# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Clp_N PF02861.15 EME25717.1 - 5.6e-26 90.2 0.9 6.3e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 Clp amino terminal domain TFIID-18kDa PF02269.11 EME25717.1 - 0.00019 21.1 0.0 0.015 15.1 0.0 2.5 3 0 0 3 3 3 2 Transcription initiation factor IID, 18kD subunit Aldedh PF00171.17 EME25720.1 - 1.4e-86 290.7 0.4 1.5e-86 290.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME25720.1 - 0.053 12.7 0.1 0.36 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Glycos_transf_2 PF00535.21 EME25721.1 - 1.9e-09 37.3 0.1 4.2e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 EME25721.1 - 0.0053 17.0 0.3 0.01 16.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mg_trans_NIPA PF05653.9 EME25725.1 - 2.9e-44 151.2 18.8 7e-43 146.7 11.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EME25725.1 - 1.1e-05 25.5 2.7 1.1e-05 25.5 1.9 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EME25725.1 - 3.7e-05 23.7 4.6 3.7e-05 23.7 3.2 3.9 3 1 1 4 4 4 1 EamA-like transporter family Rax2 PF12768.2 EME25725.1 - 0.022 13.9 0.3 0.022 13.9 0.2 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF2371 PF10177.4 EME25725.1 - 0.087 12.6 2.2 2.7 7.8 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Brix PF04427.13 EME25726.1 - 4.7e-13 49.2 0.0 6.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain CotJB PF12652.2 EME25728.1 - 0.071 13.1 0.2 0.19 11.7 0.0 1.8 2 1 0 2 2 2 0 CotJB protein Raptor_N PF14538.1 EME25729.1 - 0.027 14.3 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF2768 PF10966.3 EME25729.1 - 0.059 13.5 0.3 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Arch_ATPase PF01637.13 EME25730.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase DUF1365 PF07103.6 EME25731.1 - 4.3e-41 140.6 2.7 4.8e-41 140.4 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Arch_ATPase PF01637.13 EME25732.1 - 0.00026 20.7 0.0 0.00075 19.2 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase Pro_isomerase PF00160.16 EME25733.1 - 1e-43 149.1 0.1 1.5e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EME25733.1 - 1.5e-11 43.7 0.0 2.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME25733.1 - 3e-08 33.5 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME25733.1 - 8.4e-08 31.9 0.1 2.2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KRE9 PF05390.6 EME25734.1 - 0.12 12.7 0.4 0.12 12.7 0.3 2.0 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Resolvase PF00239.16 EME25735.1 - 5.3e-28 97.6 0.1 9.7e-28 96.7 0.0 1.5 2 0 0 2 2 2 1 Resolvase, N terminal domain HTH_Tnp_1 PF01527.15 EME25735.1 - 0.0081 16.1 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.10 EME25735.1 - 0.0084 15.9 0.2 0.025 14.4 0.2 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF3479 PF11965.3 EME25735.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3479) HTH_11 PF08279.7 EME25735.1 - 0.051 13.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 HTH domain Arch_ATPase PF01637.13 EME25736.1 - 0.0031 17.2 0.0 0.0077 15.9 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EME25736.1 - 0.1 12.7 0.0 1.2 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain ubiquitin PF00240.18 EME25738.1 - 4.7e-09 35.5 0.5 5e-09 35.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME25738.1 - 4.4e-05 23.0 0.3 4.5e-05 23.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Arch_ATPase PF01637.13 EME25742.1 - 0.0001 22.0 0.1 0.00052 19.7 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase E1-E2_ATPase PF00122.15 EME25743.1 - 6.5e-24 84.2 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EME25743.1 - 5.2e-18 66.2 0.0 1.8e-16 61.1 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME25743.1 - 1.5e-16 61.1 0.0 3.4e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME25743.1 - 0.00086 19.2 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME25743.1 - 0.052 13.1 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NMT PF01233.14 EME25744.1 - 6.9e-41 139.5 0.2 3.4e-40 137.3 0.0 2.1 3 0 0 3 3 3 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EME25744.1 - 2.4e-21 76.0 0.1 3.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EME25744.1 - 0.032 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME25744.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME25744.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein AAA_22 PF13401.1 EME25747.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME25749.1 - 0.034 14.3 0.0 0.29 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF4591 PF15261.1 EME25750.1 - 1.7 8.8 6.4 2.2 8.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) FA_desaturase PF00487.19 EME25751.1 - 2.1e-22 79.8 24.8 2.1e-22 79.8 17.2 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.5 EME25751.1 - 1.3e-07 30.7 2.1 3.1e-07 29.5 1.4 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Sugar_tr PF00083.19 EME25752.1 - 8.3e-60 202.6 17.2 9.3e-60 202.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME25752.1 - 0.00015 20.5 13.8 0.00015 20.5 9.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tecti-min-caps PF09300.5 EME25753.1 - 0.087 12.6 0.0 0.087 12.6 0.0 1.0 1 0 0 1 1 1 0 Tectiviridae, minor capsid COX7C PF02935.11 EME25754.1 - 0.045 13.5 0.3 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Cytochrom_B561 PF03188.11 EME25754.1 - 0.066 13.0 1.8 0.079 12.7 0.4 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2207 PF09972.4 EME25754.1 - 0.23 9.9 4.2 0.27 9.7 2.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1654 PF07867.6 EME25755.1 - 0.068 12.5 0.2 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Mer2 PF09074.5 EME25757.1 - 0.055 13.3 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Mer2 Xan_ur_permease PF00860.15 EME25759.1 - 2.6e-64 217.1 32.9 7.8e-44 149.7 11.9 2.3 1 1 1 2 2 2 2 Permease family MOSC PF03473.12 EME25760.1 - 2.2e-09 36.8 0.0 3.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 MOSC domain DNA_topoisoIV PF00521.15 EME25761.1 - 4.5e-51 174.0 0.0 7.1e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EME25761.1 - 3.8e-11 42.5 0.1 1.4e-10 40.6 0.0 1.9 3 0 0 3 3 3 1 DNA gyrase B Toprim PF01751.17 EME25761.1 - 5.3e-08 32.7 0.0 2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EME25761.1 - 8.9e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF230 PF03003.11 EME25762.1 - 0.026 14.0 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function Arch_ATPase PF01637.13 EME25764.1 - 0.00038 20.2 0.0 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase Arch_ATPase PF01637.13 EME25766.1 - 0.00039 20.1 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase Arch_ATPase PF01637.13 EME25767.1 - 0.035 13.8 0.3 0.15 11.6 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EME25770.1 - 0.0073 16.4 0.0 0.044 13.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME25770.1 - 0.036 13.9 0.5 0.087 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Wbp11 PF09429.5 EME25771.1 - 1.1 9.2 16.5 1.7 8.6 1.7 3.7 3 0 0 3 3 3 0 WW domain binding protein 11 DUF1654 PF07867.6 EME25772.1 - 0.055 12.8 0.2 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Uricase PF01014.13 EME25777.1 - 1.9e-49 167.2 0.1 1.8e-24 86.3 0.0 2.0 2 0 0 2 2 2 2 Uricase FolB PF02152.13 EME25777.1 - 0.0011 19.1 0.2 0.0058 16.7 0.0 2.3 3 0 0 3 3 3 1 Dihydroneopterin aldolase Xan_ur_permease PF00860.15 EME25778.1 - 1.1e-23 83.4 15.7 3e-21 75.3 5.3 2.0 1 1 1 2 2 2 2 Permease family MerT PF02411.10 EME25778.1 - 0.0038 17.0 0.2 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 MerT mercuric transport protein Arch_ATPase PF01637.13 EME25781.1 - 4.3e-06 26.6 0.1 2.7e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 Archaeal ATPase RVT_connect PF06815.8 EME25783.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase connection domain CAP_N PF01213.14 EME25784.1 - 0.0062 15.8 3.1 0.0077 15.5 2.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Cytomega_UL20A PF05984.7 EME25784.1 - 2.2 8.5 4.7 6.9 6.9 3.3 2.0 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein Grp1_Fun34_YaaH PF01184.14 EME25785.1 - 5e-25 88.0 20.2 6.8e-25 87.6 14.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CGI-121 PF08617.5 EME25786.1 - 2.8e-23 82.3 0.2 3.2e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Amino_oxidase PF01593.19 EME25787.1 - 4.7e-22 78.6 0.0 5e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DUF2340 PF10209.4 EME25789.1 - 4.5e-30 104.3 0.1 5.2e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) CBM_48 PF02922.13 EME25791.1 - 0.0047 16.9 0.1 0.0095 15.9 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PEGA PF08308.6 EME25791.1 - 0.031 14.0 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 PEGA domain MDFI PF15316.1 EME25791.1 - 0.32 10.9 3.8 0.4 10.6 2.6 1.1 1 0 0 1 1 1 0 MyoD family inhibitor PcfK PF14058.1 EME25791.1 - 0.82 9.8 8.3 1.2 9.2 5.7 1.2 1 0 0 1 1 1 0 PcfK-like protein Arch_ATPase PF01637.13 EME25796.1 - 0.0081 15.8 0.2 0.074 12.7 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase Arch_ATPase PF01637.13 EME25798.1 - 0.0011 18.7 0.0 0.004 16.8 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase Adeno_terminal PF02459.10 EME25801.1 - 0.015 13.5 0.7 0.02 13.0 0.5 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein AAA_22 PF13401.1 EME25802.1 - 0.0028 17.7 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AA_permease_2 PF13520.1 EME25805.1 - 8.3e-29 100.3 69.5 1e-28 100.0 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME25805.1 - 3e-26 91.7 65.5 9.7e-26 90.1 45.4 1.6 1 1 0 1 1 1 1 Amino acid permease DUF1980 PF09323.5 EME25806.1 - 0.022 14.4 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Na_Ca_ex PF01699.19 EME25806.1 - 0.037 13.6 0.2 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Multi_Drug_Res PF00893.14 EME25806.1 - 0.06 13.8 0.5 0.089 13.2 0.4 1.2 1 0 0 1 1 1 0 Small Multidrug Resistance protein CD20 PF04103.10 EME25806.1 - 0.2 11.5 3.8 0.34 10.8 2.6 1.4 1 0 0 1 1 1 0 CD20-like family Aa_trans PF01490.13 EME25807.1 - 2.5e-19 69.0 11.5 2.8e-19 68.9 7.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Arch_ATPase PF01637.13 EME25811.1 - 0.046 13.4 0.0 0.42 10.2 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase 2C_adapt PF08793.5 EME25812.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 2-cysteine adaptor domain DUF1510 PF07423.6 EME25812.1 - 3.1 7.1 16.3 8.1 5.7 11.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Thy1 PF02511.10 EME25813.1 - 3.7e-41 140.5 1.7 4.6e-41 140.2 1.2 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein DUF968 PF06147.6 EME25813.1 - 0.062 13.2 0.2 0.15 11.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF968) AAA_22 PF13401.1 EME25814.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain TRAPPC-Trs85 PF12739.2 EME25816.1 - 1.7e-45 155.4 0.7 3.5e-45 154.3 0.5 1.5 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_8 PF13181.1 EME25816.1 - 2.8e-06 26.7 6.9 0.037 13.7 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME25816.1 - 0.00015 21.2 8.7 0.013 15.0 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 EME25816.1 - 0.00051 19.2 0.9 0.03 13.4 0.0 2.4 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EME25816.1 - 0.00096 18.7 0.7 0.093 12.5 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME25816.1 - 0.0014 18.2 9.3 0.0028 17.2 0.1 3.5 3 1 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EME25816.1 - 0.0069 16.2 0.5 0.0069 16.2 0.3 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME25816.1 - 0.023 15.0 0.8 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EME25816.1 - 0.044 13.2 3.0 1 8.7 0.2 2.4 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_3 PF07720.7 EME25816.1 - 0.053 13.3 2.6 0.41 10.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME25816.1 - 0.055 13.9 0.1 6.5 7.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME25816.1 - 0.099 12.5 0.1 0.099 12.5 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME25816.1 - 0.23 12.1 3.0 7.9 7.4 0.1 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EME25816.1 - 0.32 11.1 8.9 2.7 8.1 0.1 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EME25816.1 - 2.2 9.0 8.4 0.8 10.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EME25817.1 - 2e-17 62.9 8.7 2.4e-17 62.6 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME25817.1 - 5.9e-09 35.1 15.1 7.2e-09 34.8 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME25817.1 - 0.0011 17.4 2.0 0.0014 17.1 1.4 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein SNN_transmemb PF09049.5 EME25817.1 - 0.55 9.9 6.8 0.13 11.9 1.7 2.2 2 0 0 2 2 2 0 Stannin transmembrane UBA PF00627.26 EME25818.1 - 3.6e-06 26.6 0.1 8.8e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EME25818.1 - 0.00034 20.0 0.2 0.0008 18.8 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain DUF1296 PF06972.6 EME25818.1 - 0.0068 16.3 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) CUE PF02845.11 EME25818.1 - 0.01 15.3 0.2 0.026 14.0 0.1 1.8 1 0 0 1 1 1 1 CUE domain HABP4_PAI-RBP1 PF04774.10 EME25819.1 - 0.017 15.5 2.3 0.036 14.5 1.6 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family MMR_HSR1 PF01926.18 EME25824.1 - 4.3e-20 71.7 0.3 1.6e-15 57.1 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 EME25824.1 - 1.1e-16 60.4 17.9 3.9e-16 58.7 12.4 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 EME25824.1 - 2.4e-09 36.6 0.1 2e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EME25824.1 - 9.4e-05 22.8 0.6 0.056 13.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EME25824.1 - 0.00032 20.5 9.5 0.0063 16.3 0.0 3.5 2 2 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EME25824.1 - 0.0039 16.3 0.5 0.017 14.2 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME25824.1 - 0.023 14.1 8.3 0.036 13.4 0.2 3.6 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EME25824.1 - 0.025 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME25824.1 - 0.044 13.7 0.4 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Beta_protein PF14350.1 EME25824.1 - 0.11 11.6 3.4 0.17 10.9 2.4 1.3 1 0 0 1 1 1 0 Beta protein ArgK PF03308.11 EME25824.1 - 0.17 10.6 0.0 0.17 10.6 0.0 2.6 2 1 0 2 2 2 0 ArgK protein Nop25 PF09805.4 EME25824.1 - 0.26 11.3 13.4 0.62 10.1 9.3 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Mit_KHE1 PF10173.4 EME25824.1 - 1.8 8.4 9.0 1 9.1 4.2 1.9 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4366 PF14283.1 EME25825.1 - 0.00049 19.5 0.0 0.00078 18.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) DUF1517 PF07466.6 EME25825.1 - 0.43 9.5 3.4 0.37 9.7 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) SPRR2 PF14820.1 EME25825.1 - 9.7 6.1 11.5 1.5 8.7 5.3 1.8 2 0 0 2 2 2 0 Small proline-rich 2 DNA_pol_B_exo1 PF03104.14 EME25826.1 - 3.1e-24 85.4 0.0 5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 EME25826.1 - 1.5e-06 28.0 0.5 6.8e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EME25826.1 - 0.00012 21.7 0.1 0.00035 20.1 0.0 1.8 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB SAM_2 PF07647.12 EME25828.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Duffy_binding PF05424.6 EME25829.1 - 0.035 13.9 0.1 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Duffy binding domain DUF3783 PF12646.2 EME25829.1 - 0.081 12.6 0.3 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Sua5_yciO_yrdC PF01300.13 EME25830.1 - 3.1e-56 189.4 0.0 4.6e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EME25830.1 - 1.7e-32 112.1 0.0 2.5e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding CRAL_TRIO PF00650.15 EME25831.1 - 2.6e-06 26.9 0.0 9.1e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EME25831.1 - 0.001 18.9 0.0 0.0041 17.0 0.0 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AAA_22 PF13401.1 EME25832.1 - 0.079 13.1 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1654 PF07867.6 EME25834.1 - 0.16 11.3 0.0 0.43 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) ABC2_membrane PF01061.19 EME25836.1 - 6.5e-35 120.2 20.9 6.5e-35 120.2 14.5 2.4 2 1 1 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 EME25836.1 - 1.7e-15 57.5 0.3 3.2e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EME25836.1 - 4.2e-06 26.2 0.4 0.00013 21.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME25836.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME25836.1 - 2.7e-05 23.4 0.1 4.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EME25836.1 - 6.1e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EME25836.1 - 6.9e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EME25836.1 - 9e-05 23.2 0.0 0.0002 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EME25836.1 - 0.00012 22.4 0.3 0.00022 21.6 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME25836.1 - 0.00026 20.4 0.7 0.00052 19.4 0.5 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EME25836.1 - 0.00034 20.9 0.0 0.0071 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EME25836.1 - 0.00053 20.0 1.4 0.0008 19.4 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EME25836.1 - 0.0006 19.9 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain UPF0079 PF02367.12 EME25836.1 - 0.00063 19.3 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EME25836.1 - 0.0016 18.2 0.7 0.003 17.2 0.1 1.8 2 0 0 2 2 1 1 NTPase Arch_ATPase PF01637.13 EME25836.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 EME25836.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME25836.1 - 0.0038 16.9 0.5 0.0086 15.8 0.4 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EME25836.1 - 0.0045 16.4 0.8 0.0079 15.6 0.5 1.4 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.7 EME25836.1 - 0.005 16.5 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EME25836.1 - 0.005 16.4 0.1 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME25836.1 - 0.0051 15.7 0.1 0.0092 14.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain SSB PF00436.20 EME25836.1 - 0.0075 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Single-strand binding protein family RNA_helicase PF00910.17 EME25836.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EME25836.1 - 0.011 15.7 0.1 0.028 14.3 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EME25836.1 - 0.013 14.9 0.4 0.022 14.1 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EME25836.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME25836.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME25836.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EME25836.1 - 0.025 13.2 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Dynamin_N PF00350.18 EME25836.1 - 0.031 14.0 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Dynamin family FeoB_N PF02421.13 EME25836.1 - 0.034 13.4 0.1 0.064 12.5 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SMC_N PF02463.14 EME25836.1 - 0.046 12.9 0.0 0.064 12.4 0.0 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF2075 PF09848.4 EME25836.1 - 0.048 12.6 0.1 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EME25836.1 - 0.049 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EME25836.1 - 0.069 12.6 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EME25836.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 EME25836.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EME25836.1 - 0.14 11.2 0.1 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1772 PF08592.6 EME25837.1 - 0.0026 17.4 1.0 0.0026 17.4 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CRF PF00473.12 EME25840.1 - 0.13 12.4 1.5 0.18 11.9 1.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor family Arf PF00025.16 EME25841.1 - 2.2e-41 141.0 0.1 2.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EME25841.1 - 2.7e-11 42.8 0.3 2e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EME25841.1 - 6.1e-11 41.8 0.0 7.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME25841.1 - 1.5e-10 40.7 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME25841.1 - 1.6e-10 41.4 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME25841.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME25841.1 - 2.3e-09 37.2 0.1 3.4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME25841.1 - 5.5e-06 25.9 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EME25841.1 - 0.00064 19.4 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EME25841.1 - 0.0015 18.6 0.0 0.0063 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME25841.1 - 0.0035 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME25841.1 - 0.0087 16.3 0.1 0.012 15.9 0.1 1.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EME25841.1 - 0.011 15.2 0.2 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 EME25841.1 - 0.011 14.9 0.1 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EME25841.1 - 0.021 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 EME25841.1 - 0.022 13.8 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EME25841.1 - 0.029 14.3 0.1 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EME25841.1 - 0.03 13.5 0.1 0.068 12.4 0.1 1.5 1 1 1 2 2 2 0 Ferrous iron transport protein B DUF2710 PF10921.3 EME25841.1 - 0.076 13.1 0.1 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) AAA_PrkA PF08298.6 EME25841.1 - 0.12 11.0 0.1 0.33 9.5 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain AAA_18 PF13238.1 EME25841.1 - 0.13 12.6 0.3 0.26 11.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EME25841.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PsbM PF05151.7 EME25842.1 - 6.9e-11 41.5 1.1 1.3e-10 40.6 0.7 1.5 1 0 0 1 1 1 1 Photosystem II reaction centre M protein (PsbM) Methyltransf_3 PF01596.12 EME25844.1 - 1.8e-50 170.8 0.0 2.6e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase dNK PF01712.14 EME25844.1 - 2.2e-20 73.0 0.1 4.8e-20 71.9 0.1 1.6 1 1 0 1 1 1 1 Deoxynucleoside kinase Methyltransf_24 PF13578.1 EME25844.1 - 1.4e-17 64.4 0.0 3.1e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thymidylate_kin PF02223.12 EME25844.1 - 1.7e-05 24.2 0.0 6.1e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Thymidylate kinase Methyltransf_26 PF13659.1 EME25844.1 - 7.1e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AAA_18 PF13238.1 EME25844.1 - 0.00028 21.2 0.3 0.0016 18.7 0.0 2.5 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EME25844.1 - 0.0044 16.8 0.0 0.021 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EME25844.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 UPF0020 PF01170.13 EME25844.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PPR PF01535.15 EME25845.1 - 0.007 16.2 0.1 0.048 13.6 0.1 2.5 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 EME25845.1 - 0.086 12.8 0.4 0.23 11.4 0.3 1.7 1 0 0 1 1 1 0 PPR repeat family IBR PF01485.16 EME25846.1 - 0.00017 21.3 17.2 0.006 16.4 1.5 2.6 2 1 0 2 2 2 2 IBR domain Arch_ATPase PF01637.13 EME25850.1 - 0.016 14.9 0.0 0.14 11.8 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Arch_ATPase PF01637.13 EME25852.1 - 0.0025 17.5 0.0 0.025 14.2 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase UPF0640 PF15114.1 EME25855.1 - 0.12 11.9 0.1 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 UCH PF00443.24 EME25856.1 - 6e-24 84.5 0.0 6.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME25856.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TnpB_IS66 PF05717.8 EME25856.1 - 0.032 13.6 0.2 0.59 9.5 0.1 2.2 1 1 0 1 1 1 0 IS66 Orf2 like protein zf-C3HC4_3 PF13920.1 EME25857.1 - 1.1e-06 28.1 8.6 1.1e-06 28.1 6.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME25857.1 - 4.3e-05 23.2 11.8 4.3e-05 23.2 8.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME25857.1 - 0.00014 21.5 13.4 0.00059 19.5 7.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME25857.1 - 0.00052 19.6 10.9 0.00052 19.6 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME25857.1 - 0.00089 19.2 11.1 0.00089 19.2 7.7 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME25857.1 - 0.073 12.6 6.8 0.17 11.4 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EME25857.1 - 1.6 8.2 8.2 4.2 6.9 5.7 1.7 1 0 0 1 1 1 0 P-11 zinc finger Glyco_hydro_38C PF07748.8 EME25858.1 - 9.2e-41 140.0 0.0 1e-40 139.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Ribosomal_L28e PF01778.12 EME25862.1 - 4.1e-29 101.3 0.2 5.2e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Sugar_tr PF00083.19 EME25864.1 - 2.3e-22 79.2 22.4 4.1e-18 65.1 6.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter YjeF_N PF03853.10 EME25865.1 - 1.9e-37 128.4 0.0 2.5e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus RNA_pol_Rpb2_1 PF04563.10 EME25866.1 - 5.7e-52 175.6 0.0 7.6e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit Gemini_AL3 PF01407.12 EME25867.1 - 0.45 9.9 2.9 0.71 9.3 0.4 1.9 1 1 1 2 2 2 0 Geminivirus AL3 protein Arch_ATPase PF01637.13 EME25868.1 - 0.058 13.0 1.1 0.9 9.1 0.0 3.1 2 1 0 2 2 2 0 Archaeal ATPase Arch_ATPase PF01637.13 EME25871.1 - 1.2e-05 25.1 0.1 6.8e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME25871.1 - 0.054 13.6 0.0 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cu_amine_oxid PF01179.15 EME25875.1 - 4e-145 483.6 0.2 6.3e-72 242.5 0.1 2.0 2 0 0 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EME25875.1 - 2.8e-18 65.8 0.0 5.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.17 EME25876.1 - 1.4e-159 531.3 0.0 1.7e-159 531.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME25876.1 - 0.0057 15.9 0.0 0.049 12.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) TCTP PF00838.12 EME25877.1 - 9.6e-25 87.4 0.5 1.1e-24 87.3 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein MARVEL PF01284.18 EME25878.1 - 1e-05 25.3 13.2 1.7e-05 24.7 9.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EME25878.1 - 2.1 7.8 12.2 0.11 12.0 3.6 2.0 1 1 0 2 2 2 0 SUR7/PalI family HMA PF00403.21 EME25879.1 - 1.8e-17 63.2 17.6 1.5e-09 37.8 0.0 5.6 7 0 0 7 7 7 4 Heavy-metal-associated domain DUF3505 PF12013.3 EME25879.1 - 0.098 12.8 5.4 0.22 11.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) HCO3_cotransp PF00955.16 EME25880.1 - 5.3e-36 124.3 7.7 7.7e-36 123.8 5.3 1.2 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.8 EME25880.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Npa1 PF11707.3 EME25880.1 - 0.018 14.0 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal PTS_EIIA_2 PF00359.17 EME25880.1 - 0.033 13.9 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF1654 PF07867.6 EME25881.1 - 0.17 11.2 0.0 0.52 9.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME25883.1 - 0.0027 17.4 0.1 0.024 14.3 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase Hint PF01079.15 EME25884.1 - 8.3e-26 90.5 0.0 2.4e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Hint module VHP PF02209.14 EME25884.1 - 1.4 8.6 4.5 0.69 9.6 0.2 2.6 3 0 0 3 3 3 0 Villin headpiece domain Glyco_transf_34 PF05637.7 EME25885.1 - 3.8e-22 78.9 0.1 3.4e-11 43.0 0.2 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EME25885.1 - 9.8e-05 21.7 0.3 0.00014 21.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 MliC PF09864.4 EME25885.1 - 0.069 12.8 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme TPR_11 PF13414.1 EME25887.1 - 0.00049 19.6 0.0 0.05 13.2 0.0 2.5 1 1 1 2 2 2 2 TPR repeat IncA PF04156.9 EME25887.1 - 0.0035 16.9 3.1 0.0035 16.9 2.2 2.2 2 0 0 2 2 2 1 IncA protein Sec34 PF04136.10 EME25887.1 - 0.02 14.6 4.5 0.11 12.2 0.4 2.3 1 1 1 2 2 2 0 Sec34-like family Y_phosphatase2 PF03162.8 EME25888.1 - 1.4e-41 141.6 0.3 6.1e-41 139.5 0.0 2.0 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EME25888.1 - 0.0013 18.9 0.2 0.0056 16.9 0.0 2.1 2 1 0 2 2 2 1 Tyrosine phosphatase family Spc7 PF08317.6 EME25889.1 - 0.0063 15.2 2.0 0.0066 15.1 1.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein FeoC PF09012.5 EME25889.1 - 0.011 15.3 0.6 0.029 14.0 0.2 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator Dynactin PF12455.3 EME25889.1 - 0.013 14.4 0.3 0.014 14.3 0.2 1.0 1 0 0 1 1 1 0 Dynein associated protein Vps53_N PF04100.7 EME25889.1 - 0.014 14.1 0.8 0.015 14.0 0.5 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF4071 PF13281.1 EME25889.1 - 0.017 13.9 0.5 0.019 13.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF2379 PF09543.5 EME25889.1 - 0.033 14.1 1.4 0.04 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF4533 PF15047.1 EME25889.1 - 0.037 13.4 0.3 0.039 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF3283 PF11686.3 EME25889.1 - 0.038 13.7 0.2 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Cluap1 PF10234.4 EME25889.1 - 0.044 12.9 1.6 0.045 12.9 1.1 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 Pet127 PF08634.5 EME25889.1 - 0.047 12.8 0.1 0.053 12.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet127 FAM86 PF14904.1 EME25889.1 - 0.049 13.3 0.8 0.14 11.9 0.4 1.8 1 1 1 2 2 2 0 Family of unknown function DUF1664 PF07889.7 EME25889.1 - 0.083 12.6 0.4 0.088 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EME25889.1 - 0.15 12.5 1.9 0.18 12.2 1.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EME25889.1 - 0.34 10.7 6.2 0.23 11.2 3.1 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MtN3_slv PF03083.11 EME25890.1 - 2.6e-24 84.8 9.0 2.4e-18 65.7 0.7 2.5 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange COPI_assoc PF08507.5 EME25890.1 - 0.37 10.4 3.6 0.5 10.0 1.4 1.8 1 1 1 2 2 2 0 COPI associated protein DUF4363 PF14276.1 EME25891.1 - 0.056 13.1 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) SAM_1 PF00536.25 EME25893.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Chloroa_b-bind PF00504.16 EME25894.1 - 1.8e-41 141.9 0.0 2.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Sgf11 PF08209.6 EME25895.1 - 6.6e-11 41.3 1.5 1.1e-10 40.6 1.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF4661 PF15576.1 EME25895.1 - 6.2 6.3 7.3 12 5.4 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) HAD_2 PF13419.1 EME25896.1 - 2e-21 77.0 0.1 2.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME25896.1 - 0.0002 20.9 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EME25896.1 - 0.0051 16.4 0.2 0.026 14.1 0.1 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.2 EME25896.1 - 0.0056 16.3 0.1 0.31 10.6 0.0 2.1 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase PF00702.21 EME25896.1 - 0.02 15.3 0.0 0.79 10.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3867 PF12983.2 EME25896.1 - 0.056 13.4 0.1 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DBC1 PF14443.1 EME25898.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 DBC1 Complex1_LYR PF05347.10 EME25899.1 - 5.5e-05 22.8 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME25899.1 - 0.00086 19.4 0.2 0.0016 18.5 0.0 1.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EME25899.1 - 0.0065 16.9 0.1 0.0077 16.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Arch_ATPase PF01637.13 EME25901.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase Hint PF01079.15 EME25902.1 - 2.5e-34 118.3 0.0 3.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Hint module Vint PF14623.1 EME25902.1 - 0.0074 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Glyco_transf_25 PF01755.12 EME25904.1 - 8.1e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Barttin PF15462.1 EME25904.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) IncA PF04156.9 EME25904.1 - 3.5 7.1 8.5 5.9 6.4 5.9 1.3 1 0 0 1 1 1 0 IncA protein zf-C3HC4_2 PF13923.1 EME25905.1 - 0.00097 19.1 12.6 0.022 14.7 6.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RNHCP PF12647.2 EME25905.1 - 0.0068 16.2 1.6 0.022 14.5 1.1 1.8 1 0 0 1 1 1 1 RNHCP domain GcpE PF04551.9 EME25905.1 - 0.016 14.0 0.5 0.13 11.0 0.8 1.9 2 0 0 2 2 2 0 GcpE protein Thioredoxin_8 PF13905.1 EME25905.1 - 0.11 12.6 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like PA PF02225.17 EME25905.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 PA domain zinc-ribbons_6 PF07191.7 EME25905.1 - 2.3 8.0 9.8 10 6.0 6.3 2.4 1 1 1 2 2 2 0 zinc-ribbons CRAL_TRIO PF00650.15 EME25906.1 - 1.7e-06 27.6 0.0 5.1e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EME25906.1 - 0.00081 19.3 0.1 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Cation_ATPase_C PF00689.16 EME25906.1 - 0.42 10.1 5.6 0.92 9.0 3.9 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Aldo_ket_red PF00248.16 EME25907.1 - 6.8e-68 228.5 0.0 7.7e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EME25908.1 - 4.7e-64 215.9 0.0 5.1e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.1 EME25909.1 - 8.9e-12 45.0 0.0 1.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME25909.1 - 5.4e-07 30.0 0.1 1.3e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EME25909.1 - 1.5e-06 28.0 1.6 3.6e-06 26.8 1.1 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 EME25909.1 - 2.8e-05 24.0 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME25909.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2268 PF10026.4 EME25909.1 - 0.088 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) MRP-S22 PF10245.4 EME25909.1 - 0.22 10.8 1.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S22 Fer4_14 PF13394.1 EME25910.1 - 5.3e-14 52.2 1.7 8.2e-13 48.4 1.2 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 EME25910.1 - 5.6e-11 42.8 0.0 7.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EME25910.1 - 2.9e-09 37.1 1.1 1e-08 35.3 0.3 2.1 1 1 0 2 2 2 1 4Fe-4S single cluster domain Gemini_mov PF01708.11 EME25912.1 - 0.14 11.7 0.5 0.26 10.8 0.3 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Arch_ATPase PF01637.13 EME25913.1 - 0.043 13.5 0.0 0.2 11.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase zf-RING_2 PF13639.1 EME25915.1 - 1.4e-09 37.5 14.2 2.6e-09 36.7 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME25915.1 - 9.4e-08 31.6 13.4 1.7e-07 30.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME25915.1 - 1.3e-06 28.0 15.3 2.3e-06 27.2 10.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME25915.1 - 5.9e-06 26.2 15.3 1.2e-05 25.2 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME25915.1 - 6.7e-05 22.4 14.1 0.00012 21.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME25915.1 - 0.0003 20.8 7.5 0.00064 19.7 5.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EME25915.1 - 0.00031 20.3 5.3 0.0009 18.9 3.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EME25915.1 - 0.004 16.7 13.0 0.007 15.9 9.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 EME25915.1 - 0.026 14.3 13.2 0.076 12.9 9.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger PXT1 PF15214.1 EME25915.1 - 0.1 12.8 1.1 0.22 11.7 0.3 1.9 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 zf-RING_6 PF14835.1 EME25915.1 - 0.18 11.6 6.5 0.36 10.6 4.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EME25915.1 - 0.94 9.0 9.5 7.4 6.2 6.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UPF0547 PF10571.4 EME25915.1 - 7.5 6.3 12.9 1.6 8.4 0.7 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IBR PF01485.16 EME25915.1 - 8.4 6.3 13.0 32 4.4 9.0 2.0 1 1 0 1 1 1 0 IBR domain Rtf2 PF04641.7 EME25915.1 - 9.3 5.3 8.6 9.6 5.3 5.0 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger Uma2 PF05685.7 EME25916.1 - 0.062 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease DrsE PF02635.10 EME25916.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF-like family PP_M1 PF03012.9 EME25916.1 - 0.12 11.7 1.2 0.17 11.2 0.9 1.1 1 0 0 1 1 1 0 Phosphoprotein tRNA-synt_1e PF01406.14 EME25917.1 - 4e-97 324.9 0.0 5.8e-97 324.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EME25917.1 - 4e-10 38.9 0.0 0.00031 19.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) AAA_22 PF13401.1 EME25918.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain MIP PF00230.15 EME25921.1 - 1e-47 162.5 6.7 1.3e-47 162.1 4.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein RmlD_sub_bind PF04321.12 EME25922.1 - 2.3e-33 115.3 0.0 3.1e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EME25922.1 - 9.4e-15 54.6 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME25922.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME25922.1 - 0.0097 14.8 0.0 0.033 13.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein THUMP PF02926.12 EME25923.1 - 1.5e-09 37.8 1.7 3e-09 36.9 1.2 1.5 1 0 0 1 1 1 1 THUMP domain TCTP PF00838.12 EME25925.1 - 1.4e-38 132.4 0.6 1.6e-38 132.2 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PerC PF06069.6 EME25926.1 - 0.14 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 PerC transcriptional activator XRN_N PF03159.13 EME25927.1 - 3.8e-101 337.4 0.0 3.8e-101 337.4 0.0 2.3 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus POR_N PF01855.14 EME25928.1 - 0.024 14.1 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PAD_porph PF04371.10 EME25929.1 - 2e-124 414.9 0.0 2.2e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase CN_hydrolase PF00795.17 EME25930.1 - 1.2e-06 27.9 0.0 1.5e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase dCMP_cyt_deam_1 PF00383.17 EME25930.1 - 0.74 9.4 3.4 1.2 8.8 2.3 1.4 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region CN_hydrolase PF00795.17 EME25931.1 - 6.4e-08 32.1 0.0 7.8e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Hint PF01079.15 EME25932.1 - 2.3e-33 115.2 0.0 4.3e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 EME25932.1 - 3.7e-07 30.1 0.0 4.6e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 Hint domain MitoNEET_N PF10660.4 EME25933.1 - 0.085 12.7 0.8 2.4 8.0 0.1 2.1 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus adh_short PF00106.20 EME25935.1 - 8.5e-17 61.5 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME25935.1 - 7.3e-08 32.2 0.0 9.7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME25935.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME25935.1 - 0.00028 20.4 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME25935.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EME25935.1 - 0.005 15.9 0.0 0.012 14.6 0.1 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EME25935.1 - 0.025 14.4 0.3 0.037 13.8 0.2 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EME25935.1 - 0.031 14.0 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EME25935.1 - 0.06 12.2 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 EME25936.1 - 1.4e-34 116.7 4.1 3.5e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40 PF00400.27 EME25937.1 - 1.3e-34 116.8 4.1 3.4e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat peroxidase PF00141.18 EME25938.1 - 1.1e-25 90.5 0.0 2.5e-25 89.3 0.0 1.6 1 1 0 1 1 1 1 Peroxidase GidB PF02527.10 EME25940.1 - 3.8e-43 146.7 0.0 4.8e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EME25940.1 - 2.6e-10 40.0 0.0 4.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME25940.1 - 3.9e-06 26.3 0.0 6.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME25940.1 - 0.00039 20.8 0.0 0.0052 17.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME25940.1 - 0.00073 20.0 0.0 0.003 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EME25940.1 - 0.00077 18.9 0.1 0.0022 17.5 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 EME25940.1 - 0.0059 17.0 0.0 0.015 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME25940.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 EME25940.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain IBP39 PF11422.3 EME25940.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Initiator binding protein 39 kDa RCC1 PF00415.13 EME25942.1 - 4e-60 199.8 17.3 1.3e-09 38.1 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME25942.1 - 1.3e-33 113.8 38.0 4e-07 29.4 2.9 6.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EME25942.1 - 0.046 13.1 4.9 7.5 6.1 0.0 4.7 5 0 0 5 5 5 0 Putative carbohydrate binding domain SBBP PF06739.6 EME25942.1 - 0.24 11.2 1.5 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Beta-propeller repeat Lantibiotic_a PF14867.1 EME25947.1 - 0.31 10.2 3.2 0.26 10.5 0.4 2.1 2 0 0 2 2 2 0 Lantibiotic alpha GTP_EFTU PF00009.22 EME25950.1 - 2e-26 92.5 0.0 3.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME25950.1 - 1.1e-06 28.5 0.0 5.7e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME25950.1 - 0.019 15.4 0.0 0.073 13.5 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Peptidase_S3 PF00944.14 EME25950.1 - 0.057 12.8 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Alphavirus core protein MobB PF03205.9 EME25950.1 - 0.17 11.6 0.9 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EME25950.1 - 2.1 8.6 0.0 2.1 8.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EME25950.1 - 2.5 7.8 5.7 1.3 8.7 0.0 2.9 2 2 1 3 3 3 0 Dynamin family AAA PF00004.24 EME25951.1 - 9.8e-45 151.9 0.0 2.5e-37 128.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME25951.1 - 2.4e-08 34.1 0.0 2.7e-05 24.2 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME25951.1 - 4e-08 33.4 0.0 0.00036 20.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME25951.1 - 1.4e-07 31.5 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME25951.1 - 5.9e-06 27.0 0.0 0.00034 21.4 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EME25951.1 - 0.00022 21.1 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EME25951.1 - 0.0004 20.0 0.0 0.00081 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME25951.1 - 0.00046 20.1 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EME25951.1 - 0.0014 18.9 0.0 0.015 15.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EME25951.1 - 0.0026 16.8 0.0 0.0064 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EME25951.1 - 0.0045 16.7 0.0 0.022 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME25951.1 - 0.006 15.9 0.0 0.031 13.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EME25951.1 - 0.0095 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EME25951.1 - 0.01 15.9 0.0 0.1 12.7 0.0 2.6 3 0 0 3 3 3 0 RNA helicase Mg_chelatase PF01078.16 EME25951.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EME25951.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EME25951.1 - 0.015 14.1 0.0 0.04 12.8 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EME25951.1 - 0.033 13.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EME25951.1 - 0.041 13.5 0.0 0.24 11.0 0.0 2.4 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.8 EME25951.1 - 0.05 12.3 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EME25951.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EME25951.1 - 0.13 12.1 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.21 EME25951.1 - 0.14 11.6 0.0 2 7.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.4 EME25951.1 - 0.16 11.4 0.0 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EME25951.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RWP-RK PF02042.10 EME25952.1 - 1.8e-20 72.5 0.2 3.5e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 RWP-RK domain Osmo_CC PF08946.5 EME25952.1 - 0.15 12.0 2.3 0.33 11.0 1.3 1.8 1 1 0 1 1 1 0 Osmosensory transporter coiled coil CYSTM PF12734.2 EME25953.1 - 0.28 11.2 34.3 1.4e+02 2.6 23.7 3.3 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Imm27 PF15573.1 EME25955.1 - 0.038 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 27 Arb1 PF09692.5 EME25955.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF4042 PF13251.1 EME25960.1 - 0.00036 20.0 0.5 0.004 16.6 0.4 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4042) Transposase_28 PF04195.7 EME25960.1 - 0.0071 15.6 0.0 0.02 14.1 0.1 1.7 2 0 0 2 2 2 1 Putative gypsy type transposon Mg_chelatase PF01078.16 EME25960.1 - 0.15 11.2 0.2 0.91 8.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3760 PF12586.3 EME25960.1 - 3.2 7.6 5.2 1.2 8.9 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) COX7C PF02935.11 EME25961.1 - 0.075 12.8 4.1 0.13 12.0 2.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc V-SNARE_C PF12352.3 EME25962.1 - 5e-14 52.1 2.8 5e-14 52.1 1.9 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EME25962.1 - 0.063 12.9 0.8 0.25 11.0 0.0 2.1 1 1 1 2 2 2 0 Sec20 ATP_synt_I PF03899.10 EME25963.1 - 9.8e-09 35.2 3.7 1.6e-08 34.6 2.6 1.3 1 0 0 1 1 1 1 ATP synthase I chain AtpR PF12966.2 EME25963.1 - 0.00015 21.8 1.3 0.00033 20.7 0.9 1.5 1 0 0 1 1 1 1 N-ATPase, AtpR subunit CYSTM PF12734.2 EME25964.1 - 0.28 11.2 34.3 1.4e+02 2.6 23.7 3.3 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance RWP-RK PF02042.10 EME25965.1 - 1.1e-20 73.1 0.2 2.3e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain DUF4428 PF14471.1 EME25965.1 - 0.057 13.1 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Osmo_CC PF08946.5 EME25965.1 - 0.1 12.6 2.3 0.23 11.4 1.4 1.9 1 1 0 1 1 1 0 Osmosensory transporter coiled coil DUF711 PF05167.7 EME25966.1 - 0.002 16.9 0.6 0.0029 16.3 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) Baculo_PEP_C PF04513.7 EME25966.1 - 0.01 15.6 7.6 0.01 15.6 5.3 2.4 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_repr_REX1B PF14966.1 EME25966.1 - 0.62 10.4 3.2 12 6.3 0.1 2.5 1 1 1 2 2 2 0 DNA repair REX1-B Fib_alpha PF08702.5 EME25966.1 - 6.3 6.9 6.3 2.8 8.0 2.5 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AvrL567-A PF11529.3 EME25967.1 - 0.12 12.3 4.4 15 5.5 0.0 3.9 2 2 2 4 4 4 0 Melampsora lini avirulence protein AvrL567-A GTP_EFTU_D3 PF03143.12 EME25968.1 - 4.9e-08 33.0 0.1 7.5e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME25968.1 - 0.00015 21.7 0.1 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 NAD_binding_8 PF13450.1 EME25969.1 - 4.5e-12 45.8 0.1 3.5e-10 39.7 0.1 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME25969.1 - 2.4e-08 33.5 0.8 3.8e-05 22.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EME25969.1 - 7.1e-08 31.7 0.2 8.2e-05 21.6 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME25969.1 - 0.00063 20.0 0.2 0.37 11.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME25969.1 - 0.00096 17.7 0.3 0.0069 14.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EME25969.1 - 0.0014 17.8 0.2 0.04 12.9 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EME25969.1 - 0.0017 17.4 0.2 0.0033 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EME25969.1 - 0.0025 17.6 0.1 0.62 9.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EME25969.1 - 0.021 13.7 0.7 0.031 13.1 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EME25969.1 - 0.031 13.1 0.4 0.045 12.5 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME25969.1 - 0.042 13.7 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME25969.1 - 0.16 11.9 1.0 0.43 10.6 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_11 PF13414.1 EME25970.1 - 2.2e-06 27.2 0.4 2.9e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 EME25970.1 - 2.6e-06 27.2 0.2 0.00026 20.8 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME25970.1 - 2.7e-06 26.7 0.2 0.31 10.9 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME25970.1 - 1.6e-05 24.4 0.2 1.3 9.0 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME25970.1 - 0.0061 16.1 0.2 16 5.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RecU PF03838.9 EME25970.1 - 0.025 14.1 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 Recombination protein U TPR_17 PF13431.1 EME25970.1 - 0.057 13.6 0.0 15 6.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MvaI_BcnI PF15515.1 EME25971.1 - 0.085 12.8 0.1 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Peptidase_S24 PF00717.18 EME25972.1 - 1.5e-05 24.5 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EME25972.1 - 0.0032 16.9 0.0 0.49 9.9 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Glycolytic PF00274.14 EME25973.1 - 7e-166 550.8 0.0 8.1e-166 550.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L4 PF00573.17 EME25974.1 - 2.3e-49 167.4 0.0 2.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Arch_ATPase PF01637.13 EME25977.1 - 0.0017 18.0 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase Arch_ATPase PF01637.13 EME25979.1 - 0.00035 20.3 0.4 0.0017 18.1 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase Arch_ATPase PF01637.13 EME25984.1 - 0.004 16.8 0.1 0.035 13.7 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME25984.1 - 0.2 11.8 0.2 3.6 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EME25985.1 - 0.00045 19.9 0.0 0.0016 18.1 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase DUF1654 PF07867.6 EME25985.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME25987.1 - 0.015 14.9 0.1 0.17 11.5 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase Arf PF00025.16 EME25990.1 - 2.2e-41 141.0 0.1 2.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EME25990.1 - 2.6e-11 42.8 0.3 1.9e-05 23.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EME25990.1 - 5.9e-11 41.9 0.0 7.3e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME25990.1 - 1.5e-10 40.7 0.0 2.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME25990.1 - 1.6e-10 41.5 0.0 2.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME25990.1 - 1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME25990.1 - 2.2e-09 37.2 0.1 3.3e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME25990.1 - 5.3e-06 25.9 0.0 1.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EME25990.1 - 0.00062 19.4 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EME25990.1 - 0.0015 18.6 0.0 0.0062 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME25990.1 - 0.0034 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME25990.1 - 0.0088 16.3 0.1 0.014 15.6 0.1 1.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EME25990.1 - 0.01 15.2 0.2 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 EME25990.1 - 0.011 14.9 0.1 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EME25990.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 EME25990.1 - 0.022 13.8 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EME25990.1 - 0.028 14.3 0.1 0.048 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EME25990.1 - 0.029 13.6 0.1 0.067 12.4 0.1 1.5 1 1 1 2 2 2 0 Ferrous iron transport protein B DUF2710 PF10921.3 EME25990.1 - 0.075 13.1 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) AAA_18 PF13238.1 EME25990.1 - 0.12 12.6 0.2 0.26 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 EME25990.1 - 0.13 10.8 0.1 0.37 9.4 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain ABC_tran PF00005.22 EME25990.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DS PF01916.12 EME25991.1 - 1e-126 422.1 0.0 1.2e-126 421.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EME25991.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Tim17 PF02466.14 EME25992.1 - 2.7e-06 27.4 1.5 4.3e-06 26.7 1.1 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EME25992.1 - 0.035 14.2 0.2 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF3792 PF12670.2 EME25992.1 - 0.062 13.1 4.7 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) ATP-synt_C PF00137.16 EME25992.1 - 0.099 12.5 0.5 0.099 12.5 0.4 1.7 2 0 0 2 2 2 0 ATP synthase subunit C ATP-synt_E PF05680.7 EME25992.1 - 0.18 11.7 0.4 13 5.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase E chain TPR_19 PF14559.1 EME25993.1 - 2.8e-06 27.5 7.5 0.4 11.0 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME25993.1 - 0.0003 20.4 2.3 24 5.1 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME25993.1 - 0.00051 20.4 8.5 4.1 8.3 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME25993.1 - 0.002 17.6 8.0 6.5 6.5 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME25993.1 - 0.0047 17.5 4.9 71 4.2 0.0 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EME25993.1 - 0.066 13.6 2.1 12 6.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME25993.1 - 0.072 12.9 1.8 1.2 9.0 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME25993.1 - 0.13 12.7 5.0 23 5.7 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1654 PF07867.6 EME25995.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME25997.1 - 0.001 18.8 0.0 0.016 14.8 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase Sugar_tr PF00083.19 EME25998.1 - 2.5e-18 65.9 8.0 3.1e-18 65.5 5.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME25998.1 - 7.5e-08 31.4 10.3 1.4e-07 30.6 7.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME25998.1 - 4.8e-06 25.2 6.3 6.8e-06 24.7 3.1 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein Methyltransf_16 PF10294.4 EME25999.1 - 1.1e-25 90.0 0.1 1.5e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME25999.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EME25999.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EME26000.1 - 1.1e-25 90.0 0.1 1.5e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME26000.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EME26000.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Membralin PF09746.4 EME26001.1 - 1.6e-07 30.7 12.3 1.5e-06 27.5 4.7 2.7 1 1 0 2 2 2 2 Tumour-associated protein INTS5_N PF14837.1 EME26001.1 - 0.0075 15.6 2.4 0.2 11.0 0.7 2.3 2 0 0 2 2 2 2 Integrator complex subunit 5 N-terminus TP_methylase PF00590.15 EME26002.1 - 8.4e-38 130.1 0.0 9.9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribonuc_red_lgC PF02867.10 EME26003.1 - 6.3e-140 467.2 0.0 7.9e-139 463.6 0.0 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EME26003.1 - 2.6e-13 49.5 0.0 5.9e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain 2C_adapt PF08793.5 EME26004.1 - 3.9e-10 39.4 1.3 0.0078 16.0 0.0 3.5 3 0 0 3 3 3 3 2-cysteine adaptor domain GTP_EFTU PF00009.22 EME26006.1 - 6.6e-50 169.1 0.0 9.9e-50 168.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EME26006.1 - 2.8e-17 62.3 0.0 5.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EME26006.1 - 1.9e-12 46.8 0.0 4.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EME26006.1 - 2.3e-05 23.9 0.0 8.8e-05 22.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EME26006.1 - 0.00083 19.4 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 CDC50 PF03381.10 EME26006.1 - 0.21 10.7 0.9 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 LEM3 (ligand-effect modulator 3) family / CDC50 family HI0933_like PF03486.9 EME26007.1 - 6.1e-95 318.0 0.0 7e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EME26007.1 - 9.7e-06 24.6 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EME26007.1 - 0.04 12.8 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME26007.1 - 0.043 12.6 0.1 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EME26007.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME26007.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EME26007.1 - 0.18 10.8 0.9 0.27 10.2 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pribosyltran PF00156.22 EME26010.1 - 1.8e-09 37.3 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Gemini_mov PF01708.11 EME26013.1 - 0.14 11.7 0.5 0.26 10.8 0.3 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein LMWPc PF01451.16 EME26015.1 - 3.7e-33 114.7 0.0 4.4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Arch_ATPase PF01637.13 EME26016.1 - 0.0037 16.9 0.0 0.015 15.0 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase CLTH PF10607.4 EME26018.1 - 5.9e-34 116.8 0.2 7.2e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain CLTH PF10607.4 EME26019.1 - 6.1e-34 116.7 0.2 7.5e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40 PF00400.27 EME26020.1 - 6.9e-53 174.7 23.9 9.3e-11 41.1 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat CLTH PF10607.4 EME26020.1 - 1.9e-05 24.4 0.4 3.1e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PQQ_3 PF13570.1 EME26020.1 - 0.00013 22.1 1.7 2.8 8.3 0.0 3.8 3 1 1 4 4 4 2 PQQ-like domain LisH PF08513.6 EME26020.1 - 0.02 14.6 0.2 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 LisH WD40 PF00400.27 EME26021.1 - 6.2e-53 174.9 23.9 9.2e-11 41.2 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat CLTH PF10607.4 EME26021.1 - 1.8e-05 24.4 0.4 3e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PQQ_3 PF13570.1 EME26021.1 - 0.00012 22.1 1.7 2.8 8.3 0.0 3.8 3 1 1 4 4 4 2 PQQ-like domain LisH PF08513.6 EME26021.1 - 0.019 14.6 0.2 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 LisH Myb_DNA-binding PF00249.26 EME26022.1 - 9.7e-15 54.3 0.3 9.7e-15 54.3 0.2 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME26022.1 - 0.00028 20.9 0.2 0.0007 19.6 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Histone PF00125.19 EME26023.1 - 8.5e-27 93.0 0.0 1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME26023.1 - 3.2e-05 23.9 0.0 4.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.6 EME26023.1 - 0.07 13.0 0.1 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.19 EME26024.1 - 2.1e-24 85.4 0.3 3.6e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME26024.1 - 4.1e-07 29.9 1.5 4.3e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EME26024.1 - 0.00046 20.4 0.0 0.00081 19.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DALR_1 PF05746.10 EME26025.1 - 5.4e-30 103.8 0.1 9.2e-30 103.0 0.1 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.14 EME26025.1 - 2.7e-17 62.6 0.0 3.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA_int_end_N2 PF12928.2 EME26025.1 - 0.16 11.4 1.2 0.35 10.3 0.8 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Aldedh PF00171.17 EME26030.1 - 4.2e-73 246.2 0.0 5.2e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF31 PF01732.11 EME26030.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Fe-S_biosyn PF01521.15 EME26031.1 - 9.1e-18 64.2 0.4 1e-17 64.0 0.3 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Tic22 PF04278.7 EME26032.1 - 0.0084 15.4 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Tic22-like family Mg_chelatase PF01078.16 EME26033.1 - 2.2e-11 43.3 0.1 1.8e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME26033.1 - 3.2e-07 30.1 0.0 0.0025 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.18 EME26033.1 - 8.7e-06 24.7 0.6 0.09 11.5 0.0 3.1 2 2 0 2 2 2 2 MCM2/3/5 family Sigma54_activat PF00158.21 EME26033.1 - 2.5e-05 23.8 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 EME26033.1 - 0.00018 21.6 1.5 0.00091 19.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME26033.1 - 0.00024 21.1 0.1 0.0015 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EME26033.1 - 0.0012 19.0 0.1 0.026 14.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EME26033.1 - 0.0021 18.3 0.3 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EME26033.1 - 0.0031 17.0 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 EME26033.1 - 0.0038 16.1 0.0 0.0089 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EME26033.1 - 0.0065 16.7 3.7 0.0075 16.5 0.0 2.5 2 2 0 2 2 2 1 AAA domain Miro PF08477.8 EME26033.1 - 0.01 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 EME26033.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EME26033.1 - 0.026 15.3 3.0 0.072 13.9 0.1 2.5 1 1 0 2 2 2 0 AAA domain MobB PF03205.9 EME26033.1 - 0.072 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EME26033.1 - 0.075 12.9 1.5 0.35 10.7 0.0 2.7 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME26033.1 - 0.097 12.9 6.2 2.6 8.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME26033.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME26033.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME26033.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hexapep PF00132.19 EME26034.1 - 3.1e-21 73.8 30.1 3e-07 29.6 4.5 5.5 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.1 EME26034.1 - 8.3e-19 67.6 0.1 1.4e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.1 EME26034.1 - 4.1 7.0 18.3 1.4 8.5 2.5 5.2 4 2 2 6 6 6 0 Hexapeptide repeat of succinyl-transferase Arch_ATPase PF01637.13 EME26035.1 - 0.027 14.1 0.0 0.083 12.5 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase FAD_binding_1 PF00667.15 EME26036.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain MtN3_slv PF03083.11 EME26037.1 - 5.1e-28 96.7 11.4 3.1e-18 65.4 0.7 2.5 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange COPI_assoc PF08507.5 EME26037.1 - 0.34 10.6 4.3 0.49 10.0 1.8 2.0 1 1 1 2 2 2 0 COPI associated protein MMR_HSR1 PF01926.18 EME26038.1 - 1.2e-08 34.8 0.0 6e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EME26038.1 - 2.2e-05 23.6 0.1 6.7e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME26038.1 - 0.0018 17.7 0.1 0.023 14.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EME26038.1 - 0.0037 16.7 0.1 1.2 8.5 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EME26038.1 - 0.0087 15.3 0.3 0.96 8.7 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.16 EME26038.1 - 0.01 15.0 0.1 2 7.6 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EME26038.1 - 0.021 15.2 0.0 0.077 13.4 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EME26038.1 - 0.075 12.7 0.5 0.44 10.1 0.1 2.2 3 0 0 3 3 3 0 Archaeal ATPase Dynamin_N PF00350.18 EME26038.1 - 0.25 11.1 4.3 5.5 6.7 1.5 2.7 2 1 0 2 2 2 0 Dynamin family Fe-S_biosyn PF01521.15 EME26039.1 - 5.6e-17 61.6 0.0 6.4e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis TPR_11 PF13414.1 EME26040.1 - 2.2e-25 88.1 18.6 5.9e-17 61.0 5.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME26040.1 - 3.6e-14 51.6 16.8 1.2e-05 24.7 2.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME26040.1 - 7.9e-11 41.0 20.8 0.00027 20.6 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME26040.1 - 4.5e-06 27.1 9.4 7e-05 23.3 3.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME26040.1 - 2.6e-05 24.0 11.7 0.0007 19.4 4.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME26040.1 - 4.7e-05 22.8 7.9 0.51 10.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EME26040.1 - 0.00012 22.0 10.6 0.00038 20.5 7.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME26040.1 - 0.00013 22.2 1.7 0.00027 21.2 0.8 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME26040.1 - 0.0013 18.4 4.8 0.079 12.8 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME26040.1 - 0.0021 17.7 9.5 0.49 10.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EME26040.1 - 0.0057 15.8 3.8 0.011 14.9 1.7 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit Fis1_TPR_C PF14853.1 EME26040.1 - 0.007 16.2 6.5 1.8 8.5 0.2 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EME26040.1 - 0.018 15.6 3.5 14 6.6 0.7 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 EME26040.1 - 0.021 14.6 6.0 0.48 10.2 3.6 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EME26040.1 - 0.046 14.2 8.8 0.25 11.8 0.8 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat A2M_N PF01835.14 EME26040.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 MG2 domain DUF4102 PF13356.1 EME26040.1 - 0.16 11.8 0.9 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) MIT PF04212.13 EME26040.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.7 2 1 0 2 2 1 0 MIT (microtubule interacting and transport) domain TPM PF04536.9 EME26040.1 - 0.33 10.8 3.1 10 6.0 0.0 3.1 2 1 2 4 4 4 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase TPR_17 PF13431.1 EME26040.1 - 0.64 10.3 7.6 0.56 10.5 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EME26040.1 - 0.82 9.9 9.5 0.22 11.7 2.1 2.7 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TMA7 PF09072.5 EME26040.1 - 0.98 9.9 3.8 1 9.9 0.6 2.3 2 0 0 2 2 2 0 Translation machinery associated TMA7 TPR_10 PF13374.1 EME26040.1 - 1 9.3 5.0 16 5.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EME26040.1 - 4.5 6.5 7.5 8.6 5.7 0.1 3.9 4 1 0 4 4 4 0 SHNi-TPR Sugar_tr PF00083.19 EME26041.1 - 2.4e-63 214.2 11.9 2.8e-63 214.0 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26041.1 - 1e-18 67.2 14.7 1.4e-18 66.7 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME26041.1 - 7.1e-06 24.6 11.4 0.0073 14.7 0.1 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3040 PF11239.3 EME26041.1 - 0.039 14.0 0.0 0.2 11.7 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MFS_3 PF05977.8 EME26041.1 - 0.3 9.1 12.8 0.32 9.0 8.2 1.4 1 1 0 1 1 1 0 Transmembrane secretion effector SNN_transmemb PF09049.5 EME26041.1 - 3.8 7.2 7.9 0.32 10.7 1.2 2.4 2 0 0 2 2 2 0 Stannin transmembrane IPPT PF01715.12 EME26042.1 - 6e-63 212.2 0.0 8.6e-63 211.6 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 EME26042.1 - 2.9e-10 39.7 0.0 1.2e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EME26042.1 - 2.8e-09 37.8 1.4 7.7e-08 33.1 1.0 2.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME26042.1 - 1.4e-05 24.3 0.0 0.00049 19.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EME26042.1 - 0.00013 22.2 0.3 0.00043 20.6 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 EME26042.1 - 0.00035 20.4 0.6 0.023 14.5 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EME26042.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME26042.1 - 0.012 15.6 0.0 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PPV_E1_C PF00519.12 EME26042.1 - 0.016 13.8 0.0 0.036 12.6 0.0 1.5 1 0 0 1 1 1 0 Papillomavirus helicase ResIII PF04851.10 EME26042.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.18 EME26042.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EME26042.1 - 0.029 14.6 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EME26042.1 - 0.045 13.6 0.1 0.51 10.2 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.9 EME26042.1 - 0.047 13.4 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EME26042.1 - 0.053 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 EME26042.1 - 0.063 11.9 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 EME26042.1 - 0.065 12.7 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 EME26042.1 - 0.078 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME26042.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EME26042.1 - 0.15 10.9 0.1 0.33 9.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EME26042.1 - 0.16 11.6 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IPPT PF01715.12 EME26043.1 - 4.9e-63 212.5 0.0 6.7e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 EME26043.1 - 2.3e-10 40.0 0.0 1.1e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EME26043.1 - 2.1e-09 38.2 1.3 5.2e-08 33.7 0.7 2.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME26043.1 - 1.2e-05 24.4 0.0 0.00042 19.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EME26043.1 - 0.00013 22.2 0.3 0.00037 20.7 0.0 2.0 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 EME26043.1 - 0.00028 20.7 0.6 0.02 14.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EME26043.1 - 0.0028 17.7 0.0 0.0087 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME26043.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.12 EME26043.1 - 0.017 13.7 0.2 0.033 12.8 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase ResIII PF04851.10 EME26043.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit CbiA PF01656.18 EME26043.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SKI PF01202.17 EME26043.1 - 0.037 13.9 0.1 0.43 10.4 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 EME26043.1 - 0.041 14.2 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EME26043.1 - 0.042 13.5 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EME26043.1 - 0.05 13.7 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PRK PF00485.13 EME26043.1 - 0.056 12.9 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 EME26043.1 - 0.062 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EME26043.1 - 0.072 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME26043.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME26043.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EME26043.1 - 0.15 10.9 0.1 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_11 PF08241.7 EME26044.1 - 2.2e-20 72.9 0.0 3.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME26044.1 - 1.9e-15 56.6 0.0 1.1e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME26044.1 - 1.9e-14 53.8 0.0 5.1e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26044.1 - 1.7e-13 50.8 0.0 3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26044.1 - 1.7e-12 47.1 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26044.1 - 4.9e-11 42.6 0.0 8.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26044.1 - 2e-09 37.9 0.0 3.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26044.1 - 6.8e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME26044.1 - 4.3e-06 26.2 0.0 8.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EME26044.1 - 0.0083 15.1 0.0 0.067 12.2 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EME26044.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3683 PF12447.3 EME26044.1 - 0.012 15.4 0.1 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Amidohydro_2 PF04909.9 EME26044.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Methyltransf_2 PF00891.13 EME26044.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase TPMT PF05724.6 EME26044.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FG-GAP_2 PF14312.1 EME26048.1 - 1.5e-09 37.6 3.3 0.15 12.1 0.0 6.0 6 0 0 6 6 6 4 FG-GAP repeat Ribosomal_S8e PF01201.17 EME26049.1 - 2.9e-51 173.0 1.4 4e-51 172.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e bZIP_2 PF07716.10 EME26050.1 - 0.0063 16.3 16.3 0.0063 16.3 11.3 2.9 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EME26050.1 - 0.012 15.5 14.2 0.012 15.5 9.8 2.2 2 1 1 3 3 2 0 bZIP transcription factor bZIP_Maf PF03131.12 EME26050.1 - 0.02 15.1 14.6 0.02 15.1 10.1 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Phage_GP20 PF06810.6 EME26050.1 - 0.12 11.8 5.0 0.31 10.4 3.4 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 AAA_23 PF13476.1 EME26050.1 - 0.28 11.4 6.1 0.34 11.2 4.2 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_N PF10481.4 EME26050.1 - 0.3 10.3 13.0 0.018 14.3 4.3 1.9 1 1 1 2 2 2 0 Cenp-F N-terminal domain Jnk-SapK_ap_N PF09744.4 EME26050.1 - 0.42 10.5 10.1 0.75 9.7 7.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.17 EME26050.1 - 0.99 9.4 10.6 2.7 8.0 7.3 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain H-kinase_dim PF02895.9 EME26050.1 - 1 9.7 4.5 6.8 7.1 3.1 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DivIVA PF05103.8 EME26050.1 - 1.1 9.3 11.5 0.28 11.2 1.6 2.9 2 1 1 3 3 3 0 DivIVA protein DUF342 PF03961.8 EME26050.1 - 5.8 5.2 9.7 1.9 6.8 5.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EME26050.1 - 6.7 5.6 17.0 0.1 11.6 6.8 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Ead_Ea22 PF13935.1 EME26050.1 - 8.2 6.7 9.5 0.45 10.8 1.9 2.3 2 2 0 2 2 2 0 Ead/Ea22-like protein UAA PF08449.6 EME26051.1 - 1e-73 247.9 26.9 1.2e-73 247.7 18.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME26051.1 - 3.3e-10 40.0 28.7 2.1e-07 31.0 4.1 3.3 2 2 2 4 4 4 2 EamA-like transporter family DUF3099 PF11298.3 EME26051.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) TPT PF03151.11 EME26051.1 - 0.25 10.9 27.2 0.13 11.9 7.9 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family Dexa_ind PF15198.1 EME26051.1 - 2 8.3 7.1 1.8 8.5 0.1 3.4 3 0 0 3 3 3 0 Dexamethasone-induced Thioredoxin PF00085.15 EME26052.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EME26052.1 - 0.045 13.7 0.1 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Ribosomal_L18e PF00828.14 EME26053.1 - 1.7e-21 76.9 3.0 2.7e-21 76.2 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aminotran_3 PF00202.16 EME26054.1 - 3.3e-105 351.6 0.0 4.1e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SPOUT_MTase PF02590.12 EME26055.1 - 2.6e-24 85.6 0.1 4.4e-24 84.9 0.0 1.4 1 1 1 2 2 2 1 Predicted SPOUT methyltransferase Ald_Xan_dh_C2 PF02738.13 EME26060.1 - 3.8e-107 358.8 0.2 7.1e-107 357.9 0.0 1.4 2 0 0 2 2 2 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EME26060.1 - 1.4e-38 132.0 0.0 2.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EME26060.1 - 3.9e-29 100.9 0.0 2e-28 98.6 0.0 2.2 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EME26060.1 - 1.6e-26 91.9 0.0 3.7e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 EME26060.1 - 1.4e-20 73.0 0.0 3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 EME26060.1 - 0.00056 19.6 3.0 0.0007 19.2 1.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_M20 PF01546.23 EME26061.1 - 1.7e-17 63.5 0.0 3.3e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME26061.1 - 9.1e-08 31.8 0.0 3.1e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EME26061.1 - 0.00027 20.7 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF4084 PF13321.1 EME26064.1 - 0.019 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) PHD PF00628.24 EME26065.1 - 2.1e-10 40.0 7.2 2.1e-10 40.0 5.0 2.5 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EME26065.1 - 0.00048 19.3 2.8 0.0013 18.0 1.9 1.8 1 0 0 1 1 1 1 PHD-finger DNase-RNase PF02577.9 EME26067.1 - 1.1e-11 44.1 0.0 1.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Bifunctional nuclease Arch_ATPase PF01637.13 EME26068.1 - 6.3e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase Arch_ATPase PF01637.13 EME26071.1 - 0.0055 16.4 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase Sugar_tr PF00083.19 EME26073.1 - 1.1e-74 251.6 14.2 1.3e-74 251.4 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26073.1 - 4.3e-09 35.5 41.1 8.4e-08 31.3 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EME26074.1 - 2.9e-49 167.5 0.0 3.6e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26074.1 - 8e-37 126.7 0.0 1.1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26074.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME26074.1 - 0.009 15.3 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Fructosamin_kin PF03881.9 EME26074.1 - 0.052 12.5 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase Kdo PF06293.9 EME26074.1 - 0.057 12.4 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME26074.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family IMS PF00817.15 EME26075.1 - 1.4e-46 157.9 1.2 3.8e-46 156.5 0.0 2.2 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 EME26075.1 - 5.6e-14 52.1 0.3 1.2e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EME26075.1 - 2.1e-08 33.7 0.1 7.3e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif PX PF00787.19 EME26075.1 - 0.015 15.0 0.6 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 PX domain Pkinase PF00069.20 EME26076.1 - 1.3e-64 217.8 0.0 1.8e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26076.1 - 5.1e-31 107.6 0.0 1.2e-30 106.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26076.1 - 0.019 13.9 0.0 0.79 8.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EME26076.1 - 0.065 12.9 0.0 0.91 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PcfK PF14058.1 EME26077.1 - 0.028 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 PcfK-like protein Arch_ATPase PF01637.13 EME26078.1 - 0.035 13.8 0.4 0.17 11.5 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase Sugar_tr PF00083.19 EME26082.1 - 7.4e-29 100.6 16.6 8.3e-29 100.4 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Adeno_E3_CR1 PF02440.10 EME26083.1 - 0.0018 17.7 0.1 0.64 9.5 0.0 2.8 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 DUF2951 PF11166.3 EME26083.1 - 1.7 8.5 6.4 2.3 8.1 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) ABC_tran PF00005.22 EME26084.1 - 1.1e-29 103.4 0.0 3.3e-29 101.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_assoc_C PF09821.4 EME26084.1 - 4.3e-28 98.0 0.1 6.8e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain AAA_21 PF13304.1 EME26084.1 - 1.2e-06 28.7 0.0 0.0085 16.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EME26084.1 - 0.00084 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME26084.1 - 0.0022 17.4 0.0 0.006 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EME26084.1 - 0.003 16.9 0.1 0.14 11.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME26084.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EME26084.1 - 0.012 15.3 0.1 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EME26084.1 - 0.024 14.3 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EME26084.1 - 0.038 14.1 0.5 0.37 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EME26084.1 - 0.039 14.2 0.6 0.088 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME26084.1 - 0.043 14.6 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME26084.1 - 0.11 11.9 0.1 1.9 7.8 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EME26084.1 - 0.13 12.5 0.1 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME26085.1 - 9.7e-30 103.6 0.0 2.7e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_assoc_C PF09821.4 EME26085.1 - 3.5e-28 98.2 0.1 5.5e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal AAA-associated domain AAA_21 PF13304.1 EME26085.1 - 8.6e-07 29.1 0.0 0.0071 16.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EME26085.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME26085.1 - 0.002 17.5 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EME26085.1 - 0.0021 17.5 0.1 0.12 11.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME26085.1 - 0.0078 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EME26085.1 - 0.011 15.4 0.1 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EME26085.1 - 0.019 14.7 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EME26085.1 - 0.03 14.4 0.5 0.32 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EME26085.1 - 0.031 14.6 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME26085.1 - 0.036 14.8 0.0 0.077 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME26085.1 - 0.078 12.4 0.1 1.7 8.0 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EME26085.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain tRNA-synt_1 PF00133.17 EME26086.1 - 2e-137 458.7 1.6 2.4e-136 455.1 1.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EME26086.1 - 1.6e-12 46.7 0.9 2.4e-07 29.7 0.1 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EME26086.1 - 6e-06 25.6 0.0 0.0002 20.6 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 DUF4028 PF13220.1 EME26086.1 - 0.049 13.2 0.2 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) tRNA-synt_1d PF00750.14 EME26086.1 - 0.086 11.6 0.0 0.25 10.0 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (R) Aa_trans PF01490.13 EME26088.1 - 7.6e-41 139.9 31.1 4.1e-33 114.4 11.9 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EME26088.1 - 1.7e-12 46.5 23.0 1.7e-12 46.5 16.0 2.6 2 1 0 2 2 2 2 Amino acid permease Trp_Tyr_perm PF03222.8 EME26088.1 - 4.4e-06 25.7 14.0 4.4e-06 25.7 9.7 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family TMEMspv1-c74-12 PF11044.3 EME26088.1 - 0.047 13.2 1.9 0.38 10.3 1.3 2.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fmp27 PF10344.4 EME26090.1 - 0.035 11.8 0.0 0.035 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Peptidase_M28 PF04389.12 EME26091.1 - 3.4e-31 108.3 0.0 5.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EME26091.1 - 0.00072 19.1 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Anoctamin PF04547.7 EME26092.1 - 2.8e-49 168.0 18.2 3.4e-49 167.7 12.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.7 EME26093.1 - 9.2e-38 130.0 1.9 1.1e-37 129.7 1.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel CTP_transf_2 PF01467.21 EME26094.1 - 1e-07 32.1 0.0 2.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase GCV_T PF01571.16 EME26095.1 - 5.3e-64 215.4 0.0 6.6e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME26095.1 - 5e-24 84.1 0.1 9.7e-24 83.2 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EME26095.1 - 0.00023 21.0 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 EME26095.1 - 0.04 13.8 0.0 11 6.0 0.0 2.6 1 1 0 2 2 2 0 GTP-binding protein TrmE N-terminus Citrate_synt PF00285.16 EME26096.1 - 2.7e-66 223.7 0.0 3.1e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase TPR_2 PF07719.12 EME26097.1 - 4.7e-11 41.7 20.2 0.0056 16.5 2.3 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME26097.1 - 3.1e-10 39.5 17.2 0.00095 18.7 2.5 5.5 5 1 0 5 5 5 3 TPR repeat Apc3 PF12895.2 EME26097.1 - 2.8e-09 36.9 30.4 0.00017 21.6 5.7 6.7 2 1 5 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EME26097.1 - 4.9e-09 36.0 9.6 6.4 7.7 0.2 9.1 8 1 2 10 10 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME26097.1 - 1e-05 25.7 20.7 0.16 12.3 1.8 6.6 3 1 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME26097.1 - 0.00013 21.8 23.9 0.25 11.3 2.2 6.9 6 3 1 8 8 8 3 Tetratricopeptide repeat SRP72 PF08492.7 EME26097.1 - 0.00028 21.1 15.0 0.00028 21.1 10.4 2.6 1 1 1 2 2 1 1 SRP72 RNA-binding domain TPR_4 PF07721.9 EME26097.1 - 0.00078 19.6 1.8 23 5.7 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME26097.1 - 0.001 19.6 7.6 0.23 12.1 0.3 5.4 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF3366 PF11846.3 EME26097.1 - 0.0026 17.6 0.9 0.82 9.5 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3366) TPR_6 PF13174.1 EME26097.1 - 0.01 16.2 14.7 0.98 10.0 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat WHG PF13305.1 EME26097.1 - 0.039 14.5 0.5 0.35 11.4 0.0 2.7 3 0 0 3 3 3 0 WHG domain TPR_8 PF13181.1 EME26097.1 - 0.12 12.2 11.6 33 4.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME26097.1 - 0.89 9.5 9.7 3.1 7.8 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME26097.1 - 2.2 8.6 10.5 12 6.3 0.3 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME26097.1 - 8 6.2 28.7 0.15 11.6 2.8 7.8 11 0 0 11 11 11 0 Tetratricopeptide repeat Radical_SAM PF04055.16 EME26098.1 - 9.2e-16 58.4 0.1 2.3e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EME26098.1 - 5.3e-11 42.3 0.0 1.4e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME26098.1 - 0.0024 17.9 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 EME26099.1 - 1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Toxin_18 PF08087.6 EME26099.1 - 0.073 12.8 0.8 0.15 11.8 0.6 1.5 1 0 0 1 1 1 0 Conotoxin O-superfamily Ribosomal_S21e PF01249.13 EME26100.1 - 1.2e-34 118.1 0.2 1.3e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAIM1 PF06905.8 EME26100.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) NTP_transferase PF00483.18 EME26102.1 - 2.2e-17 63.2 0.0 3.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EME26102.1 - 1.6e-06 27.3 7.4 0.0018 17.7 2.4 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EME26102.1 - 3.7e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME26102.1 - 0.022 14.2 4.0 0.12 11.9 2.4 2.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pet191_N PF10203.4 EME26102.1 - 0.098 12.7 6.7 2.2 8.3 1.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NTP_transferase PF00483.18 EME26103.1 - 4.9e-14 52.2 0.0 7.3e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EME26103.1 - 1.4e-06 27.4 7.3 0.0017 17.7 2.3 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EME26103.1 - 0.0004 20.4 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME26103.1 - 0.023 14.2 4.1 0.12 11.9 2.5 2.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pet191_N PF10203.4 EME26103.1 - 0.096 12.7 6.7 2.2 8.3 1.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Tim17 PF02466.14 EME26104.1 - 1e-29 103.1 7.5 1.3e-29 102.7 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SNARE PF05739.14 EME26110.1 - 1.4e-14 53.4 3.1 1.4e-14 53.4 2.1 2.7 3 0 0 3 3 3 1 SNARE domain Serine_rich PF08824.5 EME26110.1 - 0.00015 21.5 1.6 0.00015 21.5 1.1 2.2 2 0 0 2 2 2 1 Serine rich protein interaction domain HxlR PF01638.12 EME26110.1 - 0.11 12.0 4.2 0.16 11.5 0.1 2.6 2 1 0 2 2 2 0 HxlR-like helix-turn-helix V-SNARE PF05008.10 EME26110.1 - 0.79 9.9 14.0 0.13 12.4 1.6 3.9 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.16 EME26110.1 - 1.2 9.4 12.0 1 9.6 2.0 3.7 2 2 1 3 3 3 0 Spectrin repeat IncA PF04156.9 EME26110.1 - 1.5 8.3 36.4 0.069 12.7 7.4 2.6 1 1 2 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 EME26110.1 - 1.6 9.1 17.8 4.9 7.6 0.5 4.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 EME26110.1 - 4.2 6.8 15.7 0.46 9.9 6.0 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LXG PF04740.7 EME26110.1 - 9.7 5.9 14.7 1.1 9.0 1.4 3.8 1 1 2 4 4 4 0 LXG domain of WXG superfamily SNARE PF05739.14 EME26111.1 - 1.4e-14 53.4 3.1 1.4e-14 53.4 2.1 2.7 3 0 0 3 3 3 1 SNARE domain Serine_rich PF08824.5 EME26111.1 - 0.00015 21.5 1.6 0.00015 21.5 1.1 2.2 2 0 0 2 2 2 1 Serine rich protein interaction domain HxlR PF01638.12 EME26111.1 - 0.11 12.0 4.2 0.16 11.5 0.1 2.6 2 1 0 2 2 2 0 HxlR-like helix-turn-helix V-SNARE PF05008.10 EME26111.1 - 0.79 9.9 14.0 0.13 12.4 1.6 3.9 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.16 EME26111.1 - 1.2 9.4 12.0 1 9.6 2.0 3.7 2 2 1 3 3 3 0 Spectrin repeat IncA PF04156.9 EME26111.1 - 1.5 8.3 36.4 0.069 12.7 7.4 2.6 1 1 2 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 EME26111.1 - 1.6 9.1 17.8 4.9 7.6 0.5 4.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 EME26111.1 - 4.2 6.8 15.7 0.46 9.9 6.0 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LXG PF04740.7 EME26111.1 - 9.7 5.9 14.7 1.1 9.0 1.4 3.8 1 1 2 4 4 4 0 LXG domain of WXG superfamily Ecl1 PF12855.2 EME26112.1 - 0.096 11.9 3.2 0.14 11.5 2.0 1.5 1 1 0 1 1 1 0 Life-span regulatory factor MIP PF00230.15 EME26113.1 - 2.3e-48 164.6 7.4 2.8e-48 164.3 5.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PAD_porph PF04371.10 EME26114.1 - 1.8e-82 277.0 0.0 2e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DUF913 PF06025.7 EME26115.1 - 1.4e-30 106.3 0.2 1.6e-22 79.8 0.0 4.0 3 1 1 4 4 4 2 Domain of Unknown Function (DUF913) UBA PF00627.26 EME26115.1 - 0.00014 21.5 0.1 0.00049 19.8 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.5 EME26115.1 - 0.059 12.9 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Grp1_Fun34_YaaH PF01184.14 EME26116.1 - 5e-25 88.0 20.2 6.8e-25 87.6 14.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family S-AdoMet_synt_N PF00438.15 EME26120.1 - 2.3e-42 143.2 0.2 3e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DHO_dh PF01180.16 EME26123.1 - 6.7e-42 143.4 0.1 7.8e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EME26123.1 - 0.0025 17.1 2.0 0.022 14.0 0.2 2.0 1 1 1 2 2 2 2 PcrB family DUF4363 PF14276.1 EME26125.1 - 0.044 13.4 1.1 0.074 12.7 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) CorA PF01544.13 EME26125.1 - 0.29 10.1 4.1 0.79 8.6 1.8 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Ribonuc_red_sm PF00268.16 EME26126.1 - 1.4e-57 194.8 8.5 2e-57 194.3 5.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF2626 PF11117.3 EME26126.1 - 0.0011 19.2 0.3 0.003 17.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2626) DUF2027 PF09640.5 EME26126.1 - 0.017 14.4 0.3 0.035 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) GRIM-19 PF06212.7 EME26126.1 - 0.13 11.9 0.5 0.4 10.3 0.1 2.0 3 0 0 3 3 3 0 GRIM-19 protein Histone PF00125.19 EME26127.1 - 2.1e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME26127.1 - 1.6e-05 24.8 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME26127.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated GCS PF03074.11 EME26128.1 - 0.041 12.9 0.0 0.041 12.9 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase Glycos_transf_1 PF00534.15 EME26129.1 - 6.5e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME26129.1 - 5.7e-14 52.4 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EME26129.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.1 EME26129.1 - 0.0049 17.0 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF1510 PF07423.6 EME26130.1 - 0.0049 16.2 0.7 0.0074 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EME26130.1 - 0.35 10.3 11.3 0.71 9.3 7.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Arch_ATPase PF01637.13 EME26134.1 - 0.0021 17.8 0.1 0.013 15.1 0.0 2.2 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME26134.1 - 0.025 14.7 0.0 0.44 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Bud13 PF09736.4 EME26135.1 - 0.013 15.7 0.5 0.72 10.1 0.0 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Pro-kuma_activ PF09286.6 EME26136.1 - 3.2e-16 59.6 0.0 5.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME26136.1 - 0.0057 15.8 0.3 0.01 15.0 0.2 1.3 1 0 0 1 1 1 1 Subtilase family RNA_pol_Rpb1_5 PF04998.12 EME26138.1 - 4e-86 288.6 0.0 8.8e-86 287.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 EME26138.1 - 7.5e-54 182.3 0.1 1.2e-53 181.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EME26138.1 - 4.7e-38 130.3 0.0 7.2e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EME26138.1 - 4.9e-32 110.4 5.6 8e-32 109.7 3.9 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EME26138.1 - 2.5e-31 107.5 0.9 4.8e-31 106.6 0.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EME26138.1 - 1.5e-12 46.5 191.6 0.0079 16.2 5.5 14.0 9 2 0 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat Ish1 PF10281.4 EME26139.1 - 0.13 12.3 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein zf-DHHC PF01529.15 EME26141.1 - 5.4 6.3 9.2 5.9 6.2 6.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-C3HC4_3 PF13920.1 EME26142.1 - 0.0086 15.7 9.4 0.019 14.6 6.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Exo5 PF09810.4 EME26142.1 - 0.036 13.3 3.9 0.049 12.8 2.7 1.1 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease zf-RING_2 PF13639.1 EME26142.1 - 0.1 12.4 9.7 0.17 11.7 6.7 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2360 PF10152.4 EME26142.1 - 0.55 10.4 8.3 1 9.6 5.8 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EME26142.1 - 0.69 9.2 18.4 1 8.7 12.8 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EME26142.1 - 1.4 8.5 6.8 2.4 7.7 4.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C3HC4_2 PF13923.1 EME26142.1 - 2.5 8.1 10.3 4.5 7.3 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME26142.1 - 3.9 7.2 11.0 15 5.4 7.8 1.8 1 1 1 2 2 2 0 zinc-RING finger domain Jacalin PF01419.12 EME26143.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Jacalin-like lectin domain PLRV_ORF5 PF01690.12 EME26143.1 - 0.43 9.6 9.3 0.64 9.0 6.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Lamp PF01299.12 EME26143.1 - 0.85 8.6 5.5 1.6 7.8 3.8 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DNA_pol_B PF00136.16 EME26144.1 - 1.9e-41 142.3 0.0 3.5e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME26144.1 - 2.4e-27 95.6 1.6 4.2e-27 94.8 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.8 EME26144.1 - 5.2e-05 22.0 4.7 0.00017 20.4 0.1 2.5 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 EME26144.1 - 0.0013 18.2 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_3 PF08408.5 EME26144.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_pol_A_exo1 PF01612.15 EME26144.1 - 0.081 12.4 0.2 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease DUF3696 PF12476.3 EME26145.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3696) DegS PF05384.6 EME26146.1 - 0.051 12.7 1.6 0.072 12.3 1.1 1.3 1 0 0 1 1 1 0 Sensor protein DegS TMEM191C PF15194.1 EME26147.1 - 0.066 13.1 0.8 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 TMEM191C family LRR_6 PF13516.1 EME26151.1 - 2.9e-44 144.1 40.9 0.001 18.8 0.4 12.5 12 0 0 12 12 12 11 Leucine Rich repeat LRR_1 PF00560.28 EME26151.1 - 7e-15 52.7 7.4 10 6.5 0.0 11.7 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_7 PF13504.1 EME26151.1 - 3.8e-10 38.2 13.6 30 5.4 0.0 11.5 11 0 0 11 11 11 0 Leucine rich repeat LRR_4 PF12799.2 EME26151.1 - 1e-08 34.5 40.3 0.089 12.4 2.6 6.7 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) zf-TRAF PF02176.13 EME26151.1 - 6.5e-07 29.6 17.1 1.5e-06 28.5 2.2 3.7 2 1 1 3 3 2 2 TRAF-type zinc finger DUF2202 PF09968.4 EME26151.1 - 1.1e-06 28.3 19.0 2.9 7.5 0.1 8.6 1 1 9 10 10 10 2 Uncharacterized protein domain (DUF2202) Gallidermin PF02052.10 EME26151.1 - 1.2e-06 28.5 19.4 7.5 6.7 0.0 10.4 11 0 0 11 11 11 1 Gallidermin DM PF00751.13 EME26151.1 - 0.00072 19.0 1.3 0.00072 19.0 0.9 3.9 2 2 1 3 3 2 1 DM DNA binding domain zf-RING_6 PF14835.1 EME26151.1 - 0.0015 18.2 15.5 0.0068 16.1 10.7 2.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SpoU_sub_bind PF08032.7 EME26151.1 - 0.0016 18.5 8.4 30 4.8 0.0 6.1 1 1 7 9 9 9 0 RNA 2'-O ribose methyltransferase substrate binding zf-RING_5 PF14634.1 EME26151.1 - 0.0072 16.0 23.1 0.0072 16.0 16.0 2.8 2 1 0 2 2 1 1 zinc-RING finger domain LRR_8 PF13855.1 EME26151.1 - 0.0098 15.6 33.3 4.5 7.0 2.6 7.2 1 1 7 8 8 8 3 Leucine rich repeat zf-RING_2 PF13639.1 EME26151.1 - 0.015 15.1 21.6 0.015 15.1 15.0 2.9 2 1 0 2 2 1 0 Ring finger domain YycC PF14174.1 EME26151.1 - 0.018 14.7 3.8 2.4e+02 1.4 0.0 7.0 10 0 0 10 10 8 0 YycC-like protein YscW PF09619.5 EME26151.1 - 0.19 11.4 1.3 1.4e+02 2.1 0.0 5.0 1 1 6 7 7 7 0 Type III secretion system lipoprotein chaperone (YscW) YusW PF14039.1 EME26151.1 - 0.39 11.0 15.7 11 6.3 0.6 5.1 1 1 3 4 4 4 0 YusW-like protein YjcQ PF09639.5 EME26151.1 - 0.85 9.7 15.6 60 3.8 0.4 7.4 1 1 7 8 8 8 0 YjcQ protein DUF1103 PF06513.6 EME26151.1 - 2.6 7.4 6.9 11 5.3 0.0 3.4 1 1 2 3 3 3 0 Repeat of unknown function (DUF1103) Aminotran_5 PF00266.14 EME26152.1 - 1.7e-19 69.8 0.0 3.5e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V MOSC_N PF03476.11 EME26152.1 - 5.8e-10 38.9 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME26152.1 - 1.4e-08 34.2 0.0 4.9e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 MOSC domain Aminotran_5 PF00266.14 EME26153.1 - 6.2e-18 64.6 0.0 1.5e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V MOSC_N PF03476.11 EME26153.1 - 5.9e-10 38.8 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME26153.1 - 1.4e-08 34.2 0.0 4.9e-08 32.5 0.0 1.8 1 1 1 2 2 2 1 MOSC domain Aldedh PF00171.17 EME26154.1 - 2.1e-164 547.2 0.1 2.4e-164 547.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME26154.1 - 1.1e-05 24.7 0.0 0.0088 15.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 EME26154.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) HEAT_2 PF13646.1 EME26156.1 - 1e-14 54.5 0.8 8.6e-09 35.5 0.3 3.1 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EME26156.1 - 9.6e-05 22.7 3.2 0.012 16.0 0.0 3.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT_PBS PF03130.11 EME26156.1 - 0.00018 21.6 1.2 1.1 9.8 0.1 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT PF02985.17 EME26156.1 - 0.00033 20.4 3.2 0.76 10.0 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 EME26156.1 - 0.0012 17.3 0.0 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EME26156.1 - 0.019 14.7 0.3 0.039 13.8 0.1 1.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF479 PF04336.7 EME26156.1 - 0.077 13.1 0.1 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF479 DUF155 PF02582.9 EME26157.1 - 5.9e-48 163.0 0.0 1e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Rifin_STEVOR PF02009.11 EME26157.1 - 0.12 12.0 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EME26157.1 - 0.39 10.4 1.5 2.2 7.9 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family DUF2909 PF11137.3 EME26157.1 - 0.56 9.9 3.2 1.1 9.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) mit_SMPDase PF14724.1 EME26158.1 - 1.3e-05 23.2 0.2 0.0013 16.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase mit_SMPDase PF14724.1 EME26159.1 - 1.3e-05 23.2 0.2 0.0013 16.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase SQS_PSY PF00494.14 EME26164.1 - 6.4e-37 127.2 1.1 7.4e-37 127.0 0.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase FA_desaturase PF00487.19 EME26166.1 - 1.5e-28 99.9 5.9 1.5e-28 99.9 4.1 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3487 PF11990.3 EME26166.1 - 0.4 10.0 2.0 1 8.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Arch_ATPase PF01637.13 EME26167.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase GDC-P PF02347.11 EME26168.1 - 2.7e-127 425.0 0.1 7.6e-112 374.1 0.0 3.3 3 1 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EME26168.1 - 1.3e-06 27.4 0.1 0.0011 17.8 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME26168.1 - 0.065 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Mito_carr PF00153.22 EME26169.1 - 9.7e-68 223.9 1.9 7.8e-22 76.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EME26170.1 - 3e-69 228.8 1.7 7.1e-22 76.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SLT_2 PF13406.1 EME26170.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain SAM_1 PF00536.25 EME26171.1 - 3.3e-06 27.1 0.0 5.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EME26171.1 - 6.1e-06 25.9 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Fasciclin PF02469.17 EME26172.1 - 4.3e-22 78.4 0.1 5.6e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain RNA_pol_Rpb1_2 PF00623.15 EME26174.1 - 5.5e-29 101.2 0.0 9e-19 68.0 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EME26174.1 - 2.9e-19 69.5 17.2 1.3e-18 67.4 2.3 3.6 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EME26174.1 - 7.7e-15 54.8 0.0 5.7e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 EME26174.1 - 6.1e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyco_trans_1_4 PF13692.1 EME26175.1 - 1.2e-09 38.4 0.0 4.6e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EME26175.1 - 9.8e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME26175.1 - 7.5e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DPRP PF04244.8 EME26175.1 - 0.059 12.8 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein NIF PF03031.13 EME26176.1 - 3.8e-14 52.6 0.0 6.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3589 PF12141.3 EME26176.1 - 3.3e-09 35.5 0.0 4.7e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) CENP-B_dimeris PF09026.5 EME26177.1 - 7.8e-05 22.8 7.1 0.00011 22.3 4.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EME26177.1 - 0.042 13.4 7.7 0.049 13.2 5.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3246 PF11596.3 EME26177.1 - 0.063 12.5 0.3 0.069 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Myc_N PF01056.13 EME26177.1 - 0.18 10.9 2.0 0.2 10.7 1.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Mpp10 PF04006.7 EME26177.1 - 0.29 9.4 7.1 0.33 9.2 4.9 1.1 1 0 0 1 1 1 0 Mpp10 protein eIF-3c_N PF05470.7 EME26177.1 - 0.51 8.3 2.6 0.55 8.2 1.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.1 EME26177.1 - 0.75 9.4 3.3 0.97 9.1 2.3 1.2 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.6 EME26177.1 - 0.8 9.5 8.9 1.1 9.1 6.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 EME26177.1 - 0.95 7.2 9.9 1.1 7.1 6.9 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EME26177.1 - 0.98 9.7 12.5 1.4 9.2 8.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bd3614_N PF14442.1 EME26177.1 - 1.1 9.1 5.5 1.7 8.6 3.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF688 PF05097.7 EME26177.1 - 1.5 7.6 3.6 1.7 7.5 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) CDC45 PF02724.9 EME26177.1 - 2.1 6.2 6.0 2.6 5.9 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EME26177.1 - 2.3 7.7 18.5 3.3 7.2 12.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Tom22 PF04281.8 EME26177.1 - 3.9 6.9 7.2 5.6 6.4 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NOA36 PF06524.7 EME26177.1 - 4.4 6.4 11.7 6 6.0 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 EME26177.1 - 5.7 6.1 8.0 6.6 5.9 5.6 1.1 1 0 0 1 1 1 0 SDA1 ANAPC15 PF15243.1 EME26177.1 - 6.2 6.9 15.2 9.5 6.3 10.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 EME26177.1 - 6.3 5.4 22.2 8.3 5.0 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Evr1_Alr PF04777.8 EME26178.1 - 8.7e-14 51.2 0.0 2.8e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Erv1 / Alr family RNA_pol_Rpb1_5 PF04998.12 EME26178.1 - 4e-10 39.4 1.6 0.00047 19.5 0.0 3.0 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 5 Pox_E10 PF04805.7 EME26178.1 - 0.0028 17.1 0.0 0.0083 15.6 0.0 1.8 1 0 0 1 1 1 1 E10-like protein conserved region UQ_con PF00179.21 EME26179.1 - 4.3e-23 81.2 0.1 4.9e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BTK PF00779.14 EME26179.1 - 0.17 11.4 0.6 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 BTK motif BRI3BP PF14965.1 EME26186.1 - 0.1 11.9 2.1 0.11 11.8 1.5 1.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 ELF PF03317.8 EME26186.1 - 0.39 9.9 8.0 0.45 9.7 5.6 1.0 1 0 0 1 1 1 0 ELF protein DUF674 PF05056.7 EME26187.1 - 0.046 12.3 0.1 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) PPR PF01535.15 EME26192.1 - 0.01 15.7 0.1 0.062 13.3 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 EME26192.1 - 0.081 12.9 0.3 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 PPR repeat family Sugar_tr PF00083.19 EME26194.1 - 8.1e-20 70.8 3.0 1e-15 57.3 0.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter 2OG-FeII_Oxy PF03171.15 EME26195.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily EamA PF00892.15 EME26196.1 - 9.2e-11 41.8 43.5 3.9e-08 33.3 3.6 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EME26196.1 - 1.6e-05 25.0 33.8 4.4e-05 23.6 0.8 3.7 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EME26196.1 - 0.00016 21.3 1.6 0.00016 21.3 1.1 3.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family DUF914 PF06027.7 EME26196.1 - 0.00034 19.5 13.9 0.00034 19.5 9.6 2.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 EME26196.1 - 0.32 10.0 12.5 0.046 12.8 1.8 2.5 2 0 0 2 2 2 0 Nucleotide-sugar transporter WD40 PF00400.27 EME26197.1 - 1.9e-08 33.8 0.6 0.082 12.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CAP_assoc_N PF14504.1 EME26197.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 CAP-associated N-terminal Sec1 PF00995.18 EME26198.1 - 3.7e-105 352.7 0.0 4.5e-105 352.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family FUSC_2 PF13515.1 EME26199.1 - 0.002 18.0 39.5 0.064 13.1 12.0 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2421 PF10334.4 EME26199.1 - 0.013 15.1 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) zf-CCCH PF00642.19 EME26200.1 - 4.2e-15 55.0 14.1 5e-09 35.6 1.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME26200.1 - 0.051 13.6 13.6 0.4 10.7 2.8 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EME26200.1 - 0.15 11.6 1.1 11 5.6 0.1 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Histone PF00125.19 EME26201.1 - 1.6e-30 105.0 0.3 2.2e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME26201.1 - 0.014 15.5 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EME26201.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.22 EME26202.1 - 2.9e-09 37.3 0.0 5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME26202.1 - 7.8e-05 22.7 0.2 0.00014 21.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME26202.1 - 9.4e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME26202.1 - 0.0013 19.1 0.2 0.0031 17.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EME26202.1 - 0.0036 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 EME26202.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EME26202.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EME26202.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 MutS domain V Cullin_binding PF03556.10 EME26203.1 - 3.7e-37 127.0 2.0 5.2e-37 126.5 1.4 1.2 1 0 0 1 1 1 1 Cullin binding GP41 PF00517.12 EME26203.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.3 1 1 0 1 1 1 0 Retroviral envelope protein DUF493 PF04359.9 EME26204.1 - 5e-20 71.6 0.0 8.2e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF493) LRR_4 PF12799.2 EME26205.1 - 1.7e-27 94.5 44.1 2.2e-08 33.5 4.3 6.6 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME26205.1 - 3.9e-15 55.3 35.6 4.3e-06 26.3 5.4 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EME26205.1 - 3.4e-09 35.4 39.0 0.4 10.8 0.4 8.9 7 2 0 7 7 7 5 Leucine Rich Repeat LRR_9 PF14580.1 EME26205.1 - 4e-09 36.2 14.4 6e-05 22.6 2.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 EME26205.1 - 2.8e-07 29.6 33.6 1.3 9.5 0.2 9.2 9 0 0 9 9 9 4 Leucine rich repeat LRR_6 PF13516.1 EME26205.1 - 0.00022 20.9 35.3 0.19 11.9 0.2 8.8 8 2 1 9 9 9 3 Leucine Rich repeat ANTH PF07651.11 EME26206.1 - 1.1e-30 106.3 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EME26206.1 - 1.8e-07 31.0 0.0 8.5e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 ENTH domain DUF1993 PF09351.5 EME26206.1 - 0.064 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) ANTH PF07651.11 EME26207.1 - 1.1e-30 106.3 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EME26207.1 - 1.8e-07 31.0 0.0 8.4e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 ENTH domain DUF1993 PF09351.5 EME26207.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) RRM_1 PF00076.17 EME26208.1 - 2.8e-07 30.0 0.1 5.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME26208.1 - 5.3e-05 23.0 1.0 0.0074 16.1 0.1 2.3 2 0 0 2 2 2 2 RNA binding motif RRM_6 PF14259.1 EME26208.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26208.1 - 0.001 18.8 0.2 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.2 EME26209.1 - 1.6e-32 112.6 0.4 2.3e-32 112.1 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME26209.1 - 8.6e-18 64.5 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_S17 PF00366.15 EME26213.1 - 3e-29 100.8 0.7 5.2e-29 100.1 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S17 Ribosomal_L18ae PF01775.12 EME26215.1 - 8.1e-52 174.3 1.4 1.1e-51 173.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Sugar_tr PF00083.19 EME26217.1 - 5.3e-05 21.9 0.0 6.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26217.1 - 5.7e-05 21.9 1.0 7.4e-05 21.6 0.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_hydroxylase PF04116.8 EME26218.1 - 5e-10 39.7 11.4 5e-10 39.7 7.9 2.8 1 1 2 3 3 3 2 Fatty acid hydroxylase superfamily Alpha_adaptin_C PF02296.11 EME26221.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 2 1 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain PPR PF01535.15 EME26222.1 - 0.0035 17.2 0.1 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 EME26222.1 - 0.066 13.2 0.8 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 PPR repeat family AAA_22 PF13401.1 EME26229.1 - 0.035 14.2 0.0 0.18 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain Trehalase_Ca-bi PF07492.6 EME26230.1 - 0.13 11.6 2.0 11 5.4 0.0 2.9 3 0 0 3 3 3 0 Neutral trehalase Ca2+ binding domain SpoIIIAH PF12685.2 EME26233.1 - 1.5 8.3 9.7 2.5 7.5 6.8 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF1980 PF09323.5 EME26233.1 - 3 7.5 7.7 0.37 10.5 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) UCH PF00443.24 EME26235.1 - 6.8e-27 94.2 0.0 9.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME26235.1 - 6.3e-13 48.8 0.0 1.6e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EME26235.1 - 2.6e-11 43.0 0.5 3.8e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 UBA/TS-N domain GTP_cyclohydroI PF01227.17 EME26236.1 - 1.6e-69 232.7 0.6 2.5e-69 232.1 0.4 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EME26236.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein HAUS5 PF14817.1 EME26236.1 - 0.048 12.2 0.1 0.091 11.2 0.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 TGT PF01702.13 EME26237.1 - 3e-61 206.7 0.0 4.4e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase NAD_binding_10 PF13460.1 EME26238.1 - 3.7e-08 33.5 0.0 4.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HemS PF05171.7 EME26238.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain ETF_QO PF05187.8 EME26239.1 - 5.3e-41 139.0 0.0 8.9e-41 138.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EME26239.1 - 4.4e-07 29.1 0.2 0.027 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EME26239.1 - 9e-07 28.2 0.0 2.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EME26239.1 - 2.7e-06 27.2 0.0 1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME26239.1 - 2.7e-05 23.1 0.2 0.0011 17.8 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EME26239.1 - 0.00076 19.4 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME26239.1 - 0.00084 17.9 0.0 0.0014 17.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EME26239.1 - 0.00088 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EME26239.1 - 0.0013 19.0 1.0 0.0032 17.8 0.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 EME26239.1 - 0.0021 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME26239.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME26239.1 - 0.019 14.0 0.0 0.055 12.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 EME26239.1 - 0.12 12.7 0.1 26 5.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME26239.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCM PF00493.18 EME26240.1 - 1e-99 333.5 0.0 1.5e-99 332.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EME26240.1 - 3.9e-09 35.9 0.3 8.1e-07 28.4 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME26240.1 - 4e-08 33.0 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 EME26240.1 - 5.4e-08 33.3 0.0 3.2e-07 30.8 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.6 EME26240.1 - 3.1e-05 23.5 0.0 6.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME26240.1 - 0.0005 19.5 0.0 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EME26240.1 - 0.0077 16.4 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME26240.1 - 0.047 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NAD_binding_1 PF00175.16 EME26241.1 - 7.5e-10 39.3 0.0 1.9e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME26241.1 - 0.00017 21.6 0.0 0.00064 19.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DUF1517 PF07466.6 EME26241.1 - 0.00033 19.7 7.5 0.00033 19.7 5.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) NAD_binding_6 PF08030.7 EME26241.1 - 0.0013 18.6 0.0 0.0043 16.9 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain RRM_1 PF00076.17 EME26242.1 - 2.7e-55 183.8 0.0 5.2e-18 64.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26242.1 - 3.8e-42 142.1 0.0 5.2e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26242.1 - 3e-18 65.4 0.0 0.00024 20.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME26242.1 - 3e-05 23.6 0.0 0.29 10.8 0.0 3.3 3 1 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.1 EME26242.1 - 0.1 12.3 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arch_ATPase PF01637.13 EME26243.1 - 0.015 14.9 0.1 0.091 12.4 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase Sugar_tr PF00083.19 EME26246.1 - 6.8e-86 288.6 26.2 9.2e-86 288.1 18.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26246.1 - 5.3e-22 78.0 59.0 2.4e-21 75.8 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EME26246.1 - 3.3 5.7 11.0 0.63 8.0 4.2 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Arch_ATPase PF01637.13 EME26247.1 - 0.00028 20.6 0.0 0.0021 17.7 0.0 2.2 1 1 1 2 2 2 2 Archaeal ATPase ATE_C PF04377.10 EME26248.1 - 0.012 15.6 0.1 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus Arch_ATPase PF01637.13 EME26250.1 - 0.0006 19.5 0.1 0.0042 16.8 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME26250.1 - 0.19 11.8 0.3 3.3 7.8 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EME26251.1 - 0.03 14.2 0.4 0.098 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain Transp_cyt_pur PF02133.10 EME26252.1 - 1.7e-19 69.7 27.0 1.7e-19 69.7 18.7 2.8 2 1 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.14 EME26254.1 - 1.5e-52 177.3 0.0 2.3e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME26254.1 - 3e-18 65.5 0.0 3.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF3039 PF11238.3 EME26254.1 - 0.0013 18.1 0.4 0.64 9.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3039) NAD_binding_7 PF13241.1 EME26254.1 - 0.014 15.6 0.1 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 EME26254.1 - 0.017 14.5 0.1 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EME26254.1 - 0.065 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DOT1 PF08123.8 EME26254.1 - 0.11 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 HlyIII PF03006.15 EME26255.1 - 1.3e-28 99.9 14.4 1.4e-26 93.2 10.0 2.1 1 1 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.1 EME26255.1 - 1.2e-08 34.1 1.1 0.055 13.5 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 EME26255.1 - 1e-05 25.0 1.4 0.025 14.2 0.1 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME26255.1 - 0.002 17.8 2.3 0.18 11.6 0.3 3.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EME26255.1 - 0.0021 17.9 5.0 3.5 8.2 0.1 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EME26255.1 - 0.003 17.3 3.9 7.1 7.0 0.4 4.5 3 1 0 3 3 3 1 Leucine Rich Repeat HlyIII PF03006.15 EME26256.1 - 2.1e-35 122.1 8.6 2.9e-35 121.6 5.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.1 EME26256.1 - 1.5e-08 33.8 0.4 0.052 13.6 0.0 4.1 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 EME26256.1 - 9.6e-06 25.1 1.5 0.023 14.3 0.1 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME26256.1 - 0.0016 18.1 2.2 0.16 11.7 0.3 3.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EME26256.1 - 0.0019 18.0 5.0 3.3 8.3 0.1 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EME26256.1 - 0.0031 17.3 4.1 6.8 7.1 0.5 4.5 3 1 0 3 3 3 1 Leucine Rich Repeat WD40 PF00400.27 EME26257.1 - 1.1e-27 94.7 3.6 2.2e-07 30.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat WD40 PF00400.27 EME26258.1 - 9.7e-28 95.0 3.4 2.3e-07 30.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Biotin_lipoyl PF00364.17 EME26259.1 - 1.8e-25 88.3 6.8 7.8e-18 63.8 1.8 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EME26259.1 - 1.2e-06 28.0 0.3 0.002 17.7 0.0 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like PYNP_C PF07831.8 EME26259.1 - 0.0013 18.1 1.0 0.75 9.2 0.1 2.5 2 1 0 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain QRPTase_N PF02749.11 EME26259.1 - 0.003 17.3 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 EME26259.1 - 0.0098 15.0 1.8 1.8 7.6 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EME26259.1 - 0.02 15.1 0.4 9.4 6.6 0.0 2.6 3 0 0 3 3 3 0 HlyD family secretion protein Acyl-CoA_ox_N PF14749.1 EME26259.1 - 0.09 13.0 0.1 6.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Glyco_hydro_35 PF01301.14 EME26260.1 - 8.6e-91 304.5 3.2 1.2e-90 304.0 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 EME26260.1 - 2.8e-08 33.2 2.9 2.9e-07 29.9 0.4 2.9 1 1 1 2 2 2 1 Beta-galactosidase Sugar_tr PF00083.19 EME26261.1 - 2.7e-64 217.4 23.5 5.8e-46 156.9 3.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME26261.1 - 9.2e-14 50.9 40.5 7.1e-09 34.8 9.4 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily AAA_22 PF13401.1 EME26262.1 - 0.0011 19.1 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain SAM_1 PF00536.25 EME26263.1 - 0.0009 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME26264.1 - 0.00046 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EME26264.1 - 0.15 11.9 0.1 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) XPG_N PF00752.12 EME26266.1 - 0.00033 20.8 0.0 0.00046 20.4 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain Mito_carr PF00153.22 EME26267.1 - 2.9e-66 219.2 0.5 3e-22 78.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Rep_fac-A_C PF08646.5 EME26268.1 - 7.1e-42 142.5 0.0 9.5e-37 125.9 0.0 3.2 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EME26268.1 - 2.2e-28 98.0 1.4 5.7e-28 96.6 1.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EME26268.1 - 2.9e-16 59.0 0.4 7e-13 48.2 0.1 3.6 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain Med20 PF08612.6 EME26269.1 - 2.3e-09 36.7 2.0 7.7e-09 35.0 1.4 1.8 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Mito_carr PF00153.22 EME26270.1 - 1.6e-66 220.0 0.6 1.5e-22 79.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GCD14 PF08704.5 EME26274.1 - 4.2e-46 157.4 0.0 5.2e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EME26274.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26274.1 - 0.00017 22.1 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME26274.1 - 0.00035 20.1 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SPX PF03105.14 EME26275.1 - 1.3e-35 123.5 13.7 3.1e-20 73.1 3.5 2.1 1 1 1 2 2 2 2 SPX domain YkuI_C PF10388.4 EME26275.1 - 0.57 9.8 5.1 5.1 6.7 0.0 2.9 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain Maf PF02545.9 EME26276.1 - 1.6e-34 118.7 0.1 4.2e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Maf-like protein Xpo1 PF08389.7 EME26276.1 - 0.072 13.0 16.4 0.16 11.8 0.1 5.0 3 2 1 4 4 4 0 Exportin 1-like protein VKOR PF07884.9 EME26277.1 - 1.4e-25 89.7 14.0 1.4e-25 89.7 9.7 1.5 1 1 0 1 1 1 1 Vitamin K epoxide reductase family GRAM PF02893.15 EME26277.1 - 0.014 14.8 1.4 0.23 11.0 0.2 2.6 2 0 0 2 2 2 0 GRAM domain Thioredoxin PF00085.15 EME26277.1 - 0.037 13.7 0.1 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Ig_Tie2_1 PF10430.4 EME26277.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 FBPase PF00316.15 EME26278.1 - 2.2e-73 246.9 0.0 2.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EME26278.1 - 0.055 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family NNMT_PNMT_TEMT PF01234.12 EME26278.1 - 0.085 11.8 0.1 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CAAD PF14159.1 EME26279.1 - 4e-05 23.1 2.7 6.4e-05 22.5 1.7 1.6 1 1 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SPOUT_MTase PF02590.12 EME26279.1 - 0.072 12.8 0.3 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Glyco_transf_11 PF01531.11 EME26280.1 - 8.5e-10 38.0 0.3 2.4e-08 33.3 0.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 11 CTK3_C PF12350.3 EME26280.1 - 0.087 12.8 0.3 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus adh_short PF00106.20 EME26281.1 - 1.2e-42 145.7 1.1 1.6e-42 145.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME26281.1 - 9.3e-26 91.0 0.8 1.1e-25 90.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME26281.1 - 4.6e-19 68.7 0.6 6.5e-19 68.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME26281.1 - 0.0059 16.0 0.4 0.01 15.2 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME26281.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EME26281.1 - 0.037 13.1 0.7 0.12 11.4 0.1 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ABC2_membrane PF01061.19 EME26282.1 - 3.8e-87 290.8 50.5 2.9e-46 157.3 13.2 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EME26282.1 - 5.9e-18 65.4 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EME26282.1 - 2.8e-10 39.7 11.3 2.8e-10 39.7 7.8 4.3 3 2 1 4 4 4 1 ABC-2 family transporter protein AAA_21 PF13304.1 EME26282.1 - 4.9e-06 26.7 0.0 0.014 15.3 0.0 3.0 3 1 0 3 3 3 2 AAA domain PDR_CDR PF06422.7 EME26282.1 - 4e-05 23.2 5.3 0.068 12.8 1.2 2.9 2 0 0 2 2 2 2 CDR ABC transporter PDR_assoc PF08370.6 EME26282.1 - 0.00022 20.6 1.2 0.00022 20.6 0.8 4.0 4 0 0 4 4 3 2 Plant PDR ABC transporter associated AAA_25 PF13481.1 EME26282.1 - 0.00052 19.4 0.3 0.0011 18.3 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME26282.1 - 0.0022 18.0 0.1 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME26282.1 - 0.0027 17.2 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EME26282.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME26282.1 - 0.0037 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME26282.1 - 0.0052 17.5 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME26282.1 - 0.0062 16.4 0.9 0.0095 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EME26282.1 - 0.0089 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME26282.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.9 EME26282.1 - 0.031 13.2 0.1 0.65 8.9 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase NACHT PF05729.7 EME26282.1 - 0.056 13.0 0.4 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EME26282.1 - 0.057 12.9 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EME26282.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EME26282.1 - 0.13 12.0 0.3 0.52 10.0 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF87 UPF0079 PF02367.12 EME26282.1 - 0.17 11.5 0.1 0.36 10.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EME26282.1 - 0.2 11.0 3.0 0.079 12.3 0.2 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EME26282.1 - 1 9.6 2.7 0.78 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Pox_Ag35 PF03286.9 EME26283.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1903 PF08991.5 EME26283.1 - 0.25 11.5 2.9 0.55 10.4 0.4 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF1903) ATP_transf PF09830.4 EME26284.1 - 0.063 13.0 0.1 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP adenylyltransferase Proteasome PF00227.21 EME26285.1 - 2.2e-44 151.0 0.1 2.8e-44 150.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF1253 PF06862.7 EME26286.1 - 1.7e-120 402.4 11.4 2.6e-120 401.8 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF3349 PF11829.3 EME26287.1 - 0.034 14.5 0.1 0.037 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) DUF2222 PF09984.4 EME26287.1 - 0.038 13.4 0.1 0.042 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Ovate PF04844.8 EME26287.1 - 0.12 12.1 1.8 0.25 11.1 0.2 2.0 1 1 1 2 2 2 0 Transcriptional repressor, ovate LRR_6 PF13516.1 EME26288.1 - 3.4e-41 134.6 53.6 0.00012 21.8 0.2 13.6 13 1 1 14 14 13 10 Leucine Rich repeat LRR_1 PF00560.28 EME26288.1 - 3.9e-12 44.4 14.8 16 5.9 0.0 12.3 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_4 PF12799.2 EME26288.1 - 2.3e-10 39.8 46.6 0.014 15.0 0.9 6.9 2 1 2 6 6 6 5 Leucine Rich repeats (2 copies) YycC PF14174.1 EME26288.1 - 3.5e-07 29.7 0.2 36 4.1 0.0 8.1 9 0 0 9 9 9 0 YycC-like protein zf-TRAF PF02176.13 EME26288.1 - 1.7e-06 28.2 3.3 1.7e-06 28.2 2.3 3.9 2 1 1 3 3 2 2 TRAF-type zinc finger LRR_7 PF13504.1 EME26288.1 - 1.1e-05 24.8 21.3 54 4.6 0.0 11.7 11 1 1 12 12 12 0 Leucine rich repeat DUF2202 PF09968.4 EME26288.1 - 1.8e-05 24.4 16.1 12 5.4 0.0 7.8 1 1 7 8 8 8 1 Uncharacterized protein domain (DUF2202) Gallidermin PF02052.10 EME26288.1 - 0.00022 21.2 15.5 19 5.4 0.0 9.6 10 0 0 10 10 10 0 Gallidermin DM PF00751.13 EME26288.1 - 0.0012 18.2 1.4 0.0012 18.2 1.0 3.8 2 1 1 3 3 2 1 DM DNA binding domain zf-RING_6 PF14835.1 EME26288.1 - 0.0019 17.9 15.2 0.0071 16.1 10.5 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SpoU_sub_bind PF08032.7 EME26288.1 - 0.03 14.4 9.0 35 4.6 0.0 5.9 4 2 4 8 8 8 0 RNA 2'-O ribose methyltransferase substrate binding YusW PF14039.1 EME26288.1 - 0.16 12.2 12.8 11 6.4 0.2 5.0 2 1 2 4 4 4 0 YusW-like protein UCH PF00443.24 EME26289.1 - 5.4e-41 140.4 0.1 6.7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EME26289.1 - 7.6e-12 45.1 1.0 1.9e-11 43.9 0.7 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EME26289.1 - 8.7e-05 22.0 0.1 0.00027 20.4 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FAA_hydrolase PF01557.13 EME26290.1 - 8.3e-59 198.6 0.0 1e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PEMT PF04191.8 EME26291.1 - 1.5e-43 147.1 10.3 2.7e-24 85.2 1.1 3.7 4 0 0 4 4 4 2 Phospholipid methyltransferase GFO_IDH_MocA PF01408.17 EME26292.1 - 2.4e-26 92.5 0.1 4.2e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME26292.1 - 4e-11 42.7 0.0 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.14 EME26292.1 - 0.0073 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME26292.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_3 PF03447.11 EME26292.1 - 0.048 14.0 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Amidohydro_1 PF01979.15 EME26293.1 - 1.9e-35 123.0 0.0 4e-35 122.0 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family PNP_UDP_1 PF01048.15 EME26293.1 - 1.6e-29 102.5 0.0 2.4e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Amidohydro_4 PF13147.1 EME26293.1 - 5.7e-13 49.5 0.0 4e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EME26293.1 - 7.8e-13 48.3 0.0 8.7e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME26293.1 - 1.7e-06 27.7 0.0 6.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 EME26293.1 - 0.0051 15.7 0.0 0.021 13.7 0.0 1.8 2 0 0 2 2 2 1 Adenosine/AMP deaminase Skp1_POZ PF03931.10 EME26294.1 - 2.8e-12 46.5 0.0 3.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TPMT PF05724.6 EME26294.1 - 0.052 12.9 0.1 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RNB PF00773.14 EME26295.1 - 4.8e-21 75.3 5.2 1.5e-20 73.8 0.1 3.1 3 0 0 3 3 3 1 RNB domain TPR_11 PF13414.1 EME26295.1 - 2.4e-12 46.2 1.3 2.4e-12 46.2 0.9 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EME26295.1 - 7.2e-10 38.0 8.4 0.00021 20.7 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME26295.1 - 9.9e-05 22.2 0.4 9.9e-05 22.2 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME26295.1 - 0.00012 21.7 12.9 0.017 14.9 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME26295.1 - 0.024 14.3 3.0 2.7 8.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SprA-related PF12118.3 EME26295.1 - 2.7 7.2 5.2 4.7 6.4 3.6 1.3 1 0 0 1 1 1 0 SprA-related family Transthyretin PF00576.16 EME26296.1 - 2.7e-32 110.9 0.0 3e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Disulph_isomer PF06491.6 EME26296.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Disulphide isomerase DUF2964 PF11177.3 EME26297.1 - 0.044 13.7 1.3 0.062 13.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Sigma_reg_N PF13800.1 EME26297.1 - 0.073 13.1 0.0 0.081 12.9 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Complex1_51K PF01512.12 EME26298.1 - 6.8e-49 165.4 0.0 1.2e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EME26298.1 - 1.6e-19 68.7 0.5 3.1e-19 67.8 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EME26298.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Methyltransf_2 PF00891.13 EME26299.1 - 1.2e-16 60.6 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EME26299.1 - 1.2e-09 38.7 0.0 2.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26299.1 - 7.2e-09 36.0 0.1 2.8e-08 34.1 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.9 EME26299.1 - 7.6e-09 35.1 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EME26299.1 - 1.1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26299.1 - 1.5e-07 31.4 0.0 8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26299.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26299.1 - 2.5e-06 27.7 0.0 5.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME26299.1 - 2e-05 23.8 0.0 3.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME26299.1 - 2.4e-05 24.7 0.1 7.1e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EME26299.1 - 0.00093 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EME26299.1 - 0.003 16.5 0.0 0.0048 15.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 EME26299.1 - 0.0037 16.3 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 EME26299.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 EME26299.1 - 0.0097 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MarR PF01047.17 EME26299.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF938 PF06080.7 EME26299.1 - 0.04 13.4 0.0 0.19 11.2 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF938) Ded_cyto PF06920.8 EME26299.1 - 0.081 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Dedicator of cytokinesis CBFD_NFYB_HMF PF00808.18 EME26300.1 - 2.5e-08 33.8 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TMF_TATA_bd PF12325.3 EME26303.1 - 0.0068 16.1 2.3 0.0094 15.6 1.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 EME26303.1 - 0.031 14.0 0.9 0.039 13.7 0.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EME26303.1 - 0.033 14.0 2.6 0.092 12.5 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EME26303.1 - 0.05 13.1 1.8 0.063 12.8 1.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 EME26303.1 - 0.071 12.8 1.2 0.078 12.7 0.2 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper GreA_GreB_N PF03449.10 EME26303.1 - 0.14 12.1 6.3 0.27 11.3 1.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Spc42p PF11544.3 EME26303.1 - 0.2 11.6 0.3 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF4201 PF13870.1 EME26303.1 - 0.27 10.6 6.4 0.69 9.3 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1843 PF08898.5 EME26303.1 - 0.33 11.0 1.6 0.46 10.5 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) ADIP PF11559.3 EME26303.1 - 0.39 10.6 5.8 5.7 6.8 0.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 EME26303.1 - 0.54 10.7 4.9 0.38 11.2 0.8 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EME26303.1 - 1.1 8.8 4.9 1.7 8.2 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EME26303.1 - 8 6.3 7.6 1.4 8.7 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SRP54 PF00448.17 EME26304.1 - 1.5e-58 197.4 0.0 4.2e-58 196.0 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EME26304.1 - 1.2e-25 90.4 18.9 1.8e-25 89.8 13.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EME26304.1 - 1.3e-06 28.3 0.3 1.3e-06 28.3 0.2 2.5 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.1 EME26304.1 - 4e-06 26.5 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME26304.1 - 6.8e-05 23.0 0.0 0.00066 19.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EME26304.1 - 9.7e-05 21.2 3.2 0.00028 19.7 0.0 2.7 3 1 0 3 3 3 1 ArgK protein CbiA PF01656.18 EME26304.1 - 0.00025 20.4 0.9 0.00025 20.4 0.6 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EME26304.1 - 0.00091 18.9 0.1 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EME26304.1 - 0.0039 16.9 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 NTPase Fer4_NifH PF00142.13 EME26304.1 - 0.011 14.9 0.0 0.027 13.6 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA PF00004.24 EME26304.1 - 0.016 15.4 0.0 0.13 12.5 0.0 2.6 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME26304.1 - 0.037 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME26304.1 - 0.066 14.0 0.1 0.41 11.4 0.0 2.5 2 0 0 2 2 1 0 AAA domain ETF PF01012.16 EME26304.1 - 0.12 12.0 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein domain ABC_tran PF00005.22 EME26304.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.0 2 1 0 2 2 1 0 ABC transporter LRR_9 PF14580.1 EME26305.1 - 5.4e-57 192.1 0.6 6.9e-57 191.8 0.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EME26305.1 - 2.6e-08 33.4 7.3 2.8e-06 26.9 2.4 2.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EME26305.1 - 3e-08 33.0 10.2 8.3e-05 22.1 1.6 4.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EME26305.1 - 6.9e-05 22.5 2.1 7.7 6.9 0.4 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 EME26305.1 - 0.00012 21.5 8.7 8.2 6.8 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EME26305.1 - 0.01 15.9 5.6 18 6.1 0.0 4.6 4 0 0 4 4 4 1 Leucine rich repeat GA PF01468.12 EME26305.1 - 0.035 14.2 0.5 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 GA module Glycos_transf_1 PF00534.15 EME26306.1 - 8.6e-30 103.4 0.0 1.6e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1752 PF08550.5 EME26306.1 - 1.3e-11 43.8 0.5 2.7e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_trans_1_4 PF13692.1 EME26306.1 - 4.7e-11 42.9 0.0 1.6e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME26306.1 - 5.7e-11 42.5 0.1 3.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME26306.1 - 0.00083 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Phage_GP20 PF06810.6 EME26307.1 - 0.033 13.6 7.9 0.078 12.4 5.1 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 EME26307.1 - 0.037 13.8 14.1 0.063 13.1 5.4 2.7 3 0 0 3 3 3 0 Tropomyosin like Snapin_Pallidin PF14712.1 EME26307.1 - 0.21 11.8 8.3 7.3 6.9 5.2 2.6 1 1 1 2 2 2 0 Snapin/Pallidin NPV_P10 PF05531.7 EME26307.1 - 0.4 10.9 5.6 3 8.1 0.4 3.9 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.1 EME26307.1 - 0.99 9.3 12.1 0.23 11.3 2.5 3.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 COG2 PF06148.6 EME26307.1 - 1.2 9.0 7.3 8.4 6.2 3.1 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EME26307.1 - 1.6 8.4 7.2 2.6e+02 1.3 5.0 2.6 1 1 0 1 1 1 0 Laminin Domain II Rabaptin PF03528.10 EME26307.1 - 1.8 8.5 13.2 9.6 6.1 0.7 2.8 1 1 1 2 2 2 0 Rabaptin Cmc1 PF08583.5 EME26308.1 - 1.1e-15 57.1 6.1 1.7e-15 56.5 4.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EME26308.1 - 0.0056 16.5 4.6 0.73 9.8 0.2 2.5 2 0 0 2 2 2 2 CHCH domain Ndufs5 PF10200.4 EME26308.1 - 0.03 14.3 1.9 0.044 13.7 1.3 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.8 EME26308.1 - 0.23 11.5 3.0 0.48 10.4 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 EME26308.1 - 0.64 10.1 4.9 6.5 6.8 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 WLM PF08325.5 EME26309.1 - 1.1e-34 119.9 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EME26309.1 - 5.9e-05 22.9 2.3 6.7e-05 22.7 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.18 EME26309.1 - 0.0003 20.1 0.7 0.0003 20.1 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin family SprT-like PF10263.4 EME26309.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 SprT-like family ChuX_HutX PF06228.8 EME26309.1 - 0.0076 15.6 0.1 0.031 13.6 0.0 2.0 2 1 1 3 3 3 1 Haem utilisation ChuX/HutX DUF2407 PF10302.4 EME26309.1 - 0.054 13.6 0.3 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WLM PF08325.5 EME26310.1 - 1.1e-34 119.9 0.0 1.7e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EME26310.1 - 5.9e-05 22.9 2.3 6.7e-05 22.7 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.18 EME26310.1 - 0.0003 20.1 0.7 0.0003 20.1 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin family SprT-like PF10263.4 EME26310.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 SprT-like family ChuX_HutX PF06228.8 EME26310.1 - 0.0076 15.6 0.1 0.031 13.6 0.0 2.0 2 1 1 3 3 3 1 Haem utilisation ChuX/HutX DUF2407 PF10302.4 EME26310.1 - 0.054 13.6 0.3 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3546 PF12066.3 EME26311.1 - 7.6e-20 70.9 12.2 3.6e-19 68.7 8.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EME26311.1 - 3.9e-06 27.2 0.1 1.1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EME26311.1 - 0.047 13.2 0.3 0.047 13.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Ribosomal_60s PF00428.14 EME26311.1 - 0.053 13.9 1.9 0.15 12.4 1.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein ATP_bind_1 PF03029.12 EME26312.1 - 2.8e-77 259.4 0.2 4.1e-77 258.9 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EME26312.1 - 3e-07 30.0 3.5 9e-07 28.5 0.1 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EME26312.1 - 3.2e-06 26.1 0.2 0.053 12.2 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 EME26312.1 - 3.3e-06 27.2 0.1 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EME26312.1 - 1.2e-05 26.1 0.0 2.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EME26312.1 - 1.9e-05 23.9 0.2 0.0014 17.9 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.1 EME26312.1 - 2.3e-05 24.2 0.1 9.5e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 EME26312.1 - 4.6e-05 22.9 0.0 9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EME26312.1 - 5.7e-05 23.2 0.2 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME26312.1 - 5.8e-05 22.6 0.2 0.071 12.5 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EME26312.1 - 8.3e-05 22.3 0.2 0.00031 20.4 0.0 2.0 3 0 0 3 3 1 1 NACHT domain MMR_HSR1 PF01926.18 EME26312.1 - 9.6e-05 22.3 0.0 0.00029 20.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EME26312.1 - 0.00011 21.6 0.1 0.0062 16.0 0.0 3.3 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EME26312.1 - 0.00032 19.9 0.2 0.33 10.1 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EME26312.1 - 0.00033 20.2 0.0 0.00082 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain SRP54 PF00448.17 EME26312.1 - 0.00044 19.7 0.2 0.0047 16.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arf PF00025.16 EME26312.1 - 0.00048 19.4 0.7 0.06 12.5 0.0 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.1 EME26312.1 - 0.0007 19.8 0.0 0.0024 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EME26312.1 - 0.0012 19.3 3.8 0.015 15.8 0.2 3.2 2 2 0 2 2 2 1 Miro-like protein MobB PF03205.9 EME26312.1 - 0.0012 18.5 0.2 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EME26312.1 - 0.0017 18.2 1.9 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EME26312.1 - 0.0018 17.9 0.3 0.019 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Ras PF00071.17 EME26312.1 - 0.0026 17.1 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 Ras family T2SE PF00437.15 EME26312.1 - 0.0027 16.6 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EME26312.1 - 0.0038 16.7 0.2 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EME26312.1 - 0.0047 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME26312.1 - 0.005 16.2 0.2 0.017 14.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EME26312.1 - 0.011 15.9 0.7 0.092 12.9 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EME26312.1 - 0.015 14.9 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EME26312.1 - 0.017 14.8 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EME26312.1 - 0.018 14.1 0.1 0.36 9.9 0.1 2.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EME26312.1 - 0.022 14.3 0.1 0.05 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EME26312.1 - 0.024 14.5 0.1 0.22 11.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EME26312.1 - 0.025 13.5 1.0 0.21 10.5 0.0 2.6 2 1 0 2 2 2 0 Septin ArsA_ATPase PF02374.10 EME26312.1 - 0.037 13.0 1.2 0.099 11.6 0.0 2.3 2 2 0 2 2 2 0 Anion-transporting ATPase AAA_14 PF13173.1 EME26312.1 - 0.038 13.8 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EME26312.1 - 0.041 13.2 0.0 0.13 11.5 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase FtsK_SpoIIIE PF01580.13 EME26312.1 - 0.056 12.9 0.3 0.2 11.1 0.2 2.0 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EME26312.1 - 0.07 13.0 0.7 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EME26312.1 - 0.085 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EME26312.1 - 0.086 12.3 0.4 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME26312.1 - 0.22 11.8 3.7 28 4.9 2.2 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME26312.1 - 0.3 11.3 3.2 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter TGF_beta_GS PF08515.7 EME26312.1 - 0.31 10.4 0.1 0.31 10.4 0.0 2.0 2 0 0 2 2 1 0 Transforming growth factor beta type I GS-motif Dynamin_N PF00350.18 EME26312.1 - 3 7.6 6.6 0.69 9.7 0.0 3.0 2 2 0 2 2 2 0 Dynamin family zf-DHHC PF01529.15 EME26313.1 - 1.6e-43 148.1 4.3 1.6e-43 148.1 3.0 2.5 2 1 1 3 3 3 2 DHHC palmitoyltransferase EcsB PF05975.7 EME26313.1 - 2.1 6.7 10.1 1.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF2207 PF09972.4 EME26313.1 - 4.8 5.6 7.6 3.8 5.9 0.1 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2105 PF09878.4 EME26313.1 - 8.3 5.9 10.1 0.13 11.8 0.4 2.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2105) Rhodanese PF00581.15 EME26314.1 - 1.2e-25 90.0 0.0 2.1e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain UPF0113 PF03657.8 EME26315.1 - 5.9e-15 55.2 0.2 7e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EME26315.1 - 0.0003 20.4 0.0 0.00077 19.1 0.0 1.7 2 0 0 2 2 2 1 PUA domain PsbP PF01789.11 EME26315.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 PsbP HhH-GPD PF00730.20 EME26316.1 - 5.2e-15 55.6 0.0 7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GatB_Yqey PF02637.13 EME26316.1 - 0.059 13.0 0.3 3.5 7.3 0.3 2.2 1 1 1 2 2 2 0 GatB domain Pyr_redox_2 PF07992.9 EME26317.1 - 6.2e-32 111.1 0.0 1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME26317.1 - 1e-25 89.9 0.0 1.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EME26317.1 - 1.1e-11 45.0 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME26317.1 - 1.3e-07 31.8 0.0 0.00093 19.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME26317.1 - 0.00031 19.7 0.2 0.0015 17.4 0.0 2.1 2 1 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EME26317.1 - 0.002 17.1 0.0 0.0045 15.9 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EME26317.1 - 0.0037 15.7 0.0 0.01 14.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EME26317.1 - 0.02 13.7 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME26317.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FA_hydroxylase PF04116.8 EME26318.1 - 1.6e-19 70.4 14.8 1.6e-19 70.4 10.2 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Ca_chan_IQ PF08763.6 EME26318.1 - 0.045 12.9 0.0 0.094 11.9 0.0 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain ABC_membrane PF00664.18 EME26321.1 - 7.9e-66 222.2 28.1 7.5e-33 114.1 8.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME26321.1 - 1.3e-52 177.7 0.0 1.6e-30 106.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME26321.1 - 5.9e-12 45.2 4.1 9e-05 21.8 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME26321.1 - 4e-08 33.5 0.1 0.58 10.0 0.0 4.4 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EME26321.1 - 1.5e-07 31.5 0.1 0.00044 20.2 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.1 EME26321.1 - 4.6e-07 29.4 0.0 0.014 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EME26321.1 - 4.7e-05 23.3 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EME26321.1 - 6.6e-05 22.1 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EME26321.1 - 7.4e-05 23.2 0.1 0.32 11.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EME26321.1 - 0.00053 20.8 0.0 0.6 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EME26321.1 - 0.00065 19.2 0.2 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EME26321.1 - 0.00074 18.9 0.2 1.4 8.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EME26321.1 - 0.0023 17.4 0.1 0.22 10.9 0.0 3.2 3 1 0 3 3 3 1 AAA-like domain IstB_IS21 PF01695.12 EME26321.1 - 0.0024 17.3 0.0 2.8 7.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_23 PF13476.1 EME26321.1 - 0.0031 17.8 9.7 0.0099 16.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 EME26321.1 - 0.0043 17.2 0.1 3.3 7.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EME26321.1 - 0.0058 16.8 0.1 0.36 11.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EME26321.1 - 0.0066 15.0 0.3 0.062 11.8 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.1 EME26321.1 - 0.0087 16.3 0.0 2.5 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EME26321.1 - 0.0093 14.7 0.0 3.1 6.5 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 EME26321.1 - 0.01 14.9 0.0 1.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 EME26321.1 - 0.011 14.6 0.0 0.61 8.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EME26321.1 - 0.021 14.6 0.2 0.93 9.2 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 EME26321.1 - 0.024 14.2 0.1 26 4.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EME26321.1 - 0.073 12.7 0.0 0.53 9.9 0.0 2.4 3 0 0 3 3 3 0 Archaeal ATPase MobB PF03205.9 EME26321.1 - 0.082 12.6 0.2 9.4 5.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EME26321.1 - 0.091 12.9 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.4 EME26321.1 - 0.11 12.0 0.7 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EME26321.1 - 0.19 11.6 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain HAD_2 PF13419.1 EME26322.1 - 2.4e-19 70.2 0.0 5e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME26322.1 - 1.7e-08 34.0 0.0 3.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME26322.1 - 2.9e-08 34.4 0.1 2.3e-06 28.1 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EME26322.1 - 0.091 12.2 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) UQ_con PF00179.21 EME26323.1 - 2.7e-53 179.1 0.0 3.1e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME26323.1 - 2.1e-05 24.2 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME26323.1 - 0.0017 18.2 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EME26323.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Clr5 PF14420.1 EME26323.1 - 0.08 12.8 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Clr5 domain Abhydrolase_6 PF12697.2 EME26324.1 - 5.8e-18 65.6 0.1 1.5e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AIG2_2 PF13772.1 EME26324.1 - 5.8e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family DAGAT PF03982.8 EME26324.1 - 2.4e-06 26.4 0.0 4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_1 PF00561.15 EME26324.1 - 8.3e-06 25.5 0.0 3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Acyltransferase PF01553.16 EME26324.1 - 1.6e-05 24.3 0.1 7.2e-05 22.2 0.1 2.1 3 1 0 3 3 3 1 Acyltransferase Abhydrolase_5 PF12695.2 EME26324.1 - 2.1e-05 24.2 0.0 7.9e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EME26324.1 - 0.017 14.7 0.0 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase PAP_fibrillin PF04755.7 EME26325.1 - 1.4e-22 80.3 0.0 2.3e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin ELO PF01151.13 EME26326.1 - 4.3e-30 104.8 16.6 5.4e-30 104.5 11.1 1.5 1 1 1 2 2 2 1 GNS1/SUR4 family tRNA-synt_2b PF00587.20 EME26327.1 - 3.6e-43 147.1 0.2 6.3e-43 146.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME26327.1 - 1.1e-12 47.6 0.0 5.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.9 EME26327.1 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RDD PF06271.7 EME26328.1 - 0.012 15.5 2.5 0.012 15.5 1.7 2.7 2 1 0 2 2 2 0 RDD family Baculo_PEP_C PF04513.7 EME26328.1 - 0.03 14.1 0.4 0.03 14.1 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4131 PF13567.1 EME26328.1 - 0.32 10.3 6.1 3.9 6.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EamA PF00892.15 EME26328.1 - 1.3 9.0 17.4 2.9 7.9 0.7 3.3 2 1 1 3 3 3 0 EamA-like transporter family Tweety PF04906.8 EME26328.1 - 1.8 6.8 9.2 0.024 13.0 1.3 1.7 2 0 0 2 2 2 0 Tweety Baculo_PEP_C PF04513.7 EME26329.1 - 0.035 13.9 0.4 0.035 13.9 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4131 PF13567.1 EME26329.1 - 0.66 9.3 6.5 5 6.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 EME26330.1 - 1e-87 294.6 33.4 1.2e-87 294.4 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26330.1 - 5.7e-26 91.0 28.5 5.7e-26 91.0 19.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_hydroxylase PF04116.8 EME26331.1 - 1.8e-12 47.6 12.0 1.8e-12 47.6 8.3 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CCSMST1 PF15013.1 EME26331.1 - 0.075 12.9 0.4 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 CCSMST1 family Pho88 PF10032.4 EME26332.1 - 1.8e-21 76.2 0.0 1.9e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Tcp11 PF05794.8 EME26333.1 - 5.2e-26 91.3 9.0 5.2e-26 91.3 6.3 1.6 2 0 0 2 2 2 1 T-complex protein 11 AAA_11 PF13086.1 EME26333.1 - 3.3 7.2 11.5 2.2 7.7 6.3 2.0 2 0 0 2 2 2 0 AAA domain UCR_hinge PF02320.11 EME26334.1 - 0.25 11.2 3.0 1.3 8.9 0.0 2.9 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein ThylakoidFormat PF11264.3 EME26335.1 - 3.7e-49 167.2 2.1 5.3e-49 166.7 1.5 1.3 1 0 0 1 1 1 1 Thylakoid formation protein DUF1848 PF08902.6 EME26335.1 - 0.0037 16.8 3.0 0.57 9.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1848) DUF106 PF01956.11 EME26336.1 - 2.5e-20 72.7 0.0 4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF106 PF01956.11 EME26337.1 - 3.2e-20 72.3 0.0 5.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cupin_8 PF13621.1 EME26338.1 - 3.4e-23 82.4 2.5 5.9e-22 78.3 1.7 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EME26338.1 - 1.3e-13 51.1 0.1 4.7e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EME26338.1 - 0.0008 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein UPF0167 PF03691.9 EME26338.1 - 0.0015 17.9 0.1 0.0047 16.3 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0167) GST_N_3 PF13417.1 EME26339.1 - 1e-10 41.6 0.9 2.2e-09 37.4 0.0 2.8 2 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME26339.1 - 2.7e-09 37.4 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EME26339.1 - 2.5e-08 33.7 0.6 6e-08 32.5 0.4 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 EME26339.1 - 4.9e-07 29.6 0.1 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME26339.1 - 4.4e-06 26.5 0.0 8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME26339.1 - 3.9e-05 23.5 0.1 0.00094 19.1 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 EME26339.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Sterol_MT_C PF08498.5 EME26340.1 - 1.1e-25 89.3 0.0 2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EME26340.1 - 2.7e-17 63.0 0.0 8.8e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EME26340.1 - 5.4e-15 55.1 0.0 8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EME26340.1 - 2e-12 46.9 0.0 2.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26340.1 - 3.3e-10 39.9 0.0 8.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26340.1 - 1.3e-08 35.1 0.0 8.4e-08 32.6 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME26340.1 - 2.1e-08 33.5 0.0 9.6e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME26340.1 - 3e-08 33.9 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26340.1 - 3.7e-08 33.9 0.0 7.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26340.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME26340.1 - 0.0014 18.0 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EME26340.1 - 0.057 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GLTP PF08718.6 EME26342.1 - 5.9e-33 114.0 0.0 8e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) KH_1 PF00013.24 EME26343.1 - 3.1e-07 29.9 0.0 6.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EME26343.1 - 2e-06 27.2 0.1 4.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 KH domain CorA PF01544.13 EME26343.1 - 0.15 11.0 0.3 0.24 10.4 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C3HC4_3 PF13920.1 EME26344.1 - 7.3e-09 35.1 16.0 2.1e-08 33.6 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME26344.1 - 0.00019 21.3 16.6 0.00019 21.3 11.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME26344.1 - 0.0027 17.3 17.5 0.0027 17.3 12.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NAPRTase PF04095.11 EME26344.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family QueC PF06508.8 EME26345.1 - 2.4e-73 245.8 0.0 2.7e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EME26345.1 - 2.7e-06 26.9 0.0 0.0006 19.3 0.0 2.1 2 0 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EME26345.1 - 1.3e-05 24.8 0.2 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EME26345.1 - 0.0047 15.8 0.0 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD synthase PAPS_reduct PF01507.14 EME26345.1 - 0.016 15.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EME26345.1 - 0.041 13.3 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 PP-loop family QueC PF06508.8 EME26346.1 - 2.4e-73 245.8 0.0 2.7e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EME26346.1 - 2.7e-06 26.9 0.0 0.0006 19.3 0.0 2.1 2 0 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EME26346.1 - 1.3e-05 24.8 0.2 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EME26346.1 - 0.0047 15.8 0.0 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD synthase PAPS_reduct PF01507.14 EME26346.1 - 0.016 15.0 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 EME26346.1 - 0.041 13.3 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 PP-loop family Pur_DNA_glyco PF02245.11 EME26347.1 - 6.3e-55 185.1 0.0 1e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Rep-A_N PF04057.7 EME26347.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EME26347.1 - 0.0095 15.7 0.0 0.035 13.9 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain K_trans PF02705.11 EME26348.1 - 1.5e-155 518.6 27.6 1.8e-155 518.3 19.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter 5_nucleotid PF05761.9 EME26349.1 - 4.1e-151 503.5 0.8 4.7e-151 503.3 0.5 1.0 1 0 0 1 1 1 1 5' nucleotidase family GCV_T PF01571.16 EME26350.1 - 3.1e-19 69.1 0.0 4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME26350.1 - 5.3e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FGE-sulfatase PF03781.11 EME26350.1 - 0.13 11.6 0.3 0.21 10.8 0.2 1.3 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 Prenyltrans PF00432.16 EME26352.1 - 1.5e-39 133.2 12.3 6.8e-13 47.9 0.3 6.9 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EME26352.1 - 6.8e-30 103.2 1.8 2.8e-10 40.1 0.1 5.2 2 2 5 7 7 7 6 Prenyltransferase-like Prenyltrans_2 PF13249.1 EME26352.1 - 1.7e-29 102.5 2.5 2e-11 44.2 0.0 6.0 3 2 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 EME26352.1 - 4.9e-09 35.7 0.6 4.2e-05 22.8 0.0 4.3 4 2 1 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 EME26352.1 - 5.4e-05 22.5 3.3 0.0002 20.6 0.0 3.4 4 0 0 4 4 4 1 A-macroglobulin complement component Mago-bind PF09282.5 EME26352.1 - 0.018 14.5 0.3 0.058 12.9 0.1 2.0 2 0 0 2 2 2 0 Mago binding Melibiase PF02065.13 EME26353.1 - 2e-24 86.0 0.5 1.6e-16 60.0 0.0 2.3 1 1 1 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EME26353.1 - 0.0022 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 NPCBM_assoc PF10633.4 EME26353.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Pkinase PF00069.20 EME26355.1 - 3.6e-49 167.2 0.0 6.6e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26355.1 - 3.5e-33 114.7 0.0 5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26355.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-CHY PF05495.7 EME26355.1 - 0.0054 16.8 1.8 0.019 15.0 1.3 2.0 1 0 0 1 1 1 1 CHY zinc finger IncA PF04156.9 EME26355.1 - 0.44 10.1 3.6 0.68 9.4 0.1 2.6 2 0 0 2 2 2 0 IncA protein Elongin_A PF06881.6 EME26356.1 - 0.12 12.7 3.5 0.099 13.0 0.9 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2505 PF10698.4 EME26357.1 - 0.0034 16.8 0.8 0.011 15.2 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) AAA_22 PF13401.1 EME26359.1 - 0.11 12.6 0.0 0.57 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF726 PF05277.7 EME26366.1 - 6.5e-75 252.1 0.1 2.1e-71 240.6 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF726) HSP70 PF00012.15 EME26366.1 - 1.5e-06 26.4 0.0 1.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Hsp70 protein IQ PF00612.22 EME26366.1 - 2.3e-05 23.6 1.4 7.1e-05 22.1 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Abhydrolase_6 PF12697.2 EME26366.1 - 0.0036 17.2 0.1 0.0096 15.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME26366.1 - 0.011 15.4 0.1 0.052 13.3 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Oleosin PF01277.12 EME26366.1 - 1.8 8.1 11.5 0.12 11.9 3.2 2.5 2 0 0 2 2 2 0 Oleosin Glyco_transf_22 PF03901.12 EME26367.1 - 8.1e-40 137.0 39.4 1.1e-39 136.6 27.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Acetyltransf_1 PF00583.19 EME26368.1 - 7.5e-12 45.1 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME26368.1 - 5.9e-08 32.7 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME26368.1 - 0.00017 21.4 0.0 0.0016 18.2 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME26368.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyltransferase PF01553.16 EME26369.1 - 8e-17 60.9 0.1 2.6e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 Acyltransferase DUF2789 PF10982.3 EME26369.1 - 0.092 12.7 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) OppC_N PF12911.2 EME26369.1 - 1.5 8.2 6.0 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HSP20 PF00011.16 EME26370.1 - 1.4e-26 92.2 1.2 1.7e-26 92.0 0.9 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EME26370.1 - 0.053 14.0 0.1 0.2 12.2 0.0 1.9 1 1 0 1 1 1 0 CS domain PCI PF01399.22 EME26373.1 - 6.9e-10 39.1 0.8 6.9e-10 39.1 0.6 2.5 2 1 0 2 2 2 1 PCI domain DUF772 PF05598.6 EME26373.1 - 0.038 13.8 0.1 0.52 10.2 0.1 2.5 2 1 0 2 2 2 0 Transposase domain (DUF772) Miro PF08477.8 EME26374.1 - 6.1e-39 133.1 0.0 7.1e-23 81.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EME26374.1 - 1.9e-29 102.1 0.0 2.5e-19 69.2 0.0 3.2 3 0 0 3 3 3 3 Ras family EF_assoc_2 PF08356.7 EME26374.1 - 1.6e-26 91.8 0.0 4.6e-26 90.4 0.0 1.8 2 0 0 2 2 1 1 EF hand associated MMR_HSR1 PF01926.18 EME26374.1 - 2.9e-13 49.8 0.0 7.1e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF_assoc_1 PF08355.7 EME26374.1 - 7e-11 41.2 0.1 2.8e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF-hand_1 PF00036.27 EME26374.1 - 6.7e-10 37.5 4.1 0.00036 19.6 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EME26374.1 - 1.4e-07 30.7 5.4 0.0044 16.7 0.2 3.2 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.1 EME26374.1 - 2.5e-07 30.7 3.3 0.0031 17.6 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair Dynamin_N PF00350.18 EME26374.1 - 1.4e-06 28.2 0.5 0.097 12.4 0.1 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EME26374.1 - 1.5e-06 27.8 0.0 0.0064 15.9 0.0 3.3 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EME26374.1 - 4e-06 26.1 0.0 5.9e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EME26374.1 - 2.3e-05 24.5 0.0 0.029 14.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain EF-hand_5 PF13202.1 EME26374.1 - 8.3e-05 21.7 13.3 0.0015 17.7 0.4 3.2 4 0 0 4 4 3 2 EF hand AAA_16 PF13191.1 EME26374.1 - 0.0001 22.3 0.0 0.72 9.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain ABC_tran PF00005.22 EME26374.1 - 0.00011 22.5 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EME26374.1 - 0.00046 19.4 0.0 0.77 8.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_24 PF13479.1 EME26374.1 - 0.00055 19.5 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EME26374.1 - 0.00065 19.4 0.0 0.018 14.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EME26374.1 - 0.00083 18.9 0.0 0.072 12.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EME26374.1 - 0.00087 19.4 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase EF-hand_10 PF14788.1 EME26374.1 - 0.0012 18.5 4.9 0.0096 15.5 0.2 2.7 2 0 0 2 2 2 1 EF hand FeoB_N PF02421.13 EME26374.1 - 0.0016 17.7 0.0 0.83 8.9 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 EME26374.1 - 0.0017 18.6 0.0 5.1 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EME26374.1 - 0.0017 17.8 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EME26374.1 - 0.0019 17.9 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Septin PF00735.13 EME26374.1 - 0.0024 16.9 0.0 0.55 9.1 0.0 2.8 3 0 0 3 3 3 1 Septin Gtr1_RagA PF04670.7 EME26374.1 - 0.0026 16.9 0.2 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region EF-hand_8 PF13833.1 EME26374.1 - 0.004 16.7 3.3 0.94 9.1 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain pair AAA_10 PF12846.2 EME26374.1 - 0.0045 16.4 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 EME26374.1 - 0.0063 15.6 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Adeno_IVa2 PF02456.10 EME26374.1 - 0.0065 15.1 0.2 1.4 7.5 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA PF00004.24 EME26374.1 - 0.0091 16.2 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IIGP PF05049.8 EME26374.1 - 0.012 14.4 0.0 0.66 8.7 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 EME26374.1 - 0.015 14.2 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EME26374.1 - 0.016 14.3 0.0 1.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.14 EME26374.1 - 0.016 14.6 0.1 7.8 5.9 0.0 3.2 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 EME26374.1 - 0.017 13.9 0.1 5.2 5.7 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family AAA_17 PF13207.1 EME26374.1 - 0.02 15.7 0.7 10 6.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.1 EME26374.1 - 0.022 14.7 0.0 7.8 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EME26374.1 - 0.023 13.3 0.0 0.46 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME26374.1 - 0.029 14.0 0.0 2.3 7.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_25 PF13481.1 EME26374.1 - 0.034 13.5 0.0 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME26374.1 - 0.036 13.9 0.0 6 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EME26374.1 - 0.036 13.9 0.1 1 9.2 0.0 2.8 2 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EME26374.1 - 0.089 12.2 0.0 21 4.5 0.0 3.5 5 0 0 5 5 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EME26374.1 - 0.15 11.5 0.1 22 4.5 0.0 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 EME26374.1 - 0.16 10.8 0.0 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 YqzE PF14038.1 EME26375.1 - 1.6 8.5 4.1 0.49 10.1 0.2 2.2 2 0 0 2 2 2 0 YqzE-like protein Gly_transf_sug PF04488.10 EME26376.1 - 1.2e-11 44.8 0.0 2.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EME26376.1 - 2.1e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EME26376.1 - 0.0088 14.5 0.0 0.024 13.1 0.0 1.6 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Ribonucleas_3_3 PF14622.1 EME26377.1 - 1.7e-23 82.9 0.0 4.6e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EME26377.1 - 1.3e-19 70.7 0.3 1.5e-17 64.0 0.0 2.6 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 EME26377.1 - 7.8e-17 61.6 1.9 1.6e-16 60.5 1.3 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif ATP_bind_4 PF01902.12 EME26378.1 - 6.9e-43 146.5 0.0 1.3e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EME26378.1 - 9.2e-27 93.2 0.0 3.1e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP COG2 PF06148.6 EME26379.1 - 0.0013 18.6 0.5 0.0013 18.6 0.4 3.3 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 UPF0016 PF01169.14 EME26380.1 - 5.3e-41 138.6 16.9 8.8e-22 77.0 2.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EME26380.1 - 1.1e-07 31.4 2.0 9e-05 21.9 0.2 2.2 2 0 0 2 2 2 2 Integral membrane protein TerC family Cad PF03596.8 EME26380.1 - 0.038 13.6 0.7 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Cadmium resistance transporter WW PF00397.21 EME26381.1 - 8.1e-31 105.5 40.6 4.4e-09 36.0 1.8 5.7 5 0 0 5 5 5 4 WW domain FF PF01846.14 EME26381.1 - 1.1e-13 50.9 21.9 4.1e-07 29.8 0.0 6.9 6 1 0 6 6 6 3 FF domain PQQ PF01011.16 EME26381.1 - 0.09 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Trp_Tyr_perm PF03222.8 EME26382.1 - 2.6e-59 201.0 42.5 3.3e-59 200.6 29.5 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 EME26382.1 - 0.00076 18.1 55.0 0.0011 17.5 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3007 PF11460.3 EME26382.1 - 0.049 13.7 0.4 0.049 13.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) FGGY_N PF00370.16 EME26383.1 - 2.7e-76 256.1 0.1 3.9e-76 255.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EME26383.1 - 1.5e-60 204.2 0.2 8.8e-60 201.7 0.1 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF364 PF04016.7 EME26384.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Med15_fungi PF05397.7 EME26384.1 - 0.43 10.5 2.3 1.5 8.8 1.6 1.8 1 1 0 1 1 1 0 Mediator complex subunit 15 Spermine_synth PF01564.12 EME26385.1 - 3.1e-92 307.9 0.0 4.6e-92 307.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EME26385.1 - 0.00062 19.3 0.0 0.00094 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26385.1 - 0.035 14.5 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME26385.1 - 0.094 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.15 EME26386.1 - 2.3e-20 73.0 0.0 2.7e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain PFK PF00365.15 EME26387.1 - 3.9e-37 127.7 0.7 6.1e-37 127.1 0.5 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 EME26387.1 - 0.0026 16.5 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EME26387.1 - 0.081 12.3 0.1 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF746 PF05344.6 EME26387.1 - 0.11 12.0 0.0 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DNA_topoisoIV PF00521.15 EME26388.1 - 0.021 13.6 0.8 0.034 12.9 0.5 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Acyl-CoA_dh_1 PF00441.19 EME26389.1 - 9.7e-44 149.0 2.4 1.3e-43 148.6 1.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME26389.1 - 6.7e-26 91.0 0.1 3.7e-25 88.7 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME26389.1 - 3.2e-20 72.7 0.1 6.1e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME26389.1 - 5.1e-15 54.7 0.0 1.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ImpE PF07024.8 EME26389.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 ImpE protein GTP_EFTU PF00009.22 EME26391.1 - 1.5e-53 181.0 0.0 2.4e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EME26391.1 - 6.1e-48 161.2 0.8 1.1e-47 160.4 0.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EME26391.1 - 1.9e-20 72.4 0.1 6.2e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME26391.1 - 2.7e-09 36.9 0.5 5.2e-09 36.0 0.4 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EME26391.1 - 7.4e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EME26391.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EME26391.1 - 1.4e-05 24.8 0.0 6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II PduV-EutP PF10662.4 EME26391.1 - 0.00017 21.0 0.1 0.0005 19.5 0.1 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EME26391.1 - 0.01 15.0 0.0 0.048 12.8 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EME26391.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein RRM_1 PF00076.17 EME26392.1 - 0.00048 19.7 0.0 0.0036 16.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calici_PP_N PF08405.6 EME26392.1 - 0.083 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal ABC1 PF03109.11 EME26393.1 - 9.4e-34 115.9 0.0 2.7e-33 114.4 0.0 1.8 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EME26393.1 - 6.9e-06 25.5 0.1 0.00058 19.2 0.0 2.9 1 1 2 3 3 3 1 RIO1 family APH PF01636.18 EME26393.1 - 6.3e-05 22.8 0.0 0.27 10.9 0.0 3.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family WaaY PF06176.6 EME26393.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 EME26393.1 - 0.03 13.4 0.0 0.36 9.9 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain DUF1495 PF07381.6 EME26393.1 - 0.1 12.3 0.0 5.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) PhoH PF02562.11 EME26394.1 - 2.2e-50 170.7 0.0 3.4e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.1 EME26394.1 - 4.9e-28 97.8 0.0 2.3e-27 95.7 0.0 2.1 1 1 0 1 1 1 1 PIN domain AAA_30 PF13604.1 EME26394.1 - 1.1e-07 31.6 0.0 0.0067 16.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME26394.1 - 6.2e-07 29.6 0.0 9e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EME26394.1 - 5.8e-05 23.2 0.0 0.014 15.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EME26394.1 - 0.00096 18.2 0.0 0.0051 15.8 0.0 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EME26394.1 - 0.0039 16.8 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EME26394.1 - 0.01 15.4 0.0 0.29 10.6 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EME26394.1 - 0.011 15.7 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 EME26394.1 - 0.018 14.1 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EME26394.1 - 0.023 14.1 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EME26394.1 - 0.064 12.5 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.12 EME26394.1 - 0.067 12.6 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MutS_V PF00488.16 EME26394.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 MutS domain V DEAD PF00270.24 EME26394.1 - 0.091 12.2 0.2 0.68 9.4 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase DUF3354 PF11834.3 EME26394.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) HHH PF00633.18 EME26395.1 - 3.6e-05 23.2 0.0 0.00017 21.1 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EME26395.1 - 0.00081 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EME26395.1 - 0.015 15.4 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2247 PF10004.4 EME26395.1 - 0.056 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) BRCT_assoc PF12820.2 EME26395.1 - 0.059 13.1 1.6 0.061 13.0 0.1 1.7 2 0 0 2 2 2 0 Serine-rich domain associated with BRCT Orthopox_A36R PF05950.6 EME26395.1 - 0.45 10.4 2.6 0.83 9.5 1.8 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein PP2C PF00481.16 EME26396.1 - 5.5e-30 104.5 0.0 1.7e-29 102.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME26396.1 - 3.4e-09 36.4 0.0 8.9e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME26396.1 - 7.4e-05 22.5 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) TAF8_C PF10406.4 EME26397.1 - 5.7e-05 23.0 1.6 0.00016 21.6 1.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EME26397.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated FSH1 PF03959.8 EME26398.1 - 7.2e-53 179.1 0.0 1.2e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Methyltransf_23 PF13489.1 EME26398.1 - 3.7e-12 46.2 0.0 1.4e-11 44.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26398.1 - 3.4e-11 43.4 0.0 7.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26398.1 - 4.2e-11 42.6 0.0 1.4e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26398.1 - 8.7e-08 32.5 0.0 2.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EME26398.1 - 8.9e-08 32.2 0.0 0.0015 18.4 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 EME26398.1 - 2.6e-07 31.2 0.0 7.1e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26398.1 - 9.8e-06 25.8 0.0 7e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EME26398.1 - 4e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME26398.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_9 PF08003.6 EME26398.1 - 0.0014 17.4 0.0 0.0046 15.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Abhydrolase_1 PF00561.15 EME26398.1 - 0.011 15.3 0.0 0.46 9.9 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ubie_methyltran PF01209.13 EME26398.1 - 0.013 14.5 0.0 0.083 11.9 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EME26398.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DLH PF01738.13 EME26398.1 - 0.043 13.1 0.1 0.19 10.9 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_32 PF13679.1 EME26398.1 - 0.083 12.5 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EME26398.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain SNF2_N PF00176.18 EME26399.1 - 7e-69 231.8 0.2 1.2e-68 231.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain RabGAP-TBC PF00566.13 EME26399.1 - 2e-46 158.1 0.2 6.8e-46 156.4 0.1 2.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Helicase_C PF00271.26 EME26399.1 - 1.6e-14 53.4 0.0 8.3e-14 51.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 EME26399.1 - 3.1e-13 49.1 3.7 5.7e-06 25.9 0.1 3.2 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EME26399.1 - 8.5e-08 32.3 0.3 4e-07 30.1 0.2 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DEAD PF00270.24 EME26399.1 - 8.6e-07 28.6 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EME26399.1 - 0.012 15.6 0.0 0.047 13.7 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain UCR_UQCRX_QCR9 PF05365.7 EME26400.1 - 7.6e-17 60.6 0.3 8.7e-17 60.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TGT PF01702.13 EME26401.1 - 8.1e-88 293.7 0.0 9.9e-88 293.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Histone PF00125.19 EME26402.1 - 2e-32 111.1 0.4 3.2e-32 110.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME26402.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EME26402.1 - 0.0051 16.1 0.4 0.015 14.5 0.3 1.8 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EME26402.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME26403.1 - 2e-14 53.4 0.5 2.4e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME26403.1 - 5.6e-05 23.2 0.1 9e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EME26403.1 - 0.00016 21.5 0.2 0.00022 21.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EME26403.1 - 0.00026 20.9 0.1 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME26403.1 - 0.0061 16.2 0.1 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EME26403.1 - 0.03 14.0 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EME26403.1 - 0.079 12.2 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EME26404.1 - 5.9e-24 83.9 0.1 8.6e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME26404.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EME26404.1 - 0.00036 20.7 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A eIF3g PF12353.3 EME26405.1 - 4e-24 84.9 1.2 6.2e-24 84.3 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EME26405.1 - 9.1e-21 73.2 0.0 1.6e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26405.1 - 6.5e-18 64.4 0.0 1.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26405.1 - 6.3e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 EME26405.1 - 0.0043 16.7 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_bind PF08675.6 EME26405.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 RNA binding domain Cofilin_ADF PF00241.15 EME26406.1 - 3.4e-31 107.7 1.6 4e-31 107.5 1.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ODC_AZ PF02100.12 EME26407.1 - 1.5e-17 63.0 0.1 2.9e-17 62.1 0.1 1.5 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme DUF3437 PF11919.3 EME26408.1 - 4.3e-26 90.4 0.1 1.7e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EME26408.1 - 0.049 13.7 10.4 0.091 12.8 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat SURF4 PF02077.10 EME26409.1 - 5.3e-48 163.7 3.3 6.4e-48 163.4 2.3 1.0 1 0 0 1 1 1 1 SURF4 family RINGv PF12906.2 EME26410.1 - 7.7e-16 57.8 7.6 7.7e-16 57.8 5.3 2.0 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EME26410.1 - 9.3 6.1 15.0 0.16 11.7 4.9 2.2 2 0 0 2 2 2 0 Ring finger domain RINGv PF12906.2 EME26411.1 - 7.4e-16 57.9 7.6 7.4e-16 57.9 5.3 2.0 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EME26411.1 - 6.9 6.5 14.7 0.16 11.8 4.9 2.2 2 0 0 2 2 2 0 Ring finger domain Ndc80_HEC PF03801.8 EME26412.1 - 1.1e-45 155.0 0.1 1.1e-45 155.0 0.1 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family Fzo_mitofusin PF04799.8 EME26412.1 - 0.00054 19.3 2.1 0.00054 19.3 1.5 4.5 1 1 5 6 6 6 2 fzo-like conserved region BLOC1_2 PF10046.4 EME26412.1 - 0.0036 17.3 7.5 0.0036 17.3 5.2 4.6 2 2 3 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.3 EME26412.1 - 0.44 7.8 49.6 0.52 7.5 11.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EME26412.1 - 0.62 8.6 54.8 0.16 10.5 10.8 3.9 1 1 3 4 4 4 0 Spc7 kinetochore protein ApoO PF09769.4 EME26412.1 - 1.2 8.8 14.9 5.6 6.6 2.4 3.9 2 2 1 3 3 3 0 Apolipoprotein O DRP PF06044.7 EME26413.1 - 0.069 12.1 0.1 0.071 12.0 0.1 1.0 1 0 0 1 1 1 0 Dam-replacing family Pkinase PF00069.20 EME26414.1 - 5e-59 199.5 0.2 6e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26414.1 - 1.5e-20 73.3 0.0 2.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME26414.1 - 6e-06 26.1 0.0 4.2e-05 23.3 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME26414.1 - 0.00088 18.8 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ORC2 PF04084.9 EME26415.1 - 7.7e-66 222.1 7.2 1.1e-65 221.6 5.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 B2-adapt-app_C PF09066.5 EME26415.1 - 0.041 13.7 2.4 6.6 6.6 0.1 3.3 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain Peptidase_M28 PF04389.12 EME26416.1 - 8.2e-31 107.1 0.0 1.3e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EME26416.1 - 0.0031 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 FYRN PF05964.9 EME26416.1 - 0.12 11.8 0.3 0.33 10.4 0.2 1.7 1 0 0 1 1 1 0 F/Y-rich N-terminus Epimerase PF01370.16 EME26417.1 - 1.8e-46 158.5 0.0 2.9e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME26417.1 - 4.7e-14 51.9 0.1 5.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EME26417.1 - 1.2e-12 47.1 0.0 1.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME26417.1 - 1.2e-11 44.0 0.7 1.3e-06 27.5 0.2 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME26417.1 - 3.4e-10 39.3 0.0 4.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME26417.1 - 1.4e-05 25.0 0.1 0.00012 22.0 0.0 2.2 1 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EME26417.1 - 0.00054 20.0 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EME26417.1 - 0.0069 16.0 0.0 0.027 14.1 0.0 1.9 3 0 0 3 3 3 1 KR domain HAD PF12710.2 EME26418.1 - 8.2e-16 58.7 0.1 1.5e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME26418.1 - 4.8e-13 49.2 0.1 4.7e-12 46.0 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 EME26418.1 - 5.2e-13 48.5 0.1 1.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain Hydrolase PF00702.21 EME26418.1 - 2.9e-08 34.4 0.0 8.7e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT PF01842.20 EME26418.1 - 0.00031 20.1 0.0 0.0013 18.1 0.0 2.1 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EME26418.1 - 0.0071 16.6 0.1 0.035 14.4 0.0 2.2 2 0 0 2 2 2 1 ACT domain DUF705 PF05152.7 EME26418.1 - 0.051 12.5 0.1 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) RRM_1 PF00076.17 EME26419.1 - 5.6e-11 41.9 0.0 9.4e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26419.1 - 0.0001 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26419.1 - 0.00038 20.2 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauE PF01925.14 EME26420.1 - 1.9e-16 60.2 33.0 4.5e-10 39.3 1.8 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2208 PF09973.4 EME26420.1 - 0.012 14.8 0.1 0.012 14.8 0.1 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) EB PF01683.13 EME26420.1 - 0.083 12.9 1.3 0.13 12.3 0.3 1.7 2 0 0 2 2 2 0 EB module DUF2306 PF10067.4 EME26420.1 - 0.1 12.7 0.3 0.1 12.7 0.2 3.8 3 2 0 3 3 3 0 Predicted membrane protein (DUF2306) RNase_P_Rpp14 PF01900.14 EME26421.1 - 1.7e-07 31.0 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family HD_4 PF13328.1 EME26422.1 - 0.0086 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 HD domain LURAP PF14854.1 EME26422.1 - 0.34 10.6 4.9 4.1 7.1 1.5 2.5 1 1 1 2 2 2 0 Leucine rich adaptor protein Rad17 PF03215.10 EME26423.1 - 2.4e-21 76.0 4.2 5.7e-19 68.2 0.8 2.4 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EME26423.1 - 1.5e-06 28.1 0.4 4.9e-06 26.4 0.3 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EME26423.1 - 2.6e-06 27.6 0.1 1.2e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EME26423.1 - 5.6e-06 25.6 1.0 3e-05 23.3 0.7 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EME26423.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EME26423.1 - 0.00012 21.9 0.4 0.00098 19.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EME26423.1 - 0.00012 22.3 0.1 0.0011 19.2 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EME26423.1 - 0.00016 21.8 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME26423.1 - 0.00033 20.5 0.0 0.00074 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME26423.1 - 0.0012 17.8 1.3 0.0032 16.3 0.9 1.9 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EME26423.1 - 0.0024 17.5 0.5 0.012 15.3 0.3 2.2 1 1 0 1 1 1 1 NACHT domain T2SE PF00437.15 EME26423.1 - 0.0029 16.5 0.0 0.0055 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_PrkA PF08298.6 EME26423.1 - 0.0052 15.5 0.0 0.014 14.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_24 PF13479.1 EME26423.1 - 0.0057 16.2 0.2 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME26423.1 - 0.0071 15.5 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EME26423.1 - 0.0075 15.9 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EME26423.1 - 0.01 16.1 0.1 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME26423.1 - 0.011 16.5 0.0 0.032 15.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME26423.1 - 0.013 15.7 0.1 0.062 13.4 0.0 2.3 2 0 0 2 2 1 0 RNA helicase PPV_E1_C PF00519.12 EME26423.1 - 0.02 13.5 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase MobB PF03205.9 EME26423.1 - 0.034 13.8 0.1 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EME26423.1 - 0.034 13.1 0.0 0.076 12.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 EME26423.1 - 0.036 14.5 1.0 0.13 12.7 0.1 2.4 2 1 0 2 2 2 0 Miro-like protein cobW PF02492.14 EME26423.1 - 0.037 13.4 2.6 0.063 12.7 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EME26423.1 - 0.044 13.4 0.2 0.09 12.4 0.2 1.6 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 EME26423.1 - 0.053 13.4 0.3 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain Rod-binding PF10135.4 EME26423.1 - 0.053 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Rod binding protein IstB_IS21 PF01695.12 EME26423.1 - 0.058 12.7 0.3 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EME26423.1 - 0.069 12.2 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 EME26423.1 - 0.1 12.1 4.5 4 6.9 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SMC_N PF02463.14 EME26423.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.10 EME26424.1 - 3.5e-21 75.4 4.4 8.1e-19 67.6 0.8 2.5 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EME26424.1 - 1.9e-06 27.7 0.3 5.6e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EME26424.1 - 3.5e-06 27.2 0.1 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EME26424.1 - 8e-06 25.1 1.0 3.9e-05 22.9 0.7 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EME26424.1 - 6e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EME26424.1 - 0.00015 22.0 0.0 0.0015 18.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 EME26424.1 - 0.00018 21.4 0.4 0.0012 18.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME26424.1 - 0.00019 21.5 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME26424.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME26424.1 - 0.0014 17.5 1.3 0.0038 16.1 0.9 1.8 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EME26424.1 - 0.0032 17.1 0.4 0.014 15.0 0.3 2.2 1 1 0 1 1 1 1 NACHT domain T2SE PF00437.15 EME26424.1 - 0.0035 16.2 0.0 0.0067 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_PrkA PF08298.6 EME26424.1 - 0.0067 15.1 0.0 0.017 13.8 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_24 PF13479.1 EME26424.1 - 0.0081 15.7 0.2 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME26424.1 - 0.0088 15.2 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EME26424.1 - 0.0099 15.6 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EME26424.1 - 0.011 15.8 0.0 0.074 13.2 0.0 2.5 2 0 0 2 2 1 0 RNA helicase AAA_17 PF13207.1 EME26424.1 - 0.012 16.4 0.0 0.039 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EME26424.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EME26424.1 - 0.04 13.6 0.1 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EME26424.1 - 0.044 12.8 0.0 0.092 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 EME26424.1 - 0.051 13.0 2.6 0.074 12.4 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EME26424.1 - 0.052 14.0 1.0 0.17 12.4 0.1 2.3 2 1 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 EME26424.1 - 0.053 13.2 0.2 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.1 EME26424.1 - 0.064 13.2 0.3 0.13 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain Rod-binding PF10135.4 EME26424.1 - 0.066 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Rod binding protein IstB_IS21 PF01695.12 EME26424.1 - 0.083 12.3 0.3 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EME26424.1 - 0.087 11.9 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 EME26424.1 - 0.13 11.8 4.2 4.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EBP PF05241.7 EME26425.1 - 4.9e-30 104.0 5.8 4.9e-30 104.0 4.0 1.4 2 0 0 2 2 2 1 Emopamil binding protein TRP PF06011.7 EME26425.1 - 0.043 12.4 1.9 0.048 12.2 1.3 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel NIF PF03031.13 EME26426.1 - 9.3e-53 178.1 0.0 2e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF-3c_N PF05470.7 EME26426.1 - 0.044 11.8 2.0 0.069 11.2 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NIF PF03031.13 EME26427.1 - 9.3e-53 178.1 0.0 2e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase eIF-3c_N PF05470.7 EME26427.1 - 0.044 11.8 2.0 0.069 11.2 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus 14-3-3 PF00244.15 EME26428.1 - 1.9e-107 357.7 8.3 2.3e-107 357.4 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF627 PF04781.7 EME26428.1 - 0.027 14.0 0.2 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_19 PF14559.1 EME26428.1 - 0.062 13.6 1.5 0.29 11.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Ferritin PF00210.19 EME26429.1 - 1.4e-34 118.8 1.6 2e-34 118.3 1.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Acatn PF13000.2 EME26430.1 - 6.8e-87 292.2 25.3 4.9e-57 193.7 8.8 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Acatn PF13000.2 EME26431.1 - 1.2e-89 301.3 28.8 5.1e-57 193.6 8.9 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Aldose_epim PF01263.15 EME26432.1 - 1.1e-41 142.9 0.0 1.3e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cpn60_TCP1 PF00118.19 EME26433.1 - 7.2e-142 473.4 10.3 8.3e-142 473.2 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PCI PF01399.22 EME26434.1 - 5.9e-13 49.0 1.8 1.8e-12 47.5 0.2 2.4 2 0 0 2 2 2 1 PCI domain PCI PF01399.22 EME26435.1 - 1.6e-13 50.9 1.4 6.1e-13 49.0 0.1 2.5 2 0 0 2 2 2 1 PCI domain Methyltransf_23 PF13489.1 EME26436.1 - 7.5e-13 48.5 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26436.1 - 7.8e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26436.1 - 4.5e-06 27.0 0.0 8.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26436.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26436.1 - 4e-05 23.8 0.0 6.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26436.1 - 0.00045 20.7 0.0 0.00079 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26436.1 - 0.019 14.9 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EME26436.1 - 0.14 11.1 0.0 0.34 9.8 0.0 1.6 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase SUI1 PF01253.17 EME26437.1 - 5.2e-16 58.2 0.1 8.5e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 ARID PF01388.16 EME26439.1 - 6e-25 86.9 0.0 2.9e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.1 EME26439.1 - 0.035 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Secretin_N_2 PF07655.8 EME26439.1 - 0.91 9.9 7.9 0.39 11.1 3.5 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain FMN_red PF03358.10 EME26440.1 - 3.1e-19 68.9 0.0 4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EME26440.1 - 1.7e-11 44.0 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EME26440.1 - 1.6e-09 37.9 0.1 3.8e-09 36.6 0.1 1.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 EME26440.1 - 0.00081 18.7 0.0 0.0017 17.7 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin S1 PF00575.18 EME26441.1 - 5.7e-30 103.2 0.2 3.3e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.1 EME26441.1 - 4.9e-08 32.7 0.1 0.00094 19.0 0.1 2.7 2 1 0 2 2 2 2 S1 domain CSD PF00313.17 EME26441.1 - 0.0077 15.9 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain Rcd1 PF04078.8 EME26442.1 - 2.2e-99 331.6 0.1 2.6e-99 331.3 0.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like ArfGap PF01412.13 EME26443.1 - 5e-41 139.1 0.0 5e-41 139.1 0.0 2.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 EME26443.1 - 6.5e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Z1 PF10593.4 EME26443.1 - 0.0057 15.8 2.5 0.012 14.8 1.7 1.5 1 0 0 1 1 1 1 Z1 domain UPF0139 PF03669.8 EME26444.1 - 1.8e-16 59.5 0.1 2.3e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Herpes_LMP2 PF07415.6 EME26444.1 - 0.0042 15.7 0.1 0.0046 15.5 0.0 1.0 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4149 PF13664.1 EME26444.1 - 0.036 14.1 0.4 0.042 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) CcoS PF03597.10 EME26444.1 - 2 7.9 0.0 2 7.9 0.0 2.8 3 1 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type EF-hand_7 PF13499.1 EME26445.1 - 6.6e-07 29.3 5.9 0.00011 22.2 0.4 4.9 3 2 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EME26445.1 - 1.2e-05 24.8 2.7 0.81 9.7 0.0 5.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 EME26445.1 - 0.00061 19.3 0.4 4.8 6.8 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EME26445.1 - 0.001 18.1 1.9 0.51 9.7 0.0 4.0 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 EME26445.1 - 0.017 14.4 0.2 0.066 12.5 0.1 2.1 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.4 EME26445.1 - 0.081 12.9 0.8 0.18 11.8 0.2 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Med26 PF08711.6 EME26446.1 - 9.9e-11 40.9 0.7 3.2e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain STAT_int PF02865.12 EME26446.1 - 0.12 12.3 2.0 0.8 9.6 0.0 2.7 2 1 0 2 2 2 0 STAT protein, protein interaction domain BURP PF03181.10 EME26446.1 - 0.16 11.1 0.6 0.35 9.9 0.4 1.5 1 0 0 1 1 1 0 BURP domain Abhydrolase_5 PF12695.2 EME26448.1 - 2.4e-23 82.4 0.0 3.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME26448.1 - 1.3e-17 64.4 0.0 8.8e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME26448.1 - 3.6e-12 45.4 0.1 4.6e-05 22.0 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EME26448.1 - 3.7e-10 39.7 0.0 2.2e-06 27.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME26448.1 - 3.6e-08 32.8 0.0 5.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EME26448.1 - 2.6e-06 27.1 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EME26448.1 - 2.6e-06 27.0 0.0 0.031 13.7 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EME26448.1 - 2.9e-05 23.8 0.0 0.019 14.6 0.0 2.5 2 1 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EME26448.1 - 0.00063 19.1 0.0 0.0031 16.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EME26448.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 EME26448.1 - 0.019 15.1 0.0 0.11 12.7 0.0 2.0 1 1 1 2 2 2 0 Thioesterase domain DUF818 PF05677.7 EME26448.1 - 0.032 12.9 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_4 PF08386.5 EME26448.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF1405 PF07187.6 EME26448.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) ATP-synt_Eps PF04627.8 EME26449.1 - 2e-17 62.4 0.4 2e-17 62.4 0.3 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain EF_TS PF00889.14 EME26450.1 - 6.9e-50 169.4 0.0 8.6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.26 EME26450.1 - 0.00095 18.9 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain MerR_1 PF13411.1 EME26450.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 MerR HTH family regulatory protein CENP-Q PF13094.1 EME26451.1 - 0.00071 19.6 6.2 0.00071 19.6 4.3 1.9 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.1 EME26451.1 - 0.00099 19.0 9.0 0.0018 18.2 6.2 1.3 1 0 0 1 1 1 1 Up-regulated During Septation ERM PF00769.14 EME26451.1 - 0.002 17.7 14.5 0.0028 17.2 10.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family IncA PF04156.9 EME26451.1 - 0.0033 17.0 12.0 0.0033 17.0 8.3 2.4 3 0 0 3 3 1 1 IncA protein HAUS5 PF14817.1 EME26451.1 - 0.0037 15.8 5.8 0.0049 15.4 4.0 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF3450 PF11932.3 EME26451.1 - 0.0041 16.4 2.2 0.0076 15.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Occludin_ELL PF07303.8 EME26451.1 - 0.0085 16.8 10.7 0.0085 16.8 7.4 1.8 1 1 0 1 1 1 1 Occludin homology domain DegS PF05384.6 EME26451.1 - 0.021 14.0 0.9 0.021 14.0 0.6 3.0 1 1 2 3 3 3 0 Sensor protein DegS DUF641 PF04859.7 EME26451.1 - 0.034 13.8 7.6 0.063 13.0 4.9 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF2339 PF10101.4 EME26451.1 - 0.04 12.2 1.3 0.066 11.4 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF95 PF01944.12 EME26451.1 - 0.057 13.0 6.2 0.25 10.9 2.2 2.9 2 1 1 3 3 3 0 Integral membrane protein DUF95 DUF1761 PF08570.5 EME26451.1 - 0.075 13.0 2.4 5.3 7.0 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) HemX PF04375.9 EME26451.1 - 0.084 11.4 4.0 0.12 10.9 2.8 1.2 1 0 0 1 1 1 0 HemX DUF1664 PF07889.7 EME26451.1 - 0.087 12.6 4.9 0.16 11.7 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3365 PF11845.3 EME26451.1 - 0.11 12.2 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF2031 PF09592.5 EME26451.1 - 0.12 11.5 9.2 0.26 10.4 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF87 PF01935.12 EME26451.1 - 0.17 11.6 4.6 0.26 11.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2968 PF11180.3 EME26451.1 - 0.19 11.0 7.5 0.33 10.3 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 EME26451.1 - 0.2 10.0 11.2 0.29 9.5 7.7 1.2 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.6 EME26451.1 - 0.2 11.0 9.5 0.25 10.6 6.1 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 EME26451.1 - 0.2 11.4 17.7 0.78 9.5 5.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Matrilin_ccoil PF10393.4 EME26451.1 - 0.23 10.8 5.1 1.9 7.8 0.6 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3373 PF11853.3 EME26451.1 - 0.24 9.8 10.0 0.87 8.0 6.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) ADIP PF11559.3 EME26451.1 - 0.25 11.2 12.9 0.1 12.5 3.3 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.3 EME26451.1 - 0.33 10.6 4.7 1.4 8.6 3.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4200 PF13863.1 EME26451.1 - 0.36 10.7 17.1 0.052 13.5 3.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EME26451.1 - 0.5 9.2 11.1 0.77 8.6 7.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF812 PF05667.6 EME26451.1 - 0.56 8.6 12.3 0.79 8.1 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Peptidase_S49_N PF08496.5 EME26451.1 - 0.85 9.3 12.3 0.031 14.0 4.0 2.0 2 0 0 2 2 1 0 Peptidase family S49 N-terminal DUF342 PF03961.8 EME26451.1 - 1.5 7.1 9.8 2 6.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 EME26451.1 - 1.6 8.6 9.9 1 9.3 1.8 2.3 1 1 1 2 2 2 0 FlxA-like protein TPX2 PF06886.6 EME26451.1 - 1.7 8.7 15.4 0.3 11.1 6.0 2.4 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) PilJ PF13675.1 EME26451.1 - 1.9 8.8 4.4 25 5.2 0.2 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term End3 PF12761.2 EME26451.1 - 2.3 7.8 12.2 3.6 7.1 8.5 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 EME26451.1 - 3.2 6.7 13.9 4.7 6.1 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EME26451.1 - 3.9 5.1 12.0 0.14 9.9 4.1 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EME26451.1 - 4.1 6.8 17.6 0.87 9.0 8.4 2.5 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 EME26451.1 - 4.4 6.8 12.3 10 5.6 2.6 2.8 1 1 1 2 2 2 0 Septum formation initiator Tropomyosin_1 PF12718.2 EME26451.1 - 4.4 7.1 20.4 1.3 8.8 6.0 2.2 1 1 1 2 2 2 0 Tropomyosin like ACCA PF03255.9 EME26451.1 - 4.5 6.8 7.4 3.1 7.3 2.8 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ribosomal_L29 PF00831.18 EME26451.1 - 5.3 6.8 15.8 2.4 7.8 1.0 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF3753 PF12575.3 EME26451.1 - 5.5 6.8 7.8 0.46 10.3 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Fib_alpha PF08702.5 EME26451.1 - 8.5 6.4 9.5 38 4.3 5.9 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tocopherol_cycl PF14249.1 EME26452.1 - 2.7e-91 305.7 4.0 3.2e-91 305.5 2.3 1.4 2 0 0 2 2 2 1 Tocopherol cyclase MoaC PF01967.16 EME26453.1 - 1.1e-50 170.8 1.3 1.3e-50 170.6 0.9 1.0 1 0 0 1 1 1 1 MoaC family DUF217 PF02697.9 EME26453.1 - 0.16 12.2 0.6 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Rieske PF00355.21 EME26454.1 - 2.4e-17 62.2 0.1 3.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EME26454.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Acetyltransf_1 PF00583.19 EME26455.1 - 3.3e-15 55.8 0.0 7.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME26455.1 - 6.5e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME26455.1 - 8.9e-07 29.0 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME26455.1 - 3.2e-06 27.3 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME26455.1 - 0.0056 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME26455.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 EME26455.1 - 0.02 14.7 0.0 0.11 12.3 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME26455.1 - 0.052 13.4 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EME26456.1 - 3.9e-85 286.1 23.0 5.1e-85 285.7 16.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26456.1 - 1.4e-31 109.5 30.6 5.1e-31 107.6 20.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily FixP_N PF14715.1 EME26456.1 - 0.16 11.3 4.3 0.072 12.4 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP PilX_N PF14341.1 EME26456.1 - 0.79 9.4 5.0 19 4.9 1.3 2.7 2 0 0 2 2 2 0 PilX N-terminal MFS_3 PF05977.8 EME26456.1 - 6.7 4.7 14.3 0.26 9.3 5.7 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_2 PF04550.7 EME26456.1 - 7.3 6.7 9.2 1.3 9.1 2.4 2.5 1 1 1 2 2 2 0 Phage holin family 2 Aminotran_1_2 PF00155.16 EME26457.1 - 7e-21 74.5 0.0 1.1e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 EME26458.1 - 1.5e-10 40.9 0.1 2.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.24 EME26461.1 - 4.2e-17 62.5 0.1 4.2e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EME26461.1 - 4e-15 55.5 0.1 1.7e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EME26461.1 - 1.3e-13 50.9 0.1 1.4e-09 37.8 0.0 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EME26461.1 - 8.6e-09 34.5 0.0 0.00021 20.1 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EME26461.1 - 5.6e-06 26.5 1.0 0.14 12.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain DNA_pol3_delta PF06144.8 EME26461.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EME26461.1 - 2.6e-05 24.2 0.0 0.0015 18.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EME26461.1 - 2.6e-05 23.9 0.0 5.1e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME26461.1 - 3.5e-05 22.9 0.0 6.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME26461.1 - 8.6e-05 22.2 0.0 0.00028 20.5 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EME26461.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EME26461.1 - 0.00059 19.3 0.1 0.013 14.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.8 EME26461.1 - 0.001 18.0 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EME26461.1 - 0.0016 17.9 0.5 0.025 14.0 0.3 2.6 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EME26461.1 - 0.0023 17.6 0.0 0.0085 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME26461.1 - 0.0023 17.3 0.4 0.041 13.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_3 PF07726.6 EME26461.1 - 0.0035 16.9 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EME26461.1 - 0.011 15.3 0.4 0.022 14.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EME26461.1 - 0.013 14.7 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EME26461.1 - 0.022 14.3 0.1 0.43 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain BRCT_assoc PF12820.2 EME26461.1 - 0.029 14.1 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT SNF2_N PF00176.18 EME26461.1 - 0.034 12.9 0.2 0.29 9.9 0.0 2.4 2 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_18 PF13238.1 EME26461.1 - 0.07 13.4 0.1 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME26461.1 - 0.08 13.7 0.3 0.34 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME26461.1 - 0.083 12.2 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 EME26461.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SAP PF02037.22 EME26463.1 - 5.7e-05 22.5 0.7 0.00015 21.1 0.1 2.0 2 0 0 2 2 2 1 SAP domain Abhydrolase_6 PF12697.2 EME26464.1 - 1.3e-19 70.9 0.0 2.4e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME26464.1 - 8.3e-14 51.6 0.0 1.8e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME26464.1 - 1.7e-11 44.0 0.0 6.9e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EME26464.1 - 0.0011 17.5 0.0 0.0016 16.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 EME26464.1 - 0.0068 15.8 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EME26464.1 - 0.16 11.4 0.0 2.8 7.3 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase (FSH1) WD40 PF00400.27 EME26465.1 - 7.2e-05 22.5 10.5 0.024 14.5 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF3312 PF11768.3 EME26465.1 - 0.0097 14.1 0.0 0.082 11.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 EME26465.1 - 0.069 12.9 0.1 0.78 9.5 0.0 2.4 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region UPF0118 PF01594.11 EME26466.1 - 3.4e-36 124.8 26.3 1.1e-29 103.4 12.9 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF20 Fucose_iso_C PF02952.12 EME26466.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain GCN5L1 PF06320.8 EME26467.1 - 3.2e-20 72.1 5.0 4.1e-20 71.8 3.5 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF1664 PF07889.7 EME26467.1 - 2.8e-05 23.9 1.4 3.9e-05 23.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EME26467.1 - 0.00057 19.7 0.2 0.00077 19.2 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EME26467.1 - 0.0014 18.3 3.1 0.002 17.8 1.8 1.4 1 1 0 1 1 1 1 Laminin Domain II Filament PF00038.16 EME26467.1 - 0.0028 17.1 5.2 0.0034 16.8 3.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein Apolipoprotein PF01442.13 EME26467.1 - 0.0031 17.0 1.5 0.0076 15.7 1.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.15 EME26467.1 - 0.0041 16.8 7.5 0.043 13.5 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prominin PF05478.6 EME26467.1 - 0.0042 14.7 0.7 0.0045 14.6 0.5 1.0 1 0 0 1 1 1 1 Prominin NPV_P10 PF05531.7 EME26467.1 - 0.0051 17.0 1.3 0.041 14.1 0.0 2.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Cast PF10174.4 EME26467.1 - 0.0078 14.3 5.0 0.0089 14.1 3.4 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF1340 PF07067.6 EME26467.1 - 0.008 15.3 0.1 0.016 14.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1340) Prefoldin PF02996.12 EME26467.1 - 0.0086 15.7 5.0 0.13 11.8 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF4618 PF15397.1 EME26467.1 - 0.0093 15.3 3.9 0.011 15.1 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) COG5 PF10392.4 EME26467.1 - 0.0094 15.9 3.6 0.087 12.7 0.1 2.0 1 1 0 2 2 2 1 Golgi transport complex subunit 5 DUF948 PF06103.6 EME26467.1 - 0.016 15.0 2.3 2 8.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EME26467.1 - 0.018 13.5 2.9 0.021 13.2 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Val_tRNA-synt_C PF10458.4 EME26467.1 - 0.019 15.0 6.9 0.21 11.7 1.4 2.6 2 1 1 3 3 2 0 Valyl tRNA synthetase tRNA binding arm YtxH PF12732.2 EME26467.1 - 0.02 15.2 2.4 0.029 14.7 1.7 1.4 1 1 0 1 1 1 0 YtxH-like protein DUF632 PF04782.7 EME26467.1 - 0.021 13.9 3.8 0.024 13.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF632) PEP-utilisers_N PF05524.8 EME26467.1 - 0.026 14.3 1.9 1.2 8.9 0.1 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PhaP_Bmeg PF09602.5 EME26467.1 - 0.039 13.7 3.8 0.053 13.3 2.6 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF883 PF05957.8 EME26467.1 - 0.04 14.3 0.2 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 EME26467.1 - 0.041 12.3 3.8 0.042 12.3 2.6 1.1 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.7 EME26467.1 - 0.048 13.5 5.4 0.16 11.9 0.2 2.5 2 1 0 3 3 2 0 MbeD/MobD like COG2 PF06148.6 EME26467.1 - 0.05 13.4 2.1 0.27 11.0 1.5 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF489 PF04356.7 EME26467.1 - 0.056 13.0 2.8 0.9 9.0 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) V_ATPase_I PF01496.14 EME26467.1 - 0.059 11.2 3.2 0.089 10.6 2.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2163 PF09931.4 EME26467.1 - 0.065 13.0 0.1 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DUF1319 PF07028.6 EME26467.1 - 0.066 13.4 3.8 0.8 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Spc24 PF08286.6 EME26467.1 - 0.075 12.7 6.2 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SpvB PF03534.8 EME26467.1 - 0.077 12.0 0.7 0.087 11.8 0.5 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Tektin PF03148.9 EME26467.1 - 0.083 11.4 8.2 0.057 11.9 0.4 2.2 1 1 1 3 3 3 0 Tektin family FliD_C PF07195.7 EME26467.1 - 0.088 12.0 1.3 0.11 11.7 0.9 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus EF1G PF00647.14 EME26467.1 - 0.09 12.4 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Phasin PF05597.6 EME26467.1 - 0.098 12.4 5.2 0.075 12.8 2.3 1.7 2 1 0 2 2 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BLOC1_2 PF10046.4 EME26467.1 - 0.1 12.7 5.6 1.2 9.3 0.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc42p PF11544.3 EME26467.1 - 0.11 12.3 3.3 7 6.6 0.6 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p Terminase_2 PF03592.11 EME26467.1 - 0.13 12.5 1.8 0.15 12.3 1.2 1.1 1 0 0 1 1 1 0 Terminase small subunit CorA PF01544.13 EME26467.1 - 0.14 11.1 1.7 0.16 10.9 1.2 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EME26467.1 - 0.14 11.6 7.2 0.26 10.8 5.0 1.4 1 1 0 1 1 1 0 IncA protein WXG100 PF06013.7 EME26467.1 - 0.17 11.9 2.5 20 5.2 0.0 2.7 1 1 1 3 3 3 0 Proteins of 100 residues with WXG FliJ PF02050.11 EME26467.1 - 0.18 11.8 6.2 0.28 11.2 4.3 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.17 EME26467.1 - 0.18 11.8 6.1 3.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec2p PF06428.6 EME26467.1 - 0.18 11.6 6.6 0.23 11.3 4.6 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Peptidase_M16 PF00675.15 EME26467.1 - 0.19 11.4 1.9 0.22 11.2 0.7 1.5 1 1 0 1 1 1 0 Insulinase (Peptidase family M16) SLA_LP_auto_ag PF05889.8 EME26467.1 - 0.21 10.0 0.9 0.25 9.7 0.6 1.3 1 1 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) SF-assemblin PF06705.6 EME26467.1 - 0.21 10.6 5.3 1.2 8.2 3.7 1.9 1 1 0 1 1 1 0 SF-assemblin/beta giardin MEF2_binding PF09047.5 EME26467.1 - 0.21 11.2 2.9 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 MEF2 binding FlaC_arch PF05377.6 EME26467.1 - 0.31 10.9 0.2 0.31 10.9 0.1 2.7 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) NUMOD3 PF07460.6 EME26467.1 - 0.32 10.9 2.1 16 5.4 0.0 2.3 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) DUF3688 PF12461.3 EME26467.1 - 0.32 11.3 2.5 1.3 9.4 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3688) DASH_Dad3 PF08656.5 EME26467.1 - 0.33 10.6 5.4 0.66 9.7 0.3 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad3 DUF4164 PF13747.1 EME26467.1 - 0.38 10.9 3.6 1.9 8.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TBPIP PF07106.8 EME26467.1 - 0.38 10.2 8.9 0.21 11.0 0.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Occludin_ELL PF07303.8 EME26467.1 - 0.44 11.2 3.3 9.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF4404 PF14357.1 EME26467.1 - 0.54 10.7 3.4 1.2 9.6 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Phage_GP20 PF06810.6 EME26467.1 - 0.74 9.2 7.7 4.1 6.8 2.7 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 APG6 PF04111.7 EME26467.1 - 0.79 8.7 7.0 1 8.3 4.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 EME26467.1 - 0.86 9.9 4.4 2.3 8.6 0.1 2.2 1 1 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.7 EME26467.1 - 1 9.7 3.9 2 8.8 0.1 2.4 2 1 0 2 2 2 0 SlyX Tropomyosin_1 PF12718.2 EME26467.1 - 1.1 9.1 10.0 0.38 10.6 0.4 2.0 1 1 0 1 1 1 0 Tropomyosin like PCRF PF03462.13 EME26467.1 - 1.4 8.6 5.1 1.3 8.7 0.9 2.1 1 1 1 2 2 2 0 PCRF domain ADIP PF11559.3 EME26467.1 - 1.5 8.6 8.6 0.6 10.0 0.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EME26467.1 - 1.9 8.9 6.1 10 6.5 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 EME26467.1 - 2.1 8.1 7.5 2 8.2 0.1 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-Q PF13094.1 EME26467.1 - 2.3 8.2 8.5 1.6 8.7 0.4 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EME26467.1 - 2.8 7.7 11.8 3 7.6 0.3 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 EME26468.1 - 8.2e-70 234.9 0.0 1.4e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26468.1 - 3.9e-51 173.6 0.0 6.8e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26468.1 - 4.1e-07 29.2 0.0 4.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME26468.1 - 0.0018 18.0 0.0 0.93 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME26468.1 - 0.013 14.6 0.0 0.031 13.3 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EME26469.1 - 8.2e-70 234.9 0.0 1.4e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26469.1 - 3.9e-51 173.6 0.0 6.8e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26469.1 - 4.1e-07 29.2 0.0 4.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME26469.1 - 0.0018 18.0 0.0 0.93 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME26469.1 - 0.013 14.6 0.0 0.031 13.3 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAP59_mtransfer PF11735.3 EME26470.1 - 9.6e-43 146.1 0.2 1.3e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 3-HAO PF06052.7 EME26471.1 - 3.1e-55 185.7 0.0 3.7e-55 185.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EME26471.1 - 6.9e-05 22.2 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.1 EME26471.1 - 0.0065 16.1 1.9 0.27 10.9 0.2 2.5 2 0 0 2 2 2 1 Nudix N-terminal AraC_binding PF02311.14 EME26471.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.17 EME26471.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin DZR PF12773.2 EME26471.1 - 0.59 9.9 2.7 2.4 8.0 0.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon 3-HAO PF06052.7 EME26472.1 - 4.6e-51 172.1 0.1 3.2e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Nudix_N_2 PF14803.1 EME26472.1 - 0.0082 15.8 1.9 0.3 10.8 0.2 2.5 2 0 0 2 2 2 1 Nudix N-terminal Cupin_2 PF07883.6 EME26472.1 - 0.1 12.0 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Cupin domain DZR PF12773.2 EME26472.1 - 0.67 9.8 2.5 2.6 7.9 0.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon Aminotran_5 PF00266.14 EME26473.1 - 4.5e-12 45.3 0.0 5.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME26473.1 - 0.11 11.5 0.0 0.32 9.9 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DNA_pol_E_B PF04042.11 EME26474.1 - 2.6e-24 85.6 1.3 5.3e-24 84.6 0.9 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EME26474.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal CholecysA-Rec_N PF09193.5 EME26474.1 - 0.056 13.3 0.5 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 Cholecystokinin A receptor, N-terminal Metallophos_3 PF14582.1 EME26474.1 - 0.056 12.5 0.0 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Ribosomal_S8e PF01201.17 EME26475.1 - 6.7e-37 126.5 2.2 2.1e-36 124.9 1.5 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Vir_act_alpha_C PF10400.4 EME26475.1 - 0.18 12.1 2.3 0.34 11.2 1.1 1.9 1 1 0 1 1 1 0 Virulence activator alpha C-term TspO_MBR PF03073.10 EME26476.1 - 1.7e-28 98.9 13.5 2.1e-28 98.6 9.4 1.1 1 0 0 1 1 1 1 TspO/MBR family Cys_Met_Meta_PP PF01053.15 EME26477.1 - 3.1e-119 397.7 0.0 3.8e-119 397.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EME26477.1 - 4.3e-05 22.4 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME26477.1 - 0.0002 20.5 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EME26477.1 - 0.03 12.6 0.0 0.38 9.0 0.0 2.0 2 0 0 2 2 2 0 Methionine gamma-lyase SelA PF03841.8 EME26477.1 - 0.054 12.2 0.0 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase SMK-1 PF04802.10 EME26478.1 - 2.1e-27 95.8 9.0 5.7e-27 94.4 6.3 1.8 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 MCM PF00493.18 EME26479.1 - 3.6e-135 450.0 0.2 5e-135 449.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME26479.1 - 1.6e-20 73.8 0.2 1.3e-19 70.8 0.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME26479.1 - 1.9e-06 27.1 0.3 0.00022 20.4 0.0 3.3 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EME26479.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME26479.1 - 0.015 15.0 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4332 PF14229.1 EME26479.1 - 0.03 14.3 0.6 0.15 12.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) Mg_chelatase_2 PF13335.1 EME26479.1 - 0.033 14.5 0.9 0.13 12.7 0.7 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME26479.1 - 0.067 12.6 0.1 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EME26479.1 - 0.17 11.8 4.1 5.8 6.8 0.3 3.8 3 2 1 5 5 5 0 AAA ATPase domain ATP-synt_ab PF00006.20 EME26480.1 - 6.6e-108 359.1 0.0 1e-107 358.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME26480.1 - 9.2e-23 80.8 0.8 2.6e-22 79.4 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Phos_pyr_kin PF08543.7 EME26480.1 - 6.6e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ATP-synt_ab_N PF02874.18 EME26480.1 - 3.8e-14 52.6 1.2 3.8e-14 52.6 0.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain PfkB PF00294.19 EME26480.1 - 3.5e-10 39.5 0.6 1.4e-08 34.2 0.0 2.8 3 0 0 3 3 3 1 pfkB family carbohydrate kinase ATP-synt_ab PF00006.20 EME26481.1 - 6.4e-108 359.1 0.0 1e-107 358.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME26481.1 - 8.2e-23 81.0 0.8 2.6e-22 79.4 0.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Phos_pyr_kin PF08543.7 EME26481.1 - 7.6e-15 54.7 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ATP-synt_ab_N PF02874.18 EME26481.1 - 3.7e-14 52.6 1.2 3.7e-14 52.6 0.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain PfkB PF00294.19 EME26481.1 - 8.3e-11 41.5 0.6 3.6e-09 36.1 0.0 2.8 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Symplekin_C PF12295.3 EME26482.1 - 3.5e-48 163.9 1.8 3.5e-48 163.9 1.3 4.2 5 1 1 6 6 6 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EME26482.1 - 3.2e-12 46.3 6.7 3.2e-12 46.3 4.7 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) HeH PF12949.2 EME26482.1 - 0.00014 21.3 1.5 0.00075 18.9 0.0 3.0 3 0 0 3 3 3 1 HeH/LEM domain FPN1 PF06963.7 EME26483.1 - 1.4e-57 195.0 22.8 1.7e-57 194.7 15.8 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) 60KD_IMP PF02096.15 EME26484.1 - 5.1e-27 94.8 1.2 7.7e-27 94.2 0.8 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein OAD_gamma PF04277.8 EME26484.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_C97 PF05903.9 EME26486.1 - 1.6e-35 122.0 0.0 2.3e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Ras PF00071.17 EME26487.1 - 1.5e-66 222.7 1.8 1.8e-66 222.4 1.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME26487.1 - 3e-22 79.3 0.0 6.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME26487.1 - 1.6e-18 66.5 0.2 2.2e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME26487.1 - 6e-07 28.8 0.1 7.7e-07 28.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EME26487.1 - 3.3e-06 26.4 0.1 4.6e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EME26487.1 - 2.3e-05 24.3 0.2 9.5e-05 22.3 0.1 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME26487.1 - 6.9e-05 22.3 0.5 0.00015 21.2 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EME26487.1 - 0.00033 19.8 0.2 0.0015 17.7 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME26487.1 - 0.00042 20.4 0.0 0.0011 19.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EME26487.1 - 0.00051 20.2 0.4 0.14 12.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EME26487.1 - 0.0063 15.7 0.2 0.05 12.8 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EME26487.1 - 0.0098 15.8 0.1 0.062 13.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EME26487.1 - 0.013 15.1 0.1 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EME26487.1 - 0.016 14.8 0.8 1.4 8.4 0.0 2.6 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.4 EME26487.1 - 0.037 13.5 0.2 0.37 10.2 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EME26487.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EME26487.1 - 0.083 13.1 0.3 0.18 12.0 0.2 1.8 1 1 0 1 1 1 0 ABC transporter IL28A PF15177.1 EME26487.1 - 0.1 12.0 0.2 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Interleukin-28A cwf21 PF08312.7 EME26488.1 - 8.9e-05 22.2 7.8 8.9e-05 22.2 5.4 3.2 4 1 0 4 4 4 1 cwf21 domain DUF1202 PF06717.6 EME26488.1 - 0.19 10.9 6.2 0.28 10.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) DEAD PF00270.24 EME26489.1 - 1.1e-39 135.6 0.1 2.6e-39 134.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME26489.1 - 9.7e-29 99.0 0.6 3.3e-28 97.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EME26489.1 - 3.6e-05 23.4 0.5 8.6e-05 22.2 0.2 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME26489.1 - 4.3e-05 23.1 0.0 9.8e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EME26489.1 - 4.8e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME26489.1 - 0.00025 21.1 0.0 0.00056 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SecA_DEAD PF07517.9 EME26489.1 - 0.00087 18.6 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain NACHT PF05729.7 EME26489.1 - 0.0019 17.8 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Helicase_C_2 PF13307.1 EME26489.1 - 0.003 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain PhoH PF02562.11 EME26489.1 - 0.034 13.3 0.8 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein tRNA-synt_1b PF00579.20 EME26489.1 - 0.053 12.6 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 EME26489.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HSP70 PF00012.15 EME26490.1 - 5.6e-146 486.9 5.8 1.6e-143 478.7 2.6 3.0 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.8 EME26490.1 - 3.1e-13 49.0 0.0 6.1e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein B5 PF03484.10 EME26490.1 - 0.03 14.1 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase B5 domain DUF2757 PF10955.3 EME26490.1 - 0.085 13.0 2.1 39 4.5 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2757) Peptidase_M22 PF00814.20 EME26491.1 - 2.7e-36 125.4 0.0 3.9e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family Ribosomal_S11 PF00411.14 EME26491.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S11 WD40 PF00400.27 EME26492.1 - 1.1e-31 107.4 22.0 1e-08 34.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_S10 PF00338.17 EME26493.1 - 1.8e-25 88.6 0.0 2.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1 PF00133.17 EME26494.1 - 4.6e-63 213.1 0.0 4e-46 157.2 0.0 4.4 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EME26494.1 - 1.1e-50 171.5 0.0 2e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EME26494.1 - 3.3e-29 101.7 0.0 2.9e-20 72.2 0.0 3.2 2 1 1 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EME26494.1 - 5.4e-18 65.2 1.4 2.8e-17 62.8 1.0 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EME26494.1 - 0.00039 19.6 0.0 0.048 12.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Abi PF02517.11 EME26495.1 - 9.5e-07 28.8 1.7 9.5e-07 28.8 1.2 3.1 2 1 0 2 2 2 1 CAAX protease self-immunity tRNA_int_endo PF01974.12 EME26496.1 - 2.3e-18 65.7 0.0 4.1e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Prp18 PF02840.10 EME26498.1 - 1.3e-55 187.2 0.9 1.3e-55 187.2 0.6 2.0 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EME26498.1 - 1.4e-11 43.4 0.3 1.4e-11 43.4 0.2 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like HHA PF05321.6 EME26498.1 - 0.022 14.8 1.0 24 5.1 0.0 3.8 3 0 0 3 3 3 0 Haemolysin expression modulating protein Mitofilin PF09731.4 EME26499.1 - 1.4e-43 149.5 39.0 5.4e-43 147.5 27.0 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein zf-C3HC4_2 PF13923.1 EME26501.1 - 2.4 8.2 20.5 0.28 11.2 10.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME26502.1 - 0.59 9.8 10.0 3.1 7.5 6.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EME26502.1 - 0.84 9.4 7.8 0.86 9.4 3.6 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF382 PF04037.8 EME26503.1 - 1.1e-57 193.3 2.2 1.1e-57 193.3 1.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 EME26503.1 - 9.2e-22 76.1 5.6 2.8e-21 74.6 3.9 1.9 1 0 0 1 1 1 1 PSP Nnf1 PF03980.9 EME26504.1 - 2.8e-06 27.2 7.1 4.3e-06 26.6 4.9 1.3 1 0 0 1 1 1 1 Nnf1 DUF972 PF06156.8 EME26504.1 - 0.028 14.7 4.1 0.099 12.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4472 PF14739.1 EME26504.1 - 0.059 13.8 7.8 0.71 10.3 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF1826 PF08856.6 EME26504.1 - 0.088 12.5 2.6 0.53 10.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) bZIP_Maf PF03131.12 EME26504.1 - 0.18 12.1 6.4 0.076 13.3 2.0 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TACC PF05010.9 EME26504.1 - 0.46 10.2 7.3 3.3 7.4 5.1 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) AAA_16 PF13191.1 EME26509.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DER1 PF04511.10 EME26511.1 - 1.3e-49 168.3 11.5 1.5e-49 168.1 7.9 1.0 1 0 0 1 1 1 1 Der1-like family Nop52 PF05997.7 EME26512.1 - 1.3e-31 109.7 3.1 1.8e-31 109.2 2.2 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Fer2 PF00111.22 EME26513.1 - 4.6e-15 55.1 0.6 7.3e-15 54.4 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Amidase PF01425.16 EME26513.1 - 0.06 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Amidase Fer2_4 PF13510.1 EME26513.1 - 0.082 12.7 1.2 0.61 9.9 0.8 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain VRP1 PF03538.9 EME26513.1 - 0.084 11.9 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein AAA_22 PF13401.1 EME26514.1 - 1.6e-10 41.1 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EME26514.1 - 2e-09 37.7 0.0 6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME26514.1 - 5.5e-08 33.0 0.1 2.6e-06 27.5 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EME26514.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EME26514.1 - 4.4e-05 22.6 0.1 0.015 14.2 0.0 2.2 1 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EME26514.1 - 0.0014 17.6 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EME26514.1 - 0.012 14.4 1.4 0.45 9.3 0.0 2.9 3 1 1 4 4 4 0 NB-ARC domain Sigma54_activat PF00158.21 EME26514.1 - 0.03 13.8 0.1 0.067 12.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 EME26514.1 - 0.033 13.1 0.0 0.081 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activ_2 PF14532.1 EME26514.1 - 0.062 13.3 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NifU PF01106.12 EME26515.1 - 4.8e-31 106.3 0.4 1.1e-24 85.9 0.1 2.2 2 0 0 2 2 2 2 NifU-like domain TIP49 PF06068.8 EME26516.1 - 1e-180 600.7 0.0 1.4e-180 600.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EME26516.1 - 9.8e-11 41.1 2.5 1.1e-05 24.6 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EME26516.1 - 3.2e-09 37.0 0.2 1.7e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME26516.1 - 2.5e-05 24.3 0.1 0.062 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EME26516.1 - 0.00033 20.7 0.1 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.10 EME26516.1 - 0.00087 18.2 0.0 0.0027 16.6 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 EME26516.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME26516.1 - 0.0022 17.8 0.0 3.1 7.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EME26516.1 - 0.004 16.8 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EME26516.1 - 0.0056 16.4 0.1 3.6 7.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME26516.1 - 0.022 13.8 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME26516.1 - 0.04 13.3 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EME26516.1 - 0.046 12.8 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TFIID-31kDa PF02291.10 EME26516.1 - 0.071 12.8 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AAA_28 PF13521.1 EME26516.1 - 0.086 12.8 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME26516.1 - 0.11 13.2 0.1 0.28 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Pol_alpha_B_N PF08418.5 EME26517.1 - 7.2 6.0 25.4 0.62 9.5 9.2 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal IMPDH PF00478.20 EME26519.1 - 3.9e-134 446.9 0.6 4.5e-134 446.7 0.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EME26519.1 - 2.3e-16 59.2 0.0 4.8e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EME26519.1 - 1.1e-12 47.8 1.3 1.6e-07 30.7 0.4 2.5 2 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 EME26519.1 - 9.9e-07 27.9 0.1 2e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EME26519.1 - 0.00098 18.4 0.1 0.0034 16.6 0.1 2.0 2 1 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 EME26519.1 - 0.0011 17.9 1.8 0.018 13.9 0.2 2.4 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DUF561 PF04481.7 EME26519.1 - 0.0072 15.3 0.6 0.4 9.5 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF561) ThiG PF05690.9 EME26519.1 - 0.011 14.7 0.5 0.055 12.5 0.3 2.1 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EME26519.1 - 0.23 10.7 1.9 12 5.1 0.0 3.6 4 1 1 5 5 5 0 PcrB family tRNA-synt_2b PF00587.20 EME26520.1 - 2.1e-33 115.3 0.0 3.6e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EME26520.1 - 5.8e-16 58.4 4.2 8.7e-16 57.8 2.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EME26520.1 - 0.002 17.2 1.1 0.029 13.4 1.3 2.0 2 0 0 2 2 2 1 Autophagy protein Apg6 FlgN PF05130.7 EME26520.1 - 0.0087 16.3 1.8 0.016 15.4 1.2 1.3 1 0 0 1 1 1 1 FlgN protein tRNA-synt_2d PF01409.15 EME26520.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) FlxA PF14282.1 EME26520.1 - 0.065 13.1 8.1 0.11 12.4 5.6 1.3 1 0 0 1 1 1 0 FlxA-like protein XhlA PF10779.4 EME26520.1 - 0.32 10.9 6.4 0.59 10.0 4.5 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Trm112p PF03966.11 EME26521.1 - 9.3e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Trm112p-like protein PAXNEB PF05625.6 EME26522.1 - 2.9e-48 164.5 0.0 3.2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein CDC45 PF02724.9 EME26523.1 - 4.3e-84 282.7 4.6 1.4e-82 277.7 3.2 2.3 1 1 0 1 1 1 1 CDC45-like protein FMN_dh PF01070.13 EME26525.1 - 1.7e-134 448.2 0.7 1.9e-134 447.9 0.5 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME26525.1 - 0.00022 20.2 1.6 0.0014 17.6 1.0 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EME26525.1 - 0.00038 19.4 0.2 0.00055 18.9 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EME26525.1 - 0.001 18.1 1.6 0.013 14.5 0.1 2.3 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EME26525.1 - 0.072 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase NMO PF03060.10 EME26525.1 - 0.079 12.0 0.9 0.14 11.2 0.6 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Peptidase_M19 PF01244.16 EME26525.1 - 0.084 11.7 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Polyketide_cyc PF03364.15 EME26526.1 - 2.7e-13 50.0 0.9 4.5e-13 49.3 0.6 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EME26526.1 - 2e-10 40.9 0.1 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RabGAP-TBC PF00566.13 EME26527.1 - 1.5e-29 102.9 1.4 2.1e-29 102.5 1.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4149 PF13664.1 EME26528.1 - 6.8 6.8 7.0 1.2 9.2 1.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) Mpv17_PMP22 PF04117.7 EME26530.1 - 8.3e-24 83.0 5.3 8.1e-23 79.8 0.6 2.2 1 1 1 2 2 2 2 Mpv17 / PMP22 family Glyco_hydro_14 PF01373.12 EME26531.1 - 2.7e-79 266.7 0.0 3.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 ATP_bind_3 PF01171.15 EME26531.1 - 0.0058 16.1 0.2 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 PP-loop family Glyco_hydro_14 PF01373.12 EME26532.1 - 2.7e-79 266.7 0.0 3.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 ATP_bind_3 PF01171.15 EME26532.1 - 0.0058 16.1 0.2 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 PP-loop family Ferrochelatase PF00762.14 EME26533.1 - 1.6e-91 306.5 0.0 2.4e-91 305.9 0.0 1.3 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 EME26533.1 - 1.5e-06 28.2 0.0 0.0008 19.4 0.0 2.8 2 1 0 2 2 2 2 CbiX Esterase PF00756.15 EME26534.1 - 2.1e-53 181.3 0.0 2.6e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EME26534.1 - 1.7e-07 30.7 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME26534.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME26534.1 - 0.00013 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME26534.1 - 0.0056 15.5 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EME26534.1 - 0.0095 15.8 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME26534.1 - 0.031 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EME26534.1 - 0.042 13.1 0.0 0.16 11.2 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EME26534.1 - 0.06 12.9 0.0 0.3 10.6 0.0 1.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EME26534.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DAGK_acc PF00609.14 EME26535.1 - 1.6e-27 96.6 0.0 2.5e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EME26535.1 - 1.3e-19 69.9 0.0 1.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain YEATS PF03366.11 EME26536.1 - 1.6e-27 95.0 0.1 2.5e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 YEATS family Syntaxin-6_N PF09177.6 EME26537.1 - 0.0047 17.2 3.3 0.0076 16.6 0.3 2.6 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Sec23_helical PF04815.10 EME26537.1 - 0.032 13.6 4.7 0.32 10.4 0.2 3.4 2 1 2 4 4 4 0 Sec23/Sec24 helical domain Snf7 PF03357.16 EME26537.1 - 0.054 12.8 1.1 0.12 11.8 0.8 1.5 1 0 0 1 1 1 0 Snf7 TPX2 PF06886.6 EME26537.1 - 0.091 12.8 1.7 0.24 11.4 1.2 1.7 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DUF2309 PF10070.4 EME26538.1 - 0.003 15.7 1.2 0.0043 15.2 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) FUSC PF04632.7 EME26540.1 - 1.9e-05 23.3 26.6 0.00018 20.0 5.5 2.5 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 EME26540.1 - 0.086 11.4 9.2 0.013 14.1 0.8 2.8 3 0 0 3 3 3 0 Aluminium activated malate transporter AAA_11 PF13086.1 EME26541.1 - 5.2e-31 108.0 0.0 8.6e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EME26541.1 - 8.7e-26 90.5 0.0 1.8e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME26541.1 - 5e-10 38.9 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME26541.1 - 3.2e-05 23.6 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME26541.1 - 0.00074 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EME26541.1 - 0.0011 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EME26541.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EME26541.1 - 0.015 14.5 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EME26541.1 - 0.017 15.2 0.0 0.084 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME26541.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME26541.1 - 0.036 14.8 0.0 3.1 8.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EME26541.1 - 0.064 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.24 EME26541.1 - 0.16 11.4 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase RecA PF00154.16 EME26541.1 - 0.37 9.8 0.0 0.58 9.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Tim44 PF04280.10 EME26542.1 - 3.8e-08 33.4 0.1 8.3e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Tim44-like domain SAM_2 PF07647.12 EME26546.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2461 PF09365.5 EME26546.1 - 0.07 12.5 0.2 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) Pro_isomerase PF00160.16 EME26547.1 - 1e-43 149.2 0.1 1.5e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EME26547.1 - 1.5e-11 43.7 0.0 2.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26547.1 - 3e-08 33.5 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26547.1 - 8.5e-08 31.9 0.1 2.2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S-AdoMet_synt_C PF02773.11 EME26548.1 - 5.1e-74 246.5 0.1 7.7e-74 245.9 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EME26548.1 - 7.8e-48 161.3 0.0 1.4e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EME26548.1 - 1.6e-41 140.5 0.2 3.1e-41 139.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Sugar_tr PF00083.19 EME26549.1 - 7.1e-83 278.6 23.2 8.6e-83 278.3 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26549.1 - 3.7e-30 104.8 26.5 3.7e-30 104.8 18.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EME26549.1 - 0.092 12.7 13.3 0.27 11.2 0.4 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Tweety PF04906.8 EME26549.1 - 0.12 10.7 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Tweety Furin-like PF00757.15 EME26551.1 - 1.3e-05 24.8 35.4 0.0052 16.4 9.0 3.9 1 1 1 3 3 3 2 Furin-like cysteine rich region Fer4_3 PF12798.2 EME26551.1 - 2.9 8.6 40.3 1.8 9.3 0.2 8.0 6 2 0 6 6 6 0 4Fe-4S binding domain OCIA PF07051.6 EME26552.1 - 0.0045 16.3 0.0 0.0099 15.2 0.0 1.6 1 1 0 1 1 1 1 Ovarian carcinoma immunoreactive antigen (OCIA) E1-E2_ATPase PF00122.15 EME26553.1 - 1.1e-45 155.4 2.2 1.1e-45 155.4 1.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EME26553.1 - 1.1e-35 123.9 0.0 4.4e-35 122.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME26553.1 - 5.3e-14 52.8 0.0 5.5e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME26553.1 - 0.00013 21.6 0.1 0.00031 20.4 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rifin_STEVOR PF02009.11 EME26553.1 - 0.072 12.7 0.4 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Rifin/stevor family DUF2839 PF10999.3 EME26554.1 - 0.052 13.5 0.4 0.09 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Snf7 PF03357.16 EME26555.1 - 1.1e-20 73.7 16.8 1.1e-20 73.7 11.6 1.4 1 1 0 1 1 1 1 Snf7 Rad33 PF08730.5 EME26555.1 - 0.0079 15.6 4.3 0.011 15.1 3.0 1.2 1 0 0 1 1 1 1 Rad33 MutS_III PF05192.13 EME26555.1 - 0.31 10.7 6.0 0.28 10.9 3.2 1.6 1 1 0 1 1 1 0 MutS domain III YlqD PF11068.3 EME26555.1 - 0.36 10.8 18.4 0.041 13.9 6.9 2.4 1 1 0 2 2 2 0 YlqD protein Flu_NS2 PF00601.14 EME26555.1 - 0.99 9.6 12.9 1.9 8.7 3.2 2.4 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) CCT PF06203.9 EME26556.1 - 8e-17 60.5 10.8 8e-17 60.5 7.5 1.8 1 1 1 2 2 2 1 CCT motif CCT_2 PF09425.5 EME26556.1 - 0.012 15.1 1.0 0.032 13.7 0.7 1.7 1 0 0 1 1 1 0 Divergent CCT motif Ribosomal_L18p PF00861.17 EME26557.1 - 1.3e-07 31.8 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L18p/L5e family CoA_binding_3 PF13727.1 EME26557.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Zip PF02535.17 EME26558.1 - 1.2e-43 149.3 10.8 2.2e-43 148.4 7.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EME26558.1 - 0.26 10.5 11.6 0.24 10.6 4.5 2.4 2 1 0 2 2 2 0 HupE / UreJ protein SepZ PF06066.6 EME26558.1 - 0.86 9.6 4.5 0.23 11.4 0.4 2.0 2 1 0 2 2 2 0 SepZ DEAD PF00270.24 EME26559.1 - 1e-33 116.1 0.1 1e-33 116.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME26559.1 - 3.9e-23 81.1 0.6 2.1e-22 78.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EME26559.1 - 0.00022 21.2 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EME26559.1 - 0.0011 18.7 3.9 0.0018 18.1 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME26559.1 - 0.0038 17.3 0.0 0.02 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EME26559.1 - 0.029 13.4 2.2 0.09 11.8 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Lactamase_B PF00753.22 EME26560.1 - 7.1e-21 74.7 0.0 9.4e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME26560.1 - 3.7e-05 23.3 0.0 7.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Grp1_Fun34_YaaH PF01184.14 EME26561.1 - 1.1e-40 139.2 14.6 1.3e-40 138.9 10.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Arif-1 PF06770.6 EME26561.1 - 0.79 9.0 5.5 1.4 8.2 3.8 1.4 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Fe-ADH PF00465.14 EME26562.1 - 2.3e-49 167.9 0.0 3.2e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME26562.1 - 2.4e-35 122.0 0.0 2.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EME26562.1 - 2.6e-10 39.6 0.1 4.2e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 3-dehydroquinate synthase ADH_N PF08240.7 EME26563.1 - 1.9e-31 108.0 1.7 1.9e-31 108.0 1.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME26563.1 - 1.5e-29 102.2 0.3 2.1e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME26563.1 - 0.0014 17.7 0.1 0.0025 17.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME26563.1 - 0.0082 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EME26563.1 - 0.087 12.8 0.6 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EME26563.1 - 0.1 11.9 0.8 0.19 11.1 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EME26563.1 - 0.11 12.0 1.3 0.17 11.5 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fe-ADH PF00465.14 EME26564.1 - 2e-55 187.9 0.0 2.7e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME26564.1 - 4.2e-31 108.1 0.1 5.8e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EME26564.1 - 7.7e-06 25.0 1.0 6.4e-05 22.0 0.7 2.1 1 1 0 1 1 1 1 3-dehydroquinate synthase MCD PF05292.6 EME26565.1 - 3.1e-20 72.1 0.0 5.2e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) zf-RING_2 PF13639.1 EME26568.1 - 1.3e-13 50.4 7.5 2.3e-13 49.7 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME26568.1 - 7.7e-10 38.7 2.4 1.5e-09 37.8 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME26568.1 - 2.5e-08 33.7 9.0 4.7e-08 32.9 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME26568.1 - 3.2e-08 33.0 6.9 5.5e-08 32.3 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME26568.1 - 1.2e-06 28.1 7.0 1.9e-06 27.4 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME26568.1 - 1.5e-06 27.7 5.5 2.3e-06 27.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME26568.1 - 0.00027 20.7 1.1 0.00064 19.5 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CamS PF07537.6 EME26568.1 - 0.0053 15.8 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 CamS sex pheromone cAM373 precursor DUF485 PF04341.7 EME26568.1 - 0.064 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 zf-RING_UBOX PF13445.1 EME26568.1 - 0.091 12.4 6.5 0.21 11.3 4.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EME26568.1 - 0.32 10.6 5.2 0.58 9.7 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EME26568.1 - 1 9.2 7.0 4.3 7.2 4.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EME26568.1 - 2.8 8.0 10.3 6.1 6.9 7.1 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME26568.1 - 3.6 7.6 6.3 14 5.7 4.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Kinesin PF00225.18 EME26569.1 - 6.3e-99 330.8 0.7 1.4e-98 329.7 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain SAM_2 PF07647.12 EME26569.1 - 0.026 14.3 0.1 0.068 13.0 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Peptidase_M41 PF01434.13 EME26570.1 - 1.3e-70 237.1 0.3 2.4e-70 236.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME26570.1 - 4.1e-40 137.0 0.0 8.7e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EME26570.1 - 5.7e-13 48.9 3.0 7.8e-11 42.1 0.3 4.0 3 1 0 3 3 3 1 FtsH Extracellular AAA_25 PF13481.1 EME26570.1 - 0.0016 17.9 1.2 0.0076 15.6 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EME26570.1 - 0.0028 17.7 0.0 0.1 12.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME26570.1 - 0.0037 16.9 0.1 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EME26570.1 - 0.0043 16.1 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME26570.1 - 0.005 17.6 0.3 0.048 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EME26570.1 - 0.0085 16.0 0.3 0.076 12.9 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EME26570.1 - 0.011 15.4 0.8 0.037 13.7 0.5 1.9 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EME26570.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME26570.1 - 0.017 14.2 0.1 0.14 11.2 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EME26570.1 - 0.023 13.4 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_2 PF07724.9 EME26570.1 - 0.028 14.3 0.0 0.18 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EME26570.1 - 0.061 13.6 3.1 1.8 8.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EME26570.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME26570.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.18 EME26571.1 - 2.6e-35 119.6 0.6 1e-34 117.7 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EME26571.1 - 2.1e-20 72.1 0.4 3.2e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_C PF00034.16 EME26571.1 - 3.3e-10 40.6 0.0 6.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EME26571.1 - 3.3e-07 30.3 0.4 1.4e-06 28.3 0.2 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Ubiquitin_2 PF14560.1 EME26571.1 - 4.2e-06 26.9 0.1 1.3e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME26571.1 - 0.00033 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Cytochrom_C550 PF14495.1 EME26571.1 - 0.0038 16.6 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Rad60-SLD_2 PF13881.1 EME26571.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME26571.1 - 0.043 14.0 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EME26571.1 - 0.074 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EME26571.1 - 0.08 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Haem_bd PF14376.1 EME26571.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain Abhydrolase_5 PF12695.2 EME26572.1 - 4.2e-16 59.0 0.0 6.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME26572.1 - 6.3e-10 39.3 0.0 5.1e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME26572.1 - 8.6e-09 35.2 0.1 0.00047 19.7 0.0 2.6 2 1 1 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.7 EME26572.1 - 0.00046 18.7 0.1 0.072 11.5 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME26572.1 - 0.0018 17.7 0.0 0.58 9.5 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EME26572.1 - 0.004 16.4 0.0 0.0091 15.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EME26572.1 - 0.0096 15.3 0.1 0.045 13.1 0.0 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.4 EME26572.1 - 0.016 13.7 0.1 0.023 13.1 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DLH PF01738.13 EME26572.1 - 0.066 12.4 0.0 0.39 9.9 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 EME26572.1 - 0.073 12.6 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Pyr_redox_2 PF07992.9 EME26573.1 - 7e-36 123.9 0.0 2.9e-35 121.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME26573.1 - 1.1e-30 105.8 0.1 2.4e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EME26573.1 - 6.3e-15 55.3 0.6 1.3e-12 47.9 0.0 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME26573.1 - 8.2e-10 39.0 0.1 1.2e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME26573.1 - 9.9e-08 31.2 2.3 2.9e-07 29.6 0.5 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EME26573.1 - 3.6e-05 23.0 1.7 0.00032 19.8 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EME26573.1 - 0.00013 21.6 2.2 0.24 11.0 1.2 3.2 3 1 1 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EME26573.1 - 0.00017 20.6 0.1 0.0046 15.9 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EME26573.1 - 0.00021 20.3 11.5 0.0012 17.8 2.5 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME26573.1 - 0.00088 19.0 1.3 0.019 14.7 0.2 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME26573.1 - 0.0016 17.5 0.2 0.0044 16.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 EME26573.1 - 0.0018 17.6 0.0 0.0061 15.9 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 EME26573.1 - 0.0058 15.5 9.7 0.1 11.4 2.6 3.1 3 1 0 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.1 EME26573.1 - 0.0067 16.4 3.2 0.041 13.9 1.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EME26573.1 - 0.056 12.4 1.2 5 6.0 0.5 2.5 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 EME26573.1 - 0.063 12.8 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EME26573.1 - 0.23 9.8 5.0 0.89 7.9 1.4 2.8 3 0 0 3 3 3 0 HI0933-like protein D123 PF07065.9 EME26574.1 - 7.1e-39 133.6 0.1 8.8e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 D123 Glucan_synthase PF02364.10 EME26574.1 - 0.032 12.1 0.0 0.04 11.7 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Mg_trans_NIPA PF05653.9 EME26575.1 - 1.1e-19 70.4 7.9 5.9e-18 64.8 5.5 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EME26575.1 - 0.00036 20.5 3.3 0.00036 20.5 2.3 4.4 3 1 0 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EME26575.1 - 0.0026 17.9 2.7 0.0026 17.9 1.9 3.7 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EME26575.1 - 0.051 13.3 5.0 2.7 7.8 0.1 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 Myb_DNA-binding PF00249.26 EME26576.1 - 7.4e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME26576.1 - 0.0037 17.3 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EME26576.1 - 0.0096 15.7 0.1 0.039 13.8 0.1 2.0 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LrgB PF04172.11 EME26577.1 - 6.8e-38 129.9 14.1 6.8e-38 129.9 9.8 2.7 2 2 0 2 2 2 1 LrgB-like family LrgA PF03788.9 EME26577.1 - 0.0028 17.3 6.4 0.0028 17.3 4.5 3.3 3 1 0 3 3 3 1 LrgA family RRM_1 PF00076.17 EME26578.1 - 8.5e-17 60.5 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EME26578.1 - 9.8e-14 51.4 8.7 9.8e-14 51.4 6.0 2.4 2 1 1 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 EME26578.1 - 3.6e-12 46.0 0.0 7.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26578.1 - 2e-08 33.9 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 EME26579.1 - 2e-07 31.0 1.3 8e-07 29.1 0.9 2.1 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EME26579.1 - 1.3e-06 27.9 1.8 2.1e-06 27.2 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EME26579.1 - 0.00051 20.1 0.4 0.00051 20.1 0.3 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Hus1 PF04005.7 EME26582.1 - 1.4e-36 126.0 4.0 2.3e-36 125.2 2.8 1.3 1 1 0 1 1 1 1 Hus1-like protein NIF PF03031.13 EME26583.1 - 2.4e-18 66.3 1.6 3.5e-18 65.7 1.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_1 PF00515.23 EME26584.1 - 0.0055 16.2 1.5 3.2 7.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Erf4 PF10256.4 EME26584.1 - 0.026 14.3 0.3 0.16 11.8 0.2 2.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family CBFD_NFYB_HMF PF00808.18 EME26585.1 - 4e-12 45.9 0.0 7.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME26585.1 - 9.6e-05 22.0 0.1 0.0014 18.2 0.0 2.1 1 1 1 2 2 2 1 Bromodomain associated Histone PF00125.19 EME26585.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF724 PF05266.9 EME26585.1 - 0.063 12.8 0.7 0.079 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) H2TH PF06831.9 EME26585.1 - 0.13 11.9 0.0 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain UDPG_MGDP_dh_N PF03721.9 EME26586.1 - 2.9e-55 186.5 0.1 4.4e-55 185.9 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EME26586.1 - 3.1e-36 123.7 0.0 6.5e-34 116.2 0.0 2.5 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EME26586.1 - 1.4e-28 98.9 0.0 2.9e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.13 EME26586.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EME26586.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4HBT PF03061.17 EME26588.1 - 4.5e-05 23.4 0.4 0.067 13.3 0.1 2.9 3 1 0 3 3 3 2 Thioesterase superfamily Amidase PF01425.16 EME26589.1 - 3.2e-139 464.6 0.0 3.7e-139 464.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Arm PF00514.18 EME26590.1 - 0.019 14.7 0.8 0.12 12.2 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PAP2 PF01569.16 EME26591.1 - 2.2e-24 85.5 3.2 2.4e-24 85.4 1.6 1.5 1 1 0 1 1 1 1 PAP2 superfamily RDD PF06271.7 EME26591.1 - 0.083 12.7 2.9 1.2 9.0 0.9 2.4 1 1 1 2 2 2 0 RDD family Fe_bilin_red PF05996.7 EME26592.1 - 3.2e-76 255.7 0.0 4e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Eco57I PF07669.6 EME26592.1 - 0.01 16.1 0.1 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Eco57I restriction-modification methylase Peptidase_C12 PF01088.16 EME26593.1 - 2e-61 206.9 0.4 2.2e-61 206.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAM_decarbox PF01536.11 EME26593.1 - 0.00043 19.0 0.3 0.00056 18.6 0.2 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase OmpH PF03938.9 EME26594.1 - 0.13 12.2 24.5 0.19 11.6 17.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PMBR PF09373.5 EME26597.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein-binding repeat SPX PF03105.14 EME26598.1 - 3e-20 73.1 5.5 3.8e-20 72.8 3.8 1.1 1 0 0 1 1 1 1 SPX domain GCD14 PF08704.5 EME26599.1 - 6.7e-54 182.9 0.0 8.5e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EME26599.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26599.1 - 1.1e-08 35.5 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME26599.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EME26599.1 - 0.0046 16.0 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EME26599.1 - 0.0048 16.9 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26599.1 - 0.0081 16.6 0.0 0.022 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26599.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EME26599.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EME26599.1 - 0.12 13.1 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.8 EME26599.1 - 0.17 11.0 0.0 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 Gcd10p family COG4 PF08318.7 EME26600.1 - 2.2e-31 108.8 9.7 4.3e-24 84.8 2.1 3.0 1 1 2 3 3 3 2 COG4 transport protein Dynactin_p22 PF07426.6 EME26600.1 - 0.0032 16.7 1.5 2.2 7.5 0.0 2.8 2 1 0 2 2 2 2 Dynactin subunit p22 NEP PF10167.4 EME26600.1 - 0.048 13.3 1.3 2.9 7.6 0.1 3.4 2 1 1 3 3 3 0 Uncharacterised conserved protein HR1 PF02185.11 EME26600.1 - 0.36 10.5 6.7 3.6 7.3 0.7 3.6 3 0 0 3 3 3 0 Hr1 repeat DUF948 PF06103.6 EME26600.1 - 6.7 6.6 6.7 4.7 7.1 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_L16 PF00252.13 EME26601.1 - 1.3e-30 105.9 0.1 1.5e-30 105.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L15e PF00827.12 EME26602.1 - 6.8e-98 325.8 10.3 7.7e-98 325.6 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L15e PF00827.12 EME26603.1 - 6.8e-98 325.8 10.3 7.7e-98 325.6 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF427 PF04248.7 EME26604.1 - 6.3e-30 102.6 0.1 1.9e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF427) DUF2407 PF10302.4 EME26604.1 - 0.11 12.7 0.1 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain MOR2-PAG1_N PF14222.1 EME26605.1 - 2.1e-15 56.4 10.9 5.7e-15 55.0 7.5 1.7 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Sen15 PF09631.5 EME26605.1 - 4e-07 30.1 0.5 3.6e-06 27.1 0.0 3.0 3 0 0 3 3 3 1 Sen15 protein Fcf2 PF08698.6 EME26606.1 - 5.7e-19 67.9 0.9 1.2e-18 66.9 0.2 1.9 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_L7Ae PF01248.21 EME26607.1 - 4.5e-26 90.1 1.4 5.4e-26 89.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1024 PF06260.7 EME26607.1 - 0.053 13.6 0.1 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) PP2C PF00481.16 EME26608.1 - 8.2e-05 22.1 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C TSCPD PF12637.2 EME26608.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TSCPD domain PP2C PF00481.16 EME26609.1 - 9.9e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C TSCPD PF12637.2 EME26609.1 - 0.0084 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TSCPD domain SSrecog PF03531.9 EME26610.1 - 2e-63 213.6 0.0 3.1e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EME26610.1 - 5.3e-22 77.6 0.1 1.4e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Fe_hyd_lg_C PF02906.9 EME26610.1 - 0.0099 15.1 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Pex14_N PF04695.8 EME26610.1 - 0.39 10.7 3.3 0.77 9.8 2.3 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPP4R2 PF09184.6 EME26610.1 - 0.46 9.9 18.8 0.63 9.5 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 EME26610.1 - 0.57 9.3 15.5 0.76 8.9 10.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 EME26610.1 - 8.2 5.7 19.3 12 5.1 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) p450 PF00067.17 EME26611.1 - 6.9e-54 183.0 0.1 1.2e-46 159.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EME26612.1 - 2.4e-55 187.9 0.2 4.3e-48 164.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2-oxoacid_dh PF00198.18 EME26613.1 - 2.3e-70 236.4 0.3 3.4e-70 235.9 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME26613.1 - 8.2e-20 70.2 0.4 2.4e-19 68.7 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EME26613.1 - 1.5e-07 30.9 0.0 3.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 EME26613.1 - 0.018 15.2 0.2 0.09 13.0 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.1 EME26613.1 - 0.034 13.8 0.5 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like 2-oxoacid_dh PF00198.18 EME26614.1 - 2.3e-70 236.4 0.3 3.4e-70 235.9 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME26614.1 - 8.2e-20 70.2 0.4 2.4e-19 68.7 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EME26614.1 - 1.5e-07 30.9 0.0 3.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 EME26614.1 - 0.018 15.2 0.2 0.09 13.0 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.1 EME26614.1 - 0.034 13.8 0.5 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like Got1 PF04178.7 EME26615.1 - 3.6e-14 52.8 11.6 4.1e-14 52.7 8.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family dsrm PF00035.20 EME26616.1 - 7e-08 32.9 0.0 2.1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Pox_MCEL PF03291.11 EME26617.1 - 3e-31 108.5 0.1 6.6e-31 107.3 0.1 1.5 1 1 0 1 1 1 1 mRNA capping enzyme SAPS PF04499.10 EME26618.1 - 7.4e-11 41.3 2.4 4.9e-10 38.6 0.0 2.7 3 1 0 4 4 4 1 SIT4 phosphatase-associated protein F-box-like PF12937.2 EME26619.1 - 2.2e-14 52.9 0.7 6.5e-14 51.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME26619.1 - 4.2e-12 45.3 0.7 1e-11 44.1 0.5 1.7 1 0 0 1 1 1 1 F-box domain BTB PF00651.26 EME26620.1 - 3e-28 98.0 3.0 4.1e-13 49.2 0.1 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EME26620.1 - 4e-09 36.6 0.0 2.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME26620.1 - 9.6e-09 35.5 0.0 3.9e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EME26620.1 - 1.1e-08 34.4 0.6 6.4e-05 22.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EME26620.1 - 3.6e-08 33.3 0.1 9e-07 28.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME26620.1 - 6.6e-05 22.7 0.0 0.025 14.8 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Thioredoxin PF00085.15 EME26621.1 - 6.6e-23 80.3 0.0 8.5e-23 80.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME26621.1 - 1.5e-06 28.4 0.0 2e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME26621.1 - 1.3e-05 25.2 0.0 0.0084 16.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EME26621.1 - 0.00015 21.6 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EME26621.1 - 0.00025 20.6 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 EME26621.1 - 0.0038 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.1 EME26621.1 - 0.0058 16.4 0.1 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 EME26621.1 - 0.0086 15.6 0.0 0.76 9.3 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin HyaE PF07449.6 EME26621.1 - 0.012 15.5 0.0 0.033 14.0 0.0 1.7 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 EME26621.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family DUF836 PF05768.9 EME26621.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EME26621.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EME26621.1 - 0.057 12.9 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 EME26621.1 - 0.064 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DXPR_C PF13288.1 EME26622.1 - 3.1e-45 153.1 0.0 6e-45 152.1 0.0 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.11 EME26622.1 - 8.3e-41 139.5 0.0 1.6e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.7 EME26622.1 - 1.9e-38 130.2 0.1 8.5e-38 128.1 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Glyco_tran_WecB PF03808.8 EME26622.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Nbl1_Borealin_N PF10444.4 EME26623.1 - 2.3e-07 30.0 0.4 5.5e-07 28.8 0.3 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF668 PF05003.7 EME26623.1 - 0.022 14.9 3.3 2 8.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF668) DUF763 PF05559.6 EME26623.1 - 6.4 5.6 10.9 3.2 6.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Arf PF00025.16 EME26624.1 - 1.1e-78 262.5 0.0 1.2e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME26624.1 - 2.3e-14 53.0 0.0 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME26624.1 - 2.3e-14 53.0 0.0 2.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME26624.1 - 4.8e-12 45.2 1.4 6.9e-09 34.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME26624.1 - 1.9e-11 43.5 0.0 2.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME26624.1 - 8.7e-10 39.1 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME26624.1 - 6.9e-06 26.0 0.0 1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EME26624.1 - 0.0038 16.3 0.1 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EME26624.1 - 0.0044 16.4 0.0 0.035 13.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EME26624.1 - 0.063 13.1 0.1 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EME26624.1 - 0.16 11.6 0.5 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain IPK PF03770.11 EME26625.1 - 1.6e-56 191.0 0.9 3.4e-56 190.0 0.7 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_L6e PF01159.14 EME26626.1 - 6.6e-30 103.5 0.1 6.6e-30 103.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e Ehbp PF10622.4 EME26626.1 - 0.067 13.1 0.1 0.84 9.6 0.1 2.2 1 1 1 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) Complex1_30kDa PF00329.14 EME26627.1 - 4.8e-30 103.8 0.0 8.1e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PRA1 PF03208.14 EME26628.1 - 5.1e-28 97.3 5.4 7.4e-28 96.8 3.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2516 PF10724.4 EME26628.1 - 1.9 8.5 6.4 20 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF4131 PF13567.1 EME26628.1 - 2.1 7.7 7.0 4.1 6.7 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3040 PF11239.3 EME26628.1 - 8.2 6.5 7.0 2.2 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Glycos_transf_1 PF00534.15 EME26629.1 - 9.7e-32 109.7 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME26629.1 - 8.6e-10 38.8 0.0 2.4e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME26629.1 - 2.6e-08 34.1 0.0 4.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EME26629.1 - 3.6e-07 30.0 0.0 1.9e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EME26629.1 - 0.0045 17.2 0.2 0.05 13.8 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferases group 1 WD40 PF00400.27 EME26630.1 - 6.8e-16 57.4 21.7 5e-06 26.1 0.1 6.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME26630.1 - 0.042 12.5 2.1 0.7 8.5 0.4 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Chloroa_b-bind PF00504.16 EME26631.1 - 6.3e-45 153.2 0.0 7.8e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CS PF04969.11 EME26632.1 - 3e-12 46.8 0.0 5.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Ribonuc_red_sm PF00268.16 EME26633.1 - 1.7e-113 378.3 1.0 2e-113 378.0 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.14 EME26633.1 - 0.011 15.3 0.1 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Complex1_LYR PF05347.10 EME26634.1 - 1.4e-09 37.6 1.5 2.1e-09 37.0 1.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME26634.1 - 1.8e-07 31.2 2.4 2.5e-07 30.8 1.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME26635.1 - 2.8e-07 30.2 0.1 3.7e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME26635.1 - 1.5e-05 25.1 0.2 1.6e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like MRP-L27 PF09809.4 EME26636.1 - 1.8e-14 53.3 0.1 2.2e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF1161 PF06649.7 EME26637.1 - 0.17 11.8 0.2 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) PDDEXK_1 PF12705.2 EME26638.1 - 1.7e-10 40.6 0.0 6.7e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EME26638.1 - 0.047 13.6 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF83 WD40 PF00400.27 EME26639.1 - 0.00087 19.0 12.9 0.016 15.0 0.8 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Ebp2 PF05890.7 EME26640.1 - 6e-34 117.5 19.1 7.5e-34 117.2 13.2 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Exonuc_VII_L PF02601.10 EME26640.1 - 1 8.5 9.6 1.7 7.7 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EME26640.1 - 1.6 8.6 14.1 2.3 8.1 9.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ebp2 PF05890.7 EME26641.1 - 6e-34 117.5 19.1 7.5e-34 117.2 13.2 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Exonuc_VII_L PF02601.10 EME26641.1 - 1 8.5 9.6 1.7 7.7 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EME26641.1 - 1.6 8.6 14.1 2.3 8.1 9.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GCV_T PF01571.16 EME26642.1 - 1e-68 230.8 0.0 1.3e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME26642.1 - 9e-24 83.3 0.1 1.7e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EME26642.1 - 0.00031 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 EME26642.1 - 0.039 13.9 0.0 6.7 6.7 0.0 2.6 1 1 1 2 2 2 0 GTP-binding protein TrmE N-terminus Syja_N PF02383.13 EME26643.1 - 2.2e-71 240.2 0.0 3.4e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Romo1 PF10247.4 EME26644.1 - 1e-15 57.6 10.0 1.4e-15 57.2 6.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EME26644.1 - 0.46 10.5 5.2 0.68 9.9 3.6 1.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Transgly_assoc PF04226.8 EME26644.1 - 3.2 7.9 6.8 12 6.1 4.7 2.0 1 1 0 1 1 1 0 Transglycosylase associated protein TatC PF00902.13 EME26645.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Sugar_tr PF00083.19 EME26646.1 - 1.1e-82 278.0 25.7 1.3e-82 277.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME26646.1 - 6.3e-30 104.0 54.4 1.1e-27 96.6 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MCD PF05292.6 EME26647.1 - 4.7e-19 68.2 0.0 8.1e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) AATF-Che1 PF13339.1 EME26647.1 - 0.079 13.1 2.3 0.14 12.2 1.6 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Tim17 PF02466.14 EME26648.1 - 8.1e-17 61.4 6.7 1.1e-16 61.1 4.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_12 PF08242.7 EME26649.1 - 5.1e-09 36.5 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26649.1 - 1.7e-08 34.3 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26649.1 - 9.6e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26649.1 - 0.0003 21.3 0.0 0.00047 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26649.1 - 0.0024 17.4 0.1 0.004 16.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26649.1 - 0.0025 18.2 0.1 0.0053 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME26650.1 - 2.7e-07 31.0 0.0 1.1e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26650.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26650.1 - 0.0078 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26650.1 - 0.015 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME26650.1 - 0.029 14.7 0.0 0.22 11.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain FKBP_C PF00254.23 EME26651.1 - 2.8e-49 165.0 3.7 3.3e-32 110.3 0.1 3.5 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EME26651.1 - 2e-10 40.1 11.5 2.7e-06 26.9 0.9 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EME26651.1 - 2.5e-09 36.3 6.5 0.00013 21.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME26651.1 - 2.2e-08 33.3 2.8 0.0014 18.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME26651.1 - 0.00025 21.6 0.1 0.1 13.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME26651.1 - 0.0032 17.5 0.1 0.27 11.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME26651.1 - 0.015 15.2 0.5 0.68 9.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME26651.1 - 0.13 12.9 0.1 0.67 10.7 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME26651.1 - 0.47 10.3 7.3 1.2 9.0 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF824 PF05688.6 EME26651.1 - 2.1 8.0 5.7 19 4.9 0.7 2.9 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) TFIIS_M PF07500.9 EME26652.1 - 4.8e-32 110.4 3.1 7.6e-32 109.7 2.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EME26652.1 - 3e-19 68.3 8.2 5.9e-19 67.4 5.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Borrelia_REV PF03978.8 EME26652.1 - 9.7e-05 22.1 1.0 0.00014 21.6 0.7 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein Elf1 PF05129.8 EME26652.1 - 0.017 14.8 5.3 0.017 14.8 3.7 2.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like AAA-ATPase_like PF09820.4 EME26652.1 - 0.02 14.0 0.4 0.031 13.4 0.3 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase DUF2096 PF09869.4 EME26652.1 - 0.043 13.6 0.2 0.072 12.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) DNA_RNApol_7kD PF03604.8 EME26652.1 - 0.052 13.0 2.1 6.3 6.3 0.0 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ABC1 PF03109.11 EME26652.1 - 0.13 12.2 0.4 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 ABC1 family Baculo_LEF5_C PF11792.3 EME26652.1 - 0.54 9.6 3.4 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 EME26652.1 - 1.3 8.8 7.0 16 5.4 4.8 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EME26652.1 - 3.1 7.8 6.7 18 5.3 4.6 2.3 1 1 0 1 1 1 0 Zinc ribbon domain FH2 PF02181.18 EME26653.1 - 2e-57 194.8 1.2 2e-57 194.8 0.9 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain PH PF00169.24 EME26653.1 - 1.3e-06 28.5 9.4 0.00098 19.2 1.3 2.7 2 0 0 2 2 2 2 PH domain Glutaredoxin PF00462.19 EME26653.1 - 0.0012 18.7 0.0 0.0043 17.0 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin IQ PF00612.22 EME26653.1 - 0.0045 16.5 1.3 0.017 14.6 0.9 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif WHG PF13305.1 EME26653.1 - 0.097 13.2 0.1 3.1 8.4 0.0 3.0 3 0 0 3 3 3 0 WHG domain DUF2358 PF10184.4 EME26654.1 - 8.3e-05 22.4 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) CBFD_NFYB_HMF PF00808.18 EME26656.1 - 2.1e-26 91.7 0.1 2.8e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME26656.1 - 0.0027 17.7 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EME26656.1 - 0.035 14.3 0.0 0.08 13.2 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 EME26656.1 - 0.045 13.4 0.0 0.083 12.6 0.0 1.4 1 1 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.11 EME26656.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Esterase PF00756.15 EME26657.1 - 8.1e-49 166.3 0.0 9.9e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EME26657.1 - 9.4e-07 27.9 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME26657.1 - 0.0002 20.2 0.0 0.039 12.7 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_5 PF12695.2 EME26657.1 - 0.00035 20.3 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME26657.1 - 0.00038 19.0 0.0 0.00052 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EME26657.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EME26657.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EME26657.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family SMC_N PF02463.14 EME26658.1 - 1.6e-62 210.5 3.6 2.5e-62 209.9 2.5 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME26658.1 - 9.3e-23 80.4 0.0 3.2e-22 78.7 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EME26658.1 - 1.4e-21 77.7 10.3 1.4e-21 77.7 7.1 6.9 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 EME26658.1 - 7.1e-14 52.4 5.9 9.4e-08 32.3 1.7 4.2 3 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 EME26658.1 - 5.8e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EME26658.1 - 0.01 15.0 40.4 0.36 9.9 1.4 6.0 2 2 4 6 6 6 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 EME26658.1 - 0.23 10.9 0.0 0.23 10.9 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3584 PF12128.3 EME26658.1 - 6 4.0 115.5 0.95 6.7 37.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.6 EME26659.1 - 0.046 13.0 7.3 0.026 13.8 1.6 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4094 PF13334.1 EME26659.1 - 0.44 10.9 6.8 0.084 13.2 0.8 2.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) DUF2201_N PF13203.1 EME26659.1 - 0.71 8.9 4.1 12 4.9 1.4 2.4 2 1 0 2 2 2 0 Putative metallopeptidase domain ABC_tran_2 PF12848.2 EME26659.1 - 1.2 9.0 11.3 0.5 10.2 4.6 2.4 2 0 0 2 2 2 0 ABC transporter DUF964 PF06133.6 EME26659.1 - 5.4 7.0 12.0 0.82 9.7 3.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF964) CDC37_N PF03234.9 EME26659.1 - 8.1 6.7 13.0 28 4.9 5.8 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding AbiH PF14253.1 EME26659.1 - 9.4 5.7 8.1 5.8 6.4 4.1 1.6 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH GDC-P PF02347.11 EME26660.1 - 5.3e-117 391.1 0.1 6.6e-117 390.7 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Toxin_55 PF15606.1 EME26660.1 - 0.062 13.2 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative toxin 55 CCDC32 PF14989.1 EME26661.1 - 0.099 12.4 1.9 0.1 12.4 1.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 FlaC_arch PF05377.6 EME26661.1 - 0.77 9.6 4.5 2.5 8.0 0.1 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) AMPKBI PF04739.10 EME26662.1 - 1.2e-14 53.9 0.5 2.3e-12 46.6 0.1 2.8 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Snf7 PF03357.16 EME26663.1 - 1.3e-18 66.9 16.4 2.1e-18 66.3 11.4 1.3 1 0 0 1 1 1 1 Snf7 PKI PF02827.11 EME26663.1 - 0.15 12.1 1.6 0.42 10.7 1.1 1.8 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Snapin_Pallidin PF14712.1 EME26663.1 - 7.2 6.9 12.7 2.5 8.4 0.4 3.2 2 2 1 3 3 3 0 Snapin/Pallidin DUF342 PF03961.8 EME26663.1 - 8.2 4.7 13.7 0.56 8.5 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Glyco_tran_28_C PF04101.11 EME26664.1 - 3e-08 33.4 0.0 4.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EME26664.1 - 0.00021 20.5 0.1 0.0029 16.8 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 1 MGDG_synth PF06925.6 EME26664.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase PAF-AH_p_II PF03403.8 EME26665.1 - 4.6e-47 160.1 0.4 2.3e-46 157.7 0.1 2.0 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EME26665.1 - 2.5e-13 50.0 0.0 4.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME26665.1 - 1.3e-09 37.3 0.0 4.3e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME26665.1 - 1.9e-08 33.4 0.0 0.00011 21.0 0.0 2.4 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.2 EME26665.1 - 4.8e-08 33.1 0.0 1.6e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME26665.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME26665.1 - 0.012 15.4 0.0 0.041 13.7 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 EME26665.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.7 EME26665.1 - 0.04 12.4 0.0 0.13 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EME26665.1 - 0.042 13.2 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.8 EME26665.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EME26665.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Spore_III_AB PF09548.5 EME26666.1 - 0.11 12.2 2.3 0.15 11.8 1.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ATP-synt_G PF04718.10 EME26666.1 - 0.13 12.9 0.1 0.22 12.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit OrfB_IS605 PF01385.14 EME26666.1 - 0.15 11.4 1.4 0.2 11.0 1.0 1.1 1 0 0 1 1 1 0 Probable transposase Endotoxin_N PF03945.9 EME26666.1 - 0.25 10.7 1.5 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF947 PF06102.7 EME26667.1 - 6.1e-26 91.2 22.4 9.2e-26 90.6 15.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) GvpL_GvpF PF06386.6 EME26667.1 - 0.45 10.0 4.6 0.87 9.1 3.2 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TFIID_30kDa PF03540.8 EME26670.1 - 1.5e-21 75.9 0.1 2.2e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Flavi_DEAD PF07652.9 EME26670.1 - 0.07 12.8 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain GSHPx PF00255.14 EME26672.1 - 3.2e-28 97.2 1.2 1.5e-26 91.8 0.9 2.3 1 1 0 1 1 1 1 Glutathione peroxidase DUF647 PF04884.9 EME26673.1 - 1.8e-71 240.2 0.2 2.5e-71 239.8 0.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TauE PF01925.14 EME26673.1 - 0.015 14.7 0.3 0.025 14.0 0.2 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF647 PF04884.9 EME26674.1 - 1.8e-71 240.2 0.2 2.5e-71 239.8 0.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TauE PF01925.14 EME26674.1 - 0.015 14.7 0.3 0.025 14.0 0.2 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE 4HBT PF03061.17 EME26675.1 - 1.4e-12 47.5 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME26675.1 - 0.0024 17.6 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EME26675.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Acetyltransf_7 PF13508.1 EME26676.1 - 3.7e-06 27.0 0.0 0.00067 19.7 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME26676.1 - 0.00019 21.3 0.0 0.00033 20.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME26676.1 - 0.00025 21.1 0.0 0.0016 18.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Pyr_redox_dim PF02852.17 EME26676.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain CLASP_N PF12348.3 EME26677.1 - 3.1e-05 23.4 2.4 0.074 12.4 0.0 2.9 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EME26677.1 - 3.8e-05 23.3 7.2 5.3 7.3 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EME26677.1 - 0.00088 19.5 0.0 0.018 15.2 0.0 2.9 2 2 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EME26677.1 - 0.0014 19.0 0.1 5.4 7.6 0.0 3.8 4 1 1 5 5 5 2 HEAT-like repeat DUF1546 PF07571.8 EME26677.1 - 0.087 12.9 0.0 3.4 7.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1546) TPR_16 PF13432.1 EME26678.1 - 1.3e-22 79.8 2.4 5e-05 23.8 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EME26678.1 - 7.8e-22 75.6 0.0 3.7e-05 23.5 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME26678.1 - 3e-21 74.8 0.9 2.6e-07 30.1 0.0 4.8 3 1 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 EME26678.1 - 2.2e-20 70.8 8.7 0.00074 19.2 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME26678.1 - 2.6e-18 66.1 0.2 2.6e-05 24.4 0.0 4.2 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME26678.1 - 9.2e-18 63.1 11.1 0.00022 21.5 0.0 7.7 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME26678.1 - 9.5e-13 47.8 3.5 0.0005 19.9 0.0 4.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME26678.1 - 5.8e-12 44.6 0.0 0.0034 16.9 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME26678.1 - 4.1e-11 41.8 0.0 0.0059 16.3 0.0 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME26678.1 - 1.9e-08 33.4 2.3 0.065 13.0 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME26678.1 - 1.9e-07 30.4 8.9 6.6e-05 22.1 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME26678.1 - 1.6e-06 28.1 5.1 0.16 12.5 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME26678.1 - 0.00012 21.8 3.5 0.2 11.5 0.3 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EME26678.1 - 0.0017 18.1 2.8 6.4 6.5 0.0 5.0 4 2 1 5 5 5 1 Mad3/BUB1 homology region 1 TPR_20 PF14561.1 EME26678.1 - 0.0033 17.5 0.1 0.069 13.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AbiH PF14253.1 EME26678.1 - 0.63 9.5 5.0 0.3 10.6 1.6 1.8 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH PPR PF01535.15 EME26678.1 - 0.88 9.6 7.3 97 3.2 0.0 5.8 8 0 0 8 8 6 0 PPR repeat TPR_10 PF13374.1 EME26678.1 - 3.7 7.6 10.6 35 4.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat HAT PF02184.11 EME26678.1 - 6.7 6.5 8.9 2.7 7.8 0.0 4.6 5 1 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_4 PF07721.9 EME26678.1 - 7.3 7.3 13.0 28 5.5 0.3 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat ABC1 PF03109.11 EME26679.1 - 9.2e-34 115.9 0.1 4.1e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 EME26679.1 - 1.6e-07 30.7 0.0 5.1e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EME26679.1 - 3.6e-06 26.8 0.4 0.00026 20.8 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EME26679.1 - 0.0009 18.5 0.2 0.0028 16.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EME26679.1 - 0.0056 15.7 0.1 0.021 13.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase CLASP_N PF12348.3 EME26680.1 - 3.7e-17 62.4 5.6 3.7e-17 62.4 3.9 2.0 2 1 0 2 2 2 1 CLASP N terminal DUF208 PF02677.9 EME26680.1 - 0.0041 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized BCR, COG1636 CLASP_N PF12348.3 EME26681.1 - 3.7e-17 62.4 5.6 3.7e-17 62.4 3.9 2.0 2 1 0 2 2 2 1 CLASP N terminal DUF208 PF02677.9 EME26681.1 - 0.0041 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized BCR, COG1636 Acyltransferase PF01553.16 EME26682.1 - 2.3e-16 59.4 0.0 4.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3810 PF12725.2 EME26682.1 - 4.9 5.9 5.8 10 4.9 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DNA_pol3_alpha PF07733.7 EME26683.1 - 3.2e-152 506.8 0.0 5.2e-152 506.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit PHP PF02811.14 EME26683.1 - 4.5e-42 143.7 0.0 1.5e-40 138.8 0.0 2.8 2 1 0 2 2 2 1 PHP domain HHH_6 PF14579.1 EME26683.1 - 2.3e-22 78.8 0.0 6.9e-22 77.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.2 EME26683.1 - 7.9e-05 22.5 0.0 0.0003 20.6 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF655 PF04919.7 EME26683.1 - 0.0081 15.8 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) LETM1 PF07766.8 EME26684.1 - 5.5e-16 58.3 0.1 5.5e-16 58.3 0.1 2.6 3 1 0 3 3 3 1 LETM1-like protein Rieske PF00355.21 EME26685.1 - 4.2e-13 48.6 0.0 6.1e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EME26685.1 - 4.1e-07 29.6 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain adh_short PF00106.20 EME26686.1 - 1.7e-25 89.8 0.0 2.4e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME26686.1 - 9.6e-22 77.9 0.0 1.1e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME26686.1 - 6e-07 29.2 0.0 8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME26686.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME26686.1 - 0.002 16.8 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME26686.1 - 0.0035 17.3 0.0 0.0068 16.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EME26686.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EME26686.1 - 0.026 13.8 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 EME26686.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.7 EME26686.1 - 0.16 10.8 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein PTH2 PF01981.11 EME26687.1 - 3.3e-45 152.5 0.1 4.1e-45 152.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Mito_carr PF00153.22 EME26688.1 - 2e-55 184.4 0.0 2.1e-18 65.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_primase_S PF01896.14 EME26688.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Mito_carr PF00153.22 EME26689.1 - 2e-55 184.4 0.0 2.1e-18 65.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_primase_S PF01896.14 EME26689.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit ACT PF01842.20 EME26690.1 - 1.3e-08 34.1 0.6 0.00034 20.0 0.0 3.7 4 0 0 4 4 4 2 ACT domain ACT_4 PF13291.1 EME26690.1 - 1.6e-08 34.7 0.1 0.028 14.7 0.0 4.1 4 1 0 4 4 4 2 ACT domain DnaJ-X PF14308.1 EME26690.1 - 0.075 12.3 0.1 0.16 11.1 0.1 1.5 1 0 0 1 1 1 0 X-domain of DnaJ-containing Cullin PF00888.17 EME26691.1 - 3.2e-156 521.3 24.8 4.4e-156 520.8 17.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME26691.1 - 2.2e-27 94.6 0.7 6.2e-27 93.2 0.5 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain TrmB PF01978.14 EME26691.1 - 0.0059 16.2 1.6 1.9 8.2 0.0 2.9 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB Clp1 PF06807.9 EME26692.1 - 3.4e-34 118.3 0.0 4.9e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EME26692.1 - 7.6e-09 35.4 0.0 5.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EME26692.1 - 0.00086 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME26692.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME26692.1 - 0.053 13.4 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME26692.1 - 0.1 12.9 0.1 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EME26692.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EME26692.1 - 0.13 12.7 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EME26692.1 - 0.14 12.1 0.2 0.5 10.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain ATP-synt_G PF04718.10 EME26693.1 - 0.0088 16.6 0.1 0.013 16.1 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF4279 PF14106.1 EME26693.1 - 0.07 13.0 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) RRM_1 PF00076.17 EME26694.1 - 1.1e-14 53.8 0.0 1.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME26694.1 - 8.5e-11 41.5 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26694.1 - 3.3e-10 39.8 0.0 4.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IBN_N PF03810.14 EME26695.1 - 1.4e-13 50.5 3.1 3.6e-13 49.2 0.5 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain IBN_N PF03810.14 EME26696.1 - 1.4e-13 50.5 3.1 3.6e-13 49.2 0.5 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Rhomboid PF01694.17 EME26697.1 - 3.5e-31 108.1 15.8 1.1e-30 106.6 8.8 2.2 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.10 EME26697.1 - 0.00011 21.7 2.7 0.00022 20.7 1.7 1.6 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 EME26697.1 - 0.12 12.7 1.4 0.37 11.1 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) GDPD PF03009.12 EME26698.1 - 1e-37 130.0 0.0 1.5e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 EME26699.1 - 1e-37 130.0 0.0 1.5e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GrpE PF01025.14 EME26702.1 - 4.9e-42 143.2 9.2 4.9e-42 143.2 6.4 1.6 2 1 0 2 2 2 1 GrpE ARL2_Bind_BART PF11527.3 EME26702.1 - 0.16 11.8 5.2 0.57 9.9 0.0 2.7 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART APG6 PF04111.7 EME26702.1 - 3.9 6.4 11.9 3.6 6.5 7.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 zf-RING_2 PF13639.1 EME26703.1 - 9.4e-12 44.5 7.6 9.4e-12 44.5 5.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME26703.1 - 1.5e-05 24.9 9.0 3.3e-05 23.8 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME26703.1 - 2.6e-05 24.2 8.3 7.8e-05 22.7 5.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME26703.1 - 0.0014 18.2 9.2 0.0033 17.0 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME26703.1 - 0.0019 17.8 6.7 0.0039 16.8 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME26703.1 - 0.002 17.7 4.6 0.0038 16.8 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME26703.1 - 0.048 13.5 0.7 0.1 12.4 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EME26703.1 - 0.05 13.1 3.8 0.1 12.1 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EME26703.1 - 0.52 10.0 4.6 1.2 8.8 3.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Isochorismatase PF00857.15 EME26705.1 - 1e-33 116.7 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Utp14 PF04615.8 EME26707.1 - 5.9e-87 292.5 75.4 4.9e-45 153.9 35.8 2.1 1 1 1 2 2 2 2 Utp14 protein Ribosomal_L32p PF01783.18 EME26708.1 - 0.0017 18.5 4.0 0.0024 17.9 2.7 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family C1_1 PF00130.17 EME26708.1 - 0.093 12.4 0.7 0.13 11.9 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MutS_V PF00488.16 EME26709.1 - 1.1e-51 175.5 0.3 9.1e-51 172.5 0.2 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME26709.1 - 1.7e-22 80.2 4.7 1.7e-22 80.2 3.2 3.5 2 2 0 2 2 2 1 MutS domain III DUF1771 PF08590.5 EME26709.1 - 1.2e-12 47.6 10.8 1.4e-12 47.4 6.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EME26709.1 - 7.3e-11 42.1 0.1 1.8e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Smr domain MutS_II PF05188.12 EME26709.1 - 3.8e-10 39.9 0.1 1.3e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME26709.1 - 5e-05 23.4 0.1 5e-05 23.4 0.1 3.1 2 1 1 3 3 3 1 MutS family domain IV CUE PF02845.11 EME26709.1 - 0.0042 16.5 0.1 0.31 10.5 0.0 2.9 2 0 0 2 2 2 1 CUE domain AAA_29 PF13555.1 EME26709.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DNA_pol_alpha_N PF12254.3 EME26709.1 - 0.087 12.6 1.5 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal MutS_V PF00488.16 EME26710.1 - 9.8e-52 175.6 0.3 8.4e-51 172.6 0.2 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME26710.1 - 2.2e-22 79.8 5.2 2.2e-22 79.8 3.6 3.5 2 2 0 2 2 2 1 MutS domain III DUF1771 PF08590.5 EME26710.1 - 1.1e-12 47.7 10.8 1.3e-12 47.5 6.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) MutS_II PF05188.12 EME26710.1 - 3.5e-10 40.0 0.1 1.2e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME26710.1 - 4.7e-05 23.4 0.1 4.7e-05 23.4 0.1 3.0 2 1 1 3 3 3 1 MutS family domain IV CUE PF02845.11 EME26710.1 - 0.0037 16.7 0.1 0.29 10.6 0.0 2.9 2 0 0 2 2 2 1 CUE domain AAA_29 PF13555.1 EME26710.1 - 0.023 14.2 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DNA_pol_alpha_N PF12254.3 EME26710.1 - 0.091 12.5 1.5 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Cwf_Cwc_15 PF04889.7 EME26711.1 - 2e-36 125.9 33.3 4.8e-25 88.6 0.8 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EME26711.1 - 0.02 14.2 28.6 0.027 13.7 19.8 1.2 1 0 0 1 1 1 0 SDA1 CAF-1_p150 PF11600.3 EME26711.1 - 1.1 8.6 34.7 1.5 8.1 24.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EME26711.1 - 1.9 8.2 23.9 2.3 7.9 16.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop53 PF07767.6 EME26711.1 - 3.2 6.6 30.6 4.1 6.2 21.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 EME26711.1 - 9.3 4.0 33.6 12 3.7 23.3 1.0 1 0 0 1 1 1 0 Nop14-like family GRIM-19 PF06212.7 EME26712.1 - 1.4e-36 125.1 0.0 1.7e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF2681 PF10883.3 EME26712.1 - 0.091 12.9 0.3 0.17 12.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) MAD PF05557.8 EME26713.1 - 1.2e-17 63.2 10.9 1.2e-17 63.2 7.5 3.2 1 1 1 2 2 2 1 Mitotic checkpoint protein Tropomyosin_1 PF12718.2 EME26713.1 - 0.0069 16.2 17.3 0.0069 16.2 12.0 7.1 2 1 2 7 7 7 1 Tropomyosin like Peripla_BP_2 PF01497.13 EME26713.1 - 0.026 13.6 0.3 0.026 13.6 0.2 2.4 2 0 0 2 2 2 0 Periplasmic binding protein A_deaminase PF00962.17 EME26715.1 - 6.5e-98 327.6 0.0 1e-97 327.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Grp1_Fun34_YaaH PF01184.14 EME26716.1 - 1.2e-25 90.0 20.0 1.7e-25 89.5 13.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF308 PF03729.8 EME26716.1 - 0.028 14.4 5.3 0.028 14.4 3.6 2.8 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Abhydrolase_1 PF00561.15 EME26717.1 - 4.8e-09 36.1 0.0 8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME26717.1 - 0.00035 20.5 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Brr6_like_C_C PF10104.4 EME26718.1 - 9.3e-39 132.0 1.8 1.5e-38 131.3 1.2 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RSN1_TM PF13967.1 EME26718.1 - 0.089 12.3 0.2 7.6 6.0 0.0 2.7 2 1 0 2 2 2 0 Late exocytosis, associated with Golgi transport OAD_gamma PF04277.8 EME26718.1 - 1.2 9.5 7.7 8.7 6.8 0.3 3.2 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_S21e PF01249.13 EME26721.1 - 3e-36 123.2 0.1 3.3e-36 123.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAIM1 PF06905.8 EME26721.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) DUF4337 PF14235.1 EME26722.1 - 0.029 14.2 1.2 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) O-FucT PF10250.4 EME26723.1 - 7.3e-15 54.9 1.4 2.3e-10 40.1 0.4 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase TPR_11 PF13414.1 EME26724.1 - 1.9e-21 75.4 24.8 2.6e-06 26.9 0.0 7.9 6 2 2 9 9 9 4 TPR repeat TPR_2 PF07719.12 EME26724.1 - 3.5e-20 70.2 25.5 0.00025 20.7 0.0 11.6 13 0 0 13 13 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME26724.1 - 6.4e-20 71.2 10.2 0.00012 22.6 0.0 7.3 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME26724.1 - 1.8e-19 68.4 27.4 0.0026 18.2 0.0 11.8 8 4 6 14 14 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME26724.1 - 3.6e-19 68.8 18.2 2e-05 24.8 0.0 8.0 5 3 4 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME26724.1 - 8.7e-16 57.6 23.9 0.00056 19.7 0.3 7.5 2 1 7 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME26724.1 - 1.8e-13 49.4 14.5 0.00043 19.7 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME26724.1 - 7.8e-13 47.1 14.8 0.024 14.4 0.1 8.9 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME26724.1 - 1.2e-11 43.4 17.6 1.3 8.9 0.1 10.6 10 1 1 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 EME26724.1 - 1.2e-10 41.3 27.1 6.6e-05 22.9 0.3 8.1 4 2 7 11 11 10 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EME26724.1 - 2.4e-09 37.0 12.0 0.5 10.9 0.0 9.4 11 0 0 11 11 9 3 Tetratricopeptide repeat NARP1 PF12569.3 EME26724.1 - 1.9e-07 30.2 3.5 0.13 10.9 0.0 4.6 4 1 2 6 6 6 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 EME26724.1 - 2.3e-07 30.4 4.6 15 5.7 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat PPR PF01535.15 EME26724.1 - 4e-06 26.4 2.5 3.3 7.9 0.0 6.0 7 0 0 7 7 6 1 PPR repeat TPR_15 PF13429.1 EME26724.1 - 6.1e-06 25.4 11.2 0.00039 19.5 6.7 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME26724.1 - 7.8e-06 25.7 9.9 0.86 9.9 0.0 7.2 9 1 0 9 9 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME26724.1 - 0.00016 21.4 16.7 0.049 13.4 0.1 6.6 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EME26724.1 - 0.00017 21.6 2.0 45 4.8 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 EME26724.1 - 0.00019 20.3 2.3 0.11 11.2 0.1 2.9 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 EME26724.1 - 0.00024 21.1 0.5 13 6.3 0.0 5.9 6 0 0 6 6 6 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME26724.1 - 0.00095 18.5 5.1 2.8 7.5 0.0 4.9 5 0 0 5 5 5 1 PPR repeat SNAP PF14938.1 EME26724.1 - 0.0059 15.7 4.3 0.64 9.1 0.3 3.7 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 EME26724.1 - 0.0072 16.4 8.8 8.4 6.5 0.0 6.6 6 3 2 8 8 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EME26724.1 - 0.16 12.1 4.6 6.6 6.9 0.0 4.0 4 1 1 5 5 4 0 Alkyl sulfatase dimerisation PPR_2 PF13041.1 EME26724.1 - 0.19 11.7 1.3 39 4.3 0.1 4.4 6 0 0 6 6 5 0 PPR repeat family Peptidase_M14 PF00246.19 EME26725.1 - 2.1e-21 76.7 0.0 4.9e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase UDG PF03167.14 EME26727.1 - 1.6e-16 60.1 0.0 2.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Med21 PF11221.3 EME26728.1 - 0.015 15.2 10.1 0.12 12.3 7.0 2.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Cauli_DNA-bind PF03310.8 EME26728.1 - 0.044 13.6 0.2 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Med11 PF10280.4 EME26728.1 - 0.063 13.3 2.6 0.083 12.9 1.2 1.8 2 0 0 2 2 2 0 Mediator complex protein DUF3293 PF11697.3 EME26728.1 - 0.064 13.3 0.8 2.1 8.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) GBP_C PF02841.9 EME26728.1 - 0.068 12.3 6.3 0.083 12.0 3.8 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Laminin_II PF06009.7 EME26728.1 - 0.08 12.6 1.3 0.13 12.0 0.9 1.4 1 0 0 1 1 1 0 Laminin Domain II VWA_N PF08399.6 EME26728.1 - 0.12 12.9 0.2 0.2 12.2 0.1 1.4 1 1 0 1 1 1 0 VWA N-terminal APG6 PF04111.7 EME26728.1 - 0.39 9.7 7.4 0.48 9.4 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EME26728.1 - 0.51 9.9 9.0 0.62 9.6 5.1 1.8 2 0 0 2 2 2 0 IncA protein OEP PF02321.13 EME26728.1 - 1 8.9 6.3 1.4 8.5 4.4 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF972 PF06156.8 EME26728.1 - 2.8 8.3 6.3 2.5 8.5 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EME26728.1 - 9.5 6.6 8.0 37 4.7 3.7 2.4 2 1 0 2 2 2 0 SlyX Ada3 PF10198.4 EME26729.1 - 0.00073 19.3 8.3 0.0016 18.2 5.7 1.6 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Phasin PF05597.6 EME26729.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Bot1p PF12298.3 EME26729.1 - 0.043 13.7 2.9 0.077 12.9 2.0 1.4 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein eIF_4G1 PF12152.3 EME26729.1 - 0.079 12.8 0.8 0.2 11.5 0.6 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 PPR PF01535.15 EME26730.1 - 2.6e-11 42.6 0.5 0.44 10.6 0.0 7.2 8 0 0 8 8 8 3 PPR repeat PPR_2 PF13041.1 EME26730.1 - 6.1e-09 35.7 0.0 0.0064 16.4 0.0 6.2 5 2 1 6 6 6 1 PPR repeat family PPR_3 PF13812.1 EME26730.1 - 1.1e-08 34.6 4.3 0.41 11.0 0.0 7.6 8 0 0 8 8 8 1 Pentatricopeptide repeat domain TPR_12 PF13424.1 EME26730.1 - 0.0023 17.8 3.1 0.11 12.4 0.9 3.7 4 1 1 5 5 5 2 Tetratricopeptide repeat PPR_1 PF12854.2 EME26730.1 - 0.027 13.9 0.3 3.7 7.1 0.1 3.5 4 0 0 4 4 4 0 PPR repeat UPF0147 PF03685.8 EME26730.1 - 0.044 13.6 0.2 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) BTAD PF03704.12 EME26730.1 - 0.21 11.8 3.1 4.5 7.5 0.4 3.8 3 1 2 5 5 5 0 Bacterial transcriptional activator domain Abhydrolase_6 PF12697.2 EME26731.1 - 5.9e-34 117.9 0.0 6.9e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME26731.1 - 2.8e-20 72.8 0.2 2.1e-19 70.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME26731.1 - 1.8e-13 50.4 0.0 3.1e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME26731.1 - 0.0001 22.1 0.1 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase EHN PF06441.7 EME26731.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus SMC_N PF02463.14 EME26732.1 - 5.3e-46 156.6 39.5 4.2e-45 153.6 27.4 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME26732.1 - 1.9e-27 95.5 0.1 3.6e-26 91.4 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EME26732.1 - 1.6e-13 51.4 23.9 1.6e-13 51.4 16.6 7.1 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EME26732.1 - 2.4e-10 40.8 26.0 2.2e-07 31.1 1.8 3.9 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EME26732.1 - 6.2e-06 25.6 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME26732.1 - 0.00014 21.6 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EME26732.1 - 0.053 13.7 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EME26732.1 - 0.42 9.9 3.6 2.4 7.5 0.0 3.8 4 1 1 5 5 5 0 AAA domain DUF1212 PF06738.7 EME26732.1 - 0.86 9.0 1.7 30 4.0 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Gly_transf_sug PF04488.10 EME26733.1 - 1.9e-09 37.8 0.0 3.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EME26733.1 - 0.0001 21.5 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EME26733.1 - 0.00049 18.7 0.0 0.00071 18.1 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Gb3_synth PF04572.7 EME26733.1 - 0.013 15.1 0.7 0.18 11.4 0.5 2.2 1 1 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region RHD3 PF05879.7 EME26735.1 - 6.7e-81 272.3 3.0 8.2e-81 272.0 2.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF258 PF03193.11 EME26735.1 - 0.00064 18.9 0.1 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EME26735.1 - 0.00073 19.4 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME26735.1 - 0.007 16.2 0.1 0.007 16.2 0.0 1.9 2 0 0 2 2 1 1 Dynamin family AAA_14 PF13173.1 EME26735.1 - 0.013 15.3 0.5 0.032 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EME26735.1 - 0.014 15.5 0.9 0.049 13.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EME26735.1 - 0.021 15.3 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EME26735.1 - 0.022 14.4 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EME26735.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME26735.1 - 0.026 14.8 4.3 0.046 14.0 0.0 2.6 2 1 0 2 2 2 0 ABC transporter GBP PF02263.14 EME26735.1 - 0.028 13.4 0.0 0.028 13.4 0.0 2.6 4 0 0 4 4 4 0 Guanylate-binding protein, N-terminal domain AAA_17 PF13207.1 EME26735.1 - 0.037 14.8 0.3 0.33 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EME26735.1 - 0.05 13.1 0.7 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EME26735.1 - 0.07 12.1 0.4 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EME26735.1 - 0.078 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EME26735.1 - 0.085 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EME26735.1 - 0.086 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EME26735.1 - 0.094 11.5 0.0 0.26 10.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EME26735.1 - 0.099 12.5 1.9 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME26735.1 - 0.11 12.7 0.4 0.47 10.7 0.0 2.2 2 1 1 3 3 2 0 AAA domain AAA_10 PF12846.2 EME26735.1 - 0.19 11.1 4.8 0.16 11.4 0.5 2.5 1 1 1 2 2 2 0 AAA-like domain Activator_LAG-3 PF11498.3 EME26735.1 - 0.41 9.3 14.9 0.64 8.7 10.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pedibin PF08182.6 EME26735.1 - 0.5 9.8 3.1 0.64 9.5 0.9 2.1 2 0 0 2 2 2 0 Pedibin/Hym-346 family AAA_16 PF13191.1 EME26735.1 - 1.3 8.9 5.8 1.1 9.2 0.1 3.0 2 2 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EME26735.1 - 7.4 6.8 8.7 29 4.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain RHD3 PF05879.7 EME26736.1 - 6.2e-79 265.8 2.5 7.6e-79 265.5 1.7 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF258 PF03193.11 EME26736.1 - 0.00065 18.9 0.1 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EME26736.1 - 0.00074 19.4 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME26736.1 - 0.007 16.1 0.1 0.007 16.1 0.0 1.9 2 0 0 2 2 1 1 Dynamin family AAA_14 PF13173.1 EME26736.1 - 0.013 15.3 0.5 0.032 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EME26736.1 - 0.014 15.5 0.9 0.049 13.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EME26736.1 - 0.021 15.2 0.0 0.056 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EME26736.1 - 0.022 14.4 0.0 0.37 10.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EME26736.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain GBP PF02263.14 EME26736.1 - 0.028 13.4 0.0 0.028 13.4 0.0 2.6 4 0 0 4 4 4 0 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.22 EME26736.1 - 0.029 14.6 4.3 0.047 13.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EME26736.1 - 0.038 14.8 0.3 0.34 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EME26736.1 - 0.055 12.9 0.7 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EME26736.1 - 0.071 12.1 0.4 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EME26736.1 - 0.078 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EME26736.1 - 0.085 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EME26736.1 - 0.087 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME26736.1 - 0.094 12.1 3.7 0.13 11.6 0.2 2.5 1 1 1 2 2 2 0 AAA-like domain NB-ARC PF00931.17 EME26736.1 - 0.095 11.5 0.0 0.27 10.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EME26736.1 - 0.1 12.5 1.9 0.12 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EME26736.1 - 0.12 12.6 0.2 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Activator_LAG-3 PF11498.3 EME26736.1 - 0.41 9.3 14.9 0.65 8.6 10.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pedibin PF08182.6 EME26736.1 - 0.51 9.8 3.1 0.64 9.5 0.9 2.1 2 0 0 2 2 2 0 Pedibin/Hym-346 family AAA_16 PF13191.1 EME26736.1 - 1.8 8.5 6.1 1.1 9.2 0.1 3.0 2 2 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EME26736.1 - 4.8 7.4 7.9 29 4.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Robl_LC7 PF03259.12 EME26737.1 - 0.00032 20.1 0.1 0.022 14.3 0.1 2.2 1 1 0 1 1 1 1 Roadblock/LC7 domain PAP_fibrillin PF04755.7 EME26738.1 - 0.00016 21.4 0.0 0.0024 17.6 0.0 2.3 1 1 0 1 1 1 1 PAP_fibrillin Trigger_N PF05697.8 EME26739.1 - 2.9e-26 91.9 0.1 2.9e-26 91.9 0.1 2.8 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.9 EME26739.1 - 3.6e-14 52.9 17.1 7.1e-14 51.9 11.8 1.5 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.23 EME26739.1 - 0.00039 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2854 PF11016.3 EME26739.1 - 0.14 11.7 2.8 0.3 10.5 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2854) zf-met PF12874.2 EME26739.1 - 0.95 9.7 4.5 0.33 11.2 0.9 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpeS PF09367.5 EME26740.1 - 2.5e-50 170.6 0.0 3.6e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 CpeS-like protein UPF0547 PF10571.4 EME26741.1 - 3.2e-07 29.9 16.5 0.00021 20.9 1.2 2.6 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 DZR PF12773.2 EME26741.1 - 5.6e-07 29.2 11.4 1.6e-06 27.8 8.0 1.7 1 1 0 1 1 1 1 Double zinc ribbon zf-FPG_IleRS PF06827.9 EME26741.1 - 0.001 18.6 3.5 0.046 13.3 0.0 3.4 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.1 EME26741.1 - 0.017 14.6 2.0 0.017 14.6 1.4 2.8 2 1 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 EME26741.1 - 0.055 13.2 6.1 0.37 10.5 0.6 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_5 PF13719.1 EME26741.1 - 0.21 11.2 15.2 12 5.6 2.0 4.1 2 1 1 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EME26741.1 - 0.4 9.9 15.5 0.071 12.3 1.2 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EME26741.1 - 0.9 9.2 16.9 21 4.8 2.6 4.1 2 1 1 3 3 3 0 zinc-ribbon domain zf-dskA_traR PF01258.12 EME26741.1 - 1.2 8.9 3.7 6.6 6.5 0.1 2.9 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_3 PF13920.1 EME26741.1 - 3.3 7.4 13.9 0.26 10.9 1.3 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 EME26742.1 - 0.00021 20.9 1.7 0.00021 20.9 1.2 1.9 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 DZR PF12773.2 EME26742.1 - 0.0072 16.1 13.3 0.019 14.7 2.0 1.5 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EME26742.1 - 0.0075 15.7 2.0 0.017 14.6 1.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 EME26742.1 - 0.039 13.1 1.8 0.07 12.3 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Bac_surface_Ag PF01103.18 EME26743.1 - 5.4e-20 72.0 0.1 8.2e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 Surface antigen MAT1 PF06391.8 EME26743.1 - 5.1e-16 58.8 8.7 1.4e-15 57.4 6.0 1.7 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Surf_Ag_VNR PF07244.10 EME26743.1 - 1.1e-06 28.9 4.3 0.044 14.1 0.1 3.6 3 0 0 3 3 3 2 Surface antigen variable number repeat POTRA_2 PF08479.6 EME26743.1 - 0.00082 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 POTRA domain, ShlB-type Nol1_Nop2_Fmu PF01189.12 EME26744.1 - 4e-15 55.9 0.0 7.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family DED PF01335.16 EME26744.1 - 0.12 12.5 1.9 0.5 10.5 0.1 2.8 2 0 0 2 2 2 0 Death effector domain Vps26 PF03643.10 EME26745.1 - 3.2e-105 350.8 1.8 3.7e-105 350.6 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EME26745.1 - 1.5e-05 24.8 1.5 0.0028 17.4 0.2 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_S15 PF00312.17 EME26746.1 - 1.3e-21 76.1 4.0 2.3e-21 75.3 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Gryzun PF07919.7 EME26746.1 - 0.0057 15.0 0.7 0.0067 14.8 0.5 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi NHR2 PF08788.6 EME26746.1 - 0.013 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 NHR2 domain like Mnd1 PF03962.10 EME26746.1 - 5.5 6.6 11.5 3.9 7.1 0.3 1.9 1 1 1 2 2 2 0 Mnd1 family Pirin PF02678.11 EME26747.1 - 4.3e-35 119.8 0.1 8.5e-35 118.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EME26747.1 - 1.4e-31 108.5 0.0 1.5e-30 105.3 0.0 2.3 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EME26747.1 - 0.013 14.9 0.9 0.84 9.1 0.4 2.4 2 0 0 2 2 2 0 Cupin domain KOW PF00467.24 EME26747.1 - 0.12 12.1 0.5 0.38 10.5 0.4 1.8 1 0 0 1 1 1 0 KOW motif Arf PF00025.16 EME26748.1 - 3.1e-58 195.8 0.1 3.5e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME26748.1 - 1.9e-14 53.3 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME26748.1 - 4.8e-14 51.8 4.3 5.9e-09 35.1 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME26748.1 - 8.3e-10 38.2 0.0 8.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME26748.1 - 4.8e-09 36.7 0.0 6.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME26748.1 - 6.2e-07 29.3 0.0 8.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EME26748.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EME26748.1 - 2.2e-06 27.2 0.0 5.4e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EME26748.1 - 4e-05 23.9 0.0 6.5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME26748.1 - 0.004 17.0 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME26748.1 - 0.0042 17.9 0.1 0.006 17.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EME26748.1 - 0.0078 15.3 0.0 0.017 14.2 0.0 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_16 PF13191.1 EME26748.1 - 0.039 13.9 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EME26748.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EME26748.1 - 0.057 13.5 0.0 0.099 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.26 EME26749.1 - 3e-20 71.9 8.6 1.7e-11 43.9 0.3 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME26749.1 - 6.6e-20 70.9 8.8 3.4e-13 49.4 2.5 4.6 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 EME26749.1 - 1.2e-15 57.3 8.8 1.2e-15 57.3 6.1 3.6 4 0 0 4 4 4 1 pre-mRNA splicing factor component NPP1 PF05630.6 EME26749.1 - 0.11 12.1 0.4 0.55 9.9 0.1 2.1 2 0 0 2 2 2 0 Necrosis inducing protein (NPP1) Avl9 PF09794.4 EME26750.1 - 1.2e-55 188.5 0.0 2.5e-51 174.3 0.0 3.3 2 1 0 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 EME26750.1 - 1.9e-07 30.6 0.6 3.5e-06 26.5 0.4 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 EME26750.1 - 0.00065 19.7 0.0 0.01 15.8 0.0 2.3 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.16 EME26750.1 - 0.015 14.9 1.4 0.33 10.6 1.0 2.6 1 1 0 1 1 1 0 DENN (AEX-3) domain Nic96 PF04097.9 EME26751.1 - 2.5e-96 323.1 5.0 5.7e-96 322.0 3.5 1.5 1 0 0 1 1 1 1 Nup93/Nic96 EssA PF10661.4 EME26752.1 - 0.36 10.4 2.5 0.64 9.6 1.8 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA S1 PF00575.18 EME26753.1 - 2.4e-32 110.8 6.1 1.1e-20 73.4 0.4 2.5 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.1 EME26753.1 - 2.8e-07 30.3 1.7 0.0027 17.5 0.1 2.5 2 1 0 2 2 2 2 S1 domain DUF2140 PF09911.4 EME26753.1 - 0.0014 17.8 0.7 0.94 8.6 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2140) Myb_DNA-binding PF00249.26 EME26754.1 - 9.2e-09 35.2 0.4 1.7e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME26754.1 - 0.025 14.6 1.2 0.052 13.6 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain LRR_4 PF12799.2 EME26755.1 - 6.9e-10 38.3 31.5 9.2e-07 28.3 2.0 5.3 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME26755.1 - 2.2e-09 36.8 21.1 2.5e-06 27.1 5.3 4.5 3 1 1 4 4 4 2 Leucine rich repeat EF-hand_1 PF00036.27 EME26755.1 - 0.00048 19.2 0.5 0.0015 17.6 0.4 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EME26755.1 - 0.0008 18.9 0.5 0.0008 18.9 0.4 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 EME26755.1 - 0.014 15.5 0.1 0.057 13.5 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EME26755.1 - 0.014 14.7 0.1 0.036 13.4 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EME26755.1 - 0.018 14.9 0.2 0.075 12.9 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain LRR_7 PF13504.1 EME26755.1 - 3.6 8.1 10.3 34 5.2 0.2 5.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EME26755.1 - 8.4 6.8 25.8 3.8 7.9 0.1 6.8 6 0 0 6 6 6 0 Leucine Rich Repeat ANTH PF07651.11 EME26756.1 - 1.1e-26 93.1 0.5 1.6e-26 92.6 0.4 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EME26756.1 - 6.2e-06 26.0 0.1 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 ENTH domain MAP65_ASE1 PF03999.7 EME26757.1 - 3.2e-41 141.6 63.7 7.5e-41 140.4 44.1 1.6 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Vps51 PF08700.6 EME26757.1 - 3.5 7.5 14.2 0.082 12.7 0.6 4.3 3 0 0 3 3 3 0 Vps51/Vps67 Vac_Fusion PF02346.11 EME26757.1 - 5.7 6.4 12.6 2.5 7.5 0.3 5.0 6 0 0 6 6 6 0 Chordopoxvirus fusion protein LRR_4 PF12799.2 EME26758.1 - 1.4e-21 75.6 25.1 5.1e-08 32.3 1.2 6.0 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME26758.1 - 2.8e-18 65.3 19.4 1.5e-07 31.0 0.2 3.6 2 1 2 4 4 4 4 Leucine rich repeat Ank_2 PF12796.2 EME26758.1 - 6e-11 42.5 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME26758.1 - 1.5e-10 40.3 0.0 1.7e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EME26758.1 - 3.1e-09 37.0 0.0 0.0033 17.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME26758.1 - 1.1e-08 35.0 0.0 4.9e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME26758.1 - 3.8e-08 32.8 0.0 0.00034 20.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat LRR_1 PF00560.28 EME26758.1 - 6.7e-07 28.4 18.6 0.4 10.8 0.0 8.2 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.1 EME26758.1 - 0.00038 20.0 5.3 0.0025 17.3 0.7 2.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 EME26758.1 - 0.00039 20.1 16.5 0.8 10.1 0.0 7.4 7 1 0 7 7 7 2 Leucine rich repeat Flp_Fap PF04964.9 EME26758.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Flp/Fap pilin component LRR_6 PF13516.1 EME26758.1 - 0.74 10.0 15.7 3 8.2 0.2 5.6 6 0 0 6 6 6 0 Leucine Rich repeat UQ_con PF00179.21 EME26759.1 - 7.3e-16 57.8 0.0 7.8e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EME26759.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain MFS_1 PF07690.11 EME26760.1 - 6.8e-17 61.2 8.5 6.8e-17 61.2 5.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME26760.1 - 2.1e-12 46.2 18.0 2.9e-12 45.7 7.3 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EME26760.1 - 1.6e-08 33.7 0.1 2.6e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 PUCC protein Nuc_H_symport PF03825.11 EME26760.1 - 0.1 11.3 0.0 0.1 11.3 0.0 3.4 2 1 0 2 2 2 0 Nucleoside H+ symporter WAC_Acf1_DNA_bd PF10537.4 EME26761.1 - 6.9e-27 93.6 2.0 1.2e-26 92.7 0.4 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EME26761.1 - 9.3e-08 31.7 0.9 2.9e-07 30.1 0.4 2.0 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 EME26761.1 - 0.0021 17.8 0.2 0.0062 16.4 0.2 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EME26761.1 - 0.045 13.7 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 PRP1_N PF06424.7 EME26762.1 - 1.4e-38 132.2 10.0 2.9e-35 121.4 4.2 3.1 4 0 0 4 4 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EME26762.1 - 4e-27 92.2 26.7 0.0022 18.4 0.0 13.9 7 4 8 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EME26762.1 - 1.9e-12 47.3 10.3 0.016 15.5 0.3 8.6 7 3 2 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME26762.1 - 2.2e-11 44.0 21.9 0.033 14.8 1.0 7.9 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME26762.1 - 1.3e-08 34.3 6.1 0.067 12.8 0.0 7.5 5 3 4 9 9 9 4 TPR repeat TPR_2 PF07719.12 EME26762.1 - 1.4e-05 24.6 4.9 4.3 7.5 0.0 8.2 11 1 0 11 11 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME26762.1 - 4.3e-05 23.3 0.0 16 5.9 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME26762.1 - 0.0058 16.5 11.8 0.017 15.0 0.0 5.7 4 1 2 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EME26762.1 - 0.0059 16.3 10.2 0.3 10.7 0.1 5.5 4 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 EME26762.1 - 0.009 16.4 7.4 39 4.9 0.0 8.2 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME26762.1 - 0.068 12.9 0.0 54 3.9 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DivIC PF04977.10 EME26762.1 - 1.1 8.7 7.3 5 6.6 0.1 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 EME26763.1 - 8e-05 22.0 32.1 0.00023 20.5 7.1 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) bZIP_2 PF07716.10 EME26763.1 - 0.0027 17.4 9.6 0.0027 17.4 6.6 4.5 4 0 0 4 4 4 2 Basic region leucine zipper Reo_sigmaC PF04582.7 EME26763.1 - 0.0048 16.1 13.2 0.01 15.0 3.6 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EME26763.1 - 0.013 15.4 1.0 0.013 15.4 0.7 3.9 3 0 0 3 3 3 0 bZIP transcription factor CALCOCO1 PF07888.6 EME26763.1 - 0.092 11.0 37.0 0.0082 14.4 22.1 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TBPIP PF07106.8 EME26763.1 - 0.17 11.3 37.7 0.45 10.0 5.0 3.3 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EME26763.1 - 0.21 11.4 44.6 0.19 11.6 12.9 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 EME26763.1 - 0.61 9.4 29.4 3.3 7.0 4.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) BLOC1_2 PF10046.4 EME26763.1 - 0.88 9.7 24.5 0.027 14.5 4.4 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EME26763.1 - 0.94 9.5 38.2 0.26 11.3 9.3 3.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.14 EME26763.1 - 1.2 6.8 46.3 0.011 13.5 26.6 1.5 2 0 0 2 2 2 0 Myosin tail DUF904 PF06005.7 EME26763.1 - 3.1 8.1 44.9 0.44 10.8 6.5 4.3 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Lectin_N PF03954.9 EME26763.1 - 3.1 7.1 13.7 2.4 7.5 1.8 3.1 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain IncA PF04156.9 EME26763.1 - 7.1 6.1 52.9 0.2 11.2 20.5 2.5 2 1 1 3 3 3 0 IncA protein NPV_P10 PF05531.7 EME26763.1 - 8.5 6.7 17.5 13 6.1 1.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EME26763.1 - 9.8 6.0 47.5 1.4 8.7 17.8 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_carr PF00153.22 EME26764.1 - 1.5e-67 223.3 0.4 1e-22 79.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 EME26765.1 - 8.3e-41 139.2 0.0 2.9e-40 137.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME26765.1 - 4.3e-25 87.3 0.1 1.2e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME26765.1 - 0.00035 19.4 0.0 0.00053 18.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EME26765.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME26765.1 - 0.049 13.7 2.2 0.89 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain zf-CCCH PF00642.19 EME26766.1 - 3.5e-24 83.9 18.5 2.4e-13 49.3 2.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME26766.1 - 0.00016 21.5 9.4 0.061 13.3 1.6 3.1 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EME26766.1 - 0.6 9.7 4.5 9.3 5.9 0.5 2.3 1 1 1 2 2 2 0 LRV protein FeS4 cluster Aminotran_1_2 PF00155.16 EME26767.1 - 2.4e-62 211.0 0.0 3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME26767.1 - 6.2e-07 28.4 0.0 1.8e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME26767.1 - 6.8e-06 25.4 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EME26767.1 - 5e-05 22.5 0.0 8.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME26767.1 - 0.00037 18.9 0.0 0.00072 17.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EME26768.1 - 1.2e-57 195.5 0.0 6.7e-28 97.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.14 EME26768.1 - 0.00016 20.5 0.0 0.00048 18.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME26768.1 - 0.00095 18.2 0.0 0.0025 16.9 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME26768.1 - 0.0082 14.4 0.0 0.016 13.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EME26768.1 - 0.099 11.7 0.0 0.34 10.0 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase TFIIF_beta PF02270.10 EME26769.1 - 1e-18 68.1 3.0 1.6e-18 67.5 1.8 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 EME26769.1 - 4.3e-05 23.0 0.1 5.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit PALP PF00291.20 EME26770.1 - 9.7e-44 149.8 0.1 1.7e-43 149.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Carb_kinase PF01256.12 EME26772.1 - 1.5e-55 188.1 0.0 1.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EME26772.1 - 8.1e-05 21.9 0.0 0.00021 20.5 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 EME26773.1 - 1.4e-55 188.1 0.0 1.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EME26773.1 - 8e-05 21.9 0.0 0.0002 20.6 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase SHNi-TPR PF10516.4 EME26774.1 - 1.2e-07 30.8 2.0 7.6e-07 28.2 0.1 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EME26774.1 - 0.0056 16.3 2.4 4 7.1 0.0 3.1 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.1 EME26774.1 - 0.013 15.4 1.1 1.4 8.8 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_18 PF13512.1 EME26774.1 - 0.029 14.4 0.9 0.82 9.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1771 PF08590.5 EME26774.1 - 0.036 14.0 2.1 0.2 11.6 1.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) TPR_7 PF13176.1 EME26774.1 - 0.044 13.5 5.1 26 4.9 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME26774.1 - 0.052 14.2 1.4 36 5.3 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EME26774.1 - 0.078 12.4 2.8 0.045 13.1 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 EME26774.1 - 0.22 11.5 5.6 6.4 6.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME26774.1 - 0.29 11.8 4.7 12 6.7 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TP53IP5 PF15331.1 EME26774.1 - 2.1 8.1 5.0 5 6.9 3.4 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Cullin_binding PF03556.10 EME26775.1 - 3.7e-37 127.0 2.0 5.2e-37 126.5 1.4 1.2 1 0 0 1 1 1 1 Cullin binding GP41 PF00517.12 EME26775.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.3 1 1 0 1 1 1 0 Retroviral envelope protein ABC_tran PF00005.22 EME26776.1 - 1.6e-23 83.5 0.0 2.7e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME26776.1 - 1.9e-15 57.5 0.3 1.1e-08 35.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 EME26776.1 - 0.00043 19.7 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME26776.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME26776.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EME26776.1 - 0.0082 15.4 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.1 EME26776.1 - 0.011 16.2 0.0 0.079 13.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) UPF0079 PF02367.12 EME26776.1 - 0.025 14.1 0.1 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 adh_short PF00106.20 EME26777.1 - 5.7e-23 81.6 0.4 7.1e-23 81.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME26777.1 - 9.2e-08 31.9 0.3 1.3e-07 31.5 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME26777.1 - 1.7e-07 31.2 0.6 2.4e-07 30.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME26777.1 - 0.0028 17.6 0.2 0.0061 16.5 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 EME26777.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Wax2_C PF12076.3 EME26777.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain RP1-2 PF12042.3 EME26777.1 - 0.12 11.9 1.7 0.76 9.4 0.5 2.3 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain Eno-Rase_NADH_b PF12242.3 EME26777.1 - 0.23 11.2 1.1 0.51 10.1 0.5 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SERTA PF06031.8 EME26777.1 - 6.2 6.2 10.8 4.4 6.6 0.0 3.3 3 0 0 3 3 3 0 SERTA motif EMP70 PF02990.11 EME26778.1 - 1.9e-118 396.2 13.4 2.4e-118 395.8 9.3 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.11 EME26778.1 - 0.0037 16.0 16.4 0.0037 16.0 11.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sld5 PF05916.6 EME26780.1 - 9.5e-06 25.8 0.2 1.6e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Ribophorin_I PF04597.9 EME26781.1 - 3.8e-90 302.4 0.3 4.9e-90 302.1 0.2 1.1 1 0 0 1 1 1 1 Ribophorin I TPR_1 PF00515.23 EME26782.1 - 1.8e-38 128.6 29.8 7.3e-07 28.5 0.3 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EME26782.1 - 4.2e-32 109.6 32.1 3.6e-10 39.3 4.0 6.7 5 1 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 EME26782.1 - 4.2e-30 101.1 28.4 5.6e-05 22.7 1.5 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 EME26782.1 - 2.1e-23 80.3 24.5 0.0015 18.1 0.1 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EME26782.1 - 3e-22 78.5 32.4 9e-13 48.1 1.5 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EME26782.1 - 1.8e-19 69.4 23.8 1.4e-06 28.1 2.8 7.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME26782.1 - 3.7e-19 68.8 18.2 2.3e-05 24.9 0.1 7.1 4 1 4 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EME26782.1 - 2.4e-18 64.7 18.9 0.00054 19.9 0.1 10.2 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME26782.1 - 4.4e-16 57.9 10.1 0.059 14.0 0.0 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME26782.1 - 5.3e-15 55.5 17.3 7.8e-05 22.9 0.5 8.4 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 EME26782.1 - 6.3e-12 45.1 18.2 1.3 9.6 0.1 9.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME26782.1 - 2.2e-06 27.4 13.2 0.091 12.6 0.1 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME26782.1 - 2.1e-05 23.9 21.1 0.026 14.3 0.0 8.0 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 EME26782.1 - 2.1e-05 24.5 0.5 0.0021 18.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 EME26782.1 - 0.051 12.3 0.2 1.5 7.5 0.0 2.8 1 1 3 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) VWA_2 PF13519.1 EME26783.1 - 3.9e-14 53.1 0.1 8.9e-14 51.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 EME26783.1 - 5.2e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.15 EME26783.1 - 0.00091 18.5 2.6 0.00091 18.5 1.8 3.4 4 0 0 4 4 4 2 Ubiquitin interaction motif Strabismus PF06638.6 EME26784.1 - 0.32 9.2 7.0 0.29 9.4 4.8 1.0 1 0 0 1 1 1 0 Strabismus protein Peptidase_M50 PF02163.17 EME26784.1 - 4.4 6.2 5.3 0.71 8.8 0.9 1.6 2 1 0 2 2 2 0 Peptidase family M50 Tic20 PF09685.5 EME26784.1 - 7.4 6.6 17.1 0.13 12.2 6.9 1.7 2 0 0 2 2 2 0 Tic20-like protein Peptidase_M16 PF00675.15 EME26785.1 - 1.9e-49 167.2 0.3 3.2e-49 166.5 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EME26785.1 - 2.3e-38 131.7 0.0 8.3e-35 120.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain WLM PF08325.5 EME26786.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 WLM domain SAC3_GANP PF03399.11 EME26787.1 - 3.4e-44 150.8 0.6 5.8e-44 150.0 0.4 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WW PF00397.21 EME26787.1 - 8.1e-08 31.9 7.2 2.8e-05 23.8 0.4 3.3 3 0 0 3 3 3 2 WW domain WD40 PF00400.27 EME26788.1 - 1.9e-23 81.4 4.6 3.1e-07 30.0 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME26788.1 - 5.6e-05 22.0 0.5 0.026 13.2 0.0 2.6 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EME26788.1 - 0.054 11.6 1.3 3.2 5.7 0.0 2.3 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME26788.1 - 0.066 13.5 1.7 11 6.4 0.0 3.3 2 1 1 3 3 3 0 PQQ-like domain Dynamin_N PF00350.18 EME26789.1 - 1.1e-25 90.3 3.6 1.1e-11 44.9 0.0 3.6 3 1 1 4 4 4 2 Dynamin family MMR_HSR1 PF01926.18 EME26789.1 - 2.3e-15 56.5 0.0 6.8e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME26789.1 - 3.2e-07 30.8 0.0 1.2e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EME26789.1 - 1.1e-06 28.2 0.1 7.5e-05 22.2 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME26789.1 - 0.0002 20.6 0.1 0.65 9.2 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B IIGP PF05049.8 EME26789.1 - 0.00042 19.2 0.4 0.011 14.5 0.3 2.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EME26789.1 - 0.0049 16.0 0.0 0.028 13.5 0.0 2.2 1 1 0 1 1 1 1 AIG1 family Ras PF00071.17 EME26789.1 - 0.01 15.2 0.0 0.12 11.7 0.0 2.3 1 1 0 1 1 1 0 Ras family TipAS PF07739.8 EME26789.1 - 0.013 15.8 0.2 0.85 9.9 0.0 2.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF258 PF03193.11 EME26789.1 - 0.03 13.4 0.1 0.28 10.3 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EME26789.1 - 0.054 13.1 0.5 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase PduV-EutP PF10662.4 EME26789.1 - 0.077 12.4 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Spore_IV_A PF09547.5 EME26789.1 - 0.09 11.4 0.2 2.5 6.6 0.0 2.6 3 0 0 3 3 3 0 Stage IV sporulation protein A (spore_IV_A) AAA_10 PF12846.2 EME26789.1 - 0.13 11.6 1.7 0.53 9.6 0.1 2.8 3 1 0 3 3 3 0 AAA-like domain SHS2_Rpb7-N PF03876.12 EME26790.1 - 1e-12 47.9 0.1 2.3e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EME26790.1 - 6.1e-10 39.0 1.5 8.3e-10 38.6 0.1 1.9 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EME26790.1 - 3.4e-06 27.2 0.0 5.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 AAA_2 PF07724.9 EME26791.1 - 3.1e-50 170.4 0.0 7.2e-48 162.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EME26791.1 - 1.1e-25 89.2 0.3 3.1e-25 87.8 0.2 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EME26791.1 - 3.5e-22 79.0 0.1 1.2e-12 48.2 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME26791.1 - 5.9e-16 58.9 7.0 1.6e-05 24.9 0.0 4.5 3 2 1 4 4 4 3 AAA ATPase domain AAA_5 PF07728.9 EME26791.1 - 2.6e-14 53.1 0.0 2.5e-09 36.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME26791.1 - 2.2e-10 40.7 0.6 0.0017 18.4 0.0 4.0 3 2 1 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EME26791.1 - 5.1e-07 29.6 6.2 0.00087 19.0 0.2 4.3 3 2 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 EME26791.1 - 6.8e-07 29.6 2.1 0.041 14.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EME26791.1 - 3.4e-06 27.8 7.5 0.0011 19.8 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EME26791.1 - 9.4e-06 25.5 0.0 0.11 12.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EME26791.1 - 1.7e-05 24.3 0.0 0.29 10.5 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME26791.1 - 2.2e-05 23.6 0.1 0.021 14.0 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EME26791.1 - 3.3e-05 23.9 3.7 0.73 9.7 0.0 4.3 3 2 1 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 EME26791.1 - 5.2e-05 23.1 0.1 0.0084 16.0 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EME26791.1 - 7.4e-05 23.1 9.1 1.7 8.9 7.8 2.9 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EME26791.1 - 8.7e-05 22.0 0.0 0.028 13.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 EME26791.1 - 0.00027 20.0 0.5 0.48 9.4 0.0 3.6 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME26791.1 - 0.00028 20.5 0.0 0.052 13.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EME26791.1 - 0.0004 20.5 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EME26791.1 - 0.00073 19.2 0.0 0.093 12.3 0.0 2.9 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EME26791.1 - 0.001 19.3 0.3 0.73 10.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter DUF815 PF05673.8 EME26791.1 - 0.0017 17.3 0.1 0.52 9.1 0.1 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF815) DUF258 PF03193.11 EME26791.1 - 0.0018 17.4 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EME26791.1 - 0.0035 16.9 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME26791.1 - 0.0048 16.4 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EME26791.1 - 0.0068 15.8 5.9 0.12 11.7 0.0 3.5 3 2 0 3 3 2 1 AAA domain MobB PF03205.9 EME26791.1 - 0.0076 15.9 0.0 0.51 10.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IncA PF04156.9 EME26791.1 - 0.0091 15.6 9.2 0.02 14.5 6.4 1.5 1 0 0 1 1 1 1 IncA protein AAA_33 PF13671.1 EME26791.1 - 0.011 15.5 0.7 2.7 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EME26791.1 - 0.013 15.0 0.0 0.37 10.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EME26791.1 - 0.027 14.9 0.0 1.7 9.1 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein NTPase_1 PF03266.10 EME26791.1 - 0.031 14.0 0.1 11 5.7 0.0 2.9 3 0 0 3 3 3 0 NTPase UPF0079 PF02367.12 EME26791.1 - 0.035 13.7 0.0 9.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EME26791.1 - 0.053 13.1 0.0 16 5.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EME26791.1 - 0.073 12.4 0.0 2.7 7.4 0.0 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EME26791.1 - 0.093 12.1 3.0 5.9 6.2 0.0 3.9 4 1 1 5 5 4 0 AAA-like domain PduV-EutP PF10662.4 EME26791.1 - 0.13 11.7 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rap1-DNA-bind PF09197.5 EME26792.1 - 1.2 9.7 4.5 10 6.6 0.3 2.7 3 0 0 3 3 3 0 Rap1, DNA-binding ELMO_CED12 PF04727.8 EME26793.1 - 0.074 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 ELMO/CED-12 family E2F_TDP PF02319.15 EME26794.1 - 2.6e-10 39.7 0.2 6.2e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Trehalose_PPase PF02358.11 EME26795.1 - 2.5e-40 137.8 0.0 7e-31 106.9 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.7 EME26795.1 - 0.0013 18.3 0.0 0.0024 17.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME26795.1 - 0.011 15.9 0.2 0.047 13.8 0.2 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MAAL_C PF07476.6 EME26795.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus C2 PF00168.25 EME26796.1 - 1.6e-07 31.0 0.0 3.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF2404 PF10296.4 EME26796.1 - 0.00019 21.4 0.2 0.00065 19.7 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF4449 PF14613.1 EME26796.1 - 0.081 12.8 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Fe_bilin_red PF05996.7 EME26797.1 - 3.3e-61 206.6 0.8 4.3e-61 206.2 0.6 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Nefa_Nip30_N PF10187.4 EME26798.1 - 0.00049 20.2 11.5 0.00049 20.2 8.0 2.2 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2098 PF09871.4 EME26798.1 - 1.7 8.6 6.0 0.52 10.2 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) SpoIIIAH PF12685.2 EME26798.1 - 1.9 7.9 5.2 0.72 9.3 2.1 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Enkurin PF13864.1 EME26798.1 - 4.8 7.4 10.8 55 4.0 0.0 3.2 2 1 0 2 2 2 0 Calmodulin-binding Glyco_hydr_30_2 PF14587.1 EME26799.1 - 1.2e-32 113.3 0.3 4.9e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 EME26799.1 - 1.2e-06 27.0 0.1 1.9e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Thiolase_N PF00108.18 EME26800.1 - 1.7e-93 312.4 0.1 2.4e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME26800.1 - 1.9e-45 153.2 0.6 1.9e-45 153.2 0.4 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME26800.1 - 0.00037 20.0 0.8 0.00037 20.0 0.6 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain LSM PF01423.17 EME26801.1 - 1.1e-13 50.4 0.0 1.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME26801.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.5 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM PF01423.17 EME26802.1 - 1.4e-13 50.1 0.0 2.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME26802.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain PRP38 PF03371.10 EME26803.1 - 4e-62 208.8 0.3 5.9e-62 208.3 0.2 1.2 1 0 0 1 1 1 1 PRP38 family DNA_pol_B_exo1 PF03104.14 EME26803.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain AbiH PF14253.1 EME26803.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Ribosomal_L3 PF00297.17 EME26804.1 - 1.1e-119 398.6 6.3 1.4e-119 398.3 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.17 EME26805.1 - 1.1e-119 398.6 6.3 1.4e-119 398.3 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 tRNA_Me_trans PF03054.11 EME26807.1 - 2.2e-107 358.7 0.0 2.7e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.10 EME26807.1 - 2.4e-17 62.7 0.0 3.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Asn_synthase PF00733.16 EME26807.1 - 2.4e-05 23.9 0.0 5.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EME26807.1 - 0.00027 20.4 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EME26807.1 - 0.0066 15.7 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC DUF2039 PF10217.4 EME26807.1 - 0.0083 16.1 0.3 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) NAD_synthase PF02540.12 EME26807.1 - 0.033 13.0 0.4 8.5 5.1 0.0 2.8 2 1 0 2 2 2 0 NAD synthase Acetyltransf_13 PF13880.1 EME26808.1 - 7.6e-18 64.0 0.1 1.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EME26808.1 - 6.2e-14 51.2 0.4 1.5e-13 50.0 0.3 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO CactinC_cactus PF09732.4 EME26809.1 - 1.7e-55 185.9 5.5 3.6e-55 184.8 3.8 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EME26809.1 - 2.7e-23 82.2 8.3 2.2e-14 53.1 0.7 3.7 3 2 1 5 5 5 2 Conserved mid region of cactin Mnd1 PF03962.10 EME26811.1 - 1.3e-60 204.3 2.6 1.4e-60 204.1 1.8 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 EME26811.1 - 4.5e-05 23.0 1.8 6.1e-05 22.6 1.2 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUR PF01475.14 EME26811.1 - 0.00087 19.2 0.1 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family Cortex-I_coil PF09304.5 EME26811.1 - 0.0021 18.0 5.6 0.0037 17.2 3.9 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil DNA_topoisoIV PF00521.15 EME26811.1 - 0.016 14.0 0.2 0.016 14.0 0.2 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Penicillinase_R PF03965.11 EME26811.1 - 0.022 14.8 0.1 0.035 14.1 0.0 1.5 1 1 0 1 1 1 0 Penicillinase repressor Cnd3 PF12719.2 EME26811.1 - 0.041 12.8 0.5 0.05 12.5 0.3 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF2205 PF10224.4 EME26811.1 - 0.07 12.7 2.2 0.16 11.5 1.5 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Fungal_trans_2 PF11951.3 EME26811.1 - 0.093 11.3 1.5 0.12 10.9 1.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain FAM117 PF15388.1 EME26811.1 - 0.097 11.8 0.6 0.13 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 TPR_11 PF13414.1 EME26812.1 - 6.8e-18 64.0 2.8 3.3e-11 42.6 0.1 3.