 0.64 9.9 7.7 1.4 1 1 0 1 1 1 0 Oligosaccaryltransferase FAD_binding_3 PF01494.19 PXF49789.1 - 9.2e-12 44.9 0.8 3.2e-06 26.7 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PXF49789.1 - 3.3e-06 26.5 0.0 5.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF49789.1 - 6.5e-06 25.5 0.5 9.4e-06 24.9 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PXF49789.1 - 1.1e-05 24.7 0.1 0.056 12.5 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 PXF49789.1 - 1.8e-05 24.8 0.1 5.5e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF49789.1 - 5.4e-05 22.9 0.6 0.0047 16.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PXF49789.1 - 0.00025 20.5 0.8 0.00053 19.5 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PXF49789.1 - 0.00038 19.3 0.3 0.00057 18.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 PXF49789.1 - 0.0014 18.6 0.4 2.1 8.3 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 PXF49789.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 PXF49789.1 - 0.0017 17.6 0.4 0.0034 16.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 PXF49789.1 - 0.015 15.2 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PXF49789.1 - 0.018 15.6 0.3 0.067 13.8 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 PXF49789.1 - 0.019 14.3 0.1 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.14 PXF49789.1 - 0.039 12.8 0.4 0.36 9.6 0.3 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 PXF49789.1 - 0.048 14.1 0.1 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 PXF49789.1 - 0.087 12.1 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PXF49789.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cyclin PF08613.11 PXF49790.1 - 1e-19 71.5 0.9 1.8e-19 70.7 0.9 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PXF49790.1 - 3.1e-05 23.7 0.1 5.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RAP1 PF07218.11 PXF49792.1 - 1.5 7.0 16.0 2 6.6 16.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3446 PF11928.8 PXF49792.1 - 3.9 7.8 28.5 2.8 8.3 17.3 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Presenilin PF01080.17 PXF49792.1 - 4.6 5.9 4.3 4.8 5.9 4.3 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 PXF49792.1 - 6.7 5.4 13.0 8 5.2 13.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HGTP_anticodon PF03129.20 PXF49793.1 - 7e-21 74.2 0.2 2.6e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PXF49793.1 - 2.4e-09 37.4 0.1 7.9e-09 35.7 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) PMEI PF04043.15 PXF49793.1 - 0.17 12.2 3.9 0.38 11.1 3.9 1.5 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor PP2C PF00481.21 PXF49794.1 - 5.2e-40 137.7 0.0 1.7e-37 129.5 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PXF49794.1 - 2.9e-06 27.1 0.0 7.7e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C TFIIA PF03153.13 PXF49794.1 - 0.16 12.0 17.6 0.29 11.1 17.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PXF49794.1 - 3.4 7.2 22.9 5.1 6.6 22.9 1.2 1 0 0 1 1 1 0 Spt20 family YdfA_immunity PF12127.8 PXF49795.1 - 0.081 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 SigmaW regulon antibacterial zf-RING_2 PF13639.6 PXF49796.1 - 7.3e-10 39.0 8.0 1.7e-09 37.8 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PXF49796.1 - 5.4e-08 33.0 7.9 5.4e-08 33.0 7.9 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PXF49796.1 - 2.2e-07 30.6 4.4 3.8e-07 29.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PXF49796.1 - 4.8e-07 29.5 7.6 1e-06 28.5 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PXF49796.1 - 3.5e-06 26.8 7.0 6.3e-06 26.0 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF49796.1 - 3.6e-06 26.9 3.1 7e-06 26.0 3.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PXF49796.1 - 3.6e-06 26.7 4.5 6.8e-06 25.9 4.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PXF49796.1 - 0.00025 20.9 5.5 0.00048 20.0 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PXF49796.1 - 0.0017 18.5 5.4 0.0035 17.5 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 PXF49796.1 - 0.0017 18.0 3.9 0.0038 16.9 3.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 PXF49796.1 - 0.0086 15.7 3.7 0.016 14.8 3.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 PXF49796.1 - 0.011 15.8 3.5 0.011 15.8 3.5 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger 4HB_MCP_1 PF12729.7 PXF49796.1 - 0.021 14.4 3.1 0.053 13.1 3.1 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SPAM PF02090.15 PXF49796.1 - 0.13 12.1 4.1 0.042 13.7 0.6 1.9 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein FANCL_C PF11793.8 PXF49796.1 - 0.21 11.8 3.5 0.78 10.0 3.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 PXF49796.1 - 8.3 6.6 7.5 21 5.3 7.5 1.7 1 0 0 1 1 1 0 RING-variant domain RRXRR PF14239.6 PXF49797.1 - 0.013 15.4 3.8 0.023 14.6 3.8 1.4 1 0 0 1 1 1 0 RRXRR protein GAPT PF11770.8 PXF49797.1 - 0.042 13.7 0.7 0.077 12.9 0.7 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Clathrin_H_link PF13838.6 PXF49799.1 - 1.1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 PXF49799.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Clathrin, heavy-chain linker REC114-like PF15165.6 PXF49801.1 - 0.0009 19.1 0.2 0.001 18.9 0.2 1.0 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like Hint PF01079.20 PXF49802.1 - 1.8e-20 73.4 0.2 4.4e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Hint module Intein_splicing PF14890.6 PXF49802.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Intein splicing domain Hint_2 PF13403.6 PXF49802.1 - 0.041 14.2 0.2 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Hint domain Sel1 PF08238.12 PXF49803.1 - 9e-19 67.5 20.4 0.00088 19.9 0.0 9.8 11 0 0 11 11 11 4 Sel1 repeat TPR_11 PF13414.6 PXF49803.1 - 0.00081 19.0 11.1 0.18 11.5 1.5 4.7 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 PXF49803.1 - 0.0076 16.4 2.2 1.4 9.3 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TIG PF01833.24 PXF49803.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 IPT/TIG domain TPR_16 PF13432.6 PXF49803.1 - 0.19 12.4 47.8 0.16 12.6 3.4 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49803.1 - 0.52 10.5 0.1 0.52 10.5 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF49803.1 - 1.8 8.8 11.7 0.3 11.3 0.2 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Amidase PF01425.21 PXF49804.1 - 1.7e-80 271.2 0.1 2.1e-80 270.9 0.1 1.0 1 0 0 1 1 1 1 Amidase DUF150 PF02576.17 PXF49805.1 - 1.6e-07 31.6 0.1 2.4e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 PXF49805.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 RimP C-terminal SH3 domain DEAD PF00270.29 PXF49807.1 - 2.9e-45 154.2 0.1 4.8e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF49807.1 - 5.2e-29 100.8 0.0 3e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF49807.1 - 0.00087 19.3 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF49807.1 - 0.022 15.1 1.6 0.17 12.2 1.0 2.7 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.19 PXF49807.1 - 0.19 11.2 0.1 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NT-C2 PF10358.9 PXF49808.1 - 2.5e-11 43.5 0.3 4.2e-11 42.7 0.3 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4763 PF15960.5 PXF49808.1 - 0.04 13.2 4.2 0.068 12.5 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) HALZ PF02183.18 PXF49808.1 - 0.14 12.4 3.7 0.32 11.2 0.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glu-tRNAGln PF02686.15 PXF49809.1 - 7.4e-15 55.0 0.7 1e-14 54.6 0.7 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF1456 PF07308.13 PXF49809.1 - 0.023 15.0 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) Pkinase PF00069.25 PXF49810.1 - 7.8e-73 245.1 0.0 1.1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49810.1 - 3.9e-35 121.4 0.0 6.6e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF49810.1 - 2.2e-06 27.2 0.0 4.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PXF49810.1 - 0.0019 17.3 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PXF49810.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PXF49810.1 - 0.023 14.0 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fcf1 PF04900.12 PXF49811.1 - 2.6e-17 63.0 0.1 1.3e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 Fcf1 APP_amyloid PF10515.9 PXF49811.1 - 0.14 12.7 1.9 15 6.2 0.0 3.7 2 1 1 3 3 3 0 Beta-amyloid precursor protein C-terminus RNA_pol_L_2 PF13656.6 PXF49812.1 - 9.3e-29 99.0 0.1 7.9e-28 96.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PXF49812.1 - 4e-13 48.6 0.0 1e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TIP49 PF06068.13 PXF49813.1 - 1.2e-167 557.6 0.2 3.5e-167 556.0 0.2 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 PXF49813.1 - 1.1e-17 63.9 0.2 4.3e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 PXF49813.1 - 2.5e-09 37.6 0.3 6.2e-06 26.7 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PXF49813.1 - 2e-08 34.1 0.7 2.5e-05 24.1 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PXF49813.1 - 2.1e-05 24.8 0.1 0.015 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 PXF49813.1 - 0.002 18.1 0.1 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PXF49813.1 - 0.0021 18.4 0.2 1.9 8.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PXF49813.1 - 0.0026 18.2 0.1 0.029 14.8 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 PXF49813.1 - 0.0033 17.1 0.3 2 8.1 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 PXF49813.1 - 0.0083 16.1 0.2 2.7 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 PXF49813.1 - 0.0093 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TFIID-31kDa PF02291.15 PXF49813.1 - 0.02 14.9 0.1 0.46 10.6 0.3 2.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Mg_chelatase PF01078.21 PXF49813.1 - 0.062 12.7 0.7 2.6 7.4 0.3 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 PXF49813.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PXF49813.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 PXF49813.1 - 0.14 11.4 0.5 0.33 10.2 0.5 1.5 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 PXF49813.1 - 0.16 12.0 0.1 3.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MFS_1_like PF12832.7 PXF49815.1 - 6.4e-52 176.7 17.0 9.5e-52 176.1 17.0 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PXF49815.1 - 3.8e-13 49.1 33.8 1.9e-08 33.6 8.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 PXF49815.1 - 0.059 13.4 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 CoA-binding domain TssO PF17561.2 PXF49815.1 - 2.3 8.3 4.7 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssO CPP1-like PF11833.8 PXF49815.1 - 3.7 7.2 8.6 1.2 8.8 1.8 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pox_A14 PF05767.12 PXF49815.1 - 4.8 7.4 8.2 0.37 11.0 0.2 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 S4 PF01479.25 PXF49816.1 - 8e-11 41.5 0.8 8e-11 41.5 0.8 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 PXF49816.1 - 4.6e-06 27.5 0.5 9.1e-06 26.5 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain RNA_pol_Rbc25 PF08292.12 PXF49817.1 - 1.1e-18 67.7 2.5 6.5e-18 65.2 2.5 2.0 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PXF49817.1 - 1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Glutaredoxin PF00462.24 PXF49818.1 - 8.1e-17 61.2 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 PXF49818.1 - 0.0024 18.3 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 PXF49818.1 - 0.0028 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.20 PXF49818.1 - 0.023 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 PXF49818.1 - 0.044 14.2 0.3 0.08 13.4 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 PXF49818.1 - 0.21 11.7 0.1 3.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin DSBA PF01323.20 PXF49818.1 - 0.53 10.0 2.1 1.3 8.7 0.5 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Peptidase_M24 PF00557.24 PXF49819.1 - 2.2e-41 141.8 0.0 3.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SART-1 PF03343.13 PXF49819.1 - 0.0018 16.9 2.7 0.0024 16.5 2.7 1.1 1 0 0 1 1 1 1 SART-1 family NST1 PF13945.6 PXF49819.1 - 0.019 15.1 3.4 0.029 14.5 3.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator ApbE PF02424.15 PXF49819.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 ApbE family Yippee-Mis18 PF03226.14 PXF49820.1 - 9.9e-17 61.1 4.0 1.7e-16 60.3 4.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF848 PF05852.11 PXF49820.1 - 0.016 15.3 0.7 0.046 13.8 0.4 2.0 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) FAM184 PF15665.5 PXF49820.1 - 0.048 13.4 0.5 0.082 12.7 0.5 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TSNAXIP1_N PF15739.5 PXF49820.1 - 0.061 13.7 0.6 21 5.5 0.3 3.1 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus RIG-I_C-RD PF11648.8 PXF49820.1 - 0.12 12.6 1.3 0.23 11.7 1.3 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I BLOC1_2 PF10046.9 PXF49820.1 - 0.18 12.1 0.3 11 6.4 0.2 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.23 PXF49821.1 - 4.3e-09 37.1 2.5 8.4e-09 36.1 2.5 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Imm6 PF14434.6 PXF49821.1 - 0.06 13.3 1.2 0.13 12.2 1.2 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 FliG_N PF14842.6 PXF49821.1 - 0.36 11.4 3.0 3.5 8.2 0.4 2.6 2 0 0 2 2 2 0 FliG N-terminal domain Methyltransf_11 PF08241.12 PXF49822.1 - 2e-10 41.1 0.0 4.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49822.1 - 6.6e-07 30.0 0.1 3.3e-06 27.7 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF49822.1 - 8.4e-06 25.3 0.0 1.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PXF49822.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49822.1 - 0.00063 19.6 0.0 0.00087 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF49822.1 - 0.0032 18.2 0.0 0.0056 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PXF49822.1 - 0.0033 17.1 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 PXF49822.1 - 0.055 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 PXF49822.1 - 0.16 10.5 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cation_efflux PF01545.21 PXF49823.1 - 1.3e-24 87.0 12.6 1.3e-24 87.0 12.6 2.3 2 0 0 2 2 2 1 Cation efflux family Ykof PF07615.11 PXF49823.1 - 0.0065 16.9 0.0 0.074 13.5 0.0 2.4 2 0 0 2 2 2 1 YKOF-related Family DUF4199 PF13858.6 PXF49823.1 - 0.068 13.6 6.7 0.12 12.7 1.9 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SUa-2TM PF18179.1 PXF49824.1 - 0.11 11.8 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Tetraspanin PF00335.20 PXF49824.1 - 0.11 12.2 12.3 0.74 9.5 12.3 2.1 1 1 0 1 1 1 0 Tetraspanin family UCH PF00443.29 PXF49825.1 - 5.9e-20 71.8 0.0 7.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PXF49825.1 - 3.3e-09 36.9 3.8 5.9e-09 36.1 2.6 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Hydrolase_4 PF12146.8 PXF49826.1 - 1.3e-16 60.7 0.0 1.9e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PXF49826.1 - 2.9e-12 47.7 0.0 3.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF49826.1 - 1.6e-10 41.1 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 PXF49826.1 - 0.0015 17.5 0.0 0.0044 16.0 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 PXF49826.1 - 0.071 12.6 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 PXF49826.1 - 0.17 11.7 0.0 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SRP9-21 PF05486.12 PXF49827.1 - 2.3e-08 34.3 1.0 1.2e-06 28.8 1.0 2.2 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) RRP36 PF06102.12 PXF49828.1 - 2.5e-38 131.6 18.9 3.9e-38 131.0 18.9 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 LYTB PF02401.18 PXF49829.1 - 2.7e-77 259.6 0.0 3.3e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 LytB protein Potyvirid-P3 PF13608.6 PXF49829.1 - 0.092 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Recombinase PF07508.13 PXF49829.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Recombinase LMWPc PF01451.21 PXF49830.1 - 3.6e-07 30.7 0.0 5.5e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase bZIP_1 PF00170.21 PXF49831.1 - 1.1e-06 28.6 8.1 1.1e-06 28.6 8.1 1.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PXF49831.1 - 2.9e-05 24.0 6.2 2.9e-05 24.0 6.2 2.3 1 1 1 2 2 2 1 Basic region leucine zipper Mobilization_B PF17511.2 PXF49831.1 - 0.0048 17.3 1.2 0.0061 16.9 1.2 1.2 1 0 0 1 1 1 1 Mobilization protein B bZIP_Maf PF03131.17 PXF49831.1 - 0.011 16.3 8.6 0.011 16.3 8.6 1.5 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF4081 PF13312.6 PXF49831.1 - 0.06 13.6 2.4 0.08 13.1 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) LUC7 PF03194.15 PXF49831.1 - 0.1 12.2 4.4 0.11 12.2 4.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus YabA PF06156.13 PXF49831.1 - 0.74 10.5 5.7 0.45 11.2 0.9 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Ribosomal_L37 PF08561.10 PXF49831.1 - 1.4 9.4 5.0 1.6 9.2 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Sds3 PF08598.11 PXF49832.1 - 0.049 13.6 6.0 0.078 13.0 6.0 1.2 1 0 0 1 1 1 0 Sds3-like FAM92 PF06730.11 PXF49832.1 - 0.087 12.2 1.4 0.13 11.7 1.4 1.2 1 0 0 1 1 1 0 FAM92 protein DnaJ PF00226.31 PXF49833.1 - 4.4e-15 55.6 0.0 8.5e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Prefoldin_2 PF01920.20 PXF49834.1 - 0.00022 21.2 0.8 0.0003 20.7 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Snapin_Pallidin PF14712.6 PXF49834.1 - 0.00096 19.5 4.3 0.0021 18.5 4.3 1.6 1 1 0 1 1 1 1 Snapin/Pallidin CENP-F_leu_zip PF10473.9 PXF49834.1 - 0.0018 18.3 5.2 0.0023 17.9 5.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IL11 PF07400.11 PXF49834.1 - 0.0084 15.8 2.2 0.61 9.7 1.4 2.1 1 1 1 2 2 2 1 Interleukin 11 SesA PF17107.5 PXF49834.1 - 0.026 14.7 0.6 0.036 14.3 0.6 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Dict-STAT-coil PF09267.10 PXF49834.1 - 0.032 14.6 1.7 0.044 14.2 1.7 1.2 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Lebercilin PF15619.6 PXF49834.1 - 0.044 13.4 6.3 0.055 13.1 6.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Spc24 PF08286.11 PXF49834.1 - 0.075 13.3 3.2 0.14 12.4 3.2 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CheZ PF04344.13 PXF49834.1 - 0.078 12.9 1.7 0.096 12.6 1.7 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ YlqD PF11068.8 PXF49834.1 - 0.1 12.9 1.6 0.13 12.7 1.6 1.3 1 0 0 1 1 1 0 YlqD protein GCN5L1 PF06320.13 PXF49834.1 - 0.11 12.7 1.0 0.19 11.9 1.0 1.5 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) IFP_35_N PF07334.13 PXF49834.1 - 0.11 12.6 1.9 0.2 11.7 1.9 1.6 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TMPIT PF07851.13 PXF49834.1 - 0.14 11.4 0.8 0.16 11.2 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 PXF49834.1 - 0.18 10.4 0.9 0.2 10.2 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF948 PF06103.11 PXF49834.1 - 0.2 11.9 0.7 0.65 10.3 0.7 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 PXF49834.1 - 0.33 11.5 6.8 0.43 11.1 6.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 PXF49834.1 - 0.36 9.3 4.3 0.4 9.2 4.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family T3SS_needle_E PF08988.10 PXF49834.1 - 0.37 11.0 9.2 3.2 7.9 0.8 3.1 2 2 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Exonuc_VII_L PF02601.15 PXF49834.1 - 0.58 9.7 3.6 0.65 9.5 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit KfrA_N PF11740.8 PXF49834.1 - 3 8.5 8.6 1.3 9.7 6.4 1.6 2 0 0 2 2 1 0 Plasmid replication region DNA-binding N-term DTW PF03942.15 PXF49835.1 - 2e-29 102.7 1.5 2.7e-29 102.3 1.5 1.2 1 0 0 1 1 1 1 DTW domain RNA_pol_Rpb1_3 PF04983.18 PXF49838.1 - 5.2e-44 149.9 0.0 8.5e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 PXF49838.1 - 7.8e-41 140.1 0.8 8.1e-40 136.7 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 PXF49838.1 - 1.6e-32 111.7 0.1 3.9e-32 110.4 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 4 MCPVI PF02993.14 PXF49838.1 - 0.15 11.9 0.5 0.22 11.3 0.5 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Adap_comp_sub PF00928.21 PXF49839.1 - 2.8e-13 49.8 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Tic110 PF16940.5 PXF49840.1 - 8.7e-05 21.2 2.4 0.11 11.0 0.2 3.0 1 1 1 3 3 3 3 Chloroplast envelope transporter PALP PF00291.25 PXF49841.