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME26812.1 - 5.7e-15 54.1 1.7 0.00021 20.7 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME26812.1 - 8.4e-14 50.3 5.5 0.0012 18.6 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME26812.1 - 5.4e-12 46.0 0.4 5.9e-05 23.6 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME26812.1 - 1.3e-10 40.3 1.0 0.01 15.5 0.1 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME26812.1 - 1.3e-10 40.6 4.2 0.00045 20.2 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME26812.1 - 1.8e-09 37.3 1.8 0.00052 19.8 0.1 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME26812.1 - 4.2e-08 33.1 3.8 0.042 14.4 0.0 5.7 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME26812.1 - 5.9e-07 29.7 1.0 1.2e-05 25.4 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME26812.1 - 2.1e-05 24.2 0.0 0.061 13.1 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 EME26812.1 - 0.00025 20.8 3.4 5 7.3 0.1 4.9 3 1 1 4 4 4 1 PPR repeat Apc3 PF12895.2 EME26812.1 - 0.00057 19.9 0.8 0.076 13.1 0.1 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EME26812.1 - 0.0016 17.2 0.1 0.0047 15.7 0.1 1.8 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 EME26812.1 - 0.0023 17.5 7.4 24 5.0 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EME26812.1 - 0.0035 17.4 0.4 0.061 13.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ist1 PF03398.9 EME26812.1 - 0.0048 16.3 0.1 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Alkyl_sulf_dimr PF14863.1 EME26812.1 - 0.014 15.6 0.1 0.039 14.1 0.1 1.7 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 EME26812.1 - 0.03 14.7 1.0 11 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 EME26812.1 - 0.053 13.1 5.6 2.1 7.9 0.0 4.0 3 1 1 4 4 4 0 Region in Clathrin and VPS TPR_10 PF13374.1 EME26812.1 - 0.18 11.7 0.9 4.5 7.3 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 EME26812.1 - 0.21 11.5 3.4 11 6.1 0.1 3.4 3 1 1 4 4 2 0 PPR repeat family PspA_IM30 PF04012.7 EME26812.1 - 0.83 8.9 6.1 0.84 8.9 0.5 2.6 3 0 0 3 3 3 0 PspA/IM30 family Rad60-SLD PF11976.3 EME26814.1 - 2.9e-12 46.0 0.0 4.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME26814.1 - 0.0087 15.4 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 EME26814.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG TCR PF03638.10 EME26815.1 - 6.5e-27 93.1 60.8 3.4e-14 52.4 15.3 3.0 3 0 0 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain ArsB PF02040.10 EME26816.1 - 2.4e-152 507.7 40.5 2.9e-152 507.5 28.1 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.11 EME26816.1 - 8.6e-15 54.1 33.1 1.6e-14 53.2 22.9 1.4 1 1 0 1 1 1 1 Citrate transporter DUF4134 PF13572.1 EME26816.1 - 0.065 13.3 0.2 0.065 13.3 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4134) Asparaginase PF00710.15 EME26816.1 - 0.087 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Asparaginase SNF2_N PF00176.18 EME26817.1 - 3.6e-74 249.2 0.0 3.6e-74 249.2 0.0 2.8 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME26817.1 - 2.1e-17 62.7 0.1 6.6e-17 61.1 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME26817.1 - 4.6e-09 35.5 0.0 1.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EME26817.1 - 1e-06 28.7 3.4 2.3e-06 27.5 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.8 EME26817.1 - 0.0055 16.4 7.6 0.018 14.8 5.3 2.0 1 0 0 1 1 1 1 HSA Abhydrolase_6 PF12697.2 EME26818.1 - 5.7e-38 131.0 0.0 6.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME26818.1 - 5.4e-12 45.6 0.0 2.4e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME26818.1 - 2.4e-10 40.3 0.0 4.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME26818.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EME26818.1 - 3.2e-05 23.4 0.0 6.4e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EME26818.1 - 5.7e-05 22.7 0.0 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.11 EME26818.1 - 0.00019 20.9 0.0 0.081 12.3 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1057 PF06342.7 EME26818.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PUB PF09409.5 EME26818.1 - 0.053 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 PUB domain G10 PF01125.12 EME26819.1 - 4e-47 159.4 0.5 4e-47 159.4 0.3 1.7 2 0 0 2 2 2 1 G10 protein Transcrip_act PF04949.8 EME26820.1 - 0.039 13.5 0.6 0.039 13.5 0.4 1.7 2 0 0 2 2 2 0 Transcriptional activator R3H-assoc PF13902.1 EME26820.1 - 0.051 13.5 0.3 0.051 13.5 0.2 2.1 1 1 0 2 2 2 0 R3H-associated N-terminal domain DUF3870 PF12986.2 EME26820.1 - 1.4 9.2 6.4 0.55 10.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) Bystin PF05291.6 EME26822.1 - 1.3e-104 349.3 2.6 1.9e-104 348.8 1.8 1.2 1 0 0 1 1 1 1 Bystin HEAT_2 PF13646.1 EME26823.1 - 8.9e-24 83.5 2.3 7.4e-14 51.8 0.0 2.5 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EME26823.1 - 4.8e-10 38.6 0.3 0.12 12.4 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat HEAT_PBS PF03130.11 EME26823.1 - 1e-09 37.9 0.3 0.014 15.8 0.1 5.0 5 0 0 5 5 5 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EME26823.1 - 8.1e-06 26.1 5.1 0.018 15.5 0.0 4.4 3 2 2 5 5 5 2 HEAT-like repeat DGF-1_4 PF11024.3 EME26824.1 - 0.043 14.2 1.5 0.043 14.2 1.0 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 DUF3411 PF11891.3 EME26825.1 - 1e-41 142.6 0.0 3.1e-41 141.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3411) ATP_bind_1 PF03029.12 EME26826.1 - 7e-67 225.4 0.1 8e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EME26826.1 - 1.5e-05 24.4 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 EME26826.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME26826.1 - 0.00086 20.1 0.0 0.0016 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME26826.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EME26826.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EME26826.1 - 0.026 13.6 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 EME26826.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EME26826.1 - 0.057 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MipZ PF09140.6 EME26826.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ PduV-EutP PF10662.4 EME26826.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EME26826.1 - 0.2 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 ArgK protein ATP_bind_1 PF03029.12 EME26827.1 - 7e-67 225.4 0.1 8e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EME26827.1 - 1.5e-05 24.4 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 EME26827.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME26827.1 - 0.00086 20.1 0.0 0.0016 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME26827.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EME26827.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EME26827.1 - 0.026 13.6 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 EME26827.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EME26827.1 - 0.057 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MipZ PF09140.6 EME26827.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ PduV-EutP PF10662.4 EME26827.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EME26827.1 - 0.2 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 ArgK protein Phosphoesterase PF04185.9 EME26828.1 - 3.5e-25 88.9 2.1 2.1e-15 56.8 0.1 2.1 2 0 0 2 2 2 2 Phosphoesterase family DUF1654 PF07867.6 EME26829.1 - 0.17 11.2 0.0 0.47 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME26830.1 - 0.0041 16.8 0.8 0.083 12.5 0.0 2.9 3 1 0 3 3 3 1 Archaeal ATPase Transketolase_N PF00456.16 EME26831.1 - 2.7e-68 230.2 0.2 3.7e-68 229.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EME26831.1 - 2.3e-39 134.7 0.4 4e-39 133.9 0.3 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME26831.1 - 9.3e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF1077 PF06417.7 EME26832.1 - 4.5e-17 61.5 0.6 5.9e-17 61.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Alpha_E3_glycop PF01563.11 EME26833.1 - 0.075 12.8 0.7 9.9 6.0 0.0 3.2 3 0 0 3 3 3 0 Alphavirus E3 glycoprotein BAR PF03114.13 EME26834.1 - 0.0016 18.0 9.9 0.0031 17.0 6.8 1.4 1 1 0 1 1 1 1 BAR domain DUF745 PF05335.8 EME26834.1 - 0.034 13.6 5.0 0.069 12.6 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF1789 PF08748.6 EME26834.1 - 0.34 11.0 3.7 0.42 10.7 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) FliD_N PF02465.13 EME26834.1 - 1.6 9.1 5.2 34 4.8 0.1 3.3 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1090 PF06476.7 EME26834.1 - 2.6 7.7 11.0 5.1 6.7 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) DUF883 PF05957.8 EME26834.1 - 7.3 7.0 8.5 9.7 6.6 1.7 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) 6PF2K PF01591.13 EME26835.1 - 3.1e-78 261.8 0.1 4.2e-78 261.4 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EME26835.1 - 4.1e-33 114.7 0.4 1e-32 113.4 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EME26835.1 - 6.6e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME26835.1 - 0.00039 21.2 0.1 0.0015 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME26835.1 - 0.017 14.2 0.0 0.074 12.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 EME26835.1 - 0.038 13.1 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF1631 PF07793.6 EME26835.1 - 0.14 10.2 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Na_H_Exchanger PF00999.16 EME26836.1 - 1e-37 129.6 42.7 1.4e-37 129.1 29.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.24 EME26836.1 - 4.9e-06 26.2 0.0 1.4e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CC PF04942.9 EME26836.1 - 2.9 7.8 4.8 0.53 10.2 0.7 1.7 2 0 0 2 2 2 0 CC domain Glyco_transf_92 PF01697.22 EME26837.1 - 3.9e-26 92.0 1.1 4.9e-26 91.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EME26837.1 - 1.1e-11 44.8 0.3 2e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PBP PF01161.15 EME26839.1 - 5.8e-39 133.2 0.1 6.5e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Inositol_P PF00459.20 EME26840.1 - 6.5e-71 238.8 0.0 7.5e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.27 EME26841.1 - 8.3e-57 187.1 35.6 9.8e-11 41.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME26841.1 - 0.032 12.5 0.0 0.73 8.0 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Chromo PF00385.19 EME26842.1 - 5.2e-13 48.4 0.1 1.5e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Bromodomain PF00439.20 EME26842.1 - 7.5e-08 32.1 0.0 2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain MBT PF02820.13 EME26842.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 mbt repeat Tudor-knot PF11717.3 EME26842.1 - 0.066 12.9 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-CCHC PF00098.18 EME26843.1 - 9e-19 66.4 36.0 1.4e-05 24.7 1.0 5.7 6 0 0 6 6 6 5 Zinc knuckle Elf1 PF05129.8 EME26843.1 - 0.02 14.5 3.5 0.02 14.5 2.4 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-CCHC_4 PF14392.1 EME26843.1 - 0.056 13.1 36.9 1 9.0 0.9 5.5 4 1 1 5 5 5 0 Zinc knuckle BatD PF13584.1 EME26844.1 - 0.0056 15.3 0.0 0.0075 14.9 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF2370 PF10176.4 EME26844.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4305 PF14146.1 EME26844.1 - 2.1 8.1 4.2 23 4.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) DUF563 PF04577.9 EME26845.1 - 1.9e-09 37.7 0.2 2.1e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF563) Peptidase_M3_N PF08439.5 EME26845.1 - 0.021 14.8 0.5 0.059 13.4 0.3 1.8 1 1 0 1 1 1 0 Oligopeptidase F FAD_binding_3 PF01494.14 EME26846.1 - 7.8e-16 58.0 3.2 4e-14 52.4 2.2 2.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EME26846.1 - 1.2e-07 31.0 0.4 0.037 12.9 0.1 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein Trp_halogenase PF04820.9 EME26846.1 - 3.8e-05 22.5 0.1 0.0078 14.8 0.0 2.9 2 1 0 2 2 2 1 Tryptophan halogenase SE PF08491.5 EME26846.1 - 0.0018 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.17 EME26846.1 - 0.0029 16.5 0.2 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.1 EME26846.1 - 0.017 14.0 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME26846.1 - 0.028 14.1 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EME26846.1 - 0.038 12.8 0.1 0.65 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fringe PF02434.11 EME26847.1 - 2.6e-13 49.8 0.0 5.1e-12 45.5 0.0 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EME26847.1 - 0.00057 19.1 0.0 0.00091 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.16 EME26847.1 - 0.0016 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase MotB_plug PF13677.1 EME26847.1 - 0.086 12.1 0.0 0.26 10.6 0.0 1.8 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF1980 PF09323.5 EME26847.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AA_kinase PF00696.23 EME26848.1 - 6.3e-35 120.8 0.3 9.1e-35 120.3 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EME26848.1 - 2.8e-20 71.8 0.2 8.3e-20 70.2 0.0 2.0 2 0 0 2 2 2 1 PUA domain Stn1 PF10451.4 EME26849.1 - 7.6e-05 21.6 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 DUF4539 PF15072.1 EME26849.1 - 0.066 12.9 0.3 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF202 PF02656.10 EME26850.1 - 1.3e-08 34.9 1.5 1.3e-08 34.9 1.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF202) FA_desaturase PF00487.19 EME26850.1 - 0.28 10.5 6.7 0.033 13.6 1.7 1.5 1 1 1 2 2 2 0 Fatty acid desaturase DUF2367 PF10164.4 EME26850.1 - 1.3 8.9 5.3 1.7 8.5 0.5 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF4306 PF14154.1 EME26850.1 - 1.7 8.6 5.4 1.7 8.6 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4306) zf-DHHC PF01529.15 EME26850.1 - 4.4 6.6 6.6 1.3 8.4 2.6 1.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Oxidored_molyb PF00174.14 EME26851.1 - 5.9e-54 182.0 0.0 8.3e-54 181.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EME26851.1 - 1.4e-33 115.3 0.0 2.2e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SufE PF02657.10 EME26852.1 - 3.5e-29 100.9 0.0 5.3e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.13 EME26852.1 - 2.7e-27 94.5 0.2 4.8e-27 93.7 0.2 1.4 1 0 0 1 1 1 1 BolA-like protein Myb_DNA-binding PF00249.26 EME26853.1 - 3.2e-12 46.2 0.2 2.8e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME26853.1 - 7.1e-06 26.0 2.3 0.017 15.2 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain CCT PF06203.9 EME26854.1 - 9.8e-18 63.5 12.4 2.3e-17 62.3 8.6 1.6 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.19 EME26854.1 - 0.011 15.5 10.2 0.011 15.5 7.1 2.3 2 0 0 2 2 2 0 B-box zinc finger FAD_binding_3 PF01494.14 EME26855.1 - 4.4e-27 95.0 0.0 1.7e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME26855.1 - 3.6e-07 29.3 0.4 5.8e-07 28.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME26855.1 - 6.9e-07 29.2 0.3 1.5e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME26855.1 - 4.7e-06 25.7 0.6 9.2e-06 24.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EME26855.1 - 0.00061 18.7 0.1 0.00083 18.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EME26855.1 - 0.00073 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME26855.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME26855.1 - 0.0049 15.3 0.1 0.0074 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EME26855.1 - 0.0063 15.6 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME26855.1 - 0.011 14.8 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME26855.1 - 0.031 13.2 0.1 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.5 EME26855.1 - 0.08 11.7 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EME26855.1 - 0.11 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EME26855.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME26855.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME26856.1 - 4.4e-27 95.0 0.0 1.7e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME26856.1 - 3.6e-07 29.3 0.4 5.8e-07 28.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME26856.1 - 6.9e-07 29.2 0.3 1.5e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME26856.1 - 4.7e-06 25.7 0.6 9.2e-06 24.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EME26856.1 - 0.00061 18.7 0.1 0.00083 18.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EME26856.1 - 0.00073 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME26856.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME26856.1 - 0.0049 15.3 0.1 0.0074 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EME26856.1 - 0.0063 15.6 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME26856.1 - 0.011 14.8 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME26856.1 - 0.031 13.2 0.1 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.5 EME26856.1 - 0.08 11.7 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EME26856.1 - 0.11 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EME26856.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME26856.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Abhydrolase_2 PF02230.11 EME26857.1 - 7.9e-43 146.4 0.0 9.4e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME26857.1 - 5.8e-11 42.3 0.0 8.2e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME26857.1 - 5.5e-07 29.6 0.0 8.9e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EME26857.1 - 1.5e-06 27.7 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EME26857.1 - 9.7e-06 24.9 0.0 0.012 14.8 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family DUF829 PF05705.9 EME26857.1 - 0.0028 17.3 0.0 0.0086 15.7 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.13 EME26857.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF676 PF05057.9 EME26857.1 - 0.094 11.9 0.0 1.2 8.3 0.0 2.1 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Tetraspannin PF00335.15 EME26858.1 - 5.6e-19 68.3 21.3 6.6e-19 68.0 14.7 1.0 1 0 0 1 1 1 1 Tetraspanin family IncA PF04156.9 EME26858.1 - 0.027 14.0 0.9 0.027 14.0 0.6 2.5 3 0 0 3 3 3 0 IncA protein DUF2207 PF09972.4 EME26858.1 - 0.61 8.5 3.3 0.82 8.1 2.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 EME26858.1 - 5 7.2 10.6 1.5 8.9 2.2 2.5 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Pkinase PF00069.20 EME26860.1 - 4.9e-54 183.2 0.0 7.8e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26860.1 - 7.9e-40 136.5 0.0 1.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME26860.1 - 5.5e-06 25.5 0.0 1.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like HALZ PF02183.13 EME26860.1 - 4.5 7.0 9.7 1.1 9.0 3.7 2.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ribosom_S12_S23 PF00164.20 EME26861.1 - 2.4e-50 169.0 3.2 2.8e-50 168.8 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 eIF-1a PF01176.14 EME26861.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 RNA_pol_Rbc25 PF08292.7 EME26862.1 - 9.4e-30 103.3 2.8 2.9e-29 101.7 2.0 1.7 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EME26862.1 - 4.2e-12 46.0 0.0 8.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EME26863.1 - 6.6e-25 87.6 0.3 1.1e-24 86.9 0.2 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EME26863.1 - 3.9e-12 46.1 0.0 8.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Adenylsucc_synt PF00709.16 EME26864.1 - 6.3e-164 545.6 0.0 7.1e-164 545.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3134 PF11332.3 EME26866.1 - 1.6e-05 24.9 0.4 2.8e-05 24.1 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3134) CtaG_Cox11 PF04442.9 EME26867.1 - 0.029 14.1 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 WD40 PF00400.27 EME26868.1 - 2.6e-22 77.8 13.0 3.4e-07 29.9 0.3 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EME26868.1 - 0.03 14.0 0.0 0.52 10.1 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Spc7 PF08317.6 EME26869.1 - 1.2e-13 50.4 17.6 1.2e-13 50.4 12.2 2.8 3 0 0 3 3 3 1 Spc7 kinetochore protein RINGv PF12906.2 EME26870.1 - 2e-11 43.7 5.9 2e-11 43.7 4.1 1.8 2 0 0 2 2 2 1 RING-variant domain DUF3094 PF11293.3 EME26870.1 - 0.087 12.2 0.4 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) FANCL_C PF11793.3 EME26870.1 - 0.14 12.1 5.1 0.045 13.7 1.4 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 EME26870.1 - 2.3 8.1 11.6 7.7 6.4 8.2 1.9 1 1 1 2 2 2 0 Ring finger domain TBCC PF07986.7 EME26871.1 - 3.1e-24 84.6 1.5 1.2e-23 82.8 1.1 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.6 EME26871.1 - 0.0052 16.1 2.0 0.0093 15.3 1.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Glycos_transf_1 PF00534.15 EME26872.1 - 7.6e-13 48.2 0.0 7.2e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME26872.1 - 5.4e-05 23.3 0.0 0.00014 21.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME26872.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 UPF0154 PF03672.8 EME26872.1 - 0.014 14.9 3.7 0.075 12.6 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF846 PF05832.7 EME26874.1 - 4.3e-55 185.3 11.3 5.4e-55 185.0 7.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 EME26874.1 - 0.0092 15.9 8.7 0.13 12.2 0.1 2.1 2 0 0 2 2 2 2 Tic20-like protein DUF4191 PF13829.1 EME26874.1 - 0.017 14.2 1.9 2.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HXXEE PF13787.1 EME26874.1 - 0.029 14.7 4.0 0.75 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF3487 PF11990.3 EME26874.1 - 6.6 6.1 9.7 1.1 8.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Coatomer_WDAD PF04053.9 EME26875.1 - 3.6e-147 490.7 0.0 4.1e-146 487.2 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EME26875.1 - 1.3e-50 167.5 0.0 9.9e-10 37.9 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME26875.1 - 0.001 17.2 0.0 0.15 10.1 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EME26875.1 - 0.0041 16.8 0.0 5.9 6.7 0.0 4.2 5 2 2 7 7 7 2 Ciliary BBSome complex subunit 2, middle region SecY PF00344.15 EME26876.1 - 8.4e-94 314.3 16.0 1.1e-93 313.9 11.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EME26876.1 - 1.6e-16 59.5 1.6 1.8e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p IncA PF04156.9 EME26877.1 - 0.15 11.5 9.4 0.14 11.7 1.0 2.2 1 1 1 2 2 2 0 IncA protein AATF-Che1 PF13339.1 EME26877.1 - 1.9 8.6 7.1 8.7 6.5 0.2 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Pkinase PF00069.20 EME26878.1 - 5.8e-50 169.8 0.1 1e-49 169.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME26878.1 - 6e-34 117.2 0.1 1e-33 116.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EME26878.1 - 5.1e-16 58.7 0.0 1.4e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME26878.1 - 1e-14 54.5 0.0 3.2e-08 33.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EME26878.1 - 4.7e-12 45.0 0.0 1.2e-08 34.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EME26878.1 - 1.7e-09 37.6 0.0 4.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME26878.1 - 6.4e-07 29.0 0.0 2.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Kdo PF06293.9 EME26878.1 - 0.00043 19.4 0.1 0.00043 19.4 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family OSR1_C PF12202.3 EME26878.1 - 0.021 14.4 0.1 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal MRP-S26 PF14943.1 EME26879.1 - 0.0004 19.9 0.3 0.00085 18.9 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 CytochromB561_N PF09786.4 EME26880.1 - 7.5e-09 34.5 0.2 7.5e-09 34.5 0.1 1.5 2 0 0 2 2 2 1 Cytochrome B561, N terminal Alpha-amylase PF00128.19 EME26881.1 - 1.2e-25 90.6 0.0 3.5e-25 89.0 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Cu_amine_oxid PF01179.15 EME26882.1 - 2.6e-64 217.4 0.0 3.6e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EME26882.1 - 1e-18 67.2 0.0 2.4e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EME26882.1 - 1.4e-11 44.2 0.0 3.9e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain AA_permease PF00324.16 EME26883.1 - 2.5e-29 101.9 42.7 3e-27 95.1 29.6 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME26883.1 - 1.3e-27 96.4 47.6 1.6e-26 92.8 33.3 1.8 1 1 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 EME26886.1 - 5.8e-156 519.4 0.0 6.5e-156 519.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME26886.1 - 0.025 13.8 0.0 0.093 11.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) PAD_porph PF04371.10 EME26887.1 - 8.7e-124 412.8 0.0 1.1e-123 412.5 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 EME26887.1 - 0.0015 17.7 0.0 0.096 11.7 0.0 2.4 2 0 0 2 2 2 2 Amidinotransferase Aldedh PF00171.17 EME26890.1 - 8.8e-34 116.6 0.0 9.8e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME26890.1 - 0.00034 19.9 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Aldedh PF00171.17 EME26891.1 - 8.8e-34 116.6 0.0 9.8e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME26891.1 - 0.00034 19.9 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Aldedh PF00171.17 EME26892.1 - 8.6e-13 47.4 1.2 1.8e-10 39.8 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_7 PF03441.9 EME26893.1 - 1.7e-37 129.1 2.5 8.2e-37 126.9 0.3 2.7 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME26893.1 - 1.3e-20 73.8 1.1 2.5e-20 72.8 0.8 1.5 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EME26894.1 - 1.2e-39 136.1 4.2 3.3e-39 134.7 0.8 2.7 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME26894.1 - 1.2e-20 73.9 1.1 2.3e-20 72.9 0.8 1.5 1 0 0 1 1 1 1 DNA photolyase bZIP_1 PF00170.16 EME26895.1 - 7e-06 25.9 10.8 7e-06 25.9 7.5 1.9 2 0 0 2 2 2 1 bZIP transcription factor HALZ PF02183.13 EME26895.1 - 0.058 13.1 1.5 0.16 11.6 1.0 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper SEEEED PF14797.1 EME26895.1 - 0.31 11.2 5.0 0.66 10.1 3.5 1.5 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex bZIP_Maf PF03131.12 EME26895.1 - 5.6 7.3 17.6 0.068 13.4 5.1 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor LRR_6 PF13516.1 EME26896.1 - 1.6e-17 61.5 21.4 0.063 13.3 0.0 10.1 9 1 1 10 10 10 6 Leucine Rich repeat LRR_8 PF13855.1 EME26896.1 - 1.9e-08 33.9 13.0 0.014 15.1 0.1 5.0 3 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EME26896.1 - 1.1e-07 31.2 17.7 0.068 12.8 0.2 6.0 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EME26896.1 - 5.5e-06 25.6 12.1 4.4 7.7 0.0 7.7 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 EME26896.1 - 5.9e-05 22.6 8.5 3.3 8.3 0.1 7.2 6 0 0 6 6 6 1 Leucine rich repeat Cyclin_N PF00134.18 EME26897.1 - 2.6e-20 72.2 0.3 1.9e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME26897.1 - 8.4e-05 22.4 0.7 0.00018 21.4 0.2 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain ADH_zinc_N PF00107.21 EME26898.1 - 4.1e-22 78.1 0.5 6.6e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Amidase PF01425.16 EME26900.1 - 8.4e-68 229.2 0.0 2.9e-67 227.4 0.0 1.7 1 1 0 1 1 1 1 Amidase Med14 PF08638.6 EME26901.1 - 1.7e-13 50.2 0.0 3.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Med14 PF08638.6 EME26902.1 - 1.5e-13 50.4 0.0 3.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 WD40 PF00400.27 EME26903.1 - 4.6e-09 35.8 7.4 7.4e-06 25.6 0.3 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat CPSF_A PF03178.10 EME26903.1 - 0.013 14.5 0.2 0.043 12.9 0.1 1.9 2 1 1 3 3 3 0 CPSF A subunit region PRA1 PF03208.14 EME26904.1 - 2.9e-22 78.6 8.8 4.6e-22 78.0 6.1 1.2 1 0 0 1 1 1 1 PRA1 family protein Pho86 PF11124.3 EME26904.1 - 0.085 11.8 1.6 0.12 11.3 1.1 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Ndc1_Nup PF09531.5 EME26904.1 - 5.5 5.2 8.6 7.8 4.7 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ACT PF01842.20 EME26906.1 - 3.8e-09 35.8 0.0 0.00064 19.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.1 EME26906.1 - 0.0096 15.6 0.1 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 EME26906.1 - 0.01 16.1 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 0 ACT domain Reticulon PF02453.12 EME26907.1 - 1.5e-25 89.7 11.9 1.9e-25 89.4 8.2 1.1 1 0 0 1 1 1 1 Reticulon Peptidase_M50B PF13398.1 EME26907.1 - 0.26 10.6 9.4 0.065 12.6 2.6 2.1 2 0 0 2 2 2 0 Peptidase M50B-like UBX PF00789.15 EME26908.1 - 8.9e-11 41.7 0.0 2.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EME26908.1 - 2.1e-08 33.5 0.0 4.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EME26908.1 - 0.025 14.5 0.1 0.088 12.8 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin-like PXA PF02194.10 EME26908.1 - 0.031 13.8 5.3 0.062 12.8 3.7 1.5 1 0 0 1 1 1 0 PXA domain Lumazine_bd PF12870.2 EME26908.1 - 0.23 11.5 1.3 0.58 10.2 0.9 1.7 1 0 0 1 1 1 0 Lumazine-binding domain Selenoprotein_S PF06936.6 EME26908.1 - 7.2 6.1 13.1 15 5.0 9.1 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) Epimerase PF01370.16 EME26909.1 - 8e-48 162.9 0.0 1.2e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME26909.1 - 4.2e-12 45.3 0.0 5.6e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME26909.1 - 6.1e-09 36.1 0.0 1.3e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME26909.1 - 4.5e-08 32.3 0.0 0.0002 20.3 0.0 2.6 2 1 0 3 3 3 2 Male sterility protein Polysacc_synt_2 PF02719.10 EME26909.1 - 7.4e-08 31.6 0.0 5.4e-06 25.5 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME26909.1 - 1.3e-06 27.4 0.0 2.6e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EME26909.1 - 0.018 14.2 0.0 0.076 12.2 0.0 2.0 2 1 0 2 2 2 0 NmrA-like family adh_short PF00106.20 EME26909.1 - 0.02 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EME26909.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EME26909.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Orn_Arg_deC_N PF02784.11 EME26910.1 - 1.9e-69 233.6 0.0 2.5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME26910.1 - 1.5e-26 92.3 0.0 2.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EME26910.1 - 0.043 13.1 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TCR PF03638.10 EME26911.1 - 4e-28 96.9 49.9 2.5e-14 52.8 15.9 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF2346 PF09803.4 EME26912.1 - 5.5e-08 32.5 0.1 6.8e-08 32.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) CDI PF02234.14 EME26913.1 - 4.9e-09 35.8 1.5 1.4e-08 34.3 1.0 1.9 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor HARP PF07443.8 EME26913.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) HAND PF09110.6 EME26913.1 - 0.18 12.2 2.3 0.25 11.7 1.6 1.3 1 0 0 1 1 1 0 HAND WD40 PF00400.27 EME26914.1 - 2.9e-74 242.5 27.3 1.6e-13 49.9 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat LisH PF08513.6 EME26914.1 - 1.3e-10 40.6 0.6 2.2e-10 39.8 0.4 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EME26914.1 - 1e-08 35.1 0.0 0.011 15.4 0.0 4.2 1 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EME26914.1 - 4.5e-07 28.1 1.9 0.0012 16.8 0.1 3.1 2 1 0 2 2 2 2 IKI3 family Coatomer_WDAD PF04053.9 EME26914.1 - 6.2e-07 28.5 0.1 0.0024 16.7 0.0 3.1 3 1 0 3 3 3 2 Coatomer WD associated region Nup160 PF11715.3 EME26914.1 - 0.00031 19.0 2.1 0.74 7.8 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EME26914.1 - 0.0018 17.7 0.0 13 5.4 0.0 4.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 EME26914.1 - 0.039 13.6 4.6 0.27 10.9 0.1 3.3 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.6 EME26914.1 - 0.05 12.3 0.0 0.77 8.4 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.27 EME26915.1 - 4e-74 242.0 27.3 1.6e-13 49.9 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EME26915.1 - 1.2e-08 34.8 0.0 0.043 13.5 0.0 4.1 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EME26915.1 - 5.2e-07 27.9 1.9 0.0012 16.7 0.1 3.1 2 1 0 2 2 2 2 IKI3 family Coatomer_WDAD PF04053.9 EME26915.1 - 1.5e-06 27.2 0.0 0.0024 16.7 0.0 2.6 2 1 0 2 2 2 2 Coatomer WD associated region LisH PF08513.6 EME26915.1 - 2.2e-06 27.2 2.1 0.0052 16.5 0.1 2.4 2 0 0 2 2 2 2 LisH Nup160 PF11715.3 EME26915.1 - 0.00033 18.9 2.0 0.77 7.8 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EME26915.1 - 0.0021 17.4 0.0 13 5.3 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 EME26915.1 - 0.046 13.4 4.7 0.28 10.8 0.1 3.2 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.6 EME26915.1 - 0.056 12.1 0.0 0.94 8.1 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like GTP_EFTU PF00009.22 EME26916.1 - 5.2e-41 140.1 0.0 7.5e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME26916.1 - 1.8e-21 75.9 0.0 6.3e-20 70.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EME26916.1 - 4.5e-21 74.5 0.0 1.5e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME26916.1 - 6e-09 35.8 0.2 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EME26916.1 - 6e-08 32.4 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EME26916.1 - 4.3e-05 23.4 0.1 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME26916.1 - 8.2e-05 23.0 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EME26916.1 - 0.025 13.7 0.2 0.093 11.9 0.0 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EME26916.1 - 0.026 13.7 0.3 2.5 7.3 0.2 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EME26916.1 - 0.084 12.6 0.0 1 9.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family GBP PF02263.14 EME26916.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Prefoldin_2 PF01920.15 EME26917.1 - 0.015 15.0 1.2 0.015 15.0 0.9 2.5 2 1 0 2 2 2 0 Prefoldin subunit ALAD PF00490.16 EME26918.1 - 2.6e-139 463.6 0.0 3.1e-139 463.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Glycos_transf_1 PF00534.15 EME26919.1 - 1.1e-14 54.1 0.0 1.7e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME26919.1 - 9.2e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME26919.1 - 0.00013 22.1 0.0 0.00069 19.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycogen_syn PF05693.8 EME26919.1 - 0.034 12.4 0.0 0.046 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase NAPRTase PF04095.11 EME26920.1 - 2e-28 99.3 0.0 3.1e-26 92.1 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.11 EME26920.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain PPR_2 PF13041.1 EME26921.1 - 2.6e-50 168.1 14.5 3e-10 39.9 0.0 8.9 3 2 6 9 9 9 9 PPR repeat family PPR PF01535.15 EME26921.1 - 1.5e-26 90.4 12.5 0.0003 20.5 0.0 9.2 10 0 0 10 10 10 6 PPR repeat PPR_3 PF13812.1 EME26921.1 - 2.4e-26 89.7 6.2 0.0051 16.9 0.0 9.5 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME26921.1 - 6.5e-24 83.1 4.0 0.00044 19.6 0.0 8.8 10 0 0 10 10 10 4 PPR repeat ECSIT PF06239.6 EME26921.1 - 0.0079 15.0 1.0 21 3.9 0.0 4.4 2 1 3 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.15 EME26921.1 - 0.026 14.1 0.1 13 5.3 0.0 3.1 2 1 2 4 4 4 0 Region in Clathrin and VPS TPR_12 PF13424.1 EME26921.1 - 0.25 11.2 2.9 9.2 6.2 0.0 3.8 3 3 0 3 3 3 0 Tetratricopeptide repeat FBPase PF00316.15 EME26922.1 - 9.2e-118 392.7 0.1 1.1e-117 392.5 0.1 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EME26922.1 - 0.022 14.0 0.0 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 Inositol monophosphatase family Gtr1_RagA PF04670.7 EME26923.1 - 1.1e-55 188.3 0.1 1.4e-55 187.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EME26923.1 - 0.3 11.0 1.8 5.4 6.9 1.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain Rubredoxin PF00301.15 EME26924.1 - 2.9e-11 43.0 4.2 9.3e-11 41.4 2.2 2.2 2 0 0 2 2 2 1 Rubredoxin TF_Zn_Ribbon PF08271.7 EME26924.1 - 0.054 12.8 0.8 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Prim_Zn_Ribbon PF08273.7 EME26924.1 - 0.1 12.6 1.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.5 EME26924.1 - 0.17 11.3 0.8 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 EME26924.1 - 0.17 11.3 1.1 0.48 9.9 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EME26924.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EME26924.1 - 0.39 11.0 2.7 11 6.4 0.1 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.10 EME26924.1 - 2.8 7.5 6.5 1.3 8.6 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger MT-A70 PF05063.9 EME26927.1 - 1.1e-36 126.0 0.0 2.1e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 MT-A70 ZZ PF00569.12 EME26927.1 - 4.4e-32 109.3 39.0 1.1e-11 44.0 3.9 4.7 4 0 0 4 4 4 4 Zinc finger, ZZ type UQ_con PF00179.21 EME26928.1 - 1.9e-42 143.9 0.0 2.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME26928.1 - 0.00098 19.0 0.2 0.0018 18.1 0.2 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.6 EME26928.1 - 0.0051 16.2 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 EME26928.1 - 0.0062 16.2 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EME26928.1 - 0.0091 15.6 0.1 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain AHSA1 PF08327.6 EME26929.1 - 2.8e-16 59.7 0.2 1.5e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.6 EME26929.1 - 1e-13 51.2 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Ribosomal_S6 PF01250.12 EME26929.1 - 0.14 12.0 0.0 23 4.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S6 MM_CoA_mutase PF01642.17 EME26931.1 - 7.5e-235 779.9 0.1 1.1e-234 779.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 EME26931.1 - 1.6e-15 57.0 0.1 3.3e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain PhnI PF05861.7 EME26931.1 - 0.044 12.2 0.0 0.076 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Trypsin_2 PF13365.1 EME26933.1 - 2.4e-21 75.9 0.0 4e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EME26933.1 - 4.6e-14 52.5 0.0 8.8e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EME26933.1 - 6e-11 42.0 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.4 EME26933.1 - 0.024 13.0 0.9 0.041 12.2 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S29 PF02907.10 EME26933.1 - 0.041 13.4 0.1 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.1 EME26933.1 - 0.054 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain MIF4G PF02854.14 EME26934.1 - 3.9e-12 46.0 4.0 3.9e-12 46.0 2.8 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EME26934.1 - 1.5e-08 34.3 0.0 1.5e-08 34.3 0.0 2.8 4 1 1 5 5 5 1 MA3 domain PGI PF00342.14 EME26935.1 - 2.2e-188 626.6 0.0 2.7e-188 626.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase TBP PF00352.16 EME26936.1 - 1.7e-63 210.0 2.5 9.9e-32 108.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EME26936.1 - 9.5e-07 28.7 0.0 0.005 16.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) PAP2_C PF14360.1 EME26937.1 - 8.2e-17 61.2 5.7 8.2e-17 61.2 4.0 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 EME26937.1 - 1.2e-05 24.9 1.3 3.3e-05 23.4 0.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 EME26937.1 - 0.00021 20.9 3.9 0.00021 20.9 2.7 2.2 2 1 0 2 2 2 1 PAP2 superfamily zf-met PF12874.2 EME26938.1 - 4.9e-06 26.5 0.7 4.9e-06 26.5 0.5 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME26938.1 - 2.3e-05 24.3 0.5 4.7e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME26938.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EME26938.1 - 0.022 14.4 0.1 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 DBF zinc finger DUF4355 PF14265.1 EME26938.1 - 0.13 12.1 10.0 0.44 10.5 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) SPATIAL PF15256.1 EME26938.1 - 0.15 12.1 3.0 0.1 12.6 0.3 1.8 1 1 1 2 2 2 0 SPATIAL Sarcoglycan_2 PF05510.8 EME26938.1 - 0.22 9.8 2.6 0.3 9.3 1.7 1.5 1 1 0 1 1 1 0 Sarcoglycan alpha/epsilon Peptidase_S49_N PF08496.5 EME26938.1 - 4.9 6.9 10.0 0.24 11.2 2.5 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Iso_dh PF00180.15 EME26939.1 - 2.6e-98 329.1 0.0 3e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 EME26939.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Pex19 PF04614.7 EME26940.1 - 2e-28 99.6 20.0 7.6e-25 87.9 2.7 2.1 2 0 0 2 2 2 2 Pex19 protein family PGI PF00342.14 EME26940.1 - 0.016 13.6 0.2 0.027 12.8 0.1 1.4 1 1 1 2 2 2 0 Phosphoglucose isomerase ARL2_Bind_BART PF11527.3 EME26940.1 - 0.032 14.0 2.9 2.6 7.8 0.1 2.6 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART Fringe PF02434.11 EME26941.1 - 1.7e-10 40.5 0.0 5.6e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EME26941.1 - 3.8e-06 26.2 0.0 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.16 EME26941.1 - 0.00093 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase DUF2046 PF09755.4 EME26942.1 - 1.4e-37 129.2 52.7 1.9e-27 95.9 22.7 1.6 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Apolipoprotein PF01442.13 EME26942.1 - 0.001 18.6 19.4 0.001 18.6 13.4 2.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain DUF359 PF04019.7 EME26942.1 - 0.055 12.8 1.0 0.12 11.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF359) DUF3584 PF12128.3 EME26942.1 - 0.061 10.6 24.1 0.071 10.4 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MRF_C1 PF13887.1 EME26942.1 - 0.068 12.1 1.0 7.9 5.6 0.0 2.8 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Baculo_PEP_C PF04513.7 EME26942.1 - 0.29 10.9 12.7 0.45 10.3 2.9 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.7 EME26942.1 - 0.32 10.4 14.5 0.43 10.0 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Filament PF00038.16 EME26942.1 - 0.33 10.3 32.4 0.68 9.3 14.7 2.7 2 1 1 3 3 3 0 Intermediate filament protein DUF342 PF03961.8 EME26942.1 - 0.34 9.2 25.5 0.27 9.6 12.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3919 PF13057.1 EME26942.1 - 1.2 8.5 12.1 0.076 12.4 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) FlgN PF05130.7 EME26942.1 - 2.6 8.2 30.7 0.84 9.8 7.7 2.9 1 1 2 3 3 3 0 FlgN protein CorA PF01544.13 EME26942.1 - 3.3 6.6 16.3 4.9 6.0 10.7 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Borrelia_P83 PF05262.6 EME26942.1 - 4.2 5.5 20.3 5 5.2 14.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hexapep PF00132.19 EME26943.1 - 1.4e-13 49.6 14.3 4e-06 26.0 0.4 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME26943.1 - 7.7e-05 22.1 1.1 7.7e-05 22.1 0.7 3.9 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EME26943.1 - 0.4 9.1 3.7 5.3 5.5 0.1 2.2 1 1 1 2 2 2 0 L-fucokinase Myb_DNA-binding PF00249.26 EME26944.1 - 5.9e-08 32.6 0.4 5.9e-08 32.6 0.3 2.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain ZZ PF00569.12 EME26944.1 - 2.4e-06 26.9 6.2 4.8e-06 26.0 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EME26944.1 - 1.8e-05 24.7 0.4 8.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rsm1 PF08600.5 EME26944.1 - 0.074 12.9 0.2 0.26 11.1 0.1 2.0 1 0 0 1 1 1 0 Rsm1-like C1_3 PF07649.7 EME26944.1 - 5.4 7.1 13.5 12 5.9 9.3 1.7 1 0 0 1 1 1 0 C1-like domain PRP3 PF08572.5 EME26945.1 - 3.7e-59 199.8 10.3 3.7e-59 199.8 7.2 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EME26945.1 - 2.2e-34 117.8 0.2 2.2e-34 117.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) SIMPL PF04402.9 EME26945.1 - 0.015 15.1 0.9 0.015 15.1 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF541) Pox_P4B PF03292.9 EME26945.1 - 0.16 9.9 1.7 0.26 9.2 1.2 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein Aa_trans PF01490.13 EME26948.1 - 4.5e-26 91.2 24.9 5e-26 91.1 17.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAD_porph PF04371.10 EME26949.1 - 2e-06 27.1 0.0 2.2e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Aminotran_3 PF00202.16 EME26950.1 - 5.6e-88 295.0 0.0 7.4e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase_Tyr PF07714.12 EME26951.1 - 5.9e-57 192.6 0.0 9.4e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME26951.1 - 7.6e-56 189.1 0.0 1.6e-55 188.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TIR_2 PF13676.1 EME26951.1 - 0.03 14.4 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 TIR domain DUF167 PF02594.11 EME26952.1 - 1.8e-21 75.8 0.6 2.3e-21 75.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ACT_6 PF13740.1 EME26953.1 - 1.4e-17 63.1 0.0 1e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EME26953.1 - 3.8e-06 26.2 0.0 0.0021 17.5 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.1 EME26953.1 - 2.4e-05 24.5 0.0 0.0034 17.6 0.0 2.3 2 0 0 2 2 2 1 ACT domain KH_3 PF13014.1 EME26953.1 - 0.085 12.5 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 KH domain KH_1 PF00013.24 EME26953.1 - 0.11 12.1 0.0 9.9 5.8 0.0 2.5 2 0 0 2 2 2 0 KH domain GCD14_N PF14801.1 EME26955.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF2730 PF10805.3 EME26955.1 - 4.8 6.9 22.5 0.87 9.3 0.6 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) Citrate_synt PF00285.16 EME26956.1 - 3.4e-91 305.6 0.0 4.1e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Oxysterol_BP PF01237.13 EME26957.1 - 1.2e-42 145.7 3.0 4.3e-42 143.8 2.1 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein Ubie_methyltran PF01209.13 EME26957.1 - 2.5e-39 134.7 0.0 3.9e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EME26957.1 - 1.2e-16 60.9 0.0 2.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME26957.1 - 4.5e-14 52.9 0.0 8.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME26957.1 - 7.3e-14 51.6 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME26957.1 - 4.7e-10 39.7 0.0 1.4e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME26957.1 - 1.9e-08 34.7 0.0 4.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME26957.1 - 1.1e-07 31.7 0.1 2.8e-07 30.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26957.1 - 1.9e-06 27.8 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME26957.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EME26957.1 - 0.0032 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.14 EME26957.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family Methyltransf_4 PF02390.12 EME26957.1 - 0.02 13.9 0.0 0.053 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EME26957.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SprA-related PF12118.3 EME26957.1 - 6 6.1 6.2 0.33 10.2 0.6 1.5 2 0 0 2 2 2 0 SprA-related family PALP PF00291.20 EME26960.1 - 1.8e-46 158.8 0.1 2.4e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Chlor_dismutase PF06778.7 EME26960.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlorite dismutase HAD_2 PF13419.1 EME26962.1 - 4.2e-24 85.7 0.0 5.1e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME26962.1 - 8.8e-14 50.9 0.0 1.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME26962.1 - 1.7e-13 51.4 0.4 5.7e-12 46.4 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME26962.1 - 0.0032 17.6 0.0 0.0064 16.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EME26962.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.1 EME26962.1 - 0.074 12.9 0.0 7.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EME26962.1 - 0.082 12.5 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Acid Phosphatase XPG_N PF00752.12 EME26963.1 - 4e-23 81.6 0.0 1e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EME26963.1 - 7.5e-21 74.0 0.1 1.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EME26963.1 - 3.8e-05 23.3 0.0 7.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EME26963.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_11 PF13414.1 EME26963.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EME26963.1 - 0.016 15.0 0.0 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_G5 PF04599.7 EME26963.1 - 0.019 13.6 0.3 0.038 12.7 0.0 1.6 2 0 0 2 2 2 0 Poxvirus G5 protein TPR_1 PF00515.23 EME26963.1 - 0.029 13.9 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_2 PF12826.2 EME26963.1 - 0.083 12.7 0.0 0.54 10.1 0.0 2.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif DEAD PF00270.24 EME26964.1 - 4.6e-39 133.6 0.0 2.5e-38 131.2 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME26964.1 - 2.8e-20 71.9 0.0 6.1e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 EME26964.1 - 9.4e-09 35.1 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 EME26964.1 - 0.00012 22.0 0.0 0.00044 20.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PQQ_3 PF13570.1 EME26965.1 - 0.14 12.5 0.0 24 5.3 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain DNA_photolyase PF00875.13 EME26966.1 - 7.1e-23 81.1 0.1 1.5e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EME26966.1 - 4.2e-06 26.1 0.1 1.6e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase FBPase PF00316.15 EME26967.1 - 5e-119 396.9 0.0 6.4e-119 396.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EME26967.1 - 0.12 11.7 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Inositol monophosphatase family PPR_2 PF13041.1 EME26968.1 - 4.2e-60 199.5 13.4 7.8e-14 51.3 0.1 7.4 2 2 5 7 7 7 7 PPR repeat family PPR_1 PF12854.2 EME26968.1 - 3.7e-35 119.1 2.0 5.2e-09 35.4 0.0 7.7 9 0 0 9 9 9 5 PPR repeat PPR_3 PF13812.1 EME26968.1 - 5.7e-35 116.6 3.6 2.4e-05 24.2 0.0 8.4 8 0 0 8 8 8 6 Pentatricopeptide repeat domain PPR PF01535.15 EME26968.1 - 1.6e-34 115.4 17.3 5.6e-08 32.2 0.0 8.3 8 0 0 8 8 8 6 PPR repeat Apc3 PF12895.2 EME26968.1 - 2.5e-05 24.3 2.7 1.7 8.8 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 EME26968.1 - 0.003 17.1 1.5 2.9 7.4 0.0 3.3 2 1 2 4 4 4 2 Region in Clathrin and VPS DUF2095 PF09868.4 EME26968.1 - 0.0069 16.1 0.2 1 9.1 0.0 3.0 1 1 2 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2095) TPR_7 PF13176.1 EME26968.1 - 0.0073 16.0 0.2 0.34 10.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME26968.1 - 0.0099 15.8 1.6 0.57 10.1 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat F1F0-ATPsyn_F PF10791.4 EME26968.1 - 0.01 16.0 0.0 2.5 8.4 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi MNE1 PF13762.1 EME26968.1 - 0.012 15.7 0.2 0.12 12.4 0.1 2.6 1 1 0 2 2 2 0 Mitochondrial splicing apparatus component ECSIT PF06239.6 EME26968.1 - 0.018 13.9 0.1 2.5 6.8 0.0 3.6 2 1 3 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway Amidinotransf PF02274.12 EME26969.1 - 3.7e-20 72.1 0.0 5.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase zf-RING_2 PF13639.1 EME26969.1 - 1.2e-10 41.0 4.9 1.2e-10 41.0 3.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME26969.1 - 2.4e-06 27.5 3.5 6.1e-06 26.2 2.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME26969.1 - 1.1e-05 24.9 1.8 1.1e-05 24.9 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME26969.1 - 5.8e-05 23.0 6.5 0.00042 20.2 4.1 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME26969.1 - 0.00099 18.7 4.0 0.0029 17.2 2.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME26969.1 - 0.034 13.9 2.0 0.059 13.2 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EME26969.1 - 0.13 11.9 8.3 0.71 9.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MHYT PF03707.11 EME26969.1 - 0.36 10.9 2.9 0.79 9.8 2.0 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF2628 PF10947.3 EME26969.1 - 0.89 9.3 6.1 1.8 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Amidinotransf PF02274.12 EME26970.1 - 1.5e-20 73.4 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase zf-RING_2 PF13639.1 EME26970.1 - 1.2e-10 41.0 4.9 1.2e-10 41.0 3.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME26970.1 - 1.8e-06 27.9 3.5 6.1e-06 26.2 2.0 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME26970.1 - 1.1e-05 24.9 1.8 1.1e-05 24.9 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME26970.1 - 4.8e-05 23.2 6.4 0.00038 20.4 4.0 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME26970.1 - 0.0012 18.4 4.6 0.0046 16.6 3.2 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME26970.1 - 0.058 13.2 0.3 0.058 13.2 0.2 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EME26970.1 - 0.093 12.4 8.3 0.72 9.5 5.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MHYT PF03707.11 EME26970.1 - 0.36 10.9 2.9 0.78 9.8 2.0 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF2628 PF10947.3 EME26970.1 - 0.91 9.3 6.1 1.7 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) SNO PF01174.14 EME26971.1 - 1.6e-47 161.6 0.0 1.8e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EME26971.1 - 1.5e-07 31.1 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 EME26971.1 - 5.8e-06 26.1 0.0 6.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 EME26971.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 EME26971.1 - 0.018 14.2 0.0 0.039 13.2 0.0 1.5 2 0 0 2 2 2 0 Putative amidotransferase Peptidase_C26 PF07722.8 EME26971.1 - 0.05 13.0 0.6 0.17 11.3 0.4 2.0 1 1 0 1 1 1 0 Peptidase C26 DJ-1_PfpI PF01965.19 EME26971.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Oxidored_FMN PF00724.15 EME26972.1 - 3.8e-90 302.3 0.0 4.3e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C48 PF02902.14 EME26973.1 - 3e-28 98.9 3.0 3e-28 98.9 2.1 2.4 3 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 EME26973.1 - 0.0026 16.3 1.2 0.81 8.1 0.0 2.1 2 0 0 2 2 2 2 Vaccinia virus I7 processing peptidase G-patch PF01585.18 EME26974.1 - 1.2e-15 56.9 3.8 2.5e-15 55.9 2.7 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EME26974.1 - 4.6e-11 42.1 0.1 1.1e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME26974.1 - 8.2e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EME26974.1 - 1.2e-06 27.4 0.8 2.7e-06 26.3 0.6 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EME26974.1 - 1.2e-05 25.0 0.5 1.2e-05 25.0 0.3 2.4 3 0 0 3 3 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EME26974.1 - 0.00033 20.4 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Elong_Iki1 PF10483.4 EME26974.1 - 0.0041 16.5 3.3 0.0074 15.6 2.3 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 zf-met PF12874.2 EME26974.1 - 0.0083 16.3 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME26974.1 - 0.019 15.0 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 EME26974.1 - 0.039 13.7 2.3 0.097 12.5 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-DBF PF07535.7 EME26974.1 - 0.1 12.2 0.4 0.24 11.1 0.3 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_4 PF13894.1 EME26974.1 - 0.22 11.9 0.2 0.22 11.9 0.1 2.7 2 1 0 2 2 1 0 C2H2-type zinc finger PCI PF01399.22 EME26975.1 - 1.2e-21 76.9 2.0 1.2e-21 76.9 1.4 2.9 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EME26975.1 - 1.8e-12 47.1 0.7 4.3e-12 46.0 0.5 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EME26975.1 - 0.012 15.5 4.3 0.16 11.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME26975.1 - 0.013 15.4 0.3 9.2 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME26975.1 - 0.015 15.0 0.8 34 4.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cas_DxTHG PF09455.5 EME26975.1 - 1.7 7.6 12.7 0.5 9.4 2.5 2.4 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family PCI PF01399.22 EME26976.1 - 1.2e-21 76.9 2.0 1.2e-21 76.9 1.4 2.8 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EME26976.1 - 3.3e-12 46.3 0.8 8.2e-12 45.0 0.6 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EME26976.1 - 0.0061 16.4 3.7 0.16 11.9 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME26976.1 - 0.013 15.4 0.3 9.2 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME26976.1 - 0.015 15.0 0.8 34 4.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Prefoldin PF02996.12 EME26977.1 - 2.8e-29 101.2 0.2 7.4e-29 99.8 0.1 1.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EME26977.1 - 7.5e-05 22.4 0.5 0.00048 19.8 0.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit Rootletin PF15035.1 EME26977.1 - 0.0044 17.0 0.8 0.0069 16.3 0.6 1.3 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.16 EME26977.1 - 0.0078 15.7 0.6 0.06 12.8 0.1 2.0 2 0 0 2 2 2 1 Intermediate filament protein Fib_alpha PF08702.5 EME26977.1 - 0.074 13.1 1.2 0.78 9.8 0.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CCDC92 PF14916.1 EME26977.1 - 0.1 12.2 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Relaxase PF03432.9 EME26977.1 - 0.11 11.8 0.6 12 5.2 0.3 2.0 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Syntaxin-6_N PF09177.6 EME26977.1 - 0.5 10.7 3.3 25 5.3 0.1 2.8 1 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.13 EME26978.1 - 1e-64 218.4 0.6 1.6e-64 217.7 0.4 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EME26979.1 - 1.4e-60 204.7 0.1 2.1e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.27 EME26980.1 - 1.6e-34 116.5 11.6 2.4e-09 36.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME26980.1 - 0.0087 14.4 0.0 0.05 11.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EME26980.1 - 0.012 15.8 0.3 1.3 9.4 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Coatomer_WDAD PF04053.9 EME26980.1 - 0.02 13.6 0.0 1.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region SUKH_5 PF14567.1 EME26980.1 - 0.042 13.3 0.4 0.59 9.5 0.0 3.0 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall tRNA_anti-codon PF01336.20 EME26981.1 - 0.027 14.3 0.2 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Sigma70_r2 PF04542.9 EME26982.1 - 2.7e-18 65.3 0.1 7.7e-18 63.8 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EME26982.1 - 3.9e-15 54.8 0.4 2e-14 52.6 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.11 EME26982.1 - 7.2e-12 45.0 0.1 1.9e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-70 region 3 Glyco_transf_92 PF01697.22 EME26982.1 - 0.025 13.9 0.3 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 92 Aminotran_3 PF00202.16 EME26983.1 - 8.6e-84 281.2 0.0 1e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Metallophos PF00149.23 EME26984.1 - 7.2e-10 38.5 0.6 1.5e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 EME26984.1 - 3.6e-08 33.4 1.0 9.8e-08 32.0 0.7 1.7 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.2 EME26984.1 - 0.0014 18.5 0.0 0.0026 17.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cons_hypoth95 PF03602.10 EME26986.1 - 1.2e-34 119.2 0.0 1.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EME26986.1 - 3.2e-06 27.6 0.0 6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26986.1 - 4.3e-06 26.7 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME26986.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EME26986.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RsmJ PF04378.8 EME26986.1 - 0.052 12.5 0.0 0.13 11.1 0.0 1.8 2 1 0 2 2 2 0 Ribosomal RNA small subunit methyltransferase D, RsmJ MethyltransfD12 PF02086.10 EME26986.1 - 0.061 12.7 0.3 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.13 EME26986.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_PK PF05891.7 EME26986.1 - 0.18 11.1 0.0 1.5 8.1 0.0 1.9 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase zf-RING_2 PF13639.1 EME26987.1 - 1e-10 41.2 10.4 1e-10 41.2 7.2 2.0 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EME26987.1 - 1.3e-09 37.9 5.5 3.5e-09 36.6 3.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME26987.1 - 2.4e-07 30.2 8.8 6.9e-07 28.8 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME26987.1 - 6.3e-07 29.3 9.8 1.8e-06 27.8 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME26987.1 - 2.6e-05 23.7 9.7 5.6e-05 22.7 6.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME26987.1 - 9e-05 22.2 4.9 0.00018 21.2 3.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME26987.1 - 0.0013 18.4 8.0 0.0014 18.2 4.5 1.9 1 1 0 1 1 1 1 zinc-RING finger domain FtsL PF04999.8 EME26987.1 - 0.042 13.5 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL DUF1049 PF06305.6 EME26987.1 - 0.061 12.8 1.0 0.099 12.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3974 PF13120.1 EME26987.1 - 0.072 12.9 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) RINGv PF12906.2 EME26987.1 - 0.18 11.8 11.3 0.17 11.9 6.4 2.1 2 0 0 2 2 2 0 RING-variant domain HemY_N PF07219.8 EME26987.1 - 0.62 9.6 2.4 1.3 8.6 1.6 1.5 1 0 0 1 1 1 0 HemY protein N-terminus FANCL_C PF11793.3 EME26987.1 - 3.2 7.7 9.3 2.4 8.1 3.7 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain Phosphoesterase PF04185.9 EME26988.1 - 1e-24 87.4 3.9 1e-24 87.4 2.7 2.1 1 1 1 2 2 2 2 Phosphoesterase family EIF_2_alpha PF07541.7 EME26989.1 - 2.6e-36 123.7 0.0 8e-36 122.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EME26989.1 - 1.6e-12 47.3 0.2 1.6e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 S1 RNA binding domain Proteasome PF00227.21 EME26990.1 - 1.7e-50 170.9 0.1 2.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME26990.1 - 2.1e-15 55.6 0.1 3.3e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_A_bac PF01000.21 EME26990.1 - 0.03 14.4 0.3 0.05 13.7 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain FH2 PF02181.18 EME26991.1 - 8e-60 202.6 4.1 8e-60 202.6 2.8 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain GAS PF13851.1 EME26991.1 - 4.5 6.4 23.6 0.11 11.6 8.0 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EME26991.1 - 8.6 6.2 25.0 5.1 6.9 9.2 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding MutS_V PF00488.16 EME26992.1 - 8.7e-55 185.6 0.5 1.4e-54 185.0 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME26992.1 - 9.6e-24 84.2 0.0 5.6e-23 81.7 0.0 2.2 1 1 0 1 1 1 1 MutS domain III Arch_ATPase PF01637.13 EME26992.1 - 4.6e-05 23.2 0.0 0.00029 20.6 0.0 2.2 1 1 0 1 1 1 1 Archaeal ATPase MutS_IV PF05190.13 EME26992.1 - 0.0035 17.4 0.0 0.018 15.2 0.0 2.4 1 1 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EME26992.1 - 0.0048 16.7 1.1 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Fasciclin PF02469.17 EME26993.1 - 9.8e-15 54.6 1.2 1.3e-14 54.2 0.9 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF1514 PF07438.6 EME26993.1 - 0.025 14.4 0.7 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) FUR PF01475.14 EME26993.1 - 0.04 13.8 0.1 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family TrmB PF01978.14 EME26993.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.14 EME26993.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF992 PF06186.6 EME26993.1 - 0.061 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF992) Lum_binding PF00677.12 EME26993.1 - 0.46 10.4 4.9 0.97 9.3 2.9 1.9 1 1 1 2 2 2 0 Lumazine binding domain tRNA_U5-meth_tr PF05958.6 EME26994.1 - 2.4e-21 75.8 0.2 1.5e-20 73.2 0.1 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EME26994.1 - 4.8e-14 52.2 1.4 5.3e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME26994.1 - 2.1e-08 34.1 0.0 5.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME26994.1 - 7e-08 32.0 0.2 1.4e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EME26994.1 - 8.8e-08 31.9 0.1 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EME26994.1 - 2.8e-07 31.1 0.1 1.3e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME26994.1 - 5.4e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EME26994.1 - 9.6e-06 25.9 0.0 2.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME26994.1 - 0.00022 20.3 0.3 0.00044 19.3 0.2 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EME26994.1 - 0.00027 20.1 0.3 0.00061 19.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EME26994.1 - 0.00051 19.6 0.1 0.00093 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EME26994.1 - 0.00058 19.4 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 EME26994.1 - 0.0027 17.1 0.2 0.0054 16.1 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EME26994.1 - 0.0037 16.9 0.0 0.009 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME26994.1 - 0.0078 15.9 0.1 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EME26994.1 - 0.0091 15.5 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 DNA methylase Methyltransf_11 PF08241.7 EME26994.1 - 0.01 16.3 0.1 0.024 15.0 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EME26994.1 - 0.017 14.4 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EME26994.1 - 0.033 13.3 0.2 0.062 12.4 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME26994.1 - 0.035 14.5 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 EME26994.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.8 EME26994.1 - 0.061 12.6 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.15 EME26994.1 - 0.062 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_Mtase PF02384.11 EME26994.1 - 0.064 12.3 1.5 0.11 11.5 0.1 1.9 2 0 0 2 2 2 0 N-6 DNA Methylase NodS PF05401.6 EME26994.1 - 0.073 12.4 0.2 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) FtsJ PF01728.14 EME26994.1 - 0.074 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 EME26994.1 - 0.075 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 DREV methyltransferase RRM_6 PF14259.1 EME26994.1 - 0.096 12.6 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.18 EME26995.1 - 4.2e-41 141.2 4.8 1.9e-40 139.1 3.3 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME26995.1 - 1.9e-10 40.5 0.0 1.9e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EME26995.1 - 0.0047 16.7 0.5 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EME26995.1 - 0.015 15.7 0.7 0.78 10.2 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease TAXi_N PF14543.1 EME26995.1 - 0.11 12.4 17.3 0.047 13.6 9.6 2.2 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Asp_protease PF09668.5 EME26995.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease WD40 PF00400.27 EME26996.1 - 3.7e-15 55.1 4.3 1.6e-06 27.7 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME26996.1 - 0.056 11.7 0.0 0.18 10.0 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain CAP_C PF08603.6 EME26997.1 - 2.7e-49 166.5 7.6 4e-49 166.0 5.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.14 EME26997.1 - 3e-07 30.0 14.9 3e-07 30.0 10.3 2.1 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.7 EME26997.1 - 0.011 15.1 9.7 0.055 12.8 6.6 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor C DUF3244 PF11589.3 EME26997.1 - 0.78 9.4 4.7 0.91 9.2 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3244) Pex14_N PF04695.8 EME26997.1 - 7 6.7 14.0 8.1 6.4 0.9 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EME26998.1 - 0.036 13.8 1.8 0.11 12.2 1.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mer2 PF09074.5 EME26998.1 - 0.052 13.4 3.7 0.061 13.2 2.6 1.0 1 0 0 1 1 1 0 Mer2 DUF3450 PF11932.3 EME26998.1 - 0.06 12.6 3.0 0.082 12.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Serine_rich PF08824.5 EME26998.1 - 0.087 12.5 2.1 0.14 11.8 0.2 1.8 1 1 1 2 2 2 0 Serine rich protein interaction domain LOH1CR12 PF10158.4 EME26998.1 - 0.11 12.2 2.4 0.14 11.9 1.6 1.2 1 0 0 1 1 1 0 Tumour suppressor protein GHL5 PF14872.1 EME26998.1 - 0.13 10.0 1.0 0.13 9.9 0.7 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF464 PF04327.7 EME26998.1 - 0.14 12.3 1.9 0.41 10.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF464) Med8 PF10232.4 EME26998.1 - 0.16 11.4 4.0 0.25 10.8 2.6 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Fib_alpha PF08702.5 EME26998.1 - 0.21 11.7 1.7 0.34 11.0 1.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fringe PF02434.11 EME26998.1 - 0.26 10.4 2.7 1 8.5 0.2 2.0 1 1 0 2 2 2 0 Fringe-like Mnd1 PF03962.10 EME26998.1 - 0.46 10.1 4.6 0.58 9.7 3.2 1.1 1 0 0 1 1 1 0 Mnd1 family TBPIP PF07106.8 EME26998.1 - 1.3 8.5 7.0 1.8 8.0 4.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EME26998.1 - 2.1 7.9 13.6 5.4 6.5 9.4 1.6 1 1 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 EME26998.1 - 2.3 7.9 12.9 0.95 9.1 1.5 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Prefoldin_2 PF01920.15 EME26998.1 - 2.4 7.9 8.9 2.7 7.8 2.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit AAA_23 PF13476.1 EME26998.1 - 4.6 7.5 7.1 5.7 7.1 4.9 1.1 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 EME26999.1 - 8.8e-23 79.9 0.0 1.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME26999.1 - 6.7e-08 32.5 0.1 1.1e-06 28.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME26999.1 - 1.3e-07 31.7 0.1 3.2e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME26999.1 - 5.7e-07 29.4 0.1 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EME26999.1 - 6.5e-05 22.5 0.0 8.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME26999.1 - 0.0028 17.3 0.1 0.0045 16.6 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EME26999.1 - 0.016 14.7 0.1 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin MgtE PF01769.11 EME27000.1 - 4.2e-23 82.1 10.8 1.5e-22 80.3 5.4 2.1 2 0 0 2 2 2 1 Divalent cation transporter CBS PF00571.23 EME27000.1 - 1.5e-11 43.8 0.1 1.3e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain KOW PF00467.24 EME27001.1 - 1.2e-07 31.1 3.0 1.9e-07 30.5 0.8 2.1 2 0 0 2 2 2 1 KOW motif S10_plectin PF03501.10 EME27002.1 - 5.7e-39 131.8 0.0 6.7e-39 131.6 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain GATA PF00320.22 EME27003.1 - 4.1e-08 32.4 5.1 4.1e-08 32.4 3.5 2.2 3 0 0 3 3 3 1 GATA zinc finger Chloroplast_duf PF14476.1 EME27003.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Petal formation-expressed CCAP PF11105.3 EME27003.1 - 0.084 12.6 3.4 0.078 12.7 1.2 1.9 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a ATP-synt_C PF00137.16 EME27004.1 - 2.6e-33 113.7 33.3 2e-19 69.2 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.13 EME27004.1 - 0.55 10.0 3.5 1.1 9.0 2.4 1.4 1 0 0 1 1 1 0 Glycophorin A DUF4389 PF14333.1 EME27004.1 - 3.5 7.3 7.0 2.6 7.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Sec34 PF04136.10 EME27006.1 - 0.0036 17.0 5.2 0.031 13.9 0.4 2.4 1 1 1 2 2 2 1 Sec34-like family EAP30 PF04157.11 EME27006.1 - 0.024 13.8 0.9 0.024 13.8 0.6 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family MCPsignal PF00015.16 EME27006.1 - 0.094 12.2 1.2 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CENP-Q PF13094.1 EME27006.1 - 0.11 12.5 11.3 1.1 9.2 1.5 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 EME27006.1 - 0.12 11.5 0.7 0.2 10.7 0.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EME27006.1 - 0.17 11.7 13.0 0.66 9.8 2.6 2.4 2 0 0 2 2 2 0 Tropomyosin like CASP_C PF08172.7 EME27006.1 - 0.18 10.8 4.8 0.3 10.0 3.3 1.4 1 1 0 1 1 1 0 CASP C terminal PMC2NT PF08066.7 EME27006.1 - 0.77 10.0 3.9 7 7.0 0.3 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain IncA PF04156.9 EME27006.1 - 1.2 8.7 11.9 3.2 7.3 8.3 1.9 1 1 0 1 1 1 0 IncA protein PTRF_SDPR PF15237.1 EME27006.1 - 2.5 7.4 7.8 0.43 9.9 0.2 2.7 3 0 0 3 3 3 0 PTRF/SDPR family Carboxyl_trans PF01039.17 EME27007.1 - 1.6e-188 627.0 0.0 1.9e-188 626.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EME27007.1 - 0.0038 16.4 0.1 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) TPT PF03151.11 EME27008.1 - 1.6e-10 40.8 14.6 1.6e-10 40.8 10.1 3.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME27008.1 - 1.2e-08 35.0 32.4 0.00012 22.0 9.8 2.6 1 1 2 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EME27008.1 - 9.3e-05 22.6 30.3 0.00036 20.7 7.2 3.0 3 1 1 4 4 4 2 Multidrug resistance efflux transporter ATP_synt_I PF03899.10 EME27008.1 - 0.0074 16.4 0.4 0.0074 16.4 0.3 4.1 2 1 2 4 4 4 1 ATP synthase I chain UAA PF08449.6 EME27008.1 - 0.49 9.2 24.2 5.9 5.7 16.7 2.3 1 1 0 1 1 1 0 UAA transporter family ClpS PF02617.12 EME27009.1 - 2.1e-18 65.7 0.0 4.7e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF159 PF02586.9 EME27010.1 - 5e-47 160.1 0.0 6e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Ribosomal_S27e PF01667.12 EME27011.1 - 8.1e-28 95.7 6.2 9.8e-28 95.4 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EME27011.1 - 0.021 14.6 1.6 0.026 14.3 1.1 1.2 1 0 0 1 1 1 0 IBR domain zf-C2HC5 PF06221.8 EME27011.1 - 0.21 11.3 5.3 1.1 9.0 3.2 2.2 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF3133 PF11331.3 EME27011.1 - 1.1 8.9 4.6 2.3 7.8 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3133) ETC_C1_NDUFA5 PF04716.9 EME27012.1 - 2.6e-19 68.5 2.2 4.7e-19 67.6 1.5 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF1048 PF06304.6 EME27012.1 - 0.0038 17.5 0.2 0.0053 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) TRM PF02005.11 EME27013.1 - 4.9e-107 358.1 0.0 6.4e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf-IS66 PF13005.2 EME27013.1 - 0.043 13.7 1.5 2.2 8.3 0.3 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Met_10 PF02475.11 EME27013.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TRM PF02005.11 EME27014.1 - 2.7e-05 23.2 0.1 0.001 18.0 0.0 2.8 3 0 0 3 3 3 2 N2,N2-dimethylguanosine tRNA methyltransferase Beta-Casp PF10996.3 EME27015.1 - 6.6e-34 116.5 0.0 5.2e-32 110.4 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain CPSF73-100_C PF11718.3 EME27015.1 - 3.4e-29 101.7 0.1 5.3e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.22 EME27015.1 - 1.1e-19 70.9 0.0 1.5e-18 67.1 0.0 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME27015.1 - 2.5e-12 46.7 0.1 4.9e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EME27015.1 - 8.9e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EME27015.1 - 4e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pro_isomerase PF00160.16 EME27016.1 - 9.1e-43 146.1 0.0 2.2e-42 144.8 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1980 PF09323.5 EME27016.1 - 0.22 11.2 4.5 0.45 10.2 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4045 PF13254.1 EME27016.1 - 0.24 10.6 19.2 0.4 9.8 13.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4045) Pkinase PF00069.20 EME27017.1 - 9e-14 51.2 0.0 1.1e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27017.1 - 3.2e-10 39.5 0.0 3.7e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EME27017.1 - 7e-10 38.5 0.0 9e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EME27017.1 - 1.5e-09 37.2 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME27017.1 - 5.1e-07 29.6 0.0 0.00034 20.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 EME27017.1 - 0.0012 18.1 0.1 0.0015 17.7 0.1 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.6 EME27017.1 - 0.023 13.9 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1679 PF07914.6 EME27017.1 - 0.099 11.2 0.1 0.17 10.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Ribosomal_S24e PF01282.14 EME27018.1 - 9.6e-32 108.6 0.0 1.8e-31 107.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e UCH PF00443.24 EME27019.1 - 1.4e-47 162.1 0.4 2.4e-47 161.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME27019.1 - 3e-23 82.7 0.1 3.1e-22 79.3 0.1 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EME27019.1 - 3.1e-08 33.8 2.5 6.9e-05 23.1 0.3 2.8 2 1 0 2 2 2 2 DUSP domain AIF_C PF14721.1 EME27020.1 - 1.1e-06 28.9 0.7 4.9e-06 26.8 0.0 2.4 2 1 1 3 3 3 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.22 EME27020.1 - 4.6e-06 26.9 0.0 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME27020.1 - 0.021 14.7 0.0 9.7 6.0 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.21 EME27021.1 - 6e-39 132.6 0.1 6e-39 132.6 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME27021.1 - 0.0011 18.8 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 EME27021.1 - 0.079 12.4 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.8 EME27021.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain HMGL-like PF00682.14 EME27022.1 - 2e-58 197.8 0.0 2.4e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 HMGL-like HicB PF05534.7 EME27022.1 - 0.14 11.7 0.1 6.7 6.3 0.0 2.8 3 0 0 3 3 3 0 HicB family Rotamase PF00639.16 EME27023.1 - 6.8e-15 55.5 0.0 7.8e-08 32.9 0.0 2.9 3 0 0 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EME27023.1 - 1.2e-13 51.3 0.0 2.3e-12 47.1 0.0 2.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain UPF0240 PF06784.6 EME27023.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) TT_ORF2 PF02957.10 EME27023.1 - 0.06 14.0 1.3 1.9 9.1 0.0 2.3 1 1 1 2 2 2 0 TT viral ORF2 Rotamase_2 PF13145.1 EME27023.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rotamase PF00639.16 EME27024.1 - 2.7e-19 69.7 0.0 1.2e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EME27024.1 - 3.3e-17 62.8 0.0 7.7e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain UPF0240 PF06784.6 EME27024.1 - 9.5e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Rotamase_2 PF13145.1 EME27024.1 - 0.022 15.3 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain TT_ORF2 PF02957.10 EME27024.1 - 0.049 14.3 1.3 1.7 9.3 0.0 2.3 1 1 1 2 2 2 0 TT viral ORF2 Branch PF02485.16 EME27025.1 - 2.1e-30 105.7 1.7 3.4e-30 105.0 1.1 1.4 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Phosphorylase PF00343.15 EME27026.1 - 0 1057.8 0.0 0 1057.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Phosphorylase PF00343.15 EME27027.1 - 0 1057.9 0.0 0 1057.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CLTH PF10607.4 EME27028.1 - 1.4e-38 131.8 2.2 1.8e-38 131.5 1.5 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EME27028.1 - 1.4e-10 40.5 0.8 5.6e-10 38.6 0.1 2.3 2 0 0 2 2 2 1 LisH TPR_14 PF13428.1 EME27028.1 - 0.076 13.6 0.0 30 5.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SgrR_N PF12793.2 EME27028.1 - 1.3 9.0 4.0 7 6.6 0.1 3.2 3 1 1 4 4 4 0 Sugar transport-related sRNA regulator N-term HD_3 PF13023.1 EME27029.1 - 1.1e-41 142.3 0.2 1.3e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EME27029.1 - 2.2e-06 27.6 0.1 7.2e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 EME27029.1 - 0.046 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 HDOD domain CesA PF11439.3 EME27029.1 - 0.16 11.9 0.9 0.36 10.7 0.2 1.8 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA HD_3 PF13023.1 EME27030.1 - 1.7e-40 138.4 0.0 2.1e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EME27030.1 - 2.1e-06 27.7 0.1 6.7e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 HD domain HDOD PF08668.7 EME27030.1 - 0.048 12.9 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 HDOD domain Glutaredoxin PF00462.19 EME27031.1 - 8.4e-15 54.5 0.0 3e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EME27031.1 - 2.7e-06 27.0 0.0 6.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Epimerase PF01370.16 EME27031.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME27031.1 - 0.0052 15.7 0.0 0.014 14.3 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Thioredoxin_2 PF13098.1 EME27031.1 - 0.03 14.4 0.0 0.12 12.6 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2839 PF10999.3 EME27032.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2839) Pro_CA PF00484.14 EME27033.1 - 5.5e-29 101.1 0.0 7.1e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pex2_Pex12 PF04757.9 EME27034.1 - 7.4e-16 58.2 9.9 1e-15 57.8 6.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Pex2_Pex12 PF04757.9 EME27035.1 - 7.4e-16 58.2 9.9 1e-15 57.8 6.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region NAD_binding_1 PF00175.16 EME27036.1 - 1.2e-29 103.0 0.0 2.3e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME27036.1 - 1.4e-17 63.5 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EME27036.1 - 8.6e-06 25.7 0.0 0.00029 20.7 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Vault PF01505.13 EME27036.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Major Vault Protein repeat RWD PF05773.17 EME27037.1 - 1.1e-13 51.0 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain ILVD_EDD PF00920.16 EME27039.1 - 4.1e-198 659.0 0.5 4.7e-198 658.8 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family NOC3p PF07540.6 EME27040.1 - 1e-15 57.7 1.6 1.9e-15 56.9 0.5 1.9 2 0 0 2 2 2 1 Nucleolar complex-associated protein ApoO PF09769.4 EME27041.1 - 0.04 13.6 0.3 0.075 12.7 0.1 1.5 1 1 1 2 2 2 0 Apolipoprotein O V-set_CD47 PF08204.6 EME27041.1 - 0.045 13.5 0.4 0.062 13.0 0.3 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Streptin-Immun PF11083.3 EME27041.1 - 0.82 9.6 4.3 2.1 8.3 0.3 2.6 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein ApoO PF09769.4 EME27042.1 - 0.048 13.3 0.3 0.088 12.5 0.1 1.5 1 1 1 2 2 2 0 Apolipoprotein O V-set_CD47 PF08204.6 EME27042.1 - 0.053 13.2 0.4 0.074 12.8 0.3 1.1 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Streptin-Immun PF11083.3 EME27042.1 - 0.88 9.5 4.2 2.4 8.2 0.2 2.7 1 1 1 3 3 3 0 Lantibiotic streptin immunity protein UBX PF00789.15 EME27043.1 - 9e-18 64.1 0.1 2e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EME27043.1 - 2.7e-12 45.9 0.6 6.3e-12 44.8 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EME27043.1 - 5.1e-12 45.6 0.1 5.1e-12 45.6 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like OSR1_C PF12202.3 EME27043.1 - 0.077 12.6 0.5 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal DUF4266 PF14086.1 EME27043.1 - 0.31 11.5 1.5 20 5.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4266) ADH_N PF08240.7 EME27044.1 - 3.8e-27 94.2 1.4 3.8e-27 94.2 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME27044.1 - 4.6e-24 84.4 0.2 1.2e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME27044.1 - 2.1e-05 23.7 0.1 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EME27044.1 - 0.00052 19.7 0.2 0.0012 18.4 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME27044.1 - 0.00096 18.7 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EME27044.1 - 0.0016 17.9 0.2 0.0093 15.4 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EME27044.1 - 0.0035 17.3 0.1 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain GFO_IDH_MocA PF01408.17 EME27044.1 - 0.0036 17.8 0.0 0.015 15.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.10 EME27044.1 - 0.025 14.4 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 EME27044.1 - 0.027 15.0 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EME27044.1 - 0.03 14.8 0.1 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EME27044.1 - 0.034 13.2 0.0 0.07 12.1 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Pyr_redox PF00070.22 EME27044.1 - 0.047 14.0 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EME27044.1 - 0.048 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 EME27044.1 - 0.053 13.7 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_31 PF13847.1 EME27044.1 - 0.075 12.6 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain XdhC_C PF13478.1 EME27044.1 - 0.079 13.2 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 EME27044.1 - 0.18 11.6 0.6 0.66 9.7 0.2 2.1 2 0 0 2 2 2 0 ThiF family FimP PF09766.4 EME27045.1 - 7.2e-42 143.7 7.2 1.2e-24 87.0 5.1 3.5 3 1 1 4 4 4 2 Fms-interacting protein DUF86 PF01934.12 EME27045.1 - 0.024 14.2 1.1 0.92 9.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF86 NAD_binding_10 PF13460.1 EME27046.1 - 2.4e-25 89.6 0.0 7.2e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding CIA30 PF08547.7 EME27046.1 - 1e-15 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NmrA PF05368.8 EME27046.1 - 2.6e-11 43.2 0.2 1.3e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EME27046.1 - 9.2e-08 31.7 0.0 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME27046.1 - 4e-07 29.0 0.1 6e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EME27046.1 - 0.0025 17.7 0.1 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF4108 PF13390.1 EME27046.1 - 0.012 15.2 0.4 0.56 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) Clat_adaptor_s PF01217.15 EME27047.1 - 7.5e-39 132.6 0.8 8.5e-39 132.5 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_2 PF07719.12 EME27048.1 - 1.8e-27 92.9 4.0 0.0019 17.9 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EME27048.1 - 5.7e-27 93.1 3.3 1.9e-11 43.3 0.1 5.3 2 1 2 5 5 5 5 TPR repeat TPR_17 PF13431.1 EME27048.1 - 2.9e-23 80.0 0.0 0.0002 21.3 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME27048.1 - 1.2e-21 75.2 3.6 0.0032 17.9 0.2 8.7 4 1 6 10 10 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EME27048.1 - 2.5e-18 64.8 1.4 0.00049 19.5 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME27048.1 - 2.7e-17 61.1 1.3 0.1 12.4 0.0 7.9 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME27048.1 - 8.1e-17 61.3 0.0 9.7e-06 25.8 0.2 5.3 3 1 5 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EME27048.1 - 4e-16 57.4 4.6 0.034 13.9 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EME27048.1 - 2.8e-15 56.4 0.0 0.0022 18.5 0.1 5.9 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME27048.1 - 7.5e-15 54.6 3.4 3.6e-05 23.6 0.0 5.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 EME27048.1 - 2.9e-10 39.6 0.4 1.7e-05 24.0 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME27048.1 - 7e-08 32.4 2.3 15 6.2 0.0 7.3 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME27048.1 - 1.7e-06 27.7 0.5 0.0023 17.7 0.0 4.7 3 1 3 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 EME27048.1 - 9.5e-06 25.5 0.0 0.02 14.6 0.0 2.9 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) Apc3 PF12895.2 EME27048.1 - 5.7e-05 23.1 1.2 0.29 11.2 0.1 3.6 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.7 EME27048.1 - 0.00012 21.9 3.6 6 6.6 0.0 5.4 4 2 1 6 6 6 1 Mad3/BUB1 homology region 1 NARP1 PF12569.3 EME27048.1 - 0.00012 21.0 0.0 0.058 12.1 0.0 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 MIT PF04212.13 EME27048.1 - 0.0056 16.5 1.7 28 4.6 0.0 4.9 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Ank_2 PF12796.2 EME27048.1 - 0.0063 16.8 0.0 3.9 7.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) ChAPs PF09295.5 EME27048.1 - 0.06 12.0 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Xin PF08043.7 EME27048.1 - 0.16 11.7 0.3 13 5.7 0.0 3.9 4 0 0 4 4 4 0 Xin repeat PPR PF01535.15 EME27048.1 - 0.27 11.2 9.2 2e+02 2.2 0.0 6.6 7 1 1 8 8 7 0 PPR repeat Pet191_N PF10203.4 EME27049.1 - 1.9e-18 66.2 3.3 2.2e-18 66.0 2.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EME27049.1 - 5.8e-05 22.8 0.8 0.041 13.7 0.2 2.8 1 1 1 2 2 2 2 CHCH domain GCK PF07802.6 EME27049.1 - 0.099 12.7 2.7 1.6 8.9 0.2 2.3 1 1 1 2 2 2 0 GCK domain Cmc1 PF08583.5 EME27049.1 - 0.1 12.3 2.6 0.74 9.6 0.2 2.2 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Toxin_2 PF00451.14 EME27049.1 - 9.1 6.4 6.8 16 5.7 0.1 3.3 4 0 0 4 4 4 0 Scorpion short toxin, BmKK2 Methyltransf_26 PF13659.1 EME27050.1 - 1.5e-08 34.6 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME27050.1 - 5.7e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Spermine_synth PF01564.12 EME27050.1 - 0.00018 20.5 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EME27050.1 - 0.0002 21.9 0.0 0.00047 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.6 EME27050.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.1 EME27050.1 - 0.0028 17.2 0.0 0.0094 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME27050.1 - 0.0078 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 EME27050.1 - 0.027 13.5 0.0 0.049 12.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EME27050.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EME27050.1 - 0.056 12.5 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family E2F_TDP PF02319.15 EME27051.1 - 5.9e-24 83.4 0.6 1.7e-23 81.9 0.4 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EME27051.1 - 0.00048 19.7 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB N_Asn_amidohyd PF14736.1 EME27051.1 - 0.034 13.0 0.1 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase CENP-B_N PF04218.8 EME27051.1 - 0.037 13.4 0.1 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF349 PF03993.7 EME27051.1 - 0.06 13.5 2.9 0.13 12.4 2.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) RPA_C PF08784.6 EME27051.1 - 0.11 12.9 0.6 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal B-block_TFIIIC PF04182.7 EME27051.1 - 0.11 12.3 0.2 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC tRNA-synt_1 PF00133.17 EME27052.1 - 2.8e-194 646.5 0.6 2.1e-193 643.6 0.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME27052.1 - 4.7e-34 117.3 0.2 1.1e-33 116.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME27052.1 - 3.9e-22 78.4 1.3 1.7e-08 33.5 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.4 EME27052.1 - 3.4e-13 49.4 0.3 9.6e-13 48.0 0.2 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 EME27052.1 - 2.5e-06 26.8 0.0 0.0038 16.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EME27052.1 - 2.1e-05 23.8 0.0 0.00043 19.6 0.0 2.4 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EME27052.1 - 0.013 14.3 0.1 0.57 8.9 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EME27052.1 - 0.1 11.7 0.1 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Trypsin_2 PF13365.1 EME27053.1 - 1.3e-20 73.5 0.3 2.5e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EME27053.1 - 2e-15 56.4 0.1 4.1e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.21 EME27053.1 - 1.1e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ PF00595.19 EME27053.1 - 4e-06 26.9 1.1 0.00015 21.8 0.8 2.5 1 1 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EME27053.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain GRASP55_65 PF04495.9 EME27053.1 - 0.0025 17.7 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Peptidase_S29 PF02907.10 EME27053.1 - 0.056 12.9 0.3 0.27 10.7 0.0 2.2 3 0 0 3 3 3 0 Hepatitis C virus NS3 protease Carboxyl_trans PF01039.17 EME27054.1 - 1.1e-148 495.6 0.0 3e-148 494.2 0.0 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EME27054.1 - 1.4e-05 24.3 0.0 0.057 12.6 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Carboxyl_trans PF01039.17 EME27055.1 - 8.9e-154 512.4 0.0 1.1e-153 512.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EME27055.1 - 6e-06 25.6 0.0 0.054 12.6 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Ribosomal_S17 PF00366.15 EME27056.1 - 8e-14 51.4 0.1 1.5e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Patatin PF01734.17 EME27057.1 - 3.7e-25 89.0 0.4 9e-25 87.7 0.3 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase DsrC PF04358.8 EME27057.1 - 0.00013 22.1 0.0 0.016 15.4 0.0 2.6 2 0 0 2 2 2 2 DsrC like protein Oxysterol_BP PF01237.13 EME27058.1 - 1.4e-120 402.0 0.8 2e-120 401.5 0.5 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_11 PF15413.1 EME27058.1 - 1.1e-07 32.0 1.5 5.8e-07 29.7 0.3 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EME27058.1 - 4.1e-07 30.1 0.1 1.2e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EME27058.1 - 2.1e-05 24.4 0.0 0.00085 19.3 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.27 EME27059.1 - 1.6e-20 72.0 9.9 3.9e-07 29.7 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EME27059.1 - 0.0024 17.6 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.4 EME27059.1 - 0.0093 14.1 0.0 0.015 13.5 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Vps35 PF03635.12 EME27060.1 - 7.5e-139 464.1 6.4 9.5e-139 463.8 4.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 WD40 PF00400.27 EME27061.1 - 8.6e-10 38.1 8.3 0.0055 16.5 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.20 EME27063.1 - 8.9e-67 224.9 0.0 1.9e-66 223.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27063.1 - 2.1e-48 164.6 0.0 6.6e-48 163.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PP-binding PF00550.20 EME27063.1 - 9.8e-08 32.1 0.1 2.5e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Arm PF00514.18 EME27063.1 - 0.0012 18.5 0.0 0.05 13.4 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat CTI PF06934.6 EME27063.1 - 0.0029 15.9 0.8 0.0052 15.1 0.6 1.3 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) Kinase-like PF14531.1 EME27063.1 - 0.0032 16.4 0.0 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PP-binding_2 PF14573.1 EME27063.1 - 0.016 15.2 0.3 0.016 15.2 0.2 2.2 2 0 0 2 2 2 0 Acyl-carrier DUF3714 PF12508.3 EME27067.1 - 0.0045 16.4 0.1 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3714) RFPL3_antisense PF10489.4 EME27067.1 - 0.065 13.0 1.0 0.091 12.5 0.1 1.6 1 1 1 2 2 2 0 Ret finger protein-like 3 antisense G-patch PF01585.18 EME27070.1 - 4.6e-14 51.9 0.2 8.9e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EME27070.1 - 2.7e-13 49.3 0.1 9.4e-13 47.6 0.1 2.0 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EME27070.1 - 3.1e-07 30.1 1.7 1.6e-06 27.8 0.1 2.7 1 1 1 2 2 2 1 DExH-box splicing factor binding site TPR_11 PF13414.1 EME27071.1 - 8.3e-10 38.1 0.2 1.5e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EME27071.1 - 8.9e-10 37.7 0.0 0.0037 17.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EME27071.1 - 2.5e-08 33.2 0.1 0.0049 16.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME27071.1 - 0.00028 21.2 0.2 0.23 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME27071.1 - 0.00098 19.0 0.7 2.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME27071.1 - 0.0073 16.1 0.6 4.1 7.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME27071.1 - 0.0075 16.9 0.6 2.9 8.6 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME27071.1 - 0.012 15.3 0.0 2.1 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EME27071.1 - 0.014 14.1 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4589 PF15252.1 EME27071.1 - 0.071 12.9 0.4 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) TPR_6 PF13174.1 EME27071.1 - 0.1 13.0 1.7 6.4 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME27071.1 - 0.52 10.2 2.1 0.92 9.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SNARE PF05739.14 EME27072.1 - 1.4e-18 66.3 5.6 1.4e-18 66.3 3.9 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EME27072.1 - 3.8e-09 36.6 1.0 3.8e-09 36.6 0.7 3.7 4 0 0 4 4 4 1 Syntaxin YjgP_YjgQ PF03739.9 EME27072.1 - 0.00019 20.3 0.1 0.00019 20.3 0.1 1.7 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family Prominin PF05478.6 EME27072.1 - 0.0013 16.4 3.3 0.0013 16.4 2.3 1.8 1 1 1 2 2 2 1 Prominin Synaptobrevin PF00957.16 EME27072.1 - 0.025 14.1 0.4 0.025 14.1 0.3 2.8 2 0 0 2 2 2 0 Synaptobrevin BMFP PF04380.8 EME27072.1 - 0.1 12.7 0.2 0.1 12.7 0.1 4.6 5 1 0 5 5 5 0 Membrane fusogenic activity PEP-utilisers_N PF05524.8 EME27072.1 - 0.16 11.7 14.9 0.091 12.5 0.8 3.6 1 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF479 PF04336.7 EME27072.1 - 0.19 11.8 2.0 0.64 10.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF479 T2SF PF00482.18 EME27072.1 - 0.2 11.5 6.0 0.64 9.9 0.6 3.3 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Glyco_hydro_67N PF03648.9 EME27072.1 - 0.26 11.3 3.1 3.1 7.8 0.4 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Syntaxin_2 PF14523.1 EME27072.1 - 0.83 9.7 14.0 0.11 12.4 1.8 3.6 2 2 1 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.16 EME27072.1 - 1.8 8.0 19.8 0.019 14.5 3.0 3.0 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.10 EME27072.1 - 8.2 6.1 10.6 0.49 10.0 0.6 3.1 2 2 1 3 3 3 0 Sec34-like family V-SNARE PF05008.10 EME27072.1 - 8.7 6.5 23.2 8.8 6.5 0.1 5.2 4 2 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus SNARE PF05739.14 EME27073.1 - 1.4e-18 66.3 5.6 1.4e-18 66.3 3.9 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EME27073.1 - 3.8e-09 36.6 1.0 3.8e-09 36.6 0.7 3.7 4 0 0 4 4 4 1 Syntaxin YjgP_YjgQ PF03739.9 EME27073.1 - 0.00019 20.3 0.1 0.00019 20.3 0.1 1.7 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family Prominin PF05478.6 EME27073.1 - 0.0013 16.4 3.3 0.0013 16.4 2.3 1.8 1 1 1 2 2 2 1 Prominin Synaptobrevin PF00957.16 EME27073.1 - 0.025 14.1 0.4 0.025 14.1 0.3 2.8 2 0 0 2 2 2 0 Synaptobrevin BMFP PF04380.8 EME27073.1 - 0.1 12.7 0.2 0.1 12.7 0.1 4.6 5 1 0 5 5 5 0 Membrane fusogenic activity PEP-utilisers_N PF05524.8 EME27073.1 - 0.16 11.7 14.9 0.091 12.5 0.8 3.6 1 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF479 PF04336.7 EME27073.1 - 0.19 11.8 2.0 0.64 10.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF479 T2SF PF00482.18 EME27073.1 - 0.2 11.5 6.0 0.64 9.9 0.6 3.3 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F Glyco_hydro_67N PF03648.9 EME27073.1 - 0.26 11.3 3.1 3.1 7.8 0.4 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Syntaxin_2 PF14523.1 EME27073.1 - 0.83 9.7 14.0 0.11 12.4 1.8 3.6 2 2 1 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.16 EME27073.1 - 1.8 8.0 19.8 0.019 14.5 3.0 3.0 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.10 EME27073.1 - 8.2 6.1 10.6 0.49 10.0 0.6 3.1 2 2 1 3 3 3 0 Sec34-like family V-SNARE PF05008.10 EME27073.1 - 8.7 6.5 23.2 8.8 6.5 0.1 5.2 4 2 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus Acetyltransf_7 PF13508.1 EME27074.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Tubulin PF00091.20 EME27075.1 - 6.9e-74 248.3 0.0 1e-73 247.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME27075.1 - 9.3e-47 158.2 0.0 1.4e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME27075.1 - 4.6e-07 29.8 0.0 9.7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME27075.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 EME27075.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin like ubiquitin PF00240.18 EME27076.1 - 5.5e-139 451.7 20.6 2.7e-34 116.3 0.4 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EME27076.1 - 5.9e-82 269.3 17.4 8.6e-20 70.2 0.3 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME27076.1 - 1.4e-27 95.7 8.7 3.4e-05 24.0 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME27076.1 - 1.2e-21 77.1 0.3 0.0011 18.6 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME27076.1 - 7.7e-15 54.7 2.1 0.093 12.6 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME27076.1 - 1.4e-13 50.8 0.7 0.2 11.9 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EME27076.1 - 7.4e-12 45.0 4.1 0.28 11.1 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG DUF2870 PF11069.3 EME27076.1 - 1.1e-10 41.3 0.0 1.5 8.8 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 EME27076.1 - 2e-05 24.1 5.2 6.6 6.1 0.0 4.0 1 1 0 4 4 4 1 Ubiquitin-specific protease C-terminal IGR PF09597.5 EME27076.1 - 3.5e-05 23.6 0.0 33 4.4 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif FlgD_ig PF13860.1 EME27076.1 - 4.4e-05 23.1 2.1 22 4.8 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain FERM_N PF09379.5 EME27076.1 - 4.9e-05 23.2 5.9 20 5.3 0.0 5.9 4 4 0 4 4 4 0 FERM N-terminal domain YfmQ PF10787.4 EME27076.1 - 6.8e-05 22.2 1.0 19 4.5 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein from bacillus cereus group Plexin_cytopl PF08337.7 EME27076.1 - 0.0002 19.8 9.6 3.4 5.8 0.1 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain UN_NPL4 PF11543.3 EME27076.1 - 0.0009 19.4 1.6 64 3.9 0.0 4.3 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 CTDII PF01556.13 EME27076.1 - 0.0014 18.5 15.8 2.8 7.9 0.2 4.2 1 1 3 4 4 4 3 DnaJ C terminal domain GABP-alpha PF11620.3 EME27076.1 - 0.0084 16.0 4.5 53 3.8 0.0 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 EME27076.1 - 0.063 13.2 4.9 97 3.0 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) YajC PF02699.10 EME27076.1 - 0.078 12.6 7.6 33 4.2 0.0 4.1 4 0 0 4 4 4 0 Preprotein translocase subunit GDYXXLXY PF14345.1 EME27076.1 - 0.12 12.2 0.8 2.2e+02 1.6 0.0 4.1 4 0 0 4 4 4 0 GDYXXLXY protein Myosin_N PF02736.14 EME27076.1 - 9.2 6.0 10.4 1.1e+02 2.5 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain Tubulin PF00091.20 EME27077.1 - 7.3e-72 241.6 0.0 1.1e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME27077.1 - 1.2e-48 164.2 0.1 1.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME27077.1 - 5.7e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME27077.1 - 0.0026 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain eIF2A PF08662.6 EME27078.1 - 8.3e-55 185.5 4.6 1.9e-52 177.8 1.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EME27078.1 - 4.5e-08 32.6 0.0 1.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27078.1 - 7.5e-07 28.9 0.0 2.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27078.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AP2 PF00847.15 EME27078.1 - 0.039 14.1 1.4 0.71 10.0 0.0 3.4 3 0 0 3 3 3 0 AP2 domain Arf PF00025.16 EME27079.1 - 7.8e-76 253.1 0.2 9.5e-76 252.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME27079.1 - 7.3e-13 48.1 0.0 8.5e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EME27079.1 - 3.1e-12 46.0 0.0 3.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME27079.1 - 7.2e-12 44.9 0.0 8.6e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME27079.1 - 5.1e-11 41.9 0.9 4.2e-08 32.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EME27079.1 - 1.1e-07 32.3 0.0 1.6e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME27079.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EME27079.1 - 0.0061 15.6 0.2 0.014 14.4 0.1 1.5 1 1 0 2 2 2 1 6-phosphofructo-2-kinase DUF3986 PF13143.1 EME27079.1 - 0.046 14.1 0.6 0.21 12.0 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) AAA_33 PF13671.1 EME27079.1 - 0.054 13.3 0.3 0.15 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EME27079.1 - 0.21 11.2 0.9 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_pol_Rpb1_5 PF04998.12 EME27080.1 - 8.7e-82 274.4 0.0 8.7e-82 274.4 0.0 3.9 3 2 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EME27080.1 - 8.8e-59 198.1 0.1 3.9e-58 196.0 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EME27080.1 - 3.6e-35 121.0 0.1 1.9e-34 118.6 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EME27080.1 - 2.4e-24 86.2 11.6 2.8e-22 79.4 0.0 4.7 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EME27080.1 - 1.4e-19 69.8 2.0 1.5e-18 66.4 0.0 3.3 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 4 DUF4461 PF14688.1 EME27080.1 - 6.7e-12 45.3 0.3 1.9e-11 43.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.1 EME27080.1 - 3.7e-10 39.5 1.8 2.2e-09 37.0 1.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Neur_chan_memb PF02932.11 EME27081.1 - 8.3 6.2 9.3 5.9 6.7 5.2 1.6 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region F-box-like PF12937.2 EME27083.1 - 1.7e-10 40.4 0.4 4e-10 39.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME27083.1 - 6.6e-07 28.8 0.3 1.7e-06 27.5 0.2 1.6 2 0 0 2 2 2 1 F-box domain Sel1 PF08238.7 EME27083.1 - 3.4e-05 24.3 2.4 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 Sel1 repeat TPT PF03151.11 EME27084.1 - 5.4e-35 120.2 9.2 5.4e-35 120.2 6.4 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME27084.1 - 1.2e-11 44.7 24.8 4.4e-06 26.7 5.0 2.8 1 1 2 3 3 3 3 EamA-like transporter family UAA PF08449.6 EME27084.1 - 6.4e-11 41.7 20.7 2.6e-10 39.6 14.3 1.8 1 1 0 1 1 1 1 UAA transporter family TMEMspv1-c74-12 PF11044.3 EME27084.1 - 0.035 13.6 0.2 0.16 11.5 0.2 2.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pkinase PF00069.20 EME27085.1 - 6.6e-65 218.8 0.0 8.6e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27085.1 - 2e-32 112.2 0.0 3.1e-32 111.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EME27085.1 - 0.0022 17.0 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME27085.1 - 0.0047 16.6 3.0 0.11 12.2 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME27085.1 - 0.01 14.8 0.0 0.26 10.2 0.0 2.2 1 1 1 2 2 2 0 Kinase-like DnaJ PF00226.26 EME27085.1 - 0.059 13.1 0.8 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 DnaJ domain Pox_ser-thr_kin PF05445.6 EME27085.1 - 0.078 11.7 0.1 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nucleoporin_N PF08801.6 EME27086.1 - 1.9e-43 148.7 2.4 2.9e-43 148.2 1.7 1.3 1 0 0 1 1 1 1 Nup133 N terminal like YGGT PF02325.12 EME27086.1 - 0.00047 20.0 0.3 0.027 14.3 0.0 3.3 3 0 0 3 3 3 1 YGGT family Ran_BP1 PF00638.13 EME27087.1 - 1.4e-49 167.2 0.7 2.3e-49 166.4 0.5 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 EME27087.1 - 0.00017 21.1 0.6 0.00017 21.1 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) WH1 PF00568.18 EME27087.1 - 0.0025 17.5 0.1 0.015 15.0 0.1 1.9 1 1 0 1 1 1 1 WH1 domain Ribosomal_L35p PF01632.14 EME27087.1 - 0.27 11.1 4.2 0.57 10.1 2.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L35 Rpn3_C PF08375.6 EME27087.1 - 5.2 7.5 13.1 0.6 10.5 2.0 3.1 2 1 0 2 2 2 0 Proteasome regulatory subunit C-terminal Lipase_3 PF01764.20 EME27088.1 - 1.5e-18 66.7 0.0 2.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EME27088.1 - 0.00022 20.9 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME27088.1 - 0.0003 20.7 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME27088.1 - 0.00086 18.7 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EME27088.1 - 0.0011 18.6 0.1 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EME27088.1 - 0.0058 16.2 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EME27088.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EME27088.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EME27088.1 - 0.089 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Vps16_C PF04840.7 EME27089.1 - 7.7e-32 110.4 0.4 1.2e-31 109.8 0.3 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EME27089.1 - 6.1e-13 48.0 0.0 9.3e-11 40.8 0.0 2.4 2 0 0 2 2 2 2 Vps16, N-terminal region THF_DHG_CYH_C PF02882.14 EME27090.1 - 5.1e-66 220.7 0.0 7.2e-66 220.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EME27090.1 - 2.7e-41 140.2 0.2 4.9e-41 139.4 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPRY PF00622.23 EME27091.1 - 2.5e-21 76.0 0.1 5e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EME27091.1 - 3.9e-05 23.3 0.0 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EME27091.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 LisH DUF572 PF04502.8 EME27092.1 - 8.8e-61 205.9 0.4 1.1e-60 205.6 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) FTA4 PF13093.1 EME27092.1 - 0.069 12.5 3.4 0.099 12.0 2.3 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Octopine_DH PF02317.12 EME27092.1 - 0.13 11.8 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Myb_DNA-binding PF00249.26 EME27093.1 - 2.7e-13 49.7 0.1 4.7e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME27093.1 - 0.0013 18.8 0.2 0.0034 17.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain KxDL PF10241.4 EME27095.1 - 1.9e-07 30.8 2.2 2e-07 30.8 1.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein Seryl_tRNA_N PF02403.17 EME27095.1 - 0.00092 19.1 4.6 0.001 19.0 3.2 1.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EME27095.1 - 0.0019 18.0 2.7 0.0021 17.8 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EME27095.1 - 0.0066 13.8 2.2 0.0069 13.8 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CorA PF01544.13 EME27095.1 - 0.01 14.8 0.3 0.013 14.6 0.2 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LOH1CR12 PF10158.4 EME27095.1 - 0.014 15.1 0.5 0.016 14.9 0.3 1.1 1 0 0 1 1 1 0 Tumour suppressor protein Bul1_C PF04426.7 EME27095.1 - 0.016 14.3 1.6 0.019 14.1 1.1 1.0 1 0 0 1 1 1 0 Bul1 C terminus DUF2450 PF10475.4 EME27095.1 - 0.018 13.9 1.1 0.02 13.8 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Laminin_I PF06008.9 EME27095.1 - 0.018 14.3 1.0 0.021 14.1 0.7 1.1 1 0 0 1 1 1 0 Laminin Domain I UCR_hinge PF02320.11 EME27095.1 - 0.021 14.7 1.0 0.028 14.3 0.4 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF2959 PF11172.3 EME27095.1 - 0.024 14.4 0.8 0.028 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF2317 PF10079.4 EME27095.1 - 0.025 13.2 2.0 0.025 13.2 1.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) CR6_interact PF10147.4 EME27095.1 - 0.035 13.4 1.5 0.039 13.2 1.1 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Transcrip_act PF04949.8 EME27095.1 - 0.042 13.4 3.4 0.043 13.4 2.3 1.0 1 0 0 1 1 1 0 Transcriptional activator ADSL_C PF10397.4 EME27095.1 - 0.044 13.7 0.4 0.071 13.1 0.3 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus DUF948 PF06103.6 EME27095.1 - 0.045 13.6 0.7 0.055 13.3 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.5 EME27095.1 - 0.052 13.1 1.0 0.79 9.3 0.1 2.0 1 1 1 2 2 2 0 DASH complex subunit Duo1 Syntaxin PF00804.20 EME27095.1 - 0.058 13.5 2.5 0.17 12.1 1.5 1.7 1 1 0 1 1 1 0 Syntaxin GLE1 PF07817.8 EME27095.1 - 0.066 12.1 1.4 0.072 12.0 1.0 1.0 1 0 0 1 1 1 0 GLE1-like protein Orbi_VP5 PF00901.12 EME27095.1 - 0.067 11.3 1.4 0.068 11.3 1.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 BLOC1_2 PF10046.4 EME27095.1 - 0.077 13.1 2.2 0.095 12.8 1.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EME27095.1 - 0.091 13.0 1.6 0.19 12.0 1.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Drf_FH3 PF06367.11 EME27095.1 - 0.1 11.9 1.9 0.12 11.7 1.3 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Syntaxin-6_N PF09177.6 EME27095.1 - 0.12 12.8 1.1 0.16 12.3 0.8 1.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal HSCB_C PF07743.8 EME27095.1 - 0.12 12.8 1.7 0.26 11.7 1.0 1.7 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Cgr1 PF03879.9 EME27095.1 - 0.13 12.4 5.7 0.15 12.2 4.0 1.1 1 0 0 1 1 1 0 Cgr1 family TEX13 PF15186.1 EME27095.1 - 0.18 11.3 1.7 0.22 11.0 1.2 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family BAG PF02179.11 EME27095.1 - 0.25 11.4 3.6 0.19 11.8 0.4 2.1 1 1 1 2 2 2 0 BAG domain COG2 PF06148.6 EME27095.1 - 0.34 10.7 3.1 0.49 10.2 2.1 1.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Lge1 PF11488.3 EME27095.1 - 1.2 9.4 4.6 45 4.3 3.2 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 ATG27 PF09451.5 EME27096.1 - 0.035 13.3 0.9 0.035 13.3 0.6 2.4 3 0 0 3 3 3 0 Autophagy-related protein 27 EmrE PF13536.1 EME27096.1 - 5.5 7.2 25.3 0.24 11.6 4.0 3.6 1 1 1 3 3 3 0 Multidrug resistance efflux transporter Sugar_tr PF00083.19 EME27097.1 - 5.2e-90 302.1 24.2 6.5e-90 301.8 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27097.1 - 1.9e-28 99.1 28.7 7.4e-28 97.2 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2985 PF11204.3 EME27097.1 - 0.0011 18.6 1.7 0.24 11.1 0.2 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2985) DUF3433 PF11915.3 EME27097.1 - 0.0052 16.9 0.6 0.014 15.5 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Glyco_transf_90 PF05686.7 EME27098.1 - 5.8e-15 54.8 0.0 1.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Sugar_tr PF00083.19 EME27101.1 - 8.8e-89 298.1 31.6 1.1e-88 297.8 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27101.1 - 2.1e-29 102.3 59.4 8.9e-27 93.7 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EME27101.1 - 0.00035 18.8 11.7 0.00035 18.8 8.1 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector ATP1G1_PLM_MAT8 PF02038.11 EME27101.1 - 4.1 6.4 5.3 33 3.6 0.9 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PhyH PF05721.8 EME27102.1 - 3e-14 53.5 0.0 6.1e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EME27102.1 - 0.084 13.1 0.1 3.5 7.9 0.0 2.9 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase DUF2462 PF09495.5 EME27102.1 - 0.091 13.5 0.2 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Macoilin PF09726.4 EME27103.1 - 0.31 9.2 12.3 0.46 8.6 8.5 1.2 1 0 0 1 1 1 0 Transmembrane protein zf-C3HC4_3 PF13920.1 EME27103.1 - 1.6 8.4 9.8 3.2 7.4 6.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_viral_N PF00242.12 EME27103.1 - 2.2 7.2 17.9 3.1 6.7 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAP1 PF08601.5 EME27103.1 - 3.3 7.2 19.5 6.4 6.3 13.5 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 zf-C3HC4 PF00097.20 EME27103.1 - 4.6 6.9 13.2 9.9 5.9 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IF3_C PF00707.17 EME27104.1 - 6.4e-17 61.0 0.2 1.5e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EME27104.1 - 4.9e-14 52.0 0.3 9.2e-14 51.1 0.1 1.5 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Syntaxin-6_N PF09177.6 EME27104.1 - 0.005 17.2 1.4 1.2 9.6 0.0 2.6 2 1 0 2 2 2 2 Syntaxin 6, N-terminal PUA_2 PF14306.1 EME27104.1 - 0.015 14.7 0.2 0.027 13.9 0.1 1.5 1 1 0 1 1 1 0 PUA-like domain mIF3 PF14877.1 EME27104.1 - 0.033 13.5 0.1 0.059 12.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial translation initiation factor UbiA PF01040.13 EME27105.1 - 4.6e-26 91.5 14.0 7.1e-26 90.9 9.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DnaJ PF00226.26 EME27106.1 - 0.00036 20.1 0.1 0.0012 18.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.14 EME27106.1 - 1.9 6.2 5.0 3.4 5.4 3.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L7Ae PF01248.21 EME27107.1 - 2.9e-06 26.6 0.0 4.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EME27107.1 - 0.0026 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 SIR2 PF02146.12 EME27108.1 - 2.3e-55 187.0 0.0 3.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family EcoEI_R_C PF08463.5 EME27108.1 - 0.045 13.5 0.8 0.092 12.5 0.5 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal CutC PF03932.9 EME27108.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 CutC family Glyco_hydro_38 PF01074.17 EME27109.1 - 3.1e-83 279.1 0.2 6e-83 278.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EME27109.1 - 4.3e-49 167.5 0.0 6.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EME27109.1 - 1.2e-25 89.5 1.4 2.1e-25 88.7 0.1 2.1 2 0 0 2 2 2 1 Alpha mannosidase, middle domain PPR PF01535.15 EME27110.1 - 4.1e-08 32.6 0.7 0.0022 17.8 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EME27110.1 - 6.1e-07 29.2 0.1 0.062 13.6 0.0 4.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EME27110.1 - 0.00015 21.6 0.1 0.21 11.5 0.0 3.4 4 0 0 4 4 4 2 PPR repeat family PPR_1 PF12854.2 EME27110.1 - 0.013 14.9 0.0 0.72 9.3 0.0 2.6 2 0 0 2 2 2 0 PPR repeat TPR_15 PF13429.1 EME27110.1 - 0.025 13.6 0.1 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME27110.1 - 0.034 14.7 0.0 9.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME27110.1 - 0.15 12.4 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C48 PF02902.14 EME27111.1 - 2e-33 115.8 3.8 2e-33 115.8 2.6 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3595 PF12166.3 EME27112.1 - 2.4e-60 204.5 0.9 5.1e-60 203.4 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) CIAPIN1 PF05093.8 EME27114.1 - 3.5e-20 71.9 17.2 1.5e-19 69.8 9.3 3.1 1 1 1 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RE_TaqI PF09573.5 EME27114.1 - 0.014 14.5 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease Tox-REase-7 PF15649.1 EME27114.1 - 0.058 13.5 1.2 0.11 12.6 0.6 1.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 tRNA_U5-meth_tr PF05958.6 EME27114.1 - 0.059 12.0 0.1 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase zf-RING_2 PF13639.1 EME27115.1 - 2.2e-11 43.4 7.1 4e-11 42.5 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME27115.1 - 8.3e-07 28.6 5.0 2.2e-06 27.2 3.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME27115.1 - 1.1e-06 28.5 8.4 2.1e-06 27.6 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27115.1 - 4.8e-06 26.1 3.2 9.7e-06 25.1 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME27115.1 - 1.1e-05 25.0 6.5 2.6e-05 23.7 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME27115.1 - 2.1e-05 24.5 5.1 6.4e-05 22.9 3.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EME27115.1 - 0.0013 18.3 1.1 0.003 17.2 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 EME27115.1 - 0.0034 16.8 0.2 2.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-Apc11 PF12861.2 EME27115.1 - 0.0048 16.7 3.6 0.021 14.6 2.5 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EME27115.1 - 0.017 14.8 3.9 0.027 14.1 2.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EME27115.1 - 0.022 14.6 9.7 0.22 11.4 6.9 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EME27115.1 - 0.064 12.8 6.6 0.17 11.5 4.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_6 PF13912.1 EME27115.1 - 0.11 12.3 1.7 3.8 7.5 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_6 PF14835.1 EME27115.1 - 0.15 11.8 7.6 0.1 12.4 1.6 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 EME27115.1 - 2.1 8.5 7.4 17 5.6 2.7 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.1 EME27115.1 - 2.5 7.9 6.4 30 4.4 4.4 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_4 PF07975.7 EME27115.1 - 5 7.1 11.6 25 4.9 0.2 3.1 1 1 1 2 2 2 0 TFIIH C1-like domain CLP_protease PF00574.18 EME27116.1 - 2e-78 262.2 0.0 2.8e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Clp protease NODP PF07684.7 EME27116.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 NOTCH protein PCRF PF03462.13 EME27117.1 - 1.3e-38 131.2 0.2 2.9e-38 130.1 0.1 1.7 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.15 EME27117.1 - 7e-38 128.9 0.5 7e-38 128.9 0.3 1.8 2 0 0 2 2 2 1 RF-1 domain Fib_alpha PF08702.5 EME27117.1 - 0.13 12.3 1.7 0.39 10.8 1.2 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 EME27117.1 - 1.5 9.1 5.9 1.2 9.4 2.2 1.9 2 0 0 2 2 2 0 AAA domain BNIP3 PF06553.7 EME27118.1 - 0.57 9.5 7.6 0.81 9.0 5.3 1.2 1 0 0 1 1 1 0 BNIP3 DUF1675 PF07897.6 EME27118.1 - 2.7 7.7 7.6 4.1 7.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDP-OH_P_transf PF01066.16 EME27119.1 - 1.4e-18 67.0 10.7 1.4e-18 67.0 7.4 3.5 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase SecA_DEAD PF07517.9 EME27120.1 - 3.9e-95 318.1 0.4 7e-95 317.3 0.3 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.8 EME27120.1 - 6.6e-36 124.0 6.5 2e-35 122.5 4.5 1.9 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.15 EME27120.1 - 1.4e-32 112.3 1.1 3.3e-32 111.2 0.0 2.2 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.24 EME27120.1 - 0.0043 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase TelA PF05816.6 EME27120.1 - 0.057 12.1 0.9 0.14 10.8 0.6 1.6 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) ResIII PF04851.10 EME27120.1 - 0.27 11.0 1.9 0.85 9.4 0.1 2.7 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit DUF21 PF01595.15 EME27121.1 - 1.3e-38 132.1 0.1 2.3e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME27121.1 - 1.5e-08 34.2 0.1 0.0026 17.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain SET PF00856.23 EME27122.1 - 1.7e-09 38.1 0.1 4.5e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EME27122.1 - 1.2e-07 31.4 17.5 1.2e-07 31.4 12.2 2.8 3 0 0 3 3 3 1 MYND finger TPR_12 PF13424.1 EME27122.1 - 0.00037 20.3 3.6 0.0015 18.4 2.5 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME27122.1 - 0.0005 19.6 8.6 0.0055 16.4 2.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME27122.1 - 0.00099 18.8 6.9 0.0079 16.0 2.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3366 PF11846.3 EME27122.1 - 0.026 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) TPR_6 PF13174.1 EME27122.1 - 0.098 13.1 2.8 0.39 11.2 1.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME27122.1 - 0.14 11.8 3.6 0.41 10.3 2.1 2.1 1 1 1 2 2 2 0 TPR repeat TPR_19 PF14559.1 EME27122.1 - 0.24 11.7 4.0 0.58 10.5 1.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME27122.1 - 1.5 8.5 8.8 0.49 10.1 2.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EME27123.1 - 4.8e-28 95.9 0.9 4.2e-08 32.7 0.0 6.0 5 1 1 6 6 6 5 WD domain, G-beta repeat Phage-tail_1 PF09097.5 EME27123.1 - 0.0068 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Baseplate structural protein, domain 1 DUF4525 PF15027.1 EME27123.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) dUTPase_2 PF08761.6 EME27123.1 - 0.077 13.0 0.6 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 dUTPase WD40 PF00400.27 EME27124.1 - 5.3e-28 95.8 1.0 4.2e-08 32.7 0.0 6.0 5 1 1 6 6 6 5 WD domain, G-beta repeat Phage-tail_1 PF09097.5 EME27124.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Baseplate structural protein, domain 1 DUF4525 PF15027.1 EME27124.1 - 0.031 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) dUTPase_2 PF08761.6 EME27124.1 - 0.078 13.0 0.6 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 dUTPase Aa_trans PF01490.13 EME27127.1 - 9.9e-23 80.2 11.7 1.3e-22 79.9 8.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BTK PF00779.14 EME27128.1 - 4.6e-05 22.9 3.0 0.00011 21.7 2.1 1.6 1 0 0 1 1 1 1 BTK motif CHORD PF04968.7 EME27128.1 - 0.014 15.6 0.8 0.014 15.6 0.5 3.1 2 1 1 3 3 3 0 CHORD DUF2367 PF10164.4 EME27128.1 - 0.16 11.8 1.7 13 5.7 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) HEAT_2 PF13646.1 EME27129.1 - 1.3e-25 89.4 2.2 1.9e-13 50.4 0.1 3.0 1 1 2 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EME27129.1 - 3.5e-12 45.5 0.1 0.018 15.4 0.0 4.6 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat HEAT PF02985.17 EME27129.1 - 1.1e-08 34.4 0.9 0.037 14.0 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EME27129.1 - 6.8e-06 26.4 1.3 0.22 12.0 0.0 4.5 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 EME27129.1 - 0.0057 16.5 0.3 0.35 10.6 0.0 2.8 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MoeZ_MoeB PF05237.8 EME27129.1 - 0.046 13.3 0.0 0.31 10.6 0.0 2.1 1 1 1 2 2 2 0 MoeZ/MoeB domain Nipped-B_C PF12830.2 EME27129.1 - 0.059 13.0 0.2 0.86 9.2 0.0 2.6 1 1 2 3 3 3 0 Sister chromatid cohesion C-terminus UPF0016 PF01169.14 EME27130.1 - 4.7e-14 52.2 17.1 2.2e-09 37.3 3.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2975 PF11188.3 EME27130.1 - 0.058 13.1 8.3 1.1 9.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DAP10 PF07213.6 EME27130.1 - 0.71 9.6 3.0 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 DAP10 membrane protein NmrA PF05368.8 EME27131.1 - 1.1e-43 149.1 0.0 1.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME27131.1 - 2.4e-12 47.2 0.0 3.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME27131.1 - 0.00082 18.8 0.1 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EME27131.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EME27131.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EME27131.1 - 0.13 12.1 0.1 4.9 7.0 0.0 2.8 4 0 0 4 4 4 0 Dihydrodipicolinate reductase, N-terminus ATPgrasp_ST PF14397.1 EME27131.1 - 0.14 11.2 0.0 0.39 9.7 0.0 1.6 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp FAM104 PF15434.1 EME27132.1 - 0.028 14.6 0.3 0.033 14.3 0.2 1.4 1 1 0 1 1 1 0 Family 104 DLH PF01738.13 EME27133.1 - 4.1e-43 147.1 0.0 4.6e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME27133.1 - 3.5e-09 36.5 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME27133.1 - 1.6e-07 31.4 0.1 0.0058 16.5 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family BAAT_C PF08840.6 EME27133.1 - 2.2e-06 27.5 3.9 0.0034 17.1 0.2 2.4 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EME27133.1 - 0.00059 19.4 0.2 0.012 15.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EME27133.1 - 0.0012 17.3 0.0 0.0017 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME27133.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EME27133.1 - 0.0032 16.7 1.3 0.84 8.8 0.0 2.9 4 0 0 4 4 4 2 Prolyl oligopeptidase family Lipase_3 PF01764.20 EME27133.1 - 0.006 16.2 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EME27133.1 - 0.0067 16.0 0.4 0.24 10.9 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2048 PF09752.4 EME27133.1 - 0.095 11.5 1.1 0.23 10.2 0.5 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2048) DUF972 PF06156.8 EME27134.1 - 0.011 16.0 24.4 0.62 10.4 1.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF972) Med28 PF11594.3 EME27134.1 - 0.13 12.5 9.3 2.1 8.6 1.5 2.8 2 0 0 2 2 2 0 Mediator complex subunit 28 ATG16 PF08614.6 EME27134.1 - 0.22 11.3 22.6 3.2 7.5 0.2 4.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EME27134.1 - 1 8.9 0.0 1 8.9 0.0 4.2 4 1 0 4 4 4 0 Septum formation initiator Exo_endo_phos PF03372.18 EME27137.1 - 1.9e-25 90.2 0.0 2.6e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME27137.1 - 0.00051 19.6 0.0 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Polysacc_deac_1 PF01522.16 EME27138.1 - 2.5e-23 82.0 0.0 3.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MSC PF09402.5 EME27139.1 - 1.7e-36 125.6 2.6 2.2e-36 125.2 1.8 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain ENT PF03735.9 EME27139.1 - 0.012 15.3 0.8 0.024 14.3 0.5 1.5 1 0 0 1 1 1 0 ENT domain Cnd3 PF12719.2 EME27141.1 - 2.8e-48 164.4 11.7 3.1e-48 164.2 4.1 3.3 2 1 2 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EME27141.1 - 2.6e-15 56.4 4.5 3.5e-07 30.3 0.1 6.0 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 EME27141.1 - 2e-10 39.8 11.0 2.2 8.5 0.0 8.9 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EME27141.1 - 9.6e-06 25.9 7.0 0.14 12.6 0.1 6.3 4 1 3 7 7 7 2 HEAT-like repeat ERAP1_C PF11838.3 EME27141.1 - 0.014 14.6 0.5 0.081 12.1 0.4 2.2 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Reticulon PF02453.12 EME27141.1 - 0.046 13.3 0.3 6.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Reticulon zf-RING_2 PF13639.1 EME27142.1 - 1.7e-13 50.1 5.8 3.4e-13 49.2 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME27142.1 - 7.7e-12 45.1 0.7 3.8e-11 42.9 0.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME27142.1 - 7e-09 35.2 3.9 1.8e-08 33.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME27142.1 - 1e-07 31.8 5.9 2.3e-07 30.7 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27142.1 - 3.1e-07 29.9 4.0 6.2e-07 28.9 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27142.1 - 5.2e-06 26.0 3.0 9.6e-06 25.2 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME27142.1 - 0.00078 19.2 3.1 0.0024 17.6 2.1 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EME27142.1 - 0.022 14.7 2.9 0.05 13.6 2.0 1.6 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EME27142.1 - 0.12 11.9 3.0 0.31 10.6 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EME27142.1 - 0.13 12.0 1.8 0.28 10.9 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 EME27142.1 - 0.17 11.8 4.0 0.6 10.1 2.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EME27142.1 - 0.35 10.9 4.1 0.8 9.7 2.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EME27142.1 - 3.2 7.2 7.1 0.68 9.4 1.7 2.1 1 1 1 2 2 2 0 P-11 zinc finger HTH_31 PF13560.1 EME27143.1 - 0.00041 20.4 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EME27143.1 - 0.0013 18.6 0.1 0.0059 16.6 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EME27143.1 - 0.0014 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Lge1 PF11488.3 EME27143.1 - 0.016 15.3 0.9 0.052 13.7 0.6 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 HTH_23 PF13384.1 EME27143.1 - 0.07 12.8 0.1 6.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain HTH_26 PF13443.1 EME27143.1 - 0.075 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Peptidase_M20 PF01546.23 EME27145.1 - 1.5e-19 70.2 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME27145.1 - 2.9e-15 55.9 0.0 5.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4315 PF14193.1 EME27145.1 - 0.099 12.5 0.2 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Sec5 PF15469.1 EME27146.1 - 3.5e-12 46.4 4.1 3.5e-12 46.4 2.8 2.7 1 1 0 1 1 1 1 Exocyst complex component Sec5 CASP_C PF08172.7 EME27146.1 - 0.001 18.1 0.6 0.001 18.1 0.4 2.2 2 0 0 2 2 2 1 CASP C terminal PTPS PF01242.14 EME27147.1 - 4.2e-33 113.6 0.3 4.9e-33 113.4 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase OST-HTH PF12872.2 EME27147.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Zip PF02535.17 EME27148.1 - 6.7e-40 137.0 19.1 8.2e-40 136.7 13.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter TB2_DP1_HVA22 PF03134.14 EME27149.1 - 2.7e-25 87.9 0.5 4.2e-25 87.3 0.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Papilloma_E5 PF03025.9 EME27149.1 - 0.08 12.8 0.5 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 Papillomavirus E5 RNA_pol_3_Rpc31 PF11705.3 EME27150.1 - 4.4e-10 39.8 6.7 5.6e-10 39.5 4.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid PF03115.9 EME27150.1 - 0.091 10.9 2.3 0.1 10.8 1.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Adaptin_N PF01602.15 EME27151.1 - 2.3e-108 362.8 18.9 3.1e-108 362.3 13.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EME27151.1 - 2.5e-07 30.8 3.1 1.8e-06 28.1 0.3 3.4 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EME27151.1 - 0.00032 20.5 0.5 0.23 11.6 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EME27151.1 - 0.018 15.5 0.6 0.82 10.2 0.2 3.5 2 1 1 3 3 3 0 HEAT-like repeat DUF2670 PF10875.3 EME27151.1 - 0.048 13.6 0.3 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) MTHFR PF02219.12 EME27152.1 - 4.3e-119 396.8 0.0 5.5e-119 396.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S13_N PF08069.7 EME27155.1 - 2.2e-28 97.8 1.4 2.5e-28 97.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EME27155.1 - 2.3e-23 81.7 0.3 3.1e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HhH-GPD PF00730.20 EME27156.1 - 8.1e-09 35.7 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PK PF00224.16 EME27157.1 - 5.2e-146 485.7 0.1 8.1e-146 485.0 0.1 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EME27157.1 - 5.6e-19 67.8 0.0 1.7e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EME27157.1 - 5.8e-05 22.0 0.1 0.00014 20.8 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EME27157.1 - 0.075 11.9 0.0 0.5 9.2 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF2042 PF09743.4 EME27159.1 - 2.4e-65 220.5 4.8 5.3e-65 219.4 3.3 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) DRIM PF07539.7 EME27159.1 - 2.5e-10 39.9 5.5 5.7e-10 38.7 0.3 4.0 3 0 0 3 3 3 1 Down-regulated in metastasis GATA PF00320.22 EME27160.1 - 5.2e-14 51.3 2.0 8.8e-14 50.5 1.4 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-C4_ClpX PF06689.8 EME27160.1 - 0.0016 17.8 0.2 0.0035 16.8 0.1 1.5 1 0 0 1 1 1 1 ClpX C4-type zinc finger DZR PF12773.2 EME27160.1 - 0.1 12.4 2.1 0.22 11.3 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon CbiX PF01903.12 EME27161.1 - 9.8e-25 86.7 0.0 1.2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 CbiX CbiK PF06180.6 EME27161.1 - 8.5e-06 25.0 0.0 9.7e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Ferrochelatase PF00762.14 EME27161.1 - 0.077 11.9 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase MFS_1 PF07690.11 EME27162.1 - 1.3e-16 60.2 16.4 4.8e-15 55.1 7.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily LSM PF01423.17 EME27163.1 - 1.3e-12 47.1 0.3 2.8e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 LSM domain UCH PF00443.24 EME27164.1 - 1.6e-51 175.0 4.6 2.4e-51 174.4 3.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME27164.1 - 4.2e-17 62.5 12.3 9.1e-17 61.4 5.6 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF177 PF02620.12 EME27164.1 - 3.6e-12 46.3 0.4 1.5e-11 44.4 0.3 2.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1399 zf-UBP PF02148.14 EME27164.1 - 1.6e-10 40.9 2.8 1.6e-10 40.9 2.0 3.5 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein Copine PF07002.11 EME27165.1 - 2.7e-41 140.7 0.0 4.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EME27165.1 - 3.8e-06 26.8 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EME27165.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain PhosphMutase PF10143.4 EME27166.1 - 3.5e-56 189.5 0.0 5e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 EME27166.1 - 4.7e-42 144.1 0.0 5.7e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EME27166.1 - 9.2e-07 28.4 0.0 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME27166.1 - 0.021 14.0 0.0 0.34 10.0 0.0 2.1 2 0 0 2 2 2 0 Sulfatase adh_short PF00106.20 EME27167.1 - 2.2e-09 37.4 0.2 3.8e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TBCC PF07986.7 EME27168.1 - 7.9e-31 105.9 2.8 7.9e-31 105.9 1.9 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C NinF PF05810.7 EME27168.1 - 1.7 8.4 8.4 0.21 11.3 1.7 2.5 2 0 0 2 2 2 0 NinF protein Yip1 PF04893.12 EME27170.1 - 7.4e-13 48.3 23.2 9.9e-13 47.9 16.1 1.2 1 0 0 1 1 1 1 Yip1 domain bZIP_1 PF00170.16 EME27171.1 - 0.00027 20.8 1.3 0.00027 20.8 0.9 3.9 4 1 1 5 5 5 1 bZIP transcription factor HAP1_N PF04849.8 EME27171.1 - 0.0042 16.0 6.7 0.0042 16.0 4.7 2.9 2 1 1 3 3 3 1 HAP1 N-terminal conserved region ADIP PF11559.3 EME27171.1 - 0.0062 16.4 5.8 0.0062 16.4 4.1 2.8 2 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF148 PF02520.12 EME27171.1 - 0.011 15.5 4.5 2 8.2 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 DivIC PF04977.10 EME27171.1 - 0.013 14.9 10.7 3.2 7.3 0.3 3.4 2 1 1 3 3 3 0 Septum formation initiator Imm45 PF15603.1 EME27171.1 - 0.029 14.5 0.3 0.077 13.1 0.2 1.7 1 0 0 1 1 1 0 Immunity protein 45 HALZ PF02183.13 EME27171.1 - 0.041 13.5 4.7 1.2 8.8 0.0 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EME27171.1 - 0.057 13.2 0.4 0.057 13.2 0.3 3.2 1 1 1 2 2 2 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 EME27171.1 - 0.12 12.0 4.8 4.6 7.0 0.2 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain TMF_TATA_bd PF12325.3 EME27171.1 - 0.21 11.2 10.3 0.069 12.8 1.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Shugoshin_N PF07558.6 EME27171.1 - 0.59 9.8 10.2 0.81 9.4 0.4 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.3 EME27171.1 - 1.4 8.7 13.4 8.2 6.3 2.4 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 EME27171.1 - 6.3 6.8 10.9 0.63 10.0 1.1 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EME27171.1 - 7.1 5.7 11.7 2.2 7.3 3.1 2.9 3 1 0 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EME27171.1 - 8.8 6.1 16.6 0.86 9.4 4.1 2.7 2 0 0 2 2 2 0 Tropomyosin like Thiolase_N PF00108.18 EME27172.1 - 2.8e-78 262.5 0.5 5e-78 261.7 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ECH PF00378.15 EME27172.1 - 2.7e-53 180.5 0.4 6e-53 179.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 EME27172.1 - 9.9e-53 178.4 1.3 1.9e-52 177.5 0.4 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thiolase_C PF02803.13 EME27172.1 - 6.2e-45 151.5 1.2 1.6e-44 150.2 0.8 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain 3HCDH PF00725.17 EME27172.1 - 1.3e-21 76.7 1.3 2.7e-18 66.1 0.0 3.5 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ketoacyl-synt PF00109.21 EME27172.1 - 9.1e-06 25.3 0.7 4.7e-05 22.9 0.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_7 PF13241.1 EME27172.1 - 0.0017 18.5 0.1 0.0047 17.1 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Ribosomal_S24e PF01282.14 EME27172.1 - 0.017 14.9 0.1 0.72 9.6 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S24e F420_oxidored PF03807.12 EME27172.1 - 0.025 15.0 0.1 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EME27172.1 - 0.026 14.3 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EME27172.1 - 0.048 13.6 0.2 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain ACP_syn_III PF08545.5 EME27172.1 - 0.055 13.1 0.8 7.6 6.2 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ThiF PF00899.16 EME27174.1 - 1.1e-33 115.9 0.1 1.7e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EME27174.1 - 0.00017 21.1 0.0 0.00044 19.7 0.0 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain GGGtGRT PF14057.1 EME27174.1 - 0.0029 16.4 0.1 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 GGGtGRT protein UDPG_MGDP_dh_N PF03721.9 EME27174.1 - 0.024 14.0 0.8 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EME27174.1 - 0.036 13.4 0.0 0.12 11.8 0.0 2.0 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EME27174.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EME27174.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME27174.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PilJ PF13675.1 EME27175.1 - 0.024 14.9 7.0 3.3 8.0 0.0 3.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sigma70_r4_2 PF08281.7 EME27175.1 - 0.071 12.5 0.1 14 5.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 Reo_sigmaC PF04582.7 EME27175.1 - 0.15 11.1 10.3 0.29 10.2 2.9 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EME27175.1 - 0.21 11.8 10.3 1.6 9.0 0.1 4.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein WXG100 PF06013.7 EME27175.1 - 0.24 11.4 9.8 4.5 7.3 0.2 4.9 4 2 1 5 5 5 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.7 EME27175.1 - 0.66 9.7 12.5 2.6 7.8 0.9 4.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.14 EME27175.1 - 2.8 7.4 14.8 2 7.9 3.2 3.6 3 1 0 4 4 4 0 GrpE DUF2968 PF11180.3 EME27175.1 - 4.5 6.5 11.5 1.7 7.9 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 EME27175.1 - 5.3 4.7 18.4 1.4 6.6 2.4 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 EME27175.1 - 8.5 6.8 17.6 0.94 9.9 2.3 4.0 3 1 1 4 4 4 0 Syntaxin 6, N-terminal HSP90 PF00183.13 EME27176.1 - 6.4e-258 856.4 40.9 7.7e-258 856.2 28.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EME27176.1 - 9.8e-12 44.5 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME27176.1 - 2.9e-11 43.1 0.1 2.9e-11 43.1 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pterin_bind PF00809.17 EME27177.1 - 1.2e-61 207.7 0.0 1.8e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EME27177.1 - 7.3e-41 138.8 0.0 1.1e-39 135.0 0.0 2.3 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF2415 PF10313.4 EME27178.1 - 2.2e-10 40.0 0.1 4.6e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EME27178.1 - 8.3e-09 35.0 4.7 0.00041 20.1 0.3 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EME27178.1 - 0.0019 18.3 0.0 1.1 9.5 0.0 4.0 4 0 0 4 4 4 1 PQQ-like domain TFIIIC_delta PF12657.2 EME27178.1 - 0.035 13.8 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 EME27178.1 - 0.16 11.4 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain DUF839 PF05787.8 EME27178.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) SBDS_C PF09377.5 EME27179.1 - 6.1e-33 113.1 2.5 6.1e-33 113.1 1.7 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EME27179.1 - 4.6e-28 96.8 2.7 4.6e-28 96.8 1.9 2.2 2 1 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF2363 PF10155.4 EME27179.1 - 0.047 13.6 2.0 0.85 9.5 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2363) Fer4_14 PF13394.1 EME27179.1 - 0.097 12.7 0.8 19 5.2 0.0 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain SBDS_C PF09377.5 EME27180.1 - 3.3e-33 114.0 2.5 5.2e-33 113.4 1.7 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EME27180.1 - 1.1e-32 111.6 1.3 1.1e-32 111.6 0.9 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF1002 PF06207.6 EME27180.1 - 0.039 13.2 2.8 0.029 13.6 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) Fer4_14 PF13394.1 EME27180.1 - 0.084 12.9 0.9 17 5.4 0.0 3.0 2 1 0 3 3 3 0 4Fe-4S single cluster domain Arf PF00025.16 EME27180.1 - 0.12 11.6 1.5 0.28 10.4 0.2 2.1 1 1 1 2 2 2 0 ADP-ribosylation factor family GalP_UDP_transf PF01087.17 EME27183.1 - 9.2e-69 231.1 0.3 1.4e-68 230.5 0.2 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EME27183.1 - 1e-51 174.8 0.0 1.6e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EME27183.1 - 0.026 15.0 0.0 0.065 13.7 0.0 1.7 2 0 0 2 2 2 0 HIT domain Fe-ADH PF00465.14 EME27186.1 - 9.2e-34 116.6 0.0 4e-33 114.5 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME27186.1 - 1.7e-06 27.5 0.0 3.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ABM PF03992.11 EME27186.1 - 2.7e-05 24.1 0.0 0.04 13.9 0.0 2.7 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase OSCP PF00213.13 EME27187.1 - 1.5e-35 122.5 0.0 1.8e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vWA-TerF-like PF10138.4 EME27187.1 - 0.0023 17.8 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus GidB PF02527.10 EME27188.1 - 1.9e-15 56.4 0.0 2.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EME27188.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Arch_ATPase PF01637.13 EME27189.1 - 0.00091 18.9 0.4 0.0081 15.8 0.1 2.6 2 1 0 2 2 2 1 Archaeal ATPase Lipase PF00151.14 EME27191.1 - 0.15 11.2 0.8 0.17 11.0 0.5 1.0 1 0 0 1 1 1 0 Lipase Sugar_tr PF00083.19 EME27192.1 - 2.1e-89 300.1 28.1 2.5e-89 299.9 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27192.1 - 3.4e-23 81.9 29.5 3.4e-23 81.9 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EME27192.1 - 0.0013 16.9 4.2 0.0013 16.9 2.9 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3605 PF12239.3 EME27193.1 - 0.0018 18.1 3.7 0.0018 18.1 2.5 3.7 2 2 2 4 4 4 1 Protein of unknown function (DUF3605) Tropomyosin_1 PF12718.2 EME27193.1 - 0.098 12.4 59.1 0.025 14.4 8.8 4.2 2 1 0 3 3 3 0 Tropomyosin like DUF3450 PF11932.3 EME27193.1 - 5.4 6.2 32.6 2.4 7.3 0.8 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF3605 PF12239.3 EME27194.1 - 0.002 18.0 3.7 0.002 18.0 2.5 3.9 2 2 2 4 4 4 1 Protein of unknown function (DUF3605) Tropomyosin_1 PF12718.2 EME27194.1 - 0.14 12.0 59.1 0.039 13.7 9.2 4.2 2 1 0 3 3 3 0 Tropomyosin like DUF3450 PF11932.3 EME27194.1 - 5.9 6.0 32.4 2.8 7.1 0.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) HATPase_c PF02518.21 EME27195.1 - 5.3e-20 71.1 0.0 9.4e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME27195.1 - 0.00013 21.9 0.3 0.00026 20.9 0.2 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EME27195.1 - 0.031 14.7 0.0 0.08 13.4 0.0 1.6 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.1 EME27195.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L36 PF00444.13 EME27195.1 - 0.8 9.7 7.3 0.31 11.0 3.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L36 Aminotran_5 PF00266.14 EME27196.1 - 2.7e-97 325.8 0.0 3.5e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME27196.1 - 4.1e-11 42.5 0.1 6.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EME27196.1 - 7.8e-07 28.4 0.2 1.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EME27196.1 - 0.00024 20.9 0.0 0.019 14.8 0.0 3.0 3 0 0 3 3 3 1 B12 binding domain Pyridoxal_deC PF00282.14 EME27196.1 - 0.0037 15.7 0.1 0.0077 14.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Rib_5-P_isom_A PF06026.9 EME27197.1 - 1.9e-60 203.1 0.2 2.4e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EME27197.1 - 0.0041 16.7 0.3 0.076 12.6 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.8 EME27197.1 - 0.028 13.3 0.1 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain AcetylCoA_hyd_C PF13336.1 EME27198.1 - 3e-64 215.3 0.0 4.4e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EME27198.1 - 4e-22 78.9 0.0 8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CRAL_TRIO PF00650.15 EME27199.1 - 2.7e-20 72.4 0.1 6e-20 71.3 0.0 1.6 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EME27199.1 - 1.6e-06 28.1 0.1 2.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_S24 PF00717.18 EME27199.1 - 5.3e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like CRAL_TRIO_N PF03765.10 EME27199.1 - 0.0015 18.6 0.9 0.0028 17.7 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Peptidase_S26 PF10502.4 EME27199.1 - 0.0032 16.9 0.0 2 7.9 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 GATA PF00320.22 EME27199.1 - 0.014 14.7 0.4 0.014 14.7 0.3 2.0 2 0 0 2 2 2 0 GATA zinc finger Glycolytic PF00274.14 EME27200.1 - 5.3e-166 551.2 0.0 6.1e-166 551.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ribosomal_L4 PF00573.17 EME27201.1 - 8.9e-49 165.4 0.0 1.2e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Glyco_transf_90 PF05686.7 EME27201.1 - 1.5e-05 23.9 0.0 2.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Ribosomal_60s PF00428.14 EME27202.1 - 2.9e-21 75.6 2.4 3.9e-21 75.2 1.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF883 PF05957.8 EME27203.1 - 0.0053 17.1 11.1 0.27 11.6 3.8 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Zw10 PF06248.8 EME27203.1 - 0.013 13.6 8.3 0.015 13.4 5.8 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Apolipoprotein PF01442.13 EME27203.1 - 0.03 13.8 9.1 0.34 10.3 6.3 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EME27203.1 - 0.03 14.6 16.0 52 4.3 11.1 2.2 1 1 0 1 1 1 0 YtxH-like protein YojJ PF10372.4 EME27203.1 - 0.039 13.8 3.7 0.51 10.2 0.2 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus MCPsignal PF00015.16 EME27203.1 - 0.17 11.4 11.4 0.19 11.2 7.9 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Rabaptin PF03528.10 EME27203.1 - 0.24 11.2 11.6 0.33 10.9 8.0 1.2 1 0 0 1 1 1 0 Rabaptin DUF4207 PF13904.1 EME27203.1 - 0.25 10.6 14.7 0.31 10.3 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Cytochrom_C552 PF02335.10 EME27203.1 - 0.26 9.9 6.4 0.26 9.9 4.4 1.1 1 0 0 1 1 1 0 Cytochrome c552 AAA_13 PF13166.1 EME27203.1 - 0.27 9.6 10.1 0.3 9.5 7.0 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 EME27203.1 - 0.31 10.1 7.6 0.36 9.9 5.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin-6_N PF09177.6 EME27203.1 - 0.34 11.3 7.4 0.68 10.3 2.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ApoLp-III PF07464.6 EME27203.1 - 0.38 10.7 15.7 1 9.3 10.9 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) COG5 PF10392.4 EME27203.1 - 0.41 10.5 3.8 2 8.3 0.6 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.7 EME27203.1 - 0.45 10.2 8.2 0.75 9.5 5.7 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.7 EME27203.1 - 0.46 10.2 4.9 1 9.1 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MT0933_antitox PF14013.1 EME27203.1 - 0.46 10.6 8.7 2.1e+02 2.1 6.0 2.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF3708 PF12501.3 EME27203.1 - 0.49 10.2 3.3 0.6 9.9 2.3 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Cor1 PF04803.7 EME27203.1 - 0.54 10.0 6.2 0.9 9.3 4.3 1.4 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Prominin PF05478.6 EME27203.1 - 0.6 7.5 5.2 0.66 7.4 3.6 1.1 1 0 0 1 1 1 0 Prominin DUF241 PF03087.9 EME27203.1 - 0.64 9.4 8.3 0.68 9.3 5.7 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function YPEB PF14620.1 EME27203.1 - 0.65 8.9 7.2 0.66 8.9 5.0 1.0 1 0 0 1 1 1 0 YpeB sporulation TPR_MLP1_2 PF07926.7 EME27203.1 - 0.81 9.4 15.3 1.1 9.0 10.3 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4398 PF14346.1 EME27203.1 - 0.85 9.7 15.6 1.4 9.0 10.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) LMP PF04778.7 EME27203.1 - 1.2 8.9 13.5 2.7 7.7 0.5 2.1 1 1 0 2 2 2 0 LMP repeated region IncA PF04156.9 EME27203.1 - 1.3 8.6 10.3 1.9 8.0 7.2 1.3 1 1 0 1 1 1 0 IncA protein HisKA_3 PF07730.8 EME27203.1 - 1.3 9.4 5.8 16 5.9 0.1 2.8 1 1 1 2 2 2 0 Histidine kinase DUF2203 PF09969.4 EME27203.1 - 1.5 9.0 6.9 3 8.0 4.8 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3584 PF12128.3 EME27203.1 - 1.5 6.0 13.8 1.7 5.8 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ISG65-75 PF11727.3 EME27203.1 - 1.7 7.6 14.8 2 7.4 10.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Trehalase PF01204.13 EME27203.1 - 1.8 7.0 7.9 1.8 7.0 5.4 1.0 1 0 0 1 1 1 0 Trehalase Spc7 PF08317.6 EME27203.1 - 2 6.9 12.6 2.6 6.6 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF445 PF04286.7 EME27203.1 - 2.5 7.5 8.5 2.8 7.3 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AbiH PF14253.1 EME27203.1 - 2.8 7.4 6.6 3 7.3 4.6 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Hormone_1 PF00103.15 EME27203.1 - 3 7.1 8.1 4.4 6.5 1.1 2.1 1 1 0 2 2 2 0 Somatotropin hormone family ING PF12998.2 EME27203.1 - 3.9 7.8 9.3 6.9 7.0 0.3 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4404 PF14357.1 EME27203.1 - 4.5 7.7 8.7 1.7 9.1 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ApoC-I PF04691.7 EME27203.1 - 4.7 6.9 9.9 17 5.2 3.1 2.6 2 2 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Ku_C PF03730.9 EME27203.1 - 5 7.7 8.4 13 6.4 5.8 1.7 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm Phage_GP20 PF06810.6 EME27203.1 - 5.3 6.4 14.7 2.2 7.6 6.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 EME27203.1 - 6.1 5.7 11.2 17 4.2 7.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 EME27203.1 - 7 6.7 16.0 38 4.3 10.6 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 EME27203.1 - 7.5 6.4 9.5 5.8e+02 0.3 6.6 2.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HAUS6_N PF14661.1 EME27203.1 - 9.4 5.5 11.2 9.9 5.4 7.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YtxH PF12732.2 EME27204.1 - 4.8e-05 23.6 15.8 0.0011 19.3 2.5 2.2 1 1 1 2 2 2 2 YtxH-like protein DUF883 PF05957.8 EME27204.1 - 0.0002 21.7 6.7 0.0098 16.2 0.3 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 EME27204.1 - 0.0011 18.8 0.1 0.0021 17.9 0.0 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EME27204.1 - 0.0012 18.4 6.0 0.0023 17.4 4.2 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.6 EME27204.1 - 0.0015 17.7 8.3 0.0019 17.4 5.7 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin UvrD_C PF13361.1 EME27204.1 - 0.0035 16.8 2.8 0.0041 16.6 1.9 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF948 PF06103.6 EME27204.1 - 0.0077 16.0 6.2 0.048 13.5 2.4 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.16 EME27204.1 - 0.0081 15.7 4.4 0.016 14.7 3.1 1.4 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Senescence PF06911.7 EME27204.1 - 0.0088 15.7 1.1 0.011 15.5 0.8 1.2 1 0 0 1 1 1 1 Senescence-associated protein AAA_13 PF13166.1 EME27204.1 - 0.011 14.2 6.9 0.012 14.0 4.8 1.0 1 0 0 1 1 1 0 AAA domain HsbA PF12296.3 EME27204.1 - 0.012 15.4 0.2 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Pex19 PF04614.7 EME27204.1 - 0.012 15.2 6.2 0.017 14.7 4.3 1.3 1 0 0 1 1 1 0 Pex19 protein family FliJ PF02050.11 EME27204.1 - 0.014 15.4 4.2 0.017 15.2 2.7 1.3 1 1 0 1 1 1 0 Flagellar FliJ protein Syntaxin_2 PF14523.1 EME27204.1 - 0.023 14.7 2.8 0.03 14.3 1.5 1.5 1 1 0 1 1 1 0 Syntaxin-like protein Atg14 PF10186.4 EME27204.1 - 0.026 13.4 2.8 0.029 13.3 2.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 EME27204.1 - 0.028 14.4 3.2 0.42 10.6 0.1 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 EME27204.1 - 0.033 14.5 3.0 0.17 12.3 1.5 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2317 PF10079.4 EME27204.1 - 0.035 12.7 4.1 0.039 12.5 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) ApoLp-III PF07464.6 EME27204.1 - 0.059 13.3 11.2 0.091 12.7 7.8 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Cytochrom_C_2 PF01322.15 EME27204.1 - 0.075 13.5 8.1 0.11 12.9 5.6 1.3 1 0 0 1 1 1 0 Cytochrome C' Prominin PF05478.6 EME27204.1 - 0.085 10.3 2.6 0.15 9.5 0.9 1.4 1 1 0 1 1 1 0 Prominin TMP_2 PF06791.8 EME27204.1 - 0.13 11.8 2.4 0.29 10.7 1.0 1.9 1 1 1 2 2 2 0 Prophage tail length tape measure protein Phage_GPO PF05929.6 EME27204.1 - 0.13 11.4 4.8 0.18 11.0 3.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SLA_LP_auto_ag PF05889.8 EME27204.1 - 0.14 10.6 3.3 0.16 10.4 0.2 1.9 1 1 1 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Hormone_1 PF00103.15 EME27204.1 - 0.16 11.2 2.5 0.27 10.5 1.3 1.7 1 1 0 1 1 1 0 Somatotropin hormone family LXG PF04740.7 EME27204.1 - 0.19 11.4 7.3 0.38 10.5 5.1 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily DUF4473 PF14747.1 EME27204.1 - 0.27 11.4 11.1 0.18 12.0 3.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) ISG65-75 PF11727.3 EME27204.1 - 0.31 10.0 14.5 0.25 10.3 8.9 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Gp-FAR-1 PF05823.7 EME27204.1 - 0.33 10.8 9.5 0.58 10.0 6.6 1.5 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TMPIT PF07851.8 EME27204.1 - 0.37 9.8 6.4 0.48 9.4 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein IL10 PF00726.12 EME27204.1 - 0.4 9.9 3.6 1.4 8.2 0.1 2.5 1 1 1 2 2 2 0 Interleukin 10 HisKA_3 PF07730.8 EME27204.1 - 0.5 10.7 1.9 31 4.9 0.1 2.5 1 1 1 2 2 2 0 Histidine kinase V_ATPase_I PF01496.14 EME27204.1 - 0.52 8.1 5.1 0.6 7.8 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Muted PF14942.1 EME27204.1 - 0.59 10.0 9.2 0.82 9.5 6.4 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ParB PF08775.5 EME27204.1 - 0.6 10.4 8.2 0.53 10.5 4.5 1.7 1 1 1 2 2 2 0 ParB family Laminin_II PF06009.7 EME27204.1 - 0.62 9.8 7.1 1.5 8.5 4.9 1.6 1 1 0 1 1 1 0 Laminin Domain II Syntaxin PF00804.20 EME27204.1 - 0.76 9.9 8.6 0.6 10.2 4.1 2.0 1 1 1 2 2 2 0 Syntaxin Phasin PF05597.6 EME27204.1 - 0.82 9.4 15.5 1.1 9.0 2.3 2.1 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) THOC7 PF05615.8 EME27204.1 - 0.84 9.9 8.2 0.085 13.1 0.4 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Peptidase_M32 PF02074.10 EME27204.1 - 0.96 7.9 7.8 1.1 7.8 5.0 1.3 1 1 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF1515 PF07439.6 EME27204.1 - 1.2 8.9 7.0 4.6 7.0 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF848 PF05852.6 EME27204.1 - 1.2 8.9 10.7 6.3 6.6 7.4 1.9 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 EME27204.1 - 1.9 8.6 5.6 3.7 7.6 3.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family LUC7 PF03194.10 EME27204.1 - 2.1 7.8 10.3 5.1 6.5 7.1 1.6 1 1 0 1 1 1 0 LUC7 N_terminus Ly49 PF08391.5 EME27204.1 - 2.2 8.4 4.5 3.2 7.9 3.1 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region RRF PF01765.14 EME27204.1 - 2.3 7.6 13.0 7.4 6.0 8.9 1.8 1 1 0 1 1 1 0 Ribosome recycling factor Seryl_tRNA_N PF02403.17 EME27204.1 - 3.7 7.6 14.0 0.49 10.4 3.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2229 PF09989.4 EME27204.1 - 4.2 6.7 6.2 15 4.9 4.3 1.9 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) LMBR1 PF04791.11 EME27204.1 - 5.5 5.4 5.8 6.6 5.1 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2458 PF10454.4 EME27204.1 - 5.6 6.8 9.3 14 5.5 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) COG2 PF06148.6 EME27204.1 - 6.6 6.6 8.3 1.1e+02 2.6 5.7 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MT0933_antitox PF14013.1 EME27204.1 - 9.4 6.4 7.8 21 5.3 4.2 2.5 1 1 1 2 2 2 0 MT0933-like antitoxin protein Med1 PF10744.4 EME27205.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 PT-TG PF14449.1 EME27205.1 - 0.11 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin TG CWC25 PF12542.3 EME27206.1 - 2.5e-15 56.7 4.1 2.5e-15 56.7 2.9 4.3 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EME27206.1 - 5.8e-13 48.6 11.3 5.8e-13 48.6 7.9 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR LAT PF15234.1 EME27206.1 - 0.71 9.3 5.4 1.6 8.1 3.8 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells BLOC1_2 PF10046.4 EME27207.1 - 0.0059 16.7 4.7 0.098 12.8 0.4 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.10 EME27207.1 - 0.016 14.9 17.0 0.016 14.9 4.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper MerR_1 PF13411.1 EME27207.1 - 0.016 14.9 1.9 0.033 13.9 1.3 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein ADIP PF11559.3 EME27207.1 - 0.027 14.3 9.7 0.035 14.0 6.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Terpene_synth PF01397.16 EME27207.1 - 0.033 13.5 1.5 0.045 13.1 0.9 1.3 1 1 0 1 1 1 0 Terpene synthase, N-terminal domain DUF1875 PF08961.5 EME27207.1 - 0.045 13.0 3.2 0.038 13.2 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) Tropomyosin_1 PF12718.2 EME27207.1 - 0.048 13.5 12.5 0.046 13.5 8.0 1.3 1 1 0 1 1 1 0 Tropomyosin like NDUF_B5 PF09781.4 EME27207.1 - 0.056 12.7 2.0 0.064 12.5 1.4 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit IncA PF04156.9 EME27207.1 - 0.058 12.9 14.1 0.084 12.4 9.8 1.2 1 0 0 1 1 1 0 IncA protein DUF4164 PF13747.1 EME27207.1 - 0.059 13.5 10.7 0.09 12.9 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Fmp27_WPPW PF10359.4 EME27207.1 - 0.067 11.5 6.1 0.075 11.4 4.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mnd1 PF03962.10 EME27207.1 - 0.096 12.3 8.3 0.11 12.1 5.8 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4618 PF15397.1 EME27207.1 - 0.11 11.8 7.5 0.15 11.4 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) APG6 PF04111.7 EME27207.1 - 0.17 10.8 10.7 0.19 10.7 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin PF02996.12 EME27207.1 - 0.24 11.0 9.5 0.34 10.5 2.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EME27207.1 - 0.3 10.8 12.2 0.39 10.4 8.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.6 EME27207.1 - 0.3 10.9 13.5 0.96 9.3 9.4 1.8 1 1 0 1 1 1 0 Rabaptin-like protein Anti-adapt_IraP PF10796.4 EME27207.1 - 0.31 11.4 2.3 0.35 11.2 0.5 1.8 1 1 1 2 2 2 0 Sigma-S stabilisation anti-adaptor protein FlxA PF14282.1 EME27207.1 - 0.36 10.7 4.7 0.62 10.0 2.9 1.5 1 1 0 1 1 1 0 FlxA-like protein TBPIP PF07106.8 EME27207.1 - 0.39 10.2 9.5 1.2 8.7 2.4 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EME27207.1 - 0.48 8.2 7.5 0.53 8.0 5.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 EME27207.1 - 0.49 9.6 2.4 0.5 9.6 1.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Prefoldin_2 PF01920.15 EME27207.1 - 0.51 10.1 12.6 1.1 8.9 2.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit Kinetocho_Slk19 PF12709.2 EME27207.1 - 0.51 10.4 11.5 0.45 10.6 1.8 2.2 1 1 1 2 2 2 0 Central kinetochore-associated KIP1 PF07765.7 EME27207.1 - 0.52 10.1 4.6 2.4 8.0 0.7 2.1 1 1 1 2 2 2 0 KIP1-like protein GrpE PF01025.14 EME27207.1 - 0.65 9.5 11.4 0.35 10.4 3.2 2.0 1 1 1 2 2 2 0 GrpE KfrA_N PF11740.3 EME27207.1 - 0.67 10.4 8.8 1.4 9.3 6.1 1.7 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term YlqD PF11068.3 EME27207.1 - 0.74 9.8 9.0 1.9 8.5 6.1 1.7 1 1 0 1 1 1 0 YlqD protein PilJ PF13675.1 EME27207.1 - 0.96 9.7 4.1 1.5 9.2 2.3 1.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fzo_mitofusin PF04799.8 EME27207.1 - 1.2 8.4 5.3 0.47 9.8 1.0 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF342 PF03961.8 EME27207.1 - 1.2 7.4 8.7 1.2 7.4 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MbeD_MobD PF04899.7 EME27207.1 - 1.2 9.0 6.7 2.4 8.1 0.2 2.3 1 1 1 2 2 2 0 MbeD/MobD like DUF2802 PF10975.3 EME27207.1 - 1.3 8.7 5.9 1.6 8.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF972 PF06156.8 EME27207.1 - 1.4 9.2 9.8 14 6.0 6.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ACCA PF03255.9 EME27207.1 - 1.7 8.1 6.6 8.4 5.9 4.2 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DMPK_coil PF08826.5 EME27207.1 - 2 8.3 15.1 8.7 6.3 7.7 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like DivIC PF04977.10 EME27207.1 - 2 7.9 10.8 6.5 6.3 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator ECM11 PF15463.1 EME27207.1 - 2.1 8.5 8.5 2.3 8.5 5.5 1.4 1 1 0 1 1 1 0 Extracellular mutant protein 11 OmpH PF03938.9 EME27207.1 - 3.1 7.7 7.4 3.4 7.6 5.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 EME27207.1 - 4 7.3 17.1 6 6.8 7.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EME27207.1 - 4.2 6.2 10.4 4.8 6.0 7.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CCDC-167 PF15188.1 EME27207.1 - 6.2 6.8 10.7 5.3 7.0 6.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2951 PF11166.3 EME27207.1 - 6.2 6.7 7.9 1.7 8.5 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF904 PF06005.7 EME27207.1 - 7.2 6.9 16.2 26 5.2 11.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) PspB PF06667.7 EME27207.1 - 7.8 6.5 6.8 1.2 9.0 0.5 2.2 1 1 1 2 2 2 0 Phage shock protein B Spc24 PF08286.6 EME27207.1 - 8 6.1 8.9 50 3.6 5.8 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 RNase_T PF00929.19 EME27208.1 - 1.9e-21 77.0 0.0 3.2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EME27208.1 - 0.0064 15.9 0.0 0.13 11.7 0.0 2.7 1 1 1 2 2 2 1 3'-5' exonuclease TFIIB PF00382.14 EME27209.1 - 7.2e-30 102.6 0.0 2.5e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EME27209.1 - 3.3e-19 68.8 9.2 7.8e-19 67.6 6.4 1.7 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EME27209.1 - 2.7e-12 45.7 4.1 2.7e-12 45.7 2.8 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 EME27209.1 - 0.0024 17.4 0.0 1.7 8.2 0.0 2.9 2 1 0 2 2 2 2 Cyclin, N-terminal domain Lar_restr_allev PF14354.1 EME27209.1 - 0.022 15.0 3.1 0.022 15.0 2.1 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 EME27209.1 - 0.035 13.6 4.9 0.12 11.8 3.4 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EME27209.1 - 0.25 11.1 6.5 0.25 11.1 2.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EME27209.1 - 0.35 10.5 8.5 0.062 12.9 2.4 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EME27209.1 - 0.97 8.7 10.7 0.091 11.9 3.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EME27209.1 - 7 6.5 9.5 20 5.0 5.0 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain PseudoU_synth_2 PF00849.17 EME27210.1 - 5.3e-17 62.1 0.0 7.9e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EME27210.1 - 3.8e-06 26.2 0.0 9.8e-06 24.9 0.0 1.8 1 0 0 1 1 1 1 S4 domain FBPase PF00316.15 EME27211.1 - 7.1e-86 287.9 0.0 8.4e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase S1 PF00575.18 EME27212.1 - 9.6e-24 83.2 1.8 2.7e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.1 EME27212.1 - 0.0085 15.9 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 S1 domain DUF22 PF01629.11 EME27212.1 - 0.036 13.5 0.3 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF22 TMF_TATA_bd PF12325.3 EME27213.1 - 0.0013 18.4 0.6 0.0031 17.2 0.4 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 EME27213.1 - 0.048 13.6 0.8 0.048 13.6 0.6 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 EME27213.1 - 0.078 13.3 2.9 2.3 8.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 EME27213.1 - 0.27 10.9 2.0 1.8 8.2 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.1 EME27213.1 - 0.91 9.4 4.9 0.32 10.9 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) LURAP PF14854.1 EME27213.1 - 2.6 7.7 7.5 0.57 9.9 0.7 2.7 2 1 0 2 2 2 0 Leucine rich adaptor protein Methyltransf_23 PF13489.1 EME27214.1 - 5.7e-13 48.8 0.0 7.3e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME27214.1 - 1.5e-10 40.8 0.7 2.2e-10 40.3 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME27214.1 - 1.1e-07 32.1 0.1 2.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.11 EME27214.1 - 1.5e-07 30.6 0.0 2.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EME27214.1 - 3.7e-07 30.5 0.2 6.6e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME27214.1 - 1.6e-06 28.4 0.1 4.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME27214.1 - 9.3e-06 26.1 0.2 1.7e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME27214.1 - 0.05 13.6 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Atg14 PF10186.4 EME27215.1 - 0.044 12.7 15.4 0.069 12.0 10.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EME27215.1 - 0.064 13.1 18.2 0.16 11.7 12.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF489 PF04356.7 EME27215.1 - 0.15 11.6 5.6 0.11 12.0 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) IncA PF04156.9 EME27215.1 - 0.37 10.3 24.5 0.15 11.6 5.0 2.2 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 EME27215.1 - 0.39 10.8 12.2 0.049 13.7 3.9 2.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 EME27215.1 - 0.49 10.1 11.1 0.94 9.2 1.9 3.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 EME27215.1 - 0.98 9.3 18.3 2.9 7.7 4.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 EME27215.1 - 1.4 8.6 11.9 1.9 8.2 1.7 3.2 1 1 2 3 3 3 0 Laminin Domain II FlaC_arch PF05377.6 EME27215.1 - 2 8.3 5.6 6 6.8 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HSBP1 PF06825.7 EME27215.1 - 2.1 8.0 5.1 7.5 6.2 0.2 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Sec2p PF06428.6 EME27215.1 - 3.9 7.3 12.5 2.1 8.2 1.3 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p SlyX PF04102.7 EME27215.1 - 4.2 7.8 11.1 0.52 10.7 0.8 2.8 3 0 0 3 3 2 0 SlyX DUF4140 PF13600.1 EME27215.1 - 5.9 7.3 9.8 13 6.2 0.1 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Med4 PF10018.4 EME27215.1 - 5.9 6.2 15.5 6.4 6.1 4.0 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.15 EME27215.1 - 6.2 6.6 14.4 3.5 7.4 2.3 2.8 1 1 1 2 2 2 0 Prefoldin subunit ALMT PF11744.3 EME27215.1 - 6.4 5.3 9.1 25 3.3 6.3 2.0 1 1 0 1 1 1 0 Aluminium activated malate transporter Nup54 PF13874.1 EME27215.1 - 7.8 6.1 11.8 6.4 6.4 1.5 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CENP-Q PF13094.1 EME27215.1 - 8.3 6.4 19.4 3.8 7.5 5.2 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6 PF04111.7 EME27215.1 - 9 5.2 19.5 0.7 8.8 7.0 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 FA_desaturase PF00487.19 EME27219.1 - 9.5e-11 41.6 33.8 9.5e-11 41.6 23.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase SNF2_N PF00176.18 EME27220.1 - 1.8e-72 243.6 0.0 3e-72 242.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME27220.1 - 5.5e-16 58.1 0.0 1.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME27220.1 - 2e-11 43.2 0.5 4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EME27220.1 - 1.2e-08 35.0 0.0 3.2e-07 30.3 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EME27220.1 - 3.7e-05 23.2 0.0 0.00011 21.7 0.0 1.9 1 1 1 2 2 2 1 DEAD/DEAH box helicase Ribosomal_S9 PF00380.14 EME27221.1 - 1.6e-37 128.4 0.2 1.8e-37 128.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_hydro_47 PF01532.15 EME27222.1 - 2.7e-112 375.7 0.0 3.1e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SBP_bac_11 PF13531.1 EME27223.1 - 5.8e-27 94.8 0.0 7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EME27223.1 - 0.015 15.0 0.0 0.055 13.1 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein PBP_like PF12727.2 EME27223.1 - 0.031 13.2 0.0 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 PBP superfamily domain Synaptobrevin PF00957.16 EME27224.1 - 1.7e-05 24.2 1.4 1.7e-05 24.2 1.0 2.0 2 0 0 2 2 2 1 Synaptobrevin Rota_NS53 PF00981.12 EME27224.1 - 0.036 12.7 0.1 0.06 11.9 0.1 1.4 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Fzo_mitofusin PF04799.8 EME27224.1 - 6.3 6.1 14.5 11 5.3 0.4 3.4 3 0 0 3 3 3 0 fzo-like conserved region SAM_1 PF00536.25 EME27225.1 - 6.8e-12 45.3 0.2 2.1e-11 43.8 0.2 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EME27225.1 - 6.4e-10 38.7 0.2 1.3e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IncA PF04156.9 EME27225.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 IncA protein Halogen_Hydrol PF10112.4 EME27225.1 - 0.035 13.5 0.6 0.07 12.5 0.0 1.7 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Tmemb_cc2 PF10267.4 EME27226.1 - 0.012 14.2 0.9 0.016 13.8 0.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Complex1_LYR_2 PF13233.1 EME27226.1 - 0.073 13.5 2.1 0.2 12.1 1.5 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Spc7 PF08317.6 EME27226.1 - 0.13 10.9 3.3 0.048 12.3 0.7 1.3 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EME27226.1 - 0.24 10.9 3.7 0.12 11.9 0.8 1.7 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 EME27226.1 - 0.69 9.7 5.5 0.11 12.3 0.7 1.9 2 0 0 2 2 2 0 Prefoldin subunit Sad1_UNC PF07738.8 EME27227.1 - 4.2e-25 88.0 0.0 9.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal MFS_1 PF07690.11 EME27227.1 - 2.4e-23 82.4 37.1 3.3e-13 49.0 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MIF4G_like PF09088.6 EME27228.1 - 1.7e-32 112.3 1.1 4.4e-32 111.0 0.7 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EME27228.1 - 6.1e-16 58.4 7.1 6.1e-16 58.4 3.8 1.8 1 1 1 2 2 2 1 MIF4G like MIF4G PF02854.14 EME27228.1 - 9.8e-05 21.8 0.0 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 MIF4G domain ANTH PF07651.11 EME27229.1 - 5.4e-23 81.0 0.2 3.9e-22 78.2 0.2 2.3 1 1 0 1 1 1 1 ANTH domain HALZ PF02183.13 EME27229.1 - 0.076 12.7 9.0 0.13 11.9 3.0 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tetraspannin PF00335.15 EME27230.1 - 2.7e-17 62.8 18.2 3.7e-17 62.3 12.6 1.1 1 0 0 1 1 1 1 Tetraspanin family SHP PF03579.8 EME27230.1 - 0.06 12.7 3.8 0.11 11.8 0.8 2.6 2 0 0 2 2 2 0 Small hydrophobic protein DUF2167 PF09935.4 EME27230.1 - 0.25 10.1 1.6 0.39 9.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) ETRAMP PF09716.5 EME27230.1 - 1.9 8.5 9.6 27 4.7 0.0 3.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Arif-1 PF06770.6 EME27230.1 - 4.5 6.6 11.1 6 6.1 7.7 1.4 1 1 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) NfeD PF01957.13 EME27230.1 - 6.5 6.8 14.3 0.78 9.8 5.2 2.4 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Yip1 PF04893.12 EME27231.1 - 1.2e-07 31.4 7.8 1.2e-07 31.4 5.4 2.0 1 1 1 2 2 2 2 Yip1 domain YIF1 PF03878.10 EME27231.1 - 0.077 12.1 4.4 0.091 11.8 2.3 1.7 1 1 0 1 1 1 0 YIF1 tRNA-synt_2 PF00152.15 EME27232.1 - 2.7e-122 407.7 0.0 3.4e-122 407.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME27232.1 - 1.8e-12 46.9 0.4 3.3e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.9 EME27232.1 - 1e-10 41.6 0.0 3.8e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.15 EME27232.1 - 1.1e-05 24.7 0.3 0.015 14.5 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EME27232.1 - 0.0017 18.0 1.4 0.1 12.1 0.9 2.6 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4539 PF15072.1 EME27232.1 - 0.039 13.6 0.1 0.27 10.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4539) tRNA-synt_2 PF00152.15 EME27233.1 - 2.7e-122 407.7 0.0 3.4e-122 407.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME27233.1 - 1.8e-12 46.9 0.4 3.3e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.9 EME27233.1 - 1e-10 41.6 0.0 3.8e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.15 EME27233.1 - 1.1e-05 24.7 0.3 0.015 14.5 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EME27233.1 - 0.0017 18.0 1.4 0.1 12.1 0.9 2.6 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4539 PF15072.1 EME27233.1 - 0.039 13.6 0.1 0.27 10.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4539) DUF92 PF01940.11 EME27235.1 - 3.4e-64 216.0 12.6 4.7e-64 215.6 8.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CTP_transf_1 PF01148.15 EME27235.1 - 0.47 10.0 13.9 2.4 7.7 9.6 2.3 1 1 0 1 1 1 0 Cytidylyltransferase family Exo_endo_phos PF03372.18 EME27236.1 - 3.8e-11 43.3 0.0 4.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME27236.1 - 0.1 12.1 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase WD-3 PF09765.4 EME27237.1 - 1.6e-17 63.7 0.1 1.8e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 WD-repeat region Flagellin_N PF00669.15 EME27238.1 - 1 9.1 17.3 2.6 7.8 0.2 3.7 2 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region Reo_sigmaC PF04582.7 EME27238.1 - 3.5 6.7 13.3 4.2 6.4 0.5 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EME27238.1 - 7.1 5.4 56.4 0.048 12.6 12.0 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Flagellin_N PF00669.15 EME27239.1 - 0.64 9.8 18.1 1.1 9.0 0.2 3.6 2 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region Reo_sigmaC PF04582.7 EME27239.1 - 1.7 7.7 14.3 1.3 8.1 0.7 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EME27239.1 - 4.9 6.0 56.7 0.034 13.0 11.6 3.2 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 EME27240.1 - 4.5e-38 130.4 0.0 1e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME27240.1 - 2.1e-05 23.7 0.0 4.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME27240.1 - 3.7e-05 23.8 0.3 0.0057 16.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EME27240.1 - 4.4e-05 23.2 0.2 0.00025 20.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME27240.1 - 8e-05 23.4 0.0 0.00024 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME27240.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EME27240.1 - 0.0016 17.2 0.9 0.0051 15.5 0.0 2.2 2 1 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 EME27240.1 - 0.0023 17.9 0.5 0.025 14.5 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EME27240.1 - 0.004 16.6 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME27240.1 - 0.0049 16.5 0.8 0.03 14.0 0.4 2.4 1 1 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EME27240.1 - 0.0094 15.3 0.5 0.52 9.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain Herp-Cyclin PF09241.5 EME27240.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Herpesviridae viral cyclin Zeta_toxin PF06414.7 EME27240.1 - 0.016 14.3 2.2 0.18 10.8 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.16 EME27240.1 - 0.022 13.9 0.9 0.046 12.8 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME27240.1 - 0.034 14.4 2.1 0.056 13.7 0.0 2.5 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.1 EME27240.1 - 0.056 13.3 1.2 0.1 12.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain YchF-GTPase_C PF06071.8 EME27241.1 - 4.8e-40 135.2 0.3 9.3e-40 134.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EME27241.1 - 1.3e-16 60.6 0.0 3.1e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME27241.1 - 6.8e-07 28.6 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EME27241.1 - 0.022 13.5 0.1 0.29 9.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein TGS PF02824.16 EME27241.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 TGS domain URO-D PF01208.12 EME27242.1 - 4e-117 390.9 0.0 5e-117 390.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) RRM_1 PF00076.17 EME27244.1 - 3.5e-14 52.1 0.1 8.3e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27244.1 - 3e-08 33.5 0.0 5.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27244.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EME27244.1 - 3.3e-06 26.4 3.7 4.8e-06 25.9 1.7 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 EME27244.1 - 0.0013 18.2 1.8 0.038 13.5 0.3 2.4 2 0 0 2 2 2 1 HeH/LEM domain Ish1 PF10281.4 EME27244.1 - 0.08 13.0 0.6 0.23 11.5 0.4 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF3940 PF13076.1 EME27244.1 - 0.17 11.4 1.2 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) RRM_1 PF00076.17 EME27245.1 - 3.3e-12 45.8 0.1 7.8e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27245.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EME27245.1 - 3.9e-06 26.2 3.7 5.4e-06 25.7 1.7 1.8 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.1 EME27245.1 - 0.00066 19.4 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.2 EME27245.1 - 0.0016 17.9 1.8 0.042 13.4 0.3 2.4 2 0 0 2 2 2 1 HeH/LEM domain DUF3940 PF13076.1 EME27245.1 - 0.19 11.2 1.2 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) GCC2_GCC3 PF07699.8 EME27246.1 - 3.4e-84 276.2 240.7 9.1e-08 31.5 6.3 21.4 4 2 15 20 20 20 18 GCC2 and GCC3 NCD3G PF07562.9 EME27246.1 - 2.3e-37 126.4 182.8 0.00048 19.7 3.4 21.1 17 3 2 20 20 20 18 Nine Cysteines Domain of family 3 GPCR LRR_4 PF12799.2 EME27246.1 - 6.4e-17 60.7 35.6 1.3e-06 27.8 1.3 6.0 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME27246.1 - 5.2e-12 45.3 30.7 3.2e-05 23.5 5.0 5.7 3 2 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EME27246.1 - 4.3e-10 38.2 42.2 0.64 10.2 0.1 12.1 10 2 2 12 12 12 6 Leucine Rich Repeat LRR_7 PF13504.1 EME27246.1 - 6.1e-05 22.5 17.3 35 5.2 0.0 9.9 10 0 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 EME27246.1 - 0.00041 20.1 39.1 7 7.0 0.1 11.8 10 2 2 12 12 12 1 Leucine Rich repeat MacB_PCD PF12704.2 EME27246.1 - 0.12 11.8 0.5 0.23 11.0 0.3 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF3756 PF12581.3 EME27246.1 - 0.26 11.0 7.7 41 3.9 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3756) SKG6 PF08693.5 EME27246.1 - 7.4 5.9 6.8 16 4.9 4.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Thymidylate_kin PF02223.12 EME27247.1 - 8.2e-33 113.3 0.0 1e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_35 PF14516.1 EME27247.1 - 0.0092 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 EME27247.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EME27247.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME27247.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.18 EME27248.1 - 2.4e-21 75.5 1.3 3.7e-21 74.9 0.9 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME27248.1 - 1e-11 44.7 0.3 1e-11 44.7 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 AXE1 PF05448.7 EME27248.1 - 0.012 14.0 0.2 2.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) CENP-X PF09415.5 EME27248.1 - 0.032 14.0 0.2 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X VP4_haemagglut PF00426.13 EME27248.1 - 0.049 11.6 0.3 0.064 11.2 0.2 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Wzz PF02706.10 EME27248.1 - 0.068 12.9 0.3 0.096 12.5 0.2 1.3 1 0 0 1 1 1 0 Chain length determinant protein TAF PF02969.12 EME27248.1 - 0.12 12.3 0.2 0.12 12.3 0.1 1.8 2 1 0 2 2 2 0 TATA box binding protein associated factor (TAF) AAA PF00004.24 EME27249.1 - 6.7e-56 188.1 0.0 6.8e-40 136.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME27249.1 - 2.9e-09 37.1 1.9 0.0013 18.8 0.4 4.2 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EME27249.1 - 4.4e-09 37.2 0.1 0.0031 18.2 0.0 3.1 2 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 EME27249.1 - 2.7e-08 32.9 0.0 0.0027 16.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EME27249.1 - 6.2e-08 32.2 0.6 0.016 14.9 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 EME27249.1 - 6.7e-08 32.3 0.1 0.00055 19.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME27249.1 - 3e-07 30.3 0.0 0.053 13.3 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 EME27249.1 - 5.9e-07 29.6 0.0 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EME27249.1 - 6.2e-07 29.7 0.0 0.0041 17.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EME27249.1 - 8.1e-07 28.9 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EME27249.1 - 1.1e-06 27.8 1.8 0.01 14.9 0.1 2.9 2 1 1 3 3 3 2 KaiC RuvB_N PF05496.7 EME27249.1 - 1.8e-06 27.2 0.0 0.036 13.1 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EME27249.1 - 1.9e-06 27.0 0.0 0.055 12.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 EME27249.1 - 3.1e-06 27.1 0.0 4e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EME27249.1 - 3.3e-06 26.8 0.7 0.055 13.0 0.1 2.8 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EME27249.1 - 4.5e-06 26.5 0.0 0.038 13.9 0.0 3.4 3 0 0 3 3 3 2 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.1 EME27249.1 - 8.5e-06 25.2 1.0 0.59 9.4 0.0 4.2 4 1 0 5 5 4 2 AAA domain Sigma54_activat PF00158.21 EME27249.1 - 1.3e-05 24.7 0.1 0.068 12.6 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 EME27249.1 - 1.4e-05 24.6 0.0 0.32 10.6 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EME27249.1 - 1.4e-05 24.3 0.0 0.0053 15.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EME27249.1 - 4.9e-05 23.0 0.8 0.084 12.5 0.0 3.4 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EME27249.1 - 6e-05 23.1 0.0 0.053 13.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EME27249.1 - 6.9e-05 22.0 0.0 0.23 10.5 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_11 PF13086.1 EME27249.1 - 0.00013 21.6 0.0 0.58 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EME27249.1 - 0.00018 21.0 0.1 0.077 12.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein CDC48_2 PF02933.12 EME27249.1 - 0.00034 20.2 0.4 0.0036 16.8 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activ_2 PF14532.1 EME27249.1 - 0.0014 18.7 0.1 9.2 6.3 0.1 3.8 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EME27249.1 - 0.0014 17.9 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 EME27249.1 - 0.0016 17.3 0.2 0.53 9.1 0.2 2.6 3 0 0 3 3 2 1 NB-ARC domain KTI12 PF08433.5 EME27249.1 - 0.006 15.8 0.0 0.78 8.8 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EME27249.1 - 0.0061 16.8 0.4 0.043 14.1 0.0 2.5 3 0 0 3 3 2 1 ABC transporter AAA_30 PF13604.1 EME27249.1 - 0.0068 15.9 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME27249.1 - 0.0088 16.0 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EME27249.1 - 0.009 15.6 0.1 0.91 9.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EME27249.1 - 0.026 14.2 0.5 4 7.0 0.1 3.1 2 1 1 3 3 3 0 Archaeal ATPase DEAD PF00270.24 EME27249.1 - 0.041 13.3 1.0 29 4.1 0.0 3.6 3 1 1 4 4 4 0 DEAD/DEAH box helicase Miro PF08477.8 EME27249.1 - 0.055 13.9 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 EME27249.1 - 0.055 13.1 0.6 11 5.6 0.0 3.1 2 1 0 2 2 2 0 NTPase GvpD PF07088.6 EME27249.1 - 0.071 11.4 0.3 1.5 7.0 0.0 2.3 2 0 0 2 2 2 0 GvpD gas vesicle protein Parvo_NS1 PF01057.12 EME27249.1 - 0.088 11.6 0.0 0.89 8.3 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF89 PF01937.14 EME27250.1 - 2.5e-76 256.7 0.4 4e-76 256.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lambda_CIII PF02061.11 EME27250.1 - 0.11 12.4 0.0 0.44 10.5 0.0 2.0 1 0 0 1 1 1 0 Lambda Phage CIII Ribosomal_S30AE PF02482.14 EME27251.1 - 1.1e-23 83.4 2.2 1.7e-23 82.8 1.5 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Arch_ATPase PF01637.13 EME27252.1 - 0.00096 18.9 0.0 0.0079 15.9 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase Aa_trans PF01490.13 EME27255.1 - 1.3e-45 155.6 39.5 1.5e-45 155.4 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME27255.1 - 1.6e-05 23.9 16.9 1.6e-05 23.9 11.7 3.3 1 1 0 3 3 3 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EME27255.1 - 5.3e-05 22.0 27.9 5.3e-05 22.0 19.3 1.6 2 0 0 2 2 2 1 Spore germination protein DUF2474 PF10617.4 EME27255.1 - 0.0064 16.0 0.1 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) VWA_CoxE PF05762.9 EME27255.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein CAP59_mtransfer PF11735.3 EME27258.1 - 8.1e-54 182.3 0.1 1.1e-53 181.9 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Nop PF01798.13 EME27259.1 - 1.1e-45 154.6 0.0 2.1e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EME27259.1 - 6.3e-30 104.1 7.6 8.8e-30 103.6 2.6 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 EME27259.1 - 3.7e-11 42.6 0.0 8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Phage_tail_S PF05069.8 EME27259.1 - 0.0095 15.7 1.9 0.024 14.4 1.2 1.7 2 0 0 2 2 2 1 Phage virion morphogenesis family RRS1 PF04939.7 EME27260.1 - 4.2e-39 133.6 0.3 4.2e-39 133.6 0.2 1.4 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Isochorismatase PF00857.15 EME27261.1 - 4e-25 88.7 0.0 2.1e-24 86.3 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 EME27262.1 - 3.7e-25 88.8 0.0 2e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Med8 PF10232.4 EME27263.1 - 0.00049 19.6 4.8 0.0006 19.3 3.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF445 PF04286.7 EME27263.1 - 0.15 11.5 2.2 0.62 9.5 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) MbeD_MobD PF04899.7 EME27263.1 - 0.18 11.7 4.7 1.3 9.0 0.0 3.0 2 1 1 3 3 3 0 MbeD/MobD like DUF2301 PF10063.4 EME27264.1 - 2.3e-35 121.7 4.5 3.8e-35 121.0 3.1 1.3 1 0 0 1 1 1 1 Uncharacterized integral membrane protein (DUF2301) DUF3165 PF11364.3 EME27264.1 - 0.069 13.2 0.4 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) Motile_Sperm PF00635.21 EME27265.1 - 1.1e-24 86.1 0.2 2e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Motile_Sperm PF00635.21 EME27266.1 - 1.2e-24 86.0 0.2 2.2e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PCI PF01399.22 EME27267.1 - 6.4e-15 55.3 1.3 1.7e-14 53.9 0.1 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EME27267.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF4285 PF14113.1 EME27267.1 - 0.097 12.6 0.1 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) ABC_tran PF00005.22 EME27268.1 - 5.2e-25 88.3 0.0 9.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EME27268.1 - 9.7e-20 70.8 30.9 2.5e-19 69.5 21.4 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EME27268.1 - 2.2e-11 44.2 0.2 8e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RRM_2 PF04059.7 EME27269.1 - 5.6e-43 144.8 0.3 1.2e-42 143.8 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 EME27269.1 - 4.8e-21 74.1 0.6 2.4e-12 46.3 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27269.1 - 1.8e-18 66.3 0.5 3.7e-07 30.0 0.1 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27269.1 - 1.3e-12 47.3 0.2 3.6e-09 36.3 0.0 3.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_E_B PF04042.11 EME27270.1 - 5.5e-33 113.9 2.0 9e-33 113.2 1.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_A_exo1 PF01612.15 EME27272.1 - 3.3e-27 95.0 0.0 4.6e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease bZIP_1 PF00170.16 EME27273.1 - 3.3e-06 26.9 17.7 5.1e-05 23.1 12.3 2.7 1 1 0 1 1 1 1 bZIP transcription factor Tropomyosin_1 PF12718.2 EME27273.1 - 0.0056 16.5 8.3 0.0056 16.5 5.8 2.1 2 0 0 2 2 2 1 Tropomyosin like bZIP_Maf PF03131.12 EME27273.1 - 0.0061 16.8 8.0 0.0061 16.8 5.6 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor MBOAT PF03062.14 EME27274.1 - 1.4e-23 83.5 21.0 1.4e-23 83.5 14.6 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF3943 PF13084.1 EME27274.1 - 0.087 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) HSF_DNA-bind PF00447.12 EME27275.1 - 9.4e-33 112.4 1.0 2.5e-32 111.1 0.1 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding IncA PF04156.9 EME27275.1 - 2.6 7.6 5.2 0.91 9.0 1.1 2.0 2 0 0 2 2 2 0 IncA protein Paf1 PF03985.8 EME27276.1 - 1.1e-40 139.7 9.7 1.4e-40 139.4 6.7 1.1 1 0 0 1 1 1 1 Paf1 Vps51 PF08700.6 EME27277.1 - 1.3e-07 31.3 3.2 1.3e-07 31.3 2.2 3.6 4 0 0 4 4 4 1 Vps51/Vps67 TORC_N PF12884.2 EME27277.1 - 0.079 13.4 0.1 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus ELMO_CED12 PF04727.8 EME27278.1 - 9.5e-25 87.1 0.2 1.9e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF2422 PF10337.4 EME27278.1 - 0.16 10.7 1.3 0.2 10.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ELMO_CED12 PF04727.8 EME27279.1 - 2.4e-36 124.8 0.6 4.2e-36 124.0 0.4 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF2422 PF10337.4 EME27279.1 - 0.36 9.5 1.4 0.53 9.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ANTH PF07651.11 EME27280.1 - 1.9e-05 23.5 0.2 3.6e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 ANTH domain WD40 PF00400.27 EME27281.1 - 1.6e-10 40.4 0.6 0.15 12.0 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat DPPIV_N PF00930.16 EME27281.1 - 0.0004 19.0 0.1 2.2 6.7 0.0 4.2 4 1 0 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EME27281.1 - 0.0067 16.1 3.5 1.5 8.4 0.0 4.4 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EME27281.1 - 0.39 10.2 2.4 12 5.5 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Phos_pyr_kin PF08543.7 EME27282.1 - 2.8e-90 301.8 0.0 3.7e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Trypsin_2 PF13365.1 EME27282.1 - 1.3e-20 73.6 0.1 2.8e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EME27282.1 - 2.4e-15 56.7 0.0 4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EME27282.1 - 3.5e-11 42.8 0.0 9.2e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PfkB PF00294.19 EME27282.1 - 1e-07 31.4 0.1 1.6e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PDZ PF00595.19 EME27282.1 - 5.7e-07 29.6 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 EME27282.1 - 5.4e-05 21.8 0.6 0.014 13.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 Carb_kinase PF01256.12 EME27282.1 - 0.0021 17.3 2.1 0.0074 15.6 1.4 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Tricorn_PDZ PF14685.1 EME27282.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain F-box-like PF12937.2 EME27283.1 - 2.4e-13 49.5 0.3 5e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EME27283.1 - 2.9e-09 36.4 2.1 1.5e-05 24.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.28 EME27283.1 - 2.8e-08 33.2 0.0 7.5e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EME27283.1 - 0.02 15.1 0.2 25 5.3 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain NGP1NT PF08153.7 EME27284.1 - 1.4e-32 112.3 0.1 3e-32 111.3 0.1 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EME27284.1 - 7e-19 67.9 0.8 2.7e-16 59.5 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME27284.1 - 3.5e-06 26.3 0.0 1.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EME27284.1 - 0.00033 19.8 0.0 0.0015 17.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Arf PF00025.16 EME27284.1 - 0.013 14.7 0.0 0.053 12.7 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EME27284.1 - 0.042 14.3 0.3 0.75 10.3 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein Dynamin_N PF00350.18 EME27284.1 - 0.67 9.7 9.3 0.32 10.7 0.1 4.1 5 1 1 6 6 6 0 Dynamin family Pyridox_oxidase PF01243.15 EME27285.1 - 3e-09 36.7 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4354 PF14263.1 EME27285.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) DUF4079 PF13301.1 EME27286.1 - 1.7e-15 57.4 12.2 9.7e-13 48.4 8.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.11 EME27286.1 - 0.00084 19.1 11.2 0.0018 18.0 7.1 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.14 EME27286.1 - 0.0018 18.3 4.7 0.64 10.1 0.5 2.5 2 1 0 2 2 2 2 Ferric reductase like transmembrane component Ni_hydr_CYTB PF01292.15 EME27286.1 - 0.0027 17.1 8.4 0.087 12.2 5.8 2.2 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 COX15-CtaA PF02628.10 EME27286.1 - 0.0028 16.5 6.7 0.0039 16.1 4.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Acyl_transf_3 PF01757.17 EME27286.1 - 0.0059 15.4 3.1 0.0079 15.0 2.1 1.1 1 0 0 1 1 1 1 Acyltransferase family Cytochrom_B_N PF00033.14 EME27286.1 - 0.012 14.9 9.1 0.1 11.9 6.3 2.2 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF4405 PF14358.1 EME27286.1 - 0.16 12.0 5.4 0.5 10.5 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) PepSY_TM_2 PF13703.1 EME27286.1 - 1.4 9.1 8.9 43 4.3 0.1 2.4 1 1 1 2 2 2 0 PepSY-associated TM helix Peptidase_M17 PF00883.16 EME27287.1 - 9.9e-73 244.7 0.0 1.3e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17 PF00883.16 EME27288.1 - 6.5e-84 281.4 0.0 8.6e-84 281.0 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Symplekin_C PF12295.3 EME27289.1 - 0.23 11.3 1.6 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Symplekin_C PF12295.3 EME27290.1 - 0.23 11.3 1.6 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Ribosomal_L10 PF00466.15 EME27291.1 - 5.1e-22 77.6 0.2 2e-21 75.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Dus PF01207.12 EME27292.1 - 4.9e-59 199.6 0.0 5.9e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) T4_deiodinase PF00837.12 EME27292.1 - 0.049 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Aconitase PF00330.15 EME27293.1 - 4.4e-12 45.2 0.0 5.4e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME27293.1 - 0.00066 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PAP2 PF01569.16 EME27294.1 - 4.5e-08 32.8 8.3 4.5e-08 32.8 5.8 2.3 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EME27294.1 - 0.29 10.6 11.7 1.5 8.2 8.1 2.0 1 1 0 1 1 1 0 PAP2 superfamily RRM_1 PF00076.17 EME27295.1 - 7.7e-12 44.6 0.1 1.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27295.1 - 5.8e-08 32.6 0.0 8.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27295.1 - 8e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EME27296.1 - 7.9e-16 57.2 0.1 0.01 15.6 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat zf-CCHC PF00098.18 EME27296.1 - 8.7e-06 25.4 4.9 0.044 13.7 0.4 2.7 2 0 0 2 2 2 2 Zinc knuckle AKNA PF12443.3 EME27296.1 - 0.025 14.5 0.2 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor eIF3g PF12353.3 EME27296.1 - 0.16 11.9 9.2 0.13 12.2 0.7 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 EME27296.1 - 0.26 10.8 5.1 3.2 7.3 0.4 2.6 1 1 1 2 2 2 0 Zinc knuckle SprT-like PF10263.4 EME27297.1 - 5.9e-34 116.9 4.9 7.2e-34 116.7 3.4 1.1 1 0 0 1 1 1 1 SprT-like family HSP70 PF00012.15 EME27298.1 - 8.3e-282 935.5 4.1 9.8e-282 935.2 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME27298.1 - 4e-16 58.5 0.1 1.4e-13 50.1 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EME27298.1 - 0.0021 17.8 9.1 0.93 9.3 0.0 4.9 4 1 0 4 4 4 1 Cell division protein FtsA Macoilin PF09726.4 EME27298.1 - 0.067 11.4 12.4 0.1 10.8 8.6 1.3 1 0 0 1 1 1 0 Transmembrane protein FGGY_C PF02782.11 EME27298.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4613 PF15390.1 EME27298.1 - 0.5 8.4 5.6 0.74 7.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fmp27_WPPW PF10359.4 EME27298.1 - 6 5.1 10.6 9.4 4.5 7.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Glyco_transf_90 PF05686.7 EME27299.1 - 1.4e-15 56.9 4.4 7.1e-15 54.5 3.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 90 CENP-T PF15511.1 EME27299.1 - 0.00047 19.5 1.9 0.00071 18.9 1.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Glyco_transf_90 PF05686.7 EME27300.1 - 1.6e-18 66.5 1.6 4.2e-18 65.2 1.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 90 CENP-T PF15511.1 EME27300.1 - 0.00045 19.5 1.9 0.00068 19.0 1.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T HABP4_PAI-RBP1 PF04774.10 EME27301.1 - 0.017 15.5 2.3 0.036 14.5 1.6 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family GATase PF00117.23 EME27302.1 - 1e-42 145.7 0.0 1.6e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EME27302.1 - 4.1e-40 135.3 0.1 8.8e-40 134.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EME27302.1 - 6.8e-11 41.5 0.1 3e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EME27302.1 - 1e-08 34.8 0.0 5.6e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 EME27302.1 - 3.1e-05 23.5 0.0 7.7e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EME27302.1 - 0.0037 16.7 0.1 0.0076 15.7 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EME27302.1 - 0.0092 14.5 0.1 0.015 13.8 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 EME27302.1 - 0.014 14.6 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 EME27302.1 - 0.047 13.1 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 PP-loop family WD40 PF00400.27 EME27303.1 - 4e-34 115.2 9.2 3.6e-06 26.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Hira PF07569.6 EME27303.1 - 0.014 14.5 0.0 0.057 12.6 0.0 2.0 2 0 0 2 2 2 0 TUP1-like enhancer of split Lactonase PF10282.4 EME27303.1 - 0.05 12.6 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Ribosomal_L36e PF01158.13 EME27304.1 - 3.7e-38 129.4 7.5 4.7e-38 129.1 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RRM_1 PF00076.17 EME27305.1 - 2.5e-12 46.2 0.1 4.4e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27305.1 - 3.8e-11 42.6 0.1 8.3e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27305.1 - 1.6e-10 40.7 0.0 3.3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME27305.1 - 0.00093 18.9 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EME27305.1 - 0.0021 17.6 2.9 0.0021 17.6 2.0 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EME27305.1 - 0.0057 16.4 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif FYVE PF01363.16 EME27305.1 - 0.019 14.8 1.0 0.019 14.8 0.7 1.7 2 0 0 2 2 2 0 FYVE zinc finger EF-hand_7 PF13499.1 EME27306.1 - 1e-16 60.8 5.4 2.6e-16 59.5 2.6 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EME27306.1 - 0.00017 20.6 3.6 0.012 14.9 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EME27306.1 - 0.0016 18.1 1.4 0.11 12.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EME27306.1 - 0.0019 17.4 0.0 0.0087 15.3 0.0 2.2 1 0 0 1 1 1 1 EF hand TMV_coat PF00721.16 EME27306.1 - 0.022 14.6 0.3 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Virus coat protein (TMV like) EF-hand_8 PF13833.1 EME27306.1 - 0.12 12.0 4.0 0.81 9.3 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain pair Glycos_transf_2 PF00535.21 EME27307.1 - 5.4e-11 42.4 0.0 9.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME27307.1 - 4.6e-05 23.3 0.1 0.00011 22.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 UPRTase PF14681.1 EME27308.1 - 2.3e-78 262.1 0.0 2.7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EME27308.1 - 4.8e-06 26.2 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1565 PF07602.6 EME27308.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Peptidase_M3_N PF08439.5 EME27310.1 - 0.19 11.7 1.3 0.49 10.4 0.5 2.0 2 0 0 2 2 2 0 Oligopeptidase F DUF2781 PF10914.3 EME27312.1 - 1.3e-16 60.6 11.5 1.6e-16 60.4 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Acyl_transf_3 PF01757.17 EME27312.1 - 0.71 8.6 15.6 1.1 8.0 10.8 1.2 1 0 0 1 1 1 0 Acyltransferase family Methyltransf_33 PF10017.4 EME27313.1 - 1.3e-34 118.8 0.1 2.3e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EME27313.1 - 0.00037 20.8 0.0 0.00092 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME27313.1 - 0.0013 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME27313.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EME27313.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RNase_H PF00075.19 EME27315.1 - 2.5e-29 102.2 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EME27315.1 - 2.8e-11 43.2 0.2 5.9e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF72 PF01904.13 EME27315.1 - 0.0036 17.0 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF72 CAF1C_H4-bd PF12265.3 EME27315.1 - 0.0085 15.9 0.6 0.019 14.8 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex FMN_red PF03358.10 EME27316.1 - 5.7e-23 81.1 0.0 8.3e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Hint PF01079.15 EME27317.1 - 3.3e-28 98.4 0.1 6.8e-28 97.3 0.1 1.4 1 1 0 1 1 1 1 Hint module tRNA-synt_1g PF09334.6 EME27317.1 - 0.00083 18.1 0.1 0.63 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DUF3452 PF11934.3 EME27317.1 - 0.0026 17.0 8.9 0.63 9.3 0.3 4.8 1 1 3 4 4 4 1 Domain of unknown function (DUF3452) PT-HINT PF07591.6 EME27317.1 - 0.0031 17.4 0.1 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 Pretoxin HINT domain Homeobox_KN PF05920.6 EME27317.1 - 0.032 13.9 0.1 0.21 11.3 0.1 2.4 1 0 0 1 1 1 0 Homeobox KN domain HemN_C PF06969.11 EME27317.1 - 0.047 13.7 0.4 9.8 6.3 0.0 3.3 3 0 0 3 3 3 0 HemN C-terminal domain Vint PF14623.1 EME27317.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Hint-domain Dapper PF15268.1 EME27317.1 - 0.14 10.8 3.8 0.18 10.5 2.6 1.0 1 0 0 1 1 1 0 Dapper HTH_19 PF12844.2 EME27317.1 - 0.54 10.3 2.9 21 5.2 0.1 4.1 2 2 1 3 3 3 0 Helix-turn-helix domain Baculo_PEP_C PF04513.7 EME27317.1 - 3.2 7.5 12.0 5.9 6.7 3.6 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Methyltrn_RNA_2 PF04013.7 EME27318.1 - 0.021 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase Sipho_Gp157 PF05565.6 EME27318.1 - 0.26 10.8 3.3 0.1 12.2 0.7 1.4 2 0 0 2 2 2 0 Siphovirus Gp157 Bromodomain PF00439.20 EME27319.1 - 8.7e-21 73.6 0.0 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.20 EME27320.1 - 8.7e-21 73.6 0.0 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Cyclin_N PF00134.18 EME27321.1 - 5.3e-12 45.4 0.3 1.1e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EME27321.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EME27321.1 - 0.018 14.9 0.1 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Glyco_transf_34 PF05637.7 EME27322.1 - 3.3e-13 49.7 3.3 7.8e-08 32.1 0.1 3.1 2 1 1 3 3 3 3 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EME27322.1 - 2e-07 30.5 0.1 3.7e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 EME27322.1 - 0.0087 15.8 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peptidase_C2 PF00648.16 EME27322.1 - 0.066 12.1 1.5 0.11 11.4 1.1 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease DUF3945 PF13101.1 EME27322.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Na_H_Exchanger PF00999.16 EME27323.1 - 2.8e-58 197.2 47.9 2.8e-58 197.2 33.2 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF3357 PF11837.3 EME27323.1 - 0.02 14.7 0.4 0.85 9.4 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Patatin PF01734.17 EME27324.1 - 1.9e-24 86.7 1.1 6.4e-24 85.0 0.8 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase DnaJ PF00226.26 EME27325.1 - 5.3e-19 67.7 0.3 1.7e-18 66.0 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4522 PF15022.1 EME27325.1 - 0.065 12.9 0.6 0.16 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Peptidase_C65 PF10275.4 EME27325.1 - 0.073 12.4 3.6 0.15 11.4 2.5 1.5 1 0 0 1 1 1 0 Peptidase C65 Otubain XPG_I_2 PF12813.2 EME27325.1 - 1.6 8.1 5.4 1.3 8.4 1.3 2.2 2 0 0 2 2 2 0 XPG domain containing NIF PF03031.13 EME27327.1 - 1.7e-24 86.2 0.3 4e-24 85.0 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EME27327.1 - 4.4e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EME27327.1 - 4.8e-07 29.8 0.0 1.8e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.1 EME27327.1 - 0.00044 20.5 0.5 0.0024 18.1 0.3 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 EME27327.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) Biotin_lipoyl PF00364.17 EME27327.1 - 0.2 11.3 0.3 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme WD40 PF00400.27 EME27328.1 - 3e-25 87.1 16.2 0.00023 20.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME27328.1 - 7.7e-05 22.4 0.2 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EME27328.1 - 0.00037 19.4 0.0 0.0023 16.8 0.0 2.0 2 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 EME27328.1 - 0.017 14.5 0.4 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.3 EME27328.1 - 0.019 13.1 0.2 2.6 6.0 0.1 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.27 EME27329.1 - 3e-25 87.1 16.2 0.00023 20.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME27329.1 - 7.7e-05 22.4 0.2 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EME27329.1 - 0.00037 19.4 0.0 0.0023 16.8 0.0 2.0 2 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.1 EME27329.1 - 0.017 14.5 0.4 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.3 EME27329.1 - 0.019 13.1 0.2 2.6 6.0 0.1 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 ABC_membrane PF00664.18 EME27331.1 - 1.7e-51 175.2 11.0 2.3e-51 174.8 7.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EME27331.1 - 5.6e-35 120.6 0.0 9.8e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EME27331.1 - 1.4e-06 27.7 0.0 6.7e-05 22.2 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 EME27331.1 - 8.8e-05 22.4 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EME27331.1 - 0.00013 22.0 0.3 0.62 9.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME27331.1 - 0.0002 20.8 0.0 0.33 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME27331.1 - 0.00027 21.7 0.1 0.00069 20.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME27331.1 - 0.00038 20.0 0.0 0.062 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_5 PF07728.9 EME27331.1 - 0.00081 19.1 0.0 0.011 15.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EME27331.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EME27331.1 - 0.0017 18.5 0.6 0.035 14.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME27331.1 - 0.0021 18.0 0.6 0.0099 15.8 0.2 2.3 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 EME27331.1 - 0.0036 15.9 0.0 0.017 13.7 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Rad17 PF03215.10 EME27331.1 - 0.004 15.9 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EME27331.1 - 0.0049 17.1 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain Tad PF13400.1 EME27331.1 - 0.0098 15.9 0.1 0.0098 15.9 0.1 2.9 3 0 0 3 3 1 1 Putative Flp pilus-assembly TadE/G-like SbcCD_C PF13558.1 EME27331.1 - 0.038 13.9 0.2 0.18 11.7 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cpn60_TCP1 PF00118.19 EME27331.1 - 0.053 12.1 0.1 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family AAA_28 PF13521.1 EME27331.1 - 0.058 13.3 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EME27331.1 - 0.093 11.9 0.1 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EME27331.1 - 0.1 12.2 0.2 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Acetyltransf_1 PF00583.19 EME27332.1 - 1.3e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME27332.1 - 3.1e-05 24.0 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME27332.1 - 0.00016 21.7 0.0 0.0012 19.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME27332.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PGAP1 PF07819.8 EME27333.1 - 2.1e-05 24.2 0.1 6.4e-05 22.6 0.0 1.9 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EME27333.1 - 0.00089 19.2 0.3 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EME27333.1 - 0.0055 16.0 0.4 0.036 13.3 0.1 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EME27333.1 - 0.028 14.1 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.17 EME27334.1 - 4.7e-47 157.4 0.0 1.1e-23 82.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27334.1 - 1.7e-34 117.6 0.0 2.8e-17 62.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27334.1 - 1.5e-30 104.7 0.0 4.8e-13 48.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EME27334.1 - 7.5e-13 48.5 0.9 3.2e-12 46.5 0.6 2.1 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 EME27334.1 - 0.0073 16.0 0.5 12 5.7 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EME27334.1 - 0.042 13.7 0.1 0.62 9.9 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif MIP-T3 PF10243.4 EME27334.1 - 0.99 7.7 26.3 1.3 7.4 18.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-AN1 PF01428.11 EME27335.1 - 5.8e-20 70.8 25.6 7.4e-14 51.3 4.1 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EME27335.1 - 2e-05 24.7 15.3 0.0026 17.9 3.6 2.6 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain TUG-UBL1 PF11470.3 EME27335.1 - 0.049 13.5 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF2180 PF09947.4 EME27335.1 - 0.28 10.9 8.5 0.71 9.6 1.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Y_phosphatase2 PF03162.8 EME27336.1 - 1.2e-39 135.2 0.0 1.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family PAS_8 PF13188.1 EME27336.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 PAS domain MFS_1 PF07690.11 EME27337.1 - 1e-57 195.4 33.8 1e-57 195.4 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EME27337.1 - 2e-05 22.8 13.4 0.00012 20.3 0.7 3.5 1 1 3 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family ADK PF00406.17 EME27338.1 - 7.6e-38 129.7 0.0 1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EME27338.1 - 1.8e-07 31.9 0.0 2.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME27338.1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME27338.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain JAB PF01398.16 EME27339.1 - 1.3e-20 73.1 0.1 3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EME27339.1 - 5.2e-15 55.5 0.2 1.2e-14 54.3 0.1 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function FlaC_arch PF05377.6 EME27339.1 - 0.015 15.1 1.0 0.032 14.1 0.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EME27339.1 - 0.15 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MS_channel PF00924.13 EME27340.1 - 5.3e-50 169.6 0.1 8.4e-50 168.9 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Fer2 PF00111.22 EME27341.1 - 0.03 14.0 0.4 0.052 13.2 0.2 1.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 EME27341.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribosomal_L7Ae PF01248.21 EME27342.1 - 3.6e-28 96.9 0.1 4.2e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EME27342.1 - 0.0011 18.8 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EME27342.1 - 0.0024 17.6 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Adenosine_kin PF04008.9 EME27342.1 - 0.046 13.2 0.0 0.093 12.2 0.0 1.5 1 1 1 2 2 2 0 Adenosine specific kinase DnaJ PF00226.26 EME27343.1 - 2.6e-09 36.6 0.0 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EME27343.1 - 0.00015 21.5 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Pam16 Reductase_C PF14759.1 EME27343.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 2 0 0 2 2 2 0 Reductase C-terminal MMR_HSR1 PF01926.18 EME27345.1 - 1.1e-17 64.0 0.8 2.2e-14 53.4 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EME27345.1 - 5.6e-09 35.4 0.0 3.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EME27345.1 - 0.00093 18.4 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EME27345.1 - 0.0041 16.2 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 AIG1 family cobW PF02492.14 EME27345.1 - 0.014 14.8 0.1 0.69 9.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EME27345.1 - 0.054 13.9 0.2 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EME27345.1 - 0.11 12.1 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EME27345.1 - 5.5 6.7 6.2 0.95 9.2 0.2 2.6 2 2 1 3 3 3 0 Dynamin family RRM_1 PF00076.17 EME27346.1 - 0.032 13.8 0.1 0.14 11.8 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27346.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EME27347.1 - 1.1e-52 178.3 0.3 2e-52 177.4 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EME27347.1 - 1.6e-12 46.7 0.0 0.0017 18.1 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME27347.1 - 0.036 12.8 0.0 0.079 11.6 0.0 1.6 1 0 0 1 1 1 0 Nup133 N terminal like CARM1 PF11531.3 EME27349.1 - 0.29 10.8 3.6 0.53 10.0 2.5 1.4 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal Tfb4 PF03850.9 EME27350.1 - 3.1e-55 187.3 1.8 3.9e-55 187.0 1.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Hormone_1 PF00103.15 EME27350.1 - 0.0094 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Somatotropin hormone family zf-Sec23_Sec24 PF04810.10 EME27350.1 - 0.045 13.3 1.0 0.12 12.0 0.4 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger VWA_2 PF13519.1 EME27350.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain zf-C2H2_6 PF13912.1 EME27350.1 - 0.12 12.2 1.1 3.7 7.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EME27350.1 - 0.63 10.4 3.4 51 4.5 0.1 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger Tfb4 PF03850.9 EME27351.1 - 3.1e-55 187.3 1.8 3.9e-55 187.0 1.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Hormone_1 PF00103.15 EME27351.1 - 0.0094 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Somatotropin hormone family zf-Sec23_Sec24 PF04810.10 EME27351.1 - 0.045 13.3 1.0 0.12 12.0 0.4 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger VWA_2 PF13519.1 EME27351.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain zf-C2H2_6 PF13912.1 EME27351.1 - 0.12 12.2 1.1 3.7 7.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EME27351.1 - 0.63 10.4 3.4 51 4.5 0.1 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger DUF1168 PF06658.7 EME27352.1 - 7.3e-25 87.1 18.2 8.2e-25 86.9 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RR_TM4-6 PF06459.7 EME27352.1 - 0.32 10.8 10.8 0.35 10.7 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_18 PF15024.1 EME27352.1 - 0.55 8.4 4.2 0.64 8.2 2.9 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 18 VIT1 PF01988.14 EME27352.1 - 0.8 9.1 2.6 1.1 8.7 1.8 1.2 1 0 0 1 1 1 0 VIT family RNA_polI_A34 PF08208.6 EME27352.1 - 1.2 8.8 18.4 1.6 8.3 12.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 APG6 PF04111.7 EME27352.1 - 2.2 7.2 13.6 2.2 7.2 9.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 GAGA_bind PF06217.7 EME27352.1 - 2.9 7.7 9.4 2.9 7.7 6.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 EME27352.1 - 3.2 5.6 9.6 3.3 5.6 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 EME27352.1 - 4.3 6.2 8.4 4.7 6.0 5.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Phlebovirus_NSM PF07246.6 EME27352.1 - 5.6 6.0 10.1 6.8 5.7 7.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3987 PF13148.1 EME27352.1 - 5.9 5.3 9.4 7 5.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HSP70 PF00012.15 EME27352.1 - 8.2 4.1 9.8 8.4 4.1 6.8 1.1 1 0 0 1 1 1 0 Hsp70 protein RNase_PH PF01138.16 EME27353.1 - 1e-30 106.7 0.0 4.1e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME27353.1 - 7.2e-22 77.1 0.0 5.8e-15 54.9 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.18 EME27353.1 - 7.5e-14 51.5 0.1 1.6e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.24 EME27353.1 - 2.3e-06 27.1 0.0 6.7e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EME27353.1 - 0.024 14.2 0.1 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 KH domain HUN PF08729.5 EME27354.1 - 1.2e-08 34.6 6.0 3.1e-08 33.3 4.2 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Kinesin PF00225.18 EME27355.1 - 1.2e-110 369.4 0.2 1.2e-110 369.4 0.1 3.6 2 1 0 3 3 3 1 Kinesin motor domain DUF3450 PF11932.3 EME27355.1 - 0.00056 19.2 10.8 0.00056 19.2 7.5 5.2 2 2 4 6 6 6 1 Protein of unknown function (DUF3450) LPP PF04728.8 EME27355.1 - 0.016 15.0 5.5 1.1 9.0 0.0 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper NTF2 PF02136.15 EME27356.1 - 3.1e-23 82.3 0.1 5.4e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 EME27356.1 - 3.5e-13 49.3 0.0 8.4e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME27356.1 - 4.8e-13 48.5 0.0 1.3e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27356.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EME27356.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase_Tyr PF07714.12 EME27357.1 - 5.8e-56 189.4 0.0 8.5e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME27357.1 - 4.3e-51 173.5 0.0 9e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain IncA PF04156.9 EME27357.1 - 0.0092 15.6 0.8 1.5 8.3 0.4 2.3 2 0 0 2 2 2 2 IncA protein EphA2_TM PF14575.1 EME27357.1 - 0.04 14.3 0.0 0.81 10.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EME27357.1 - 0.06 13.0 0.4 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 EME27357.1 - 0.12 11.9 2.0 0.3 10.6 1.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1049 PF06305.6 EME27357.1 - 0.13 11.7 0.5 0.96 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TrbL PF04610.9 EME27357.1 - 0.16 11.6 1.8 0.78 9.3 0.6 2.2 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein GAPT PF11770.3 EME27358.1 - 0.14 11.8 0.2 0.18 11.4 0.1 1.3 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) GTP_EFTU PF00009.22 EME27359.1 - 4.2e-61 205.6 0.1 5.9e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME27359.1 - 2.2e-33 114.3 0.0 4.8e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EME27359.1 - 1.2e-22 79.5 0.0 2.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME27359.1 - 2.1e-15 56.6 0.1 7.3e-15 54.8 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EME27359.1 - 1.4e-14 53.6 0.2 3.7e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EME27359.1 - 3.9e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L37e PF01907.14 EME27360.1 - 1.5e-27 95.0 9.2 2.8e-27 94.2 6.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EME27360.1 - 0.00078 19.2 1.4 0.0012 18.6 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EME27360.1 - 0.003 17.2 0.2 0.0038 16.9 0.1 1.3 1 1 0 1 1 1 1 SelR domain DUF2387 PF09526.5 EME27360.1 - 0.075 12.9 0.6 7.1 6.6 0.1 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_2 PF13240.1 EME27360.1 - 0.62 9.6 2.8 9.5 5.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Mito_fiss_reg PF05308.6 EME27361.1 - 0.01 15.2 0.2 0.01 15.2 0.1 3.1 1 1 2 3 3 3 0 Mitochondrial fission regulator KH_1 PF00013.24 EME27361.1 - 0.02 14.5 0.0 0.065 12.8 0.0 1.9 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 EME27361.1 - 0.025 14.2 0.0 0.084 12.5 0.0 1.9 1 0 0 1 1 1 0 KH domain UPF0262 PF06793.7 EME27361.1 - 0.035 13.8 0.0 9 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) Ureide_permease PF07168.6 EME27363.1 - 0.0049 15.5 0.1 1.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Ureide permease DUF2433 PF10360.4 EME27363.1 - 0.014 15.7 0.1 0.12 12.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) zf-CCCH PF00642.19 EME27364.1 - 7.2e-11 41.4 12.7 6.3e-07 28.9 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EME27364.1 - 1e-10 41.2 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME27364.1 - 9.3e-10 38.0 0.1 3.3e-08 33.0 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27364.1 - 6e-08 32.5 0.1 1.6e-06 27.9 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME27364.1 - 0.0036 17.0 0.5 0.008 15.9 0.1 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2414 PF10309.4 EME27364.1 - 0.12 12.0 0.4 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) ACOX PF01756.14 EME27365.1 - 6.4e-12 45.2 0.1 1.1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EME27365.1 - 1.5e-09 37.2 0.1 2.9e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EME27365.1 - 4.7e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.11 EME27365.1 - 0.00019 21.9 0.0 0.00087 19.8 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EME27365.1 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TFIIA_gamma_C PF02751.9 EME27366.1 - 2e-16 59.5 0.4 3.3e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EME27366.1 - 2.7e-10 39.6 0.0 6e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain CARD PF00619.16 EME27366.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain DUF3427 PF11907.3 EME27366.1 - 0.048 12.6 0.7 0.21 10.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3427) U3_assoc_6 PF08640.6 EME27366.1 - 0.055 13.2 0.2 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 PsbQ PF05757.6 EME27367.1 - 0.013 14.9 4.4 0.75 9.1 0.1 3.0 2 1 1 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF4327 PF14217.1 EME27367.1 - 0.024 14.4 0.1 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) Alpha-amylase_C PF02806.13 EME27368.1 - 6.1e-22 77.5 0.0 2e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EME27368.1 - 1.7e-18 67.1 2.7 5.4e-18 65.4 0.5 2.3 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EME27368.1 - 0.00016 21.6 0.0 0.00064 19.7 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 EME27369.1 - 5.7e-22 77.6 0.0 2e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EME27369.1 - 1.7e-18 67.0 2.8 5.3e-18 65.4 0.5 2.3 2 1 1 3 3 3 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EME27369.1 - 2.4e-08 33.8 0.0 8.4e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) adh_short PF00106.20 EME27370.1 - 1.8e-22 79.9 0.1 3.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME27370.1 - 2.7e-10 40.2 0.1 4.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME27370.1 - 8.9e-06 25.6 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME27370.1 - 0.00012 22.1 0.1 0.0011 18.9 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME27370.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 EME27370.1 - 0.0075 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus DAO PF01266.19 EME27370.1 - 0.045 12.6 0.0 0.068 12.0 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_S18 PF01084.15 EME27373.1 - 2.4e-18 65.7 0.0 4.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 CENP-S PF15630.1 EME27374.1 - 2.8e-19 69.0 0.1 3.4e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EME27374.1 - 0.0011 18.6 0.1 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EME27374.1 - 0.0015 18.5 0.1 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME27374.1 - 0.0026 17.7 0.1 0.0052 16.8 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EME27374.1 - 0.0029 16.9 0.4 0.0032 16.7 0.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Mob_synth_C PF06463.8 EME27374.1 - 0.0054 16.4 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C TAF PF02969.12 EME27374.1 - 0.092 12.7 0.1 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 EME27374.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EME27375.1 - 3.6e-19 68.7 0.1 4.3e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EME27375.1 - 0.00071 19.2 0.1 0.0017 18.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 EME27375.1 - 0.0019 18.3 0.1 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME27375.1 - 0.0028 17.6 0.1 0.0064 16.5 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EME27375.1 - 0.0035 16.6 0.4 0.0039 16.5 0.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Mob_synth_C PF06463.8 EME27375.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C TAF PF02969.12 EME27375.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) PAN_3 PF08277.7 EME27377.1 - 7.6 6.2 9.8 0.061 12.9 1.1 1.9 2 0 0 2 2 2 0 PAN-like domain DUF4460 PF14687.1 EME27379.1 - 4.8e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.26 EME27379.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain Myb_DNA-bind_3 PF12776.2 EME27380.1 - 0.11 13.1 2.4 1.5 9.4 0.2 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sugar_tr PF00083.19 EME27381.1 - 0.056 12.0 0.3 0.066 11.7 0.2 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Arch_ATPase PF01637.13 EME27384.1 - 0.00035 20.3 0.0 0.0012 18.5 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase PPR PF01535.15 EME27385.1 - 0.00092 19.0 0.0 0.063 13.2 0.0 3.0 2 0 0 2 2 2 1 PPR repeat SAM_1 PF00536.25 EME27385.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PPR_2 PF13041.1 EME27385.1 - 0.053 13.5 0.7 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 PPR repeat family AAA_22 PF13401.1 EME27387.1 - 0.026 14.6 0.0 0.35 11.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME27388.1 - 0.0045 16.7 0.1 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase IMS PF00817.15 EME27389.1 - 2.4e-36 124.7 0.0 4.3e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 EME27389.1 - 3e-05 23.8 0.0 6.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Glyoxalase_2 PF12681.2 EME27390.1 - 9.6e-34 116.2 0.0 4e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EME27390.1 - 3.2e-29 101.4 0.1 1e-13 51.3 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME27390.1 - 2.3e-13 50.0 0.0 1.6e-07 31.2 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EME27390.1 - 0.012 15.3 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Glyoxalase_3 PF13468.1 EME27390.1 - 0.11 12.4 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase-like domain DNA_gyraseB PF00204.20 EME27390.1 - 0.19 10.9 0.7 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 DNA gyrase B TFCD_C PF12612.3 EME27391.1 - 0.013 14.9 0.7 0.031 13.7 0.1 1.9 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal zf-DNA_Pol PF08996.5 EME27391.1 - 0.018 14.4 0.8 0.51 9.6 0.1 2.5 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Intein_splicing PF14890.1 EME27391.1 - 0.035 12.9 0.1 4 6.2 0.0 2.2 2 0 0 2 2 2 0 Intein splicing domain Prefoldin_2 PF01920.15 EME27391.1 - 0.07 12.8 1.1 0.98 9.2 0.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit Nexin_C PF08628.7 EME27391.1 - 0.098 12.7 0.1 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal Ras_bdg_2 PF14847.1 EME27391.1 - 0.11 12.4 0.3 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Cu_amine_oxid PF01179.15 EME27392.1 - 1.9e-161 537.4 0.0 2.4e-161 537.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EME27392.1 - 8.2e-18 64.3 0.1 1.8e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EME27392.1 - 8.5e-10 38.5 0.0 3e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain TPR_12 PF13424.1 EME27393.1 - 0.0013 18.5 0.7 0.99 9.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME27393.1 - 0.0079 16.0 1.4 0.54 10.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME27393.1 - 0.22 11.5 2.2 17 5.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.13 EME27394.1 - 7.9e-43 146.4 27.3 1e-42 146.0 18.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME27394.1 - 0.0041 15.9 14.7 0.0087 14.9 10.1 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family FixQ PF05545.6 EME27394.1 - 1.3 8.6 0.0 1.3 8.6 0.0 4.7 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ Tweety PF04906.8 EME27394.1 - 1.4 7.2 4.3 2.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Tweety Spore_permease PF03845.8 EME27394.1 - 3.1 6.3 24.7 0.62 8.6 13.6 2.4 2 1 0 2 2 2 0 Spore germination protein Fasciclin PF02469.17 EME27395.1 - 2e-13 50.4 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain COG5 PF10392.4 EME27396.1 - 1.2e-07 31.7 2.9 1.8e-07 31.1 0.8 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Cas_Csa5 PF09702.5 EME27396.1 - 0.058 13.4 0.2 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) SICA_alpha PF12887.2 EME27397.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain WD40 PF00400.27 EME27398.1 - 3.2e-55 182.1 25.4 4.7e-10 38.9 0.4 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat mTERF PF02536.9 EME27398.1 - 0.0002 20.1 0.1 0.00033 19.3 0.0 1.2 1 0 0 1 1 1 1 mTERF Nup160 PF11715.3 EME27398.1 - 0.00034 18.8 0.3 0.013 13.7 0.1 2.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 RtcR PF06956.6 EME27398.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase Nucleoporin_N PF08801.6 EME27398.1 - 0.036 12.8 0.2 6.1 5.4 0.0 3.1 1 1 1 3 3 3 0 Nup133 N terminal like Fmp27_WPPW PF10359.4 EME27398.1 - 0.087 11.2 0.3 0.12 10.7 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.7 EME27399.1 - 0.011 15.5 4.1 0.16 11.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EME27399.1 - 0.011 15.6 3.6 0.062 13.2 0.3 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2205 PF10224.4 EME27399.1 - 0.031 13.8 4.3 0.034 13.7 0.9 2.5 1 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2096 PF09869.4 EME27399.1 - 0.066 13.0 1.9 0.35 10.7 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Baculo_PEP_C PF04513.7 EME27399.1 - 0.078 12.7 7.1 0.25 11.1 3.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MtrG PF04210.8 EME27399.1 - 0.11 12.1 0.2 8.5 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LPP PF04728.8 EME27399.1 - 0.18 11.6 3.7 0.3 10.8 0.2 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Laminin_II PF06009.7 EME27399.1 - 0.19 11.5 6.5 0.82 9.4 4.4 2.0 1 1 0 1 1 1 0 Laminin Domain II Syntaxin-6_N PF09177.6 EME27399.1 - 0.39 11.1 8.6 0.079 13.3 2.4 2.5 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Fez1 PF06818.10 EME27399.1 - 1.1 9.2 11.4 0.14 12.1 2.9 2.4 1 1 1 2 2 2 0 Fez1 Retrotrans_gag PF03732.12 EME27399.1 - 1.1 9.3 4.6 2.4 8.2 1.2 2.9 2 1 0 2 2 2 0 Retrotransposon gag protein NPV_P10 PF05531.7 EME27399.1 - 1.3 9.3 5.5 21 5.4 1.1 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ERF PF04404.7 EME27399.1 - 1.8 8.1 11.1 1.1 8.7 0.1 2.7 2 1 1 3 3 3 0 ERF superfamily Fib_alpha PF08702.5 EME27399.1 - 5.7 7.0 7.3 66 3.6 0.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EME27399.1 - 7.9 6.0 9.9 16 5.0 6.0 2.2 1 1 0 1 1 1 0 IncA protein MMTV_SAg PF01054.12 EME27400.1 - 0.0079 15.1 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Mouse mammary tumour virus superantigen SAPS PF04499.10 EME27400.1 - 0.35 9.4 5.0 0.46 9.0 3.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMTV_SAg PF01054.12 EME27401.1 - 0.0037 16.2 0.1 0.0047 15.8 0.1 1.1 1 0 0 1 1 1 1 Mouse mammary tumour virus superantigen Mob_synth_C PF06463.8 EME27402.1 - 4.1e-35 120.2 0.0 7.5e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EME27402.1 - 1.5e-26 93.5 0.0 2.7e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EME27402.1 - 1.6e-12 47.6 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EME27402.1 - 6.4e-11 42.3 0.1 2.2e-08 34.1 0.0 3.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain ArsA_ATPase PF02374.10 EME27403.1 - 5.5e-144 478.8 0.0 2.1e-71 240.5 0.0 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EME27403.1 - 2.1e-27 95.8 0.0 1.1e-12 47.7 0.1 3.9 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME27403.1 - 1.6e-11 44.4 0.2 0.00019 21.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain SRP54 PF00448.17 EME27403.1 - 7.7e-08 32.0 0.6 0.034 13.5 0.1 4.3 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EME27403.1 - 6.4e-07 28.8 0.1 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.1 EME27403.1 - 1.6e-05 24.6 0.5 0.14 11.6 0.5 3.6 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EME27403.1 - 4.4e-05 23.0 1.4 0.0085 15.5 0.1 3.1 2 2 0 2 2 2 1 AAA-like domain ATP_bind_1 PF03029.12 EME27403.1 - 8.5e-05 22.2 2.0 0.25 10.8 0.0 2.9 3 0 0 3 3 2 2 Conserved hypothetical ATP binding protein PhoH PF02562.11 EME27403.1 - 9.4e-05 21.7 0.0 0.18 10.9 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein MobB PF03205.9 EME27403.1 - 0.00032 20.3 0.5 0.29 10.8 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B YhjQ PF06564.7 EME27403.1 - 0.00064 19.1 0.0 0.4 10.0 0.0 2.7 2 0 0 2 2 2 1 YhjQ protein ArgK PF03308.11 EME27403.1 - 0.0013 17.5 1.4 0.19 10.4 0.0 3.4 4 0 0 4 4 4 1 ArgK protein IstB_IS21 PF01695.12 EME27403.1 - 0.0014 18.0 0.0 0.18 11.2 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EME27403.1 - 0.0025 17.2 2.5 0.97 8.8 0.2 3.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EME27403.1 - 0.0028 16.5 0.9 1.4 7.6 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain PIF1 PF05970.9 EME27403.1 - 0.0088 15.0 3.2 0.56 9.0 0.0 3.5 4 0 0 4 4 4 1 PIF1-like helicase Zeta_toxin PF06414.7 EME27403.1 - 0.012 14.6 0.1 0.23 10.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ParA PF10609.4 EME27403.1 - 0.013 15.3 9.2 0.18 11.6 0.1 4.9 4 1 1 5 5 5 0 ParA/MinD ATPase like VirC1 PF07015.6 EME27403.1 - 0.016 14.3 0.0 3.3 6.7 0.0 2.9 3 0 0 3 3 3 0 VirC1 protein AAA_17 PF13207.1 EME27403.1 - 0.021 15.6 2.4 7.4 7.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EME27403.1 - 0.033 14.4 2.5 2.3 8.5 0.0 3.9 4 1 1 5 5 4 0 AAA domain AAA_30 PF13604.1 EME27403.1 - 0.038 13.5 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3094 PF11293.3 EME27403.1 - 0.065 12.7 0.0 0.64 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) KaiC PF06745.8 EME27403.1 - 0.14 11.2 2.3 0.38 9.8 0.0 2.8 4 0 0 4 4 4 0 KaiC AAA_22 PF13401.1 EME27403.1 - 1.3 9.2 4.6 2.3 8.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain Miro PF08477.8 EME27403.1 - 3.4 8.1 5.8 32 5.0 0.1 3.4 3 0 0 3 3 3 0 Miro-like protein RINT1_TIP1 PF04437.8 EME27404.1 - 1.6e-38 132.5 12.4 2.1e-38 132.1 6.4 2.5 2 1 0 2 2 2 1 RINT-1 / TIP-1 family BcrAD_BadFG PF01869.15 EME27404.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Dynamin_M PF01031.15 EME27404.1 - 0.14 10.8 4.6 0.48 9.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin central region DUF3347 PF11827.3 EME27404.1 - 4.2 7.3 6.2 1.7 8.5 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) DUF2505 PF10698.4 EME27405.1 - 0.015 14.7 0.0 0.059 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) ORMDL PF04061.9 EME27406.1 - 4.7e-35 120.1 8.2 5.3e-35 119.9 5.7 1.0 1 0 0 1 1 1 1 ORMDL family DUF4181 PF13789.1 EME27406.1 - 4.8 7.1 9.0 1.8 8.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) SNase PF00565.12 EME27407.1 - 1.3e-50 170.1 0.1 6.5e-09 36.0 0.0 5.2 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EME27407.1 - 7.4e-15 54.8 0.0 1.5e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EME27407.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) EamA PF00892.15 EME27408.1 - 5.2e-08 32.9 4.8 5.2e-08 32.9 3.4 3.5 2 2 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EME27408.1 - 2.9e-06 26.3 24.2 1.1e-05 24.4 16.8 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EME27408.1 - 5.8e-06 25.4 18.5 9.6e-06 24.7 12.8 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EME27408.1 - 7.6e-06 25.2 2.7 1.5e-05 24.2 1.9 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EME27408.1 - 0.0057 16.8 7.2 0.0057 16.8 5.0 3.0 2 2 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EME27408.1 - 0.045 13.4 30.5 0.071 12.7 5.2 2.8 2 1 1 3 3 3 0 Triose-phosphate Transporter family EamA PF00892.15 EME27409.1 - 5.3e-05 23.2 3.5 5.3e-05 23.2 2.4 3.5 2 2 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EME27409.1 - 0.00028 19.8 23.7 0.0011 17.9 16.4 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) MCD PF05292.6 EME27410.1 - 9.8e-18 63.9 0.0 4.4e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase (MCD) RasGAP_C PF03836.10 EME27410.1 - 0.049 13.3 0.3 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Sialidase PF02973.11 EME27410.1 - 0.07 12.0 0.6 0.12 11.3 0.4 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain DUF436 PF04260.7 EME27410.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) MCD PF05292.6 EME27411.1 - 2.4e-20 72.5 0.0 1.9e-19 69.5 0.0 2.2 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) Pyrophosphatase PF00719.14 EME27413.1 - 2.9e-49 166.4 0.0 3.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MoCF_biosynth PF00994.19 EME27414.1 - 5.3e-26 90.7 0.0 9.5e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.14 EME27414.1 - 6.6e-26 91.1 0.0 1.4e-17 64.0 0.0 2.4 1 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family SRP14 PF02290.10 EME27415.1 - 5.6e-13 48.6 1.9 1.1e-12 47.7 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle 14kD protein V-ATPase_H_C PF11698.3 EME27415.1 - 0.07 13.0 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H PPR_3 PF13812.1 EME27417.1 - 0.069 13.4 0.3 48 4.5 0.0 4.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 EME27417.1 - 2.1 8.5 7.3 29 4.9 0.0 5.5 7 0 0 7 7 7 0 PPR repeat SNF2_N PF00176.18 EME27418.1 - 4.4e-78 262.1 0.4 4.4e-78 262.1 0.2 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME27418.1 - 1.7e-17 63.0 0.0 7.8e-17 60.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EME27418.1 - 1.3e-08 34.5 17.5 7.6e-08 32.0 12.1 2.5 1 0 0 1 1 1 1 HSA SnAC PF14619.1 EME27418.1 - 2.6e-08 33.9 3.9 2.6e-08 33.9 2.7 4.6 6 1 0 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.24 EME27418.1 - 7.9e-06 25.4 0.0 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase QLQ PF08880.6 EME27418.1 - 0.0009 18.5 0.9 0.002 17.4 0.6 1.5 1 0 0 1 1 1 1 QLQ TFIID_30kDa PF03540.8 EME27418.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit UDPG_MGDP_dh_N PF03721.9 EME27419.1 - 6.5e-49 165.8 0.0 6.3e-45 152.8 0.0 2.3 2 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EME27419.1 - 1.4e-35 121.6 0.0 3.8e-33 113.8 0.0 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EME27419.1 - 6.8e-29 99.9 0.0 2.2e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EME27419.1 - 0.042 13.5 0.0 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EME27419.1 - 0.079 13.3 0.0 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EME27419.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME27420.1 - 5e-54 182.4 0.0 8.8e-54 181.6 0.0 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EME27420.1 - 1.3e-35 121.7 0.0 3.6e-33 113.9 0.0 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EME27420.1 - 6.2e-29 100.0 0.0 2.1e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EME27420.1 - 0.041 13.6 0.0 0.9 9.2 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EME27420.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase zf-RING_2 PF13639.1 EME27421.1 - 1.4e-09 37.5 9.2 3.9e-09 36.1 6.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EME27421.1 - 6.9e-09 35.4 11.4 1.8e-08 34.1 7.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EME27421.1 - 6.5e-08 32.1 5.3 1.4e-07 31.0 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME27421.1 - 2.9e-07 30.0 8.3 2.9e-07 30.0 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME27421.1 - 3.2e-07 30.2 10.0 3.2e-07 30.2 7.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27421.1 - 2.3e-06 27.2 8.9 1.2e-05 24.8 6.1 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME27421.1 - 6.5e-06 25.7 4.1 6.8e-06 25.7 1.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EME27421.1 - 0.00067 19.3 3.1 0.0016 18.2 2.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EME27421.1 - 0.0025 17.3 6.1 0.0056 16.1 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EME27421.1 - 0.014 14.9 3.0 0.031 13.8 1.0 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EME27421.1 - 0.042 13.7 3.1 0.095 12.5 2.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EME27421.1 - 0.094 12.8 4.9 0.43 10.7 3.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger DUF340 PF03956.8 EME27422.1 - 0.0026 17.0 1.1 0.016 14.5 0.7 2.0 2 0 0 2 2 2 1 Membrane protein of unknown function (DUF340) CorA PF01544.13 EME27422.1 - 0.14 11.1 14.0 0.26 10.2 5.9 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Cullin PF00888.17 EME27423.1 - 5.6e-156 520.4 14.6 7.8e-156 520.0 10.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME27423.1 - 3.4e-28 97.2 3.5 3.6e-28 97.1 0.7 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_IclR PF09339.5 EME27423.1 - 0.001 18.6 0.0 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.1 EME27423.1 - 0.0067 15.7 1.1 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.11 EME27423.1 - 0.019 15.0 0.1 0.094 12.8 0.0 2.4 2 0 0 2 2 2 0 Penicillinase repressor AP_endonuc_2 PF01261.19 EME27423.1 - 0.085 12.1 0.0 7.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel HTH_27 PF13463.1 EME27423.1 - 0.092 13.0 0.0 6.9 7.0 0.0 3.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain CDP-OH_P_transf PF01066.16 EME27424.1 - 9.1e-14 51.5 1.2 9.1e-14 51.5 0.9 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.16 EME27425.1 - 4.9e-18 65.2 4.6 4.9e-18 65.2 3.2 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fascin PF06268.8 EME27426.1 - 1.8e-08 34.4 1.5 0.00035 20.6 0.1 4.1 3 2 2 5 5 5 2 Fascin domain Polyketide_cyc PF03364.15 EME27426.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EME27426.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport 7TM_transglut PF14402.1 EME27427.1 - 4.4 6.1 5.1 7.9 5.3 3.5 1.3 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase SANTA PF09133.5 EME27428.1 - 3.7e-09 36.4 0.4 6.2e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 SANTA (SANT Associated) Ras PF00071.17 EME27429.1 - 1.9e-56 189.8 0.0 2.3e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME27429.1 - 1.5e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME27429.1 - 1.5e-14 53.6 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME27429.1 - 1.9e-06 27.2 0.0 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME27429.1 - 3.8e-06 26.8 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME27429.1 - 5e-05 22.8 0.0 0.004 16.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 EME27429.1 - 0.00048 19.8 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME27429.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME27429.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EME27429.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EME27429.1 - 0.0027 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EME27429.1 - 0.0032 17.1 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase PRK PF00485.13 EME27429.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 EME27429.1 - 0.0097 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 EME27429.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ATP_bind_1 PF03029.12 EME27429.1 - 0.018 14.5 0.0 3.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EME27429.1 - 0.043 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EME27429.1 - 0.056 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 EME27429.1 - 0.06 12.8 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EME27429.1 - 0.061 13.6 0.0 0.08 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EME27429.1 - 0.096 11.6 0.0 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 Septin cobW PF02492.14 EME27429.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EME27429.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EME27429.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cornichon PF03311.9 EME27430.1 - 6.4e-39 133.0 7.4 7.5e-39 132.7 5.2 1.1 1 0 0 1 1 1 1 Cornichon protein UQ_con PF00179.21 EME27431.1 - 2.6e-47 159.7 0.0 3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME27431.1 - 1.2e-06 28.2 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME27431.1 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EME27431.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.21 EME27432.1 - 2.6e-47 159.7 0.0 3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME27432.1 - 1.2e-06 28.2 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME27432.1 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EME27432.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain CHCH PF06747.8 EME27433.1 - 0.00068 19.4 3.4 0.12 12.3 0.0 3.1 1 1 2 3 3 3 3 CHCH domain Metallophos PF00149.23 EME27434.1 - 5.7e-45 153.1 0.2 7.1e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 EME27435.1 - 0.0001 21.9 0.2 0.00029 20.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME27435.1 - 0.056 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain MAGE PF01454.14 EME27436.1 - 1.1e-25 90.1 0.0 1.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 MAGE family Pkinase PF00069.20 EME27438.1 - 5.7e-82 274.7 0.0 7.4e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27438.1 - 4.2e-42 143.9 0.0 6.3e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EME27438.1 - 7.3e-06 26.1 0.4 1.7e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EME27438.1 - 3.6e-05 22.8 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EME27438.1 - 0.00039 19.5 0.0 0.00095 18.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.1 EME27438.1 - 0.00093 19.2 0.1 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EME27438.1 - 0.00099 18.8 0.0 0.042 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME27438.1 - 0.012 15.0 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_L28 PF00830.14 EME27439.1 - 5.8e-11 42.0 0.0 8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Ribosomal_L28 PF00830.14 EME27440.1 - 5.8e-11 42.0 0.0 8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28 family V-ATPase_G PF03179.10 EME27441.1 - 5.8e-27 94.0 14.6 6.4e-27 93.9 10.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EME27441.1 - 0.00032 19.9 19.2 0.00046 19.4 13.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF3584 PF12128.3 EME27441.1 - 0.021 12.1 11.3 0.024 12.0 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIVA PF05103.8 EME27441.1 - 0.036 14.1 15.9 0.02 14.9 6.5 2.3 2 0 0 2 2 2 0 DivIVA protein DUF4473 PF14747.1 EME27441.1 - 0.044 14.0 6.3 1 9.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF3781 PF12636.2 EME27441.1 - 0.046 13.6 0.1 0.086 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Apolipoprotein PF01442.13 EME27441.1 - 0.069 12.6 13.8 0.078 12.4 3.1 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF600 PF04634.7 EME27441.1 - 0.12 12.4 2.6 0.13 12.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF600 ATP-synt_B PF00430.13 EME27441.1 - 0.13 12.0 18.7 0.84 9.4 12.9 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF262 PF03235.9 EME27441.1 - 0.19 11.7 8.7 0.22 11.4 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 Ndc80_HEC PF03801.8 EME27441.1 - 0.2 11.0 2.4 0.28 10.6 1.7 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family DUF826 PF05696.6 EME27441.1 - 0.37 10.9 8.4 5.6 7.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF826) DALR_1 PF05746.10 EME27441.1 - 0.46 10.4 5.8 0.58 10.1 1.8 2.0 1 1 1 2 2 2 0 DALR anticodon binding domain ArgK PF03308.11 EME27441.1 - 0.57 8.8 2.3 0.67 8.6 1.6 1.1 1 0 0 1 1 1 0 ArgK protein Prismane PF03063.15 EME27441.1 - 0.7 8.2 3.8 0.85 7.9 2.6 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family ApoO PF09769.4 EME27441.1 - 0.77 9.4 5.1 1.2 8.8 3.6 1.4 1 1 0 1 1 1 0 Apolipoprotein O DUF883 PF05957.8 EME27441.1 - 0.97 9.8 11.8 2.3 8.6 1.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Paramyxo_ncap PF00973.14 EME27441.1 - 1.1 7.8 6.9 1.1 7.8 4.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Inhibitor_I29 PF08246.7 EME27441.1 - 1.3 9.3 5.8 1.1 9.6 0.2 2.2 1 1 1 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) PV-1 PF06637.6 EME27441.1 - 1.5 7.3 12.7 1.7 7.1 8.8 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Tho2 PF11262.3 EME27441.1 - 1.6 7.6 9.0 2 7.3 6.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.10 EME27441.1 - 1.6 7.8 11.5 1.9 7.5 8.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit RolB_RolC PF02027.12 EME27441.1 - 2 7.5 5.3 2.5 7.2 3.6 1.3 1 1 0 1 1 1 0 RolB/RolC glucosidase family Mnd1 PF03962.10 EME27441.1 - 2.3 7.8 15.2 2.8 7.5 10.6 1.1 1 0 0 1 1 1 0 Mnd1 family GrpE PF01025.14 EME27441.1 - 2.5 7.6 17.8 11 5.5 12.3 1.8 1 1 0 1 1 1 0 GrpE SBP_bac_7 PF03480.8 EME27441.1 - 3 6.8 12.4 1.5 7.9 0.2 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Prominin PF05478.6 EME27441.1 - 3.1 5.2 5.8 4.9 4.5 1.0 1.5 1 1 1 2 2 2 0 Prominin HBS1_N PF08938.5 EME27441.1 - 3.5 7.8 6.8 31 4.7 4.7 2.1 1 1 0 1 1 1 0 HBS1 N-terminus TipAS PF07739.8 EME27441.1 - 6.2 7.1 11.7 0.52 10.6 2.4 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Spore_coat_CotO PF14153.1 EME27441.1 - 6.9 6.0 16.0 8.4 5.7 11.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AAA_11 PF13086.1 EME27441.1 - 7.5 6.0 7.9 8.8 5.8 5.4 1.1 1 0 0 1 1 1 0 AAA domain RRF PF01765.14 EME27441.1 - 8.3 5.8 12.7 9.2 5.7 8.4 1.4 1 1 0 1 1 1 0 Ribosome recycling factor vATP-synt_E PF01991.13 EME27441.1 - 9.8 5.3 17.8 17 4.6 12.4 1.4 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit TMF_TATA_bd PF12325.3 EME27442.1 - 3e-19 68.9 7.6 3e-19 68.9 5.3 7.3 2 1 5 8 8 8 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EME27442.1 - 1.1e-12 47.5 20.8 1.1e-12 47.5 14.4 9.3 6 4 3 9 9 9 2 TATA element modulatory factor 1 DNA binding AAA_27 PF13514.1 EME27442.1 - 8.8e-06 23.7 68.2 0.00036 18.4 40.2 2.3 2 0 0 2 2 2 2 AAA domain Tropomyosin_1 PF12718.2 EME27442.1 - 0.00034 20.4 19.4 0.00034 20.4 13.5 6.6 3 1 3 6 6 6 2 Tropomyosin like Fib_alpha PF08702.5 EME27442.1 - 0.011 15.8 14.0 0.011 15.8 9.7 5.6 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EME27442.1 - 0.4 10.2 120.3 0.37 10.3 7.7 5.5 2 1 3 5 5 5 0 IncA protein Mnd1 PF03962.10 EME27442.1 - 0.73 9.4 85.8 1.2 8.7 7.3 5.5 2 1 3 5 5 5 0 Mnd1 family DUF3584 PF12128.3 EME27442.1 - 2.3 5.4 94.3 1 6.6 4.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EME27442.1 - 5.2 6.1 27.4 0.93 8.6 0.9 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 EME27442.1 - 7.7 5.8 93.8 0.037 13.5 15.2 5.9 1 1 3 6 6 6 0 Intermediate filament protein IGR PF09597.5 EME27443.1 - 6.9e-08 32.2 0.0 9.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 EME27443.1 - 4.7e-05 23.4 0.0 8.4e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EME27443.1 - 0.034 13.9 0.0 0.091 12.6 0.0 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) IF4E PF01652.13 EME27444.1 - 4.6e-49 166.1 0.1 5.7e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CLTH PF10607.4 EME27445.1 - 4.8e-26 91.1 1.1 8.8e-26 90.3 0.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EME27445.1 - 4.1e-15 55.2 2.2 4.1e-15 55.2 1.5 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.1 EME27445.1 - 3.3e-06 26.7 1.0 3.3e-06 26.7 0.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME27445.1 - 3.7e-05 23.3 1.0 3.7e-05 23.3 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME27445.1 - 0.00012 21.9 1.1 0.00012 21.9 0.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME27445.1 - 0.00037 20.2 2.7 0.00037 20.2 1.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EME27445.1 - 0.0008 19.2 2.5 0.003 17.3 1.7 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EME27445.1 - 0.0013 18.3 2.1 0.0013 18.3 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DDE_Tnp_IS66 PF03050.9 EME27445.1 - 0.042 13.0 4.0 2.5 7.2 2.4 2.1 2 0 0 2 2 2 0 Transposase IS66 family EzrA PF06160.7 EME27445.1 - 0.23 9.6 7.0 0.4 8.8 4.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Perilipin PF03036.11 EME27445.1 - 0.43 9.3 3.4 0.59 8.9 2.4 1.1 1 0 0 1 1 1 0 Perilipin family TFIID_90kDa PF04494.10 EME27445.1 - 1.1 9.3 6.1 0.22 11.6 0.2 2.5 2 2 1 3 3 3 0 WD40 associated region in TFIID subunit Hexapep PF00132.19 EME27446.1 - 3.3e-10 38.9 7.2 2.4e-05 23.6 0.2 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME27446.1 - 0.017 14.6 2.5 5.2 6.7 0.0 3.7 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase RRM_1 PF00076.17 EME27447.1 - 1.6e-17 62.9 0.0 2.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27447.1 - 2.8e-09 36.8 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27447.1 - 6.5e-09 35.5 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME27447.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.17 EME27448.1 - 1.3e-17 63.1 0.0 2.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27448.1 - 2.3e-09 37.0 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27448.1 - 5.6e-09 35.7 0.0 7.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME27448.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif adh_short PF00106.20 EME27449.1 - 1.6e-21 76.9 0.0 3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME27449.1 - 3.9e-11 42.9 0.0 4.8e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME27449.1 - 4.5e-05 23.0 0.0 8.9e-05 22.0 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME27449.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME27449.1 - 0.019 14.9 0.2 0.045 13.7 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME27449.1 - 0.059 12.2 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Formyl_trans_N PF00551.14 EME27450.1 - 9.1e-38 129.6 0.0 1.3e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EME27450.1 - 7.8e-07 29.1 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain PSII_BNR PF14870.1 EME27451.1 - 2.3e-117 391.3 0.3 2.8e-117 391.0 0.2 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EME27451.1 - 4.9e-06 25.5 10.6 0.34 10.9 0.1 5.1 5 0 0 5 5 5 3 BNR/Asp-box repeat DUF972 PF06156.8 EME27452.1 - 0.02 15.2 2.3 0.19 12.0 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF4265 PF14085.1 EME27452.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Kri1_C PF12936.2 EME27453.1 - 2e-19 69.3 0.2 2e-19 69.3 0.1 3.3 2 1 0 2 2 2 1 KRI1-like family C-terminal TPR_14 PF13428.1 EME27454.1 - 5.4e-27 91.8 4.0 5.6e-05 23.4 0.1 8.8 2 1 7 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME27454.1 - 1.1e-26 92.8 1.0 1.8e-06 28.4 0.1 5.6 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 EME27454.1 - 1.2e-26 92.1 6.6 3.3e-08 33.0 0.7 6.0 3 2 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 EME27454.1 - 6.8e-25 84.9 12.7 0.0016 18.1 0.7 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 EME27454.1 - 8.7e-25 84.8 13.3 3.8e-05 23.5 0.0 9.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME27454.1 - 8.9e-22 77.2 0.4 7.7e-05 22.9 0.2 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME27454.1 - 5.1e-20 69.6 6.5 0.00048 19.7 0.3 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME27454.1 - 4.4e-14 52.1 13.3 1.6e-05 24.7 0.1 6.8 3 1 5 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME27454.1 - 1.2e-13 50.0 11.6 0.0029 17.1 1.1 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME27454.1 - 3.9e-11 41.8 2.8 1.4 8.9 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME27454.1 - 4.1e-11 42.4 7.2 1.2e-05 24.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Suf PF05843.9 EME27454.1 - 2.3e-08 34.1 2.1 3.7e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_9 PF13371.1 EME27454.1 - 7.3e-07 28.9 0.6 0.33 10.8 0.2 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 EME27454.1 - 4e-06 25.8 0.3 0.0084 14.9 0.1 3.2 1 1 2 3 3 3 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EME27454.1 - 0.0084 16.5 9.4 28 5.4 0.0 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EME27454.1 - 0.035 13.8 5.7 27 4.5 0.0 5.3 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 MIT PF04212.13 EME27454.1 - 0.064 13.1 7.0 8.4 6.3 1.1 4.9 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EME27454.1 - 3.6 8.2 5.1 13 6.6 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat CLTH PF10607.4 EME27455.1 - 1.8e-08 34.2 8.2 3.4e-05 23.5 0.5 3.9 3 1 0 3 3 3 2 CTLH/CRA C-terminal to LisH motif domain UBA PF00627.26 EME27455.1 - 0.076 12.8 0.0 0.076 12.8 0.0 3.1 4 0 0 4 4 4 0 UBA/TS-N domain CLTH PF10607.4 EME27456.1 - 1.4e-05 24.7 0.8 1.4e-05 24.7 0.5 2.6 3 1 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain UBA PF00627.26 EME27456.1 - 0.015 15.0 2.1 0.042 13.7 0.0 3.0 3 0 0 3 3 3 0 UBA/TS-N domain SGS PF05002.10 EME27457.1 - 2.7e-20 71.8 3.3 8.8e-20 70.2 2.3 1.9 1 1 0 1 1 1 1 SGS domain CS PF04969.11 EME27457.1 - 3.1e-12 46.8 0.7 5.3e-12 46.1 0.5 1.4 1 0 0 1 1 1 1 CS domain peroxidase PF00141.18 EME27458.1 - 6.5e-37 127.2 0.0 1.6e-36 125.9 0.0 1.6 1 1 0 1 1 1 1 Peroxidase peroxidase PF00141.18 EME27459.1 - 2.8e-35 121.8 0.0 5.7e-35 120.8 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Ank_2 PF12796.2 EME27462.1 - 9.6e-37 125.2 0.2 2e-23 82.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME27462.1 - 4e-29 98.9 0.2 3.9e-12 45.3 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EME27462.1 - 6.7e-28 96.5 2.7 2.2e-11 43.9 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME27462.1 - 7.4e-21 73.7 1.9 3.4e-10 39.8 0.1 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME27462.1 - 3.6e-20 70.0 0.0 4.1e-07 29.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat IncA PF04156.9 EME27463.1 - 0.0066 16.0 1.1 0.0066 16.0 0.7 2.5 1 1 2 3 3 3 1 IncA protein PHTB1_N PF14727.1 EME27463.1 - 0.024 13.6 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 PTHB1 N-terminus Acetyltransf_11 PF13720.1 EME27463.1 - 0.044 14.0 1.7 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Exo_endo_phos PF03372.18 EME27464.1 - 2.5e-24 86.5 0.0 3.1e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME27464.1 - 8.7e-10 38.2 0.0 2.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Asn_synthase PF00733.16 EME27465.1 - 2.6e-25 89.3 0.0 8.2e-24 84.4 0.0 2.0 1 1 0 1 1 1 1 Asparagine synthase GCS PF03074.11 EME27466.1 - 5.1e-146 486.4 1.1 2.2e-145 484.4 0.8 1.8 1 1 0 1 1 1 1 Glutamate-cysteine ligase S1 PF00575.18 EME27466.1 - 0.018 15.1 0.1 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 S1 RNA binding domain FMO-like PF00743.14 EME27469.1 - 6.6e-55 186.3 0.0 3.9e-41 140.8 0.1 2.0 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME27469.1 - 6e-22 78.7 0.0 2.3e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME27469.1 - 3.1e-10 40.3 0.1 4e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME27469.1 - 1e-09 37.7 0.0 3.2e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME27469.1 - 2.5e-09 37.1 0.1 1e-06 28.6 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME27469.1 - 2.1e-07 30.8 0.1 3.1e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME27469.1 - 1.1e-06 28.6 0.0 1.6e-05 24.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME27469.1 - 6.5e-06 25.4 0.0 0.023 13.7 0.1 2.2 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EME27469.1 - 0.00025 20.0 0.4 0.2 10.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 EME27469.1 - 0.00026 19.5 1.5 0.0032 16.0 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.11 EME27469.1 - 0.00032 20.1 0.3 0.054 12.9 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EME27469.1 - 0.00042 20.0 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EME27469.1 - 0.00099 18.0 0.2 0.0018 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME27469.1 - 0.0016 17.4 0.0 0.56 9.0 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase IlvN PF07991.7 EME27469.1 - 0.0016 17.8 0.0 0.0095 15.3 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EME27469.1 - 0.0068 16.2 0.3 0.12 12.1 0.1 2.3 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EME27469.1 - 0.028 14.5 0.0 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EME27469.1 - 0.078 11.8 0.0 0.6 8.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EME27469.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EME27469.1 - 0.12 11.9 0.0 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EME27469.1 - 0.13 11.2 0.1 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Malic_M PF03949.10 EME27469.1 - 0.16 11.4 0.1 8.8 5.7 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Kin17_mid PF10357.4 EME27470.1 - 1.9e-45 153.6 0.5 3.6e-45 152.7 0.3 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EME27470.1 - 0.0008 19.5 5.9 0.0017 18.4 4.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type KOW PF00467.24 EME27470.1 - 0.0016 18.1 0.2 0.022 14.5 0.0 2.7 3 0 0 3 3 3 1 KOW motif zf-C2H2_jaz PF12171.3 EME27470.1 - 0.0038 17.3 6.0 0.0038 17.3 4.2 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME27470.1 - 0.023 14.8 0.9 0.055 13.5 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DZR PF12773.2 EME27471.1 - 0.0022 17.7 1.3 0.0022 17.7 0.9 2.6 2 0 0 2 2 2 1 Double zinc ribbon UPF0547 PF10571.4 EME27471.1 - 0.0035 16.9 1.5 0.0035 16.9 1.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-FCS PF06467.9 EME27471.1 - 0.043 13.4 15.4 0.88 9.2 0.1 3.8 2 2 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.1 EME27471.1 - 0.14 11.6 9.0 0.059 12.8 1.7 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Med27 PF11571.3 EME27471.1 - 0.29 11.2 6.2 1.5 9.0 0.1 2.7 2 2 0 2 2 2 0 Mediator complex subunit 27 zf-ribbon_3 PF13248.1 EME27471.1 - 4.7 6.5 9.3 0.39 10.0 0.7 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-DHHC PF01529.15 EME27471.1 - 5.2 6.4 9.6 6.8 6.0 6.4 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase DnaJ PF00226.26 EME27472.1 - 1.5e-22 79.0 0.5 3.3e-22 77.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.19 EME27474.1 - 9.5e-54 182.1 0.0 1.3e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EME27474.1 - 2.7e-31 107.7 0.0 4.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF812 PF05667.6 EME27475.1 - 0.01 14.3 0.7 0.011 14.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DASH_Dad2 PF08654.5 EME27475.1 - 0.066 13.2 2.2 0.089 12.8 1.4 1.3 1 1 0 1 1 1 0 DASH complex subunit Dad2 ETS_PEA3_N PF04621.8 EME27475.1 - 0.11 11.7 0.5 0.13 11.4 0.4 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Rhomboid PF01694.17 EME27476.1 - 2e-10 40.8 11.2 4.6e-10 39.7 7.8 1.6 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 EME27476.1 - 0.0034 16.9 5.8 0.016 14.7 4.0 1.9 1 1 0 1 1 1 1 Der1-like family PPR_2 PF13041.1 EME27477.1 - 0.00064 19.6 0.4 0.22 11.5 0.0 4.2 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 EME27477.1 - 0.02 14.8 5.4 20 5.4 0.0 5.0 5 0 0 5 5 5 0 PPR repeat WD40 PF00400.27 EME27478.1 - 3.9e-11 42.3 3.3 7.6e-05 22.4 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Ribosomal_60s PF00428.14 EME27479.1 - 3.4e-24 85.0 10.4 4.3e-24 84.7 7.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 EME27479.1 - 1.3 9.0 5.3 5.3 7.0 2.5 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pribosyltran PF00156.22 EME27480.1 - 3.6e-18 65.4 0.0 5.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME27480.1 - 0.0012 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EME27480.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase TPT PF03151.11 EME27481.1 - 0.0007 19.2 6.7 0.0007 19.2 4.7 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family eIF-5_eIF-2B PF01873.12 EME27482.1 - 4.2e-37 126.5 0.6 7.1e-37 125.8 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EME27482.1 - 4.5e-15 55.3 2.6 4.5e-15 55.3 1.8 3.4 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Ribosomal_S19 PF00203.16 EME27483.1 - 5.2e-33 112.5 0.6 7.6e-33 111.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 RIB43A PF05914.7 EME27483.1 - 0.0061 15.2 0.4 0.007 15.0 0.3 1.0 1 0 0 1 1 1 1 RIB43A DUF3619 PF12279.3 EME27483.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Ras PF00071.17 EME27484.1 - 2.2e-41 140.9 0.0 2.6e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME27484.1 - 4.6e-13 49.7 0.0 6.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME27484.1 - 8.1e-06 25.1 0.0 9.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EME27484.1 - 9.6e-06 24.9 0.0 0.00029 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EME27484.1 - 5.8e-05 22.6 0.0 9.1e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EME27484.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EME27484.1 - 0.0077 16.1 0.0 0.0095 15.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EME27484.1 - 0.013 16.3 0.0 0.15 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME27484.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EME27484.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 EME27484.1 - 0.029 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME27484.1 - 0.11 12.6 0.0 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EME27484.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EME27484.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain ORC4_C PF14629.1 EME27485.1 - 3.1e-12 46.3 0.8 5.5e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus T2SE PF00437.15 EME27485.1 - 0.005 15.7 0.1 0.0093 14.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EME27485.1 - 0.0073 16.3 0.1 0.047 13.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.13 EME27485.1 - 0.017 14.7 0.4 0.017 14.7 0.2 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein ORC4_C PF14629.1 EME27486.1 - 2.8e-16 59.5 1.2 4.5e-16 58.8 0.8 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus T2SE PF00437.15 EME27486.1 - 0.0052 15.7 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EME27486.1 - 0.0077 16.2 0.2 0.028 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.13 EME27486.1 - 0.019 14.6 0.4 0.019 14.6 0.2 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein NAD_binding_10 PF13460.1 EME27487.1 - 1.4e-28 100.1 0.1 1.8e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME27487.1 - 2.9e-13 49.7 0.1 5.5e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME27487.1 - 8.2e-13 48.1 0.2 3.5e-12 46.0 0.2 1.9 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EME27487.1 - 2.4e-11 42.8 0.0 3.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EME27487.1 - 2e-06 27.8 1.7 4.7e-05 23.3 1.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME27487.1 - 9.9e-06 24.6 0.1 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME27487.1 - 0.0011 17.9 0.2 0.0025 16.7 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EME27487.1 - 0.0019 17.8 1.2 0.011 15.4 0.8 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EME27487.1 - 0.017 14.0 2.4 0.56 9.0 0.9 2.7 2 1 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.19 EME27487.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DSPc PF00782.15 EME27488.1 - 2.7e-25 88.4 0.0 1.3e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EME27488.1 - 8.2e-09 35.8 0.0 8.1e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EME27488.1 - 0.0025 17.2 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EME27488.1 - 0.0037 16.7 0.1 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF1363 PF07101.6 EME27488.1 - 0.027 14.5 0.5 0.058 13.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) DJ-1_PfpI PF01965.19 EME27489.1 - 7.9e-32 109.7 0.2 9.3e-32 109.5 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EME27489.1 - 4e-13 48.9 0.1 4.7e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 Putative amidotransferase DUF2493 PF10686.4 EME27489.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) AAA PF00004.24 EME27490.1 - 2.5e-36 124.7 0.0 6.9e-36 123.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME27490.1 - 2.4e-07 30.9 0.0 0.00017 21.6 0.0 3.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EME27490.1 - 1.3e-05 24.9 0.0 6.8e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME27490.1 - 2.5e-05 23.7 1.1 0.044 13.1 0.3 2.8 1 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EME27490.1 - 3.8e-05 23.7 6.7 0.0003 20.8 0.1 3.7 3 2 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.7 EME27490.1 - 7.1e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME27490.1 - 0.00012 22.9 0.1 0.0024 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EME27490.1 - 0.00019 20.4 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EME27490.1 - 0.00022 21.1 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EME27490.1 - 0.00025 20.7 0.6 0.019 14.5 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EME27490.1 - 0.00028 20.5 0.0 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME27490.1 - 0.00053 19.8 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EME27490.1 - 0.00057 19.5 0.1 0.0025 17.5 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EME27490.1 - 0.0011 19.2 0.1 0.012 15.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EME27490.1 - 0.0016 17.2 0.0 0.0046 15.7 0.0 1.7 1 1 1 2 2 2 1 TIP49 C-terminus UPF0079 PF02367.12 EME27490.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EME27490.1 - 0.0025 17.9 0.0 0.0096 16.0 0.0 2.1 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.12 EME27490.1 - 0.0032 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EME27490.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EME27490.1 - 0.004 16.8 0.7 0.24 11.0 0.0 3.1 2 1 1 3 3 3 1 NACHT domain AAA_2 PF07724.9 EME27490.1 - 0.0083 16.0 0.0 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EME27490.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EME27490.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EME27490.1 - 0.016 15.1 0.2 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EME27490.1 - 0.018 14.2 0.1 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EME27490.1 - 0.022 15.0 0.3 0.071 13.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 EME27490.1 - 0.033 13.0 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EME27490.1 - 0.035 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EME27490.1 - 0.04 13.6 0.1 1.2 8.7 0.0 2.6 1 1 1 2 2 2 0 Archaeal ATPase KaiC PF06745.8 EME27490.1 - 0.073 12.1 0.3 1.2 8.2 0.0 2.6 2 1 1 3 3 3 0 KaiC DivIC PF04977.10 EME27490.1 - 0.51 9.8 4.8 0.11 12.0 0.4 2.1 2 0 0 2 2 2 0 Septum formation initiator Peptidase_C26 PF07722.8 EME27491.1 - 1.6e-43 148.6 0.0 7.7e-42 143.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EME27491.1 - 4.9e-10 39.1 0.0 2.5e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Pkinase PF00069.20 EME27492.1 - 8.9e-79 264.3 0.0 8.4e-66 221.7 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME27492.1 - 1.1e-78 263.8 0.0 3.4e-67 226.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase ANTH PF07651.11 EME27492.1 - 5.9e-10 38.3 0.0 1.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 ANTH domain Kinase-like PF14531.1 EME27492.1 - 7.7e-09 34.9 0.0 2.7e-05 23.3 0.0 3.0 2 1 0 2 2 2 2 Kinase-like UBA PF00627.26 EME27492.1 - 5.1e-06 26.1 0.2 1.4e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain NMD3 PF04981.8 EME27493.1 - 2.5e-73 246.0 1.9 3.7e-73 245.5 1.3 1.3 1 0 0 1 1 1 1 NMD3 family SRP9-21 PF05486.7 EME27493.1 - 0.076 12.7 0.1 0.46 10.2 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Asparaginase_2 PF01112.13 EME27494.1 - 3.4e-61 206.7 0.0 5.3e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase CN_hydrolase PF00795.17 EME27494.1 - 1.9e-12 46.9 0.0 3.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase K-cyclin_vir_C PF09080.5 EME27494.1 - 0.023 14.8 0.1 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 K cyclin, C terminal Diphthamide_syn PF01866.12 EME27494.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Asparaginase_2 PF01112.13 EME27495.1 - 4.8e-66 222.6 0.2 7.1e-66 222.1 0.1 1.1 1 0 0 1 1 1 1 Asparaginase K-cyclin_vir_C PF09080.5 EME27495.1 - 0.015 15.4 0.1 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 K cyclin, C terminal SWIB PF02201.13 EME27497.1 - 1.1e-09 37.7 0.0 4e-09 36.0 0.0 2.0 1 1 1 2 2 2 1 SWIB/MDM2 domain DIM1 PF02966.11 EME27497.1 - 0.037 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 CLASP_N PF12348.3 EME27498.1 - 6e-15 55.2 1.9 1.5e-13 50.6 1.3 2.5 1 1 0 1 1 1 1 CLASP N terminal Sugar_tr PF00083.19 EME27499.1 - 1.9e-89 300.3 30.4 2.9e-89 299.7 21.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27499.1 - 1.5e-30 106.0 29.1 1.5e-30 106.0 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME27499.1 - 2.4e-06 26.0 11.1 3.4e-06 25.5 3.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EME27499.1 - 0.017 14.8 8.5 0.53 10.1 0.3 4.0 3 0 0 3 3 3 0 MFS_1 like family DUF1228 PF06779.9 EME27499.1 - 0.025 14.5 7.2 0.47 10.5 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) TPR_14 PF13428.1 EME27500.1 - 1.1e-13 50.4 10.8 0.57 10.9 0.0 9.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME27500.1 - 1.7e-13 50.3 12.8 0.00066 19.5 0.1 6.1 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME27500.1 - 1.3e-09 37.1 5.9 0.04 13.7 0.3 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME27500.1 - 2.8e-08 33.9 3.1 4.1 7.8 0.0 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat NRDE-2 PF08424.5 EME27500.1 - 4.4e-08 32.3 6.2 0.00057 18.8 0.2 4.8 5 2 2 7 7 7 3 NRDE-2, necessary for RNA interference TPR_2 PF07719.12 EME27500.1 - 4e-07 29.4 18.2 0.0027 17.5 0.2 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME27500.1 - 5.3e-06 26.9 17.9 0.84 10.3 0.7 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME27500.1 - 6.8e-06 25.4 11.6 0.0018 17.9 0.1 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EME27500.1 - 0.0001 21.7 2.8 0.043 13.1 0.0 3.1 3 0 0 3 3 3 2 26S proteasome subunit RPN7 TPR_11 PF13414.1 EME27500.1 - 0.00021 20.8 12.4 0.5 10.0 0.1 6.9 6 0 0 6 6 6 1 TPR repeat TPR_10 PF13374.1 EME27500.1 - 0.0016 18.3 5.3 0.22 11.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME27500.1 - 0.04 13.5 7.5 0.03 13.9 0.8 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EME27500.1 - 0.061 13.6 1.0 40 4.8 0.0 5.1 5 0 0 5 5 5 0 Pentatricopeptide repeat domain PPR PF01535.15 EME27500.1 - 0.062 13.3 5.7 3.9 7.6 0.0 5.3 5 0 0 5 5 4 0 PPR repeat TPR_4 PF07721.9 EME27500.1 - 0.44 11.1 5.4 87 4.0 0.1 4.7 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME27500.1 - 0.88 10.1 6.9 72 4.1 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L19 PF01245.15 EME27501.1 - 2.7e-19 69.0 0.0 3.3e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 zf-RING_2 PF13639.1 EME27502.1 - 4.4e-15 55.2 9.7 4.4e-15 55.2 6.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME27502.1 - 2.1e-09 37.2 10.3 2.1e-09 37.2 7.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27502.1 - 2e-08 33.8 9.0 2e-08 33.8 6.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME27502.1 - 3.3e-08 33.0 8.8 3.3e-08 33.0 6.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME27502.1 - 5.9e-08 32.2 9.8 5.9e-08 32.2 6.8 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME27502.1 - 2.6e-07 30.6 6.7 2.6e-07 30.6 4.6 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 EME27502.1 - 1e-06 28.6 4.9 1e-06 28.6 3.4 3.2 3 0 0 3 3 3 1 zinc-finger zf-RING_UBOX PF13445.1 EME27502.1 - 1.7e-05 24.4 6.8 1.7e-05 24.4 4.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EME27502.1 - 0.0012 18.5 2.9 0.0012 18.5 2.0 2.2 2 1 1 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EME27502.1 - 0.0027 17.1 6.9 0.0027 17.1 4.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Elf1 PF05129.8 EME27502.1 - 0.0036 16.9 1.1 0.0036 16.9 0.8 2.7 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like DZR PF12773.2 EME27502.1 - 0.056 13.2 14.0 1 9.2 0.4 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.1 EME27502.1 - 1 9.2 6.7 0.31 10.8 2.2 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein C1_4 PF07975.7 EME27502.1 - 1 9.4 19.5 2.9 7.9 1.5 3.4 2 1 0 2 2 2 0 TFIIH C1-like domain Mcm10 PF09332.6 EME27502.1 - 1.4 8.1 11.4 0.63 9.3 3.1 2.8 3 0 0 3 3 3 0 Mcm10 replication factor zf-RING_4 PF14570.1 EME27502.1 - 2.2 7.9 15.3 0.07 12.7 5.8 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EME27502.1 - 3.3 7.2 11.9 0.33 10.4 4.8 1.8 2 0 0 2 2 2 0 P-11 zinc finger Thioredoxin PF00085.15 EME27503.1 - 1.6e-05 24.5 0.1 3.6e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EME27503.1 - 0.0042 16.9 0.1 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain KaiB PF07689.7 EME27503.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiB domain HyaE PF07449.6 EME27503.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE GnsAB PF08178.6 EME27503.1 - 3.2 7.4 7.5 15 5.3 1.7 2.9 2 1 1 3 3 3 0 GnsA/GnsB family PseudoU_synth_1 PF01416.15 EME27504.1 - 2.3e-21 76.1 0.0 2.7e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Arm PF00514.18 EME27505.1 - 1.7e-29 100.5 16.0 9.7e-07 28.3 0.3 10.2 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME27505.1 - 1.8e-11 44.1 12.7 0.00038 20.6 0.1 6.6 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.17 EME27505.1 - 0.0001 22.0 7.6 1.1 9.5 0.1 6.6 6 0 0 6 6 6 2 HEAT repeat DUF1546 PF07571.8 EME27505.1 - 0.027 14.5 0.0 0.16 12.0 0.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EME27505.1 - 0.038 14.4 8.0 4 8.0 0.1 5.7 5 1 1 6 6 6 0 HEAT-like repeat Adaptin_N PF01602.15 EME27506.1 - 2.1e-79 267.2 8.3 4e-78 263.0 4.7 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EME27506.1 - 1.7e-09 37.7 0.1 0.00028 21.1 0.0 3.6 1 1 3 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EME27506.1 - 6.2e-08 32.6 6.0 0.00013 21.9 1.2 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EME27506.1 - 0.00018 21.3 1.0 0.31 10.9 0.0 3.7 4 1 0 4 4 4 2 Protein of unknown function (DUF2435) HEAT PF02985.17 EME27506.1 - 0.0005 19.9 6.7 0.25 11.5 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat ParcG PF10274.4 EME27506.1 - 0.0084 16.0 1.5 0.027 14.3 0.2 2.4 2 0 0 2 2 2 1 Parkin co-regulated protein HEAT_EZ PF13513.1 EME27506.1 - 0.026 14.9 4.5 6.6 7.3 0.1 5.2 4 1 2 6 6 6 0 HEAT-like repeat SKI PF01202.17 EME27507.1 - 3.2e-29 101.8 0.0 4.7e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EME27507.1 - 1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME27507.1 - 1.6e-06 28.9 0.0 2.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME27507.1 - 5.5e-06 26.7 0.0 8.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EME27507.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase-like family CoaE PF01121.15 EME27507.1 - 0.00052 19.4 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase DUF258 PF03193.11 EME27507.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EME27507.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EME27507.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 EME27507.1 - 0.032 14.5 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EME27507.1 - 0.051 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EME27507.1 - 0.053 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EME27507.1 - 0.056 12.6 0.2 0.09 12.0 0.0 1.4 2 0 0 2 2 2 0 ADP-ribosylation factor family CPT PF07931.7 EME27507.1 - 0.062 12.9 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 EME27507.1 - 0.087 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME27507.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pectate_lyase_3 PF12708.2 EME27508.1 - 0.0004 20.5 0.8 0.0064 16.6 0.4 2.6 1 1 1 2 2 2 1 Pectate lyase superfamily protein Ala_racemase_C PF00842.16 EME27508.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Indigoidine_A PF04227.7 EME27509.1 - 6.4e-126 419.5 0.1 7.3e-126 419.3 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein RNA_pol_Rpb2_6 PF00562.23 EME27510.1 - 1.2e-127 425.8 0.0 1e-125 419.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME27510.1 - 6.9e-62 207.9 0.0 1.1e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EME27510.1 - 6e-46 156.2 0.0 1.3e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EME27510.1 - 2.6e-31 107.6 0.0 6.5e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EME27510.1 - 8.8e-26 89.5 0.1 2.2e-25 88.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EME27510.1 - 1.3e-24 85.7 0.0 3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EME27510.1 - 2e-16 59.6 2.6 4.4e-16 58.5 1.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Citrate_synt PF00285.16 EME27511.1 - 5.8e-127 423.2 0.0 6.9e-127 423.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Sugar_tr PF00083.19 EME27512.1 - 2.7e-92 309.7 18.9 3.7e-92 309.2 13.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27512.1 - 9.2e-32 110.1 23.8 1.3e-31 109.5 15.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME27512.1 - 6.8e-05 21.2 3.7 6.8e-05 21.2 2.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EME27512.1 - 0.001 18.8 1.7 0.045 13.5 0.2 2.7 2 0 0 2 2 2 1 MFS_1 like family IFP_35_N PF07334.8 EME27512.1 - 0.12 12.4 0.4 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Abi PF02517.11 EME27513.1 - 1.2e-11 44.5 2.6 1.2e-11 44.5 1.8 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity Abi PF02517.11 EME27514.1 - 1.1e-05 25.4 1.3 1.1e-05 25.4 0.9 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity Ribosomal_S27 PF01599.14 EME27515.1 - 5.1e-26 90.2 1.3 9.7e-26 89.3 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EME27515.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Telomere_Sde2 PF13019.1 EME27515.1 - 0.09 12.4 0.2 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Telomere stability and silencing IBR PF01485.16 EME27515.1 - 0.11 12.3 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 IBR domain zf-C2H2_3 PF13878.1 EME27515.1 - 0.13 11.8 0.2 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Thioredoxin PF00085.15 EME27516.1 - 6e-23 80.4 0.1 6.7e-23 80.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME27516.1 - 1.7e-06 28.1 0.2 1.6e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME27516.1 - 2.9e-06 27.3 0.3 0.00041 20.4 0.2 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EME27516.1 - 3.2e-05 23.8 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EME27516.1 - 0.00037 20.0 0.1 0.00039 19.9 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 EME27516.1 - 0.00047 19.7 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME27516.1 - 0.00077 19.1 0.1 0.00092 18.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF953 PF06110.6 EME27516.1 - 0.014 14.7 0.0 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Pex14_N PF04695.8 EME27517.1 - 2.2e-24 86.0 2.0 2.2e-24 86.0 1.4 3.5 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1515 PF07439.6 EME27517.1 - 1.7 8.4 5.9 0.21 11.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Radical_SAM PF04055.16 EME27518.1 - 9.9e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.11 EME27518.1 - 2.6e-07 30.6 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 HemN C-terminal domain DUF3834 PF12916.2 EME27518.1 - 0.0036 16.3 0.0 0.039 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3834) RPA_C PF08784.6 EME27518.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal XRN_N PF03159.13 EME27519.1 - 2e-89 299.0 0.0 3.7e-89 298.1 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus eIF3_p135 PF12807.2 EME27519.1 - 0.07 13.0 1.8 0.19 11.6 1.2 1.7 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Clathrin_lg_ch PF01086.12 EME27520.1 - 5.8e-10 39.4 7.6 5.8e-10 39.4 5.3 1.6 2 0 0 2 2 2 1 Clathrin light chain Mt_ATP-synt_B PF05405.9 EME27520.1 - 0.029 13.8 1.8 0.03 13.7 0.5 1.5 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Caudo_TAP PF02413.12 EME27520.1 - 0.17 12.0 2.8 0.088 12.9 0.6 1.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Ribosomal_L30_N PF08079.7 EME27520.1 - 1.9 8.5 13.9 0.43 10.6 6.7 2.0 2 1 0 2 2 2 0 Ribosomal L30 N-terminal domain Ribosomal_L44 PF00935.14 EME27521.1 - 1.5e-34 117.7 12.0 1.9e-34 117.4 8.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 EME27521.1 - 0.0037 17.0 1.0 0.0037 17.0 0.7 2.2 1 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.15 EME27521.1 - 0.062 13.5 1.4 0.062 13.5 1.0 2.5 2 1 0 2 2 2 0 Ribosomal protein L33 Ribosomal_L2_C PF03947.13 EME27522.1 - 1.5e-51 173.5 0.8 2.1e-51 173.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EME27522.1 - 3.4e-21 74.9 0.1 8.3e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SecE PF00584.15 EME27523.1 - 1.1e-11 44.0 0.2 1.6e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF1911 PF08929.5 EME27523.1 - 0.057 14.1 0.0 0.093 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) DnaJ PF00226.26 EME27524.1 - 1.5e-24 85.4 1.6 4.2e-24 84.0 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 EME27524.1 - 3.1e-12 46.6 0.1 3.1e-12 46.6 0.1 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1977) GnsAB PF08178.6 EME27524.1 - 0.17 11.5 1.5 0.36 10.5 1.0 1.5 1 0 0 1 1 1 0 GnsA/GnsB family TPR_2 PF07719.12 EME27524.1 - 8.6 6.5 6.0 32 4.7 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.16 EME27525.1 - 0.0025 18.1 0.1 0.0025 18.1 0.1 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase KxDL PF10241.4 EME27526.1 - 0.063 13.1 1.7 0.082 12.8 0.4 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Adeno_E3B PF03376.9 EME27526.1 - 0.09 12.6 1.3 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Adenovirus E3B protein Complex1_LYR PF05347.10 EME27526.1 - 0.17 11.6 1.7 0.47 10.2 0.1 2.4 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Sugar_tr PF00083.19 EME27527.1 - 4.5e-83 279.3 21.6 5.8e-83 278.9 15.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27527.1 - 2e-27 95.8 26.9 2e-27 95.8 18.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME27527.1 - 8.7e-07 27.5 10.1 1.7e-06 26.5 3.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PseudoU_synth_2 PF00849.17 EME27528.1 - 2.3e-19 69.7 0.0 6.1e-19 68.4 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EME27528.1 - 4.3e-11 42.0 0.2 3.1e-10 39.3 0.0 2.5 2 1 1 3 3 3 1 S4 domain NAC PF01849.13 EME27529.1 - 1.2e-24 85.5 0.1 3.3e-23 80.9 0.1 2.4 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EME27529.1 - 0.00036 20.2 0.8 0.00083 19.1 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain SelP_N PF04592.9 EME27529.1 - 2 7.7 11.1 3.6 6.9 7.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PTRF_SDPR PF15237.1 EME27529.1 - 3.9 6.8 13.0 1 8.6 4.6 2.0 2 0 0 2 2 2 0 PTRF/SDPR family Zip PF02535.17 EME27529.1 - 7.6 5.4 10.1 12 4.8 7.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Alba PF01918.16 EME27530.1 - 4e-14 51.9 0.2 6.2e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 EME27530.1 - 0.0056 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P CAMP_factor PF07373.6 EME27530.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 CAMP factor (Cfa) Glyco_hydro_53 PF07745.8 EME27530.1 - 0.21 10.3 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 FliD_N PF02465.13 EME27531.1 - 1.1 9.6 6.4 1.1 9.6 0.2 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WD40 PF00400.27 EME27534.1 - 8.1e-32 107.9 13.0 1.6e-10 40.4 0.3 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.6 EME27534.1 - 6.5e-23 81.0 1.7 2.4e-21 75.9 0.2 3.9 3 1 0 3 3 3 1 TUP1-like enhancer of split eIF2A PF08662.6 EME27534.1 - 0.00065 19.4 0.0 6.3 6.4 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EME27535.1 - 8.1e-32 107.9 13.0 1.6e-10 40.4 0.3 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.6 EME27535.1 - 6.5e-23 81.0 1.7 2.4e-21 75.9 0.2 3.9 3 1 0 3 3 3 1 TUP1-like enhancer of split eIF2A PF08662.6 EME27535.1 - 0.00065 19.4 0.0 6.3 6.4 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Alpha_adaptin_C PF02296.11 EME27536.1 - 0.02 14.8 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain DUF444 PF04285.7 EME27537.1 - 0.037 12.6 0.7 0.042 12.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF3574 PF12098.3 EME27537.1 - 0.077 12.5 0.4 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Arch_ATPase PF01637.13 EME27538.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CN_hydrolase PF00795.17 EME27539.1 - 1.7e-25 89.4 0.0 3.6e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_11 PF08241.7 EME27540.1 - 3.2e-20 72.4 0.0 5.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME27540.1 - 3.1e-13 49.9 0.0 7.8e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME27540.1 - 3.1e-13 49.3 0.0 6.5e-12 45.0 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EME27540.1 - 1.7e-12 47.1 0.0 2.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME27540.1 - 3.9e-12 46.1 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME27540.1 - 4.3e-11 43.1 0.0 1.6e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME27540.1 - 8e-07 29.0 0.0 2.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME27540.1 - 8e-06 26.4 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EME27540.1 - 0.00011 21.3 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EME27540.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DUF3010 PF11215.3 EME27540.1 - 0.00036 20.4 0.0 0.00076 19.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3010) PCMT PF01135.14 EME27540.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GST_N_3 PF13417.1 EME27541.1 - 2.4e-18 66.0 0.3 6.5e-17 61.5 0.0 3.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME27541.1 - 4e-10 39.5 0.1 1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME27541.1 - 3.1e-06 26.9 0.6 6.9e-06 25.8 0.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME27541.1 - 0.00016 21.6 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME27541.1 - 0.0004 20.8 0.1 0.00095 19.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EME27541.1 - 0.02 14.8 0.1 0.048 13.6 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin Peptidase_C48 PF02902.14 EME27542.1 - 7.9e-21 74.6 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Trypsin_2 PF13365.1 EME27543.1 - 9.9e-17 61.0 0.2 1.7e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EME27543.1 - 8.2e-16 58.2 0.1 1.3e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EME27543.1 - 1.8e-09 37.3 0.0 1.5e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Peptidase_S7 PF00949.16 EME27543.1 - 0.0068 15.8 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EME27543.1 - 0.043 12.2 0.1 0.084 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 PDZ PF00595.19 EME27543.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 EME27544.1 - 9.5e-17 61.0 0.2 1.6e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EME27544.1 - 7.8e-16 58.3 0.1 1.3e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EME27544.1 - 6.5e-11 41.9 0.0 5.4e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Peptidase_S7 PF00949.16 EME27544.1 - 0.0064 15.8 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.19 EME27544.1 - 0.0067 16.5 0.0 0.022 14.9 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 EME27544.1 - 0.041 12.2 0.1 0.081 11.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 DUF547 PF04784.9 EME27545.1 - 7.6e-11 41.9 0.0 3.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF547 DEP PF00610.16 EME27545.1 - 5.2e-08 32.5 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2398 PF09661.5 EME27545.1 - 0.13 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) SelR PF01641.13 EME27546.1 - 4.3e-50 168.5 0.1 5.8e-50 168.1 0.1 1.2 1 0 0 1 1 1 1 SelR domain Endonuclease_7 PF02945.10 EME27546.1 - 0.02 14.5 0.4 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 Recombination endonuclease VII Yippee-Mis18 PF03226.9 EME27546.1 - 0.021 14.8 0.5 0.082 12.9 0.1 2.1 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EME27546.1 - 0.082 12.8 1.3 6 6.8 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-HIT PF04438.11 EME27546.1 - 0.78 9.4 7.6 0.74 9.5 0.4 2.8 3 0 0 3 3 3 0 HIT zinc finger zf-Mss51 PF13824.1 EME27546.1 - 0.88 9.4 3.2 0.38 10.6 0.3 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Tnp_zf-ribbon_2 PF13842.1 EME27546.1 - 5.6 7.4 6.2 6.2 7.3 0.3 2.7 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DNA_binding_1 PF01035.15 EME27547.1 - 6.6e-26 89.8 0.0 9e-26 89.4 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF1284 PF06935.6 EME27547.1 - 0.025 14.7 0.5 0.064 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Clat_adaptor_s PF01217.15 EME27548.1 - 6.1e-51 171.8 3.1 7.9e-51 171.5 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UDG PF03167.14 EME27549.1 - 4.8e-27 94.2 0.0 7.5e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily V-ATPase_H_N PF03224.9 EME27550.1 - 8.7e-36 123.6 9.2 8.7e-36 123.6 6.4 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EME27550.1 - 2.8e-29 101.4 2.4 1.5e-28 99.0 0.2 2.7 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 EME27550.1 - 0.085 13.1 0.3 7.1 6.9 0.2 3.4 3 0 0 3 3 3 0 HEAT repeats V-ATPase_H_N PF03224.9 EME27551.1 - 5.7e-36 124.2 9.2 5.7e-36 124.2 6.4 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EME27551.1 - 3.2e-24 85.1 1.2 4.4e-23 81.4 0.1 2.8 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 EME27551.1 - 0.062 13.5 0.5 5.8 7.2 0.2 3.4 3 0 0 3 3 3 0 HEAT repeats Epimerase PF01370.16 EME27552.1 - 1.4e-58 198.1 0.0 1.6e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME27552.1 - 8.5e-22 77.1 0.0 1.2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME27552.1 - 3.7e-20 71.9 0.0 5.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EME27552.1 - 1.1e-18 67.0 0.0 4.7e-18 65.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EME27552.1 - 8.2e-18 64.3 0.0 3.7e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EME27552.1 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME27552.1 - 0.00046 20.1 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EME27552.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 EME27552.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 EME27552.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 KR domain Galactosyl_T PF01762.16 EME27553.1 - 1.6e-33 115.9 0.0 2.9e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 EME27553.1 - 0.02 14.1 0.0 0.039 13.1 0.0 1.5 1 1 0 1 1 1 0 Fringe-like LST1 PF05083.8 EME27553.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein Band_7 PF01145.20 EME27554.1 - 5.9e-31 107.7 0.1 1.1e-30 106.8 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EME27554.1 - 0.0089 15.5 0.1 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 SPFH domain-Band 7 family Herpes_UL42 PF02282.11 EME27554.1 - 0.073 12.6 0.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) zf-RING_2 PF13639.1 EME27555.1 - 6.2e-13 48.3 4.5 9.7e-13 47.7 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME27555.1 - 4.3e-08 33.0 5.7 7.5e-08 32.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME27555.1 - 4.5e-08 32.6 2.7 8e-08 31.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27555.1 - 4.5e-07 29.4 3.2 7.5e-07 28.7 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME27555.1 - 1e-06 28.7 4.3 3.2e-06 27.1 3.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME27555.1 - 1.1e-05 25.1 1.0 1.8e-05 24.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EME27555.1 - 1.2e-05 24.9 2.0 2.1e-05 24.1 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME27555.1 - 0.00032 20.3 0.9 0.00058 19.5 0.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EME27555.1 - 0.0044 16.5 1.1 0.0076 15.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EME27555.1 - 0.005 16.8 4.1 0.01 15.8 2.9 1.5 1 0 0 1 1 1 1 RING-variant domain Vps39_2 PF10367.4 EME27555.1 - 0.013 15.6 2.9 0.26 11.4 0.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_1 PF00130.17 EME27555.1 - 0.017 14.7 4.5 0.04 13.6 0.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_4 PF15227.1 EME27555.1 - 0.036 13.9 6.9 1.3 8.9 5.0 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.7 EME27555.1 - 0.045 13.8 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EME27555.1 - 0.32 10.7 2.4 3.7 7.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-MIZ PF02891.15 EME27555.1 - 0.48 9.9 4.1 1.1 8.8 2.9 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger FYVE PF01363.16 EME27555.1 - 1.2 9.1 4.8 7.4 6.5 0.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger FANCL_C PF11793.3 EME27555.1 - 2 8.4 5.5 15 5.6 3.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain UPF0547 PF10571.4 EME27555.1 - 4.1 7.1 6.9 2.4 7.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-RING_6 PF14835.1 EME27555.1 - 4.3 7.2 8.7 1.1 9.0 3.3 2.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein TPR_16 PF13432.1 EME27556.1 - 3.5e-05 24.3 4.8 0.12 13.0 0.1 3.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME27556.1 - 0.0002 21.0 2.4 0.021 14.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME27556.1 - 0.00038 20.0 4.8 0.056 13.1 0.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 EME27556.1 - 0.0066 16.7 0.6 2.3 8.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME27556.1 - 0.017 15.6 0.2 18 6.3 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME27556.1 - 0.14 11.7 2.7 1.3 8.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME27558.1 - 0.058 14.0 3.9 0.064 13.9 0.1 2.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME27558.1 - 0.14 11.8 1.6 0.74 9.5 0.2 2.2 1 1 1 2 2 2 0 TPR repeat TPR_2 PF07719.12 EME27558.1 - 0.14 12.1 1.9 13 5.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EME27559.1 - 4.5e-37 128.1 0.0 5.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME27559.1 - 1.7e-14 53.8 0.0 8.9e-14 51.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME27559.1 - 6.1e-13 48.8 0.0 1.3e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME27559.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EME27559.1 - 0.00047 19.5 0.0 0.0026 17.0 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EME27559.1 - 0.004 16.8 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.9 EME27559.1 - 0.043 12.2 0.0 0.073 11.5 0.0 1.4 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.5 EME27559.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Peptidase_S9 PF00326.16 EME27559.1 - 0.075 12.2 0.0 0.75 8.9 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Mito_carr PF00153.22 EME27560.1 - 1e-57 191.8 0.4 1.6e-22 78.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein L_biotic_typeA PF04604.8 EME27560.1 - 0.012 15.2 0.0 0.098 12.3 0.0 2.5 3 0 0 3 3 3 0 Type-A lantibiotic Glutaredoxin PF00462.19 EME27561.1 - 2.7e-19 68.9 0.0 5.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EME27561.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UCH PF00443.24 EME27563.1 - 2.8e-50 170.9 2.3 3.3e-50 170.6 1.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME27563.1 - 1e-22 80.9 3.6 1.4e-22 80.5 2.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-amylase PF00128.19 EME27564.1 - 3.3e-23 82.5 0.2 1.8e-22 80.1 0.0 2.2 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Pkinase PF00069.20 EME27565.1 - 9.2e-79 264.2 0.0 1e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27565.1 - 5.9e-34 117.3 0.0 7.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME27565.1 - 0.00012 21.1 0.1 0.0041 16.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EME27565.1 - 0.0058 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EME27565.1 - 0.012 15.3 0.1 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EME27566.1 - 2.1e-78 263.0 0.0 2.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27566.1 - 6.8e-34 117.1 0.0 8.6e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME27566.1 - 0.00015 20.8 0.1 0.0058 15.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EME27566.1 - 0.0062 15.4 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EME27566.1 - 0.013 15.2 0.1 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.22 EME27567.1 - 1e-40 139.6 0.0 3.7e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EME27567.1 - 5.8e-13 48.0 3.7 6e-13 47.9 1.2 2.2 2 0 0 2 2 2 1 FATC domain UME PF08064.8 EME27567.1 - 9.7e-07 28.7 4.4 2.6e-06 27.3 0.3 3.5 2 0 0 2 2 2 1 UME (NUC010) domain TPR_12 PF13424.1 EME27567.1 - 0.058 13.3 1.9 0.33 10.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Branch PF02485.16 EME27568.1 - 6.2e-24 84.4 2.0 9.5e-24 83.8 1.4 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme AIG2 PF06094.7 EME27568.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family SAPS PF04499.10 EME27569.1 - 9.5e-14 50.8 0.9 9.5e-14 50.8 0.6 4.0 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein tRNA-synt_1 PF00133.17 EME27570.1 - 2.8e-181 603.6 0.0 3.5e-181 603.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME27570.1 - 4.3e-28 97.9 0.1 1.5e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME27570.1 - 6.1e-23 81.1 0.1 4.6e-12 45.2 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EME27570.1 - 5.4e-08 32.2 4.0 1.3e-07 31.0 2.8 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EME27570.1 - 0.00052 19.3 0.0 0.00096 18.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 ThiF PF00899.16 EME27571.1 - 3.6e-43 146.6 0.2 5.6e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EME27571.1 - 2e-28 97.8 0.3 5.4e-28 96.4 0.2 1.8 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EME27571.1 - 1.5e-06 28.5 0.0 7.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 EME27571.1 - 0.00022 21.3 0.6 0.0045 17.0 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EME27571.1 - 0.059 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EME27571.1 - 0.13 11.6 0.1 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EME27571.1 - 0.13 11.0 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 EME27571.1 - 0.2 10.5 2.3 0.34 9.7 1.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EME27571.1 - 0.62 9.4 2.8 1.5 8.2 1.9 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EME27571.1 - 1.3 8.0 4.3 3.1 6.7 2.5 1.8 1 1 1 2 2 2 0 FAD binding domain Cupin_4 PF08007.7 EME27572.1 - 2.5e-60 204.4 0.0 3.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 EME27572.1 - 0.0002 20.9 0.3 0.0055 16.2 0.2 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EME27572.1 - 0.048 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain HlyIII PF03006.15 EME27573.1 - 2e-44 151.6 23.8 2.3e-44 151.4 16.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related EamA PF00892.15 EME27573.1 - 0.045 13.7 0.4 0.045 13.7 0.3 3.1 2 1 1 3 3 3 0 EamA-like transporter family ACPS PF01648.15 EME27574.1 - 3.2e-16 59.1 0.0 3.1e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily zf-HIT PF04438.11 EME27574.1 - 0.00067 19.2 13.5 0.00067 19.2 9.3 2.4 2 1 0 2 2 2 1 HIT zinc finger SPX PF03105.14 EME27575.1 - 0.00019 21.3 5.4 0.00023 21.0 3.7 1.1 1 0 0 1 1 1 1 SPX domain HJURP_mid PF12346.3 EME27575.1 - 2.1 8.5 5.6 0.49 10.5 1.1 2.0 2 1 1 3 3 3 0 Holliday junction recognition protein-associated repeat Sld5 PF05916.6 EME27576.1 - 3.9e-19 68.9 0.6 6.7e-19 68.1 0.4 1.4 1 0 0 1 1 1 1 GINS complex protein SLX9 PF15341.1 EME27577.1 - 2.5e-12 47.2 7.3 2.5e-12 47.2 5.0 2.0 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 GrpE PF01025.14 EME27577.1 - 0.13 11.8 6.5 0.2 11.1 4.3 1.6 1 1 0 1 1 1 0 GrpE Peptidase_C65 PF10275.4 EME27577.1 - 0.3 10.3 3.0 0.34 10.2 1.7 1.4 1 1 0 1 1 1 0 Peptidase C65 Otubain V_ATPase_I PF01496.14 EME27577.1 - 1 7.1 9.3 1.1 7.0 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_6 PF01441.14 EME27577.1 - 1.3 8.8 5.3 0.56 10.0 2.2 1.5 2 0 0 2 2 2 0 Lipoprotein REV PF00424.13 EME27577.1 - 4.4 7.2 10.4 0.92 9.4 3.2 2.3 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) CYTH PF01928.16 EME27578.1 - 2e-11 43.9 1.9 2.8e-11 43.4 1.3 1.2 1 0 0 1 1 1 1 CYTH domain SATase_N PF06426.9 EME27579.1 - 6.3e-38 129.2 0.4 1.3e-37 128.2 0.3 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.19 EME27579.1 - 5.3e-11 41.5 9.5 8.2e-08 31.4 0.5 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME27579.1 - 0.81 9.3 8.4 0.49 9.9 0.7 2.9 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase MSC PF09402.5 EME27580.1 - 0.31 9.6 5.9 0.36 9.4 4.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain UvrD-helicase PF00580.16 EME27581.1 - 2e-47 162.0 2.7 1.8e-45 155.6 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EME27581.1 - 2.4e-34 119.3 9.5 2.4e-34 119.3 6.6 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EME27581.1 - 6.9e-10 38.5 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EME27581.1 - 2.4e-08 34.0 0.1 6.9e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EME27581.1 - 2.7e-07 30.3 2.8 0.0081 15.7 1.2 3.8 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EME27581.1 - 0.00039 19.8 2.8 0.035 13.4 0.1 3.2 4 1 1 5 5 5 2 AAA domain DEAD PF00270.24 EME27581.1 - 0.015 14.7 0.0 0.074 12.5 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 EME27581.1 - 0.047 13.2 0.0 2.8 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain ThiF PF00899.16 EME27582.1 - 6.6e-39 132.8 0.4 7.6e-38 129.4 0.1 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EME27582.1 - 1.6e-22 78.8 0.1 3.4e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EME27582.1 - 2.1e-20 72.2 0.0 4.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EME27582.1 - 1.9e-14 52.7 1.4 4.1e-14 51.6 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EME27582.1 - 0.00039 19.9 0.0 0.00082 18.9 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EME27582.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IDO PF01231.13 EME27582.1 - 0.043 12.2 0.0 0.059 11.7 0.0 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase UAE_UbL PF14732.1 EME27582.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain MFS_1 PF07690.11 EME27583.1 - 7.3e-33 113.7 27.8 4.7e-25 88.0 4.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME27583.1 - 5.2e-10 38.4 3.5 5.2e-10 38.4 2.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Snf7 PF03357.16 EME27584.1 - 1.2e-20 73.5 9.7 1.4e-20 73.3 6.8 1.0 1 0 0 1 1 1 1 Snf7 Lipoprotein_2 PF00921.12 EME27584.1 - 0.011 15.7 2.4 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 Borrelia lipoprotein FATC PF02260.15 EME27584.1 - 0.15 11.5 0.4 0.38 10.2 0.3 1.7 1 0 0 1 1 1 0 FATC domain YlqD PF11068.3 EME27584.1 - 3 7.8 10.1 3.9 7.5 4.7 2.1 2 0 0 2 2 2 0 YlqD protein DUF2363 PF10155.4 EME27585.1 - 2e-52 176.4 8.0 3.4e-52 175.6 5.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Iso_dh PF00180.15 EME27586.1 - 4.2e-71 239.7 0.0 5.1e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Apyrase PF06079.6 EME27587.1 - 3.5e-91 305.3 0.1 4.9e-91 304.9 0.1 1.2 1 0 0 1 1 1 1 Apyrase zf-RING_2 PF13639.1 EME27588.1 - 2.4e-14 52.8 6.6 4.8e-14 51.9 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME27588.1 - 3.2e-08 33.0 5.3 6.5e-08 32.0 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27588.1 - 1.6e-07 30.9 1.5 3.3e-07 29.8 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME27588.1 - 3.1e-07 30.3 8.1 9.4e-07 28.8 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME27588.1 - 7e-07 29.1 6.5 1.5e-06 28.1 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27588.1 - 9.2e-07 28.5 3.3 1.9e-06 27.5 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME27588.1 - 2.8e-05 23.8 1.5 5.8e-05 22.8 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EME27588.1 - 0.00011 21.9 0.3 0.00019 21.2 0.2 1.4 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EME27588.1 - 0.013 15.1 2.3 0.06 13.0 0.3 2.6 1 1 1 2 2 2 0 RING-type zinc-finger Stimulus_sens_1 PF13756.1 EME27588.1 - 0.08 13.3 0.2 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 Stimulus-sensing domain zf-RING_6 PF14835.1 EME27588.1 - 0.15 11.9 1.1 0.29 10.9 0.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.6 EME27588.1 - 0.19 11.7 3.4 0.37 10.8 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EME27588.1 - 0.19 11.2 1.7 0.44 10.1 1.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EME27588.1 - 0.25 11.4 6.2 0.82 9.7 4.4 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME27588.1 - 1.7 8.7 6.9 10 6.1 4.8 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain Ubiq_cyt_C_chap PF03981.7 EME27589.1 - 2.4e-12 46.8 1.5 2e-11 43.8 1.0 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone GATase_5 PF13507.1 EME27590.1 - 1.4e-97 325.6 0.0 2.2e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EME27590.1 - 4.1e-40 137.2 0.1 5.1e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME27590.1 - 9.4e-15 54.6 0.4 2.7e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain GATase_5 PF13507.1 EME27591.1 - 1.4e-97 325.6 0.0 2.2e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EME27591.1 - 4.1e-40 137.2 0.1 5.1e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME27591.1 - 4.8e-17 61.9 0.3 1.5e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain Methyltransf_31 PF13847.1 EME27592.1 - 1e-09 38.1 0.0 1.1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME27592.1 - 1.4e-07 31.8 0.0 1.7e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME27592.1 - 2e-07 31.4 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME27592.1 - 5.7e-07 30.1 0.0 6.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME27592.1 - 7.6e-07 29.4 0.0 8.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME27592.1 - 5.6e-05 22.3 0.0 6.1e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EME27592.1 - 6.3e-05 22.4 0.0 7.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME27592.1 - 6.7e-05 22.9 0.0 7.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME27592.1 - 0.0004 20.1 0.0 0.0004 20.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME27592.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.6 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EME27592.1 - 0.0039 16.2 0.0 0.0039 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EME27592.1 - 0.0042 16.2 0.0 0.0042 16.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 EME27592.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme MetW PF07021.7 EME27592.1 - 0.022 14.1 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.8 EME27592.1 - 0.025 13.8 0.0 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_2 PF00891.13 EME27592.1 - 0.039 13.1 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Glycos_transf_2 PF00535.21 EME27593.1 - 8.7e-30 103.6 0.0 1.7e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EME27593.1 - 4.6e-20 71.8 0.0 1.9e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EME27593.1 - 2.9e-15 56.6 0.0 2.7e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EME27593.1 - 0.02 14.3 0.5 0.052 13.0 0.4 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_tranf_2_4 PF13704.1 EME27593.1 - 0.098 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Suf PF05843.9 EME27594.1 - 1.5e-41 143.0 0.2 1.5e-41 143.0 0.1 3.4 2 2 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EME27594.1 - 6e-08 32.6 0.5 0.085 13.5 0.0 6.2 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME27594.1 - 0.00052 20.6 9.4 0.039 14.6 0.1 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME27594.1 - 0.00064 19.3 8.9 0.002 17.7 0.2 3.6 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 EME27594.1 - 0.015 14.9 3.7 6.4 6.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME27594.1 - 0.025 14.4 3.2 7 6.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME27594.1 - 0.11 12.9 1.0 11 6.4 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME27594.1 - 1.8 8.5 6.9 1.4 8.8 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF972 PF06156.8 EME27595.1 - 2.8e-05 24.4 2.6 2.8e-05 24.4 1.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF972) HALZ PF02183.13 EME27595.1 - 0.00075 19.1 0.1 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.12 EME27595.1 - 0.0015 18.7 13.7 0.0015 18.7 9.5 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EME27595.1 - 0.0058 16.5 17.5 0.23 11.4 12.2 2.5 1 1 0 1 1 1 1 bZIP transcription factor MAD PF05557.8 EME27595.1 - 0.0081 14.3 6.6 0.011 13.8 4.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein bZIP_2 PF07716.10 EME27595.1 - 0.013 15.2 2.2 0.013 15.2 1.6 3.2 3 1 1 4 4 3 0 Basic region leucine zipper DivIC PF04977.10 EME27595.1 - 0.025 14.0 2.8 0.025 14.0 1.9 2.5 3 0 0 3 3 3 0 Septum formation initiator DUF904 PF06005.7 EME27595.1 - 0.13 12.5 10.4 0.55 10.5 7.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2205 PF10224.4 EME27595.1 - 0.17 11.4 4.2 0.38 10.3 2.9 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) CAF-1_p150 PF11600.3 EME27595.1 - 0.66 9.3 13.5 0.19 11.0 7.3 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EME27595.1 - 0.88 8.5 4.9 1.3 8.0 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EME27595.1 - 3.6 6.4 10.5 5.5 5.8 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tbf5 PF06331.7 EME27596.1 - 6.9e-23 80.2 0.0 7.4e-23 80.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 TPM PF04536.9 EME27597.1 - 6.6e-09 35.6 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase COPI_assoc PF08507.5 EME27598.1 - 5.4e-26 90.9 8.3 6.4e-26 90.6 5.7 1.0 1 0 0 1 1 1 1 COPI associated protein ARL6IP6 PF15062.1 EME27598.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix IncA PF04156.9 EME27598.1 - 0.28 10.7 7.7 26 4.3 6.8 2.1 2 0 0 2 2 2 0 IncA protein COPI_assoc PF08507.5 EME27599.1 - 5.4e-26 90.9 8.3 6.4e-26 90.6 5.7 1.0 1 0 0 1 1 1 1 COPI associated protein ARL6IP6 PF15062.1 EME27599.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix IncA PF04156.9 EME27599.1 - 0.28 10.7 7.7 26 4.3 6.8 2.1 2 0 0 2 2 2 0 IncA protein PK PF00224.16 EME27600.1 - 5.1e-152 505.4 7.0 6.7e-152 505.0 4.5 1.4 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EME27600.1 - 6.5e-29 99.8 2.9 1.6e-28 98.6 1.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EME27600.1 - 0.00022 20.1 0.6 0.00049 19.0 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EME27600.1 - 0.0058 15.5 0.1 0.027 13.3 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain WD40 PF00400.27 EME27602.1 - 5.3e-15 54.6 8.3 0.00058 19.6 1.7 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat RE_HindVP PF09519.5 EME27602.1 - 0.088 11.6 0.4 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 HindVP restriction endonuclease WHIM1 PF15612.1 EME27604.1 - 5.5e-05 22.8 0.1 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Cnd1 PF12717.2 EME27605.1 - 2.5e-59 200.1 14.4 2e-55 187.4 1.5 4.4 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EME27605.1 - 1.3e-14 54.1 2.7 1.3e-14 54.1 1.9 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_EZ PF13513.1 EME27605.1 - 4.5e-06 26.9 0.1 4 8.0 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EME27605.1 - 9.4e-06 25.8 0.1 2.4 8.5 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EME27605.1 - 0.00047 20.0 0.5 2 8.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Cohesin_HEAT PF12765.2 EME27605.1 - 0.072 13.0 3.7 0.96 9.4 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF1903 PF08991.5 EME27606.1 - 9.3e-06 25.7 0.3 1.2e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EME27606.1 - 0.0044 16.9 0.8 0.0077 16.1 0.6 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EME27606.1 - 0.007 16.3 0.3 0.019 14.9 0.0 1.8 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pil1 PF13805.1 EME27606.1 - 0.041 13.0 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 Myb_DNA-bind_6 PF13921.1 EME27607.1 - 1.7e-46 156.1 15.0 4.5e-11 42.6 0.0 6.0 4 2 2 6 6 6 6 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME27607.1 - 1.5e-41 140.2 6.6 1.2e-12 47.6 0.1 6.1 6 0 0 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.5 EME27607.1 - 5.1e-05 22.9 3.8 2.6 7.7 0.3 5.2 2 2 2 5 5 5 2 SLIDE Myb_DNA-bind_2 PF08914.6 EME27607.1 - 8.7e-05 22.2 0.5 20 5.0 0.0 5.8 5 1 1 6 6 6 1 Rap1 Myb domain Rap1_C PF11626.3 EME27607.1 - 0.012 15.5 0.8 34 4.3 0.5 4.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WIYLD PF10440.4 EME27607.1 - 0.43 10.5 3.3 6.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain Myb_DNA-bind_6 PF13921.1 EME27608.1 - 1.6e-46 156.2 16.0 4.6e-11 42.6 0.0 6.0 4 2 2 6 6 6 6 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME27608.1 - 3.4e-41 139.0 7.5 1.3e-12 47.5 0.1 6.1 6 0 0 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.5 EME27608.1 - 4.9e-05 23.0 3.9 2.6 7.8 0.3 5.3 2 2 2 5 5 5 2 SLIDE Myb_DNA-bind_2 PF08914.6 EME27608.1 - 0.00012 21.7 0.7 21 5.0 0.0 5.8 5 1 1 6 6 6 1 Rap1 Myb domain Rap1_C PF11626.3 EME27608.1 - 0.0043 16.9 0.4 32 4.5 0.4 4.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WIYLD PF10440.4 EME27608.1 - 0.44 10.5 3.3 6.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain Helicase_C_2 PF13307.1 EME27609.1 - 6.2e-45 153.1 0.1 1.5e-43 148.6 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME27609.1 - 1.5e-44 151.4 0.8 3.7e-44 150.1 0.5 1.7 2 0 0 2 2 2 1 DEAD_2 DUF1227 PF06777.6 EME27609.1 - 6.7e-38 129.6 0.2 2.9e-37 127.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) ResIII PF04851.10 EME27609.1 - 5.9e-05 22.9 0.2 0.0073 16.1 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EME27609.1 - 0.00067 19.1 0.3 0.39 10.2 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EME27609.1 - 0.014 14.1 0.1 0.16 10.7 0.1 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.1 EME27609.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Slx4 PF09494.5 EME27609.1 - 0.019 14.6 0.0 2.1 8.1 0.0 3.3 3 0 0 3 3 3 0 Slx4 endonuclease Hexapep PF00132.19 EME27610.1 - 2.8e-26 89.8 30.5 1.3e-07 30.8 2.2 5.6 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME27610.1 - 1e-07 31.3 34.1 0.0002 20.8 4.1 5.6 3 3 3 6 6 6 5 Hexapeptide repeat of succinyl-transferase CART PF06373.6 EME27610.1 - 0.17 11.8 3.4 0.61 10.0 0.5 2.5 1 1 1 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Cyt-b5 PF00173.23 EME27611.1 - 4.3e-25 87.3 0.1 5.8e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3931 PF13082.1 EME27611.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) NUDIX PF00293.23 EME27612.1 - 1.2e-25 89.7 0.0 2e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TUG-UBL1 PF11470.3 EME27614.1 - 2.2e-14 53.1 2.7 1.9e-13 50.0 0.5 2.5 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EME27614.1 - 0.0011 18.9 0.1 0.018 15.0 0.0 2.8 2 0 0 2 2 2 1 UBX domain dCMP_cyt_deam_1 PF00383.17 EME27615.1 - 5.5e-20 70.9 0.2 7.9e-20 70.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME27615.1 - 0.016 14.8 0.2 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF2162 PF09930.4 EME27615.1 - 0.15 11.1 1.0 0.2 10.7 0.7 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) zf-C3H1 PF10650.4 EME27616.1 - 9e-08 31.4 2.0 1.6e-07 30.6 1.4 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_14 PF13428.1 EME27616.1 - 0.34 11.6 2.1 0.38 11.5 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2840 PF11000.3 EME27622.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) DUF782 PF05614.6 EME27622.1 - 0.14 12.3 0.2 0.43 10.7 0.1 1.8 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) GTP_EFTU PF00009.22 EME27629.1 - 6.1e-60 201.8 0.0 8.3e-60 201.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME27629.1 - 3.1e-30 104.2 0.4 9e-30 102.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME27629.1 - 6.8e-18 64.5 5.0 1.9e-17 63.1 3.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EME27629.1 - 2.4e-06 27.0 1.0 5.9e-06 25.8 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EME27629.1 - 7.2e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME27629.1 - 0.0034 17.8 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 EME27629.1 - 0.042 13.3 0.2 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EME27629.1 - 0.11 11.9 0.1 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain adh_short_C2 PF13561.1 EME27630.1 - 8.2e-80 268.0 0.0 1e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME27630.1 - 9.8e-11 41.8 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.3 EME27630.1 - 0.0016 17.4 0.1 0.1 11.5 0.0 2.9 2 1 1 3 3 3 1 Trans-2-enoyl-CoA reductase catalytic region KR PF08659.5 EME27630.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EME27630.1 - 0.048 12.5 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EME27631.1 - 8.4e-80 268.0 0.0 1.1e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME27631.1 - 1e-10 41.8 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.3 EME27631.1 - 0.0017 17.4 0.1 0.11 11.5 0.0 2.9 2 1 1 3 3 3 1 Trans-2-enoyl-CoA reductase catalytic region KR PF08659.5 EME27631.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EME27631.1 - 0.049 12.5 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BCIP PF13862.1 EME27632.1 - 2.9e-08 33.4 0.1 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein LpxB PF02684.10 EME27633.1 - 1.5e-69 234.4 0.0 1.8e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 EME27633.1 - 0.037 12.7 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Chloroa_b-bind PF00504.16 EME27634.1 - 8.8e-12 45.5 0.1 1.2e-11 45.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CDC27 PF09507.5 EME27635.1 - 3e-10 39.9 14.4 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 Myb_DNA-binding PF00249.26 EME27636.1 - 6.4e-13 48.5 0.8 1.2e-12 47.6 0.3 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME27636.1 - 0.00048 20.1 0.9 0.00048 20.1 0.6 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain ubiquitin PF00240.18 EME27637.1 - 0.012 14.9 0.5 0.022 14.1 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin family Longin PF13774.1 EME27638.1 - 1.2e-23 82.4 0.4 2e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.8 EME27638.1 - 0.00024 20.6 2.7 0.00024 20.6 1.9 1.4 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal Rep_fac_C PF08542.6 EME27639.1 - 1e-19 70.2 0.3 2.3e-19 69.1 0.1 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EME27639.1 - 5.4e-15 55.7 0.0 9.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EME27639.1 - 2.5e-13 50.0 0.0 6.2e-11 42.2 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EME27639.1 - 1e-09 37.6 0.0 7.6e-09 34.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EME27639.1 - 3.9e-08 32.6 0.0 1.6e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EME27639.1 - 6e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EME27639.1 - 8e-08 32.2 0.0 1.9e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME27639.1 - 3.5e-07 30.3 0.3 4e-06 26.9 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME27639.1 - 2.9e-06 27.4 0.0 0.00036 20.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME27639.1 - 7.2e-06 25.6 0.2 0.084 12.2 0.0 2.6 2 1 0 3 3 3 2 AAA-like domain AAA_19 PF13245.1 EME27639.1 - 1.6e-05 24.5 0.0 4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EME27639.1 - 2.6e-05 23.8 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EME27639.1 - 5.7e-05 22.3 0.1 0.0015 17.7 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EME27639.1 - 0.00021 20.7 1.0 0.00061 19.2 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EME27639.1 - 0.0004 20.1 0.1 0.0017 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EME27639.1 - 0.00087 18.9 0.2 0.0026 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EME27639.1 - 0.00089 18.7 0.0 0.18 11.2 0.0 2.6 1 1 0 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 EME27639.1 - 0.0047 16.6 0.1 0.071 12.8 0.0 2.5 1 1 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EME27639.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EME27639.1 - 0.0095 16.2 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EME27639.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME27639.1 - 0.026 14.8 0.1 0.063 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EME27639.1 - 0.032 13.9 0.2 0.13 11.9 0.1 2.2 2 1 0 2 2 2 0 NACHT domain PhoH PF02562.11 EME27639.1 - 0.033 13.4 0.0 1.7 7.8 0.0 2.5 1 1 1 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EME27639.1 - 0.049 13.1 0.5 0.46 10.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME27639.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME27639.1 - 0.089 13.6 0.1 0.16 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3400 PF11880.3 EME27639.1 - 0.11 11.7 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DUF2075 PF09848.4 EME27639.1 - 0.12 11.3 0.1 0.71 8.7 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EME27639.1 - 0.13 11.0 0.2 11 4.7 0.1 2.3 1 1 1 2 2 2 0 ArgK protein Pkinase_Tyr PF07714.12 EME27640.1 - 1.5e-58 197.9 0.0 2.5e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME27640.1 - 2.7e-56 190.5 0.0 4.7e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ACT PF01842.20 EME27640.1 - 0.0065 15.9 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EME27640.1 - 0.046 14.0 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 ACT domain Prefoldin PF02996.12 EME27640.1 - 0.28 10.8 2.8 0.86 9.2 0.6 2.6 1 1 2 3 3 3 0 Prefoldin subunit Rootletin PF15035.1 EME27640.1 - 3.8 7.4 10.2 0.14 12.1 0.2 2.7 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion PMM PF03332.8 EME27641.1 - 1.1e-104 348.8 0.7 1.3e-104 348.6 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EME27641.1 - 3.4e-06 26.8 0.0 1.2e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME27641.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4524 PF15025.1 EME27642.1 - 0.00032 20.2 0.1 0.0046 16.4 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.1 EME27642.1 - 0.031 13.8 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) HSP90 PF00183.13 EME27643.1 - 8.6e-150 499.6 15.6 4.9e-148 493.8 10.8 2.2 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EME27643.1 - 1.2e-14 54.1 0.1 4e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME27643.1 - 2.4e-09 36.9 0.1 5.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3240 PF11582.3 EME27643.1 - 0.025 14.4 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) 2OG-FeII_Oxy PF03171.15 EME27644.1 - 4e-20 71.9 0.0 6.2e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EME27644.1 - 1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DnaJ_CXXCXGXG PF00684.14 EME27645.1 - 0.046 13.7 12.6 6.4 6.9 8.9 2.9 1 1 0 1 1 1 0 DnaJ central domain ICEA PF05315.6 EME27645.1 - 0.068 12.4 1.5 5.6 6.1 0.0 2.1 1 1 1 2 2 2 0 ICEA Protein zf-nanos PF05741.8 EME27645.1 - 1.8 8.6 8.1 15 5.6 5.8 2.2 1 1 1 2 2 2 0 Nanos RNA binding domain LpxB PF02684.10 EME27646.1 - 2.6e-75 253.3 0.2 6.3e-75 252.1 0.2 1.5 1 1 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 EME27646.1 - 0.061 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase LpxB PF02684.10 EME27647.1 - 3.6e-78 262.7 0.0 4.4e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.14 EME27647.1 - 0.058 12.1 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Aminotran_1_2 PF00155.16 EME27648.1 - 1e-64 218.8 0.0 1.1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME27648.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EME27648.1 - 0.00039 19.2 0.0 0.0008 18.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME27648.1 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME27648.1 - 0.01 14.1 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EME27648.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Allinase RRM_1 PF00076.17 EME27649.1 - 2.9e-83 273.5 2.1 7.3e-21 73.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27649.1 - 2.6e-58 193.9 0.8 2e-17 62.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27649.1 - 1.1e-44 150.0 0.2 6.5e-12 45.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EME27649.1 - 1.5e-30 104.6 0.3 1.8e-29 101.1 0.3 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EME27649.1 - 5.8e-09 35.5 0.0 0.11 12.3 0.0 4.5 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EME27649.1 - 2.2e-06 27.3 2.2 0.41 10.4 0.0 4.4 4 0 0 4 4 4 2 Limkain b1 RRM_3 PF08777.6 EME27649.1 - 1e-05 25.3 0.8 1.1 9.1 0.1 4.4 4 0 0 4 4 4 2 RNA binding motif DUF4651 PF15513.1 EME27649.1 - 0.082 12.3 0.0 0.75 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_2 PF04059.7 EME27649.1 - 0.084 12.8 0.1 1.7 8.7 0.0 2.9 4 0 0 4 4 4 0 RNA recognition motif 2 Chalcone PF02431.10 EME27650.1 - 2e-28 99.1 0.0 4.1e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Snf7 PF03357.16 EME27651.1 - 7.7e-38 129.5 21.4 7.7e-38 129.5 14.8 1.3 2 0 0 2 2 2 1 Snf7 Ribosomal_S13_N PF08069.7 EME27651.1 - 0.045 13.5 0.6 0.13 12.1 0.4 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Robl_LC7 PF03259.12 EME27651.1 - 0.076 12.5 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain Bromodomain PF00439.20 EME27651.1 - 0.093 12.6 0.5 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Bromodomain Imm39 PF15600.1 EME27651.1 - 0.23 11.2 2.9 0.33 10.7 1.9 1.4 1 1 0 1 1 1 0 Immunity protein 39 DUF1824 PF08854.5 EME27651.1 - 0.52 9.9 5.0 0.74 9.4 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) RVT_N PF13655.1 EME27651.1 - 3.1 7.9 9.2 9.3 6.3 4.9 2.5 2 1 1 3 3 3 0 N-terminal domain of reverse transcriptase RRM_1 PF00076.17 EME27652.1 - 5e-40 134.9 0.0 1.9e-20 72.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27652.1 - 1.8e-22 79.0 0.0 6.8e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME27652.1 - 6e-15 54.8 0.0 1.9e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EME27652.1 - 0.0025 17.2 0.2 0.75 9.3 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.5 EME27652.1 - 0.013 15.4 0.0 8.2 6.4 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Fra10Ac1 PF09725.4 EME27653.1 - 2.6e-42 143.6 3.2 3.6e-42 143.1 2.2 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF947 PF06102.7 EME27653.1 - 0.0019 18.0 0.3 0.0023 17.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Golgin_A5 PF09787.4 EME27653.1 - 0.042 12.3 0.0 0.052 12.0 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SAD_SRA PF02182.12 EME27654.1 - 0.21 10.8 2.5 0.3 10.3 1.8 1.2 1 0 0 1 1 1 0 SAD/SRA domain DUF4661 PF15576.1 EME27654.1 - 0.51 9.9 4.9 0.66 9.5 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Kua-UEV1_localn PF10520.4 EME27656.1 - 6.3e-21 74.8 0.9 1e-20 74.1 0.6 1.3 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF3270 PF11674.3 EME27656.1 - 0.0066 16.4 0.6 0.017 15.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) ACDC PF14733.1 EME27656.1 - 0.052 13.6 0.3 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 AP2-coincident C-terminal Peptidase_C33 PF05412.7 EME27656.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase SIR2 PF02146.12 EME27657.1 - 1.6e-58 197.3 0.0 3.8e-58 196.1 0.0 1.6 2 0 0 2 2 2 1 Sir2 family zf-UBP PF02148.14 EME27657.1 - 6.6e-17 61.3 6.4 6.6e-17 61.3 4.4 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein FYVE_2 PF02318.11 EME27657.1 - 0.04 13.8 4.6 0.23 11.3 0.1 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger TPP_enzyme_M PF00205.17 EME27657.1 - 0.11 12.1 0.0 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ArfGap PF01412.13 EME27657.1 - 0.51 10.1 8.6 0.46 10.2 1.8 2.8 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf EPL1 PF10513.4 EME27658.1 - 4e-15 56.4 1.7 4e-15 56.4 1.2 2.5 3 0 0 3 3 3 1 Enhancer of polycomb-like DUF3667 PF12412.3 EME27659.1 - 0.019 14.2 1.9 0.15 11.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) DUF3023 PF11224.3 EME27659.1 - 0.036 13.7 0.0 0.042 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) PEPCK_ATP PF01293.15 EME27660.1 - 2.8e-194 645.9 0.0 3.6e-194 645.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK PF00821.13 EME27660.1 - 0.027 12.6 0.0 0.041 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase TPT PF03151.11 EME27661.1 - 1.6e-26 92.7 11.2 1.6e-26 92.7 7.7 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME27661.1 - 0.00019 20.5 18.6 0.0022 16.9 12.9 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME27661.1 - 0.00086 19.3 32.7 0.0056 16.7 7.5 3.1 1 1 3 4 4 4 2 EamA-like transporter family WD40 PF00400.27 EME27662.1 - 1.2e-21 75.6 1.4 2.6e-07 30.2 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EME27662.1 - 0.0004 20.2 0.0 0.00084 19.1 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EME27663.1 - 3.3e-40 134.5 1.2 1.2e-08 34.5 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EME27663.1 - 1.1e-24 86.1 0.1 2.9e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Arm PF00514.18 EME27664.1 - 0.082 12.7 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat BCL_N PF04714.8 EME27665.1 - 0.019 14.5 1.2 0.048 13.2 0.9 1.6 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Gar1 PF04410.9 EME27666.1 - 9.4e-37 125.8 0.1 1.2e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RrnaAD PF00398.15 EME27667.1 - 2.5e-60 203.7 0.0 3.3e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EME27667.1 - 8.3e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME27667.1 - 9e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME27667.1 - 6.9e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME27667.1 - 9.1e-05 22.8 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME27667.1 - 0.00026 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EME27667.1 - 0.00057 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME27667.1 - 0.002 18.4 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME27667.1 - 0.0049 16.2 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME27667.1 - 0.005 17.2 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EME27667.1 - 0.058 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 EME27667.1 - 0.065 12.2 0.1 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Met_10 PF02475.11 EME27667.1 - 0.066 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein ArsA_ATPase PF02374.10 EME27667.1 - 0.067 12.2 4.2 3.5 6.5 2.3 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase UPF0020 PF01170.13 EME27667.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PRMT5 PF05185.11 EME27667.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase CobT PF06213.7 EME27667.1 - 0.19 10.8 6.7 0.29 10.2 4.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 EME27667.1 - 0.21 11.0 6.2 0.36 10.3 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin AF1Q PF15017.1 EME27667.1 - 1.8 8.4 6.7 3.3 7.6 4.7 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator HMGL-like PF00682.14 EME27668.1 - 1.6e-80 270.2 0.2 2.6e-80 269.5 0.1 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EME27668.1 - 2.9e-32 111.2 0.7 4.7e-32 110.5 0.5 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Gp_dh_C PF02800.15 EME27669.1 - 8.4e-67 223.5 0.0 1.5e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EME27669.1 - 3.9e-56 189.2 0.1 6.5e-56 188.4 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EME27669.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold OTU PF02338.14 EME27670.1 - 4.4e-18 66.0 0.3 4.4e-18 66.0 0.2 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME27670.1 - 1.2e-05 24.8 0.0 0.014 14.7 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain RRF PF01765.14 EME27671.1 - 1.9e-65 219.3 5.8 1.9e-65 219.3 4.0 1.4 1 1 0 1 1 1 1 Ribosome recycling factor SBP_bac_3 PF00497.15 EME27671.1 - 0.00066 18.9 0.7 0.017 14.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 PilJ PF13675.1 EME27671.1 - 0.02 15.2 1.1 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term YbjQ_1 PF01906.12 EME27671.1 - 0.066 13.6 2.9 0.098 13.0 0.4 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding Apolipoprotein PF01442.13 EME27671.1 - 0.071 12.6 6.9 0.72 9.3 2.0 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EME27671.1 - 0.56 10.6 6.5 3.8 7.9 0.5 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3391 PF11871.3 EME27671.1 - 0.9 9.7 5.5 1.6 8.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF972 PF06156.8 EME27671.1 - 1.2 9.4 8.8 0.61 10.4 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EME27671.1 - 1.7 8.4 6.3 2.7 7.8 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IMD PF08397.6 EME27671.1 - 2 7.6 9.6 0.41 9.9 3.6 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain Spectrin PF00435.16 EME27671.1 - 3.1 8.1 7.9 11 6.3 3.4 2.6 2 1 0 2 2 2 0 Spectrin repeat Rad9 PF04139.8 EME27672.1 - 2.4e-32 112.0 3.6 3.2e-32 111.6 2.5 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EME27672.1 - 4.1e-07 29.2 2.6 0.0016 17.4 1.1 2.2 1 1 0 2 2 2 2 Hus1-like protein TatD_DNase PF01026.16 EME27672.1 - 0.05 12.7 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 TatD related DNase zf-rbx1 PF12678.2 EME27673.1 - 3e-36 123.3 13.0 3.7e-36 123.0 9.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME27673.1 - 1.9e-17 62.8 9.9 2.4e-17 62.5 6.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EME27673.1 - 1.5e-07 31.1 12.1 9.8e-07 28.5 8.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME27673.1 - 0.00095 18.7 11.6 0.013 15.1 8.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27673.1 - 0.0022 17.6 9.8 0.23 11.1 6.9 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME27673.1 - 0.049 13.6 13.0 1.2 9.2 9.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EME27673.1 - 0.08 12.9 8.5 0.36 10.8 6.0 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EME27673.1 - 0.44 10.3 11.7 2.9 7.6 8.1 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME27673.1 - 0.6 9.8 6.9 0.81 9.4 1.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EME27673.1 - 0.75 9.8 9.7 1.7 8.6 6.7 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME27673.1 - 2 8.6 11.1 76 3.5 7.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Amidase PF01425.16 EME27675.1 - 2.4e-87 293.6 0.0 5.1e-87 292.5 0.0 1.5 1 1 0 1 1 1 1 Amidase Tubulin PF00091.20 EME27676.1 - 0.00092 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 EME27676.1 - 0.0029 17.0 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain NAD_binding_1 PF00175.16 EME27677.1 - 4.9e-15 56.0 0.0 8.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EME27677.1 - 0.023 14.6 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EME27678.1 - 6.1e-15 55.7 0.0 9.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EME27678.1 - 0.024 14.5 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Fer4_13 PF13370.1 EME27679.1 - 8.5e-18 64.4 0.2 1.6e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_15 PF13459.1 EME27679.1 - 1.4e-07 31.9 0.1 3.1e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lactamase_B PF00753.22 EME27679.1 - 5.1e-05 23.0 0.1 9.5e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily UQ_con PF00179.21 EME27680.1 - 2.7e-23 81.9 0.0 5.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4 PF00097.20 EME27680.1 - 0.018 14.7 10.2 0.053 13.1 7.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME27680.1 - 0.043 13.6 7.6 0.2 11.5 5.3 2.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EME27680.1 - 0.049 13.6 8.9 0.21 11.6 6.1 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ORF6C PF10552.4 EME27680.1 - 0.095 12.4 1.0 0.94 9.2 0.4 2.6 3 0 0 3 3 3 0 ORF6C domain zf-RING_5 PF14634.1 EME27680.1 - 0.098 12.4 9.9 0.31 10.8 6.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 EME27680.1 - 0.099 12.1 10.2 0.12 11.8 4.9 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain Mito_carr PF00153.22 EME27681.1 - 2.3e-56 187.4 3.7 9.6e-18 63.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM PF01423.17 EME27682.1 - 2.2e-06 27.1 0.9 3.3e-06 26.5 0.2 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 EME27682.1 - 3.7e-05 23.5 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.3 EME27682.1 - 0.017 14.5 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Vps36_ESCRT-II PF11605.3 EME27682.1 - 0.07 12.9 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 SecA_DEAD PF07517.9 EME27682.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain Redoxin PF08534.5 EME27683.1 - 2.8e-28 98.3 0.0 3.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME27683.1 - 4.8e-12 45.6 0.0 6.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Gemini_AL3 PF01407.12 EME27683.1 - 0.03 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Geminivirus AL3 protein DUF2517 PF10725.4 EME27685.1 - 0.08 12.6 1.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Melibiase PF02065.13 EME27686.1 - 8.3e-153 508.7 0.0 1.1e-152 508.3 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF1752 PF08550.5 EME27686.1 - 8.7e-09 34.8 1.7 1.7e-08 33.8 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_hydro_31 PF01055.21 EME27686.1 - 0.00029 19.8 0.0 0.00045 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF187 PF02638.10 EME27686.1 - 0.05 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Melibiase PF02065.13 EME27687.1 - 8.6e-153 508.6 0.0 1.1e-152 508.3 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF1752 PF08550.5 EME27687.1 - 8.9e-09 34.7 1.7 1.8e-08 33.8 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Glyco_hydro_31 PF01055.21 EME27687.1 - 0.0003 19.7 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF187 PF02638.10 EME27687.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Saccharop_dh PF03435.13 EME27688.1 - 6.2e-64 216.3 0.0 1e-63 215.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EME27688.1 - 4.6e-25 88.2 0.0 1.1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EME27688.1 - 1.6e-19 70.0 0.0 4.6e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh_N PF04455.7 EME27688.1 - 4.4e-15 55.6 0.1 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region Semialdhyde_dh PF01118.19 EME27688.1 - 2.8e-05 24.3 0.0 6.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME27688.1 - 0.00016 21.7 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EME27688.1 - 0.0018 18.2 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EME27688.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EME27688.1 - 0.009 16.5 0.0 0.023 15.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 EME27688.1 - 0.047 13.4 0.2 1.3 8.8 0.0 2.5 1 1 1 2 2 2 0 ThiF family NAD_Gly3P_dh_N PF01210.18 EME27688.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aldedh PF00171.17 EME27689.1 - 6.1e-127 423.7 0.0 7.2e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME27689.1 - 0.00038 19.3 0.0 0.00066 18.5 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-RING_2 PF13639.1 EME27690.1 - 9.8e-09 34.9 11.5 1.3e-07 31.3 8.0 2.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME27690.1 - 1.3e-07 31.6 9.0 2.9e-07 30.4 6.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger DUF3592 PF12158.3 EME27690.1 - 3.1e-06 27.0 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) zf-C3HC4 PF00097.20 EME27690.1 - 2.3e-05 23.9 5.9 2.3e-05 23.9 4.1 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27690.1 - 0.0027 17.3 8.1 0.0027 17.3 5.6 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME27690.1 - 0.0032 17.4 15.3 0.0079 16.2 7.0 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME27690.1 - 0.011 15.4 4.6 0.1 12.3 3.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EME27690.1 - 0.41 10.3 14.1 0.34 10.6 6.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME27690.1 - 1 9.2 9.2 2.6 7.9 6.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Polysacc_syn_2C PF08485.5 EME27691.1 - 0.2 11.1 1.9 0.92 9.0 0.1 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal DUF4005 PF13178.1 EME27691.1 - 4.4 7.5 11.3 2.5 8.3 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4005) Rad1 PF02144.11 EME27692.1 - 1.1e-27 96.5 0.0 1.5e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 tRNA-synt_1g PF09334.6 EME27693.1 - 2.2e-115 385.4 0.0 2e-112 375.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EME27693.1 - 7.7e-19 67.1 0.1 2.1e-09 35.9 0.0 3.6 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EME27693.1 - 1.2e-12 47.5 0.0 8.6e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EME27693.1 - 0.0004 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1148 PF06618.6 EME27693.1 - 0.018 14.9 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) DUF4431 PF14485.1 EME27693.1 - 0.029 13.9 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) PC4 PF02229.11 EME27694.1 - 1.1e-20 72.5 0.1 2e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC2_membrane PF01061.19 EME27695.1 - 2.1e-42 144.6 25.4 2.9e-42 144.2 17.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME27695.1 - 2e-28 99.4 0.0 3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME27695.1 - 1.7e-06 28.2 0.3 0.00038 20.4 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME27695.1 - 2.9e-05 23.5 0.1 0.00014 21.2 0.0 2.3 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EME27695.1 - 0.00033 21.4 0.1 0.002 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME27695.1 - 0.0017 17.5 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EME27695.1 - 0.008 15.4 0.1 0.15 11.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 EME27695.1 - 0.0091 15.4 0.1 0.3 10.4 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EME27695.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME27695.1 - 0.03 13.8 0.7 0.13 11.7 0.5 2.1 1 1 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME27695.1 - 0.032 14.3 0.2 0.13 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME27695.1 - 0.033 14.0 0.1 0.17 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 EME27695.1 - 0.034 13.0 15.0 0.097 11.5 10.4 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_16 PF13191.1 EME27695.1 - 0.042 13.8 0.5 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EME27695.1 - 0.046 14.0 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EME27695.1 - 0.047 13.3 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase T2SE PF00437.15 EME27695.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EME27695.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EME27695.1 - 0.11 11.9 0.1 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EME27695.1 - 0.13 12.2 0.0 0.45 10.4 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EME27695.1 - 0.15 11.0 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EME27695.1 - 0.19 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Dynamin family ABC2_membrane_3 PF12698.2 EME27695.1 - 0.7 8.8 30.6 0.095 11.7 17.9 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein NTNH_C PF08470.5 EME27696.1 - 0.027 14.0 0.0 0.028 14.0 0.0 1.0 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Mito_carr PF00153.22 EME27697.1 - 1.5e-63 210.5 0.4 2.2e-22 78.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 EME27698.1 - 3.4e-13 49.0 0.8 2e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME27698.1 - 9.3e-09 34.5 3.8 0.0037 16.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME27698.1 - 1.3e-08 34.0 4.2 0.056 13.3 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME27698.1 - 7.4e-05 23.0 3.1 0.099 13.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME27698.1 - 0.00016 21.5 5.0 0.089 12.7 0.3 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME27698.1 - 0.00024 21.6 4.1 0.11 13.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME27698.1 - 0.0054 17.0 1.7 0.17 12.2 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME27698.1 - 0.011 15.4 3.6 0.7 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 EME27699.1 - 1e-59 198.2 2.6 5.4e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Actin PF00022.14 EME27702.1 - 2.4e-101 339.0 0.0 3.1e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME27702.1 - 0.0012 17.4 0.2 0.029 12.9 0.0 2.5 2 1 0 2 2 2 1 MreB/Mbl protein SLAC1 PF03595.12 EME27703.1 - 4.7e-79 265.4 58.9 5.4e-79 265.2 40.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel YIEGIA PF14045.1 EME27703.1 - 0.39 9.2 2.3 0.73 8.4 1.6 1.4 1 0 0 1 1 1 0 YIEGIA protein F-box PF00646.28 EME27704.1 - 1.5e-07 30.9 2.1 1.5e-07 30.9 1.5 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME27704.1 - 4.5e-07 29.4 3.4 5.9e-06 25.9 1.1 2.7 2 0 0 2 2 2 1 F-box-like ZZ PF00569.12 EME27704.1 - 3.9e-06 26.2 5.5 8.7e-06 25.1 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.15 EME27704.1 - 0.44 10.3 4.7 1.2 8.9 3.2 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MFS_1 PF07690.11 EME27705.1 - 5.1e-31 107.6 37.9 4.6e-26 91.3 4.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME27705.1 - 2.4e-15 56.0 12.2 4.5e-11 41.9 0.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EME27705.1 - 5.8e-06 24.9 7.7 4.2e-05 22.1 0.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EME27705.1 - 1.7e-05 24.5 0.3 0.29 10.9 0.1 2.9 2 0 0 2 2 2 2 MFS_1 like family Inositol_P PF00459.20 EME27706.1 - 5e-54 183.4 0.0 9.1e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family YicC_N PF03755.8 EME27706.1 - 1.4e-31 109.5 0.0 2.6e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 YicC-like family, N-terminal region DUF1732 PF08340.6 EME27706.1 - 5e-28 96.7 0.6 1.5e-27 95.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) Hemerythrin PF01814.18 EME27706.1 - 0.6 10.2 5.3 0.78 9.8 1.1 2.8 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Kinesin PF00225.18 EME27709.1 - 1.2e-110 369.4 0.3 1.2e-110 369.4 0.2 3.1 3 2 2 5 5 5 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 EME27709.1 - 0.00016 21.5 135.3 0.0041 16.9 18.4 9.4 5 2 4 9 9 9 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EME27709.1 - 0.00096 18.7 22.5 0.00096 18.7 15.6 8.1 3 2 4 8 8 8 5 Intermediate filament protein Phage_GP20 PF06810.6 EME27709.1 - 0.0051 16.2 14.8 0.0051 16.2 10.3 8.1 3 1 4 8 8 8 1 Phage minor structural protein GP20 GTP1_OBG PF01018.17 EME27710.1 - 3e-28 98.4 6.3 3.7e-24 85.1 2.7 2.2 1 1 1 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EME27710.1 - 5.6e-21 74.6 0.0 9.7e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1967 PF09269.6 EME27710.1 - 2e-12 46.5 0.2 5.1e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) FeoB_N PF02421.13 EME27710.1 - 6.3e-12 45.0 0.3 1.8e-11 43.5 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF4588 PF15251.1 EME27710.1 - 0.00014 21.9 0.1 0.00022 21.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) ArgK PF03308.11 EME27710.1 - 0.0062 15.3 0.2 1.3 7.7 0.0 2.4 3 0 0 3 3 3 2 ArgK protein GTP_EFTU PF00009.22 EME27710.1 - 0.0084 15.5 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EME27710.1 - 0.019 14.3 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 EME27710.1 - 0.044 13.1 0.0 0.2 11.0 0.0 1.9 1 1 0 1 1 1 0 Ras family Arf PF00025.16 EME27710.1 - 0.06 12.5 0.1 0.26 10.5 0.1 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family Antimicrobial18 PF08130.6 EME27710.1 - 0.068 13.0 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Type A lantibiotic family PduV-EutP PF10662.4 EME27710.1 - 0.085 12.3 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-CCCH PF00642.19 EME27711.1 - 0.002 17.7 1.2 0.0033 17.0 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME27711.1 - 0.32 11.0 6.3 1.3 9.1 4.4 2.1 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EME27712.1 - 0.0013 18.3 1.2 0.0022 17.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FIST PF08495.5 EME27713.1 - 1.7e-20 73.0 0.0 1.6e-19 69.8 0.0 2.3 2 1 0 2 2 2 1 FIST N domain FIST_C PF10442.4 EME27713.1 - 1.1e-05 25.3 0.0 6.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 FIST C domain Hist_deacetyl PF00850.14 EME27714.1 - 3.6e-72 243.2 0.0 4.5e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF1903 PF08991.5 EME27715.1 - 1.3e-08 34.8 8.7 2.1e-08 34.1 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) DUF4094 PF13334.1 EME27715.1 - 0.062 13.6 0.5 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) LolB PF03550.9 EME27715.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB 6PF2K PF01591.13 EME27715.1 - 0.11 11.6 0.5 0.14 11.1 0.3 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CHCH PF06747.8 EME27715.1 - 0.19 11.6 8.6 0.3 11.0 5.4 1.8 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.8 EME27715.1 - 2.5 8.2 9.3 0.48 10.4 2.5 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) RRP7 PF12923.2 EME27716.1 - 2.9e-09 37.0 3.4 5e-09 36.2 2.4 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 EME27716.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME27716.1 - 0.00031 20.3 0.1 0.00057 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C48 PF02902.14 EME27717.1 - 5.7e-10 39.1 0.3 8.9e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vps8 PF12816.2 EME27718.1 - 0.039 13.2 0.1 0.098 11.8 0.0 1.6 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 COX14 PF14880.1 EME27718.1 - 0.79 9.3 0.1 0.79 9.3 0.0 2.3 2 1 0 2 2 2 0 Cytochrome oxidase c assembly Vps8 PF12816.2 EME27719.1 - 0.039 13.2 0.1 0.098 11.8 0.0 1.6 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 COX14 PF14880.1 EME27719.1 - 0.79 9.3 0.1 0.79 9.3 0.0 2.3 2 1 0 2 2 2 0 Cytochrome oxidase c assembly Peptidase_M28 PF04389.12 EME27720.1 - 1.7e-25 89.8 0.0 3.6e-25 88.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EME27720.1 - 0.017 14.6 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EME27720.1 - 0.084 11.6 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase PPR_3 PF13812.1 EME27721.1 - 9.3e-07 28.6 0.8 0.16 12.3 0.0 5.6 6 0 0 6 6 6 2 Pentatricopeptide repeat domain Clathrin PF00637.15 EME27721.1 - 2e-05 24.2 1.1 0.00078 19.0 0.1 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS PPR PF01535.15 EME27721.1 - 2e-05 24.2 0.2 23 5.2 0.0 6.4 7 0 0 7 7 7 0 PPR repeat TPR_19 PF14559.1 EME27721.1 - 0.00095 19.4 4.2 0.0017 18.6 0.9 2.9 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME27721.1 - 0.0014 19.1 1.0 1.4 9.7 0.1 4.7 5 1 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EME27721.1 - 0.0026 17.8 3.2 0.25 11.4 0.2 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EME27721.1 - 0.014 16.0 1.0 0.11 13.2 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME27721.1 - 0.019 14.5 1.4 0.048 13.3 0.2 2.3 2 0 0 2 2 2 0 TPR repeat Imm24 PF15570.1 EME27721.1 - 0.051 13.3 1.0 0.44 10.2 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 24 TPR_2 PF07719.12 EME27721.1 - 0.63 10.0 2.5 12 6.0 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME27721.1 - 1.3 8.7 3.2 58 3.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME27721.1 - 1.4 8.8 4.6 15 5.5 0.2 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF202 PF02656.10 EME27723.1 - 3.4e-14 52.7 1.2 3.4e-14 52.7 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Zip PF02535.17 EME27723.1 - 0.0051 15.8 0.4 1.3 7.9 0.1 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF2755 PF10954.3 EME27723.1 - 0.031 13.9 0.3 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Pex14_N PF04695.8 EME27723.1 - 0.084 12.9 6.0 0.22 11.5 4.2 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1212 PF06738.7 EME27723.1 - 0.099 12.0 3.0 0.17 11.3 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Tetraspannin PF00335.15 EME27723.1 - 0.24 10.6 3.7 0.36 10.0 2.6 1.4 1 0 0 1 1 1 0 Tetraspanin family SdpI PF13630.1 EME27723.1 - 2.7 7.7 7.1 2.8 7.7 3.7 2.0 2 1 0 2 2 2 0 SdpI/YhfL protein family HAD_2 PF13419.1 EME27724.1 - 7.8e-27 94.6 0.0 9.1e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME27724.1 - 2.2e-06 28.2 0.0 1.1e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME27724.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME27724.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Prenyltrans PF00432.16 EME27726.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat CYSTM PF12734.2 EME27726.1 - 1.2 9.2 25.4 89 3.2 17.6 2.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Extensin_2 PF04554.8 EME27726.1 - 3.1 7.7 27.1 7.5 6.5 18.8 1.6 1 1 0 1 1 1 0 Extensin-like region RNA_pol_Rpb6 PF01192.17 EME27727.1 - 6.5e-18 64.2 0.4 6.5e-18 64.2 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 YL1 PF05764.8 EME27727.1 - 0.033 13.8 6.0 0.034 13.7 4.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 EME27727.1 - 0.28 10.4 5.9 0.3 10.3 4.1 1.1 1 0 0 1 1 1 0 SDA1 CTP_transf_2 PF01467.21 EME27728.1 - 2.2e-07 31.0 0.0 6.1e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase Peptidase_M16_C PF05193.16 EME27729.1 - 1.3e-60 204.2 0.0 3.5e-36 124.6 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME27729.1 - 4.6e-33 114.0 0.2 2.9e-22 79.0 0.0 2.7 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Helicase_C_2 PF13307.1 EME27730.1 - 1.1e-52 178.3 0.2 3.5e-52 176.7 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME27730.1 - 3.5e-43 146.9 2.8 4.1e-43 146.8 0.7 2.1 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 EME27730.1 - 5.5e-08 32.8 0.1 0.0003 20.6 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EME27730.1 - 0.0043 16.5 0.0 0.054 12.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Grp1_Fun34_YaaH PF01184.14 EME27731.1 - 5.9e-36 123.7 13.1 7.9e-36 123.3 9.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cpn60_TCP1 PF00118.19 EME27732.1 - 3.7e-157 523.8 4.2 5.3e-155 516.7 2.9 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EME27733.1 - 8.3e-163 542.4 3.1 9.6e-163 542.2 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RusA PF05866.6 EME27733.1 - 0.078 13.3 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA Ribosomal_L10 PF00466.15 EME27734.1 - 1.1e-18 67.0 0.0 1.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF1348 PF07080.6 EME27734.1 - 0.052 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) DUF3025 PF11227.3 EME27734.1 - 0.14 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Prenyltransf PF01255.14 EME27738.1 - 1.7e-73 246.4 0.0 2.1e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4200 PF13863.1 EME27739.1 - 0.0018 18.1 9.3 0.0018 18.1 6.5 3.9 2 2 1 4 4 4 1 Domain of unknown function (DUF4200) BAR_3_WASP_bdg PF10456.4 EME27739.1 - 0.013 14.8 1.2 0.013 14.8 0.8 3.0 2 1 1 3 3 3 0 WASP-binding domain of Sorting nexin protein YqcI_YcgG PF08892.6 EME27739.1 - 0.027 14.0 1.0 0.027 14.0 0.7 2.1 3 0 0 3 3 3 0 YqcI/YcgG family UBA_e1_C PF09358.5 EME27739.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.7 2 2 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain Syntaxin-6_N PF09177.6 EME27739.1 - 0.24 11.8 17.7 2.5 8.5 3.6 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CBFD_NFYB_HMF PF00808.18 EME27739.1 - 0.77 9.8 9.8 5 7.2 0.1 3.3 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCP_MauG PF03150.9 EME27739.1 - 0.99 9.6 11.2 0.55 10.5 2.7 2.5 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Tweety PF04906.8 EME27739.1 - 1.1 7.5 12.2 0.052 11.9 2.6 2.0 2 0 0 2 2 2 0 Tweety COG5 PF10392.4 EME27739.1 - 1.2 9.1 11.8 0.33 10.9 3.5 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF948 PF06103.6 EME27739.1 - 1.5 8.6 9.5 0.95 9.3 1.6 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 EME27739.1 - 1.6 9.0 10.5 1.2 9.4 1.3 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Med11 PF10280.4 EME27739.1 - 4.6 7.3 17.0 3.6e+02 1.1 11.4 3.1 1 1 0 1 1 1 0 Mediator complex protein Reo_sigmaC PF04582.7 EME27739.1 - 5.3 6.1 9.1 4.1 6.4 1.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein COG2 PF06148.6 EME27739.1 - 7.8 6.3 15.4 1.2 9.0 3.9 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-Tim10_DDP PF02953.10 EME27740.1 - 8.1e-20 69.8 1.5 1.1e-19 69.5 1.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phage_min_cap2 PF06152.6 EME27740.1 - 0.014 14.4 0.1 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF1104 PF06518.6 EME27740.1 - 0.026 14.6 0.3 0.041 14.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) PLC-beta_C PF08703.5 EME27740.1 - 0.028 14.1 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 PLC-beta C terminal NatB_MDM20 PF09797.4 EME27740.1 - 0.062 12.0 0.6 0.076 11.7 0.4 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit PolyA_pol_RNAbd PF12627.2 EME27740.1 - 0.084 12.4 0.8 0.15 11.6 0.5 1.4 1 1 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Glyco_hydr_30_2 PF14587.1 EME27741.1 - 1.4e-31 109.8 0.0 2.6e-31 108.9 0.0 1.4 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 EME27741.1 - 2e-05 22.9 0.5 0.1 10.8 0.0 2.9 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Kelch_4 PF13418.1 EME27743.1 - 5.8e-21 74.0 6.2 7.5e-05 22.4 0.0 7.2 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EME27743.1 - 7.7e-21 73.7 0.6 7.4e-07 29.1 0.0 6.5 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EME27743.1 - 2.4e-20 72.0 4.6 0.00032 20.5 0.1 6.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EME27743.1 - 3e-14 52.4 6.8 6e-06 26.2 0.2 5.6 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EME27743.1 - 2.3e-10 39.8 0.3 0.024 14.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif SLAC1 PF03595.12 EME27743.1 - 0.026 13.1 0.3 0.041 12.5 0.2 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Kelch_2 PF07646.10 EME27743.1 - 0.083 12.6 6.1 0.6 9.9 0.0 3.8 3 1 0 3 3 3 0 Kelch motif DUF2977 PF11192.3 EME27743.1 - 0.13 12.0 0.4 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) 2-Hacid_dh_C PF02826.14 EME27744.1 - 8.5e-60 200.9 0.0 1.7e-59 199.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME27744.1 - 9.5e-27 93.0 0.0 1.1e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME27744.1 - 0.00039 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME27744.1 - 0.0018 18.6 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EME27744.1 - 0.0037 17.0 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family Gp_dh_N PF00044.19 EME27744.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME27744.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HEAT_2 PF13646.1 EME27745.1 - 0.029 14.6 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 EME27745.1 - 0.098 12.7 0.1 26 5.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Hexapep PF00132.19 EME27748.1 - 1.8e-30 103.0 10.5 5.2e-08 32.0 0.4 5.8 2 2 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.1 EME27748.1 - 7.2e-08 32.5 0.0 2.4e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.1 EME27748.1 - 2.1e-07 30.3 13.1 0.011 15.2 0.1 6.4 5 2 3 8 8 8 4 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EME27749.1 - 1e-29 100.6 11.4 5.6e-08 31.9 0.4 5.8 2 2 4 7 7 7 7 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.1 EME27749.1 - 7.9e-08 32.4 0.0 2.6e-07 30.7 0.0 1.9 2 1 0 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.1 EME27749.1 - 9.1e-07 28.3 14.9 0.012 15.1 0.1 6.4 5 2 3 8 8 8 4 Hexapeptide repeat of succinyl-transferase Peptidase_S49 PF01343.13 EME27751.1 - 6.8e-58 194.8 0.0 1.4e-35 122.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.18 EME27751.1 - 4.2e-05 23.2 1.0 0.058 13.0 0.1 3.4 3 0 0 3 3 3 2 Clp protease DSX_dimer PF08828.5 EME27751.1 - 0.074 12.6 0.0 4.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Doublesex dimerisation domain TBPIP PF07106.8 EME27752.1 - 1.4e-37 128.8 17.8 2.1e-37 128.2 12.3 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EME27752.1 - 2.1e-08 34.0 15.7 3.7e-08 33.2 10.9 1.5 1 0 0 1 1 1 1 Mnd1 family Penicillinase_R PF03965.11 EME27752.1 - 4e-07 30.1 9.8 1.2e-06 28.5 0.5 3.4 2 1 1 3 3 3 1 Penicillinase repressor HTH_24 PF13412.1 EME27752.1 - 5.3e-06 25.7 2.3 0.0019 17.5 0.0 3.9 3 1 1 4 4 4 1 Winged helix-turn-helix DNA-binding Laminin_II PF06009.7 EME27752.1 - 0.0052 16.5 6.6 0.0052 16.5 4.6 2.2 1 1 1 2 2 2 1 Laminin Domain II HTH_AsnC-type PF13404.1 EME27752.1 - 0.0075 15.7 0.0 0.27 10.7 0.0 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain FlxA PF14282.1 EME27752.1 - 0.014 15.3 11.1 0.034 14.1 7.5 1.9 1 1 0 1 1 1 0 FlxA-like protein PEARLI-4 PF05278.7 EME27752.1 - 0.033 13.5 10.8 0.09 12.1 7.3 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cnd1 PF12717.2 EME27752.1 - 0.04 13.7 4.7 0.51 10.1 0.6 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PA26 PF04636.8 EME27752.1 - 0.067 11.8 5.2 0.083 11.5 3.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2730 PF10805.3 EME27752.1 - 0.077 12.7 5.5 0.39 10.4 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.7 EME27752.1 - 0.084 13.1 0.6 0.084 13.1 0.4 2.7 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 EME27752.1 - 0.092 13.2 7.7 0.17 12.3 0.3 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EME27752.1 - 0.22 9.3 8.5 0.26 9.0 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 EME27752.1 - 0.56 10.5 8.7 0.55 10.5 4.3 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DNA_repr_REX1B PF14966.1 EME27752.1 - 0.6 10.5 11.2 42 4.5 0.0 3.7 2 1 2 4 4 4 0 DNA repair REX1-B DUF3166 PF11365.3 EME27752.1 - 0.62 10.5 7.8 4.5 7.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) DUF342 PF03961.8 EME27752.1 - 0.63 8.3 19.3 2.3 6.5 8.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DivIC PF04977.10 EME27752.1 - 4.2 6.9 15.4 0.16 11.5 2.4 3.2 1 1 2 3 3 3 0 Septum formation initiator GvpK PF05121.7 EME27752.1 - 4.8 7.0 11.9 3.3 7.5 2.5 3.2 2 1 1 3 3 3 0 Gas vesicle protein K LUC7 PF03194.10 EME27752.1 - 5.4 6.4 12.2 9.4 5.6 8.1 1.6 1 1 1 2 2 2 0 LUC7 N_terminus Syntaxin-6_N PF09177.6 EME27752.1 - 6.6 7.2 11.7 10 6.5 4.2 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal HSBP1 PF06825.7 EME27752.1 - 7.4 6.2 7.9 18 5.0 0.2 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 APC10 PF03256.11 EME27753.1 - 2.7e-27 95.6 0.0 3.1e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) AAA PF00004.24 EME27755.1 - 5.8e-41 139.7 0.0 1.4e-40 138.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME27755.1 - 1e-06 28.5 1.6 2.2e-06 27.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME27755.1 - 1.9e-05 24.7 1.4 0.0031 17.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EME27755.1 - 2.1e-05 23.6 0.0 6e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EME27755.1 - 3.5e-05 23.7 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EME27755.1 - 0.00018 21.6 0.3 0.015 15.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EME27755.1 - 0.0013 19.5 0.2 0.0068 17.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EME27755.1 - 0.0041 16.5 0.1 0.0092 15.4 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EME27755.1 - 0.0045 16.8 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME27755.1 - 0.011 15.6 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME27755.1 - 0.012 14.7 0.2 0.034 13.3 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EME27755.1 - 0.019 13.9 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EME27755.1 - 0.023 13.9 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein bZIP_1 PF00170.16 EME27755.1 - 0.033 14.1 3.3 0.082 12.8 2.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor AAA_25 PF13481.1 EME27755.1 - 0.045 13.1 0.3 0.24 10.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EME27755.1 - 0.057 13.0 1.8 0.093 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF972 PF06156.8 EME27755.1 - 0.09 13.1 5.7 0.092 13.1 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_18 PF13238.1 EME27755.1 - 0.093 13.0 0.4 0.61 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME27755.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Atg14 PF10186.4 EME27755.1 - 0.21 10.4 4.5 0.35 9.7 3.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GTSE1_N PF15259.1 EME27755.1 - 0.26 11.2 4.9 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 DUF904 PF06005.7 EME27755.1 - 0.57 10.5 10.1 0.45 10.8 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EME27755.1 - 0.85 9.1 5.7 2.5 7.6 3.9 1.9 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EME27755.1 - 2.7 7.5 8.8 5.8 6.4 6.1 1.5 1 0 0 1 1 1 0 IncA protein DSS1_SEM1 PF05160.8 EME27756.1 - 3.8e-15 55.4 24.1 4.9e-15 55.0 16.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 EME27756.1 - 0.019 14.5 3.8 0.019 14.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF3662 PF12401.3 EME27756.1 - 0.086 13.0 0.3 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2662) Aldedh PF00171.17 EME27757.1 - 5.8e-166 552.3 0.5 6.9e-166 552.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME27757.1 - 0.12 11.6 0.0 0.53 9.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Rad60-SLD_2 PF13881.1 EME27758.1 - 4.9e-12 45.7 0.0 7.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME27758.1 - 1.5e-10 40.3 0.0 2.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EME27758.1 - 0.00042 19.9 0.0 0.007 16.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME27758.1 - 0.065 13.4 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Adaptin_N PF01602.15 EME27759.1 - 3.9e-82 276.2 6.9 6.3e-82 275.5 4.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EME27759.1 - 2.9e-54 182.2 0.0 7.1e-54 181.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EME27759.1 - 3.2e-51 172.6 0.1 5.9e-51 171.8 0.1 1.4 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EME27759.1 - 4.2e-13 49.3 0.6 8.7e-05 22.7 0.1 5.1 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.17 EME27759.1 - 0.003 17.5 0.1 1.3 9.3 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 EME27759.1 - 0.0095 15.7 5.7 0.88 9.3 0.2 3.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.22 EME27760.1 - 3.4e-36 124.5 0.0 7e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EME27760.1 - 7.5e-14 51.0 4.8 1.9e-13 49.7 3.3 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EME27760.1 - 1.5e-13 51.3 3.9 0.004 17.1 0.7 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EME27760.1 - 6.6e-11 41.8 3.5 0.00099 18.3 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EME27760.1 - 3.4e-09 35.9 3.6 3.4e-09 35.9 2.5 3.0 4 0 0 4 4 3 1 4Fe-4S binding domain AAA_15 PF13175.1 EME27760.1 - 6.4e-07 28.7 0.1 2 7.3 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 EME27760.1 - 5.3e-06 25.8 0.2 0.1 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EME27760.1 - 1.8e-05 24.3 3.0 1.8e-05 24.3 2.1 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EME27760.1 - 3.6e-05 23.9 0.1 0.027 14.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EME27760.1 - 4.8e-05 23.0 0.2 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.10 EME27760.1 - 5.7e-05 21.9 0.0 0.0023 16.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EME27760.1 - 6.9e-05 23.1 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME27760.1 - 8.8e-05 22.5 0.0 0.095 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 EME27760.1 - 0.00013 21.7 12.8 0.00013 21.7 8.8 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain DUF258 PF03193.11 EME27760.1 - 0.0002 20.5 2.8 0.25 10.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 MobB PF03205.9 EME27760.1 - 0.00024 20.8 0.4 0.09 12.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EME27760.1 - 0.00027 21.1 0.0 0.36 11.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_2 PF12797.2 EME27760.1 - 0.00031 20.4 2.5 0.00031 20.4 1.7 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_17 PF13207.1 EME27760.1 - 0.00042 21.1 0.5 0.26 12.1 0.1 2.9 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EME27760.1 - 0.00043 20.6 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME27760.1 - 0.00053 19.8 0.2 0.055 13.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 EME27760.1 - 0.00075 19.0 1.3 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_10 PF13237.1 EME27760.1 - 0.00076 19.2 1.5 0.00076 19.2 1.0 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain AAA_28 PF13521.1 EME27760.1 - 0.00092 19.2 0.0 0.37 10.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EME27760.1 - 0.0011 18.7 0.1 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Miro PF08477.8 EME27760.1 - 0.0012 19.3 0.0 0.068 13.6 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein SbcCD_C PF13558.1 EME27760.1 - 0.0013 18.6 0.0 1.1 9.2 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EME27760.1 - 0.0013 18.3 0.1 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_9 PF13187.1 EME27760.1 - 0.0016 18.6 1.9 0.0016 18.6 1.3 2.4 2 1 2 4 4 3 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 EME27760.1 - 0.0025 17.9 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 EME27760.1 - 0.0033 16.9 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_3 PF12798.2 EME27760.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_16 PF13484.1 EME27760.1 - 0.0073 17.0 0.1 0.0073 17.0 0.1 2.8 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Thymidylate_kin PF02223.12 EME27760.1 - 0.01 15.2 0.0 5.1 6.4 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_25 PF13481.1 EME27760.1 - 0.014 14.7 0.0 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME27760.1 - 0.023 14.2 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EME27760.1 - 0.025 14.9 2.4 0.025 14.9 1.6 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain AAA_24 PF13479.1 EME27760.1 - 0.034 13.7 0.3 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME27760.1 - 0.046 13.6 0.2 13 5.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EME27760.1 - 0.059 12.2 0.2 4.4 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 EME27760.1 - 0.074 12.1 0.3 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fer4_7 PF12838.2 EME27760.1 - 0.091 13.1 18.1 0.038 14.3 9.7 2.4 2 1 1 3 3 2 0 4Fe-4S dicluster domain T2SE PF00437.15 EME27760.1 - 0.16 10.8 0.1 0.94 8.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EME27760.1 - 0.16 10.6 0.5 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_13 PF13166.1 EME27760.1 - 0.17 10.3 0.5 0.38 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EME27760.1 - 0.26 11.0 3.8 13 5.4 0.1 3.4 3 1 1 4 4 3 0 NTPase Fer4_8 PF13183.1 EME27760.1 - 0.47 10.5 12.0 0.62 10.1 7.1 2.1 2 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EME27760.1 - 2.4 8.8 8.1 0.11 13.1 0.8 2.3 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_18 PF13746.1 EME27760.1 - 6.5 7.2 11.2 49 4.4 7.8 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain p450 PF00067.17 EME27762.1 - 2.7e-51 174.5 0.2 3.4e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 UCR_14kD PF02271.11 EME27763.1 - 6.1e-20 70.9 0.7 6.5e-20 70.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Tmemb_14 PF03647.8 EME27764.1 - 9.2e-17 61.2 12.6 1.5e-16 60.5 8.7 1.3 1 1 0 1 1 1 1 Transmembrane proteins 14C Abi PF02517.11 EME27764.1 - 0.14 12.3 4.3 0.19 11.8 2.5 1.7 1 1 0 1 1 1 0 CAAX protease self-immunity PLAC8 PF04749.12 EME27764.1 - 0.14 12.6 3.3 0.18 12.3 1.9 1.4 1 1 0 1 1 1 0 PLAC8 family O-antigen_lig PF13425.1 EME27764.1 - 1.5 8.7 10.8 0.56 10.1 5.5 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF4131 PF13567.1 EME27764.1 - 9.4 5.5 13.3 2 7.7 5.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ras PF00071.17 EME27765.1 - 1.7e-62 209.6 0.0 2e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME27765.1 - 3e-22 79.3 0.0 6.8e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME27765.1 - 2.3e-12 46.4 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME27765.1 - 3.8e-06 26.2 0.0 4.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME27765.1 - 1.5e-05 24.5 0.0 7.9e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME27765.1 - 4.8e-05 23.2 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EME27765.1 - 0.0026 17.8 0.0 0.023 14.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EME27765.1 - 0.0074 15.8 0.1 0.014 14.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME27765.1 - 0.016 14.4 0.1 0.043 12.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME27765.1 - 0.06 13.3 0.1 0.15 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EME27765.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1294 PF06961.8 EME27766.1 - 2.3e-21 75.5 1.5 2.7e-21 75.2 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) TauE PF01925.14 EME27766.1 - 0.051 13.0 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE SPT16 PF08644.6 EME27767.1 - 2.2e-45 154.2 0.1 2.2e-45 154.2 0.0 3.0 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 EME27767.1 - 3.2e-28 98.7 0.0 7.1e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.1 EME27767.1 - 1.6e-20 73.2 0.0 4.3e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EME27767.1 - 3.9e-15 55.5 0.1 1.2e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3154 PF11351.3 EME27767.1 - 2.2 8.0 3.5 7.6 6.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Complex1_LYR_1 PF13232.1 EME27768.1 - 1.3e-16 60.5 2.7 1.7e-16 60.1 1.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME27768.1 - 1.1e-15 57.2 1.7 1.6e-15 56.6 1.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EME27768.1 - 0.0041 17.5 2.6 0.0051 17.2 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Pfg27 PF09216.5 EME27768.1 - 0.025 14.1 0.3 0.027 14.0 0.2 1.1 1 0 0 1 1 1 0 Pfg27 FlaG PF03646.10 EME27768.1 - 0.037 14.1 1.0 0.2 11.7 0.7 1.8 2 0 0 2 2 2 0 FlaG protein SURF6 PF04935.7 EME27768.1 - 0.045 13.0 1.5 0.053 12.8 1.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Sp100 PF03172.8 EME27768.1 - 0.16 11.9 0.9 0.4 10.6 0.2 1.8 1 1 1 2 2 2 0 Sp100 domain Mucin PF01456.12 EME27769.1 - 0.007 16.1 0.3 0.0093 15.7 0.2 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein NfrA_C PF13283.1 EME27769.1 - 0.088 12.1 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term DUF3753 PF12575.3 EME27769.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ATP-synt_ab PF00006.20 EME27770.1 - 4e-62 209.5 0.0 6.8e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME27770.1 - 4.5e-26 91.5 0.1 7.3e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME27770.1 - 1.8e-24 85.6 1.5 3.8e-24 84.6 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EME27770.1 - 0.011 14.9 0.3 0.021 13.9 0.2 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EME27770.1 - 0.022 14.1 0.1 0.054 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EME27770.1 - 0.074 12.7 0.3 4.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME27770.1 - 0.078 12.9 0.1 0.41 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EME27770.1 - 0.082 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EME27770.1 - 0.09 12.4 0.4 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EME27770.1 - 0.12 12.5 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME27770.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EME27770.1 - 0.2 10.9 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ATP-synt_DE_N PF02823.11 EME27771.1 - 6.7e-23 80.2 0.1 1.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain NARP1 PF12569.3 EME27772.1 - 9.7e-134 446.9 18.4 2e-133 445.9 7.6 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EME27772.1 - 1.4e-13 51.1 5.4 0.0002 21.9 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME27772.1 - 2.7e-12 46.1 15.2 6.8e-06 25.6 0.1 5.5 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 EME27772.1 - 4.9e-12 44.7 19.4 2.7e-05 23.7 0.5 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME27772.1 - 9.7e-11 41.3 2.0 0.036 14.6 0.3 6.9 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME27772.1 - 1.1e-09 38.4 6.0 0.007 16.6 1.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME27772.1 - 1.9e-08 34.0 0.9 0.045 13.6 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME27772.1 - 6.9e-08 32.3 15.4 0.011 15.7 0.4 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME27772.1 - 4.9e-06 26.3 1.9 0.6 10.4 0.0 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME27772.1 - 7.1e-06 25.8 4.0 0.04 13.7 0.2 4.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EME27772.1 - 2.6e-05 24.3 10.2 0.24 11.9 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME27772.1 - 6.9e-05 22.2 24.6 0.0046 16.5 0.9 6.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME27772.1 - 0.00056 19.5 12.0 0.019 14.6 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME27772.1 - 0.00086 18.9 8.1 0.051 13.3 0.1 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 EME27772.1 - 0.048 13.4 0.7 3.6 7.4 0.0 3.0 2 1 1 3 3 2 0 Rapsyn N-terminal myristoylation and linker region Tox-HNH-HHH PF15637.1 EME27773.1 - 3 7.6 6.7 6.2 6.6 0.0 3.6 4 0 0 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif RHD3 PF05879.7 EME27774.1 - 4.6e-159 530.7 24.5 3e-158 528.0 17.0 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EME27774.1 - 1.1e-05 24.6 0.3 3.9e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EME27774.1 - 5.1e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME27774.1 - 9.9e-05 22.2 0.0 0.00035 20.4 0.0 2.0 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EME27774.1 - 0.00074 20.0 0.2 0.0083 16.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EME27774.1 - 0.0095 15.9 0.0 0.038 13.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EME27774.1 - 0.082 13.2 0.0 0.52 10.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EME27774.1 - 0.77 10.5 3.1 2.1 9.1 0.0 3.1 3 2 0 3 3 3 0 AAA domain AAA_2 PF07724.9 EME27775.1 - 3.1e-43 147.6 0.0 4.8e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EME27775.1 - 1.2e-15 57.8 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EME27775.1 - 5.9e-14 51.7 0.2 1.4e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EME27775.1 - 1.6e-06 27.8 0.0 6.1e-06 25.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME27775.1 - 4.2e-06 26.9 0.1 2e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME27775.1 - 9.8e-06 26.3 0.0 2.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME27775.1 - 2.7e-05 23.3 0.1 0.00054 19.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME27775.1 - 3.5e-05 23.6 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EME27775.1 - 7.6e-05 22.7 0.0 0.00035 20.6 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EME27775.1 - 0.0001 21.5 0.0 0.021 14.0 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME27775.1 - 0.00016 21.1 0.0 0.002 17.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain T2SE PF00437.15 EME27775.1 - 0.00017 20.5 0.1 0.00032 19.6 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EME27775.1 - 0.0004 20.4 0.0 0.0012 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.18 EME27775.1 - 0.00067 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_33 PF13671.1 EME27775.1 - 0.00075 19.4 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME27775.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 EME27775.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EME27775.1 - 0.0019 17.7 0.1 0.0078 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EME27775.1 - 0.0031 17.6 0.0 0.0096 16.0 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EME27775.1 - 0.0032 17.7 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EME27775.1 - 0.0039 17.4 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter IPT PF01745.11 EME27775.1 - 0.0054 15.9 0.3 0.065 12.3 0.1 2.3 2 0 0 2 2 2 1 Isopentenyl transferase TIP49 PF06068.8 EME27775.1 - 0.0065 15.2 0.2 0.015 14.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus TrwB_AAD_bind PF10412.4 EME27775.1 - 0.0084 14.7 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 EME27775.1 - 0.0084 15.8 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EME27775.1 - 0.0088 16.3 0.1 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EME27775.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME27775.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EME27775.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EME27775.1 - 0.015 14.7 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EME27775.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EME27775.1 - 0.018 14.7 0.0 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EME27775.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EME27775.1 - 0.036 13.8 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 EME27775.1 - 0.038 13.1 0.2 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DEAD PF00270.24 EME27775.1 - 0.04 13.4 0.1 0.14 11.6 0.0 1.8 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.6 EME27775.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EME27775.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AMNp_N PF10423.4 EME27775.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus SRPRB PF09439.5 EME27775.1 - 0.06 12.5 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SKI PF01202.17 EME27775.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase KaiC PF06745.8 EME27775.1 - 0.079 12.0 1.3 0.53 9.3 0.1 2.5 2 1 1 3 3 3 0 KaiC DUF1654 PF07867.6 EME27779.1 - 0.067 12.5 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Tweety PF04906.8 EME27782.1 - 9e-05 21.0 8.5 0.00016 20.1 5.9 1.4 1 1 0 1 1 1 1 Tweety TMEM52 PF14979.1 EME27782.1 - 0.05 13.5 4.0 0.42 10.4 0.5 2.4 2 0 0 2 2 2 0 Transmembrane 52 Orthoreo_P10 PF07204.6 EME27782.1 - 0.083 12.6 0.4 0.26 11.0 0.3 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Herpes_LMP1 PF05297.6 EME27782.1 - 1 8.2 6.4 1.7 7.4 4.5 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tim44 PF04280.10 EME27784.1 - 9.8e-38 129.4 0.8 3.7e-37 127.5 0.1 2.2 2 1 0 2 2 2 1 Tim44-like domain WD40 PF00400.27 EME27785.1 - 4.6e-52 172.1 6.7 4e-10 39.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME27785.1 - 8.4e-06 25.6 0.0 0.0006 19.5 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EME27785.1 - 1.1e-05 25.0 0.6 5.7e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EME27785.1 - 6.9e-05 21.7 0.1 0.67 8.6 0.0 3.7 1 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EME27785.1 - 0.00021 19.6 0.0 0.00099 17.5 0.0 1.9 1 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1513 PF07433.6 EME27785.1 - 0.00034 19.6 0.0 0.16 10.7 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.9 EME27785.1 - 0.0031 16.3 0.1 0.96 8.1 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Nbas_N PF15492.1 EME27785.1 - 0.024 13.7 1.2 2.7 7.0 0.0 2.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EME27785.1 - 0.043 11.9 1.2 1.7 6.6 0.2 2.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.7 EME27785.1 - 0.071 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Mito_carr PF00153.22 EME27786.1 - 8e-59 195.3 2.8 1.3e-19 69.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 EME27786.1 - 0.16 11.7 0.0 15 5.4 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family TauE PF01925.14 EME27786.1 - 0.96 8.8 5.2 3.5 7.0 3.0 2.3 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Thioredoxin PF00085.15 EME27787.1 - 4.5e-15 55.2 0.0 7.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME27787.1 - 5.6e-05 23.1 0.7 0.0027 17.7 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin-like ERp29_N PF07912.8 EME27787.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EME27787.1 - 0.051 13.1 0.2 0.39 10.2 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin Thioredoxin_2 PF13098.1 EME27787.1 - 0.065 13.4 0.3 0.56 10.4 0.0 2.5 3 1 0 3 3 3 0 Thioredoxin-like domain DcuC PF03606.10 EME27787.1 - 0.076 11.2 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier AhpC-TSA PF00578.16 EME27787.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF3769 PF12600.3 EME27788.1 - 3e-10 39.4 0.0 2.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3769) E1_dh PF00676.15 EME27789.1 - 4.4e-108 360.5 0.0 5.4e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EME27789.1 - 0.0006 18.8 0.2 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Asp PF00026.18 EME27790.1 - 1.1e-45 156.2 0.5 1.6e-45 155.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME27790.1 - 4.4e-13 49.0 0.0 9.2e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EME27790.1 - 0.00016 22.1 0.1 0.23 11.9 0.0 3.3 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EME27790.1 - 0.0041 16.9 0.0 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Rhodanese PF00581.15 EME27791.1 - 7e-20 71.4 0.0 8.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S41 PF03572.13 EME27792.1 - 1.2e-39 135.4 0.0 2.3e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.1 EME27792.1 - 2.1e-07 30.7 0.1 7.2e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 EME27792.1 - 0.00011 22.2 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Response_reg PF00072.19 EME27792.1 - 0.1 12.6 0.0 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain Myb_DNA-binding PF00249.26 EME27793.1 - 3.8e-13 49.2 0.5 8.2e-13 48.1 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RST PF12174.3 EME27793.1 - 4.4e-06 26.3 0.6 4.4e-06 26.3 0.4 2.6 3 0 0 3 3 3 1 RCD1-SRO-TAF4 (RST) plant domain Myb_DNA-bind_6 PF13921.1 EME27793.1 - 6.9e-06 26.0 0.6 3.7e-05 23.7 0.4 2.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain AAA_12 PF13087.1 EME27794.1 - 2.2e-61 206.7 0.0 4.4e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME27794.1 - 5.3e-52 176.7 0.4 1.4e-51 175.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME27794.1 - 5.4e-11 42.0 0.1 1.3e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EME27794.1 - 6.1e-09 35.7 0.0 0.053 13.0 0.0 3.7 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EME27794.1 - 2.8e-07 30.3 0.0 4.3e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EME27794.1 - 3.5e-05 23.2 3.2 4.2e-05 22.9 0.0 2.9 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_33 PF13671.1 EME27794.1 - 0.00039 20.3 0.0 0.22 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EME27794.1 - 0.00058 20.0 0.1 0.05 13.7 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME27794.1 - 0.00087 19.3 0.0 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EME27794.1 - 0.0041 16.5 0.0 0.035 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 EME27794.1 - 0.007 16.2 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 EME27794.1 - 0.008 16.2 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_18 PF13238.1 EME27794.1 - 0.011 16.0 0.2 0.12 12.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Helicase_RecD PF05127.9 EME27794.1 - 0.013 15.1 0.4 0.071 12.7 0.0 2.4 3 0 0 3 3 3 0 Helicase AAA PF00004.24 EME27794.1 - 0.02 15.0 0.0 0.094 12.9 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EME27794.1 - 0.024 14.0 0.0 0.063 12.7 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 EME27794.1 - 0.031 13.2 0.0 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.9 EME27794.1 - 0.036 13.8 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF853 PF05872.7 EME27794.1 - 0.043 12.1 0.0 0.076 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_17 PF13207.1 EME27794.1 - 0.064 14.0 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME27794.1 - 0.1 11.6 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EME27795.1 - 3.4e-46 155.9 0.5 1.1e-22 80.2 0.0 3.0 3 1 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EME27795.1 - 2.9e-24 84.8 0.1 6.7e-24 83.6 0.1 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 EME27795.1 - 1.9e-20 72.7 0.3 2.3e-10 39.9 0.0 3.5 4 0 0 4 4 3 2 Ferrous iron transport protein B Miro PF08477.8 EME27795.1 - 6.3e-17 62.1 4.9 1.2e-07 32.1 0.0 4.0 3 1 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 EME27795.1 - 1.1e-12 47.8 3.3 3.8e-06 26.4 0.1 4.5 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EME27795.1 - 1.2e-10 41.5 7.7 0.0043 16.8 0.0 5.0 3 2 2 5 5 5 2 Dynamin family Ras PF00071.17 EME27795.1 - 6e-10 38.7 0.1 0.021 14.1 0.0 4.0 3 1 0 3 3 3 3 Ras family DUF258 PF03193.11 EME27795.1 - 7.1e-10 38.3 0.3 7.6e-06 25.2 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arf PF00025.16 EME27795.1 - 1.1e-08 34.5 2.3 0.092 11.9 0.0 4.5 4 1 0 4 4 4 3 ADP-ribosylation factor family AIG1 PF04548.11 EME27795.1 - 5.1e-06 25.7 8.0 0.0012 18.0 0.1 3.5 3 1 0 4 4 4 2 AIG1 family ABC_tran PF00005.22 EME27795.1 - 9.7e-06 25.9 1.1 0.0039 17.4 0.0 3.3 2 1 1 3 3 3 1 ABC transporter AAA_18 PF13238.1 EME27795.1 - 2.1e-05 24.8 2.5 0.017 15.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EME27795.1 - 5.7e-05 23.9 0.0 0.068 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME27795.1 - 0.00012 21.7 0.2 0.026 14.2 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EME27795.1 - 0.00015 21.2 0.5 4.6 6.7 0.0 4.1 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EME27795.1 - 0.00042 20.4 0.1 0.093 12.8 0.0 3.4 2 2 1 3 3 2 1 AAA domain ArgK PF03308.11 EME27795.1 - 0.0013 17.6 0.0 0.035 12.8 0.0 2.5 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EME27795.1 - 0.0022 18.1 0.0 2 8.6 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.1 EME27795.1 - 0.0037 16.8 0.1 4.3 6.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DAP3 PF10236.4 EME27795.1 - 0.0056 15.6 0.0 0.45 9.3 0.0 2.6 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 EME27795.1 - 0.0063 15.9 1.3 1.5 8.2 0.0 3.1 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME27795.1 - 0.0063 16.0 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EME27795.1 - 0.009 15.9 0.1 0.64 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EME27795.1 - 0.012 14.8 0.0 5.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EME27795.1 - 0.014 15.0 2.0 0.18 11.4 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_10 PF12846.2 EME27795.1 - 0.016 14.6 0.3 1.2 8.5 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 EME27795.1 - 0.022 14.7 0.0 0.8 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME27795.1 - 0.031 13.9 2.0 0.99 9.0 0.0 3.1 3 1 1 4 4 3 0 Archaeal ATPase AAA_25 PF13481.1 EME27795.1 - 0.035 13.4 0.0 14 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EME27795.1 - 0.048 13.1 0.6 0.21 11.0 0.0 2.4 4 0 0 4 4 2 0 FtsK/SpoIIIE family Nuc_deoxyrib_tr PF05014.10 EME27795.1 - 0.23 11.3 1.5 0.85 9.5 0.0 2.6 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase AAA_16 PF13191.1 EME27795.1 - 0.56 10.1 3.8 6.6 6.6 1.3 3.6 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_M17 PF00883.16 EME27796.1 - 3.8e-122 407.0 0.3 4.8e-122 406.7 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EME27796.1 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Lipase_3 PF01764.20 EME27797.1 - 3.3e-27 94.8 0.0 6.3e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Frag1 PF10277.4 EME27797.1 - 0.012 15.1 0.1 0.026 13.9 0.1 1.6 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Sugar_tr PF00083.19 EME27798.1 - 7.3e-31 107.2 30.8 4.2e-17 61.8 4.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME27798.1 - 4.2e-25 88.2 67.9 7.3e-18 64.3 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1084 PF06454.6 EME27798.1 - 0.0017 17.4 2.2 0.0033 16.5 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) SSB PF00436.20 EME27799.1 - 1.5e-06 27.9 0.0 1.8e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Surp PF01805.15 EME27800.1 - 9.5e-38 127.6 3.6 2.4e-19 68.7 0.2 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.3 EME27800.1 - 3.3e-31 108.5 14.2 3.3e-31 108.5 9.9 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.18 EME27800.1 - 0.005 16.2 0.0 0.017 14.4 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Thioredoxin PF00085.15 EME27801.1 - 1.2e-23 82.7 0.0 1.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME27801.1 - 1.9e-08 34.5 0.0 9.6e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME27801.1 - 1.4e-05 25.1 0.0 0.019 15.0 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like HyaE PF07449.6 EME27801.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 EME27801.1 - 0.019 14.7 0.1 0.058 13.2 0.0 1.9 2 1 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME27801.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like TraF PF13728.1 EME27801.1 - 0.051 13.0 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Trypsin_2 PF13365.1 EME27802.1 - 0.054 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain PGM_PMM_III PF02880.11 EME27803.1 - 4.6e-14 52.4 0.0 8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 EME27803.1 - 8.8e-07 28.4 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Antimicrobial_3 PF08025.6 EME27803.1 - 0.072 12.8 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Spider antimicrobial peptide DUF1995 PF09353.5 EME27804.1 - 3.2e-24 85.7 0.0 5.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Tnp_zf-ribbon_2 PF13842.1 EME27804.1 - 0.14 12.5 1.4 0.43 11.0 0.9 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon ClpS PF02617.12 EME27805.1 - 5.2e-12 45.3 0.2 9.2e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DNA_gyraseB PF00204.20 EME27806.1 - 5.1e-48 162.5 0.2 8e-48 161.9 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.16 EME27806.1 - 1.6e-27 95.0 0.2 5.9e-27 93.2 0.1 2.1 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.17 EME27806.1 - 5.4e-27 93.6 0.0 1.5e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EME27806.1 - 5.9e-16 58.1 0.1 1.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME27806.1 - 5.1e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 EME27806.1 - 0.0057 16.6 0.1 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain SRP54 PF00448.17 EME27807.1 - 3.5e-27 95.1 0.1 1.2e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EME27807.1 - 9.6e-26 90.0 7.3 1.5e-25 89.4 2.5 2.7 3 0 0 3 3 3 1 Signal peptide binding domain Mmp37 PF09139.6 EME27807.1 - 0.025 13.6 2.5 0.036 13.0 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Atg14 PF10186.4 EME27807.1 - 2.6 6.8 7.1 4.1 6.2 4.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SRP54 PF00448.17 EME27808.1 - 2.2e-20 72.9 0.5 4.6e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EME27808.1 - 1.7e-09 37.6 2.8 2.7e-09 36.9 1.9 1.4 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_14 PF13173.1 EME27808.1 - 0.00022 21.1 0.2 0.00071 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME27808.1 - 0.00058 19.5 0.1 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EME27808.1 - 0.001 18.9 3.0 0.0011 18.8 0.8 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EME27808.1 - 0.0013 18.7 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EME27808.1 - 0.0015 18.1 1.5 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EME27808.1 - 0.0018 18.1 0.1 0.0046 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EME27808.1 - 0.0018 17.5 0.2 0.0051 16.0 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EME27808.1 - 0.0027 17.8 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME27808.1 - 0.0035 16.3 1.3 0.0056 15.6 0.9 1.4 1 1 0 1 1 1 1 Type II/IV secretion system protein SRPRB PF09439.5 EME27808.1 - 0.0079 15.4 3.5 0.14 11.3 0.0 2.6 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EME27808.1 - 0.01 16.3 0.4 0.086 13.3 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EME27808.1 - 0.017 14.1 1.1 0.045 12.8 0.1 2.0 2 1 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EME27808.1 - 0.018 13.7 0.7 0.077 11.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EME27808.1 - 0.02 15.2 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EME27808.1 - 0.022 15.6 0.0 0.061 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EME27808.1 - 0.027 13.1 1.4 0.038 12.6 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.10 EME27808.1 - 0.042 13.5 2.0 4.9 6.8 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA PF00004.24 EME27808.1 - 0.057 13.6 0.3 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Laminin_II PF06009.7 EME27808.1 - 0.064 13.0 1.2 0.098 12.4 0.8 1.3 1 0 0 1 1 1 0 Laminin Domain II PduV-EutP PF10662.4 EME27808.1 - 0.082 12.3 1.1 0.13 11.7 0.2 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EME27808.1 - 0.085 13.1 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EME27808.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-RING_2 PF13639.1 EME27809.1 - 1.7e-11 43.7 4.7 2.7e-11 43.1 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME27809.1 - 2e-10 40.6 0.8 3.3e-10 39.9 0.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME27809.1 - 6.4e-08 32.3 0.4 1.1e-07 31.5 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EME27809.1 - 1.3e-07 31.5 5.5 2e-07 30.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME27809.1 - 6.7e-07 28.8 4.9 1.1e-06 28.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27809.1 - 1.2e-06 28.1 2.5 1.8e-06 27.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME27809.1 - 1e-05 25.1 1.8 1.7e-05 24.3 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME27809.1 - 0.0056 16.3 1.2 0.038 13.7 0.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EME27809.1 - 0.0066 16.3 5.7 0.056 13.4 4.0 2.3 1 1 1 2 2 2 1 FANCL C-terminal domain zf-Nse PF11789.3 EME27809.1 - 0.0088 15.5 1.5 0.016 14.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EME27809.1 - 0.053 13.3 6.1 0.42 10.5 4.7 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING YdjO PF14169.1 EME27809.1 - 0.14 11.5 0.4 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Cold-inducible protein YdjO RINGv PF12906.2 EME27809.1 - 0.22 11.5 3.1 0.46 10.5 2.1 1.6 1 0 0 1 1 1 0 RING-variant domain DZR PF12773.2 EME27809.1 - 0.24 11.2 3.1 5.3 6.9 0.3 2.3 1 1 2 3 3 3 0 Double zinc ribbon zf-NADH-PPase PF09297.6 EME27809.1 - 0.73 9.4 0.0 0.73 9.4 0.0 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain PHD PF00628.24 EME27809.1 - 1.1 8.9 4.4 3.6 7.3 3.0 1.9 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EME27809.1 - 1.2 8.9 5.1 5.3 6.8 3.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EME27809.1 - 2.3 7.8 7.0 8.6 6.0 0.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EME27809.1 - 3.7 7.1 6.1 21 4.7 2.7 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SET PF00856.23 EME27810.1 - 2.8e-25 89.4 0.2 2.8e-25 89.4 0.2 2.7 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.17 EME27810.1 - 3.5e-08 32.9 0.0 1.4e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27810.1 - 2.3e-05 24.2 0.0 0.0062 16.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 EME27811.1 - 2.7e-25 89.5 0.3 2.7e-25 89.5 0.2 2.7 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.17 EME27811.1 - 3.3e-08 33.0 0.0 1.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME27811.1 - 2.1e-05 24.4 0.0 0.006 16.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LSM PF01423.17 EME27812.1 - 7.4e-07 28.6 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 LSM domain MRP-L47 PF06984.8 EME27813.1 - 1.7e-18 66.3 1.3 1.7e-18 66.3 0.9 1.8 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) SF3b1 PF08920.5 EME27814.1 - 3.6e-35 121.1 8.7 4.9e-34 117.4 6.0 2.4 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EME27814.1 - 2.7e-13 50.0 3.4 0.00021 21.4 0.0 7.4 6 2 3 9 9 9 3 HEAT repeats HEAT PF02985.17 EME27814.1 - 1.9e-12 46.1 1.4 0.22 11.6 0.0 8.6 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EME27814.1 - 3.9e-10 39.8 0.1 0.47 11.0 0.0 8.5 8 1 1 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME27814.1 - 6.7e-05 23.2 0.8 3 8.2 0.0 5.2 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EME27814.1 - 0.00011 21.9 0.5 9 6.2 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EME27814.1 - 0.0027 16.5 0.0 0.31 9.7 0.0 2.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EME27814.1 - 0.0048 15.2 0.7 0.1 10.8 0.0 3.1 2 2 0 3 3 3 1 Adaptin N terminal region TIP120 PF08623.5 EME27814.1 - 0.0054 16.3 0.1 0.027 14.0 0.0 2.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) CTD PF12815.2 EME27814.1 - 1.4 9.3 3.3 5.8 7.3 2.3 2.0 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 ABC1 PF03109.11 EME27815.1 - 7.4e-21 74.3 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EME27815.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EME27815.1 - 0.0048 16.1 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 EME27815.1 - 0.026 13.6 0.1 0.21 10.7 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain HipA_C PF07804.7 EME27815.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 HipA-like C-terminal domain YrbL-PhoP_reg PF10707.4 EME27815.1 - 0.072 12.4 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ABC1 PF03109.11 EME27816.1 - 7.4e-21 74.3 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EME27816.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EME27816.1 - 0.0048 16.1 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 EME27816.1 - 0.026 13.6 0.1 0.21 10.7 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain HipA_C PF07804.7 EME27816.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 HipA-like C-terminal domain YrbL-PhoP_reg PF10707.4 EME27816.1 - 0.072 12.4 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DAO PF01266.19 EME27817.1 - 1.4e-10 40.6 0.9 2.7e-09 36.4 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME27817.1 - 2.3e-10 40.3 0.2 1e-09 38.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME27817.1 - 2.1e-07 30.3 3.3 0.006 15.7 0.1 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EME27817.1 - 3e-07 29.7 0.1 8.9e-07 28.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EME27817.1 - 1.5e-05 24.2 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME27817.1 - 8.2e-05 21.6 2.4 8.2e-05 21.6 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EME27817.1 - 9.2e-05 21.0 0.5 0.00065 18.2 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EME27817.1 - 0.00033 19.8 0.2 0.00049 19.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME27817.1 - 0.00045 20.5 0.5 0.0011 19.3 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME27817.1 - 0.0005 19.0 0.7 0.0035 16.2 0.5 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME27817.1 - 0.00053 19.9 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME27817.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EME27817.1 - 0.01 14.1 0.0 0.14 10.4 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 EME27817.1 - 0.024 13.3 0.6 0.049 12.2 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EME27817.1 - 0.083 12.2 0.1 0.29 10.4 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 EME27818.1 - 1.6e-75 253.6 0.0 1.8e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27818.1 - 4.3e-31 107.9 0.0 5.6e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME27818.1 - 0.00027 20.7 0.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME27818.1 - 0.0024 16.8 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EME27818.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_9 PF14604.1 EME27819.1 - 2.6e-17 62.1 0.1 4.8e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME27819.1 - 1.6e-16 59.3 0.1 3.1e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EME27819.1 - 1.3e-11 43.8 0.0 2.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_1 PF00036.27 EME27820.1 - 2.4e-36 120.2 15.7 2.7e-10 38.7 0.3 5.1 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EME27820.1 - 6.5e-32 109.4 6.1 5.8e-16 58.3 0.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EME27820.1 - 3.1e-31 106.7 11.9 4.5e-16 58.2 0.3 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EME27820.1 - 1.5e-27 92.9 6.1 2.7e-08 32.9 0.1 4.8 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EME27820.1 - 3.8e-22 76.5 10.7 9.4e-06 24.7 0.1 5.4 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EME27820.1 - 4.2e-12 45.8 0.2 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EME27820.1 - 3.9e-08 33.3 0.1 0.0066 16.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EME27820.1 - 1.2e-07 31.3 3.1 0.00022 20.8 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 EME27820.1 - 6.2e-05 22.7 1.1 0.084 12.6 0.1 2.7 2 1 1 3 3 3 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.5 EME27820.1 - 0.00017 21.5 1.3 0.0026 17.6 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EME27820.1 - 0.001 18.6 0.6 0.11 12.0 0.0 2.9 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.11 EME27820.1 - 0.006 16.5 1.1 0.67 9.9 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb4 MutL_C PF08676.6 EME27820.1 - 0.0096 15.5 0.4 0.078 12.5 0.1 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain Toprim_2 PF13155.1 EME27820.1 - 0.046 14.0 1.4 2 8.8 0.1 2.6 1 1 2 3 3 3 0 Toprim-like DUF3349 PF11829.3 EME27820.1 - 0.065 13.6 0.2 14 6.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) Tenui_NCP PF04876.7 EME27820.1 - 0.095 12.2 0.1 0.55 9.7 0.0 2.0 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein Toprim PF01751.17 EME27820.1 - 0.097 12.6 0.1 2 8.4 0.0 2.2 1 1 1 2 2 2 0 Toprim domain EF-hand_1 PF00036.27 EME27821.1 - 9.5e-42 137.1 12.9 2.6e-10 38.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EME27821.1 - 5e-36 122.6 5.3 3.5e-20 71.9 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EME27821.1 - 1e-32 111.4 12.5 9.2e-16 57.2 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EME27821.1 - 1.2e-31 105.7 6.3 6.9e-10 37.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EME27821.1 - 5e-27 92.0 9.0 1.3e-06 27.4 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EME27821.1 - 2.7e-14 52.7 0.1 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EME27821.1 - 7.4e-10 38.8 0.2 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EME27821.1 - 2.7e-07 30.2 2.9 0.00064 19.4 0.1 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EME27821.1 - 1.5e-06 28.0 1.7 2e-05 24.5 0.3 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EME27821.1 - 9.6e-05 22.1 2.9 0.034 13.8 0.1 2.6 1 1 2 3 3 3 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EME27821.1 - 0.00088 18.8 0.6 0.097 12.2 0.0 2.9 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) MutL_C PF08676.6 EME27821.1 - 0.0071 15.9 0.2 0.07 12.7 0.0 2.0 1 1 0 2 2 2 1 MutL C terminal dimerisation domain RNA_pol_Rpb4 PF03874.11 EME27821.1 - 0.0081 16.1 1.5 0.7 9.9 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb4 EAP30 PF04157.11 EME27821.1 - 0.0091 15.1 0.0 1.8 7.6 0.0 2.1 1 1 1 2 2 2 2 EAP30/Vps36 family Toprim_2 PF13155.1 EME27821.1 - 0.021 15.1 2.5 1.8 8.9 0.1 2.9 1 1 1 2 2 2 0 Toprim-like DUF3349 PF11829.3 EME27821.1 - 0.03 14.7 0.3 15 6.1 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Tenui_NCP PF04876.7 EME27821.1 - 0.062 12.8 0.1 0.58 9.6 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim PF01751.17 EME27821.1 - 0.071 13.0 0.2 1.9 8.5 0.0 2.2 1 1 1 2 2 2 0 Toprim domain Caleosin PF05042.8 EME27821.1 - 0.089 12.3 0.2 2.3 7.7 0.2 2.7 1 1 0 1 1 1 0 Caleosin related protein RloB PF13707.1 EME27821.1 - 0.45 10.1 5.3 34 4.0 3.6 2.5 1 1 0 1 1 1 0 RloB-like protein Ferritin_2 PF13668.1 EME27822.1 - 3.6e-11 43.1 2.5 5.8e-11 42.4 1.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain Epimerase PF01370.16 EME27823.1 - 7.4e-49 166.3 0.0 1.2e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME27823.1 - 3.4e-16 58.9 0.1 4.6e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EME27823.1 - 5.3e-14 51.5 0.0 7.8e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME27823.1 - 5.5e-12 45.1 0.6 6.3e-07 28.5 0.2 2.7 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME27823.1 - 8.9e-12 44.4 0.0 1.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME27823.1 - 1.2e-05 25.2 0.0 7.9e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EME27823.1 - 0.00054 20.0 0.0 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EME27823.1 - 0.0022 17.6 0.0 0.022 14.4 0.0 2.4 3 0 0 3 3 3 1 KR domain NmrA PF05368.8 EME27823.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family UMP1 PF05348.6 EME27824.1 - 3.6e-16 59.2 0.0 4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Sec3_C PF09763.4 EME27825.1 - 1.2e-07 30.2 6.9 1.2e-07 30.2 4.8 3.7 4 1 1 5 5 5 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EME27825.1 - 2.8e-07 30.2 0.2 6.5e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Transpep_BrtH PF14399.1 EME27825.1 - 0.014 14.6 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Ribosomal_L18e PF00828.14 EME27826.1 - 3.1e-21 76.0 1.0 5.6e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 YscK PF06578.7 EME27826.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Mpp10 PF04006.7 EME27827.1 - 1.6e-66 224.9 59.5 1.9e-62 211.5 14.9 3.0 1 1 2 3 3 3 3 Mpp10 protein RyR PF02026.11 EME27828.1 - 0.066 13.2 0.2 0.093 12.7 0.2 1.3 1 0 0 1 1 1 0 RyR domain APO_RNA-bind PF05634.6 EME27828.1 - 0.07 12.3 1.0 0.079 12.1 0.7 1.1 1 0 0 1 1 1 0 APO RNA-binding MARVEL PF01284.18 EME27829.1 - 0.011 15.5 17.6 0.034 13.9 12.2 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF3112 PF11309.3 EME27829.1 - 0.39 10.5 4.6 8.2 6.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) zf-DHHC PF01529.15 EME27829.1 - 1 8.7 5.0 1.8 7.9 3.3 1.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF997 PF06196.7 EME27829.1 - 2.5 7.6 9.7 4.7 6.8 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF997) SprT-like PF10263.4 EME27830.1 - 1.5e-38 131.9 2.6 2.4e-38 131.2 1.8 1.3 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EME27830.1 - 0.39 10.7 2.7 0.9 9.5 1.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Myb_DNA-binding PF00249.26 EME27831.1 - 7.7e-12 45.0 0.5 2.4e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain FGGY_C PF02782.11 EME27832.1 - 7.5e-20 71.3 0.0 1.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME27832.1 - 1.8e-18 66.8 0.0 9.7e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Bac_globin PF01152.16 EME27832.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial-like globin DUF1764 PF08576.5 EME27833.1 - 0.021 15.5 3.9 0.027 15.2 2.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Otopetrin PF03189.8 EME27833.1 - 0.045 12.7 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Otopetrin TMEM190 PF15431.1 EME27833.1 - 0.07 13.0 0.3 0.095 12.6 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 190 SID-1_RNA_chan PF13965.1 EME27833.1 - 0.074 11.2 0.1 0.072 11.2 0.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NST1 PF13945.1 EME27833.1 - 0.084 12.9 8.4 0.098 12.7 5.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_A3 PF02160.10 EME27833.1 - 0.084 12.4 0.6 0.096 12.2 0.4 1.1 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) OATP PF03137.15 EME27833.1 - 0.15 10.0 0.1 0.18 9.8 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF755 PF05501.6 EME27833.1 - 0.19 11.8 11.5 0.28 11.2 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) YihI PF04220.7 EME27833.1 - 0.23 10.7 7.5 0.3 10.3 5.2 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Sec62 PF03839.11 EME27833.1 - 0.24 10.7 5.3 0.49 9.7 2.5 1.9 1 1 1 2 2 2 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 EME27833.1 - 0.54 10.0 3.0 0.66 9.7 2.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PBP1_TM PF14812.1 EME27833.1 - 4.3 7.7 8.8 3 8.2 4.9 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EMP24_GP25L PF01105.19 EME27834.1 - 6.5e-25 87.9 0.0 9.1e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RPN7 PF10602.4 EME27835.1 - 5.6e-50 169.1 2.4 1.1e-49 168.2 1.7 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EME27835.1 - 1.9e-14 53.8 3.9 5.4e-14 52.3 0.1 3.0 3 1 0 3 3 3 1 PCI domain TPR_12 PF13424.1 EME27835.1 - 0.016 15.1 4.1 0.4 10.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME27835.1 - 0.13 11.9 1.5 20 4.9 0.0 3.2 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 EME27835.1 - 2.1 8.4 10.6 1.1 9.3 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME27835.1 - 7.2 6.4 9.4 1.2 8.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EME27836.1 - 6.4e-38 128.6 2.7 9.8e-28 95.8 0.7 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EME27836.1 - 1.9e-18 66.9 9.3 1.5e-07 31.4 0.1 3.6 2 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME27836.1 - 1.2e-07 31.6 0.4 1.3e-06 28.3 0.2 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME27836.1 - 4.7e-07 29.9 1.7 1.8e-06 28.1 0.5 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME27836.1 - 0.00042 20.3 1.8 0.0041 17.2 0.2 3.3 4 1 1 5 5 5 1 Thioredoxin-like Calsequestrin PF01216.12 EME27836.1 - 0.00065 18.5 1.1 0.018 13.8 0.4 2.7 3 0 0 3 3 3 1 Calsequestrin AhpC-TSA PF00578.16 EME27836.1 - 0.0016 18.1 0.6 0.0048 16.5 0.2 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EME27836.1 - 0.009 15.8 0.1 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain 4HBT PF03061.17 EME27837.1 - 2.9e-10 40.1 0.0 4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Cupin_3 PF05899.7 EME27839.1 - 1.8e-06 27.1 0.0 4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 EME27839.1 - 9.1e-05 22.0 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 EME27839.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EME27840.1 - 1.3e-06 27.6 0.0 2.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 EME27840.1 - 8e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.2 EME27840.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Cupin RNA_pol_Rpb2_6 PF00562.23 EME27841.1 - 2.3e-124 415.0 0.0 4.2e-124 414.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME27841.1 - 4.9e-54 182.3 0.1 7.5e-54 181.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EME27841.1 - 4.3e-29 100.5 0.0 1.3e-28 99.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EME27841.1 - 3e-27 95.2 2.2 5.4e-27 94.4 1.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EME27841.1 - 2.7e-21 75.1 0.1 6.5e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EME27841.1 - 1.3e-19 69.6 0.0 3.1e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EME27841.1 - 5.4e-12 45.4 0.2 1.5e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF1272 PF06906.6 EME27841.1 - 0.052 13.4 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF1751 PF08551.5 EME27842.1 - 1.4e-14 54.2 5.7 2.3e-14 53.4 3.9 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) WD40 PF00400.27 EME27843.1 - 4.3e-09 35.9 0.2 0.00077 19.2 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat SUKH_5 PF14567.1 EME27843.1 - 0.016 14.6 0.0 2.6 7.5 0.0 3.2 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Nup160 PF11715.3 EME27843.1 - 0.026 12.6 0.7 1.7 6.6 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF693 PF05113.8 EME27843.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF693) DIM1 PF02966.11 EME27846.1 - 3.6e-65 217.4 0.1 4.1e-65 217.3 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EME27846.1 - 0.0037 16.9 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Metallophos PF00149.23 EME27847.1 - 1.7e-17 63.4 0.1 2.8e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME27847.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CcmH PF03918.9 EME27847.1 - 0.084 11.8 0.2 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Tetraspannin PF00335.15 EME27848.1 - 1.8e-16 60.1 16.3 2.9e-16 59.4 11.3 1.2 1 0 0 1 1 1 1 Tetraspanin family Abhydrolase_6 PF12697.2 EME27849.1 - 1.2e-39 136.4 0.0 2.5e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME27849.1 - 1.2e-17 63.9 0.0 7.5e-17 61.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME27849.1 - 1.1e-16 61.1 0.0 1.6e-15 57.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Smr PF01713.16 EME27849.1 - 2.2e-09 37.3 0.0 5.6e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Smr domain Peptidase_S9 PF00326.16 EME27849.1 - 1e-06 28.1 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 EME27849.1 - 4.3e-06 25.4 0.0 7.6e-05 21.3 0.0 2.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 EME27849.1 - 8.1e-06 25.5 0.0 0.00045 19.8 0.0 2.4 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EME27849.1 - 4e-05 23.1 0.0 0.0094 15.4 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EME27849.1 - 0.00062 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EME27849.1 - 0.0014 17.9 0.0 0.013 14.7 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1057 PF06342.7 EME27849.1 - 0.0046 15.8 0.0 0.53 9.0 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 EME27849.1 - 0.012 15.1 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.8 EME27849.1 - 0.022 14.2 0.0 0.26 10.6 0.0 2.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EME27849.1 - 0.099 12.2 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EME27849.1 - 0.18 10.6 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme GATase_2 PF00310.16 EME27850.1 - 4.4e-22 78.2 0.2 8e-18 64.2 0.0 2.6 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EME27850.1 - 3.5e-21 75.2 0.0 7.6e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EME27850.1 - 2.7e-20 72.6 0.0 4.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EME27850.1 - 3.7e-14 52.5 0.1 6.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EME27850.1 - 1.3e-08 33.8 0.0 2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 EME27851.1 - 6.2e-22 77.7 0.1 9.6e-18 64.0 0.0 2.6 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EME27851.1 - 4.1e-21 74.9 0.0 9.1e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EME27851.1 - 3.1e-20 72.4 0.0 5.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EME27851.1 - 4.3e-14 52.3 0.1 7.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EME27851.1 - 1.6e-08 33.6 0.0 2.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II YIF1 PF03878.10 EME27852.1 - 2.1e-50 171.1 0.7 3e-50 170.6 0.5 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EME27852.1 - 4.9e-06 26.1 3.2 7.2e-06 25.6 2.2 1.2 1 0 0 1 1 1 1 Yip1 domain Herpes_pp85 PF04637.7 EME27852.1 - 0.02 13.2 1.3 0.027 12.7 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Amino_oxidase PF01593.19 EME27853.1 - 2.1e-71 241.3 0.0 2.5e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME27853.1 - 1.1e-15 57.3 0.1 2.4e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME27853.1 - 6.3e-06 25.3 0.1 0.0019 17.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME27853.1 - 2.6e-05 23.4 0.3 5.5e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME27853.1 - 7.6e-05 21.7 1.5 0.00033 19.6 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EME27853.1 - 9.2e-05 21.6 0.3 0.0002 20.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EME27853.1 - 0.00024 21.0 0.2 0.0007 19.5 0.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME27853.1 - 0.00044 19.4 0.0 0.0031 16.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME27853.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME27853.1 - 0.0033 17.7 0.2 0.041 14.2 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME27853.1 - 0.01 14.7 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EME27853.1 - 0.013 13.9 1.2 0.031 12.7 0.6 1.7 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EME27853.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EME27853.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EME27853.1 - 0.14 10.3 0.0 0.59 8.2 0.0 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like CPSase_L_chain PF00289.17 EME27853.1 - 0.16 12.0 0.2 0.45 10.6 0.0 1.8 2 0 0 2 2 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain zf-CDGSH PF09360.5 EME27854.1 - 3.7e-12 45.8 2.8 1.6e-11 43.8 0.1 2.4 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type GDA1_CD39 PF01150.12 EME27854.1 - 0.0074 14.8 0.0 0.0086 14.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EamA PF00892.15 EME27856.1 - 2.3e-05 24.4 22.4 0.00038 20.4 5.3 3.2 2 1 0 2 2 2 2 EamA-like transporter family TauE PF01925.14 EME27856.1 - 1.8 7.9 15.1 0.074 12.4 2.8 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE bHLH-MYC_N PF14215.1 EME27857.1 - 0.0017 18.6 0.0 0.0041 17.3 0.0 1.7 1 1 1 2 2 2 1 bHLH-MYC and R2R3-MYB transcription factors N-terminal GAF_2 PF13185.1 EME27857.1 - 0.0076 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 GAF domain YqgF PF14639.1 EME27857.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 GAF PF01590.21 EME27857.1 - 0.069 13.2 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 GAF domain HLH PF00010.21 EME27857.1 - 0.18 11.5 0.8 0.34 10.6 0.6 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Voltage_CLC PF00654.15 EME27859.1 - 8.1e-43 146.7 25.9 3.3e-41 141.4 14.7 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel DUF3147 PF11345.3 EME27859.1 - 0.00076 19.4 2.5 1.1 9.3 0.1 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF3147) DUF204 PF02659.10 EME27859.1 - 7.5 6.7 12.2 1.5 8.9 1.5 4.3 4 0 0 4 4 4 0 Domain of unknown function DUF MFS_1 PF07690.11 EME27860.1 - 2.2e-22 79.2 35.0 2.2e-22 79.2 24.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_6 PF08030.7 EME27861.1 - 8.9e-15 54.9 0.3 4.1e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME27861.1 - 1.2e-14 54.4 13.9 3.1e-14 53.1 9.7 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME27861.1 - 0.00013 21.8 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EME27861.1 - 0.032 14.8 0.0 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain NIR_SIR PF01077.17 EME27862.1 - 7.5e-39 132.6 0.0 2.1e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EME27862.1 - 1.3e-32 111.2 0.0 7.9e-16 57.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Oxidored_molyb PF00174.14 EME27863.1 - 2.9e-29 101.6 0.0 5.2e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain PXB PF12828.2 EME27865.1 - 0.13 11.8 0.4 17 4.9 0.1 2.8 2 1 0 3 3 3 0 PX-associated Arch_ATPase PF01637.13 EME27867.1 - 0.00048 19.9 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase Glyoxalase PF00903.20 EME27868.1 - 5.3e-23 81.3 0.3 1.1e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME27868.1 - 1.4e-16 60.4 0.2 5.6e-08 32.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME27868.1 - 1.2e-10 41.9 0.0 0.00014 22.4 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EME27868.1 - 5.3e-06 26.4 0.1 1.8e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EME27868.1 - 6.9e-05 22.8 0.0 1.2 9.0 0.0 4.1 3 1 0 3 3 3 2 Glyoxalase-like domain NblA PF04485.7 EME27870.1 - 5.5e-13 48.5 0.3 9.3e-13 47.8 0.2 1.3 1 0 0 1 1 1 1 Phycobilisome degradation protein nblA DUF3513 PF12026.3 EME27872.1 - 0.83 9.1 5.7 0.31 10.5 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3513) MAS20 PF02064.10 EME27872.1 - 1.8 8.4 9.8 0.43 10.5 3.3 2.4 2 1 1 3 3 3 0 MAS20 protein import receptor DAHP_synth_2 PF01474.11 EME27873.1 - 1.8e-180 600.0 0.0 2.1e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Asp PF00026.18 EME27874.1 - 2.6e-49 168.1 12.4 3.4e-49 167.8 8.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME27874.1 - 7.8e-16 58.0 0.1 2.6e-15 56.3 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EME27874.1 - 9.9e-06 25.9 0.7 0.034 14.6 0.0 3.2 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 EME27874.1 - 0.0015 18.3 0.0 0.088 12.6 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EME27874.1 - 0.0097 15.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease PAP2 PF01569.16 EME27875.1 - 0.27 10.8 13.9 3.4 7.3 9.6 2.4 1 1 0 1 1 1 0 PAP2 superfamily DUF457 PF04307.9 EME27875.1 - 0.66 9.2 14.4 0.7 9.2 1.2 3.4 3 0 0 3 3 3 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) ABC_tran PF00005.22 EME27877.1 - 1.2e-37 129.2 0.0 2.8e-37 128.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME27877.1 - 9e-21 74.4 14.3 1.2e-20 74.1 9.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EME27877.1 - 4.1e-07 29.4 1.5 1.2e-05 24.6 1.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME27877.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EME27877.1 - 0.00051 20.1 0.1 0.29 11.0 0.0 2.8 2 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EME27877.1 - 0.00051 20.1 0.2 0.0038 17.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME27877.1 - 0.0022 17.4 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EME27877.1 - 0.0024 17.3 0.1 0.0081 15.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 EME27877.1 - 0.017 13.8 0.0 0.029 13.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 EME27877.1 - 0.021 14.0 0.0 0.049 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME27877.1 - 0.034 14.0 0.1 0.28 11.1 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EME27877.1 - 0.039 13.5 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EME27877.1 - 0.044 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EME27877.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EME27877.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain BAR PF03114.13 EME27878.1 - 2.1e-07 30.6 3.6 3.3e-07 30.0 2.5 1.3 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EME27878.1 - 0.0014 18.0 6.0 0.0092 15.3 4.2 2.1 1 1 0 1 1 1 1 Arfaptin-like domain DUF745 PF05335.8 EME27878.1 - 0.023 14.1 0.4 0.023 14.1 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF2663 PF10864.3 EME27878.1 - 0.03 14.5 0.2 0.076 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Cor1 PF04803.7 EME27878.1 - 0.032 14.0 8.8 0.38 10.5 0.1 3.6 2 1 1 3 3 3 0 Cor1/Xlr/Xmr conserved region V-SNARE PF05008.10 EME27878.1 - 0.042 14.0 0.6 0.042 14.0 0.4 3.2 2 1 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Corona_S2 PF01601.11 EME27878.1 - 0.14 10.2 0.9 3.8 5.4 0.0 2.0 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein DUF632 PF04782.7 EME27878.1 - 0.15 11.1 7.2 0.33 10.0 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF632) Mod_r PF07200.8 EME27878.1 - 0.33 10.8 9.1 13 5.6 4.2 3.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PTPlike_phytase PF14566.1 EME27878.1 - 0.36 10.8 3.5 0.68 9.9 2.2 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Laminin_II PF06009.7 EME27878.1 - 0.45 10.2 3.0 0.66 9.7 0.1 2.3 2 1 0 2 2 2 0 Laminin Domain II DUF1090 PF06476.7 EME27878.1 - 2.7 7.6 8.5 3.5 7.3 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) 6PF2K PF01591.13 EME27879.1 - 1.1e-77 260.0 0.1 1.4e-77 259.6 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EME27879.1 - 9.4e-31 107.0 0.2 2.2e-30 105.8 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EME27879.1 - 2.5e-06 27.4 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME27879.1 - 0.00056 20.7 0.1 0.0018 19.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME27879.1 - 0.016 14.3 0.0 0.065 12.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 EME27879.1 - 0.051 12.7 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EME27879.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase SNARE PF05739.14 EME27880.1 - 1.9e-18 65.9 2.4 1.9e-18 65.9 1.7 3.9 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EME27880.1 - 9.2e-13 48.2 9.4 9.2e-13 48.2 6.5 2.4 2 0 0 2 2 2 1 Syntaxin DUF2242 PF10001.4 EME27880.1 - 0.016 15.0 2.6 0.31 10.8 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) HrpB7 PF09486.5 EME27880.1 - 0.58 10.0 7.8 6.2 6.7 0.6 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 EME27880.1 - 0.75 10.2 12.4 0.13 12.7 1.8 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Nsp1_C PF05064.8 EME27880.1 - 5.9 6.5 18.4 0.14 11.8 3.9 3.0 2 1 1 3 3 3 0 Nsp1-like C-terminal region SNARE PF05739.14 EME27881.1 - 1.7e-18 66.0 2.4 1.7e-18 66.0 1.7 4.3 5 0 0 5 5 5 1 SNARE domain Syntaxin PF00804.20 EME27881.1 - 8.4e-13 48.3 9.4 8.4e-13 48.3 6.5 2.6 3 0 0 3 3 3 1 Syntaxin Corona_S2 PF01601.11 EME27881.1 - 0.03 12.4 6.5 0.26 9.3 0.6 2.2 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein HrpB7 PF09486.5 EME27881.1 - 0.54 10.1 7.8 5.7 6.8 0.6 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Syntaxin-6_N PF09177.6 EME27881.1 - 1.9 8.9 14.2 0.13 12.6 1.7 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Syntaxin-18_N PF10496.4 EME27881.1 - 2 8.2 10.8 0.17 11.7 0.2 3.2 4 0 0 4 4 4 0 SNARE-complex protein Syntaxin-18 N-terminus Nsp1_C PF05064.8 EME27881.1 - 8.1 6.1 19.2 0.16 11.5 4.1 3.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region tRNA-synt_1b PF00579.20 EME27882.1 - 1.9e-20 73.1 0.0 3.9e-20 72.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HA2 PF04408.18 EME27883.1 - 2.3e-29 101.3 0.1 8.1e-29 99.6 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EME27883.1 - 3.2e-21 75.3 0.0 7.7e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EME27883.1 - 5.3e-10 39.0 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME27883.1 - 2.1e-06 27.8 0.2 7.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EME27883.1 - 2.8e-06 26.9 0.1 5.7e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.18 EME27883.1 - 6.8e-06 26.0 0.6 0.0014 18.6 0.2 2.7 2 0 0 2 2 2 1 S1 RNA binding domain T2SE PF00437.15 EME27883.1 - 0.00093 18.1 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EME27883.1 - 0.0012 18.9 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EME27883.1 - 0.026 14.2 0.1 0.066 12.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EME27883.1 - 0.052 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EME27883.1 - 0.091 12.6 0.2 0.67 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EME27883.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EME27883.1 - 0.12 12.6 1.3 0.35 11.1 0.0 2.5 3 0 0 3 3 2 0 ABC transporter NT5C PF06941.7 EME27884.1 - 1.8e-37 128.7 0.3 2.1e-37 128.4 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.2 EME27884.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HMG_box PF00505.14 EME27885.1 - 5.6e-10 39.3 0.9 8.2e-10 38.8 0.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EME27885.1 - 8.1e-09 35.7 0.9 1.2e-08 35.1 0.6 1.2 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EME27885.1 - 3.4e-06 27.2 2.9 4e-06 27.0 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) YABBY PF04690.8 EME27885.1 - 0.00043 20.5 0.1 0.00045 20.5 0.1 1.2 1 0 0 1 1 1 1 YABBY protein IRF-3 PF10401.4 EME27885.1 - 0.031 13.8 0.4 0.035 13.6 0.3 1.0 1 0 0 1 1 1 0 Interferon-regulatory factor 3 CHDNT PF08073.7 EME27885.1 - 0.13 11.9 1.1 0.22 11.2 0.8 1.4 1 1 0 1 1 1 0 CHDNT (NUC034) domain Pkinase PF00069.20 EME27887.1 - 5.5e-52 176.4 0.0 1.5e-51 175.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.24 EME27887.1 - 3.6e-41 140.4 0.0 2.2e-39 134.6 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME27887.1 - 2.7e-28 97.6 0.0 6.5e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase_Tyr PF07714.12 EME27887.1 - 2e-23 82.7 0.0 3.5e-22 78.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RWD PF05773.17 EME27887.1 - 1.1e-13 51.0 0.0 3.5e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 EME27887.1 - 5e-11 42.2 0.2 5.1e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 EME27887.1 - 0.003 16.5 0.0 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like SecA_DEAD PF07517.9 EME27887.1 - 0.025 13.8 0.0 0.096 11.9 0.0 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain Helicase_C_2 PF13307.1 EME27887.1 - 0.041 13.8 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain zf-CCHC PF00098.18 EME27887.1 - 0.21 11.5 2.2 0.41 10.6 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Homoserine_dh PF00742.14 EME27888.1 - 4.3e-55 186.1 0.0 8.7e-55 185.1 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.23 EME27888.1 - 9.5e-41 139.9 0.0 1.9e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.11 EME27888.1 - 1e-20 74.2 0.0 2.6e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.1 EME27888.1 - 2e-18 65.6 1.3 2.3e-08 33.4 0.2 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EME27888.1 - 1.9e-16 59.1 0.1 1e-07 31.3 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.1 EME27888.1 - 0.059 13.0 0.5 15 5.3 0.0 2.9 3 0 0 3 3 3 0 ACT domain R3H PF01424.17 EME27889.1 - 1.1e-05 25.0 0.1 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EME27889.1 - 0.00045 20.0 13.4 0.00045 20.0 9.3 13.8 15 0 0 15 15 15 6 NF-X1 type zinc finger zf-RING_2 PF13639.1 EME27890.1 - 1.6e-14 53.4 4.9 2.7e-14 52.6 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME27890.1 - 2.6e-09 36.5 2.5 4.8e-09 35.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27890.1 - 1.5e-08 34.1 1.8 2.4e-08 33.4 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME27890.1 - 2.1e-08 34.1 6.8 9.3e-08 32.0 4.0 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME27890.1 - 2.5e-08 33.7 4.1 4.4e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27890.1 - 1.3e-06 28.0 2.5 2.3e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME27890.1 - 0.0049 16.6 3.6 0.04 13.7 2.9 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EME27890.1 - 0.012 15.4 3.7 0.035 13.9 2.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME27890.1 - 0.037 13.7 2.7 0.094 12.4 1.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EME27890.1 - 0.046 13.5 1.7 0.091 12.5 1.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.2 EME27890.1 - 0.052 13.5 3.4 0.11 12.5 2.3 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EME27890.1 - 0.081 12.5 1.5 0.17 11.4 1.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EME27890.1 - 0.53 10.2 3.7 2.4 8.1 2.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EME27890.1 - 0.6 9.8 2.6 1.4 8.6 1.8 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.1 EME27890.1 - 0.97 9.0 4.3 2.6 7.6 3.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 CHCH PF06747.8 EME27892.1 - 0.00018 21.2 5.2 0.00031 20.5 3.6 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EME27892.1 - 0.00039 20.3 1.3 0.0006 19.8 0.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF1903 PF08991.5 EME27892.1 - 0.0083 16.2 1.9 0.015 15.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) ADH_N PF08240.7 EME27893.1 - 2.3e-31 107.7 0.1 2.3e-31 107.7 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME27893.1 - 5.6e-28 97.0 2.0 8.4e-28 96.5 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME27893.1 - 1.3e-05 26.1 0.6 2.6e-05 25.1 0.4 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME27893.1 - 0.0025 17.4 0.4 0.005 16.4 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EME27893.1 - 0.0043 16.2 0.1 0.0089 15.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_transf_25 PF01755.12 EME27894.1 - 1.2e-11 44.6 0.0 2.9e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4132 PF13569.1 EME27894.1 - 0.0098 15.4 1.3 0.025 14.1 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4132) Acyl-CoA_dh_1 PF00441.19 EME27895.1 - 4.5e-30 104.7 0.4 7.6e-30 103.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME27895.1 - 7.2e-26 90.9 0.0 1.6e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME27895.1 - 9.9e-19 66.6 0.0 2.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME27895.1 - 1.4e-07 31.8 0.1 2.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PerC PF06069.6 EME27895.1 - 0.11 12.5 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 PerC transcriptional activator LON PF02190.11 EME27896.1 - 1.2e-21 77.4 0.3 1.6e-21 76.9 0.2 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EME27897.1 - 0.00024 20.6 12.5 0.00058 19.4 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EME27897.1 - 0.0013 18.4 6.9 0.0013 18.4 4.8 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EME27897.1 - 0.003 17.5 15.1 0.0079 16.1 10.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27897.1 - 0.003 17.2 16.5 0.0082 15.8 11.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME27897.1 - 0.0039 16.8 7.4 0.011 15.3 5.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EME27897.1 - 0.0053 16.5 14.8 0.013 15.2 10.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME27897.1 - 0.0053 16.3 15.1 0.015 14.9 10.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME27897.1 - 0.09 12.3 9.3 0.23 11.0 6.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Viral_protease PF08715.5 EME27897.1 - 0.14 11.1 1.3 0.22 10.5 0.9 1.2 1 0 0 1 1 1 0 Papain like viral protease zf-RING_4 PF14570.1 EME27897.1 - 0.2 11.2 11.9 0.2 11.2 3.9 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4193 PF13834.1 EME27897.1 - 3.4 7.8 6.7 1.3 9.2 2.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4193) zf-C3HC4_4 PF15227.1 EME27897.1 - 4.2 7.3 15.5 22 5.0 10.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING HypA PF01155.14 EME27897.1 - 9.6 5.9 10.0 1.8e+02 1.8 6.9 2.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FAD_syn PF06574.7 EME27898.1 - 3.3e-13 49.5 0.0 7.7e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 FAD synthetase DUF1771 PF08590.5 EME27900.1 - 8.1e-16 57.8 7.9 1.3e-15 57.0 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.24 EME27900.1 - 2e-13 49.7 0.1 3.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 KH domain Smr PF01713.16 EME27900.1 - 2.8e-12 46.6 1.1 6.3e-12 45.5 0.7 1.6 1 0 0 1 1 1 1 Smr domain KH_3 PF13014.1 EME27900.1 - 1e-10 40.9 0.2 2.9e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 KH domain Ribosomal_S30AE PF02482.14 EME27900.1 - 0.033 14.6 1.8 3.1 8.3 0.0 2.9 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein ATP-synt_B PF00430.13 EME27900.1 - 0.15 11.8 6.2 0.25 11.1 4.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3633 PF12315.3 EME27902.1 - 0.017 14.4 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) SR-25 PF10500.4 EME27902.1 - 0.14 11.6 8.2 0.21 11.0 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EME27903.1 - 2.9e-61 206.9 0.0 4.9e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27903.1 - 4.5e-32 111.1 0.0 8e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME27903.1 - 9.1e-07 28.1 0.0 2.1e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 Kinase-like DUF547 PF04784.9 EME27903.1 - 5.5e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Seadorna_VP7 PF07387.6 EME27903.1 - 0.037 12.8 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EME27903.1 - 0.052 13.2 0.0 0.2 11.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EME27903.1 - 0.065 12.5 0.1 1 8.6 0.0 2.7 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EME27904.1 - 3e-61 206.8 0.0 5.1e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME27904.1 - 4.6e-32 111.0 0.0 8.2e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME27904.1 - 9.5e-07 28.0 0.0 2.2e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like DUF547 PF04784.9 EME27904.1 - 5.5e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Seadorna_VP7 PF07387.6 EME27904.1 - 0.041 12.7 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EME27904.1 - 0.058 13.1 0.0 0.2 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EME27904.1 - 0.069 12.4 0.1 1 8.6 0.0 2.7 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Det1 PF09737.4 EME27905.1 - 5.3e-65 219.7 0.2 1.2e-64 218.6 0.1 1.5 1 1 0 1 1 1 1 De-etiolated protein 1 Det1 BSD PF03909.12 EME27906.1 - 2.5e-12 46.3 0.3 5.2e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 BSD domain Stk19 PF10494.4 EME27908.1 - 2.1e-27 96.1 0.0 3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 NolX PF05819.6 EME27908.1 - 0.054 11.8 0.1 1.5 7.1 0.0 2.0 2 0 0 2 2 2 0 NolX protein DUF4046 PF13255.1 EME27908.1 - 0.1 11.3 0.1 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) Mito_carr PF00153.22 EME27909.1 - 2e-66 219.7 1.0 2.2e-26 91.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4257 PF14074.1 EME27909.1 - 0.032 13.8 0.1 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Hydrolase_like2 PF13246.1 EME27909.1 - 0.13 12.1 0.1 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Ank_2 PF12796.2 EME27910.1 - 8.1e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME27910.1 - 1.1e-13 50.1 0.1 1.2e-08 34.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EME27910.1 - 3.2e-13 49.8 0.1 6.8e-07 29.6 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME27910.1 - 2.2e-12 46.7 0.1 6.3e-10 38.9 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME27910.1 - 2.8e-08 33.2 0.0 0.00011 22.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat DUF2508 PF10704.4 EME27911.1 - 0.24 11.5 1.7 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) UFC1 PF08694.6 EME27912.1 - 3e-76 254.3 0.0 3.6e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EME27912.1 - 0.039 13.8 0.8 0.33 10.8 0.8 1.9 1 1 1 2 2 2 0 RWD domain UQ_con PF00179.21 EME27912.1 - 0.04 13.3 0.4 0.062 12.7 0.2 1.5 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Pex2_Pex12 PF04757.9 EME27913.1 - 5.8e-45 153.4 5.4 7.8e-45 153.0 3.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EME27913.1 - 2.3e-07 30.7 6.1 5e-07 29.6 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME27913.1 - 0.00095 18.7 4.1 0.0016 18.0 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME27913.1 - 0.0018 18.0 6.1 0.0037 17.0 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EME27913.1 - 0.0092 15.7 1.4 0.021 14.5 1.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ALO PF04030.9 EME27913.1 - 0.016 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase zf-rbx1 PF12678.2 EME27913.1 - 0.11 12.6 1.1 0.2 11.7 0.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EME27913.1 - 0.31 10.9 6.9 0.61 10.0 4.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EME27913.1 - 0.69 9.6 4.5 1.6 8.4 3.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME27913.1 - 1.2 8.8 5.2 2.5 7.8 3.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TauE PF01925.14 EME27914.1 - 4.2e-12 46.0 11.0 4.2e-12 46.0 7.7 1.7 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE PHO4 PF01384.15 EME27914.1 - 0.16 10.5 7.4 0.11 11.1 3.2 1.9 1 1 1 2 2 2 0 Phosphate transporter family RHD3 PF05879.7 EME27915.1 - 4.8e-71 239.7 0.5 6.2e-71 239.3 0.3 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EME27915.1 - 0.0017 18.3 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EME27915.1 - 0.023 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Septin Miro PF08477.8 EME27915.1 - 0.027 14.9 0.0 0.32 11.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 EME27915.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF2340 PF10209.4 EME27915.1 - 0.11 12.6 0.2 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) DUF4224 PF13986.1 EME27915.1 - 0.25 10.9 1.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Arch_ATPase PF01637.13 EME27916.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DEAD PF00270.24 EME27917.1 - 3.8e-35 120.8 0.1 8.6e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME27917.1 - 5.4e-18 64.6 0.2 1.3e-09 37.8 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EME27917.1 - 2.5e-08 33.9 0.3 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME27917.1 - 0.1 12.7 0.1 0.56 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EME27918.1 - 6.5e-42 142.8 0.0 1.3e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME27918.1 - 6.7e-22 77.1 0.0 2.6e-21 75.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EME27918.1 - 6.5e-14 51.2 0.0 1.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EME27918.1 - 0.0027 17.5 2.6 0.0033 17.2 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PRP1_N PF06424.7 EME27918.1 - 0.16 12.2 9.8 0.51 10.6 6.8 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal adh_short PF00106.20 EME27919.1 - 7.5e-30 104.0 0.1 1e-29 103.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME27919.1 - 2.2e-14 53.8 0.0 2.9e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME27919.1 - 5.9e-11 42.3 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME27919.1 - 1.2e-08 35.2 0.1 3.1e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME27919.1 - 4.8e-05 22.9 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME27919.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EME27919.1 - 0.043 12.9 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EME27919.1 - 0.047 13.4 0.4 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_2 PF03446.10 EME27919.1 - 0.083 12.7 0.1 0.96 9.2 0.0 2.3 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mito_carr PF00153.22 EME27920.1 - 1.5e-55 184.8 1.3 7.2e-24 83.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA_33 PF13671.1 EME27920.1 - 0.1 12.4 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF1049 PF06305.6 EME27920.1 - 0.1 12.0 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1325 PF07039.6 EME27921.1 - 1.5e-24 86.0 0.3 4.3e-24 84.5 0.2 1.8 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 EME27921.1 - 8.2e-05 22.3 0.1 0.0002 21.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) SNARE PF05739.14 EME27922.1 - 1.1e-09 37.8 12.0 6.9e-08 32.0 3.2 2.6 2 1 0 2 2 2 2 SNARE domain V-SNARE_C PF12352.3 EME27922.1 - 1.2e-07 31.6 3.3 4.3e-06 26.6 0.2 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 EME27922.1 - 0.0096 16.1 1.5 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EME27922.1 - 2.3 8.0 6.6 10 5.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HARE-HTH PF05066.8 EME27923.1 - 5.7e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain DUF2180 PF09947.4 EME27923.1 - 0.00016 21.3 3.5 0.00045 19.9 2.4 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) zf-HC5HC2H_2 PF13832.1 EME27923.1 - 0.02 14.8 0.5 0.02 14.8 0.3 2.5 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME27923.1 - 4.1 7.6 12.3 83 3.4 7.9 2.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain TMCO5 PF14992.1 EME27924.1 - 0.00068 18.8 6.7 0.0014 17.7 4.6 1.5 1 0 0 1 1 1 1 TMCO5 family GAS PF13851.1 EME27924.1 - 0.0017 17.6 12.2 0.043 13.0 1.3 2.7 3 0 0 3 3 3 2 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 EME27924.1 - 0.0025 17.4 0.7 0.0025 17.4 0.5 2.6 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 Tropomyosin_1 PF12718.2 EME27924.1 - 0.0038 17.0 14.6 0.028 14.2 2.4 3.9 3 1 0 3 3 3 1 Tropomyosin like SlyX PF04102.7 EME27924.1 - 0.005 17.1 4.0 11 6.4 0.0 4.4 3 1 1 4 4 4 0 SlyX WEMBL PF05701.6 EME27924.1 - 0.016 13.7 7.6 0.03 12.8 5.3 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_I PF06008.9 EME27924.1 - 0.016 14.5 1.5 0.016 14.5 1.1 3.1 3 1 0 4 4 3 0 Laminin Domain I TBPIP PF07106.8 EME27924.1 - 0.031 13.8 9.1 0.029 13.9 0.9 2.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 EME27924.1 - 0.032 13.9 0.9 0.032 13.9 0.7 3.7 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EME27924.1 - 0.037 13.6 19.5 0.018 14.6 8.2 3.2 2 1 1 3 3 2 0 IncA protein SLX9 PF15341.1 EME27924.1 - 0.047 14.1 11.6 0.052 13.9 0.0 3.0 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 CCDC144C PF14915.1 EME27924.1 - 0.049 12.5 12.3 0.24 10.2 8.5 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF972 PF06156.8 EME27924.1 - 0.072 13.4 12.8 1.2 9.5 0.9 3.3 2 1 1 3 3 2 0 Protein of unknown function (DUF972) Cast PF10174.4 EME27924.1 - 0.075 11.0 14.5 0.67 7.9 10.1 2.2 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Fez1 PF06818.10 EME27924.1 - 0.11 12.5 9.1 0.46 10.4 6.3 2.0 1 1 0 1 1 1 0 Fez1 bZIP_1 PF00170.16 EME27924.1 - 0.14 12.1 19.7 0.65 9.9 0.5 3.6 3 0 0 3 3 3 0 bZIP transcription factor CorA PF01544.13 EME27924.1 - 0.23 10.4 8.6 0.063 12.3 0.8 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Kinetocho_Slk19 PF12709.2 EME27924.1 - 0.31 11.1 6.7 2.3 8.3 0.9 2.8 2 1 0 2 2 2 0 Central kinetochore-associated Viral_P18 PF04521.8 EME27924.1 - 0.35 10.2 6.8 0.18 11.2 0.6 2.7 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Phage_GP20 PF06810.6 EME27924.1 - 0.47 9.8 8.2 3.7 6.9 1.0 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.6 EME27924.1 - 0.48 9.0 11.7 0.058 12.0 0.6 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein EzrA PF06160.7 EME27924.1 - 0.53 8.3 11.9 1.1 7.3 1.0 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Rootletin PF15035.1 EME27924.1 - 0.66 9.9 15.7 0.41 10.6 5.4 2.7 2 1 1 3 3 2 0 Ciliary rootlet component, centrosome cohesion FliJ PF02050.11 EME27924.1 - 0.75 9.8 13.4 2.5 8.1 1.0 3.0 3 0 0 3 3 2 0 Flagellar FliJ protein DUF724 PF05266.9 EME27924.1 - 0.87 9.1 8.8 0.058 13.0 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 EME27924.1 - 0.88 8.5 11.8 0.28 10.1 5.6 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EME27924.1 - 1.2 8.7 9.1 2.1 7.9 4.9 2.3 1 1 1 2 2 2 0 Mnd1 family LURAP PF14854.1 EME27924.1 - 1.3 8.7 18.0 2 8.1 0.1 4.2 4 0 0 4 4 4 0 Leucine rich adaptor protein DUF4164 PF13747.1 EME27924.1 - 1.3 9.1 10.6 7.8 6.7 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 EME27924.1 - 1.5 8.6 9.3 2.5 7.9 0.3 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 EME27924.1 - 1.9 8.5 10.3 8.3 6.4 6.3 2.5 1 1 1 2 2 2 0 DivIVA protein Prefoldin PF02996.12 EME27924.1 - 2 8.0 7.0 0.7 9.5 0.8 3.0 2 1 2 4 4 4 0 Prefoldin subunit ADIP PF11559.3 EME27924.1 - 2.3 8.1 17.5 0.045 13.6 1.4 3.5 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding THOC7 PF05615.8 EME27924.1 - 2.6 8.3 14.5 2.2 8.5 1.1 3.5 3 1 1 4 4 3 0 Tho complex subunit 7 TMF_DNA_bd PF12329.3 EME27924.1 - 3.8 7.3 18.0 3.7 7.4 1.4 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EME27924.1 - 4.5 7.0 22.4 0.14 11.9 2.5 3.7 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 EME27924.1 - 5.5 6.8 14.5 0.89 9.3 2.6 3.6 2 2 0 3 3 3 0 Prefoldin subunit DUF4094 PF13334.1 EME27924.1 - 6 7.3 11.7 5.2 7.5 0.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Laminin_II PF06009.7 EME27924.1 - 7.7 6.2 15.6 0.39 10.4 0.6 3.9 2 2 1 3 3 3 0 Laminin Domain II Med9 PF07544.8 EME27924.1 - 7.8 6.3 11.3 4.2 7.1 1.4 3.3 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Kinesin-relat_1 PF12711.2 EME27924.1 - 9.3 6.7 11.6 2 8.8 1.2 3.2 3 0 0 3 3 2 0 Kinesin motor Methyltransf_11 PF08241.7 EME27925.1 - 2.1e-18 66.5 0.0 3.2e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME27925.1 - 1.1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME27925.1 - 1.4e-09 37.7 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME27925.1 - 1.8e-08 33.8 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME27925.1 - 4.3e-08 33.5 0.0 8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME27925.1 - 5.5e-07 29.6 0.0 8.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME27925.1 - 4.1e-06 27.0 0.0 7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EME27925.1 - 0.00017 21.3 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EME27925.1 - 0.00017 22.1 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EME27925.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 EME27925.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EME27925.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EME27925.1 - 0.02 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EME27925.1 - 0.048 12.8 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF938 PF06080.7 EME27925.1 - 0.12 11.8 0.0 0.57 9.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Sec61_beta PF03911.11 EME27926.1 - 1.5e-14 53.4 0.4 2e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Aa_trans PF01490.13 EME27927.1 - 1.3e-55 188.5 35.3 1.5e-55 188.3 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EME27927.1 - 1.2e-10 40.5 29.8 1.2e-10 40.5 20.7 2.2 1 1 1 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 EME27927.1 - 6.5e-08 31.7 12.4 6.5e-08 31.7 8.6 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EME27927.1 - 5.2e-05 22.0 23.0 5.2e-05 22.0 16.0 2.6 1 1 0 2 2 2 1 Spore germination protein Aminotran_3 PF00202.16 EME27928.1 - 5.1e-84 282.0 0.0 6.2e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III zf-CCCH PF00642.19 EME27930.1 - 3.7e-15 55.1 11.2 3.1e-08 33.0 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME27930.1 - 4.4e-06 26.4 11.3 0.0037 17.2 1.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type WD40 PF00400.27 EME27931.1 - 5.5e-38 127.5 35.3 1.2e-07 31.3 0.3 12.0 12 1 0 12 12 12 9 WD domain, G-beta repeat WD40 PF00400.27 EME27932.1 - 3.5e-38 128.1 37.1 3.5e-08 33.0 0.8 11.8 12 0 0 12 12 12 9 WD domain, G-beta repeat Myb_DNA-binding PF00249.26 EME27933.1 - 3.2e-27 94.2 2.4 1.6e-10 40.8 0.3 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME27933.1 - 2.3e-17 62.8 14.6 2.6e-08 33.8 0.1 4.7 5 0 0 5 5 5 3 Myb-like DNA-binding domain Pro_dh PF01619.13 EME27934.1 - 1.9e-57 194.6 1.0 6.5e-57 192.8 0.8 1.7 2 0 0 2 2 2 1 Proline dehydrogenase DnaJ_CXXCXGXG PF00684.14 EME27935.1 - 0.13 12.3 8.4 2.1 8.4 6.0 2.7 1 1 1 2 2 2 0 DnaJ central domain DUF2162 PF09930.4 EME27935.1 - 0.89 8.6 3.7 5.5 6.0 0.5 2.2 2 0 0 2 2 2 0 Predicted transporter (DUF2162) Ribosomal_L13 PF00572.13 EME27936.1 - 3.2e-43 146.8 0.1 1.4e-42 144.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L13 Sigma70_r1_1 PF03979.9 EME27936.1 - 0.12 12.3 0.4 1.8 8.5 0.1 2.5 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 Ribosomal_L13 PF00572.13 EME27937.1 - 4.3e-43 146.4 0.0 7.1e-43 145.7 0.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L13 TauE PF01925.14 EME27938.1 - 2.4e-35 122.1 22.6 3.5e-35 121.6 15.7 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE JmjC PF02373.17 EME27939.1 - 2e-29 102.1 0.3 6.2e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EME27939.1 - 1.6e-11 43.5 0.3 1.6e-11 43.5 0.2 2.3 3 0 0 3 3 3 1 jmjN domain ARID PF01388.16 EME27939.1 - 2.3e-09 36.9 0.3 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EME27939.1 - 5.9e-07 29.4 0.9 2e-06 27.7 0.6 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger ArsA_ATPase PF02374.10 EME27939.1 - 0.11 11.4 0.3 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase JAB PF01398.16 EME27940.1 - 4.6e-13 48.9 0.0 8.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EME27940.1 - 2e-11 43.9 0.6 2.9e-11 43.4 0.4 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Aa_trans PF01490.13 EME27941.1 - 1e-70 238.2 2.8 1.4e-70 237.8 1.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPC12 PF06645.8 EME27941.1 - 0.24 11.2 1.0 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SOBP PF15279.1 EME27941.1 - 1.1 9.5 5.5 7.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein AAA PF00004.24 EME27942.1 - 1.7e-09 37.9 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME27942.1 - 1.6e-08 34.7 0.1 5.7e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME27942.1 - 4.7e-06 26.7 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EME27942.1 - 0.002 17.1 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EME27942.1 - 0.0041 16.8 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain TSCPD PF12637.2 EME27942.1 - 0.017 15.0 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 TSCPD domain NACHT PF05729.7 EME27942.1 - 0.034 13.7 0.0 0.079 12.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DUF2577 PF10844.3 EME27942.1 - 0.045 13.7 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Myb_DNA-bind_6 PF13921.1 EME27943.1 - 1.3e-07 31.6 14.2 0.06 13.4 0.0 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME27943.1 - 1.9e-06 27.8 0.1 0.16 12.0 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain HI0933_like PF03486.9 EME27943.1 - 0.13 10.6 1.1 0.23 9.8 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Myb_DNA-bind_6 PF13921.1 EME27944.1 - 1e-07 31.9 13.9 0.059 13.4 0.0 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME27944.1 - 1.7e-06 27.9 0.1 0.16 12.0 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain HI0933_like PF03486.9 EME27944.1 - 0.13 10.7 1.1 0.22 9.9 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.19 EME27946.1 - 2.9e-90 303.0 31.7 3.4e-90 302.7 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME27946.1 - 1.2e-22 80.1 25.6 1.2e-22 80.1 17.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1435 PF07256.7 EME27946.1 - 1.8 8.5 6.0 7.6 6.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Glyco_hydro_31 PF01055.21 EME27948.1 - 1.3e-82 277.9 7.6 2.9e-82 276.8 5.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 SHMT PF00464.14 EME27949.1 - 3.9e-200 664.3 0.0 4.6e-200 664.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EME27949.1 - 0.00096 18.1 0.0 0.004 16.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME27949.1 - 0.0057 15.8 0.0 0.012 14.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase V-ATPase_G PF03179.10 EME27949.1 - 0.082 13.2 0.3 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Fer2 PF00111.22 EME27950.1 - 7.7e-13 48.0 0.1 1.1e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mo25 PF08569.6 EME27951.1 - 1.3e-99 333.4 6.6 1.3e-99 333.4 4.6 1.8 1 1 0 2 2 2 1 Mo25-like HEAT_2 PF13646.1 EME27951.1 - 0.023 14.9 0.1 0.58 10.4 0.0 2.7 2 1 0 2 2 2 0 HEAT repeats Arm PF00514.18 EME27951.1 - 0.027 14.2 0.1 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat BAG PF02179.11 EME27951.1 - 0.43 10.7 3.2 12 6.1 0.0 3.4 3 0 0 3 3 3 0 BAG domain Peptidase_C50 PF03568.12 EME27952.1 - 9.3e-59 199.0 4.4 9.3e-59 199.0 3.1 2.5 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.2 EME27952.1 - 0.0016 17.6 0.0 0.006 15.7 0.0 2.0 1 1 0 1 1 1 1 CHAT domain UIM PF02809.15 EME27952.1 - 0.027 14.0 1.7 0.12 11.9 1.1 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif MMS1_N PF10433.4 EME27955.1 - 4.3e-66 223.0 0.0 7.2e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EME27955.1 - 5.1e-56 190.0 0.0 8.1e-55 186.1 0.0 2.5 2 1 0 2 2 2 1 CPSF A subunit region Fe_hyd_lg_C PF02906.9 EME27956.1 - 7e-43 146.9 0.0 8.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain CLASP_N PF12348.3 EME27958.1 - 2.4e-27 95.7 2.0 9.4e-26 90.5 0.9 3.4 3 1 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 EME27958.1 - 7.1e-11 42.2 2.0 0.13 12.6 0.0 5.3 4 1 0 4 4 4 4 HEAT repeats HEAT PF02985.17 EME27958.1 - 2.7e-09 36.3 11.5 0.0065 16.4 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EME27958.1 - 0.14 12.6 6.6 12 6.5 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat ParA PF10609.4 EME27959.1 - 2.8e-30 104.0 0.1 1.1e-29 102.0 0.1 2.1 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EME27959.1 - 5.4e-20 71.6 0.0 8.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF971 PF06155.7 EME27959.1 - 4e-17 62.4 0.1 8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF59 PF01883.14 EME27959.1 - 8.2e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_31 PF13614.1 EME27959.1 - 9.9e-10 38.5 0.0 3e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EME27959.1 - 8.8e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EME27959.1 - 0.0045 16.0 3.0 0.058 12.4 0.9 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EME27959.1 - 0.014 14.5 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EME27959.1 - 0.014 14.7 0.3 0.073 12.4 0.1 1.9 2 0 0 2 2 2 0 YhjQ protein VirC1 PF07015.6 EME27959.1 - 0.035 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein Glycos_trans_3N PF02885.12 EME27962.1 - 0.00023 20.6 0.9 0.00036 20.0 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain zf-A20 PF01754.11 EME27962.1 - 0.16 11.6 0.3 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 A20-like zinc finger Coatomer_WDAD PF04053.9 EME27963.1 - 1.3e-104 350.5 0.0 2.4e-104 349.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EME27963.1 - 3.4e-68 230.1 2.3 5.1e-68 229.5 1.6 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EME27963.1 - 6.9e-56 184.2 6.9 1.7e-10 40.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EME27963.1 - 0.00097 17.3 4.1 0.12 10.4 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 TPR_2 PF07719.12 EME27963.1 - 0.011 15.5 3.8 4 7.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Nucleoporin_N PF08801.6 EME27963.1 - 0.013 14.2 1.5 7.5 5.1 0.6 3.7 2 1 0 3 3 3 0 Nup133 N terminal like PPR PF01535.15 EME27963.1 - 0.027 14.4 0.0 7.4 6.7 0.0 3.7 3 0 0 3 3 3 0 PPR repeat NAD_Gly3P_dh_N PF01210.18 EME27964.1 - 6.6e-50 168.9 0.1 7.6e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EME27964.1 - 0.00043 20.6 1.7 0.0036 17.6 0.3 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 EME27964.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Semialdhyde_dh PF01118.19 EME27964.1 - 0.086 13.1 0.1 0.38 11.0 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA_2 PF07724.9 EME27965.1 - 1.2e-43 149.0 0.3 1.4e-34 119.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EME27965.1 - 1.3e-13 51.2 0.1 1.8e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EME27965.1 - 3.3e-07 30.0 1.2 1.5e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EME27965.1 - 5.2e-07 29.4 0.2 2.5e-05 24.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME27965.1 - 5.3e-06 27.2 0.0 1.3e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME27965.1 - 7.9e-06 25.9 0.1 3.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME27965.1 - 1.6e-05 25.0 0.1 0.0008 19.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EME27965.1 - 0.00016 20.9 0.4 0.0024 17.0 0.2 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME27965.1 - 0.00021 21.6 0.0 0.00055 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EME27965.1 - 0.00056 18.7 1.5 0.0014 17.4 1.0 1.6 1 1 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EME27965.1 - 0.00057 19.0 0.3 0.0056 15.7 0.1 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME27965.1 - 0.0031 17.4 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EME27965.1 - 0.0032 16.9 0.0 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EME27965.1 - 0.0034 16.5 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EME27965.1 - 0.0085 15.9 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME27965.1 - 0.012 15.0 0.1 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EME27965.1 - 0.014 15.3 0.1 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME27965.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EME27965.1 - 0.027 14.1 2.1 0.24 11.0 0.1 2.4 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 EME27965.1 - 0.037 13.4 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 EME27965.1 - 0.044 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EME27965.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DEAD PF00270.24 EME27965.1 - 0.061 12.8 0.2 0.19 11.2 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.7 EME27965.1 - 0.084 12.5 0.3 3.5 7.2 0.0 2.9 3 1 0 3 3 2 0 NACHT domain DsrD PF08679.6 EME27965.1 - 1.2 9.2 4.4 2.3 8.2 0.9 2.9 2 1 1 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) FliG_C PF01706.11 EME27966.1 - 0.0027 17.6 1.4 0.0042 17.0 0.1 2.0 2 0 0 2 2 2 1 FliG C-terminal domain RNA_pol_A_CTD PF03118.10 EME27966.1 - 0.0046 16.3 1.5 0.022 14.1 0.4 2.4 2 0 0 2 2 2 1 Bacterial RNA polymerase, alpha chain C terminal domain SSB PF00436.20 EME27967.1 - 3.5e-17 62.1 0.1 5.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family DUF3533 PF12051.3 EME27968.1 - 0.094 11.4 0.9 0.14 10.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HATPase_c_3 PF13589.1 EME27969.1 - 8.1e-13 48.2 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EME27969.1 - 6e-12 45.0 0.0 1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EME27969.1 - 2.6e-11 43.3 0.2 2.3e-10 40.2 0.1 2.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EME27969.1 - 2.4e-09 36.8 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME27970.1 - 8.4e-13 48.1 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EME27970.1 - 6.2e-12 45.0 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EME27970.1 - 2.5e-09 36.8 0.0 4.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EME27970.1 - 1.5e-06 27.9 0.4 0.067 12.7 0.1 3.3 2 1 0 2 2 2 2 MutL C terminal dimerisation domain Peptidase_M41 PF01434.13 EME27972.1 - 3.8e-74 248.7 4.2 6.4e-74 248.0 2.9 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME27972.1 - 8.4e-43 145.7 0.0 2.8e-42 144.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME27972.1 - 4.3e-06 26.4 0.0 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EME27972.1 - 3e-05 23.1 0.2 0.00013 21.0 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EME27972.1 - 5.3e-05 22.1 0.0 9.4e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EME27972.1 - 7.6e-05 22.7 0.1 0.0022 18.0 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EME27972.1 - 0.0002 22.1 0.0 0.00068 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME27972.1 - 0.00047 19.8 0.2 0.0019 17.9 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EME27972.1 - 0.00085 18.7 0.2 0.0022 17.4 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EME27972.1 - 0.0025 16.9 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EME27972.1 - 0.0026 17.9 0.8 0.037 14.1 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EME27972.1 - 0.0038 17.1 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME27972.1 - 0.0045 16.3 0.5 0.03 13.7 0.3 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EME27972.1 - 0.0099 15.8 0.7 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EME27972.1 - 0.013 14.6 0.2 0.029 13.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EME27972.1 - 0.014 15.2 0.0 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EME27972.1 - 0.017 14.9 0.0 0.065 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EME27972.1 - 0.029 14.6 0.2 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME27972.1 - 0.045 13.2 0.4 0.52 9.7 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EME27972.1 - 0.1 12.2 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EME27972.1 - 0.15 11.2 0.2 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EME27972.1 - 0.32 11.2 2.1 0.55 10.5 0.3 2.1 2 0 0 2 2 2 0 ABC transporter ParcG PF10274.4 EME27973.1 - 0.091 12.6 0.7 0.45 10.4 0.2 1.9 1 1 1 2 2 2 0 Parkin co-regulated protein Phage_GP20 PF06810.6 EME27973.1 - 1.5 8.2 5.6 0.39 10.1 0.3 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Seipin PF06775.9 EME27974.1 - 1.4e-17 63.9 0.6 1.7e-17 63.5 0.4 1.0 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF35 PF01796.12 EME27974.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 DUF35 OB-fold domain DUF912 PF06024.7 EME27974.1 - 1.9 8.5 4.0 3.4 7.7 2.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YajC PF02699.10 EME27974.1 - 2.6 7.7 4.0 4.8 6.9 2.8 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Seipin PF06775.9 EME27975.1 - 4.2e-21 75.3 0.0 4.9e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Pyrophosphatase PF00719.14 EME27976.1 - 3.3e-48 163.0 0.1 5.5e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase FBPase PF00316.15 EME27976.1 - 2.9e-46 157.7 0.0 6.5e-45 153.3 0.0 2.1 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase Ost4 PF10215.4 EME27976.1 - 2.3 7.7 5.0 8.1 6.0 1.7 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase Adeno_E3 PF06040.6 EME27977.1 - 0.029 14.3 0.5 0.059 13.3 0.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein RNB PF00773.14 EME27978.1 - 5.4e-100 334.8 2.4 5.4e-100 334.8 1.7 2.1 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EME27978.1 - 9.5e-14 51.6 2.1 9.5e-14 51.6 1.4 2.4 2 0 0 2 2 2 1 PIN domain NYN_YacP PF05991.6 EME27978.1 - 0.00026 20.7 0.6 0.0021 17.8 0.1 2.5 2 0 0 2 2 2 1 YacP-like NYN domain DUF3598 PF12204.3 EME27980.1 - 0.0047 16.2 0.0 0.069 12.3 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3598) COPI_C PF06957.6 EME27981.1 - 3.1e-28 98.4 3.1 3.2e-28 98.4 2.2 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus IcmL PF11393.3 EME27981.1 - 0.025 14.4 0.1 0.05 13.5 0.0 1.5 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein NAD_Gly3P_dh_C PF07479.9 EME27982.1 - 8.7e-48 161.8 0.1 1.3e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EME27982.1 - 2.5e-41 141.0 0.1 4.6e-41 140.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_C PF03720.10 EME27982.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Acyltransferase PF01553.16 EME27983.1 - 1.1e-25 89.6 0.0 4.4e-23 81.1 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 EME27984.1 - 1.6e-29 102.0 0.0 2.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1350 PF07082.6 EME27985.1 - 2.2e-43 148.1 0.3 4.3e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) Abhydrolase_6 PF12697.2 EME27985.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME27985.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Myb_DNA-binding PF00249.26 EME27986.1 - 2.8e-10 40.0 0.0 9.6e-10 38.3 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME27986.1 - 3.7e-06 26.9 0.9 2.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain GST_N PF02798.15 EME27987.1 - 8.6e-15 54.6 0.1 2.9e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME27987.1 - 8.4e-08 32.0 0.1 2.9e-07 30.3 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME27987.1 - 1.2e-05 25.4 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME27987.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME27987.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA PF00004.24 EME27988.1 - 2e-33 115.3 0.0 5.2e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME27988.1 - 2.8e-09 37.8 0.0 1.2e-08 35.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME27988.1 - 2.8e-06 27.6 0.1 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME27988.1 - 3.6e-06 26.9 0.0 7.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME27988.1 - 5.7e-06 25.5 0.0 0.00069 18.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EME27988.1 - 7.3e-05 22.5 0.1 0.00045 19.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME27988.1 - 0.00031 20.8 0.1 0.0041 17.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME27988.1 - 0.00046 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME27988.1 - 0.0012 18.5 0.3 0.0036 17.0 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EME27988.1 - 0.0019 18.2 0.1 0.043 13.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EME27988.1 - 0.0042 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME27988.1 - 0.0069 16.3 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EME27988.1 - 0.034 13.2 0.0 5.1 6.1 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 EME27988.1 - 0.055 12.8 0.0 4.6 6.5 0.1 2.7 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EME27988.1 - 0.056 12.5 0.1 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MltA PF03562.12 EME27988.1 - 0.059 13.0 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 MltA specific insert domain Zeta_toxin PF06414.7 EME27988.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 EME27988.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.1 EME27988.1 - 0.12 12.1 0.0 0.48 10.2 0.0 2.0 1 0 0 1 1 1 0 Prefoldin subunit Sigma54_activ_2 PF14532.1 EME27988.1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain BRK PF07533.11 EME27989.1 - 2.8e-05 23.4 0.0 5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 BRK domain bZIP_1 PF00170.16 EME27990.1 - 1.1e-05 25.3 11.5 2.2e-05 24.3 8.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor PcfJ PF14284.1 EME27990.1 - 0.059 12.8 3.3 0.088 12.3 2.3 1.3 1 0 0 1 1 1 0 PcfJ-like protein bZIP_1 PF00170.16 EME27991.1 - 1.1e-05 25.3 11.5 2.2e-05 24.3 8.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor PcfJ PF14284.1 EME27991.1 - 0.059 12.8 3.3 0.088 12.3 2.3 1.3 1 0 0 1 1 1 0 PcfJ-like protein Gemin7 PF11095.3 EME27992.1 - 5.7e-16 58.0 0.0 6.6e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Sm_multidrug_ex PF06695.6 EME27993.1 - 3.8e-29 101.3 3.8 1.6e-28 99.2 2.6 2.1 1 1 0 1 1 1 1 Putative small multi-drug export protein DUF4131 PF13567.1 EME27993.1 - 6.3 6.1 7.2 0.45 9.9 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sm_multidrug_ex PF06695.6 EME27994.1 - 3.8e-29 101.3 3.8 1.6e-28 99.2 2.6 2.1 1 1 0 1 1 1 1 Putative small multi-drug export protein DUF4131 PF13567.1 EME27994.1 - 6.3 6.1 7.2 0.45 9.9 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tyrosinase PF00264.15 EME27995.1 - 2.9e-36 125.7 0.1 4e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase GST_N PF02798.15 EME27996.1 - 2.3e-16 59.6 0.0 4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME27996.1 - 3.9e-12 46.0 0.3 5.7e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME27996.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME27996.1 - 3.8e-05 23.5 0.0 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME27996.1 - 8.2e-05 23.0 0.1 0.00017 21.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME27996.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Herpes_MCP PF03122.9 EME27996.1 - 0.04 11.2 0.0 0.051 10.9 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein DUF3461 PF11944.3 EME27996.1 - 0.099 12.4 2.2 0.24 11.2 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) RWP-RK PF02042.10 EME27997.1 - 7.1e-23 80.1 0.5 1.2e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF3585 PF12130.3 EME27997.1 - 0.078 12.8 7.3 0.12 12.2 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) Med9 PF07544.8 EME27997.1 - 0.19 11.4 4.0 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF972 PF06156.8 EME27997.1 - 0.26 11.6 8.5 1.4 9.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 EME27997.1 - 0.79 9.4 4.8 4.1 7.1 0.4 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 EME27997.1 - 0.82 9.5 8.3 1.4 8.8 0.3 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF2802 PF10975.3 EME27997.1 - 0.83 9.4 4.4 4.2 7.1 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DEAD PF00270.24 EME27998.1 - 2.8e-43 147.3 0.0 4.2e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME27998.1 - 4.2e-25 87.4 0.1 9.6e-25 86.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME27998.1 - 0.0044 16.8 0.0 0.064 13.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EME27998.1 - 0.096 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3458 PF11940.3 EME27999.1 - 1.5e-121 405.7 0.1 3.7e-121 404.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EME27999.1 - 5.6e-60 203.4 0.2 9e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EME27999.1 - 9.1e-17 61.2 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2268 PF10026.4 EME27999.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Vma12 PF11712.3 EME28000.1 - 0.0017 18.1 3.7 0.0017 18.1 2.6 2.2 1 1 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PsbN PF02468.10 EME28000.1 - 0.028 14.0 0.7 0.028 14.0 0.5 2.2 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) Herpes_US9 PF06072.6 EME28000.1 - 0.068 13.0 0.1 0.068 13.0 0.1 2.7 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 NfeD PF01957.13 EME28000.1 - 0.11 12.5 0.2 0.11 12.5 0.1 2.3 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2721 PF11026.3 EME28000.1 - 0.14 11.7 1.6 0.63 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 5TM-5TMR_LYT PF07694.7 EME28000.1 - 0.37 10.1 8.5 0.15 11.3 3.4 1.9 1 1 1 2 2 2 0 5TMR of 5TMR-LYT DUF3112 PF11309.3 EME28000.1 - 2.2 8.0 9.5 0.3 10.8 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF4231 PF14015.1 EME28000.1 - 2.7 8.0 5.4 5.8 6.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Tetraspannin PF00335.15 EME28000.1 - 2.9 7.1 13.7 4.2 6.5 3.1 2.3 1 1 1 2 2 2 0 Tetraspanin family DUF3816 PF12822.2 EME28000.1 - 5.5 6.8 14.6 1.3e+02 2.3 10.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Abi PF02517.11 EME28000.1 - 8.9 6.5 11.6 2.3 8.4 0.4 2.5 1 1 1 2 2 2 0 CAAX protease self-immunity NAD_binding_10 PF13460.1 EME28001.1 - 2.1e-06 27.8 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME28001.1 - 0.058 12.8 0.0 0.45 9.8 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRN3 PF05327.6 EME28002.1 - 1e-38 132.8 12.4 1.5e-20 72.8 1.3 2.3 2 1 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 DUF592 PF04574.8 EME28002.1 - 0.064 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) LpxK PF02606.9 EME28003.1 - 3.2e-37 128.2 0.8 6.7e-36 123.8 0.5 2.3 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase DUF1890 PF09001.6 EME28003.1 - 0.17 11.8 0.1 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) LpxK PF02606.9 EME28004.1 - 2.7e-40 138.3 0.1 4.4e-39 134.3 0.1 2.2 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase tRNA-synt_2 PF00152.15 EME28005.1 - 4.5e-92 308.3 0.2 7.1e-92 307.7 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME28005.1 - 9.1e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME28005.1 - 8.1e-08 31.7 0.4 0.0024 17.1 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EME28005.1 - 0.00035 20.2 0.2 0.04 13.4 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Flu_B_NS1 PF02942.9 EME28005.1 - 0.022 13.7 0.4 0.037 12.9 0.3 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) U79_P34 PF03064.11 EME28005.1 - 0.22 11.0 4.0 0.32 10.4 2.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 EME28005.1 - 0.87 8.2 6.9 1.5 7.5 4.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Thioredoxin PF00085.15 EME28006.1 - 3.6e-29 100.4 0.2 9.7e-29 99.1 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.15 EME28006.1 - 1.1e-14 54.2 0.0 3.8e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EME28006.1 - 2.7e-09 36.5 0.0 2.7e-09 36.5 0.0 2.2 3 0 0 3 3 2 1 UBA/TS-N domain Thioredoxin_8 PF13905.1 EME28006.1 - 3.3e-06 27.1 0.1 1.3e-05 25.2 0.1 2.0 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EME28006.1 - 0.0016 18.0 0.1 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EME28006.1 - 0.0042 17.2 0.1 0.0042 17.2 0.1 2.6 2 2 0 2 2 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME28006.1 - 0.029 14.3 0.1 0.029 14.3 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like TraF PF13728.1 EME28006.1 - 0.03 13.8 0.0 0.03 13.8 0.0 3.1 2 1 1 3 3 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 EME28006.1 - 0.067 12.7 0.0 0.067 12.7 0.0 3.0 2 1 0 2 2 1 0 Thioredoxin CAF-1_p150 PF11600.3 EME28006.1 - 0.32 10.3 36.0 0.52 9.6 25.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.4 EME28006.1 - 0.36 9.7 18.1 0.6 9.0 12.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF572 PF04502.8 EME28006.1 - 1.5 7.9 22.6 2.4 7.2 15.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ycf1 PF05758.7 EME28006.1 - 2.1 5.9 12.0 2.7 5.6 8.3 1.1 1 0 0 1 1 1 0 Ycf1 V_ATPase_I PF01496.14 EME28006.1 - 8.5 4.0 8.5 11 3.7 5.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HECT PF00632.20 EME28007.1 - 1.2e-100 336.7 0.0 2.3e-100 335.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SBP_bac_11 PF13531.1 EME28007.1 - 0.3 10.6 0.0 0.48 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein CCT PF06203.9 EME28008.1 - 1.8e-08 33.8 12.8 3.6e-08 32.9 8.8 1.5 1 0 0 1 1 1 1 CCT motif DUF482 PF04339.7 EME28009.1 - 2e-118 395.4 0.4 2.3e-118 395.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF482 Acetyltransf_6 PF13480.1 EME28009.1 - 1.6e-09 37.8 0.1 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YycH PF07435.6 EME28009.1 - 0.024 13.3 0.1 0.035 12.8 0.1 1.2 1 0 0 1 1 1 0 YycH protein SopA PF13981.1 EME28009.1 - 0.056 13.4 0.2 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 SopA-like central domain E2F_TDP PF02319.15 EME28009.1 - 0.12 11.9 3.0 0.38 10.3 0.6 2.4 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Nol1_Nop2_Fmu PF01189.12 EME28010.1 - 2.3e-25 89.5 0.0 2.9e-24 85.9 0.0 2.1 2 0 0 2 2 2 1 NOL1/NOP2/sun family FA_desaturase PF00487.19 EME28010.1 - 1.8e-23 83.3 0.4 3.2e-23 82.4 0.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Tim44 PF04280.10 EME28010.1 - 1.1e-12 48.2 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Methyltransf_31 PF13847.1 EME28010.1 - 4.6e-05 23.0 0.0 0.00011 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME28010.1 - 0.00023 21.2 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EME28010.1 - 0.0019 18.1 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28010.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EME28010.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME28010.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PUA PF01472.15 EME28010.1 - 0.2 11.4 0.0 0.48 10.1 0.0 1.6 2 0 0 2 2 2 0 PUA domain Nol1_Nop2_Fmu PF01189.12 EME28011.1 - 2e-25 89.7 0.0 2.7e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 NOL1/NOP2/sun family FA_desaturase PF00487.19 EME28011.1 - 1.8e-23 83.3 0.4 3e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Tim44 PF04280.10 EME28011.1 - 9.9e-13 48.3 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain Methyltransf_31 PF13847.1 EME28011.1 - 4.2e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME28011.1 - 0.00021 21.3 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EME28011.1 - 0.0018 18.2 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28011.1 - 0.01 16.3 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EME28011.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PUA PF01472.15 EME28011.1 - 0.19 11.5 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 PUA domain G_glu_transpept PF01019.16 EME28012.1 - 7.1e-129 430.5 0.0 8e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Methyltransf_23 PF13489.1 EME28013.1 - 3.4e-11 43.1 0.1 4.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28013.1 - 2.2e-06 27.3 0.5 0.00014 21.4 0.1 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28013.1 - 5.5e-05 23.4 0.2 0.00011 22.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28013.1 - 0.00015 22.1 0.1 0.00027 21.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28013.1 - 0.00058 20.4 0.1 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28013.1 - 0.014 15.8 0.1 0.037 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF2562 PF10814.3 EME28013.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Methyltransf_26 PF13659.1 EME28013.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S4 PF00163.14 EME28014.1 - 1.4e-10 41.4 3.8 1.4e-10 41.4 2.6 1.8 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EME28014.1 - 9.8e-10 37.7 0.0 1.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain DASH_Dad3 PF08656.5 EME28014.1 - 0.072 12.7 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad3 Occludin_ELL PF07303.8 EME28014.1 - 0.17 12.6 0.3 0.17 12.6 0.2 2.5 2 1 1 3 3 3 0 Occludin homology domain DEAD PF00270.24 EME28015.1 - 3.9e-45 153.3 0.1 9.6e-45 152.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28015.1 - 2.5e-21 75.3 0.0 5e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EME28015.1 - 2e-18 65.6 3.2 3.7e-18 64.8 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EME28015.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME28015.1 - 0.00017 21.7 0.5 0.017 15.2 0.4 2.9 2 1 0 2 2 2 1 AAA domain SspH PF08141.7 EME28015.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DUF1253 PF06862.7 EME28015.1 - 0.026 12.9 0.8 0.35 9.2 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) zf-RING_2 PF13639.1 EME28016.1 - 1.2e-10 40.9 1.0 2.2e-10 40.2 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME28016.1 - 5.2e-06 26.3 0.5 7.9e-06 25.8 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME28016.1 - 6.3e-06 26.2 0.2 1.2e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME28016.1 - 2.4e-05 23.8 0.3 4e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28016.1 - 0.00052 19.6 0.4 0.00079 19.1 0.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME28016.1 - 0.0021 17.8 0.6 0.004 16.9 0.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EME28016.1 - 0.021 14.8 0.8 0.059 13.3 0.3 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EME28016.1 - 0.021 14.5 0.4 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME28016.1 - 0.027 14.1 0.9 0.083 12.6 0.3 1.9 2 0 0 2 2 2 0 RING-type zinc-finger DUF4335 PF14233.1 EME28016.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Prok-RING_1 PF14446.1 EME28016.1 - 0.1 12.3 0.5 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EME28017.1 - 1.3e-15 56.8 7.0 2.3e-15 56.1 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME28017.1 - 2.1e-10 40.5 2.5 4e-10 39.6 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME28017.1 - 2.5e-08 33.8 5.7 3.8e-08 33.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME28017.1 - 1.9e-07 30.6 5.4 3e-07 29.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME28017.1 - 3.2e-07 29.9 3.9 4.7e-07 29.3 2.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28017.1 - 7.1e-06 25.6 5.8 1e-05 25.1 4.0 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME28017.1 - 7.1e-05 22.5 4.5 0.00014 21.6 3.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EME28017.1 - 0.013 14.9 3.0 0.19 11.1 0.2 2.8 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EME28017.1 - 0.02 14.5 3.5 0.034 13.8 0.4 2.6 2 1 1 3 3 3 0 RING-type zinc-finger DUF4335 PF14233.1 EME28017.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Prok-RING_1 PF14446.1 EME28017.1 - 0.14 11.8 4.4 0.38 10.5 0.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EME28017.1 - 0.53 10.3 5.1 1.6 8.8 3.5 1.9 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.1 EME28017.1 - 0.54 9.8 6.5 1.5 8.4 4.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EME28017.1 - 0.81 9.6 7.0 3.6 7.6 3.9 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EME28017.1 - 1.1 8.9 3.8 2.1 7.9 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EME28017.1 - 2 8.3 6.1 6.4 6.7 0.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING MCD PF05292.6 EME28018.1 - 1.2e-22 80.1 0.0 1.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) FolB PF02152.13 EME28018.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 Dihydroneopterin aldolase PEP_mutase PF13714.1 EME28021.1 - 2.5e-56 190.5 0.0 2.9e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EME28021.1 - 4.9e-17 61.3 0.3 1.1e-16 60.1 0.2 1.5 1 1 1 2 2 2 1 Isocitrate lyase family Mito_carr PF00153.22 EME28022.1 - 1.5e-76 252.1 7.5 5.1e-27 93.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 EME28023.1 - 2.1e-22 79.8 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME28023.1 - 7.2e-11 42.0 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME28023.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME28023.1 - 6.8e-07 28.9 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME28023.1 - 8.9e-07 29.0 0.0 9e-06 25.8 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding Yippee-Mis18 PF03226.9 EME28025.1 - 5.7e-19 67.9 3.2 6.6e-19 67.7 2.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ecl1 PF12855.2 EME28025.1 - 0.35 10.1 5.1 4.2 6.7 1.2 2.3 2 0 0 2 2 2 0 Life-span regulatory factor Aldolase PF01081.14 EME28026.1 - 1.5e-39 135.2 0.1 1.7e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase RNB PF00773.14 EME28028.1 - 4.5e-60 203.6 0.0 6.8e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain RWP-RK PF02042.10 EME28029.1 - 2.6e-24 84.7 0.4 5e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF2317 PF10079.4 EME28029.1 - 0.063 11.8 0.1 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) FMN_red PF03358.10 EME28030.1 - 2.6e-14 53.0 0.0 3.5e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EME28030.1 - 1.5e-08 34.7 0.1 3.7e-08 33.4 0.1 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EME28030.1 - 7.2e-08 32.1 0.0 9.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EME28030.1 - 0.062 12.6 0.0 0.27 10.5 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin Sugar_tr PF00083.19 EME28031.1 - 1.2e-70 238.4 23.0 1.4e-70 238.1 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28031.1 - 9.8e-23 80.4 36.7 2.5e-22 79.0 24.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2857 PF11198.3 EME28032.1 - 0.04 13.4 0.2 0.23 10.9 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2857) Med9 PF07544.8 EME28032.1 - 0.046 13.4 0.3 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-RING_2 PF13639.1 EME28033.1 - 6.3e-06 25.9 7.1 6.3e-06 25.9 5.0 3.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME28033.1 - 0.0013 18.3 5.0 0.0013 18.3 3.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EME28033.1 - 0.0035 17.2 7.2 0.0035 17.2 5.0 1.9 2 0 0 2 2 2 1 FANCL C-terminal domain C1_1 PF00130.17 EME28033.1 - 0.0077 15.9 3.0 0.0077 15.9 2.1 3.3 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EME28033.1 - 0.024 14.3 7.6 0.024 14.3 5.3 3.1 3 0 0 3 3 3 0 zinc-RING finger domain SWIM PF04434.12 EME28033.1 - 0.052 13.0 1.4 0.12 11.8 1.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger zf-ribbon_3 PF13248.1 EME28033.1 - 0.47 9.7 0.0 0.47 9.7 0.0 3.8 5 0 0 5 5 5 0 zinc-ribbon domain HIF-1 PF11413.3 EME28034.1 - 0.33 10.1 2.4 0.31 10.2 0.3 1.9 2 0 0 2 2 2 0 Hypoxia-inducible factor-1 DUF674 PF05056.7 EME28037.1 - 0.015 13.9 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) CBF PF03914.12 EME28038.1 - 1.9e-23 82.7 0.1 1.9e-23 82.7 0.1 2.8 4 0 0 4 4 4 1 CBF/Mak21 family CobT PF06213.7 EME28038.1 - 0.9 8.6 17.5 1.7 7.7 12.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EME28038.1 - 7.2 4.3 32.7 11 3.7 0.1 2.1 2 0 0 2 2 2 0 Nop14-like family EF-hand_4 PF12763.2 EME28039.1 - 4.4e-16 58.5 0.0 8.4e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EME28039.1 - 4.7e-05 23.4 0.1 0.18 12.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME28039.1 - 9.3e-05 21.4 0.2 0.033 13.5 0.0 3.3 3 0 0 3 3 3 1 EF hand Laminin_I PF06008.9 EME28039.1 - 0.00019 20.8 2.2 0.00019 20.8 1.5 1.6 2 0 0 2 2 1 1 Laminin Domain I HAUS6_N PF14661.1 EME28039.1 - 0.00042 19.7 1.7 0.001 18.5 1.2 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Filament PF00038.16 EME28039.1 - 0.0017 17.9 6.3 0.0029 17.1 4.3 1.3 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.4 EME28039.1 - 0.0017 17.3 1.5 0.0028 16.6 1.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EME28039.1 - 0.0022 16.7 3.9 0.0038 15.9 2.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein TBPIP PF07106.8 EME28039.1 - 0.0026 17.3 5.9 0.0071 15.9 4.1 1.6 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RasGAP_C PF03836.10 EME28039.1 - 0.0034 17.0 2.1 0.0034 17.0 1.4 2.3 2 1 1 3 3 3 1 RasGAP C-terminus GAS PF13851.1 EME28039.1 - 0.0061 15.7 4.3 0.0061 15.7 3.0 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.10 EME28039.1 - 0.015 15.0 3.7 0.035 13.9 2.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Myosin_tail_1 PF01576.14 EME28039.1 - 0.016 12.9 8.6 0.017 12.9 3.6 1.9 2 0 0 2 2 2 0 Myosin tail Phage_GP20 PF06810.6 EME28039.1 - 0.031 13.7 6.0 0.075 12.4 4.2 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4140 PF13600.1 EME28039.1 - 0.039 14.3 1.9 0.092 13.2 1.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EF-hand_6 PF13405.1 EME28039.1 - 0.061 13.2 0.6 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Reo_sigmaC PF04582.7 EME28039.1 - 0.11 11.6 0.3 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Snapin_Pallidin PF14712.1 EME28039.1 - 0.18 12.1 5.0 0.31 11.3 2.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Cob_adeno_trans PF01923.13 EME28039.1 - 0.2 11.4 2.3 0.13 12.0 0.3 1.6 2 0 0 2 2 1 0 Cobalamin adenosyltransferase DUF724 PF05266.9 EME28039.1 - 0.22 11.1 6.0 0.054 13.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 EME28039.1 - 0.28 10.7 9.6 0.018 14.6 2.9 1.7 2 0 0 2 2 2 0 IncA protein DUF4407 PF14362.1 EME28039.1 - 0.29 10.0 1.9 0.56 9.1 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EME28039.1 - 0.39 8.5 3.3 0.57 7.9 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EME28039.1 - 0.49 9.9 4.4 1.4 8.4 3.1 1.8 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 EME28039.1 - 0.53 9.2 8.7 0.051 12.6 2.7 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF641 PF04859.7 EME28039.1 - 0.83 9.4 7.7 0.11 12.3 1.9 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 EME28039.1 - 2.5 7.9 13.9 0.17 11.8 5.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 EME28039.1 - 3.1 6.9 10.8 0.034 13.4 2.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EME28039.1 - 4.3 5.6 7.5 0.16 10.3 1.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Porphobil_deam PF01379.15 EME28040.1 - 5e-77 257.6 0.0 6.7e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EME28040.1 - 1.2e-16 60.5 0.0 2.1e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SBP_bac_3 PF00497.15 EME28040.1 - 0.013 14.7 0.0 2.5 7.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 UBX PF00789.15 EME28040.1 - 0.086 12.9 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 UBX domain MFS_1 PF07690.11 EME28041.1 - 1e-25 90.2 35.5 1e-25 90.2 24.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME28041.1 - 3.2e-15 55.6 13.5 3.2e-15 55.6 9.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EME28041.1 - 2.4e-09 35.7 7.4 0.00071 17.7 0.0 3.5 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Macro PF01661.16 EME28042.1 - 1.5e-39 134.5 0.1 2.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Macro domain Vps39_2 PF10367.4 EME28043.1 - 0.014 15.5 0.1 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Brix PF04427.13 EME28044.1 - 8.3e-34 116.9 0.2 1.4e-33 116.2 0.1 1.3 1 0 0 1 1 1 1 Brix domain Nyv1_N PF09426.5 EME28044.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Ribosomal_L35Ae PF01247.13 EME28045.1 - 2.1e-40 136.3 2.0 2.4e-40 136.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EME28045.1 - 0.056 13.3 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Ribosomal_L35Ae PF01247.13 EME28046.1 - 2.1e-40 136.3 2.0 2.4e-40 136.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EME28046.1 - 0.056 13.3 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Peptidase_S24 PF00717.18 EME28047.1 - 3.1e-07 29.9 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EME28047.1 - 2.9e-05 23.6 0.0 0.00018 21.0 0.0 1.9 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 LCM PF04072.9 EME28048.1 - 1e-25 90.3 0.1 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Stathmin PF00836.14 EME28048.1 - 0.11 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Stathmin family LCM PF04072.9 EME28049.1 - 1e-25 90.3 0.1 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Stathmin PF00836.14 EME28049.1 - 0.11 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Stathmin family TFIIS_M PF07500.9 EME28050.1 - 1.6e-22 79.6 4.6 5.1e-22 78.1 3.2 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EME28050.1 - 2.6e-07 31.1 0.0 6.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SPOC domain Glucosamine_iso PF01182.15 EME28051.1 - 1.9e-55 187.6 0.0 2.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pentapeptide PF00805.17 EME28052.1 - 8.3e-24 82.3 7.0 5.4e-11 41.4 1.3 3.8 2 1 0 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EME28052.1 - 1.1e-18 66.7 1.2 1.1e-09 37.8 0.1 2.6 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EME28052.1 - 9.1e-12 44.6 1.2 0.00035 20.4 0.0 3.6 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Yippee-Mis18 PF03226.9 EME28053.1 - 8.7e-21 73.7 0.7 1.4e-20 73.1 0.5 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Yippee-Mis18 PF03226.9 EME28054.1 - 1.1e-20 73.4 0.7 1.1e-20 73.4 0.5 1.6 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glycos_transf_3 PF00591.16 EME28055.1 - 1.7e-88 296.2 0.0 2.2e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EME28055.1 - 1.8e-15 56.2 0.2 3.9e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Lipase_GDSL PF00657.17 EME28056.1 - 6.5e-28 98.1 0.0 8.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EME28056.1 - 2.6e-23 83.0 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-CCHC PF00098.18 EME28057.1 - 4.3 7.4 13.3 0.22 11.5 2.3 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-MYND PF01753.13 EME28057.1 - 4.7 7.1 15.8 0.37 10.7 0.2 3.3 3 0 0 3 3 3 0 MYND finger Transp_Tc5_C PF04236.10 EME28057.1 - 9.6 6.5 11.5 0.76 10.0 0.5 2.9 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Pkinase PF00069.20 EME28059.1 - 2.1e-43 148.3 0.0 3.5e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EME28059.1 - 3.5e-24 85.0 0.5 8.5e-24 83.8 0.3 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EME28059.1 - 1.7e-20 73.2 0.0 2.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase S1 PF00575.18 EME28060.1 - 1.4e-30 105.1 1.1 6.6e-13 48.5 0.0 6.9 6 0 0 6 6 6 4 S1 RNA binding domain Suf PF05843.9 EME28060.1 - 1.1e-05 25.3 11.8 5.1e-05 23.1 1.4 3.3 1 1 2 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EME28060.1 - 0.00082 19.6 0.0 0.34 11.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME28060.1 - 0.0011 19.3 0.0 5.1 8.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME28060.1 - 0.0073 15.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.1 EME28060.1 - 0.078 13.4 1.0 63 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cullin PF00888.17 EME28061.1 - 6.3e-39 133.9 5.4 1.1e-38 133.1 0.5 2.7 2 1 0 2 2 2 1 Cullin family BPL_LplA_LipB PF03099.14 EME28061.1 - 1.6e-13 50.7 0.5 1.2e-12 47.8 0.4 2.3 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family APC2 PF08672.6 EME28061.1 - 9.6e-13 48.1 0.3 5.1e-12 45.8 0.2 2.3 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 MarR_2 PF12802.2 EME28061.1 - 0.085 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 MarR family AIG1 PF04548.11 EME28062.1 - 6.2e-18 64.6 0.1 1e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EME28062.1 - 2.5e-08 33.8 0.1 4.8e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME28062.1 - 1e-07 31.9 4.1 0.0022 17.8 0.1 2.7 2 1 1 3 3 2 2 Dynamin family Septin PF00735.13 EME28062.1 - 9.9e-07 28.0 0.1 2.7e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Septin AAA_16 PF13191.1 EME28062.1 - 0.00046 20.2 0.1 0.0012 18.8 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 EME28062.1 - 0.001 18.6 0.3 0.24 10.8 0.0 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EME28062.1 - 0.0011 18.1 0.1 0.0026 16.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EME28062.1 - 0.0015 17.7 0.0 0.0037 16.4 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EME28062.1 - 0.0017 17.8 0.3 0.0035 16.8 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain DUF815 PF05673.8 EME28062.1 - 0.002 17.1 0.6 0.02 13.8 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF815) FeoB_N PF02421.13 EME28062.1 - 0.0021 17.3 0.0 0.0047 16.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B T2SE PF00437.15 EME28062.1 - 0.0023 16.8 0.1 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EME28062.1 - 0.0027 17.5 0.3 0.0064 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EME28062.1 - 0.0035 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EME28062.1 - 0.0036 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EME28062.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EME28062.1 - 0.0058 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EME28062.1 - 0.0088 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 EME28062.1 - 0.0088 15.7 0.1 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EME28062.1 - 0.0089 16.1 0.1 0.036 14.2 0.0 2.1 2 0 0 2 2 1 1 RNA helicase GTP_EFTU PF00009.22 EME28062.1 - 0.01 15.2 0.5 0.1 12.0 0.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EME28062.1 - 0.01 15.3 0.4 0.044 13.2 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EME28062.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EME28062.1 - 0.016 14.7 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DLIC PF05783.6 EME28062.1 - 0.019 13.6 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) KAP_NTPase PF07693.9 EME28062.1 - 0.029 13.3 0.1 0.077 11.9 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 EME28062.1 - 0.031 14.4 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EME28062.1 - 0.036 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EME28062.1 - 0.043 13.2 0.5 0.095 12.1 0.3 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EME28062.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME28062.1 - 0.058 14.2 0.1 0.12 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EME28062.1 - 0.083 13.0 0.1 0.19 11.9 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EME28062.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AIG1 PF04548.11 EME28063.1 - 5.5e-18 64.8 0.1 8.5e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EME28063.1 - 2.2e-08 34.0 0.1 4.1e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME28063.1 - 9e-08 32.1 4.2 0.002 18.0 0.1 2.6 2 1 1 3 3 2 2 Dynamin family Septin PF00735.13 EME28063.1 - 9.4e-07 28.1 0.2 2.1e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Septin AAA_16 PF13191.1 EME28063.1 - 0.0004 20.4 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 EME28063.1 - 0.00079 19.0 0.3 0.21 11.0 0.0 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EME28063.1 - 0.0011 18.2 0.1 0.0023 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EME28063.1 - 0.0013 17.9 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EME28063.1 - 0.0015 18.0 0.3 0.0031 16.9 0.2 1.6 1 1 0 1 1 1 1 AAA-like domain DUF815 PF05673.8 EME28063.1 - 0.0017 17.3 0.6 0.022 13.6 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) FeoB_N PF02421.13 EME28063.1 - 0.0018 17.5 0.0 0.0041 16.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B T2SE PF00437.15 EME28063.1 - 0.002 17.0 0.1 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EME28063.1 - 0.0027 17.6 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EME28063.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EME28063.1 - 0.0036 16.9 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EME28063.1 - 0.004 16.7 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EME28063.1 - 0.0054 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EME28063.1 - 0.0072 16.0 0.1 0.15 11.8 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EME28063.1 - 0.0084 15.6 0.3 0.039 13.4 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EME28063.1 - 0.0085 15.5 0.5 0.089 12.2 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EME28063.1 - 0.0087 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EME28063.1 - 0.0097 15.6 0.1 0.015 14.9 0.1 1.4 1 1 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EME28063.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EME28063.1 - 0.015 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DLIC PF05783.6 EME28063.1 - 0.017 13.7 0.0 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) KAP_NTPase PF07693.9 EME28063.1 - 0.025 13.5 0.1 0.068 12.1 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 EME28063.1 - 0.027 14.6 0.1 0.11 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EME28063.1 - 0.036 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EME28063.1 - 0.038 13.4 0.5 0.086 12.2 0.3 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EME28063.1 - 0.045 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME28063.1 - 0.051 14.4 0.1 0.12 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EME28063.1 - 0.071 13.3 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EME28063.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.8 EME28063.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_32 PF13654.1 EME28063.1 - 0.19 10.3 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyoxalase_4 PF13669.1 EME28064.1 - 8e-23 80.5 0.0 9.7e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EME28064.1 - 5.5e-12 45.7 0.0 6.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME28064.1 - 1.7e-11 44.6 0.0 2.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EME28064.1 - 3.9e-11 43.1 0.0 4.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TPR_7 PF13176.1 EME28064.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat XLF PF09302.6 EME28066.1 - 1.8e-10 40.8 2.1 1.8e-10 40.8 1.5 2.0 2 0 0 2 2 2 1 XLF (XRCC4-like factor) Ribosomal_L18e PF00828.14 EME28067.1 - 1.2e-09 38.5 0.0 4.3e-09 36.8 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L18e/L15 HIT PF01230.18 EME28068.1 - 8.8e-21 74.2 0.1 1.3e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME28068.1 - 0.00014 22.0 0.1 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EME28068.1 - 0.026 14.1 0.1 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Voldacs PF03517.8 EME28068.1 - 0.044 13.6 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling dsDNA_bind PF01984.15 EME28069.1 - 1.3e-26 92.6 8.8 1.5e-26 92.4 6.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4332 PF14229.1 EME28069.1 - 0.00061 19.7 0.6 0.00079 19.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) UPF0181 PF03701.9 EME28069.1 - 0.065 12.5 0.4 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Regulator_TrmB PF11495.3 EME28069.1 - 0.081 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Pex16 PF08610.5 EME28070.1 - 5.4e-31 107.8 8.2 2e-30 105.9 5.7 1.8 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Tic22 PF04278.7 EME28071.1 - 2.5e-24 86.0 1.7 7.4e-22 77.9 0.0 2.5 2 0 0 2 2 2 2 Tic22-like family Helicase_C PF00271.26 EME28072.1 - 1.9e-12 46.8 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 EME28073.1 - 2.8e-13 49.1 9.4 0.016 15.0 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat COX17 PF05051.8 EME28074.1 - 6.2e-24 83.7 12.5 9.1e-24 83.2 8.7 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) IF-2B PF01008.12 EME28075.1 - 4.4e-75 252.2 0.0 5.2e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PAP2 PF01569.16 EME28076.1 - 2.1e-20 72.6 1.2 2.1e-20 72.6 0.8 1.5 2 0 0 2 2 2 1 PAP2 superfamily Transmemb_17 PF09799.4 EME28076.1 - 0.026 14.8 1.6 0.026 14.8 1.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein DUF4117 PF13491.1 EME28076.1 - 0.091 12.2 3.9 0.15 11.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) E1-E2_ATPase PF00122.15 EME28077.1 - 6.2e-67 225.0 3.5 6.2e-67 225.0 2.4 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME28077.1 - 4e-48 163.3 10.2 4e-48 163.3 7.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME28077.1 - 1e-29 104.5 0.0 3e-28 99.7 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME28077.1 - 1.3e-17 63.0 0.0 1.3e-17 63.0 0.0 3.2 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EME28077.1 - 1.4e-16 61.2 0.1 1e-15 58.3 0.0 2.6 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME28077.1 - 5.3e-13 48.7 0.1 3.2e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME28077.1 - 1e-08 35.1 1.1 6.5e-06 25.8 1.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME28077.1 - 0.037 14.2 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 EME28078.1 - 6.4e-64 211.5 32.2 6e-14 51.4 0.2 7.7 2 1 7 10 10 10 9 TPR repeat TPR_1 PF00515.23 EME28078.1 - 1.8e-59 195.0 14.5 4.8e-08 32.2 0.2 10.9 11 0 0 11 11 10 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.1 EME28078.1 - 5.6e-54 182.8 0.0 6.3e-26 90.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.12 EME28078.1 - 5.9e-49 160.0 6.5 5.4e-06 25.9 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EME28078.1 - 6.1e-42 138.3 16.4 1.6e-07 30.9 0.0 8.5 9 0 0 9 9 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EME28078.1 - 3.3e-38 129.4 14.1 7.6e-10 38.5 0.3 7.2 2 1 6 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 EME28078.1 - 1.3e-33 112.2 10.3 7.2e-05 22.2 0.2 9.8 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 EME28078.1 - 1.4e-30 102.6 8.0 0.00024 20.6 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME28078.1 - 7.9e-26 90.1 0.9 1.9e-05 25.1 0.0 6.5 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME28078.1 - 1.8e-24 84.0 0.0 0.0096 16.4 0.0 9.0 1 1 8 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME28078.1 - 1.3e-20 73.4 0.9 0.0048 17.2 0.1 7.4 5 2 2 8 8 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EME28078.1 - 1.6e-16 59.5 0.3 0.11 13.0 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME28078.1 - 1.4e-14 53.4 18.1 0.0098 15.7 0.2 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EME28078.1 - 2.6e-11 43.2 2.7 0.00016 21.4 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 EME28078.1 - 1.4e-10 40.8 24.1 2.1e-05 23.8 0.3 6.8 4 2 2 6 6 6 3 Est1 DNA/RNA binding domain NARP1 PF12569.3 EME28078.1 - 9e-09 34.6 2.8 0.0053 15.5 0.0 3.4 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 Sel1 PF08238.7 EME28078.1 - 6.5e-05 23.4 6.0 22 5.8 0.0 6.9 8 0 0 8 8 7 0 Sel1 repeat TPR_4 PF07721.9 EME28078.1 - 0.0019 18.4 0.1 33 5.3 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF632 PF04782.7 EME28078.1 - 0.0028 16.8 0.4 0.43 9.6 0.1 2.7 3 0 0 3 3 2 1 Protein of unknown function (DUF632) Apc3 PF12895.2 EME28078.1 - 0.0031 17.6 10.7 2.2 8.4 0.1 4.6 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 EME28078.1 - 0.017 14.5 4.8 0.7 9.3 0.2 3.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF357 PF04010.8 EME28078.1 - 0.028 14.1 0.8 1.2 8.8 0.1 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF357) MIT PF04212.13 EME28078.1 - 0.056 13.3 16.7 6.1 6.8 0.0 6.9 8 1 1 9 9 7 0 MIT (microtubule interacting and transport) domain DUF4162 PF13732.1 EME28078.1 - 7.8 7.0 8.3 12 6.5 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) VWA_2 PF13519.1 EME28080.1 - 1.4e-06 28.5 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EME28080.1 - 1.4e-06 28.0 0.0 3.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.7 EME28080.1 - 2.5e-05 22.4 0.1 5.6e-05 21.2 0.1 1.6 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MFS_1 PF07690.11 EME28081.1 - 2.2e-28 99.0 41.6 2.2e-28 99.0 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME28081.1 - 5.5e-09 35.1 3.3 5.5e-09 35.1 2.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Urm1 PF09138.6 EME28082.1 - 3.6 7.7 6.3 39 4.4 0.8 3.1 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) DIE2_ALG10 PF04922.7 EME28083.1 - 6e-42 144.0 33.3 9.2e-42 143.4 23.1 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family RF-1 PF00472.15 EME28084.1 - 1.5e-33 114.9 0.6 1.5e-33 114.9 0.4 2.0 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EME28084.1 - 8.3e-24 83.5 0.2 8.3e-24 83.5 0.1 2.4 2 1 0 2 2 2 1 PCRF domain HSBP1 PF06825.7 EME28084.1 - 0.056 13.0 0.1 0.24 11.0 0.1 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DASH_Dad3 PF08656.5 EME28084.1 - 0.87 9.3 10.9 11 5.7 0.3 3.4 2 1 1 3 3 3 0 DASH complex subunit Dad3 DUF342 PF03961.8 EME28084.1 - 2.2 6.6 8.3 0.81 8.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 EME28084.1 - 5.7 7.7 10.4 3.4 8.4 1.2 3.0 2 1 1 3 3 3 0 Occludin homology domain V_ATPase_I PF01496.14 EME28084.1 - 7.8 4.2 7.5 0.83 7.4 2.2 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NT-C2 PF10358.4 EME28085.1 - 2.6e-09 36.7 0.0 5.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF334 PF03904.8 EME28085.1 - 0.36 10.1 4.4 1.2 8.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF334) AATF-Che1 PF13339.1 EME28085.1 - 0.64 10.1 7.8 0.31 11.1 1.2 2.7 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor Hydrolase_3 PF08282.7 EME28086.1 - 1.9e-52 178.4 0.0 2.7e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LdpA_C PF12617.3 EME28086.1 - 3.6e-46 156.7 0.0 6.2e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Iron-Sulfur binding protein C terminal S6PP PF05116.8 EME28086.1 - 1.3e-12 47.5 0.0 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Fer4_7 PF12838.2 EME28086.1 - 5.8e-07 29.7 6.7 2.1e-06 28.0 4.6 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EME28086.1 - 7.7e-07 28.7 21.1 9.1e-05 22.1 2.5 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Hydrolase PF00702.21 EME28086.1 - 3.6e-05 24.2 0.0 0.0024 18.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fer4 PF00037.22 EME28086.1 - 4.5e-05 22.8 4.6 4.5e-05 22.8 3.2 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_9 PF13187.1 EME28086.1 - 6e-05 23.2 7.1 6e-05 23.2 4.9 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EME28086.1 - 0.00034 20.4 6.8 0.00034 20.4 4.7 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EME28086.1 - 0.0011 18.6 25.5 0.0018 18.0 2.7 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EME28086.1 - 0.0012 18.6 2.5 0.0012 18.6 1.7 3.1 3 0 0 3 3 2 1 4Fe-4S binding domain HAD PF12710.2 EME28086.1 - 0.0031 17.7 0.0 0.041 14.0 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Fer4_16 PF13484.1 EME28086.1 - 0.0041 17.8 9.9 0.016 15.9 0.9 2.9 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.1 EME28086.1 - 0.01 16.2 2.9 0.01 16.2 2.0 3.3 3 1 1 4 4 4 0 4Fe-4S dicluster domain Trehalose_PPase PF02358.11 EME28086.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase Hydrolase_6 PF13344.1 EME28086.1 - 0.017 14.9 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Fer4_17 PF13534.1 EME28086.1 - 0.054 13.8 0.5 0.054 13.8 0.3 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EME28086.1 - 4.6 7.3 16.5 0.066 13.2 3.0 2.7 1 1 2 3 3 2 0 4Fe-4S dicluster domain NmrA PF05368.8 EME28087.1 - 8.1e-47 159.4 0.0 9.8e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME28087.1 - 1.8e-10 41.1 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME28087.1 - 1.2e-06 27.4 0.0 1.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME28087.1 - 0.00057 19.3 0.0 0.00084 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EME28087.1 - 0.0094 15.9 0.1 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 EME28087.1 - 0.018 15.4 0.1 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EME28087.1 - 0.099 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Pkinase PF00069.20 EME28088.1 - 8.8e-64 215.1 0.0 1.6e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28088.1 - 7.5e-33 113.6 0.0 1.3e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME28088.1 - 2.9e-05 23.1 0.0 6.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like EF-hand_7 PF13499.1 EME28088.1 - 2.9e-05 24.0 4.5 0.042 13.9 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain pair APH PF01636.18 EME28088.1 - 0.00075 19.2 0.3 0.0049 16.6 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family EF-hand_6 PF13405.1 EME28088.1 - 0.0021 17.7 3.0 5.5 7.1 0.0 5.2 5 0 0 5 5 5 1 EF-hand domain FlgM PF04316.8 EME28088.1 - 0.24 11.3 3.4 10 6.1 0.1 3.7 3 1 1 4 4 4 0 Anti-sigma-28 factor, FlgM EF-hand_1 PF00036.27 EME28088.1 - 0.29 10.5 5.4 8.3 5.9 0.0 4.3 5 0 0 5 5 5 0 EF hand Peptidase_C97 PF05903.9 EME28089.1 - 3.4e-39 134.0 0.1 4.2e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EME28089.1 - 0.062 13.2 0.1 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Tim17 PF02466.14 EME28090.1 - 1.4e-09 38.0 8.6 1.8e-09 37.7 6.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EME28090.1 - 2.5e-06 27.5 4.5 2.5e-06 27.5 3.1 2.0 3 0 0 3 3 3 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EME28090.1 - 0.018 14.6 5.1 0.018 14.6 3.5 2.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EME28090.1 - 0.31 10.6 5.7 0.19 11.4 0.3 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EME28090.1 - 3.1 7.3 14.0 0.1 12.1 3.4 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Thioredoxin PF00085.15 EME28091.1 - 1.7e-21 75.8 0.2 3.8e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EME28091.1 - 1.5e-07 31.4 0.1 6.7e-06 26.1 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME28091.1 - 6.7e-07 29.5 0.9 7e-06 26.2 0.1 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EME28091.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EME28091.1 - 0.00029 20.5 0.9 0.0011 18.6 0.1 2.2 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EME28091.1 - 0.0023 17.4 1.3 0.0036 16.8 0.1 1.9 2 1 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EME28091.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF2847 PF11009.3 EME28091.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.6 EME28091.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 EME28091.1 - 0.16 11.9 0.7 8.8 6.3 0.0 2.7 1 1 2 3 3 3 0 Thioredoxin Glutaredoxin PF00462.19 EME28091.1 - 1 9.4 5.7 0.84 9.6 0.1 2.8 2 1 1 3 3 3 0 Glutaredoxin SAPS PF04499.10 EME28092.1 - 6.2e-07 28.4 3.7 6.2e-07 28.4 2.6 4.9 3 1 1 5 5 5 2 SIT4 phosphatase-associated protein LETM1 PF07766.8 EME28093.1 - 4.6e-88 294.7 1.1 4.6e-88 294.7 0.8 2.8 2 1 2 4 4 4 1 LETM1-like protein EF-hand_1 PF00036.27 EME28093.1 - 1.1e-08 33.7 1.3 0.00084 18.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EME28093.1 - 1.2e-08 34.9 2.0 1e-07 32.0 0.5 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EME28093.1 - 5.6e-06 25.8 1.4 0.2 11.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EME28093.1 - 0.00019 20.6 3.0 0.0052 16.0 0.4 2.8 2 0 0 2 2 2 1 EF hand RPA_C PF08784.6 EME28093.1 - 0.059 13.7 2.5 11 6.5 0.1 3.9 3 1 1 4 4 4 0 Replication protein A C terminal EF-hand_8 PF13833.1 EME28093.1 - 0.07 12.7 2.0 0.56 9.8 0.4 2.9 1 1 1 2 2 2 0 EF-hand domain pair SAP PF02037.22 EME28093.1 - 0.28 10.7 6.9 1.1 8.8 0.0 3.7 4 0 0 4 4 4 0 SAP domain LETM1 PF07766.8 EME28094.1 - 2.1e-87 292.5 1.1 2.1e-87 292.5 0.8 2.8 2 1 2 4 4 4 1 LETM1-like protein EF-hand_7 PF13499.1 EME28094.1 - 1.1e-08 35.0 1.9 1e-07 32.0 0.5 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EME28094.1 - 1.1e-08 33.6 1.3 0.00084 18.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EME28094.1 - 5.6e-06 25.8 1.4 0.2 11.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EME28094.1 - 0.00019 20.6 3.0 0.0052 16.0 0.4 2.8 2 0 0 2 2 2 1 EF hand RPA_C PF08784.6 EME28094.1 - 0.06 13.7 2.5 11 6.5 0.1 3.9 3 1 1 4 4 4 0 Replication protein A C terminal EF-hand_8 PF13833.1 EME28094.1 - 0.064 12.8 2.0 0.56 9.8 0.4 3.0 1 1 1 2 2 2 0 EF-hand domain pair SAP PF02037.22 EME28094.1 - 1 8.9 7.1 1.1 8.8 0.0 3.6 4 0 0 4 4 4 0 SAP domain GCD14 PF08704.5 EME28095.1 - 0.0031 17.0 3.7 0.0045 16.5 2.6 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DUF1395 PF07160.7 EME28095.1 - 0.006 16.1 1.3 0.0088 15.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) NDUF_B7 PF05676.8 EME28095.1 - 0.034 13.5 0.5 0.06 12.7 0.4 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Inhibitor_I71 PF12628.2 EME28095.1 - 0.067 12.8 1.8 0.09 12.4 1.2 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Band_3_cyto PF07565.8 EME28095.1 - 0.079 12.4 0.8 0.09 12.2 0.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CHCH PF06747.8 EME28095.1 - 0.14 12.1 1.7 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 CHCH domain tRNA_int_end_N2 PF12928.2 EME28096.1 - 1.4e-13 50.0 0.0 2.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Glyco_hydro_4 PF02056.11 EME28096.1 - 0.028 13.7 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase tRNA_int_endo PF01974.12 EME28096.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_end_N2 PF12928.2 EME28097.1 - 1.4e-13 50.0 0.0 2.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Glyco_hydro_4 PF02056.11 EME28097.1 - 0.03 13.6 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase tRNA_int_endo PF01974.12 EME28097.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain MatE PF01554.13 EME28098.1 - 3.2e-37 127.6 30.1 2.3e-24 85.8 8.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EME28098.1 - 3e-11 43.3 2.9 3e-11 43.3 2.0 4.2 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EME28099.1 - 1e-29 103.2 25.9 1.9e-24 86.0 8.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EME28099.1 - 2.6e-11 43.4 2.9 2.6e-11 43.4 2.0 3.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain TRAPP PF04051.11 EME28101.1 - 5.5e-38 129.8 0.2 7e-38 129.5 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FtsJ PF01728.14 EME28102.1 - 6e-52 176.2 0.3 1.3e-51 175.1 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase WGG PF10273.4 EME28102.1 - 3.4e-06 27.0 0.4 7.5e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NSP13 PF06460.7 EME28102.1 - 0.03 13.1 0.0 0.067 12.0 0.0 1.5 1 0 0 1 1 1 0 Coronavirus NSP13 Prenyltransf PF01255.14 EME28102.1 - 0.063 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Mpv17_PMP22 PF04117.7 EME28103.1 - 2.6e-15 55.7 2.8 6.1e-15 54.6 1.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cytochrome_CBB3 PF13442.1 EME28103.1 - 3.3e-13 49.5 0.0 5.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EME28103.1 - 1.7e-05 25.5 0.2 4.4e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 EME28103.1 - 0.0011 18.4 1.1 0.014 14.8 0.2 2.2 1 1 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 EME28103.1 - 0.039 13.6 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Haem-binding domain Mpv17_PMP22 PF04117.7 EME28104.1 - 2.6e-15 55.8 2.8 6.5e-15 54.5 1.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cytochrome_CBB3 PF13442.1 EME28104.1 - 1.1e-11 44.7 0.0 2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EME28104.1 - 0.0023 18.7 0.3 0.0057 17.4 0.2 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 EME28104.1 - 0.0063 15.9 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.1 EME28104.1 - 0.052 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Haem-binding domain Glyoxalase_2 PF12681.2 EME28105.1 - 5e-11 43.1 0.0 6.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EME28105.1 - 9.8e-10 38.4 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EME28105.1 - 1.2e-09 38.1 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HECT PF00632.20 EME28106.1 - 4e-87 292.3 0.1 7.8e-87 291.3 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 EME28106.1 - 8.3e-55 182.8 12.5 2.6e-09 37.1 0.3 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME28106.1 - 8e-32 108.1 40.8 2.3e-07 30.2 0.1 8.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.11 EME28107.1 - 5.8e-12 45.0 23.7 5.8e-12 45.0 16.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EME28107.1 - 0.00014 20.5 6.6 0.00014 20.5 4.6 2.2 1 1 0 2 2 2 1 Vacuole effluxer Atg22 like Orbi_NS3 PF01616.11 EME28107.1 - 0.014 14.3 0.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Orbivirus NS3 Pkinase PF00069.20 EME28108.1 - 3.6e-18 65.6 0.2 6.5e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28108.1 - 4.9e-14 52.0 0.1 8.8e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EME28108.1 - 4.9e-11 42.8 0.1 9.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME28108.1 - 7.1e-10 38.1 0.1 7.3e-08 31.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EME28108.1 - 2.2e-08 34.3 0.2 9e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME28108.1 - 1.3e-07 31.6 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME28108.1 - 5.6e-06 26.1 0.1 0.00023 21.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ribosomal_L12 PF00542.14 EME28109.1 - 4e-24 84.3 8.6 4e-24 84.3 6.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain CM_1 PF07736.6 EME28109.1 - 0.032 14.3 0.3 0.17 11.9 0.1 2.1 1 1 1 2 2 2 0 Chorismate mutase type I SOG2 PF10428.4 EME28109.1 - 0.042 12.5 0.1 0.042 12.5 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2267 PF10025.4 EME28109.1 - 0.071 13.1 0.3 0.15 12.1 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) VitD-bind_III PF09164.5 EME28110.1 - 0.1 12.2 0.2 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Lsr2 PF11774.3 EME28110.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.0 1 0 0 1 1 1 0 Lsr2 Ribosomal_S7 PF00177.16 EME28111.1 - 8.2e-43 145.5 0.9 9.8e-43 145.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAD_binding_6 PF00970.19 EME28115.1 - 8.5e-29 99.6 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EME28115.1 - 5.7e-26 91.2 0.0 8.3e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EME28115.1 - 0.00032 20.6 0.0 0.0049 16.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EME28115.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Sugar_tr PF00083.19 EME28116.1 - 4.4e-14 51.9 6.6 6.5e-13 48.0 4.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Glycolytic PF00274.14 EME28118.1 - 7.4e-110 366.6 0.0 1.2e-109 365.8 0.0 1.3 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-I TFR_dimer PF04253.10 EME28118.1 - 0.024 14.2 0.0 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain AP_endonuc_2 PF01261.19 EME28119.1 - 1.6e-25 89.6 0.0 2.1e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 EME28119.1 - 0.0066 15.9 0.0 0.046 13.2 0.0 2.2 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus Prion_bPrPp PF11587.3 EME28121.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal ThiF PF00899.16 EME28122.1 - 3.5e-53 179.0 1.4 1.5e-32 112.2 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EME28122.1 - 7.7e-41 139.1 0.0 4e-40 136.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EME28122.1 - 4.8e-37 125.3 0.3 3.8e-24 84.0 0.0 3.4 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EME28122.1 - 3.5e-24 83.9 2.2 3.6e-20 71.0 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EME28122.1 - 0.051 13.1 0.1 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 MoeZ/MoeB domain adh_short PF00106.20 EME28122.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EME28122.1 - 0.12 11.5 0.1 13 4.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Wbp11 PF09429.5 EME28123.1 - 0.0001 22.1 9.0 0.00019 21.3 5.7 1.9 1 1 0 1 1 1 1 WW domain binding protein 11 DUF2638 PF10937.3 EME28123.1 - 0.08 13.9 1.1 0.17 12.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DUF2924 PF11149.3 EME28123.1 - 0.16 12.0 2.9 0.36 10.8 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) LNP1 PF15419.1 EME28123.1 - 0.74 9.8 6.7 1.5 8.9 1.6 2.4 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 COQ7 PF03232.8 EME28124.1 - 4.3e-64 215.1 1.8 1.1e-63 213.7 1.3 1.7 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 CTNNBL PF08216.6 EME28124.1 - 5.4e-20 70.9 1.0 2.2e-19 69.0 0.0 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Rubrerythrin PF02915.12 EME28124.1 - 0.0032 17.7 3.8 0.0032 17.7 2.6 2.9 2 1 1 3 3 3 1 Rubrerythrin XH PF03469.9 EME28124.1 - 0.15 11.7 4.2 1.2 8.7 0.0 3.0 2 1 1 3 3 3 0 XH domain SURF1 PF02104.10 EME28125.1 - 1.9e-42 145.5 0.0 2.3e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Btz PF09405.5 EME28126.1 - 0.0078 16.2 1.2 0.012 15.6 0.8 1.3 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding RloB PF13707.1 EME28126.1 - 0.069 12.8 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 RloB-like protein RRM_1 PF00076.17 EME28127.1 - 2.4e-13 49.4 0.0 4.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28127.1 - 1.2e-09 37.9 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME28127.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EME28127.1 - 0.012 15.6 0.3 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding DUF547 PF04784.9 EME28129.1 - 7.2e-24 83.9 0.0 1.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.16 EME28129.1 - 3.6e-17 61.8 0.0 6.3e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribosomal_L14e PF01929.12 EME28130.1 - 1.7e-28 98.7 2.3 2.2e-28 98.4 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EME28130.1 - 9.1e-05 22.0 5.1 9.1e-05 22.0 3.5 2.0 2 0 0 2 2 2 1 KOW motif YceG PF02618.11 EME28130.1 - 0.096 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 YceG-like family KH_1 PF00013.24 EME28131.1 - 1.3e-54 181.6 17.0 5e-17 61.3 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EME28131.1 - 9.8e-39 130.4 18.8 1.4e-11 43.7 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 EME28131.1 - 2.2e-21 75.1 6.3 2.9e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EME28131.1 - 8.8e-14 50.9 4.9 0.029 13.9 0.0 4.8 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 EME28131.1 - 3.9e-07 29.7 11.6 0.11 12.2 0.0 5.3 5 1 0 5 5 5 4 NusA-like KH domain DUF1598 PF07643.6 EME28131.1 - 0.075 13.0 0.5 1 9.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1598) Secretin_N PF03958.12 EME28131.1 - 0.077 13.1 2.4 3.2 8.0 0.0 3.4 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain KH_1 PF00013.24 EME28132.1 - 1.3e-54 181.6 17.0 5e-17 61.3 0.1 4.4 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 EME28132.1 - 9.8e-39 130.4 18.8 1.4e-11 43.7 0.1 4.7 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 EME28132.1 - 2.2e-21 75.1 6.3 2.9e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EME28132.1 - 8.8e-14 50.9 4.9 0.029 13.9 0.0 4.8 4 0 0 4 4 4 4 KH domain KH_5 PF13184.1 EME28132.1 - 3.9e-07 29.7 11.6 0.11 12.2 0.0 5.3 5 1 0 5 5 5 4 NusA-like KH domain DUF1598 PF07643.6 EME28132.1 - 0.075 13.0 0.5 1 9.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1598) Secretin_N PF03958.12 EME28132.1 - 0.077 13.1 2.4 3.2 8.0 0.0 3.4 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain HCNGP PF07818.8 EME28133.1 - 1.2e-20 73.3 0.0 2.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein CENP-Q PF13094.1 EME28134.1 - 0.00072 19.6 23.7 0.0012 18.8 16.4 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 EME28134.1 - 0.0012 18.3 17.3 0.0017 17.9 12.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2508 PF10704.4 EME28134.1 - 0.0033 17.5 0.1 0.0033 17.5 0.1 3.7 2 1 0 2 2 1 1 Protein of unknown function (DUF2508) DUF342 PF03961.8 EME28134.1 - 0.0054 15.2 11.2 0.0067 14.8 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Atg14 PF10186.4 EME28134.1 - 0.025 13.5 12.6 0.038 12.9 8.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EME28134.1 - 0.03 13.3 16.2 0.046 12.7 11.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EME28134.1 - 0.031 11.6 16.5 0.042 11.1 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Borrelia_P83 PF05262.6 EME28134.1 - 0.1 10.8 12.6 0.13 10.4 8.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HAUS-augmin3 PF14932.1 EME28134.1 - 0.13 11.4 17.7 0.21 10.7 12.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TauE PF01925.14 EME28134.1 - 0.16 11.3 6.9 0.23 10.8 4.8 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2968 PF11180.3 EME28134.1 - 0.19 11.0 14.4 0.42 9.9 10.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) OmpH PF03938.9 EME28134.1 - 0.2 11.5 16.4 0.38 10.6 11.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) VIT1 PF01988.14 EME28134.1 - 0.58 9.6 11.6 15 5.0 8.0 2.5 1 1 1 2 2 2 0 VIT family DUF1664 PF07889.7 EME28134.1 - 0.75 9.5 10.8 0.44 10.3 4.9 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 EME28134.1 - 1.7 8.5 21.4 0.73 9.7 12.9 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GrpE PF01025.14 EME28134.1 - 1.7 8.1 23.4 2.9 7.3 5.8 2.2 1 1 1 2 2 2 0 GrpE DUF4613 PF15390.1 EME28134.1 - 1.7 6.6 9.2 2.2 6.3 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Tox-ODYAM1 PF15642.1 EME28134.1 - 1.8 7.1 11.2 2.8 6.5 7.7 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cob_adeno_trans PF01923.13 EME28134.1 - 2.8 7.7 10.3 0.59 9.9 0.4 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF883 PF05957.8 EME28134.1 - 5.4 7.4 8.9 47 4.4 5.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.3 EME28134.1 - 6.1 6.0 17.4 7.2 5.7 11.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_23 PF13476.1 EME28136.1 - 2.2e-26 93.4 7.3 2.2e-26 93.4 5.0 8.6 1 1 1 2 2 2 1 AAA domain SbcCD_C PF13558.1 EME28136.1 - 2e-10 40.4 0.0 7.4e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EME28136.1 - 5.1e-07 29.9 23.6 0.00089 19.2 2.9 4.6 3 1 0 4 4 4 2 AAA domain SMC_N PF02463.14 EME28136.1 - 2.4e-06 26.9 0.0 2.4e-06 26.9 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME28136.1 - 0.0024 17.8 10.1 0.11 12.4 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EME28136.1 - 0.0033 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EME28136.1 - 0.012 14.1 0.0 0.012 14.1 0.0 8.6 1 1 7 9 9 9 0 AAA domain AAA_19 PF13245.1 EME28136.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EME28136.1 - 0.47 9.5 40.0 0.34 10.0 2.0 6.6 3 2 4 7 7 7 0 Reovirus sigma C capsid protein MARVEL PF01284.18 EME28137.1 - 0.094 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain DnaJ_CXXCXGXG PF00684.14 EME28138.1 - 0.0023 17.9 16.5 0.039 14.0 5.4 3.4 3 1 1 4 4 4 3 DnaJ central domain zf-HIT PF04438.11 EME28138.1 - 0.094 12.3 8.7 1.3 8.7 0.5 2.4 2 0 0 2 2 2 0 HIT zinc finger DUF1356 PF07092.7 EME28138.1 - 0.33 10.1 8.1 0.13 11.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) S1 PF00575.18 EME28139.1 - 1.6e-44 149.8 3.8 2.4e-19 69.1 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain S1_2 PF13509.1 EME28139.1 - 0.14 12.1 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 S1 domain BioY PF02632.9 EME28139.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 BioY family Pept_tRNA_hydro PF01195.14 EME28140.1 - 3e-54 183.3 0.0 4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase UQ_con PF00179.21 EME28141.1 - 2.7e-27 94.9 0.0 3.2e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME28141.1 - 3.6e-05 23.5 0.0 4.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 EME28141.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EME28141.1 - 0.017 15.0 0.1 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EME28141.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Methyltransf_4 PF02390.12 EME28142.1 - 2.8e-43 147.2 0.0 3.4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME28142.1 - 6.2e-05 22.4 0.1 0.00052 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME28142.1 - 0.00026 21.0 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28142.1 - 0.0006 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28142.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EME28142.1 - 0.0021 17.4 0.0 0.0049 16.1 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.7 EME28142.1 - 0.0021 18.5 0.0 0.0069 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28142.1 - 0.0039 17.7 0.0 0.0076 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28142.1 - 0.0043 16.8 0.0 0.2 11.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain AAA_33 PF13671.1 EME28143.1 - 2.3e-12 46.9 0.3 2.6e-09 37.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EME28143.1 - 4.2e-12 45.8 0.0 4.7e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_18 PF13238.1 EME28143.1 - 6.8e-06 26.4 0.3 0.00028 21.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EME28143.1 - 7.5e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EME28143.1 - 0.0002 22.1 0.2 0.00074 20.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28143.1 - 0.00028 21.0 0.0 0.00093 19.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME28143.1 - 0.0013 18.9 0.1 0.0041 17.2 0.0 1.9 2 0 0 2 2 1 1 RNA helicase ABC_tran PF00005.22 EME28143.1 - 0.0054 17.0 0.1 0.012 15.9 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA PF00004.24 EME28143.1 - 0.0096 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EME28143.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EME28143.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EME28143.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EME28143.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family RRM_3 PF08777.6 EME28143.1 - 0.025 14.4 0.6 0.051 13.4 0.2 1.7 2 0 0 2 2 1 0 RNA binding motif AAA_28 PF13521.1 EME28143.1 - 0.026 14.4 0.1 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME28143.1 - 0.027 13.6 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 EME28143.1 - 0.044 13.5 0.1 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EME28143.1 - 0.046 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Thymidylate_kin PF02223.12 EME28143.1 - 0.059 12.7 0.2 6.7 6.0 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase SKI PF01202.17 EME28143.1 - 0.074 12.9 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase ArgK PF03308.11 EME28143.1 - 0.093 11.4 0.3 0.17 10.5 0.0 1.5 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EME28143.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ADK PF00406.17 EME28143.1 - 0.12 12.2 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase AAA_25 PF13481.1 EME28143.1 - 0.12 11.7 1.1 0.36 10.2 0.1 2.1 2 1 1 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EME28143.1 - 0.16 11.4 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PsbQ PF05757.6 EME28144.1 - 1.2e-08 34.6 3.9 2.7e-08 33.4 2.2 1.7 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) DNA_pol_lambd_f PF10391.4 EME28144.1 - 0.031 13.8 1.9 0.054 13.0 0.4 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda LEDGF PF11467.3 EME28144.1 - 0.077 12.7 1.4 0.16 11.6 1.0 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) RsbRD_N PF14361.1 EME28144.1 - 0.08 13.3 0.8 0.26 11.7 0.6 1.9 1 1 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Phage_Coat_B PF05356.6 EME28144.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage Coat protein B zf-RING_2 PF13639.1 EME28145.1 - 1.4e-12 47.2 5.8 1.4e-12 47.2 4.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME28145.1 - 8.9e-12 44.9 1.6 1.8e-11 43.9 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME28145.1 - 2.1e-08 33.9 0.7 3.7e-08 33.1 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EME28145.1 - 2.6e-08 33.3 6.5 5.8e-08 32.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28145.1 - 6.3e-08 32.5 6.6 1.2e-07 31.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28145.1 - 1.7e-07 30.8 4.7 3.1e-07 30.0 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME28145.1 - 2.4e-05 23.9 3.2 5e-05 22.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME28145.1 - 0.00012 21.6 1.9 0.00022 20.8 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EME28145.1 - 0.00057 19.3 3.4 0.0011 18.3 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EME28145.1 - 0.00059 19.6 4.8 0.00059 19.6 3.3 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING DZR PF12773.2 EME28145.1 - 0.0088 15.8 2.4 0.23 11.3 0.2 2.4 2 0 0 2 2 2 1 Double zinc ribbon RINGv PF12906.2 EME28145.1 - 0.18 11.8 4.7 0.38 10.8 3.3 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME28145.1 - 0.18 11.7 8.1 0.11 12.4 3.4 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain RecR PF02132.10 EME28145.1 - 0.29 10.5 3.5 0.54 9.7 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-RING_4 PF14570.1 EME28145.1 - 0.86 9.2 7.4 5.9 6.5 0.2 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Fer2 PF00111.22 EME28146.1 - 7.4e-10 38.4 0.8 1.3e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RCC1 PF00415.13 EME28148.1 - 5.4e-62 205.8 19.2 1.5e-09 37.8 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME28148.1 - 2.9e-33 112.7 42.1 4.5e-07 29.3 2.9 7.7 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EME28148.1 - 0.059 12.8 4.7 8.5 5.9 0.0 4.7 5 0 0 5 5 5 0 Putative carbohydrate binding domain DUF3228 PF11539.3 EME28150.1 - 3e-56 189.6 0.3 3.5e-56 189.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Peptidase_S9_N PF02897.10 EME28151.1 - 4e-95 318.8 4.0 5.1e-95 318.4 2.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EME28151.1 - 7.2e-61 205.1 0.0 1e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EME28151.1 - 0.0012 18.4 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EME28151.1 - 0.0015 18.0 0.0 0.016 14.6 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAE PF03283.8 EME28151.1 - 0.25 9.9 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_S9_N PF02897.10 EME28152.1 - 3.8e-95 318.8 4.0 4.9e-95 318.5 2.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EME28152.1 - 7.1e-61 205.1 0.0 9.9e-61 204.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EME28152.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EME28152.1 - 0.0014 18.0 0.0 0.016 14.6 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAE PF03283.8 EME28152.1 - 0.24 9.9 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Myb_DNA-binding PF00249.26 EME28153.1 - 5.1e-12 45.6 1.0 8.5e-12 44.9 0.7 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28153.1 - 0.0021 18.1 0.6 0.0021 18.1 0.4 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_S10 PF00338.17 EME28153.1 - 0.13 12.1 2.5 0.2 11.5 0.2 2.3 2 1 1 3 3 3 0 Ribosomal protein S10p/S20e Aldedh PF00171.17 EME28154.1 - 2.5e-138 461.2 0.0 3e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME28154.1 - 5.4e-09 35.2 0.0 1.1e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PhoU_div PF01865.11 EME28154.1 - 0.056 12.5 0.3 8 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF47 RF-1 PF00472.15 EME28155.1 - 3.5e-33 113.7 4.9 8.6e-33 112.5 0.4 2.4 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EME28155.1 - 1.6e-30 105.1 1.0 4.3e-30 103.7 0.1 2.1 1 1 1 2 2 2 1 PCRF domain TFIIS_C PF01096.13 EME28156.1 - 1.1e-21 76.1 3.7 1.1e-21 76.1 2.5 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EME28156.1 - 0.00011 21.9 1.6 0.00011 21.9 1.1 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EME28156.1 - 0.0012 18.4 1.4 0.0012 18.4 1.0 2.2 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 EME28156.1 - 0.0045 16.3 0.9 0.0045 16.3 0.6 2.4 2 1 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Tnp_zf-ribbon_2 PF13842.1 EME28156.1 - 0.01 16.2 5.6 1.1 9.7 0.6 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Terminase_GpA PF05876.7 EME28156.1 - 0.031 12.6 2.4 0.04 12.2 1.7 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 EME28156.1 - 0.057 12.7 0.1 0.057 12.7 0.1 2.3 2 1 1 3 3 3 0 TFIIB zinc-binding DUF2296 PF10058.4 EME28156.1 - 0.068 12.9 9.5 0.6 9.8 1.5 3.0 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) PhnA_Zn_Ribbon PF08274.7 EME28156.1 - 0.11 12.2 7.8 0.11 12.2 1.3 3.0 2 1 1 3 3 3 0 PhnA Zinc-Ribbon DUF2387 PF09526.5 EME28156.1 - 0.14 12.0 0.4 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 EME28156.1 - 0.15 11.8 7.5 4.9 7.0 1.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EME28156.1 - 0.38 10.6 9.0 4.8 7.1 0.0 3.8 4 0 0 4 4 4 0 Rubredoxin Lar_restr_allev PF14354.1 EME28156.1 - 0.41 10.9 3.9 1.6 9.0 0.4 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.8 EME28156.1 - 0.72 9.5 5.2 1 9.0 0.3 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EME28156.1 - 0.75 9.9 8.4 2.2e+02 2.1 5.8 2.5 1 1 0 1 1 1 0 CHY zinc finger zinc_ribbon_2 PF13240.1 EME28156.1 - 1.2 8.7 7.4 8.8 5.9 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_3 PF14369.1 EME28156.1 - 1.4 8.9 0.1 1.4 8.9 0.1 3.4 3 1 0 3 3 3 0 zinc-finger Rpr2 PF04032.11 EME28156.1 - 1.8 8.5 6.6 1.1e+02 2.7 4.6 2.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_4 PF13717.1 EME28156.1 - 2 8.1 9.2 5.4 6.7 1.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EME28156.1 - 2.1 8.0 9.2 2.9 7.5 0.7 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Fer4_8 PF13183.1 EME28156.1 - 2.3 8.3 5.2 18 5.4 3.6 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain C1_4 PF07975.7 EME28156.1 - 2.9 7.9 9.0 13 5.8 1.1 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain HypA PF01155.14 EME28156.1 - 3.4 7.3 6.9 3.7 7.2 1.6 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Mu-like_Com PF10122.4 EME28156.1 - 3.7 6.6 5.8 27 3.9 0.2 3.1 3 0 0 3 3 3 0 Mu-like prophage protein Com PHD PF00628.24 EME28156.1 - 9.1 6.0 9.8 17 5.1 0.8 2.8 2 2 0 2 2 2 0 PHD-finger TatD_DNase PF01026.16 EME28158.1 - 6.3e-49 166.4 0.1 7.5e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase TatD_DNase PF01026.16 EME28159.1 - 6.3e-49 166.4 0.1 7.5e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PK PF00224.16 EME28160.1 - 1.6e-111 372.2 0.0 2.3e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EME28160.1 - 3.5e-25 87.8 0.2 9.6e-25 86.4 0.0 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 EME28160.1 - 0.0014 17.6 0.1 0.0051 15.7 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Oxidored_nitro PF00148.14 EME28160.1 - 0.02 13.5 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase HpcH_HpaI PF03328.9 EME28160.1 - 0.024 13.4 0.1 0.052 12.4 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family TF_Zn_Ribbon PF08271.7 EME28161.1 - 0.00015 20.9 4.5 0.00033 19.9 3.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding KASH PF10541.4 EME28161.1 - 0.0085 15.9 1.3 0.022 14.5 0.9 1.6 1 0 0 1 1 1 1 Nuclear envelope localisation domain Flavi_NS4A PF01350.12 EME28161.1 - 0.028 13.9 0.1 0.13 11.8 0.1 1.9 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A TFIIB PF00382.14 EME28161.1 - 0.13 12.0 3.7 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Auto_anti-p27 PF06677.7 EME28161.1 - 7.8 6.3 6.7 8.3 6.2 3.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sigma70_r3 PF04539.11 EME28162.1 - 2.5e-20 72.1 2.8 1.6e-16 59.9 0.1 3.2 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r2 PF04542.9 EME28162.1 - 5.8e-19 67.4 0.2 1.6e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EME28162.1 - 4.9e-17 60.9 1.5 4.9e-17 60.9 1.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.15 EME28162.1 - 0.00025 20.6 0.1 0.00061 19.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 WD40 PF00400.27 EME28163.1 - 1.4e-31 107.1 0.6 1.1e-08 34.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EME28163.1 - 1.1e-11 44.4 12.5 2.8e-11 43.2 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME28163.1 - 2.6e-10 39.9 10.9 9.7e-10 38.1 7.6 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME28163.1 - 7.4e-10 38.3 13.3 2e-09 36.9 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME28163.1 - 1.6e-08 34.0 7.6 3.8e-08 32.8 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28163.1 - 6.6e-07 28.9 11.2 6.6e-07 28.9 7.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME28163.1 - 5.6e-05 22.7 7.9 0.00018 21.1 5.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EME28163.1 - 0.00018 21.2 2.0 0.00039 20.1 1.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EME28163.1 - 0.00055 19.7 12.7 0.0019 18.0 8.8 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EME28163.1 - 0.00098 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EME28163.1 - 0.0029 17.6 6.8 0.0029 17.6 4.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger BBS2_Mid PF14783.1 EME28163.1 - 0.0074 16.0 0.4 3 7.6 0.0 3.8 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region zf-RING_4 PF14570.1 EME28163.1 - 0.079 12.5 8.6 0.18 11.3 5.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EME28163.1 - 0.16 11.8 6.1 0.38 10.6 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.2 EME28163.1 - 0.23 11.3 7.0 0.73 9.7 4.8 1.9 1 0 0 1 1 1 0 Double zinc ribbon DUF342 PF03961.8 EME28163.1 - 0.52 8.6 3.5 0.77 8.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF445 PF04286.7 EME28163.1 - 0.82 9.1 6.9 1.3 8.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF410 PF04190.8 EME28164.1 - 3.7e-11 43.0 5.3 5.1e-11 42.6 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_15 PF13429.1 EME28164.1 - 0.0019 17.3 0.7 0.0077 15.3 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat XPG_I PF00867.13 EME28164.1 - 0.062 13.3 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 XPG I-region CLTH PF10607.4 EME28164.1 - 0.96 9.1 5.8 5.8 6.5 4.0 2.1 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TPR_2 PF07719.12 EME28164.1 - 3.8 7.6 5.5 67 3.7 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SATase_N PF06426.9 EME28165.1 - 1.3e-31 108.9 0.4 1.9e-31 108.4 0.3 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.19 EME28165.1 - 4.4e-11 41.7 8.1 5e-07 28.9 0.3 3.4 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME28165.1 - 0.1 12.1 9.2 0.31 10.6 1.4 2.6 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase NUC173 PF08161.7 EME28166.1 - 3.4e-16 59.1 3.8 4.8e-16 58.7 0.9 2.7 2 0 0 2 2 2 1 NUC173 domain GCFC PF07842.7 EME28167.1 - 7.4e-37 127.1 4.5 1.5e-36 126.1 3.1 1.6 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EME28167.1 - 1.6e-06 27.7 0.2 3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EME28167.1 - 0.0014 18.4 0.5 0.0052 16.5 0.4 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF1722 PF08349.6 EME28167.1 - 0.018 14.9 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) PfkB PF00294.19 EME28168.1 - 2.5e-26 92.5 0.0 3.2e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TRAPPC9-Trs120 PF08626.6 EME28169.1 - 8.7e-19 66.4 9.6 1.1e-10 39.6 1.2 4.9 4 1 0 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Pkinase PF00069.20 EME28170.1 - 1.6e-73 247.0 0.0 1.6e-73 247.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28170.1 - 1.5e-40 138.9 0.0 2.6e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EME28170.1 - 7.1e-31 105.9 0.8 4.8e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 EME28170.1 - 1.7e-07 30.4 1.1 1.5e-05 24.1 0.0 3.0 2 1 1 3 3 3 1 Kinase-like DUF4524 PF15025.1 EME28170.1 - 0.0067 15.9 0.0 0.32 10.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) R3H-assoc PF13902.1 EME28170.1 - 0.083 12.8 6.2 0.2 11.5 0.9 3.7 3 1 0 4 4 4 0 R3H-associated N-terminal domain DUF892 PF05974.7 EME28170.1 - 0.17 11.6 8.6 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF2458 PF10454.4 EME28170.1 - 8.4 6.2 14.9 0.43 10.4 3.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) PUF PF00806.14 EME28171.1 - 3e-59 193.3 6.4 1.5e-07 30.4 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HNOB PF07700.10 EME28171.1 - 0.12 11.9 1.5 14 5.1 0.0 3.7 4 0 0 4 4 4 0 Heme NO binding SapB_2 PF03489.12 EME28171.1 - 0.62 10.1 2.4 5.7 7.0 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 AAA_27 PF13514.1 EME28172.1 - 0.00041 18.2 13.0 0.00053 17.8 9.0 1.0 1 0 0 1 1 1 1 AAA domain Mnd1 PF03962.10 EME28172.1 - 0.0049 16.5 16.2 0.0078 15.8 11.2 1.3 1 0 0 1 1 1 1 Mnd1 family AAA_13 PF13166.1 EME28172.1 - 0.0063 15.0 13.2 0.008 14.6 9.1 1.1 1 0 0 1 1 1 1 AAA domain DUF2009 PF09418.5 EME28172.1 - 0.0077 15.0 3.2 0.011 14.5 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Spc7 PF08317.6 EME28172.1 - 0.013 14.2 17.1 0.017 13.8 11.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EME28172.1 - 0.018 14.0 16.7 0.025 13.5 11.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_3 PF13758.1 EME28172.1 - 0.036 13.8 16.4 0.061 13.0 11.4 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF342 PF03961.8 EME28172.1 - 0.044 12.1 13.1 0.063 11.6 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2193 PF09959.4 EME28172.1 - 0.098 10.8 1.4 0.13 10.4 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Orbi_VP5 PF00901.12 EME28172.1 - 0.23 9.6 11.8 0.31 9.1 8.2 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 HAUS6_N PF14661.1 EME28172.1 - 0.3 10.4 15.2 0.64 9.3 10.5 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF641 PF04859.7 EME28172.1 - 0.61 9.8 15.9 0.97 9.1 11.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HSBP1 PF06825.7 EME28172.1 - 0.93 9.1 13.9 0.33 10.5 4.8 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 zf-C4H2 PF10146.4 EME28172.1 - 1 9.3 15.2 1.4 8.8 10.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_S46 PF10459.4 EME28172.1 - 1.5 7.1 9.0 1.9 6.7 6.3 1.1 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.10 EME28172.1 - 2.1 7.4 11.0 2.7 7.0 7.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.7 EME28172.1 - 2.7 8.3 7.3 4.4 7.6 4.2 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DNA_topoisoIV PF00521.15 EME28172.1 - 2.7 6.7 11.6 3.9 6.2 8.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Vfa1 PF08432.5 EME28172.1 - 4.2 7.3 15.2 6 6.8 10.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HSP70 PF00012.15 EME28172.1 - 5.1 4.8 13.2 6.6 4.5 9.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Phage_GPO PF05929.6 EME28172.1 - 6.2 5.9 11.2 8.8 5.4 7.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6 PF04111.7 EME28172.1 - 6.9 5.6 30.6 2.8 6.9 13.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EME28172.1 - 7 6.7 24.9 38 4.3 16.4 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Borrelia_P83 PF05262.6 EME28172.1 - 7.9 4.6 16.7 11 4.1 11.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.4 EME28172.1 - 8.3 4.5 18.8 13 3.9 13.0 1.2 1 0 0 1 1 1 0 Transmembrane protein BLOC1_2 PF10046.4 EME28172.1 - 9.2 6.4 18.0 1.7e+02 2.4 12.5 2.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-RING_2 PF13639.1 EME28173.1 - 3.4e-09 36.4 19.8 7.8e-09 35.2 13.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME28173.1 - 0.0025 17.9 13.5 0.015 15.4 8.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME28173.1 - 0.021 14.4 15.9 0.044 13.4 11.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP1G1_PLM_MAT8 PF02038.11 EME28173.1 - 0.041 12.9 0.1 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-C3HC4 PF00097.20 EME28173.1 - 0.14 11.8 19.4 0.32 10.6 13.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28173.1 - 0.67 10.0 21.6 1.4 8.9 15.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28173.1 - 1.5 8.5 16.7 3.6 7.4 11.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RabGAP-TBC PF00566.13 EME28174.1 - 2.4e-42 144.8 11.0 2.4e-42 144.8 7.6 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Coq4 PF05019.8 EME28175.1 - 1e-29 103.0 0.0 1.3e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 OMPdecase PF00215.19 EME28177.1 - 6.2e-70 235.1 0.0 8.8e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 EME28177.1 - 2.2e-08 33.8 0.0 8.8e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HTH_DeoR PF08220.7 EME28177.1 - 0.049 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain OMPdecase PF00215.19 EME28178.1 - 4.6e-67 225.7 0.0 6.6e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 EME28178.1 - 2.3e-08 33.7 0.0 9.2e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HTH_DeoR PF08220.7 EME28178.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Sugar_tr PF00083.19 EME28179.1 - 7.1e-91 305.0 35.3 8.5e-91 304.7 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28179.1 - 3.8e-22 78.4 23.7 3.8e-22 78.4 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.3 EME28179.1 - 0.41 10.5 0.0 0.41 10.5 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) bZIP_Maf PF03131.12 EME28180.1 - 8.4e-07 29.2 4.1 1.2e-06 28.7 2.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EME28180.1 - 2.3e-06 27.4 14.2 5.2e-06 26.3 9.9 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME28180.1 - 5.1e-06 26.2 12.5 8.6e-06 25.4 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper CCDC155 PF14662.1 EME28180.1 - 0.023 14.3 1.7 0.072 12.6 0.4 1.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Cep57_CLD_2 PF14197.1 EME28180.1 - 0.1 12.5 5.8 0.19 11.7 4.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 EME28180.1 - 2.7 7.7 5.2 1.5 8.6 1.0 2.4 2 1 1 3 3 3 0 Homeobox associated leucine zipper UFD1 PF03152.9 EME28181.1 - 1.7e-73 245.4 0.0 2.5e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RNA_pol_A_bac PF01000.21 EME28182.1 - 5.9e-31 106.9 0.0 1.1e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EME28182.1 - 4.1e-07 29.0 0.0 5.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 EME28182.1 - 0.025 14.9 0.6 0.051 13.9 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain NDK PF00334.14 EME28183.1 - 2.8e-53 179.3 0.0 5e-53 178.5 0.0 1.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase FBP PF07299.6 EME28183.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Metallophos PF00149.23 EME28184.1 - 2.2e-07 30.4 0.2 1e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EME28184.1 - 0.00029 19.5 0.6 0.0014 17.3 0.3 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EME28184.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aconitase_C PF00694.14 EME28185.1 - 1.7e-18 66.9 0.2 6.2e-18 65.1 0.1 2.0 2 1 0 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EME28185.1 - 0.065 12.6 0.0 1.1 8.6 0.0 2.2 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus GerA PF03323.8 EME28185.1 - 0.12 10.4 0.1 0.26 9.3 0.0 1.5 1 1 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein PMSR PF01625.16 EME28186.1 - 2.6e-63 212.5 2.5 3.4e-63 212.2 1.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase 2-Hacid_dh_C PF02826.14 EME28187.1 - 5.7e-53 178.6 0.0 8.9e-53 178.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME28187.1 - 2.1e-28 98.4 0.0 2.6e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME28187.1 - 0.0005 19.9 0.0 0.0029 17.4 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EME28187.1 - 0.00088 18.6 0.0 0.068 12.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_N PF05222.10 EME28187.1 - 0.11 12.5 0.0 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain Mak10 PF04112.8 EME28188.1 - 4.7e-16 58.4 2.2 3.3e-15 55.7 1.5 2.2 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Peroxin-22 PF12827.2 EME28189.1 - 0.00099 18.8 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family DUF1469 PF07332.6 EME28189.1 - 0.058 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Exo_endo_phos PF03372.18 EME28190.1 - 1.4e-13 51.3 0.1 1.8e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Bac_surface_Ag PF01103.18 EME28191.1 - 1.3e-37 130.0 2.5 1.6e-37 129.7 1.8 1.1 1 0 0 1 1 1 1 Surface antigen IL4 PF00727.13 EME28192.1 - 0.1 12.5 0.3 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Interleukin 4 ABC_tran PF00005.22 EME28193.1 - 1.2e-14 54.7 0.0 4.1e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME28193.1 - 1.2e-06 28.7 0.2 0.0074 16.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EME28193.1 - 6.7e-05 22.2 0.1 0.028 13.6 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MutS_V PF00488.16 EME28193.1 - 0.00076 18.9 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain V AAA_25 PF13481.1 EME28193.1 - 0.0049 16.2 0.1 0.015 14.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28193.1 - 0.0051 16.8 0.1 0.0059 16.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME28193.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EME28193.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME28193.1 - 0.049 13.5 0.0 0.067 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME28193.1 - 0.073 13.2 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME28193.1 - 0.11 11.9 0.0 9.7 5.5 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EME28193.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EME28194.1 - 6.2e-10 38.8 0.0 1.3e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EME28194.1 - 4.6e-06 25.9 0.0 0.069 12.2 0.0 2.3 2 0 0 2 2 2 2 ATPase MipZ DUF1505 PF07403.6 EME28195.1 - 0.59 10.0 9.1 0.073 13.0 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) IBN_N PF03810.14 EME28196.1 - 1.8e-14 53.3 1.1 8.4e-12 44.8 0.2 3.6 4 0 0 4 4 4 2 Importin-beta N-terminal domain HEAT PF02985.17 EME28196.1 - 1e-12 47.0 11.0 0.0018 18.1 0.1 8.8 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 EME28196.1 - 3.8e-12 46.3 9.2 5.8e-06 26.4 0.0 6.8 2 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EME28196.1 - 9.3e-12 45.0 10.1 2.6e-09 37.2 0.1 6.6 7 1 1 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME28196.1 - 0.00054 20.2 3.8 0.24 11.7 0.7 5.0 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EME28196.1 - 0.00057 19.6 8.1 0.017 14.9 0.1 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Fasciclin PF02469.17 EME28197.1 - 0.00029 20.8 0.3 0.00045 20.2 0.2 1.3 1 0 0 1 1 1 1 Fasciclin domain UPF0118 PF01594.11 EME28197.1 - 0.17 10.8 4.0 0.24 10.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 Agouti PF05039.7 EME28198.1 - 5.3 7.4 12.6 1.2 9.5 6.4 1.7 1 1 0 1 1 1 0 Agouti protein BSD PF03909.12 EME28199.1 - 4e-15 55.3 0.2 1.8e-10 40.4 0.0 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EME28199.1 - 6.6e-09 35.2 0.2 1.6e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EME28200.1 - 3.8e-15 55.3 0.1 1.8e-10 40.4 0.0 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EME28200.1 - 6.8e-09 35.2 0.2 1.7e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain GRASP55_65 PF04495.9 EME28201.1 - 3.8e-08 33.4 0.0 4.3e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EME28201.1 - 8.2e-05 22.4 0.0 8.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EME28201.1 - 0.019 14.7 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.9 EME28202.1 - 5e-38 130.2 0.1 8.1e-29 100.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EME28202.1 - 1.7e-06 27.7 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.1 EME28202.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RRM_1 PF00076.17 EME28204.1 - 1.3e-13 50.4 0.5 3.6e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28204.1 - 1.6e-09 37.6 0.0 1.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EME28204.1 - 7.2e-05 22.6 18.6 0.0076 16.0 0.5 3.7 2 2 1 3 3 3 3 Suppressor of forked protein (Suf) U3_assoc_6 PF08640.6 EME28204.1 - 0.0026 17.4 0.5 0.96 9.2 0.0 3.1 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EME28204.1 - 0.11 13.1 0.3 1 10.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF563 PF04577.9 EME28205.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF563) T2SG PF08334.6 EME28205.1 - 0.057 13.1 0.1 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G DUF4372 PF14294.1 EME28205.1 - 0.28 11.1 2.1 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4372) RecA PF00154.16 EME28206.1 - 1.4e-147 491.0 0.6 1.6e-147 490.7 0.4 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EME28206.1 - 5e-08 32.3 1.5 5.6e-06 25.6 1.0 2.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 EME28206.1 - 7.3e-07 28.7 2.3 3.4e-05 23.3 1.6 2.2 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EME28206.1 - 8.2e-07 28.1 0.2 1.8e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 Rad51 AAA PF00004.24 EME28206.1 - 0.001 19.2 0.0 0.0059 16.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EME28206.1 - 0.0044 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EME28206.1 - 0.0082 16.1 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EME28206.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EME28206.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TPT PF03151.11 EME28207.1 - 4.9e-30 104.2 11.9 4.9e-30 104.2 8.3 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME28207.1 - 0.00018 21.5 33.7 0.0023 17.9 12.3 3.1 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EME28207.1 - 0.0062 15.4 28.4 0.015 14.1 19.7 1.6 1 1 0 1 1 1 1 UAA transporter family GET2 PF08690.5 EME28207.1 - 0.52 9.5 2.7 0.95 8.6 1.9 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Acetyltransf_1 PF00583.19 EME28208.1 - 4.2e-16 58.7 0.0 5.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME28208.1 - 4.1e-11 42.8 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME28208.1 - 1.2e-05 25.0 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EME28208.1 - 5.1e-05 23.3 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME28208.1 - 0.00016 21.4 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME28208.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Methyltransf_2 PF00891.13 EME28209.1 - 1.4e-39 135.7 0.0 1.7e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EME28209.1 - 0.022 15.3 0.0 0.027 15.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EME28209.1 - 0.043 14.2 0.0 0.49 10.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EME28209.1 - 0.085 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME28209.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Lipid_DES PF08557.5 EME28209.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Methyltransf_2 PF00891.13 EME28210.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PIP49_C PF12260.3 EME28212.1 - 0.061 12.7 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 UL73_N PF12522.3 EME28212.1 - 4.4 6.9 5.5 9.4 5.8 0.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal ChAPs PF09295.5 EME28213.1 - 1.2e-13 50.5 0.0 1.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EME28213.1 - 0.001 18.6 0.1 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EME28213.1 - 0.0013 19.2 0.2 0.65 10.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME28213.1 - 0.0013 18.4 0.5 4.4 7.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME28213.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME28213.1 - 0.0048 17.1 0.1 0.014 15.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME28213.1 - 0.016 15.8 0.1 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME28213.1 - 0.049 13.4 0.1 0.91 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME28213.1 - 0.062 12.9 0.0 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME28214.1 - 1.3e-05 25.7 3.1 3.3e-05 24.4 0.2 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME28214.1 - 0.0001 21.9 4.4 0.024 14.5 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME28214.1 - 0.00011 21.7 0.9 0.001 18.6 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 EME28214.1 - 0.00066 19.9 1.5 1.6 9.1 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME28214.1 - 0.0079 15.7 3.8 0.41 10.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME28214.1 - 0.02 15.4 2.7 3.6 8.4 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME28214.1 - 0.045 13.5 1.1 21 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EME28214.1 - 0.29 11.2 1.4 11 6.2 0.1 3.7 4 0 0 4 4 4 0 PPR repeat SmpB PF01668.13 EME28215.1 - 1.6e-24 85.4 0.0 2.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 SmpB protein peroxidase PF00141.18 EME28216.1 - 1.2e-49 168.9 0.0 2e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase zf-primase PF09329.6 EME28218.1 - 8.4e-10 38.1 3.7 2.7e-09 36.4 1.6 2.5 2 0 0 2 2 2 1 Primase zinc finger zf-primase PF09329.6 EME28219.1 - 8.6e-10 38.0 3.7 2.8e-09 36.4 1.6 2.5 2 0 0 2 2 2 1 Primase zinc finger DUF21 PF01595.15 EME28220.1 - 1.6e-25 89.4 3.1 2.5e-25 88.8 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME28220.1 - 1.5e-09 37.4 0.4 0.0003 20.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain UEV PF05743.8 EME28221.1 - 5.5e-23 80.9 1.4 1.5e-22 79.5 0.8 1.8 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 EME28221.1 - 2.1e-11 43.2 0.7 2.1e-11 43.2 0.5 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 EME28221.1 - 9.7e-06 25.0 0.4 9.7e-06 25.0 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Ppx-GppA PF02541.11 EME28221.1 - 0.0055 15.9 2.7 0.0086 15.2 1.9 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Erythro_esteras PF05139.9 EME28221.1 - 0.16 11.1 3.0 0.24 10.5 2.1 1.3 1 0 0 1 1 1 0 Erythromycin esterase Cnl2_NKP2 PF09447.5 EME28221.1 - 0.39 10.4 5.3 0.5 10.0 0.3 3.1 3 0 0 3 3 3 0 Cnl2/NKP2 family protein DUF3829 PF12889.2 EME28221.1 - 1.3 8.1 10.0 0.62 9.2 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) FabA PF07977.8 EME28222.1 - 1.5e-35 121.6 0.0 2e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.14 EME28222.1 - 0.0009 18.6 0.0 0.0016 17.7 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain FabA PF07977.8 EME28223.1 - 3.6e-34 117.2 0.0 4.8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.14 EME28223.1 - 0.0013 18.0 0.1 0.0028 17.0 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain DUF89 PF01937.14 EME28224.1 - 0.0079 15.0 0.4 0.01 14.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF89 NCD3G PF07562.9 EME28224.1 - 0.0081 15.8 1.5 0.02 14.6 1.1 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Glycos_transf_1 PF00534.15 EME28225.1 - 1.4e-22 79.9 0.1 2.4e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME28225.1 - 2.3e-10 40.7 0.0 9.3e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME28225.1 - 0.0002 21.5 0.1 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 MscS_TM PF12794.2 EME28225.1 - 0.023 13.3 0.1 0.043 12.4 0.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Glyco_transf_4 PF13439.1 EME28225.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RVT_thumb PF06817.9 EME28225.1 - 0.095 12.2 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Adeno_E3_14_5 PF04834.7 EME28226.1 - 0.068 13.5 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Early E3 14.5 kDa protein PsbN PF02468.10 EME28226.1 - 0.7 9.5 2.8 0.66 9.6 0.9 1.6 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) rRNA_methylase PF06962.7 EME28227.1 - 1.2e-33 115.8 0.0 1.6e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Putative rRNA methylase Ubie_methyltran PF01209.13 EME28227.1 - 0.00014 21.1 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EME28227.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28227.1 - 0.0016 18.5 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 EME28228.1 - 2.5e-64 218.0 10.2 3.9e-53 181.2 2.0 2.0 1 1 1 2 2 2 2 Vta1 like DUF4602 PF15375.1 EME28229.1 - 4.5e-07 30.0 5.3 6.6e-07 29.4 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) DUF3023 PF11224.3 EME28229.1 - 0.028 14.0 1.7 0.045 13.4 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3023) DUF3175 PF11373.3 EME28229.1 - 0.29 11.1 4.1 0.27 11.2 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3175) E1_dh PF00676.15 EME28230.1 - 2.3e-85 285.9 0.0 3.1e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 EME28230.1 - 0.00064 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 EME28230.1 - 0.00065 18.7 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase SAP18 PF06487.7 EME28230.1 - 0.042 13.6 0.1 1.4 8.7 0.0 3.0 1 1 1 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) TPP_enzyme_C PF02775.16 EME28230.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DEAD PF00270.24 EME28233.1 - 5.6e-47 159.3 0.0 2.1e-45 154.2 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28233.1 - 1.6e-25 88.7 1.8 2.8e-25 87.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME28233.1 - 8e-05 21.5 0.0 0.00016 20.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Phi-29_GP16_7 PF06720.6 EME28233.1 - 0.14 11.7 5.1 0.13 11.9 2.0 2.1 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 DUF3619 PF12279.3 EME28233.1 - 0.21 11.6 3.8 0.57 10.2 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Pkinase PF00069.20 EME28234.1 - 1.7e-73 246.9 0.0 2e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28234.1 - 1.1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME28234.1 - 5.1e-08 32.2 0.1 0.0003 19.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EME28234.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EME28234.1 - 0.018 13.8 0.1 0.045 12.5 0.0 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EME28234.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SpoIIE PF07228.7 EME28235.1 - 1.1e-09 38.2 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EME28235.1 - 1.4e-05 24.6 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EME28235.1 - 0.0032 16.9 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME28236.1 - 1.7e-09 37.6 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EME28236.1 - 6.6e-05 22.4 0.1 0.06 12.7 0.0 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EME28236.1 - 0.0032 16.9 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CBM_20 PF00686.14 EME28237.1 - 5.9e-13 48.2 0.0 7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Starch binding domain Aminotran_3 PF00202.16 EME28238.1 - 1.5e-42 145.6 0.0 1.2e-41 142.7 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-III AAA_26 PF13500.1 EME28238.1 - 6.5e-35 120.5 0.0 1.6e-34 119.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EME28238.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MRP-L20 PF12824.2 EME28239.1 - 8.1e-07 29.1 0.3 8.1e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 MRP-S22 PF10245.4 EME28239.1 - 9.7e-05 21.8 0.1 0.00035 20.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S22 HTH_11 PF08279.7 EME28239.1 - 0.0045 16.5 0.2 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.1 EME28239.1 - 0.012 15.2 0.0 0.053 13.1 0.0 2.2 1 0 0 1 1 1 0 Homeodomain-like domain Cytokin_check_N PF10407.4 EME28239.1 - 0.1 12.2 0.1 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Methyltrn_RNA_3 PF02598.12 EME28240.1 - 5.8e-64 216.2 0.0 7.1e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Cyclase PF04199.8 EME28241.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase ADH_zinc_N PF00107.21 EME28242.1 - 4.9e-25 87.5 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME28242.1 - 7.6e-25 86.7 0.9 7.6e-25 86.7 0.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.16 EME28242.1 - 0.0068 16.2 0.4 0.011 15.5 0.3 1.4 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EME28242.1 - 0.06 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ufd2P_core PF10408.4 EME28243.1 - 1.2e-170 568.9 3.5 2.1e-170 568.0 2.4 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EME28243.1 - 1.6e-25 88.8 0.7 5.7e-25 87.0 0.5 2.0 1 0 0 1 1 1 1 U-box domain DUF3593 PF12159.3 EME28244.1 - 3.6e-27 93.9 2.4 5.4e-27 93.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) zf-LITAF-like PF10601.4 EME28244.1 - 0.0027 17.5 0.6 0.0027 17.5 0.4 3.0 4 0 0 4 4 4 1 LITAF-like zinc ribbon domain OppC_N PF12911.2 EME28244.1 - 0.0045 16.3 0.1 0.028 13.8 0.1 2.1 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Colicin_V PF02674.11 EME28244.1 - 0.014 15.1 1.4 0.023 14.5 1.0 1.3 1 0 0 1 1 1 0 Colicin V production protein DsbD_2 PF13386.1 EME28244.1 - 0.2 11.4 3.5 3.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF3593 PF12159.3 EME28245.1 - 1.5e-22 79.1 6.0 7.8e-22 76.8 4.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3593) zf-LITAF-like PF10601.4 EME28245.1 - 0.0032 17.2 0.6 0.0032 17.2 0.4 2.9 4 0 0 4 4 4 1 LITAF-like zinc ribbon domain OppC_N PF12911.2 EME28245.1 - 0.0059 15.9 0.1 0.032 13.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Colicin_V PF02674.11 EME28245.1 - 0.038 13.8 1.9 0.058 13.2 1.3 1.4 1 1 0 1 1 1 0 Colicin V production protein DsbD_2 PF13386.1 EME28245.1 - 0.4 10.4 4.0 6.7 6.4 0.0 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region CRAL_TRIO PF00650.15 EME28246.1 - 4.4e-28 97.7 0.2 6.1e-28 97.3 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME28246.1 - 2.5e-08 33.9 0.1 1e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EME28246.1 - 7.3e-06 25.9 0.8 1.5e-05 24.9 0.6 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Fib_alpha PF08702.5 EME28246.1 - 0.0077 16.3 0.4 0.018 15.1 0.1 1.8 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF310 PF03750.8 EME28246.1 - 0.083 13.0 0.2 0.27 11.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Thioredoxin_9 PF14595.1 EME28246.1 - 0.18 11.3 0.7 1.1 8.7 0.0 2.5 2 1 1 3 3 3 0 Thioredoxin CRAL_TRIO PF00650.15 EME28247.1 - 2e-38 131.4 0.8 2.6e-38 131.0 0.6 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME28247.1 - 2.3e-08 34.0 0.1 1.1e-07 31.8 0.0 2.3 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EME28247.1 - 2.7e-07 30.6 0.8 5.2e-07 29.6 0.5 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Fib_alpha PF08702.5 EME28247.1 - 0.009 16.1 0.4 0.021 14.9 0.1 1.7 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DPM2 PF07297.7 EME28247.1 - 0.061 13.6 0.1 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF310 PF03750.8 EME28247.1 - 0.082 13.1 0.9 0.23 11.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF310) Thioredoxin_9 PF14595.1 EME28247.1 - 0.19 11.3 2.6 1.2 8.7 0.0 3.1 3 1 1 4 4 4 0 Thioredoxin DEAD PF00270.24 EME28248.1 - 3.3e-48 163.3 0.1 6e-48 162.5 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28248.1 - 4e-26 90.6 0.3 3.8e-25 87.5 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME28248.1 - 0.00046 20.0 0.1 0.0015 18.3 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME28248.1 - 0.029 14.4 0.1 0.88 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain MIR PF02815.14 EME28249.1 - 2.3e-15 56.6 1.8 3.5e-13 49.5 0.0 2.6 1 1 1 2 2 2 2 MIR domain DAGK_acc PF00609.14 EME28250.1 - 8.9e-34 116.9 0.0 1.7e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EME28250.1 - 4.2e-17 61.8 0.0 1.8e-14 53.2 0.0 2.3 1 1 1 2 2 2 2 Diacylglycerol kinase catalytic domain PGM_PMM_I PF02878.11 EME28251.1 - 2.8e-16 59.2 0.0 6.2e-08 32.2 0.0 2.7 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EME28251.1 - 7.9e-09 35.7 0.0 3.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EME28251.1 - 7.7e-07 29.0 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4228 PF14009.1 EME28251.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RabGAP-TBC PF00566.13 EME28252.1 - 2.1e-48 164.6 0.3 9.3e-48 162.5 0.2 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_C37 PF05416.7 EME28253.1 - 0.031 12.5 6.3 0.04 12.2 4.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Nucleoplasmin PF03066.10 EME28253.1 - 0.037 13.5 5.5 0.054 13.0 3.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop53 PF07767.6 EME28253.1 - 0.11 11.4 18.7 0.13 11.1 12.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 EME28253.1 - 0.25 9.6 21.5 0.32 9.3 14.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BioY PF02632.9 EME28253.1 - 0.3 10.7 5.6 0.081 12.5 0.8 2.2 2 1 0 2 2 2 0 BioY family Peptidase_S49_N PF08496.5 EME28253.1 - 0.31 10.8 4.4 0.48 10.2 3.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2201_N PF13203.1 EME28253.1 - 0.38 9.8 3.7 0.51 9.4 2.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain YqfQ PF14181.1 EME28253.1 - 0.45 10.5 12.6 0.62 10.0 8.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 EME28253.1 - 1.2 7.0 16.1 1.6 6.6 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EME28253.1 - 1.3 6.7 7.8 1.7 6.4 5.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.8 EME28253.1 - 2.3 6.8 15.0 2.9 6.5 10.4 1.1 1 0 0 1 1 1 0 Paf1 Med19 PF10278.4 EME28253.1 - 4.3 6.9 16.1 5.4 6.6 11.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.12 EME28253.1 - 4.9 6.8 8.7 6.9 6.3 6.0 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 EME28253.1 - 5.3 4.8 18.5 6.8 4.4 12.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3408 PF11888.3 EME28253.1 - 6.8 6.6 12.2 10 6.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF1510 PF07423.6 EME28253.1 - 8.9 5.6 17.4 13 5.1 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vpu PF00558.14 EME28253.1 - 9.9 5.7 6.8 0.5 9.9 0.4 2.1 2 0 0 2 2 2 0 Vpu protein CPSase_L_D2 PF02786.12 EME28254.1 - 7.7e-114 378.2 0.0 2.1e-81 272.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EME28254.1 - 7.8e-47 158.0 0.0 1.9e-46 156.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EME28254.1 - 7.3e-45 152.1 0.0 1.5e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EME28254.1 - 7e-41 139.7 0.0 1.5e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_chain PF00289.17 EME28254.1 - 2.9e-40 136.8 0.1 3.6e-19 68.8 0.0 3.6 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 EME28254.1 - 3.5e-40 137.5 0.0 7.8e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EME28254.1 - 1.1e-39 135.0 0.2 3.5e-39 133.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EME28254.1 - 1.7e-34 119.1 0.1 3.4e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EME28254.1 - 1.3e-20 73.1 0.0 1.5e-18 66.5 0.0 3.8 4 0 0 4 4 3 1 MGS-like domain OGG_N PF07934.7 EME28254.1 - 1.4e-19 70.1 0.0 3.7e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain Dala_Dala_lig_C PF07478.8 EME28254.1 - 2.7e-17 62.8 0.2 6e-09 35.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EME28254.1 - 6.3e-17 61.4 0.0 2.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME28254.1 - 8.1e-17 60.9 0.1 1.4e-10 40.4 0.1 3.5 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EME28254.1 - 6.4e-08 32.6 0.1 0.00026 20.9 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EME28254.1 - 3.9e-07 29.7 0.0 1.5e-05 24.5 0.1 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 EME28254.1 - 0.0009 18.7 0.1 0.016 14.6 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 HHH PF00633.18 EME28254.1 - 0.076 12.7 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF962 PF06127.6 EME28255.1 - 0.036 13.9 1.2 0.18 11.6 0.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF962) zf-C3HC4_3 PF13920.1 EME28256.1 - 0.021 14.5 11.3 0.036 13.7 7.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME28256.1 - 7.3 6.3 15.3 15 5.3 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DP PF08781.5 EME28257.1 - 8.3e-22 77.4 0.7 2.1e-21 76.1 0.5 1.6 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 EME28257.1 - 3.1e-11 42.6 0.0 9.3e-11 41.1 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain EXOSC1 PF10447.4 EME28258.1 - 4e-19 68.3 0.3 5.9e-19 67.8 0.2 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EME28258.1 - 3e-05 23.2 0.0 8e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Spt20 PF12090.3 EME28259.1 - 6.3e-16 58.2 0.1 1.1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Spt20 family Sugar_tr PF00083.19 EME28260.1 - 1.2e-83 281.1 17.0 1.6e-83 280.8 11.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28260.1 - 5.4e-25 87.8 19.4 5.4e-25 87.8 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EME28260.1 - 0.00067 19.7 3.5 11 6.1 1.1 3.9 3 0 0 3 3 3 3 Phage holin family 2 TPR_1 PF00515.23 EME28261.1 - 1.1e-34 116.5 11.4 2.5e-06 26.8 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EME28261.1 - 1.2e-32 109.1 19.4 1.7e-05 24.3 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EME28261.1 - 1.2e-31 108.1 17.8 4e-10 39.2 0.4 5.8 3 1 3 6 6 6 5 TPR repeat APC8 PF04049.8 EME28261.1 - 8e-29 100.1 3.9 8e-29 100.1 2.7 2.8 2 1 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 EME28261.1 - 1.8e-22 77.3 16.5 8.8e-06 25.1 0.0 7.7 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME28261.1 - 4.4e-21 74.5 18.7 1.7e-07 31.0 0.2 6.9 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME28261.1 - 5.4e-19 66.9 4.1 0.00023 21.5 0.0 8.0 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 EME28261.1 - 8.7e-19 66.0 6.3 0.0035 17.4 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EME28261.1 - 9.6e-19 67.5 6.9 1.2e-05 25.8 0.1 6.3 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EME28261.1 - 1.6e-16 58.7 17.5 0.069 12.9 0.1 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME28261.1 - 6.8e-12 45.5 1.7 0.035 14.4 0.0 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 EME28261.1 - 3.5e-10 39.3 3.0 0.00068 18.7 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME28261.1 - 4.3e-10 39.3 22.4 0.57 10.7 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EME28261.1 - 4.3e-09 36.3 20.4 8.2e-05 22.6 0.4 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EME28261.1 - 2.7e-08 33.5 4.7 0.022 14.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME28261.1 - 7.4e-07 28.8 15.3 0.063 13.2 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat ChAPs PF09295.5 EME28261.1 - 0.0003 19.6 0.2 0.01 14.6 0.0 3.0 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 EME28261.1 - 0.0039 17.0 1.3 3.4 7.6 0.0 4.3 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EME28261.1 - 0.0088 16.6 10.0 18 6.1 0.0 5.6 6 0 0 6 6 5 0 Sel1 repeat ATP-synt_F PF01990.12 EME28262.1 - 8.3e-29 99.8 0.1 9.7e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ENTH PF01417.15 EME28264.1 - 4.1e-34 117.1 0.7 3.4e-33 114.1 0.0 2.4 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 EME28264.1 - 0.00041 19.1 0.3 0.00074 18.3 0.2 1.4 1 0 0 1 1 1 1 ANTH domain DUF1982 PF09326.6 EME28264.1 - 0.0011 19.0 0.0 0.0047 17.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) APS_kinase PF01583.15 EME28265.1 - 3.4e-36 124.2 0.0 3.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EME28265.1 - 1.4e-05 25.0 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME28265.1 - 9.6e-05 21.7 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EME28265.1 - 0.00011 22.5 0.2 0.0002 21.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME28265.1 - 0.00011 23.0 0.0 0.00013 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EME28265.1 - 0.0036 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EME28265.1 - 0.027 14.6 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EME28265.1 - 0.05 13.1 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EME28265.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP-grasp_5 PF13549.1 EME28266.1 - 2.2e-67 226.5 0.5 3.7e-67 225.8 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EME28266.1 - 2e-33 114.8 0.0 1.3e-27 96.0 0.0 3.1 3 0 0 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EME28266.1 - 7.6e-05 22.1 0.7 0.00022 20.6 0.5 1.9 1 1 0 1 1 1 1 ATP-grasp domain CoA_binding_2 PF13380.1 EME28266.1 - 0.00022 21.3 0.0 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_4 PF13535.1 EME28266.1 - 0.0006 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EME28266.1 - 0.031 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EME28266.1 - 0.039 13.4 0.1 0.078 12.4 0.1 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Mito_carr PF00153.22 EME28267.1 - 9.1e-23 79.7 3.9 5.4e-10 38.8 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein AAA_12 PF13087.1 EME28268.1 - 1.1e-27 96.7 0.0 2.5e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME28268.1 - 3.9e-16 59.3 0.0 7.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME28268.1 - 2.6e-10 39.8 0.0 2.5e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EME28268.1 - 2.1e-06 27.4 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME28268.1 - 0.0015 18.6 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28268.1 - 0.0073 16.3 0.0 0.026 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EME28268.1 - 0.029 13.3 0.0 0.31 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EME28268.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME28268.1 - 0.069 13.9 0.1 0.4 11.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME28268.1 - 0.07 12.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME28268.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP9-21 PF05486.7 EME28269.1 - 4.2e-15 55.2 0.1 4.8e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Sugar_tr PF00083.19 EME28270.1 - 1.6e-36 125.9 28.5 9.9e-35 119.9 19.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28270.1 - 8.3e-22 77.3 57.1 7.1e-16 57.8 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EME28270.1 - 0.0054 15.5 2.4 0.0056 15.4 0.3 1.6 1 1 0 1 1 1 1 BT1 family MMR_HSR1 PF01926.18 EME28271.1 - 1.5e-18 66.8 0.1 3.1e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME28271.1 - 1.1e-07 31.3 0.1 1.7e-06 27.3 0.0 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EME28271.1 - 2.3e-07 30.8 2.5 2.9e-05 23.9 0.1 3.0 2 1 2 4 4 4 2 Dynamin family AIG1 PF04548.11 EME28271.1 - 2.2e-06 26.9 0.3 4.8e-06 25.8 0.2 1.6 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EME28271.1 - 3.7e-06 26.5 0.1 0.00072 19.0 0.0 3.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EME28271.1 - 9.1e-06 26.1 0.6 6.2e-05 23.4 0.0 2.5 2 1 1 3 3 2 1 Miro-like protein DUF258 PF03193.11 EME28271.1 - 2.3e-05 23.6 0.0 5.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 KH_2 PF07650.12 EME28271.1 - 2.9e-05 23.5 0.0 8.4e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 KH domain Arf PF00025.16 EME28271.1 - 0.00028 20.1 1.1 0.0013 18.0 0.8 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_10 PF12846.2 EME28271.1 - 0.0014 18.1 0.5 0.61 9.4 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain Ras PF00071.17 EME28271.1 - 0.0016 17.8 1.3 0.19 11.1 0.0 2.7 3 0 0 3 3 3 1 Ras family GBP PF02263.14 EME28271.1 - 0.0039 16.2 0.4 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain SRPRB PF09439.5 EME28271.1 - 0.018 14.2 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EME28271.1 - 0.018 15.1 0.3 0.083 13.0 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EME28271.1 - 0.028 14.2 0.9 0.089 12.6 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME28271.1 - 0.082 12.8 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.24 EME28271.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 KH domain AAA_17 PF13207.1 EME28271.1 - 0.11 13.2 0.1 0.3 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME28271.1 - 0.32 11.2 2.2 0.65 10.2 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Peptidase_M50 PF02163.17 EME28272.1 - 2.2e-47 160.4 0.3 2.7e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.1 EME28272.1 - 7.7e-07 28.9 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EME28272.1 - 0.00032 20.8 0.1 0.0006 19.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_M50B PF13398.1 EME28272.1 - 0.0087 15.4 0.1 0.0087 15.4 0.0 2.2 3 0 0 3 3 3 1 Peptidase M50B-like Rad51 PF08423.6 EME28274.1 - 4.7e-139 461.5 0.2 5.9e-139 461.2 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EME28274.1 - 3.9e-14 52.5 0.0 5.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EME28274.1 - 1.6e-11 43.9 0.1 2.1e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EME28274.1 - 2.2e-10 40.5 0.1 6e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EME28274.1 - 3e-06 26.5 0.1 6.9e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EME28274.1 - 0.0039 17.3 0.0 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain HHH PF00633.18 EME28274.1 - 0.0068 16.0 0.1 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DnaB_C PF03796.10 EME28274.1 - 0.025 13.4 0.1 0.08 11.8 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EME28274.1 - 0.053 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein SpoOE-like PF09388.5 EME28274.1 - 0.055 12.9 0.0 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein G6PD_C PF02781.11 EME28275.1 - 2.6e-115 384.3 0.0 3.4e-115 383.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EME28275.1 - 3.1e-61 206.8 0.0 6.7e-61 205.7 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PUF PF00806.14 EME28276.1 - 8.4e-29 97.4 13.5 8e-06 25.0 0.1 9.0 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RICTOR_N PF14664.1 EME28276.1 - 0.036 12.6 1.2 0.045 12.3 0.1 1.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Lactamase_B_2 PF12706.2 EME28277.1 - 6.3e-11 42.1 0.4 6.3e-11 42.1 0.3 1.8 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME28277.1 - 5.8e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Cauli_AT PF03233.8 EME28277.1 - 0.052 13.2 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein UCH PF00443.24 EME28278.1 - 6.9e-52 176.2 8.8 1.2e-51 175.4 6.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME28278.1 - 1.3e-19 70.7 16.4 1.3e-19 70.7 11.4 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DNA_methylase PF00145.12 EME28279.1 - 1.1e-29 103.6 0.0 4.5e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase PHD PF00628.24 EME28279.1 - 3.9e-05 23.2 13.4 3.9e-05 23.2 9.3 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EME28279.1 - 0.29 10.4 8.9 0.12 11.6 3.5 2.2 2 0 0 2 2 2 0 PHD-finger PLAT PF01477.18 EME28280.1 - 7.8e-16 58.4 0.2 2e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 PLAT/LH2 domain C2 PF00168.25 EME28280.1 - 3.7e-11 42.7 0.0 1.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EME28280.1 - 0.00017 21.6 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) AAA_33 PF13671.1 EME28281.1 - 1.7e-23 83.1 0.1 1.3e-22 80.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME28281.1 - 2.6e-08 34.2 0.0 0.00017 21.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EME28281.1 - 1.5e-06 29.0 0.0 2.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME28281.1 - 7.8e-06 25.2 4.3 0.017 14.3 0.1 2.4 3 0 0 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EME28281.1 - 0.00067 18.8 0.0 0.0045 16.0 0.0 2.0 1 1 1 2 2 2 1 Zeta toxin 6PF2K PF01591.13 EME28281.1 - 0.00089 18.3 0.2 0.36 9.8 0.0 3.0 3 0 0 3 3 3 1 6-phosphofructo-2-kinase AAA_5 PF07728.9 EME28281.1 - 0.0018 17.9 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 EME28281.1 - 0.0031 17.1 0.1 0.0045 16.6 0.1 1.5 1 1 0 1 1 1 1 NACHT domain tRNA_lig_kinase PF08303.6 EME28281.1 - 0.0053 16.6 0.5 0.013 15.3 0.4 1.7 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.1 EME28281.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28281.1 - 0.0076 16.3 0.2 0.015 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EME28281.1 - 0.026 14.7 0.4 0.045 13.9 0.1 1.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EME28281.1 - 0.03 13.0 0.2 0.096 11.3 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit SKI PF01202.17 EME28281.1 - 0.039 13.8 1.2 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 Shikimate kinase DUF4451 PF14616.1 EME28281.1 - 0.046 13.4 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) SRP54 PF00448.17 EME28281.1 - 0.046 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EME28281.1 - 0.047 12.8 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EME28281.1 - 0.073 13.2 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 EME28281.1 - 0.074 12.6 0.3 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EME28281.1 - 0.1 11.9 0.2 0.97 8.7 0.0 2.4 1 1 1 2 2 2 0 Thymidylate kinase bZIP_1 PF00170.16 EME28283.1 - 1.5e-09 37.6 12.9 1.5e-09 37.6 9.0 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME28283.1 - 9.6e-06 25.3 14.7 9.6e-06 25.3 10.2 2.0 1 1 1 2 2 2 1 Basic region leucine zipper ubiquitin PF00240.18 EME28283.1 - 2.5e-05 23.5 0.1 5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Shugoshin_N PF07558.6 EME28283.1 - 0.023 14.4 1.3 0.048 13.3 0.9 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Rad60-SLD PF11976.3 EME28283.1 - 0.033 13.8 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like OmpH PF03938.9 EME28283.1 - 0.044 13.7 3.9 0.07 13.0 2.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.12 EME28283.1 - 0.37 11.1 19.9 0.029 14.6 10.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EME28284.1 - 2.6e-10 40.0 14.6 2.6e-10 40.0 10.1 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME28284.1 - 1.1e-05 25.0 15.1 1.1e-05 25.0 10.5 2.0 1 1 1 2 2 2 1 Basic region leucine zipper Shugoshin_N PF07558.6 EME28284.1 - 0.021 14.5 1.3 0.046 13.4 0.9 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region OmpH PF03938.9 EME28284.1 - 0.48 10.3 5.4 0.78 9.6 3.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.12 EME28284.1 - 0.55 10.5 21.8 0.04 14.1 11.3 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor PC_rep PF01851.17 EME28285.1 - 2.5e-06 27.3 5.4 3.3 8.1 0.2 6.0 4 0 0 4 4 4 4 Proteasome/cyclosome repeat GPAT_N PF14829.1 EME28285.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Pro_isomerase PF00160.16 EME28286.1 - 9.9e-11 42.0 0.0 2.4e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LicD PF04991.8 EME28286.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 LicD family Med9 PF07544.8 EME28286.1 - 0.11 12.2 1.7 0.25 11.1 1.2 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Nfu_N PF08712.6 EME28287.1 - 3.4e-31 106.7 0.0 1.1e-30 105.1 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EME28287.1 - 2.7e-17 62.2 0.1 4.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Myosin_tail_1 PF01576.14 EME28288.1 - 0.012 13.3 83.5 0.11 10.1 57.8 1.9 1 1 0 1 1 1 0 Myosin tail DUF869 PF05911.6 EME28288.1 - 0.081 11.1 72.9 0.23 9.6 10.5 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) DUF3584 PF12128.3 EME28288.1 - 0.11 9.8 76.8 1.2 6.3 53.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) LPP PF04728.8 EME28288.1 - 0.19 11.5 10.5 2.9 7.7 0.2 4.3 4 2 0 4 4 4 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 EME28288.1 - 0.42 9.7 15.7 4 6.5 3.0 3.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Ribosomal_S20p PF01649.13 EME28288.1 - 2 8.8 13.0 0.39 11.1 3.6 3.4 2 1 1 3 3 3 0 Ribosomal protein S20 DUF948 PF06103.6 EME28288.1 - 2.1 8.2 25.0 0.6 9.9 1.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EME28288.1 - 3.4 6.0 68.6 5.4 5.3 28.6 2.4 1 1 1 2 2 2 0 AAA domain Myosin_tail_1 PF01576.14 EME28289.1 - 0.023 12.4 79.9 0.0021 15.9 39.9 2.1 1 1 1 2 2 2 0 Myosin tail Ribosomal_S20p PF01649.13 EME28289.1 - 0.028 14.7 4.9 0.15 12.4 2.8 2.7 2 0 0 2 2 2 0 Ribosomal protein S20 LPP PF04728.8 EME28289.1 - 0.17 11.7 10.5 2.8 7.7 0.2 4.4 4 2 0 4 4 4 0 Lipoprotein leucine-zipper DUF869 PF05911.6 EME28289.1 - 0.17 10.0 72.7 0.29 9.3 10.7 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EME28289.1 - 0.19 10.9 15.4 4.1 6.4 3.0 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EME28289.1 - 0.74 9.6 93.0 0.024 14.5 20.5 5.4 1 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EME28289.1 - 2.2 8.2 25.2 0.58 10.0 1.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.1 EME28289.1 - 4.2 7.3 76.4 0.051 13.6 15.4 3.7 1 1 3 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 EME28289.1 - 4.8 5.5 66.5 0.66 8.3 26.4 2.3 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.3 EME28289.1 - 4.8 4.3 75.5 0.33 8.2 33.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Arch_ATPase PF01637.13 EME28291.1 - 0.00085 19.0 0.2 0.0072 16.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase Sugar_tr PF00083.19 EME28295.1 - 2.4e-70 237.3 23.9 2.9e-70 237.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28295.1 - 3.5e-23 81.8 30.7 3.8e-20 71.9 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME28296.1 - 9.1e-28 97.0 10.8 1e-27 96.8 7.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 EME28297.1 - 2.3e-23 82.5 1.6 2.5e-23 82.3 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28297.1 - 2.7e-12 46.1 8.0 3e-12 45.9 5.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_38C PF07748.8 EME28298.1 - 1e-63 215.7 0.0 1.4e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 EME28298.1 - 2e-63 214.2 0.2 1.1e-49 169.2 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EME28298.1 - 1.8e-21 76.1 0.2 8.5e-21 73.9 0.0 2.3 2 0 0 2 2 2 1 Alpha mannosidase, middle domain zf-C3HC4_3 PF13920.1 EME28299.1 - 7.3e-07 28.7 7.2 7.3e-07 28.7 5.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME28299.1 - 2.9e-05 23.8 11.8 7.5e-05 22.4 8.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME28299.1 - 0.00035 20.1 10.9 0.00089 18.8 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28299.1 - 0.00042 19.9 10.5 0.001 18.7 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME28299.1 - 0.0015 18.4 11.1 0.0015 18.4 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME28299.1 - 0.15 11.6 7.1 0.38 10.3 4.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EME28299.1 - 2.4 8.0 10.2 7.3 6.5 7.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prefoldin_3 PF13758.1 EME28301.1 - 0.0047 16.6 1.5 0.091 12.5 0.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit IncA PF04156.9 EME28301.1 - 0.0083 15.7 7.4 0.0094 15.5 5.1 1.1 1 0 0 1 1 1 1 IncA protein Laminin_II PF06009.7 EME28301.1 - 0.024 14.3 3.8 0.028 14.1 2.7 1.2 1 0 0 1 1 1 0 Laminin Domain II NuA4 PF09340.5 EME28301.1 - 0.025 14.1 4.0 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF1083 PF06452.6 EME28301.1 - 0.027 14.3 0.1 0.033 14.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1083) Mating_N PF12731.2 EME28301.1 - 0.047 13.5 0.7 0.068 13.0 0.5 1.4 1 1 0 1 1 1 0 Mating-type protein beta 1 YkuI_C PF10388.4 EME28301.1 - 0.062 12.9 1.4 0.078 12.6 1.0 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain DUF2408 PF10303.4 EME28301.1 - 0.062 13.4 3.1 0.072 13.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF2317 PF10079.4 EME28301.1 - 0.064 11.8 0.5 0.075 11.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Resolvase PF00239.16 EME28301.1 - 0.12 12.2 0.6 0.14 12.0 0.4 1.2 1 0 0 1 1 1 0 Resolvase, N terminal domain MtrG PF04210.8 EME28301.1 - 0.13 11.9 1.1 0.24 11.0 0.5 1.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tropomyosin PF00261.15 EME28301.1 - 0.15 11.1 7.1 1.4 7.9 0.5 2.0 1 1 1 2 2 2 0 Tropomyosin APG6 PF04111.7 EME28301.1 - 0.18 10.7 6.0 0.21 10.6 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EME28301.1 - 0.21 11.1 2.6 0.22 11.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nup54 PF13874.1 EME28301.1 - 0.24 11.0 2.4 0.31 10.6 1.7 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HemX PF04375.9 EME28301.1 - 0.25 9.9 2.0 0.29 9.6 1.4 1.0 1 0 0 1 1 1 0 HemX Frigida PF07899.6 EME28301.1 - 0.25 10.0 2.8 0.29 9.8 1.9 1.1 1 0 0 1 1 1 0 Frigida-like protein Syntaxin PF00804.20 EME28301.1 - 0.3 11.2 3.6 0.42 10.7 2.5 1.3 1 1 0 1 1 1 0 Syntaxin DUF3158 PF11358.3 EME28301.1 - 0.3 10.5 2.1 1.6 8.2 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3158) DUF2968 PF11180.3 EME28301.1 - 0.31 10.4 4.6 0.38 10.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 EME28301.1 - 0.31 8.8 3.2 0.35 8.6 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 EME28301.1 - 0.44 8.8 3.3 0.49 8.7 2.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Med9 PF07544.8 EME28301.1 - 0.51 10.0 4.3 2.3 8.0 2.9 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 EME28301.1 - 0.63 10.3 4.4 1.9 8.8 3.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.1 EME28301.1 - 0.98 9.4 7.0 2.1 8.3 4.2 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 STAT_alpha PF01017.15 EME28301.1 - 1 9.0 8.2 0.8 9.3 1.0 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Uds1 PF15456.1 EME28301.1 - 1.2 9.1 5.9 6.5 6.7 0.3 2.1 1 1 1 2 2 2 0 Up-regulated During Septation DUF2205 PF10224.4 EME28301.1 - 2.5 7.7 9.1 2.3 7.8 1.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) FlaC_arch PF05377.6 EME28301.1 - 3.5 7.5 5.5 9.5 6.2 0.9 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4635 PF15466.1 EME28301.1 - 4.7 6.5 7.8 5.6 6.2 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) ABC2_membrane PF01061.19 EME28302.1 - 7.7e-45 152.6 17.6 7.7e-45 152.6 12.2 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EME28302.1 - 1.3e-25 90.2 0.0 1e-13 51.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EME28302.1 - 2.2e-06 27.7 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EME28302.1 - 2.7e-06 26.6 0.2 0.0084 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EME28302.1 - 5e-06 26.0 0.0 0.002 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME28302.1 - 1.4e-05 25.2 0.0 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EME28302.1 - 2.5e-05 24.3 0.1 0.0082 16.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME28302.1 - 2.7e-05 24.9 0.0 0.013 16.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EME28302.1 - 6.7e-05 22.3 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EME28302.1 - 0.00018 21.8 0.0 0.029 14.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain PDR_assoc PF08370.6 EME28302.1 - 0.00022 20.6 1.2 0.00022 20.6 0.8 2.1 2 0 0 2 2 1 1 Plant PDR ABC transporter associated ABC_trans_N PF14510.1 EME28302.1 - 0.00024 21.1 0.0 0.00084 19.3 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_19 PF13245.1 EME28302.1 - 0.00048 19.8 0.1 0.6 9.9 0.0 2.4 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EME28302.1 - 0.00065 19.6 0.3 0.039 13.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EME28302.1 - 0.0014 18.2 0.1 0.096 12.3 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EME28302.1 - 0.0028 17.8 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EME28302.1 - 0.004 15.9 0.0 0.092 11.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EME28302.1 - 0.0041 16.8 0.0 0.76 9.4 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 EME28302.1 - 0.0059 16.5 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 EME28302.1 - 0.0076 15.7 2.1 0.081 12.3 0.2 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EME28302.1 - 0.01 15.9 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.1 EME28302.1 - 0.012 15.6 1.1 0.016 15.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EME28302.1 - 0.015 15.2 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EME28302.1 - 0.019 14.4 0.1 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PDR_CDR PF06422.7 EME28302.1 - 0.028 14.0 1.7 0.069 12.8 1.2 1.6 1 0 0 1 1 1 0 CDR ABC transporter RuvB_N PF05496.7 EME28302.1 - 0.03 13.3 0.1 3.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus Septin PF00735.13 EME28302.1 - 0.036 13.0 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Septin Miro PF08477.8 EME28302.1 - 0.042 14.3 0.0 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EME28302.1 - 0.047 13.1 0.0 4.5 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 EME28302.1 - 0.051 13.2 0.2 5.5 6.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EME28302.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EME28302.1 - 0.083 12.3 0.0 6.2 6.2 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EME28302.1 - 0.12 12.0 0.1 0.36 10.4 0.1 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EME28302.1 - 0.12 11.4 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin ArgK PF03308.11 EME28302.1 - 0.13 11.0 0.1 4.4 5.9 0.1 2.2 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 EME28302.1 - 0.2 10.8 0.1 9.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.12 EME28302.1 - 0.22 11.3 1.1 2.1 8.0 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 Ribosomal_S6 PF01250.12 EME28303.1 - 2e-11 43.5 0.0 3.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 RhoGEF PF00621.15 EME28304.1 - 1e-32 113.4 2.6 2.2e-32 112.3 1.8 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EME28304.1 - 3.1e-05 24.1 0.2 9.3e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EME28304.1 - 0.0009 19.4 2.1 0.0023 18.1 1.0 2.0 2 0 0 2 2 2 1 PH domain SMC_N PF02463.14 EME28306.1 - 8.7e-22 77.4 0.0 1.7e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME28306.1 - 2.3e-17 64.0 4.0 2.3e-17 64.0 2.8 5.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EME28306.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EME28306.1 - 0.051 12.9 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 EME28306.1 - 0.49 9.5 16.9 1.2 8.2 0.5 4.0 2 1 1 4 4 4 0 Reovirus sigma C capsid protein His_Phos_1 PF00300.17 EME28307.1 - 4e-29 101.7 0.0 4.9e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SBF PF01758.11 EME28308.1 - 4.1e-35 120.8 18.0 4.1e-35 120.8 12.5 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Ribosomal_S22 PF08136.6 EME28308.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family Flavi_NS4B PF01349.12 EME28308.1 - 0.2 10.5 1.8 0.27 10.1 0.1 1.8 1 1 0 1 1 1 0 Flavivirus non-structural protein NS4B E2F_TDP PF02319.15 EME28309.1 - 1.8e-14 53.0 0.1 5.4e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_TDP PF02319.15 EME28310.1 - 1.6e-14 53.2 0.1 5e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain WBS_methylT PF12589.3 EME28311.1 - 1.3e-13 51.2 7.0 2.3e-13 50.4 4.9 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EME28311.1 - 1.1e-09 38.7 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28311.1 - 5.1e-05 23.8 0.1 7.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28311.1 - 5.8e-05 22.8 0.0 8.7e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28311.1 - 0.00016 22.0 0.0 0.00035 21.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28311.1 - 0.00017 21.9 0.0 0.00027 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28311.1 - 0.00038 20.0 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EME28311.1 - 0.0021 18.1 0.0 0.0058 16.7 0.0 1.7 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 EME28311.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EME28311.1 - 0.051 13.0 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 DNA methylase Aldo_ket_red PF00248.16 EME28312.1 - 1.5e-23 83.0 0.0 1.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LLC1 PF14945.1 EME28313.1 - 3 8.1 15.3 1.6 9.0 0.0 3.3 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Mito_carr PF00153.22 EME28314.1 - 4.2e-60 199.4 0.0 5.9e-21 73.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Kinesin PF00225.18 EME28316.1 - 3.5e-107 357.9 0.5 8.5e-107 356.7 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 EME28316.1 - 0.06 13.1 6.0 0.14 11.9 0.1 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Pro_isomerase PF00160.16 EME28317.1 - 4.3e-18 65.9 0.0 5.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD rRNA_proc-arch PF13234.1 EME28318.1 - 6.9e-68 228.6 1.5 1.6e-67 227.5 1.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EME28318.1 - 2.4e-59 199.5 0.7 2.4e-59 199.5 0.5 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EME28318.1 - 1.6e-21 76.5 0.1 4.1e-20 71.9 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28318.1 - 1.1e-07 31.6 0.1 2.2e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EME28318.1 - 0.036 13.6 0.0 0.6 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2856 PF11043.3 EME28318.1 - 0.036 14.1 0.6 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) HSF_DNA-bind PF00447.12 EME28319.1 - 3.4e-29 101.0 1.0 3.4e-29 101.0 0.7 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding His_Phos_1 PF00300.17 EME28320.1 - 2.8e-27 95.7 0.2 3.3e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EME28320.1 - 0.00013 21.4 0.1 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SBP_bac_5 PF00496.17 EME28320.1 - 0.023 13.5 0.3 0.029 13.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle His_Phos_1 PF00300.17 EME28321.1 - 6.9e-18 65.2 0.1 7.6e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EME28321.1 - 0.00018 20.9 0.1 0.0002 20.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) cobW PF02492.14 EME28322.1 - 4.8e-58 195.5 3.4 4.5e-46 156.5 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EME28322.1 - 8e-18 63.9 0.2 7.8e-17 60.7 0.0 2.8 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain T2SE PF00437.15 EME28322.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EME28322.1 - 0.014 15.0 0.2 0.083 12.5 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EME28322.1 - 0.025 14.8 0.2 0.44 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME28322.1 - 0.03 14.0 0.2 0.24 11.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EME28322.1 - 0.031 14.3 0.7 0.21 11.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EME28322.1 - 0.085 12.8 0.2 0.87 9.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EME28322.1 - 0.15 11.7 0.0 0.46 10.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_D PF01813.12 EME28323.1 - 1.9e-60 203.7 0.9 2.4e-60 203.4 0.1 1.5 2 0 0 2 2 2 1 ATP synthase subunit D DUF733 PF05306.6 EME28323.1 - 0.087 13.1 0.9 0.23 11.7 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF733) 5_3_exonuc_N PF02739.11 EME28323.1 - 0.096 12.0 0.2 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain dCMP_cyt_deam_1 PF00383.17 EME28324.1 - 1.7e-17 62.9 0.3 2.1e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EME28324.1 - 4.1e-12 46.1 0.1 1.4e-11 44.4 0.1 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EME28324.1 - 0.0017 17.7 2.8 0.3 10.4 0.5 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases AAA PF00004.24 EME28325.1 - 1.9e-97 322.5 0.0 1.7e-48 164.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EME28325.1 - 4.3e-23 81.0 1.4 1.6e-22 79.2 0.1 2.7 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EME28325.1 - 7e-14 51.4 0.0 8e-06 25.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME28325.1 - 1e-12 48.9 0.1 2.8e-05 24.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EME28325.1 - 1.3e-12 47.9 0.0 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EME28325.1 - 2.3e-12 47.3 0.1 8.8e-05 22.5 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EME28325.1 - 3.5e-12 46.4 0.0 9.7e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME28325.1 - 3.9e-12 46.0 0.1 1.3e-06 28.1 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 EME28325.1 - 7.3e-12 44.7 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EME28325.1 - 7.8e-12 45.4 1.2 0.00032 20.8 0.1 4.4 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EME28325.1 - 1.7e-09 37.6 0.0 0.00079 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EME28325.1 - 4.5e-09 35.7 0.0 0.0026 16.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EME28325.1 - 2.1e-08 33.2 0.0 0.00088 18.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 EME28325.1 - 5.5e-08 32.7 0.1 0.22 11.1 0.0 3.8 2 2 1 3 3 3 3 Archaeal ATPase AAA_18 PF13238.1 EME28325.1 - 6e-08 33.0 0.0 0.012 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EME28325.1 - 1.2e-07 31.3 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EME28325.1 - 4.4e-07 30.0 0.0 0.0055 16.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EME28325.1 - 5.1e-07 29.0 0.2 0.028 13.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EME28325.1 - 8.3e-07 28.6 1.7 0.031 14.0 0.3 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_25 PF13481.1 EME28325.1 - 1.2e-06 28.1 2.5 0.22 10.9 0.0 4.1 2 2 1 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 EME28325.1 - 1.3e-06 28.4 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EME28325.1 - 1.4e-06 28.6 0.6 0.011 16.0 0.0 3.3 3 1 0 3 3 2 2 ABC transporter Sigma54_activat PF00158.21 EME28325.1 - 1.5e-06 27.8 0.0 0.014 14.9 0.0 3.2 3 1 0 3 3 2 2 Sigma-54 interaction domain NACHT PF05729.7 EME28325.1 - 2.8e-06 27.1 0.1 0.15 11.7 0.0 3.9 3 1 1 4 4 4 2 NACHT domain Viral_helicase1 PF01443.13 EME28325.1 - 6.3e-06 25.8 0.0 0.0014 18.1 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 EME28325.1 - 8.1e-06 25.6 0.0 0.054 13.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein KaiC PF06745.8 EME28325.1 - 9.7e-06 24.8 0.6 2.3 7.2 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EME28325.1 - 1.1e-05 25.4 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EME28325.1 - 1.3e-05 25.1 0.0 0.0035 17.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EME28325.1 - 1.6e-05 23.9 0.1 0.026 13.4 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EME28325.1 - 2.8e-05 23.1 0.0 0.1 11.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.1 EME28325.1 - 3.8e-05 23.3 0.0 0.34 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EME28325.1 - 0.00011 21.9 0.2 0.0014 18.4 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EME28325.1 - 0.00021 20.8 0.0 0.81 9.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EME28325.1 - 0.00054 18.9 0.0 0.15 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EME28325.1 - 0.00069 18.9 0.1 0.91 8.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NTPase_1 PF03266.10 EME28325.1 - 0.00071 19.3 0.3 1.4 8.6 0.0 3.8 3 1 0 3 3 3 1 NTPase SKI PF01202.17 EME28325.1 - 0.0015 18.4 0.2 1.8 8.3 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase DUF2075 PF09848.4 EME28325.1 - 0.0017 17.3 0.0 0.85 8.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 EME28325.1 - 0.0018 18.2 0.5 0.4 10.5 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_23 PF13476.1 EME28325.1 - 0.0027 18.0 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EME28325.1 - 0.0039 16.8 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EME28325.1 - 0.018 14.6 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EME28325.1 - 0.019 13.8 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EME28325.1 - 0.02 14.3 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.1 EME28325.1 - 0.028 14.4 0.9 11 5.8 0.7 3.2 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EME28325.1 - 0.03 13.8 0.3 22 4.5 0.0 3.4 2 2 1 4 4 3 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EME28325.1 - 0.034 13.6 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EME28325.1 - 0.038 13.4 1.7 2.4 7.4 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain KTI12 PF08433.5 EME28325.1 - 0.046 12.9 0.0 8.7 5.4 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EME28325.1 - 0.056 12.9 0.2 7.3 6.0 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.1 EME28325.1 - 0.058 12.9 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EME28325.1 - 0.062 12.2 0.1 5.2 5.9 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain PduV-EutP PF10662.4 EME28325.1 - 0.15 11.5 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 EME28325.1 - 0.19 10.3 0.0 2.2 6.8 0.0 2.2 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein DUF1995 PF09353.5 EME28326.1 - 1.2e-09 38.1 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) ISN1 PF06437.6 EME28326.1 - 0.11 11.1 0.3 0.17 10.5 0.2 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase CBS PF00571.23 EME28328.1 - 5.9e-23 80.3 0.0 2.5e-06 27.1 0.0 4.2 4 0 0 4 4 4 4 CBS domain DUF4147 PF13660.1 EME28328.1 - 0.063 12.3 0.1 0.35 9.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Cache_3 PF14827.1 EME28328.1 - 0.099 12.5 0.0 1.6 8.6 0.0 2.5 3 0 0 3 3 3 0 Sensory domain of two-component sensor kinase CBS PF00571.23 EME28329.1 - 2.4e-18 65.6 0.0 1.2e-06 28.1 0.0 3.2 3 0 0 3 3 3 3 CBS domain SPACA7 PF15307.1 EME28329.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 DUF2451 PF10474.4 EME28330.1 - 6.2e-29 101.4 3.0 3.4e-28 98.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 EME28330.1 - 2e-10 40.0 15.8 8.5e-10 37.9 10.9 2.1 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) IKKbetaNEMObind PF12179.3 EME28330.1 - 0.00057 19.6 1.8 0.02 14.6 0.0 3.6 2 0 0 2 2 2 1 I-kappa-kinase-beta NEMO binding domain COG5 PF10392.4 EME28330.1 - 0.00075 19.4 5.7 0.0037 17.2 4.0 2.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF4441 PF14536.1 EME28330.1 - 0.01 15.8 3.4 0.01 15.8 2.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4441) Syntaxin-6_N PF09177.6 EME28330.1 - 0.28 11.6 13.3 0.042 14.2 2.5 4.4 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DEAD PF00270.24 EME28331.1 - 4e-24 85.0 0.0 6.5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28331.1 - 2.9e-11 43.0 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pox_A32 PF04665.7 EME28331.1 - 0.00026 20.3 0.4 0.097 11.9 0.0 2.4 2 0 0 2 2 2 2 Poxvirus A32 protein ResIII PF04851.10 EME28331.1 - 0.00068 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit p450 PF00067.17 EME28332.1 - 3.3e-93 312.7 0.3 3.9e-93 312.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SBF PF01758.11 EME28333.1 - 3.2e-36 124.5 23.0 4.4e-36 124.0 16.0 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF4137 PF13593.1 EME28333.1 - 1.8e-16 60.1 18.8 2.2e-16 59.8 13.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 EME28333.1 - 0.096 10.9 9.1 0.19 9.9 6.3 1.5 1 0 0 1 1 1 0 Membrane transport protein ABC_membrane_2 PF06472.10 EME28334.1 - 5.8e-98 327.4 4.1 8.3e-98 326.9 2.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME28334.1 - 5.3e-17 62.4 0.0 1.5e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 EME28334.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EME28334.1 - 0.00068 19.6 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME28334.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EME28334.1 - 0.001 18.3 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME28334.1 - 0.0012 18.2 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EME28334.1 - 0.033 14.9 0.1 0.13 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 EME28334.1 - 0.067 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EME28334.1 - 0.078 12.3 0.0 1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME28334.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Asp PF00026.18 EME28335.1 - 9.1e-45 153.2 6.6 1.3e-44 152.7 4.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME28335.1 - 1.7e-18 66.6 0.0 3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EME28335.1 - 1.7e-13 50.8 10.1 1.7e-13 50.8 7.0 2.8 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME28335.1 - 0.00011 22.6 0.1 0.17 12.4 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EME28335.1 - 0.04 13.8 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EME28335.1 - 0.11 12.2 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 EME28336.1 - 5.5e-45 153.9 6.6 8e-45 153.4 4.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME28336.1 - 1.2e-18 67.1 0.0 2.2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EME28336.1 - 1.2e-13 51.2 10.1 1.2e-13 51.2 7.0 2.9 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME28336.1 - 7e-05 23.2 0.1 0.14 12.6 0.0 2.8 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EME28336.1 - 0.029 14.2 0.0 4.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EME28336.1 - 0.085 12.6 0.1 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ribosomal_S8 PF00410.14 EME28337.1 - 2.1e-12 47.0 0.0 2.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 G-patch PF01585.18 EME28338.1 - 6.8e-06 25.7 0.5 2.3e-05 24.0 0.2 2.1 2 0 0 2 2 2 1 G-patch domain DUF4537 PF15057.1 EME28338.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) G-patch_2 PF12656.2 EME28338.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 DExH-box splicing factor binding site G-patch PF01585.18 EME28339.1 - 6.3e-06 25.8 0.5 2.2e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 G-patch domain DUF4537 PF15057.1 EME28339.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) G-patch_2 PF12656.2 EME28339.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 DExH-box splicing factor binding site MSC PF09402.5 EME28341.1 - 0.077 11.6 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF1887 PF09002.6 EME28342.1 - 0.0071 14.8 0.1 0.0075 14.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF4332 PF14229.1 EME28342.1 - 0.047 13.6 0.6 0.067 13.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) APG6 PF04111.7 EME28342.1 - 0.083 11.9 4.6 0.1 11.5 3.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TroA PF01297.12 EME28342.1 - 0.13 11.4 0.8 0.18 11.0 0.5 1.1 1 0 0 1 1 1 0 Periplasmic solute binding protein family Rad10 PF03834.9 EME28343.1 - 2.8e-17 62.1 0.3 6e-17 61.0 0.2 1.6 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EME28343.1 - 1.7e-12 47.2 0.0 4.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EME28343.1 - 6.4e-06 25.5 0.0 1.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EME28343.1 - 2.1e-05 24.3 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif TOM20_plant PF06552.7 EME28343.1 - 0.022 14.3 0.4 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 HHH_3 PF12836.2 EME28343.1 - 0.023 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.10 EME28343.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain UQ_con PF00179.21 EME28344.1 - 1.3e-52 176.9 0.0 1.5e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME28344.1 - 0.00015 21.6 0.4 0.00033 20.5 0.3 1.7 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EME28344.1 - 0.00063 19.4 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EME28345.1 - 2e-32 111.4 0.0 3.4e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EME28345.1 - 3.8e-14 52.0 0.5 8e-14 51.0 0.4 1.6 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EME28345.1 - 4.6e-06 26.0 0.1 7.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glutaredoxin2_C PF04399.8 EME28345.1 - 0.006 16.1 0.2 0.015 14.9 0.1 1.7 2 0 0 2 2 2 1 Glutaredoxin 2, C terminal domain Tropomyosin_1 PF12718.2 EME28345.1 - 0.72 9.7 7.1 1.4 8.7 4.9 1.5 1 0 0 1 1 1 0 Tropomyosin like Pyr_redox_2 PF07992.9 EME28346.1 - 1.8e-26 93.2 0.0 1.9e-25 89.9 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME28346.1 - 2.7e-13 50.1 0.0 4.5e-11 43.0 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME28346.1 - 0.00018 21.6 0.0 0.014 15.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME28347.1 - 1.8e-26 93.2 0.0 1.3e-25 90.5 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME28347.1 - 2.7e-13 50.1 0.0 4.4e-11 43.0 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME28347.1 - 0.00017 21.7 0.0 0.014 15.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase LSM PF01423.17 EME28348.1 - 8.9e-16 57.1 0.2 1.3e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME28348.1 - 0.00028 20.7 0.1 0.00037 20.3 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Tymo_45kd_70kd PF03251.8 EME28348.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein BPL_C PF02237.12 EME28348.1 - 0.11 12.1 0.5 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain API5 PF05918.6 EME28348.1 - 0.17 10.3 6.1 0.2 10.1 4.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Adaptin_N PF01602.15 EME28349.1 - 1e-96 324.3 4.4 1.7e-96 323.6 3.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EME28349.1 - 1.9e-10 41.0 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EME28349.1 - 7.7e-09 35.7 2.3 0.1 12.8 0.0 5.4 4 2 1 5 5 5 2 HEAT repeats Cnd1 PF12717.2 EME28349.1 - 6e-06 26.2 2.2 0.028 14.2 0.1 4.4 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EME28349.1 - 2.8e-05 23.8 1.2 0.28 11.3 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Cohesin_HEAT PF12765.2 EME28349.1 - 0.038 13.9 0.2 0.18 11.8 0.2 2.3 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Nuf2 PF03800.9 EME28349.1 - 0.062 13.2 0.1 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Nuf2 family Nipped-B_C PF12830.2 EME28349.1 - 0.13 11.9 1.4 1.1 8.8 0.0 3.1 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus HSP70 PF00012.15 EME28350.1 - 3.3e-44 150.7 0.1 7.1e-34 116.6 0.1 2.9 1 1 0 2 2 2 2 Hsp70 protein HSP70 PF00012.15 EME28351.1 - 1.1e-46 158.9 0.5 3.5e-36 124.2 0.3 3.1 1 1 0 2 2 2 2 Hsp70 protein cwf21 PF08312.7 EME28351.1 - 0.48 10.3 5.3 0.24 11.2 0.1 3.3 4 1 0 4 4 4 0 cwf21 domain DUF393 PF04134.7 EME28353.1 - 1e-21 78.1 0.0 1.9e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 FAD_binding_1 PF00667.15 EME28354.1 - 4.2e-37 127.7 0.1 1.1e-23 83.8 0.0 2.6 2 1 1 3 3 3 2 FAD binding domain Flavodoxin_1 PF00258.20 EME28354.1 - 1.2e-29 103.1 0.0 2e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EME28354.1 - 0.00071 20.1 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME28354.1 - 0.045 13.8 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF3830 PF12903.2 EME28354.1 - 0.16 11.3 0.0 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) DUF202 PF02656.10 EME28355.1 - 1.9e-16 60.0 4.4 1.9e-16 60.0 3.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1625 PF07787.7 EME28355.1 - 0.044 13.0 3.5 0.058 12.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DctQ PF04290.7 EME28355.1 - 0.22 11.2 5.8 0.3 10.8 4.0 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component YtpI PF14007.1 EME28355.1 - 1.2 9.0 7.1 0.066 13.1 1.0 1.8 2 1 0 2 2 2 0 YtpI-like protein MHYT PF03707.11 EME28355.1 - 3.5 7.8 10.3 8.2 6.6 0.8 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Peripla_BP_2 PF01497.13 EME28356.1 - 0.0044 16.1 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein FixQ PF05545.6 EME28356.1 - 7.8 6.2 9.6 0.079 12.6 0.9 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Nudix_N_2 PF14803.1 EME28357.1 - 0.016 14.8 3.4 0.037 13.7 2.4 1.6 1 0 0 1 1 1 0 Nudix N-terminal DZR PF12773.2 EME28357.1 - 0.092 12.5 1.5 0.19 11.5 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EME28357.1 - 0.13 12.0 2.3 0.35 10.7 1.6 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain ABC2_membrane PF01061.19 EME28358.1 - 4.5e-37 127.2 20.3 7.6e-37 126.5 14.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME28358.1 - 4.4e-28 98.2 0.1 7.7e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME28358.1 - 7.5e-09 35.9 4.8 2.7e-06 27.5 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28358.1 - 4.8e-08 33.1 0.1 9.8e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EME28358.1 - 5.3e-05 22.7 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME28358.1 - 7.9e-05 21.6 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 EME28358.1 - 8.1e-05 23.4 0.2 0.00024 21.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME28358.1 - 0.00011 21.8 0.2 0.0037 16.7 0.2 2.2 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EME28358.1 - 0.00021 20.5 0.1 0.00036 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EME28358.1 - 0.0003 20.0 0.2 0.0012 18.0 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME28358.1 - 0.00041 20.7 0.0 0.00071 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME28358.1 - 0.00091 18.7 0.6 0.002 17.6 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.17 EME28358.1 - 0.0021 16.9 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EME28358.1 - 0.0024 17.9 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME28358.1 - 0.0028 17.9 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME28358.1 - 0.0039 16.8 0.1 0.017 14.8 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_28 PF13521.1 EME28358.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EME28358.1 - 0.01 15.5 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EME28358.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EME28358.1 - 0.017 15.0 0.6 0.043 13.6 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EME28358.1 - 0.019 14.5 0.2 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME28358.1 - 0.023 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EME28358.1 - 0.027 14.6 0.3 0.12 12.5 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EME28358.1 - 0.032 13.6 0.2 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EME28358.1 - 0.035 14.0 0.2 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EME28358.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EME28358.1 - 0.039 13.6 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.1 EME28358.1 - 0.042 13.7 0.1 0.17 11.8 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EME28358.1 - 0.055 13.3 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME28358.1 - 0.063 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.13 EME28358.1 - 0.074 12.3 0.1 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Virul_Fac PF10139.4 EME28358.1 - 0.086 10.7 1.0 3.8 5.3 0.0 2.1 2 0 0 2 2 2 0 Putative bacterial virulence factor UPF0079 PF02367.12 EME28358.1 - 0.088 12.4 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EME28358.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PWWP PF00855.12 EME28359.1 - 4.4e-16 58.8 5.0 4.4e-16 58.8 3.5 2.9 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.6 EME28359.1 - 9.7e-11 41.0 0.0 2.5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pribosyltran PF00156.22 EME28360.1 - 1.2e-16 60.5 0.0 1.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DNA_pol3_beta PF00712.14 EME28360.1 - 0.023 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain LETM1 PF07766.8 EME28361.1 - 0.00019 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EME28361.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 SAP domain Zn_Tnp_IS1 PF03811.8 EME28361.1 - 0.093 12.2 0.2 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain FNIP_N PF14636.1 EME28361.1 - 9.9 6.6 8.1 74 3.8 5.5 2.5 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Evr1_Alr PF04777.8 EME28362.1 - 3.2e-25 87.8 0.2 4.9e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TLV_coat PF00429.14 EME28362.1 - 0.059 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Ribosomal_S7 PF00177.16 EME28363.1 - 1.6e-26 92.6 0.0 1.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SusD-like_3 PF14322.1 EME28363.1 - 0.15 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Ribosomal_S7 PF00177.16 EME28364.1 - 1.6e-26 92.6 0.0 1.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SusD-like_3 PF14322.1 EME28364.1 - 0.15 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DRMBL PF07522.9 EME28365.1 - 2.7e-28 98.2 0.1 6.6e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EME28365.1 - 9.7e-11 41.5 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SAM_2 PF07647.12 EME28365.1 - 2.1e-10 40.2 0.1 4.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME28365.1 - 3.2e-08 33.6 0.2 8.5e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RMMBL PF07521.7 EME28365.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EME28365.1 - 0.047 13.3 0.1 0.15 11.6 0.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily MttA_Hcf106 PF02416.11 EME28366.1 - 7.7e-13 47.3 2.2 1.4e-12 46.5 1.5 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family GnsAB PF08178.6 EME28366.1 - 0.0026 17.3 0.2 0.0046 16.5 0.2 1.4 1 0 0 1 1 1 1 GnsA/GnsB family YtxH PF12732.2 EME28366.1 - 0.0049 17.1 0.3 0.0076 16.5 0.2 1.3 1 0 0 1 1 1 1 YtxH-like protein UvrB PF12344.3 EME28366.1 - 0.026 14.0 1.2 0.081 12.4 0.2 2.2 1 1 1 2 2 2 0 Ultra-violet resistance protein B Fer4 PF00037.22 EME28367.1 - 3.6e-14 51.6 17.7 1.1e-08 34.2 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EME28367.1 - 1.1e-12 48.0 11.4 1.8e-12 47.4 7.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EME28367.1 - 3.2e-11 42.8 25.0 1.3e-08 34.4 9.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EME28367.1 - 5.9e-11 42.9 6.7 2e-05 25.2 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EME28367.1 - 5.3e-10 39.4 11.4 9.6e-10 38.5 7.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EME28367.1 - 5.8e-10 38.8 4.5 0.0001 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EME28367.1 - 1.7e-08 34.3 22.2 4.9e-06 26.4 8.7 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EME28367.1 - 7.8e-08 31.8 18.4 0.00072 19.3 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 EME28367.1 - 9.8e-08 31.4 15.5 0.00026 20.7 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EME28367.1 - 3e-06 27.1 12.4 0.00076 19.6 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EME28367.1 - 7.6e-06 26.2 9.3 0.0089 16.4 0.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EME28367.1 - 2.3e-05 24.6 11.7 0.00039 20.7 8.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 EME28367.1 - 3.5e-05 24.0 10.6 0.014 15.7 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EME28367.1 - 0.0029 18.1 13.2 0.2 12.2 2.3 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EME28367.1 - 0.0076 16.7 19.2 0.014 15.8 4.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EME28367.1 - 0.19 11.8 5.2 0.9 9.6 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Methyltransf_16 PF10294.4 EME28368.1 - 2.2e-11 43.5 0.0 3.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EME28368.1 - 0.00034 20.3 0.1 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28368.1 - 0.0051 17.2 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28368.1 - 0.0067 16.9 0.0 0.017 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28368.1 - 0.0069 15.9 0.5 0.04 13.4 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain PPDK_N PF01326.14 EME28369.1 - 1.1e-87 294.2 0.1 1.6e-87 293.6 0.1 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 EME28369.1 - 1.7e-60 204.4 0.0 3.3e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 EME28369.1 - 8.9e-24 82.8 0.9 3.4e-23 81.0 0.6 2.0 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Ist1 PF03398.9 EME28370.1 - 9.4e-37 125.9 0.0 1.2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DXP_synthase_N PF13292.1 EME28371.1 - 1.2e-104 349.0 0.0 4.8e-104 347.0 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 EME28371.1 - 9.4e-36 122.9 0.0 1.8e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME28371.1 - 4e-23 81.7 0.0 9.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 EME28371.1 - 5.3e-07 28.7 0.0 0.013 14.3 0.0 2.9 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 EME28371.1 - 4.3e-06 25.6 0.0 7.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EME28371.1 - 6e-06 25.9 0.1 1.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PMG PF05287.7 EME28371.1 - 0.12 12.1 1.5 0.36 10.6 0.3 2.0 2 0 0 2 2 2 0 PMG protein Tubulin PF00091.20 EME28372.1 - 6.3e-69 232.0 0.0 8.7e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME28372.1 - 1.3e-50 170.6 0.2 1.9e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EME28372.1 - 0.00067 19.1 0.0 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain TPR_11 PF13414.1 EME28373.1 - 3.8e-24 84.1 9.1 1.8e-08 33.9 0.0 5.4 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EME28373.1 - 3.7e-23 79.5 15.5 0.00046 19.9 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 EME28373.1 - 3.6e-20 70.6 12.4 3.3e-05 23.3 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME28373.1 - 4.7e-17 60.4 5.3 0.003 17.2 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME28373.1 - 4.8e-16 58.4 15.2 1.3e-08 34.5 0.1 6.9 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME28373.1 - 1.4e-15 57.3 0.8 0.0075 16.5 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EME28373.1 - 3.7e-13 49.3 26.7 0.00031 20.8 0.0 6.3 4 1 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EME28373.1 - 1.5e-12 47.7 8.9 0.0002 21.9 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME28373.1 - 1.6e-11 43.7 8.1 0.013 16.1 0.0 6.4 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME28373.1 - 4.9e-11 41.5 8.0 0.00091 18.8 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME28373.1 - 1.6e-06 27.8 0.5 0.0032 17.2 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME28373.1 - 2.4e-06 27.6 14.4 0.015 15.7 0.0 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME28373.1 - 1.3e-05 25.0 1.0 0.32 11.3 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME28373.1 - 1.9e-05 24.4 10.0 0.2 11.6 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EME28373.1 - 0.0006 19.9 2.1 9 7.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME28373.1 - 0.036 13.9 3.7 19 5.2 0.0 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Met_gamma_lyase PF06838.6 EME28374.1 - 1.7e-166 553.5 0.0 1.9e-166 553.3 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.15 EME28374.1 - 2.6e-07 29.2 0.0 3.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EME28374.1 - 0.038 12.7 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HhH-GPD PF00730.20 EME28374.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PMP1_2 PF08114.6 EME28375.1 - 0.0062 15.9 0.3 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 ATPase proteolipid family DUF692 PF05114.8 EME28375.1 - 0.042 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) She9_MDM33 PF05546.6 EME28375.1 - 0.053 13.0 1.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 She9 / Mdm33 family DUF1772 PF08592.6 EME28375.1 - 0.083 12.6 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Polysacc_synt_C PF14667.1 EME28375.1 - 0.083 12.6 4.3 0.17 11.7 3.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Adeno_E3_CR2 PF02439.10 EME28375.1 - 0.088 12.3 2.2 0.2 11.1 1.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Vpu PF00558.14 EME28375.1 - 0.095 12.2 1.4 0.19 11.2 0.2 2.0 2 0 0 2 2 2 0 Vpu protein YrhC PF14143.1 EME28375.1 - 0.55 10.2 4.2 3.1 7.8 1.1 2.4 2 0 0 2 2 2 0 YrhC-like protein DUF485 PF04341.7 EME28375.1 - 0.65 9.7 4.4 1.4 8.7 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Sugar_tr PF00083.19 EME28376.1 - 6.3e-90 301.9 27.1 7.7e-90 301.6 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28376.1 - 8.3e-25 87.2 44.4 4.9e-15 55.0 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EamA PF00892.15 EME28378.1 - 0.00015 21.8 5.8 0.00025 21.0 4.0 1.4 1 0 0 1 1 1 1 EamA-like transporter family TauE PF01925.14 EME28378.1 - 0.018 14.4 4.5 0.027 13.9 3.1 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF1275 PF06912.6 EME28378.1 - 0.025 13.7 2.8 0.03 13.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) SAM_1 PF00536.25 EME28379.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UvrD-helicase PF00580.16 EME28379.1 - 0.23 10.7 1.6 1.7 7.8 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SAM_1 PF00536.25 EME28380.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UvrD-helicase PF00580.16 EME28380.1 - 0.23 10.7 1.6 1.7 7.8 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Arch_ATPase PF01637.13 EME28381.1 - 0.011 15.4 0.4 0.06 13.0 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Sugar_tr PF00083.19 EME28383.1 - 2.7e-90 303.1 31.8 3.2e-90 302.8 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28383.1 - 1.4e-22 79.9 25.6 1.4e-22 79.9 17.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1435 PF07256.7 EME28383.1 - 1.8 8.5 6.0 7.6 6.6 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) ADH_N PF08240.7 EME28384.1 - 5.4e-26 90.4 1.3 5.4e-26 90.4 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME28384.1 - 3e-21 75.3 0.0 4.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 EME28384.1 - 0.028 13.5 3.5 0.074 12.2 2.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Biotin_lipoyl PF00364.17 EME28384.1 - 0.12 12.0 0.4 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme UBA_4 PF14555.1 EME28385.1 - 1.6e-11 43.5 0.2 3.3e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UCH PF00443.24 EME28385.1 - 0.00018 20.7 1.4 0.00028 20.1 0.8 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GRAM PF02893.15 EME28385.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF4370 PF14290.1 EME28385.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) ECM11 PF15463.1 EME28385.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.4 2 0 0 2 2 2 0 Extracellular mutant protein 11 DUF4637 PF15470.1 EME28385.1 - 0.6 9.7 3.0 1.3 8.6 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF202 PF02656.10 EME28386.1 - 1.1e-13 51.1 4.1 5e-13 49.0 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Chordopox_A13L PF05961.6 EME28386.1 - 0.0051 16.7 4.8 0.32 10.9 0.0 2.8 3 0 0 3 3 3 2 Chordopoxvirus A13L protein SdpI PF13630.1 EME28386.1 - 0.0052 16.4 1.4 2.2 8.0 0.6 2.2 2 0 0 2 2 2 2 SdpI/YhfL protein family DUF373 PF04123.8 EME28386.1 - 0.0073 15.3 0.5 0.013 14.5 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF373) ATG22 PF11700.3 EME28386.1 - 0.024 13.1 0.4 0.028 12.8 0.3 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4234 PF14018.1 EME28386.1 - 0.027 14.2 3.4 0.063 13.0 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DctQ PF04290.7 EME28386.1 - 0.027 14.2 1.3 0.038 13.7 0.8 1.3 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2975 PF11188.3 EME28386.1 - 0.05 13.3 1.8 0.11 12.1 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) CopD PF05425.8 EME28386.1 - 0.064 13.4 0.9 0.093 12.9 0.7 1.2 1 0 0 1 1 1 0 Copper resistance protein D ATG27 PF09451.5 EME28386.1 - 0.082 12.1 0.2 0.082 12.1 0.1 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 NDUF_B12 PF08122.7 EME28386.1 - 0.1 12.3 1.3 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF998 PF06197.8 EME28386.1 - 0.1 11.8 2.7 0.18 11.0 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF3317 PF11779.3 EME28386.1 - 0.23 10.9 5.7 2.1 7.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) DUF2207 PF09972.4 EME28386.1 - 0.34 9.4 1.5 0.67 8.4 1.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1206 PF06724.6 EME28386.1 - 0.38 10.5 2.7 17 5.2 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.11 EME28386.1 - 1 8.0 6.4 3.7 6.1 0.8 2.1 1 1 0 2 2 2 0 Major Facilitator Superfamily FUSC_2 PF13515.1 EME28386.1 - 1.2 9.0 7.0 2.2 8.2 4.8 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein-like PsbN PF02468.10 EME28386.1 - 1.4 8.6 5.8 9.2 5.9 0.3 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF4199 PF13858.1 EME28386.1 - 2.4 8.0 9.0 2.2 8.2 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) MARVEL PF01284.18 EME28386.1 - 2.7 7.7 7.3 14 5.4 5.1 1.9 1 1 0 1 1 1 0 Membrane-associating domain DUF4131 PF13567.1 EME28386.1 - 5.6 6.3 7.1 10 5.4 4.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CHCH PF06747.8 EME28387.1 - 6.5e-08 32.2 5.1 8.6e-08 31.9 3.5 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EME28387.1 - 0.0018 18.0 4.0 0.0035 17.1 2.7 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EME28387.1 - 0.031 14.3 3.5 0.19 11.7 2.4 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 BEN PF10523.4 EME28387.1 - 0.031 14.3 0.2 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 BEN domain DUF148 PF02520.12 EME28387.1 - 0.048 13.4 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Sec2p PF06428.6 EME28387.1 - 0.082 12.7 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Telomere_Sde2 PF13019.1 EME28388.1 - 1.8e-21 76.4 1.2 1.8e-21 76.4 0.8 1.6 1 1 0 1 1 1 1 Telomere stability and silencing DUF2374 PF09574.5 EME28388.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Glyco_hydro_35 PF01301.14 EME28389.1 - 2.6e-92 309.5 2.2 4.6e-92 308.7 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 WD40 PF00400.27 EME28389.1 - 2e-07 30.6 0.5 0.016 15.1 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2415 PF10313.4 EME28389.1 - 0.0007 19.2 0.1 0.36 10.5 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised protein domain (DUF2415) Metallophos PF00149.23 EME28390.1 - 5.8e-29 100.9 0.4 1.1e-28 99.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EME28390.1 - 3.9e-19 68.4 0.3 8.5e-19 67.3 0.2 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EME28390.1 - 9.9e-17 60.3 12.2 5.2e-12 45.2 4.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME28390.1 - 2.1e-06 27.1 12.7 4.7e-05 22.8 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME28390.1 - 4.7e-06 26.1 13.5 0.0023 17.6 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME28390.1 - 0.0028 18.2 4.7 0.13 12.9 1.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME28390.1 - 0.032 14.0 3.8 0.39 10.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME28390.1 - 0.16 12.2 1.6 2.9 8.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME28390.1 - 0.38 11.3 4.9 14 6.4 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME28390.1 - 0.46 10.4 2.6 7.9 6.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EME28390.1 - 5.2 7.0 8.6 0.93 9.4 2.7 2.2 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain LMBR1 PF04791.11 EME28391.1 - 2.5e-28 98.9 25.4 5.1e-20 71.5 3.2 2.2 2 1 0 2 2 2 2 LMBR1-like membrane protein PPR_2 PF13041.1 EME28392.1 - 3.3e-56 187.0 12.7 8.3e-11 41.6 0.0 12.6 6 2 7 13 13 13 10 PPR repeat family PPR PF01535.15 EME28392.1 - 5.8e-45 148.1 24.1 7.2e-06 25.6 0.0 13.7 15 0 0 15 15 14 8 PPR repeat PPR_3 PF13812.1 EME28392.1 - 2.5e-36 120.8 10.8 0.00042 20.3 0.0 10.9 12 0 0 12 12 10 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME28392.1 - 3.4e-33 112.8 11.9 1.6e-05 24.2 0.0 10.5 12 0 0 12 12 12 6 PPR repeat FeThRed_A PF02941.10 EME28392.1 - 3.9e-15 55.5 0.2 8.2e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain TPR_14 PF13428.1 EME28392.1 - 1.9e-06 27.9 0.4 3.8 8.4 0.0 6.3 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME28392.1 - 0.00014 22.3 0.0 0.0068 17.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME28392.1 - 0.00032 20.5 3.2 2.3 8.2 0.1 5.4 3 1 2 5 5 5 1 Tetratricopeptide repeat RNA_pol_Rpb1_4 PF05000.12 EME28392.1 - 0.0085 15.8 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ATP13 PF12921.2 EME28392.1 - 0.0096 15.2 0.5 1 8.6 0.0 4.0 4 1 1 5 5 5 1 Mitochondrial ATPase expression Clathrin PF00637.15 EME28392.1 - 0.01 15.4 1.5 1 8.9 0.0 4.2 4 1 1 5 5 5 0 Region in Clathrin and VPS Apc3 PF12895.2 EME28392.1 - 0.016 15.3 3.3 0.4 10.8 0.1 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EME28392.1 - 0.059 13.1 3.1 22 5.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.12 EME28392.1 - 0.83 9.9 5.1 9.3 6.5 0.0 3.8 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Memo PF01875.12 EME28394.1 - 1.3e-74 250.5 0.0 1.6e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ADIP PF11559.3 EME28395.1 - 2.4e-11 43.7 22.8 2.4e-11 43.7 15.8 3.0 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EME28395.1 - 0.00035 20.4 17.1 0.00035 20.4 11.9 3.0 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF489 PF04356.7 EME28395.1 - 0.0076 15.8 6.1 0.0076 15.8 4.2 3.0 3 1 1 4 4 4 1 Protein of unknown function (DUF489) PhoQ_Sensor PF08918.5 EME28395.1 - 0.1 12.1 0.1 0.1 12.1 0.1 3.0 3 0 0 3 3 3 0 PhoQ Sensor WD40 PF00400.27 EME28396.1 - 5.6e-27 92.6 17.0 1.3e-05 24.9 0.9 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat SNARE_assoc PF09335.6 EME28397.1 - 3.1e-14 53.2 9.5 3.1e-14 53.2 6.6 2.3 1 1 1 2 2 2 2 SNARE associated Golgi protein DUF2165 PF09933.4 EME28397.1 - 0.008 15.9 3.4 0.008 15.9 2.3 1.9 1 1 1 2 2 2 1 Predicted small integral membrane protein (DUF2165) ABC2_membrane_3 PF12698.2 EME28397.1 - 8 5.3 17.1 10 5.0 11.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RNA_pol_A_bac PF01000.21 EME28398.1 - 6.1e-30 103.6 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EME28398.1 - 6.1e-07 28.4 0.0 6.8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rep_fac_C PF08542.6 EME28399.1 - 2e-19 69.3 0.2 2.8e-18 65.6 0.0 2.8 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EME28399.1 - 9.4e-12 44.8 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EME28399.1 - 3.7e-05 22.6 0.0 0.00011 21.0 0.0 1.8 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EME28399.1 - 0.00022 21.4 0.0 0.00074 19.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EME28399.1 - 0.001 18.5 0.1 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EME28399.1 - 0.002 18.2 0.1 0.035 14.2 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EME28399.1 - 0.0037 17.2 0.0 0.33 10.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EME28399.1 - 0.0068 15.1 0.2 1.5 7.4 0.0 3.0 2 1 1 3 3 3 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EME28399.1 - 0.01 15.8 0.1 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 EME28399.1 - 0.029 13.4 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SAGA-Tad1 PF12767.2 EME28400.1 - 1.2e-13 51.3 4.4 6.7e-13 48.8 3.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit EIIBC-GUT_N PF03612.9 EME28400.1 - 0.43 10.1 1.8 3.5 7.1 1.2 2.2 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OTU PF02338.14 EME28401.1 - 2e-10 41.2 0.0 7.2e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease APG17 PF04108.7 EME28401.1 - 0.00012 20.9 4.9 0.00012 20.9 3.4 1.8 1 1 1 2 2 2 1 Autophagy protein Apg17 DUF948 PF06103.6 EME28401.1 - 0.019 14.8 5.7 2.4 8.1 0.1 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3349 PF11829.3 EME28401.1 - 0.063 13.7 0.4 17 5.9 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Peptidase_C65 PF10275.4 EME28401.1 - 0.068 12.5 7.2 1.6 8.0 0.0 3.6 2 1 0 3 3 3 0 Peptidase C65 Otubain Adenylsucc_synt PF00709.16 EME28401.1 - 0.082 11.5 0.4 0.18 10.4 0.3 1.5 1 0 0 1 1 1 0 Adenylosuccinate synthetase Baculo_PEP_C PF04513.7 EME28401.1 - 1.1 9.0 8.0 2 8.2 1.0 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EME28401.1 - 3.9 7.2 5.7 2 8.2 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF445 PF04286.7 EME28401.1 - 6.4 6.1 10.0 12 5.3 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Prefoldin_2 PF01920.15 EME28401.1 - 7.2 6.4 13.4 14 5.4 0.1 3.8 3 1 0 3 3 3 0 Prefoldin subunit Syntaxin PF00804.20 EME28401.1 - 8.6 6.5 14.0 6.2 7.0 3.3 2.9 2 1 1 3 3 3 0 Syntaxin OTU PF02338.14 EME28402.1 - 6.4e-12 46.1 0.0 2.3e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease APG17 PF04108.7 EME28402.1 - 0.00017 20.5 5.2 0.00017 20.5 3.6 1.8 1 1 1 2 2 2 2 Autophagy protein Apg17 Peptidase_C65 PF10275.4 EME28402.1 - 0.00019 20.8 8.0 0.0023 17.3 0.0 3.6 2 1 0 3 3 3 1 Peptidase C65 Otubain DUF948 PF06103.6 EME28402.1 - 0.023 14.5 5.7 2.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3349 PF11829.3 EME28402.1 - 0.076 13.4 0.4 18 5.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Adenylsucc_synt PF00709.16 EME28402.1 - 0.091 11.4 0.4 0.19 10.3 0.3 1.5 1 0 0 1 1 1 0 Adenylosuccinate synthetase Baculo_PEP_C PF04513.7 EME28402.1 - 1.4 8.7 8.0 2.2 8.0 1.0 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.7 EME28402.1 - 5.1 6.5 9.5 8.7 5.7 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin PF00804.20 EME28402.1 - 6.6 6.9 13.3 5.3 7.2 3.0 2.9 2 1 0 3 3 3 0 Syntaxin Pkinase PF00069.20 EME28403.1 - 2.7e-57 193.8 0.0 6.2e-57 192.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28403.1 - 3.2e-37 127.9 0.0 2.6e-36 125.0 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME28403.1 - 0.0089 15.7 0.3 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME28403.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PspA_IM30 PF04012.7 EME28404.1 - 2.1e-44 151.5 32.5 2.7e-44 151.1 22.5 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF2120 PF09893.4 EME28404.1 - 0.0025 17.7 0.6 0.0052 16.7 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2120) RTX_C PF08339.5 EME28404.1 - 0.017 14.8 1.8 0.027 14.1 1.2 1.4 1 0 0 1 1 1 0 RTX C-terminal domain LAGLIDADG_WhiA PF14527.1 EME28404.1 - 0.047 13.5 1.9 0.12 12.2 1.3 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Herpes_UL6 PF01763.11 EME28404.1 - 0.12 10.5 10.2 0.17 10.0 6.8 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Nup54 PF13874.1 EME28404.1 - 0.95 9.1 21.8 0.089 12.4 7.2 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 EME28404.1 - 2.5 7.2 9.9 2.7 7.0 2.8 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Scaffolding_pro PF11418.3 EME28404.1 - 3.3 8.0 8.5 1.4 9.2 2.2 2.9 1 1 1 2 2 2 0 Phi29 scaffolding protein Fib_alpha PF08702.5 EME28404.1 - 9.7 6.3 16.1 23 5.1 8.5 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CASP_C PF08172.7 EME28405.1 - 9.2e-10 37.9 5.8 9.2e-10 37.9 4.0 5.1 2 1 1 4 4 4 1 CASP C terminal WEMBL PF05701.6 EME28405.1 - 0.0015 17.0 78.3 0.0043 15.5 7.2 3.2 1 1 2 3 3 3 2 Weak chloroplast movement under blue light DUF2730 PF10805.3 EME28405.1 - 0.0059 16.3 2.8 0.0059 16.3 2.0 6.2 6 1 1 7 7 7 4 Protein of unknown function (DUF2730) Swi3 PF07962.7 EME28405.1 - 0.091 12.4 0.1 0.091 12.4 0.1 3.8 3 2 1 4 4 4 0 Replication Fork Protection Component Swi3 CDC37_N PF03234.9 EME28405.1 - 5.7 7.2 72.7 0.033 14.5 17.6 5.1 3 1 3 6 6 6 0 Cdc37 N terminal kinase binding ThiS PF02597.15 EME28405.1 - 9.2 6.7 8.1 0.99 9.8 0.4 3.4 2 2 1 3 3 3 0 ThiS family CASP_C PF08172.7 EME28406.1 - 1.3e-08 34.1 10.5 1.3e-08 34.1 7.3 4.9 2 1 2 4 4 4 1 CASP C terminal WEMBL PF05701.6 EME28406.1 - 0.0013 17.2 8.6 0.0013 17.2 5.9 4.5 1 1 1 3 3 3 1 Weak chloroplast movement under blue light DUF2730 PF10805.3 EME28406.1 - 0.0056 16.4 2.8 0.0056 16.4 1.9 6.5 6 1 1 7 7 7 4 Protein of unknown function (DUF2730) Swi3 PF07962.7 EME28406.1 - 0.028 14.0 4.5 0.09 12.4 0.1 3.6 2 1 1 3 3 3 0 Replication Fork Protection Component Swi3 Aldo_ket_red PF00248.16 EME28407.1 - 4.3e-72 242.3 0.0 5.3e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EME28408.1 - 3.6e-73 245.8 0.0 4.1e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cyanate_lyase PF02560.9 EME28409.1 - 1.5e-30 104.5 0.1 2.5e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain NOGCT PF08155.6 EME28410.1 - 4.4e-25 87.1 0.6 9.8e-25 86.0 0.4 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EME28410.1 - 2.7e-24 84.7 0.0 5.1e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EME28410.1 - 1.3e-16 60.5 0.0 3.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME28410.1 - 5.8e-08 32.1 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B FAA_hydrolase PF01557.13 EME28411.1 - 4e-51 173.5 0.0 5.4e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EME28411.1 - 1.1e-23 83.2 0.0 3.3e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cyclin_N PF00134.18 EME28412.1 - 1.5e-16 60.1 0.2 3.3e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EME28412.1 - 0.0046 16.7 0.2 0.06 13.1 0.0 2.4 3 0 0 3 3 3 1 Transcription factor TFIIB repeat Peptidase_M48 PF01435.13 EME28414.1 - 5.8e-37 127.4 0.2 8.7e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EME28414.1 - 0.16 11.6 1.1 0.61 9.8 0.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF955) ADK PF00406.17 EME28415.1 - 5.4e-61 204.8 0.0 8.6e-61 204.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EME28415.1 - 3.7e-13 48.8 0.0 7.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EME28415.1 - 2.6e-05 24.1 0.0 9.3e-05 22.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME28415.1 - 0.00085 20.1 0.0 0.0018 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EME28415.1 - 0.016 14.6 0.4 1.3 8.3 0.0 2.6 2 1 1 3 3 3 0 Thymidylate kinase CTP_transf_1 PF01148.15 EME28416.1 - 2.4e-06 27.4 4.8 4.2e-06 26.6 3.3 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family ATP_synt_H PF05493.8 EME28416.1 - 0.057 13.5 3.1 4.5 7.4 0.8 3.3 4 0 0 4 4 4 0 ATP synthase subunit H DUF1691 PF07950.6 EME28416.1 - 0.4 10.6 3.7 2 8.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1691) O-FucT PF10250.4 EME28417.1 - 0.077 12.0 0.2 0.17 10.9 0.1 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Mito_carr PF00153.22 EME28419.1 - 5.5e-67 221.5 3.9 3.7e-23 81.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EME28420.1 - 7.1e-21 73.2 1.0 6.5e-07 29.0 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.6 EME28420.1 - 0.0084 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EME28420.1 - 0.031 13.0 0.1 6.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like MFS_1 PF07690.11 EME28421.1 - 1e-26 93.5 29.5 3.2e-16 59.0 1.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME28421.1 - 2.1e-05 23.2 17.2 0.00034 19.3 0.3 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Med10 PF09748.4 EME28422.1 - 5.6e-14 52.0 1.7 9e-14 51.3 0.2 1.9 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex GST_N_2 PF13409.1 EME28422.1 - 2.9e-10 39.9 0.0 8.2e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME28422.1 - 1.6e-09 37.4 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME28422.1 - 1.5e-06 28.0 0.0 3.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME28422.1 - 0.00019 21.8 0.2 0.00068 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME28422.1 - 0.00028 21.0 0.0 0.00094 19.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AOX PF01786.12 EME28423.1 - 8.5e-31 106.9 1.0 1.2e-30 106.5 0.7 1.2 1 0 0 1 1 1 1 Alternative oxidase Complex1_LYR PF05347.10 EME28424.1 - 3.4e-06 26.7 0.8 9.1e-06 25.3 0.6 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME28424.1 - 5.4e-05 23.3 0.3 5.4e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 Complex1_LYR-like DUF2573 PF10835.3 EME28424.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Complex1_LYR_2 PF13233.1 EME28424.1 - 0.043 14.2 5.4 0.12 12.8 3.4 2.2 2 1 0 2 2 2 0 Complex1_LYR-like Complex1_LYR PF05347.10 EME28425.1 - 3.4e-06 26.7 0.8 9.1e-06 25.3 0.6 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME28425.1 - 5.4e-05 23.3 0.3 5.4e-05 23.3 0.2 1.8 2 0 0 2 2 2 1 Complex1_LYR-like DUF2573 PF10835.3 EME28425.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Complex1_LYR_2 PF13233.1 EME28425.1 - 0.043 14.2 5.4 0.12 12.8 3.4 2.2 2 1 0 2 2 2 0 Complex1_LYR-like UPF0054 PF02130.12 EME28426.1 - 3.2e-31 107.5 0.0 4.4e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Peptidase_M10 PF00413.19 EME28426.1 - 0.067 12.9 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Matrixin zf-C3HC4_2 PF13923.1 EME28429.1 - 4.4e-11 42.6 12.4 8.8e-11 41.6 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME28429.1 - 3.8e-10 39.2 8.4 7.1e-10 38.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME28429.1 - 1e-09 37.9 8.3 2.2e-09 36.7 5.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME28429.1 - 1.4e-09 37.6 13.8 2.7e-09 36.7 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME28429.1 - 2.8e-07 30.1 10.2 5.2e-07 29.2 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME28429.1 - 2e-05 24.1 4.3 2e-05 24.1 3.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME28429.1 - 0.00013 21.7 14.2 0.00013 21.7 9.9 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME28429.1 - 0.009 16.1 9.9 0.015 15.3 6.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Cortexin PF11057.3 EME28429.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Cortexin of kidney zf-Apc11 PF12861.2 EME28429.1 - 0.024 14.4 4.9 0.036 13.9 3.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EME28429.1 - 0.033 13.9 6.8 0.05 13.3 4.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U-box PF04564.10 EME28429.1 - 0.047 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.1 EME28429.1 - 0.59 9.9 4.7 0.97 9.2 3.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EME28429.1 - 0.81 9.2 10.6 3.7 7.1 6.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 LIM PF00412.17 EME28429.1 - 2.1 8.4 8.0 22 5.1 0.0 2.3 2 0 0 2 2 2 0 LIM domain DUF2465 PF10239.4 EME28430.1 - 2.6e-11 43.2 3.2 2.8e-11 43.1 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) MFS_1 PF07690.11 EME28432.1 - 1.3e-16 60.2 25.0 1.8e-16 59.8 17.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily GrpE PF01025.14 EME28433.1 - 3.9e-46 156.6 7.1 6.8e-46 155.8 4.9 1.5 1 1 0 1 1 1 1 GrpE Dicty_REP PF05086.7 EME28433.1 - 1.3 6.7 7.7 1.6 6.3 5.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein KxDL PF10241.4 EME28434.1 - 0.035 13.9 0.8 9.1 6.2 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Terminase_2 PF03592.11 EME28434.1 - 0.1 12.9 3.5 7.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Terminase small subunit ORC5_C PF14630.1 EME28435.1 - 4.5e-25 88.6 3.1 6.1e-25 88.1 2.1 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PPK2 PF03976.9 EME28435.1 - 0.0022 17.3 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) AAA_16 PF13191.1 EME28435.1 - 0.0036 17.3 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EME28435.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Rrn6 PF10214.4 EME28436.1 - 0.2 9.6 0.0 0.29 9.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FHA PF00498.21 EME28437.1 - 3e-20 72.1 0.0 8.6e-20 70.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Med10 PF09748.4 EME28437.1 - 0.023 14.5 0.2 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex ATP-synt_Eps PF04627.8 EME28437.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain SnAC PF14619.1 EME28437.1 - 0.43 10.7 9.7 1.1 9.5 3.1 3.2 2 1 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex COX5B PF01215.14 EME28438.1 - 1.6e-13 50.4 0.2 2.7e-13 49.7 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 EME28438.1 - 0.0018 18.0 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain zf-H2C2_2 PF13465.1 EME28438.1 - 0.028 14.7 0.1 0.094 13.0 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger double domain DUF1528 PF07515.6 EME28438.1 - 0.037 14.0 0.3 0.87 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Rad50_zn_hook PF04423.9 EME28438.1 - 0.054 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc_ribbon_5 PF13719.1 EME28438.1 - 0.079 12.5 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TPR_1 PF00515.23 EME28439.1 - 6.6e-52 171.1 23.6 1.7e-09 36.9 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EME28439.1 - 5.2e-45 150.9 36.6 1.5e-14 53.3 0.1 6.6 3 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 EME28439.1 - 1e-44 146.8 22.6 1.5e-06 27.6 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 EME28439.1 - 1.8e-35 118.0 24.6 4.8e-05 22.8 0.2 10.4 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 EME28439.1 - 3.8e-34 114.0 20.0 6.4e-06 25.9 0.1 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EME28439.1 - 2.2e-28 97.9 26.9 1.6e-06 27.9 0.3 6.6 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 EME28439.1 - 1.4e-27 95.6 13.2 4.2e-10 40.0 0.0 6.0 4 2 1 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME28439.1 - 6.1e-26 88.5 12.1 0.00033 21.0 0.0 9.0 3 3 6 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME28439.1 - 2.5e-21 75.7 17.6 2.4e-06 27.7 0.2 6.3 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_9 PF13371.1 EME28439.1 - 1.3e-16 60.1 3.1 6.8e-05 22.6 0.1 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME28439.1 - 1.8e-15 56.2 23.3 0.013 15.9 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EME28439.1 - 3.4e-15 54.5 21.5 0.013 15.2 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_15 PF13429.1 EME28439.1 - 6e-14 51.7 6.9 8.4e-05 21.7 0.2 6.0 1 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EME28439.1 - 1.6e-10 40.9 15.8 0.0016 18.5 1.3 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EME28439.1 - 6.1e-05 22.8 14.0 0.68 9.8 0.0 7.0 7 1 0 7 7 6 1 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EME28439.1 - 9.8e-05 21.2 0.0 1.8 7.2 0.0 3.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 EME28439.1 - 0.00068 19.0 8.1 0.67 9.3 0.1 5.0 2 2 2 4 4 4 1 26S proteasome subunit RPN7 TPR_20 PF14561.1 EME28439.1 - 0.0011 19.0 0.4 1.6 8.8 0.0 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.7 EME28439.1 - 0.019 14.5 0.0 0.93 9.1 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.1 EME28439.1 - 0.023 14.5 4.4 0.18 11.7 0.1 4.2 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EME28439.1 - 0.11 12.4 11.2 7.8 6.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.12 EME28439.1 - 0.28 11.4 3.7 2.9 8.1 0.1 3.6 2 2 2 4 4 4 0 Bacterial transcriptional activator domain NOT2_3_5 PF04153.13 EME28440.1 - 1.2e-29 102.8 2.6 4.3e-29 101.0 1.8 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NOT2_3_5 PF04153.13 EME28441.1 - 1.3e-29 102.7 2.6 4.5e-29 101.0 1.8 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Methyltransf_26 PF13659.1 EME28442.1 - 3.8e-15 55.9 0.0 5.5e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EME28442.1 - 1.7e-12 47.0 0.0 2.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EME28442.1 - 4.1e-09 36.9 0.0 9.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28442.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EME28442.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 EME28442.1 - 2.7e-05 23.9 0.0 0.00015 21.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28442.1 - 9.9e-05 22.7 0.0 0.00041 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28442.1 - 0.00019 21.8 0.4 0.00071 20.0 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28442.1 - 0.00024 21.4 0.0 0.00048 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME28442.1 - 0.00029 20.0 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 EME28442.1 - 0.0058 15.7 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase TehB PF03848.9 EME28442.1 - 0.0075 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.13 EME28442.1 - 0.0088 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Cons_hypoth95 PF03602.10 EME28442.1 - 0.027 13.8 0.0 0.15 11.3 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical protein 95 NodS PF05401.6 EME28442.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EME28442.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Transcrip_reg PF01709.15 EME28443.1 - 4.2e-78 261.7 0.7 4.8e-78 261.5 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator ArfGap PF01412.13 EME28444.1 - 7e-34 116.1 0.0 1.7e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-Nse PF11789.3 EME28445.1 - 3.2e-13 48.9 3.5 6.5e-13 47.9 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EME28445.1 - 0.00019 21.0 5.2 0.0002 21.0 2.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 EME28445.1 - 0.0013 18.1 4.1 0.0031 17.0 2.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rtf2 PF04641.7 EME28445.1 - 0.01 15.0 0.3 0.01 15.0 0.2 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger MethyltransfD12 PF02086.10 EME28445.1 - 0.04 13.3 1.1 0.072 12.5 0.8 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Sec23_helical PF04815.10 EME28445.1 - 0.041 13.3 0.1 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain zf-C3HC4 PF00097.20 EME28445.1 - 0.097 12.3 2.5 0.21 11.2 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EME28445.1 - 0.099 12.6 0.1 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 U-box domain SRA1 PF07304.6 EME28445.1 - 0.17 11.6 1.8 0.79 9.4 0.2 2.5 1 1 2 3 3 3 0 Steroid receptor RNA activator (SRA1) zf-RING_2 PF13639.1 EME28445.1 - 0.41 10.5 3.3 0.92 9.3 2.3 1.6 1 0 0 1 1 1 0 Ring finger domain Myb_DNA-binding PF00249.26 EME28446.1 - 2.8e-13 49.6 0.5 9.5e-13 47.9 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28446.1 - 0.0015 18.5 2.4 0.0037 17.3 0.3 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Brix PF04427.13 EME28447.1 - 2.1e-47 161.2 0.1 2.7e-47 160.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain UvsW PF11637.3 EME28447.1 - 0.039 13.6 1.8 0.075 12.7 1.2 1.4 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Imm12 PF15589.1 EME28447.