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ABC_membrane PF00664.23 PXF49842.1 - 7.8e-56 189.7 2.6 1.1e-55 189.3 2.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PXF49842.1 - 1.5e-31 109.7 0.0 2.8e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PXF49842.1 - 2.7e-05 23.7 0.0 0.00028 20.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PXF49842.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 PXF49842.1 - 0.0097 15.5 0.5 3 7.4 0.3 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 PXF49842.1 - 0.07 13.0 0.1 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 PXF49842.1 - 0.13 12.7 5.7 0.091 13.1 0.5 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 PXF49842.1 - 0.13 12.8 0.5 0.62 10.6 0.2 2.2 2 1 1 3 3 3 0 AAA domain DUF5343 PF17278.2 PXF49843.1 - 0.027 14.5 0.1 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5343) FBPase PF00316.20 PXF49844.1 - 7.8e-69 230.9 0.2 1.1e-68 230.4 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain C2 PF00168.30 PXF49845.1 - 4e-09 36.7 0.4 2e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 C2 domain TGT PF01702.18 PXF49846.1 - 9.2e-141 469.0 0.0 1.1e-140 468.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Myb_DNA-binding PF00249.31 PXF49847.1 - 1.8e-35 120.9 2.4 1.5e-16 60.3 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF49847.1 - 1.5e-27 95.6 0.8 1.7e-15 57.0 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 PXF49847.1 - 0.0024 17.9 0.1 1.3 9.2 0.1 2.7 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 PXF49847.1 - 0.0032 17.5 0.0 0.38 10.8 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 PXF49847.1 - 0.014 15.2 0.0 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 PXF49847.1 - 0.048 13.8 0.0 0.15 12.3 0.0 1.9 1 1 1 2 2 2 0 Rap1 Myb domain DUF5542 PF17696.1 PXF49847.1 - 0.77 9.9 2.1 9.7 6.4 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Myb_DNA-bind_4 PF13837.6 PXF49847.1 - 5.5 7.4 5.8 7.4 7.0 0.3 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain PPR_2 PF13041.6 PXF49848.1 - 4.1e-102 334.2 10.6 1.6e-15 57.0 0.0 13.9 8 5 7 15 15 15 12 PPR repeat family PPR_1 PF12854.7 PXF49848.1 - 2.9e-90 295.6 6.9 1.1e-09 37.9 0.1 15.7 16 1 0 16 16 16 13 PPR repeat PPR PF01535.20 PXF49848.1 - 7.5e-81 260.9 9.6 3.5e-07 30.0 0.0 18.2 17 1 0 17 17 17 14 PPR repeat PPR_3 PF13812.6 PXF49848.1 - 6.8e-78 256.7 0.0 9.9e-14 51.2 0.0 9.8 5 2 4 11 11 11 9 Pentatricopeptide repeat domain PPR_long PF17177.4 PXF49848.1 - 9.4e-49 165.6 4.4 1.8e-12 47.1 0.0 5.6 2 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PXF49848.1 - 1.1e-14 54.2 0.0 0.0015 18.4 0.0 6.4 4 2 1 5 5 5 3 Mitochondrial ATPase expression TPR_14 PF13428.6 PXF49848.1 - 1.1e-06 29.0 3.8 28 5.9 0.0 8.9 12 0 0 12 12 8 0 Tetratricopeptide repeat MRP-S27 PF10037.9 PXF49848.1 - 1.3e-06 27.5 0.0 0.021 13.7 0.0 3.2 3 0 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 PXF49848.1 - 0.00062 20.2 0.4 2.1 8.7 0.0 4.3 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) MNE1 PF13762.6 PXF49848.1 - 0.012 15.6 0.0 84 3.1 0.0 5.0 6 0 0 6 6 6 0 Mitochondrial splicing apparatus component TPR_16 PF13432.6 PXF49848.1 - 0.025 15.2 2.4 8.2 7.2 0.1 4.2 3 1 0 3 3 2 0 Tetratricopeptide repeat Clathrin PF00637.20 PXF49848.1 - 0.049 13.5 0.0 24 4.8 0.0 4.7 5 1 1 6 6 6 0 Region in Clathrin and VPS zf-RING_11 PF17123.5 PXF49850.1 - 4.6e-07 29.5 3.2 4.6e-07 29.5 3.2 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 PXF49850.1 - 3.9e-06 27.1 13.0 3.9e-06 27.1 13.0 2.1 3 0 0 3 3 3 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 PXF49850.1 - 0.012 15.8 4.1 0.027 14.6 4.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 PXF49850.1 - 0.013 15.4 13.1 0.047 13.7 13.1 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 PXF49850.1 - 0.022 14.8 8.6 0.022 14.8 8.6 2.4 2 1 0 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.6 PXF49850.1 - 0.033 14.4 7.7 0.076 13.3 7.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 PXF49850.1 - 0.063 13.6 10.6 0.21 11.9 10.6 2.0 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 PXF49850.1 - 0.76 9.7 16.5 1.7 8.6 14.1 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PXF49850.1 - 2 8.8 13.0 13 6.2 13.0 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain 4PPT_N PF17837.1 PXF49851.1 - 0.029 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain S-AdoMet_synt_C PF02773.16 PXF49852.1 - 7.5e-69 230.0 0.1 2.3e-68 228.5 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 PXF49852.1 - 8.6e-47 158.3 0.0 1.8e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PXF49852.1 - 1.1e-42 144.7 0.1 2.6e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain adh_short PF00106.25 PXF49853.1 - 1.3e-25 90.0 0.0 4.2e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PXF49853.1 - 7e-17 61.8 0.0 2.2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF49853.1 - 6.2e-07 29.5 0.0 9.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PXF49853.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PXF49853.1 - 0.0013 18.2 0.0 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PXF49853.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF5465 PF17553.2 PXF49853.1 - 0.076 13.5 0.4 28 5.6 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5465) Thioredoxin PF00085.20 PXF49854.1 - 7.1e-21 74.1 0.1 9.3e-21 73.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PXF49854.1 - 3.3e-06 27.5 0.1 7.9e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PXF49854.1 - 3.6e-06 26.8 0.0 4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PXF49854.1 - 1.2e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 PXF49854.1 - 0.00013 21.8 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 PXF49854.1 - 0.00041 20.1 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 PXF49854.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 PXF49854.1 - 0.0098 16.1 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF49854.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 PXF49854.1 - 0.053 13.5 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 PXF49854.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) OST3_OST6 PF04756.13 PXF49854.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AAA_2 PF07724.14 PXF49855.1 - 4.5e-56 189.6 0.9 5.6e-52 176.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PXF49855.1 - 1e-31 109.0 12.8 2.1e-30 104.7 9.4 3.4 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 PXF49855.1 - 2.9e-26 91.3 0.2 1.6e-25 88.9 0.2 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 PXF49855.1 - 1.5e-25 90.2 0.0 2.7e-13 50.5 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PXF49855.1 - 4.3e-15 55.9 0.0 5.5e-10 39.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PXF49855.1 - 5.9e-10 39.8 4.3 9.9e-05 22.8 0.2 4.5 3 2 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 PXF49855.1 - 1.3e-09 38.0 0.0 1.8e-05 24.5 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 PXF49855.1 - 1.5e-07 31.8 1.0 0.027 14.7 0.0 4.5 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.6 PXF49855.1 - 3.4e-07 30.9 1.6 0.0056 17.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain Clp_N PF02861.20 PXF49855.1 - 4.6e-07 29.9 4.2 0.00091 19.3 1.3 3.3 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component IstB_IS21 PF01695.17 PXF49855.1 - 5.3e-07 29.5 0.0 0.044 13.5 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 PXF49855.1 - 1.4e-05 24.5 0.0 0.0091 15.4 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 PXF49855.1 - 1.9e-05 24.4 0.9 0.93 9.2 0.3 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PXF49855.1 - 6.2e-05 23.0 0.0 0.18 11.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 PXF49855.1 - 6.8e-05 23.2 0.0 0.22 11.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 PXF49855.1 - 7.6e-05 22.7 0.7 0.052 13.5 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 PXF49855.1 - 0.00014 21.9 0.0 0.37 10.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 PXF49855.1 - 0.00019 21.4 2.6 4 7.3 0.0 4.5 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea Roc PF08477.13 PXF49855.1 - 0.00021 21.5 0.0 0.12 12.6 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 PXF49855.1 - 0.0003 20.3 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 PXF49855.1 - 0.00033 21.2 2.2 0.06 13.9 0.0 3.8 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 PXF49855.1 - 0.00064 20.0 0.6 0.8 9.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PXF49855.1 - 0.00078 19.6 0.0 0.64 10.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PXF49855.1 - 0.00079 19.2 0.0 1.6 8.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 PXF49855.1 - 0.0022 17.9 0.0 0.6 10.0 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PXF49855.1 - 0.003 17.6 0.0 3 7.9 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 PXF49855.1 - 0.0043 17.2 0.0 0.06 13.4 0.0 2.4 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 PXF49855.1 - 0.0053 16.1 0.0 2.7 7.2 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 PXF49855.1 - 0.0065 15.9 0.0 6.8 6.0 0.0 3.3 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 PXF49855.1 - 0.018 14.9 0.0 6.3 6.6 0.0 3.6 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_17 PF13207.6 PXF49855.1 - 0.019 15.4 2.9 1.6 9.2 0.0 3.7 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 PXF49855.1 - 0.026 14.5 0.0 15 5.5 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 PXF49855.1 - 0.056 13.2 0.0 30 4.3 0.0 3.7 4 0 0 4 4 4 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 PXF49855.1 - 0.075 12.9 0.1 7.6 6.4 0.0 2.9 3 0 0 3 3 2 0 NTPase Ras PF00071.22 PXF49855.1 - 0.093 12.3 0.0 23 4.6 0.0 3.7 3 0 0 3 3 3 0 Ras family AAA_19 PF13245.6 PXF49855.1 - 0.093 13.1 0.0 5.9 7.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PXF49855.1 - 0.099 12.2 2.2 0.83 9.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 PXF49855.1 - 0.13 12.0 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mrpl_C PF18502.1 PXF49855.1 - 0.25 11.6 3.5 0.87 9.9 3.5 1.9 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain Cytidylate_kin PF02224.18 PXF49855.1 - 0.39 10.4 11.3 3 7.5 0.0 4.4 4 1 0 5 5 4 0 Cytidylate kinase DUF5401 PF17380.2 PXF49855.1 - 1.8 6.6 17.1 3.6 5.5 17.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5401) GIY-YIG PF01541.24 PXF49856.1 - 0.091 13.1 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 GIY-YIG catalytic domain Sulfotransfer_2 PF03567.14 PXF49857.1 - 1.5e-26 93.8 1.6 2.3e-26 93.2 1.6 1.3 1 0 0 1 1 1 1 Sulfotransferase family PAXNEB PF05625.11 PXF49859.1 - 4.2e-35 121.6 0.0 5.3e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Asp_Glu_race PF01177.22 PXF49859.1 - 0.037 13.9 0.4 0.061 13.2 0.4 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Sulfotransfer_2 PF03567.14 PXF49860.1 - 3.8e-06 27.0 1.0 6.9e-06 26.1 1.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family DUF3336 PF11815.8 PXF49860.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) MFS_5 PF05631.14 PXF49861.1 - 6.4e-111 370.7 12.7 9.6e-111 370.1 12.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Dus PF01207.17 PXF49861.1 - 4.7e-52 177.0 0.0 6.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MFS_1 PF07690.16 PXF49861.1 - 1.6e-16 60.2 42.1 2.3e-15 56.4 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily O-antigen_lig PF13425.6 PXF49861.1 - 0.31 9.8 7.3 0.09 11.5 4.4 1.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein LSM PF01423.22 PXF49862.1 - 9.2e-21 73.3 0.1 1.1e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Spec3 PF15795.5 PXF49863.1 - 2.9e-09 37.3 9.4 5.8e-07 30.0 9.4 2.1 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein Glycophorin_A PF01102.18 PXF49863.1 - 0.051 13.8 0.0 0.098 12.9 0.0 1.5 2 0 0 2 2 2 0 Glycophorin A RRM_1 PF00076.22 PXF49864.1 - 3.8e-13 49.1 0.0 1.6e-05 24.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PXF49864.1 - 0.024 15.7 1.6 0.064 14.4 0.0 2.1 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Ribosomal_S27e PF01667.17 PXF49864.1 - 0.14 11.9 0.3 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S27 S10_plectin PF03501.15 PXF49865.1 - 3.3e-40 136.1 0.3 3.8e-40 135.8 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain RQC PF09382.10 PXF49865.1 - 0.042 13.6 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 RQC domain CoaE PF01121.20 PXF49866.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase EzrA PF06160.12 PXF49867.1 - 0.012 13.8 1.5 0.017 13.3 1.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 PXF49867.1 - 0.02 15.1 0.3 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NAM-associated PF14303.6 PXF49867.1 - 3.4 8.4 12.9 0.58 10.9 5.9 2.6 2 1 1 3 3 3 0 No apical meristem-associated C-terminal domain Dexa_ind PF15198.6 PXF49868.1 - 0.059 13.5 2.1 0.09 12.9 2.1 1.2 1 0 0 1 1 1 0 Dexamethasone-induced DHQ_synthase PF01761.20 PXF49869.1 - 3.1e-62 210.1 0.0 4.6e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 PXF49869.1 - 4.4e-08 33.1 0.0 4.6e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 PXF49869.1 - 0.002 17.0 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase VCBS PF13517.6 PXF49870.1 - 2.5e-28 98.5 35.5 1.1e-10 42.0 5.8 5.6 2 1 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PXF49870.1 - 7.5e-11 42.0 17.4 0.0088 16.2 0.3 5.7 5 0 0 5 5 5 5 FG-GAP repeat UnbV_ASPIC PF07593.12 PXF49870.1 - 0.00042 20.2 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 ASPIC and UnbV MFS_1 PF07690.16 PXF49871.1 - 1.2e-20 73.8 22.5 1.2e-20 73.8 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PXF49871.1 - 2.1e-15 56.2 5.0 2.1e-15 56.2 5.0 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 PXF49871.1 - 4.6e-05 21.8 0.2 7e-05 21.2 0.2 1.2 1 0 0 1 1 1 1 BT1 family DUF981 PF06168.11 PXF49871.1 - 0.17 11.8 16.6 0.81 9.6 4.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF981) DUF4271 PF14093.6 PXF49871.1 - 2 8.2 6.2 22 4.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) DUF2964 PF11177.8 PXF49871.1 - 5.5 7.3 7.4 1.9 8.7 2.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2964) Peptidase_S41 PF03572.18 PXF49872.1 - 1.8e-46 157.8 0.6 9.9e-46 155.3 0.0 2.4 3 0 0 3 3 3 1 Peptidase family S41 PDZ_6 PF17820.1 PXF49872.1 - 2.5e-10 40.0 0.0 6.9e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PXF49872.1 - 1.4e-05 25.3 0.1 2.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PXF49872.1 - 1.9e-05 24.9 0.1 4.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain MbeB_N PF04837.12 PXF49872.1 - 0.037 14.3 0.2 0.12 12.7 0.2 1.9 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Tricorn_PDZ PF14685.6 PXF49872.1 - 0.046 13.7 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain Methyltransf_23 PF13489.6 PXF49873.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PXF49873.1 - 5.5e-05 23.8 0.0 0.0001 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49873.1 - 0.00022 21.8 0.0 0.0006 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF49873.1 - 0.022 15.4 0.0 0.054 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 PXF49873.1 - 0.059 13.2 0.0 0.098 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PXF49873.1 - 0.072 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PRK PF00485.18 PXF49874.1 - 1.3e-08 34.8 0.0 3.6e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 PXF49874.1 - 0.0047 16.6 0.0 0.0067 16.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Str_synth PF03088.16 PXF49875.1 - 1.9e-13 50.3 0.0 2e-12 47.1 0.0 2.5 2 1 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 PXF49875.1 - 8.7e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PXF49875.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 2.0 1 1 0 1 1 1 1 Arylesterase NHL PF01436.21 PXF49875.1 - 0.014 15.4 0.6 8.2 6.7 0.1 3.7 3 0 0 3 3 3 0 NHL repeat DUF5018 PF16410.5 PXF49875.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Syja_N PF02383.18 PXF49876.1 - 8.8e-66 222.4 0.0 1.5e-65 221.6 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Stathmin PF00836.19 PXF49876.1 - 0.1 12.6 0.2 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 Stathmin family Raftlin PF15250.6 PXF49876.1 - 1.3 7.7 5.3 2.2 6.9 5.3 1.2 1 0 0 1 1 1 0 Raftlin HAD_2 PF13419.6 PXF49877.1 - 8.2e-28 97.7 0.0 9.4e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PXF49877.1 - 1.2e-18 68.2 0.1 4.5e-18 66.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PXF49877.1 - 0.00018 22.0 0.0 0.00045 20.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PXF49877.1 - 0.02 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Polysacc_deac_2 PF04748.13 PXF49877.1 - 0.061 12.5 0.1 0.097 11.8 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Acid_phosphat_B PF03767.14 PXF49877.1 - 0.18 11.4 0.0 3.1 7.3 0.0 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 PXF49877.1 - 0.21 11.3 0.0 2.2 8.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UBA PF00627.31 PXF49878.1 - 5.9e-08 32.5 0.1 9.2e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 PXF49878.1 - 7e-07 29.4 6.4 7e-07 29.4 6.4 1.5 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 PXF49878.1 - 0.002 18.1 10.2 0.004 17.1 10.2 1.6 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 PXF49878.1 - 0.047 14.2 1.3 0.098 13.2 0.7 2.0 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) UBA_4 PF14555.6 PXF49878.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Cut8 PF08559.10 PXF49879.1 - 2.9e-16 59.8 2.1 2.9e-16 59.8 2.1 1.7 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein Pkinase PF00069.25 PXF49880.1 - 7.8e-61 205.7 0.0 1.1e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF49880.1 - 2.4e-32 112.2 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PXF49880.1 - 1.4e-05 24.2 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PXF49880.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PXF49880.1 - 0.019 14.9 0.4 0.23 11.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 PXF49880.1 - 0.062 12.3 0.1 0.095 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.32 PXF49881.1 - 1.3e-13 51.2 9.6 0.0029 18.4 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 PXF49881.1 - 0.00078 19.3 0.1 0.044 13.7 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 PXF49881.1 - 0.0019 18.5 0.0 5.9 7.3 0.0 3.6 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1258 PF06869.12 PXF49886.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) ApoLp-III PF07464.11 PXF49889.1 - 0.0025 17.9 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) DUF3027 PF11228.8 PXF49889.1 - 0.081 12.9 1.0 4.5 7.2 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3027) Meckelin PF09773.9 PXF49889.1 - 0.24 9.4 2.4 0.24 9.4 1.4 1.4 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) HSBP1 PF06825.12 PXF49889.1 - 0.51 10.2 2.8 3.3 7.6 1.2 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PRY PF13765.6 PXF49891.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SPRY-associated domain SOG2 PF10428.9 PXF49892.1 - 0.055 12.7 2.1 0.062 12.5 2.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PEN-2 PF10251.9 PXF49893.1 - 0.088 13.2 0.5 4.