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Immunity protein 12 CPSase_sm_chain PF00988.17 EME28451.1 - 8.2e-49 164.4 0.0 1.4e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EME28451.1 - 1.2e-38 132.4 0.1 2.2e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EME28451.1 - 7.6e-09 35.3 0.3 2.1e-06 27.3 0.1 2.3 1 1 0 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.19 EME28451.1 - 0.00027 20.4 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family FA_desaturase PF00487.19 EME28452.1 - 5.3e-31 107.9 25.0 8.4e-31 107.3 17.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Ctr PF04145.10 EME28452.1 - 0.028 14.4 0.2 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 Ctr copper transporter family BPD_transp_1 PF00528.17 EME28453.1 - 1.7e-32 112.4 32.0 7.3e-20 71.2 9.5 2.4 1 1 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component LysR_substrate PF03466.15 EME28454.1 - 1.1e-41 142.2 0.0 1.4e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.22 EME28454.1 - 2.7e-20 71.8 0.0 5.2e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.2 EME28454.1 - 8.6e-05 21.5 0.0 0.00035 19.5 0.0 1.9 1 1 0 1 1 1 1 PBP superfamily domain HTH_30 PF13556.1 EME28454.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GerE PF00196.14 EME28454.1 - 0.016 14.5 0.1 0.061 12.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family RA PF00788.18 EME28454.1 - 0.083 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Glyco_trans_1_3 PF13528.1 EME28454.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF848 PF05852.6 EME28454.1 - 0.098 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Fer4_NifH PF00142.13 EME28455.1 - 2.2e-101 338.6 0.0 2.5e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.18 EME28455.1 - 2.8e-18 66.0 0.0 3.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EME28455.1 - 7.9e-09 34.9 0.5 7.9e-09 34.9 0.4 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EME28455.1 - 1.3e-08 34.8 0.1 2.1e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EME28455.1 - 5e-05 22.5 0.1 9.6e-05 21.5 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EME28455.1 - 0.0057 16.2 0.0 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EME28455.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EME28455.1 - 0.013 14.2 0.1 0.025 13.3 0.1 1.4 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 EME28455.1 - 0.025 14.0 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME28455.1 - 0.028 14.4 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EME28455.1 - 0.085 12.2 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 EME28455.1 - 0.41 10.4 2.9 2.1 8.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EME28455.1 - 0.51 9.8 1.6 0.79 9.2 1.1 1.6 1 1 0 1 1 1 0 AAA domain Oxidored_nitro PF00148.14 EME28456.1 - 2.1e-38 132.0 0.0 2.4e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase SecA_DEAD PF07517.9 EME28457.1 - 2e-116 387.9 1.5 4.2e-116 386.8 1.1 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.8 EME28457.1 - 4.2e-53 180.2 6.9 4.2e-53 180.2 4.8 2.9 3 0 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.15 EME28457.1 - 5.5e-37 126.6 0.2 2.2e-36 124.6 0.1 2.1 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.24 EME28457.1 - 4.2e-06 26.3 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28457.1 - 0.022 14.6 2.3 1.2 9.1 0.0 3.2 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Phycobilisome PF00502.14 EME28458.1 - 1.3e-54 184.2 0.4 1.4e-54 184.0 0.3 1.0 1 0 0 1 1 1 1 Phycobilisome protein Phycobilisome PF00502.14 EME28459.1 - 1.7e-63 213.0 1.2 1.9e-63 212.9 0.8 1.0 1 0 0 1 1 1 1 Phycobilisome protein Glu_synthase PF01645.12 EME28460.1 - 1.4e-160 534.1 0.0 2.5e-160 533.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.9 EME28460.1 - 8.1e-112 373.1 0.3 6.4e-111 370.2 0.0 2.4 3 0 0 3 3 3 1 Glutamate synthase central domain GATase_2 PF00310.16 EME28460.1 - 1.3e-110 369.5 0.0 2.1e-110 368.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GXGXG PF01493.14 EME28460.1 - 2.3e-64 216.1 8.7 4.1e-64 215.3 6.0 1.3 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.13 EME28460.1 - 0.027 13.3 2.1 0.07 11.9 1.4 1.7 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GATase_6 PF13522.1 EME28460.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain ACCA PF03255.9 EME28461.1 - 1.5e-43 147.8 0.9 1.8e-43 147.5 0.1 1.5 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.17 EME28461.1 - 3.6e-15 55.2 0.0 4.1e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH PF00378.15 EME28461.1 - 0.00092 18.3 0.8 0.022 13.8 0.1 2.5 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family Cytochrom_C_asm PF01578.15 EME28462.1 - 3.9e-79 265.1 19.1 3.9e-79 265.1 13.2 1.9 2 0 0 2 2 2 1 Cytochrome C assembly protein PBS_linker_poly PF00427.16 EME28463.1 - 6e-47 158.5 0.6 8.3e-47 158.1 0.4 1.2 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide Phycobilisome PF00502.14 EME28464.1 - 2.6e-34 118.2 0.0 1.2e-18 67.3 0.0 2.0 1 1 1 2 2 2 2 Phycobilisome protein EppA_BapA PF07268.6 EME28464.1 - 0.14 11.8 2.0 0.63 9.7 0.8 2.0 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) Photo_RC PF00124.14 EME28465.1 - 3.9e-93 311.1 16.5 4.5e-93 310.9 11.4 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre protein ResB PF05140.9 EME28466.1 - 3.2e-84 283.1 9.4 4.3e-66 223.3 6.4 2.0 1 1 0 2 2 2 2 ResB-like family Archease PF01951.11 EME28466.1 - 0.14 12.1 1.2 0.82 9.6 0.1 2.2 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) DUF1313 PF07011.6 EME28466.1 - 3.1 7.5 7.6 3.2 7.4 0.6 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1313) ThiG PF05690.9 EME28467.1 - 3.7e-106 353.7 0.3 4.2e-106 353.5 0.2 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EME28467.1 - 0.0007 18.9 0.1 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 EME28467.1 - 0.00085 18.3 0.6 0.033 13.1 0.2 2.4 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EME28467.1 - 0.049 12.4 0.1 0.081 11.7 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IMPDH PF00478.20 EME28467.1 - 0.078 11.8 1.2 0.13 11.1 0.8 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Dus PF01207.12 EME28467.1 - 0.14 10.9 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Response_reg PF00072.19 EME28469.1 - 1.2e-31 108.9 0.0 1.4e-30 105.6 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.23 EME28469.1 - 3.4e-27 94.1 0.0 6e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF2264 PF10022.4 EME28469.1 - 0.18 10.4 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) PSII PF00421.14 EME28470.1 - 5.9e-214 710.5 7.4 5.9e-214 710.5 5.1 1.8 2 0 0 2 2 2 1 Photosystem II protein Photo_RC PF00124.14 EME28470.1 - 3.8e-78 262.0 18.3 8.3e-78 260.9 12.7 1.6 1 0 0 1 1 1 1 Photosynthetic reaction centre protein Atracotoxin PF05353.6 EME28470.1 - 0.29 11.0 1.0 0.9 9.4 0.7 1.8 1 0 0 1 1 1 0 Delta Atracotoxin Cpn60_TCP1 PF00118.19 EME28471.1 - 2.3e-125 418.9 19.6 2.6e-125 418.7 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF947 PF06102.7 EME28471.1 - 0.05 13.4 1.7 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF947) Cob_adeno_trans PF01923.13 EME28471.1 - 0.064 13.0 2.0 0.16 11.7 0.2 2.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Psb28 PF03912.9 EME28472.1 - 2.2e-35 120.8 1.5 1e-27 96.1 0.5 2.0 1 1 1 2 2 2 2 Psb28 protein Response_reg PF00072.19 EME28473.1 - 1.2e-25 89.6 0.1 7.5e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.14 EME28473.1 - 3.9e-17 61.3 0.5 8.7e-17 60.1 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EME28473.1 - 2.3e-07 30.1 0.0 5.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.6 EME28473.1 - 0.00025 20.7 0.1 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.1 EME28473.1 - 0.0013 18.6 0.2 0.0042 17.0 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EME28473.1 - 0.0023 17.5 0.1 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.1 EME28473.1 - 0.0092 15.3 0.2 0.026 13.9 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Spo0A_C PF08769.6 EME28473.1 - 0.024 14.5 0.2 0.096 12.5 0.0 2.0 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF1670 PF07900.6 EME28473.1 - 0.033 13.4 0.2 0.23 10.6 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1670) TrmB PF01978.14 EME28473.1 - 0.05 13.3 0.2 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.11 EME28473.1 - 0.065 12.5 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 EME28473.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 1 0 Winged helix-turn helix DUF2316 PF10078.4 EME28473.1 - 0.094 12.7 0.2 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_38 PF13936.1 EME28473.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_C PF08784.6 EME28473.1 - 0.16 12.4 0.1 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal HTH_11 PF08279.7 EME28473.1 - 0.2 11.3 1.7 0.33 10.6 0.0 2.3 3 0 0 3 3 2 0 HTH domain Cytochrom_B_N_2 PF13631.1 EME28474.1 - 4.2e-45 153.5 4.9 4.2e-45 153.5 3.4 1.5 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 EME28474.1 - 4.7e-16 58.8 0.8 4.7e-16 58.8 0.6 2.4 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD CAAD PF14159.1 EME28474.1 - 0.0046 16.5 1.6 0.34 10.5 0.2 3.5 3 0 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase YajC PF02699.10 EME28474.1 - 0.12 12.1 0.1 0.34 10.6 0.1 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_L12 PF00542.14 EME28475.1 - 4.1e-28 97.1 11.5 2.3e-27 94.7 2.7 3.0 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L11_N PF03946.9 EME28475.1 - 4.4e-27 93.3 0.7 5.9e-26 89.6 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L1 PF00687.16 EME28475.1 - 5e-26 91.4 0.4 1.2e-21 77.0 0.1 2.8 2 1 1 3 3 3 2 Ribosomal protein L1p/L10e family Ribosomal_L11 PF00298.14 EME28475.1 - 4.8e-22 77.8 0.4 1.5e-21 76.3 0.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ThiF PF00899.16 EME28476.1 - 1.3e-31 109.1 0.0 3.2e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EME28476.1 - 0.00062 19.8 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Meleagrin PF08189.6 EME28476.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family DnaB_C PF03796.10 EME28477.1 - 2.5e-109 364.1 0.0 6.7e-109 362.7 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.16 EME28477.1 - 2.1e-27 95.0 2.0 1.4e-26 92.3 0.4 2.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain Intein_splicing PF14890.1 EME28477.1 - 1.6e-13 50.2 9.8 6.2e-08 31.9 0.3 2.7 2 1 1 3 3 3 2 Intein splicing domain AAA_25 PF13481.1 EME28477.1 - 4.8e-13 48.9 0.0 9.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME28477.1 - 8.5e-06 25.0 0.6 3.4e-05 23.0 0.2 2.1 2 1 0 2 2 2 1 KaiC Rad51 PF08423.6 EME28477.1 - 0.0068 15.3 0.2 0.017 14.0 0.1 1.7 2 0 0 2 2 2 1 Rad51 AAA_2 PF07724.9 EME28478.1 - 1.4e-57 194.3 1.5 1.7e-55 187.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.15 EME28478.1 - 1e-33 115.0 9.0 2.4e-16 59.3 0.2 3.8 4 0 0 4 4 4 2 Clp amino terminal domain AAA PF00004.24 EME28478.1 - 1.2e-23 83.7 2.0 8.9e-13 48.5 0.0 3.4 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EME28478.1 - 4.3e-22 77.8 0.5 4.3e-22 77.8 0.3 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EME28478.1 - 3.2e-18 65.7 1.0 7.3e-12 45.1 0.0 4.3 3 2 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME28478.1 - 1.2e-14 54.6 0.9 5.5e-06 26.4 0.0 5.2 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EME28478.1 - 1.7e-10 41.1 4.7 2.9e-05 24.2 0.1 4.8 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EME28478.1 - 4.9e-09 35.8 0.0 7.2e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EME28478.1 - 9.5e-09 36.1 3.8 0.0029 18.4 0.1 3.9 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EME28478.1 - 1.1e-07 31.3 0.0 0.0037 16.6 0.0 3.1 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EME28478.1 - 3.1e-07 30.7 8.8 0.00021 21.5 0.1 3.6 4 1 0 4 4 2 2 AAA domain Zeta_toxin PF06414.7 EME28478.1 - 4.9e-06 25.7 0.4 0.0045 16.1 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EME28478.1 - 3.3e-05 24.0 0.0 0.56 10.4 0.0 3.0 2 0 0 2 2 2 2 RNA helicase DNA_pol3_delta2 PF13177.1 EME28478.1 - 3.9e-05 23.3 0.7 0.011 15.4 0.0 4.1 3 1 0 3 3 3 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EME28478.1 - 4.2e-05 22.8 0.1 0.35 9.9 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EME28478.1 - 6.8e-05 22.5 0.1 0.024 14.3 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EME28478.1 - 7.1e-05 22.4 0.0 0.11 12.3 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain UVR PF02151.14 EME28478.1 - 9.9e-05 21.7 5.8 0.00028 20.2 4.0 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif RuvB_N PF05496.7 EME28478.1 - 0.00012 21.1 0.3 0.84 8.6 0.0 3.9 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EME28478.1 - 0.00016 21.1 0.8 0.082 12.3 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EME28478.1 - 0.00017 21.2 0.1 0.13 11.8 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EME28478.1 - 0.00021 21.2 0.0 0.39 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME28478.1 - 0.00093 18.1 0.3 0.059 12.2 0.1 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EME28478.1 - 0.0018 17.5 0.0 2.1 7.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME28478.1 - 0.0019 18.5 0.0 0.0019 18.5 0.0 3.5 2 2 0 2 2 1 1 AAA domain CbiA PF01656.18 EME28478.1 - 0.0021 17.4 0.0 1.4 8.2 0.0 3.0 3 0 0 3 3 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EME28478.1 - 0.003 17.2 15.4 0.0084 15.8 0.1 5.2 5 1 0 6 6 6 1 Archaeal ATPase Torsin PF06309.6 EME28478.1 - 0.0051 16.6 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 1 Torsin VirE PF05272.6 EME28478.1 - 0.0075 15.7 0.0 1.2 8.5 0.0 3.2 3 0 0 3 3 3 1 Virulence-associated protein E ResIII PF04851.10 EME28478.1 - 0.0077 16.0 3.6 2.4 7.9 0.0 4.1 4 1 1 5 5 4 1 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EME28478.1 - 0.0086 15.6 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EME28478.1 - 0.0098 15.6 0.6 4.7 6.8 0.0 3.5 3 0 0 3 3 3 0 NTPase KTI12 PF08433.5 EME28478.1 - 0.012 14.8 0.3 1.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Flagellin_C PF00700.16 EME28478.1 - 0.017 15.2 0.7 0.089 12.9 0.5 2.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region AAA_33 PF13671.1 EME28478.1 - 0.02 14.7 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EME28478.1 - 0.024 14.1 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EME28478.1 - 0.029 13.8 3.9 3.8 6.8 0.3 4.1 3 2 1 4 4 4 0 AAA-like domain DUF2075 PF09848.4 EME28478.1 - 0.031 13.2 0.1 1.6 7.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EME28478.1 - 0.041 13.5 0.0 13 5.4 0.0 3.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EME28478.1 - 0.056 12.9 0.0 6.6 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TPP_enzyme_N PF02776.13 EME28479.1 - 4.5e-55 185.7 0.1 1.4e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME28479.1 - 5e-51 172.3 0.1 1.2e-49 167.8 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME28479.1 - 5e-46 155.8 0.0 9e-46 155.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EME28479.1 - 0.00073 19.1 0.2 0.004 16.6 0.1 1.9 1 1 1 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg AA_kinase PF00696.23 EME28480.1 - 2.7e-40 138.4 5.2 3.4e-40 138.1 3.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family Peptidase_M41 PF01434.13 EME28481.1 - 5.3e-81 271.1 0.0 7.6e-81 270.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME28481.1 - 2e-45 154.1 0.0 8.9e-45 152.1 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EME28481.1 - 2.2e-05 23.3 0.1 5.5e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EME28481.1 - 4.1e-05 23.0 1.6 0.01 15.2 0.4 2.4 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EME28481.1 - 4.7e-05 24.1 1.6 9.8e-05 23.1 0.0 2.4 3 1 0 3 3 1 1 AAA domain FtsH_ext PF06480.10 EME28481.1 - 5.7e-05 23.2 0.1 0.00035 20.7 0.0 2.4 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EME28481.1 - 0.00011 21.9 0.1 0.00043 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME28481.1 - 0.0003 20.9 0.8 0.083 13.0 0.1 3.4 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.7 EME28481.1 - 0.00087 18.3 0.0 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EME28481.1 - 0.0011 18.1 0.1 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EME28481.1 - 0.0013 18.7 0.5 0.01 15.8 0.1 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EME28481.1 - 0.003 17.4 0.1 0.011 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EME28481.1 - 0.0032 16.6 3.0 0.35 9.9 0.1 2.9 2 0 0 2 2 2 2 KaiC IstB_IS21 PF01695.12 EME28481.1 - 0.0041 16.5 0.0 0.0094 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EME28481.1 - 0.0043 16.9 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EME28481.1 - 0.0053 16.7 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME28481.1 - 0.0054 16.4 2.7 0.019 14.7 1.9 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EME28481.1 - 0.014 14.5 0.1 0.031 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EME28481.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EME28481.1 - 0.02 13.8 0.0 0.046 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EME28481.1 - 0.021 15.1 0.7 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME28481.1 - 0.087 12.2 0.2 0.38 10.1 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain CPT PF07931.7 EME28481.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Fe-ADH_2 PF13685.1 EME28481.1 - 0.12 11.7 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase PSII PF00421.14 EME28482.1 - 4.5e-207 687.8 7.6 5.1e-207 687.6 5.2 1.0 1 0 0 1 1 1 1 Photosystem II protein Fer2 PF00111.22 EME28483.1 - 1.9e-22 78.7 0.9 2.4e-22 78.4 0.6 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GTP_EFTU PF00009.22 EME28484.1 - 7.4e-62 208.1 0.0 1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME28484.1 - 2.1e-37 127.2 1.5 6.4e-37 125.6 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME28484.1 - 5.1e-21 74.5 5.3 1.1e-20 73.4 2.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EME28484.1 - 2.8e-08 33.2 1.6 5.8e-06 25.8 0.7 2.5 2 0 0 2 2 2 2 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EME28484.1 - 3.1e-06 27.1 0.0 8.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME28484.1 - 0.017 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Ribosomal_S7 PF00177.16 EME28485.1 - 1.7e-51 173.7 5.1 1.8e-51 173.5 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF2621 PF11084.3 EME28485.1 - 0.12 12.0 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Ribosom_S12_S23 PF00164.20 EME28486.1 - 4.9e-55 184.1 1.9 6.1e-55 183.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L31 PF01197.13 EME28486.1 - 3.2e-15 55.8 0.0 9.8e-15 54.3 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L31 Ribosomal_S9 PF00380.14 EME28487.1 - 1.3e-39 135.1 0.7 3.5e-39 133.7 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 EME28487.1 - 2.7e-24 85.6 0.5 6.1e-24 84.5 0.3 1.6 1 1 1 2 2 2 1 Ribosomal protein L13 Ribosomal_S11 PF00411.14 EME28488.1 - 1.2e-45 154.2 1.7 2.6e-45 153.0 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S13 PF00416.17 EME28488.1 - 4.1e-36 123.6 1.5 1.9e-35 121.4 0.8 2.4 2 0 0 2 2 2 1 Ribosomal protein S13/S18 RNA_pol_A_CTD PF03118.10 EME28488.1 - 5.7e-27 92.9 0.6 2.3e-26 90.9 0.4 2.1 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.19 EME28488.1 - 2.2e-21 74.7 0.1 5.2e-21 73.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.21 EME28488.1 - 3.8e-21 75.3 0.3 2.8e-20 72.5 0.0 2.6 1 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain HHH_5 PF14520.1 EME28488.1 - 1e-07 32.0 1.2 0.0001 22.3 0.0 3.9 4 1 0 4 4 4 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EME28488.1 - 0.0033 17.2 0.1 0.28 11.1 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix motif RNA_pol_L_2 PF13656.1 EME28488.1 - 0.0035 16.7 0.3 0.86 9.0 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Planc_extracel PF07595.7 EME28488.1 - 0.015 14.9 0.1 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Planctomycete extracellular SecY PF00344.15 EME28489.1 - 2.3e-78 263.5 45.8 2.2e-76 257.0 31.7 2.2 1 1 0 1 1 1 1 SecY translocase Ribosomal_S8 PF00410.14 EME28490.1 - 3.2e-43 146.6 1.0 5.8e-43 145.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S8 Ribosomal_L6 PF00347.18 EME28490.1 - 1.7e-32 111.7 5.9 8.2e-19 67.8 0.1 2.8 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S5 PF00333.15 EME28490.1 - 6.3e-24 83.5 7.2 1.4e-23 82.3 5.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EME28490.1 - 8.8e-23 79.3 1.5 1.7e-22 78.5 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_L18p PF00861.17 EME28490.1 - 4.8e-11 42.9 0.1 1.1e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L18p/L5e family A1_Propeptide PF07966.7 EME28490.1 - 0.32 10.8 1.7 0.44 10.3 0.3 1.9 2 0 0 2 2 2 0 A1 Propeptide Ribosomal_L14 PF00238.14 EME28491.1 - 3.3e-52 175.3 2.3 3.6e-52 175.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L16 PF00252.13 EME28492.1 - 3.1e-48 162.9 0.1 3.1e-48 162.9 0.1 2.0 3 0 0 3 3 3 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.15 EME28492.1 - 1.6e-31 108.3 3.2 1.6e-31 108.3 2.2 2.0 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EME28492.1 - 1.9e-13 49.7 2.4 5e-13 48.4 1.6 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EME28492.1 - 0.0038 16.8 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EME28492.1 - 0.039 13.6 1.9 0.08 12.6 0.2 2.4 2 0 0 2 2 2 0 KH domain Ribosomal_L2_C PF03947.13 EME28493.1 - 1.8e-60 202.4 0.2 3e-60 201.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EME28493.1 - 1.5e-33 114.5 4.8 1.9e-32 111.0 2.4 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L3 PF00297.17 EME28494.1 - 2.9e-36 125.2 2.1 6.9e-33 114.1 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Crystall_3 PF08964.5 EME28494.1 - 0.0074 15.9 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin HSP70 PF00012.15 EME28495.1 - 1.4e-271 901.7 17.5 1.7e-271 901.5 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME28495.1 - 6.8e-21 74.1 7.0 4.9e-18 64.8 1.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EME28495.1 - 5.6e-05 22.8 0.3 0.00031 20.4 0.2 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EME28495.1 - 7.6e-05 22.5 12.2 0.057 13.2 0.6 5.0 4 1 0 4 4 4 2 Cell division protein FtsA BcrAD_BadFG PF01869.15 EME28495.1 - 0.00028 20.2 0.0 0.16 11.2 0.0 2.9 1 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 EME28495.1 - 0.012 14.7 5.1 0.077 12.0 0.0 3.4 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase DUF615 PF04751.9 EME28495.1 - 0.68 9.5 9.0 0.46 10.1 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Oxidored_nitro PF00148.14 EME28496.1 - 7e-94 314.6 0.0 8.1e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PCP_red PF08369.5 EME28496.1 - 0.00018 21.2 0.1 0.00054 19.7 0.0 1.8 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Bac_DNA_binding PF00216.16 EME28497.1 - 3.6e-23 81.4 3.7 7.8e-23 80.3 2.5 1.7 1 1 0 1 1 1 1 Bacterial DNA-binding protein PP-binding PF00550.20 EME28497.1 - 3.6e-15 55.9 0.4 5.5e-15 55.3 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EME28497.1 - 1.5e-05 24.9 0.4 4.5e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Acyl-carrier DUF4496 PF14908.1 EME28497.1 - 0.00039 20.3 0.1 0.00082 19.2 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4496) Ribosomal_L50 PF10501.4 EME28497.1 - 0.0015 18.5 0.3 0.0029 17.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S MtrH PF02007.13 EME28497.1 - 0.025 13.5 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit DUF1493 PF07377.7 EME28497.1 - 0.075 13.1 2.5 0.086 12.9 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1493) TFIIA_gamma_N PF02268.11 EME28497.1 - 0.13 11.8 0.1 0.41 10.2 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain R3H PF01424.17 EME28498.1 - 5.8e-08 32.3 0.1 2.7e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 R3H domain AAA PF00004.24 EME28498.1 - 7.2e-07 29.4 0.1 2e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EME28498.1 - 2.2e-06 27.9 0.2 2.2e-06 27.9 0.1 2.7 2 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EME28498.1 - 3.6e-06 27.1 1.4 6.5e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME28498.1 - 1.1e-05 25.0 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EME28498.1 - 0.00023 20.9 0.1 0.00086 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME28498.1 - 0.00026 21.0 0.1 0.00056 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EME28498.1 - 0.00044 20.1 0.2 0.00044 20.1 0.2 2.5 1 1 1 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EME28498.1 - 0.00045 21.0 0.2 0.0022 18.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EME28498.1 - 0.00046 19.1 2.5 0.00084 18.3 1.7 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EME28498.1 - 0.00056 19.6 10.2 0.045 13.4 1.8 3.9 3 1 0 3 3 3 1 NTPase AAA_30 PF13604.1 EME28498.1 - 0.00091 18.8 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME28498.1 - 0.001 18.4 0.4 0.062 12.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EME28498.1 - 0.0012 18.2 1.4 0.0016 17.9 0.0 1.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 EME28498.1 - 0.0012 18.2 0.0 0.0028 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.4 EME28498.1 - 0.0024 16.5 0.1 0.0039 15.8 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EME28498.1 - 0.0024 17.5 0.2 0.029 14.0 0.0 2.5 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 EME28498.1 - 0.0033 16.6 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EME28498.1 - 0.0036 16.9 0.1 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME28498.1 - 0.0046 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EME28498.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EME28498.1 - 0.0064 16.3 2.2 0.062 13.1 0.0 3.2 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 EME28498.1 - 0.011 14.5 0.1 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein KdpD PF02702.12 EME28498.1 - 0.012 14.7 1.1 0.023 13.8 0.1 1.9 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain KTI12 PF08433.5 EME28498.1 - 0.013 14.6 1.6 0.043 13.0 0.0 2.3 2 1 1 3 3 3 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EME28498.1 - 0.013 15.6 0.0 0.053 13.6 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EME28498.1 - 0.013 14.9 0.4 0.036 13.5 0.0 1.9 2 1 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EME28498.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME28498.1 - 0.022 15.2 1.1 1.5 9.3 0.0 3.0 3 1 0 3 3 2 0 Miro-like protein Arch_ATPase PF01637.13 EME28498.1 - 0.027 14.1 0.1 0.027 14.1 0.1 2.6 2 2 0 2 2 2 0 Archaeal ATPase ArsA_ATPase PF02374.10 EME28498.1 - 0.027 13.5 0.0 0.078 12.0 0.0 1.7 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_11 PF13086.1 EME28498.1 - 0.039 13.5 5.6 0.14 11.7 3.4 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME28498.1 - 0.052 13.8 0.5 0.052 13.8 0.3 2.2 2 2 0 2 2 1 0 ABC transporter AAA_3 PF07726.6 EME28498.1 - 0.087 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EME28498.1 - 0.15 12.0 2.0 0.94 9.4 1.3 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase KaiC PF06745.8 EME28498.1 - 0.18 10.9 5.3 0.95 8.5 1.1 3.0 2 1 0 2 2 2 0 KaiC PsaA_PsaB PF00223.14 EME28499.1 - 1.3e-85 287.9 5.3 1.4e-85 287.7 3.7 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein PsaA_PsaB PF00223.14 EME28500.1 - 1.2e-261 869.7 27.0 1.4e-261 869.4 18.7 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein PsaA_PsaB PF00223.14 EME28501.1 - 0 1104.4 35.3 0 1104.2 24.5 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein GATase PF00117.23 EME28502.1 - 1.4e-26 93.1 0.0 1.7e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EME28502.1 - 3.3e-10 39.8 0.0 9.5e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EME28502.1 - 4.4e-08 32.8 0.0 5.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EME28502.1 - 5.8e-05 22.6 0.1 0.0041 16.6 0.1 2.5 2 1 0 2 2 2 1 Peptidase C26 GATase_5 PF13507.1 EME28502.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF1039 PF06287.6 EME28502.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) PsaD PF02531.11 EME28503.1 - 3.6e-72 240.0 0.1 4e-72 239.9 0.0 1.0 1 0 0 1 1 1 1 PsaD Rubrerythrin PF02915.12 EME28504.1 - 9.2e-24 84.3 0.1 1.9e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Rubrerythrin rve_3 PF13683.1 EME28504.1 - 0.0091 15.5 0.2 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain polyprenyl_synt PF00348.12 EME28505.1 - 1.8e-58 197.4 0.0 2.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase E1_dh PF00676.15 EME28506.1 - 5.9e-99 330.5 0.0 7e-99 330.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EME28506.1 - 7.8e-07 28.7 0.1 3.3e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EME28506.1 - 1.2e-05 24.3 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 EME28506.1 - 4.2e-05 22.5 0.0 6.1e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EME28507.1 - 4.2e-48 163.1 0.0 6.7e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME28507.1 - 6e-35 119.8 0.2 1.8e-34 118.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain TatC PF00902.13 EME28508.1 - 3e-43 147.7 33.5 4.4e-43 147.1 23.2 1.2 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Apocytochr_F_C PF01333.14 EME28508.1 - 0.0068 16.2 1.1 0.019 14.7 0.8 1.8 1 0 0 1 1 1 1 Apocytochrome F, C-terminal Ion_trans_N PF08412.5 EME28508.1 - 0.1 11.9 6.5 0.038 13.3 0.9 2.6 2 0 0 2 2 2 0 Ion transport protein N-terminal DUF1625 PF07787.7 EME28508.1 - 7.4 5.7 9.7 0.21 10.7 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) PBS_linker_poly PF00427.16 EME28509.1 - 7.2e-131 430.0 8.6 6.4e-46 155.2 0.2 3.4 3 0 0 3 3 3 3 Phycobilisome Linker polypeptide Phycobilisome PF00502.14 EME28509.1 - 2.3e-23 82.6 0.9 3.6e-13 49.5 0.0 3.2 3 1 1 4 4 4 2 Phycobilisome protein PSD1 PF07587.6 EME28509.1 - 0.0014 18.0 2.8 1.5 8.1 0.0 4.1 3 1 1 4 4 4 2 Protein of unknown function (DUF1553) IQ-like PF15157.1 EME28509.1 - 0.021 15.0 0.1 1 9.6 0.0 2.6 2 0 0 2 2 2 0 IQ-like EF-hand_6 PF13405.1 EME28509.1 - 0.025 14.4 0.1 68 3.7 0.0 4.0 3 0 0 3 3 3 0 EF-hand domain Phycobilisome PF00502.14 EME28510.1 - 4.9e-93 309.0 1.8 1.6e-50 170.9 0.6 2.0 2 0 0 2 2 2 2 Phycobilisome protein DUF4165 PF13752.1 EME28510.1 - 0.03 14.0 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) ATP-synt_ab PF00006.20 EME28511.1 - 2.8e-63 213.2 0.0 4.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME28511.1 - 1.9e-26 92.7 0.1 4.6e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_DE_N PF02823.11 EME28511.1 - 1.5e-25 88.7 0.1 3e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab_N PF02874.18 EME28511.1 - 1.8e-25 88.9 0.8 6.3e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_DE PF00401.15 EME28511.1 - 2.5e-09 36.8 4.4 5e-09 35.9 3.0 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AAA_25 PF13481.1 EME28511.1 - 0.00033 20.1 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EME28511.1 - 0.00056 20.1 0.1 0.0045 17.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EME28511.1 - 0.0012 18.6 0.2 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase KaiC PF06745.8 EME28511.1 - 0.0023 17.0 0.2 0.009 15.1 0.1 2.0 2 0 0 2 2 2 1 KaiC DUF258 PF03193.11 EME28511.1 - 0.014 14.6 0.1 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EME28511.1 - 0.019 14.6 1.1 2.5 7.7 0.1 3.8 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EME28511.1 - 0.023 15.0 0.5 0.071 13.4 0.0 2.0 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EME28511.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EME28511.1 - 0.097 12.6 0.4 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EME28511.1 - 0.23 11.0 2.0 0.24 11.0 0.1 1.9 3 0 0 3 3 3 0 NACHT domain PhdYeFM_antitox PF02604.14 EME28511.1 - 0.28 10.8 4.4 0.087 12.4 0.7 1.9 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system TPR_11 PF13414.1 EME28512.1 - 2.2e-18 65.6 18.6 1.4e-11 43.8 5.3 3.1 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EME28512.1 - 2.2e-17 61.8 15.5 2.9e-08 32.9 0.7 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME28512.1 - 1e-13 50.0 15.2 6.7e-07 28.7 0.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME28512.1 - 1.4e-10 40.9 15.3 2.5e-09 36.9 4.1 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME28512.1 - 1.7e-09 36.7 9.8 0.00026 20.5 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME28512.1 - 2.3e-09 36.3 16.3 4.2e-06 26.1 0.8 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat MIT PF04212.13 EME28512.1 - 2e-06 27.5 15.5 0.028 14.3 1.3 3.4 2 1 1 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EME28512.1 - 5.2e-06 26.6 1.6 0.052 14.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME28512.1 - 1.3e-05 25.0 7.6 0.0095 16.0 0.5 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EME28512.1 - 1.4e-05 24.8 8.4 0.019 14.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME28512.1 - 7.7e-05 23.2 10.1 0.003 18.1 2.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME28512.1 - 0.00046 20.4 5.3 0.11 13.0 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 EME28512.1 - 0.00071 20.1 9.6 0.19 12.3 0.1 4.3 3 2 2 5 5 5 2 Sel1 repeat DUF2225 PF09986.4 EME28512.1 - 0.016 14.7 1.8 0.016 14.7 1.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Apc3 PF12895.2 EME28512.1 - 0.017 15.2 12.0 0.017 15.2 4.4 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP-synt_DE PF00401.15 EME28512.1 - 0.025 14.4 0.6 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Cohesin_load PF10345.4 EME28512.1 - 0.059 11.5 4.6 0.71 8.0 3.2 2.0 1 1 0 1 1 1 0 Cohesin loading factor DUF3808 PF10300.4 EME28512.1 - 0.07 11.6 2.6 0.088 11.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) BRO1 PF03097.13 EME28512.1 - 0.093 11.4 9.5 0.15 10.7 4.8 2.5 1 1 1 2 2 2 0 BRO1-like domain Fis1_TPR_C PF14853.1 EME28512.1 - 0.14 12.0 6.3 0.21 11.5 0.4 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EME28512.1 - 0.2 12.0 9.2 0.9 9.9 2.9 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EME28512.1 - 0.41 10.2 3.2 0.69 9.4 0.6 2.3 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 GTP_EFTU PF00009.22 EME28513.1 - 1.1e-24 86.8 8.2 2.7e-24 85.6 3.4 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EME28513.1 - 1.7e-21 76.1 11.8 1.7e-21 76.1 8.1 2.8 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EME28513.1 - 9.8e-11 41.6 0.7 9.8e-11 41.6 0.5 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase IF2_N PF04760.10 EME28513.1 - 8.6e-10 38.1 1.3 4.2e-09 35.9 0.9 2.4 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.17 EME28513.1 - 1.8e-08 33.9 0.2 1.8e-08 33.9 0.2 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EME28513.1 - 1.8e-08 34.8 0.9 1.8e-08 34.8 0.6 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EME28513.1 - 2e-07 30.9 0.8 0.00049 19.9 0.0 3.8 4 0 0 4 4 4 2 Dynamin family PduV-EutP PF10662.4 EME28513.1 - 0.00012 21.5 2.6 0.00076 18.9 1.8 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EME28513.1 - 0.00084 19.0 0.3 0.0041 16.8 0.2 2.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EME28513.1 - 0.0021 17.2 0.5 0.0057 15.8 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME28513.1 - 0.016 15.3 0.2 0.045 13.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME28513.1 - 0.15 11.9 0.0 0.59 10.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_pol_Rpb2_6 PF00562.23 EME28514.1 - 1e-153 511.7 4.8 1.6e-153 511.0 0.0 3.4 3 2 0 3 3 3 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb1_1 PF04997.7 EME28514.1 - 5.2e-79 265.9 1.0 5.2e-79 265.9 0.7 4.1 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EME28514.1 - 6.2e-49 166.1 4.5 1.3e-48 165.1 0.0 3.7 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.12 EME28514.1 - 9e-42 143.2 30.0 2.3e-40 138.6 7.6 5.1 4 2 0 5 5 5 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb2_1 PF04563.10 EME28514.1 - 2.6e-37 127.7 2.2 2.6e-37 127.7 1.5 2.4 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EME28514.1 - 1.4e-36 125.7 4.3 5.1e-36 123.8 3.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EME28514.1 - 4e-28 96.9 0.0 1.2e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EME28514.1 - 3.6e-27 94.4 0.0 1.4e-26 92.5 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb1_3 PF04983.13 EME28514.1 - 1.6e-22 79.9 0.6 1.6e-22 79.9 0.4 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb2_45 PF10385.4 EME28514.1 - 1.4e-17 63.1 2.6 1.3e-16 60.1 0.2 3.7 4 0 0 4 4 4 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb1_4 PF05000.12 EME28514.1 - 3.7e-16 58.7 0.0 1.8e-15 56.6 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.17 EME28514.1 - 9e-08 32.0 4.2 0.42 10.7 0.0 6.4 5 2 2 7 7 6 2 Peptidase family M23 Biotin_lipoyl_2 PF13533.1 EME28514.1 - 0.00015 21.3 2.9 6.7 6.4 0.1 5.0 4 0 0 4 4 4 2 Biotin-lipoyl like RnfC_N PF13375.1 EME28514.1 - 0.0085 15.7 1.3 1.6 8.4 0.0 4.1 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EME28514.1 - 1.6 8.4 9.3 15 5.2 0.0 6.0 7 0 0 7 7 7 0 Biotin-requiring enzyme Ribosomal_S2 PF00318.15 EME28515.1 - 3.7e-70 235.4 0.2 5e-70 234.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 ATP-synt_A PF00119.15 EME28516.1 - 8.7e-56 188.8 11.8 1.3e-55 188.2 8.2 1.2 1 0 0 1 1 1 1 ATP synthase A chain EF_TS PF00889.14 EME28516.1 - 3.6e-32 111.5 4.2 6.6e-21 74.6 1.4 2.2 1 1 1 2 2 2 2 Elongation factor TS UBA PF00627.26 EME28516.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain ATP-synt_C PF00137.16 EME28517.1 - 9.8e-23 79.8 10.6 1.1e-22 79.6 7.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_ab PF00006.20 EME28518.1 - 2.9e-73 245.9 0.3 2.9e-73 245.9 0.2 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_B PF00430.13 EME28518.1 - 6.1e-63 210.4 40.9 1.1e-33 115.8 12.2 4.0 4 0 0 4 4 4 2 ATP synthase B/B' CF(0) OSCP PF00213.13 EME28518.1 - 1.2e-42 145.6 1.5 1.2e-42 145.6 1.0 3.1 3 1 0 3 3 3 1 ATP synthase delta (OSCP) subunit ATP-synt_ab_C PF00306.22 EME28518.1 - 5.1e-23 81.7 1.2 5.1e-23 81.7 0.8 4.2 3 2 0 3 3 3 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME28518.1 - 5.5e-19 68.1 3.0 1.5e-18 66.7 2.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EME28518.1 - 7e-07 29.0 1.5 5.8e-06 26.1 0.4 2.8 1 1 1 2 2 2 1 HAS barrel domain UPF0051 PF01458.12 EME28519.1 - 1.7e-63 214.1 2.1 2.4e-63 213.6 1.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.22 EME28519.1 - 3.4e-09 37.1 2.0 0.00076 19.7 0.0 2.8 2 1 1 3 3 3 2 ABC transporter SMC_N PF02463.14 EME28519.1 - 0.0097 15.1 6.9 0.16 11.1 4.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Phage_T4_Gp30_7 PF06919.6 EME28519.1 - 0.034 14.1 0.2 7.8 6.5 0.0 2.9 1 1 1 2 2 2 0 Phage Gp30.7 protein MutS_V PF00488.16 EME28519.1 - 0.042 13.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain V UPF0181 PF03701.9 EME28519.1 - 0.12 11.7 0.3 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) NmrA PF05368.8 EME28520.1 - 1.5e-27 96.3 0.1 1.8e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME28520.1 - 2.1e-23 83.2 0.0 3.4e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME28520.1 - 2e-08 33.3 0.1 3e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME28520.1 - 5.3e-07 29.3 0.0 6.7e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EME28520.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.13 EME28520.1 - 0.072 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EME28520.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 EME28520.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain CemA PF03040.9 EME28521.1 - 2.1e-100 335.0 6.2 2.5e-100 334.8 4.3 1.1 1 0 0 1 1 1 1 CemA family VMA21 PF09446.5 EME28521.1 - 3 7.8 7.9 8 6.4 0.5 3.1 3 0 0 3 3 3 0 VMA21-like domain PsaL PF02605.10 EME28522.1 - 3.6e-44 149.9 3.9 1.6e-36 125.1 1.2 2.1 1 1 1 2 2 2 2 Photosystem I reaction centre subunit XI AA_permease_2 PF13520.1 EME28522.1 - 0.015 13.8 0.7 0.017 13.6 0.5 1.1 1 0 0 1 1 1 0 Amino acid permease YtxH PF12732.2 EME28522.1 - 8.5 6.8 6.5 21 5.5 4.5 1.6 1 0 0 1 1 1 0 YtxH-like protein Ycf4 PF02392.11 EME28523.1 - 2.3e-66 222.5 1.7 2.7e-66 222.3 1.2 1.0 1 0 0 1 1 1 1 Ycf4 Trp_syntA PF00290.15 EME28524.1 - 4.5e-83 277.7 0.3 4.9e-83 277.6 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.16 EME28524.1 - 6.8e-05 22.2 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EME28524.1 - 0.00098 18.2 0.1 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EME28524.1 - 0.011 15.0 0.3 0.023 13.9 0.0 1.6 2 0 0 2 2 2 0 PcrB family Ribul_P_3_epim PF00834.14 EME28524.1 - 0.016 14.3 0.1 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Peripla_BP_1 PF00532.16 EME28524.1 - 0.055 12.6 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family UPF0081 PF03652.10 EME28524.1 - 0.086 12.9 0.0 5.4 7.1 0.0 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0081) PSI_PsaF PF02507.10 EME28525.1 - 2.9e-76 254.9 0.0 3.3e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III Fzo_mitofusin PF04799.8 EME28525.1 - 0.039 13.3 0.2 0.057 12.7 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Phycobilisome PF00502.14 EME28526.1 - 3.1e-48 163.5 0.0 3.5e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Phycobilisome protein Cytochrom_C550 PF14495.1 EME28527.1 - 5e-69 230.0 1.7 3.3e-59 198.2 0.0 3.2 1 1 2 3 3 3 3 Cytochrome c-550 domain Cytochrome_CBB3 PF13442.1 EME28527.1 - 6.1e-25 87.1 0.1 4.5e-16 58.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Carboxyl_trans PF01039.17 EME28527.1 - 8.8e-20 70.5 0.1 1.3e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain Cytochrom_C PF00034.16 EME28527.1 - 4e-19 69.2 0.0 2.7e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome c Cytochrom_C1 PF02167.10 EME28527.1 - 0.00021 21.0 0.0 0.29 10.7 0.0 2.5 2 0 0 2 2 2 2 Cytochrome C1 family Cytochrome_C7 PF14522.1 EME28527.1 - 0.0012 18.4 0.3 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c7 Cytochrome_C554 PF13435.1 EME28527.1 - 0.0047 16.9 0.2 3.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c554 and c-prime DUF1111 PF06537.6 EME28527.1 - 0.023 12.9 0.3 0.68 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1111) Haem_bd PF14376.1 EME28527.1 - 0.026 14.2 0.8 3.3 7.4 0.0 2.8 2 1 1 3 3 3 0 Haem-binding domain Cytochrom_c3_2 PF14537.1 EME28527.1 - 0.046 14.0 0.3 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c3 Dehyd-heme_bind PF09098.5 EME28527.1 - 0.12 11.7 0.3 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding ABC_tran PF00005.22 EME28528.1 - 6.7e-32 110.6 0.0 9.8e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME28528.1 - 9.3e-10 38.9 8.2 2.8e-07 30.8 5.7 2.2 1 1 0 1 1 1 1 AAA domain BCA_ABC_TP_C PF12399.3 EME28528.1 - 0.0024 17.4 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.1 EME28528.1 - 0.0067 16.7 6.3 0.015 15.6 4.4 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EME28528.1 - 0.025 13.8 0.5 0.19 10.8 0.3 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EME28528.1 - 0.033 14.4 0.3 0.062 13.4 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EME28528.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ALS_ss_C PF10369.4 EME28529.1 - 1.2e-27 95.4 0.4 2.3e-27 94.5 0.1 1.6 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.1 EME28529.1 - 2.2e-19 69.0 0.2 5.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 EME28529.1 - 5.3e-12 44.9 0.2 1.9e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.1 EME28529.1 - 0.00015 22.0 0.5 0.00031 21.0 0.3 1.6 1 0 0 1 1 1 1 ACT domain AAA PF00004.24 EME28530.1 - 9.7e-09 35.5 0.6 5.3e-08 33.1 0.0 2.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME28530.1 - 0.0042 17.2 2.9 0.077 13.1 0.0 3.0 3 2 0 3 3 3 1 AAA domain DUF3945 PF13101.1 EME28530.1 - 0.048 12.9 0.1 0.099 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) HTH_45 PF14947.1 EME28530.1 - 0.073 12.8 1.7 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix RuBisCO_large PF00016.15 EME28531.1 - 2.8e-164 545.3 0.4 3.5e-164 545.0 0.3 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.11 EME28531.1 - 3.3e-66 220.7 0.3 6.9e-66 219.6 0.1 1.6 2 0 0 2 2 2 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain Retinal PF15449.1 EME28534.1 - 0.033 11.8 2.5 0.035 11.7 1.7 1.1 1 0 0 1 1 1 0 Retinal protein Thioredox_DsbH PF03190.10 EME28534.1 - 0.077 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF3899 PF13038.1 EME28536.1 - 0.035 14.2 0.3 0.94 9.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Arch_ATPase PF01637.13 EME28537.1 - 0.0001 22.0 0.0 0.00075 19.2 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase Glycolytic PF00274.14 EME28538.1 - 3e-32 111.3 0.0 3.2e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF1517 PF07466.6 EME28539.1 - 3.4e-60 203.5 0.5 4.5e-60 203.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) ATP12 PF07542.6 EME28539.1 - 3.3e-29 101.3 0.0 6.1e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Cellulose_synt PF03552.9 EME28539.1 - 0.00069 18.0 0.0 0.00099 17.5 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase Pox_A_type_inc PF04508.7 EME28540.1 - 0.0094 15.6 0.2 0.0094 15.6 0.2 4.7 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat DUF3877 PF12993.2 EME28540.1 - 0.027 14.0 3.0 0.44 10.0 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Mannitol_dh PF01232.18 EME28540.1 - 0.15 11.9 5.2 0.17 11.8 1.9 2.2 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain DUF4449 PF14613.1 EME28540.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4449) DUF489 PF04356.7 EME28540.1 - 0.31 10.6 13.9 0.25 10.9 1.5 2.7 1 1 0 3 3 3 0 Protein of unknown function (DUF489) T2SF PF00482.18 EME28540.1 - 0.32 10.8 1.8 0.79 9.6 0.3 2.3 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein F SAS4 PF15460.1 EME28540.1 - 0.42 10.5 0.1 0.42 10.5 0.0 3.5 1 1 2 3 3 3 0 Something about silencing, SAS, complex subunit 4 RPW8 PF05659.6 EME28540.1 - 0.61 9.6 8.4 0.075 12.5 1.1 2.8 2 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2400 PF09674.5 EME28540.1 - 1.5 8.4 11.2 3.2 7.3 1.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) WXG100 PF06013.7 EME28540.1 - 2.7 8.0 7.7 11 6.1 0.0 3.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG ACCA PF03255.9 EME28540.1 - 3.4 7.2 12.2 2.6 7.5 0.5 3.8 2 1 1 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc7 PF08317.6 EME28540.1 - 3.4 6.2 30.4 0.49 8.9 8.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.7 EME28540.1 - 3.6 5.9 9.0 5 5.4 3.0 2.3 1 1 2 3 3 3 0 Fusaric acid resistance protein family PAP2 PF01569.16 EME28541.1 - 1.8e-07 30.8 4.6 2.4e-07 30.4 3.2 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EME28541.1 - 0.029 13.8 0.3 0.043 13.3 0.1 1.3 1 1 0 1 1 1 0 PAP2 superfamily Zw10 PF06248.8 EME28542.1 - 0.00082 17.6 2.3 0.00082 17.6 1.6 2.3 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 FliJ PF02050.11 EME28542.1 - 0.0084 16.1 2.6 0.024 14.6 1.8 1.8 1 0 0 1 1 1 1 Flagellar FliJ protein DUF2353 PF09789.4 EME28542.1 - 0.023 13.9 4.0 0.086 12.0 2.8 2.1 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Transposase_22 PF02994.9 EME28542.1 - 0.031 12.7 1.5 0.053 11.9 1.0 1.3 1 0 0 1 1 1 0 L1 transposable element GAS PF13851.1 EME28542.1 - 0.073 12.2 11.3 0.0085 15.3 3.8 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FliT PF05400.8 EME28542.1 - 0.12 12.7 1.4 0.38 11.1 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliT DUF1242 PF06842.7 EME28543.1 - 7.7e-20 70.1 1.4 1.3e-19 69.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) AAA_18 PF13238.1 EME28544.1 - 9.7e-18 64.7 0.1 2e-17 63.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EME28544.1 - 2.6e-09 37.9 0.0 3.5e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EME28544.1 - 3.7e-05 23.9 0.0 0.00025 21.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EME28544.1 - 7e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME28544.1 - 0.00017 21.3 0.0 0.00044 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME28544.1 - 0.00018 21.4 0.1 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME28544.1 - 0.00046 19.3 0.0 0.00089 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EME28544.1 - 0.00074 19.5 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EME28544.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28544.1 - 0.0017 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EME28544.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase PduV-EutP PF10662.4 EME28544.1 - 0.0023 17.4 0.3 0.024 14.1 0.0 2.3 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 EME28544.1 - 0.0024 17.2 0.0 0.0052 16.2 0.0 1.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ADK PF00406.17 EME28544.1 - 0.0027 17.5 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_24 PF13479.1 EME28544.1 - 0.005 16.4 0.1 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EME28544.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EME28544.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EME28544.1 - 0.015 14.4 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 EME28544.1 - 0.024 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EME28544.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EME28544.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EME28544.1 - 0.028 14.1 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 NTPase MobB PF03205.9 EME28544.1 - 0.031 13.9 0.1 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.13 EME28544.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.7 EME28544.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 1 0 NACHT domain ABC_tran PF00005.22 EME28544.1 - 0.054 13.7 0.0 0.1 12.9 0.0 1.5 2 0 0 2 2 1 0 ABC transporter MCM PF00493.18 EME28544.1 - 0.058 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Sigma54_activat PF00158.21 EME28544.1 - 0.059 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EME28544.1 - 0.064 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EME28544.1 - 0.068 11.7 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.5 EME28544.1 - 0.069 12.3 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FeoB_N PF02421.13 EME28544.1 - 0.074 12.3 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B KaiC PF06745.8 EME28544.1 - 0.08 12.0 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 KaiC Miro PF08477.8 EME28544.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EME28544.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_3 PF07726.6 EME28544.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EME28544.1 - 0.13 11.0 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EME28544.1 - 0.13 12.3 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CPT PF07931.7 EME28544.1 - 0.14 11.8 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.7 EME28544.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus S1 PF00575.18 EME28545.1 - 1e-31 108.8 0.0 1.6e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.1 EME28545.1 - 1.4e-06 28.0 0.1 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 S1 domain TOBE_2 PF08402.5 EME28545.1 - 0.049 13.6 0.0 0.96 9.4 0.0 2.5 2 1 0 2 2 2 0 TOBE domain TRAM PF01938.15 EME28545.1 - 0.12 12.1 0.2 2.5 7.9 0.0 2.9 4 0 0 4 4 4 0 TRAM domain IlvC PF01450.14 EME28546.1 - 2e-23 82.8 0.0 2.8e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EME28546.1 - 3.4e-18 65.5 0.0 6.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain WD40 PF00400.27 EME28547.1 - 1.2e-57 189.8 28.0 8.8e-12 44.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME28547.1 - 0.0018 17.7 1.9 4.8 6.7 0.0 4.4 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EME28547.1 - 0.095 11.4 0.1 1.6 7.3 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like IKI3 PF04762.7 EME28547.1 - 0.15 9.8 2.3 0.095 10.4 0.2 1.7 2 0 0 2 2 2 0 IKI3 family ABC1 PF03109.11 EME28548.1 - 2e-29 102.0 0.0 6.7e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EME28548.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EME28548.1 - 0.015 14.4 0.0 0.058 12.5 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain CTDII PF01556.13 EME28549.1 - 1.7e-30 104.7 0.2 9.1e-23 79.9 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EME28549.1 - 2.4e-25 88.0 2.5 4.4e-25 87.2 1.3 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EME28549.1 - 2.2e-10 40.4 18.0 4.2e-10 39.5 12.4 1.5 1 0 0 1 1 1 1 DnaJ central domain ZZ PF00569.12 EME28550.1 - 1.5e-07 30.7 5.5 3e-07 29.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EME28550.1 - 2.7e-06 27.4 0.3 1.8e-05 24.7 0.0 2.5 2 1 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EME28550.1 - 6.9e-06 26.0 0.7 2.7e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28550.1 - 0.0016 18.4 0.1 0.0061 16.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Arfaptin PF06456.8 EME28550.1 - 0.019 14.3 1.1 0.036 13.4 0.8 1.4 1 0 0 1 1 1 0 Arfaptin-like domain Baculo_IE-1 PF05290.6 EME28550.1 - 0.043 13.5 1.5 0.086 12.5 1.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-B_box PF00643.19 EME28550.1 - 5.9 6.8 8.3 21 5.1 5.8 1.9 1 1 0 1 1 1 0 B-box zinc finger ZZ PF00569.12 EME28551.1 - 1.6e-07 30.7 5.5 3.1e-07 29.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EME28551.1 - 3e-06 27.2 0.3 1.9e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EME28551.1 - 9.3e-06 25.6 0.3 2.8e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28551.1 - 0.0021 18.1 0.0 0.0064 16.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.6 EME28551.1 - 0.045 13.4 1.5 0.09 12.5 1.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-B_box PF00643.19 EME28551.1 - 6.3 6.7 8.3 22 5.0 5.8 1.8 1 1 0 1 1 1 0 B-box zinc finger Mmp37 PF09139.6 EME28552.1 - 7.3e-79 265.1 0.0 1.6e-78 264.0 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 AAA PF00004.24 EME28554.1 - 1.2e-43 148.4 0.0 3.3e-43 147.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EME28554.1 - 2.6e-07 30.7 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EME28554.1 - 5.1e-07 29.5 0.0 1.8e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME28554.1 - 6.4e-06 26.2 0.1 3.1e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME28554.1 - 3.1e-05 24.1 0.1 0.00054 20.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME28554.1 - 4.6e-05 24.2 0.3 0.00026 21.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EME28554.1 - 0.00013 21.1 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME28554.1 - 0.00015 21.4 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EME28554.1 - 0.00048 19.5 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EME28554.1 - 0.0011 17.7 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EME28554.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2072 PF09845.4 EME28554.1 - 0.0016 18.3 0.9 0.0038 17.1 0.6 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) Zeta_toxin PF06414.7 EME28554.1 - 0.0038 16.3 0.0 0.0084 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EME28554.1 - 0.0041 17.0 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME28554.1 - 0.0044 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EME28554.1 - 0.0046 16.1 0.1 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME28554.1 - 0.0059 16.9 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EME28554.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EME28554.1 - 0.0063 15.7 0.0 0.081 12.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 EME28554.1 - 0.0092 15.1 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 KaiC RNA_helicase PF00910.17 EME28554.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.1 EME28554.1 - 0.015 14.8 0.2 0.036 13.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EME28554.1 - 0.022 14.1 0.1 0.069 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EME28554.1 - 0.022 14.2 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4618 PF15397.1 EME28554.1 - 0.027 13.8 0.6 0.053 12.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF815 PF05673.8 EME28554.1 - 0.028 13.3 0.0 0.063 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DASH_Dad2 PF08654.5 EME28554.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 Parvo_NS1 PF01057.12 EME28554.1 - 0.039 12.8 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EME28554.1 - 0.047 13.7 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EME28554.1 - 0.052 12.4 0.0 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Prefoldin_2 PF01920.15 EME28554.1 - 0.068 12.9 1.0 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit Tropomyosin_1 PF12718.2 EME28554.1 - 0.083 12.7 1.6 0.14 11.9 0.3 1.8 2 0 0 2 2 2 0 Tropomyosin like V-SNARE PF05008.10 EME28554.1 - 0.31 11.2 2.7 0.33 11.1 0.6 2.0 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus AAA_23 PF13476.1 EME28554.1 - 0.33 11.2 2.1 19 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF563 PF04577.9 EME28555.1 - 7.9e-22 78.1 0.3 2.1e-21 76.7 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF563) DUF2442 PF10387.4 EME28555.1 - 0.046 13.7 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Acetyltransf_1 PF00583.19 EME28556.1 - 3.7e-14 52.5 0.1 6.8e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME28556.1 - 2e-05 24.6 0.4 3.7e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME28556.1 - 0.00071 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EME28556.1 - 0.0014 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BRAP2 PF07576.7 EME28556.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 tRNA_m1G_MT PF01746.16 EME28557.1 - 4.1e-07 29.7 0.0 1.1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase JAB PF01398.16 EME28558.1 - 1.1e-29 102.4 0.1 1.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EME28558.1 - 4.6e-05 22.9 0.1 0.00024 20.6 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain OKR_DC_1 PF01276.15 EME28559.1 - 2e-64 217.7 0.0 2.7e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 EME28559.1 - 1.4e-12 47.2 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1_C PF03711.10 EME28559.1 - 6e-12 45.7 0.0 1.5e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_5 PF00266.14 EME28559.1 - 7.6e-09 34.7 0.0 1.8e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME28559.1 - 2.6e-07 30.0 0.0 3.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SLA_LP_auto_ag PF05889.8 EME28559.1 - 8.9e-06 24.4 0.1 1.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 EME28559.1 - 0.00018 20.7 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EME28559.1 - 0.0026 16.0 0.0 0.0037 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.11 EME28559.1 - 0.0062 15.2 0.0 0.0097 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Pyridoxal_deC PF00282.14 EME28559.1 - 0.041 12.3 0.0 0.065 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain SHMT PF00464.14 EME28559.1 - 0.059 11.7 0.0 0.09 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase MARVEL PF01284.18 EME28560.1 - 2.3e-07 30.7 12.9 6.3e-07 29.3 9.0 1.6 1 1 0 1 1 1 1 Membrane-associating domain ATG22 PF11700.3 EME28560.1 - 0.00018 20.1 3.2 0.00021 19.9 2.2 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like YfhO PF09586.5 EME28560.1 - 0.18 9.8 1.4 0.26 9.2 1.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4149 PF13664.1 EME28560.1 - 2.8 8.0 7.0 6.4 6.9 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF202 PF02656.10 EME28560.1 - 2.9 8.1 6.4 1.7e+02 2.4 4.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Syndecan PF01034.15 EME28560.1 - 4.1 7.1 6.0 7.1 6.3 1.6 2.7 2 1 1 3 3 3 0 Syndecan domain Frag1 PF10277.4 EME28560.1 - 4.5 6.6 13.8 1.3 8.4 1.6 2.2 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family TcpE PF12648.2 EME28560.1 - 4.9 7.3 9.1 1.6 8.9 2.7 2.4 2 1 1 3 3 3 0 TcpE family HrpB2 PF09487.5 EME28561.1 - 0.13 12.5 0.7 4.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) ABC_tran PF00005.22 EME28562.1 - 5.5e-25 88.2 0.0 1.5e-24 86.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EME28562.1 - 3.1e-09 36.3 0.0 0.00021 20.6 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME28562.1 - 3.5e-09 37.0 0.2 0.00073 19.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_13 PF13166.1 EME28562.1 - 0.00017 20.2 0.0 0.0012 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EME28562.1 - 0.00025 20.2 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EME28562.1 - 0.00042 19.7 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME28562.1 - 0.00048 19.9 0.3 0.011 15.6 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EME28562.1 - 0.0012 18.3 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EME28562.1 - 0.0022 17.8 0.0 0.0037 17.0 0.0 1.4 1 1 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 EME28562.1 - 0.0026 17.7 0.0 0.0051 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EME28562.1 - 0.012 15.9 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME28562.1 - 0.015 15.3 0.1 0.035 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EME28562.1 - 0.028 13.5 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EME28562.1 - 0.036 13.9 0.0 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME28562.1 - 0.064 12.9 0.0 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EME28562.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 EME28562.1 - 0.13 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 EME28562.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EME28563.1 - 2e-25 89.7 0.0 3.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME28563.1 - 3.2e-09 37.1 0.3 0.00068 19.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EME28563.1 - 7.2e-09 35.1 0.0 0.00017 20.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME28563.1 - 0.00011 21.6 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EME28563.1 - 0.00017 20.2 0.0 0.0011 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EME28563.1 - 0.00021 20.4 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EME28563.1 - 0.00032 20.1 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME28563.1 - 0.00043 20.1 0.2 0.0096 15.8 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EME28563.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EME28563.1 - 0.0026 17.5 0.0 0.0041 16.9 0.0 1.4 1 1 0 1 1 1 1 Dynamin family AAA_23 PF13476.1 EME28563.1 - 0.0092 16.3 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28563.1 - 0.013 15.6 0.1 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EME28563.1 - 0.016 14.3 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pox_A22 PF04848.8 EME28563.1 - 0.032 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A22 protein AAA_33 PF13671.1 EME28563.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME28563.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 EME28563.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EME28563.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EME28563.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B S4 PF01479.20 EME28564.1 - 2.9e-19 68.2 0.3 5.4e-19 67.3 0.2 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EME28564.1 - 0.063 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 S4 domain Methyltransf_23 PF13489.1 EME28565.1 - 4.1e-17 62.3 0.1 5.6e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28565.1 - 2e-11 44.2 0.0 4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28565.1 - 1.8e-10 41.1 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28565.1 - 1.7e-09 37.4 0.0 3.4e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28565.1 - 1.6e-08 35.0 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28565.1 - 7.5e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28565.1 - 1.8e-06 27.9 0.0 4.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME28565.1 - 9.6e-05 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EME28565.1 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EME28565.1 - 0.02 13.9 0.0 4.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.1 EME28565.1 - 0.034 14.9 0.0 0.1 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.12 EME28565.1 - 0.035 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Pox_MCEL PF03291.11 EME28565.1 - 0.044 12.6 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme HyaE PF07449.6 EME28565.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Methyltransf_23 PF13489.1 EME28566.1 - 1.3e-11 44.5 0.1 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME28566.1 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28566.1 - 3.3e-08 33.9 0.5 1.9e-06 28.2 0.2 2.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28566.1 - 3.3e-08 34.0 0.0 5.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28566.1 - 7e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28566.1 - 5.6e-05 23.1 0.1 9.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME28566.1 - 0.081 12.0 0.0 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Prenyltransf PF01255.14 EME28567.1 - 5e-46 156.6 0.0 6.5e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Hydrolase_6 PF13344.1 EME28568.1 - 1e-32 112.0 0.0 1.7e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME28568.1 - 6.5e-14 51.4 0.0 2.6e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EME28568.1 - 2.1e-12 47.8 0.0 3.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME28568.1 - 1.2e-06 28.8 0.1 0.066 13.4 0.0 3.0 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EME28568.1 - 0.00024 20.4 0.0 0.0054 16.0 0.0 2.3 1 1 1 2 2 2 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.9 EME28568.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EME28568.1 - 0.016 15.3 0.0 0.054 13.6 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cyc-maltodext_C PF10438.4 EME28568.1 - 0.084 12.9 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain zf-C3HC PF07967.8 EME28569.1 - 6e-15 55.1 4.8 5e-13 48.9 0.0 3.9 2 1 0 2 2 2 2 C3HC zinc finger-like DEAD PF00270.24 EME28570.1 - 1.5e-45 154.7 0.0 2.8e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28570.1 - 9.6e-10 38.1 0.0 3e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME28570.1 - 3.8e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME28570.1 - 4.5e-05 22.3 0.0 6.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.1 EME28570.1 - 0.017 14.6 0.0 0.36 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain Helicase_C PF00271.26 EME28571.1 - 6.7e-12 45.1 0.0 1.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2463 PF09591.5 EME28571.1 - 0.17 11.4 0.5 0.22 11.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Nop PF01798.13 EME28572.1 - 2.7e-60 202.0 1.0 5.4e-60 201.0 0.7 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EME28572.1 - 9.8e-28 95.7 0.1 1.8e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EME28572.1 - 4.7e-15 55.4 2.0 1.6e-14 53.8 1.4 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain NICE-3 PF07406.6 EME28572.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 NICE-3 protein DUF694 PF05107.7 EME28572.1 - 0.71 9.0 9.8 1.4 8.0 5.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF694) MGDG_synth PF06925.6 EME28573.1 - 5.3e-31 107.7 0.0 9.2e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.11 EME28573.1 - 3.8e-10 39.6 0.0 6.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.1 EME28573.1 - 8.7e-06 25.9 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.1 EME28573.1 - 0.0013 18.0 0.0 0.0089 15.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 1 MerR PF00376.18 EME28573.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Glycos_transf_1 PF00534.15 EME28573.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Aminotran_1_2 PF00155.16 EME28574.1 - 1.3e-61 208.6 0.0 1.6e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EME28574.1 - 4.6e-07 28.4 0.0 1.2e-06 27.0 0.0 1.6 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME28574.1 - 9.6e-07 28.1 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EME28574.1 - 1.5e-06 27.1 0.0 4.3e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME28574.1 - 9.1e-06 25.0 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C3HC4_2 PF13923.1 EME28574.1 - 2.5 8.2 5.9 4.8 7.3 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YGGT PF02325.12 EME28575.1 - 6.7e-21 74.0 6.0 9.1e-21 73.5 4.2 1.2 1 0 0 1 1 1 1 YGGT family Rad60-SLD PF11976.3 EME28576.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L11_N PF03946.9 EME28577.1 - 1.4e-26 91.6 0.2 2.5e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EME28577.1 - 9.6e-23 80.1 0.1 1.7e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4318 PF14201.1 EME28577.1 - 0.039 13.7 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) RWP-RK PF02042.10 EME28578.1 - 3.8e-22 77.8 0.2 6.5e-22 77.1 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF3585 PF12130.3 EME28578.1 - 0.0004 20.2 2.3 0.0022 17.8 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) DUF2205 PF10224.4 EME28578.1 - 0.028 13.9 1.6 0.052 13.1 0.0 2.3 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EME28578.1 - 0.078 13.3 3.9 2 8.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EME28578.1 - 0.091 12.7 1.3 3.3 7.7 0.0 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Microtub_assoc PF07989.6 EME28578.1 - 3.8 7.4 6.7 9.3 6.1 0.2 3.0 2 1 0 2 2 2 0 Microtubule associated DUF904 PF06005.7 EME28578.1 - 5.5 7.3 8.4 19 5.6 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EME28578.1 - 9.7 5.7 7.9 12 5.4 0.1 3.2 2 1 1 3 3 3 0 Septum formation initiator zf-ribbon_3 PF13248.1 EME28579.1 - 9e-05 21.5 4.4 0.11 11.6 0.2 2.9 3 0 0 3 3 3 2 zinc-ribbon domain DUF2614 PF11023.3 EME28579.1 - 0.00017 21.3 0.3 0.00032 20.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2614) DZR PF12773.2 EME28579.1 - 0.00088 19.0 1.9 0.0074 16.0 0.1 2.3 2 0 0 2 2 2 1 Double zinc ribbon Nudix_N_2 PF14803.1 EME28579.1 - 0.036 13.7 2.9 9.5 6.0 0.1 3.5 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_4 PF13717.1 EME28579.1 - 0.061 13.0 4.7 1.9 8.2 0.0 3.4 4 0 0 4 4 3 0 zinc-ribbon domain FYVE PF01363.16 EME28579.1 - 0.078 12.8 1.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF3487 PF11990.3 EME28579.1 - 0.11 11.9 1.5 0.17 11.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DNA_RNApol_7kD PF03604.8 EME28579.1 - 0.12 11.8 0.5 0.12 11.8 0.4 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbons_6 PF07191.7 EME28579.1 - 0.15 11.8 1.4 2.7 7.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons C1_1 PF00130.17 EME28579.1 - 0.18 11.5 1.3 0.54 10.0 0.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EME28579.1 - 0.23 11.1 2.3 0.66 9.6 0.2 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_recom PF13408.1 EME28579.1 - 0.39 11.0 4.2 24 5.2 0.3 3.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 EME28579.1 - 0.8 9.0 7.0 0.11 11.8 1.7 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.9 EME28579.1 - 1 9.3 4.9 1.3 9.0 0.5 2.9 2 2 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_5 PF13719.1 EME28579.1 - 1.4 8.5 9.4 4.6 6.9 1.8 3.4 3 1 1 4 4 4 0 zinc-ribbon domain HEAT PF02985.17 EME28580.1 - 2.9e-08 33.1 0.7 0.24 11.5 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EME28580.1 - 2.2e-07 31.0 7.9 4.9e-05 23.5 0.7 3.3 2 1 1 3 3 3 2 HEAT repeats RICTOR_V PF14668.1 EME28580.1 - 0.0096 15.8 0.2 0.06 13.2 0.0 2.5 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RTTN_N PF14726.1 EME28580.1 - 0.14 12.7 4.1 0.18 12.4 0.7 2.8 2 2 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Fes1 PF08609.5 EME28580.1 - 1.5 9.3 11.3 0.087 13.3 1.9 3.1 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 RIC1 PF07064.8 EME28581.1 - 3.2e-30 105.4 1.0 6.1e-30 104.5 0.7 1.4 1 0 0 1 1 1 1 RIC1 Elong-fact-P_C PF09285.6 EME28582.1 - 4.9e-27 93.0 2.2 4.9e-27 93.0 1.5 2.3 3 0 0 3 3 3 1 Elongation factor P, C-terminal EFP_N PF08207.7 EME28582.1 - 1.7e-26 91.8 0.6 6.1e-26 90.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 EME28582.1 - 6.6e-13 48.1 0.0 1.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain bZIP_1 PF00170.16 EME28583.1 - 0.00045 20.1 14.9 0.00045 20.1 10.3 3.0 3 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EME28583.1 - 0.016 15.0 15.8 0.016 15.0 11.0 2.6 2 1 0 2 2 2 0 Basic region leucine zipper HAUS6_N PF14661.1 EME28583.1 - 0.19 11.0 13.7 0.29 10.4 9.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TSC22 PF01166.13 EME28583.1 - 0.58 10.1 8.8 0.19 11.7 1.8 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family FlxA PF14282.1 EME28583.1 - 2.6 8.0 19.0 0.2 11.6 8.7 2.4 2 0 0 2 2 2 0 FlxA-like protein SOBP PF15279.1 EME28583.1 - 5.3 7.3 16.5 12 6.1 11.4 1.6 1 1 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.14 EME28583.1 - 7.3 4.3 7.2 8.5 4.0 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GATA PF00320.22 EME28584.1 - 3.6e-16 58.1 3.9 3.6e-16 58.1 2.7 2.1 2 0 0 2 2 2 1 GATA zinc finger ABC_membrane PF00664.18 EME28585.1 - 2.1e-50 171.6 11.2 2.1e-50 171.6 7.8 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EME28585.1 - 8.7e-34 116.7 0.0 1.6e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Steroid_dh PF02544.11 EME28585.1 - 1.7e-28 99.2 3.7 3.8e-28 98.1 2.5 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase AAA_21 PF13304.1 EME28585.1 - 2.8e-07 30.8 0.1 2.1e-05 24.6 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EME28585.1 - 1.7e-06 28.2 0.3 2.5e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EME28585.1 - 6.1e-06 25.6 0.1 0.0044 16.2 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME28585.1 - 8.1e-06 25.3 0.1 2.3e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME28585.1 - 2.5e-05 25.0 0.0 7e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EME28585.1 - 3.3e-05 23.9 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ubiquitin PF00240.18 EME28585.1 - 3.6e-05 23.0 1.0 0.0001 21.6 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EME28585.1 - 8.9e-05 22.6 1.2 0.00018 21.6 0.4 1.8 2 0 0 2 2 1 1 Ubiquitin-like domain DUF1295 PF06966.7 EME28585.1 - 0.00014 21.2 1.9 0.00014 21.2 1.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) AAA_29 PF13555.1 EME28585.1 - 0.00026 20.4 0.1 0.00066 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EME28585.1 - 0.00034 20.8 0.1 0.019 15.1 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PEMT PF04191.8 EME28585.1 - 0.00065 19.7 0.9 0.00065 19.7 0.6 2.6 3 0 0 3 3 2 1 Phospholipid methyltransferase AAA_30 PF13604.1 EME28585.1 - 0.0031 17.1 0.0 0.0086 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain UN_NPL4 PF11543.3 EME28585.1 - 0.0038 17.4 1.8 0.012 15.8 0.2 2.8 2 0 0 2 2 1 1 Nuclear pore localisation protein NPL4 ABC_ATPase PF09818.4 EME28585.1 - 0.006 15.2 0.2 0.015 13.8 0.0 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.9 EME28585.1 - 0.011 15.4 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EME28585.1 - 0.012 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME28585.1 - 0.044 13.6 0.6 0.22 11.4 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME28585.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EME28585.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME28585.1 - 0.056 12.8 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EME28585.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME28585.1 - 0.067 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 EME28586.1 - 2e-50 171.7 11.2 2e-50 171.7 7.8 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EME28586.1 - 8.4e-34 116.8 0.0 1.6e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Steroid_dh PF02544.11 EME28586.1 - 1.6e-28 99.3 3.7 3.7e-28 98.1 2.5 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase AAA_21 PF13304.1 EME28586.1 - 2.6e-07 30.8 0.0 2.1e-05 24.6 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EME28586.1 - 1.6e-06 28.2 0.3 2.4e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EME28586.1 - 5.9e-06 25.6 0.1 0.0043 16.3 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME28586.1 - 7.8e-06 25.4 0.1 2.3e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME28586.1 - 2.4e-05 25.1 0.0 6.8e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EME28586.1 - 3.2e-05 23.9 0.1 9.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ubiquitin PF00240.18 EME28586.1 - 3.5e-05 23.0 1.0 9.9e-05 21.6 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EME28586.1 - 8.7e-05 22.7 1.2 0.00018 21.6 0.4 1.8 2 0 0 2 2 1 1 Ubiquitin-like domain DUF1295 PF06966.7 EME28586.1 - 0.00014 21.2 2.0 0.00014 21.2 1.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) AAA_29 PF13555.1 EME28586.1 - 0.00025 20.4 0.1 0.00064 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EME28586.1 - 0.00033 20.8 0.1 0.018 15.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PEMT PF04191.8 EME28586.1 - 0.00063 19.8 0.9 0.00063 19.8 0.6 2.6 3 0 0 3 3 2 1 Phospholipid methyltransferase AAA_30 PF13604.1 EME28586.1 - 0.003 17.1 0.0 0.0083 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain UN_NPL4 PF11543.3 EME28586.1 - 0.0037 17.5 1.9 0.012 15.8 0.2 2.8 2 0 0 2 2 1 1 Nuclear pore localisation protein NPL4 ABC_ATPase PF09818.4 EME28586.1 - 0.0057 15.2 0.2 0.015 13.9 0.0 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.9 EME28586.1 - 0.01 15.5 0.1 0.099 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EME28586.1 - 0.012 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME28586.1 - 0.042 13.7 0.6 0.21 11.4 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME28586.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EME28586.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME28586.1 - 0.053 12.9 0.2 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EME28586.1 - 0.056 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME28586.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Spt5-NGN PF03439.8 EME28587.1 - 2.9e-22 78.2 0.0 6.8e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EME28587.1 - 1.7e-17 62.3 20.2 0.00078 19.0 0.3 7.1 7 0 0 7 7 7 6 KOW motif CTD PF12815.2 EME28587.1 - 4.4e-05 23.9 4.6 4.4e-05 23.9 3.2 1.7 2 0 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4438 PF14505.1 EME28587.1 - 0.0051 15.6 1.8 1.9 7.2 0.0 3.4 4 0 0 4 4 4 2 Domain of unknown function (DUF4438) DUF938 PF06080.7 EME28588.1 - 7.1e-51 172.6 0.0 8.5e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 EME28588.1 - 3.1e-06 27.5 0.0 5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28588.1 - 1.6e-05 25.3 0.0 2.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28588.1 - 3.7e-05 24.1 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28588.1 - 3.9e-05 23.9 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME28588.1 - 0.00091 18.6 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EME28588.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 EME28589.1 - 1.2e-48 164.8 0.0 1.4e-47 161.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28589.1 - 2.1e-25 88.3 0.1 4.8e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EME28589.1 - 0.0001 20.8 0.0 0.00017 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EME28589.1 - 0.0051 15.9 0.0 0.014 14.4 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Phage_integrase PF00589.17 EME28589.1 - 0.089 12.4 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Phage integrase family DUF3950 PF13132.1 EME28589.1 - 0.12 11.9 0.1 19 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) PPTA PF01239.17 EME28591.1 - 2e-11 42.6 16.0 0.00036 19.7 2.4 5.2 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat Ca_chan_IQ PF08763.6 EME28591.1 - 0.17 11.1 0.1 0.17 11.1 0.1 2.8 3 0 0 3 3 3 0 Voltage gated calcium channel IQ domain NUDIX PF00293.23 EME28592.1 - 2.6e-16 59.5 0.0 4.2e-16 58.8 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain TIG PF01833.19 EME28593.1 - 1.7e-16 60.0 0.1 3.1e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain ubiquitin PF00240.18 EME28593.1 - 0.00066 19.0 0.0 0.0043 16.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Bap31 PF05529.7 EME28596.1 - 5e-22 78.2 2.3 6.8e-22 77.8 1.6 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like GlutR_N PF05201.10 EME28597.1 - 8e-45 152.1 0.0 1.6e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 EME28597.1 - 1.2e-32 112.8 0.0 4e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 EME28597.1 - 8e-23 80.2 2.9 8.5e-23 80.2 0.8 2.0 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.12 EME28597.1 - 3.6e-08 33.7 0.0 2.4e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EME28597.1 - 2.5e-06 26.4 0.0 4.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.13 EME28597.1 - 0.0069 16.3 0.2 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 EME28597.1 - 0.023 14.9 0.0 0.068 13.4 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_L19e PF01280.15 EME28598.1 - 4.3e-64 214.7 10.7 4.3e-64 214.7 7.4 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e UvrD-helicase PF00580.16 EME28598.1 - 0.014 14.7 1.6 0.015 14.6 1.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Elongin_A PF06881.6 EME28598.1 - 2.3 8.6 8.2 8.6 6.7 5.7 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GNAT_acetyltr_2 PF13718.1 EME28599.1 - 2.1e-75 252.3 0.0 4e-75 251.4 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EME28599.1 - 1.5e-60 203.8 0.0 5e-60 202.1 0.0 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EME28599.1 - 7.4e-39 131.3 0.1 1.9e-38 130.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EME28599.1 - 2.4e-23 82.1 0.7 1.1e-22 79.9 0.5 2.2 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EME28599.1 - 0.00014 22.0 0.1 0.012 15.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain Acetyltransf_7 PF13508.1 EME28599.1 - 0.0021 18.1 0.0 0.0066 16.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.1 EME28599.1 - 0.09 12.7 0.9 16 5.4 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain TPR_MLP1_2 PF07926.7 EME28599.1 - 1.1 9.0 10.4 2.6 7.7 1.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WD40 PF00400.27 EME28600.1 - 0.0009 19.0 0.1 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Apc4 PF12896.2 EME28600.1 - 0.0058 15.9 5.5 0.0098 15.2 3.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ProRS-C_1 PF09180.6 EME28601.1 - 1.3e-19 69.8 0.2 3.5e-19 68.5 0.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EME28601.1 - 9.3e-16 57.8 0.1 1.6e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME28601.1 - 2.1e-13 50.0 1.4 7.3e-13 48.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain Herpes_UL49_1 PF03117.9 EME28601.1 - 0.0071 15.4 0.0 0.028 13.5 0.0 1.8 2 0 0 2 2 2 1 UL49 family DUF3411 PF11891.3 EME28602.1 - 1.5e-51 174.6 0.0 2.2e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3411) Tic22 PF04278.7 EME28603.1 - 3.6e-37 128.1 0.1 4.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Tic22-like family Adap_comp_sub PF00928.16 EME28604.1 - 1.9e-78 263.1 0.0 2.4e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME28604.1 - 3.9e-07 29.8 1.4 5.8e-07 29.3 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 EME28605.1 - 2.5e-78 262.8 0.0 3.2e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME28605.1 - 9.3e-07 28.6 1.3 1.6e-06 27.9 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FTHFS PF01268.14 EME28606.1 - 1.5e-258 858.3 0.0 1.7e-258 858.1 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase NAD_binding_10 PF13460.1 EME28607.1 - 8.3e-17 61.7 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding EF-hand_1 PF00036.27 EME28608.1 - 1.7e-07 30.0 4.9 0.00015 20.8 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EME28608.1 - 3.8e-07 29.4 2.7 0.00016 21.2 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EME28608.1 - 7.4e-07 29.2 3.9 2.5e-06 27.5 2.6 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EME28608.1 - 4.5e-05 22.5 6.2 0.00015 20.9 0.5 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EME28608.1 - 0.00034 20.1 7.0 0.047 13.2 0.1 2.8 2 1 1 3 3 3 2 EF-hand domain pair DrsE_2 PF13686.1 EME28608.1 - 0.0049 16.6 0.6 0.0054 16.5 0.4 1.2 1 1 0 1 1 1 1 DsrE/DsrF/DrsH-like family TerB PF05099.8 EME28608.1 - 0.024 14.3 2.2 0.034 13.8 0.4 1.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB EF-hand_4 PF12763.2 EME28608.1 - 0.047 13.4 4.4 0.23 11.2 0.9 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand tify PF06200.9 EME28608.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 tify domain VCBS PF13517.1 EME28608.1 - 0.24 11.7 1.3 3.2 8.1 1.1 2.1 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MoaF PF10703.4 EME28609.1 - 0.056 12.5 0.1 0.1 11.6 0.0 1.4 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F Sugar_tr PF00083.19 EME28610.1 - 7.6e-14 51.1 19.7 2.6e-07 29.5 6.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME28610.1 - 9.9e-07 27.7 28.4 0.0021 16.8 2.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Isochorismatase PF00857.15 EME28611.1 - 0.00036 20.5 0.0 0.00045 20.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family RRM_1 PF00076.17 EME28612.1 - 6.1e-15 54.6 0.0 1.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28612.1 - 1.9e-12 46.9 0.0 3.8e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EME28612.1 - 1.4e-07 31.0 0.0 3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 EME28612.1 - 0.00039 20.2 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EME28612.1 - 0.0012 19.0 0.0 0.006 16.7 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TipAS PF07739.8 EME28612.1 - 0.52 10.6 4.4 2.1 8.6 1.1 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain RRM_1 PF00076.17 EME28613.1 - 6.1e-15 54.6 0.0 1.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28613.1 - 1.9e-12 46.9 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EME28613.1 - 1.4e-07 31.0 0.0 3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 EME28613.1 - 0.00039 20.2 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EME28613.1 - 0.0012 19.0 0.0 0.0059 16.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TipAS PF07739.8 EME28613.1 - 0.49 10.7 4.4 2.1 8.6 1.1 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain GTP_EFTU PF00009.22 EME28614.1 - 1.6e-37 128.7 3.1 1e-36 126.1 2.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EME28614.1 - 3.6e-29 100.8 0.6 1.1e-28 99.2 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EME28614.1 - 3.7e-08 33.3 1.0 9.5e-08 32.0 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EME28614.1 - 1.4e-07 30.9 0.0 2.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME28614.1 - 1.1e-06 29.1 0.5 2.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EME28614.1 - 4.5e-06 26.0 0.2 4.1e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.20 EME28614.1 - 1.5e-05 25.0 0.9 5.6e-05 23.1 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EME28614.1 - 3e-05 23.5 0.2 9.5e-05 21.9 0.1 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EME28614.1 - 0.00012 21.4 1.1 0.00043 19.6 0.8 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.10 EME28614.1 - 0.00026 20.5 0.0 0.0011 18.5 0.0 2.2 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.17 EME28614.1 - 0.00094 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.1 EME28614.1 - 0.018 14.5 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME28614.1 - 0.021 15.1 2.6 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EME28614.1 - 0.057 13.2 1.2 0.45 10.3 0.0 2.6 2 1 1 3 3 3 0 Dynamin family RelA_SpoT PF04607.12 EME28615.1 - 5.7e-26 90.7 0.1 1.1e-25 89.9 0.1 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.1 EME28615.1 - 5.5e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 HD domain SapB_1 PF05184.10 EME28615.1 - 0.0059 16.4 0.8 0.019 14.7 0.2 2.1 2 0 0 2 2 2 1 Saposin-like type B, region 1 Metallophos PF00149.23 EME28616.1 - 3.2e-45 153.9 0.1 4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1546 PF07571.8 EME28617.1 - 6.2e-27 93.5 0.0 7.3e-26 90.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EME28617.1 - 2.4e-17 62.6 0.3 5.4e-17 61.5 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EME28617.1 - 0.00069 19.6 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_U4 PF03419.8 EME28618.1 - 0.12 11.4 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Lzipper-MIP1 PF14389.1 EME28618.1 - 0.16 12.0 1.0 0.32 11.1 0.1 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1049 PF06305.6 EME28618.1 - 0.18 11.2 1.6 7.6 6.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) GAS PF13851.1 EME28619.1 - 0.0026 17.0 1.5 0.0032 16.6 1.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EME28619.1 - 0.025 14.3 3.3 0.041 13.6 2.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.1 EME28619.1 - 0.03 14.4 1.1 0.04 14.0 0.3 1.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DAO PF01266.19 EME28620.1 - 1.5e-50 172.1 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME28620.1 - 1.9e-05 24.5 0.1 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME28620.1 - 7e-05 22.9 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME28620.1 - 0.00011 21.3 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 EME28620.1 - 0.00027 20.9 0.5 0.0007 19.5 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.9 EME28620.1 - 0.00099 19.0 0.3 0.0026 17.6 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME28620.1 - 0.002 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME28620.1 - 0.0031 17.3 0.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.10 EME28620.1 - 0.0031 15.7 0.0 0.0048 15.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EME28620.1 - 0.0043 15.9 0.2 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME28620.1 - 0.0078 15.2 0.0 0.056 12.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Saccharop_dh PF03435.13 EME28620.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EME28620.1 - 0.063 13.1 0.0 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME28620.1 - 0.081 13.3 0.2 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EME28620.1 - 0.094 12.1 0.2 0.26 10.7 0.2 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EME28620.1 - 0.1 11.0 0.1 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EME28620.1 - 0.12 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EME28620.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EME28621.1 - 1.5e-50 172.1 0.0 1.8e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME28621.1 - 1.9e-05 24.5 0.1 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME28621.1 - 7e-05 22.9 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME28621.1 - 0.00011 21.3 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 EME28621.1 - 0.00027 20.9 0.5 0.0007 19.5 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.9 EME28621.1 - 0.00099 19.0 0.3 0.0026 17.6 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME28621.1 - 0.002 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME28621.1 - 0.0031 17.3 0.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.10 EME28621.1 - 0.0031 15.7 0.0 0.0048 15.1 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EME28621.1 - 0.0043 15.9 0.2 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME28621.1 - 0.0078 15.2 0.0 0.056 12.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Saccharop_dh PF03435.13 EME28621.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EME28621.1 - 0.063 13.1 0.0 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME28621.1 - 0.081 13.3 0.2 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EME28621.1 - 0.094 12.1 0.2 0.26 10.7 0.2 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EME28621.1 - 0.1 11.0 0.1 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EME28621.1 - 0.12 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EME28621.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2391 PF09622.5 EME28625.1 - 0.15 11.1 0.3 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Arch_ATPase PF01637.13 EME28627.1 - 6.3e-10 39.1 0.0 0.0008 19.1 0.0 2.9 2 0 0 2 2 2 2 Archaeal ATPase AAA_22 PF13401.1 EME28627.1 - 0.018 15.2 0.7 6.4 6.9 0.0 4.1 5 2 0 5 5 5 0 AAA domain ATP_bind_1 PF03029.12 EME28627.1 - 0.16 11.4 0.2 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aa_trans PF01490.13 EME28629.1 - 4.5e-48 163.7 35.1 5.7e-48 163.3 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME28629.1 - 8.8e-07 28.0 17.1 8.8e-07 28.0 11.9 2.3 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EME28629.1 - 0.00011 20.9 24.8 0.00022 19.9 17.2 1.4 1 0 0 1 1 1 1 Spore germination protein Ribosomal_S8 PF00410.14 EME28629.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S8 NnrU PF07298.6 EME28630.1 - 1.8e-43 148.1 8.7 2.9e-43 147.4 6.0 1.3 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.8 EME28630.1 - 2.1e-05 24.5 2.3 2.1e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EME28630.1 - 0.0077 16.4 0.9 0.059 13.5 0.0 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Kinesin PF00225.18 EME28631.1 - 2.5e-06 26.4 0.2 3.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain RNA_pol_Rpb1_R PF05001.8 EME28631.1 - 0.46 10.7 5.7 1.4 9.2 4.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Kinesin PF00225.18 EME28632.1 - 2.6e-06 26.3 0.2 4e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain RNA_pol_Rpb1_R PF05001.8 EME28632.1 - 0.44 10.7 5.7 1.5 9.1 4.0 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat ATP-grasp_4 PF13535.1 EME28633.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain V-SNARE_C PF12352.3 EME28634.1 - 2e-12 46.9 1.5 2e-12 46.9 1.0 1.7 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EME28634.1 - 7.4e-06 25.5 1.6 6.3e-05 22.6 0.0 2.7 1 1 2 3 3 3 1 Sec20 Snapin_Pallidin PF14712.1 EME28634.1 - 0.013 15.7 1.0 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin YihI PF04220.7 EME28634.1 - 0.027 13.7 0.2 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) TarH PF02203.10 EME28634.1 - 0.063 13.1 2.8 0.16 11.8 1.9 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue Syntaxin_2 PF14523.1 EME28634.1 - 0.13 12.3 3.0 0.099 12.6 0.8 1.7 1 1 1 2 2 2 0 Syntaxin-like protein Med10 PF09748.4 EME28634.1 - 0.14 11.9 0.7 0.2 11.4 0.5 1.6 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex SNF2_N PF00176.18 EME28635.1 - 4.7e-77 258.7 0.0 7.8e-77 258.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EME28635.1 - 7.9e-39 132.0 2.6 1.7e-38 130.9 0.7 2.5 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.26 EME28635.1 - 4.4e-16 58.5 0.0 1.8e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME28635.1 - 2.8e-07 30.5 0.0 2.8e-07 30.5 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EME28635.1 - 1.1e-06 27.7 0.1 1.1e-05 24.4 0.1 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.26 EME28635.1 - 9.2e-06 25.6 8.5 0.00064 19.7 0.0 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain DEAD PF00270.24 EME28635.1 - 5.4e-05 22.7 0.0 0.00045 19.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PMI_typeI PF01238.16 EME28636.1 - 6.6e-89 298.4 0.0 7.8e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EME28636.1 - 0.0027 17.3 0.0 1.8 8.2 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_2 PF07883.6 EME28636.1 - 0.13 11.7 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 Cupin domain FAD-oxidase_C PF02913.14 EME28637.1 - 5.5e-63 212.5 0.0 1.3e-62 211.4 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EME28637.1 - 3.2e-40 136.8 0.0 5e-40 136.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2389 PF09493.5 EME28638.1 - 6.5e-07 29.5 0.0 9.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) DnaJ_CXXCXGXG PF00684.14 EME28638.1 - 4.2 7.4 6.6 10 6.2 0.1 2.9 2 1 1 3 3 3 0 DnaJ central domain DUF2389 PF09493.5 EME28639.1 - 3.2e-13 49.7 0.2 4.8e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) Transp_Tc5_C PF04236.10 EME28639.1 - 0.81 9.9 11.0 0.5 10.6 2.1 2.6 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain DnaJ_CXXCXGXG PF00684.14 EME28639.1 - 3.1 7.9 19.0 4 7.5 3.1 4.0 3 2 1 4 4 4 0 DnaJ central domain Mito_carr PF00153.22 EME28640.1 - 9.4e-28 95.7 6.2 3.6e-12 45.8 0.1 4.1 3 1 1 4 4 4 3 Mitochondrial carrier protein Glyco_hydro_100 PF12899.2 EME28640.1 - 0.082 11.2 0.0 0.18 10.1 0.0 1.5 2 0 0 2 2 2 0 Alkaline and neutral invertase Hemagglutinin PF00509.13 EME28640.1 - 0.22 9.5 0.4 0.38 8.8 0.3 1.3 1 0 0 1 1 1 0 Haemagglutinin OTU PF02338.14 EME28641.1 - 3.8e-18 66.2 0.5 7.4e-18 65.2 0.4 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME28641.1 - 0.00045 19.6 0.1 0.51 9.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain GCIP PF13324.1 EME28641.1 - 0.085 12.0 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Chorismate_bind PF00425.13 EME28642.1 - 6.6e-87 291.0 0.0 9.3e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EME28642.1 - 2.5e-42 144.5 0.0 3.9e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EME28642.1 - 7.6e-18 64.8 0.0 2.6e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EME28642.1 - 1.4e-08 34.4 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 TRAPPC10 PF12584.3 EME28644.1 - 5.1e-05 22.8 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.12 EME28644.1 - 0.013 15.3 0.1 0.4 10.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME28644.1 - 0.28 11.1 1.4 20 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec1 PF00995.18 EME28645.1 - 2.1e-138 462.4 1.4 2.5e-138 462.2 0.9 1.1 1 0 0 1 1 1 1 Sec1 family Furin-like PF00757.15 EME28646.1 - 2.8e-06 27.0 17.3 4.1e-05 23.2 4.6 2.3 1 1 1 2 2 2 2 Furin-like cysteine rich region Vanabin-2 PF11437.3 EME28646.1 - 0.47 10.4 7.7 3.3 7.7 5.0 2.1 1 1 1 2 2 2 0 Vanadium-binding protein 2 DUF4215 PF13948.1 EME28646.1 - 1 9.6 15.2 0.19 11.9 1.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4215) Fer4_3 PF12798.2 EME28646.1 - 3.8 8.3 24.7 27 5.6 0.3 6.2 6 0 0 6 6 6 0 4Fe-4S binding domain GF_recep_IV PF14843.1 EME28646.1 - 5.2 6.6 15.1 13 5.3 4.3 2.8 1 1 1 2 2 2 0 Growth factor receptor domain IV ERCC4 PF02732.10 EME28647.1 - 9.9e-20 70.7 0.1 4.1e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 EME28647.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain PI3_PI4_kinase PF00454.22 EME28648.1 - 6.1e-60 202.6 0.7 2e-59 200.9 0.5 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EME28648.1 - 2.7e-47 161.4 9.5 2.7e-47 161.4 6.6 2.7 2 1 0 2 2 2 1 FAT domain Rapamycin_bind PF08771.6 EME28648.1 - 1.3e-38 131.1 0.2 8.7e-38 128.4 0.2 2.7 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 EME28648.1 - 2.6e-17 63.2 3.6 2.9e-12 46.8 0.1 4.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FATC PF02260.15 EME28648.1 - 3.7e-15 55.0 2.6 4.9e-15 54.6 0.3 2.4 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.1 EME28648.1 - 5.6e-10 39.3 7.5 4.6e-05 23.6 0.0 6.7 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.17 EME28648.1 - 0.00013 21.7 4.0 10 6.4 0.0 7.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EME28648.1 - 0.056 13.9 14.2 7.7 7.1 0.1 7.4 6 2 2 8 8 8 0 HEAT-like repeat AAA_17 PF13207.1 EME28649.1 - 0.00036 21.3 0.0 0.00066 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EME28649.1 - 0.0034 17.2 0.0 0.57 10.0 0.0 2.7 2 1 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 EME28649.1 - 0.007 16.2 0.0 0.021 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME28650.1 - 1.1e-98 326.4 0.0 6.5e-23 81.0 0.0 9.4 8 1 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME28650.1 - 7.4e-30 103.2 0.0 1e-11 44.5 0.0 6.0 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EME28650.1 - 7.4e-20 71.4 0.0 7.6e-05 22.9 0.0 6.2 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME28650.1 - 2.9e-18 66.2 0.0 0.012 15.7 0.0 8.9 9 1 0 9 9 7 3 AAA domain AAA_14 PF13173.1 EME28650.1 - 1.5e-17 63.7 0.0 0.0056 16.5 0.0 7.6 7 0 0 7 7 7 3 AAA domain AAA_16 PF13191.1 EME28650.1 - 5.4e-17 62.3 0.1 0.055 13.4 0.0 6.9 6 0 0 6 6 6 4 AAA ATPase domain AAA_18 PF13238.1 EME28650.1 - 3.8e-16 59.5 0.3 0.028 14.7 0.0 7.6 7 0 0 7 7 5 4 AAA domain AAA_17 PF13207.1 EME28650.1 - 1.9e-15 57.7 0.0 0.87 10.4 0.0 8.0 7 0 0 7 7 6 3 AAA domain AAA_33 PF13671.1 EME28650.1 - 3.5e-12 46.3 0.0 0.016 15.0 0.0 5.7 5 0 0 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.1 EME28650.1 - 2.2e-11 43.9 0.0 0.36 10.8 0.0 7.0 7 0 0 7 7 5 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EME28650.1 - 5.6e-11 42.2 0.1 0.14 11.6 0.0 6.1 6 0 0 6 6 5 2 Sigma-54 interaction domain Miro PF08477.8 EME28650.1 - 9.3e-11 42.2 0.2 2.6 8.5 0.0 6.9 7 0 0 7 7 5 1 Miro-like protein AAA_19 PF13245.1 EME28650.1 - 2.8e-10 39.7 0.1 0.082 12.6 0.0 5.5 5 0 0 5 5 5 1 Part of AAA domain NACHT PF05729.7 EME28650.1 - 4.4e-10 39.4 0.6 0.49 10.0 0.0 6.3 5 0 0 5 5 5 2 NACHT domain T2SE PF00437.15 EME28650.1 - 8e-10 38.0 0.0 1.1 8.1 0.0 5.7 5 0 0 5 5 5 2 Type II/IV secretion system protein UPF0079 PF02367.12 EME28650.1 - 1.7e-09 37.3 0.1 0.057 13.0 0.0 5.8 5 0 0 5 5 5 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EME28650.1 - 3e-09 36.2 0.1 0.49 9.5 0.0 6.0 6 0 0 6 6 6 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EME28650.1 - 5.8e-09 36.0 0.0 5.3 7.2 0.0 6.1 5 0 0 5 5 5 0 RNA helicase AAA_29 PF13555.1 EME28650.1 - 8.6e-09 34.8 0.2 4.8 6.7 0.0 5.8 6 0 0 6 6 5 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EME28650.1 - 1.3e-08 34.1 0.0 0.27 10.3 0.0 5.4 5 0 0 5 5 5 2 Zeta toxin IstB_IS21 PF01695.12 EME28650.1 - 7.1e-08 32.0 0.0 1.3 8.3 0.0 4.9 5 0 0 5 5 5 2 IstB-like ATP binding protein MobB PF03205.9 EME28650.1 - 4.3e-07 29.7 0.4 3.3 7.4 0.0 5.8 6 0 0 6 6 5 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EME28650.1 - 1.2e-06 27.7 0.3 0.92 8.4 0.0 5.4 6 0 0 6 6 5 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EME28650.1 - 1.7e-06 28.0 0.2 3.9 7.4 0.0 6.0 6 0 0 6 6 5 0 AAA domain AAA_30 PF13604.1 EME28650.1 - 1.9e-06 27.6 0.0 3.3 7.2 0.0 5.3 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EME28650.1 - 4.6e-06 26.1 0.0 6.9 6.0 0.0 5.2 5 0 0 5 5 5 0 AAA domain PduV-EutP PF10662.4 EME28650.1 - 7.5e-06 25.4 3.3 0.88 9.0 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EME28650.1 - 1.3e-05 24.8 0.0 3.7 7.0 0.0 5.3 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 EME28650.1 - 1.7e-05 24.4 0.0 3.5 7.1 0.0 5.1 5 0 0 5 5 5 1 DEAD/DEAH box helicase VWA PF00092.23 EME28650.1 - 0.00021 21.0 0.5 0.00042 20.0 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.16 EME28650.1 - 0.00024 20.3 10.9 0.64 9.1 0.1 8.1 7 3 0 8 8 8 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EME28650.1 - 0.0018 18.0 0.0 3.8 7.1 0.0 4.2 4 0 0 4 4 4 0 NTPase CPT PF07931.7 EME28650.1 - 0.0033 17.0 0.0 9 5.8 0.0 4.9 4 1 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 EME28650.1 - 0.0064 15.9 0.3 5.8 6.3 0.0 3.7 4 0 0 4 4 3 0 FtsK/SpoIIIE family SRP54 PF00448.17 EME28650.1 - 0.0089 15.4 4.4 4 6.8 0.0 4.1 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EME28650.1 - 0.015 15.6 28.2 0.26 11.5 0.0 8.1 10 0 0 10 10 6 0 ABC transporter ATP-synt_ab PF00006.20 EME28650.1 - 0.021 14.3 0.0 2.2 7.7 0.0 3.3 4 1 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.2 EME28650.1 - 0.056 12.9 0.0 3.9 6.9 0.0 3.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 MMR_HSR1 PF01926.18 EME28650.1 - 0.18 11.7 0.0 2.4e+02 1.6 0.0 4.9 6 0 0 6 6 5 0 50S ribosome-binding GTPase TIP49 PF06068.8 EME28650.1 - 0.59 8.7 0.8 70 1.9 0.0 3.7 4 0 0 4 4 4 0 TIP49 C-terminus DUF853 PF05872.7 EME28650.1 - 4.3 5.5 5.4 9.6 4.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) EF-hand_7 PF13499.1 EME28651.1 - 1.3e-19 70.0 5.6 5.1e-10 39.3 1.8 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME28651.1 - 5.7e-19 65.9 6.0 6.2e-06 25.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EME28651.1 - 1e-14 53.0 8.9 4.6e-06 26.0 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EME28651.1 - 1e-14 53.8 6.5 0.012 15.2 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EME28651.1 - 4.5e-10 38.4 3.6 3.7e-05 22.8 0.2 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EME28651.1 - 2.5e-05 24.1 0.1 0.00029 20.6 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain Dockerin_1 PF00404.13 EME28651.1 - 0.076 12.7 2.2 2.9 7.7 0.1 3.1 3 0 0 3 3 3 0 Dockerin type I repeat Voldacs PF03517.8 EME28652.1 - 1.3e-09 38.0 0.9 2.5e-09 37.1 0.6 1.6 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling PAP2 PF01569.16 EME28653.1 - 1.6e-23 82.7 2.6 1.6e-23 82.7 1.8 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EME28653.1 - 0.044 14.0 1.7 0.21 11.9 1.2 2.1 1 1 0 1 1 1 0 PAP2 superfamily C-terminal TctB PF07331.6 EME28653.1 - 2 8.0 7.3 0.32 10.6 0.3 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Polysacc_synt_C PF14667.1 EME28653.1 - 2 8.1 6.4 0.2 11.4 0.8 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Pho88 PF10032.4 EME28654.1 - 1.2e-39 135.4 0.0 1.5e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) TerC PF03741.11 EME28655.1 - 3e-50 170.2 3.4 4.9e-50 169.5 2.4 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family NnrU PF07298.6 EME28655.1 - 0.0009 18.6 1.0 0.0014 18.0 0.7 1.3 1 0 0 1 1 1 1 NnrU protein TauE PF01925.14 EME28655.1 - 0.69 9.3 8.8 0.27 10.6 2.4 2.5 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Phage_T4_Ndd PF06591.6 EME28656.1 - 0.049 13.2 0.1 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) E1-E2_ATPase PF00122.15 EME28657.1 - 1.1e-18 67.0 0.0 1.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EME28657.1 - 5.9e-06 25.6 0.0 5.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus TMEM223 PF14640.1 EME28658.1 - 9e-09 35.4 3.5 1.2e-07 31.7 2.5 2.3 1 1 0 1 1 1 1 Transmembrane protein 223 WRKY PF03106.10 EME28658.1 - 0.18 11.6 3.6 0.32 10.8 1.0 2.2 2 0 0 2 2 2 0 WRKY DNA -binding domain Cys_Met_Meta_PP PF01053.15 EME28659.1 - 2.5e-154 513.2 0.0 2.8e-154 513.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EME28659.1 - 1e-09 37.8 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EME28659.1 - 5.2e-07 29.0 0.0 9.1e-07 28.2 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EME28659.1 - 0.0028 16.4 0.0 0.0092 14.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EME28659.1 - 0.0073 14.6 0.0 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase LT-IIB PF06453.6 EME28659.1 - 0.084 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Beta_elim_lyase PF01212.16 EME28659.1 - 0.15 11.1 0.1 0.29 10.2 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase bZIP_1 PF00170.16 EME28660.1 - 2.1e-10 40.3 17.8 3.4e-10 39.7 8.2 2.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME28660.1 - 2.2e-07 30.5 11.4 2.2e-07 30.5 7.9 2.4 1 1 1 2 2 2 1 Basic region leucine zipper TSC22 PF01166.13 EME28660.1 - 1.1 9.3 6.3 0.71 9.8 0.4 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Med27 PF11571.3 EME28663.1 - 0.013 15.6 4.3 0.02 15.0 1.0 2.6 2 1 0 2 2 2 0 Mediator complex subunit 27 LTV PF04180.9 EME28663.1 - 0.035 13.6 0.3 0.041 13.3 0.2 1.1 1 0 0 1 1 1 0 Low temperature viability protein DUF1510 PF07423.6 EME28665.1 - 0.049 12.9 0.4 0.079 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ELMO_CED12 PF04727.8 EME28667.1 - 1.9e-36 125.1 1.9 2.7e-36 124.6 1.3 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Ins_P5_2-kin PF06090.7 EME28667.1 - 0.023 13.7 0.3 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Ras PF00071.17 EME28668.1 - 7e-63 210.8 0.0 9.8e-63 210.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME28668.1 - 4.4e-18 65.8 0.1 9.8e-18 64.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME28668.1 - 1.7e-12 46.8 0.4 2.3e-12 46.5 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME28668.1 - 4.4e-06 26.6 0.0 6.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EME28668.1 - 0.00025 20.2 0.0 0.00043 19.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME28668.1 - 0.00094 18.6 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME28668.1 - 0.0011 18.2 0.3 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EME28668.1 - 0.002 17.3 0.1 0.0087 15.2 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME28668.1 - 0.007 16.5 0.1 0.035 14.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28668.1 - 0.029 14.3 0.4 0.12 12.3 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EME28668.1 - 0.034 13.7 0.0 0.082 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EME28668.1 - 0.043 13.0 0.2 0.96 8.6 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EME28668.1 - 0.048 13.5 0.0 0.21 11.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain CPT PF07931.7 EME28668.1 - 0.068 12.7 0.2 0.12 11.9 0.2 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 EME28668.1 - 0.091 13.0 0.3 0.2 11.9 0.2 1.9 1 1 0 1 1 1 0 ABC transporter GTP1_OBG PF01018.17 EME28669.1 - 1.1e-33 116.0 6.0 2.7e-22 79.0 1.8 2.1 1 1 1 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EME28669.1 - 1.2e-22 79.9 0.0 1.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME28669.1 - 3.3e-11 42.7 0.0 1.3e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EME28669.1 - 1.2e-05 24.5 0.0 0.00011 21.4 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME28669.1 - 6e-05 22.5 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME28669.1 - 0.00041 19.5 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EME28669.1 - 0.00056 19.5 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NOG1 PF06858.9 EME28669.1 - 0.0023 17.7 0.1 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) cobW PF02492.14 EME28669.1 - 0.003 17.0 0.0 0.76 9.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EME28669.1 - 0.0044 17.4 0.0 0.0084 16.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EME28669.1 - 0.012 15.4 0.0 2.3 7.9 0.0 2.2 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EME28669.1 - 0.025 14.0 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EME28669.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter UPF0081 PF03652.10 EME28670.1 - 6.9e-26 90.9 0.0 8.5e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) Pam16 PF03656.8 EME28671.1 - 1.3e-22 79.9 0.0 1.4e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Pam16 HTH_17 PF12728.2 EME28671.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain RPT PF13446.1 EME28671.1 - 0.0074 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 A repeated domain in UCH-protein DnaJ PF00226.26 EME28671.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain HTH_28 PF13518.1 EME28671.1 - 0.045 13.7 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TylF PF05711.6 EME28671.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) NESP55 PF06390.7 EME28671.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) HTH_DeoR PF08220.7 EME28671.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Mt_ATP-synt_D PF05873.7 EME28672.1 - 0.005 16.4 0.1 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) zf-BED PF02892.10 EME28672.1 - 0.32 10.7 8.1 3.8 7.3 0.1 3.7 3 0 0 3 3 3 0 BED zinc finger CEP44 PF15007.1 EME28673.1 - 3.3e-05 23.5 0.4 7.5e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 SlyX PF04102.7 EME28673.1 - 0.0011 19.3 1.6 0.0011 19.3 1.1 2.4 3 0 0 3 3 3 1 SlyX DUF3505 PF12013.3 EME28674.1 - 0.028 14.6 4.2 1.6 9.0 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) Gly-zipper_Omp PF13488.1 EME28675.1 - 0.009 15.6 4.4 0.047 13.3 3.1 1.9 1 1 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.1 EME28675.1 - 0.87 9.1 4.5 7.1 6.2 3.4 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper ATP-synt_ab_C PF00306.22 EME28676.1 - 3.9e-14 53.0 0.0 5.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.20 EME28676.1 - 7.1e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab PF00006.20 EME28677.1 - 4.6e-39 134.1 0.0 6.6e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EME28677.1 - 7.2e-13 48.5 0.5 1.2e-12 47.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EME28677.1 - 0.00045 20.0 0.3 0.001 18.9 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Rtf2 PF04641.7 EME28677.1 - 0.11 11.7 0.3 0.18 10.9 0.0 1.4 2 0 0 2 2 2 0 Rtf2 RING-finger DnaJ PF00226.26 EME28678.1 - 5.5e-12 45.2 0.2 8.4e-12 44.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DUF682 PF05081.7 EME28678.1 - 0.0036 16.8 0.3 0.0052 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF682) Chorein_N PF12624.2 EME28679.1 - 2e-12 46.6 0.2 4.6e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Tyr-DNA_phospho PF06087.7 EME28681.1 - 9.2e-82 275.0 2.1 1.1e-81 274.7 1.4 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-met PF12874.2 EME28682.1 - 9.2e-06 25.6 0.7 9.2e-06 25.6 0.5 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EME28682.1 - 0.002 17.7 3.9 0.0055 16.3 2.7 1.8 1 1 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fibrillarin PF01269.12 EME28683.1 - 7.6e-111 368.5 0.0 9.4e-111 368.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EME28683.1 - 0.00024 20.7 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EME28683.1 - 0.029 13.8 0.1 0.053 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EME28683.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Apolipoprotein PF01442.13 EME28684.1 - 3.7e-17 62.5 0.0 8.7e-05 22.1 0.0 3.7 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EME28684.1 - 2.5e-16 59.7 6.9 0.012 15.4 0.1 6.7 1 1 5 6 6 6 5 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.6 EME28684.1 - 2.9e-09 37.1 4.9 0.052 13.5 0.0 5.3 2 2 3 5 5 5 3 Apolipophorin-III precursor (apoLp-III) GvpL_GvpF PF06386.6 EME28684.1 - 2.7e-08 33.6 1.0 0.59 9.6 0.0 4.0 3 2 0 5 5 4 3 Gas vesicle synthesis protein GvpL/GvpF Phage_GPO PF05929.6 EME28684.1 - 2.6e-06 26.8 2.4 0.87 8.7 0.0 4.3 1 1 3 4 4 4 2 Phage capsid scaffolding protein (GPO) serine peptidase WXG100 PF06013.7 EME28684.1 - 1e-05 25.4 0.0 31 4.6 0.0 6.6 2 2 3 6 6 6 0 Proteins of 100 residues with WXG DUF2397 PF09660.5 EME28684.1 - 3.9e-05 22.4 1.7 2.3 6.6 0.0 3.7 2 2 0 3 3 3 3 Protein of unknown function (DUF2397) Bacillus_HBL PF05791.6 EME28684.1 - 5.2e-05 22.6 33.9 0.00056 19.3 4.3 4.5 1 1 3 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) PB1 PF00564.19 EME28684.1 - 5.8e-05 22.6 6.0 4.1 7.1 0.0 5.1 5 0 0 5 5 5 0 PB1 domain SF-assemblin PF06705.6 EME28684.1 - 0.00011 21.4 7.1 0.89 8.6 0.1 3.9 1 1 3 4 4 4 3 SF-assemblin/beta giardin YlqD PF11068.3 EME28684.1 - 0.00015 21.7 0.0 3.8 7.5 0.0 5.1 3 2 3 6 6 6 1 YlqD protein DUF883 PF05957.8 EME28684.1 - 0.00039 20.7 0.0 35 4.8 0.0 4.5 5 1 1 6 6 4 0 Bacterial protein of unknown function (DUF883) Med4 PF10018.4 EME28684.1 - 0.0013 18.1 4.4 6.9 6.0 0.1 4.1 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Dict-STAT-coil PF09267.5 EME28684.1 - 0.0016 18.6 8.0 5.6 7.2 0.2 4.7 4 0 0 4 4 4 0 Dictyostelium STAT, coiled coil DUF489 PF04356.7 EME28684.1 - 0.0018 17.9 12.9 0.33 10.5 1.3 4.0 1 1 3 4 4 4 1 Protein of unknown function (DUF489) DUF4417 PF14386.1 EME28684.1 - 0.003 16.8 6.0 5.7 6.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4417) SMP_2 PF10144.4 EME28684.1 - 0.0031 16.6 4.1 7.6 5.5 0.1 3.2 3 0 0 3 3 3 0 Bacterial virulence factor haemolysin Utp12 PF04003.7 EME28684.1 - 0.0032 17.3 0.0 41 4.1 0.0 5.3 4 2 0 4 4 4 0 Dip2/Utp12 Family Mad3_BUB1_I PF08311.7 EME28684.1 - 0.0032 17.2 3.4 21 4.9 0.0 4.5 3 2 0 4 4 4 0 Mad3/BUB1 homology region 1 Carbpep_Y_N PF05388.6 EME28684.1 - 0.012 15.7 5.7 56 3.9 0.1 5.7 1 1 1 4 4 4 0 Carboxypeptidase Y pro-peptide DUF3113 PF11310.3 EME28684.1 - 0.015 14.9 21.0 28 4.4 0.1 7.9 6 2 2 8 8 8 0 Protein of unknown function (DUF3113) DUF2884 PF11101.3 EME28684.1 - 0.02 14.2 20.0 0.022 14.1 0.3 4.8 1 1 4 5 5 5 0 Protein of unknown function (DUF2884) Dynamin_M PF01031.15 EME28684.1 - 0.022 13.5 12.8 0.91 8.2 0.3 4.2 1 1 0 4 4 4 0 Dynamin central region DUF4618 PF15397.1 EME28684.1 - 0.039 13.2 23.6 2.3 7.4 0.0 5.5 1 1 2 5 5 5 0 Domain of unknown function (DUF4618) Flt3_lig PF02947.9 EME28684.1 - 0.051 13.4 0.0 1e+02 2.7 0.0 3.9 3 1 0 4 4 3 0 flt3 ligand DUF826 PF05696.6 EME28684.1 - 0.09 12.9 3.0 1.2e+02 2.9 0.0 4.6 5 0 0 5 5 4 0 Protein of unknown function (DUF826) Proho_convert PF12177.3 EME28684.1 - 0.092 12.3 6.4 27 4.4 0.1 3.8 3 0 0 3 3 3 0 Prohormone convertase enzyme MA3 PF02847.12 EME28684.1 - 0.15 11.7 6.5 6.6 6.4 0.2 4.2 3 2 0 3 3 3 0 MA3 domain DUF4631 PF15450.1 EME28684.1 - 0.17 10.1 4.6 25 2.9 1.5 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4631) MazG-like PF12643.2 EME28684.1 - 0.23 11.4 10.1 1.1 9.2 0.2 5.5 3 3 1 7 7 5 0 MazG-like family IF2_N PF04760.10 EME28684.1 - 0.24 11.1 7.4 47 3.7 0.0 4.9 5 0 0 5 5 4 0 Translation initiation factor IF-2, N-terminal region YtxH PF12732.2 EME28684.1 - 0.29 11.5 15.9 1.5e+04 -8.3 10.9 6.8 1 1 0 1 1 0 0 YtxH-like protein DUF2746 PF10874.3 EME28684.1 - 0.58 10.3 2.8 16 5.7 0.0 4.8 5 1 1 6 6 3 0 Protein of unknown function (DUF2746) CAT PF00302.13 EME28684.1 - 0.77 9.3 17.8 11 5.6 0.2 4.8 1 1 2 4 4 4 0 Chloramphenicol acetyltransferase Mer2 PF09074.5 EME28684.1 - 1.9 8.3 20.1 28 4.5 3.2 4.7 1 1 3 4 4 4 0 Mer2 Mt_ATP-synt_D PF05873.7 EME28684.1 - 8.1 6.0 12.9 2.9 7.5 0.4 4.2 2 2 2 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) DNA_ligase_A_M PF01068.16 EME28685.1 - 1.1e-35 122.9 0.2 2e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME28685.1 - 4.8e-27 94.8 0.0 9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME28685.1 - 1.5e-12 47.7 0.0 4.6e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EME28685.1 - 1.1e-05 25.5 0.5 7.1e-05 22.8 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Acyl-CoA_dh_1 PF00441.19 EME28686.1 - 3.5e-40 137.5 0.2 6.9e-40 136.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME28686.1 - 2.2e-38 131.2 0.0 4.3e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME28686.1 - 9e-20 69.9 0.0 1.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME28686.1 - 2.5e-16 60.1 0.0 4.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EME28686.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal PI-PLC-X PF00388.14 EME28687.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain SVM_signal PF12113.3 EME28687.1 - 0.046 13.5 3.3 0.086 12.6 2.3 1.4 1 0 0 1 1 1 0 SVM protein signal sequence Ribosomal_L50 PF10501.4 EME28688.1 - 0.016 15.1 0.2 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Ribosomal subunit 39S SPA PF08616.5 EME28689.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Stabilization of polarity axis GATase PF00117.23 EME28690.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase PF00117.23 EME28691.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I p25-alpha PF05517.7 EME28692.1 - 0.014 15.6 0.1 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 p25-alpha Cys_Met_Meta_PP PF01053.15 EME28693.1 - 1.2e-134 448.4 0.2 2e-134 447.7 0.1 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EME28693.1 - 2.6e-08 33.2 0.0 3.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME28693.1 - 6.4e-07 28.4 0.2 1.3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME28693.1 - 2.2e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Ribonuc_L-PSP PF01042.16 EME28694.1 - 1.2e-55 186.4 0.4 1.3e-31 108.8 0.0 2.2 2 0 0 2 2 2 2 Endoribonuclease L-PSP bZIP_1 PF00170.16 EME28695.1 - 3.3e-09 36.5 8.9 3.3e-09 36.5 6.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME28695.1 - 2.7e-05 23.9 12.1 7.1e-05 22.5 8.4 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF4618 PF15397.1 EME28695.1 - 0.0033 16.7 2.0 0.0039 16.5 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) DUF4200 PF13863.1 EME28695.1 - 0.026 14.4 1.7 0.026 14.4 1.2 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) YARHG PF13308.1 EME28695.1 - 0.054 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 YARHG domain Ribosomal_L36e PF01158.13 EME28695.1 - 0.056 13.3 2.3 0.15 12.0 1.6 1.7 1 0 0 1 1 1 0 Ribosomal protein L36e bZIP_Maf PF03131.12 EME28695.1 - 0.4 10.9 10.0 0.075 13.3 3.6 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor CaM_binding PF07839.6 EME28695.1 - 6 7.1 10.0 0.52 10.5 1.3 2.5 2 0 0 2 2 2 0 Plant calmodulin-binding domain WD40 PF00400.27 EME28696.1 - 7.5e-34 114.3 11.1 3.8e-09 36.0 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME28696.1 - 8.7e-06 25.5 0.1 0.0013 18.4 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EME28696.1 - 0.014 14.1 0.7 0.3 9.7 0.5 2.8 1 1 0 1 1 1 0 Nup133 N terminal like AIG2_2 PF13772.1 EME28697.1 - 1.7e-07 31.2 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EME28697.1 - 0.081 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family Peptidase_M17 PF00883.16 EME28698.1 - 3.8e-88 295.3 0.0 5.1e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain TMF_TATA_bd PF12325.3 EME28699.1 - 0.0068 16.1 2.3 0.0094 15.6 1.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF641 PF04859.7 EME28699.1 - 0.031 14.0 0.9 0.039 13.7 0.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EME28699.1 - 0.033 14.0 2.6 0.092 12.5 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EME28699.1 - 0.05 13.1 1.8 0.063 12.8 1.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 EME28699.1 - 0.071 12.8 1.2 0.078 12.7 0.2 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper GreA_GreB_N PF03449.10 EME28699.1 - 0.14 12.1 6.3 0.27 11.3 1.0 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Spc42p PF11544.3 EME28699.1 - 0.2 11.6 0.3 0.2 11.6 0.2 1.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF4201 PF13870.1 EME28699.1 - 0.27 10.6 6.4 0.69 9.3 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1843 PF08898.5 EME28699.1 - 0.33 11.0 1.6 0.46 10.5 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) ADIP PF11559.3 EME28699.1 - 0.39 10.6 5.8 5.7 6.8 0.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 EME28699.1 - 0.54 10.7 4.9 0.38 11.2 0.8 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EME28699.1 - 1.1 8.8 4.9 1.7 8.2 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EME28699.1 - 8 6.3 7.6 1.4 8.7 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SAM_1 PF00536.25 EME28702.1 - 0.00067 19.7 0.0 0.0032 17.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Arch_ATPase PF01637.13 EME28702.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF1654 PF07867.6 EME28707.1 - 0.084 12.2 0.0 0.25 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Put_Phosphatase PF06888.7 EME28707.1 - 0.1 11.7 0.4 0.32 10.1 0.1 1.9 2 0 0 2 2 2 0 Putative Phosphatase Post_transc_reg PF13797.1 EME28708.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Post-transcriptional regulator FA_hydroxylase PF04116.8 EME28710.1 - 1.3e-11 44.8 9.0 1.3e-11 44.8 6.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sugar_tr PF00083.19 EME28711.1 - 1.1e-90 304.3 29.9 1.3e-90 304.1 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28711.1 - 1.3e-25 89.9 26.2 1.3e-25 89.9 18.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Rib_5-P_isom_A PF06026.9 EME28712.1 - 7.8e-59 197.8 0.1 9.7e-59 197.5 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EME28712.1 - 0.0028 17.3 0.0 0.43 10.1 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 EME28712.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Hemerythrin PF01814.18 EME28713.1 - 4.7e-09 36.5 1.8 1.1e-08 35.2 1.2 1.7 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2956 PF11169.3 EME28713.1 - 0.12 12.2 0.6 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TAFII28 PF04719.9 EME28714.1 - 3e-23 81.3 0.1 5.5e-23 80.5 0.0 1.4 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Exonuc_X-T_C PF08411.5 EME28714.1 - 0.014 14.4 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal DUF2849 PF11011.3 EME28714.1 - 0.24 11.6 1.2 0.46 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) TAFII28 PF04719.9 EME28715.1 - 3e-23 81.4 0.1 6.1e-23 80.4 0.0 1.5 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Exonuc_X-T_C PF08411.5 EME28715.1 - 0.017 14.1 0.2 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal AAA_23 PF13476.1 EME28715.1 - 0.028 14.7 0.3 0.028 14.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF2849 PF11011.3 EME28715.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2849) Ctr PF04145.10 EME28716.1 - 3.9e-09 36.6 5.5 3.9e-09 36.6 3.8 4.3 4 1 1 5 5 5 2 Ctr copper transporter family DUF4079 PF13301.1 EME28716.1 - 0.16 11.9 10.7 0.042 13.8 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4231 PF14015.1 EME28716.1 - 2 8.4 13.8 3.8 7.5 0.3 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) Ninjurin PF04923.7 EME28716.1 - 2.2 8.0 7.0 15 5.4 0.1 3.7 3 1 1 4 4 4 0 Ninjurin Porin_3 PF01459.17 EME28717.1 - 2.9e-20 72.7 0.2 5.6e-20 71.7 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic porin DUF4033 PF13225.1 EME28718.1 - 2.5e-33 113.5 2.9 6.3e-33 112.2 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4033) DUF1664 PF07889.7 EME28719.1 - 9e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EME28719.1 - 0.0042 16.9 1.7 0.015 15.1 0.5 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF648 PF04890.8 EME28719.1 - 0.037 13.2 0.7 0.064 12.4 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF648) TctB PF07331.6 EME28719.1 - 0.055 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family V-ATPase_C PF03223.10 EME28719.1 - 0.063 12.1 1.1 0.09 11.6 0.8 1.2 1 0 0 1 1 1 0 V-ATPase subunit C MCPsignal PF00015.16 EME28719.1 - 0.1 12.0 0.1 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Apolipoprotein PF01442.13 EME28719.1 - 0.11 11.9 0.2 0.53 9.7 0.0 1.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.6 EME28719.1 - 0.13 12.1 1.2 0.95 9.3 0.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 EME28719.1 - 0.18 11.7 1.6 0.81 9.6 0.2 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 His_Phos_2 PF00328.17 EME28720.1 - 7.9e-40 137.2 0.0 6e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PB1 PF00564.19 EME28720.1 - 0.097 12.3 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 PB1 domain IspD PF01128.14 EME28721.1 - 8.4e-55 185.6 0.0 1e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.2 EME28721.1 - 5.1e-11 42.8 0.0 7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EME28721.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase CTP_transf_3 PF02348.14 EME28721.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF2888 PF11135.3 EME28721.1 - 0.13 11.9 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) Ras PF00071.17 EME28722.1 - 8.7e-43 145.5 0.0 1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME28722.1 - 2.2e-14 53.9 0.0 3.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EME28722.1 - 1.3e-05 24.6 0.0 0.0001 21.7 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EME28722.1 - 6.7e-05 22.1 0.0 8.3e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME28722.1 - 0.0041 17.0 0.0 0.0069 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME28722.1 - 0.16 11.9 0.1 0.34 10.8 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain Acetyltransf_1 PF00583.19 EME28723.1 - 2.7e-08 33.7 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME28723.1 - 0.0019 18.2 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Filament PF00038.16 EME28723.1 - 0.0079 15.6 10.7 0.032 13.7 8.0 1.4 2 0 0 2 2 2 1 Intermediate filament protein Acetyltransf_10 PF13673.1 EME28723.1 - 0.0099 15.9 0.2 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF641 PF04859.7 EME28723.1 - 0.031 14.0 5.5 0.06 13.0 3.8 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.1 EME28723.1 - 0.06 12.3 5.7 0.082 11.8 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.13 EME28723.1 - 0.23 10.9 14.8 0.36 10.3 10.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cortex-I_coil PF09304.5 EME28723.1 - 0.46 10.5 10.2 0.98 9.4 7.1 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF342 PF03961.8 EME28723.1 - 0.56 8.5 5.0 0.8 8.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EME28723.1 - 1.9 6.2 5.2 2.9 5.6 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.6 EME28723.1 - 2 7.6 7.7 3.1 6.9 5.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3498 PF12004.3 EME28723.1 - 2.6 7.0 8.7 3.3 6.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Nbl1_Borealin_N PF10444.4 EME28723.1 - 2.9 7.3 6.7 4.3 6.7 0.3 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Isochorismatase PF00857.15 EME28724.1 - 9e-24 84.3 0.0 1.4e-23 83.6 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Sugar_tr PF00083.19 EME28725.1 - 7.3e-90 301.7 21.4 8.6e-90 301.4 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28725.1 - 1.6e-30 106.0 18.4 1.6e-30 106.0 12.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME28725.1 - 9.8e-05 20.7 1.5 9.8e-05 20.7 1.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_S2 PF00318.15 EME28726.1 - 3.8e-47 160.2 0.0 2.4e-26 92.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S2 PF00318.15 EME28727.1 - 3.7e-47 160.2 0.0 2.1e-26 92.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Gln-synt_C PF00120.19 EME28728.1 - 3.7e-57 193.4 0.0 4.4e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EME28728.1 - 1.2e-13 50.3 0.0 3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Mpv17_PMP22 PF04117.7 EME28729.1 - 1.7e-18 66.0 2.1 2.6e-18 65.3 0.4 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family Latrotoxin_C PF15658.1 EME28729.1 - 0.099 12.4 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Latrotoxin C-terminal domain WD40 PF00400.27 EME28730.1 - 8.1e-18 63.5 7.0 4e-06 26.4 1.3 5.2 6 1 0 6 6 6 3 WD domain, G-beta repeat HSP33 PF01430.14 EME28731.1 - 5.9e-67 225.7 0.0 8.1e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Hsp33 protein PseudoU_synth_2 PF00849.17 EME28732.1 - 7.5e-30 103.9 0.1 1.5e-29 102.9 0.0 1.5 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF98 PF01947.11 EME28732.1 - 0.13 12.0 0.0 6.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF98) CAAD PF14159.1 EME28733.1 - 1.3e-20 72.7 0.1 2.3e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3595 PF12166.3 EME28733.1 - 0.064 12.0 1.7 0.077 11.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF3632 PF12311.3 EME28733.1 - 0.068 12.9 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) RNA_bind PF08675.6 EME28733.1 - 0.093 12.7 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain GAS PF13851.1 EME28734.1 - 0.0046 16.1 33.3 0.041 13.0 0.9 3.9 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding TIR_2 PF13676.1 EME28734.1 - 0.0048 17.0 1.0 0.89 9.7 0.1 2.8 2 1 0 2 2 2 2 TIR domain APG6 PF04111.7 EME28734.1 - 0.52 9.2 30.6 1.4 7.8 10.5 2.6 2 0 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EME28734.1 - 8.9 6.1 41.6 0.35 10.7 6.8 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PsbQ PF05757.6 EME28735.1 - 0.012 15.0 0.1 0.027 13.9 0.1 1.6 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Vma12 PF11712.3 EME28735.1 - 1.3 8.7 9.0 2.6 7.7 6.2 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sulf_transp PF04143.9 EME28736.1 - 1.9e-16 59.8 18.7 5.1e-10 39.2 3.4 4.8 6 0 0 6 6 6 2 Sulphur transport DUF4341 PF14241.1 EME28736.1 - 1.9e-10 40.2 14.1 1.9e-10 40.2 9.8 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) Methyltransf_21 PF05050.7 EME28737.1 - 9.1e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Flavokinase PF01687.12 EME28738.1 - 9.5e-33 112.7 0.0 1.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Myb_DNA-binding PF00249.26 EME28739.1 - 2.1e-48 162.1 20.0 9.2e-16 57.6 0.1 5.2 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28739.1 - 1.2e-41 140.6 12.7 6.5e-15 54.9 0.0 5.5 4 1 2 6 6 6 4 Myb-like DNA-binding domain Rap1_C PF11626.3 EME28739.1 - 0.0041 16.9 0.6 0.073 12.9 0.1 3.0 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 EME28740.1 - 1.8e-48 162.3 20.0 9e-16 57.6 0.1 5.3 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28740.1 - 1.3e-41 140.5 10.7 1.5e-14 53.8 0.0 5.5 4 1 2 6 6 6 4 Myb-like DNA-binding domain Rap1_C PF11626.3 EME28740.1 - 0.0043 16.9 0.6 0.073 12.9 0.1 2.9 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain CCT PF06203.9 EME28741.1 - 1.4e-07 31.0 10.8 2.5e-07 30.2 7.5 1.4 1 1 0 1 1 1 1 CCT motif zf-B_box PF00643.19 EME28741.1 - 0.0006 19.6 10.1 0.0006 19.6 7.0 2.8 3 0 0 3 3 3 1 B-box zinc finger DUF2318 PF10080.4 EME28741.1 - 2.2 8.1 11.8 20 4.9 7.7 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) PHD PF00628.24 EME28741.1 - 4.6 7.0 14.1 1.5 8.5 7.4 2.1 2 0 0 2 2 2 0 PHD-finger Glyco_transf_54 PF04666.8 EME28742.1 - 1.1e-06 27.6 0.2 0.061 12.0 0.0 3.1 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Solute_trans_a PF03619.11 EME28742.1 - 0.012 14.9 0.4 0.017 14.4 0.3 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha PaO PF08417.7 EME28742.1 - 0.061 13.2 0.3 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Pheophorbide a oxygenase KIX PF02172.11 EME28742.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 KIX domain ubiquitin PF00240.18 EME28743.1 - 1.4e-07 30.7 0.1 3.4e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EME28743.1 - 2.5e-06 27.6 0.0 9.5e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EME28743.1 - 0.078 12.6 0.1 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CPDase PF07823.6 EME28743.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein AAA PF00004.24 EME28744.1 - 4.1e-41 140.2 0.0 7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME28744.1 - 1.1e-06 28.8 0.1 0.00015 21.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME28744.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EME28744.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EME28744.1 - 4e-05 23.3 0.1 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EME28744.1 - 8.4e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EME28744.1 - 0.0012 17.9 0.0 0.0028 16.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EME28744.1 - 0.003 16.7 0.1 0.39 9.7 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.1 EME28744.1 - 0.0042 16.5 0.3 0.2 11.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EME28744.1 - 0.0099 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EME28744.1 - 0.01 14.5 0.1 0.021 13.5 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EME28744.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EME28744.1 - 0.015 15.4 0.0 0.083 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EME28744.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EME28744.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EME28744.1 - 0.029 14.0 0.0 0.18 11.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 EME28744.1 - 0.03 14.6 0.1 0.073 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 EME28744.1 - 0.031 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EME28744.1 - 0.045 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EME28744.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME28744.1 - 0.058 13.3 0.6 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EME28744.1 - 0.067 12.4 0.1 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EME28744.1 - 0.078 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EME28744.1 - 0.081 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EME28744.1 - 0.082 13.7 0.6 0.17 12.6 0.1 1.9 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EME28744.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EME28744.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EME28744.1 - 0.15 10.9 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aldedh PF00171.17 EME28745.1 - 1.9e-111 372.6 0.2 2.3e-111 372.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_I_A49 PF06870.7 EME28746.1 - 2.2e-16 59.4 0.1 2.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Lipoprotein_Ltp PF07553.6 EME28746.1 - 0.096 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein RNA_pol_I_A49 PF06870.7 EME28747.1 - 1.7e-31 109.1 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Lipoprotein_Ltp PF07553.6 EME28747.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein AcetylCoA_hyd_C PF13336.1 EME28748.1 - 9.6e-61 203.9 0.0 1.5e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EME28748.1 - 1.5e-27 96.6 0.0 2.8e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.17 EME28748.1 - 0.0029 17.2 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 3 1 DeoR C terminal sensor domain PDZ_2 PF13180.1 EME28749.1 - 2.7e-06 27.1 0.0 0.00056 19.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EME28749.1 - 2.3e-05 24.4 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EME28749.1 - 0.015 15.2 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Pyr_redox_2 PF07992.9 EME28750.1 - 3.6e-28 98.8 0.0 4.4e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME28750.1 - 2.5e-17 63.0 0.6 9.3e-16 58.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME28750.1 - 3.6e-10 40.2 0.0 3.5e-09 37.0 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME28750.1 - 5e-07 29.0 0.3 0.0065 15.5 0.0 3.0 2 1 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EME28750.1 - 2e-05 23.6 1.6 0.13 11.0 0.1 3.7 2 1 2 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.1 EME28750.1 - 2.1e-05 24.4 0.1 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EME28750.1 - 3.5e-05 22.8 0.8 1.9 7.2 0.3 3.8 4 0 0 4 4 4 3 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EME28750.1 - 6.9e-05 23.0 0.1 0.001 19.2 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EME28750.1 - 9.2e-05 21.0 1.0 3.6 5.9 0.0 4.2 5 0 0 5 5 5 2 HI0933-like protein DAO PF01266.19 EME28750.1 - 0.00031 19.7 0.1 3.5 6.4 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME28750.1 - 0.00042 19.5 0.2 0.0044 16.1 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Rhabdo_matrix PF03397.9 EME28750.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein FAD_binding_3 PF01494.14 EME28750.1 - 0.057 12.4 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain La PF05383.12 EME28750.1 - 0.064 13.0 0.0 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 La domain K_oxygenase PF13434.1 EME28750.1 - 0.15 10.9 0.0 0.55 9.0 0.0 1.9 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) CLPTM1 PF05602.7 EME28751.1 - 3.5e-104 348.9 3.7 4.3e-104 348.6 2.6 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EME28751.1 - 0.0031 17.0 4.6 0.0059 16.1 0.5 2.9 3 0 0 3 3 3 1 PQ loop repeat SNARE PF05739.14 EME28752.1 - 5.2e-06 26.0 2.8 6e-06 25.8 1.9 1.1 1 0 0 1 1 1 1 SNARE domain DUF3753 PF12575.3 EME28752.1 - 0.0022 17.7 0.9 0.0032 17.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) Sec20 PF03908.8 EME28752.1 - 0.023 14.3 0.5 0.029 14.0 0.3 1.1 1 0 0 1 1 1 0 Sec20 MCPsignal PF00015.16 EME28752.1 - 0.037 13.5 2.0 0.042 13.3 1.4 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.7 EME28752.1 - 0.055 13.2 0.9 0.062 13.0 0.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF912 PF06024.7 EME28752.1 - 0.088 12.8 0.3 0.094 12.7 0.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BMFP PF04380.8 EME28752.1 - 0.11 12.6 0.5 0.19 11.8 0.3 1.4 1 1 0 1 1 1 0 Membrane fusogenic activity NPV_P10 PF05531.7 EME28752.1 - 0.17 12.1 0.7 0.27 11.5 0.5 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EME28752.1 - 1.2 9.0 5.9 0.15 11.8 1.1 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Radical_SAM PF04055.16 EME28753.1 - 5.2e-12 46.2 0.0 8.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily TMEM141 PF15110.1 EME28753.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TMEM141 protein family Proteasome PF00227.21 EME28754.1 - 1.4e-29 102.7 0.2 1.9e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit ADH_N PF08240.7 EME28755.1 - 4.7e-27 93.8 2.3 1.1e-26 92.6 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME28755.1 - 1.4e-23 82.8 0.2 2.2e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME28755.1 - 0.0031 17.1 0.1 0.006 16.1 0.1 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EME28755.1 - 0.02 14.0 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_8 PF13183.1 EME28755.1 - 0.051 13.5 1.1 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain ELFV_dehydrog PF00208.16 EME28755.1 - 0.14 11.6 0.5 0.23 10.9 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NTP_transf_3 PF12804.2 EME28756.1 - 7.4e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EME28756.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.14 EME28756.1 - 0.00041 19.9 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EME28756.1 - 0.0081 15.8 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase Ribosomal_L27e PF01777.13 EME28757.1 - 4.1e-33 113.3 6.8 5.3e-33 112.9 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EME28757.1 - 3.1e-05 23.5 7.7 0.00015 21.3 5.3 2.2 1 1 0 1 1 1 1 KOW motif Glyco_transf_17 PF04724.8 EME28758.1 - 4.4e-15 55.5 0.0 5.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Sulfotransfer_3 PF13469.1 EME28758.1 - 0.046 14.6 0.6 0.085 13.7 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase family Trypsin_2 PF13365.1 EME28759.1 - 7e-23 80.8 0.7 1.2e-22 80.1 0.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EME28759.1 - 6.6e-17 61.8 0.0 1.3e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EME28759.1 - 1.6e-13 50.3 0.2 4.8e-13 48.8 0.1 1.9 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.4 EME28759.1 - 1.5e-06 26.9 0.2 0.016 13.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.19 EME28759.1 - 0.00033 20.7 1.0 0.0019 18.3 0.3 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) LSM PF01423.17 EME28759.1 - 0.026 14.0 0.1 0.072 12.6 0.1 1.7 1 0 0 1 1 1 0 LSM domain Peptidase_S32 PF05579.8 EME28759.1 - 0.041 12.8 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Exo_endo_phos PF03372.18 EME28760.1 - 6.4e-15 55.7 0.1 8.7e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BCIP PF13862.1 EME28760.1 - 0.0075 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein STIL_N PF15253.1 EME28761.1 - 6.6e-13 48.1 0.0 6.6e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 SCL-interrupting locus protein N-terminus zf-C3HC4_3 PF13920.1 EME28763.1 - 0.015 14.9 13.5 0.029 14.0 9.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28763.1 - 0.13 12.2 18.2 0.29 11.2 12.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME28763.1 - 0.2 11.3 18.3 0.44 10.2 12.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 EME28764.1 - 5.7e-33 114.7 0.4 9e-33 114.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME28764.1 - 2.3e-19 69.8 0.0 1.3e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME28764.1 - 6.5e-14 51.8 0.0 1.6e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME28764.1 - 0.00031 20.2 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 EME28764.1 - 0.0005 19.5 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EME28764.1 - 0.00091 18.8 0.0 0.0052 16.4 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.20 EME28764.1 - 0.003 17.1 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EME28764.1 - 0.0038 16.8 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME28764.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EME28764.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EME28764.1 - 0.027 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 EME28764.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DnaA_N PF11638.3 EME28764.1 - 0.046 13.3 0.5 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 DnaA N-terminal domain Ndr PF03096.9 EME28764.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.7 EME28764.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Sec63 PF02889.11 EME28765.1 - 1e-156 520.9 0.0 4.4e-91 305.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EME28765.1 - 4.4e-41 140.1 0.0 9.1e-29 100.1 0.0 4.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28765.1 - 6.8e-12 45.0 0.0 2.4e-08 33.7 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EME28765.1 - 8.7e-08 32.2 0.0 7.3e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EME28765.1 - 0.00048 19.8 0.0 1.7 8.4 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EME28765.1 - 0.0014 18.7 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EME28765.1 - 0.037 13.9 0.2 13 5.7 0.0 3.4 3 1 1 4 4 4 0 Helicase C-terminal domain IstB_IS21 PF01695.12 EME28765.1 - 0.043 13.2 0.1 1.3 8.4 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein bZIP_1 PF00170.16 EME28766.1 - 2.1e-11 43.6 13.4 2.1e-11 43.6 9.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME28766.1 - 1.3e-06 28.0 12.1 1.3e-06 28.0 8.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper DHC PF09626.5 EME28766.1 - 0.23 12.1 0.7 0.44 11.2 0.5 1.4 1 0 0 1 1 1 0 Dihaem cytochrome c HEAT_2 PF13646.1 EME28767.1 - 1.3e-25 89.5 8.2 5.7e-11 42.5 0.1 8.1 5 4 3 8 8 8 6 HEAT repeats HEAT PF02985.17 EME28767.1 - 3.3e-22 76.5 20.3 7.4e-06 25.6 0.0 11.1 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 EME28767.1 - 5.4e-21 74.4 16.5 7.3e-07 29.4 0.0 10.4 9 2 2 11 11 9 4 HEAT-like repeat MMS19_C PF12460.3 EME28767.1 - 8.8e-08 31.2 5.5 0.016 13.9 0.0 5.0 3 2 2 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 EME28767.1 - 2.6e-07 30.9 1.1 0.096 13.0 0.0 6.5 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EME28767.1 - 3.6e-07 28.9 16.5 1.7e-06 26.6 0.1 6.6 6 2 1 7 7 7 1 Adaptin N terminal region RIX1 PF08167.7 EME28767.1 - 2.9e-06 27.0 3.3 0.13 11.9 0.0 5.6 5 2 1 6 6 6 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EME28767.1 - 0.00015 21.1 9.6 0.25 10.6 0.0 6.8 6 2 2 8 8 8 2 CLASP N terminal DUF2454 PF10521.4 EME28767.1 - 0.00025 20.1 0.6 1.3 8.0 0.1 3.5 2 1 0 3 3 3 2 Protein of unknown function (DUF2454) Arm PF00514.18 EME28767.1 - 0.00072 19.2 6.0 1.6 8.6 0.0 6.1 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EME28767.1 - 0.0008 19.6 2.1 19 6.0 0.0 6.6 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat RasGEF_N_2 PF14663.1 EME28767.1 - 0.02 14.8 1.5 5.6 6.9 0.0 4.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DNA_alkylation PF08713.6 EME28767.1 - 0.024 14.1 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 DNA alkylation repair enzyme Cohesin_HEAT PF12765.2 EME28767.1 - 0.024 14.5 0.3 0.57 10.2 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 EME28767.1 - 0.048 13.5 0.0 2.1 8.3 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) BP28CT PF08146.7 EME28767.1 - 0.087 12.5 0.6 1.5 8.5 0.0 3.4 5 0 0 5 5 4 0 BP28CT (NUC211) domain DUF4456 PF14644.1 EME28767.1 - 1.1 8.4 6.8 4 6.6 0.6 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) Urm1 PF09138.6 EME28768.1 - 9e-32 109.0 0.1 1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EME28768.1 - 0.0016 18.7 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 ThiS family Aminotran_1_2 PF00155.16 EME28769.1 - 3.5e-50 170.9 0.0 1.3e-48 165.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II DEAD PF00270.24 EME28770.1 - 1.7e-19 69.9 0.0 3.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME28770.1 - 8.7e-18 63.9 0.0 2.4e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ran_BP1 PF00638.13 EME28771.1 - 3.4e-17 62.6 0.7 5.1e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 EME28771.1 - 8.8e-08 32.4 15.1 8.8e-08 32.4 10.5 3.0 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Pkinase PF00069.20 EME28772.1 - 3.4e-68 229.5 0.0 3.6e-67 226.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28772.1 - 4.5e-33 114.4 0.1 1.5e-22 79.8 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME28772.1 - 1.5e-07 30.7 0.1 0.0074 15.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EME28772.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EME28772.1 - 0.043 12.8 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FANCI_S2 PF14676.1 EME28773.1 - 1.9e-08 34.3 0.2 1.9e-08 34.3 0.1 3.5 6 0 0 6 6 6 1 FANCI solenoid 2 Sec7 PF01369.15 EME28774.1 - 7.2e-69 231.2 0.9 4e-68 228.8 0.1 2.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EME28774.1 - 1.1e-39 135.5 5.2 1.1e-39 135.5 3.6 3.8 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EME28774.1 - 1.5e-23 82.0 2.7 7.1e-23 79.9 0.5 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.17 EME28774.1 - 0.039 14.0 1.8 1.1 9.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 EME28774.1 - 0.12 12.6 1.8 24 5.3 0.0 4.5 4 1 0 4 4 4 0 HEAT repeats DUF814 PF05670.8 EME28775.1 - 5.3e-09 35.8 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) AAA_11 PF13086.1 EME28775.1 - 0.0098 15.4 2.3 0.013 15.0 1.6 1.2 1 0 0 1 1 1 1 AAA domain TFX_C PF14601.1 EME28775.1 - 0.052 13.3 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term tRNA-synt_1 PF00133.17 EME28776.1 - 1.2e-213 710.5 0.0 1.6e-213 710.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME28776.1 - 6.9e-25 87.5 0.1 3.6e-24 85.2 0.0 2.1 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME28776.1 - 3.9e-16 58.6 1.0 3.8e-05 22.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EME28776.1 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 EME28777.1 - 1.4e-213 710.2 0.0 1.9e-213 709.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME28777.1 - 6.5e-25 87.6 0.1 4e-24 85.1 0.0 2.3 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME28777.1 - 4.8e-16 58.4 0.9 4.2e-05 22.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EME28777.1 - 0.0019 17.3 0.0 0.004 16.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Metallophos PF00149.23 EME28778.1 - 1.1e-40 139.1 0.1 1.5e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 14-3-3 PF00244.15 EME28779.1 - 1.8e-112 374.2 7.0 2.1e-112 373.9 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein HMG_box_5 PF14887.1 EME28779.1 - 0.05 13.3 2.6 0.098 12.4 0.3 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF3106 PF11304.3 EME28779.1 - 0.051 13.9 0.6 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) FlaF PF07309.6 EME28779.1 - 0.068 13.0 0.8 0.33 10.8 0.0 2.3 3 0 0 3 3 3 0 Flagellar protein FlaF TPR_12 PF13424.1 EME28779.1 - 0.21 11.5 1.6 2.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EME28780.1 - 7.7e-31 107.7 0.0 1e-30 107.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME28780.1 - 2.7e-13 49.8 0.0 6.9e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME28780.1 - 1.1e-10 41.4 0.0 2.3e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME28780.1 - 3.9e-06 26.6 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EME28780.1 - 3.4e-05 23.3 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 EME28780.1 - 0.00087 18.2 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EME28780.1 - 0.0022 18.2 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EME28780.1 - 0.0037 16.8 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EME28780.1 - 0.0053 15.5 0.1 0.0087 14.8 0.1 1.3 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.8 EME28780.1 - 0.0073 15.8 1.2 0.039 13.5 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EME28780.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.3 EME28780.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPR_12 PF13424.1 EME28781.1 - 3.9e-08 33.1 4.0 1.7e-07 31.0 1.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME28781.1 - 0.00039 20.7 0.2 0.001 19.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME28781.1 - 0.00047 19.6 0.3 0.0027 17.2 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME28781.1 - 0.001 18.9 0.2 0.0035 17.2 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME28781.1 - 0.0012 18.6 0.4 0.0052 16.6 0.3 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME28781.1 - 0.0021 17.7 2.8 0.0087 15.7 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME28781.1 - 0.012 16.1 0.6 0.046 14.3 0.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME28781.1 - 0.015 14.9 0.5 0.045 13.4 0.4 1.8 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.1 EME28781.1 - 0.081 13.1 0.2 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.11 EME28781.1 - 0.11 11.3 1.0 0.19 10.6 0.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Toxin_2 PF00451.14 EME28783.1 - 0.086 12.9 0.5 0.086 12.9 0.4 3.3 4 0 0 4 4 4 0 Scorpion short toxin, BmKK2 zf-DHHC PF01529.15 EME28787.1 - 6.8 6.0 11.6 9.7 5.5 8.0 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase AAA_22 PF13401.1 EME28788.1 - 0.025 14.7 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain XG_FTase PF03254.8 EME28789.1 - 0.00052 18.6 0.0 0.41 9.0 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase Peptidase_S9 PF00326.16 EME28790.1 - 1.7e-48 164.6 0.1 3.6e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 EME28790.1 - 1.7e-43 148.5 1.3 2.6e-32 111.8 0.1 3.3 3 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 EME28790.1 - 2.9e-08 33.5 0.0 5.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME28790.1 - 8.8e-08 32.2 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EME28790.1 - 7.5e-05 22.2 1.1 0.00017 21.1 0.0 2.0 2 1 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EME28790.1 - 0.00029 20.3 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EME28790.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EME28790.1 - 0.0073 14.8 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EME28790.1 - 0.05 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EME28790.1 - 0.066 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family DUF3141 PF11339.3 EME28790.1 - 0.082 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Xpo1 PF08389.7 EME28791.1 - 1.4e-17 63.9 2.3 1.4e-17 63.9 1.6 4.2 3 2 1 4 4 4 1 Exportin 1-like protein Steroid_dh PF02544.11 EME28792.1 - 9.1e-45 152.0 1.9 9.1e-45 152.0 1.3 2.0 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EME28792.1 - 2.2e-07 30.3 1.1 3.5e-07 29.7 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EME28792.1 - 7.4e-06 26.0 8.7 2.6e-05 24.2 0.5 3.2 3 1 0 3 3 3 2 Phospholipid methyltransferase BPD_transp_1 PF00528.17 EME28793.1 - 4.1e-24 85.1 32.6 9.8e-15 54.5 5.4 4.6 5 0 0 5 5 5 2 Binding-protein-dependent transport system inner membrane component Pigment_DH PF06324.6 EME28793.1 - 0.093 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Abhydrolase_6 PF12697.2 EME28794.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME28794.1 - 0.00041 20.1 0.0 0.00051 19.8 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EME28794.1 - 0.00081 18.7 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EME28795.1 - 1.2e-05 25.3 0.0 1.3e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME28795.1 - 0.00021 21.0 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EME28795.1 - 0.00061 19.1 0.0 0.00079 18.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Na_H_Exchanger PF00999.16 EME28796.1 - 4.8e-69 232.7 35.6 7.2e-69 232.1 24.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spc97_Spc98 PF04130.8 EME28796.1 - 1.8e-31 109.0 17.1 1.2e-30 106.3 11.9 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family TrkA_N PF02254.13 EME28796.1 - 5e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Allatostatin PF05953.7 EME28796.1 - 0.12 12.8 1.1 5.1 7.8 0.1 3.1 2 0 0 2 2 2 0 Allatostatin Na_H_Exchanger PF00999.16 EME28797.1 - 2.7e-69 233.5 39.5 4.1e-69 232.9 27.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Spc97_Spc98 PF04130.8 EME28797.1 - 1.8e-31 109.0 17.1 1.2e-30 106.3 11.9 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family TrkA_N PF02254.13 EME28797.1 - 5e-12 45.8 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Allatostatin PF05953.7 EME28797.1 - 0.13 12.8 1.1 5.1 7.8 0.1 3.1 2 0 0 2 2 2 0 Allatostatin Pro_isomerase PF00160.16 EME28798.1 - 1.8e-23 83.4 0.0 3.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BBP1_N PF15271.1 EME28798.1 - 0.072 13.4 0.5 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein U-box PF04564.10 EME28799.1 - 7.9e-06 25.7 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.26 EME28799.1 - 0.017 15.1 1.8 0.041 13.9 0.2 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain AAA PF00004.24 EME28800.1 - 3.3e-64 215.0 0.0 2.1e-35 121.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME28800.1 - 5.5e-09 36.2 1.0 0.039 14.0 0.4 4.9 4 2 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EME28800.1 - 1.9e-08 35.1 0.0 0.005 17.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.1 EME28800.1 - 6.1e-08 32.6 0.0 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME28800.1 - 2.4e-06 27.3 0.5 0.2 11.3 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EME28800.1 - 3.9e-06 26.0 0.0 0.0022 17.1 0.0 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EME28800.1 - 4.4e-06 25.6 0.1 0.034 12.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EME28800.1 - 5.3e-06 25.9 0.0 0.055 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 EME28800.1 - 2.2e-05 23.3 0.0 0.0041 15.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 EME28800.1 - 3.6e-05 23.8 1.5 0.37 10.7 0.0 3.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EME28800.1 - 0.00054 19.8 0.0 0.37 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME28800.1 - 0.0011 18.6 0.4 0.18 11.6 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA_2 PF07724.9 EME28800.1 - 0.0024 17.8 0.0 0.11 12.4 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 EME28800.1 - 0.011 15.3 0.2 4.7 6.8 0.0 3.1 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.17 EME28800.1 - 0.013 15.6 0.0 9.4 6.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.7 EME28800.1 - 0.017 14.2 0.0 2.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.1 EME28800.1 - 0.019 14.4 0.0 2.8 7.5 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 EME28800.1 - 0.022 13.6 0.0 3.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EME28800.1 - 0.03 14.6 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EME28800.1 - 0.039 13.5 0.1 7.5 6.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EME28800.1 - 0.044 13.3 0.0 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EME28800.1 - 0.062 12.4 0.0 0.72 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EME28800.1 - 0.074 12.4 0.3 46 3.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain Rop PF01815.11 EME28800.1 - 0.087 12.2 0.2 0.26 10.7 0.1 1.8 1 0 0 1 1 1 0 Rop protein ABC_tran PF00005.22 EME28800.1 - 0.16 12.3 0.1 17 5.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EME28800.1 - 0.54 9.8 5.0 8.3 6.0 0.0 3.7 4 0 0 4 4 4 0 NACHT domain DIOX_N PF14226.1 EME28801.1 - 4.1e-07 30.5 0.1 1.1e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME28801.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BRAP2 PF07576.7 EME28802.1 - 1.1e-22 79.6 0.2 3e-22 78.2 0.2 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EME28802.1 - 1.9e-20 72.7 4.0 1.9e-20 72.7 2.7 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EME28802.1 - 2.9e-08 33.4 9.0 2.9e-08 33.4 6.2 2.7 2 0 0 2 2 2 1 Ring finger domain APG6 PF04111.7 EME28802.1 - 0.00025 20.1 30.5 0.00044 19.3 21.1 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C3HC4_3 PF13920.1 EME28802.1 - 0.0025 17.4 19.6 0.0038 16.8 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28802.1 - 0.006 16.5 8.8 0.006 16.5 6.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EME28802.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-rbx1 PF12678.2 EME28802.1 - 0.015 15.3 5.8 0.015 15.3 4.0 2.8 3 1 1 4 4 2 0 RING-H2 zinc finger RRM_6 PF14259.1 EME28802.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1563 PF07599.6 EME28802.1 - 0.029 14.2 1.8 5.8 6.8 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1563) DUF1330 PF07045.6 EME28802.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) DUF4140 PF13600.1 EME28802.1 - 0.19 12.1 12.9 0.99 9.8 2.4 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 EME28802.1 - 0.31 10.7 24.8 0.44 10.2 16.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EME28802.1 - 0.56 9.7 29.9 0.65 9.5 10.0 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EME28802.1 - 0.96 9.3 31.4 2.2 8.1 21.4 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 EME28802.1 - 2 8.6 5.0 2.8e+02 1.8 3.5 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 EME28802.1 - 3.5 7.4 6.6 23 4.8 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF342 PF03961.8 EME28802.1 - 4.7 5.5 20.2 12 4.1 14.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 EME28802.1 - 5.5 6.3 41.0 0.3 10.4 5.3 2.4 2 1 1 3 3 3 0 Intermediate filament protein BRAP2 PF07576.7 EME28803.1 - 9.7e-23 79.8 0.2 3.1e-22 78.2 0.2 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EME28803.1 - 2e-20 72.6 4.0 2e-20 72.6 2.7 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EME28803.1 - 3e-08 33.3 9.0 3e-08 33.3 6.2 2.7 2 0 0 2 2 2 1 Ring finger domain APG6 PF04111.7 EME28803.1 - 0.00027 20.1 30.5 0.00046 19.3 21.1 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C3HC4_3 PF13920.1 EME28803.1 - 0.0027 17.3 19.6 0.004 16.8 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28803.1 - 0.0062 16.5 8.8 0.0062 16.5 6.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EME28803.1 - 0.0067 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-rbx1 PF12678.2 EME28803.1 - 0.013 15.5 5.6 0.013 15.5 3.9 2.8 3 1 1 4 4 2 0 RING-H2 zinc finger RRM_6 PF14259.1 EME28803.1 - 0.015 15.2 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1563 PF07599.6 EME28803.1 - 0.026 14.3 1.6 5.8 6.8 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1563) DUF1330 PF07045.6 EME28803.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) DUF4140 PF13600.1 EME28803.1 - 0.15 12.4 12.4 0.94 9.9 2.3 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 EME28803.1 - 0.54 9.7 29.8 0.63 9.5 9.9 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EME28803.1 - 0.9 9.4 31.2 0.39 10.5 19.5 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 EME28803.1 - 2.2 8.5 5.0 2.8e+02 1.8 3.5 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.5 EME28803.1 - 3.7 7.3 6.6 23 4.8 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF342 PF03961.8 EME28803.1 - 5.9 5.1 20.5 15 3.8 14.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 EME28803.1 - 7.3 5.9 41.3 0.31 10.4 5.3 2.4 2 1 1 3 3 3 0 Intermediate filament protein Rubredoxin PF00301.15 EME28804.1 - 4.4e-05 23.2 2.0 4.4e-05 23.2 1.4 1.9 2 0 0 2 2 2 1 Rubredoxin Zn_Tnp_IS1595 PF12760.2 EME28804.1 - 0.014 15.1 2.2 0.31 10.8 0.0 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EME28804.1 - 0.026 14.4 3.5 0.22 11.4 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 EME28804.1 - 0.082 12.6 0.7 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EME28804.1 - 0.12 12.0 1.1 0.26 10.9 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EME28804.1 - 0.62 9.9 3.8 0.68 9.8 0.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EME28804.1 - 0.79 9.5 3.3 18 5.1 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) C1_1 PF00130.17 EME28804.1 - 1.3 8.7 5.8 2.2 8.0 0.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Eapp_C PF10238.4 EME28804.1 - 1.5 8.6 6.5 0.2 11.5 1.0 2.1 1 1 0 2 2 2 0 E2F-associated phosphoprotein TFIIS_C PF01096.13 EME28804.1 - 1.6 8.3 7.7 2.7 7.7 0.2 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.6 EME28804.1 - 1.7 8.3 5.6 9.1 6.0 1.3 2.8 2 1 2 4 4 4 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.7 EME28804.1 - 2.2 7.7 6.3 5.8 6.3 0.1 2.8 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain TF_Zn_Ribbon PF08271.7 EME28804.1 - 2.3 7.6 7.9 0.42 9.9 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Rubredoxin PF00301.15 EME28805.1 - 4.4e-05 23.2 2.0 4.4e-05 23.2 1.4 1.9 2 0 0 2 2 2 1 Rubredoxin Zn_Tnp_IS1595 PF12760.2 EME28805.1 - 0.014 15.1 2.2 0.31 10.8 0.0 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EME28805.1 - 0.026 14.4 3.5 0.22 11.4 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 EME28805.1 - 0.082 12.6 0.7 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EME28805.1 - 0.12 12.0 1.1 0.26 10.9 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EME28805.1 - 0.62 9.9 3.8 0.68 9.8 0.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EME28805.1 - 0.79 9.5 3.3 18 5.1 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) C1_1 PF00130.17 EME28805.1 - 1.3 8.7 5.8 2.2 8.0 0.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Eapp_C PF10238.4 EME28805.1 - 1.5 8.6 6.5 0.2 11.5 1.0 2.1 1 1 0 2 2 2 0 E2F-associated phosphoprotein TFIIS_C PF01096.13 EME28805.1 - 1.6 8.3 7.7 2.7 7.7 0.2 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.6 EME28805.1 - 1.7 8.3 5.6 9.1 6.0 1.3 2.8 2 1 2 4 4 4 0 Putative transposase DNA-binding domain Desulfoferrod_N PF06397.7 EME28805.1 - 2.2 7.7 6.3 5.8 6.3 0.1 2.8 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain TF_Zn_Ribbon PF08271.7 EME28805.1 - 2.3 7.6 7.9 0.42 9.9 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding HARE-HTH PF05066.8 EME28807.1 - 1.1e-11 44.8 0.0 6.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain zf-HC5HC2H PF13771.1 EME28807.1 - 0.0029 17.6 7.1 0.0029 17.6 4.9 2.9 2 1 0 2 2 2 1 PHD-like zinc-binding domain HD_4 PF13328.1 EME28808.1 - 2.8e-48 163.5 2.0 2.8e-48 163.5 1.4 2.1 3 0 0 3 3 3 1 HD domain RelA_SpoT PF04607.12 EME28808.1 - 1.8e-31 108.5 0.0 9.3e-31 106.2 0.0 2.3 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.17 EME28808.1 - 1.1e-10 41.5 0.2 3.6e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 HD domain TGS PF02824.16 EME28808.1 - 2.5e-08 33.6 0.0 5.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain ACT_6 PF13740.1 EME28808.1 - 0.0052 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EME28808.1 - 0.008 16.4 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain HA PF03457.9 EME28809.1 - 2.2e-47 159.0 23.8 3.5e-11 43.0 0.1 7.9 8 0 0 8 8 8 7 Helicase associated domain Thioredoxin PF00085.15 EME28810.1 - 3.6e-07 29.8 0.0 5.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin FUSC_2 PF13515.1 EME28811.1 - 2.6e-10 40.3 17.8 2.6e-10 40.3 12.3 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EME28811.1 - 6.9e-05 21.4 7.3 6.9e-05 21.4 5.1 2.1 2 0 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 EME28811.1 - 0.0031 16.2 18.0 0.088 11.4 9.3 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter p450 PF00067.17 EME28812.1 - 3.7e-85 286.1 0.3 4.7e-85 285.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ_CXXCXGXG PF00684.14 EME28813.1 - 0.063 13.3 11.0 1.8 8.6 3.2 2.5 1 1 1 2 2 2 0 DnaJ central domain DUF1356 PF07092.7 EME28813.1 - 0.25 10.4 4.0 1.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) zf-HIT PF04438.11 EME28813.1 - 2.4 7.8 8.4 2.9 7.6 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger DZR PF12773.2 EME28813.1 - 4.3 7.2 7.1 5.3 6.9 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.17 EME28814.1 - 1.7e-19 69.2 0.0 2.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28814.1 - 1e-15 57.4 0.0 1.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME28814.1 - 1e-09 38.0 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME28814.1 - 0.1 12.3 1.5 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 DSPc PF00782.15 EME28815.1 - 4.3e-20 71.6 0.1 8.3e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME28815.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EME28815.1 - 0.016 15.2 0.1 0.031 14.3 0.1 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 EME28815.1 - 0.016 14.0 0.1 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase LRR_4 PF12799.2 EME28815.1 - 0.063 12.9 0.7 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) CDKN3 PF05706.7 EME28815.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) ChAPs PF09295.5 EME28816.1 - 3.4e-43 147.8 0.0 7.6e-43 146.7 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EME28816.1 - 5.3e-08 32.8 0.9 0.011 16.3 0.1 4.7 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME28816.1 - 6.9e-08 32.7 0.1 0.0056 16.9 0.0 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME28816.1 - 2.3e-06 28.1 0.2 0.2 12.3 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME28816.1 - 8.6e-06 25.2 0.1 6.2 7.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME28816.1 - 0.00018 21.0 0.0 0.0034 16.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EME28816.1 - 0.00067 19.2 0.0 2.3 8.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME28816.1 - 0.002 18.1 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME28816.1 - 0.018 14.6 0.2 10 5.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME28816.1 - 0.053 13.4 3.5 0.18 11.7 0.2 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Bul1_C PF04426.7 EME28816.1 - 0.65 9.1 8.7 0.076 12.1 2.8 1.7 1 1 1 2 2 2 0 Bul1 C terminus DUF3808 PF10300.4 EME28818.1 - 2.1e-13 49.6 0.0 2.4e-12 46.1 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_14 PF13428.1 EME28818.1 - 1.9e-09 37.3 0.4 9.7 7.1 0.0 7.9 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME28818.1 - 2.3e-09 37.0 1.2 0.002 18.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME28818.1 - 3.3e-05 23.4 3.4 0.24 11.0 0.0 5.3 5 1 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 EME28818.1 - 0.00035 20.2 4.4 42 4.4 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME28818.1 - 0.034 14.3 0.0 11 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME28818.1 - 0.056 13.2 0.5 21 5.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME28818.1 - 2.7 7.7 9.9 4.5 7.0 0.0 5.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME28818.1 - 3.2 7.7 5.2 11 6.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-CCCH PF00642.19 EME28819.1 - 8.2e-12 44.5 26.5 2e-05 24.1 1.5 3.9 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EME28819.1 - 1.9e-09 37.2 5.7 1.9e-09 37.2 3.9 3.5 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EME28819.1 - 2.7e-07 30.1 3.6 2.7e-07 30.1 2.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME28819.1 - 1.4e-05 25.0 6.1 1.4e-05 25.0 4.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME28819.1 - 2.2e-05 24.0 3.1 2.2e-05 24.0 2.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME28819.1 - 4.8e-05 22.9 4.9 4.8e-05 22.9 3.4 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME28819.1 - 0.00046 20.0 5.9 0.00046 20.0 4.1 3.7 4 1 0 4 4 3 1 zinc finger of C3HC4-type, RING Cys_rich_CPXG PF14255.1 EME28819.1 - 0.012 15.4 0.4 0.012 15.4 0.2 1.9 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-RING_UBOX PF13445.1 EME28819.1 - 0.043 13.5 2.6 0.18 11.5 1.8 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EME28819.1 - 0.66 9.7 5.1 0.58 9.9 1.9 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zinc_ribbon_2 PF13240.1 EME28819.1 - 7 6.2 11.0 2.2 7.8 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L11_N PF03946.9 EME28820.1 - 2e-18 65.5 0.3 3.2e-18 64.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EME28820.1 - 1.2e-12 47.7 0.8 2e-12 47.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Methyltransf_4 PF02390.12 EME28821.1 - 2.5e-33 114.8 0.0 3.3e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EME28821.1 - 5.5e-06 26.0 0.0 7.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28821.1 - 1.3e-05 25.7 0.0 1.7e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28821.1 - 0.00029 21.2 0.0 0.00044 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME28821.1 - 0.0069 16.0 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28821.1 - 0.009 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28821.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME28821.1 - 0.037 13.3 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EME28821.1 - 0.1 13.0 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain eIF-1a PF01176.14 EME28822.1 - 1.6e-29 101.0 0.1 2.5e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 AhpC-TSA PF00578.16 EME28823.1 - 4.7e-42 142.5 0.0 5.8e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME28823.1 - 7.7e-22 77.4 0.0 8.9e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.7 EME28823.1 - 0.0071 15.8 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DUF2358 PF10184.4 EME28823.1 - 0.033 14.1 0.1 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) FAM180 PF15173.1 EME28824.1 - 0.055 13.2 0.1 0.065 13.0 0.1 1.1 1 0 0 1 1 1 0 FAM180 family Aldo_ket_red PF00248.16 EME28825.1 - 2.4e-65 220.1 0.0 2.8e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MARVEL PF01284.18 EME28826.1 - 2.7e-06 27.2 16.3 4.1e-06 26.6 11.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain PAH PF02671.16 EME28827.1 - 3.1e-48 161.1 9.2 2.3e-19 68.7 1.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EME28827.1 - 6.4e-39 131.7 0.0 1.7e-38 130.4 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor DUF760 PF05542.6 EME28828.1 - 6.7e-38 128.7 8.4 5.4e-21 74.5 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF760) PBC PF03792.8 EME28828.1 - 0.048 13.3 0.8 0.076 12.6 0.1 1.6 2 0 0 2 2 2 0 PBC domain Pkinase PF00069.20 EME28829.1 - 7e-51 172.8 0.1 1.8e-50 171.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28829.1 - 1.1e-24 86.8 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EME28829.1 - 0.0012 18.1 1.2 0.012 14.9 0.9 2.3 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EME28829.1 - 0.003 16.4 0.1 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EME28829.1 - 0.013 15.0 0.9 0.066 12.7 0.6 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EME28829.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EME28830.1 - 0.00062 19.5 1.3 0.00062 19.5 0.9 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat AAA PF00004.24 EME28831.1 - 1.5e-76 254.9 0.0 1.8e-44 151.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME28831.1 - 1.2e-14 53.9 0.0 5e-07 28.9 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME28831.1 - 8.9e-14 51.7 1.7 7.3e-07 29.3 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME28831.1 - 1.7e-12 47.2 0.1 4.3e-06 26.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME28831.1 - 3.3e-11 43.4 0.8 4.9e-05 23.3 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EME28831.1 - 3.9e-10 40.5 0.0 0.00092 20.0 0.0 3.3 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EME28831.1 - 2.3e-07 30.9 0.0 0.017 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 EME28831.1 - 4.8e-07 29.8 0.0 0.00021 21.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EME28831.1 - 6.3e-07 29.5 0.0 0.005 16.8 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EME28831.1 - 1.2e-06 28.0 0.0 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EME28831.1 - 1.3e-06 28.2 0.0 0.081 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EME28831.1 - 2.6e-06 26.4 0.0 0.012 14.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EME28831.1 - 1.1e-05 24.7 0.1 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EME28831.1 - 1.2e-05 25.2 0.0 0.015 15.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME28831.1 - 1.3e-05 24.7 2.1 0.029 13.7 0.0 3.6 2 2 1 3 3 3 1 AAA domain NACHT PF05729.7 EME28831.1 - 1.9e-05 24.3 0.4 0.1 12.2 0.0 4.0 2 2 1 4 4 4 1 NACHT domain Rad17 PF03215.10 EME28831.1 - 2.1e-05 23.4 0.0 0.016 13.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EME28831.1 - 2.4e-05 24.6 0.0 0.0088 16.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME28831.1 - 2.8e-05 24.1 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EME28831.1 - 9e-05 21.5 0.0 0.064 12.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 EME28831.1 - 9.8e-05 21.9 0.0 0.35 10.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME28831.1 - 0.00016 21.3 0.0 0.012 15.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 EME28831.1 - 0.00027 20.1 0.0 0.18 10.8 0.0 2.9 2 1 0 2 2 2 1 KaiC ABC_tran PF00005.22 EME28831.1 - 0.00037 20.7 0.0 0.13 12.5 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_24 PF13479.1 EME28831.1 - 0.00046 19.8 0.4 0.16 11.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EME28831.1 - 0.0017 18.0 0.1 1.5 8.4 0.0 3.6 2 2 2 4 4 4 1 Archaeal ATPase NB-ARC PF00931.17 EME28831.1 - 0.0021 16.9 0.0 0.061 12.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.12 EME28831.1 - 0.005 15.7 0.0 0.53 9.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 EME28831.1 - 0.0051 16.3 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EME28831.1 - 0.0053 16.6 0.1 5 6.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase Zeta_toxin PF06414.7 EME28831.1 - 0.0059 15.7 0.0 0.48 9.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EME28831.1 - 0.0083 15.8 0.2 0.75 9.4 0.0 3.4 4 0 0 4 4 3 1 NTPase Sigma54_activat PF00158.21 EME28831.1 - 0.0093 15.4 0.0 1.7 8.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain ADK PF00406.17 EME28831.1 - 0.016 15.0 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_11 PF13086.1 EME28831.1 - 0.034 13.7 0.0 0.94 9.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME28831.1 - 0.091 12.3 0.0 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.6 EME28831.1 - 0.095 11.3 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AAA_29 PF13555.1 EME28831.1 - 0.098 12.2 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.1 EME28831.1 - 0.12 12.2 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family PhoH PF02562.11 EME28831.1 - 0.19 10.9 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein HhH-GPD PF00730.20 EME28832.1 - 0.071 13.4 0.0 6.3 7.1 0.0 3.4 3 0 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein HTH_8 PF02954.14 EME28832.1 - 0.084 12.4 0.4 0.94 9.0 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HhH-GPD PF00730.20 EME28833.1 - 0.058 13.6 0.0 6.1 7.1 0.0 3.4 3 0 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein HTH_8 PF02954.14 EME28833.1 - 0.079 12.5 0.4 0.91 9.1 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family PEPCK_ATP PF01293.15 EME28834.1 - 4.2e-07 28.8 0.0 7.1e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribosomal_L38e PF01781.13 EME28835.1 - 1.5e-32 111.1 7.5 1.7e-32 110.9 5.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.12 EME28835.1 - 0.1 12.9 0.4 0.11 12.8 0.3 1.1 1 0 0 1 1 1 0 Early Protein (E6) TFIID_90kDa PF04494.10 EME28835.1 - 0.19 11.7 1.0 0.2 11.7 0.7 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit ADH_N PF08240.7 EME28836.1 - 4.3e-33 113.3 0.9 1.1e-31 108.7 0.4 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME28836.1 - 9.1e-24 83.4 0.0 1.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.19 EME28836.1 - 0.0015 17.4 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME28836.1 - 0.0053 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EME28836.1 - 0.0074 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EME28836.1 - 0.037 12.5 0.0 0.06 11.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein PALP PF00291.20 EME28836.1 - 0.043 13.0 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox PF00070.22 EME28836.1 - 0.19 12.1 0.8 2.2 8.7 0.1 2.9 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase eIF2A PF08662.6 EME28837.1 - 8.7e-69 231.1 0.0 9.5e-68 227.7 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EME28837.1 - 0.0019 18.0 0.5 5.9 6.9 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat DPPIV_N PF00930.16 EME28837.1 - 0.048 12.2 0.3 0.34 9.4 0.0 2.6 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.4 EME28837.1 - 0.11 11.8 0.0 24 4.1 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Neur_chan_memb PF02932.11 EME28838.1 - 0.38 10.6 3.3 0.77 9.5 0.0 2.3 1 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CAP59_mtransfer PF11735.3 EME28839.1 - 5.2e-45 153.5 0.1 6.4e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PseudoU_synth_1 PF01416.15 EME28840.1 - 1.1e-27 96.4 0.0 3.7e-15 56.2 0.0 2.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase AA_kinase PF00696.23 EME28841.1 - 3.6e-36 124.9 0.3 5.1e-36 124.4 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EME28841.1 - 1.2e-22 79.3 2.0 7.3e-22 76.8 0.3 2.4 2 0 0 2 2 2 1 PUA domain YopH_N PF09013.5 EME28841.1 - 0.099 12.3 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 YopH, N-terminal AA_kinase PF00696.23 EME28842.1 - 1.5e-35 122.9 0.3 2.1e-35 122.4 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EME28842.1 - 1.3e-22 79.3 2.0 7.4e-22 76.8 0.3 2.4 2 0 0 2 2 2 1 PUA domain RPE65 PF03055.10 EME28844.1 - 7.2e-119 397.5 0.0 8.6e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_M24 PF00557.19 EME28845.1 - 2.7e-46 157.7 0.4 4.4e-46 157.0 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EME28845.1 - 0.0052 16.6 10.2 0.015 15.2 7.1 1.8 1 0 0 1 1 1 1 MYND finger HNH PF01844.18 EME28846.1 - 4.6e-07 29.6 0.2 7.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.1 EME28846.1 - 0.00035 20.1 0.0 0.0007 19.1 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.18 EME28847.1 - 5.2e-07 29.4 0.2 8.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.1 EME28847.1 - 0.00039 20.0 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Rad21_Rec8_N PF04825.8 EME28848.1 - 6.7e-26 90.4 0.0 1.8e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein S-AdoMet_synt_M PF02772.11 EME28848.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain SRRM_C PF15230.1 EME28848.1 - 0.11 12.5 1.4 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus ABC_tran PF00005.22 EME28849.1 - 9.2e-35 119.9 0.0 2.4e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EME28849.1 - 4.3e-14 53.1 0.0 1.7e-11 44.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain TOBE PF03459.12 EME28849.1 - 2e-09 37.4 0.1 9.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 TOBE domain TOBE_2 PF08402.5 EME28849.1 - 5e-09 36.0 0.0 1.8e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 TOBE domain SMC_N PF02463.14 EME28849.1 - 6.6e-06 25.5 0.0 0.00053 19.2 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain TOBE_3 PF12857.2 EME28849.1 - 2.8e-05 23.8 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 TOBE-like domain AAA_15 PF13175.1 EME28849.1 - 9.8e-05 21.5 0.0 0.35 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EME28849.1 - 0.00024 21.8 0.1 0.0005 20.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME28849.1 - 0.00036 20.0 0.0 0.00073 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EME28849.1 - 0.00037 19.7 0.0 0.00069 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME28849.1 - 0.00046 20.5 0.0 0.00095 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28849.1 - 0.0015 18.6 0.1 0.078 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME28849.1 - 0.0021 17.4 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME28849.1 - 0.0026 17.6 0.2 0.0066 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME28849.1 - 0.0028 17.6 2.6 0.014 15.3 1.8 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EME28849.1 - 0.0038 17.5 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME28849.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EME28849.1 - 0.013 15.6 0.0 0.15 12.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME28849.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EME28849.1 - 0.03 13.9 0.2 0.074 12.7 0.1 1.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 EME28849.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EME28849.1 - 0.036 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_ATPase PF09818.4 EME28849.1 - 0.073 11.6 0.2 5.5 5.4 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 EME28849.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EME28849.1 - 0.11 12.1 0.1 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EME28849.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Alg14 PF08660.6 EME28850.1 - 1.3e-52 178.2 0.4 6.4e-51 172.7 0.3 2.2 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RRM_1 PF00076.17 EME28851.1 - 1.3e-23 82.4 0.0 1.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28851.1 - 2.4e-17 62.6 0.0 3.3e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME28851.1 - 1.1e-09 37.9 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 EME28853.1 - 2.3e-40 138.0 0.0 3.7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EME28853.1 - 1.3e-36 124.5 0.1 2.8e-36 123.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EME28853.1 - 1.8e-10 40.8 0.6 4e-10 39.6 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME28853.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME28853.1 - 0.089 12.6 0.0 0.34 10.7 0.0 1.9 2 1 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 EME28854.1 - 2.3e-40 138.0 0.0 3.7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EME28854.1 - 1.3e-36 124.5 0.1 2.8e-36 123.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EME28854.1 - 1.8e-10 40.8 0.6 4e-10 39.6 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME28854.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME28854.1 - 0.089 12.6 0.0 0.34 10.7 0.0 1.9 2 1 0 2 2 2 0 Dynamin family Peptidase_S41 PF03572.13 EME28855.1 - 4.2e-37 127.1 0.8 9.1e-20 70.7 0.1 3.1 3 0 0 3 3 3 2 Peptidase family S41 PDZ_2 PF13180.1 EME28855.1 - 8.4e-10 38.4 0.1 2.6e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EME28855.1 - 0.00015 21.8 0.1 0.00037 20.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EME28855.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_S41 PF03572.13 EME28856.1 - 4.5e-37 127.0 0.7 9.5e-20 70.6 0.1 3.1 3 0 0 3 3 3 2 Peptidase family S41 PDZ_2 PF13180.1 EME28856.1 - 9.6e-10 38.2 0.1 2.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EME28856.1 - 0.00016 21.7 0.1 0.00039 20.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EME28856.1 - 0.025 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Abhydrolase_6 PF12697.2 EME28857.1 - 4.5e-19 69.2 0.0 5.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME28857.1 - 2e-15 56.8 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME28857.1 - 8e-12 44.8 0.3 1e-09 38.0 0.2 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EME28857.1 - 1e-06 28.5 0.0 6.6e-05 22.5 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EME28857.1 - 2.4e-05 23.8 0.0 0.0002 20.9 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EME28857.1 - 4.6e-05 22.7 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME28857.1 - 0.00038 19.9 0.1 0.084 12.3 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EME28857.1 - 0.0058 16.1 0.0 0.0094 15.4 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EME28857.1 - 0.037 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Mg-por_mtran_C PF07109.6 EME28858.1 - 6e-32 109.5 0.0 1.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_12 PF08242.7 EME28858.1 - 7.6e-13 48.7 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28858.1 - 8.5e-13 48.1 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28858.1 - 3e-12 46.7 0.0 6.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28858.1 - 3.9e-12 46.5 0.0 6.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28858.1 - 9.4e-12 45.5 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28858.1 - 3.1e-10 40.0 0.0 4.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME28858.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME28858.1 - 2.4e-05 23.5 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EME28858.1 - 8.6e-05 22.0 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.13 EME28858.1 - 0.00032 20.3 0.0 0.00088 18.8 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 FmrO PF07091.6 EME28858.1 - 0.00033 19.7 0.0 0.00065 18.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EME28858.1 - 0.00051 19.2 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EME28858.1 - 0.00055 19.6 0.0 0.00085 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EME28858.1 - 0.0012 18.1 0.7 0.97 8.6 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain TehB PF03848.9 EME28858.1 - 0.0059 15.7 0.0 0.026 13.6 0.0 1.8 2 0 0 2 2 2 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.6 EME28858.1 - 0.013 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_PK PF05891.7 EME28858.1 - 0.02 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.5 EME28858.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EME28858.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain SNARE PF05739.14 EME28859.1 - 8.4e-12 44.6 0.2 1.7e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 SNARE domain DUF1241 PF06840.6 EME28859.1 - 0.0027 16.9 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Use1 PF09753.4 EME28859.1 - 0.0028 17.1 0.1 0.0038 16.7 0.1 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 YihI PF04220.7 EME28859.1 - 0.017 14.4 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF3417 PF11897.3 EME28859.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2981 PF11200.3 EME28859.1 - 0.13 11.2 0.3 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) zf-CCHC PF00098.18 EME28860.1 - 6.3e-19 66.9 42.0 2e-07 30.6 1.9 5.7 4 1 1 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 EME28860.1 - 6.2e-08 32.2 30.3 0.0041 16.8 1.5 5.4 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EME28860.1 - 4e-05 23.1 38.0 0.0094 15.5 1.2 5.4 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EME28860.1 - 0.027 13.9 1.2 0.027 13.9 0.8 4.8 3 1 2 5 5 5 0 Zinc knuckle eIF3g PF12353.3 EME28860.1 - 0.089 12.7 0.1 0.089 12.7 0.1 4.3 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G SGL PF08450.7 EME28861.1 - 8.1e-57 192.4 0.1 1.9e-56 191.2 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Proteasome PF00227.21 EME28862.1 - 4.7e-48 163.0 0.1 5.9e-48 162.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EME28862.1 - 0.1 11.8 1.9 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Proteasome beta subunits C terminal Tubulin PF00091.20 EME28863.1 - 4e-74 249.0 0.0 5.7e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME28863.1 - 5.3e-46 155.7 0.0 8e-46 155.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME28863.1 - 9.6e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME28863.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 EME28863.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like AAA PF00004.24 EME28864.1 - 3.8e-42 143.6 0.0 6.5e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME28864.1 - 8.6e-07 28.7 0.0 6.4e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME28864.1 - 1.1e-06 28.7 0.3 2.8e-05 24.1 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME28864.1 - 1.3e-06 28.5 0.0 0.0021 18.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EME28864.1 - 3.9e-06 26.1 0.0 7.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EME28864.1 - 7.2e-06 26.0 0.0 2.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EME28864.1 - 0.00019 22.2 0.4 0.00077 20.2 0.0 2.3 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EME28864.1 - 0.00061 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME28864.1 - 0.00069 19.3 0.1 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EME28864.1 - 0.0011 17.9 0.0 0.0032 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EME28864.1 - 0.0012 17.6 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EME28864.1 - 0.0012 18.9 0.0 0.005 17.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.1 EME28864.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sec8_exocyst PF04048.9 EME28864.1 - 0.0017 18.0 0.5 0.005 16.4 0.4 1.7 2 0 0 2 2 1 1 Sec8 exocyst complex component specific domain DUF4200 PF13863.1 EME28864.1 - 0.0018 18.2 1.7 0.0018 18.2 1.2 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) AAA_18 PF13238.1 EME28864.1 - 0.0019 18.4 0.1 0.0095 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME28864.1 - 0.0037 16.3 0.0 0.01 14.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EME28864.1 - 0.0046 16.1 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 EME28864.1 - 0.0052 15.6 0.0 0.0098 14.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 EME28864.1 - 0.0053 16.1 1.0 0.057 12.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain DUF2951 PF11166.3 EME28864.1 - 0.0061 16.3 0.7 0.015 15.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2951) AAA_3 PF07726.6 EME28864.1 - 0.0079 15.7 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME28864.1 - 0.008 15.6 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EME28864.1 - 0.0082 15.8 0.1 0.035 13.7 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EME28864.1 - 0.0094 15.9 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Laminin_II PF06009.7 EME28864.1 - 0.011 15.4 0.2 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Laminin Domain II NACHT PF05729.7 EME28864.1 - 0.017 14.8 0.0 0.067 12.8 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EME28864.1 - 0.017 14.9 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME28864.1 - 0.018 14.1 0.3 0.1 11.7 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 EME28864.1 - 0.018 14.6 0.1 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 EME28864.1 - 0.02 15.0 1.6 0.059 13.4 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) UPF0079 PF02367.12 EME28864.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EME28864.1 - 0.025 13.8 0.2 0.069 12.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein TPR_MLP1_2 PF07926.7 EME28864.1 - 0.035 13.8 1.1 0.062 13.0 0.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_11 PF13086.1 EME28864.1 - 0.037 13.6 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain GrpE PF01025.14 EME28864.1 - 0.04 13.4 0.5 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 GrpE Sigma54_activ_2 PF14532.1 EME28864.1 - 0.052 13.6 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain ATG16 PF08614.6 EME28864.1 - 0.054 13.3 3.3 0.12 12.2 2.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran PF00005.22 EME28864.1 - 0.091 13.0 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Med4 PF10018.4 EME28864.1 - 0.27 10.5 2.6 0.23 10.8 0.7 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 G-patch PF01585.18 EME28865.1 - 2e-13 49.8 0.1 5.2e-13 48.5 0.1 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EME28865.1 - 2.3e-11 43.2 0.3 5.3e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EME28865.1 - 2.3e-05 24.1 0.9 2.3e-05 24.1 0.6 3.1 2 1 1 3 3 3 1 DExH-box splicing factor binding site R3H PF01424.17 EME28866.1 - 1.9e-11 43.5 0.3 4.3e-11 42.3 0.2 1.7 1 0 0 1 1 1 1 R3H domain DUF1192 PF06698.6 EME28866.1 - 0.069 12.9 0.2 0.23 11.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MARVEL PF01284.18 EME28867.1 - 2.2e-05 24.3 12.3 4.5e-05 23.2 8.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.3 EME28867.1 - 0.0075 16.1 7.5 0.0075 16.1 5.2 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Rubis-subs-bind PF09273.6 EME28868.1 - 9e-18 64.4 0.2 1.9e-17 63.3 0.2 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EME28868.1 - 2e-05 24.9 0.0 9.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 SET domain Chloroa_b-bind PF00504.16 EME28871.1 - 7.6e-41 139.9 0.0 1.2e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2955 PF11168.3 EME28871.1 - 0.027 14.1 0.4 0.047 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) AA_permease PF00324.16 EME28871.1 - 0.084 11.1 0.3 0.16 10.2 0.2 1.4 1 1 0 1 1 1 0 Amino acid permease DUF2201_N PF13203.1 EME28871.1 - 0.33 10.0 3.4 0.42 9.7 2.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF936 PF06075.7 EME28871.1 - 0.41 9.5 11.8 0.52 9.1 8.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ASFV_J13L PF05568.6 EME28871.1 - 0.79 9.2 3.8 0.62 9.5 0.9 1.9 1 1 1 2 2 2 0 African swine fever virus J13L protein Arch_ATPase PF01637.13 EME28872.1 - 0.00013 21.7 0.1 0.0012 18.5 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME28872.1 - 0.16 12.0 0.2 3.5 7.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain PPR PF01535.15 EME28873.1 - 0.0059 16.4 0.5 0.057 13.4 0.0 2.9 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 EME28873.1 - 0.065 13.2 0.3 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 PPR repeat family FMN_red PF03358.10 EME28875.1 - 9.8e-23 80.3 0.0 1.6e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase RNase_H PF00075.19 EME28876.1 - 1.7e-29 102.8 0.0 2.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EME28876.1 - 2.1e-11 43.6 0.2 4.7e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin SNARE_assoc PF09335.6 EME28877.1 - 2.3e-06 27.7 0.8 3.7e-06 27.1 0.2 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein S1FA PF04689.8 EME28877.1 - 0.24 11.3 1.3 2.1 8.2 0.1 2.4 2 1 0 2 2 2 0 DNA binding protein S1FA DUF4271 PF14093.1 EME28877.1 - 0.3 10.7 5.9 2.1 7.9 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) SNARE_assoc PF09335.6 EME28878.1 - 4.8e-18 65.5 3.7 1.4e-17 64.0 2.6 1.9 1 0 0 1 1 1 1 SNARE associated Golgi protein Yos1 PF08571.5 EME28878.1 - 2.2e-12 46.9 0.2 7.6e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Yos1-like DUF1772 PF08592.6 EME28880.1 - 3.7e-20 72.0 5.3 5.8e-20 71.4 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PepSY_TM_2 PF13703.1 EME28880.1 - 0.43 10.7 7.0 0.52 10.5 1.4 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix Adeno_E3B PF03376.9 EME28880.1 - 3.3 7.6 9.0 0.79 9.6 2.9 2.2 2 1 0 2 2 2 0 Adenovirus E3B protein ABC_tran PF00005.22 EME28881.1 - 9.6e-29 100.4 0.2 1.6e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EME28881.1 - 1.7e-20 73.0 18.6 1.3e-19 70.1 12.9 2.1 1 1 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 EME28881.1 - 7.5e-09 35.9 4.7 1.1e-07 32.0 0.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME28881.1 - 6.9e-07 28.8 0.1 6.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28881.1 - 8.5e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EME28881.1 - 1.7e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.14 EME28881.1 - 2e-05 23.9 0.2 4.6e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EME28881.1 - 2e-05 23.8 0.1 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME28881.1 - 9.4e-05 23.2 0.0 0.00024 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME28881.1 - 0.00025 21.1 0.2 0.0012 18.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.1 EME28881.1 - 0.00025 21.4 0.7 0.00048 20.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME28881.1 - 0.00027 20.4 0.8 0.00052 19.4 0.6 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EME28881.1 - 0.00044 20.1 0.0 0.00091 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EME28881.1 - 0.00089 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EME28881.1 - 0.0015 18.8 0.2 0.0052 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME28881.1 - 0.0015 18.0 0.7 0.0078 15.6 0.6 1.9 2 0 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 EME28881.1 - 0.0016 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_15 PF13175.1 EME28881.1 - 0.0017 17.5 0.0 0.12 11.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EME28881.1 - 0.0025 17.5 0.2 0.0073 16.0 0.1 1.9 2 0 0 2 2 1 1 NTPase NB-ARC PF00931.17 EME28881.1 - 0.0026 16.6 0.1 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EME28881.1 - 0.0028 17.3 0.4 0.0068 16.1 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EME28881.1 - 0.003 17.4 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME28881.1 - 0.0033 17.4 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EME28881.1 - 0.0048 16.5 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EME28881.1 - 0.0051 16.4 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EME28881.1 - 0.0055 15.4 0.0 0.011 14.3 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein SSB PF00436.20 EME28881.1 - 0.0057 16.4 0.1 0.019 14.8 0.0 1.9 2 0 0 2 2 1 1 Single-strand binding protein family RNA_helicase PF00910.17 EME28881.1 - 0.0094 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase cobW PF02492.14 EME28881.1 - 0.01 15.2 0.2 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EME28881.1 - 0.013 15.4 0.3 0.027 14.4 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 EME28881.1 - 0.017 15.3 0.5 0.046 13.9 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EME28881.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 EME28881.1 - 0.023 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EME28881.1 - 0.027 13.9 0.1 0.083 12.2 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EME28881.1 - 0.032 14.1 0.1 0.16 11.8 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2075 PF09848.4 EME28881.1 - 0.04 12.8 0.1 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 EME28881.1 - 0.061 13.1 0.1 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.13 EME28881.1 - 0.07 12.5 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PIF1 PF05970.9 EME28881.1 - 0.074 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PduV-EutP PF10662.4 EME28881.1 - 0.088 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_35 PF14516.1 EME28881.1 - 0.095 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EME28881.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EME28881.1 - 0.11 11.2 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EME28881.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 EME28881.1 - 0.15 11.1 0.2 0.26 10.3 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin DUF4131 PF13567.1 EME28881.1 - 2.5 7.4 0.0 2.5 7.4 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) ATP-synt_10 PF05176.9 EME28882.1 - 0.016 14.4 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 ATP10 protein Arf PF00025.16 EME28883.1 - 4.9e-51 172.4 0.0 5.7e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME28883.1 - 3.2e-13 49.3 0.0 4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EME28883.1 - 7.2e-10 39.4 0.0 1e-09 38.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EME28883.1 - 3.4e-07 29.7 0.0 4.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME28883.1 - 5.8e-06 25.2 1.0 0.00073 18.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME28883.1 - 8.9e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME28883.1 - 0.00026 20.8 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME28883.1 - 0.0021 17.5 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF202 PF02656.10 EME28884.1 - 1.7e-14 53.7 1.7 1.7e-14 53.7 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CytB6-F_Fe-S PF08802.5 EME28884.1 - 8.8 6.4 6.0 23 5.0 0.2 2.5 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit SRP54 PF00448.17 EME28885.1 - 6.2e-66 221.5 0.0 9.3e-66 221.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EME28885.1 - 4.9e-13 48.9 0.8 1.1e-12 47.8 0.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 EME28885.1 - 5.5e-06 26.5 1.2 0.00043 20.4 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_31 PF13614.1 EME28885.1 - 0.00013 21.9 0.3 0.72 9.7 0.0 3.0 2 1 0 3 3 3 2 AAA domain CbiA PF01656.18 EME28885.1 - 0.00073 19.0 1.5 0.0021 17.5 0.2 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EME28885.1 - 0.0011 18.0 0.7 0.0074 15.3 0.0 2.3 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_24 PF13479.1 EME28885.1 - 0.005 16.4 0.1 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME28885.1 - 0.0062 16.5 0.1 0.064 13.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EME28885.1 - 0.0094 15.8 0.1 0.035 14.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain BACK PF07707.10 EME28885.1 - 0.01 15.6 0.3 0.021 14.6 0.2 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch AAA_33 PF13671.1 EME28885.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME28885.1 - 0.085 12.2 0.1 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ThiC-associated PF13667.1 EME28885.1 - 0.13 11.8 0.1 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 ThiC-associated domain AAA_25 PF13481.1 EME28885.1 - 0.14 11.5 0.5 1.7 8.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME28885.1 - 0.18 12.0 2.5 1.2 9.4 0.1 2.3 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EME28885.1 - 1.1 9.5 10.2 21 5.3 4.5 2.4 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 EME28885.1 - 1.5 8.0 6.7 4.3 6.5 4.6 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain COPR5 PF15340.1 EME28886.1 - 0.53 10.6 7.4 1 9.6 5.1 1.4 1 0 0 1 1 1 0 Cooperator of PRMT5 family Apt1 PF10351.4 EME28886.1 - 7 5.3 17.4 11 4.7 12.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain AOX PF01786.12 EME28887.1 - 2.7e-83 278.4 0.4 4e-83 277.8 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.8 EME28887.1 - 0.037 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 RcbX PF02341.10 EME28888.1 - 2.8e-05 24.1 1.3 0.14 12.2 0.0 3.5 4 0 0 4 4 4 2 RbcX protein Kinesin PF00225.18 EME28890.1 - 5.3e-100 334.3 1.3 5.3e-100 334.3 0.9 2.5 4 0 0 4 4 4 1 Kinesin motor domain CBM_20 PF00686.14 EME28890.1 - 1.7e-17 62.7 0.3 1.7e-17 62.7 0.2 2.7 3 0 0 3 3 3 1 Starch binding domain PLAT PF01477.18 EME28890.1 - 1.7e-14 54.1 0.3 7.5e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 PLAT/LH2 domain IncA PF04156.9 EME28890.1 - 4.1 6.9 62.8 0.13 11.8 14.7 3.7 3 0 0 3 3 3 0 IncA protein ERM PF00769.14 EME28890.1 - 4.7 6.6 64.2 7.5 6.0 18.0 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Arm PF00514.18 EME28891.1 - 2.6e-81 264.9 8.5 1e-12 47.3 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME28891.1 - 1e-22 80.1 0.0 8.9e-09 35.5 0.0 4.8 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EME28891.1 - 8.6e-20 70.6 1.2 6.9e-07 29.5 0.0 6.0 5 2 3 8 8 7 4 HEAT-like repeat IBB PF01749.15 EME28891.1 - 1.4e-17 63.6 9.3 2.6e-17 62.7 6.4 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EME28891.1 - 3.1e-14 51.7 5.3 1.3e-05 24.8 0.0 7.6 9 0 0 9 9 9 2 HEAT repeat V-ATPase_H_C PF11698.3 EME28891.1 - 1.3e-07 31.5 0.0 0.24 11.3 0.0 4.4 4 0 0 4 4 4 3 V-ATPase subunit H Adaptin_N PF01602.15 EME28891.1 - 1.6e-07 30.0 0.0 0.00013 20.4 0.0 3.0 1 1 2 3 3 3 2 Adaptin N terminal region RICTOR_V PF14668.1 EME28891.1 - 0.00036 20.4 3.6 4.2 7.3 0.0 4.8 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 EME28891.1 - 0.0013 17.8 1.6 1.6 7.8 0.0 3.7 2 1 1 4 4 4 1 Armadillo-like Proteasom_PSMB PF10508.4 EME28891.1 - 0.0021 16.3 0.3 0.063 11.5 0.3 2.6 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF2505 PF10698.4 EME28891.1 - 0.0023 17.4 0.2 7.9 5.9 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2505) CTNNBL PF08216.6 EME28891.1 - 0.0032 17.0 6.3 7.7 6.1 0.0 4.8 5 0 0 5 5 4 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_PBS PF03130.11 EME28891.1 - 0.0041 17.4 0.1 1.6 9.4 0.0 4.1 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Ribosomal_L1 PF00687.16 EME28892.1 - 1.5e-51 174.9 0.0 1.8e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF438 PF04282.8 EME28893.1 - 0.022 14.5 1.7 0.048 13.4 0.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF438) DUF1903 PF08991.5 EME28893.1 - 0.038 14.1 0.4 0.052 13.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Cauli_AT PF03233.8 EME28893.1 - 0.062 13.0 1.2 0.064 12.9 0.8 1.0 1 0 0 1 1 1 0 Aphid transmission protein Cmc1 PF08583.5 EME28893.1 - 0.096 12.4 1.8 0.2 11.4 1.2 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like AATF-Che1 PF13339.1 EME28893.1 - 0.13 12.4 1.0 0.14 12.3 0.7 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Bcr-Abl_Oligo PF09036.5 EME28893.1 - 0.44 10.5 3.0 0.77 9.7 0.2 2.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF948 PF06103.6 EME28894.1 - 0.12 12.2 5.6 0.068 13.0 1.5 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 EME28894.1 - 0.27 11.5 6.3 0.42 10.9 2.7 2.3 2 1 0 2 2 2 0 Spectrin repeat PhaP_Bmeg PF09602.5 EME28894.1 - 3.9 7.2 10.2 6 6.6 2.6 2.5 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3571 PF12095.3 EME28894.1 - 4.8 7.4 6.5 1.3 9.3 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) WD40 PF00400.27 EME28896.1 - 6.3e-29 98.7 10.2 3e-07 30.0 0.1 6.8 6 1 1 7 7 7 6 WD domain, G-beta repeat IKI3 PF04762.7 EME28896.1 - 0.0064 14.3 0.4 0.14 9.9 0.1 2.4 1 1 1 3 3 3 1 IKI3 family Apc4_WD40 PF12894.2 EME28896.1 - 0.19 11.2 1.7 29 4.2 0.0 4.1 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UPF0004 PF00919.15 EME28897.1 - 2.7e-29 100.8 0.1 5.3e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 EME28897.1 - 1.1e-20 74.4 0.0 1.9e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EME28897.1 - 0.044 13.9 0.1 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain LisH PF08513.6 EME28898.1 - 0.01 15.5 0.2 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 LisH Mut7-C PF01927.11 EME28898.1 - 0.018 14.9 0.9 0.033 14.1 0.6 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-C4pol PF14260.1 EME28898.1 - 0.05 13.6 4.4 0.038 13.9 1.4 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Ribosomal_L22 PF00237.14 EME28899.1 - 1.7e-34 117.8 0.1 2.2e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Trp_dioxygenase PF03301.8 EME28900.1 - 7.4e-91 304.8 2.2 9.2e-91 304.5 1.5 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Biopterin_H PF00351.16 EME28902.1 - 1.1e-155 517.4 0.0 1.3e-155 517.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EME28902.1 - 8.1e-06 25.2 0.0 1.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain Aa_trans PF01490.13 EME28903.1 - 9.4e-40 136.3 40.2 1.1e-39 136.1 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EME28903.1 - 4.8e-06 25.4 24.7 4.8e-06 25.4 17.1 2.0 2 1 0 2 2 2 1 Spore germination protein Trp_Tyr_perm PF03222.8 EME28903.1 - 9.8e-05 21.3 19.3 9.8e-05 21.3 13.4 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease PF00324.16 EME28903.1 - 0.49 8.6 41.4 0.0068 14.7 20.0 2.6 1 1 0 2 2 2 0 Amino acid permease Asparaginase_2 PF01112.13 EME28904.1 - 9.2e-83 277.5 0.5 1.1e-82 277.3 0.3 1.0 1 0 0 1 1 1 1 Asparaginase p31comet PF06581.7 EME28904.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding WD40 PF00400.27 EME28905.1 - 6.3e-33 111.4 25.7 5e-08 32.5 0.2 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF4165 PF13752.1 EME28905.1 - 0.13 12.0 0.1 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) DUF2986 PF11661.3 EME28905.1 - 0.22 11.8 0.7 0.48 10.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Snf7 PF03357.16 EME28906.1 - 5.4e-20 71.4 10.9 6.6e-20 71.1 7.6 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EME28906.1 - 1.1e-06 28.1 4.5 1.7e-06 27.5 3.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway hDGE_amylase PF14701.1 EME28906.1 - 0.27 10.0 2.9 0.36 9.6 2.0 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme ELFV_dehydrog PF00208.16 EME28907.1 - 1e-52 179.1 0.4 2.2e-51 174.8 0.0 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EME28907.1 - 3.5e-44 149.5 0.0 6.6e-44 148.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 EME28907.1 - 0.0028 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME28907.1 - 0.0099 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EME28907.1 - 0.022 15.0 0.1 0.075 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EME28907.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 EME28908.1 - 6.3e-53 179.8 0.4 2.2e-51 174.8 0.0 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EME28908.1 - 3.3e-44 149.6 0.0 6.4e-44 148.7 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 EME28908.1 - 0.0027 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME28908.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EME28908.1 - 0.022 15.0 0.1 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EME28908.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Myb_DNA-binding PF00249.26 EME28909.1 - 1.6e-11 44.1 0.3 3.6e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME28909.1 - 0.03 14.4 0.2 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain CN_hydrolase PF00795.17 EME28911.1 - 1.1e-32 112.8 0.0 1.7e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Herpeto_peptide PF14409.1 EME28912.1 - 0.57 9.9 2.0 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Herpetosiphon Ribosomal_S3_C PF00189.15 EME28913.1 - 2.1e-15 56.6 0.1 3.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EME28913.1 - 2.1e-14 52.7 0.0 3.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 KH domain AD PF09793.4 EME28914.1 - 1.3e-23 82.6 0.1 2.2e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain SM-ATX PF14438.1 EME28914.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin6 PF06372.7 EME28914.1 - 0.016 14.5 0.1 0.058 12.7 0.1 1.9 1 1 0 1 1 1 0 Gemin6 protein BRE1 PF08647.6 EME28914.1 - 0.37 10.7 3.9 2.3 8.2 0.6 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Histone PF00125.19 EME28915.1 - 8.8e-27 93.0 0.0 1.1e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME28915.1 - 3.2e-05 23.8 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.6 EME28915.1 - 0.057 13.3 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.19 EME28916.1 - 6e-24 83.9 0.3 8.5e-24 83.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME28916.1 - 1.2e-06 28.4 0.1 2.5e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EME28916.1 - 0.00065 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EME28916.1 - 0.069 12.5 0.1 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 EME28917.1 - 2e-14 53.4 0.5 2.4e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME28917.1 - 5.6e-05 23.2 0.1 9e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EME28917.1 - 0.00016 21.5 0.2 0.00022 21.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EME28917.1 - 0.00026 20.9 0.1 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME28917.1 - 0.0061 16.2 0.1 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EME28917.1 - 0.03 14.0 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EME28917.1 - 0.079 12.2 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NIF PF03031.13 EME28918.1 - 3.1e-44 150.4 0.2 5.5e-44 149.6 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Pex14_N PF04695.8 EME28918.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HAD_2 PF13419.1 EME28918.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FANCI_HD1 PF14679.1 EME28919.1 - 0.063 13.0 0.3 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 Baculo_PEP_C PF04513.7 EME28919.1 - 0.096 12.5 1.4 0.14 11.9 1.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LSM PF01423.17 EME28921.1 - 2.6e-10 39.6 0.2 3.2e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME28921.1 - 0.0046 16.8 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Leo1 PF04004.8 EME28923.1 - 8.2e-27 93.9 0.1 8.2e-27 93.9 0.1 2.3 2 0 0 2 2 2 1 Leo1-like protein Methyltransf_11 PF08241.7 EME28924.1 - 8e-20 71.1 0.0 3.7e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME28924.1 - 4e-16 58.9 0.0 8.7e-16 57.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME28924.1 - 1.9e-15 56.6 0.0 3.5e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME28924.1 - 8.4e-14 51.8 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME28924.1 - 9.2e-14 51.6 0.0 2.8e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28924.1 - 1.1e-13 51.2 0.0 2.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME28924.1 - 4.4e-12 46.5 0.0 1.3e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28924.1 - 2.6e-05 24.2 0.0 5.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME28924.1 - 3.1e-05 23.6 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EME28924.1 - 0.00049 19.5 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EME28924.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EME28924.1 - 0.0044 16.1 0.0 0.0099 14.9 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase COX6B PF02297.12 EME28924.1 - 0.061 13.3 0.2 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0020 PF01170.13 EME28924.1 - 0.069 12.7 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 eRF1_2 PF03464.10 EME28925.1 - 1.8e-41 141.6 0.0 2.8e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EME28925.1 - 1.6e-38 131.4 0.1 4.4e-38 130.0 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EME28925.1 - 1.3e-28 99.2 0.0 3.1e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EME28925.1 - 0.035 13.6 0.0 0.096 12.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2232 PF09991.4 EME28926.1 - 2e-08 33.5 4.2 2e-08 33.5 2.9 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) DUF2232 PF09991.4 EME28927.1 - 2.1e-08 33.5 4.2 2.1e-08 33.5 2.9 1.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) C2 PF00168.25 EME28928.1 - 8.3e-23 80.0 0.0 1.4e-08 34.4 0.0 6.3 7 0 0 7 7 7 3 C2 domain FerI PF08151.7 EME28928.1 - 9.7e-05 22.3 0.0 0.00025 20.9 0.0 1.7 1 0 0 1 1 1 1 FerI (NUC094) domain Rubredoxin PF00301.15 EME28929.1 - 1.1e-06 28.3 2.8 2.6e-06 27.1 2.0 1.7 1 0 0 1 1 1 1 Rubredoxin Zn_Tnp_IS1595 PF12760.2 EME28929.1 - 0.056 13.2 1.8 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EME28929.1 - 0.16 11.2 1.4 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EME28929.1 - 3.1 7.8 6.7 10 6.1 0.2 2.7 1 1 1 2 2 2 0 Zinc ribbon domain TAF1_subA PF14929.1 EME28930.1 - 0.0031 16.0 1.2 0.0058 15.1 0.7 1.6 2 0 0 2 2 2 1 TAF RNA Polymerase I subunit A HTH_25 PF13413.1 EME28930.1 - 0.0072 15.9 0.0 0.022 14.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain DNMT1-RFD PF12047.3 EME28931.1 - 1.9e-12 47.1 0.0 4.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain PHD PF00628.24 EME28931.1 - 1.2e-09 37.6 22.7 3.5e-05 23.3 2.6 3.9 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H_2 PF13832.1 EME28931.1 - 0.00046 20.1 21.0 0.016 15.1 1.9 3.7 1 1 1 3 3 3 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME28931.1 - 0.00086 19.4 22.1 0.46 10.6 3.5 3.9 1 1 2 3 3 3 3 PHD-like zinc-binding domain C1_1 PF00130.17 EME28931.1 - 0.015 14.9 26.8 0.11 12.2 0.1 4.0 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC PF00098.18 EME28931.1 - 0.025 14.5 0.2 0.025 14.5 0.1 2.7 1 1 1 2 2 2 0 Zinc knuckle Thioredoxin PF00085.15 EME28932.1 - 1.3e-30 105.1 0.0 6e-28 96.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EME28932.1 - 1.5e-09 37.9 0.1 3.4e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EME28932.1 - 3.2e-09 36.9 0.1 1.3e-07 31.7 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME28932.1 - 0.00012 22.1 0.4 0.015 15.4 0.0 3.5 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EME28932.1 - 0.0003 20.3 0.0 0.00077 19.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME28932.1 - 0.0019 18.1 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 EME28932.1 - 0.0038 17.1 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EME28932.1 - 0.0052 16.5 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 EME28932.1 - 0.012 15.1 0.0 0.073 12.5 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein HR_lesion PF05514.6 EME28932.1 - 0.07 12.9 0.9 0.29 10.9 0.6 1.9 2 1 0 2 2 2 0 HR-like lesion-inducing Thioredoxin_5 PF13743.1 EME28932.1 - 0.09 12.3 0.0 2.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.5 EME28932.1 - 0.1 12.1 0.0 0.56 9.7 0.0 2.0 2 0 0 2 2 2 0 Redoxin Complex1_LYR PF05347.10 EME28933.1 - 2e-11 43.4 1.1 2e-11 43.4 0.8 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME28933.1 - 7.6e-11 42.0 0.6 1.5e-10 41.1 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like PrmA PF06325.8 EME28934.1 - 2.7e-60 204.0 0.0 3.2e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EME28934.1 - 1.6e-08 34.2 0.2 3.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME28934.1 - 4.8e-07 29.3 0.0 7.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EME28934.1 - 4.7e-06 27.1 0.0 9.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME28934.1 - 2.7e-05 24.1 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME28934.1 - 0.0001 22.0 0.0 0.00023 20.9 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME28934.1 - 0.00093 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EME28934.1 - 0.0039 16.5 0.2 0.014 14.7 0.1 1.8 1 1 1 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 EME28934.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rad21_Rec8_N PF04825.8 EME28935.1 - 4.2e-35 120.0 0.0 8.7e-35 119.0 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EME28935.1 - 1.4e-11 43.3 0.3 4.8e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EME28935.1 - 0.00025 20.7 0.6 0.00068 19.2 0.4 1.7 1 0 0 1 1 1 1 ScpA/B protein DnaJ PF00226.26 EME28936.1 - 9.1e-15 54.1 0.2 1.7e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain PI3_PI4_kinase PF00454.22 EME28937.1 - 4.7e-35 121.1 0.0 6.8e-34 117.3 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EME28937.1 - 1.5e-10 40.5 1.1 3.3e-10 39.4 0.2 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Hydrolase_6 PF13344.1 EME28938.1 - 5.2e-13 48.7 0.0 1.1e-11 44.5 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME28938.1 - 3.2e-12 45.9 0.0 5.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME28938.1 - 0.0024 18.2 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME28938.1 - 0.042 14.0 0.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME28939.1 - 2.8e-17 62.4 0.0 3.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME28939.1 - 0.02 15.3 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME28940.1 - 7.8e-13 47.9 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like WH1 PF00568.18 EME28942.1 - 0.00098 18.8 0.2 0.0023 17.6 0.1 1.7 1 0 0 1 1 1 1 WH1 domain DUF2982 PF11201.3 EME28943.1 - 0.049 12.9 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) Arch_ATPase PF01637.13 EME28944.1 - 0.0024 17.6 0.0 0.0084 15.8 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase DUF1654 PF07867.6 EME28944.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Aa_trans PF01490.13 EME28947.1 - 2.9e-08 32.6 2.5 3.2e-08 32.4 1.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPX PF03105.14 EME28948.1 - 5.9e-29 101.7 13.5 2.7e-14 53.6 0.1 2.6 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.14 EME28948.1 - 5.4e-25 88.2 38.7 1e-24 87.2 26.8 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EME28948.1 - 7.1e-16 57.7 16.8 7.1e-16 57.7 11.7 2.5 1 1 1 3 3 3 2 Citrate transporter DctM PF06808.7 EME28948.1 - 0.0039 15.8 26.9 0.0067 15.0 9.7 2.3 2 0 0 2 2 2 2 DctM-like transporters DUF4371 PF14291.1 EME28948.1 - 0.12 11.9 1.0 0.33 10.4 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4371) ATPase_gene1 PF09527.5 EME28948.1 - 1.3 8.8 14.2 0.49 10.2 0.6 4.3 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) NMO PF03060.10 EME28949.1 - 8e-71 238.8 0.0 9.1e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EME28949.1 - 4.5e-06 25.8 0.0 0.00048 19.1 0.0 2.3 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.12 EME28949.1 - 0.00023 20.3 0.0 0.0016 17.6 0.0 2.0 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 EME28949.1 - 0.00097 18.4 0.1 0.0086 15.3 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.13 EME28949.1 - 0.0019 17.1 0.0 0.0043 15.9 0.0 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EME28949.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF561 PF04481.7 EME28949.1 - 0.002 17.1 0.1 0.004 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF561) PcrB PF01884.12 EME28949.1 - 0.03 13.5 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 PcrB family WD40 PF00400.27 EME28950.1 - 6.8e-56 184.2 22.3 1.4e-10 40.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EME28950.1 - 1e-14 54.4 9.2 2.2e-14 53.4 6.4 1.6 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EME28950.1 - 0.0031 15.8 2.3 0.042 12.1 0.1 3.0 2 2 2 4 4 4 1 Cytochrome D1 heme domain Filament PF00038.16 EME28950.1 - 0.018 14.4 5.9 0.03 13.8 4.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein TMF_DNA_bd PF12329.3 EME28950.1 - 0.071 12.9 8.6 0.16 11.7 6.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EME28950.1 - 0.072 13.0 8.6 0.18 11.7 5.9 1.7 1 0 0 1 1 1 0 FlxA-like protein Spc7 PF08317.6 EME28950.1 - 0.21 10.2 6.7 0.31 9.6 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pinin_SDK_memA PF04696.8 EME28950.1 - 0.45 10.1 5.1 0.87 9.1 3.6 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TPR_MLP1_2 PF07926.7 EME28950.1 - 2 8.1 10.6 1.2 8.9 5.8 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EME28950.1 - 2.4 5.9 4.1 3.3 5.4 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EME28950.1 - 6.2 6.3 7.0 9.8 5.7 4.9 1.2 1 0 0 1 1 1 0 IncA protein Acetyltransf_7 PF13508.1 EME28951.1 - 6.7e-12 45.4 0.1 3e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME28951.1 - 6.6e-07 29.4 0.4 2.1e-06 27.8 0.0 2.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyoxalase_2 PF12681.2 EME28951.1 - 6.1e-06 26.8 0.1 4.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain Acetyltransf_1 PF00583.19 EME28951.1 - 7e-06 25.9 0.4 1.4e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EME28951.1 - 0.00011 22.0 0.3 0.00093 19.0 0.2 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 EME28951.1 - 0.0013 18.6 0.5 0.0054 16.7 0.1 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FR47 PF08445.5 EME28951.1 - 0.0029 17.3 0.3 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Ribosomal_S25 PF03297.10 EME28952.1 - 4e-36 123.2 0.5 4.5e-36 123.0 0.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Actin PF00022.14 EME28953.1 - 1.7e-156 520.5 0.0 2e-156 520.3 0.0 1.0 1 0 0 1 1 1 1 Actin BAG PF02179.11 EME28954.1 - 1.5e-06 28.1 1.5 1.5e-06 28.1 1.1 1.9 2 0 0 2 2 2 1 BAG domain IQ PF00612.22 EME28954.1 - 0.0054 16.2 0.3 0.012 15.2 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Muted PF14942.1 EME28954.1 - 0.23 11.3 6.0 0.11 12.3 0.8 2.4 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Baculo_p24 PF05073.7 EME28954.1 - 1.8 8.0 6.0 0.63 9.5 1.3 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Iso_dh PF00180.15 EME28955.1 - 5.8e-132 439.8 0.0 6.8e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 EME28956.1 - 5.1e-132 440.0 0.0 5.9e-132 439.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BSD PF03909.12 EME28957.1 - 3e-05 23.6 0.1 6.9e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 BSD domain PCI PF01399.22 EME28958.1 - 7.9e-12 45.4 0.9 2.6e-11 43.7 0.6 1.9 1 0 0 1 1 1 1 PCI domain ORC5_C PF14630.1 EME28958.1 - 0.0067 15.9 0.5 0.14 11.5 0.1 2.2 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Ku_PK_bind PF08785.6 EME28958.1 - 0.032 14.1 1.5 0.22 11.4 0.0 3.0 2 1 1 3 3 3 0 Ku C terminal domain like PRK PF00485.13 EME28958.1 - 0.15 11.5 0.6 0.5 9.9 0.3 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UPF0122 PF04297.9 EME28958.1 - 0.22 11.5 2.8 0.26 11.3 0.2 2.3 2 1 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Molybdopterin PF00384.17 EME28959.1 - 3.3e-55 187.5 0.0 2.3e-54 184.8 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 EME28959.1 - 2e-14 53.4 0.1 5.1e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1982) TPP_enzyme_M PF00205.17 EME28959.1 - 0.16 11.6 0.0 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Voltage_CLC PF00654.15 EME28960.1 - 1.5e-59 201.8 26.6 1.5e-59 201.8 18.4 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EME28960.1 - 0.024 14.4 2.0 0.21 11.3 0.0 2.7 3 0 0 3 3 3 0 CBS domain Ribosomal_L20 PF00453.13 EME28961.1 - 7e-20 70.9 0.3 9e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 HRDC PF00570.18 EME28961.1 - 0.081 12.6 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 HRDC domain Pox_MCEL PF03291.11 EME28962.1 - 0.00042 19.2 0.0 0.00055 18.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme DUF4613 PF15390.1 EME28962.1 - 0.007 14.6 0.1 0.011 13.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) DUF230 PF03003.11 EME28962.1 - 0.078 12.5 3.6 0.13 11.7 2.5 1.3 1 0 0 1 1 1 0 Poxvirus proteins of unknown function Rdx PF10262.4 EME28962.1 - 0.082 12.9 0.8 2.6 8.1 0.9 2.6 2 1 0 2 2 2 0 Rdx family Chorein_N PF12624.2 EME28963.1 - 8.4e-07 28.5 0.2 3.2e-06 26.6 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Alpha_kinase PF02816.13 EME28964.1 - 1.6e-34 119.2 3.1 6.1e-31 107.5 0.2 2.1 2 0 0 2 2 2 2 Alpha-kinase family RRM_1 PF00076.17 EME28965.1 - 2.3e-29 100.8 0.0 7.4e-17 60.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28965.1 - 2.8e-23 81.6 0.0 1.8e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME28965.1 - 4.9e-15 55.1 0.0 1.4e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME28965.1 - 0.0019 18.0 0.1 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 EME28965.1 - 0.043 13.5 0.3 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Limkain b1 Rhomboid PF01694.17 EME28966.1 - 3.6e-23 82.2 13.0 3.6e-23 82.2 9.0 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EME28966.1 - 0.015 15.6 1.9 0.015 15.6 1.3 2.9 1 1 2 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) She9_MDM33 PF05546.6 EME28966.1 - 0.066 12.7 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family Sigma70_r2 PF04542.9 EME28967.1 - 1.7e-15 56.4 0.0 3.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EME28967.1 - 6.3e-08 31.8 2.1 8.7e-07 28.1 0.2 3.1 3 1 1 4 4 4 1 Sigma-70, region 4 Sigma70_r3 PF04539.11 EME28967.1 - 1.7e-05 24.6 1.0 0.3 10.9 0.0 3.2 4 0 0 4 4 4 2 Sigma-70 region 3 Sigma70_r1_2 PF00140.15 EME28967.1 - 0.11 12.1 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Gly_transf_sug PF04488.10 EME28968.1 - 3.5e-11 43.4 0.0 7.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EME28968.1 - 1.6e-05 23.6 0.0 2.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EME28968.1 - 0.00055 19.1 0.0 0.00098 18.3 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DDR PF08841.5 EME28968.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Sugar_tr PF00083.19 EME28969.1 - 2.7e-86 289.9 32.7 3.2e-86 289.7 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME28969.1 - 8e-26 90.5 42.2 4.9e-15 55.0 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME28969.1 - 0.0033 15.8 28.7 0.0095 14.3 4.9 3.1 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EME28969.1 - 0.026 14.3 0.9 0.026 14.3 0.6 3.5 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 EME28969.1 - 1.8 6.5 13.8 0.044 11.8 4.7 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Glycos_transf_1 PF00534.15 EME28970.1 - 2.2e-12 46.7 0.0 2.8e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME28970.1 - 4.3e-08 33.3 0.0 8.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 STT3 PF02516.9 EME28971.1 - 1.8e-104 350.4 41.2 2.8e-104 349.7 28.6 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit UPF0029 PF01205.14 EME28973.1 - 2.1e-21 75.6 0.0 3.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1528 PF07515.6 EME28973.1 - 0.081 12.9 0.1 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1528) SpoU_methylase PF00588.14 EME28974.1 - 3.6e-28 98.2 0.0 5.4e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family UPF0029 PF01205.14 EME28974.1 - 1.4e-25 89.1 0.0 3.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Mito_carr PF00153.22 EME28975.1 - 6.3e-69 227.7 1.2 1.1e-22 79.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein VHS PF00790.14 EME28976.1 - 2.6e-24 85.4 0.6 6.1e-24 84.2 0.1 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EME28976.1 - 1.7e-11 44.0 2.2 3.4e-11 42.9 0.8 2.2 2 0 0 2 2 2 1 GAT domain WD40 PF00400.27 EME28977.1 - 1.5e-46 154.6 19.9 9.8e-10 37.9 0.2 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME28977.1 - 8.8e-05 20.8 9.7 0.0051 15.0 0.1 4.3 3 2 2 5 5 5 2 Nucleoporin Nup120/160 CCDC155 PF14662.1 EME28977.1 - 0.011 15.3 6.8 0.017 14.6 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 EME28977.1 - 0.038 13.0 5.4 0.066 12.2 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 EME28977.1 - 0.087 12.7 2.2 0.14 12.0 1.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 EME28977.1 - 0.12 12.2 4.3 0.22 11.4 3.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Vip3A_N PF12495.3 EME28977.1 - 0.12 12.0 0.5 0.27 10.8 0.2 1.6 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF4600 PF15372.1 EME28977.1 - 0.15 12.2 5.1 0.3 11.3 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF2353 PF09789.4 EME28977.1 - 0.17 11.1 8.0 0.28 10.3 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4200 PF13863.1 EME28977.1 - 0.18 11.7 8.5 0.29 11.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nup54 PF13874.1 EME28977.1 - 0.34 10.5 3.8 0.59 9.7 2.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 EME28977.1 - 1.5 9.1 5.6 10 6.5 3.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EME28977.1 - 1.9 8.0 9.4 3.2 7.3 6.5 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EME28977.1 - 3 7.3 14.6 0.63 9.5 0.3 3.2 1 1 2 3 3 3 0 Septum formation initiator TBPIP PF07106.8 EME28977.1 - 3.3 7.2 7.7 5.7 6.4 4.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EME28977.1 - 4.2 7.4 8.8 4.2 7.4 2.2 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Suppressor_APC PF11414.3 EME28977.1 - 6.2 6.6 9.3 5.8 6.7 1.5 2.2 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF3086 PF11285.3 EME28977.1 - 7.8 5.2 9.2 1.9 7.2 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Grp1_Fun34_YaaH PF01184.14 EME28978.1 - 7.8e-34 116.8 18.5 1e-33 116.4 12.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1118 PF06549.7 EME28978.1 - 0.028 14.5 1.4 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Kelch_5 PF13854.1 EME28978.1 - 0.028 14.3 0.6 0.36 10.8 0.1 2.5 2 0 0 2 2 2 0 Kelch motif UQ_con PF00179.21 EME28979.1 - 5.9e-40 135.9 0.0 6.6e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME28979.1 - 0.024 14.5 0.1 0.041 13.7 0.0 1.3 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EME28979.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DASH_Dad1 PF08649.5 EME28980.1 - 0.06 13.0 0.3 2.2 8.0 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 DASH_Dad1 PF08649.5 EME28981.1 - 0.025 14.2 0.6 1.8 8.2 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 PSII_Pbs27 PF13326.1 EME28982.1 - 1.9e-31 109.0 0.0 2.1e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Photosystem II Pbs27 TAT_signal PF10518.4 EME28982.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence 7TM_GPCR_Srd PF10317.4 EME28982.1 - 0.027 13.4 0.2 0.042 12.8 0.0 1.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd CDT1 PF08839.6 EME28983.1 - 1e-10 41.8 0.2 1e-10 41.8 0.1 2.1 2 1 0 2 2 2 1 DNA replication factor CDT1 like DUF4521 PF15021.1 EME28983.1 - 0.004 16.7 2.6 0.004 16.7 1.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4521) PC4 PF02229.11 EME28983.1 - 0.063 12.5 0.2 0.18 11.0 0.2 1.7 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) DUF2839 PF10999.3 EME28983.1 - 0.44 10.6 5.0 13 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) RRM_1 PF00076.17 EME28984.1 - 1.1e-14 53.8 0.0 1.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME28984.1 - 1.6e-12 47.2 0.0 2.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME28984.1 - 2.8e-07 30.2 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3791 PF12668.2 EME28984.1 - 0.13 11.8 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Syntaxin-6_N PF09177.6 EME28985.1 - 1.8e-23 82.7 1.9 1.8e-23 82.7 1.3 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EME28985.1 - 1.4e-08 34.3 5.6 2.4e-08 33.5 0.9 3.1 3 0 0 3 3 3 1 SNARE domain Vip3A_N PF12495.3 EME28985.1 - 0.011 15.3 0.3 0.042 13.5 0.0 1.9 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal DUF745 PF05335.8 EME28985.1 - 0.34 10.4 4.0 5.9 6.3 0.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Baculo_p24 PF05073.7 EME28985.1 - 1.3 8.5 7.2 0.29 10.6 0.3 2.3 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF3571 PF12095.3 EME28985.1 - 1.6 9.0 4.9 1.3 9.3 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3571) ACCA PF03255.9 EME28985.1 - 1.6 8.2 5.3 0.35 10.4 0.3 2.2 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Snapin_Pallidin PF14712.1 EME28986.1 - 7.1e-08 32.6 0.4 9e-08 32.3 0.3 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Laminin_II PF06009.7 EME28986.1 - 0.0075 16.0 1.1 0.0085 15.8 0.7 1.1 1 0 0 1 1 1 1 Laminin Domain II Dor1 PF04124.7 EME28986.1 - 0.038 12.4 0.4 0.044 12.2 0.3 1.0 1 0 0 1 1 1 0 Dor1-like family Gly_transf_sug PF04488.10 EME28986.1 - 0.15 12.4 0.1 3.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif Vac_Fusion PF02346.11 EME28986.1 - 0.17 11.3 1.7 1.8 8.0 0.2 2.3 1 1 1 2 2 2 0 Chordopoxvirus fusion protein SlyX PF04102.7 EME28986.1 - 0.39 11.1 1.9 3.7 7.9 0.1 2.1 1 1 1 2 2 2 0 SlyX CENP-F_leu_zip PF10473.4 EME28986.1 - 2.7 7.8 7.5 16 5.3 5.0 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sulfate_transp PF00916.15 EME28987.1 - 9.9e-54 182.2 13.4 2.5e-53 180.8 9.3 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EME28987.1 - 4.1e-17 61.6 0.9 4.1e-17 61.6 0.6 4.1 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EME28987.1 - 4.7e-05 22.7 0.0 8.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF2583 PF10762.4 EME28987.1 - 2.7 8.2 9.3 3.9 7.6 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Vps36_ESCRT-II PF11605.3 EME28988.1 - 0.00029 20.5 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 EME28988.1 - 0.0049 17.0 0.0 0.0056 16.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain GRAM PF02893.15 EME28988.1 - 0.02 14.3 0.0 0.056 12.9 0.0 1.7 1 1 1 2 2 2 0 GRAM domain Vps36_ESCRT-II PF11605.3 EME28989.1 - 0.00028 20.6 0.0 0.00051 19.8 0.0 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 CCER1 PF15482.1 EME28989.1 - 0.00085 19.0 0.1 0.0011 18.7 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 bPH_3 PF14470.1 EME28989.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain GRAM PF02893.15 EME28989.1 - 0.046 13.2 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 GRAM domain PCNA_N PF00705.13 EME28990.1 - 4.9e-53 177.9 1.7 9.3e-53 177.0 1.1 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EME28990.1 - 1.7e-47 160.5 0.1 1.2e-46 157.7 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EME28990.1 - 7.8e-07 28.1 0.3 9.8e-06 24.5 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EME28990.1 - 1.9e-05 23.9 0.1 2.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EME28990.1 - 0.0057 15.6 0.1 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Hus1-like protein PTCB-BRCT PF12738.2 EME28991.1 - 4.3e-43 145.0 7.9 1.8e-16 59.7 0.0 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 EME28991.1 - 1.4e-29 102.0 5.5 1.3e-09 38.0 0.0 5.5 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain E1-E2_ATPase PF00122.15 EME28993.1 - 1e-29 103.2 1.2 3.6e-29 101.4 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EME28993.1 - 1.3e-26 94.3 0.0 2.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME28993.1 - 1.4e-10 41.7 0.0 2.8e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME28993.1 - 0.0001 22.0 0.4 0.018 14.6 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EME28994.1 - 3.8e-26 91.6 8.1 4.9e-26 91.2 5.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME28994.1 - 0.00081 17.8 11.3 0.47 8.7 4.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EME28994.1 - 0.0044 15.6 3.2 0.0044 15.6 2.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter LacY_symp PF01306.14 EME28994.1 - 0.0068 15.0 15.5 0.0076 14.8 0.5 2.5 2 1 0 2 2 2 2 LacY proton/sugar symporter Pkinase PF00069.20 EME28995.1 - 2.3e-79 266.2 0.0 3.5e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28995.1 - 3.6e-43 147.5 0.0 5.3e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME28995.1 - 1.4e-09 37.3 0.0 2e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like UBA PF00627.26 EME28995.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain APH PF01636.18 EME28995.1 - 0.029 14.1 0.1 0.062 13.0 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EME28995.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EME28996.1 - 1.3e-79 267.0 0.0 1.9e-79 266.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME28996.1 - 2e-43 148.3 0.0 2.9e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME28996.1 - 7.2e-10 38.2 0.0 1.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like UBA PF00627.26 EME28996.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain APH PF01636.18 EME28996.1 - 0.021 14.5 0.1 0.047 13.4 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EME28996.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CPSase_L_D3 PF02787.14 EME28996.1 - 0.09 12.5 0.2 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain UBA_2 PF08587.6 EME28996.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DNA_ligase_A_M PF01068.16 EME28997.1 - 3.6e-47 160.3 0.0 6.3e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME28997.1 - 1.5e-40 138.8 0.1 3e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME28997.1 - 9e-09 35.6 0.0 3.1e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EME28997.1 - 0.00011 21.9 0.3 0.051 13.2 0.1 3.2 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain DUF3885 PF13021.1 EME28997.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) SYF2 PF08231.7 EME28998.1 - 2.1e-27 96.1 11.6 2.1e-27 96.1 8.0 2.1 2 0 0 2 2 2 1 SYF2 splicing factor TMEM151 PF14857.1 EME28998.1 - 0.098 11.2 0.2 0.18 10.3 0.1 1.4 1 0 0 1 1 1 0 TMEM151 family Peptidase_M17_N PF02789.12 EME28998.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain DUF972 PF06156.8 EME28999.1 - 0.15 12.4 3.1 0.19 12.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MRP-S28 PF10213.4 EME29000.1 - 0.0013 18.8 0.0 0.0041 17.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Med19 PF10278.4 EME29000.1 - 0.75 9.4 0.0 0.75 9.4 0.0 2.3 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF1764 PF08576.5 EME29000.1 - 6.9 7.5 8.4 12 6.7 5.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3727 PF12527.3 EME29002.1 - 2.5e-16 59.5 3.3 2.2e-14 53.3 0.4 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3727) DUF1292 PF06949.6 EME29002.1 - 1.2e-08 35.2 6.0 1.8e-08 34.6 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1292) Cyclin_N PF00134.18 EME29003.1 - 1.2e-17 63.6 0.9 8.4e-17 60.9 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME29003.1 - 0.00041 20.2 0.4 0.00041 20.2 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EME29003.1 - 0.1 12.4 0.1 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF21 PF01595.15 EME29004.1 - 2e-31 108.7 3.1 2.9e-31 108.1 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME29004.1 - 9.8e-16 57.2 0.4 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF21 PF01595.15 EME29005.1 - 2.6e-31 108.3 3.6 3.9e-31 107.7 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME29005.1 - 9.7e-16 57.2 0.4 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain GCV_H PF01597.14 EME29006.1 - 0.054 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein HMG-CoA_red PF00368.13 EME29007.1 - 2.5e-153 510.1 0.5 3e-153 509.8 0.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase SR-25 PF10500.4 EME29007.1 - 0.04 13.3 1.7 0.062 12.7 1.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyltransferase PF01553.16 EME29008.1 - 3.3e-16 58.9 0.0 5.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MtrG PF04210.8 EME29008.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G BLOC1_2 PF10046.4 EME29010.1 - 0.029 14.4 4.8 0.047 13.8 0.0 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 EME29010.1 - 0.044 13.2 3.4 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 EME29010.1 - 0.15 12.3 3.3 5.9 7.2 0.0 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EME29010.1 - 0.21 11.5 9.9 0.85 9.6 4.3 2.9 2 0 0 2 2 2 0 FlxA-like protein Allexi_40kDa PF05549.6 EME29010.1 - 0.39 9.9 7.7 1.5 8.0 0.1 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 EME29010.1 - 1.6 8.8 9.0 0.8 9.8 0.1 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RP-C_C PF11800.3 EME29010.1 - 1.7 8.3 8.8 0.27 10.9 0.1 2.5 2 1 0 2 2 2 0 Replication protein C C-terminal region AbiH PF14253.1 EME29010.1 - 5.6 6.4 11.3 0.5 9.9 2.7 2.1 1 1 0 2 2 2 0 Bacteriophage abortive infection AbiH FGF-BP1 PF06473.7 EME29011.1 - 0.38 10.3 5.5 0.3 10.6 2.7 1.6 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) WD40 PF00400.27 EME29012.1 - 1e-14 53.7 13.9 0.0011 18.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EME29012.1 - 0.0016 18.1 0.0 0.071 12.8 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Bromodomain PF00439.20 EME29013.1 - 9.9e-21 73.4 0.1 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EME29013.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME29013.1 - 2.2e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME29013.1 - 0.00016 21.8 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME29013.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Peptidase_M20 PF01546.23 EME29014.1 - 2.3e-27 95.7 0.0 3.1e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EME29014.1 - 9.2e-10 38.5 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 EME29014.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain 14-3-3 PF00244.15 EME29015.1 - 9.7e-114 378.3 5.4 1.2e-113 378.0 3.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1900 PF08954.6 EME29015.1 - 0.018 14.5 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) DUF3106 PF11304.3 EME29015.1 - 0.023 15.0 3.8 0.12 12.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF885 PF05960.6 EME29015.1 - 0.096 11.8 3.2 0.058 12.5 1.1 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) CCDC-167 PF15188.1 EME29015.1 - 0.27 11.2 4.2 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 HMG_box_5 PF14887.1 EME29015.1 - 0.57 10.0 7.3 0.14 11.9 0.6 2.7 3 0 0 3 3 3 0 HMG (high mobility group) box 5 SHP PF03579.8 EME29018.1 - 0.041 13.2 0.2 0.069 12.5 0.2 1.4 1 0 0 1 1 1 0 Small hydrophobic protein CDC73 PF05179.9 EME29019.1 - 7.8e-54 182.8 1.0 1e-53 182.4 0.4 1.3 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DNA_pol_delta_4 PF04081.8 EME29020.1 - 1.6e-18 67.1 0.4 3.1e-18 66.2 0.3 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Pinin_SDK_N PF04697.8 EME29020.1 - 0.083 12.9 0.3 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region RabGAP-TBC PF00566.13 EME29021.1 - 5.7e-54 182.8 1.0 1.1e-53 181.8 0.7 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M24 PF00557.19 EME29022.1 - 5.6e-45 153.4 0.0 7.6e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EME29022.1 - 7.1e-23 81.5 0.0 4.2e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pro_isomerase PF00160.16 EME29022.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M24 PF00557.19 EME29023.1 - 6.9e-45 153.1 0.0 9.7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pro_isomerase PF00160.16 EME29023.1 - 2.6e-25 89.4 0.0 4.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Creatinase_N PF01321.13 EME29023.1 - 1e-22 81.0 0.0 5.1e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mito_carr PF00153.22 EME29024.1 - 1.3e-55 185.0 6.7 1.6e-21 75.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CCCH PF00642.19 EME29025.1 - 2.7e-07 30.1 1.5 4.3e-07 29.4 1.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec16_C PF12931.2 EME29026.1 - 5.7e-10 39.3 0.0 6.2e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 LSM14 PF12701.2 EME29027.1 - 2e-34 117.2 0.0 4.8e-34 116.0 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EME29027.1 - 0.00015 21.5 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain ECR1_N PF14382.1 EME29028.1 - 2.5e-06 26.6 0.1 4.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region AMP-binding PF00501.23 EME29029.1 - 1.2e-84 284.1 0.0 1.5e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme His_Phos_2 PF00328.17 EME29030.1 - 3.8e-37 128.4 0.0 5.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Adaptin_N PF01602.15 EME29031.1 - 1.3e-97 327.2 2.3 1.8e-97 326.9 1.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EME29031.1 - 5.6e-40 136.6 0.1 1.3e-39 135.4 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EME29031.1 - 5.4e-14 52.2 1.6 6.2e-05 23.1 0.0 5.2 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EME29031.1 - 2.9e-08 33.1 7.4 1.4 9.2 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 EME29031.1 - 3e-07 30.4 6.2 0.00082 19.2 0.1 4.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Alpha_adaptin_C PF02296.11 EME29031.1 - 0.0015 18.5 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain DUF2435 PF10363.4 EME29031.1 - 0.0034 17.2 0.2 0.51 10.2 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) UNC45-central PF11701.3 EME29031.1 - 0.0066 16.1 0.3 1.3 8.6 0.0 3.2 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EME29031.1 - 0.0081 15.5 1.9 2.3 7.5 0.1 3.3 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EME29031.1 - 0.01 16.3 6.2 0.61 10.6 0.1 5.5 6 1 1 7 7 6 0 HEAT-like repeat Coatomer_b_Cpla PF14806.1 EME29031.1 - 0.017 14.7 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform AP4E_app_platf PF14807.1 EME29031.1 - 0.065 13.4 0.1 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EME29031.1 - 0.19 11.6 2.2 38 4.2 0.0 4.9 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat CPSase_L_D2 PF02786.12 EME29032.1 - 3.4e-78 261.7 1.3 4.6e-78 261.3 0.2 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME29032.1 - 3.4e-42 143.0 0.1 6.6e-42 142.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME29032.1 - 3.5e-30 104.1 0.0 1.8e-29 101.8 0.0 2.3 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EME29032.1 - 4.1e-16 58.3 0.3 1.2e-15 56.9 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EME29032.1 - 7.5e-13 48.6 0.0 2.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME29032.1 - 8.1e-12 44.5 0.0 2.1e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME29032.1 - 1.7e-09 37.2 0.1 1.5e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME29032.1 - 1e-07 31.5 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.1 EME29032.1 - 1.8e-05 24.9 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EME29032.1 - 7.2e-05 22.3 0.1 0.0033 17.0 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 EME29032.1 - 0.00016 21.1 0.5 0.0021 17.5 0.0 3.0 3 1 0 3 3 3 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EME29032.1 - 0.0076 15.8 0.5 0.016 14.8 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_2 PF12700.2 EME29032.1 - 0.0089 15.2 0.1 0.019 14.1 0.1 1.5 1 1 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.1 EME29032.1 - 0.016 14.8 0.3 0.061 13.0 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.9 EME29032.1 - 0.028 14.3 0.1 0.061 13.1 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp domain Complex1_49kDa PF00346.14 EME29033.1 - 0.043 12.8 5.0 2.1 7.3 0.3 2.7 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pollen_allerg_2 PF01620.11 EME29033.1 - 0.14 12.5 0.3 0.7 10.2 0.1 2.2 1 1 0 1 1 1 0 Ribonuclease (pollen allergen) DUF3037 PF11236.3 EME29033.1 - 7.4 6.6 11.8 0.51 10.4 1.3 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF3037) Mis12 PF05859.7 EME29034.1 - 1.2e-08 34.9 1.2 1.6e-08 34.4 0.2 1.7 2 0 0 2 2 2 1 Mis12 protein DUF1539 PF07560.6 EME29034.1 - 0.015 15.1 0.7 0.028 14.2 0.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) START PF01852.14 EME29035.1 - 3.1e-18 65.8 0.0 4.9e-18 65.1 0.0 1.3 1 1 0 1 1 1 1 START domain START PF01852.14 EME29036.1 - 9.3e-21 74.1 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 START domain DCP2 PF05026.8 EME29037.1 - 5.8e-29 99.8 2.7 1.2e-28 98.8 1.8 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EME29037.1 - 5e-17 61.8 0.0 9.7e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF972 PF06156.8 EME29038.1 - 0.0093 16.3 7.7 0.0093 16.3 5.4 6.0 2 1 3 6 6 6 3 Protein of unknown function (DUF972) Cpn10 PF00166.16 EME29039.1 - 1e-26 92.6 0.0 1.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Sec1 PF00995.18 EME29040.1 - 3e-93 313.4 3.2 4.2e-93 312.9 2.2 1.2 1 0 0 1 1 1 1 Sec1 family Peptidase_M13_N PF05649.8 EME29041.1 - 1.3e-83 281.2 0.0 1.7e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EME29041.1 - 1e-65 220.7 0.0 1.9e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 WhiA_N PF10298.4 EME29041.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain HR1 PF02185.11 EME29041.1 - 0.06 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Hr1 repeat DUF896 PF05979.7 EME29041.1 - 0.14 11.7 0.5 0.32 10.6 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) PGPGW PF09656.5 EME29041.1 - 0.85 8.9 2.7 1.7 8.0 1.9 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Glyco_tran_28_C PF04101.11 EME29042.1 - 3.3e-27 95.1 0.2 3.9e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EME29042.1 - 2.2e-06 27.0 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 DUF4271 PF14093.1 EME29044.1 - 0.52 9.9 8.8 0.33 10.5 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Arch_ATPase PF01637.13 EME29045.1 - 0.0032 17.2 0.1 0.03 14.0 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AA_permease_2 PF13520.1 EME29049.1 - 2.1e-32 112.2 67.0 2.7e-32 111.8 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME29049.1 - 9e-27 93.5 62.0 2.9e-26 91.8 43.0 1.6 1 1 0 1 1 1 1 Amino acid permease DUF4027 PF13219.1 EME29049.1 - 0.037 13.4 0.9 11 5.5 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) DUF4044 PF13253.1 EME29049.1 - 1.1 8.4 6.0 0.42 9.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) DUF2613 PF11021.3 EME29049.1 - 1.8 8.3 5.0 9.7 5.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Rieske PF00355.21 EME29050.1 - 9.3e-17 60.3 0.2 1.4e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.5 EME29050.1 - 8.5e-16 57.6 1.1 8.5e-16 57.6 0.8 1.9 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit La PF05383.12 EME29051.1 - 3.2e-15 55.6 0.8 8.2e-15 54.3 0.6 1.8 1 0 0 1 1 1 1 La domain Pur_DNA_glyco PF02245.11 EME29052.1 - 0.059 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Ribosomal_L2_C PF03947.13 EME29053.1 - 9.8e-43 145.0 1.5 1.6e-42 144.3 1.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EME29053.1 - 7.9e-15 54.5 0.1 1.8e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 EME29053.1 - 0.011 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) TPR_11 PF13414.1 EME29054.1 - 4.1e-83 273.0 36.8 4.1e-22 77.5 0.0 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EME29054.1 - 4.4e-70 228.6 39.9 4.2e-09 35.6 1.5 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EME29054.1 - 4.7e-57 185.3 36.8 1.7e-07 30.6 0.7 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 EME29054.1 - 5.5e-34 113.3 32.1 2.8e-05 23.5 1.3 9.8 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EME29054.1 - 1.9e-31 107.7 22.7 3.7e-09 36.4 1.2 6.3 4 2 1 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EME29054.1 - 2.7e-28 95.8 9.8 0.0015 18.9 0.4 9.2 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME29054.1 - 5e-28 97.1 14.4 4.7e-07 30.3 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EME29054.1 - 8.8e-28 94.1 19.6 0.00019 21.3 0.1 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME29054.1 - 2.6e-20 72.5 18.5 0.00012 22.3 0.0 6.8 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EME29054.1 - 6.9e-20 69.2 19.7 4.5e-07 29.1 0.2 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME29054.1 - 4.9e-19 67.9 9.7 5e-05 23.0 0.0 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EME29054.1 - 1.9e-10 40.7 23.0 0.00078 19.5 3.2 5.2 2 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EME29054.1 - 8.5e-10 38.3 18.4 0.13 12.1 0.1 7.7 6 2 2 8 8 8 4 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EME29054.1 - 4.6e-09 36.1 30.8 0.045 14.2 0.7 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.1 EME29054.1 - 4e-06 26.8 7.0 0.00047 20.2 0.0 5.2 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME29054.1 - 0.00011 21.9 19.5 1.8 8.6 0.6 7.4 9 0 0 9 9 7 2 Tetratricopeptide repeat DUF3856 PF12968.2 EME29054.1 - 0.00025 20.9 9.7 0.082 12.7 1.0 5.1 2 2 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 EME29054.1 - 0.00085 19.5 0.0 23 5.7 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 EME29054.1 - 0.0013 18.5 30.9 2.3 8.1 0.5 7.1 6 1 1 7 7 7 2 MIT (microtubule interacting and transport) domain PPR PF01535.15 EME29054.1 - 0.0075 16.1 7.7 0.74 9.9 0.0 6.0 6 0 0 6 6 6 1 PPR repeat BTAD PF03704.12 EME29054.1 - 0.015 15.6 9.0 8 6.7 2.5 4.8 2 2 2 4 4 4 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.4 EME29054.1 - 0.019 14.2 6.3 4.9 6.4 0.0 5.3 6 0 0 6 6 6 0 SHNi-TPR LMBR1 PF04791.11 EME29054.1 - 0.074 11.6 7.2 1.7 7.0 5.4 2.2 1 1 0 1 1 1 0 LMBR1-like membrane protein TPR_3 PF07720.7 EME29054.1 - 0.16 11.8 28.3 0.29 10.9 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Ndc1_Nup PF09531.5 EME29054.1 - 6.2 5.1 11.6 12 4.2 4.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup NifU_N PF01592.11 EME29055.1 - 6.2e-53 178.0 0.1 7.7e-53 177.7 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Jag_N PF14804.1 EME29055.1 - 0.056 13.4 0.9 2.2 8.3 0.3 2.4 2 0 0 2 2 2 0 Jag N-terminus PGK PF00162.14 EME29056.1 - 9.7e-151 501.6 0.0 2.1e-150 500.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoglycerate kinase QRPTase_C PF01729.14 EME29056.1 - 3.3e-52 176.4 0.0 5.9e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EME29056.1 - 2.3e-16 59.3 0.0 7.2e-16 57.7 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain NTP_transf_2 PF01909.18 EME29056.1 - 0.056 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PPR PF01535.15 EME29058.1 - 0.1 12.6 0.3 40 4.4 0.0 3.6 3 0 0 3 3 3 0 PPR repeat BCAS2 PF05700.6 EME29059.1 - 0.083 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) MFS_1 PF07690.11 EME29060.1 - 6.5e-15 54.6 26.9 6.5e-15 54.6 18.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 EME29060.1 - 3.4e-10 39.2 1.4 5.8e-10 38.4 0.9 1.3 1 0 0 1 1 1 1 PUCC protein MFS_2 PF13347.1 EME29060.1 - 7.1e-10 37.8 14.9 3.4e-09 35.6 10.5 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein PHO4 PF01384.15 EME29060.1 - 1.2 7.7 9.0 0.024 13.2 0.7 2.2 3 1 0 3 3 3 0 Phosphate transporter family Sedlin_N PF04628.8 EME29061.1 - 4.5e-26 91.2 0.0 5.5e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sedlin_N PF04628.8 EME29062.1 - 6.2e-36 123.1 0.0 6.9e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EME29062.1 - 4.2e-07 29.7 0.0 4.4e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family DUF1497 PF07384.6 EME29062.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) LsmAD PF06741.8 EME29063.1 - 8.3e-24 83.4 2.3 1.5e-23 82.6 0.7 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EME29063.1 - 7.6e-14 51.3 0.0 1.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.10 EME29063.1 - 0.017 14.5 0.1 0.19 11.2 0.0 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region LSM PF01423.17 EME29063.1 - 0.046 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 LSM domain Colicin-DNase PF12639.2 EME29063.1 - 0.44 10.8 5.6 1.2 9.3 1.1 2.5 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin RR_TM4-6 PF06459.7 EME29065.1 - 0.098 12.5 3.3 0.11 12.3 2.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAP PF15228.1 EME29065.1 - 0.53 11.0 5.8 0.3 11.8 0.9 2.1 2 0 0 2 2 2 0 Death-associated protein SYS1 PF09801.4 EME29066.1 - 1.3e-32 112.8 11.5 1.6e-32 112.4 8.0 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Clavanin PF05452.6 EME29066.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Clavanin SYS1 PF09801.4 EME29067.1 - 1.3e-32 112.8 11.5 1.6e-32 112.4 8.0 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Clavanin PF05452.6 EME29067.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Clavanin Y_phosphatase2 PF03162.8 EME29068.1 - 2.5e-26 92.0 0.0 2.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family MscS_TM PF12794.2 EME29069.1 - 0.22 10.0 8.2 4 5.9 5.7 2.2 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MNHE PF01899.11 EME29069.1 - 0.26 10.9 6.5 0.11 12.0 1.6 2.1 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit CLP_protease PF00574.18 EME29070.1 - 3.1e-63 212.7 0.0 3.9e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease DHquinase_II PF01220.14 EME29070.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Dehydroquinase class II DUF221 PF02714.10 EME29071.1 - 3.4e-75 252.9 34.9 3.4e-75 252.9 24.2 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME29071.1 - 1.4e-32 112.4 5.6 1.4e-32 112.4 3.9 4.0 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport tRNA-synt_2 PF00152.15 EME29072.1 - 8.4e-91 304.2 0.4 1.1e-90 303.8 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME29072.1 - 3.5e-15 55.6 0.6 6.4e-15 54.7 0.4 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME29072.1 - 6.3e-07 28.8 0.2 0.0077 15.4 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EME29072.1 - 0.094 12.2 0.4 8 6.0 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) ADK PF00406.17 EME29073.1 - 1.6e-39 135.1 0.0 2.1e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EME29073.1 - 3.3e-09 36.7 0.0 5.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME29073.1 - 5e-09 36.5 0.0 8.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME29073.1 - 1.4e-06 29.1 0.0 2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME29073.1 - 0.029 14.1 0.1 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EME29073.1 - 0.063 12.3 0.3 0.45 9.5 0.2 2.0 1 1 0 1 1 1 0 Zeta toxin PAS_7 PF12860.2 EME29073.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 PAS fold Thioredoxin PF00085.15 EME29074.1 - 3.1e-57 190.6 0.0 1.5e-29 101.6 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EME29074.1 - 1.1e-14 54.6 0.2 9.7e-07 28.9 0.2 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME29074.1 - 4.1e-14 52.4 0.1 9e-06 25.7 0.0 3.7 2 2 1 3 3 3 2 Thioredoxin-like ERp29 PF07749.7 EME29074.1 - 4.7e-13 49.5 3.1 4.9e-13 49.5 1.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 EME29074.1 - 4e-12 45.9 0.0 2.5e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EME29074.1 - 1.4e-08 34.7 0.1 0.0066 16.2 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EME29074.1 - 2.7e-08 33.5 0.0 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EME29074.1 - 4.9e-06 26.1 0.1 0.066 12.7 0.1 2.4 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EME29074.1 - 7.4e-06 25.5 0.2 0.083 12.4 0.0 2.6 1 1 0 2 2 2 2 Thioredoxin DUF836 PF05768.9 EME29074.1 - 0.00012 22.2 0.0 1 9.6 0.0 2.8 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EME29074.1 - 0.00082 19.4 0.2 0.4 10.6 0.1 2.8 1 1 1 2 2 2 1 Thioredoxin Glutaredoxin PF00462.19 EME29074.1 - 0.0016 18.3 0.5 2.5 8.1 0.0 3.5 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin_3 PF13192.1 EME29074.1 - 0.0078 16.0 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 EME29074.1 - 0.015 14.7 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 EME29074.1 - 0.032 13.7 0.1 14 5.2 0.0 3.0 2 1 1 3 3 3 0 Thioredoxin DSBA PF01323.15 EME29074.1 - 0.052 13.0 0.1 1.2 8.6 0.0 2.9 2 1 1 3 3 3 0 DSBA-like thioredoxin domain MT-A70 PF05063.9 EME29075.1 - 1.6e-37 128.7 0.0 2e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Pex2_Pex12 PF04757.9 EME29076.1 - 2.5e-33 115.4 4.2 6.2e-33 114.1 2.9 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EME29076.1 - 0.022 14.7 11.6 0.078 13.0 8.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME29076.1 - 0.026 14.1 14.2 0.054 13.1 9.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME29076.1 - 0.72 9.7 13.0 2.2 8.1 9.0 1.9 1 1 0 1 1 1 0 Ring finger domain VWC PF00093.13 EME29076.1 - 0.9 9.6 8.8 1.7 8.8 6.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain zf-RING_UBOX PF13445.1 EME29076.1 - 1.7 8.3 8.7 3.7 7.3 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EME29076.1 - 7.9 6.2 13.4 28 4.5 9.4 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Pex2_Pex12 PF04757.9 EME29077.1 - 2.2e-33 115.5 4.2 5.6e-33 114.2 2.9 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EME29077.1 - 0.024 14.6 11.6 0.076 13.0 8.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME29077.1 - 0.029 14.0 14.2 0.052 13.2 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2102 PF09875.4 EME29077.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) VWC PF00093.13 EME29077.1 - 0.89 9.7 8.8 1.6 8.8 6.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type C domain zf-RING_2 PF13639.1 EME29077.1 - 0.91 9.4 13.3 2.7 7.8 9.2 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 EME29077.1 - 1.8 8.3 8.7 3.6 7.3 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EME29077.1 - 7.3 6.4 13.3 24 4.7 9.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain DUF1796 PF08795.5 EME29079.1 - 0.021 14.4 0.6 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DUF4646 PF15496.1 EME29079.1 - 0.042 13.8 0.4 0.06 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) BCDHK_Adom3 PF10436.4 EME29079.1 - 0.054 13.0 0.9 0.14 11.7 0.7 1.7 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase F-box-like PF12937.2 EME29080.1 - 1.5e-10 40.5 3.0 5.1e-10 38.9 2.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME29080.1 - 3.3e-09 36.1 0.9 3.3e-09 36.1 0.6 2.2 2 0 0 2 2 2 1 F-box domain LSM PF01423.17 EME29081.1 - 5.7e-18 64.2 0.1 6.6e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME29081.1 - 0.084 12.8 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF577 PF04510.7 EME29081.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF577) ELO PF01151.13 EME29082.1 - 1.1e-52 178.8 23.1 1.5e-52 178.3 16.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DnaJ PF00226.26 EME29084.1 - 2.1e-23 81.8 1.1 2.1e-23 81.8 0.8 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4460 PF14687.1 EME29084.1 - 0.013 15.2 1.8 0.039 13.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) RIIa PF02197.12 EME29084.1 - 0.031 13.6 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit WD40 PF00400.27 EME29085.1 - 1.2e-37 126.4 19.1 3.1e-08 33.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME29085.1 - 2.9e-10 40.1 0.0 0.032 13.9 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EME29085.1 - 0.0068 16.1 4.3 1 9.0 0.1 3.9 3 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term zf-CCCH PF00642.19 EME29086.1 - 4.5e-09 35.7 2.2 4.5e-09 35.7 1.6 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EME29086.1 - 1.3e-08 34.7 8.8 1.3e-08 34.7 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME29086.1 - 7.8e-08 31.8 5.5 7.8e-08 31.8 3.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME29086.1 - 1.7e-06 27.7 7.7 1.7e-06 27.7 5.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME29086.1 - 4.8e-06 26.1 8.9 4.8e-06 26.1 6.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME29086.1 - 1.5e-05 24.5 6.6 1.5e-05 24.5 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME29086.1 - 0.00022 20.8 1.9 0.00022 20.8 1.3 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME29086.1 - 0.00038 20.2 7.5 0.00038 20.2 5.2 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EME29086.1 - 0.2 11.1 2.6 0.44 10.0 1.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4580 PF15162.1 EME29087.1 - 0.071 12.4 0.3 0.073 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) DUF4580 PF15162.1 EME29088.1 - 0.11 11.7 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) MutL_C PF08676.6 EME29089.1 - 0.05 13.2 0.5 0.09 12.3 0.3 1.3 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Proteasom_Rpn13 PF04683.8 EME29091.1 - 5.7e-17 61.5 0.1 1.1e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF563 PF04577.9 EME29092.1 - 3.9e-16 59.5 0.2 5.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF563) FmdA_AmdA PF03069.10 EME29093.1 - 8.5e-128 426.1 0.0 1e-127 425.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DNMT1-RFD PF12047.3 EME29094.1 - 1.9e-09 37.3 0.0 5.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain ABC2_membrane PF01061.19 EME29095.1 - 1.7e-34 118.8 35.3 2.7e-34 118.1 24.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME29095.1 - 7.6e-25 87.8 0.0 1.9e-24 86.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EME29095.1 - 1.6e-09 38.1 2.1 7.5e-05 22.8 0.0 3.0 3 1 1 4 4 2 2 AAA domain AAA_25 PF13481.1 EME29095.1 - 1.1e-06 28.2 0.0 0.00046 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EME29095.1 - 1.5e-05 24.3 0.1 0.17 11.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME29095.1 - 2.4e-05 23.7 0.1 5.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EME29095.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 EME29095.1 - 8.5e-05 21.7 29.0 0.00015 20.8 20.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_17 PF13207.1 EME29095.1 - 0.00012 22.8 0.0 0.00026 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME29095.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME29095.1 - 0.0026 17.8 0.0 0.014 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME29095.1 - 0.0029 17.1 0.0 0.032 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EME29095.1 - 0.0029 17.9 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME29095.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_35 PF14516.1 EME29095.1 - 0.0076 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EME29095.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EME29095.1 - 0.012 15.3 0.0 0.23 11.1 0.0 2.5 2 1 0 3 3 3 0 NTPase NACHT PF05729.7 EME29095.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EME29095.1 - 0.016 14.9 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EME29095.1 - 0.016 15.0 0.1 0.06 13.2 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_PrkA PF08298.6 EME29095.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.17 EME29095.1 - 0.05 13.7 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EME29095.1 - 0.063 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME29095.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EME29095.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 1 0 Adenylylsulphate kinase T2SE PF00437.15 EME29095.1 - 0.14 11.0 1.9 0.58 9.0 0.0 2.7 4 0 0 4 4 4 0 Type II/IV secretion system protein Rad17 PF03215.10 EME29095.1 - 0.15 10.7 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EME29095.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME29095.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 EME29096.1 - 1.4e-06 27.8 7.2 2.4e-06 27.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EME29098.1 - 1.6e-37 128.0 0.0 2.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME29098.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic E2 family B Mu-transpos_C PF09299.6 EME29098.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Mu transposase, C-terminal DUF4402 PF14352.1 EME29099.1 - 0.0055 17.1 0.1 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4402) Peptidase_M50 PF02163.17 EME29100.1 - 5.9e-15 54.7 2.9 1.8e-12 46.6 1.8 2.7 2 1 0 2 2 2 1 Peptidase family M50 DUF3540 PF12059.3 EME29100.1 - 0.48 10.0 6.7 0.37 10.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) Apc1 PF12859.2 EME29100.1 - 1.3 9.2 4.1 9.4 6.5 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 Meth_synt_2 PF01717.13 EME29101.1 - 9.4e-151 501.3 0.0 3.6e-143 476.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME29101.1 - 1.7e-105 352.7 0.0 1.7e-91 306.7 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 EME29101.1 - 0.031 13.7 0.1 0.078 12.4 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain Spo0M PF07070.6 EME29101.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein AMP-binding PF00501.23 EME29102.1 - 2e-85 286.6 0.0 2.4e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME29102.1 - 3.4e-15 56.7 0.1 1.5e-14 54.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SPC12 PF06645.8 EME29103.1 - 2.1e-07 30.6 0.3 2.9e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ATP_synt_I PF03899.10 EME29103.1 - 0.09 12.9 0.4 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 ATP synthase I chain DUF2733 PF10813.3 EME29103.1 - 0.16 11.5 0.2 0.7 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) DUF866 PF05907.8 EME29104.1 - 6.6e-22 77.7 0.8 8e-22 77.4 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.8 EME29104.1 - 0.071 12.8 6.1 0.39 10.4 2.6 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.9 EME29104.1 - 0.2 11.6 3.4 0.11 12.5 0.5 1.9 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF866 PF05907.8 EME29105.1 - 1.4e-28 99.3 3.1 1.6e-28 99.2 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.8 EME29105.1 - 0.08 12.6 5.8 0.47 10.1 2.7 2.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.9 EME29105.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PUF PF00806.14 EME29106.1 - 4.4e-51 167.5 16.5 1.1e-07 30.8 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Utp21 PF04192.7 EME29107.1 - 4.1e-24 84.9 0.9 6.9e-24 84.2 0.6 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EME29107.1 - 1.7e-19 68.8 6.6 2.8e-07 30.1 0.0 8.5 10 0 0 10 10 10 3 WD domain, G-beta repeat DUF544 PF04424.8 EME29107.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF544) Aldo_ket_red PF00248.16 EME29108.1 - 2.8e-57 193.7 0.0 3.3e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF155 PF02582.9 EME29109.1 - 2.4e-46 157.8 0.0 3.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 YceG PF02618.11 EME29110.1 - 0.018 14.0 0.1 0.021 13.8 0.1 1.1 1 0 0 1 1 1 0 YceG-like family HR1 PF02185.11 EME29111.1 - 0.029 14.1 0.2 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Hr1 repeat ATP-synt_E PF05680.7 EME29111.1 - 0.059 13.3 2.7 0.15 12.0 1.9 1.6 1 1 0 1 1 1 0 ATP synthase E chain Sec2p PF06428.6 EME29111.1 - 0.094 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p IL3 PF02059.10 EME29111.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin-3 Rhomboid PF01694.17 EME29112.1 - 7.6e-13 48.7 10.8 7.6e-13 48.7 7.5 1.9 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EME29112.1 - 0.16 12.3 12.7 0.046 14.0 5.8 2.0 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) MnhB PF04039.8 EME29112.1 - 1.2 9.1 9.2 0.17 11.9 2.2 2.3 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF2754 PF10953.3 EME29112.1 - 1.9 8.5 10.1 2.6 8.1 1.0 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2754) Rhomboid PF01694.17 EME29113.1 - 2.2e-15 56.9 12.2 2.2e-15 56.9 8.5 1.9 2 0 0 2 2 2 1 Rhomboid family MnhB PF04039.8 EME29113.1 - 0.12 12.4 5.9 0.17 11.9 2.2 2.2 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF1751 PF08551.5 EME29113.1 - 0.14 12.4 12.7 0.046 14.0 5.8 2.1 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 EME29113.1 - 1.6 8.1 14.8 2.4 7.5 10.3 1.3 1 1 0 1 1 1 0 Der1-like family ApbA_C PF08546.6 EME29114.1 - 8.7e-27 93.5 0.0 1.9e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME29114.1 - 2.2e-26 92.1 0.1 4.7e-26 91.0 0.1 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EME29114.1 - 0.00033 20.5 0.1 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_Gly3P_dh_N PF01210.18 EME29114.1 - 0.0028 17.4 0.1 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EME29114.1 - 0.0064 16.8 0.2 0.019 15.4 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EME29114.1 - 0.075 13.4 0.2 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME29114.1 - 0.08 12.9 0.3 0.22 11.5 0.2 1.8 1 1 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EME29114.1 - 0.086 12.2 0.5 0.16 11.2 0.4 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EME29114.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ubiquitin PF00240.18 EME29115.1 - 6.8e-11 41.4 0.0 2.1e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family FKBP_C PF00254.23 EME29115.1 - 1.5e-08 34.5 0.0 4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Rad60-SLD PF11976.3 EME29115.1 - 6.4e-07 28.9 0.1 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FKBP_N PF01346.13 EME29115.1 - 6.4e-05 22.9 2.2 7.4e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ubiquitin_2 PF14560.1 EME29115.1 - 0.022 14.9 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain HrpE PF06188.7 EME29115.1 - 0.16 11.6 0.4 22 4.7 0.1 2.9 3 0 0 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E Pex19 PF04614.7 EME29115.1 - 0.52 9.8 5.1 1.2 8.7 1.0 2.3 2 0 0 2 2 2 0 Pex19 protein family Ribophorin_II PF05817.9 EME29116.1 - 1e-23 83.4 2.1 1.2e-23 83.2 1.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II VOMI PF03762.12 EME29117.1 - 0.0009 19.2 2.0 0.011 15.6 0.4 3.4 1 1 1 2 2 2 2 Vitelline membrane outer layer protein I (VOMI) PPR_3 PF13812.1 EME29118.1 - 0.00024 21.1 0.0 2.7 8.4 0.0 5.0 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EME29118.1 - 0.00064 19.5 0.7 2.1 8.5 0.0 5.0 4 0 0 4 4 4 1 PPR repeat Vps51 PF08700.6 EME29118.1 - 0.0011 18.7 4.5 0.007 16.1 3.1 2.5 1 0 0 1 1 1 1 Vps51/Vps67 PPR_2 PF13041.1 EME29118.1 - 0.0025 17.7 0.1 2.1 8.3 0.0 4.2 2 1 1 4 4 4 1 PPR repeat family DnaJ PF00226.26 EME29119.1 - 6.3e-21 73.8 1.6 4.8e-19 67.8 0.2 2.4 2 0 0 2 2 2 2 DnaJ domain Ubiq_cyt_C_chap PF03981.7 EME29119.1 - 0.099 12.4 0.8 0.17 11.7 0.1 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C chaperone SGS PF05002.10 EME29119.1 - 6.2 6.6 7.2 73 3.2 5.0 2.5 1 1 0 1 1 1 0 SGS domain Epimerase PF01370.16 EME29120.1 - 8.3e-23 81.0 0.0 2.5e-22 79.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.9 EME29120.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LETM1 PF07766.8 EME29120.1 - 0.14 11.2 0.4 4.2 6.3 0.1 2.4 2 1 0 2 2 2 0 LETM1-like protein Glycos_transf_1 PF00534.15 EME29121.1 - 7.5e-29 100.3 0.0 1.2e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME29121.1 - 6.6e-15 55.4 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME29121.1 - 1.6e-14 54.3 0.0 4e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EME29121.1 - 3.6e-11 43.1 0.0 9e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME29121.1 - 3.1e-09 36.7 0.0 4.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 EME29121.1 - 2.9e-08 33.6 0.0 6.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like AA_permease_2 PF13520.1 EME29122.1 - 2.3e-31 108.7 45.5 3.2e-31 108.3 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME29122.1 - 2.9e-09 35.8 37.0 1.6e-08 33.3 25.6 2.1 1 1 0 1 1 1 1 Amino acid permease UQ_con PF00179.21 EME29123.1 - 7.2e-49 164.8 0.0 8.2e-49 164.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME29123.1 - 3.4e-07 30.0 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EME29123.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EME29123.1 - 0.043 13.7 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L13e PF01294.13 EME29124.1 - 1.4e-81 272.2 3.9 1.9e-81 271.8 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e RRM_1 PF00076.17 EME29125.1 - 1.3e-52 175.2 0.1 2.7e-15 55.7 0.0 5.4 4 1 1 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29125.1 - 2.1e-42 142.9 0.1 3.1e-13 49.5 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29125.1 - 1.8e-23 82.1 1.8 4.3e-08 32.8 0.1 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EME29125.1 - 0.067 13.1 0.0 0.87 9.6 0.0 2.9 4 0 0 4 4 4 0 RNA binding domain HATPase_c PF02518.21 EME29125.1 - 0.089 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_11 PF08241.7 EME29126.1 - 3.4e-19 69.1 0.0 1.2e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29126.1 - 6.5e-14 51.7 0.2 1.4e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME29126.1 - 1.2e-11 44.8 0.1 2.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29126.1 - 1e-10 41.6 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME29126.1 - 8.9e-09 35.7 0.1 6.3e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EME29126.1 - 4.9e-06 25.1 0.0 8.2e-06 24.4 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EME29126.1 - 1.1e-05 26.0 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EME29126.1 - 0.0002 20.7 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EME29126.1 - 0.00024 20.8 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EME29126.1 - 0.00082 19.3 0.1 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EME29126.1 - 0.0013 18.2 0.0 0.003 16.9 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 EME29126.1 - 0.0025 16.9 0.0 0.025 13.7 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.11 EME29126.1 - 0.0037 16.1 0.0 0.28 10.0 0.0 2.2 1 1 1 2 2 2 1 mRNA capping enzyme TehB PF03848.9 EME29126.1 - 0.0045 16.1 0.0 0.015 14.5 0.0 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EME29126.1 - 0.0065 15.2 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EME29126.1 - 0.029 13.4 0.1 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase MutS_V PF00488.16 EME29128.1 - 2e-93 312.1 0.0 3.6e-93 311.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME29128.1 - 4.9e-45 153.8 2.4 1.1e-44 152.7 1.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EME29128.1 - 5.1e-36 123.1 0.0 1.2e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EME29128.1 - 1.4e-20 73.2 3.6 1.4e-20 73.2 2.5 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EME29128.1 - 7e-16 58.5 0.1 3.2e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 EME29128.1 - 0.027 14.0 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME29128.1 - 0.25 11.6 4.5 1.5 9.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain NUMOD3 PF07460.6 EME29129.1 - 1.5e-07 31.2 9.8 0.00015 21.6 0.4 4.0 4 0 0 4 4 4 2 NUMOD3 motif (2 copies) Phage_integrase PF00589.17 EME29129.1 - 0.088 12.4 2.7 0.16 11.6 1.9 1.5 1 0 0 1 1 1 0 Phage integrase family RNA_binding PF01877.12 EME29129.1 - 0.12 12.3 4.4 0.13 12.2 0.3 2.7 3 0 0 3 3 3 0 RNA binding DUF3683 PF12447.3 EME29129.1 - 0.42 10.4 4.3 0.46 10.3 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Cyclase_polyket PF04673.7 EME29131.1 - 0.049 13.6 0.1 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthesis cyclase MHC_II_beta PF00969.14 EME29132.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Glyco_hydro_2_N PF02837.13 EME29134.1 - 0.028 13.9 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain AAA PF00004.24 EME29136.1 - 3.7e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME29136.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME29136.1 - 0.00079 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EME29136.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EME29136.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EME29136.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EME29136.1 - 0.0034 16.5 0.0 0.007 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EME29136.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME29136.1 - 0.0048 16.7 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME29136.1 - 0.0056 15.8 0.1 0.012 14.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EME29136.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME29136.1 - 0.0098 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 EME29136.1 - 0.011 15.7 3.6 0.15 12.0 2.5 2.1 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EME29136.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EME29136.1 - 0.015 15.2 0.0 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME29136.1 - 0.026 14.8 0.3 0.054 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EME29136.1 - 0.029 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EME29136.1 - 0.04 13.5 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME29136.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EME29136.1 - 0.042 14.6 0.2 0.15 12.8 0.0 2.0 2 1 1 3 3 2 0 AAA domain IstB_IS21 PF01695.12 EME29136.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 EME29137.1 - 4.2e-05 23.7 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME29137.1 - 0.00084 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME29137.1 - 0.00086 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EME29137.1 - 0.0014 18.9 0.0 0.0029 17.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EME29137.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EME29137.1 - 0.0033 16.9 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EME29137.1 - 0.0038 16.3 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EME29137.1 - 0.0047 17.0 0.0 0.0099 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME29137.1 - 0.005 16.7 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME29137.1 - 0.0064 15.6 0.7 0.013 14.7 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EME29137.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EME29137.1 - 0.01 15.8 3.3 0.13 12.2 2.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EME29137.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EME29137.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EME29137.1 - 0.015 15.2 0.1 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME29137.1 - 0.026 14.8 0.2 0.061 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EME29137.1 - 0.032 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EME29137.1 - 0.041 14.7 0.1 0.16 12.7 0.0 2.1 2 1 1 3 3 2 0 AAA domain AAA_30 PF13604.1 EME29137.1 - 0.043 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME29137.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Rgp1 PF08737.5 EME29138.1 - 7.4e-31 107.6 1.6 7.6e-31 107.6 0.2 1.6 2 1 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EME29138.1 - 0.067 13.0 1.7 3 7.6 0.0 3.3 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain LSM PF01423.17 EME29139.1 - 5.8e-18 64.1 0.0 7.2e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain TMP-TENI PF02581.12 EME29142.1 - 6.7e-64 214.3 1.0 8.4e-64 213.9 0.7 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI NMO PF03060.10 EME29142.1 - 7.5e-07 28.6 1.4 1.5e-06 27.6 1.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase NanE PF04131.9 EME29142.1 - 0.00016 20.6 0.2 0.00023 20.1 0.1 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.16 EME29142.1 - 0.0019 17.2 0.4 0.0033 16.4 0.3 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.9 EME29142.1 - 0.0023 17.0 0.9 0.0042 16.1 0.7 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 EME29142.1 - 0.0086 15.0 3.1 0.022 13.7 1.5 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF561) IMPDH PF00478.20 EME29142.1 - 0.012 14.4 1.7 0.015 14.2 1.2 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Aldolase PF01081.14 EME29142.1 - 0.026 13.7 0.1 0.078 12.1 0.0 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase ArsA_ATPase PF02374.10 EME29143.1 - 3.1e-79 266.1 0.0 3.9e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EME29143.1 - 1.2e-12 47.6 0.2 2.2e-12 46.8 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME29143.1 - 7e-06 26.0 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME29143.1 - 9.1e-05 21.6 0.3 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EME29143.1 - 0.00018 21.0 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EME29143.1 - 0.00024 20.6 0.5 0.00074 19.0 0.4 1.8 1 1 0 1 1 1 1 AAA-like domain Fer4_NifH PF00142.13 EME29143.1 - 0.0011 18.1 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EME29143.1 - 0.0049 16.3 0.4 0.011 15.2 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EME29143.1 - 0.011 14.6 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein YhjQ PF06564.7 EME29143.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein ArgK PF03308.11 EME29143.1 - 0.015 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 EME29143.1 - 0.016 14.7 0.1 0.044 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EME29143.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 EME29143.1 - 0.02 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EME29143.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME29143.1 - 0.048 13.9 0.1 0.15 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME29143.1 - 0.061 14.1 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EME29143.1 - 0.074 11.9 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EME29143.1 - 0.087 12.0 0.1 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 LpxK PF02606.9 EME29143.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase ParA PF10609.4 EME29143.1 - 0.22 11.4 2.3 2 8.3 0.1 3.2 3 1 0 3 3 3 0 ParA/MinD ATPase like PRMT5 PF05185.11 EME29144.1 - 6.4e-145 483.4 0.0 7.8e-145 483.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EME29144.1 - 0.0042 17.0 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME29144.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.11 EME29145.1 - 2.1e-139 465.2 0.0 1.2e-138 462.8 0.0 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF1838 PF08894.6 EME29146.1 - 4.1e-69 232.4 0.4 5.9e-69 231.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) Cyt-b5 PF00173.23 EME29146.1 - 1.7e-07 30.9 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aldedh PF00171.17 EME29147.1 - 9.1e-125 416.5 0.1 1e-124 416.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 EME29148.1 - 1.1e-120 403.1 0.1 1.2e-120 402.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family peroxidase PF00141.18 EME29149.1 - 1.6e-51 175.0 0.0 2.4e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase 2-oxoacid_dh PF00198.18 EME29150.1 - 5.1e-67 225.5 0.2 8.6e-67 224.7 0.1 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EME29150.1 - 3.6e-26 90.5 0.2 5.3e-15 54.7 0.1 2.6 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl PF00364.17 EME29150.1 - 3.8e-24 84.1 1.8 5.1e-17 61.2 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EME29150.1 - 0.00019 20.9 0.1 0.00075 19.1 0.0 2.0 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.2 EME29150.1 - 0.046 12.8 0.5 0.17 10.9 0.1 2.1 2 1 0 2 2 2 0 HlyD family secretion protein Herpes_LMP2 PF07415.6 EME29151.1 - 0.27 9.7 1.8 0.54 8.7 1.3 1.4 1 1 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Far-17a_AIG1 PF04750.9 EME29152.1 - 8.6e-18 64.2 12.3 1.1e-17 63.9 8.6 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2238 PF09997.4 EME29152.1 - 0.028 13.8 1.2 0.08 12.3 0.8 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) Serpentine_r_xa PF03383.10 EME29152.1 - 0.043 13.5 4.7 0.97 9.1 0.5 2.2 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa DUF997 PF06196.7 EME29152.1 - 6.6 6.3 10.9 6.4 6.3 5.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF997) DUF3119 PF11317.3 EME29153.1 - 3.6e-22 78.6 1.4 5e-22 78.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) Pyr_redox_2 PF07992.9 EME29154.1 - 8.4e-09 35.5 0.1 0.012 15.5 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME29154.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XG_FTase PF03254.8 EME29155.1 - 2.6e-06 26.1 1.7 5.4e-06 25.1 1.1 1.5 1 1 0 1 1 1 1 Xyloglucan fucosyltransferase DUF3446 PF11928.3 EME29155.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) OKR_DC_1_N PF03709.10 EME29155.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PFK PF00365.15 EME29156.1 - 9.1e-28 97.0 0.0 1.1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase DTW PF03942.10 EME29156.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 DTW domain RHD3 PF05879.7 EME29157.1 - 9.5e-43 146.1 0.3 1.2e-42 145.8 0.2 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EME29157.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1826 PF08856.6 EME29157.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) FeoB_N PF02421.13 EME29157.1 - 0.13 11.5 0.2 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Peptidase_M48 PF01435.13 EME29158.1 - 4.1e-49 167.1 0.0 6e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EME29158.1 - 0.016 14.2 1.8 0.027 13.4 0.7 1.8 1 1 1 2 2 2 0 BlaR1 peptidase M56 GFO_IDH_MocA PF01408.17 EME29159.1 - 1.8e-24 86.5 0.1 3.2e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME29159.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain OCD_Mu_crystall PF02423.10 EME29159.1 - 0.0079 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.11 EME29159.1 - 0.016 15.6 0.1 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UBACT PF02134.16 EME29159.1 - 0.038 13.5 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein DapB_N PF01113.15 EME29159.1 - 0.057 13.3 0.1 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 EME29159.1 - 0.068 12.9 0.7 0.14 11.9 0.5 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EME29159.1 - 0.1 12.6 0.1 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Nse4_C PF08743.5 EME29160.1 - 5.6e-17 61.5 0.2 5.3e-14 52.0 0.0 2.5 1 1 1 2 2 2 2 Nse4 C-terminal CP2 PF04516.10 EME29161.1 - 0.033 13.2 0.4 0.05 12.6 0.3 1.2 1 0 0 1 1 1 0 CP2 transcription factor HTH_32 PF13565.1 EME29161.1 - 0.047 14.4 0.0 0.6 10.9 0.0 2.5 1 1 0 1 1 1 0 Homeodomain-like domain PBS_linker_poly PF00427.16 EME29162.1 - 2.5e-34 117.7 0.0 1.1e-33 115.6 0.0 1.9 2 0 0 2 2 2 1 Phycobilisome Linker polypeptide CpcD PF01383.16 EME29162.1 - 5.2e-11 42.5 3.5 8.1e-11 41.9 0.5 2.7 3 0 0 3 3 3 1 CpcD/allophycocyanin linker domain Nop16 PF09420.5 EME29163.1 - 6e-17 62.2 4.9 4.9e-15 56.0 3.4 2.0 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Enkurin PF13864.1 EME29163.1 - 0.23 11.6 2.5 1.9 8.7 0.7 2.2 1 1 1 2 2 2 0 Calmodulin-binding CTP_transf_3 PF02348.14 EME29163.1 - 0.71 9.4 4.3 2 7.9 0.0 2.1 1 1 1 2 2 2 0 Cytidylyltransferase Nop16 PF09420.5 EME29164.1 - 4e-14 53.0 1.3 3.6e-12 46.7 0.9 2.0 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF4499 PF14934.1 EME29165.1 - 1.5e-16 60.1 4.1 1.8e-16 59.8 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2092 PF09865.4 EME29166.1 - 0.012 14.6 0.1 0.022 13.8 0.0 1.4 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2092) YscW PF09619.5 EME29166.1 - 0.023 14.3 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) GATA PF00320.22 EME29167.1 - 6.7e-17 60.5 2.7 2e-16 59.0 1.9 1.8 1 0 0 1 1 1 1 GATA zinc finger Peptidase_C15 PF01470.12 EME29168.1 - 7.5e-16 58.5 0.0 9.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase SAP30_Sin3_bdg PF13867.1 EME29169.1 - 5.9e-14 51.6 0.1 1.1e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Extensin-like_C PF06904.7 EME29169.1 - 0.091 12.5 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Extensin-like protein C-terminus Tcf25 PF04910.9 EME29170.1 - 1.6e-54 185.2 2.7 1.6e-54 185.2 1.9 1.4 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_16 PF13432.1 EME29170.1 - 0.059 14.0 0.3 0.24 12.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME29170.1 - 0.064 13.9 0.8 0.68 10.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4662 PF15578.1 EME29170.1 - 0.15 11.6 2.9 0.46 10.0 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) P5CR_dimer PF14748.1 EME29171.1 - 6e-36 122.7 0.9 1.2e-35 121.7 0.4 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EME29171.1 - 8.5e-18 64.5 0.1 3.3e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EME29171.1 - 0.0013 17.6 0.0 0.0024 16.8 0.0 1.5 1 1 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EME29171.1 - 0.0044 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME29171.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tox-PL-2 PF15643.1 EME29171.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 Ribonuc_P_40 PF08584.6 EME29172.1 - 4.8e-09 35.6 0.6 6.5e-08 31.9 0.4 2.4 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit IGPS PF00218.16 EME29173.1 - 1.8e-71 240.2 0.1 2.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 EME29173.1 - 0.053 13.0 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EME29173.1 - 0.073 12.0 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase KCNQ_channel PF03520.9 EME29174.1 - 3.9e-05 23.0 1.6 5.8e-05 22.4 1.1 1.2 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel APG6 PF04111.7 EME29174.1 - 0.034 13.2 11.1 0.048 12.7 7.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 EME29174.1 - 0.047 13.7 9.6 0.067 13.2 6.2 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.10 EME29174.1 - 0.066 12.3 3.2 0.075 12.2 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin PF00261.15 EME29174.1 - 0.12 11.4 15.0 0.75 8.8 10.4 1.9 1 1 1 2 2 2 0 Tropomyosin His_Phos_2 PF00328.17 EME29174.1 - 0.15 11.3 4.0 0.12 11.7 1.1 1.7 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) Lebercilin PF15619.1 EME29174.1 - 0.28 10.5 12.4 0.38 10.1 8.6 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4164 PF13747.1 EME29174.1 - 0.3 11.2 4.5 0.55 10.4 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Latarcin PF10279.4 EME29174.1 - 0.46 10.6 7.0 1.1 9.4 3.9 2.3 2 1 0 2 2 2 0 Latarcin precursor HAUS5 PF14817.1 EME29174.1 - 1 7.8 10.7 1.2 7.5 5.2 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Spc24 PF08286.6 EME29174.1 - 1.3 8.7 9.3 0.11 12.2 1.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EME29174.1 - 2.7 7.8 13.5 6.8 6.5 6.8 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PRONE PF03759.8 EME29175.1 - 3.3e-31 108.1 0.4 5.9e-31 107.3 0.3 1.4 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) MIT PF04212.13 EME29175.1 - 3.1e-08 33.3 0.1 9.5e-08 31.8 0.1 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain USP8_dimer PF08969.6 EME29175.1 - 0.00026 20.9 0.2 0.0053 16.6 0.1 2.7 2 0 0 2 2 2 1 USP8 dimerisation domain PRONE PF03759.8 EME29176.1 - 1.8e-20 72.8 1.4 2e-20 72.6 0.9 1.0 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) cwf18 PF08315.7 EME29176.1 - 0.2 12.0 3.9 0.33 11.3 2.7 1.4 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor Pkinase PF00069.20 EME29177.1 - 8.5e-53 179.1 0.0 1.3e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29177.1 - 7.9e-45 152.9 0.0 1.2e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME29177.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Melibiase PF02065.13 EME29178.1 - 3.8e-149 496.6 0.0 5e-149 496.2 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EME29178.1 - 2.1e-05 23.5 0.0 4.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF1752 PF08550.5 EME29178.1 - 0.00015 21.2 2.9 0.00037 19.9 2.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Raffinose_syn PF05691.7 EME29178.1 - 0.02 12.4 0.0 0.038 11.5 0.0 1.3 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_97 PF10566.4 EME29178.1 - 0.16 11.0 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glycoside hydrolase 97 Mlf1IP PF10248.4 EME29179.1 - 1e-09 38.2 0.2 1.3e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein SAM_2 PF07647.12 EME29181.1 - 0.015 15.1 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME29181.1 - 0.027 14.6 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_22 PF13401.1 EME29181.1 - 0.059 13.5 0.1 1 9.4 0.0 3.0 3 1 0 3 3 3 0 AAA domain LRR_6 PF13516.1 EME29182.1 - 9e-39 127.1 37.0 0.0013 18.5 0.1 13.1 12 0 0 12 12 12 11 Leucine Rich repeat LRR_1 PF00560.28 EME29182.1 - 0.0015 18.2 3.4 1.2e+02 3.3 0.0 7.5 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.2 EME29182.1 - 0.0017 17.8 13.4 4.2 7.1 0.0 6.3 4 1 3 7 7 7 2 Leucine Rich repeats (2 copies) SpoU_sub_bind PF08032.7 EME29182.1 - 0.0074 16.4 0.3 41 4.4 0.0 5.2 7 0 0 7 7 7 0 RNA 2'-O ribose methyltransferase substrate binding zf-RING_6 PF14835.1 EME29182.1 - 0.015 15.0 16.1 0.014 15.1 9.0 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein PglZ PF08665.7 EME29182.1 - 0.016 14.9 0.0 0.66 9.6 0.0 3.1 2 1 1 3 3 3 0 PglZ domain Methyltransf_21 PF05050.7 EME29184.1 - 5.1e-15 55.8 0.0 9.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EME29184.1 - 0.00028 21.4 0.0 0.00058 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cyt-b5 PF00173.23 EME29186.1 - 5e-24 83.8 0.0 6.1e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF948 PF06103.6 EME29187.1 - 0.00043 20.0 1.0 0.00043 20.0 0.7 4.3 2 1 2 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF4349 PF14257.1 EME29187.1 - 0.0057 15.9 0.9 0.036 13.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) Amnionless PF14828.1 EME29187.1 - 0.0057 15.1 2.4 0.0057 15.1 1.7 2.1 2 1 0 2 2 2 1 Amnionless Viral_P18 PF04521.8 EME29187.1 - 0.028 13.8 0.1 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Med10 PF09748.4 EME29187.1 - 0.052 13.3 0.6 0.052 13.3 0.4 3.4 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Cob_adeno_trans PF01923.13 EME29187.1 - 0.057 13.2 1.9 1.3 8.7 0.5 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF2408 PF10303.4 EME29187.1 - 0.17 12.0 7.7 2.2 8.3 2.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Phage_GPO PF05929.6 EME29187.1 - 0.26 10.5 4.6 0.096 11.9 1.2 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4618 PF15397.1 EME29187.1 - 0.43 9.8 12.6 0.88 8.8 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) RasGAP_C PF03836.10 EME29187.1 - 0.82 9.3 11.6 2 8.1 1.0 3.3 2 1 0 3 3 3 0 RasGAP C-terminus CENP-F_leu_zip PF10473.4 EME29187.1 - 0.87 9.4 8.9 4.2 7.2 1.3 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 EME29187.1 - 0.9 9.9 6.1 5.9 7.3 0.0 3.2 1 1 0 3 3 3 0 SlyX Fib_alpha PF08702.5 EME29187.1 - 3.6 7.7 19.7 0.31 11.1 5.4 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 EME29187.1 - 3.9 7.5 7.2 7.2 6.7 0.2 3.2 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Lectin_N PF03954.9 EME29187.1 - 5.2 6.4 9.8 15 4.9 2.0 3.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HR1 PF02185.11 EME29187.1 - 6.5 6.5 13.2 2.2 8.0 0.1 3.7 4 1 0 4 4 4 0 Hr1 repeat Prefoldin_2 PF01920.15 EME29187.1 - 7.6 6.3 13.5 1.9 8.3 1.3 3.6 2 1 1 3 3 3 0 Prefoldin subunit Acetyltransf_3 PF13302.1 EME29188.1 - 4.7e-20 72.1 0.0 7.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME29188.1 - 2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME29188.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME29188.1 - 2.9e-06 27.1 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HLH PF00010.21 EME29188.1 - 0.0008 19.0 0.6 0.0014 18.2 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FR47 PF08445.5 EME29188.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acyltransferase PF01553.16 EME29189.1 - 2.7e-14 52.7 0.0 4.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase GPAT_N PF14829.1 EME29189.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal TP_methylase PF00590.15 EME29191.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases PPV_E1_C PF00519.12 EME29191.1 - 0.037 12.6 0.0 0.038 12.5 0.0 1.0 1 0 0 1 1 1 0 Papillomavirus helicase COQ9 PF08511.6 EME29192.1 - 9e-19 66.7 0.5 1.4e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 COQ9 HlyIII PF03006.15 EME29194.1 - 1.1e-51 175.3 10.7 2e-51 174.5 7.4 1.4 1 1 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.6 EME29194.1 - 0.11 12.2 2.2 2.7 7.7 0.1 3.2 3 0 0 3 3 3 0 Ycf66 protein N-terminus RCC1 PF00415.13 EME29195.1 - 1e-12 48.0 1.7 1.8e-07 31.2 0.2 3.3 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME29195.1 - 3.5e-12 45.5 0.3 2.5e-09 36.4 0.2 2.7 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RPE65 PF03055.10 EME29196.1 - 2e-122 409.2 0.0 2.6e-122 408.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GHMP_kinases_N PF00288.21 EME29197.1 - 8.4e-07 28.9 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain RNase_Zc3h12a PF11977.3 EME29198.1 - 6.5e-23 81.2 0.0 9.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain HA PF03457.9 EME29198.1 - 0.0089 16.1 0.1 0.71 10.0 0.0 2.5 2 1 0 2 2 2 2 Helicase associated domain DEAD PF00270.24 EME29199.1 - 9.8e-38 129.2 0.4 1.2e-35 122.4 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EME29199.1 - 3.6e-23 81.2 0.1 7.5e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EME29199.1 - 0.0061 16.5 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DUF2999 PF11212.3 EME29199.1 - 0.052 13.6 0.0 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) YGGT PF02325.12 EME29200.1 - 7.5e-16 57.8 3.6 7.5e-16 57.8 2.5 2.1 2 1 0 2 2 2 1 YGGT family Iso_dh PF00180.15 EME29202.1 - 1.1e-69 235.0 0.0 3.6e-69 233.3 0.0 1.7 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_77 PF02446.12 EME29203.1 - 7.9e-148 493.1 3.8 1e-147 492.7 2.6 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.14 EME29203.1 - 1.2e-14 53.6 0.0 2.9e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 Starch binding domain Mito_carr PF00153.22 EME29204.1 - 3.6e-60 199.6 1.7 4.5e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pab87_oct PF13969.1 EME29204.1 - 0.075 13.1 0.0 4.5 7.4 0.0 2.4 1 1 1 2 2 2 0 Pab87 octamerisation domain WD40 PF00400.27 EME29205.1 - 2.3e-29 100.1 12.2 1.2e-09 37.6 0.5 7.8 7 1 0 7 7 7 4 WD domain, G-beta repeat Nbas_N PF15492.1 EME29205.1 - 0.00011 21.3 1.3 0.61 9.1 0.0 4.1 4 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EME29205.1 - 0.0002 21.1 0.1 0.00096 18.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.7 EME29205.1 - 0.00022 20.7 0.0 0.041 13.2 0.0 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EME29205.1 - 0.0011 17.8 1.3 3 6.4 0.1 3.4 2 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EME29205.1 - 0.0084 15.7 0.0 9.1 6.0 0.0 4.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EME29205.1 - 0.044 11.9 3.0 0.25 9.4 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 BatD PF13584.1 EME29205.1 - 0.16 10.5 0.1 0.22 10.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance WD40 PF00400.27 EME29206.1 - 2.3e-29 100.1 12.2 1.2e-09 37.6 0.5 7.8 7 1 0 7 7 7 4 WD domain, G-beta repeat Nbas_N PF15492.1 EME29206.1 - 0.00011 21.3 1.3 0.61 9.1 0.0 4.1 4 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EME29206.1 - 0.0002 21.1 0.1 0.00096 18.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.7 EME29206.1 - 0.00022 20.7 0.0 0.041 13.2 0.0 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EME29206.1 - 0.0011 17.8 1.3 3 6.4 0.1 3.4 2 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EME29206.1 - 0.0084 15.7 0.0 9.1 6.0 0.0 4.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EME29206.1 - 0.044 11.9 3.0 0.25 9.4 0.0 2.5 2 1 0 2 2 2 0 Nucleoporin Nup120/160 BatD PF13584.1 EME29206.1 - 0.16 10.5 0.1 0.22 10.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance KRTAP PF11759.3 EME29207.1 - 0.45 10.7 28.9 1.8 8.8 20.0 1.8 1 1 0 1 1 1 0 Keratin-associated matrix YqzM PF14141.1 EME29207.1 - 3.7 7.3 9.4 2.1 8.2 0.5 2.4 2 0 0 2 2 2 0 YqzM-like protein UbiA PF01040.13 EME29208.1 - 2.9e-27 95.5 19.0 3.7e-27 95.1 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family CoA_binding_3 PF13727.1 EME29208.1 - 0.62 9.8 4.2 0.21 11.4 0.4 2.0 2 0 0 2 2 2 0 CoA-binding domain TFIIS_C PF01096.13 EME29209.1 - 2e-15 56.1 1.7 2e-15 56.1 1.2 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-RING_3 PF14369.1 EME29209.1 - 8.7e-06 25.6 3.0 0.035 14.0 0.1 3.5 3 0 0 3 3 3 1 zinc-finger RNA_POL_M_15KD PF02150.11 EME29209.1 - 2.1e-05 24.0 6.9 0.00068 19.2 0.8 2.9 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EME29209.1 - 0.00032 20.4 9.0 0.079 12.7 0.3 3.0 2 1 0 2 2 2 2 Double zinc ribbon Baculo_LEF5_C PF11792.3 EME29209.1 - 0.002 17.4 0.4 0.002 17.4 0.3 3.2 3 1 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain Lar_restr_allev PF14354.1 EME29209.1 - 0.0028 17.9 5.9 0.003 17.8 0.3 2.7 2 1 0 2 2 2 1 Restriction alleviation protein Lar TerY-C PF15616.1 EME29209.1 - 0.022 14.6 7.3 0.046 13.6 1.8 2.2 1 1 1 2 2 2 0 TerY-C metal binding domain Leu_zip PF15294.1 EME29209.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Leucine zipper zinc_ribbon_2 PF13240.1 EME29209.1 - 0.025 14.0 14.6 0.71 9.4 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-GRF PF06839.7 EME29209.1 - 0.027 14.3 2.9 0.1 12.5 0.6 2.7 2 0 0 2 2 2 0 GRF zinc finger zf-H2C2_2 PF13465.1 EME29209.1 - 0.035 14.3 0.7 0.035 14.3 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-TFIIB PF13453.1 EME29209.1 - 0.057 12.6 2.7 0.95 8.7 1.1 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger Terminase_GpA PF05876.7 EME29209.1 - 0.083 11.2 1.9 0.078 11.3 0.3 1.6 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) A2L_zn_ribbon PF08792.5 EME29209.1 - 0.16 11.4 8.3 5.1 6.6 1.1 3.8 3 1 1 4 4 4 0 A2L zinc ribbon domain Auto_anti-p27 PF06677.7 EME29209.1 - 0.24 11.2 9.0 5.8 6.7 0.8 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 EME29209.1 - 0.31 11.0 8.5 6.1 6.8 0.0 3.9 3 1 0 4 4 4 0 Zinc ribbon domain CpXC PF14353.1 EME29209.1 - 0.37 10.7 5.7 8.1 6.4 0.1 2.9 2 1 1 3 3 3 0 CpXC protein C1_2 PF03107.11 EME29209.1 - 0.42 10.7 0.3 0.42 10.7 0.2 3.2 4 0 0 4 4 2 0 C1 domain C1_1 PF00130.17 EME29209.1 - 0.66 9.7 7.9 0.41 10.4 1.0 2.9 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 EME29209.1 - 0.67 9.8 12.0 6.9 6.6 2.7 3.2 2 2 0 2 2 2 0 IBR domain zf-ribbon_3 PF13248.1 EME29209.1 - 0.97 8.7 16.8 1.1 8.5 0.1 3.8 3 1 1 4 4 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 EME29209.1 - 0.98 9.5 12.9 2.6 8.1 0.1 4.3 4 1 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-IS66 PF13005.2 EME29209.1 - 1 9.4 6.0 9.3 6.3 0.2 3.4 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Cys_rich_CPCC PF14206.1 EME29209.1 - 1 8.9 7.6 9 5.9 0.2 3.6 3 1 1 4 4 4 0 Cysteine-rich CPCC UPF0547 PF10571.4 EME29209.1 - 1.4 8.6 0.1 1.4 8.6 0.0 3.4 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 HypA PF01155.14 EME29209.1 - 1.6 8.4 7.7 2.7 7.7 1.2 2.5 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family Rpr2 PF04032.11 EME29209.1 - 1.7 8.5 10.5 2.1e+02 1.8 7.3 3.1 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-HC5HC2H_2 PF13832.1 EME29209.1 - 2.1 8.3 7.0 0.59 10.1 0.9 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain Nop10p PF04135.7 EME29209.1 - 2.1 8.1 4.6 0.69 9.6 0.4 2.4 3 1 0 3 3 2 0 Nucleolar RNA-binding protein, Nop10p family TF_Zn_Ribbon PF08271.7 EME29209.1 - 2.7 7.3 13.4 2 7.8 2.6 3.6 2 2 2 4 4 4 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EME29209.1 - 3.9 7.3 13.4 0.13 12.1 1.7 3.1 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.14 EME29209.1 - 3.9 7.0 13.2 0.99 8.9 3.0 3.2 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 EME29209.1 - 3.9 7.1 7.7 0.56 9.9 0.9 3.0 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger NOB1_Zn_bind PF08772.6 EME29209.1 - 6.3 6.7 16.8 0.48 10.2 1.1 4.1 3 2 1 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like OrfB_Zn_ribbon PF07282.6 EME29209.1 - 7.3 6.3 11.0 6.8 6.4 2.1 3.2 2 2 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_5 PF13719.1 EME29209.1 - 8.2 6.1 11.8 1.1 8.8 0.4 2.8 3 0 0 3 3 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EME29209.1 - 9.3 6.0 11.9 1.2 8.8 0.4 2.9 3 0 0 3 3 2 0 zinc-ribbon domain XRN_N PF03159.13 EME29211.1 - 5e-91 304.2 0.0 7.6e-91 303.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RNA_pol_Rpb5_C PF01191.14 EME29212.1 - 1e-36 124.3 0.6 2.4e-36 123.1 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EME29212.1 - 1.7e-24 86.0 0.9 3e-24 85.2 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain FliL PF03748.9 EME29212.1 - 0.058 13.3 0.7 0.35 10.8 0.0 2.4 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL OB_NTP_bind PF07717.11 EME29213.1 - 8.3e-29 99.7 0.0 2.5e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME29213.1 - 1.1e-25 89.5 1.5 2.4e-25 88.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME29213.1 - 4.8e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME29213.1 - 4.9e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME29213.1 - 2.1e-07 31.1 0.0 8.6e-07 29.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EME29213.1 - 0.00056 18.9 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EME29213.1 - 0.0012 18.6 0.1 0.0031 17.2 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain Helicase_RecD PF05127.9 EME29213.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.22 EME29213.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.0 2 1 0 2 2 1 0 ABC transporter AAA_33 PF13671.1 EME29213.1 - 0.93 9.3 4.3 2.8 7.8 0.1 3.4 2 2 1 3 3 3 0 AAA domain AAA_23 PF13476.1 EME29213.1 - 5.8 7.1 0.0 5.8 7.1 0.0 3.5 2 1 0 2 2 1 0 AAA domain DcpS_C PF11969.3 EME29214.1 - 1.3e-22 80.2 0.2 1.6e-22 79.9 0.2 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EME29214.1 - 4.5e-09 36.7 1.5 7.8e-09 35.9 1.1 1.4 1 1 0 1 1 1 1 HIT domain CDH PF02611.10 EME29214.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Methyltransf_15 PF09445.5 EME29215.1 - 8.4e-37 126.2 0.0 1.1e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EME29215.1 - 7.3e-08 32.1 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EME29215.1 - 3.6e-06 27.0 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29215.1 - 0.00032 20.3 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29215.1 - 0.0012 19.3 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME29215.1 - 0.0048 16.5 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EME29215.1 - 0.044 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UCH PF00443.24 EME29216.1 - 3.4e-44 150.9 2.6 8.2e-44 149.7 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME29216.1 - 2.7e-21 76.3 3.3 2.7e-21 76.3 2.3 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EME29216.1 - 7.9e-05 22.9 0.7 0.017 15.5 0.0 3.9 3 1 0 3 3 3 1 DUSP domain ubiquitin PF00240.18 EME29216.1 - 0.00028 20.2 0.0 0.00061 19.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_52 PF03512.8 EME29216.1 - 0.064 11.8 0.1 0.24 9.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 ParG PF09274.5 EME29216.1 - 0.071 13.0 0.2 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 ParG Ubie_methyltran PF01209.13 EME29219.1 - 4e-81 271.5 0.4 5.1e-81 271.2 0.2 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EME29219.1 - 7.1e-17 61.3 0.0 9.6e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME29219.1 - 7.7e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME29219.1 - 8.4e-13 48.5 0.0 9.3e-12 45.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29219.1 - 1.7e-09 37.6 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29219.1 - 2.1e-09 37.9 0.0 4.2e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME29219.1 - 8.6e-08 32.5 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME29219.1 - 4.3e-05 23.5 0.0 9.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EME29219.1 - 0.00098 18.8 0.0 0.014 15.0 0.0 2.4 3 0 0 3 3 3 1 Hypothetical methyltransferase UPF0020 PF01170.13 EME29219.1 - 0.075 12.6 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 2-Hacid_dh_C PF02826.14 EME29220.1 - 2e-52 176.9 0.0 2.8e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME29220.1 - 2.3e-16 59.4 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME29220.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3039 PF11238.3 EME29220.1 - 0.019 14.3 0.7 6.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) DOT1 PF08123.8 EME29220.1 - 0.058 12.6 0.1 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 NAD_binding_7 PF13241.1 EME29220.1 - 0.084 13.1 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Mito_carr PF00153.22 EME29221.1 - 3e-67 222.3 1.1 1.4e-25 88.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S6e PF01092.14 EME29222.1 - 1.5e-53 179.7 0.7 2.6e-53 179.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e DEAD PF00270.24 EME29223.1 - 6.8e-45 152.5 0.0 1.5e-43 148.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME29223.1 - 4.2e-27 93.8 0.0 1.1e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EME29223.1 - 0.004 17.4 1.9 0.004 17.4 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) TPR_12 PF13424.1 EME29224.1 - 8.6e-05 22.4 3.8 0.0028 17.5 0.5 2.8 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME29224.1 - 0.00037 20.2 2.0 0.2 11.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EME29224.1 - 0.0039 17.1 14.2 0.014 15.4 9.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 EME29224.1 - 0.012 15.3 0.4 0.17 11.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME29224.1 - 0.017 14.8 2.6 7.7 6.5 0.0 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME29224.1 - 0.027 14.0 1.2 0.2 11.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME29224.1 - 0.22 11.2 5.7 0.27 10.8 0.5 2.8 1 1 2 3 3 3 0 TPR repeat zf-C3HC4 PF00097.20 EME29224.1 - 0.23 11.1 14.2 0.72 9.5 9.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29224.1 - 1.3 8.8 15.6 4.3 7.1 10.8 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Tat PF00539.13 EME29224.1 - 2.2 7.9 14.2 1.2 8.7 8.2 1.8 1 1 0 1 1 1 0 Transactivating regulatory protein (Tat) zf-RING_2 PF13639.1 EME29224.1 - 6.2 6.7 16.8 4.6 7.1 9.6 2.4 2 1 1 3 3 3 0 Ring finger domain TPR_12 PF13424.1 EME29225.1 - 0.003 17.4 0.7 0.003 17.4 0.5 2.6 3 1 0 3 3 3 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EME29225.1 - 0.015 15.3 14.2 0.015 15.3 9.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EME29225.1 - 0.025 14.4 4.1 0.21 11.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME29225.1 - 0.035 13.8 0.6 0.18 11.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME29225.1 - 0.044 13.4 1.3 0.21 11.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME29225.1 - 0.12 12.2 1.4 13 5.9 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EME29225.1 - 0.19 11.4 14.2 0.76 9.4 9.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EME29225.1 - 1.1 8.9 6.2 0.77 9.4 0.3 2.9 2 1 1 3 3 3 0 TPR repeat Tat PF00539.13 EME29225.1 - 2.3 7.9 14.2 1.3 8.7 8.2 1.8 1 1 0 1 1 1 0 Transactivating regulatory protein (Tat) zf-RING_2 PF13639.1 EME29225.1 - 5.8 6.8 16.9 5.6 6.8 9.7 2.5 2 1 1 3 3 3 0 Ring finger domain Ldh_1_C PF02866.13 EME29226.1 - 3.9e-36 124.3 0.0 1.5e-34 119.2 0.0 2.1 1 1 1 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EME29226.1 - 6.4e-33 113.5 0.0 9.1e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain CAP_GLY PF01302.20 EME29227.1 - 2.6e-20 71.8 0.1 3.9e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EME29227.1 - 1e-19 70.5 0.0 1.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF504 PF04457.7 EME29227.1 - 0.078 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF504) Snf7 PF03357.16 EME29228.1 - 2.1e-35 121.6 18.3 2.1e-35 121.6 12.7 2.9 2 1 1 3 3 3 1 Snf7 Vip3A_N PF12495.3 EME29228.1 - 0.016 14.9 0.7 0.046 13.3 0.5 1.8 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal MazG-like PF12643.2 EME29228.1 - 0.18 11.7 4.6 0.2 11.6 0.3 2.7 2 0 0 2 2 2 0 MazG-like family Med28 PF11594.3 EME29228.1 - 2.9 8.1 10.7 1.1 9.5 0.3 2.5 2 0 0 2 2 2 0 Mediator complex subunit 28 Baculo_PEP_C PF04513.7 EME29228.1 - 7.3 6.4 12.2 5 6.9 0.6 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snf7 PF03357.16 EME29229.1 - 2e-35 121.7 18.3 2e-35 121.7 12.7 3.0 2 1 1 3 3 3 1 Snf7 Vip3A_N PF12495.3 EME29229.1 - 0.061 12.9 2.7 0.044 13.4 0.5 1.8 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal MazG-like PF12643.2 EME29229.1 - 0.16 11.8 4.6 0.19 11.6 0.3 2.7 2 0 0 2 2 2 0 MazG-like family DUF3213 PF11491.3 EME29229.1 - 5.6 6.9 7.9 0.44 10.4 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3213) Baculo_PEP_C PF04513.7 EME29229.1 - 6.8 6.5 12.3 4.7 7.0 0.5 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 EME29230.1 - 3e-17 61.7 9.3 7.4e-07 28.8 0.7 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2415 PF10313.4 EME29230.1 - 0.00012 21.6 0.6 0.0028 17.3 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DUF3312 PF11768.3 EME29230.1 - 0.0032 15.7 0.0 0.039 12.1 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) Kelch_2 PF07646.10 EME29230.1 - 0.0072 16.0 0.1 33 4.4 0.0 3.8 3 0 0 3 3 3 1 Kelch motif WD40 PF00400.27 EME29231.1 - 3.9e-17 61.3 9.3 7.7e-07 28.7 0.7 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2415 PF10313.4 EME29231.1 - 0.00013 21.5 0.6 0.0029 17.2 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) DUF3312 PF11768.3 EME29231.1 - 0.0035 15.6 0.0 0.042 12.0 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) Kelch_2 PF07646.10 EME29231.1 - 0.0073 16.0 0.1 35 4.3 0.0 3.9 3 0 0 3 3 3 1 Kelch motif zf-LSD1 PF06943.7 EME29232.1 - 4e-14 51.8 29.6 2.2e-08 33.5 1.8 4.0 4 1 0 4 4 4 3 LSD1 zinc finger C1_1 PF00130.17 EME29232.1 - 0.00067 19.3 17.1 0.026 14.2 0.1 3.2 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EME29232.1 - 0.033 13.9 17.2 0.27 10.9 0.1 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 EME29232.1 - 0.045 13.6 13.7 0.63 9.9 5.7 2.9 2 1 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 EME29232.1 - 0.095 12.5 15.0 33 4.3 8.3 3.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 EME29232.1 - 0.17 11.6 14.9 0.89 9.3 0.8 4.7 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EME29232.1 - 0.31 10.6 15.0 0.85 9.2 0.6 4.6 3 1 1 4 4 4 0 zinc-ribbon domain zf-MYND PF01753.13 EME29232.1 - 2.3 8.1 19.2 3.6 7.5 0.3 4.0 2 1 2 4 4 4 0 MYND finger zf-LSD1 PF06943.7 EME29233.1 - 3e-14 52.3 29.9 1.9e-08 33.7 1.8 4.0 4 1 0 4 4 4 3 LSD1 zinc finger C1_1 PF00130.17 EME29233.1 - 0.0019 17.9 18.6 0.034 13.8 2.3 3.2 2 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EME29233.1 - 0.024 14.3 17.3 0.2 11.3 0.1 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 EME29233.1 - 0.03 14.2 13.8 0.51 10.2 5.8 2.9 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 EME29233.1 - 0.037 13.7 0.4 0.037 13.7 0.3 3.4 2 1 0 2 2 1 0 zinc-RING finger domain DZR PF12773.2 EME29233.1 - 0.063 13.1 15.4 27 4.6 8.4 3.5 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 EME29233.1 - 0.22 11.2 15.9 0.68 9.6 0.7 4.6 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EME29233.1 - 0.33 10.5 15.7 0.73 9.4 0.6 4.6 3 1 1 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EME29233.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 EME29233.1 - 2.3 7.5 0.0 2.3 7.5 0.0 4.2 3 2 1 4 4 4 0 TFIIB zinc-binding zf-MYND PF01753.13 EME29233.1 - 2.5 8.0 20.0 3 7.7 0.3 4.0 2 1 2 4 4 4 0 MYND finger adh_short PF00106.20 EME29234.1 - 6.4e-16 58.7 0.2 1.2e-15 57.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME29234.1 - 2.3e-06 27.4 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME29234.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EME29234.1 - 0.0043 16.7 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EME29234.1 - 0.069 13.4 0.1 0.18 12.0 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Xan_ur_permease PF00860.15 EME29236.1 - 0.00078 18.0 11.3 0.00078 18.0 7.8 1.6 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 EME29236.1 - 0.0014 17.6 6.4 0.0014 17.6 4.5 2.3 1 1 0 2 2 2 1 Sulfate transporter family EcsB PF05975.7 EME29236.1 - 0.05 12.0 6.7 0.0067 14.9 1.7 1.6 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Zip PF02535.17 EME29236.1 - 0.59 9.0 5.1 0.32 9.9 1.2 2.0 1 1 1 2 2 2 0 ZIP Zinc transporter Xan_ur_permease PF00860.15 EME29237.1 - 6.6e-06 24.8 8.7 8.9e-06 24.4 6.0 1.3 1 0 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 EME29237.1 - 6.1e-05 22.1 3.2 6.1e-05 22.1 2.2 2.2 1 1 0 2 2 2 1 Sulfate transporter family PTPS_related PF10131.4 EME29237.1 - 0.032 12.3 1.7 0.043 11.9 1.2 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Zip PF02535.17 EME29237.1 - 1.6 7.6 5.5 0.24 10.3 1.1 1.7 2 1 0 2 2 2 0 ZIP Zinc transporter Epimerase PF01370.16 EME29238.1 - 4.1e-43 147.4 0.0 5.5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME29238.1 - 5.8e-10 38.5 0.0 2.6e-09 36.4 0.0 1.8 1 1 1 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EME29238.1 - 7.8e-08 31.3 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME29238.1 - 1.7e-06 27.1 0.0 2.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EME29238.1 - 4.2e-06 26.7 0.1 8.8e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase_Csub PF13950.1 EME29238.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit KR PF08659.5 EME29238.1 - 0.00044 19.9 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EME29238.1 - 0.00075 18.5 0.5 0.01 14.8 0.3 2.0 1 1 0 1 1 1 1 Male sterility protein Mod_r PF07200.8 EME29239.1 - 0.00096 19.0 9.2 0.0024 17.8 6.4 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ADH_N PF08240.7 EME29240.1 - 3.2e-08 33.2 0.1 9e-08 31.8 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME29240.1 - 1e-05 25.1 0.0 2.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME29240.1 - 6.3e-05 23.8 0.0 0.0017 19.2 0.0 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase SRPRB PF09439.5 EME29241.1 - 1.8e-18 66.3 0.0 2.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EME29241.1 - 3.8e-09 36.0 0.0 5.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME29241.1 - 2.5e-06 27.9 0.0 3.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME29241.1 - 2.5e-06 26.8 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME29241.1 - 4.9e-06 26.4 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME29241.1 - 7e-05 22.3 0.0 0.00021 20.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EME29241.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Vpu PF00558.14 EME29241.1 - 0.17 11.4 0.6 0.39 10.2 0.4 1.6 1 0 0 1 1 1 0 Vpu protein Peptidase_M16_C PF05193.16 EME29242.1 - 1.8e-17 63.5 0.0 1.2e-11 44.6 0.0 3.3 2 1 1 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME29242.1 - 2e-06 27.6 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Shikimate_DH PF01488.15 EME29245.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EME29246.1 - 1.2e-90 304.2 36.3 1.5e-90 303.9 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29246.1 - 1.3e-20 73.4 25.5 1.3e-20 73.4 17.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3493 PF11998.3 EME29246.1 - 0.27 11.1 0.1 0.27 11.1 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3493) DUF3337 PF11816.3 EME29247.1 - 1.1e-44 153.2 0.0 1.5e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EME29247.1 - 1e-33 113.9 18.9 5.1e-08 32.4 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME29247.1 - 0.0017 17.1 3.8 1.3 7.6 0.0 3.9 1 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EME29247.1 - 0.0026 15.9 5.0 0.9 7.5 0.1 3.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF377 PF04041.8 EME29248.1 - 0.004 15.9 0.0 0.09 11.4 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF377) DUF1620 PF07774.8 EME29249.1 - 4.4e-23 81.6 0.0 8.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EME29249.1 - 0.00044 19.7 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EME29249.1 - 0.11 12.0 0.2 65 3.3 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1620 PF07774.8 EME29250.1 - 4.9e-20 71.7 0.0 3.1e-18 65.8 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EME29250.1 - 0.00046 19.7 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EME29250.1 - 0.12 11.9 0.2 66 3.3 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat MIP PF00230.15 EME29251.1 - 5.1e-32 111.1 10.9 6.8e-32 110.7 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein IPP-2 PF04979.9 EME29252.1 - 5.2e-13 49.3 10.4 8.3e-13 48.7 6.7 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3403 PF11883.3 EME29252.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) SQS_PSY PF00494.14 EME29253.1 - 3.7e-72 242.8 0.7 4.6e-72 242.5 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Mur_ligase_M PF08245.7 EME29254.1 - 5.5e-08 33.0 0.2 2.3e-07 31.0 0.2 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EME29254.1 - 7.6e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain HCV_NS5a_C PF12941.2 EME29255.1 - 0.026 14.0 2.4 0.04 13.4 1.6 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region LSM PF01423.17 EME29256.1 - 7.6e-13 47.8 0.0 1.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EME29256.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EME29256.1 - 0.0069 16.2 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain S6PP PF05116.8 EME29257.1 - 3.7e-54 183.6 0.1 4.2e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EME29257.1 - 7.5e-15 55.1 0.0 9.6e-10 38.4 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EME29257.1 - 0.00064 18.7 0.0 0.00092 18.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.11 EME29260.1 - 2.4e-21 75.8 45.4 3.1e-20 72.1 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EME29260.1 - 0.00032 20.6 2.3 0.00032 20.6 1.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_3 PF05977.8 EME29260.1 - 0.56 8.2 11.2 0.039 12.0 2.3 2.2 1 1 1 2 2 2 0 Transmembrane secretion effector CD20 PF04103.10 EME29261.1 - 0.0067 16.3 4.4 0.0095 15.8 3.1 1.2 1 0 0 1 1 1 1 CD20-like family GTP_EFTU PF00009.22 EME29262.1 - 1.7e-65 220.0 0.0 2.7e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME29262.1 - 1e-38 131.5 0.0 1.9e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EME29262.1 - 4.2e-34 116.2 0.0 9e-34 115.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EME29262.1 - 1e-27 95.7 0.0 2.3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME29262.1 - 1.9e-18 66.3 0.3 4e-18 65.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME29262.1 - 0.0037 17.2 0.0 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EME29262.1 - 0.023 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family E2_bind PF08825.5 EME29262.1 - 0.059 13.1 0.4 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 E2 binding domain Exo_endo_phos PF03372.18 EME29263.1 - 9.9e-26 91.1 0.2 1.5e-25 90.5 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EME29263.1 - 5.4e-09 35.8 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M22 PF00814.20 EME29264.1 - 2.4e-57 194.4 0.0 2.7e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PP_kinase_C PF13090.1 EME29265.1 - 2.4e-129 430.9 0.0 3.7e-129 430.3 0.0 1.2 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain PP_kinase PF02503.12 EME29265.1 - 5.1e-51 173.1 0.6 8.6e-51 172.3 0.4 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.1 EME29265.1 - 3.1e-19 69.0 0.4 3.3e-17 62.5 0.3 2.7 1 1 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.1 EME29265.1 - 3.3e-13 49.4 0.1 5.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain NUDIX PF00293.23 EME29265.1 - 4.4e-10 39.3 0.5 1.2e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 NUDIX domain PP_kinase_C PF13090.1 EME29266.1 - 2.2e-129 431.0 0.0 3.3e-129 430.5 0.0 1.2 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain PP_kinase PF02503.12 EME29266.1 - 4.7e-51 173.2 0.6 7.9e-51 172.5 0.4 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.1 EME29266.1 - 2.8e-19 69.2 0.4 3.1e-17 62.6 0.3 2.6 1 1 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.1 EME29266.1 - 2.9e-13 49.6 0.1 5.4e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain NUDIX PF00293.23 EME29266.1 - 3.3e-08 33.2 0.1 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Sugar_tr PF00083.19 EME29267.1 - 3.1e-41 141.4 29.4 1.8e-37 129.0 20.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29267.1 - 5.2e-23 81.3 29.6 7.6e-19 67.6 20.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME29267.1 - 4.5e-06 25.3 19.9 0.0013 17.1 0.0 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein BT1 PF03092.11 EME29267.1 - 0.12 11.1 6.9 0.17 10.5 2.5 2.5 2 1 0 2 2 2 0 BT1 family TCR_zetazeta PF11628.3 EME29267.1 - 0.31 10.5 0.1 0.31 10.5 0.1 3.6 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 zeta chain LRR_6 PF13516.1 EME29268.1 - 1.3e-12 46.4 8.3 0.0032 17.3 0.0 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 EME29268.1 - 3.6e-07 29.2 9.3 0.61 10.3 0.0 6.4 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.2 EME29268.1 - 7.6e-07 28.6 3.3 0.038 13.6 0.0 4.5 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EME29268.1 - 1.1e-05 24.7 10.3 1.7 9.1 0.0 6.7 7 0 0 7 7 7 1 Leucine rich repeat LRR_8 PF13855.1 EME29268.1 - 0.00027 20.6 3.7 0.03 14.0 0.3 4.1 2 1 3 5 5 5 2 Leucine rich repeat F-box PF00646.28 EME29268.1 - 0.077 12.6 2.3 0.11 12.1 0.3 2.5 2 1 0 2 2 2 0 F-box domain EF-hand_4 PF12763.2 EME29269.1 - 2e-20 72.4 0.0 1.5e-11 43.9 0.0 2.7 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand SYCE1 PF15233.1 EME29269.1 - 0.00032 20.6 2.4 0.00035 20.5 0.4 1.8 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 EF-hand_1 PF00036.27 EME29269.1 - 0.0005 19.1 0.2 0.049 12.9 0.0 3.0 3 0 0 3 3 3 1 EF hand ATG16 PF08614.6 EME29269.1 - 0.0021 17.9 1.1 0.0021 17.9 0.8 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) EF-hand_7 PF13499.1 EME29269.1 - 0.014 15.5 0.0 1.6 8.9 0.0 3.0 2 1 0 2 2 2 0 EF-hand domain pair EMP24_GP25L PF01105.19 EME29269.1 - 0.039 13.6 0.5 0.064 12.9 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Atg14 PF10186.4 EME29269.1 - 0.069 12.0 0.5 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBD PF12845.2 EME29269.1 - 0.079 12.5 0.3 2.2 7.8 0.2 2.5 2 0 0 2 2 2 0 TBD domain DUF4407 PF14362.1 EME29269.1 - 0.11 11.4 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EF-hand_6 PF13405.1 EME29269.1 - 0.15 12.0 0.2 18 5.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DUF972 PF06156.8 EME29269.1 - 0.17 12.2 1.7 0.38 11.1 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Tnp_P_element PF12017.3 EME29269.1 - 0.43 9.7 1.6 0.83 8.8 1.1 1.4 1 0 0 1 1 1 0 Transposase protein GrpE PF01025.14 EME29269.1 - 0.97 8.9 3.7 1.7 8.1 2.6 1.3 1 0 0 1 1 1 0 GrpE APG6 PF04111.7 EME29269.1 - 1.7 7.6 5.2 3.1 6.7 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 EME29269.1 - 4.2 7.1 9.5 0.074 12.8 1.5 1.8 2 0 0 2 2 2 0 Prefoldin subunit FA_desaturase PF00487.19 EME29270.1 - 9.2e-31 107.2 34.7 9.2e-31 107.2 24.1 1.3 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EME29270.1 - 0.0062 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CobD_Cbib PF03186.8 EME29270.1 - 0.044 12.8 0.1 0.044 12.8 0.1 1.4 2 0 0 2 2 2 0 CobD/Cbib protein adh_short PF00106.20 EME29271.1 - 3.5e-21 75.8 0.1 5.2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME29271.1 - 8.8e-09 35.4 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME29271.1 - 1e-06 28.5 0.1 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EME29271.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EME29271.1 - 0.003 16.4 0.0 0.0057 15.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EME29271.1 - 0.0037 17.2 0.1 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME29271.1 - 0.0057 16.1 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME29271.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EME29271.1 - 0.12 11.5 0.1 0.59 9.2 0.0 2.1 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) AIF_C PF14721.1 EME29272.1 - 5.5e-21 75.1 1.0 5.1e-13 49.4 0.1 2.6 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 EME29272.1 - 1.1e-19 71.1 0.0 2.1e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME29272.1 - 5.1e-10 39.6 0.0 5.6e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME29272.1 - 3.4e-05 22.9 0.0 0.083 11.7 0.0 3.4 1 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME29272.1 - 0.0014 18.4 0.0 2.6 7.7 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME29272.1 - 0.0057 16.7 0.0 0.56 10.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EME29272.1 - 0.038 14.2 0.0 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2201 PF09967.4 EME29272.1 - 0.049 13.6 0.2 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 VWA-like domain (DUF2201) DUF1818 PF08848.6 EME29273.1 - 1.4e-09 37.9 0.2 0.00032 20.7 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1818) DUF964 PF06133.6 EME29273.1 - 0.019 14.9 1.6 0.039 13.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF964) TAF8_C PF10406.4 EME29273.1 - 0.044 13.8 0.7 0.11 12.5 0.5 1.7 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Laminin_I PF06008.9 EME29273.1 - 0.045 13.0 1.6 0.046 13.0 0.2 1.7 2 0 0 2 2 2 0 Laminin Domain I AF0941-like PF14591.1 EME29273.1 - 0.062 13.3 0.2 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 AF0941-like HALZ PF02183.13 EME29273.1 - 0.15 11.8 2.0 0.16 11.6 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlxA PF14282.1 EME29273.1 - 1.1 9.2 6.3 0.78 9.7 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF747 PF05346.6 EME29274.1 - 5.2e-78 262.4 21.4 7.2e-78 261.9 14.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RVT_1 PF00078.22 EME29274.1 - 0.012 15.0 0.9 0.022 14.1 0.1 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF747 PF05346.6 EME29275.1 - 8.8e-78 261.6 24.3 1.2e-77 261.2 16.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RVT_1 PF00078.22 EME29275.1 - 0.0095 15.3 0.6 0.023 14.0 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BEN PF10523.4 EME29276.1 - 0.0041 17.1 0.1 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 BEN domain peroxidase PF00141.18 EME29277.1 - 7.8e-51 172.7 0.0 1.2e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Aldedh PF00171.17 EME29278.1 - 1.2e-127 426.1 0.1 1.4e-127 425.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UbiA PF01040.13 EME29279.1 - 6.1e-32 110.8 21.3 8.9e-32 110.3 14.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family AOX PF01786.12 EME29279.1 - 0.082 12.3 0.1 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Alternative oxidase DUF4400 PF14348.1 EME29279.1 - 4.6 6.5 19.2 1.8 7.9 5.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) SCO1-SenC PF02630.9 EME29280.1 - 4.2e-55 186.0 0.1 6e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EME29280.1 - 2.6e-05 24.2 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EME29280.1 - 6.4e-05 22.6 0.1 0.00013 21.6 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME29280.1 - 0.004 16.7 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin SBDS PF01172.13 EME29281.1 - 1.1e-20 73.2 1.0 2.6e-20 72.0 0.7 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EME29281.1 - 2.4e-16 59.5 0.8 1.2e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain MinE PF03776.9 EME29281.1 - 0.2 11.1 1.2 9.9 5.7 0.1 2.5 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE TruB_N PF01509.13 EME29282.1 - 5.8e-51 172.5 0.0 8.1e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_N PF01509.13 EME29283.1 - 4.1e-51 173.0 0.0 5.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Helicase_C_2 PF13307.1 EME29284.1 - 3e-58 196.4 0.0 9.1e-58 194.8 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME29284.1 - 5.3e-46 156.2 5.7 1.1e-45 155.1 4.0 1.6 1 0 0 1 1 1 1 DEAD_2 MMtag PF10159.4 EME29284.1 - 4.9e-22 77.7 0.9 1.9e-21 75.8 0.6 2.1 1 0 0 1 1 1 1 Kinase phosphorylation protein DEAD PF00270.24 EME29284.1 - 1.9e-06 27.4 0.1 3.7e-05 23.2 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EME29284.1 - 0.00045 19.5 0.1 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EME29284.1 - 0.00089 18.8 0.9 0.00089 18.8 0.6 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EME29284.1 - 0.26 11.0 5.5 0.29 10.9 0.0 3.0 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Longin PF13774.1 EME29285.1 - 6.1e-18 64.1 0.0 1.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EME29285.1 - 5.7e-14 51.4 0.3 9.8e-14 50.7 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin MIS13 PF08202.6 EME29285.1 - 0.0043 16.1 0.4 0.006 15.6 0.3 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Herpes_teg_N PF04843.7 EME29285.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region TFIIE_beta PF02186.10 EME29286.1 - 7.3e-09 35.4 0.1 1.2e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain HTH_11 PF08279.7 EME29286.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 HTH domain BBE PF08031.7 EME29286.1 - 0.1 12.5 0.1 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Berberine and berberine like DLH PF01738.13 EME29287.1 - 8.7e-48 162.4 0.0 1.1e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME29287.1 - 3.1e-12 46.4 0.0 4.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EME29287.1 - 1.4e-10 41.2 0.8 2.1e-06 27.5 0.1 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 EME29287.1 - 4.1e-09 36.6 0.1 1.5e-06 28.2 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME29287.1 - 2.5e-07 30.4 0.0 3.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EME29287.1 - 0.00016 21.3 0.4 0.017 14.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EME29287.1 - 0.00041 18.9 0.0 0.00056 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EME29287.1 - 0.0011 18.1 0.2 0.71 9.0 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME29287.1 - 0.0057 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EME29287.1 - 0.068 12.5 0.2 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DUF2048 PF09752.4 EME29287.1 - 0.1 11.4 0.2 0.39 9.5 0.1 1.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2048) DUF2974 PF11187.3 EME29287.1 - 0.16 11.3 0.1 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) CMD PF02627.15 EME29288.1 - 1.9e-07 30.8 0.0 6e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Podoplanin PF05808.6 EME29289.1 - 5.7 6.4 7.4 13 5.2 5.1 1.5 1 0 0 1 1 1 0 Podoplanin ARID PF01388.16 EME29290.1 - 0.0012 18.5 2.5 1 9.2 0.0 4.2 3 2 1 5 5 5 2 ARID/BRIGHT DNA binding domain DUF2930 PF11152.3 EME29291.1 - 5e-31 107.3 0.1 6.4e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2930) UbiA PF01040.13 EME29292.1 - 1.8e-30 106.0 19.3 2.3e-30 105.6 13.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Myb_DNA-bind_6 PF13921.1 EME29293.1 - 4.3e-31 106.7 18.9 3.1e-08 33.6 0.1 5.9 4 1 2 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME29293.1 - 2.4e-29 101.1 10.4 1.2e-09 38.0 0.0 6.4 6 1 0 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.5 EME29293.1 - 7e-05 22.5 0.8 0.15 11.8 0.0 3.6 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.3 EME29293.1 - 0.00076 19.3 0.2 0.81 9.6 0.2 3.4 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_38 PF13936.1 EME29293.1 - 0.018 14.5 0.2 0.059 12.9 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 EME29293.1 - 0.021 14.2 0.4 5.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.1 EME29293.1 - 0.039 14.7 1.5 1.4 9.8 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 EME29293.1 - 1.1 8.8 4.8 24 4.5 0.0 3.8 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain GCK PF07802.6 EME29294.1 - 6.4e-07 29.4 4.8 9.5e-07 28.8 2.8 1.7 1 1 0 1 1 1 1 GCK domain CHCH PF06747.8 EME29294.1 - 5.6e-06 26.1 2.7 1.5e-05 24.7 1.9 1.7 1 0 0 1 1 1 1 CHCH domain NT-C2 PF10358.4 EME29295.1 - 6.6e-12 45.1 0.4 2.3e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_MLP1_2 PF07926.7 EME29295.1 - 0.85 9.3 41.7 0.066 12.9 2.7 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EME29295.1 - 2.2 6.8 34.9 0.037 12.6 6.9 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Rootletin PF15035.1 EME29295.1 - 3.7 7.4 45.8 1.8e+02 1.9 15.4 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion NuA4 PF09340.5 EME29296.1 - 3.4e-23 81.0 0.1 5.6e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Angiomotin_C PF12240.3 EME29296.1 - 0.053 13.0 0.8 0.082 12.3 0.5 1.4 1 1 0 1 1 1 0 Angiomotin C terminal WHEP-TRS PF00458.15 EME29296.1 - 0.47 10.1 3.0 0.35 10.5 0.7 1.8 2 0 0 2 2 2 0 WHEP-TRS domain NuA4 PF09340.5 EME29297.1 - 3.4e-23 81.0 0.1 5.6e-23 80.3 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Angiomotin_C PF12240.3 EME29297.1 - 0.053 13.0 0.8 0.082 12.3 0.5 1.4 1 1 0 1 1 1 0 Angiomotin C terminal WHEP-TRS PF00458.15 EME29297.1 - 0.47 10.1 3.0 0.35 10.5 0.7 1.8 2 0 0 2 2 2 0 WHEP-TRS domain Matrilin_ccoil PF10393.4 EME29298.1 - 0.017 14.4 1.1 0.053 12.8 0.3 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Uds1 PF15456.1 EME29298.1 - 0.029 14.3 1.3 0.029 14.3 0.9 2.4 3 0 0 3 3 3 0 Up-regulated During Septation A2L_zn_ribbon PF08792.5 EME29298.1 - 0.036 13.5 0.3 0.11 11.9 0.2 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain Baculo_PEP_C PF04513.7 EME29298.1 - 0.2 11.4 4.7 7.7 6.3 0.1 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.6 EME29298.1 - 0.36 10.0 7.2 0.056 12.7 1.6 2.1 2 1 0 2 2 2 0 Allexivirus 40kDa protein Sugar_tr PF00083.19 EME29299.1 - 1.1e-52 179.1 3.7 1.5e-52 178.7 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29299.1 - 6.1e-22 77.8 5.7 8.4e-22 77.3 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME29299.1 - 4.9e-06 25.0 3.5 6.1e-06 24.7 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EME29299.1 - 0.0004 18.9 2.8 0.0004 18.9 1.9 2.1 2 1 1 3 3 3 1 MFS/sugar transport protein NADHdeh_related PF10125.4 EME29299.1 - 0.045 12.8 1.0 0.086 11.9 0.7 1.5 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein MFS_3 PF05977.8 EME29299.1 - 0.047 11.7 2.8 0.065 11.3 1.9 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF4345 PF14248.1 EME29299.1 - 0.33 10.3 10.0 0.03 13.7 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Sugar_tr PF00083.19 EME29300.1 - 1.1e-27 96.6 13.8 1.3e-27 96.5 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 EME29301.1 - 5.1e-81 272.5 25.9 7.3e-81 272.0 18.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29301.1 - 4.3e-26 91.4 31.0 4.3e-26 91.4 21.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME29301.1 - 9.5e-07 27.3 4.0 1.9e-06 26.3 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF947 PF06102.7 EME29301.1 - 0.16 11.7 0.3 0.24 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Phage_holin_2 PF04550.7 EME29301.1 - 0.27 11.3 5.4 0.37 10.9 0.2 3.1 3 0 0 3 3 3 0 Phage holin family 2 MFS_3 PF05977.8 EME29301.1 - 0.28 9.2 6.7 0.44 8.5 4.6 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector RNase_PH PF01138.16 EME29302.1 - 1e-34 119.7 0.0 2.2e-16 60.3 0.0 2.8 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 S1 PF00575.18 EME29302.1 - 6.7e-17 61.3 2.0 1.7e-16 60.0 0.6 2.3 1 1 1 2 2 2 1 S1 RNA binding domain RNase_PH_C PF03725.10 EME29302.1 - 3e-16 59.0 7.1 8e-10 38.5 0.5 2.7 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 PNPase PF03726.9 EME29302.1 - 6.6e-11 42.3 0.6 2.2e-10 40.6 0.4 2.0 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.24 EME29302.1 - 6.4e-07 28.9 0.4 2e-06 27.3 0.3 1.9 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EME29302.1 - 0.031 13.9 1.1 0.086 12.5 0.8 1.8 1 0 0 1 1 1 0 KH domain Drc1-Sld2 PF11719.3 EME29303.1 - 0.0043 16.2 0.1 0.0045 16.1 0.0 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Hydrophobin_2 PF06766.6 EME29303.1 - 0.042 13.5 0.3 0.099 12.3 0.2 1.7 1 0 0 1 1 1 0 Fungal hydrophobin HEAT PF02985.17 EME29305.1 - 2e-32 108.3 23.7 0.0043 17.0 0.0 17.6 19 0 0 19 19 19 7 HEAT repeat HEAT_2 PF13646.1 EME29305.1 - 7e-28 96.7 23.3 1.9e-06 28.0 0.1 13.3 9 4 5 14 14 14 6 HEAT repeats HEAT_EZ PF13513.1 EME29305.1 - 5.7e-16 58.4 24.3 0.00056 20.3 0.0 12.8 13 2 2 15 15 15 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME29305.1 - 6.1e-13 48.9 0.1 0.0053 17.1 0.0 9.0 8 2 3 11 11 11 3 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EME29305.1 - 0.014 15.3 0.9 25 4.9 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Caudo_TAP PF02413.12 EME29305.1 - 6.6 6.9 10.7 0.79 9.9 2.2 2.6 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein CAP_GLY PF01302.20 EME29306.1 - 4.3e-19 67.9 0.2 7.6e-19 67.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EME29306.1 - 2.1e-18 65.4 14.1 7.1e-07 28.7 0.2 5.6 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME29306.1 - 6.9e-12 44.9 16.7 0.00013 21.6 0.5 5.8 5 2 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EME29306.1 - 1.7e-08 33.3 11.9 1.3 9.3 0.0 7.0 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 EME29306.1 - 3.5e-07 29.3 6.3 2.3 8.8 0.0 7.2 8 0 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 EME29306.1 - 3.1e-06 26.6 9.1 6.6 7.1 0.2 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_2 PF07723.8 EME29306.1 - 0.052 14.0 2.0 1.1e+02 3.5 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat DSHCT PF08148.7 EME29307.1 - 3e-31 108.0 0.1 7.4e-31 106.7 0.1 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EME29307.1 - 1.7e-18 66.7 0.0 4.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EME29307.1 - 2.2e-11 43.4 0.4 4.2e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.26 EME29307.1 - 1.1e-07 31.5 0.0 5.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME29307.1 - 0.00077 19.3 0.2 0.0051 16.6 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit FMN_dh PF01070.13 EME29309.1 - 2.8e-111 371.8 0.0 3.2e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EME29309.1 - 5.8e-08 32.0 0.1 8.8e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME29309.1 - 8.2e-06 24.9 0.0 2.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EME29309.1 - 0.00092 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EME29309.1 - 0.001 18.2 0.0 0.041 12.9 0.0 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EME29309.1 - 0.0024 17.1 0.0 0.047 12.9 0.0 2.5 3 0 0 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EME29309.1 - 0.12 11.2 0.1 5 5.8 0.0 2.8 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) AAA_14 PF13173.1 EME29310.1 - 0.038 13.8 0.1 0.14 12.0 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 EME29310.1 - 0.042 13.2 0.0 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EME29311.1 - 2.2e-15 56.0 0.0 3.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EME29311.1 - 4.3e-13 48.4 12.3 7e-07 28.8 0.9 2.4 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.1 EME29311.1 - 2.5e-11 43.2 0.0 3.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29311.1 - 5.6e-11 42.2 0.0 8.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 EME29311.1 - 7.6e-07 28.6 2.9 0.0038 16.8 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EME29311.1 - 0.0058 16.2 0.6 0.0058 16.2 0.4 2.8 2 1 1 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.1 EME29311.1 - 0.0099 15.5 7.9 0.57 9.9 1.4 2.6 1 1 1 2 2 2 2 Zinc knuckle DUF1660 PF07874.6 EME29311.1 - 0.12 12.6 0.7 0.38 11.0 0.5 1.8 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-CCHC_2 PF13696.1 EME29311.1 - 7.8 6.0 16.1 2.4 7.7 0.6 3.0 2 1 1 3 3 3 0 Zinc knuckle DUF427 PF04248.7 EME29312.1 - 1.7e-09 37.1 0.0 2.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Peptidase_M24 PF00557.19 EME29313.1 - 1.2e-27 96.8 0.3 1.7e-27 96.3 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PfkB PF00294.19 EME29314.1 - 6.8e-61 206.0 0.1 8e-61 205.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EME29314.1 - 0.0098 15.1 0.1 0.059 12.5 0.1 2.1 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase MgtE PF01769.11 EME29316.1 - 1e-06 29.0 4.4 8.6e-06 26.0 0.6 2.3 1 1 1 2 2 2 2 Divalent cation transporter MgtE PF01769.11 EME29317.1 - 8.6e-08 32.5 4.6 1.8e-06 28.3 0.7 2.2 1 1 1 2 2 2 2 Divalent cation transporter Sugar_tr PF00083.19 EME29318.1 - 7.7e-85 285.1 23.7 1.2e-84 284.5 16.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29318.1 - 6.2e-23 81.0 25.6 6.2e-23 81.0 17.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME29318.1 - 6.6e-09 34.5 0.6 1e-08 33.8 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EME29318.1 - 0.036 14.1 4.3 0.12 12.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Folate_carrier PF01770.13 EME29318.1 - 0.63 8.4 5.0 0.057 11.9 0.1 1.8 2 0 0 2 2 2 0 Reduced folate carrier Pkinase PF00069.20 EME29319.1 - 1.7e-69 233.9 0.0 1.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29319.1 - 8.9e-35 119.9 0.0 3.2e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME29319.1 - 0.00036 20.3 1.9 0.25 11.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME29319.1 - 0.0032 16.4 0.0 0.51 9.2 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EME29319.1 - 0.0068 15.5 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EME29319.1 - 0.013 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MgtE_N PF03448.12 EME29319.1 - 0.06 13.6 0.2 0.75 10.1 0.0 2.4 3 0 0 3 3 3 0 MgtE intracellular N domain DUF1241 PF06840.6 EME29319.1 - 0.063 12.5 0.1 0.17 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) RIO1 PF01163.17 EME29319.1 - 0.066 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EME29319.1 - 0.099 12.2 0.2 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L37ae PF01780.14 EME29320.1 - 3.9e-38 129.2 9.8 8.7e-38 128.0 6.8 1.6 1 0 0 1 1 1 1 Ribosomal L37ae protein family WD40 PF00400.27 EME29320.1 - 1.1e-36 123.4 10.8 9.9e-10 37.9 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME29320.1 - 0.00092 17.4 0.4 0.2 9.7 0.3 2.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME29320.1 - 0.02 13.6 3.9 0.08 11.6 0.1 2.4 2 1 0 2 2 2 0 Nup133 N terminal like Rsm1 PF08600.5 EME29320.1 - 0.043 13.6 1.3 0.13 12.0 0.9 1.9 1 0 0 1 1 1 0 Rsm1-like Acid_PPase PF12689.2 EME29321.1 - 1.8e-50 170.8 0.0 2.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EME29321.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EME29321.1 - 0.0019 17.8 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 EME29322.1 - 9.9e-42 142.9 53.6 7e-32 110.5 25.5 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME29322.1 - 0.00084 18.0 30.0 0.0043 15.6 4.2 3.9 2 2 1 3 3 3 3 Sugar (and other) transporter PsbI PF02532.9 EME29322.1 - 7.9 6.1 10.2 0.94 9.1 3.1 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) zf-CCCH PF00642.19 EME29323.1 - 0.12 12.0 0.8 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribonucleas_3_3 PF14622.1 EME29325.1 - 1.8e-15 56.9 0.0 6.6e-11 42.2 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EME29325.1 - 1e-05 25.9 0.0 0.88 10.0 0.0 3.7 4 0 0 4 4 4 2 Ribonuclease III domain dsrm PF00035.20 EME29325.1 - 0.016 15.7 0.1 2.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding motif PIP5K PF01504.13 EME29326.1 - 4.5e-69 232.3 0.0 7.1e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Apt1 PF10351.4 EME29327.1 - 4.1e-38 131.4 8.1 4.1e-38 131.4 5.6 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 EME29327.1 - 3.9e-16 59.3 0.0 1.4e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Na_trans_assoc PF06512.8 EME29328.1 - 0.013 15.4 10.0 0.015 15.3 6.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated UPF0370 PF13980.1 EME29328.1 - 0.14 11.9 0.2 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Protamine_P2 PF00841.14 EME29328.1 - 0.3 11.6 1.8 8.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Sperm histone P2 DUF2058 PF09831.4 EME29328.1 - 0.64 9.8 9.7 1.3 8.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) HNF-1_N PF04814.8 EME29328.1 - 3.2 7.8 9.7 0.44 10.6 1.6 2.0 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Asp-B-Hydro_N PF05279.6 EME29328.1 - 4.5 7.0 11.5 5.8 6.6 8.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_E PF05680.7 EME29328.1 - 9.1 6.3 10.0 5 7.1 1.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain Na_trans_assoc PF06512.8 EME29329.1 - 0.013 15.4 10.0 0.015 15.3 6.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated UPF0370 PF13980.1 EME29329.1 - 0.14 11.9 0.2 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Protamine_P2 PF00841.14 EME29329.1 - 0.3 11.6 1.8 8.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Sperm histone P2 DUF2058 PF09831.4 EME29329.1 - 0.64 9.8 9.7 1.3 8.9 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) HNF-1_N PF04814.8 EME29329.1 - 3.2 7.8 9.7 0.44 10.6 1.6 2.0 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Asp-B-Hydro_N PF05279.6 EME29329.1 - 4.5 7.0 11.5 5.8 6.6 8.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_E PF05680.7 EME29329.1 - 9.1 6.3 10.0 5 7.1 1.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain NDUF_B6 PF09782.4 EME29331.1 - 0.05 13.4 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF2393 PF09624.5 EME29331.1 - 0.088 12.3 1.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Sec20 PF03908.8 EME29331.1 - 4 7.2 11.9 18 5.1 0.3 3.4 3 0 0 3 3 3 0 Sec20 DUF2721 PF11026.3 EME29331.1 - 4.8 6.8 8.2 0.53 9.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3278 PF11683.3 EME29331.1 - 4.9 7.1 7.1 0.35 10.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) FmdA_AmdA PF03069.10 EME29332.1 - 5.2e-97 324.8 0.0 6e-97 324.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF2894 PF11445.3 EME29337.1 - 0.041 14.1 0.1 0.044 14.0 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) XG_FTase PF03254.8 EME29338.1 - 0.00056 18.5 0.0 0.41 9.0 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase DPPIV_N PF00930.16 EME29339.1 - 1.9e-13 49.7 0.1 6.1e-12 44.7 0.0 2.3 1 1 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EME29339.1 - 0.043 13.5 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Glycos_transf_1 PF00534.15 EME29340.1 - 2.2e-10 40.2 0.0 1.2e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME29340.1 - 4.6e-05 23.5 0.0 0.00029 21.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME29340.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 VIT1 PF01988.14 EME29341.1 - 5.8e-73 244.8 2.9 7.2e-73 244.5 2.0 1.1 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 EME29341.1 - 5.9 6.1 7.5 8 5.7 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) VIT1 PF01988.14 EME29342.1 - 5.8e-73 244.8 2.9 7.4e-73 244.5 2.0 1.1 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 EME29342.1 - 6 6.1 7.5 8.1 5.6 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) IP_trans PF02121.13 EME29343.1 - 1.1e-88 296.6 1.6 1.3e-88 296.4 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein zf-Tim10_DDP PF02953.10 EME29344.1 - 1.7e-22 78.4 0.6 2e-22 78.2 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EME29344.1 - 0.039 13.3 0.7 0.049 13.0 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RabGAP-TBC PF00566.13 EME29345.1 - 1.1e-30 106.6 0.0 1.8e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.18 EME29346.1 - 4e-106 354.4 0.1 4e-106 354.4 0.1 2.9 3 1 0 3 3 3 1 Kinesin motor domain DUF2838 PF10998.3 EME29347.1 - 3.6e-31 107.3 8.5 3.6e-31 107.3 5.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.13 EME29347.1 - 0.064 12.7 10.1 0.1 12.1 7.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.10 EME29347.1 - 0.13 11.4 3.4 0.19 10.8 2.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2229 PF09989.4 EME29347.1 - 0.17 11.3 3.2 0.3 10.5 2.2 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) OmpH PF03938.9 EME29347.1 - 0.42 10.5 5.4 0.85 9.5 3.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF349 PF03993.7 EME29347.1 - 7.1 6.8 12.8 16 5.7 1.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Atg14 PF10186.4 EME29347.1 - 9.5 5.0 12.5 16 4.3 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ufm1 PF03671.9 EME29349.1 - 3.5e-44 148.3 0.2 4.2e-44 148.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Aminotran_1_2 PF00155.16 EME29350.1 - 1.1e-80 271.3 0.0 1.3e-80 271.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3436 PF11918.3 EME29351.1 - 0.12 12.5 0.0 0.94 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) PP2C PF00481.16 EME29352.1 - 9.7e-45 152.9 0.1 1.3e-43 149.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME29352.1 - 1.8e-05 24.2 0.9 5e-05 22.8 0.6 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EME29353.1 - 0.004 16.5 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.26 EME29354.1 - 2.6e-08 33.7 0.1 6.6e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME29354.1 - 0.00033 20.6 0.3 0.0013 18.8 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EME29354.1 - 0.037 13.9 0.6 0.12 12.2 0.4 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Rad51 PF08423.6 EME29355.1 - 1.7e-25 89.4 0.0 2.2e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EME29355.1 - 8e-08 31.9 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME29355.1 - 8.3e-06 25.9 0.1 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME29355.1 - 1.4e-05 24.3 0.1 2.8e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 KaiC NACHT PF05729.7 EME29355.1 - 9.6e-05 22.0 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME29355.1 - 0.0029 17.6 0.1 0.0048 16.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EME29355.1 - 0.006 15.4 0.0 0.03 13.1 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain Pkinase PF00069.20 EME29357.1 - 5.6e-70 235.4 0.0 8.9e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29357.1 - 1.6e-30 106.0 0.0 2.7e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME29357.1 - 0.00012 21.1 0.0 0.00052 19.0 0.0 1.9 2 1 1 3 3 3 1 Kinase-like RIO1 PF01163.17 EME29357.1 - 0.021 14.1 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EME29357.1 - 0.062 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EME29357.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF326 PF03860.11 EME29357.1 - 0.39 10.6 2.3 0.75 9.7 1.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) DUF1356 PF07092.7 EME29358.1 - 0.81 8.8 6.0 1.2 8.2 0.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) Not3 PF04065.10 EME29359.1 - 0.021 14.1 0.3 0.04 13.1 0.2 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF4239 PF14023.1 EME29359.1 - 0.046 13.0 0.1 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Mem_trans PF03547.13 EME29360.1 - 3.8e-35 120.9 12.0 4.5e-35 120.6 8.3 1.0 1 0 0 1 1 1 1 Membrane transport protein TM_helix PF05552.7 EME29360.1 - 0.069 12.8 0.5 0.069 12.8 0.4 2.4 3 0 0 3 3 3 0 Conserved TM helix DUF204 PF02659.10 EME29360.1 - 1.3 9.2 7.3 2.3 8.3 0.9 3.4 2 1 0 2 2 2 0 Domain of unknown function DUF COPIIcoated_ERV PF07970.7 EME29361.1 - 2.1e-08 34.0 0.3 3.8e-08 33.2 0.1 1.4 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter GDYXXLXY PF14345.1 EME29361.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 GDYXXLXY protein ERGIC_N PF13850.1 EME29362.1 - 8.4e-16 57.7 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.7 EME29362.1 - 3.6e-11 43.1 4.5 4.9e-11 42.6 3.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Beta-TrCP_D PF12125.3 EME29362.1 - 0.061 12.9 4.7 0.16 11.5 1.9 2.3 2 0 0 2 2 2 0 D domain of beta-TrCP TMPIT PF07851.8 EME29363.1 - 3.2e-73 246.6 11.1 4e-73 246.3 7.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein Mt_ATP-synt_D PF05873.7 EME29363.1 - 0.023 14.3 0.3 0.042 13.4 0.2 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) BBS2_C PF14782.1 EME29363.1 - 0.031 12.8 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF3450 PF11932.3 EME29363.1 - 0.038 13.2 0.7 0.074 12.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1672 PF07901.6 EME29363.1 - 0.059 12.3 0.2 0.087 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Pro-kuma_activ PF09286.6 EME29363.1 - 0.079 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain OEP PF02321.13 EME29363.1 - 0.79 9.2 5.1 0.29 10.7 0.3 2.4 3 0 0 3 3 3 0 Outer membrane efflux protein DUF1749 PF08538.5 EME29364.1 - 4.2e-53 180.1 0.0 5.3e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EME29364.1 - 1.8e-17 63.9 0.0 2.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME29364.1 - 6.4e-11 42.1 0.0 9.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EME29364.1 - 0.019 14.6 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase CNF1 PF05785.7 EME29364.1 - 0.035 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor LCAT PF02450.10 EME29364.1 - 0.044 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase EF-hand_like PF09279.6 EME29364.1 - 0.092 12.7 0.0 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF900 PF05990.7 EME29364.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 EME29364.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Amino_oxidase PF01593.19 EME29365.1 - 5.4e-36 124.6 0.0 6.7e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME29365.1 - 1.5e-14 53.7 1.9 2.4e-14 53.1 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME29365.1 - 3.9e-08 32.5 1.2 1e-05 24.5 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME29365.1 - 6.6e-07 28.5 0.3 4.6e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME29365.1 - 1.4e-05 25.2 0.2 2.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME29365.1 - 2.4e-05 24.3 0.2 8.2e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME29365.1 - 3.8e-05 22.9 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME29365.1 - 5.9e-05 21.7 1.3 6.8e-05 21.5 0.4 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EME29365.1 - 0.00021 21.6 1.9 0.00084 19.6 0.3 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EME29365.1 - 0.00036 19.0 0.2 0.0087 14.4 0.2 2.0 2 0 0 2 2 2 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family Thi4 PF01946.12 EME29365.1 - 0.00046 19.3 0.4 0.0011 18.1 0.2 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EME29365.1 - 0.00053 18.9 0.3 0.0013 17.7 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EME29365.1 - 0.012 14.6 0.4 0.021 13.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EME29365.1 - 0.015 14.9 0.2 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EME29365.1 - 0.016 14.9 0.8 0.031 14.0 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EME29365.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_2 PF03446.10 EME29365.1 - 0.04 13.7 0.1 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.7 EME29365.1 - 0.041 12.7 0.1 0.067 12.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AMP-binding PF00501.23 EME29367.1 - 1.8e-20 72.7 0.1 2.6e-12 45.8 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme AAA PF00004.24 EME29368.1 - 8.5e-44 148.9 0.0 1.1e-39 135.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EME29368.1 - 7.3e-12 45.1 1.5 8.2e-12 45.0 0.1 1.8 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EME29368.1 - 5.4e-06 26.5 0.1 0.0002 21.4 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME29368.1 - 4.7e-05 23.5 0.0 0.002 18.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EME29368.1 - 0.00056 20.7 0.0 0.019 15.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EME29368.1 - 0.0026 17.5 0.0 0.016 14.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME29368.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) UFD1 PF03152.9 EME29368.1 - 0.0047 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_14 PF13173.1 EME29368.1 - 0.014 15.2 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EME29368.1 - 0.023 13.4 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EME29368.1 - 0.024 14.3 0.1 0.096 12.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EME29368.1 - 0.026 14.7 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EME29368.1 - 0.028 14.1 0.0 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase Molydop_binding PF01568.16 EME29368.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RuvB_N PF05496.7 EME29368.1 - 0.033 13.2 0.0 0.094 11.7 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EME29368.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME29368.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 EME29369.1 - 3.9e-06 26.3 7.2 3.9e-06 26.3 5.0 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 EME29369.1 - 0.041 13.2 3.0 0.069 12.5 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) 7TM_GPCR_Srz PF10325.4 EME29369.1 - 0.16 11.0 6.6 0.91 8.5 0.5 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF2269 PF10027.4 EME29369.1 - 1.1 9.0 5.9 6.7 6.4 0.8 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) Ion_trans PF00520.26 EME29369.1 - 2.7 7.2 7.5 1.2 8.3 0.7 2.1 1 1 1 2 2 2 0 Ion transport protein tRNA-synt_1b PF00579.20 EME29370.1 - 6.5e-63 212.5 0.0 7.9e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF421 PF04239.7 EME29370.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF421) PTPA PF03095.10 EME29371.1 - 1.1e-115 386.0 0.0 1.2e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Xpo1 PF08389.7 EME29371.1 - 0.11 12.3 0.3 0.74 9.7 0.2 2.1 1 1 1 2 2 2 0 Exportin 1-like protein Metallophos PF00149.23 EME29372.1 - 2e-42 144.8 0.7 5e-42 143.5 0.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 EME29373.1 - 0.0029 17.2 1.9 0.0029 17.2 1.4 1.7 2 0 0 2 2 2 1 SUR7/PalI family ABC2_membrane_5 PF13346.1 EME29373.1 - 3.6 6.8 14.3 0.43 9.8 4.9 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein NfeD PF01957.13 EME29373.1 - 8.5 6.5 9.5 3.5 7.7 0.0 2.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF1754 PF08555.5 EME29374.1 - 0.062 13.8 0.3 0.074 13.6 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Nbas_N PF15492.1 EME29375.1 - 0.1 11.7 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Hemerythrin PF01814.18 EME29376.1 - 6.5e-30 104.0 12.4 3.6e-14 53.0 0.1 5.4 4 2 2 6 6 6 6 Hemerythrin HHE cation binding domain zinc_ribbon_6 PF14599.1 EME29376.1 - 6.6e-21 73.8 1.7 6.6e-21 73.8 1.2 3.8 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EME29376.1 - 1.8e-14 53.5 18.4 1.8e-14 53.5 12.8 5.5 4 1 1 5 5 5 1 CHY zinc finger zf-RING_2 PF13639.1 EME29376.1 - 1.1e-08 34.8 6.9 1.1e-08 34.8 4.8 5.0 6 1 0 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME29376.1 - 7.9e-06 25.8 8.6 7.9e-06 25.8 6.0 5.6 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29376.1 - 1.8e-05 24.3 7.6 1.8e-05 24.3 5.2 6.4 4 2 1 5 5 5 1 zinc-RING finger domain MMR_HSR1 PF01926.18 EME29377.1 - 4.3e-20 71.8 0.2 1.5e-15 57.1 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 EME29377.1 - 1.1e-16 60.4 21.9 3.9e-16 58.7 15.2 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 EME29377.1 - 1.9e-09 37.0 0.1 1.8e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EME29377.1 - 6.6e-05 23.3 0.6 0.054 14.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EME29377.1 - 0.00037 20.3 10.9 0.0039 17.0 0.0 3.5 2 2 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EME29377.1 - 0.0067 15.6 0.5 0.026 13.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME29377.1 - 0.019 14.4 8.6 0.033 13.6 0.3 3.7 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EME29377.1 - 0.024 14.3 0.0 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME29377.1 - 0.04 13.9 0.4 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EME29377.1 - 0.47 9.1 0.0 0.47 9.1 0.0 2.6 2 1 0 2 2 2 0 ArgK protein Mit_KHE1 PF10173.4 EME29377.1 - 1.2 8.8 10.7 0.97 9.2 5.5 2.0 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related MMR_HSR1 PF01926.18 EME29378.1 - 4.5e-20 71.7 0.2 1.5e-15 57.1 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 EME29378.1 - 9.9e-17 60.6 21.6 3.4e-16 58.9 15.0 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 EME29378.1 - 2e-09 36.9 0.1 1.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EME29378.1 - 7e-05 23.3 0.6 0.055 13.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EME29378.1 - 0.00059 19.7 11.4 0.0062 16.3 0.0 3.5 2 2 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EME29378.1 - 0.007 15.5 0.5 0.027 13.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME29378.1 - 0.022 14.2 8.7 0.034 13.5 0.3 3.7 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EME29378.1 - 0.025 14.2 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME29378.1 - 0.043 13.8 0.4 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EME29378.1 - 0.49 9.1 0.0 0.49 9.1 0.0 2.6 2 1 0 2 2 2 0 ArgK protein Mit_KHE1 PF10173.4 EME29378.1 - 1.3 8.7 10.8 1 9.1 5.5 2.0 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related FHA PF00498.21 EME29379.1 - 2.4e-16 59.5 0.0 7.9e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 FHA domain RRM_1 PF00076.17 EME29379.1 - 8.3e-16 57.3 0.0 4e-15 55.1 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29379.1 - 1.5e-14 53.7 0.0 2.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29379.1 - 5.2e-09 35.8 0.0 1.4e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME29379.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EME29380.1 - 1.1e-15 57.0 0.0 3.7e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29380.1 - 1.3e-14 53.8 0.0 2.4e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29380.1 - 6.6e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 EME29380.1 - 8.4e-05 22.6 0.0 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 FHA domain Nup35_RRM_2 PF14605.1 EME29380.1 - 0.036 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Kinesin PF00225.18 EME29382.1 - 4.5e-73 245.8 0.0 6.7e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF972 PF06156.8 EME29382.1 - 0.0083 16.4 2.5 2.5 8.4 0.2 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF972) DEAD PF00270.24 EME29382.1 - 0.037 13.5 0.1 0.7 9.3 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EME29382.1 - 0.073 13.3 3.4 0.65 10.2 0.4 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EME29382.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribonuc_red_sm PF00268.16 EME29383.1 - 2.2e-118 394.3 0.5 2.8e-118 394.0 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain IFRD PF05004.8 EME29384.1 - 6.5e-11 41.8 1.2 6.5e-11 41.8 0.8 2.5 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 EME29384.1 - 8.3e-07 29.0 0.5 8.3e-07 29.0 0.4 1.8 2 0 0 2 2 2 1 Interferon-related protein conserved region IFRD PF05004.8 EME29385.1 - 6.1e-11 41.9 1.2 6.1e-11 41.9 0.8 2.5 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.7 EME29385.1 - 8e-07 29.1 0.5 8e-07 29.1 0.4 1.9 2 0 0 2 2 2 1 Interferon-related protein conserved region Ribosomal_L6 PF00347.18 EME29387.1 - 1.2e-30 105.7 2.9 1.9e-14 53.9 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PhyH PF05721.8 EME29388.1 - 2.8e-39 135.3 0.0 1.5e-37 129.7 0.0 2.0 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 EME29389.1 - 4.1e-45 154.4 0.0 4.9e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sushi_2 PF09014.5 EME29389.1 - 0.065 13.0 0.1 2.1 8.1 0.0 2.5 1 1 1 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Peptidase_M20 PF01546.23 EME29390.1 - 4e-30 104.7 0.0 5.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME29390.1 - 7e-15 54.7 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain V-ATPase_C PF03223.10 EME29391.1 - 3.1e-82 276.4 1.9 3.6e-82 276.2 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C TrwB_AAD_bind PF10412.4 EME29391.1 - 0.0033 16.0 0.2 0.0051 15.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain GvpL_GvpF PF06386.6 EME29391.1 - 0.024 14.2 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF365 PF04033.7 EME29391.1 - 0.3 11.0 2.4 1.8 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF365) V-ATPase_C PF03223.10 EME29392.1 - 3.8e-83 279.4 1.1 4.2e-83 279.3 0.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C TrwB_AAD_bind PF10412.4 EME29392.1 - 0.0033 16.1 0.1 0.0052 15.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain GvpL_GvpF PF06386.6 EME29392.1 - 0.03 13.8 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF365 PF04033.7 EME29392.1 - 0.34 10.9 2.4 1.9 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF365) WD40 PF00400.27 EME29393.1 - 2.9e-35 118.8 13.9 1e-05 25.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 EME29393.1 - 4.9e-34 116.8 0.1 1.5e-33 115.2 0.1 1.9 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EME29393.1 - 2.4e-20 72.4 0.2 3.5e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 PUL domain NAD_binding_10 PF13460.1 EME29394.1 - 8.4e-19 68.2 0.0 1.3e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME29394.1 - 5.7e-06 25.9 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME29394.1 - 3.1e-05 23.9 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EME29394.1 - 7.9e-05 22.0 0.1 0.0004 19.7 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EME29394.1 - 0.0079 14.9 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4508 PF14969.1 EME29394.1 - 0.014 15.4 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) KR PF08659.5 EME29394.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EME29394.1 - 0.065 13.1 0.8 0.17 11.7 0.5 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EME29394.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase efb-c PF12199.3 EME29394.1 - 0.13 12.0 0.2 1.1 9.1 0.2 2.1 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal DMPK_coil PF08826.5 EME29394.1 - 0.18 11.7 0.2 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF342 PF03961.8 EME29395.1 - 6 5.1 10.0 0.81 8.0 2.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF342) EAP30 PF04157.11 EME29396.1 - 6.6e-51 172.6 0.1 7.6e-51 172.4 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TRAP_alpha PF03896.11 EME29397.1 - 6.7e-16 58.1 1.2 8.1e-16 57.8 0.3 1.5 1 1 1 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Plasmodium_Vir PF05795.6 EME29397.1 - 0.0029 16.8 0.2 0.0041 16.3 0.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Orai-1 PF07856.7 EME29397.1 - 0.0036 16.8 0.2 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 Mediator of CRAC channel activity Ion_trans PF00520.26 EME29397.1 - 0.027 13.7 0.3 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Ion transport protein S1FA PF04689.8 EME29397.1 - 0.14 12.0 4.3 0.19 11.6 0.1 3.0 4 0 0 4 4 4 0 DNA binding protein S1FA DUF2393 PF09624.5 EME29397.1 - 0.14 11.6 1.8 0.26 10.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) UT PF03253.9 EME29397.1 - 0.59 8.9 2.7 4.4 6.0 0.3 2.1 2 0 0 2 2 2 0 Urea transporter DUF3317 PF11779.3 EME29397.1 - 0.91 9.0 5.4 2.4 7.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) IKI3 PF04762.7 EME29398.1 - 7.4e-96 321.9 1.1 2e-84 284.0 0.4 3.6 1 1 1 2 2 2 2 IKI3 family Nucleoporin_N PF08801.6 EME29398.1 - 0.0028 16.4 0.1 0.91 8.2 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like IKI3 PF04762.7 EME29399.1 - 7.4e-96 321.9 1.1 2e-84 284.0 0.4 3.6 1 1 1 2 2 2 2 IKI3 family Nucleoporin_N PF08801.6 EME29399.1 - 0.0028 16.4 0.1 0.91 8.2 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like zf-RING_2 PF13639.1 EME29400.1 - 6.1e-13 48.3 10.7 1.3e-12 47.3 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME29400.1 - 2e-09 37.4 7.2 4.6e-09 36.2 5.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME29400.1 - 7.7e-08 32.2 10.8 1.7e-07 31.1 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME29400.1 - 2.2e-07 30.3 10.3 5.9e-07 29.0 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME29400.1 - 4.3e-07 29.4 7.7 9e-07 28.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29400.1 - 2.8e-06 26.9 9.2 6.9e-06 25.6 6.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME29400.1 - 0.00016 21.3 7.6 0.00057 19.6 5.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3663 PF12404.3 EME29400.1 - 0.0057 16.4 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase Baculo_RING PF05883.6 EME29400.1 - 0.062 13.1 2.5 0.12 12.1 1.7 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 EME29400.1 - 0.074 12.8 1.8 0.19 11.5 1.1 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.2 EME29400.1 - 0.078 13.0 10.4 0.23 11.5 7.2 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EME29400.1 - 0.11 12.2 4.4 0.11 12.1 2.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EME29400.1 - 0.65 9.5 10.0 0.12 11.8 2.6 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-Nse PF11789.3 EME29400.1 - 0.83 9.2 5.9 1.6 8.2 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EME29400.1 - 1.9 8.4 10.5 17 5.4 7.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EME29400.1 - 3.7 7.4 8.6 12 5.8 5.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EME29400.1 - 5.8 6.5 7.8 40 3.9 5.3 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Guanylate_cyc_2 PF09778.4 EME29401.1 - 2.3e-54 183.7 3.1 1.2e-51 174.9 2.2 2.0 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C39 PF03412.10 EME29401.1 - 1.8e-08 34.2 0.0 5.9e-06 26.1 0.0 3.0 1 1 2 3 3 3 1 Peptidase C39 family Peptidase_C39_2 PF13529.1 EME29401.1 - 4.7e-05 23.7 0.0 0.0023 18.3 0.0 2.4 2 1 0 2 2 2 1 Peptidase_C39 like family Adap_comp_sub PF00928.16 EME29402.1 - 4.7e-46 157.0 0.3 6.8e-46 156.4 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Alpha-amylase PF00128.19 EME29403.1 - 9.2e-57 192.8 0.3 1.5e-56 192.1 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain NHL PF01436.16 EME29404.1 - 6e-24 82.7 0.2 1.5e-05 24.7 0.0 5.6 5 0 0 5 5 5 4 NHL repeat Thioredoxin_8 PF13905.1 EME29404.1 - 0.066 13.3 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like RNA_pol_Rpb4 PF03874.11 EME29405.1 - 7.6e-09 35.5 0.1 9.1e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 RNA_pol_Rpb4 PF03874.11 EME29406.1 - 1.6e-11 44.2 0.1 1.8e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 W2 PF02020.13 EME29407.1 - 1e-13 51.0 3.4 1e-13 51.0 2.3 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EME29407.1 - 2.5e-10 39.3 11.4 3.7e-05 23.0 2.5 3.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EME29407.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EME29407.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME29407.1 - 0.035 13.6 9.6 0.035 13.6 1.2 2.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EME29408.1 - 2.1e-10 39.6 11.4 1.3e-05 24.4 2.2 3.7 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EME29408.1 - 0.00048 19.4 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EME29408.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME29408.1 - 0.029 13.9 9.6 0.033 13.7 1.1 2.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Chorein_N PF12624.2 EME29409.1 - 1.2e-20 73.2 0.0 3.3e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EME29409.1 - 0.00066 19.7 0.0 0.0038 17.3 0.0 2.3 3 0 0 3 3 3 1 ATG C terminal domain UBA PF00627.26 EME29409.1 - 0.025 14.4 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain HupE_UreJ PF04955.7 EME29409.1 - 1.2 8.3 0.5 2.5 7.3 0.3 1.4 1 0 0 1 1 1 0 HupE / UreJ protein RRM_1 PF00076.17 EME29410.1 - 3.7e-19 68.1 0.0 5.3e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29410.1 - 4.4e-16 58.6 0.0 5.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29410.1 - 5.5e-09 35.7 0.0 8.1e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI_Csn8 PF10075.4 EME29411.1 - 5.7e-29 100.7 0.3 5.7e-29 100.7 0.2 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EME29411.1 - 1.9e-26 92.9 5.3 3e-26 92.2 3.7 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Med3 PF11593.3 EME29411.1 - 0.14 11.3 1.1 0.19 10.9 0.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L22 PF00237.14 EME29412.1 - 3.1e-18 65.6 0.1 4.4e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 4HBT PF03061.17 EME29413.1 - 6.5e-11 42.2 0.0 9.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DDA1 PF10172.4 EME29414.1 - 0.00023 20.8 0.1 0.00071 19.3 0.1 1.8 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase SAP PF02037.22 EME29414.1 - 0.00048 19.5 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain BRK PF07533.11 EME29415.1 - 8.5e-17 60.3 4.2 3e-08 33.0 0.6 2.3 2 0 0 2 2 2 2 BRK domain V-SNARE PF05008.10 EME29416.1 - 8.7e-06 25.8 13.5 1.9e-05 24.7 3.9 2.9 2 2 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EME29416.1 - 0.0027 17.7 1.5 0.2 11.7 0.1 3.1 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus WXG100 PF06013.7 EME29416.1 - 0.032 14.2 4.8 9.3 6.3 0.1 3.9 2 2 2 4 4 4 0 Proteins of 100 residues with WXG DUF342 PF03961.8 EME29416.1 - 0.11 10.9 6.6 0.13 10.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PilJ PF13675.1 EME29416.1 - 0.13 12.5 6.0 0.52 10.6 1.6 2.5 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Allexi_40kDa PF05549.6 EME29416.1 - 0.14 11.4 2.9 0.17 11.1 1.7 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 EME29416.1 - 0.32 10.1 3.3 0.49 9.5 2.2 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EME29416.1 - 0.36 11.1 5.3 10 6.4 0.2 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ENT PF03735.9 EME29416.1 - 0.36 10.5 6.8 0.18 11.5 2.1 2.4 2 2 0 2 2 2 0 ENT domain DUF1664 PF07889.7 EME29416.1 - 0.57 9.9 7.6 0.61 9.8 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF148 PF02520.12 EME29416.1 - 0.9 9.3 4.2 2.3 8.0 0.1 2.7 1 1 0 2 2 2 0 Domain of unknown function DUF148 DUF1090 PF06476.7 EME29416.1 - 1 9.0 8.4 1.1 8.9 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF745 PF05335.8 EME29416.1 - 1.3 8.5 6.3 0.71 9.3 1.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) IncA PF04156.9 EME29416.1 - 1.7 8.2 21.8 0.39 10.2 7.2 2.1 1 1 1 2 2 2 0 IncA protein DUF2937 PF11157.3 EME29416.1 - 2 7.7 3.8 25 4.1 2.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.5 EME29416.1 - 2.5 8.2 8.7 0.98 9.5 2.4 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Enkurin PF13864.1 EME29416.1 - 2.7 8.2 10.0 2.3 8.4 2.5 2.5 1 1 1 2 2 2 0 Calmodulin-binding DUF2203 PF09969.4 EME29416.1 - 2.8 8.2 6.2 96 3.2 4.3 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FlxA PF14282.1 EME29416.1 - 3.3 7.7 13.2 2.5 8.0 1.0 2.5 1 1 1 2 2 2 0 FlxA-like protein 2-oxoacid_dh PF00198.18 EME29417.1 - 5.2e-82 274.5 0.3 7.3e-82 274.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME29417.1 - 8.3e-38 127.8 17.3 1e-19 69.9 3.7 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EME29417.1 - 3.6e-07 29.7 11.6 0.004 16.7 0.3 4.5 2 2 2 4 4 4 2 Biotin-lipoyl like HlyD_3 PF13437.1 EME29417.1 - 8.2e-06 26.1 6.5 0.0084 16.4 0.1 3.8 2 2 2 4 4 4 3 HlyD family secretion protein GCV_H PF01597.14 EME29417.1 - 2e-05 24.2 7.8 0.0061 16.2 0.5 4.0 2 2 2 4 4 4 2 Glycine cleavage H-protein RnfC_N PF13375.1 EME29417.1 - 0.00017 21.2 6.6 0.069 12.8 0.1 4.1 2 2 2 4 4 4 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EME29417.1 - 0.0084 15.4 8.2 0.45 9.7 0.1 2.5 2 1 0 2 2 2 2 HlyD family secretion protein DUF4182 PF13790.1 EME29417.1 - 0.18 11.6 3.8 9.3 6.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) CAF-1_p150 PF11600.3 EME29417.1 - 7.2 5.9 12.8 13 5.0 8.9 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal tRNA-synt_1c PF00749.16 EME29418.1 - 1.1e-107 359.3 0.0 1.6e-107 358.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EME29418.1 - 5.4e-41 140.1 0.0 2.9e-40 137.7 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EME29418.1 - 2.3e-29 102.0 1.6 3.9e-29 101.2 1.1 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 GLTP PF08718.6 EME29419.1 - 7.3e-36 123.4 0.0 8.8e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) TPR_16 PF13432.1 EME29420.1 - 5.5e-36 122.4 15.0 1.9e-06 28.4 0.0 7.5 4 2 3 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EME29420.1 - 1.1e-33 114.7 21.1 3.9e-06 26.4 0.1 7.8 6 2 2 8 8 8 7 TPR repeat TPR_2 PF07719.12 EME29420.1 - 5.8e-33 110.1 32.4 0.00086 19.0 0.3 12.7 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_17 PF13431.1 EME29420.1 - 1.6e-30 102.7 9.4 0.00092 19.2 0.1 10.9 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME29420.1 - 4.7e-30 103.7 10.1 7.4e-08 32.6 0.3 7.2 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME29420.1 - 1.8e-27 93.2 24.6 0.00022 21.5 0.0 11.8 3 2 10 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 EME29420.1 - 2e-24 84.1 14.1 0.011 15.2 0.0 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME29420.1 - 1.4e-21 76.1 29.3 2.6e-05 24.0 0.1 8.5 3 1 5 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EME29420.1 - 1.8e-18 64.8 5.4 0.78 9.6 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME29420.1 - 5.2e-11 42.2 11.3 0.03 14.7 0.1 9.5 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME29420.1 - 6.8e-11 41.1 16.2 0.56 10.1 0.0 9.3 10 1 1 11 11 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EME29420.1 - 8.3e-08 32.2 5.8 0.028 14.5 0.1 4.3 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EME29420.1 - 5.4e-06 25.6 19.6 0.003 16.6 1.9 4.1 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 EME29420.1 - 4.3e-05 23.2 4.2 9.4 6.1 0.0 7.7 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_5 PF12688.2 EME29420.1 - 0.00037 20.5 0.4 0.036 14.0 0.0 3.3 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_20 PF14561.1 EME29420.1 - 0.00072 19.6 4.1 0.81 9.8 0.1 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EME29420.1 - 0.0012 18.6 6.3 1.7 8.4 0.0 5.7 6 2 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_10 PF13374.1 EME29420.1 - 0.0012 18.7 18.3 2.4 8.2 0.0 7.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 EME29420.1 - 0.0021 18.3 8.8 5 7.8 0.0 6.7 9 0 0 9 9 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME29420.1 - 0.0041 16.9 11.7 2 8.3 0.1 5.6 4 1 0 5 5 5 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EME29420.1 - 0.005 16.0 0.6 0.13 11.4 0.1 3.1 1 1 2 3 3 3 1 Coatomer epsilon subunit HAT PF02184.11 EME29420.1 - 0.012 15.3 4.7 0.21 11.3 0.1 4.4 5 1 0 5 5 4 0 HAT (Half-A-TPR) repeat ChAPs PF09295.5 EME29420.1 - 0.02 13.6 0.2 0.1 11.3 0.0 2.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.7 EME29420.1 - 0.041 13.4 1.6 26 4.3 0.0 4.2 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 EME29420.1 - 0.072 12.9 13.8 6.6 6.6 0.0 7.3 6 3 3 9 9 8 0 MIT (microtubule interacting and transport) domain PPR_3 PF13812.1 EME29420.1 - 0.19 12.0 2.8 36 4.9 0.0 5.1 5 0 0 5 5 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME29420.1 - 0.55 9.7 3.9 14 5.3 0.0 4.7 6 0 0 6 6 5 0 PPR repeat Fis1_TPR_C PF14853.1 EME29420.1 - 1.5 8.7 6.4 6.4 6.7 0.1 4.6 5 1 2 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat DEAD PF00270.24 EME29421.1 - 6.3e-36 123.4 0.0 1.7e-35 121.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME29421.1 - 2.3e-21 75.4 0.0 4.5e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME29421.1 - 1.5e-05 24.9 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME29421.1 - 0.019 15.1 0.2 0.097 12.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 EME29421.1 - 0.093 11.9 0.2 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SPC25 PF06703.6 EME29422.1 - 3.9e-18 65.5 1.0 4.5e-18 65.3 0.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1109 PF06532.6 EME29422.1 - 0.15 11.4 0.2 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) Myb_DNA-binding PF00249.26 EME29423.1 - 5.2e-32 109.6 5.1 3.5e-15 55.7 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME29423.1 - 8.6e-28 96.2 3.4 2.8e-18 65.7 0.1 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EME29423.1 - 0.033 14.0 3.1 4.6 7.1 1.9 3.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2745 PF10922.3 EME29423.1 - 0.036 13.9 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) Myb_DNA-bind_2 PF08914.6 EME29423.1 - 0.045 13.5 0.4 3 7.7 0.1 3.3 2 2 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 EME29423.1 - 5.9 7.0 9.3 19 5.4 0.1 4.0 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Hat1_N PF10394.4 EME29424.1 - 1.6e-16 60.7 0.3 1.6e-16 60.7 0.2 2.2 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Metallophos PF00149.23 EME29424.1 - 5.5e-09 35.7 3.2 1.5e-08 34.3 2.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Acetyltransf_7 PF13508.1 EME29424.1 - 0.013 15.6 0.0 0.07 13.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.16 EME29425.1 - 9.5e-20 70.5 0.0 1.1e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EME29426.1 - 2e-38 131.8 0.0 2.6e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mg_trans_NIPA PF05653.9 EME29427.1 - 3.7e-51 173.8 13.9 4.6e-51 173.5 9.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EME29427.1 - 9.9e-06 25.6 2.5 9.9e-06 25.6 1.8 3.5 2 1 2 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EME29427.1 - 9.7e-05 22.5 19.1 0.00036 20.7 1.0 2.7 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Snf7 PF03357.16 EME29428.1 - 1.8e-35 121.8 14.0 1.8e-35 121.8 9.7 1.3 2 0 0 2 2 2 1 Snf7 Rop-like PF05082.8 EME29428.1 - 0.058 12.8 0.5 0.058 12.8 0.3 2.4 3 0 0 3 3 3 0 Rop-like POR PF01558.13 EME29428.1 - 0.085 12.7 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase MmoB_DmpM PF02406.12 EME29428.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 MmoB/DmpM family Fib_alpha PF08702.5 EME29428.1 - 0.9 9.6 6.0 11 6.1 4.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.13 EME29428.1 - 0.91 8.4 4.8 3.5 6.5 0.7 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CLP_protease PF00574.18 EME29429.1 - 4.4e-80 267.6 0.1 5.8e-80 267.2 0.1 1.1 1 0 0 1 1 1 1 Clp protease GTP_EFTU PF00009.22 EME29430.1 - 2.6e-34 118.3 0.1 2.1e-33 115.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EME29430.1 - 1.2e-20 73.4 0.1 3.6e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EME29430.1 - 7e-12 45.2 14.9 3.8e-10 39.7 0.2 4.5 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EME29430.1 - 1.8e-09 37.1 1.0 1.8e-09 37.1 0.7 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EME29430.1 - 0.00027 20.5 0.1 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RsbRD_N PF14361.1 EME29431.1 - 0.017 15.5 1.9 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF2207 PF09972.4 EME29431.1 - 0.036 12.6 0.6 0.056 12.0 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Arch_ATPase PF01637.13 EME29436.1 - 0.00012 21.9 0.3 0.00046 19.9 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EME29436.1 - 0.01 15.9 0.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EME29437.1 - 0.00064 19.4 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase DUF1504 PF07399.6 EME29438.1 - 0.45 9.1 1.8 0.26 9.8 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1504) SKI PF01202.17 EME29439.1 - 6.6e-37 126.8 0.1 8e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EME29439.1 - 6.8e-09 36.5 0.1 1.1e-08 35.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EME29439.1 - 4.1e-08 33.3 0.6 3.6e-07 30.2 0.5 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 EME29439.1 - 1.3e-06 28.7 1.0 5e-06 26.8 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME29439.1 - 0.0027 17.5 0.0 0.0038 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EME29439.1 - 0.01 15.2 1.1 2.2 7.6 0.1 2.3 1 1 0 2 2 2 0 Thymidylate kinase DUF3298 PF11738.3 EME29439.1 - 0.027 14.9 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) Methyltransf_5 PF01795.14 EME29439.1 - 0.027 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family DUF217 PF02697.9 EME29439.1 - 0.041 14.1 1.9 0.47 10.7 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Pox_RNA_pol PF03293.9 EME29439.1 - 0.056 12.9 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit HTH_40 PF14493.1 EME29439.1 - 0.11 12.7 0.5 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Epimerase PF01370.16 EME29440.1 - 3.3e-11 43.0 0.0 7.3e-10 38.6 0.0 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME29440.1 - 1.5e-10 41.3 0.0 3.3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME29440.1 - 0.0016 17.7 0.0 0.0048 16.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase_Csub PF13950.1 EME29440.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Thioredoxin_4 PF13462.1 EME29441.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF2034 PF10356.4 EME29443.1 - 7.9e-14 51.2 1.9 1e-09 37.8 1.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EME29443.1 - 4.1e-10 39.4 0.0 5.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease CLASP_N PF12348.3 EME29444.1 - 3e-12 46.4 0.1 1.7e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 CLASP N terminal DUF2385 PF09539.5 EME29444.1 - 0.65 10.4 4.4 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) UPF0054 PF02130.12 EME29445.1 - 6e-38 129.3 0.1 7.9e-38 128.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF3634 PF12321.3 EME29445.1 - 0.057 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) DUF1025 PF06262.6 EME29445.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase RLL PF10036.4 EME29446.1 - 6e-27 94.6 0.1 4.2e-26 91.8 0.1 1.9 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein RLL PF10036.4 EME29447.1 - 1.5e-27 96.6 0.1 1.1e-26 93.8 0.0 1.9 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein Helicase_C_2 PF13307.1 EME29448.1 - 4.7e-50 169.8 0.2 9.2e-50 168.8 0.0 1.6 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME29448.1 - 7e-43 146.0 0.7 7e-43 146.0 0.5 2.0 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 EME29448.1 - 0.0021 17.9 0.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sel1 PF08238.7 EME29449.1 - 8.8e-09 35.7 0.3 0.0022 18.5 0.0 4.7 4 1 0 4 4 4 3 Sel1 repeat TB2_DP1_HVA22 PF03134.14 EME29450.1 - 2.3e-32 110.5 2.4 3.3e-32 110.0 1.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family IBV_3C PF03620.8 EME29450.1 - 3.5e-05 23.6 0.2 5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 IBV 3C protein TB2_DP1_HVA22 PF03134.14 EME29451.1 - 2.3e-32 110.5 2.4 3.3e-32 110.0 1.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family IBV_3C PF03620.8 EME29451.1 - 3.5e-05 23.6 0.2 5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 IBV 3C protein RCC1 PF00415.13 EME29452.1 - 4.7e-18 65.1 17.2 7.9e-06 25.9 0.0 6.5 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME29452.1 - 1.8e-10 40.1 20.1 6.3e-05 22.4 0.5 5.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EME29452.1 - 0.0013 19.2 0.2 0.14 12.6 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME29452.1 - 0.0017 18.6 0.0 0.0059 16.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME29452.1 - 0.029 14.1 0.1 7.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 EME29452.1 - 0.1 12.8 0.0 3.1 8.1 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Cytochrom_B558a PF05038.8 EME29452.1 - 0.13 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit SET PF00856.23 EME29453.1 - 7.1e-27 94.6 0.2 2.5e-26 92.9 0.1 2.1 2 0 0 2 2 2 1 SET domain LNS2 PF08235.8 EME29454.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.5 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Aminotran_1_2 PF00155.16 EME29455.1 - 8.3e-48 163.1 0.0 9.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EME29455.1 - 0.00052 18.4 0.0 0.00086 17.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FUN14 PF04930.10 EME29456.1 - 3.2e-18 65.8 1.0 5e-18 65.2 0.1 1.8 2 0 0 2 2 2 1 FUN14 family zf-RING_2 PF13639.1 EME29457.1 - 7.2e-11 41.7 11.0 2.4e-10 40.0 7.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME29457.1 - 6.1e-07 29.3 13.5 1.7e-06 27.9 9.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME29457.1 - 7.8e-07 29.1 7.5 2.3e-06 27.5 5.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger WD40 PF00400.27 EME29457.1 - 1.9e-06 27.5 10.9 0.0081 16.0 0.1 4.5 5 0 0 5 5 4 2 WD domain, G-beta repeat zf-RING_5 PF14634.1 EME29457.1 - 3.2e-06 26.7 11.8 1e-05 25.1 8.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME29457.1 - 6.1e-05 22.6 9.3 6.1e-05 22.6 6.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EME29457.1 - 0.00044 19.5 3.3 0.00076 18.7 2.3 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EME29457.1 - 0.0013 18.3 12.7 0.0039 16.8 8.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME29457.1 - 0.0076 15.9 8.3 0.028 14.1 5.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EME29457.1 - 0.033 14.0 4.0 0.098 12.5 2.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME29457.1 - 0.088 12.4 9.1 0.22 11.1 6.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ADIP PF11559.3 EME29457.1 - 0.11 12.3 4.0 0.21 11.4 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PHD PF00628.24 EME29457.1 - 0.21 11.2 10.3 0.65 9.7 7.1 1.9 1 0 0 1 1 1 0 PHD-finger DUF3496 PF12001.3 EME29457.1 - 0.26 11.5 4.2 0.32 11.2 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) FANCL_C PF11793.3 EME29457.1 - 0.56 10.2 10.4 8.3 6.4 7.0 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_6 PF14835.1 EME29457.1 - 0.64 9.8 8.9 1.8 8.4 4.7 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.16 EME29457.1 - 1.4 8.8 9.9 4.5 7.2 6.9 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 EME29457.1 - 1.7 8.1 6.0 5.1 6.7 4.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EME29457.1 - 2.2 8.1 8.4 85 3.0 5.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 EME29457.1 - 6.7 6.6 16.9 7.5 6.5 8.5 2.9 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.11 EME29457.1 - 9.1 6.2 15.3 9.8 6.1 0.5 2.5 1 1 1 2 2 2 0 FYVE-type zinc finger Pyr_redox_2 PF07992.9 EME29458.1 - 2.8e-22 79.5 0.0 3.9e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME29458.1 - 4.4e-15 55.8 0.3 6.2e-12 45.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME29458.1 - 1.3e-09 38.4 0.0 0.00014 21.9 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME29458.1 - 7e-07 28.4 0.0 0.0031 16.4 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EME29458.1 - 0.00011 21.0 0.0 0.0027 16.3 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EME29458.1 - 0.056 11.9 0.3 3 6.2 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Semialdhyde_dhC PF02774.13 EME29459.1 - 5.5e-35 120.8 0.0 1.1e-34 119.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EME29459.1 - 5.8e-35 120.2 0.0 9.4e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EME29459.1 - 2.2e-05 24.9 0.0 4.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 EME29459.1 - 4.3e-05 24.0 0.0 9.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EME29459.1 - 0.00021 21.1 0.0 0.00043 20.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EME29459.1 - 0.023 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Gp_dh_C PF02800.15 EME29459.1 - 0.082 12.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Mpv17_PMP22 PF04117.7 EME29460.1 - 7.6e-16 57.4 1.0 7.6e-16 57.4 0.7 2.2 2 1 1 3 3 3 1 Mpv17 / PMP22 family ASF1_hist_chap PF04729.8 EME29461.1 - 5.3e-57 191.7 0.1 6.5e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone GCS PF03074.11 EME29462.1 - 4.1e-16 59.0 0.4 1.7e-13 50.3 0.1 2.7 1 1 1 2 2 2 2 Glutamate-cysteine ligase AvrPtoB-E3_ubiq PF09046.5 EME29462.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase Spindle_Spc25 PF08234.7 EME29464.1 - 1.8e-20 72.6 1.4 7.1e-20 70.7 0.4 2.4 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EME29464.1 - 0.0057 15.3 13.6 0.0077 14.9 9.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein CCP_MauG PF03150.9 EME29464.1 - 0.013 15.8 1.5 0.02 15.2 0.8 1.5 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Apc4 PF12896.2 EME29464.1 - 0.037 13.3 6.0 0.2 10.9 1.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 PMC2NT PF08066.7 EME29464.1 - 0.054 13.8 1.2 0.14 12.5 0.7 1.8 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Mnd1 PF03962.10 EME29464.1 - 0.06 12.9 16.8 0.064 12.9 8.0 2.1 1 1 1 2 2 2 0 Mnd1 family Vfa1 PF08432.5 EME29464.1 - 0.094 12.7 7.8 0.17 11.8 5.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3450 PF11932.3 EME29464.1 - 0.11 11.7 12.8 0.064 12.5 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.4 EME29464.1 - 0.13 10.9 14.2 0.19 10.4 9.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cluap1 PF10234.4 EME29464.1 - 0.23 10.6 13.8 0.17 11.0 8.6 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 V_ATPase_I PF01496.14 EME29464.1 - 0.25 9.1 8.5 0.27 9.0 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EME29464.1 - 0.56 9.0 14.2 0.75 8.6 9.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GldM_N PF12081.3 EME29464.1 - 1.1 8.7 11.0 2.1 7.8 7.6 1.5 1 1 0 1 1 1 0 GldM N-terminal domain APG6 PF04111.7 EME29464.1 - 1.2 8.0 17.8 2 7.3 12.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HD_4 PF13328.1 EME29464.1 - 1.3 8.7 5.3 0.62 9.7 1.1 2.1 1 1 1 2 2 2 0 HD domain NPV_P10 PF05531.7 EME29464.1 - 1.8 8.8 5.0 25 5.2 2.2 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EME29464.1 - 2.1 8.0 19.6 0.029 14.0 3.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 EME29464.1 - 2.7 7.6 12.2 3.9 7.1 7.8 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TMPIT PF07851.8 EME29464.1 - 2.9 6.8 8.9 4.2 6.3 6.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.7 EME29464.1 - 2.9 7.6 8.4 2.3 8.0 4.4 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EME29464.1 - 7.1 7.0 14.5 0.79 10.0 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ribonuclease_P PF00825.13 EME29465.1 - 2.5e-05 24.1 0.3 4.2e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease P DnaI_N PF07319.6 EME29466.1 - 0.1 12.8 0.4 0.39 10.9 0.1 2.0 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF1016 PF06250.6 EME29466.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) DUF3353 PF11833.3 EME29467.1 - 5.1e-14 52.1 6.3 4.6e-13 49.0 4.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3353) DnaJ PF00226.26 EME29467.1 - 0.00022 20.9 0.1 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EME29467.1 - 0.095 12.1 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF4131 PF13567.1 EME29467.1 - 1.3 8.3 6.3 8.3 5.7 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3353 PF11833.3 EME29468.1 - 5.1e-14 52.1 6.3 4.6e-13 49.0 4.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3353) DnaJ PF00226.26 EME29468.1 - 0.00022 20.9 0.1 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EME29468.1 - 0.095 12.1 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF4131 PF13567.1 EME29468.1 - 1.3 8.3 6.3 8.3 5.7 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) zf-C3HC4_2 PF13923.1 EME29470.1 - 0.022 14.7 0.2 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME29470.1 - 0.031 13.9 1.1 0.078 12.6 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EME29470.1 - 0.048 13.4 0.6 0.083 12.7 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_60s PF00428.14 EME29471.1 - 2.5e-22 79.0 8.6 3.4e-22 78.6 6.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein IL28A PF15177.1 EME29471.1 - 0.0049 16.4 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Interleukin-28A HTH_38 PF13936.1 EME29471.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain Pribosyltran PF00156.22 EME29472.1 - 2.8e-20 72.2 0.0 5.1e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME29472.1 - 0.0016 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DeoC PF01791.4 EME29472.1 - 0.064 12.5 0.2 8.6 5.5 0.1 2.4 2 0 0 2 2 2 0 DeoC/LacD family aldolase PRTase_2 PF15609.1 EME29472.1 - 0.082 12.1 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Glyco_hydro_35 PF01301.14 EME29473.1 - 7.5e-65 219.3 1.0 9.5e-46 156.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EME29473.1 - 7.1e-11 42.3 0.1 4.9e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.10 EME29473.1 - 3.5e-07 29.6 0.1 7.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.13 EME29473.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_N PF02837.13 EME29473.1 - 0.011 15.3 0.3 0.28 10.7 0.0 3.2 4 0 0 4 4 4 0 Glycosyl hydrolases family 2, sugar binding domain HgmA PF04209.8 EME29474.1 - 2.5e-184 612.6 0.0 2.8e-184 612.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Rav1p_C PF12234.3 EME29475.1 - 1.5e-14 53.0 2.9 2.9e-14 52.1 2.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EME29475.1 - 1e-06 28.3 20.5 0.99 9.3 0.0 8.8 10 0 0 10 10 10 4 WD domain, G-beta repeat efThoc1 PF11957.3 EME29476.1 - 7.2e-61 206.1 15.1 5.4e-60 203.2 10.5 1.9 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Med31 PF05669.7 EME29476.1 - 0.037 13.7 1.4 0.14 11.9 1.0 2.0 1 0 0 1 1 1 0 SOH1 Fe_hyd_SSU PF02256.12 EME29476.1 - 0.041 13.8 1.3 0.07 13.1 0.2 1.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit DUF2389 PF09493.5 EME29476.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.6 3 0 0 3 3 3 0 Tryptophan-rich protein (DUF2389) Cpn60_TCP1 PF00118.19 EME29477.1 - 6.3e-157 523.0 0.3 7.2e-157 522.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TCR PF03638.10 EME29478.1 - 1.5e-26 91.9 55.4 9e-14 51.0 16.6 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain IZUMO PF15005.1 EME29479.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion CTP_transf_3 PF02348.14 EME29481.1 - 6.7e-51 172.9 0.0 8e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.2 EME29481.1 - 9.6e-05 22.5 0.0 0.00024 21.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain TFIIE_alpha PF02002.12 EME29482.1 - 4.9e-14 51.6 3.7 4.9e-14 51.6 2.5 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit NatB_MDM20 PF09797.4 EME29483.1 - 1.9e-32 112.4 7.3 2.4e-32 112.0 4.4 1.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_12 PF13424.1 EME29483.1 - 9.6e-06 25.4 7.2 6e-05 22.9 2.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME29483.1 - 1.7e-05 25.3 3.5 0.001 19.6 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME29483.1 - 8.1e-05 22.9 1.4 0.83 10.4 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EME29483.1 - 0.00025 19.9 0.5 0.00025 19.9 0.3 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EME29483.1 - 0.00029 20.5 13.0 0.00043 19.9 0.5 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME29483.1 - 0.00056 19.7 3.4 0.054 13.4 0.5 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME29483.1 - 0.00066 19.9 11.8 0.049 13.9 0.3 5.2 3 1 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EME29483.1 - 0.00099 19.2 11.3 0.003 17.6 1.8 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EME29483.1 - 0.0023 17.7 0.6 0.0023 17.7 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME29483.1 - 0.0028 17.1 0.8 0.0028 17.1 0.6 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME29483.1 - 0.015 14.9 0.7 0.015 14.9 0.5 3.7 5 0 0 5 5 4 0 TPR repeat TPR_6 PF13174.1 EME29483.1 - 0.031 14.7 6.2 0.97 10.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME29483.1 - 0.076 12.8 10.5 1.1 9.1 0.3 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME29483.1 - 0.12 12.2 10.0 0.039 13.7 0.7 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 EME29485.1 - 5e-16 58.4 0.1 1.9e-09 37.3 0.0 6.2 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.1 EME29485.1 - 1e-14 53.4 3.2 0.011 16.0 0.0 9.0 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.15 EME29485.1 - 7e-14 50.7 12.9 0.043 13.7 0.0 9.5 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.2 EME29485.1 - 0.00038 19.8 1.0 0.92 9.0 0.0 5.0 5 0 0 5 5 5 1 PPR repeat TPR_16 PF13432.1 EME29485.1 - 0.0014 19.2 0.1 0.63 10.7 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME29485.1 - 0.0055 16.4 0.2 39 4.3 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Noelin-1 PF12308.3 EME29485.1 - 0.2 11.4 1.0 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein TPR_1 PF00515.23 EME29485.1 - 0.22 11.1 3.8 69 3.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EME29486.1 - 4.1e-42 143.9 0.0 8.6e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME29486.1 - 1.7e-40 138.2 1.1 2.5e-40 137.7 0.8 1.3 1 0 0 1 1 1 1 DEAD_2 DUF1227 PF06777.6 EME29486.1 - 1.7e-28 99.1 0.0 3.5e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) ResIII PF04851.10 EME29486.1 - 0.0002 21.2 0.2 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EME29486.1 - 0.0012 18.1 0.2 0.021 14.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EME29486.1 - 0.013 15.6 0.9 5.3 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DEAD PF00270.24 EME29486.1 - 0.026 14.0 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 EME29486.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HECT PF00632.20 EME29487.1 - 1.7e-86 290.2 0.0 3.3e-86 289.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT_2 PF13646.1 EME29487.1 - 3e-07 30.6 0.0 0.04 14.2 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats Arm PF00514.18 EME29487.1 - 1.1e-06 28.1 0.2 1.8 8.4 0.0 5.3 4 1 1 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EME29487.1 - 4.9e-05 23.6 0.8 1.2 9.6 0.1 3.9 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EME29487.1 - 0.028 14.5 0.3 31 4.9 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat SRP19 PF01922.12 EME29488.1 - 1.8e-21 76.4 0.0 2.6e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein DUF4031 PF13223.1 EME29488.1 - 0.052 13.6 0.0 0.099 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4031) SRCR PF00530.13 EME29488.1 - 0.08 13.2 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain SRP19 PF01922.12 EME29489.1 - 1.6e-24 86.3 0.0 2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein DUF4031 PF13223.1 EME29489.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4031) SRCR PF00530.13 EME29489.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain UPF0542 PF15086.1 EME29490.1 - 0.66 9.7 0.0 0.66 9.7 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 UL2 PF08196.6 EME29490.1 - 0.97 9.2 4.5 0.55 10.0 1.4 1.9 1 1 0 1 1 1 0 UL2 protein MFS_1 PF07690.11 EME29491.1 - 4.7e-43 147.2 36.7 4.7e-43 147.2 25.4 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EME29491.1 - 0.9 9.6 10.0 0.14 12.2 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2207 PF09972.4 EME29491.1 - 7.7 4.9 8.5 5.6 5.4 1.5 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Brix PF04427.13 EME29492.1 - 1.1e-35 123.1 0.8 1.4e-35 122.7 0.6 1.1 1 0 0 1 1 1 1 Brix domain PDZ PF00595.19 EME29493.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DUF4286 PF14114.1 EME29493.1 - 0.064 13.5 0.2 0.17 12.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4286) DUF4404 PF14357.1 EME29495.1 - 3.9 7.9 6.6 1.8 9.0 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Pro_isomerase PF00160.16 EME29496.1 - 2.5e-47 160.9 0.0 2.8e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cecropin PF00272.14 EME29496.1 - 0.13 11.8 0.8 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Cecropin family Pro_isomerase PF00160.16 EME29497.1 - 2.5e-47 160.9 0.0 2.8e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cecropin PF00272.14 EME29497.1 - 0.13 11.8 0.8 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Cecropin family Smg4_UPF3 PF03467.10 EME29498.1 - 2.7e-10 40.5 0.0 5.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EME29498.1 - 6.4e-05 22.4 0.0 0.05 13.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29498.1 - 0.001 18.9 0.0 0.0036 17.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CoaE PF01121.15 EME29500.1 - 1.4e-55 187.5 0.1 1.7e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EME29500.1 - 3.4e-05 24.6 0.2 6.8e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME29500.1 - 0.00011 22.4 1.5 0.0017 18.6 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME29500.1 - 0.0012 18.6 1.0 0.022 14.6 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME29500.1 - 0.0086 16.0 0.1 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EME29500.1 - 0.031 14.1 0.2 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family Sugar_tr PF00083.19 EME29501.1 - 5e-91 305.5 22.6 7e-91 305.0 15.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29501.1 - 8.1e-29 100.4 23.1 8.1e-29 100.4 16.0 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME29501.1 - 1.1e-08 33.7 3.5 2.6e-08 32.5 0.2 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1761 PF08570.5 EME29501.1 - 0.38 10.7 11.1 0.66 9.9 3.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Asn_synthase PF00733.16 EME29503.1 - 4.2e-65 219.7 0.0 6e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EME29503.1 - 6.4e-31 106.6 0.0 1e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EME29503.1 - 2.8e-21 75.8 0.0 5.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.12 EME29503.1 - 3.2e-05 22.9 0.0 8e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 NAD synthase GATase_2 PF00310.16 EME29503.1 - 0.00096 17.9 0.0 0.063 11.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II DUF3700 PF12481.3 EME29503.1 - 0.0027 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein Sds3 PF08598.6 EME29504.1 - 0.039 13.4 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Sds3-like BAR PF03114.13 EME29505.1 - 0.0012 18.4 11.2 0.0012 18.4 7.7 2.0 1 1 1 2 2 2 1 BAR domain WXG100 PF06013.7 EME29505.1 - 0.029 14.3 3.7 13 5.9 0.0 4.3 3 2 1 4 4 4 0 Proteins of 100 residues with WXG DUF342 PF03961.8 EME29505.1 - 1 7.6 12.3 0.09 11.1 4.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Arfaptin PF06456.8 EME29505.1 - 1.6 8.0 16.3 0.05 12.9 5.9 2.3 2 1 1 3 3 3 0 Arfaptin-like domain GAS PF13851.1 EME29505.1 - 2 7.5 22.8 0.018 14.2 6.9 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding HAUS6_N PF14661.1 EME29505.1 - 2 7.6 14.8 0.051 12.9 3.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Tropomyosin_1 PF12718.2 EME29505.1 - 3.7 7.3 26.9 0.1 12.4 5.4 3.2 3 0 0 3 3 3 0 Tropomyosin like Fib_alpha PF08702.5 EME29505.1 - 5.3 7.1 14.7 0.07 13.2 0.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EME29505.1 - 6.9 5.5 14.2 0.052 12.4 4.0 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_C34 PF05413.6 EME29506.1 - 0.084 12.9 1.1 0.33 11.0 0.1 2.4 2 1 1 3 3 3 0 Putative closterovirus papain-like endopeptidase Peptidase_C34 PF05413.6 EME29507.1 - 0.13 12.3 0.9 0.5 10.4 0.1 2.4 2 1 1 3 3 3 0 Putative closterovirus papain-like endopeptidase SBP56 PF05694.6 EME29508.1 - 1.2e-196 653.7 0.0 1.5e-196 653.4 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EME29508.1 - 0.001 18.2 0.0 0.04 12.9 0.0 3.0 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller LVIVD PF08309.6 EME29508.1 - 0.017 14.1 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 0 LVIVD repeat SGL PF08450.7 EME29508.1 - 0.14 11.5 0.1 11 5.3 0.0 2.9 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region UPF0203 PF05254.7 EME29509.1 - 4.2e-17 61.7 3.7 4.9e-17 61.5 2.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EME29509.1 - 0.0008 19.1 2.3 0.26 11.0 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EME29509.1 - 0.021 14.8 1.3 2.1 8.4 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 EME29509.1 - 0.024 14.5 1.4 3.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EME29509.1 - 0.037 13.9 2.9 0.79 9.7 0.1 2.2 2 0 0 2 2 2 0 CHCH domain PaREP1 PF05942.6 EME29509.1 - 0.06 13.2 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family FTO_CTD PF12934.2 EME29509.1 - 0.082 12.4 0.2 0.082 12.4 0.1 1.1 1 0 0 1 1 1 0 FTO C-terminal domain COX17 PF05051.8 EME29509.1 - 0.094 12.7 1.5 0.8 9.7 1.1 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) HAT PF02184.11 EME29510.1 - 1.4e-22 79.0 64.7 1.1e-07 31.3 0.6 13.0 13 0 0 13 13 13 7 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EME29510.1 - 1.3e-17 63.9 7.3 0.0053 17.0 0.0 7.4 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 EME29510.1 - 5.6e-17 60.7 40.4 0.0076 16.7 0.0 12.4 6 4 7 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 EME29510.1 - 1.9e-14 53.8 27.1 0.0014 19.2 0.1 7.9 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME29510.1 - 2.7e-06 27.2 23.1 0.19 11.7 0.0 7.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EME29510.1 - 1e-05 25.1 16.4 0.17 11.5 0.1 6.4 4 3 3 7 7 7 3 TPR repeat TPR_17 PF13431.1 EME29510.1 - 0.00032 20.6 5.8 0.12 12.6 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EME29510.1 - 0.0014 17.7 24.5 0.03 13.3 5.6 5.1 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME29510.1 - 0.0015 18.1 12.0 30 4.7 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME29510.1 - 0.004 16.9 23.6 32 4.7 0.1 10.1 11 0 0 11 11 11 0 Tetratricopeptide repeat PPR_3 PF13812.1 EME29510.1 - 0.075 13.3 0.3 11 6.6 0.0 4.4 4 0 0 4 4 3 0 Pentatricopeptide repeat domain DUF2225 PF09986.4 EME29510.1 - 0.13 11.7 3.4 0.63 9.4 0.1 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF295 PF03478.13 EME29511.1 - 0.00086 18.6 1.3 1.2 8.5 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF295) Band_7 PF01145.20 EME29513.1 - 2.9e-28 98.9 0.2 4e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EME29513.1 - 0.0054 16.2 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.20 EME29514.1 - 1.5e-32 112.9 0.9 2.2e-32 112.4 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EME29514.1 - 0.0049 16.3 0.1 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 SPFH domain-Band 7 family K_trans PF02705.11 EME29515.1 - 1.9e-156 521.5 36.9 2.4e-156 521.2 25.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter RHIM PF12721.2 EME29516.1 - 2.2 8.7 9.4 42 4.6 4.6 2.7 2 0 0 2 2 2 0 RIP homotypic interaction motif Caprin-1_C PF12287.3 EME29517.1 - 2.5 7.4 13.3 4 6.7 9.2 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term PAT1 PF09770.4 EME29517.1 - 4.3 5.4 4.8 5.5 5.0 3.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YtxC PF08812.6 EME29518.1 - 0.12 11.8 1.5 0.22 10.9 1.0 1.3 1 0 0 1 1 1 0 YtxC-like family E1-E2_ATPase PF00122.15 EME29519.1 - 3.6e-08 32.7 2.6 3.6e-08 32.7 1.8 2.6 2 1 0 2 2 2 1 E1-E2 ATPase ArsB PF02040.10 EME29520.1 - 9e-154 512.4 39.8 1.1e-153 512.1 27.6 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.11 EME29520.1 - 2.4e-16 59.2 31.3 4.8e-16 58.2 21.7 1.5 1 1 0 1 1 1 1 Citrate transporter Aminotran_5 PF00266.14 EME29521.1 - 2e-45 155.1 0.0 2.7e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EME29521.1 - 0.00038 19.5 0.0 0.0096 14.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME29521.1 - 0.0059 15.7 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 EME29521.1 - 0.01 14.3 0.2 0.02 13.3 0.2 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RmlD_sub_bind PF04321.12 EME29521.1 - 0.044 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Prenyltrans PF00432.16 EME29522.1 - 2.3e-62 206.1 9.9 1.5e-12 46.8 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EME29522.1 - 3.4e-31 107.9 0.0 2.1e-17 63.5 0.0 3.3 1 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME29522.1 - 3.6e-15 55.9 0.0 1.2e-05 25.2 0.0 3.4 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 EME29522.1 - 0.0027 16.9 0.1 0.45 9.6 0.0 3.2 3 1 1 4 4 4 1 A-macroglobulin complement component Methyltransf_2 PF00891.13 EME29523.1 - 9.4e-14 51.1 0.0 2.6e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EME29523.1 - 2.2e-11 43.5 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME29523.1 - 3.4e-11 43.4 0.0 6.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29523.1 - 2.6e-10 40.8 0.0 4.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME29523.1 - 3.8e-10 39.3 0.0 6.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EME29523.1 - 3.5e-08 33.7 0.0 9e-08 32.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME29523.1 - 5.8e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29523.1 - 8.2e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME29523.1 - 8.3e-08 31.6 0.0 1.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME29523.1 - 2.5e-06 27.8 0.0 5.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EME29523.1 - 0.0006 19.4 0.1 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) PrmA PF06325.8 EME29523.1 - 0.00064 18.9 0.1 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EME29523.1 - 0.0012 18.2 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 EME29523.1 - 0.0015 17.6 0.0 0.003 16.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 EME29523.1 - 0.0088 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 EME29523.1 - 0.01 15.3 0.1 0.39 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase NodS PF05401.6 EME29523.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) SgrR_N PF12793.2 EME29523.1 - 0.035 14.1 0.1 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term MetW PF07021.7 EME29523.1 - 0.037 13.4 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 EME29523.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1885 PF08968.5 EME29523.1 - 0.041 13.5 1.2 1.2 8.8 0.1 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF1885) DUF4423 PF14394.1 EME29523.1 - 0.084 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Methyltransf_31 PF13847.1 EME29527.1 - 1.8e-27 95.8 0.2 3.2e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME29527.1 - 1.3e-19 70.4 0.0 2.6e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME29527.1 - 1.1e-15 57.3 0.1 9.1e-15 54.4 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME29527.1 - 5.2e-15 55.6 0.1 4.1e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29527.1 - 3.8e-14 52.7 0.0 6.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29527.1 - 1.4e-13 51.4 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME29527.1 - 2.3e-11 44.0 0.0 5.6e-11 42.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME29527.1 - 1.4e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EME29527.1 - 2e-06 27.6 0.1 7.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase PCMT PF01135.14 EME29527.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EME29527.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase HisG PF01634.13 EME29527.1 - 0.0026 17.3 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 ATP phosphoribosyltransferase PrmA PF06325.8 EME29527.1 - 0.0086 15.2 0.0 0.034 13.2 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EME29527.1 - 0.014 13.7 0.0 0.024 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EME29527.1 - 0.026 13.8 0.2 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.13 EME29527.1 - 0.029 13.8 0.0 0.3 10.5 0.0 2.3 3 0 0 3 3 3 0 DNA methylase TehB PF03848.9 EME29527.1 - 0.029 13.5 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB Fibrillarin PF01269.12 EME29527.1 - 0.067 12.0 0.1 0.55 9.1 0.0 2.0 1 1 1 2 2 2 0 Fibrillarin Methyltransf_4 PF02390.12 EME29527.1 - 0.08 11.9 0.0 12 4.9 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 EME29527.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1654 PF07867.6 EME29529.1 - 0.15 11.4 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME29530.1 - 3.3e-05 23.7 0.1 0.00024 20.9 0.0 2.2 2 1 0 2 2 2 1 Archaeal ATPase Citrate_synt PF00285.16 EME29531.1 - 8.7e-98 327.3 0.0 1.1e-97 327.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Tmemb_14 PF03647.8 EME29532.1 - 6.1e-18 65.0 6.9 1.1e-17 64.1 4.7 1.4 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3353 PF11833.3 EME29532.1 - 0.00029 20.3 1.8 0.00059 19.3 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3353) DUF1097 PF06496.6 EME29532.1 - 0.1 12.4 4.2 0.17 11.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) TctB PF07331.6 EME29532.1 - 0.13 11.9 3.3 0.22 11.1 2.3 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Abi PF02517.11 EME29532.1 - 0.42 10.7 5.2 1.6 8.8 3.3 2.2 1 1 1 2 2 2 0 CAAX protease self-immunity DUF4131 PF13567.1 EME29532.1 - 0.51 9.7 6.3 1 8.7 2.5 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) ADH_zinc_N PF00107.21 EME29534.1 - 7.7e-22 77.2 0.1 1.3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME29534.1 - 4.4e-13 50.2 0.2 1.2e-12 48.8 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME29534.1 - 1.2e-11 44.3 0.0 3.7e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF788 PF05620.6 EME29535.1 - 1.1e-30 106.7 3.1 1.2e-30 106.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) YlaC PF10777.4 EME29535.1 - 0.014 14.9 0.1 0.014 14.9 0.1 1.5 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF633 PF04816.7 EME29535.1 - 0.037 13.3 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) DUF788 PF05620.6 EME29536.1 - 1.1e-35 123.0 2.9 1.3e-35 122.7 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) YlaC PF10777.4 EME29536.1 - 0.023 14.2 0.1 0.023 14.2 0.1 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF633 PF04816.7 EME29536.1 - 0.054 12.8 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) Bac_export_2 PF01312.14 EME29536.1 - 0.17 10.7 0.8 0.18 10.6 0.6 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF805 PF05656.9 EME29536.1 - 8.9 6.1 9.3 22 4.8 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF805) ABC2_membrane PF01061.19 EME29537.1 - 1.3e-68 230.3 58.4 1e-35 122.8 15.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EME29537.1 - 1.3e-28 99.9 0.0 7.4e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EME29537.1 - 1.3e-07 31.1 1.2 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EME29537.1 - 1.7e-07 31.2 0.0 5.1e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EME29537.1 - 4.2e-06 26.8 0.1 0.09 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EME29537.1 - 9.4e-06 24.8 0.2 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME29537.1 - 3.1e-05 23.4 0.2 0.029 13.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EME29537.1 - 3.8e-05 22.8 19.0 3.8e-05 22.8 13.2 4.8 2 2 2 4 4 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EME29537.1 - 4.5e-05 22.9 0.8 0.15 11.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EME29537.1 - 8.1e-05 22.9 0.1 0.2 11.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME29537.1 - 9.7e-05 22.5 0.0 0.52 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME29537.1 - 0.00011 22.9 0.3 0.3 11.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EME29537.1 - 0.00014 21.5 0.5 0.53 10.0 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 EME29537.1 - 0.00044 20.1 0.0 0.12 12.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EME29537.1 - 0.001 19.0 0.3 0.11 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME29537.1 - 0.0027 17.1 1.0 0.34 10.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EME29537.1 - 0.0073 15.9 0.3 0.86 9.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EME29537.1 - 0.02 14.3 0.2 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 EME29537.1 - 0.021 14.8 3.8 0.21 11.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA PF00004.24 EME29537.1 - 0.022 14.9 0.1 11 6.2 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EME29537.1 - 0.023 14.6 0.9 6.8 6.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RuvB_N PF05496.7 EME29537.1 - 0.045 12.7 0.4 0.96 8.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EME29537.1 - 0.054 13.6 0.1 12 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 EME29537.1 - 0.1 11.2 0.0 3.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 EME29537.1 - 0.11 11.3 0.8 1.7 7.4 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EME29537.1 - 0.2 11.1 0.1 0.93 8.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EME29537.1 - 0.2 10.4 0.7 20 3.8 0.0 2.7 3 0 0 3 3 3 0 ArgK protein UPF0079 PF02367.12 EME29537.1 - 0.29 10.7 0.6 0.91 9.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EME29537.1 - 0.43 10.1 0.3 4.1 6.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 EME29537.1 - 1 8.9 13.5 3.6 7.1 0.8 3.7 3 0 0 3 3 3 0 Plant PDR ABC transporter associated HTH_9 PF08221.6 EME29539.1 - 2.5e-14 52.8 0.9 6.9e-08 32.2 0.0 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.14 EME29539.1 - 9.1e-05 22.0 0.0 0.39 10.4 0.0 3.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Branch PF02485.16 EME29540.1 - 2.1e-34 118.8 1.4 1.1e-33 116.3 1.0 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme TIM PF00121.13 EME29541.1 - 9.5e-87 290.0 0.0 1.1e-86 289.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase BCAS2 PF05700.6 EME29542.1 - 3.5e-37 128.0 13.1 4.3e-37 127.7 9.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) cIII PF08134.6 EME29542.1 - 0.16 11.5 2.6 2.8 7.5 0.1 2.5 2 0 0 2 2 2 0 cIII protein family DUF1843 PF08898.5 EME29542.1 - 0.58 10.2 2.6 0.51 10.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) AKNA PF12443.3 EME29542.1 - 4.7 7.2 8.6 1.9 8.5 0.7 2.8 2 2 1 3 3 3 0 AT-hook-containing transcription factor MFS_1 PF07690.11 EME29543.1 - 3.2e-14 52.4 28.4 3.2e-14 52.4 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME29543.1 - 2.8e-10 39.2 17.0 2.8e-10 39.2 11.8 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein DUF3392 PF11872.3 EME29543.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3392) AA_permease_C PF13906.1 EME29544.1 - 0.06 13.2 0.2 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 C-terminus of AA_permease YARHG PF13308.1 EME29544.1 - 0.61 9.6 3.5 0.61 9.6 0.9 1.8 2 0 0 2 2 2 0 YARHG domain ABC_tran PF00005.22 EME29545.1 - 6.5e-33 113.9 0.0 1.4e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME29545.1 - 1e-26 93.9 11.4 1e-26 93.9 7.9 2.5 2 1 0 2 2 2 1 ABC transporter transmembrane region Vma12 PF11712.3 EME29545.1 - 1.6e-10 40.8 0.2 6.5e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SMC_N PF02463.14 EME29545.1 - 9.8e-08 31.4 0.3 4e-07 29.4 0.2 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME29545.1 - 2.6e-05 24.3 0.0 0.31 10.9 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME29545.1 - 0.00061 19.8 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME29545.1 - 0.0018 17.4 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME29545.1 - 0.0082 16.9 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME29545.1 - 0.022 14.8 0.1 0.23 11.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME29545.1 - 0.026 14.0 0.1 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME29545.1 - 0.028 14.3 1.1 0.13 12.1 0.1 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EME29545.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EME29545.1 - 0.075 12.4 0.1 0.91 8.9 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain ABC_ATPase PF09818.4 EME29545.1 - 0.16 10.4 1.5 0.13 10.7 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Herpes_LMP1 PF05297.6 EME29545.1 - 2.7 6.8 4.0 5 5.9 2.8 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1049 PF06305.6 EME29545.1 - 5 6.6 7.5 2.4 7.6 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC_tran PF00005.22 EME29546.1 - 5e-33 114.3 0.0 9.5e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME29546.1 - 4.4e-27 95.1 11.4 6e-27 94.7 7.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EME29546.1 - 6.7e-08 32.0 0.4 2.9e-07 29.9 0.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME29546.1 - 1.4e-05 25.2 0.0 0.21 11.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EME29546.1 - 0.00049 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME29546.1 - 0.0013 17.9 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME29546.1 - 0.0065 17.2 0.0 0.014 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME29546.1 - 0.015 15.4 0.1 0.16 12.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME29546.1 - 0.019 14.5 0.1 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME29546.1 - 0.019 14.8 1.3 0.088 12.7 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EME29546.1 - 0.031 14.5 0.0 0.09 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EME29546.1 - 0.088 12.2 0.0 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ABC_ATPase PF09818.4 EME29546.1 - 0.092 11.3 0.1 0.092 11.3 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF87 PF01935.12 EME29546.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Beta-Casp PF10996.3 EME29547.1 - 7.6e-21 74.3 0.5 1.8e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EME29547.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CPSF100_C PF13299.1 EME29547.1 - 1e-07 32.3 0.3 3.5e-06 27.3 0.0 2.9 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.22 EME29547.1 - 1e-07 31.8 0.0 2.8e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EME29547.1 - 1.2e-06 28.2 0.0 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase MBOAT PF03062.14 EME29548.1 - 1e-24 87.2 34.4 2.2e-24 86.1 23.8 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EME29548.1 - 0.00052 20.0 8.1 0.00052 20.0 5.6 2.5 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family Pkinase PF00069.20 EME29549.1 - 6.2e-75 251.6 0.0 7.7e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29549.1 - 5.9e-31 107.4 0.0 8.9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME29549.1 - 4.5e-09 35.6 0.0 8.3e-09 34.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EME29550.1 - 1.3e-68 230.9 0.2 2.4e-36 125.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME29550.1 - 1.4e-25 89.8 0.3 3.8e-13 49.1 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME29550.1 - 7.4e-05 21.8 0.1 0.0021 17.0 0.1 2.3 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.1 EME29550.1 - 0.023 14.2 0.3 0.68 9.4 0.0 2.6 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Polyketide_cyc PF03364.15 EME29551.1 - 3.8e-24 85.1 2.7 1.7e-23 83.0 0.2 2.1 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Alg6_Alg8 PF03155.10 EME29553.1 - 2.1e-101 340.1 27.3 2.7e-101 339.7 18.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Rhodanese PF00581.15 EME29553.1 - 3.5e-07 30.5 0.0 7.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain RRM_1 PF00076.17 EME29554.1 - 4.7e-35 119.0 0.0 2.5e-16 59.0 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29554.1 - 5.2e-24 84.0 0.0 7.4e-11 41.8 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29554.1 - 1.3e-13 50.5 0.1 1e-05 25.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME29554.1 - 0.00081 19.2 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Metallophos PF00149.23 EME29557.1 - 2.1e-09 37.0 1.1 7.7e-09 35.2 0.7 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EME29557.1 - 0.0012 17.5 0.5 0.0021 16.7 0.4 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EME29557.1 - 0.003 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 EME29557.1 - 0.089 12.9 0.2 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Fibronectin type III domain Formyl_trans_N PF00551.14 EME29558.1 - 2e-40 138.2 0.0 2.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Tombus_P19 PF03220.8 EME29558.1 - 0.062 12.6 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Tombusvirus P19 core protein Y2_Tnp PF04986.8 EME29558.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative transposase CutA1 PF03091.10 EME29559.1 - 3.7e-37 126.0 0.3 4.9e-37 125.6 0.2 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein CutA1 PF03091.10 EME29560.1 - 4.8e-37 125.7 0.3 6.6e-37 125.2 0.2 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DKCLD PF08068.7 EME29561.1 - 2.4e-30 104.2 0.3 1.6e-29 101.5 0.1 2.5 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 EME29561.1 - 3.2e-24 85.7 0.2 7.3e-22 78.1 0.1 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EME29561.1 - 5.3e-20 70.9 3.9 1e-19 70.0 2.7 1.5 1 0 0 1 1 1 1 PUA domain BLVR PF06375.6 EME29561.1 - 0.056 13.2 13.4 0.097 12.4 9.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Zip PF02535.17 EME29561.1 - 0.57 9.1 2.4 0.78 8.6 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TIMELESS PF04821.9 EME29561.1 - 0.63 9.2 5.0 29 3.7 0.0 2.2 2 0 0 2 2 2 0 Timeless protein DUF755 PF05501.6 EME29561.1 - 1.5 8.9 23.6 2.8 8.0 16.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_DNAp_acc PF04929.7 EME29561.1 - 2.1 7.1 10.8 3.3 6.5 7.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2103 PF09876.4 EME29562.1 - 1e-16 60.5 0.3 1.9e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2103) Glycos_transf_N PF04413.11 EME29562.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) SP_C-Propep PF08999.5 EME29562.1 - 0.087 12.3 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF935 PF06074.7 EME29563.1 - 0.027 13.1 1.3 0.041 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Lactate_perm PF02652.9 EME29563.1 - 0.12 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lactate permease DUF826 PF05696.6 EME29563.1 - 0.15 12.2 2.0 0.72 10.0 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF826) BLVR PF06375.6 EME29563.1 - 0.21 11.3 10.2 0.091 12.5 5.3 1.7 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Guanylate_kin PF00625.16 EME29564.1 - 1.5e-59 200.4 0.0 1.8e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EME29564.1 - 2.9e-07 30.4 0.0 8.9e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME29564.1 - 1.7e-06 28.8 0.0 3.3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME29564.1 - 1.2e-05 25.6 0.1 3.1e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME29564.1 - 4.3e-05 22.7 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME29564.1 - 9.4e-05 22.4 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EME29564.1 - 0.00038 20.7 0.0 0.00053 20.2 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EME29564.1 - 0.00043 20.4 0.0 0.0015 18.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME29564.1 - 0.0031 16.6 0.0 0.0076 15.3 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.9 EME29564.1 - 0.0046 15.9 0.1 0.023 13.7 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.1 EME29564.1 - 0.0047 16.4 0.1 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EME29564.1 - 0.0064 16.4 0.0 0.0086 16.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.10 EME29564.1 - 0.0069 15.1 0.0 0.0083 14.8 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EME29564.1 - 0.0076 16.5 0.6 0.035 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME29564.1 - 0.0086 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EME29564.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EME29564.1 - 0.016 15.3 0.1 0.058 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase PPK2 PF03976.9 EME29564.1 - 0.02 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_PrkA PF08298.6 EME29564.1 - 0.024 13.3 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_30 PF13604.1 EME29564.1 - 0.024 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EME29564.1 - 0.031 13.5 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EME29564.1 - 0.037 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Miro PF08477.8 EME29564.1 - 0.086 13.3 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 EME29564.1 - 0.095 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EME29564.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 NTPase FbpA PF05833.6 EME29565.1 - 1e-28 100.1 8.1 1e-28 100.1 5.6 2.7 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EME29565.1 - 2.7e-25 88.0 0.2 6.6e-25 86.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 EME29565.1 - 2.2e-24 85.2 0.5 1.8e-23 82.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF1664 PF07889.7 EME29565.1 - 1.5 8.5 9.3 1.1 9.0 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ADH_zinc_N PF00107.21 EME29566.1 - 2.5e-10 40.0 0.0 1e-09 38.0 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME29566.1 - 1.8e-06 27.6 0.1 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME29566.1 - 0.0002 22.2 0.0 0.00037 21.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase COX14 PF14880.1 EME29568.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly COX4 PF02936.9 EME29568.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF1138 PF06592.8 EME29568.1 - 0.26 11.3 1.1 0.32 11.0 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1138) Cpn60_TCP1 PF00118.19 EME29570.1 - 4.6e-139 464.1 13.4 5.3e-139 463.9 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FtsA PF14450.1 EME29570.1 - 1.5 8.6 6.0 1.1 9.1 0.2 3.0 3 1 0 3 3 3 0 Cell division protein FtsA zf-HC5HC2H_2 PF13832.1 EME29571.1 - 4.2e-51 171.5 14.4 1.3e-29 102.3 2.2 4.0 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME29571.1 - 7.5e-37 125.3 10.4 5e-23 81.0 1.3 5.4 5 1 0 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.1 EME29571.1 - 2.8e-11 42.5 3.8 2.8e-11 42.5 2.6 5.9 5 1 0 5 5 5 2 PHD-finger PHD PF00628.24 EME29571.1 - 2.6e-10 39.8 58.2 2e-07 30.6 8.4 6.0 5 1 1 6 6 6 4 PHD-finger C1_1 PF00130.17 EME29571.1 - 1.1 9.0 42.4 0.11 12.1 0.7 5.5 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 EME29572.1 - 4e-73 245.7 0.0 6.1e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29572.1 - 1.7e-32 112.5 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EME29572.1 - 2.8e-07 29.8 0.2 4.6e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME29572.1 - 0.027 14.2 0.3 0.19 11.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EME29572.1 - 0.042 12.8 0.0 1 8.2 0.0 2.2 1 1 0 2 2 2 0 Kinase-like B56 PF01603.15 EME29573.1 - 5.2e-83 278.9 11.2 7.4e-83 278.4 7.8 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF525 PF04379.9 EME29574.1 - 1.9e-22 78.9 0.5 1.5e-21 76.1 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF525) UVR PF02151.14 EME29574.1 - 0.0027 17.1 14.1 0.035 13.6 0.9 2.3 2 0 0 2 2 2 2 UvrB/uvrC motif Arf PF00025.16 EME29575.1 - 1.5e-78 262.0 0.0 1.7e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME29575.1 - 2.8e-14 52.8 0.0 3.3e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EME29575.1 - 1.8e-13 50.0 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EME29575.1 - 8.2e-12 44.5 1.4 1.2e-08 34.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME29575.1 - 4.3e-11 42.3 0.0 5.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME29575.1 - 1.1e-09 38.8 0.0 1.5e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME29575.1 - 7.1e-06 25.9 0.0 1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME29575.1 - 0.0026 17.2 0.0 0.023 14.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EME29575.1 - 0.0035 16.4 0.3 0.0093 15.0 0.2 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EME29575.1 - 0.054 13.3 0.0 0.097 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EME29575.1 - 0.16 11.6 0.4 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sigma70_r3 PF04539.11 EME29576.1 - 9e-05 22.2 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-70 region 3 HTH_17 PF12728.2 EME29576.1 - 0.00068 19.8 0.0 0.39 11.0 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain IF2_N PF04760.10 EME29576.1 - 0.0026 17.3 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region SurA_N PF09312.6 EME29576.1 - 0.0046 16.8 0.0 0.039 13.8 0.0 2.0 1 1 1 2 2 2 1 SurA N-terminal domain Sigma70_r4 PF04545.11 EME29576.1 - 0.02 14.1 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 TRAM_LAG1_CLN8 PF03798.11 EME29577.1 - 2.6e-31 108.7 23.1 3.6e-31 108.2 16.0 1.2 1 0 0 1 1 1 1 TLC domain Epimerase PF01370.16 EME29579.1 - 4.6e-22 78.6 0.0 5.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME29579.1 - 1.3e-20 73.3 0.0 1.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME29579.1 - 1.5e-14 53.5 0.1 2.2e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EME29579.1 - 7.5e-11 41.4 0.1 2.7e-09 36.3 0.2 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EME29579.1 - 1.1e-10 41.7 2.1 1.6e-10 41.1 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EME29579.1 - 5.9e-09 35.2 0.0 1.1e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME29579.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EME29579.1 - 4.4e-06 26.4 0.8 1.1e-05 25.1 0.3 1.9 2 1 0 2 2 2 1 KR domain DapB_N PF01113.15 EME29579.1 - 0.00053 19.8 0.6 0.0012 18.8 0.4 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EME29579.1 - 0.0052 15.8 0.4 0.0073 15.3 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase IMS PF00817.15 EME29580.1 - 1.8e-43 147.8 0.0 4.3e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EME29580.1 - 2.2e-08 34.1 0.0 6.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EME29580.1 - 0.00021 21.1 0.2 0.00082 19.2 0.2 2.1 2 0 0 2 2 2 1 IMS family HHH motif MannoseP_isomer PF01050.13 EME29580.1 - 0.051 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase AhpC-TSA_2 PF13911.1 EME29581.1 - 4.4e-14 52.3 0.0 6.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EME29581.1 - 5.8e-05 22.7 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EME29581.1 - 0.059 13.5 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain polyprenyl_synt PF00348.12 EME29582.1 - 9e-60 201.7 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase CDKN3 PF05706.7 EME29582.1 - 0.015 14.7 0.3 0.46 9.9 0.1 2.9 3 1 1 4 4 4 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF693 PF05113.8 EME29582.1 - 0.033 13.1 0.6 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF693) CLAMP PF14769.1 EME29582.1 - 0.14 12.3 1.2 0.74 9.9 0.0 2.7 2 1 1 3 3 3 0 Flagellar C1a complex subunit C1a-32 Mod_r PF07200.8 EME29583.1 - 3.3e-11 43.3 13.3 4.6e-11 42.8 9.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DNA_topoisoIV PF00521.15 EME29583.1 - 0.28 9.9 10.9 0.47 9.2 5.6 1.9 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A DUF106 PF01956.11 EME29583.1 - 0.4 10.2 1.6 0.64 9.5 1.1 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Clat_adaptor_s PF01217.15 EME29585.1 - 1.7e-11 44.0 1.4 2.2e-11 43.6 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FliT PF05400.8 EME29586.1 - 0.048 14.0 0.2 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 Flagellar protein FliT PDZ_2 PF13180.1 EME29586.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Bud13 PF09736.4 EME29587.1 - 6.7e-33 113.9 6.8 6.7e-33 113.9 4.7 2.5 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex VP4_2 PF08935.5 EME29587.1 - 0.1 13.2 1.5 0.17 12.4 0.2 2.0 2 0 0 2 2 2 0 Viral protein VP4 subunit MIF4G PF02854.14 EME29588.1 - 1.1e-45 155.6 3.6 2.8e-45 154.3 2.5 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EME29588.1 - 3.1e-10 39.7 0.4 2e-08 33.9 0.0 3.0 2 0 0 2 2 2 1 MA3 domain Yip1 PF04893.12 EME29589.1 - 1.6e-09 37.4 15.3 2.1e-09 37.1 10.6 1.2 1 0 0 1 1 1 1 Yip1 domain Maf1 PF09174.5 EME29590.1 - 5.7e-42 143.5 0.4 9.6e-42 142.8 0.3 1.4 1 0 0 1 1 1 1 Maf1 regulator priB_priC PF07445.7 EME29590.1 - 0.03 13.8 0.1 0.072 12.5 0.1 1.7 1 1 0 1 1 1 0 Primosomal replication protein priB and priC Proteasome PF00227.21 EME29591.1 - 2.7e-29 101.8 0.0 3.1e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EcoR124_C PF12008.3 EME29591.1 - 0.14 11.3 0.1 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal OTU PF02338.14 EME29593.1 - 2.1e-18 67.0 0.2 4.3e-18 66.0 0.2 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME29593.1 - 3.6e-07 29.7 2.6 0.0099 15.2 0.0 2.8 1 1 0 3 3 3 2 Peptidase C65 Otubain CTP_transf_1 PF01148.15 EME29594.1 - 2.7e-53 181.2 21.1 3.6e-53 180.8 14.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family RMP PF14996.1 EME29594.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Retinal Maintenance DNA_primase_S PF01896.14 EME29595.1 - 1.7e-43 147.9 0.2 2.7e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit FKBP_C PF00254.23 EME29596.1 - 7.3e-24 83.6 0.0 1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TAT_signal PF10518.4 EME29596.1 - 0.097 12.7 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NIF PF03031.13 EME29598.1 - 3.4e-49 166.5 0.9 5.5e-49 165.8 0.7 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Prp19_bind PF06991.6 EME29599.1 - 7.7e-56 189.3 34.7 7.7e-56 189.3 24.1 2.0 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain PDCD2_C PF04194.8 EME29600.1 - 1.7e-24 86.2 3.3 2.3e-24 85.8 0.8 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Zn_Tnp_IS1595 PF12760.2 EME29600.1 - 0.093 12.5 3.6 2.5 7.9 0.4 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain eIF-6 PF01912.13 EME29601.1 - 2.2e-77 258.6 0.0 2.7e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 eIF-6 family Acetyltransf_1 PF00583.19 EME29603.1 - 1.3e-13 50.7 0.2 1.7e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME29603.1 - 9.2e-07 28.9 0.8 9.8e-07 28.8 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME29603.1 - 6.9e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME29603.1 - 0.0019 18.0 0.4 0.003 17.4 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME29603.1 - 0.0022 17.6 0.1 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 EME29603.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 EME29603.1 - 0.052 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain GDA1_CD39 PF01150.12 EME29604.1 - 4.6e-63 213.2 0.0 5.6e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Neurexophilin PF06312.7 EME29604.1 - 0.098 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Neurexophilin FmdA_AmdA PF03069.10 EME29605.1 - 1.3e-92 310.3 0.0 1.6e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Amino_oxidase PF01593.19 EME29606.1 - 4e-68 230.5 0.0 1.2e-67 228.9 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME29606.1 - 5.7e-10 39.0 0.4 1.2e-09 38.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME29606.1 - 1.2e-05 24.5 0.6 1.9e-05 23.8 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EME29606.1 - 1.6e-05 25.0 0.1 7.2e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME29606.1 - 2.3e-05 23.4 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME29606.1 - 3.1e-05 23.2 0.0 5.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME29606.1 - 9.6e-05 21.3 3.7 0.00014 20.8 2.5 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME29606.1 - 0.00013 20.6 0.8 0.00035 19.1 0.5 1.7 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EME29606.1 - 0.00015 21.6 0.6 0.00025 21.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME29606.1 - 0.00029 19.8 3.2 0.00029 19.8 2.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EME29606.1 - 0.0018 17.3 0.8 0.0033 16.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME29606.1 - 0.0038 17.5 2.5 0.005 17.2 0.9 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME29606.1 - 0.065 12.1 1.5 0.12 11.3 1.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EME29606.1 - 0.47 9.0 3.4 0.35 9.4 1.4 1.4 2 0 0 2 2 2 0 Tryptophan halogenase MAPEG PF01124.13 EME29607.1 - 1.6e-22 79.4 0.2 2e-22 79.1 0.2 1.1 1 0 0 1 1 1 1 MAPEG family HhH-GPD PF00730.20 EME29608.1 - 4.7e-22 78.3 0.0 7.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EME29608.1 - 2.1e-08 33.3 0.0 5e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif FA PF08736.6 EME29608.1 - 0.13 12.0 0.8 0.89 9.4 0.3 2.3 2 0 0 2 2 2 0 FERM adjacent (FA) HhH-GPD PF00730.20 EME29609.1 - 4.7e-22 78.3 0.0 7.7e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EME29609.1 - 2.1e-08 33.3 0.0 5e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif FA PF08736.6 EME29609.1 - 0.13 12.0 0.8 0.89 9.4 0.3 2.3 2 0 0 2 2 2 0 FERM adjacent (FA) GATA PF00320.22 EME29612.1 - 5.2e-10 38.5 5.9 1.3e-09 37.2 4.1 1.8 1 0 0 1 1 1 1 GATA zinc finger Epimerase PF01370.16 EME29613.1 - 2.4e-18 66.4 0.0 3.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.6 EME29613.1 - 7.6e-18 63.7 0.0 1.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_10 PF13460.1 EME29613.1 - 2.3e-08 34.2 0.0 4e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EME29613.1 - 1.7e-05 23.9 0.1 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EME29613.1 - 3.5e-05 22.8 0.2 0.0019 17.1 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EME29613.1 - 5.1e-05 23.1 0.1 9.7e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EME29613.1 - 0.0001 22.6 0.2 0.00035 20.8 0.1 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EME29613.1 - 0.00027 19.7 0.0 0.00051 18.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EME29613.1 - 0.00054 20.0 0.1 0.00092 19.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EME29613.1 - 0.001 18.3 0.0 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EME29613.1 - 0.0014 18.5 0.3 0.017 15.0 0.3 2.1 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EME29613.1 - 0.003 16.5 1.6 0.45 9.3 0.3 2.8 2 1 1 3 3 3 1 Male sterility protein F420_oxidored PF03807.12 EME29613.1 - 0.03 14.7 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EME29613.1 - 0.034 13.0 0.0 0.27 10.1 0.0 2.4 3 0 0 3 3 3 0 RmlD substrate binding domain 3HCDH_N PF02737.13 EME29613.1 - 0.043 13.4 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME29613.1 - 0.071 12.1 0.2 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DapB_N PF01113.15 EME29613.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_N PF03721.9 EME29613.1 - 0.12 11.6 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VWA PF00092.23 EME29614.1 - 5.4e-24 84.8 0.0 8.8e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EME29614.1 - 2e-10 41.0 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain F-box-like PF12937.2 EME29614.1 - 5e-08 32.5 0.3 1.5e-07 31.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like VWA_3 PF13768.1 EME29614.1 - 6.4e-08 32.4 0.1 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain F-box PF00646.28 EME29614.1 - 6.6e-07 28.8 0.9 1.7e-06 27.4 0.6 1.8 1 0 0 1 1 1 1 F-box domain Copine PF07002.11 EME29614.1 - 0.11 12.2 0.1 0.28 10.8 0.1 1.7 1 1 1 2 2 2 0 Copine Chal_sti_synt_C PF02797.10 EME29615.1 - 0.044 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain DUF3728 PF12528.3 EME29615.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.8 2 1 1 3 3 3 0 Prepilin peptidase dependent protein C (DUF3728) Chordopox_A13L PF05961.6 EME29615.1 - 0.19 11.7 1.2 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein FKBP_C PF00254.23 EME29616.1 - 1.6e-22 79.3 0.0 9.5e-22 76.8 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EME29616.1 - 1.8e-13 49.9 5.7 7.2e-09 35.1 0.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EME29616.1 - 2.6e-13 48.7 8.4 0.0006 19.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EME29616.1 - 1.7e-12 46.3 7.8 4.6e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME29616.1 - 8.8e-07 28.6 3.5 3.5e-05 23.5 1.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME29616.1 - 1.9e-05 24.4 7.3 0.00048 20.0 1.9 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME29616.1 - 6.7e-05 23.4 1.5 0.00078 20.0 1.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME29616.1 - 0.00047 19.7 4.7 1.2 9.0 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EME29616.1 - 0.0011 18.8 2.5 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EME29616.1 - 0.0051 16.9 6.0 0.0066 16.5 1.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EME29616.1 - 0.0052 17.3 5.2 0.4 11.4 0.7 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME29616.1 - 0.037 13.8 3.1 0.066 13.0 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME29616.1 - 0.064 13.4 3.8 9.2 6.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME29616.1 - 3.9 7.8 10.3 1.8 8.9 0.4 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat Inositol_P PF00459.20 EME29617.1 - 3.2e-53 180.7 0.0 3.6e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family SE PF08491.5 EME29618.1 - 8.3e-102 339.7 0.0 1.1e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EME29618.1 - 2.4e-18 66.3 0.0 5.9e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME29618.1 - 7.1e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME29618.1 - 0.0002 20.3 2.6 0.0017 17.3 1.3 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME29618.1 - 0.00029 19.8 1.7 0.00029 19.8 1.2 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EME29618.1 - 0.00076 18.6 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EME29618.1 - 0.0021 18.0 0.4 0.0044 17.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME29618.1 - 0.0028 18.0 2.2 0.013 15.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME29618.1 - 0.0035 16.3 0.3 0.0069 15.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GDI PF00996.13 EME29618.1 - 0.0041 15.4 0.0 0.0065 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.17 EME29618.1 - 0.0053 15.6 0.5 0.059 12.2 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EME29618.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EME29618.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EME29618.1 - 0.025 13.0 0.1 0.037 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AvrRpt-cleavage PF05627.6 EME29618.1 - 0.032 13.2 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Shikimate_DH PF01488.15 EME29618.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EME29618.1 - 0.19 10.7 3.0 0.19 10.7 0.8 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_5 PF07994.7 EME29619.1 - 3.8e-99 331.9 0.0 4.4e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EME29619.1 - 1.5e-28 98.8 1.1 3.5e-28 97.6 0.3 2.0 3 0 0 3 3 3 1 Myo-inositol-1-phosphate synthase DHQ_synthase PF01761.15 EME29620.1 - 6.6e-61 205.5 0.0 8.9e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EME29620.1 - 6.1e-13 48.6 0.0 1.4e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EME29620.1 - 0.027 13.1 0.0 0.043 12.4 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase MRP_L53 PF10780.4 EME29621.1 - 6.4e-07 29.2 0.1 1.8e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 FF PF01846.14 EME29621.1 - 0.017 15.0 0.1 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 FF domain CAML PF14963.1 EME29622.1 - 0.063 12.6 3.7 0.09 12.1 2.5 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-CCCH PF00642.19 EME29623.1 - 1.2e-05 24.8 1.7 2.3e-05 23.9 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME29623.1 - 0.093 12.7 2.7 0.2 11.7 1.9 1.6 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_transf_64 PF09258.5 EME29624.1 - 7.3e-55 185.7 0.1 7.3e-55 185.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain 4F5 PF04419.9 EME29624.1 - 5.1e-06 27.1 9.6 5.1e-06 27.1 6.6 2.1 2 0 0 2 2 2 1 4F5 protein family FGase PF05013.7 EME29625.1 - 2.9e-58 197.3 0.0 3.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase FrhB_FdhB_C PF04432.8 EME29627.1 - 3.2e-35 120.8 0.0 6.9e-35 119.8 0.0 1.5 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.8 EME29627.1 - 1.8e-22 79.0 0.0 2.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_17 PF13534.1 EME29627.1 - 0.2 11.9 1.5 0.35 11.2 0.5 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Pkinase PF00069.20 EME29628.1 - 2.1e-79 266.3 0.1 4.3e-79 265.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29628.1 - 2.9e-43 147.8 0.0 5.8e-43 146.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME29628.1 - 1.4e-07 30.7 0.0 1.2e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like KA1 PF02149.14 EME29628.1 - 1.3e-05 24.4 0.2 3.9e-05 22.9 0.2 1.8 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EME29628.1 - 0.0098 14.9 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.6 EME29628.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YukC PF10140.4 EME29628.1 - 0.066 11.7 0.1 0.066 11.7 0.1 1.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EME29628.1 - 0.11 12.2 0.2 0.21 11.2 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family 3Beta_HSD PF01073.14 EME29630.1 - 9.7e-41 139.3 0.1 1.1e-38 132.6 0.0 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME29630.1 - 1.2e-14 54.2 0.0 2.6e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME29630.1 - 4.6e-12 45.3 0.1 2.1e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EME29630.1 - 6.3e-05 22.0 0.2 0.00025 20.0 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME29630.1 - 0.014 14.2 0.0 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EME29631.1 - 1.2e-43 148.8 0.0 2.7e-43 147.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME29631.1 - 1.6e-15 57.1 0.0 2.9e-15 56.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME29631.1 - 4.5e-13 48.7 0.0 2.3e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EME29631.1 - 4.1e-05 22.6 0.1 0.00016 20.7 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME29631.1 - 0.013 14.4 0.0 0.032 13.1 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Metallothio PF00131.15 EME29632.1 - 0.009 15.8 6.6 0.012 15.4 4.6 1.2 1 0 0 1 1 1 1 Metallothionein TOM13 PF08219.6 EME29632.1 - 0.04 13.6 1.2 0.072 12.8 0.8 1.7 1 1 0 1 1 1 0 Outer membrane protein TOM13 Pro_isomerase PF00160.16 EME29633.1 - 7.9e-49 165.8 0.5 8.8e-49 165.6 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA PF00004.24 EME29634.1 - 3.6e-44 150.1 0.0 8.7e-44 148.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EME29634.1 - 4.5e-26 90.5 0.1 7.7e-25 86.5 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EME29634.1 - 2.6e-19 68.8 3.6 1.2e-18 66.7 2.5 2.2 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EME29634.1 - 3.3e-06 27.2 0.5 0.00042 20.4 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EME29634.1 - 3.3e-06 27.9 0.1 1.8e-05 25.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EME29634.1 - 6e-06 25.4 0.0 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EME29634.1 - 1.3e-05 25.2 0.5 0.00046 20.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EME29634.1 - 1.9e-05 24.1 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EME29634.1 - 2.2e-05 24.3 0.0 9.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME29634.1 - 2.4e-05 23.8 0.3 0.21 10.9 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EME29634.1 - 4.7e-05 22.4 0.0 9.1e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EME29634.1 - 8.2e-05 22.3 0.0 0.00035 20.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME29634.1 - 0.00011 22.1 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EME29634.1 - 0.00028 19.7 0.0 0.00072 18.3 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 EME29634.1 - 0.00043 20.1 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EME29634.1 - 0.003 17.2 0.0 0.54 9.8 0.0 2.4 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EME29634.1 - 0.0038 17.3 0.0 0.0095 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EME29634.1 - 0.005 17.1 0.1 0.022 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EME29634.1 - 0.0066 16.0 0.0 0.055 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EME29634.1 - 0.022 14.4 0.3 0.51 10.0 0.0 2.8 2 1 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EME29634.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EME29634.1 - 0.027 13.6 0.0 0.096 11.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EME29634.1 - 0.033 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME29634.1 - 0.034 13.6 0.0 0.2 11.1 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 EME29634.1 - 0.038 13.9 0.9 3.6 7.4 0.0 2.5 2 1 1 3 3 2 0 AAA domain KaiC PF06745.8 EME29634.1 - 0.044 12.9 0.8 6 5.9 0.0 2.8 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EME29634.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Med6 PF04934.9 EME29637.1 - 5.5e-37 126.4 2.5 6.4e-37 126.2 1.3 1.4 1 1 0 1 1 1 1 MED6 mediator sub complex component tRNA-synt_2d PF01409.15 EME29637.1 - 0.065 12.4 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Peptidase_S66 PF02016.10 EME29637.1 - 0.11 11.4 0.1 1.2 8.0 0.1 2.0 1 1 0 1 1 1 0 LD-carboxypeptidase IPK PF03770.11 EME29637.1 - 0.12 11.9 1.2 0.15 11.6 0.8 1.3 1 1 0 1 1 1 0 Inositol polyphosphate kinase Ras PF00071.17 EME29638.1 - 3.7e-51 172.7 0.0 4.7e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME29638.1 - 2.6e-16 60.1 0.0 5.6e-16 59.1 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EME29638.1 - 7e-12 44.9 0.0 9.5e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EME29638.1 - 0.00036 20.6 0.1 0.0037 17.4 0.1 2.3 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EME29638.1 - 0.00042 19.5 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME29638.1 - 0.002 17.5 0.8 0.022 14.1 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EME29638.1 - 0.0044 17.1 0.3 0.12 12.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EME29638.1 - 0.0048 16.8 0.1 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EME29638.1 - 0.0066 15.1 1.3 0.99 8.0 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit ATP_bind_1 PF03029.12 EME29638.1 - 0.025 14.1 0.2 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EME29638.1 - 0.075 12.7 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 NTPase Septin PF00735.13 EME29638.1 - 0.078 11.9 0.1 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Septin SRPRB PF09439.5 EME29638.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EME29638.1 - 0.094 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EME29639.1 - 3.2e-37 128.6 0.1 4.3e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME29639.1 - 7.8e-27 94.3 0.0 1.8e-25 89.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME29639.1 - 4.2e-20 71.9 0.1 1.8e-11 44.0 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EME29639.1 - 7.2e-07 28.9 0.0 0.01 15.4 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase Peptidase_S9 PF00326.16 EME29639.1 - 4.6e-06 26.0 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 EME29639.1 - 2.4e-05 23.8 0.0 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 EME29639.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.15 EME29639.1 - 6.3e-05 22.5 0.1 0.00025 20.5 0.1 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 EME29639.1 - 0.00011 21.7 2.7 0.077 12.4 0.0 3.2 4 0 0 4 4 4 2 Phospholipase/Carboxylesterase Ndr PF03096.9 EME29639.1 - 0.00017 20.1 0.0 0.11 11.0 0.0 2.2 2 0 0 2 2 2 2 Ndr family DUF3530 PF12048.3 EME29639.1 - 0.0015 17.6 0.2 0.055 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) PGAP1 PF07819.8 EME29639.1 - 0.0044 16.6 0.1 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 PGAP1-like protein PhoPQ_related PF10142.4 EME29639.1 - 0.011 14.2 0.0 0.025 13.0 0.0 1.5 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein DUF2048 PF09752.4 EME29639.1 - 0.02 13.8 0.0 0.095 11.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 EME29639.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 EME29639.1 - 0.031 13.9 0.0 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIP PF03583.9 EME29639.1 - 0.051 12.7 0.2 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Secretory lipase DUF2974 PF11187.3 EME29639.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1100 PF06500.6 EME29639.1 - 0.077 11.5 0.1 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.6 EME29639.1 - 0.1 12.3 0.1 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.7 EME29639.1 - 0.13 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DLH PF01738.13 EME29639.1 - 0.14 11.4 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Metallophos PF00149.23 EME29640.1 - 2.6e-08 33.4 0.2 4.7e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME29640.1 - 5.7e-08 32.7 0.0 9.3e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 60KD_IMP PF02096.15 EME29641.1 - 6.5e-60 202.1 0.3 9.9e-60 201.5 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Arginosuc_synth PF00764.14 EME29642.1 - 2.7e-147 490.8 0.0 3.1e-147 490.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EME29642.1 - 0.00026 20.5 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EME29642.1 - 0.002 17.4 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EME29642.1 - 0.011 14.3 0.0 0.017 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase PRP38 PF03371.10 EME29643.1 - 9.9e-17 61.0 0.0 1.1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 PRP38 family HECT PF00632.20 EME29644.1 - 3.2e-93 312.3 0.0 5.3e-93 311.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EME29644.1 - 1.2e-27 95.9 6.3 6.3e-27 93.6 3.1 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4414) DUF1502 PF07397.6 EME29646.1 - 2.9 7.5 6.9 3.5 7.3 2.1 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1502) WD40 PF00400.27 EME29647.1 - 4.5e-10 39.0 0.2 1.2e-06 28.1 0.2 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat vATP-synt_E PF01991.13 EME29648.1 - 1.7e-58 197.1 11.9 1.9e-58 196.9 8.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3535 PF12054.3 EME29648.1 - 0.038 12.6 4.4 0.057 12.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) PC-Esterase PF13839.1 EME29648.1 - 0.058 13.2 0.3 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Plasmid_killer PF05015.8 EME29648.1 - 0.27 11.4 1.5 0.34 11.0 0.3 1.8 2 0 0 2 2 2 0 Plasmid maintenance system killer protein Exonuc_VII_L PF02601.10 EME29648.1 - 0.77 8.8 6.9 1 8.4 4.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.8 EME29648.1 - 7.7 6.9 7.2 4.7 7.6 2.2 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) 2-oxoacid_dh PF00198.18 EME29649.1 - 1.6e-74 250.0 0.1 3.6e-74 248.9 0.0 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME29649.1 - 2.6e-20 71.8 0.4 1.3e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EME29649.1 - 1.8e-17 62.6 0.2 3.6e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EME29649.1 - 2.8e-07 30.0 0.3 0.0048 16.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RRM_1 PF00076.17 EME29650.1 - 1e-08 34.6 0.1 7.9e-08 31.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29650.1 - 2e-08 34.1 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME29650.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EME29650.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cep57_MT_bd PF06657.8 EME29650.1 - 0.09 12.7 1.1 0.26 11.2 0.8 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 MbeB_N PF04837.7 EME29650.1 - 0.35 10.9 6.4 0.24 11.5 1.2 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region LEA_1 PF03760.10 EME29650.1 - 6 7.0 11.3 2.2 8.4 5.4 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 Sigma70_r2 PF04542.9 EME29651.1 - 8.6e-22 76.5 0.3 1.9e-21 75.4 0.2 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.11 EME29651.1 - 1.3e-18 66.6 5.8 4.2e-12 45.7 0.0 4.4 4 1 1 5 5 5 2 Sigma-70 region 3 Sigma70_r4 PF04545.11 EME29651.1 - 1.6e-16 59.3 1.9 6.1e-15 54.2 0.2 3.4 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.15 EME29651.1 - 1.3e-08 34.3 0.0 3.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 Pkinase PF00069.20 EME29653.1 - 1.7e-42 145.3 0.0 3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29653.1 - 9.1e-19 67.5 0.1 4.8e-18 65.1 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME29653.1 - 0.0028 16.6 0.0 0.022 13.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like LIM PF00412.17 EME29654.1 - 6.2e-14 51.8 5.8 9.7e-14 51.1 4.0 1.3 1 0 0 1 1 1 1 LIM domain DUF3133 PF11331.3 EME29654.1 - 0.045 13.3 2.3 0.093 12.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Dicty_REP PF05086.7 EME29654.1 - 0.59 7.8 7.7 0.78 7.4 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cytochrome_C7 PF14522.1 EME29654.1 - 2.8 7.6 7.6 0.13 11.8 1.0 2.0 2 0 0 2 2 2 0 Cytochrome c7 Presenilin PF01080.12 EME29654.1 - 3.7 6.2 5.8 4.7 5.9 4.0 1.1 1 0 0 1 1 1 0 Presenilin TRAPP PF04051.11 EME29655.1 - 1.1e-34 119.1 0.0 1.4e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Arf PF00025.16 EME29656.1 - 2.2e-67 225.6 0.2 2.6e-67 225.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME29656.1 - 2.2e-12 46.6 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME29656.1 - 1.5e-11 44.8 0.0 2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME29656.1 - 2.5e-11 43.1 0.1 3.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EME29656.1 - 3.7e-11 42.5 0.1 4.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EME29656.1 - 2.6e-08 32.9 0.7 1.1e-06 27.6 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EME29656.1 - 6.4e-06 26.1 0.0 8.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME29656.1 - 6.6e-06 25.6 0.1 0.00038 19.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EME29656.1 - 0.0033 17.3 0.0 0.0051 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EME29656.1 - 0.018 14.6 0.5 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.13 EME29656.1 - 0.019 14.2 0.1 0.038 13.2 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B ArgK PF03308.11 EME29656.1 - 0.036 12.8 0.1 0.14 10.9 0.0 2.0 1 1 2 3 3 3 0 ArgK protein Thioredoxin PF00085.15 EME29657.1 - 1.8e-29 101.4 0.0 2.5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME29657.1 - 2.9e-08 33.7 0.0 1.4e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EME29657.1 - 2.7e-07 30.7 0.0 2.5e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME29657.1 - 1.5e-06 28.1 0.1 3.8e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EME29657.1 - 0.00013 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EME29657.1 - 0.00059 19.6 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_6 PF13848.1 EME29657.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 EME29657.1 - 0.03 14.3 2.5 0.052 13.5 0.2 2.4 2 1 0 2 2 2 0 Glutaredoxin AhpC-TSA PF00578.16 EME29657.1 - 0.03 13.9 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family UDPG_MGDP_dh_N PF03721.9 EME29658.1 - 4.9e-30 104.2 0.1 8.5e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EME29658.1 - 8.5e-20 70.7 0.0 1.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EME29658.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME29658.1 - 7e-06 25.8 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EME29658.1 - 0.0013 19.1 0.1 0.057 13.8 0.0 3.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME29658.1 - 0.0014 17.8 0.1 0.013 14.6 0.0 2.5 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EME29658.1 - 0.0088 16.6 0.0 0.24 12.0 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.13 EME29658.1 - 0.0093 15.6 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME29658.1 - 0.036 14.0 0.1 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 EME29658.1 - 0.086 12.2 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EME29659.1 - 6e-30 104.0 0.1 9.3e-30 103.3 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EME29659.1 - 9.2e-20 70.6 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EME29659.1 - 7.9e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME29659.1 - 8.5e-06 25.5 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EME29659.1 - 0.0016 17.5 0.1 0.014 14.5 0.0 2.4 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME29659.1 - 0.0074 16.6 0.1 0.061 13.7 0.0 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EME29659.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EME29659.1 - 0.018 15.6 0.0 0.25 11.9 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain DFP PF04127.10 EME29660.1 - 4e-18 65.7 0.0 3.4e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Vps23_core PF09454.5 EME29660.1 - 0.052 13.1 0.6 4 7.1 0.0 2.7 3 0 0 3 3 3 0 Vps23 core domain Sin_N PF04801.8 EME29661.1 - 3.7e-24 85.3 8.6 3.4e-20 72.2 1.8 3.4 2 2 1 3 3 3 2 Sin-like protein conserved region DUF2551 PF10826.3 EME29661.1 - 0.0072 16.1 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2551) DUF2935 PF11155.3 EME29661.1 - 2.1 8.4 5.9 0.79 9.8 1.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) YCII PF03795.9 EME29662.1 - 2.3e-15 56.5 0.0 4.8e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 YCII-related domain MerB PF03243.10 EME29662.1 - 0.014 15.2 0.1 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alkylmercury lyase RRM_5 PF13893.1 EME29663.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3347 PF11827.3 EME29663.1 - 0.018 15.0 1.4 0.029 14.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) RRM_3 PF08777.6 EME29663.1 - 0.02 14.7 1.0 0.05 13.4 0.0 2.1 2 1 0 2 2 2 0 RNA binding motif DUF4584 PF15223.1 EME29663.1 - 1 8.5 9.2 1.5 7.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) RRM_1 PF00076.17 EME29664.1 - 6.2e-21 73.8 0.0 1.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29664.1 - 8e-16 57.7 0.0 1.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29664.1 - 1.5e-08 34.3 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syd PF07348.7 EME29664.1 - 0.071 12.4 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Syd protein (SUKH-2) Transket_pyr PF02779.19 EME29665.1 - 4.9e-43 146.6 0.0 9.5e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME29665.1 - 1.5e-33 115.3 0.0 7.7e-33 113.0 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Ldh_2 PF02615.9 EME29666.1 - 1.4e-40 139.0 0.1 1.6e-40 138.8 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase RabGAP-TBC PF00566.13 EME29667.1 - 1.5e-26 93.1 7.0 1.5e-26 93.1 4.9 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 EME29667.1 - 3.8e-06 27.2 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain H2TH PF06831.9 EME29668.1 - 8.3e-20 70.3 0.0 1.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EME29668.1 - 2.2e-14 53.8 0.0 4.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain DUF1044 PF06296.7 EME29668.1 - 0.078 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) H2TH PF06831.9 EME29669.1 - 7.2e-20 70.5 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EME29669.1 - 1.7e-09 38.0 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain DUF1044 PF06296.7 EME29669.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) Metallophos PF00149.23 EME29670.1 - 7.6e-28 97.2 0.1 4e-23 81.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Asp_protease PF09668.5 EME29671.1 - 1.3e-52 176.5 0.1 2e-52 175.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 EME29671.1 - 3e-10 39.6 2.3 3.3e-10 39.5 0.0 2.3 3 0 0 3 3 3 1 UBA/TS-N domain Asp_protease_2 PF13650.1 EME29671.1 - 3.9e-09 36.8 0.0 6.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EME29671.1 - 3.7e-07 30.1 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EME29671.1 - 4.3e-07 29.7 0.0 9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EME29671.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 EME29671.1 - 3.7e-05 23.3 0.6 0.012 15.3 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME29671.1 - 0.00044 19.5 0.0 0.00088 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RuvA_C PF07499.8 EME29671.1 - 0.032 14.3 0.6 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 RuvA, C-terminal domain Peptidase_S24 PF00717.18 EME29672.1 - 9.6e-05 21.9 2.8 0.00076 19.0 1.1 2.7 2 1 0 2 2 2 1 Peptidase S24-like Lyase_1 PF00206.15 EME29673.1 - 1.5e-21 76.9 0.0 2.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EME29673.1 - 1.3e-15 57.1 0.1 3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SNF2_N PF00176.18 EME29674.1 - 4.3e-73 245.7 0.1 6.6e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EME29674.1 - 2.2e-22 78.4 2.5 6.1e-14 51.4 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain FYRC PF05965.9 EME29674.1 - 1.3e-19 69.7 0.0 3.8e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 EME29674.1 - 1.5e-17 62.7 0.1 2.9e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus Helicase_C PF00271.26 EME29674.1 - 1.5e-13 50.3 0.1 9.4e-13 47.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME29674.1 - 6.4e-08 32.6 0.0 3.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 EME29674.1 - 0.00087 19.2 4.7 3.8 7.6 0.1 4.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain DEAD PF00270.24 EME29674.1 - 0.0058 16.1 0.0 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME29674.1 - 0.009 16.1 0.0 0.05 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain GST_N_3 PF13417.1 EME29675.1 - 1.7e-14 53.8 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME29675.1 - 2.2e-14 53.3 0.1 5.7e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME29675.1 - 1.9e-13 50.1 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME29675.1 - 3.1e-10 39.9 0.0 5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME29675.1 - 3.8e-09 36.3 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME29675.1 - 7.1e-07 29.6 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EME29675.1 - 0.097 13.0 0.1 0.2 12.0 0.0 1.5 2 0 0 2 2 2 0 MetRS-N binding domain tRNA-synt_2b PF00587.20 EME29676.1 - 1.4e-34 119.1 0.5 5.2e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EME29676.1 - 3.4e-27 94.5 6.9 3.4e-27 94.5 4.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Sigma70_ner PF04546.8 EME29676.1 - 0.0038 16.8 0.6 0.0076 15.8 0.4 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region GAS PF13851.1 EME29676.1 - 0.034 13.3 7.5 0.064 12.4 5.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlgM PF04316.8 EME29676.1 - 0.12 12.3 2.9 8.7 6.3 0.5 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM IncA PF04156.9 EME29676.1 - 0.27 10.7 2.4 0.22 11.0 0.7 1.6 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EME29676.1 - 0.39 10.4 8.5 0.89 9.3 5.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EME29676.1 - 2.7 7.4 10.3 0.4 10.1 4.1 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Pkinase PF00069.20 EME29677.1 - 7.3e-20 71.2 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME29677.1 - 2.8e-14 52.8 0.0 5.6e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Thioredoxin PF00085.15 EME29678.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin BC10 PF06726.7 EME29678.1 - 0.18 11.8 2.5 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 bZIP_2 PF07716.10 EME29679.1 - 7.4e-05 22.4 16.3 0.00024 20.8 10.8 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EME29679.1 - 0.0017 18.3 15.8 0.015 15.2 11.0 2.6 1 1 0 1 1 1 1 bZIP transcription factor Suppressor_APC PF11414.3 EME29679.1 - 0.029 14.1 2.2 0.091 12.5 1.5 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein bZIP_Maf PF03131.12 EME29679.1 - 0.053 13.8 7.7 0.14 12.4 5.4 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor Mto2_bdg PF12808.2 EME29679.1 - 0.1 12.6 8.9 0.28 11.3 5.6 2.2 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IncA PF04156.9 EME29679.1 - 0.56 9.7 8.2 1.3 8.5 5.7 1.9 1 1 0 1 1 1 0 IncA protein FGE-sulfatase PF03781.11 EME29680.1 - 1.1e-28 100.2 0.0 6.8e-27 94.4 0.0 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EME29680.1 - 1.2e-05 25.6 0.5 3.7e-05 24.0 0.4 1.8 1 1 0 1 1 1 1 DinB superfamily Ribosomal_L21e PF01157.13 EME29681.1 - 1.8e-33 114.2 3.0 1.8e-33 114.2 2.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e SOUL PF04832.7 EME29682.1 - 6.2e-41 139.8 1.8 8e-41 139.4 1.3 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein cwf21 PF08312.7 EME29683.1 - 0.077 12.8 0.8 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 cwf21 domain DUF605 PF04652.11 EME29683.1 - 0.19 11.0 10.3 0.21 10.9 7.1 1.2 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EME29683.1 - 5.1 5.2 18.5 6 5.0 12.8 1.2 1 0 0 1 1 1 0 Transmembrane protein PDGF_N PF04692.8 EME29683.1 - 8.1 7.0 9.7 0.25 11.8 1.5 2.4 2 1 0 2 2 2 0 Platelet-derived growth factor, N terminal region DUF1675 PF07897.6 EME29683.1 - 8.5 6.1 19.4 16 5.2 13.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Sod_Fe_C PF02777.13 EME29684.1 - 8.4e-42 141.3 0.1 1.6e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EME29684.1 - 1.6e-28 98.7 0.8 1.6e-28 98.7 0.5 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GAD-like PF08887.6 EME29684.1 - 0.082 12.9 0.0 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 GAD-like domain Methyltransf_8 PF05148.10 EME29685.1 - 1.2e-64 217.9 0.4 1.7e-64 217.4 0.3 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EME29685.1 - 4.7e-09 36.6 0.0 9.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29685.1 - 1.1e-05 25.1 0.2 0.00027 20.5 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29685.1 - 0.00028 20.6 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29685.1 - 0.0015 19.1 0.0 0.0032 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME29685.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME29685.1 - 0.037 14.5 0.0 0.12 12.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME29685.1 - 0.054 12.8 0.1 2.3 7.5 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase small domain Dppa2_A PF14049.1 EME29685.1 - 0.061 13.1 1.1 0.18 11.6 0.7 1.8 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Methyltransf_32 PF13679.1 EME29685.1 - 0.098 12.3 0.0 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain AalphaY_MDB PF04611.7 EME29685.1 - 0.13 12.0 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Archease PF01951.11 EME29685.1 - 0.14 12.0 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) Fip1 PF05182.8 EME29686.1 - 3.1e-22 77.5 0.9 8e-22 76.2 0.7 1.7 1 0 0 1 1 1 1 Fip1 motif p25-alpha PF05517.7 EME29688.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 p25-alpha AvrL567-A PF11529.3 EME29688.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A DUF4341 PF14241.1 EME29689.1 - 2.5e-12 46.2 8.9 2.5e-12 46.2 6.2 3.8 5 1 1 6 6 6 1 Domain of unknown function (DUF4341) Sulf_transp PF04143.9 EME29689.1 - 0.016 15.2 3.3 0.016 15.2 2.3 4.8 5 0 0 5 5 5 0 Sulphur transport PHD PF00628.24 EME29690.1 - 9.3e-13 47.6 11.0 2.5e-12 46.2 7.6 1.8 1 0 0 1 1 1 1 PHD-finger INCENP_ARK-bind PF03941.10 EME29690.1 - 1.8e-12 46.9 0.1 1.8e-12 46.9 0.0 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PHD_2 PF13831.1 EME29690.1 - 0.016 14.4 2.5 0.04 13.2 1.7 1.7 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 EME29691.1 - 9.3e-13 47.6 11.0 2.5e-12 46.2 7.6 1.8 1 0 0 1 1 1 1 PHD-finger INCENP_ARK-bind PF03941.10 EME29691.1 - 1.8e-12 46.9 0.1 1.8e-12 46.9 0.0 2.7 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PHD_2 PF13831.1 EME29691.1 - 0.016 14.4 2.5 0.04 13.2 1.7 1.7 1 0 0 1 1 1 0 PHD-finger Nrap PF03813.9 EME29692.1 - 3.6e-73 246.6 3.3 3.4e-65 220.2 0.1 2.5 2 1 0 2 2 2 2 Nrap protein Shugoshin_N PF07558.6 EME29693.1 - 0.021 14.5 3.7 0.054 13.2 1.8 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1423 PF07227.6 EME29693.1 - 0.036 12.7 2.1 0.042 12.5 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1423) DUF972 PF06156.8 EME29693.1 - 0.047 14.0 8.8 4.7 7.6 4.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) RTTN_N PF14726.1 EME29693.1 - 0.082 13.4 1.0 0.89 10.1 0.0 2.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Imm42 PF15601.1 EME29693.1 - 0.11 11.8 1.4 0.27 10.6 0.9 1.7 1 1 0 1 1 1 0 Immunity protein 42 Baculo_p24 PF05073.7 EME29693.1 - 0.14 11.6 4.7 0.19 11.2 3.3 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein FUSC PF04632.7 EME29693.1 - 0.22 9.8 2.4 0.3 9.4 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.11 EME29693.1 - 0.25 9.8 1.7 0.27 9.7 1.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FadA PF09403.5 EME29693.1 - 0.39 10.7 7.1 0.38 10.7 3.5 1.9 1 1 1 2 2 2 0 Adhesion protein FadA Vps51 PF08700.6 EME29693.1 - 0.84 9.5 6.6 0.32 10.8 1.5 2.3 2 1 1 3 3 3 0 Vps51/Vps67 Exonuc_VII_L PF02601.10 EME29693.1 - 1.3 8.1 7.6 1.5 7.9 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBPIP PF07106.8 EME29693.1 - 2.3 7.7 12.5 1.6 8.2 3.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIVA PF05103.8 EME29693.1 - 2.5 8.1 9.2 6 6.9 6.1 1.8 1 1 0 1 1 1 0 DivIVA protein TPR_MLP1_2 PF07926.7 EME29693.1 - 3 7.5 14.8 1.5 8.5 7.9 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 EME29693.1 - 5.6 6.2 15.2 4.1 6.7 8.7 1.8 1 1 1 2 2 2 0 PspA/IM30 family TMPIT PF07851.8 EME29693.1 - 7.6 5.5 10.2 1.3 8.0 0.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein Glycolytic PF00274.14 EME29694.1 - 1.8e-119 398.2 0.0 2e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I TFR_dimer PF04253.10 EME29694.1 - 0.027 14.0 0.0 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain AP_endonuc_2 PF01261.19 EME29695.1 - 1.3e-25 89.9 0.0 1.7e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 EME29695.1 - 0.0058 16.1 0.0 0.042 13.3 0.0 2.2 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus Alg6_Alg8 PF03155.10 EME29696.1 - 1.3e-25 90.1 5.2 1.6e-25 89.9 3.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ndc80_HEC PF03801.8 EME29696.1 - 0.092 12.1 1.1 0.12 11.7 0.8 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family Alg6_Alg8 PF03155.10 EME29697.1 - 4.4e-37 128.0 22.7 1.3e-24 86.8 3.0 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Metallophos PF00149.23 EME29698.1 - 2e-07 30.6 3.8 1.2e-06 28.1 2.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME29698.1 - 1.1e-05 25.2 2.5 2.5e-05 24.1 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NRN1 PF15056.1 EME29698.1 - 0.00059 19.7 0.2 0.012 15.5 0.0 2.7 3 0 0 3 3 3 1 Neuritin protein family Tox-ART-HYE1 PF15634.1 EME29698.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Ribosomal_S3_C PF00189.15 EME29699.1 - 0.00011 22.3 0.0 0.00034 20.7 0.0 1.8 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain PapD-like PF14874.1 EME29700.1 - 0.058 13.3 0.0 30 4.6 0.0 3.7 3 0 0 3 3 3 0 Flagellar-associated PapD-like XPG_N PF00752.12 EME29701.1 - 6.3e-30 103.4 0.0 1.2e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EME29701.1 - 2.9e-28 97.7 1.2 3.8e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EME29701.1 - 0.00034 20.7 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Sigma70_r1_1 PF03979.9 EME29701.1 - 0.097 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 MMR_HSR1 PF01926.18 EME29702.1 - 2.1e-12 47.0 0.0 3.1e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EME29702.1 - 0.0009 18.4 0.1 0.0034 16.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EME29702.1 - 0.0016 18.1 0.1 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EME29702.1 - 0.0039 17.0 0.2 0.11 12.3 0.0 2.7 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EME29702.1 - 0.0049 17.3 0.6 0.059 13.8 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EME29702.1 - 0.027 13.7 0.2 0.53 9.5 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EME29702.1 - 0.027 14.0 0.5 2 7.8 0.1 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EME29702.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EME29702.1 - 0.11 11.9 0.0 6.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DHDPS PF00701.17 EME29703.1 - 5.5e-95 317.2 0.0 6.4e-95 317.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF521 PF04412.8 EME29703.1 - 0.063 11.8 0.3 0.088 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF1997 PF09366.5 EME29704.1 - 5.5e-23 81.4 0.0 7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF1215 PF06744.7 EME29704.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) DnaJ PF00226.26 EME29705.1 - 6e-30 102.7 3.7 1.1e-29 101.9 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME29705.1 - 6.2e-26 90.1 3.4 3e-23 81.4 0.6 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Aminotran_4 PF01063.14 EME29706.1 - 3.6e-13 49.5 0.1 7.2e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 EME29707.1 - 2.2e-32 112.1 39.8 1.5e-28 99.5 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p53-inducible11 PF14936.1 EME29707.1 - 7.4 6.4 8.1 15 5.4 0.1 2.4 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF2304 PF10066.4 EME29707.1 - 8.3 6.3 12.2 5.7 6.8 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF3007 PF11460.3 EME29708.1 - 3.8e-21 75.1 0.2 5.1e-21 74.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) Oleosin PF01277.12 EME29708.1 - 0.044 13.3 0.1 0.085 12.4 0.0 1.4 1 1 0 1 1 1 0 Oleosin RTC PF01137.16 EME29710.1 - 1.3e-37 128.8 0.0 1.5e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EME29710.1 - 1.6e-12 47.3 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Glyco_hydro_14 PF01373.12 EME29711.1 - 5.5e-97 325.0 0.7 6.9e-97 324.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Trehalase PF01204.13 EME29713.1 - 2.5e-121 405.8 0.1 2.9e-121 405.6 0.1 1.0 1 0 0 1 1 1 1 Trehalase VAD1-2 PF15310.1 EME29713.1 - 0.37 10.4 1.7 0.55 9.8 1.2 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Tic20 PF09685.5 EME29714.1 - 0.014 15.3 9.0 0.026 14.4 6.2 1.6 1 1 0 1 1 1 0 Tic20-like protein RPE65 PF03055.10 EME29716.1 - 7.7e-95 318.2 0.0 1e-94 317.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein tRNA-synt_2 PF00152.15 EME29716.1 - 2.9e-71 239.9 0.0 5.4e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) RPE65 PF03055.10 EME29717.1 - 1.8e-72 244.4 0.0 2.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cullin PF00888.17 EME29718.1 - 8.3e-138 460.5 11.2 1.1e-137 460.1 7.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME29718.1 - 1.7e-27 95.0 3.3 6e-27 93.2 2.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Gal-bind_lectin PF00337.17 EME29718.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Galactoside-binding lectin Cullin PF00888.17 EME29719.1 - 7e-137 457.4 10.4 1e-136 456.9 7.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME29719.1 - 1.8e-27 94.9 3.3 6.2e-27 93.2 2.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Gal-bind_lectin PF00337.17 EME29719.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Galactoside-binding lectin UCH PF00443.24 EME29720.1 - 1.1e-66 224.7 1.3 1.5e-66 224.2 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME29720.1 - 1.7e-32 113.0 4.6 1.1e-24 87.4 0.8 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TPR_11 PF13414.1 EME29721.1 - 0.00025 20.6 1.1 0.14 11.7 0.2 2.7 1 1 1 2 2 2 2 TPR repeat TPR_11 PF13414.1 EME29722.1 - 0.00025 20.6 1.1 0.14 11.7 0.2 2.7 1 1 1 2 2 2 2 TPR repeat GntR PF00392.16 EME29724.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family ABC_membrane_2 PF06472.10 EME29725.1 - 4.3e-37 127.7 9.1 5.8e-37 127.3 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME29725.1 - 2.2e-17 63.6 0.0 3.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME29725.1 - 0.0015 18.5 0.1 0.94 9.3 0.0 3.0 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EME29725.1 - 0.0028 17.6 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME29725.1 - 0.0074 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EME29725.1 - 0.0082 15.5 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EME29725.1 - 0.019 15.0 0.0 0.078 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME29725.1 - 0.037 13.1 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 EME29725.1 - 0.058 12.0 0.1 0.099 11.3 0.1 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EME29725.1 - 0.08 12.4 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EME29725.1 - 0.2 11.0 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family SDA1 PF05285.7 EME29726.1 - 2.9e-27 95.7 39.9 1.8e-17 63.6 0.9 3.9 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.7 EME29726.1 - 0.00035 20.7 0.2 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 1 NUC130/3NT domain DND1_DSRM PF14709.1 EME29726.1 - 0.03 14.6 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_1 PF00076.17 EME29727.1 - 6.9e-19 67.2 0.0 1.5e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29727.1 - 1.3e-15 57.0 0.0 2.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29727.1 - 6.2e-11 41.9 0.1 1e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomyosin_1 PF12718.2 EME29727.1 - 0.016 15.0 6.3 0.023 14.5 4.3 1.2 1 0 0 1 1 1 0 Tropomyosin like Nup35_RRM_2 PF14605.1 EME29727.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Bap31 PF05529.7 EME29727.1 - 5.3 6.4 5.2 7.3 6.0 3.6 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TFIID-31kDa PF02291.10 EME29728.1 - 2.2e-37 127.7 0.1 2.7e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EME29728.1 - 6e-07 29.5 0.1 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EME29728.1 - 1.9e-05 24.2 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EME29728.1 - 0.0021 18.1 0.1 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EME29728.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF4158 PF13700.1 EME29728.1 - 0.1 12.0 0.0 0.7 9.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4158) HSF_DNA-bind PF00447.12 EME29730.1 - 4.7e-30 103.8 0.1 1.9e-29 101.8 0.1 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding AHSP PF09236.5 EME29730.1 - 0.058 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein DEAD PF00270.24 EME29731.1 - 3.5e-23 81.9 0.0 1e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DSHCT PF08148.7 EME29731.1 - 4.1e-20 71.7 0.0 4.1e-20 71.7 0.0 3.0 2 1 1 3 3 3 1 DSHCT (NUC185) domain ResIII PF04851.10 EME29731.1 - 5.3e-08 32.9 0.7 1.4e-06 28.3 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME29731.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.12 EME29731.1 - 5.3e-05 22.7 0.0 0.00021 20.7 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME29731.1 - 0.00011 21.8 0.2 0.00042 19.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EME29731.1 - 0.00014 22.2 6.2 0.08 13.2 0.4 3.4 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 EME29731.1 - 0.00015 20.7 0.0 0.00029 19.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EME29731.1 - 0.0041 16.7 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EME29731.1 - 0.0053 16.0 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_10 PF12846.2 EME29731.1 - 0.016 14.6 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATG19_autophagy PF12744.2 EME29731.1 - 0.038 13.2 2.2 0.077 12.2 1.5 1.5 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding AAA_29 PF13555.1 EME29731.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EME29731.1 - 0.11 11.8 0.0 0.11 11.8 0.0 3.1 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain Ribosomal_L1 PF00687.16 EME29732.1 - 2.6e-50 170.7 6.6 3.1e-50 170.5 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF647 PF04884.9 EME29732.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ribosomal_L31e PF01198.14 EME29733.1 - 1.5e-36 123.9 0.9 1.8e-36 123.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ldh_1_N PF00056.18 EME29734.1 - 2.1e-24 85.9 0.1 2.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EME29735.1 - 3.3e-38 131.1 0.0 3.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Met_synt_B12 PF02965.12 EME29735.1 - 0.048 12.8 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain IlvN PF07991.7 EME29735.1 - 0.052 12.9 0.1 6.2 6.1 0.0 2.3 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Methyltransf_11 PF08241.7 EME29736.1 - 1.1e-19 70.6 0.0 1.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME29736.1 - 1.9e-18 66.4 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EME29736.1 - 3.1e-13 49.7 0.0 4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29736.1 - 2.4e-10 40.2 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME29736.1 - 3.2e-10 40.2 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29736.1 - 6.3e-10 39.6 0.0 8.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME29736.1 - 3.4e-09 37.0 0.0 6.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME29736.1 - 0.00066 19.7 0.0 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EME29736.1 - 0.0057 16.0 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EME29736.1 - 0.05 13.2 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase UPF0020 PF01170.13 EME29736.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MutS_V PF00488.16 EME29737.1 - 9.3e-87 290.3 0.0 1.4e-86 289.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME29737.1 - 1.7e-34 119.3 2.1 3.8e-33 115.0 2.3 2.5 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EME29737.1 - 1.9e-12 47.1 0.2 5.9e-12 45.5 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV DHBP_synthase PF00926.14 EME29738.1 - 1e-82 276.0 0.0 1.5e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.15 EME29738.1 - 3.6e-69 231.3 0.0 6.1e-69 230.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Actin PF00022.14 EME29739.1 - 3.8e-67 226.4 0.0 7.8e-67 225.4 0.0 1.4 1 1 0 1 1 1 1 Actin zf-C2H2_7 PF15269.1 EME29739.1 - 0.5 10.2 2.3 1 9.2 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger Topoisom_bac PF01131.15 EME29741.1 - 7.3e-88 295.0 0.0 8.8e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EME29741.1 - 2.2e-14 53.2 0.0 4.5e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain TryThrA_C PF12319.3 EME29741.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal UNC-50 PF05216.8 EME29742.1 - 7.9e-66 221.5 18.9 9.4e-66 221.3 13.1 1.0 1 0 0 1 1 1 1 UNC-50 family FAM165 PF14981.1 EME29742.1 - 0.032 13.7 3.2 0.088 12.3 0.1 2.8 3 0 0 3 3 3 0 FAM165 family UNC-50 PF05216.8 EME29743.1 - 4.3e-66 222.4 19.4 5.1e-66 222.2 13.4 1.0 1 0 0 1 1 1 1 UNC-50 family FAM165 PF14981.1 EME29743.1 - 0.034 13.6 3.2 0.091 12.2 0.1 2.8 3 0 0 3 3 3 0 FAM165 family LRR_4 PF12799.2 EME29744.1 - 5e-13 48.3 7.1 6.7e-08 31.9 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EME29744.1 - 8.3e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EME29744.1 - 2e-08 33.8 5.5 7.1e-05 22.4 0.2 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EME29744.1 - 0.00055 19.6 6.6 3.3 8.2 0.0 4.7 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EME29744.1 - 0.0073 16.1 5.5 0.94 9.7 0.0 4.0 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 EME29744.1 - 0.022 14.7 6.4 1.8 8.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Chloroa_b-bind PF00504.16 EME29745.1 - 6.7e-39 133.6 0.0 8.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Skp1 PF01466.14 EME29746.1 - 8.2e-40 134.7 0.6 1.7e-39 133.7 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EME29746.1 - 1.2e-22 79.7 0.4 1.9e-22 79.1 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain G-patch PF01585.18 EME29747.1 - 1.3e-11 44.0 1.3 2.4e-11 43.2 0.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EME29747.1 - 6.7e-07 29.0 0.1 6.7e-07 29.0 0.1 2.6 2 1 0 2 2 2 1 DExH-box splicing factor binding site DUF3405 PF11885.3 EME29747.1 - 0.061 11.5 2.7 0.069 11.3 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) LANC_like PF05147.8 EME29748.1 - 4.8e-68 229.3 0.2 6.4e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein RWP-RK PF02042.10 EME29750.1 - 5.4e-17 61.3 0.1 9.8e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Peptidase_S9 PF00326.16 EME29751.1 - 7.2e-34 116.8 0.0 1.2e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME29751.1 - 3.4e-11 43.0 0.0 9.1e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EME29751.1 - 6.9e-09 35.5 0.3 2.6e-06 27.0 0.4 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EME29751.1 - 1.2e-08 35.1 0.0 2.6e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME29751.1 - 3.1e-06 26.6 0.0 2.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EME29751.1 - 0.0015 18.3 0.0 0.0057 16.3 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EME29751.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Arch_ATPase PF01637.13 EME29752.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Arch_ATPase PF01637.13 EME29754.1 - 0.05 13.2 0.1 0.24 11.0 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase WD40 PF00400.27 EME29762.1 - 2.9e-35 118.8 3.0 4.3e-12 45.4 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ATP-synt_10 PF05176.9 EME29762.1 - 0.0011 18.2 0.2 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 ATP10 protein Nup160 PF11715.3 EME29762.1 - 0.003 15.7 0.0 0.069 11.2 0.0 2.6 1 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40 PF00400.27 EME29763.1 - 2.4e-19 68.3 9.1 3.3e-07 29.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EME29763.1 - 1.5e-13 50.3 0.0 4.3e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Tyr_Deacylase PF02580.11 EME29764.1 - 5.5e-40 136.6 0.0 6.2e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FAD_binding_7 PF03441.9 EME29765.1 - 2e-98 329.0 0.7 2.5e-98 328.6 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME29765.1 - 1.9e-38 131.8 0.0 4.8e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase Pterin_4a PF01329.14 EME29766.1 - 5.3e-28 96.6 0.0 6.7e-28 96.3 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NIR_SIR PF01077.17 EME29767.1 - 2.6e-56 189.3 0.0 1.4e-42 144.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EME29767.1 - 5.7e-24 83.5 0.1 5.2e-14 51.6 0.0 3.2 4 0 0 4 4 4 2 Nitrite/Sulfite reductase ferredoxin-like half domain WD40 PF00400.27 EME29768.1 - 4.8e-38 127.7 21.2 2.1e-10 40.0 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat VCBS PF13517.1 EME29768.1 - 0.025 14.9 0.6 67 3.9 0.0 4.1 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4613 PF15390.1 EME29768.1 - 0.029 12.5 0.3 0.042 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Acetyltransf_1 PF00583.19 EME29769.1 - 1.1e-17 63.8 0.0 2.5e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME29769.1 - 3.7e-09 36.6 0.0 9.3e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME29769.1 - 3.4e-08 33.1 0.0 8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EME29769.1 - 1.2e-07 31.6 0.3 1.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME29769.1 - 4.7e-07 30.0 0.0 7.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME29769.1 - 8.1e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME29769.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME29769.1 - 0.004 17.0 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EME29769.1 - 0.011 15.3 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EME29769.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase NIF PF03031.13 EME29770.1 - 4.8e-49 166.0 1.0 2.1e-48 163.9 0.5 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase NIF PF03031.13 EME29771.1 - 5e-49 166.0 1.0 2.2e-48 163.9 0.5 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase eIF-5_eIF-2B PF01873.12 EME29772.1 - 2.4e-41 140.2 0.0 3.7e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EME29772.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar PGA2 PF07543.7 EME29772.1 - 0.19 11.5 6.0 0.3 10.8 4.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 NST1 PF13945.1 EME29772.1 - 0.4 10.7 5.6 3.2 7.8 1.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator EamA PF00892.15 EME29773.1 - 0.00017 21.6 14.2 0.00045 20.2 6.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EME29773.1 - 0.00074 18.5 6.1 0.0011 18.0 4.2 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EME29773.1 - 0.045 13.3 0.2 0.045 13.3 0.1 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 EME29773.1 - 0.51 10.5 11.9 0.12 12.6 4.6 2.2 2 1 0 2 2 2 0 Multidrug resistance efflux transporter TPT PF03151.11 EME29774.1 - 1.2e-13 50.9 9.6 1.2e-13 50.9 6.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME29774.1 - 0.0001 22.3 28.8 0.001 19.1 7.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EME29774.1 - 0.00049 19.1 20.9 0.00082 18.3 14.5 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EME29774.1 - 0.18 12.0 22.9 0.21 11.7 4.7 2.4 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF3067 PF11267.3 EME29775.1 - 2.5e-28 98.0 0.3 3.6e-28 97.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3067) Nop14 PF04147.7 EME29776.1 - 1.3e-19 69.6 9.4 1.8e-11 42.7 0.1 3.3 2 1 2 4 4 4 2 Nop14-like family WD40 PF00400.27 EME29777.1 - 1.3e-24 85.1 4.8 2e-07 30.6 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Prefoldin PF02996.12 EME29777.1 - 0.032 13.8 1.1 0.15 11.6 0.9 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF3552 PF12072.3 EME29777.1 - 0.047 12.8 8.8 0.072 12.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1043 PF06295.7 EME29777.1 - 0.075 12.6 0.9 0.16 11.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.14 EME29777.1 - 2.1 6.0 6.9 0.59 7.9 3.0 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GcpE PF04551.9 EME29778.1 - 2.5e-142 473.9 0.1 2.8e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 GcpE protein Proteasome PF00227.21 EME29780.1 - 4.9e-59 198.8 0.1 6e-59 198.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME29780.1 - 9.9e-15 53.5 0.2 1.7e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SIR2 PF02146.12 EME29781.1 - 2.2e-32 112.2 0.0 3.2e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EME29781.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain GYF PF02213.11 EME29782.1 - 6.5e-06 25.6 0.4 1.5e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 GYF domain DUF3069 PF11269.3 EME29782.1 - 0.0096 16.0 0.3 0.024 14.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3069) DUF4339 PF14237.1 EME29782.1 - 0.02 14.4 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) T2SF PF00482.18 EME29782.1 - 0.077 12.8 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F SnoaL_3 PF13474.1 EME29783.1 - 2.7e-20 72.5 1.0 3.7e-20 72.1 0.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EME29783.1 - 4.9e-07 29.9 0.2 7e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 EME29783.1 - 0.00031 20.6 0.4 0.00045 20.1 0.3 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association SnoaL_2 PF12680.2 EME29783.1 - 0.0012 19.2 0.1 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain NTP_transferase PF00483.18 EME29785.1 - 1.2e-46 159.0 0.0 1.4e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EME29785.1 - 3.5e-11 43.4 0.0 4.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EME29785.1 - 1.2e-10 40.3 3.3 4.9e-06 25.8 0.1 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME29785.1 - 8e-06 25.3 4.0 0.00046 19.6 0.8 2.9 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EME29785.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 EME29785.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PP2C PF00481.16 EME29786.1 - 2.6e-71 239.9 0.1 3.7e-71 239.5 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME29786.1 - 3.9e-06 26.7 0.8 5.8e-05 22.8 0.5 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EME29786.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C tRNA-synt_1c PF00749.16 EME29787.1 - 4.6e-105 350.7 0.0 6.3e-105 350.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4303 PF14136.1 EME29787.1 - 0.086 12.4 0.1 5.2 6.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4303) Cullin PF00888.17 EME29789.1 - 5.8e-105 352.0 10.4 2.9e-104 349.7 7.2 1.9 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME29789.1 - 3.7e-18 65.0 0.6 1.1e-17 63.5 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_rep_org_N PF09681.5 EME29789.1 - 0.013 15.0 0.2 0.97 9.0 0.0 2.9 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) Proteasome PF00227.21 EME29790.1 - 5.4e-62 208.4 0.0 1e-61 207.5 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EME29790.1 - 5.1e-12 44.8 0.2 3.3e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Aldedh PF00171.17 EME29791.1 - 1.2e-132 442.5 0.0 1.5e-132 442.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2361 PF10153.4 EME29791.1 - 0.13 12.4 0.2 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) CPL PF08144.6 EME29792.1 - 8.1e-13 48.4 0.1 4e-11 42.9 0.0 3.2 2 1 2 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 EME29792.1 - 0.00022 20.5 6.7 0.2 11.2 0.0 5.1 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat Rapsyn_N PF10579.4 EME29792.1 - 0.033 13.9 0.1 0.19 11.5 0.0 2.3 2 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region dUTPase PF00692.14 EME29793.1 - 7.4e-44 148.3 0.0 8.3e-44 148.1 0.0 1.0 1 0 0 1 1 1 1 dUTPase Asp PF00026.18 EME29794.1 - 4.8e-45 154.1 9.0 6.4e-45 153.7 6.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME29794.1 - 1.6e-15 57.0 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal CAT PF00302.13 EME29794.1 - 0.021 14.4 1.0 0.041 13.5 0.7 1.4 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Asp_protease_2 PF13650.1 EME29794.1 - 0.022 15.2 1.2 16 6.0 0.0 3.7 4 0 0 4 4 4 0 Aspartyl protease Pribosyltran PF00156.22 EME29795.1 - 2.7e-19 69.1 0.0 3.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aminotran_3 PF00202.16 EME29796.1 - 5.9e-114 380.4 0.0 7.1e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Chlorophyllase PF07224.6 EME29796.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Snf7 PF03357.16 EME29797.1 - 5.2e-22 78.0 17.0 7.5e-22 77.5 11.8 1.2 1 0 0 1 1 1 1 Snf7 DUF1955 PF09205.5 EME29797.1 - 0.92 9.0 4.7 1.6 8.2 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1955) HD_3 PF13023.1 EME29797.1 - 3.9 7.1 7.4 1.1 8.9 1.3 2.3 1 1 1 2 2 2 0 HD domain Flagellin_C PF00700.16 EME29797.1 - 4.1 7.6 8.8 0.42 10.8 0.5 2.9 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region PC_rep PF01851.17 EME29798.1 - 3.5e-27 93.0 25.0 1.6e-07 31.1 0.1 9.9 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EME29798.1 - 7.3e-20 71.0 8.9 3.4e-11 43.2 0.1 5.9 4 1 3 7 7 7 3 HEAT repeats HEAT PF02985.17 EME29798.1 - 9.7e-07 28.3 5.8 0.72 10.0 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EME29798.1 - 0.00082 19.7 6.1 1.3 9.5 0.0 5.6 4 2 3 7 7 7 2 HEAT-like repeat FolB PF02152.13 EME29798.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dihydroneopterin aldolase DUF2435 PF10363.4 EME29798.1 - 0.074 12.9 2.5 16 5.4 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) SIP1 PF04938.7 EME29799.1 - 1.3e-19 70.5 0.1 1.8e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Cpn60_TCP1 PF00118.19 EME29800.1 - 3.3e-154 514.1 7.2 3.8e-154 513.8 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_Treg PF04761.7 EME29800.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator SET PF00856.23 EME29801.1 - 7.5e-25 88.1 0.4 3.3e-24 86.0 0.3 2.2 1 1 0 1 1 1 1 SET domain FYRC PF05965.9 EME29801.1 - 8.3e-11 41.5 0.0 3.4e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 F/Y rich C-terminus zf-HC5HC2H PF13771.1 EME29801.1 - 2.1e-10 40.5 9.0 2.1e-10 40.5 6.2 5.7 4 1 3 7 7 7 1 PHD-like zinc-binding domain PHD PF00628.24 EME29801.1 - 1.7e-08 34.0 58.6 4.6e-05 23.0 3.7 5.6 5 1 1 6 6 6 4 PHD-finger FYRN PF05964.9 EME29801.1 - 2.6e-07 29.9 0.1 8.8e-07 28.2 0.1 2.0 1 0 0 1 1 1 1 F/Y-rich N-terminus C1_1 PF00130.17 EME29801.1 - 0.00026 20.6 6.6 0.00026 20.6 4.6 7.0 5 1 3 8 8 8 5 Phorbol esters/diacylglycerol binding domain (C1 domain) OCD_Mu_crystall PF02423.10 EME29802.1 - 2.9e-38 131.4 0.0 3.6e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF1508 PF07411.7 EME29802.1 - 0.13 11.6 0.0 5.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1508) HAD_2 PF13419.1 EME29803.1 - 9.4e-06 25.9 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Baculo_PEP_C PF04513.7 EME29804.1 - 0.00024 20.9 46.8 1.2 8.9 1.5 5.5 1 1 3 5 5 5 5 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EME29804.1 - 0.0039 16.9 3.8 0.0039 16.9 2.6 4.9 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) HTH_Tnp_Mu_1 PF02316.11 EME29804.1 - 0.012 15.2 3.2 2.1 8.0 0.2 3.4 1 1 1 3 3 3 0 Mu DNA-binding domain Cep57_MT_bd PF06657.8 EME29804.1 - 0.022 14.7 5.4 5.6 6.9 0.0 4.5 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Med4 PF10018.4 EME29804.1 - 0.043 13.1 13.7 0.95 8.8 0.6 3.6 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3580 PF12117.3 EME29804.1 - 0.044 13.7 2.7 20 5.1 0.1 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3580) PMT_2 PF13231.1 EME29805.1 - 2.5e-09 37.2 20.2 4.9e-09 36.2 4.4 5.0 5 2 0 5 5 5 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIP PF00230.15 EME29806.1 - 2.2e-34 118.9 7.7 3.2e-34 118.3 5.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein zf-C3HC4_3 PF13920.1 EME29807.1 - 3e-12 45.9 14.2 4.6e-12 45.4 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME29807.1 - 4.3e-05 23.4 17.1 7.3e-05 22.7 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME29807.1 - 0.015 14.7 6.3 0.034 13.6 4.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EME29807.1 - 0.16 11.8 16.2 0.31 10.8 11.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EME29807.1 - 1.1 9.0 14.3 2 8.1 9.5 1.8 1 1 1 2 2 2 0 zinc-RING finger domain SNF2_N PF00176.18 EME29808.1 - 2.1e-68 230.3 0.9 3.2e-68 229.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME29808.1 - 5.7e-16 58.1 0.1 5.7e-15 54.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME29808.1 - 0.00024 20.9 0.0 0.0016 18.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit EF-hand_like PF09279.6 EME29808.1 - 0.093 12.7 0.2 0.093 12.7 0.1 2.8 4 0 0 4 4 4 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3464 PF11947.3 EME29809.1 - 5.8e-29 100.5 0.2 7e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) DUF2207 PF09972.4 EME29809.1 - 0.014 14.0 0.2 0.017 13.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Fasciclin PF02469.17 EME29810.1 - 0.00062 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain DUF2184 PF09950.4 EME29810.1 - 0.053 12.5 0.3 0.34 9.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) RRM_1 PF00076.17 EME29811.1 - 1.3e-20 72.8 0.0 2.2e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29811.1 - 3.1e-17 62.2 0.0 4.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29811.1 - 1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME29811.1 - 0.00029 20.5 1.1 0.00069 19.3 0.8 1.6 1 0 0 1 1 1 1 Limkain b1 Nup35_RRM_2 PF14605.1 EME29811.1 - 0.0018 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF566 PF04484.7 EME29811.1 - 2.2 7.7 11.6 2.7 7.4 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MMR_HSR1 PF01926.18 EME29812.1 - 4.4e-13 49.2 0.0 1.4e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME29812.1 - 0.00021 20.5 0.1 0.085 12.1 0.0 3.1 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 EME29812.1 - 0.0015 17.6 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME29812.1 - 0.0035 16.7 0.0 0.094 12.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 EME29812.1 - 0.011 14.6 0.1 0.023 13.5 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EME29812.1 - 0.019 15.7 0.0 0.046 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EME29812.1 - 0.024 14.1 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EME29812.1 - 0.027 14.9 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EME29812.1 - 0.036 13.8 0.0 0.84 9.4 0.0 2.6 3 0 0 3 3 3 0 Dynamin family Arf PF00025.16 EME29812.1 - 0.044 13.0 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 EME29812.1 - 0.063 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EME29812.1 - 0.091 13.0 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EME29812.1 - 0.12 11.7 0.0 0.96 8.8 0.0 2.0 2 0 0 2 2 2 0 Ras family Ku_N PF03731.10 EME29813.1 - 4e-28 98.3 0.2 5.3e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EME29813.1 - 1.9e-08 33.9 0.0 3.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain DUF3399 PF11879.3 EME29813.1 - 0.24 11.6 1.8 0.58 10.4 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Ku PF02735.11 EME29814.1 - 2.3e-33 115.3 0.0 4e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EME29814.1 - 5.8e-28 97.8 0.2 9.2e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EME29814.1 - 4.6e-09 35.5 0.2 1.1e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EME29814.1 - 1.1e-07 32.3 1.7 4.2e-07 30.3 0.3 2.6 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm RLAN PF14401.1 EME29814.1 - 0.031 13.7 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain AMP-binding PF00501.23 EME29816.1 - 6e-91 304.9 0.0 7.9e-91 304.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME29816.1 - 1.1e-18 67.9 0.6 2.3e-18 66.8 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIRP PF06584.8 EME29817.1 - 1.8e-12 47.1 0.6 4.8e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 DIRP Gti1_Pac2 PF09729.4 EME29817.1 - 0.088 12.6 2.1 0.11 12.2 0.4 2.0 2 1 0 2 2 2 0 Gti1/Pac2 family H_PPase PF03030.11 EME29818.1 - 2.4e-256 852.3 23.6 2.9e-256 852.0 16.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase CorA PF01544.13 EME29819.1 - 8.5e-64 215.3 7.3 1.1e-63 215.0 5.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EME29820.1 - 8.5e-64 215.3 7.3 1.1e-63 215.0 5.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NUT_C PF12882.2 EME29821.1 - 0.024 14.2 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 NUT protein C terminal Na_Ca_ex PF01699.19 EME29822.1 - 6.6e-36 122.9 31.2 2.5e-18 66.0 9.7 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IATP PF04568.7 EME29823.1 - 0.22 11.5 1.8 0.38 10.8 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP FancD2 PF14631.1 EME29824.1 - 4.2e-22 77.2 24.9 3.1e-16 57.7 6.4 2.6 3 0 0 3 3 3 2 Fanconi anaemia protein FancD2 nuclease Aph-1 PF06105.7 EME29824.1 - 7.8e-08 31.8 21.2 2.6e-07 30.1 14.7 1.9 1 0 0 1 1 1 1 Aph-1 protein DUF2852 PF11014.3 EME29824.1 - 0.0066 16.3 2.2 0.76 9.7 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2852) AA_permease_2 PF13520.1 EME29825.1 - 1.6e-38 132.4 41.4 1.6e-38 132.4 28.7 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EME29825.1 - 1.9e-35 122.1 37.6 1.9e-35 122.1 26.1 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EME29825.1 - 1.1e-12 47.5 2.5 1.1e-12 47.5 1.7 2.9 4 0 0 4 4 4 1 C-terminus of AA_permease Nup84_Nup100 PF04121.8 EME29827.1 - 1.1e-43 149.0 9.5 5.2e-41 140.1 6.6 2.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF2348 PF09807.4 EME29827.1 - 0.0003 19.9 0.1 0.00053 19.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) NDUF_B7 PF05676.8 EME29828.1 - 1.5e-16 59.5 6.8 1.9e-16 59.2 4.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EME29828.1 - 0.00019 21.1 5.3 0.00023 20.8 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EME29828.1 - 0.0069 16.3 2.2 0.0088 16.0 1.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Kinesin PF00225.18 EME29829.1 - 3.6e-98 328.3 0.1 3.6e-98 328.3 0.0 2.5 2 1 0 2 2 2 1 Kinesin motor domain RAI1 PF08652.6 EME29830.1 - 2e-17 62.6 0.2 6.8e-17 61.0 0.1 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease PTPS PF01242.14 EME29831.1 - 1.7e-19 69.6 0.0 1.9e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase WD40 PF00400.27 EME29832.1 - 8.1e-15 54.0 9.0 1.9e-06 27.5 0.3 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EME29832.1 - 7.4e-05 21.0 0.0 0.00014 20.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME29832.1 - 0.00037 19.3 0.2 0.64 8.7 0.0 2.3 2 1 0 2 2 2 2 Nup133 N terminal like DUF1719 PF08224.6 EME29832.1 - 0.031 13.3 0.2 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Oxidored_FMN PF00724.15 EME29833.1 - 0.013 14.4 0.2 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Kua-UEV1_localn PF10520.4 EME29834.1 - 1e-20 74.1 0.5 1e-11 44.8 0.1 2.6 2 0 0 2 2 2 2 Kua-ubiquitin conjugating enzyme hybrid localisation domain CUE PF02845.11 EME29836.1 - 1.2e-05 24.6 0.0 6.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 CUE domain DUF1702 PF08012.6 EME29836.1 - 0.18 10.3 0.4 0.34 9.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) RNase_PH PF01138.16 EME29837.1 - 2.3e-36 125.0 0.2 3.7e-36 124.3 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TP_methylase PF00590.15 EME29838.1 - 2.2e-25 89.6 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DZR PF12773.2 EME29839.1 - 0.0025 17.5 6.9 0.0076 16.0 0.9 2.7 2 0 0 2 2 2 1 Double zinc ribbon DUF866 PF05907.8 EME29839.1 - 0.023 14.2 3.8 0.19 11.2 0.2 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-ribbon_3 PF13248.1 EME29839.1 - 0.57 9.4 10.4 0.74 9.1 0.6 2.8 2 1 1 3 3 3 0 zinc-ribbon domain zf-DHHC PF01529.15 EME29839.1 - 8 5.8 7.9 0.67 9.3 0.7 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-RING_2 PF13639.1 EME29840.1 - 1.2e-13 50.6 4.0 2.5e-13 49.6 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME29840.1 - 1.5e-09 37.8 1.3 7.8e-09 35.5 1.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME29840.1 - 1.4e-07 31.4 6.0 2.7e-07 30.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME29840.1 - 2.8e-07 30.0 4.7 5.7e-07 29.0 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29840.1 - 7.4e-07 28.7 4.4 1.4e-06 27.9 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME29840.1 - 8.6e-07 28.5 4.1 1.6e-06 27.6 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME29840.1 - 3.2e-05 23.6 1.1 0.00011 21.9 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME29840.1 - 0.056 13.0 3.9 0.099 12.2 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EME29840.1 - 0.22 11.3 1.1 0.48 10.2 0.8 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 EME29840.1 - 0.5 10.4 7.3 0.99 9.4 5.1 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME29840.1 - 0.57 10.1 4.2 2.1 8.3 2.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EME29840.1 - 1.5 8.5 3.9 3.5 7.3 2.7 1.7 1 1 0 1 1 1 0 PHD-finger GHMP_kinases_N PF00288.21 EME29841.1 - 1.3e-07 31.5 0.0 1.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME29841.1 - 0.0095 16.1 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M50B PF13398.1 EME29842.1 - 0.042 13.2 0.5 0.13 11.6 0.0 1.9 1 1 0 2 2 2 0 Peptidase M50B-like Peptidase_M50B PF13398.1 EME29843.1 - 0.045 13.1 0.5 0.15 11.4 0.0 1.9 1 1 0 2 2 2 0 Peptidase M50B-like TAFH PF07531.9 EME29844.1 - 0.013 15.1 0.9 0.2 11.3 0.1 2.7 3 0 0 3 3 3 0 NHR1 homology to TAF Chloroa_b-bind PF00504.16 EME29845.1 - 0.0017 18.6 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DnaJ PF00226.26 EME29846.1 - 6.1e-18 64.3 0.4 1.2e-17 63.4 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.26 EME29847.1 - 8.6e-22 76.6 0.7 1.5e-21 75.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain GFO_IDH_MocA PF01408.17 EME29848.1 - 1.1e-30 106.5 0.5 2e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME29848.1 - 9.9e-11 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 EME29848.1 - 0.00037 19.5 0.5 0.0012 17.9 0.4 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EME29848.1 - 0.00077 19.4 0.2 0.012 15.6 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.19 EME29848.1 - 0.00081 19.6 0.1 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME29848.1 - 0.0014 19.0 0.2 0.0024 18.2 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 EME29848.1 - 0.0026 18.1 0.1 0.0046 17.3 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EME29848.1 - 0.018 15.5 0.4 0.043 14.3 0.2 1.6 1 0 0 1 1 1 0 CoA binding domain 2-Hacid_dh_C PF02826.14 EME29848.1 - 0.041 13.0 0.1 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peripla_BP_1 PF00532.16 EME29848.1 - 0.058 12.5 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Gp_dh_N PF00044.19 EME29848.1 - 0.12 12.2 0.5 0.38 10.6 0.2 1.7 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME29848.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UCH PF00443.24 EME29849.1 - 2.5e-50 171.0 0.3 4.3e-50 170.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME29849.1 - 1.2e-34 120.1 0.0 2.1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EME29849.1 - 9.7e-32 110.1 0.0 8.6e-31 107.0 0.0 2.6 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EME29849.1 - 1.2e-20 73.9 0.2 1.2e-20 73.9 0.1 3.4 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal MATH PF00917.21 EME29849.1 - 6.6e-16 58.6 0.3 2.9e-14 53.3 0.1 2.7 2 0 0 2 2 2 1 MATH domain HNF-1_N PF04814.8 EME29850.1 - 0.047 13.7 1.8 0.067 13.2 1.3 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Med2 PF11214.3 EME29850.1 - 0.086 12.8 2.0 0.25 11.3 0.6 2.0 1 1 0 2 2 2 0 Mediator complex subunit 2 DUF4211 PF13926.1 EME29850.1 - 0.093 12.1 0.7 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) GCN5L1 PF06320.8 EME29850.1 - 0.35 10.6 2.2 11 5.8 0.3 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FlgN PF05130.7 EME29850.1 - 1.5 9.0 6.5 0.85 9.8 1.8 2.2 1 1 1 2 2 2 0 FlgN protein Syntaxin_2 PF14523.1 EME29850.1 - 2.4 8.2 6.8 31 4.6 4.8 2.4 1 1 0 1 1 1 0 Syntaxin-like protein CorA PF01544.13 EME29850.1 - 3 6.7 6.5 4.7 6.1 4.5 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Galactosyl_T PF01762.16 EME29851.1 - 1e-33 116.6 0.8 2.5e-32 112.0 0.4 2.8 2 1 0 2 2 2 1 Galactosyltransferase Fringe PF02434.11 EME29851.1 - 0.0067 15.6 0.1 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Fringe-like zf-RING_2 PF13639.1 EME29852.1 - 1.4e-14 53.6 4.2 1.4e-14 53.6 2.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EME29852.1 - 5.1e-09 35.6 2.5 5.1e-09 35.6 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME29852.1 - 6.8e-08 32.5 4.1 1.6e-07 31.3 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME29852.1 - 1.1e-07 31.7 4.9 1.1e-07 31.7 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME29852.1 - 1.1e-06 28.1 1.2 1.1e-06 28.1 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29852.1 - 6.5e-06 25.7 2.4 6.5e-06 25.7 1.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME29852.1 - 0.00046 19.9 3.8 0.00098 18.9 1.7 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EME29852.1 - 0.014 14.8 0.8 0.032 13.7 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DiS_P_DiS PF06750.8 EME29852.1 - 0.035 13.9 2.4 0.18 11.5 0.3 2.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Rad50_zn_hook PF04423.9 EME29852.1 - 0.037 13.4 0.5 3.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EME29852.1 - 0.04 13.6 1.6 0.073 12.8 0.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_3 PF14369.1 EME29852.1 - 0.19 11.7 0.1 0.19 11.7 0.0 2.2 3 0 0 3 3 2 0 zinc-finger DUF755 PF05501.6 EME29852.1 - 0.22 11.5 2.4 0.39 10.7 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-C3HC4_4 PF15227.1 EME29852.1 - 0.75 9.7 9.2 0.83 9.5 3.4 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EME29852.1 - 0.87 9.3 7.3 0.94 9.2 1.8 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EME29852.1 - 1.7 8.7 9.6 2.4 8.1 4.1 2.8 2 1 0 2 2 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EME29852.1 - 2.8 7.9 5.9 0.84 9.6 1.1 2.2 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 EME29852.1 - 2.9 7.5 11.4 0.042 13.4 2.3 2.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EME29853.1 - 1.1e-14 53.9 4.2 1.1e-14 53.9 2.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EME29853.1 - 4e-09 35.9 2.5 4e-09 35.9 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME29853.1 - 5e-08 32.9 4.1 1.2e-07 31.7 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME29853.1 - 8.8e-08 32.0 4.9 8.8e-08 32.0 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME29853.1 - 8.6e-07 28.5 1.2 8.6e-07 28.5 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29853.1 - 5.1e-06 26.1 2.4 5.1e-06 26.1 1.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME29853.1 - 0.00036 20.3 4.0 0.00068 19.4 1.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EME29853.1 - 0.011 15.2 0.8 0.025 14.1 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 EME29853.1 - 0.027 13.9 0.5 3.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EME29853.1 - 0.036 13.7 2.0 0.061 13.0 0.5 2.2 1 1 0 1 1 1 0 RING-type zinc-finger DiS_P_DiS PF06750.8 EME29853.1 - 0.15 11.8 0.4 0.15 11.8 0.3 2.6 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-RING_3 PF14369.1 EME29853.1 - 0.16 12.0 0.1 0.16 12.0 0.0 2.3 3 0 0 3 3 2 0 zinc-finger DUF755 PF05501.6 EME29853.1 - 0.16 12.0 2.4 0.29 11.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Prok-RING_1 PF14446.1 EME29853.1 - 0.41 10.4 6.9 0.74 9.5 1.8 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EME29853.1 - 0.62 9.9 9.5 0.66 9.9 3.4 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EME29853.1 - 0.88 9.5 9.4 2.3 8.2 4.3 2.9 2 1 0 2 2 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EME29853.1 - 1.7 8.2 11.2 0.033 13.7 2.3 2.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EME29853.1 - 2.2 8.3 6.0 0.71 9.9 1.1 2.2 2 0 0 2 2 2 0 RING-like domain V_ATPase_I PF01496.14 EME29854.1 - 9.1e-228 757.8 1.7 1e-227 757.7 1.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CBS PF00571.23 EME29855.1 - 1.3e-16 60.0 2.4 0.00033 20.3 0.0 4.5 4 0 0 4 4 4 4 CBS domain DisA_N PF02457.11 EME29855.1 - 0.11 11.6 0.2 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding PGM_PMM_I PF02878.11 EME29859.1 - 3e-38 130.3 0.0 4.9e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EME29859.1 - 3.4e-20 72.3 0.0 8.6e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EME29859.1 - 1.7e-10 40.9 0.0 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EME29859.1 - 0.016 15.1 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glycos_transf_4 PF00953.16 EME29860.1 - 1.7e-35 122.1 10.5 1.7e-35 122.1 7.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 Fringe PF02434.11 EME29861.1 - 1.7e-11 43.8 0.0 1.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.16 EME29861.1 - 8.1e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase GST_N PF02798.15 EME29863.1 - 2.8e-09 37.0 0.0 6.9e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME29863.1 - 1.6e-06 28.1 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME29863.1 - 0.0026 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME29863.1 - 0.0031 17.4 0.1 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME29864.1 - 2.8e-09 37.0 0.0 6.9e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME29864.1 - 1.6e-06 28.1 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME29864.1 - 0.0026 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME29864.1 - 0.0031 17.4 0.1 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GTP_EFTU PF00009.22 EME29865.1 - 1.2e-23 83.5 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME29865.1 - 3.4e-13 49.5 0.0 9.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME29865.1 - 1.3e-06 28.4 0.4 3.4e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME29865.1 - 0.0032 17.4 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EME29865.1 - 0.0058 17.1 0.7 0.26 11.7 0.5 2.6 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EME29865.1 - 0.0085 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 EME29865.1 - 0.037 13.5 0.3 7.7 6.0 0.0 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpc4 PF05132.9 EME29865.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 YbaB_DNA_bd PF02575.11 EME29866.1 - 9.3e-16 57.5 1.0 1.2e-15 57.1 0.7 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family UCH PF00443.24 EME29867.1 - 2e-43 148.4 0.8 2.7e-43 148.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME29867.1 - 9.2e-18 64.6 3.7 3.7e-15 56.1 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_5 PF12695.2 EME29868.1 - 5.8e-22 78.0 0.0 7.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME29868.1 - 1.6e-13 51.0 0.2 1.5e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME29868.1 - 5.7e-05 22.4 0.0 0.0039 16.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EME29868.1 - 0.0046 16.4 0.0 0.0096 15.3 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EME29868.1 - 0.0063 15.9 0.0 0.072 12.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EME29868.1 - 0.0077 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.9 EME29868.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DUF818 PF05677.7 EME29868.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.7 EME29868.1 - 0.043 12.6 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 EME29868.1 - 0.044 13.6 0.7 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 Putative lysophospholipase LSM PF01423.17 EME29869.1 - 1.1e-17 63.2 0.0 1.4e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME29869.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM PF01423.17 EME29870.1 - 1.1e-17 63.2 0.0 1.4e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME29870.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DnaJ PF00226.26 EME29871.1 - 2.9e-12 46.1 0.0 5.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 EME29871.1 - 0.00028 21.3 0.9 0.00028 21.3 0.6 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain Ribosomal_L27 PF01016.14 EME29872.1 - 4.1e-16 58.5 1.0 6.6e-16 57.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Nramp PF01566.13 EME29873.1 - 1.3e-89 300.5 24.1 1.3e-89 300.5 16.7 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Sugar_tr PF00083.19 EME29875.1 - 1.6e-37 129.1 30.2 7.7e-21 74.1 6.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME29875.1 - 2.3e-20 72.6 28.5 1.2e-16 60.3 21.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily SIMPL PF04402.9 EME29876.1 - 0.0002 21.2 1.0 0.00021 21.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) HTH_19 PF12844.2 EME29878.1 - 6.3e-12 45.3 21.2 5.4 7.1 0.0 10.1 2 1 8 10 10 10 7 Helix-turn-helix domain Baculo_PEP_C PF04513.7 EME29878.1 - 3.7e-07 30.0 81.6 0.0038 17.0 4.8 8.5 1 1 9 10 10 10 10 Baculovirus polyhedron envelope protein, PEP, C terminus Fe_dep_repr_C PF02742.10 EME29878.1 - 2.5e-05 23.8 14.7 35 4.1 0.0 9.9 10 1 1 11 11 11 0 Iron dependent repressor, metal binding and dimerisation domain Antimicrobial_7 PF08102.6 EME29878.1 - 0.00043 20.2 13.6 22 5.1 0.1 8.2 8 0 0 8 8 8 0 Scorpion antimicrobial peptide DASH_Dam1 PF08653.5 EME29878.1 - 0.00081 19.1 0.3 0.044 13.5 0.2 4.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Apolipoprotein PF01442.13 EME29878.1 - 0.002 17.6 19.0 0.0097 15.4 0.5 4.1 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain NAD_binding_4 PF07993.7 EME29878.1 - 0.0099 14.8 22.9 2.1 7.1 0.2 6.7 1 1 7 8 8 8 3 Male sterility protein FTCD_C PF04961.7 EME29878.1 - 3.6 6.9 11.0 0.29 10.5 1.8 3.7 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Translin PF01997.11 EME29879.1 - 2.6e-46 157.7 7.1 3.2e-46 157.4 4.9 1.1 1 0 0 1 1 1 1 Translin family DUF3907 PF13047.1 EME29879.1 - 0.022 14.4 2.9 0.072 12.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) DivIVA PF05103.8 EME29879.1 - 3 7.9 7.3 5 7.1 0.3 2.6 3 0 0 3 3 3 0 DivIVA protein Translin PF01997.11 EME29880.1 - 2.7e-46 157.7 7.1 3.3e-46 157.4 4.9 1.1 1 0 0 1 1 1 1 Translin family DUF3907 PF13047.1 EME29880.1 - 0.02 14.4 3.1 0.072 12.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) COG6 PF06419.6 EME29881.1 - 1.2e-72 244.9 12.9 1.7e-72 244.4 9.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Skp1 PF01466.14 EME29881.1 - 0.036 14.0 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Skp1 family, dimerisation domain AKNA PF12443.3 EME29881.1 - 0.043 13.8 1.6 4.3 7.4 0.0 3.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Rad52_Rad22 PF04098.10 EME29882.1 - 2.8e-39 134.3 0.0 4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Mgm101p PF06420.7 EME29882.1 - 0.096 12.0 0.0 0.48 9.7 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial genome maintenance MGM101 PTS_EIIB PF00367.15 EME29882.1 - 0.14 11.4 0.7 0.29 10.4 0.1 1.8 2 0 0 2 2 2 0 phosphotransferase system, EIIB DUF1995 PF09353.5 EME29883.1 - 6.6e-17 61.8 0.0 1.2e-16 60.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) Guanylate_kin PF00625.16 EME29884.1 - 2.8e-57 193.1 0.0 4.3e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EME29884.1 - 1.3e-05 25.0 0.0 4.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME29884.1 - 4.2e-05 24.3 0.0 0.00014 22.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME29884.1 - 5.7e-05 23.2 0.0 0.0002 21.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME29884.1 - 7.9e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME29884.1 - 9.7e-05 22.4 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME29884.1 - 0.00036 19.7 0.4 0.00066 18.8 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EME29884.1 - 0.0035 17.8 0.0 0.036 14.5 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 EME29884.1 - 0.0098 16.0 0.0 0.031 14.4 0.0 1.9 2 0 0 2 2 1 1 RNA helicase DAP3 PF10236.4 EME29884.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EME29884.1 - 0.013 15.4 0.1 0.03 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EME29884.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EME29884.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EME29884.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EME29884.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.18 EME29884.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EME29884.1 - 0.047 13.3 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EME29884.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EME29884.1 - 0.066 12.8 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EME29884.1 - 0.089 12.5 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EME29884.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S26e PF01283.14 EME29885.1 - 4.5e-39 133.2 13.0 4.8e-39 133.1 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Exostosin PF03016.10 EME29885.1 - 0.078 11.9 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Exostosin family RHD3 PF05879.7 EME29886.1 - 4.9e-67 226.4 10.2 6.2e-67 226.1 7.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EME29886.1 - 7.4e-05 22.6 0.0 0.00017 21.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.14 EME29886.1 - 0.00086 18.4 0.1 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.1 EME29886.1 - 0.0026 17.7 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EME29886.1 - 0.0026 17.5 0.1 0.012 15.4 0.1 2.2 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EME29886.1 - 0.0051 17.3 0.1 0.065 13.7 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein Septin PF00735.13 EME29886.1 - 0.01 14.9 0.1 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_33 PF13671.1 EME29886.1 - 0.098 12.5 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2630 PF10944.3 EME29886.1 - 0.1 12.7 2.2 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) AAA_14 PF13173.1 EME29886.1 - 0.1 12.4 3.0 0.31 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EME29886.1 - 0.15 12.9 0.3 0.79 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Aldolase_II PF00596.16 EME29887.1 - 5.5e-38 130.4 0.0 6.4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TMP-TENI PF02581.12 EME29888.1 - 4.7e-40 136.6 0.5 5.4e-40 136.4 0.4 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI QRPTase_C PF01729.14 EME29888.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Ribul_P_3_epim PF00834.14 EME29888.1 - 0.0036 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family CutC PF03932.9 EME29888.1 - 0.011 14.9 0.3 0.13 11.5 0.1 2.4 1 1 1 2 2 2 0 CutC family IGPS PF00218.16 EME29888.1 - 0.019 14.0 0.2 0.036 13.1 0.1 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Nramp PF01566.13 EME29889.1 - 5.1e-91 305.1 26.7 5.1e-91 305.1 18.5 1.8 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Peptidase_M41 PF01434.13 EME29892.1 - 2.2e-68 229.9 0.0 3.2e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME29892.1 - 3.4e-41 140.5 0.0 5.9e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EME29892.1 - 7.3e-08 32.5 1.8 7.8e-07 29.2 0.0 2.8 2 1 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EME29892.1 - 0.0003 20.5 0.0 0.00077 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME29892.1 - 0.00078 19.5 0.0 0.11 12.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EME29892.1 - 0.00083 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EME29892.1 - 0.0062 15.3 0.1 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EME29892.1 - 0.0071 17.1 0.0 0.024 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME29892.1 - 0.0098 15.8 0.2 0.091 12.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EME29892.1 - 0.02 14.3 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EME29892.1 - 0.025 13.7 0.1 0.095 11.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 EME29892.1 - 0.029 13.5 0.1 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EME29892.1 - 0.048 13.4 0.7 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EME29892.1 - 0.071 12.6 0.4 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EME29892.1 - 0.073 12.9 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EME29892.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME29892.1 - 0.14 11.5 0.5 0.27 10.6 0.3 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein 3-HAO PF06052.7 EME29893.1 - 5.4e-61 204.4 0.1 6.7e-61 204.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EME29893.1 - 6.6e-08 31.9 0.1 1.1e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EME29893.1 - 0.00022 20.6 0.1 0.00037 19.9 0.1 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EME29893.1 - 0.0076 15.9 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Nudix_N_2 PF14803.1 EME29893.1 - 0.0078 15.8 4.6 0.012 15.2 0.2 2.7 3 0 0 3 3 3 1 Nudix N-terminal Cupin_3 PF05899.7 EME29893.1 - 0.011 15.0 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EME29893.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin zf-ribbon_3 PF13248.1 EME29893.1 - 0.16 11.2 5.4 7.1 5.9 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.24 EME29893.1 - 0.42 10.3 0.2 0.42 10.3 0.1 2.8 3 1 0 3 3 3 0 PHD-finger DZR PF12773.2 EME29893.1 - 1.4 8.7 5.4 3.6 7.4 0.6 2.5 1 1 0 2 2 2 0 Double zinc ribbon DUF3716 PF12511.3 EME29893.1 - 1.4 8.5 4.3 8.5 6.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) 60KD_IMP PF02096.15 EME29894.1 - 9.4e-40 136.3 2.8 1.4e-39 135.8 1.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein LemA PF04011.7 EME29894.1 - 0.031 13.3 0.1 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 LemA family DUF4142 PF13628.1 EME29894.1 - 0.041 13.9 1.8 0.053 13.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) DUF1090 PF06476.7 EME29894.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) BING4CT PF08149.6 EME29895.1 - 4.9e-36 122.1 0.0 1.6e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EME29895.1 - 1.3e-09 37.5 0.0 2.9e-08 33.2 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Med7 PF05983.6 EME29896.1 - 1.6e-14 53.9 0.2 2.2e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 MED7 protein 2-Hacid_dh_C PF02826.14 EME29897.1 - 5.2e-44 149.5 0.1 6.6e-43 145.9 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME29897.1 - 3e-21 75.2 0.0 4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME29897.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME29897.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3513 PF12026.3 EME29897.1 - 0.034 13.6 0.1 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) 3HCDH_N PF02737.13 EME29897.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EME29897.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME29897.1 - 0.071 13.2 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME29897.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Nop10p PF04135.7 EME29898.1 - 0.026 14.2 2.2 0.19 11.4 0.1 2.8 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family DUF1272 PF06906.6 EME29898.1 - 0.34 10.7 7.5 0.26 11.1 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) DnaJ_CXXCXGXG PF00684.14 EME29898.1 - 0.56 10.2 16.1 1.4 9.0 9.3 2.8 2 1 0 2 2 2 0 DnaJ central domain zf-RING_3 PF14369.1 EME29898.1 - 3.1 7.8 7.5 48 4.0 0.0 3.0 2 1 0 2 2 2 0 zinc-finger DUF2358 PF10184.4 EME29899.1 - 4.6e-20 71.6 0.4 6.8e-20 71.0 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) NUDIX PF00293.23 EME29900.1 - 2.3e-15 56.4 0.1 3.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.1 EME29900.1 - 4.5e-15 55.0 2.1 1.1e-14 53.8 1.5 1.7 1 0 0 1 1 1 1 Nudix N-terminal zinc_ribbon_5 PF13719.1 EME29900.1 - 0.0086 15.6 1.3 1.9 8.1 2.4 2.4 1 1 1 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EME29900.1 - 0.011 15.5 0.5 0.025 14.3 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.1 EME29900.1 - 0.012 15.2 0.8 0.73 9.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EME29900.1 - 0.079 12.4 4.8 0.24 10.9 0.0 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RRN7 PF11781.3 EME29900.1 - 0.16 11.5 3.8 2.5 7.6 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2039 PF10217.4 EME29900.1 - 0.18 11.8 4.0 1.3 9.0 1.1 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-MYND PF01753.13 EME29900.1 - 0.21 11.4 5.2 2.5 8.0 3.5 2.3 1 1 1 2 2 2 0 MYND finger XAP5 PF04921.9 EME29901.1 - 3.7e-76 255.8 4.8 5.5e-76 255.2 3.3 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator zf-U1 PF06220.7 EME29902.1 - 5.2e-18 64.3 6.3 7.9e-18 63.7 4.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EME29902.1 - 0.001 19.1 2.2 0.001 19.1 1.6 1.9 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding GerPC PF10737.4 EME29902.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC zf-met PF12874.2 EME29902.1 - 1.6 9.0 3.6 25 5.2 2.5 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type HTH_3 PF01381.17 EME29907.1 - 2.9e-05 23.8 0.0 7.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EME29907.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EME29907.1 - 0.025 14.6 0.2 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_20 PF00982.16 EME29908.1 - 2.9e-131 438.2 0.0 4.6e-131 437.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME29908.1 - 5.2e-38 130.2 0.0 5.4e-35 120.4 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.7 EME29908.1 - 0.00064 19.3 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DNA_photolyase PF00875.13 EME29909.1 - 1.7e-43 148.2 0.0 2.4e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EME29909.1 - 2e-09 37.0 0.0 2.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase FAE1_CUT1_RppA PF08392.7 EME29910.1 - 2.1e-123 411.0 0.0 3.1e-123 410.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EME29910.1 - 1.2e-11 44.5 0.0 3.7e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 EME29910.1 - 1.5e-11 44.4 0.0 3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.5 EME29910.1 - 0.00037 20.1 0.0 0.00082 18.9 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.14 EME29910.1 - 0.00038 19.7 0.0 0.00063 19.0 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain LRR_6 PF13516.1 EME29911.1 - 6.6e-36 118.3 39.7 0.017 15.1 0.2 17.1 15 2 2 17 17 17 13 Leucine Rich repeat LRR_4 PF12799.2 EME29911.1 - 1.7e-35 120.0 28.3 0.00026 20.5 1.7 12.1 2 2 12 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME29911.1 - 2.5e-23 81.5 38.5 3.9e-05 23.3 1.2 8.9 4 4 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EME29911.1 - 4.6e-06 25.9 38.2 1.9 8.8 0.0 13.2 11 5 1 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 EME29911.1 - 4.7e-06 25.9 30.9 19 6.0 0.0 13.7 12 2 0 12 12 12 1 Leucine rich repeat LRR_9 PF14580.1 EME29911.1 - 0.13 11.8 11.4 0.18 11.3 0.3 4.6 2 2 4 6 6 6 0 Leucine-rich repeat CK2S PF15011.1 EME29912.1 - 0.00087 19.1 2.6 0.0012 18.6 1.7 1.4 1 1 0 1 1 1 1 Casein Kinase 2 substrate Seryl_tRNA_N PF02403.17 EME29912.1 - 0.026 14.5 1.2 0.026 14.5 0.8 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EME29912.1 - 0.16 11.6 2.9 0.26 11.0 1.3 1.8 1 1 1 2 2 2 0 Homeobox associated leucine zipper Homez PF11569.3 EME29912.1 - 0.62 9.1 4.7 0.26 10.3 0.2 2.5 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez PALP PF00291.20 EME29913.1 - 4.4e-71 239.6 0.6 6e-71 239.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EME29913.1 - 2.6e-49 164.7 0.0 3.2e-25 87.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase RTP PF02334.11 EME29913.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Replication terminator protein DUF493 PF04359.9 EME29914.1 - 2.6e-05 24.4 1.0 2.6e-05 24.4 0.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF493) SEC-C PF02810.10 EME29915.1 - 7.3e-06 25.3 1.5 1.3e-05 24.5 1.0 1.4 1 0 0 1 1 1 1 SEC-C motif F_actin_cap_B PF01115.12 EME29915.1 - 0.044 12.9 0.5 0.063 12.4 0.4 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit PsbU PF06514.6 EME29916.1 - 1.4e-34 117.7 0.4 1.4e-34 117.7 0.3 1.4 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.2 EME29916.1 - 2.8e-09 36.7 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Es2 PF09751.4 EME29917.1 - 9.7e-40 137.2 9.7 7.1e-38 131.1 6.7 2.1 1 1 0 1 1 1 1 Nuclear protein Es2 MSP PF01716.13 EME29918.1 - 1.5e-90 302.5 0.5 1.9e-90 302.2 0.4 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide DHH PF01368.15 EME29919.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DHH family BBS2_N PF14781.1 EME29919.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal tRNA_edit PF04073.10 EME29923.1 - 6.6e-05 22.7 0.0 0.00019 21.2 0.0 1.7 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Peptidase_S24 PF00717.18 EME29924.1 - 1.6e-10 40.4 0.3 4.5e-10 39.0 0.1 1.8 1 1 1 2 2 2 1 Peptidase S24-like DUF2108 PF09881.4 EME29924.1 - 0.23 11.2 5.0 2.5 8.0 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) Peptidase_S24 PF00717.18 EME29925.1 - 1.4e-10 40.6 0.4 3.8e-10 39.2 0.1 1.8 1 1 1 2 2 2 1 Peptidase S24-like DUF2108 PF09881.4 EME29925.1 - 0.19 11.5 5.0 2.2 8.1 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) YlbD_coat PF14071.1 EME29926.1 - 0.017 15.2 1.8 0.085 12.9 2.1 1.6 2 0 0 2 2 2 0 Putative coat protein DUF2080 PF09853.4 EME29926.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) DAP PF15228.1 EME29926.1 - 0.28 11.9 5.3 0.4 11.4 3.6 1.3 1 0 0 1 1 1 0 Death-associated protein LUC7 PF03194.10 EME29926.1 - 0.29 10.6 6.0 0.32 10.4 4.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus WD40 PF00400.27 EME29927.1 - 3.7e-41 137.5 17.2 3.4e-08 33.0 0.2 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Bromodomain PF00439.20 EME29927.1 - 1.3e-10 41.0 0.0 2.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Auxin_resp PF06507.8 EME29927.1 - 3.4e-05 23.5 0.3 0.00011 21.9 0.2 1.9 1 0 0 1 1 1 1 Auxin response factor Nucleoporin_N PF08801.6 EME29927.1 - 0.00034 19.4 0.3 0.23 10.1 0.1 2.6 2 0 0 2 2 2 2 Nup133 N terminal like adh_short_C2 PF13561.1 EME29928.1 - 3e-34 118.8 0.0 3.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME29928.1 - 5.6e-32 110.9 0.1 6.8e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME29928.1 - 6.5e-14 51.9 0.2 8.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME29928.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME29928.1 - 0.006 15.6 0.3 0.016 14.3 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EME29928.1 - 0.0068 16.5 0.3 0.016 15.2 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EME29928.1 - 0.072 12.8 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 5_nucleotid PF05761.9 EME29929.1 - 1.6e-143 478.4 5.5 2.1e-143 478.1 3.8 1.0 1 0 0 1 1 1 1 5' nucleotidase family SLBP_RNA_bind PF15247.1 EME29929.1 - 0.027 14.2 0.8 0.5 10.1 0.1 2.7 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain BLOC1_2 PF10046.4 EME29929.1 - 0.052 13.6 0.4 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hydrolase_like PF13242.1 EME29929.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like zf-LSD1 PF06943.7 EME29930.1 - 8.7e-05 22.0 0.3 8.7e-05 22.0 0.2 3.9 3 1 1 4 4 4 1 LSD1 zinc finger DZR PF12773.2 EME29930.1 - 0.016 15.0 17.1 3.1 7.6 5.9 3.4 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EME29930.1 - 0.016 14.9 19.8 0.22 11.2 0.7 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.12 EME29930.1 - 0.1 12.1 11.5 0.16 11.5 0.2 4.1 4 0 0 4 4 4 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.8 EME29930.1 - 2.1 7.8 17.3 2.7 7.5 1.0 3.8 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit UbiA PF01040.13 EME29931.1 - 2.9e-38 131.5 11.4 4.5e-38 130.9 7.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-RING_2 PF13639.1 EME29932.1 - 4.9e-13 48.6 6.9 4.9e-13 48.6 4.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME29932.1 - 1.1e-09 38.1 7.0 3.1e-09 36.7 4.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME29932.1 - 2.7e-07 30.1 3.5 2.7e-07 30.1 2.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME29932.1 - 7.6e-07 29.1 9.4 1.1e-06 28.5 5.3 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME29932.1 - 8.3e-07 28.5 6.6 2.3e-06 27.1 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME29932.1 - 8.3e-06 25.4 4.9 8.3e-06 25.4 3.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME29932.1 - 0.0036 17.1 4.5 0.012 15.4 3.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CReP_N PF10472.4 EME29932.1 - 0.038 12.7 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor FANCL_C PF11793.3 EME29932.1 - 0.41 10.6 11.8 0.82 9.6 5.2 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 EME29932.1 - 2.2 8.0 10.9 1.3 8.7 4.6 2.7 2 1 0 2 2 2 0 PHD-finger RINGv PF12906.2 EME29932.1 - 3.5 7.7 12.5 0.25 11.4 4.4 2.3 2 1 0 2 2 2 0 RING-variant domain Queuosine_synth PF02547.10 EME29933.1 - 1e-108 363.1 0.0 8.9e-82 274.5 0.0 2.0 2 0 0 2 2 2 2 Queuosine biosynthesis protein FAD_binding_1 PF00667.15 EME29934.1 - 1.3e-31 109.7 0.0 2.3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EME29934.1 - 1.5e-11 44.8 0.0 3.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nup160 PF11715.3 EME29934.1 - 0.013 13.7 0.0 0.02 13.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NAD_binding_6 PF08030.7 EME29934.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain GST_N PF02798.15 EME29935.1 - 6.3e-16 58.3 0.0 1.4e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME29935.1 - 2.8e-12 46.4 0.4 4.9e-12 45.6 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME29935.1 - 6.4e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME29935.1 - 7e-05 22.9 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME29935.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bac_globin PF01152.16 EME29935.1 - 0.1 12.5 1.3 28 4.7 0.0 3.0 2 1 1 3 3 3 0 Bacterial-like globin B56 PF01603.15 EME29936.1 - 1.1e-126 422.7 2.1 1.4e-126 422.4 1.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Complex1_49kDa PF00346.14 EME29937.1 - 1.1e-128 427.9 0.0 1.4e-128 427.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit eRF1_1 PF03463.10 EME29938.1 - 2.7e-45 153.1 0.1 4.7e-45 152.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EME29938.1 - 3.6e-24 85.5 0.1 6.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EME29938.1 - 1.5e-20 73.5 0.0 3.7e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 FAA_hydrolase PF01557.13 EME29939.1 - 7.3e-56 189.0 0.0 9.1e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HAD_2 PF13419.1 EME29940.1 - 2.7e-06 27.7 0.0 2.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Carbpep_Y_N PF05388.6 EME29940.1 - 0.0071 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide CLTH PF10607.4 EME29941.1 - 9.8e-26 90.1 0.8 1.9e-25 89.2 0.5 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EME29941.1 - 4.8e-21 75.1 0.1 8.7e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EME29941.1 - 0.0044 16.7 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 LisH DUF1863 PF08937.6 EME29941.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TauD PF02668.11 EME29942.1 - 3.3e-33 115.4 0.0 4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 EME29943.1 - 1.2e-62 212.0 14.9 1.5e-62 211.6 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME29943.1 - 4e-28 98.1 19.0 5.6e-28 97.6 13.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME29943.1 - 0.026 12.7 7.3 0.0092 14.2 1.9 2.1 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EME29943.1 - 0.033 12.2 1.7 0.054 11.5 0.5 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.27 EME29944.1 - 8.5e-69 225.1 22.1 1.5e-13 50.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME29944.1 - 1.1e-10 41.5 0.0 2.4e-05 24.1 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME29944.1 - 0.0007 17.8 2.1 0.075 11.1 0.0 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EME29944.1 - 0.0014 17.0 0.7 1.3 7.2 0.0 3.3 2 2 2 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EME29944.1 - 0.0016 17.3 0.3 0.6 8.8 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 EME29945.1 - 2.3e-66 217.4 20.9 3.2e-12 45.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME29945.1 - 4.1e-11 42.9 0.0 2.6e-05 24.0 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME29945.1 - 0.0023 16.1 1.5 0.081 11.0 0.0 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EME29945.1 - 0.023 13.0 0.0 1.4 7.1 0.0 3.0 2 2 2 4 4 4 0 Cytochrome D1 heme domain tRNA-synt_1b PF00579.20 EME29946.1 - 4.6e-77 259.0 0.0 5.7e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Mito_carr PF00153.22 EME29947.1 - 3.8e-73 241.2 1.7 2.1e-25 88.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MAPEG PF01124.13 EME29947.1 - 0.007 15.9 0.6 0.26 10.9 0.0 2.6 1 1 1 2 2 2 2 MAPEG family FAD_binding_3 PF01494.14 EME29948.1 - 2.2e-15 56.5 0.0 1.1e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EME29948.1 - 3.2e-06 26.1 0.0 1e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DCX PF03607.12 EME29948.1 - 0.051 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Doublecortin NAD_binding_8 PF13450.1 EME29948.1 - 0.085 12.8 1.0 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain OTU PF02338.14 EME29949.1 - 1.9e-12 47.8 0.1 6.6e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME29949.1 - 5.5e-08 32.4 1.5 0.00014 21.3 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain DnaB_C PF03796.10 EME29949.1 - 0.0063 15.4 0.1 0.0086 14.9 0.1 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Hydantoinase_B PF02538.9 EME29950.1 - 7.6e-187 621.7 0.0 2.2e-186 620.1 0.0 1.7 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EME29950.1 - 3.3e-90 302.1 0.0 7.1e-90 301.0 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EME29950.1 - 1.5e-31 109.2 0.2 1.5e-29 102.7 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region PEMT PF04191.8 EME29951.1 - 4.3e-14 52.4 0.0 8.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EME29951.1 - 5.1e-09 35.1 0.0 8.7e-09 34.4 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EME29951.1 - 3.2e-05 24.0 0.0 8.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EME29951.1 - 6e-05 22.4 0.0 8.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EME29951.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 NnrU protein HSF_DNA-bind PF00447.12 EME29952.1 - 6.1e-29 100.2 0.0 1.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_L33 PF00471.15 EME29953.1 - 1.7e-18 66.5 0.0 2.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 NTP_transf_3 PF12804.2 EME29956.1 - 9.1e-12 45.3 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EME29956.1 - 1.1e-07 31.4 0.0 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Glyco_tranf_2_3 PF13641.1 EME29956.1 - 0.00064 19.5 0.0 0.00076 19.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Paf67 PF10255.4 EME29958.1 - 6.6e-133 443.4 0.6 8.9e-133 443.0 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Ribosomal_S9 PF00380.14 EME29959.1 - 2.4e-35 121.4 0.0 5.5e-35 120.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 RasGEF_N_2 PF14663.1 EME29960.1 - 0.04 13.8 1.5 1.4 8.8 0.1 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Rtf2 PF04641.7 EME29961.1 - 3e-09 36.4 0.7 8.8e-09 34.9 0.5 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Pro_isomerase PF00160.16 EME29961.1 - 1.1e-05 25.6 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EME29961.1 - 0.0049 16.7 0.0 0.04 13.8 0.0 2.4 3 0 0 3 3 3 1 U-box domain RRM_1 PF00076.17 EME29962.1 - 3.6e-40 135.4 0.1 4.1e-20 71.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME29962.1 - 5.6e-37 125.5 0.0 1.9e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME29962.1 - 1.7e-14 53.3 0.3 2.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME29962.1 - 3.9e-05 23.3 0.7 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif NID PF07292.8 EME29962.1 - 0.00014 21.8 0.0 1 9.4 0.0 2.7 3 0 0 3 3 3 2 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 EME29962.1 - 0.0013 18.5 1.4 0.03 14.1 0.1 2.4 1 1 1 2 2 2 1 RNA binding motif OB_RNB PF08206.6 EME29962.1 - 0.011 15.1 1.1 0.56 9.7 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2817 PF10994.3 EME29962.1 - 0.052 12.6 0.1 0.052 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) DUF3161 PF11362.3 EME29963.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DUF4375 PF14300.1 EME29963.1 - 0.039 13.9 0.1 0.32 11.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF3161 PF11362.3 EME29964.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) DUF4375 PF14300.1 EME29964.1 - 0.039 13.9 0.1 0.32 11.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) UPF0079 PF02367.12 EME29965.1 - 4.3e-25 87.7 0.0 5.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EME29965.1 - 2.8e-06 27.4 0.0 3.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EME29965.1 - 0.00011 21.2 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 EME29965.1 - 0.0066 16.6 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME29965.1 - 0.0066 16.5 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EME29965.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME29965.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EME29965.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EME29965.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EME29965.1 - 0.02 15.2 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME29965.1 - 0.029 14.2 0.1 1.4 8.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_13 PF13166.1 EME29965.1 - 0.03 12.7 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME29965.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EME29965.1 - 0.046 14.0 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EME29965.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EME29965.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 EME29965.1 - 0.052 13.0 0.1 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EME29965.1 - 0.053 13.8 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EME29965.1 - 0.056 13.1 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EME29965.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EME29965.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EME29965.1 - 0.13 13.1 0.0 0.25 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EME29965.1 - 0.13 11.9 0.0 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EME29965.1 - 0.13 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EME29965.1 - 0.14 11.1 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Glyco_hydro_35 PF01301.14 EME29966.1 - 5.1e-85 285.6 1.0 6.8e-85 285.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EME29966.1 - 1e-34 119.1 3.2 1.5e-19 70.3 0.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EME29966.1 - 2.1e-32 111.9 1.1 3.2e-32 111.3 0.8 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 Glyco_hydro_42 PF02449.10 EME29966.1 - 2.5e-10 40.0 0.2 6.8e-08 32.0 0.1 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom3 PF13363.1 EME29966.1 - 1.1e-08 34.2 0.0 2.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EME29966.1 - 0.00027 20.2 0.0 0.00047 19.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EME29967.1 - 2.3e-88 296.6 5.5 3.4e-88 296.0 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EME29967.1 - 2.1e-44 150.3 4.6 3.7e-24 85.1 0.6 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EME29967.1 - 2e-30 105.5 1.8 4.2e-30 104.4 1.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EME29967.1 - 5.9e-12 44.8 0.1 1.1e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 Beta-galactosidase, domain 3 RVP PF00077.15 EME29967.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease ADH_zinc_N PF00107.21 EME29968.1 - 9.6e-26 89.8 0.3 1.6e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME29968.1 - 8.4e-15 55.7 0.0 3.3e-14 53.8 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME29968.1 - 2.2e-12 46.7 0.1 1.5e-10 40.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.13 EME29968.1 - 0.007 16.3 0.3 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 HupF/HypC family FTR1 PF03239.9 EME29970.1 - 0.031 13.2 0.9 0.036 13.0 0.6 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family YbgT_YccB PF08173.6 EME29970.1 - 0.12 12.1 0.3 0.12 12.1 0.2 2.3 2 1 0 2 2 2 0 Membrane bound YbgT-like protein Clathrin PF00637.15 EME29971.1 - 5.5e-178 583.6 1.1 1.1e-30 106.1 0.0 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EME29971.1 - 7.3e-30 102.6 0.2 3.3e-29 100.5 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EME29971.1 - 1.1e-23 81.8 0.2 6.7e-05 22.9 0.0 6.4 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_7 PF13176.1 EME29971.1 - 2.8e-07 29.8 4.1 0.91 9.4 0.0 6.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EME29971.1 - 0.002 16.9 3.3 0.49 9.1 0.0 4.4 3 1 2 5 5 5 1 Coatomer WD associated region PPR PF01535.15 EME29971.1 - 0.0038 17.1 4.2 0.79 9.8 0.0 5.6 6 0 0 6 6 5 1 PPR repeat Clathrin-link PF09268.5 EME29971.1 - 0.0068 15.4 0.0 0.019 13.9 0.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 EME29971.1 - 0.02 14.8 12.2 0.53 10.2 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME29971.1 - 0.028 15.0 23.1 9.9 7.1 0.0 10.9 13 1 0 13 13 11 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.9 EME29971.1 - 0.052 12.9 0.1 0.76 9.2 0.0 2.8 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family TPR_19 PF14559.1 EME29971.1 - 0.078 13.3 8.7 6.5 7.1 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Vps39_1 PF10366.4 EME29971.1 - 1.1 9.2 10.9 9.6 6.2 0.0 6.2 7 1 1 8 8 8 0 Vacuolar sorting protein 39 domain 1 TGS PF02824.16 EME29972.1 - 4.7e-21 74.3 0.0 9.1e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EME29972.1 - 1.2e-15 57.4 0.0 2e-15 56.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME29972.1 - 3e-10 39.6 0.1 1.1e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.1 EME29972.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME29972.1 - 0.021 15.2 0.1 0.057 13.9 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein DUF258 PF03193.11 EME29972.1 - 0.037 13.2 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arf PF00025.16 EME29972.1 - 0.056 12.6 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 EME29972.1 - 0.063 13.5 0.2 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MCM PF00493.18 EME29972.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family SRPRB PF09439.5 EME29972.1 - 0.096 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EME29972.1 - 0.1 12.1 0.4 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 EME29972.1 - 0.11 11.2 0.0 0.25 10.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein Dynamin_N PF00350.18 EME29972.1 - 0.12 12.1 0.5 9 6.0 0.1 2.4 1 1 1 2 2 2 0 Dynamin family TGS PF02824.16 EME29973.1 - 5.3e-21 74.2 0.0 9.9e-21 73.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EME29973.1 - 6.4e-20 71.2 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME29973.1 - 4e-13 48.9 0.2 1.2e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EME29973.1 - 0.00015 21.6 0.1 0.034 13.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EME29973.1 - 0.00055 20.4 0.0 0.0016 18.9 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_28 PF13521.1 EME29973.1 - 0.016 15.1 0.3 0.039 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EME29973.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF258 PF03193.11 EME29973.1 - 0.058 12.5 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME29973.1 - 0.068 13.4 0.3 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MCM PF00493.18 EME29973.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family SRPRB PF09439.5 EME29973.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 EME29973.1 - 0.11 11.2 0.0 0.27 9.9 0.0 1.6 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 EME29973.1 - 0.12 11.9 0.4 5.5 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain 4HBT PF03061.17 EME29974.1 - 1.5e-09 37.8 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EME29974.1 - 4.4e-08 33.5 0.0 7.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily FKBP_C PF00254.23 EME29975.1 - 1.2e-28 98.9 0.0 1.9e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Methyltransf_11 PF08241.7 EME29976.1 - 9.1e-13 48.5 0.0 3.5e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29976.1 - 1.7e-12 47.3 0.0 3.9e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29976.1 - 6.5e-08 32.3 0.0 6.5e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME29976.1 - 1.3e-07 31.9 0.0 9.9e-06 25.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EME29976.1 - 2.6e-05 23.9 0.0 5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EME29976.1 - 0.00043 20.6 0.1 1.6 9.1 0.0 2.7 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EME29976.1 - 0.0017 18.8 0.3 0.25 11.9 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME29976.1 - 0.0038 16.3 0.0 0.1 11.6 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EME29976.1 - 0.0067 14.8 0.0 0.05 11.9 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EME29976.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Prefoldin PF02996.12 EME29979.1 - 6.6e-10 38.6 0.0 2.3e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EME29979.1 - 0.0041 16.8 0.0 0.03 14.1 0.0 2.4 1 1 1 2 2 2 1 Prefoldin subunit FG-GAP_2 PF14312.1 EME29980.1 - 1.8e-09 37.4 3.3 0.15 12.0 0.0 6.0 6 0 0 6 6 6 4 FG-GAP repeat AAA_22 PF13401.1 EME29982.1 - 0.039 14.1 0.0 0.16 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain SAM_2 PF07647.12 EME29982.1 - 0.086 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1654 PF07867.6 EME29983.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Arch_ATPase PF01637.13 EME29984.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Peptidase_S9 PF00326.16 EME29985.1 - 9.4e-37 126.2 0.0 1.3e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME29985.1 - 3.2e-11 43.1 0.0 8.3e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EME29985.1 - 8e-09 35.1 0.0 3.4e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EME29985.1 - 1.2e-08 35.1 0.0 2.9e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EME29985.1 - 5e-07 29.4 0.3 0.00025 20.5 0.5 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EME29985.1 - 0.00042 20.0 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EME29985.1 - 0.035 13.6 0.5 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF3974 PF13120.1 EME29986.1 - 0.0015 18.3 2.0 0.0033 17.2 1.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3974) DUF1673 PF07895.6 EME29986.1 - 0.041 13.4 1.2 0.13 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4496 PF14908.1 EME29986.1 - 0.084 12.7 1.1 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) CRF PF00473.12 EME29986.1 - 0.99 9.5 3.9 3.2 7.9 2.7 1.9 1 0 0 1 1 1 0 Corticotropin-releasing factor family DASH_Duo1 PF08651.5 EME29986.1 - 5.3 6.6 11.2 3.9 7.1 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 FA_desaturase PF00487.19 EME29987.1 - 3e-33 115.3 22.3 3e-33 115.3 15.5 1.9 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EME29987.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4131 PF13567.1 EME29988.1 - 6.8 6.0 12.4 2.4e+02 1.0 8.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) adh_short PF00106.20 EME29989.1 - 4.1e-23 82.1 0.1 5.1e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME29989.1 - 6.4e-10 39.1 0.0 8.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME29989.1 - 1.8e-06 27.7 0.1 2.4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME29989.1 - 0.0024 17.6 0.2 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EME29989.1 - 0.0096 15.0 0.1 0.021 13.8 0.1 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KH_1 PF00013.24 EME29990.1 - 4.3e-05 23.0 0.0 8.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EME29990.1 - 7.6e-05 22.2 0.0 0.00021 20.8 0.0 1.8 1 0 0 1 1 1 1 KH domain eIF3g PF12353.3 EME29990.1 - 0.016 15.1 0.1 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G mono-CXXC PF15626.1 EME29990.1 - 0.06 13.2 1.3 0.39 10.6 0.1 2.6 2 0 0 2 2 2 0 single CXXC unit 4HBT_3 PF13622.1 EME29990.1 - 0.12 12.0 3.2 0.24 11.1 2.2 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily SHMT PF00464.14 EME29991.1 - 3.6e-187 621.6 0.0 4.2e-187 621.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SPOR PF05036.8 EME29991.1 - 0.093 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Sporulation related domain Branch PF02485.16 EME29992.1 - 4.4e-32 111.1 0.7 8.3e-32 110.2 0.5 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF21 PF01595.15 EME29993.1 - 9.6e-34 116.2 11.2 1.4e-33 115.7 7.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME29993.1 - 5.6e-21 74.0 0.2 2.4e-13 49.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.12 EME29993.1 - 1.3e-15 56.9 0.0 3.1e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain HhH-GPD PF00730.20 EME29994.1 - 1.3e-14 54.3 0.0 3.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EME29994.1 - 1.7e-10 40.2 0.1 8.5e-10 38.0 0.0 2.2 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 EME29994.1 - 8.5e-05 22.0 0.0 0.00026 20.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Transposase_20 PF02371.11 EME29994.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Trehalose_PPase PF02358.11 EME29995.1 - 3.7e-51 173.3 0.0 4.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EME29995.1 - 1.5e-10 41.1 0.0 1.5e-06 27.9 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME29995.1 - 0.00092 19.4 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Toprim_4 PF13662.1 EME29995.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Toprim domain S6PP PF05116.8 EME29995.1 - 0.093 12.0 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase zf-LYAR PF08790.6 EME29996.1 - 6.1e-12 45.0 2.9 6.1e-12 45.0 2.0 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-met PF12874.2 EME29996.1 - 3e-07 30.3 2.0 3e-07 30.3 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME29996.1 - 1.8e-06 27.9 1.4 1.8e-06 27.9 1.0 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME29996.1 - 0.15 12.1 9.9 0.11 12.5 1.0 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EME29996.1 - 0.26 11.2 0.2 0.26 11.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-U1 PF06220.7 EME29996.1 - 0.41 10.2 3.5 0.34 10.5 0.1 2.3 2 0 0 2 2 2 0 U1 zinc finger Prok-RING_1 PF14446.1 EME29996.1 - 4.3 7.1 10.9 16 5.2 5.7 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 IBR PF01485.16 EME29996.1 - 9.6 6.1 13.3 3.9e+02 1.0 9.2 2.5 1 1 0 1 1 1 0 IBR domain NAD_binding_1 PF00175.16 EME29997.1 - 4e-26 91.7 0.0 6.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME29997.1 - 2.3e-06 27.6 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.15 EME29997.1 - 1.5e-05 24.5 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_6 PF08030.7 EME29997.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain CHCH PF06747.8 EME29998.1 - 0.0061 16.4 2.3 0.0094 15.8 1.6 1.3 1 0 0 1 1 1 1 CHCH domain Nop16 PF09420.5 EME29998.1 - 0.071 13.2 5.2 0.1 12.7 3.6 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF4326 PF14216.1 EME29998.1 - 0.077 13.5 2.9 14 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) DUF763 PF05559.6 EME29998.1 - 0.083 11.8 1.5 0.098 11.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) ResB PF05140.9 EME29998.1 - 1.2 7.6 3.0 1.4 7.3 2.1 1.1 1 0 0 1 1 1 0 ResB-like family MutS_V PF00488.16 EME29999.1 - 1.4e-83 279.9 0.0 2.2e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME29999.1 - 1.6e-37 129.2 3.0 3.6e-37 128.1 2.1 1.7 1 0 0 1 1 1 1 MutS domain III Methyltransf_12 PF08242.7 EME29999.1 - 3e-21 75.7 1.7 1.7e-20 73.2 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME29999.1 - 3.5e-21 75.3 0.0 2.2e-20 72.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME29999.1 - 5.6e-19 68.4 0.1 5.6e-18 65.2 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME29999.1 - 7.3e-19 68.3 0.0 2e-17 63.7 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain MutS_I PF01624.15 EME29999.1 - 9.8e-18 64.2 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain I Methyltransf_25 PF13649.1 EME29999.1 - 1.5e-16 60.5 0.0 6.2e-16 58.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME29999.1 - 3e-15 56.2 0.0 1.2e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MutS_II PF05188.12 EME29999.1 - 1.6e-10 41.1 0.1 4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME29999.1 - 1.5e-09 37.8 0.3 6.7e-09 35.8 0.2 2.3 2 0 0 2 2 1 1 MutS family domain IV Ubie_methyltran PF01209.13 EME29999.1 - 1.4e-07 30.8 0.0 3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME29999.1 - 6.3e-07 29.4 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EME29999.1 - 2e-05 23.4 0.0 4.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EME29999.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EME29999.1 - 0.00078 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 EME29999.1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EME29999.1 - 0.0085 15.7 2.3 0.019 14.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_5 PF01795.14 EME29999.1 - 0.018 14.3 0.0 0.099 11.9 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family Pox_MCEL PF03291.11 EME29999.1 - 0.021 13.7 0.0 0.076 11.8 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme AAA_23 PF13476.1 EME29999.1 - 0.027 14.8 1.9 0.91 9.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain DNA_repr_REX1B PF14966.1 EME29999.1 - 0.2 12.0 2.7 9.1 6.7 0.0 3.8 4 0 0 4 4 4 0 DNA repair REX1-B RCC1 PF00415.13 EME30000.1 - 1.8e-93 306.5 20.8 7.3e-14 51.7 0.4 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME30000.1 - 2.7e-43 144.7 37.1 6.9e-10 38.2 0.2 7.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF2317 PF10079.4 EME30000.1 - 0.011 14.4 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Kelch_6 PF13964.1 EME30000.1 - 0.24 11.6 2.5 25 5.2 0.0 3.7 3 1 0 3 3 3 0 Kelch motif DSHCT PF08148.7 EME30001.1 - 1.5e-52 177.4 0.1 3.9e-52 176.1 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EME30001.1 - 1.6e-20 73.3 0.1 4.2e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME30001.1 - 7.4e-08 32.1 0.0 2.2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EME30001.1 - 8.9e-06 25.0 0.2 0.0031 16.6 0.0 2.4 2 0 0 2 2 2 2 rRNA-processing arch domain ResIII PF04851.10 EME30001.1 - 0.00028 20.7 0.2 0.019 14.7 0.1 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 EME30002.1 - 1.8e-48 164.9 0.0 3.3e-48 164.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30002.1 - 1.7e-16 60.1 0.0 2.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME30002.1 - 0.0025 17.6 0.0 0.011 15.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME30002.1 - 0.0063 15.8 0.1 0.04 13.2 0.0 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.1 EME30002.1 - 0.16 10.9 0.2 0.56 9.1 0.1 1.8 1 1 1 2 2 2 0 Kinase-like DUF1092 PF06485.6 EME30003.1 - 1.9e-67 227.0 0.0 2.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1092) TFIID-18kDa PF02269.11 EME30004.1 - 1.3e-05 24.8 0.1 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ras PF00071.17 EME30005.1 - 1.1e-50 171.1 0.0 1.3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME30005.1 - 1.8e-17 63.8 0.0 2.6e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME30005.1 - 1.4e-09 37.4 0.0 1.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME30005.1 - 2.1e-05 24.0 0.0 0.00026 20.4 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME30005.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME30005.1 - 0.09 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.27 EME30006.1 - 1.3e-11 43.9 17.8 0.0033 17.2 0.4 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME30006.1 - 0.16 11.4 1.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.1 EME30007.1 - 1.7e-11 44.2 0.5 1.7e-11 44.2 0.3 2.5 2 1 1 3 3 3 2 HEAT repeats Fes1 PF08609.5 EME30007.1 - 2.3e-10 40.8 1.8 6.7e-10 39.3 1.3 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 EME30007.1 - 1.9e-07 30.5 5.8 0.00078 19.3 0.1 4.2 3 2 1 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EME30007.1 - 2.3e-05 24.6 5.9 6.5e-05 23.2 0.2 3.5 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 EME30007.1 - 0.00018 21.4 0.3 0.0029 17.4 0.0 2.7 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EME30007.1 - 0.0031 17.3 0.2 0.42 10.5 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF4042 PF13251.1 EME30007.1 - 0.015 14.7 2.5 5.3 6.4 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) DUF4495 PF14906.1 EME30007.1 - 0.035 13.0 0.5 0.98 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4495) Cohesin_HEAT PF12765.2 EME30007.1 - 0.041 13.8 1.1 0.093 12.7 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.11 EME30007.1 - 0.3 11.6 1.5 5.3 7.8 0.0 3.7 4 1 0 4 4 3 0 PBS lyase HEAT-like repeat RTTN_N PF14726.1 EME30007.1 - 0.43 11.1 4.2 6.1 7.4 0.8 3.5 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning LSM PF01423.17 EME30008.1 - 2.1e-16 59.2 0.6 2.4e-16 59.0 0.4 1.1 1 0 0 1 1 1 1 LSM domain MIF4G PF02854.14 EME30009.1 - 1.3e-30 106.4 17.3 8.9e-18 64.4 0.1 3.8 3 1 1 4 4 4 3 MIF4G domain Upf2 PF04050.9 EME30009.1 - 1.8e-15 57.1 15.5 1.8e-15 57.1 10.7 3.4 4 1 0 4 4 4 1 Up-frameshift suppressor 2 Glutaredoxin2_C PF04399.8 EME30009.1 - 0.013 15.0 0.2 0.04 13.4 0.2 1.9 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain AAA PF00004.24 EME30010.1 - 2e-35 121.8 0.0 4.1e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME30010.1 - 6.1e-08 31.9 0.0 2.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME30010.1 - 2.2e-06 28.5 0.0 7.7e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME30010.1 - 4.3e-05 23.2 0.1 0.00029 20.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME30010.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EME30010.1 - 0.0004 19.5 0.0 0.00093 18.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EME30010.1 - 0.00042 20.3 0.2 0.0058 16.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EME30010.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME30010.1 - 0.00058 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME30010.1 - 0.0015 18.6 0.1 0.029 14.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EME30010.1 - 0.0029 16.3 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EME30010.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Epimerase PF01370.16 EME30010.1 - 0.0065 15.9 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_19 PF13245.1 EME30010.1 - 0.0071 16.0 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EME30010.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EME30010.1 - 0.031 13.2 0.0 0.069 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EME30010.1 - 0.038 13.1 0.2 5.9 5.9 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 EME30010.1 - 0.039 13.5 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EME30010.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 EME30010.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EME30010.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EME30011.1 - 1.9e-35 121.9 0.0 4e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME30011.1 - 5.6e-08 32.1 0.0 2e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME30011.1 - 2e-06 28.6 0.0 7.5e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME30011.1 - 4.1e-05 23.3 0.1 0.00028 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME30011.1 - 5.2e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EME30011.1 - 0.00039 19.5 0.0 0.00092 18.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EME30011.1 - 0.0004 20.4 0.3 0.011 15.7 0.0 2.6 2 1 0 2 2 1 1 AAA ATPase domain Epimerase PF01370.16 EME30011.1 - 0.0004 19.8 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_18 PF13238.1 EME30011.1 - 0.00042 20.6 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME30011.1 - 0.00056 19.8 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME30011.1 - 0.0015 18.7 0.1 0.032 14.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EME30011.1 - 0.0028 16.4 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EME30011.1 - 0.0048 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME30011.1 - 0.0069 16.1 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain NAD_binding_2 PF03446.10 EME30011.1 - 0.0089 15.8 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_28 PF13521.1 EME30011.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EME30011.1 - 0.029 13.2 0.0 0.067 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) 2-Hacid_dh_C PF02826.14 EME30011.1 - 0.035 13.2 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KaiC PF06745.8 EME30011.1 - 0.036 13.1 0.2 5.8 5.9 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.1 EME30011.1 - 0.038 13.5 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UDPG_MGDP_dh_N PF03721.9 EME30011.1 - 0.038 13.3 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IstB_IS21 PF01695.12 EME30011.1 - 0.059 12.7 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein ThiF PF00899.16 EME30011.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ThiF family CPT PF07931.7 EME30011.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ApbA PF02558.11 EME30011.1 - 0.1 12.0 0.1 0.38 10.1 0.0 2.0 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EME30011.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EME30011.1 - 0.14 12.1 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding ResIII PF04851.10 EME30011.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EME30011.1 - 0.16 12.1 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IGPS PF00218.16 EME30012.1 - 1.8e-34 118.9 0.0 2.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EME30012.1 - 9.1e-05 21.5 0.3 0.044 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EME30012.1 - 0.0014 17.9 0.3 0.039 13.2 0.0 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EME30012.1 - 0.0039 16.2 1.8 0.021 13.9 0.4 2.6 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EME30012.1 - 0.0071 15.6 0.6 0.072 12.3 0.0 2.3 2 1 0 2 2 2 1 PcrB family PA PF02225.17 EME30012.1 - 0.037 13.7 0.2 4.3 7.0 0.0 2.6 2 1 0 2 2 2 0 PA domain DHO_dh PF01180.16 EME30012.1 - 0.065 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF3895 PF13034.1 EME30013.1 - 0.079 12.4 0.3 2.2 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) bZIP_1 PF00170.16 EME30014.1 - 5.6e-06 26.2 6.0 5.6e-06 26.2 4.2 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME30014.1 - 2.5e-05 23.9 8.3 7.9e-05 22.3 5.7 1.9 1 0 0 1 1 1 1 Basic region leucine zipper HeLo PF14479.1 EME30014.1 - 0.034 13.8 3.0 0.053 13.2 2.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation PcfJ PF14284.1 EME30014.1 - 0.13 11.7 5.0 0.026 14.0 1.0 1.5 2 0 0 2 2 2 0 PcfJ-like protein CTP_transf_1 PF01148.15 EME30016.1 - 1.1e-69 235.0 24.6 1.8e-69 234.2 17.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase family Herpes_UL52 PF03121.10 EME30017.1 - 1.6e-12 46.9 0.1 3.8e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase MTS PF05175.9 EME30018.1 - 3.1e-16 59.2 0.0 3.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME30018.1 - 1.5e-15 57.2 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME30018.1 - 1.1e-14 54.2 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30018.1 - 2.8e-11 43.7 0.0 7e-11 42.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30018.1 - 3.3e-10 40.2 0.0 6.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME30018.1 - 3.9e-10 39.3 0.1 5.3e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EME30018.1 - 1e-09 38.9 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME30018.1 - 7e-09 35.1 0.0 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 EME30018.1 - 3.8e-08 33.0 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EME30018.1 - 4.5e-07 29.2 0.0 6.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_23 PF13489.1 EME30018.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EME30018.1 - 1.2e-05 24.1 0.0 1.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EME30018.1 - 5.4e-05 23.6 0.0 8.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME30018.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 EME30018.1 - 0.0059 16.3 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EME30018.1 - 0.01 15.3 0.0 0.072 12.5 0.0 2.0 2 0 0 2 2 2 0 DNA methylase PCMT PF01135.14 EME30018.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EME30018.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EME30018.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase FtsJ PF01728.14 EME30018.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF43 PF01861.11 EME30018.1 - 0.051 12.5 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_15 PF09445.5 EME30018.1 - 0.091 12.3 0.3 0.2 11.2 0.2 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Amino_oxidase PF01593.19 EME30019.1 - 5.8e-20 71.7 0.0 5.9e-19 68.4 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME30019.1 - 2.8e-15 56.0 0.0 5.9e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME30019.1 - 3.2e-06 26.3 0.0 0.00082 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME30019.1 - 0.00023 20.3 0.1 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME30019.1 - 0.0009 17.8 0.0 0.038 12.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EME30019.1 - 0.0011 19.3 0.1 0.0028 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME30019.1 - 0.0037 16.3 0.1 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EME30019.1 - 0.0043 16.9 0.1 0.029 14.2 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME30019.1 - 0.0066 15.3 0.1 0.02 13.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EME30019.1 - 0.013 14.4 0.1 0.13 11.1 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EME30019.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME30019.1 - 0.23 10.0 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.19 EME30020.1 - 3.9e-19 69.0 0.0 3e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME30020.1 - 5.4e-15 55.1 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME30020.1 - 1.3e-05 24.2 0.0 0.0016 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME30020.1 - 0.00045 19.3 0.1 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME30020.1 - 0.0021 18.3 0.0 0.0055 17.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tranf_2_4 PF13704.1 EME30020.1 - 0.0032 17.7 0.1 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 HI0933_like PF03486.9 EME30020.1 - 0.0033 15.9 0.0 0.077 11.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EME30020.1 - 0.0073 15.4 0.1 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EME30020.1 - 0.014 15.2 0.1 0.057 13.2 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME30020.1 - 0.017 14.0 0.1 0.039 12.8 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EME30020.1 - 0.038 12.8 0.1 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein His_biosynth PF00977.16 EME30021.1 - 1.3e-26 93.2 0.0 1.8e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DNA_pol_B PF00136.16 EME30022.1 - 1.6e-141 472.2 0.1 2.3e-141 471.7 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME30022.1 - 1.1e-76 257.8 0.0 1.8e-76 257.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EME30022.1 - 6.9e-20 70.8 12.7 1.4e-19 69.8 8.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EME30022.1 - 0.056 12.1 2.9 0.039 12.6 0.4 2.0 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral Transglut_prok PF09017.5 EME30023.1 - 0.049 12.7 0.5 0.051 12.7 0.3 1.1 1 0 0 1 1 1 0 Microbial transglutaminase KTI12 PF08433.5 EME30024.1 - 1e-69 234.7 1.4 1.2e-69 234.5 1.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EME30024.1 - 1.5e-10 41.0 0.2 2.1e-09 37.3 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EME30024.1 - 8.2e-05 23.4 0.2 0.00024 21.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME30024.1 - 0.0002 21.6 0.1 0.00063 20.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.13 EME30024.1 - 0.0014 17.7 2.4 0.015 14.3 0.3 2.6 2 1 0 2 2 2 1 6-phosphofructo-2-kinase PRK PF00485.13 EME30024.1 - 0.014 14.9 0.0 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 EME30024.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase 7TMR-HDED PF07697.6 EME30024.1 - 0.033 13.9 0.8 7.5 6.2 0.4 2.1 2 0 0 2 2 2 0 7TM-HD extracellular AAA_22 PF13401.1 EME30024.1 - 0.038 14.1 0.4 0.13 12.3 0.0 2.1 2 2 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME30024.1 - 0.061 13.2 0.6 0.78 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EME30024.1 - 0.093 12.2 0.9 1.2 8.6 0.0 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EME30024.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Cupin_1 PF00190.17 EME30025.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin MMR_HSR1 PF01926.18 EME30026.1 - 7.4e-20 71.0 0.1 1.3e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.12 EME30026.1 - 3.5e-17 61.7 0.4 6.5e-17 60.8 0.3 1.5 1 0 0 1 1 1 1 KH domain Dynamin_N PF00350.18 EME30026.1 - 2e-10 40.7 0.7 1.8e-05 24.6 0.4 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EME30026.1 - 2.1e-10 40.3 0.1 1.8e-08 34.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME30026.1 - 8.8e-10 38.0 0.3 2.9e-09 36.4 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EME30026.1 - 6.6e-09 35.4 0.4 2.4e-07 30.3 0.3 2.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 EME30026.1 - 9.1e-08 31.4 0.7 1.9e-07 30.4 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Arf PF00025.16 EME30026.1 - 1.4e-07 30.9 0.7 4.6e-07 29.2 0.5 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME30026.1 - 2.1e-07 31.4 0.1 4.9e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 EME30026.1 - 0.00022 20.6 2.4 0.03 13.7 0.1 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 EME30026.1 - 0.00035 19.7 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EME30026.1 - 0.0007 18.8 0.2 0.002 17.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EME30026.1 - 0.00089 18.5 0.7 0.0015 17.8 0.5 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EME30026.1 - 0.0021 17.5 0.1 0.012 15.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Ras PF00071.17 EME30026.1 - 0.0045 16.3 0.1 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.1 EME30026.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EME30026.1 - 0.0093 16.3 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME30026.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EME30026.1 - 0.025 14.0 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EME30026.1 - 0.026 14.8 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EME30026.1 - 0.17 11.8 0.4 0.54 10.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain Methyltransf_31 PF13847.1 EME30027.1 - 5.2e-24 84.5 0.0 1.2e-23 83.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30027.1 - 4.2e-13 49.6 0.0 7.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME30027.1 - 3.2e-11 43.2 0.0 5.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME30027.1 - 1.5e-09 38.3 0.0 2.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME30027.1 - 1.2e-08 34.3 0.0 2.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME30027.1 - 2e-08 34.6 0.0 5.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30027.1 - 2.5e-07 30.9 0.1 6.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30027.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME30027.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EME30027.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EME30027.1 - 0.047 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EME30027.1 - 0.096 12.2 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Hypothetical methyltransferase Spt4 PF06093.8 EME30028.1 - 5.9e-26 90.1 0.1 7.4e-26 89.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF1364 PF07102.7 EME30028.1 - 0.06 13.2 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) SF3b10 PF07189.6 EME30029.1 - 8.8e-26 89.5 0.1 1.1e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) ARID PF01388.16 EME30030.1 - 9.5e-25 86.2 4.2 9.4e-19 67.0 0.3 2.8 3 0 0 3 3 3 2 ARID/BRIGHT DNA binding domain PHD PF00628.24 EME30030.1 - 2.2e-05 24.0 10.9 2.2e-05 24.0 7.5 2.3 2 0 0 2 2 2 1 PHD-finger Helitron_like_N PF14214.1 EME30030.1 - 0.0068 16.1 0.5 0.025 14.3 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus SGT1 PF07093.6 EME30030.1 - 0.011 14.1 0.7 0.02 13.3 0.5 1.3 1 0 0 1 1 1 0 SGT1 protein Prok-RING_1 PF14446.1 EME30030.1 - 0.021 14.5 3.0 0.074 12.7 2.1 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Peptidase_M1 PF01433.15 EME30031.1 - 4.3e-141 470.5 0.0 6.1e-141 470.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EME30031.1 - 6.1e-60 203.1 0.3 1.1e-59 202.3 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EME30031.1 - 6.9e-22 77.8 0.2 1.6e-21 76.6 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily ADH_zinc_N PF00107.21 EME30032.1 - 5.1e-19 68.1 0.0 1e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME30032.1 - 2.6e-09 38.0 0.0 6.8e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME30032.1 - 7.5e-05 22.4 0.2 0.00037 20.2 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EME30032.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF525 PF04379.9 EME30033.1 - 1.1e-10 41.3 0.1 5.4e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF525) UVR PF02151.14 EME30033.1 - 0.019 14.4 0.3 0.068 12.7 0.2 2.0 1 0 0 1 1 1 0 UvrB/uvrC motif Ribosomal_L14 PF00238.14 EME30034.1 - 3.4e-35 120.4 0.0 3.9e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RCC1 PF00415.13 EME30035.1 - 4.6e-89 292.4 21.9 2e-16 59.8 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME30035.1 - 2.7e-45 151.0 41.9 3.5e-09 36.0 1.1 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.9 EME30035.1 - 0.25 11.1 2.0 12 5.7 0.0 3.6 4 0 0 4 4 4 0 Peptidase family C25, C terminal ig-like domain Sec23_trunk PF04811.10 EME30036.1 - 1.7e-64 217.4 0.0 2.5e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME30036.1 - 3.1e-31 106.8 0.6 5.4e-31 106.0 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EME30036.1 - 4.7e-28 97.5 0.1 9e-28 96.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EME30036.1 - 2e-13 49.6 8.8 4.2e-13 48.6 6.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EME30036.1 - 7.4e-07 28.7 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-S_biosyn PF01521.15 EME30037.1 - 1.9e-15 56.7 0.0 3.1e-15 56.0 0.0 1.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Rsd_AlgQ PF04353.8 EME30038.1 - 1.6 8.4 8.0 1.2 8.8 0.5 3.2 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Aminotran_1_2 PF00155.16 EME30039.1 - 3.8e-40 137.9 0.0 5.2e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EME30039.1 - 7e-05 21.6 0.0 0.005 15.5 0.0 2.2 2 0 0 2 2 2 2 Allinase LSM PF01423.17 EME30040.1 - 1.8e-14 52.9 0.2 2.2e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME30040.1 - 5.6e-05 22.9 0.1 6.1e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 EME30041.1 - 8e-17 60.5 0.1 9.8e-17 60.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME30041.1 - 6.7e-05 22.7 0.2 9.7e-05 22.2 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Rft-1 PF04506.8 EME30043.1 - 1.8e-37 128.9 23.6 1.1e-33 116.5 9.2 2.5 2 1 0 3 3 3 2 Rft protein RNase_P_p30 PF01876.11 EME30044.1 - 4.8e-33 113.5 0.0 9.6e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit p30 Sterol_MT_C PF08498.5 EME30045.1 - 5.9e-22 77.3 0.1 1.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EME30045.1 - 1.2e-17 64.1 0.0 2.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME30045.1 - 3.7e-13 49.3 0.0 5.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME30045.1 - 1.2e-11 44.1 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EME30045.1 - 3e-10 40.3 0.0 7.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME30045.1 - 7.5e-10 38.3 0.0 7.3e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EME30045.1 - 4e-08 33.1 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30045.1 - 7.7e-08 32.7 0.0 2.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME30045.1 - 2e-06 28.3 0.0 4.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30045.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME30045.1 - 0.018 14.4 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Phosphorylase PF00343.15 EME30046.1 - 0 1043.5 0.0 0 1043.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase EF-hand_7 PF13499.1 EME30047.1 - 4.5e-17 61.9 2.8 8.2e-09 35.4 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME30047.1 - 5.2e-16 56.6 0.4 1.4e-05 24.0 0.3 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EME30047.1 - 2.5e-12 45.5 0.3 0.00062 19.4 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EME30047.1 - 2.2e-10 39.3 0.8 0.00031 19.9 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EME30047.1 - 8.6e-10 38.0 0.9 0.0027 17.3 0.1 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 EME30047.1 - 2e-05 24.3 0.1 7.2e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EME30047.1 - 2.5e-05 24.2 0.1 0.019 15.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EME30047.1 - 2.3 7.9 7.8 4 7.1 0.1 3.8 2 2 2 4 4 4 0 EF hand IF2_N PF04760.10 EME30047.1 - 4 7.1 6.4 2.8 7.6 0.1 3.0 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region DAO PF01266.19 EME30048.1 - 1.2e-50 172.4 0.0 3e-50 171.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME30048.1 - 8.4e-05 22.8 1.6 0.00021 21.6 1.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME30048.1 - 0.00041 19.3 5.8 0.00057 18.8 3.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EME30048.1 - 0.0006 19.7 0.1 0.0015 18.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME30048.1 - 0.0018 17.2 3.2 0.034 12.9 2.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME30048.1 - 0.0031 16.5 1.1 0.046 12.6 1.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EME30048.1 - 0.013 15.5 2.3 0.03 14.3 1.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME30048.1 - 0.028 13.5 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EME30048.1 - 0.05 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EME30048.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EME30048.1 - 0.17 11.9 0.5 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME30048.1 - 0.84 8.0 2.9 8.8 4.6 2.4 2.1 2 0 0 2 2 2 0 HI0933-like protein Acyl-CoA_dh_1 PF00441.19 EME30049.1 - 8.5e-24 84.3 0.0 1.7e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME30049.1 - 4.1e-05 23.0 0.2 7.4e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME30049.1 - 0.0086 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME30049.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain PEPcase PF00311.12 EME30052.1 - 1.2e-275 916.4 0.0 1.4e-275 916.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EME30052.1 - 1.4e-08 33.5 0.0 2.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Thiolase_N PF00108.18 EME30053.1 - 1.8e-93 312.3 0.4 1.8e-93 312.3 0.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME30053.1 - 1.9e-41 140.3 0.3 6.3e-41 138.6 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME30053.1 - 9.6e-05 21.9 0.5 0.00094 18.7 0.2 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain JAB PF01398.16 EME30054.1 - 1.2e-34 118.5 0.3 3.2e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EME30054.1 - 3.2e-27 94.9 4.4 1.7e-26 92.5 3.0 2.1 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EME30054.1 - 1.7e-07 30.7 0.0 3.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TFIID_20kDa PF03847.8 EME30054.1 - 0.038 14.2 2.4 0.062 13.5 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PRTase_1 PF11202.3 EME30054.1 - 0.13 11.1 3.0 0.16 10.9 1.3 1.7 2 1 0 2 2 2 0 Phosphoribosyl transferase (PRTase) CHCH PF06747.8 EME30055.1 - 3.5e-08 33.1 12.4 0.00018 21.3 2.4 2.8 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EME30055.1 - 0.00045 20.1 14.4 0.057 13.4 2.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EME30055.1 - 0.1 12.4 15.9 0.12 12.1 3.3 2.2 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EME30055.1 - 0.57 10.2 14.6 1.1 9.3 1.2 2.5 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Hormone_5 PF00184.12 EME30055.1 - 0.99 9.9 7.8 1.3 9.6 2.6 2.3 1 1 1 2 2 2 0 Neurohypophysial hormones, C-terminal Domain UPF0203 PF05254.7 EME30055.1 - 1.1 9.1 11.4 1.7 8.5 0.2 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) Colipase-like PF15083.1 EME30055.1 - 3.5 7.6 9.9 8.2 6.4 1.6 2.1 1 1 1 2 2 2 0 Colipase-like GCK PF07802.6 EME30055.1 - 4.2 7.5 10.0 0.78 9.9 2.0 2.2 1 1 1 2 2 2 0 GCK domain NDUF_B7 PF05676.8 EME30055.1 - 9.1 5.7 10.3 14 5.1 2.8 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) NAD_binding_10 PF13460.1 EME30056.1 - 1.9e-13 50.8 0.0 2.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME30056.1 - 2.8e-12 46.4 0.0 3.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EME30056.1 - 9.2e-11 41.1 0.0 1.4e-08 34.0 0.0 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EME30056.1 - 6.4e-09 34.9 0.0 1e-07 30.9 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME30056.1 - 9.6e-08 31.2 0.3 0.013 14.4 0.0 3.1 2 1 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EME30056.1 - 1.2e-07 31.4 0.0 5.9e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SR-25 PF10500.4 EME30056.1 - 9.8 5.5 9.4 16 4.9 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAP PF00188.21 EME30057.1 - 4.5e-17 62.6 0.4 6e-17 62.2 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Herpes_capsid PF06112.6 EME30057.1 - 3.6 7.6 4.6 66 3.5 0.0 2.3 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein WD40 PF00400.27 EME30058.1 - 1.2e-26 91.6 11.3 5.7e-05 22.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME30058.1 - 0.0026 17.4 0.0 0.046 13.4 0.0 2.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A VPS28 PF03997.7 EME30059.1 - 1.7e-40 138.6 0.6 2.3e-40 138.2 0.0 1.5 2 0 0 2 2 2 1 VPS28 protein TFIIA PF03153.8 EME30059.1 - 0.22 11.3 5.6 0.3 10.9 3.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EB1 PF03271.12 EME30060.1 - 7e-16 57.9 1.6 7e-16 57.9 1.1 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 EME30060.1 - 1.3e-07 31.6 0.5 3.6e-07 30.2 0.2 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EME30060.1 - 0.00034 20.1 0.1 0.00095 18.7 0.0 1.8 2 0 0 2 2 2 1 CAMSAP CH domain Cyt-b5 PF00173.23 EME30061.1 - 4.4e-24 84.0 0.1 1.1e-23 82.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EME30061.1 - 2.8e-09 37.3 15.3 2.8e-09 37.3 10.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CcmE PF03100.10 EME30063.1 - 7.4e-36 122.6 0.1 2.3e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 CcmE WD40 PF00400.27 EME30064.1 - 1.3e-08 34.3 1.3 0.19 11.6 0.0 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EME30064.1 - 0.0013 18.9 1.3 3.4 8.0 0.1 4.5 3 1 1 4 4 4 1 PQQ-like domain PQQ_2 PF13360.1 EME30064.1 - 0.0014 18.1 0.2 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 PQQ-like domain DUF4394 PF14339.1 EME30064.1 - 0.1 11.8 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) MutS_V PF00488.16 EME30065.1 - 4.3e-70 235.7 0.0 7.1e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME30065.1 - 1.7e-32 112.8 2.4 4.1e-32 111.6 1.6 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EME30065.1 - 3.4e-31 107.6 0.0 9.1e-31 106.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EME30065.1 - 2.6e-06 27.4 3.5 2.9e-06 27.3 0.4 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 EME30065.1 - 0.0001 22.3 0.6 0.0013 18.8 0.0 2.9 2 0 0 2 2 2 1 MutS domain II MutS_V PF00488.16 EME30066.1 - 4.5e-70 235.7 0.0 7.3e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME30066.1 - 1.6e-32 112.9 2.4 4.2e-32 111.5 1.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EME30066.1 - 1.4e-27 95.9 0.8 7.8e-25 87.1 0.0 2.8 1 1 1 2 2 2 2 MutS domain I MutS_IV PF05190.13 EME30066.1 - 7.2e-07 29.2 1.7 3e-06 27.3 0.4 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EME30066.1 - 0.0001 22.3 0.6 0.0013 18.8 0.0 2.9 2 0 0 2 2 2 1 MutS domain II CMD PF02627.15 EME30067.1 - 4.9e-08 32.7 0.1 1e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.8 EME30067.1 - 0.0075 15.0 0.0 0.011 14.4 0.0 1.2 1 1 0 1 1 1 1 PA26 p53-induced protein (sestrin) Sec23_trunk PF04811.10 EME30068.1 - 1.8e-44 151.9 0.0 2.8e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME30068.1 - 2.6e-21 74.9 0.3 6.1e-21 73.8 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EME30068.1 - 6e-15 54.5 0.7 1.2e-14 53.5 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EME30068.1 - 4.7e-12 46.2 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EME30068.1 - 1.6e-06 27.6 0.0 3.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat K_channel_TID PF07941.6 EME30068.1 - 0.51 10.6 2.6 1.3 9.2 1.2 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Sec23_trunk PF04811.10 EME30069.1 - 1.8e-44 151.9 0.0 2.7e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME30069.1 - 2.5e-21 75.0 0.3 5.9e-21 73.8 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EME30069.1 - 5.8e-15 54.5 0.7 1.2e-14 53.5 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EME30069.1 - 4.6e-12 46.2 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EME30069.1 - 1.6e-06 27.6 0.0 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat K_channel_TID PF07941.6 EME30069.1 - 0.49 10.6 2.6 1.3 9.2 1.2 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain bZIP_2 PF07716.10 EME30070.1 - 0.00015 21.5 18.9 0.00015 21.5 13.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EME30070.1 - 0.0015 18.4 18.6 0.0015 18.4 12.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EME30070.1 - 0.34 11.2 13.1 0.95 9.8 9.1 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor Complex1_LYR PF05347.10 EME30071.1 - 0.00041 20.0 1.3 0.00057 19.6 0.3 1.7 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME30071.1 - 0.017 15.2 0.5 0.033 14.3 0.3 1.5 1 0 0 1 1 1 0 Complex1_LYR-like TFIIB PF00382.14 EME30072.1 - 2.5e-18 65.6 0.0 1.3e-07 31.2 0.0 3.1 2 1 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EME30072.1 - 5.8e-15 54.3 1.0 9.3e-15 53.6 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EME30072.1 - 0.0023 17.3 0.6 0.0053 16.1 0.4 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain Ribosomal_S27e PF01667.12 EME30072.1 - 0.0029 17.1 0.8 0.005 16.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S27 zf-ribbon_3 PF13248.1 EME30072.1 - 0.13 11.5 0.8 0.32 10.2 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 EME30072.1 - 0.43 10.2 2.1 21 4.8 0.2 2.7 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DNA_RNApol_7kD PF03604.8 EME30072.1 - 1 8.8 4.8 2.8 7.4 3.3 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Rxt3 PF08642.5 EME30073.1 - 5.3e-08 33.0 0.2 2.4e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EME30073.1 - 0.00015 21.6 0.1 0.00033 20.5 0.1 1.5 1 0 0 1 1 1 1 LCCL domain SNF2_N PF00176.18 EME30074.1 - 4e-29 101.3 0.3 7.9e-29 100.3 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 EME30074.1 - 4.7e-11 42.3 1.3 1e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 HSA LigT_PEase PF02834.11 EME30076.1 - 2.9e-12 46.3 0.6 8.1e-07 28.9 0.0 3.5 3 1 0 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 EME30076.1 - 1e-09 38.2 0.0 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 EME30076.1 - 2.2e-06 27.5 0.1 1.1e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain EGF_2 PF07974.8 EME30077.1 - 1.6e-12 47.3 47.3 7.7e-06 25.9 8.2 3.4 2 1 1 3 3 3 3 EGF-like domain Laminin_EGF PF00053.19 EME30077.1 - 0.37 10.7 36.7 0.18 11.7 4.8 3.5 1 1 2 3 3 3 0 Laminin EGF-like (Domains III and V) Kelch_4 PF13418.1 EME30077.1 - 0.42 10.4 2.8 2.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain EGF_2 PF07974.8 EME30078.1 - 5.9e-08 32.7 39.3 5e-05 23.3 3.4 3.4 2 1 1 3 3 3 3 EGF-like domain Kelch_4 PF13418.1 EME30078.1 - 0.39 10.5 2.8 2.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Channel_Tsx PF03502.8 EME30079.1 - 0.035 13.9 0.1 0.04 13.7 0.0 1.0 1 0 0 1 1 1 0 Nucleoside-specific channel-forming protein, Tsx Arch_ATPase PF01637.13 EME30081.1 - 0.0074 16.0 0.2 0.065 12.9 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase Arch_ATPase PF01637.13 EME30082.1 - 4.8e-06 26.4 0.1 3.2e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Archaeal ATPase SAM_1 PF00536.25 EME30083.1 - 0.001 19.2 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_22 PF13401.1 EME30083.1 - 0.018 15.2 0.0 0.066 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME30084.1 - 0.038 13.6 0.1 0.4 10.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EME30085.1 - 0.051 13.7 0.1 0.29 11.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain Ribonuc_red_lgC PF02867.10 EME30087.1 - 4.1e-219 728.6 0.0 5.3e-219 728.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EME30087.1 - 6.2e-25 86.8 0.0 2.2e-24 85.0 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EME30087.1 - 2.3e-17 63.2 0.1 9.4e-17 61.2 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EME30087.1 - 0.0039 15.3 0.0 0.0063 14.6 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Ribosomal_S4e PF00900.15 EME30088.1 - 8.8e-31 105.4 0.1 5.5e-30 102.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EME30088.1 - 3.3e-20 71.6 8.8 5.8e-20 70.8 6.1 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EME30088.1 - 7.9e-06 25.2 0.0 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EME30088.1 - 0.001 18.7 1.4 0.0026 17.4 0.1 2.6 2 0 0 2 2 2 1 KOW motif Tcp10_C PF07202.8 EME30089.1 - 1.2e-17 64.0 1.2 1.6e-12 47.3 0.0 2.9 1 1 2 3 3 3 2 T-complex protein 10 C-terminus MORN_2 PF07661.8 EME30089.1 - 0.0093 15.8 0.3 7.6 6.9 0.0 4.1 4 1 0 4 4 4 1 MORN repeat variant DUF4520 PF15016.1 EME30089.1 - 0.023 14.2 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Tcp10_C PF07202.8 EME30090.1 - 1.2e-17 64.0 1.2 1.6e-12 47.3 0.0 2.9 1 1 2 3 3 3 2 T-complex protein 10 C-terminus MORN_2 PF07661.8 EME30090.1 - 0.0093 15.8 0.3 7.6 6.9 0.0 4.1 4 1 0 4 4 4 1 MORN repeat variant DUF4520 PF15016.1 EME30090.1 - 0.023 14.2 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) PALP PF00291.20 EME30092.1 - 4.4e-56 190.3 0.1 5.3e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-AN1 PF01428.11 EME30092.1 - 0.09 12.6 0.7 0.17 11.7 0.5 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger zf-ZPR1 PF03367.8 EME30093.1 - 3.3e-83 276.6 0.6 1.7e-46 157.3 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain NUDIX PF00293.23 EME30093.1 - 0.019 14.5 0.0 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 NUDIX domain TerY-C PF15616.1 EME30093.1 - 0.062 13.2 9.4 0.75 9.7 0.8 3.2 3 0 0 3 3 3 0 TerY-C metal binding domain HypA PF01155.14 EME30093.1 - 4.7 6.9 9.9 3.1 7.5 1.6 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Ribosomal_S15 PF00312.17 EME30094.1 - 6e-15 54.7 0.3 1.1e-14 53.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 RelA_SpoT PF04607.12 EME30095.1 - 1.8e-27 95.6 0.4 5.8e-27 94.0 0.3 1.9 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Methyltransf_31 PF13847.1 EME30096.1 - 3.4e-12 46.2 0.1 2.8e-10 39.9 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30096.1 - 2.2e-11 44.1 0.1 1.1e-09 38.6 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME30096.1 - 5.4e-11 42.4 0.2 9.3e-11 41.7 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME30096.1 - 3.7e-10 39.3 0.0 1e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EME30096.1 - 1.6e-09 38.3 0.0 1.4e-05 25.5 0.0 2.6 2 1 0 3 3 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EME30096.1 - 6.4e-09 36.1 0.1 3.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30096.1 - 1.7e-08 34.8 0.6 1.8e-06 28.3 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30096.1 - 2e-07 31.0 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Zip PF02535.17 EME30096.1 - 0.00049 19.1 3.1 0.00054 19.0 2.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UPF0020 PF01170.13 EME30096.1 - 0.00073 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EME30096.1 - 0.0053 16.1 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain CMAS PF02353.15 EME30096.1 - 0.044 12.8 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EME30096.1 - 0.055 12.9 0.3 4.2 6.8 0.0 2.4 2 1 1 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NicO PF03824.11 EME30096.1 - 0.57 9.4 5.4 0.72 9.1 3.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2946 PF11162.3 EME30096.1 - 0.95 9.6 6.0 1.6 8.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) BAF1_ABF1 PF04684.8 EME30096.1 - 0.98 8.1 16.1 1.3 7.7 11.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fringe PF02434.11 EME30097.1 - 6.8e-24 84.4 0.0 9.6e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EME30097.1 - 3.5e-09 36.5 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.1 EME30097.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 NKAIN PF05640.9 EME30097.1 - 0.15 10.9 0.9 0.24 10.3 0.6 1.3 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein CPSase_L_D2 PF02786.12 EME30098.1 - 1.2e-70 237.1 0.0 3.2e-69 232.4 0.0 2.4 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME30098.1 - 3e-41 139.9 0.0 6.3e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME30098.1 - 1.2e-31 108.8 0.0 2.4e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EME30098.1 - 4.6e-16 58.2 0.2 2.1e-15 56.1 0.1 2.3 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EME30098.1 - 3.8e-14 52.8 0.0 8.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EME30098.1 - 1.9e-12 46.6 0.0 2.6e-09 36.5 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 EME30098.1 - 3e-11 42.6 0.0 8e-11 41.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EME30098.1 - 3e-07 30.0 0.0 6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EME30098.1 - 3.4e-07 29.7 0.0 7.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EME30098.1 - 0.00015 22.0 0.1 0.34 11.2 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EME30098.1 - 0.0011 18.4 0.0 0.0078 15.5 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 EME30098.1 - 0.0057 16.3 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EME30098.1 - 0.0066 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein GARS_A PF01071.14 EME30098.1 - 0.045 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EME30098.1 - 0.081 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF2443 PF10398.4 EME30099.1 - 0.012 15.4 2.5 0.021 14.5 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) BEX PF04538.7 EME30099.1 - 0.11 12.7 6.9 0.9 9.7 2.4 2.2 1 1 0 2 2 2 0 Brain expressed X-linked like family Imm42 PF15601.1 EME30099.1 - 0.11 11.9 1.2 0.13 11.7 0.9 1.1 1 0 0 1 1 1 0 Immunity protein 42 DUF2205 PF10224.4 EME30099.1 - 0.13 11.8 8.6 0.2 11.2 5.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) PspA_IM30 PF04012.7 EME30099.1 - 0.42 9.9 11.3 0.52 9.6 7.9 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF3573 PF12097.3 EME30099.1 - 0.43 9.1 2.2 0.47 9.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2951 PF11166.3 EME30099.1 - 0.52 10.1 7.2 0.88 9.4 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) IncA PF04156.9 EME30099.1 - 0.55 9.7 9.7 0.66 9.5 6.8 1.2 1 0 0 1 1 1 0 IncA protein LCD1 PF09798.4 EME30099.1 - 0.64 7.9 9.9 0.66 7.8 6.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF722 PF05263.6 EME30099.1 - 1.7 8.8 5.5 2.1 8.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF722) DUF2681 PF10883.3 EME30099.1 - 1.8 8.8 10.7 2.8 8.1 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Ammonium_transp PF00909.16 EME30100.1 - 1.8e-113 379.0 26.3 2.4e-113 378.6 18.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family p450 PF00067.17 EME30101.1 - 1.1e-76 258.2 0.2 1.5e-76 257.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EME30102.1 - 1.4e-10 41.2 0.0 1.6e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME30102.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME30102.1 - 0.00025 20.9 0.0 0.0003 20.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EME30102.1 - 0.0011 17.9 0.0 0.0012 17.7 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 EME30102.1 - 0.011 15.4 0.2 0.018 14.8 0.1 1.4 1 1 0 1 1 1 0 ThiF family Epimerase PF01370.16 EME30102.1 - 0.021 14.2 0.0 0.026 13.9 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME30102.1 - 0.045 12.4 0.0 0.054 12.1 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EME30103.1 - 5.2e-25 88.2 0.0 6.4e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME30103.1 - 9e-23 81.2 0.0 1.1e-22 81.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME30103.1 - 6.7e-07 29.1 0.0 3.5e-06 26.7 0.0 1.8 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME30103.1 - 0.009 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 EME30103.1 - 0.033 14.0 0.3 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 ThiF family Epimerase PF01370.16 EME30103.1 - 0.038 13.4 0.0 0.049 13.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UQ_con PF00179.21 EME30104.1 - 8.7e-36 122.4 0.0 1.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HALZ PF02183.13 EME30105.1 - 0.0024 17.5 4.1 0.0024 17.5 2.8 4.2 2 1 2 4 4 4 1 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EME30105.1 - 0.016 14.3 4.5 0.031 13.4 3.1 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EME30105.1 - 0.18 11.6 13.3 0.049 13.4 4.3 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2316 PF10078.4 EME30105.1 - 0.31 11.0 6.4 0.36 10.8 1.2 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) TBPIP PF07106.8 EME30105.1 - 0.7 9.4 49.4 0.14 11.6 6.3 4.2 3 1 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0118 PF01594.11 EME30105.1 - 0.8 8.6 1.4 1.5 7.7 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF4055 PF13264.1 EME30105.1 - 1.5 8.9 15.6 2 8.5 0.8 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4055) DASH_Dam1 PF08653.5 EME30105.1 - 2 8.2 12.0 0.16 11.7 0.6 4.0 4 1 1 5 5 5 0 DASH complex subunit Dam1 DUF1664 PF07889.7 EME30105.1 - 3.5 7.4 19.1 1.2 8.9 6.6 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 EME30105.1 - 3.6 6.7 39.1 0.3 10.3 3.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) IncA PF04156.9 EME30105.1 - 3.8 7.0 59.2 0.066 12.8 14.6 4.0 3 2 1 4 4 4 0 IncA protein ADIP PF11559.3 EME30105.1 - 6.3 6.6 50.8 0.017 15.0 9.5 4.1 4 1 0 4 4 3 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 EME30105.1 - 6.9 6.0 31.7 9.6 5.5 0.5 4.5 3 2 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) RRM_1 PF00076.17 EME30106.1 - 1.4e-49 165.5 0.0 3.1e-17 61.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30106.1 - 3.5e-35 119.8 0.0 2.5e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30106.1 - 1.4e-26 92.1 0.0 1.4e-08 34.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VEFS-Box PF09733.4 EME30107.1 - 2.7e-29 101.6 1.6 7.5e-29 100.1 1.1 1.8 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Spc97_Spc98 PF04130.8 EME30108.1 - 6.3e-98 328.4 13.3 1.1e-97 327.6 9.2 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Cytochrom_NNT PF03264.9 EME30108.1 - 0.028 13.8 0.1 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region GET2 PF08690.5 EME30108.1 - 1.2 8.3 8.5 3.3 6.8 5.9 1.7 1 1 0 1 1 1 0 GET complex subunit GET2 ATP-grasp_4 PF13535.1 EME30109.1 - 1e-43 149.2 0.0 1.7e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME30109.1 - 3.3e-18 65.5 0.0 7.6e-18 64.3 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EME30109.1 - 6.3e-12 45.6 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EME30109.1 - 1.9e-07 30.7 0.0 5e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EME30109.1 - 0.00033 20.0 0.0 0.00078 18.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME30109.1 - 0.00091 18.6 0.0 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EME30109.1 - 0.023 13.9 0.0 0.17 11.1 0.0 2.2 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 EME30109.1 - 0.058 12.9 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain BHD_3 PF10405.4 EME30110.1 - 6.8e-23 80.1 0.0 1.2e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EME30110.1 - 2.4e-16 58.9 0.4 4.9e-16 58.0 0.3 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EME30110.1 - 4.9e-10 39.5 0.2 1.7e-09 37.8 0.1 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 EME30110.1 - 5.6e-10 38.7 3.2 5.6e-10 38.7 2.2 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain CTD_bind PF04818.8 EME30110.1 - 0.043 14.0 0.2 0.4 10.9 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. BHD_3 PF10405.4 EME30111.1 - 7.4e-23 80.0 0.0 1.4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EME30111.1 - 2.7e-16 58.8 0.4 5.4e-16 57.8 0.3 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EME30111.1 - 5e-10 39.5 0.2 1.9e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 EME30111.1 - 6.4e-10 38.5 3.2 6.4e-10 38.5 2.2 2.4 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain CTD_bind PF04818.8 EME30111.1 - 0.052 13.8 0.2 0.45 10.8 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase II-binding domain. COX5B PF01215.14 EME30112.1 - 6.4e-20 71.2 0.0 8.8e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 EME30112.1 - 0.00088 19.0 0.4 0.0015 18.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain Rad50_zn_hook PF04423.9 EME30112.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Phosphoesterase PF04185.9 EME30113.1 - 1.1e-22 80.7 12.5 4.3e-14 52.5 1.1 2.6 2 1 1 3 3 3 2 Phosphoesterase family Aminotran_1_2 PF00155.16 EME30114.1 - 1.3e-55 188.8 0.0 4.1e-55 187.2 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME30114.1 - 3e-07 29.8 0.0 6.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EME30114.1 - 0.0049 15.6 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.27 EME30115.1 - 1.1e-12 47.3 2.0 0.0065 16.3 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME30115.1 - 0.067 11.4 0.0 0.12 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain zf-PARP PF00645.13 EME30115.1 - 0.1 12.8 0.1 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Peptidase_S9 PF00326.16 EME30116.1 - 1.4e-21 76.7 0.0 3.4e-21 75.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EME30116.1 - 9.4e-07 28.5 0.0 5e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EME30116.1 - 5.5e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME30116.1 - 0.00054 19.9 0.1 0.0052 16.7 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME30116.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EME30116.1 - 0.11 11.9 0.5 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative esterase RNA_pol_Rpc4 PF05132.9 EME30117.1 - 0.05 13.5 0.5 0.05 13.5 0.3 3.4 3 1 0 3 3 3 0 RNA polymerase III RPC4 FNIP_N PF14636.1 EME30117.1 - 2.3 8.6 9.5 0.49 10.8 3.5 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Asp-B-Hydro_N PF05279.6 EME30117.1 - 3.9 7.2 10.7 2.2 8.0 2.7 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region NapB PF03892.9 EME30117.1 - 8.9 5.9 9.3 0.37 10.4 1.5 2.1 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) MRL1 PF13003.2 EME30118.1 - 1.6 8.5 6.5 0.37 10.6 1.3 2.2 2 1 1 3 3 3 0 Ribosomal protein L1 GARS_A PF01071.14 EME30119.1 - 5.5e-81 270.7 0.0 8e-81 270.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EME30119.1 - 5.3e-33 113.4 0.1 1.5e-32 112.0 0.1 1.8 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EME30119.1 - 5.9e-28 96.8 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EME30119.1 - 3.3e-15 56.3 0.0 9.3e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME30119.1 - 2.1e-06 26.7 0.0 6.4e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EME30119.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EME30119.1 - 0.00026 20.3 0.0 0.0006 19.1 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EME30119.1 - 0.00049 19.6 0.0 0.00095 18.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EME30119.1 - 0.00068 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Phage_int_SAM_1 PF02899.12 EME30119.1 - 0.0026 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Dala_Dala_lig_C PF07478.8 EME30119.1 - 0.0033 16.8 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus dTMP_synthase PF02593.9 EME30119.1 - 0.0042 16.4 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Thymidylate synthase GCV_T PF01571.16 EME30120.1 - 1.4e-12 47.4 0.0 2.7e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME30120.1 - 9.9e-06 25.4 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Sugar_tr PF00083.19 EME30121.1 - 1e-25 90.2 33.5 1.2e-23 83.3 23.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30121.1 - 1.3e-14 53.7 40.1 8.7e-09 34.5 10.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ERG2_Sigma1R PF04622.7 EME30122.1 - 8.5e-57 191.8 1.4 1.1e-56 191.5 1.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3149 PF11346.3 EME30122.1 - 0.081 12.4 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Elf1 PF05129.8 EME30123.1 - 1.6e-29 101.4 2.8 1.7e-29 101.2 2.0 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 EME30123.1 - 6.9e-06 26.2 1.5 9.3e-06 25.8 1.0 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar Cys_rich_CPXG PF14255.1 EME30123.1 - 0.0011 18.7 2.0 0.0017 18.1 1.4 1.3 1 0 0 1 1 1 1 Cysteine-rich CPXCG zf-CHY PF05495.7 EME30123.1 - 0.005 16.9 0.8 0.0056 16.7 0.5 1.1 1 0 0 1 1 1 1 CHY zinc finger Rubredoxin PF00301.15 EME30123.1 - 0.035 13.9 1.2 5.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin TerY-C PF15616.1 EME30123.1 - 0.043 13.7 0.6 0.048 13.6 0.4 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain C1_4 PF07975.7 EME30123.1 - 0.082 12.9 3.6 0.27 11.2 0.3 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EME30123.1 - 0.1 12.5 2.4 0.18 11.7 1.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EME30123.1 - 0.12 11.9 2.0 0.48 10.0 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PhnA_Zn_Ribbon PF08274.7 EME30123.1 - 0.18 11.6 1.6 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-Di19 PF05605.7 EME30123.1 - 0.52 10.4 6.5 7.5 6.7 4.5 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 EME30123.1 - 1.1 9.0 4.4 2.1 8.2 3.0 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RRM_1 PF00076.17 EME30124.1 - 5.9e-63 208.4 3.9 1.4e-19 69.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30124.1 - 4.4e-51 170.7 0.8 1.2e-16 60.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30124.1 - 1.1e-41 140.5 0.3 4.9e-11 42.3 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0122 PF04297.9 EME30124.1 - 0.0049 16.8 0.1 0.019 14.9 0.1 2.0 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Membralin PF09746.4 EME30124.1 - 5.2 6.0 7.6 6.7 5.6 2.8 2.4 2 0 0 2 2 2 0 Tumour-associated protein Mpv17_PMP22 PF04117.7 EME30125.1 - 4.6e-24 83.8 2.7 4.6e-24 83.8 1.8 1.8 1 1 1 2 2 2 1 Mpv17 / PMP22 family Cyclase PF04199.8 EME30126.1 - 9.6e-12 44.9 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Kinesin PF00225.18 EME30127.1 - 4.5e-115 383.9 0.2 4.5e-115 383.9 0.2 3.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EME30127.1 - 0.00022 21.3 0.0 0.00022 21.3 0.0 6.4 2 1 2 5 5 5 1 Kinesin-associated microtubule-binding Kinesin PF00225.18 EME30128.1 - 4.9e-115 383.8 0.2 4.9e-115 383.8 0.2 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.1 EME30128.1 - 9e-05 22.6 0.7 9e-05 22.6 0.5 6.3 2 1 2 5 5 5 1 Kinesin-associated microtubule-binding Sec20 PF03908.8 EME30129.1 - 1.7e-09 37.2 5.0 1.7e-09 37.2 3.4 2.9 2 0 0 2 2 2 1 Sec20 Sec20 PF03908.8 EME30130.1 - 1.4e-07 31.1 4.5 1.4e-07 31.1 3.1 2.9 2 0 0 2 2 2 1 Sec20 XhlA PF10779.4 EME30130.1 - 0.031 14.1 0.8 0.031 14.1 0.5 4.2 3 1 1 4 4 4 0 Haemolysin XhlA PCI_Csn8 PF10075.4 EME30131.1 - 3.3e-20 72.3 0.0 5.3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EME30131.1 - 6.3e-18 65.0 0.1 8.5e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EME30131.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain WD40 PF00400.27 EME30132.1 - 8.6e-19 66.6 9.4 9.1e-06 25.3 0.5 4.6 4 1 1 5 5 5 4 WD domain, G-beta repeat DUF3172 PF11371.3 EME30132.1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) PQQ PF01011.16 EME30132.1 - 0.14 11.7 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat WD40 PF00400.27 EME30133.1 - 7.7e-17 60.4 9.1 6.8e-06 25.7 0.5 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3172 PF11371.3 EME30133.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) PQQ PF01011.16 EME30133.1 - 0.11 12.0 0.0 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat Peptidase_M24 PF00557.19 EME30134.1 - 8.8e-41 139.7 0.0 1.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EME30134.1 - 1.1e-27 97.1 0.0 9.7e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain FANCL_C PF11793.3 EME30134.1 - 0.023 14.6 1.1 0.11 12.5 0.3 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain 3HCDH_N PF02737.13 EME30135.1 - 1.3e-54 184.6 3.2 1.7e-54 184.2 2.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EME30135.1 - 3e-16 59.5 0.0 1.1e-15 57.7 0.0 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EME30135.1 - 9.8e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME30135.1 - 0.00043 20.1 1.3 0.00043 20.1 0.9 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME30135.1 - 0.00067 19.4 3.2 0.00095 18.9 0.7 2.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EME30135.1 - 0.0018 17.7 0.4 0.056 12.8 0.1 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EME30135.1 - 0.0048 17.3 1.2 0.016 15.6 0.2 2.3 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME30135.1 - 0.012 15.6 1.8 0.059 13.3 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain Methyltransf_12 PF08242.7 EME30135.1 - 0.033 14.6 0.1 0.11 12.9 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 EME30135.1 - 0.04 13.9 0.6 0.85 9.6 0.4 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME30135.1 - 0.041 12.7 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase bPH_2 PF03703.9 EME30135.1 - 0.18 11.8 0.8 14 5.8 0.0 3.7 3 1 1 4 4 4 0 Bacterial PH domain ParA PF10609.4 EME30136.1 - 4.9e-37 125.6 0.3 1.8e-36 123.8 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EME30136.1 - 1.4e-18 66.9 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME30136.1 - 1.5e-07 31.4 0.0 6.7e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME30136.1 - 2.4e-06 27.0 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EME30136.1 - 5.7e-06 25.5 0.0 2.3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EME30136.1 - 7.1e-05 21.9 0.4 0.0002 20.4 0.1 1.8 1 1 1 2 2 2 1 Anion-transporting ATPase NACHT PF05729.7 EME30136.1 - 0.005 16.5 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EME30136.1 - 0.0061 17.3 0.1 0.017 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EME30136.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 EME30136.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 EME30136.1 - 0.034 13.0 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 EME30136.1 - 0.044 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EME30136.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EME30136.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EME30136.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EME30136.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 EME30136.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 EME30136.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_C12 PF01088.16 EME30137.1 - 0.048 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Proteasome PF00227.21 EME30137.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit YvrJ PF12841.2 EME30137.1 - 0.13 11.6 0.4 0.23 10.7 0.3 1.4 1 0 0 1 1 1 0 YvrJ protein family DnaJ_CXXCXGXG PF00684.14 EME30137.1 - 0.61 10.1 9.8 2 8.5 6.8 2.0 1 1 0 1 1 1 0 DnaJ central domain Proteasome PF00227.21 EME30138.1 - 0.004 16.4 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Peptidase_C12 PF01088.16 EME30138.1 - 0.055 12.6 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 YvrJ PF12841.2 EME30138.1 - 0.12 11.6 0.4 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 YvrJ protein family AIG2 PF06094.7 EME30139.1 - 7.1e-15 55.3 0.0 1.7e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EME30139.1 - 0.0024 17.9 0.1 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family IU_nuc_hydro PF01156.14 EME30140.1 - 1.5e-95 320.0 0.0 1.8e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyoxalase_4 PF13669.1 EME30141.1 - 4.2e-17 62.1 0.0 6.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME30141.1 - 3.5e-10 40.4 0.0 5.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME30141.1 - 6.2e-10 39.1 0.0 8.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EME30141.1 - 1.2e-07 31.8 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain DEAD PF00270.24 EME30142.1 - 6.4e-20 71.3 0.0 1.7e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase TRCF PF03461.10 EME30142.1 - 7.7e-17 61.1 0.0 2.2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 TRCF domain CarD_CdnL_TRCF PF02559.11 EME30142.1 - 7.9e-15 54.6 0.1 2e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain Helicase_C PF00271.26 EME30142.1 - 1.2e-12 47.5 0.2 8e-11 41.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME30142.1 - 9e-06 25.6 0.0 2.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EME30142.1 - 0.021 14.5 0.0 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain UCR_hinge PF02320.11 EME30143.1 - 2e-24 85.2 5.2 2.3e-24 85.1 3.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EME30143.1 - 0.015 15.1 6.2 0.095 12.5 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) CHCH PF06747.8 EME30143.1 - 0.4 10.6 6.3 0.35 10.8 0.6 2.3 2 0 0 2 2 2 0 CHCH domain Crust_neurohorm PF01147.12 EME30143.1 - 0.46 9.8 3.2 0.38 10.0 0.4 1.9 1 1 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family COX6B PF02297.12 EME30143.1 - 2.2 8.3 9.1 0.96 9.5 0.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Fasciclin PF02469.17 EME30144.1 - 6.7e-10 39.0 0.0 9.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain CM2 PF03021.9 EME30144.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein Glyco_transf_25 PF01755.12 EME30145.1 - 2.3e-21 76.3 0.3 5.7e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Fringe PF02434.11 EME30145.1 - 1.1e-05 24.7 0.1 4e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Glyco_transf_21 PF13506.1 EME30145.1 - 0.0089 15.3 0.0 0.94 8.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME30145.1 - 0.022 14.4 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 zf-LSD1 PF06943.7 EME30146.1 - 0.00014 21.3 3.1 0.00014 21.3 2.2 4.4 4 2 1 5 5 5 2 LSD1 zinc finger IBR PF01485.16 EME30146.1 - 0.0015 18.3 7.3 0.73 9.7 0.4 3.2 3 0 0 3 3 3 2 IBR domain Ribosomal_S27e PF01667.12 EME30146.1 - 0.02 14.3 1.2 0.02 14.3 0.9 3.4 3 0 0 3 3 3 0 Ribosomal protein S27 HypA PF01155.14 EME30146.1 - 0.066 12.9 5.7 1.2 8.8 0.1 3.0 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_5 PF13719.1 EME30146.1 - 0.14 11.7 8.8 6.3 6.4 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF2769 PF10967.3 EME30146.1 - 0.28 11.5 5.5 11 6.3 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2769) zinc_ribbon_4 PF13717.1 EME30146.1 - 0.34 10.6 9.4 8.2 6.2 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 EME30146.1 - 0.52 10.1 7.3 0.11 12.3 1.6 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e DUF3133 PF11331.3 EME30146.1 - 0.68 9.5 19.4 3.1 7.4 0.2 4.4 3 2 0 3 3 3 0 Protein of unknown function (DUF3133) GFA PF04828.9 EME30146.1 - 1.1 9.2 11.6 1.3 9.0 0.3 4.0 1 1 3 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 EME30146.1 - 1.7 8.9 12.4 3.3 8.0 2.5 3.8 2 2 0 2 2 2 0 Restriction alleviation protein Lar CRCB PF02537.10 EME30147.1 - 3.5e-28 97.8 20.3 3.1e-15 56.0 3.2 2.9 4 0 0 4 4 4 2 CrcB-like protein eIF-1a PF01176.14 EME30148.1 - 5.2e-24 83.4 0.2 8.4e-24 82.7 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 S1 PF00575.18 EME30148.1 - 0.031 14.3 0.7 0.072 13.1 0.5 1.6 1 1 0 1 1 1 0 S1 RNA binding domain TPR_12 PF13424.1 EME30149.1 - 2.3e-11 43.4 4.2 0.0033 17.3 0.0 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME30149.1 - 1e-05 25.0 4.1 6.1 7.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME30149.1 - 0.0082 16.2 0.2 74 3.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME30149.1 - 0.014 15.3 5.8 9.8 6.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME30149.1 - 0.015 15.0 4.0 12 5.9 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME30149.1 - 0.015 14.8 4.2 25 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EME30149.1 - 0.024 14.7 0.9 0.066 13.3 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EME30149.1 - 0.35 10.5 5.1 7 6.3 0.3 3.4 2 2 0 2 2 2 0 TPR repeat TPR_6 PF13174.1 EME30149.1 - 1.8 9.1 4.6 8.6 7.0 0.3 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat CTP_transf_1 PF01148.15 EME30150.1 - 4.2e-07 29.9 12.7 1e-06 28.6 8.3 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family Dispanin PF04505.7 EME30150.1 - 0.036 13.5 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Interferon-induced transmembrane protein TraX PF05857.6 EME30150.1 - 5.4 6.6 10.2 0.94 9.0 0.8 2.8 1 1 0 2 2 2 0 TraX protein Chloroa_b-bind PF00504.16 EME30151.1 - 4e-10 40.1 0.5 9.3e-05 22.7 0.0 1.4 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Peptidase_C12 PF01088.16 EME30152.1 - 5.6e-68 228.3 0.0 8.9e-68 227.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 GDPD PF03009.12 EME30153.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-CCHC_4 PF14392.1 EME30154.1 - 0.007 16.0 4.8 0.074 12.7 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EME30154.1 - 0.0075 16.2 14.7 0.13 12.3 5.2 2.5 2 0 0 2 2 2 2 DnaJ central domain zf-CCHC PF00098.18 EME30154.1 - 0.047 13.6 2.1 0.047 13.6 1.5 3.7 3 0 0 3 3 3 0 Zinc knuckle EMI PF07546.8 EME30154.1 - 0.053 13.9 3.4 0.053 13.9 2.4 2.5 2 1 0 2 2 2 0 EMI domain Ribosomal_L23 PF00276.15 EME30155.1 - 1e-08 35.0 0.4 1.7e-08 34.2 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 VPS11_C PF12451.3 EME30156.1 - 7e-06 25.7 0.6 1.7e-05 24.5 0.4 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Vps39_2 PF10367.4 EME30156.1 - 0.0036 17.4 0.8 0.054 13.6 0.1 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EME30156.1 - 0.032 14.0 2.3 0.15 11.9 1.6 2.3 1 0 0 1 1 1 0 Ring finger domain Tektin PF03148.9 EME30156.1 - 0.043 12.3 1.5 2.2 6.7 0.8 2.3 2 0 0 2 2 2 0 Tektin family zf-C3HC4_2 PF13923.1 EME30156.1 - 1.8 8.6 11.7 0.44 10.6 1.0 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30156.1 - 2.3 8.0 8.1 0.2 11.4 1.2 2.7 2 0 0 2 2 2 0 zinc-RING finger domain EF-hand_1 PF00036.27 EME30157.1 - 2.3e-06 26.5 0.1 1.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EME30157.1 - 4.3e-06 26.1 0.6 0.00017 21.1 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EME30157.1 - 1.9e-05 24.7 0.4 2.4e-05 24.3 0.3 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EME30157.1 - 0.0079 15.4 0.1 0.0079 15.4 0.0 2.3 3 0 0 3 3 3 1 EF hand APC2 PF08672.6 EME30157.1 - 0.07 13.3 0.1 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 EF-hand_8 PF13833.1 EME30157.1 - 0.094 12.3 1.9 2.9 7.6 0.7 3.0 1 1 1 2 2 2 0 EF-hand domain pair DUF2036 PF09724.4 EME30158.1 - 5.2e-43 147.4 0.1 7e-43 146.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DAHP_synth_1 PF00793.15 EME30158.1 - 5.4e-22 77.7 0.0 8.8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family DAHP_synth_1 PF00793.15 EME30159.1 - 4.1e-64 215.8 0.0 6.5e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family DUF2036 PF09724.4 EME30159.1 - 1.1e-42 146.3 0.1 1.8e-42 145.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) GST_C_2 PF13410.1 EME30160.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME30160.1 - 0.00021 21.7 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EME30160.1 - 0.00021 21.1 0.0 0.17 11.7 0.0 2.3 1 1 1 2 2 2 2 Tom37 C-terminal domain Tom37 PF10568.4 EME30160.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein CTC1_2 PF15491.1 EME30160.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 VP_N-CPKC PF11475.3 EME30160.1 - 0.16 11.5 0.4 0.31 10.6 0.3 1.4 1 0 0 1 1 1 0 Virion protein N terminal domain SAPS PF04499.10 EME30161.1 - 1.2e-05 24.2 6.9 1.5e-05 23.8 0.0 3.0 2 1 1 3 3 3 1 SIT4 phosphatase-associated protein Spc97_Spc98 PF04130.8 EME30162.1 - 4.6e-111 371.7 9.1 4.6e-111 371.7 6.3 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family WD40 PF00400.27 EME30163.1 - 1.3e-09 37.5 9.7 9.9e-07 28.4 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Semialdhyde_dh PF01118.19 EME30164.1 - 3.5e-27 95.1 0.0 6.4e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 EME30164.1 - 1.1e-19 71.0 0.0 1.8e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 EME30164.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF498 PF04430.9 EME30165.1 - 6.7e-21 73.9 0.0 8.1e-21 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF498 PF04430.9 EME30166.1 - 1.3e-11 43.9 0.0 3e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) HTH_11 PF08279.7 EME30166.1 - 0.097 12.3 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 HTH domain GST_N_3 PF13417.1 EME30168.1 - 1.4e-17 63.7 0.1 3.5e-16 59.1 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME30168.1 - 7.4e-16 57.9 0.1 5.8e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME30168.1 - 1.6e-06 28.1 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME30168.1 - 1.3e-05 24.9 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME30168.1 - 1.8e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME30168.1 - 0.00042 20.2 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L30 PF00327.15 EME30169.1 - 1.6e-21 75.6 1.2 4.5e-21 74.1 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EME30169.1 - 2.5e-20 72.2 24.9 4.9e-20 71.3 17.3 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain OmpH PF03938.9 EME30169.1 - 0.052 13.4 5.8 0.078 12.9 4.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cast PF10174.4 EME30170.1 - 0.00066 17.8 0.8 0.0007 17.7 0.5 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF1635 PF07795.6 EME30170.1 - 0.067 12.5 0.3 0.071 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RloB PF13707.1 EME30170.1 - 0.13 11.9 0.7 0.15 11.7 0.5 1.1 1 0 0 1 1 1 0 RloB-like protein S-methyl_trans PF02574.11 EME30171.1 - 7e-66 222.6 0.0 9.2e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase GFO_IDH_MocA PF01408.17 EME30172.1 - 1.5e-30 106.2 1.1 5.4e-30 104.3 0.4 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME30172.1 - 1.1e-10 41.3 0.0 2.5e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain TrkA_N PF02254.13 EME30172.1 - 0.00038 20.4 0.3 0.0016 18.3 0.0 2.1 2 1 1 3 3 3 1 TrkA-N domain Semialdhyde_dh PF01118.19 EME30172.1 - 0.0067 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME30172.1 - 0.053 13.9 0.2 0.24 11.8 0.0 2.1 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PRTP PF01366.13 EME30172.1 - 0.058 11.3 0.0 0.081 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein NAD_binding_7 PF13241.1 EME30172.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 EME30172.1 - 0.11 11.4 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase AIRS_C PF02769.17 EME30174.1 - 1.5e-20 73.7 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME30174.1 - 3.8e-08 33.4 0.0 7.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2505 PF10698.4 EME30175.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) adh_short PF00106.20 EME30176.1 - 7e-31 107.3 1.0 8.8e-31 107.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME30176.1 - 5.5e-27 95.0 1.0 1e-26 94.2 0.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME30176.1 - 1.5e-10 41.0 0.2 2.2e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME30176.1 - 1.7e-07 30.9 0.9 3.3e-07 29.9 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME30176.1 - 1.8e-06 27.0 1.4 2.1e-06 26.8 0.2 1.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EME30176.1 - 0.00083 19.0 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME30176.1 - 0.045 13.7 0.8 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 EME30176.1 - 0.052 13.5 0.4 0.068 13.1 0.2 1.5 1 1 0 1 1 1 0 NADH(P)-binding Glyco_hydro_15 PF00723.16 EME30177.1 - 1.9e-45 155.2 0.0 2.4e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.16 EME30178.1 - 1.6e-42 145.6 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.16 EME30179.1 - 1e-43 149.5 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 IF-2B PF01008.12 EME30180.1 - 4.4e-55 186.6 0.0 6e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med31 PF05669.7 EME30181.1 - 2.1e-29 101.2 5.8 2.4e-29 101.0 4.0 1.0 1 0 0 1 1 1 1 SOH1 Med31 PF05669.7 EME30182.1 - 1.1e-29 102.2 9.6 1.2e-29 102.0 6.7 1.0 1 0 0 1 1 1 1 SOH1 DUF647 PF04884.9 EME30183.1 - 2.6e-63 213.5 0.1 4.3e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1997 PF09366.5 EME30184.1 - 0.0023 17.7 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF1447 PF07288.6 EME30184.1 - 0.015 15.0 0.2 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) CTDII PF01556.13 EME30186.1 - 1.3e-35 121.0 2.7 1.1e-24 86.0 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EME30186.1 - 2.3e-27 94.4 1.5 3.8e-27 93.7 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EME30186.1 - 1.1e-15 57.4 20.6 1.2e-15 57.2 11.0 2.4 2 0 0 2 2 2 1 DnaJ central domain DZR PF12773.2 EME30186.1 - 1.5 8.7 17.0 1.7 8.5 8.4 2.9 2 1 0 2 2 2 0 Double zinc ribbon FdhE PF04216.7 EME30186.1 - 1.6 8.3 11.0 14 5.3 0.0 2.7 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation CP12 PF02672.10 EME30187.1 - 1.9e-28 98.7 7.2 2.6e-28 98.2 5.0 1.2 1 0 0 1 1 1 1 CP12 domain Abhydrolase_6 PF12697.2 EME30188.1 - 2.4e-10 40.6 0.0 4.2e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME30188.1 - 8.3e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EME30188.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME30188.1 - 0.012 15.2 0.0 0.033 13.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold zf-MYND PF01753.13 EME30189.1 - 2e-09 37.1 15.5 5.8e-09 35.6 10.8 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EME30189.1 - 1.1 9.2 12.3 0.25 11.2 5.8 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_jaz PF12171.3 EME30190.1 - 1.1e-09 38.1 1.9 1.8e-09 37.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME30190.1 - 0.00014 21.9 0.5 0.00022 21.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EME30190.1 - 0.0023 17.9 0.1 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EME30190.1 - 0.029 13.9 1.5 0.055 13.0 1.1 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 EME30190.1 - 0.063 13.6 1.9 0.11 12.9 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Wbp11 PF09429.5 EME30190.1 - 0.43 10.5 3.8 1.1 9.2 1.3 2.0 2 0 0 2 2 2 0 WW domain binding protein 11 DUF674 PF05056.7 EME30192.1 - 0.034 12.7 0.1 0.034 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Sugar_tr PF00083.19 EME30197.1 - 2.4e-31 108.8 27.3 7.4e-18 64.3 5.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME30197.1 - 8.4e-15 54.3 30.4 1.1e-11 44.0 21.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EME30197.1 - 0.39 9.3 8.0 0.89 8.1 0.0 3.1 3 0 0 3 3 3 0 BT1 family Topoisom_bac PF01131.15 EME30198.1 - 1.2e-93 314.1 0.0 1.4e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EME30198.1 - 6.9e-15 54.8 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF1882 PF08966.6 EME30198.1 - 0.012 15.5 0.0 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) HypA PF01155.14 EME30198.1 - 2.4 7.8 10.7 4.1 7.1 0.8 3.3 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Cna_B PF05738.8 EME30199.1 - 0.012 15.3 0.4 0.041 13.6 0.3 2.0 1 0 0 1 1 1 0 Cna protein B-type domain AA_permease_2 PF13520.1 EME30200.1 - 7.9e-38 130.0 21.8 9.8e-38 129.7 15.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME30200.1 - 1.9e-21 76.0 16.0 3.2e-21 75.2 11.1 1.3 1 1 0 1 1 1 1 Amino acid permease Glycos_transf_1 PF00534.15 EME30201.1 - 1.4e-30 105.9 0.0 2.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME30201.1 - 3.4e-14 53.3 0.0 1e-12 48.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EME30201.1 - 1.3e-13 51.2 0.0 3.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME30201.1 - 1.7e-11 44.2 0.0 4.3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME30201.1 - 5.5e-09 35.9 0.5 1.1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 EME30201.1 - 0.00026 20.8 0.0 0.001 18.9 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like Pkinase PF00069.20 EME30202.1 - 3e-63 213.4 0.1 4.2e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30202.1 - 9.2e-29 100.2 0.0 1.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30202.1 - 1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME30202.1 - 0.0019 17.2 0.1 0.004 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME30202.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EME30202.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1962 PF09227.5 EME30202.1 - 0.14 12.2 1.1 0.61 10.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1962) Ins_P5_2-kin PF06090.7 EME30203.1 - 2.2e-25 89.3 0.9 3e-25 88.9 0.6 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase L_biotic_typeA PF04604.8 EME30203.1 - 0.12 11.9 0.9 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Type-A lantibiotic Peptidase_S41 PF03572.13 EME30204.1 - 1.3e-46 158.0 0.1 2.4e-46 157.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.19 EME30204.1 - 1.9e-08 34.3 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EME30204.1 - 2e-05 24.4 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EME30204.1 - 7.8e-05 22.4 0.1 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain Tricorn_C1 PF14684.1 EME30204.1 - 0.00013 21.7 0.6 0.00026 20.7 0.4 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Caveolin PF01146.12 EME30204.1 - 0.073 12.6 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Caveolin CwfJ_C_1 PF04677.10 EME30206.1 - 1.9e-22 79.2 0.0 5.4e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EME30206.1 - 4.8e-06 26.9 0.5 2.7e-05 24.5 0.3 2.1 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 EME30207.1 - 5.7e-68 228.8 0.0 9.6e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30207.1 - 2.3e-31 108.8 0.1 4.6e-31 107.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30207.1 - 5.2e-06 25.6 0.0 7.9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME30207.1 - 0.00077 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME30207.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EME30207.1 - 0.02 14.6 0.2 0.12 12.0 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.20 EME30208.1 - 2.4e-62 210.4 0.0 4.6e-62 209.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30208.1 - 2e-27 95.9 0.2 5.5e-27 94.4 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30208.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like DUF745 PF05335.8 EME30209.1 - 0.16 11.4 1.0 0.22 11.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CHCH PF06747.8 EME30209.1 - 0.74 9.8 3.0 1.4 8.9 2.1 1.5 1 0 0 1 1 1 0 CHCH domain UPF0014 PF03649.8 EME30210.1 - 8.9e-58 195.3 9.4 1.2e-57 194.9 6.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) ABC_tran PF00005.22 EME30210.1 - 3.9e-28 98.4 0.0 5.9e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME30210.1 - 1.4e-06 28.5 0.2 0.001 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME30210.1 - 4.8e-05 23.4 0.2 9.5e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME30210.1 - 7.9e-05 22.8 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EME30210.1 - 0.00033 19.9 0.1 0.067 12.4 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EME30210.1 - 0.012 14.8 0.1 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME30210.1 - 0.02 14.8 0.1 0.25 11.2 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EME30210.1 - 0.036 14.9 0.0 0.062 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EME30210.1 - 0.037 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Arch_ATPase PF01637.13 EME30210.1 - 0.048 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EME30210.1 - 0.055 13.2 0.3 0.34 10.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EME30210.1 - 0.08 12.6 0.1 0.21 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EME30210.1 - 0.092 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME30210.1 - 0.14 11.5 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain NusG PF02357.14 EME30211.1 - 2.1e-13 50.2 1.8 4.7e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Transcription termination factor nusG NDUFA12 PF05071.11 EME30212.1 - 5.4e-17 62.1 1.4 5.4e-17 62.1 1.0 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3991 PF13154.1 EME30212.1 - 0.0021 18.1 0.3 1 9.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3991) DUF4407 PF14362.1 EME30212.1 - 0.11 11.4 0.7 0.12 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_2 PF13923.1 EME30213.1 - 1.3e-09 37.9 11.5 2.9e-09 36.8 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME30213.1 - 4.4e-09 36.0 11.2 1e-08 34.8 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME30213.1 - 2.9e-08 33.2 10.6 5.2e-08 32.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30213.1 - 7.2e-08 31.9 8.2 1.3e-07 31.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PWI PF01480.12 EME30213.1 - 1.9e-06 27.9 0.0 7.6e-06 25.9 0.0 2.0 3 0 0 3 3 2 1 PWI domain zf-RING_5 PF14634.1 EME30213.1 - 5.6e-05 22.7 10.5 0.00013 21.5 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME30213.1 - 0.00031 20.5 10.7 0.00069 19.4 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EME30213.1 - 0.0012 18.7 9.2 0.0036 17.2 6.4 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain GAGA PF09237.6 EME30213.1 - 0.0044 16.5 1.6 0.37 10.4 0.2 2.5 2 0 0 2 2 2 1 GAGA factor zf-Apc11 PF12861.2 EME30213.1 - 0.053 13.3 3.6 0.1 12.4 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HORMA PF02301.13 EME30213.1 - 0.086 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 HORMA domain DUF1644 PF07800.7 EME30213.1 - 0.21 11.4 6.7 0.31 10.8 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING_UBOX PF13445.1 EME30213.1 - 0.24 11.1 8.4 0.72 9.6 5.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EME30213.1 - 0.4 10.2 10.6 0.72 9.4 7.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EME30213.1 - 0.96 9.6 10.0 2.4 8.3 6.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 EME30213.1 - 1.1 9.2 8.3 2.5 8.0 5.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 EME30213.1 - 2.1 7.9 6.9 3.2 7.3 4.3 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EME30213.1 - 2.4 7.8 9.2 5.3 6.7 6.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EME30213.1 - 3.3 7.6 13.3 3.3 7.6 5.7 2.7 1 1 1 2 2 2 0 IBR domain zf-Di19 PF05605.7 EME30213.1 - 5.3 7.2 8.2 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding bZIP_1 PF00170.16 EME30214.1 - 0.0015 18.4 19.0 0.0031 17.4 7.7 2.7 1 1 1 2 2 2 2 bZIP transcription factor V_ATPase_I PF01496.14 EME30214.1 - 0.0017 16.3 5.4 0.0022 15.9 3.