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase HTH_1 PF00126.27 PXF49894.1 - 0.23 11.4 3.9 3.7 7.6 0.5 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Ldh_1_N PF00056.23 PXF49895.1 - 1.1e-31 109.9 0.2 2.5e-31 108.7 0.2 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PXF49895.1 - 3e-28 98.9 0.0 5.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Syndecan PF01034.20 PXF49896.1 - 0.056 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain Asn_synthase PF00733.21 PXF49897.1 - 8.8e-86 288.7 1.0 4.6e-54 184.4 0.3 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PXF49897.1 - 3.6e-31 107.6 0.0 6e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PXF49897.1 - 5.2e-22 78.5 0.1 1.1e-21 77.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 PXF49897.1 - 2.8e-07 30.2 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 PXF49897.1 - 1.4e-05 24.4 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 PXF49897.1 - 0.03 13.1 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 PXF49897.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ASC PF00858.24 PXF49898.1 - 0.00033 19.8 0.8 0.0016 17.5 0.1 2.0 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel ASC PF00858.24 PXF49899.1 - 9.1e-07 28.2 0.2 0.015 14.3 0.0 2.1 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel Rod_cone_degen PF15201.6 PXF49900.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Progressive rod-cone degeneration Aminotran_3 PF00202.21 PXF49901.1 - 9.4e-68 228.7 0.0 1.2e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Glycos_transf_2 PF00535.26 PXF49902.1 - 3.3e-07 30.3 0.0 7.5e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PXF49902.1 - 0.0061 16.5 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 PXF49902.1 - 0.0069 16.1 0.6 0.12 12.1 0.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family H_PPase PF03030.16 PXF49904.1 - 1.6e-12 46.9 4.8 1.6e-12 46.9 4.8 1.6 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase MAP17 PF15807.5 PXF49904.1 - 0.13 12.5 2.6 3.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3611 PF12263.8 PXF49904.1 - 0.61 10.0 7.2 1.4 8.7 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3611) SNF2_N PF00176.23 PXF49905.1 - 3.8e-71 239.6 0.2 6.2e-71 238.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 PXF49905.1 - 3.3e-36 123.8 6.5 5.9e-36 123.0 1.7 3.4 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 PXF49905.1 - 4.6e-18 65.6 0.0 3.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF49905.1 - 4.7e-08 33.2 0.0 2.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PXF49905.1 - 2.9e-06 27.2 0.0 8.1e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 PXF49905.1 - 9e-06 25.8 2.7 0.037 14.2 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 PXF49905.1 - 7.3e-05 22.1 0.0 0.0002 20.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 PXF49905.1 - 0.00049 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HAND PF09110.11 PXF49905.1 - 0.004 17.9 0.8 0.004 17.9 0.8 3.1 3 0 0 3 3 3 1 HAND AbiJ_NTD5 PF18865.1 PXF49905.1 - 3 7.7 5.7 13 5.6 0.3 3.8 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 PseudoU_synth_2 PF00849.22 PXF49906.1 - 5.7e-25 88.3 0.0 8.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ChaC PF04752.12 PXF49907.1 - 1.2e-43 149.2 0.7 1.4e-43 149.0 0.7 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 PXF49907.1 - 0.091 13.4 0.1 0.18 12.4 0.1 1.6 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like BACK PF07707.15 PXF49908.1 - 2.4e-19 69.3 1.4 4.4e-19 68.5 1.4 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 PXF49908.1 - 3.6e-08 33.6 0.1 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain RTTN_N PF14726.6 PXF49908.1 - 0.061 14.1 0.3 0.12 13.2 0.3 1.4 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning MATH PF00917.26 PXF49908.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 MATH domain Ribosomal_L7Ae PF01248.26 PXF49909.1 - 3e-23 81.3 0.0 3.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.7 PXF49909.1 - 0.045 14.5 0.0 0.072 13.8 0.0 1.3 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Noc2 PF03715.13 PXF49910.1 - 1.8e-74 250.7 0.0 5e-74 249.2 0.0 1.7 2 0 0 2 2 2 1 Noc2p family LRR_4 PF12799.7 PXF49911.1 - 5.6e-37 125.1 40.1 1.9e-07 31.3 2.9 7.5 2 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PXF49911.1 - 5.3e-27 93.4 36.7 3.1e-11 42.9 2.6 6.6 2 2 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 PXF49911.1 - 1.9e-17 63.3 18.8 5.5e-07 29.2 2.1 3.5 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PXF49911.1 - 7.6e-06 25.8 35.3 3.1 8.7 0.9 10.5 9 3 1 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 PXF49911.1 - 0.00017 21.4 22.6 0.067 13.3 0.1 8.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_5 PF13306.6 PXF49911.1 - 0.012 15.6 1.5 0.012 15.6 1.5 2.1 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) 2OG-FeII_Oxy PF03171.20 PXF49912.1 - 0.00038 20.9 0.0 0.00065 20.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 PXF49912.1 - 0.0004 21.1 0.0 0.00095 19.9 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GST_N PF02798.20 PXF49912.1 - 0.004 17.5 0.0 0.018 15.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Nop PF01798.18 PXF49913.1 - 1.6e-51 175.0 0.1 9.6e-51 172.5 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 PXF49913.1 - 3.5e-22 79.6 4.7 3.5e-22 79.6 4.7 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Transposase_24 PF03004.14 PXF49913.1 - 0.051 13.7 0.5 0.051 13.7 0.5 1.8 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Med4 PF10018.9 PXF49914.1 - 7.9e-20 71.4 0.2 1.3e-19 70.6 0.1 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 PKS_DE PF18369.1 PXF49914.1 - 0.05 14.2 0.6 1.3 9.6 0.1 2.4 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain DUF4363 PF14276.6 PXF49914.1 - 0.074 13.2 0.8 0.15 12.2 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) DALR_1 PF05746.15 PXF49914.1 - 0.1 12.8 0.3 0.6 10.3 0.1 2.0 1 1 1 2 2 2 0 DALR anticodon binding domain NBP1 PF08537.10 PXF49914.1 - 0.16 11.4 2.1 0.18 11.2 2.1 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Reprolysin_4 PF13583.6 PXF49916.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 4F5 PF04419.14 PXF49918.1 - 0.00017 22.4 32.0 0.063 14.2 32.0 2.4 1 1 0 1 1 1 1 4F5 protein family TAF4 PF05236.14 PXF49918.1 - 1.1 8.9 17.3 1.3 8.8 17.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Nipped-B_C PF12830.7 PXF49919.1 - 1.6e-14 54.3 0.0 2.2e-13 50.6 0.0 2.9 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 PXF49919.1 - 1.4e-10 41.3 0.5 0.016 15.5 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 PXF49919.1 - 2.8e-05 24.0 16.5 0.18 12.2 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat Cnd1 PF12717.7 PXF49919.1 - 9.8e-05 22.4 0.3 6.7 6.7 0.0 5.1 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PXF49919.1 - 0.00053 20.5 0.4 4.8 7.9 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 PXF49919.1 - 0.0078 16.6 7.1 2.3 8.7 0.0 4.6 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PXF49919.1 - 0.037 14.5 5.5 17 6.0 0.0 5.3 4 1 2 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 PXF49919.1 - 0.086 12.4 2.2 3.7 7.1 0.0 3.8 2 2 2 4 4 4 0 CLASP N terminal Amino_oxidase PF01593.24 PXF49920.1 - 4.8e-40 138.2 0.0 4.3e-39 135.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF49920.1 - 1.6e-15 57.0 0.3 3.3e-15 56.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF49920.1 - 2.5e-10 40.5 7.4 4.8e-06 26.4 4.7 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PXF49920.1 - 6.4e-07 28.9 0.8 1.5e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF49920.1 - 2.5e-06 26.8 4.5 4.7e-06 25.9 4.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 PXF49920.1 - 1e-05 26.0 1.7 0.0002 21.9 1.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PXF49920.1 - 1e-05 24.9 0.2 0.00023 20.5 0.8 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 PXF49920.1 - 4.3e-05 22.4 0.5 7.4e-05 21.6 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 PXF49920.1 - 0.00012 21.5 1.0 0.00018 20.9 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PXF49920.1 - 0.00069 19.1 2.8 0.0011 18.4 2.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF49920.1 - 0.00089 18.4 0.8 0.0018 17.4 0.8 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PXF49920.1 - 0.0013 18.0 0.3 0.0023 17.3 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PXF49920.1 - 0.0044 16.2 2.1 0.0073 15.4 2.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PXF49920.1 - 0.021 14.1 0.8 0.021 14.1 0.8 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 PXF49920.1 - 0.037 12.8 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 MCRA family 3HCDH_N PF02737.18 PXF49920.1 - 0.082 12.8 1.1 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 PXF49920.1 - 0.16 12.2 0.2 0.32 11.3 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain FMO-like PF00743.19 PXF49920.1 - 0.27 9.6 0.1 0.43 8.9 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Hint PF01079.20 PXF49921.1 - 2.9e-30 105.4 0.1 5.9e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Hint module Vint PF14623.6 PXF49921.1 - 0.0092 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Hint-domain RTC_insert PF05189.13 PXF49921.1 - 0.18 12.4 0.0 0.57 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain AAA_12 PF13087.6 PXF49922.1 - 9e-58 195.2 0.0 3.3e-57 193.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PXF49922.1 - 2.4e-57 194.7 0.4 2.4e-57 194.7 0.4 3.0 3 0 0 3 3 3 1 AAA domain SEN1_N PF12726.7 PXF49922.1 - 3.5e-14 52.0 4.3 6.5e-14 51.1 4.3 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 PXF49922.1 - 9.3e-08 32.0 0.0 0.033 13.9 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 PXF49922.1 - 1.3e-06 28.8 0.1 1.3e-05 25.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 PXF49922.1 - 0.00043 20.3 0.1 0.55 10.2 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PXF49922.1 - 0.00051 20.3 0.3 0.67 10.2 0.1 4.1 2 1 1 3 3 3 1 AAA domain DUF2075 PF09848.9 PXF49922.1 - 0.00073 18.9 0.3 0.22 10.7 0.0 2.9 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 PXF49922.1 - 0.00082 19.0 0.0 0.059 12.9 0.0 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 PXF49922.1 - 0.00083 19.2 6.1 0.46 10.2 0.0 4.7 6 1 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 PXF49922.1 - 0.0097 16.4 0.3 0.028 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 PXF49922.1 - 0.021 14.7 0.0 1.2 9.0 0.0 3.3 3 1 0 3 3 3 0 Helicase COG5 PF10392.9 PXF49922.1 - 0.034 14.3 2.4 0.1 12.8 2.4 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 GvpD PF07088.11 PXF49922.1 - 0.056 12.1 0.1 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 PXF49922.1 - 0.082 13.3 0.0 0.44 10.9 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain DUF5405 PF17399.2 PXF49922.1 - 0.19 12.0 0.6 0.64 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) bZIP_2 PF07716.15 PXF49924.1 - 0.00051 20.1 5.9 0.0017 18.4 6.0 1.8 1 1 0 1 1 1 1 Basic region leucine zipper DUF5528 PF17666.1 PXF49924.1 - 0.0022 18.0 0.1 0.0064 16.5 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5528) bZIP_1 PF00170.21 PXF49924.1 - 0.089 12.9 3.5 0.24 11.5 3.5 1.7 1 0 0 1 1 1 0 bZIP transcription factor TPR_12 PF13424.6 PXF49927.1 - 1.2e-08 35.1 4.4 0.00094 19.4 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PXF49927.1 - 2.1e-05 24.2 7.2 0.0019 18.0 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PXF49927.1 - 7.8e-05 23.1 1.6 0.5 10.9 0.9 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PXF49927.1 - 0.00016 22.2 9.2 0.029 15.0 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.6 PXF49927.1 - 0.00045 19.7 0.4 0.00064 19.2 0.4 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 PXF49927.1 - 0.0023 18.2 0.1 0.24 11.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 PXF49927.1 - 0.0056 17.2 0.1 4.7 8.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PXF49927.1 - 0.01 15.8 0.3 0.26 11.4 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PXF49927.1 - 0.011 15.8 0.5 11 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PXF49927.1 - 0.038 13.8 1.5 0.68 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PXF49927.1 - 0.048 13.8 10.5 0.1 12.8 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF49927.1 - 0.083 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 PXF49927.1 - 0.11 13.3 4.2 2.8 9.0 0.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat FTHFS PF01268.19 PXF49928.1 - 5.8e-247 820.3 0.0 6.5e-247 820.2 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase DUF188 PF02639.14 PXF49928.1 - 0.034 13.8 0.2 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized BCR, YaiI/YqxD family COG1671 PBP-Tp47_a PF14889.6 PXF49928.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a EloA-BP1 PF15870.5 PXF49929.1 - 0.017 15.4 0.1 0.017 15.4 0.1 3.0 4 1 0 4 4 4 0 ElonginA binding-protein 1 KIX_2 PF16987.5 PXF49929.1 - 0.038 14.0 0.1 0.092 12.7 0.1 1.7 1 0 0 1 1 1 0 KIX domain SnoaL_3 PF13474.6 PXF49930.1 - 1.3e-13 51.2 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 PXF49930.1 - 0.00015 22.3 0.0 0.00026 21.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 PXF49930.1 - 0.00026 21.5 0.0 0.00044 20.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 PXF49930.1 - 0.0005 20.4 0.0 0.00079 19.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) UVR PF02151.19 PXF49930.1 - 0.0037 16.9 3.0 0.0066 16.1 3.0 1.4 1 0 0 1 1 1 1 UvrB/uvrC motif GrpE PF01025.19 PXF49930.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 GrpE SnoaL PF07366.12 PXF49930.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Spectrin_like PF18373.1 PXF49930.1 - 0.039 14.0 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Spectrin like domain Lactonase PF10282.9 PXF49931.1 - 2.1e-44 152.2 0.0 2.5e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF2633 PF11119.8 PXF49931.1 - 0.95 9.4 3.2 2.3 8.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Glyco_hydro_47 PF01532.20 PXF49932.1 - 2.5e-82 277.2 0.0 3.7e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UCH PF00443.29 PXF49933.1 - 2.6e-47 161.5 0.0 4.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PXF49933.1 - 4.6e-16 59.3 10.4 7.9e-16 58.5 6.2 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PXF49933.1 - 6.2e-10 39.3 5.7 6.2e-10 39.3 5.7 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 PXF49933.1 - 0.00013 21.5 0.3 0.43 10.0 0.2 3.1 4 0 0 4 4 4 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Dala_Dala_lig_N PF01820.21 PXF49933.1 - 0.11 12.9 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Ribosomal_S27e PF01667.17 PXF49933.1 - 6.4 6.6 7.1 5.2 6.9 3.4 2.7 2 0 0 2 2 2 0 Ribosomal protein S27 AAA PF00004.29 PXF49934.1 - 3.9e-41 140.6 0.1 1.1e-40 139.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF49934.1 - 2.4e-11 43.2 0.0 6.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PXF49934.1 - 2e-05 24.6 0.1 8.5e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PXF49934.1 - 2.2e-05 24.9 0.1 0.00088 19.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PXF49934.1 - 3.7e-05 24.0 0.0 0.0067 16.7 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 PXF49934.1 - 5.4e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PXF49934.1 - 0.00046 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PXF49934.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 PXF49934.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 PXF49934.1 - 0.0032 17.6 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PXF49934.1 - 0.0036 17.6 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PXF49934.1 - 0.0081 16.1 0.1 0.55 10.1 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 PXF49934.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PXF49934.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PXF49934.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 PXF49934.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 PXF49934.1 - 0.025 14.3 0.0 0.08 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PXF49934.1 - 0.039 14.0 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PXF49934.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PXF49934.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PXF49934.1 - 0.054 12.8 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 PXF49934.1 - 0.069 12.9 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PXF49934.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PXF49934.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 PXF49934.1 - 0.14 11.6 0.3 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 PXF49934.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA-synt_1e PF01406.19 PXF49935.1 - 6.9e-120 400.0 0.1 1e-119 399.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PXF49935.1 - 1.6e-09 37.0 2.4 0.00077 18.3 0.8 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PXF49935.1 - 0.0053 15.1 0.7 0.025 12.8 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 PXF49935.1 - 0.056 13.9 1.9 0.092 13.2 0.0 2.4 2 0 0 2 2 2 0 DALR domain tRNA-synt_1c PF00749.21 PXF49935.1 - 0.16 10.9 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PGA2 PF07543.12 PXF49935.1 - 0.34 10.9 8.8 0.69 9.9 8.8 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Pribosyltran PF00156.27 PXF49936.1 - 7.3e-10 38.6 0.1 3.6e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain ANAPC4_WD40 PF12894.7 PXF49937.1 - 1.7e-07 31.4 0.0 0.47 10.8 0.0 3.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PXF49937.1 - 6.2e-06 26.8 5.4 1.8e-05 25.4 0.4 3.9 3 1 1 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.9 PXF49937.1 - 0.00017 21.4 0.1 0.0004 20.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) eIF2A PF08662.11 PXF49937.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A THF_DHG_CYH_C PF02882.19 PXF49938.1 - 3.1e-68 228.1 1.6 4.2e-68 227.7 1.6 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PXF49938.1 - 5.3e-41 139.5 0.4 7.8e-41 139.0 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 PXF49938.1 - 0.019 13.9 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family UBA_4 PF14555.6 PXF49939.1 - 0.0089 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF1296 PF06972.11 PXF49939.1 - 0.067 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) ABC_membrane PF00664.23 PXF49940.1 - 4.7e-64 216.7 28.2 7.2e-38 130.8 15.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PXF49940.1 - 9.2e-52 175.2 0.3 2.2e-27 96.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PXF49940.1 - 8.8e-08 31.8 19.0 0.013 14.9 0.3 4.7 4 1 1 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PXF49940.1 - 1.7e-06 28.0 0.3 0.77 9.5 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 PXF49940.1 - 3.1e-06 27.2 3.4 0.018 15.1 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PXF49940.1 - 2.1e-05 24.2 3.5 0.035 13.9 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PXF49940.1 - 0.0003 21.2 0.8 0.61 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 PXF49940.1 - 0.00051 19.8 1.9 1.5 8.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PXF49940.1 - 0.00088 19.1 0.0 0.34 10.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 PXF49940.1 - 0.0013 18.0 0.8 1.1 8.3 0.3 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 PXF49940.1 - 0.0015 19.1 5.0 0.65 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 PXF49940.1 - 0.002 18.0 4.8 0.045 13.7 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 PXF49940.1 - 0.0028 17.8 5.8 0.21 11.6 0.8 3.0 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 PXF49940.1 - 0.011 15.8 9.3 0.056 13.5 0.2 3.2 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 PXF49940.1 - 0.016 14.4 2.5 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 PXF49940.1 - 0.019 14.5 1.1 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 PXF49940.1 - 0.023 14.5 2.3 1.7 8.4 1.7 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 PXF49940.1 - 0.042 13.1 1.1 1 8.6 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 PXF49940.1 - 0.059 13.6 0.3 16 5.7 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PXF49940.1 - 0.06 13.6 6.9 3.2 8.0 0.2 3.3 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 PXF49940.1 - 0.13 11.8 1.2 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 PXF49940.1 - 0.15 10.9 3.0 3.2 6.6 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 PXF49940.1 - 0.17 10.9 0.7 4.