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EME30214.1 - 0.12 12.1 19.4 0.057 13.2 7.6 2.7 1 1 1 2 2 2 0 Basic region leucine zipper DUF342 PF03961.8 EME30214.1 - 0.39 9.0 5.0 0.56 8.5 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NYD-SP28_assoc PF14775.1 EME30214.1 - 0.47 10.1 5.4 0.42 10.3 2.0 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_Maf PF03131.12 EME30214.1 - 1.2 9.5 18.0 0.21 11.8 9.5 2.0 2 1 0 2 2 2 0 bZIP Maf transcription factor DUF972 PF06156.8 EME30214.1 - 3.5 8.0 11.1 2 8.8 4.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NAD_Gly3P_dh_C PF07479.9 EME30215.1 - 3.2e-40 137.2 0.2 4.7e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EME30215.1 - 2.8e-37 127.8 0.0 8.4e-21 74.3 0.1 2.7 3 0 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EME30215.1 - 0.0029 17.9 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EME30215.1 - 0.01 16.2 0.2 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EME30215.1 - 0.01 15.4 0.5 0.022 14.4 0.1 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EME30215.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EME30216.1 - 2.8e-42 144.1 0.0 7.5e-42 142.7 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EME30216.1 - 2.9e-40 137.4 0.2 4.3e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EME30216.1 - 0.00022 21.5 0.1 0.00074 19.9 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EME30216.1 - 0.00083 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EME30216.1 - 0.0056 16.3 0.5 0.012 15.2 0.1 1.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EME30216.1 - 0.0093 16.3 0.2 1.3 9.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EME30216.1 - 0.025 13.9 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Myb_DNA-binding PF00249.26 EME30217.1 - 6.8e-12 45.2 0.1 1.4e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fib_alpha PF08702.5 EME30217.1 - 0.018 15.1 2.9 0.031 14.3 1.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Myb_DNA-bind_6 PF13921.1 EME30217.1 - 0.02 14.9 0.1 0.082 13.0 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME30218.1 - 1.9e-29 101.4 7.9 9.1e-15 54.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME30218.1 - 2.5e-26 91.5 4.4 3.6e-17 62.2 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF3102 PF11300.3 EME30218.1 - 0.072 13.1 0.0 13 5.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3102) HTH_7 PF02796.10 EME30218.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Myb_DNA-bind_4 PF13837.1 EME30218.1 - 2.1 8.5 5.8 2.9 8.0 0.3 3.3 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EME30219.1 - 1.1e-09 37.9 0.6 1.9e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 Rap1 Myb domain YqaJ PF09588.5 EME30220.1 - 0.13 12.1 0.0 0.4 10.6 0.0 1.9 1 1 0 1 1 1 0 YqaJ-like viral recombinase domain RF-1 PF00472.15 EME30221.1 - 8.2e-36 122.2 3.8 8.2e-36 122.2 2.7 1.8 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EME30221.1 - 3.5e-23 81.4 0.9 9.4e-23 80.1 0.6 1.8 1 0 0 1 1 1 1 PCRF domain SPOUT_MTase PF02590.12 EME30221.1 - 0.054 13.2 1.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase NAM-associated PF14303.1 EME30221.1 - 0.081 13.2 6.9 0.029 14.6 1.6 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain zf-CCCH_2 PF14608.1 EME30222.1 - 0.0068 16.3 8.2 0.0068 16.3 5.7 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EME30222.1 - 0.044 13.4 4.9 0.11 12.1 3.4 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cas_Csy4 PF09618.5 EME30222.1 - 7.6 6.3 16.6 5.3 6.8 2.5 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) NDUFA12 PF05071.11 EME30223.1 - 4.8e-23 81.6 0.7 6.7e-23 81.1 0.5 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF647 PF04884.9 EME30224.1 - 1.2e-65 221.1 0.4 2.2e-65 220.3 0.3 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DNA_photolyase PF00875.13 EME30224.1 - 1.4e-09 37.8 0.0 3.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Acetyltransf_1 PF00583.19 EME30225.1 - 5.8e-17 61.5 0.0 8.6e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME30225.1 - 1.8e-08 34.4 0.0 2.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME30225.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME30225.1 - 0.00022 21.3 0.1 0.0003 20.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME30225.1 - 0.00029 20.5 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EME30225.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME30225.1 - 0.002 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EME30225.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME30225.1 - 0.033 14.1 0.0 0.084 12.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EME30225.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ENTH PF01417.15 EME30226.1 - 2.1e-41 140.7 0.1 3.5e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EME30226.1 - 0.0015 17.3 0.0 0.0022 16.7 0.0 1.3 1 0 0 1 1 1 1 ANTH domain BH3 PF15285.1 EME30226.1 - 0.15 11.6 0.8 9.4 5.8 0.1 2.8 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting bZIP_1 PF00170.16 EME30227.1 - 0.00013 21.8 5.3 0.00013 21.8 3.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME30227.1 - 0.00018 21.2 9.3 0.00056 19.6 6.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Interfer-bind PF09294.5 EME30227.1 - 0.32 11.0 3.6 4.9 7.2 0.3 2.7 2 1 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Endonuclease_5 PF04493.9 EME30228.1 - 4.8e-47 159.9 0.0 5.9e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 EME30228.1 - 0.036 13.1 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF3143 PF11341.3 EME30228.1 - 0.2 11.5 3.9 0.18 11.7 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) XG_FTase PF03254.8 EME30229.1 - 1.1e-19 70.3 0.0 1.9e-06 26.7 0.0 3.0 3 0 0 3 3 3 3 Xyloglucan fucosyltransferase ABC2_membrane_3 PF12698.2 EME30230.1 - 0.13 11.3 1.5 0.15 11.1 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Glyco_transf_92 PF01697.22 EME30231.1 - 0.02 14.2 0.7 0.032 13.5 0.5 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 92 bZIP_1 PF00170.16 EME30231.1 - 0.021 14.7 11.6 0.05 13.5 8.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 EME30231.1 - 0.66 9.8 11.4 1.3 8.9 7.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper ARID PF01388.16 EME30232.1 - 9.4e-18 63.8 0.0 1.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Arm PF00514.18 EME30232.1 - 0.0022 17.7 0.9 0.025 14.3 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF3518 PF12031.3 EME30232.1 - 0.0065 15.3 0.1 0.22 10.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3518) GTP_EFTU PF00009.22 EME30233.1 - 2.5e-44 150.9 0.0 4.2e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME30233.1 - 1.9e-24 85.7 0.3 1.3e-23 82.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME30233.1 - 8.6e-08 32.1 0.4 2e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME30233.1 - 0.00044 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 EME30233.1 - 0.0039 16.5 0.3 0.0097 15.3 0.2 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF3510 PF12022.3 EME30235.1 - 9.8e-30 103.2 8.1 3.9e-29 101.2 0.1 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3510) DUF4250 PF14056.1 EME30235.1 - 0.033 13.9 0.2 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) ZYG-11_interact PF05884.7 EME30235.1 - 0.16 11.0 0.7 0.28 10.2 0.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 COG2 PF06148.6 EME30235.1 - 0.18 11.6 18.2 0.034 14.0 5.2 3.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 PhoU_div PF01865.11 EME30235.1 - 0.19 10.8 9.0 0.017 14.3 1.0 2.9 3 1 0 3 3 3 0 Protein of unknown function DUF47 TMF_TATA_bd PF12325.3 EME30235.1 - 0.38 10.4 17.1 0.068 12.8 5.7 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Vps51 PF08700.6 EME30235.1 - 1.5 8.7 9.9 1.8 8.4 2.0 3.9 2 1 0 2 2 2 0 Vps51/Vps67 PTEN_C2 PF10409.4 EME30236.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF773 PF05600.7 EME30237.1 - 3.6e-49 167.9 17.4 1.5e-36 126.2 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF773) PRD PF00874.15 EME30237.1 - 0.017 15.2 3.2 0.017 15.2 2.2 3.1 4 0 0 4 4 4 0 PRD domain DUF773 PF05600.7 EME30238.1 - 9.6e-47 159.9 13.3 1.6e-36 126.1 1.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF773) CAAD PF14159.1 EME30239.1 - 6.2e-15 54.6 0.0 1.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase bZIP_Maf PF03131.12 EME30240.1 - 4.9e-05 23.5 10.5 0.00013 22.1 7.3 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EME30240.1 - 0.00038 20.3 16.5 0.0013 18.6 11.4 2.0 1 1 0 1 1 1 1 bZIP transcription factor Kinesin-relat_1 PF12711.2 EME30240.1 - 0.0081 16.5 7.3 0.0081 16.5 5.1 2.7 4 0 0 4 4 4 1 Kinesin motor Fib_alpha PF08702.5 EME30240.1 - 1.7 8.7 7.5 3.8 7.6 5.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.10 EME30240.1 - 7 6.5 18.9 57 3.6 13.1 2.3 1 1 0 1 1 1 0 Basic region leucine zipper SlyX PF04102.7 EME30240.1 - 8.4 6.8 9.4 3.7 8.0 4.2 2.3 2 1 0 2 2 2 0 SlyX dCMP_cyt_deam_1 PF00383.17 EME30241.1 - 1.8e-17 62.8 0.1 2.6e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EME30241.1 - 0.009 15.8 2.3 0.086 12.6 0.4 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase MFS_1 PF07690.11 EME30242.1 - 1.3e-31 109.6 36.7 1.1e-25 90.0 4.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME30242.1 - 2.4e-18 65.9 4.9 2.2e-10 39.7 0.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EME30242.1 - 2.5e-06 26.1 9.6 0.00022 19.7 0.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EME30242.1 - 0.00018 21.2 0.2 0.35 10.7 0.0 2.8 2 0 0 2 2 2 2 MFS_1 like family LRR19-TM PF15176.1 EME30242.1 - 0.19 11.4 0.2 0.73 9.5 0.1 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CIA30 PF08547.7 EME30243.1 - 4.2e-21 75.4 0.1 8.5e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.1 EME30243.1 - 9.9e-21 74.5 0.0 8.4e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EME30243.1 - 5.1e-07 29.1 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EME30243.1 - 2.2e-06 27.3 0.0 9.6e-05 21.9 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EME30243.1 - 0.0092 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EME30243.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EME30243.1 - 0.11 11.1 0.0 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EME30243.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Myb_DNA-bind_6 PF13921.1 EME30244.1 - 1.4e-21 76.3 0.6 8.3e-12 45.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME30244.1 - 3.1e-19 68.7 0.4 3.1e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EME30244.1 - 0.00036 20.3 0.8 0.01 15.7 0.2 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EME30244.1 - 0.0012 18.6 0.1 0.97 9.2 0.0 2.9 2 1 0 2 2 2 2 Rap1 Myb domain R-HINP1I PF11463.3 EME30244.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Myb_DNA-bind_6 PF13921.1 EME30245.1 - 5.9e-20 71.1 0.1 4.4e-12 45.9 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME30245.1 - 1.3e-17 63.5 0.1 2.6e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EME30245.1 - 0.00085 19.0 0.0 0.8 9.5 0.0 2.5 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_5 PF13873.1 EME30245.1 - 0.077 12.9 0.4 3.5 7.5 0.0 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_L18p PF00861.17 EME30248.1 - 4.6e-39 133.2 0.0 4.6e-39 133.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EME30248.1 - 8.9e-32 109.5 5.8 1.8e-31 108.5 4.0 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.1 EME30248.1 - 0.074 11.9 0.7 0.1 11.4 0.5 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA_C PF08546.6 EME30249.1 - 4.9e-05 23.3 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal LINES_N PF14694.1 EME30253.1 - 6.1e-08 32.3 5.4 6.1e-08 32.3 3.8 2.4 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 EME30253.1 - 0.0025 17.0 0.6 0.0053 15.9 0.4 1.6 1 0 0 1 1 1 1 Lines C-terminus GHMP_kinases_N PF00288.21 EME30254.1 - 3.3e-19 68.7 0.2 1.3e-18 66.7 0.2 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME30254.1 - 8.3e-09 35.5 0.1 1.9e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EME30254.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF927 PF06048.6 EME30254.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Malic_M PF03949.10 EME30255.1 - 1.1e-85 287.3 0.0 1.4e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EME30255.1 - 1.7e-70 236.3 0.0 2.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PPR_2 PF13041.1 EME30256.1 - 1.7e-17 63.1 0.9 0.00018 21.4 0.0 7.0 4 2 3 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EME30256.1 - 4.3e-12 45.2 0.1 1.1 9.7 0.0 7.7 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EME30256.1 - 1.6e-08 33.9 1.8 0.15 12.1 0.0 6.2 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 EME30256.1 - 0.00017 20.9 0.0 0.021 14.3 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 EME30257.1 - 8.4e-08 32.0 0.9 0.00028 20.8 0.1 3.3 3 1 0 3 3 3 2 PPR repeat family Clathrin PF00637.15 EME30257.1 - 0.0028 17.2 1.3 0.18 11.3 0.0 3.7 2 2 0 3 3 3 1 Region in Clathrin and VPS PPR_3 PF13812.1 EME30257.1 - 0.0029 17.7 0.4 1.8 9.0 0.0 3.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain DUF98 PF01947.11 EME30257.1 - 0.048 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF98) PPR PF01535.15 EME30257.1 - 0.13 12.3 0.1 6.8 6.9 0.1 3.5 3 0 0 3 3 3 0 PPR repeat Mpv17_PMP22 PF04117.7 EME30258.1 - 6.6e-24 83.3 6.8 1.6e-23 82.0 4.7 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family RICTOR_M PF14666.1 EME30258.1 - 0.059 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain GST_N PF02798.15 EME30259.1 - 6.4e-17 61.4 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME30259.1 - 7.5e-10 38.6 0.1 1.1e-09 38.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME30259.1 - 5.2e-06 26.5 0.0 8.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME30259.1 - 0.00072 19.9 0.0 0.0014 19.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME30259.1 - 0.0071 16.3 0.0 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME30259.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME30260.1 - 1.6e-22 79.3 0.1 1.2e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME30260.1 - 4.1e-13 49.0 0.0 9.9e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME30260.1 - 3.1e-08 33.4 0.0 5.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME30260.1 - 3e-05 24.1 0.0 0.025 14.7 0.0 2.6 1 1 1 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME30260.1 - 0.00012 22.5 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 EME30260.1 - 0.0091 15.5 0.1 0.43 10.1 0.1 2.4 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain NpwBP PF12622.2 EME30260.1 - 0.16 12.4 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 mRNA biogenesis factor ArsA_ATPase PF02374.10 EME30260.1 - 0.17 10.8 0.1 14 4.5 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase GST_N_2 PF13409.1 EME30261.1 - 1.4e-22 79.4 0.1 1.3e-21 76.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME30261.1 - 4.4e-13 48.9 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME30261.1 - 3.2e-08 33.4 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME30261.1 - 3.4e-05 23.9 0.0 0.027 14.6 0.0 2.6 1 1 1 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME30261.1 - 0.00014 22.2 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 EME30261.1 - 0.01 15.4 0.1 0.88 9.1 0.0 2.4 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain NpwBP PF12622.2 EME30261.1 - 0.16 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 mRNA biogenesis factor Metallopep PF12044.3 EME30262.1 - 1.2e-54 185.3 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M66 PF10462.4 EME30262.1 - 0.022 13.6 0.7 0.035 12.9 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 RNA_pol_N PF01194.12 EME30263.1 - 1.8e-30 104.7 2.5 2e-30 104.5 1.7 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EME30263.1 - 0.019 15.0 1.6 0.031 14.3 1.1 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Yippee-Mis18 PF03226.9 EME30263.1 - 0.063 13.3 0.9 0.077 13.0 0.2 1.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DivIC PF04977.10 EME30263.1 - 0.12 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator SEP PF08059.8 EME30264.1 - 2.7e-26 91.6 0.8 3.9e-25 87.9 0.2 2.5 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EME30264.1 - 3.8e-17 62.1 0.0 7.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EME30264.1 - 3.9e-11 42.3 0.0 6.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Clat_adaptor_s PF01217.15 EME30265.1 - 1.7e-38 131.5 0.6 5.5e-34 116.9 0.4 2.5 2 0 0 2 2 2 2 Clathrin adaptor complex small chain FAM47 PF14642.1 EME30265.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 FAM47 family Clat_adaptor_s PF01217.15 EME30266.1 - 6e-19 68.1 0.3 2.5e-14 53.2 0.2 2.5 2 0 0 2 2 2 2 Clathrin adaptor complex small chain FAM47 PF14642.1 EME30266.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 FAM47 family DnaJ_CXXCXGXG PF00684.14 EME30267.1 - 0.0069 16.4 7.8 0.17 11.9 5.5 2.4 1 1 1 2 2 2 2 DnaJ central domain zf-Di19 PF05605.7 EME30267.1 - 0.22 11.6 2.7 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ala_racemase_N PF01168.15 EME30268.1 - 1.9e-25 89.7 0.0 2.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF423 PF04241.10 EME30269.1 - 1.9e-25 88.5 1.8 3.6e-25 87.6 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) tRNA-synt_2b PF00587.20 EME30269.1 - 7.6e-20 71.1 0.0 3.1e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME30269.1 - 2.6e-14 52.9 0.2 4.9e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 EME30269.1 - 5e-12 45.5 0.1 1.2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal CM_2 PF01817.16 EME30270.1 - 5.7e-05 23.1 0.1 0.003 17.6 0.0 3.0 3 1 0 3 3 3 1 Chorismate mutase type II TFIIA_gamma_N PF02268.11 EME30270.1 - 0.12 11.9 0.3 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Sugar_tr PF00083.19 EME30271.1 - 2.2e-29 102.3 32.0 7.1e-28 97.3 22.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30271.1 - 4.1e-18 65.2 58.9 9.5e-14 50.8 21.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME30271.1 - 4e-07 28.7 4.5 4e-07 28.7 3.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein M16C_assoc PF08367.6 EME30272.1 - 1.4e-60 204.2 0.0 2.4e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EME30272.1 - 5.3e-22 78.3 0.0 1.7e-16 60.4 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME30272.1 - 1.1e-07 31.7 0.1 2.2e-06 27.5 0.0 3.1 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) DUF695 PF05117.7 EME30272.1 - 0.096 12.5 0.3 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF695) FF PF01846.14 EME30272.1 - 0.55 10.2 6.3 9.5 6.2 0.0 4.3 4 0 0 4 4 4 0 FF domain G-patch_2 PF12656.2 EME30273.1 - 3.1e-15 55.7 0.1 3.1e-15 55.7 0.1 2.1 2 1 0 2 2 2 1 DExH-box splicing factor binding site Rab_eff_C PF04698.7 EME30273.1 - 0.0072 14.5 0.7 0.0091 14.1 0.5 1.1 1 0 0 1 1 1 1 Rab effector MyRIP/melanophilin C-terminus G-patch PF01585.18 EME30273.1 - 0.017 14.8 3.1 0.05 13.3 2.1 1.8 1 1 0 1 1 1 0 G-patch domain DUF3245 PF11595.3 EME30273.1 - 0.093 12.9 0.0 0.093 12.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3245) Methyltransf_16 PF10294.4 EME30274.1 - 2.7e-13 49.7 0.0 3.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EME30274.1 - 0.036 14.6 0.0 0.051 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 EME30275.1 - 4.6e-21 75.8 0.0 5.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME30275.1 - 8.6e-09 35.0 0.0 1.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BPL_LplA_LipB PF03099.14 EME30276.1 - 2.1e-16 60.0 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB PF03099.14 EME30277.1 - 1.8e-16 60.3 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HSBP1 PF06825.7 EME30278.1 - 7.6e-27 92.6 2.4 1.1e-26 92.1 1.7 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Laminin_I PF06008.9 EME30278.1 - 0.0011 18.3 1.1 0.0012 18.1 0.8 1.0 1 0 0 1 1 1 1 Laminin Domain I Prominin PF05478.6 EME30278.1 - 0.0036 14.9 0.2 0.0036 14.9 0.2 1.0 1 0 0 1 1 1 1 Prominin Erythro-docking PF09277.6 EME30278.1 - 0.0048 16.5 0.1 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 Erythronolide synthase, docking DUF2130 PF09903.4 EME30278.1 - 0.0067 15.2 1.2 0.0083 14.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) CheZ PF04344.8 EME30278.1 - 0.012 15.3 0.4 0.013 15.2 0.3 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ FtsK_SpoIIIE PF01580.13 EME30278.1 - 0.013 14.9 0.2 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2365 PF10157.4 EME30278.1 - 0.021 14.7 0.2 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) GvpK PF05121.7 EME30278.1 - 0.027 14.2 3.4 0.09 12.6 0.1 2.1 1 1 1 2 2 2 0 Gas vesicle protein K phiKZ_IP PF12699.2 EME30278.1 - 0.028 13.3 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins BLOC1_2 PF10046.4 EME30278.1 - 0.035 14.2 1.1 0.084 13.0 0.8 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 EME30278.1 - 0.042 13.6 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EME30278.1 - 0.054 13.2 1.7 0.51 10.1 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4631 PF15450.1 EME30278.1 - 0.054 11.7 1.3 0.061 11.6 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) RRN3 PF05327.6 EME30278.1 - 0.059 11.4 0.2 0.067 11.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Syntaxin PF00804.20 EME30278.1 - 0.068 13.3 3.4 1 9.5 0.8 2.1 1 1 1 2 2 2 0 Syntaxin LOH1CR12 PF10158.4 EME30278.1 - 0.072 12.8 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor protein DUF2884 PF11101.3 EME30278.1 - 0.08 12.3 3.3 0.12 11.6 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) HR1 PF02185.11 EME30278.1 - 0.082 12.6 0.7 0.11 12.1 0.5 1.4 1 1 0 1 1 1 0 Hr1 repeat Transposase_22 PF02994.9 EME30278.1 - 0.084 11.3 1.9 0.12 10.8 1.3 1.3 1 1 0 1 1 1 0 L1 transposable element YvrJ PF12841.2 EME30278.1 - 0.084 12.1 1.3 0.4 10.0 0.1 2.2 2 0 0 2 2 2 0 YvrJ protein family DUF935 PF06074.7 EME30278.1 - 0.085 11.5 0.9 0.092 11.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Sec5 PF15469.1 EME30278.1 - 0.094 12.4 0.2 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Mitofilin PF09731.4 EME30278.1 - 0.096 11.3 0.7 0.12 10.9 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein OmpH PF03938.9 EME30278.1 - 0.098 12.5 1.2 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.6 EME30278.1 - 0.11 11.7 0.9 0.12 11.5 0.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF241 PF03087.9 EME30278.1 - 0.13 11.7 2.4 0.14 11.5 1.7 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Phasin PF05597.6 EME30278.1 - 0.15 11.8 1.2 0.24 11.1 0.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MtrB PF05440.7 EME30278.1 - 0.17 11.9 0.6 1 9.4 0.1 1.9 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Sipho_Gp157 PF05565.6 EME30278.1 - 0.26 10.8 2.0 0.31 10.5 1.4 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Med9 PF07544.8 EME30278.1 - 0.42 10.3 2.9 1 9.1 2.0 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HalX PF08663.5 EME30278.1 - 2.4 8.2 5.1 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 HalX domain HSBP1 PF06825.7 EME30279.1 - 7.6e-27 92.6 2.4 1.1e-26 92.1 1.7 1.3 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Laminin_I PF06008.9 EME30279.1 - 0.0011 18.3 1.1 0.0012 18.1 0.8 1.0 1 0 0 1 1 1 1 Laminin Domain I Prominin PF05478.6 EME30279.1 - 0.0036 14.9 0.2 0.0036 14.9 0.2 1.0 1 0 0 1 1 1 1 Prominin Erythro-docking PF09277.6 EME30279.1 - 0.0048 16.5 0.1 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 Erythronolide synthase, docking DUF2130 PF09903.4 EME30279.1 - 0.0067 15.2 1.2 0.0083 14.8 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) CheZ PF04344.8 EME30279.1 - 0.012 15.3 0.4 0.013 15.2 0.3 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ FtsK_SpoIIIE PF01580.13 EME30279.1 - 0.013 14.9 0.2 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2365 PF10157.4 EME30279.1 - 0.021 14.7 0.2 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) GvpK PF05121.7 EME30279.1 - 0.027 14.2 3.4 0.09 12.6 0.1 2.1 1 1 1 2 2 2 0 Gas vesicle protein K phiKZ_IP PF12699.2 EME30279.1 - 0.028 13.3 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins BLOC1_2 PF10046.4 EME30279.1 - 0.035 14.2 1.1 0.084 13.0 0.8 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 EME30279.1 - 0.042 13.6 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EME30279.1 - 0.054 13.2 1.7 0.51 10.1 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4631 PF15450.1 EME30279.1 - 0.054 11.7 1.3 0.061 11.6 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) RRN3 PF05327.6 EME30279.1 - 0.059 11.4 0.2 0.067 11.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Syntaxin PF00804.20 EME30279.1 - 0.068 13.3 3.4 1 9.5 0.8 2.1 1 1 1 2 2 2 0 Syntaxin LOH1CR12 PF10158.4 EME30279.1 - 0.072 12.8 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor protein DUF2884 PF11101.3 EME30279.1 - 0.08 12.3 3.3 0.12 11.6 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) HR1 PF02185.11 EME30279.1 - 0.082 12.6 0.7 0.11 12.1 0.5 1.4 1 1 0 1 1 1 0 Hr1 repeat Transposase_22 PF02994.9 EME30279.1 - 0.084 11.3 1.9 0.12 10.8 1.3 1.3 1 1 0 1 1 1 0 L1 transposable element YvrJ PF12841.2 EME30279.1 - 0.084 12.1 1.3 0.4 10.0 0.1 2.2 2 0 0 2 2 2 0 YvrJ protein family DUF935 PF06074.7 EME30279.1 - 0.085 11.5 0.9 0.092 11.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Sec5 PF15469.1 EME30279.1 - 0.094 12.4 0.2 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Mitofilin PF09731.4 EME30279.1 - 0.096 11.3 0.7 0.12 10.9 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein OmpH PF03938.9 EME30279.1 - 0.098 12.5 1.2 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GPO PF05929.6 EME30279.1 - 0.11 11.7 0.9 0.12 11.5 0.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF241 PF03087.9 EME30279.1 - 0.13 11.7 2.4 0.14 11.5 1.7 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Phasin PF05597.6 EME30279.1 - 0.15 11.8 1.2 0.24 11.1 0.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MtrB PF05440.7 EME30279.1 - 0.17 11.9 0.6 1 9.4 0.1 1.9 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Sipho_Gp157 PF05565.6 EME30279.1 - 0.26 10.8 2.0 0.31 10.5 1.4 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Med9 PF07544.8 EME30279.1 - 0.42 10.3 2.9 1 9.1 2.0 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HalX PF08663.5 EME30279.1 - 2.4 8.2 5.1 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 HalX domain DNA_ligase_A_M PF01068.16 EME30280.1 - 3.7e-54 183.1 0.3 9.2e-54 181.8 0.2 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME30280.1 - 3e-45 154.2 0.3 5.8e-45 153.2 0.2 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME30280.1 - 5.6e-23 81.1 0.0 2.4e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EME30280.1 - 0.0013 18.3 0.4 0.43 10.2 0.1 2.9 2 0 0 2 2 2 2 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 EME30280.1 - 0.0073 16.0 0.2 0.16 11.6 0.1 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DMRL_synthase PF00885.14 EME30281.1 - 1.7e-25 89.3 0.2 1.9e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase OTU PF02338.14 EME30282.1 - 2.4e-11 44.2 0.0 3.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME30282.1 - 0.00011 21.5 0.3 0.077 12.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain AAA_2 PF07724.9 EME30283.1 - 9.3e-63 211.1 0.0 1.5e-56 190.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EME30283.1 - 2.5e-28 97.7 0.5 1.9e-27 94.9 0.4 2.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EME30283.1 - 4e-27 95.0 0.0 1.4e-14 54.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME30283.1 - 3e-19 69.1 0.2 1.4e-11 44.2 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME30283.1 - 4.3e-12 46.3 4.8 0.0005 20.1 0.0 5.2 3 3 2 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EME30283.1 - 5.4e-12 45.5 0.1 1.4e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 EME30283.1 - 9.6e-09 35.0 0.1 1.5e-05 24.7 0.0 3.5 3 0 0 3 3 2 1 Clp amino terminal domain IstB_IS21 PF01695.12 EME30283.1 - 1.4e-08 34.4 0.0 0.0056 16.1 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 EME30283.1 - 1.5e-08 34.8 6.8 0.00097 19.2 0.0 5.0 5 1 0 5 5 5 2 AAA domain AAA_14 PF13173.1 EME30283.1 - 2.3e-08 33.9 3.6 0.018 14.9 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 EME30283.1 - 3.4e-08 33.8 0.0 0.0046 17.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME30283.1 - 9.7e-07 29.6 4.3 0.0093 16.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EME30283.1 - 2.5e-06 26.7 0.0 0.00087 18.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.16 EME30283.1 - 1e-05 24.7 0.5 0.24 10.5 0.1 3.7 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EME30283.1 - 4.4e-05 23.1 0.0 0.011 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EME30283.1 - 0.00011 21.9 0.0 0.17 11.5 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.6 EME30283.1 - 0.00037 20.1 0.2 0.12 11.9 0.0 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EME30283.1 - 0.00039 20.3 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 1 Torsin RNA_helicase PF00910.17 EME30283.1 - 0.00042 20.4 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EME30283.1 - 0.00057 20.1 1.1 0.15 12.3 0.0 3.7 3 0 0 3 3 3 1 ABC transporter MMR_HSR1 PF01926.18 EME30283.1 - 0.00092 19.1 0.0 0.93 9.4 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EME30283.1 - 0.0014 18.6 0.0 1 9.3 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME30283.1 - 0.0015 17.9 1.7 1.4 8.2 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 EME30283.1 - 0.0017 18.0 0.1 0.56 10.0 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain DNA_pol3_delta2 PF13177.1 EME30283.1 - 0.0063 16.1 0.0 0.2 11.2 0.0 3.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_33 PF13671.1 EME30283.1 - 0.0071 16.2 0.0 2 8.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME30283.1 - 0.011 14.9 0.0 2.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 EME30283.1 - 0.011 15.5 2.4 0.79 9.5 0.0 3.6 3 2 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EME30283.1 - 0.015 14.7 4.0 1.6 8.1 0.0 3.6 3 2 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 EME30283.1 - 0.017 14.8 11.0 0.61 9.7 0.4 4.7 4 2 1 5 5 5 0 Archaeal ATPase NTPase_1 PF03266.10 EME30283.1 - 0.021 14.5 0.0 14 5.3 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.1 EME30283.1 - 0.064 12.7 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.12 EME30283.1 - 0.1 12.4 12.4 2.3 7.9 0.0 4.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EME30283.1 - 0.19 12.0 0.0 0.19 12.0 0.0 4.3 2 1 1 3 3 2 0 AAA domain DUF2098 PF09871.4 EME30283.1 - 0.78 9.7 4.3 3.5 7.6 1.5 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Reticulon PF02453.12 EME30284.1 - 3.5e-32 111.3 8.1 4.7e-32 110.9 5.6 1.1 1 0 0 1 1 1 1 Reticulon AIF_C PF14721.1 EME30285.1 - 0.14 12.3 0.5 0.31 11.2 0.3 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MIF4G PF02854.14 EME30286.1 - 4.2e-27 94.9 1.3 4.2e-27 94.9 0.9 2.2 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EME30286.1 - 4.6e-18 64.9 0.5 1.1e-17 63.6 0.3 1.7 1 0 0 1 1 1 1 MA3 domain tRNA_int_endo PF01974.12 EME30287.1 - 5.5e-18 64.5 0.1 9.6e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SAP PF02037.22 EME30287.1 - 0.0042 16.5 0.1 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain Orn_Arg_deC_N PF02784.11 EME30288.1 - 3.3e-67 226.3 0.0 4.1e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME30288.1 - 4.4e-23 81.1 0.0 1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Erg28 PF03694.8 EME30289.1 - 5.2e-16 58.6 0.8 6.7e-16 58.2 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF202 PF02656.10 EME30289.1 - 5.9 7.1 9.6 42 4.4 6.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Erg28 PF03694.8 EME30290.1 - 5.2e-16 58.6 0.8 6.7e-16 58.2 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF202 PF02656.10 EME30290.1 - 0.53 10.5 4.2 1.3 9.3 2.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) PROCN PF08083.6 EME30291.1 - 5.9e-220 729.8 7.2 9.5e-220 729.1 5.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EME30291.1 - 8.3e-127 421.2 0.7 1.5e-126 420.3 0.5 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EME30291.1 - 2.1e-93 309.9 1.1 4.5e-93 308.9 0.8 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EME30291.1 - 8.9e-80 265.6 2.9 8.9e-80 265.6 2.0 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EME30291.1 - 1.1e-70 235.5 0.1 2.4e-70 234.4 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EME30291.1 - 8.3e-44 148.3 0.0 1.9e-43 147.1 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EME30291.1 - 2.5e-43 145.8 0.2 6.9e-43 144.4 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EME30291.1 - 0.0021 17.8 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Exo_endo_phos PF03372.18 EME30292.1 - 8.6e-15 55.3 0.0 1.4e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME30292.1 - 0.0035 16.9 0.5 0.0077 15.8 0.3 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TMEM51 PF15345.1 EME30292.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 Sugar_tr PF00083.19 EME30294.1 - 1.4e-25 89.7 35.6 1.1e-13 50.6 7.1 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME30294.1 - 5.9e-14 51.5 39.2 1.5e-07 30.4 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GUN4 PF05419.7 EME30294.1 - 0.13 12.0 1.3 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 GUN4-like Aconitase PF00330.15 EME30295.1 - 1.6e-158 528.0 0.3 2.3e-157 524.2 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME30295.1 - 4e-47 159.5 0.0 7.5e-47 158.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.15 EME30296.1 - 1.6e-158 528.0 0.3 2.3e-157 524.2 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME30296.1 - 4e-47 159.5 0.0 7.5e-47 158.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Myb_DNA-binding PF00249.26 EME30297.1 - 8.3e-13 48.1 0.0 2.2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME30297.1 - 0.045 13.8 0.6 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF641 PF04859.7 EME30297.1 - 0.13 11.9 4.1 0.051 13.3 0.8 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) HAUS-augmin3 PF14932.1 EME30297.1 - 0.16 11.0 10.8 0.31 10.1 7.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.3 EME30297.1 - 0.28 10.4 4.8 0.45 9.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4094 PF13334.1 EME30297.1 - 3.7 7.9 11.5 0.62 10.4 3.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Lum_binding PF00677.12 EME30298.1 - 6.1e-46 154.2 0.0 2e-23 82.0 0.0 2.0 2 0 0 2 2 2 2 Lumazine binding domain Corona_M PF01635.13 EME30298.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Methyltransf_11 PF08241.7 EME30299.1 - 4.2e-25 88.0 0.0 7.9e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME30299.1 - 3.7e-17 62.3 0.0 5.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME30299.1 - 3e-14 53.0 0.0 1.5e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30299.1 - 1.6e-13 50.9 0.0 3.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30299.1 - 4.6e-13 49.3 0.0 8.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME30299.1 - 1.4e-12 47.2 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EME30299.1 - 2.6e-12 46.3 0.0 4.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EME30299.1 - 3.1e-11 43.8 0.0 6.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30299.1 - 6e-08 32.7 0.0 1.8e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME30299.1 - 7.8e-06 25.3 0.0 1.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EME30299.1 - 0.00011 20.7 0.0 0.00016 20.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EME30299.1 - 0.0012 17.8 0.1 0.0047 16.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 EME30299.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EME30299.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EME30299.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 EME30299.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Hemerythrin PF01814.18 EME30300.1 - 2.1e-06 27.9 4.8 8.8e-06 25.9 0.6 1.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain UPF0051 PF01458.12 EME30302.1 - 3.7e-65 219.6 0.0 5.1e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Na_H_Exchanger PF00999.16 EME30303.1 - 1.3e-33 116.1 37.6 1.6e-33 115.8 26.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-Tim10_DDP PF02953.10 EME30304.1 - 3.1e-23 80.8 1.9 3.6e-23 80.6 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TIL PF01826.12 EME30304.1 - 0.093 12.8 0.5 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain BUD22 PF09073.5 EME30306.1 - 0.00023 20.3 3.0 0.00023 20.3 2.1 2.3 1 1 2 3 3 3 2 BUD22 ETF_alpha PF00766.14 EME30307.1 - 6.7e-39 131.4 1.3 1.1e-38 130.7 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EME30307.1 - 1.1e-28 100.0 0.2 2e-28 99.1 0.0 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain Cyclin_N PF00134.18 EME30308.1 - 7.4e-49 164.5 3.9 2.6e-47 159.5 0.5 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME30308.1 - 4.6e-27 94.2 1.4 4.6e-27 94.2 1.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF4638 PF15472.1 EME30308.1 - 0.0046 16.5 0.8 0.0066 16.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) CMD PF02627.15 EME30309.1 - 0.00024 20.8 0.0 0.0009 19.0 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BDV_P24 PF06595.6 EME30309.1 - 0.041 13.6 0.0 0.075 12.7 0.0 1.4 1 1 0 1 1 1 0 Borna disease virus P24 protein RRM_6 PF14259.1 EME30310.1 - 6.5e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30310.1 - 1.9e-08 34.0 0.0 3.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME30310.1 - 1.9e-06 27.4 0.0 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_BBRF1 PF04793.7 EME30310.1 - 0.054 12.2 0.8 0.16 10.6 0.8 1.5 2 0 0 2 2 2 0 BRRF1-like protein LTXXQ PF07813.7 EME30310.1 - 0.065 13.6 0.7 0.16 12.4 0.5 1.7 1 0 0 1 1 1 0 LTXXQ motif family protein Allexi_40kDa PF05549.6 EME30310.1 - 0.97 8.6 3.9 1.8 7.7 1.3 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2419 PF10343.4 EME30311.1 - 8.5e-81 271.3 0.8 1e-80 271.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Porin_3 PF01459.17 EME30312.1 - 2.2e-42 145.2 5.3 2.8e-42 144.9 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin JmjC PF02373.17 EME30312.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Transaldolase PF00923.14 EME30313.1 - 2.6e-100 335.2 0.1 3.1e-100 335.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase adh_short PF00106.20 EME30314.1 - 6e-23 81.5 0.0 1.1e-22 80.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME30314.1 - 2.1e-10 40.5 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME30314.1 - 2.2e-08 34.1 0.0 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME30314.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME30314.1 - 0.04 12.8 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ost4 PF10215.4 EME30315.1 - 0.057 12.9 0.2 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase Ost4 PF10215.4 EME30316.1 - 0.12 11.8 1.9 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 Oligosaccaryltransferase CBM_3 PF00942.13 EME30317.1 - 0.064 13.2 0.1 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Cellulose binding domain SAM_1 PF00536.25 EME30319.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1730 PF08331.5 EME30323.1 - 1.9e-18 65.8 0.0 6.5e-18 64.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.1 EME30323.1 - 4.5e-16 59.3 5.3 9.6e-16 58.2 3.7 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EME30323.1 - 9.7e-09 34.8 6.4 2.2e-08 33.7 4.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EME30323.1 - 8.4e-07 29.2 5.6 5.8e-06 26.5 4.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EME30323.1 - 5.3e-06 26.6 6.4 1.3e-05 25.3 4.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EME30323.1 - 0.00041 20.7 2.6 0.043 14.2 0.1 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EME30323.1 - 0.0021 17.5 10.7 0.075 12.6 1.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain HEAT_2 PF13646.1 EME30323.1 - 0.0029 17.8 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Fer4_6 PF12837.2 EME30323.1 - 0.0062 16.3 7.8 0.25 11.3 1.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EME30323.1 - 0.0077 16.2 9.7 0.09 12.8 7.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EME30323.1 - 0.01 15.7 8.4 0.096 12.5 5.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 EME30323.1 - 0.014 15.9 13.0 0.42 11.3 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.2 EME30323.1 - 0.025 14.9 9.0 1.1 9.7 2.6 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 EME30323.1 - 0.15 12.0 13.4 1.4 9.0 2.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_11 PF13247.1 EME30323.1 - 0.71 9.8 4.8 17 5.3 3.4 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 EME30323.1 - 1.3 9.3 10.5 15 5.9 7.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain RNase_PH PF01138.16 EME30324.1 - 3e-15 56.7 0.0 7.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME30324.1 - 4.6e-10 39.2 0.0 1.3e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Lysine_decarbox PF03641.9 EME30325.1 - 1.7e-25 89.3 0.1 8e-25 87.1 0.0 2.1 2 1 1 3 3 3 1 Possible lysine decarboxylase MazG PF03819.12 EME30325.1 - 1.6e-06 27.9 0.2 1.6e-06 27.9 0.2 2.2 3 0 0 3 3 3 1 MazG nucleotide pyrophosphohydrolase domain GMC_oxred_N PF00732.14 EME30326.1 - 1.4e-45 155.7 0.0 2.1e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EME30326.1 - 0.00016 21.6 0.2 0.00035 20.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME30326.1 - 0.00017 20.6 0.1 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME30326.1 - 0.00041 19.3 0.0 0.00057 18.9 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME30326.1 - 0.0038 16.1 0.0 0.0052 15.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME30326.1 - 0.0064 15.0 0.0 0.0086 14.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EME30326.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME30326.1 - 0.12 12.8 0.1 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.8 EME30327.1 - 1.1e-23 84.0 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EME30327.1 - 1.2e-18 67.3 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Nop PF01798.13 EME30328.1 - 1.4e-60 202.9 0.1 3.3e-60 201.7 0.1 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EME30328.1 - 1.4e-27 95.2 0.8 4.3e-27 93.6 0.1 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EME30328.1 - 1e-14 54.4 3.4 1e-14 54.4 2.3 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 EME30328.1 - 1.2 9.0 19.5 1.8 8.4 13.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family B3_4 PF03483.12 EME30329.1 - 3.7e-17 62.3 0.0 6.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EME30329.1 - 5.5e-17 61.3 0.1 1.3e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Pkinase PF00069.20 EME30330.1 - 8.2e-70 234.9 0.1 1.6e-69 233.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30330.1 - 6.7e-42 143.3 0.0 1e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30330.1 - 9.5e-06 24.7 0.1 2.7e-05 23.2 0.0 1.7 2 1 0 2 2 2 1 Kinase-like CBS PF00571.23 EME30332.1 - 2.9e-12 46.1 2.9 0.013 15.2 0.0 5.0 4 2 0 4 4 4 4 CBS domain Tubulin PF00091.20 EME30334.1 - 1.3e-75 253.9 0.0 1.9e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME30334.1 - 3.9e-47 159.4 0.0 6.9e-47 158.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME30334.1 - 6.1e-08 32.7 0.0 1.8e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Chorismate_synt PF01264.16 EME30334.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase CwfJ_C_1 PF04677.10 EME30335.1 - 4.4e-27 94.1 2.0 7.1e-27 93.4 1.4 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EME30335.1 - 1.8e-20 73.2 0.0 6.6e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF3401 PF11881.3 EME30335.1 - 0.42 9.9 7.6 0.81 9.0 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3401) Dfp1_Him1_M PF08630.5 EME30335.1 - 0.72 9.6 4.8 0.41 10.4 0.6 2.5 2 1 1 3 3 3 0 Dfp1/Him1, central region Nipped-B_C PF12830.2 EME30335.1 - 1.9 8.0 10.1 0.54 9.8 4.2 2.2 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus Histidinol_dh PF00815.15 EME30337.1 - 1.6e-129 432.2 0.1 1.8e-129 431.9 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase WD40 PF00400.27 EME30338.1 - 0.0031 17.3 13.2 0.025 14.4 0.8 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat NICE-3 PF07406.6 EME30339.1 - 0.0005 19.6 2.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 2 NICE-3 protein DUF1682 PF07946.9 EME30340.1 - 8.4e-47 159.5 3.1 1.1e-46 159.1 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Med19 PF10278.4 EME30340.1 - 0.0014 18.3 6.2 0.0024 17.5 4.3 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 NOP5NT PF08156.8 EME30340.1 - 0.36 11.0 3.7 0.43 10.7 0.0 2.7 2 1 1 3 3 3 0 NOP5NT (NUC127) domain Gastrin PF00918.12 EME30340.1 - 0.89 10.3 5.4 31 5.3 0.0 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family HA2 PF04408.18 EME30341.1 - 1.7e-30 105.0 0.2 3.3e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EME30341.1 - 1.2e-23 83.1 0.1 3.1e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EME30341.1 - 1.7e-14 53.4 0.0 4.6e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME30341.1 - 1.1e-07 31.4 0.1 4.8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME30341.1 - 2.7e-05 24.3 0.0 7.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EME30341.1 - 5.8e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 EME30341.1 - 0.00091 18.7 0.1 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EME30341.1 - 0.0035 16.9 0.0 0.0088 15.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EME30341.1 - 0.0064 15.4 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EME30341.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EME30341.1 - 0.024 13.8 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 EME30341.1 - 0.036 14.5 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EME30341.1 - 0.042 13.7 0.0 0.44 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EME30341.1 - 0.055 13.2 0.1 6 6.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EME30341.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EME30341.1 - 0.066 12.0 0.0 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 EME30341.1 - 0.069 13.4 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 EME30341.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EME30341.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EME30341.1 - 0.11 11.8 0.1 11 5.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EME30341.1 - 0.13 11.3 0.2 0.45 9.5 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin KaiC PF06745.8 EME30341.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC R3H PF01424.17 EME30342.1 - 4.5e-10 39.0 0.0 1.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 EME30342.1 - 0.00033 21.0 0.2 0.0013 19.2 0.1 2.1 1 0 0 1 1 1 1 SUZ domain HnRNPA1 PF11627.3 EME30342.1 - 0.014 15.5 1.2 0.032 14.3 0.8 1.6 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 SWIM PF04434.12 EME30343.1 - 7e-05 22.1 0.2 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger CTP_transf_3 PF02348.14 EME30343.1 - 0.0044 16.6 1.9 0.019 14.6 0.0 2.9 2 2 1 3 3 3 1 Cytidylyltransferase NUDIX PF00293.23 EME30344.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain DUF543 PF04418.7 EME30345.1 - 1.3e-16 60.2 0.2 1.7e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Lactamase_B_2 PF12706.2 EME30346.1 - 1.6e-26 93.1 0.0 3.4e-26 91.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME30346.1 - 4.9e-10 39.3 0.0 9.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 EME30346.1 - 0.25 10.2 0.6 0.45 9.3 0.1 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Peptidase_M20 PF01546.23 EME30348.1 - 3e-36 124.7 0.0 4.2e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME30348.1 - 0.00016 21.3 0.0 0.0009 18.9 0.0 2.2 2 1 0 2 2 2 1 Peptidase dimerisation domain YbaB_DNA_bd PF02575.11 EME30349.1 - 6.2e-13 48.4 1.0 9e-13 47.9 0.7 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF3326 PF11805.3 EME30349.1 - 0.0049 15.6 0.0 0.0074 15.0 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3326) DUF2664 PF10867.3 EME30349.1 - 0.14 12.8 0.6 0.27 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Hexapep PF00132.19 EME30350.1 - 1.9e-13 49.2 11.1 3.6e-06 26.2 0.0 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME30350.1 - 8.5e-09 34.8 6.2 0.0036 16.8 0.1 4.2 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Sdh5 PF03937.11 EME30350.1 - 0.062 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Adeno_E1B_19K PF01691.11 EME30350.1 - 0.063 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen UCH PF00443.24 EME30352.1 - 1.1e-50 172.2 0.3 1.1e-50 172.2 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME30352.1 - 4.6e-30 105.0 0.1 2.6e-29 102.5 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EME30352.1 - 5.1e-30 104.5 0.1 1.4e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EME30352.1 - 9.5e-14 51.3 0.0 6.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal B56 PF01603.15 EME30353.1 - 3.1e-66 223.6 5.0 3.9e-66 223.3 3.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) eIF3_N PF09440.5 EME30354.1 - 1.6e-38 131.9 4.6 1.7e-38 131.7 2.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EME30354.1 - 1.4e-15 57.5 0.1 4.1e-15 55.9 0.1 1.9 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.1 EME30354.1 - 0.063 13.6 0.4 0.47 10.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AICARFT_IMPCHas PF01808.13 EME30355.1 - 1.5e-114 382.3 0.1 2.1e-114 381.8 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EME30355.1 - 5.3e-19 67.9 0.0 1.1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain BING4CT PF08149.6 EME30355.1 - 0.069 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain DUF1767 PF08585.7 EME30357.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DUF1767 PF08585.7 EME30358.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Prefoldin_2 PF01920.15 EME30359.1 - 0.055 13.2 7.8 0.13 12.0 5.4 1.6 1 1 0 1 1 1 0 Prefoldin subunit PspA_IM30 PF04012.7 EME30359.1 - 0.24 10.7 4.7 0.29 10.4 3.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF1192 PF06698.6 EME30359.1 - 0.47 10.2 4.1 0.19 11.5 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF61 PF01886.11 EME30359.1 - 0.54 10.1 4.1 1.4 8.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF61 YgaB PF14182.1 EME30359.1 - 1.3 9.2 6.8 0.25 11.6 1.0 2.0 2 0 0 2 2 2 0 YgaB-like protein TBPIP PF07106.8 EME30359.1 - 1.7 8.1 9.5 0.16 11.5 2.1 1.9 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PseudoU_synth_2 PF00849.17 EME30361.1 - 1.3e-28 99.8 0.0 1.6e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase PHF5 PF03660.9 EME30362.1 - 4.4e-49 165.0 12.8 4.9e-49 164.8 8.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 EME30362.1 - 0.031 11.9 2.6 0.036 11.7 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Vip3A_N PF12495.3 EME30364.1 - 1.5 8.4 5.3 1.4 8.5 0.6 2.9 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Tropomyosin_1 PF12718.2 EME30364.1 - 5.2 6.8 54.7 0.11 12.3 8.3 4.0 3 1 1 4 4 4 0 Tropomyosin like PPR_2 PF13041.1 EME30365.1 - 1.3e-71 236.4 24.6 4e-10 39.5 0.0 14.3 8 4 6 14 14 14 12 PPR repeat family PPR_3 PF13812.1 EME30365.1 - 3.6e-49 160.9 12.5 0.00046 20.2 0.0 15.8 18 0 0 18 18 18 9 Pentatricopeptide repeat domain PPR PF01535.15 EME30365.1 - 6.6e-45 148.0 39.5 0.00024 20.8 0.0 17.6 18 1 0 18 18 18 11 PPR repeat PPR_1 PF12854.2 EME30365.1 - 1.7e-31 107.3 32.1 2.4e-06 26.9 0.1 15.2 17 0 0 17 17 17 8 PPR repeat TPR_19 PF14559.1 EME30365.1 - 2.3e-07 31.0 0.1 0.25 11.7 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME30365.1 - 2.4e-05 23.5 0.2 0.54 9.2 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat MRP-S27 PF10037.4 EME30365.1 - 8.2e-05 21.6 0.1 0.11 11.3 0.0 3.4 3 0 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_16 PF13432.1 EME30365.1 - 0.00059 20.4 0.3 0.58 10.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME30365.1 - 0.15 11.9 2.3 15 5.7 0.0 4.8 7 1 1 8 8 8 0 Tetratricopeptide repeat HI0933_like PF03486.9 EME30366.1 - 1.1e-106 356.7 0.0 1.3e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EME30366.1 - 3.4e-06 26.1 0.1 0.041 12.7 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EME30366.1 - 7.9e-06 25.0 0.0 8e-05 21.7 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME30366.1 - 0.002 18.2 0.0 0.016 15.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME30366.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME30366.1 - 0.0035 16.2 0.1 0.013 14.3 0.0 2.0 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EME30366.1 - 0.0039 17.1 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME30366.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EME30366.1 - 0.011 14.8 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME30366.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EME30366.1 - 0.043 14.2 0.3 1.7 9.1 0.0 3.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME30366.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EME30366.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SUI1 PF01253.17 EME30367.1 - 2e-14 53.1 0.0 4.9e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EME30367.1 - 0.066 12.8 1.4 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein LAG1-DNAbind PF09271.6 EME30368.1 - 0.016 15.7 0.1 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 LAG1, DNA binding Mago_nashi PF02792.9 EME30368.1 - 0.17 11.5 1.6 0.21 11.2 1.0 1.2 1 1 0 1 1 1 0 Mago nashi protein HEAT_2 PF13646.1 EME30369.1 - 0.11 12.8 0.5 36 4.7 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats Glyco_tranf_2_2 PF10111.4 EME30370.1 - 5.5e-09 35.4 0.3 5e-06 25.8 0.1 2.3 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME30370.1 - 9e-09 35.2 0.1 2.9e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 EME30370.1 - 2.7e-07 29.9 0.0 7.9e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 EME30370.1 - 0.02 14.7 0.0 0.63 9.7 0.0 2.7 2 1 1 3 3 3 0 Glycosyltransferase like family 2 DUF3885 PF13021.1 EME30370.1 - 0.055 13.1 0.3 0.44 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Fumble PF03630.9 EME30371.1 - 1.4e-109 366.0 0.0 2.8e-109 365.0 0.0 1.5 1 1 0 1 1 1 1 Fumble Fumble PF03630.9 EME30372.1 - 1.1e-98 330.2 0.0 2.7e-98 328.9 0.0 1.5 1 1 0 1 1 1 1 Fumble HABP4_PAI-RBP1 PF04774.10 EME30373.1 - 2.3e-10 40.9 6.1 2.3e-10 40.9 4.2 4.5 3 2 2 5 5 5 1 Hyaluronan / mRNA binding family BCDHK_Adom3 PF10436.4 EME30374.1 - 4.2e-38 130.4 1.6 6e-38 129.9 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EME30374.1 - 2.4e-18 65.8 0.0 5.6e-17 61.4 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME30374.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2854 PF11016.3 EME30375.1 - 6.8e-35 119.7 0.0 9.4e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) S1 PF00575.18 EME30376.1 - 9.9e-38 128.0 10.7 5.1e-19 68.1 1.2 2.6 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.1 EME30376.1 - 1.5e-05 24.7 0.8 0.23 11.3 0.0 3.3 3 0 0 3 3 3 2 S1 domain PsbN PF02468.10 EME30376.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) CCT PF06203.9 EME30377.1 - 6.8e-05 22.4 12.5 0.0001 21.8 8.6 1.3 1 0 0 1 1 1 1 CCT motif Sugar_tr PF00083.19 EME30378.1 - 1.9e-75 254.1 21.7 2.5e-75 253.7 15.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30378.1 - 2.7e-27 95.3 31.4 2.6e-21 75.7 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 EME30379.1 - 2.9e-07 29.6 0.0 5.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EME30379.1 - 7e-06 26.4 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EME30379.1 - 0.00012 21.6 0.0 0.00044 19.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain RWP-RK PF02042.10 EME30380.1 - 1.2e-14 53.8 0.5 2.4e-14 52.8 0.4 1.5 1 0 0 1 1 1 1 RWP-RK domain Prominin PF05478.6 EME30380.1 - 0.011 13.2 0.3 0.011 13.2 0.2 1.7 2 0 0 2 2 2 0 Prominin TMF_TATA_bd PF12325.3 EME30380.1 - 0.13 11.9 3.0 0.64 9.7 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EME30380.1 - 1.3 8.8 8.1 0.68 9.7 0.3 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 EME30380.1 - 1.3 8.5 5.3 0.3 10.6 0.6 2.2 3 0 0 3 3 3 0 Septum formation initiator GFO_IDH_MocA PF01408.17 EME30381.1 - 7.1e-16 58.8 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EME30381.1 - 0.0048 17.3 0.2 0.021 15.2 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 EME30381.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Vac_ImportDeg PF09783.4 EME30382.1 - 7.4e-46 155.8 0.1 8.8e-46 155.6 0.1 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein MutL_C PF08676.6 EME30383.1 - 2.9e-23 82.0 0.0 5.9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EME30383.1 - 1e-16 60.4 0.0 2.2e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EME30383.1 - 1.5e-12 47.3 0.0 4.4e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME30383.1 - 1.1e-09 37.9 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol_B PF00136.16 EME30384.1 - 3.7e-77 260.1 0.0 6.7e-77 259.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME30384.1 - 2.4e-18 66.0 0.2 4.2e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EME30384.1 - 2.2e-10 40.3 8.3 5.3e-10 39.1 5.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PQ-loop PF04193.9 EME30385.1 - 3.4e-23 80.9 14.8 4.3e-12 45.3 2.6 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 EME30385.1 - 0.0076 16.0 4.2 0.026 14.3 2.9 2.0 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange IBN_N PF03810.14 EME30386.1 - 0.0086 15.9 0.4 0.048 13.5 0.3 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain zf-RING_2 PF13639.1 EME30387.1 - 1.4e-12 47.2 7.6 2.4e-12 46.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME30387.1 - 1.2e-08 34.8 5.4 2.7e-08 33.7 3.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME30387.1 - 2.6e-08 33.4 5.4 4.6e-08 32.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30387.1 - 2.6e-07 30.2 3.1 4.1e-07 29.5 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME30387.1 - 7e-07 29.1 7.1 1.4e-06 28.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30387.1 - 2.6e-06 27.0 4.9 4.4e-06 26.3 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME30387.1 - 8.8e-06 25.4 3.0 1.5e-05 24.7 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME30387.1 - 0.0041 16.6 1.9 0.0076 15.8 1.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EME30387.1 - 0.032 13.9 4.2 0.1 12.3 2.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME30387.1 - 0.065 13.1 5.1 0.17 11.8 3.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EME30387.1 - 0.71 9.6 4.5 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EME30387.1 - 2 8.5 6.6 4.1 7.5 4.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME30387.1 - 2.4 8.2 6.1 34 4.4 4.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EME30387.1 - 7.5 6.6 8.3 4.3 7.4 3.9 2.0 2 0 0 2 2 2 0 RING-like domain Acetyltransf_7 PF13508.1 EME30388.1 - 1.5e-12 47.4 0.4 1.5e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME30388.1 - 9.9e-09 35.1 0.1 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyoxalase_2 PF12681.2 EME30388.1 - 7.8e-07 29.6 0.0 0.0001 22.8 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase-like domain Acetyltransf_10 PF13673.1 EME30388.1 - 5.6e-06 26.4 0.0 1.6e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 EME30388.1 - 1.9e-05 24.6 0.1 7.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_CG PF14542.1 EME30388.1 - 0.00046 20.0 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EME30388.1 - 0.0028 17.4 0.0 0.0064 16.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME30388.1 - 0.003 17.2 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Glyoxalase_4 PF13669.1 EME30388.1 - 0.0034 17.3 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1863 PF08937.6 EME30388.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Maf PF02545.9 EME30389.1 - 1.1e-51 174.6 0.0 1.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Aa_trans PF01490.13 EME30390.1 - 3.3e-50 170.7 37.2 4e-50 170.4 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME30390.1 - 1e-06 27.8 16.6 1e-06 27.8 11.5 2.5 1 1 0 3 3 3 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EME30390.1 - 9.2e-05 21.2 25.9 0.00017 20.3 18.0 1.3 1 0 0 1 1 1 1 Spore germination protein Complex1_LYR_2 PF13233.1 EME30391.1 - 0.0071 16.8 0.2 0.0087 16.5 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like NYD-SP28_assoc PF14775.1 EME30391.1 - 0.0094 15.6 0.4 0.02 14.5 0.1 1.7 2 0 0 2 2 2 1 Sperm tail C-terminal domain Alpha_adaptin_C PF02296.11 EME30391.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain tRNA_synt_2f PF02092.12 EME30391.1 - 0.07 11.6 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit PA26 PF04636.8 EME30393.1 - 1.3e-104 350.4 0.0 1.8e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Glyoxalase_2 PF12681.2 EME30394.1 - 6e-07 30.0 0.0 7.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME30394.1 - 0.00013 21.9 0.0 0.00098 19.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_31 PF13847.1 EME30395.1 - 5.5e-11 42.2 0.1 9.6e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME30395.1 - 1.9e-10 40.3 0.0 3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EME30395.1 - 7.2e-09 36.2 0.0 1.6e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME30395.1 - 4.8e-08 32.5 0.1 8.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME30395.1 - 5.4e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EME30395.1 - 3e-07 29.4 0.1 4.4e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 EME30395.1 - 8.5e-07 29.3 0.0 2.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EME30395.1 - 9.1e-07 28.1 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EME30395.1 - 1.2e-05 25.1 0.0 2.2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME30395.1 - 1.4e-05 24.2 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EME30395.1 - 4.3e-05 23.1 0.1 7.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EME30395.1 - 0.00011 22.6 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30395.1 - 0.0004 20.7 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME30395.1 - 0.00067 18.7 0.1 0.0019 17.3 0.1 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EME30395.1 - 0.0072 16.3 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EME30395.1 - 0.0096 15.3 0.2 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase DOT1 PF08123.8 EME30395.1 - 0.017 14.4 0.1 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.9 EME30395.1 - 0.02 14.0 0.4 0.046 12.8 0.2 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.11 EME30395.1 - 0.026 14.1 0.2 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 EME30395.1 - 0.034 13.7 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EME30395.1 - 0.05 13.2 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Herpes_UL49_2 PF04823.7 EME30395.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Linker_histone PF00538.14 EME30396.1 - 1.8e-12 47.1 1.1 1.8e-12 47.1 0.8 2.3 2 1 1 3 3 3 1 linker histone H1 and H5 family PAD_porph PF04371.10 EME30397.1 - 8.6e-126 419.4 0.1 9.7e-126 419.2 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.12 EME30397.1 - 0.14 11.2 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Amidinotransferase TRAUB PF08164.7 EME30398.1 - 5.2e-14 52.0 2.5 5.2e-14 52.0 1.7 3.3 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EME30398.1 - 4.6e-10 39.7 1.2 4.6e-10 39.7 0.8 3.7 3 2 1 4 4 4 2 Apoptosis antagonizing transcription factor Cse1 PF08506.5 EME30400.1 - 3.5e-116 387.7 0.6 7.5e-116 386.7 0.1 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 EME30400.1 - 2.2e-106 355.7 3.4 2e-105 352.5 3.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EME30400.1 - 1.1e-12 47.6 0.0 6.3e-12 45.2 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pyrid_oxidase_2 PF13883.1 EME30401.1 - 1.8e-21 76.6 0.0 3.8e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.4 EME30401.1 - 4.4e-10 39.6 0.0 9.3e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyridox_oxidase PF01243.15 EME30401.1 - 1.6e-05 24.8 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HAD_2 PF13419.1 EME30402.1 - 2.2e-21 76.8 0.4 3e-21 76.4 0.3 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME30402.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EME30402.1 - 0.038 13.6 0.2 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Acid Phosphatase Hydrolase PF00702.21 EME30402.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase WW PF00397.21 EME30403.1 - 7.8e-10 38.4 5.0 7.8e-10 38.4 3.5 2.0 2 0 0 2 2 2 1 WW domain DUF1487 PF07368.6 EME30403.1 - 0.093 11.9 2.9 2.9 7.0 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1487) Sec8_exocyst PF04048.9 EME30403.1 - 0.1 12.2 5.1 0.085 12.4 1.2 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BAR PF03114.13 EME30404.1 - 1.2e-05 24.9 6.5 1.2e-05 24.9 4.5 1.9 2 0 0 2 2 2 1 BAR domain DUF3538 PF12057.3 EME30404.1 - 0.00011 21.7 0.2 0.00065 19.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3538) M_domain PF12938.2 EME30404.1 - 0.074 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 M domain of GW182 ELK PF03789.8 EME30404.1 - 0.11 12.3 1.0 0.32 10.8 0.7 1.9 1 0 0 1 1 1 0 ELK domain DUF342 PF03961.8 EME30404.1 - 0.11 10.8 1.7 0.17 10.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Wbp11 PF09429.5 EME30404.1 - 0.55 10.2 9.8 1.5 8.8 6.8 1.8 1 0 0 1 1 1 0 WW domain binding protein 11 FTA4 PF13093.1 EME30404.1 - 1.9 7.8 11.0 2.9 7.2 3.3 2.4 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Mnd1 PF03962.10 EME30404.1 - 6.6 6.3 11.5 0.85 9.2 4.6 1.8 1 1 1 2 2 2 0 Mnd1 family Aldo_ket_red PF00248.16 EME30405.1 - 3.1e-60 203.4 0.0 3.7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_63 PF03200.11 EME30406.1 - 8e-171 569.7 4.6 1.5e-169 565.5 3.2 2.0 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase DUF328 PF03883.9 EME30407.1 - 0.0025 17.1 1.0 0.0029 16.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF328) RICH PF05062.7 EME30407.1 - 0.02 15.0 2.5 0.027 14.6 1.7 1.2 1 0 0 1 1 1 0 RICH domain PAP_PilO PF06864.7 EME30407.1 - 0.074 11.3 0.0 0.1 10.9 0.0 1.2 1 1 0 1 1 1 0 Pilin accessory protein (PilO) Vac_ImportDeg PF09783.4 EME30407.1 - 0.23 10.9 1.9 0.29 10.6 1.3 1.1 1 0 0 1 1 1 0 Vacuolar import and degradation protein COX14 PF14880.1 EME30407.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF328 PF03883.9 EME30408.1 - 0.0025 17.1 1.0 0.0029 16.9 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF328) RICH PF05062.7 EME30408.1 - 0.02 15.0 2.5 0.027 14.6 1.7 1.2 1 0 0 1 1 1 0 RICH domain PAP_PilO PF06864.7 EME30408.1 - 0.074 11.3 0.0 0.1 10.9 0.0 1.2 1 1 0 1 1 1 0 Pilin accessory protein (PilO) Vac_ImportDeg PF09783.4 EME30408.1 - 0.23 10.9 1.9 0.29 10.6 1.3 1.1 1 0 0 1 1 1 0 Vacuolar import and degradation protein COX14 PF14880.1 EME30408.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF2439 PF10382.4 EME30409.1 - 2.6e-14 53.1 0.1 4.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Redoxin PF08534.5 EME30410.1 - 1.5e-32 112.1 0.0 1.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME30410.1 - 2.7e-15 56.1 0.0 7.5e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Hydrolase PF00702.21 EME30410.1 - 0.041 14.2 0.0 0.046 14.1 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.16 EME30412.1 - 2.2e-63 214.0 7.2 2.8e-63 213.6 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EME30412.1 - 0.0049 15.9 5.3 0.009 15.0 3.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter ArgK PF03308.11 EME30413.1 - 2.2e-78 262.7 0.3 3.9e-78 261.9 0.1 1.4 2 0 0 2 2 2 1 ArgK protein cobW PF02492.14 EME30413.1 - 5.8e-07 29.1 1.7 2.4e-06 27.1 0.4 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EME30413.1 - 5.5e-05 22.6 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 EME30413.1 - 0.0012 18.4 0.0 0.0079 15.7 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EME30413.1 - 0.0014 18.5 0.1 0.0034 17.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EME30413.1 - 0.011 16.6 0.1 0.024 15.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME30413.1 - 0.026 15.0 0.1 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 EME30413.1 - 0.04 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EME30413.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME30413.1 - 0.043 13.5 0.1 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase SRP54 PF00448.17 EME30413.1 - 0.05 13.0 0.0 0.19 11.1 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EME30413.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME30413.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EME30413.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 EME30413.1 - 0.096 12.2 0.0 0.3 10.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EME30413.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EME30413.1 - 0.11 12.1 0.2 0.77 9.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EME30413.1 - 0.13 12.1 0.1 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME30413.1 - 0.36 10.6 1.8 1.8 8.3 0.0 2.7 2 1 1 3 3 3 0 Part of AAA domain ArgK PF03308.11 EME30414.1 - 3.7e-82 275.1 1.0 5.6e-78 261.3 0.1 2.0 2 0 0 2 2 2 2 ArgK protein cobW PF02492.14 EME30414.1 - 3.7e-07 29.7 0.5 3.2e-06 26.7 0.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EME30414.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 EME30414.1 - 0.0015 18.0 0.0 0.0093 15.5 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EME30414.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EME30414.1 - 0.013 16.3 0.1 0.029 15.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME30414.1 - 0.031 14.7 0.1 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein GvpG PF05120.7 EME30414.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Gas vesicle protein G NTPase_1 PF03266.10 EME30414.1 - 0.046 13.4 0.1 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EME30414.1 - 0.047 13.9 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EME30414.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EME30414.1 - 0.06 12.7 0.0 0.24 10.7 0.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 EME30414.1 - 0.064 12.2 0.0 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.1 EME30414.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME30414.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EME30414.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EME30414.1 - 0.15 11.7 0.2 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_3 PF07859.8 EME30415.1 - 3.6e-47 160.6 0.0 5.4e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSL_N PF06350.7 EME30415.1 - 1.4e-19 70.3 0.1 3.4e-19 69.0 0.1 1.5 1 1 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus DUF2424 PF10340.4 EME30415.1 - 1.2e-14 53.7 0.0 1.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EME30415.1 - 0.00034 19.9 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EME30415.1 - 0.0023 17.8 0.1 0.004 17.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME30415.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EME30415.1 - 0.024 13.3 0.0 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Thioesterase PF00975.15 EME30415.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Transket_pyr PF02779.19 EME30416.1 - 4.4e-65 218.4 0.0 7.7e-65 217.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EME30416.1 - 7.1e-57 192.4 0.0 1.1e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component KH_1 PF00013.24 EME30417.1 - 2e-05 24.1 0.1 3.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 KH domain Dynamin_M PF01031.15 EME30418.1 - 2.6e-102 341.5 0.1 5.4e-102 340.5 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EME30418.1 - 1.4e-55 187.7 1.2 1.8e-55 187.2 0.1 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EME30418.1 - 4.3e-30 103.4 4.2 1e-29 102.2 2.9 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 EME30418.1 - 0.0016 18.9 0.2 0.0055 17.1 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME30418.1 - 0.0025 17.7 0.1 0.021 14.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAT1 PF09770.4 EME30418.1 - 0.85 7.7 20.0 1.4 7.1 13.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AOX PF01786.12 EME30419.1 - 1.3e-79 266.4 0.1 2e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Alternative oxidase DUF1593 PF07632.6 EME30419.1 - 0.054 12.8 0.2 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) GCV_H PF01597.14 EME30420.1 - 5.3e-44 148.8 1.0 6.2e-44 148.5 0.7 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Phasin PF05597.6 EME30420.1 - 0.033 13.9 0.1 0.049 13.4 0.1 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GSH_synth_ATP PF03917.12 EME30421.1 - 7.8e-98 327.4 0.0 8.7e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EME30421.1 - 2.1e-33 114.5 0.0 3.6e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase TraB PF01963.12 EME30422.1 - 4e-13 49.4 0.1 5e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 TraB family Ribosomal_S7 PF00177.16 EME30423.1 - 4.6e-13 48.9 0.0 5.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-RVT PF13966.1 EME30423.1 - 0.001 19.3 0.3 0.0032 17.7 0.2 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase PyocinActivator PF11112.3 EME30423.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyocin activator protein PrtN Ribosomal_S7 PF00177.16 EME30424.1 - 4.6e-13 48.9 0.0 5.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-RVT PF13966.1 EME30424.1 - 0.001 19.3 0.3 0.0032 17.7 0.2 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase PyocinActivator PF11112.3 EME30424.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyocin activator protein PrtN Pkinase PF00069.20 EME30425.1 - 1.3e-37 129.3 0.0 2.2e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Radical_SAM PF04055.16 EME30425.1 - 4.2e-29 101.8 0.2 7.7e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EME30425.1 - 2.6e-27 94.5 0.0 6e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Pkinase_Tyr PF07714.12 EME30425.1 - 3.4e-17 62.3 0.0 1.8e-16 60.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase TRAM PF01938.15 EME30425.1 - 1e-12 47.6 0.2 3.4e-12 45.9 0.2 1.9 2 0 0 2 2 2 1 TRAM domain Rotamase_3 PF13616.1 EME30425.1 - 1.2e-08 35.1 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EME30425.1 - 8.2e-07 29.6 0.0 2.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 PPIC-type PPIASE domain AAA PF00004.24 EME30426.1 - 3.3e-45 153.5 0.0 1.8e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME30426.1 - 7.1e-09 35.5 0.1 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME30426.1 - 1.3e-07 31.7 0.1 3.3e-07 30.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EME30426.1 - 7.8e-07 29.3 1.1 0.00016 21.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME30426.1 - 2.4e-06 27.6 0.1 3e-05 24.0 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EME30426.1 - 2.8e-05 23.1 0.2 7.6e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EME30426.1 - 0.00018 21.1 0.1 0.00042 20.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EME30426.1 - 0.0002 21.3 0.1 0.00053 19.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EME30426.1 - 0.00023 21.9 0.1 0.0017 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EME30426.1 - 0.00024 20.2 0.0 0.00049 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EME30426.1 - 0.00026 20.4 1.7 0.007 15.7 0.1 2.5 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EME30426.1 - 0.00029 20.2 0.3 0.00082 18.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EME30426.1 - 0.00039 20.3 0.1 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME30426.1 - 0.00044 20.3 0.0 0.0054 16.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.1 EME30426.1 - 0.00093 19.5 0.3 1.6 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EME30426.1 - 0.0014 17.7 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME30426.1 - 0.0015 18.8 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EME30426.1 - 0.0027 17.3 0.5 0.032 13.8 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EME30426.1 - 0.0027 17.5 0.0 0.0076 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EME30426.1 - 0.0029 17.2 0.3 0.014 15.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EME30426.1 - 0.003 16.3 0.0 0.0053 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EME30426.1 - 0.0047 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EME30426.1 - 0.0055 16.3 0.1 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EME30426.1 - 0.0075 15.9 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 NTPase Arch_ATPase PF01637.13 EME30426.1 - 0.0092 15.7 0.3 0.66 9.6 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 EME30426.1 - 0.0093 15.5 0.0 0.029 13.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EME30426.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EME30426.1 - 0.017 14.6 0.1 0.047 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EME30426.1 - 0.02 14.3 0.2 0.16 11.4 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 EME30426.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF3363 PF11843.3 EME30426.1 - 0.043 12.4 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) KaiC PF06745.8 EME30426.1 - 0.048 12.7 1.1 0.33 10.0 0.0 2.5 3 0 0 3 3 3 0 KaiC GrpE PF01025.14 EME30426.1 - 0.048 13.2 0.5 0.57 9.7 0.1 2.2 2 0 0 2 2 2 0 GrpE NB-ARC PF00931.17 EME30426.1 - 0.061 12.1 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EME30426.1 - 0.069 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EME30426.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_P18 PF04521.8 EME30426.1 - 0.2 11.1 0.6 0.39 10.1 0.4 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Guanylate_kin PF00625.16 EME30426.1 - 0.25 10.7 4.2 2 7.8 0.0 3.8 4 1 1 5 5 5 0 Guanylate kinase Sulfate_transp PF00916.15 EME30427.1 - 2.5e-72 243.2 15.4 4.8e-72 242.2 10.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EME30427.1 - 1.4e-27 95.2 3.2 1.4e-27 95.2 2.2 4.0 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EME30427.1 - 1.6e-14 53.3 0.2 4e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 STAS domain Ribosomal_L6 PF00347.18 EME30428.1 - 3.2e-09 37.1 0.2 7.3e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L6 CTP_transf_2 PF01467.21 EME30429.1 - 2.1e-21 76.6 0.0 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase CN_hydrolase PF00795.17 EME30430.1 - 1.6e-25 89.5 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EME30430.1 - 2.1e-23 82.5 0.0 6.9e-23 80.7 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EME30431.1 - 1.5e-25 89.6 0.0 2.6e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EME30431.1 - 1.8e-23 82.7 0.0 5.4e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 NAD synthase NT-C2 PF10358.4 EME30432.1 - 1.8e-21 76.1 0.0 3.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 EME30432.1 - 0.1 12.4 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 C2 domain NT-C2 PF10358.4 EME30433.1 - 1.6e-21 76.3 0.0 2.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.25 EME30433.1 - 0.093 12.5 0.2 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 C2 domain DUF4187 PF13821.1 EME30435.1 - 0.48 10.0 2.6 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) PHO4 PF01384.15 EME30436.1 - 5.2e-103 344.1 25.6 6.5e-103 343.8 17.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.5 EME30436.1 - 0.0038 16.7 0.4 1 8.9 0.0 2.6 2 0 0 2 2 2 2 IclR helix-turn-helix domain TctB PF07331.6 EME30436.1 - 0.48 10.0 39.5 0.051 13.2 2.8 3.9 1 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family ADH_zinc_N PF00107.21 EME30437.1 - 1.1e-05 25.0 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME30437.1 - 0.00042 20.0 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EME30438.1 - 0.00015 22.3 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30438.1 - 0.0078 16.2 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DnaJ PF00226.26 EME30439.1 - 3.8e-28 96.9 1.8 5.4e-28 96.5 1.3 1.2 1 0 0 1 1 1 1 DnaJ domain PhrC_PhrF PF11131.3 EME30439.1 - 0.051 13.1 0.5 0.088 12.3 0.4 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling Lactamase_B_2 PF12706.2 EME30441.1 - 9.4e-35 119.9 0.0 5.4e-30 104.3 0.2 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EME30441.1 - 1.3e-13 50.1 0.0 3.8e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EME30441.1 - 4.8e-11 42.6 0.1 1.2e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Pkinase PF00069.20 EME30442.1 - 2.2e-24 86.0 0.0 4.5e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30442.1 - 3.9e-07 29.4 0.0 9.1e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME30442.1 - 0.031 13.9 0.0 2.3 7.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sas10_Utp3 PF04000.10 EME30443.1 - 3.9e-20 71.8 0.2 3.9e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.5 EME30443.1 - 2.9e-14 53.0 8.2 2.9e-14 53.0 5.7 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Porin_3 PF01459.17 EME30444.1 - 1.2e-60 205.1 0.0 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Asparaginase_2 PF01112.13 EME30444.1 - 0.17 10.5 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Asparaginase Porin_3 PF01459.17 EME30445.1 - 1.2e-60 205.1 0.0 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Asparaginase_2 PF01112.13 EME30445.1 - 0.17 10.5 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Asparaginase Sugar_tr PF00083.19 EME30446.1 - 1.1e-91 307.7 39.7 1.2e-91 307.5 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30446.1 - 6.3e-21 74.4 69.6 2.7e-20 72.4 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME30446.1 - 2.3e-06 26.2 34.1 0.00054 18.4 4.9 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein Med4 PF10018.4 EME30447.1 - 1.1e-09 37.9 1.1 1.3e-09 37.7 0.7 1.0 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Fungal_trans PF04082.13 EME30447.1 - 0.064 12.1 0.1 0.073 11.9 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_S9 PF00326.16 EME30448.1 - 3.3e-35 121.2 0.0 7.4e-35 120.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME30448.1 - 5.4e-11 42.4 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME30448.1 - 6.3e-10 39.3 0.1 1.4e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME30448.1 - 3.5e-05 23.2 0.0 5.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EME30448.1 - 0.00031 20.2 0.0 0.041 13.3 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EME30448.1 - 0.0011 18.7 0.0 0.0068 16.1 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EME30448.1 - 0.0012 18.4 0.1 0.014 14.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold CtaG_Cox11 PF04442.9 EME30450.1 - 4.7e-59 198.5 0.4 7.2e-59 197.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 G-patch_2 PF12656.2 EME30450.1 - 0.043 13.6 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF674 PF05056.7 EME30452.1 - 0.046 12.3 0.1 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Alpha-amylase PF00128.19 EME30457.1 - 9.1e-61 205.9 0.0 1.4e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cpn60_TCP1 PF00118.19 EME30458.1 - 8.1e-147 489.7 6.4 9.2e-147 489.5 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAD_binding_10 PF13460.1 EME30459.1 - 3.9e-18 66.0 0.0 5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME30459.1 - 3.3e-17 62.7 0.0 5.7e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME30459.1 - 4.9e-17 61.5 0.1 8.2e-14 50.9 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME30459.1 - 2.4e-11 43.0 0.0 1.6e-07 30.4 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 EME30459.1 - 3.7e-06 26.0 0.1 0.12 11.2 0.0 3.1 1 1 2 3 3 3 2 Male sterility protein NmrA PF05368.8 EME30459.1 - 3.9e-06 26.2 0.0 6.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EME30459.1 - 0.00011 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EME30459.1 - 0.00032 19.8 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 EME30459.1 - 0.004 17.7 0.0 0.008 16.7 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 EME30459.1 - 0.014 15.0 0.0 0.051 13.2 0.0 1.8 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EME30459.1 - 0.047 12.5 0.0 0.18 10.6 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EME30459.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EME30459.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase FA_hydroxylase PF04116.8 EME30460.1 - 3.8e-12 46.5 12.3 3.8e-12 46.5 8.5 2.7 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Aldedh PF00171.17 EME30461.1 - 1.9e-15 56.1 2.6 4.9e-11 41.6 0.3 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family HSP90 PF00183.13 EME30462.1 - 5.6e-151 503.5 15.0 7.9e-150 499.7 10.4 2.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EME30462.1 - 2.1e-14 53.3 0.1 5.3e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME30462.1 - 1.3e-10 40.9 0.1 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3411 PF11891.3 EME30463.1 - 5.6e-44 149.9 0.0 8.2e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3411) Voltage_CLC PF00654.15 EME30463.1 - 0.0077 15.2 0.4 0.013 14.5 0.3 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel YchF-GTPase_C PF06071.8 EME30464.1 - 5.6e-40 135.0 0.1 9.3e-40 134.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EME30464.1 - 8.1e-20 70.9 0.0 2.7e-19 69.2 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME30464.1 - 1.7e-06 27.4 0.0 5.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EME30464.1 - 0.068 13.9 0.0 0.17 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Acyltransferase PF01553.16 EME30465.1 - 7.6e-17 60.9 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1700 PF08006.6 EME30465.1 - 1.3 8.2 6.7 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) CcmD PF04995.9 EME30465.1 - 3.2 7.5 5.4 7.5 6.3 1.6 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) zf-C2H2 PF00096.21 EME30466.1 - 2e-22 78.0 72.4 0.00043 20.4 2.1 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME30466.1 - 7.8e-21 72.8 74.1 0.0031 17.7 1.3 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME30466.1 - 1.4e-16 59.8 58.9 0.00034 20.7 1.0 9.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EME30466.1 - 0.0041 17.2 6.2 0.0078 16.3 1.3 7.8 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EME30466.1 - 0.0044 16.8 32.6 0.0098 15.7 0.4 6.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EME30466.1 - 0.011 15.4 0.8 0.011 15.4 0.6 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EME30467.1 - 2e-22 78.0 72.4 0.00043 20.4 2.1 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME30467.1 - 7.8e-21 72.8 74.1 0.0031 17.7 1.3 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME30467.1 - 1.4e-16 59.8 58.9 0.00034 20.7 1.0 9.4 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EME30467.1 - 0.0041 17.2 6.2 0.0078 16.3 1.3 7.8 8 0 0 8 8 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EME30467.1 - 0.0044 16.8 32.6 0.0098 15.7 0.4 6.7 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EME30467.1 - 0.011 15.4 0.8 0.011 15.4 0.6 7.0 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Pox_A6 PF04924.7 EME30468.1 - 0.019 13.7 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein EamA PF00892.15 EME30470.1 - 5.6e-08 32.8 30.3 0.00015 21.8 8.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EME30470.1 - 8.8e-06 25.4 16.2 8.8e-06 25.4 11.2 3.0 2 1 1 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 EME30470.1 - 0.009 16.2 25.4 0.07 13.3 2.9 3.1 2 2 1 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EME30470.1 - 0.018 14.0 22.5 0.1 11.5 15.6 1.9 1 1 0 1 1 1 0 UAA transporter family Glyco_hydro_42 PF02449.10 EME30470.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Nol1_Nop2_Fmu PF01189.12 EME30471.1 - 3.4e-81 272.7 0.0 4.8e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EME30471.1 - 2.2e-05 24.5 0.1 9.6e-05 22.4 0.0 2.1 2 1 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.11 EME30471.1 - 2.7e-05 23.8 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EME30471.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EME30471.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF885 PF05960.6 EME30472.1 - 2.5e-133 446.1 0.0 3.1e-133 445.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF1041 PF06292.12 EME30472.1 - 0.0043 17.1 0.1 0.017 15.2 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) HrpB7 PF09486.5 EME30472.1 - 0.085 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF885 PF05960.6 EME30473.1 - 1.5e-133 446.8 0.0 1.7e-133 446.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF1041 PF06292.12 EME30473.1 - 0.0042 17.2 0.1 0.016 15.3 0.1 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) DUF4455 PF14643.1 EME30473.1 - 0.069 11.7 0.7 0.3 9.6 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4455) HrpB7 PF09486.5 EME30473.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) KOW PF00467.24 EME30474.1 - 0.015 15.0 0.0 0.053 13.2 0.0 2.0 1 0 0 1 1 1 0 KOW motif FeoA PF04023.9 EME30474.1 - 0.06 13.3 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 FeoA domain Enolase_C PF00113.17 EME30475.1 - 6.9e-148 491.4 0.0 9.1e-148 491.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EME30475.1 - 1.6e-58 196.3 0.6 2.8e-58 195.5 0.5 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EME30475.1 - 0.00013 21.9 0.0 0.00036 20.4 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EME30475.1 - 0.014 14.3 0.0 0.032 13.1 0.0 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EME30475.1 - 0.07 13.6 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DSPn PF14671.1 EME30476.1 - 2e-34 118.5 0.5 5.6e-34 117.1 0.3 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EME30476.1 - 1.8e-12 46.9 0.3 6.6e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME30476.1 - 7.7e-06 25.4 0.0 1.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EME30476.1 - 8e-05 22.7 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EME30476.1 - 0.00031 21.0 0.0 0.00074 19.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EME30476.1 - 0.074 12.5 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GreA_GreB PF01272.14 EME30476.1 - 0.092 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term RRM_1 PF00076.17 EME30477.1 - 2.7e-27 94.1 0.6 1.1e-12 47.3 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30477.1 - 1.9e-16 59.6 0.2 1.1e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30477.1 - 6.7e-14 51.6 0.1 3e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 EME30477.1 - 5.8e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.1 EME30477.1 - 0.014 15.1 0.1 0.64 9.8 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EME30477.1 - 0.055 13.0 0.3 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 Calcipressin SHMT PF00464.14 EME30478.1 - 2.9e-184 612.0 0.0 3.3e-184 611.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EME30478.1 - 9e-06 24.8 0.0 2.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME30478.1 - 0.00034 19.8 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Sybindin PF04099.7 EME30479.1 - 1.1e-29 102.9 0.0 1.3e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EME30479.1 - 0.00016 21.5 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sugar_tr PF00083.19 EME30480.1 - 1.8e-93 313.6 31.3 2.1e-93 313.3 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30480.1 - 2.8e-17 62.4 45.8 7.8e-13 47.8 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME30480.1 - 0.0013 17.1 32.8 0.0028 16.1 5.8 3.0 2 1 0 3 3 3 2 MFS/sugar transport protein Pkinase_Tyr PF07714.12 EME30481.1 - 3.2e-62 209.9 0.0 4.3e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME30481.1 - 2.2e-55 187.6 0.0 3.9e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EME30481.1 - 0.00092 19.0 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME30481.1 - 0.01 14.8 0.1 0.023 13.6 0.0 1.5 2 0 0 2 2 2 0 Kinase-like LIN37 PF15306.1 EME30482.1 - 2.2e-09 37.4 0.8 4.7e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 LIN37 zf-C3HC4_3 PF13920.1 EME30483.1 - 3.5e-08 32.9 4.3 7.2e-08 31.9 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME30483.1 - 0.00063 19.7 3.7 0.0015 18.4 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_S13 PF00416.17 EME30483.1 - 0.011 16.1 1.6 3.6 8.0 0.3 2.7 3 0 0 3 3 3 0 Ribosomal protein S13/S18 DUF4359 PF14271.1 EME30483.1 - 0.018 15.4 0.4 0.04 14.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) WD40 PF00400.27 EME30484.1 - 1.7e-35 119.6 18.0 9.6e-09 34.7 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat RRM_3 PF08777.6 EME30485.1 - 4.7e-26 90.6 2.5 8e-24 83.5 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif La PF05383.12 EME30485.1 - 4.1e-23 80.9 0.3 1e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 EME30485.1 - 2.4e-21 75.1 0.2 1.2e-09 37.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30485.1 - 2.2e-20 72.4 0.0 7.8e-12 45.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30485.1 - 1.7e-11 43.7 0.1 4.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME30485.1 - 5.3e-08 32.5 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SurE PF01975.12 EME30486.1 - 1.3e-44 151.8 0.0 4e-44 150.2 0.0 1.7 1 1 0 1 1 1 1 Survival protein SurE SMC_N PF02463.14 EME30487.1 - 9.2e-26 90.4 0.0 1.7e-25 89.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME30487.1 - 2.9e-05 24.4 42.3 2.9e-05 24.4 29.3 6.4 3 2 2 5 5 4 1 AAA domain AAA_29 PF13555.1 EME30487.1 - 0.00016 21.1 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF948 PF06103.6 EME30487.1 - 0.00093 19.0 0.4 0.00093 19.0 0.3 6.6 6 2 1 7 7 7 1 Bacterial protein of unknown function (DUF948) AAA_21 PF13304.1 EME30487.1 - 0.0043 17.0 9.6 0.0086 16.0 0.0 3.7 3 2 0 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 EME30487.1 - 0.018 14.2 19.8 0.37 9.9 0.2 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EME30487.1 - 0.024 14.5 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME30487.1 - 0.041 13.6 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_13 PF13166.1 EME30487.1 - 0.27 9.6 79.9 0.14 10.5 7.3 5.1 3 2 2 5 5 5 0 AAA domain NPV_P10 PF05531.7 EME30487.1 - 0.67 10.2 34.3 0.39 10.9 0.2 6.8 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EME30487.1 - 2.4 8.1 38.2 0.082 12.8 0.3 7.8 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) AhpC-TSA PF00578.16 EME30488.1 - 9.5e-29 99.6 0.0 1.4e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME30488.1 - 1.3e-11 44.2 0.0 2.5e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Redoxin Sld5 PF05916.6 EME30489.1 - 0.0057 16.9 0.9 0.013 15.8 0.7 1.6 1 1 0 1 1 1 1 GINS complex protein FTA4 PF13093.1 EME30489.1 - 0.018 14.5 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF479 PF04336.7 EME30489.1 - 0.077 13.1 0.4 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF479 zf-RING_3 PF14369.1 EME30490.1 - 0.041 13.8 0.1 0.041 13.8 0.1 3.4 2 1 3 5 5 5 0 zinc-finger DnaJ_CXXCXGXG PF00684.14 EME30490.1 - 2.5 8.2 18.1 5.5 7.1 4.7 3.6 2 1 1 3 3 3 0 DnaJ central domain Exo_endo_phos PF03372.18 EME30491.1 - 1.2e-14 54.8 0.0 1.9e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tetraspannin PF00335.15 EME30491.1 - 0.0019 17.5 3.1 0.003 16.8 2.1 1.3 1 0 0 1 1 1 1 Tetraspanin family EphA2_TM PF14575.1 EME30491.1 - 0.03 14.6 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TPT PF03151.11 EME30492.1 - 4.3e-33 114.1 9.0 4.3e-33 114.1 6.2 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME30492.1 - 3.1e-12 46.6 25.9 5.1e-06 26.5 7.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EME30492.1 - 8.9e-07 28.1 15.7 5e-06 25.6 10.9 1.9 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EME30492.1 - 0.007 16.5 4.7 0.007 16.5 3.3 3.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter ACOX PF01756.14 EME30493.1 - 7.5e-19 67.8 0.2 1.3e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EME30493.1 - 3.7e-12 45.5 0.1 7.7e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EME30493.1 - 2.6e-07 30.9 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.11 EME30493.1 - 7.6e-07 29.6 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EME30493.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 EME30494.1 - 7.5e-19 67.8 0.2 1.3e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EME30494.1 - 3.7e-12 45.5 0.1 7.7e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EME30494.1 - 2.6e-07 30.9 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.11 EME30494.1 - 7.6e-07 29.6 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EME30494.1 - 0.0015 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NTP_transf_2 PF01909.18 EME30495.1 - 4.5e-15 55.7 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EME30495.1 - 6.1e-11 42.1 0.6 1.7e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase MAP1B_neuraxin PF00414.12 EME30495.1 - 0.048 13.0 0.5 0.12 11.7 0.3 1.7 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat DUF1759 PF03564.10 EME30495.1 - 0.17 11.6 1.6 16 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) PAP2 PF01569.16 EME30496.1 - 0.13 11.9 2.0 0.31 10.7 1.4 1.6 1 1 0 1 1 1 0 PAP2 superfamily DDOST_48kD PF03345.9 EME30497.1 - 1.8e-102 343.0 0.0 2e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ALO PF04030.9 EME30498.1 - 9.5e-94 313.7 4.1 1.3e-93 313.3 2.8 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EME30498.1 - 1.4e-31 108.7 0.0 2e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.1 EME30498.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 SIS domain zf-RING_4 PF14570.1 EME30499.1 - 7.4e-17 60.6 10.8 1.5e-16 59.7 7.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EME30499.1 - 6e-05 22.6 6.9 0.00013 21.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EME30499.1 - 0.0005 19.7 3.4 0.0017 18.0 2.4 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EME30499.1 - 0.35 10.5 11.9 1.1 8.9 8.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME30499.1 - 0.85 9.5 12.7 2 8.3 8.1 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EME30499.1 - 0.9 9.2 6.6 2.6 7.7 4.6 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 EME30499.1 - 2.7 7.7 8.5 7.4 6.3 5.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain ECH_C PF13766.1 EME30500.1 - 4.9e-39 133.1 1.3 8.3e-39 132.3 0.9 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EME30500.1 - 1e-25 90.2 0.0 7.4e-24 84.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Proteasome PF00227.21 EME30502.1 - 1.8e-53 180.6 0.2 2.2e-53 180.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME30502.1 - 8e-14 50.6 0.3 1.6e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF211 PF02680.9 EME30502.1 - 0.032 14.0 0.3 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 zf-RING_6 PF14835.1 EME30503.1 - 6.1e-09 35.5 9.0 1.3e-08 34.4 6.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EME30503.1 - 2.2e-07 30.5 15.4 5.4e-07 29.2 10.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain BRCT PF00533.21 EME30503.1 - 2.8e-06 27.3 0.2 5.4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-RING_2 PF13639.1 EME30503.1 - 4.5e-06 26.4 16.0 4.5e-06 26.4 11.1 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EME30503.1 - 0.00016 21.2 18.4 0.00016 21.2 12.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME30503.1 - 0.00018 21.4 18.4 0.00018 21.4 12.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30503.1 - 0.00043 19.9 13.5 0.0014 18.2 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PTCB-BRCT PF12738.2 EME30503.1 - 0.031 14.1 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 twin BRCT domain zf-Nse PF11789.3 EME30503.1 - 0.27 10.7 11.1 0.56 9.7 7.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EME30503.1 - 0.34 10.8 17.2 1.4 8.8 11.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME30503.1 - 1.5 8.6 12.6 0.59 9.8 5.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger FBPase PF00316.15 EME30504.1 - 1e-27 96.8 0.0 1.7e-27 96.1 0.0 1.4 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase Myb_DNA-binding PF00249.26 EME30505.1 - 1.4e-45 153.1 12.5 3.6e-15 55.7 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME30505.1 - 1.9e-34 117.5 15.3 2.3e-15 56.4 0.7 4.6 2 1 3 5 5 5 3 Myb-like DNA-binding domain PC-Esterase PF13839.1 EME30506.1 - 0.00012 21.9 0.0 0.00029 20.7 0.0 1.6 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PFK PF00365.15 EME30507.1 - 2.5e-33 115.2 2.0 3.7e-33 114.6 1.4 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 EME30507.1 - 0.023 13.4 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase PFK PF00365.15 EME30508.1 - 2.5e-33 115.2 2.0 3.8e-33 114.6 1.4 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 EME30508.1 - 0.023 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase WD40 PF00400.27 EME30509.1 - 1.1e-06 28.2 3.3 0.15 11.9 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat SMC_Nse1 PF07574.8 EME30511.1 - 2.1e-14 53.6 6.3 1.5e-11 44.3 1.2 2.0 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex SelB-wing_2 PF09106.6 EME30511.1 - 0.022 14.6 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix BDM PF10684.4 EME30511.1 - 0.041 14.1 0.6 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein DUF3349 PF11829.3 EME30511.1 - 0.11 12.9 0.6 0.62 10.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) DUF4484 PF14831.1 EME30511.1 - 0.32 11.0 4.2 5.1 7.1 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4484) Sel1 PF08238.7 EME30512.1 - 8.2e-12 45.3 3.8 4.7e-05 23.8 0.0 3.3 2 1 1 3 3 3 3 Sel1 repeat CS PF04969.11 EME30512.1 - 1.4e-05 25.5 2.8 1.8e-05 25.1 0.4 2.2 2 0 0 2 2 2 1 CS domain DUF1824 PF08854.5 EME30512.1 - 0.012 15.2 0.1 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) TPR_11 PF13414.1 EME30512.1 - 0.023 14.3 0.3 0.054 13.1 0.1 1.8 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EME30512.1 - 0.073 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME30512.1 - 0.089 13.2 1.0 16 6.2 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME30512.1 - 0.098 12.9 0.5 0.51 10.6 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DER1 PF04511.10 EME30513.1 - 5.1e-43 146.8 7.5 6.1e-43 146.6 5.2 1.1 1 0 0 1 1 1 1 Der1-like family Lactamase_B PF00753.22 EME30514.1 - 9e-20 71.1 3.2 1.2e-19 70.6 2.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME30514.1 - 0.00031 20.3 0.3 0.00061 19.3 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME30514.1 - 0.011 15.3 0.7 0.017 14.8 0.5 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain COPI_assoc PF08507.5 EME30515.1 - 4.9e-15 55.4 7.1 6e-15 55.1 4.9 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2178 PF09946.4 EME30515.1 - 0.045 13.5 1.3 0.045 13.5 0.9 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Pex24p PF06398.6 EME30515.1 - 7.9 5.1 10.1 18 3.9 6.9 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Aminotran_1_2 PF00155.16 EME30516.1 - 4.2e-59 200.3 0.0 5.3e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME30516.1 - 6e-07 28.5 0.0 9.9e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME30516.1 - 6.2e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EME30516.1 - 0.00028 19.2 0.0 0.00048 18.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME30516.1 - 0.00033 19.8 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 EME30516.1 - 0.016 13.7 0.0 0.035 12.6 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NTP_transferase PF00483.18 EME30517.1 - 3.7e-26 91.9 0.0 5.3e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EME30517.1 - 4.4e-09 36.6 0.0 8.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EME30517.1 - 6.1e-08 31.8 10.2 1.8e-05 24.0 0.6 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 EME30517.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase PI31_Prot_C PF08577.6 EME30518.1 - 3.2e-10 40.4 10.3 3.2e-10 40.4 7.1 2.2 2 0 0 2 2 2 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 EME30518.1 - 5.9e-08 32.4 0.0 8.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal AAA PF00004.24 EME30519.1 - 4.6e-42 143.3 0.0 9.9e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME30519.1 - 2.4e-06 27.7 0.0 0.00018 21.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME30519.1 - 3.3e-06 26.8 0.1 2.5e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME30519.1 - 2.3e-05 24.4 0.0 5.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EME30519.1 - 3.7e-05 23.6 0.0 0.0001 22.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EME30519.1 - 0.00017 22.3 0.1 0.00036 21.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EME30519.1 - 0.00035 19.5 0.0 0.00065 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EME30519.1 - 0.00041 19.4 0.0 0.0011 18.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME30519.1 - 0.00073 19.2 0.2 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EME30519.1 - 0.002 18.0 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME30519.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME30519.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME30519.1 - 0.0032 16.9 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EME30519.1 - 0.0037 17.4 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EME30519.1 - 0.0071 16.6 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME30519.1 - 0.0078 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 EME30519.1 - 0.0079 15.9 0.0 0.4 10.3 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase Histone PF00125.19 EME30519.1 - 0.009 16.1 0.1 0.037 14.1 0.1 2.1 2 0 0 2 2 1 1 Core histone H2A/H2B/H3/H4 TIP49 PF06068.8 EME30519.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EME30519.1 - 0.013 14.7 0.1 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EME30519.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EME30519.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME30519.1 - 0.049 13.0 0.1 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME30519.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EME30519.1 - 0.086 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EME30519.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EME30519.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EME30519.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ADK PF00406.17 EME30520.1 - 7.7e-50 168.6 0.0 1.3e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase Dpy-30 PF05186.8 EME30520.1 - 1.3e-14 53.3 0.2 2.1e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif AAA_18 PF13238.1 EME30520.1 - 3.2e-09 37.1 0.1 9e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME30520.1 - 5.3e-08 33.7 0.0 2.6e-07 31.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EME30520.1 - 7.6e-08 31.9 0.5 0.0022 17.3 0.0 2.6 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EME30520.1 - 2.7e-06 27.2 0.0 9.6e-06 25.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain NDK PF00334.14 EME30520.1 - 0.0039 16.9 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Zeta_toxin PF06414.7 EME30520.1 - 0.014 14.4 0.3 0.12 11.4 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin dNK PF01712.14 EME30520.1 - 0.031 14.1 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase Abdominal-A PF12407.3 EME30520.1 - 0.24 10.9 2.9 0.53 9.8 2.0 1.6 1 0 0 1 1 1 0 Homeobox protein Chorismate_synt PF01264.16 EME30521.1 - 2.4e-146 486.6 0.8 2.8e-146 486.4 0.6 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3326 PF11805.3 EME30522.1 - 1.4e-115 385.6 0.0 1.8e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3326) BRK PF07533.11 EME30523.1 - 6.3e-09 35.1 0.1 0.0021 17.4 0.0 2.5 2 0 0 2 2 2 2 BRK domain Img2 PF05046.9 EME30523.1 - 0.0021 18.2 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial large subunit ribosomal protein (Img2) UMP1 PF05348.6 EME30523.1 - 0.0085 16.0 0.1 5.8 6.8 0.0 3.2 3 0 0 3 3 3 1 Proteasome maturation factor UMP1 Oxidored_q6 PF01058.17 EME30524.1 - 4.2e-23 81.4 0.1 5.5e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sec63 PF02889.11 EME30525.1 - 4.7e-112 374.2 8.7 4e-74 249.6 0.1 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EME30525.1 - 3e-51 173.2 0.2 3.8e-26 91.5 0.2 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EME30525.1 - 5.4e-19 68.7 3.3 6.4e-11 42.4 0.1 3.2 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME30525.1 - 3e-17 62.2 0.0 3.5e-08 33.1 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PhoH PF02562.11 EME30525.1 - 2.8e-05 23.4 0.1 0.033 13.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 EME30525.1 - 7.6e-05 22.8 7.2 0.25 11.5 0.1 5.1 5 1 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EME30525.1 - 0.00012 21.5 0.7 0.097 12.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EME30525.1 - 0.00014 20.8 0.0 0.33 9.8 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 EME30525.1 - 0.00046 19.8 0.0 0.062 13.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EME30525.1 - 0.0011 18.2 9.6 0.0042 16.4 0.3 3.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.12 EME30525.1 - 0.0035 16.7 0.3 3.1 7.2 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_10 PF12846.2 EME30525.1 - 0.036 13.5 1.4 29 3.9 0.0 4.3 5 0 0 5 5 5 0 AAA-like domain RII_binding_1 PF10522.4 EME30525.1 - 0.081 13.0 0.5 0.57 10.5 0.0 2.8 3 0 0 3 3 1 0 RII binding domain HBS1_N PF08938.5 EME30525.1 - 0.21 11.7 2.7 0.62 10.2 1.8 1.8 1 0 0 1 1 1 0 HBS1 N-terminus DUF1759 PF03564.10 EME30525.1 - 0.8 9.5 7.0 0.44 10.3 0.2 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF1759) AAA PF00004.24 EME30525.1 - 5.8 7.1 6.2 86 3.3 0.5 4.4 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Lipase_GDSL_2 PF13472.1 EME30526.1 - 3.7e-07 30.4 0.0 3.9e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME30526.1 - 0.0023 17.8 0.1 0.021 14.6 0.1 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1792 PF08759.6 EME30526.1 - 0.005 16.4 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1792) DUF1644 PF07800.7 EME30526.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) UCR_6-4kD PF08997.5 EME30527.1 - 0.015 15.0 0.2 0.02 14.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein LBP_BPI_CETP PF01273.20 EME30528.1 - 1.5e-10 40.6 0.1 2.5e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain CUE PF02845.11 EME30528.1 - 0.059 12.8 0.1 0.26 10.8 0.1 2.1 1 0 0 1 1 1 0 CUE domain Methyltransf_21 PF05050.7 EME30529.1 - 1.9e-08 34.4 0.2 3.2e-08 33.7 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain Prefoldin_2 PF01920.15 EME30530.1 - 2.1e-10 40.3 5.3 2.6e-10 40.0 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1825 PF08855.5 EME30530.1 - 0.029 14.3 1.9 0.045 13.7 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) Sipho_Gp157 PF05565.6 EME30530.1 - 0.12 11.9 1.9 0.26 10.8 1.3 1.5 1 1 0 1 1 1 0 Siphovirus Gp157 Cep57_CLD_2 PF14197.1 EME30530.1 - 0.17 11.8 5.5 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DASH_Dad3 PF08656.5 EME30530.1 - 0.2 11.3 3.0 1.7 8.3 0.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 priB_priC PF07445.7 EME30530.1 - 0.36 10.2 5.8 0.44 10.0 4.0 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC FlxA PF14282.1 EME30530.1 - 1.4 8.8 9.0 1.2 9.1 1.5 2.2 1 1 0 2 2 2 0 FlxA-like protein CENP-Q PF13094.1 EME30530.1 - 1.8 8.5 6.0 1.1 9.2 1.4 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Med9 PF07544.8 EME30530.1 - 2.6 7.8 8.9 7.5 6.3 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 EME30530.1 - 3.7 7.3 8.1 2.2 8.0 2.0 2.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EME30530.1 - 4 6.9 11.0 17 4.9 0.4 2.0 1 1 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 EME30531.1 - 3.7e-29 101.6 29.5 5.9e-15 54.7 6.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME30531.1 - 7.9e-15 54.4 32.2 7.9e-15 54.4 22.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DAHP_synth_2 PF01474.11 EME30532.1 - 1.6e-192 639.7 0.0 1.9e-192 639.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family ECH PF00378.15 EME30533.1 - 3.7e-77 258.7 2.6 4.5e-77 258.4 1.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EME30533.1 - 0.00017 21.3 0.5 0.0083 15.9 0.0 2.5 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 EME30533.1 - 0.0041 17.2 0.2 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Hydant_A_N PF05378.8 EME30533.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region SDH_sah PF01972.11 EME30533.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase zf-H2C2_2 PF13465.1 EME30534.1 - 6.4e-15 54.6 19.8 2.3e-07 30.7 0.6 5.2 5 0 0 5 5 5 3 Zinc-finger double domain FHA PF00498.21 EME30534.1 - 2.3e-14 53.2 0.0 6.3e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.21 EME30534.1 - 3.5e-14 52.1 19.8 0.0033 17.6 0.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME30534.1 - 3e-08 33.4 21.6 0.018 15.3 0.4 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EME30534.1 - 7.6e-06 25.9 9.7 0.085 13.0 0.7 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EME30534.1 - 3.2e-05 23.6 9.7 0.0098 15.7 1.1 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger GAGA PF09237.6 EME30534.1 - 0.0022 17.5 2.5 0.25 10.9 0.6 2.6 1 1 1 2 2 2 2 GAGA factor zf-C2H2_jaz PF12171.3 EME30534.1 - 0.066 13.3 15.0 0.22 11.7 0.6 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CAF1 PF04857.15 EME30535.1 - 8.4e-23 81.0 2.2 8.6e-20 71.1 0.0 3.2 3 1 0 3 3 3 2 CAF1 family ribonuclease 3Beta_HSD PF01073.14 EME30536.1 - 1.5e-69 233.7 0.1 1.8e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME30536.1 - 1.1e-36 126.4 0.1 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME30536.1 - 1.6e-20 73.1 0.3 6.7e-17 61.2 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EME30536.1 - 1.2e-17 63.8 0.0 1.6e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME30536.1 - 2.3e-14 53.8 0.0 3.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME30536.1 - 1.1e-09 37.6 0.7 2.4e-09 36.5 0.5 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EME30536.1 - 1.1e-06 28.6 0.7 2.2e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EME30536.1 - 6.2e-05 22.3 0.6 8.4e-05 21.9 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EME30536.1 - 0.00038 20.7 0.1 0.00064 20.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EME30536.1 - 0.0044 16.7 1.2 0.017 14.7 0.8 1.8 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EME30536.1 - 0.014 14.4 0.2 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 EME30536.1 - 0.087 12.6 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 EME30536.1 - 0.093 12.6 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HA2 PF04408.18 EME30537.1 - 4.8e-25 87.5 1.5 3.9e-24 84.6 0.0 3.1 4 0 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EME30537.1 - 7.1e-24 83.8 0.0 1.8e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EME30537.1 - 2.4e-13 49.7 0.0 7.1e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME30537.1 - 3.6e-08 33.0 0.1 8.5e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME30537.1 - 4.6e-06 26.8 0.1 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EME30537.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EME30537.1 - 0.00038 19.4 0.0 0.00088 18.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EME30537.1 - 0.00056 19.8 0.2 0.0031 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EME30537.1 - 0.0058 16.0 0.1 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EME30537.1 - 0.0079 16.2 0.0 0.064 13.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.10 EME30537.1 - 0.01 15.6 3.3 0.78 9.5 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EME30537.1 - 0.014 15.6 2.6 0.017 15.3 0.0 2.5 3 0 0 3 3 2 0 ABC transporter AAA_19 PF13245.1 EME30537.1 - 0.015 14.9 0.0 0.047 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 EME30537.1 - 0.024 15.1 0.0 0.098 13.1 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EME30537.1 - 0.027 14.1 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EME30537.1 - 0.043 14.1 1.1 0.18 12.1 0.0 2.7 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EME30537.1 - 0.05 13.9 0.0 0.05 13.9 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_29 PF13555.1 EME30537.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Profilin PF00235.14 EME30538.1 - 2.4e-35 121.2 0.3 2.7e-35 121.1 0.2 1.0 1 0 0 1 1 1 1 Profilin Glyco_transf_20 PF00982.16 EME30539.1 - 1.8e-163 544.4 0.0 2.3e-163 544.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME30539.1 - 1.4e-50 171.3 0.0 2.7e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EME30539.1 - 5.6e-06 26.1 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EME30539.1 - 0.0018 17.6 0.1 0.0078 15.5 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HTH_25 PF13413.1 EME30539.1 - 0.0088 15.6 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain PXA PF02194.10 EME30539.1 - 0.017 14.7 0.3 4.7 6.7 0.0 2.7 2 0 0 2 2 2 0 PXA domain ATP-grasp_2 PF08442.5 EME30540.1 - 8.3e-70 234.2 2.9 8.3e-70 234.2 2.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EME30540.1 - 1.9e-25 89.2 3.3 1.9e-25 89.2 2.3 2.5 3 0 0 3 3 3 1 CoA-ligase ATP-grasp_5 PF13549.1 EME30540.1 - 6e-18 64.8 0.4 6e-18 64.8 0.3 1.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EME30540.1 - 1.1e-06 28.2 3.4 3.6e-06 26.5 0.1 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 EME30540.1 - 5.8e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EME30540.1 - 1.5e-05 24.4 0.2 3.9e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EME30540.1 - 0.00036 19.3 0.0 0.00067 18.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 EME30540.1 - 0.00049 19.7 0.6 0.00049 19.7 0.4 2.5 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 EME30540.1 - 0.026 13.8 1.1 0.079 12.3 0.1 2.2 2 2 0 2 2 2 0 ATP-grasp domain DUF552 PF04472.7 EME30540.1 - 0.077 12.9 0.5 3.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF552) GIDA PF01134.17 EME30543.1 - 4.3e-154 513.1 0.0 6.2e-154 512.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EME30543.1 - 6.6e-26 90.1 0.0 2.1e-25 88.5 0.0 2.0 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 EME30543.1 - 1.2e-06 27.9 2.6 2.4e-06 26.8 1.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME30543.1 - 5.8e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME30543.1 - 0.00042 19.2 3.8 0.0015 17.5 1.6 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EME30543.1 - 0.012 14.5 1.9 0.57 9.0 0.5 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EME30543.1 - 0.023 13.2 3.7 0.31 9.4 0.6 2.9 3 0 0 3 3 3 0 HI0933-like protein ThiF PF00899.16 EME30543.1 - 0.032 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 EME30543.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.17 EME30545.1 - 3e-24 85.8 0.0 8.5e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME30545.1 - 1.6e-14 53.6 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.14 EME30545.1 - 0.0019 17.3 0.0 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EME30545.1 - 0.0089 15.9 0.3 0.089 12.7 0.1 2.4 1 1 2 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EME30545.1 - 0.014 15.3 0.1 0.045 13.6 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 EME30545.1 - 0.095 12.5 0.5 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 ThiF family KLRAQ PF10205.4 EME30546.1 - 0.35 10.9 3.0 0.83 9.7 0.1 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Cnd2 PF05786.9 EME30547.1 - 1.7e-106 357.5 19.1 2.4e-106 356.9 13.3 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF2407_C PF13373.1 EME30548.1 - 1.8e-26 92.7 0.2 3.1e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 EME30548.1 - 1.4e-11 43.6 0.3 4.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 EME30548.1 - 8.9e-07 28.5 0.0 1.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EME30548.1 - 5.9e-05 22.9 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FERM_N PF09379.5 EME30548.1 - 0.0062 16.5 0.1 0.034 14.1 0.1 2.1 2 0 0 2 2 2 1 FERM N-terminal domain DUF2407 PF10302.4 EME30548.1 - 0.028 14.6 1.6 0.21 11.7 1.1 2.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain BioY PF02632.9 EME30548.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 BioY family DUF4131 PF13567.1 EME30548.1 - 0.26 10.7 1.3 2.4 7.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2407_C PF13373.1 EME30549.1 - 1.7e-26 92.8 0.2 2.8e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 EME30549.1 - 1.7e-13 49.7 0.2 6e-13 47.9 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EME30549.1 - 7.1e-09 35.2 0.1 1.1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EME30549.1 - 5.8e-06 26.1 0.1 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME30549.1 - 8.5e-06 25.8 1.2 2.5e-05 24.3 0.9 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain FERM_N PF09379.5 EME30549.1 - 0.0066 16.4 0.1 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain TUG-UBL1 PF11470.3 EME30549.1 - 0.029 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG BioY PF02632.9 EME30549.1 - 0.07 12.7 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 BioY family Ubiquitin_2 PF14560.1 EME30549.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF938 PF06080.7 EME30550.1 - 1.8e-50 171.3 0.0 2e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 EME30550.1 - 1.5e-09 38.3 0.0 2.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME30550.1 - 9e-09 35.2 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30550.1 - 3e-08 34.0 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30550.1 - 2.6e-05 24.5 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30550.1 - 2.7e-05 24.5 0.0 6.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME30550.1 - 0.00024 21.0 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME30550.1 - 0.00026 20.4 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EME30550.1 - 0.00029 19.9 0.0 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EME30550.1 - 0.0028 16.7 0.0 0.01 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase KH_3 PF13014.1 EME30551.1 - 0.0042 16.7 0.0 0.015 14.9 0.0 2.0 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EME30551.1 - 0.0098 15.5 0.0 0.027 14.0 0.0 1.8 1 1 1 2 2 2 1 KH domain KH_4 PF13083.1 EME30551.1 - 0.01 15.4 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 KH domain KH_1 PF00013.24 EME30552.1 - 3.9e-09 36.0 0.0 8e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EME30552.1 - 3.3e-05 23.4 0.6 7.5e-05 22.2 0.4 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 EME30552.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 KH domain Retrotrans_gag PF03732.12 EME30553.1 - 0.093 12.8 0.3 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Sec6 PF06046.8 EME30554.1 - 3.7e-35 121.0 0.8 3.3e-33 114.6 0.2 3.0 2 1 0 2 2 2 2 Exocyst complex component Sec6 eIF-3c_N PF05470.7 EME30557.1 - 6.6e-142 473.6 24.5 4.9e-141 470.7 17.0 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EME30557.1 - 8.5e-12 45.3 0.3 3.9e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain ChaB PF06150.7 EME30557.1 - 0.022 14.5 0.7 4.8 7.0 0.3 3.1 2 0 0 2 2 2 0 ChaB Acetyltransf_1 PF00583.19 EME30558.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EME30558.1 - 0.00087 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME30558.1 - 0.0044 17.1 0.0 0.0062 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME30558.1 - 0.0068 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME30558.1 - 0.015 15.4 0.1 0.061 13.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2826 PF11442.3 EME30559.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) HCO3_cotransp PF00955.16 EME30561.1 - 5.8e-79 266.0 21.7 8.7e-44 150.0 4.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family Band_3_cyto PF07565.8 EME30561.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S9 PF00326.16 EME30562.1 - 0.0027 16.9 0.1 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME30562.1 - 0.0099 15.6 0.0 0.03 14.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family RRM_1 PF00076.17 EME30563.1 - 1e-38 130.7 0.3 1.3e-18 66.3 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30563.1 - 8.6e-34 115.3 0.0 1.1e-11 44.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30563.1 - 3.1e-20 71.7 0.0 1.7e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME30564.1 - 8.8e-39 130.9 0.3 1.3e-18 66.3 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30564.1 - 7.5e-34 115.5 0.0 1.1e-11 44.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30564.1 - 2.8e-20 71.8 0.0 1.7e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPD PF14811.1 EME30565.1 - 5.8e-40 136.0 0.0 1e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif K-box PF01486.12 EME30566.1 - 0.072 12.8 0.0 0.39 10.5 0.0 2.2 1 1 1 2 2 2 0 K-box region SRP40_C PF05022.7 EME30567.1 - 3.1e-22 78.8 4.5 9.3e-22 77.3 3.1 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 EME30567.1 - 4.3e-06 26.2 0.0 7.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 LisH DUF4651 PF15513.1 EME30567.1 - 0.086 12.3 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) SRP40_C PF05022.7 EME30568.1 - 2.9e-22 78.9 4.5 8.8e-22 77.3 3.1 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 EME30568.1 - 4.1e-06 26.3 0.0 7.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 LisH DUF4651 PF15513.1 EME30568.1 - 0.083 12.3 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) DUF563 PF04577.9 EME30569.1 - 6.9e-15 55.5 0.1 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glycos_transf_2 PF00535.21 EME30570.1 - 4.1e-35 120.9 0.0 5.1e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME30570.1 - 7.2e-14 52.1 0.0 1.4e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EME30570.1 - 4.8e-07 29.1 0.0 6.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME30570.1 - 2.1e-06 27.1 0.0 3.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 zf-SNAP50_C PF12251.3 EME30571.1 - 1.1e-19 70.5 9.4 2e-19 69.7 6.5 1.4 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-SNAP50_C PF12251.3 EME30572.1 - 4.7e-22 78.3 8.9 6.9e-22 77.7 6.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal RB_A PF01858.12 EME30573.1 - 3e-26 92.2 0.3 6.6e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain RB_B PF01857.15 EME30573.1 - 1.6e-21 76.2 6.0 4.4e-21 74.7 4.1 1.8 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain RhoGAP PF00620.22 EME30574.1 - 0.0027 17.3 0.0 0.009 15.6 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain RD3 PF14473.1 EME30574.1 - 0.0063 15.9 0.0 0.022 14.2 0.0 1.9 1 0 0 1 1 1 1 RD3 protein HD_4 PF13328.1 EME30575.1 - 5.6e-47 159.2 0.2 3.9e-46 156.5 0.0 2.4 2 1 0 2 2 2 1 HD domain RelA_SpoT PF04607.12 EME30575.1 - 1.4e-24 86.2 0.0 7.8e-19 67.7 0.0 2.9 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins TGS PF02824.16 EME30575.1 - 7.8e-24 83.2 0.0 2.1e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.1 EME30575.1 - 1e-08 35.3 0.0 2.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain HD PF01966.17 EME30575.1 - 2.4e-07 30.7 0.1 9.2e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 HD domain ACT PF01842.20 EME30575.1 - 2.9e-06 26.6 0.1 1.1e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 ACT domain DPM3 PF08285.6 EME30576.1 - 2.5e-11 43.2 0.0 2.8e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2040 PF09745.4 EME30578.1 - 1.5e-23 82.9 21.2 1.5e-23 82.9 14.7 2.3 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF3949 PF13133.1 EME30578.1 - 0.84 9.9 4.8 1.1 9.4 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3949) DUF4633 PF15464.1 EME30578.1 - 4.1 7.2 13.8 0.12 12.1 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) RRM_1 PF00076.17 EME30579.1 - 3.3e-12 45.8 0.0 0.00017 21.1 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30579.1 - 5.7e-11 42.2 0.0 4.7e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30579.1 - 2e-07 30.7 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4339 PF14237.1 EME30579.1 - 1.9e-06 27.3 0.0 5.4e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Peptidase_S49_N PF08496.5 EME30579.1 - 0.39 10.5 3.2 0.84 9.4 2.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sel1 PF08238.7 EME30580.1 - 5.1e-22 77.8 19.5 1.1e-05 25.9 0.0 10.1 10 1 0 10 10 10 5 Sel1 repeat TPR_7 PF13176.1 EME30580.1 - 0.0003 20.3 2.4 3.8 7.5 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME30580.1 - 0.0018 18.5 16.4 0.25 11.7 0.4 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME30580.1 - 0.002 17.6 12.5 0.16 11.6 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME30580.1 - 0.0024 17.6 19.1 0.024 14.5 0.1 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME30580.1 - 0.0075 15.8 9.7 0.013 15.0 0.1 3.8 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.1 EME30580.1 - 0.014 16.0 10.7 4.4 8.0 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME30580.1 - 0.056 13.3 5.5 1.3 8.9 0.1 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME30580.1 - 0.13 12.0 12.2 55 3.8 0.1 6.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME30580.1 - 0.39 11.2 8.9 18 6.0 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.24 EME30581.1 - 3.5e-87 289.3 0.0 5.2e-47 159.3 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME30581.1 - 8e-16 57.7 0.0 6.3e-08 31.9 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME30581.1 - 5.5e-13 49.8 0.0 1.6e-05 25.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME30581.1 - 5.4e-12 45.9 0.4 0.0011 19.1 0.1 4.9 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EME30581.1 - 7.4e-11 42.3 7.1 9.2e-05 22.5 0.0 5.1 4 2 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 EME30581.1 - 4.6e-10 39.5 0.0 0.00056 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EME30581.1 - 2.4e-09 37.3 0.0 0.0018 18.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EME30581.1 - 2.4e-09 37.1 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME30581.1 - 5.8e-09 35.8 0.6 0.0014 18.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EME30581.1 - 2e-08 34.6 0.0 0.01 16.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.7 EME30581.1 - 3.3e-08 32.8 0.0 0.00014 21.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EME30581.1 - 3.1e-07 29.9 0.0 0.0063 15.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EME30581.1 - 3.7e-07 30.2 0.0 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 EME30581.1 - 7.7e-07 28.1 0.1 0.0084 14.8 0.0 2.8 2 1 1 3 3 3 2 TIP49 C-terminus AAA_28 PF13521.1 EME30581.1 - 8.8e-07 29.0 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EME30581.1 - 9.5e-07 29.1 0.0 0.041 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME30581.1 - 1.8e-06 27.4 0.1 0.21 10.9 0.0 3.4 2 1 1 3 3 3 2 AAA domain NACHT PF05729.7 EME30581.1 - 1.8e-06 27.6 2.0 0.11 12.1 0.0 3.7 4 0 0 4 4 3 2 NACHT domain Rad17 PF03215.10 EME30581.1 - 3.4e-06 26.0 0.0 0.02 13.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EME30581.1 - 6.5e-06 25.8 4.4 0.0065 16.2 0.2 3.5 3 1 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EME30581.1 - 9.9e-06 24.8 0.9 0.025 13.7 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME30581.1 - 1.2e-05 24.9 0.1 0.19 11.1 0.0 3.2 4 0 0 4 4 3 2 Sigma-54 interaction domain KaiC PF06745.8 EME30581.1 - 1.3e-05 24.4 0.1 0.33 10.0 0.0 3.3 2 1 1 3 3 3 2 KaiC Arch_ATPase PF01637.13 EME30581.1 - 1.6e-05 24.7 0.7 0.33 10.6 0.0 4.4 3 2 2 5 5 5 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EME30581.1 - 2e-05 24.6 0.0 0.29 11.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EME30581.1 - 0.00011 21.5 0.1 0.46 9.6 0.0 2.9 3 0 0 3 3 3 2 PhoH-like protein Vps4_C PF09336.5 EME30581.1 - 0.00012 21.9 0.2 0.016 15.0 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 EME30581.1 - 0.0002 21.0 0.3 0.072 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EME30581.1 - 0.00026 19.9 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 EME30581.1 - 0.00087 18.8 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EME30581.1 - 0.00094 18.7 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EME30581.1 - 0.0013 18.2 0.1 0.7 9.3 0.0 2.8 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EME30581.1 - 0.0013 18.4 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EME30581.1 - 0.0017 17.9 0.0 0.53 9.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 EME30581.1 - 0.0036 17.2 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.12 EME30581.1 - 0.0066 15.3 0.0 0.21 10.4 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.17 EME30581.1 - 0.0093 15.8 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase IPT PF01745.11 EME30581.1 - 0.012 14.7 0.1 3 6.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_23 PF13476.1 EME30581.1 - 0.021 15.1 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EME30581.1 - 0.048 12.8 0.0 8.3 5.5 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 EME30581.1 - 0.053 12.4 0.0 1.3 7.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EME30581.1 - 0.065 12.6 0.9 5 6.4 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain AAA_29 PF13555.1 EME30581.1 - 0.073 12.6 0.0 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.4 EME30581.1 - 0.074 11.9 0.0 13 4.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EME30581.1 - 0.086 11.7 0.0 8.8 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EME30581.1 - 0.11 12.2 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 EME30581.1 - 0.12 12.0 0.1 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein DEAD PF00270.24 EME30581.1 - 0.17 11.3 0.0 29 4.0 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase Pkinase PF00069.20 EME30582.1 - 2e-71 240.1 0.0 3.1e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30582.1 - 1.4e-44 152.1 0.0 3.3e-44 150.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30582.1 - 1.5e-06 27.4 0.0 2.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME30582.1 - 0.0035 17.1 0.0 0.72 9.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Peptidase_C97 PF05903.9 EME30583.1 - 8e-13 48.4 0.2 1.4e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EME30583.1 - 0.001 17.9 0.9 0.006 15.4 0.2 2.0 1 1 1 2 2 2 1 PUL domain CRM1_C PF08767.6 EME30583.1 - 0.059 12.2 0.3 0.19 10.5 0.1 1.8 1 1 1 2 2 2 0 CRM1 C terminal MCM PF00493.18 EME30585.1 - 1.7e-132 441.2 0.2 2.6e-132 440.6 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME30585.1 - 3.2e-21 76.0 0.1 1.4e-20 73.9 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME30585.1 - 7.1e-08 31.8 0.1 2.4e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EME30585.1 - 0.009 15.6 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME30585.1 - 0.0097 15.3 0.1 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EME30585.1 - 0.037 13.7 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) tRNA-synt_1b PF00579.20 EME30586.1 - 2.2e-76 256.8 0.0 3.1e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EME30586.1 - 0.00036 19.8 0.0 0.00075 18.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain PAP2 PF01569.16 EME30588.1 - 4.3e-10 39.3 5.2 9.3e-10 38.2 3.6 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EME30588.1 - 1.2e-05 24.8 7.4 3.1e-05 23.6 5.1 1.6 1 1 0 1 1 1 1 PAP2 superfamily TOH_N PF12549.3 EME30588.1 - 1.8 8.2 6.3 0.15 11.6 0.8 1.9 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal L6_membrane PF05805.7 EME30589.1 - 0.1 12.1 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 L6 membrane protein Otopetrin PF03189.8 EME30589.1 - 0.44 9.4 0.0 0.44 9.4 0.0 2.5 2 1 1 3 3 3 0 Otopetrin Neur_chan_memb PF02932.11 EME30589.1 - 3 7.6 6.2 10 5.9 4.3 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAP59_mtransfer PF11735.3 EME30590.1 - 1.4e-55 188.1 0.0 2.1e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_M48 PF01435.13 EME30590.1 - 4.5e-15 55.8 0.4 2.1e-14 53.6 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.6 EME30590.1 - 1.6e-05 24.0 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF955 PF06114.8 EME30590.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF955) 2C_adapt PF08793.5 EME30591.1 - 2.5e-08 33.6 0.2 0.0028 17.4 0.2 2.5 2 0 0 2 2 2 2 2-cysteine adaptor domain Mito_carr PF00153.22 EME30592.1 - 1.3e-74 245.9 1.7 4.6e-26 90.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF992 PF06186.6 EME30592.1 - 0.13 11.6 0.6 5.4 6.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF992) EMP70 PF02990.11 EME30593.1 - 3.3e-185 616.5 1.5 4.7e-185 615.9 1.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 EF1G PF00647.14 EME30594.1 - 1.7e-38 130.5 0.6 6.9e-38 128.6 0.2 2.2 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EME30594.1 - 8.1e-14 51.3 0.1 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME30594.1 - 8.2e-12 45.1 0.1 2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME30594.1 - 3.6e-11 43.1 0.0 8.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME30594.1 - 7.6e-10 38.5 0.1 2.6e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME30594.1 - 4e-07 29.9 0.0 8.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME30594.1 - 7.5e-06 26.3 0.0 2.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sugarporin_N PF11471.3 EME30594.1 - 0.0022 17.5 0.9 0.11 12.1 0.0 2.7 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension HEAT_2 PF13646.1 EME30594.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Kinesin PF00225.18 EME30595.1 - 1.6e-111 372.2 1.0 1.6e-111 372.2 0.7 2.1 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EME30595.1 - 0.0024 17.1 0.9 0.0024 17.1 0.6 2.8 3 0 0 3 3 3 1 Reovirus sigma C capsid protein HDA2-3 PF11496.3 EME30596.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Zot PF05707.7 EME30596.1 - 0.095 12.1 0.1 1 8.7 0.0 2.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) GRIP PF01465.15 EME30597.1 - 8.9e-12 44.3 0.2 3.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 GRIP domain ADIP PF11559.3 EME30597.1 - 0.0012 18.8 12.5 0.0012 18.8 8.6 9.7 3 3 5 9 9 9 3 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EME30597.1 - 0.0014 17.1 25.1 0.0014 17.1 17.4 6.1 1 1 4 5 5 5 2 AAA domain Reo_sigmaC PF04582.7 EME30597.1 - 0.0028 16.8 51.4 0.019 14.1 3.0 6.3 2 2 3 6 6 6 3 Reovirus sigma C capsid protein GAS PF13851.1 EME30597.1 - 0.0045 16.2 20.9 0.0045 16.2 14.5 8.8 4 1 4 8 8 8 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EME30597.1 - 0.0057 16.5 23.2 0.0057 16.5 16.1 11.2 2 2 6 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 EME30597.1 - 0.02 15.6 9.6 0.02 15.6 6.7 10.8 5 3 6 11 11 11 0 Occludin homology domain CHD5 PF04420.9 EME30598.1 - 0.00089 18.9 1.4 0.0012 18.5 1.0 1.1 1 0 0 1 1 1 1 CHD5-like protein Nucleoporin2 PF04096.9 EME30599.1 - 2.8e-42 143.8 0.0 4.6e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.3 EME30599.1 - 1.1e-31 110.1 0.0 2.4e-31 108.9 0.0 1.6 2 0 0 2 2 2 1 Nuclear protein 96 Nup84_Nup100 PF04121.8 EME30599.1 - 0.084 10.5 0.3 0.22 9.1 0.0 1.6 2 0 0 2 2 2 0 Nuclear pore protein 84 / 107 RNA_pol_Rpo13 PF12136.3 EME30599.1 - 1.1 8.9 14.9 0.078 12.6 1.9 2.8 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain UPF0081 PF03652.10 EME30600.1 - 5e-30 104.3 0.0 7.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) Osmo_CC PF08946.5 EME30600.1 - 0.21 11.6 1.9 0.48 10.5 1.3 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil ETF_QO PF05187.8 EME30601.1 - 0.17 11.8 1.7 0.21 11.5 0.8 1.5 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Nucleoplasmin PF03066.10 EME30602.1 - 2e-08 33.8 3.1 2e-08 33.8 2.2 3.1 1 1 1 2 2 2 1 Nucleoplasmin YL1 PF05764.8 EME30602.1 - 0.21 11.1 50.3 1.3 8.5 22.7 2.1 1 1 1 2 2 2 0 YL1 nuclear protein Utp14 PF04615.8 EME30602.1 - 3.9 5.5 50.0 4.9 5.1 34.6 1.0 1 0 0 1 1 1 0 Utp14 protein SIR2 PF02146.12 EME30603.1 - 2.4e-20 72.9 1.2 3.3e-16 59.5 0.1 2.3 1 1 1 2 2 2 2 Sir2 family DUF1948 PF09185.5 EME30603.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Sugar_tr PF00083.19 EME30604.1 - 1.4e-21 76.5 23.9 3.3e-15 55.6 7.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME30604.1 - 3.6e-13 48.9 29.5 4.8e-13 48.5 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME30604.1 - 0.00019 19.9 14.4 0.00019 19.9 10.0 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein zf-C3Hc3H PF13891.1 EME30606.1 - 0.23 11.5 1.4 8 6.6 0.2 2.6 2 0 0 2 2 2 0 Potential DNA-binding domain DUF883 PF05957.8 EME30606.1 - 1.7 9.1 3.7 2.7 8.4 0.4 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Pyr_redox_2 PF07992.9 EME30607.1 - 1.4e-17 64.2 0.0 2.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME30607.1 - 3.9e-11 43.1 0.0 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME30607.1 - 6.5e-08 31.8 0.0 0.22 10.3 0.0 3.4 3 1 0 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME30607.1 - 8.4e-06 24.9 0.0 0.00013 21.0 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EME30607.1 - 1.7e-05 24.9 0.0 0.0016 18.5 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME30607.1 - 4.4e-05 23.4 0.0 0.0095 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME30607.1 - 0.002 17.9 0.1 0.65 9.7 0.0 3.2 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME30607.1 - 0.097 11.6 0.0 15 4.4 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain Ctf8 PF09696.5 EME30608.1 - 4.5e-18 65.1 0.2 5.4e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Ctf8 Ctf8 PF09696.5 EME30609.1 - 1.1e-19 70.4 0.1 1.3e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Ctf8 PHD PF00628.24 EME30610.1 - 2.8e-05 23.6 10.3 2.8e-05 23.6 7.2 4.8 3 2 2 5 5 5 2 PHD-finger DUF2410 PF10307.4 EME30611.1 - 5.2e-13 48.8 0.1 1e-12 47.8 0.0 1.5 2 0 0 2 2 2 1 Hypothetical protein (DUF2410) HAD PF12710.2 EME30611.1 - 0.1 12.7 0.1 0.86 9.7 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_7 PF03441.9 EME30613.1 - 4.2e-83 278.7 0.0 7.6e-83 277.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME30613.1 - 4.4e-34 117.6 0.0 8.6e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF956 PF06115.6 EME30613.1 - 0.037 13.6 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF956) LXG PF04740.7 EME30614.1 - 0.034 13.9 0.9 0.034 13.9 0.6 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily FlaF PF07309.6 EME30614.1 - 0.15 11.8 2.7 0.18 11.6 0.2 2.3 1 1 0 2 2 2 0 Flagellar protein FlaF CENP-H PF05837.7 EME30614.1 - 1.8 8.7 10.5 7.7 6.7 1.9 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF3479 PF11965.3 EME30616.1 - 3.8e-15 56.0 0.0 8.4e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) P22_Cro PF14549.1 EME30616.1 - 0.11 12.2 0.4 9.1 6.0 0.0 3.4 4 0 0 4 4 4 0 DNA-binding transcriptional regulator Cro PAT1 PF09770.4 EME30617.1 - 2.2e-14 52.7 17.4 8.7e-08 30.9 0.1 3.1 1 1 1 3 3 3 3 Topoisomerase II-associated protein PAT1 tRNA-synt_2 PF00152.15 EME30619.1 - 6.7e-63 212.4 0.1 6.7e-63 212.4 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME30619.1 - 1.2e-12 47.5 0.0 2.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EME30619.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like tRNA_anti_2 PF13742.1 EME30619.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FAA_hydrolase_N PF09298.6 EME30619.1 - 0.56 10.2 3.5 1.3 9.0 2.5 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal tRNA-synt_2 PF00152.15 EME30620.1 - 8.3e-80 268.0 0.9 1.3e-79 267.3 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME30620.1 - 1.3e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EME30620.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like tRNA_anti_2 PF13742.1 EME30620.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FAA_hydrolase_N PF09298.6 EME30620.1 - 0.63 10.0 3.5 1.4 8.9 2.5 1.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Peptidase_M50 PF02163.17 EME30621.1 - 6.6e-17 61.0 0.0 1.3e-15 56.8 0.0 2.4 2 1 0 2 2 2 1 Peptidase family M50 DUF3789 PF12664.2 EME30621.1 - 1.5 8.2 7.2 5.3 6.4 5.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF406 PF04175.7 EME30622.1 - 0.017 15.5 6.0 0.055 13.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF406) DUF2638 PF10937.3 EME30622.1 - 0.33 11.9 3.9 0.18 12.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DUF217 PF02697.9 EME30622.1 - 0.91 9.8 5.6 0.27 11.5 1.1 2.1 1 1 1 2 2 2 0 Uncharacterized ACR, COG1753 Rhomboid PF01694.17 EME30623.1 - 1.3e-26 93.3 6.3 2.6e-26 92.3 4.4 1.4 1 0 0 1 1 1 1 Rhomboid family Rhomboid PF01694.17 EME30624.1 - 1.3e-26 93.3 6.3 2.5e-26 92.4 4.4 1.4 1 0 0 1 1 1 1 Rhomboid family zf-HIT PF04438.11 EME30625.1 - 1.3e-08 34.2 12.3 1.3e-08 34.2 8.5 1.7 2 0 0 2 2 2 1 HIT zinc finger ScpA_ScpB PF02616.9 EME30625.1 - 0.0062 16.1 1.0 0.025 14.1 0.1 2.1 2 0 0 2 2 2 1 ScpA/B protein SHQ1 PF04925.10 EME30625.1 - 0.012 15.0 0.6 0.035 13.5 0.4 1.8 1 1 0 1 1 1 0 SHQ1 protein zf-B_box PF00643.19 EME30625.1 - 7.6 6.5 14.2 1.4 8.8 6.7 2.1 2 0 0 2 2 2 0 B-box zinc finger GTP_EFTU PF00009.22 EME30626.1 - 1.1e-31 109.8 0.2 1.8e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME30626.1 - 1.2e-06 28.4 0.4 3e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EME30626.1 - 0.00011 21.5 0.4 0.00022 20.5 0.3 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EME30626.1 - 0.0005 20.5 0.2 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EME30626.1 - 0.00069 19.6 0.1 0.0022 18.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EME30626.1 - 0.001 18.6 0.8 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EME30626.1 - 0.0025 17.3 0.4 4.8 6.6 0.1 3.1 2 1 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF663 PF04950.7 EME30626.1 - 0.012 14.6 0.9 0.085 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF663) Septin PF00735.13 EME30626.1 - 0.033 13.1 0.2 0.13 11.2 0.0 1.9 1 1 1 2 2 2 0 Septin Aminotran_1_2 PF00155.16 EME30627.1 - 4.5e-47 160.7 0.0 5.4e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EME30627.1 - 9.5e-07 27.7 0.0 1.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Allinase Trm112p PF03966.11 EME30628.1 - 8.8e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Proteasome PF00227.21 EME30629.1 - 1.1e-60 204.1 0.1 1.5e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME30629.1 - 9.4e-15 53.6 0.1 9.4e-15 53.6 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature tRNA_lig_CPD PF08302.6 EME30629.1 - 0.087 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Nup54 PF13874.1 EME30630.1 - 6.2e-30 103.7 0.9 6.2e-30 103.7 0.6 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 CK2S PF15011.1 EME30630.1 - 0.015 15.0 5.7 0.044 13.5 1.4 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate Cnl2_NKP2 PF09447.5 EME30630.1 - 0.016 14.8 1.0 0.016 14.8 0.7 2.2 2 0 0 2 2 2 0 Cnl2/NKP2 family protein PurA PF04845.8 EME30630.1 - 0.027 13.5 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein HisKA_2 PF07568.7 EME30630.1 - 0.039 13.8 0.9 0.34 10.7 0.0 2.6 2 1 1 3 3 3 0 Histidine kinase NPV_P10 PF05531.7 EME30630.1 - 0.082 13.1 1.5 1.2 9.4 0.1 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PFK PF00365.15 EME30631.1 - 2.6e-22 79.1 0.0 3.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phosphofructokinase NIF PF03031.13 EME30632.1 - 7.5e-07 28.9 0.2 2.1e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EME30632.1 - 0.0014 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EME30632.1 - 0.092 12.0 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Exo_endo_phos PF03372.18 EME30633.1 - 1.9e-18 67.3 0.0 2.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S19e PF01090.14 EME30634.1 - 1e-54 183.7 0.0 1.1e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 EME30634.1 - 0.0023 17.6 0.9 0.0041 16.8 0.7 1.4 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Arteri_nucleo PF01481.11 EME30634.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Homeobox_KN PF05920.6 EME30635.1 - 6.8e-18 64.0 0.3 1.5e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EME30635.1 - 8.1e-10 38.1 4.2 1.5e-09 37.2 2.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EME30635.1 - 0.00019 20.4 1.4 0.0023 16.9 0.5 2.4 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez KNOX2 PF03791.8 EME30635.1 - 0.0079 15.4 3.7 0.0085 15.3 0.6 2.2 2 0 0 2 2 2 1 KNOX2 domain NAAA-beta PF15508.1 EME30635.1 - 0.062 13.6 0.3 1.2 9.5 0.1 2.1 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Acetyltransf_11 PF13720.1 EME30635.1 - 0.08 13.1 0.4 0.32 11.2 0.0 2.1 1 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ING PF12998.2 EME30635.1 - 0.98 9.7 7.4 0.4 10.9 1.6 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MCM_N PF14551.1 EME30635.1 - 1.4 9.4 4.6 5.9 7.4 3.2 2.1 1 1 0 1 1 1 0 MCM N-terminal domain YtzH PF14165.1 EME30635.1 - 2.7 8.2 8.4 8.7 6.6 4.7 2.5 1 1 0 1 1 1 0 YtzH-like protein DUF4403 PF14356.1 EME30636.1 - 0.29 9.3 3.2 0.4 8.9 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4403) DUF2884 PF11101.3 EME30636.1 - 1.2 8.4 20.0 1.5 8.1 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RHD3 PF05879.7 EME30636.1 - 1.8 6.3 14.8 2 6.2 10.2 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF445 PF04286.7 EME30636.1 - 2.7 7.4 15.3 3.1 7.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YpjP PF14005.1 EME30636.1 - 4.1 7.1 14.4 3.1 7.5 4.4 2.2 1 1 1 2 2 2 0 YpjP-like protein IGR PF09597.5 EME30636.1 - 9 6.2 6.2 2.3 8.1 0.4 2.5 1 1 2 3 3 3 0 IGR protein motif Phosphoesterase PF04185.9 EME30637.1 - 1.5e-22 80.3 9.3 1.5e-17 63.9 0.5 3.0 2 1 1 3 3 3 3 Phosphoesterase family Arf PF00025.16 EME30638.1 - 1.3e-10 40.8 0.0 1.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family CENP-M PF11111.3 EME30638.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) WD40 PF00400.27 EME30640.1 - 6.3e-27 92.4 1.5 9.8e-07 28.4 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat IKI3 PF04762.7 EME30640.1 - 0.0037 15.1 0.3 0.043 11.6 0.2 2.0 2 0 0 2 2 2 1 IKI3 family Myosin_tail_1 PF01576.14 EME30640.1 - 0.018 12.8 1.7 0.024 12.4 1.2 1.1 1 0 0 1 1 1 0 Myosin tail Cortex-I_coil PF09304.5 EME30640.1 - 0.025 14.6 1.2 0.048 13.7 0.9 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4618 PF15397.1 EME30640.1 - 0.029 13.6 0.3 0.052 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2415 PF10313.4 EME30640.1 - 0.03 14.0 0.0 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Fmp27_WPPW PF10359.4 EME30640.1 - 0.098 11.0 3.3 0.13 10.6 2.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Speriolin_N PF15058.1 EME30640.1 - 0.15 11.9 0.4 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 Speriolin N terminus DivIC PF04977.10 EME30640.1 - 3.1 7.3 6.4 1.8 8.1 2.8 1.8 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.1 EME30640.1 - 8.3 6.4 8.2 1 9.3 2.4 1.9 2 0 0 2 2 2 0 FlxA-like protein Lon_C PF05362.8 EME30641.1 - 3e-65 219.3 0.0 7.8e-65 218.0 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EME30641.1 - 1.2e-29 103.5 0.0 3.4e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EME30641.1 - 2.4e-10 40.7 0.0 6.8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EME30641.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Kua-UEV1_localn PF10520.4 EME30642.1 - 1.7e-42 145.0 2.4 1.7e-42 145.0 1.7 1.9 2 0 0 2 2 2 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain L51_S25_CI-B8 PF05047.11 EME30643.1 - 1.8e-08 33.9 0.0 2.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain adh_short PF00106.20 EME30644.1 - 1.9e-05 24.6 0.0 2.1e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EME30644.1 - 0.00028 20.9 0.0 0.00033 20.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EME30644.1 - 0.00061 18.8 0.0 0.00069 18.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EME30644.1 - 0.007 15.8 0.0 0.0075 15.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME30644.1 - 0.012 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EME30644.1 - 0.013 15.7 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME30644.1 - 0.015 15.3 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EME30644.1 - 0.016 14.1 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EME30644.1 - 0.019 15.4 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME30644.1 - 0.053 13.5 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.1 EME30644.1 - 0.14 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase zf-CCHC PF00098.18 EME30645.1 - 9e-16 56.9 19.3 6.2e-06 25.8 0.3 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 EME30645.1 - 1e-08 34.6 9.7 0.015 14.9 0.0 3.4 3 0 0 3 3 3 3 Zinc knuckle GIY-YIG PF01541.19 EME30645.1 - 1.9e-07 31.3 0.3 1.9e-07 31.3 0.2 2.1 3 1 0 3 3 2 1 GIY-YIG catalytic domain zf-CCHC_5 PF14787.1 EME30645.1 - 4.7e-06 25.9 15.2 0.0066 15.9 1.1 3.3 3 0 0 3 3 3 2 GAG-polyprotein viral zinc-finger Toprim_C_rpt PF13368.1 EME30645.1 - 0.0016 18.8 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 2 Topoisomerase C-terminal repeat Zn_dep_PLPC PF00882.13 EME30645.1 - 0.0018 17.9 1.4 0.1 12.2 0.0 2.3 1 1 1 2 2 2 1 Zinc dependent phospholipase C zf-CCHC_2 PF13696.1 EME30645.1 - 0.0023 17.3 17.6 0.7 9.4 0.4 3.3 3 0 0 3 3 3 3 Zinc knuckle T5orf172 PF10544.4 EME30645.1 - 0.003 17.9 0.1 0.0051 17.1 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain zf-CCHC_3 PF13917.1 EME30645.1 - 0.013 15.1 17.0 0.81 9.4 0.3 3.6 3 0 0 3 3 3 0 Zinc knuckle Imm-NTF2 PF15655.1 EME30645.1 - 0.037 14.4 0.1 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 NTF2 fold immunity protein zf-RanBP PF00641.13 EME30645.1 - 0.13 11.3 7.3 2.7 7.1 0.1 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others BRCA-2_OB1 PF09103.5 EME30646.1 - 3.2e-21 75.2 0.0 6.6e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EME30646.1 - 0.00034 20.2 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 BRCA2, helical TPR_MLP1_2 PF07926.7 EME30647.1 - 0.0013 18.4 27.3 0.0013 18.4 18.9 11.9 3 1 8 11 11 11 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EME30647.1 - 0.0034 17.2 25.2 0.0034 17.2 17.5 11.3 5 2 6 12 12 12 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EME30647.1 - 0.0048 16.7 28.2 0.0048 16.7 19.6 9.6 4 2 3 8 8 8 1 Tropomyosin like PALP PF00291.20 EME30648.1 - 1.1e-60 205.4 0.0 2e-60 204.6 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EME30648.1 - 1.3e-12 47.2 0.0 1.4e-07 31.1 0.0 2.7 1 1 1 2 2 2 2 CBS domain PBP-Tp47_a PF14889.1 EME30648.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a AAA_30 PF13604.1 EME30648.1 - 0.15 11.5 0.0 21 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PAP_fibrillin PF04755.7 EME30649.1 - 1.1e-28 100.3 0.0 2.1e-28 99.3 0.0 1.5 1 1 0 1 1 1 1 PAP_fibrillin DEAD PF00270.24 EME30650.1 - 7e-46 155.8 0.5 2.6e-45 153.9 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME30650.1 - 8.2e-25 86.4 0.1 1.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME30650.1 - 4.4e-06 26.6 4.1 1.8e-05 24.6 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME30650.1 - 0.064 13.4 0.5 0.31 11.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain F-box-like PF12937.2 EME30651.1 - 8.6e-13 47.7 0.6 2.1e-12 46.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME30651.1 - 4.3e-11 42.1 1.1 4.3e-11 42.1 0.7 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME30652.1 - 1.4e-12 47.1 1.3 2.3e-12 46.4 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME30652.1 - 4.7e-11 42.0 1.1 4.7e-11 42.0 0.7 2.3 2 0 0 2 2 2 1 F-box domain F-box PF00646.28 EME30653.1 - 2.5e-09 36.5 3.0 2.7e-08 33.2 1.1 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME30653.1 - 6.4e-06 25.7 1.2 1.5e-05 24.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EME30653.1 - 0.0072 16.0 6.4 3.5 7.4 0.3 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EME30653.1 - 0.038 14.0 8.9 28 5.2 1.8 5.7 2 2 1 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EME30653.1 - 0.11 12.7 6.2 7.5 7.2 0.1 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EME30653.1 - 0.32 11.1 9.5 70 3.9 0.0 5.9 5 1 0 5 5 5 0 Leucine Rich repeat Tubulin PF00091.20 EME30654.1 - 5.1e-36 124.5 2.9 9e-35 120.4 2.0 2.3 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.3 EME30654.1 - 2.3e-35 120.5 0.6 8e-35 118.7 0.4 2.0 1 0 0 1 1 1 1 FtsZ family, C-terminal domain CobU PF02283.11 EME30654.1 - 0.098 12.0 1.4 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AA_permease PF00324.16 EME30655.1 - 9.9e-28 96.6 64.6 3.2e-27 95.0 44.8 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME30655.1 - 5.3e-26 91.1 68.8 6.7e-26 90.7 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1404 PF07185.6 EME30657.1 - 0.079 12.5 0.7 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1404) Macoilin PF09726.4 EME30657.1 - 0.49 8.6 10.3 0.62 8.2 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein AIRS PF00586.19 EME30658.1 - 4.9e-15 55.5 0.3 7e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.17 EME30659.1 - 2.3e-16 60.1 0.0 2.8e-15 56.6 0.0 2.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME30659.1 - 1.2e-14 54.2 0.3 2.1e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TPT PF03151.11 EME30660.1 - 1.6e-18 66.7 6.9 1.6e-18 66.7 4.8 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME30660.1 - 6e-05 23.0 30.6 0.00047 20.1 5.9 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EME30660.1 - 0.0065 15.4 21.6 0.029 13.3 15.0 1.9 1 1 0 1 1 1 1 UAA transporter family DUF1637 PF07847.7 EME30663.1 - 4.7e-38 130.5 0.1 5.6e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Diphthamide_syn PF01866.12 EME30665.1 - 6.9e-48 163.4 0.1 9.7e-47 159.6 0.1 2.0 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Tricorn_C1 PF14684.1 EME30666.1 - 0.055 13.3 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF2077 PF09850.4 EME30670.1 - 0.21 10.9 0.1 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) SbcCD_C PF13558.1 EME30671.1 - 5.2e-08 32.7 0.1 1.1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EME30671.1 - 1.8e-05 25.1 18.5 0.81 9.9 12.8 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EME30671.1 - 6e-05 22.3 0.0 0.0016 17.6 0.0 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 EME30671.1 - 0.00083 19.6 6.1 0.009 16.3 0.0 4.0 2 1 1 3 3 3 1 ABC transporter NPV_P10 PF05531.7 EME30671.1 - 0.035 14.3 0.7 1.5 9.1 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CemA PF03040.9 EME30671.1 - 1.5 8.3 9.2 3.3 7.2 1.1 3.2 3 1 0 3 3 3 0 CemA family FMN_red PF03358.10 EME30673.1 - 2.4e-23 82.3 0.0 3.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Aldedh PF00171.17 EME30674.1 - 8.7e-63 212.2 0.0 1.2e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF31 PF01732.11 EME30674.1 - 0.097 11.9 0.1 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Sugar_tr PF00083.19 EME30676.1 - 3.6e-09 35.7 5.8 5.2e-09 35.2 4.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME30676.1 - 5.3e-07 28.6 5.5 5.8e-07 28.5 3.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME30676.1 - 2.8e-06 26.0 1.1 3e-06 25.9 0.7 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein DctQ PF04290.7 EME30676.1 - 0.3 10.8 3.8 3.9 7.2 0.6 2.2 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3792 PF12670.2 EME30676.1 - 2.2 8.1 8.1 0.061 13.1 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Gly_transf_sug PF04488.10 EME30677.1 - 0.0023 18.2 0.2 0.0051 17.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3524 PF12038.3 EME30677.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) Kinesin PF00225.18 EME30678.1 - 1.5e-88 296.7 3.3 3.6e-88 295.4 2.3 1.7 1 0 0 1 1 1 1 Kinesin motor domain Perm-CXXC PF15629.1 EME30679.1 - 0.029 14.3 1.5 0.083 12.9 1.1 1.7 1 0 0 1 1 1 0 Permuted single zf-CXXC unit DUF1180 PF06679.7 EME30679.1 - 0.086 12.7 3.7 0.16 11.8 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Prenyltrans PF00432.16 EME30680.1 - 1.3e-40 136.6 16.8 5e-09 35.5 0.5 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EME30680.1 - 1.1e-24 86.9 0.0 3e-17 63.0 0.0 4.0 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME30680.1 - 1.1e-07 31.8 0.0 0.022 14.7 0.0 3.4 3 1 1 4 4 4 2 Prenyltransferase-like FYVE PF01363.16 EME30682.1 - 0.052 13.4 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Glyco_transf_8 PF01501.15 EME30683.1 - 7.4e-13 48.4 0.6 1.4e-12 47.5 0.4 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 SecE PF00584.15 EME30684.1 - 1.5e-12 46.8 0.0 1.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TAT_signal PF10518.4 EME30684.1 - 0.0061 16.4 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 EME30684.1 - 0.071 12.3 0.2 0.12 11.5 0.1 1.4 1 1 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TFIID_20kDa PF03847.8 EME30686.1 - 8.2e-19 67.6 0.8 1.3e-18 66.9 0.2 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EME30686.1 - 1e-06 28.7 0.1 1.7e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME30686.1 - 2.1e-05 24.4 0.2 3.5e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EME30686.1 - 0.041 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3609 PF12259.3 EME30686.1 - 0.1 11.2 0.2 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) tRNA_bind PF01588.15 EME30688.1 - 9e-34 115.1 0.2 1.9e-33 114.1 0.1 1.6 2 0 0 2 2 2 1 Putative tRNA binding domain tRNA_bind PF01588.15 EME30689.1 - 8e-34 115.3 0.2 1.7e-33 114.3 0.1 1.5 2 0 0 2 2 2 1 Putative tRNA binding domain RWP-RK PF02042.10 EME30690.1 - 1.2e-18 66.6 0.0 3.2e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 RWP-RK domain Exonuc_VII_L PF02601.10 EME30690.1 - 0.073 12.2 2.6 0.14 11.2 1.8 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Syntaxin PF00804.20 EME30690.1 - 0.15 12.2 8.1 0.22 11.6 1.2 2.4 2 0 0 2 2 2 0 Syntaxin Cluap1 PF10234.4 EME30690.1 - 0.92 8.6 5.9 0.21 10.7 0.6 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Cep57_MT_bd PF06657.8 EME30690.1 - 1.3 9.0 8.1 3.9 7.4 0.7 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SET PF00856.23 EME30691.1 - 1.2e-06 28.8 0.0 7.9e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Ribosomal_L29e PF01779.12 EME30692.1 - 4.7e-20 71.1 8.0 4.7e-20 71.1 5.6 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family NIF PF03031.13 EME30693.1 - 1.6e-46 157.8 0.3 2.9e-46 157.0 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EME30693.1 - 0.014 15.5 0.2 0.2 11.8 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase TIP120 PF08623.5 EME30694.1 - 3.4e-28 98.3 0.1 3.4e-28 98.3 0.1 5.0 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EME30694.1 - 2.8e-17 62.7 15.4 0.014 15.6 0.9 9.3 9 2 1 10 10 10 5 HEAT repeats HEAT PF02985.17 EME30694.1 - 1e-09 37.6 33.4 0.079 13.0 0.1 12.5 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.1 EME30694.1 - 1.8e-08 34.5 22.1 0.063 13.7 0.0 10.8 9 3 2 11 11 11 3 HEAT-like repeat CLASP_N PF12348.3 EME30694.1 - 5.2e-07 29.2 15.0 0.003 16.9 0.0 6.8 6 1 2 8 8 8 2 CLASP N terminal Ipi1_N PF12333.3 EME30694.1 - 0.093 12.7 12.4 2.4 8.1 0.6 5.5 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EME30694.1 - 1.9 8.4 11.1 99 2.9 0.1 6.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EME30695.1 - 2.4e-18 66.2 0.0 2.4e-18 66.2 0.0 5.1 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EME30695.1 - 1.5e-17 63.6 14.1 0.013 15.7 0.9 9.0 9 2 1 10 10 10 5 HEAT repeats HEAT PF02985.17 EME30695.1 - 6.9e-10 38.1 33.4 0.076 13.1 0.1 12.6 14 0 0 14 14 14 3 HEAT repeat HEAT_EZ PF13513.1 EME30695.1 - 8.7e-07 29.2 22.8 0.061 13.8 0.0 10.3 9 3 3 12 12 12 3 HEAT-like repeat CLASP_N PF12348.3 EME30695.1 - 1.8e-06 27.4 16.5 0.0029 16.9 0.0 6.6 5 1 2 7 7 7 2 CLASP N terminal Ipi1_N PF12333.3 EME30695.1 - 0.077 12.9 12.3 2.3 8.2 0.6 5.5 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EME30695.1 - 1.7 8.6 11.1 96 3.0 0.1 6.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EME30695.1 - 3.6 7.4 9.8 2.5 7.9 0.2 4.2 5 0 0 5 5 5 0 Parkin co-regulated protein AAA PF00004.24 EME30696.1 - 1.2e-13 51.4 0.1 2.6e-13 50.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME30696.1 - 3.5e-05 23.9 3.7 0.016 15.3 0.6 3.1 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EME30696.1 - 7.4e-05 21.9 1.6 0.0022 17.1 0.1 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME30696.1 - 0.00015 21.4 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME30696.1 - 0.0018 18.1 1.2 0.026 14.4 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EME30696.1 - 0.0026 17.4 0.1 0.0074 16.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EME30696.1 - 0.0032 17.1 0.2 0.008 15.8 0.2 1.7 1 0 0 1 1 1 1 NTPase AAA_17 PF13207.1 EME30696.1 - 0.0038 18.0 5.4 0.0039 17.9 0.8 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME30696.1 - 0.011 15.9 0.1 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 EME30696.1 - 0.011 15.6 1.0 0.021 14.6 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EME30696.1 - 0.014 14.3 0.3 0.068 12.1 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EME30696.1 - 0.017 13.7 0.1 0.032 12.8 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EME30696.1 - 0.023 14.9 4.6 0.061 13.6 0.2 2.9 3 1 0 3 3 3 0 AAA domain KTI12 PF08433.5 EME30696.1 - 0.026 13.7 0.0 0.026 13.7 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EME30696.1 - 0.026 13.9 0.1 1.7 8.0 0.1 2.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) RuvB_N PF05496.7 EME30696.1 - 0.027 13.5 0.2 0.21 10.6 0.2 2.4 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME30696.1 - 0.029 13.9 0.8 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EME30696.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EME30696.1 - 0.042 13.8 0.6 0.25 11.3 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.12 EME30696.1 - 0.051 12.9 0.1 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EME30696.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PVL_ORF50 PF07768.6 EME30696.1 - 0.083 12.8 5.6 0.23 11.4 3.9 1.7 1 0 0 1 1 1 0 PVL ORF-50-like family AAA_28 PF13521.1 EME30696.1 - 0.12 12.2 3.4 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EME30696.1 - 0.17 10.6 0.1 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_2 PF07724.9 EME30696.1 - 0.18 11.6 2.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF3987 PF13148.1 EME30696.1 - 2 6.8 7.6 2.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DNA_pol_A_exo1 PF01612.15 EME30697.1 - 3.5e-41 140.5 0.3 3.5e-41 140.5 0.2 1.8 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.18 EME30697.1 - 2.3e-11 43.2 0.0 6.6e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 EME30697.1 - 1.4e-05 25.2 1.3 0.00034 20.8 0.1 3.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain RICH PF05062.7 EME30697.1 - 0.012 15.7 2.7 0.012 15.7 1.9 3.5 3 0 0 3 3 3 0 RICH domain CI-B14_5a PF07347.7 EME30698.1 - 0.00027 20.6 0.2 0.00036 20.2 0.2 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Myb_DNA-binding PF00249.26 EME30699.1 - 3.5e-06 26.9 0.2 1.3e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME30699.1 - 4.3 7.5 9.3 0.42 10.7 0.6 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain V-SNARE_C PF12352.3 EME30700.1 - 1.5e-05 24.9 6.1 2.2e-05 24.4 0.3 3.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.14 EME30700.1 - 6.7e-05 22.5 3.5 6.7e-05 22.5 2.4 3.0 3 0 0 3 3 3 2 SNARE domain NPV_P10 PF05531.7 EME30700.1 - 0.022 14.9 1.2 0.18 12.0 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_M28 PF04389.12 EME30701.1 - 1.2e-29 103.3 0.0 1.9e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME30701.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 PA domain Peptidase_M28 PF04389.12 EME30702.1 - 1.2e-29 103.2 0.0 2e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME30702.1 - 0.032 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 PA domain RrnaAD PF00398.15 EME30703.1 - 2.2e-47 161.3 0.0 2.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EME30703.1 - 4.6e-05 23.4 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME30703.1 - 0.00034 20.3 0.0 0.00056 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME30703.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EME30703.1 - 0.017 14.3 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_18 PF12847.2 EME30703.1 - 0.029 14.9 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EME30703.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain ABC_tran PF00005.22 EME30704.1 - 4.8e-53 179.1 12.8 3.3e-26 92.2 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 EME30704.1 - 4.4e-22 77.7 4.2 7.8e-21 73.7 0.4 4.1 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EME30704.1 - 8.2e-21 75.2 13.2 4.1e-05 23.6 0.0 4.8 3 2 2 5 5 5 4 AAA domain AAA_29 PF13555.1 EME30704.1 - 2e-09 36.8 0.4 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EME30704.1 - 3.4e-08 33.5 5.0 0.0087 15.8 0.0 3.8 3 1 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 EME30704.1 - 8.8e-08 32.3 5.1 0.0025 17.9 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EME30704.1 - 2.5e-06 27.2 2.7 0.026 14.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EME30704.1 - 7.4e-06 26.0 1.5 0.043 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.7 EME30704.1 - 1.1e-05 25.1 0.0 0.2 11.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 EME30704.1 - 1.2e-05 24.7 16.1 0.0057 15.9 0.3 5.0 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EME30704.1 - 1.2e-05 24.0 16.6 0.14 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EME30704.1 - 1.9e-05 25.4 1.2 0.096 13.5 0.0 3.5 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EME30704.1 - 5.5e-05 22.4 0.1 0.041 13.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EME30704.1 - 9.4e-05 22.8 10.4 0.024 15.1 0.0 4.0 4 1 0 4 4 2 2 Miro-like protein AAA_33 PF13671.1 EME30704.1 - 0.0001 22.1 0.7 0.029 14.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EME30704.1 - 0.00014 21.4 0.1 0.12 11.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EME30704.1 - 0.00032 20.1 0.3 0.89 8.9 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EME30704.1 - 0.00075 19.2 0.1 0.51 10.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EME30704.1 - 0.0012 19.1 8.9 0.12 12.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 EME30704.1 - 0.0013 18.4 0.2 4 7.2 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_25 PF13481.1 EME30704.1 - 0.0015 17.9 0.0 0.69 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EME30704.1 - 0.0015 18.4 3.6 0.028 14.3 0.1 3.5 3 1 0 3 3 2 1 50S ribosome-binding GTPase MobB PF03205.9 EME30704.1 - 0.0016 18.1 8.6 0.086 12.5 0.0 3.2 3 1 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EME30704.1 - 0.0023 16.8 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_14 PF13173.1 EME30704.1 - 0.0028 17.5 0.5 0.41 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EME30704.1 - 0.0031 17.0 0.1 2.5 7.5 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EME30704.1 - 0.0033 16.6 0.1 7.2 5.7 0.0 3.6 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.7 EME30704.1 - 0.0043 16.3 0.2 3.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_23 PF13476.1 EME30704.1 - 0.006 16.9 0.0 0.006 16.9 0.0 5.2 5 1 1 6 6 5 2 AAA domain ChaC PF04752.7 EME30704.1 - 0.0076 16.2 0.1 0.024 14.5 0.1 1.9 1 0 0 1 1 1 1 ChaC-like protein SbcCD_C PF13558.1 EME30704.1 - 0.0093 15.8 0.1 5 7.1 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Sigma54_activ_2 PF14532.1 EME30704.1 - 0.013 15.5 0.0 0.66 10.0 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EME30704.1 - 0.013 15.6 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 EME30704.1 - 0.017 14.6 10.3 0.023 14.1 0.0 3.8 4 0 0 4 4 4 0 AAA-like domain AAA_24 PF13479.1 EME30704.1 - 0.02 14.4 2.7 9.1 5.7 0.0 4.1 3 1 1 4 4 4 0 AAA domain PduV-EutP PF10662.4 EME30704.1 - 0.042 13.3 0.3 6.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EME30704.1 - 0.05 13.1 0.0 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TMEM219 PF14940.1 EME30704.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane 219 AAA PF00004.24 EME30704.1 - 0.19 11.9 8.0 3.2 7.9 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) BMP2K_C PF15282.1 EME30704.1 - 0.19 11.8 7.8 0.38 10.8 5.4 1.4 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus ArgK PF03308.11 EME30704.1 - 0.52 9.0 7.4 3.9 6.1 0.1 3.3 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 EME30704.1 - 0.53 10.0 19.1 1.9 8.2 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function DUF87 Rtf2 PF04641.7 EME30704.1 - 0.74 8.9 18.8 1.3 8.1 13.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SRP54 PF00448.17 EME30704.1 - 0.98 8.8 6.1 4.1 6.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF1510 PF07423.6 EME30704.1 - 1.4 8.2 20.8 2.6 7.3 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AAA_28 PF13521.1 EME30704.1 - 4.1 7.3 12.1 1.4 8.9 0.0 3.7 4 1 0 4 4 3 0 AAA domain HSP70 PF00012.15 EME30704.1 - 4.7 5.0 17.7 10 3.8 12.3 1.5 1 0 0 1 1 1 0 Hsp70 protein DEAD PF00270.24 EME30705.1 - 4.7e-18 65.2 0.0 9.8e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 EME30705.1 - 2e-08 33.8 0.0 5.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 EME30705.1 - 3.4e-07 30.0 0.0 3.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPC22 PF04573.7 EME30706.1 - 3.2e-24 85.1 0.4 3.7e-24 84.8 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF4477 PF14780.1 EME30707.1 - 1.1e-05 24.9 11.8 0.0017 17.8 0.9 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) Methyltransf_23 PF13489.1 EME30710.1 - 6.7e-18 64.9 0.0 8.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME30710.1 - 9.7e-17 60.9 0.0 1.6e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30710.1 - 1.6e-16 60.5 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME30710.1 - 2.4e-13 50.6 0.0 4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30710.1 - 7.4e-12 45.6 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME30710.1 - 1.6e-09 37.2 0.0 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EME30710.1 - 5.8e-08 33.0 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME30710.1 - 4.3e-06 26.0 0.0 6.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EME30710.1 - 0.00044 19.0 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.7 EME30710.1 - 0.00047 19.1 0.0 0.00074 18.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 EME30710.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EME30710.1 - 0.0043 16.4 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EME30710.1 - 0.0056 15.8 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME30710.1 - 0.019 15.0 0.0 0.059 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FF PF01846.14 EME30711.1 - 0.00083 19.2 0.1 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 FF domain AMP-binding PF00501.23 EME30712.1 - 1.9e-91 306.5 0.0 2.2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME30712.1 - 2.4e-17 63.6 0.4 5.4e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 EME30712.1 - 0.11 12.2 0.1 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Arf PF00025.16 EME30714.1 - 9.9e-64 213.7 0.0 1.1e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME30714.1 - 1.8e-10 40.3 0.0 2.2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME30714.1 - 1.5e-09 37.4 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME30714.1 - 8e-09 34.6 0.0 8.1e-06 24.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EME30714.1 - 9.6e-08 31.9 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME30714.1 - 1.9e-07 31.5 0.0 2.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME30714.1 - 3.8e-07 29.5 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME30714.1 - 0.0032 16.9 0.2 0.15 11.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EME30714.1 - 0.004 16.6 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EME30714.1 - 0.032 13.6 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 EME30715.1 - 3.7e-50 169.5 0.0 4.1e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EME30715.1 - 3.2e-06 26.0 0.0 5.1e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EME30715.1 - 4.2e-06 26.2 0.0 4.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME30715.1 - 0.00018 22.0 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EME30715.1 - 0.0015 17.7 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME30715.1 - 0.0052 15.9 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME30715.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME30715.1 - 0.092 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain EF1_GNE PF00736.14 EME30716.1 - 1.7e-31 107.7 1.3 3.5e-31 106.7 0.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.1 EME30716.1 - 0.00027 21.3 0.0 0.00079 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME30716.1 - 0.0042 16.9 3.7 0.014 15.2 0.0 2.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME30716.1 - 0.0053 16.7 0.9 0.33 10.9 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EF-1_beta_acid PF10587.4 EME30716.1 - 0.035 14.2 14.8 0.037 14.1 8.4 2.4 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF349 PF03993.7 EME30716.1 - 0.036 14.2 0.4 0.036 14.2 0.2 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) TP53IP5 PF15331.1 EME30716.1 - 0.38 10.6 2.4 0.52 10.2 1.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_2 PF13639.1 EME30717.1 - 2e-13 49.9 5.6 3.1e-13 49.2 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME30717.1 - 1.6e-09 37.2 3.2 2.6e-09 36.5 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME30717.1 - 5.2e-09 35.9 5.2 8.4e-09 35.3 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME30717.1 - 1.9e-08 34.3 1.8 3.3e-08 33.5 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EME30717.1 - 5.6e-08 32.3 2.9 8.7e-08 31.7 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME30717.1 - 3e-07 29.9 3.3 4.6e-07 29.4 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME30717.1 - 0.0094 15.7 1.7 0.018 14.8 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EME30717.1 - 0.086 12.8 5.8 0.36 10.8 4.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EME30717.1 - 0.11 12.0 2.1 0.26 10.8 1.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EME30717.1 - 0.11 12.4 3.7 0.18 11.8 2.5 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EME30717.1 - 0.13 11.8 4.3 0.24 11.0 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EME30717.1 - 0.3 11.1 2.8 0.68 10.0 1.9 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EME30717.1 - 0.76 9.5 2.9 0.7 9.6 0.3 2.2 2 1 1 3 3 3 0 RING-type zinc-finger DUF3624 PF12292.3 EME30717.1 - 6.2 7.2 9.0 2.7 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Gtr1_RagA PF04670.7 EME30718.1 - 5.9e-89 297.1 0.2 7.8e-89 296.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EME30718.1 - 5.1e-07 29.2 0.0 9.5e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EME30718.1 - 3.7e-06 26.3 0.0 6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME30718.1 - 0.00019 21.8 0.0 0.00048 20.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME30718.1 - 0.00047 20.0 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EME30718.1 - 0.00091 19.5 0.0 0.0048 17.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EME30718.1 - 0.035 13.0 0.0 0.082 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EME30718.1 - 0.057 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EME30718.1 - 0.067 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EME30718.1 - 0.12 11.2 0.2 0.95 8.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EME30718.1 - 0.12 11.7 0.2 4 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME30718.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EME30719.1 - 6e-89 297.1 0.2 8.3e-89 296.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EME30719.1 - 5.4e-07 29.1 0.0 9.9e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EME30719.1 - 3.8e-06 26.2 0.0 6.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME30719.1 - 0.0002 21.8 0.0 0.0005 20.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME30719.1 - 0.00049 20.0 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EME30719.1 - 0.00096 19.4 0.0 0.005 17.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EME30719.1 - 0.036 12.9 0.0 0.085 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EME30719.1 - 0.057 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EME30719.1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EME30719.1 - 0.12 11.2 0.2 0.98 8.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EME30719.1 - 0.13 11.7 0.2 4.1 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME30719.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain V_ATPase_I PF01496.14 EME30720.1 - 1.5e-234 780.3 5.1 1.7e-234 780.1 3.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cas_Csa4 PF09703.5 EME30720.1 - 0.037 13.0 0.3 0.06 12.3 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) V-SNARE PF05008.10 EME30720.1 - 0.078 13.1 1.1 1.4 9.1 0.2 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Uds1 PF15456.1 EME30720.1 - 1.5 8.8 8.4 0.3 11.0 1.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation tRNA-synt_1g PF09334.6 EME30721.1 - 8.8e-144 478.9 0.1 1.2e-143 478.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.15 EME30721.1 - 8.3e-25 86.4 0.2 1.6e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.17 EME30721.1 - 8.4e-07 27.3 0.2 0.013 13.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 EME30721.1 - 0.034 13.9 8.1 0.29 10.9 2.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 EME30721.1 - 0.41 10.7 6.0 0.67 10.1 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 EME30721.1 - 0.45 9.7 7.0 12 5.3 0.0 3.0 2 1 1 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EME30721.1 - 0.87 9.3 5.8 4.3 7.1 0.3 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.1 EME30721.1 - 4 7.1 6.3 1.6 8.4 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1g PF09334.6 EME30722.1 - 8.9e-144 478.9 0.1 1.2e-143 478.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.15 EME30722.1 - 8.3e-25 86.4 0.2 1.6e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.17 EME30722.1 - 8.5e-07 27.3 0.2 0.013 13.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 EME30722.1 - 0.033 14.0 8.0 0.27 11.1 2.8 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 EME30722.1 - 0.4 10.8 6.0 0.66 10.1 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 EME30722.1 - 0.46 9.7 7.0 12 5.3 0.0 3.0 2 1 1 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EME30722.1 - 0.88 9.3 5.8 4.3 7.1 0.3 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.1 EME30722.1 - 4.1 7.1 6.3 1.6 8.4 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DAD PF02109.11 EME30723.1 - 3.7e-40 136.5 2.4 4.2e-40 136.3 1.6 1.0 1 0 0 1 1 1 1 DAD family ABC2_membrane_3 PF12698.2 EME30723.1 - 0.15 11.0 3.4 0.17 10.8 2.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein p450 PF00067.17 EME30724.1 - 3.3e-37 128.0 0.0 7.9e-27 93.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Surp PF01805.15 EME30725.1 - 0.0014 18.2 0.1 0.0059 16.2 0.0 1.8 2 0 0 2 2 2 1 Surp module Ribosomal_L7Ae PF01248.21 EME30726.1 - 3.9e-20 71.1 0.1 6.8e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.21 EME30727.1 - 3.9e-20 71.1 0.1 6.8e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TauE PF01925.14 EME30728.1 - 2e-22 79.8 26.3 1.8e-13 50.4 0.3 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE EcoRI_methylase PF13651.1 EME30728.1 - 0.0099 14.9 0.4 0.016 14.3 0.3 1.2 1 0 0 1 1 1 1 Adenine-specific methyltransferase EcoRI DUF106 PF01956.11 EME30729.1 - 0.038 13.5 0.6 0.042 13.3 0.4 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FGGY_C PF02782.11 EME30730.1 - 3.4e-40 137.7 0.1 1.3e-39 135.9 0.1 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME30730.1 - 4.8e-27 94.8 0.2 1.5e-26 93.1 0.2 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 EME30730.1 - 0.0025 17.2 0.0 0.0068 15.7 0.0 1.7 1 0 0 1 1 1 1 Hexokinase BcrAD_BadFG PF01869.15 EME30730.1 - 0.0066 15.7 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Aa_trans PF01490.13 EME30732.1 - 1e-36 126.3 31.4 1.2e-36 126.0 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyoxalase_2 PF12681.2 EME30733.1 - 1.3e-06 29.0 0.0 1.5e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME30733.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME30733.1 - 3.8e-05 23.6 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aldo_ket_red PF00248.16 EME30734.1 - 8.6e-57 192.1 0.0 9.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Med28 PF11594.3 EME30734.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 28 Amidase PF01425.16 EME30734.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amidase Coprogen_oxidas PF01218.13 EME30735.1 - 2.3e-134 446.5 0.1 2.8e-134 446.2 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CAF1 PF04857.15 EME30736.1 - 3.1e-67 226.6 0.0 4.3e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease PTH2 PF01981.11 EME30737.1 - 2.6e-08 33.5 0.1 4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ACBP PF00887.14 EME30738.1 - 8.5e-30 102.2 3.2 1e-29 102.0 2.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein RNB PF00773.14 EME30739.1 - 1.2e-74 251.5 0.0 3.8e-74 249.9 0.0 1.9 1 1 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EME30739.1 - 9.3e-05 21.8 0.1 0.00028 20.3 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain UBA PF00627.26 EME30739.1 - 0.0003 20.5 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Heme_oxygenase PF01126.15 EME30740.1 - 2.7e-10 40.1 0.0 5.3e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Heme oxygenase UQ_con PF00179.21 EME30741.1 - 4.6e-37 126.5 0.1 7e-37 125.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_60s PF00428.14 EME30741.1 - 0.074 13.4 4.7 0.11 12.8 3.2 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.9 EME30741.1 - 0.2 9.6 3.7 0.22 9.5 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EME30741.1 - 2.4 8.1 5.6 1.4 8.8 2.6 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 CobT PF06213.7 EME30741.1 - 4.9 6.1 11.9 6.6 5.7 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPL4 PF05021.10 EME30742.1 - 1.6e-46 158.8 0.0 2.4e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 EME30742.1 - 4.1e-07 30.1 0.0 1.2e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 JAB PF01398.16 EME30742.1 - 2.6e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-NPL4 PF05020.10 EME30742.1 - 0.0039 16.8 0.1 0.0083 15.7 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Rad60-SLD PF11976.3 EME30742.1 - 0.1 12.3 0.1 0.27 10.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MRP-L46 PF11788.3 EME30743.1 - 0.011 16.3 0.8 0.028 15.0 0.4 1.9 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 PseudoU_synth_1 PF01416.15 EME30744.1 - 5.2e-25 87.9 2.5 3.4e-15 56.3 0.0 4.0 3 1 0 3 3 3 2 tRNA pseudouridine synthase GTP_EFTU PF00009.22 EME30745.1 - 1.3e-52 177.9 0.0 2.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME30745.1 - 1.9e-36 124.2 0.1 5.4e-36 122.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME30745.1 - 3.2e-16 59.2 0.6 9.3e-16 57.7 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EME30745.1 - 0.00016 21.2 0.3 0.00016 21.2 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EME30745.1 - 0.00017 21.5 0.1 0.00046 20.1 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EME30745.1 - 0.14 10.7 0.0 0.65 8.6 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit SpoU_methylase PF00588.14 EME30747.1 - 1.1e-25 90.1 0.3 1.4e-24 86.5 0.2 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EME30747.1 - 1.6e-13 50.5 0.0 3.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding TFIIIC_sub6 PF10419.4 EME30748.1 - 1.6e-08 33.8 0.1 2.3e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 TFIIIC subunit B12D PF06522.6 EME30749.1 - 6.9e-13 48.0 0.0 8.1e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Helicase_C_3 PF13625.1 EME30750.1 - 1.8e-25 89.1 0.0 4.1e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME30750.1 - 5.1e-14 52.5 0.0 1.2e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME30750.1 - 5.7e-10 38.9 0.0 2.2e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME30750.1 - 3.2e-08 32.7 0.1 4.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EME30750.1 - 0.0063 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF155 PF02582.9 EME30751.1 - 1.1e-36 126.4 0.1 1.9e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AFG1_ATPase PF03969.11 EME30753.1 - 2e-91 306.4 0.1 2.6e-91 306.1 0.1 1.1 1 0 0 1 1 1 1 AFG1-like ATPase Arch_ATPase PF01637.13 EME30753.1 - 0.016 14.9 0.2 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EME30753.1 - 0.031 14.2 1.2 2.2 8.2 0.0 2.9 2 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EME30753.1 - 0.033 14.3 0.1 0.25 11.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain UPF0697 PF15117.1 EME30754.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 7tm_2 PF00002.19 EME30755.1 - 2.7e-17 62.6 12.2 6.6e-17 61.3 8.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EME30755.1 - 1.6e-12 46.9 16.8 1.6e-12 46.9 11.6 1.9 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 EME30755.1 - 4.5e-05 22.2 8.3 6.3e-05 21.7 5.8 1.2 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_1 PF00001.16 EME30755.1 - 5.6e-05 22.3 10.0 5.6e-05 22.3 6.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EME30755.1 - 9.4 5.7 17.6 0.04 13.4 4.4 2.5 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 Mito_carr PF00153.22 EME30757.1 - 2.3e-67 222.7 0.1 2.7e-24 84.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ETC_C1_NDUFA4 PF04800.7 EME30758.1 - 1.1e-24 86.2 0.1 1.6e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 EME30758.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) CKS PF01111.14 EME30759.1 - 1.4e-38 130.5 0.3 1.8e-38 130.2 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF718 PF05336.8 EME30759.1 - 0.13 12.0 0.0 5.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF718) PCI PF01399.22 EME30760.1 - 1.2e-07 32.0 0.5 1.2e-07 32.0 0.3 3.8 4 0 0 4 4 4 1 PCI domain HTH_20 PF12840.2 EME30760.1 - 0.094 12.5 3.6 12 5.8 0.0 4.0 3 0 0 3 3 3 0 Helix-turn-helix domain COX16 PF14138.1 EME30761.1 - 5.2e-15 55.3 0.2 6.2e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Mitovir_RNA_pol PF05919.6 EME30761.1 - 0.044 12.7 0.1 0.053 12.4 0.1 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase SASP PF00269.15 EME30761.1 - 0.071 12.9 0.5 0.11 12.3 0.3 1.4 1 1 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type DUF1995 PF09353.5 EME30762.1 - 3.3e-39 134.6 0.0 7.7e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) ubiquitin PF00240.18 EME30762.1 - 1.8e-19 68.9 0.1 3.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME30762.1 - 3.5e-11 42.6 0.1 1.1e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME30762.1 - 7.8e-05 22.8 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EME30762.1 - 0.00075 19.3 0.0 0.0025 17.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EME30762.1 - 0.012 16.1 0.2 0.064 13.8 0.1 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD DUF1995 PF09353.5 EME30763.1 - 3.3e-39 134.7 0.0 7.5e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) ubiquitin PF00240.18 EME30763.1 - 1.7e-19 68.9 0.1 3.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME30763.1 - 3.7e-11 42.5 0.1 1.1e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME30763.1 - 7.7e-05 22.8 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EME30763.1 - 0.00073 19.3 0.0 0.0025 17.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EME30763.1 - 0.012 16.1 0.2 0.063 13.8 0.1 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD WD40 PF00400.27 EME30764.1 - 8.2e-08 31.8 1.8 5.9e-07 29.1 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.5 EME30764.1 - 1e-05 23.8 0.1 0.018 13.0 0.0 2.4 2 1 0 2 2 2 2 CRT10 Nup160 PF11715.3 EME30764.1 - 0.007 14.5 0.0 0.011 13.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EME30765.1 - 9.3e-08 31.6 1.7 6.4e-07 29.0 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.5 EME30765.1 - 1e-06 27.0 0.1 0.022 12.7 0.0 2.5 2 1 0 2 2 2 2 CRT10 Nup160 PF11715.3 EME30765.1 - 0.0067 14.6 0.0 0.013 13.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF3608 PF12257.3 EME30766.1 - 3.6e-35 121.2 1.8 5.8e-24 84.4 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) DUF3608 PF12257.3 EME30767.1 - 3.6e-35 121.2 1.8 5.9e-24 84.4 1.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) Aa_trans PF01490.13 EME30768.1 - 1.1e-34 119.6 38.5 1.3e-34 119.4 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME30768.1 - 1.7e-06 27.1 19.1 1.7e-06 27.1 13.2 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EME30768.1 - 0.0066 15.1 24.9 0.021 13.5 17.1 1.9 1 1 0 1 1 1 1 Spore germination protein DUF3598 PF12204.3 EME30769.1 - 6.8e-07 28.7 0.0 0.00014 21.2 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3598) DUF3598 PF12204.3 EME30770.1 - 6.6e-07 28.8 0.0 0.00014 21.2 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3598) TPMT PF05724.6 EME30771.1 - 9.7e-34 116.7 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EME30771.1 - 2.8e-10 39.9 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME30771.1 - 6e-08 33.0 0.0 8.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME30771.1 - 1.7e-05 25.1 0.0 2.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME30771.1 - 0.0001 22.8 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30771.1 - 0.00057 20.3 0.0 0.0008 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME30771.1 - 0.0052 15.9 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EME30771.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EME30771.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB 60KD_IMP PF02096.15 EME30772.1 - 1.7e-18 67.0 0.1 9.8e-18 64.5 0.1 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein 60KD_IMP PF02096.15 EME30773.1 - 2.9e-23 82.5 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein FtsJ PF01728.14 EME30774.1 - 1.6e-65 220.4 0.0 2.1e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EME30774.1 - 0.007 16.9 0.0 0.39 11.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME30774.1 - 0.025 14.1 0.0 0.46 10.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.16 EME30775.1 - 4.8e-149 495.7 0.0 7.2e-149 495.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EME30775.1 - 2.4e-41 141.1 0.4 4.1e-41 140.4 0.3 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME30775.1 - 0.0014 18.5 0.0 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EME30775.1 - 0.0091 14.7 0.1 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PGI PF00342.14 EME30776.1 - 1.2e-194 647.3 0.0 1.4e-194 647.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Fer2_3 PF13085.1 EME30777.1 - 2e-29 101.6 0.0 3.2e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EME30777.1 - 1.7e-11 44.3 1.9 1.7e-11 44.3 1.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EME30777.1 - 1.7e-09 37.5 1.1 1.7e-09 37.5 0.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EME30777.1 - 1.8e-07 31.4 0.2 1.8e-07 31.4 0.2 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EME30777.1 - 1.2e-05 25.0 2.6 1.2e-05 25.0 1.8 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EME30777.1 - 1.4e-05 25.3 0.7 1.4e-05 25.3 0.5 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EME30777.1 - 0.0005 20.2 7.1 0.02 15.1 3.9 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EME30777.1 - 0.0033 17.1 0.5 0.0033 17.1 0.3 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_2 PF12797.2 EME30777.1 - 0.033 14.1 11.0 0.31 11.0 1.0 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.1 EME30777.1 - 0.035 14.6 4.1 4.2 7.9 0.0 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.1 EME30777.1 - 0.34 11.3 3.9 16 5.9 0.9 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4 PF00037.22 EME30777.1 - 0.42 10.2 12.9 0.55 9.9 1.3 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.2 EME30777.1 - 1 9.8 15.1 0.28 11.6 0.6 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.2 EME30777.1 - 3.4 7.7 13.7 2.8 7.9 0.9 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain FtsZ_C PF12327.3 EME30778.1 - 4.9e-35 119.4 0.5 1.1e-34 118.3 0.4 1.6 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin PF00091.20 EME30778.1 - 2.5e-33 115.7 0.3 6.4e-33 114.3 0.2 1.6 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain ThiF PF00899.16 EME30778.1 - 0.077 12.8 0.9 0.18 11.5 0.6 1.8 1 1 0 1 1 1 0 ThiF family Tubulin_2 PF13809.1 EME30778.1 - 9.7 5.0 8.1 46 2.7 0.1 2.8 1 1 1 2 2 2 0 Tubulin like Citrate_synt PF00285.16 EME30779.1 - 1.2e-125 418.9 0.0 1.8e-125 418.4 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase PRK PF00485.13 EME30780.1 - 9.3e-72 240.6 0.0 1.7e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EME30780.1 - 0.0027 17.9 0.1 0.012 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME30780.1 - 0.0035 18.1 0.0 0.011 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF3378 PF11858.3 EME30780.1 - 0.03 14.3 0.7 0.067 13.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) AAA_16 PF13191.1 EME30780.1 - 0.18 11.7 0.3 5.9 6.8 0.0 2.6 1 1 1 3 3 3 0 AAA ATPase domain RRM_1 PF00076.17 EME30781.1 - 1.1e-23 82.5 0.0 1.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30781.1 - 2.4e-15 56.2 0.0 4.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EME30781.1 - 2.6e-15 56.2 5.3 2.6e-15 56.2 3.7 3.0 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 EME30781.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EME30781.1 - 6.1e-06 25.4 3.5 1.9e-05 23.8 2.4 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 EME30782.1 - 3.9e-22 77.6 0.0 6.4e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EME30782.1 - 2.9e-15 56.1 5.3 2.9e-15 56.1 3.7 3.0 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 EME30782.1 - 2e-14 53.3 0.0 3.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30782.1 - 1.2e-07 31.4 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EME30782.1 - 6.8e-06 25.2 3.5 2.1e-05 23.7 2.4 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DAO PF01266.19 EME30783.1 - 0.089 11.6 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.20 EME30784.1 - 9.7e-35 119.9 0.0 1.6e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30784.1 - 7e-14 51.5 0.0 1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME30784.1 - 0.0048 16.6 0.0 0.041 13.6 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME30784.1 - 0.022 13.7 0.0 0.062 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EME30784.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EME30784.1 - 0.072 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2428 PF10350.4 EME30785.1 - 2.3e-24 85.7 0.7 6e-24 84.4 0.5 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) E1-E2_ATPase PF00122.15 EME30785.1 - 2.1e-21 76.0 0.0 6.5e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EME30785.1 - 5.3e-17 62.9 0.0 3.3e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME30785.1 - 3.5e-12 46.8 0.0 1.2e-11 45.2 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME30785.1 - 4.8e-09 36.0 0.0 1.4e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME30785.1 - 0.00034 20.2 0.1 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HEAT PF02985.17 EME30785.1 - 0.0041 17.0 1.2 0.34 11.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HAD_2 PF13419.1 EME30785.1 - 0.042 14.0 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UQ_con PF00179.21 EME30786.1 - 1e-49 167.5 0.0 1.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME30786.1 - 0.0098 15.6 0.1 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B Radical_SAM PF04055.16 EME30787.1 - 7.7e-12 45.6 0.0 1.5e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DAZAP2 PF11029.3 EME30787.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) PPR_2 PF13041.1 EME30788.1 - 1.5e-64 213.7 5.1 2.2e-11 43.5 0.0 11.0 4 2 7 11 11 11 9 PPR repeat family PPR PF01535.15 EME30788.1 - 1.8e-47 156.0 9.1 0.0001 21.9 0.0 12.9 13 0 0 13 13 13 10 PPR repeat PPR_3 PF13812.1 EME30788.1 - 1.5e-46 152.7 1.9 9.8e-05 22.3 0.0 13.9 14 0 0 14 14 14 11 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME30788.1 - 7e-46 153.3 10.9 6.6e-07 28.6 0.0 13.7 14 1 0 14 14 14 9 PPR repeat TPR_14 PF13428.1 EME30788.1 - 3.1e-07 30.4 0.2 2.6 8.8 0.0 7.4 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME30788.1 - 3.5e-07 30.7 0.0 3.3 8.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat MRP-S27 PF10037.4 EME30788.1 - 9.1e-06 24.8 7.5 0.1 11.4 0.1 4.2 2 2 3 5 5 5 3 Mitochondrial 28S ribosomal protein S27 TPR_12 PF13424.1 EME30788.1 - 1.3e-05 25.0 2.7 0.07 13.0 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME30788.1 - 2.2e-05 23.9 0.4 1 9.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME30788.1 - 0.0018 18.1 4.2 1.2 9.1 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.15 EME30788.1 - 0.0055 16.3 0.5 31 4.1 0.0 4.8 4 2 2 6 6 5 0 Region in Clathrin and VPS TPR_2 PF07719.12 EME30788.1 - 0.0083 15.9 2.1 20 5.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME30788.1 - 0.01 15.4 0.7 3.4 7.3 0.0 3.9 4 0 0 4 4 4 0 TPR repeat DUF3368 PF11848.3 EME30788.1 - 0.012 15.2 0.0 0.073 12.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) BTAD PF03704.12 EME30788.1 - 0.02 15.2 0.0 7.9 6.7 0.1 3.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Phage_DsbA PF11126.3 EME30788.1 - 0.051 13.6 0.1 5.2 7.2 0.0 3.4 4 0 0 4 4 4 0 Transcriptional regulator DsbA RRM_1 PF00076.17 EME30789.1 - 1.9e-10 40.2 0.0 3.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30789.1 - 1.9e-07 30.9 0.0 4.8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30789.1 - 1.9e-07 30.7 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HGTP_anticodon PF03129.15 EME30789.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain RRM_6 PF14259.1 EME30790.1 - 5.6e-61 202.4 0.1 1.4e-14 53.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME30790.1 - 5.6e-32 109.1 0.0 1.9e-07 30.6 0.0 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30790.1 - 4.9e-14 51.9 0.0 0.00016 21.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4478 PF14793.1 EME30791.1 - 0.15 11.6 0.1 0.29 10.7 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4478) TP6A_N PF04406.9 EME30795.1 - 1.2e-06 28.0 0.2 6.9e-05 22.4 0.1 2.7 1 1 0 1 1 1 1 Type IIB DNA topoisomerase DUF2220 PF09983.4 EME30795.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2220 PF09983.4 EME30796.1 - 0.017 14.3 0.1 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Lactamase_B_2 PF12706.2 EME30797.1 - 1.4e-37 129.1 0.7 1.7e-37 128.8 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME30797.1 - 4.2e-19 68.8 0.0 5.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME30797.1 - 0.1 12.2 1.8 0.68 9.5 1.0 2.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Adaptin_N PF01602.15 EME30798.1 - 9e-143 476.3 8.9 1.7e-142 475.4 6.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EME30798.1 - 2.8e-29 102.2 2.1 1.8e-24 86.5 0.0 4.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EME30798.1 - 2.3e-20 72.6 2.1 1.7e-06 28.1 0.0 6.0 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EME30798.1 - 5e-10 38.6 10.7 0.015 15.3 0.0 8.5 11 0 0 11 11 11 3 HEAT repeat B2-adapt-app_C PF09066.5 EME30798.1 - 9e-09 35.2 0.0 3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.1 EME30798.1 - 0.00069 20.0 6.8 3.8 8.1 0.1 6.2 5 2 2 7 7 7 1 HEAT-like repeat Arm PF00514.18 EME30798.1 - 0.0044 16.8 0.1 1.2 9.0 0.0 4.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EME30798.1 - 0.0067 15.8 0.3 0.21 10.9 0.0 3.2 4 0 0 4 4 4 1 CLASP N terminal MFS_1 PF07690.11 EME30799.1 - 1.6e-11 43.5 42.9 2.7e-06 26.3 14.0 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME30799.1 - 4.8e-09 35.1 21.8 9.5e-07 27.5 3.6 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 EME30800.1 - 5.1e-12 45.1 42.0 5e-11 41.9 29.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME30800.1 - 9e-09 34.2 22.9 3.7e-07 28.9 15.8 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein Ribul_P_3_epim PF00834.14 EME30801.1 - 2.7e-89 297.5 0.1 3.3e-89 297.3 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 EME30801.1 - 0.0038 16.4 3.4 0.85 8.8 0.1 2.5 2 1 1 3 3 3 2 PcrB family CmcH_NodU PF02543.10 EME30802.1 - 5e-63 213.3 0.0 2.3e-62 211.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase Peptidase_M22 PF00814.20 EME30802.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycoprotease family Glyco_transf_11 PF01531.11 EME30803.1 - 2.2e-11 43.2 0.0 3.9e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 11 RRM_1 PF00076.17 EME30804.1 - 5.6e-16 57.9 0.1 8.8e-16 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30804.1 - 4.7e-10 39.3 0.0 8.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30804.1 - 6.3e-08 32.3 0.4 1.1e-07 31.5 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EME30804.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ABC_tran PF00005.22 EME30807.1 - 3.6e-36 124.4 0.0 1e-35 123.0 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 EME30807.1 - 9.8e-25 87.4 6.4 1.3e-24 87.1 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EME30807.1 - 1e-07 31.4 0.0 6.9e-05 22.1 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME30807.1 - 1.1e-07 32.1 0.7 1.2e-05 25.4 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EME30807.1 - 2.2e-06 27.5 0.1 9.9e-05 22.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME30807.1 - 9.1e-06 25.7 0.0 3.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME30807.1 - 0.00016 21.8 0.1 0.002 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME30807.1 - 0.00081 20.2 0.0 0.0034 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME30807.1 - 0.0015 18.0 0.0 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EME30807.1 - 0.0015 17.7 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EME30807.1 - 0.0049 17.1 0.0 0.052 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EME30807.1 - 0.0096 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EME30807.1 - 0.011 15.4 0.0 0.089 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EME30807.1 - 0.022 14.9 0.0 0.24 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EME30807.1 - 0.023 13.7 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.20 EME30807.1 - 0.04 13.4 0.1 0.31 10.5 0.1 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EME30807.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EME30807.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME30807.1 - 0.074 12.4 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EME30807.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EME30807.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF572 PF04502.8 EME30808.1 - 7.5e-82 275.1 15.4 9.2e-82 274.8 10.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 EME30808.1 - 0.014 14.6 0.6 0.014 14.6 0.4 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.14 EME30808.1 - 0.025 14.2 1.5 0.61 9.7 0.0 2.8 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Zn_ribbon_recom PF13408.1 EME30808.1 - 0.096 12.9 6.7 3.3 8.0 0.1 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 EME30808.1 - 0.13 11.7 0.9 7.6 6.0 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EME30808.1 - 0.16 11.5 0.8 18 5.0 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_1c PF00749.16 EME30810.1 - 3e-100 334.9 0.0 4e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EME30810.1 - 2.6e-31 108.6 0.5 4.4e-31 107.8 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.20 EME30810.1 - 2.8e-05 24.0 0.0 8.5e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME30810.1 - 0.00023 21.5 0.0 0.00068 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME30810.1 - 0.0095 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SSB PF00436.20 EME30811.1 - 0.0048 16.7 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Choline_kinase PF01633.15 EME30812.1 - 5.9e-54 182.8 0.0 8.5e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EME30812.1 - 1.4e-12 47.8 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME30813.1 - 6.6e-54 182.6 0.0 9.7e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EME30813.1 - 1.6e-12 47.6 0.0 2.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ALIX_LYPXL_bnd PF13949.1 EME30814.1 - 0.057 12.3 0.7 0.094 11.6 0.2 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF919 PF06034.6 EME30814.1 - 1.9 8.1 6.2 0.52 9.9 1.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RNase_PH PF01138.16 EME30815.1 - 9.5e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 WD40 PF00400.27 EME30816.1 - 2.7e-23 80.9 9.2 3.8e-06 26.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF818 PF05677.7 EME30817.1 - 2.5 6.7 8.7 0.11 11.1 2.2 1.4 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Sedlin_N PF04628.8 EME30818.1 - 3.9e-21 75.3 0.0 4.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EME30818.1 - 9.5e-07 28.6 0.1 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family HIG_1_N PF04588.8 EME30819.1 - 8.6e-16 57.4 3.6 1.3e-15 56.8 2.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Claudin_2 PF13903.1 EME30819.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NfeD PF01957.13 EME30819.1 - 0.061 13.4 0.1 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Multi_Drug_Res PF00893.14 EME30820.1 - 1.8e-18 66.7 6.3 1.8e-18 66.7 4.3 1.4 1 1 0 1 1 1 1 Small Multidrug Resistance protein Sugar_transport PF06800.7 EME30820.1 - 5.6e-05 22.3 5.1 6.5e-05 22.1 3.6 1.1 1 0 0 1 1 1 1 Sugar transport protein Mg_trans_NIPA PF05653.9 EME30820.1 - 0.017 14.0 0.5 0.017 14.0 0.3 1.8 1 1 1 2 2 2 0 Magnesium transporter NIPA EmrE PF13536.1 EME30820.1 - 0.028 14.5 14.2 0.05 13.8 9.8 1.4 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EME30820.1 - 0.029 13.4 0.7 0.15 11.1 0.2 2.1 1 1 0 1 1 1 0 Nucleotide-sugar transporter UPF0546 PF10639.4 EME30820.1 - 0.052 13.3 2.0 0.068 12.9 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EME30820.1 - 0.078 12.6 9.8 0.14 11.7 6.8 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family SKG6 PF08693.5 EME30820.1 - 0.11 11.8 2.4 2.2 7.6 0.4 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EamA PF00892.15 EME30820.1 - 0.15 12.0 14.1 0.4 10.7 7.1 2.1 1 1 1 2 2 2 0 EamA-like transporter family UPF0060 PF02694.10 EME30820.1 - 0.58 10.2 6.4 0.71 9.9 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2207 PF09972.4 EME30820.1 - 9.1 4.7 6.3 6.2 5.2 3.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_6 PF12697.2 EME30821.1 - 1.9e-33 116.2 0.0 2.4e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME30821.1 - 2.1e-19 70.0 0.0 2.8e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME30821.1 - 7.3e-12 45.2 0.0 2.6e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME30821.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase MVP_shoulder PF11978.3 EME30821.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.5 2 0 0 2 2 2 0 Shoulder domain EHN PF06441.7 EME30821.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ndr PF03096.9 EME30821.1 - 0.077 11.4 0.0 2 6.8 0.0 2.1 2 0 0 2 2 2 0 Ndr family Chlorophyllase PF07224.6 EME30821.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.8 EME30821.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein BRO1 PF03097.13 EME30822.1 - 4.9e-41 140.7 0.1 4.9e-41 140.7 0.1 2.4 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EME30822.1 - 9.4e-23 80.6 18.3 9.4e-23 80.6 12.7 2.6 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV MitMem_reg PF13012.1 EME30822.1 - 9.2 6.3 16.1 0.28 11.2 2.3 4.4 6 1 0 6 6 6 0 Maintenance of mitochondrial structure and function Sas10_Utp3 PF04000.10 EME30823.1 - 2e-17 63.1 1.1 3.3e-17 62.4 0.8 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ribosomal_S18 PF01084.15 EME30823.1 - 0.0089 15.8 0.6 0.017 14.9 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Oxidored_nitro PF00148.14 EME30823.1 - 0.013 14.1 0.1 0.015 13.9 0.1 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Fungal_trans_2 PF11951.3 EME30823.1 - 0.038 12.5 0.1 0.039 12.5 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 EME30824.1 - 6.9e-38 130.0 16.8 8.8e-38 129.7 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 EME30825.1 - 6.9e-38 130.0 16.8 8.8e-38 129.7 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_S21 PF01165.15 EME30826.1 - 8.1e-17 60.4 5.7 1.4e-16 59.6 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 UDPG_MGDP_dh_N PF03721.9 EME30827.1 - 1.5e-53 180.9 0.0 2.5e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EME30827.1 - 1.2e-33 115.2 0.0 2.6e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EME30827.1 - 6.3e-30 103.4 0.0 3.9e-27 94.4 0.0 2.6 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EME30827.1 - 0.017 14.8 0.0 0.27 10.9 0.0 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CENP-X PF09415.5 EME30828.1 - 1.4e-13 50.4 0.5 1.6e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X WD40 PF00400.27 EME30829.1 - 8.4e-43 142.7 4.7 1.1e-08 34.6 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME30829.1 - 8.4e-05 21.4 1.4 0.00027 19.8 1.0 1.8 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 EME30829.1 - 0.0033 17.1 0.0 1.2 8.8 0.1 2.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME30829.1 - 0.0059 14.8 1.9 0.87 7.6 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BetaGal_dom2 PF10435.4 EME30829.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 EMG1 PF03587.9 EME30830.1 - 1.9e-62 210.1 0.1 2.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase bZIP_1 PF00170.16 EME30831.1 - 7.8e-05 22.5 13.8 0.00017 21.4 5.2 2.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME30831.1 - 0.0002 21.1 2.9 0.0002 21.1 2.0 2.6 2 0 0 2 2 2 1 Basic region leucine zipper FAM165 PF14981.1 EME30831.1 - 0.018 14.5 0.3 0.04 13.4 0.2 1.5 1 0 0 1 1 1 0 FAM165 family DUF3287 PF11690.3 EME30831.1 - 0.26 11.3 10.2 2.4 8.2 6.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF3020 PF11223.3 EME30831.1 - 1 9.7 5.4 0.66 10.4 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) SPX PF03105.14 EME30831.1 - 9.2 5.9 13.6 15 5.2 9.4 1.5 1 1 0 1 1 1 0 SPX domain Hemerythrin PF01814.18 EME30832.1 - 1.2e-05 25.4 4.6 3.3e-05 24.0 3.1 1.8 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain NUDIX PF00293.23 EME30833.1 - 2.8e-19 69.1 0.0 3.3e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DNA_pol_E_B PF04042.11 EME30835.1 - 2.5e-43 147.7 0.0 3.5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B POT1 PF02765.12 EME30836.1 - 1.4e-12 47.7 0.0 2.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 HIT PF01230.18 EME30837.1 - 1.9e-29 102.0 0.0 3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME30837.1 - 4.1e-27 94.7 0.0 5.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Consortin_C PF15281.1 EME30838.1 - 0.12 11.8 0.9 0.29 10.6 0.6 1.6 1 0 0 1 1 1 0 Consortin C-terminus DUF3452 PF11934.3 EME30839.1 - 0.15 11.4 0.5 0.24 10.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) PAC2 PF09754.4 EME30840.1 - 1.1e-15 58.0 0.0 6.6e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 PAC2 family Cu-oxidase_3 PF07732.10 EME30841.1 - 7.4e-08 32.1 0.0 2.7e-05 23.8 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME30841.1 - 3e-06 26.7 0.0 0.0026 17.2 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EME30841.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Rhodanese PF00581.15 EME30842.1 - 1.3e-16 60.9 0.0 1.6e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain 2OG-FeII_Oxy_2 PF13532.1 EME30843.1 - 1.9e-10 40.8 0.0 2.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME30843.1 - 2.2e-06 27.8 0.0 4.4e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SH2_2 PF14633.1 EME30844.1 - 6.8e-33 113.5 0.0 1.8e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EME30844.1 - 8.1e-18 64.6 0.0 8.1e-18 64.6 0.0 4.7 4 1 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 EME30844.1 - 6.9e-14 51.8 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EME30844.1 - 2.2e-12 47.0 8.6 5.6e-12 45.7 5.0 2.4 1 1 1 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EME30844.1 - 5.9e-06 26.3 19.6 5.9e-06 26.3 13.6 7.0 7 2 1 8 8 8 1 Acidic N-terminal SPT6 SH2 PF00017.19 EME30844.1 - 9e-06 25.4 0.0 2.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Myb_DNA-binding PF00249.26 EME30845.1 - 4.2e-11 42.7 0.0 8.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain GAS PF13851.1 EME30845.1 - 0.005 16.0 1.0 0.01 15.0 0.7 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Myb_DNA-bind_6 PF13921.1 EME30845.1 - 0.028 14.5 0.1 0.095 12.8 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain RRF PF01765.14 EME30846.1 - 0.03 13.7 0.6 0.042 13.3 0.4 1.2 1 0 0 1 1 1 0 Ribosome recycling factor COX5A PF02284.11 EME30846.1 - 0.072 13.0 1.6 3.3 7.7 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va Corona_nucleoca PF00937.13 EME30846.1 - 0.4 9.5 4.2 0.47 9.3 2.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pil1 PF13805.1 EME30846.1 - 0.8 8.7 5.2 1.1 8.3 3.4 1.4 1 1 0 1 1 1 0 Eisosome component PIL1 Calreticulin PF00262.13 EME30848.1 - 1e-152 508.1 5.3 1.5e-152 507.5 3.6 1.3 1 0 0 1 1 1 1 Calreticulin family DNA_pol_B PF00136.16 EME30849.1 - 3.5e-104 349.1 0.2 3.5e-104 349.1 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME30849.1 - 1.3e-20 73.5 0.1 1.3e-20 73.5 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EME30849.1 - 0.0014 18.0 1.6 0.0014 18.0 1.1 2.4 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger E1-E2_ATPase PF00122.15 EME30850.1 - 3.2e-41 140.8 0.0 5.5e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EME30850.1 - 2.5e-28 99.9 0.0 4.3e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME30850.1 - 1.3e-12 48.2 0.0 3.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EME30850.1 - 1.8e-08 34.3 0.6 5.6e-08 32.8 0.4 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EME30850.1 - 4.8e-06 26.3 0.0 1.2e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Oxidored_nitro PF00148.14 EME30850.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase GDI PF00996.13 EME30851.1 - 7.2e-55 186.0 0.1 7.7e-36 123.3 0.0 2.3 1 1 0 2 2 2 2 GDP dissociation inhibitor Lycopene_cycl PF05834.7 EME30851.1 - 0.001 18.0 0.2 0.72 8.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EME30851.1 - 0.0022 18.0 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME30851.1 - 0.013 14.4 0.0 0.65 8.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME30851.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME30851.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S8 PF00410.14 EME30852.1 - 5.3e-27 94.1 0.0 6.6e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Cyclin_N PF00134.18 EME30853.1 - 5.3e-43 145.6 1.4 1e-42 144.7 1.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME30853.1 - 2.6e-19 69.2 0.5 6.6e-19 67.9 0.2 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cse1 PF08506.5 EME30853.1 - 0.00035 19.2 0.3 0.00051 18.7 0.2 1.2 1 0 0 1 1 1 1 Cse1 Na_H_Exchanger PF00999.16 EME30854.1 - 2.5e-35 121.7 45.2 3.3e-35 121.3 31.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1318 PF07027.7 EME30854.1 - 0.034 14.3 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) Phage_holin_3 PF05106.7 EME30854.1 - 0.051 13.5 1.9 0.17 11.9 1.3 1.9 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Myco_arth_vir_N PF09610.5 EME30854.1 - 0.054 13.4 2.4 0.22 11.4 1.7 2.1 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) MbeB_N PF04837.7 EME30855.1 - 0.091 12.8 0.3 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Chorein_N PF12624.2 EME30857.1 - 1.2e-21 76.4 0.7 3.6e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter GAS PF13851.1 EME30857.1 - 0.26 10.4 17.8 0.5 9.5 12.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EME30857.1 - 0.6 9.6 12.8 1.1 8.8 8.9 1.3 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EME30857.1 - 0.69 10.3 11.3 0.24 11.8 2.7 2.7 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EME30857.1 - 2 7.3 15.4 3.6 6.5 10.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EME30857.1 - 2.6 7.9 22.9 5.7 6.8 6.8 3.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EME30857.1 - 3.4 7.6 13.2 0.38 10.7 0.7 2.8 2 0 0 2 2 2 0 FlxA-like protein TPR_MLP1_2 PF07926.7 EME30857.1 - 4.5 7.0 20.5 0.51 10.0 9.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ribosomal_S3Ae PF01015.13 EME30858.1 - 1.4e-79 266.0 0.7 1.6e-79 265.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EME30858.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3237 PF11578.3 EME30858.1 - 0.11 11.7 0.1 0.34 10.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3237) Ribosomal_S3Ae PF01015.13 EME30859.1 - 1.4e-79 266.0 0.7 1.6e-79 265.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EME30859.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3237 PF11578.3 EME30859.1 - 0.11 11.7 0.1 0.34 10.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3237) DASH_Dad2 PF08654.5 EME30860.1 - 0.001 19.0 0.7 0.0011 18.9 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 BLOC1_2 PF10046.4 EME30860.1 - 0.033 14.3 0.4 0.12 12.5 0.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2360 PF10152.4 EME30860.1 - 0.037 14.2 0.4 0.042 14.1 0.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Nsp1_C PF05064.8 EME30860.1 - 0.066 12.8 1.1 0.081 12.5 0.8 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF16 PF01519.11 EME30860.1 - 0.1 12.8 1.9 0.12 12.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.15 EME30860.1 - 0.11 12.2 1.3 0.21 11.3 0.2 1.4 1 1 0 1 1 1 0 Prefoldin subunit SYCE1 PF15233.1 EME30860.1 - 0.11 12.4 3.7 0.13 12.1 2.6 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 ADIP PF11559.3 EME30860.1 - 0.47 10.3 5.5 0.51 10.2 3.8 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EME30860.1 - 0.98 8.9 3.8 1 8.8 2.6 1.0 1 0 0 1 1 1 0 IncA protein PsbW PF07123.7 EME30861.1 - 7.6e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) MBT PF02820.13 EME30861.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 mbt repeat Peptidase_M24 PF00557.19 EME30862.1 - 2.6e-48 164.3 0.1 3.3e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1510 PF07423.6 EME30862.1 - 0.75 9.1 9.3 1.6 8.0 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Aminotran_5 PF00266.14 EME30863.1 - 3.3e-139 463.7 0.0 3.7e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME30863.1 - 7.1e-06 24.5 0.1 4.8e-05 21.8 0.0 2.1 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME30863.1 - 0.0079 15.2 0.1 0.015 14.3 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Rpr2 PF04032.11 EME30864.1 - 3.2e-19 68.5 0.2 4.3e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Fer4_10 PF13237.1 EME30864.1 - 0.014 15.1 1.0 0.021 14.6 0.7 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain GFA PF04828.9 EME30864.1 - 0.065 13.1 4.3 0.082 12.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-3CxxC PF13695.1 EME30864.1 - 0.31 11.2 3.9 0.5 10.6 2.7 1.3 1 0 0 1 1 1 0 Zinc-binding domain zf-Dof PF02701.10 EME30864.1 - 0.5 10.3 11.4 0.078 12.9 1.1 2.3 1 1 1 2 2 2 0 Dof domain, zinc finger AP-5_subunit_s1 PF15001.1 EME30865.1 - 0.039 13.9 0.5 0.039 13.9 0.4 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 UPF0197 PF05251.7 EME30866.1 - 2.2e-05 24.6 0.4 2.5e-05 24.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) MIG-14_Wnt-bd PF06664.7 EME30866.1 - 0.00023 20.0 1.2 0.00024 20.0 0.9 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion PgaD PF13994.1 EME30866.1 - 0.015 14.8 4.7 0.016 14.7 3.3 1.1 1 0 0 1 1 1 0 PgaD-like protein Pmp3 PF01679.12 EME30866.1 - 0.017 14.8 0.2 0.068 12.8 0.1 1.9 1 1 0 1 1 1 0 Proteolipid membrane potential modulator DUF308 PF03729.8 EME30866.1 - 0.065 13.2 8.4 0.08 12.9 5.8 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) RseC_MucC PF04246.7 EME30866.1 - 0.12 11.9 2.3 0.15 11.6 1.6 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF1469 PF07332.6 EME30866.1 - 0.9 9.2 6.0 1.2 8.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ribosomal_S7e PF01251.13 EME30867.1 - 5.3e-65 218.4 2.5 6e-65 218.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-CCCH PF00642.19 EME30868.1 - 5.1e-23 80.2 14.8 2.5e-12 46.1 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME30868.1 - 0.015 15.3 12.9 0.35 10.9 2.5 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EME30869.1 - 5.1e-23 80.2 14.8 2.5e-12 46.1 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME30869.1 - 0.015 15.3 12.9 0.35 10.9 2.5 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DWNN PF08783.6 EME30870.1 - 8.2e-22 76.9 2.4 1.5e-21 76.0 0.1 2.3 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EME30870.1 - 3e-05 23.3 9.5 5.6e-05 22.5 6.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EME30870.1 - 3.1e-05 23.6 0.1 6.4e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3895 PF13034.1 EME30870.1 - 0.037 13.4 0.2 0.08 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) zf-CCHC PF00098.18 EME30870.1 - 0.068 13.1 8.2 0.12 12.3 5.7 1.4 1 0 0 1 1 1 0 Zinc knuckle GIDA PF01134.17 EME30870.1 - 0.07 11.9 0.5 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MutS_V PF00488.16 EME30871.1 - 1.4e-36 126.0 0.0 3.1e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME30871.1 - 4e-07 30.0 4.3 8.4e-07 28.9 0.1 2.4 2 0 0 2 2 2 1 MutS domain III Smr PF01713.16 EME30871.1 - 1e-06 28.8 0.0 3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain GAS PF13851.1 EME30871.1 - 0.004 16.3 13.3 0.004 16.3 9.2 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF2407_C PF13373.1 EME30871.1 - 0.0095 15.8 7.4 0.022 14.6 3.1 2.4 2 0 0 2 2 2 1 DUF2407 C-terminal domain Phage_GP20 PF06810.6 EME30871.1 - 0.11 11.8 8.6 0.29 10.5 6.0 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 EME30871.1 - 0.51 8.1 6.2 1.1 7.0 4.3 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EME30871.1 - 3.1 8.0 15.5 2.6 8.3 3.4 3.5 4 0 0 4 4 4 0 AAA domain WD40 PF00400.27 EME30872.1 - 0.051 13.4 3.0 4.6 7.2 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Aldo_ket_red PF00248.16 EME30873.1 - 1.3e-65 221.0 0.0 1.5e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LSM PF01423.17 EME30874.1 - 1.4e-19 69.4 0.1 1.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain PUA PF01472.15 EME30875.1 - 4.9e-17 61.4 0.3 7.3e-17 60.8 0.2 1.3 1 0 0 1 1 1 1 PUA domain Las1 PF04031.8 EME30876.1 - 1.3e-32 112.6 0.2 1.8e-32 112.1 0.2 1.2 1 0 0 1 1 1 1 Las1-like YxiJ PF14176.1 EME30876.1 - 0.19 11.8 0.8 1.2 9.2 0.3 2.0 2 0 0 2 2 2 0 YxiJ-like protein Oxysterol_BP PF01237.13 EME30877.1 - 2.8e-122 407.6 0.5 5.5e-122 406.6 0.4 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 EME30877.1 - 1.8e-11 44.1 0.0 4.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EME30877.1 - 2.1e-08 34.3 0.0 9.8e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EME30877.1 - 7.3e-07 29.1 0.0 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EME30877.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4146 PF13652.1 EME30877.1 - 0.069 12.9 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4146) zf-RING_2 PF13639.1 EME30878.1 - 1.3e-06 28.1 4.4 2.7e-06 27.0 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME30878.1 - 1.4e-06 28.2 5.7 2.8e-06 27.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30878.1 - 3.4e-06 26.6 3.2 6.5e-06 25.7 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME30878.1 - 4.1e-06 26.4 1.8 1.4e-05 24.7 1.0 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EME30878.1 - 2.6e-05 24.2 0.5 9.2e-05 22.4 0.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME30878.1 - 0.0001 21.8 5.1 0.00026 20.5 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30878.1 - 0.00014 21.4 3.5 0.0003 20.4 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EME30878.1 - 0.00037 20.2 1.9 0.00078 19.1 1.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EME30878.1 - 0.00091 18.6 1.3 0.0024 17.3 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EME30878.1 - 0.026 14.3 4.7 0.061 13.2 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EME30878.1 - 0.035 13.6 1.0 0.097 12.2 0.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EME30878.1 - 0.15 11.7 1.0 0.32 10.6 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EME30878.1 - 0.16 11.8 0.5 0.31 10.9 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger E1-E2_ATPase PF00122.15 EME30879.1 - 3.3e-61 206.2 8.7 3.3e-61 206.2 6.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME30879.1 - 6.5e-46 156.1 4.4 6.5e-46 156.1 3.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME30879.1 - 4.6e-31 108.9 0.0 5.9e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME30879.1 - 1.6e-19 69.6 0.0 3.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EME30879.1 - 1e-18 66.4 0.8 3e-18 65.0 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EME30879.1 - 2e-15 57.4 0.0 6.2e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME30879.1 - 4.8e-09 36.1 0.8 6e-06 26.0 0.1 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase RDD PF06271.7 EME30879.1 - 2.6 7.9 6.6 0.4 10.5 0.7 2.6 3 0 0 3 3 3 0 RDD family GRAM PF02893.15 EME30880.1 - 1.3e-07 30.9 0.0 2.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain PH_BEACH PF14844.1 EME30880.1 - 0.029 14.2 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DUF3945 PF13101.1 EME30880.1 - 0.04 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Complex1_LYR PF05347.10 EME30881.1 - 3.4e-05 23.5 1.2 6.1e-05 22.7 0.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME30881.1 - 0.00097 19.2 0.9 0.0018 18.4 0.6 1.4 1 0 0 1 1 1 1 Complex1_LYR-like TLC PF03219.9 EME30882.1 - 5.6e-204 678.1 15.6 7e-204 677.8 10.8 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter ERG4_ERG24 PF01222.12 EME30883.1 - 1.1e-89 301.0 27.1 1.3e-89 300.7 18.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EME30883.1 - 1.8e-07 30.7 4.8 3e-07 29.9 3.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Oligomerisation PF02410.10 EME30884.1 - 7.6e-21 74.0 0.1 1.7e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Oligomerisation domain DUF4079 PF13301.1 EME30885.1 - 8.4e-31 107.3 4.0 2.6e-30 105.7 2.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF373 PF04123.8 EME30885.1 - 0.0018 17.4 0.3 0.0022 17.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Cytochrom_B_N PF00033.14 EME30885.1 - 0.0027 17.1 1.7 0.0055 16.0 1.2 1.5 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB DUF1772 PF08592.6 EME30885.1 - 0.0095 15.6 0.1 0.042 13.5 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Ni_hydr_CYTB PF01292.15 EME30885.1 - 0.044 13.1 1.9 0.25 10.7 1.3 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4405 PF14358.1 EME30885.1 - 0.049 13.7 0.6 0.049 13.7 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF1206 PF06724.6 EME30885.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Abhydrolase_6 PF12697.2 EME30886.1 - 2.1e-10 40.8 0.0 3.6e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME30886.1 - 3.6e-09 36.5 0.0 4.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EME30886.1 - 7.1e-08 32.3 0.0 2.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EME30886.1 - 4e-07 29.8 0.0 1.9e-05 24.3 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EME30886.1 - 0.011 15.3 0.0 0.036 13.6 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase Ndr PF03096.9 EME30886.1 - 0.015 13.7 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Ribosomal_L21p PF00829.16 EME30887.1 - 2.2e-21 75.8 0.0 3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF218 PF02698.12 EME30890.1 - 1.4e-21 76.6 0.0 1.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Kelch_4 PF13418.1 EME30890.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Proteasome PF00227.21 EME30891.1 - 2.7e-47 160.5 0.5 3.3e-47 160.2 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Mito_carr PF00153.22 EME30892.1 - 1.3e-50 169.0 2.6 1.3e-20 72.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3783 PF12646.2 EME30892.1 - 0.14 11.9 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) DUF647 PF04884.9 EME30893.1 - 1e-72 244.3 0.1 1.3e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis tRNA-synt_2b PF00587.20 EME30894.1 - 4.7e-58 195.5 0.2 1e-57 194.4 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Amidohydro_3 PF07969.6 EME30894.1 - 1.1e-53 182.9 0.0 1.6e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family HGTP_anticodon PF03129.15 EME30894.1 - 1e-21 76.6 1.3 2.3e-21 75.5 0.1 2.3 2 0 0 2 2 2 1 Anticodon binding domain FKBP_C PF00254.23 EME30895.1 - 1.3e-13 50.7 0.0 2.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_transf_18 PF15024.1 EME30895.1 - 2.5e-06 26.1 8.2 3.5e-06 25.6 5.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Polyketide_cyc PF03364.15 EME30896.1 - 6e-17 61.8 0.5 1e-16 61.0 0.1 1.5 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EME30896.1 - 0.00066 19.8 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 EME30896.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) TPM PF04536.9 EME30897.1 - 6.3e-09 35.7 0.0 7.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Ribosomal_L34e PF01199.13 EME30898.1 - 7.7e-39 131.8 3.1 1e-38 131.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Lipoprotein_21 PF14041.1 EME30898.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 LppP/LprE lipoprotein Utp12 PF04003.7 EME30899.1 - 3.1e-16 59.2 0.6 8.6e-16 57.8 0.4 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EME30899.1 - 1.6e-10 40.4 1.7 0.0019 17.9 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat UTP15_C PF09384.5 EME30899.1 - 0.011 15.3 0.8 0.022 14.4 0.6 1.5 1 0 0 1 1 1 0 UTP15 C terminal Mucin PF01456.12 EME30899.1 - 0.39 10.4 2.6 0.39 10.5 0.6 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein GYF PF02213.11 EME30900.1 - 1.4e-12 46.9 0.1 4.6e-12 45.3 0.1 1.9 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 EME30900.1 - 0.009 15.5 0.1 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Abhydrolase_1 PF00561.15 EME30900.1 - 0.03 13.8 0.2 0.11 12.0 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF720 PF05302.6 EME30901.1 - 1.6 8.5 4.2 0.79 9.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF720) COMPASS-Shg1 PF05205.7 EME30901.1 - 2.3 8.5 7.1 5.3 7.3 4.9 1.7 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 ERCC4 PF02732.10 EME30902.1 - 5.1e-19 68.4 1.0 8.7e-18 64.4 0.1 2.7 2 0 0 2 2 2 1 ERCC4 domain ERCC4 PF02732.10 EME30903.1 - 7e-19 68.0 0.8 9.2e-18 64.3 0.1 2.7 2 0 0 2 2 2 1 ERCC4 domain Med7 PF05983.6 EME30904.1 - 0.0065 16.2 0.3 0.0077 16.0 0.2 1.2 1 0 0 1 1 1 1 MED7 protein Herpes_BTRF1 PF04682.7 EME30904.1 - 0.078 12.3 0.3 0.088 12.1 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region Arch_ATPase PF01637.13 EME30906.1 - 8.6e-05 22.3 0.0 0.00025 20.8 0.0 1.8 2 1 0 2 2 2 1 Archaeal ATPase RNA_pol_Rpb1_1 PF04997.7 EME30907.1 - 1.6e-102 343.2 0.0 6.9e-102 341.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EME30907.1 - 1.5e-70 236.4 0.0 1.7e-69 233.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EME30907.1 - 1.6e-52 177.4 0.0 3e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EME30907.1 - 2.4e-07 30.4 0.4 5.4e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_L30 PF00327.15 EME30908.1 - 0.0085 15.6 2.7 0.011 15.3 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30 PF00327.15 EME30909.1 - 0.0085 15.6 2.7 0.011 15.3 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RRM_1 PF00076.17 EME30910.1 - 2.8e-18 65.3 0.0 4.6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30910.1 - 4.2e-09 36.2 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30910.1 - 0.00033 20.4 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.13 EME30911.1 - 2.5e-48 164.5 16.2 2.5e-48 164.5 11.2 2.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DnaJ PF00226.26 EME30912.1 - 3.1e-25 87.6 0.7 8.6e-25 86.2 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME30912.1 - 1e-20 73.4 1.0 2.6e-17 62.4 0.0 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME30912.1 - 2e-15 56.5 18.9 3.3e-15 55.8 13.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EME30912.1 - 0.03 13.9 6.1 0.19 11.4 1.3 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EME30912.1 - 3.2 8.1 9.7 0.76 10.1 3.9 2.0 2 0 0 2 2 2 0 Cytochrome c3 zf-C3HC4 PF00097.20 EME30912.1 - 3.4 7.3 7.5 0.34 10.6 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30913.1 - 3e-11 42.8 7.1 6.7e-11 41.6 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30913.1 - 0.0047 16.6 8.3 0.012 15.2 5.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME30913.1 - 0.0078 16.2 10.0 0.017 15.1 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME30913.1 - 0.28 10.7 6.0 0.61 9.6 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EME30913.1 - 9.1 6.2 12.8 2.9 7.7 6.7 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 EME30914.1 - 6.8e-12 44.8 8.1 1.5e-11 43.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME30914.1 - 5.8e-05 23.0 9.6 0.00016 21.6 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30914.1 - 0.00014 21.4 8.0 0.00041 20.0 5.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EME30914.1 - 0.00096 18.9 8.7 0.0024 17.6 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 EME30914.1 - 0.0086 15.5 4.4 0.019 14.4 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.7 EME30914.1 - 1.1 9.1 7.9 0.13 12.0 2.2 2.0 2 0 0 2 2 2 0 zinc-ribbons GRAM PF02893.15 EME30915.1 - 3.5e-15 55.2 0.0 8e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF912 PF06024.7 EME30915.1 - 0.00045 20.2 0.1 0.00045 20.2 0.0 3.6 3 1 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EME30915.1 - 0.0065 16.1 0.2 0.0065 16.1 0.1 2.4 2 0 0 2 2 2 1 Rifin/stevor family YjgP_YjgQ PF03739.9 EME30915.1 - 0.018 13.7 1.0 0.052 12.2 0.1 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Pex26 PF07163.7 EME30915.1 - 0.032 13.1 0.3 0.032 13.1 0.2 2.6 3 1 1 4 4 4 0 Pex26 protein MFS_1 PF07690.11 EME30916.1 - 1.3e-28 99.7 31.2 1.3e-28 99.7 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3HC4_3 PF13920.1 EME30917.1 - 7.8e-08 31.8 14.0 7.8e-08 31.8 9.7 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Presenilin PF01080.12 EME30918.1 - 5.8e-32 111.0 3.7 5.8e-32 111.0 2.6 1.3 2 0 0 2 2 2 1 Presenilin Pkinase PF00069.20 EME30919.1 - 1e-65 221.4 0.0 1.3e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30919.1 - 8.7e-28 97.0 0.0 8.4e-27 93.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30919.1 - 1.7e-05 23.9 0.0 7.5e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME30919.1 - 0.075 12.3 0.4 0.36 10.1 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EME30919.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EME30920.1 - 1.1e-68 231.2 0.0 1.2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30920.1 - 4.1e-32 111.2 0.0 5.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30920.1 - 1.7e-05 23.9 0.0 0.00054 19.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EME30920.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EME30920.1 - 0.097 12.2 0.1 0.23 11.0 0.0 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase adh_short PF00106.20 EME30921.1 - 2.7e-31 108.7 0.0 3.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME30921.1 - 7e-14 51.8 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME30921.1 - 3.5e-13 49.9 0.2 4.6e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EME30921.1 - 0.0012 18.6 0.1 0.0029 17.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EME30921.1 - 0.0014 18.1 0.1 0.0023 17.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME30921.1 - 0.0027 16.6 0.1 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EME30921.1 - 0.016 14.2 0.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EME30921.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EME30921.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EME30921.1 - 0.039 14.0 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EME30921.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Proteasome PF00227.21 EME30922.1 - 6.5e-45 152.7 0.0 1.2e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME30922.1 - 2.9e-14 52.0 0.3 2.9e-14 52.0 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 EME30923.1 - 3e-50 166.3 23.0 1.2e-11 44.0 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EME30923.1 - 7.4e-21 74.7 0.7 1.3e-20 73.9 0.5 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EME30923.1 - 0.00027 20.6 0.1 0.001 18.7 0.0 2.0 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EME30923.1 - 0.0032 17.2 0.0 0.066 12.9 0.0 2.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A COX17 PF05051.8 EME30924.1 - 0.087 12.8 2.0 0.15 12.1 1.4 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 EME30924.1 - 0.24 11.5 2.2 0.27 11.3 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) HSF_DNA-bind PF00447.12 EME30925.1 - 2.7e-28 98.1 0.1 1e-27 96.2 0.0 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding DUF4611 PF15387.1 EME30925.1 - 0.43 10.7 10.5 1.6 8.9 7.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EME30925.1 - 0.75 9.3 9.0 1.6 8.2 6.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin eIF3_p135 PF12807.2 EME30925.1 - 0.97 9.3 5.7 0.3 11.0 0.9 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 NOA36 PF06524.7 EME30925.1 - 4.8 6.3 9.7 7.4 5.7 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein Arm PF00514.18 EME30926.1 - 1.3e-18 66.0 16.8 0.00035 20.2 0.0 8.9 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME30926.1 - 1.7e-13 50.6 2.3 0.015 15.5 0.0 6.2 4 3 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EME30926.1 - 4.9e-08 32.4 24.3 0.046 13.8 0.0 9.1 10 0 0 10 10 10 2 HEAT repeat V-ATPase_H_C PF11698.3 EME30926.1 - 6.2e-06 26.1 3.4 5.4 6.9 0.0 5.6 3 2 3 6 6 6 2 V-ATPase subunit H HEAT_EZ PF13513.1 EME30926.1 - 1.9e-05 25.0 8.3 14 6.3 0.0 7.1 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME30926.1 - 0.00015 22.0 3.1 3.8 7.9 0.0 5.5 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.4 EME30926.1 - 0.001 18.8 4.6 0.18 11.5 0.1 4.4 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DRIM PF07539.7 EME30926.1 - 0.0015 17.9 0.6 3.4 7.0 0.1 4.2 4 0 0 4 4 4 1 Down-regulated in metastasis DUF3361 PF11841.3 EME30926.1 - 0.046 13.4 2.8 4 7.1 0.2 4.2 3 1 1 5 5 5 0 Domain of unknown function (DUF3361) BRO1 PF03097.13 EME30927.1 - 1.3e-26 93.3 6.4 1.6e-26 92.9 4.4 1.0 1 0 0 1 1 1 1 BRO1-like domain FMN_red PF03358.10 EME30928.1 - 4.9e-15 55.3 0.0 7.4e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EME30928.1 - 1.1e-08 35.1 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EME30928.1 - 1.7e-08 34.2 0.1 3.4e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EME30928.1 - 0.0015 18.5 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Flavodoxin domain PDGF PF00341.12 EME30928.1 - 0.18 11.9 0.8 0.37 10.9 0.5 1.5 1 0 0 1 1 1 0 PDGF/VEGF domain SBF PF01758.11 EME30929.1 - 1.6e-34 118.9 18.0 1.6e-34 118.9 12.5 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF4137 PF13593.1 EME30929.1 - 1.4e-12 47.3 24.8 2.1e-12 46.8 17.2 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF204 PF02659.10 EME30929.1 - 2.2 8.4 12.1 0.85 9.7 0.2 4.3 1 1 1 3 3 3 0 Domain of unknown function DUF peroxidase PF00141.18 EME30930.1 - 6.5e-19 68.3 0.0 8.5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF4606 PF15379.1 EME30930.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF581 PF04570.9 EME30930.1 - 0.082 12.2 0.2 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Tim17 PF02466.14 EME30931.1 - 1.1e-33 115.9 3.7 1.8e-33 115.2 2.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1028 PF06267.7 EME30931.1 - 0.014 14.8 0.8 0.019 14.3 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Kinesin PF00225.18 EME30932.1 - 2.6e-107 358.4 4.8 2.6e-107 358.4 3.3 3.1 3 1 1 4 4 4 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 EME30932.1 - 0.0021 17.9 87.8 0.038 13.8 10.2 5.0 1 1 3 4 4 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EME30932.1 - 1.4 7.4 80.2 0.11 11.1 17.1 4.0 2 1 2 4 4 4 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EME30932.1 - 1.4 7.9 35.7 0.16 11.1 2.0 5.1 2 1 4 6 6 6 0 Reovirus sigma C capsid protein GAS PF13851.1 EME30932.1 - 2.1 7.5 86.0 0.047 12.8 14.5 4.8 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding NAD_binding_6 PF08030.7 EME30933.1 - 4.9e-15 55.7 0.0 1.4e-06 28.2 0.0 3.3 2 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EME30933.1 - 4.9e-14 52.0 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EME30933.1 - 1.4e-07 31.6 9.2 1.4e-07 31.6 6.4 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DnaJ PF00226.26 EME30934.1 - 4.2e-28 96.8 0.7 6.7e-28 96.2 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME30934.1 - 2.8e-22 78.4 0.2 4.3e-20 71.4 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME30934.1 - 1.6e-09 37.6 13.4 2.9e-09 36.8 9.3 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EME30935.1 - 4.2e-28 96.8 0.7 6.7e-28 96.2 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME30935.1 - 2.8e-22 78.4 0.2 4.3e-20 71.3 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME30935.1 - 1.6e-09 37.7 13.4 2.9e-09 36.8 9.3 1.5 1 0 0 1 1 1 1 DnaJ central domain HSP70 PF00012.15 EME30936.1 - 1.4e-269 895.1 13.5 1.5e-269 894.9 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME30936.1 - 2.9e-17 62.2 0.5 5e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EME30936.1 - 0.0073 15.9 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EME30936.1 - 0.026 13.6 9.3 0.054 12.5 0.1 3.5 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Pfg27 PF09216.5 EME30936.1 - 0.038 13.5 3.9 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 Pfg27 EST1_DNA_bind PF10373.4 EME30936.1 - 0.047 12.8 3.7 0.36 10.0 0.1 2.5 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain Dehydrin PF00257.14 EME30936.1 - 0.66 10.2 4.3 0.31 11.3 1.0 1.9 1 1 1 2 2 2 0 Dehydrin FtsA PF14450.1 EME30936.1 - 0.84 9.4 9.5 3.2 7.6 0.2 4.4 4 1 0 4 4 4 0 Cell division protein FtsA PAP_assoc PF03828.14 EME30937.1 - 9.9e-18 63.8 0.4 3.8e-12 45.9 0.0 2.9 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EME30937.1 - 0.0015 18.8 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pep3_Vps18 PF05131.9 EME30938.1 - 1.7e-18 66.4 0.7 1.1e-16 60.6 0.6 3.1 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EME30938.1 - 1.6e-14 53.7 0.8 1.6e-13 50.4 0.2 2.7 2 1 0 2 2 2 1 Region in Clathrin and VPS VanW PF04294.8 EME30938.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 VanW like protein DUF4050 PF13259.1 EME30939.1 - 0.2 11.5 3.8 0.46 10.4 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) DUF3526 PF12040.3 EME30939.1 - 2.1 8.5 5.2 38 4.3 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3526) NAP PF00956.13 EME30941.1 - 1.1e-23 83.6 5.6 1.8e-23 82.9 3.9 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Tex_N PF09371.5 EME30941.1 - 0.018 14.3 0.6 0.11 11.7 0.2 2.1 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Lipase_3 PF01764.20 EME30942.1 - 7.5e-27 93.6 0.1 1.9e-25 89.1 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EME30942.1 - 0.00034 20.0 3.0 0.002 17.5 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EME30942.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family NADHdh_A3 PF14987.1 EME30943.1 - 0.0043 16.9 0.9 0.006 16.4 0.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Gly_transf_sug PF04488.10 EME30944.1 - 2.7e-10 40.5 0.0 6.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EME30944.1 - 7.5e-05 22.0 0.2 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DLH PF01738.13 EME30945.1 - 1.9e-39 135.2 0.0 2.1e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME30945.1 - 6.4e-12 45.4 0.0 8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME30945.1 - 3e-10 40.3 0.5 2.4e-06 27.6 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family BAAT_C PF08840.6 EME30945.1 - 6.2e-07 29.3 0.1 0.00037 20.2 0.0 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EME30945.1 - 1.3e-05 24.5 0.1 0.0063 15.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EME30945.1 - 0.00024 20.7 0.2 0.51 9.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EME30945.1 - 0.00066 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EME30945.1 - 0.008 15.6 0.1 0.61 9.4 0.0 2.3 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.15 EME30945.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EME30945.1 - 0.011 14.2 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME30945.1 - 0.06 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EME30945.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_M1 PF01433.15 EME30946.1 - 0.017 14.2 1.4 0.032 13.3 0.1 2.1 2 1 0 2 2 2 0 Peptidase family M1 DNA_topoisoIV PF00521.15 EME30946.1 - 0.04 12.7 0.7 0.11 11.3 0.5 1.7 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Ribosomal_L35p PF01632.14 EME30947.1 - 3.8e-08 33.0 2.8 5.6e-08 32.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Acyl-CoA_dh_1 PF00441.19 EME30948.1 - 4.6e-46 156.6 0.6 7.6e-46 155.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME30948.1 - 1.3e-31 109.5 0.0 3.8e-31 108.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME30948.1 - 9.8e-21 74.4 0.0 1.6e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME30948.1 - 8.2e-16 57.2 0.1 1.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RIO1 PF01163.17 EME30949.1 - 3.8e-43 147.0 0.4 8.6e-43 145.8 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EME30949.1 - 6.1e-31 106.3 0.6 1.6e-30 105.0 0.1 1.9 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.9 EME30949.1 - 1e-09 37.7 0.1 3.2e-09 36.1 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME30949.1 - 8.6e-07 28.9 0.5 0.0032 17.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EME30949.1 - 2.9e-05 23.3 0.2 5.5e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EME30949.1 - 0.042 12.7 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like IL4Ra_N PF09238.5 EME30949.1 - 0.078 13.0 1.3 13 6.0 0.0 2.7 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal ALMT PF11744.3 EME30950.1 - 7.3e-05 21.5 7.0 0.005 15.5 0.2 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2422 PF10337.4 EME30950.1 - 0.00075 18.4 2.0 0.016 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EME30950.1 - 0.0011 18.6 0.0 0.17 11.4 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EME30950.1 - 0.0013 17.2 27.9 0.053 11.9 6.3 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family PhoU PF01895.14 EME30950.1 - 0.084 13.3 0.6 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 PhoU domain ABC_tran PF00005.22 EME30951.1 - 8.7e-25 87.6 0.0 1.8e-24 86.6 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EME30951.1 - 1.2e-14 55.0 3.3 1.4e-07 31.8 0.1 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EME30951.1 - 1.3e-06 27.8 0.1 0.041 13.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EME30951.1 - 0.00053 19.1 0.1 0.00089 18.4 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EME30951.1 - 0.0016 17.9 0.1 0.0054 16.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EME30951.1 - 0.0041 17.1 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EME30951.1 - 0.0072 15.5 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EME30951.1 - 0.01 16.0 0.0 0.074 13.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EME30951.1 - 0.012 15.9 0.2 0.02 15.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME30951.1 - 0.035 14.6 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 EME30951.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME30951.1 - 0.037 14.1 0.0 0.067 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME30951.1 - 0.069 13.0 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EME30951.1 - 0.075 11.9 0.0 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EME30951.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EME30951.1 - 0.091 12.1 0.1 0.33 10.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EME30951.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Dynamin family DNA_pol_A PF00476.15 EME30952.1 - 2.2e-40 138.4 0.2 3.1e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.11 EME30952.1 - 4e-38 130.4 0.0 9.8e-38 129.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EME30952.1 - 1e-25 89.8 0.0 3e-25 88.3 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Prefoldin_2 PF01920.15 EME30953.1 - 4.7e-20 71.3 13.7 6.1e-20 70.9 9.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 EME30953.1 - 0.013 15.2 2.9 0.013 15.2 2.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 TBPIP PF07106.8 EME30953.1 - 0.036 13.6 9.6 0.66 9.5 1.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF648 PF04890.8 EME30953.1 - 0.055 12.6 0.2 0.055 12.6 0.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF648) MecA_N PF05223.6 EME30953.1 - 0.085 12.9 3.3 0.1 12.6 0.6 1.9 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain Syntaxin-6_N PF09177.6 EME30953.1 - 0.22 11.9 6.4 2.7 8.4 0.4 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EME30953.1 - 0.23 11.2 5.4 0.19 11.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lge1 PF11488.3 EME30953.1 - 0.25 11.5 8.0 3.5 7.8 0.3 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2605 PF10792.4 EME30953.1 - 0.34 10.6 2.4 0.27 10.9 0.5 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2605) DUF4404 PF14357.1 EME30953.1 - 0.54 10.6 7.2 1.8 9.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SlyX PF04102.7 EME30953.1 - 0.69 10.3 7.1 0.94 9.8 0.9 2.4 2 0 0 2 2 2 0 SlyX DUF342 PF03961.8 EME30953.1 - 0.82 8.0 7.4 0.96 7.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaG PF03646.10 EME30953.1 - 1.6 8.9 8.9 5.8 7.0 0.3 2.2 2 0 0 2 2 2 0 FlaG protein DUF641 PF04859.7 EME30953.1 - 2 8.1 8.8 0.38 10.4 2.0 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Med9 PF07544.8 EME30953.1 - 2.3 7.9 8.5 0.98 9.1 0.9 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ORF6C PF10552.4 EME30953.1 - 2.5 7.8 9.4 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 ORF6C domain DUF2935 PF11155.3 EME30953.1 - 3.5 7.7 7.3 6.9 6.7 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF1657 PF07870.6 EME30953.1 - 3.9 7.2 6.0 20 4.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Allexi_40kDa PF05549.6 EME30953.1 - 4.7 6.4 7.7 1.6 7.9 0.7 2.0 1 1 0 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 EME30953.1 - 8.6 5.9 18.4 1.4e+02 1.9 12.8 2.0 1 1 0 1 1 1 0 IncA protein HisG PF01634.13 EME30954.1 - 2.7e-37 127.8 0.0 1.5e-35 122.1 0.0 2.1 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EME30954.1 - 6.1e-12 45.3 0.0 9.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain RE_XcyI PF09571.5 EME30954.1 - 0.042 12.6 0.1 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease LysR_substrate PF03466.15 EME30954.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain OB_NTP_bind PF07717.11 EME30955.1 - 1e-19 70.4 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME30955.1 - 1.8e-15 56.7 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME30955.1 - 1.6e-13 50.3 0.1 9.5e-13 47.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME30955.1 - 6.5e-10 38.7 0.3 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EME30955.1 - 9.1e-05 21.4 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EME30955.1 - 0.00033 20.7 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME30955.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME30955.1 - 0.014 15.1 0.3 0.21 11.3 0.3 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_11 PF13086.1 EME30955.1 - 0.017 14.6 0.0 0.23 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EME30955.1 - 0.019 13.8 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 EME30955.1 - 0.079 12.7 0.3 11 5.8 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EME30955.1 - 0.13 12.6 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AMMECR1 PF01871.12 EME30956.1 - 8.3e-43 145.4 0.0 1e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 zf-RING_2 PF13639.1 EME30957.1 - 3.6e-14 52.3 5.1 9.6e-14 50.9 3.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME30957.1 - 2.4e-08 33.5 2.6 6.5e-08 32.1 1.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME30957.1 - 5.4e-08 32.7 6.2 5.4e-08 32.7 4.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME30957.1 - 2.5e-07 30.2 4.8 2.5e-07 30.2 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME30957.1 - 2.8e-07 30.5 9.0 8.5e-07 29.0 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME30957.1 - 4.7e-07 29.3 2.7 4.7e-07 29.3 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME30957.1 - 0.51 10.2 8.3 0.42 10.4 4.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EME30957.1 - 5.6 6.7 8.6 1.3 8.7 3.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Endosulfine PF04667.12 EME30958.1 - 4.5e-11 42.5 1.7 6e-11 42.1 0.8 1.6 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF485 PF04341.7 EME30959.1 - 0.53 10.0 3.7 1.3 8.8 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Transposase_28 PF04195.7 EME30959.1 - 0.94 8.7 4.6 2.3 7.5 3.2 1.6 1 0 0 1 1 1 0 Putative gypsy type transposon DUF485 PF04341.7 EME30960.1 - 0.53 10.0 3.7 1.3 8.8 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Transposase_28 PF04195.7 EME30960.1 - 0.94 8.7 4.6 2.3 7.5 3.2 1.6 1 0 0 1 1 1 0 Putative gypsy type transposon Ribosomal_L17 PF01196.14 EME30961.1 - 2.4e-36 124.1 0.2 3.8e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 MIF PF01187.13 EME30962.1 - 6.9e-26 90.5 0.0 7.6e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EME30962.1 - 0.0018 17.8 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme PP-binding PF00550.20 EME30963.1 - 1.8e-12 47.3 0.1 2.1e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EME30963.1 - 4.7e-05 23.3 0.1 5.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EME30963.1 - 0.00012 22.1 0.1 0.00014 21.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) PP-binding PF00550.20 EME30964.1 - 6.1e-12 45.6 0.1 9.8e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EME30964.1 - 0.00019 21.3 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EME30964.1 - 0.00034 20.6 0.1 0.00063 19.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) GST_N_3 PF13417.1 EME30965.1 - 5.7e-20 71.3 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME30965.1 - 4.8e-14 52.1 0.0 9.9e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME30965.1 - 1.1e-13 51.1 0.0 1.4e-12 47.6 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME30965.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EME30965.1 - 0.0024 17.8 0.0 0.016 15.1 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin GST_C_2 PF13410.1 EME30965.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME30965.1 - 0.0063 16.9 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tropomodulin PF03250.9 EME30965.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Tropomodulin HCO3_cotransp PF00955.16 EME30966.1 - 3.4 6.2 5.3 0.43 9.1 0.2 1.9 2 0 0 2 2 2 0 HCO3- transporter family SseC PF04888.7 EME30966.1 - 3.4 6.9 7.5 0.17 11.1 0.2 2.3 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Tmemb_14 PF03647.8 EME30967.1 - 2.2e-17 63.2 14.2 2.3e-17 63.1 9.1 1.6 2 0 0 2 2 2 1 Transmembrane proteins 14C TMEM237 PF15383.1 EME30967.1 - 0.046 12.8 2.9 0.055 12.5 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3309 PF11752.3 EME30967.1 - 0.072 12.8 1.6 0.11 12.2 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3353 PF11833.3 EME30967.1 - 0.41 10.0 6.1 0.58 9.5 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) MerC PF03203.9 EME30967.1 - 0.58 10.5 7.8 0.27 11.6 3.0 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.1 EME30967.1 - 0.86 8.9 6.1 0.4 10.0 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PPR PF01535.15 EME30968.1 - 1.2e-13 49.9 5.6 0.013 15.4 0.2 5.6 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 EME30968.1 - 2.2e-12 46.7 3.3 0.0015 18.4 0.0 5.2 1 1 4 5 5 5 5 PPR repeat family PPR_3 PF13812.1 EME30968.1 - 2.8e-12 45.8 0.6 0.017 15.3 0.0 5.6 5 0 0 5 5 5 3 Pentatricopeptide repeat domain TPR_1 PF00515.23 EME30968.1 - 0.00052 19.4 0.2 8.6 6.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.2 EME30968.1 - 0.0012 18.3 0.4 3.7 7.0 0.1 4.3 5 0 0 5 5 5 1 PPR repeat TPR_12 PF13424.1 EME30968.1 - 0.0013 18.6 0.6 0.46 10.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME30968.1 - 0.0017 18.9 0.0 1.6 9.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EME30968.1 - 0.0021 18.1 1.9 0.15 12.2 0.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME30968.1 - 0.0046 17.2 0.1 3.3 8.1 0.0 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME30968.1 - 0.0056 16.3 0.2 2.9 7.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME30968.1 - 0.044 13.6 1.4 11 6.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 EME30968.1 - 0.067 12.7 2.7 0.41 10.2 0.4 2.7 2 1 1 3 3 3 0 Region in Clathrin and VPS BTAD PF03704.12 EME30968.1 - 0.083 13.1 0.2 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain COX5A PF02284.11 EME30968.1 - 0.12 12.3 0.0 5.2 7.0 0.0 2.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va VP9 PF09625.5 EME30968.1 - 0.18 11.6 0.6 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 VP9 protein PPR PF01535.15 EME30969.1 - 1.5e-13 49.6 5.6 0.013 15.4 0.2 5.6 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.1 EME30969.1 - 2.6e-12 46.5 3.3 0.0016 18.3 0.0 5.1 1 1 4 5 5 5 5 PPR repeat family PPR_3 PF13812.1 EME30969.1 - 3.5e-12 45.5 0.6 0.017 15.3 0.0 5.5 5 0 0 5 5 5 3 Pentatricopeptide repeat domain TPR_1 PF00515.23 EME30969.1 - 0.00061 19.2 0.2 8.9 6.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.2 EME30969.1 - 0.0013 18.2 0.4 3.9 7.0 0.1 4.3 5 0 0 5 5 5 1 PPR repeat TPR_12 PF13424.1 EME30969.1 - 0.0015 18.4 0.6 0.48 10.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME30969.1 - 0.0019 18.8 0.0 1.7 9.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EME30969.1 - 0.0022 18.0 1.7 0.11 12.6 0.8 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME30969.1 - 0.0055 17.0 0.1 3.5 8.0 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME30969.1 - 0.0064 16.2 0.2 3 7.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME30969.1 - 0.046 13.6 1.3 11 6.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 EME30969.1 - 0.064 12.8 2.5 0.43 10.1 0.4 2.7 2 1 1 3 3 3 0 Region in Clathrin and VPS BTAD PF03704.12 EME30969.1 - 0.094 13.0 0.2 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Patatin PF01734.17 EME30970.1 - 4.6e-14 52.8 1.8 2.8e-12 47.0 0.9 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase adh_short PF00106.20 EME30973.1 - 2.3e-15 56.9 0.0 2.7e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME30973.1 - 3.2e-09 36.9 0.0 4.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME30973.1 - 3e-06 26.8 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME30973.1 - 0.002 17.8 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 KR domain eIF-5a PF01287.15 EME30974.1 - 9.8e-26 89.5 3.7 1.4e-25 88.9 2.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EME30974.1 - 0.0067 16.1 1.5 0.011 15.4 0.3 2.0 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EME30974.1 - 0.056 13.3 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain N2227 PF07942.7 EME30975.1 - 2.5e-88 295.5 0.1 3.5e-88 295.0 0.1 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EME30975.1 - 0.0011 18.7 0.0 0.0028 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME30975.1 - 0.0059 17.0 0.0 0.087 13.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME30975.1 - 0.012 16.2 0.0 0.038 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EME30975.1 - 0.013 14.9 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 EME30975.1 - 0.022 13.7 0.0 0.082 11.8 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EME30975.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ATP-synt_S1 PF05827.7 EME30975.1 - 0.051 12.8 0.1 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Methyltransf_11 PF08241.7 EME30975.1 - 0.15 12.5 0.0 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Sigma70_r3 PF04539.11 EME30976.1 - 3.5e-18 65.2 0.5 1e-08 34.9 0.0 3.6 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r2 PF04542.9 EME30976.1 - 8.2e-12 44.5 0.1 1.6e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EME30976.1 - 6.8e-11 41.3 1.3 6.2e-09 35.0 0.2 3.3 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EME30976.1 - 0.067 12.6 1.3 7.2 6.1 0.0 3.1 2 1 0 2 2 2 0 Sigma-70, region 4 Methyltransf_2 PF00891.13 EME30977.1 - 1.4e-51 175.0 0.0 1.9e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EME30977.1 - 0.0002 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EME30977.1 - 0.058 12.3 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.7 EME30977.1 - 0.074 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PP2C_C PF07830.8 EME30977.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain GidB PF02527.10 EME30977.1 - 0.13 11.3 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G LSM PF01423.17 EME30978.1 - 0.00099 18.6 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Vps53_N PF04100.7 EME30979.1 - 4.6e-70 236.3 8.0 9.6e-70 235.2 5.6 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 EME30979.1 - 5e-07 28.1 2.6 1.7e-06 26.4 1.2 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec6 COG7 PF10191.4 EME30979.1 - 1.2e-06 26.7 0.7 1.2e-06 26.7 0.5 2.9 2 1 0 2 2 2 1 Golgi complex component 7 (COG7) DUF2450 PF10475.4 EME30979.1 - 0.0041 16.0 5.5 0.0041 16.0 3.8 2.1 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) DUF1400 PF07176.6 EME30979.1 - 0.13 12.1 2.0 0.24 11.3 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) RRM_1 PF00076.17 EME30980.1 - 2.6e-31 107.0 0.0 1.6e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30980.1 - 6.2e-22 77.3 0.0 1.2e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30980.1 - 1.2e-12 47.4 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME30980.1 - 2.6e-08 33.5 2.1 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EME30980.1 - 9.7e-06 25.3 0.0 0.052 13.4 0.0 2.7 3 0 0 3 3 3 2 RNA binding motif SPOR PF05036.8 EME30980.1 - 0.0031 17.6 0.0 1.7 8.8 0.0 2.5 2 1 0 2 2 2 2 Sporulation related domain Calcipressin PF04847.7 EME30980.1 - 0.088 12.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Calcipressin RRM_1 PF00076.17 EME30981.1 - 2.6e-31 107.0 0.0 1.6e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME30981.1 - 6.4e-22 77.3 0.0 1.2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME30981.1 - 1.2e-12 47.4 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME30981.1 - 2.6e-08 33.4 2.1 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EME30981.1 - 1.4e-05 24.9 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif SPOR PF05036.8 EME30981.1 - 0.0032 17.5 0.0 1.7 8.8 0.0 2.4 2 1 0 2 2 2 2 Sporulation related domain Calcipressin PF04847.7 EME30981.1 - 0.094 12.2 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Calcipressin tRNA_bind PF01588.15 EME30982.1 - 3.5e-29 100.4 0.0 6.7e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 EME30982.1 - 2.7e-06 27.2 0.8 8.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME30982.1 - 1.7e-05 25.2 1.0 7.3e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME30982.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PolyA_pol PF01743.15 EME30982.1 - 0.0017 18.5 0.3 0.0033 17.6 0.2 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain LMWPc PF01451.16 EME30983.1 - 1.7e-33 115.8 0.0 2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Brix PF04427.13 EME30984.1 - 5.4e-42 143.6 0.1 6.6e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 Brix domain FAD_binding_3 PF01494.14 EME30985.1 - 1.8e-10 40.3 0.2 7.7e-05 21.8 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 EME30985.1 - 2e-06 26.9 0.0 4.2e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME30985.1 - 0.0097 14.8 0.3 0.03 13.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EME30985.1 - 0.019 13.6 0.3 0.026 13.1 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EME30985.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME30985.1 - 0.035 12.9 0.5 0.055 12.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EME30985.1 - 0.041 13.9 0.5 0.084 12.9 0.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME30985.1 - 0.05 13.4 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EME30986.1 - 4.2e-19 68.3 0.1 6.9e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME30986.1 - 1.8e-08 34.1 2.7 3.6e-07 29.9 0.2 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME30986.1 - 2.9e-08 34.6 0.0 6.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EME30986.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.20 EME30987.1 - 8.1e-73 244.7 0.0 1.2e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME30987.1 - 2.7e-50 170.8 0.0 4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME30987.1 - 9.2e-06 24.8 0.0 0.00081 18.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF1241 PF06840.6 EME30987.1 - 0.00053 19.2 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) APH PF01636.18 EME30987.1 - 0.00056 19.7 0.0 0.18 11.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME30987.1 - 0.0039 16.2 0.0 0.017 14.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 EME30988.1 - 2.4e-44 150.8 0.0 7.2e-44 149.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SPRY PF00622.23 EME30988.1 - 6.8e-28 97.2 0.3 1.4e-27 96.2 0.2 1.6 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 EME30988.1 - 5.3e-23 80.6 0.0 1.3e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EME30988.1 - 0.0021 16.5 0.0 0.083 11.2 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) AAA_21 PF13304.1 EME30988.1 - 0.06 13.2 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME30988.1 - 0.14 12.3 1.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain PI3_PI4_kinase PF00454.22 EME30989.1 - 7.6e-28 97.5 0.1 1.5e-26 93.3 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 EME30989.1 - 0.024 13.6 0.7 0.04 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) ScpA_ScpB PF02616.9 EME30989.1 - 2 7.9 6.2 2 7.9 1.6 2.3 2 0 0 2 2 2 0 ScpA/B protein DUF1295 PF06966.7 EME30990.1 - 2.7e-59 200.3 5.5 3.1e-59 200.1 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EME30990.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EME30990.1 - 0.0028 17.8 0.5 0.01 16.0 0.3 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EME30990.1 - 0.73 9.5 11.1 0.021 14.6 2.9 2.1 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DNA_processg_A PF02481.10 EME30991.1 - 8.2e-05 21.5 0.1 0.00032 19.6 0.0 1.8 2 0 0 2 2 2 1 DNA recombination-mediator protein A MscL PF01741.13 EME30992.1 - 0.019 15.1 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF4381 PF14316.1 EME30992.1 - 0.23 11.5 1.3 0.68 10.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Rotamase_3 PF13616.1 EME30993.1 - 2.1e-22 79.5 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EME30993.1 - 2.8e-20 72.8 0.0 6.1e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rhodanese PF00581.15 EME30993.1 - 2.2e-11 44.1 0.0 1e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Rotamase_2 PF13145.1 EME30993.1 - 2.6e-05 24.8 0.0 0.00011 22.7 0.0 1.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain ABC1 PF03109.11 EME30994.1 - 3.5e-19 68.9 0.0 2.4e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 ABC1 family ITAM PF02189.10 EME30994.1 - 0.015 15.5 0.7 0.043 14.1 0.5 1.8 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Zn_ribbon_recom PF13408.1 EME30994.1 - 0.23 11.7 2.2 0.47 10.7 1.5 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Vps54 PF07928.7 EME30995.1 - 1.3e-28 99.7 4.7 1.3e-28 99.7 3.3 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EME30995.1 - 1.2e-12 47.4 7.2 1.2e-12 47.4 5.0 2.6 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EME30995.1 - 9.6e-06 25.2 4.1 9.6e-06 25.2 2.8 3.1 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain XhoI PF04555.8 EME30995.1 - 0.062 12.7 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease XhoI NPV_P10 PF05531.7 EME30995.1 - 0.1 12.8 3.2 1 9.6 0.2 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EME30995.1 - 0.74 9.6 5.3 0.43 10.3 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.1 EME30996.1 - 4.9e-13 48.6 4.2 1e-12 47.6 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME30996.1 - 2e-07 30.9 6.1 2.4e-07 30.6 2.2 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME30996.1 - 9.9e-07 28.3 1.1 9.9e-07 28.3 0.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME30996.1 - 2.1e-06 27.2 5.0 7.8e-06 25.4 3.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME30996.1 - 3.2e-06 26.7 3.2 1e-05 25.1 2.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME30996.1 - 4.4e-06 26.6 7.4 0.00011 22.1 4.9 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EME30996.1 - 0.00093 19.1 6.0 0.0017 18.2 3.4 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EME30996.1 - 0.0063 16.6 2.7 0.014 15.5 0.8 2.0 1 1 1 2 2 2 1 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EME30996.1 - 0.017 14.8 7.9 0.026 14.2 0.5 2.8 2 1 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EME30996.1 - 0.026 14.5 1.7 0.088 12.8 1.2 2.0 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 EME30996.1 - 0.075 13.0 4.1 0.039 13.9 1.2 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_4 PF15227.1 EME30996.1 - 0.35 10.7 8.0 0.15 11.9 0.9 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EME30996.1 - 1.7 8.5 7.6 1.4 8.8 2.4 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME30996.1 - 3.7 7.1 6.0 5.5 6.6 0.7 2.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SRR1 PF07985.7 EME30997.1 - 9e-15 54.3 0.2 2.4e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 SRR1 2-oxoacid_dh PF00198.18 EME30999.1 - 1.2e-87 292.9 0.1 1.6e-87 292.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME30999.1 - 1.7e-18 66.0 0.1 4.1e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EME30999.1 - 4.2e-12 45.5 0.0 1.2e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Joubert PF15392.1 EME30999.1 - 0.03 13.5 1.2 0.046 12.9 0.5 1.5 2 0 0 2 2 2 0 Joubert syndrome-associated Prefoldin_2 PF01920.15 EME31000.1 - 0.26 11.0 2.1 0.33 10.7 1.5 1.1 1 0 0 1 1 1 0 Prefoldin subunit Actin PF00022.14 EME31001.1 - 7.4e-158 525.0 0.0 8.4e-158 524.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EME31001.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_1_2 PF00155.16 EME31003.1 - 8.6e-53 179.5 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME31003.1 - 2.5e-08 33.0 0.0 6.7e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME31003.1 - 7.9e-05 21.8 0.1 0.00045 19.3 0.0 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME31003.1 - 8.4e-05 21.0 0.0 0.00013 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EME31003.1 - 0.0042 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EME31003.1 - 0.061 11.8 0.0 1.5 7.2 0.0 2.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Nramp PF01566.13 EME31004.1 - 2e-125 418.2 19.0 2e-125 418.2 13.2 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Voltage_CLC PF00654.15 EME31005.1 - 8.2e-74 248.7 20.7 8.2e-74 248.7 14.4 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EME31005.1 - 4.9e-13 48.6 0.1 8.2e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain zf-DHHC PF01529.15 EME31005.1 - 0.063 12.6 0.0 0.35 10.2 0.0 2.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase NUMOD3 PF07460.6 EME31006.1 - 2.2e-13 49.8 6.8 2.4e-07 30.5 3.8 3.6 1 1 2 3 3 3 3 NUMOD3 motif (2 copies) SpoU_methylase PF00588.14 EME31007.1 - 1.3e-29 102.8 0.0 1.7e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Antistasin PF02822.9 EME31007.1 - 0.49 10.7 3.6 3.5 8.0 0.9 2.6 3 0 0 3 3 3 0 Antistasin family SpoU_methylase PF00588.14 EME31008.1 - 1.3e-29 102.8 0.0 1.7e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Antistasin PF02822.9 EME31008.1 - 0.49 10.7 3.6 3.5 8.0 0.9 2.6 3 0 0 3 3 3 0 Antistasin family Cyt-b5 PF00173.23 EME31009.1 - 8.5e-27 92.7 0.1 1.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2077 PF09850.4 EME31009.1 - 0.081 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Cytochrom_C1 PF02167.10 EME31010.1 - 1.3e-84 283.2 0.0 1.6e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EME31010.1 - 6.5e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EME31010.1 - 0.0025 18.6 1.1 0.0098 16.7 0.3 2.2 2 1 0 2 2 2 1 Cytochrome c Cytochrom_C550 PF14495.1 EME31010.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain DUF3357 PF11837.3 EME31011.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) BAR PF03114.13 EME31012.1 - 5.9e-10 39.0 11.7 5.9e-10 39.0 8.1 1.6 1 1 0 1 1 1 1 BAR domain Xpo1 PF08389.7 EME31012.1 - 0.013 15.3 4.7 0.032 14.1 2.3 2.3 2 1 0 2 2 2 0 Exportin 1-like protein DUF947 PF06102.7 EME31012.1 - 0.041 13.7 24.1 0.25 11.1 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF947) DUF305 PF03713.8 EME31012.1 - 0.9 9.3 5.0 0.38 10.5 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF305) DUF4164 PF13747.1 EME31012.1 - 1.2 9.3 7.7 0.36 10.9 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) OSTMP1 PF09777.4 EME31012.1 - 1.8 7.6 12.2 0.27 10.3 4.0 2.1 1 1 2 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor AAA_11 PF13086.1 EME31012.1 - 3.6 7.0 17.0 0.34 10.4 6.2 2.5 1 1 1 2 2 2 0 AAA domain DXP_synthase_N PF13292.1 EME31012.1 - 3.8 6.3 9.0 0.3 10.0 1.9 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase AAA_23 PF13476.1 EME31012.1 - 4.4 7.5 15.0 0.28 11.4 6.2 1.8 2 0 0 2 2 2 0 AAA domain DUF4473 PF14747.1 EME31012.1 - 5.1 7.3 10.6 17 5.7 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4473) PI3_PI4_kinase PF00454.22 EME31013.1 - 2.5e-18 66.4 0.0 5.4e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Mito_carr PF00153.22 EME31014.1 - 1.5e-65 216.8 5.0 1.6e-24 85.4 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF565 PF04483.7 EME31014.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF565) Voltage_CLC PF00654.15 EME31016.1 - 5.8e-76 255.8 25.9 5.8e-76 255.8 18.0 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel NUDIX PF00293.23 EME31017.1 - 2.1e-14 53.3 0.0 3.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EME31017.1 - 4e-06 27.0 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EME31017.1 - 0.00015 21.2 3.3 0.00031 20.2 2.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain peroxidase PF00141.18 EME31018.1 - 3.9e-36 124.6 0.0 9.1e-36 123.4 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Herpes_capsid PF06112.6 EME31018.1 - 6.4 6.7 8.7 12 5.9 6.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein peroxidase PF00141.18 EME31019.1 - 5.3e-35 120.9 0.0 1.2e-34 119.8 0.0 1.4 1 1 0 1 1 1 1 Peroxidase WD40 PF00400.27 EME31022.1 - 2.4e-34 115.9 3.7 3.4e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat adh_short PF00106.20 EME31023.1 - 2.7e-21 76.2 0.1 1.5e-20 73.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME31023.1 - 2.2e-08 33.9 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME31023.1 - 8.1e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME31023.1 - 6e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME31023.1 - 0.00065 19.7 0.5 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EME31023.1 - 0.021 13.9 0.2 0.048 12.7 0.2 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EME31023.1 - 0.054 13.3 0.2 0.14 12.0 0.2 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EME31023.1 - 0.066 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nucleotid_trans PF03407.11 EME31024.1 - 2.4e-20 73.2 0.0 4.5e-20 72.3 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SMC_N PF02463.14 EME31026.1 - 1e-53 181.8 57.3 1e-52 178.5 39.7 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME31026.1 - 8.3e-17 61.2 1.6 7.4e-16 58.2 0.0 3.5 2 2 1 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME31026.1 - 7.7e-09 35.9 4.6 9.5e-06 25.7 0.3 4.2 4 2 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EME31026.1 - 1.4e-05 24.4 0.1 8.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Laminin_II PF06009.7 EME31026.1 - 0.0014 18.3 8.9 0.0014 18.3 6.1 8.0 2 2 4 7 7 7 3 Laminin Domain II APG6 PF04111.7 EME31026.1 - 0.0049 15.9 24.9 0.0049 15.9 17.3 7.2 2 2 5 8 8 8 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EME31026.1 - 0.0089 15.8 21.2 0.0089 15.8 14.7 7.8 2 2 4 7 7 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EME31026.1 - 0.019 13.4 113.9 0.009 14.5 21.1 6.0 3 2 2 5 5 5 0 AAA domain KH_5 PF13184.1 EME31026.1 - 0.098 12.4 4.1 0.2 11.4 0.5 3.4 3 0 0 3 3 3 0 NusA-like KH domain Tropomyosin_1 PF12718.2 EME31026.1 - 0.89 9.3 142.8 0.014 15.2 17.4 8.6 2 2 6 9 9 9 0 Tropomyosin like AAA_23 PF13476.1 EME31026.1 - 1.3 9.2 140.4 0.6 10.3 41.3 7.4 2 2 0 2 2 1 0 AAA domain SMC_N PF02463.14 EME31027.1 - 5.2e-55 186.0 53.0 4.8e-54 182.9 36.7 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME31027.1 - 3.4e-26 91.5 0.8 2.9e-25 88.5 0.0 3.0 2 1 1 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EME31027.1 - 7e-14 52.6 16.9 7e-14 52.6 11.7 7.3 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 EME31027.1 - 7.9e-09 35.8 4.6 9.6e-06 25.7 0.3 4.2 4 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 EME31027.1 - 1.5e-05 24.4 0.1 8.7e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Laminin_II PF06009.7 EME31027.1 - 0.0018 18.0 9.2 0.0018 18.0 6.4 8.0 2 2 4 7 7 7 2 Laminin Domain II APG6 PF04111.7 EME31027.1 - 0.0047 16.0 24.8 0.0047 16.0 17.2 7.2 2 2 7 9 9 9 3 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EME31027.1 - 0.0081 16.0 21.1 0.0081 16.0 14.6 7.9 2 2 4 7 7 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EME31027.1 - 0.022 13.2 114.0 0.0091 14.5 21.1 6.0 3 2 3 6 6 6 0 AAA domain KH_5 PF13184.1 EME31027.1 - 0.1 12.3 4.0 0.21 11.4 0.5 3.4 3 0 0 3 3 3 0 NusA-like KH domain Tropomyosin_1 PF12718.2 EME31027.1 - 0.56 10.0 142.2 0.027 14.3 17.4 8.6 2 2 5 8 8 8 0 Tropomyosin like Reo_sigmaC PF04582.7 EME31027.1 - 3 6.9 31.5 0.043 12.9 3.7 5.1 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Ribosomal_L10 PF00466.15 EME31028.1 - 1.9e-23 82.2 0.1 4.5e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EME31028.1 - 9.7e-10 38.7 0.9 3.5e-09 36.9 0.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein NSs PF11073.3 EME31028.1 - 0.024 13.8 0.0 0.056 12.6 0.0 1.6 1 1 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Synuclein PF01387.12 EME31028.1 - 0.081 12.8 1.7 0.19 11.6 0.3 2.0 2 0 0 2 2 2 0 Synuclein Myc_N PF01056.13 EME31028.1 - 0.1 11.7 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ras PF00071.17 EME31029.1 - 5.6e-32 110.3 0.1 7.1e-32 110.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME31029.1 - 2.1e-19 70.1 0.0 3.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME31029.1 - 1.6e-07 30.7 0.1 1.7e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME31029.1 - 3.3e-06 26.3 0.1 3.9e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME31029.1 - 0.002 17.5 0.0 0.004 16.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME31029.1 - 0.0065 16.4 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase LytTR PF04397.10 EME31030.1 - 0.087 12.9 1.2 0.1 12.6 0.8 1.2 1 0 0 1 1 1 0 LytTr DNA-binding domain zf-RING_2 PF13639.1 EME31031.1 - 4.1e-13 48.9 5.0 6.4e-13 48.3 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME31031.1 - 6.2e-09 35.3 2.3 9.5e-09 34.7 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME31031.1 - 1.3e-08 34.8 4.5 3.5e-08 33.4 3.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME31031.1 - 2.9e-08 33.5 5.0 4.6e-08 32.9 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31031.1 - 1.5e-07 30.9 2.7 2.1e-07 30.5 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31031.1 - 6.5e-07 28.9 2.3 9.7e-07 28.4 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME31031.1 - 0.00042 20.0 2.8 0.001 18.8 1.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EME31031.1 - 0.0087 15.5 3.2 0.024 14.1 2.2 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EME31031.1 - 0.0092 15.8 1.2 0.021 14.6 0.8 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EME31031.1 - 0.018 14.6 1.1 0.032 13.8 0.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FdhE PF04216.7 EME31031.1 - 0.072 12.7 2.3 0.11 12.1 1.6 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation FANCL_C PF11793.3 EME31031.1 - 0.12 12.3 3.2 3.2 7.7 2.2 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EME31031.1 - 0.2 11.4 2.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EME31031.1 - 0.45 10.2 2.4 0.76 9.5 0.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EME31031.1 - 0.45 10.6 2.9 1.1 9.3 2.0 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.24 EME31031.1 - 0.51 10.0 2.9 1.6 8.4 2.1 1.8 1 1 1 2 2 2 0 PHD-finger Mpv17_PMP22 PF04117.7 EME31032.1 - 6.8e-22 76.8 1.0 6.8e-22 76.8 0.7 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family Sugar_tr PF00083.19 EME31033.1 - 4.7e-24 84.7 32.5 1.2e-22 80.1 22.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31033.1 - 3.1e-13 49.1 57.4 3.3e-09 35.9 23.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME31033.1 - 0.00021 19.8 12.0 0.00021 19.8 8.3 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF4590 PF15257.1 EME31033.1 - 0.075 12.8 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) PCI PF01399.22 EME31034.1 - 1.6e-19 70.1 1.9 2.8e-19 69.3 0.2 2.2 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 EME31034.1 - 0.93 10.2 10.9 4.8 7.9 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Zip PF02535.17 EME31035.1 - 1.8e-18 66.6 13.1 4.6e-15 55.4 1.0 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter CBS PF00571.23 EME31036.1 - 5.5e-34 115.6 1.1 2.7e-11 43.0 0.0 4.3 4 0 0 4 4 4 4 CBS domain Sds3 PF08598.6 EME31037.1 - 7.7e-05 22.3 9.3 7.7e-05 22.3 6.4 1.6 2 0 0 2 2 2 1 Sds3-like Oxidored_nitro PF00148.14 EME31037.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Sds3 PF08598.6 EME31038.1 - 0.0023 17.5 7.6 0.0023 17.5 5.3 1.6 2 0 0 2 2 2 1 Sds3-like Oxidored_nitro PF00148.14 EME31038.1 - 0.14 10.7 0.0 0.29 9.7 0.0 1.4 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ank_5 PF13857.1 EME31039.1 - 6.6e-25 86.5 0.0 5.7e-13 48.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EME31039.1 - 2.3e-19 68.1 0.0 1e-08 34.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EME31039.1 - 1e-17 64.2 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) ACBP PF00887.14 EME31039.1 - 7.7e-17 60.7 3.1 1.2e-16 60.1 2.2 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.1 EME31039.1 - 1.6e-16 60.3 0.0 6.4e-10 39.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME31039.1 - 1.2e-12 46.7 0.1 0.00019 21.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat YfmQ PF10787.4 EME31039.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Siva PF05458.7 EME31040.1 - 0.00064 19.3 17.0 0.001 18.6 11.8 1.3 1 0 0 1 1 1 1 Cd27 binding protein (Siva) EST1 PF10374.4 EME31040.1 - 0.08 12.9 0.3 0.16 12.0 0.2 1.7 1 1 0 1 1 1 0 Telomerase activating protein Est1 RPN7 PF10602.4 EME31041.1 - 1.7e-43 148.0 0.9 3.1e-43 147.1 0.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EME31041.1 - 1.7e-13 50.7 0.1 2.4e-12 47.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 EME31041.1 - 0.012 15.2 1.1 0.031 13.8 0.8 1.7 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_14 PF13428.1 EME31041.1 - 0.036 14.6 2.7 0.36 11.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PRP4 PF08799.6 EME31041.1 - 0.58 9.4 2.6 9.1 5.6 0.1 3.2 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like RNA_POL_M_15KD PF02150.11 EME31042.1 - 1.6e-07 30.8 7.8 9.2e-07 28.4 5.4 1.9 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EME31042.1 - 0.0054 16.5 0.5 0.0075 16.0 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Rpr2 PF04032.11 EME31042.1 - 0.0095 15.7 0.3 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain NinF PF05810.7 EME31042.1 - 0.052 13.3 1.2 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 NinF protein C1_1 PF00130.17 EME31042.1 - 0.095 12.4 0.4 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sigma70_r4_2 PF08281.7 EME31042.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 zf-ribbon_3 PF13248.1 EME31042.1 - 0.21 10.8 1.4 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EME31042.1 - 0.31 10.8 2.3 0.64 9.8 1.6 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 EME31042.1 - 0.51 10.3 3.0 23 5.0 0.5 2.9 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 Metallophos_2 PF12850.2 EME31043.1 - 6.3e-16 58.6 0.0 7.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EME31043.1 - 0.00012 21.5 0.0 0.081 12.3 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EME31043.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Metallophos_2 PF12850.2 EME31044.1 - 8.9e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EME31044.1 - 0.059 12.7 0.1 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Pro_dh PF01619.13 EME31045.1 - 5.5e-58 196.4 0.1 8.7e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Sel1 PF08238.7 EME31047.1 - 2.7e-39 132.7 38.9 4.2e-08 33.5 0.4 11.7 12 0 0 12 12 12 9 Sel1 repeat TPR_7 PF13176.1 EME31047.1 - 0.045 13.5 0.1 2.2 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME31047.1 - 0.19 12.0 2.3 81 3.7 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME31047.1 - 3.6 7.7 15.8 8.7 6.5 0.1 6.6 5 2 0 5 5 5 0 Tetratricopeptide repeat ThiC PF01964.13 EME31048.1 - 3.2e-196 651.8 0.0 3.8e-196 651.6 0.0 1.0 1 0 0 1 1 1 1 ThiC family ThiC-associated PF13667.1 EME31048.1 - 7.4e-09 35.0 0.0 1.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 ThiC-associated domain Mak10 PF04112.8 EME31049.1 - 0.045 12.9 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_8 PF00895.15 EME31049.1 - 0.06 13.5 0.3 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3357 PF11837.3 EME31049.1 - 0.068 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) UN_NPL4 PF11543.3 EME31049.1 - 0.11 12.8 0.3 0.31 11.3 0.0 1.8 2 1 0 2 2 2 0 Nuclear pore localisation protein NPL4 ESSS PF10183.4 EME31049.1 - 0.15 12.4 0.4 0.25 11.7 0.2 1.5 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) bZIP_2 PF07716.10 EME31050.1 - 0.00011 21.8 2.6 0.00011 21.8 1.8 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EME31050.1 - 0.00022 21.1 4.8 0.00055 19.8 3.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EME31050.1 - 0.13 12.6 4.3 0.25 11.6 3.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EME31051.1 - 1.7e-05 24.5 9.3 1.7e-05 24.5 6.4 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EME31051.1 - 5.2e-05 23.1 10.8 5.2e-05 23.1 7.5 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EME31051.1 - 0.16 12.2 4.7 0.24 11.7 3.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor LYTB PF02401.13 EME31052.1 - 2e-86 289.4 0.0 2.6e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 LytB protein BDM PF10684.4 EME31052.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein zf-C2HC_2 PF13913.1 EME31057.1 - 0.11 12.2 1.4 7.9 6.2 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4363 PF14276.1 EME31060.1 - 0.056 13.1 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Arch_ATPase PF01637.13 EME31061.1 - 0.0038 16.9 0.1 0.046 13.3 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase Aa_trans PF01490.13 EME31066.1 - 2.6e-36 124.9 38.4 3e-36 124.7 26.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME31066.1 - 1.7e-06 27.1 16.6 1.7e-06 27.1 11.5 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease PF00324.16 EME31066.1 - 0.15 10.3 39.6 0.041 12.2 21.2 2.4 2 1 0 2 2 2 0 Amino acid permease Aa_trans PF01490.13 EME31067.1 - 2.6e-36 124.9 38.4 3e-36 124.7 26.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME31067.1 - 1.7e-06 27.1 16.6 1.7e-06 27.1 11.5 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease PF00324.16 EME31067.1 - 0.15 10.3 39.6 0.041 12.2 21.2 2.4 2 1 0 2 2 2 0 Amino acid permease H_PPase PF03030.11 EME31068.1 - 7.7e-273 906.8 28.5 8.7e-273 906.6 19.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase PCMT PF01135.14 EME31069.1 - 1.8e-70 236.7 0.0 2.5e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EME31069.1 - 2.4e-05 24.8 0.0 4.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31069.1 - 0.0027 17.4 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EME31069.1 - 0.0048 16.0 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EME31069.1 - 0.0062 16.1 0.0 0.023 14.2 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME31069.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EME31069.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.12 EME31069.1 - 0.033 13.1 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Methyltransf_26 PF13659.1 EME31069.1 - 0.041 13.9 0.0 0.099 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF4427 PF14468.1 EME31069.1 - 0.055 13.1 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) Methyltransf_24 PF13578.1 EME31069.1 - 0.11 13.3 0.0 0.52 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EME31069.1 - 0.14 12.6 0.0 0.72 10.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EME31069.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain NAD_binding_2 PF03446.10 EME31070.1 - 2.1e-47 161.0 0.3 3e-47 160.4 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME31070.1 - 1.9e-31 108.6 0.3 3.4e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EME31070.1 - 3.3e-09 36.9 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EME31070.1 - 4.3e-08 33.4 0.0 9.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME31070.1 - 6.5e-06 25.4 0.0 1.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.12 EME31070.1 - 0.05 12.4 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydrogenase OCD_Mu_crystall PF02423.10 EME31070.1 - 0.086 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 6PGD PF00393.14 EME31071.1 - 2.4e-133 443.8 0.0 3.3e-133 443.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EME31071.1 - 1.8e-52 177.4 0.0 2.7e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EME31071.1 - 0.0036 17.3 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EME31071.1 - 0.039 13.1 0.1 0.088 11.9 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 EME31071.1 - 0.041 13.9 0.0 0.096 12.7 0.0 1.8 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Peptidase_S58 PF03576.9 EME31072.1 - 6.2e-64 216.2 2.5 7.4e-64 215.9 1.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 Tachystatin_A PF11406.3 EME31072.1 - 0.14 11.9 2.9 22 5.0 0.1 3.7 4 0 0 4 4 4 0 Antimicrobial peptide tachystatin A Peptidase_S58 PF03576.9 EME31073.1 - 6.2e-64 216.2 2.5 7.4e-64 215.9 1.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 Tachystatin_A PF11406.3 EME31073.1 - 0.14 11.9 2.9 22 5.0 0.1 3.7 4 0 0 4 4 4 0 Antimicrobial peptide tachystatin A YceG PF02618.11 EME31074.1 - 0.0065 15.5 0.2 0.0094 15.0 0.1 1.2 1 0 0 1 1 1 1 YceG-like family DDE_Tnp_1 PF01609.16 EME31074.1 - 0.057 12.9 0.2 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain Flavodoxin_4 PF12682.2 EME31074.1 - 0.12 11.6 0.1 0.26 10.6 0.1 1.7 1 1 0 1 1 1 0 Flavodoxin MRG PF05712.8 EME31075.1 - 6.1e-41 139.4 1.1 6.1e-41 139.4 0.8 1.9 1 1 1 2 2 2 1 MRG Tudor-knot PF11717.3 EME31075.1 - 6.3e-08 32.2 0.3 6.3e-08 32.2 0.2 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain MRG PF05712.8 EME31076.1 - 6.3e-41 139.4 1.0 6.3e-41 139.4 0.7 1.9 1 1 1 2 2 2 1 MRG Tudor-knot PF11717.3 EME31076.1 - 3.5e-07 29.8 1.7 5.2e-07 29.2 0.1 2.1 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain U3_assoc_6 PF08640.6 EME31077.1 - 1.6e-14 53.4 7.2 1.7e-13 50.0 5.6 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EME31077.1 - 0.067 13.8 1.9 68 4.5 0.1 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Phage_XkdX PF09693.5 EME31077.1 - 0.13 11.7 0.2 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Pkinase PF00069.20 EME31078.1 - 1.4e-68 230.9 0.1 1.5e-67 227.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31078.1 - 2.1e-34 118.7 0.0 3.5e-23 81.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME31078.1 - 9e-07 28.1 0.2 0.0011 17.9 0.2 3.0 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 EME31078.1 - 0.00012 21.9 0.1 0.00081 19.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EME31078.1 - 0.053 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 EME31079.1 - 7.9e-138 460.0 8.0 9.3e-138 459.8 5.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EME31079.1 - 0.016 15.2 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor RimK PF08443.6 EME31080.1 - 0.03 13.7 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dynein_light PF01221.13 EME31081.1 - 2.6e-33 113.8 1.4 3.2e-33 113.5 1.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EME31081.1 - 0.036 14.3 0.2 0.048 13.9 0.1 1.5 1 1 0 1 1 1 0 Ground-like domain Peptidase_M1 PF01433.15 EME31083.1 - 2.4e-142 474.6 0.0 3.2e-142 474.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EME31083.1 - 2.4e-62 211.0 0.0 4e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EME31083.1 - 1.3e-22 80.1 0.2 2.8e-22 79.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EME31083.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Proteasome PF00227.21 EME31084.1 - 7.2e-58 195.0 0.0 2.1e-57 193.4 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME31084.1 - 4.1e-15 54.7 0.0 6.7e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Bromodomain PF00439.20 EME31085.1 - 2e-17 62.8 0.0 4.5e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain H_PPase PF03030.11 EME31086.1 - 1.2e-257 856.6 28.1 1.4e-257 856.4 19.5 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF3671 PF12420.3 EME31086.1 - 3.2 7.7 8.4 5.1 7.1 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function XPG_N PF00752.12 EME31087.1 - 4.7e-29 100.6 0.0 2.5e-28 98.2 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EME31087.1 - 1.3e-27 95.6 0.0 5.9e-27 93.5 0.0 2.3 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EME31087.1 - 0.0066 16.6 1.3 0.16 12.2 0.0 3.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold SRP54 PF00448.17 EME31088.1 - 1.9e-75 252.6 0.1 3e-75 252.0 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EME31088.1 - 4e-26 91.2 0.4 4e-26 91.2 0.3 2.7 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 EME31088.1 - 1.5e-17 63.4 7.2 1.6e-17 63.3 3.4 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EME31088.1 - 3e-06 27.1 0.6 5.4e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME31088.1 - 6.6e-06 25.6 0.0 2.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EME31088.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EME31088.1 - 0.00077 18.9 0.1 0.0052 16.2 0.0 2.4 2 2 1 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EME31088.1 - 0.0032 17.6 0.2 0.026 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME31088.1 - 0.0043 16.1 0.0 0.0095 15.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.1 EME31088.1 - 0.013 15.4 0.0 7.4 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EME31088.1 - 0.038 13.5 0.1 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EME31088.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EME31088.1 - 0.079 12.9 0.0 0.27 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EME31088.1 - 0.086 11.9 0.2 0.3 10.1 0.1 1.9 1 1 0 1 1 1 0 KaiC NolV PF06635.7 EME31088.1 - 0.089 11.9 0.6 0.19 10.8 0.4 1.5 1 0 0 1 1 1 0 Nodulation protein NolV DUF373 PF04123.8 EME31088.1 - 0.1 11.5 0.4 0.16 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) PP2C PF00481.16 EME31089.1 - 5.5e-59 199.6 0.0 7.9e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME31089.1 - 3.5e-07 29.8 0.0 7.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C GlyL_C PF12524.3 EME31089.1 - 0.016 15.0 1.5 6.3 6.7 0.9 3.4 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal AMP-binding PF00501.23 EME31090.1 - 6.4e-90 301.5 0.0 8.1e-90 301.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME31090.1 - 4.5e-20 72.3 0.1 9.2e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSF_A PF03178.10 EME31091.1 - 9.9e-80 268.0 0.1 1.2e-77 261.2 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 EME31091.1 - 9.3e-79 264.8 0.0 1.5e-78 264.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EME31092.1 - 5.7e-83 278.6 0.0 7e-81 271.7 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 EME31092.1 - 8.8e-79 264.9 0.0 1.4e-78 264.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term dsrm PF00035.20 EME31093.1 - 4.7e-07 30.2 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Myb_DNA-binding PF00249.26 EME31094.1 - 6.2e-22 77.3 7.0 1.5e-07 31.3 0.3 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME31094.1 - 8e-22 77.1 3.1 7.4e-14 51.5 0.1 4.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain MazG PF03819.12 EME31094.1 - 0.05 13.5 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain DUF362 PF04015.7 EME31094.1 - 0.086 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Myb_DNA-bind_5 PF13873.1 EME31094.1 - 0.1 12.5 8.2 1.3 8.9 0.1 4.5 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain RFC1 PF08519.7 EME31095.1 - 2.4e-47 160.5 0.0 8.2e-47 158.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EME31095.1 - 1.2e-11 44.5 0.2 4.2e-10 39.6 0.0 2.9 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EME31095.1 - 1.5e-11 44.6 0.0 4.5e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EME31095.1 - 1.6e-09 37.0 0.2 5.7e-06 25.2 0.0 2.8 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EME31095.1 - 0.0001 21.1 1.5 0.0026 16.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EME31095.1 - 0.00022 20.3 0.0 0.00047 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EME31095.1 - 0.00029 20.0 2.1 0.00086 18.4 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EME31095.1 - 0.00039 20.5 0.1 0.012 15.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME31095.1 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EME31095.1 - 0.0014 19.3 0.1 0.006 17.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 EME31095.1 - 0.0015 18.5 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain NTPase_1 PF03266.10 EME31095.1 - 0.0021 17.8 0.6 0.26 10.9 0.0 2.7 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.1 EME31095.1 - 0.0022 18.2 0.1 0.042 14.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EME31095.1 - 0.0033 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pox_LP_H2 PF03356.10 EME31095.1 - 0.0044 16.7 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral late protein H2 AAA_16 PF13191.1 EME31095.1 - 0.0055 16.7 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.24 EME31095.1 - 0.0058 16.1 0.5 1.9 7.9 0.0 2.7 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.9 EME31095.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME31095.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.2 EME31095.1 - 0.03 14.1 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 twin BRCT domain AAA_19 PF13245.1 EME31095.1 - 0.084 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain GEMIN8 PF15348.1 EME31096.1 - 0.0056 16.7 0.3 0.093 12.7 0.0 2.1 2 0 0 2 2 2 1 Gemini of Cajal bodies-associated protein 8 ABC2_membrane PF01061.19 EME31097.1 - 1.3e-41 142.0 19.7 1.8e-41 141.6 13.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME31097.1 - 4.5e-30 104.7 1.4 5.8e-30 104.3 0.2 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EME31097.1 - 6.1e-10 39.5 2.8 4e-07 30.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EME31097.1 - 9.6e-09 34.7 6.3 1.6e-08 33.9 4.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EME31097.1 - 3.4e-05 23.3 0.0 0.00015 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME31097.1 - 5.5e-05 23.2 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EME31097.1 - 0.00016 21.0 0.6 0.0003 20.0 0.4 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EME31097.1 - 0.00035 19.8 0.1 0.00058 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EME31097.1 - 0.0039 16.3 1.0 0.7 8.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EME31097.1 - 0.0057 16.5 0.1 0.021 14.7 0.1 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EME31097.1 - 0.0081 16.9 0.0 0.021 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME31097.1 - 0.015 14.2 0.1 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EME31097.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EME31097.1 - 0.021 14.8 0.1 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME31097.1 - 0.026 14.6 0.7 0.25 11.5 0.2 2.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EME31097.1 - 0.035 13.3 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EME31097.1 - 0.038 13.5 0.2 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EME31097.1 - 0.054 12.3 0.1 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EME31097.1 - 0.07 12.8 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EME31097.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EME31097.1 - 0.077 12.5 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME31097.1 - 0.08 12.3 0.9 0.17 11.3 0.6 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EME31097.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EME31097.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EME31097.1 - 0.13 11.6 0.2 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EME31097.1 - 0.87 9.8 5.2 2.5 8.4 3.3 2.0 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EME31097.1 - 0.91 8.0 3.0 3.9 5.9 0.3 2.5 2 1 1 3 3 3 0 Predicted ATPase of the ABC class ABC2_membrane PF01061.19 EME31098.1 - 1.3e-41 142.0 19.7 1.8e-41 141.6 13.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME31098.1 - 4.8e-30 104.6 1.4 6e-30 104.3 0.2 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EME31098.1 - 6.9e-10 39.3 2.9 4.2e-07 30.2 0.2 3.2 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EME31098.1 - 5.7e-09 35.4 7.3 9.7e-09 34.7 5.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EME31098.1 - 3.6e-05 23.2 0.0 0.00016 21.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME31098.1 - 5.8e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EME31098.1 - 0.00016 20.9 0.6 0.00032 20.0 0.4 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EME31098.1 - 0.00036 19.7 0.1 0.00059 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EME31098.1 - 0.0043 16.1 1.1 0.73 8.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EME31098.1 - 0.006 16.4 0.1 0.021 14.7 0.1 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EME31098.1 - 0.0084 16.9 0.0 0.021 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME31098.1 - 0.015 14.1 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EME31098.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EME31098.1 - 0.021 14.7 0.1 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME31098.1 - 0.029 14.5 0.7 0.27 11.4 0.3 2.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EME31098.1 - 0.036 13.3 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EME31098.1 - 0.039 13.4 0.2 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EME31098.1 - 0.057 12.3 0.1 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EME31098.1 - 0.073 12.7 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EME31098.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EME31098.1 - 0.079 12.5 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME31098.1 - 0.082 12.3 0.9 0.17 11.2 0.6 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EME31098.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EME31098.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EME31098.1 - 0.13 11.6 0.2 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EME31098.1 - 1.5 9.0 5.9 5.2 7.3 4.1 2.0 1 1 0 1 1 1 0 AAA domain Steroid_dh PF02544.11 EME31099.1 - 1.1e-10 41.4 3.8 2.8e-10 40.1 2.6 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Mito_carr PF00153.22 EME31101.1 - 3.5e-65 215.7 4.9 1.6e-23 82.2 0.1 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein V4R PF02830.13 EME31101.1 - 0.19 11.6 0.1 14 5.6 0.1 2.3 2 0 0 2 2 2 0 V4R domain Mito_carr PF00153.22 EME31102.1 - 3.1e-68 225.5 4.6 1.4e-23 82.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_TL5_C PF14693.1 EME31103.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Aminotran_1_2 PF00155.16 EME31105.1 - 1.5e-59 201.8 0.0 1.9e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME31105.1 - 0.0051 15.9 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase F-box-like PF12937.2 EME31106.1 - 1e-16 60.3 0.7 2.9e-16 58.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME31106.1 - 1.7e-12 46.6 0.4 1.7e-12 46.6 0.3 2.1 2 0 0 2 2 2 1 F-box domain SPOC PF07744.8 EME31106.1 - 0.025 15.0 0.0 0.075 13.5 0.0 1.8 2 0 0 2 2 2 0 SPOC domain PRANC PF09372.5 EME31106.1 - 0.076 12.9 0.4 0.4 10.6 0.0 2.1 1 1 1 2 2 2 0 PRANC domain Iso_dh PF00180.15 EME31107.1 - 1e-74 251.6 0.0 1.2e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F1F0-ATPsyn_F PF10791.4 EME31107.1 - 0.03 14.5 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Metallophos_2 PF12850.2 EME31108.1 - 1.2e-09 38.2 0.0 4.3e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.14 EME31108.1 - 5.7e-09 35.5 8.1 4.9e-08 32.4 5.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME31108.1 - 1.3e-08 35.4 3.5 1.3e-08 35.4 2.4 5.2 2 2 1 3 3 3 2 AAA domain Metallophos PF00149.23 EME31108.1 - 8.1e-07 28.6 0.4 2.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SbcCD_C PF13558.1 EME31108.1 - 2e-06 27.6 0.0 8e-06 25.6 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EME31108.1 - 0.0098 15.8 5.2 0.012 15.5 0.5 3.3 3 1 0 3 3 3 1 AAA domain Cyt-b5 PF00173.23 EME31109.1 - 1.3e-25 88.9 0.0 1.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyridoxal_deC PF00282.14 EME31110.1 - 5.3e-86 288.3 0.0 7.2e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.14 EME31111.1 - 6.4e-86 288.1 0.0 8.8e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DEAD PF00270.24 EME31112.1 - 1.6e-39 135.0 0.0 6.6e-39 133.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31112.1 - 2.1e-20 72.3 0.0 4.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME31112.1 - 0.00074 19.3 0.0 0.0027 17.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DBP10CT PF08147.7 EME31112.1 - 0.0016 18.1 3.9 0.0043 16.8 2.7 1.8 1 1 0 1 1 1 1 DBP10CT (NUC160) domain AAA_22 PF13401.1 EME31112.1 - 0.23 11.5 1.2 2.8 8.0 0.1 3.1 3 1 0 3 3 3 0 AAA domain HSP70 PF00012.15 EME31113.1 - 5.8e-281 932.7 9.5 6.6e-281 932.5 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME31113.1 - 9.6e-18 63.8 3.6 3.3e-17 62.0 0.0 2.7 3 0 0 3 3 3 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EME31113.1 - 0.00063 18.9 1.6 0.047 12.7 0.0 3.1 2 2 0 2 2 2 1 Hydantoinase/oxoprolinase DUF3153 PF11353.3 EME31113.1 - 0.042 13.2 0.2 0.19 11.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) Caudo_TAP PF02413.12 EME31113.1 - 0.089 12.9 6.3 0.11 12.6 2.8 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Inositol_P PF00459.20 EME31114.1 - 2.3e-49 168.1 0.0 3.8e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.15 EME31115.1 - 2.6e-63 214.4 0.0 3.5e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EME31115.1 - 2.8e-32 111.2 0.5 5.8e-32 110.2 0.3 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EME31115.1 - 5.8e-08 32.8 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Rpn3_C PF08375.6 EME31116.1 - 4.3e-22 78.2 4.9 1.2e-21 76.8 3.4 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EME31116.1 - 7.4e-21 74.4 0.3 5.7e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EME31116.1 - 0.00043 19.9 6.5 0.0043 16.8 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EME31116.1 - 0.0047 16.6 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_1 PF00515.23 EME31116.1 - 0.011 15.2 0.9 0.34 10.5 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME31116.1 - 0.033 13.9 0.3 2.2 8.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME31116.1 - 2.1 9.2 11.2 2.7 8.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Not3 PF04065.10 EME31117.1 - 1.1e-76 257.1 24.7 2.4e-76 256.0 17.1 1.6 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EME31117.1 - 7.8e-45 152.0 3.3 3.9e-44 149.7 2.3 2.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF4407 PF14362.1 EME31117.1 - 1.6 7.6 4.1 3.2 6.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Angiomotin_C PF12240.3 EME31118.1 - 0.026 14.0 0.3 0.028 13.9 0.2 1.0 1 0 0 1 1 1 0 Angiomotin C terminal NTR2 PF15458.1 EME31118.1 - 0.051 12.7 0.3 0.058 12.6 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 SBP_bac_7 PF03480.8 EME31118.1 - 0.062 12.3 0.1 0.065 12.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Angiomotin_C PF12240.3 EME31119.1 - 0.026 14.0 0.3 0.028 13.9 0.2 1.0 1 0 0 1 1 1 0 Angiomotin C terminal NTR2 PF15458.1 EME31119.1 - 0.051 12.7 0.3 0.058 12.6 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 SBP_bac_7 PF03480.8 EME31119.1 - 0.062 12.3 0.1 0.065 12.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Telomerase_RBD PF12009.3 EME31121.1 - 9.5e-26 90.3 5.0 9.5e-26 90.3 3.5 3.0 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EME31121.1 - 4.8e-09 35.8 1.3 2.9e-08 33.3 0.2 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.3 EME31122.1 - 1e-25 90.2 5.0 1e-25 90.2 3.5 3.0 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EME31122.1 - 4.9e-09 35.8 1.2 3e-08 33.3 0.1 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CpcD PF01383.16 EME31123.1 - 2.2e-14 53.3 0.0 3.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 CpcD/allophycocyanin linker domain NifU PF01106.12 EME31124.1 - 9.7e-25 86.1 0.2 1.2e-18 66.6 0.1 3.0 2 1 0 2 2 2 2 NifU-like domain eIF-3_zeta PF05091.7 EME31125.1 - 2.8e-173 577.2 0.0 3.3e-173 577.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DEAD PF00270.24 EME31126.1 - 2.3e-39 134.5 0.2 8.4e-39 132.7 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31126.1 - 1.1e-22 79.6 0.0 3e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME31126.1 - 0.0036 17.4 0.0 0.019 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EME31126.1 - 0.033 13.2 0.0 0.087 11.8 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EME31126.1 - 0.07 12.9 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Y_phosphatase PF00102.22 EME31127.1 - 5.1e-06 26.0 0.0 1.6e-05 24.3 0.0 1.6 1 1 1 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EME31127.1 - 9.1e-05 22.0 0.0 0.00044 19.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain NDK PF00334.14 EME31128.1 - 2e-57 192.7 0.0 2.3e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MGAT2 PF05060.9 EME31129.1 - 1.2e-19 70.4 0.3 1.6e-12 47.0 0.1 2.1 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.10 EME31129.1 - 1.3e-09 37.1 0.9 1.8e-09 36.6 0.6 1.3 1 1 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 EME31130.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME31130.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Put_DNA-bind_N PF06971.8 EME31133.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Clr2 PF10383.4 EME31133.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 2OG-FeII_Oxy_3 PF13640.1 EME31134.1 - 8.3e-16 58.3 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EME31134.1 - 0.00011 21.7 0.7 0.00028 20.4 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Epimerase PF01370.16 EME31135.1 - 3.1e-15 56.2 0.0 5.4e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME31135.1 - 6.2e-11 41.7 0.0 1.1e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EME31135.1 - 7.5e-05 21.7 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EME31135.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EME31135.1 - 0.0038 15.9 0.0 0.0094 14.6 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME31136.1 - 5.9e-57 192.8 0.0 7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME31136.1 - 1.2e-18 66.7 0.0 1.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME31136.1 - 3.2e-16 59.0 0.0 1.1e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EME31136.1 - 7.3e-16 57.8 0.0 2.3e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EME31136.1 - 1.8e-14 53.3 0.0 5.2e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME31136.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME31136.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME31136.1 - 0.082 12.9 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Glycos_transf_2 PF00535.21 EME31139.1 - 1.7e-07 31.0 0.3 3.4e-07 30.1 0.2 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 TPR_11 PF13414.1 EME31140.1 - 1e-20 73.1 8.4 1e-08 34.6 0.2 3.6 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EME31140.1 - 1.3e-15 55.9 5.7 0.0089 15.8 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME31140.1 - 9.5e-14 50.3 8.3 1.7e-06 27.3 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EME31140.1 - 3.3e-13 48.7 1.2 0.0029 17.6 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME31140.1 - 1.5e-11 44.6 1.1 9e-07 29.4 0.1 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME31140.1 - 6.3e-09 35.6 5.5 6.7e-05 22.7 0.3 4.3 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME31140.1 - 2.8e-08 33.6 2.9 0.13 12.9 0.1 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME31140.1 - 4.1e-08 32.4 5.7 0.00048 19.7 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME31140.1 - 4.9e-08 32.1 5.7 0.11 12.2 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME31140.1 - 1.9e-07 31.2 5.2 0.0018 18.6 0.8 3.7 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME31140.1 - 2.6e-05 24.3 8.2 2.3 8.8 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME31140.1 - 6.6e-05 22.6 0.2 0.0029 17.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EME31140.1 - 0.00077 18.6 0.5 0.01 15.0 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_15 PF13429.1 EME31140.1 - 0.0027 16.8 2.1 0.019 14.0 1.3 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.1 EME31140.1 - 0.0038 16.9 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NARP1 PF12569.3 EME31140.1 - 0.025 13.3 1.8 0.69 8.5 0.1 2.8 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 Apc5 PF12862.2 EME31140.1 - 0.038 13.8 0.2 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Ribosomal_S13 PF00416.17 EME31141.1 - 5.4e-40 136.1 1.9 6.5e-40 135.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EME31141.1 - 0.069 11.6 0.0 0.074 11.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SAC3_GANP PF03399.11 EME31142.1 - 1.2e-47 162.1 4.3 1.2e-47 162.1 3.0 1.9 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EME31142.1 - 6.8e-06 25.9 0.0 2.1e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RRM_1 PF00076.17 EME31142.1 - 0.0048 16.5 0.1 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31142.1 - 0.019 14.9 0.0 0.069 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP59_mtransfer PF11735.3 EME31143.1 - 9.2e-36 123.2 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FolB PF02152.13 EME31144.1 - 3.3e-27 94.8 0.1 5.2e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Dihydroneopterin aldolase PA14 PF07691.7 EME31144.1 - 0.074 12.7 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 PA14 domain Csm1 PF12539.3 EME31145.1 - 1.3e-07 31.9 1.0 3.2e-07 30.7 0.3 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Tombus_P33 PF08500.5 EME31145.1 - 0.083 12.6 0.7 0.2 11.3 0.0 1.9 2 1 0 2 2 2 0 Tombusvirus p33 IncA PF04156.9 EME31145.1 - 0.72 9.4 18.7 1.9 8.0 13.0 1.9 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EME31145.1 - 10 5.7 15.3 1.2 8.6 2.4 2.8 2 1 1 3 3 3 0 Septum formation initiator Hint PF01079.15 EME31146.1 - 6.4e-37 126.8 0.2 8.6e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Hint module Vint PF14623.1 EME31146.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Hint-domain EVE PF01878.13 EME31146.1 - 0.14 12.1 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 EVE domain Rhomboid PF01694.17 EME31147.1 - 3.6e-18 65.9 17.6 6.2e-18 65.2 12.2 1.3 1 0 0 1 1 1 1 Rhomboid family Kelch_5 PF13854.1 EME31147.1 - 0.023 14.6 0.5 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 EME31147.1 - 0.023 14.2 0.1 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Kelch motif ApbA_C PF08546.6 EME31148.1 - 1.7e-31 108.7 0.1 3.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME31148.1 - 4.9e-20 71.4 0.1 8.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EME31148.1 - 0.052 13.2 0.2 0.5 10.0 0.1 2.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA_C PF08546.6 EME31149.1 - 1.7e-31 108.7 0.1 3.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME31149.1 - 4.9e-20 71.4 0.1 8.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EME31149.1 - 0.052 13.2 0.2 0.5 10.0 0.1 2.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1664 PF07889.7 EME31150.1 - 0.0041 16.9 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 EME31150.1 - 0.025 13.9 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region PhaP_Bmeg PF09602.5 EME31150.1 - 0.025 14.3 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Utp21 PF04192.7 EME31150.1 - 0.042 12.9 0.1 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain DUF1108 PF06531.6 EME31150.1 - 0.06 13.5 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) SDP_N PF12278.3 EME31150.1 - 0.081 12.5 0.2 0.092 12.3 0.1 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Mit_KHE1 PF10173.4 EME31150.1 - 0.14 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SPX PF03105.14 EME31151.1 - 7.6e-28 98.0 17.2 7.6e-28 98.0 11.9 1.4 2 0 0 2 2 2 1 SPX domain zf-C3HC4_4 PF15227.1 EME31151.1 - 2.8e-09 36.6 10.9 7.3e-09 35.3 7.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EME31151.1 - 1.9e-08 34.1 10.3 3.8e-08 33.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME31151.1 - 5.7e-08 32.2 7.9 1.2e-07 31.2 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31151.1 - 8.4e-08 31.7 6.7 1.6e-07 30.8 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME31151.1 - 1.8e-07 30.8 10.5 3.2e-07 30.0 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME31151.1 - 3.6e-07 29.8 9.4 6.8e-07 28.9 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME31151.1 - 7.9e-06 25.4 5.8 4.1e-05 23.2 2.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EME31151.1 - 0.0039 16.9 3.5 0.0077 15.9 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EME31151.1 - 0.0052 16.3 8.1 0.028 13.9 5.9 2.1 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.10 EME31151.1 - 0.013 15.4 0.0 0.051 13.5 0.0 2.1 1 0 0 1 1 1 0 U-box domain Elf1 PF05129.8 EME31151.1 - 0.1 12.2 2.6 0.43 10.3 0.2 3.0 4 0 0 4 4 3 0 Transcription elongation factor Elf1 like zf-rbx1 PF12678.2 EME31151.1 - 0.81 9.8 6.1 2.4 8.3 4.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger MMR_HSR1 PF01926.18 EME31152.1 - 3.5e-21 75.3 0.1 9.3e-21 73.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 EME31152.1 - 3.7e-14 52.6 0.0 8.5e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal Dynamin_N PF00350.18 EME31152.1 - 1.4e-06 28.1 0.2 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EME31152.1 - 5.3e-06 25.9 0.0 0.0038 16.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME31152.1 - 9e-05 21.7 1.7 0.00032 19.9 0.2 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.14 EME31152.1 - 0.0018 17.7 2.3 1.4 8.3 0.1 3.1 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EME31152.1 - 0.0043 16.5 0.3 0.94 8.9 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EME31152.1 - 0.011 15.1 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME31152.1 - 0.016 15.5 0.0 0.072 13.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EME31152.1 - 0.018 14.7 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EME31152.1 - 0.024 15.1 0.1 0.24 11.9 0.1 2.4 1 1 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EME31152.1 - 0.045 14.0 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Arf PF00025.16 EME31152.1 - 0.045 12.9 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 EME31152.1 - 0.053 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PEN-2 PF10251.4 EME31153.1 - 2.6e-05 24.3 0.6 3.3e-05 24.0 0.4 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Abhydrolase_6 PF12697.2 EME31154.1 - 1.8e-27 96.7 0.0 2.2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME31154.1 - 3e-19 69.5 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME31154.1 - 3.4e-12 46.3 0.0 8.1e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME31154.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EME31154.1 - 0.0038 17.4 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EME31154.1 - 0.0053 15.2 0.0 0.023 13.2 0.0 1.8 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.20 EME31154.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EME31154.1 - 0.05 12.4 0.0 0.18 10.6 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EME31154.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.6 EME31154.1 - 0.14 10.9 0.0 0.82 8.4 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase DnaJ_CXXCXGXG PF00684.14 EME31155.1 - 0.055 13.5 3.6 0.58 10.2 2.8 2.0 1 1 1 2 2 2 0 DnaJ central domain DUF4584 PF15223.1 EME31155.1 - 0.063 12.5 1.0 0.1 11.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) Vps52 PF04129.7 EME31156.1 - 9.6e-71 238.8 14.6 1.5e-70 238.1 10.1 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Nsp1_C PF05064.8 EME31156.1 - 0.025 14.1 0.8 0.025 14.1 0.6 2.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region Pkr1 PF08636.5 EME31157.1 - 0.00034 20.6 8.2 0.00043 20.2 5.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4181 PF13789.1 EME31157.1 - 0.054 13.4 1.0 0.061 13.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF4131 PF13567.1 EME31157.1 - 0.45 9.8 7.4 0.53 9.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4229 PF14012.1 EME31157.1 - 0.88 9.5 7.1 1.2 9.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) YfhO PF09586.5 EME31157.1 - 1.1 7.2 5.0 1.1 7.2 3.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3679 PF12438.3 EME31157.1 - 1.6 8.1 3.9 1.6 8.1 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3679) DUF1673 PF07895.6 EME31157.1 - 1.7 8.1 5.0 1.9 7.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) LPAM_1 PF08139.7 EME31157.1 - 1.7 8.9 5.7 1.1 9.6 0.2 2.5 2 1 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4199 PF13858.1 EME31157.1 - 1.9 8.3 6.6 2.2 8.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Sex_peptide PF08138.6 EME31157.1 - 8.2 6.3 9.5 15 5.5 0.1 2.1 1 1 1 2 2 2 0 Sex peptide (SP) family Raptor_N PF14538.1 EME31158.1 - 1.2e-51 174.6 0.0 2.3e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EME31158.1 - 3.5e-09 36.2 5.8 0.0013 18.4 0.1 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat HEAT_2 PF13646.1 EME31158.1 - 0.058 13.6 0.0 2.2 8.6 0.0 2.9 1 1 2 3 3 3 0 HEAT repeats Raptor_N PF14538.1 EME31159.1 - 1.2e-51 174.6 0.0 2.3e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EME31159.1 - 3.5e-09 36.2 5.8 0.0013 18.4 0.1 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat HEAT_2 PF13646.1 EME31159.1 - 0.058 13.6 0.0 2.2 8.6 0.0 2.9 1 1 2 3 3 3 0 HEAT repeats APG6 PF04111.7 EME31160.1 - 0.003 16.6 23.8 0.003 16.6 16.5 5.0 1 1 4 5 5 5 2 Autophagy protein Apg6 Filament PF00038.16 EME31160.1 - 0.016 14.7 72.4 0.033 13.6 27.2 2.8 1 1 1 2 2 2 0 Intermediate filament protein Methyltransf_5 PF01795.14 EME31161.1 - 1.8e-95 319.8 0.2 2.7e-95 319.2 0.2 1.3 1 0 0 1 1 1 1 MraW methylase family Methyltransf_15 PF09445.5 EME31161.1 - 0.0016 18.0 0.2 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 EME31161.1 - 0.024 15.4 0.0 0.071 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EME31161.1 - 0.029 14.3 0.0 0.083 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME31161.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22e PF01776.12 EME31162.1 - 1.1e-48 163.8 1.5 1.6e-48 163.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Ribosomal_L22e PF01776.12 EME31163.1 - 8.2e-49 164.2 1.5 1.1e-48 163.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.3 EME31163.1 - 0.11 12.7 0.8 0.25 11.6 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2660) Glyco_transf_90 PF05686.7 EME31165.1 - 3.2e-13 49.1 0.0 4.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EME31165.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Methyltransf_24 PF13578.1 EME31166.1 - 7e-16 58.9 0.3 9.1e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain TGS PF02824.16 EME31167.1 - 2.5e-19 68.8 0.1 5.5e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EME31167.1 - 3.1e-19 69.0 0.1 1.1e-18 67.2 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME31167.1 - 2.6e-11 43.0 0.0 6.9e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EME31167.1 - 5.9e-05 22.9 0.1 0.29 10.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EME31167.1 - 0.00016 22.1 0.0 0.001 19.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EME31167.1 - 0.00064 18.5 0.3 0.0027 16.5 0.0 1.9 2 0 0 2 2 2 1 ArgK protein SRPRB PF09439.5 EME31167.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EME31167.1 - 0.023 14.6 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EME31167.1 - 0.031 13.7 0.2 8.5 5.7 0.0 3.2 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EME31167.1 - 0.042 13.3 0.1 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EME31167.1 - 0.074 13.2 0.2 0.4 10.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EME31167.1 - 0.079 13.2 0.2 0.28 11.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EME31167.1 - 0.18 12.6 2.1 0.49 11.2 0.1 2.4 2 2 0 2 2 2 0 AAA domain Chorismate_bind PF00425.13 EME31169.1 - 6.2e-84 281.3 0.0 2.6e-83 279.3 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EME31169.1 - 9.5e-27 93.7 0.2 2.7e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Pkinase PF00069.20 EME31171.1 - 5.7e-45 153.4 0.0 9.5e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.16 EME31171.1 - 1.7e-39 135.7 0.0 2.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.12 EME31171.1 - 1.7e-37 128.9 0.0 3.3e-37 127.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31171.1 - 4.4e-06 25.8 0.0 6.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PP2C_2 PF13672.1 EME31171.1 - 7.8e-05 22.1 0.0 0.00029 20.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME31171.1 - 0.0053 16.4 0.0 0.13 11.9 0.0 2.5 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) APH PF01636.18 EME31171.1 - 0.12 12.0 0.2 1 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tra_M PF05261.6 EME31173.1 - 0.02 14.9 0.1 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 TraM protein, DNA-binding NADPH_Ox PF08414.5 EME31173.1 - 0.029 14.4 0.2 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Glyco_transf_90 PF05686.7 EME31174.1 - 1.1e-12 47.4 0.0 1.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 DUF3397 PF11877.3 EME31175.1 - 0.099 12.6 0.2 0.13 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3397) Raptor_N PF14538.1 EME31176.1 - 0.014 15.2 0.5 0.057 13.2 0.1 2.2 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Translin PF01997.11 EME31176.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.5 2 0 0 2 2 2 0 Translin family O-FucT PF10250.4 EME31177.1 - 0.00037 19.7 0.0 0.00075 18.6 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_7C PF02709.9 EME31178.1 - 0.00037 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Rif1_N PF12231.3 EME31179.1 - 0.025 13.5 0.5 0.026 13.5 0.4 1.0 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal AMP-binding_C PF13193.1 EME31180.1 - 6.5e-07 30.2 0.0 9.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cse1 PF08506.5 EME31181.1 - 0.024 13.2 0.1 0.035 12.6 0.1 1.1 1 0 0 1 1 1 0 Cse1 DUF3267 PF11667.3 EME31182.1 - 0.045 13.9 0.3 0.051 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) DUF2663 PF10864.3 EME31185.1 - 0.091 12.9 0.2 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2663 PF10864.3 EME31186.1 - 0.091 12.9 0.2 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) Amidohydro_4 PF13147.1 EME31187.1 - 1.9e-22 80.5 0.1 7.7e-22 78.6 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME31187.1 - 7.1e-17 62.0 0.1 5.9e-15 55.7 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EME31187.1 - 3.2e-10 39.8 0.0 0.0011 18.3 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 EME31187.1 - 6e-08 32.3 0.3 1.6e-07 31.0 0.2 1.7 1 1 0 1 1 1 1 Amidohydrolase CDC50 PF03381.10 EME31188.1 - 2.1e-79 266.5 0.0 3.1e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CART PF06373.6 EME31188.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) AAA PF00004.24 EME31189.1 - 2.6e-54 182.9 0.0 2e-45 154.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME31189.1 - 1.8e-05 23.8 0.0 4.7e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME31189.1 - 7.2e-05 22.9 0.0 0.0017 18.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME31189.1 - 7.3e-05 23.5 0.0 0.00036 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EME31189.1 - 0.00032 20.1 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EME31189.1 - 0.0007 19.6 0.6 0.013 15.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EME31189.1 - 0.0013 18.8 0.0 0.0048 17.0 0.0 2.1 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 EME31189.1 - 0.0018 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 EME31189.1 - 0.0024 17.6 0.1 0.021 14.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME31189.1 - 0.0026 17.6 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME31189.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EME31189.1 - 0.0037 17.1 0.0 0.008 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EME31189.1 - 0.01 14.9 0.0 0.03 13.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EME31189.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EME31189.1 - 0.014 14.8 0.2 0.28 10.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EME31189.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME31189.1 - 0.046 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EME31189.1 - 0.049 13.1 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EME31189.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EME31189.1 - 0.084 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EME31189.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EME31189.1 - 0.23 10.6 0.0 0.6 9.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein COX6B PF02297.12 EME31190.1 - 6.8e-18 64.4 8.6 8.1e-18 64.2 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EME31190.1 - 0.036 13.9 2.7 0.036 13.9 1.9 1.8 2 1 0 2 2 2 0 CHCH domain UPF0203 PF05254.7 EME31190.1 - 5.6 6.8 10.7 2.8 7.8 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) GDI PF00996.13 EME31191.1 - 2.4e-183 609.4 0.0 2.8e-183 609.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ZU5 PF00791.15 EME31191.1 - 0.092 12.4 0.5 0.42 10.3 0.1 2.0 1 1 1 2 2 2 0 ZU5 domain GDI PF00996.13 EME31192.1 - 6.6e-186 617.8 0.0 7.9e-186 617.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ZU5 PF00791.15 EME31192.1 - 0.095 12.3 0.5 0.43 10.2 0.1 2.1 1 1 1 2 2 2 0 ZU5 domain DAO PF01266.19 EME31193.1 - 1.4e-49 168.9 0.1 2e-49 168.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME31193.1 - 4e-07 29.2 5.1 0.0075 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EME31193.1 - 1.2e-06 27.8 0.3 4.3e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME31193.1 - 4.9e-05 22.5 0.5 0.036 13.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EME31193.1 - 0.012 15.2 0.3 0.049 13.2 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EME31193.1 - 0.015 15.2 0.5 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME31193.1 - 0.022 13.6 0.2 0.12 11.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EME31193.1 - 0.023 14.6 1.0 0.097 12.7 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME31193.1 - 0.15 12.4 0.6 0.4 11.1 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME31193.1 - 0.22 9.9 0.4 0.32 9.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.20 EME31194.1 - 2.2e-64 217.0 0.0 3.1e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31194.1 - 2.2e-34 118.7 0.0 3.3e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31194.1 - 1.6e-08 33.8 0.0 6.6e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FAM86 PF14904.1 EME31194.1 - 0.071 12.8 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function Acetyltransf_1 PF00583.19 EME31195.1 - 5.6e-13 48.7 0.1 9.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME31195.1 - 6e-10 38.7 0.0 9.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EME31195.1 - 3.5e-05 23.8 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME31195.1 - 6.4e-05 23.0 0.1 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME31195.1 - 0.03 14.1 0.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME31196.1 - 6.2e-13 48.5 0.1 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME31196.1 - 6.5e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EME31196.1 - 3.9e-05 23.7 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME31196.1 - 7.2e-05 22.8 0.1 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME31196.1 - 0.034 14.0 0.1 0.064 13.1 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CDC45 PF02724.9 EME31197.1 - 0.14 10.1 3.6 0.18 9.7 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S2 PF00318.15 EME31197.1 - 0.15 11.2 1.1 0.24 10.5 0.2 1.7 1 1 0 2 2 2 0 Ribosomal protein S2 Transket_pyr PF02779.19 EME31198.1 - 7.7e-48 162.3 0.0 1.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME31198.1 - 3.8e-38 130.2 0.0 1.3e-37 128.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain CN_hydrolase PF00795.17 EME31199.1 - 5.5e-32 110.6 0.0 9e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP-synt PF00231.14 EME31202.1 - 1.1e-96 323.5 0.0 1.3e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase DUF1884 PF08967.5 EME31202.1 - 0.0029 17.6 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1884) UPF0121 PF03661.8 EME31203.1 - 8e-09 35.0 12.5 1e-08 34.6 8.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) WD40 PF00400.27 EME31204.1 - 9e-55 180.7 21.4 1.8e-09 37.0 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME31204.1 - 1.1e-05 25.2 3.7 0.003 17.2 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EME31204.1 - 0.037 13.5 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EME31205.1 - 3.7e-58 191.4 21.4 1.8e-09 37.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME31205.1 - 1.4e-06 28.1 3.2 0.003 17.3 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EME31205.1 - 0.046 13.2 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.23 EME31206.1 - 2.7e-31 108.5 0.2 3.5e-30 104.9 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME31206.1 - 0.019 14.8 0.0 0.048 13.4 0.0 1.8 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain 2Fe-2S_thioredx PF01257.14 EME31207.1 - 9.1e-57 190.7 0.1 1.2e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin MBOAT_2 PF13813.1 EME31208.1 - 1.8e-11 43.9 2.3 1.8e-11 43.9 1.6 1.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 EME31208.1 - 1.3e-09 37.5 11.0 2e-09 37.0 7.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_S8 PF00082.17 EME31209.1 - 2.1e-27 95.9 0.0 4e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Selenoprotein_S PF06936.6 EME31210.1 - 0.0029 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Selenoprotein S (SelS) CDV3 PF15359.1 EME31210.1 - 0.008 16.2 1.3 0.015 15.3 0.9 1.5 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Ly49 PF08391.5 EME31210.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region PspB PF06667.7 EME31210.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage shock protein B DUF2570 PF10828.3 EME31210.1 - 1.2 8.7 4.5 0.51 9.9 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PQ-loop PF04193.9 EME31211.1 - 2.3e-16 59.0 11.6 5.9e-09 35.3 0.2 3.1 3 0 0 3 3 3 2 PQ loop repeat Sybindin PF04099.7 EME31212.1 - 1.5e-44 151.1 0.0 1.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EME31212.1 - 1.2e-09 38.1 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ACOX PF01756.14 EME31212.1 - 0.011 15.1 0.1 0.02 14.2 0.1 1.6 1 1 0 1 1 1 0 Acyl-CoA oxidase FKBP_C PF00254.23 EME31213.1 - 7.8e-15 54.6 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF775 PF05603.7 EME31214.1 - 3.9e-27 95.0 0.6 1.5e-26 93.1 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF775 PF05603.7 EME31215.1 - 3.4e-28 98.5 0.5 1.4e-27 96.5 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Coprogen_oxidas PF01218.13 EME31216.1 - 9.5e-11 40.7 0.0 9.9e-10 37.4 0.0 2.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase TetM_leader PF08076.6 EME31216.1 - 0.071 12.6 0.6 0.15 11.6 0.4 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide Coprogen_oxidas PF01218.13 EME31217.1 - 3.6e-10 38.9 0.0 3.5e-09 35.6 0.0 2.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase TetM_leader PF08076.6 EME31217.1 - 8.8 5.9 7.5 0.29 10.7 0.5 2.1 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide PCI PF01399.22 EME31218.1 - 4.4e-16 59.0 2.7 5.8e-16 58.7 0.1 2.5 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.1 EME31218.1 - 3.7e-07 29.9 1.3 0.00034 20.5 0.0 3.0 1 1 3 4 4 4 2 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EME31218.1 - 0.00034 20.3 0.1 0.00083 19.1 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EME31218.1 - 0.00097 18.7 1.0 4.9 7.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME31218.1 - 0.0058 16.3 1.9 4.1 7.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 EME31218.1 - 0.007 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EME31218.1 - 0.026 15.1 0.1 25 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME31218.1 - 0.075 12.9 0.0 7.8 6.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TC1 PF15063.1 EME31218.1 - 0.11 12.0 0.0 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Thyroid cancer protein 1 EamA PF00892.15 EME31219.1 - 0.15 12.0 2.4 0.26 11.3 1.6 1.4 1 0 0 1 1 1 0 EamA-like transporter family EamA PF00892.15 EME31220.1 - 0.16 12.0 2.4 0.29 11.1 1.6 1.4 1 0 0 1 1 1 0 EamA-like transporter family Alpha-amyl_C2 PF07821.7 EME31221.1 - 1.4e-15 56.8 0.6 2.5e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.19 EME31221.1 - 0.0005 19.5 0.0 0.0015 17.9 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CRM1_C PF08767.6 EME31222.1 - 5.9e-93 311.2 8.1 5.9e-93 311.2 5.6 2.8 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 EME31222.1 - 2.4e-34 118.3 1.5 2.4e-34 118.3 1.1 3.7 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EME31222.1 - 8.1e-16 57.7 0.5 4.3e-15 55.4 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EME31222.1 - 0.0094 15.9 0.3 65 4.0 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat Sugar_tr PF00083.19 EME31223.1 - 4.7e-75 252.8 18.8 5.1e-74 249.4 13.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31223.1 - 1.5e-22 79.7 31.8 2.9e-14 52.5 11.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME31225.1 - 1.9e-91 306.8 33.9 2.7e-91 306.4 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31225.1 - 1.4e-18 66.7 52.2 8.8e-16 57.5 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME31225.1 - 0.0007 18.0 12.3 0.0007 18.0 8.5 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EME31225.1 - 3.5 5.6 13.9 0.09 10.8 3.4 2.3 2 1 1 3 3 3 0 Transmembrane secretion effector WD40 PF00400.27 EME31227.1 - 5.4e-40 133.8 16.4 6e-11 41.7 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 EME31227.1 - 2.4e-06 27.2 0.4 7.8e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Apc4_WD40 PF12894.2 EME31227.1 - 0.043 13.3 1.0 0.38 10.2 0.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ARID PF01388.16 EME31228.1 - 8.4e-18 64.0 1.4 1.9e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 ARID/BRIGHT DNA binding domain PHD PF00628.24 EME31228.1 - 4.5e-06 26.2 16.8 1.6e-05 24.4 10.3 2.3 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.20 EME31229.1 - 5.5e-26 90.2 0.1 1.1e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain DUF1539 PF07560.6 EME31229.1 - 0.073 12.9 2.2 0.48 10.2 0.3 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1539) YojJ PF10372.4 EME31229.1 - 0.12 12.2 0.5 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF3538 PF12057.3 EME31229.1 - 0.16 11.6 1.7 0.88 9.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) MutL_C PF08676.6 EME31230.1 - 2.3e-09 36.9 0.2 6.8e-09 35.4 0.1 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain XPG_I_2 PF12813.2 EME31230.1 - 0.1 12.0 2.1 0.31 10.5 0.8 1.9 1 1 1 2 2 2 0 XPG domain containing adh_short PF00106.20 EME31231.1 - 4.4e-24 85.2 0.0 1.4e-23 83.6 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME31231.1 - 5.6e-09 36.1 0.0 2.7e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME31231.1 - 5.7e-09 35.8 0.0 8.7e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME31231.1 - 1.2e-07 31.3 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME31231.1 - 0.0088 16.0 0.1 0.023 14.7 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME31231.1 - 0.084 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_carr PF00153.22 EME31232.1 - 3.8e-52 173.9 0.8 1.9e-17 62.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 EME31233.1 - 1.1e-17 63.7 0.0 2.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.16 EME31234.1 - 1.1e-17 63.7 0.0 2.3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Menin PF05053.8 EME31235.1 - 0.06 11.5 3.8 0.073 11.2 2.6 1.0 1 0 0 1 1 1 0 Menin FGF-BP1 PF06473.7 EME31235.1 - 3.8 7.0 11.7 0.5 9.9 5.1 1.6 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) RibD_C PF01872.12 EME31236.1 - 1e-41 142.7 0.0 1.5e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.17 EME31236.1 - 6e-20 70.7 0.1 1.7e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME31236.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain GLE1 PF07817.8 EME31237.1 - 8.4e-54 182.1 0.9 8.4e-54 182.1 0.6 2.4 2 0 0 2 2 2 2 GLE1-like protein Adap_comp_sub PF00928.16 EME31238.1 - 9.8e-55 185.4 0.0 1.2e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME31238.1 - 2.9e-08 33.5 0.3 5.1e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BLYB PF05289.6 EME31238.1 - 0.13 12.0 0.4 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein XFP PF03894.10 EME31239.1 - 0.0052 16.3 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase AAA_17 PF13207.1 EME31240.1 - 6.4e-08 33.4 0.1 3.5e-07 31.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EME31240.1 - 7.4e-08 32.3 0.0 1.1e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME31240.1 - 3e-05 23.1 0.0 6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EME31240.1 - 0.00013 22.2 0.2 0.00043 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EME31240.1 - 0.0014 18.3 0.1 0.005 16.5 0.0 2.0 2 1 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EME31240.1 - 0.0035 17.4 0.2 0.026 14.6 0.0 2.5 3 0 0 3 3 2 1 RNA helicase Cytidylate_kin2 PF13189.1 EME31240.1 - 0.004 17.0 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.1 EME31240.1 - 0.0074 16.2 0.1 0.052 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EME31240.1 - 0.0076 15.9 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 EME31240.1 - 0.009 16.2 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME31240.1 - 0.0094 15.9 0.1 0.042 13.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain PRK PF00485.13 EME31240.1 - 0.0095 15.5 0.3 0.14 11.6 0.1 2.4 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EME31240.1 - 0.017 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.18 EME31240.1 - 0.036 13.4 0.7 0.068 12.5 0.3 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SKI PF01202.17 EME31240.1 - 0.039 13.8 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_22 PF13401.1 EME31240.1 - 0.047 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2087 PF09860.4 EME31240.1 - 0.098 12.4 0.4 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) UPF0079 PF02367.12 EME31240.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2493 PF10686.4 EME31240.1 - 0.12 11.9 0.0 0.63 9.6 0.0 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF2493) AAA_31 PF13614.1 EME31240.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME31240.1 - 0.13 11.3 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2392 PF10288.4 EME31241.1 - 6.9e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EME31241.1 - 0.00019 21.0 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Endonuclease_7 PF02945.10 EME31241.1 - 0.044 13.4 5.4 0.11 12.2 0.2 2.6 2 0 0 2 2 2 0 Recombination endonuclease VII 6PF2K PF01591.13 EME31241.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DZR PF12773.2 EME31241.1 - 6.8 6.6 10.5 9 6.2 1.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.1 EME31241.1 - 9.4 5.5 7.0 0.66 9.2 1.0 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger R3H-assoc PF13902.1 EME31243.1 - 2.8e-06 27.3 0.3 5.1e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H-assoc PF13902.1 EME31244.1 - 2.8e-06 27.3 0.3 5.1e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain Globin PF00042.17 EME31245.1 - 1.2e-15 57.7 0.0 3.7e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Globin Protoglobin PF11563.3 EME31245.1 - 0.065 12.8 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 Protoglobin MHCassoc_trimer PF08831.5 EME31245.1 - 0.17 11.7 0.9 0.55 10.1 0.0 2.1 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain PEMT PF04191.8 EME31246.1 - 1.2e-25 89.6 3.2 1.2e-25 89.6 2.2 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase CLP_protease PF00574.18 EME31247.1 - 2.9e-79 264.9 0.0 3.6e-79 264.6 0.0 1.1 1 0 0 1 1 1 1 Clp protease WD40 PF00400.27 EME31249.1 - 3.2e-19 68.0 42.8 7.9e-06 25.5 0.0 10.8 12 0 0 12 12 12 6 WD domain, G-beta repeat Lem_TRP PF08262.6 EME31249.1 - 0.11 12.3 0.2 0.34 10.7 0.1 1.9 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide HEAT_2 PF13646.1 EME31251.1 - 1.1e-36 124.9 0.8 5.6e-18 65.0 0.1 3.0 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EME31251.1 - 2.7e-20 70.7 0.1 0.00044 20.4 0.0 6.0 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.17 EME31251.1 - 7.2e-19 66.1 1.1 0.0045 16.9 0.0 6.7 5 1 0 6 6 6 6 HEAT repeat HEAT_EZ PF13513.1 EME31251.1 - 4.5e-16 58.8 0.3 0.068 13.6 0.0 5.5 5 1 1 6 6 6 6 HEAT-like repeat Arm PF00514.18 EME31251.1 - 3.1e-07 29.9 0.3 0.54 10.1 0.0 4.3 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 EME31251.1 - 0.00083 18.8 0.1 0.5 9.8 0.0 2.9 2 1 2 4 4 4 2 Domain of unknown function (DUF4042) Cnd1 PF12717.2 EME31251.1 - 0.0021 17.9 1.1 2.8 7.7 0.0 4.1 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EME31251.1 - 0.058 13.3 2.5 5 7.1 0.0 3.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion SUI1 PF01253.17 EME31252.1 - 8e-28 96.0 3.9 9.4e-28 95.8 2.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 ATPase-cat_bd PF12156.3 EME31252.1 - 0.31 11.5 2.2 0.41 11.2 1.5 1.5 1 1 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Ribosomal_L28e PF01778.12 EME31253.1 - 2.8e-31 108.3 0.2 2.8e-31 108.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EME31253.1 - 6.8e-17 61.4 16.2 2.1e-16 59.8 11.3 1.9 1 0 0 1 1 1 1 Mak16 protein C-terminal region UPF0066 PF01980.11 EME31253.1 - 0.037 13.9 0.6 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0066 Thioredoxin_5 PF13743.1 EME31253.1 - 0.12 11.8 3.6 0.27 10.7 0.1 2.5 1 1 1 2 2 2 0 Thioredoxin zf-RING_2 PF13639.1 EME31254.1 - 3.9e-05 23.4 20.7 3.9e-05 23.4 14.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME31254.1 - 0.0002 21.3 21.5 0.0002 21.3 14.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31254.1 - 0.00033 20.2 17.3 0.00033 20.2 12.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4455 PF14643.1 EME31254.1 - 0.0024 16.5 3.9 0.0038 15.9 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) MATH PF00917.21 EME31254.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 MATH domain Tektin PF03148.9 EME31254.1 - 0.028 12.9 9.0 0.033 12.7 0.4 2.1 1 1 1 2 2 2 0 Tektin family TMF_TATA_bd PF12325.3 EME31254.1 - 0.06 13.0 5.5 0.17 11.5 3.8 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mer2 PF09074.5 EME31254.1 - 0.061 13.2 3.7 0.12 12.2 2.6 1.4 1 0 0 1 1 1 0 Mer2 bZIP_1 PF00170.16 EME31254.1 - 0.43 10.5 8.5 3.2 7.7 0.2 3.2 2 1 1 3 3 3 0 bZIP transcription factor BLOC1_2 PF10046.4 EME31254.1 - 0.44 10.7 6.9 0.44 10.7 0.7 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.1 EME31254.1 - 6.4 6.4 8.3 2 8.1 3.6 1.7 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EME31254.1 - 7.6 6.2 10.5 4.4 7.0 4.6 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-B_box PF00643.19 EME31255.1 - 1.3e-05 24.9 6.2 1.3e-05 24.9 4.3 2.7 2 1 0 2 2 1 1 B-box zinc finger zf-RING_2 PF13639.1 EME31255.1 - 2.9e-05 23.8 20.7 2.9e-05 23.8 14.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME31255.1 - 0.00015 21.7 21.5 0.00015 21.7 14.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31255.1 - 0.00024 20.6 17.3 0.00024 20.6 12.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4455 PF14643.1 EME31255.1 - 0.0015 17.2 3.8 0.0024 16.5 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) Tektin PF03148.9 EME31255.1 - 0.015 13.8 9.0 0.025 13.1 0.7 2.1 1 1 1 2 2 2 0 Tektin family Mer2 PF09074.5 EME31255.1 - 0.03 14.2 3.3 0.062 13.2 2.3 1.5 1 0 0 1 1 1 0 Mer2 TMF_TATA_bd PF12325.3 EME31255.1 - 0.063 13.0 6.1 0.18 11.5 4.2 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IGR PF09597.5 EME31255.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 IGR protein motif BLOC1_2 PF10046.4 EME31255.1 - 0.22 11.6 7.0 0.29 11.2 0.6 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 EME31255.1 - 0.25 11.3 8.5 2.4 8.1 0.2 3.1 2 1 1 3 3 3 0 bZIP transcription factor UPF0449 PF15136.1 EME31255.1 - 1.1 9.5 4.3 2 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Nup54 PF13874.1 EME31255.1 - 3.2 7.4 8.0 1.1 8.8 3.4 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EME31255.1 - 6.4 6.5 10.8 3.5 7.3 4.8 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_23 PF13476.1 EME31256.1 - 8.3 6.6 7.5 9.4 6.5 5.2 1.1 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EME31257.1 - 3.2e-91 306.1 23.3 3.9e-91 305.8 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31257.1 - 1.6e-28 99.4 25.2 1.6e-28 99.4 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME31257.1 - 6.4e-05 21.3 5.4 6.4e-05 21.3 3.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NUDIX PF00293.23 EME31258.1 - 8.6e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain UPF0061 PF02696.9 EME31259.1 - 1.3e-108 363.3 0.2 1.8e-108 362.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF2334 PF10096.4 EME31259.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TPR_11 PF13414.1 EME31261.1 - 3.9e-18 64.8 0.2 7.4e-10 38.3 0.0 3.4 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EME31261.1 - 2.8e-09 36.1 0.1 0.0001 21.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME31261.1 - 7.2e-08 31.7 0.7 0.0043 16.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME31261.1 - 0.00015 22.3 0.1 0.06 14.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME31261.1 - 0.0017 17.9 0.0 3.9 7.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME31261.1 - 0.0059 16.5 0.2 0.88 9.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME31261.1 - 0.013 15.6 0.0 0.27 11.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME31261.1 - 0.032 14.8 0.6 7.2 7.5 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME31261.1 - 0.12 12.2 0.4 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3835 PF12927.2 EME31261.1 - 0.4 11.6 5.8 1.9 9.4 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3835) TPX2 PF06886.6 EME31261.1 - 8.5 6.5 11.3 1.7 8.7 3.2 2.7 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) zf-TRAF PF02176.13 EME31262.1 - 1.5e-08 34.8 8.0 0.0012 19.1 3.0 2.8 1 1 1 2 2 2 2 TRAF-type zinc finger bZIP_2 PF07716.10 EME31262.1 - 0.0099 15.6 15.1 0.021 14.6 10.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME31262.1 - 0.096 12.9 14.4 0.2 11.9 10.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EME31262.1 - 0.12 12.3 18.4 0.12 12.3 11.7 1.9 1 1 0 1 1 1 0 bZIP transcription factor Sina PF03145.11 EME31262.1 - 0.4 10.2 6.1 1.8 8.1 2.6 2.2 1 1 1 2 2 2 0 Seven in absentia protein family ABC_tran PF00005.22 EME31263.1 - 1.2e-46 158.3 0.0 2.1e-22 79.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EME31263.1 - 5.4e-21 74.2 11.0 3.5e-20 71.6 4.5 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 EME31263.1 - 3.8e-19 69.7 4.4 8.1e-05 22.7 0.4 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EME31263.1 - 5.1e-12 45.5 0.3 0.021 14.0 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EME31263.1 - 1.4e-10 42.0 0.2 9.1e-05 23.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EME31263.1 - 1.7e-07 30.6 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EME31263.1 - 1.8e-06 27.2 0.4 0.81 8.6 0.0 4.1 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EME31263.1 - 2.6e-06 27.6 0.5 0.076 13.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EME31263.1 - 3.3e-06 26.3 0.0 0.096 11.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME31263.1 - 6.6e-06 26.5 13.2 0.0022 18.3 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EME31263.1 - 7.6e-06 25.5 0.1 0.14 11.5 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain Miro PF08477.8 EME31263.1 - 1.4e-05 25.5 0.0 0.15 12.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 EME31263.1 - 1.6e-05 24.7 0.6 0.064 12.9 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 EME31263.1 - 2.1e-05 24.4 0.0 0.024 14.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EME31263.1 - 2.9e-05 24.3 1.4 0.22 11.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EME31263.1 - 3.7e-05 23.7 0.0 0.094 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EME31263.1 - 4.3e-05 23.4 0.0 0.15 11.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EME31263.1 - 9e-05 22.1 0.1 0.58 9.7 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.1 EME31263.1 - 0.00016 21.3 0.1 0.98 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EME31263.1 - 0.00021 21.4 0.0 0.55 10.4 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME31263.1 - 0.00025 20.7 0.0 0.65 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EME31263.1 - 0.00034 20.0 0.0 0.34 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EME31263.1 - 0.00045 20.0 0.0 0.049 13.5 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EME31263.1 - 0.00087 19.1 0.5 1.7 8.4 0.0 2.9 2 1 0 2 2 2 2 Dynamin family AAA_33 PF13671.1 EME31263.1 - 0.0011 18.8 0.1 1.1 9.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME31263.1 - 0.0012 19.0 0.3 1.5 8.9 0.0 3.5 3 1 1 4 4 4 1 RNA helicase DUF87 PF01935.12 EME31263.1 - 0.0016 18.3 0.0 0.63 9.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 NB-ARC PF00931.17 EME31263.1 - 0.0018 17.1 0.1 0.086 11.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 EME31263.1 - 0.0047 16.5 0.0 0.85 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME31263.1 - 0.006 16.5 0.7 1.1 9.2 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain NTPase_1 PF03266.10 EME31263.1 - 0.0087 15.7 0.0 2.3 7.9 0.0 2.8 2 0 0 2 2 2 1 NTPase cobW PF02492.14 EME31263.1 - 0.018 14.5 0.0 4.2 6.7 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EME31263.1 - 0.024 14.0 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 EME31263.1 - 0.036 13.5 0.0 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EME31263.1 - 0.041 13.3 0.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EME31263.1 - 0.049 13.1 0.6 6.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EME31263.1 - 0.065 12.9 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EME31263.1 - 0.11 12.1 0.2 14 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EME31263.1 - 0.57 9.5 2.9 4.7 6.6 0.0 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain bZIP_1 PF00170.16 EME31264.1 - 0.0025 17.7 2.1 0.0053 16.6 1.1 1.8 1 1 1 2 2 2 1 bZIP transcription factor DUF972 PF06156.8 EME31264.1 - 0.0028 17.9 2.4 0.0066 16.7 1.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) GAS PF13851.1 EME31264.1 - 0.021 14.0 1.9 0.033 13.3 1.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.13 EME31264.1 - 0.051 13.5 0.4 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EME31264.1 - 0.058 13.6 3.7 0.12 12.6 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3166 PF11365.3 EME31264.1 - 0.076 13.4 3.0 0.39 11.1 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) CCDC155 PF14662.1 EME31264.1 - 0.08 12.5 4.7 0.13 11.8 3.3 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 EME31264.1 - 0.094 12.2 0.6 0.19 11.2 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Rubis-subs-bind PF09273.6 EME31265.1 - 4.1e-14 52.6 0.2 7.1e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding RRM_1 PF00076.17 EME31266.1 - 3.1e-26 90.7 0.9 6.1e-13 48.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31266.1 - 1.1e-23 82.9 0.2 7.4e-11 41.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31266.1 - 8.1e-17 60.8 0.3 6.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EME31266.1 - 1.5e-05 24.8 0.0 0.094 12.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding domain TC1 PF15063.1 EME31266.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Thyroid cancer protein 1 tRNA_U5-meth_tr PF05958.6 EME31268.1 - 6.1e-09 35.0 0.0 2.3e-07 29.8 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.11 EME31268.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EME31268.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.9 EME31268.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Abhydrolase_5 PF12695.2 EME31271.1 - 4.6e-25 88.0 0.1 8.6e-25 87.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME31271.1 - 1.9e-21 77.0 2.9 2e-21 76.9 1.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME31271.1 - 2e-07 30.4 0.0 0.016 14.4 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EME31271.1 - 1.1e-06 28.4 0.0 0.0023 17.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.3 EME31271.1 - 0.0011 18.0 0.1 1.3 7.9 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Hydrolase_4 PF12146.3 EME31271.1 - 0.0025 17.6 0.2 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EME31271.1 - 0.0062 16.0 0.1 0.55 9.6 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase LIP PF03583.9 EME31271.1 - 0.02 14.0 0.3 0.26 10.4 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DUF829 PF05705.9 EME31271.1 - 0.026 14.2 0.0 0.074 12.7 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) DLH PF01738.13 EME31271.1 - 0.03 13.6 0.1 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 EME31271.1 - 0.062 12.9 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EME31271.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Pyr_redox_2 PF07992.9 EME31272.1 - 3.1e-46 157.8 8.2 7.7e-29 101.0 2.0 3.5 2 1 2 4 4 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME31272.1 - 9.3e-37 125.4 0.1 1.8e-36 124.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EME31272.1 - 1.5e-25 89.4 2.7 1e-19 70.7 0.1 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME31272.1 - 4.9e-13 48.9 0.3 2.8e-10 39.8 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EME31272.1 - 6.1e-12 45.1 0.7 5.1e-10 38.7 0.6 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME31272.1 - 7.6e-12 45.7 0.1 1.3e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME31272.1 - 2.5e-09 36.1 12.0 0.00044 18.8 3.6 4.1 2 2 1 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EME31272.1 - 4.9e-09 36.0 2.3 7.6e-06 25.8 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME31272.1 - 2.3e-08 33.3 8.8 0.0028 16.6 0.3 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME31272.1 - 1e-07 31.1 0.3 0.008 15.1 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EME31272.1 - 2.4e-07 29.9 8.7 7.7e-06 24.9 2.3 3.8 3 2 1 4 4 4 1 FAD binding domain Thi4 PF01946.12 EME31272.1 - 4.4e-05 22.6 1.3 0.0001 21.5 0.3 2.2 1 1 1 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EME31272.1 - 0.00023 20.7 0.2 0.085 12.4 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EME31272.1 - 0.00068 18.6 0.2 0.066 12.1 0.0 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME31272.1 - 0.00071 18.7 8.0 0.046 12.7 0.7 3.6 3 1 1 4 4 4 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EME31272.1 - 0.0029 17.0 3.0 0.029 13.7 0.1 2.8 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EME31272.1 - 0.0074 15.9 1.2 0.76 9.4 0.0 2.6 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EME31272.1 - 0.045 14.0 0.0 10 6.4 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 EME31272.1 - 0.12 12.6 1.0 9 6.6 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EME31272.1 - 1.1 8.1 3.5 8.4 5.3 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HEAT PF02985.17 EME31273.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat Arm PF00514.18 EME31274.1 - 2.3e-92 300.0 10.8 2.8e-13 49.1 0.0 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME31274.1 - 1.6e-27 95.6 0.0 2.8e-10 40.3 0.0 5.0 2 2 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EME31274.1 - 1e-23 83.1 5.7 9.7e-07 29.0 0.0 7.0 6 3 2 8 8 7 4 HEAT-like repeat HEAT PF02985.17 EME31274.1 - 1.6e-20 71.2 1.2 8.6e-06 25.4 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.15 EME31274.1 - 1.7e-18 66.5 7.4 3.2e-18 65.6 5.1 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EME31274.1 - 2.4e-07 30.1 0.1 0.082 12.0 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EME31274.1 - 3e-07 29.1 0.0 0.031 12.5 0.0 3.5 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EME31274.1 - 1.4e-06 28.2 0.0 0.056 13.3 0.0 4.3 3 1 0 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 EME31274.1 - 1.4e-06 28.0 1.7 2.3 8.2 0.0 5.4 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EME31274.1 - 0.0003 20.9 0.1 1.7 9.3 0.0 5.1 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EME31274.1 - 0.00054 18.3 0.2 0.013 13.7 0.1 2.3 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit SURF6 PF04935.7 EME31274.1 - 0.16 11.2 10.9 0.25 10.6 7.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF3689 PF12463.3 EME31275.1 - 5.5e-53 179.7 6.5 7e-43 146.5 3.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) Spore_III_AB PF09548.5 EME31276.1 - 0.0098 15.6 5.4 2.5 7.8 0.3 3.6 2 1 0 3 3 3 2 Stage III sporulation protein AB (spore_III_AB) GAF_3 PF13492.1 EME31276.1 - 0.038 14.0 0.2 0.3 11.1 0.0 2.4 2 0 0 2 2 2 0 GAF domain DUF507 PF04368.8 EME31276.1 - 2.3 7.7 15.5 0.19 11.3 1.7 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF507) CBFD_NFYB_HMF PF00808.18 EME31277.1 - 3.4e-13 49.4 0.3 1.1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME31277.1 - 0.00013 22.0 0.6 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ALS_ss_C PF10369.4 EME31277.1 - 0.085 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Small subunit of acetolactate synthase SOBP PF15279.1 EME31277.1 - 1.2 9.4 8.2 1.6 9.0 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein BORG_CEP PF14957.1 EME31277.1 - 3.7 8.4 7.0 3.1 8.7 3.9 1.7 1 1 0 1 1 1 0 Cdc42 effector Peptidase_M24 PF00557.19 EME31278.1 - 5.3e-51 173.1 0.1 6.5e-51 172.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 EME31278.1 - 0.16 12.3 0.0 4.2 7.8 0.0 2.2 2 0 0 2 2 2 0 ATP cone domain SpoU_methylase PF00588.14 EME31279.1 - 2.7e-31 108.3 0.0 3.5e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SAE2 PF08573.5 EME31280.1 - 8.4e-06 26.3 8.7 8.4e-06 26.3 6.0 4.3 3 2 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus PolyA_pol PF01743.15 EME31281.1 - 1.8e-25 89.6 0.1 3e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EME31281.1 - 6.3e-05 22.4 0.0 0.00021 20.8 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Mt_ATP-synt_D PF05873.7 EME31282.1 - 1.1e-05 25.1 4.0 1.9e-05 24.3 2.7 1.4 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) UvrD-helicase PF00580.16 EME31282.1 - 0.062 12.5 0.9 0.089 12.0 0.7 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain OmpH PF03938.9 EME31282.1 - 0.079 12.8 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1104 PF06518.6 EME31282.1 - 0.18 11.9 4.9 0.21 11.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) ING PF12998.2 EME31282.1 - 3.4 8.0 9.5 0.8 10.0 3.9 2.0 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M1 PF01433.15 EME31283.1 - 9.3e-60 202.7 0.0 1.3e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EME31283.1 - 3.8e-26 91.3 0.2 1.1e-25 89.8 0.1 1.8 1 1 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EME31283.1 - 5.7e-13 49.0 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Chloroa_b-bind PF00504.16 EME31284.1 - 1.8e-41 141.9 0.0 2.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.16 EME31285.1 - 1.3e-40 139.2 0.0 1.6e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein HSP20 PF00011.16 EME31286.1 - 2.2e-18 66.0 2.3 8.7e-17 60.8 1.6 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 EME31286.1 - 0.0014 18.3 0.7 0.0023 17.6 0.5 1.4 1 0 0 1 1 1 1 GvpH CBF PF03914.12 EME31287.1 - 0.1 12.0 2.5 0.15 11.5 0.1 2.5 3 0 0 3 3 3 0 CBF/Mak21 family C1_4 PF07975.7 EME31288.1 - 0.14 12.2 2.3 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Auto_anti-p27 PF06677.7 EME31288.1 - 4.5 7.1 7.3 6.9 6.5 0.0 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) WD40 PF00400.27 EME31290.1 - 2.7e-34 115.7 12.2 3.4e-06 26.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat TAP_C PF03943.8 EME31291.1 - 0.00062 19.1 1.4 0.0014 17.9 0.2 2.2 2 0 0 2 2 2 1 TAP C-terminal domain zf-4CXXC_R1 PF10497.4 EME31291.1 - 0.35 11.0 10.8 1.1 9.3 7.5 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 WD40 PF00400.27 EME31292.1 - 6e-15 54.4 9.7 4e-07 29.6 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 EME31292.1 - 4e-09 36.1 12.4 4e-09 36.1 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME31292.1 - 0.014 15.4 10.0 0.048 13.7 7.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME31292.1 - 0.018 14.6 9.0 0.041 13.5 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME31292.1 - 0.04 13.7 3.2 0.11 12.3 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EME31292.1 - 0.14 12.1 13.7 0.46 10.5 9.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31292.1 - 0.18 11.5 10.4 0.46 10.2 7.2 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EME31292.1 - 0.59 9.8 12.9 1.5 8.5 8.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Microtub_assoc PF07989.6 EME31293.1 - 7.9e-07 28.8 0.9 7.9e-07 28.8 0.6 5.3 5 2 1 6 6 6 1 Microtubule associated Retrotrans_gag PF03732.12 EME31293.1 - 0.37 10.9 9.3 7.4 6.7 1.6 3.7 3 1 0 3 3 3 0 Retrotransposon gag protein FAD_binding_3 PF01494.14 EME31294.1 - 3.1e-16 59.4 0.0 6.4e-15 55.0 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EME31294.1 - 0.0003 19.7 0.0 0.024 13.4 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.9 EME31294.1 - 0.0022 16.6 0.0 0.064 11.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EME31294.1 - 0.003 17.5 0.1 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME31294.1 - 0.051 12.4 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ELO PF01151.13 EME31295.1 - 2.6e-60 203.8 17.1 2.9e-60 203.6 11.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pam17 PF08566.5 EME31295.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF4389 PF14333.1 EME31295.1 - 0.81 9.4 8.6 2.4 7.9 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Mpv17_PMP22 PF04117.7 EME31298.1 - 3e-24 84.4 1.0 4e-24 84.0 0.3 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 EME31299.1 - 3e-24 84.4 1.0 4e-24 84.0 0.3 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family DEAD PF00270.24 EME31300.1 - 1.9e-33 115.3 0.0 6.1e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31300.1 - 1.1e-16 60.4 0.0 2.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME31300.1 - 5.7e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME31300.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.1 EME31300.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NST1 PF13945.1 EME31300.1 - 0.14 12.2 0.6 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DEAD PF00270.24 EME31301.1 - 1.9e-33 115.3 0.0 6.1e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31301.1 - 1.1e-16 60.4 0.0 2.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME31301.1 - 5.7e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME31301.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.1 EME31301.1 - 0.071 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NST1 PF13945.1 EME31301.1 - 0.14 12.2 0.6 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Ssl1 PF04056.9 EME31302.1 - 3.2e-63 212.8 0.0 4.1e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EME31302.1 - 3.1e-10 40.4 0.0 4.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EME31302.1 - 0.0068 16.1 0.0 0.045 13.4 0.0 2.0 1 1 1 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 EME31303.1 - 5e-63 212.1 0.0 6.5e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EME31303.1 - 2e-12 46.9 11.8 2e-12 46.9 8.1 3.5 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 EME31303.1 - 4.6e-10 39.8 0.0 6.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain PhnA_Zn_Ribbon PF08274.7 EME31303.1 - 8.5 6.2 15.5 0.47 10.2 0.7 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Abhydrolase_6 PF12697.2 EME31304.1 - 2.1e-31 109.5 0.0 2.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME31304.1 - 3.6e-19 69.2 0.0 3.8e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME31304.1 - 1.2e-14 54.3 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME31304.1 - 3.6e-06 26.7 0.1 6.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EME31304.1 - 0.00047 19.6 0.0 0.00091 18.7 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EME31304.1 - 0.002 18.4 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EME31304.1 - 0.0063 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydro_lipase PF04083.11 EME31304.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Chlorophyllase PF07224.6 EME31304.1 - 0.041 12.6 0.0 0.24 10.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Chlorophyllase2 PF12740.2 EME31304.1 - 0.045 12.6 0.1 0.28 10.0 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EME31304.1 - 0.046 13.1 0.2 2.1 7.7 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Tim17 PF02466.14 EME31306.1 - 2.2e-11 43.9 0.4 4.7e-11 42.8 0.3 1.5 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ER_lumen_recept PF00810.13 EME31307.1 - 1.5e-54 184.4 6.4 2.5e-54 183.7 4.4 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF368 PF04018.8 EME31307.1 - 0.02 14.0 1.0 0.024 13.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) PQ-loop PF04193.9 EME31307.1 - 1 8.9 8.3 1.2 8.7 0.3 3.9 3 1 1 4 4 4 0 PQ loop repeat HORMA PF02301.13 EME31308.1 - 1.7e-42 145.2 3.2 1.9e-42 145.0 2.2 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EME31308.1 - 0.0015 17.9 0.9 0.0021 17.5 0.2 1.5 2 0 0 2 2 2 1 Autophagy-related protein 13 Propeptide_C25 PF08126.6 EME31308.1 - 0.018 14.0 0.3 0.027 13.4 0.2 1.3 1 0 0 1 1 1 0 Propeptide_C25 HORMA PF02301.13 EME31309.1 - 5.1e-42 143.7 3.0 5.8e-42 143.5 2.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EME31309.1 - 0.011 15.2 0.9 0.014 14.7 0.2 1.5 2 0 0 2 2 2 0 Autophagy-related protein 13 HAUS4 PF14735.1 EME31310.1 - 8.7e-06 25.2 9.1 1.4e-05 24.5 6.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 DUF4472 PF14739.1 EME31310.1 - 0.033 14.6 5.3 0.092 13.2 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) COMP PF11598.3 EME31310.1 - 0.042 13.9 0.1 0.17 11.9 0.1 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Glyco_trans_1_2 PF13524.1 EME31310.1 - 0.12 12.6 0.4 0.47 10.7 0.3 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF563 PF04577.9 EME31311.1 - 5e-20 72.2 0.0 1.1e-19 71.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) zf-CCCH PF00642.19 EME31313.1 - 2.6e-12 46.0 44.5 0.0004 19.9 1.9 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME31313.1 - 1.8e-05 24.5 34.6 0.068 13.1 0.0 6.2 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type AAA_30 PF13604.1 EME31314.1 - 4.6e-34 117.7 0.0 8.7e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EME31314.1 - 1e-23 83.4 0.1 2e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EME31314.1 - 4.1e-16 58.4 2.0 7.1e-16 57.7 0.6 2.0 2 0 0 2 2 2 1 Part of AAA domain HHH_4 PF14490.1 EME31314.1 - 8.5e-16 57.5 0.0 7.2e-15 54.5 0.0 2.6 1 1 0 2 2 2 1 Helix-hairpin-helix containing domain Viral_helicase1 PF01443.13 EME31314.1 - 2.2e-07 30.6 5.8 8.4e-05 22.1 0.1 3.3 3 1 0 3 3 2 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.1 EME31314.1 - 3.4e-07 30.3 0.0 1.9e-05 24.7 0.0 3.0 3 0 0 3 3 2 1 Helix-hairpin-helix domain AAA_11 PF13086.1 EME31314.1 - 6.5e-06 25.8 0.1 0.083 12.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EME31314.1 - 0.00011 22.3 0.0 0.00037 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EME31314.1 - 0.00022 20.8 0.7 0.00044 19.8 0.5 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EME31314.1 - 0.00024 20.1 0.1 0.0008 18.4 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase NACHT PF05729.7 EME31314.1 - 0.00035 20.2 0.4 0.0015 18.2 0.0 2.3 3 0 0 3 3 2 1 NACHT domain AAA_16 PF13191.1 EME31314.1 - 0.0017 18.3 0.0 0.0068 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EME31314.1 - 0.0018 17.9 0.1 0.0068 16.0 0.0 1.9 1 1 0 1 1 1 1 Helicase HHH_2 PF12826.2 EME31314.1 - 0.0019 18.0 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif UvrD-helicase PF00580.16 EME31314.1 - 0.002 17.4 0.6 0.016 14.5 0.1 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EME31314.1 - 0.0051 16.0 0.4 1.3 8.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 EME31314.1 - 0.008 15.1 0.0 0.019 13.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EME31314.1 - 0.015 16.0 0.1 0.086 13.6 0.1 2.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME31314.1 - 0.022 14.2 0.4 0.29 10.5 0.0 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein HHH_3 PF12836.2 EME31314.1 - 0.048 13.5 0.0 51 3.9 0.0 4.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif AAA PF00004.24 EME31314.1 - 0.049 13.8 0.2 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EME31314.1 - 0.055 12.5 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CARD PF00619.16 EME31314.1 - 0.057 13.2 0.1 0.19 11.5 0.1 1.9 2 0 0 2 2 1 0 Caspase recruitment domain AAA_18 PF13238.1 EME31314.1 - 0.067 13.5 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EME31314.1 - 0.074 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 EME31314.1 - 0.15 11.2 1.4 0.56 9.3 0.0 2.5 3 0 0 3 3 2 0 Chromatin associated protein KTI12 PDT PF00800.13 EME31315.1 - 9.4e-63 211.0 0.0 1.2e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EME31315.1 - 0.039 13.4 0.0 0.096 12.1 0.0 1.7 1 0 0 1 1 1 0 ACT domain zf-DHHC PF01529.15 EME31316.1 - 5.4e-38 130.0 16.0 5.4e-38 130.0 11.1 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase CitMHS PF03600.11 EME31316.1 - 0.028 13.0 5.0 0.046 12.3 0.1 2.1 2 0 0 2 2 2 0 Citrate transporter UL97 PF06734.7 EME31316.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 UL97 HemY_N PF07219.8 EME31316.1 - 0.048 13.2 0.1 0.048 13.2 0.1 2.3 2 1 0 2 2 2 0 HemY protein N-terminus O-antigen_lig PF13425.1 EME31316.1 - 0.12 12.3 11.9 0.074 13.0 2.6 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein UPF0542 PF15086.1 EME31316.1 - 0.23 11.1 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Spt4 PF06093.8 EME31316.1 - 9.8 6.1 9.0 6.9 6.6 4.7 1.8 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger KRTAP PF11759.3 EME31317.1 - 0.011 15.9 7.8 0.012 15.8 5.4 1.2 1 0 0 1 1 1 0 Keratin-associated matrix Galactosyl_T PF01762.16 EME31318.1 - 3.5e-34 118.1 0.1 2.2e-33 115.4 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Paramyxo_ncap PF00973.14 EME31318.1 - 0.17 10.5 0.1 0.22 10.1 0.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mob1_phocein PF03637.12 EME31319.1 - 2e-35 122.0 1.7 2.4e-35 121.7 1.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family UQ_con PF00179.21 EME31320.1 - 9.5e-25 86.6 0.0 1.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME31320.1 - 0.014 15.2 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 RWD domain Pkinase PF00069.20 EME31321.1 - 3.7e-58 196.7 0.0 1.2e-57 194.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31321.1 - 1.1e-25 90.1 0.0 1.3e-23 83.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31321.1 - 2.9e-06 27.1 0.0 0.0026 17.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME31321.1 - 2.9e-05 23.1 0.3 0.00021 20.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EME31321.1 - 0.016 14.3 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.14 EME31323.1 - 3e-58 195.8 0.0 5.8e-58 194.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME31323.1 - 5.9e-36 122.8 0.0 9.6e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME31323.1 - 6.4e-06 26.0 0.0 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EME31323.1 - 0.00016 21.0 0.0 0.00091 18.6 0.0 2.3 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EME31323.1 - 0.00017 21.0 0.1 0.00084 18.7 0.0 2.1 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EME31323.1 - 0.00042 20.6 0.1 0.0038 17.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EME31323.1 - 0.01 15.6 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EME31323.1 - 0.045 13.7 0.1 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain IF-2B PF01008.12 EME31324.1 - 9.9e-66 221.5 0.0 1.3e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TauE PF01925.14 EME31325.1 - 1.7e-34 119.3 36.5 3e-34 118.5 25.3 1.4 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE SRF-TF PF00319.13 EME31325.1 - 0.016 14.3 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Actin PF00022.14 EME31326.1 - 4.6e-151 502.7 0.0 5.2e-151 502.5 0.0 1.0 1 0 0 1 1 1 1 Actin SMC_N PF02463.14 EME31327.1 - 4.2e-62 209.2 45.2 1.5e-61 207.4 31.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME31327.1 - 1.5e-26 92.6 0.1 3.8e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME31327.1 - 2.2e-13 50.8 19.9 1.8e-08 34.6 0.3 4.1 2 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EME31327.1 - 7.6e-07 28.5 0.0 1.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.6 EME31327.1 - 0.00068 18.3 22.0 0.00068 18.3 15.2 7.3 3 2 3 7 7 7 4 Spc7 kinetochore protein Nup54 PF13874.1 EME31327.1 - 0.00069 19.2 8.2 0.00069 19.2 5.7 7.5 5 2 3 8 8 7 2 Nucleoporin complex subunit 54 ERM PF00769.14 EME31327.1 - 0.0012 18.4 17.7 0.0012 18.4 12.3 6.3 4 1 1 5 5 2 1 Ezrin/radixin/moesin family AAA_16 PF13191.1 EME31327.1 - 0.052 13.5 0.0 0.052 13.5 0.0 3.2 3 2 0 3 3 3 0 AAA ATPase domain PMEI PF04043.10 EME31327.1 - 0.2 11.5 3.0 0.46 10.3 0.3 2.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Barstar PF01337.13 EME31327.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.9 4 0 0 4 4 4 0 Barstar (barnase inhibitor) AAA_13 PF13166.1 EME31327.1 - 2.8 6.2 114.1 0.32 9.3 7.1 5.5 3 2 2 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 EME31327.1 - 9.2 5.3 34.5 0.014 14.6 3.0 5.4 3 2 1 6 6 6 0 Reovirus sigma C capsid protein GST_N_3 PF13417.1 EME31329.1 - 7e-28 96.6 0.0 9.3e-13 48.2 0.0 2.5 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME31329.1 - 1.6e-17 63.2 0.0 6.4e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EME31329.1 - 3e-07 30.3 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Prok-RING_4 PF14447.1 EME31329.1 - 0.084 12.4 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 BRO1 PF03097.13 EME31332.1 - 1.1e-29 103.4 0.2 1.4e-29 102.9 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain AIG2_2 PF13772.1 EME31333.1 - 8.2e-07 29.0 0.1 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EME31333.1 - 0.064 13.7 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family zf-C2H2_4 PF13894.1 EME31333.1 - 3.6 8.1 6.2 3.9 8.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HSF_DNA-bind PF00447.12 EME31334.1 - 5.2e-31 106.9 0.0 1.1e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE PF05739.14 EME31335.1 - 7.5e-18 63.9 2.2 7.5e-18 63.9 1.5 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EME31335.1 - 1.1e-06 28.6 7.2 1.4e-06 28.4 0.3 2.5 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EME31335.1 - 9.7e-05 22.0 3.6 0.00072 19.1 0.8 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 EME31335.1 - 0.38 10.9 5.2 0.98 9.5 0.7 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SNARE PF05739.14 EME31336.1 - 9.6e-18 63.6 2.2 9.6e-18 63.6 1.5 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EME31336.1 - 1.8e-06 28.0 7.4 1.9e-06 27.9 0.3 2.6 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EME31336.1 - 6.2e-05 22.6 2.5 0.00055 19.5 0.4 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 EME31336.1 - 0.63 10.2 5.2 1.3 9.2 0.7 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spore_III_AB PF09548.5 EME31338.1 - 0.12 12.0 8.0 0.25 11.0 0.4 3.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Spore_III_AB PF09548.5 EME31339.1 - 0.046 13.4 5.7 0.2 11.3 0.2 3.6 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Methyltransf_28 PF02636.12 EME31340.1 - 1.1e-65 221.6 0.0 1.4e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase BCDHK_Adom3 PF10436.4 EME31341.1 - 4.8e-52 175.7 0.0 6.7e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EME31341.1 - 1e-17 63.8 0.0 2.6e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME31341.1 - 0.0021 17.6 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_2 PF00890.19 EME31342.1 - 6.3e-123 410.6 3.8 8.6e-123 410.2 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EME31342.1 - 3.2e-44 149.8 0.1 5.1e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EME31342.1 - 3.8e-05 23.6 0.0 0.039 13.8 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31342.1 - 0.00026 20.1 0.5 0.5 9.4 0.1 2.7 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EME31342.1 - 0.0012 17.8 0.8 0.87 8.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME31342.1 - 0.05 12.6 0.6 0.084 11.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EME31342.1 - 0.39 9.5 2.2 5.4 5.7 2.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME31343.1 - 1.2e-123 413.0 3.5 1.7e-123 412.5 2.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EME31343.1 - 3.4e-44 149.7 0.1 5.5e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EME31343.1 - 3e-05 24.0 0.0 0.028 14.2 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31343.1 - 6.2e-05 22.1 0.6 0.11 11.6 0.1 2.7 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EME31343.1 - 0.00042 19.3 0.7 0.29 9.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME31343.1 - 0.029 13.4 0.5 0.045 12.8 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EME31343.1 - 0.27 10.0 2.0 3.2 6.5 2.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MMR_HSR1 PF01926.18 EME31344.1 - 6.9e-21 74.3 0.0 1.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME31344.1 - 1.5e-07 30.8 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EME31344.1 - 1.7e-06 27.5 0.0 0.0002 20.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EME31344.1 - 0.00011 22.1 0.3 0.5 10.1 0.2 2.3 1 1 0 2 2 2 2 Dynamin family Miro PF08477.8 EME31344.1 - 0.00032 21.1 0.0 0.00059 20.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EME31344.1 - 0.00037 19.6 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EME31344.1 - 0.00046 19.4 0.0 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 EME31344.1 - 0.012 14.6 0.2 0.17 10.8 0.1 2.6 1 1 0 1 1 1 0 Septin ABC_tran PF00005.22 EME31344.1 - 0.031 14.5 0.3 0.18 12.0 0.2 2.0 1 1 0 1 1 1 0 ABC transporter Ras PF00071.17 EME31344.1 - 0.033 13.5 0.2 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.1 EME31344.1 - 0.11 12.6 0.1 0.36 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain Y_Y_Y PF07495.8 EME31345.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Y_Y_Y domain Reo_sigmaC PF04582.7 EME31345.1 - 0.55 9.3 17.8 0.66 9.1 0.8 3.6 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EME31345.1 - 8 6.2 51.2 0.03 14.1 2.0 5.7 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) Keratin_B2 PF01500.12 EME31346.1 - 0.34 10.6 5.1 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein XhlA PF10779.4 EME31346.1 - 0.9 9.4 3.3 0.96 9.4 1.7 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Frigida PF07899.6 EME31346.1 - 1.6 7.3 6.6 2 7.0 4.6 1.1 1 0 0 1 1 1 0 Frigida-like protein Serglycin PF04360.7 EME31346.1 - 3.5 7.3 9.2 17 5.1 0.0 3.1 3 0 0 3 3 3 0 Serglycin DivIC PF04977.10 EME31347.1 - 0.022 14.2 1.9 1.8 8.1 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EME31347.1 - 0.46 10.3 3.3 0.18 11.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Mito_carr PF00153.22 EME31348.1 - 2.4e-56 187.4 0.7 1.9e-21 75.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein cNMP_binding PF00027.24 EME31348.1 - 5.3e-47 157.5 0.0 1.1e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF830 PF05708.7 EME31348.1 - 4.2e-13 49.5 0.0 4e-08 33.3 0.0 2.6 2 0 0 2 2 2 2 Orthopoxvirus protein of unknown function (DUF830) EF-hand_1 PF00036.27 EME31348.1 - 4e-07 28.8 0.1 0.00016 20.7 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EME31348.1 - 1.6e-05 24.9 3.0 0.0071 16.4 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EME31348.1 - 0.00013 21.5 0.1 0.0029 17.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EME31348.1 - 0.0045 16.5 0.1 0.028 14.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair CCDC-167 PF15188.1 EME31348.1 - 0.043 13.7 2.7 0.1 12.5 1.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 EF-hand_5 PF13202.1 EME31348.1 - 0.089 12.1 3.3 0.09 12.1 0.1 2.7 4 0 0 4 4 4 0 EF hand DUF565 PF04483.7 EME31350.1 - 3.8e-12 46.1 0.1 7.5e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF565) DUF1422 PF07226.6 EME31350.1 - 0.0084 15.8 0.6 0.068 12.9 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) zf-C3HC4_3 PF13920.1 EME31351.1 - 8.7e-12 44.5 8.7 1.8e-11 43.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME31351.1 - 0.00017 21.0 2.4 0.00017 21.0 1.6 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EME31351.1 - 0.00025 21.0 8.8 0.00025 21.0 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31351.1 - 0.00045 19.8 6.6 0.0011 18.6 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EME31351.1 - 0.0058 16.4 8.4 0.0058 16.4 5.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 EME31351.1 - 0.11 12.1 6.3 0.29 10.7 4.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GRAM PF02893.15 EME31352.1 - 5.3e-06 25.8 0.1 1.8e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 GRAM domain YjgP_YjgQ PF03739.9 EME31352.1 - 0.032 12.9 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3311 PF11755.3 EME31352.1 - 0.41 10.2 4.4 1 8.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Amidohydro_1 PF01979.15 EME31353.1 - 1.3e-08 34.9 0.1 3.8e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EME31353.1 - 1.2e-06 28.8 0.0 0.00036 20.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EME31353.1 - 0.0008 19.1 0.1 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME31353.1 - 0.0093 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EME31354.1 - 1.4e-08 34.8 0.1 4e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EME31354.1 - 1.3e-06 28.6 0.0 0.00037 20.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EME31354.1 - 0.00084 19.1 0.1 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME31354.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Peptidase_M76 PF09768.4 EME31355.1 - 4.8e-55 185.6 2.3 5.3e-55 185.5 1.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M76 PF09768.4 EME31356.1 - 2.2e-44 150.9 5.3 2.4e-44 150.8 3.7 1.0 1 0 0 1 1 1 1 Peptidase M76 family MRP-L51 PF10244.4 EME31356.1 - 0.068 13.2 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit ATG16 PF08614.6 EME31357.1 - 0.074 12.8 3.7 0.047 13.5 0.5 1.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) STAT_alpha PF01017.15 EME31357.1 - 0.075 12.7 3.9 0.11 12.2 0.1 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain BLOC1_2 PF10046.4 EME31357.1 - 0.099 12.7 0.6 0.099 12.7 0.4 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.8 EME31357.1 - 0.66 9.7 3.8 0.69 9.6 0.2 2.2 2 1 0 2 2 2 0 Sec20 Kinetocho_Slk19 PF12709.2 EME31357.1 - 1.7 8.7 7.0 0.78 9.8 1.6 2.3 2 1 0 2 2 2 0 Central kinetochore-associated ATG16 PF08614.6 EME31358.1 - 0.099 12.4 3.8 0.058 13.2 0.4 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) STAT_alpha PF01017.15 EME31358.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.1 1 1 1 2 2 2 0 STAT protein, all-alpha domain Apc9 PF12856.2 EME31358.1 - 0.15 12.1 3.7 0.49 10.5 2.4 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 9 BLOC1_2 PF10046.4 EME31358.1 - 1.1 9.4 9.4 0.13 12.4 0.4 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 EME31358.1 - 1.7 9.1 5.3 0.75 10.2 0.4 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Kinetocho_Slk19 PF12709.2 EME31358.1 - 3.3 7.8 7.4 1.1 9.3 1.9 2.3 2 0 0 2 2 2 0 Central kinetochore-associated DnaJ PF00226.26 EME31359.1 - 1.6e-24 85.4 1.5 3e-24 84.5 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME31359.1 - 2.3e-24 85.0 0.5 3e-21 75.0 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME31359.1 - 1.3e-15 57.2 18.7 2.2e-15 56.4 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EME31359.1 - 0.025 14.2 7.9 0.34 10.6 1.3 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Rep_fac-A_C PF08646.5 EME31359.1 - 0.16 11.6 2.1 3.2 7.4 0.2 2.4 1 1 1 2 2 2 0 Replication factor-A C terminal domain Zn_Tnp_IS1595 PF12760.2 EME31359.1 - 5.7 6.8 11.9 7.5 6.4 1.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EME31359.1 - 6.8 6.2 15.7 1.1 8.7 1.0 3.8 3 1 1 4 4 4 0 A2L zinc ribbon domain ATP-synt PF00231.14 EME31360.1 - 2.8e-80 269.7 4.0 3.4e-80 269.5 2.8 1.1 1 0 0 1 1 1 1 ATP synthase KfrA_N PF11740.3 EME31360.1 - 0.72 10.3 4.9 2.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term SUV3_C PF12513.3 EME31361.1 - 4e-16 58.1 0.3 1.4e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EME31361.1 - 2.8e-12 46.3 0.1 7.8e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME31361.1 - 0.0066 15.9 0.0 0.083 12.3 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase DED PF01335.16 EME31361.1 - 0.075 13.1 1.4 8.2 6.6 0.0 2.9 2 0 0 2 2 2 0 Death effector domain Pkinase PF00069.20 EME31362.1 - 5.6e-50 169.9 0.0 1.5e-49 168.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31362.1 - 9.5e-29 100.2 0.0 1.5e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31362.1 - 0.24 11.0 1.1 0.6 9.7 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family mRNA_triPase PF02940.10 EME31363.1 - 1.2e-10 41.4 0.8 1.2e-10 41.4 0.5 1.8 1 1 1 2 2 2 1 mRNA capping enzyme, beta chain Cyclin_N PF00134.18 EME31364.1 - 3.4e-22 78.3 3.6 5.5e-22 77.6 0.5 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME31364.1 - 0.00012 22.0 0.5 0.00012 22.0 0.4 2.8 2 1 2 4 4 4 2 Cyclin, C-terminal domain DUF2064 PF09837.4 EME31365.1 - 5e-28 97.1 0.0 9.2e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) dCMP_cyt_deam_1 PF00383.17 EME31365.1 - 6.5e-10 38.5 2.5 2e-09 37.0 1.7 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CofC PF01983.11 EME31365.1 - 0.0012 17.8 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Guanylyl transferase CofC like SPRY PF00622.23 EME31366.1 - 1.7e-14 53.9 0.2 1.5e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 SPRY domain SPRY PF00622.23 EME31367.1 - 1.4e-14 54.2 0.2 1.4e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 SPRY domain DUF3411 PF11891.3 EME31368.1 - 8.3e-47 159.2 0.0 1.2e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3411) Sugar_tr PF00083.19 EME31369.1 - 1.5e-31 109.4 23.1 1.4e-19 70.0 4.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME31369.1 - 8e-16 57.6 52.9 7.6e-13 47.8 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME31369.1 - 0.00033 19.2 7.5 0.00033 19.2 5.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Bromo_TP PF07524.8 EME31370.1 - 5.3e-05 22.8 0.1 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated NP1-WLL PF11733.3 EME31370.1 - 0.07 13.3 0.7 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Non-capsid protein NP1 SWIRM PF04433.12 EME31372.1 - 2.3e-32 110.9 0.0 7.3e-32 109.3 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EME31372.1 - 8.7e-10 38.5 0.0 5.9e-09 35.8 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EME31372.1 - 4.7e-09 35.6 5.6 7.9e-09 34.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EME31372.1 - 3.6e-06 26.9 0.1 2.1e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Chromo PF00385.19 EME31372.1 - 0.014 15.0 0.6 0.06 13.0 0.4 2.1 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain C1_2 PF03107.11 EME31372.1 - 0.29 11.2 10.2 0.52 10.4 7.1 1.4 1 0 0 1 1 1 0 C1 domain CPSase_L_D2 PF02786.12 EME31374.1 - 6.4e-108 358.8 0.2 8.5e-68 227.7 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME31374.1 - 4.5e-42 142.6 0.0 2.5e-20 72.6 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EME31374.1 - 8.4e-41 138.5 0.7 1.6e-40 137.6 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EME31374.1 - 1.6e-37 129.0 0.0 2e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ubiquitin PF00240.18 EME31374.1 - 3.6e-24 83.9 0.0 7.3e-24 82.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family ATPgrasp_Ter PF15632.1 EME31374.1 - 4.8e-22 78.1 0.0 6.3e-12 44.8 0.0 4.1 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME31374.1 - 7.2e-14 51.5 0.2 2.4e-10 40.0 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Rad60-SLD PF11976.3 EME31374.1 - 1.1e-13 50.6 0.0 2.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MGS PF02142.17 EME31374.1 - 2e-13 50.0 0.0 1.3e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EME31374.1 - 1.6e-10 40.6 0.1 2.7e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EME31374.1 - 5.9e-09 35.6 0.0 2.7e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EME31374.1 - 5.4e-07 29.3 0.4 0.0036 16.8 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EME31374.1 - 4.2e-06 26.7 1.0 0.0032 17.3 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.5 EME31374.1 - 2.1e-05 23.9 0.1 0.15 11.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EME31374.1 - 0.00065 18.9 0.0 0.055 12.6 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Ubiquitin_2 PF14560.1 EME31374.1 - 0.0075 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain GSH-S_ATP PF02955.11 EME31374.1 - 0.021 13.9 0.0 0.21 10.6 0.0 2.5 3 0 0 3 3 3 0 Prokaryotic glutathione synthetase, ATP-grasp domain HEM4 PF02602.10 EME31375.1 - 8.6e-21 74.2 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pantoate_transf PF02548.10 EME31376.1 - 4.2e-109 363.6 1.1 4.9e-109 363.4 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EME31376.1 - 1.4e-06 27.7 0.9 5.1e-06 25.8 0.6 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NanE PF04131.9 EME31376.1 - 0.059 12.3 0.1 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF544 PF04424.8 EME31377.1 - 6.1e-14 51.8 0.0 6.1e-14 51.8 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF544) CCDC50_N PF15295.1 EME31377.1 - 0.00039 20.3 3.4 0.00039 20.3 2.4 2.6 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 50 N-terminus Mito_carr PF00153.22 EME31378.1 - 5.4e-54 179.8 0.3 3.7e-19 68.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein HTH_21 PF13276.1 EME31378.1 - 0.096 12.7 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain Fcf1 PF04900.7 EME31379.1 - 1e-38 131.4 1.7 1e-38 131.4 1.2 1.8 2 0 0 2 2 2 1 Fcf1 WHIM1 PF15612.1 EME31379.1 - 0.018 14.9 0.1 0.079 12.9 0.0 2.1 1 1 1 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 RNA_pol PF00940.14 EME31380.1 - 7.6e-144 479.1 0.0 1.6e-143 478.0 0.0 1.6 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EME31380.1 - 4.5e-57 193.7 0.1 7.4e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA-synt_1c PF00749.16 EME31380.1 - 0.034 12.8 1.3 0.064 11.9 0.9 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain IL2 PF00715.12 EME31380.1 - 0.17 11.6 4.0 3.1 7.5 0.1 3.2 2 1 1 3 3 3 0 Interleukin 2 Tfb2 PF03849.9 EME31381.1 - 9.3e-83 277.8 8.9 1.3e-82 277.4 6.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Coatomer_E PF04733.9 EME31381.1 - 4.4e-57 193.4 1.9 6.3e-57 192.9 1.3 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EME31381.1 - 1.7e-14 53.9 11.9 3.9e-06 27.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME31381.1 - 2.2e-08 33.3 11.7 0.023 14.5 0.1 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME31381.1 - 2.4e-08 33.8 7.7 0.098 13.3 0.0 5.2 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME31381.1 - 9.7e-08 31.2 2.2 0.51 10.2 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EME31381.1 - 2.6e-07 30.6 3.0 0.042 13.9 0.1 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EME31381.1 - 6.5e-07 29.1 1.0 0.99 10.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME31381.1 - 1.3e-06 28.2 11.9 0.44 10.5 0.0 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EME31381.1 - 2.2e-06 28.1 10.5 0.24 12.1 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME31381.1 - 2.7e-06 27.4 3.1 0.21 12.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME31381.1 - 4.1e-06 26.3 6.9 0.023 14.3 0.4 4.2 3 1 1 4 4 4 2 TPR repeat Helicase_C_3 PF13625.1 EME31381.1 - 3.1e-05 23.7 0.0 9.3e-05 22.1 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HrpB1_HrpK PF09613.5 EME31381.1 - 6.1e-05 22.5 0.1 0.57 9.6 0.0 3.5 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_1 PF00515.23 EME31381.1 - 0.00016 21.1 7.4 2.2 8.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_45 PF14947.1 EME31381.1 - 0.00017 21.3 0.3 0.6 9.9 0.0 4.2 4 0 0 4 4 3 1 Winged helix-turn-helix TPR_21 PF09976.4 EME31381.1 - 0.00024 21.0 5.8 0.029 14.3 0.1 3.6 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME31381.1 - 0.00096 18.7 7.4 0.1 12.4 0.1 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 EME31381.1 - 0.0068 16.4 2.1 0.26 11.3 0.2 3.7 3 1 1 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.1 EME31381.1 - 0.011 15.8 2.8 11 6.1 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EME31381.1 - 0.012 15.4 0.3 24 5.1 0.0 4.3 5 0 0 5 5 4 0 PPR repeat HTH_27 PF13463.1 EME31381.1 - 0.048 13.9 0.0 8.4 6.8 0.0 3.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain DUF2007 PF09413.5 EME31381.1 - 0.058 13.2 1.0 0.2 11.4 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF2007) TPR_10 PF13374.1 EME31381.1 - 0.08 12.9 12.5 0.44 10.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.3 EME31381.1 - 0.23 11.0 2.6 18 4.9 0.0 3.0 3 1 0 3 3 2 0 YfdX protein TPR_17 PF13431.1 EME31381.1 - 2.8 8.3 8.9 95 3.5 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat AA_kinase PF00696.23 EME31382.1 - 9.9e-50 169.3 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EME31382.1 - 1.1e-08 34.4 0.3 9.8e-06 25.0 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EME31382.1 - 1.9e-08 33.6 0.5 0.005 16.2 0.1 2.5 2 0 0 2 2 2 2 ACT domain Archease PF01951.11 EME31382.1 - 0.0028 17.6 0.1 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) HTH_11 PF08279.7 EME31382.1 - 0.029 14.0 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 HTH domain DASH_Dad4 PF08650.5 EME31382.1 - 0.15 12.0 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad4 Ribosomal_S11 PF00411.14 EME31383.1 - 4.3e-42 142.7 0.6 5.5e-42 142.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Toprim_3 PF13362.1 EME31383.1 - 0.084 13.1 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Toprim domain DUF814 PF05670.8 EME31383.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) TPP1 PF10341.4 EME31384.1 - 0.0025 17.7 0.1 0.0061 16.5 0.1 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF383 PF04063.9 EME31384.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Ndc1_Nup PF09531.5 EME31385.1 - 1e-23 83.6 8.9 4.7e-14 51.7 2.5 2.3 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup DUF4006 PF13179.1 EME31385.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF4006) MCM PF00493.18 EME31386.1 - 1.3e-142 474.5 0.5 1.3e-142 474.5 0.4 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EME31386.1 - 1.7e-20 73.7 0.5 1.7e-20 73.7 0.3 2.8 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME31386.1 - 1.9e-07 30.4 0.0 1.6e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME31386.1 - 0.00013 21.7 0.0 0.00032 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME31386.1 - 0.00026 20.6 0.0 0.00068 19.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME31386.1 - 0.001 18.5 0.0 0.0034 16.8 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain HypA PF01155.14 EME31386.1 - 0.014 15.1 0.1 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EME31386.1 - 0.2 11.6 4.1 0.53 10.2 2.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EME31386.1 - 6.7 6.6 7.5 10 6.0 0.2 2.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RCC1 PF00415.13 EME31387.1 - 1.7e-46 156.2 17.9 1e-11 44.8 0.1 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME31387.1 - 1.3e-27 94.7 20.2 7.4e-08 31.8 0.1 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat ESSS PF10183.4 EME31388.1 - 0.43 11.0 0.1 0.43 11.0 0.1 2.8 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-grasp_2 PF08442.5 EME31389.1 - 1.3e-14 54.0 0.0 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EME31390.1 - 5.2e-21 74.7 0.0 2.8e-18 65.7 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EME31390.1 - 1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EME31390.1 - 5.9e-06 25.9 0.1 1.9e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.14 EME31390.1 - 6.4e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Alpha-amylase PF00128.19 EME31391.1 - 4.1e-26 92.1 0.0 1.2e-25 90.5 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Taxilin PF09728.4 EME31391.1 - 0.046 12.8 0.2 0.084 11.9 0.1 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1192 PF06698.6 EME31391.1 - 0.047 13.4 0.9 5.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Methyltransf_26 PF13659.1 EME31392.1 - 7.3e-08 32.4 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME31392.1 - 5.2e-07 30.2 0.0 6.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME31392.1 - 0.00028 20.4 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME31392.1 - 0.021 14.4 0.1 0.099 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EME31392.1 - 0.023 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EME31392.1 - 0.031 13.9 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EME31392.1 - 0.045 13.2 0.0 0.054 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EME31392.1 - 0.089 12.0 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.7 EME31392.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pkinase PF00069.20 EME31393.1 - 5.8e-76 255.0 0.0 7.7e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31393.1 - 1.4e-35 122.6 0.0 1.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31393.1 - 0.00025 20.1 0.0 0.019 13.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_C PF00433.19 EME31393.1 - 0.001 19.5 1.6 0.0022 18.4 1.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EME31393.1 - 0.01 14.9 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EME31393.1 - 0.025 13.1 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EME31393.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin PF00085.15 EME31394.1 - 9.5e-31 105.5 0.1 1e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME31394.1 - 1.4e-08 34.9 0.1 9.3e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME31394.1 - 4.2e-08 33.1 0.0 0.00016 21.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 EME31394.1 - 4.5e-06 26.2 0.0 2.2e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EME31394.1 - 1.9e-05 24.3 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 EME31394.1 - 9.2e-05 21.9 0.1 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 EME31394.1 - 0.00055 19.5 0.0 0.0006 19.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME31394.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EME31394.1 - 0.009 15.9 0.2 0.078 12.9 0.1 2.1 1 1 0 1 1 1 1 Glutaredoxin Lactamase_B_3 PF13483.1 EME31395.1 - 1.2e-24 86.8 0.0 1.6e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain THF_DHG_CYH_C PF02882.14 EME31396.1 - 9.8e-68 226.2 0.1 1.3e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EME31396.1 - 6.4e-45 151.9 0.1 1.1e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CitMHS PF03600.11 EME31397.1 - 1.3e-17 63.4 11.6 1.3e-17 63.4 8.1 1.9 1 1 1 2 2 2 2 Citrate transporter HSP20 PF00011.16 EME31398.1 - 3e-25 88.0 1.4 3.9e-25 87.6 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 EME31398.1 - 0.0041 16.8 0.2 0.071 12.8 0.1 2.2 2 0 0 2 2 2 1 BON domain Heme_oxygenase PF01126.15 EME31399.1 - 1.5e-42 145.4 0.1 1.7e-42 145.3 0.1 1.0 1 0 0 1 1 1 1 Heme oxygenase Borrelia_lipo_2 PF06238.6 EME31399.1 - 0.056 13.5 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein DUF3837 PF12939.2 EME31400.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) PHD PF00628.24 EME31402.1 - 1.7e-13 50.0 4.5 1.7e-13 50.0 3.1 3.0 2 1 1 3 3 3 1 PHD-finger zf-RING_2 PF13639.1 EME31402.1 - 8.4e-06 25.5 12.4 8.4e-06 25.5 8.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME31402.1 - 1e-05 25.0 9.5 1e-05 25.0 6.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31402.1 - 7.7e-05 22.6 13.8 7.7e-05 22.6 9.6 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME31402.1 - 0.00014 21.4 13.7 0.00014 21.4 9.5 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31402.1 - 0.0016 18.0 11.2 0.0016 18.0 7.8 3.6 3 1 1 4 4 4 1 zinc-RING finger domain PHD_2 PF13831.1 EME31402.1 - 0.014 14.7 0.7 0.014 14.7 0.5 3.6 3 1 1 4 4 4 0 PHD-finger zf-rbx1 PF12678.2 EME31402.1 - 0.27 11.3 14.1 0.036 14.1 4.3 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 EME31402.1 - 0.81 9.5 20.0 0.038 13.8 2.7 3.5 2 2 1 3 3 3 0 Double zinc ribbon zf-Apc11 PF12861.2 EME31402.1 - 1.1 9.1 13.6 0.88 9.4 3.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HEAT PF02985.17 EME31403.1 - 0.00084 19.2 0.5 4.1 7.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Chrome_Resist PF09828.4 EME31403.1 - 0.041 14.0 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Chromate resistance exported protein RPAP1_C PF08620.5 EME31404.1 - 0.00014 21.5 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal Voltage_CLC PF00654.15 EME31405.1 - 8.4e-90 301.3 24.2 8.4e-90 301.3 16.8 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EME31405.1 - 0.014 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 CBS domain ING PF12998.2 EME31406.1 - 1.4e-18 67.1 4.4 2e-18 66.6 3.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EME31406.1 - 1.8e-09 37.1 7.2 3.9e-09 36.0 5.0 1.6 1 0 0 1 1 1 1 PHD-finger DUF3584 PF12128.3 EME31406.1 - 3.5e-05 21.3 3.5 4.3e-05 21.0 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 EME31406.1 - 0.00032 18.5 8.6 0.00044 18.1 6.0 1.1 1 0 0 1 1 1 1 Myosin tail Laminin_II PF06009.7 EME31406.1 - 0.0021 17.8 3.6 0.024 14.3 1.8 2.1 1 1 1 2 2 2 1 Laminin Domain II DivIVA PF05103.8 EME31406.1 - 0.0042 17.1 4.5 0.0073 16.3 3.1 1.3 1 0 0 1 1 1 1 DivIVA protein DUF1192 PF06698.6 EME31406.1 - 0.005 16.6 0.6 0.012 15.3 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Cytochrom_C_2 PF01322.15 EME31406.1 - 0.006 17.1 0.5 0.0093 16.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome C' zf-HC5HC2H PF13771.1 EME31406.1 - 0.0075 16.3 0.2 0.0075 16.3 0.2 1.8 2 0 0 2 2 1 1 PHD-like zinc-binding domain NPV_P10 PF05531.7 EME31406.1 - 0.015 15.5 0.6 5.6 7.2 0.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-HC5HC2H_2 PF13832.1 EME31406.1 - 0.017 15.1 0.8 0.026 14.5 0.1 1.6 2 0 0 2 2 1 0 PHD-zinc-finger like domain AAA_13 PF13166.1 EME31406.1 - 0.022 13.2 1.6 0.026 12.9 1.1 1.1 1 0 0 1 1 1 0 AAA domain Cep57_CLD PF14073.1 EME31406.1 - 0.029 14.2 6.1 0.039 13.7 4.2 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 APG6 PF04111.7 EME31406.1 - 0.03 13.3 4.1 0.037 13.0 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3829 PF12889.2 EME31406.1 - 0.034 13.3 0.7 0.041 13.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4449 PF14613.1 EME31406.1 - 0.044 13.7 0.6 0.06 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF2408 PF10303.4 EME31406.1 - 0.045 13.8 1.6 0.088 12.9 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 EME31406.1 - 0.047 12.1 2.2 0.062 11.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IFT57 PF10498.4 EME31406.1 - 0.072 11.8 4.2 0.13 11.0 2.9 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 FadA PF09403.5 EME31406.1 - 0.15 12.0 5.3 0.24 11.4 3.7 1.2 1 0 0 1 1 1 0 Adhesion protein FadA AKNA PF12443.3 EME31406.1 - 0.16 11.9 2.6 0.85 9.6 0.5 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF972 PF06156.8 EME31406.1 - 0.19 12.0 5.6 2.1 8.7 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EME31406.1 - 0.19 11.2 12.1 0.23 11.0 7.8 1.5 1 1 1 2 2 2 0 IncA protein Spectrin PF00435.16 EME31406.1 - 0.25 11.6 6.3 3.8 7.8 1.7 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF1640 PF07798.6 EME31406.1 - 0.27 11.2 3.8 0.35 10.9 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4600 PF15372.1 EME31406.1 - 0.28 11.3 7.4 0.54 10.4 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) TMPIT PF07851.8 EME31406.1 - 0.33 9.9 2.3 0.45 9.5 1.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein RHH_1 PF01402.16 EME31406.1 - 0.52 10.2 2.8 0.33 10.9 0.2 2.0 2 0 0 2 2 1 0 Ribbon-helix-helix protein, copG family Prominin PF05478.6 EME31406.1 - 0.56 7.6 2.4 1.8 6.0 1.8 1.5 1 1 0 1 1 1 0 Prominin BLOC1_2 PF10046.4 EME31406.1 - 0.61 10.2 5.3 7.7 6.7 2.3 2.6 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 EME31406.1 - 0.63 10.8 4.1 7.6 7.3 2.6 2.3 1 1 1 2 2 2 0 Occludin homology domain TBPIP PF07106.8 EME31406.1 - 0.63 9.5 6.9 4.1 6.9 4.9 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lge1 PF11488.3 EME31406.1 - 0.71 10.1 8.6 5.7 7.2 0.1 2.7 2 1 1 3 3 2 0 Transcriptional regulatory protein LGE1 Prefoldin PF02996.12 EME31406.1 - 0.78 9.4 5.5 0.97 9.1 0.9 2.5 1 1 2 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 EME31406.1 - 1.1 7.0 3.6 1.2 6.8 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EME31406.1 - 1.8 8.6 7.8 13 5.8 5.4 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 EME31406.1 - 1.8 7.6 9.2 2.2 7.4 5.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 EME31406.1 - 2.1 8.1 8.1 4.1 7.2 1.5 2.6 1 1 0 2 2 2 0 Prefoldin subunit Mnd1 PF03962.10 EME31406.1 - 3.2 7.3 10.4 3.2 7.3 6.4 1.5 1 1 0 1 1 1 0 Mnd1 family Tropomyosin_1 PF12718.2 EME31406.1 - 3.5 7.4 13.5 2.7 7.8 7.6 2.0 2 1 0 2 2 1 0 Tropomyosin like Pescadillo_N PF06732.6 EME31407.1 - 9.1e-46 156.3 0.1 9.1e-46 156.3 0.1 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EME31407.1 - 0.00033 20.7 0.0 0.0088 16.1 0.0 3.3 4 1 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Oest_recep PF02159.10 EME31407.1 - 0.049 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Oestrogen receptor FUSC_2 PF13515.1 EME31408.1 - 5e-12 45.8 13.5 5e-12 45.8 9.4 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EME31408.1 - 4.5e-07 28.8 10.8 0.0002 20.1 5.2 3.2 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EME31408.1 - 1.1 7.6 20.1 0.02 13.3 3.8 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family IATP PF04568.7 EME31409.1 - 0.00055 19.9 1.9 0.0007 19.5 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TPD52 PF04201.10 EME31409.1 - 0.0048 16.6 0.3 0.006 16.3 0.2 1.3 1 0 0 1 1 1 1 Tumour protein D52 family CRISPR_Cas2 PF09827.4 EME31409.1 - 0.017 15.2 1.1 0.41 10.8 0.1 2.5 1 1 2 3 3 3 0 CRISPR associated protein Cas2 DUF3560 PF12083.3 EME31409.1 - 0.043 13.8 2.5 0.052 13.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) DUF1967 PF09269.6 EME31409.1 - 0.11 12.1 0.2 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) EURL PF06937.6 EME31409.1 - 0.3 10.4 2.3 0.35 10.2 1.6 1.1 1 0 0 1 1 1 0 EURL protein Thioredoxin_4 PF13462.1 EME31410.1 - 5.3e-08 33.0 0.0 7.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EME31410.1 - 0.002 17.6 2.2 0.52 9.8 0.0 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain ScdA_N PF04405.9 EME31410.1 - 0.24 10.8 1.4 3.9 6.9 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) ArfGap PF01412.13 EME31411.1 - 2.5e-32 111.0 0.3 2.5e-32 111.0 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf SNARE PF05739.14 EME31412.1 - 2.8e-18 65.3 4.9 2.8e-18 65.3 3.4 2.4 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.20 EME31412.1 - 1.6e-09 37.8 1.6 1.6e-09 37.8 1.1 3.4 4 0 0 4 4 4 1 Syntaxin YjgP_YjgQ PF03739.9 EME31412.1 - 0.00044 19.1 0.6 0.00086 18.1 0.0 1.5 1 1 0 2 2 2 1 Predicted permease YjgP/YjgQ family Prominin PF05478.6 EME31412.1 - 0.00074 17.1 2.3 0.00074 17.1 1.6 2.0 1 1 0 2 2 2 1 Prominin MCPsignal PF00015.16 EME31412.1 - 0.012 15.1 2.8 0.012 15.1 1.9 3.0 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 EME31412.1 - 0.016 15.2 1.2 0.016 15.2 0.9 3.4 2 2 1 3 3 3 0 Syntaxin-like protein Synaptobrevin PF00957.16 EME31412.1 - 0.065 12.8 0.2 0.065 12.8 0.1 2.8 2 0 0 2 2 2 0 Synaptobrevin DUF4303 PF14136.1 EME31412.1 - 0.15 11.6 3.4 0.6 9.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4303) BMFP PF04380.8 EME31412.1 - 0.18 11.9 0.1 0.18 11.9 0.1 4.6 5 1 1 6 6 6 0 Membrane fusogenic activity PEP-utilisers_N PF05524.8 EME31412.1 - 0.52 10.1 14.2 0.084 12.6 0.4 3.7 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF479 PF04336.7 EME31412.1 - 1 9.5 4.8 0.94 9.6 0.1 3.2 3 1 0 4 4 4 0 Protein of unknown function, DUF479 T2SF PF00482.18 EME31412.1 - 2.3 8.1 5.7 1.6 8.6 0.6 2.9 3 2 0 3 3 3 0 Type II secretion system (T2SS), protein F MDFI PF15316.1 EME31412.1 - 3.5 7.5 4.8 11 6.0 0.0 2.7 2 1 0 3 3 3 0 MyoD family inhibitor Med9 PF07544.8 EME31412.1 - 4.4 7.1 10.3 0.29 10.9 0.8 3.5 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Sec34 PF04136.10 EME31412.1 - 8.7 6.0 10.9 0.39 10.3 0.6 3.1 2 1 2 4 4 4 0 Sec34-like family DnaJ PF00226.26 EME31413.1 - 8e-21 73.5 0.5 1.2e-20 73.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain UCR_UQCRX_QCR9 PF05365.7 EME31413.1 - 0.01 15.4 0.1 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like PMP1_2 PF08114.6 EME31413.1 - 0.2 11.1 0.4 0.44 10.0 0.3 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Tubulin PF00091.20 EME31414.1 - 5.1e-75 252.0 0.0 7.3e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME31414.1 - 1.7e-46 157.3 0.0 2.6e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME31414.1 - 6.5e-07 29.4 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME31414.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 EME31414.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin like ubiquitin PF00240.18 EME31415.1 - 6e-105 342.7 13.4 1.6e-34 117.0 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EME31415.1 - 3.7e-62 205.9 11.1 5e-20 70.9 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME31415.1 - 2.3e-21 75.8 4.8 2e-05 24.7 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME31415.1 - 3e-16 59.5 0.1 0.00091 18.9 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME31415.1 - 2.1e-11 43.6 1.0 0.054 13.3 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME31415.1 - 3.1e-10 40.1 0.2 0.13 12.4 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EME31415.1 - 2.4e-09 36.9 1.6 0.17 11.7 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF2870 PF11069.3 EME31415.1 - 6.7e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 EME31415.1 - 0.00015 21.2 2.2 4.2 6.7 0.0 3.1 1 1 0 3 3 3 3 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 EME31415.1 - 0.00042 20.3 3.8 13 5.9 0.1 4.7 3 3 0 3 3 3 0 FERM N-terminal domain Plexin_cytopl PF08337.7 EME31415.1 - 0.00048 18.5 5.2 2.2 6.5 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 EME31415.1 - 0.00055 19.6 0.7 15 5.4 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain YfmQ PF10787.4 EME31415.1 - 0.00086 18.6 0.3 12 5.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein from bacillus cereus group IGR PF09597.5 EME31415.1 - 0.00089 19.1 0.0 22 5.0 0.0 3.3 3 0 0 3 3 3 0 IGR protein motif CTDII PF01556.13 EME31415.1 - 0.0045 16.8 9.8 1.8 8.5 0.2 3.2 1 1 2 3 3 3 2 DnaJ C terminal domain UN_NPL4 PF11543.3 EME31415.1 - 0.0056 16.9 0.4 38 4.6 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 GABP-alpha PF11620.3 EME31415.1 - 0.01 15.7 1.3 31 4.6 0.0 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 EME31415.1 - 0.02 14.1 0.1 13 5.0 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 EME31415.1 - 0.084 12.8 2.1 67 3.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) YajC PF02699.10 EME31415.1 - 0.12 12.0 4.0 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Preprotein translocase subunit DUF2812 PF11193.3 EME31415.1 - 0.13 12.4 0.0 37 4.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2812) Myosin_N PF02736.14 EME31415.1 - 1.6 8.4 4.9 77 3.0 0.1 3.8 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Sec_GG PF07549.9 EME31415.1 - 2 7.8 5.5 1.8e+02 1.6 0.0 4.6 5 0 0 5 5 5 0 SecD/SecF GG Motif Tubulin PF00091.20 EME31416.1 - 4.8e-72 242.2 0.0 7.6e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME31416.1 - 8.7e-49 164.7 0.1 1.3e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME31416.1 - 3.4e-05 23.8 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME31416.1 - 0.0023 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EME31417.1 - 4.8e-72 242.2 0.0 7.6e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME31417.1 - 8.7e-49 164.7 0.1 1.3e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME31417.1 - 3.4e-05 23.8 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME31417.1 - 0.0023 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DNA_primase_lrg PF04104.9 EME31418.1 - 9.3e-66 221.7 0.8 1.3e-65 221.2 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DivIC PF04977.10 EME31418.1 - 0.18 11.3 2.2 6.6 6.2 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator P4Ha_N PF08336.6 EME31418.1 - 0.7 9.7 5.9 2.8 7.7 0.7 2.8 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PC_rep PF01851.17 EME31419.1 - 3.5e-22 77.3 12.8 6.3e-05 22.9 0.1 8.0 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EME31419.1 - 2.4e-05 24.5 8.4 0.0025 18.0 0.2 4.7 3 3 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EME31419.1 - 0.00034 21.0 7.2 2.9 8.4 0.0 5.7 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.17 EME31419.1 - 0.0072 16.3 0.1 2.2 8.6 0.0 3.4 2 0 0 2 2 2 1 HEAT repeat PC_rep PF01851.17 EME31420.1 - 2.9e-22 77.5 12.8 6.1e-05 23.0 0.1 8.0 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EME31420.1 - 1.9e-05 24.8 8.2 0.0024 18.0 0.2 4.7 3 3 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EME31420.1 - 0.00029 21.2 7.2 2.9 8.5 0.0 5.7 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.17 EME31420.1 - 0.0067 16.4 0.1 2.1 8.6 0.0 3.4 2 0 0 2 2 2 1 HEAT repeat CCDC-167 PF15188.1 EME31420.1 - 0.55 10.2 3.6 9.2 6.2 2.3 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RRM_1 PF00076.17 EME31421.1 - 1.2e-10 40.8 0.0 1.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31421.1 - 5.7e-06 26.0 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31421.1 - 1.9e-05 24.5 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EME31421.1 - 1.2 9.6 10.5 1.5 9.2 7.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.17 EME31422.1 - 6.6e-26 89.7 0.0 8.8e-26 89.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31422.1 - 6e-17 61.3 0.0 8.4e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31422.1 - 8.7e-10 38.2 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EME31422.1 - 1.5 9.3 10.7 2.2 8.8 7.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family eIF-4B PF06273.6 EME31422.1 - 6 5.4 9.1 9.1 4.8 6.3 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Pentapeptide PF00805.17 EME31423.1 - 1.2e-18 65.9 6.9 1.6e-10 39.9 1.1 4.2 2 1 2 4 4 4 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 EME31423.1 - 6e-15 54.8 16.7 1e-07 31.7 0.6 3.3 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.1 EME31423.1 - 2.1e-12 46.6 5.8 1.9e-09 37.1 1.8 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EME31423.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain U-box PF04564.10 EME31424.1 - 0.088 12.7 0.6 4.3 7.3 0.0 2.7 1 1 1 2 2 2 0 U-box domain FBPase PF00316.15 EME31426.1 - 2.6e-127 424.1 0.0 2.9e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase F-box-like PF12937.2 EME31427.1 - 3.3e-05 23.5 0.6 8.9e-05 22.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like DnaJ PF00226.26 EME31428.1 - 1e-16 60.4 0.3 1.8e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain HEAT_2 PF13646.1 EME31428.1 - 5.2e-11 42.6 0.0 8e-07 29.2 0.0 3.0 2 1 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 EME31428.1 - 4.3e-07 29.7 5.1 0.43 11.1 0.0 6.0 7 0 0 7 7 7 2 PBS lyase HEAT-like repeat Amidinotransf PF02274.12 EME31429.1 - 4.4e-47 160.5 0.0 5.5e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase CLASP_N PF12348.3 EME31430.1 - 1.2e-12 47.7 1.9 1.2e-12 47.7 1.3 2.3 2 0 0 2 2 2 1 CLASP N terminal MT-A70 PF05063.9 EME31432.1 - 2.3e-08 33.7 2.5 3.2e-07 30.0 1.8 2.5 1 1 0 1 1 1 1 MT-A70 DUF3136 PF11334.3 EME31432.1 - 0.0069 15.7 0.6 0.081 12.3 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3136) MbeD_MobD PF04899.7 EME31432.1 - 0.025 14.4 0.6 0.061 13.2 0.4 1.7 1 0 0 1 1 1 0 MbeD/MobD like SDA1 PF05285.7 EME31432.1 - 0.3 10.3 5.9 0.43 9.8 4.1 1.1 1 0 0 1 1 1 0 SDA1 SRF-TF PF00319.13 EME31433.1 - 1.2e-23 82.0 0.1 2.3e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Aminotran_1_2 PF00155.16 EME31434.1 - 3.8e-46 157.7 0.0 4.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EME31434.1 - 7.8e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME31434.1 - 0.012 13.9 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EME31434.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.15 EME31434.1 - 0.041 12.4 0.0 0.083 11.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain PAP_fibrillin PF04755.7 EME31435.1 - 2.2e-29 102.6 1.2 3.7e-26 92.0 0.8 2.2 1 1 0 1 1 1 1 PAP_fibrillin zf-RING_2 PF13639.1 EME31436.1 - 5.9e-14 51.6 4.3 9.3e-14 50.9 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME31436.1 - 3.7e-08 33.3 1.1 6.7e-08 32.5 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME31436.1 - 1e-06 28.6 4.9 1.9e-06 27.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31436.1 - 1.3e-05 24.8 2.5 2e-05 24.2 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME31436.1 - 2.7e-05 23.7 3.2 4.6e-05 22.9 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31436.1 - 0.00066 19.2 1.6 0.0013 18.4 1.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME31436.1 - 0.0031 17.3 2.8 0.0056 16.4 2.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EME31436.1 - 0.0069 16.0 0.6 0.018 14.7 0.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.1 EME31436.1 - 0.061 13.0 2.9 0.067 12.9 0.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.9 EME31436.1 - 0.09 12.2 2.2 1.8 8.0 0.3 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EME31436.1 - 0.19 11.6 7.8 0.1 12.4 3.0 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EME31436.1 - 0.36 10.5 2.9 0.81 9.4 2.0 1.6 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EME31436.1 - 0.9 9.5 4.7 3.4 7.7 3.2 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EME31436.1 - 1.5 8.4 4.7 20 4.8 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Tcp11 PF05794.8 EME31437.1 - 3.4e-30 105.1 12.9 6.8e-30 104.1 9.0 1.4 1 0 0 1 1 1 1 T-complex protein 11 Asn_synthase PF00733.16 EME31438.1 - 1.2e-38 133.0 0.0 2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Lectin_leg-like PF03388.8 EME31438.1 - 1.3e-17 63.6 0.0 3.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Legume-like lectin family GATase_7 PF13537.1 EME31438.1 - 7.8e-06 25.6 0.0 3.1e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_3 PF01596.12 EME31438.1 - 0.00089 18.3 0.0 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase ATP_bind_3 PF01171.15 EME31438.1 - 0.081 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 PP-loop family GATase_6 PF13522.1 EME31438.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain KIAA1328 PF15369.1 EME31438.1 - 0.17 11.6 3.8 0.26 11.0 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Dus PF01207.12 EME31439.1 - 1.3e-49 168.7 0.1 1.6e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Dus PF01207.12 EME31440.1 - 1.1e-49 168.9 0.1 1.4e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ABC_membrane_2 PF06472.10 EME31441.1 - 1.9e-56 191.2 8.7 2.6e-56 190.8 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME31441.1 - 9.8e-20 71.2 0.0 2.1e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME31441.1 - 5.3e-13 49.0 8.0 7.1e-13 48.5 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SbmA_BacA PF05992.7 EME31441.1 - 1.9e-11 43.7 9.5 1e-10 41.3 6.6 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family NACHT PF05729.7 EME31441.1 - 0.0043 16.7 0.1 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME31441.1 - 0.0075 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME31441.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME31441.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EME31441.1 - 0.054 12.7 1.3 1.6 7.9 0.1 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME31441.1 - 0.089 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME31441.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.1 EME31441.1 - 0.19 11.6 13.3 0.2 11.5 0.1 3.5 3 1 0 3 3 3 0 AAA domain ABC_membrane_2 PF06472.10 EME31442.1 - 1.9e-56 191.2 8.7 2.6e-56 190.8 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME31442.1 - 9.8e-20 71.2 0.0 2.1e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME31442.1 - 5.3e-13 49.0 8.0 7.1e-13 48.5 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SbmA_BacA PF05992.7 EME31442.1 - 1.9e-11 43.7 9.5 1e-10 41.3 6.6 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family NACHT PF05729.7 EME31442.1 - 0.0043 16.7 0.1 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME31442.1 - 0.0075 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME31442.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME31442.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EME31442.1 - 0.054 12.7 1.3 1.6 7.9 0.1 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME31442.1 - 0.089 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME31442.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.1 EME31442.1 - 0.19 11.6 13.3 0.2 11.5 0.1 3.5 3 1 0 3 3 3 0 AAA domain Vps5 PF09325.5 EME31443.1 - 7.1e-08 31.9 8.1 7.1e-08 31.9 5.6 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EME31443.1 - 1.8e-07 30.9 0.2 2.6e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 PX domain DUF2408 PF10303.4 EME31443.1 - 0.013 15.6 3.5 0.18 11.8 2.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4187 PF13821.1 EME31443.1 - 0.059 12.9 0.0 0.22 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) PX PF00787.19 EME31444.1 - 1.4e-07 31.2 0.2 2.3e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EME31444.1 - 5.7e-05 22.4 5.1 5.7e-05 22.4 3.6 1.6 2 0 0 2 2 2 1 Vps5 C terminal like DUF4187 PF13821.1 EME31444.1 - 0.052 13.1 0.0 0.2 11.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF2408 PF10303.4 EME31444.1 - 0.073 13.1 3.3 1.3 9.1 2.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Glyco_transf_5 PF08323.6 EME31445.1 - 2.1e-33 115.8 0.0 3.8e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EME31445.1 - 2.4e-12 46.5 0.0 5.2e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EME31445.1 - 0.011 15.1 0.0 0.36 10.1 0.0 2.2 1 1 0 1 1 1 0 Alpha amylase, catalytic domain WD40 PF00400.27 EME31446.1 - 6.2e-16 57.5 4.5 0.0011 18.7 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ASFV_J13L PF05568.6 EME31446.1 - 0.46 10.0 1.6 0.74 9.3 1.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein U3_snoRNA_assoc PF08297.6 EME31447.1 - 0.053 13.7 16.6 2 8.7 11.5 2.3 1 1 0 1 1 1 0 U3 snoRNA associated LuxC PF05893.9 EME31447.1 - 0.088 11.5 3.7 0.1 11.3 2.6 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) NRDE PF05742.7 EME31447.1 - 0.19 11.0 3.6 0.25 10.5 2.5 1.2 1 0 0 1 1 1 0 NRDE protein His_Phos_2 PF00328.17 EME31447.1 - 0.23 10.7 8.3 0.27 10.5 5.3 1.2 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PGC7_Stella PF15549.1 EME31447.1 - 0.24 11.3 7.6 0.45 10.4 5.3 1.6 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF2317 PF10079.4 EME31447.1 - 0.61 8.6 9.5 0.72 8.3 6.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) IncA PF04156.9 EME31447.1 - 1.2 8.7 8.8 1.4 8.5 6.1 1.3 1 0 0 1 1 1 0 IncA protein BTV_NS2 PF04514.7 EME31447.1 - 1.4 7.7 14.7 1.8 7.3 10.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3246 PF11596.3 EME31447.1 - 1.8 7.8 7.4 1.8 7.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) DUF4304 PF14137.1 EME31447.1 - 3.3 7.8 6.3 0.53 10.4 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4304) OmpH PF03938.9 EME31447.1 - 7.5 6.4 15.1 10 6.0 10.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L7Ae PF01248.21 EME31448.1 - 5.1e-11 41.9 0.4 1.1e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_41 PF13844.1 EME31449.1 - 1.4e-126 422.2 2.1 8e-67 225.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EME31449.1 - 3.2e-29 100.3 22.7 8e-09 35.0 1.1 5.5 3 1 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 EME31449.1 - 8.5e-27 91.6 14.7 7.6e-07 28.4 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EME31449.1 - 1e-23 81.2 15.2 1.7e-05 24.3 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME31449.1 - 1.4e-20 73.0 19.1 4.5e-07 29.7 1.2 4.5 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME31449.1 - 3.2e-20 70.3 0.2 9e-05 21.9 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EME31449.1 - 5.1e-18 63.6 12.1 0.001 19.1 0.3 6.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EME31449.1 - 1.1e-15 56.1 6.1 0.0043 16.7 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EME31449.1 - 1.3e-12 48.0 12.0 0.00041 20.9 2.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME31449.1 - 2.8e-12 46.1 16.9 0.0011 18.8 0.0 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME31449.1 - 6.9e-11 41.7 6.6 0.0031 18.0 0.0 5.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME31449.1 - 0.00016 21.4 8.9 0.1 12.4 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME31449.1 - 0.00023 21.4 6.6 0.13 12.6 0.6 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 EME31449.1 - 0.021 14.0 3.0 1.4 8.0 0.1 2.7 2 1 0 3 3 3 0 Est1 DNA/RNA binding domain TPR_6 PF13174.1 EME31449.1 - 0.068 13.6 2.3 24 5.6 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.1 EME31449.1 - 0.19 10.8 2.0 3.9 6.5 0.2 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP WD40 PF00400.27 EME31450.1 - 3.8e-55 181.8 18.3 7e-08 32.0 0.0 10.6 11 0 0 11 11 11 8 WD domain, G-beta repeat Nup160 PF11715.3 EME31450.1 - 0.0004 18.6 3.6 0.083 11.0 0.0 3.9 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Utp12 PF04003.7 EME31450.1 - 0.0021 17.9 0.3 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 Dip2/Utp12 Family DUF3479 PF11965.3 EME31450.1 - 0.043 13.6 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Mob1_phocein PF03637.12 EME31451.1 - 5.8e-46 156.3 0.0 7.4e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family zf-RING_2 PF13639.1 EME31452.1 - 1.4e-10 40.8 3.2 2.7e-10 39.9 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME31452.1 - 2e-07 31.0 2.0 4.1e-07 30.0 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME31452.1 - 4.7e-06 26.1 2.7 9e-06 25.2 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31452.1 - 6.4e-06 26.0 3.4 1.2e-05 25.2 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31452.1 - 3.2e-05 23.5 1.5 6.1e-05 22.6 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME31452.1 - 4.7e-05 23.1 0.5 9.9e-05 22.1 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME31452.1 - 0.0021 17.7 1.9 0.0042 16.7 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME31452.1 - 0.0095 15.6 3.9 0.035 13.8 0.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EME31452.1 - 2.1 8.3 6.1 12 5.9 4.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain EmrE PF13536.1 EME31453.1 - 0.014 15.5 1.2 0.024 14.8 0.8 1.3 1 0 0 1 1 1 0 Multidrug resistance efflux transporter TPT PF03151.11 EME31454.1 - 5.4e-09 35.8 6.8 5.4e-09 35.8 4.7 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME31454.1 - 4.9e-06 26.6 9.1 4.9e-06 26.6 6.3 3.1 2 2 0 2 2 2 1 EamA-like transporter family DUF3312 PF11768.3 EME31454.1 - 0.0031 15.8 0.1 0.0045 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) SieB PF14163.1 EME31454.1 - 0.023 14.3 0.2 0.023 14.3 0.1 2.3 2 0 0 2 2 2 0 Superinfection exclusion protein B EmrE PF13536.1 EME31454.1 - 5.1 7.3 26.4 4.9 7.3 7.0 3.7 2 2 1 3 3 3 0 Multidrug resistance efflux transporter Mito_carr PF00153.22 EME31455.1 - 1.3e-75 249.2 6.6 9e-25 86.2 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Diphthamide_syn PF01866.12 EME31456.1 - 7.1e-108 360.4 0.0 8.5e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PPTA PF01239.17 EME31457.1 - 8.5e-35 116.6 25.6 7.1e-10 37.8 0.2 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF2363 PF10155.4 EME31457.1 - 0.082 12.8 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) PPTA PF01239.17 EME31458.1 - 3.1e-35 118.0 25.6 5.7e-10 38.0 0.2 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF2363 PF10155.4 EME31458.1 - 0.06 13.2 0.2 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) tRNA-synt_2d PF01409.15 EME31459.1 - 4.8e-52 176.6 0.1 6.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EME31459.1 - 1.8e-05 23.6 1.3 9.5e-05 21.3 0.1 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) S10_plectin PF03501.10 EME31459.1 - 0.023 14.5 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Plectin/S10 domain tRNA-synt_2b PF00587.20 EME31459.1 - 0.036 13.6 0.0 0.046 13.2 0.0 1.3 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) MCD PF05292.6 EME31460.1 - 8.2e-28 97.1 0.0 1.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase (MCD) FBD PF08387.5 EME31460.1 - 0.029 13.8 0.2 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 FBD Grp1_Fun34_YaaH PF01184.14 EME31461.1 - 7e-40 136.5 7.8 9.4e-40 136.1 5.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Topoisom_bac PF01131.15 EME31462.1 - 8.2e-113 377.2 0.1 1.4e-112 376.5 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EME31462.1 - 7.8e-25 86.7 0.0 1.8e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_C_rpt PF13368.1 EME31462.1 - 8.2e-17 61.4 2.3 1.3e-06 28.7 0.0 5.3 5 0 0 5 5 5 3 Topoisomerase C-terminal repeat Toprim_4 PF13662.1 EME31462.1 - 0.00041 20.2 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Toprim domain DegT_DnrJ_EryC1 PF01041.12 EME31462.1 - 0.037 13.0 0.1 0.56 9.1 0.0 2.3 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Toprim_2 PF13155.1 EME31462.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Toprim-like DEP PF00610.16 EME31462.1 - 0.046 13.4 0.0 5.4 6.8 0.0 3.0 1 1 1 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PS_pyruv_trans PF04230.8 EME31462.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Dimerisation PF08100.6 EME31462.1 - 0.14 11.9 0.4 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Dimerisation domain HTH_IclR PF09339.5 EME31462.1 - 0.2 11.2 0.6 7.7 6.1 0.0 2.9 3 0 0 3 3 3 0 IclR helix-turn-helix domain EphA2_TM PF14575.1 EME31463.1 - 0.081 13.3 0.0 0.098 13.0 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MoaE PF02391.12 EME31464.1 - 1.1e-36 125.1 0.6 1.3e-36 124.9 0.4 1.0 1 0 0 1 1 1 1 MoaE protein VWA_2 PF13519.1 EME31465.1 - 3.5e-16 59.7 0.5 6.5e-16 58.9 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.16 EME31465.1 - 4e-16 58.8 0.0 9.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME31465.1 - 9.1e-09 35.1 0.0 8.3e-07 28.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) VWA PF00092.23 EME31465.1 - 7.1e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.21 EME31465.1 - 5.1e-06 26.0 0.0 1.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EME31465.1 - 0.00018 21.7 0.5 0.006 16.7 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 EME31465.1 - 0.00027 19.8 0.5 0.011 14.5 0.1 3.1 2 1 0 2 2 2 1 MCM2/3/5 family VWA_3 PF13768.1 EME31465.1 - 0.0023 17.6 0.0 0.0055 16.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EME31465.1 - 0.009 15.1 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Sigma54_activ_2 PF14532.1 EME31465.1 - 0.014 15.4 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 EME31465.1 - 0.04 13.9 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EME31465.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME31465.1 - 0.1 12.7 0.4 1.5 8.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain 4HBT_3 PF13622.1 EME31465.1 - 0.12 12.0 0.3 0.33 10.6 0.2 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily ketoacyl-synt PF00109.21 EME31466.1 - 3.1e-56 190.6 0.1 4.6e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EME31466.1 - 1.7e-33 115.0 0.2 3.1e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EME31466.1 - 0.00028 19.9 0.5 0.00053 19.0 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SNARE PF05739.14 EME31467.1 - 6.4e-05 22.5 4.0 0.00014 21.4 2.8 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-18_N PF10496.4 EME31467.1 - 0.00024 20.8 5.7 0.00041 20.1 0.2 3.6 2 1 2 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1320 PF07030.7 EME31467.1 - 0.047 13.4 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) DUF1045 PF06299.7 EME31467.1 - 0.048 13.3 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) DUF3753 PF12575.3 EME31467.1 - 0.093 12.5 0.1 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) zf-C4H2 PF10146.4 EME31467.1 - 8.6 6.3 11.2 2.2 8.2 1.7 2.6 3 1 0 3 3 3 0 Zinc finger-containing protein TRAM_LAG1_CLN8 PF03798.11 EME31468.1 - 2.7e-32 111.9 30.7 3.8e-32 111.4 21.3 1.2 1 0 0 1 1 1 1 TLC domain Pribosyltran_N PF13793.1 EME31469.1 - 9.5e-43 144.6 0.1 8.2e-41 138.3 0.0 2.7 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EME31469.1 - 1.8e-24 86.5 1.3 2.1e-23 83.0 0.1 2.5 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EME31469.1 - 1.3e-14 54.0 0.4 2.1e-13 50.0 0.2 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME31469.1 - 2.4e-06 26.9 0.0 6.5e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EME31469.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase TPR_14 PF13428.1 EME31470.1 - 4.7e-09 36.0 0.1 3.6 8.4 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME31470.1 - 6.5e-09 35.6 1.2 0.34 10.8 0.0 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME31470.1 - 8.1e-09 35.0 10.4 0.14 11.8 0.0 6.7 7 1 1 8 8 8 3 TPR repeat TPR_19 PF14559.1 EME31470.1 - 1.3e-07 31.8 2.5 0.064 13.6 0.0 5.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME31470.1 - 1.7e-07 30.5 1.2 0.16 11.5 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME31470.1 - 1.8e-05 24.2 14.3 0.95 9.5 0.0 7.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME31470.1 - 0.00064 19.3 6.1 0.45 10.4 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 EME31470.1 - 0.0088 15.9 4.1 5.7 7.1 0.0 5.4 6 0 0 6 6 6 1 PPR repeat TPR_16 PF13432.1 EME31470.1 - 0.064 13.9 3.5 48 4.8 0.0 5.8 7 1 0 7 7 7 0 Tetratricopeptide repeat DNA_photolyase PF00875.13 EME31471.1 - 2.6e-21 76.0 0.0 1e-20 74.1 0.0 1.8 1 1 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EME31471.1 - 0.0006 19.1 0.1 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Topoisom_I_N PF02919.10 EME31472.1 - 1.7e-90 302.0 2.9 1.7e-90 302.0 2.0 4.0 3 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EME31472.1 - 5e-88 294.1 1.3 5e-88 294.1 0.9 2.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EME31472.1 - 6.1e-33 112.3 1.6 2.9e-32 110.1 0.3 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain CD47 PF04549.9 EME31473.1 - 0.095 12.7 0.3 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 CD47 transmembrane region NDUFB10 PF10249.4 EME31474.1 - 0.00012 22.2 4.2 0.00016 21.7 2.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 RNA_pol_Rpb1_6 PF04992.9 EME31474.1 - 0.091 12.4 0.8 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Cytochrom_B561 PF03188.11 EME31475.1 - 0.0039 17.0 7.2 0.0039 17.0 5.0 2.2 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 DUF2231 PF09990.4 EME31475.1 - 0.18 12.1 6.7 3.9 7.8 2.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) GP41 PF00517.12 EME31475.1 - 0.93 9.0 7.4 1.5 8.3 3.1 2.1 2 0 0 2 2 2 0 Retroviral envelope protein Amidohydro_2 PF04909.9 EME31476.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase LIP PF03583.9 EME31476.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Sugar_tr PF00083.19 EME31477.1 - 1.4e-46 159.0 2.7 1.7e-46 158.7 1.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31477.1 - 6.3e-23 81.0 9.7 7.7e-23 80.7 6.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME31477.1 - 4.2e-06 25.2 3.0 5.2e-06 24.9 2.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EME31477.1 - 0.00026 20.9 3.9 0.079 12.9 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) Furin-like PF00757.15 EME31478.1 - 1.9e-10 40.5 91.0 0.0085 15.7 13.9 7.8 1 1 5 6 6 6 5 Furin-like cysteine rich region DapB_N PF01113.15 EME31479.1 - 7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DapB_C PF05173.9 EME31479.1 - 4.5e-10 39.4 0.1 9.4e-10 38.3 0.1 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DUF1528 PF07515.6 EME31479.1 - 0.04 13.9 0.3 0.097 12.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1528) Scramblase PF03803.10 EME31480.1 - 4.8e-49 166.4 0.0 6.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Scramblase DUF1183 PF06682.7 EME31480.1 - 0.055 13.0 0.3 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) JAB PF01398.16 EME31481.1 - 3.1e-17 62.3 0.5 5.9e-17 61.4 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EME31481.1 - 2.6e-08 33.3 0.0 6.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EME31481.1 - 7.3e-07 29.1 0.5 2.1e-06 27.6 0.2 1.9 1 1 1 2 2 2 1 USP8 dimerisation domain JAB PF01398.16 EME31482.1 - 2.2e-17 62.8 0.5 4.3e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EME31482.1 - 1.9e-08 33.7 0.0 4.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EME31482.1 - 5.5e-07 29.5 0.6 1.6e-06 28.0 0.3 2.0 1 1 1 2 2 2 1 USP8 dimerisation domain Chloroa_b-bind PF00504.16 EME31483.1 - 2.9e-39 134.8 0.0 3.5e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CH PF00307.26 EME31484.1 - 0.0018 18.3 2.0 0.0045 17.0 0.0 2.5 2 1 0 2 2 2 1 Calponin homology (CH) domain bZIP_2 PF07716.10 EME31484.1 - 0.019 14.7 3.0 0.019 14.7 2.1 4.9 5 0 0 5 5 5 0 Basic region leucine zipper Chloroa_b-bind PF00504.16 EME31485.1 - 7.6e-41 139.9 0.0 1.2e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2955 PF11168.3 EME31485.1 - 0.027 14.1 0.4 0.047 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) AA_permease PF00324.16 EME31485.1 - 0.084 11.1 0.3 0.16 10.2 0.2 1.4 1 1 0 1 1 1 0 Amino acid permease DUF2201_N PF13203.1 EME31485.1 - 0.49 9.5 4.1 0.62 9.1 2.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF936 PF06075.7 EME31485.1 - 0.66 8.8 13.1 0.82 8.5 9.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ASFV_J13L PF05568.6 EME31485.1 - 0.7 9.3 4.0 0.59 9.6 0.9 1.9 1 1 1 2 2 2 0 African swine fever virus J13L protein MARVEL PF01284.18 EME31488.1 - 0.00013 21.8 11.9 0.00024 20.9 8.2 1.6 1 1 0 1 1 1 1 Membrane-associating domain Synaptobrevin PF00957.16 EME31489.1 - 3.3e-30 103.5 1.6 5.2e-30 102.8 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EME31489.1 - 2.8e-21 74.8 0.1 5.4e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.8 EME31489.1 - 0.00094 18.6 0.3 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal ODV-E18 PF10717.4 EME31489.1 - 0.0012 18.1 0.2 0.0035 16.7 0.2 1.8 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.7 EME31489.1 - 0.01 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EVI2A PF05399.6 EME31489.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) SP_C-Propep PF08999.5 EME31489.1 - 0.02 14.3 0.2 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ETRAMP PF09716.5 EME31489.1 - 0.026 14.4 0.3 0.049 13.5 0.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Chordopox_A13L PF05961.6 EME31489.1 - 0.032 14.1 2.2 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein SecG PF03840.9 EME31489.1 - 0.033 13.9 2.8 0.085 12.6 1.9 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Baculo_11_kDa PF06143.6 EME31489.1 - 0.052 12.9 0.7 0.12 11.7 0.5 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Herpes_US9 PF06072.6 EME31489.1 - 0.053 13.3 1.8 0.094 12.5 1.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF872 PF05915.7 EME31489.1 - 0.076 12.8 0.1 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Fe_bilin_red PF05996.7 EME31489.1 - 0.081 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase Prominin PF05478.6 EME31489.1 - 0.085 10.3 7.4 0.57 7.6 1.4 2.1 1 1 1 2 2 2 0 Prominin COX4_pro_2 PF07835.7 EME31489.1 - 0.74 9.8 4.5 1.3 9.0 3.1 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Sec1 PF00995.18 EME31490.1 - 1.1e-112 377.6 0.1 1.5e-112 377.1 0.1 1.2 1 0 0 1 1 1 1 Sec1 family VSP PF03302.8 EME31490.1 - 0.00014 20.6 0.2 0.00025 19.7 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF2833 PF11090.3 EME31492.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Dopey_N PF04118.9 EME31493.1 - 3.3e-72 242.8 4.8 8e-72 241.6 3.3 1.7 1 0 0 1 1 1 1 Dopey, N-terminal HEAT PF02985.17 EME31493.1 - 0.0057 16.6 0.3 0.27 11.4 0.1 3.3 2 0 0 2 2 2 1 HEAT repeat CHZ PF09649.5 EME31494.1 - 0.00067 18.8 0.1 0.0026 16.9 0.1 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ TFIID_20kDa PF03847.8 EME31494.1 - 0.073 13.3 1.4 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Mlf1IP PF10248.4 EME31495.1 - 1.3e-07 31.3 1.7 2.7e-07 30.3 1.2 1.5 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein CM2 PF03021.9 EME31495.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein BRK PF07533.11 EME31496.1 - 2.9e-07 29.8 0.1 0.005 16.2 0.1 2.6 2 0 0 2 2 2 2 BRK domain Img2 PF05046.9 EME31496.1 - 0.027 14.7 0.0 9 6.6 0.0 2.9 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Complex1_LYR_1 PF13232.1 EME31497.1 - 0.13 12.5 0.2 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Complex1_LYR-like Oligomerisation PF02410.10 EME31498.1 - 2.6e-22 78.7 0.1 7.2e-22 77.3 0.0 1.7 2 0 0 2 2 2 1 Oligomerisation domain Gly_acyl_tr_N PF06021.6 EME31500.1 - 0.059 12.7 0.0 0.068 12.5 0.0 1.0 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase COX6A PF02046.10 EME31501.1 - 0.00011 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Abhydrolase_6 PF12697.2 EME31502.1 - 2.4e-19 70.1 0.1 1.2e-18 67.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME31502.1 - 2e-13 50.2 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME31502.1 - 7.6e-07 28.9 0.0 1.1e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME31502.1 - 5e-05 22.6 0.0 0.00015 21.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME31502.1 - 0.00042 19.8 0.0 0.0062 16.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EME31502.1 - 0.082 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ras PF00071.17 EME31503.1 - 5.6e-64 214.3 0.7 6.7e-64 214.1 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME31503.1 - 2.1e-21 76.5 0.1 3.4e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME31503.1 - 1.5e-14 53.6 0.1 1.9e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME31503.1 - 5e-07 29.6 0.1 7.9e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME31503.1 - 5.8e-06 25.8 0.2 1.8e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EME31503.1 - 1.7e-05 24.0 1.0 2.2e-05 23.6 0.7 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME31503.1 - 0.00038 20.6 0.2 0.0013 18.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EME31503.1 - 0.00064 18.9 0.2 0.001 18.2 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EME31503.1 - 0.0018 18.1 0.1 0.0041 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME31503.1 - 0.0026 16.9 0.1 0.0063 15.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EME31503.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation EcoRI PF02963.11 EME31503.1 - 0.0073 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease EcoRI SRPRB PF09439.5 EME31503.1 - 0.0085 15.3 0.2 0.021 14.0 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EME31503.1 - 0.017 15.4 0.1 0.029 14.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EME31503.1 - 0.019 14.9 0.2 0.092 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EME31503.1 - 0.028 14.1 0.2 0.055 13.1 0.2 1.5 1 1 0 1 1 1 0 NTPase FeoB_N PF02421.13 EME31503.1 - 0.043 13.0 0.2 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 EME31503.1 - 0.085 11.8 0.1 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 EME31503.1 - 0.089 12.3 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.6 EME31503.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_21 PF13304.1 EME31503.1 - 0.18 11.7 1.0 0.29 11.0 0.6 1.5 1 1 0 1 1 1 0 AAA domain Pribosyltran_N PF13793.1 EME31504.1 - 5.9e-51 171.0 0.1 6.5e-47 158.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EME31504.1 - 1.5e-24 86.7 1.4 2.1e-23 83.0 0.3 2.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EME31504.1 - 8.8e-16 57.7 3.6 1.2e-15 57.3 0.4 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME31504.1 - 0.00011 21.4 0.1 0.00019 20.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PolyA_pol_RNAbd PF12627.2 EME31504.1 - 0.16 11.5 0.5 0.65 9.6 0.1 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A ERO1 PF04137.10 EME31505.1 - 1.4e-112 376.2 0.7 1.8e-112 375.9 0.5 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Taxilin PF09728.4 EME31506.1 - 1.4e-37 129.4 57.6 1.4e-37 129.4 39.9 2.0 1 1 1 2 2 2 1 Myosin-like coiled-coil protein Tropomyosin PF00261.15 EME31506.1 - 0.00019 20.5 12.0 0.00019 20.5 8.3 3.5 2 1 1 3 3 3 1 Tropomyosin TMF_DNA_bd PF12329.3 EME31506.1 - 0.0067 16.2 7.3 0.0067 16.2 5.0 6.9 3 3 4 7 7 6 2 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 EME31506.1 - 0.013 14.9 2.1 0.013 14.9 1.4 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2968) Cortex-I_coil PF09304.5 EME31506.1 - 0.013 15.5 7.0 0.013 15.5 4.8 4.8 3 2 1 4 4 4 0 Cortexillin I, coiled coil MxiH PF09392.5 EME31506.1 - 0.027 15.0 7.3 0.033 14.7 1.1 3.4 2 2 0 2 2 2 0 Type III secretion needle MxiH like Reo_sigmaC PF04582.7 EME31506.1 - 0.041 13.0 6.1 0.099 11.8 1.9 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF4250 PF14056.1 EME31506.1 - 0.34 10.6 0.0 0.34 10.6 0.0 4.0 5 1 1 6 6 5 0 Domain of unknown function (DUF4250) FIVAR PF07554.8 EME31506.1 - 0.35 11.1 4.3 0.17 12.1 0.6 2.4 2 0 0 2 2 1 0 Uncharacterised Sugar-binding Domain DUF948 PF06103.6 EME31506.1 - 1.3 8.9 13.1 21 5.0 0.0 4.2 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EME31506.1 - 3.2 6.1 50.0 0.37 9.2 15.0 2.6 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 EME31506.1 - 5.4 7.3 10.5 20 5.5 0.5 4.8 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EME31506.1 - 8.2 6.1 58.8 0.025 14.3 9.5 4.1 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Activator-TraM PF11657.3 EME31506.1 - 8.5 5.8 19.1 4.4 6.7 1.1 3.5 3 1 1 4 4 4 0 Transcriptional activator TraM HNH PF01844.18 EME31507.1 - 6.4e-08 32.3 0.7 6.4e-08 32.3 0.5 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.1 EME31507.1 - 0.00046 19.7 0.0 0.0025 17.4 0.0 2.1 3 0 0 3 3 3 1 HNH endonuclease TGT PF01702.13 EME31508.1 - 2.3e-47 161.3 0.5 2.9e-47 160.9 0.4 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TGT PF01702.13 EME31509.1 - 1.4e-48 165.2 0.5 1.9e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase GHMP_kinases_N PF00288.21 EME31510.1 - 2.1e-06 27.6 0.3 4e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_N PF00288.21 EME31511.1 - 2e-06 27.7 0.3 3.7e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain EamA PF00892.15 EME31513.1 - 1.2e-13 51.1 10.6 3.1e-10 40.1 0.7 4.1 4 0 0 4 4 4 2 EamA-like transporter family Metallophos PF00149.23 EME31513.1 - 3.1e-05 23.4 0.1 0.00011 21.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EmrE PF13536.1 EME31513.1 - 0.00017 21.7 2.6 0.00017 21.7 1.8 3.4 3 1 0 3 3 3 2 Multidrug resistance efflux transporter RabGAP-TBC PF00566.13 EME31514.1 - 2.2e-30 105.7 5.4 3.1e-30 105.2 3.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DAP3 PF10236.4 EME31515.1 - 5.1e-29 101.1 0.0 1e-28 100.2 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 EME31515.1 - 0.0016 18.1 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EME31515.1 - 0.029 13.8 0.0 0.58 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EME31515.1 - 0.037 14.1 0.0 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain CH PF00307.26 EME31515.1 - 0.09 12.8 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain WD40 PF00400.27 EME31516.1 - 4.1e-66 216.6 27.2 7.6e-11 41.4 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EME31516.1 - 6.6e-11 41.2 3.5 1.3e-10 40.3 2.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EME31516.1 - 1.2e-07 31.5 0.1 0.024 14.3 0.0 3.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME31516.1 - 5.6e-05 21.4 11.6 0.32 9.0 0.1 4.7 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME31516.1 - 0.00031 19.5 2.2 0.0036 16.1 0.1 2.7 1 1 2 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EME31516.1 - 0.012 13.9 0.0 0.14 10.4 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain DEAD PF00270.24 EME31517.1 - 1.7e-50 170.8 0.0 5.2e-50 169.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31517.1 - 1.3e-30 105.0 0.0 3.2e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME31517.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1604 PF07713.8 EME31518.1 - 1.4e-27 95.2 0.3 1.4e-27 95.2 0.2 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EME31518.1 - 0.088 12.6 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 G-patch domain Cut8_N PF14482.1 EME31518.1 - 1.1 9.2 13.0 0.068 13.1 0.9 3.6 3 1 0 3 3 3 0 Cut8 proteasome-binding domain DUF974 PF06159.8 EME31519.1 - 3e-13 49.8 0.0 5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 EME31519.1 - 1.9e-09 37.3 3.3 4.8e-05 22.8 0.0 3.7 3 1 0 4 4 4 3 TRAPP trafficking subunit Trs65 Transglut_C PF00927.17 EME31519.1 - 0.087 12.8 0.2 2.4 8.2 0.0 3.1 3 1 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain Mcm10 PF09332.6 EME31520.1 - 0.074 12.3 9.3 0.081 12.2 6.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor SOBP PF15279.1 EME31520.1 - 2 8.6 17.5 2.7 8.3 12.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein VirE2 PF07229.7 EME31520.1 - 2.2 6.5 7.1 3 6.1 4.9 1.1 1 0 0 1 1 1 0 VirE2 DUF4407 PF14362.1 EME31520.1 - 3.8 6.3 6.9 4.9 6.0 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1675 PF07897.6 EME31520.1 - 7.7 6.2 14.4 13 5.5 10.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) PfkB PF00294.19 EME31521.1 - 1.2e-58 198.6 0.0 1.4e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EME31521.1 - 0.0067 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Thioredoxin PF00085.15 EME31522.1 - 1.5e-64 214.2 0.6 1.7e-32 111.1 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EME31522.1 - 1.9e-19 70.0 3.7 3.1e-19 69.4 1.5 2.1 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EME31522.1 - 4.7e-19 68.6 0.3 7.2e-08 32.6 0.1 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME31522.1 - 2.5e-14 53.0 0.1 3.3e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EME31522.1 - 1.7e-13 50.5 0.1 7.6e-05 22.7 0.0 3.8 2 2 2 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.1 EME31522.1 - 4e-10 39.7 3.7 1.1e-09 38.4 0.9 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EME31522.1 - 1.7e-08 34.1 0.1 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EME31522.1 - 5.5e-08 32.4 0.1 0.0051 16.3 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 EME31522.1 - 3e-06 27.1 0.8 0.0055 16.6 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EME31522.1 - 2.1e-05 24.5 1.3 0.77 9.7 0.1 3.7 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 EME31522.1 - 0.0085 15.6 0.3 4.3 6.9 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin DSBA PF01323.15 EME31522.1 - 0.017 14.6 1.2 13 5.2 0.0 3.5 2 2 2 4 4 4 0 DSBA-like thioredoxin domain HyaE PF07449.6 EME31522.1 - 0.019 14.8 0.0 8 6.4 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.1 EME31522.1 - 0.041 14.0 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain Glyco_transf_8 PF01501.15 EME31524.1 - 5.2e-22 78.4 0.0 3.3e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 GIY-YIG PF01541.19 EME31525.1 - 4.7e-05 23.6 0.1 0.00013 22.2 0.0 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain GIY-YIG PF01541.19 EME31526.1 - 7e-05 23.1 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain bZIP_1 PF00170.16 EME31527.1 - 0.021 14.7 14.1 0.021 14.7 9.7 2.0 1 1 1 2 2 2 0 bZIP transcription factor DUF1886 PF09171.5 EME31527.1 - 0.33 9.9 4.4 0.49 9.3 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) bZIP_Maf PF03131.12 EME31527.1 - 0.86 9.9 22.0 0.16 12.2 11.2 2.6 2 1 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EME31527.1 - 2.4 8.0 20.0 1.5 8.7 11.9 2.2 1 1 1 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EME31527.1 - 2.5 7.6 14.4 0.11 12.1 4.9 2.0 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EME31527.1 - 3.6 7.7 11.4 6.8 6.8 5.5 2.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Cut12 PF11500.3 EME31527.1 - 7.1 6.3 9.3 4 7.1 4.0 2.0 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Epimerase_Csub PF13950.1 EME31528.1 - 4.1e-31 106.7 0.1 7.2e-31 105.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 EME31528.1 - 1.9e-23 83.1 0.0 2.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME31528.1 - 0.049 12.5 0.0 0.09 11.6 0.0 1.3 2 0 0 2 2 2 0 RmlD substrate binding domain CCT PF06203.9 EME31529.1 - 2.1e-15 56.0 12.2 5.9e-15 54.6 8.5 1.8 1 0 0 1 1 1 1 CCT motif UPF0160 PF03690.8 EME31530.1 - 3.4e-127 424.2 0.0 4e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GFA PF04828.9 EME31532.1 - 1.4e-08 34.5 2.2 1.4e-08 34.5 1.5 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Carb_anhydrase PF00194.16 EME31534.1 - 4.7e-19 68.3 0.0 4.1e-18 65.2 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EME31535.1 - 1.1e-13 50.7 0.1 4.7e-06 25.7 0.1 3.2 3 1 0 3 3 3 2 Eukaryotic-type carbonic anhydrase RRF PF01765.14 EME31536.1 - 3.4e-29 101.4 0.4 2.5e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 Ribosome recycling factor DUF4094 PF13334.1 EME31536.1 - 0.0098 16.2 0.9 0.018 15.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) TRSP PF12500.3 EME31536.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 zf-AN1 PF01428.11 EME31537.1 - 1.9e-11 43.6 9.6 1.9e-11 43.6 6.6 2.0 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EME31537.1 - 4.6e-10 38.8 4.4 1.5e-09 37.2 3.1 2.0 1 0 0 1 1 1 1 A20-like zinc finger Activator_LAG-3 PF11498.3 EME31537.1 - 0.0035 16.1 6.9 0.0041 15.9 4.8 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 RPAP2_Rtr1 PF04181.8 EME31537.1 - 0.085 12.9 0.9 0.085 12.9 0.6 3.0 2 1 0 2 2 2 0 Rtr1/RPAP2 family DUF4647 PF15504.1 EME31537.1 - 0.18 10.6 6.7 0.21 10.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) zf-RING_4 PF14570.1 EME31537.1 - 8.7 6.0 12.6 7.9 6.1 3.6 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CP12 PF02672.10 EME31538.1 - 0.0011 19.4 0.1 2.2 8.8 0.0 2.3 2 0 0 2 2 2 2 CP12 domain ING PF12998.2 EME31538.1 - 0.043 14.0 2.0 0.043 14.0 1.4 2.0 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Adeno_E1B_19K PF01691.11 EME31538.1 - 0.11 11.7 0.4 0.25 10.6 0.0 1.7 2 1 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen IncA PF04156.9 EME31538.1 - 4.4 6.8 11.5 1.3 8.5 1.9 2.0 1 1 1 2 2 2 0 IncA protein DUF1995 PF09353.5 EME31539.1 - 8.9e-22 77.7 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF494 PF04361.8 EME31540.1 - 0.024 14.3 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Init_tRNA_PT PF04179.7 EME31541.1 - 2e-83 280.7 0.0 4.3e-83 279.6 0.0 1.5 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase SOR_SNZ PF01680.12 EME31542.1 - 1.8e-114 380.5 4.7 2.7e-114 379.9 3.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EME31542.1 - 1.1e-08 34.4 4.4 2.8e-06 26.5 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 EME31542.1 - 0.00015 20.8 2.0 0.014 14.3 0.0 3.1 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EME31542.1 - 0.0004 19.3 0.8 0.64 8.7 0.1 2.6 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EME31542.1 - 0.0022 17.2 1.0 0.068 12.4 0.0 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EME31542.1 - 0.0027 16.7 0.1 0.038 13.0 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 EME31542.1 - 0.016 14.3 0.3 0.016 14.3 0.2 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase Baculo_p26 PF04766.7 EME31543.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus p26 protein GIIM PF08388.6 EME31543.1 - 0.042 13.6 1.6 5.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Group II intron, maturase-specific domain WD40 PF00400.27 EME31544.1 - 2.5e-06 27.1 2.3 0.0065 16.3 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Nup160 PF11715.3 EME31544.1 - 0.0053 14.9 1.0 0.36 8.9 0.7 2.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EME31545.1 - 2.5e-06 27.1 2.3 0.0065 16.3 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Nup160 PF11715.3 EME31545.1 - 0.0053 14.9 1.0 0.36 8.9 0.7 2.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Archease PF01951.11 EME31546.1 - 6e-26 91.0 0.0 8.2e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) HTH_3 PF01381.17 EME31547.1 - 1e-15 57.2 0.4 2e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 EME31547.1 - 1.5e-09 37.7 0.5 1.5e-09 37.7 0.4 2.3 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.1 EME31547.1 - 3.8e-09 36.5 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EME31547.1 - 5e-09 36.0 0.1 7.6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 EME31547.1 - 0.0025 17.6 0.4 0.0035 17.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EME31547.1 - 0.036 14.2 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.1 EME31547.1 - 0.077 12.3 0.3 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding IPPT PF01715.12 EME31548.1 - 6.7e-63 212.0 0.0 1.2e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 EME31548.1 - 4e-10 39.2 0.0 1.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EME31548.1 - 3.5e-09 37.5 1.0 8.8e-08 32.9 0.6 2.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME31548.1 - 1.2e-05 24.5 0.0 0.00036 19.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EME31548.1 - 0.00018 21.8 0.3 0.00053 20.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain PPV_E1_C PF00519.12 EME31548.1 - 0.00028 19.6 0.1 0.00059 18.5 0.0 1.5 1 0 0 1 1 1 1 Papillomavirus helicase AAA_33 PF13671.1 EME31548.1 - 0.00051 19.9 0.4 0.028 14.3 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EME31548.1 - 0.0043 17.1 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EME31548.1 - 0.0092 15.8 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EME31548.1 - 0.011 15.7 0.0 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EME31548.1 - 0.024 14.9 0.1 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EME31548.1 - 0.031 12.9 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CbiA PF01656.18 EME31548.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 EME31548.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EME31548.1 - 0.055 13.2 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SKI PF01202.17 EME31548.1 - 0.066 13.0 0.1 0.62 9.9 0.0 2.5 2 1 0 2 2 2 0 Shikimate kinase PRK PF00485.13 EME31548.1 - 0.082 12.4 0.1 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 EME31548.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EME31548.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EME31548.1 - 0.12 11.2 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EME31548.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME31548.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IPPT PF01715.12 EME31549.1 - 5.6e-63 212.3 0.0 1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 EME31549.1 - 3.3e-10 39.5 0.0 1.3e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EME31549.1 - 3.3e-09 37.5 1.1 7.7e-08 33.1 0.8 2.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME31549.1 - 1.1e-05 24.6 0.0 0.00032 19.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EME31549.1 - 0.00017 21.9 0.3 0.00047 20.4 0.0 2.0 2 1 1 3 3 1 1 AAA domain PPV_E1_C PF00519.12 EME31549.1 - 0.00026 19.7 0.1 0.00053 18.7 0.0 1.4 1 0 0 1 1 1 1 Papillomavirus helicase AAA_33 PF13671.1 EME31549.1 - 0.00046 20.0 0.6 0.025 14.4 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EME31549.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EME31549.1 - 0.0093 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EME31549.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 EME31549.1 - 0.03 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EME31549.1 - 0.032 14.5 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EME31549.1 - 0.034 13.5 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 EME31549.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EME31549.1 - 0.049 13.3 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SKI PF01202.17 EME31549.1 - 0.055 13.3 0.1 0.55 10.0 0.0 2.5 2 1 0 2 2 2 0 Shikimate kinase PRK PF00485.13 EME31549.1 - 0.075 12.5 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 EME31549.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EME31549.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME31549.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EME31549.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EME31549.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Pam16 PF03656.8 EME31550.1 - 3.1e-11 43.1 0.8 7.3e-11 41.9 0.6 1.5 1 1 0 1 1 1 1 Pam16 CAF1 PF04857.15 EME31552.1 - 2.1e-44 151.8 0.0 2.8e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EME31552.1 - 0.045 13.2 0.0 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease DUF525 PF04379.9 EME31553.1 - 5.9e-25 87.0 0.0 2.1e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF525) F-box-like PF12937.2 EME31553.1 - 2e-12 46.5 0.3 2e-12 46.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME31553.1 - 2.2e-09 36.7 0.1 2.2e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain DUF3134 PF11332.3 EME31555.1 - 0.077 13.1 7.4 0.081 13.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) Phage_Gp23 PF10669.4 EME31555.1 - 0.15 12.1 0.3 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PTPLA PF04387.9 EME31556.1 - 1.1e-56 190.7 7.0 1.5e-56 190.3 4.9 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_trans_1_4 PF13692.1 EME31557.1 - 2.3e-16 60.1 0.0 6.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EME31557.1 - 6.8e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME31557.1 - 2.9e-05 24.2 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PCI PF01399.22 EME31558.1 - 5.4e-16 58.8 1.7 1.7e-15 57.2 0.0 2.5 3 0 0 3 3 3 1 PCI domain Glyco_transf_49 PF13896.1 EME31559.1 - 3.2e-20 72.4 1.2 2e-18 66.5 0.5 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EME31559.1 - 0.00017 20.8 0.4 0.00028 20.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME31559.1 - 0.0087 15.7 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Pro_isomerase PF00160.16 EME31560.1 - 6.9e-28 97.8 0.2 7.8e-28 97.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-TFIIIC PF12660.2 EME31561.1 - 7.4e-08 32.2 2.6 2.5e-07 30.5 1.8 1.9 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WD40 PF00400.27 EME31561.1 - 2.2e-07 30.4 2.6 1e-05 25.1 0.7 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat PAH PF02671.16 EME31562.1 - 0.15 11.7 0.2 0.62 9.7 0.1 2.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat F-box PF00646.28 EME31563.1 - 5.5e-06 25.9 0.1 8.7e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME31563.1 - 0.0013 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 F-box-like TFCD_C PF12612.3 EME31564.1 - 3.8e-13 49.2 2.7 3.6e-12 46.1 0.5 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EME31564.1 - 2.8e-11 43.5 0.1 0.0045 17.2 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EME31564.1 - 2.8e-08 33.9 4.7 0.15 12.5 0.0 7.1 6 2 2 8 8 8 3 HEAT-like repeat HEAT PF02985.17 EME31564.1 - 5e-07 29.2 16.9 0.024 14.7 0.0 8.0 9 0 0 9 9 9 2 HEAT repeat Arm PF00514.18 EME31564.1 - 0.0052 16.5 0.8 0.66 9.8 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EME31564.1 - 0.65 10.6 6.3 66 4.4 0.0 5.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat zf-C3HC4_3 PF13920.1 EME31565.1 - 2.9e-17 62.0 10.5 5.5e-17 61.1 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31565.1 - 6.6e-09 35.6 13.3 1.8e-08 34.2 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME31565.1 - 1.7e-05 24.5 13.3 1.7e-05 24.5 9.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME31565.1 - 0.0002 20.9 12.3 0.00045 19.8 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.9 EME31565.1 - 0.24 10.9 14.6 0.028 13.8 5.5 2.3 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_4 PF14447.1 EME31565.1 - 0.48 10.0 8.5 1 8.9 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 P5CR_dimer PF14748.1 EME31566.1 - 7.1e-43 144.9 0.2 1.2e-42 144.2 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EME31566.1 - 1.9e-13 50.6 0.1 4.8e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EME31566.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_23 PF13489.1 EME31567.1 - 1.7e-13 50.6 0.1 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME31567.1 - 4.8e-13 49.4 0.0 8.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME31567.1 - 2.8e-11 43.2 0.0 3.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME31567.1 - 3.4e-09 37.2 0.0 6.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME31567.1 - 2.3e-08 34.3 0.0 5.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31567.1 - 2.1e-07 31.3 0.0 4.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME31567.1 - 0.00051 20.0 0.0 0.0021 18.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME31567.1 - 0.00051 19.4 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 EME31567.1 - 0.0024 16.6 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) FmrO PF07091.6 EME31567.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) NNMT_PNMT_TEMT PF01234.12 EME31567.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.6 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family FPL PF09758.4 EME31568.1 - 4.1e-10 39.6 6.3 5.6e-10 39.1 0.3 3.0 2 1 0 2 2 2 1 Uncharacterised conserved protein Propep_M14 PF02244.11 EME31568.1 - 0.059 13.0 0.3 19 5.0 0.0 3.1 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Cadherin_C PF01049.12 EME31569.1 - 0.028 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region Interfer-bind PF09294.5 EME31569.1 - 0.029 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III SNF2_N PF00176.18 EME31570.1 - 3.2e-71 239.5 0.3 7.3e-71 238.3 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EME31570.1 - 3.5e-09 36.3 7.4 3.5e-09 36.3 5.1 3.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME31570.1 - 2.6e-07 30.2 6.0 2.6e-07 30.2 4.2 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME31570.1 - 3.5e-07 30.1 7.7 3.5e-07 30.1 5.3 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME31570.1 - 2.7e-06 26.9 7.8 2.7e-06 26.9 5.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EME31570.1 - 0.00032 20.5 0.1 0.00075 19.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EME31570.1 - 0.00038 20.1 3.8 0.0013 18.4 2.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME31570.1 - 0.0017 18.1 10.3 0.0021 17.8 4.4 3.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 EME31570.1 - 0.053 13.4 1.0 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.23 EME31572.1 - 8.1e-89 297.8 0.0 1.3e-88 297.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.13 EME31572.1 - 1.9e-40 138.1 0.2 5e-40 136.7 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME31572.1 - 9.4e-35 119.3 0.0 2.6e-34 117.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EME31572.1 - 1.9e-28 98.9 0.0 5.9e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AMP-binding_C PF13193.1 EME31572.1 - 1.4e-15 58.0 0.0 5.3e-15 56.1 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CO_dh PF02552.11 EME31572.1 - 0.0071 15.9 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GH3 PF03321.8 EME31572.1 - 0.0091 14.5 0.1 0.04 12.4 0.1 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Myb_DNA-binding PF00249.26 EME31573.1 - 2.5e-11 43.4 0.0 6.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME31573.1 - 1.9e-06 27.8 0.5 1.9e-06 27.8 0.4 2.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Cob_adeno_trans PF01923.13 EME31575.1 - 4.4e-47 159.8 0.0 6.9e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase TraS PF10624.4 EME31576.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF1076 PF06416.7 EME31576.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) RRM_6 PF14259.1 EME31577.1 - 5.8e-07 29.3 0.0 3.4e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME31577.1 - 4.4e-06 26.2 0.0 0.00093 18.7 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31577.1 - 0.0015 18.3 0.0 0.024 14.4 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_98C PF08307.6 EME31577.1 - 0.0091 15.2 0.5 0.012 14.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain Lycopene_cycl PF05834.7 EME31578.1 - 1.6e-96 323.5 0.0 1.9e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME31578.1 - 1.1e-09 37.7 0.0 0.00017 20.5 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME31578.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31578.1 - 1.9e-05 23.8 0.0 0.00038 19.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EME31578.1 - 4e-05 23.4 0.0 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME31578.1 - 0.00026 21.1 0.0 0.00092 19.3 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME31578.1 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME31578.1 - 0.00055 18.5 0.0 0.0034 15.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 EME31578.1 - 0.00055 18.6 0.0 0.0066 15.1 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EME31578.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EME31578.1 - 0.0029 16.5 0.0 0.059 12.2 0.0 2.3 1 1 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EME31578.1 - 0.0037 16.2 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME31578.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EME31578.1 - 0.019 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YokU PF14122.1 EME31578.1 - 0.028 14.1 0.1 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 YokU-like protein TrkA_N PF02254.13 EME31578.1 - 0.039 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain bZIP_2 PF07716.10 EME31579.1 - 9.5e-06 25.3 18.3 0.00014 21.5 12.7 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EME31579.1 - 2.3e-05 24.2 16.9 2.3e-05 24.2 11.7 2.1 2 1 0 2 2 1 1 bZIP transcription factor Cauli_AT PF03233.8 EME31579.1 - 7.9e-05 22.4 1.4 9.3e-05 22.1 1.0 1.1 1 0 0 1 1 1 1 Aphid transmission protein bZIP_Maf PF03131.12 EME31579.1 - 0.00024 21.3 8.8 0.00046 20.4 6.1 1.5 1 1 0 1 1 1 1 bZIP Maf transcription factor BicD PF09730.4 EME31579.1 - 0.0048 15.3 6.7 0.0048 15.3 4.6 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF342 PF03961.8 EME31579.1 - 0.0096 14.3 3.3 0.01 14.3 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) APG17 PF04108.7 EME31579.1 - 0.024 13.4 2.9 0.027 13.2 2.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 APG6 PF04111.7 EME31579.1 - 0.063 12.3 3.3 0.07 12.1 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IFP_35_N PF07334.8 EME31579.1 - 0.071 13.0 4.6 2.7 8.0 1.2 2.5 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus COG2 PF06148.6 EME31579.1 - 0.086 12.7 3.9 0.11 12.3 2.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Kinesin-relat_1 PF12711.2 EME31579.1 - 0.087 13.2 9.2 0.12 12.8 5.9 1.5 1 1 1 2 2 2 0 Kinesin motor PRP3 PF08572.5 EME31579.1 - 0.092 12.1 3.6 0.11 11.8 2.5 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Adeno_PIX PF03955.9 EME31579.1 - 0.093 13.2 0.5 0.11 13.0 0.4 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) GAS PF13851.1 EME31579.1 - 0.11 11.6 11.3 0.18 10.9 7.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EME31579.1 - 0.13 11.8 9.6 0.15 11.6 6.7 1.1 1 0 0 1 1 1 0 IncA protein Fzo_mitofusin PF04799.8 EME31579.1 - 0.25 10.7 4.0 0.32 10.3 2.2 1.5 1 1 1 2 2 2 0 fzo-like conserved region GrpE PF01025.14 EME31579.1 - 0.29 10.6 3.1 0.36 10.3 2.1 1.2 1 0 0 1 1 1 0 GrpE Tnp_P_element PF12017.3 EME31579.1 - 0.38 9.9 2.4 0.38 9.9 0.9 1.5 1 1 1 2 2 2 0 Transposase protein Herpes_BLRF2 PF05812.7 EME31579.1 - 1.3 8.8 12.6 3 7.6 0.1 3.0 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 EME31579.1 - 1.7 8.9 7.2 4.7 7.5 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mto2_bdg PF12808.2 EME31579.1 - 1.8 8.7 11.2 1.6 8.9 5.8 2.3 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 EME31579.1 - 2.6 7.6 7.5 4.4 6.8 4.1 2.2 1 1 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 EME31579.1 - 7.1 7.0 14.0 15 5.9 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Orthoreo_P10 PF07204.6 EME31580.1 - 0.19 11.5 8.3 0.17 11.6 4.6 1.8 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3753 PF12575.3 EME31580.1 - 3 7.6 6.2 0.52 10.1 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) HAP2-GCS1 PF10699.4 EME31581.1 - 2.2e-19 69.1 2.2 8e-19 67.3 0.2 2.6 2 0 0 2 2 2 1 Male gamete fusion factor DUF1034 PF06280.7 EME31581.1 - 0.018 15.4 0.9 4.4 7.7 0.1 2.6 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) UPF1_Zn_bind PF09416.5 EME31584.1 - 4.7e-67 224.3 3.5 7.4e-66 220.4 0.5 3.0 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EME31584.1 - 5e-59 199.0 0.0 1.2e-58 197.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME31584.1 - 5e-56 189.9 2.8 7.7e-56 189.2 1.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME31584.1 - 2.3e-15 56.0 0.2 1.2e-14 53.8 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EME31584.1 - 4e-14 52.6 0.0 6e-13 48.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EME31584.1 - 4.6e-06 26.5 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EME31584.1 - 4.7e-05 23.0 0.2 0.1 12.1 0.0 3.4 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EME31584.1 - 0.00016 21.0 0.2 0.008 15.5 0.3 2.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EME31584.1 - 0.0017 17.3 2.5 0.003 16.5 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EME31584.1 - 0.0027 17.7 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME31584.1 - 0.0044 17.1 0.3 0.03 14.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EME31584.1 - 0.017 14.5 0.1 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EME31584.1 - 0.02 14.1 0.0 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EME31584.1 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SpoIIE PF07228.7 EME31585.1 - 4.7e-11 42.7 0.1 6.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EME31585.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EME31585.1 - 2.8e-05 23.6 0.1 0.031 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C CAF1A PF12253.3 EME31586.1 - 2.5e-16 59.5 2.0 2.5e-16 59.5 1.4 3.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A PI3_PI4_kinase PF00454.22 EME31587.1 - 1.2e-41 142.7 0.0 3.8e-41 141.0 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EME31587.1 - 1.2e-08 34.1 0.0 2.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 FATC domain S6PP PF05116.8 EME31588.1 - 3.7e-07 29.7 0.2 0.0002 20.7 0.1 2.9 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EME31588.1 - 7.1e-06 25.7 0.1 0.0023 17.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ku PF02735.11 EME31589.1 - 5.6e-27 94.4 0.0 8.9e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EME31589.1 - 2.2e-15 56.6 1.9 3.4e-15 55.9 0.1 2.2 3 0 0 3 3 3 1 Ku C terminal domain like Ku_N PF03731.10 EME31589.1 - 2.9e-05 23.6 0.0 9.8e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EME31589.1 - 0.0057 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Phage_HK97_TLTM PF06120.6 EME31589.1 - 0.12 11.7 0.2 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Ku PF02735.11 EME31590.1 - 5.3e-27 94.5 0.0 9.8e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EME31590.1 - 1.5e-15 57.1 0.2 1.5e-15 57.1 0.1 2.2 3 0 0 3 3 3 1 Ku C terminal domain like Ku_N PF03731.10 EME31590.1 - 3.2e-05 23.4 0.0 0.00011 21.7 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EME31590.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Phage_HK97_TLTM PF06120.6 EME31590.1 - 0.062 12.6 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Tail length tape measure protein tRNA-synt_1e PF01406.14 EME31591.1 - 5.7e-109 363.8 0.3 7.3e-109 363.5 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EME31591.1 - 1.2e-11 43.9 0.3 2.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EME31591.1 - 7.1e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.17 EME31591.1 - 0.0043 15.1 0.0 0.0079 14.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EME31591.1 - 0.041 12.5 0.0 0.35 9.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) IF-2B PF01008.12 EME31592.1 - 1.4e-48 165.3 0.0 1.9e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Acyl-CoA_dh_1 PF00441.19 EME31592.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain IFT57 PF10498.4 EME31592.1 - 0.035 12.8 0.4 0.052 12.2 0.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2378 PF09536.5 EME31592.1 - 0.065 12.7 0.1 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2378) Hep_59 PF07052.6 EME31592.1 - 0.095 13.0 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 polyprenyl_synt PF00348.12 EME31593.1 - 1.5e-73 246.8 0.0 2e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase XPC-binding PF09280.6 EME31594.1 - 4.2e-21 74.1 10.1 8.6e-21 73.1 7.0 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EME31594.1 - 4.3e-16 58.2 3.6 2e-12 46.5 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EME31594.1 - 5.6e-16 57.6 0.2 5.1e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EME31594.1 - 0.00024 20.7 0.7 0.00073 19.1 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF3306 PF11748.3 EME31594.1 - 0.0016 19.1 2.8 0.0053 17.3 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) Rad60-SLD_2 PF13881.1 EME31594.1 - 0.01 15.7 0.7 0.024 14.5 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME31594.1 - 0.012 15.7 0.7 0.03 14.4 0.5 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EME31594.1 - 0.061 13.2 0.0 17 5.3 0.0 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3173 PF11372.3 EME31594.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) DUF2259 PF10016.4 EME31596.1 - 0.0061 16.3 2.3 0.0061 16.3 1.6 1.6 2 0 0 2 2 2 1 Predicted secreted protein (DUF2259) DUF2149 PF09919.4 EME31596.1 - 2.4 8.3 5.7 0.27 11.3 0.4 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) Reo_sigmaC PF04582.7 EME31596.1 - 3.3 6.7 9.6 2.4 7.2 2.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein LSM PF01423.17 EME31597.1 - 4.3e-18 64.6 0.5 5.4e-18 64.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain Ank_2 PF12796.2 EME31598.1 - 1.4e-15 57.3 0.3 6.6e-11 42.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME31598.1 - 1.5e-12 46.6 0.3 9.7e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EME31598.1 - 1.6e-11 44.0 0.1 1.9e-06 27.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME31598.1 - 1.1e-10 40.6 0.2 6.8e-06 25.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EME31598.1 - 3.1e-09 37.0 0.2 0.00022 21.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) LIM PF00412.17 EME31599.1 - 9.4e-09 35.2 12.5 2.2e-08 34.0 8.7 1.7 1 0 0 1 1 1 1 LIM domain BOP1NT PF08145.7 EME31599.1 - 0.01 15.6 8.5 0.014 15.1 5.9 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain ABC2_membrane_3 PF12698.2 EME31600.1 - 3e-23 82.4 29.4 4.3e-23 81.8 20.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 EME31600.1 - 8.8e-23 81.1 0.0 2.3e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME31600.1 - 1.9e-10 41.2 0.2 5.9e-07 29.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EME31600.1 - 0.0085 15.6 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME31600.1 - 0.0087 16.4 0.1 0.0087 16.4 0.1 2.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EME31600.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EME31600.1 - 0.089 12.3 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EME31600.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EME31600.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 EME31600.1 - 0.29 9.9 18.6 4.2 6.1 11.1 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.20 EME31601.1 - 9.4e-59 198.6 0.0 1.2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31601.1 - 4.4e-26 91.4 0.0 5.6e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31601.1 - 6.5e-07 28.5 0.0 7.2e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME31601.1 - 0.0006 19.6 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME31601.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EME31601.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0016 PF01169.14 EME31602.1 - 9.4e-40 134.6 19.7 3.3e-20 71.9 5.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EME31602.1 - 2.9e-05 23.6 7.2 6.6e-05 22.4 5.0 1.5 1 1 0 1 1 1 1 Integral membrane protein TerC family YqhR PF11085.3 EME31602.1 - 0.035 13.6 1.1 0.064 12.7 0.8 1.5 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF3995 PF13160.1 EME31602.1 - 0.087 12.8 4.9 2.5 8.1 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF3961 PF13106.1 EME31602.1 - 0.4 10.2 3.6 8.4 6.0 0.8 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Herpes_US9 PF06072.6 EME31602.1 - 1.9 8.4 4.6 0.8 9.5 0.5 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Fig1 PF12351.3 EME31602.1 - 5.1 6.9 9.5 1.6 8.5 1.5 2.4 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Methyltransf_PK PF05891.7 EME31603.1 - 3.1e-72 242.4 0.0 4.1e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EME31603.1 - 9.6e-10 39.0 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME31603.1 - 4.2e-08 33.4 0.6 3.6e-07 30.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31603.1 - 4.8e-08 33.3 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME31603.1 - 4.7e-07 29.3 0.0 8.9e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME31603.1 - 1.6e-05 25.2 0.0 4.3e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31603.1 - 1.7e-05 24.5 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EME31603.1 - 6.7e-05 22.1 0.0 0.00017 20.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EME31603.1 - 0.00012 21.6 0.1 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME31603.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EME31603.1 - 0.051 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3944 PF13099.1 EME31603.1 - 1.3 8.5 4.1 0.52 9.8 0.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) Pterin_4a PF01329.14 EME31604.1 - 9.1e-23 79.8 0.1 1.1e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Ribosomal_L4 PF00573.17 EME31606.1 - 3.6e-47 160.2 0.4 5.5e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EME31606.1 - 3.1e-23 81.4 6.5 3.1e-23 81.4 4.5 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain ECH PF00378.15 EME31607.1 - 1.2e-59 201.4 0.1 1.4e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SDH_sah PF01972.11 EME31607.1 - 0.01 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase ECH_C PF13766.1 EME31607.1 - 0.098 12.8 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Prp19 PF08606.6 EME31608.1 - 2.9e-29 100.5 1.9 3.6e-29 100.2 0.7 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EME31608.1 - 6.4e-20 70.2 3.6 2.3e-06 27.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat zf-Nse PF11789.3 EME31608.1 - 3.4e-07 29.6 0.0 1e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nbas_N PF15492.1 EME31608.1 - 0.003 16.6 0.0 0.011 14.8 0.0 2.0 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal DivIC PF04977.10 EME31608.1 - 0.21 11.0 8.2 0.024 14.1 2.3 1.9 2 0 0 2 2 2 0 Septum formation initiator Cpn60_TCP1 PF00118.19 EME31609.1 - 5.8e-116 387.9 2.8 6.8e-116 387.7 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glycos_transf_1 PF00534.15 EME31610.1 - 8.1e-15 54.6 0.1 8.1e-14 51.4 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME31610.1 - 7.1e-10 39.1 0.0 1.9e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME31610.1 - 3.8e-09 36.6 0.0 2e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF758 PF05527.6 EME31610.1 - 0.061 12.9 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Glyco_transf_4 PF13439.1 EME31610.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Adap_comp_sub PF00928.16 EME31611.1 - 2.3e-20 72.8 0.2 3.4e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME31611.1 - 1.5e-07 31.2 0.7 2.2e-07 30.6 0.1 1.5 2 0 0 2 2 2 1 Clathrin adaptor complex small chain LRR_6 PF13516.1 EME31612.1 - 2.1e-25 85.8 60.8 0.037 14.1 0.1 18.8 18 1 1 19 19 19 11 Leucine Rich repeat LRR_4 PF12799.2 EME31612.1 - 1.8e-23 81.7 50.6 0.00088 18.8 1.0 11.1 3 2 6 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME31612.1 - 1.3e-13 50.4 60.9 0.00066 19.3 1.2 9.7 3 2 9 12 12 12 10 Leucine rich repeat LRR_1 PF00560.28 EME31612.1 - 1.2e-11 42.9 66.1 1.1 9.5 0.5 17.0 14 3 2 16 16 16 6 Leucine Rich Repeat LRR_7 PF13504.1 EME31612.1 - 6.6e-05 22.4 59.9 3.3 8.3 0.1 16.1 15 1 1 16 16 16 2 Leucine rich repeat tRNA_U5-meth_tr PF05958.6 EME31613.1 - 5.9e-19 67.9 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EME31613.1 - 7.9e-11 41.7 0.1 2.2e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME31613.1 - 8.7e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EME31613.1 - 3.8e-06 26.5 0.0 8.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EME31613.1 - 4.3e-06 26.1 0.1 9.2e-06 25.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EME31613.1 - 2e-05 25.1 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME31613.1 - 5.5e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein TRAM PF01938.15 EME31613.1 - 9.7e-05 22.0 0.1 0.0002 21.1 0.1 1.6 1 0 0 1 1 1 1 TRAM domain DOT1 PF08123.8 EME31613.1 - 0.00054 19.3 0.1 0.0018 17.6 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 PrmA PF06325.8 EME31613.1 - 0.00088 18.4 0.1 0.0029 16.7 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EME31613.1 - 0.00095 19.4 0.4 0.005 17.1 0.0 2.4 4 0 0 4 4 2 1 Methyltransferase domain UPF0020 PF01170.13 EME31613.1 - 0.00097 18.7 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EME31613.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EME31613.1 - 0.0051 17.2 0.0 0.016 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EME31613.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 DNA methylase NodS PF05401.6 EME31613.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DAO PF01266.19 EME31614.1 - 4e-15 55.5 0.5 2.5e-14 52.9 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME31614.1 - 7.6e-13 48.2 0.3 1.9e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME31614.1 - 3.8e-07 29.4 0.1 8.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EME31614.1 - 7.1e-07 28.6 0.0 1.7e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EME31614.1 - 3.9e-06 26.1 1.1 2.2e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EME31614.1 - 3e-05 23.0 0.5 5.5e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME31614.1 - 7.5e-05 22.6 0.1 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME31614.1 - 0.00095 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME31614.1 - 0.0024 16.4 0.3 0.0045 15.4 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EME31614.1 - 0.018 13.8 0.1 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EME31614.1 - 0.038 14.4 0.6 0.12 12.7 0.3 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME31614.1 - 0.04 13.6 0.1 0.077 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EME31614.1 - 0.12 11.7 0.3 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Strep_67kDa_ant PF06100.6 EME31614.1 - 0.12 10.6 0.4 0.45 8.7 0.1 1.9 3 0 0 3 3 3 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Hep_59 PF07052.6 EME31615.1 - 0.0001 22.6 0.7 0.0001 22.6 0.5 2.4 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 RP-C_C PF11800.3 EME31615.1 - 0.88 9.2 6.0 1.2 8.8 4.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Nitr_red_assoc PF09655.5 EME31615.1 - 0.88 9.8 5.3 2.5 8.4 0.6 2.1 1 1 1 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) NDUFA12 PF05071.11 EME31615.1 - 1.2 9.6 7.2 0.91 10.0 3.7 1.9 1 1 1 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Fib_alpha PF08702.5 EME31615.1 - 3.2 7.8 8.5 1.9 8.5 4.3 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_M41 PF01434.13 EME31616.1 - 7e-74 247.8 0.0 1.1e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME31616.1 - 1.6e-44 151.2 0.0 3.7e-44 150.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME31616.1 - 2.3e-06 27.3 1.4 0.00013 21.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME31616.1 - 0.00012 22.2 0.8 0.012 15.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EME31616.1 - 0.0003 21.5 0.1 0.0015 19.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME31616.1 - 0.00037 20.1 0.3 0.0011 18.6 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EME31616.1 - 0.00039 19.5 0.0 0.0024 16.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EME31616.1 - 0.00087 19.3 2.8 0.016 15.2 0.1 3.5 3 1 0 3 3 2 1 AAA ATPase domain TIP49 PF06068.8 EME31616.1 - 0.0019 17.0 0.2 0.0035 16.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EME31616.1 - 0.0021 17.9 0.0 0.0069 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME31616.1 - 0.0023 17.3 0.1 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EME31616.1 - 0.0055 16.5 0.3 0.027 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME31616.1 - 0.006 16.5 0.5 0.055 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME31616.1 - 0.0071 15.7 3.3 4.8 6.5 0.1 4.0 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.1 EME31616.1 - 0.0079 15.7 0.4 1.6 8.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EME31616.1 - 0.016 15.0 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EME31616.1 - 0.018 14.1 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EME31616.1 - 0.03 14.6 0.3 0.095 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME31616.1 - 0.047 13.3 0.2 0.41 10.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EME31616.1 - 0.053 12.6 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.19 EME31617.1 - 2.3e-126 422.2 12.2 2.7e-126 422.0 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TAXi_C PF14541.1 EME31617.1 - 0.025 14.1 0.2 0.066 12.7 0.1 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal dCMP_cyt_deam_1 PF00383.17 EME31618.1 - 1e-26 92.5 1.6 1.8e-26 91.7 1.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME31618.1 - 0.00092 18.8 0.7 0.0019 17.8 0.5 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain AAA_17 PF13207.1 EME31618.1 - 0.0021 18.8 0.9 0.0072 17.1 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME31618.1 - 0.0044 17.3 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Neocarzinostat PF00960.13 EME31618.1 - 0.19 11.6 1.6 1.3 8.9 0.3 2.3 1 1 1 2 2 2 0 Neocarzinostatin family Noc2 PF03715.8 EME31619.1 - 5.2e-71 238.9 1.5 9.2e-71 238.1 1.1 1.3 1 0 0 1 1 1 1 Noc2p family CobN-Mg_chel PF02514.11 EME31620.1 - 0 1093.7 0.0 0 1093.5 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.3 EME31620.1 - 8.4e-52 175.2 0.4 1.5e-51 174.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Methyltransf_31 PF13847.1 EME31621.1 - 2.9e-10 39.9 0.0 4.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31621.1 - 3.2e-10 40.3 0.0 6.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME31621.1 - 6.5e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME31621.1 - 7.7e-09 35.8 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME31621.1 - 1.6e-06 28.4 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME31621.1 - 0.00011 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31621.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EME31621.1 - 0.0056 16.1 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 EME31621.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) ThiF PF00899.16 EME31621.1 - 0.0082 15.9 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 ThiF family DUF3082 PF11282.3 EME31622.1 - 2.5e-09 37.0 5.3 4.1e-09 36.3 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) 5TM-5TMR_LYT PF07694.7 EME31622.1 - 0.048 12.9 2.7 0.14 11.5 0.8 2.0 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Ribosomal_S8e PF01201.17 EME31623.1 - 2e-42 144.4 0.7 2e-42 144.4 0.5 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e bZIP_2 PF07716.10 EME31624.1 - 0.0063 16.3 16.3 0.0063 16.3 11.3 2.9 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME31624.1 - 0.0079 16.4 13.3 0.0079 16.4 9.2 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EME31624.1 - 0.012 15.5 14.2 0.012 15.5 9.8 2.2 2 1 1 3 3 2 0 bZIP transcription factor Phage_GP20 PF06810.6 EME31624.1 - 0.13 11.7 5.3 0.4 10.1 3.7 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_23 PF13476.1 EME31624.1 - 0.28 11.4 6.7 0.33 11.2 4.6 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_N PF10481.4 EME31624.1 - 0.31 10.3 13.4 0.017 14.5 4.5 1.9 1 1 1 2 2 2 0 Cenp-F N-terminal domain Jnk-SapK_ap_N PF09744.4 EME31624.1 - 0.41 10.6 10.1 0.75 9.7 7.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DivIVA PF05103.8 EME31624.1 - 0.41 10.6 11.1 0.27 11.2 1.5 2.9 2 1 1 3 3 3 0 DivIVA protein Seryl_tRNA_N PF02403.17 EME31624.1 - 0.98 9.4 10.6 2.7 8.0 7.3 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF658 PF04936.7 EME31624.1 - 1 9.2 5.9 0.41 10.4 2.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF658) H-kinase_dim PF02895.9 EME31624.1 - 1.3 9.4 6.4 8.3 6.8 4.4 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Ead_Ea22 PF13935.1 EME31624.1 - 5.6 7.2 9.1 0.45 10.8 1.9 2.3 2 2 1 3 3 3 0 Ead/Ea22-like protein APG6 PF04111.7 EME31624.1 - 7.5 5.5 17.2 0.11 11.5 7.0 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_3 PF00202.16 EME31625.1 - 3.3e-105 351.6 0.0 4.1e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III SPOUT_MTase PF02590.12 EME31626.1 - 1.7e-20 73.2 0.1 4.1e-20 72.0 0.1 1.6 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase DUF791 PF05631.9 EME31627.1 - 7.8e-107 357.0 17.5 1e-106 356.6 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EME31627.1 - 2.4e-18 65.9 38.0 2.1e-14 53.0 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CLASP_N PF12348.3 EME31628.1 - 7.2e-17 61.5 17.0 9.1e-08 31.7 2.0 6.2 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.17 EME31628.1 - 1.4e-10 40.2 9.4 0.0013 18.6 0.1 8.8 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.1 EME31628.1 - 9e-08 32.2 13.7 0.026 14.8 0.2 8.5 6 3 2 8 8 8 2 HEAT repeats DUF1477 PF07346.6 EME31628.1 - 0.00044 20.2 2.1 0.0046 16.9 0.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1477) HEAT_EZ PF13513.1 EME31628.1 - 0.0016 18.8 8.4 2.6 8.6 0.1 6.2 8 0 0 8 8 8 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EME31628.1 - 0.0055 16.6 0.8 0.55 10.2 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF3368 PF11848.3 EME31628.1 - 0.084 12.4 0.0 0.41 10.2 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) FAD-SLDH PF12318.3 EME31628.1 - 0.16 11.6 0.7 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase UreE_C PF05194.7 EME31629.1 - 6.4e-09 35.7 0.0 9.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.10 EME31629.1 - 0.0094 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.7 EME31630.1 - 6.4e-09 35.7 0.0 9.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.10 EME31630.1 - 0.0094 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain DHO_dh PF01180.16 EME31633.1 - 1.9e-97 325.8 0.0 2.2e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EME31633.1 - 0.018 14.2 1.8 0.081 12.1 0.1 2.1 1 1 1 2 2 2 0 PcrB family Phage_rep_O PF04492.8 EME31634.1 - 3.3 7.9 8.0 0.33 11.1 0.5 2.3 2 0 0 2 2 2 0 Bacteriophage replication protein O Pkinase PF00069.20 EME31636.1 - 2.9e-54 183.9 0.0 4.4e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31636.1 - 1e-33 116.4 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31636.1 - 8e-09 34.8 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME31636.1 - 0.14 11.8 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EME31637.1 - 2.9e-54 183.9 0.0 4.4e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31637.1 - 1e-33 116.4 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31637.1 - 8e-09 34.8 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME31637.1 - 0.14 11.8 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CUE PF02845.11 EME31638.1 - 9.4e-07 28.2 0.1 2.9e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 CUE domain HBS1_N PF08938.5 EME31638.1 - 0.033 14.3 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 HBS1 N-terminus DUF2630 PF10944.3 EME31638.1 - 0.12 12.4 0.9 0.59 10.2 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) Clathrin PF00637.15 EME31639.1 - 7.5e-150 492.4 1.6 3.2e-29 101.3 0.0 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EME31639.1 - 6.6e-30 102.8 0.2 3.1e-29 100.6 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EME31639.1 - 3.4e-23 80.2 0.2 6.4e-05 22.9 0.0 6.6 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_7 PF13176.1 EME31639.1 - 6.7e-07 28.6 5.4 0.87 9.5 0.0 6.4 5 1 0 5 5 5 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EME31639.1 - 0.0014 17.5 4.0 0.47 9.1 0.0 4.4 3 1 0 4 4 4 1 Coatomer WD associated region PPR PF01535.15 EME31639.1 - 0.0057 16.5 5.1 0.75 9.9 0.0 5.7 6 1 1 7 7 6 1 PPR repeat Clathrin-link PF09268.5 EME31639.1 - 0.0064 15.4 0.0 0.019 14.0 0.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 EME31639.1 - 0.015 15.2 12.2 0.5 10.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME31639.1 - 0.019 14.8 11.5 82 3.5 0.0 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME31639.1 - 0.019 15.5 23.0 9.4 7.1 0.0 10.9 13 1 0 13 13 11 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME31639.1 - 0.098 13.0 9.3 6.2 7.2 0.0 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat Vps39_1 PF10366.4 EME31639.1 - 0.3 11.1 9.1 9.1 6.3 0.1 6.1 7 0 0 7 7 7 0 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.1 EME31640.1 - 3.3e-20 72.2 9.6 0.00018 21.8 0.5 9.7 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EME31640.1 - 4e-19 68.0 27.8 0.00014 21.4 1.2 9.5 10 2 2 12 12 10 6 TPR repeat TPR_16 PF13432.1 EME31640.1 - 2.2e-17 63.2 25.8 0.00032 21.2 3.2 11.1 10 2 3 13 13 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME31640.1 - 6.1e-14 50.7 34.6 0.0078 16.0 0.1 13.1 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_1 PF00515.23 EME31640.1 - 9.2e-13 47.2 22.6 0.003 17.1 0.0 9.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME31640.1 - 5.5e-12 45.4 39.8 0.0021 17.9 2.0 10.2 8 4 3 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 EME31640.1 - 2.6e-11 43.0 26.6 3e-05 24.2 0.2 11.6 12 2 2 14 14 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME31640.1 - 4.3e-09 35.5 13.7 0.043 13.6 0.1 9.3 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME31640.1 - 5.7e-09 35.1 25.9 0.01 15.5 0.1 10.7 10 2 1 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME31640.1 - 3.5e-07 30.2 31.3 0.43 11.1 0.1 11.9 15 0 0 15 15 13 3 Tetratricopeptide repeat Apc3 PF12895.2 EME31640.1 - 3.1e-06 27.2 29.4 0.38 10.9 0.1 8.2 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EME31640.1 - 0.0003 20.7 16.6 3.5 8.0 0.0 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Xpo1 PF08389.7 EME31640.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.3 1 0 0 1 1 1 0 Exportin 1-like protein TPR_4 PF07721.9 EME31640.1 - 0.04 14.3 8.9 3.3 8.3 0.1 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME31640.1 - 0.086 12.8 0.0 0.086 12.8 0.0 9.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME31640.1 - 0.45 10.4 8.1 0.073 12.9 0.2 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat PRKCSH PF07915.8 EME31641.1 - 4.8e-11 43.3 0.8 4.8e-11 43.3 0.5 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EME31641.1 - 0.00016 21.1 0.0 0.00045 19.7 0.0 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Mito_carr PF00153.22 EME31642.1 - 2e-64 213.3 0.5 2.9e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Toxin_21 PF08091.6 EME31642.1 - 2 8.2 7.9 3.4 7.4 1.5 2.6 2 0 0 2 2 2 0 Spider insecticidal peptide UCH PF00443.24 EME31643.1 - 2.1e-50 171.3 0.1 3.4e-50 170.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME31643.1 - 1.1e-22 80.9 0.0 1.9e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EME31643.1 - 0.0073 15.6 6.1 0.032 13.5 1.5 3.3 3 1 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cyclin_N PF00134.18 EME31644.1 - 2.1e-16 59.6 1.0 2.1e-16 59.6 0.7 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EME31644.1 - 5.7e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat DUF399 PF04187.8 EME31645.1 - 9.5e-42 142.8 0.0 1.3e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF399 DUF4219 PF13961.1 EME31645.1 - 1.7 8.1 4.9 2 7.9 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) KAR9 PF08580.5 EME31646.1 - 0.13 10.5 8.6 0.15 10.3 6.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF572 PF04502.8 EME31646.1 - 0.99 8.5 12.3 1.1 8.4 8.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glycoprotein_G PF00802.14 EME31646.1 - 1.8 7.6 14.7 2.1 7.3 10.2 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Pol_alpha_B_N PF08418.5 EME31646.1 - 2 7.9 9.4 2.3 7.6 6.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2413 PF10310.4 EME31646.1 - 4.9 5.8 9.7 5.2 5.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RED_N PF07808.8 EME31647.1 - 2e-06 27.1 0.2 4.3e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 RED-like protein N-terminal region Pkinase PF00069.20 EME31648.1 - 2.1e-37 128.6 0.0 2.7e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31648.1 - 5.8e-14 51.7 0.0 7.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31648.1 - 0.0025 17.5 0.0 0.0071 16.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EME31648.1 - 0.053 12.2 0.1 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EME31649.1 - 1.3e-36 126.0 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31649.1 - 7.5e-13 48.1 0.0 2.1e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31649.1 - 0.0036 17.0 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EME31649.1 - 0.056 12.2 0.1 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Acetyltransf_1 PF00583.19 EME31650.1 - 2e-15 56.5 0.0 2.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME31650.1 - 1.7e-10 40.8 0.1 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME31650.1 - 2.9e-10 39.7 0.1 4.1e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EME31650.1 - 1.2e-07 31.8 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME31650.1 - 2.6e-07 30.8 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME31650.1 - 3.4e-07 30.2 0.0 4.9e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EME31650.1 - 0.0032 17.0 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME31650.1 - 0.0055 16.5 0.0 0.0072 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME31650.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3110 PF11360.3 EME31651.1 - 4.2e-23 80.9 0.0 6.4e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) ABC2_membrane PF01061.19 EME31652.1 - 7.5e-43 146.1 24.2 1.3e-42 145.3 16.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME31652.1 - 1.1e-27 96.9 0.1 1.8e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME31652.1 - 2.6e-10 40.7 1.7 5.6e-05 23.2 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EME31652.1 - 3e-06 26.7 0.1 0.0004 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME31652.1 - 6.9e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EME31652.1 - 8.7e-05 23.3 0.1 0.00024 21.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME31652.1 - 0.00015 20.9 0.2 0.00029 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EME31652.1 - 0.00055 18.9 0.0 0.00096 18.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EME31652.1 - 0.0012 18.3 0.0 0.0084 15.5 0.0 2.2 3 0 0 3 3 2 1 AAA-like domain SMC_N PF02463.14 EME31652.1 - 0.0015 17.8 0.1 0.0043 16.3 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME31652.1 - 0.0036 17.4 0.1 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME31652.1 - 0.0049 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME31652.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EME31652.1 - 0.0094 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EME31652.1 - 0.017 14.6 0.3 0.037 13.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EME31652.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EME31652.1 - 0.035 13.6 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME31652.1 - 0.037 13.9 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME31652.1 - 0.043 13.6 0.2 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME31652.1 - 0.043 13.4 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EME31652.1 - 0.046 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase SbcCD_C PF13558.1 EME31652.1 - 0.049 13.5 0.1 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PIF1 PF05970.9 EME31652.1 - 0.06 12.2 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_28 PF13521.1 EME31652.1 - 0.075 12.9 0.3 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME31652.1 - 0.088 12.5 0.1 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.1 EME31652.1 - 0.09 13.0 2.0 0.088 13.1 0.5 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EME31652.1 - 0.091 12.2 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 EME31652.1 - 0.092 11.9 0.1 0.25 10.5 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 EME31652.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EME31652.1 - 0.14 12.3 0.2 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.19 EME31653.1 - 8.7e-43 145.9 24.2 1.3e-42 145.3 16.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME31653.1 - 1.1e-27 96.9 0.1 1.8e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME31653.1 - 2.8e-10 40.6 1.7 6.2e-05 23.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EME31653.1 - 3.1e-06 26.7 0.1 0.00041 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME31653.1 - 7.1e-06 26.1 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EME31653.1 - 9e-05 23.2 0.1 0.00026 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME31653.1 - 0.00016 20.9 0.2 0.0003 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EME31653.1 - 0.00057 18.8 0.0 0.00098 18.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EME31653.1 - 0.0013 18.2 0.0 0.0086 15.5 0.0 2.2 3 0 0 3 3 2 1 AAA-like domain SMC_N PF02463.14 EME31653.1 - 0.0015 17.7 0.1 0.0044 16.2 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME31653.1 - 0.0037 17.4 0.1 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME31653.1 - 0.005 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME31653.1 - 0.0094 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EME31653.1 - 0.0095 15.6 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EME31653.1 - 0.018 14.5 0.3 0.038 13.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EME31653.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EME31653.1 - 0.036 13.6 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME31653.1 - 0.038 13.9 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME31653.1 - 0.044 13.4 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EME31653.1 - 0.045 13.6 0.2 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME31653.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase SbcCD_C PF13558.1 EME31653.1 - 0.049 13.5 0.1 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PIF1 PF05970.9 EME31653.1 - 0.062 12.2 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_23 PF13476.1 EME31653.1 - 0.07 13.4 1.6 0.092 13.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME31653.1 - 0.076 12.9 0.3 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME31653.1 - 0.091 12.4 0.1 0.57 9.8 0.0 2.1 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EME31653.1 - 0.092 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 EME31653.1 - 0.094 11.9 0.1 0.25 10.5 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 EME31653.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EME31653.1 - 0.14 12.3 0.2 0.32 11.1 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.22 EME31654.1 - 9.9e-16 57.5 0.0 2.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ham1p_like PF01725.11 EME31654.1 - 3.9e-07 29.6 0.0 1.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Ham1 family DUF2048 PF09752.4 EME31655.1 - 2.4e-71 240.4 0.0 3e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 EME31655.1 - 5.3e-11 42.8 0.2 7.2e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME31655.1 - 8.3e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME31655.1 - 0.0023 17.3 0.1 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EME31655.1 - 0.0066 16.0 0.2 0.028 13.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EME31655.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 EME31656.1 - 1.7e-55 188.3 0.0 2.1e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 EME31656.1 - 1.1e-05 25.2 0.1 2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME31656.1 - 0.00014 21.8 0.1 0.00017 21.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME31656.1 - 0.0018 17.7 0.1 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EME31656.1 - 0.019 14.4 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 EME31656.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal polyprenyl_synt PF00348.12 EME31657.1 - 1.5e-51 174.7 0.1 2.9e-51 173.8 0.1 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EME31657.1 - 0.01 15.3 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RICTOR_phospho PF14665.1 EME31658.1 - 0.064 13.3 1.4 0.092 12.8 1.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Sugar_tr PF00083.19 EME31659.1 - 1.1e-41 142.9 27.8 3e-40 138.1 19.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME31659.1 - 1.5e-21 76.5 31.7 1.9e-17 63.0 22.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME31659.1 - 3.5e-05 22.3 22.1 0.023 13.1 0.4 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein PSS PF03034.10 EME31660.1 - 2.1e-75 253.7 2.1 2.2e-75 253.6 0.7 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Gcd10p PF04189.8 EME31660.1 - 4.3e-39 134.4 0.0 7.7e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family IF3_N PF05198.11 EME31660.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain TPR_11 PF13414.1 EME31661.1 - 3.1e-24 84.4 4.1 2e-18 65.7 0.6 3.1 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EME31661.1 - 1.2e-18 65.8 6.0 1.5e-05 24.3 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME31661.1 - 1.4e-14 52.7 10.2 3e-05 23.5 0.1 4.8 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME31661.1 - 3.6e-09 36.4 0.6 0.0052 17.2 0.0 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME31661.1 - 4.5e-09 35.7 4.5 0.005 16.9 0.0 4.5 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME31661.1 - 9.4e-09 35.4 0.2 6.3e-05 23.2 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME31661.1 - 6.2e-07 29.9 0.1 0.017 15.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME31661.1 - 2e-06 27.5 0.6 0.0021 17.8 0.0 3.1 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EME31661.1 - 1.1e-05 24.8 0.9 0.025 14.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME31661.1 - 1.4e-05 24.9 3.0 0.0017 18.2 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME31661.1 - 3.7e-05 23.1 1.2 0.68 9.8 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat SGT1 PF07093.6 EME31661.1 - 9.6e-05 20.9 1.6 9.6e-05 20.9 1.1 2.2 1 1 1 2 2 2 1 SGT1 protein TPR_9 PF13371.1 EME31661.1 - 0.00055 19.7 0.1 0.18 11.6 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EME31661.1 - 0.0062 16.9 6.7 0.057 13.9 0.1 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EME31661.1 - 0.015 15.4 0.5 0.3 11.2 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EME31661.1 - 0.027 14.7 0.5 0.24 11.6 0.3 2.4 2 1 0 2 2 2 0 Bacterial transcriptional activator domain HEPN PF05168.9 EME31661.1 - 0.1 12.4 1.4 6 6.7 0.0 3.2 2 1 0 3 3 3 0 HEPN domain Not1 PF04054.10 EME31662.1 - 5.4e-128 427.0 1.1 5.4e-128 427.0 0.7 2.6 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EME31662.1 - 7.7e-44 148.9 1.2 7.7e-44 148.9 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Ribosomal_60s PF00428.14 EME31662.1 - 2.4 8.6 9.6 8.1 6.9 6.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_L7Ae PF01248.21 EME31663.1 - 5.2e-20 70.7 0.1 8.4e-20 70.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family BTB_2 PF02214.17 EME31664.1 - 3e-19 68.9 0.0 4.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain K-box PF01486.12 EME31664.1 - 0.015 15.0 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 K-box region Glypican PF01153.14 EME31664.1 - 0.018 13.7 0.0 0.022 13.3 0.0 1.0 1 0 0 1 1 1 0 Glypican BTB PF00651.26 EME31664.1 - 0.074 13.0 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF445 PF04286.7 EME31666.1 - 0.018 14.6 13.4 0.047 13.2 9.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) WD40 PF00400.27 EME31666.1 - 0.022 14.6 0.1 9.4 6.2 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Pox_A21 PF05323.7 EME31666.1 - 0.037 14.4 0.1 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Poxvirus A21 Protein YpjP PF14005.1 EME31666.1 - 0.19 11.4 1.7 5.7 6.7 0.1 3.4 2 1 1 3 3 3 0 YpjP-like protein SNF2_N PF00176.18 EME31667.1 - 7.3e-67 225.2 0.0 1.4e-66 224.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME31667.1 - 3.7e-12 45.9 0.0 1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.3 EME31667.1 - 7.2e-09 34.7 5.1 1.4e-05 23.8 0.2 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF3535) HEAT_2 PF13646.1 EME31667.1 - 2.4e-05 24.5 2.9 0.0098 16.1 0.0 5.0 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.17 EME31667.1 - 0.002 18.0 9.3 26 5.2 0.0 8.0 9 0 0 9 9 9 0 HEAT repeat Ipi1_N PF12333.3 EME31667.1 - 0.0099 15.8 0.0 0.25 11.3 0.0 3.4 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EME31667.1 - 0.021 15.2 2.8 1.2e+02 3.3 0.0 6.1 6 0 0 6 6 6 0 HEAT-like repeat DUF1546 PF07571.8 EME31667.1 - 0.12 12.5 0.7 12 6.1 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1546) zf-UBR PF02207.15 EME31668.1 - 2e-21 75.4 7.5 2e-21 75.4 5.2 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EME31668.1 - 0.0022 17.7 2.1 0.0022 17.7 1.5 5.2 5 1 1 6 6 6 1 Ring finger domain SR-25 PF10500.4 EME31668.1 - 0.06 12.8 12.5 0.12 11.7 8.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TBCA PF02970.11 EME31669.1 - 5.3e-10 39.2 9.5 5.3e-10 39.2 6.6 1.5 1 1 1 2 2 2 1 Tubulin binding cofactor A Vps51 PF08700.6 EME31669.1 - 0.0021 17.8 2.7 0.0057 16.4 1.9 1.9 1 1 0 1 1 1 1 Vps51/Vps67 Latarcin PF10279.4 EME31669.1 - 0.0091 16.1 2.7 0.011 15.8 1.8 1.2 1 0 0 1 1 1 1 Latarcin precursor IFT57 PF10498.4 EME31669.1 - 0.023 13.4 7.1 0.024 13.3 4.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MCP_N PF05581.7 EME31669.1 - 0.033 14.3 0.6 0.083 13.0 0.1 1.7 1 1 1 2 2 2 0 Vibrio chemotaxis protein N terminus DUF2937 PF11157.3 EME31669.1 - 0.066 12.5 5.7 0.082 12.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) V-SNARE_C PF12352.3 EME31669.1 - 0.099 12.7 1.7 0.22 11.6 0.6 2.2 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Fzo_mitofusin PF04799.8 EME31669.1 - 0.12 11.7 4.8 0.13 11.6 3.3 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF87 PF01935.12 EME31669.1 - 0.12 12.1 2.2 0.13 12.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF904 PF06005.7 EME31669.1 - 0.18 12.1 11.8 0.081 13.2 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Sec5 PF15469.1 EME31669.1 - 0.21 11.3 4.7 0.28 10.9 3.2 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 Ndc1_Nup PF09531.5 EME31669.1 - 0.22 9.8 1.6 0.22 9.8 1.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ResIII PF04851.10 EME31669.1 - 0.23 11.2 2.4 0.26 11.1 1.6 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TMPIT PF07851.8 EME31669.1 - 0.26 10.2 7.6 0.28 10.1 5.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Mt_ATP-synt_D PF05873.7 EME31669.1 - 0.31 10.6 4.1 0.35 10.4 2.9 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Aida_N PF08910.5 EME31669.1 - 0.41 10.8 6.6 0.081 13.1 1.2 1.9 1 1 1 2 2 2 0 Aida N-terminus DUF3829 PF12889.2 EME31669.1 - 0.55 9.3 8.0 0.62 9.1 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Rho_Binding PF08912.6 EME31669.1 - 0.58 10.4 9.4 0.3 11.4 0.9 2.2 1 1 1 2 2 2 0 Rho Binding Prefoldin PF02996.12 EME31669.1 - 0.79 9.3 7.1 0.61 9.7 1.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit Enkurin PF13864.1 EME31669.1 - 0.84 9.8 8.6 1.1 9.5 6.0 1.1 1 0 0 1 1 1 0 Calmodulin-binding FCH PF00611.18 EME31669.1 - 0.92 9.7 6.9 0.48 10.6 0.5 2.3 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.6 EME31669.1 - 0.93 9.3 4.0 2.2 8.1 2.7 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4298 PF14131.1 EME31669.1 - 1.1 9.2 7.1 5.2 7.0 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) PilO PF04350.8 EME31669.1 - 1.3 8.8 7.2 4.8 7.0 1.1 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO Peptidase_M29 PF02073.10 EME31669.1 - 1.4 7.6 5.9 1.5 7.5 4.1 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) DUF4407 PF14362.1 EME31669.1 - 1.5 7.7 6.2 1.7 7.5 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EME31669.1 - 1.6 8.3 11.0 2.1 7.8 7.6 1.2 1 0 0 1 1 1 0 IncA protein DASH_Dad3 PF08656.5 EME31669.1 - 1.6 8.4 6.0 0.27 10.9 1.5 1.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 Synaptobrevin PF00957.16 EME31669.1 - 1.7 8.2 4.6 1.2 8.8 1.4 2.0 1 1 1 2 2 2 0 Synaptobrevin Tho2 PF11262.3 EME31669.1 - 1.8 7.5 6.2 1.9 7.4 4.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UPF0449 PF15136.1 EME31669.1 - 2.1 8.5 6.8 12 6.2 4.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF342 PF03961.8 EME31669.1 - 2.8 6.2 5.9 2.9 6.1 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 EME31669.1 - 5.2 6.9 6.5 3.7 7.4 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Viral_P18 PF04521.8 EME31669.1 - 7 6.1 6.7 2.7 7.4 1.0 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TBCA PF02970.11 EME31670.1 - 7.1e-16 58.0 11.0 7.8e-16 57.9 7.0 1.5 1 1 1 2 2 2 1 Tubulin binding cofactor A Vps51 PF08700.6 EME31670.1 - 0.0022 17.7 4.5 0.022 14.5 3.1 2.1 1 1 0 1 1 1 1 Vps51/Vps67 MCP_N PF05581.7 EME31670.1 - 0.0067 16.5 1.9 0.14 12.3 0.1 2.1 1 1 1 2 2 2 1 Vibrio chemotaxis protein N terminus Poty_PP PF08440.5 EME31670.1 - 0.01 14.9 3.4 0.013 14.6 2.4 1.0 1 0 0 1 1 1 0 Potyviridae polyprotein Latarcin PF10279.4 EME31670.1 - 0.015 15.4 3.0 0.021 14.9 1.9 1.4 1 1 0 1 1 1 0 Latarcin precursor Serine_rich PF08824.5 EME31670.1 - 0.032 13.9 3.4 0.041 13.5 2.3 1.2 1 1 0 1 1 1 0 Serine rich protein interaction domain ResIII PF04851.10 EME31670.1 - 0.034 13.9 4.2 0.042 13.6 2.9 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1268 PF06896.6 EME31670.1 - 0.045 14.0 1.7 0.053 13.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) DUF87 PF01935.12 EME31670.1 - 0.062 13.1 2.6 0.068 12.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF4509 PF14970.1 EME31670.1 - 0.075 12.6 2.6 0.075 12.6 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) DUF2937 PF11157.3 EME31670.1 - 0.09 12.1 6.8 0.29 10.4 4.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF904 PF06005.7 EME31670.1 - 0.098 12.9 14.2 0.13 12.6 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 EME31670.1 - 0.11 12.2 6.0 0.96 9.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 EME31670.1 - 0.16 11.3 4.9 0.2 11.0 3.4 1.3 1 1 0 1 1 1 0 fzo-like conserved region Mt_ATP-synt_D PF05873.7 EME31670.1 - 0.16 11.6 3.8 0.18 11.4 2.6 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Sec5 PF15469.1 EME31670.1 - 0.29 10.8 4.8 0.38 10.4 3.2 1.3 1 1 0 1 1 1 0 Exocyst complex component Sec5 TMPIT PF07851.8 EME31670.1 - 0.32 10.0 7.7 0.37 9.8 5.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Val_tRNA-synt_C PF10458.4 EME31670.1 - 0.42 10.7 3.9 16 5.6 0.1 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF342 PF03961.8 EME31670.1 - 0.44 8.8 6.1 0.5 8.7 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V-SNARE_C PF12352.3 EME31670.1 - 0.45 10.6 3.7 0.29 11.2 0.3 2.5 3 1 0 3 3 2 0 Snare region anchored in the vesicle membrane C-terminus Aida_N PF08910.5 EME31670.1 - 0.52 10.5 6.4 0.13 12.4 1.2 2.0 1 1 1 2 2 2 0 Aida N-terminus IncA PF04156.9 EME31670.1 - 0.56 9.7 10.7 0.71 9.4 7.4 1.2 1 0 0 1 1 1 0 IncA protein Rho_Binding PF08912.6 EME31670.1 - 0.79 10.0 9.0 0.46 10.8 0.9 2.2 1 1 1 2 2 2 0 Rho Binding SlyX PF04102.7 EME31670.1 - 0.9 9.9 9.1 3.6 8.0 0.9 2.4 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.1 EME31670.1 - 1 8.2 6.2 1.1 8.1 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dad3 PF08656.5 EME31670.1 - 1.1 9.0 5.8 0.4 10.4 1.4 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 COG2 PF06148.6 EME31670.1 - 1.1 9.1 6.2 5.9 6.7 2.6 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PilO PF04350.8 EME31670.1 - 1.1 9.1 8.7 5.2 6.9 1.0 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO DnaI_N PF07319.6 EME31670.1 - 1.1 9.5 5.1 1.4 9.2 3.2 1.5 1 1 0 1 1 1 0 Primosomal protein DnaI N-terminus DUF4298 PF14131.1 EME31670.1 - 1.5 8.7 6.7 6.3 6.7 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Syntaxin PF00804.20 EME31670.1 - 1.5 8.9 6.3 4.9 7.3 0.6 2.0 1 1 1 2 2 2 0 Syntaxin Enkurin PF13864.1 EME31670.1 - 2.3 8.4 9.5 3.1 8.0 6.6 1.2 1 0 0 1 1 1 0 Calmodulin-binding Adeno_PIX PF03955.9 EME31670.1 - 2.6 8.6 6.3 11 6.5 1.0 2.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Tho2 PF11262.3 EME31670.1 - 3.1 6.7 6.7 3.5 6.5 4.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 APG6 PF04111.7 EME31670.1 - 3.7 6.5 10.6 4.2 6.3 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0449 PF15136.1 EME31670.1 - 3.7 7.8 7.5 17 5.6 3.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Atg14 PF10186.4 EME31670.1 - 4.3 6.2 8.9 5 5.9 6.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Viral_P18 PF04521.8 EME31670.1 - 9.1 5.7 7.5 3.8 6.9 1.0 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein WD40 PF00400.27 EME31671.1 - 8.4e-18 63.5 0.2 2e-07 30.6 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Kelch_1 PF01344.20 EME31671.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 Kelch motif PQQ_3 PF13570.1 EME31671.1 - 0.62 10.4 5.9 28 5.1 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Aminotran_1_2 PF00155.16 EME31672.1 - 1.2e-49 169.2 0.0 1.5e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME31672.1 - 0.0019 17.0 0.0 0.033 12.9 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME31672.1 - 0.0041 15.4 0.0 0.0063 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME31672.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_85 PF03644.8 EME31673.1 - 2e-75 253.8 1.1 3e-75 253.2 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 WD40 PF00400.27 EME31674.1 - 5.8e-40 133.7 16.3 6e-11 41.7 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 EME31674.1 - 2.4e-06 27.3 0.4 7.8e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Apc4_WD40 PF12894.2 EME31674.1 - 0.043 13.3 1.0 0.38 10.2 0.0 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_topoisoIV PF00521.15 EME31675.1 - 3.7e-143 477.4 0.0 7.8e-143 476.3 0.0 1.5 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 EME31675.1 - 1.5e-38 129.8 0.1 1.1e-07 30.9 0.0 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller DUF3508 PF12018.3 EME31675.1 - 0.0082 15.1 1.8 0.015 14.3 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) Cupin_8 PF13621.1 EME31676.1 - 5.4e-44 150.5 0.3 7.1e-44 150.1 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EME31676.1 - 9.7e-11 41.4 0.1 2.5e-10 40.1 0.1 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EME31676.1 - 0.00044 20.4 0.0 0.0014 18.8 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EME31676.1 - 0.0036 16.7 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain zf-RING_2 PF13639.1 EME31677.1 - 7e-13 48.1 12.6 7e-13 48.1 8.8 3.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME31677.1 - 2.7e-09 36.5 9.2 2.7e-09 36.5 6.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31677.1 - 3.7e-09 36.1 11.3 3.7e-09 36.1 7.9 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME31677.1 - 1.3e-08 34.6 14.0 1.3e-08 34.6 9.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME31677.1 - 1.7e-07 31.2 7.5 1.7e-07 31.2 5.2 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME31677.1 - 2.3e-07 30.3 13.6 2.3e-07 30.3 9.4 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME31677.1 - 0.011 15.3 8.0 0.048 13.3 5.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EME31677.1 - 0.022 14.3 6.8 0.066 12.7 4.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_3 PF14369.1 EME31677.1 - 0.024 14.6 8.4 0.024 14.6 5.9 3.3 3 1 0 3 3 3 0 zinc-finger Baculo_RING PF05883.6 EME31677.1 - 0.19 11.5 2.3 0.39 10.5 1.6 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 EME31677.1 - 0.66 9.8 13.7 0.11 12.2 4.5 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1244 PF06844.6 EME31677.1 - 0.97 9.3 3.6 0.54 10.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) zf-C3HC4_4 PF15227.1 EME31677.1 - 1.2 9.0 21.9 1.1 9.1 9.0 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EME31677.1 - 5 7.0 16.9 7.7 6.4 5.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.1 EME31677.1 - 7.6 6.4 11.8 0.15 11.8 3.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EME31678.1 - 7e-13 48.1 12.6 7e-13 48.1 8.8 3.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME31678.1 - 2.7e-09 36.5 9.2 2.7e-09 36.5 6.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31678.1 - 3.7e-09 36.1 11.3 3.7e-09 36.1 7.9 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME31678.1 - 1.3e-08 34.6 14.0 1.3e-08 34.6 9.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME31678.1 - 1.7e-07 31.2 7.5 1.7e-07 31.2 5.2 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME31678.1 - 2.3e-07 30.3 13.6 2.3e-07 30.3 9.4 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME31678.1 - 0.011 15.3 8.0 0.048 13.3 5.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EME31678.1 - 0.022 14.3 6.8 0.066 12.7 4.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_3 PF14369.1 EME31678.1 - 0.024 14.6 8.4 0.024 14.6 5.9 3.3 3 1 0 3 3 3 0 zinc-finger Baculo_RING PF05883.6 EME31678.1 - 0.19 11.5 2.3 0.39 10.5 1.6 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 EME31678.1 - 0.66 9.8 13.7 0.11 12.2 4.5 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1244 PF06844.6 EME31678.1 - 0.97 9.3 3.6 0.54 10.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) zf-C3HC4_4 PF15227.1 EME31678.1 - 1.2 9.0 21.9 1.1 9.1 9.0 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EME31678.1 - 5 7.0 16.9 7.7 6.4 5.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.1 EME31678.1 - 7.6 6.4 11.8 0.15 11.8 3.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Isy1 PF06246.7 EME31679.1 - 7.3e-79 264.7 10.0 8.3e-79 264.5 6.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Isy1 PF06246.7 EME31680.1 - 7.9e-64 215.5 8.3 8.9e-64 215.3 5.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family tRNA_synt_2f PF02092.12 EME31681.1 - 1.2e-165 552.2 0.0 1.5e-165 551.8 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.10 EME31681.1 - 2e-132 440.5 0.0 7.4e-132 438.6 0.0 1.9 2 0 0 2 2 2 1 Glycyl-tRNA synthetase alpha subunit Bromodomain PF00439.20 EME31682.1 - 3.2e-10 39.7 0.0 1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain Tctex-1 PF03645.8 EME31683.1 - 3.8e-32 110.1 3.1 4.9e-32 109.8 2.2 1.1 1 0 0 1 1 1 1 Tctex-1 family TPR_11 PF13414.1 EME31684.1 - 4e-32 109.6 7.4 6.5e-11 41.7 0.1 4.4 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 EME31684.1 - 1.4e-24 84.5 1.5 3.4e-05 23.2 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EME31684.1 - 7e-24 81.7 4.7 2.7e-06 26.8 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME31684.1 - 1.9e-16 60.2 8.5 4.2e-05 24.0 0.0 4.7 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME31684.1 - 2.2e-15 55.4 6.4 0.0031 17.5 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME31684.1 - 3.6e-15 55.6 6.5 9.1e-07 28.7 0.7 4.5 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME31684.1 - 1.2e-13 49.7 1.6 0.0058 16.3 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME31684.1 - 2.8e-13 49.2 9.0 0.022 15.3 0.1 6.8 3 2 5 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME31684.1 - 1.3e-09 38.2 2.1 0.016 15.5 0.0 4.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME31684.1 - 1.2e-08 34.8 2.6 0.65 10.5 0.1 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME31684.1 - 7e-08 31.7 3.7 1.1 9.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME31684.1 - 0.00068 19.4 6.3 0.34 10.7 0.1 4.4 3 2 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EME31684.1 - 0.00079 19.5 3.9 2.5 8.3 0.2 3.7 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EME31684.1 - 0.00079 18.2 0.0 0.4 9.3 0.0 2.7 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.17 EME31684.1 - 0.0015 17.7 0.6 0.0093 15.2 0.4 2.3 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.1 EME31684.1 - 0.028 14.3 0.8 22 5.0 0.0 3.6 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EME31684.1 - 0.11 12.7 2.6 2.4 8.4 0.1 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EME31684.1 - 8.4 6.4 7.4 1.3 9.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 EME31685.1 - 1.9e-84 283.6 0.1 2.5e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FANCI_S4 PF14678.1 EME31686.1 - 9.3e-21 74.0 2.3 9.3e-21 74.0 1.6 3.2 3 1 0 3 3 3 1 FANCI solenoid 4 FANCI_S2 PF14676.1 EME31686.1 - 2.4e-05 24.3 0.8 2.4e-05 24.3 0.6 3.5 3 1 1 4 4 4 1 FANCI solenoid 2 Elong_Iki1 PF10483.4 EME31687.1 - 0.013 14.8 0.4 0.08 12.2 0.1 2.0 1 1 1 2 2 2 0 Elongator subunit Iki1 Sec1 PF00995.18 EME31688.1 - 7e-77 259.3 4.4 1.6e-76 258.1 3.0 1.6 1 1 0 1 1 1 1 Sec1 family E1_dh PF00676.15 EME31691.1 - 1.2e-54 185.1 0.0 1.6e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 EME31691.1 - 1.7e-51 174.2 0.0 3.2e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain FHA PF00498.21 EME31693.1 - 3.6e-09 36.5 0.0 7.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain FH2 PF02181.18 EME31694.1 - 3.3e-83 279.6 10.2 3.3e-83 279.6 7.0 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Glyoxalase_2 PF12681.2 EME31695.1 - 9.8e-08 32.5 0.1 0.00035 21.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Rad60-SLD PF11976.3 EME31696.1 - 3.1e-18 65.2 0.0 3.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME31696.1 - 1.6e-08 33.8 0.0 2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1669 PF07894.7 EME31696.1 - 0.082 12.0 0.0 0.089 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) MMS1_N PF10433.4 EME31697.1 - 2.5e-11 42.4 2.3 1.9e-10 39.5 0.4 2.6 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EME31697.1 - 1.6e-07 30.7 0.0 9.6e-07 28.1 0.0 2.2 2 1 0 2 2 2 1 CPSF A subunit region ubiquitin PF00240.18 EME31698.1 - 2.8e-07 29.8 0.1 1.2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 EME31698.1 - 0.00057 20.0 0.6 0.0018 18.3 0.1 2.0 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain TP6A_N PF04406.9 EME31699.1 - 1.2e-09 37.6 0.2 2.5e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Sec1 PF00995.18 EME31700.1 - 5.8e-134 447.7 6.1 6.8e-134 447.5 4.2 1.0 1 0 0 1 1 1 1 Sec1 family Hemagglutinin PF00509.13 EME31700.1 - 0.0097 14.0 0.2 0.019 13.1 0.2 1.4 1 0 0 1 1 1 1 Haemagglutinin DUF4196 PF13846.1 EME31700.1 - 0.039 14.2 0.8 0.1 12.8 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) ABA_GPCR PF12430.3 EME31702.1 - 6.2e-29 100.5 13.2 6.2e-29 100.5 9.1 2.6 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EME31702.1 - 1.7e-08 34.3 0.1 3.6e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) FlaC_arch PF05377.6 EME31703.1 - 0.049 13.5 0.7 0.16 11.9 0.5 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Herpes_BLRF2 PF05812.7 EME31703.1 - 0.075 12.8 2.8 0.18 11.6 1.9 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Prefoldin_2 PF01920.15 EME31703.1 - 0.18 11.5 6.7 0.058 13.1 1.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit COG2 PF06148.6 EME31703.1 - 0.2 11.5 3.1 0.87 9.4 2.2 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EME31703.1 - 0.23 11.5 8.5 0.34 10.9 4.6 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 EME31703.1 - 0.74 9.3 5.8 1.4 8.5 4.0 1.5 1 0 0 1 1 1 0 IncA protein PspB PF06667.7 EME31703.1 - 1.2 9.1 3.6 1.6 8.7 0.2 2.5 2 0 0 2 2 2 0 Phage shock protein B HR1 PF02185.11 EME31703.1 - 1.6 8.5 10.1 0.1 12.3 0.9 2.7 2 0 0 2 2 2 0 Hr1 repeat DEAD PF00270.24 EME31704.1 - 6.9e-47 159.0 0.0 1.2e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME31704.1 - 1.7e-24 85.5 0.5 4.8e-24 84.0 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.7 EME31704.1 - 3.1e-07 30.3 0.0 6.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 EME31704.1 - 8.6e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RBFA PF02033.13 EME31705.1 - 1.7e-19 69.7 0.1 3e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A NIR_SIR_ferr PF03460.12 EME31705.1 - 0.039 13.5 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF3338 PF11819.3 EME31705.1 - 0.2 11.1 3.4 0.87 9.0 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) Filament PF00038.16 EME31706.1 - 0.00037 20.0 1.1 0.00071 19.1 0.8 1.4 1 0 0 1 1 1 1 Intermediate filament protein Sec8_exocyst PF04048.9 EME31706.1 - 0.00037 20.1 1.1 0.0058 16.2 0.5 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Mito_fiss_reg PF05308.6 EME31706.1 - 0.0045 16.3 1.0 0.0045 16.3 0.7 1.9 1 1 1 2 2 2 1 Mitochondrial fission regulator TBPIP PF07106.8 EME31706.1 - 0.011 15.3 5.3 0.2 11.1 1.7 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EME31706.1 - 0.012 15.1 1.3 0.029 13.9 0.9 1.6 1 0 0 1 1 1 0 IncA protein Erp_C PF06780.6 EME31706.1 - 0.021 14.6 1.1 0.33 10.7 0.8 2.4 2 0 0 2 2 2 0 Erp protein C-terminus TMF_DNA_bd PF12329.3 EME31706.1 - 0.025 14.3 0.6 0.094 12.5 0.4 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 EME31706.1 - 0.17 12.6 2.4 1.5 9.6 1.7 2.5 1 1 0 1 1 1 0 Occludin homology domain TPR_11 PF13414.1 EME31708.1 - 2.6e-19 68.6 0.1 1.3e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME31708.1 - 2.3e-15 55.4 0.2 9.1e-05 21.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME31708.1 - 1e-12 46.9 0.0 0.0043 16.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME31708.1 - 9.5e-11 40.6 0.3 0.0048 16.5 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME31708.1 - 5.2e-08 32.6 0.0 1.6e-06 27.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME31708.1 - 2.4e-07 31.2 0.0 9.6e-07 29.3 0.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME31708.1 - 1.9e-06 27.5 0.6 0.25 11.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME31708.1 - 7.2e-06 26.2 0.1 1.9e-05 24.8 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME31708.1 - 8.1e-06 25.6 0.1 0.0001 22.1 0.0 2.6 2 1 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EME31708.1 - 1.3e-05 25.2 5.8 0.0022 18.0 0.2 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EME31708.1 - 3.4e-05 23.3 0.0 0.026 14.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME31708.1 - 6e-05 23.3 0.0 0.04 14.5 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EME31708.1 - 0.00076 19.1 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 DnaJ domain TPR_6 PF13174.1 EME31708.1 - 0.00093 19.5 0.0 1.1 9.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.4 EME31708.1 - 0.0022 17.4 0.1 0.0075 15.6 0.1 1.9 1 1 0 1 1 1 1 26S proteasome subunit RPN7 NARP1 PF12569.3 EME31708.1 - 0.006 15.4 0.0 0.041 12.6 0.0 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 DUF2079 PF09852.4 EME31708.1 - 0.041 12.6 1.6 0.063 11.9 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) TPR_10 PF13374.1 EME31708.1 - 0.045 13.6 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EME31708.1 - 0.049 13.4 0.4 0.15 11.9 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EME31709.1 - 1e-15 57.2 4.5 2.2e-15 56.2 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EME31709.1 - 1.4e-13 50.3 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EME31709.1 - 5.3e-08 32.8 6.7 1.2e-07 31.6 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME31709.1 - 6.1e-08 32.5 5.7 1.2e-07 31.6 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31709.1 - 1e-06 28.3 3.6 1.8e-06 27.5 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME31709.1 - 2.6e-06 27.0 1.7 4.5e-06 26.2 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME31709.1 - 3.5e-06 26.5 5.1 6.8e-06 25.6 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME31709.1 - 0.0094 15.7 3.5 0.018 14.8 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EME31709.1 - 0.03 14.0 4.0 0.057 13.1 2.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EME31709.1 - 0.031 13.9 4.1 0.07 12.8 2.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EME31709.1 - 0.032 13.9 4.2 0.17 11.6 3.0 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EME31709.1 - 0.062 12.8 3.7 0.13 11.8 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EME31709.1 - 0.14 12.2 5.4 0.26 11.3 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME31709.1 - 0.14 12.1 4.2 0.54 10.2 2.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EME31709.1 - 0.2 11.5 3.0 0.51 10.2 2.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EME31709.1 - 0.22 11.0 1.3 0.46 10.0 0.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 EME31709.1 - 0.27 11.4 4.1 0.33 11.1 1.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING-like PF08746.6 EME31709.1 - 0.96 9.4 3.9 1.7 8.7 2.7 1.4 1 0 0 1 1 1 0 RING-like domain EMP70 PF02990.11 EME31710.1 - 3e-194 646.3 5.9 5e-194 645.5 4.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Zn_clus PF00172.13 EME31711.1 - 1.3e-06 28.1 6.2 2.8e-06 27.1 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_H_N PF03224.9 EME31712.1 - 0.015 14.4 1.9 0.025 13.6 0.5 1.9 2 0 0 2 2 2 0 V-ATPase subunit H Endonuc-HincII PF09226.6 EME31712.1 - 0.04 13.2 0.1 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease HincII Arm PF00514.18 EME31712.1 - 6.4 6.7 18.7 14 5.7 0.3 6.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Alpha-amylase PF00128.19 EME31713.1 - 7.4e-23 81.4 0.0 9.8e-16 58.0 0.0 3.2 2 1 0 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EME31713.1 - 1.2e-07 31.7 0.0 3.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glutaredoxin PF00462.19 EME31714.1 - 2.3e-22 78.7 0.1 3.2e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EME31714.1 - 2.1e-06 27.8 0.0 2.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME31714.1 - 0.0037 17.2 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EME31714.1 - 0.0088 16.2 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EME31714.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 EME31714.1 - 0.058 13.5 0.5 0.13 12.4 0.4 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DUF3567 PF12091.3 EME31714.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) DSBA PF01323.15 EME31714.1 - 0.26 10.7 1.8 3.5 7.1 0.4 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain VHS PF00790.14 EME31716.1 - 1.9e-05 24.3 0.1 0.0038 16.8 0.0 2.4 1 1 1 2 2 2 2 VHS domain Glyco_transf_20 PF00982.16 EME31717.1 - 1.7e-155 518.1 0.0 2.1e-155 517.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME31717.1 - 2.6e-63 213.0 0.0 4.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.14 EME31717.1 - 2.2e-17 62.4 0.0 8.8e-17 60.4 0.0 2.1 2 0 0 2 2 2 1 Starch binding domain Hydrolase_3 PF08282.7 EME31717.1 - 0.012 15.2 0.0 0.069 12.7 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_transf_20 PF00982.16 EME31718.1 - 1.7e-155 518.1 0.0 2.1e-155 517.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME31718.1 - 2.6e-63 213.0 0.0 4.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.14 EME31718.1 - 2.2e-17 62.4 0.0 8.8e-17 60.4 0.0 2.1 2 0 0 2 2 2 1 Starch binding domain Hydrolase_3 PF08282.7 EME31718.1 - 0.012 15.2 0.0 0.069 12.7 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rer1 PF03248.8 EME31719.1 - 4.9e-68 228.1 9.7 5.8e-68 227.9 6.7 1.1 1 0 0 1 1 1 1 Rer1 family zf-DHHC PF01529.15 EME31719.1 - 3.3 7.0 4.9 5.7 6.3 3.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pcc1 PF09341.5 EME31720.1 - 5e-16 58.4 0.1 6.5e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF2172 PF09940.4 EME31720.1 - 0.046 12.1 0.0 0.055 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Glyco_hydro_20b PF02838.10 EME31720.1 - 0.066 13.7 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Peptidase_S9 PF00326.16 EME31721.1 - 5.2e-34 117.3 0.0 7.6e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EME31721.1 - 2e-10 40.5 0.0 1.2e-08 34.7 0.0 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EME31721.1 - 6.8e-08 31.3 0.0 4.2e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 EME31721.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME31721.1 - 1.6e-05 24.9 0.0 3.8e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EME31721.1 - 4.9e-05 22.9 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EME31721.1 - 0.00017 21.2 0.1 0.098 12.1 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EME31721.1 - 0.00025 20.4 0.0 0.0013 18.0 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family zf-CCHC_4 PF14392.1 EME31721.1 - 0.0039 16.8 0.8 0.0086 15.7 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle BAAT_C PF08840.6 EME31721.1 - 0.0046 16.7 0.0 0.024 14.3 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EME31721.1 - 0.041 13.3 0.0 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EME31721.1 - 0.075 12.4 0.0 0.24 10.7 0.0 1.7 1 1 0 1 1 1 0 Putative esterase DUF3449 PF11931.3 EME31723.1 - 6.3e-63 211.8 1.7 6.3e-63 211.8 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 EME31723.1 - 5.6e-20 70.3 0.0 1.5e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 EME31723.1 - 0.014 14.9 0.3 0.032 13.7 0.2 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF3449 PF11931.3 EME31724.1 - 6.4e-63 211.8 1.7 6.4e-63 211.8 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 EME31724.1 - 5.7e-20 70.3 0.0 1.5e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 EME31724.1 - 0.014 14.9 0.3 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain RNA_pol_Rpb8 PF03870.10 EME31725.1 - 3.9e-37 127.4 0.1 5.9e-37 126.9 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb8 Swi3 PF07962.7 EME31726.1 - 1e-08 34.6 0.1 1.6e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 PRA-CH PF01502.13 EME31728.1 - 1.2e-34 117.7 0.3 2.1e-34 117.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase BBS2_Mid PF14783.1 EME31728.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PRA-CH PF01502.13 EME31729.1 - 1.2e-34 117.7 0.3 2.1e-34 117.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase BBS2_Mid PF14783.1 EME31729.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region LRR_6 PF13516.1 EME31730.1 - 5e-10 38.3 14.9 0.0022 17.8 0.0 6.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_8 PF13855.1 EME31730.1 - 0.058 13.1 5.1 9 6.1 2.1 3.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 EME31730.1 - 0.15 12.1 11.8 45 4.6 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat Trp_Tyr_perm PF03222.8 EME31731.1 - 2.8e-05 23.1 0.4 2.8e-05 23.1 0.3 2.7 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family PPR_2 PF13041.1 EME31732.1 - 7.5e-33 112.2 1.2 5.1e-11 42.3 0.1 7.1 4 2 4 8 8 8 6 PPR repeat family PPR PF01535.15 EME31732.1 - 2e-22 77.5 8.7 1.3e-07 31.0 0.1 8.7 9 0 0 9 9 9 3 PPR repeat PPR_3 PF13812.1 EME31732.1 - 2.3e-19 68.0 2.9 0.00036 20.5 0.0 7.6 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME31732.1 - 8.3e-17 60.3 4.0 1.8e-06 27.2 0.0 6.4 7 0 0 7 7 7 3 PPR repeat ATP13 PF12921.2 EME31732.1 - 0.018 14.3 0.1 1.8 7.9 0.0 2.7 1 1 1 2 2 2 0 Mitochondrial ATPase expression bZIP_2 PF07716.10 EME31733.1 - 0.00033 20.4 11.7 0.00033 20.4 8.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EME31733.1 - 0.0007 19.5 10.5 0.0007 19.5 7.3 2.5 2 0 0 2 2 2 1 bZIP transcription factor tRNA-synt_1d PF00750.14 EME31733.1 - 5.4 5.7 6.0 0.71 8.6 1.4 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (R) Lipoprotein_X PF03305.8 EME31733.1 - 7.5 5.8 13.4 61 2.8 9.3 2.0 1 1 0 1 1 1 0 Mycoplasma MG185/MG260 protein RWP-RK PF02042.10 EME31734.1 - 2.5e-22 78.4 0.3 4.4e-22 77.6 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_28 PF13518.1 EME31734.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Nop25 PF09805.4 EME31734.1 - 0.046 13.7 3.1 0.11 12.6 2.1 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Proteasome PF00227.21 EME31735.1 - 9.1e-40 135.9 0.0 1.1e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CoA_binding PF02629.14 EME31736.1 - 1e-28 99.6 1.9 1e-28 99.6 1.3 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EME31736.1 - 7.7e-21 74.2 0.2 1.6e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EME31736.1 - 6.8e-08 32.2 0.2 1.3e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EME31736.1 - 3.5e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.15 EME31736.1 - 0.0021 17.9 0.4 0.0052 16.6 0.3 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EME31736.1 - 0.0064 16.9 0.1 0.015 15.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-CSL PF05207.8 EME31737.1 - 1.3e-23 82.2 0.9 1.7e-23 81.8 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger DUF164 PF02591.10 EME31737.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain UPF0547 PF10571.4 EME31737.1 - 1.5 8.5 4.1 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF1664 PF07889.7 EME31738.1 - 1.1e-13 51.1 1.2 7.1e-13 48.4 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.13 EME31738.1 - 2.3e-05 24.0 2.5 9.2e-05 22.0 0.3 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EME31738.1 - 2.4e-05 24.1 0.7 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 EME31738.1 - 6.9e-05 22.9 5.6 0.016 15.3 0.1 2.7 2 1 0 2 2 2 2 Syntaxin Filament PF00038.16 EME31738.1 - 0.00082 18.9 3.7 0.00085 18.8 0.3 2.0 2 0 0 2 2 2 1 Intermediate filament protein AAA_32 PF13654.1 EME31738.1 - 0.003 16.3 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain WXG100 PF06013.7 EME31738.1 - 0.026 14.5 2.7 6.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Spc7 PF08317.6 EME31738.1 - 0.046 12.3 2.0 0.13 10.9 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1843 PF08898.5 EME31738.1 - 0.11 12.4 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Rogdi_lz PF10259.4 EME31738.1 - 0.13 11.3 1.8 7 5.6 0.1 2.8 2 1 1 3 3 3 0 Rogdi leucine zipper containing protein BLOC1_2 PF10046.4 EME31738.1 - 0.14 12.3 3.8 0.63 10.2 0.9 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 EME31738.1 - 0.14 11.3 6.2 0.09 11.9 0.8 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 EME31738.1 - 0.15 10.7 4.4 0.094 11.4 0.4 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HsbA PF12296.3 EME31738.1 - 0.29 11.0 2.4 2.5 7.9 0.5 2.7 3 0 0 3 3 3 0 Hydrophobic surface binding protein A IncA PF04156.9 EME31738.1 - 0.31 10.6 8.8 2.2 7.8 2.2 2.8 2 1 0 2 2 2 0 IncA protein COG5 PF10392.4 EME31738.1 - 0.48 10.3 5.0 8.4 6.3 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 MbeD_MobD PF04899.7 EME31738.1 - 1.3 8.9 5.3 6.2 6.7 0.1 3.2 2 1 1 3 3 3 0 MbeD/MobD like COG2 PF06148.6 EME31738.1 - 2.2 8.1 8.0 22 4.9 0.6 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Plus-3 PF03126.13 EME31739.1 - 5.8e-22 77.7 0.0 2.6e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain Nol1_Nop2_Fmu PF01189.12 EME31740.1 - 1.1e-32 113.5 0.0 9.9e-23 80.9 0.0 3.1 3 0 0 3 3 3 2 NOL1/NOP2/sun family FtsJ PF01728.14 EME31740.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Nol1_Nop2_Fmu PF01189.12 EME31741.1 - 9.2e-33 113.8 0.0 8.7e-23 81.0 0.0 3.1 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EME31741.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPRTase PF14681.1 EME31742.1 - 3.9e-57 192.7 0.0 5.6e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EME31742.1 - 4.4e-45 153.6 0.0 6.7e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EME31742.1 - 2.9e-06 28.0 0.1 1.4e-05 25.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME31742.1 - 4.2e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Pribosyltran PF00156.22 EME31742.1 - 0.00024 20.8 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_19 PF13245.1 EME31742.1 - 0.00096 18.8 0.2 0.89 9.3 0.1 2.5 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 EME31742.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EME31742.1 - 0.018 14.9 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME31742.1 - 0.04 13.6 0.1 0.2 11.3 0.1 2.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EME31742.1 - 0.044 12.6 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EME31742.1 - 0.096 12.3 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PRTase_2 PF15609.1 EME31742.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CoaE PF01121.15 EME31742.1 - 0.15 11.4 0.7 0.32 10.3 0.1 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase Hemerythrin PF01814.18 EME31743.1 - 9.4e-12 45.2 3.4 1.4e-11 44.6 2.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DSX_dimer PF08828.5 EME31743.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain DUF924 PF06041.6 EME31744.1 - 3.3e-57 193.2 4.8 4e-57 193.0 3.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF1886 PF09171.5 EME31744.1 - 0.016 14.2 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) UPF0020 PF01170.13 EME31745.1 - 5.2e-09 35.9 0.0 2.7e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EME31745.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain YSIRK_signal PF04650.12 EME31745.1 - 0.69 9.5 2.9 1.7 8.2 2.0 1.7 1 0 0 1 1 1 0 YSIRK type signal peptide FMN_dh PF01070.13 EME31746.1 - 8.9e-134 445.8 0.2 1e-133 445.6 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EME31746.1 - 1.1e-05 24.6 2.2 0.078 12.0 0.1 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EME31746.1 - 3.7e-05 22.7 4.6 0.0012 17.8 1.3 3.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EME31746.1 - 0.00016 21.0 1.5 0.0091 15.2 0.0 2.7 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 EME31746.1 - 0.00064 18.9 2.5 0.0012 18.0 1.8 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EME31746.1 - 0.004 16.1 0.2 0.0067 15.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 EME31746.1 - 0.11 11.5 0.1 0.42 9.6 0.1 1.9 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Dus PF01207.12 EME31746.1 - 0.11 11.2 0.9 0.45 9.2 0.4 2.1 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EME31746.1 - 0.33 9.8 2.1 5.3 5.9 0.1 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase HAMP PF00672.20 EME31748.1 - 0.045 13.9 2.3 1.2 9.4 1.6 2.3 1 1 0 1 1 1 0 HAMP domain Tektin PF03148.9 EME31748.1 - 0.048 12.2 14.2 0.071 11.6 9.8 1.2 1 0 0 1 1 1 0 Tektin family NICE-3 PF07406.6 EME31748.1 - 0.06 12.8 2.0 0.091 12.2 1.4 1.3 1 0 0 1 1 1 0 NICE-3 protein DUF724 PF05266.9 EME31748.1 - 0.098 12.2 6.5 0.15 11.6 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EF1_GNE PF00736.14 EME31748.1 - 0.15 11.7 5.0 1.1 9.0 0.4 2.9 1 1 2 3 3 3 0 EF-1 guanine nucleotide exchange domain Atg14 PF10186.4 EME31748.1 - 0.17 10.7 8.6 0.24 10.3 5.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF843 PF05814.6 EME31748.1 - 0.31 10.8 1.6 0.46 10.3 0.5 1.8 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3450 PF11932.3 EME31748.1 - 0.33 10.1 8.1 0.18 11.0 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rabaptin PF03528.10 EME31748.1 - 0.52 10.2 16.1 9.9 6.1 11.2 2.2 1 1 0 1 1 1 0 Rabaptin Bacillus_HBL PF05791.6 EME31748.1 - 0.56 9.5 8.6 0.091 12.1 0.9 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TelA PF05816.6 EME31748.1 - 1.1 7.9 11.3 3.2 6.3 4.4 2.0 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DivIC PF04977.10 EME31748.1 - 1.6 8.3 11.8 0.81 9.2 4.3 2.4 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EME31748.1 - 2.1 8.3 9.0 1.5 8.7 1.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 EME31748.1 - 3.3 7.4 23.5 2.3 7.9 3.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EME31748.1 - 4.9 7.0 6.0 6.8 6.6 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EME31748.1 - 5.2 4.8 9.7 7 4.3 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACCA PF03255.9 EME31748.1 - 5.3 6.5 8.9 10 5.6 0.7 2.4 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit B-block_TFIIIC PF04182.7 EME31750.1 - 3.5e-11 42.8 1.2 8.4e-06 25.5 0.2 4.3 4 0 0 4 4 4 2 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EME31750.1 - 4.4e-08 32.6 1.1 0.068 12.8 0.0 4.5 4 0 0 4 4 4 2 MarR family MarR PF01047.17 EME31750.1 - 3.4e-07 29.8 4.7 0.34 10.6 0.0 5.3 5 0 0 5 5 5 2 MarR family HTH_20 PF12840.2 EME31750.1 - 2.3e-05 24.0 1.2 0.061 13.1 0.1 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_24 PF13412.1 EME31750.1 - 0.00016 20.9 4.4 0.49 9.8 0.0 5.3 6 0 0 6 6 6 2 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EME31750.1 - 0.00088 19.3 2.2 1.2 9.3 0.1 3.8 4 0 0 4 4 4 2 Transcriptional regulator HTH_36 PF13730.1 EME31750.1 - 0.0013 18.8 0.0 3.1 7.9 0.0 3.6 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.14 EME31750.1 - 0.0029 17.2 0.3 0.57 9.9 0.0 3.5 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 EME31750.1 - 0.099 12.2 2.8 3 7.5 0.0 4.1 4 0 0 4 4 4 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.1 EME31750.1 - 2.9 7.7 5.6 74 3.2 0.0 4.4 4 0 0 4 4 4 0 Crp-like helix-turn-helix domain NRDE-2 PF08424.5 EME31751.1 - 8.7e-25 87.2 0.3 1.7e-24 86.2 0.2 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference PEX11 PF05648.9 EME31752.1 - 0.00044 19.5 0.9 0.00079 18.7 0.1 1.7 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Apc5 PF12862.2 EME31753.1 - 6.1e-10 38.8 0.4 7e-09 35.4 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 EME31753.1 - 0.14 12.5 0.8 41 4.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EME31754.1 - 5.9e-34 117.9 0.1 7.4e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME31754.1 - 1.4e-18 67.0 0.0 1.2e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME31754.1 - 1.5e-13 50.8 0.0 4.6e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME31754.1 - 2.6e-07 30.4 0.0 5.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EME31754.1 - 6.8e-07 28.0 0.0 1.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 EME31754.1 - 4e-06 26.4 0.1 0.0087 15.5 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EME31754.1 - 5.9e-06 25.3 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EME31754.1 - 6.4e-05 23.2 0.0 0.00017 21.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase PF07224.6 EME31754.1 - 0.00088 18.1 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.8 EME31754.1 - 0.0025 17.4 0.0 0.0077 15.8 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase DUF2305 PF10230.4 EME31754.1 - 0.0055 16.1 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EME31754.1 - 0.0062 15.9 0.1 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 Putative esterase DUF3665 PF12427.3 EME31754.1 - 0.0093 15.2 0.2 0.15 11.4 0.1 2.5 2 0 0 2 2 2 1 Branched-chain amino acid aminotransferase FSH1 PF03959.8 EME31754.1 - 0.036 13.5 0.0 8.1 5.8 0.0 2.8 3 0 0 3 3 3 0 Serine hydrolase (FSH1) DUF3530 PF12048.3 EME31754.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DLH PF01738.13 EME31754.1 - 0.15 11.2 0.0 1.3 8.2 0.0 2.4 3 1 0 3 3 3 0 Dienelactone hydrolase family PhzC-PhzF PF02567.11 EME31755.1 - 5.2e-52 176.8 0.0 6.4e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Helicase_Sgs1 PF11408.3 EME31755.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase PfkB PF00294.19 EME31756.1 - 1.4e-44 152.4 0.0 3.6e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Amino_oxidase PF01593.19 EME31757.1 - 6.2e-83 279.3 0.0 1e-82 278.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME31757.1 - 3e-15 55.9 0.0 6.9e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ARID PF01388.16 EME31757.1 - 1e-14 54.1 0.0 2.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SWIRM PF04433.12 EME31757.1 - 5.8e-08 32.7 0.0 1.5e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain DAO PF01266.19 EME31757.1 - 2.2e-06 26.8 0.1 4.2e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME31757.1 - 4.5e-06 26.9 0.3 1.4e-05 25.3 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31757.1 - 1.1e-05 24.7 0.1 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME31757.1 - 1.2e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME31757.1 - 1.5e-05 24.9 0.3 3.8e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME31757.1 - 0.00017 21.6 0.1 0.00037 20.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME31757.1 - 0.00022 20.4 0.5 0.00035 19.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME31757.1 - 0.00031 19.7 0.5 0.00048 19.0 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME31757.1 - 0.00039 18.9 0.2 0.00039 18.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EME31757.1 - 0.00065 19.3 0.2 0.0017 17.9 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EME31757.1 - 0.0012 17.7 0.2 0.0021 16.9 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME31757.1 - 0.0019 17.9 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME31757.1 - 0.18 10.6 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EME31757.1 - 0.26 10.9 0.6 1.2 8.7 0.0 2.5 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EME31758.1 - 8.9e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31758.1 - 1.2e-10 40.9 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EME31758.1 - 1.1e-09 37.5 1.1 0.049 13.7 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EME31758.1 - 0.00047 20.5 0.0 0.012 16.1 0.0 3.0 2 1 1 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 EME31758.1 - 0.0017 18.5 0.0 0.023 14.9 0.0 2.8 2 2 0 2 2 2 1 HEAT repeats DUF2435 PF10363.4 EME31758.1 - 0.019 14.8 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 EME31758.1 - 0.075 13.4 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Catalase PF00199.14 EME31759.1 - 8.4e-172 571.1 0.0 9.7e-172 570.9 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EME31759.1 - 7.7e-19 67.3 0.1 2.2e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive UCH PF00443.24 EME31760.1 - 1.6e-74 250.4 1.3 1.7e-74 250.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EME31760.1 - 3.4e-25 88.3 0.1 1.6e-24 86.2 0.1 2.2 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 EME31760.1 - 1.7e-19 70.3 0.0 9e-10 38.4 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SynMuv_product PF06047.6 EME31761.1 - 3.3e-10 39.6 1.6 5.1e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Ras-induced vulval development antagonist Rib_recp_KP_reg PF05104.7 EME31761.1 - 0.017 15.6 0.5 0.025 15.0 0.4 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region SAP PF02037.22 EME31763.1 - 4.4e-14 51.5 2.8 1.1e-13 50.3 1.9 1.7 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EME31763.1 - 0.057 12.9 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain 2-Hacid_dh_C PF02826.14 EME31764.1 - 1.7e-51 173.9 0.0 3.2e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME31764.1 - 2.1e-37 127.5 0.0 3.4e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME31764.1 - 3.9e-07 30.0 0.0 1.1e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EME31764.1 - 7.3e-06 25.3 0.2 1.8e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 EME31764.1 - 0.0094 15.8 0.1 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EME31764.1 - 0.088 12.4 0.1 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EME31764.1 - 0.098 12.0 0.1 0.49 9.7 0.1 2.1 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EME31764.1 - 0.15 11.4 1.2 0.28 10.5 0.2 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_N PF08240.7 EME31765.1 - 4.4e-28 97.2 0.8 7.6e-28 96.4 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME31765.1 - 9.4e-09 34.9 0.6 2.2e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EME31765.1 - 4.2e-08 32.6 0.4 1e-07 31.4 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EME31765.1 - 5.8e-06 25.0 0.2 5e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EME31765.1 - 0.012 15.1 0.2 0.028 14.0 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EME31765.1 - 0.024 13.5 0.4 0.035 13.0 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME31765.1 - 0.045 14.1 0.3 0.098 13.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME31765.1 - 0.046 12.5 0.1 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EME31765.1 - 0.067 13.3 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EME31765.1 - 0.083 11.9 0.5 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME31765.1 - 0.087 11.8 0.2 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Myb_DNA-binding PF00249.26 EME31766.1 - 0.00073 19.5 0.5 0.00073 19.5 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain NAD_binding_5 PF07994.7 EME31767.1 - 1.6e-117 392.2 0.0 1.9e-117 391.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EME31767.1 - 1.9e-44 150.0 0.2 3.6e-44 149.1 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase RED_C PF07807.6 EME31767.1 - 0.15 12.2 2.3 0.2 11.8 0.5 1.8 2 0 0 2 2 2 0 RED-like protein C-terminal region BACK PF07707.10 EME31768.1 - 8.9e-16 57.6 1.1 8.9e-16 57.6 0.8 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 EME31768.1 - 1.1e-10 41.4 0.1 1.1e-10 41.4 0.1 3.0 4 0 0 4 4 4 1 BTB/POZ domain Methyltransf_FA PF12248.3 EME31768.1 - 3.1e-06 27.1 0.0 1.3e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Farnesoic acid 0-methyl transferase F5_F8_type_C PF00754.20 EME31768.1 - 3.1e-05 23.7 0.0 9.4e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.10 EME31769.1 - 9.1e-16 57.5 1.1 9.1e-16 57.5 0.8 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.26 EME31769.1 - 7.6e-11 41.9 4.2 1.2e-10 41.3 0.1 2.9 3 0 0 3 3 3 1 BTB/POZ domain Methyltransf_FA PF12248.3 EME31769.1 - 3.2e-06 27.0 0.0 1.3e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Farnesoic acid 0-methyl transferase F5_F8_type_C PF00754.20 EME31769.1 - 3.2e-05 23.7 0.0 9.6e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain GHMP_kinases_N PF00288.21 EME31770.1 - 1.2e-10 41.2 7.7 1.3e-10 41.1 2.6 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME31770.1 - 6e-06 26.3 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GIT_SHD PF08518.6 EME31770.1 - 0.053 12.8 0.9 0.14 11.5 0.6 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT CK_II_beta PF01214.13 EME31771.1 - 9.7e-76 253.3 0.0 1.1e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-RING_2 PF13639.1 EME31773.1 - 1.3e-12 47.3 8.5 3.8e-12 45.8 5.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME31773.1 - 2.8e-06 27.3 6.4 9.3e-06 25.6 4.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME31773.1 - 3e-05 23.5 8.4 3e-05 23.5 5.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31773.1 - 6.9e-05 22.7 7.9 6.9e-05 22.7 5.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31773.1 - 7.1e-05 22.3 5.0 7.1e-05 22.3 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME31773.1 - 0.00087 19.0 1.5 0.0018 18.0 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME31773.1 - 0.0026 17.4 6.7 0.0026 17.4 4.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Claudin_2 PF13903.1 EME31773.1 - 0.029 14.0 0.1 0.029 14.0 0.1 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction GAGA PF09237.6 EME31773.1 - 0.049 13.2 0.8 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 GAGA factor RINGv PF12906.2 EME31773.1 - 0.061 13.3 8.0 0.17 11.9 5.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EME31773.1 - 0.15 11.6 6.7 2.8 7.5 5.2 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EME31773.1 - 0.17 11.8 6.0 2 8.4 4.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain NUDIX PF00293.23 EME31774.1 - 1.6e-19 69.9 0.0 2.1e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EME31774.1 - 0.00048 19.5 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EME31775.1 - 1.3e-19 70.1 0.0 1.7e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EME31775.1 - 0.00042 19.7 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1e PF01406.14 EME31776.1 - 2.2e-118 394.7 0.1 4.3e-118 393.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EME31776.1 - 8.9e-12 44.3 1.0 3.9e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EME31776.1 - 1.5e-06 26.5 0.0 1.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EME31776.1 - 0.019 15.2 0.2 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 DALR domain zf-C3HC4 PF00097.20 EME31777.1 - 3.8e-09 36.0 9.6 3.8e-09 36.0 6.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME31777.1 - 1.5e-08 34.2 9.0 1.5e-08 34.2 6.2 2.9 3 0 0 3 3 3 1 Ring finger domain SAP PF02037.22 EME31777.1 - 1.3e-07 30.9 0.0 3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.1 EME31777.1 - 1.7e-07 31.1 10.6 1.7e-07 31.1 7.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31777.1 - 1.4e-06 27.8 11.6 6.3e-06 25.7 5.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31777.1 - 1.5e-06 27.8 8.4 1.5e-06 27.8 5.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME31777.1 - 5e-06 26.5 4.9 5e-06 26.5 3.4 3.2 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EME31777.1 - 5e-05 23.0 5.4 5e-05 23.0 3.7 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EME31777.1 - 0.0001 21.9 7.1 0.0001 21.9 4.9 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EME31777.1 - 0.00012 21.8 4.6 0.00094 18.9 2.4 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PRP21_like_P PF12230.3 EME31777.1 - 0.0002 20.9 1.0 0.0002 20.9 0.7 1.8 2 0 0 2 2 1 1 Pre-mRNA splicing factor PRP21 like protein zf-C3HC4_4 PF15227.1 EME31777.1 - 0.00054 19.7 9.2 0.00054 19.7 6.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3405 PF11885.3 EME31777.1 - 0.0026 16.0 0.1 0.004 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) zf-Nse PF11789.3 EME31777.1 - 0.0086 15.5 3.6 0.0086 15.5 2.5 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.21 EME31777.1 - 0.011 16.0 3.9 0.07 13.4 0.0 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.10 EME31777.1 - 0.025 14.3 2.6 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 BED zinc finger FYVE PF01363.16 EME31777.1 - 0.027 14.3 11.5 0.48 10.3 2.3 3.2 3 0 0 3 3 3 0 FYVE zinc finger zf-C2HC_2 PF13913.1 EME31777.1 - 0.12 12.1 6.9 0.48 10.1 0.1 3.1 2 1 0 2 2 2 0 zinc-finger of a C2HC-type Elf1 PF05129.8 EME31777.1 - 0.68 9.6 10.1 1.2 8.8 2.3 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 EME31777.1 - 2.6 7.9 8.8 1.3 8.8 2.7 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.15 EME31777.1 - 3.1 7.3 12.0 3.9 7.0 5.7 2.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Eapp_C PF10238.4 EME31777.1 - 3.2 7.6 8.6 0.11 12.4 0.4 2.5 2 1 0 2 2 2 0 E2F-associated phosphoprotein zf-H2C2_2 PF13465.1 EME31777.1 - 6.9 7.1 0.0 6.9 7.1 0.0 3.3 4 0 0 4 4 2 0 Zinc-finger double domain Peptidase_S49 PF01343.13 EME31778.1 - 2e-59 199.8 0.0 6.8e-41 139.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 UQ_con PF00179.21 EME31779.1 - 7.8e-51 171.1 0.0 8.8e-51 171.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME31779.1 - 3.7e-06 26.7 0.0 4.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME31779.1 - 0.032 14.1 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain ABC1 PF03109.11 EME31783.1 - 7.4e-29 100.1 0.0 1.4e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family DnaJ_CXXCXGXG PF00684.14 EME31784.1 - 7.8e-05 22.6 11.0 7.8e-05 22.6 7.6 2.5 2 1 1 3 3 3 2 DnaJ central domain DUF1356 PF07092.7 EME31784.1 - 4.3 6.4 10.0 6.9 5.7 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_3 PF14369.1 EME31784.1 - 5.4 7.0 14.0 2.5 8.1 0.3 3.8 2 2 2 4 4 4 0 zinc-finger Gar1 PF04410.9 EME31785.1 - 2.5e-31 108.2 0.1 4.4e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Dus PF01207.12 EME31786.1 - 4.1e-58 196.6 0.0 7.2e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 EME31786.1 - 0.024 13.8 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase WD40 PF00400.27 EME31787.1 - 2.7e-36 122.1 7.3 6.7e-09 35.2 0.3 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EME31787.1 - 2.5e-08 33.8 0.1 3.5e-05 23.5 0.1 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EME31787.1 - 0.0015 17.9 0.0 11 5.6 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 EME31787.1 - 0.014 13.7 0.0 1.4 7.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain GSP_synth PF03738.9 EME31787.1 - 0.062 13.5 0.0 0.6 10.4 0.0 2.5 2 2 2 4 4 4 0 Glutathionylspermidine synthase preATP-grasp CR6_interact PF10147.4 EME31788.1 - 0.00013 21.3 6.4 0.00013 21.3 4.5 1.3 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4460 PF14687.1 EME31788.1 - 0.087 12.5 1.8 0.14 11.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) PRKCSH-like PF12999.2 EME31789.1 - 2.5e-43 147.6 3.6 6.4e-43 146.3 2.5 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EME31789.1 - 6.8e-34 116.5 0.3 2.4e-33 114.7 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EME31789.1 - 0.008 16.0 15.1 0.068 13.0 3.0 2.8 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A THOC7 PF05615.8 EME31789.1 - 7.5 6.8 10.4 1.7 8.8 0.3 3.1 3 0 0 3 3 3 0 Tho complex subunit 7 STAG PF08514.6 EME31790.1 - 3.1e-07 30.1 2.1 3.1e-07 30.1 1.5 3.2 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 EME31790.1 - 0.037 14.1 0.1 6.2 7.1 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat DUF1542 PF07564.6 EME31790.1 - 5.2 7.1 7.3 0.69 9.9 1.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DnaJ PF00226.26 EME31792.1 - 3e-23 81.3 0.2 8.5e-23 79.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain DUF3395 PF11875.3 EME31792.1 - 9.7e-22 77.2 0.1 1.5e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DUF3395 PF11875.3 EME31793.1 - 5.9e-29 100.6 0.0 8.9e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EME31793.1 - 3.3e-23 81.1 0.2 9.1e-23 79.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Hist_deacetyl PF00850.14 EME31795.1 - 2.4e-75 253.7 0.1 3.8e-75 253.0 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain SNAP PF14938.1 EME31796.1 - 1.4e-98 329.5 23.0 1.5e-98 329.4 15.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EME31796.1 - 5.2e-08 32.7 11.5 0.00079 19.3 1.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME31796.1 - 2.1e-05 23.9 10.5 0.0021 17.7 0.2 5.2 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME31796.1 - 5.1e-05 22.8 13.4 0.023 14.5 0.1 6.4 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME31796.1 - 7.2e-05 22.3 17.5 0.00061 19.3 0.5 3.7 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.1 EME31796.1 - 0.00013 21.4 5.2 0.00041 19.9 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EME31796.1 - 0.0022 18.3 13.6 0.65 10.5 0.1 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME31796.1 - 0.0071 15.9 10.9 0.06 12.9 0.2 4.4 5 1 0 5 5 3 1 Tetratricopeptide repeat DUF3366 PF11846.3 EME31796.1 - 0.01 15.7 3.3 0.023 14.5 1.3 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) Foie-gras_1 PF11817.3 EME31796.1 - 0.018 14.5 5.2 0.14 11.5 3.6 2.4 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_14 PF13428.1 EME31796.1 - 0.028 15.0 12.5 3 8.7 0.0 5.3 2 2 3 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EME31796.1 - 0.058 12.7 7.6 1.5 8.1 0.1 3.4 1 1 2 3 3 3 0 26S proteasome subunit RPN7 NSF PF02071.15 EME31796.1 - 0.076 13.5 21.7 1.6 9.6 0.5 7.0 7 1 0 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat Rapamycin_bind PF08771.6 EME31796.1 - 0.21 11.7 4.3 0.36 10.9 0.6 2.7 1 1 1 2 2 2 0 Rapamycin binding domain DUF2937 PF11157.3 EME31796.1 - 0.3 10.4 3.1 5.8 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) HHH_8 PF14716.1 EME31796.1 - 0.52 10.5 4.9 1.5 9.0 0.1 3.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF2225 PF09986.4 EME31796.1 - 0.53 9.7 8.7 0.099 12.0 1.2 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Spatacsin_C PF14649.1 EME31796.1 - 1.2 7.9 8.4 1.7 7.4 2.3 2.7 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_16 PF13432.1 EME31796.1 - 1.7 9.4 23.1 0.091 13.4 1.4 4.9 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME31796.1 - 4.1 7.8 16.4 0.85 10.0 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EME31796.1 - 6.1 7.0 10.6 0.8 9.8 0.9 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FAD_binding_7 PF03441.9 EME31798.1 - 6.7e-50 169.8 0.0 9.5e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME31798.1 - 7.2e-22 77.8 0.5 1.5e-21 76.8 0.1 1.8 2 0 0 2 2 2 1 DNA photolyase SieB PF14163.1 EME31799.1 - 0.035 13.6 3.5 0.064 12.8 2.4 1.6 1 1 0 1 1 1 0 Superinfection exclusion protein B Latrotoxin_C PF15658.1 EME31799.1 - 0.069 12.9 0.8 1.4 8.7 0.0 2.3 2 1 0 2 2 2 0 Latrotoxin C-terminal domain DUF2681 PF10883.3 EME31799.1 - 5.9 7.1 9.9 12 6.1 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Myb_DNA-bind_4 PF13837.1 EME31799.1 - 7.8 6.7 8.6 11 6.2 0.3 3.2 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Glyco_transf_64 PF09258.5 EME31800.1 - 1.7e-62 210.8 0.1 2.8e-62 210.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.15 EME31800.1 - 1.1e-31 110.0 3.0 2.3e-31 109.0 1.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EME31800.1 - 1.3e-05 25.1 1.0 2.5e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glycos_transf_2 PF00535.21 EME31800.1 - 4.3e-05 23.2 1.9 0.11 12.1 0.0 3.4 4 0 0 4 4 4 2 Glycosyl transferase family 2 Mannosyl_trans3 PF11051.3 EME31800.1 - 0.016 14.5 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_21 PF13506.1 EME31800.1 - 0.072 12.3 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_transf_64 PF09258.5 EME31801.1 - 1.6e-60 204.3 0.1 2.6e-60 203.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.15 EME31801.1 - 1.8e-31 109.4 3.5 2.3e-31 109.0 1.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EME31801.1 - 1.1e-05 25.2 1.0 2.5e-05 24.1 0.7 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glycos_transf_2 PF00535.21 EME31801.1 - 0.00014 21.5 2.8 0.2 11.3 0.1 3.5 4 0 0 4 4 4 2 Glycosyl transferase family 2 Mannosyl_trans3 PF11051.3 EME31801.1 - 0.017 14.5 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Dor1 PF04124.7 EME31803.1 - 5.5e-35 120.4 6.5 7.7e-35 119.9 4.5 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EME31803.1 - 0.00035 20.5 1.4 0.00035 20.5 1.0 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EME31803.1 - 0.0057 16.4 0.8 0.027 14.3 0.5 2.2 1 1 0 1 1 1 1 Vps51/Vps67 Branch PF02485.16 EME31804.1 - 1.9e-27 95.9 0.1 2.8e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TRAPP PF04051.11 EME31805.1 - 2.1e-29 102.0 0.0 2.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pkinase PF00069.20 EME31806.1 - 6.7e-55 186.0 0.0 8.7e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31806.1 - 2.8e-54 183.9 0.0 3.3e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31806.1 - 0.00013 21.8 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME31806.1 - 0.00014 20.9 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME31806.1 - 0.032 13.2 0.0 0.073 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_2 PF12706.2 EME31807.1 - 1.7e-22 79.9 0.3 3.3e-21 75.7 0.2 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME31807.1 - 1.1e-08 34.9 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FUSC_2 PF13515.1 EME31808.1 - 8.9e-07 28.8 18.2 8.9e-07 28.8 12.6 3.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EME31808.1 - 0.0034 16.0 1.1 0.0034 16.0 0.8 2.3 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF647 PF04884.9 EME31810.1 - 3e-78 262.4 0.1 4.5e-78 261.8 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Met_gamma_lyase PF06838.6 EME31810.1 - 0.14 10.4 0.1 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DUF1674 PF07896.7 EME31811.1 - 7.3e-11 42.1 4.5 1.1e-10 41.5 3.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) ABC_tran PF00005.22 EME31812.1 - 4e-29 101.6 0.0 7e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME31812.1 - 4.2e-07 30.2 0.1 1.6e-05 25.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME31812.1 - 8.6e-05 22.0 0.0 0.00035 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EME31812.1 - 0.0013 18.1 0.1 0.092 12.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EME31812.1 - 0.0013 19.5 0.0 0.0038 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 EME31812.1 - 0.0018 17.5 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EME31812.1 - 0.0031 16.7 0.2 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EME31812.1 - 0.0091 15.0 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EME31812.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EME31812.1 - 0.015 14.7 0.9 0.53 9.7 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME31812.1 - 0.016 14.6 0.1 0.068 12.7 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME31812.1 - 0.019 15.1 0.1 0.068 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME31812.1 - 0.022 15.0 0.0 0.083 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EME31812.1 - 0.038 13.9 0.6 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 EME31812.1 - 0.044 12.3 0.1 0.19 10.2 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EME31812.1 - 0.054 13.4 0.5 0.39 10.6 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME31812.1 - 0.056 13.2 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EME31812.1 - 0.057 12.3 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EME31812.1 - 0.061 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EME31812.1 - 0.064 13.1 0.3 0.39 10.5 0.2 2.3 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EME31812.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.7 EME31812.1 - 0.13 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EME31812.1 - 0.14 12.3 0.1 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane PF01061.19 EME31813.1 - 3e-39 134.3 27.2 4.3e-39 133.8 18.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME31813.1 - 7.4e-29 100.8 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME31813.1 - 7.5e-07 29.3 0.8 2.5e-05 24.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME31813.1 - 0.00016 21.1 0.0 0.00051 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME31813.1 - 0.0024 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EME31813.1 - 0.0026 17.1 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EME31813.1 - 0.0027 18.5 0.0 0.0054 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EME31813.1 - 0.0059 15.8 0.2 0.4 9.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EME31813.1 - 0.011 14.8 25.5 0.018 14.1 17.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_15 PF13175.1 EME31813.1 - 0.017 14.1 0.0 0.5 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EME31813.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME31813.1 - 0.031 14.4 0.1 0.098 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME31813.1 - 0.034 13.6 0.1 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EME31813.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME31813.1 - 0.076 12.9 0.6 0.16 11.9 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 EME31813.1 - 0.079 11.5 0.1 0.27 9.7 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T2SE PF00437.15 EME31813.1 - 0.082 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EME31813.1 - 0.083 12.6 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SbcCD_C PF13558.1 EME31813.1 - 0.098 12.5 0.5 0.54 10.2 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EME31813.1 - 0.1 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EME31813.1 - 0.13 12.1 0.3 0.57 10.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EME31813.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Dynamin family cobW PF02492.14 EME31813.1 - 0.23 10.9 0.3 0.7 9.3 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_2 PF12679.2 EME31813.1 - 0.28 10.0 13.5 0.0094 14.8 5.0 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EME31814.1 - 7.1e-17 61.2 12.4 1.1e-16 60.6 8.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.2 EME31814.1 - 4e-05 22.6 3.4 4.9e-05 22.3 2.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EME31814.1 - 0.00037 19.6 12.4 0.00045 19.3 8.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein MFS_1 PF07690.11 EME31816.1 - 1.6e-18 66.5 26.5 5.7e-12 45.0 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME31816.1 - 6e-09 34.8 2.7 6e-09 34.8 1.9 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EME31816.1 - 1.3e-08 33.9 4.2 2.6e-06 26.4 0.2 2.2 2 0 0 2 2 2 2 PUCC protein Sugar_tr PF00083.19 EME31816.1 - 1.7e-07 30.1 4.2 1.7e-07 30.1 2.9 3.6 2 2 0 2 2 2 1 Sugar (and other) transporter RRM_1 PF00076.17 EME31817.1 - 2.1e-34 116.9 0.1 6.7e-16 57.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31817.1 - 1.3e-30 105.1 0.0 1e-14 54.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31817.1 - 1.9e-15 56.4 0.4 6.6e-07 29.0 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EME31817.1 - 0.25 10.8 3.1 0.78 9.2 0.0 2.8 2 1 0 2 2 2 0 Ribonuclease B OB domain Glyco_transf_22 PF03901.12 EME31818.1 - 9.6e-86 288.3 39.5 1.1e-85 288.1 27.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AAR2 PF05282.6 EME31819.1 - 1.1e-37 129.8 4.7 1.5e-37 129.4 2.1 2.0 2 1 0 2 2 2 1 AAR2 protein FAM86 PF14904.1 EME31819.1 - 0.09 12.5 0.1 2.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Family of unknown function ChuX_HutX PF06228.8 EME31820.1 - 8.5e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX Hydrolase_6 PF13344.1 EME31820.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glycos_transf_2 PF00535.21 EME31821.1 - 7.1e-20 71.3 0.0 9.4e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME31821.1 - 6.1e-11 42.5 0.0 5.6e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EME31821.1 - 1.9e-05 23.9 1.4 0.04 12.9 0.3 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 WD40 PF00400.27 EME31822.1 - 1.2e-65 215.1 29.6 2.8e-12 45.9 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME31822.1 - 1.8e-12 47.3 0.3 3.1e-05 23.7 0.0 3.6 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME31822.1 - 1.4e-05 23.4 10.6 0.76 7.8 0.4 5.1 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME31822.1 - 1.9e-05 23.6 6.9 0.27 9.9 0.0 4.2 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EME31822.1 - 2.9e-05 22.5 4.8 0.098 10.9 0.0 3.7 2 1 2 4 4 4 3 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EME31822.1 - 3.1e-05 22.9 1.3 0.0012 17.6 0.0 2.9 1 1 1 3 3 3 1 Coatomer WD associated region Hira PF07569.6 EME31822.1 - 0.015 14.5 2.5 7.1 5.7 0.0 4.2 1 1 4 5 5 5 0 TUP1-like enhancer of split PQQ_3 PF13570.1 EME31822.1 - 0.55 10.5 5.5 7.1 7.0 0.0 3.9 3 2 0 3 3 3 0 PQQ-like domain Mito_carr PF00153.22 EME31823.1 - 1.1e-75 249.4 1.2 4.6e-27 93.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Adaptin_N PF01602.15 EME31824.1 - 5.7e-28 97.5 9.1 1.3e-27 96.3 6.3 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EME31824.1 - 0.025 14.8 0.1 18 5.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats Vwaint PF14624.1 EME31824.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 VWA / Hh protein intein-like Adaptin_N PF01602.15 EME31825.1 - 2.3e-28 98.8 9.4 5e-28 97.7 6.5 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EME31825.1 - 0.01 16.1 0.1 16 5.8 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats Vwaint PF14624.1 EME31825.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 VWA / Hh protein intein-like Proteasome PF00227.21 EME31826.1 - 4.9e-23 81.3 0.2 2e-22 79.4 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit GHMP_kinases_N PF00288.21 EME31826.1 - 0.011 15.7 0.3 0.027 14.5 0.1 1.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain Proteasome PF00227.21 EME31827.1 - 4.9e-23 81.3 0.2 2e-22 79.4 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit GHMP_kinases_N PF00288.21 EME31827.1 - 0.011 15.7 0.3 0.027 14.5 0.1 1.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain Fer2 PF00111.22 EME31828.1 - 3.3e-07 29.9 0.2 4.9e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 EME31828.1 - 0.1 12.4 0.1 0.26 11.0 0.1 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain BOP1NT PF08145.7 EME31829.1 - 8.2e-61 205.9 2.4 1.2e-60 205.5 1.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EME31829.1 - 1.2e-19 69.3 14.8 2.1e-06 27.3 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME31829.1 - 0.028 13.9 0.0 0.77 9.3 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EME31829.1 - 0.058 12.1 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region DUF3312 PF11768.3 EME31829.1 - 0.092 10.9 0.1 0.53 8.4 0.0 1.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3312) Hira PF07569.6 EME31829.1 - 0.1 11.7 0.1 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Acyltransferase PF01553.16 EME31830.1 - 3.2e-15 55.7 0.0 6.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase TPR_MLP1_2 PF07926.7 EME31831.1 - 3.4 7.4 8.9 0.44 10.2 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TRAP-gamma PF07074.7 EME31832.1 - 2.1e-10 40.3 11.1 3.4e-09 36.4 7.7 2.0 1 1 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF1049 PF06305.6 EME31832.1 - 0.057 12.8 0.7 0.057 12.8 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) MnhB PF04039.8 EME31832.1 - 2 8.4 10.2 0.074 13.1 1.8 2.1 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter zf-LITAF-like PF10601.4 EME31833.1 - 2.1e-06 27.4 13.1 3.4e-06 26.8 9.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.1 EME31833.1 - 0.011 14.9 1.8 0.011 14.9 1.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.6 EME31833.1 - 0.026 13.8 1.8 4.7 6.6 0.1 2.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) HypA PF01155.14 EME31833.1 - 0.038 13.6 0.4 0.038 13.6 0.3 1.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ADK_lid PF05191.9 EME31833.1 - 0.064 12.9 0.0 0.064 12.9 0.0 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid Ribosomal_L32p PF01783.18 EME31833.1 - 0.17 12.0 0.3 0.17 12.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L32p protein family DUF2735 PF10931.3 EME31833.1 - 0.2 11.9 2.3 0.31 11.3 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2735) zf-C4H2 PF10146.4 EME31833.1 - 9.6 6.1 7.2 16 5.4 5.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF663 PF04950.7 EME31836.1 - 9.5e-80 267.7 5.6 1e-79 267.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EME31836.1 - 5e-25 86.8 0.0 1.8e-24 85.0 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EME31836.1 - 2.5e-08 33.5 3.1 4.5e-07 29.4 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EME31836.1 - 8.2e-07 29.1 0.0 2.5e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME31836.1 - 0.0017 17.5 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EME31836.1 - 0.0017 17.8 0.1 0.0045 16.4 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EME31836.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EME31836.1 - 0.0028 18.1 1.5 0.0051 17.2 0.1 2.2 2 0 0 2 2 1 1 Miro-like protein ABC_tran PF00005.22 EME31836.1 - 0.0028 17.9 0.1 0.0028 17.9 0.0 3.0 4 0 0 4 4 3 1 ABC transporter MMR_HSR1 PF01926.18 EME31836.1 - 0.0054 16.6 0.2 0.024 14.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EME31836.1 - 0.006 16.2 1.2 0.014 15.0 0.8 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EME31836.1 - 0.016 15.0 0.2 0.016 15.0 0.2 2.6 3 1 0 3 3 2 0 AAA domain Guanylate_kin PF00625.16 EME31836.1 - 0.017 14.5 0.2 0.017 14.5 0.1 2.5 3 0 0 3 3 2 0 Guanylate kinase AAA_17 PF13207.1 EME31836.1 - 0.13 13.0 0.2 0.13 13.0 0.1 3.6 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EME31836.1 - 0.25 11.1 0.4 0.57 9.9 0.3 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EME31836.1 - 2.2 8.1 7.5 0.52 10.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain Translin PF01997.11 EME31838.1 - 9.4e-36 123.2 0.1 1.1e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Translin family COG5 PF10392.4 EME31838.1 - 0.00097 19.1 0.2 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 NPR3 PF03666.8 EME31838.1 - 0.074 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPF0184 PF03670.8 EME31838.1 - 0.11 12.6 0.6 0.27 11.4 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Lipoprotein_7 PF01540.11 EME31838.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein FMN_dh PF01070.13 EME31839.1 - 6.7e-135 449.5 0.0 7.8e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME31839.1 - 0.00038 19.4 0.2 0.0012 17.7 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EME31839.1 - 0.0023 17.0 0.4 0.0077 15.3 0.1 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EME31839.1 - 0.0027 16.6 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EME31839.1 - 0.0078 15.5 0.1 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EME31839.1 - 0.014 14.5 0.4 0.028 13.5 0.3 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase PA PF02225.17 EME31839.1 - 0.049 13.3 1.0 5.6 6.7 0.1 3.0 2 1 1 3 3 3 0 PA domain zf-C3HC4_3 PF13920.1 EME31840.1 - 6.1e-10 38.6 10.7 6.1e-10 38.6 7.4 2.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31840.1 - 0.017 15.1 14.4 0.017 15.1 10.0 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4200 PF13863.1 EME31841.1 - 0.0089 15.9 7.9 0.015 15.2 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DUF4484 PF14831.1 EME31841.1 - 0.014 15.5 0.5 0.019 15.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) ORF6C PF10552.4 EME31841.1 - 0.037 13.7 4.4 0.37 10.5 0.1 2.2 1 1 1 2 2 2 0 ORF6C domain DUF342 PF03961.8 EME31841.1 - 0.076 11.4 1.8 0.09 11.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C3HC4_3 PF13920.1 EME31841.1 - 0.15 11.7 8.4 0.94 9.2 5.8 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_23 PF13476.1 EME31841.1 - 0.23 11.7 4.5 0.31 11.3 3.1 1.1 1 0 0 1 1 1 0 AAA domain zf-RING_5 PF14634.1 EME31841.1 - 0.78 9.5 15.4 0.23 11.2 7.6 2.3 2 1 0 2 2 2 0 zinc-RING finger domain Fzo_mitofusin PF04799.8 EME31841.1 - 1 8.7 4.9 1.4 8.2 3.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region zf-C3HC4_2 PF13923.1 EME31841.1 - 1.2 9.2 12.1 0.62 10.1 5.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-FCS PF06467.9 EME31841.1 - 1.2 8.8 12.0 6.4 6.5 0.9 3.1 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif AAA_13 PF13166.1 EME31841.1 - 6.6 5.0 11.8 18 3.6 8.2 1.7 1 1 0 1 1 1 0 AAA domain DivIC PF04977.10 EME31841.1 - 8.4 5.9 13.4 0.17 11.4 2.3 2.3 1 1 1 2 2 2 0 Septum formation initiator ATP-synt_C PF00137.16 EME31843.1 - 0.088 12.7 0.3 0.088 12.7 0.2 2.0 2 0 0 2 2 2 0 ATP synthase subunit C Ribosomal_L1 PF00687.16 EME31844.1 - 1.4e-27 96.5 0.1 3e-27 95.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Rad17 PF03215.10 EME31845.1 - 5.5e-06 25.3 0.0 0.011 14.4 0.0 3.0 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EME31845.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME31845.1 - 0.0096 16.0 0.0 0.033 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME31845.1 - 0.019 14.3 0.0 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 EME31845.1 - 0.088 11.8 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME31845.1 - 0.1 12.1 0.2 0.41 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain PAPS_reduct PF01507.14 EME31846.1 - 1.8e-39 135.3 0.0 2.7e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.19 EME31846.1 - 3.8e-17 62.0 0.1 1.1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EME31846.1 - 0.00044 20.4 0.0 0.0036 17.5 0.0 2.5 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EME31846.1 - 0.0036 17.5 0.0 0.0077 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.1 EME31846.1 - 0.0077 15.7 0.0 0.047 13.1 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 EME31846.1 - 0.055 13.6 0.1 0.22 11.7 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Y_phosphatase PF00102.22 EME31847.1 - 6.9e-53 179.3 0.1 8.2e-53 179.1 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EME31847.1 - 0.00036 20.8 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EME31847.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EME31847.1 - 0.0021 18.0 0.1 0.0075 16.3 0.0 1.8 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EME31848.1 - 5e-57 192.9 0.2 9.6e-57 192.0 0.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Mito_carr PF00153.22 EME31848.1 - 1.1e-31 108.3 5.0 3.5e-13 49.0 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein Y_phosphatase3 PF13350.1 EME31848.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EME31848.1 - 0.0031 17.0 0.0 0.0073 15.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EME31848.1 - 0.0097 15.9 0.0 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate AAA_12 PF13087.1 EME31849.1 - 7.8e-60 201.6 0.3 2.3e-59 200.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EME31849.1 - 2.3e-58 197.5 0.0 4.4e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME31849.1 - 5.4e-10 39.1 0.0 4.6e-07 29.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EME31849.1 - 1.9e-09 37.1 0.0 8.1e-07 28.7 0.0 3.1 2 1 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EME31849.1 - 0.0021 17.6 1.5 0.24 10.8 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EME31849.1 - 0.005 16.9 0.0 0.22 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EME31849.1 - 0.0097 16.1 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EME31849.1 - 0.047 13.2 0.5 3.7 7.1 0.0 2.6 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EME31849.1 - 0.18 11.1 0.1 0.7 9.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Enkurin PF13864.1 EME31849.1 - 0.41 10.8 4.4 0.19 11.9 1.0 2.0 2 0 0 2 2 2 0 Calmodulin-binding DUF1365 PF07103.6 EME31850.1 - 2e-51 174.4 1.6 2.3e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF1365 PF07103.6 EME31851.1 - 2e-51 174.4 1.6 2.3e-51 174.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.15 EME31852.1 - 6.9e-56 189.3 0.1 1.4e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NAD_binding_8 PF13450.1 EME31852.1 - 1.2e-16 60.4 0.0 3.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME31852.1 - 5.5e-14 52.0 0.0 2.1e-13 50.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Methyltransf_18 PF12847.2 EME31852.1 - 1.2e-12 48.4 0.0 8e-11 42.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31852.1 - 4.8e-12 45.8 0.0 1.6e-11 44.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31852.1 - 5.9e-12 45.9 0.0 1.9e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.19 EME31852.1 - 1.4e-09 37.3 0.1 1.4e-07 30.7 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Methyltransf_12 PF08242.7 EME31852.1 - 4.1e-09 36.7 0.0 1.1e-07 32.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME31852.1 - 4.5e-08 32.8 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.1 EME31852.1 - 3e-06 27.1 0.7 0.064 13.0 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EME31852.1 - 3e-06 26.3 0.5 5.1e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME31852.1 - 4.4e-06 25.4 0.1 0.00042 18.9 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EME31852.1 - 1.9e-05 24.6 0.0 0.0004 20.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME31852.1 - 3e-05 24.3 0.7 0.00094 19.5 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME31852.1 - 9.9e-05 22.4 0.0 0.00072 19.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31852.1 - 0.00012 21.3 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EME31852.1 - 0.00012 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Methyltransf_26 PF13659.1 EME31852.1 - 0.00042 20.3 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FMO-like PF00743.14 EME31852.1 - 0.00065 18.0 0.0 0.0011 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Methyltransf_25 PF13649.1 EME31852.1 - 0.00069 19.9 0.1 0.0098 16.2 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.9 EME31852.1 - 0.0013 18.1 0.0 0.0038 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain UDPG_MGDP_dh_N PF03721.9 EME31852.1 - 0.0023 17.3 0.1 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_16 PF10294.4 EME31852.1 - 0.0046 16.4 0.5 0.04 13.3 0.0 2.6 2 1 1 3 3 3 1 Putative methyltransferase GIDA PF01134.17 EME31852.1 - 0.0053 15.6 0.2 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EME31852.1 - 0.0062 16.2 0.3 0.24 11.0 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RrnaAD PF00398.15 EME31852.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.21 EME31852.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Met_10 PF02475.11 EME31852.1 - 0.009 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 EME31852.1 - 0.011 14.9 0.3 0.12 11.4 0.2 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 EME31852.1 - 0.011 15.0 0.5 0.022 14.0 0.0 1.6 2 0 0 2 2 1 0 Histone methylation protein DOT1 NAD_Gly3P_dh_N PF01210.18 EME31852.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_3 PF01596.12 EME31852.1 - 0.039 13.0 0.1 0.092 11.7 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EME31852.1 - 0.044 12.8 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EME31852.1 - 0.056 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EME31852.1 - 0.056 12.9 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) ApbA PF02558.11 EME31852.1 - 0.056 12.8 2.4 0.1 12.0 0.3 2.3 3 0 0 3 3 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EME31852.1 - 0.058 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EME31852.1 - 0.14 11.6 0.1 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.15 EME31853.1 - 1.7e-45 155.2 0.2 2.4e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EME31853.1 - 1.2e-17 63.9 0.0 3.7e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31853.1 - 1.4e-14 54.0 0.0 2.3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31853.1 - 2.4e-13 50.4 0.0 9e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME31853.1 - 2.8e-12 47.2 0.0 4.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME31853.1 - 8.3e-10 39.0 0.0 1.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME31853.1 - 2.7e-08 33.1 0.0 1.9e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EME31853.1 - 4.2e-08 32.7 0.0 7.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EME31853.1 - 1.7e-06 28.3 0.0 3.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EME31853.1 - 2.2e-05 23.9 0.1 0.00036 19.9 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) GidB PF02527.10 EME31853.1 - 0.00014 21.0 0.0 0.00035 19.7 0.0 1.7 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EME31853.1 - 0.00016 21.7 0.0 0.00044 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EME31853.1 - 0.00033 19.8 0.0 0.00059 19.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 EME31853.1 - 0.00057 19.9 0.0 0.0011 18.9 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.6 EME31853.1 - 0.002 16.8 0.0 0.0034 16.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.4 EME31853.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EME31853.1 - 0.0048 16.4 0.1 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) PCMT PF01135.14 EME31853.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EME31853.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.13 EME31853.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase HAD PF12710.2 EME31854.1 - 2.6e-07 30.9 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 EME31854.1 - 1.8e-06 27.5 0.0 5.1e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.7 EME31854.1 - 0.0005 19.7 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME31854.1 - 0.0026 18.0 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ACT PF01842.20 EME31854.1 - 0.078 12.4 0.0 0.43 10.1 0.0 2.3 1 0 0 1 1 1 0 ACT domain Hydrolase PF00702.21 EME31854.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 EME31856.1 - 2.6e-27 95.7 4.6 3.3e-27 95.4 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME31856.1 - 1.7e-20 73.7 0.1 2.1e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME31856.1 - 2.6e-10 40.2 2.9 4.1e-10 39.6 2.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME31856.1 - 0.00018 21.1 0.3 0.00045 19.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EME31856.1 - 0.00054 18.9 0.0 0.00079 18.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3186 PF11382.3 EME31856.1 - 0.0098 15.0 0.2 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) THF_DHG_CYH_C PF02882.14 EME31856.1 - 0.015 14.3 0.2 0.05 12.6 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EME31856.1 - 0.031 14.0 0.7 0.079 12.7 0.5 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EME31856.1 - 0.034 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_C78 PF07910.8 EME31857.1 - 1.5e-35 122.3 4.0 3.4e-35 121.1 2.8 1.5 1 0 0 1 1 1 1 Peptidase family C78 AAA PF00004.24 EME31858.1 - 5.9e-17 62.1 0.1 5.9e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EME31858.1 - 3.9e-15 55.6 0.1 1.7e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EME31858.1 - 1.8e-13 50.4 0.1 2e-09 37.2 0.0 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.10 EME31858.1 - 8.1e-09 34.6 0.0 0.00022 20.0 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EME31858.1 - 4.1e-06 26.9 1.1 0.097 12.8 0.0 3.0 2 1 1 3 3 3 2 AAA domain DNA_pol3_delta PF06144.8 EME31858.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EME31858.1 - 3e-05 23.7 0.0 5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME31858.1 - 3.4e-05 23.0 0.0 6.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EME31858.1 - 3.8e-05 23.7 0.0 0.0018 18.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EME31858.1 - 8.9e-05 22.1 0.1 0.00026 20.6 0.0 1.9 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EME31858.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EME31858.1 - 0.00061 19.3 0.1 0.014 14.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.8 EME31858.1 - 0.00093 18.1 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EME31858.1 - 0.0015 18.0 0.6 0.027 13.9 0.4 2.6 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EME31858.1 - 0.0017 18.0 0.0 0.0067 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME31858.1 - 0.0024 17.2 0.5 0.041 13.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_3 PF07726.6 EME31858.1 - 0.0026 17.3 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EME31858.1 - 0.011 15.2 0.4 0.022 14.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EME31858.1 - 0.013 14.7 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.18 EME31858.1 - 0.016 13.9 0.2 0.14 10.9 0.0 2.4 2 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_30 PF13604.1 EME31858.1 - 0.019 14.5 0.2 0.41 10.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain BRCT_assoc PF12820.2 EME31858.1 - 0.029 14.1 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT AAA_18 PF13238.1 EME31858.1 - 0.073 13.3 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME31858.1 - 0.08 13.7 0.2 0.33 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME31858.1 - 0.086 12.2 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 EME31858.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PWI PF01480.12 EME31859.1 - 5.7e-24 84.0 1.1 7.7e-24 83.6 0.1 1.8 2 0 0 2 2 2 1 PWI domain Myb_DNA-binding PF00249.26 EME31860.1 - 1.8e-10 40.7 0.1 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pox_A_type_inc PF04508.7 EME31860.1 - 0.033 13.9 3.2 0.07 12.9 1.5 2.3 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat Glyco_hydro_35 PF01301.14 EME31861.1 - 6.7e-88 295.0 0.7 1.1e-87 294.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EME31861.1 - 3e-42 143.3 1.2 1.4e-21 76.8 0.0 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EME31861.1 - 4.6e-27 94.5 0.0 7.5e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EME31861.1 - 1.2e-13 50.1 0.0 3.4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 EME31861.1 - 7.1e-10 38.6 0.2 4.6e-07 29.5 0.2 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_42 PF02449.10 EME31861.1 - 4.8e-08 32.5 0.0 1.2e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 Beta-galactosidase RasGAP_C PF03836.10 EME31862.1 - 0.027 14.1 0.0 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 RasGAP C-terminus PI3K_p85B PF02192.11 EME31862.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain ADH_zinc_N_2 PF13602.1 EME31863.1 - 5.1e-18 66.1 0.0 8.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EME31863.1 - 1.3e-12 47.4 0.0 4.1e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME31863.1 - 2.4e-11 43.3 0.0 1.1e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EME31863.1 - 0.00034 20.2 0.1 0.00064 19.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.3 EME31863.1 - 0.078 12.7 0.8 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.7 EME31864.1 - 1e-11 44.5 0.0 3.4e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME31864.1 - 1.8e-08 33.9 0.1 3.7e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME31864.1 - 0.0002 20.9 0.1 0.00037 20.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.3 EME31864.1 - 0.049 13.4 0.8 0.096 12.4 0.6 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GalKase_gal_bdg PF10509.4 EME31865.1 - 8.9e-23 79.3 0.1 6e-22 76.6 0.0 2.2 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EME31865.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EME31865.1 - 2.6e-08 33.7 0.1 6.5e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain HHH_8 PF14716.1 EME31865.1 - 0.1 12.7 0.2 6.2 7.0 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain FANCF PF11107.3 EME31866.1 - 0.0032 16.7 3.7 0.43 9.7 2.6 2.5 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Asp PF00026.18 EME31867.1 - 4.5e-46 157.5 0.0 6.3e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME31867.1 - 3.9e-12 45.9 0.0 7.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EME31867.1 - 1.1e-05 25.4 5.2 2.1e-05 24.5 3.6 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.18 EME31868.1 - 1.9e-43 148.9 10.3 1.2e-42 146.3 7.1 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME31868.1 - 2e-12 46.9 0.2 1.6e-11 43.9 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EME31868.1 - 0.0014 19.0 0.6 0.082 13.4 0.1 2.8 2 0 0 2 2 2 1 Aspartyl protease Cyt-b5 PF00173.23 EME31869.1 - 1.1e-09 37.9 0.0 1.7e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4131 PF13567.1 EME31869.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Aminotran_4 PF01063.14 EME31870.1 - 2.8e-19 69.4 0.0 4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV NIF PF03031.13 EME31871.1 - 2.1e-47 160.7 0.0 2.9e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EME31871.1 - 0.0096 16.1 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase VD10_N PF08476.5 EME31871.1 - 0.12 11.8 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral D10 N-terminal tRNA-synt_1d PF00750.14 EME31872.1 - 3.5e-104 348.4 0.2 4.5e-104 348.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EME31872.1 - 2e-29 101.9 2.2 9.4e-29 99.7 0.1 2.7 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EME31872.1 - 2.6e-22 79.1 0.0 1.7e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.6 EME31872.1 - 0.00071 18.3 0.0 0.0013 17.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EME31872.1 - 0.009 15.1 0.0 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 EME31872.1 - 0.072 11.0 0.1 0.15 10.0 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) Histone PF00125.19 EME31873.1 - 3.9e-14 52.5 0.2 5.3e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME31873.1 - 0.0012 18.9 0.5 0.0018 18.3 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EME31873.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TAF PF02969.12 EME31873.1 - 0.09 12.7 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) FMN_red PF03358.10 EME31874.1 - 1.3e-12 47.4 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EME31874.1 - 7e-10 38.7 0.0 8.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EME31874.1 - 6e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 EME31874.1 - 0.00065 19.0 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin SAP30_Sin3_bdg PF13867.1 EME31875.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.27 EME31876.1 - 4.1e-22 77.1 6.2 3.9e-09 36.0 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Cyclin_N PF00134.18 EME31877.1 - 1.4e-21 76.3 2.1 1.4e-21 76.3 1.5 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME31877.1 - 2.1e-06 27.6 0.5 6.5e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain CPSase_L_D2 PF02786.12 EME31878.1 - 5.5e-81 270.8 0.1 9.5e-81 270.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME31878.1 - 1.7e-42 143.9 0.2 5.9e-42 142.2 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME31878.1 - 4.7e-37 126.2 0.0 1e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EME31878.1 - 3e-19 69.4 0.0 7e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME31878.1 - 2.6e-12 46.1 0.0 2.9e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME31878.1 - 5.8e-11 42.0 0.1 3.2e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME31878.1 - 1.4e-08 34.3 0.0 4.3e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EME31878.1 - 5.9e-08 32.4 0.0 1.3e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EME31878.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Oxidored_nitro PF00148.14 EME31878.1 - 0.0089 14.7 0.1 0.055 12.1 0.0 2.1 1 1 1 3 3 3 1 Nitrogenase component 1 type Oxidoreductase ATP-grasp_5 PF13549.1 EME31878.1 - 0.0097 15.1 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EME31878.1 - 0.084 12.2 0.3 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Peripla_BP_3 PF13377.1 EME31878.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain CPSase_L_D2 PF02786.12 EME31879.1 - 5.3e-81 270.9 0.1 9.3e-81 270.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME31879.1 - 6.4e-44 148.5 0.3 2.2e-43 146.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME31879.1 - 4.9e-37 126.1 0.0 1e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EME31879.1 - 3.1e-19 69.4 0.0 6.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME31879.1 - 1.1e-13 50.5 0.0 1.2e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME31879.1 - 5.6e-11 42.0 0.1 3.1e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME31879.1 - 1.4e-08 34.3 0.0 4.3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EME31879.1 - 5.8e-08 32.4 0.0 1.3e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EME31879.1 - 0.00013 21.9 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Oxidored_nitro PF00148.14 EME31879.1 - 0.0068 15.0 0.1 0.05 12.2 0.1 2.2 1 1 2 3 3 3 1 Nitrogenase component 1 type Oxidoreductase ATP-grasp_5 PF13549.1 EME31879.1 - 0.0095 15.1 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EME31879.1 - 0.082 12.2 0.3 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Peripla_BP_3 PF13377.1 EME31879.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain MMR_HSR1 PF01926.18 EME31880.1 - 6.7e-19 67.9 0.1 2.6e-18 66.0 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME31880.1 - 9.1e-07 28.2 0.1 2.6e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EME31880.1 - 3.4e-05 23.3 0.0 0.001 18.5 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EME31880.1 - 0.00019 20.6 0.1 0.00065 18.9 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EME31880.1 - 0.00059 19.7 0.5 0.3 10.9 0.5 2.7 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EME31880.1 - 0.0008 18.6 0.0 0.0017 17.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME31880.1 - 0.0044 17.3 0.1 0.21 11.9 0.0 2.7 2 1 0 2 2 2 1 ABC transporter MobB PF03205.9 EME31880.1 - 0.015 15.0 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EME31880.1 - 0.017 15.5 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein PTH2 PF01981.11 EME31880.1 - 0.032 13.9 0.1 0.063 12.9 0.1 1.6 1 1 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DUF1722 PF08349.6 EME31880.1 - 0.05 13.4 0.2 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) AAA_10 PF12846.2 EME31880.1 - 0.055 12.9 0.0 1.2 8.4 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EME31880.1 - 0.069 13.9 0.0 0.3 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME31880.1 - 0.17 12.1 1.4 0.93 9.8 0.0 2.8 2 2 0 2 2 2 0 AAA domain Thioredoxin PF00085.15 EME31881.1 - 0.00075 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME31881.1 - 0.039 14.0 0.1 0.091 12.8 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like LRR_4 PF12799.2 EME31882.1 - 7.8e-13 47.7 14.7 1.4e-07 30.9 3.6 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EME31882.1 - 1.8e-09 36.2 16.2 0.0026 17.5 0.3 4.9 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_8 PF13855.1 EME31882.1 - 2.3e-09 36.8 12.9 5.8e-06 25.9 1.7 3.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 EME31882.1 - 0.0009 19.0 12.1 0.25 11.6 0.2 4.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EME31882.1 - 0.043 13.9 10.9 4.5 7.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF2009 PF09418.5 EME31882.1 - 0.13 10.9 2.4 0.17 10.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) LRR_4 PF12799.2 EME31883.1 - 5.8e-16 57.7 23.4 1.1e-07 31.2 2.9 4.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME31883.1 - 7.9e-12 44.7 11.8 8.5e-08 31.8 1.3 3.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EME31883.1 - 8e-11 40.4 13.8 0.0027 17.4 0.3 5.0 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 EME31883.1 - 0.0012 18.6 12.2 0.27 11.5 0.2 4.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EME31883.1 - 0.04 13.9 10.6 4.7 7.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF2009 PF09418.5 EME31883.1 - 0.14 10.8 2.3 0.18 10.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) BATS PF06968.8 EME31884.1 - 3.2e-24 84.5 0.0 8.3e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EME31884.1 - 2e-18 67.1 0.0 2.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Metallophos_2 PF12850.2 EME31885.1 - 2.2e-12 47.0 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EME31885.1 - 5.9e-09 35.6 1.4 3.6e-08 33.0 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GARS_N PF02844.10 EME31885.1 - 0.095 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Pkinase PF00069.20 EME31886.1 - 2.8e-65 220.0 0.0 3.8e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31886.1 - 4e-36 124.4 0.0 5.9e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31886.1 - 0.013 14.4 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EME31886.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME31886.1 - 0.19 11.4 0.1 0.72 9.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ParA PF10609.4 EME31887.1 - 3.1e-35 119.8 0.0 5.7e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EME31887.1 - 1.2e-20 73.7 0.0 1.6e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EME31887.1 - 2.9e-08 33.1 0.0 8e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EME31887.1 - 9.9e-08 32.0 0.0 4.5e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EME31887.1 - 2.3e-05 23.7 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EME31887.1 - 0.00042 19.4 2.9 0.0018 17.4 0.7 2.6 3 1 0 4 4 4 1 Anion-transporting ATPase AAA_26 PF13500.1 EME31887.1 - 0.0064 16.1 0.6 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain YhjQ PF06564.7 EME31887.1 - 0.011 15.0 0.7 0.043 13.1 0.5 1.9 1 1 0 1 1 1 0 YhjQ protein VirC1 PF07015.6 EME31887.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein APS_kinase PF01583.15 EME31887.1 - 0.13 11.9 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RINGv PF12906.2 EME31888.1 - 3e-15 55.9 8.4 3e-15 55.9 5.8 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EME31888.1 - 0.73 9.7 12.9 0.12 12.2 5.7 2.1 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.1 EME31888.1 - 1.7 8.7 12.6 0.38 10.8 5.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31888.1 - 2.2 7.9 12.6 0.9 9.2 5.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-AD PF07776.10 EME31888.1 - 3.3 7.7 11.5 0.44 10.5 5.0 1.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-RING-like PF08746.6 EME31888.1 - 3.6 7.6 11.1 0.33 10.9 4.0 2.1 2 1 0 2 2 2 0 RING-like domain DNase-RNase PF02577.9 EME31889.1 - 2.5e-27 94.7 0.0 4e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.14 EME31889.1 - 0.0096 15.4 1.4 0.0096 15.4 1.0 2.8 4 0 0 4 4 4 1 UvrB/uvrC motif Pkinase PF00069.20 EME31890.1 - 3.8e-59 199.9 0.9 1.3e-58 198.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31890.1 - 1.3e-31 109.5 0.0 2.6e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31890.1 - 0.0024 17.6 0.2 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME31890.1 - 0.0051 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME31890.1 - 0.015 14.6 0.1 0.05 12.9 0.1 1.9 1 1 0 1 1 1 0 RIO1 family FUSC_2 PF13515.1 EME31891.1 - 6.1e-08 32.6 16.0 6.1e-08 32.6 11.1 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like 4HBT_2 PF13279.1 EME31891.1 - 0.14 12.6 0.8 16 5.9 0.1 3.5 2 1 0 3 3 3 0 Thioesterase-like superfamily Pkinase PF00069.20 EME31892.1 - 1.2e-61 208.1 0.0 1.5e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31892.1 - 1.7e-35 122.3 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31892.1 - 3e-07 29.6 0.0 4.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME31892.1 - 0.00058 19.6 0.0 0.061 13.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME31892.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EME31892.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Img2 PF05046.9 EME31893.1 - 7.4e-10 38.9 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EME31893.1 - 0.00083 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 CBFB_NFYA PF02045.10 EME31894.1 - 7.8e-22 77.5 11.6 1.2e-21 76.9 8.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LMBR1 PF04791.11 EME31894.1 - 0.071 11.6 0.5 0.082 11.4 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.27 EME31895.1 - 4.1e-08 32.7 2.7 0.00075 19.2 0.6 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Galactosyl_T PF01762.16 EME31896.1 - 0.00078 19.0 1.3 0.0035 16.9 0.9 2.1 1 1 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.16 EME31897.1 - 0.0008 19.0 1.3 0.0035 16.9 0.9 2.1 1 1 0 1 1 1 1 Galactosyltransferase Pantoate_ligase PF02569.10 EME31898.1 - 1.7e-65 220.6 0.1 3e-43 147.5 0.0 2.0 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase Pantoate_ligase PF02569.10 EME31899.1 - 6.5e-81 271.1 0.0 9.7e-59 198.4 0.0 2.0 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase ABC_membrane PF00664.18 EME31900.1 - 4.7e-12 45.8 7.7 3.1e-09 36.6 0.8 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME31900.1 - 0.0011 19.2 0.0 0.005 17.1 0.0 2.2 1 1 0 1 1 1 1 ABC transporter Glyoxalase PF00903.20 EME31901.1 - 3.3e-29 101.4 0.1 2.6e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME31901.1 - 3.2e-25 88.8 0.0 2.1e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EME31901.1 - 4.9e-12 45.8 0.0 4.1e-06 26.7 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EME31901.1 - 0.00062 19.4 0.1 0.54 9.9 0.0 2.7 3 0 0 3 3 3 2 CppA N-terminal Peptidase_S24 PF00717.18 EME31902.1 - 4.4e-13 48.6 0.1 8.5e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EME31902.1 - 4.7e-13 48.8 0.0 7.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF900 PF05990.7 EME31903.1 - 8e-20 71.1 0.0 4e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 EME31903.1 - 0.0039 17.0 0.3 0.0069 16.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mito_fiss_reg PF05308.6 EME31903.1 - 0.14 11.5 1.4 0.24 10.7 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C3HC4_2 PF13923.1 EME31904.1 - 2.5e-07 30.5 11.9 5.9e-07 29.4 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME31904.1 - 1.3e-06 28.1 11.1 3.2e-06 26.9 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EME31904.1 - 2.6e-06 26.9 9.7 2.6e-06 26.9 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME31904.1 - 2.6e-05 23.8 12.0 5.8e-05 22.6 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME31904.1 - 7.4e-05 22.4 14.7 7.4e-05 22.4 10.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME31904.1 - 0.00047 19.8 13.9 0.0011 18.6 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME31904.1 - 0.0048 16.5 7.9 0.016 14.9 5.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DUF4297 PF14130.1 EME31905.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) Proteasom_PSMB PF10508.4 EME31906.1 - 7.9e-29 100.2 11.3 1e-28 99.8 7.8 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 EME31906.1 - 3e-05 24.2 3.3 0.049 13.9 0.2 4.3 2 1 1 3 3 3 3 HEAT repeats TIP120 PF08623.5 EME31906.1 - 0.0011 18.5 0.4 0.59 9.7 0.0 2.4 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) RICTOR_V PF14668.1 EME31906.1 - 0.0025 17.7 1.4 0.2 11.6 0.0 3.9 3 2 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 EME31906.1 - 0.019 15.0 0.8 17 5.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat DUF2435 PF10363.4 EME31906.1 - 0.077 12.9 0.5 3.8 7.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EME31906.1 - 2.1 8.9 4.5 29 5.3 0.1 3.7 4 0 0 4 4 4 0 HEAT-like repeat C2 PF00168.25 EME31907.1 - 5.5e-20 71.0 0.0 2e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EME31907.1 - 2.8e-08 33.7 0.0 8.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) HAD_2 PF13419.1 EME31908.1 - 1.4e-22 80.7 0.0 1.9e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME31908.1 - 1.1e-09 37.8 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME31908.1 - 3.1e-09 37.5 0.0 2.9e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EME31908.1 - 0.14 11.8 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase DUF1992 PF09350.5 EME31909.1 - 1.3e-15 56.9 0.2 3.2e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Amino_oxidase PF01593.19 EME31910.1 - 1.2e-34 120.1 0.0 1.5e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME31910.1 - 1.9e-11 43.8 0.0 3.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME31910.1 - 6.1e-08 31.9 0.0 9.3e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME31910.1 - 3.2e-06 26.2 0.1 4.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME31910.1 - 2.7e-05 23.4 0.2 4.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EME31910.1 - 0.00015 21.0 0.1 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME31910.1 - 0.0011 18.8 0.2 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31910.1 - 0.0018 17.4 0.1 0.0034 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EME31910.1 - 0.0046 15.4 0.3 0.0074 14.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EME31910.1 - 0.0071 15.2 0.4 0.011 14.5 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME31910.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EME31910.1 - 0.015 14.9 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EME31910.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EME31910.1 - 0.05 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 EME31910.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EME31910.1 - 0.14 11.9 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME31910.1 - 0.15 12.4 1.1 0.46 10.9 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PPR_2 PF13041.1 EME31912.1 - 1.1e-31 108.5 0.5 2.1e-13 50.0 0.0 5.6 4 2 2 6 6 6 5 PPR repeat family PPR_3 PF13812.1 EME31912.1 - 5.4e-23 79.2 0.0 0.0023 18.0 0.0 7.1 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME31912.1 - 9e-20 69.8 0.2 7.7e-05 22.0 0.0 5.8 5 0 0 5 5 5 4 PPR repeat PPR PF01535.15 EME31912.1 - 8.7e-18 63.0 9.5 9e-05 22.2 0.0 7.3 7 1 0 7 7 7 4 PPR repeat DUF433 PF04255.9 EME31912.1 - 0.05 13.0 0.1 3.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) PPR_2 PF13041.1 EME31913.1 - 3.8e-31 106.8 0.2 9.8e-13 47.8 0.0 5.6 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.1 EME31913.1 - 2.5e-20 70.9 0.1 0.0023 18.0 0.0 7.4 8 1 0 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME31913.1 - 7e-19 67.0 0.6 7.7e-05 22.0 0.0 5.8 5 0 0 5 5 5 4 PPR repeat PPR PF01535.15 EME31913.1 - 2.4e-17 61.6 9.8 9e-05 22.2 0.0 7.1 8 0 0 8 8 8 4 PPR repeat DUF433 PF04255.9 EME31913.1 - 0.052 12.9 0.1 3.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) ECSIT PF06239.6 EME31913.1 - 0.054 12.3 0.1 3.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF563 PF04577.9 EME31914.1 - 8e-20 71.6 2.7 1.7e-19 70.5 0.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF563) eIF3_subunit PF08597.5 EME31915.1 - 2.2e-29 102.7 25.6 2.6e-29 102.5 17.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Actin PF00022.14 EME31916.1 - 5.1e-117 390.6 0.0 5.9e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Actin PEX11 PF05648.9 EME31917.1 - 2.2e-35 121.9 4.1 2.8e-35 121.6 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M41 PF01434.13 EME31918.1 - 1e-76 257.1 0.0 1.9e-76 256.2 0.0 1.5 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.24 EME31918.1 - 4.3e-45 153.1 0.0 9.2e-45 152.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME31918.1 - 4.4e-06 26.4 0.4 4.4e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME31918.1 - 8.9e-05 23.2 0.4 0.00029 21.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EME31918.1 - 0.00017 20.4 0.1 0.00034 19.4 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EME31918.1 - 0.00021 21.4 0.0 0.035 14.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME31918.1 - 0.00044 19.9 1.7 0.0014 18.3 0.3 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EME31918.1 - 0.00093 19.2 0.3 0.023 14.6 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EME31918.1 - 0.0015 17.6 0.0 0.0063 15.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus FtsH_ext PF06480.10 EME31918.1 - 0.0016 18.5 0.0 0.0067 16.5 0.0 2.1 2 0 0 2 2 1 1 FtsH Extracellular AAA_14 PF13173.1 EME31918.1 - 0.003 17.4 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EME31918.1 - 0.0064 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME31918.1 - 0.0077 16.2 0.1 0.043 13.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 EME31918.1 - 0.0091 15.9 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EME31918.1 - 0.0098 15.3 0.1 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME31918.1 - 0.028 13.5 0.1 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EME31918.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EME31918.1 - 0.037 13.4 1.4 3.5 6.9 0.1 2.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EME31918.1 - 0.037 13.6 0.1 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EME31918.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EME31918.1 - 0.099 12.2 0.2 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EME31918.1 - 1.1 8.5 4.0 0.37 9.9 0.1 2.2 3 0 0 3 3 3 0 PhoH-like protein DUF445 PF04286.7 EME31921.1 - 0.081 12.4 2.2 0.096 12.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GIY-YIG PF01541.19 EME31922.1 - 8.9e-10 38.8 0.0 3e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 GIY-YIG catalytic domain T5orf172 PF10544.4 EME31922.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 T5orf172 domain HMGL-like PF00682.14 EME31923.1 - 1.3e-34 119.9 0.0 2e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EME31923.1 - 1.4e-19 70.1 0.0 2e-18 66.4 0.0 2.2 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF556 PF04476.8 EME31923.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF556) TLD PF07534.11 EME31924.1 - 1e-37 129.2 2.4 1.1e-37 129.1 0.5 1.9 2 0 0 2 2 2 1 TLD DivIC PF04977.10 EME31924.1 - 0.074 12.5 0.4 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Misat_Tub_SegII PF10644.4 EME31924.1 - 0.12 12.4 2.1 0.19 11.8 0.1 2.4 3 0 0 3 3 3 0 Misato Segment II tubulin-like domain FA_hydroxylase PF04116.8 EME31925.1 - 4.4e-11 43.2 21.5 4.4e-11 43.2 14.9 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily EF_assoc_1 PF08355.7 EME31925.1 - 0.078 12.2 1.1 0.19 11.0 0.8 1.6 1 0 0 1 1 1 0 EF hand associated EMP24_GP25L PF01105.19 EME31926.1 - 2e-36 125.4 0.0 2.4e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.1 EME31926.1 - 0.059 13.4 0.4 0.086 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) UCH PF00443.24 EME31927.1 - 1.8e-28 99.4 17.4 1.8e-28 99.4 12.0 3.2 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME31927.1 - 2.7e-09 36.8 4.9 2.7e-09 36.8 3.4 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF1838 PF08894.6 EME31928.1 - 8.5e-09 34.9 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) Spc97_Spc98 PF04130.8 EME31929.1 - 3.9e-65 220.2 15.9 3.9e-65 220.2 11.0 1.9 1 1 1 2 2 2 1 Spc97 / Spc98 family HycH PF07450.6 EME31929.1 - 0.028 14.5 0.1 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH MMR_HSR1 PF01926.18 EME31931.1 - 5.4e-50 168.2 0.1 8.3e-27 93.4 0.0 2.6 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EME31931.1 - 1.7e-33 114.4 0.3 4.1e-33 113.1 0.2 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.22 EME31931.1 - 2.3e-23 82.6 0.5 1.3e-11 44.2 0.3 4.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME31931.1 - 1.2e-22 79.8 0.0 7.5e-13 48.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 EME31931.1 - 7.5e-17 61.9 0.0 3.1e-07 30.9 0.0 3.0 2 1 1 3 3 3 2 Miro-like protein Dynamin_N PF00350.18 EME31931.1 - 1.1e-15 57.9 0.2 4.5e-05 23.3 0.0 5.1 4 2 1 5 5 5 3 Dynamin family AIG1 PF04548.11 EME31931.1 - 8.9e-13 47.8 0.0 2.4e-06 26.8 0.0 2.9 3 0 0 3 3 3 2 AIG1 family DUF258 PF03193.11 EME31931.1 - 4.5e-08 32.4 0.0 0.002 17.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME31931.1 - 5.7e-08 33.6 0.3 0.0072 17.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EME31931.1 - 3.2e-07 30.7 0.0 0.014 15.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 EME31931.1 - 3.2e-07 30.6 0.0 0.003 17.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain SRPRB PF09439.5 EME31931.1 - 5.7e-07 28.9 0.0 0.0011 18.2 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit cobW PF02492.14 EME31931.1 - 6.2e-07 29.0 2.7 0.0046 16.4 0.2 3.9 2 2 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 EME31931.1 - 6.9e-07 28.8 0.2 0.028 13.7 0.1 3.4 2 2 0 2 2 2 2 Ras family AAA_22 PF13401.1 EME31931.1 - 3.1e-06 27.3 0.0 0.0092 16.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain ArgK PF03308.11 EME31931.1 - 3.5e-06 26.0 1.5 0.19 10.5 0.0 4.7 5 0 0 5 5 5 1 ArgK protein Arch_ATPase PF01637.13 EME31931.1 - 8.3e-06 25.6 0.2 0.06 13.0 0.1 2.8 2 0 0 2 2 2 2 Archaeal ATPase Arf PF00025.16 EME31931.1 - 1.7e-05 24.1 1.7 0.089 12.0 0.2 3.7 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_25 PF13481.1 EME31931.1 - 3.6e-05 23.2 0.0 0.27 10.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EME31931.1 - 4.1e-05 23.1 0.0 0.2 11.0 0.0 3.4 3 1 1 4 4 3 1 FtsK/SpoIIIE family MobB PF03205.9 EME31931.1 - 0.00011 21.9 0.0 0.11 12.1 0.0 3.0 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B GBP PF02263.14 EME31931.1 - 0.00037 19.6 0.0 0.51 9.3 0.0 2.4 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_10 PF12846.2 EME31931.1 - 0.0007 19.1 0.0 0.63 9.4 0.0 3.0 2 2 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EME31931.1 - 0.00072 19.4 0.0 0.2 11.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME31931.1 - 0.0011 18.9 0.0 1.1 9.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 EME31931.1 - 0.0018 18.4 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.12 EME31931.1 - 0.002 17.6 0.0 3.3 7.1 0.1 3.6 3 1 1 4 4 4 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EME31931.1 - 0.0041 17.1 0.0 1.2 9.0 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EME31931.1 - 0.0047 16.0 0.0 3.7 6.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin KTI12 PF08433.5 EME31931.1 - 0.0075 15.5 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 EME31931.1 - 0.0085 15.9 0.0 0.78 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EME31931.1 - 0.014 15.5 0.0 8.2 6.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EME31931.1 - 0.02 14.6 0.1 1.2 8.7 0.0 2.9 2 2 0 2 2 2 0 NTPase AAA_29 PF13555.1 EME31931.1 - 0.026 14.0 0.0 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain TPP_enzyme_M PF00205.17 EME31931.1 - 0.091 12.5 0.8 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lambda_CIII PF02061.11 EME31931.1 - 0.1 12.5 0.6 4 7.5 0.0 3.1 3 0 0 3 3 3 0 Lambda Phage CIII YccJ PF13993.1 EME31931.1 - 0.13 12.3 0.2 0.64 10.1 0.1 2.2 2 0 0 2 2 1 0 YccJ-like protein Peptidase_M20 PF01546.23 EME31932.1 - 5.9e-29 100.9 0.0 7.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME31932.1 - 1.4e-23 82.7 0.0 2.2e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF525 PF04379.9 EME31933.1 - 7.2e-12 45.1 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Methyltransf_31 PF13847.1 EME31935.1 - 3.2e-16 59.2 0.0 4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME31935.1 - 3.3e-15 56.6 0.0 4.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME31935.1 - 3.1e-10 40.3 0.0 4.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME31935.1 - 3e-09 37.1 0.0 4.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME31935.1 - 7.4e-09 35.9 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME31935.1 - 2.8e-07 30.4 0.0 3.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME31935.1 - 2.5e-05 24.2 0.0 0.00016 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EME31935.1 - 7.2e-05 22.2 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 EME31935.1 - 0.00037 19.7 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EME31935.1 - 0.00041 19.7 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EME31935.1 - 0.00065 19.2 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 EME31935.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EME31935.1 - 0.0066 16.5 0.1 0.012 15.7 0.1 1.5 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Ubie_methyltran PF01209.13 EME31935.1 - 0.025 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EME31935.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EME31935.1 - 0.032 12.9 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 EME31935.1 - 0.039 13.0 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EME31935.1 - 0.039 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.15 EME31935.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Acetyltransf_1 PF00583.19 EME31936.1 - 1.8e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME31936.1 - 1.1e-08 35.1 0.9 1.5e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME31936.1 - 1.7e-05 24.7 0.0 2.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME31936.1 - 5e-05 23.3 0.0 6.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME31936.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EME31936.1 - 0.0028 17.8 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME31936.1 - 0.0051 16.6 0.0 0.0084 15.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME31936.1 - 0.014 15.2 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EME31936.1 - 0.024 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain USP8_dimer PF08969.6 EME31936.1 - 0.13 12.2 0.2 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 USP8 dimerisation domain TMEM18 PF14770.1 EME31937.1 - 8e-31 106.1 1.2 1e-30 105.7 0.8 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 Pyr_redox_2 PF07992.9 EME31938.1 - 6.6e-44 150.1 0.2 1e-43 149.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME31938.1 - 1.2e-32 112.2 0.2 3.1e-32 110.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EME31938.1 - 1.8e-19 69.9 9.1 2.9e-18 66.0 0.0 3.0 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME31938.1 - 1.3e-14 54.7 0.0 3.2e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME31938.1 - 1.9e-10 39.7 1.2 0.00039 19.0 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 EME31938.1 - 1.6e-06 27.5 0.0 8.1e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME31938.1 - 2.1e-06 27.0 0.7 2.1e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EME31938.1 - 0.00047 19.1 0.6 0.00047 19.1 0.5 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME31938.1 - 0.0015 17.4 8.9 0.0055 15.6 5.0 2.5 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EME31938.1 - 0.01 14.7 9.4 0.012 14.5 0.4 3.5 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EME31938.1 - 0.018 14.2 0.2 0.85 8.7 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EME31938.1 - 0.018 13.9 0.0 0.065 12.1 0.0 1.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.1 EME31938.1 - 0.022 15.0 0.4 21 5.4 0.0 3.3 3 0 0 3 3 3 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EME31938.1 - 0.04 13.4 2.4 3.8 7.0 0.2 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EME31938.1 - 0.054 13.5 1.1 0.19 11.7 0.7 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME31938.1 - 0.68 9.6 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EME31938.1 - 0.78 9.3 6.1 14 5.2 0.0 3.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME31938.1 - 4.6 6.1 6.7 0.44 9.5 1.1 1.8 2 0 0 2 2 2 0 FAD binding domain Baculo_PEP_C PF04513.7 EME31939.1 - 0.059 13.2 0.7 0.25 11.1 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4315 PF14193.1 EME31939.1 - 0.067 13.1 3.1 0.088 12.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF745 PF05335.8 EME31939.1 - 0.12 11.8 3.4 0.23 10.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ATP-synt_B PF00430.13 EME31939.1 - 0.78 9.5 7.7 2.4 7.9 0.5 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Pkinase PF00069.20 EME31940.1 - 2.1e-75 253.2 0.0 2.9e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31940.1 - 5.8e-44 150.1 0.0 7.8e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME31940.1 - 3e-07 30.4 0.3 4.1e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME31940.1 - 2.8e-05 23.2 0.0 5.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 EME31940.1 - 0.00027 19.6 0.0 0.00038 19.1 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 EME31940.1 - 0.0039 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Mre11_DNA_bind PF04152.9 EME31941.1 - 1.3e-37 129.3 0.3 1.3e-37 129.3 0.2 2.9 2 1 1 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EME31941.1 - 1.8e-19 69.9 2.8 4.4e-19 68.6 1.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME31941.1 - 1.3e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GTP_EFTU PF00009.22 EME31942.1 - 4.1e-44 150.2 0.0 8.4e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EME31942.1 - 9.5e-23 79.8 0.0 2.2e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EME31942.1 - 1.9e-21 75.6 0.0 7.3e-21 73.8 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EME31942.1 - 1.2e-12 47.4 0.0 5.3e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EME31942.1 - 0.00083 19.3 0.0 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EME31942.1 - 0.023 14.7 0.3 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 RNase_PH PF01138.16 EME31943.1 - 6.4e-27 94.4 0.0 1.2e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME31943.1 - 0.029 14.2 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Arf PF00025.16 EME31945.1 - 6.7e-69 230.6 0.1 8e-69 230.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME31945.1 - 2.5e-16 59.5 0.0 2.9e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EME31945.1 - 5.6e-12 45.2 0.0 6.8e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EME31945.1 - 8.4e-11 41.1 0.3 5.8e-08 31.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME31945.1 - 1.3e-10 40.8 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME31945.1 - 1.3e-09 38.5 0.0 1.8e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME31945.1 - 1.9e-07 31.0 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME31945.1 - 0.00012 21.6 0.1 0.0055 16.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EME31945.1 - 0.0037 16.0 0.1 0.033 12.9 0.0 2.3 2 1 1 3 3 3 1 ArgK protein FeoB_N PF02421.13 EME31945.1 - 0.0073 15.5 0.5 0.03 13.5 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EME31945.1 - 0.037 13.9 0.6 0.7 9.8 0.4 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EME31945.1 - 0.053 13.0 0.5 0.25 10.8 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0029 PF01205.14 EME31945.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 MobB PF03205.9 EME31945.1 - 0.14 11.8 0.1 0.83 9.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EME31946.1 - 2.1e-69 232.2 0.1 2.5e-69 231.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME31946.1 - 4e-17 62.0 0.0 4.6e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EME31946.1 - 4.7e-12 45.4 0.1 5.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EME31946.1 - 6.9e-11 41.4 0.3 4.8e-08 32.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME31946.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME31946.1 - 1.1e-09 38.8 0.0 1.5e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME31946.1 - 1.6e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME31946.1 - 0.00013 21.4 0.1 0.0062 15.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EME31946.1 - 0.0014 17.4 0.2 0.01 14.6 0.1 2.3 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 EME31946.1 - 0.0054 16.0 0.4 0.024 13.9 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EME31946.1 - 0.034 14.0 0.6 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 EME31946.1 - 0.041 13.3 0.5 0.23 10.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EME31946.1 - 0.12 12.1 0.1 0.77 9.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0029 PF01205.14 EME31946.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 MOZ_SAS PF01853.13 EME31947.1 - 3.6e-87 290.4 2.9 4.9e-87 290.0 2.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EME31947.1 - 7.3e-20 70.4 0.2 2e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EME31947.1 - 0.0045 17.1 0.1 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rrf2 PF02082.15 EME31947.1 - 0.14 12.2 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PEX11 PF05648.9 EME31948.1 - 1.1e-27 96.7 1.6 1.3e-27 96.5 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Toprim_N PF08275.6 EME31949.1 - 3.1e-34 117.6 0.0 8.4e-34 116.2 0.0 1.7 2 0 0 2 2 2 1 DNA primase catalytic core, N-terminal domain Toprim_4 PF13662.1 EME31949.1 - 4.2e-16 58.7 0.1 8.4e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 EME31949.1 - 2.6e-10 40.4 0.1 8.9e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Toprim-like Toprim PF01751.17 EME31949.1 - 5.8e-08 32.6 0.1 1.7e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.1 EME31949.1 - 8e-05 22.8 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain ubiquitin PF00240.18 EME31950.1 - 3e-35 119.4 0.6 4.3e-35 118.9 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EME31950.1 - 5.4e-30 102.7 12.2 8.6e-30 102.0 8.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EME31950.1 - 8.1e-21 73.4 0.4 1.3e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME31950.1 - 1.5e-06 28.3 0.1 5.8e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME31950.1 - 0.00017 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME31950.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME31950.1 - 0.02 15.0 0.1 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EME31950.1 - 0.033 14.0 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 EME31950.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EME31950.1 - 0.34 10.7 2.2 2.4 8.0 1.5 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EME31950.1 - 1.5 8.1 4.3 2.3 7.5 2.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase EMP24_GP25L PF01105.19 EME31951.1 - 3.6e-38 131.1 1.0 4e-38 130.9 0.0 1.5 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD PhdYeFM_antitox PF02604.14 EME31951.1 - 0.013 15.0 0.6 0.022 14.3 0.4 1.3 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF2730 PF10805.3 EME31951.1 - 0.098 12.4 0.2 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) NMT PF01233.14 EME31952.1 - 6.2e-79 263.2 0.0 9.3e-79 262.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EME31952.1 - 1.9e-75 252.4 0.1 2.6e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EME31952.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME31952.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Peptidase_M16 PF00675.15 EME31953.1 - 5.5e-37 126.7 0.2 2e-35 121.7 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EME31953.1 - 1.1e-24 87.1 1.4 2.4e-14 53.4 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Cylicin_N PF15241.1 EME31953.1 - 0.053 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Cylicin N-terminus Pkinase PF00069.20 EME31954.1 - 4.1e-64 216.2 0.0 1.2e-63 214.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME31954.1 - 8.1e-29 100.4 2.3 1.4e-26 93.1 0.1 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME31954.1 - 0.00019 20.5 0.8 0.011 14.7 0.0 3.1 3 1 1 4 4 4 1 Kinase-like APH PF01636.18 EME31954.1 - 0.00022 21.0 0.2 0.099 12.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.19 EME31954.1 - 0.0026 18.2 0.0 0.0055 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Cpn10 PF00166.16 EME31960.1 - 1.1e-43 147.0 0.0 1.6e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit DUF1754 PF08555.5 EME31961.1 - 0.00016 22.1 19.8 0.0035 17.9 1.6 2.6 2 1 1 3 3 3 2 Eukaryotic family of unknown function (DUF1754) DUF2514 PF10721.4 EME31961.1 - 0.052 13.2 2.9 0.063 12.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) LSM PF01423.17 EME31962.1 - 3e-15 55.5 0.2 3.5e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME31962.1 - 0.0061 16.4 0.1 0.0079 16.0 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Flag1_repress PF03614.8 EME31962.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 Repressor of phase-1 flagellin LSM14 PF12701.2 EME31962.1 - 0.037 13.8 0.2 0.051 13.3 0.1 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain bZIP_1 PF00170.16 EME31963.1 - 7.7e-05 22.5 15.6 7.7e-05 22.5 10.8 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EME31963.1 - 0.00025 21.2 11.8 0.00025 21.2 8.2 2.6 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EME31963.1 - 0.00071 19.3 20.2 0.00071 19.3 14.0 2.8 2 1 1 3 3 3 1 Basic region leucine zipper DUF1992 PF09350.5 EME31963.1 - 0.015 15.0 3.4 0.15 11.8 2.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1992) Pup PF05639.6 EME31963.1 - 4.4 7.8 8.3 3.9 8.0 0.0 3.1 2 1 1 3 3 3 0 Pup-like protein bZIP_2 PF07716.10 EME31964.1 - 7.9e-07 28.8 11.5 1.4e-06 28.0 8.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EME31964.1 - 0.0035 17.2 12.3 0.0035 17.2 8.5 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF3340 PF11818.3 EME31964.1 - 0.1 12.5 3.3 0.16 11.8 2.3 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) zf-HIT PF04438.11 EME31965.1 - 4.1e-08 32.7 4.4 4.1e-08 32.7 3.0 1.8 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.6 EME31965.1 - 6.3e-05 22.4 0.6 9.1e-05 21.9 0.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF329 PF03884.9 EME31965.1 - 0.014 14.9 1.0 0.035 13.6 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-HIT PF04438.11 EME31966.1 - 3.5e-08 32.9 4.4 5.1e-08 32.4 3.0 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 EME31966.1 - 8.2e-05 22.0 0.6 0.00011 21.6 0.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF329 PF03884.9 EME31966.1 - 0.024 14.1 1.0 0.044 13.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2256 PF10013.4 EME31966.1 - 3.3 7.5 4.9 13 5.6 3.4 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_S11 PF00411.14 EME31968.1 - 8.6e-32 109.5 0.2 9.8e-32 109.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 RRM_1 PF00076.17 EME31969.1 - 1.5e-29 101.4 1.8 3.8e-18 64.8 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME31969.1 - 1e-22 79.8 1.7 7.1e-13 48.3 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME31969.1 - 2.7e-10 39.9 2.7 0.0012 18.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME31969.1 - 0.0012 18.5 0.0 0.028 14.1 0.0 2.6 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif ERCC4 PF02732.10 EME31969.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 ERCC4 domain RRM_3 PF08777.6 EME31969.1 - 0.022 14.6 3.5 0.24 11.2 2.1 2.8 2 1 0 2 2 2 0 RNA binding motif Nup35_RRM PF05172.8 EME31969.1 - 0.074 12.8 0.2 4.3 7.1 0.0 2.4 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EME31969.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) FAD_binding_3 PF01494.14 EME31970.1 - 3e-10 39.7 0.1 3.5e-05 23.0 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EME31970.1 - 1.3e-06 28.4 0.1 2.4e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME31970.1 - 0.0001 21.4 0.0 0.00053 19.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EME31970.1 - 0.00051 19.0 0.2 0.00073 18.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME31970.1 - 0.00086 19.1 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME31970.1 - 0.0012 18.7 0.1 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EME31970.1 - 0.0036 17.1 0.1 0.016 15.0 0.1 2.0 2 0 0 2 2 2 1 ThiF family FAD_oxidored PF12831.2 EME31970.1 - 0.0039 16.3 0.3 0.0073 15.4 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EME31970.1 - 0.0052 15.7 0.2 0.026 13.4 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME31970.1 - 0.025 13.4 0.1 0.045 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EME31970.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EME31970.1 - 0.063 11.7 0.1 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EME31970.1 - 0.074 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MiaE_2 PF13794.1 EME31970.1 - 0.17 11.3 0.2 0.48 9.8 0.0 1.7 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Trp_halogenase PF04820.9 EME31970.1 - 0.23 10.0 0.7 3.3 6.2 0.5 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Ribosomal_S4 PF00163.14 EME31971.1 - 8.8e-25 86.9 2.2 1.8e-24 85.9 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EME31971.1 - 2.7e-12 45.9 1.4 5.8e-12 44.8 1.0 1.6 1 0 0 1 1 1 1 S4 domain NOB1_Zn_bind PF08772.6 EME31972.1 - 5.4e-23 80.5 1.7 9.8e-23 79.7 1.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 EME31972.1 - 0.07 12.6 1.2 0.19 11.2 0.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.9 EME31972.1 - 0.084 12.8 0.8 0.23 11.4 0.5 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EME31972.1 - 0.088 12.0 1.8 0.19 10.9 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EME31972.1 - 0.22 11.3 2.1 0.53 10.1 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 EME31972.1 - 0.37 10.4 2.6 1 9.1 0.8 2.5 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rpr2 PF04032.11 EME31972.1 - 0.46 10.3 3.3 1.4 8.8 2.2 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cys_rich_KTR PF14205.1 EME31972.1 - 0.54 9.7 2.8 0.62 9.5 0.5 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR NOB1_Zn_bind PF08772.6 EME31973.1 - 5.1e-23 80.6 1.7 9.3e-23 79.8 1.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 EME31973.1 - 0.067 12.7 1.2 0.18 11.3 0.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.9 EME31973.1 - 0.079 12.9 0.8 0.22 11.4 0.5 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EME31973.1 - 0.084 12.1 1.8 0.18 11.0 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EME31973.1 - 0.21 11.4 2.1 0.51 10.1 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 EME31973.1 - 0.33 10.6 2.6 0.95 9.2 0.8 2.5 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rpr2 PF04032.11 EME31973.1 - 0.38 10.6 3.1 1.1 9.1 2.0 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cys_rich_KTR PF14205.1 EME31973.1 - 0.51 9.8 2.8 0.59 9.6 0.5 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR DUF815 PF05673.8 EME31974.1 - 3.7e-67 225.8 0.0 1.1e-66 224.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.24 EME31974.1 - 8e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME31974.1 - 1.4e-05 24.8 0.0 7.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME31974.1 - 6.3e-05 23.0 3.1 0.00023 21.2 0.2 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EME31974.1 - 6.8e-05 22.7 0.3 0.00021 21.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EME31974.1 - 8.4e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EME31974.1 - 0.00014 21.9 0.6 0.3 11.0 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EME31974.1 - 0.00062 20.5 1.2 0.0021 18.