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 PXF49940.1 - 0.18 11.7 0.6 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.16 PXF49940.1 - 0.27 10.5 2.5 13 5.1 0.2 2.6 2 0 0 2 2 2 0 AIG1 family FtsK_SpoIIIE PF01580.18 PXF49940.1 - 1 8.7 3.6 10 5.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MeaB PF03308.16 PXF49940.1 - 1.1 8.2 3.5 8.3 5.3 0.4 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 PXF49940.1 - 1.8 8.5 5.8 7 6.5 0.1 3.2 4 0 0 4 4 3 0 NACHT domain Methyltransf_31 PF13847.6 PXF49941.1 - 4.8e-28 97.9 0.0 9.7e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PXF49941.1 - 5e-18 65.6 0.1 1.4e-17 64.1 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF49941.1 - 1.6e-16 60.7 0.0 4.5e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PXF49941.1 - 2.1e-12 47.2 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PXF49941.1 - 2.4e-09 36.9 0.0 7.1e-09 35.3 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PXF49941.1 - 3.4e-09 37.4 0.0 9.3e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PXF49941.1 - 0.00036 20.5 0.3 0.0046 16.8 0.1 2.2 1 1 1 2 2 2 1 Hypothetical methyltransferase PCMT PF01135.19 PXF49941.1 - 0.00085 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PXF49941.1 - 0.0036 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 PXF49941.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 PXF49941.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 PXF49941.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB NTPase_P4 PF11602.8 PXF49941.1 - 0.082 12.1 0.6 0.15 11.3 0.6 1.4 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Methyltransf_4 PF02390.17 PXF49941.1 - 0.1 12.1 0.0 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Abhydrolase_6 PF12697.7 PXF49942.1 - 6.5e-05 23.6 0.1 0.0002 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PXF49942.1 - 0.0002 21.1 0.0 0.0044 16.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 PXF49942.1 - 0.00098 19.1 0.0 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 PXF49942.1 - 0.004 16.5 0.0 0.038 13.2 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Acyltransferase PF01553.21 PXF49942.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase COesterase PF00135.28 PXF49942.1 - 0.048 12.5 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DAGAT PF03982.13 PXF49942.1 - 0.054 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase zf-UBR PF02207.20 PXF49943.1 - 1.7e-07 31.3 9.8 1.7e-07 31.3 9.8 3.2 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 PXF49943.1 - 1.8e-05 24.5 9.7 1.8e-05 24.5 9.7 3.3 3 0 0 3 3 3 2 PHD-finger Vma12 PF11712.8 PXF49944.1 - 0.17 12.0 3.1 0.57 10.2 3.0 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Med3 PF11593.8 PXF49944.1 - 4.6 6.3 14.9 5.5 6.1 14.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arm PF00514.23 PXF49945.1 - 8.2e-18 63.8 37.9 1e-05 25.4 0.1 10.1 11 0 0 11 11 11 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PXF49945.1 - 1.3e-07 31.9 17.2 0.11 12.9 0.1 7.4 4 2 4 9 9 9 6 HEAT repeats HEAT PF02985.22 PXF49945.1 - 6e-06 26.1 32.7 1.5 9.3 0.0 10.8 13 0 0 13 13 13 4 HEAT repeat V-ATPase_H_C PF11698.8 PXF49945.1 - 5.2e-05 23.3 4.8 36 4.5 0.0 6.4 5 2 3 8 8 8 0 V-ATPase subunit H HEAT_EZ PF13513.6 PXF49945.1 - 0.0015 19.0 30.0 0.37 11.3 0.7 8.5 7 3 3 10 10 10 5 HEAT-like repeat Arm_2 PF04826.13 PXF49945.1 - 0.008 15.7 0.4 0.086 12.3 0.1 2.4 2 0 0 2 2 2 1 Armadillo-like DUF3361 PF11841.8 PXF49945.1 - 0.033 14.1 5.5 0.47 10.4 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 PXF49947.1 - 1.4e-09 38.2 8.6 0.0026 18.1 0.3 4.2 1 1 5 6 6 6 6 HEAT repeats HEAT PF02985.22 PXF49947.1 - 2.2e-07 30.5 4.4 0.88 10.0 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.7 PXF49947.1 - 3.5e-07 30.4 0.3 0.00034 20.7 0.0 2.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PXF49947.1 - 5.8e-05 21.9 0.9 0.12 10.9 0.1 2.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 PXF49947.1 - 0.013 16.0 11.0 0.78 10.3 1.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat Vac14_Fig4_bd PF11916.8 PXF49947.1 - 0.015 14.9 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding RuvX PF03652.15 PXF49948.1 - 2.8e-08 34.2 0.0 3.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase CAP_GLY PF01302.25 PXF49949.1 - 4.8e-20 71.4 1.2 1.2e-19 70.1 1.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 PXF49949.1 - 4.7e-09 36.4 0.1 0.0062 16.9 0.0 4.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PXF49949.1 - 2.4e-06 27.2 0.1 0.0031 17.2 0.0 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 PXF49949.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat DUF1515 PF07439.11 PXF49949.1 - 0.0039 17.2 1.2 0.012 15.6 0.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1515) Bromodomain PF00439.25 PXF49950.1 - 2.2e-15 56.5 0.0 4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PXF49950.1 - 7.1e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bombinin PF05298.11 PXF49950.1 - 0.01 15.5 0.1 0.03 14.0 0.1 1.7 1 0 0 1 1 1 0 Bombinin DUF664 PF04978.12 PXF49950.1 - 0.062 13.7 3.0 0.063 13.7 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF664) Ndc1_Nup PF09531.10 PXF49950.1 - 3.2 6.3 3.9 4.3 5.9 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup G_glu_transpept PF01019.21 PXF49951.1 - 3.3e-123 412.2 0.0 3.8e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase F-box-like PF12937.7 PXF49952.1 - 4e-12 45.8 0.4 4e-12 45.8 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PXF49952.1 - 1.1e-08 34.7 1.5 1.9e-08 34.0 1.2 1.5 1 1 0 1 1 1 1 F-box domain Sel1 PF08238.12 PXF49952.1 - 0.013 16.1 2.2 3.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Sel1 repeat F-box_5 PF18511.1 PXF49952.1 - 0.028 14.0 0.2 0.048 13.2 0.2 1.4 1 0 0 1 1 1 0 F-box Ion_trans PF00520.31 PXF49953.1 - 1.3e-20 73.7 19.4 1.3e-20 73.7 19.4 1.5 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 PXF49953.1 - 2.5e-12 46.7 0.0 5.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PXF49953.1 - 8.3e-12 44.9 11.7 8.3e-12 44.9 11.7 2.5 2 1 0 2 2 2 1 Ion channel Bcr-Abl_Oligo PF09036.10 PXF49953.1 - 0.041 13.9 0.3 0.13 12.3 0.3 1.8 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain NAD_binding_5 PF07994.12 PXF49954.1 - 1.2e-146 488.2 0.0 1.4e-146 487.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PXF49954.1 - 4e-47 159.0 1.2 1.1e-46 157.5 0.6 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Taxilin PF09728.9 PXF49955.1 - 3.1e-21 75.9 58.1 3.1e-21 75.9 58.1 2.3 2 1 0 3 3 3 1 Myosin-like coiled-coil protein DUF5082 PF16888.5 PXF49955.1 - 0.0075 16.5 12.7 0.0075 16.5 12.7 3.3 1 1 1 3 3 3 1 Domain of unknown function (DUF5082) ATG16 PF08614.11 PXF49955.1 - 0.016 15.5 22.1 0.016 15.5 22.1 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Malate_DH PF12434.8 PXF49955.1 - 0.83 9.7 8.5 7.2 6.7 0.1 3.9 3 0 0 3 3 3 0 Malate dehydrogenase enzyme GCR PF02155.15 PXF49955.1 - 1.2 8.1 6.6 0.26 10.3 0.4 2.1 2 0 0 2 2 2 0 Glucocorticoid receptor UPF0242 PF06785.11 PXF49955.1 - 7.3 6.6 60.5 3.7 7.6 10.4 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus IMS PF00817.20 PXF49956.1 - 3.2e-25 88.9 0.0 3.9e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 PXF49957.1 - 6.2e-08 33.4 0.1 1.6e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 PXF49957.1 - 1.3e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 PXF49957.1 - 1.7e-07 31.2 0.6 4.9e-07 29.7 0.2 2.0 2 0 0 2 2 2 1 IMS family HHH motif DUF962 PF06127.11 PXF49960.1 - 4.5e-12 45.9 2.2 7e-12 45.3 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) LUC7 PF03194.15 PXF49961.1 - 5.6e-32 111.4 5.8 3.4e-22 79.3 0.7 2.6 2 1 0 2 2 2 2 LUC7 N_terminus F_bP_aldolase PF01116.20 PXF49962.1 - 1.4e-86 290.4 0.0 1.6e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RAMA PF18755.1 PXF49963.1 - 3.6e-05 24.1 0.1 0.002 18.5 0.1 3.2 1 1 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated DUF1015 PF06245.11 PXF49964.1 - 8.2e-111 370.6 0.0 9.2e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) Metallophos PF00149.28 PXF49966.1 - 5.5e-37 128.3 0.0 8.7e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PALP PF00291.25 PXF49967.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.27 PXF49968.1 - 1.6e-51 174.6 0.0 2.4e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PXF49968.1 - 1.3e-45 154.0 4.7 2.7e-45 152.9 4.7 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PXF49968.1 - 2.5e-22 78.7 0.0 7.6e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF49968.1 - 1.3e-11 44.8 1.9 1.3e-11 44.8 1.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF49968.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 PXF49968.1 - 4.1e-05 23.4 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 PXF49968.1 - 0.00024 21.1 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II Colicin_immun PF09204.10 PXF49968.1 - 0.071 13.6 0.2 3.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity DNA_mis_repair PF01119.19 PXF49969.1 - 9.4e-15 54.3 0.0 2.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 PXF49969.1 - 1.6e-12 47.4 0.1 2.3e-10 40.4 0.0 3.3 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 PXF49969.1 - 8.3e-10 38.6 0.1 2e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PXF49969.1 - 5.5e-06 26.9 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5310 PF17237.2 PXF49969.1 - 4.5 7.2 8.3 6 6.8 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5310) S4 PF01479.25 PXF49970.1 - 2.3e-11 43.2 0.0 4.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PXF49970.1 - 4.7e-07 30.6 4.0 8.6e-07 29.8 3.5 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain RcnB PF11776.8 PXF49970.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Dimer_Tnp_hAT PF05699.14 PXF49971.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region FAM167 PF11652.8 PXF49973.1 - 1.8 9.1 7.2 0.18 12.3 0.6 2.4 2 1 0 2 2 2 0 FAM167 GCFC PF07842.12 PXF49974.1 - 9.8e-18 64.7 0.4 2.7e-17 63.3 0.4 1.7 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 PXF49974.1 - 3e-06 27.0 1.2 6.8e-06 25.9 1.2 1.7 1 0 0 1 1 1 1 G-patch domain DegS PF05384.11 PXF49974.1 - 0.011 15.2 2.0 0.011 15.2 2.0 1.8 2 0 0 2 2 2 0 Sensor protein DegS Fib_alpha PF08702.10 PXF49974.1 - 0.15 12.2 3.7 0.096 12.9 1.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PrmA PF06325.13 PXF49975.1 - 1.7e-66 224.6 0.0 1.9e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PXF49975.1 - 1.4e-09 37.9 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PXF49975.1 - 1.7e-09 37.5 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PXF49975.1 - 5.6e-07 29.6 0.0 8.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PXF49975.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PXF49975.1 - 1.1e-05 26.0 0.0 2.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PXF49975.1 - 4.7e-05 23.2 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 PXF49975.1 - 0.00085 19.1 0.2 0.0019 17.9 0.2 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 PXF49975.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PXF49975.1 - 0.0031 18.1 0.0 0.0056 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PXF49975.1 - 0.0032 17.4 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PXF49975.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 PXF49975.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ada3 PF10198.9 PXF49976.1 - 6.6e-07 29.5 15.4 2.1e-06 27.9 15.4 1.9 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 PPP5 PF08321.12 PXF49976.1 - 0.18 12.1 1.8 0.47 10.8 1.8 1.7 1 0 0 1 1 1 0 PPP5 TPR repeat region PG_binding_1 PF01471.18 PXF49976.1 - 0.24 11.7 1.7 4 7.7 0.0 2.7 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Scm3 PF10384.9 PXF49976.1 - 0.45 10.3 2.3 0.94 9.3 2.3 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 DUF1977 PF09320.11 PXF49976.1 - 1.2 9.4 5.2 13 6.1 1.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1977) adh_short PF00106.25 PXF49977.1 - 9.2e-11 41.6 0.0 3.1e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PXF49977.1 - 4.3e-09 36.3 0.0 7.9e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Dynamin_M PF01031.20 PXF49978.1 - 1.7e-60 204.7 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 PXF49978.1 - 1.7e-28 99.8 0.0 4.4e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PXF49978.1 - 1.9e-06 27.9 0.0 6.8e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PXF49978.1 - 5.3e-05 23.3 0.0 0.0018 18.4 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 PXF49978.1 - 0.027 14.2 0.0 0.078 12.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 PXF49978.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Apolipoprotein PF01442.18 PXF49978.1 - 0.88 9.4 5.8 0.54 10.1 0.1 2.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain tRNA-synt_1d PF00750.19 PXF49979.1 - 7.4e-120 400.0 0.0 1.4e-119 399.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 PXF49979.1 - 8e-25 87.3 0.0 1.9e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 PXF49979.1 - 1.3e-21 77.0 0.0 3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 PXF49979.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PXF49979.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF2985 PF11204.8 PXF49980.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) GFO_IDH_MocA PF01408.22 PXF49982.1 - 1.8e-19 70.7 0.0 3.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PXF49982.1 - 8.7e-09 35.4 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain EcsC PF12787.7 PXF49983.1 - 0.13 11.9 0.1 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 EcsC protein family DEAD PF00270.29 PXF49984.1 - 4e-46 157.0 0.0 8.2e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PXF49984.1 - 6.5e-26 90.8 0.0 3.4e-25 88.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PXF49984.1 - 1.3e-19 70.2 0.1 2.3e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PXF49984.1 - 2.6e-05 24.3 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 PXF49986.1 - 5.3e-05 23.3 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lipoprotein_3 PF00938.17 PXF49986.1 - 0.037 14.2 1.6 0.1 12.8 0.7 2.0 2 0 0 2 2 2 0 Lipoprotein RNB PF00773.19 PXF49987.1 - 5.4e-35 121.3 0.0 7.3e-29 101.1 0.0 2.5 2 0 0 2 2 2 2 RNB domain GTP_EFTU PF00009.27 PXF49989.1 - 3.7e-46 157.1 0.1 6.4e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PXF49989.1 - 4.6e-21 74.6 0.1 1e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PXF49989.1 - 2.8e-08 34.1 0.2 6.8e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PXF49989.1 - 3.5e-07 30.3 0.0 6.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 PXF49989.1 - 0.0053 16.8 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II Arf PF00025.21 PXF49989.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family UL42 PF17638.2 PXF49989.1 - 0.77 9.7 3.3 1.7 8.6 3.3 1.6 1 0 0 1 1 1 0 HCMV UL42 HLH PF00010.26 PXF49990.1 - 1.4e-05 24.9 1.0 2.8e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bHLH-MYC_N PF14215.6 PXF49990.1 - 6.8e-05 23.2 1.1 0.044 14.0 0.0 2.6 3 0 0 3 3 3 2 bHLH-MYC and R2R3-MYB transcription factors N-terminal Ras PF00071.22 PXF49991.1 - 1.8e-39 134.9 0.0 2.2e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PXF49991.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PXF49991.1 - 0.00033 20.3 0.0 0.00045 19.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RhoGAP PF00620.27 PXF49992.1 - 5.6e-15 55.5 0.0 9.1e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain NinF PF05810.12 PXF49992.1 - 0.036 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NinF protein Isochorismatase PF00857.20 PXF49993.1 - 3e-29 102.4 0.0 4.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Nucleotid_trans PF03407.16 PXF49994.1 - 6e-19 68.9 0.1 1.1e-18 68.0 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RSN1_7TM PF02714.15 PXF49995.1 - 1.5e-59 201.5 25.8 2.5e-59 200.8 25.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PXF49995.1 - 3.1e-30 105.0 0.5 3.1e-30 105.0 0.5 3.5 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PXF49995.1 - 7.4e-24 84.9 0.2 1.1e-23 84.4 0.2 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Tab2_like PF06485.11 PXF49996.1 - 7e-81 271.7 0.0 9.2e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 GST_N_3 PF13417.6 PXF49997.1 - 5.5e-13 49.1 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PXF49997.1 - 7.4e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PXF49997.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PXF49997.1 - 2.4e-08 34.2 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PXF49997.1 - 8.5e-05 23.2 0.1 0.00045 20.9 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 PXF49997.1 - 0.00014 22.0 0.1 0.00039 20.6 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 PXF49997.1 - 0.00042 20.5 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sen15 PF09631.10 PXF49999.1 - 1.7e-12 47.5 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Sen15 protein Med21 PF11221.8 PXF50000.1 - 3.4e-14 53.3 1.5 5.5e-14 52.6 1.5 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF1465 PF07323.12 PXF50000.1 - 0.021 14.7 0.9 0.042 13.7 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1465) Prefoldin_2 PF01920.20 PXF50001.1 - 1.4e-09 37.8 5.6 5.3e-09 36.0 1.2 2.1 1 1 1 2 2 2 1 Prefoldin subunit CC2-LZ PF16516.5 PXF50001.1 - 0.00062 20.1 3.6 0.00069 19.9 2.0 1.8 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4407 PF14362.6 PXF50001.1 - 0.011 15.2 5.8 0.018 14.4 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 PXF50001.1 - 0.26 11.7 9.5 0.27 11.7 2.5 2.8 2 1 0 2 2 2 0 Snapin/Pallidin DUF724 PF05266.14 PXF50001.1 - 0.52 10.1 8.0 3.7 7.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cauli_AT PF03233.13 PXF50001.1 - 0.56 10.1 6.1 5.2 7.0 0.2 2.0 1 1 1 2 2 2 0 Aphid transmission protein HR1 PF02185.16 PXF50001.1 - 2.2 8.5 12.3 0.049 13.7 2.4 2.1 2 0 0 2 2 2 0 Hr1 repeat Atg14 PF10186.9 PXF50001.1 - 2.4 7.2 8.8 5.8 5.9 8.8 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 PXF50001.1 - 2.9 8.4 14.0 5.6 7.5 1.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 PXF50001.1 - 3.1 7.8 12.1 22 5.1 12.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPT PF03151.16 PXF50002.1 - 8.1e-87 291.2 19.2 1e-86 290.9 19.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PXF50002.1 - 1.2e-10 41.7 29.7 4e-07 30.3 10.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family nsp7 PF08716.10 PXF50003.1 - 0.0041 17.7 0.0 1.1 9.9 0.0 2.8 2 0 0 2 2 2 2 nsp7 replicase BMFP PF04380.13 PXF50003.1 - 0.66 10.5 4.4 2.4 8.7 0.3 3.7 3 1 1 4 4 4 0 Membrane fusogenic activity DUF829 PF05705.14 PXF50004.1 - 6.5e-29 101.5 0.0 9.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_C14 PF00656.22 PXF50006.1 - 2.2e-45 155.5 0.0 4.3e-45 154.6 0.0 1.5 1 1 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 PXF50006.1 - 0.018 15.0 0.0 0.25 11.3 0.0 2.4 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Peptidase_C13 PF01650.18 PXF50006.1 - 0.025 14.1 1.1 4.9 6.6 0.1 2.4 1 1 0 2 2 2 0 Peptidase C13 family NAD_binding_10 PF13460.6 PXF50007.1 - 3.1e-34 118.5 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PXF50007.1 - 4.4e-06 26.4 0.0 2.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PXF50007.1 - 0.0004 19.9 0.0 0.0012 18.4 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 PXF50007.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 PXF50007.1 - 0.011 14.7 0.0 0.032 13.2 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SNF2_N PF00176.23 PXF50008.1 - 3.1e-66 223.5 0.5 7.4e-66 222.2 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF50008.1 - 2.8e-20 72.7 0.4 2.3e-19 69.8 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF50008.1 - 1.3e-07 31.8 0.0 4.5e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PXF50008.1 - 7.3e-07 28.6 0.0 2.9e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SKIP_SNW PF02731.15 PXF50009.1 - 6e-64 214.5 6.3 1e-63 213.8 6.3 1.4 1 0 0 1 1 1 1 SKIP/SNW domain Paf67 PF10255.9 PXF50010.1 - 3.7e-143 477.4 0.1 4.7e-143 477.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 PXF50010.1 - 0.0097 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 PXF50010.1 - 0.042 13.7 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PXF50010.1 - 0.81 10.5 2.7 1.5 9.6 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 PXF50012.1 - 4.7e-65 219.6 0.1 7e-65 219.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50012.1 - 4.3e-35 121.2 0.6 7.3e-35 120.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DEP PF00610.21 PXF50012.1 - 2.4e-20 72.4 0.1 5e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF547 PF04784.14 PXF50012.1 - 8.8e-11 41.9 0.0 2.2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Kinase-like PF14531.6 PXF50012.1 - 0.00015 21.2 0.0 0.00099 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PXF50012.1 - 0.00068 18.7 0.4 0.00068 18.7 0.4 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PXF50012.1 - 0.022 14.7 0.0 0.18 11.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PXF50012.1 - 0.032 13.8 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PXF50012.1 - 0.043 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CarD_CdnL_TRCF PF02559.16 PXF50012.1 - 0.17 12.6 0.2 0.44 11.3 0.2 1.8 1 0 0 1 1 1 0 CarD-like/TRCF domain DUF2267 PF10025.9 PXF50013.1 - 0.077 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) MMR_HSR1 PF01926.23 PXF50014.1 - 6.6e-42 142.2 0.0 1e-21 77.1 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PXF50014.1 - 1.3e-23 83.3 0.1 4e-12 45.9 0.0 4.3 3 1 0 4 4 4 3 Ferrous iron transport protein B GTP_EFTU PF00009.27 PXF50014.1 - 2.4e-18 66.4 0.5 2.1e-07 30.6 0.4 4.6 3 1 0 3 3 3 3 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PXF50014.1 - 3.3e-13 50.0 0.6 0.0055 16.8 0.1 4.4 4 0 0 4 4 4 3 Dynamin family KH_dom-like PF14714.6 PXF50014.1 - 3.4e-12 46.5 0.0 7.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal RsgA_GTPase PF03193.16 PXF50014.1 - 3.2e-11 43.4 0.8 0.0019 18.1 0.0 4.9 4 2 0 4 4 4 2 RsgA GTPase AIG1 PF04548.16 PXF50014.1 - 3.8e-11 42.7 0.0 3.1e-07 30.0 0.0 2.6 2 1 0 2 2 2 2 AIG1 family Roc PF08477.13 PXF50014.1 - 1.7e-08 34.7 0.1 0.58 10.4 0.0 4.3 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PXF50014.1 - 5.2e-08 32.6 0.1 0.035 13.7 0.0 4.3 4 0 0 4 4 4 1 Ras family AAA_22 PF13401.6 PXF50014.1 - 2.1e-06 28.0 0.5 0.074 13.3 0.2 3.9 2 2 0 2 2 2 2 AAA domain Septin PF00735.18 PXF50014.1 - 3.3e-05 23.3 0.0 0.0078 15.5 0.0 3.1 3 0 0 3 3 3 1 Septin ABC_tran PF00005.27 PXF50014.1 - 0.0001 22.8 0.0 0.15 12.6 0.1 2.7 2 1 0 2 2 2 1 ABC transporter MMR_HSR1_Xtn PF16897.5 PXF50014.1 - 0.00023 21.2 0.0 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain cobW PF02492.19 PXF50014.1 - 0.00077 19.1 5.4 0.5 9.9 0.2 4.2 4 1 1 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PXF50014.1 - 0.0021 18.5 5.1 0.88 9.9 0.1 3.6 3 1 0 3 3 2 1 AAA ATPase domain RNA_helicase PF00910.22 PXF50014.1 - 0.0021 18.4 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 PXF50014.1 - 0.0023 17.9 0.6 2.3 8.1 0.0 3.2 3 0 0 3 3 3 1 NTPase AAA_29 PF13555.6 PXF50014.1 - 0.0043 16.8 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain TniB PF05621.11 PXF50014.1 - 0.0044 16.4 0.0 4.6 6.6 0.0 3.1 2 1 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 PXF50014.1 - 0.0089 16.0 0.0 1.8 8.5 0.0 3.4 3 1 0 3 3 3 1 NACHT domain AAA_25 PF13481.6 PXF50014.1 - 0.012 15.2 5.1 0.37 10.3 0.0 3.7 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 PXF50014.1 - 0.014 14.4 0.3 9.5 5.1 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 PXF50014.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 PXF50014.1 - 0.019 15.5 0.0 12 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 PXF50014.1 - 0.031 14.7 0.0 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PXF50014.1 - 0.043 13.0 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 PXF50014.1 - 0.049 13.5 0.1 4.7 7.1 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 PXF50014.1 - 0.062 13.5 1.5 7.1 6.8 0.1 3.4 3 2 0 3 3 3 0 AAA domain SRPRB PF09439.10 PXF50014.1 - 0.071 12.5 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 PXF50014.1 - 0.076 12.9 0.0 6.9 6.5 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea GBP PF02263.19 PXF50014.1 - 0.083 12.1 0.0 0.67 9.2 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 PXF50014.1 - 0.099 12.9 0.1 15 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 PXF50014.1 - 0.15 11.5 0.4 44 3.5 0.0 3.7 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_24 PF13479.6 PXF50014.1 - 0.23 11.2 0.1 31 4.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Nuc_deoxyri_tr2 PF15891.5 PXF50014.1 - 1 9.7 4.4 1.1 9.6 0.2 3.0 4 0 0 4 4 3 0 Nucleoside 2-deoxyribosyltransferase like E2F_CC-MB PF16421.5 PXF50015.1 - 2.9e-29 101.3 0.0 4.7e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 PXF50015.1 - 8.6e-25 86.6 0.2 1.5e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain CLZ PF16526.5 PXF50015.1 - 0.0058 17.0 2.4 0.48 10.8 0.1 2.4 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 PXF50015.1 - 0.0066 16.4 0.4 0.015 15.3 0.4 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 PXF50015.1 - 0.022 15.3 0.5 0.037 14.5 0.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 PXF50015.1 - 0.039 14.4 0.2 0.28 11.6 0.3 2.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF4140 PF13600.6 PXF50015.1 - 0.043 14.3 3.0 0.096 13.1 3.0 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.6 PXF50015.1 - 0.049 13.9 2.9 0.094 13.0 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DivIC PF04977.15 PXF50015.1 - 0.052 13.3 1.1 0.092 12.5 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Nup54 PF13874.6 PXF50015.1 - 0.087 12.9 0.7 0.14 12.2 0.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TrmB PF01978.19 PXF50015.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4407 PF14362.6 PXF50015.1 - 0.16 11.3 1.4 0.29 10.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT PF02985.22 PXF50016.1 - 1.4e-25 87.1 63.4 0.015 15.5 0.3 24.4 29 0 0 29 29 28 10 HEAT repeat HEAT_EZ PF13513.6 PXF50016.1 - 2.8e-22 78.8 63.3 0.00052 20.5 0.6 20.5 19 3 3 22 22 21 8 HEAT-like repeat HEAT_2 PF13646.6 PXF50016.1 - 4e-19 68.8 56.8 0.0064 16.9 1.8 18.3 16 6 3 19 19 19 5 HEAT repeats Vac14_Fab1_bd PF12755.7 PXF50016.1 - 1.5e-15 57.5 0.0 0.24 12.0 0.0 10.0 6 3 3 9 9 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PXF50016.1 - 5.5e-11 42.5 0.4 0.069 12.7 0.0 8.2 6 2 3 9 9 9 3 CLASP N terminal Cnd1 PF12717.7 PXF50016.1 - 2.5e-09 37.4 10.3 2.6 8.1 0.0 11.1 10 2 1 12 12 12 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 PXF50016.1 - 0.0017 18.5 0.0 0.44 10.6 0.0 4.4 3 1 0 3 3 3 1 Parkin co-regulated protein Adaptin_N PF01602.20 PXF50016.1 - 0.0027 16.4 7.6 26 3.2 0.1 7.3 7 1 0 7 7 7 0 Adaptin N terminal region TIP120 PF08623.10 PXF50016.1 - 0.0076 16.0 0.0 3.3 7.5 0.0 4.7 7 0 0 7 7 7 1 TATA-binding protein interacting (TIP20) Mur_ligase_M PF08245.12 PXF50016.1 - 0.021 14.8 0.8 0.047 13.7 0.8 1.5 1 0 0 1 1 1 0 Mur ligase middle domain Fib_alpha PF08702.10 PXF50016.1 - 0.13 12.4 1.2 0.35 11.0 0.4 2.2 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Myb_DNA-binding PF00249.31 PXF50017.1 - 4.4e-08 33.2 0.0 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PXF50017.1 - 5.9e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3245 PF11595.8 PXF50017.1 - 0.029 14.8 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Myb_DNA-bind_5 PF13873.6 PXF50017.1 - 0.07 13.2 2.5 0.4 10.8 1.8 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 PXF50017.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 SLIDE GHMP_kinases_N PF00288.26 PXF50017.1 - 0.27 11.5 2.9 0.53 10.6 2.9 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain Fzo_mitofusin PF04799.13 PXF50018.1 - 0.011 15.3 2.1 0.011 15.3 2.1 4.7 3 1 1 4 4 4 0 fzo-like conserved region NPV_P10 PF05531.12 PXF50018.1 - 0.15 12.5 3.1 1.4 9.4 0.9 3.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Img2 PF05046.14 PXF50018.1 - 0.63 10.4 3.6 5 7.5 0.1 3.1 2 1 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Pkinase PF00069.25 PXF50019.1 - 3.3e-70 236.5 0.0 3.7e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50019.1 - 1.2e-31 110.0 0.0 6e-31 107.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PXF50019.1 - 9.2e-07 28.5 0.0 5.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PXF50019.1 - 0.00058 19.9 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 PXF50019.1 - 0.012 15.3 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PXF50019.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PXF50019.1 - 0.08 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RHD3 PF05879.12 PXF50021.1 - 6.9e-63 213.0 6.3 1.4e-62 211.9 6.3 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 PXF50021.1 - 7e-06 26.1 0.1 2.7e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PXF50021.1 - 0.0011 19.1 3.7 0.0013 18.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 PXF50021.1 - 0.0053 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GBP PF02263.19 PXF50021.1 - 0.007 15.7 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Roc PF08477.13 PXF50021.1 - 0.079 13.2 0.7 0.45 10.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PXF50021.1 - 0.4 11.2 5.6 2.3 8.8 0.1 3.4 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 PXF50021.1 - 2.3 8.5 5.1 0.4 10.9 0.2 2.3 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PXF50021.1 - 2.6 8.4 6.9 0.38 11.1 0.7 2.7 2 2 0 2 2 2 0 AAA ATPase domain SecE PF00584.20 PXF50022.1 - 6.8e-10 38.7 1.5 8.9e-10 38.4 1.5 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex EamA PF00892.20 PXF50023.1 - 1.6e-08 34.8 11.8 2.4e-05 24.5 4.1 3.1 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 PXF50023.1 - 2.7e-07 30.1 0.3 3.8e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 PXF50023.1 - 2.2e-05 23.6 0.3 3.7e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 PXF50023.1 - 0.0005 19.5 0.2 0.00076 18.9 0.2 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.6 PXF50023.1 - 0.0065 16.1 0.4 0.0093 15.6 0.4 1.3 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter UAA PF08449.11 PXF50023.1 - 0.0076 15.5 0.2 0.0076 15.5 0.2 2.6 2 1 0 3 3 3 1 UAA transporter family DUF4133 PF13571.6 PXF50023.1 - 1 9.7 10.2 4.5 7.7 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) DnaJ PF00226.31 PXF50024.1 - 3.4e-22 78.3 0.1 6.3e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain XAP5 PF04921.14 PXF50025.1 - 6.3e-77 258.8 2.8 6.3e-77 258.8 2.8 1.7 2 0 0 2 2 2 1 XAP5, circadian clock regulator DASH_Spc19 PF08287.11 PXF50025.1 - 7.7 6.4 10.7 0.38 10.6 3.6 2.2 2 0 0 2 2 2 0 Spc19 Peptidase_M17 PF00883.21 PXF50026.1 - 2.3e-97 326.1 0.0 2.8e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Tocopherol_cycl PF14249.6 PXF50027.1 - 1.1e-90 304.3 5.0 1.2e-90 304.0 5.0 1.0 1 0 0 1 1 1 1 Tocopherol cyclase Cyclin_N PF00134.23 PXF50028.1 - 6.2e-14 51.8 0.7 5.8e-13 48.7 0.7 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain SKA2 PF16740.5 PXF50029.1 - 2.1e-06 27.5 0.7 4.5e-06 26.4 0.7 1.7 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Selenoprotein_S PF06936.11 PXF50029.1 - 0.4 10.5 1.7 9.3 6.0 0.3 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) VASt PF16016.5 PXF50030.1 - 9.2e-24 84.6 0.0 1.8e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 PXF50030.1 - 4.2e-14 52.4 0.1 8.2e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 GRAM domain PH_BEACH PF14844.6 PXF50030.1 - 0.053 13.6 0.0 1.3 9.1 0.0 2.9 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH Ribosomal_S19 PF00203.21 PXF50031.1 - 1.1e-19 70.1 0.0 3.9e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S19 Peptidase_C48 PF02902.19 PXF50032.1 - 3.4e-26 92.4 0.0 1.8e-25 90.0 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KA1 PF02149.19 PXF50032.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 Plant_tran PF04827.14 PXF50034.1 - 3.1e-22 79.2 0.3 4e-22 78.8 0.3 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 PXF50034.1 - 1.5e-06 28.0 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 PXF50034.1 - 0.07 13.5 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain WAC_Acf1_DNA_bd PF10537.9 PXF50035.1 - 0.0091 16.5 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal NAM-associated PF14303.6 PXF50035.1 - 0.32 11.7 8.6 0.1 13.3 5.6 1.6 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain WD40 PF00400.32 PXF50038.1 - 0.00012 22.8 0.6 0.00048 20.9 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Ank_4 PF13637.6 PXF50039.1 - 3.6e-09 37.0 0.0 5.4e-05 23.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PXF50039.1 - 7.7e-06 26.1 0.0 0.00037 20.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PXF50039.1 - 7.2e-05 22.9 0.0 0.0067 16.9 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PXF50039.1 - 0.00018 22.0 0.0 0.013 16.0 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 PXF50039.1 - 0.0024 18.2 0.1 0.04 14.4 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeat CRAM_rpt PF07016.11 PXF50040.1 - 0.31 10.9 2.4 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor N6_N4_Mtase PF01555.18 PXF50041.1 - 4.1e-06 26.7 0.0 6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 DNA methylase DUF3310 PF11753.8 PXF50041.1 - 0.15 12.2 0.0 8.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) Pro_isomerase PF00160.21 PXF50042.1 - 2.1e-37 128.9 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyrosinase PF00264.20 PXF50043.1 - 9.9e-35 120.8 3.8 1.2e-32 114.1 3.8 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase FAP PF07174.11 PXF50043.1 - 0.072 12.5 13.6 0.15 11.5 13.6 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DEC-1_N PF04625.13 PXF50043.1 - 0.34 9.9 11.9 0.5 9.3 11.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Neisseria_TspB PF05616.13 PXF50043.1 - 0.87 8.0 5.1 1.6 7.1 5.1 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Glyco_hydro_63 PF03200.16 PXF50044.1 - 5.9e-14 51.7 6.6 3e-09 36.2 0.0 3.8 2 2 1 3 3 3 3 Glycosyl hydrolase family 63 C-terminal domain Trehalase PF01204.18 PXF50044.1 - 1.1e-09 37.8 0.0 1.6e-09 37.1 0.0 1.4 1 1 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 PXF50044.1 - 0.0041 16.4 0.1 0.0095 15.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF716 PF04819.12 PXF50044.1 - 0.08 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF716) G-patch PF01585.23 PXF50045.1 - 1.8e-05 24.5 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 G-patch domain ABC_membrane_2 PF06472.15 PXF50046.1 - 7.4e-55 186.2 6.4 1e-54 185.7 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PXF50046.1 - 2.3e-20 73.5 0.0 5.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 PXF50046.1 - 9.6e-11 41.7 6.9 6.8e-10 38.9 6.9 2.0 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_30 PF13604.6 PXF50046.1 - 0.0007 19.4 0.1 0.013 15.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 PXF50046.1 - 0.00087 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 PXF50046.1 - 0.0025 17.3 0.8 1.9 7.9 0.1 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PXF50046.1 - 0.0043 17.0 0.1 0.0095 15.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 PXF50046.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 PXF50046.1 - 0.0084 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 PXF50046.1 - 0.015 14.9 9.2 0.037 13.7 9.2 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_16 PF13191.6 PXF50046.1 - 0.017 15.5 0.2 0.042 14.2 0.2 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 PXF50046.1 - 0.041 13.7 0.1 0.4 10.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 PXF50046.1 - 0.099 12.9 0.3 0.26 11.5 0.1 1.8 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 PXF50046.1 - 0.11 12.9 0.2 1.6 9.2 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PXF50046.1 - 0.11 13.0 0.0 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PXF50046.1 - 0.13 12.0 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 PXF50046.1 - 0.21 11.1 0.4 4.8 6.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain XG_FTase PF03254.13 PXF50047.1 - 0.00057 18.6 0.0 0.81 8.2 0.0 3.1 3 0 0 3 3 3 3 Xyloglucan fucosyltransferase Orbi_VP7 PF00897.17 PXF50047.1 - 0.0042 16.1 0.3 0.0076 15.3 0.3 1.4 1 0 0 1 1 1 1 Orbivirus inner capsid protein VP7 NodZ PF05830.11 PXF50047.1 - 0.0046 15.8 0.0 0.21 10.4 0.0 2.4 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) Nucleotid_trans PF03407.16 PXF50048.1 - 4.1e-34 118.4 0.0 4.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Epimerase PF01370.21 PXF50049.1 - 8.4e-14 51.6 0.1 1.4e-11 44.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PXF50049.1 - 2e-13 50.4 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 PXF50049.1 - 2.9e-12 46.2 0.0 8.3e-09 34.8 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PXF50049.1 - 8.5e-10 38.8 0.0 1.8e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PXF50049.1 - 1.4e-07 30.9 0.0 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 PXF50049.1 - 0.0002 20.7 1.3 0.19 10.8 0.2 3.0 1 1 2 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 PXF50049.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Branch PF02485.21 PXF50050.1 - 8.8e-31 107.3 1.3 1.4e-30 106.6 1.3 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme QueC PF06508.13 PXF50050.1 - 0.19 11.2 0.1 0.36 10.3 0.1 1.4 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC polyprenyl_synt PF00348.17 PXF50051.1 - 2.9e-82 275.6 0.1 3.5e-82 275.3 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Uma2 PF05685.12 PXF50052.1 - 1.7e-25 89.6 0.0 2.2e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Sigma70_r2 PF04542.14 PXF50053.1 - 1.4e-10 40.8 0.0 3.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PXF50053.1 - 0.00034 20.1 2.9 0.0023 17.4 1.3 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 PXF50053.1 - 0.93 9.2 4.1 1.7 8.4 0.7 3.0 2 1 0 2 2 2 0 Sigma-70, region 4 AAA_12 PF13087.6 PXF50054.1 - 4.2e-29 101.6 0.0 1.6e-28 99.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PXF50054.1 - 5e-14 52.7 8.8 1.1e-06 28.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain zf-CCCH PF00642.24 PXF50054.1 - 1.5e-12 47.1 14.6 3.7e-07 29.9 1.0 4.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PXF50054.1 - 2.3e-08 33.6 21.7 5.6e-06 26.0 2.4 4.5 4 0 0 4 4 4 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PXF50054.1 - 8.1e-08 32.1 26.6 0.00022 21.1 6.4 3.7 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 PXF50054.1 - 0.0018 18.9 10.4 0.17 12.6 4.2 3.1 1 1 1 2 2 2 2 Torus domain AAA_30 PF13604.6 PXF50054.1 - 0.0019 17.9 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PXF50054.1 - 0.081 12.2 0.1 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PXF50054.1 - 0.11 12.9 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-CCCH_2 PF14608.6 PXF50054.1 - 4.7 7.8 16.0 3.9 8.1 1.3 4.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Oxidored_molyb PF00174.19 PXF50055.1 - 3e-58 196.2 0.0 5.5e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PXF50055.1 - 1.8e-42 144.6 0.0 3.3e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 PXF50055.1 - 1.1e-31 109.1 0.0 3.4e-31 107.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PXF50055.1 - 3.3e-31 108.1 0.0 9.1e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 PXF50055.1 - 7.5e-23 80.5 0.1 1.5e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 PXF50055.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Big_7 PF17957.1 PXF50055.1 - 0.029 15.2 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig domain BNR PF02012.20 PXF50055.1 - 0.084 12.9 1.0 0.43 10.8 0.0 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Synaptobrevin PF00957.21 PXF50056.1 - 2.3e-22 78.6 4.5 3.7e-22 77.9 4.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PXF50056.1 - 2.8e-12 46.5 0.2 5.3e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SNARE PF05739.19 PXF50056.1 - 0.0046 16.9 0.7 0.0046 16.9 0.7 2.4 2 1 0 2 2 2 1 SNARE domain DUF4239 PF14023.6 PXF50056.1 - 0.0067 16.2 0.8 0.014 15.1 0.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4239) Fzo_mitofusin PF04799.13 PXF50056.1 - 0.013 15.1 2.1 0.023 14.3 2.1 1.5 1 1 0 1 1 1 0 fzo-like conserved region Insulin_TMD PF17870.1 PXF50056.1 - 0.021 14.9 0.9 0.045 13.8 0.9 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Jnk-SapK_ap_N PF09744.9 PXF50056.1 - 0.1 12.8 2.1 0.17 12.1 2.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prominin PF05478.11 PXF50056.1 - 0.29 9.0 5.9 0.066 11.2 2.5 1.5 1 1 1 2 2 2 0 Prominin 2OG-FeII_Oxy_5 PF13759.6 PXF50059.1 - 4.7e-15 55.8 0.3 1.5e-13 51.0 0.3 2.4 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 PXF50059.1 - 1.7e-05 25.6 0.0 3.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 PXF50059.1 - 0.11 12.3 0.5 0.47 10.2 0.5 2.1 1 1 0 1 1 1 0 Cupin domain Sulf_transp PF04143.14 PXF50060.1 - 4.8e-08 32.9 26.2 7.2e-08 32.3 9.3 3.3 3 1 0 3 3 3 2 Sulphur transport CBS PF00571.28 PXF50061.1 - 3.6e-28 97.8 9.9 3.8e-07 30.4 0.1 5.4 5 0 0 5 5 5 4 CBS domain TPR_1 PF00515.28 PXF50061.1 - 3e-17 61.6 12.7 7.4e-06 25.6 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat PB1 PF00564.24 PXF50061.1 - 7.8e-13 48.2 0.1 3.1e-12 46.2 0.1 2.1 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.6 PXF50061.1 - 3.6e-12 45.8 15.6 4.6e-05 23.0 0.0 5.2 5 1 1 6 6 5 4 TPR repeat TPR_2 PF07719.17 PXF50061.1 - 2.5e-11 42.8 20.4 0.0027 17.7 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 PXF50061.1 - 3.2e-11 43.6 7.6 0.0025 18.3 0.7 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 PXF50061.1 - 9.6e-10 39.0 14.8 0.00026 21.6 0.1 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PXF50061.1 - 1.9e-06 27.7 13.8 0.065 13.5 0.2 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PXF50061.1 - 1.4e-05 24.7 7.8 0.0058 16.6 0.3 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PXF50061.1 - 1.6e-05 25.0 1.9 0.011 15.9 1.4 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PXF50061.1 - 0.0002 21.9 17.0 0.024 15.5 1.5 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PXF50061.1 - 0.00022 21.4 17.9 0.015 15.6 1.1 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF50061.1 - 0.0021 18.6 9.6 1.2 9.9 0.1 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF50061.1 - 0.0025 17.9 1.3 0.019 15.1 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PXF50061.1 - 0.0044 17.3 0.2 3.7 8.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PXF50061.1 - 0.068 13.1 8.9 1.5 8.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 PXF50061.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 PXF50061.1 - 3.6 7.6 5.1 96 3.0 0.1 4.1 2 2 2 4 4 4 0 Domain of Unknown Function (DUF3856) NRBF2_MIT PF17169.4 PXF50061.1 - 6.8 7.0 5.8 4.8 7.5 0.1 3.2 4 0 0 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 BTAD PF03704.17 PXF50061.1 - 7.2 7.0 9.6 18 5.7 0.5 2.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Glyco_transf_90 PF05686.12 PXF50062.1 - 5.4e-29 101.3 0.1 1.5e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 ACPS PF01648.20 PXF50063.1 - 8.7e-16 58.1 0.1 4.1e-15 55.9 0.0 2.0 2 1 1 3 3 3 1 4'-phosphopantetheinyl transferase superfamily SNF2_N PF00176.23 PXF50064.1 - 3.4e-72 243.1 2.3 5e-72 242.5 1.5 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PXF50064.1 - 3.2e-21 75.7 0.0 5.8e-20 71.7 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PXF50064.1 - 5.6e-08 33.0 0.4 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SnAC PF14619.6 PXF50064.1 - 7.3e-07 29.7 1.1 7.3e-07 29.7 1.1 3.7 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HDA2-3 PF11496.8 PXF50064.1 - 1.9e-05 24.0 0.0 5.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 PXF50064.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNRNP27 PF08648.12 PXF50064.1 - 0.025 14.6 0.0 6.6 6.9 0.0 2.9 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins DUF3843 PF12954.7 PXF50064.1 - 7.2 5.5 8.6 0.25 10.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3843) Acetyltransf_CG PF14542.6 PXF50065.1 - 1.5e-26 92.3 0.1 1.7e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 PXF50065.1 - 1.7e-05 25.1 0.0 2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PXF50065.1 - 0.0021 18.0 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PXF50065.1 - 0.0035 17.7 0.0 0.0041 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_2 PF02230.16 PXF50067.1 - 2.7e-38 131.9 0.0 1.3e-36 126.4 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PXF50067.1 - 5e-07 29.4 0.1 0.00011 21.7 0.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PXF50067.1 - 1.8e-06 27.4 0.0 0.0031 16.8 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF50067.1 - 5.3e-06 26.3 0.1 0.00027 20.7 0.0 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PXF50067.1 - 9.1e-06 26.4 0.7 3.3e-05 24.6 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 PXF50067.1 - 3e-05 23.8 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 PXF50067.1 - 0.00045 20.1 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 PXF50067.1 - 0.0062 15.3 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 PXF50067.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 PXF50067.1 - 0.043 13.9 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PE-PPE PF08237.11 PXF50067.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Peptidase_M41 PF01434.18 PXF50068.1 - 8e-62 208.5 2.4 1.7e-61 207.4 2.4 1.5 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PXF50068.1 - 6.5e-41 139.9 0.0 1.4e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PXF50068.1 - 4.3e-10 39.2 0.1 9.7e-10 38.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PXF50068.1 - 0.00069 19.6 0.0 0.0029 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PXF50068.1 - 0.0022 18.4 1.9 0.26 11.6 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PXF50068.1 - 0.0076 16.5 0.4 0.5 10.6 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 PXF50068.1 - 0.012 15.3 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PXF50068.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PXF50068.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 PXF50068.1 - 0.085 13.0 0.0 0.41 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain Pox_P35 PF03213.14 PXF50068.1 - 0.21 10.8 0.1 0.32 10.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein TMF_DNA_bd PF12329.8 PXF50070.1 - 4.2e-06 26.6 16.7 0.0019 18.2 0.2 3.2 3 0 0 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 PXF50070.1 - 0.00021 20.7 10.8 0.09 12.1 6.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) DASH_Dam1 PF08653.10 PXF50070.1 - 0.00046 19.9 0.4 0.096 12.5 0.0 2.6 2 1 1 3 3 3 1 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.9 PXF50070.1 - 0.0021 18.1 5.1 0.0021 18.1 5.1 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 PXF50070.1 - 0.0032 18.0 16.7 0.074 13.6 11.9 2.2 1 1 1 2 2 2 1 Apg6 coiled-coil region DUF812 PF05667.11 PXF50070.1 - 0.0035 16.3 11.6 0.0042 16.1 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) KASH_CCD PF14662.6 PXF50070.1 - 0.0044 16.9 16.7 0.064 13.1 16.5 2.2 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 PXF50070.1 - 0.0055 16.6 4.4 0.0055 16.6 4.4 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family NPV_P10 PF05531.12 PXF50070.1 - 0.0058 17.1 1.5 0.15 12.6 1.1 2.5 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PXF50070.1 - 0.0083 16.2 7.4 0.12 12.4 3.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 PXF50070.1 - 0.012 15.8 19.1 0.074 13.3 2.0 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 PXF50070.1 - 0.022 14.2 7.2 0.027 13.8 7.2 1.0 1 0 0 1 1 1 0 FAM76 protein BLOC1_2 PF10046.9 PXF50070.1 - 0.025 14.9 7.2 0.58 10.5 3.9 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 PXF50070.1 - 0.027 15.2 5.1 1.5 9.6 1.9 2.3 2 1 0 2 2 2 0 Occludin homology domain Exonuc_VII_L PF02601.15 PXF50070.1 - 0.03 13.9 6.2 0.036 13.6 6.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 PXF50070.1 - 0.033 14.6 11.8 1.2 9.6 0.5 3.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 PXF50070.1 - 0.037 14.1 17.9 0.23 11.6 1.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4192 PF13830.6 PXF50070.1 - 0.042 13.9 7.1 0.046 13.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF948 PF06103.11 PXF50070.1 - 0.045 14.0 0.7 0.15 12.4 0.2 2.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 PXF50070.1 - 0.049 13.0 18.5 0.23 10.8 1.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2730 PF10805.8 PXF50070.1 - 0.058 13.5 3.1 0.077 13.1 0.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Jnk-SapK_ap_N PF09744.9 PXF50070.1 - 0.06 13.6 21.5 2.1 8.6 2.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 PXF50070.1 - 0.064 13.5 12.4 0.46 10.8 0.2 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF496 PF04363.12 PXF50070.1 - 0.066 13.2 0.5 0.066 13.2 0.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF496) ATG16 PF08614.11 PXF50070.1 - 0.066 13.4 19.8 0.33 11.1 19.7 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 PXF50070.1 - 0.068 13.3 11.1 0.11 12.6 10.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 PXF50070.1 - 0.076 11.6 11.3 0.29 9.7 11.3 1.7 1 1 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.7 PXF50070.1 - 0.088 13.0 19.2 0.41 10.8 7.0 3.0 1 1 1 2 2 2 0 Tropomyosin like Tropomyosin PF00261.20 PXF50070.1 - 0.1 12.0 21.6 0.48 9.8 21.6 1.8 1 1 0 1 1 1 0 Tropomyosin DivIC PF04977.15 PXF50070.1 - 0.13 12.0 17.2 0.97 9.3 0.3 4.1 1 1 4 5 5 5 0 Septum formation initiator Rootletin PF15035.6 PXF50070.1 - 0.13 12.2 16.2 1.4 8.9 13.4 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GCN5L1 PF06320.13 PXF50070.1 - 0.24 11.6 14.0 3.8 7.7 11.1 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) ZapB PF06005.12 PXF50070.1 - 0.25 11.8 0.2 0.25 11.8 0.2 3.9 2 1 2 4 4 3 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 PXF50070.1 - 0.25 11.4 22.2 0.59 10.2 2.4 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 PXF50070.1 - 0.33 11.4 16.7 1.2 9.5 15.8 2.0 1 1 0 1 1 1 0 Fez1 HemX PF04375.14 PXF50070.1 - 0.34 10.2 9.8 1.6 7.9 8.4 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MbeD_MobD PF04899.12 PXF50070.1 - 0.34 11.0 10.8 6.9 6.9 0.2 3.8 2 2 2 4 4 3 0 MbeD/MobD like BRI3BP PF14965.6 PXF50070.1 - 0.35 10.4 11.4 0.18 11.3 0.5 3.7 2 1 2 4 4 4 0 Negative regulator of p53/TP53 FlaC_arch PF05377.11 PXF50070.1 - 0.37 11.2 10.9 0.4 11.1 0.4 3.2 5 0 0 5 5 2 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 PXF50070.1 - 0.4 11.1 14.5 37 4.7 14.2 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3287 PF11690.8 PXF50070.1 - 0.4 10.4 3.7 4.1 7.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Spc7 PF08317.11 PXF50070.1 - 0.48 9.3 16.9 1.4 7.7 16.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 PXF50070.1 - 0.5 10.4 8.7 2.1 8.4 3.6 2.3 1 1 1 2 2 2 0 Laminin Domain II Ax_dynein_light PF10211.9 PXF50070.1 - 0.53 10.2 17.6 1.3 8.9 5.1 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain Lectin_N PF03954.14 PXF50070.1 - 0.62 9.8 5.6 6.9 6.4 2.4 3.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain YabA PF06156.13 PXF50070.1 - 0.72 10.5 12.4 2.7 8.7 0.2 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 PXF50070.1 - 0.81 9.9 6.8 0.62 10.3 3.3 2.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PLAC9 PF15205.6 PXF50070.1 - 0.89 10.0 3.1 0.75 10.2 0.4 2.2 1 1 1 2 2 2 0 Placenta-specific protein 9 Lebercilin PF15619.6 PXF50070.1 - 0.91 9.2 20.2 35 4.0 20.0 2.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_TACC PF12709.7 PXF50070.1 - 1.3 9.6 9.8 5.7 7.5 0.5 3.7 1 1 4 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 PXF50070.1 - 1.3 8.3 10.1 1.8 7.8 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 PXF50070.1 - 1.4 9.1 22.6 0.28 11.3 0.4 3.8 2 1 1 3 3 2 0 bZIP transcription factor BST2 PF16716.5 PXF50070.1 - 1.5 9.5 14.2 1.3 9.6 4.7 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF4472 PF14739.6 PXF50070.1 - 2 9.2 15.5 3.9 8.3 11.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) CENP-H PF05837.12 PXF50070.1 - 2 8.8 20.5 4.4 7.8 0.3 3.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF16 PF01519.16 PXF50070.1 - 2.3 8.8 11.5 1.2 9.6 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF4618 PF15397.6 PXF50070.1 - 2.4 7.5 11.9 0.22 10.9 2.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Macoilin PF09726.9 PXF50070.1 - 2.8 6.4 17.3 0.59 8.6 13.1 1.7 1 1 1 2 2 2 0 Macoilin family Paralemmin PF03285.15 PXF50070.1 - 3.1 7.3 13.5 0.042 13.4 1.4 2.4 1 1 1 2 2 2 0 Paralemmin BRE1 PF08647.11 PXF50070.1 - 3.3 7.9 15.6 7 6.8 0.6 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4337 PF14235.6 PXF50070.1 - 3.5 7.7 13.1 70 3.5 11.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF641 PF04859.12 PXF50070.1 - 3.7 7.9 12.3 1.9e+02 2.4 11.2 2.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TSC22 PF01166.18 PXF50070.1 - 3.8 7.9 11.8 4.7 7.6 0.3 3.9 2 1 1 4 4 4 0 TSC-22/dip/bun family DMPK_coil PF08826.10 PXF50070.1 - 3.8 7.7 17.0 2.2 8.4 0.6 3.8 2 1 2 4 4 4 0 DMPK coiled coil domain like TRAF_BIRC3_bd PF16673.5 PXF50070.1 - 4.7 7.1 14.8 0.15 11.8 1.6 3.5 2 2 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Wtap PF17098.5 PXF50070.1 - 5.1 7.0 13.6 22 4.9 9.2 2.9 1 1 1 2 2 2 0 WTAP/Mum2p family V_ATPase_I PF01496.19 PXF50070.1 - 5.6 4.7 7.8 7.2 4.4 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JIP_LZII PF16471.5 PXF50070.1 - 6.1 7.1 14.9 2.4 8.4 0.3 3.3 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II WD40_alt PF14077.6 PXF50070.1 - 6.9 6.6 8.7 13 5.8 0.6 3.4 2 1 1 3 3 3 0 Alternative WD40 repeat motif Cupin_8 PF13621.6 PXF50071.1 - 2e-16 60.5 0.0 3.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain NTP_transf_2 PF01909.23 PXF50071.1 - 2.5e-06 27.7 0.0 5.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 PXF50071.1 - 0.00044 20.3 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Cupin_4 PF08007.12 PXF50071.1 - 0.0017 17.9 0.0 0.0049 16.4 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 PXF50071.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Cupin MdcG PF10620.9 PXF50071.1 - 0.04 13.7 0.1 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG UDG PF03167.19 PXF50072.1 - 2e-05 24.6 0.0 3.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Guanylate_kin PF00625.21 PXF50073.1 - 1.5e-52 177.9 0.0 2.5e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 PXF50073.1 - 3.9e-05 24.1 0.1 0.00035 21.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PXF50073.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PXF50073.1 - 0.0041 17.2 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PXF50073.1 - 0.0052 16.2 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 PXF50073.1 - 0.0055 16.9 0.2 0.039 14.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 PXF50073.1 - 0.0071 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 PXF50073.1 - 0.011 16.1 0.0 0.051 14.0 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PXF50073.1 - 0.02 15.2 0.0 0.053 13.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 PXF50073.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PXF50073.1 - 0.029 14.6 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PXF50073.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 PXF50073.1 - 0.048 14.2 0.0 0.58 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 PXF50073.1 - 0.062 12.5 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 PXF50073.1 - 0.073 13.1 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 PXF50073.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 PXF50073.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 PXF50073.1 - 0.18 11.5 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Nup88 PF10168.9 PXF50074.1 - 2.3e-06 25.7 0.0 2.3e-06 25.7 0.0 2.7 2 1 0 3 3 3 1 Nuclear pore component Sipho_Gp157 PF05565.11 PXF50074.1 - 0.2 11.7 5.7 0.12 12.4 2.9 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 Cytochrom_B562 PF07361.11 PXF50074.1 - 0.2 12.4 2.2 0.63 10.7 2.2 1.8 1 0 0 1 1 1 0 Cytochrome b562 DUF1664 PF07889.12 PXF50074.1 - 0.24 11.5 2.0 0.24 11.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 PXF50074.1 - 0.25 10.2 14.3 0.028 13.3 8.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein FlaF PF07309.11 PXF50074.1 - 1.5 8.9 8.4 0.51 10.4 0.5 2.8 2 1 0 2 2 2 0 Flagellar protein FlaF DHR10 PF18595.1 PXF50074.1 - 9.1 6.4 18.9 0.64 10.1 13.0 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HEAT PF02985.22 PXF50075.1 - 0.017 15.3 0.0 1.1 9.7 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat MRC1 PF09444.10 PXF50076.1 - 5.2 7.6 5.9 6.3 7.3 1.2 2.4 2 1 1 3 3 3 0 MRC1-like domain ABC2_membrane_3 PF12698.7 PXF50077.1 - 0.17 10.9 0.8 0.2 10.7 0.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein IP_trans PF02121.18 PXF50078.1 - 3.8e-62 210.1 0.1 4.6e-62 209.8 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Cofilin_ADF PF00241.20 PXF50079.1 - 1.3e-23 83.1 0.4 1.4e-23 83.0 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HEPN-like_int PF18867.1 PXF50079.1 - 0.054 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 HEPN-like integron domain PAP_fibrillin PF04755.12 PXF50080.1 - 4e-08 33.5 0.0 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 2 PAP_fibrillin Ribosomal_S19e PF01090.19 PXF50081.1 - 3.5e-52 175.8 0.0 4.2e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.10 PXF50081.1 - 0.0018 18.2 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HrcA_DNA-bdg PF03444.15 PXF50081.1 - 0.018 14.7 0.1 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Mrr_N PF14338.6 PXF50081.1 - 0.068 13.3 0.2 0.27 11.4 0.1 1.8 2 0 0 2 2 2 0 Mrr N-terminal domain V_ATPase_prox PF18274.1 PXF50081.1 - 0.1 12.6 0.0 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe YppF PF14178.6 PXF50081.1 - 0.19 11.6 0.3 0.93 9.4 0.1 2.0 2 0 0 2 2 2 0 YppF-like protein Pkinase PF00069.25 PXF50082.1 - 7.1e-64 215.7 0.0 8.7e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50082.1 - 6.5e-41 140.3 0.0 1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PXF50082.1 - 0.0051 16.2 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SgrR_N PF12793.7 PXF50082.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term A_thal_3526 PF09713.10 PXF50083.1 - 0.022 15.0 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) BPD_transp_1 PF00528.22 PXF50084.1 - 2.9e-24 85.8 38.2 1.4e-15 57.5 12.1 3.2 3 1 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component DUF373 PF04123.13 PXF50084.1 - 9.2 5.6 12.4 0.37 10.2 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Hydrolase_4 PF12146.8 PXF50085.1 - 1.9e-17 63.3 3.3 1.6e-14 53.8 3.3 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PXF50085.1 - 2.1e-12 47.3 0.2 7.6e-07 29.0 0.2 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PXF50085.1 - 5e-12 45.8 0.1 4.6e-11 42.6 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PXF50085.1 - 4.5e-08 34.0 7.6 4.5e-08 34.0 7.6 2.4 2 2 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PXF50085.1 - 2.2e-06 27.5 0.0 0.00062 19.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 PXF50085.1 - 4.2e-06 26.5 0.0 0.054 13.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF829 PF05705.14 PXF50085.1 - 4.1e-05 23.6 0.0 0.00013 21.9 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.16 PXF50085.1 - 0.001 18.9 2.3 0.61 9.8 0.0 3.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 PXF50085.1 - 0.0019 18.1 0.3 0.0042 17.1 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 PXF50085.1 - 0.0085 14.8 0.1 0.33 9.6 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Pro_CA PF00484.19 PXF50085.1 - 0.022 15.0 0.7 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Carbonic anhydrase UPF0227 PF05728.12 PXF50085.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) WES_acyltransf PF03007.16 PXF50085.1 - 0.051 13.3 0.2 0.051 13.3 0.2 2.0 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain OAD_beta PF03977.13 PXF50085.1 - 0.13 11.2 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit RWP-RK PF02042.15 PXF50086.1 - 4.5e-07 29.7 0.0 9.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain NUDIX_5 PF16705.5 PXF50086.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Complex1_LYR PF05347.15 PXF50087.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) WD40 PF00400.32 PXF50088.1 - 8.3e-59 194.2 23.8 4.7e-09 36.7 0.0 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF50088.1 - 3.4e-17 62.5 2.7 0.00034 20.9 0.0 5.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 PXF50088.1 - 2.2e-11 44.1 0.1 3.9e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 PXF50088.1 - 5.8e-10 38.7 2.5 0.03 13.3 0.2 4.9 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PXF50088.1 - 2.1e-07 30.0 10.0 0.072 11.7 0.0 5.6 3 3 2 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 PXF50088.1 - 0.00067 19.6 0.1 0.3 10.9 0.0 3.3 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 PXF50088.1 - 0.002 16.6 0.0 0.74 8.1 0.0 2.9 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 PXF50088.1 - 0.0043 15.6 0.2 0.14 10.6 0.0 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.6 PXF50088.1 - 0.0086 15.4 1.5 4.2 6.6 0.1 4.0 2 2 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Amino_oxidase PF01593.24 PXF50090.1 - 3.6e-76 257.3 0.0 4.1e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PXF50090.1 - 1.4e-16 60.4 0.1 2.5e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PXF50090.1 - 4.9e-07 29.7 0.0 0.00032 20.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 PXF50090.1 - 8.4e-07 29.5 0.1 0.0025 18.4 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PXF50090.1 - 1.2e-06 28.0 0.1 8.7e-05 21.9 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF50090.1 - 0.00072 18.7 0.9 0.0012 18.0 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 PXF50090.1 - 0.0012 17.4 0.1 0.0023 16.4 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 PXF50090.1 - 0.0014 17.4 0.4 0.0041 15.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 PXF50090.1 - 0.0015 17.9 0.1 0.004 16.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 PXF50090.1 - 0.0024 16.7 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 MCRA family Thi4 PF01946.17 PXF50090.1 - 0.0033 16.7 0.1 0.0059 15.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 PXF50090.1 - 0.017 14.5 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PXF50090.1 - 0.065 12.3 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 PXF50090.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 PXF50090.1 - 0.097 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PXF50090.1 - 0.13 11.3 1.0 0.22 10.5 1.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HECT PF00632.25 PXF50091.1 - 3.4e-66 223.8 0.0 6.1e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 PXF50091.1 - 1.6e-09 37.4 0.0 0.084 13.0 0.0 4.7 4 1 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PXF50091.1 - 3.3e-05 24.3 0.3 0.038 14.5 0.1 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.22 PXF50091.1 - 0.0005 20.1 0.0 0.034 14.4 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 PXF50091.1 - 0.00052 20.4 0.4 5.3 7.5 0.1 4.3 3 0 0 3 3 3 2 HEAT repeats SWIB PF02201.18 PXF50092.1 - 1.6e-37 127.2 0.0 8.6e-20 70.4 0.0 2.2 2 0 0 2 2 2 2 SWIB/MDM2 domain hDGE_amylase PF14701.6 PXF50092.1 - 0.067 12.3 0.1 1.7 7.7 0.0 2.0 1 1 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain FA_hydroxylase PF04116.13 PXF50094.1 - 2.9e-28 98.8 17.9 2.9e-28 98.8 17.9 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4199 PF13858.6 PXF50094.1 - 1.1 9.7 5.5 0.11 12.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Pkinase PF00069.25 PXF50095.1 - 3.5e-45 154.4 0.0 3.1e-44 151.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50095.1 - 3e-16 59.5 0.1 3.7e-15 55.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PXF50095.1 - 0.084 12.8 4.0 7.1 6.5 0.1 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family HsdM_N PF12161.8 PXF50095.1 - 0.15 12.7 0.0 0.43 11.2 0.0 1.8 2 0 0 2 2 2 0 HsdM N-terminal domain MRP-S23 PF10484.9 PXF50096.1 - 8.2e-11 42.3 0.2 1.4e-10 41.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 PXF50096.1 - 0.00056 19.5 2.7 0.33 10.5 1.0 3.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 Complex1_LYR PF05347.15 PXF50097.1 - 1.3e-17 63.5 1.8 2.5e-17 62.7 1.8 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PXF50097.1 - 4e-05 24.3 0.5 5.9e-05 23.7 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Phytochelatin PF05023.14 PXF50098.1 - 3e-43 147.5 0.0 3.5e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase LRR_6 PF13516.6 PXF50100.1 - 1.5e-23 80.8 4.3 0.00059 19.7 0.0 9.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.6 PXF50100.1 - 8e-06 25.5 5.9 2.5 7.9 0.0 6.0 4 2 1 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 PXF50100.1 - 1.1e-05 25.7 7.3 6 7.4 0.0 6.4 5 3 1 6 6 6 1 Leucine Rich repeats (2 copies) Sigma70_ner PF04546.13 PXF50100.1 - 0.00022 21.2 10.6 0.00039 20.4 9.8 1.9 2 0 0 2 2 2 1 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 PXF50100.1 - 0.0034 15.6 5.5 0.0048 15.1 5.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen LRR_1 PF00560.33 PXF50100.1 - 0.009 16.4 7.5 10 7.1 0.0 6.5 9 1 0 9 9 5 0 Leucine Rich Repeat DUF5520 PF17658.1 PXF50100.1 - 0.016 14.3 2.5 0.022 13.9 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Cwf_Cwc_15 PF04889.12 PXF50100.1 - 0.022 14.5 11.2 0.032 14.0 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.11 PXF50100.1 - 0.029 12.8 3.8 0.037 12.5 3.8 1.1 1 0 0 1 1 1 0 SGT1 protein CobT PF06213.12 PXF50100.1 - 0.28 10.5 16.9 0.53 9.6 16.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GCIP PF13324.6 PXF50100.1 - 0.43 10.1 15.4 0.84 9.2 15.4 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 PXF50100.1 - 0.74 8.0 18.1 1 7.5 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 PXF50100.1 - 0.78 9.0 11.9 1.2 8.4 11.9 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 PXF50100.1 - 0.91 7.5 28.2 1.3 7.0 28.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 PXF50100.1 - 1.1 9.5 17.4 1.4 9.2 15.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.8 PXF50100.1 - 1.3 9.2 18.5 2.1 8.5 18.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 PXF50100.1 - 1.4 8.0 26.9 2 7.5 26.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NUT PF12881.7 PXF50100.1 - 1.9 6.8 6.0 3.2 6.1 6.0 1.2 1 0 0 1 1 1 0 NUT protein SDA1 PF05285.12 PXF50100.1 - 2.1 7.7 18.0 3.1 7.1 18.0 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 PXF50100.1 - 2.1 6.5 15.4 3.1 6.0 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 PXF50100.1 - 2.3 7.1 5.7 3.1 6.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RPN2_C PF18004.1 PXF50100.1 - 2.5 8.0 6.0 3.9 7.4 6.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Paf1 PF03985.13 PXF50100.1 - 2.9 6.8 12.3 4.2 6.3 12.3 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 PXF50100.1 - 3 7.1 22.7 4.4 6.5 22.7 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 PXF50100.1 - 3.8 7.5 11.5 7.2 6.6 11.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.11 PXF50100.1 - 4.1 6.9 15.6 6.4 6.3 15.6 1.2 1 0 0 1 1 1 0 PPP4R2 Atx10homo_assoc PF09759.9 PXF50101.1 - 3.9e-15 55.7 3.8 2.6e-05 24.2 0.2 5.0 3 2 2 5 5 5 4 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 PXF50101.1 - 2e-14 53.0 1.4 0.00065 19.7 0.0 5.9 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 PXF50101.1 - 0.0082 16.1 1.3 1.2 9.1 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3361) Med26 PF08711.11 PXF50101.1 - 0.031 14.3 0.2 0.4 10.7 0.1 2.7 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF4250 PF14056.6 PXF50101.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) BAG PF02179.16 PXF50102.1 - 1.9e-07 31.4 0.2 4e-06 27.2 0.2 2.0 1 1 0 1 1 1 1 BAG domain PilJ PF13675.6 PXF50102.1 - 0.019 15.0 1.1 0.029 14.4 0.7 1.5 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term MscS_porin PF12795.7 PXF50102.1 - 0.071 12.6 6.4 0.23 11.0 6.4 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain STAT_alpha PF01017.20 PXF50102.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain zf-RING_2 PF13639.6 PXF50103.1 - 2.9e-06 27.5 8.4 5.2e-06 26.7 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PXF50103.1 - 2.1e-05 24.3 8.1 4.3e-05 23.3 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PXF50103.1 - 4.6e-05 23.3 5.0 9.3e-05 22.4 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PXF50103.1 - 0.00026 20.7 8.4 0.00057 19.7 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PXF50103.1 - 0.00082 19.2 7.7 0.0019 18.0 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 PXF50103.1 - 0.002 17.9 3.1 0.0047 16.7 3.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 PXF50103.1 - 0.0077 16.5 4.7 0.017 15.4 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PXF50103.1 - 0.011 15.7 7.8 0.024 14.6 7.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PXF50103.1 - 0.028 14.3 7.2 0.065 13.1 7.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PXF50103.1 - 0.066 13.3 3.2 0.13 12.4 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PXF50103.1 - 0.81 9.9 6.7 1.4 9.1 6.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 PXF50103.1 - 0.97 9.5 6.6 2.9 8.0 6.5 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Zn-ribbon_8 PF09723.10 PXF50103.1 - 1.2 9.3 3.6 1 9.5 1.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 PXF50103.1 - 1.3 9.4 6.7 0.2 11.9 0.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CCCH PF00642.24 PXF50104.1 - 1.1e-10 41.1 16.8 6e-06 26.0 3.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PXF50104.1 - 8.7e-07 28.8 12.7 0.002 18.1 2.9 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 PXF50104.1 - 0.0003 20.5 0.0 0.001 18.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 PXF50104.1 - 1.8 8.5 15.6 0.47 10.3 2.6 2.8 2 1 0 2 2 2 0 CCCH-type zinc finger HCO3_cotransp PF00955.21 PXF50105.1 - 2.7e-128 429.0 17.8 1.9e-74 251.4 3.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family Pyr_redox_2 PF07992.14 PXF50106.1 - 9.7e-51 172.7 0.5 1.7e-50 172.0 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PXF50106.1 - 1.2e-26 93.1 0.5 3.7e-26 91.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DEP PF00610.21 PXF50106.1 - 1e-20 73.6 0.2 2e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pyr_redox PF00070.27 PXF50106.1 - 1.2e-11 44.9 0.2 1.2e-11 44.9 0.2 3.6 5 0 0 5 5 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PXF50106.1 - 2.5e-05 23.6 5.1 0.001 18.2 4.4 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PXF50106.1 - 0.00037 19.8 7.8 0.00059 19.2 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 PXF50106.1 - 0.00056 19.3 0.6 0.0041 16.5 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 PXF50106.1 - 0.0018 18.5 1.0 0.0018 18.5 1.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PXF50106.1 - 0.01 14.6 4.2 0.028 13.2 1.8 2.6 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 PXF50106.1 - 0.013 15.4 0.2 0.013 15.4 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PXF50106.1 - 0.053 13.7 0.4 0.15 12.2 0.3 1.9 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 PXF50106.1 - 0.12 12.0 4.1 3.8 7.0 0.9 2.9 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 PXF50106.1 - 0.16 11.3 3.6 0.31 10.3 3.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 PXF50106.1 - 0.18 12.4 0.8 2.7 8.6 0.1 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 PXF50106.1 - 0.51 9.4 6.8 0.91 8.5 5.9 1.8 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 PXF50106.1 - 1.4 8.2 9.8 5.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Exostosin PF03016.15 PXF50109.1 - 6.1e-09 35.5 0.1 2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Exostosin family Glyco_trans_1_2 PF13524.6 PXF50109.1 - 0.038 14.4 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 TMEM171 PF15471.6 PXF50109.1 - 0.15 11.0 0.7 0.5 9.3 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 ApbE PF02424.15 PXF50110.1 - 8.1e-39 133.7 0.0 1.6e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 ApbE family Flavin_Reduct PF01613.18 PXF50110.1 - 3.7e-08 33.6 8.9 5.1e-06 26.6 2.5 3.3 2 2 0 2 2 2 2 Flavin reductase like domain adh_short PF00106.25 PXF50114.1 - 8.5e-27 93.9 0.3 1.6e-23 83.2 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PXF50114.1 - 4.3e-20 72.3 0.1 5.8e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PXF50114.1 - 5.5e-12 46.0 0.3 8.7e-12 45.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PXF50114.1 - 4.1e-07 29.7 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PXF50114.1 - 5.8e-05 22.6 0.1 0.00013 21.5 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase E1-E2_ATPase PF00122.20 PXF50115.1 - 1.1e-23 83.7 0.6 2.3e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PXF50115.1 - 1.3e-15 58.2 0.0 1.7e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PXF50115.1 - 6.7e-05 22.5 0.0 0.011 15.4 0.0 2.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PXF50115.1 - 0.0051 16.9 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Pox_P21 PF05313.12 PXF50115.1 - 0.019 14.5 1.1 0.05 13.2 1.1 1.6 1 0 0 1 1 1 0 Poxvirus P21 membrane protein RNA_pol_Rpc34 PF05158.12 PXF50116.1 - 2e-57 195.1 5.4 1.9e-37 129.4 0.1 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit HTH_27 PF13463.6 PXF50116.1 - 0.048 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 PXF50116.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 MarR family MFS_1 PF07690.16 PXF50117.1 - 1e-19 70.7 44.3 1e-19 70.7 44.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PXF50117.1 - 0.082 11.8 21.3 0.21 10.4 6.0 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter Ilm1 PF10311.9 PXF50118.1 - 0.0004 20.1 0.3 0.00042 20.0 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Bac_export_2 PF01312.19 PXF50118.1 - 0.0081 15.4 0.7 0.009 15.3 0.7 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family PAP2 PF01569.21 PXF50119.1 - 2.5e-28 98.6 6.2 3.5e-28 98.1 3.9 2.0 1 1 1 2 2 2 1 PAP2 superfamily Transglut_core PF01841.19 PXF50120.1 - 8.5e-13 48.7 0.3 6.8e-12 45.8 0.1 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 PXF50120.1 - 2.1e-05 24.2 0.2 7.3e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain PAW PF04721.17 PXF50120.1 - 0.27 11.0 2.4 0.48 10.2 2.4 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW JAB PF01398.21 PXF50121.1 - 3e-30 104.6 0.1 5.4e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 PXF50121.1 - 9.1e-14 52.1 0.2 1.5e-13 51.4 0.2 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 PXF50121.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PXF50121.1 - 0.099 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Fe_hyd_lg_C PF02906.14 PXF50122.1 - 1.5e-59 201.6 0.0 2.1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Glyco_transf_7C PF02709.14 PXF50123.1 - 1e-05 25.1 0.0 2.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 PXF50123.1 - 0.00084 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 PXF50123.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF4229 PF14012.6 PXF50123.1 - 0.13 12.3 0.5 0.26 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) IP_trans PF02121.18 PXF50124.1 - 5.2e-96 321.0 1.5 6e-96 320.8 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Band_7 PF01145.25 PXF50125.1 - 1.5e-25 90.2 3.5 2.5e-25 89.5 3.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Myosin-VI_CBD PF16521.5 PXF50125.1 - 0.024 14.6 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Myosin VI cargo binding domain Peptidase_S66 PF02016.15 PXF50125.1 - 0.14 12.3 0.2 0.38 10.9 0.2 1.7 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain UTP25 PF06862.12 PXF50126.1 - 2e-140 468.7 2.1 7.8e-88 295.3 0.5 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PROCN PF08083.11 PXF50127.1 - 9e-223 739.3 7.5 1.4e-222 738.7 7.5 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 PXF50127.1 - 1.7e-122 407.4 0.2 2.9e-122 406.6 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 PXF50127.1 - 1.1e-83 278.6 3.5 3.3e-83 277.1 2.9 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 PXF50127.1 - 2.6e-83 277.7 2.9 7.3e-83 276.3 2.9 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 PXF50127.1 - 1e-69 232.8 0.0 2.5e-69 231.5 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 PXF50127.1 - 6.6e-44 148.2 0.3 1.9e-43 146.7 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 PXF50127.1 - 2.1e-42 143.9 0.1 6.1e-42 142.4 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 PXF50127.1 - 0.00074 19.5 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BH4 PF02180.17 PXF50127.1 - 0.13 12.1 0.8 0.31 10.9 0.8 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 Cpn60_TCP1 PF00118.24 PXF50128.1 - 5.8e-154 513.3 4.5 6.6e-154 513.2 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3598 PF12204.8 PXF50129.1 - 6.3e-23 81.6 0.0 7.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3598) NT5C PF06941.12 PXF50130.1 - 5.2e-15 55.8 0.0 1.5e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 PXF50130.1 - 0.055 13.6 0.5 0.089 12.9 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NIF PF03031.18 PXF50130.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Hydrolase PF00702.26 PXF50130.1 - 0.16 12.2 0.2 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RNA_pol_Rpb1_3 PF04983.18 PXF50132.1 - 9.8e-43 145.8 0.0 1.5e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.20 PXF50132.1 - 6e-42 143.7 1.0 5.4e-41 140.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 PXF50132.1 - 8.5e-30 102.9 0.0 2.2e-29 101.5 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 4 Topoisom_I PF01028.20 PXF50133.1 - 5.6e-95 317.0 0.4 1.3e-94 315.8 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 PXF50133.1 - 3.5e-82 275.0 2.6 3.5e-82 275.0 2.6 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 PXF50133.1 - 3.2e-33 113.5 0.7 1.1e-32 111.7 0.7 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain SART-1 PF03343.13 PXF50134.1 - 1.8e-44 152.4 47.8 6.9e-20 71.2 0.4 5.1 2 1 3 5 5 5 5 SART-1 family DUF1380 PF07128.12 PXF50135.1 - 0.096 12.9 2.7 4.8 7.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) Branch PF02485.21 PXF50136.1 - 9.7e-36 123.5 2.5 1.3e-35 123.1 2.5 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TPR_2 PF07719.17 PXF50137.1 - 1.9e-24 83.7 4.2 2e-05 24.4 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 PXF50137.1 - 5e-22 76.7 1.4 7.2e-06 25.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PXF50137.1 - 4.9e-15 55.6 7.4 2e-06 28.0 0.3 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PXF50137.1 - 9.2e-15 55.0 30.8 3.2e-06 27.7 6.5 4.3 2 1 2 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 PXF50137.1 - 9.6e-14 50.8 9.3 0.00065 19.3 1.2 5.6 1 1 5 6 6 6 3 TPR repeat TPR_19 PF14559.6 PXF50137.1 - 1.6e-13 50.9 10.6 1.6e-06 28.5 1.5 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PXF50137.1 - 5.8e-12 45.1 7.7 2.9e-05 24.1 0.2 5.9 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 PXF50137.1 - 9.4e-12 44.9 11.3 0.0002 21.5 1.5 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 PXF50137.1 - 1.7e-10 40.8 17.9 0.034 15.0 0.9 5.9 1 1 4 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 PXF50137.1 - 4.4e-10 39.2 9.4 0.44 11.3 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PXF50137.1 - 3.5e-09 36.1 0.3 0.18 12.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 PXF50137.1 - 4e-09 36.0 19.5 0.0024 17.7 0.2 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PXF50137.1 - 2.6e-08 34.0 11.8 0.63 10.8 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 PXF50137.1 - 1e-06 28.3 8.2 0.082 13.0 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PXF50137.1 - 3.8e-05 23.1 3.1 0.81 9.2 0.2 3.9 4 0 0 4 4 4 2 SHNi-TPR TPR_15 PF13429.6 PXF50137.1 - 0.0001 21.6 15.1 0.012 14.8 0.0 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PXF50137.1 - 0.0029 17.0 7.7 2.3 7.5 0.3 3.8 1 1 2 4 4 4 3 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 PXF50137.1 - 0.0055 17.2 1.0 0.015 15.7 0.3 2.0 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation NARP1 PF12569.8 PXF50137.1 - 0.0066 15.4 0.1 2.1 7.2 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 PXF50137.1 - 0.0095 16.1 2.9 1.3 9.3 0.0 3.8 1 1 4 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 PXF50137.1 - 0.016 15.0 0.5 3.3 7.4 0.0 3.3 3 1 0 4 4 4 0 26S proteasome subunit RPN7 MIT PF04212.18 PXF50137.1 - 0.041 13.9 1.4 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 PXF50137.1 - 0.38 10.4 15.0 0.25 11.1 1.1 3.7 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 PXF50137.1 - 1.4 8.8 10.3 4.3 7.2 5.1 2.6 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ERCC4 PF02732.15 PXF50138.1 - 4.8e-13 49.6 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 PXF50138.1 - 0.0019 18.5 0.3 0.024 15.0 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 PXF50138.1 - 0.14 12.1 0.0 8.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif FA_desaturase PF00487.24 PXF50139.1 - 1e-22 81.2 22.8 1e-22 81.2 22.8 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 PXF50139.1 - 2.4e-08 33.3 0.1 5.4e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pyr_redox_2 PF07992.14 PXF50140.1 - 1.1e-28 100.4 0.1 1.3e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PXF50140.1 - 2e-08 34.7 0.4 8.4e-08 32.7 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PXF50140.1 - 0.00057 19.6 3.6 0.29 10.7 0.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PXF50140.1 - 0.0021 16.9 1.4 1 8.0 0.1 2.7 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 PXF50140.1 - 0.0033 16.7 0.1 0.0093 15.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PXF50140.1 - 0.004 16.3 1.4 0.0055 15.8 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PXF50140.1 - 0.01 15.0 0.4 0.31 10.1 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 PXF50140.1 - 0.026 14.5 1.4 11 5.9 0.2 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 PXF50140.1 - 0.042 13.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4147 PF13660.6 PXF50140.1 - 0.077 12.5 0.1 0.21 11.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4147) Lycopene_cycl PF05834.12 PXF50140.1 - 0.58 9.1 3.3 1.4 7.9 1.7 2.3 2 1 1 3 3 3 0 Lycopene cyclase protein LysE PF01810.18 PXF50141.1 - 0.0099 15.4 0.4 0.02 14.4 0.3 1.7 1 1 0 1 1 1 1 LysE type translocator Cnd2 PF05786.14 PXF50142.1 - 7.2e-111 372.2 0.8 1.6e-108 364.4 0.8 2.4 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 PXF50142.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal BLUF PF04940.12 PXF50143.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Sensors of blue-light using FAD ZZ PF00569.17 PXF50144.1 - 0.0048 16.7 1.4 0.0048 16.7 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type PG_binding_1 PF01471.18 PXF50144.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain C1_2 PF03107.16 PXF50144.1 - 0.43 10.9 5.4 0.88 9.9 5.4 1.5 1 0 0 1 1 1 0 C1 domain PB1 PF00564.24 PXF50145.1 - 6.5e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 PXF50145.1 - 2.5e-11 43.2 3.5 4.3e-11 42.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type PG_binding_1 PF01471.18 PXF50145.1 - 6.9e-09 35.8 0.1 1.6e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain FAM75 PF14650.6 PXF50145.1 - 0.056 13.0 22.6 0.11 12.0 22.6 1.4 1 0 0 1 1 1 0 FAM75 family DUF3391 PF11871.8 PXF50145.1 - 0.16 12.5 2.8 0.35 11.4 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TFIIA PF03153.13 PXF50145.1 - 0.26 11.2 10.4 0.51 10.3 10.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2057 PF09829.9 PXF50145.1 - 0.26 11.4 4.5 0.17 12.0 1.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Spt20 PF12090.8 PXF50145.1 - 1.6 8.3 10.4 2.5 7.6 10.4 1.3 1 0 0 1 1 1 0 Spt20 family DUF5327 PF17261.2 PXF50145.1 - 2 9.2 5.2 5.8 7.7 5.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) WD40 PF00400.32 PXF50147.1 - 2e-10 41.1 3.3 0.35 11.8 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PXF50147.1 - 0.09 11.7 0.0 1.4 7.8 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1797 PF08796.10 PXF50147.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) GARS_N PF02844.15 PXF50148.1 - 6.8e-07 30.0 0.0 1.1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain DUF498 PF04430.14 PXF50148.1 - 0.0076 16.3 0.0 0.13 12.3 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF498/DUF598) TTR-52 PF01060.23 PXF50150.1 - 0.052 14.2 0.1 0.17 12.6 0.0 1.9 2 0 0 2 2 2 0 Transthyretin-like family ketoacyl-synt PF00109.26 PXF50151.1 - 3.9e-55 187.2 0.3 3.9e-55 187.2 0.3 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PXF50151.1 - 7.3e-32 109.9 1.3 1.3e-31 109.0 1.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PXF50151.1 - 0.0013 18.1 1.5 0.0046 16.4 0.4 2.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 PXF50151.1 - 0.049 14.1 0.2 0.16 12.5 0.2 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Thioredoxin PF00085.20 PXF50152.1 - 2.7e-29 101.2 0.0 5.9e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 PXF50152.1 - 9.6e-12 44.9 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 PXF50152.1 - 7.4e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DIM1 PF02966.16 PXF50152.1 - 0.00028 20.7 0.0 0.00061 19.6 0.0 1.5 2 0 0 2 2 2 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 PXF50152.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PXF50152.1 - 0.0035 17.2 0.0 0.0096 15.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 PXF50152.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 PXF50152.1 - 0.038 14.2 0.0 0.038 14.2 0.0 2.8 3 1 0 3 3 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 PXF50152.1 - 0.053 14.0 1.3 0.19 12.2 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain ERM PF00769.19 PXF50152.1 - 0.08 12.7 30.2 0.38 10.5 4.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family TraF PF13728.6 PXF50152.1 - 0.55 10.0 0.0 0.55 10.0 0.0 4.2 3 2 1 4 4 2 0 F plasmid transfer operon protein EPL1 PF10513.9 PXF50152.1 - 1.3 9.4 7.8 0.46 10.9 1.6 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like UPF0242 PF06785.11 PXF50152.1 - 2.4 8.2 9.3 4.2 7.4 9.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Vfa1 PF08432.10 PXF50152.1 - 3.2 8.0 18.4 0.95 9.8 8.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 PXF50152.1 - 6.6 6.0 36.0 0.69 9.2 8.1 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Hydin_ADK PF17213.3 PXF50152.1 - 8.4 6.6 17.4 2.8 8.2 3.8 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IF4E PF01652.18 PXF50153.1 - 2.4e-45 154.2 0.0 2.9e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HEAT_2 PF13646.6 PXF50154.1 - 7.9e-33 112.7 16.9 2.7e-13 50.1 0.9 4.0 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 PXF50154.1 - 5.2e-26 88.6 2.7 0.0025 18.3 0.0 6.8 7 0 0 7 7 7 6 PBS lyase HEAT-like repeat HEAT PF02985.22 PXF50154.1 - 1.9e-09 37.0 7.8 0.054 13.8 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 PXF50154.1 - 7.4e-09 35.9 2.5 0.15 12.6 0.0 5.3 4 2 2 6 6 6 4 HEAT-like repeat Arm PF00514.23 PXF50154.1 - 0.00026 20.9 0.0 0.075 13.1 0.0 2.9 2 1 0 2 2 2 1 Armadillo/beta-catenin-like repeat DDE_Tnp_1_4 PF13701.6 PXF50154.1 - 0.0013 17.1 0.8 0.002 16.5 0.2 1.5 2 0 0 2 2 2 1 Transposase DDE domain group 1 Inhibitor_I10 PF12559.8 PXF50154.1 - 0.017 15.3 0.0 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 Serine endopeptidase inhibitors ADH_N_2 PF16884.5 PXF50155.1 - 5.6e-25 87.3 0.0 2.2e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PXF50155.1 - 4.3e-18 65.5 0.4 1e-17 64.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PXF50155.1 - 1.7e-11 45.3 0.0 3.7e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase IBN_N PF03810.19 PXF50156.1 - 0.16 11.9 0.2 0.52 10.3 0.2 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain NYN_YacP PF05991.11 PXF50157.1 - 1.3e-40 139.1 0.3 2.1e-40 138.4 0.3 1.3 1 0 0 1 1 1 1 YacP-like NYN domain TFIIS_M PF07500.14 PXF50158.1 - 1.9e-30 105.6 3.9 2.7e-30 105.1 3.9 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 PXF50158.1 - 5.1e-19 67.9 8.9 1.1e-18 66.8 8.9 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) SUIM_assoc PF16619.5 PXF50158.1 - 0.0029 17.7 1.5 0.007 16.4 1.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 C1_4 PF07975.12 PXF50158.1 - 2.2 8.6 6.3 1.5 9.2 1.8 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain RNase_P_p30 PF01876.16 PXF50160.1 - 9.7e-43 146.1 0.0 1.1e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit p30 PDZ_3 PF17815.1 PXF50161.1 - 4.1e-44 150.0 0.0 7.2e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PXF50161.1 - 1.9e-22 80.8 1.5 4e-22 79.7 0.2 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PXF50161.1 - 1e-13 51.6 0.1 2.1e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PXF50161.1 - 6.7e-11 42.4 0.1 1.2e-09 38.4 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PXF50161.1 - 8.4e-07 29.3 0.0 1.2e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PXF50161.1 - 0.00016 21.5 0.0 0.015 15.1 0.1 2.7 2 0 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 PXF50161.1 - 0.0051 16.6 0.0 0.021 14.6 0.1 1.9 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 PXF50161.1 - 0.0053 16.6 0.6 0.012 15.5 0.6 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Pkinase PF00069.25 PXF50162.1 - 2e-55 188.0 0.0 4.6e-55 186.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50162.1 - 6.9e-21 74.7 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PXF50162.1 - 0.00095 18.8 0.2 0.0027 17.3 0.2 1.7 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PXF50162.1 - 0.013 15.4 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 PXF50162.1 - 0.14 11.7 0.3 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RNase_PH PF01138.21 PXF50163.1 - 6.1e-36 123.8 0.0 2.8e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 PXF50163.1 - 2.1e-16 60.0 2.6 2.7e-16 59.7 0.9 2.0 2 0 0 2 2 2 1 S1 RNA binding domain RNase_PH_C PF03725.15 PXF50163.1 - 6.4e-11 42.1 0.1 1.5e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 PNPase PF03726.14 PXF50163.1 - 1.3e-09 38.4 0.2 3.3e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 PXF50163.1 - 1.9e-06 27.6 2.8 6.4e-06 25.9 2.8 2.0 1 0 0 1 1 1 1 KH domain S1_2 PF13509.6 PXF50163.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 S1 domain FlbT PF07378.11 PXF50163.1 - 0.062 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Flagellar protein FlbT TFIID-18kDa PF02269.16 PXF50164.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DTW PF03942.15 PXF50165.1 - 3.1e-20 72.7 0.0 1.1e-19 71.0 0.0 1.8 1 1 0 1 1 1 1 DTW domain Tim17 PF02466.19 PXF50166.1 - 3.8e-08 33.7 7.5 7e-08 32.8 7.5 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family tRNA-synt_2 PF00152.20 PXF50167.1 - 1.9e-80 270.3 0.0 2.4e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PXF50167.1 - 4.9e-10 39.3 0.1 1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PXF50167.1 - 3.8e-06 26.6 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) KfrA_N PF11740.8 PXF50167.1 - 0.01 16.5 10.1 0.019 15.7 9.3 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term RRN3 PF05327.11 PXF50169.1 - 1.5e-23 83.2 0.9 4.7e-11 41.9 0.3 2.1 2 0 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 FlaC_arch PF05377.11 PXF50169.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Big_7 PF17957.1 PXF50170.1 - 0.00045 20.9 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial Ig domain Hist_deacetyl PF00850.19 PXF50172.1 - 5.8e-63 213.2 0.0 7.7e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF5633 PF18656.1 PXF50172.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5633) LSM PF01423.22 PXF50174.1 - 3e-15 55.6 0.4 4.5e-15 55.1 0.4 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PXF50174.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Hfq protein Nuc_sug_transp PF04142.15 PXF50174.1 - 0.13 11.4 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter GST_N_3 PF13417.6 PXF50175.1 - 6.9e-11 42.4 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PXF50175.1 - 1.1e-09 38.3 0.8 2.5e-09 37.2 0.8 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 PXF50175.1 - 4.4e-06 26.9 0.0 8.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PXF50175.1 - 7.5e-06 26.6 0.0 2.5e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 PXF50175.1 - 7.3e-05 22.7 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PXF50175.1 - 0.00034 20.7 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PXF50175.1 - 0.00091 19.5 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PXF50175.1 - 0.0039 17.4 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fer4_14 PF13394.6 PXF50176.1 - 7e-13 48.7 0.2 1e-11 45.0 0.2 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 PXF50176.1 - 1.1e-11 45.5 0.0 1.8e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 PXF50176.1 - 3.3e-11 43.6 0.0 7.1e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain WD40 PF00400.32 PXF50177.1 - 2.2e-17 63.1 10.4 6.3e-05 23.7 0.1 5.0 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PXF50177.1 - 0.00027 21.2 2.3 0.36 11.2 0.1 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 PXF50178.1 - 3.5e-27 95.6 0.0 7.2e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PXF50178.1 - 6.1e-07 29.6 0.9 0.016 15.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PXF50178.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PXF50178.1 - 0.011 15.4 0.3 0.019 14.7 0.3 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 PXF50178.1 - 0.048 13.8 0.2 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 PXF50178.1 - 0.097 13.0 0.3 0.16 12.3 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PXF50178.1 - 0.11 12.7 0.7 0.36 11.1 0.5 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 PXF50178.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Pkinase PF00069.25 PXF50179.1 - 7.7e-55 186.1 0.1 1.2e-54 185.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PXF50179.1 - 1.1e-23 83.8 0.1 2e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 PXF50179.1 - 4.1e-08 33.2 0.4 1.2e-07 31.7 0.4 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 RIO1 PF01163.22 PXF50179.1 - 0.00015 21.4 1.3 0.0032 17.1 0.1 2.6 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 PXF50179.1 - 0.02 14.5 0.1 0.94 9.1 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4407 PF14362.6 PXF50179.1 - 0.058 12.8 11.7 0.13 11.6 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_11 PF13414.6 PXF50179.1 - 0.074 12.8 0.3 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 TPR repeat APH PF01636.23 PXF50179.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family DUF1773 PF08593.10 PXF50179.1 - 0.37 11.9 1.6 1.5 9.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function SET PF00856.28 PXF50180.1 - 5.3e-18 66.0 0.1 5.3e-18 66.0 0.1 4.0 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 PXF50180.1 - 0.0015 18.3 0.0 0.0043 16.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.21 PXF50181.1 - 7.1e-62 208.8 0.2 1.9e-60 204.1 0.1 2.9 3 1 0 3 3 3 1 MutS domain V MutS_III PF05192.18 PXF50181.1 - 3e-27 96.1 1.1 3e-27 96.1 1.1 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PXF50181.1 - 3.3e-27 95.0 0.0 2.1e-26 92.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 PXF50181.1 - 4.6e-12 46.4 0.1 1.4e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 PXF50181.1 - 2.6e-06 27.7 0.0 1.2e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV FANCI_S2 PF14676.6 PXF50182.1 - 1.5e-12 48.2 0.2 1.5e-12 48.2 0.2 2.9 2 1 0 2 2 2 1 FANCI solenoid 2 Closter_coat PF01785.17 PXF50182.1 - 4.7 6.4 6.5 1.7 7.9 0.1 2.7 3 0 0 3 3 3 0 Closterovirus coat protein Cupin_8 PF13621.6 PXF50183.1 - 1.1e-46 159.6 0.1 1.9e-46 158.8 0.1 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PXF50183.1 - 1.4e-09 37.9 0.1 1.6e-08 34.4 0.0 2.6 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.11 PXF50183.1 - 0.00059 19.5 0.0 0.0041 16.8 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 PXF50183.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin EF-hand_8 PF13833.6 PXF50184.1 - 5.2e-10 39.0 1.3 9.3e-05 22.2 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 PXF50184.1 - 2.4e-08 34.3 0.4 4.9e-05 23.7 0.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 PXF50184.1 - 1.9e-06 28.1 0.0 2.3e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 PXF50184.1 - 3.2e-06 26.6 0.1 0.32 11.0 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PXF50184.1 - 0.00013 21.2 1.0 7.5 6.3 0.0 4.7 5 0 0 5 5 5 1 EF hand DUF1002 PF06207.11 PXF50184.1 - 0.043 13.3 0.1 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) EFhand_Ca_insen PF08726.10 PXF50184.1 - 0.056 13.5 0.1 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Ca2+ insensitive EF hand DUF917 PF06032.12 PXF50185.1 - 2.6e-76 256.7 0.2 3e-76 256.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Chromo PF00385.24 PXF50188.1 - 3.8e-10 39.5 0.0 5.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro38C2 PF17677.1 PXF50188.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Rhodophyta/Gracilariopsis_chorda-GraCho1.0/GCA_003194525.1_GraCho1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Rhodophyta/Gracilariopsis_chorda-GraCho1.0/GCA_003194525.1_GraCho1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Rhodophyta/Gracilariopsis_chorda-GraCho1.0/GCA_003194525.1_GraCho1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Rhodophyta/Gracilariopsis_chorda-GraCho1.0/GCA_003194525.1_GraCho1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 11:13:41 2019 # [ok]