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 EME31974.1 - 0.00069 18.6 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Miro PF08477.8 EME31974.1 - 0.0019 18.6 0.0 0.0049 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 EME31974.1 - 0.005 17.1 0.9 0.23 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EME31974.1 - 0.0055 16.1 0.0 0.042 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EME31974.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EME31974.1 - 0.0059 16.1 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EME31974.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EME31974.1 - 0.022 13.3 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EME31974.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME31974.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EME31974.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME31974.1 - 0.062 13.5 1.0 0.12 12.6 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ArgK PF03308.11 EME31974.1 - 0.069 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 EME31974.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EME31974.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME31974.1 - 0.12 12.0 0.2 2.3 7.8 0.1 2.4 1 1 1 2 2 2 0 NACHT domain MCM PF00493.18 EME31974.1 - 0.12 11.1 0.3 0.45 9.2 0.0 1.8 2 0 0 2 2 2 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 EME31974.1 - 0.15 11.4 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Nucleoplasmin PF03066.10 EME31974.1 - 0.68 9.4 7.6 1.2 8.6 5.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin dCMP_cyt_deam_1 PF00383.17 EME31975.1 - 9.4e-23 79.8 0.1 1.3e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME31975.1 - 4.1e-05 23.2 0.1 5.2e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EME31975.1 - 0.00016 21.5 0.4 0.24 11.2 0.3 2.1 1 1 0 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 EME31975.1 - 0.0094 15.6 0.1 0.037 13.7 0.0 1.9 2 0 0 2 2 2 1 Xanthomonas XOO_2897-like deaminase DTW PF03942.10 EME31975.1 - 0.0095 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 DTW domain OCIA PF07051.6 EME31975.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Proteasome PF00227.21 EME31976.1 - 1.3e-39 135.4 0.0 1.5e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit GalKase_gal_bdg PF10509.4 EME31976.1 - 0.058 12.6 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Abhydrolase_5 PF12695.2 EME31977.1 - 6e-12 45.5 0.0 8.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME31977.1 - 1.8e-10 41.0 0.0 2.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME31977.1 - 2.1e-06 27.4 0.0 6.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EME31977.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EME31977.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase zf-RING_2 PF13639.1 EME31978.1 - 6.9e-12 45.0 9.5 1.3e-11 44.1 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME31978.1 - 6.7e-08 32.5 9.5 3.4e-07 30.2 6.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME31978.1 - 2e-07 30.5 5.5 3.3e-07 29.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME31978.1 - 1.2e-06 28.0 9.3 2e-06 27.3 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME31978.1 - 1.1e-05 25.3 9.4 2e-05 24.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME31978.1 - 0.00015 21.4 7.7 0.00027 20.5 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME31978.1 - 0.0011 18.6 8.0 0.0025 17.4 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EME31978.1 - 0.0027 17.5 4.5 0.028 14.2 3.1 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EME31978.1 - 0.037 13.9 6.6 0.067 13.0 4.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EME31978.1 - 0.084 12.4 1.9 0.21 11.1 1.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 EME31978.1 - 0.71 9.4 4.7 1.6 8.2 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EME31978.1 - 0.85 9.6 5.1 3.2 7.7 3.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EME31978.1 - 9.1 6.4 9.4 21 5.2 6.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.1 EME31979.1 - 1.6e-08 34.2 3.6 3.3e-08 33.2 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME31979.1 - 1.9e-05 24.2 3.2 3.3e-05 23.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME31979.1 - 3.8e-05 23.6 5.7 0.00027 20.9 3.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME31979.1 - 0.00023 21.1 3.2 0.00045 20.1 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME31979.1 - 0.00026 20.6 2.9 0.00057 19.5 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EME31979.1 - 0.0082 15.8 2.1 0.014 15.0 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME31979.1 - 0.031 14.1 0.7 0.062 13.1 0.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EME31979.1 - 0.035 13.8 3.3 0.069 12.8 2.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EME31979.1 - 0.062 13.1 3.0 0.98 9.3 2.1 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Arfaptin PF06456.8 EME31979.1 - 0.11 11.8 0.2 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Arfaptin-like domain FANCL_C PF11793.3 EME31979.1 - 0.37 10.7 2.5 0.89 9.5 1.7 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain UPF0060 PF02694.10 EME31980.1 - 0.0017 18.3 3.3 0.027 14.5 0.5 2.3 1 1 1 2 2 2 2 Uncharacterised BCR, YnfA/UPF0060 family ApoLp-III PF07464.6 EME31980.1 - 0.022 14.7 6.8 0.037 14.0 4.7 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) IncA PF04156.9 EME31980.1 - 0.52 9.8 13.3 0.04 13.5 5.3 2.2 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EME31980.1 - 3.5 8.0 7.3 0.88 9.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Med4 PF10018.4 EME31980.1 - 4.2 6.7 9.3 1.4 8.3 1.5 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SRA1 PF07304.6 EME31981.1 - 4.6e-07 29.6 0.1 2.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.27 EME31981.1 - 8.2e-07 28.6 22.9 0.015 15.1 0.0 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat Sec16_C PF12931.2 EME31981.1 - 1.9e-05 24.5 0.1 3.5e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EME31981.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain tRNA-synt_His PF13393.1 EME31982.1 - 2.1e-44 151.8 0.0 2.8e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EME31982.1 - 9.6e-16 57.5 0.3 1.9e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EME31982.1 - 2.1e-15 56.7 0.0 3.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.2 EME31982.1 - 4.7e-07 29.2 1.4 6.8e-07 28.7 0.2 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 EME31982.1 - 4.7e-07 28.8 0.0 0.0011 17.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EME31982.1 - 0.061 12.5 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) AAA_11 PF13086.1 EME31983.1 - 3.2e-55 187.2 0.0 3.2e-55 187.2 0.0 3.7 3 1 0 3 3 2 1 AAA domain AAA_12 PF13087.1 EME31983.1 - 6.4e-54 182.3 0.0 6.4e-54 182.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EME31983.1 - 2.6e-15 55.9 0.1 3.6e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain R3H PF01424.17 EME31983.1 - 1.2e-11 44.1 0.2 6.3e-11 41.8 0.0 2.4 2 0 0 2 2 1 1 R3H domain AAA_30 PF13604.1 EME31983.1 - 2.8e-09 36.8 0.0 1.9e-07 30.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EME31983.1 - 3.6e-08 33.2 1.5 0.097 12.1 0.0 4.1 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EME31983.1 - 1e-06 28.9 4.4 0.00079 19.5 0.0 4.7 5 2 0 5 5 5 1 AAA domain Helicase_RecD PF05127.9 EME31983.1 - 1.4e-05 24.8 1.7 0.00022 20.8 0.0 3.6 3 1 0 4 4 4 1 Helicase ResIII PF04851.10 EME31983.1 - 0.00081 19.2 0.0 0.00081 19.2 0.0 3.1 2 2 1 3 3 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EME31983.1 - 0.00093 19.2 0.0 0.0034 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EME31983.1 - 0.0017 18.5 0.3 0.013 15.6 0.0 2.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EME31983.1 - 0.0036 17.6 2.4 0.0093 16.2 0.1 3.0 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EME31983.1 - 0.0043 16.4 0.2 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EME31983.1 - 0.0059 16.1 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 EME31983.1 - 0.0068 16.1 0.2 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Flavi_DEAD PF07652.9 EME31983.1 - 0.0071 16.1 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_33 PF13671.1 EME31983.1 - 0.011 15.5 0.1 0.061 13.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME31983.1 - 0.013 15.4 0.7 0.056 13.3 0.0 2.5 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.17 EME31983.1 - 0.019 14.4 0.0 0.52 9.7 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EME31983.1 - 0.021 15.0 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EME31983.1 - 0.021 14.2 0.1 0.067 12.6 0.0 2.0 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain UvrD_C_2 PF13538.1 EME31983.1 - 0.022 14.9 0.0 0.11 12.6 0.0 2.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ArgK PF03308.11 EME31983.1 - 0.031 13.0 0.0 0.12 11.1 0.0 2.0 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EME31983.1 - 0.032 14.1 0.3 0.19 11.6 0.0 2.5 3 0 0 3 3 1 0 AAA domain CbiA PF01656.18 EME31983.1 - 0.059 12.7 0.4 0.21 10.9 0.3 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 EME31983.1 - 0.18 12.0 0.0 0.18 12.0 0.0 4.0 5 0 0 5 5 4 0 ABC transporter AAA_17 PF13207.1 EME31983.1 - 0.56 11.0 6.2 0.1 13.4 0.4 2.9 4 1 0 4 4 1 0 AAA domain DUF4065 PF13274.1 EME31983.1 - 3.2 8.5 10.6 4.9 7.9 3.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) DUF3336 PF11815.3 EME31984.1 - 4e-27 94.5 4.0 1.1e-26 93.0 1.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EME31984.1 - 2e-24 86.6 0.0 4.2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase E2 PF08199.6 EME31984.1 - 0.17 11.5 1.1 16 5.1 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage E2-like protein WD40 PF00400.27 EME31985.1 - 8.9e-34 114.1 26.1 1.7e-07 30.8 0.8 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 EME31985.1 - 0.00068 19.8 0.8 0.45 10.8 0.0 3.2 3 0 0 3 3 3 2 PQQ-like domain VID27 PF08553.5 EME31985.1 - 0.01 14.0 0.1 0.018 13.2 0.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hira PF07569.6 EME31985.1 - 0.064 12.4 0.4 6 6.0 0.0 2.9 2 1 1 3 3 3 0 TUP1-like enhancer of split NAD_binding_1 PF00175.16 EME31986.1 - 7.8e-26 90.7 0.0 1.1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME31986.1 - 1.8e-25 88.9 0.0 2.8e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EME31986.1 - 3.8e-05 23.6 0.0 0.0036 17.2 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Nucleotid_trans PF03407.11 EME31987.1 - 2.7e-41 141.6 0.0 4.4e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RIO1 PF01163.17 EME31988.1 - 3.7e-60 202.5 0.3 3.7e-60 202.5 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EME31988.1 - 0.0076 15.3 0.0 0.028 13.4 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME31988.1 - 0.012 15.4 0.0 5.2 6.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family OS-D PF03392.8 EME31988.1 - 0.029 14.3 2.8 0.071 13.0 1.9 1.7 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Rhodanese PF00581.15 EME31989.1 - 7.9e-08 32.6 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain adh_short PF00106.20 EME31991.1 - 1.5e-26 93.3 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME31991.1 - 2e-14 53.6 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME31991.1 - 8.4e-07 28.9 0.0 1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME31991.1 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 EME31991.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VIT1 PF01988.14 EME31991.1 - 1.9 7.9 4.3 0.77 9.1 0.3 2.0 2 0 0 2 2 2 0 VIT family Tau95 PF09734.4 EME31992.1 - 3.7e-36 125.0 0.0 7.7e-36 123.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF2893 PF11459.3 EME31992.1 - 0.2 11.4 1.6 2.5 7.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) RIC3 PF15361.1 EME31992.1 - 2 8.6 4.5 12 6.1 0.3 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 SNase PF00565.12 EME31993.1 - 3.6e-21 75.4 0.1 5.2e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Arrestin_C PF02752.17 EME31995.1 - 2.9e-07 30.6 1.0 0.009 16.1 0.4 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EME31995.1 - 4.4e-06 26.5 0.0 0.00021 21.1 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain OST3_OST6 PF04756.8 EME31998.1 - 3.1e-22 78.8 1.6 4.6e-22 78.2 1.1 1.3 1 1 0 1 1 1 1 OST3 / OST6 family DUF4583 PF15190.1 EME31998.1 - 0.74 9.4 4.5 1.9 8.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) tRNA-synt_2 PF00152.15 EME31999.1 - 1.4e-70 237.7 0.1 1.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME31999.1 - 2e-11 43.5 0.2 4.4e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME31999.1 - 0.03 13.5 0.1 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF3446 PF11928.3 EME31999.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF4431 PF14485.1 EME31999.1 - 0.095 12.3 0.3 1 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Sld5 PF05916.6 EME32000.1 - 8.5e-05 22.8 3.5 0.0024 18.1 0.4 2.7 2 1 0 2 2 2 1 GINS complex protein TolB_N PF04052.8 EME32000.1 - 0.032 14.2 0.4 4.6 7.3 0.0 2.7 2 1 1 3 3 3 0 TolB amino-terminal domain UAA PF08449.6 EME32001.1 - 3.1e-45 154.4 15.8 3.7e-45 154.1 10.9 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EME32001.1 - 9.2e-05 22.1 5.5 9.2e-05 22.1 3.8 2.2 2 2 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EME32001.1 - 0.0021 18.0 25.2 0.0035 17.3 4.2 2.8 2 1 1 3 3 3 2 EamA-like transporter family DEAD PF00270.24 EME32002.1 - 6.1e-34 116.9 0.1 1.1e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME32002.1 - 1.7e-23 82.2 0.1 3.1e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME32002.1 - 0.0045 16.8 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ctr PF04145.10 EME32003.1 - 8.3 6.4 7.9 0.56 10.2 1.0 2.2 1 1 0 2 2 2 0 Ctr copper transporter family Macoilin PF09726.4 EME32004.1 - 7.5 4.7 15.6 11 4.1 10.8 1.2 1 0 0 1 1 1 0 Transmembrane protein UL73_N PF12522.3 EME32005.1 - 0.0081 15.6 0.3 0.017 14.6 0.2 1.5 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein N terminal Motile_Sperm PF00635.21 EME32006.1 - 7.5e-25 86.6 0.2 1.6e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Atrophin-1 PF03154.10 EME32006.1 - 0.094 10.8 1.9 0.13 10.4 1.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ribosomal_L3 PF00297.17 EME32007.1 - 7.7e-33 114.0 6.7 7.2e-31 107.5 4.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Glutaredoxin PF00462.19 EME32008.1 - 3.7e-19 68.4 0.1 7e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EME32008.1 - 0.00021 21.4 0.4 0.0012 19.0 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 EME32008.1 - 0.00025 21.2 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.15 EME32008.1 - 0.00099 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EME32008.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME32008.1 - 0.0034 17.3 0.1 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EME32008.1 - 0.53 9.8 2.0 1.7 8.2 0.7 2.3 2 1 0 2 2 2 0 Redoxin Abi PF02517.11 EME32009.1 - 7.4e-14 51.6 6.2 7.4e-14 51.6 4.3 1.9 1 1 0 2 2 2 1 CAAX protease self-immunity ADH_N PF08240.7 EME32010.1 - 4.8e-13 48.8 0.2 1.7e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME32010.1 - 2.8e-06 26.9 0.0 8.6e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Myb_DNA-binding PF00249.26 EME32011.1 - 2.1e-33 114.1 5.0 5.1e-17 61.6 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32011.1 - 2.3e-29 101.2 10.7 6e-20 71.1 2.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain TcpQ PF10671.4 EME32011.1 - 0.05 13.4 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q DUF445 PF04286.7 EME32011.1 - 0.12 11.8 1.2 0.15 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Spore_III_AB PF09548.5 EME32011.1 - 0.3 10.8 1.4 1.6 8.4 0.1 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_5 PF13873.1 EME32011.1 - 0.95 9.4 13.5 5.6 6.9 0.1 4.0 2 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EME32011.1 - 2.7 8.1 11.9 1.5 9.0 1.2 3.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Methyltransf_11 PF08241.7 EME32012.1 - 1.3e-16 60.8 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME32012.1 - 4.9e-12 45.8 0.0 7.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32012.1 - 1.7e-10 40.7 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME32012.1 - 1.9e-08 33.7 0.0 2.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EME32012.1 - 2.2e-07 31.1 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME32012.1 - 2.5e-07 31.0 0.0 4.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EME32012.1 - 5.2e-07 29.1 0.0 7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EME32012.1 - 5.6e-07 30.1 0.0 9.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME32012.1 - 8.4e-06 25.0 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME32012.1 - 2.6e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EME32012.1 - 0.0056 17.5 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME32013.1 - 5.6e-20 71.6 0.0 9.6e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME32013.1 - 6.5e-14 51.9 0.0 9.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME32013.1 - 1.7e-13 50.3 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EME32013.1 - 3.5e-11 42.9 0.0 1.3e-10 41.1 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME32013.1 - 1.4e-10 41.5 0.0 2.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME32013.1 - 2e-08 33.6 0.0 3.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EME32013.1 - 2.7e-08 34.3 0.0 4.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME32013.1 - 4e-07 30.3 0.0 6.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME32013.1 - 6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EME32013.1 - 1.9e-05 24.0 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_24 PF13578.1 EME32013.1 - 0.00012 22.9 0.0 0.00025 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EME32013.1 - 0.0025 16.2 0.0 0.0031 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MPC PF03650.8 EME32014.1 - 1.9e-38 131.0 0.2 2.3e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DnaJ PF00226.26 EME32015.1 - 6.8e-24 83.3 0.1 1.3e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME32015.1 - 7.3e-17 61.0 0.1 3.9e-15 55.4 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME32015.1 - 1e-05 25.4 2.2 1e-05 25.4 1.6 1.7 2 0 0 2 2 2 1 DnaJ central domain Ribosomal_L29 PF00831.18 EME32016.1 - 3.8e-22 77.7 2.3 3.8e-22 77.7 1.6 2.1 2 1 1 3 3 3 1 Ribosomal L29 protein Phage_tail_S PF05069.8 EME32016.1 - 0.021 14.5 3.6 0.028 14.1 2.5 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family DUF1823 PF08853.6 EME32016.1 - 0.15 11.7 1.0 0.25 11.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) SbcD_C PF12320.3 EME32016.1 - 0.2 11.6 5.7 1.5 8.9 3.9 2.2 1 1 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_S9 PF00380.14 EME32016.1 - 0.27 11.4 6.4 0.41 10.9 4.4 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 FlxA PF14282.1 EME32016.1 - 0.76 9.7 5.9 0.25 11.3 2.2 1.5 1 1 0 1 1 1 0 FlxA-like protein FliT PF05400.8 EME32016.1 - 7.6 7.0 7.6 25 5.3 0.1 2.5 2 1 0 2 2 2 0 Flagellar protein FliT Cys_Met_Meta_PP PF01053.15 EME32017.1 - 8.6e-97 323.8 0.0 1e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EME32017.1 - 5.6e-08 31.9 0.0 8.9e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME32017.1 - 9.4e-06 24.8 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EME32017.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase UDPG_MGDP_dh_C PF03720.10 EME32017.1 - 0.038 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ODR4-like PF14778.1 EME32018.1 - 1.6e-11 43.5 0.0 2.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Olfactory receptor 4-like USP7_C2 PF14533.1 EME32018.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Tubulin PF00091.20 EME32020.1 - 5e-72 242.2 0.0 7.8e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME32020.1 - 2.8e-48 163.1 0.0 4.2e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME32020.1 - 5.2e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME32020.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MCM PF00493.18 EME32022.1 - 3.8e-135 449.9 0.0 5.2e-135 449.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME32022.1 - 5.7e-18 65.5 0.2 1.8e-17 63.9 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 EME32022.1 - 5.2e-08 32.7 0.0 1.8e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME32022.1 - 1.2e-07 31.1 0.1 4.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EME32022.1 - 3.1e-05 23.5 0.0 0.00023 20.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME32022.1 - 0.0013 18.2 0.0 0.65 9.4 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.24 EME32022.1 - 0.019 15.1 0.0 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EME32022.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Grp1_Fun34_YaaH PF01184.14 EME32023.1 - 7.5e-42 143.0 13.7 9.6e-42 142.6 9.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Arif-1 PF06770.6 EME32023.1 - 0.13 11.6 3.9 0.21 10.9 2.7 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Grp1_Fun34_YaaH PF01184.14 EME32024.1 - 3.6e-43 147.3 14.3 4.6e-43 146.9 9.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Arif-1 PF06770.6 EME32024.1 - 0.068 12.5 6.1 0.11 11.8 4.2 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) MARVEL PF01284.18 EME32025.1 - 0.034 13.9 14.6 0.063 13.1 9.9 1.6 1 1 0 1 1 1 0 Membrane-associating domain PIG-P PF08510.7 EME32025.1 - 3.4 7.3 10.9 2.2 7.9 5.7 2.0 2 0 0 2 2 2 0 PIG-P E1-E2_ATPase PF00122.15 EME32026.1 - 1.4e-18 66.8 0.1 9.8e-18 64.0 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EME32026.1 - 7.2e-14 52.3 0.0 4.7e-13 49.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME32026.1 - 7.4e-13 49.3 0.0 5.6e-06 26.9 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME32026.1 - 4.9e-09 36.0 0.1 1.5e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME32026.1 - 0.0088 15.6 0.3 0.051 13.1 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_1 PF00133.17 EME32027.1 - 5.9e-198 658.6 0.0 6.4e-197 655.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME32027.1 - 4.4e-41 140.1 0.2 4.4e-41 140.1 0.2 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME32027.1 - 1e-13 50.7 3.7 2e-06 26.7 0.0 4.7 5 0 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EME32027.1 - 2.2e-05 23.8 3.9 4.6e-05 22.8 0.0 3.2 3 1 1 4 4 4 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EME32027.1 - 0.00053 19.1 0.1 1.4 7.9 0.0 3.9 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EME32027.1 - 0.0038 16.0 2.5 0.0045 15.8 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (R) ATG16 PF08614.6 EME32028.1 - 0.00069 19.4 39.8 0.00069 19.4 27.6 7.1 2 2 4 6 6 6 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EME32028.1 - 0.0031 17.2 27.1 0.0031 17.2 18.8 7.6 2 1 4 6 6 6 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EME32028.1 - 0.45 8.1 147.8 0.22 9.1 86.7 2.7 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EME32028.1 - 7.2 5.6 38.3 2.8 7.0 1.1 4.8 1 1 3 5 5 5 0 Reovirus sigma C capsid protein GFO_IDH_MocA PF01408.17 EME32029.1 - 2.1e-15 57.2 0.1 5.1e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME32029.1 - 2.9e-05 23.8 0.0 6.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 EME32029.1 - 0.0038 17.6 0.1 0.009 16.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EME32029.1 - 0.014 15.2 0.1 0.06 13.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EME32029.1 - 0.12 11.7 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TRIC PF05197.8 EME32031.1 - 1.6e-09 37.4 1.7 2.9e-09 36.6 1.2 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.8 EME32031.1 - 0.16 11.6 0.1 0.16 11.6 0.0 2.5 2 1 0 2 2 2 0 UPF0126 domain Ank_2 PF12796.2 EME32032.1 - 4.4e-111 363.4 27.3 5.7e-21 74.6 0.6 6.2 3 1 7 10 10 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 EME32032.1 - 1.5e-57 188.6 19.3 1e-08 34.5 0.0 10.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EME32032.1 - 1.3e-44 149.7 8.7 1e-10 41.7 0.3 8.0 6 1 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME32032.1 - 2.5e-40 135.5 10.8 2.1e-08 34.1 0.1 9.1 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME32032.1 - 2.2e-38 126.4 7.9 2.1e-05 24.3 0.0 10.6 11 0 0 11 11 9 6 Ankyrin repeat Arm PF00514.18 EME32032.1 - 3e-27 93.4 11.1 9.8e-10 37.8 0.0 7.6 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME32032.1 - 7.4e-08 32.5 0.0 5.1e-05 23.4 0.0 5.6 6 1 2 8 8 7 3 HEAT repeats HEAT_EZ PF13513.1 EME32032.1 - 0.00018 21.8 9.5 0.0099 16.3 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat DUF937 PF06078.6 EME32032.1 - 0.013 15.7 0.7 0.08 13.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Costars PF14705.1 EME32032.1 - 0.03 14.3 0.0 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Costars HEAT PF02985.17 EME32032.1 - 0.05 13.6 3.5 2.3 8.5 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat AMNp_N PF10423.4 EME32032.1 - 0.052 13.1 0.0 5.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Bacterial AMP nucleoside phosphorylase N-terminus NCA2 PF08637.5 EME32034.1 - 1.8e-27 95.9 8.1 9.1e-27 93.6 4.3 2.6 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 VIGSSK PF14773.1 EME32034.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal EF1G PF00647.14 EME32034.1 - 0.28 10.8 2.5 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain PCI_Csn8 PF10075.4 EME32035.1 - 3.2e-14 52.9 1.7 3.2e-14 52.9 1.2 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Gemin6 PF06372.7 EME32036.1 - 0.00036 19.8 0.3 0.00061 19.1 0.2 1.7 1 1 0 1 1 1 1 Gemin6 protein SNN_transmemb PF09049.5 EME32036.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Stannin transmembrane FMN_dh PF01070.13 EME32036.1 - 0.047 12.5 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AD PF09793.4 EME32036.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain Intimin_C PF07979.6 EME32037.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 1 1 2 2 2 0 Intimin C-type lectin domain DnaJ PF00226.26 EME32038.1 - 1.1e-08 34.7 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EME32038.1 - 3.6e-08 33.2 0.1 4.2e-08 33.0 0.1 1.0 1 0 0 1 1 1 1 Pam16 Syja_N PF02383.13 EME32039.1 - 4.4e-84 281.9 0.9 2.5e-69 233.4 1.3 2.2 1 1 1 2 2 2 2 SacI homology domain B12D PF06522.6 EME32040.1 - 2.1e-10 40.1 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF4164 PF13747.1 EME32041.1 - 0.4 10.8 10.2 0.73 10.0 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF3153 PF11353.3 EME32041.1 - 3.2 7.1 11.0 1 8.7 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) V_ATPase_I PF01496.14 EME32041.1 - 7.5 4.2 16.2 0.16 9.8 4.9 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family LSM PF01423.17 EME32042.1 - 2e-19 68.8 0.9 2.3e-19 68.7 0.6 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EME32042.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 EME32042.1 - 0.072 13.0 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain PS_Dcarbxylase PF02666.10 EME32043.1 - 1.2e-26 93.3 0.0 1.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase eIF-3c_N PF05470.7 EME32043.1 - 0.08 11.0 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PS_Dcarbxylase PF02666.10 EME32044.1 - 1e-38 132.7 0.0 1.3e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase eIF-3c_N PF05470.7 EME32044.1 - 0.15 10.0 0.0 0.21 9.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ANTH PF07651.11 EME32045.1 - 1e-41 142.5 0.0 1.8e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EME32045.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ENTH domain AdoHcyase PF05221.12 EME32046.1 - 6.2e-138 458.1 0.0 7.3e-138 457.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EME32046.1 - 1e-83 279.0 2.7 1.4e-83 278.5 1.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME32046.1 - 1.9e-09 36.9 0.2 3.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EME32046.1 - 0.00023 20.5 0.3 0.00037 19.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EME32046.1 - 0.00023 21.1 1.2 0.0017 18.3 0.8 2.3 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EME32046.1 - 0.0072 15.4 1.8 0.033 13.2 1.3 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EME32046.1 - 0.02 15.1 0.3 0.055 13.7 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME32046.1 - 0.029 14.4 0.7 0.08 13.0 0.5 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EME32046.1 - 0.037 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EME32046.1 - 0.1 12.7 0.3 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein bZIP_1 PF00170.16 EME32047.1 - 0.0058 16.5 2.3 0.013 15.4 1.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor Seryl_tRNA_N PF02403.17 EME32047.1 - 0.024 14.6 0.9 0.075 13.0 0.6 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlgN PF05130.7 EME32047.1 - 0.16 12.2 3.7 0.11 12.7 0.7 2.0 2 0 0 2 2 2 0 FlgN protein APG6 PF04111.7 EME32047.1 - 1.1 8.2 8.6 0.16 10.9 3.1 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 KIAA1430 PF13879.1 EME32047.1 - 8.7 6.8 9.2 0.48 10.8 2.5 1.9 2 0 0 2 2 2 0 KIAA1430 homologue NAD_binding_1 PF00175.16 EME32048.1 - 1.9e-14 54.1 0.0 5e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME32048.1 - 1.1e-13 51.1 0.0 4.5e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Myb_DNA-binding PF00249.26 EME32048.1 - 3.2e-12 46.3 0.1 1.8e-11 43.8 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32048.1 - 0.0024 17.9 1.0 0.0071 16.4 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain NAD_binding_6 PF08030.7 EME32048.1 - 0.0044 16.9 1.6 0.0098 15.8 0.0 2.3 3 0 0 3 3 3 1 Ferric reductase NAD binding domain DUF2052 PF09747.4 EME32049.1 - 2.5e-28 99.2 21.1 1.3e-27 96.8 14.6 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Methyltransf_16 PF10294.4 EME32050.1 - 3.6e-15 55.8 0.0 5.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EME32050.1 - 2.1e-05 25.0 0.0 3.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32050.1 - 0.00048 19.7 0.0 0.00075 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME32050.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EME32050.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME32050.1 - 0.0027 18.1 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME32050.1 - 0.071 13.1 0.0 1.1 9.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.17 EME32051.1 - 2.1e-23 83.1 0.1 3.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME32051.1 - 1.1e-05 25.2 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.15 EME32051.1 - 0.00035 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus PALP PF00291.20 EME32052.1 - 5.2e-72 242.6 0.2 8.1e-72 242.0 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2570 PF10828.3 EME32052.1 - 0.0037 16.8 0.9 0.008 15.7 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF1925 PF09094.6 EME32052.1 - 0.038 13.9 0.2 0.09 12.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1925) DUF1682 PF07946.9 EME32052.1 - 1.8 7.3 6.2 2.9 6.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDP-OH_P_transf PF01066.16 EME32053.1 - 5.6e-15 55.4 1.9 8.7e-15 54.8 1.3 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MOR2-PAG1_mid PF14228.1 EME32053.1 - 0.11 10.0 0.3 0.13 9.8 0.2 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region Asparaginase_2 PF01112.13 EME32054.1 - 1e-55 188.7 0.8 1.7e-55 188.0 0.5 1.3 1 1 0 1 1 1 1 Asparaginase PseudoU_synth_2 PF00849.17 EME32055.1 - 2.5e-30 105.4 0.0 4.4e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EME32055.1 - 0.0022 17.4 0.1 0.0049 16.2 0.1 1.7 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.21 EME32056.1 - 1.5e-21 76.2 0.6 5e-21 74.6 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme BP28CT PF08146.7 EME32056.1 - 2.5e-19 69.5 0.1 2.5e-19 69.5 0.0 4.0 5 0 0 5 5 5 1 BP28CT (NUC211) domain HEAT_2 PF13646.1 EME32056.1 - 0.0082 16.3 0.2 4.3 7.6 0.0 4.8 6 0 0 6 6 6 1 HEAT repeats Fe-ADH PF00465.14 EME32056.1 - 1.7 7.1 0.2 12 4.3 0.0 2.1 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Epimerase PF01370.16 EME32057.1 - 2.8e-17 62.9 0.0 3.2e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME32057.1 - 1.3e-11 44.8 0.0 8e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EME32057.1 - 2.8e-05 23.1 0.0 7.4e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 EME32057.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EME32057.1 - 0.0088 14.7 0.0 0.22 10.2 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.1 EME32057.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HAD_2 PF13419.1 EME32058.1 - 3.4e-20 73.0 0.0 5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME32058.1 - 2.5e-12 47.6 0.0 2e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME32058.1 - 2.9e-09 36.4 0.0 6.6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EME32058.1 - 5.3e-06 26.1 0.0 0.00033 20.3 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.2 EME32058.1 - 0.00012 22.3 0.0 0.00027 21.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME32058.1 - 0.031 14.1 0.0 1.2 9.0 0.0 2.8 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 EME32059.1 - 0.00085 19.1 8.7 0.3 11.0 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat PRKCSH_1 PF13015.1 EME32059.1 - 0.0086 15.5 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TPK_catalytic PF04263.11 EME32060.1 - 1.1e-25 89.5 0.0 1.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EME32060.1 - 2e-18 65.8 0.0 3.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CRAL_TRIO PF00650.15 EME32061.1 - 2e-24 85.9 0.0 2.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EME32061.1 - 2.8e-08 33.8 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME32061.1 - 0.00028 20.9 0.2 0.00076 19.5 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain AAA PF00004.24 EME32062.1 - 2.3e-34 118.4 0.0 2.4e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME32062.1 - 3.6e-06 27.0 0.3 0.0088 16.0 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EME32062.1 - 3.9e-06 26.6 0.0 0.09 12.4 0.0 3.3 2 1 2 4 4 4 2 NACHT domain AAA_17 PF13207.1 EME32062.1 - 5.3e-06 27.2 0.1 4.3e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EME32062.1 - 3.9e-05 23.7 0.2 0.026 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EME32062.1 - 0.0045 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME32062.1 - 0.0071 16.6 0.0 0.021 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME32062.1 - 0.014 15.0 0.0 0.056 13.1 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EME32062.1 - 0.019 14.8 0.0 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME32062.1 - 0.024 14.7 0.2 0.35 11.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 EME32062.1 - 0.031 13.4 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EME32062.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IPT PF01745.11 EME32062.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ATP_bind_1 PF03029.12 EME32062.1 - 0.073 12.6 0.1 0.48 9.9 0.0 2.3 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein ResIII PF04851.10 EME32062.1 - 0.094 12.5 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EME32062.1 - 0.15 11.7 0.0 0.89 9.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Orn_Arg_deC_N PF02784.11 EME32063.1 - 4e-46 157.2 0.0 5.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME32063.1 - 1.3e-12 47.4 0.0 2.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ribosomal_L13 PF00572.13 EME32064.1 - 5.6e-25 87.8 0.2 1.3e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 IF2_N PF04760.10 EME32064.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Abi PF02517.11 EME32065.1 - 1.5e-16 60.2 7.5 1.5e-16 60.2 5.2 2.7 2 2 0 2 2 2 1 CAAX protease self-immunity CBFD_NFYB_HMF PF00808.18 EME32066.1 - 6.5e-08 32.5 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME32066.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME32067.1 - 6.6e-08 32.5 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME32067.1 - 0.00069 19.6 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Thioredoxin PF00085.15 EME32068.1 - 6.7e-11 41.7 0.3 1.1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.1 EME32068.1 - 7.5e-05 22.2 0.4 0.00033 20.2 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin NPL4 PF05021.10 EME32068.1 - 0.025 13.7 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 NPL4 family Pkinase PF00069.20 EME32069.1 - 3.4e-45 154.2 0.8 8.8e-45 152.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32069.1 - 1.4e-17 63.6 0.5 3.1e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.7 EME32069.1 - 1.9e-08 34.1 0.2 4.1e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 RIO1 PF01163.17 EME32069.1 - 0.0023 17.2 0.1 0.007 15.7 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EME32069.1 - 0.0027 16.7 0.0 0.0067 15.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME32069.1 - 0.013 14.5 0.1 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dam PF05869.6 EME32069.1 - 0.015 14.7 1.1 0.16 11.3 0.1 2.3 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) APH PF01636.18 EME32069.1 - 0.037 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1478 PF07349.6 EME32069.1 - 0.065 12.6 0.3 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) PRA1 PF03208.14 EME32070.1 - 4.6e-26 90.9 8.1 6.2e-26 90.5 5.6 1.2 1 0 0 1 1 1 1 PRA1 family protein ICMT PF04140.9 EME32070.1 - 0.0067 16.6 0.3 0.0067 16.6 0.2 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4010 PF13194.1 EME32070.1 - 0.21 10.8 9.8 0.3 10.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Tic20 PF09685.5 EME32070.1 - 6.8 6.7 15.1 6.1 6.8 0.7 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF3216 PF11505.3 EME32072.1 - 0.049 13.4 0.2 2.9 7.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3216) Pep_deformylase PF01327.16 EME32072.1 - 0.061 12.7 0.0 0.076 12.4 0.0 1.0 1 0 0 1 1 1 0 Polypeptide deformylase DUF1268 PF06896.6 EME32072.1 - 0.1 12.9 1.7 0.31 11.3 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1268) Thymosin PF01290.15 EME32072.1 - 0.11 12.1 0.2 0.11 12.1 0.2 2.1 1 1 1 2 2 2 0 Thymosin beta-4 family Baculo_LEF-11 PF06385.7 EME32072.1 - 0.11 12.5 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 Baculovirus LEF-11 protein PGM_PMM_I PF02878.11 EME32073.1 - 4.5e-32 110.4 0.0 7e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EME32073.1 - 1.4e-23 83.1 0.0 2.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EME32073.1 - 5.1e-12 46.0 0.0 1.8e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EME32073.1 - 1.5e-08 34.4 0.0 3.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PRCC PF10253.4 EME32074.1 - 5e-09 37.1 11.2 1.2e-08 35.8 7.8 1.8 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting PfkB PF00294.19 EME32077.1 - 3.3e-66 223.4 0.0 4.1e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EME32077.1 - 0.0057 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RP-C_C PF11800.3 EME32078.1 - 0.064 12.9 1.0 0.12 12.1 0.7 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF515 PF04415.7 EME32078.1 - 0.11 10.6 1.9 0.16 10.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PEMT PF04191.8 EME32079.1 - 2.4e-20 72.6 7.5 2.4e-20 72.6 5.2 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF973 PF06157.6 EME32079.1 - 0.34 9.8 3.7 0.46 9.4 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) PAP2 PF01569.16 EME32080.1 - 3.1e-16 59.2 10.2 3.1e-16 59.2 7.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily Fels1 PF05666.6 EME32080.1 - 0.024 13.9 0.0 0.07 12.5 0.0 1.7 1 1 0 1 1 1 0 Fels-1 Prophage Protein-like NS3_envE PF02723.9 EME32080.1 - 5.4 6.9 10.6 16 5.4 0.5 2.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Dus PF01207.12 EME32081.1 - 7.5e-73 245.0 0.0 9.1e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EME32081.1 - 0.023 13.9 0.0 0.041 13.1 0.0 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 EME32081.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 EME32081.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AP_endonuc_2 PF01261.19 EME32081.1 - 0.1 11.9 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel PALP PF00291.20 EME32082.1 - 3.4e-69 233.4 0.0 3.9e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RNase_PH PF01138.16 EME32083.1 - 1.6e-22 80.2 0.0 2.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME32083.1 - 2.7e-08 33.6 0.0 7.6e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Erv26 PF04148.8 EME32084.1 - 8.5e-45 152.7 3.6 1e-44 152.4 2.5 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 LHC PF00556.15 EME32084.1 - 1.7 8.5 6.7 0.44 10.4 0.5 2.7 1 1 1 2 2 2 0 Antenna complex alpha/beta subunit Auto_anti-p27 PF06677.7 EME32085.1 - 7.2e-20 70.4 7.2 6.4e-12 45.0 1.0 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1737 PF08410.5 EME32085.1 - 0.091 12.5 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) AAA_24 PF13479.1 EME32085.1 - 0.16 11.5 0.1 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rep_fac-A_C PF08646.5 EME32085.1 - 5.7 6.6 8.0 5.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Auto_anti-p27 PF06677.7 EME32086.1 - 1.3e-12 47.2 0.5 2.9e-07 30.1 0.3 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1737 PF08410.5 EME32086.1 - 0.024 14.3 0.0 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) P5-ATPase PF12409.3 EME32086.1 - 0.13 12.1 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter Sec7 PF01369.15 EME32087.1 - 5.8e-59 198.9 0.0 1.3e-58 197.8 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EME32087.1 - 2.3e-05 23.9 0.8 5.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2358 PF10184.4 EME32087.1 - 0.0076 16.1 0.2 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 EME32087.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Rtf2 PF04641.7 EME32088.1 - 1.6e-12 47.1 9.4 9.9e-07 28.2 0.2 3.3 1 1 3 4 4 4 2 Rtf2 RING-finger U-box PF04564.10 EME32088.1 - 9e-07 28.7 0.0 2.6e-05 24.0 0.0 2.9 3 1 0 3 3 3 1 U-box domain zf-Nse PF11789.3 EME32088.1 - 0.00016 21.0 1.0 0.011 15.2 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EME32088.1 - 0.00067 19.4 1.8 0.0036 17.1 0.2 2.4 2 0 0 2 2 2 1 Ring finger domain CENP-Q PF13094.1 EME32088.1 - 0.0057 16.6 5.3 0.0094 15.9 3.7 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_2 PF13923.1 EME32088.1 - 0.039 13.9 0.8 0.039 13.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 EME32088.1 - 0.074 12.8 0.3 0.074 12.8 0.2 1.6 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Mitoc_L55 PF09776.4 EME32088.1 - 0.13 11.8 2.2 0.31 10.6 1.5 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 DUF2570 PF10828.3 EME32088.1 - 0.21 11.2 4.6 0.39 10.3 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Elf1 PF05129.8 EME32088.1 - 7 6.4 7.3 0.22 11.2 0.4 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like PPP4R2 PF09184.6 EME32089.1 - 6.7e-18 65.2 1.7 8.5e-18 64.8 1.2 1.1 1 0 0 1 1 1 1 PPP4R2 Peptidase_C6 PF00851.13 EME32089.1 - 0.015 13.9 0.5 0.018 13.6 0.1 1.2 1 1 0 1 1 1 0 Helper component proteinase Myb_DNA-binding PF00249.26 EME32090.1 - 3.8e-05 23.6 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32090.1 - 0.0087 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF367 PF04034.8 EME32091.1 - 2.6e-44 149.8 0.0 3.9e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EME32091.1 - 2.8e-09 36.4 0.0 4.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI F-box-like PF12937.2 EME32092.1 - 5.5e-08 32.4 0.2 2.4e-07 30.3 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EME32092.1 - 7.5e-07 28.8 9.2 0.013 15.2 0.1 4.6 2 2 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EME32092.1 - 2.8e-06 26.8 5.7 0.046 13.3 0.0 4.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EME32092.1 - 0.00034 20.1 0.9 0.00034 20.1 0.6 4.0 4 0 0 4 4 4 1 F-box domain LRR_6 PF13516.1 EME32092.1 - 0.0018 18.1 13.5 2.6 8.3 0.0 6.8 7 1 0 7 7 7 2 Leucine Rich repeat DUF1699 PF08004.6 EME32092.1 - 0.13 11.8 3.4 25 4.4 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) LRR_1 PF00560.28 EME32092.1 - 0.93 9.7 22.0 3.6 7.9 0.4 8.3 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 EME32092.1 - 8.4 7.0 11.3 36 5.1 0.0 6.5 7 0 0 7 7 7 0 Leucine rich repeat TPT PF03151.11 EME32093.1 - 1.3e-27 96.2 11.4 1.3e-27 96.2 7.9 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME32093.1 - 9e-07 28.9 35.9 0.00062 19.7 12.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EME32093.1 - 2.7e-06 26.5 19.7 5.5e-06 25.5 13.6 1.5 1 1 0 1 1 1 1 UAA transporter family DUF1700 PF08006.6 EME32093.1 - 0.012 14.9 6.9 0.012 14.9 4.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) NAD_kinase PF01513.16 EME32094.1 - 2.4e-52 177.4 0.0 4.4e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase ADK PF00406.17 EME32094.1 - 1.3e-27 96.5 0.0 2.9e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EME32094.1 - 1.6e-07 31.6 0.0 2e-06 28.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EME32094.1 - 1.8e-07 32.0 0.0 7.4e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME32094.1 - 7.6e-06 25.8 0.1 4e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME32094.1 - 0.029 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EME32094.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SKI PF01202.17 EME32094.1 - 0.15 11.9 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase BK_channel_a PF03493.13 EME32095.1 - 1.5e-15 56.9 0.2 4.7e-15 55.3 0.1 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EME32095.1 - 4.1e-14 52.0 10.4 2.2e-13 49.6 7.2 2.4 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.26 EME32095.1 - 0.00034 19.9 12.4 0.00093 18.4 8.6 1.8 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.21 EME32095.1 - 0.0029 17.3 4.1 0.0059 16.3 2.9 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel TrkA_N PF02254.13 EME32095.1 - 0.026 14.5 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DAGAT PF03982.8 EME32096.1 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EME32096.1 - 2.9e-06 26.7 0.2 6.7e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase ALG3 PF05208.8 EME32097.1 - 8.9e-94 314.7 33.1 1.1e-93 314.4 23.0 1.0 1 0 0 1 1 1 1 ALG3 protein PseudoU_synth_1 PF01416.15 EME32098.1 - 9.6e-30 103.1 0.0 2.6e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Apolipoprotein PF01442.13 EME32099.1 - 0.0095 15.4 3.7 0.022 14.3 0.5 2.7 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1515 PF07439.6 EME32099.1 - 0.075 12.8 3.6 8.2 6.2 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF883 PF05957.8 EME32099.1 - 2.2 8.7 5.2 30 5.0 0.3 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) MMR_HSR1 PF01926.18 EME32100.1 - 4.2e-18 65.3 0.0 3.6e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME32100.1 - 7e-11 41.6 0.0 3.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EME32100.1 - 9.5e-05 21.6 0.0 0.00035 19.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EME32100.1 - 0.0017 18.1 0.0 0.012 15.3 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AAA_25 PF13481.1 EME32100.1 - 0.0029 17.0 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME32100.1 - 0.0037 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EME32100.1 - 0.004 16.3 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EME32100.1 - 0.005 17.3 0.0 0.028 14.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EME32100.1 - 0.007 15.8 0.0 3.9 6.8 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EME32100.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain F_actin_bind PF08919.5 EME32100.1 - 0.071 12.8 0.1 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 F-actin binding Arf PF00025.16 EME32100.1 - 0.073 12.3 0.0 0.74 9.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Septin PF00735.13 EME32100.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 EME32100.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 EME32100.1 - 0.11 11.8 0.0 12 5.3 0.0 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EME32101.1 - 3.5e-18 65.6 0.0 3.1e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME32101.1 - 6.1e-11 41.8 0.0 3.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EME32101.1 - 8.4e-05 21.8 0.0 0.00029 20.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EME32101.1 - 0.0015 18.3 0.0 0.0083 15.9 0.0 2.1 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EME32101.1 - 0.0015 17.6 0.0 0.0069 15.5 0.0 2.0 1 1 1 2 2 2 1 AIG1 family AAA_25 PF13481.1 EME32101.1 - 0.0025 17.2 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME32101.1 - 0.0033 17.1 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EME32101.1 - 0.0049 17.3 0.0 0.026 15.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EME32101.1 - 0.0058 16.0 0.0 3.5 6.9 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EME32101.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 EME32101.1 - 0.063 12.5 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 EME32101.1 - 0.091 12.1 0.0 11 5.4 0.0 3.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EME32101.1 - 0.092 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin F_actin_bind PF08919.5 EME32101.1 - 0.097 12.3 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 F-actin binding AAA_10 PF12846.2 EME32101.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Lactamase_B PF00753.22 EME32102.1 - 3.7e-16 59.3 2.6 7.1e-16 58.4 1.8 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME32102.1 - 0.0039 16.7 0.1 0.0048 16.4 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ABC_tran PF00005.22 EME32103.1 - 5.2e-31 107.7 0.0 8.6e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME32103.1 - 3.8e-21 75.7 14.7 6.5e-21 74.9 10.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EME32103.1 - 2.4e-07 31.0 0.1 0.0018 18.2 0.0 2.5 2 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 EME32103.1 - 1e-06 28.1 0.0 0.00031 20.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME32103.1 - 2.8e-06 27.4 0.1 1.2e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EME32103.1 - 0.00018 22.3 0.2 0.00051 20.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME32103.1 - 0.00069 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EME32103.1 - 0.0011 19.1 0.1 0.014 15.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME32103.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME32103.1 - 0.01 16.1 1.6 0.021 15.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EME32103.1 - 0.011 15.1 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME32103.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EME32103.1 - 0.017 14.8 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EME32103.1 - 0.018 14.9 0.3 0.078 12.9 0.2 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME32103.1 - 0.021 14.5 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EME32103.1 - 0.022 14.4 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EME32103.1 - 0.052 12.9 0.1 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 EME32103.1 - 0.064 12.2 0.8 0.17 10.9 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 EME32103.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EME32103.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EME32103.1 - 0.12 11.8 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Lamp PF01299.12 EME32103.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) AAA_28 PF13521.1 EME32103.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EME32103.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain YrhK PF14145.1 EME32104.1 - 0.00016 21.2 8.1 0.0006 19.4 5.6 1.9 1 1 0 1 1 1 1 YrhK-like protein Isochorismatase PF00857.15 EME32105.1 - 1.6e-31 109.6 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Helicase_C PF00271.26 EME32106.1 - 3.2e-21 74.9 0.1 1.2e-20 73.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME32106.1 - 1.2e-16 60.6 0.0 2.7e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EME32106.1 - 1.7e-14 54.0 0.0 7e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATP-sulfurylase PF01747.12 EME32107.1 - 5.9e-60 202.2 0.0 7.8e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EME32107.1 - 9.3e-44 148.6 0.0 2.3e-43 147.3 0.0 1.6 2 0 0 2 2 2 1 PUA-like domain CLTH PF10607.4 EME32108.1 - 0.0079 15.9 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Robl_LC7 PF03259.12 EME32109.1 - 4.2e-05 23.0 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Methyltransf_16 PF10294.4 EME32110.1 - 1e-20 73.8 0.0 2.4e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CDP-OH_P_transf PF01066.16 EME32110.1 - 8.9e-20 70.8 5.5 8.9e-20 70.8 3.8 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase TFIIA PF03153.8 EME32110.1 - 9.2e-14 52.1 0.1 5.3e-08 33.1 0.2 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Methyltransf_18 PF12847.2 EME32110.1 - 0.00043 20.8 0.0 0.00088 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32110.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain HGTP_anticodon2 PF12745.2 EME32110.1 - 0.37 9.8 3.8 0.61 9.1 2.6 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs WLM PF08325.5 EME32111.1 - 8.9e-42 143.0 0.2 1.5e-41 142.3 0.2 1.5 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EME32111.1 - 7.7e-06 25.8 0.3 1.8e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 ketoacyl-synt PF00109.21 EME32113.1 - 1.1e-55 188.8 0.1 1.9e-55 188.1 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EME32113.1 - 4.2e-30 104.0 0.0 1.1e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EME32113.1 - 8.8e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain HpcH_HpaI PF03328.9 EME32114.1 - 1.4e-51 174.4 0.0 2.2e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EME32114.1 - 1e-10 40.9 0.3 3.4e-05 22.8 0.0 2.3 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SNF5 PF04855.7 EME32115.1 - 6.2e-33 114.2 0.8 1.1e-29 103.6 0.6 3.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EME32115.1 - 1.3e-11 43.6 1.3 2.6e-11 42.6 0.9 1.6 1 0 0 1 1 1 1 GATA zinc finger ChaC PF04752.7 EME32116.1 - 1.3e-54 184.8 0.1 1.8e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein SH3_9 PF14604.1 EME32116.1 - 0.15 11.6 1.3 0.36 10.4 0.0 2.3 3 0 0 3 3 3 0 Variant SH3 domain ArsA_ATPase PF02374.10 EME32117.1 - 3.8e-180 597.5 0.0 2.9e-90 302.4 0.0 2.5 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EME32117.1 - 4.3e-32 111.1 0.0 4.9e-17 61.9 0.0 3.2 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME32117.1 - 1.3e-15 57.6 1.8 2.7e-06 27.4 0.1 4.9 4 1 0 4 4 3 2 AAA domain SRP54 PF00448.17 EME32117.1 - 3.4e-09 36.4 0.0 0.0011 18.5 0.0 3.7 4 0 0 4 4 3 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EME32117.1 - 3.2e-08 33.0 0.0 0.0026 17.0 0.0 2.6 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EME32117.1 - 4.5e-08 32.7 0.1 0.0039 16.5 0.0 2.5 2 0 0 2 2 2 2 YhjQ protein AAA_16 PF13191.1 EME32117.1 - 1.6e-07 31.5 0.0 0.015 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EME32117.1 - 1.3e-06 27.9 0.3 0.053 12.9 0.0 4.1 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EME32117.1 - 4.6e-06 25.8 0.0 0.082 11.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EME32117.1 - 6.5e-06 26.4 1.8 0.053 13.8 0.0 3.5 4 1 0 4 4 3 2 AAA domain AAA_19 PF13245.1 EME32117.1 - 2.3e-05 24.0 0.0 0.011 15.4 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 EME32117.1 - 2.4e-05 23.3 0.0 0.19 10.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.1 EME32117.1 - 0.00019 22.2 0.1 0.96 10.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EME32117.1 - 0.00092 19.5 0.1 0.22 11.8 0.0 2.8 3 0 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.12 EME32117.1 - 0.00096 18.6 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_26 PF13500.1 EME32117.1 - 0.0014 18.2 0.8 2.9 7.4 0.1 3.2 4 0 0 4 4 4 2 AAA domain KTI12 PF08433.5 EME32117.1 - 0.0026 16.9 0.0 0.53 9.4 0.0 2.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.4 EME32117.1 - 0.0037 16.2 0.2 4.1 6.2 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EME32117.1 - 0.0038 16.2 0.0 2.7 6.8 0.0 2.5 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EME32117.1 - 0.0039 16.8 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EME32117.1 - 0.011 15.9 0.1 8.9 6.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME32117.1 - 0.011 15.3 0.1 7.4 6.2 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EME32117.1 - 0.012 15.7 0.0 8.9 6.5 0.0 2.9 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.11 EME32117.1 - 0.013 14.7 0.0 1.6 7.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EME32117.1 - 0.019 13.8 0.0 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EME32117.1 - 0.029 13.1 0.3 2.4 6.8 0.0 2.6 3 0 0 3 3 3 0 ArgK protein MipZ PF09140.6 EME32117.1 - 0.035 13.1 0.3 1.7 7.6 0.0 3.1 4 0 0 4 4 4 0 ATPase MipZ Miro PF08477.8 EME32117.1 - 0.048 14.1 0.0 20 5.7 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EME32117.1 - 0.063 12.8 2.0 3.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EME32117.1 - 0.07 12.5 0.2 2.6 7.3 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EME32117.1 - 0.073 12.2 0.7 7.9 5.6 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EME32117.1 - 0.074 12.7 0.1 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 EME32117.1 - 0.078 11.9 0.0 6 5.7 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain Tir_receptor_N PF07490.6 EME32117.1 - 0.095 12.3 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus DGOK PF05035.7 EME32117.1 - 0.11 11.2 0.1 0.67 8.6 0.0 2.0 2 0 0 2 2 2 0 2-keto-3-deoxy-galactonokinase LpxK PF02606.9 EME32117.1 - 0.13 11.2 0.2 5.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase RE_Eco29kI PF09517.5 EME32117.1 - 0.14 11.4 0.2 1.6 7.9 0.0 2.7 2 2 1 3 3 3 0 Eco29kI restriction endonuclease AAA_24 PF13479.1 EME32117.1 - 0.66 9.5 2.2 51 3.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain NAC PF01849.13 EME32118.1 - 2.6e-22 78.0 0.6 4.9e-22 77.2 0.1 1.8 2 0 0 2 2 2 1 NAC domain Peptidase_S9 PF00326.16 EME32120.1 - 4.7e-37 127.2 0.0 7e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME32120.1 - 4.9e-11 42.5 0.0 1.4e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EME32120.1 - 6e-09 35.5 0.0 4.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EME32120.1 - 7.8e-09 35.3 0.2 2.8e-06 26.9 0.4 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EME32120.1 - 1.8e-08 34.5 0.0 4.2e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EME32120.1 - 0.00026 20.7 0.0 0.00093 18.9 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EME32120.1 - 0.061 12.8 0.6 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.15 EME32120.1 - 0.074 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EME32121.1 - 4.7e-37 127.2 0.0 7e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME32121.1 - 4.9e-11 42.5 0.0 1.4e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EME32121.1 - 6e-09 35.5 0.0 4.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EME32121.1 - 7.8e-09 35.3 0.2 2.8e-06 26.9 0.4 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EME32121.1 - 1.8e-08 34.5 0.0 4.2e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EME32121.1 - 0.00026 20.7 0.0 0.00093 18.9 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EME32121.1 - 0.061 12.8 0.6 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.15 EME32121.1 - 0.074 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Branch PF02485.16 EME32125.1 - 3e-17 62.6 0.3 1.7e-14 53.5 0.2 2.1 1 1 0 1 1 1 1 Core-2/I-Branching enzyme ATP_bind_1 PF03029.12 EME32126.1 - 5.8e-58 196.2 0.0 6.6e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EME32126.1 - 0.00012 22.9 0.0 0.00021 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME32126.1 - 0.00015 22.0 0.0 0.00041 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EME32126.1 - 0.00062 19.7 0.0 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME32126.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EME32126.1 - 0.002 17.8 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 EME32126.1 - 0.0022 17.9 0.0 0.0088 15.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EME32126.1 - 0.0023 17.4 0.0 0.008 15.6 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EME32126.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME32126.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EME32126.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EME32126.1 - 0.017 14.8 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.1 EME32126.1 - 0.019 15.0 0.0 0.072 13.2 0.0 1.9 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 EME32126.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME32126.1 - 0.056 13.6 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME32126.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EME32126.1 - 0.066 13.3 0.0 0.44 10.7 0.0 2.3 3 0 0 3 3 3 0 RNA helicase ArgK PF03308.11 EME32126.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 EME32126.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase CLP_protease PF00574.18 EME32127.1 - 3.3e-52 176.8 0.0 7.6e-52 175.6 0.0 1.5 1 1 0 1 1 1 1 Clp protease CLP_protease PF00574.18 EME32128.1 - 3.3e-52 176.8 0.0 7.6e-52 175.6 0.0 1.5 1 1 0 1 1 1 1 Clp protease WD40 PF00400.27 EME32129.1 - 3e-20 71.2 10.0 7.2e-07 28.8 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 EME32129.1 - 0.11 10.2 0.0 2.2 5.9 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Pyr_redox_2 PF07992.9 EME32130.1 - 8.6e-36 123.7 0.0 6.2e-35 120.9 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME32130.1 - 9.6e-20 70.7 2.0 2e-16 60.1 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME32130.1 - 8.7e-14 51.4 0.1 2.3e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.15 EME32130.1 - 5.2e-12 46.1 0.0 2e-11 44.1 0.0 2.1 2 0 0 2 2 1 1 Rhodanese-like domain DAO PF01266.19 EME32130.1 - 2.4e-10 39.8 0.6 0.0038 16.1 0.0 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME32130.1 - 2.1e-07 31.1 0.0 1e-05 25.6 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME32130.1 - 4.5e-06 26.5 2.9 0.0081 16.1 0.2 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME32130.1 - 0.00077 19.2 0.8 6.9 6.4 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EME32130.1 - 0.003 16.5 0.0 0.055 12.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EME32130.1 - 0.011 14.2 1.1 16 3.8 0.0 3.9 3 1 1 4 4 4 0 HI0933-like protein DUF1188 PF06690.6 EME32130.1 - 0.024 13.7 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_binding_2 PF00890.19 EME32130.1 - 0.025 13.4 2.2 9.5 4.9 0.0 3.5 3 1 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.19 EME32130.1 - 0.041 12.9 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EME32130.1 - 0.042 14.1 0.1 8.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EME32130.1 - 0.079 11.8 2.3 0.84 8.4 0.1 3.0 4 0 0 4 4 4 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EME32130.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_1 PF00170.16 EME32131.1 - 2.6 8.0 6.8 10 6.1 0.5 2.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EME32131.1 - 4.2 7.2 6.7 12 5.7 0.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Pkinase PF00069.20 EME32132.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EME32133.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Met_10 PF02475.11 EME32134.1 - 5.3e-56 189.3 0.0 7.2e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EME32134.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EME32134.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EME32135.1 - 6e-56 189.2 0.0 9e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EME32135.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EME32135.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Peptidase_A22B PF04258.8 EME32136.1 - 1.6e-51 175.5 8.3 1.6e-51 175.5 5.7 1.9 2 1 0 2 2 2 1 Signal peptide peptidase CPSF_A PF03178.10 EME32137.1 - 5.7e-49 166.9 0.1 1.6e-48 165.4 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region Ammonium_transp PF00909.16 EME32138.1 - 1.8e-117 392.2 19.6 2.1e-117 392.0 13.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 EME32138.1 - 0.091 12.6 0.7 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Anoctamin PF04547.7 EME32138.1 - 9.8 4.6 7.4 17 3.9 5.1 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel LRR_4 PF12799.2 EME32139.1 - 1.5e-53 177.6 54.9 1.7e-11 43.4 2.1 6.9 5 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME32139.1 - 8.3e-28 95.9 48.8 4.7e-08 32.6 4.5 6.2 1 1 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EME32139.1 - 2.9e-20 69.1 50.8 0.049 13.6 0.1 12.2 11 1 1 12 12 12 9 Leucine Rich Repeat LRR_9 PF14580.1 EME32139.1 - 1.8e-18 66.7 16.6 4.4e-09 36.1 1.0 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 EME32139.1 - 3.8e-15 54.2 38.7 0.13 12.4 0.1 12.3 6 3 6 12 12 12 6 Leucine Rich repeat LRR_7 PF13504.1 EME32139.1 - 1.3e-14 51.6 34.9 0.72 10.3 0.1 12.7 13 0 0 13 13 13 6 Leucine rich repeat DUF2322 PF10084.4 EME32139.1 - 0.036 13.7 1.7 32 4.3 0.0 4.1 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_3 PF07725.7 EME32139.1 - 2.3 8.1 29.2 8.2 6.4 0.2 8.9 9 0 0 9 9 9 0 Leucine Rich Repeat Glyco_hydro_31 PF01055.21 EME32140.1 - 2.2e-142 474.9 7.8 2.8e-142 474.6 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME32140.1 - 2.2e-17 62.6 0.1 8.8e-17 60.7 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like WD40 PF00400.27 EME32141.1 - 3e-84 274.1 27.1 1.6e-11 43.6 0.1 8.7 9 1 0 9 9 9 8 WD domain, G-beta repeat NLE PF08154.7 EME32141.1 - 6.1e-12 45.3 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EME32141.1 - 5.3e-09 34.7 5.4 0.0016 16.6 0.0 5.0 1 1 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EME32141.1 - 5.9e-08 32.6 0.4 0.02 14.5 0.0 3.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EME32141.1 - 7.7e-06 24.9 0.6 0.13 10.9 0.0 3.4 2 2 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EME32141.1 - 0.0034 16.9 6.0 1.1 8.9 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat S1 PF00575.18 EME32142.1 - 8.5e-11 41.7 0.3 1.4e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF676 PF05057.9 EME32143.1 - 5.8e-36 123.8 0.0 8.6e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EME32143.1 - 0.00086 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME32143.1 - 0.0084 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EME32143.1 - 0.031 13.6 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.8 EME32143.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein WD40 PF00400.27 EME32144.1 - 3e-07 30.0 1.4 3.6e-05 23.4 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EME32144.1 - 0.028 14.7 1.1 6.2 7.2 0.0 3.8 3 1 0 3 3 3 0 PQQ-like domain CBS PF00571.23 EME32146.1 - 9.5e-27 92.5 3.9 3.5e-16 58.7 0.2 2.3 2 0 0 2 2 2 2 CBS domain Arc_PepC PF06819.6 EME32146.1 - 0.051 13.5 0.3 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Ribosomal_S3Ae PF01015.13 EME32146.1 - 0.08 12.2 0.3 0.15 11.3 0.2 1.6 1 1 0 1 1 1 0 Ribosomal S3Ae family Flavoprotein PF02441.14 EME32147.1 - 3.6e-42 143.0 0.1 4.6e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein NAD_binding_7 PF13241.1 EME32147.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding TFIID-18kDa PF02269.11 EME32148.1 - 3.1e-21 74.9 0.2 4.2e-21 74.5 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EME32148.1 - 0.041 14.1 1.1 0.067 13.4 0.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.11 EME32149.1 - 6.2e-22 77.2 0.3 7.5e-22 76.9 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EME32149.1 - 0.033 14.4 1.1 0.052 13.8 0.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PCI PF01399.22 EME32150.1 - 1.1e-15 57.8 1.6 1e-14 54.7 0.5 2.7 3 1 0 3 3 3 1 PCI domain ArgJ PF01960.13 EME32151.1 - 1.1e-145 484.9 0.1 1.2e-145 484.7 0.1 1.0 1 0 0 1 1 1 1 ArgJ family RNase_PH PF01138.16 EME32153.1 - 1.2e-24 87.0 0.0 1.6e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MCM PF00493.18 EME32154.1 - 4.9e-97 324.7 0.0 8e-97 323.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME32154.1 - 5.3e-12 46.2 0.1 1.4e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME32154.1 - 7.2e-10 38.3 0.1 1.4e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME32154.1 - 4.9e-09 36.0 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME32154.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME32154.1 - 0.0082 16.2 0.0 0.029 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EME32154.1 - 0.024 14.1 0.1 0.14 11.6 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EME32154.1 - 0.038 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME32154.1 - 0.051 13.5 1.0 0.099 12.6 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EME32154.1 - 0.053 14.0 0.2 0.16 12.4 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein AAA_25 PF13481.1 EME32154.1 - 0.089 12.1 1.5 0.55 9.6 1.1 2.1 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.23 EME32155.1 - 2.5e-94 316.0 0.0 3.2e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32155.1 - 1.9e-20 73.5 0.2 5.1e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AgrB PF04647.10 EME32156.1 - 0.093 11.7 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Rubredoxin PF00301.15 EME32157.1 - 4.6e-19 68.0 1.6 6.7e-19 67.5 1.1 1.2 1 0 0 1 1 1 1 Rubredoxin Elf1 PF05129.8 EME32157.1 - 0.0061 16.2 0.6 0.61 9.8 0.0 2.3 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.7 EME32157.1 - 0.04 13.2 1.7 5.5 6.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.1 EME32157.1 - 0.053 13.1 0.3 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EME32157.1 - 0.1 12.4 0.1 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 EME32157.1 - 0.12 12.1 0.2 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_CPCC PF14206.1 EME32157.1 - 0.23 11.0 1.0 22 4.7 0.1 2.7 2 1 0 2 2 2 0 Cysteine-rich CPCC Spermine_synth PF01564.12 EME32158.1 - 1.9e-61 207.1 0.0 2.4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EME32158.1 - 3.3e-05 24.4 0.0 5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32158.1 - 3.7e-05 23.3 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME32158.1 - 0.00017 21.5 0.0 0.00055 19.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME32158.1 - 0.00047 20.5 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME32158.1 - 0.00077 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME32158.1 - 0.00082 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME32158.1 - 0.0009 18.6 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_30 PF05430.6 EME32158.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF43 PF01861.11 EME32158.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_11 PF08241.7 EME32158.1 - 0.084 13.3 0.0 0.27 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 EME32160.1 - 3.1e-09 36.5 8.6 9.6e-09 34.9 6.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME32160.1 - 5.1e-09 36.1 3.0 1.5e-08 34.5 2.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EME32160.1 - 4.6e-07 29.6 3.8 1.2e-06 28.3 2.7 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EME32160.1 - 6.8e-07 28.8 9.0 1.9e-06 27.3 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME32160.1 - 3.3e-06 26.8 1.7 9.6e-06 25.3 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EME32160.1 - 0.00057 19.8 9.4 0.0022 17.9 6.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME32160.1 - 0.0024 17.5 5.4 0.0085 15.7 3.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_1 PF00667.15 EME32160.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain RINGv PF12906.2 EME32160.1 - 0.024 14.6 7.4 0.074 13.1 5.1 1.9 1 0 0 1 1 1 0 RING-variant domain IBR PF01485.16 EME32160.1 - 0.045 13.6 1.3 0.14 12.0 0.9 1.9 1 0 0 1 1 1 0 IBR domain zf-RING_5 PF14634.1 EME32160.1 - 0.072 12.8 11.2 0.027 14.1 5.3 2.3 2 0 0 2 2 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EME32160.1 - 0.15 11.7 4.2 0.43 10.2 2.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 EME32160.1 - 0.66 9.7 7.8 0.35 10.6 3.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_4 PF15227.1 EME32160.1 - 0.73 9.7 7.8 5.5 6.9 5.4 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EME32160.1 - 1 9.4 7.0 0.2 11.6 2.0 2.0 2 0 0 2 2 1 0 RING-like domain PHD PF00628.24 EME32160.1 - 1 9.1 8.8 0.59 9.8 3.9 2.2 2 0 0 2 2 2 0 PHD-finger zf-Nse PF11789.3 EME32160.1 - 1.7 8.2 4.5 4.1 7.0 3.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD_2 PF13831.1 EME32160.1 - 6.7 6.1 7.6 2.1 7.7 1.9 2.4 2 0 0 2 2 2 0 PHD-finger WD40 PF00400.27 EME32161.1 - 2e-48 160.6 22.8 8.1e-10 38.2 0.1 10.6 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp12 PF04003.7 EME32161.1 - 4.2e-09 36.2 2.0 6.8e-09 35.6 1.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EME32161.1 - 1.1e-05 25.2 0.0 0.4 10.3 0.0 4.7 4 2 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EME32161.1 - 0.0021 17.7 0.1 6.4 6.5 0.0 4.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 EME32161.1 - 0.0046 16.0 0.0 0.074 12.0 0.0 2.4 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Proteasome_A_N PF10584.4 EME32161.1 - 0.016 14.5 10.1 1.4 8.2 0.0 5.2 5 1 1 6 6 6 0 Proteasome subunit A N-terminal signature DUF1513 PF07433.6 EME32161.1 - 0.042 12.7 0.1 4.4 6.1 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) DUF2244 PF10003.4 EME32161.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PQQ_3 PF13570.1 EME32161.1 - 6.2 7.2 7.0 2.9 8.2 0.0 4.0 4 1 1 5 5 5 0 PQQ-like domain MoeA_N PF03453.12 EME32162.1 - 1.1e-36 125.6 0.0 1.7e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EME32162.1 - 7.7e-33 112.9 0.0 1.2e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.10 EME32162.1 - 4.7e-16 58.4 0.0 1.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) AA_kinase PF00696.23 EME32163.1 - 5.1e-13 49.1 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.19 EME32163.1 - 2.3e-10 40.3 0.0 4.6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME32163.1 - 3.4e-09 36.8 0.0 7.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME32163.1 - 9.9e-09 35.2 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME32163.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EME32163.1 - 0.044 13.7 0.1 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME32163.1 - 0.085 12.8 0.0 0.49 10.3 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EME32164.1 - 3.5e-81 272.7 0.1 4.1e-81 272.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32164.1 - 1.4e-19 70.7 0.4 4e-19 69.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YrhK PF14145.1 EME32165.1 - 0.0068 16.0 31.1 0.025 14.2 1.5 5.0 2 2 1 3 3 3 2 YrhK-like protein EMP70 PF02990.11 EME32166.1 - 2.5e-183 610.2 5.5 2.5e-183 610.2 3.8 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 Methyltrans_RNA PF04452.9 EME32167.1 - 1.1e-46 158.7 0.0 1.3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase TspO_MBR PF03073.10 EME32168.1 - 2.1e-16 59.7 3.9 3e-16 59.2 2.7 1.2 1 0 0 1 1 1 1 TspO/MBR family Alpha-amylase PF00128.19 EME32169.1 - 4.8e-18 65.6 0.0 3e-12 46.5 0.0 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF187 PF02638.10 EME32169.1 - 0.005 15.7 0.0 0.0089 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 PAP_fibrillin PF04755.7 EME32170.1 - 1e-33 116.7 0.1 1.9e-33 115.8 0.1 1.4 1 1 0 1 1 1 1 PAP_fibrillin FAD_binding_7 PF03441.9 EME32171.1 - 4.9e-51 173.5 0.0 7.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME32171.1 - 5.8e-31 107.4 0.0 2e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase ESCRT-II PF05871.7 EME32172.1 - 1.5e-49 167.4 0.0 2.1e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit ESCRT-II PF05871.7 EME32173.1 - 1.5e-49 167.4 0.0 2.1e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit UCH PF00443.24 EME32174.1 - 2.9e-50 170.8 0.9 2.9e-50 170.8 0.6 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME32174.1 - 7.3e-29 101.1 2.8 7.3e-29 101.1 1.9 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DnaJ PF00226.26 EME32175.1 - 6.1e-20 70.7 0.3 2e-19 69.0 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain FUSC PF04632.7 EME32175.1 - 1.1 7.5 4.6 1.5 7.1 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sugar_tr PF00083.19 EME32176.1 - 1.1e-90 304.4 23.9 1.7e-90 303.7 16.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME32176.1 - 2.7e-32 111.8 23.2 2.7e-32 111.8 16.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME32176.1 - 1.2e-06 27.0 1.3 1.2e-06 27.0 0.9 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EME32176.1 - 0.0092 15.7 5.2 0.0098 15.6 0.4 2.7 2 0 0 2 2 2 1 MFS_1 like family Orn_Arg_deC_N PF02784.11 EME32177.1 - 5e-50 170.0 0.0 8.9e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME32177.1 - 7e-20 70.8 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 EME32177.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 Alanine racemase, N-terminal domain TIP41 PF04176.8 EME32178.1 - 1.4e-24 86.3 0.0 1.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family FA_desaturase PF00487.19 EME32179.1 - 9.7e-17 61.2 28.9 1.5e-16 60.6 20.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EME32179.1 - 4.2e-16 58.5 0.0 9.9e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thg1C PF14413.1 EME32180.1 - 1.2e-42 144.4 0.6 1.4e-42 144.1 0.4 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EME32180.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Xpo1 PF08389.7 EME32180.1 - 0.081 12.8 0.6 7.5 6.4 0.1 2.2 1 1 1 2 2 2 0 Exportin 1-like protein Med19 PF10278.4 EME32181.1 - 0.0037 16.9 9.9 0.0037 16.9 6.8 2.8 4 0 0 4 4 4 1 Mediator of RNA pol II transcription subunit 19 DUF1515 PF07439.6 EME32181.1 - 0.67 9.7 5.5 0.23 11.3 0.4 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1515) ABC_membrane PF00664.18 EME32182.1 - 1.8e-54 185.0 24.5 6e-32 111.1 4.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME32182.1 - 2.8e-48 163.7 0.0 2e-29 102.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME32182.1 - 4e-09 36.0 0.9 0.076 12.2 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EME32182.1 - 8.9e-05 22.4 2.8 0.0074 16.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_21 PF13304.1 EME32182.1 - 9.4e-05 22.5 0.4 4.1 7.2 0.1 4.0 2 2 1 4 4 4 1 AAA domain Miro PF08477.8 EME32182.1 - 0.00055 20.4 0.3 0.97 9.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EME32182.1 - 0.00081 18.8 0.2 0.62 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EME32182.1 - 0.0013 18.2 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EME32182.1 - 0.0015 17.2 0.1 0.0031 16.1 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 EME32182.1 - 0.0019 17.7 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EME32182.1 - 0.0021 18.0 1.5 0.2 11.5 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EME32182.1 - 0.0059 15.2 0.5 1 7.9 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 EME32182.1 - 0.0072 16.3 2.6 0.1 12.5 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 EME32182.1 - 0.0089 15.8 2.5 0.19 11.5 0.2 2.5 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 EME32182.1 - 0.0091 16.3 1.1 8.9 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EME32182.1 - 0.013 15.1 0.5 3 7.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EME32182.1 - 0.019 13.8 0.0 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EME32182.1 - 0.021 14.5 2.0 0.048 13.4 0.1 2.7 3 0 0 3 3 2 0 Part of AAA domain Zeta_toxin PF06414.7 EME32182.1 - 0.022 13.8 0.1 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EME32182.1 - 0.026 14.1 0.7 11 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EME32182.1 - 0.039 13.1 0.1 7.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Herpes_LMP1 PF05297.6 EME32182.1 - 0.049 12.5 1.4 0.14 11.0 1.0 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) AAA_22 PF13401.1 EME32182.1 - 0.14 12.2 0.4 3.7 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EME32182.1 - 0.25 10.7 1.0 0.84 9.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EME32182.1 - 0.62 10.8 4.5 15 6.3 0.1 3.4 2 1 1 3 3 3 0 AAA domain PK PF00224.16 EME32185.1 - 1.4e-83 280.4 0.3 2.3e-83 279.6 0.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EME32185.1 - 4.8e-21 74.4 0.0 1.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EME32185.1 - 8.1e-07 28.1 0.3 2.6e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family 5-FTHF_cyc-lig PF01812.15 EME32186.1 - 5.3e-46 156.7 0.0 6e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family FGGY_N PF00370.16 EME32186.1 - 0.018 14.3 0.1 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_S17e PF00833.13 EME32187.1 - 4.1e-61 204.1 0.5 4.6e-61 203.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mito_fiss_Elm1 PF06258.6 EME32188.1 - 3.8e-45 154.1 0.0 6.2e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Isochorismatase PF00857.15 EME32188.1 - 3.5e-26 92.1 0.1 7.2e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 Isochorismatase family TAFII55_N PF04658.8 EME32189.1 - 2.3e-21 75.9 2.6 4e-21 75.1 0.0 2.4 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF892 PF05974.7 EME32189.1 - 0.0033 17.2 6.0 0.0033 17.2 4.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF892) Phage_lysis PF03245.8 EME32189.1 - 0.11 12.4 10.0 0.3 11.0 6.9 1.7 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein YojJ PF10372.4 EME32189.1 - 0.12 12.2 1.3 0.3 10.9 0.9 1.8 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus ABC_tran_2 PF12848.2 EME32189.1 - 0.44 10.4 13.6 1 9.2 9.4 1.7 1 0 0 1 1 1 0 ABC transporter DUF4363 PF14276.1 EME32189.1 - 0.72 9.5 9.3 1.7 8.3 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) WD40 PF00400.27 EME32190.1 - 1.2e-10 40.8 9.1 0.0001 22.0 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EME32190.1 - 1.1e-06 27.1 0.2 0.0051 15.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EME32190.1 - 0.00028 20.4 0.2 0.55 9.6 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EME32190.1 - 0.001 17.9 0.8 0.32 9.7 0.0 3.4 4 0 0 4 4 4 2 Nup133 N terminal like LIM PF00412.17 EME32191.1 - 0.1 12.7 0.3 0.1 12.7 0.2 3.3 3 1 0 3 3 3 0 LIM domain GST_N_3 PF13417.1 EME32192.1 - 4.5e-15 55.6 0.1 7.6e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME32192.1 - 4.6e-09 36.1 0.0 8.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME32192.1 - 5.6e-09 35.7 0.1 4.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME32192.1 - 1.4e-08 34.8 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME32192.1 - 4e-05 24.0 0.1 9.3e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME32192.1 - 9.4e-05 22.3 0.0 0.00027 20.8 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.23 EME32193.1 - 2.4e-41 141.4 0.0 3.7e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32193.1 - 7.3e-08 33.2 0.1 2.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Homeobox_KN PF05920.6 EME32194.1 - 1.3e-13 50.3 0.0 2.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EME32194.1 - 1.5e-10 40.4 0.6 2.9e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Homeobox domain Med1 PF10744.4 EME32195.1 - 0.0045 15.8 4.8 0.078 11.7 0.1 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 TraP PF07296.6 EME32196.1 - 0.0051 15.8 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 TraP protein AAA_23 PF13476.1 EME32196.1 - 0.016 15.5 3.6 0.021 15.1 2.5 1.2 1 0 0 1 1 1 0 AAA domain MobC PF05713.6 EME32196.1 - 0.039 13.9 0.4 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) Spc7 PF08317.6 EME32196.1 - 0.058 12.0 9.5 0.086 11.4 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATP-synt_E PF05680.7 EME32196.1 - 0.11 12.4 0.3 0.11 12.4 0.2 2.7 2 1 1 3 3 3 0 ATP synthase E chain Phage_NinH PF06322.6 EME32196.1 - 0.15 11.7 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein Bap31 PF05529.7 EME32196.1 - 0.3 10.5 6.3 0.084 12.3 2.2 1.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Pox_A_type_inc PF04508.7 EME32196.1 - 0.36 10.7 5.5 0.37 10.6 1.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Enkurin PF13864.1 EME32196.1 - 2.1 8.5 8.6 3.5 7.8 5.9 1.4 1 0 0 1 1 1 0 Calmodulin-binding Sod_Fe_C PF02777.13 EME32197.1 - 1.7e-39 133.9 0.1 2.9e-39 133.1 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EME32197.1 - 5.9e-32 109.7 6.0 1.1e-31 108.8 2.1 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RVT_N PF13655.1 EME32197.1 - 0.16 12.0 2.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase Chloroa_b-bind PF00504.16 EME32198.1 - 0.091 13.0 0.0 0.24 11.6 0.0 1.7 1 1 1 2 2 2 0 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.16 EME32199.1 - 0.086 13.0 0.0 0.22 11.7 0.0 1.6 1 1 1 2 2 2 0 Chlorophyll A-B binding protein DUF3598 PF12204.3 EME32200.1 - 0.019 14.1 0.1 0.35 10.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3598) His_Phos_1 PF00300.17 EME32201.1 - 1.6e-13 51.0 0.0 2.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PRELI PF04707.9 EME32202.1 - 1.6e-39 134.9 0.0 2e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF883 PF05957.8 EME32202.1 - 0.11 12.9 0.2 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PRELI PF04707.9 EME32203.1 - 1.6e-39 134.9 0.0 2e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family DUF883 PF05957.8 EME32203.1 - 0.11 12.9 0.2 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Methyltransf_21 PF05050.7 EME32204.1 - 6.1e-19 68.5 0.0 9.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.1 EME32204.1 - 0.0093 15.5 0.2 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DrsE PF02635.10 EME32204.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF-like family Pkinase PF00069.20 EME32205.1 - 1e-54 185.4 0.0 1.7e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32205.1 - 8.2e-50 169.2 0.0 1.1e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME32205.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family GluR_Homer-bdg PF10606.4 EME32206.1 - 0.026 14.4 0.2 0.056 13.3 0.2 1.6 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor Mtp PF03821.11 EME32206.1 - 0.11 11.8 0.3 0.14 11.5 0.2 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Ribosomal_S5 PF00333.15 EME32207.1 - 8.2e-29 99.1 2.3 8.2e-29 99.1 1.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EME32207.1 - 1.6e-23 81.7 0.1 2.9e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Aldo_ket_red PF00248.16 EME32208.1 - 3.6e-51 173.6 0.0 4.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family eIF-1a PF01176.14 EME32209.1 - 9.7e-12 44.1 0.1 2e-11 43.0 0.1 1.5 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 eIF-1a PF01176.14 EME32210.1 - 6.4e-12 44.7 0.1 1.4e-11 43.6 0.1 1.5 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 RRM_1 PF00076.17 EME32212.1 - 3.7e-19 68.1 0.0 1.7e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32212.1 - 1.9e-12 46.9 0.1 1.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME32212.1 - 2.5e-06 27.2 0.0 0.069 13.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EME32213.1 - 1.2e-14 54.0 5.3 1.7e-14 53.5 3.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 EME32213.1 - 0.1 12.5 1.6 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EME32214.1 - 6.6e-13 48.4 4.3 1.1e-12 47.7 3.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ECH PF00378.15 EME32215.1 - 1.1e-38 132.7 0.0 1.4e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SeqA PF03925.8 EME32215.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SeqA protein BRK PF07533.11 EME32217.1 - 1.7e-08 33.7 0.1 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 BRK domain Img2 PF05046.9 EME32217.1 - 0.0088 16.2 1.3 6.7 7.0 0.0 3.1 2 1 1 3 3 3 2 Mitochondrial large subunit ribosomal protein (Img2) DUF4285 PF14113.1 EME32217.1 - 0.13 12.2 2.2 2.8 7.9 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4285) DUF3015 PF11220.3 EME32219.1 - 0.046 13.3 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) Antimicrobial_1 PF08018.6 EME32220.1 - 0.76 9.7 4.5 0.3 11.0 0.4 2.4 2 0 0 2 2 2 0 Frog antimicrobial peptide DUF3147 PF11345.3 EME32220.1 - 4.8 7.2 30.0 0.47 10.4 8.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3147) NADH-u_ox-rdase PF10785.4 EME32221.1 - 2e-10 40.7 0.2 2.5e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit tRNA-synt_2b PF00587.20 EME32222.1 - 3e-45 153.9 0.2 5.9e-45 152.9 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME32222.1 - 9.3e-19 67.1 0.7 2e-18 66.1 0.5 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EME32222.1 - 2.9e-14 52.6 0.0 5.7e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EME32222.1 - 4.1e-08 32.9 0.0 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain NIF PF03031.13 EME32223.1 - 3.4e-23 82.0 1.3 6.8e-23 81.0 0.2 1.9 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase PGP_phosphatase PF09419.5 EME32223.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase ubiquitin PF00240.18 EME32223.1 - 0.0031 16.8 0.0 0.0063 15.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TPR_11 PF13414.1 EME32224.1 - 1.3e-21 76.0 7.3 1.9e-16 59.4 0.5 3.0 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EME32224.1 - 1.4e-16 58.9 6.9 2e-05 24.1 0.6 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat zf-CCCH PF00642.19 EME32224.1 - 4.2e-16 58.1 13.8 3.9e-10 39.1 1.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_1 PF00515.23 EME32224.1 - 1.3e-12 46.7 8.5 0.00036 20.0 0.2 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME32224.1 - 1.9e-07 30.3 4.7 0.053 13.3 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME32224.1 - 1.2e-06 28.1 4.2 0.0012 18.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME32224.1 - 2.9e-06 27.1 8.9 0.00014 21.6 0.7 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME32224.1 - 4.4e-06 27.2 6.2 0.00078 20.0 0.8 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME32224.1 - 0.001 18.8 2.2 0.0071 16.1 0.3 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EME32224.1 - 0.0096 16.0 4.8 0.056 13.5 0.8 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EME32224.1 - 0.012 15.3 2.8 2.2 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME32224.1 - 0.083 13.5 0.7 13 6.7 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EME32224.1 - 0.23 11.3 3.4 6.4 6.7 0.3 3.1 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain LRV_FeS PF05484.6 EME32224.1 - 0.3 10.6 3.2 5.5 6.6 0.1 2.4 1 1 1 2 2 2 0 LRV protein FeS4 cluster TPR_19 PF14559.1 EME32224.1 - 1.8 8.9 4.7 3.5 8.0 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME32224.1 - 6.7 6.7 5.9 35 4.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Synaptobrevin PF00957.16 EME32225.1 - 1e-28 98.7 1.8 1.5e-28 98.1 1.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EME32225.1 - 4.6e-22 77.3 0.0 1.1e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.8 EME32225.1 - 0.00042 19.8 0.6 0.00051 19.5 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MVP_shoulder PF11978.3 EME32225.1 - 0.064 13.1 0.4 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Shoulder domain EVI2A PF05399.6 EME32225.1 - 0.068 12.4 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF872 PF05915.7 EME32225.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) ETRAMP PF09716.5 EME32225.1 - 0.17 11.8 2.1 0.17 11.8 0.4 1.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.6 EME32225.1 - 0.21 11.4 1.4 0.42 10.4 1.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 COX4_pro_2 PF07835.7 EME32225.1 - 0.35 10.8 3.5 0.6 10.1 2.4 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Prominin PF05478.6 EME32225.1 - 0.61 7.5 7.5 2.1 5.7 0.2 2.0 1 1 1 2 2 2 0 Prominin Methyltransf_31 PF13847.1 EME32226.1 - 0.0022 17.6 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PDCD2_C PF04194.8 EME32227.1 - 2.9e-32 111.5 4.1 9.1e-32 109.9 1.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 EME32227.1 - 3e-06 27.0 17.7 3e-06 27.0 12.2 3.3 4 0 0 4 4 4 1 MYND finger Biotin_lipoyl PF00364.17 EME32228.1 - 3.8e-12 45.6 0.3 6.3e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EME32228.1 - 3.6e-05 23.3 0.2 7.8e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.2 EME32228.1 - 0.006 15.7 0.1 0.006 15.7 0.1 2.3 1 1 3 4 4 4 1 HlyD family secretion protein RnfC_N PF13375.1 EME32228.1 - 0.02 14.5 2.7 0.44 10.2 0.1 2.9 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EME32228.1 - 0.055 12.7 0.1 0.055 12.7 0.1 1.6 2 0 0 2 2 2 0 HlyD family secretion protein tRNA-synt_2d PF01409.15 EME32230.1 - 2.5e-52 177.5 0.1 3.6e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EME32230.1 - 5.6e-23 80.9 0.2 1.5e-22 79.5 0.1 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EME32230.1 - 0.024 13.4 0.1 4.7 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Pcc1 PF09341.5 EME32230.1 - 0.092 12.7 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcription factor Pcc1 Glyco_transf_8 PF01501.15 EME32231.1 - 3.8e-20 72.2 0.6 6.2e-20 71.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 EF-hand_1 PF00036.27 EME32232.1 - 2.7e-23 79.4 10.4 1.3e-06 27.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EME32232.1 - 2.8e-21 75.4 8.8 2.9e-10 40.1 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EME32232.1 - 4.1e-18 63.5 7.8 2.4e-06 26.9 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EME32232.1 - 2.4e-16 59.0 12.7 1e-07 31.4 0.2 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EME32232.1 - 6.5e-10 37.8 16.8 4.2e-05 22.7 0.3 4.7 5 1 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 EME32232.1 - 1.4e-08 34.5 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EME32232.1 - 0.00034 20.2 2.3 0.0038 16.9 0.1 2.6 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Toprim_2 PF13155.1 EME32232.1 - 0.069 13.4 1.0 2.9 8.2 0.1 2.7 1 1 1 2 2 2 0 Toprim-like DUF4373 PF14297.1 EME32232.1 - 0.091 13.0 3.0 42 4.5 0.1 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4373) SPOUT_MTase PF02590.12 EME32232.1 - 0.14 11.9 0.2 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase TerB PF05099.8 EME32232.1 - 0.14 11.8 2.7 7.8 6.2 0.0 2.9 2 1 1 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.12 EME32232.1 - 1.1 9.6 5.4 2.3 8.5 2.2 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain ADK PF00406.17 EME32233.1 - 1.7e-30 105.8 0.3 8.9e-18 64.6 0.1 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EME32233.1 - 2.9e-07 31.3 0.0 1.5e-05 25.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EME32233.1 - 7.6e-06 26.2 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ADK_lid PF05191.9 EME32233.1 - 9.2e-06 25.2 0.1 2.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Rad17 PF03215.10 EME32233.1 - 0.00015 20.6 1.6 0.00021 20.1 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EME32233.1 - 0.00021 21.1 0.5 0.012 15.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EME32233.1 - 0.0088 16.2 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EME32233.1 - 0.022 15.0 0.1 0.13 12.5 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_5 PF07728.9 EME32233.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EME32233.1 - 0.13 12.1 0.1 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME32233.1 - 0.14 11.9 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Oxysterol_BP PF01237.13 EME32234.1 - 6.9e-93 310.9 0.0 9e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein LpxB PF02684.10 EME32235.1 - 0.00011 20.9 0.0 0.36 9.4 0.0 3.0 1 1 2 3 3 3 3 Lipid-A-disaccharide synthetase Band_7 PF01145.20 EME32236.1 - 4.1e-25 88.7 4.6 5.2e-25 88.3 2.5 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EME32236.1 - 0.0034 16.3 3.0 0.0047 15.8 2.1 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PAP2 PF01569.16 EME32237.1 - 4.4e-13 49.0 6.5 4.4e-13 49.0 4.5 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF165 PF02592.10 EME32237.1 - 0.007 16.5 2.3 0.34 11.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized ACR, YhhQ family COG1738 GLTSCR1 PF15249.1 EME32238.1 - 8.1e-14 51.6 1.7 1.5e-13 50.8 0.2 2.1 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region DUF1539 PF07560.6 EME32238.1 - 0.024 14.4 0.3 0.63 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) ABC_membrane_2 PF06472.10 EME32239.1 - 1e-53 182.3 13.4 1.4e-53 181.8 9.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME32239.1 - 5.2e-19 68.9 0.0 1.4e-18 67.5 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SbmA_BacA PF05992.7 EME32239.1 - 1.2e-07 31.2 14.2 6.1e-07 28.9 9.9 1.8 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_22 PF13401.1 EME32239.1 - 0.00021 21.4 0.0 0.00074 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME32239.1 - 0.00033 19.8 0.1 0.00064 18.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EME32239.1 - 0.00044 20.7 0.1 0.04 14.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EME32239.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family SMC_N PF02463.14 EME32239.1 - 0.0032 16.7 0.6 0.042 13.0 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME32239.1 - 0.004 17.1 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME32239.1 - 0.0064 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EME32239.1 - 0.01 15.7 0.1 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EME32239.1 - 0.012 15.2 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 EME32239.1 - 0.045 12.6 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EME32239.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME32239.1 - 0.07 12.5 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.1 EME32239.1 - 0.093 12.6 0.1 0.093 12.6 0.0 4.0 3 2 1 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 EME32239.1 - 0.095 12.6 0.1 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase p450 PF00067.17 EME32240.1 - 2.1e-74 250.7 0.0 2.4e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EME32241.1 - 6.6e-13 48.6 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME32241.1 - 1.5e-12 47.7 0.0 4.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32241.1 - 2.8e-09 36.7 0.0 8e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EME32241.1 - 5e-08 32.3 0.0 9.8e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Peptidase_M41 PF01434.13 EME32241.1 - 1.1e-05 25.0 0.0 0.00014 21.4 0.0 2.1 1 1 1 2 2 2 1 Peptidase family M41 Methyltransf_18 PF12847.2 EME32241.1 - 0.00013 22.5 0.0 0.00036 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_M50 PF02163.17 EME32241.1 - 0.00027 19.9 0.0 0.00083 18.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M50 Methyltransf_25 PF13649.1 EME32241.1 - 0.003 17.9 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME32241.1 - 0.0045 17.4 0.0 0.0096 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME32241.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EME32241.1 - 0.067 11.5 0.0 0.094 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tic22 PF04278.7 EME32242.1 - 1.6e-48 165.3 0.1 1.9e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Tic22-like family Prefoldin_2 PF01920.15 EME32243.1 - 2e-19 69.2 13.1 2.4e-19 69.0 9.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 EME32243.1 - 0.0012 18.7 0.7 0.0012 18.7 0.5 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tox-URI2 PF15653.1 EME32243.1 - 0.011 15.9 0.6 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 URI fold toxin 2 DivIC PF04977.10 EME32243.1 - 0.03 13.7 1.6 0.03 13.7 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator IncA PF04156.9 EME32243.1 - 0.037 13.6 10.8 0.044 13.3 7.5 1.2 1 0 0 1 1 1 0 IncA protein Rho_Binding PF08912.6 EME32243.1 - 0.05 13.9 3.0 0.05 13.9 2.1 2.4 2 0 0 2 2 2 0 Rho Binding HR1 PF02185.11 EME32243.1 - 0.092 12.4 8.1 0.15 11.8 0.6 2.3 2 0 0 2 2 2 0 Hr1 repeat MogR_DNAbind PF12181.3 EME32243.1 - 0.1 12.3 4.6 0.14 11.9 3.2 1.1 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Serine_rich PF08824.5 EME32243.1 - 0.11 12.1 3.0 6 6.5 0.7 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF2452 PF10504.4 EME32243.1 - 0.13 11.5 1.6 0.18 11.0 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2452) Microtub_assoc PF07989.6 EME32243.1 - 0.16 11.8 12.5 0.15 11.9 1.9 2.3 2 0 0 2 2 2 0 Microtubule associated CHASE3 PF05227.8 EME32243.1 - 0.35 10.5 5.6 0.66 9.6 2.1 2.0 1 1 0 2 2 2 0 CHASE3 domain V_ATPase_I PF01496.14 EME32243.1 - 1.2 6.8 6.5 1.4 6.6 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRCC4 PF06632.7 EME32243.1 - 1.3 7.8 9.4 0.077 11.8 1.2 1.9 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Lge1 PF11488.3 EME32243.1 - 2.1 8.5 7.3 0.95 9.6 0.4 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Prefoldin PF02996.12 EME32243.1 - 2.7 7.6 11.3 0.28 10.8 2.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit Nsp1_C PF05064.8 EME32243.1 - 2.8 7.6 9.2 0.32 10.6 0.5 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Seryl_tRNA_N PF02403.17 EME32243.1 - 3.3 7.7 13.1 1.5e+02 2.4 9.1 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4047 PF13256.1 EME32243.1 - 4.1 7.3 9.1 0.54 10.2 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) DMPK_coil PF08826.5 EME32243.1 - 4.7 7.1 12.5 0.12 12.3 1.8 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF2360 PF10152.4 EME32243.1 - 4.8 7.4 5.8 1 9.6 0.4 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Remorin_C PF03763.8 EME32243.1 - 5.1 6.6 8.7 0.65 9.5 1.9 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region Adeno_PIX PF03955.9 EME32243.1 - 7.1 7.2 6.6 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF972 PF06156.8 EME32243.1 - 7.4 6.9 11.7 8.7 6.7 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EME32243.1 - 8.5 6.8 8.2 20 5.7 1.3 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PRA1 PF03208.14 EME32244.1 - 5.7e-16 58.2 10.1 9.2e-16 57.5 7.0 1.2 1 0 0 1 1 1 1 PRA1 family protein SNF2_N PF00176.18 EME32245.1 - 4.2e-55 186.6 0.0 6.8e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME32245.1 - 2.9e-08 33.4 0.0 7.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box PF00646.28 EME32245.1 - 2e-05 24.1 0.1 8.2e-05 22.1 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME32245.1 - 0.0019 17.8 0.9 0.0061 16.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like ResIII PF04851.10 EME32245.1 - 0.0086 15.9 0.0 4.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Glu-tRNAGln PF02686.10 EME32246.1 - 1.6e-16 59.8 0.2 2.3e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF1456 PF07308.8 EME32246.1 - 0.093 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DUF848 PF05852.6 EME32246.1 - 0.11 12.2 0.1 0.13 12.1 0.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) RSS_P20 PF11757.3 EME32246.1 - 0.12 12.4 0.1 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Fer2 PF00111.22 EME32247.1 - 1.8e-07 30.8 1.8 1.8e-07 30.8 1.3 2.3 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.19 EME32248.1 - 1.6e-29 102.8 30.0 9.4e-16 57.4 6.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME32248.1 - 1e-10 40.9 38.1 1.7e-05 23.7 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME32248.1 - 3.8e-07 28.8 0.9 3.8e-07 28.8 0.6 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein DUF2721 PF11026.3 EME32248.1 - 0.027 14.0 0.9 1.7 8.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) TEX12 PF15219.1 EME32248.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Testis-expressed 12 VRR_NUC PF08774.6 EME32249.1 - 2.2e-12 46.8 0.0 6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Sgf11 PF08209.6 EME32249.1 - 2.1e-07 30.1 0.2 5.4e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) UCH PF00443.24 EME32251.1 - 0.015 14.4 0.6 0.021 13.9 0.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase NTP_transf_2 PF01909.18 EME32252.1 - 1.5e-09 38.0 0.7 4.3e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain LNS2 PF08235.8 EME32253.1 - 6e-63 211.1 0.0 1.4e-62 209.8 0.0 1.7 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EME32253.1 - 1.8e-25 88.7 0.0 5.8e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region HAD PF12710.2 EME32253.1 - 0.026 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Actin PF00022.14 EME32254.1 - 3.4e-90 302.3 0.0 3.9e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME32254.1 - 5e-06 25.3 0.0 0.021 13.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Glyco_hydro_15 PF00723.16 EME32255.1 - 8.3e-05 21.3 0.2 0.01 14.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_transf_36 PF06165.6 EME32255.1 - 0.0065 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 36 PP2C PF00481.16 EME32256.1 - 3.6e-44 151.0 0.0 3.1e-42 144.7 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME32256.1 - 7.6e-07 28.7 0.3 4.1e-06 26.3 0.2 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.26 EME32257.1 - 2.4e-15 56.3 0.1 4.6e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32257.1 - 0.00067 19.7 3.6 0.0012 18.8 0.6 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain RNA_pol_Rpb4 PF03874.11 EME32257.1 - 0.15 12.0 1.6 0.2 11.6 0.3 2.1 1 1 0 1 1 1 0 RNA polymerase Rpb4 DUF4164 PF13747.1 EME32257.1 - 2.9 8.0 6.5 8.1 6.6 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) TPR_12 PF13424.1 EME32258.1 - 3.4e-09 36.5 1.4 0.00051 19.9 0.1 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME32258.1 - 1e-05 25.0 1.4 0.032 13.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EME32258.1 - 0.00055 19.6 0.2 1.7 8.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME32258.1 - 0.037 13.6 0.1 6.3 6.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME32258.1 - 0.16 11.9 3.7 2.5 8.1 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME32258.1 - 3.8 7.5 5.1 26 4.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Abi PF02517.11 EME32259.1 - 7.5e-18 64.4 6.1 7.5e-18 64.4 4.2 2.4 3 0 0 3 3 3 1 CAAX protease self-immunity Phosphoesterase PF04185.9 EME32260.1 - 1.8e-22 80.0 4.2 5.5e-16 58.7 1.0 2.0 2 0 0 2 2 2 2 Phosphoesterase family Rieske PF00355.21 EME32261.1 - 4.4e-16 58.2 0.7 8.5e-16 57.3 0.5 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.5 EME32261.1 - 4.6e-09 36.1 0.8 7.3e-09 35.4 0.5 1.3 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit FAM74 PF15026.1 EME32262.1 - 0.053 13.1 3.6 4.6 6.8 0.0 2.4 2 1 0 2 2 2 0 FAM74 protein DUF445 PF04286.7 EME32262.1 - 0.33 10.4 9.9 0.48 9.8 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Asp-B-Hydro_N PF05279.6 EME32262.1 - 0.83 9.4 9.9 1.2 8.8 6.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TBPIP PF07106.8 EME32262.1 - 1.1 8.8 14.3 1.4 8.4 9.1 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF87 PF01935.12 EME32262.1 - 2.4 7.9 8.7 0.52 10.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 DUF3573 PF12097.3 EME32262.1 - 3.8 6.0 10.6 1.5 7.3 5.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) APH PF01636.18 EME32263.1 - 8.6e-45 153.3 0.0 5.6e-43 147.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 EME32263.1 - 5.1e-35 120.7 3.8 8.9e-35 119.9 2.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME32263.1 - 1.6e-13 51.1 0.0 4.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME32263.1 - 2e-13 50.7 1.3 3.3e-13 50.0 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME32263.1 - 2e-12 46.4 0.0 3.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain EcKinase PF02958.15 EME32263.1 - 3.2e-05 23.2 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EME32263.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EME32263.1 - 0.061 12.6 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.6 EME32263.1 - 0.16 10.5 0.0 0.71 8.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) HALZ PF02183.13 EME32264.1 - 0.00019 21.0 1.2 0.0009 18.9 0.2 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EME32264.1 - 0.011 14.8 1.3 0.02 14.1 0.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Hemerythrin PF01814.18 EME32264.1 - 0.31 11.2 4.9 1 9.4 0.6 2.9 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain TLE_N PF03920.10 EME32264.1 - 0.41 10.4 7.4 0.15 11.8 3.2 1.7 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Baculo_PEP_C PF04513.7 EME32264.1 - 0.91 9.3 5.2 0.91 9.3 1.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EME32264.1 - 1.1 9.0 14.4 0.26 11.0 3.8 2.4 1 1 1 2 2 2 0 Laminin Domain II Cep57_CLD_2 PF14197.1 EME32264.1 - 3.4 7.6 14.2 0.07 13.0 3.5 2.9 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF4200 PF13863.1 EME32264.1 - 5.1 7.0 26.9 2.1 8.3 4.5 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) EAP30 PF04157.11 EME32264.1 - 6.5 5.8 11.8 0.52 9.4 3.0 2.3 1 1 1 2 2 2 0 EAP30/Vps36 family BLOC1_2 PF10046.4 EME32264.1 - 6.6 6.9 13.2 3.9 7.6 2.6 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AhpC-TSA PF00578.16 EME32265.1 - 2.4e-37 127.3 0.0 3.7e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME32265.1 - 6.6e-25 87.3 0.0 9.2e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EME32265.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF2423 PF10338.4 EME32266.1 - 0.028 14.3 0.3 0.093 12.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Mito_fiss_reg PF05308.6 EME32266.1 - 2.7 7.2 14.9 99 2.1 10.3 2.4 1 1 0 1 1 1 0 Mitochondrial fission regulator SMN PF06003.7 EME32266.1 - 5.9 5.9 10.7 0.15 11.1 3.1 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) bZIP_1 PF00170.16 EME32267.1 - 0.00041 20.2 16.5 0.004 17.0 11.5 2.0 1 1 0 1 1 1 1 bZIP transcription factor MAP7 PF05672.6 EME32267.1 - 0.023 14.0 6.1 0.024 14.0 4.2 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF724 PF05266.9 EME32267.1 - 0.046 13.3 4.4 0.051 13.2 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Porphobil_deam PF01379.15 EME32267.1 - 0.049 12.5 0.2 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain ATG16 PF08614.6 EME32267.1 - 0.16 11.7 6.0 0.18 11.5 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Siah-Interact_N PF09032.6 EME32267.1 - 0.18 11.8 5.6 0.32 11.0 3.8 1.7 1 1 0 1 1 1 0 Siah interacting protein, N terminal APG6 PF04111.7 EME32267.1 - 0.23 10.4 5.7 0.22 10.5 3.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EME32267.1 - 5.3 6.9 18.2 1e+02 2.8 12.0 2.8 1 1 1 2 2 2 0 Basic region leucine zipper WD40 PF00400.27 EME32268.1 - 9.8e-28 95.0 1.9 8e-06 25.5 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EME32268.1 - 0.00054 19.7 0.1 2.3 7.9 0.0 3.6 1 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME32268.1 - 0.052 11.6 0.0 5.3 5.0 0.0 2.6 1 1 0 3 3 3 0 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 EME32269.1 - 7.4e-14 52.1 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME32269.1 - 5.7e-07 29.3 0.0 1.8e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold CUE PF02845.11 EME32269.1 - 0.00017 20.9 0.1 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 CUE domain Abhydrolase_5 PF12695.2 EME32269.1 - 0.00026 20.7 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EME32269.1 - 0.0023 16.4 0.0 0.0038 15.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family FKBP_C PF00254.23 EME32270.1 - 3e-18 65.6 0.0 9.8e-18 63.9 0.0 1.8 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.23 EME32271.1 - 6.2e-18 64.6 0.0 1.8e-17 63.0 0.0 1.8 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Uso1_p115_head PF04869.9 EME32272.1 - 1.9e-19 69.6 7.6 2.3e-19 69.3 0.4 3.2 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Arm PF00514.18 EME32272.1 - 0.001 18.8 0.3 26 4.8 0.0 5.0 3 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EME32272.1 - 0.034 14.2 5.0 4.3 7.6 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat RIX1 PF08167.7 EME32272.1 - 0.62 9.7 8.4 0.29 10.7 0.1 3.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis EamA PF00892.15 EME32273.1 - 9.3e-15 54.7 32.9 5.3e-08 32.9 7.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EME32273.1 - 3.3e-13 49.5 11.0 3.3e-13 49.5 7.6 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME32273.1 - 8.8e-13 47.8 23.6 1.1e-12 47.5 16.3 1.1 1 0 0 1 1 1 1 UAA transporter family ETF PF01012.16 EME32274.1 - 2.9e-38 131.1 0.1 4.1e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SET PF00856.23 EME32276.1 - 2.1e-15 57.3 0.2 1.3e-14 54.8 0.0 2.4 2 1 0 2 2 2 1 SET domain Mo25 PF08569.6 EME32276.1 - 0.0051 15.8 1.1 0.013 14.6 0.5 1.8 2 0 0 2 2 2 1 Mo25-like FKBP_C PF00254.23 EME32278.1 - 6.6e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4606 PF15379.1 EME32278.1 - 0.93 9.5 5.7 1.2 9.1 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) Nramp PF01566.13 EME32279.1 - 1.7e-91 306.7 20.7 1.7e-91 306.7 14.4 1.7 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein PPR PF01535.15 EME32280.1 - 3.4e-08 32.9 4.9 1.5 8.9 0.0 6.5 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.1 EME32280.1 - 9.6e-06 25.4 0.1 0.088 12.7 0.0 5.3 5 0 0 5 5 5 1 PPR repeat family MRP-S27 PF10037.4 EME32280.1 - 0.004 16.1 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.1 EME32280.1 - 0.26 12.0 2.6 3.8 8.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_5 PF13854.1 EME32281.1 - 1.4e-37 127.0 5.0 1.1e-06 28.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EME32281.1 - 3.9e-34 116.0 2.3 2.8e-10 40.0 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EME32281.1 - 3.5e-33 113.1 8.1 2.2e-09 36.9 0.0 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EME32281.1 - 2.4e-30 103.7 15.0 1.4e-08 34.1 0.0 6.5 8 0 0 8 8 8 5 Kelch motif Kelch_6 PF13964.1 EME32281.1 - 3.2e-28 96.7 4.9 6.6e-07 29.2 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EME32281.1 - 1.1e-23 81.9 11.4 4e-05 23.1 0.0 6.3 6 0 0 6 6 6 5 Kelch motif BTB PF00651.26 EME32281.1 - 2.4e-21 75.8 0.4 9.3e-20 70.6 0.1 2.8 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 EME32281.1 - 0.0002 21.1 0.1 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch RAG2 PF03089.9 EME32281.1 - 0.0016 17.2 0.3 3.9 6.0 0.1 3.6 2 1 1 3 3 3 2 Recombination activating protein 2 Thioredoxin PF00085.15 EME32282.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Birna_RdRp PF04197.7 EME32282.1 - 0.084 10.9 0.1 0.11 10.5 0.1 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF1640 PF07798.6 EME32283.1 - 1.1e-09 38.5 3.5 3.6e-07 30.4 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) DUF3508 PF12018.3 EME32283.1 - 0.013 14.5 1.6 0.019 13.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF2228 PF10228.4 EME32283.1 - 0.092 12.2 1.0 0.14 11.7 0.7 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DAP_epimerase PF01678.14 EME32284.1 - 1.4e-59 199.2 0.0 1.6e-29 102.2 0.0 2.3 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.11 EME32284.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EME32284.1 - 0.077 11.8 0.0 0.24 10.1 0.0 1.8 2 1 0 2 2 2 0 Proline racemase DEAD PF00270.24 EME32285.1 - 4.7e-17 61.9 0.0 9.1e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME32285.1 - 1.6e-15 56.6 0.0 3.5e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME32285.1 - 0.00031 20.6 0.0 0.0032 17.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME32285.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_L23eN PF03939.8 EME32286.1 - 3.5e-18 65.3 14.3 3.5e-18 65.3 9.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EME32286.1 - 4.6e-17 61.7 0.8 4.6e-17 61.7 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 EME32286.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Ribosomal_S5_C PF03719.10 EME32287.1 - 2.3e-18 65.2 0.1 4.2e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EME32287.1 - 1e-14 53.9 0.0 1.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Fis1_TPR_C PF14853.1 EME32288.1 - 8.7e-12 44.7 0.3 3.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EME32288.1 - 9.7e-07 27.9 0.0 1.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.1 EME32288.1 - 5.5e-05 23.3 0.1 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CPSF_A PF03178.10 EME32288.1 - 0.031 13.3 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 CPSF A subunit region TPR_2 PF07719.12 EME32288.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PetG PF02529.10 EME32288.1 - 0.064 12.7 3.6 2.6 7.6 1.5 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 YfiO PF13525.1 EME32288.1 - 0.1 12.0 0.2 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_14 PF13428.1 EME32288.1 - 0.11 13.2 0.0 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PEX11 PF05648.9 EME32289.1 - 0.83 8.8 8.4 1.2 8.3 5.8 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) CAF-1_p150 PF11600.3 EME32289.1 - 1.2 8.5 34.2 1.2 8.4 23.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4337 PF14235.1 EME32289.1 - 5.6 6.7 10.9 6.7 6.5 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spore_coat_CotO PF14153.1 EME32289.1 - 6.7 6.1 14.2 8 5.8 9.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO NDUF_B5 PF09781.4 EME32289.1 - 7.9 5.7 7.6 8.3 5.6 5.3 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit E2F_TDP PF02319.15 EME32292.1 - 2.4e-15 55.8 0.4 4e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DUF3853 PF12964.2 EME32292.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) AhpC-TSA PF00578.16 EME32294.1 - 1.8e-16 59.9 0.0 2.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME32294.1 - 3.2e-09 36.4 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EME32294.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME32294.1 - 0.0023 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EME32295.1 - 1.8e-16 59.9 0.0 2.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME32295.1 - 3.2e-09 36.4 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EME32295.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME32295.1 - 0.0023 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Acylphosphatase PF00708.13 EME32296.1 - 1.6e-23 82.6 0.0 1.7e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase Spheroidin PF05541.7 EME32296.1 - 0.068 10.7 0.0 0.071 10.7 0.0 1.0 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Sugar_tr PF00083.19 EME32297.1 - 8.1e-23 80.6 18.5 2.4e-15 56.0 6.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME32297.1 - 9.3e-10 37.7 24.8 4.7e-08 32.1 9.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1654 PF07867.6 EME32298.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) FMN_red PF03358.10 EME32300.1 - 7.6e-23 80.6 0.0 1.1e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase MFS_1 PF07690.11 EME32301.1 - 1.4e-41 142.4 64.9 3.9e-35 121.2 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EME32301.1 - 2e-09 36.0 0.2 4.5e-09 34.9 0.2 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.14 EME32301.1 - 0.00017 20.2 11.1 0.00017 20.2 7.7 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter MtrF PF09472.5 EME32301.1 - 10 5.4 6.6 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) L51_S25_CI-B8 PF05047.11 EME32302.1 - 3.8e-07 29.7 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain UbiA PF01040.13 EME32303.1 - 9.5e-32 110.2 13.8 1.1e-31 109.9 9.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Beach PF02138.13 EME32304.1 - 1.5e-102 342.6 0.0 3e-102 341.7 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EME32304.1 - 1.1e-15 57.3 0.3 1.1e-15 57.3 0.2 3.2 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EME32304.1 - 2.7e-10 39.7 3.0 7.8e-08 31.9 0.3 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EME32304.1 - 1.1e-06 28.9 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PseudoU_synth_2 PF00849.17 EME32305.1 - 1.1e-32 113.1 1.2 1.7e-32 112.5 0.8 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DEAD PF00270.24 EME32306.1 - 1.2e-25 89.9 0.0 8.8e-24 83.8 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME32306.1 - 2.2e-18 65.8 0.5 4.8e-18 64.7 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME32306.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME32306.1 - 0.0014 18.7 1.2 0.3 11.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain SNF2_N PF00176.18 EME32306.1 - 0.014 14.1 0.0 0.26 10.0 0.0 2.6 2 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_19 PF13245.1 EME32306.1 - 0.094 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ALMT PF11744.3 EME32307.1 - 7.6e-08 31.4 9.4 4.1e-05 22.4 0.8 2.5 1 1 1 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EME32307.1 - 0.16 11.9 38.7 1.4 8.8 10.0 2.5 2 0 0 2 2 2 0 Fusaric acid resistance protein-like PRESAN PF09687.5 EME32307.1 - 0.19 11.8 3.3 0.37 10.8 0.1 2.6 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Mago_nashi PF02792.9 EME32308.1 - 1e-81 271.6 0.7 1.2e-81 271.4 0.5 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 EME32308.1 - 0.097 12.4 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) START PF01852.14 EME32309.1 - 0.012 14.8 0.0 0.035 13.4 0.0 1.7 1 1 0 1 1 1 0 START domain DUF4363 PF14276.1 EME32309.1 - 0.014 15.0 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Aldose_epim PF01263.15 EME32310.1 - 2.4e-69 233.7 0.7 2.9e-69 233.4 0.5 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase FrpC PF06901.7 EME32310.1 - 0.0053 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 RTX iron-regulated protein FrpC AMP-binding PF00501.23 EME32311.1 - 2.4e-10 39.4 0.0 3.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 EME32313.1 - 2e-18 65.5 10.6 5.5e-07 29.2 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.7 EME32313.1 - 0.0098 15.5 0.0 4.5 7.0 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat MCM PF00493.18 EME32314.1 - 1.1e-138 461.5 0.0 1.7e-138 460.9 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME32314.1 - 2.5e-19 69.9 0.2 1.2e-18 67.7 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 EME32314.1 - 2.3e-11 43.9 22.1 2.3e-11 43.9 15.3 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 EME32314.1 - 1.1e-08 34.4 0.0 4.8e-07 29.1 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME32314.1 - 2.6e-06 27.1 0.0 5.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME32314.1 - 0.00029 20.4 0.0 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME32314.1 - 0.028 13.9 0.1 0.6 9.5 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EME32314.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G6PD_C PF02781.11 EME32315.1 - 3.2e-94 315.0 0.0 4.8e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EME32315.1 - 2.3e-60 203.9 0.0 3.7e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Polyketide_cyc PF03364.15 EME32316.1 - 1.1e-11 44.8 0.0 2.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EME32316.1 - 7.2e-08 32.6 0.0 9.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.8 EME32316.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Utp11 PF03998.8 EME32317.1 - 3.1e-47 161.4 7.6 4.2e-47 161.0 5.3 1.2 1 0 0 1 1 1 1 Utp11 protein MerR-DNA-bind PF09278.6 EME32317.1 - 0.0032 17.8 2.7 0.038 14.3 0.0 2.9 3 0 0 3 3 3 1 MerR, DNA binding DUF2408 PF10303.4 EME32317.1 - 0.06 13.4 4.3 2.4 8.3 3.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Exostosin PF03016.10 EME32318.1 - 3.9e-24 85.2 0.0 3.2e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Exostosin family Metalloenzyme PF01676.13 EME32319.1 - 8.8e-60 202.1 0.0 1.1e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EME32319.1 - 6.1e-55 185.9 0.0 9.1e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EME32319.1 - 0.00019 20.8 0.0 0.0007 19.0 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_14 PF01373.12 EME32320.1 - 4.4e-100 335.2 0.3 5.5e-100 334.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_14 PF01373.12 EME32321.1 - 4.4e-100 335.2 0.3 5.5e-100 334.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Polysacc_deac_1 PF01522.16 EME32322.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase ALMT PF11744.3 EME32323.1 - 0.00084 18.0 9.4 0.00084 18.0 6.5 2.5 2 1 0 2 2 2 1 Aluminium activated malate transporter DUF2421 PF10334.4 EME32323.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EME32323.1 - 0.044 12.2 34.1 0.036 12.5 7.5 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family FUSC_2 PF13515.1 EME32323.1 - 0.16 11.8 43.1 0.027 14.4 13.5 3.2 2 2 1 3 3 3 0 Fusaric acid resistance protein-like Y_phosphatase PF00102.22 EME32323.1 - 0.21 10.8 0.2 19 4.5 0.0 2.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase EPSP_synthase PF00275.15 EME32324.1 - 3.7e-136 453.8 0.0 4.3e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) KaiC PF06745.8 EME32325.1 - 2.5e-09 36.6 0.0 6.3e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EME32325.1 - 2.7e-06 26.9 0.0 6.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME32325.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME32325.1 - 0.0015 17.7 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME32325.1 - 0.0025 17.8 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EME32325.1 - 0.019 13.9 0.0 0.064 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EME32325.1 - 0.019 15.2 0.0 0.36 11.1 0.0 2.7 2 1 0 2 2 2 0 ABC transporter DUF1088 PF06469.6 EME32325.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) PRK PF00485.13 EME32325.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 EME32325.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EME32325.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATP-synt_ab PF00006.20 EME32326.1 - 2.7e-69 232.9 0.0 4.1e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME32326.1 - 1.4e-26 93.1 0.7 2.9e-26 92.1 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME32326.1 - 6.3e-19 67.9 5.0 1.2e-18 67.0 2.9 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EME32326.1 - 2.8e-07 30.3 2.6 6.4e-07 29.1 1.8 1.7 1 0 0 1 1 1 1 HAS barrel domain DUF3725 PF12523.3 EME32326.1 - 0.064 13.3 0.1 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) TruD PF01142.13 EME32327.1 - 6.5e-61 206.0 0.3 1.4e-58 198.3 0.0 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) R3H PF01424.17 EME32327.1 - 0.0013 18.3 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain NTF2 PF02136.15 EME32328.1 - 3.1e-33 114.6 0.1 3.7e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lectin_C PF00059.16 EME32328.1 - 0.16 12.6 0.6 1.8 9.2 0.2 2.1 2 0 0 2 2 2 0 Lectin C-type domain Sugar_tr PF00083.19 EME32329.1 - 5.7e-82 275.6 19.9 1.1e-81 274.7 13.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME32329.1 - 1.3e-25 89.8 31.7 1.3e-25 89.8 22.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME32329.1 - 0.00049 18.6 3.9 0.00049 18.6 2.7 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 EME32329.1 - 2.7 5.9 9.0 2.9 5.9 0.8 2.9 3 0 0 3 3 3 0 Transmembrane secretion effector DEAD PF00270.24 EME32330.1 - 2.2e-40 137.9 0.0 3.6e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME32330.1 - 2.8e-21 75.1 0.0 1.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EME32330.1 - 0.00047 19.3 0.0 0.00091 18.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EME32330.1 - 0.0052 16.6 0.0 0.025 14.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EME32330.1 - 0.079 12.2 0.2 0.37 10.0 0.1 2.1 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain VSG_B PF13206.1 EME32331.1 - 0.071 12.2 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Cytomega_TRL10 PF06084.6 EME32331.1 - 0.15 11.8 1.1 4 7.2 0.0 2.0 1 1 1 2 2 2 0 Cytomegalovirus TRL10 protein zf-AN1 PF01428.11 EME32332.1 - 2.2e-12 46.6 9.3 2.2e-12 46.6 6.4 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EME32332.1 - 1.7e-09 37.1 5.7 1.7e-09 37.1 3.9 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-C5HC2 PF02928.11 EME32332.1 - 3 7.9 9.8 0.56 10.3 3.9 1.9 2 0 0 2 2 2 0 C5HC2 zinc finger MitMem_reg PF13012.1 EME32333.1 - 3e-30 104.6 0.1 5.6e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EME32333.1 - 1.6e-24 85.8 0.0 3.3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Clat_adaptor_s PF01217.15 EME32333.1 - 0.12 12.1 0.4 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Clathrin adaptor complex small chain bZIP_1 PF00170.16 EME32334.1 - 5.9e-08 32.5 10.0 1.4e-07 31.3 7.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME32334.1 - 6.9e-07 28.9 8.9 1.8e-06 27.6 6.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper CAF-1_p150 PF11600.3 EME32334.1 - 0.032 13.5 17.2 0.056 12.8 11.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2205 PF10224.4 EME32334.1 - 0.67 9.5 8.8 0.58 9.7 3.8 2.5 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) G_glu_transpept PF01019.16 EME32335.1 - 4.6e-137 457.5 0.0 5.5e-99 331.9 0.0 2.1 1 1 0 2 2 2 2 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.16 EME32336.1 - 6.4e-137 457.1 0.0 6.7e-99 331.6 0.0 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase PepSY_TM_1 PF13172.1 EME32336.1 - 8.1 6.3 7.6 4.9 7.0 0.1 2.8 3 0 0 3 3 3 0 PepSY-associated TM helix Profilin PF00235.14 EME32337.1 - 1e-26 93.4 0.0 1.2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Profilin CLTH PF10607.4 EME32338.1 - 5.5e-15 55.3 0.0 8.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EME32338.1 - 0.022 14.5 0.1 0.067 12.9 0.1 1.8 1 0 0 1 1 1 0 LisH Glyco_hydro_31 PF01055.21 EME32339.1 - 3.8e-58 197.3 0.2 4.4e-58 197.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 EME32340.1 - 3.5e-25 88.7 0.0 5.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME32340.1 - 3.8e-12 45.8 0.0 7.5e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_S9 PF00326.16 EME32341.1 - 2.8e-14 52.8 0.0 8.3e-14 51.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EME32341.1 - 0.00026 19.6 1.5 0.0012 17.4 1.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 EME32341.1 - 0.0037 17.1 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME32341.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NUMOD3 PF07460.6 EME32342.1 - 1.7e-05 24.6 7.4 0.016 15.0 0.7 3.7 2 1 1 3 3 3 2 NUMOD3 motif (2 copies) UL11 PF11094.3 EME32342.1 - 0.012 15.4 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_L5 PF04872.8 EME32342.1 - 0.04 13.5 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Poxvirus L5 protein family DEAD PF00270.24 EME32343.1 - 3.4e-40 137.3 0.7 1.4e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME32343.1 - 2.6e-28 97.7 0.3 9.6e-28 95.8 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EME32343.1 - 0.0026 17.4 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain CMS1 PF14617.1 EME32343.1 - 0.0029 16.7 0.0 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EME32343.1 - 0.0029 17.3 0.1 0.0085 15.8 0.0 1.8 1 1 0 1 1 1 1 Flavivirus DEAD domain DUF1253 PF06862.7 EME32343.1 - 0.0037 15.7 0.4 0.51 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) tRNA-synt_1b PF00579.20 EME32343.1 - 0.02 14.0 0.0 0.077 12.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) VCBS PF13517.1 EME32344.1 - 4.4e-21 74.9 19.4 5.6e-08 33.0 2.2 5.3 3 1 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EME32344.1 - 3.1e-14 52.1 21.7 0.0055 16.3 0.1 6.6 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EME32344.1 - 4.5e-07 29.4 9.8 0.49 9.8 0.0 6.9 4 1 4 8 8 8 3 Insecticide toxin TcdB middle/N-terminal region Sec1 PF00995.18 EME32345.1 - 6.8e-65 219.7 0.0 8.7e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Aconitase PF00330.15 EME32346.1 - 8.5e-71 238.8 0.0 1.8e-48 165.1 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) VMA21 PF09446.5 EME32346.1 - 4.8e-06 26.3 1.2 9.9e-06 25.3 0.8 1.5 1 0 0 1 1 1 1 VMA21-like domain Pro_isomerase PF00160.16 EME32348.1 - 1.6e-47 161.6 0.0 2.4e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PI3_PI4_kinase PF00454.22 EME32349.1 - 5.6e-60 202.7 0.4 1.2e-59 201.6 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EME32349.1 - 1.2e-59 202.0 9.7 3.4e-59 200.6 6.7 1.9 1 0 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 EME32349.1 - 4.1e-41 139.1 2.6 6.1e-41 138.5 0.3 2.7 2 0 0 2 2 2 1 Rapamycin binding domain DUF3385 PF11865.3 EME32349.1 - 2e-25 89.5 0.3 4.3e-12 46.2 0.0 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) FATC PF02260.15 EME32349.1 - 3.1e-14 52.0 0.7 9.8e-14 50.5 0.5 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EME32349.1 - 1.1e-06 28.7 26.5 0.042 14.1 0.3 8.4 11 1 0 11 11 11 4 HEAT repeats HEAT PF02985.17 EME32349.1 - 8e-05 22.3 15.5 1.5 9.1 0.0 9.2 9 0 0 9 9 9 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EME32349.1 - 0.0019 18.5 0.7 22 5.4 0.0 6.0 7 0 0 7 7 7 0 Vacuolar 14 Fab1-binding region PfkB PF00294.19 EME32350.1 - 5.8e-29 101.1 0.0 1.4e-28 99.9 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF2140 PF09911.4 EME32351.1 - 0.17 11.0 1.8 0.19 10.8 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) BLVR PF06375.6 EME32351.1 - 2.3 8.0 7.0 2.6 7.8 4.9 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SARS_X4 PF08779.5 EME32352.1 - 0.071 13.2 0.8 0.34 11.0 0.0 2.4 2 1 0 2 2 2 0 SARS coronavirus X4 like FAD-oxidase_C PF02913.14 EME32353.1 - 2.8e-57 193.9 0.0 4.2e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EME32353.1 - 2.3e-35 121.0 0.1 5.5e-35 119.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pro_isomerase PF00160.16 EME32354.1 - 4.2e-36 124.4 0.0 7.4e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Menin PF05053.8 EME32354.1 - 0.042 12.0 4.6 0.05 11.7 3.2 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.2 EME32354.1 - 0.24 9.0 7.0 0.3 8.7 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF566 PF04484.7 EME32354.1 - 3.8 6.9 17.8 5 6.5 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1744 PF08490.7 EME32355.1 - 4.7e-59 199.9 2.1 4.7e-59 199.9 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EME32355.1 - 2.6e-49 167.8 0.3 6.1e-49 166.6 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EME32355.1 - 2e-22 79.6 0.7 5.9e-21 74.7 0.3 2.5 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EME32355.1 - 3e-08 33.4 0.0 1.1e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EME32355.1 - 1.3e-06 28.3 0.0 5.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily Ribosomal_S17 PF00366.15 EME32355.1 - 0.078 13.0 0.1 4 7.5 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S17 TPR_11 PF13414.1 EME32356.1 - 0.0076 15.8 1.6 0.12 12.0 0.2 3.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 EME32356.1 - 0.035 14.4 0.1 4.2 7.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME32356.1 - 1.6 8.4 9.5 0.17 11.5 0.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1640 PF07798.6 EME32357.1 - 3.4e-18 66.2 1.5 1.1e-09 38.6 0.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) DUF4618 PF15397.1 EME32357.1 - 0.0019 17.5 0.3 0.0023 17.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Aminotran_1_2 PF00155.16 EME32358.1 - 1.8e-62 211.4 0.0 2.1e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME32358.1 - 2.6e-06 26.7 0.0 9.5e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EME32358.1 - 0.00026 19.3 0.0 0.0004 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME32358.1 - 0.0022 17.1 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EME32358.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF179 PF02622.10 EME32359.1 - 5.4e-22 78.1 0.0 9.3e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ish1 PF10281.4 EME32359.1 - 0.019 15.0 1.5 0.037 14.1 1.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Complex1_LYR PF05347.10 EME32359.1 - 0.034 13.9 1.5 0.6 9.9 0.3 2.4 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME32359.1 - 0.039 14.1 0.5 0.094 12.9 0.1 2.0 2 0 0 2 2 2 0 Complex1_LYR-like Herpes_ICP4_N PF03584.10 EME32361.1 - 0.2 11.1 0.0 0.2 11.1 0.0 3.7 4 0 0 4 4 4 0 Herpesvirus ICP4-like protein N-terminal region RolB_RolC PF02027.12 EME32361.1 - 0.34 10.0 7.4 0.15 11.2 1.5 2.5 1 1 1 2 2 2 0 RolB/RolC glucosidase family EAF PF09816.4 EME32362.1 - 1.9e-05 24.5 0.0 0.0001 22.1 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase II transcription elongation factor Baculo_E56 PF04639.7 EME32362.1 - 0.086 11.4 0.1 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope EAF PF09816.4 EME32363.1 - 2.3e-05 24.2 0.0 0.00013 21.8 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase II transcription elongation factor Baculo_E56 PF04639.7 EME32363.1 - 0.097 11.3 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Na_H_Exchanger PF00999.16 EME32364.1 - 2.2e-67 227.2 47.6 3.1e-67 226.7 33.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.13 EME32364.1 - 3.6e-26 91.4 0.0 7.7e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 60KD_IMP PF02096.15 EME32365.1 - 2.7e-35 121.8 2.7 4.1e-35 121.2 1.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ATP-synt_B PF00430.13 EME32365.1 - 0.13 12.0 1.0 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Ank PF00023.25 EME32366.1 - 4e-41 136.8 2.6 3.7e-10 39.0 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EME32366.1 - 4.6e-40 135.8 0.5 5.9e-20 71.4 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME32366.1 - 6.9e-39 131.5 5.2 2.1e-13 50.3 0.0 5.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME32366.1 - 1.8e-34 116.9 1.1 4.2e-11 42.7 0.2 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME32366.1 - 1.4e-31 105.3 0.6 1.1e-07 31.3 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Acyltransferase PF01553.16 EME32367.1 - 7.7e-15 54.4 0.0 1.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TrfA PF07042.6 EME32368.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 TrfA protein Atg14 PF10186.4 EME32368.1 - 0.02 13.8 15.5 0.054 12.4 6.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaphilin PF15290.1 EME32368.1 - 0.065 12.7 15.1 0.014 14.9 6.5 2.0 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Matrilin_ccoil PF10393.4 EME32368.1 - 0.87 8.9 8.4 0.53 9.6 0.2 3.3 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Toxin_39 PF15500.1 EME32368.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Putative RNase-like toxin DASH_Dad3 PF08656.5 EME32368.1 - 1.8 8.3 11.7 2.6 7.7 1.7 3.4 3 1 0 3 3 3 0 DASH complex subunit Dad3 TPD52 PF04201.10 EME32368.1 - 1.9 8.1 11.3 0.5 10.0 4.4 2.3 2 1 0 2 2 2 0 Tumour protein D52 family APG6 PF04111.7 EME32368.1 - 5 6.0 20.8 0.63 9.0 9.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 EME32368.1 - 6.1 6.9 25.2 6.3 6.9 9.6 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Microtub_bind PF13931.1 EME32368.1 - 6.6 6.8 14.0 1.6 8.8 6.2 2.3 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Pyr_redox_2 PF07992.9 EME32369.1 - 2.9e-26 92.5 1.6 2.5e-25 89.5 1.1 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME32369.1 - 4.6e-17 62.1 4.1 1e-14 54.6 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME32369.1 - 4.8e-11 43.1 0.2 7.8e-07 29.3 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EME32369.1 - 0.00039 20.6 0.0 0.031 14.5 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 EME32369.1 - 0.0059 15.2 1.9 0.15 10.6 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.19 EME32369.1 - 0.0064 15.4 9.3 0.25 10.1 0.0 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EME32369.1 - 0.018 15.1 3.4 0.27 11.3 0.1 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase RE_Alw26IDE PF09665.5 EME32369.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) K_oxygenase PF13434.1 EME32369.1 - 0.26 10.1 1.2 0.7 8.7 0.2 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME32369.1 - 1.7 8.4 5.9 9.1 6.0 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.17 EME32369.1 - 3.4 6.4 12.4 0.58 8.9 0.2 3.3 3 1 0 4 4 4 0 Glucose inhibited division protein A NPR2 PF06218.6 EME32370.1 - 2.1e-38 132.1 0.6 3e-38 131.6 0.4 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 WD40 PF00400.27 EME32371.1 - 1e-07 31.5 10.9 0.65 9.9 0.1 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EME32371.1 - 0.00023 20.9 0.0 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EME32371.1 - 0.0009 17.1 1.5 0.12 10.1 0.0 3.0 1 1 2 3 3 3 2 IKI3 family ATC_hydrolase PF14196.1 EME32372.1 - 2.2e-05 24.8 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF3969 PF13108.1 EME32372.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) ATC_hydrolase PF14196.1 EME32373.1 - 1.5e-08 35.2 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF3969 PF13108.1 EME32373.1 - 0.086 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Pkinase PF00069.20 EME32374.1 - 1.6e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32374.1 - 0.044 12.8 0.0 0.087 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Gp_dh_C PF02800.15 EME32375.1 - 8.6e-71 236.4 0.0 1.2e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EME32375.1 - 3.1e-60 202.5 0.2 6.9e-60 201.3 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EME32375.1 - 0.014 15.2 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EME32375.1 - 0.099 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIS PF01380.17 EME32376.1 - 2.2e-56 189.0 0.2 3.5e-29 101.0 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EME32376.1 - 1.4e-25 89.7 0.2 1.8e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME32376.1 - 2.2e-18 66.4 0.0 1.8e-17 63.5 0.0 2.2 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EME32376.1 - 3.4e-13 49.4 0.0 1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EME32376.1 - 9.2e-08 31.0 0.0 2.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EME32376.1 - 2.2e-05 24.1 0.1 0.0075 15.9 0.0 2.8 2 1 0 3 3 3 2 SIS domain SIS PF01380.17 EME32377.1 - 2e-56 189.2 0.5 3.6e-29 100.9 0.1 2.7 3 0 0 3 3 3 2 SIS domain GATase_2 PF00310.16 EME32377.1 - 2e-19 69.5 0.2 1.8e-16 59.7 0.0 3.1 3 0 0 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME32377.1 - 2.4e-18 66.3 0.0 1.8e-17 63.5 0.0 2.1 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EME32377.1 - 3.6e-13 49.3 0.0 1.1e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EME32377.1 - 9.6e-08 31.0 0.0 2.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EME32377.1 - 2.3e-05 24.1 0.1 0.0078 15.9 0.0 2.8 2 1 0 3 3 3 2 SIS domain BolA PF01722.13 EME32378.1 - 2.2e-17 62.7 0.0 2.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein QueF PF14489.1 EME32378.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 QueF-like protein Topoisom_bac PF01131.15 EME32378.1 - 0.1 11.4 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 DNA topoisomerase Bromodomain PF00439.20 EME32379.1 - 2.5e-21 75.3 0.0 6.9e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain GATA PF00320.22 EME32379.1 - 3.9e-14 51.6 3.5 1e-13 50.3 2.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Glyco_tran_28_C PF04101.11 EME32380.1 - 1.6e-08 34.4 0.0 3.2e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EME32380.1 - 4.1e-07 29.5 0.0 6.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 MGDG_synth PF06925.6 EME32380.1 - 0.00022 21.1 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase 3-alpha PF03475.9 EME32380.1 - 0.04 13.6 0.6 1.2 8.8 0.1 2.7 2 0 0 2 2 2 0 3-alpha domain DUF148 PF02520.12 EME32380.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 SNase PF00565.12 EME32381.1 - 4e-13 49.5 0.0 5.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TrmE_N PF10396.4 EME32382.1 - 2.8e-34 117.5 0.0 5.4e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EME32382.1 - 2.1e-20 72.8 3.1 3.3e-20 72.2 0.2 2.7 3 0 0 3 3 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EME32382.1 - 3.4e-09 36.6 2.7 0.00048 20.0 0.2 2.5 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME32382.1 - 1.3e-05 24.7 0.1 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME32382.1 - 0.0001 21.5 0.3 0.035 13.3 0.0 2.5 1 1 1 2 2 2 2 Ferrous iron transport protein B AAA_17 PF13207.1 EME32382.1 - 0.00029 21.6 0.8 0.0007 20.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain ArgK PF03308.11 EME32382.1 - 0.00031 19.6 0.2 0.32 9.7 0.0 2.5 2 0 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 EME32382.1 - 0.00096 18.6 0.0 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EME32382.1 - 0.0015 18.0 0.2 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EME32382.1 - 0.0028 17.9 0.2 0.0086 16.3 0.2 1.9 2 1 0 2 2 1 1 ABC transporter Dynamin_N PF00350.18 EME32382.1 - 0.0056 16.5 0.4 0.4 10.4 0.1 2.6 1 1 1 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EME32382.1 - 0.05 13.0 0.0 0.16 11.4 0.0 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EME32382.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME32382.1 - 0.076 13.5 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EME32382.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME32382.1 - 0.14 11.6 0.1 0.47 9.8 0.1 2.0 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EME32382.1 - 0.15 11.2 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TrmE_N PF10396.4 EME32383.1 - 2.5e-34 117.6 0.0 4.6e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EME32383.1 - 2.8e-09 36.9 2.7 0.00043 20.2 0.2 2.5 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME32383.1 - 1e-05 25.0 0.1 0.001 18.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME32383.1 - 8.2e-05 21.9 0.3 0.036 13.3 0.0 2.5 1 1 0 2 2 2 2 Ferrous iron transport protein B AAA_17 PF13207.1 EME32383.1 - 0.00025 21.8 0.7 0.00059 20.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain ArgK PF03308.11 EME32383.1 - 0.00029 19.7 0.2 0.29 9.8 0.0 2.3 2 0 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 EME32383.1 - 0.0008 18.9 0.0 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EME32383.1 - 0.0012 18.2 0.2 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EME32383.1 - 0.0025 18.1 0.3 0.0079 16.4 0.3 1.9 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EME32383.1 - 0.0049 16.7 0.4 0.37 10.5 0.1 2.6 1 1 1 2 2 2 1 Dynamin family GTPase_Cys_C PF12631.2 EME32383.1 - 0.0056 17.0 2.4 0.016 15.5 0.1 2.8 3 0 0 3 3 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FtsK_SpoIIIE PF01580.13 EME32383.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EME32383.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EME32383.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EME32383.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EME32383.1 - 0.13 11.4 0.0 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF581 PF04570.9 EME32384.1 - 0.00045 19.4 1.2 0.00086 18.5 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF581) DNA_RNApol_7kD PF03604.8 EME32384.1 - 0.011 15.2 0.2 0.011 15.2 0.1 1.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-HIT PF04438.11 EME32384.1 - 0.036 13.6 1.4 0.068 12.8 1.0 1.5 1 1 0 1 1 1 0 HIT zinc finger zf-FCS PF06467.9 EME32384.1 - 0.065 12.8 2.4 0.17 11.5 1.7 1.7 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Ribosomal_L7Ae PF01248.21 EME32385.1 - 5.2e-26 89.9 0.1 6.1e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CAMSAP_CH PF11971.3 EME32385.1 - 0.11 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CAMSAP CH domain DXP_reductoisom PF02670.11 EME32385.1 - 0.13 12.8 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_transf_10 PF00852.14 EME32386.1 - 2.4e-18 65.8 0.1 4.4e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Glucokinase PF02685.11 EME32387.1 - 5.7e-92 307.8 0.0 6.9e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Glucokinase Hexokinase_1 PF00349.16 EME32387.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Hexokinase vATP-synt_AC39 PF01992.11 EME32390.1 - 3.6e-92 309.0 0.0 4e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit ADH_N PF08240.7 EME32391.1 - 1.9e-29 101.6 1.4 2.9e-29 101.0 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME32391.1 - 2.3e-28 98.3 0.3 3.6e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME32391.1 - 2.5e-08 34.8 0.8 4.1e-08 34.1 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dehydratase_MU PF02288.10 EME32391.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Dehydratase medium subunit Methyltransf_18 PF12847.2 EME32391.1 - 0.13 12.8 0.1 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ham1p_like PF01725.11 EME32392.1 - 5.1e-50 169.4 0.0 6e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RRM_1 PF00076.17 EME32394.1 - 3.3e-20 71.4 0.0 4.6e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32394.1 - 1.1e-18 66.9 0.0 1.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME32394.1 - 2.3e-10 40.1 0.0 3.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EME32394.1 - 0.026 14.9 1.1 0.035 14.5 0.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family Limkain-b1 PF11608.3 EME32394.1 - 0.079 12.7 0.1 0.44 10.3 0.1 2.0 1 1 0 1 1 1 0 Limkain b1 Aminotran_5 PF00266.14 EME32395.1 - 5.2e-42 143.8 0.0 6.7e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EME32395.1 - 0.0091 14.9 0.0 0.28 10.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Peptidase_S28 PF05577.7 EME32395.1 - 0.067 11.7 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Pyridoxal_deC PF00282.14 EME32395.1 - 0.14 10.5 0.0 0.49 8.7 0.0 1.8 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Lipoprotein_6 PF01441.14 EME32396.1 - 0.062 13.1 0.9 0.09 12.6 0.6 1.4 1 1 0 1 1 1 0 Lipoprotein SNAPc_SNAP43 PF09808.4 EME32396.1 - 0.067 12.8 0.2 0.08 12.6 0.1 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF267 PF03268.9 EME32396.1 - 0.12 11.2 0.1 0.2 10.4 0.0 1.3 1 1 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 PBP PF01161.15 EME32397.1 - 5e-15 55.6 0.0 6.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Complex1_LYR PF05347.10 EME32398.1 - 2.1e-07 30.6 0.4 3.8e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME32398.1 - 1.3e-06 28.5 0.3 1.9e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DCP1 PF06058.8 EME32399.1 - 1.4e-18 67.1 0.2 2.3e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF155 PF02582.9 EME32399.1 - 0.057 13.3 0.1 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Med18 PF09637.5 EME32400.1 - 0.00027 20.5 0.0 0.0012 18.4 0.0 1.8 1 1 1 2 2 2 1 Med18 protein Med18 PF09637.5 EME32401.1 - 0.00034 20.2 0.0 0.0018 17.8 0.0 1.8 1 1 1 2 2 2 1 Med18 protein Clathrin PF00637.15 EME32402.1 - 5.5e-13 48.7 0.0 3.2e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EME32402.1 - 0.0035 17.1 0.9 3.5 7.6 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Pet127 PF08634.5 EME32403.1 - 7.3e-74 248.3 0.1 1.2e-73 247.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 NAD_binding_2 PF03446.10 EME32404.1 - 1.4e-49 168.0 0.1 2.1e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME32404.1 - 6.8e-37 126.2 0.5 6.4e-35 119.8 0.1 2.1 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EME32404.1 - 9e-08 32.4 0.1 2.5e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME32404.1 - 7.7e-06 25.1 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EME32404.1 - 5.1e-05 22.9 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EME32404.1 - 0.00015 22.2 0.0 0.00025 21.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EME32404.1 - 0.0002 20.4 0.1 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase IlvN PF07991.7 EME32404.1 - 0.00023 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EME32404.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EME32404.1 - 0.043 14.0 0.2 0.69 10.2 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EME32404.1 - 0.05 12.9 0.0 0.15 11.4 0.0 1.8 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EME32404.1 - 0.095 12.6 0.1 0.31 10.9 0.0 1.9 3 0 0 3 3 3 0 short chain dehydrogenase ApbA PF02558.11 EME32404.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Drf_DAD PF06345.6 EME32404.1 - 0.79 9.6 3.0 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 DRF Autoregulatory Domain RNA_pol_Rpb1_5 PF04998.12 EME32405.1 - 1.5e-95 319.6 1.0 2.1e-95 319.1 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EME32405.1 - 8.2e-84 281.7 0.0 1.2e-83 281.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EME32405.1 - 1e-67 227.2 0.0 2.4e-67 226.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EME32405.1 - 3.5e-32 111.3 0.0 2e-31 108.8 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EME32405.1 - 1.8e-25 88.7 0.0 5e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 GTP_EFTU PF00009.22 EME32406.1 - 1.6e-59 200.5 0.0 3.2e-59 199.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME32406.1 - 4e-37 126.4 0.1 1.7e-36 124.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EME32406.1 - 3.4e-32 110.0 0.1 1.1e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EME32406.1 - 6.7e-26 89.9 0.4 2e-25 88.4 0.3 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME32406.1 - 1.7e-16 60.0 0.0 6.3e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME32406.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AIG1 PF04548.11 EME32406.1 - 0.059 12.4 0.0 0.18 10.9 0.0 1.7 1 0 0 1 1 1 0 AIG1 family CTD_bind PF04818.8 EME32407.1 - 4.3e-06 26.8 0.0 3.4e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase II-binding domain. VHS PF00790.14 EME32407.1 - 7e-05 22.4 2.5 7.7e-05 22.3 0.0 2.3 3 0 0 3 3 3 1 VHS domain DUF1678 PF07913.6 EME32407.1 - 0.048 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) DUF4199 PF13858.1 EME32407.1 - 0.29 11.0 1.8 0.55 10.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) zf-CCCH PF00642.19 EME32408.1 - 0.024 14.3 1.7 0.024 14.3 1.2 5.5 5 1 1 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 EME32409.1 - 0.024 14.3 1.7 0.024 14.3 1.2 5.5 5 1 1 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FA_hydroxylase PF04116.8 EME32410.1 - 1.7e-18 67.0 18.2 1.7e-18 67.0 12.6 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyoxalase PF00903.20 EME32411.1 - 1.4e-13 50.9 0.1 9.9e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME32411.1 - 1.5e-10 41.0 0.1 0.00015 21.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EME32411.1 - 2.1e-09 37.4 0.3 9e-09 35.3 0.1 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_2 PF12681.2 EME32411.1 - 5.9e-09 36.5 0.0 0.00021 21.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EME32411.1 - 4.4e-05 23.4 0.0 0.3 10.9 0.0 2.7 1 1 1 2 2 2 2 Glyoxalase-like domain ABC_ATPase PF09818.4 EME32412.1 - 8.5e-185 614.5 0.0 1.1e-184 614.2 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EME32412.1 - 0.0041 16.5 0.2 0.026 13.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EME32412.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME32412.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family CDRT4 PF15213.1 EME32413.1 - 0.079 13.0 0.9 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Herpes_UL52 PF03121.10 EME32414.1 - 0.0026 17.4 1.3 0.026 14.2 0.1 2.1 1 1 1 2 2 2 1 Herpesviridae UL52/UL70 DNA primase IL28A PF15177.1 EME32414.1 - 0.074 12.5 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Interleukin-28A E2F_TDP PF02319.15 EME32415.1 - 2.9e-37 126.0 0.8 1.9e-19 68.9 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EME32415.1 - 2.4e-06 27.1 0.0 6.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.6 EME32415.1 - 0.0033 17.0 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 CDC6, C terminal Transcrip_act PF04949.8 EME32415.1 - 0.033 13.8 0.0 0.033 13.8 0.0 3.1 3 1 0 3 3 3 0 Transcriptional activator B-block_TFIIIC PF04182.7 EME32415.1 - 0.065 13.0 0.2 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_17 PF12728.2 EME32415.1 - 0.078 13.2 0.1 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 EME32415.1 - 0.13 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 MarR family S6PP PF05116.8 EME32416.1 - 1.7e-06 27.5 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase DUF829 PF05705.9 EME32418.1 - 1.1e-33 116.9 0.3 2.5e-33 115.7 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EME32418.1 - 0.00049 20.0 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME32418.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MatE PF01554.13 EME32419.1 - 2e-58 196.5 27.0 2e-32 112.0 4.5 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EME32419.1 - 5.9e-06 26.1 44.3 8.5e-05 22.3 13.3 4.5 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Beach PF02138.13 EME32420.1 - 9.7e-82 274.4 2.2 5.9e-81 271.8 1.5 2.2 1 1 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EME32420.1 - 4.9e-09 35.9 0.0 7.8e-08 32.1 0.0 2.7 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EME32420.1 - 0.00029 20.5 0.3 0.00076 19.2 0.2 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 EME32421.1 - 0.082 13.1 5.9 0.15 12.3 4.1 1.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region ATP_sub_h PF10775.4 EME32421.1 - 0.14 11.8 0.5 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 ATP synthase complex subunit h Pkinase PF00069.20 EME32422.1 - 2.1e-55 187.6 0.0 3.7e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32422.1 - 1.2e-28 99.9 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME32422.1 - 6.6e-05 22.0 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME32422.1 - 0.0075 16.0 0.0 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EME32423.1 - 2.1e-55 187.6 0.0 3.7e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32423.1 - 1.2e-28 99.9 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME32423.1 - 6.6e-05 22.0 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME32423.1 - 0.0075 16.0 0.0 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DNA_mis_repair PF01119.14 EME32425.1 - 9.1e-29 99.3 0.0 2.5e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EME32425.1 - 2.5e-14 53.0 0.0 5.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME32425.1 - 3.8e-10 39.4 0.0 7.6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Use1 PF09753.4 EME32426.1 - 4.1e-13 49.3 0.5 6.1e-13 48.7 0.3 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3516 PF12029.3 EME32426.1 - 0.034 12.9 2.7 0.045 12.5 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF2077 PF09850.4 EME32426.1 - 0.034 13.5 0.1 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) HALZ PF02183.13 EME32426.1 - 0.33 10.7 4.0 5.5 6.7 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper BACK PF07707.10 EME32427.1 - 1.3e-14 53.8 1.1 4.6e-14 52.0 0.8 2.0 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EME32427.1 - 1.3e-12 47.6 0.3 6.8e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Methyltransf_FA PF12248.3 EME32427.1 - 1.4e-06 28.2 0.1 3.4e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase F5_F8_type_C PF00754.20 EME32427.1 - 9.1e-06 25.5 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain B_lectin PF01453.19 EME32427.1 - 0.048 13.5 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 D-mannose binding lectin zf-HC5HC2H PF13771.1 EME32428.1 - 1.7e-10 40.8 7.9 1.7e-10 40.8 5.5 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain Exo_endo_phos PF03372.18 EME32429.1 - 1.4e-15 57.9 0.0 5e-15 56.1 0.0 1.9 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME32429.1 - 2.1e-12 46.6 0.0 4.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EME32429.1 - 3.4e-12 46.0 0.8 1.1e-11 44.3 0.5 2.0 1 0 0 1 1 1 1 GRF zinc finger DUF4646 PF15496.1 EME32429.1 - 0.055 13.5 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) DUF563 PF04577.9 EME32430.1 - 7.7e-17 61.8 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PCMT PF01135.14 EME32432.1 - 1.4e-32 112.9 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BTB PF00651.26 EME32432.1 - 6.5e-17 61.5 0.5 1.5e-16 60.3 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain Methyltransf_18 PF12847.2 EME32432.1 - 1.8e-11 44.5 0.1 6.3e-11 42.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME32432.1 - 5e-09 35.9 0.1 1.2e-08 34.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME32432.1 - 7.7e-09 35.6 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME32432.1 - 1.9e-06 27.1 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EME32432.1 - 4.1e-05 23.9 0.0 0.00015 22.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME32432.1 - 0.0001 22.0 0.0 0.00027 20.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME32432.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME32432.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME32432.1 - 0.00019 20.6 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EME32432.1 - 0.00037 19.6 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 EME32432.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EME32432.1 - 0.00081 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EME32432.1 - 0.0047 16.3 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 EME32432.1 - 0.011 16.1 0.0 0.042 14.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EME32432.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EME32432.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Lyase_1 PF00206.15 EME32433.1 - 6.9e-74 248.8 0.0 8.6e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EME32433.1 - 9.7e-22 76.8 0.0 2.9e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Herpes_UL20 PF04544.7 EME32433.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 RRM_1 PF00076.17 EME32434.1 - 6.7e-13 48.0 0.0 1.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32434.1 - 1.7e-10 40.7 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_5 PF13719.1 EME32434.1 - 7e-08 31.9 1.0 3.6e-07 29.6 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EME32434.1 - 3.1e-07 29.9 0.7 1.1e-06 28.2 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain RRM_5 PF13893.1 EME32434.1 - 3.1e-07 30.1 0.0 8.9e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mu-like_Com PF10122.4 EME32434.1 - 0.019 14.0 0.9 0.39 9.7 0.2 2.4 1 1 1 2 2 2 0 Mu-like prophage protein Com Elf1 PF05129.8 EME32434.1 - 0.031 13.9 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DNA_RNApol_7kD PF03604.8 EME32434.1 - 0.036 13.5 0.3 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF1699 PF08004.6 EME32434.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) YABBY PF04690.8 EME32434.1 - 0.054 13.7 0.1 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 YABBY protein OrfB_Zn_ribbon PF07282.6 EME32434.1 - 0.11 12.2 0.5 0.34 10.6 0.2 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EME32434.1 - 0.74 9.8 2.7 2.8 7.9 0.1 2.6 2 1 1 3 3 3 0 Zinc ribbon domain DUF2387 PF09526.5 EME32434.1 - 2.1 8.3 5.6 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Alba PF01918.16 EME32435.1 - 2.9e-10 39.6 0.8 2e-09 36.9 0.3 2.0 2 0 0 2 2 2 1 Alba LptC PF06835.8 EME32435.1 - 0.032 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related Rpp20 PF12328.3 EME32435.1 - 0.13 11.8 0.4 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Prefoldin PF02996.12 EME32437.1 - 1.2e-29 102.4 2.2 1.5e-29 102.1 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EME32437.1 - 2.6e-05 23.9 8.8 0.00028 20.6 2.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit Muted PF14942.1 EME32437.1 - 0.0095 15.8 3.2 0.23 11.3 0.2 2.1 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein Fib_alpha PF08702.5 EME32437.1 - 0.014 15.5 6.2 0.23 11.5 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4618 PF15397.1 EME32437.1 - 0.014 14.7 7.3 0.21 10.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Syntaxin PF00804.20 EME32437.1 - 0.016 15.3 1.9 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 Syntaxin Prefoldin_3 PF13758.1 EME32437.1 - 0.023 14.4 1.2 0.083 12.6 0.8 1.9 1 1 0 1 1 1 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EME32437.1 - 0.034 13.9 0.5 5.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4456 PF14644.1 EME32437.1 - 0.037 13.2 3.7 0.89 8.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) Med9 PF07544.8 EME32437.1 - 0.049 13.3 5.4 0.27 10.9 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF883 PF05957.8 EME32437.1 - 0.065 13.6 2.4 2.1 8.8 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TPD52 PF04201.10 EME32437.1 - 0.066 12.9 8.3 0.21 11.3 1.2 2.1 1 1 1 2 2 2 0 Tumour protein D52 family Syntaxin-6_N PF09177.6 EME32437.1 - 0.087 13.2 2.1 5.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Streptin-Immun PF11083.3 EME32437.1 - 0.094 12.7 3.4 0.94 9.5 0.3 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 EME32437.1 - 0.13 10.1 3.4 0.24 9.2 2.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tektin PF03148.9 EME32437.1 - 0.15 10.5 4.4 0.78 8.2 0.3 2.1 2 0 0 2 2 2 0 Tektin family Snapin_Pallidin PF14712.1 EME32437.1 - 0.18 12.1 5.8 1.7 9.0 0.3 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CENP-F_leu_zip PF10473.4 EME32437.1 - 0.21 11.4 8.7 1.3 8.8 1.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EME32437.1 - 0.22 10.1 5.5 1.9 7.0 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Snf7 PF03357.16 EME32437.1 - 0.22 10.8 6.2 0.25 10.7 1.8 2.1 2 0 0 2 2 2 0 Snf7 FbpA PF05833.6 EME32437.1 - 0.24 9.9 6.0 2.9 6.3 2.3 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) FlaC_arch PF05377.6 EME32437.1 - 0.29 11.0 3.5 7.1 6.6 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.11 EME32437.1 - 0.37 10.8 10.6 0.97 9.4 2.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein COG5 PF10392.4 EME32437.1 - 0.4 10.6 9.0 0.73 9.7 0.7 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF2968 PF11180.3 EME32437.1 - 0.42 9.9 5.7 0.18 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF641 PF04859.7 EME32437.1 - 0.46 10.2 4.4 1.7 8.4 0.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Siah-Interact_N PF09032.6 EME32437.1 - 0.53 10.3 8.8 0.088 12.8 1.8 2.3 2 1 0 2 2 2 0 Siah interacting protein, N terminal Tnp_P_element PF12017.3 EME32437.1 - 0.64 9.1 3.9 4.7 6.3 0.2 2.1 2 0 0 2 2 2 0 Transposase protein Cep57_MT_bd PF06657.8 EME32437.1 - 0.77 9.7 9.6 0.69 9.8 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nnf1 PF03980.9 EME32437.1 - 0.8 9.7 5.3 2.9 7.9 0.7 2.3 2 0 0 2 2 2 0 Nnf1 TMF_DNA_bd PF12329.3 EME32437.1 - 0.86 9.4 9.3 5.4 6.8 3.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EME32437.1 - 0.89 9.3 11.9 3.3 7.5 2.6 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper Surfac_D-trimer PF09006.6 EME32437.1 - 1.1 9.0 4.0 8.1 6.2 0.2 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Occludin_ELL PF07303.8 EME32437.1 - 1.1 10.0 5.6 11 6.8 0.6 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF3552 PF12072.3 EME32437.1 - 1.2 8.3 7.7 4.6 6.3 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ADIP PF11559.3 EME32437.1 - 1.2 9.0 8.1 1.1 9.1 0.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mst1_SARAH PF11629.3 EME32437.1 - 1.7 8.5 8.8 4.6 7.1 1.3 3.3 2 2 1 3 3 3 0 C terminal SARAH domain of Mst1 Val_tRNA-synt_C PF10458.4 EME32437.1 - 1.8 8.6 5.3 2.5 8.2 0.8 2.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SNF2_N PF00176.18 EME32438.1 - 3e-73 246.2 0.0 4.2e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME32438.1 - 1.1e-13 50.7 0.0 2.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EME32438.1 - 1.7e-08 34.1 11.0 3.6e-08 33.1 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME32438.1 - 2.1e-08 33.6 9.9 3.8e-08 32.8 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME32438.1 - 5.4e-08 32.3 9.9 1.1e-07 31.3 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME32438.1 - 7.5e-08 32.2 11.9 1.6e-07 31.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EME32438.1 - 3.4e-07 29.9 0.0 1.4e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EME32438.1 - 2.1e-05 24.1 9.1 4.3e-05 23.1 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EME32438.1 - 0.00063 19.2 5.0 0.0016 17.9 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EME32438.1 - 0.00091 19.0 11.7 0.0025 17.6 8.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME32438.1 - 0.0013 18.3 8.3 0.0019 17.9 5.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EME32438.1 - 0.0023 17.4 8.7 0.0051 16.3 6.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EME32438.1 - 0.0038 16.6 8.1 0.011 15.2 5.6 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger HIRAN PF08797.6 EME32438.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain zf-RING_6 PF14835.1 EME32438.1 - 0.51 10.1 6.6 1.8 8.4 4.6 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF221 PF02714.10 EME32439.1 - 1.5e-47 162.0 4.6 1.5e-47 162.0 3.2 2.8 2 1 0 2 2 2 1 Domain of unknown function DUF221 Nipped-B_C PF12830.2 EME32440.1 - 1.3e-09 37.9 5.0 1.7e-07 31.0 0.0 4.3 4 1 1 5 5 5 2 Sister chromatid cohesion C-terminus Cnd1 PF12717.2 EME32440.1 - 0.0038 17.0 0.5 0.0038 17.0 0.3 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EME32440.1 - 0.02 15.1 0.0 2.5 8.4 0.1 4.3 4 1 1 5 5 5 0 HEAT repeats HEAT PF02985.17 EME32440.1 - 0.031 14.3 4.8 23 5.3 0.1 5.3 6 0 0 6 6 6 0 HEAT repeat DUF3145 PF11343.3 EME32440.1 - 0.05 13.0 0.2 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Cohesin_HEAT PF12765.2 EME32440.1 - 0.14 12.1 9.4 0.076 12.9 0.7 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Fructosamin_kin PF03881.9 EME32441.1 - 1.4e-92 309.7 0.0 1.6e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EME32441.1 - 4e-10 39.8 0.0 4.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME32441.1 - 0.0026 16.9 0.0 0.0058 15.8 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EME32442.1 - 1.4e-85 286.7 0.0 1.7e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EME32442.1 - 3.6e-10 39.9 0.0 4.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME32442.1 - 0.0024 17.0 0.0 0.0054 15.9 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Zn_clus PF00172.13 EME32443.1 - 2.6e-05 24.0 8.9 2.6e-05 24.0 6.2 2.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_8 PF13188.1 EME32443.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain Zn_clus PF00172.13 EME32444.1 - 2.3e-05 24.2 8.9 2.3e-05 24.2 6.2 2.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_8 PF13188.1 EME32444.1 - 0.013 15.3 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Amidinotransf PF02274.12 EME32445.1 - 6.5e-69 232.1 0.1 3.4e-62 210.0 0.0 2.1 2 0 0 2 2 2 2 Amidinotransferase Bax1-I PF01027.15 EME32449.1 - 1.3e-27 96.8 19.1 1.4e-27 96.6 13.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PUF PF00806.14 EME32450.1 - 4.4e-14 51.0 5.2 7.3e-05 22.0 0.1 7.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF1943 PF09172.6 EME32450.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FoP_duplication PF13865.1 EME32451.1 - 6.7e-05 23.2 13.9 0.00055 20.3 9.6 2.2 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 F-protein PF00469.15 EME32451.1 - 0.44 9.8 5.0 0.47 9.7 3.4 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef HTH_3 PF01381.17 EME32451.1 - 0.97 9.3 4.1 0.54 10.1 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix DUF4337 PF14235.1 EME32451.1 - 8.2 6.2 6.3 9.2 6.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Takusan PF04822.8 EME32451.1 - 8.3 6.2 11.2 15 5.3 4.8 2.2 1 1 1 2 2 2 0 Takusan NCKAP5 PF15246.1 EME32452.1 - 0.68 9.2 5.1 0.82 8.9 3.5 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein HTH_3 PF01381.17 EME32452.1 - 1.2 9.0 3.9 0.63 9.9 0.3 2.1 2 0 0 2 2 2 0 Helix-turn-helix FoP_duplication PF13865.1 EME32452.1 - 3 8.3 13.2 26 5.3 9.1 2.1 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pyr_redox_2 PF07992.9 EME32453.1 - 0.00013 21.9 0.0 0.00065 19.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME32453.1 - 0.00099 19.2 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EME32453.1 - 0.056 13.7 0.2 5.7 7.2 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Phosphonate-bd PF12974.2 EME32454.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein MVP_shoulder PF11978.3 EME32454.1 - 0.077 12.8 0.2 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Shoulder domain MVP_shoulder PF11978.3 EME32455.1 - 0.081 12.8 0.2 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Shoulder domain Phosphonate-bd PF12974.2 EME32455.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein ADK PF00406.17 EME32456.1 - 4.9e-26 91.4 0.0 6.1e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EME32456.1 - 1e-07 32.7 0.0 1.3e-07 32.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME32456.1 - 0.00079 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME32456.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.9 EME32456.1 - 0.0031 17.1 1.3 0.0031 17.1 0.9 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid AAA_28 PF13521.1 EME32456.1 - 0.027 14.4 0.1 0.75 9.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain Acetyltransf_9 PF13527.1 EME32457.1 - 1.2e-21 76.9 0.0 5.5e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME32457.1 - 4.8e-08 33.0 0.0 2.2e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME32457.1 - 2e-07 31.1 0.1 4.6e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME32457.1 - 7.6e-07 29.0 0.0 2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME32457.1 - 0.0003 20.4 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.1 EME32457.1 - 0.00095 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.1 EME32458.1 - 5.3e-19 68.3 0.0 2.5e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME32458.1 - 1.3e-07 31.6 0.0 5.7e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME32458.1 - 4e-07 30.1 0.1 9e-06 25.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME32458.1 - 1.4e-06 28.2 0.0 3.2e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME32458.1 - 0.00089 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.1 EME32458.1 - 0.00098 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.1 EME32458.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tnp_DNA_bind PF14706.1 EME32458.1 - 0.2 11.3 1.1 0.31 10.7 0.2 1.7 2 0 0 2 2 2 0 Transposase DNA-binding Aa_trans PF01490.13 EME32461.1 - 1.1e-38 132.7 33.4 1.3e-38 132.5 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EME32461.1 - 0.00016 20.4 27.2 0.00016 20.4 18.9 1.9 1 1 1 2 2 2 1 Spore germination protein KASH PF10541.4 EME32461.1 - 0.034 13.9 0.1 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Nuclear envelope localisation domain Aa_trans PF01490.13 EME32462.1 - 1.1e-38 132.7 33.4 1.3e-38 132.5 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EME32462.1 - 0.00016 20.4 27.2 0.00016 20.4 18.9 1.9 1 1 1 2 2 2 1 Spore germination protein KASH PF10541.4 EME32462.1 - 0.034 13.9 0.1 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Nuclear envelope localisation domain DUF3099 PF11298.3 EME32463.1 - 0.04 13.6 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) PIF PF05092.7 EME32463.1 - 0.071 11.4 0.1 0.073 11.4 0.1 1.0 1 0 0 1 1 1 0 Per os infectivity tRNA_anti-like PF12869.2 EME32463.1 - 0.1 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 tRNA_anti-like Cyclin_C PF02984.14 EME32463.1 - 0.11 12.4 0.9 0.12 12.2 0.6 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain RNA_pol_Rpb4 PF03874.11 EME32464.1 - 4.9e-20 71.6 0.1 6.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ank_2 PF12796.2 EME32465.1 - 5.7e-17 61.8 0.0 1.4e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME32465.1 - 7.8e-17 60.1 0.3 1.2e-10 40.6 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EME32465.1 - 1.4e-09 37.8 2.2 4.5e-07 29.8 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME32465.1 - 9.7e-08 31.5 0.1 2.8e-06 27.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat ANTH PF07651.11 EME32465.1 - 1.9e-06 26.7 6.2 0.15 10.7 0.0 4.1 2 1 1 3 3 3 3 ANTH domain Ank_4 PF13637.1 EME32465.1 - 1.7e-05 25.2 0.0 4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ENTH PF01417.15 EME32465.1 - 0.00048 19.9 0.1 0.0055 16.5 0.1 2.5 1 1 0 1 1 1 1 ENTH domain Ank_2 PF12796.2 EME32466.1 - 5.7e-17 61.8 0.0 1.4e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME32466.1 - 7.8e-17 60.1 0.3 1.2e-10 40.6 0.2 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EME32466.1 - 1.4e-09 37.8 2.2 4.5e-07 29.8 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) ANTH PF07651.11 EME32466.1 - 5e-08 31.9 6.3 0.15 10.7 0.0 4.2 2 1 0 3 3 3 3 ANTH domain Ank_3 PF13606.1 EME32466.1 - 9.7e-08 31.5 0.1 2.8e-06 27.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EME32466.1 - 1.7e-05 25.2 0.0 4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ENTH PF01417.15 EME32466.1 - 0.0006 19.6 0.9 0.0055 16.5 0.1 2.8 2 1 0 2 2 2 1 ENTH domain Gam PF06064.6 EME32466.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam GATA PF00320.22 EME32467.1 - 7.7e-15 53.9 6.7 1.7e-14 52.8 4.7 1.6 1 0 0 1 1 1 1 GATA zinc finger CTP_synth_N PF06418.9 EME32468.1 - 3.1e-121 403.6 0.0 4.1e-121 403.2 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EME32468.1 - 6.1e-49 166.0 0.0 1e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EME32468.1 - 1.9e-06 27.4 0.0 6.3e-05 22.5 0.0 2.5 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 EME32468.1 - 0.00067 19.1 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.14 EME32468.1 - 0.1 12.2 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 SNO glutamine amidotransferase family CTP_synth_N PF06418.9 EME32469.1 - 3.3e-121 403.6 0.0 4.4e-121 403.1 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EME32469.1 - 5.1e-48 163.0 0.0 1.1e-47 161.9 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EME32469.1 - 2.1e-06 27.3 0.0 6.7e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 EME32469.1 - 0.00071 19.0 0.0 0.002 17.5 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.14 EME32469.1 - 0.11 12.0 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 SNO glutamine amidotransferase family zf-C3HC4_3 PF13920.1 EME32470.1 - 3.9e-13 48.8 6.1 3.9e-13 48.8 4.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME32470.1 - 0.0002 21.0 7.6 0.0002 21.0 5.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME32470.1 - 0.00036 20.5 9.8 0.00097 19.1 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME32470.1 - 0.0062 16.0 3.8 0.013 14.9 2.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EME32470.1 - 0.73 9.7 14.8 0.033 14.0 6.2 1.8 2 0 0 2 2 2 0 Ring finger domain ThiF PF00899.16 EME32471.1 - 9e-38 129.1 0.0 1.6e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 EME32471.1 - 3.3e-18 64.7 0.9 6.8e-18 63.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 EME32471.1 - 7.1e-16 57.5 0.2 1.4e-15 56.6 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EME32471.1 - 2.1e-05 24.5 0.2 7.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EME32471.1 - 0.016 15.4 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME32471.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EME32472.1 - 8.3e-38 129.2 0.0 1.5e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 EME32472.1 - 3.1e-18 64.8 0.9 6.5e-18 63.8 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 EME32472.1 - 6.8e-16 57.6 0.2 1.3e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EME32472.1 - 2e-05 24.6 0.1 7.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EME32472.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME32472.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SRP_SPB PF02978.14 EME32473.1 - 0.011 15.9 0.1 0.02 15.1 0.1 1.4 1 0 0 1 1 1 0 Signal peptide binding domain Metallophos PF00149.23 EME32474.1 - 4.7e-08 32.6 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME32474.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PTR2 PF00854.16 EME32475.1 - 9.7e-32 110.1 9.9 1.1e-19 70.4 0.1 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.11 EME32475.1 - 1.5e-12 46.8 10.6 1.3e-07 30.6 1.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.16 EME32476.1 - 5e-66 222.8 0.0 6.9e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF4379 PF14311.1 EME32477.1 - 5.4e-05 22.9 10.4 0.0062 16.3 2.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4379) Redoxin PF08534.5 EME32477.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.3 3 0 0 3 3 3 0 Redoxin DUF953 PF06110.6 EME32477.1 - 0.77 9.2 3.9 3.6 7.0 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) ADK PF00406.17 EME32478.1 - 4.4e-65 218.1 0.0 1.1e-48 164.9 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 EME32478.1 - 2.6e-16 60.5 0.0 3.4e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EME32478.1 - 3.2e-10 40.0 0.0 4.8e-07 29.7 0.0 3.4 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EME32478.1 - 1.1e-09 38.7 0.0 1.6e-06 28.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ADK_lid PF05191.9 EME32478.1 - 6.6e-05 22.4 1.7 0.00011 21.7 0.0 2.4 3 0 0 3 3 2 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 EME32478.1 - 0.00063 18.8 0.0 0.037 13.1 0.0 2.8 2 1 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 EME32478.1 - 0.0018 17.6 2.6 0.83 8.9 0.0 3.6 3 1 0 3 3 3 2 Thymidylate kinase AAA_19 PF13245.1 EME32478.1 - 0.0054 16.4 0.1 2.2 8.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 EME32478.1 - 0.01 16.0 0.0 3 8.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 EME32478.1 - 0.042 13.3 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_28 PF13521.1 EME32478.1 - 0.045 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Cys_rich_KTR PF14205.1 EME32478.1 - 0.089 12.2 0.2 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich KTR SKI PF01202.17 EME32478.1 - 0.11 12.3 0.3 3.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase Dynamin_N PF00350.18 EME32478.1 - 0.16 11.7 0.0 0.76 9.5 0.0 2.1 2 1 0 2 2 2 0 Dynamin family DUF3054 PF11255.3 EME32478.1 - 0.24 11.2 3.4 0.43 10.4 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) DP PF08781.5 EME32479.1 - 1e-24 86.8 6.3 2.2e-24 85.7 3.1 2.3 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.15 EME32479.1 - 1.8e-21 75.4 0.8 4.6e-21 74.1 0.6 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EME32479.1 - 0.015 14.9 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Seadorna_VP6 PF07407.6 EME32479.1 - 0.018 13.8 0.5 0.028 13.1 0.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein IcmF-related PF06761.7 EME32479.1 - 0.062 12.5 0.2 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing HTH_29 PF13551.1 EME32479.1 - 0.095 12.8 1.7 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix PMT PF02366.13 EME32480.1 - 5.7e-39 133.9 20.0 5.7e-39 133.9 13.9 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Rad51 PF08423.6 EME32481.1 - 1.5e-127 423.8 0.1 1.8e-127 423.5 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EME32481.1 - 1.1e-12 47.7 0.1 1.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EME32481.1 - 1.4e-10 40.8 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME32481.1 - 6.7e-08 31.9 0.1 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 EME32481.1 - 0.0016 18.5 0.0 0.0056 16.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EME32481.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 EME32481.1 - 0.083 12.2 0.0 0.66 9.3 0.0 2.2 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Rad51 PF08423.6 EME32482.1 - 6.1e-125 415.2 0.1 7.6e-125 414.9 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EME32482.1 - 1e-11 44.5 0.1 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EME32482.1 - 3.9e-10 39.4 0.0 5.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME32482.1 - 3.7e-08 32.7 0.1 6.5e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 EME32482.1 - 0.0017 18.5 0.0 0.0057 16.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EME32482.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 EME32482.1 - 0.1 11.9 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RRM_1 PF00076.17 EME32483.1 - 3.3e-31 106.7 3.0 3.5e-16 58.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32483.1 - 9.7e-26 89.5 0.3 6.6e-16 58.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME32483.1 - 4.6e-18 64.8 1.2 8e-08 32.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME32483.1 - 2.1e-08 33.9 0.8 0.018 14.8 0.0 3.7 3 0 0 3 3 3 3 RNA binding motif DUF4566 PF15130.1 EME32484.1 - 0.096 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) DUF3598 PF12204.3 EME32485.1 - 4.9e-13 48.8 0.4 2.7e-12 46.4 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3598) HTS PF04204.11 EME32486.1 - 0.097 11.3 0.0 0.24 10.1 0.0 1.5 1 1 1 2 2 2 0 Homoserine O-succinyltransferase SNARE_assoc PF09335.6 EME32487.1 - 4.6e-27 94.6 8.6 4.6e-27 94.6 6.0 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein EMP24_GP25L PF01105.19 EME32488.1 - 5e-29 101.3 0.0 6.2e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD THDPS_N_2 PF14805.1 EME32488.1 - 0.022 14.5 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Baculo_11_kDa PF06143.6 EME32488.1 - 0.049 12.9 0.5 0.049 12.9 0.4 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family EMP24_GP25L PF01105.19 EME32489.1 - 1.7e-15 57.1 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD THDPS_N_2 PF14805.1 EME32489.1 - 0.0065 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Pyr_redox_2 PF07992.9 EME32490.1 - 2.9e-17 63.2 0.0 5.3e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME32490.1 - 4e-06 27.1 0.1 0.0036 17.6 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME32490.1 - 1.1e-05 24.6 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EME32490.1 - 0.0011 19.0 0.0 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EME32490.1 - 0.02 14.9 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_7 PF13241.1 EME32490.1 - 0.029 14.6 1.9 0.44 10.8 0.1 3.1 4 0 0 4 4 4 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EME32490.1 - 0.053 13.3 0.0 12 5.5 0.0 2.4 1 1 1 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME32490.1 - 0.26 11.3 0.7 18 5.4 0.0 3.1 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF3493 PF11998.3 EME32491.1 - 2.4e-15 56.1 0.5 4.6e-15 55.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3493) Claudin_2 PF13903.1 EME32491.1 - 0.051 13.2 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PHD PF00628.24 EME32492.1 - 3.1e-06 26.7 1.9 3.1e-06 26.7 1.3 1.8 2 0 0 2 2 2 1 PHD-finger JmjC PF02373.17 EME32492.1 - 5.4e-06 26.6 2.0 0.00026 21.1 0.3 3.3 2 2 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EME32492.1 - 3.7e-05 23.3 0.2 0.00016 21.3 0.2 2.0 1 1 0 1 1 1 1 Cupin-like domain GPI PF06560.6 EME32492.1 - 0.045 12.7 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF45 PF01863.12 EME32494.1 - 0.07 12.9 0.2 2 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 HD PF01966.17 EME32495.1 - 3.2e-11 43.3 0.1 2.6e-10 40.3 0.0 2.5 2 1 0 2 2 2 1 HD domain FAM180 PF15173.1 EME32495.1 - 0.064 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FAM180 family CcmH PF03918.9 EME32496.1 - 1.6e-18 66.0 0.0 2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein Cse1 PF08506.5 EME32497.1 - 4e-10 38.8 0.2 2.2e-09 36.3 0.1 2.2 2 1 0 2 2 2 1 Cse1 IBN_N PF03810.14 EME32497.1 - 2.1e-09 37.1 0.5 1.1e-08 34.9 0.3 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EME32497.1 - 5.9e-05 23.0 5.6 0.00011 22.1 0.4 3.6 4 0 0 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.2 EME32497.1 - 0.023 14.5 2.4 0.65 9.8 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EME32497.1 - 0.03 14.5 0.0 0.42 10.9 0.0 3.0 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EME32497.1 - 0.13 12.3 0.5 47 4.4 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat UNC45-central PF11701.3 EME32497.1 - 0.2 11.2 3.3 17 5.0 0.0 4.4 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central HEAT PF02985.17 EME32498.1 - 1.3e-42 140.0 29.9 0.0038 17.1 0.0 13.6 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EME32498.1 - 9.1e-30 102.7 4.1 2.7e-06 27.5 0.0 6.5 2 1 5 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 EME32498.1 - 9.6e-12 45.0 7.4 0.85 10.1 0.0 9.0 8 2 1 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME32498.1 - 7.5e-11 42.2 8.7 0.085 13.2 0.0 7.2 3 2 5 8 8 8 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EME32498.1 - 0.0014 18.5 9.8 0.052 13.3 0.4 5.1 3 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EME32498.1 - 0.0059 16.4 4.7 0.35 10.7 0.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) AAA_17 PF13207.1 EME32499.1 - 1.7e-06 28.8 0.0 1.7e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME32499.1 - 1.1e-05 25.7 0.1 1.1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EME32499.1 - 2.9e-05 23.9 0.1 3.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EME32499.1 - 0.00024 21.0 0.0 0.00024 21.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME32499.1 - 0.00053 19.1 0.0 0.00053 19.1 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EME32499.1 - 0.0064 16.2 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 NTPase APS_kinase PF01583.15 EME32499.1 - 0.0067 16.0 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_24 PF13479.1 EME32499.1 - 0.0092 15.5 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EME32499.1 - 0.011 14.5 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.10 EME32499.1 - 0.017 14.1 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_31 PF13614.1 EME32499.1 - 0.028 14.3 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME32499.1 - 0.028 14.3 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME32499.1 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 EME32499.1 - 0.057 12.9 0.1 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EME32499.1 - 0.058 13.5 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME32499.1 - 0.078 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EME32499.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MoCF_biosynth PF00994.19 EME32499.1 - 0.14 11.5 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Probable molybdopterin binding domain AAA_22 PF13401.1 EME32499.1 - 0.2 11.7 0.7 0.21 11.7 0.5 1.4 1 1 0 1 1 1 0 AAA domain Bax1-I PF01027.15 EME32500.1 - 4.3e-46 157.1 34.6 5e-46 156.8 23.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 FtsJ PF01728.14 EME32501.1 - 2.6e-53 180.6 0.0 5.5e-53 179.6 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 EME32501.1 - 1.1e-38 132.9 33.5 1.1e-38 132.9 23.2 3.1 4 0 0 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 EME32501.1 - 6.5e-29 100.4 8.6 6.5e-29 100.4 5.9 4.9 2 1 2 5 5 5 1 Domain of unknown function (DUF3381) ATP_bind_3 PF01171.15 EME32503.1 - 6.2e-19 68.1 0.0 9.3e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EME32503.1 - 0.0008 19.7 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EME32503.1 - 0.013 14.0 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 EME32503.1 - 0.046 13.5 0.0 0.27 11.0 0.0 2.0 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family NUC153 PF08159.7 EME32504.1 - 6.7e-09 35.1 0.7 1.4e-08 34.2 0.5 1.5 1 0 0 1 1 1 1 NUC153 domain DUF645 PF04875.7 EME32505.1 - 0.027 14.1 0.0 0.081 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF645 ubiquitin PF00240.18 EME32506.1 - 5.5e-11 41.7 0.0 1.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EME32506.1 - 2.9e-09 36.4 0.4 1.6e-08 34.1 0.3 2.4 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EME32506.1 - 8.9e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME32506.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain HTH_8 PF02954.14 EME32506.1 - 0.093 12.2 0.3 0.65 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CUE PF02845.11 EME32506.1 - 0.1 12.0 3.9 0.76 9.3 0.1 3.7 3 0 0 3 3 3 0 CUE domain Cohesin_HEAT PF12765.2 EME32506.1 - 0.4 10.6 3.6 5.2 7.1 0.0 4.0 4 1 1 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DUF3417 PF11897.3 EME32506.1 - 0.42 10.5 4.9 4 7.4 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) DUF1313 PF07011.6 EME32506.1 - 1.1 9.0 8.6 0.8 9.4 0.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1313) ComX PF05952.7 EME32506.1 - 1.1 8.7 4.6 23 4.5 0.1 4.3 4 1 2 6 6 6 0 Bacillus competence pheromone ComX Methyltransf_31 PF13847.1 EME32507.1 - 6.3e-12 45.3 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME32507.1 - 6.8e-12 45.7 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME32507.1 - 1.6e-10 41.5 0.0 2.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME32507.1 - 1.3e-09 37.9 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME32507.1 - 1.4e-08 34.9 0.0 7.7e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME32507.1 - 1.9e-06 28.2 0.0 3.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME32507.1 - 7.1e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EME32507.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME32507.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EME32507.1 - 0.058 12.9 0.1 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_11 PF08241.7 EME32508.1 - 6.5e-08 32.9 0.0 2.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain THOC7 PF05615.8 EME32508.1 - 1.1e-07 32.1 13.4 1.1e-07 32.1 9.3 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 Methyltransf_25 PF13649.1 EME32508.1 - 0.00047 20.4 0.6 0.0032 17.8 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Mnd1 PF03962.10 EME32508.1 - 0.0024 17.5 16.3 0.0049 16.5 11.3 1.5 1 0 0 1 1 1 1 Mnd1 family Methyltransf_31 PF13847.1 EME32508.1 - 0.0071 15.9 0.8 0.023 14.2 0.5 2.3 1 1 1 2 2 2 1 Methyltransferase domain Zeta_toxin PF06414.7 EME32508.1 - 0.038 13.0 3.6 0.086 11.9 2.5 1.6 1 0 0 1 1 1 0 Zeta toxin LPAM_2 PF13627.1 EME32508.1 - 0.087 12.5 0.1 0.087 12.5 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site Methyltransf_12 PF08242.7 EME32508.1 - 0.093 13.2 0.3 0.54 10.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF948 PF06103.6 EME32508.1 - 0.71 9.7 8.1 0.5 10.2 0.5 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EME32508.1 - 0.9 7.3 12.2 1.3 6.7 8.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 6PGD PF00393.14 EME32509.1 - 6e-113 376.8 0.0 8.4e-113 376.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EME32509.1 - 2.4e-49 167.2 0.0 3.8e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EME32509.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME32509.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EME32509.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EME32509.1 - 0.016 14.8 0.0 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FabA PF07977.8 EME32510.1 - 0.016 14.7 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 FabA-like domain ATE_C PF04377.10 EME32511.1 - 2e-42 144.2 1.3 4.4e-42 143.1 0.9 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EME32511.1 - 9.2e-26 89.4 1.1 2.9e-25 87.8 0.8 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF313 PF03754.8 EME32511.1 - 0.017 15.0 0.7 0.8 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF313) RTX_C PF08339.5 EME32511.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RTX C-terminal domain Cyclin_N PF00134.18 EME32512.1 - 1.8e-09 37.2 0.4 1.2e-08 34.5 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain MCM PF00493.18 EME32513.1 - 1.1e-128 428.7 0.0 2.3e-128 427.6 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME32513.1 - 3.6e-24 85.5 1.8 6.1e-24 84.8 0.4 2.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME32513.1 - 3.8e-07 29.4 0.1 0.00013 21.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME32513.1 - 3.7e-06 26.7 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME32513.1 - 0.0013 18.3 0.3 0.0056 16.2 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EME32513.1 - 0.077 13.4 0.0 0.51 10.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Tim17 PF02466.14 EME32514.1 - 0.0073 16.3 0.7 0.028 14.4 0.5 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Matrilin_ccoil PF10393.4 EME32515.1 - 0.013 14.8 2.1 0.027 13.8 1.5 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CBM_25 PF03423.8 EME32516.1 - 7.7e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) EF-hand_7 PF13499.1 EME32516.1 - 0.013 15.6 0.3 0.025 14.7 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF3983 PF13137.1 EME32517.1 - 0.68 9.6 2.4 8.5 6.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) Glyco_hydro_31 PF01055.21 EME32518.1 - 1.1e-55 189.2 1.9 1.4e-54 185.6 1.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 EME32518.1 - 1.3e-06 27.4 0.1 9.6e-06 24.5 0.1 1.9 1 1 0 1 1 1 1 Melibiase Raffinose_syn PF05691.7 EME32518.1 - 0.02 12.4 0.0 0.049 11.1 0.0 1.5 2 0 0 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 Alpha-amylase PF00128.19 EME32518.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, catalytic domain TPR_11 PF13414.1 EME32519.1 - 8.5e-34 115.0 23.0 3e-13 49.2 0.1 7.9 7 2 2 9 9 9 7 TPR repeat TPR_2 PF07719.12 EME32519.1 - 2.7e-24 83.0 28.9 3.5e-06 26.4 0.0 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 EME32519.1 - 3.7e-20 70.1 32.3 0.0011 18.5 0.0 11.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME32519.1 - 1.1e-18 66.9 18.8 0.00013 21.8 0.0 7.5 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME32519.1 - 7.5e-18 63.3 36.3 2.2e-06 27.0 0.1 9.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME32519.1 - 3.3e-15 55.1 0.5 0.25 12.1 0.0 8.4 7 3 3 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME32519.1 - 2.8e-12 46.9 5.7 0.00043 20.8 0.0 7.4 7 1 3 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME32519.1 - 4.3e-12 45.2 6.4 0.0023 17.9 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME32519.1 - 3.9e-09 36.3 23.5 3.5 8.2 0.1 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME32519.1 - 5.8e-09 35.0 11.9 0.4 10.6 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME32519.1 - 1.2e-06 28.3 18.4 0.0055 16.5 0.1 7.1 8 0 0 8 8 8 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EME32519.1 - 5.1e-06 26.7 6.4 1.8 8.9 0.1 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME32519.1 - 0.00057 19.7 0.7 49 4.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EME32519.1 - 0.072 13.2 25.9 0.27 11.3 0.3 7.1 4 3 4 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.27 EME32520.1 - 4.6e-53 175.3 19.6 3.7e-09 36.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Glyco_hydro_28 PF00295.12 EME32520.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Nucleoporin_N PF08801.6 EME32520.1 - 0.0033 16.2 0.2 4.6 5.8 0.0 3.6 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EME32520.1 - 0.0036 15.4 1.1 1.5 6.8 0.1 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME32520.1 - 0.042 14.1 1.2 4.7 7.6 0.0 3.7 3 1 1 4 4 4 0 PQQ-like domain DAO PF01266.19 EME32522.1 - 2.1e-34 119.0 0.0 5.1e-34 117.7 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME32522.1 - 6.6e-06 25.2 0.0 9.7e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME32522.1 - 0.00032 20.6 0.0 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 EME32522.1 - 0.00096 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 EME32522.1 - 0.00097 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EME32522.1 - 0.0017 17.7 0.1 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EME32522.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EME32522.1 - 0.0064 16.8 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EME32522.1 - 0.0091 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EME32522.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EME32522.1 - 0.049 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME32522.1 - 0.088 11.8 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EME32522.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EME32522.1 - 0.12 10.7 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Clp1 PF06807.9 EME32523.1 - 6.6e-17 61.9 0.1 1.2e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EME32523.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME32523.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EME32523.1 - 0.0045 17.1 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 EME32523.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EME32523.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME32523.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ASXH PF13919.1 EME32523.1 - 0.047 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain AAA_33 PF13671.1 EME32523.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EME32523.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin DUF87 PF01935.12 EME32523.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EME32523.1 - 0.13 13.0 0.0 0.55 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EME32525.1 - 1.1e-48 165.6 0.0 2e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32525.1 - 1e-32 113.2 0.0 1.5e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4641 PF15483.1 EME32525.1 - 0.0019 16.9 0.5 0.0033 16.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4641) Kinase-like PF14531.1 EME32525.1 - 0.0048 15.8 0.0 0.0095 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME32525.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 EME32526.1 - 2.3e-75 253.9 24.9 2.9e-75 253.5 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME32526.1 - 1.6e-24 86.2 26.8 1.6e-24 86.2 18.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily RWP-RK PF02042.10 EME32527.1 - 1.4e-08 34.3 0.0 3.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 RWP-RK domain Phage_hub_GP28 PF11110.3 EME32527.1 - 0.29 10.8 1.3 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Baseplate hub distal subunit Cor1 PF04803.7 EME32527.1 - 8.5 6.1 8.6 2.6 7.8 1.7 2.6 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Glyco_hydro_35 PF01301.14 EME32528.1 - 7.8e-85 285.0 0.1 1.1e-84 284.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 HMG_CoA_synt_C PF08540.5 EME32529.1 - 1.3e-97 326.6 1.3 1.7e-97 326.3 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EME32529.1 - 6.6e-79 263.4 0.4 1.1e-78 262.7 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 EME32529.1 - 0.0005 20.0 0.0 0.046 13.7 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Carboxyl_trans PF01039.17 EME32530.1 - 5.9e-150 499.8 0.0 9.5e-150 499.1 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 EME32530.1 - 7.6e-122 407.7 11.0 5.3e-118 395.0 9.3 2.6 2 1 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 EME32530.1 - 1.9e-50 171.0 0.1 3.6e-50 170.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME32530.1 - 9.8e-27 93.2 0.0 2.5e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME32530.1 - 1.6e-21 76.3 0.0 3.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EME32530.1 - 6.8e-12 45.4 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EME32530.1 - 2e-11 43.3 0.1 4.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 EME32530.1 - 2.7e-06 26.8 0.2 6.6e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EME32530.1 - 3e-06 27.1 0.1 7.7e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME32530.1 - 0.00058 19.3 0.0 0.0018 17.6 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EME32530.1 - 0.0024 17.3 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EME32530.1 - 0.019 14.6 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like DUF2384 PF09722.5 EME32530.1 - 0.15 11.9 1.0 9.9 6.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) HlyD_2 PF12700.2 EME32530.1 - 0.47 9.5 4.6 1.4 8.0 0.1 2.8 2 1 1 3 3 3 0 HlyD family secretion protein DUF2962 PF11176.3 EME32531.1 - 0.043 13.3 1.1 0.058 12.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Pkinase PF00069.20 EME32532.1 - 8.3e-40 136.5 0.1 9.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32532.1 - 5.1e-19 68.3 0.0 6.3e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME32532.1 - 1.4e-05 24.1 0.0 0.055 12.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Archease PF01951.11 EME32532.1 - 0.061 13.2 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) APH PF01636.18 EME32532.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1e PF01406.14 EME32533.1 - 2.1e-107 358.7 1.1 2.2e-107 358.6 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EME32533.1 - 1.2e-10 40.6 0.7 2.8e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EME32533.1 - 0.00056 18.0 0.0 0.0029 15.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) FUSC_2 PF13515.1 EME32534.1 - 4.4e-10 39.5 26.0 1.3e-09 38.0 7.9 2.9 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.3 EME32534.1 - 0.0052 15.4 8.5 0.018 13.7 5.9 1.9 1 0 0 1 1 1 1 Aluminium activated malate transporter CorA PF01544.13 EME32535.1 - 8.7 5.2 9.2 1.4e+02 1.3 6.4 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CorA PF01544.13 EME32536.1 - 0.00018 20.6 0.8 0.00025 20.1 0.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EME32537.1 - 4.5e-06 25.8 0.2 6.7e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Keratin_assoc PF09775.4 EME32538.1 - 6.7e-18 64.5 6.8 8e-18 64.2 4.7 1.0 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 adh_short PF00106.20 EME32539.1 - 3.9e-13 49.6 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME32539.1 - 5.7e-10 39.3 0.0 6.6e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PFK PF00365.15 EME32540.1 - 7e-25 87.5 0.5 1.1e-24 86.9 0.4 1.3 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 EME32540.1 - 0.0034 16.1 0.1 0.0058 15.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EME32540.1 - 0.063 12.7 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF746 PF05344.6 EME32540.1 - 0.072 12.6 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Spermine_synth PF01564.12 EME32541.1 - 1.3e-40 138.8 0.0 2.1e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EME32541.1 - 0.00079 19.0 0.0 0.00091 18.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain F_actin_bind PF08919.5 EME32542.1 - 0.46 10.2 3.3 1.7 8.3 0.1 2.3 1 1 0 2 2 2 0 F-actin binding FGGY_N PF00370.16 EME32543.1 - 2.7e-76 256.1 0.1 3.9e-76 255.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EME32543.1 - 1.5e-60 204.2 0.2 8.8e-60 201.7 0.1 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Fe-ADH PF00465.14 EME32544.1 - 5.2e-55 186.5 0.0 6.8e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME32544.1 - 3.2e-34 118.3 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EME32544.1 - 7.1e-05 21.8 0.2 0.0092 14.9 0.0 2.3 2 0 0 2 2 2 2 3-dehydroquinate synthase OTU PF02338.14 EME32545.1 - 2.2e-11 44.4 0.0 4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.18 EME32545.1 - 2.5e-05 23.5 0.0 7.5e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UN_NPL4 PF11543.3 EME32545.1 - 0.0024 18.1 0.1 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Telomere_Sde2 PF13019.1 EME32545.1 - 0.0029 17.2 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Telomere stability and silencing Ubiquitin_2 PF14560.1 EME32545.1 - 0.0038 17.4 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Peptidase_C65 PF10275.4 EME32545.1 - 0.015 14.6 0.3 0.11 11.8 0.1 1.9 1 1 1 2 2 2 0 Peptidase C65 Otubain Lin-8 PF03353.10 EME32546.1 - 0.034 13.4 13.5 0.0091 15.3 7.1 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.8 EME32546.1 - 8.8 5.4 21.8 1.9 7.6 12.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Abhydrolase_5 PF12695.2 EME32547.1 - 0.00026 20.7 0.0 0.0015 18.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME32547.1 - 0.0093 15.4 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Aminotran_1_2 PF00155.16 EME32548.1 - 3e-45 154.7 0.0 3.8e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME32548.1 - 0.0017 17.1 0.0 0.0036 16.1 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME32548.1 - 0.0026 16.1 0.1 0.0052 15.1 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 EME32548.1 - 0.025 13.0 0.0 0.038 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 EME32548.1 - 0.076 11.5 0.0 0.12 10.8 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EME32548.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EME32548.1 - 0.21 10.5 0.0 15 4.4 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family F-box-like PF12937.2 EME32549.1 - 1.7e-13 50.0 0.2 6.3e-12 45.0 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME32549.1 - 3.9e-08 32.7 0.0 1.5e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain BAR PF03114.13 EME32549.1 - 0.00011 21.8 0.9 0.00024 20.6 0.6 1.5 1 0 0 1 1 1 1 BAR domain PNK3P PF08645.6 EME32549.1 - 0.01 15.2 0.4 0.034 13.5 0.2 1.8 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase HCO3_cotransp PF00955.16 EME32549.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 HCO3- transporter family F-box-like PF12937.2 EME32550.1 - 2e-13 49.8 0.2 6.8e-12 44.9 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME32550.1 - 2.3e-08 33.4 0.1 1.6e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain BAR PF03114.13 EME32550.1 - 0.00014 21.4 2.5 0.00027 20.5 0.6 2.1 2 0 0 2 2 2 1 BAR domain PNK3P PF08645.6 EME32550.1 - 0.011 15.1 0.4 0.036 13.4 0.2 1.9 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase HCO3_cotransp PF00955.16 EME32550.1 - 0.081 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 HCO3- transporter family LpxB PF02684.10 EME32551.1 - 0.015 13.9 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase LpxB PF02684.10 EME32552.1 - 0.015 13.9 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PAP_central PF04928.12 EME32553.1 - 1.1e-102 342.2 0.1 1.8e-102 341.5 0.1 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EME32553.1 - 1.8e-29 102.2 0.1 6.3e-29 100.5 0.1 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EME32553.1 - 3.8e-06 27.1 0.2 1.7e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain IL12 PF03039.9 EME32553.1 - 0.12 11.4 0.6 0.27 10.3 0.4 1.5 1 0 0 1 1 1 0 Interleukin-12 alpha subunit Msg2_C PF12373.3 EME32553.1 - 7 5.9 6.8 4.3 6.6 0.5 3.0 3 0 0 3 3 3 0 Major surface glycoprotein 2 C terminal Mad3_BUB1_I PF08311.7 EME32554.1 - 2.1e-26 92.1 2.0 4e-26 91.2 1.4 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Aminotran_1_2 PF00155.16 EME32555.1 - 1.3e-37 129.6 0.0 6.9e-37 127.2 0.0 1.8 1 1 1 2 2 2 1 Aminotransferase class I and II NADH_B2 PF14813.1 EME32556.1 - 0.003 17.1 0.1 0.0044 16.6 0.1 1.4 1 1 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 BPL_LplA_LipB PF03099.14 EME32557.1 - 1.2e-18 67.3 0.0 2.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EME32557.1 - 0.079 12.6 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Nup35_RRM PF05172.8 EME32558.1 - 2.2e-12 46.6 0.0 6.8e-12 45.0 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EME32558.1 - 9.2e-11 41.3 0.0 1.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif LpxC PF03331.8 EME32559.1 - 6.6e-81 271.2 0.0 8.9e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase His_biosynth PF00977.16 EME32560.1 - 2e-85 285.6 1.6 2.4e-85 285.4 1.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 EME32560.1 - 2.8e-05 23.3 0.6 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI Dus PF01207.12 EME32560.1 - 3.9e-05 22.6 0.1 0.0015 17.4 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NMO PF03060.10 EME32560.1 - 4.4e-05 22.7 5.8 0.0038 16.4 1.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.12 EME32560.1 - 7.4e-05 22.1 0.2 0.0004 19.7 0.0 2.2 2 2 1 3 3 3 1 PcrB family ThiG PF05690.9 EME32560.1 - 0.00012 21.2 0.8 0.027 13.5 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EME32560.1 - 0.0012 17.8 3.0 0.014 14.3 0.0 2.8 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase Slx4 PF09494.5 EME32560.1 - 0.039 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease FMN_dh PF01070.13 EME32560.1 - 0.13 11.0 4.0 0.021 13.6 0.4 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase IMPDH PF00478.20 EME32560.1 - 1.1 8.1 5.1 1.8 7.3 0.1 2.2 1 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain zf-C3HC4_3 PF13920.1 EME32561.1 - 2.3e-16 59.1 10.7 4.2e-16 58.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME32561.1 - 9.1e-08 31.9 12.8 1.9e-07 30.9 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME32561.1 - 1.2e-05 24.9 12.6 5.1e-05 23.0 8.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EME32561.1 - 0.00082 19.0 10.3 0.0016 18.1 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EME32561.1 - 0.0029 17.1 3.7 0.0029 17.1 2.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EME32561.1 - 0.089 12.3 8.4 0.17 11.4 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EME32561.1 - 8.4 5.9 11.6 31 4.1 8.0 1.9 1 1 0 1 1 1 0 P-11 zinc finger FHA PF00498.21 EME32562.1 - 1.2e-14 54.1 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Dsh_C PF12316.3 EME32562.1 - 3.1 7.8 8.6 4.8 7.2 5.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Sugar_tr PF00083.19 EME32563.1 - 1.8e-23 82.8 36.1 4.4e-21 74.9 25.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME32563.1 - 1.7e-10 40.1 59.9 3.3e-08 32.6 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME32563.1 - 9e-05 21.0 9.2 9e-05 21.0 6.4 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein CAF-1_p150 PF11600.3 EME32564.1 - 0.062 12.6 14.4 0.09 12.1 10.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-HC5HC2H PF13771.1 EME32565.1 - 1.7e-13 50.4 14.4 1.7e-13 50.4 10.0 5.4 3 1 2 6 6 6 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EME32565.1 - 2.6e-08 33.8 9.8 2.6e-08 33.8 6.8 4.3 3 1 3 6 6 6 1 PHD-zinc-finger like domain zf-C2H2 PF00096.21 EME32565.1 - 0.51 10.7 57.4 0.19 12.1 1.3 7.4 7 1 0 7 7 7 0 Zinc finger, C2H2 type FUSC_2 PF13515.1 EME32566.1 - 1.4e-07 31.4 33.1 4e-07 29.9 9.9 2.8 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.3 EME32566.1 - 0.0078 14.9 5.6 0.011 14.4 0.1 3.2 3 0 0 3 3 3 1 Aluminium activated malate transporter Pinin_SDK_memA PF04696.8 EME32567.1 - 1.1e-10 41.2 16.5 1.1e-10 41.2 11.5 3.7 2 1 2 4 4 4 1 pinin/SDK/memA/ protein conserved region SAP PF02037.22 EME32567.1 - 0.00021 20.7 2.3 0.0021 17.5 1.6 2.8 1 1 0 1 1 1 1 SAP domain HeH PF12949.2 EME32567.1 - 0.014 14.8 1.7 0.088 12.3 1.1 2.4 1 1 0 1 1 1 0 HeH/LEM domain Endonuc-dimeris PF09124.5 EME32567.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.9 2 1 1 3 3 3 0 T4 recombination endonuclease VII, dimerisation Asp PF00026.18 EME32568.1 - 1.8e-38 132.5 0.4 2.7e-38 132.0 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EME32568.1 - 5.7e-13 48.7 0.0 1.3e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EME32568.1 - 0.021 15.3 0.1 0.73 10.3 0.0 3.1 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 EME32568.1 - 0.08 12.7 0.7 0.28 11.0 0.1 2.3 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Thymidylat_synt PF00303.14 EME32569.1 - 4e-116 386.7 0.0 5e-116 386.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 EME32569.1 - 1.8e-38 131.6 0.0 6.4e-38 129.8 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase Flu_NS2 PF00601.14 EME32569.1 - 0.033 14.3 0.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) AAA PF00004.24 EME32570.1 - 2.5e-15 56.8 0.0 4.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EME32570.1 - 1.7e-13 50.5 0.1 1e-11 44.7 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EME32570.1 - 1.9e-08 34.1 0.5 8.6e-08 32.0 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EME32570.1 - 1.2e-06 28.7 0.0 3.3e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EME32570.1 - 9.7e-06 24.5 0.1 0.0022 16.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EME32570.1 - 1e-05 25.6 0.0 0.00011 22.1 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EME32570.1 - 9.8e-05 21.5 0.0 0.00034 19.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME32570.1 - 0.00022 21.1 0.0 0.00058 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EME32570.1 - 0.00051 19.6 0.0 0.002 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EME32570.1 - 0.0018 17.5 0.0 0.037 13.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EME32570.1 - 0.004 16.1 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EME32570.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EME32570.1 - 0.0074 15.7 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME32570.1 - 0.0096 15.6 0.0 0.042 13.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME32570.1 - 0.013 16.3 0.0 0.036 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EME32570.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 EME32570.1 - 0.022 13.4 0.0 0.06 12.0 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_24 PF13479.1 EME32570.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME32570.1 - 0.032 14.3 0.0 0.18 11.9 0.0 2.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 EME32570.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EME32570.1 - 0.17 10.6 0.0 6.2 5.5 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain DUF1767 PF08585.7 EME32571.1 - 0.0073 16.5 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) API5 PF05918.6 EME32571.1 - 0.011 14.2 3.2 0.018 13.5 2.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Dehyd-heme_bind PF09098.5 EME32571.1 - 0.094 12.1 2.5 0.45 9.9 0.3 2.3 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding DUF1223 PF06764.6 EME32571.1 - 0.18 11.6 3.5 0.38 10.5 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF1767 PF08585.7 EME32572.1 - 0.0073 16.5 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) AMP-binding PF00501.23 EME32573.1 - 7.1e-76 255.2 0.0 1e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Vir_act_alpha_C PF10400.4 EME32573.1 - 0.014 15.7 0.3 0.049 14.0 0.1 2.0 2 0 0 2 2 2 0 Virulence activator alpha C-term Not3 PF04065.10 EME32573.1 - 0.036 13.3 0.3 0.077 12.2 0.2 1.5 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AMP-binding_C PF13193.1 EME32573.1 - 0.16 12.8 0.0 0.55 11.2 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MBOAT PF03062.14 EME32574.1 - 6.6e-32 110.9 15.7 6.6e-32 110.9 10.9 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 EME32575.1 - 1.4e-33 116.4 14.8 1.4e-33 116.4 10.3 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF106 PF01956.11 EME32576.1 - 0.0023 17.4 0.1 0.0029 17.1 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ADIP PF11559.3 EME32576.1 - 0.0059 16.5 3.1 0.0089 15.9 2.1 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DSRB PF10781.4 EME32576.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Dextransucrase DSRB MscS_porin PF12795.2 EME32576.1 - 0.023 14.0 0.7 0.03 13.6 0.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HMA PF00403.21 EME32576.1 - 0.029 14.5 0.1 0.067 13.3 0.0 1.7 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF2681 PF10883.3 EME32576.1 - 0.046 13.9 0.2 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) tRNA-synt_2c PF01411.14 EME32577.1 - 2.5e-205 682.9 0.3 5.7e-205 681.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EME32577.1 - 1.3e-13 50.5 0.1 2.9e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EME32577.1 - 5.2e-05 22.8 0.1 0.00016 21.3 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Peptidase_S49_N PF08496.5 EME32577.1 - 0.2 11.4 5.3 0.39 10.5 3.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EBP PF05241.7 EME32578.1 - 9.3e-17 60.6 0.8 1.7e-16 59.7 0.5 1.4 1 0 0 1 1 1 1 Emopamil binding protein HA2 PF04408.18 EME32578.1 - 3.8e-11 42.8 0.1 7.8e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EME32578.1 - 1.5e-06 28.0 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold CCT PF06203.9 EME32579.1 - 1.1e-11 44.1 10.7 1.1e-11 44.1 7.4 1.7 2 0 0 2 2 2 1 CCT motif RtcB PF01139.12 EME32580.1 - 2.6e-146 487.9 0.0 2.8e-146 487.8 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cyclin PF08613.6 EME32581.1 - 5.6e-30 104.7 2.1 5.6e-30 104.7 1.5 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EME32581.1 - 6.4e-11 41.9 0.6 9.2e-11 41.4 0.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Beta-Casp PF10996.3 EME32582.1 - 1.7e-16 60.2 0.0 2.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EME32582.1 - 8.7e-14 51.6 0.7 6.8e-13 48.7 0.5 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME32582.1 - 1.2e-09 38.0 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.10 EME32582.1 - 0.097 11.5 0.1 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Bestrophin PF01062.16 EME32583.1 - 5e-48 163.5 4.2 6.6e-48 163.1 2.9 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF599 PF04654.7 EME32583.1 - 0.023 13.8 0.1 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF599 TF_Zn_Ribbon PF08271.7 EME32584.1 - 0.011 14.9 0.1 0.029 13.7 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-IS66 PF13005.2 EME32584.1 - 0.91 9.5 5.2 0.12 12.3 0.6 1.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 NAD_kinase PF01513.16 EME32585.1 - 8.4e-58 195.3 0.0 1.1e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EME32585.1 - 0.0027 17.1 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cpn60_TCP1 PF00118.19 EME32588.1 - 3.2e-152 507.5 5.0 3.9e-152 507.2 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Thioredox_DsbH PF03190.10 EME32589.1 - 2.5e-71 238.6 0.1 4.7e-71 237.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EME32589.1 - 7.1e-13 48.3 0.0 1.9e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME32589.1 - 7.6e-05 22.8 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 EME32589.1 - 0.00037 19.6 5.8 0.022 13.8 0.0 3.6 3 1 1 4 4 4 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EME32589.1 - 0.0012 18.1 9.1 0.32 10.2 0.1 4.9 5 1 1 6 6 6 2 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.6 EME32589.1 - 0.0024 16.9 0.5 1.1 8.2 0.0 3.1 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 EME32589.1 - 0.0048 15.2 1.7 0.055 11.7 0.2 2.1 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 EME32590.1 - 1.4e-29 100.8 17.0 2e-07 30.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EME32590.1 - 7.8e-24 83.5 11.2 1.3e-23 82.7 7.8 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EME32590.1 - 0.00031 20.5 0.0 0.047 13.4 0.0 3.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Peptidase_M16_C PF05193.16 EME32591.1 - 8.6e-37 126.5 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME32591.1 - 3.6e-36 124.1 0.7 5.8e-35 120.2 0.1 2.9 3 1 0 3 3 3 1 Insulinase (Peptidase family M16) HTH_Tnp_Mu_1 PF02316.11 EME32591.1 - 0.033 13.9 1.6 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Mu DNA-binding domain Arf PF00025.16 EME32592.1 - 1.9e-45 154.2 0.0 2.1e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME32592.1 - 5.4e-23 81.1 0.0 6.3e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME32592.1 - 1.1e-11 45.2 0.0 5.6e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME32592.1 - 1.7e-09 37.6 0.1 7.5e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME32592.1 - 8e-08 31.9 0.0 5.1e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EME32592.1 - 1e-07 31.0 0.3 1.9e-06 26.8 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.5 EME32592.1 - 1.7e-07 30.6 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME32592.1 - 4.5e-07 29.2 0.0 5.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 EME32592.1 - 0.028 14.1 0.2 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 EME32592.1 - 0.043 13.1 2.1 0.71 9.1 1.5 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EME32592.1 - 0.054 13.3 0.0 1.6 8.4 0.0 2.5 1 1 1 3 3 3 0 Dynamin family DUF1580 PF07618.6 EME32592.1 - 0.062 12.6 1.6 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) ABC_tran PF00005.22 EME32592.1 - 0.097 12.9 0.1 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EME32592.1 - 0.11 12.0 0.0 2.7 7.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 EME32593.1 - 4.1e-46 156.3 0.1 5.2e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME32593.1 - 6.6e-23 80.8 0.0 7.8e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME32593.1 - 1.3e-11 44.9 0.0 6.7e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME32593.1 - 2.3e-09 37.2 0.1 8.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME32593.1 - 1e-07 31.5 0.0 6e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EME32593.1 - 1.2e-07 30.7 0.3 2.3e-06 26.5 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.5 EME32593.1 - 2e-07 30.3 0.0 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME32593.1 - 5.1e-07 29.0 0.0 6.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 EME32593.1 - 0.034 13.8 0.2 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 EME32593.1 - 0.046 13.0 1.9 0.71 9.1 1.3 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 EME32593.1 - 0.053 13.5 0.2 8 6.4 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EME32593.1 - 0.068 12.9 0.1 1.8 8.3 0.0 2.5 2 1 1 3 3 3 0 Dynamin family DUF1580 PF07618.6 EME32593.1 - 0.073 12.4 1.6 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) ATP_bind_1 PF03029.12 EME32593.1 - 0.14 11.6 0.0 3.1 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EME32593.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.8 1 1 0 1 1 1 0 ABC transporter DUF3591 PF12157.3 EME32594.1 - 3.4e-35 121.3 0.0 7.2e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EME32594.1 - 6.4e-14 51.6 0.1 5.3e-13 48.7 0.1 2.4 2 0 0 2 2 2 1 Bromodomain DUF3591 PF12157.3 EME32595.1 - 3.5e-35 121.2 0.0 7.3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EME32595.1 - 6.6e-14 51.5 0.1 5.3e-13 48.6 0.1 2.4 2 0 0 2 2 2 1 Bromodomain SSXT PF05030.7 EME32596.1 - 5.7e-18 64.2 0.2 2.9e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Myb_DNA-binding PF00249.26 EME32596.1 - 2e-13 50.1 0.1 4.8e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32596.1 - 1.5e-06 28.2 0.3 3.2e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1713 PF08213.6 EME32597.1 - 6.8e-07 28.7 19.6 1.3e-06 27.8 13.6 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Neurexophilin PF06312.7 EME32597.1 - 0.09 12.0 0.2 0.26 10.4 0.0 1.6 1 1 1 2 2 2 0 Neurexophilin mRNA_cap_enzyme PF01331.14 EME32598.1 - 7.1e-31 107.3 0.0 2.8e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EME32598.1 - 4.6e-18 65.4 0.0 7.8e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DUF663 PF04950.7 EME32599.1 - 1.1e-81 274.0 7.7 5.5e-63 212.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 EME32599.1 - 7.7e-11 41.3 0.0 1.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain NAD_binding_10 PF13460.1 EME32599.1 - 0.22 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding WD40 PF00400.27 EME32600.1 - 1.6e-30 103.8 12.7 2.9e-13 49.1 0.2 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EME32600.1 - 0.033 13.9 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RF-1 PF00472.15 EME32601.1 - 6.6e-28 96.7 4.8 1.2e-27 95.9 3.3 1.4 1 0 0 1 1 1 1 RF-1 domain DUF4201 PF13870.1 EME32601.1 - 2.1 7.7 14.7 0.25 10.7 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_2 PF07724.9 EME32602.1 - 8e-54 182.1 0.0 6.4e-52 175.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EME32602.1 - 4.5e-28 98.0 0.0 7.9e-14 51.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EME32602.1 - 1.2e-21 76.3 3.2 1.8e-21 75.8 0.4 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EME32602.1 - 4.2e-20 71.4 2.9 2e-11 43.6 0.3 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EME32602.1 - 2.2e-19 69.5 1.6 1.4e-12 47.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME32602.1 - 1.2e-17 64.4 4.5 1e-05 25.6 0.0 4.7 4 1 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 EME32602.1 - 1.9e-10 40.9 0.0 0.00017 21.7 0.0 4.0 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EME32602.1 - 2e-09 37.0 0.0 0.00077 18.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EME32602.1 - 1.6e-08 34.1 0.0 1.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EME32602.1 - 2.7e-08 33.7 0.0 0.0011 18.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EME32602.1 - 7e-08 33.3 6.7 0.0033 18.2 0.0 4.6 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EME32602.1 - 6.2e-07 29.3 3.9 0.047 13.3 0.0 4.3 4 1 1 5 5 3 2 Archaeal ATPase AAA_18 PF13238.1 EME32602.1 - 7.7e-07 29.4 3.0 0.023 15.0 0.0 3.6 4 0 0 4 4 2 2 AAA domain Zeta_toxin PF06414.7 EME32602.1 - 5.5e-06 25.6 0.0 0.00049 19.2 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EME32602.1 - 7.2e-06 25.6 0.4 0.18 11.5 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EME32602.1 - 7.3e-06 25.2 0.6 0.81 8.8 0.1 4.3 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EME32602.1 - 1.5e-05 24.1 1.4 0.012 14.6 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EME32602.1 - 8.2e-05 22.3 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EME32602.1 - 8.7e-05 22.5 0.0 0.44 10.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EME32602.1 - 9e-05 21.9 0.0 0.48 9.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EME32602.1 - 0.00012 22.2 0.0 0.23 11.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase T2SE PF00437.15 EME32602.1 - 0.00054 18.9 0.0 0.0058 15.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DNA_pol3_delta2 PF13177.1 EME32602.1 - 0.0013 18.3 0.0 0.011 15.4 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EME32602.1 - 0.0016 18.0 0.2 0.73 9.4 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME32602.1 - 0.002 17.9 0.0 0.48 10.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EME32602.1 - 0.0024 17.5 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EME32602.1 - 0.0033 16.6 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME32602.1 - 0.0034 17.6 0.1 0.36 11.1 0.0 3.3 3 1 0 3 3 2 1 ABC transporter AAA_29 PF13555.1 EME32602.1 - 0.0044 16.5 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EME32602.1 - 0.0047 16.4 0.0 0.38 10.1 0.0 3.4 2 1 0 3 3 3 1 AAA-like domain AAA_24 PF13479.1 EME32602.1 - 0.0051 16.4 0.0 1 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EME32602.1 - 0.0061 16.3 0.3 0.27 11.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 UPF0079 PF02367.12 EME32602.1 - 0.0062 16.1 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 EME32602.1 - 0.0063 15.9 0.0 0.15 11.4 0.0 2.9 3 0 0 3 3 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EME32602.1 - 0.0083 15.8 0.0 7.1 6.3 0.0 3.1 3 0 0 3 3 2 0 NTPase Miro PF08477.8 EME32602.1 - 0.0085 16.5 0.0 0.79 10.2 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein Torsin PF06309.6 EME32602.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 1 0 Torsin SRP54 PF00448.17 EME32602.1 - 0.025 14.0 0.4 1.9 7.8 0.0 3.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain DUF1192 PF06698.6 EME32602.1 - 0.028 14.2 12.9 0.023 14.5 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) AAA_23 PF13476.1 EME32602.1 - 0.031 14.6 12.0 0.36 11.1 0.0 3.9 3 1 0 3 3 2 0 AAA domain PhoH PF02562.11 EME32602.1 - 0.045 12.9 0.0 0.6 9.3 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EME32602.1 - 0.047 13.5 0.0 1.2 8.9 0.0 3.0 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit Ras PF00071.17 EME32602.1 - 0.11 11.8 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 Ras family EMP24_GP25L PF01105.19 EME32602.1 - 0.12 12.0 0.7 0.31 10.7 0.5 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD UPF0184 PF03670.8 EME32602.1 - 0.2 11.8 3.3 1.5 9.0 0.2 3.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_6 PF12774.2 EME32602.1 - 0.21 11.0 0.0 1.4 8.3 0.0 2.2 1 1 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 ADIP PF11559.3 EME32602.1 - 0.35 10.7 9.2 0.24 11.2 4.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 EME32602.1 - 0.57 10.4 5.2 0.93 9.7 0.1 3.6 4 0 0 4 4 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EME32602.1 - 0.87 9.1 10.8 3.1 7.3 7.5 1.8 1 1 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 EME32602.1 - 0.9 9.8 7.0 0.22 11.8 0.9 3.0 2 1 1 3 3 1 0 Snapin/Pallidin Spc7 PF08317.6 EME32602.1 - 1.8 7.1 9.9 3.5 6.2 6.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Aminotran_4 PF01063.14 EME32603.1 - 4.5e-25 88.4 0.0 6.1e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Methyltransf_10 PF05971.7 EME32604.1 - 1.6e-62 211.3 0.2 9.3e-61 205.5 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EME32604.1 - 1.7e-06 28.0 0.0 3.5e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME32604.1 - 2.4e-06 27.0 0.0 3.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EME32604.1 - 0.0043 17.6 0.0 0.0063 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF633 PF04816.7 EME32604.1 - 0.0073 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF633) PrmA PF06325.8 EME32604.1 - 0.0081 15.3 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EME32604.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EME32604.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Spo7 PF03907.8 EME32605.1 - 6.6e-07 29.1 3.8 9e-07 28.7 2.6 1.1 1 0 0 1 1 1 1 Spo7-like protein Aldo_ket_red PF00248.16 EME32606.1 - 1.1e-58 198.3 0.0 1.2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abp2 PF09441.5 EME32607.1 - 0.015 15.2 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 ARS binding protein 2 TRAM_LAG1_CLN8 PF03798.11 EME32608.1 - 4e-27 95.0 19.8 4e-27 95.0 13.7 1.7 2 0 0 2 2 2 1 TLC domain Glycos_transf_2 PF00535.21 EME32609.1 - 9.2e-27 93.7 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME32609.1 - 2.4e-10 40.6 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EME32609.1 - 0.00055 19.1 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 S10_plectin PF03501.10 EME32609.1 - 0.17 11.7 0.7 1.6 8.6 0.1 2.6 2 1 1 3 3 3 0 Plectin/S10 domain Patatin PF01734.17 EME32610.1 - 1.7e-31 109.7 1.3 6.8e-31 107.7 0.0 2.6 3 0 0 3 3 3 1 Patatin-like phospholipase Arm PF00514.18 EME32610.1 - 0.00042 20.0 0.3 0.00093 18.9 0.2 1.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat WD40 PF00400.27 EME32611.1 - 3.8e-58 191.4 31.3 5.7e-10 38.6 1.5 10.7 11 0 0 11 11 11 10 WD domain, G-beta repeat Nup160 PF11715.3 EME32611.1 - 2.3e-07 29.3 8.2 0.0029 15.8 0.1 4.3 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME32611.1 - 1.3e-05 24.1 6.7 0.055 12.2 0.0 4.7 2 2 1 4 4 4 3 Nup133 N terminal like DUF4221 PF13970.1 EME32611.1 - 0.0011 18.3 2.8 0.0065 15.8 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4221) Cytochrom_D1 PF02239.11 EME32611.1 - 0.0062 14.8 0.1 0.023 13.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain Hira PF07569.6 EME32611.1 - 0.017 14.3 0.0 0.77 8.9 0.0 2.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Utp13 PF08625.6 EME32612.1 - 7.9e-26 90.3 1.0 1.4e-25 89.5 0.1 1.7 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain LOH1CR12 PF10158.4 EME32612.1 - 0.0025 17.5 0.1 0.0061 16.3 0.1 1.6 1 0 0 1 1 1 1 Tumour suppressor protein Utp12 PF04003.7 EME32612.1 - 0.0073 16.1 2.3 0.0087 15.9 0.3 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family F-box-like PF12937.2 EME32612.1 - 0.056 13.1 2.0 0.81 9.4 0.8 2.8 2 1 1 3 3 3 0 F-box-like S6PP PF05116.8 EME32613.1 - 2.7e-35 121.8 0.0 6.6e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Glycos_transf_1 PF00534.15 EME32613.1 - 3.8e-25 88.2 0.0 6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.14 EME32613.1 - 4.1e-09 34.9 0.1 7.4e-09 34.1 0.1 1.4 1 1 0 1 1 1 1 Sucrose synthase Hydrolase_3 PF08282.7 EME32613.1 - 3.8e-06 26.6 0.0 0.00012 21.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.1 EME32613.1 - 1.9e-05 24.8 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EME32613.1 - 3.9e-05 23.8 0.0 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME32613.1 - 0.00012 22.3 0.0 0.00025 21.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EME32613.1 - 0.12 12.1 0.1 35 4.0 0.0 3.4 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Pkinase_Tyr PF07714.12 EME32614.1 - 1.4e-55 188.1 0.0 9.6e-54 182.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME32614.1 - 1.2e-51 175.4 0.0 1.9e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EME32614.1 - 1.3e-33 115.1 0.0 1.6e-16 60.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME32614.1 - 9.5e-28 94.6 0.0 4.5e-10 38.8 0.0 5.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EME32614.1 - 8.2e-26 89.4 0.4 1.8e-13 50.2 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME32614.1 - 5.6e-23 80.8 0.1 9e-09 35.6 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME32614.1 - 2.2e-19 67.6 0.0 8.7e-07 28.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat EF-hand_7 PF13499.1 EME32614.1 - 1.2e-05 25.3 0.8 3.8e-05 23.7 0.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EME32614.1 - 0.0018 18.0 0.5 1.2 9.1 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EME32614.1 - 0.006 16.1 2.4 0.16 11.5 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair APH PF01636.18 EME32614.1 - 0.033 13.9 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2205 PF10224.4 EME32615.1 - 0.0094 15.4 2.9 0.034 13.7 2.0 1.9 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EME32615.1 - 0.017 15.4 3.3 0.017 15.4 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Herpes_BLRF2 PF05812.7 EME32615.1 - 0.025 14.3 4.3 0.057 13.2 3.0 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DivIC PF04977.10 EME32615.1 - 0.2 11.1 8.9 0.05 13.0 3.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EME32615.1 - 1.7 9.0 11.7 1.1 9.6 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 EME32615.1 - 3.1 7.5 10.2 0.21 11.3 3.2 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper KLRAQ PF10205.4 EME32615.1 - 8.4 6.5 13.0 0.11 12.5 2.3 2.8 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein zf-C4 PF00105.13 EME32618.1 - 0.046 13.9 0.2 0.058 13.6 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Arch_ATPase PF01637.13 EME32620.1 - 0.00074 19.2 0.0 0.0026 17.5 0.0 1.9 2 1 0 2 2 2 1 Archaeal ATPase DUF1654 PF07867.6 EME32620.1 - 0.17 11.2 0.0 0.48 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) SAM_1 PF00536.25 EME32621.1 - 0.0012 19.0 0.1 0.003 17.6 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PPR PF01535.15 EME32621.1 - 0.16 11.9 0.3 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 PPR repeat S-AdoMet_synt_C PF02773.11 EME32622.1 - 5.1e-74 246.5 0.1 7.7e-74 245.9 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EME32622.1 - 4.1e-48 162.2 0.0 7.2e-48 161.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EME32622.1 - 1.6e-41 140.5 0.2 3.1e-41 139.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Pro_isomerase PF00160.16 EME32623.1 - 1.2e-43 149.0 0.0 1.7e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EME32623.1 - 1.5e-11 43.7 0.0 2.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32623.1 - 3e-08 33.5 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME32623.1 - 8.3e-08 31.9 0.1 2.2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_2 PF07647.12 EME32625.1 - 0.066 13.0 0.1 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Somatostatin PF03002.10 EME32626.1 - 0.6 9.7 3.5 1.1 8.9 2.5 1.4 1 0 0 1 1 1 0 Somatostatin/Cortistatin family FmdA_AmdA PF03069.10 EME32628.1 - 3.2e-149 496.6 0.0 3.8e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family DUF4568 PF15132.1 EME32628.1 - 0.084 12.0 0.6 0.13 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) SSF PF00474.12 EME32629.1 - 4.3e-16 58.5 26.1 4.3e-16 58.5 18.1 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family zf-C3HC4_3 PF13920.1 EME32630.1 - 4.1e-08 32.7 14.3 1.1e-07 31.3 9.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME32630.1 - 0.89 9.2 18.2 2.9 7.6 12.6 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aa_trans PF01490.13 EME32631.1 - 7.6e-14 50.9 11.6 8.9e-14 50.7 8.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YlaH PF14036.1 EME32631.1 - 0.057 13.5 0.9 0.057 13.5 0.6 2.4 2 0 0 2 2 2 0 YlaH-like protein DUF2207 PF09972.4 EME32631.1 - 3.3 6.1 8.5 0.61 8.6 3.2 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Cation_ATPase_C PF00689.16 EME32631.1 - 4.8 6.6 11.4 32 3.9 7.5 2.1 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Aa_trans PF01490.13 EME32632.1 - 5.9e-35 120.5 44.0 7e-35 120.2 30.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAD_porph PF04371.10 EME32633.1 - 1.8e-122 408.4 0.0 2.1e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase MIP PF00230.15 EME32635.1 - 2.3e-48 164.6 7.4 2.8e-48 164.3 5.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PsbP PF01789.11 EME32636.1 - 9.4e-23 80.5 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 PsbP DUF1795 PF08786.6 EME32636.1 - 0.077 12.8 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1795) LSM PF01423.17 EME32637.1 - 5.4e-17 61.0 0.1 7.2e-17 60.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain UCH PF00443.24 EME32638.1 - 9e-44 149.5 0.7 1.2e-43 149.2 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME32638.1 - 1.9e-13 50.5 0.7 2.9e-13 49.9 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EME32638.1 - 0.00021 20.5 0.1 0.00091 18.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EME32638.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like OTCace_N PF02729.16 EME32639.1 - 3.4e-43 146.7 0.0 5.2e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EME32639.1 - 8.8e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace PF00185.19 EME32640.1 - 3.1e-48 163.6 0.0 4.5e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EME32640.1 - 5.5e-43 146.0 0.0 1.3e-42 144.8 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_31 PF01055.21 EME32641.1 - 8.7e-102 341.2 2.7 1.1e-101 340.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME32641.1 - 1.3e-19 69.8 0.1 3.6e-19 68.3 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like RNase_HII PF01351.13 EME32642.1 - 8.3e-43 146.3 0.0 1.1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Methyltransf_31 PF13847.1 EME32642.1 - 0.0026 17.3 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain DUF1515 PF07439.6 EME32642.1 - 0.014 15.1 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Pkinase PF00069.20 EME32644.1 - 6.6e-69 231.9 0.0 1.3e-68 231.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32644.1 - 1.3e-40 139.1 0.0 2.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME32644.1 - 0.00014 20.9 0.0 0.00032 19.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like SWIB PF02201.13 EME32645.1 - 3.4e-44 148.4 6.7 5e-22 77.3 0.4 2.7 3 0 0 3 3 3 2 SWIB/MDM2 domain GSP_synth PF03738.9 EME32645.1 - 0.027 14.7 1.1 3.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Glutathionylspermidine synthase preATP-grasp rve_2 PF13333.1 EME32645.1 - 0.45 10.6 2.4 0.48 10.5 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain PITH PF06201.8 EME32646.1 - 4.8e-38 130.3 0.1 5.8e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 PITH domain Herpes_UL69 PF05459.7 EME32646.1 - 0.039 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family YgbB PF02542.11 EME32647.1 - 2.6e-57 193.0 0.0 5.3e-57 192.0 0.0 1.5 1 0 0 1 1 1 1 YgbB family PRA-PH PF01503.12 EME32647.1 - 8.2e-13 48.4 0.0 2.6e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EME32647.1 - 0.06 13.2 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain PrkA PF06798.7 EME32647.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Pep_deformylase PF01327.16 EME32648.1 - 2.9e-51 172.9 0.0 3.6e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase POP1 PF06978.6 EME32649.1 - 9.2e-31 106.9 7.4 2.2e-18 66.5 1.6 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EME32649.1 - 5.2e-14 51.8 0.0 1.6e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain HAD_2 PF13419.1 EME32650.1 - 2.4e-09 37.6 0.0 3.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME32650.1 - 3.3e-08 33.1 0.0 7.2e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EME32650.1 - 1.7e-07 31.6 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME32650.1 - 3.8e-07 30.7 0.1 1.4e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EME32650.1 - 0.0079 15.5 0.0 4.3 6.6 0.0 2.6 2 1 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.7 EME32650.1 - 0.018 14.6 0.0 0.91 9.0 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME32650.1 - 0.032 14.1 0.0 12 5.8 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.6 EME32651.1 - 8.3e-09 35.0 1.5 8.3e-09 35.0 1.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain PBC PF03792.8 EME32651.1 - 0.0038 16.9 0.1 0.005 16.5 0.1 1.3 1 0 0 1 1 1 1 PBC domain Homeobox PF00046.24 EME32651.1 - 0.0095 15.5 0.9 0.033 13.8 0.1 2.1 2 0 0 2 2 2 1 Homeobox domain DUF3523 PF12037.3 EME32651.1 - 0.095 11.6 0.3 0.17 10.8 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) CIA30 PF08547.7 EME32652.1 - 1.4e-42 145.2 0.0 4.1e-42 143.7 0.0 1.8 2 0 0 2 2 2 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.1 EME32652.1 - 5.5e-21 75.4 0.0 3.7e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding GST_N_3 PF13417.1 EME32652.1 - 1.2e-14 54.2 0.0 3.5e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME32652.1 - 6.2e-12 45.5 0.2 3e-11 43.3 0.0 2.4 3 0 0 3 3 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME32652.1 - 8.5e-12 44.9 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NmrA PF05368.8 EME32652.1 - 2.8e-11 43.1 0.0 5.4e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family GST_C_2 PF13410.1 EME32652.1 - 0.00044 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 EME32652.1 - 0.0018 17.7 0.2 0.0072 15.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GST_C PF00043.20 EME32652.1 - 0.0024 17.8 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RmlD_sub_bind PF04321.12 EME32652.1 - 0.0036 16.2 0.0 0.58 9.0 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain GST_C_3 PF14497.1 EME32652.1 - 0.0083 16.5 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.14 EME32652.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EME32652.1 - 0.022 14.2 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 EME32652.1 - 0.029 13.2 0.1 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 EME32652.1 - 0.034 14.0 0.1 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 EME32652.1 - 0.098 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EME32652.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME32652.1 - 0.31 10.9 0.7 0.55 10.1 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DNA_topoisoIV PF00521.15 EME32653.1 - 5.3e-126 420.9 0.0 5.3e-126 420.9 0.0 2.4 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EME32653.1 - 2.1e-33 114.9 0.2 2.1e-33 114.9 0.1 2.5 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EME32653.1 - 2.9e-14 52.8 0.0 2e-13 50.1 0.0 2.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EME32653.1 - 7.7e-11 41.7 0.0 2.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nuf2 PF03800.9 EME32654.1 - 9.8e-46 155.3 0.3 9.8e-46 155.3 0.2 2.6 2 1 1 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EME32654.1 - 0.0027 16.9 7.3 0.16 11.1 0.4 3.0 1 1 2 3 3 3 3 Reovirus sigma C capsid protein DUF4200 PF13863.1 EME32654.1 - 0.034 14.0 62.0 0.26 11.2 12.5 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 EME32654.1 - 0.035 12.7 50.7 1.8 7.1 13.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.4 EME32654.1 - 0.052 12.2 46.0 0.31 9.7 7.2 3.4 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 ADIP PF11559.3 EME32654.1 - 0.058 13.3 52.6 0.022 14.6 8.0 4.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding SMC_hinge PF06470.8 EME32654.1 - 0.059 13.3 0.5 7.5 6.5 0.1 2.7 3 0 0 3 3 2 0 SMC proteins Flexible Hinge Domain DUF3584 PF12128.3 EME32654.1 - 0.12 9.6 48.2 0.4 7.9 9.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 EME32654.1 - 0.26 10.7 52.4 0.082 12.3 7.5 3.9 1 1 1 3 3 3 0 Intermediate filament protein DUF1515 PF07439.6 EME32654.1 - 0.78 9.5 24.0 0.36 10.6 1.7 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) APG6 PF04111.7 EME32654.1 - 1.3 8.0 55.9 0.52 9.3 11.3 3.3 1 1 1 3 3 3 0 Autophagy protein Apg6 PilJ PF13675.1 EME32654.1 - 1.9 8.8 20.0 0.73 10.1 2.0 4.4 2 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-F_leu_zip PF10473.4 EME32654.1 - 2.6 7.9 58.5 2.8 7.7 5.0 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 EME32654.1 - 3.6 5.7 47.8 0.2 9.8 18.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) FliJ PF02050.11 EME32654.1 - 3.6 7.6 45.6 2.2 8.3 11.6 4.3 1 1 1 3 3 3 0 Flagellar FliJ protein MCPsignal PF00015.16 EME32654.1 - 4 6.9 23.4 0.72 9.3 3.5 3.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 EME32654.1 - 4.3 6.5 37.6 6.4 5.9 6.0 3.8 1 1 1 3 3 3 0 Laminin Domain I WXG100 PF06013.7 EME32654.1 - 5 7.1 19.6 12 5.9 0.1 5.9 4 2 3 7 7 7 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.7 EME32654.1 - 6.7 6.4 55.6 38 4.0 2.2 4.7 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein AAA_27 PF13514.1 EME32654.1 - 7.1 4.1 42.6 8.5 3.9 7.8 2.0 1 1 1 2 2 2 0 AAA domain HlyD PF00529.15 EME32654.1 - 7.5 5.7 28.7 1.6 7.9 7.2 2.3 1 1 1 2 2 2 0 HlyD family secretion protein TMF_DNA_bd PF12329.3 EME32654.1 - 9.7 6.0 47.0 2 8.2 4.3 5.7 3 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding PGK PF00162.14 EME32655.1 - 3.3e-161 536.1 0.0 3.7e-161 535.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ribosomal_L32e PF01655.13 EME32656.1 - 3.4e-50 168.6 1.7 4.1e-50 168.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Sec39 PF08314.6 EME32657.1 - 0.028 12.3 0.1 0.034 12.0 0.1 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Cornichon PF03311.9 EME32658.1 - 2e-37 128.1 11.4 2.5e-37 127.8 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein DUF898 PF05987.8 EME32658.1 - 0.21 10.4 6.3 0.26 10.1 4.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Fer4_14 PF13394.1 EME32659.1 - 5e-18 65.2 0.2 3.7e-17 62.4 0.1 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 EME32659.1 - 1e-11 45.2 0.0 1.8e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EME32659.1 - 1.1e-11 45.0 0.0 2.8e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain zf-CHCC PF10276.4 EME32659.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger domain SAM_2 PF07647.12 EME32659.1 - 0.098 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1654 PF07867.6 EME32660.1 - 0.1 11.9 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) RNA_pol_Rpc34 PF05158.7 EME32664.1 - 1.8e-74 250.9 2.8 7.6e-72 242.2 2.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EME32664.1 - 1.6e-05 24.6 0.2 0.00017 21.3 0.2 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.14 EME32664.1 - 0.0046 16.6 0.4 0.2 11.3 0.1 3.0 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Stn1_C PF12659.2 EME32664.1 - 0.04 13.7 0.4 0.17 11.7 0.0 2.1 3 0 0 3 3 3 0 Telomere capping C-terminal wHTH AIG2 PF06094.7 EME32666.1 - 5.7e-10 39.6 0.2 7.6e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 AIG2-like family Acyltransferase PF01553.16 EME32667.1 - 1.4e-18 66.5 0.0 3.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase S1 PF00575.18 EME32668.1 - 4e-33 113.3 2.6 2.7e-15 56.1 0.4 3.3 3 0 0 3 3 3 3 S1 RNA binding domain DUF2110 PF09883.4 EME32668.1 - 0.01 15.4 0.0 0.92 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) LUC7 PF03194.10 EME32669.1 - 7.4e-59 199.3 7.6 7e-36 124.0 0.3 2.4 2 1 0 2 2 2 2 LUC7 N_terminus WW PF00397.21 EME32669.1 - 9.3e-08 31.7 1.7 2.7e-07 30.3 1.2 1.8 1 0 0 1 1 1 1 WW domain CIA30 PF08547.7 EME32670.1 - 3e-29 101.9 0.0 3.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EME32670.1 - 0.0015 18.2 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) DUF3471 PF11954.3 EME32670.1 - 0.044 13.6 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Pyridox_oxidase PF01243.15 EME32671.1 - 3.2e-23 81.5 0.0 8.1e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EME32671.1 - 1.5e-16 59.5 4.5 1.7e-16 59.3 1.8 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EME32671.1 - 3.9e-09 36.7 0.1 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M50 PF02163.17 EME32671.1 - 0.69 8.8 4.4 1.3 7.8 3.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 Pyridox_oxidase PF01243.15 EME32672.1 - 3.2e-23 81.5 0.0 8.1e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EME32672.1 - 1.5e-16 59.5 4.5 1.7e-16 59.3 1.8 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EME32672.1 - 3.9e-09 36.7 0.1 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M50 PF02163.17 EME32672.1 - 0.69 8.8 4.4 1.3 7.8 3.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 Grp1_Fun34_YaaH PF01184.14 EME32673.1 - 2.3e-39 134.9 13.8 3e-39 134.4 9.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family cwf18 PF08315.7 EME32674.1 - 1.5e-14 54.5 2.4 1.5e-14 54.5 1.7 1.6 1 1 1 2 2 2 1 cwf18 pre-mRNA splicing factor DUF1564 PF07600.6 EME32674.1 - 0.031 13.6 0.9 0.049 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) ATP-synt_F PF01990.12 EME32674.1 - 0.04 14.3 1.2 0.082 13.3 0.3 1.8 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit Protocadherin PF08374.6 EME32674.1 - 0.077 12.6 3.7 0.091 12.3 2.6 1.1 1 0 0 1 1 1 0 Protocadherin Noggin PF05806.7 EME32674.1 - 0.1 11.8 0.6 0.12 11.6 0.4 1.2 1 0 0 1 1 1 0 Noggin DUF4611 PF15387.1 EME32674.1 - 0.19 11.9 4.2 0.32 11.1 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DnaJ PF00226.26 EME32675.1 - 3.7e-18 65.0 0.6 6.8e-18 64.1 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.8 EME32675.1 - 0.0078 16.5 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Sec23_trunk PF04811.10 EME32677.1 - 8.2e-58 195.6 0.0 1.2e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EME32677.1 - 3.5e-17 62.6 0.2 2.3e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EME32677.1 - 8.2e-15 54.0 1.6 2.3e-14 52.6 1.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EME32677.1 - 4.9e-12 45.1 0.2 9.1e-12 44.3 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF4514 PF14986.1 EME32677.1 - 0.21 11.4 0.5 0.49 10.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Peroxin-3 PF04882.7 EME32678.1 - 5.3e-38 130.8 14.2 1.5e-29 103.0 3.1 2.7 1 1 1 2 2 2 2 Peroxin-3 UTP15_C PF09384.5 EME32681.1 - 1.8e-38 131.5 0.1 2.7e-38 130.9 0.1 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EME32681.1 - 1.4e-27 94.5 8.3 1.9e-07 30.7 0.6 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat GFO_IDH_MocA PF01408.17 EME32682.1 - 1.4e-17 64.3 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME32682.1 - 2.8e-05 23.8 0.0 9.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 EME32682.1 - 9.2e-05 22.8 0.1 0.00034 20.9 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EME32682.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DJ-1_PfpI PF01965.19 EME32683.1 - 1e-29 102.9 0.0 1.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EME32683.1 - 1.3e-14 53.7 0.1 1.7e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_5 PF13507.1 EME32683.1 - 0.037 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF2345 PF10106.4 EME32683.1 - 0.052 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) TPR_5 PF12688.2 EME32683.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat Ldh_1_C PF02866.13 EME32684.1 - 2.9e-37 128.0 0.0 6.1e-37 127.0 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EME32684.1 - 7.4e-34 116.5 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glycos_transf_N PF04413.11 EME32685.1 - 2.8e-29 101.6 0.1 8.8e-28 96.7 0.1 2.2 1 1 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Sugar_tr PF00083.19 EME32686.1 - 1.9e-25 89.3 32.8 4.3e-15 55.2 8.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME32686.1 - 3.7e-08 32.4 45.5 1.4e-05 23.9 16.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-DNA_Pol PF08996.5 EME32687.1 - 0.00085 18.7 0.2 0.00097 18.5 0.1 1.0 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger HAD_2 PF13419.1 EME32688.1 - 8.9e-19 68.3 0.0 1.2e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME32688.1 - 1.3e-09 37.6 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME32688.1 - 1.2e-07 32.3 0.0 3.7e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME32688.1 - 0.0033 17.6 0.1 0.0059 16.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME32689.1 - 1.8e-16 60.8 0.0 4.4e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME32689.1 - 1.4e-09 37.5 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EME32689.1 - 7.9e-07 29.6 0.2 0.00036 21.0 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME32689.1 - 0.067 13.3 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Abi PF02517.11 EME32690.1 - 1.2e-15 57.4 11.0 1.2e-15 57.4 7.6 2.7 1 1 1 2 2 2 1 CAAX protease self-immunity SNAPc_SNAP43 PF09808.4 EME32691.1 - 2.2e-15 56.8 1.2 2.2e-15 56.8 0.8 2.0 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Glycos_transf_2 PF00535.21 EME32692.1 - 1.8e-31 109.0 0.0 2.8e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME32692.1 - 3.5e-13 49.8 0.0 5.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EME32692.1 - 1.6e-07 30.6 0.0 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EME32692.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 FleQ PF06490.6 EME32692.1 - 0.11 12.6 0.0 0.83 9.8 0.0 2.1 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Lyase_1 PF00206.15 EME32693.1 - 3.4e-118 394.3 0.0 4.3e-118 394.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EME32693.1 - 1.2e-24 86.0 0.0 2.8e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Lyase_1 PF00206.15 EME32694.1 - 3.4e-118 394.3 0.0 4.3e-118 394.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EME32694.1 - 1.2e-24 86.0 0.0 2.8e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus DUF673 PF05054.7 EME32695.1 - 0.0085 14.7 0.5 0.01 14.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF673) DUF3635 PF12330.3 EME32695.1 - 0.021 14.9 0.3 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3635) T2SM PF04612.7 EME32695.1 - 0.067 12.9 0.1 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Na_H_Exchanger PF00999.16 EME32696.1 - 5.1e-47 160.2 39.4 5.1e-47 160.2 27.3 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family SHOCT PF09851.4 EME32696.1 - 0.21 11.1 2.5 0.16 11.4 0.2 2.0 2 0 0 2 2 2 0 Short C-terminal domain Gly_transf_sug PF04488.10 EME32697.1 - 1.7e-16 60.4 0.3 9e-16 58.1 0.1 2.3 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EME32697.1 - 0.016 13.6 5.3 0.12 10.8 0.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain TIP49 PF06068.8 EME32698.1 - 9.4e-178 590.9 4.6 1.1e-177 590.6 3.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EME32698.1 - 3.3e-10 40.2 0.4 5.4e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME32698.1 - 1.6e-07 30.6 2.4 8.5e-05 21.7 0.1 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME32698.1 - 5e-07 29.9 0.3 0.047 13.8 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME32698.1 - 8.2e-07 29.1 0.0 0.024 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EME32698.1 - 4.1e-06 26.3 0.2 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME32698.1 - 7.8e-06 25.6 0.3 0.0028 17.3 0.1 3.3 2 1 2 4 4 4 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 EME32698.1 - 3.5e-05 22.8 0.1 7.3e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 EME32698.1 - 0.0002 20.8 0.2 0.19 11.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EME32698.1 - 0.00034 20.2 0.0 0.00068 19.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EME32698.1 - 0.00035 19.7 0.2 0.00076 18.6 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 EME32698.1 - 0.00041 19.5 0.4 0.004 16.3 0.1 2.2 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 EME32698.1 - 0.0016 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EME32698.1 - 0.0018 18.6 0.3 0.0054 17.0 0.1 1.8 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EME32698.1 - 0.0034 16.5 1.3 0.076 12.1 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EME32698.1 - 0.0036 16.3 0.2 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EME32698.1 - 0.0057 16.5 0.1 6.3 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EME32698.1 - 0.012 15.2 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EME32698.1 - 0.015 14.5 0.5 0.039 13.1 0.4 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EME32698.1 - 0.023 14.1 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EME32698.1 - 0.023 14.9 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EME32698.1 - 0.031 13.7 0.3 1.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 EME32698.1 - 0.037 13.6 0.3 0.086 12.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 EME32698.1 - 0.042 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 EME32698.1 - 0.043 13.2 0.3 0.58 9.5 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EME32698.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME32698.1 - 0.086 12.8 0.3 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME32698.1 - 0.11 13.3 0.2 0.59 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain CHCH PF06747.8 EME32699.1 - 3.6e-05 23.5 10.3 0.002 18.0 1.6 2.5 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 EME32699.1 - 0.036 14.0 12.6 1.1 9.3 0.4 3.2 1 1 3 4 4 4 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EME32699.1 - 0.043 13.5 11.9 0.044 13.5 2.8 2.3 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 EME32699.1 - 0.78 9.7 5.0 4.2 7.4 0.1 2.8 1 1 2 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.7 EME32699.1 - 1.4 8.8 6.1 9.5 6.1 2.9 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) SRCR PF00530.13 EME32699.1 - 1.9 8.9 5.4 17 5.8 0.3 2.2 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain UCR_hinge PF02320.11 EME32699.1 - 3.6 7.6 7.5 1.4 8.9 0.2 2.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EME32699.1 - 3.9 7.5 12.6 1.4 9.0 1.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EME32700.1 - 1.4e-05 24.8 5.8 0.011 15.6 0.9 2.6 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EME32700.1 - 0.026 14.2 10.6 0.037 13.8 2.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EME32700.1 - 0.054 13.5 10.1 1.1 9.3 0.3 2.7 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EME32700.1 - 0.62 10.1 12.1 0.19 11.7 1.3 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 EME32700.1 - 0.67 9.8 4.7 1.9 8.3 1.0 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Ndufs5 PF10200.4 EME32700.1 - 1 9.3 4.1 3.5 7.6 0.1 2.3 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UCR_hinge PF02320.11 EME32700.1 - 2.8 7.9 6.9 39 4.2 4.7 2.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Tho2 PF11262.3 EME32701.1 - 1.2e-57 195.2 6.7 1.2e-57 195.2 4.7 2.4 3 0 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EME32701.1 - 3.3e-21 74.8 0.0 8e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit HLH PF00010.21 EME32702.1 - 3.9e-09 36.0 1.6 7.7e-09 35.1 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PPTA PF01239.17 EME32703.1 - 4e-40 133.5 12.7 2e-08 33.2 0.1 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 EME32703.1 - 0.0016 18.7 0.0 0.12 12.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME32703.1 - 0.011 16.3 1.3 7.9 7.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME32703.1 - 0.025 15.2 0.2 2.6 8.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Myosin_head PF00063.16 EME32704.1 - 9.6e-170 565.9 0.0 1.6e-169 565.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 EME32704.1 - 1.3e-18 64.7 63.1 0.00035 19.9 0.6 10.8 9 1 1 10 10 10 7 IQ calmodulin-binding motif DnaJ PF00226.26 EME32704.1 - 7.5e-16 57.6 0.0 2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain AAA_16 PF13191.1 EME32704.1 - 1.6e-07 31.5 0.0 0.006 16.5 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EME32704.1 - 3.6e-05 23.9 0.0 0.085 13.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AIG1 PF04548.11 EME32704.1 - 0.00016 20.8 0.8 0.02 13.9 0.3 3.0 2 1 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EME32704.1 - 0.00061 19.0 0.1 0.031 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME32704.1 - 0.0025 18.1 0.5 0.92 9.8 0.0 2.9 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 EME32704.1 - 0.0026 16.8 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 EME32704.1 - 0.003 17.0 0.2 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EME32704.1 - 0.0034 17.2 1.8 0.0092 15.8 0.6 2.2 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EME32704.1 - 0.0036 16.7 0.0 0.37 10.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Fascin PF06268.8 EME32704.1 - 0.0039 17.2 0.4 3.3 7.8 0.0 4.7 3 2 2 5 5 5 1 Fascin domain DUF815 PF05673.8 EME32704.1 - 0.0043 16.0 0.1 0.045 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EME32704.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME32704.1 - 0.005 17.3 0.9 0.014 15.9 0.1 2.2 2 0 0 2 2 1 1 Miro-like protein AAA_17 PF13207.1 EME32704.1 - 0.0056 17.4 0.0 6.3 7.6 0.0 3.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME32704.1 - 0.018 15.2 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 EME32704.1 - 0.018 14.5 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EME32704.1 - 0.02 14.5 0.0 7.2 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EME32704.1 - 0.02 14.3 1.5 1.3 8.4 0.0 3.0 3 0 0 3 3 2 0 AAA-like domain Septin PF00735.13 EME32704.1 - 0.023 13.7 0.3 0.3 10.0 0.0 2.6 3 0 0 3 3 3 0 Septin AAA_18 PF13238.1 EME32704.1 - 0.04 14.2 0.0 5.7 7.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EME32704.1 - 0.057 13.6 0.0 5.5 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME32704.1 - 0.34 10.5 0.3 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IncA PF04156.9 EME32705.1 - 3e-05 23.6 7.8 4.5e-05 23.1 5.4 1.2 1 0 0 1 1 1 1 IncA protein V_ATPase_I PF01496.14 EME32705.1 - 0.00032 18.7 5.8 0.00043 18.2 4.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DivIC PF04977.10 EME32705.1 - 0.0071 15.8 12.7 0.052 13.0 2.6 2.4 1 1 1 2 2 2 2 Septum formation initiator AAA_13 PF13166.1 EME32705.1 - 0.013 14.0 8.0 0.024 13.1 5.5 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EME32705.1 - 0.024 13.7 8.8 0.034 13.2 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RSN1_TM PF13967.1 EME32705.1 - 0.026 14.1 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Seryl_tRNA_N PF02403.17 EME32705.1 - 0.053 13.5 12.0 0.13 12.2 8.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Nse4_C PF08743.5 EME32705.1 - 0.053 13.5 0.4 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Nse4 C-terminal GAS PF13851.1 EME32705.1 - 0.057 12.6 11.5 0.086 12.0 7.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2935 PF11155.3 EME32705.1 - 0.066 13.3 2.6 0.1 12.7 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) EF-hand_like PF09279.6 EME32705.1 - 0.071 13.1 0.1 0.071 13.1 0.1 1.9 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Selenoprotein_S PF06936.6 EME32705.1 - 0.3 10.6 5.5 0.34 10.4 3.3 1.4 1 1 0 1 1 1 0 Selenoprotein S (SelS) TMPIT PF07851.8 EME32705.1 - 0.88 8.5 5.1 1.3 7.9 3.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.7 EME32705.1 - 2.3 8.0 7.6 6.9 6.4 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YMF19 PF02326.10 EME32705.1 - 2.4 8.7 6.1 1.8 9.1 0.9 2.5 1 1 1 2 2 2 0 Plant ATP synthase F0 Fib_alpha PF08702.5 EME32705.1 - 2.9 8.0 10.0 1.9 8.5 5.6 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4337 PF14235.1 EME32705.1 - 5.5 6.8 8.2 13 5.6 5.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Acyl_transf_1 PF00698.16 EME32706.1 - 5.1e-34 118.0 0.0 6.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain PA28_alpha PF02251.13 EME32706.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Raptor_N PF14538.1 EME32707.1 - 4.3e-69 231.2 0.0 9.7e-69 230.1 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT_2 PF13646.1 EME32707.1 - 1e-07 32.0 0.0 0.18 12.1 0.0 3.9 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EME32707.1 - 4.8e-07 29.3 4.2 0.75 10.0 0.0 5.3 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.15 EME32707.1 - 0.00062 18.2 0.2 0.001 17.5 0.1 1.4 1 0 0 1 1 1 1 Adaptin N terminal region WD40 PF00400.27 EME32707.1 - 0.0046 16.7 11.5 0.039 13.8 0.1 5.4 7 0 0 7 7 7 1 WD domain, G-beta repeat Cnd3 PF12719.2 EME32707.1 - 0.016 14.2 0.2 0.031 13.2 0.1 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Peptidase_C14 PF00656.17 EME32707.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Caspase domain Red1 PF07964.6 EME32707.1 - 0.066 11.3 0.9 0.1 10.7 0.6 1.1 1 0 0 1 1 1 0 Rec10 / Red1 FAD_binding_1 PF00667.15 EME32708.1 - 2.5e-42 144.7 0.4 5.7e-42 143.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EME32708.1 - 2.1e-25 89.3 0.0 4.2e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EME32708.1 - 1.9e-18 67.0 0.0 4.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EME32708.1 - 0.00069 19.6 0.1 0.0041 17.1 0.0 2.3 2 1 0 2 2 2 1 Flavodoxin domain DUF3990 PF13151.1 EME32708.1 - 0.042 13.2 0.0 0.44 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) Transketolase_C PF02780.15 EME32708.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain RhoGAP PF00620.22 EME32709.1 - 1.3e-24 86.4 0.1 2.7e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain EF-hand_4 PF12763.2 EME32709.1 - 2.3e-05 24.0 0.0 7.8e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Creb_binding PF09030.5 EME32709.1 - 0.012 15.8 0.6 0.027 14.6 0.4 1.6 1 0 0 1 1 1 0 Creb binding EF-hand_1 PF00036.27 EME32709.1 - 0.093 12.0 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 EF hand RNA_pol_Rpb2_6 PF00562.23 EME32710.1 - 6.4e-115 383.9 0.0 9.4e-115 383.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME32710.1 - 5e-30 103.9 0.0 3.2e-29 101.3 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EME32710.1 - 1.2e-23 82.6 0.0 1.4e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EME32710.1 - 3.4e-15 55.9 0.1 5.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EME32710.1 - 6.4e-13 48.7 0.0 1.7e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EME32710.1 - 1.9e-11 43.7 0.0 5.3e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_6 PF00562.23 EME32711.1 - 1.3e-112 376.3 0.0 1.9e-112 375.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME32711.1 - 5.2e-30 103.9 0.0 3.3e-29 101.2 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EME32711.1 - 1.2e-23 82.6 0.0 1.4e-22 79.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EME32711.1 - 3.4e-15 55.9 0.1 5.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EME32711.1 - 6.6e-13 48.7 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EME32711.1 - 2e-11 43.6 0.0 5.4e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain NUDIX_2 PF13869.1 EME32712.1 - 9.7e-70 233.7 0.0 1.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 EME32712.1 - 4.6e-07 29.5 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain P2 PF07194.6 EME32712.1 - 0.051 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain Peptidase_M3 PF01432.15 EME32713.1 - 1.1e-103 347.7 2.6 1.6e-103 347.2 1.8 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EME32713.1 - 0.022 14.1 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like DUF1319 PF07028.6 EME32713.1 - 0.024 14.8 1.3 5.7 7.1 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1319) NUC153 PF08159.7 EME32714.1 - 3.5e-10 39.2 3.0 4.3e-10 39.0 0.3 2.5 2 0 0 2 2 2 1 NUC153 domain DUF1657 PF07870.6 EME32714.1 - 0.0069 16.0 0.1 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1657) MS_channel PF00924.13 EME32715.1 - 7.1e-31 107.1 0.5 1.1e-30 106.4 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Ribosomal_S16 PF00886.14 EME32716.1 - 7.7e-22 76.7 0.0 1.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L24e PF01246.15 EME32717.1 - 6.5e-30 102.7 2.5 6.5e-30 102.7 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4238 PF14022.1 EME32717.1 - 0.011 15.0 0.3 0.015 14.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) zf-FCS PF06467.9 EME32717.1 - 0.19 11.4 2.3 0.38 10.4 1.6 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Aldedh PF00171.17 EME32718.1 - 1.6e-140 468.4 0.1 1.9e-140 468.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME32718.1 - 0.0015 17.3 0.0 0.004 15.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-C2H2_2 PF12756.2 EME32719.1 - 4.8e-31 106.8 13.8 2e-25 88.8 1.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EME32719.1 - 1.1e-15 57.2 21.4 1.8e-07 31.1 4.2 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME32719.1 - 1e-10 41.4 21.7 0.00015 21.8 4.1 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EME32719.1 - 0.0016 18.6 17.9 0.18 12.2 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME32719.1 - 0.035 14.4 19.2 0.097 13.0 0.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.7 EME32719.1 - 0.042 13.6 17.9 0.4 10.4 0.2 3.8 3 1 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 EME32719.1 - 0.5 10.3 19.0 0.38 10.7 2.9 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_2 PF12674.2 EME32719.1 - 0.87 9.9 4.3 0.79 10.1 0.4 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain FYVE PF01363.16 EME32719.1 - 1 9.3 11.0 1.6 8.6 0.8 3.1 3 0 0 3 3 3 0 FYVE zinc finger zf-DBF PF07535.7 EME32719.1 - 1.2 8.8 17.3 0.19 11.4 1.1 3.1 3 0 0 3 3 3 0 DBF zinc finger Yippee-Mis18 PF03226.9 EME32719.1 - 3.7 7.6 7.1 0.49 10.4 0.5 2.6 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LIM PF00412.17 EME32719.1 - 5.6 7.1 10.8 7.3 6.7 0.4 3.1 3 0 0 3 3 3 0 LIM domain C1_4 PF07975.7 EME32719.1 - 6.2 6.9 8.3 2.1 8.4 0.3 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain UDPGP PF01704.13 EME32720.1 - 1.5e-182 606.8 0.1 1.8e-182 606.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF972 PF06156.8 EME32721.1 - 0.042 14.2 2.1 0.047 14.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EME32721.1 - 0.058 13.3 1.4 0.067 13.1 1.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Med28 PF11594.3 EME32721.1 - 0.062 13.5 0.5 0.071 13.3 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 Atg14 PF10186.4 EME32721.1 - 0.093 11.6 2.3 0.093 11.6 1.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBCA PF02970.11 EME32721.1 - 0.11 12.5 1.8 0.17 11.9 1.2 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor A Opi1 PF08618.5 EME32721.1 - 0.11 11.3 0.2 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 DUF4248 PF14053.1 EME32721.1 - 0.14 11.7 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Vac_Fusion PF02346.11 EME32721.1 - 0.17 11.3 1.5 0.28 10.6 1.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein bZIP_1 PF00170.16 EME32721.1 - 0.59 10.1 5.4 0.87 9.5 3.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor ABC1 PF03109.11 EME32722.1 - 9e-36 122.4 0.0 1.6e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MBOAT PF03062.14 EME32723.1 - 1.1e-21 77.3 22.2 1.1e-21 77.3 15.4 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family KRTAP PF11759.3 EME32725.1 - 3 8.1 21.1 9 6.6 14.7 1.7 1 1 0 1 1 1 0 Keratin-associated matrix DMAP1 PF05499.7 EME32726.1 - 1.7e-15 57.0 0.2 3.2e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.26 EME32726.1 - 0.00032 20.6 0.1 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32726.1 - 0.0021 18.1 0.9 0.0087 16.1 0.6 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain GHL5 PF14872.1 EME32726.1 - 0.04 11.6 0.1 0.058 11.1 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Senescence_reg PF04520.8 EME32727.1 - 0.048 14.1 2.3 0.11 13.0 1.1 2.0 1 1 0 1 1 1 0 Senescence regulator Ribosomal_L37 PF08561.5 EME32729.1 - 4.3e-13 48.6 0.7 6.4e-13 48.0 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 SQS_PSY PF00494.14 EME32730.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase EamA PF00892.15 EME32730.1 - 0.17 11.9 1.7 0.41 10.7 1.2 1.7 1 1 0 1 1 1 0 EamA-like transporter family Potass_KdpF PF09604.5 EME32730.1 - 5.1 7.0 6.5 1.7 8.5 0.3 2.3 2 0 0 2 2 2 0 F subunit of K+-transporting ATPase (Potass_KdpF) Arch_ATPase PF01637.13 EME32731.1 - 0.026 14.1 0.1 0.21 11.2 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase SAM_1 PF00536.25 EME32732.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arch_ATPase PF01637.13 EME32733.1 - 0.021 14.5 0.3 0.18 11.4 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase DUF1192 PF06698.6 EME32735.1 - 0.0026 17.5 2.8 0.0026 17.5 1.9 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1192) AMP-binding PF00501.23 EME32736.1 - 2.3e-83 279.9 0.0 2.8e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32736.1 - 2.2e-21 76.5 0.8 4.5e-21 75.5 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.12 EME32738.1 - 3.1e-65 218.9 0.0 4.2e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Rubis-subs-bind PF09273.6 EME32739.1 - 7.1e-17 61.5 0.5 1.2e-16 60.8 0.4 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EME32739.1 - 0.011 16.0 0.1 0.032 14.5 0.1 1.9 1 1 0 1 1 1 0 SET domain SET PF00856.23 EME32740.1 - 0.0048 17.2 0.1 0.016 15.5 0.1 1.9 1 1 0 1 1 1 1 SET domain Glycolytic PF00274.14 EME32741.1 - 4.1e-174 577.9 0.0 4.6e-174 577.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ATP12 PF07542.6 EME32742.1 - 1.3e-29 102.6 0.0 2.2e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF1517 PF07466.6 EME32743.1 - 7.3e-75 251.6 0.0 8.8e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Cellulose_synt PF03552.9 EME32743.1 - 0.00053 18.4 0.0 0.00082 17.8 0.0 1.2 1 0 0 1 1 1 1 Cellulose synthase RRM_1 PF00076.17 EME32744.1 - 2.7e-55 183.8 0.0 5.2e-18 64.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME32744.1 - 3.8e-42 142.1 0.0 5.2e-14 51.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME32744.1 - 3e-18 65.4 0.0 0.00024 20.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME32744.1 - 3e-05 23.6 0.0 0.29 10.8 0.0 3.3 3 1 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.1 EME32744.1 - 0.1 12.3 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Oxysterol_BP PF01237.13 EME32745.1 - 5.2e-76 255.4 0.5 8.8e-76 254.6 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein YjcZ PF13990.1 EME32746.1 - 9.8 5.2 30.4 0.091 11.8 2.9 3.8 1 1 3 4 4 4 0 YjcZ-like protein E1-E2_ATPase PF00122.15 EME32747.1 - 1.5e-15 56.8 0.2 1.5e-15 56.8 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EME32747.1 - 2.4e-13 50.9 0.0 4.3e-10 40.3 0.0 3.5 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME32747.1 - 1.9e-10 41.2 0.1 2.7e-09 37.4 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME32747.1 - 1.3e-08 34.6 0.0 3e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD_2 PF13419.1 EME32747.1 - 0.047 13.9 0.1 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME32747.1 - 0.049 13.1 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Helicase_C PF00271.26 EME32748.1 - 5e-11 42.3 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EME32748.1 - 6e-07 28.7 0.1 1.6e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal AAA_14 PF13173.1 EME32748.1 - 0.031 14.1 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ThiS PF02597.15 EME32748.1 - 0.17 12.3 0.0 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 ThiS family MIS13 PF08202.6 EME32749.1 - 0.0056 15.7 0.8 0.0067 15.5 0.5 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Spc7 PF08317.6 EME32749.1 - 0.0065 15.1 0.4 0.0079 14.8 0.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein COG5 PF10392.4 EME32749.1 - 0.046 13.6 0.7 0.067 13.1 0.5 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 IMD PF08397.6 EME32749.1 - 0.074 12.3 0.4 0.093 12.0 0.3 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Snapin_Pallidin PF14712.1 EME32749.1 - 0.15 12.4 1.1 0.35 11.1 0.8 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Vanabin-2 PF11437.3 EME32750.1 - 0.3 11.0 31.8 9.1 6.3 12.9 2.6 1 1 1 2 2 2 0 Vanadium-binding protein 2 RCC1 PF00415.13 EME32751.1 - 2.7e-63 209.9 23.0 1.7e-11 44.1 0.0 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME32751.1 - 5.1e-36 121.5 25.6 1.3e-07 30.9 0.0 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EME32751.1 - 1.6e-12 47.3 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RCC1 PF00415.13 EME32752.1 - 1.3e-62 207.7 23.0 2.1e-11 43.8 0.0 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME32752.1 - 3.3e-36 122.1 23.0 1.6e-07 30.7 0.0 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EME32752.1 - 9.8e-22 77.0 0.0 8.4e-21 74.0 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Aminotran_5 PF00266.14 EME32753.1 - 2.6e-40 138.3 0.0 3.3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME32753.1 - 0.00055 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME32753.1 - 0.0011 17.3 0.0 0.0018 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AAA_25 PF13481.1 EME32753.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.13 EME32754.1 - 7.9e-42 143.1 34.3 9.1e-42 142.9 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.3 EME32754.1 - 0.39 10.7 0.1 0.39 10.7 0.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) ABC1 PF03109.11 EME32755.1 - 5e-25 87.7 0.1 8.8e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EME32755.1 - 1.9e-05 24.5 1.4 0.00026 20.7 1.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EME32755.1 - 0.01 14.9 0.1 0.043 12.9 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Thioredoxin PF00085.15 EME32756.1 - 1.6e-19 69.5 0.0 4.5e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME32756.1 - 7.3e-05 22.9 0.1 0.001 19.2 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME32756.1 - 0.00074 19.5 0.0 0.003 17.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EME32756.1 - 0.0013 18.4 0.1 0.016 14.9 0.0 2.2 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EME32756.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like ERp29_N PF07912.8 EME32756.1 - 0.042 13.7 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 ERp29, N-terminal domain HyaE PF07449.6 EME32756.1 - 0.056 13.3 0.1 0.27 11.1 0.0 2.2 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 EME32756.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Redoxin Ribosomal_L13e PF01294.13 EME32756.1 - 0.094 12.1 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L13e zf-RING_2 PF13639.1 EME32757.1 - 2.5e-14 52.7 6.9 2.5e-14 52.7 4.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME32757.1 - 9.8e-08 31.9 6.9 9.8e-08 31.9 4.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME32757.1 - 4.8e-06 26.1 5.0 4.8e-06 26.1 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME32757.1 - 7.4e-06 25.5 6.7 7.4e-06 25.5 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME32757.1 - 1.9e-05 24.3 4.7 1.9e-05 24.3 3.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME32757.1 - 3e-05 24.0 11.3 3e-05 24.0 7.8 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME32757.1 - 0.12 12.1 5.8 0.42 10.4 4.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EME32757.1 - 0.18 11.6 8.6 0.25 11.1 1.7 3.1 3 1 0 3 3 3 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EME32757.1 - 0.33 10.7 6.0 1.3 8.8 4.2 2.2 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EME32757.1 - 9.8 6.2 12.0 18 5.4 4.9 3.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 EME32758.1 - 3.2e-10 39.6 10.0 6e-10 38.7 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME32758.1 - 1.6e-06 28.1 10.0 5.4e-06 26.4 6.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME32758.1 - 4.8e-06 26.1 8.9 9.2e-06 25.2 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME32758.1 - 0.00017 21.5 9.6 0.00034 20.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME32758.1 - 0.0009 18.8 9.5 0.0016 18.0 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME32758.1 - 0.0058 16.4 4.2 0.014 15.2 2.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME32758.1 - 0.052 13.2 11.6 0.089 12.5 8.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Adeno_E3_CR2 PF02439.10 EME32758.1 - 0.64 9.6 5.4 0.26 10.8 1.9 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRR19-TM PF15176.1 EME32758.1 - 2.8 7.6 5.3 6.1 6.5 1.4 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain SAICAR_synt PF01259.13 EME32759.1 - 5.7e-78 261.4 0.0 7.8e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.15 EME32759.1 - 3.3e-37 127.0 0.0 4.5e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 AIR carboxylase DUF241 PF03087.9 EME32759.1 - 0.091 12.2 0.3 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function zf-DHHC PF01529.15 EME32760.1 - 1.3e-41 141.9 6.5 1.3e-41 141.9 4.5 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Tissue_fac PF01108.12 EME32760.1 - 0.035 13.8 0.9 0.074 12.7 0.6 1.6 1 0 0 1 1 1 0 Tissue factor DZR PF12773.2 EME32760.1 - 1.9 8.3 8.2 3.7 7.4 5.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon RimM PF01782.13 EME32761.1 - 1.9e-14 53.3 0.0 7.2e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 RimM N-terminal domain Solute_trans_a PF03619.11 EME32762.1 - 1.4e-85 286.9 5.9 1.6e-85 286.7 4.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-RING_2 PF13639.1 EME32763.1 - 3.5e-13 49.1 6.0 3.5e-13 49.1 4.2 3.8 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EME32763.1 - 9.4e-10 38.4 18.3 1.6e-08 34.5 5.8 3.6 1 1 2 3 3 3 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME32763.1 - 2.4e-08 33.5 4.6 2.4e-08 33.5 3.2 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME32763.1 - 4e-07 29.9 6.2 4e-07 29.9 4.3 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME32763.1 - 2.1e-06 27.3 3.8 2.1e-06 27.3 2.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME32763.1 - 6.3e-06 25.8 11.2 6.3e-05 22.6 2.9 2.8 2 0 0 2 2 2 2 zinc-RING finger domain RINGv PF12906.2 EME32763.1 - 0.00033 20.6 11.1 0.0021 18.0 4.1 3.1 2 0 0 2 2 2 1 RING-variant domain zf-Apc11 PF12861.2 EME32763.1 - 0.0042 16.8 14.0 0.21 11.4 7.4 3.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3134 PF11332.3 EME32763.1 - 0.0047 17.0 0.1 0.025 14.6 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3134) zf-C3HC4_4 PF15227.1 EME32763.1 - 0.016 15.0 4.1 0.15 11.9 2.8 2.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2695 PF10905.3 EME32763.1 - 0.026 14.2 0.3 0.09 12.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) DNA_ligase_ZBD PF03119.11 EME32763.1 - 0.054 13.2 0.4 1.4 8.6 0.0 3.0 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_4 PF14570.1 EME32763.1 - 0.26 10.8 6.7 0.046 13.3 1.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EME32763.1 - 0.29 10.9 3.5 0.31 10.8 1.0 2.1 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 EME32763.1 - 0.46 10.4 13.2 0.27 11.2 2.4 3.6 3 1 1 4 4 4 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EME32763.1 - 1.8 8.3 6.5 2 8.2 3.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EME32763.1 - 6.8 6.3 12.0 0.1 12.1 1.5 2.6 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit UPF0547 PF10571.4 EME32763.1 - 9.9 5.9 10.2 0.64 9.7 0.2 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Abhydro_lipase PF04083.11 EME32764.1 - 4.9e-20 70.6 0.0 9e-20 69.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EME32764.1 - 2.8e-08 33.9 0.1 4.6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME32764.1 - 6.1e-08 32.4 0.0 9.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME32764.1 - 1.6e-06 27.8 0.0 6.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME32764.1 - 0.017 14.5 0.0 0.059 12.7 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2294 PF10057.4 EME32765.1 - 0.083 12.5 0.4 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) NUDIX PF00293.23 EME32766.1 - 5e-13 48.8 0.2 6.8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NYN PF01936.13 EME32767.1 - 2.4e-20 73.3 0.0 4.8e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 NYN domain CBM_25 PF03423.8 EME32767.1 - 8.9e-12 44.9 1.0 1.7e-11 44.0 0.7 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) NYN PF01936.13 EME32768.1 - 1.9e-20 73.6 0.0 3.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 NYN domain CBM_25 PF03423.8 EME32768.1 - 6.6e-12 45.3 1.0 1.2e-11 44.5 0.7 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Methyltransf_28 PF02636.12 EME32769.1 - 2e-29 102.7 0.0 3.9e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EME32769.1 - 0.005 17.3 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME32769.1 - 0.042 14.4 0.1 0.2 12.2 0.0 2.2 2 1 1 3 3 3 0 Methyltransferase domain DUF342 PF03961.8 EME32769.1 - 0.27 9.6 2.8 0.5 8.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_C1_2 PF03051.10 EME32770.1 - 4.6e-184 612.0 0.3 5.2e-184 611.8 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EME32770.1 - 2.6e-05 24.2 0.3 0.00038 20.4 0.2 2.3 2 0 0 2 2 2 1 Papain family cysteine protease Ribosomal_L18e PF00828.14 EME32771.1 - 1.9e-36 125.2 0.1 2.5e-36 124.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Myb_DNA-binding PF00249.26 EME32772.1 - 1.9e-53 178.2 23.3 1.2e-13 50.8 0.1 6.4 6 0 0 6 6 6 6 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME32772.1 - 5.5e-52 173.7 31.3 6.1e-15 55.0 0.1 6.8 4 1 3 7 7 7 6 Myb-like DNA-binding domain HTH_23 PF13384.1 EME32772.1 - 2e-05 24.0 0.5 0.73 9.5 0.0 4.4 4 0 0 4 4 4 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EME32772.1 - 7.3e-05 22.1 0.4 0.051 13.0 0.0 3.7 4 0 0 4 4 4 1 Sigma-70, region 4 SLIDE PF09111.5 EME32772.1 - 8.1e-05 22.3 0.6 0.76 9.5 0.0 3.6 2 1 1 3 3 3 1 SLIDE HTH_38 PF13936.1 EME32772.1 - 0.00024 20.5 0.3 0.072 12.6 0.0 3.5 4 0 0 4 4 4 1 Helix-turn-helix domain DUF3102 PF11300.3 EME32772.1 - 0.0031 17.5 1.1 4.3 7.3 0.0 3.6 2 2 1 4 4 4 1 Protein of unknown function (DUF3102) HTH_24 PF13412.1 EME32772.1 - 0.0081 15.5 0.8 9.1 5.7 0.2 3.7 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding GcrA PF07750.6 EME32772.1 - 0.011 16.0 3.0 0.32 11.1 0.0 3.0 3 0 0 3 3 3 0 GcrA cell cycle regulator HTH_AsnC-type PF13404.1 EME32772.1 - 0.026 14.0 0.6 1.2 8.7 0.1 3.5 4 1 0 4 4 4 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 EME32772.1 - 0.033 13.4 0.1 0.65 9.3 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 TryThrA_C PF12319.3 EME32772.1 - 0.18 10.9 16.1 0.14 11.3 1.6 3.6 3 1 2 5 5 5 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Spuma_A9PTase PF03539.9 EME32772.1 - 0.2 11.5 3.7 23 4.8 0.1 3.4 1 1 2 3 3 3 0 Spumavirus aspartic protease (A9) WIYLD PF10440.4 EME32772.1 - 0.28 11.1 6.1 14 5.6 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-binding WIYLD domain DUF3641 PF12345.3 EME32773.1 - 1.2e-46 157.8 2.9 1.8e-46 157.3 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.16 EME32773.1 - 3.3e-05 24.1 0.0 5.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EME32773.1 - 0.0026 17.7 0.0 0.0086 16.0 0.0 1.9 1 1 1 2 2 2 1 4Fe-4S single cluster domain WD40 PF00400.27 EME32774.1 - 3.4e-17 61.5 3.0 0.0013 18.5 0.1 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Lactamase_B_2 PF12706.2 EME32775.1 - 5.4e-21 75.0 0.1 7e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME32775.1 - 2.8e-11 43.4 0.4 6.6e-11 42.2 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EME32775.1 - 0.00086 19.0 0.1 0.0037 16.9 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UPF0016 PF01169.14 EME32776.1 - 3.1e-43 145.7 17.7 3.5e-23 81.5 1.9 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 YrhK PF14145.1 EME32776.1 - 0.027 14.1 1.5 0.061 12.9 0.4 2.1 2 0 0 2 2 2 0 YrhK-like protein DUF2967 PF11179.3 EME32776.1 - 0.032 13.7 0.8 0.052 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Phage_holin_3 PF05106.7 EME32776.1 - 0.06 13.3 0.3 0.06 13.3 0.2 2.2 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DUF204 PF02659.10 EME32776.1 - 1.3 9.1 10.9 6.2 7.0 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF DUF3984 PF13136.1 EME32776.1 - 1.3 8.1 8.3 2 7.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) FTR1 PF03239.9 EME32776.1 - 4.8 6.0 10.0 1.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Iron permease FTR1 family Mucin PF01456.12 EME32776.1 - 6.8 6.4 5.6 0.64 9.7 0.1 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein zf-LITAF-like PF10601.4 EME32776.1 - 8.9 6.2 9.8 0.41 10.5 1.0 2.8 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain IMS PF00817.15 EME32777.1 - 2e-40 138.0 0.2 3.9e-40 137.0 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 EME32777.1 - 1.1e-06 28.6 0.0 3.2e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EME32777.1 - 8.9e-05 22.3 0.1 0.0022 17.9 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EME32777.1 - 0.00018 21.2 0.1 0.00071 19.3 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain DNA_processg_A PF02481.10 EME32778.1 - 0.00053 18.9 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A HEAT_2 PF13646.1 EME32779.1 - 5.9e-43 145.0 11.1 2e-10 40.8 0.0 6.0 4 2 2 6 6 6 6 HEAT repeats HEAT PF02985.17 EME32779.1 - 2.7e-17 61.2 8.2 0.14 12.3 0.0 10.4 9 3 2 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 EME32779.1 - 2.8e-11 43.5 6.6 0.00076 19.8 0.0 7.9 5 4 4 9 9 9 2 HEAT-like repeat HEAT_PBS PF03130.11 EME32779.1 - 6.4e-08 32.3 1.3 1.6 9.3 0.4 7.3 8 0 0 8 8 8 1 PBS lyase HEAT-like repeat Arm PF00514.18 EME32779.1 - 0.00043 20.0 0.2 5.4 6.9 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EME32779.1 - 0.043 13.7 2.2 9.8 6.1 0.0 4.8 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 UPF0147 PF03685.8 EME32779.1 - 0.11 12.4 2.3 5.5 6.9 0.0 4.1 3 2 1 4 4 4 0 Uncharacterised protein family (UPF0147) HEAT_2 PF13646.1 EME32780.1 - 5.9e-43 145.0 11.1 2e-10 40.8 0.0 6.0 4 2 2 6 6 6 6 HEAT repeats HEAT PF02985.17 EME32780.1 - 2.7e-17 61.2 8.2 0.14 12.3 0.0 10.4 9 3 2 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 EME32780.1 - 2.8e-11 43.5 6.6 0.00076 19.8 0.0 7.9 5 4 4 9 9 9 2 HEAT-like repeat HEAT_PBS PF03130.11 EME32780.1 - 6.4e-08 32.3 1.3 1.6 9.3 0.4 7.3 8 0 0 8 8 8 1 PBS lyase HEAT-like repeat Arm PF00514.18 EME32780.1 - 0.00043 20.0 0.2 5.4 6.9 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EME32780.1 - 0.043 13.7 2.2 9.8 6.1 0.0 4.8 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 UPF0147 PF03685.8 EME32780.1 - 0.11 12.4 2.3 5.5 6.9 0.0 4.1 3 2 1 4 4 4 0 Uncharacterised protein family (UPF0147) Methyltransf_16 PF10294.4 EME32781.1 - 6.9e-16 58.1 0.0 7.7e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME32781.1 - 0.0066 15.8 0.0 0.0094 15.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME32781.1 - 0.026 13.6 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EME32781.1 - 0.068 12.2 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.10 EME32781.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.4 EME32782.1 - 1.1e-18 67.2 0.0 1.4e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME32782.1 - 0.0054 16.1 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME32782.1 - 0.036 13.1 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EME32782.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.10 EME32782.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ras PF00071.17 EME32783.1 - 4.3e-49 166.0 0.1 5.9e-49 165.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME32783.1 - 1.6e-13 51.1 0.0 3.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME32783.1 - 2.6e-09 36.5 0.1 3.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME32783.1 - 7.7e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME32783.1 - 0.057 12.5 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mito_carr PF00153.22 EME32784.1 - 6.9e-58 192.3 1.6 1.2e-23 82.5 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein CDP-OH_P_transf PF01066.16 EME32785.1 - 2.6e-16 59.7 3.4 3.2e-16 59.4 2.4 1.1 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Duffy_binding PF05424.6 EME32786.1 - 0.037 13.8 0.1 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Duffy binding domain DUF3783 PF12646.2 EME32786.1 - 0.085 12.6 0.3 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) PPR_2 PF13041.1 EME32788.1 - 1.7e-118 386.5 14.7 3.9e-17 61.9 0.1 12.4 1 1 13 14 14 14 14 PPR repeat family PPR_1 PF12854.2 EME32788.1 - 6.2e-76 249.5 10.6 2.7e-11 42.7 0.0 13.9 13 2 0 13 13 13 12 PPR repeat PPR_3 PF13812.1 EME32788.1 - 1.4e-70 227.7 0.3 3.4e-08 33.1 0.0 13.9 14 1 0 14 14 14 11 Pentatricopeptide repeat domain PPR PF01535.15 EME32788.1 - 2.2e-70 227.9 22.7 1.7e-09 37.0 0.0 15.1 14 1 0 14 14 14 11 PPR repeat ECSIT PF06239.6 EME32788.1 - 3.9e-11 42.2 0.0 1.8 7.3 0.0 7.6 2 1 5 7 7 7 4 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.2 EME32788.1 - 1.1e-05 24.7 0.0 9 5.6 0.0 5.1 3 2 0 5 5 5 2 Mitochondrial ATPase expression MRP-S27 PF10037.4 EME32788.1 - 9.4e-05 21.4 0.9 4 6.2 0.0 4.3 4 1 1 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.1 EME32788.1 - 0.00011 22.5 0.0 1.3e+02 3.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME32788.1 - 0.00055 19.5 0.0 2.9 7.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Rep_fac_C PF08542.6 EME32788.1 - 0.018 14.9 0.0 23 5.0 0.0 3.6 2 1 0 3 3 3 0 Replication factor C C-terminal domain CpeT PF06206.6 EME32789.1 - 1.3e-54 184.5 0.4 1.9e-54 184.0 0.0 1.4 2 0 0 2 2 2 1 CpeT/CpcT family (DUF1001) EAP30 PF04157.11 EME32790.1 - 2.9e-51 173.7 0.4 2.9e-51 173.7 0.3 1.6 2 0 0 2 2 2 1 EAP30/Vps36 family HTH_24 PF13412.1 EME32790.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DIL PF01843.14 EME32790.1 - 0.013 15.3 0.7 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 DIL domain Fib_alpha PF08702.5 EME32790.1 - 0.041 14.0 1.6 0.25 11.4 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.4 EME32790.1 - 1.8 8.8 5.2 0.94 9.7 1.2 2.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) LRS4 PF10422.4 EME32790.1 - 5.3 6.3 9.0 11 5.2 6.2 1.7 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DHquinase_I PF01487.10 EME32791.1 - 1.9e-53 181.3 0.0 2.7e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EME32791.1 - 5.4e-24 84.0 0.0 3e-23 81.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EME32791.1 - 4.3e-14 52.7 0.0 9.7e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EME32791.1 - 0.00022 21.6 0.0 0.00099 19.4 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME32791.1 - 0.0061 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EME32791.1 - 0.03 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase PRK PF00485.13 EME32792.1 - 0.0048 16.4 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EME32792.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UDP-g_GGTase PF06427.6 EME32793.1 - 5.6e-41 140.1 0.3 1.1e-40 139.1 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EME32793.1 - 2.9e-08 33.3 0.1 1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 8 zf-Tim10_DDP PF02953.10 EME32795.1 - 2.3e-18 65.2 4.6 2.3e-18 65.2 3.2 1.6 2 0 0 2 2 2 1 Tim10/DDP family zinc finger NatB_MDM20 PF09797.4 EME32795.1 - 0.012 14.3 1.6 0.012 14.2 1.1 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit FTR PF01913.13 EME32795.1 - 0.12 12.1 0.1 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Pro_isomerase PF00160.16 EME32796.1 - 2.3e-44 151.3 0.0 2.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_jaz PF12171.3 EME32797.1 - 0.082 13.0 0.3 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DnaJ PF00226.26 EME32798.1 - 1.4e-16 59.9 2.5 5.4e-16 58.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2764 PF10962.3 EME32799.1 - 0.011 15.0 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Mrr_cat_2 PF13156.1 EME32799.1 - 0.015 15.2 0.1 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease M60-like PF13402.1 EME32799.1 - 0.046 12.6 0.0 0.05 12.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase M60-like family UCH PF00443.24 EME32801.1 - 1.2e-26 93.4 2.8 1.5e-26 93.1 2.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME32801.1 - 2.1e-16 60.2 2.3 9e-16 58.1 1.6 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ROK PF00480.15 EME32802.1 - 3.9e-28 98.4 0.0 4.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.11 EME32802.1 - 0.0038 16.0 0.2 0.0075 15.0 0.1 1.4 2 0 0 2 2 2 1 Glucokinase DUF3287 PF11690.3 EME32803.1 - 0.033 14.2 0.1 0.033 14.2 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.6 EME32803.1 - 3.9 7.4 8.3 3.2 7.7 0.2 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) PDH PF02153.12 EME32804.1 - 7.4e-13 47.9 0.0 1.3e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EME32804.1 - 7.9e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME32804.1 - 6.7e-07 28.6 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME32804.1 - 1.8e-05 24.6 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EME32804.1 - 0.0013 18.1 0.0 0.0039 16.6 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 EME32804.1 - 0.0072 16.8 0.1 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 EME32804.1 - 0.0077 15.9 0.1 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EME32804.1 - 0.0099 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EME32804.1 - 0.053 13.1 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EME32804.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EME32804.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 EME32804.1 - 0.13 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Rossmann-like PF10727.4 EME32804.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EME32804.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EME32804.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase BLOC1_2 PF10046.4 EME32804.1 - 0.15 12.2 0.3 0.56 10.3 0.1 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SpoU_methylase PF00588.14 EME32805.1 - 1.7e-28 99.2 0.0 2.6e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EME32805.1 - 4.6e-05 23.4 0.0 0.00022 21.3 0.0 2.2 1 1 1 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding LIM PF00412.17 EME32807.1 - 1.4e-22 79.4 14.2 2.4e-12 46.7 3.1 3.2 2 1 1 3 3 3 2 LIM domain MULE PF10551.4 EME32807.1 - 0.027 14.6 0.8 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 MULE transposase domain DNase-RNase PF02577.9 EME32808.1 - 4.8e-24 84.1 0.0 9.8e-24 83.1 0.0 1.4 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.14 EME32808.1 - 9.2e-07 28.1 0.7 2.8e-06 26.6 0.5 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif 3H PF02829.9 EME32808.1 - 0.053 13.5 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 3H domain AAA_23 PF13476.1 EME32808.1 - 0.13 12.5 0.6 0.18 12.1 0.4 1.2 1 0 0 1 1 1 0 AAA domain FYRC PF05965.9 EME32809.1 - 3.6e-08 33.1 0.0 1.5e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.9 EME32809.1 - 6.1e-06 25.5 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus Myb_DNA-binding PF00249.26 EME32809.1 - 8.5e-05 22.5 1.5 0.29 11.2 0.0 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain FHA PF00498.21 EME32809.1 - 9.2e-05 22.4 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain CHDCT2 PF08074.6 EME32809.1 - 0.00017 21.3 0.2 0.44 10.2 0.0 3.3 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain Myc_N PF01056.13 EME32809.1 - 0.036 13.2 8.2 0.062 12.4 5.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EME32809.1 - 0.5 8.7 13.8 0.78 8.1 9.5 1.2 1 0 0 1 1 1 0 Daxx Family 2-Hacid_dh_C PF02826.14 EME32810.1 - 2.8e-55 186.2 0.0 4.9e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME32810.1 - 1.6e-35 121.4 0.0 2.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME32810.1 - 3.6e-05 23.6 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EME32810.1 - 0.00022 20.5 0.0 0.00061 19.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EME32810.1 - 0.043 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EME32810.1 - 0.073 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Slu7 PF11708.3 EME32812.1 - 5.3e-67 226.0 11.3 5.3e-67 226.0 7.8 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF726 PF05277.7 EME32813.1 - 6.3e-76 255.4 5.8 5.7e-61 206.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EME32813.1 - 0.0032 17.3 0.1 0.0092 15.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME32813.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME32813.1 - 0.014 15.1 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EME32813.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 EME32813.1 - 0.063 13.4 0.1 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Radical_SAM PF04055.16 EME32814.1 - 3.1e-35 121.7 0.1 2e-34 119.1 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 EME32814.1 - 4e-29 100.3 0.2 1.2e-28 98.8 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 DUF4187 PF13821.1 EME32814.1 - 0.075 12.6 0.0 0.34 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) Ank_2 PF12796.2 EME32815.1 - 4.9e-13 49.2 0.1 9.3e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME32815.1 - 1.8e-09 36.9 0.1 2e-08 33.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EME32815.1 - 1.9e-09 37.7 0.1 2.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME32815.1 - 9.8e-09 34.6 0.0 2.8e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EME32815.1 - 1e-08 35.1 0.0 3.3e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF393 PF04134.7 EME32816.1 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Actin PF00022.14 EME32817.1 - 2.3e-151 503.6 0.0 2.6e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 Actin Metallophos PF00149.23 EME32818.1 - 1.5e-13 50.5 0.4 4.3e-13 49.1 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME32818.1 - 1.2e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_CG PF14542.1 EME32819.1 - 2.2e-25 88.3 0.0 2.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 EME32819.1 - 0.053 13.5 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AMP-binding PF00501.23 EME32820.1 - 3.9e-94 315.3 0.0 5.3e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32820.1 - 0.076 13.9 0.0 0.18 12.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Exo_endo_phos PF03372.18 EME32821.1 - 1.8e-13 51.0 0.0 3.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME32821.1 - 0.052 13.1 0.0 0.18 11.4 0.0 2.0 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase NKWYS PF10364.4 EME32821.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Prion_bPrPp PF11587.3 EME32821.1 - 0.81 9.4 3.7 0.35 10.5 0.2 2.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal FixQ PF05545.6 EME32821.1 - 1.4 8.6 3.9 9.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ ABC_tran PF00005.22 EME32822.1 - 8.2e-27 94.1 0.0 1.4e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EME32822.1 - 1.9e-18 66.6 20.0 3.3e-18 65.8 13.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EME32822.1 - 5.6e-11 42.9 0.1 7e-09 36.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EME32822.1 - 0.0095 15.0 0.0 0.14 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EME32822.1 - 0.017 14.5 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EME32822.1 - 0.024 14.2 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EME32822.1 - 0.037 12.6 0.6 2.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EME32822.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EME32822.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 EME32822.1 - 0.085 12.2 0.1 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 EME32822.1 - 0.094 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME32822.1 - 0.11 12.8 0.2 0.32 11.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EME32822.1 - 0.16 11.4 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DnaJ PF00226.26 EME32823.1 - 3.8e-26 90.6 2.2 2.3e-25 88.1 0.1 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EME32823.1 - 1.6e-09 37.6 8.9 3.3e-08 33.4 2.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME32823.1 - 2.7e-08 33.7 8.4 1.8e-06 27.9 1.9 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EME32823.1 - 1.1e-07 31.9 12.4 0.00062 19.8 0.7 3.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EME32823.1 - 3.5e-06 26.7 4.1 0.016 15.1 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME32823.1 - 1.7e-05 24.8 7.2 0.004 17.3 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME32823.1 - 3.7e-05 23.7 4.6 0.05 13.9 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME32823.1 - 0.016 15.5 2.7 3.2 8.1 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EME32823.1 - 0.048 13.4 3.2 0.96 9.2 0.7 2.6 2 0 0 2 2 2 0 BED zinc finger zf-FCS PF06467.9 EME32823.1 - 0.064 12.9 2.8 6.5 6.4 0.2 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Tmemb_55A PF09788.4 EME32823.1 - 0.081 12.0 0.1 0.63 9.1 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 55A zf-LYAR PF08790.6 EME32823.1 - 0.1 12.3 3.1 0.18 11.5 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met2 PF12907.2 EME32823.1 - 0.15 12.0 1.5 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding zinc_ribbon_5 PF13719.1 EME32823.1 - 0.42 10.2 3.0 4.6 6.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF2937 PF11157.3 EME32823.1 - 0.8 9.0 3.9 1.7 7.9 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Rtf2 PF04641.7 EME32824.1 - 1.3e-47 162.1 1.4 1.6e-47 161.8 1.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EME32824.1 - 9e-05 22.1 0.4 0.0018 17.9 0.0 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-Nse PF11789.3 EME32824.1 - 0.0028 17.1 2.3 0.049 13.1 0.0 2.8 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EME32824.1 - 0.0097 15.7 0.5 0.06 13.1 0.3 2.2 2 0 0 2 2 2 1 Ring finger domain Pkinase PF00069.20 EME32826.1 - 6e-66 222.2 0.0 8.5e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME32826.1 - 3.8e-44 150.7 0.0 5.4e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EME32826.1 - 1.1e-09 38.5 0.1 4.1e-09 36.7 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain APH PF01636.18 EME32826.1 - 0.0051 16.5 0.0 1.6 8.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME32826.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 EME32826.1 - 0.037 12.8 0.1 0.066 12.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Prefoldin PF02996.12 EME32827.1 - 6.3e-10 38.7 0.1 7.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EME32828.1 - 9.9e-10 38.1 0.1 1.1e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit HA2 PF04408.18 EME32829.1 - 2.2e-15 56.5 0.3 4.5e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME32829.1 - 4.6e-13 48.8 0.0 3.4e-12 46.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME32829.1 - 1.4e-05 24.6 0.2 3.6e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EME32829.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_23 PF13476.1 EME32829.1 - 0.0066 16.7 0.1 0.84 9.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EME32829.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME32829.1 - 0.024 14.6 0.1 0.22 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain PhoH PF02562.11 EME32829.1 - 0.048 12.8 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EME32829.1 - 0.1 12.4 0.2 6.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Trehalose_PPase PF02358.11 EME32830.1 - 4e-39 133.9 0.0 4.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.16 EME32831.1 - 4.3e-185 615.7 0.0 7.7e-183 608.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME32831.1 - 9.8e-07 27.9 0.0 1.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 EME32831.1 - 0.083 12.3 0.2 1.1 8.6 0.1 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EME32832.1 - 4.5e-185 615.6 0.0 7.9e-183 608.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME32832.1 - 6.3e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 EME32832.1 - 0.087 12.2 0.2 1.1 8.6 0.2 2.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 SLA_LP_auto_ag PF05889.8 EME32835.1 - 8.3e-127 422.8 0.1 1e-126 422.5 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 EME32835.1 - 0.029 13.1 0.5 0.042 12.5 0.3 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME32835.1 - 0.061 12.4 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EME32836.1 - 1.6e-120 402.1 0.1 8e-62 208.9 0.2 2.1 2 0 0 2 2 2 2 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 EME32836.1 - 0.12 11.5 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase HNH PF01844.18 EME32837.1 - 8e-13 48.0 0.9 1.5e-12 47.2 0.6 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.1 EME32837.1 - 9.8e-08 31.5 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.1 EME32837.1 - 0.0022 17.9 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF365 PF04033.7 EME32837.1 - 0.066 13.2 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) PyrI_C PF02748.10 EME32837.1 - 0.074 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.1 EME32837.1 - 0.18 12.2 1.1 0.66 10.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EME32837.1 - 0.44 10.9 2.3 0.8 10.1 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 EME32837.1 - 0.85 9.5 3.8 1.3 8.9 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain tRNA-synt_1 PF00133.17 EME32838.1 - 2e-37 128.4 0.0 1.3e-24 86.2 0.0 3.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EME32838.1 - 4.5e-22 78.2 0.1 2.5e-11 42.8 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EME32838.1 - 1.7e-12 47.1 0.1 3e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EME32838.1 - 1.5e-11 44.2 0.8 3.4e-11 43.1 0.5 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 EME32838.1 - 0.0042 15.8 0.0 0.0089 14.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (K) WD40 PF00400.27 EME32839.1 - 0.00049 19.8 3.1 0.067 13.1 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4520 PF15016.1 EME32839.1 - 0.0048 16.4 0.0 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) PQQ_2 PF13360.1 EME32839.1 - 0.022 14.2 0.0 0.076 12.4 0.0 1.8 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.27 EME32840.1 - 0.00064 19.4 3.1 0.071 13.0 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4520 PF15016.1 EME32840.1 - 0.0052 16.3 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) PQQ_2 PF13360.1 EME32840.1 - 0.046 13.1 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain FAT PF02259.18 EME32841.1 - 2.1e-30 105.8 10.6 2.4e-30 105.6 5.8 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EME32841.1 - 7.2e-11 41.9 0.2 2e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Selenoprotein_S PF06936.6 EME32841.1 - 0.11 12.0 2.0 0.28 10.7 1.4 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) bPH_2 PF03703.9 EME32842.1 - 1.7e-10 40.7 0.1 2.6e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial PH domain SAM_decarbox PF01536.11 EME32843.1 - 3.2e-85 285.7 1.4 5.1e-85 285.0 1.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Orn_Arg_deC_N PF02784.11 EME32843.1 - 6.5e-10 38.6 0.1 2.3e-09 36.7 0.0 1.9 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME32843.1 - 3.5e-06 26.7 0.0 6.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SAM_decarbox PF01536.11 EME32844.1 - 3.2e-85 285.7 1.4 5.1e-85 285.0 1.0 1.2 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Orn_Arg_deC_N PF02784.11 EME32844.1 - 6.5e-10 38.6 0.1 2.3e-09 36.7 0.0 1.9 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME32844.1 - 3.5e-06 26.7 0.0 6.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SAYSvFN PF10260.4 EME32845.1 - 0.046 13.4 4.8 3 7.6 0.4 2.7 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF1443 PF07280.6 EME32845.1 - 0.48 10.0 0.1 0.48 10.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1443) SAYSvFN PF10260.4 EME32846.1 - 0.046 13.4 4.8 3 7.6 0.4 2.7 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF1443 PF07280.6 EME32846.1 - 0.48 10.0 0.1 0.48 10.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1443) ERp29 PF07749.7 EME32847.1 - 0.048 14.2 4.0 2.1 9.0 0.6 3.5 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain AHS1 PF02682.11 EME32847.1 - 0.09 12.2 2.1 6.6 6.1 0.1 3.0 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 Mu-like_Pro PF10123.4 EME32847.1 - 0.11 11.8 0.5 2.4 7.5 0.2 2.4 2 0 0 2 2 2 0 Mu-like prophage I protein La PF05383.12 EME32848.1 - 4.6e-16 58.3 0.0 1.4e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 La domain GNT-I PF03071.10 EME32849.1 - 9.4e-42 143.0 2.8 1.8e-41 142.1 2.0 1.3 1 0 0 1 1 1 1 GNT-I family UPF0086 PF01868.11 EME32849.1 - 3e-12 46.0 0.0 7.9e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 GNT-I PF03071.10 EME32850.1 - 9e-42 143.1 2.8 1.7e-41 142.1 2.0 1.4 1 0 0 1 1 1 1 GNT-I family UPF0086 PF01868.11 EME32850.1 - 2.9e-12 46.0 0.0 7.7e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 UCH_1 PF13423.1 EME32851.1 - 5.1e-24 85.2 0.1 7e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EME32851.1 - 1.9e-20 73.7 0.0 4.4e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EME32851.1 - 1.4e-05 24.4 0.6 0.00012 21.2 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TP_methylase PF00590.15 EME32852.1 - 5.3e-22 78.5 0.0 6.9e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CENP-K PF11802.3 EME32853.1 - 0.11 11.7 2.8 0.17 11.0 1.9 1.3 1 0 0 1 1 1 0 Centromere-associated protein K CBF PF03914.12 EME32854.1 - 8.1e-30 103.4 2.9 2.1e-29 102.1 1.5 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Sec63 PF02889.11 EME32855.1 - 2.6e-28 99.1 0.0 6.8e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EME32855.1 - 1.2e-20 72.9 0.1 2.6e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.6 EME32855.1 - 0.44 9.7 7.3 0.4 9.8 0.1 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Rhomboid PF01694.17 EME32856.1 - 0.00098 19.1 10.4 0.00098 19.1 7.2 1.8 2 0 0 2 2 2 1 Rhomboid family MPC PF03650.8 EME32858.1 - 3.1e-38 130.3 1.3 3.4e-38 130.2 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Imm_superinfect PF14373.1 EME32858.1 - 0.19 11.4 1.7 21 4.8 0.1 3.0 3 0 0 3 3 3 0 Superinfection immunity protein AMP-binding PF00501.23 EME32859.1 - 1.3e-105 353.2 0.0 1.6e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME32859.1 - 6.3e-19 68.7 0.3 1.6e-18 67.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Trigger_C PF05698.9 EME32859.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus LRR_4 PF12799.2 EME32860.1 - 8.8e-32 108.1 44.7 6.9e-08 31.9 0.7 5.3 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME32860.1 - 5.8e-23 80.4 32.6 8.3e-09 35.0 1.6 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EME32860.1 - 2.9e-20 69.1 31.4 0.014 15.2 0.1 8.9 9 0 0 9 9 9 8 Leucine Rich Repeat LRR_7 PF13504.1 EME32860.1 - 2.1e-12 45.0 35.5 0.28 11.5 0.7 9.1 9 0 0 9 9 9 7 Leucine rich repeat LRR_6 PF13516.1 EME32860.1 - 0.013 15.4 27.2 2.9 8.2 0.1 8.3 8 1 1 9 9 9 0 Leucine Rich repeat FAM216B PF15107.1 EME32860.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family FH2 PF02181.18 EME32861.1 - 6.6e-69 232.5 0.4 6.6e-69 232.5 0.3 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain ORC3_N PF07034.6 EME32862.1 - 6e-08 32.0 7.6 7.1e-07 28.4 5.3 2.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus TPR_11 PF13414.1 EME32863.1 - 4.9e-39 131.8 33.5 2.7e-08 33.3 0.1 10.3 7 4 3 10 10 10 8 TPR repeat TPR_14 PF13428.1 EME32863.1 - 9.1e-34 112.8 33.1 0.0036 17.8 0.1 15.5 9 4 7 16 16 16 10 Tetratricopeptide repeat TPR_16 PF13432.1 EME32863.1 - 4.2e-33 113.2 27.5 0.00049 20.7 0.0 10.7 7 2 4 12 12 12 8 Tetratricopeptide repeat TPR_19 PF14559.1 EME32863.1 - 2.3e-31 107.9 17.2 0.0081 16.4 0.0 11.4 8 3 5 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 EME32863.1 - 2.6e-30 101.8 44.5 0.00046 19.8 0.0 17.2 17 1 1 18 18 18 8 Tetratricopeptide repeat TPR_17 PF13431.1 EME32863.1 - 2.1e-26 89.8 20.8 0.0053 16.8 0.0 13.0 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EME32863.1 - 1.3e-17 63.4 40.0 0.04 13.8 0.1 12.1 3 2 11 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.23 EME32863.1 - 2.9e-14 51.9 11.8 0.0014 18.1 0.0 12.1 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME32863.1 - 4e-14 51.2 14.4 1.1 9.1 0.0 13.0 15 1 1 16 16 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME32863.1 - 4.5e-08 32.3 13.6 11 6.1 0.0 10.3 11 0 0 11 11 11 0 Tetratricopeptide repeat Suf PF05843.9 EME32863.1 - 5e-08 33.0 8.4 0.012 15.3 0.0 6.5 3 1 3 7 7 7 2 Suppressor of forked protein (Suf) TPR_9 PF13371.1 EME32863.1 - 4.8e-05 23.1 18.1 3.6 7.5 0.1 8.9 7 3 2 10 10 10 1 Tetratricopeptide repeat PPR_3 PF13812.1 EME32863.1 - 0.00019 21.4 8.3 0.78 10.1 0.0 8.4 10 0 0 10 10 8 1 Pentatricopeptide repeat domain Apc3 PF12895.2 EME32863.1 - 0.00059 19.9 24.6 0.54 10.4 0.1 7.1 5 2 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EME32863.1 - 0.00065 19.5 4.9 53 4.1 0.0 8.3 10 0 0 10 10 6 0 PPR repeat Coatomer_E PF04733.9 EME32863.1 - 0.001 18.3 1.7 1.7 7.7 0.0 4.5 5 0 0 5 5 5 1 Coatomer epsilon subunit Mad3_BUB1_I PF08311.7 EME32863.1 - 0.0032 17.2 14.4 36 4.1 0.1 8.1 6 3 1 8 8 8 0 Mad3/BUB1 homology region 1 TPR_10 PF13374.1 EME32863.1 - 0.01 15.7 23.5 5.9 6.9 1.5 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2366 PF10171.4 EME32863.1 - 0.03 13.8 0.2 1 8.8 0.0 2.8 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2366) PPR_1 PF12854.2 EME32863.1 - 2.4 7.6 11.4 15 5.1 0.1 5.9 7 0 0 7 7 7 0 PPR repeat TPR_6 PF13174.1 EME32863.1 - 4 8.1 33.3 25 5.6 0.0 12.5 17 0 0 17 17 14 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EME32864.1 - 4.9e-51 172.8 0.0 7.1e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EME32864.1 - 1.6e-40 137.3 1.6 3.3e-40 136.3 1.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EME32864.1 - 3.3e-21 74.9 0.0 9.6e-21 73.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME32864.1 - 2.3e-08 34.0 2.4 5.3e-08 32.8 1.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME32864.1 - 1.7e-05 24.7 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EME32864.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EME32864.1 - 0.00022 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EME32864.1 - 0.0044 16.2 0.0 0.013 14.7 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FAD-oxidase_C PF02913.14 EME32864.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain MARVEL PF01284.18 EME32865.1 - 0.003 17.3 13.9 0.0052 16.6 5.8 2.4 1 1 1 2 2 2 2 Membrane-associating domain Abi_HHR PF07815.9 EME32865.1 - 0.13 12.4 0.0 0.51 10.4 0.1 1.9 2 0 0 2 2 2 0 Abl-interactor HHR CS PF04969.11 EME32866.1 - 1e-14 54.8 3.3 2.2e-14 53.7 2.3 1.6 1 0 0 1 1 1 1 CS domain Pkinase PF00069.20 EME32867.1 - 3.7e-41 141.0 0.1 2.2e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME32867.1 - 1.8e-11 43.5 0.0 4.2e-06 26.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EME32867.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MRP-S23 PF10484.4 EME32868.1 - 0.0014 18.5 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 COG7 PF10191.4 EME32869.1 - 1.8e-31 108.8 19.4 1.4e-16 59.5 0.7 2.1 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) HTH_19 PF12844.2 EME32869.1 - 0.069 13.2 0.1 0.81 9.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain FANCI_S2 PF14676.1 EME32869.1 - 1.1 9.1 4.9 19 5.1 0.2 4.1 3 1 1 4 4 4 0 FANCI solenoid 2 DUF1664 PF07889.7 EME32869.1 - 1.8 8.4 5.1 1.2 8.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EME32869.1 - 6.1 6.6 7.6 58 3.4 0.0 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKIP_SNW PF02731.10 EME32870.1 - 1.3e-64 216.4 2.8 1.3e-64 216.4 1.9 3.4 3 0 0 3 3 3 1 SKIP/SNW domain FBPase PF00316.15 EME32871.1 - 3.1e-90 302.2 0.0 4.2e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF150 PF02576.12 EME32872.1 - 2.7e-26 91.8 0.0 3.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised BCR, YhbC family COG0779 Sad1_UNC PF07738.8 EME32874.1 - 3.8e-28 97.9 0.0 7.1e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal AAA PF00004.24 EME32875.1 - 9.5e-36 122.9 0.0 2.6e-35 121.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EME32875.1 - 6.2e-07 29.2 0.0 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EME32875.1 - 0.0004 20.5 0.0 0.015 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME32875.1 - 0.001 18.7 0.0 0.0062 16.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EME32875.1 - 0.0011 18.0 0.0 0.0027 16.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Aida_N PF08910.5 EME32875.1 - 0.0041 17.3 0.6 0.011 15.9 0.1 1.9 2 0 0 2 2 2 1 Aida N-terminus AAA_17 PF13207.1 EME32875.1 - 0.013 16.2 0.0 0.06 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME32875.1 - 0.021 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EME32875.1 - 0.037 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME32875.1 - 0.039 13.1 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EME32875.1 - 0.039 13.3 0.0 2.8 7.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain TIP49 PF06068.8 EME32875.1 - 0.045 12.4 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EME32875.1 - 0.052 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EME32875.1 - 0.052 13.5 0.1 0.63 9.9 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EME32875.1 - 0.095 13.0 0.1 2.2 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF3317 PF11779.3 EME32876.1 - 8.3e-08 31.5 4.0 1.1e-07 31.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ribosomal_L17 PF01196.14 EME32877.1 - 5.8e-28 97.2 0.0 7.2e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Got1 PF04178.7 EME32878.1 - 3.3e-28 98.1 15.5 4.5e-28 97.7 10.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Acid_phosphat_B PF03767.9 EME32878.1 - 0.14 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF997 PF06196.7 EME32878.1 - 7.5 6.1 10.2 0.092 12.2 1.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF997) SdpI PF13630.1 EME32878.1 - 9.1 6.0 11.2 0.35 10.6 0.6 2.3 1 1 1 2 2 2 0 SdpI/YhfL protein family TPT PF03151.11 EME32879.1 - 4.6e-11 42.5 9.5 4.6e-11 42.5 6.6 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME32879.1 - 2.2e-10 39.9 25.5 6.3e-10 38.4 17.7 1.6 1 1 0 1 1 1 1 UAA transporter family Miro PF08477.8 EME32879.1 - 1.7e-06 28.5 0.0 5.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein EamA PF00892.15 EME32879.1 - 2.2e-05 24.4 28.1 0.0032 17.4 6.2 3.3 3 1 0 3 3 3 2 EamA-like transporter family Ras PF00071.17 EME32879.1 - 0.0015 17.9 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Ras family DUF258 PF03193.11 EME32879.1 - 0.013 14.6 0.1 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EME32879.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.18 EME32879.1 - 0.041 12.6 0.1 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_29 PF13555.1 EME32879.1 - 0.071 12.6 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 EME32879.1 - 0.074 11.9 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EmrE PF13536.1 EME32879.1 - 0.1 12.8 25.1 0.2 11.8 5.5 3.4 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Arf PF00025.16 EME32879.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.1 EME32879.1 - 0.14 12.1 0.1 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TPT PF03151.11 EME32880.1 - 4.7e-11 42.5 9.5 4.7e-11 42.5 6.6 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME32880.1 - 2.3e-10 39.9 25.5 6.4e-10 38.4 17.7 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME32880.1 - 1.2e-05 25.3 28.8 0.0033 17.4 6.2 3.8 4 1 0 4 4 4 2 EamA-like transporter family Miro PF08477.8 EME32880.1 - 0.047 14.1 0.0 0.19 12.2 0.0 2.0 2 1 0 2 2 2 0 Miro-like protein EmrE PF13536.1 EME32880.1 - 0.1 12.7 25.1 0.2 11.8 5.5 3.4 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Ins134_P3_kin PF05770.6 EME32881.1 - 8.7e-23 80.8 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase DUF1700 PF08006.6 EME32881.1 - 0.18 11.0 4.2 0.3 10.3 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Chitin_synth_2 PF03142.10 EME32881.1 - 1.2 7.4 11.0 1.8 6.8 7.7 1.1 1 0 0 1 1 1 0 Chitin synthase Band_7 PF01145.20 EME32882.1 - 1e-24 87.4 3.5 1.6e-24 86.8 2.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PTS_2-RNA PF01885.11 EME32882.1 - 0.17 11.2 1.1 0.35 10.1 0.7 1.5 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family NHL PF01436.16 EME32883.1 - 1.5e-05 24.7 0.1 0.0079 16.1 0.0 2.8 2 0 0 2 2 2 2 NHL repeat PAS_9 PF13426.1 EME32884.1 - 2.3e-19 69.6 0.0 2.4e-08 34.2 0.1 3.1 2 1 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EME32884.1 - 3.8e-19 68.5 0.0 2.1e-10 40.5 0.0 3.8 2 1 1 3 3 3 2 PAS fold PAS PF00989.19 EME32884.1 - 1.7e-13 50.3 0.5 5.2e-05 23.0 0.0 3.6 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EME32884.1 - 3.7e-12 46.2 0.0 3e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 PAS fold HLH PF00010.21 EME32884.1 - 2.8e-11 42.9 0.6 7.7e-11 41.5 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.1 EME32884.1 - 6e-08 32.6 0.0 0.00021 21.1 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.1 EME32884.1 - 0.0003 20.5 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain Tnp_P_element PF12017.3 EME32884.1 - 0.011 14.9 1.4 0.025 13.8 0.9 1.5 1 0 0 1 1 1 0 Transposase protein HALZ PF02183.13 EME32884.1 - 0.088 12.5 8.8 0.053 13.2 3.8 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pox_vIL-18BP PF05566.7 EME32884.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein Sec3_C_2 PF15278.1 EME32884.1 - 0.2 11.7 4.0 0.24 11.5 0.2 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit DUF342 PF03961.8 EME32884.1 - 0.27 9.5 8.0 0.43 8.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prominin PF05478.6 EME32884.1 - 0.28 8.6 6.0 0.35 8.3 1.6 2.1 2 0 0 2 2 2 0 Prominin Arena_glycoprot PF00798.13 EME32884.1 - 0.31 9.4 4.0 0.5 8.7 2.8 1.3 1 0 0 1 1 1 0 Arenavirus glycoprotein DivIC PF04977.10 EME32884.1 - 5.9 6.4 7.7 0.83 9.1 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EME32884.1 - 6 6.9 13.9 0.55 10.2 0.9 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AAA_25 PF13481.1 EME32885.1 - 8.2e-24 84.0 0.0 1.6e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME32885.1 - 3.6e-17 62.2 0.7 6.6e-15 54.8 0.5 2.2 1 1 0 1 1 1 1 KaiC ChlI PF13541.1 EME32885.1 - 1.3e-09 37.6 0.0 5.4e-09 35.6 0.0 2.1 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.10 EME32885.1 - 2.5e-07 29.8 0.0 5.7e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.24 EME32885.1 - 6e-06 26.4 0.1 1.1e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EME32885.1 - 1.8e-05 24.4 0.0 5.3e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Lon_C PF05362.8 EME32885.1 - 2.7e-05 23.5 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_22 PF13401.1 EME32885.1 - 5.6e-05 23.2 0.1 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME32885.1 - 0.00018 21.5 0.3 0.0011 19.0 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EME32885.1 - 0.00023 20.8 0.1 0.00058 19.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EME32885.1 - 0.00028 21.6 0.0 0.00099 19.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EME32885.1 - 0.00043 20.6 0.1 0.00084 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME32885.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME32885.1 - 0.0015 18.0 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.4 EME32885.1 - 0.0031 16.5 0.1 0.0055 15.7 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EME32885.1 - 0.0042 15.8 0.8 0.01 14.5 0.5 1.8 1 1 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EME32885.1 - 0.0047 17.0 0.0 0.0097 16.0 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EME32885.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GvpD PF07088.6 EME32885.1 - 0.0073 14.6 0.1 1 7.5 0.0 2.1 2 0 0 2 2 2 1 GvpD gas vesicle protein Rad51 PF08423.6 EME32885.1 - 0.015 14.2 0.1 0.35 9.7 0.1 2.2 1 1 0 1 1 1 0 Rad51 NTPase_1 PF03266.10 EME32885.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 1 0 NTPase KTI12 PF08433.5 EME32885.1 - 0.03 13.5 0.4 0.08 12.1 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 EME32885.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME32885.1 - 0.042 12.8 0.0 0.093 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EME32885.1 - 0.058 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EME32885.1 - 0.06 13.0 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EME32885.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 EME32885.1 - 0.11 13.0 0.1 0.34 11.4 0.1 1.9 1 1 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 EME32885.1 - 0.11 11.9 0.2 0.14 11.6 0.1 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EME32885.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 EME32885.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 EME32885.1 - 0.15 11.5 0.1 0.37 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fasciclin PF02469.17 EME32886.1 - 1.2e-21 76.9 1.4 1.8e-21 76.4 1.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Arch_ATPase PF01637.13 EME32887.1 - 0.00052 19.7 0.0 0.0026 17.4 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase